Pi meson radiotherapy for advanced head and neck neoplasms: preliminary results.

PubMed

Khan, K M; Bush, S; Herzon, F; Klingerman, M M

1981-01-01

Under the auspices of the University of New Mexico Cancer Research and Treatment Center, trials are under way at the Los Alamos Meson Physics Facility to evaluate the effects of pi meson irradiation on locally advanced human tumors. This paper summarizes the preliminary results in patients with locally advanced head and neck tumors treated under Phase 1 and Phase II studies. A total of 26 patients were treated between June 1977 and May 1979 with a minimum follow-up of 9 months and a maximum follow-up of 33 months. Sites of disease included the oropharynx in 10 cases (base of tongue in 7, tonsil in 2, and pharyngoepiglottic fold in 1), the supraglottic larynx in 4, the nasopharynx in 5, the oral cavity in 4, the hypopharynx in 2, and the sublingual salivary gland in 1. Twelve of the 26 patients are alive, and 10 survive with no evidence of disease. Doses employed ranged from a minimum of 1,000 peak pion rad in 7 fractions over 9 days to a maximum of 5,4000 peak pion rad in 51 fractions of 89 days. The minimum dose employed for any patients treated with peak pions alone was 3,000 rad. These data are analyzed according to dose, sit, histology, tumor response, local control, and survival. Results from these cases form the basis of the Phase III randomized trials for advanced squamous-cell carcinomas of the head and neck, which are currently in progress.

Method to study complex systems of mesons in lattice QCD

DOE PAGES

Detmold, William; Savage, Martin J.

2010-07-30

Correlation functions involving many hadrons allow finite density systems to be explored with Lattice QCD. Recently, systems with up to 12more » $$\\pi^+$$'s or $K^+$'s have been studied to determine the the $3$-$$\\pi^+$$ and $3$-$K^+$ interactions and the corresponding chemical potential has been determined as a function of density in each case. We derive recursion relations between correlation functions that allow us to extend this work to systems of arbitrary numbers of mesons and to systems containing arbitrary different types of mesons such as $$\\pi^+$$'s, $K^+$'s, $D^0$'s and $B^+$'s. These relations allow for the study of finite-density systems in arbitrary volumes, and the study of high-density systems. Systems comprised of up to N=12 m mesons can be explored with Lattice QCD calculations utilizing $m$ different sources for the quark propagators. As the recursion relations require only a small, N-independent, number of operations to derive the N+1 meson contractions from the N meson contractions, they are compuationally feasible.« less

A PI3-kinase-mediated negative feedback regulates neuronal excitability.

PubMed

Howlett, Eric; Lin, Curtis Chun-Jen; Lavery, William; Stern, Michael

2008-11-01

Use-dependent downregulation of neuronal activity (negative feedback) can act as a homeostatic mechanism to maintain neuronal activity at a particular specified value. Disruption of this negative feedback might lead to neurological pathologies, such as epilepsy, but the precise mechanisms by which this feedback can occur remain incompletely understood. At one glutamatergic synapse, the Drosophila neuromuscular junction, a mutation in the group II metabotropic glutamate receptor gene (DmGluRA) increased motor neuron excitability by disrupting an autocrine, glutamate-mediated negative feedback. We show that DmGluRA mutations increase neuronal excitability by preventing PI3 kinase (PI3K) activation and consequently hyperactivating the transcription factor Foxo. Furthermore, glutamate application increases levels of phospho-Akt, a product of PI3K signaling, within motor nerve terminals in a DmGluRA-dependent manner. Finally, we show that PI3K increases both axon diameter and synapse number via the Tor/S6 kinase pathway, but not Foxo. In humans, PI3K and group II mGluRs are implicated in epilepsy, neurofibromatosis, autism, schizophrenia, and other neurological disorders; however, neither the link between group II mGluRs and PI3K, nor the role of PI3K-dependent regulation of Foxo in the control of neuronal excitability, had been previously reported. Our work suggests that some of the deficits in these neurological disorders might result from disruption of glutamate-mediated homeostasis of neuronal excitability.

Photoproduction of the f 1 ( 1285 ) meson

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dickson, Ryan; Schumacher, Reinhard A.; Adhikari, K. P.

Themore » $$f_1(1285)$$ meson with mass $$1281.0 \\pm 0.8$$ MeV/$c^2$ and width $$18.4 \\pm 1.4$$ MeV (FWHM) was measured for the first time in photoproduction from a proton target using CLAS at Jefferson Lab. Differential cross sections were obtained via the $$\\eta\\pi^{+}\\pi^{-}$$, $$K^+\\bar{K}^0\\pi^-$$, and $$K^-K^0\\pi^+$$ decay channels from threshold up to a center-of-mass energy of 2.8 GeV. mass, width, and an amplitude analysis of the $$\\eta\\pi^{+}\\pi^{-}$$ final-state Dalitz distribution are consistent with the axial-vector $J^P=1^+$ $$f_1(1285)$$ identity, rather than the pseudoscalar $0^-$ $$\\eta(1295)$$. production mechanism is more consistent with $s$-channel decay of a high-mass $N^*$ state, and not with $t$-channel meson exchange. Decays to $$\\eta\\pi\\pi$$ go dominantly via the intermediate $$a_0^\\pm(980)\\pi^\\mp$$ states, with the branching ratio $$\\Gamma(a_0\\pi \\text{ (no} \\bar{K} K\\text{)}) / \\Gamma(\\eta\\pi\\pi \\text{(all)}) = 0.74\\pm0.09$$. branching ratios $$\\Gamma(K \\bar{K} \\pi)/\\Gamma(\\eta\\pi\\pi) = 0.216\\pm0.033$$ and $$\\Gamma(\\gamma\\rho^0)/\\Gamma(\\eta\\pi\\pi) = 0.047\\pm0.018$$ were also obtained. first is in agreement with previous data for the $$f_1(1285)$$, while the latter is lower than the world average.« less

Photoproduction of the f 1 ( 1285 ) meson

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dickson, R.; Schumacher, R. A.; Adhikari, K. P.

The f(1)(1285) meson withmass 1281.0 +/- 0.8MeV/c(2) and width 18.4 +/- 1.4MeV (full width at half maximum) was measured for the first time in photoproduction from a proton target using CLAS at Jefferson Lab. Differential cross sections were obtained via the eta pi(+)pi(-), K+(K) over bar (0) pi(-), and (K-K0)pi(+) decay channels from threshold up to a center-of-mass energy of 2.8 GeV. The mass, width, and an amplitude analysis of the eta pi(+)pi(-) final-state Dalitz distribution are consistent with the axial-vector J(P) = 1(+) f(1)(1285) identity, rather than the pseudoscalar 0(-) eta(1295). The production mechanism is more consistent with s-channelmore » decay of a high-mass N* state and not with t-channel meson exchange. Decays to eta pi pi go dominantly via the intermediate a(0)(+/-) (980)pi(-/+) states, with the branching ratio Gamma [a(0)pi (no (K) over barK)]/Gamma[eta pi pi (all)] = 0.74 +/- 0.09. The branching ratios Gamma (K (K) over bar pi)/Gamma(eta pi pi) = 0.216 +/- 0.033 and Gamma (gamma rho(0))/Gamma(eta pi pi) = 0.047 +/- 0.018 were also obtained. The first is in agreement with previous data for the f(1)(1285), while the latter is lower than the world average.« less

Determination of the D{sup 0}{yields}K{sup -}{pi}{sup +}{pi}{sup 0} and D{sup 0}{yields}K{sup -}{pi}{sup +}{pi}{sup +}{pi}{sup -} coherence factors and average strong-phase differences using quantum-correlated measurements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lowrey, N.; Mehrabyan, S.; Selen, M.

The first measurements of the coherence factors (R{sub K{pi}}{sub {pi}{sup 0}} and R{sub K3{pi}}) and the average strong-phase differences ({delta}{sub D}{sup K{pi}}{sup {pi}{sup 0}} and {delta}{sub D}{sup K3{pi}}) for D{sup 0}{yields}K{sup -}{pi}{sup +}{pi}{sup 0} and D{sup 0}{yields}K{sup -}{pi}{sup +}{pi}{sup +}{pi}{sup -} are presented. These parameters can be used to improve the determination of the unitarity triangle angle {gamma} in B{sup -}{yields}DK{sup -} decays, where D is a D{sup 0} or D{sup 0} meson decaying to the same final state. The measurements are made using quantum-correlated, fully reconstructed D{sup 0}D{sup 0} pairs produced in e{sup +}e{sup -} collisions at the {psi}(3770)more » resonance. The measured values are: R{sub K{pi}}{sub {pi}{sup 0}}=0.84{+-}0.07, {delta}{sub D}{sup K{pi}}{sup {pi}{sup 0}}=(227{sub -17}{sup +14}) deg., R{sub K3{pi}}=0.33{sub -0.23}{sup +0.20}, and {delta}{sub D}{sup K3{pi}}=(114{sub -23}{sup +26}) deg. These results indicate significant coherence in the decay D{sup 0}{yields}K{sup -}{pi}{sup +}{pi}{sup 0}, whereas lower coherence is observed in the decay D{sup 0}{yields}K{sup -}{pi}{sup +}{pi}{sup +}{pi}{sup -}. The analysis also results in a small improvement in the knowledge of other D-meson parameters, in particular, the strong-phase difference for D{sup 0}{yields}K{sup -}{pi}{sup +}, {delta}{sub D}{sup K{pi}}, and the mixing parameter y.« less

Further Results on the Production of Neutral Mesons by Photons

DOE R&D Accomplishments Database

Panofsky, W. K. H.; Steinberger, J.; Steller, J.

1951-10-01

Further measurements have been made on the photoproduction of neutral mesons using the gamma-gamma coincidence technique. New data have been obtained on the gamma-gamma correlation curves in beryllium. The angular distribution of the photo mesons in Be has been determined and found to be strongly peaked forward. The dependence on the atomic number A of production has been found to obey an A{sup 2/3} law. Some data obtained for production in hydrogen show that the pi-zero and pi-plus production cross sections are comparable and that the pi-zero excitation curve starts more slowly from threshold than does the pi-plus photo excitation curve.

Chiral anomalies and effective vector meson Lagrangian beyond the tree level

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dominguez, C.A.

1987-12-01

The decays ..pi../sup O/ ..-->.. ..gamma gamma.., rho ..-->.. ..pi gamma.., ..omega.. ..-->.. ..pi gamma.., ..omega.. ..-->.. 3..pi.. and ..gamma.. ..-->.. 3..pi.. are studied in the framework of the chiral invariant effective Vector Meson Lagrangian beyond the tree level. The standard Lagrangian is enlarged by including an infinite number of radial excitations which are summed according to the dual model. As a result tree level diagrams are modified by a universal form factor at each vertex containing off-mass-shell mesons, but still respecting chiral anomaly low energy theorems. These vertex corrections bring the tree level predictions into better agreement with experiment.more » The presence of the ..omega.. ..-->.. 3..pi.. contact term is confirmed but its strength is considerably smaller than at tree level.« less

Dynamical coupled-channels study of {pi}N{yields}{pi}{pi}N reactions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kamano, H.; Julia-Diaz, B.; Department d'Estructura i Constituents de la Materia and Institut de Ciencies del Cosmos, Universitat de Barcelona E-08028 Barcelona

As a step toward performing a complete coupled-channels analysis of the world data of {pi}N,{gamma}*N{yields}{pi}N,{eta}N,{pi}{pi}N reactions, the {pi}N{yields}{pi}{pi}N reactions are investigated starting with the dynamical coupled-channels model developed in Phys. Rev. C 76, 065201 (2007). The channels included are {pi}N,{eta}N, and {pi}{pi}N which has {pi}{delta},{rho}N, and {sigma}N resonant components. The nonresonant amplitudes are generated from solving a set of coupled-channels equations with the meson-baryon potentials defined by effective Lagrangians. The resonant amplitudes are generated from 16 bare excited nucleon (N*) states that are dressed by the nonresonant interactions as constrained by the unitarity condition. The data of total cross sectionsmore » and {pi}N and {pi}{pi} invariant mass distributions of {pi}{sup +}p{yields}{pi}{sup +}{pi}{sup +}n,{pi}{sup +}{pi}{sup 0}p and {pi}{sup -}p{yields}{pi}{sup +}{pi}{sup -}n,{pi}{sup -}{pi}{sup 0}p,{pi}{sup 0}{pi}{sup 0}n reactions from threshold to the invariant mass W=2 GeV can be described to a very large extent. We show the importance of the coupled-channels effects and the strong interference among the contributions from the {pi}{delta},{sigma}N, and {rho}N channels. The large interference between the resonant and nonresonant amplitudes is also demonstrated. Possible future developments are discussed.« less

$pi$$sup +-$ TRACKS IN A FILAMENT SCINTILLATION CHAMBER

DOE Office of Scientific and Technical Information (OSTI.GOV)

Reynolds, G.T.; Swanson, R.A.; Scarl, D.B.

1960-09-01

The performance of a filament scintillation chamber system designed for studies on stopping mesons was studied by exposing it to the 90-Mev pi/sup plus or minus/ beam of the Nevis cyclotron and taking a total of 16,000 photographs. THe results indicate that (1) except for meson tracks, the chamber appears clean even without the 200-mu sec gating and the iron blockhouse, (2) the magnetic field has no effect on the performance and resolution, (3) three or four tracks can appear in a single picture of the 1-in.-diameter chamber without confusion, and (4) even at the highest beam fluxes, the gatingmore » restricts the tracks to those selected by the counter system. Pictures of the distinguishable stopping of pi/ sup +/ and pi/sup -/ mesons are included. (D.L.C.)« less

Measurement of CP Asymmetries and Branching Fractions in B0 -> pi+ pi-, B0 -> K+ pi-, B0 -> pi0 pi0, B0 -> K0 pi0 and Isospin Analysis of B -> pi pi Decays

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aubert, Bernard; Bona, M.; Karyotakis, Y.

2008-08-01

The authors present preliminary results of improved measurements of the CP-violating asymmetries and branching fractions in the decays B{sup 0} {yields} {pi}{sup +}{pi}{sup -}, B{sup 0} {yields} K{sup +}{pi}{sup -}, B{sup 0} {yields} {pi}{sup 0}{pi}{sup 0}, and B{sup 0} {yields} K{sup 0}{pi}{sup 0}. This update includes all data taken at the {Upsilon}(4S) resonance by the BABAR experiment at the asymmetric PEP-II B-meson factory at SLAC, corresponding to 467 {+-} 5 million B{bar B} pairs. They find S{sub {pi}{pi}} = -0.68 {+-} 0.10 {+-} 0.03, C{sub {pi}{pi}} = -0.25 {+-} 0.08 {+-} 0.02, {Alpha}{sub K{sub {pi}}} = -0.107 {+-} 0.016{sub -0.004},{supmore » +0.006}, C{sub {pi}{sup 0}{pi}{sup 0}} = -0.43 {+-} 0.26 {+-} 0.05, {Beta}(B{sup 0} {yields} {pi}{sup 0}{pi}{sup 0}) = (1.83 {+-} 0.21 {+-} 0.13) x 10{sup -6}, {Beta}(B{sup 0} {yields} K{sup 0}{pi}{sup 0}) = (10.1 {+-} 0.6 {+-} 0.4) x 10{sup -6}, where the first error is statistical and the second is systematic. They observe CP violation with a significance of 6.7{sigma} in B{sup 0} {yields} {pi}{sup -} and 6.1{sigma} in B{sup 0} {yields} K{sup +}{pi}{sup -}. Constraints on the Unitarity Triangle angle {alpha} are determined from the isospin relation between all B {yields} {pi}{pi} rates and asymmetries.« less

Dynamical coupled-channels study of {pi}N {right arrow} {pi pi}N reactions.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kamano, H.; Julia-Diaz, B.; Lee, T.-S. H.

As a step toward performing a complete coupled-channels analysis of the world data of {pi}N,{gamma}*N {yields} {pi}N,{eta}N,{pi}{pi}N reactions, the {pi}N {yields} {pi}{pi}N reactions are investigated starting with the dynamical coupled-channels model developed in Phys. Rev. C 76, 065201 (2007). The channels included are {pi}N,{eta}N, and {pi}{pi}N which has {pi}{Delta},{rho}N, and {sigma}N resonant components. The nonresonant amplitudes are generated from solving a set of coupled-channels equations with the meson-baryon potentials defined by effective Lagrangians. The resonant amplitudes are generated from 16 bare excited nucleon (N*) states that are dressed by the nonresonant interactions as constrained by the unitarity condition. The datamore » of total cross sections and {pi}N and {pi}{pi} invariant mass distributions of {pi} + p {yields} {pi} + {pi} + n, {pi} + {pi}0p and {pi} - p {yields} {pi} + {pi} - n, {pi} - {pi}0p,{pi}0{pi}0n reactions from threshold to the invariant mass W = 2 GeV can be described to a very large extent. We show the importance of the coupled-channels effects and the strong interference among the contributions from the {pi}{Delta},{sigma}N, and {rho}N channels. The large interference between the resonant and nonresonant amplitudes is also demonstrated. Possible future developments are discussed.« less

The Diogene 4 pi detector at Saturne

NASA Technical Reports Server (NTRS)

Alard, J. P.; Arnold, J.; Augerat, J.; Babinet, R.; Bastid, N.; Brochard, F.; Costilhes, J. P.; Crouau, M.; De Marco, N.; Drouet, M.;

What Can We Learn from Hadronic and Radiative Decays of Light Mesons?

NASA Astrophysics Data System (ADS)

Kubis, Bastian

2013-04-01

Chiral perturbation theory offers a powerful tool for the investigation of light pseudoscalar mesons. It incorporates the fundamental symmetries of QCD, interrelates various processes, and allows to link these to the light quark masses. Its shortcomings lie in a limited energy range: the radius of convergence of the chiral expansion is confined to below resonance scales. Furthermore, the strongest consequences of chiral symmetry are manifest for pseudoscalars (pions, kaons, eta) only: vector mesons, e.g., have a severe impact in particular for reactions involving photons. In this talk, I advocate dispersions relations as another model-independent tool to extend the applicability range of chiral perturbation theory. They even allow to tackle the physics of vector mesons in a rigorous way. It will be shown how dispersive methods can be used to resum large rescattering effects, and to provide model-independent links between hadronic and radiative decay modes. Examples to be discussed will include decays of the eta meson, giving access to light-quark-mass ratios or allowing to test the chiral anomaly; and meson transition form factors, which have an important impact on the hadronic light-by-light-scattering contribution to the anomalous magnetic moment of the muon.

Observation of orbitally excited B(s) mesons.

PubMed

Aaltonen, T; Abulencia, A; Adelman, J; Akimoto, T; Albrow, M G; Alvarez González, B; Amerio, S; Amidei, D; Anastassov, A; Annovi, A; Antos, J; Apollinari, G; Apresyan, A; Arisawa, T; Artikov, A; Ashmanskas, W; Attal, A; Aurisano, A; Azfar, F; Azzi-Bacchetta, P; Azzurri, P; Bacchetta, N; Badgett, W; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Baroiant, S; Bartsch, V; Bauer, G; Beauchemin, P-H; Bedeschi, F; Bednar, P; Behari, S; Bellettini, G; Bellinger, J; Belloni, A; Benjamin, D; Beretvas, A; Beringer, J; Berry, T; Bhatti, A; Binkley, M; Bisello, D; Bizjak, I; Blair, R E; Blocker, C; Blumenfeld, B; Bocci, A; Bodek, A; Boisvert, V; Bolla, G; Bolshov, A; Bortoletto, D; Boudreau, J; Boveia, A; Brau, B; Brigliadori, L; Bromberg, C; Brubaker, E; Budagov, J; Budd, H S; Budd, S; Burkett, K; Busetto, G; Bussey, P; Buzatu, A; Byrum, K L; Cabrera, S; Campanelli, M; Campbell, M; Canelli, F; Canepa, A; Carlsmith, D; Carosi, R; Carrillo, S; Carron, S; Casal, B; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavalli-Sforza, M; Cerri, A; Cerrito, L; Chang, S H; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Chlebana, F; Cho, K; Chokheli, D; Chou, J P; Choudalakis, G; Chuang, S H; Chung, K; Chung, W H; Chung, Y S; Ciobanu, C I; Ciocci, M A; Clark, A; Clark, D; Compostella, G; Convery, M E; Conway, J; Cooper, B; Copic, K; Cordelli, M; Cortiana, G; Crescioli, F; Cuenca Almenar, C; Cuevas, J; Culbertson, R; Cully, J C; Dagenhart, D; Datta, M; Davies, T; de Barbaro, P; De Cecco, S; Deisher, A; De Lentdecker, G; De Lorenzo, G; Dell'orso, M; Demortier, L; Deng, J; Deninno, M; De Pedis, D; Derwent, P F; Di Giovanni, G P; Dionisi, C; Di Ruzza, B; Dittmann, J R; D'Onofrio, M; Donati, S; Dong, P; Donini, J; Dorigo, T; Dube, S; Efron, J; Erbacher, R; Errede, D; Errede, S; Eusebi, R; Fang, H C; Farrington, S; Fedorko, W T; Feild, R G; Feindt, M; Fernandez, J P; Ferrazza, C; Field, R; Flanagan, G; Forrest, R; Forrester, S; Franklin, M; Freeman, J C; Furic, I; Gallinaro, M; Galyardt, J; Garberson, F; Garcia, J E; Garfinkel, A F; Gerberich, H; Gerdes, D; Giagu, S; Giannetti, P; Gibson, K; Gimmell, J L; Ginsburg, C M; Giokaris, N; Giordani, M; Giromini, P; Giunta, M; Glagolev, V; Glenzinski, D; Gold, M; Goldschmidt, N; Golossanov, A; Gomez, G; Gomez-Ceballos, G; Goncharov, M; González, O; Gorelov, I; Goshaw, A T; Goulianos, K; Gresele, A; Grinstein, S; Grosso-Pilcher, C; Grundler, U; Guimaraes da Costa, J; Gunay-Unalan, Z; Haber, C; Hahn, K; Hahn, S R; Halkiadakis, E; Hamilton, A; Han, B-Y; Han, J Y; Handler, R; Happacher, F; Hara, K; Hare, D; Hare, M; Harper, S; Harr, R F; Harris, R M; Hartz, M; Hatakeyama, K; Hauser, J; Hays, C; Heck, M; Heijboer, A; Heinemann, B; Heinrich, J; Henderson, C; Herndon, M; Heuser, J; Hewamanage, S; Hidas, D; Hill, C S; Hirschbuehl, D; Hocker, A; Hou, S; Houlden, M; Hsu, S-C; Huffman, B T; Hughes, R E; Husemann, U; Huston, J; Incandela, J; Introzzi, G; Iori, M; Ivanov, A; Iyutin, B; James, E; Jayatilaka, B; Jeans, D; Jeon, E J; Jindariani, S; Johnson, W; Jones, M; Joo, K K; Jun, S Y; Jung, J E; Junk, T R; Kamon, T; Kar, D; Karchin, P E; Kato, Y; Kephart, R; Kerzel, U; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kimura, N; Kirsch, L; Klimenko, S; Klute, M; Knuteson, B; Ko, B R; Koay, S A; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kraus, J; Kreps, M; Kroll, J; Krumnack, N; Kruse, M; Krutelyov, V; Kubo, T; Kuhlmann, S E; Kuhr, T; Kulkarni, N P; Kusakabe, Y; Kwang, S; Laasanen, A T; Lai, S; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; Lecompte, T; Lee, J; Lee, J; Lee, Y J; Lee, S W; Lefèvre, R; Leonardo, N; Leone, S; Levy, S; Lewis, J D; Lin, C; Lin, C S; Lindgren, M; Lipeles, E; Lister, A; Litvintsev, D O; Liu, T; Lockyer, N S; Loginov, A; Loreti, M; Lovas, L; Lu, R-S; Lucchesi, D; Lueck, J; Luci, C; Lujan, P; Lukens, P; Lungu, G; Lyons, L; Lys, J; Lysak, R; Lytken, E; Mack, P; Macqueen, D; Madrak, R; Maeshima, K; Makhoul, K; Maki, T; Maksimovic, P; Malde, S; Malik, S; Manca, G; Manousakis, A; Margaroli, F; Marino, C; Marino, C P; Martin, A; Martin, M; Martin, V; Martínez, M; Martínez-Ballarín, R; Maruyama, T; Mastrandrea, P; Masubuchi, T; Mattson, M E; Mazzanti, P; McFarland, K S; McIntyre, P; McNulty, R; Mehta, A; Mehtala, P; Menzemer, S; Menzione, A; Merkel, P; Mesropian, C; Messina, A; Miao, T; Miladinovic, N; Miles, J; Miller, R; Mills, C; Milnik, M; Mitra, A; Mitselmakher, G; Miyake, H; Moed, S; Moggi, N; Moon, C S; Moore, R; Morello, M; Movilla Fernandez, P; Mülmenstädt, J; Mukherjee, A; Muller, Th; Mumford, R; Murat, P; Mussini, M; Nachtman, J; Nagai, Y; Nagano, A; Naganoma, J; Nakamura, K; Nakano, I; Napier, A; Necula, V; Neu, C; Neubauer, M S; Nielsen, J; Nodulman, L; Norman, M; Norniella, O; Nurse, E; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Oldeman, R; Orava, R; Osterberg, K; Pagan Griso, S; Pagliarone, C; Palencia, E; Papadimitriou, V; Papaikonomou, A; Paramonov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Pellett, D E; Penzo, A; Phillips, T J; Piacentino, G; Piedra, J; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Portell, X; Poukhov, O; Pounder, N; Prakoshyn, F; Pronko, A; Proudfoot, J; Ptohos, F; Punzi, G; Pursley, J; Rademacker, J; Rahaman, A; Ramakrishnan, V; Ranjan, N; Redondo, I; Reisert, B; Rekovic, V; Renton, P; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robson, A; Rodrigo, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Roy, P; Ruiz, A; Russ, J; Rusu, V; Saarikko, H; Safonov, A; Sakumoto, W K; Salamanna, G; Saltó, O; Santi, L; Sarkar, S; Sartori, L; Sato, K; Savard, P; Savoy-Navarro, A; Scheidle, T; Schlabach, P; Schmidt, E E; Schmidt, M A; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scott, A L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sfyrla, A; Shalhout, S Z; Shapiro, M D; Shears, T; Shepard, P F; Sherman, D; Shimojima, M; Shochet, M; Shon, Y; Shreyber, I; Sidoti, A; Sinervo, P; Sisakyan, A; Slaughter, A J; Slaunwhite, J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Soderberg, M; Soha, A; Somalwar, S; Sorin, V; Spalding, J; Spinella, F; Spreitzer, T; Squillacioti, P; Stanitzki, M; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Stuart, D; Suh, J S; Sukhanov, A; Sun, H; Suslov, I; Suzuki, T; Taffard, A; Takashima, R; Takeuchi, Y; Tanaka, R; Tecchio, M; Teng, P K; Terashi, K; Thom, J; Thompson, A S; Thompson, G A; Thomson, E; Tipton, P; Tiwari, V; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Tourneur, S; Trischuk, W; Tu, Y; Turini, N; Ukegawa, F; Uozumi, S; Vallecorsa, S; van Remortel, N; Varganov, A; Vataga, E; Vázquez, F; Velev, G; Vellidis, C; Veszpremi, V; Vidal, M; Vidal, R; Vila, I; Vilar, R; Vine, T; Vogel, M; Volobouev, I; Volpi, G; Würthwein, F; Wagner, P; Wagner, R G; Wagner, R L; Wagner, J; Wagner, W; Wakisaka, T; Wallny, R; Wang, S M; Warburton, A; Waters, D; Weinberger, M; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Wynne, S M; Yagil, A; Yamamoto, K; Yamaoka, J; Yamashita, T; Yang, C; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zaw, I; Zhang, X; Zheng, Y; Zucchelli, S

2008-02-29

We report the observation of two narrow resonances consistent with states of orbitally excited (L=1) B_(s) mesons using 1 fb;(-1) of pp[over ] collisions at sqrt[s]=1.96 TeV collected with the Collider Detector at Fermilab II detector at the Fermilab Tevatron. We use two-body decays into K- and B+ mesons reconstructed as B(+)-->J/psiK(+), J/psi-->mu(+)mu(-) or B(+)-->D[over ](0)pi(+), D[over ](0)-->K(+)pi(-). We deduce the masses of the two states to be m(B_(s1))=5829.4+/-0.7 MeV/c(2) and m(B_(s2);(*))=5839.6+/-0.7 MeV/c;(2).

Measurement of the branching fractions of exclusive _B-->D(*)(pi)l-_nu l decays in events with a fully reconstructed B meson.

PubMed

Aubert, B; Bona, M; Karyotakis, Y; Lees, J P; Poireau, V; Prudent, X; Tisserand, V; Zghiche, A; Garra Tico, J; Grauges, E; Lopez, L; Palano, A; Pappagallo, M; Eigen, G; Stugu, B; Sun, L; Abrams, G S; Battaglia, M; Brown, D N; Button-Shafer, J; Cahn, R N; Jacobsen, R G; Kadyk, J A; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; Lynch, G; Osipenkov, I L; Ronan, M T; Tackmann, K; Tanabe, T; Wenzel, W A; del Amo Sanchez, P; Hawkes, C M; Soni, N; Watson, A T; Koch, H; Schroeder, T; Walker, D; Asgeirsson, D J; Cuhadar-Donszelmann, T; Fulsom, B G; Hearty, C; Mattison, T S; McKenna, J A; Barrett, M; Khan, A; Saleem, M; Teodorescu, L; Blinov, V E; Bukin, A D; Buzykaev, A R; Druzhinin, V P; Golubev, V B; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Todyshev, K Yu; Bondioli, M; Curry, S; Eschrich, I; Kirkby, D; Lankford, A J; Lund, P; Mandelkern, M; Martin, E C; Stoker, D P; Abachi, S; Buchanan, C; Gary, J W; Liu, F; Long, O; Shen, B C; Vitug, G M; Yasin, Z; Zhang, L; Paar, H P; Rahatlou, S; Sharma, V; Campagnari, C; Hong, T M; Kovalskyi, D; Richman, J D; Beck, T W; Eisner, A M; Flacco, C J; Heusch, C A; Kroseberg, J; Lockman, W S; Schalk, T; Schumm, B A; Seiden, A; Wilson, M G; Winstrom, L O; Chen, E; Cheng, C H; Doll, D A; Echenard, B; Fang, F; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Andreassen, R; Mancinelli, G; Meadows, B T; Mishra, K; Sokoloff, M D; Blanc, F; Bloom, P C; Ford, W T; Hirschauer, J F; Kreisel, A; Nagel, M; Nauenberg, U; Olivas, A; Smith, J G; Ulmer, K A; Wagner, S R; Ayad, R; Gabareen, A M; Soffer, A; Toki, W H; Wilson, R J; Altenburg, D D; Feltresi, E; Hauke, A; Jasper, H; Karbach, M; Merkel, J; Petzold, A; Spaan, B; Wacker, K; Klose, V; Kobel, M J; Lacker, H M; Mader, W F; Nogowski, R; Schubert, J; Schubert, K R; Schwierz, R; Sundermann, J E; Volk, A; Bernard, D; Bonneaud, G R; Latour, E; Thiebaux, Ch; Verderi, M; Clark, P J; Gradl, W; Playfer, S; Robertson, A I; Watson, J E; Andreotti, M; Bettoni, D; Bozzi, C; Calabrese, R; Cecchi, A; Cibinetto, G; Franchini, P; Luppi, E; Negrini, M; Petrella, A; Piemontese, L; Prencipe, E; Santoro, V; Anulli, F; Baldini-Ferroli, R; Calcaterra, A; de Sangro, R; Finocchiaro, G; Pacetti, S; Patteri, P; Peruzzi, I M; Piccolo, M; Rama, M; Zallo, A; Buzzo, A; Contri, R; Lo Vetere, M; Macri, M M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Chaisanguanthum, K S; Morii, M; Dubitzky, R S; Marks, J; Schenk, S; Uwer, U; Bard, D J; Dauncey, P D; Nash, J A; Panduro Vazquez, W; Tibbetts, M; Behera, P K; Chai, X; Charles, M J; Mallik, U; Cochran, J; Crawley, H B; Dong, L; Eyges, V; Meyer, W T; Prell, S; Rosenberg, E I; Rubin, A E; Gao, Y Y; Gritsan, A V; Guo, Z J; Lae, C K; Denig, A G; Fritsch, M; Schott, G; Arnaud, N; Béquilleux, J; D'Orazio, A; Davier, M; Firmino da Costa, J; Grosdidier, G; Höcker, A; Lepeltier, V; Le Diberder, F; Lutz, A M; Pruvot, S; Roudeau, P; Schune, M H; Serrano, J; Sordini, V; Stocchi, A; Wang, W F; Wormser, G; Lange, D J; Wright, D M; Bingham, I; Burke, J P; Chavez, C A; Fry, J R; Gabathuler, E; Gamet, R; Hutchcroft, D E; Payne, D J; Touramanis, C; Bevan, A J; George, K A; Di Lodovico, F; Sacco, R; Sigamani, M; Cowan, G; Flaecher, H U; Hopkins, D A; Paramesvaran, S; Salvatore, F; Wren, A C; Brown, D N; Davis, C L; Alwyn, K E; Barlow, N R; Barlow, R J; Chia, Y M; Edgar, C L; Lafferty, G D; West, T J; Yi, J I; Anderson, J; Chen, C; Jawahery, A; Roberts, D A; Simi, G; Tuggle, J M; Dallapiccola, C; Hertzbach, S S; Li, X; Salvati, E; Saremi, S; Cowan, R; Dujmic, D; Fisher, P H; Koeneke, K; Sciolla, G; Spitznagel, M; Taylor, F; Yamamoto, R K; Zhao, M; McLachlin, S E; Patel, P M; Robertson, S H; Lazzaro, A; Lombardo, V; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Côté, D; Simard, M; Taras, P; Viaud, F B; Nicholson, H; De Nardo, G; Lista, L; Monorchio, D; Sciacca, C; Baak, M A; Raven, G; Snoek, H L; Jessop, C P; Knoepfel, K J; LoSecco, J M; Benelli, G; Corwin, L A; Honscheid, K; Kagan, H; Kass, R; Morris, J P; Rahimi, A M; Regensburger, J J; Sekula, S J; Wong, Q K; Blount, N L; Brau, J; Frey, R; Igonkina, O; Kolb, J A; Lu, M; Rahmat, R; Sinev, N B; Strom, D; Strube, J; Torrence, E; Castelli, G; Gagliardi, N; Gaz, A; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Voci, C; Ben-Haim, E; Briand, H; Calderini, G; Chauveau, J; David, P; Del Buono, L; Hamon, O; Leruste, Ph; Malclès, J; Ocariz, J; Perez, A; Prendki, J; Gladney, L; Biasini, M; Covarelli, R; Manoni, E; Angelini, C; Batignani, G; Bettarini, S; Carpinelli, M; Cervelli, A; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Morganti, M; Mazur, M A; Neri, N; Paoloni, E; Rizzo, G; Walsh, J J; Biesiada, J; Lau, Y P; Lopes Pegna, D; Lu, C; Olsen, J; Smith, A J S; Telnov, A V; Baracchini, E; Cavoto, G; del Re, D; Di Marco, E; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Jackson, P D; Mazzoni, M A; Morganti, S; Piredda, G; Polci, F; Renga, F; Voena, C; Ebert, M; Hartmann, T; Schröder, H; Waldi, R; Adye, T; Franek, B; Olaiya, E O; Roethel, W; Wilson, F F; Emery, S; Escalier, M; Gaidot, A; Ganzhur, S F; Hamel de Monchenault, G; Kozanecki, W; Vasseur, G; Yèche, Ch; Zito, M; Chen, X R; Liu, H; Park, W; Purohit, M V; White, R M; Wilson, J R; Allen, M T; Aston, D; Bartoldus, R; Bechtle, P; Benitez, J F; Cenci, R; Coleman, J P; Convery, M R; Dingfelder, J C; Dorfan, J; Dubois-Felsmann, G P; Dunwoodie, W; Field, R C; Glanzman, T; Gowdy, S J; Graham, M T; Grenier, P; Hast, C; Innes, W R; Kaminski, J; Kelsey, M H; Kim, H; Kim, P; Kocian, M L; Leith, D W G S; Li, S; Lindquist, B; Luitz, S; Luth, V; Lynch, H L; MacFarlane, D B; Marsiske, H; Messner, R; Muller, D R; Neal, H; Nelson, S; O'Grady, C P; Ofte, I; Perazzo, A; Perl, M; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Snyder, A; Su, D; Sullivan, M K; Suzuki, K; Swain, S K; Thompson, J M; Va'vra, J; Wagner, A P; Weaver, M; Wisniewski, W J; Wittgen, M; Wright, D H; Wulsin, H W; Yarritu, A K; Yi, K; Young, C C; Ziegler, V; Burchat, P R; Edwards, A J; Majewski, S A; Miyashita, T S; Petersen, B A; Wilden, L; Ahmed, S; Alam, M S; Bula, R; Ernst, J A; Pan, B; Saeed, M A; Zain, S B; Spanier, S M; Wogsland, B J; Eckmann, R; Ritchie, J L; Ruland, A M; Schilling, C J; Schwitters, R F; Izen, J M; Lou, X C; Ye, S; Bianchi, F; Gamba, D; Pelliccioni, M; Bomben, M; Bosisio, L; Cartaro, C; Cossutti, F; Della Ricca, G; Lanceri, L; Vitale, L; Azzolini, V; Lopez-March, N; Martinez-Vidal, F; Milanes, D A; Oyanguren, A; Albert, J; Banerjee, Sw; Bhuyan, B; Hamano, K; Kowalewski, R; Nugent, I M; Roney, J M; Sobie, R J; Gershon, T J; Harrison, P F; Ilic, J; Latham, T E; Mohanty, G B; Band, H R; Chen, X; Dasu, S; Flood, K T; Hollar, J J; Kutter, P E; Pan, Y; Pierini, M; Prepost, R; Vuosalo, C O; Wu, S L

2008-04-18

We report a measurement of the branching fractions for _B-->D(*)(pi)l- _nu(l) decays based on 341.1 fb(-1) of data collected at the Upsilon(4S) resonance with the BABAR detector at the SLAC PEP-II e+ e- storage rings. Events are tagged by fully reconstructing one of the B mesons in a hadronic decay mode. We obtain B(B- -->D(0)l-_nu(l)=(2.33+/-0.09(stat)+/-0.09(syst)%, B(B- -->D(*0)l-_nu(l)=(5.83+/-0.15(stat) +/-0.30(syst) %, B(_B(0)-->D+l-_nu(l)=(2.21+/-0.11(stat) +/-0.12(syst)%, B(_B(0)-->D(*)l-_nu(l)=(5.49+/-0.16(stat)+/-0.25(syst)%, B(B- -->D+pi-l-_nu(l)=(0.42+/-0.06(stat)+/-0.03(syst)%, B(B- -->D(*)+pi-l-_nu(l)=(0.59+/-0.05(stat)+/-0.04(syst)%, B(_B(0)-->D(0)pi+l-_nu(l)=(0.43+/-0.08(stat)+/-0.03(syst)%, and B(_B(0)-->D(*0)pi+l-_nu(l)=(0.48+/-0.08(stat)+/-0.04(syst)%.

Measurement of the eta'-meson mass using J/psi-->gammaeta'.

PubMed

Libby, J; Martin, L; Powell, A; Wilkinson, G; Ecklund, K M; Love, W; Savinov, V; Mendez, H; Ge, J Y; Miller, D H; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Artuso, M; Blusk, S; Khalil, S; Li, J; Mountain, R; Nisar, S; Randrianarivony, K; Sultana, N; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Naik, P; Rademacker, J; Asner, D M; Edwards, K W; Reed, J; Briere, R A; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Alexander, J P; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Galik, R S; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Hunt, J M; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Ledoux, J; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Athar, S B; Patel, R; Yelton, J; Rubin, P; Eisenstein, B I; Karliner, I; Mehrabyan, S; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A

2008-10-31

We measure the mass of the eta;{'} meson using psi(2S)-->pi;{+}pi;{-}J/psi, J/psi-->gammaeta;{'} events acquired with the CLEO-c detector operating at the CESR e;{+}e;{-} collider. Using three decay modes, eta;{'}-->rho;{0}gamma, eta;{'}-->pi;{+}pi;{-}eta with eta-->gammagamma, and eta;{'}-->pi;{+}pi;{-}eta with eta-->pi;{+}pi;{-}pi;{0}, we find M_{eta;{'}}=957.793+/-0.054+/-0.036 MeV, in which the uncertainties are statistical and systematic, respectively. This result is consistent with but substantially more precise than the current world average.

The e{sup +}e{sup -}{yields}2({pi}{sup +}{pi}{sup -}){pi}{sup 0}, 2({pi}{sup +}{pi}{sup -}){eta}, K{sup +}K{sup -}{pi}{sup +}{pi}{sup -}{pi}{sup 0} and K{sup +}K{sup -}{pi}{sup +}{pi}{sup -}{eta} cross sections measured with initial-state radiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aubert, B.; Bona, M.; Boutigny, D.

We study the processes e{sup +}e{sup -}{yields}2({pi}{sup +}{pi}{sup -}){pi}{sup 0}{gamma}, 2({pi}{sup +}{pi}{sup -}){eta}{gamma}, K{sup +}K{sup -}{pi}{sup +}{pi}{sup -}{pi}{sup 0}{gamma} and K{sup +}K{sup -}{pi}{sup +}{pi}{sup -}{eta}{gamma} with the hard photon radiated from the initial state. About 20 000, 4300, 5500, and 375 fully reconstructed events, respectively, are selected from 232 fb{sup -1} of BABAR data. The invariant mass of the hadronic final state defines the effective e{sup +}e{sup -} center-of-mass energy, so that the obtained cross sections from the threshold to about 5 GeV can be compared with corresponding direct e{sup +}e{sup -} measurements, currently available only for the {eta}{pi}{sup +}{pi}{supmore » -} and {omega}{pi}{sup +}{pi}{sup -} submodes of the e{sup +}e{sup -}{yields}2({pi}{sup +}{pi}{sup -}){pi}{sup 0} channel. Studying the structure of these events, we find contributions from a number of intermediate states, and we extract their cross sections where possible. In particular, we isolate the contribution from e{sup +}e{sup -}{yields}{omega}(782){pi}{sup +}{pi}{sup -} and study the {omega}(1420) and {omega}(1650) resonances. In the charmonium region, we observe the J/{psi} in all these final states and several intermediate states, as well as the {psi}(2S) in some modes, and we measure the corresponding branching fractions.« less

The strange meson resonances observed in the reaction K/sup -/p. -->. anti K/sup 0/. pi. /sup +/. pi. /sup -/n at 11 GeV/c

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aston, D.; Awaji, N.; D'Amore, J.

A model incorporating K* resonance contributions and simple backgrounds is shown to quantitatively reproduce the mass dependence of the partial wave amplitudes governing the production and decay of the anti K/sup 0/..pi../sup +/..pi../sup -/ system. A fit of this model to these amplitudes confirms the resonance interpretations of the well-established 1/sup +/ K/sub 1/(1400), the 2/sup +/ K/sub 2/*(1430), the 3/sup -/ K/sub 3/*(1780), and the less well-known 1/sup -/ states, the K*(1410) and the K*(1790). The 4/sup +/ amplitudes are shown to be consistent with the production and decay of the 4/sup +/ K/sub 4/*(2060). A second 2/sup +/more » enhancement at a mass of approx.1.95 GeV/c/sup 2/ can be interpreted as resonant and may be the radial excitation of the K/sub 2/*(1430) or the triplet partner of the K/sub 4/*(2060). New measurements of the masses, widths and branching ratios of these states are given, and the implications of these data for the spectroscopy of the nonstrange meson sector are discussed.« less

Photoproduction and Radiative Decay of η' Meson in CLAS at Jlab

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mbianda Njencheu, Georgie

In this work the η' meson photoproduction cross sections as well as the distribution of the di-pion invariant mass, m(π+π-), in the radiative decay mode n' -> π+π-γ have been measured using the CLAS detector at the Thomas Jefferson National Accelerator Facility using tagged incident photons in the center-of-mass energy range 1.96 GeV - 2.72 GeV. The measurements are performed on a liquid hydrogen target in the reaction γ π -> π η'(η'-> π+π-γ). The analysis is based on the highest statistics collected in this decay channel in comparison to other experiments reported so far. The n' photoproduction cross sectionsmore » measured with radiative decay are in a good agreement with results of previous publication from the same data set in CLAS obtained through η' -> π+π-γ decay mode. Two free parameters, α and Β, are extracted from a model-independent fit to the m(π+π-) distribution and their values are found to agree well with recent theoretical expectations. The results of both parameters confirm the existence of the box anomaly, ρ-ω mixing and effects of the a2(1320) tensor meson in the radiative decay of η'.« less

Dynamical coupled-channel model of meson production reactions in the nucleon resonance region.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Matsuyama, A.; Sato, T.; Lee, T.-S. H.

A dynamical coupled-channel model is presented for investigating the nucleon resonances (N*) in the meson production reactions induced by pions and photons. Our objective is to extract the N* parameters and to investigate the meson production reaction mechanisms for mapping out the quark-gluon substructure of N* from the data. The model is based on an energy-independent Hamiltonian which is derived from a set of Lagrangians by using a unitary transformation method. The constructed model Hamiltonian consists of (a) {Gamma}V for describing the vertex interactions N*{leftrightarrow}MB,{pi}{pi}N with MB={gamma}N,{pi}N,{epsilon}N,{pi}{Delta},{rho}N,{sigma}N, and {rho}{leftrightarrow}{pi}{pi} and {sigma}{leftrightarrow}{pi}{pi}, (b) v22 for the non-resonant MB{yields}M'B' and {pi}{pi}{yields}{pi}{pi} interactions,more » (c) vMB,{pi}{pi}N for the non-resonant MB{yields}{pi}{pi}N transitions, and (d) v{pi}{pi}N,{pi}{pi}N for the non-resonant {pi}{pi}N{yields}{pi}{pi}N interactions. By applying the projection operator techniques, we derive a set of coupled-channel equations which satisfy the unitarity conditions within the channel space spanned by the considered two-particle MB states and the three-particle {pi}{pi}N state. The resulting amplitudes are written as a sum of non-resonant and resonant amplitudes such that the meson cloud effects on the N* decay can be explicitly calculated for interpreting the extracted N* parameters in terms of hadron structure calculations. We present and explain in detail a numerical method based on a spline-function expansion for solving the resulting coupled-channel equations which contain logarithmically divergentone-particle-exchange driving terms {sup (E)}{sub M B, M' B'} resulted from the {pi}{pi}N unitarity cut. This method is convenient, and perhaps more practical and accurate than the commonly employed methods of contour rotation/deformation, for calculating the two-pion production observables. For completeness in explaining our

On spectral temperatures of negative pions produced in d{sup 12}C, {sup 4}He{sup 12}C, and {sup 12}C{sup 12}C collisions at 4.2 A GeV/c

DOE Office of Scientific and Technical Information (OSTI.GOV)

Olimov, Kh. K., E-mail: olimov@comsats.edu.pk; Haseeb, Mahnaz Q., E-mail: mahnazhaseeb@comsats.edu.pk

2013-05-15

The experimental transverse momentum distributions of negative pions produced in d{sup 12}C, {sup 4}He{sup 12}C, and {sup 12}C{sup 12}C collisions at 4.2 A GeV/c were analyzed in the framework of Hagedorn Thermodynamic Model. The spectral temperatures of {pi}{sup -} mesons as well as their relative contributions to the total multiplicity of {pi}{sup -} mesons were extracted from fitting the p{sub t} spectra by two-temperature Hagedorn function. The results were compared systematically with the earlier results obtained from analysis of non-invariant center-of-mass energy spectra of negative pions produced in the analyzed collisions.

Meson-nucleus potentials and the search for meson-nucleus bound states

NASA Astrophysics Data System (ADS)

Metag, V.; Nanova, M.; Paryev, E. Ya.

2017-11-01

Recent experiments studying the meson-nucleus interaction to extract meson-nucleus potentials are reviewed. The real part of the potentials quantifies whether the interaction is attractive or repulsive while the imaginary part describes the meson absorption in nuclei. The review is focused on mesons which are sufficiently long-lived to potentially form meson-nucleus quasi-bound states. The presentation is confined to meson production off nuclei in photon-, pion-, proton-, and light-ion induced reactions and heavy-ion collisions at energies near the production threshold. Tools to extract the potential parameters are presented. In most cases, the real part of the potential is determined by comparing measured meson momentum distributions or excitation functions with collision model or transport model calculations. The imaginary part is extracted from transparency ratio measurements. Results on K+ ,K0 ,K- , η ,η‧ , ω, and ϕ mesons are presented and compared with theoretical predictions. The interaction of K+ and K0 mesons with nuclei is found to be weakly repulsive, while the K- , η ,η‧ , ω and ϕ meson-nucleus potentials are attractive, however, with widely different strengths. Because of meson absorption in the nuclear medium the imaginary parts of the meson-nucleus potentials are all negative, again with a large spread. An outlook on planned experiments in the charm sector is given. In view of the determined potential parameters, the criteria and chances for experimentally observing meson-nucleus quasi-bound states are discussed. The most promising candidates appear to be the η and η‧ mesons.

Exclusive Central $$\\pi^{+}\\pi^{-}$$ Production in Proton Antiproton Collisions at the CDF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zurek, Maria

Exclusivemore » $$\\pi^{=}\\pi^{-}$$ production in proton-antiproton collisions at $$\\sqrt{s}$$ = 0.9 and 1.96 TeV in the Collider Detector at Fermilab has been measured. We select events with two particles with opposite charge in pseudorapidity region -1.3 < $$\\eta$$ < 1.3 with no other particles detected in -5.9 < $$\\eta$$ < 5.9. Particles are assumed to be pions. The $$\\pi^{+}\\pi^{-}$$system is required to have rapidity -1.0 < $y$ < 1.0. The data are expected to be dominated by the double pomeron exchange mechanism. Therefore, the quantum numbers of the central state are constrained. The data extend up to dipion mass M($$\\pi^{+}\\pi^{-}$$) = 5000 MeV/$c^2$. Resonance structures consistent with $$f_0$$ and $$f_2$$(1270) mesons are visible. The results are valuable for light hadron spectroscopy and for providing information about the nature of the pomeron in a region between non-perturbative and perturbative quantum chromodynamics« less

Nucleon Resonance Structure from Exclusive Meson Electroproduction with CLAS and CLAS12

DOE Office of Scientific and Technical Information (OSTI.GOV)

Philip L. Cole, Volker D. Burkert, Ralf W. Gothe, Victor I. Mokeev

2012-12-01

The CLAS detector at Jefferson Lab is a unique instrument, which has provided the lion's share of the world's data on meson photo- and electroproduction in the resonance excitation region. The electroexcitation amplitudes for the low-lying resonances P{sub 33} (1232), P{sub 11} (1440), D{sub 13} (1520), and S {sub 11} (1535) were determined over a wide range of Q{sub 2} < 5.0 GeV{sub 2} in a comprehensive analysis of exclusive single-meson ( {pi}{sup +} n, {pi}{sup 0} p) reactions in the electroproduction off protons. Further, we were able to precisely measure {pi}{sup +}{pi}{sup -}p electroproduction differential cross sections provided bymore » the nearly full kinematic coverage of the CLAS detector. And, for the first time, the electrocouplings of the P{sub 11} (1440), D{sub 13} (1520) excited states are determined from the exclusive-{pi}{sup +}{pi}{sup -}p reaction. Consistent results on the electrocouplings from two-independent analyses (single- and double-pion electroproduction) have provided compelling evidence for the reliable extraction of the N* electrocouplings. And preliminary results on the electrocouplings of the S{sub 31} (1620), S{sub 11} (1650), D{sub 33} (1700), and P{sub 13} (1720) states, which decay preferentially to the N{pi} {pi} final states, have recently become available. Theoretical analyses of these results have revealed that there are two major contributions to the resonance structure: a) an internal quark core and b) an external meson-baryon cloud. These CLAS results have had considerable impact on QCD-based studies on N* structure and in the search for manifestations of the dynamical masses of the dressed quarks. Future CLAS12 N* structure studies at high photon virtualities will considerably extend our capabilities in exploring the nature of confinement in baryons.« less

Measurement of branching fractions and charge asymmetries in B+/--->rho+/-pi0 and B+/--->rho0pi+/- decays, and search for B0-->rho0pi0.

PubMed

Aubert, B; Barate, R; Boutigny, D; Couderc, F; Gaillard, J-M; Hicheur, A; Karyotakis, Y; Lees, J P; Robbe, P; Tisserand, V; Zghiche, A; Palano, A; Pompili, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Day, C T; Gill, M S; Gritsan, A V; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; LeClerc, C; Levi, M E; Lynch, G; Mir, L M; Oddone, P J; Orimoto, T J; Pripstein, M; Roe, N A; Romosan, A; Ronan, M T; Shelkov, V G; Telnov, A V; Wenzel, W A; Ford, K; Harrison, T J; Hawkes, C M; Knowles, D J; Morgan, S E; Penny, R C; Watson, A T; Watson, N K; Goetzen, K; Held, T; Koch, H; Lewandowski, B; Pelizaeus, M; Peters, K; Schmuecker, H; Steinke, M; Boyd, J T; Chevalier, N; Cottingham, W N; Kelly, M P; Latham, T E; Mackay, C; Wilson, F F; Abe, K; Cuhadar-Donszelmann, T; Hearty, C; Mattison, T S; McKenna, J A; Thiessen, D; Kyberd, P; McKemey, A K; Teodorescu, L; Blinov, V E; Bukin, A D; Golubev, V B; Ivanchenko, V N; Kravchenko, E A; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Yushkov, A N; Best, D; Bruinsma, M; Chao, M; Kirkby, D; Lankford, A J; Mandelkern, M; Mommsen, R K; Roethel, W; Stoker, D P; Buchanan, C; Hartfiel, B L; Gary, J W; Layter, J; Shen, B C; Wang, K; del Re, D; Hadavand, H K; Hill, E J; MacFarlane, D B; Paar, H P; Rahatlou, Sh; Sharma, V; Berryhill, J W; Campagnari, C; Dahmes, B; Levy, S L; Long, O; Lu, A; Mazur, M A; Richman, J D; Verkerke, W; Beck, T W; Beringer, J; Eisner, A M; Heusch, C A; Lockman, W S; Schalk, T; Schmitz, R E; Schumm, B A; Seiden, A; Spradlin, P; Turri, M; Walkowiak, W; Williams, D C; Wilson, M G; Albert, J; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Erwin, R J; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Ryd, A; Samuel, A; Yang, S; Jayatilleke, S; Mancinelli, G; Meadows, B T; Sokoloff, M D; Abe, T; Blanc, F; Bloom, P; Chen, S; Clark, P J; Ford, W T; Nauenberg, U; Olivas, A; Rankin, P; Roy, J; Smith, J G; van Hoek, W C; Zhang, L; Harton, J L; Hu, T; Soffer, A; Toki, W H; Wilson, R J; Zhang, J; Altenburg, D; Brandt, T; Brose, J; Colberg, T; Dickopp, M; Dubitzky, R S; Hauke, A; Lacker, H M; Maly, E; Müller-Pfefferkorn, R; Nogowski, R; Otto, S; Schubert, J; Schubert, K R; Schwierz, R; Spaan, B; Wilden, L; Bernard, D; Bonneaud, G R; Brochard, F; Cohen-Tanugi, J; Grenier, P; Thiebaux, Ch; Vasileiadis, G; Verderi, M; Khan, A; Lavin, D; Muheim, F; Playfer, S; Swain, J E; Andreotti, M; Azzolini, V; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Piemontese, L; Sarti, A; Treadwell, E; Baldini-Ferroli, R; Calcaterra, A; de Sangro, R; Falciai, D; Finocchiaro, G; Patteri, P; Piccolo, M; Zallo, A; Buzzo, A; Capra, R; Contri, R; Crosetti, G; Lo Vetere, M; Macri, M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Bailey, S; Morii, M; Won, E; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Eschrich, I; Gaillard, J R; Morton, G W; Nash, J A; Taylor, G P; Grenier, G J; Lee, S-J; Mallik, U; Cochran, J; Crawley, H B; Lamsa, J; Meyer, W T; Prell, S; Rosenberg, E I; Yi, J; Davier, M; Grosdidier, G; Höcker, A; Laplace, S; Le Diberder, F; Lepeltier, V; Lutz, A M; Petersen, T C; Plaszczynski, S; Schune, M H; Tantot, L; Wormser, G; Brigljević, V; Cheng, C H; Lange, D J; Simani, M C; Wright, D M; Bevan, A J; Coleman, J P; Fry, J R; Gabathuler, E; Gamet, R; Kay, M; Parry, R J; Payne, D J; Sloane, R J; Touramanis, C; Back, J J; Harrison, P F; Shorthouse, H W; Vidal, P B; Brown, C L; Cowan, G; Flack, R L; Flaecher, H U; George, S; Green, M G; Kurup, A; Marker, C E; McMahon, T R; Ricciardi, S; Salvatore, F; Vaitsas, G; Winter, M A; Brown, D; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Hart, P A; Hodgkinson, M C; Jackson, F; Lafferty, G D; Lyon, A J; Weatherall, J H; Williams, J C; Farbin, A; Jawahery, A; Kovalskyi, D; Lae, C K; Lillard, V; Roberts, D A; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Koptchev, V B; Moore, T B; Saremi, S; Staengle, H; Willocq, S; Cowan, R; Sciolla, G; Taylor, F; Yamamoto, R K; Mangeol, D J J; Patel, P M; Robertson, S H; Lazzaro, A; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Reidy, J; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Cote-Ahern, D; Taras, P; Nicholson, H; Cartaro, C; Cavallo, N; De Nardo, G; Fabozzi, F; Gatto, C; Lista, L; Paolucci, P; Piccolo, D; Sciacca, C; Baak, M A; Raven, G; LoSecco, J M; Gabriel, T A; Brau, B; Gan, K K; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pulliam, T; Wong, Q K; Brau, J; Frey, R; Igonkina, O; Potter, C T; Sinev, N B; Strom, D; Torrence, E; Colecchia, F; Dorigo, A; Galeazzi, F; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Tiozzo, G; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; de la Vaissière, Ch; Del Buono, L; Hamon, O; John, M J J; Leruste, Ph; Ocariz, J; Pivk, M; Roos, L; Stark, J; T'Jampens, S; Therin, G; Manfredi, P F; Re, V; Behera, P K; Gladney, L; Guo, Q H; Panetta, J; Anulli, F; Biasini, M; Peruzzi, I M; Pioppi, M; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Bucci, F; Calderini, G; Carpinelli, M; Del Gamba, V; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Martinez-Vidal, F; Morganti, M; Neri, N; Paoloni, E; Rama, M; Rizzo, G; Sandrelli, F; Walsh, J; Haire, M; Judd, D; Paick, K; Wagoner, D E; Danielson, N; Elmer, P; Lu, C; Miftakov, V; Olsen, J; Smith, A J S; Tanaka, H A; Varnes, E W; Bellini, F; Cavoto, G; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Mazzoni, M A; Morganti, S; Pierini, M; Piredda, G; Safai Tehrani, F; Voena, C; Christ, S; Wagner, G; Waldi, R; Adye, T; De Groot, N; Franek, B; Geddes, N I; Gopal, G P; Olaiya, E O; Xella, S M; Aleksan, R; Emery, S; Gaidot, A; Ganzhur, S F; Giraud, P-F; Hamel de Monchenault, G; Kozanecki, W; Langer, M; Legendre, M; London, G W; Mayer, B; Schott, G; Vasseur, G; Yeche, Ch; Zito, M; Purohit, M V; Weidemann, A W; Yumiceva, F X; Aston, D; Bartoldus, R; Berger, N; Boyarski, A M; Buchmueller, O L; Convery, M R; Cristinziani, M; Dong, D; Dorfan, J; Dujmic, D; Dunwoodie, W; Elsen, E E; Field, R C; Glanzman, T; Gowdy, S J; Grauges-Pous, E; Hadig, T; Halyo, V; Hast, C; Hryn'ova, T; Innes, W R; Jessop, C P; Kelsey, M H; Kim, P; Kocian, M L; Langenegger, U; Leith, D W G S; Libby, J; Luitz, S; Luth, V; Lynch, H L; Marsiske, H; Messner, R; Muller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Petrak, S; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Simi, G; Snyder, A; Soha, A; Stelzer, J; Su, D; Sullivan, M K; Va'vra, J; Wagner, S R; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wright, D H; Young, C C; Burchat, P R; Edwards, A J; Meyer, T I; Petersen, B A; Roat, C; Ahmed, M; Ahmed, S; Alam, M S; Ernst, J A; Saeed, M A; Saleem, M; Wappler, F R; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Kim, H; Ritchie, J L; Schwitters, R F; Izen, J M; Kitayama, I; Lou, X C; Ye, S; Bianchi, F; Bona, M; Gallo, F; Gamba, D; Borean, C; Bosisio, L; Della Ricca, G; Dittongo, S; Grancagnolo, S; Lanceri, L; Poropat, P; Vitale, L; Vuagnin, G; Panvini, R S; Banerjee, Sw; Brown, C M; Fortin, D; Jackson, P D; Kowalewski, R; Roney, J M; Band, H R; Dasu, S; Datta, M; Eichenbaum, A M; Johnson, J R; Kutter, P E; Li, H; Liu, R; Di Lodovico, F; Mihalyi, A; Mohapatra, A K; Pan, Y; Prepost, R; Sekula, S J; von Wimmersperg-Toeller, J H; Wu, J; Wu, S L; Yu, Z; Neal, H

2004-07-30

We present measurements of branching fractions and charge asymmetries in B-meson decays to rho(+)pi(0), rho(0)pi(+), and rho(0)pi(0). The data sample comprises 89x10(6) Upsilon(4S)-->BBmacr; decays collected with the BABAR detector at the PEP-II asymmetric-energy B Factory at SLAC. We find the charge-averaged branching fractions B(B+-->rho(+)pi(0))=[10.9+/-1.9(stat)+/-1.9(syst)]x10(-6) and B(B+-->rho(0)pi(+))=(9.5+/-1.1+/-0.9)x10(-6), and we set a 90% confidence-level upper limit B(B0-->rho(0)pi(0))<2.9x10(-6). We measure the charge asymmetries ACP(pi(0))(rho(+))=0.24+/-0.16+/-0.06 and ACP(pi(+))(rho(0))=-0.19+/-0.11+/-0.02.

Difference in direct charge-parity violation between charged and neutral B meson decays.

PubMed

Lin, S-W; Unno, Y; Hou, W-S; Chang, P; Adachi, I; Aihara, H; Akai, K; Arinstein, K; Aulchenko, V; Aushev, T; Aziz, T; Bakich, A M; Balagura, V; Barberio, E; Bay, A; Bedny, I; Bitenc, U; Bondar, A; Bozek, A; Bracko, M; Browder, T E; Chang, M-C; Chao, Y; Chen, A; Chen, K-F; Chen, W T; Cheon, B G; Chiang, C-C; Chistov, R; Cho, I-S; Choi, S-K; Choi, Y; Choi, Y K; Cole, S; Dalseno, J; Danilov, M; Dash, M; Drutskoy, A; Eidelman, S; Epifanov, D; Fratina, S; Fujikawa, M; Furukawa, K; Gabyshev, N; Goldenzweig, P; Golob, B; Ha, H; Haba, J; Hara, T; Hayasaka, K; Hayashii, H; Hazumi, M; Heffernan, D; Hokuue, T; Hoshi, Y; Hsiung, Y B; Hyun, H J; Iijima, T; Ikado, K; Inami, K; Ishikawa, A; Ishino, H; Itoh, R; Iwabuchi, M; Iwasaki, M; Iwasaki, Y; Kah, D H; Kaji, H; Kataoka, S U; Kawai, H; Kawasaki, T; Kibayashi, A; Kichimi, H; Kikutani, E; Kim, H J; Kim, S K; Kim, Y J; Kinoshita, K; Korpar, S; Kozakai, Y; Krizan, P; Krokovny, P; Kumar, R; Kuo, C C; Kuzmin, A; Kwon, Y-J; Lee, M J; Lee, S E; Lesiak, T; Li, J; Liu, Y; Liventsev, D; Mandl, F; Marlow, D; McOnie, S; Medvedeva, T; Mimashi, T; Mitaroff, W; Miyabayashi, K; Miyake, H; Miyazaki, Y; Mizuk, R; Mori, T; Nakamura, T T; Nakano, E; Nakao, M; Nakazawa, H; Nishida, S; Nitoh, O; Noguchi, S; Nozaki, T; Ogawa, S; Ogawa, Y; Ohshima, T; Okuno, S; Olsen, S L; Ozaki, H; Pakhlova, G; Park, C W; Park, H; Peak, L S; Pestotnik, R; Peters, M; Piilonen, L E; Poluektov, A; Sahoo, H; Sakai, Y; Schneider, O; Schümann, J; Schwartz, A J; Seidl, R; Senyo, K; Sevior, M E; Shapkin, M; Shen, C P; Shibuya, H; Shidara, T; Shinomiya, S; Shiu, J-G; Shwartz, B; Singh, J B; Sokolov, A; Somov, A; Stanic, S; Staric, M; Sumisawa, K; Sumiyoshi, T; Suzuki, S; Tajima, O; Takasaki, F; Tamura, N; Tanaka, M; Tawada, M; Taylor, G N; Teramoto, Y; Tikhomirov, I; Trabelsi, K; Uehara, S; Ueno, K; Uglov, T; Uno, S; Urquijo, P; Ushiroda, Y; Usov, Y; Varner, G; Varvell, K E; Vervink, K; Villa, S; Wang, C C; Wang, C H; Wang, M-Z; Watanabe, Y; Wedd, R; Wicht, J; Won, E; Yabsley, B D; Yamaguchi, A; Yamashita, Y; Yamauchi, M; Yoshida, M; Yuan, C Z; Yusa, Y; Zhang, C C; Zhang, Z P; Zhilich, V; Zhulanov, V; Zupanc, A

2008-03-20

Equal amounts of matter and antimatter are predicted to have been produced in the Big Bang, but our observable Universe is clearly matter-dominated. One of the prerequisites for understanding this elimination of antimatter is the nonconservation of charge-parity (CP) symmetry. So far, two types of CP violation have been observed in the neutral K meson (K(0)) and B meson (B(0)) systems: CP violation involving the mixing between K(0) and its antiparticle (and likewise for B(0) and ), and direct CP violation in the decay of each meson. The observed effects for both types of CP violation are substantially larger for the B(0) meson system. However, they are still consistent with the standard model of particle physics, which has a unique source of CP violation that is known to be too small to account for the matter-dominated Universe. Here we report that the direct CP violation in charged B(+/-)-->K(+/-)pi(0) decay is different from that in the neutral B(0) counterpart. The direct CP-violating decay rate asymmetry, (that is, the difference between the number of observed B(-)-->K(-)pi(0) event versus B(+)-->K(+) pi(0) events, normalized to the sum of these events) is measured to be about +7%, with an uncertainty that is reduced by a factor of 1.7 from a previous measurement. However, the asymmetry for versus B(0)-->K(+)pi(-) is at the -10% level. Although it is susceptible to strong interaction effects that need further clarification, this large deviation in direct CP violation between charged and neutral B meson decays could be an indication of new sources of CP violation-which would help to explain the dominance of matter in the Universe.

Study of the decay D0 --> K+pi-.

PubMed

Link, J M; Reyes, M; Yager, P M; Anjos, J C; Bediaga, I; Göbel, C; Magnin, J; Massafferi, A; de Miranda, J M; Pepe, I M; dos Reis, A C; Simão, F R; Carrillo, S; Casimiro, E; Sánchez-Hernández, A; Uribe, C; Vazquez, F; Cinquini, L; Cumalat, J P; O'Reilly, B; Ramirez, J E; Vaandering, E W; Butler, J N; Cheung, H W; Gaines, I; Garbincius, P H; Garren, L A; Gottschalk, E; Kasper, P H; Kreymer, A E; Kutschke, R; Bianco, S; Fabbri, F L; Sarwar, S; Zallo, A; Cawlfield, C; Kim, D Y; Rahimi, A; Wiss, J; Gardner, R; Chung, Y S; Kang, J S; Ko, B R; Kwak, J W; Lee, K B; Park, H; Alimonti, G; Boschini, M; Caccianiga, B; D'Angelo, P; DiCorato, M; Dini, P; Giammarchi, M; Inzani, P; Leveraro, F; Malvezzi, S; Menasce, D; Mezzadri, M; Milazzo, L; Moroni, L; Pedrini, D; Pontoglio, C; Prelz, F; Rovere, M; Sala, A; Sala, S; Davenport, T F; Agostino, L; Arena, V; Boca, G; Bonomi, G; Gianini, G; Liguori, G; Merlo, M; Pantea, D; Ratti, S P; Riccardi, C; Segoni, I; Viola, L; Vitulo, P; Hernandez, H; Lopez, A M; Mendez, H; Mendez, L; Mirles, A; Montiel, E; Olaya, D; Paris, A; Quinones, J; Rivera, C; Xiong, W; Zhang, Y; Wilson, J R; Cho, K; Handler, T; Engh, D; Hosack, M; Johns, W E; Nehring, M S; Sheldon, P D; Stenson, K; Webster, M S; Sheaff, M

2001-04-02

Using a large sample of photoproduced charm mesons from the FOCUS experiment at Fermilab (FNAL-E831), we observe the decay D0-->K+pi- with a signal yield of 149+/-31 events compared to a similarly cut sample consisting of 36 760+/-195 D0-->K-pi+ events. We use the observed ratio of D0-->K+pi- to D0-->K-pi+ (0.404+/-0.085+/-0.025)% to obtain a relationship between the D0 mixing and doubly Cabibbo suppressed decay parameters.

Rare radiative decays of the B c meson

NASA Astrophysics Data System (ADS)

Ju, Wan-Li; Wang, Tianhong; Jiang, Yue; Yuan, Han; Wang, Guo-Li

2016-08-01

In this paper, we study the rare radiative processes {B}c\\to {D}{sJ}(*)γ within the Standard Model, where {D}{sJ}(*) stands for the meson {D}s*, {D}s1(2460,2536) or {D}s2*(2573). During the investigations, we consider the contributions from the penguin, annihilation, color-suppressed and color-favored cascade diagrams. Our results show that: (1) the penguin and annihilation contributions are dominant in the branching fractions; (2) for the processes {B}c\\to {D}s*γ and {B}c\\to {D}s1(2460,2536)γ , the effects from the color-suppressed and color-favored cascade diagrams are un-negligible.

Study of the K{sup +}{pi}{sup +}{pi}{sup -} final state in B{sup +}{yields}J/{psi}K{sup +}{pi}{sup +}{pi}{sup -} and B{sup +}{yields}{psi}'K{sup +}{pi}{sup +}{pi}{sup -}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Guler, H.; McGill University, Montreal; Universite de Montreal, Montreal

Using 535x10{sup 6} B-meson pairs collected by the Belle detector at the KEKB e{sup +}e{sup -} collider, we measure branching fractions of (7.16{+-}0.10(stat){+-}0.60(syst)x10{sup -4} for B{sup +}{yields}J/{psi}K{sup +}{pi}{sup +}{pi}{sup -} and (4.31{+-}0.20(stat){+-}0.50(syst))x10{sup -4} for B{sup +}{yields}{psi}'K{sup +}{pi}{sup +}{pi}{sup -}. We perform amplitude analyses to determine the resonant structure of the K{sup +}{pi}{sup +}{pi}{sup -} final state in B{sup +}{yields}J/{psi}K{sup +}{pi}{sup +}{pi}{sup -} and B{sup +}{yields}{psi}'K{sup +}{pi}{sup +}{pi}{sup -} and find that the K{sub 1}(1270) is a prominent component of both decay modes. There is significant interference among the different intermediate states, which leads, in particular, to a striking distortion ofmore » the {rho} line shape due to the {omega}. Based on the results of the fit to the B{sup +}{yields}J/{psi}K{sup +}{pi}{sup +}{pi}{sup -} data, the relative decay fractions of the K{sub 1}(1270) to K{rho}, K{omega}, and K*(892){pi} are consistent with previous measurements, but the decay fraction to K{sub 0}*(1430) is significantly smaller. Finally, by floating the mass and width of the K{sub 1}(1270) in an additional fit of the B{sup +}{yields}J/{psi}K{sup +}{pi}{sup +}{pi}{sup -} data, we measure a mass of (1248.1{+-}3.3(stat){+-}1.4(syst)) MeV/c{sup 2} and a width of (119.5{+-}5.2(stat){+-}6.7(syst)) MeV/c{sup 2} for the K{sub 1}(1270).« less

Analysis of genes involved in the PI3K/Akt pathway in radiation- and MNU-induced rat mammary carcinomas.

PubMed

Showler, Kaye; Nishimura, Mayumi; Daino, Kazuhiro; Imaoka, Tatsuhiko; Nishimura, Yukiko; Morioka, Takamitsu; Blyth, Benjamin J; Kokubo, Toshiaki; Takabatake, Masaru; Fukuda, Maki; Moriyama, Hitomi; Kakinuma, Shizuko; Fukushi, Masahiro; Shimada, Yoshiya

2017-03-01

The PI3K/AKT pathway is one of the most important signaling networks in human breast cancer, and since it was potentially implicated in our preliminary investigations of radiation-induced rat mammary carcinomas, our aim here was to verify its role. We included mammary carcinomas induced by the chemical carcinogen 1-methyl-1-nitrosourea to determine whether any changes were radiation-specific. Most carcinomas from both groups showed activation of the PI3K/AKT pathway, but phosphorylation of AKT1 was often heterogeneous and only present in a minority of carcinoma cells. The negative pathway regulator Inpp4b was significantly downregulated in both groups, compared with in normal mammary tissue, and radiation-induced carcinomas also showed a significant decrease in Pten expression, while the chemically induced carcinomas showed a decrease in Pik3r1 and Pdk1. Significant upregulation of the positive regulators Erbb2 and Pik3ca was observed only in chemically induced carcinomas. However, no genes showed clear correlations with AKT phosphorylation levels, except in individual carcinomas. Only rare carcinomas showed mutations in PI3K/AKT pathway genes, yet these carcinomas did not exhibit stronger AKT phosphorylation. Thus, while AKT phosphorylation is a common feature of rat mammary carcinomas induced by radiation or a canonical chemical carcinogen, the mutation of key genes in the pathways or permanent changes to gene expression of particular signaling proteins do not explain the pathway activation in the advanced cancers. Although AKT signaling likely facilitates cancer development and growth in rat mammary carcinomas, it is unlikely that permanent disruption of the PI3K/AKT pathway genes is a major causal event in radiation carcinogenesis. © The Author 2016. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.

Measurement of inclusive radiative B-meson decay B decaying to X(S) meson-gamma

NASA Astrophysics Data System (ADS)

Ozcan, Veysi Erkcan

Radiative decays of the B meson, B→ Xsgamma, proceed via virtual flavor changing neutral current processes that are sensitive to contributions from high mass scales, either within the Standard Model of electroweak interactions or beyond. In the Standard Model, these transitions are sensitive to the weak interactions of the top quark, and relatively robust predictions of the inclusive decay rate exist. Significant deviation from these predictions could be interpreted as indications for processes not included in the minimal Standard Model, like interactions of charged Higgs or SUSY particles. The analysis of the inclusive photon spectrum from B→ Xsgamma decays is rather challenging due to high backgrounds from photons emitted in the decay of mesons in B decays as well as e+e- annihilation to low mass quark and lepton pairs. Based on 88.5 million BB events collected by the BABAR detector, the photon spectrum above 1.9 GeV is presented. By comparison of the first and second moments of the photon spectrum with QCD predictions (calculated in the kinetic scheme), QCD parameters describing the bound state of the b quark in the B meson are extracted: mb=4.45+/-0.16 GeV/c2m2 p=0.65+/-0.29 GeV2 These parameters are useful input to non-perturbative QCD corrections to the semileptonic B decay rate and the determination of the CKM parameter Vub. Based on these parameters and heavy quark expansion, the full branching fraction is obtained as: BRB→X sgEg >1.6GeV=4.050.32 stat+/-0.38syst +/-0.29model x10-4. This result is in good agreement with previous measurements, the statistical and systematic errors are comparable. It is also in good agreement with the theoretical Standard Model predictions, and thus within the present errors there is no indication of any interactions not accounted for in the Standard Model. This finding implies strong constraints on physics beyond the Standard Model.

Search for Penguin Decays of $B$ Mesons at CDF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kordas, Kostas

2000-01-01

Using a data sample of integrated luminositymore » $$\\int$$ Ldt = 28.9 $$\\pm$$ 1.2 $$pb^{-1}$$ of proton antiproton collisions at a center-of-mass energy $$\\sqrt{s}$$ = 1.8 TeV collected with the CDF detector at the Fermilab Tevatron collider, we searched for "penguin" radiative decays of $$B^0_d$$ and $$B^0_s$$ mesons which involve the flavor-changing neutral-current transition of a $b$ quark into an $s$ quark with the emission of a photon, $$b \\to s\\gamma$$ . Speciffcally, we searched for the decays $$B^0_d \\to K^{*0}$$, $$K^{*0} \\to K^+ \\pi^-$$ and $$B^0_s \\to \\phi\\gamma, \\phi \\to K^+ K^-$$, as well as for the charge conjugate chains....« less

Study of collective flows of protons and $$ \\pi^{{-}}_{}$$ π - -mesons in p+C, Ta and He+Li, C collisions at momenta of 4.2, 4.5 and 10 AGeV/c

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chkhaidze, L.; Chlachidze, G.; Djobava, T.

Collective flows of protons andmore » $$\\pi^{-}$$ -mesons are studied at the momenta of 4.2, 4.5 and 10AGeV/c for p+C, Ta and He+Li, C interactions. The data were obtained from the streamer chamber (SKM-200-GIBS) and from the Propane Bubble Chamber (PBC-500) systems utilized at JINR. A method of Danielewicz and Odyniec has been employed in determining a directed transverse flow of particles. The values of the transverse flow parameter and the strength of the anisotropic emission were defined for each interacting nuclear pair. It is found that the directed flows of protons and pions decrease with increasing the energy and the mass numbers of colliding nucleus pairs. The $$ \\pi^{{-}}_{}$$ -meson and proton flows exhibit opposite directions in all studied interactions, and the flows of protons are directed in the reaction plane. Lastly, the Ultra-relativistic Quantum Molecular Dynamical Model (UrQMD) coupled with the Statistical Multi-fragmentation Model (SMM), satisfactorily describes the obtained experimental results.« less

Study of collective flows of protons and $$ \\pi^{{-}}_{}$$ π - -mesons in p+C, Ta and He+Li, C collisions at momenta of 4.2, 4.5 and 10 AGeV/c

DOE PAGES

Chkhaidze, L.; Chlachidze, G.; Djobava, T.; ...

2016-11-01

Collective flows of protons andmore » $$\\pi^{-}$$ -mesons are studied at the momenta of 4.2, 4.5 and 10AGeV/c for p+C, Ta and He+Li, C interactions. The data were obtained from the streamer chamber (SKM-200-GIBS) and from the Propane Bubble Chamber (PBC-500) systems utilized at JINR. A method of Danielewicz and Odyniec has been employed in determining a directed transverse flow of particles. The values of the transverse flow parameter and the strength of the anisotropic emission were defined for each interacting nuclear pair. It is found that the directed flows of protons and pions decrease with increasing the energy and the mass numbers of colliding nucleus pairs. The $$ \\pi^{{-}}_{}$$ -meson and proton flows exhibit opposite directions in all studied interactions, and the flows of protons are directed in the reaction plane. Lastly, the Ultra-relativistic Quantum Molecular Dynamical Model (UrQMD) coupled with the Statistical Multi-fragmentation Model (SMM), satisfactorily describes the obtained experimental results.« less

New measurements of Cabibbo-suppressed decays of mesons with the CLEO-c detector.

PubMed

Rubin, P; Cawlfield, C; Eisenstein, B I; Karliner, I; Kim, D; Lowrey, N; Naik, P; Sedlack, C; Selen, M; White, E J; Wiss, J; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Gong, D T; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Smith, A; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A; Zweber, P; Ernst, J; Severini, H; Dytman, S A; Love, W; Mehrabyan, S; Savinov, V; Aquines, O; Li, Z; Lopez, A; Mendez, H; Ramirez, J; Xin, B; Huang, G S; Miller, D H; Pavlunin, V; Sanghi, B; Shipsey, I P J; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Coan, T E; Gao, Y S; Liu, F; Stroynowski, R; Artuso, M; Blusk, S; Butt, J; Li, J; Menaa, N; Mountain, R; Nisar, S; Randrianarivony, K; Redjimi, R; Sia, R; Skwarnicki, T; Stone, S; Wang, J C; Zhang, K; Csorna, S E; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Asner, D M; Edwards, K W; Briere, R A; Brock, I; Chen, J; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Adam, N E; Alexander, J P; Berkelman, K; Cassel, D G; Duboscq, J E; Ecklund, K M; Ehrlich, R; Fields, L; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Meyer, T O; Onyisi, P U E; Patterson, J R; Peterson, D; Phillips, E A; Pivarski, J; Riley, D; Ryd, A; Sadoff, A J; Schwarthoff, H; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Weinberger, M; Athar, S B; Avery, P; Breva-Newell, L; Patel, R; Potlia, V; Stoeck, H; Yelton, J

2006-03-03

Using of data collected with the CLEO-c detector, we report on first observations and measurements of Cabibbo-suppressed decays of D mesons in the following six decay modes: pi+ pi- pi0 pi0, pi+ pi+ pi- pi- pi0, pi+ pi0 pi0, pi+ pi+ pi- pi0, eta pi0, and omega pi+ pi-. Improved branching fraction measurements in eight other multipion decay modes are also presented. The measured D --> pi pi rates allow us to extract the ratio of isospin amplitudes A(DeltaI = (3/2) / A(DeltaI = (1/2)) = 0.420 +/- 0.014(stat) +/- 0.016(syst) and the strong phase shift of delta1 = (86.4 +/- 2.8 +/- 3.3) degrees, which is quite large and now more precisely determined.

Nonperturbative quark, gluon, and meson correlators of unquenched QCD

NASA Astrophysics Data System (ADS)

Cyrol, Anton K.; Mitter, Mario; Pawlowski, Jan M.; Strodthoff, Nils

2018-03-01

We present nonperturbative first-principle results for quark, gluon, and meson 1PI correlation functions of two-flavor Landau-gauge QCD in the vacuum. These correlation functions carry the full information about the theory. They are obtained by solving their functional renormalization group equations in a systematic vertex expansion, aiming at apparent convergence. This work represents a crucial prerequisite for quantitative first-principle studies of the QCD phase diagram and the hadron spectrum within this framework. In particular, we have computed the gluon, ghost, quark, and scalar-pseudoscalar meson propagators, as well as gluon, ghost-gluon, quark-gluon, quark, quark-meson, and meson interactions. Our results stress the crucial importance of the quantitatively correct running of different vertices in the semiperturbative regime for describing the phenomena and scales of confinement and spontaneous chiral symmetry breaking without phenomenological input.

Cross Sections for the Reactions e+e to K+ K- pi+pi-, K+ K- pi0pi0, and K+ K- K+ K- Measured Using Initial-State Radiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lees, J.P.; Poireau, V.; Prencipe, E.

2011-08-19

We study the processes e{sup +}e{sup -} {yields} K{sup +}K{sup -}{pi}{sup +}{pi}-{gamma}, K{sup +}K{sup -}{pi}{sup 0}{pi}{sup 0}{gamma}, and K{sup +}K{sup -}K{sup +}K{sup -}{gamma}, where the photon is radiated from the initial state. About 84000, 8000, and 4200 fully reconstructed events, respectively, are selected from 454 fb{sup -1} of BABAR data. The invariant mass of the hadronic final state defines the e{sup +}e{sup -} center-of-mass energy, so that the K{sup +}K{sup -}{pi}{sup +}{pi}{sup -}{gamma} data can be compared with direct measurements of the e{sup +}e{sup -} {yields} K{sup +}K{sup -}{pi}{sup +}{pi}{sup -} reaction. No direct measurements exist for the e{sup +}e{supmore » -} {yields} K{sup +}K{sup -}{pi}{sup 0}{pi}{sup 0} or e{sup +}e{sup -} {yields} K{sup +}K{sup -}K{sup +}K{sup -} reactions, and we present an update of our previous result with doubled statistics. Studying the structure of these events, we find contributions from a number of intermediate states, and extract their cross sections. In particular, we perform a more detailed study of the e{sup +}e{sup -} {yields} {phi}(1020){pi}{pi}{gamma} reaction, and confirm the presence of the Y (2175) resonance in the {phi}(1020)f{sub 0}(980) and K{sup +}K{sup -} f{sub 0}(980) modes. In the charmonium region, we observe the J/{psi} in all three final states and in several intermediate states, as well as the {phi}(2S) in some modes, and measure the corresponding branching fractions.« less

A measurement of B0 meson properties using partially reconstructed B0 to D*- pi+ and B0 tp D*- lepton+ nu-lepton decays with the BABAR detector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barrera, Barbara

The two B{sup 0} decay processes B{sup 0} {yields} D*{sup -} {pi}{sup +} and B{sup 0} {yields} D*{sup -} {ell}{sup +} {nu}{sub {ell}} have been studied by means of a partial reconstruction technique using a data sample collected with the BABAR detector at the PEP-II storage ring. To increase statistics, only the soft {pi}{sup -} from the decay D*{sup -} {yields} {pi}{sup -} D{sup 0} was used in association with either an oppositely-charged high-momentum pion or lepton. Events were then identified by exploiting the constraints from the simple kinematics of {Upsilon}(4S) decays. A clear signature is obtained in each case.more » The position of the B{sup 0} decay point was obtained from the reconstructed {pi}{sup +} ({ell}{sup +}){pi}{sup -} vertex. The position of the other {bar B}{sup 0} in the event was also determined. Taking advantage of the boost given to the {Upsilon}(4S) system by the asymmetric beam energies of PEP-II, the lifetime of the B{sup 0} meson has been measured from the separation distance between the two vertices along the beam direction.« less

Radiative lifetimes of the CN (A 2 Pi i) electronic state

NASA Technical Reports Server (NTRS)

Lu, Richang; Huang, Yuhui; Halpern, Joshua B.

1992-01-01

Radiative lifetimes have been measured for CN (A 2 Pi i v-prime = 2...7). Ground-state radicals formed in the 193 nm photolysis of C2N2 and ClCN were excited to A 2 Pi i v-prime = 2...7 vibrational levels. The decay was monitored by following the fluorescence. Cascading effects were eliminated by working at low pressures and monitoring emission from a single vibrational band. Quenching rates and zero-pressure radiative lifetimes were obtained from Stern-Volmer plots. The lifetimes are significantly lower than previous measurements and theoretical calculations for vibrational states v-prime over 2.

Role of the N*(1535) in pp{yields}pp{phi} and {pi}{sup -}p{yields}n{phi} reactions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xie Jujun; Graduate University of Chinese Academy of Sciences, Beijing 100049; Zou Bingsong

2008-01-15

The near-threshold {phi}-meson production in proton-proton and {pi}{sup -}p collisions is studied with the assumption that the production mechanism is due to the sub-N{phi}-threshold N*(1535) resonance. The {pi}{sup 0}-,{eta}-, and {rho}{sup 0}-meson exchanges for proton-proton collisions are considered. It is shown that the contribution to the pp{yields}pp{phi} reaction from the t-channel {pi}{sup 0}-meson exchange is dominant. With a significant N*(1535)N{phi} coupling [g{sub N*(1535)N{phi}}{sup 2}/4{pi}=0.13], both pp{yields}pp{phi} and {pi}{sup -}p{yields}n{phi} data are very well reproduced. The significant coupling of the N*(1535) resonance to N{phi} is compatible with previous indications of a large ss component in the quark wave function of themore » N*(1535) resonance and may be the real origin of the significant enhancement of the {phi} production over the naive OZI-rule predictions.« less

Analysis of genes involved in the PI3K/Akt pathway in radiation- and MNU-induced rat mammary carcinomas

PubMed Central

Showler, Kaye; Nishimura, Mayumi; Imaoka, Tatsuhiko; Nishimura, Yukiko; Morioka, Takamitsu; Blyth, Benjamin J.; Kokubo, Toshiaki; Takabatake, Masaru; Fukuda, Maki; Moriyama, Hitomi; Kakinuma, Shizuko; Fukushi, Masahiro

2017-01-01

Abstract The PI3K/AKT pathway is one of the most important signaling networks in human breast cancer, and since it was potentially implicated in our preliminary investigations of radiation-induced rat mammary carcinomas, our aim here was to verify its role. We included mammary carcinomas induced by the chemical carcinogen 1-methyl-1-nitrosourea to determine whether any changes were radiation-specific. Most carcinomas from both groups showed activation of the PI3K/AKT pathway, but phosphorylation of AKT1 was often heterogeneous and only present in a minority of carcinoma cells. The negative pathway regulator Inpp4b was significantly downregulated in both groups, compared with in normal mammary tissue, and radiation-induced carcinomas also showed a significant decrease in Pten expression, while the chemically induced carcinomas showed a decrease in Pik3r1 and Pdk1. Significant upregulation of the positive regulators Erbb2 and Pik3ca was observed only in chemically induced carcinomas. However, no genes showed clear correlations with AKT phosphorylation levels, except in individual carcinomas. Only rare carcinomas showed mutations in PI3K/AKT pathway genes, yet these carcinomas did not exhibit stronger AKT phosphorylation. Thus, while AKT phosphorylation is a common feature of rat mammary carcinomas induced by radiation or a canonical chemical carcinogen, the mutation of key genes in the pathways or permanent changes to gene expression of particular signaling proteins do not explain the pathway activation in the advanced cancers. Although AKT signaling likely facilitates cancer development and growth in rat mammary carcinomas, it is unlikely that permanent disruption of the PI3K/AKT pathway genes is a major causal event in radiation carcinogenesis. PMID:27738081

Decay constants and radiative decays of heavy mesons in light-front quark model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Choi, Ho-Meoyng

2007-04-01

We investigate the magnetic dipole decays V{yields}P{gamma} of various heavy-flavored mesons such as (D,D*,D{sub s},D{sub s}*,{eta}{sub c},J/{psi}) and (B,B*,B{sub s},B{sub s}*,{eta}{sub b},{upsilon}) using the light-front quark model constrained by the variational principle for the QCD-motivated effective Hamiltonian. The momentum dependent form factors F{sub VP}(q{sup 2}) for V{yields}P{gamma}* decays are obtained in the q{sup +}=0 frame and then analytically continued to the timelike region by changing q{sub perpendicular} to iq{sub perpendicular} in the form factors. The coupling constant g{sub VP{gamma}} for real photon case is then obtained in the limit as q{sup 2}{yields}0, i.e. g{sub VP{gamma}}=F{sub VP}(q{sup 2}=0). The weak decaymore » constants of heavy pseudoscalar and vector mesons are also calculated. Our numerical results for the decay constants and radiative decay widths for the heavy-flavored mesons are overall in good agreement with the available experimental data as well as other theoretical model calculations.« less

Charmless hadronic B decays into a tensor meson

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cheng, Hai-Yang; C. N. Yang Institute for Theoretical Physics, State University of New York Stony Brook, Stony Brook, New York 11794; Yang, Kwei-Chou

2011-02-01

Two-body charmless hadronic B decays involving a tensor meson in the final state are studied within the framework of QCD factorization (QCDF). Because of the G-parity of the tensor meson, both the chiral-even and chiral-odd two-parton light-cone distribution amplitudes of the tensor meson are antisymmetric under the interchange of momentum fractions of the quark and antiquark in the SU(3) limit. Our main results are: (i) In the naieve factorization approach, the decays such as B{sup -}{yields}K{sub 2}*{sup 0}{pi}{sup -} and B{sup 0}{yields}K{sub 2}*{sup -}{pi}{sup +} with a tensor meson emitted are prohibited because a tensor meson cannot be created frommore » the local V-A or tensor current. Nevertheless, the decays receive nonfactorizable contributions in QCDF from vertex, penguin and hard spectator corrections. The experimental observation of B{sup -}{yields}K{sub 2}*{sup 0}{pi}{sup -} indicates the importance of nonfactorizable effects. (ii) For penguin-dominated B{yields}TP and TV decays, the predicted rates in naieve factorization are usually too small by 1 to 2 orders of magnitude. In QCDF, they are enhanced by power corrections from penguin annihilation and nonfactorizable contributions. (iii) The dominant penguin contributions to B{yields}K{sub 2}*{eta}{sup (')} arise from the processes: (a) b{yields}sss{yields}s{eta}{sub s} and (b) b{yields}sqq{yields}qK{sub 2}* with {eta}{sub q}=(uu+dd)/{radical}(2) and {eta}{sub s}=ss. The interference, constructive for K{sub 2}*{eta}{sup '} and destructive for K{sub 2}*{eta}, explains why {Gamma}(B{yields}K{sub 2}*{eta}{sup '})>>{Gamma}(B{yields}K{sub 2}*{eta}). (iv) We use the measured rates of B{yields}K{sub 2}*({omega},{phi}) to extract the penguin-annihilation parameters {rho}{sub A}{sup TV} and {rho}{sub A}{sup VT} and the observed longitudinal polarization fractions f{sub L}(K{sub 2}*{omega}) and f{sub L}(K{sub 2}*{phi}) to fix the phases {phi}{sub A}{sup VT} and {phi}{sub A}{sup TV}. (v) The experimental

Measurement of the eta-meson mass using psi(2S) --> etaJ/psi.

PubMed

Miller, D H; Sanghi, B; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Ge, J Y; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Artuso, M; Blusk, S; Khalil, S; Li, J; Menaa, N; Mountain, R; Nisar, S; Randrianarivony, K; Sia, R; Skwarnicki, T; Stone, S; Wang, J C; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Asner, D M; Edwards, K W; Naik, P; Briere, R A; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Adam, N E; Alexander, J P; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Athar, S B; Patel, R; Yelton, J; Rubin, P; Eisenstein, B I; Karliner, I; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A; Ernst, J; Ecklund, K M; Severini, H; Love, W; Savinov, V; Lopez, A; Mehrabyan, S; Mendez, H; Ramirez, J

2007-09-21

We measure the mass of the eta meson using psi(2S) --> etaJ/psi events acquired with the CLEO-c detector operating at the CESR e(+)e(-) collider. Using the four decay modes eta --> gamma gamma, 3pi(0), pi(+)pi(-)pi(0), and pi(+)pi(-)gamma, we find M(eta) = 547.785 +/- 0.017 +/- 0.057 MeV, in which the first uncertainty is statistical and the second systematic. This result has an uncertainty comparable to the two most precise previous measurements and is consistent with that of NA48, but is inconsistent at the level of 6.5 sigma with the much smaller mass obtained by GEM.

Central Exclusive $$\\pi^{+}\\pi^{-}$$ Production in $$p\\bar{p}$$ Collisions at $$\\sqrt{s} = 0.9$$ and 1.96 TeV at the Tevatron

DOE Office of Scientific and Technical Information (OSTI.GOV)

Žurek, Maria; Albrow, Michael

2014-01-01

Exclusivemore » $$\\pi^{+}\\pi^{-}$$ production in proton-antiproton collisions at $$\\sqrt{s} = 0.9$$ and 1.96 TeV in the Collider Detector at Fermilab has been measured. We selected events with exactly two particles with opposite charge, in $$|\\eta|<1.3$$, with no other particles detected in $$|\\eta| < 5.9$$. We require the central $$\\pi^{+}\\pi^{-}$$ to have rapidity $|y|<1$. Since these events are dominated by double pomeron exchange, the quantum numbers of the central state are constrained. The data show resonance structures attributed to the $$f_0$$ and $$f_2$$ mesons.« less

New measurement of exclusive decays of the {chi}{sub c0} and {chi}{sub c2} to two-meson final states

DOE Office of Scientific and Technical Information (OSTI.GOV)

Asner, D. M.; Edwards, K. W.; Reed, J.

2009-04-01

Using a sample of 2.59x10{sup 7} {psi}(2S) decays collected by the CLEO-c detector, we present results of a study of {chi}{sub c0} and {chi}{sub c2} decays into two-meson final states. We present the world's most precise measurements of the {chi}{sub cJ,(J=0,2)}{yields}{pi}{sup +}{pi}{sup -}, {pi}{sup 0}{pi}{sup 0}, K{sup +}K{sup -}, K{sub S}{sup 0}K{sub S}{sup 0}, {eta}{eta}, and {eta}{sup '}{eta}{sup '} branching fractions, and a search for {chi}{sub c} decays into {eta}{eta}{sup '}. These results shed light on the mechanism of charmonium decays into pseudoscalar mesons.

A new measurement of the rare decay eta -> pi^0 gamma gamma with the Crystal Ball/TAPS detectors at the Mainz Microtron

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nefkens, B M; Prakhov, S; Aguar-Bartolom��, P

2014-08-01

A new measurement of the rare, doubly radiative decay eta->pi^0 gamma gamma was conducted with the Crystal Ball and TAPS multiphoton spectrometers together with the photon tagging facility at the Mainz Microtron MAMI. New data on the dependence of the partial decay width, Gamma(eta->pi^0 gamma gamma), on the two-photon invariant mass squared, m^2(gamma gamma), as well as a new, more precise value for the decay width, Gamma(eta->pi^0 gamma gamma) = (0.33+/-0.03_tot) eV, are based on analysis of 1.2 x 10^3 eta->pi^0 gamma gamma decays from a total of 6 x 10^7 eta mesons produced in the gamma p -> etamore » p reaction. The present results for dGamma(eta->pi^0 gamma gamma)/dm^2(gamma gamma) are in good agreement with previous measurements and recent theoretical calculations for this dependence.« less

Measurement of absolute hadronic branching fractions of D mesons and e+e- -->DD cross sections at Ec.m.=3773 MeV.

PubMed

He, Q; Muramatsu, H; Park, C S; Park, W; Thorndike, E H; Coan, T E; Gao, Y S; Liu, F; Artuso, M; Boulahouache, C; Blusk, S; Butt, J; Dambasuren, E; Dorjkhaidav, O; Li, J; Menaa, N; Mountain, R; Nandakumar, R; Randrianarivony, K; Redjimi, R; Sia, R; Skwarnicki, T; Stone, S; Wang, J C; Zhang, K; Csorna, S E; Bonvicini, G; Cinabro, D; Dubrovin, M; Briere, R A; Chen, G P; Chen, J; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Adam, N E; Alexander, J P; Berkelman, K; Cassel, D G; Crede, V; Duboscq, J E; Ecklund, K M; Ehrlich, R; Fields, L; Gibbons, L; Gittelman, B; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Hsu, L; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Meyer, T O; Onyisi, P U E; Patterson, J R; Peterson, D; Phillips, E A; Pivarski, J; Riley, D; Ryd, A; Sadoff, A J; Schwarthoff, H; Shi, X; Shepherd, M R; Stroiney, S; Sun, W M; Urner, D; Weaver, K M; Wilksen, T; Weinberger, M; Athar, S B; Avery, P; Breva-Newell, L; Patel, R; Potlia, V; Stoeck, H; Yelton, J; Rubin, P; Cawlfield, C; Eisenstein, B I; Gollin, G D; Karliner, I; Kim, D; Lowrey, N; Naik, P; Sedlack, C; Selen, M; Williams, J; Wiss, J; Edwards, K W; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Gong, D T; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Li, S Z; Poling, R; Scott, A W; Smith, A; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A; Zweber, P; Ernst, J; Mahmood, A H; Severini, H; Asner, D M; Dytman, S A; Love, W; Mehrabyan, S; Mueller, J A; Savinov, V; Li, Z; Lopez, A; Mendez, H; Ramirez, J; Huang, G S; Miller, D H; Pavlunin, V; Sanghi, B; Shipsey, I P J; Adams, G S; Chasse, M; Cravey, M; Cummings, J P; Danko, I; Napolitano, J

2005-09-16

Using 55.8 pb(-1) of e+e- collisions recorded at the psi(3770) resonance with the CLEO-c detector at CESR, we determine absolute hadronic branching fractions of charged and neutral D mesons using a double tag technique. Among measurements for three D0 and six D+ modes, we obtain reference branching fractions B(D0-->K-pi+)=(3.91+/-0.08+/-0.09)% and B(D+-->K-pi+pi+)=(9.5+/-0.2+/-0.3)%, where the uncertainties are statistical and systematic, respectively. Final state radiation is included in these branching fractions by allowing for additional, unobserved, photons in the final state. Using a determination of the integrated luminosity, we also extract the cross sections sigma(e+e- -->D0D0)=(3.60+/-0.07(+0.07)(-0.05)) nb and sigma(e+e- -->D+D-)=(2.79+/-0.07(+0.10)(-0.04)) nb.

Sensitizing Triple-Negative Breast Cancer to PI3K Inhibition by Cotargeting IGF1R.

PubMed

de Lint, Klaas; Poell, Jos B; Soueidan, Hayssam; Jastrzebski, Katarzyna; Vidal Rodriguez, Jordi; Lieftink, Cor; Wessels, Lodewyk F A; Beijersbergen, Roderick L

2016-07-01

Targeted therapies have proven invaluable in the treatment of breast cancer, as exemplified by tamoxifen treatment for hormone receptor-positive tumors and trastuzumab treatment for HER2-positive tumors. In contrast, a subset of breast cancer negative for these markers, triple-negative breast cancer (TNBC), has met limited success with pathway-targeted therapies. A large fraction of TNBCs depend on the PI3K pathway for proliferation and survival, but inhibition of PI3K alone generally has limited clinical benefit. We performed an RNAi-based genetic screen in a human TNBC cell line to identify kinases whose knockdown synergizes with the PI3K inhibitor GDC-0941 (pictilisib). We discovered that knockdown of insulin-like growth factor-1 receptor (IGF1R) expression potently increased sensitivity of these cells to GDC-0941. Pharmacologic inhibition of IGF1R using OSI-906 (linsitinib) showed a strong synergy with PI3K inhibition. Furthermore, we found that the combination of GDC-0941 and OSI-906 is synergistic in 8 lines from a panel of 18 TNBC cell lines. In these cell lines, inhibition of IGF1R further decreases the activity of downstream PI3K pathway components when PI3K is inhibited. Expression analysis of the panel of TNBC cell lines indicates that the expression levels of IGF2BP3 can be used as a potential predictor for sensitivity to the PI3K/IGF1R inhibitor combination. Our data show that combination therapy consisting of PI3K and IGF1R inhibitors could be beneficial in a subset of TNBCs. Mol Cancer Ther; 15(7); 1545-56. ©2016 AACR. ©2016 American Association for Cancer Research.

Measurement of Inclusive Radiative B-Meson Decays with a Photon Energy Threshold of 1.7 GeV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Limosani, A.; Barberio, E.; Julius, T.

2009-12-11

Using 605 fb{sup -1} of data collected at the UPSILON(4S) resonance we present a measurement of the inclusive radiative B-meson decay channel, B->X{sub s}gamma. For the lower photon energy thresholds of 1.7, 1.8, 1.9, and 2.0 GeV, as defined in the rest frame of the B meson, we measure the partial branching fraction and the mean and variance of the photon energy spectrum. At the 1.7 GeV threshold we obtain the partial branching fraction BF(B->X{sub s}gamma)=(3.45+-0.15+-0.40)x10{sup -4}, where the errors are statistical and systematic.

Direct CP Violation in Charmless Hadronic B-Meson Decays at the PEP-II Asymmetric B-Meson Factory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Telnov, Alexandre Valerievich; /UC, Berkeley

2005-05-06

The study of the quark transition b {yields} s{bar s}s, which is a pure loop-level (''penguin'') process leading to several B-meson-decay final states, most notably {phi}K, is arguably the hottest topic in B-meson physics today. The reason is the sensitivity of the amplitudes and the CP-violating asymmetries in such processes to physics beyond the Standard Model. By performing these measurements, we improve our understanding of the phenomenon of combined-parity (CP) violation, which is believed to be responsible for the dominance of matter over antimatter in our Universe. Here, we present measurements of branching fractions and charge asymmetries in the decaysmore » B{sup +} {yields} {phi}K{sup +} and B{sup 0} {yields} {phi}K{sup 0} in a sample of approximately 89 million B{bar B} pairs collected by the BABAR detector at the PEP-II asymmetric-energy B-meson Factory at SLAC. We determine {Beta}(B{sup +} {yields} {phi}K{sup +}) = (10.0{sub -0.8}{sup +0.9} {+-} 0.5) x 10{sup -6} and {Beta}(B{sup 0} {yields} {phi}K{sup 0}) = (8.4{sub -1.3}{sup +1.5} {+-} 0.5) x 10{sup -6}, where the first error is statistical and the second is systematic. Additionally, we measure the CP-violating charge asymmetry {Alpha}{sub CP}(B{sup {+-}} {yields} {phi}K{sup {+-}}) = 0.04 {+-} 0.09 {+-} 0.01, with a 90% confidence-level interval of [-0.10, 0.18], and set an upper limit on the CKM- and color-suppressed decay B{sup +} {yields} {phi}{pi}{sup +}, {Beta}(B{sup +} {yields} {phi}{pi}{sup +}) < 0.41 x 10{sup -6} (at the 90% confidence level). Our results are consistent with the Standard Model, which predicts {Alpha}{sub CP}(B{sup {+-}} {yields} {phi}K{sup {+-}}) {approx}< 1% and {Beta}(B {yields} {phi}{tau}) << 10{sup -7}. Since many models of physics beyond the Standard Model introduce additional loop diagrams with new heavy particles and new CP-violating phases that would contribute to these decays, potentially making {Alpha}{sub CP} (B{sup {+-}} {yields} {phi}K{sup {+-}}) and {Beta

Two-pseudoscalar-meson decay of {chi}{sub cJ} with twist-3 corrections

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhou Mingzhen; Zhou Haiqing; Department of Physics, Southeast University, Nanjing 211189

2009-11-01

The decays of {chi}{sub cJ}{yields}{pi}{sup +}{pi}{sup -}, K{sup +}K{sup -} (J=0,2) are discussed within the standard and modified hard-scattering approach when including the contributions from twist-3 distribution amplitudes and wave functions of the light pseudoscalar meson. A model for twist-2 and twist-3 distribution amplitudes and wave functions of the pion and kaon with BHL prescription are proposed as the solution to the end-point singularities. The results show that the contributions from twist-3 parts are actually not power suppressed comparing with the leading-twist contribution. After including the effects from the transverse momentum of light meson valence-quark state and Sudakov factors, themore » decay widths of the {chi}{sub cJ} into pions or kaons are comparable with the their experimental data.« less

pi-eta mixing and charge symmetry violating NN potential in matter

DOE Office of Scientific and Technical Information (OSTI.GOV)

Biswas, Subhrajyoti; Roy, Pradip; Dutt-Mazumder, Abhee K.

2010-06-15

We construct density-dependent class III charge symmetry violating (CSV) potential caused by the mixing of pi-eta mesons with off-shell corrections. The density dependence enters through the nonvanishing pi-eta mixing driven by both the neutron-proton mass difference and their asymmetric density distribution. The contribution of density-dependent mixing to the CSV potential is found to be appreciably larger than that of the vacuum part.

Nuclear modification factor of D0 mesons in PbPb collisions at sqrt(s[NN]) = 5.02 TeV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sirunyan, Albert M; et al.

2017-08-16

The transverse momentum (pt) spectrum of prompt D0 mesons and their antiparticles has been measured via the hadronic decay channels D0 to K- pi+ and D0-bar to K+ pi- in pp and PbPb collisions at a centre-of-mass energy of 5.02 TeV per nucleon pair with the CMS detector at the LHC. The measurement is performed in the D0 meson pt range of 2-100 GeV and in the rapidity range of abs(y)<1. The pp (PbPb) dataset used for this analysis corresponds to an integrated luminosity of 27.4 inverse picobarns (530 inverse microbarns). The measured D0 meson pt spectrum in pp collisionsmore » is well described by perturbative QCD calculations. The nuclear modification factor, comparing D0 meson yields in PbPb and pp collisions, was extracted for both minimum-bias and the 10% most central PbPb interactions. For central events, the D0 meson yield in the PbPb collisions is suppressed by a factor of 5-6 compared to the pp reference in the pt range of 6-10 GeV. For D0 mesons in the high-pt range of 60-100 GeV, a significantly smaller suppression is observed. The results are also compared to theoretical calculations.« less

Absolute measurement of hadronic branching fractions of the Ds+ meson.

PubMed

Alexander, J P; Berkelman, K; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Riley, D; Ryd, A; Sadoff, A J; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Athar, S B; Patel, R; Yelton, J; Rubin, P; Eisenstein, B I; Karliner, I; Mehrabyan, S; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A; Libby, J; Powell, A; Wilkinson, G; Ecklund, K M; Love, W; Savinov, V; Lopez, A; Mendez, H; Ramirez, J; Ge, J Y; Miller, D H; Sanghi, B; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Artuso, M; Blusk, S; Khalil, S; Li, J; Mountain, R; Nisar, S; Randrianarivony, K; Sultana, N; Skwarnicki, T; Stone, S; Wang, J C; Zhang, L M; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Rademacker, J; Asner, D M; Edwards, K W; Naik, P; Briere, R A; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L

2008-04-25

The branching fractions of D(s)(+/-) meson decays serve to normalize many measurements of processes involving charm quarks. Using 298 pb(-1) of e(+)e(-) collisions recorded at a center of mass energy of 4.17 GeV, we determine absolute branching fractions for eight D(s)(+/-) decays with a double tag technique. In particular we determine the branching fraction B(D(s)(+)-->K(-)K(+}pi(+))=(5.50+/-0.23+/-0.16)%, where the uncertainties are statistical and systematic, respectively. We also provide partial branching fractions for kinematic subsets of the K(-)K(+)pi(+) decay mode.

Nuclear modification factor of D$^0$ mesons in PbPb collisions at $$\\sqrt{s_\\mathrm{NN}} = 5.02$$ TeV

DOE PAGES

Sirunyan, Albert M; et al.

2018-07-10

The transverse momentum (pt) spectrum of prompt D0 mesons and their antiparticles has been measured via the hadronic decay channels D0 to K- pi+ and D0-bar to K+ pi- in pp and PbPb collisions at a centre-of-mass energy of 5.02 TeV per nucleon pair with the CMS detector at the LHC. The measurement is performed in the D0 meson pt range of 2-100 GeV and in the rapidity range of abs(y)<1. The pp (PbPb) dataset used for this analysis corresponds to an integrated luminosity of 27.4 inverse picobarns (530 inverse microbarns). The measured D0 meson pt spectrum in pp collisionsmore » is well described by perturbative QCD calculations. The nuclear modification factor, comparing D0 meson yields in PbPb and pp collisions, was extracted for both minimum-bias and the 10% most central PbPb interactions. For central events, the D0 meson yield in the PbPb collisions is suppressed by a factor of 5-6 compared to the pp reference in the pt range of 6-10 GeV. For D0 mesons in the high-pt range of 60-100 GeV, a significantly smaller suppression is observed. The results are also compared to theoretical calculations.« less

Observation of CP violation in neutral B meson going to positive kaon-antipion and neutral B meson going to pion-antipion decays with the BABAR detector

NASA Astrophysics Data System (ADS)

Li, Xuanzhong

This dissertation describes the measurement of asymmetries in neutral B meson decays to two-body final states of charged pions and kaons. The results are obtained from a data sample of 383 million Upsilon(4 S) → BB¯ decays collected between 1999 and 2006 with the BABAR detector at the PEP-II asymmetric-energy B factory located at the Stanford Linear Accelerator Center, California. The maximum likelihood fit that incorporates kinematical, event-shape, and particle identification information is used to measure the CP asymmetries in B0 → pi +pi- and K+/- pi∓ decays. The direct CP-violating asymmetry between decays to K-pi + is AKpi = -0.107 +/- 0.018+0.007-0.004 . The time-dependent CP-violating parameters in B0 → pi+pi- decays are Spipi = -0.60 +/- 0.11 +/- 0.03, Cpipi = -0.21 +/- 0.09 +/- 0.02. For all the measurements above, the first error is statistical and the second is systematic.

Study of two-photon decays of pseudoscalar mesons via J /ψ radiative decays

NASA Astrophysics Data System (ADS)

Ablikim, M.; Achasov, M. N.; Ahmed, S.; Albrecht, M.; Amoroso, A.; An, F. F.; An, Q.; Bai, J. Z.; Bai, Y.; Bakina, O.; Baldini Ferroli, R.; Ban, Y.; Bennett, D. W.; Bennett, J. V.; Berger, N.; Bertani, M.; Bettoni, D.; Bian, J. M.; Bianchi, F.; Boger, E.; Boyko, I.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chai, J.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, J. C.; Chen, M. L.; Chen, P. L.; Chen, S. J.; Chen, X. R.; Chen, Y. B.; Chu, X. K.; Cibinetto, G.; Dai, H. L.; Dai, J. P.; Dbeyssi, A.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; de Mori, F.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Dou, Z. L.; Du, S. X.; Duan, P. F.; Fang, J.; Fang, S. S.; Fang, Y.; Farinelli, R.; Fava, L.; Fegan, S.; Feldbauer, F.; Felici, G.; Feng, C. Q.; Fioravanti, E.; Fritsch, M.; Fu, C. D.; Gao, Q.; Gao, X. L.; Gao, Y.; Gao, Y. G.; Gao, Z.; Garzia, I.; Goetzen, K.; Gong, L.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, Y. T.; Guo, A. Q.; Guo, R. P.; Guo, Y. P.; Haddadi, Z.; Han, S.; Hao, X. Q.; Harris, F. A.; He, K. L.; He, X. Q.; Heinsius, F. H.; Held, T.; Heng, Y. K.; Holtmann, T.; Hou, Z. L.; Hu, H. M.; Hu, T.; Hu, Y.; Huang, G. S.; Huang, J. S.; Huang, X. T.; Huang, X. Z.; Huang, Z. L.; Hussain, T.; Ikegami Andersson, W.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, X. S.; Jiang, X. Y.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Jin, Y.; Johansson, T.; Julin, A.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; Ke, B. C.; Khan, T.; Khoukaz, A.; Kiese, P.; Kliemt, R.; Koch, L.; Kolcu, O. B.; Kopf, B.; Kornicer, M.; Kuemmel, M.; Kuhlmann, M.; Kupsc, A.; Kühn, W.; Lange, J. S.; Lara, M.; Larin, P.; Lavezzi, L.; Leithoff, H.; Leng, C.; Li, C.; Li, Cheng; Li, D. M.; Li, F.; Li, F. Y.; Li, G.; Li, H. B.; Li, H. J.; Li, J. C.; Li, Jin; Li, K. J.; Li, Kang; Li, Ke; Li, Lei; Li, P. L.; Li, P. R.; Li, Q. Y.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. N.; Li, X. Q.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; Lin, D. X.; Liu, B.; Liu, B. J.; Liu, C. X.; Liu, D.; Liu, F. H.; Liu, Fang; Liu, Feng; Liu, H. B.; Liu, H. M.; Liu, Huanhuan; Liu, Huihui; Liu, J. B.; Liu, J. P.; Liu, J. Y.; Liu, K.; Liu, K. Y.; Liu, Ke; Liu, L. D.; Liu, P. L.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, Y. B.; Liu, Z. A.; Liu, Zhiqing; Long, Y. F.; Lou, X. C.; Lu, H. J.; Lu, J. G.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, T.; Luo, X. L.; Lyu, X. R.; Ma, F. C.; Ma, H. L.; Ma, L. L.; Ma, M. M.; Ma, Q. M.; Ma, T.; Ma, X. N.; Ma, X. Y.; Ma, Y. M.; Maas, F. E.; Maggiora, M.; Malik, Q. A.; Mao, Y. J.; Mao, Z. P.; Marcello, S.; Meng, Z. X.; Messchendorp, J. G.; Mezzadri, G.; Min, J.; Min, T. J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Morales Morales, C.; Muchnoi, N. Yu.; Muramatsu, H.; Musiol, P.; Mustafa, A.; Nefedov, Y.; Nerling, F.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Pan, Y.; Papenbrock, M.; Patteri, P.; Pelizaeus, M.; Pellegrino, J.; Peng, H. P.; Peters, K.; Pettersson, J.; Ping, J. L.; Ping, R. G.; Poling, R.; Prasad, V.; Qi, H. R.; Qi, M.; Qian, S.; Qiao, C. F.; Qin, J. J.; Qin, N.; Qin, X. S.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Richter, M.; Ripka, M.; Rong, G.; Rosner, Ch.; Sarantsev, A.; Savrié, M.; Schnier, C.; Schoenning, K.; Shan, W.; Shao, M.; Shen, C. P.; Shen, P. X.; Shen, X. Y.; Sheng, H. Y.; Song, J. J.; Song, W. M.; Song, X. Y.; Sosio, S.; Sowa, C.; Spataro, S.; Sun, G. X.; Sun, J. F.; Sun, L.; Sun, S. S.; Sun, X. H.; Sun, Y. J.; Sun, Y. K.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tang, C. J.; Tang, G. Y.; Tang, X.; Tapan, I.; Tiemens, M.; Tsednee, B.; Uman, I.; Varner, G. S.; Wang, B.; Wang, B. L.; Wang, D.; Wang, D. Y.; Wang, Dan; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, Meng; Wang, P.; Wang, P. L.; Wang, W. P.; Wang, X. F.; Wang, Y.; Wang, Y. D.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. Y.; Wang, Zongyuan; Weber, T.; Wei, D. H.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, L. J.; Wu, Z.; Xia, L.; Xia, Y.; Xiao, D.; Xiao, H.; Xiao, Y. J.; Xiao, Z. J.; Xie, Y. G.; Xie, Y. H.; Xiong, X. A.; Xiu, Q. L.; Xu, G. F.; Xu, J. J.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Yan, L.; Yan, W. B.; Yan, Y. H.; Yang, H. J.; Yang, H. X.; Yang, L.; Yang, Y. H.; Yang, Y. X.; Ye, M.; Ye, M. H.; Yin, J. H.; You, Z. Y.; Yu, B. X.; Yu, C. X.; Yu, J. S.; Yuan, C. Z.; Yuan, Y.; Yuncu, A.; Zafar, A. A.; Zeng, Y.; Zeng, Z.; Zhang, B. X.; Zhang, B. Y.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J.; Zhang, J. L.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, K.; Zhang, L.; Zhang, S. Q.; Zhang, X. Y.; Zhang, Y. H.; Zhang, Y. T.; Zhang, Yang; Zhang, Yao; Zhang, Yu; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, J. W.; Zhao, J. Y.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhou, Y. X.; Zhu, J.; Zhu, J.; Zhu, K.; Zhu, K. J.; Zhu, S.; Zhu, S. H.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zotti, L.; Zou, B. S.; Zou, J. H.; Besiii Collaboration

2018-04-01

Using a sample of 4.48 ×108 ψ (3686 ) events collected with the BESIII detector at the BEPCII collider, we study the two-photon decays of the pseudoscalar mesons π0, η , η', η (1405 ), η (1475 ), η (1760 ), and X (1835 ) in J /ψ radiative decays using ψ (3686 )→π+π-J /ψ events. The π0, η , and η' mesons are clearly observed in the two-photon mass spectra, and the branching fractions are determined to be B (J /ψ →γ π0→3 γ )=(3.57 ±0.12 ±0.16 )×10-5 , B (J /ψ →γ η →3 γ )=(4.42 ±0.04 ±0.18 )×10-4 , and B (J /ψ →γ η'→3 γ )=(1.26 ±0.02 ±0.05 )×10-4 , where the first error is statistical and the second is systematic. No clear signal for η (1405 ), η (1475 ), η (1760 ) or X (1835 ) is observed in the two-photon mass spectra, and upper limits at the 90% confidence level on the product branching fractions are obtained.

Study of two-photon decays of pseudoscalar mesons via J / ψ radiative decays

DOE PAGES

Ablikim, M.; Achasov, M. N.; Ahmed, S.; ...

2018-04-26

Using a sample of 4.48 × 10 8 ψ(3686) events collected with the BESIII detector at the BEPCII collider, we study the two-photon decays of the pseudoscalar mesons π⁰, η, η', η(1405), η(1475), η(1760), and X(1835) in J/ψ radiative decays using ψ(3686) → π⁺π⁻J/ψ events. The π⁰, η and η' mesons are clearly observed in the two-photon mass spectra, and the branching fractions are determined to be B(J/ψ → γπ⁰ → 3γ) = (3.57 ± 0.12 ± 0.16) × 10 -5, B(J/ψ → γη → 3γ) =(4.42 ± 0.04 ± 0.18) × 10 -4, and B(J/ψ → γη' → 3γ)more » = (1.26 ± 0.02 ± 0.05) × 10 -4, where the first errors are statistical and the second systematic. No clear signal for η(1405), η(1475), η(1760) or X(1835) is observed in the two-photon mass spectra, and upper limits at the 90% confidence level on the product branching fractions are obtained.« less

Study of two-photon decays of pseudoscalar mesons via J / ψ radiative decays

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ablikim, M.; Achasov, M. N.; Ahmed, S.

Using a sample of 4.48 × 10 8 ψ(3686) events collected with the BESIII detector at the BEPCII collider, we study the two-photon decays of the pseudoscalar mesons π⁰, η, η', η(1405), η(1475), η(1760), and X(1835) in J/ψ radiative decays using ψ(3686) → π⁺π⁻J/ψ events. The π⁰, η and η' mesons are clearly observed in the two-photon mass spectra, and the branching fractions are determined to be B(J/ψ → γπ⁰ → 3γ) = (3.57 ± 0.12 ± 0.16) × 10 -5, B(J/ψ → γη → 3γ) =(4.42 ± 0.04 ± 0.18) × 10 -4, and B(J/ψ → γη' → 3γ)more » = (1.26 ± 0.02 ± 0.05) × 10 -4, where the first errors are statistical and the second systematic. No clear signal for η(1405), η(1475), η(1760) or X(1835) is observed in the two-photon mass spectra, and upper limits at the 90% confidence level on the product branching fractions are obtained.« less

Photon and vector meson exchanges in the production of light meson pairs and elementary atoms

NASA Astrophysics Data System (ADS)

Gevorkyan, S. R.; Kuraev, E. A.; Volkov, M. K.

2013-01-01

The production of pseudoscalar and scalar meson pairs ππ, ηη, η‧η‧, σσ as well as bound states in high energy γγ collisions are considered. The exchange by a vector particle in the binary process γ + γ → ha + hb with hadronic states ha, hb in fragmentation regions of the initial particle leads to nondecreasing cross sections with increasing energy, that is a priority of peripheral kinematics. Unlike the photon exchange the vector meson exchange needs a reggeization leading to fall with energy growth. Nevertheless, due to the peripheral kinematics beyond very forward production angles the vector meson exchanges dominate over all possible exchanges. The proposed approach allows one to express the matrix elements of the considered processes through impacting factors, which can be calculated in perturbation models like chiral perturbation theory (ChPT) or the Nambu-Jona-Lasinio (NJL) model. In particular cases the impact factors can be determined from relevant γγ sub-processes or the vector meson radiative decay width. The pionium atom production in the collisions of high energy electrons and pions with protons is considered and the relevant cross sections have been estimated.

Branched-Chain Amino Acid Negatively Regulates KLF15 Expression via PI3K-AKT Pathway

PubMed Central

Liu, Yunxia; Dong, Weibing; Shao, Jing; Wang, Yibin; Zhou, Meiyi; Sun, Haipeng

2017-01-01

Recent studies have linked branched-chain amino acid (BCAA) with numerous metabolic diseases. However, the molecular basis of BCAA's roles in metabolic regulation remains to be established. KLF15 (Krüppel-like factor 15) is a transcription factor and master regulator of glycemic, lipid, and amino acids metabolism. In the present study, we found high concentrations of BCAA suppressed KLF15 expression while BCAA starvation induced KLF15 expression, suggesting KLF15 expression is negatively controlled by BCAA.Interestingly, BCAA starvation induced PI3K-AKT signaling. KLF15 induction by BCAA starvation was blocked by PI3K and AKT inhibitors, indicating the activation of PI3K-AKT signaling pathway mediated the KLF15 induction. BCAA regulated KLF15 expression at transcriptional level but not post-transcriptional level. However, BCAA starvation failed to increase the KLF15-promoter-driven luciferase expression, suggesting KLF15 promoter activity was not directly controlled by BCAA. Finally, fasting reduced BCAA abundance in mice and KLF15 expression was dramatically induced in muscle and white adipose tissue, but not in liver. Together, these data demonstrated BCAA negatively regulated KLF15 expression, suggesting a novel molecular mechanism underlying BCAA's multiple functions in metabolic regulation. PMID:29118722

Branched-Chain Amino Acid Negatively Regulates KLF15 Expression via PI3K-AKT Pathway.

PubMed

Liu, Yunxia; Dong, Weibing; Shao, Jing; Wang, Yibin; Zhou, Meiyi; Sun, Haipeng

2017-01-01

Recent studies have linked branched-chain amino acid (BCAA) with numerous metabolic diseases. However, the molecular basis of BCAA's roles in metabolic regulation remains to be established. KLF15 (Krüppel-like factor 15) is a transcription factor and master regulator of glycemic, lipid, and amino acids metabolism. In the present study, we found high concentrations of BCAA suppressed KLF15 expression while BCAA starvation induced KLF15 expression, suggesting KLF15 expression is negatively controlled by BCAA.Interestingly, BCAA starvation induced PI3K-AKT signaling. KLF15 induction by BCAA starvation was blocked by PI3K and AKT inhibitors, indicating the activation of PI3K-AKT signaling pathway mediated the KLF15 induction. BCAA regulated KLF15 expression at transcriptional level but not post-transcriptional level. However, BCAA starvation failed to increase the KLF15-promoter-driven luciferase expression, suggesting KLF15 promoter activity was not directly controlled by BCAA. Finally, fasting reduced BCAA abundance in mice and KLF15 expression was dramatically induced in muscle and white adipose tissue, but not in liver. Together, these data demonstrated BCAA negatively regulated KLF15 expression, suggesting a novel molecular mechanism underlying BCAA's multiple functions in metabolic regulation.

Measurement of the E Polarization Observable for yd --> pi^-p(p_s), yd-->K^0Lambda(p_s), and yd-->pi^+pi^-d(0) using CLAS g14 data at Jefferson Lab

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ho, Dao

Photoproduction of mesons from the nucleon has a long and ongoing tradition for exploring nucleon excitations and the baryon-baryon interaction. Polarization observables which play a role in the photoproduction mechanism are, therefore, essential in addition to the differential cross section. The CLAS collaboration at Jefferson Lab, has been active in measuring these observables, but until now only on a proton targets. However, a comprehensive picture of the pseudoscalar meson photoproduction requires neutron data as well. That is, paired measurements of observables in p and n reactions are necessary to disentangle the photoproduction mechanism on the basis of isospin I =more » 0, and I = 1 photo-coupling transition amplitudes. The g14 experiment with 'HDIce,' a longitudinally polarized solid target of molecular hydrogen-deuteride with low background contamination from other nuclear species, provided an unique opportunity to measure several polarization observables|for the first time|on the neutron for different channels. In particular, we present our measurements of the E beam-target polarization observable, which requires circularly polarized beam and a longitudinally polarized target, for p pi^-, K^0Lambda, and K^0Sigma^0 channels in the energy range of 1.5 lte W lte 2.3 GeV. In addition, we also utilized the g14 dataset to investigate the intrinsic spin of a possible dibaryonic ND bound state by measuring the E (beam-target) observable on the d-pi^+/-d channel of the reaction yd --> pi^+pi^-d(0). Finally, this thesis also discusses a highly efficient multivariate analysis method called Boosted Decision Trees, which we employed extensively for this work and which has not been used before in CLAS data analysis.« less

Search for glueballs

DOE Office of Scientific and Technical Information (OSTI.GOV)

Toki, W.

1997-06-01

In these Summer School lectures, the author reviews the results of recent glueball searches. He begins with a brief review of glueball phenomenology and meson spectroscopy, including a discussion of resonance behavior. The results on the f{sub o}(1500) and f{sub J}(1700) resonances from proton-antiproton experiments and radiative J/{Psi} decays are discussed. Finally, {pi}{pi} and {eta}{pi} studies from D{sub s} decays and exotic meson searches are reviewed. 46 refs., 40 figs.

Mended chiral symmetry and the linear sigma model in one-loop order

DOE Office of Scientific and Technical Information (OSTI.GOV)

Scadron, M.D.

1992-02-28

In this paper it is shown that the linear {sigma}-model in one loop order in the chiral limit recovers meson masses m{sub {pi}} = 0, m{sub {sigma}} = 2m{sub qk} (NJL), m {sub {rho}} = {radical}2 g{sub {rho}}f{pi} (KSRF), along with couplings g{sigma}{pi}{pi} = m{sup 2}{sub {sigma}}/2f{pi}, g{rho}{pi}{pi} = g{sub {rho}} (VMD universality) and Weinberg's mended chiral symmetry decay width relation {Gamma}{sub {sigma}} = (9/2){Gamma}{sub {rho}}. The linear {sigma}-model combined quark and meson loops also properly predict the radiative decays {pi}{sup 0} {yields} 2{gamma} {yields} e{nu}{gamma} and {delta}{sup 0} (983) {yields} 2{gamma}.

Measurement of sigma Lambda b0/sigma B0 x B(Lambda b0-->Lambda c+pi-)/B(B0-->D+pi-) in pp collisions at square root s=1.96 TeV.

PubMed

Abulencia, A; Adelman, J; Affolder, T; Akimoto, T; Albrow, M G; Ambrose, D; Amerio, S; Amidei, D; Anastassov, A; Anikeev, K; Annovi, A; Antos, J; Aoki, M; Apollinari, G; Arguin, J-F; Arisawa, T; Artikov, A; Ashmanskas, W; Attal, A; Azfar, F; Azzi-Bacchetta, P; Azzurri, P; Bacchetta, N; Badgett, W; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Baroiant, S; Bartsch, V; Bauer, G; Bedeschi, F; Behari, S; Belforte, S; Bellettini, G; Bellinger, J; Belloni, A; Benjamin, D; Beretvas, A; Beringer, J; Berry, T; Bhatti, A; Binkley, M; Bisello, D; Blair, R E; Blocker, C; Blumenfeld, B; Bocci, A; Bodek, A; Boisvert, V; Bolla, G; Bolshov, A; Bortoletto, D; Boudreau, J; Boveia, A; Brau, B; Brigliadori, L; Bromberg, C; Brubaker, E; Budagov, J; Budd, H S; Budd, S; Budroni, S; Burkett, K; Busetto, G; Bussey, P; Byrum, K L; Cabrera, S; Campanelli, M; Campbell, M; Canelli, F; Canepa, A; Carillo, S; Carlsmith, D; Carosi, R; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavalli-Sforza, M; Cerri, A; Cerrito, L; 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Wang, S M; Warburton, A; Waschke, S; Waters, D; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Wynne, S M; Yagil, A; Yamamoto, K; Yamaoka, J; Yamashita, T; Yang, C; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zaw, I; Zhang, X; Zhou, J; Zucchelli, S

2007-03-23

We present the first observation of the baryon decay Lambda b0-->Lambda c+pi- followed by Lambda c+-->pK-pi+ in 106 pb-1 pp collisions at square root s=1.96 TeV in the CDF experiment. In order to reduce systematic error, the measured rate for Lambda b0 decay is normalized to the kinematically similar meson decay B0-->D+pi- followed by D+-->pi+K-pi+. We report the ratio of production cross sections (sigma) times the ratio of branching fractions (B) for the momentum region integrated above pT>6 GeV/c and pseudorapidity range |eta|<1.3: sigma(pp-->Lambda b0X)/sigma(pp-->B0X)xB(Lambda b0-->Lambda c+pi-)/B(B0-->D+pi-)=0.82+/-0.08(stat)+/-0.11(syst)+/-0.22[B(Lambda c+-->pK-pi+)].

The use of Acoustic Radiation Force decorrelation-weighted pulse inversion (ADW-PI) for enhanced ultrasound contrast imaging

PubMed Central

Herbst, Elizabeth; Unnikrishnan, Sunil; Wang, Shiying; Klibanov, Alexander L.; Hossack, John A.; Mauldin, F. William

2016-01-01

Objectives The use of ultrasound imaging for cancer diagnosis and screening can be enhanced with the use of molecularly targeted microbubbles. Nonlinear imaging strategies such as pulse inversion (PI) and “contrast pulse sequences” (CPS) can be used to differentiate microbubble signal, but often fail to suppress highly echogenic tissue interfaces. This failure results in false positive detection and potential misdiagnosis. In this study, a novel Acoustic Radiation Force (ARF) based approach was developed for superior microbubble signal detection. The feasibility of this technique, termed ARF-decorrelation-weighted PI (ADW-PI), was demonstrated in vivo using a subcutaneous mouse tumor model. Materials and Methods Tumors were implanted in the hindlimb of C57BL/6 mice by subcutaneous injection of MC38 cells. Lipid-shelled microbubbles were conjugated to anti-VEGFR2 antibody and administered via bolus injection. An image sequence using ARF pulses to generate microbubble motion was combined with PI imaging on a Verasonics Vantage programmable scanner. ADW-PI images were generated by combining PI images with inter-frame signal decorrelation data. For comparison, CPS images of the same mouse tumor were acquired using a Siemens Sequoia clinical scanner. Results Microbubble-bound regions in the tumor interior exhibited significantly higher signal decorrelation than static tissue (n = 9, p < 0.001). The application of ARF significantly increased microbubble signal decorrelation (n = 9, p < 0.01). Using these decorrelation measurements, ADW-PI imaging demonstrated significantly improved microbubble contrast-to-tissue ratio (CTR) when compared to corresponding CPS or PI images (n = 9, p < 0.001). CTR improved with ADW-PI by approximately 3 dB compared to PI images and 2 dB compared to CPS images. Conclusions Acoustic radiation force can be used to generate adherent microbubble signal decorrelation without microbubble bursting. When combined with pulse inversion

Implications of R parity violating Yukawa couplings in {delta}S=1 semileptonic decays of K mesons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mir, Azeem; Tahir, Farida; Haseeb, Mahnaz Q.

2007-12-01

We present a class of constraints on products and combinations of Yukawa couplings for R parity violating (Re{sub p}) and lepton flavor conserving as well as violating semileptonic decays of K mesons into light pseudoscalar mesons along with two charged leptons at 1{sigma} and 2{sigma} levels. We compare the constraints obtained by semileptonic rare decays with pure leptonic rare decays and find that most of these bounds are now improved over the existing ones. We also study the forward-backward asymmetry in the decays of K{sup +}{yields}{pi}{sup +}l{sup +}l{sup -} (l=e and {mu}) in the absence of tensor terms. The asymmetrymore » is found to be up to O(10{sup -3}) (O(10{sup -1})) for the electron and muon modes, respectively. The asymmetry is found to be as large as O(10{sup -1}) in the case of K{sup +}{yields}{pi}{sup +}{mu}{sup +}{mu}{sup -}.« less

Neutral and charged scalar mesons, pseudoscalar mesons, and diquarks in magnetic fields

NASA Astrophysics Data System (ADS)

Liu, Hao; Wang, Xinyang; Yu, Lang; Huang, Mei

2018-04-01

We investigate both (pseudo)scalar mesons and diquarks in the presence of external magnetic field in the framework of the two-flavored Nambu-Jona-Lasinio (NJL) model, where mesons and diquarks are constructed by infinite sum of quark-loop chains by using random phase approximation. The polarization function of the quark-loop is calculated to the leading order of 1 /Nc expansion by taking the quark propagator in the Landau level representation. We systematically investigate the masses behaviors of scalar σ meson, neutral and charged pions as well as the scalar diquarks, with respect to the magnetic field strength at finite temperature and chemical potential. It is shown that the numerical results of both neutral and charged pions are consistent with the lattice QCD simulations. The mass of the charge neutral pion keeps almost a constant under the magnetic field, which is preserved by the remnant symmetry of QCD ×QED in the vacuum. The mass of the charge neutral scalar σ is around two times quark mass and increases with the magnetic field due to the magnetic catalysis effect, which is an typical example showing that the polarized internal quark structure cannot be neglected when we consider the meson properties under magnetic field. For the charged particles, the one quark-antiquark loop contribution to the charged π± increases essentially with the increase of magnetic fields due to the magnetic catalysis of the polarized quarks. However, the one quark-quark loop contribution to the scalar diquark mass is negative comparing with the point-particle result and the loop effect is small.

Infrared renormalons and single meson production in proton-proton collisions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ahmadov, A. I.; Aydin, Coskun; Hakan, Yilmaz A.

2009-07-01

In this article, we investigate the contribution of the higher-twist Feynman diagrams to the large-p{sub T} inclusive pion production cross section in proton-proton collisions and present the general formulas for the higher-twist differential cross sections in the case of the running coupling and frozen coupling approaches. The structure of infrared renormalon singularities of the higher-twist subprocess cross section and the resummed expression (the Borel sum) for it are found. We compared the resummed higher-twist cross sections with the ones obtained in the framework of the frozen coupling approach and leading-twist cross section. We obtain, that ratio R=({sigma}{sub {pi}{sup +}}{sup HT}){supmore » res}/({sigma}{sub {pi}{sup +}}{sup HT}){sup 0}, for all values of the transverse momentum p{sub T} of the pion identically equivalent to ratio r=({delta}{sub {pi}}{sup HT}){sup res}/({delta}{sub {pi}}{sup HT}){sup 0}. It is shown that the resummed result depends on the choice of the meson wave functions used in calculation. Phenomenological effects of the obtained results are discussed.« less

Measurement of CP--violating asymmetries in $$D^0\\to\\pi^+\\pi^-$$ and $$D^0\\to K^+K^-$$ decays at CDF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aaltonen, T.; /Helsinki Inst. of Phys.; Alvarez Gonzalez, B.

2011-11-01

We report on a measurement of CP-violating asymmetries (A{sub CP}) in the Cabibbo-suppressed D{sup 0} {yields} {pi}{sup +}{pi}{sup -} and D{sup 0} {yields} K{sup +}K{sup -} decays reconstructed in a data sample corresponding to 5.9 fb{sup -1} of integrated luminosity collected by the upgraded Collider Detector at Fermilab. We use the strong decay D*{sup +} {yields} D{sup 0}{pi}{sup +} to identify the flavor of the charmed meson at production and exploit CP-conserving strong c{bar c} pair-production in p{bar p} collisions. High-statistics samples of Cabibbo-favored D{sup 0} {yields} K{sup -}{pi}{sup +} decays with and without a D*{sup {+-}} tag are usedmore » to correct for instrumental effects and significantly reduce systematic uncertainties. We measure A{sub CP}(D{sup 0} {yields} {pi}{sup +}{pi}{sup -}) = (+0.22 {+-} 0.24(stat) {+-} 0.11 (syst))% and A{sub CP}(D{sup 0} {yields} K{sup +}K{sup -}) = (-0.24 {+-} 0.22 (stat) {+-} 0.09 (syst))%, in agreement with CP conservation. These are the most precise determinations from a single experiment to date. Under the assumption of negligible direct CP violation in D{sup 0} {yields} {pi}{sup +}{pi}{sup -} and D{sup 0} {yields} K{sup +}K{sup -} decays, the results provide an upper limit to the CP-violating asymmetry in D{sup 0} mixing, |A{sub CP}{sup ind}(D{sup 0})| < 0.13% at the 90% confidence level.« less

D*(s0)(2317) meson and D-meson-kaon scattering from lattice QCD.

PubMed

Mohler, Daniel; Lang, C B; Leskovec, Luka; Prelovsek, Sasa; Woloshyn, R M

2013-11-27

The scalar meson D*(s0)(2317) is found 37(17) MeV below the DK threshold in a lattice simulation of the J(P)=0(+) channel using, for the first time, both DK as well as s¯c interpolating fields. The simulation is done on N(f)=2+1 gauge configurations with m(π) is approximately equal to 156 MeV, and the resulting M(D*(s0))-1/4(M(D(s))+3M(D*(s)))=266(16) MeV is close to the experimental value 241.5(0.8) MeV. The energy level related to the scalar meson is accompanied by additional discrete levels due to DK scattering states. The levels near threshold lead to the negative DK scattering length a(0)=-1.33(20) fm that indicates the presence of a state below threshold.

Radiation Enhancement of Head and Neck Squamous Cell Carcinoma by the Dual PI3K/mTOR Inhibitor PF-05212384

PubMed Central

Leiker, Andrew J.; DeGraff, William; Choudhuri, Rajani; Sowers, Anastasia L.; Thetford, Angela; Cook, John A.; Van Waes, Carter; Mitchell, James B.

2015-01-01

Purpose Radiation remains a mainstay for the treatment of non-metastatic head and neck squamous cell carcinoma (HNSCC), a malignancy characterized by a high rate of PI3K/mTOR signaling axis activation. We investigated the ATP-competitive dual PI3K/mTOR inhibitor, PF-05212384, as a radiosensitizer in pre-clinical HNSCC models. Experimental Design Extent of radiation enhancement of two HNSCC cell lines (UMSCC1-wtP53, UMSCC46-mtP53) and normal human fibroblast (1522) was assessed by in vitro clonogenic assay with appropriate target inhibition verified by immunoblotting. Radiation induced DNA damage repair was evaluated by γH2AX western blots with mechanism of DNA-DSB repair abrogation investigated by cell cycle analysis, immunoblotting, and RT-PCR. PF-05212384 efficacy in vivo was assessed by UMSCC1 xenograft tumor regrowth delay, xenograft lysate immunoblotting, and tissue section immunohistochemistry. Results PF-05212384 effectively inhibited PI3K and mTOR resulting in significant radiosensitization of exponentially growing and plateau-phase cells with 24 hr treatment following irradiation, and variable radiation enhancement with 24 hr treatment prior to irradiation. Tumor cells radiosensitized to a greater extent than normal human fibroblasts. Post-irradiation PF-05212384 treatment delays γ-H2AX foci resolution. PF-05212384 24 hr exposure resulted in an evident G1/S phase block in p53 competent cells. Fractionated radiation plus IV PF-05212384 synergistically delayed nude-mice bearing UMSCC1 xenograft regrowth, with potential drug efficacy biomarkers identified, including pS6, pAkt, p4EBP1, and Ki67. Conclusions Taken together, our results of significant radiosensitization both in vitro and in vivo validates the PI3K/mTOR axis as a radiation modification target and PF-05212384 as a potential clinical radiation modifier of non-metastatic HNSCC. PMID:25724523

Negative regulatory role of PI3-kinase in TNF-induced tumor necrosis.

PubMed

Matschurat, Susanne; Blum, Sabine; Mitnacht-Kraus, Rita; Dijkman, Henry B P M; Kanal, Levent; De Waal, Robert M W; Clauss, Matthias

2003-10-20

Tissue factor is the prime initiator of blood coagulation. Expression of tissue factor in tumor endothelial cells leads to thrombus formation, occlusion of vessels and development of hemorrhagic infarctions in the tumor tissue, often followed by regression of the tumor. Tumor cells produce endogenous vascular endothelial growth factor (VEGF), which sensitizes endothelial cells for systemically administered tumor necrosis factor alpha (TNF alpha) and synergistically enhances the TNF-induced expression of tissue factor. We have analyzed the pathways involved in the induction of tissue factor in human umbilical cord vein endothelial cells (HUVECs) after combined stimulation with TNF and VEGF. By using specific low molecular weight inhibitors, we demonstrated that protein kinase C (PKC), p44/42 and p38 mitogen-activated protein (MAP) kinases, and stress-activated protein kinase (JNK) are essentially involved in the induction of tissue factor. In contrast, the application of wortmannin, an inhibitor of phosphatidylinositol 3 (PI3)-kinase, led to strongly enhanced expression of tissue factor in TNF- and VEGF-treated cells, implicating a negative regulatory role for PI3-kinase. In vivo, the application of wortmannin promoted the formation of TNF-induced hemorrhages and intratumoral necroses in murine meth A tumors. The co-injection of wortmannin lowered the effective dose of applied TNF. Therefore, it is conceivable that the treatment of TNF-sensitive tumors with a combination of TNF and wortmannin will ensure the selective damage of the tumor endothelium and minimize the risk of systemic toxicity of TNF. TNF-treatment in combination with specific inhibition of PI3-kinase is a novel concept in anti-cancer therapy. Copyright 2003 Wiley-Liss, Inc.

Search for popcorn mesons in events with two charmed baryons

NASA Astrophysics Data System (ADS)

Hartfiel, Brandon

The physics of this dissertation is divided into two parts. The first part measures the Λc → pi kp continuum momentum spectrum at a center of mass energy of 10.54 GeV/c, which is just below the Υ(4s) resonance. The data sample consists of 15,400 Λc baryons from 9.46 fb-1 of integrated luminosity collected with the BaBar detector at the PEP-II asymmetric B factory at the Stanford Linear Accelerator Center. With more than 13 times more data than the best previous measurement, we are able to exclude some of the simpler, one parameter fragmentation functions. In the second part, we add the Λc → K0p mode, and look for events with a Λc+ and a Λ c- in order to look for "popcorn" mesons formed between the baryon and antibaryon. We add on-resonance data, with a kinematic cut to eliminate background from B decays, as well as BaBar run 3 and 4 data to increase the total data size to 219.70 fb-1. We find 619 events after background subtraction. After a subtraction of 1.06+/-.09 charged pions coming from decays of known resonances to Λc + npi, we are left with 2.63+/-.21 additional charged pious in each of these events. This is significantly higher than the .5 popcorn mesons per bayon pair used in the current tuning of Pythia 6.2, the most widely used Monte Carlo generator. The extra mesons we find appear to be the first direct evidence of popcorn mesons, although some of them could be arising from hypothetical unresolved, unobserved charmed baryon resonances contributing decay mesons to our data. To contribute a significant fraction, this hypothesis requires a large number of such broad unresolved states and seems unlikely, but can not be completely excluded.

Characteristics of the Hadronic Production of the $$D^{*\\pm}$$ Meson (in Portuguese)

DOE Office of Scientific and Technical Information (OSTI.GOV)

de Miranda, Jussara Marques

The Fermilab experiment E769, a 250 GeV /c tagged hadron beam incident on thin target foils of Be, Al,Cu, and W, measured themore » $$X_F$$ and $$p^2_t$$ distributions of $$D^{*\\pm}$$ through the decay mode$$D^{*\\pm} \\to D^0 \\pi^+, D^0 \\to K^- \\pi^+$$. Fitting the distributions to the form $$A(1 - X_F)^n$$ and $$B exp(-bp^2_t)$$, we determined $n$ - 3.84 ± 0.20 ± 0.06 and $b$ = 0. 7 48 ± 0.034 ± 0.009, respectively. We observe no significant lea.ding particle ef.~ct suggested by earlier experiments. The dependence of the total cross section on the atomic mass number was determined to be $$A^{0.98 \\pm 0,05 \\pm 0.04}$$ . The measurements were based on 351 ± 16 fully reconstructed $$D^{*\\pm}$$ mesons induced by a $$\\pi^{\\pm}$$ and $$K^{\\pm}$$ beam. This is the gest available sample of hadroproduced $$D^{*\\pm}$$.« less

Measurement of the branching ratio of a rare decay {eta}{yields}{pi}{sup 0}{gamma}{gamma} with WASA-at-COSY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lalwani, Kavita

2011-10-24

In this paper we present the preliminary results on the measurement of the branching ratio of a rare decay {eta}{yields}{pi}{sup 0}{gamma}{gamma} with the WASA Detector at COSY. We have used a sample of 10{sup 7}{eta} mesons produced at the COSY ring using the pd{yields}{sup 3}He{eta} reaction close to threshold. We detail the intricate extraction of the signal, which has about 360{+-}70(stat){eta}{yields}{pi}{sup 0}{gamma}{gamma} events, from the overwhelming background channels for example {eta}{yields}3{pi}{sup 0}, pd{yields}{sup 3}He 3{pi}{sup 0} and pd{yields}{sup 3}He 2{pi}{sup 0}.

THE ANGULAR DISTRIBUTION OF POSITRONS IN $pi$$sup +$-$mu$$sup +$-e$sup +$ DECAY IN PROPANE (in Russian)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alikhanyan, A.I.; Kirillov-Ugryumov, V.G.; Kotenko, L.P.

1958-01-01

In consideration of the wide use of propane bubble cameras, investigations were made of the angular distribution of electrons from pi /sup +/ -- mu /sup +/--e/sup +/ decay in propane to determine the possibility of using propane in angular correlation measurements of processes simlar to mu --e decay. The scheme of the experiment made with a bubble chamber of (7.2 x 6.5 x 16)cm/ dmensions bombarded by a 175-Mev pi -meson beam from a phasotron is described. (R.V.J.)

PTEN, a negative regulator of PI3K/Akt signaling, sustains brain stem cardiovascular regulation during mevinphos intoxication.

PubMed

Tsai, Ching-Yi; Wu, Jacqueline C C; Fang, Chi; Chang, Alice Y W

2017-09-01

Activation of PI3K/Akt signaling, leading to upregulation of nitric oxide synthase II (NOS II)/peroxynitrite cascade in the rostral ventrolateral medulla (RVLM), the brain stem site that maintains blood pressure and sympathetic vasomotor tone, underpins cardiovascular depression induced by the organophosphate pesticide mevinphos. By exhibiting dual-specificity protein- and lipid-phosphatase activity, phosphatase and tensin homolog (PTEN) directly antagonizes the PI3K/Akt signaling by dephosphorylation of phosphatidylinositol-3,4,5-trisphosphate, the lipid product of PI3K. Based on the guiding hypothesis that PTEN may sustain brain stem cardiovascular regulation during mevinphos intoxication as a negative regulator of PI3K/Akt signaling in the RVLM, we aimed in this study to clarify the mechanistic role of PTEN in mevinphos-induced circulatory depression. Microinjection bilaterally of mevinphos (10 nmol) into the RVLM of anesthetized Sprague-Dawley rats induced a progressive hypotension and a decrease in baroreflex-mediated sympathetic vasomotor tone. There was progressive augmentation in PTEN activity as reflected by a decrease in the oxidized form of PTEN in the RVLM during mevinhpos intoxication, without significant changes in the mRNA or protein level of PTEN. Loss-of-function manipulations of PTEN in the RVLM by immunoneutralization, pharmacological blockade or siRNA pretreatment significantly potentiated the increase in Akt activity or NOS II/peroxynitrite cascade in the RVLM, enhanced the elicited hypotension and exacerbated the already reduced baroreflex-mediated sympathetic vasomotor tone. We conclude that augmented PTEN activity via a decrease of its oxidized form in the RVLM sustains brain stem cardiovascular regulation during mevinphos intoxication via downregulation of the NOS II/peroxynitrite cascade as a negative regulator of PI3K/Akt signaling. Copyright © 2017 Elsevier Ltd. All rights reserved.

Observation of the rare decay B{sup +}{yields}K{sup +}{pi}{sup 0}{pi}{sup 0} and measurement of the quasi-two-body contributions B{sup +}{yields}K*(892){sup +}{pi}{sup 0}, B{sup +}{yields}f{sub 0}(980)K{sup +}, and B{sup +}{yields}{chi}{sub c0}K{sup +}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lees, J. P.; Poireau, V.; Tisserand, V.

We report an analysis of charmless hadronic decays of charged B mesons to the final state K{sup +}{pi}{sup 0}{pi}{sup 0}, using a data sample of (470.9{+-}2.8)x10{sup 6} BB events collected with the BABAR detector at the {Upsilon}(4S) resonance. We observe an excess of signal events, with a significance above 10 standard deviations including systematic uncertainties, and measure the branching fraction and CP asymmetry to be B(B{sup +}{yields}K{sup +}{pi}{sup 0}{pi}{sup 0})=(16.2{+-}1.2{+-}1.5)x10{sup -6} and A{sub CP}(B{sup +}{yields}K{sup +}{pi}{sup 0}{pi}{sup 0})=-0.06{+-}0.06{+-}0.04, where the uncertainties are statistical and systematic, respectively. Additionally, we study the contributions of the B{sup +}{yields}K{sup *}(892){sup +}{pi}{sup 0}, B{sup +}{yields}f{submore » 0}(980)K{sup +}, and B{sup +}{yields}{chi}{sub c0}K{sup +} quasi-two-body decays. We report the world's best measurements of the branching fraction and CP asymmetry of the B{sup +}{yields}K{sup +}{pi}{sup 0}{pi}{sup 0} and B{sup +}{yields}K{sup *}(892){sup +}{pi}{sup 0} channels.« less

Study of Orbitally Excited $$B_{(s)}$$ Mesons and Evidence for a New $$B\\pi$$ Resonance with the CDF II Detector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kambeitz, Manuel

This thesis presents an analysis of excited states of B0, B+ and B0 s mesons, decaying to B mesons while emitting a pion or kaon. They are reconstructed from their decay products and a selection is performed to discard wrongly reconstructed B(s) mesons with the multivariate analysis software NeuroBayes, as described in chapter 5. In the training process, the sPlot method and measured and simulated data are used. Chapter 6 describes how the properties of excited B(s) are determined by an unbinned maximum likelihood t to their mass spectra. The systematic uncertainties determined in this analysis are described in chaptermore » 7. The results of this thesis are presented in chapter 8 and a conclusion is given in chapter 9. The results shown in this thesis have been published before in [1].« less

Dalitz Plot Analyses of B- to D+ Pi- Pi-, B+ to Pi+ Pi- Pi+ and D(S)+ to Pi+ Pi- Pi+ at BaBar

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dong, Liaoyuan; /Iowa State U.

We report on the Dalitz plot analyses of B{sup -} {yields} D{sup +}{pi}{sup -}{pi}{sup -}, B{sup +} {yields} {pi}{sup +}{pi}{sup -}{pi}{sup +} and D{sub s}{sup +} {yields} {pi}{sup +}{pi}{sup -}{sup +}. The Dalitz plot method and the most recent BABAR results are discussed.

{phi} meson production in pp annihilation at rest

DOE Office of Scientific and Technical Information (OSTI.GOV)

Srisuphaphon, S.; Yan, Y.; Thailand Center of Excellence in Physics, Ministry of Education, Bangkok

2011-10-01

Apparent channel-dependent violations of the Okubo-Zwieg-Iizuka (OZI) rule in nucleon-antinucleon annihilation reactions in the presence of an intrinsic strangeness component in the nucleon are discussed. Admixture of ss quark pairs in the nucleon wave function enables the direct coupling to the {phi}-meson in the annihilation channel without violating the OZI rule. Three forms are considered in this work for the strangeness content of the proton wave function, namely, the uud cluster with a ss sea-quark component, kaon-hyperon clusters based on a simple chiral quark model, and the pentaquark picture uudss. Nonrelativistic quark model calculations reveal that the strangeness magnetic momentmore » {mu}{sub s} and the strangeness contribution to the proton spin {sigma}{sub s} from the first two models are consistent with recent experimental data, where {mu}{sub s} and {sigma}{sub s} are negative. For the third model, the uuds subsystem with the configurations [31]{sub FS}[211]{sub F}[22]{sub S} and [31]{sub FS}[31]{sub F}[22]{sub S} leads to negative values of {mu}{sub s} and {sigma}{sub s}. With effective quark line diagrams incorporating the {sup 3}P{sub 0} model, we give estimates for the branching ratios of the annihilation reactions at rest pp{yields}{phi}X (X={pi}{sup 0}, {eta}, {rho}{sup 0}, {omega}). Results for the branching ratios of {phi}X production from atomic pp s-wave states are for the first and third model found to be strongly channel dependent, in good agreement with measured rates.« less

Vector- and tensor-meson production and the Pomeron-f identity hypothesis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, S.T.

Within the context of a model introduced some time ago, the differential and total production cross sections for vector and tensor mesons are shown to be compatible with the hypothesis that the Pomeron and f are a single Regge trajectory. The model incorporates both cylinder and flavoring renormalizations of the Pomeron-f trajectory. The processes K/sup +- /p..-->..K/sup */(892)/sup +- /p, K/sup +- /p ..-->..K/sub 2//sup */(1430)/sup +- /p, and ..pi../sup +- /p..-->..A/sub 2/(1320)/sup +- /p are analyzed in some detail.

PiVoT GPS Receiver

NASA Technical Reports Server (NTRS)

Wennersten, Miriam Dvorak; Banes, Anthony Vince; Boegner, Gregory J.; Dougherty, Lamar; Edwards, Bernard L.; Roman, Joseph; Bauer, Frank H. (Technical Monitor)

2001-01-01

NASA Goddard Space Flight Center has built an open architecture, 24 channel space flight GPS receiver. The CompactPCI PiVoT GPS receiver card is based on the Mitel/GEC Plessey Builder-2 board. PiVoT uses two Plessey 2021 correlators to allow tracking of up to 24 separate GPS SV's on unique channels. Its four front ends can support four independent antennas, making it a useful card for hosting GPS attitude determination algorithms. It has been built using space quality, radiation tolerant parts. The PiVoT card will track a weaker signal than the original Builder 2 board. It also hosts an improved clock oscillator. The PiVoT software is based on the original Plessey Builder 2 software ported to the Linux operating system. The software is POSIX complaint and can easily be converted to other POSIX operating systems. The software is open source to anyone with a licensing agreement with Plessey. Additional tasks can be added to the software to support GPS science experiments or attitude determination algorithms. The next generation PiVoT receiver will be a single radiation hardened CompactPCI card containing the microprocessor and the GPS receiver optimized for use above the GPS constellation. PiVoT was flown successfully on a balloon in July, 2001, for its first non-simulated flight.

Peculiarities of biological action of hadrons of space radiation.

PubMed

Akoev, I G; Yurov, S S

1975-01-01

Biological investigations in space enable one to make a significant contribution on high-energy hadrons to biological effects under the influence of factors of space flights. Physical and molecular principles of the action of high-energy hadrons are analysed. Genetic and somatic hadron effects produced by the secondary radiation from 70 GeV protons have been studied experimentally. The high biological effectiveness of hadrons, great variability in biological effects, and specifically of their action, are associated with strong interactions of high-energy hadrons. These are the probability of nuclear interaction with any atom nucleus, generation of a great number of secondary particles (among them, probably, highly effective multicharged and heavy nuclei, antiprotons, pi(-)-mesons), and the spatial distribution of secondary particles as a narrow cone with extremely high density of particles in its first part. The secondary radiation generated by high- and superhigh-energy hadrons upon their interaction with the spaceship is likely to be the greatest hazard of radiation to the crew during space flights.

σ and κ mesons as broad dynamical resonances in one-meson-exchange model

NASA Astrophysics Data System (ADS)

Hong Xiem, Ngo Thi; Shinmura, Shoji

2014-09-01

The existences of broad scalar σ (600) and κ (700) mesons have been discussed intensively in the experimental and theoretical studies on ππ and πK scatterings. By using chiral perturbation model, J. Oller, A. Gómez and J. R. Peláez confirmed the existence of these mesons as dynamical resonances. In meson-exchange models, their existence has not been established yet. In this talk, using the quasi-potential of meson-exchange model and Lippmann-Schwinger equation, we determine the T and S-matrices, from which we could find the positions of poles in physical amplitudes in the complex E-plane. With the full treatment of meson-meson interactions (ππ - πK - πη - ηη and πK - ηK) , for the first time, the existence of the scalar σ (600) and κ (700) mesons are confirmed in one-meson-exchange model. There are two kinds of form factors in our model: the monopole and the Gaussian. Our recent results show that the poles σ and κ appear at around 410 - i 540 MeV and 650 - i 20 MeV for monopole form factors, respectively. For Gaussian form factors, the poles σ and κ, respectively, are at 360 - i 510 MeV and 649 - i 190 MeV.

PiVoT GPS Receiver

NASA Technical Reports Server (NTRS)

Wennersten, Miriam; Banes, Vince; Boegner, Greg; Clagnett, Charles; Dougherty, Lamar; Edwards, Bernard; Roman, Joe; Bauer, Frank H. (Technical Monitor)

2001-01-01

NASA Goddard Space Flight Center has built an open architecture, 24 channel spaceflight Global Positioning System (GPS) receiver. The compact PCI PiVoT GPS receiver card is based on the Mitel/GEC Plessey Builder 2 board. PiVoT uses two Plessey 2021 correlators to allow tracking of up to 24 separate GPS SV's on unique channels. Its four front ends can support four independent antennas, making it a useful card for hosting GPS attitude determination algorithms. It has been built using space quality, radiation tolerant parts. The PiVoT card works at a lower signal to noise ratio than the original Builder 2 board. It also hosts an improved clock oscillator. The PiVoT software is based on the original Piessey Builder 2 software ported to the Linux operating system. The software is posix compliant and can be easily converted to other posix operating systems. The software is open source to anyone with a licensing agreement with Plessey. Additional tasks can be added to the software to support GPS science experiments or attitude determination algorithms. The next generation PiVoT receiver will be a single radiation hardened compact PCI card containing the microprocessor and the GPS receiver optimized for use above the GPS constellation.

Phosphatidylinositide 3-kinase (PI3K) and PI3K-related kinase (PIKK) activity contributes to radioresistance in thyroid carcinomas.

PubMed

Burrows, Natalie; Williams, Joseph; Telfer, Brian A; Resch, Julia; Valentine, Helen R; Fitzmaurice, Richard J; Eustace, Amanda; Irlam, Joely; Rowling, Emily J; Hoang-Vu, Cuong; West, Catharine M; Brabant, Georg; Williams, Kaye J

2016-09-27

Anaplastic (ATC) and certain follicular thyroid-carcinomas (FTCs) are radioresistant. The Phosphatidylinositide 3-kinase (PI3K) pathway is commonly hyperactivated in thyroid-carcinomas. PI3K can modify the PI3K-related kinases (PIKKs) in response to radiation: How PIKKs interact with PI3K and contribute to radioresistance in thyroid-carcinomas is unknown. Further uncertainties exist in how these interactions function under the radioresistant hypoxic microenvironment. Under normoxia/anoxia, ATC (8505c) and FTC (FTC-133) cells were irradiated, with PI3K-inhibition (via GDC-0941 and PTEN-reconstitution into PTEN-null FTC-133s) and effects on PIKK-activation, DNA-damage, clonogenic-survival and cell cycle, assessed. FTC-xenografts were treated with 5 × 2 Gy, ± 50 mg/kg GDC-0941 (twice-daily; orally) for 14 days and PIKK-activation and tumour-growth assessed. PIKK-expression was additionally assessed in 12 human papillary thyroid-carcinomas, 13 FTCs and 12 ATCs. GDC-0941 inhibited radiation-induced activation of Ataxia-telangiectasia mutated (ATM), ATM-and Rad3-related (ATR) and DNA-dependent protein kinase catalytic subunit (DNA-PKcs). Inhibition of ATM and DNA-PKcs was PI3K-dependent, since activation was reduced in PTEN-reconstituted FTC-133s. Inhibition of PIKK-activation was greater under anoxia: Consequently, whilst DNA-damage was increased and prolonged under both normoxia and anoxia, PI3K-inhibition only reduced clonogenic-survival under anoxia. GDC-0941 abrogated radiation-induced cell cycle arrest, an effect most likely linked to the marked inhibition of ATR-activation. Importantly, GDC-0941 inhibited radiation-induced PIKK-activation in FTC-xenografts leading to a significant increase in time taken for tumours to triple in size: 26.5 ± 5 days (radiation-alone) versus 31.5 ± 5 days (dual-treatment). PIKKs were highly expressed across human thyroid-carcinoma classifications, with ATM scoring consistently lower. Interestingly, some loss of ATM and DNA

Phosphatidylinositide 3-kinase (PI3K) and PI3K-related kinase (PIKK) activity contributes to radioresistance in thyroid carcinomas

PubMed Central

Burrows, Natalie; Williams, Joseph; Telfer, Brian A; Resch, Julia; Valentine, Helen R; Fitzmaurice, Richard J; Eustace, Amanda; Irlam, Joely; Rowling, Emily J; Hoang-Vu, Cuong; West, Catharine M; Brabant, Georg; Williams, Kaye J

2016-01-01

Anaplastic (ATC) and certain follicular thyroid-carcinomas (FTCs) are radioresistant. The Phosphatidylinositide 3-kinase (PI3K) pathway is commonly hyperactivated in thyroid-carcinomas. PI3K can modify the PI3K-related kinases (PIKKs) in response to radiation: How PIKKs interact with PI3K and contribute to radioresistance in thyroid-carcinomas is unknown. Further uncertainties exist in how these interactions function under the radioresistant hypoxic microenvironment. Under normoxia/anoxia, ATC (8505c) and FTC (FTC-133) cells were irradiated, with PI3K-inhibition (via GDC-0941 and PTEN-reconstitution into PTEN-null FTC-133s) and effects on PIKK-activation, DNA-damage, clonogenic-survival and cell cycle, assessed. FTC-xenografts were treated with 5 × 2 Gy, ± 50 mg/kg GDC-0941 (twice-daily; orally) for 14 days and PIKK-activation and tumour-growth assessed. PIKK-expression was additionally assessed in 12 human papillary thyroid-carcinomas, 13 FTCs and 12 ATCs. GDC-0941 inhibited radiation-induced activation of Ataxia-telangiectasia mutated (ATM), ATM-and Rad3-related (ATR) and DNA-dependent protein kinase catalytic subunit (DNA-PKcs). Inhibition of ATM and DNA-PKcs was PI3K-dependent, since activation was reduced in PTEN-reconstituted FTC-133s. Inhibition of PIKK-activation was greater under anoxia: Consequently, whilst DNA-damage was increased and prolonged under both normoxia and anoxia, PI3K-inhibition only reduced clonogenic-survival under anoxia. GDC-0941 abrogated radiation-induced cell cycle arrest, an effect most likely linked to the marked inhibition of ATR-activation. Importantly, GDC-0941 inhibited radiation-induced PIKK-activation in FTC-xenografts leading to a significant increase in time taken for tumours to triple in size: 26.5 ± 5 days (radiation-alone) versus 31.5 ± 5 days (dual-treatment). PIKKs were highly expressed across human thyroid-carcinoma classifications, with ATM scoring consistently lower. Interestingly, some loss of ATM and DNA

[pi][sup 0] electromagnetic self-energy and its implications for incorporating electromagnetism in few-body systems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maltman, K.

1994-08-01

By investigating the electromagnetic (EM) chiral series for the pseudoscalar mesons at next-to-leading order, it is shown that the [pi][sup 0] EM self-energy is [ital O]([alpha][sub EM][ital m][sub [ital u],][ital d]), and hence small. This observation completes the crucial step in an earlier argument, which employed previously the vanishing of the [pi][sup 0] EM self-energy in the chiral limit, and which demonstrates that the effects of not only one-photon-exchange- but also one-photon-loop graphs must be included in order to incorporate the effects of electromagnetism in hadronic systems.

Charm radiative decays with neutral mesons D 0→ K¯0π 0γ , D 0→ K¯0η(η‧)γ

NASA Astrophysics Data System (ADS)

Fajfer, S.; Prapotnik, A.; Singer, P.

2002-12-01

The radiative decays D0→K¯0P0γ with nonresonant K¯0P0 (P0=π0,η,η‧) are considered within the framework which combines heavy quark effective theory and the chiral Lagrangian. Due to neutral mesons the amplitudes do not have bremsstrahlung contributions. We assume factorization for the weak matrix elements. Light (virtual) vector mesons are found to give the main contribution to the decay amplitudes. The decay D0→K¯0π0γ is predicted to have a branching ratio of 3×10-4, with comparable contributions from parity-conserving and parity-violating parts of the amplitude. The decays with η(η‧) in the final state are expected with branching ratios of 1.1×10-5 and 0.4×10-7, respectively, and are mainly parity conserving.

Impact on photon/phi 3 meson measurement from CLEO-c binned neutral D meson decaying to neutral kaon(short,long) positive pion negative pion Dalitz analysis

NASA Astrophysics Data System (ADS)

He, Qing

The Dalitz plot analysis of the three-body decay D˜0 → K0S pi+pi-- (D0 or D0) from the B+/- → DK+/- process provides today the best measurement of the CKM angle gamma/φ3. However, the unbinned D˜0 → K0S Dalitz analysis is sensitive to the choice of the model used to describe the three-body decay, which introduces 7° ˜ 10° uncertainty on gamma determination. For LHCb and future Super-B factories, this uncertainty will become a major limitation. A model independent approach has been proposed and the quantum correlated D0/ D0 data produced at the resonance psi(3770) can provide important information on the strong phase difference between D 0 → K0S pi+pi-- and D 0 → K0S pi+pi-- processes. Using the 818 pb-1 data collected by the CLEO-c detector at the Cornell Electron Storage Ring, we measure the strong phase parameters, c i, si, using fully reconstructed D0 D0 pairs with K0S pi+pi-- vs. flavor states, CP eigenstates and double K0S pi+pi-- samples. We also include K0L pi+pi-- data to further improve the determination of ci and si in a global fit. The ci and si results for the 8 phase bin case are shown in the following table. With the ci, si measurements from CLEO, the uncertainty of gamma determination can be lowered down to about 2° if one assumes plenty of B+/- → D˜K +/- decays.* *Please refer to dissertation for diagrams.

Measurement of time-dependent CP asymmetries and constraints on sin(2beta+gamma) with partial reconstruction of B0-->D*-/+pi+/- decays.

PubMed

Aubert, B; Barate, R; Boutigny, D; Couderc, F; Gaillard, J-M; Hicheur, A; Karyotakis, Y; Lees, J P; Robbe, P; Tisserand, V; Zghiche, A; Palano, A; Pompili, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Day, C T; Gill, M S; Gritsan, A V; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; LeClerc, C; Levi, M E; Lynch, G; Mir, L M; Oddone, P J; Orimoto, T J; Pripstein, M; Roe, N A; Romosan, A; Ronan, M T; Shelkov, V G; Telnov, A V; Wenzel, W A; Ford, K; Harrison, T J; Hawkes, C M; Knowles, D J; Morgan, S E; Penny, R C; Watson, A T; Watson, N K; Goetzen, K; Held, T; Koch, H; Lewandowski, B; Pelizaeus, M; Peters, K; Schmuecker, H; Steinke, M; Boyd, J T; Chevalier, N; Cottingham, W N; Kelly, M P; Latham, T E; Mackay, C; Wilson, F F; Abe, K; Cuhadar-Donszelmann, T; Hearty, C; Mattison, T S; McKenna, J A; Thiessen, D; Kyberd, P; McKemey, A K; Teodorescu, L; Blinov, V E; Bukin, A D; Golubev, V B; Ivanchenko, V N; Kravchenko, E A; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Yushkov, A N; Best, D; Bruinsma, M; Chao, M; Kirkby, D; Lankford, A J; Mandelkern, M; Mommsen, R K; Roethel, W; Stoker, D P; Buchanan, C; Hartfiel, B L; Gary, J W; Layter, J; Shen, B C; Wang, K; del Re, D; Hadavand, H K; Hill, E J; MacFarlane, D B; Paar, H P; Rahatlou, Sh; Sharma, V; Berryhill, J W; Campagnari, C; Dahmes, B; Levy, S L; Long, O; Lu, A; Mazur, M A; Richman, J D; Verkerke, W; Beck, T W; Beringer, J; Eisner, A M; Heusch, C A; Lockman, W S; Schalk, T; Schmitz, R E; Schumm, B A; Seiden, A; Spradlin, P; Turri, M; Walkowiak, W; Williams, D C; Wilson, M G; Albert, J; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Erwin, R J; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Ryd, A; Samuel, A; Yang, S; Jayatilleke, S; Mancinelli, G; Meadows, B T; Sokoloff, M D; Abe, T; Blanc, F; Bloom, P; Chen, S; Clark, P J; Ford, W T; Nauenberg, U; Olivas, A; Rankin, P; Roy, J; Smith, J G; van Hoek, W C; Zhang, L; Harton, J L; Hu, T; Soffer, A; Toki, W H; Wilson, R J; Zhang, J; Altenburg, D; Brandt, T; Brose, J; Colberg, T; Dickopp, M; Dubitzky, R S; Hauke, A; Lacker, H M; Maly, E; Müller-Pfefferkorn, R; Nogowski, R; Otto, S; Schubert, J; Schubert, K R; Schwierz, R; Spaan, B; Wilden, L; Bernard, D; Bonneaud, G R; Brochard, F; Cohen-Tanugi, J; Grenier, P; Thiebaux, Ch; Vasileiadis, G; Verderi, M; Khan, A; Lavin, D; Muheim, F; Playfer, S; Swain, J E; Andreotti, M; Azzolini, V; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Piemontese, L; Sarti, A; Treadwell, E; Baldini-Ferroli, R; Calcaterra, A; de Sangro, R; Falciai, D; Finocchiaro, G; Patteri, P; Piccolo, M; Zallo, A; Buzzo, A; Capra, R; Contri, R; Crosetti, G; Lo Vetere, M; Macri, M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Bailey, S; Morii, M; Won, E; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Eschrich, I; Gaillard, J R; Morton, G W; Nash, J A; Taylor, G P; Grenier, G J; Lee, S-J; Mallik, U; Cochran, J; Crawley, H B; Lamsa, J; Meyer, W T; Prell, S; Rosenberg, E I; Yi, J; Davier, M; Grosdidier, G; Höcker, A; Laplace, S; Diberder, F Le; Lepeltier, V; Lutz, A M; Petersen, T C; Plaszczynski, S; Schune, M H; Tantot, L; Wormser, G; Brigljević, V; Cheng, C H; Lange, D J; Simani, M C; Wright, D M; Bevan, A J; Coleman, J P; Fry, J R; Gabathuler, E; Gamet, R; Kay, M; Parry, R J; Payne, D J; Sloane, R J; Touramanis, C; Back, J J; Harrison, P F; Shorthouse, H W; Vidal, P B; Brown, C L; Cowan, G; Flack, R L; Flaecher, H U; George, S; Green, M G; Kurup, A; Marker, C E; McMahon, T R; Ricciardi, S; Salvatore, F; Vaitsas, G; Winter, M A; Brown, D; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Hart, P A; Hodgkinson, M C; Jackson, F; Lafferty, G D; Lyon, A J; Weatherall, J H; Williams, J C; Farbin, A; Jawahery, A; Kovalskyi, D; Lae, C K; Lillard, V; Roberts, D A; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Koptchev, V B; Moore, T B; Saremi, S; Staengle, H; Willocq, S; Cowan, R; Sciolla, G; Taylor, F; Yamamoto, R K; Mangeol, D J J; Patel, P M; Robertson, S H; Lazzaro, A; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Reidy, J; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Cote-Ahern, D; Taras, P; Nicholson, H; Cartaro, C; Cavallo, N; De Nardo, G; Fabozzi, F; Gatto, C; Lista, L; Paolucci, P; Piccolo, D; Sciacca, C; Baak, M A; Raven, G; LoSecco, J M; Gabriel, T A; Brau, B; Gan, K K; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pulliam, T; Wong, Q K; Brau, J; Frey, R; Igonkina, O; Potter, C T; Sinev, N B; Strom, D; Torrence, E; Colecchia, F; Dorigo, A; Galeazzi, F; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Tiozzo, G; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; de la Vaissière, Ch; Del Buono, L; Hamon, O; John, M J J; Leruste, Ph; Ocariz, J; Pivk, M; Roos, L; Stark, J; T'Jampens, S; Therin, G; Manfredi, P F; Re, V; Behera, P K; Gladney, L; Guo, Q H; Panetta, J; Anulli, F; Biasini, M; Peruzzi, I M; Pioppi, M; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Bucci, F; Calderini, G; Carpinelli, M; Del Gamba, V; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Martinez-Vidal, F; Morganti, M; Neri, N; Paoloni, E; Rama, M; Rizzo, G; Sandrelli, F; Walsh, J; Haire, M; Judd, D; Paick, K; Wagoner, D E; Danielson, N; Elmer, P; Lu, C; Miftakov, V; Olsen, J; Smith, A J S; Tanaka, H A; Varnes, E W; Bellini, F; Cavoto, G; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Mazzoni, M A; Morganti, S; Pierini, M; Piredda, G; SafaiTehrani, F; Voena, C; Christ, S; Wagner, G; Waldi, R; Adye, T; De Groot, N; Franek, B; Geddes, N I; Gopal, G P; Olaiya, E O; Xella, S M; Aleksan, R; Emery, S; Gaidot, A; Ganzhur, S F; Giraud, P-F; Hamel de Monchenault, G; Kozanecki, W; Langer, M; Legendre, M; London, G W; Mayer, B; Schott, G; Vasseur, G; Yeche, Ch; Zito, M; Purohit, M V; Weidemann, A W; Yumiceva, F X; Aston, D; Bartoldus, R; Berger, N; Boyarski, A M; Buchmueller, O L; Convery, M R; Cristinziani, M; Dong, D; Dorfan, J; Dujmic, D; Dunwoodie, W; Elsen, E E; Field, R C; Glanzman, T; Gowdy, S J; Grauges-Pous, E; Hadig, T; Halyo, V; Hryn'ova, T; Innes, W R; Jessop, C P; Kelsey, M H; Kim, P; Kocian, M L; Langenegger, U; Leith, D W G S; Libby, J; Luitz, S; Luth, V; Lynch, H L; Marsiske, H; Messner, R; Muller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Petrak, S; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Simi, G; Snyder, A; Soha, A; Stelzer, J; Su, D; Sullivan, M K; Va'vra, J; Wagner, S R; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wright, D H; Young, C C; Burchat, P R; Edwards, A J; Meyer, T I; Petersen, B A; Roat, C; Ahmed, M; Ahmed, S; Alam, M S; Ernst, J A; Saeed, M A; Saleem, M; Wappler, F R; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Kim, H; Ritchie, J L; Schwitters, R F; Izen, J M; Kitayama, I; Lou, X C; Ye, S; Bianchi, F; Bona, M; Gallo, F; Gamba, D; Borean, C; Bosisio, L; Della Ricca, G; Dittongo, S; Grancagnolo, S; Lanceri, L; Poropat, P; Vitale, L; Vuagnin, G; Panvini, R S; Banerjee, Sw; Brown, C M; Fortin, D; Jackson, P D; Kowalewski, R; Roney, J M; Band, H R; Dasu, S; Datta, M; Eichenbaum, A M; Johnson, J R; Kutter, P E; Li, H; Liu, R; Di Lodovico, F; Mihalyi, A; Mohapatra, A K; Pan, Y; Prepost, R; Sekula, S J; von Wimmersperg-Toeller, J H; Wu, J; Wu, S L; Yu, Z; Neal, H

2004-06-25

We present a measurement of time-dependent CP-violating asymmetries in decays of neutral B mesons to the final states D(*-/+)pi(+/-), using approximately 82x10(6) BBmacr; events recorded by the BABAR experiment at the PEP-II e(+)e(-) storage ring. Events containing these decays are selected with a partial reconstruction technique, in which only the high-momentum pi(+/-) from the B decay and the low-momentum pi(-/+) from the D(*-/+) decay are used. We measure the amplitude of the asymmetry to be -0.063+/-0.024(stat)+/-0.014(syst) and compute bounds on |sin((2beta+gamma)|.

Electromagnetic Meson Production in the Nucleon Resonance Region

DOE Office of Scientific and Technical Information (OSTI.GOV)

Volker Burkert; T.-S. H. Lee

Recent experimental and theoretical advances in investigating electromagnetic meson production reactions in the nucleon resonance region are reviewed. The article gives a description of current experimental facilities with electron and photon beams and presents a unified derivation of most of the phenomenological approaches being used to extract the resonance parameters from the data. The analyses of {pi} and {eta} production data and the resulting transition form factors for the {Delta}(1232)P{sub 33}, N(1535)S{sub 11}, N(1440)P{sub 11}, and N(1520)D{sub 13} resonances are discussed in detail. The status of our understanding of the reactions with production of two pions, kaons, and vector mesonsmore » is also reviewed.« less

In-medium properties of mesons

NASA Astrophysics Data System (ADS)

Metag, Volker; Nanova, Mariana; Brinkmann, Kai-Thomas

2017-01-01

In the project B.4, the modification of meson properties (mass, width) in a nuclear medium has been studied in photoproduction of mesons off nuclear targets. This work has been motivated by theoretical expectations of in-medium modifications of hadrons based on the conjecture of a partial restoration of chiral symmetry in a strongly interacting medium. It has been shown that these in-medium changes can be discussed in a compact form in terms of an optical potential describing the meson-nucleus interaction. Experimental approaches to determine the real and imaginary part of the meson-nucleus potential have been developed. The experiments have been performed with the Crystal Barrel/TAPS detector at the electron accelerator ELSA (Bonn) and the Crystal Ball/TAPS detector at MAMI (Mainz). Measuring the excitation function and momentum distribution for photo production of ω and η' mesons, the real parts of the ω and η'-nucleus potential, given by the in-medium mass shift, have been determined. For the η' meson a lowering of the mass at normal nuclear matter density by -(39±7(stat)±15(syst)) MeV is observed, while for the ω meson a slightly smaller mass shift is found, however, with much larger uncertainties, not excluding a zero mass shift. The imaginary part of the potentials has been extracted from the measurement of the transparency ratio which compares the meson production cross section per nucleon within a nucleus to the production cross section off the free proton. For the η' meson the imaginary part of the potential is found to be smaller than the real part. In case of the ω meson the opposite is observed. This makes the η' meson a good candidate for the search for meson-nucleus bound states while no resolved ω mesic states can be expected. The results are compared with theoretical predictions. An outlook on future experiments is given.

$$\\pi^0$$ Production with $K^-$ and $$\\pi^+$$ Beams at 530 GeV/c

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lanaro, Armando

1990-01-01

In thia theaia we report on measurements of inclusive neutral pion production at large transverse momenta (more » $$P_T$$) in collision of 530 GeV/c ($$\\sqrt{s}$$ = 31.5 GeV) $K^-$ and $$\\pi^+$$ beams with a copper and beryllium combined target. The $$\\pi^0$$ acceptance in center-of-mass rapidity is $$\\mid y \\mid$$ < 0.7, for $$P_T$$ values greater than 3.5 GeV/c (negative beam) and 4.25 GeV/c (positive beam). The data were taken using the large acceptance liquid argon calorimeter of the E706 spectrometer at Fermilab, and analyzed using the standard E706 reconstruction package. Ratios on $$\\pi^0$$ yields using $$\\pi^+, \\pi^-, K^-$$ and $p$ are presented. The results are used to examine issues of scaling in point-like hadronic collisions at high energies and large transverse momenta.« less

Measurement of sigma(Lambda(b)0) / sigma(anti-B 0) x B(Lambda0(b) ---> Lambda+(c) pi-) / B(anti-B0 ---> D+ pi-) in p anti-p collisions at S**(1/2) = 1.96-TeV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abulencia, A.; Acosta, D.; Adelman, Jahred A.

2006-01-01

The authors present the first observation of the baryon decay {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +} {pi}{sup -} followed by {Lambda}{sub c}{sup +} {yields} pK{sup -} {pi}{sup +} in 106 pb{sup -1} p{bar p} collisions at {radical}s = 1.96 TeV in the CDF experiment. IN order to reduce systematic error, the measured rate for {Lambda}{sub b}{sup 0} decay is normalized to the kinematically similar meson decay {bar B}{sup 0} {yields} D{sup +}{pi}{sup -} followed by D{sup +} {yields} {pi}{sup +}K{sup -}{pi}{sup +}. They report the ratio of production cross sections ({sigma}) times the ratio of branching fractions ({Beta}) formore » the momentum region integrated above p{sub T} > 6 GeV/c and pseudorapidity range |{eta}| < 1.3: {sigma}(p{bar p} {yields} {Lambda}{sub b}{sup 0}X)/{sigma}(p{bar p} {yields} {bar B}{sup 0} X) x {Beta}({Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +}{pi}{sup -})/{Beta}({bar B}{sup 0} {yields} D{sup +}{pi}{sup -}) = 0.82 {+-} 0.08(stat) {+-} 0.11(syst) {+-} 0.22 ({Beta}({Lambda}{sub c}{sup +} {yields} pK{sup -} {pi}{sup +})).« less

High-precision determination of the pi, K, D, and Ds decay constants from lattice QCD.

PubMed

Follana, E; Davies, C T H; Lepage, G P; Shigemitsu, J

2008-02-15

We determine D and D(s) decay constants from lattice QCD with 2% errors, 4 times better than experiment and previous theory: f(D(s))=241(3) MeV, f(D)=207(4) MeV, and fD(s))/f(D)=1.164(11). We also obtain f(K)/f(pi)=1.189(7) and (f(D(s))/f(D))/(f(K)/f(pi))=0.979(11). Combining with experiment gives V(us)=0.2262(14) and V(cs)/V(cd) of 4.43(41). We use a highly improved quark discretization on MILC gluon fields that include realistic sea quarks, fixing the u/d, s, and c masses from the pi, K, and eta(c) meson masses. This allows a stringent test against experiment for D and D(s) masses for the first time (to within 7 MeV).

Measurement of the ratios of branching fractions B(B0s --> Ds- pi+ pi+ pi-)/B(B0-->D- pi+ pi+ pi-) and B(B0s --> Ds- pi+)/B(B0-->D- pi+).

PubMed

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Chang, S H; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Chlebana, F; Cho, I; Cho, K; Chokheli, D; Chou, J P; Choudalakis, G; Chuang, S H; Chung, K; Chung, W H; Chung, Y S; Ciljak, M; Ciobanu, C I; Ciocci, M A; Clark, A; Clark, D; Coca, M; Compostella, G; Convery, M E; Conway, J; Cooper, B; Copic, K; Cordelli, M; Cortiana, G; Crescioli, F; Cuenca Almenar, C; Cuevas, J; Culbertson, R; Cully, J C; Cyr, D; DaRonco, S; D'Auria, S; Davies, T; D'Onofrio, M; Dagenhart, D; de Barbaro, P; De Cecco, S; Deisher, A; De Lentdecker, G; Dell'Orso, M; Delli Paoli, F; Demortier, L; Deng, J; Deninno, M; De Pedis, D; Derwent, P F; Di Giovanni, G P; Dionisi, C; Di Ruzza, B; Dittmann, J R; Dituro, P; Dörr, C; Donati, S; Donega, M; Dong, P; Donini, J; Dorigo, T; Dube, S; Efron, J; Erbacher, R; Errede, D; Errede, S; Eusebi, R; Fang, H C; Farrington, S; Fedorko, I; Fedorko, W T; Feild, R G; Feindt, M; Fernandez, J P; Field, R; Flanagan, G; Foland, A; Forrester, S; Foster, G W; Franklin, M; Freeman, J C; 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James, E; Jang, D; Jayatilaka, B; Jeans, D; Jensen, H; Jeon, E J; Jindariani, S; Jones, M; Joo, K K; Jun, S Y; Jung, J E; Junk, T R; Kamon, T; Karchin, P E; Kato, Y; Kemp, Y; Kephart, R; Kerzel, U; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kimura, N; Kirsch, L; Klimenko, S; Klute, M; Knuteson, B; Ko, B R; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kovalev, A; Kraan, A C; Kraus, J; Kravchenko, I; Kreps, M; Kroll, J; Krumnack, N; Kruse, M; Krutelyov, V; Kubo, T; Kuhlmann, S E; Kuhr, T; Kusakabe, Y; Kwang, S; Laasanen, A T; Lai, S; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; LeCompte, T; Lee, J; Lee, J; Lee, Y J; Lee, S W; Lefèvre, R; Leonardo, N; Leone, S; Levy, S; Lewis, J D; Lin, C; Lin, C S; Lindgren, M; Lipeles, E; Lister, A; Litvintsev, D O; Liu, T; Lockyer, N S; Loginov, A; Loreti, M; Loverre, P; Lu, R-S; Lucchesi, D; Lujan, P; Lukens, P; Lungu, G; Lyons, L; Lys, J; Lysak, R; Lytken, E; Mack, P; MacQueen, D; Madrak, R; Maeshima, K; Makhoul, K; Maki, T; Maksimovic, P; Malde, S; Manca, G; Margaroli, F; Marginean, R; Marino, C; Marino, C P; Martin, A; Martin, M; Martin, V; Martínez, M; Maruyama, T; Mastrandrea, P; Masubuchi, T; Matsunaga, H; Mattson, M E; Mazini, R; Mazzanti, P; McFarland, K S; McIntyre, P; McNulty, R; Mehta, A; Mehtala, P; Menzemer, S; Menzione, A; Merkel, P; Mesropian, C; Messina, A; Miao, T; Miladinovic, N; Miles, J; Miller, R; Mills, C; Milnik, M; Mitra, A; Mitselmakher, G; Miyamoto, A; Moed, S; Moggi, N; Mohr, B; Moore, R; Morello, M; Movilla Fernandez, P; Mülmenstädt, J; Mukherjee, A; Muller, Th; Mumford, R; Murat, P; Nachtman, J; Nagano, A; Naganoma, J; Nakano, I; Napier, A; Necula, V; Neu, C; Neubauer, M S; Nielsen, J; Nigmanov, T; Nodulman, L; Norniella, O; Nurse, E; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Oldeman, R; Orava, R; Osterberg, K; Pagliarone, C; Palencia, E; Papadimitriou, V; Paramonov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Pellett, D E; Penzo, A; Phillips, T J; Piacentino, G; Piedra, J; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Portell, X; Poukhov, O; Pounder, N; Prakoshyn, F; Pronko, A; Proudfoot, J; Ptohos, F; Punzi, G; Pursley, J; Rademacker, J; Rahaman, A; Ranjan, N; Rappoccio, S; Reisert, B; Rekovic, V; Renton, P; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robson, A; Rodrigo, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Ruiz, A; Russ, J; Rusu, V; Saarikko, H; Sabik, S; Safonov, A; Sakumoto, W K; Salamanna, G; Saltó, O; Saltzberg, D; Sánchez, C; Santi, L; Sarkar, S; Sartori, L; Sato, K; Savard, P; Savoy-Navarro, A; Scheidle, T; Schlabach, P; Schmidt, E E; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scott, A L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sfyrla, A; Shapiro, M D; Shears, T; Shepard, P F; Sherman, D; Shimojima, M; Shochet, M; Shon, Y; Shreyber, I; Sidoti, A; Sinervo, P; Sisakyan, A; Sjolin, J; Slaughter, A J; Slaunwhite, J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Soderberg, M; Soha, A; Somalwar, S; Sorin, V; Spalding, J; Spinella, F; Spreitzer, T; Squillacioti, P; Stanitzki, M; Staveris-Polykalas, A; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Stuart, D; Suh, J S; Sukhanov, A; Sun, H; Suzuki, T; Taffard, A; Takashima, R; Takeuchi, Y; Takikawa, K; Tanaka, M; Tanaka, R; Tecchio, M; Teng, P K; Terashi, K; Thom, J; Thompson, A S; Thomson, E; Tipton, P; Tiwari, V; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Tourneur, S; Trischuk, W; Tsuchiya, R; Tsuno, S; Turini, N; Ukegawa, F; Unverhau, T; Uozumi, S; Usynin, D; Vallecorsa, S; van Remortel, N; Varganov, A; Vataga, E; Vázquez, F; Velev, G; Veramendi, G; Veszpremi, V; Vidal, R; Vila, I; Vilar, R; Vine, T; Vollrath, I; Volobouev, I; Volpi, G; Würthwein, F; Wagner, P; Wagner, R G; Wagner, R L; Wagner, J; Wagner, W; Wallny, R; Wang, S M; Warburton, A; Waschke, S; Waters, D; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Wynne, S M; Yagil, A; Yamamoto, K; Yamaoka, J; Yamashita, T; Yang, C; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zaw, I; Zhang, X; Zhou, J; Zucchelli, S

2007-02-09

Using 355 pb;{-1} of data collected by the CDF II detector in pp[over ] collisions at sqrt[s]=1.96 TeV at the Fermilab Tevatron, we study the fully reconstructed hadronic decays B_{(s)};{0}-->D_{(s)};{-}pi;{+} and B_{(s)};{0}-->D_{(s)};{-}pi;{+}pi;{+}pi;{-}. We present the first measurement of the ratio of branching fractions B(B_{s};{0}-->D_{s};{-}pi;{+}pi;{+}pi;{-})/B(B;{0}-->D;{-}pi;{+}pi;{+}pi;{-})=1.05+/-0.10(stat)+/-0.22(syst). We also update our measurement of B(B_{s};{0}-->D_{s};{-}pi;{+})/B(B;{0}-->D;{-}pi;{+}) to 1.13+/-0.08(stat)+/-0.23(syst), improving the statistical uncertainty by more than a factor of 2. We find B(B_{s};{0}-->D_{s};{-}pi;{+})=[3.8+/-0.3(stat)+/-1.3(syst)]x10;{-3} and B(B_{s};{0}-->D_{s};{-}pi;{+}pi;{+}pi;{-})=[8.4+/-0.8(stat)+/-3.2(syst)]x10;{-3}.

Measurement of inclusive muon pair production by 225-GeV/c. pi. /sup +/,. pi. /sup -/, and proton beams with a large acceptance spectrometers. [Cross sections, 225 GeV/c, tables

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brason, J G

1977-05-01

Inclusive muon pair production by 225 GeV/c ..pi../sup +/, ..pi../sup -/ and proton beams incident upon carbon and tin targets was measured over a large range of kinematic variables (2m/sub ..mu../ < m/sub ..mu mu.. < 1 GeV/c/sup 2/, 0 < x/sub F/ < 1, P/sub perpendicular to/ < 4 GeV/c and vertical bar cos theta* vertical bar < .3). The value of the invariant cross section E d/sup 4/sigma/dmdx/sub f/dp/sup 2//sub perpendicular to/ is presented as a function of these variables. The vector mesons rho, ..omega.., phi, J and psi' appear in the data along with apparently nonresonant ..mu..-pairs.more » By looking for additional muons accompanying J ..-->.. ..mu../sup +/..mu../sup -/ events, a 1.0% upper limit on production of pairs of charmed particles in association with the J is obtained. Aspects of the continuum muon pair data are compared to Drell-Yan model calculations. The ratio of ..mu..-pairs produced by ..pi../sup +/ beam particles to ..mu..-pairs produced by ..pi../sup -/ beam particles supports electromagnetic production at high mass.« less

A Review: Some biological effects of high LET radiations

NASA Technical Reports Server (NTRS)

Wiley, A., Jr.

1972-01-01

There are qualitative and quantitative differences in the biological damage observed after exposure to high LET radiation as compared to that caused by low LET radiations. This review is concerned with these differences, which are ultimately reflected at the biochemical, cellular and even whole animal levels. In general, high LET radiations seem to produce biochemical damage which is more severe and possibly less repairable. Experimental data for those effects are presented in terms of biochemical RBE's with consideration of both early and late manifestations. An LET independent process by which significant biochemical damage may result from protons, neutrons and negative pion mesons is discussed.

Production of $${\\pi ^0}$$ and $$\\eta $$ mesons up to high transverse momentum in pp collisions at 2.76 TeV

DOE PAGES

Acharya, S.; Adamová, D.; Aggarwal, M. M.; ...

2017-05-22

The invariant differential cross sections for inclusive π 0 and η mesons at midrapidity were measured in pp collisions at √s=2.76 TeV for transverse momenta 0.4 < p T < 40 GeV/c and 0.6 < p T < 20 GeV/c, respectively, using the ALICE detector. This large range in p T was achieved by combining various analysis techniques and different triggers involving the electromagnetic calorimeter (EMCal). Particularly, a new single-cluster, shower-shape based method was developed for the identification of high-p T neutral pions, which exploits that the showers originating from their decay photons overlap in the EMCal. Above 4 GeV/c, the measured crossmore » sections are found to exhibit a similar power-law behavior with an exponent of about 6.3. Next-to-leading-order perturbative QCD calculations differ from the measured cross sections by about 30% for the π 0 , and between 30–50% for the η meson, while generator-level simulations with PYTHIA 8.2 describe the data to better than 10–30%, except at p T < 1 GeV/c. The new data can therefore be used to further improve the theoretical description of π 0 and η meson production.« less

Transverse-Target-Spin Asymmetry in Exclusive {omega}-Meson Electroproduction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Airapetian, A.; Akopov, N.; Akopov, Z.

Hard exclusive electroproduction of omega mesons is studied with the HERMES spectrometer at the DESY laboratory by scattering 27.6 GeV positron and electron beams off a transversely polarized hydrogen target. The amplitudes of five azimuthal modulations of the single-spin asymmetry of the cross section with respect to the transverse proton polarization are measured. They are determined in the entire kinematic region as well as for two bins in photon virtuality and momentum transfer to the nucleon. Also, a separation of asymmetry amplitudes into longitudinal and transverse components is done. These results are compared to a phenomenological model that includes themore » pion pole contribution. Within this model, the data favor a positive pi omega transition form factor.« less

Observation of {chi}{sub cJ} Radiative Decays to Light Vector Mesons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bennett, J. V.; Mitchell, R. E.; Shepherd, M. R.

2008-10-10

Using a total of 2.74x10{sup 7} decays of the {psi}(2S) collected with the CLEO-c detector, we present a study of {chi}{sub cJ}{yields}{gamma}V, where V={rho}{sup 0}, {omega}, {phi}. The transitions {chi}{sub c1}{yields}{gamma}{rho}{sup 0} and {chi}{sub c1}{yields}{gamma}{omega} are observed with B({chi}{sub c1}{yields}{gamma}{rho}{sup 0})=(2.43{+-}0.19{+-}0.22)x10{sup -4} and B({chi}{sub c1}{yields}{gamma}{omega})=(8.3{+-}1.5{+-}1.2)x10{sup -5}. In the {chi}{sub c1}{yields}{gamma}{rho}{sup 0} transition, the final state meson is dominantly longitudinally polarized. Upper limits on the branching fractions of other {chi}{sub cJ} states to light vector mesons are presented.

Observation of psi(3770) --> pi pi J/psi and measurement of Gamma ee[psi(2S)].

PubMed

Adam, N E; Alexander, J P; Berkelman, K; Cassel, D G; Crede, V; Duboscq, J E; Ecklund, K M; Ehrlich, R; Fields, L; Galik, R S; Gibbons, L; Gittelman, B; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Meyer, T O; Onyisi, P U E; Patterson, J R; Peterson, D; Phillips, E A; Pivarski, J; Riley, D; Ryd, A; Sadoff, A J; Schwarthoff, H; Shi, X; Shepherd, M R; Stroiney, S; Sun, W M; Urner, D; Wilksen, T; Weaver, K M; Weinberger, M; Athar, S B; Avery, P; Breva-Newell, L; Patel, R; Potlia, V; Stoeck, H; Yelton, J; Rubin, P; Cawlfield, C; Eisenstein, B I; Gollin, G D; Karliner, I; Kim, D; Lowrey, N; Naik, P; Sedlack, C; Selen, M; White, E J; Williams, J; Wiss, J; Asner, D M; Edwards, K W; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Gong, D T; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Li, S Z; Poling, R; Scott, A W; Smith, A; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A; Zweber, P; Ernst, J; Severini, H; Dytman, S A; Love, W; Mehrabyan, S; Mueller, J A; Savinov, V; Li, Z; Lopez, A; Mendez, H; Ramirez, J; Huang, G S; Miller, D H; Pavlunin, V; Sanghi, B; Shipsey, I P J; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Napolitano, J; He, Q; Muramatsu, H; Park, C S; Thorndike, E H; Coan, T E; Gao, Y S; Liu, F; Artuso, M; Boulahouache, C; Blusk, S; Butt, J; Dorjkhaidav, O; Li, J; Menaa, N; Mountain, R; Nandakumar, R; Randrianarivony, K; Redjimi, R; Sia, R; Skwarnicki, T; Stone, S; Wang, J C; Zhang, K; Csorna, S E; Bonvicini, G; Cinabro, D; Dubrovin, M; Briere, R A; Chen, G P; Chen, J; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L

2006-03-03

We observe signals for the decays psi(3770) --> XJ/psi from data acquired with the CLEO detector operating at the CESR e+ e- collider with square root of s = 3773 MeV. We measure the following branching fractions Beta(psi(3770) --> XJ/psi and significances: (189 +/- 20 +/- 20) x 10(-5) (11.6sigma) for X = pi+ pi-, (80 +/- 25 +/- 16) x 10(-5) (3.4sigma) for X = pi0 pi0, and (87 +/- 33 +/- 22) x 10(-5) (3.5sigma) for X = eta, where the errors are statistical and systematic, respectively. The radiative return process e+ e- --> gamma psi(2S) populates the same event sample and is used to measure Gamma ee[psi(2S)] = (2.54 +/- 0.03 +/- 0.11) keV.

Observation of {eta}{sup '} Decays to {pi}{sup +}{pi}{sup -}{pi}{sup 0} and {pi}{sup +}{pi}{sup -}e{sup +}e{sup -}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Naik, P.; Rademacker, J.; Asner, D. M.

Using {psi}(2S){yields}{pi}{sup +}{pi}{sup -}J/{psi}, J/{psi}{yields}{gamma}{eta}{sup '} events acquired with the CLEO-c detector at the CESR e{sup +}e{sup -} collider, we make the first observations of the decays {eta}{sup '}{yields}{pi}{sup +}{pi}{sup -}{pi}{sup 0} and {eta}{sup '}{yields}{pi}{sup +}{pi}{sup -}e{sup +}e{sup -}, measuring absolute branching fractions (37{sub -9}{sup +11}{+-}4)x10{sup -4} and (25{sub -9}{sup +12}{+-}5)x10{sup -4}, respectively. For {eta}{sup '}{yields}{pi}{sup +}{pi}{sup -}{pi}{sup 0}, this result probes the mechanism of isospin violation and the roles of {pi}{sup 0}/{eta}/{eta}{sup '}-mixing and final state rescattering in strong decays. We also set upper limits on branching fractions for {eta}{sup '} decays to {pi}{sup +}{pi}{sup -}{mu}{sup +}{mu}{sup -}, 2({pi}{supmore » +}{pi}{sup -}), {pi}{sup +}{pi}{sup -}2{pi}{sup 0}, 2({pi}{sup +}{pi}{sup -}){pi}{sup 0}, 3({pi}{sup +}{pi}{sup -}), and invisible final states.« less

CHARGED HEAVY MESONS (in French)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Leprince-Ringuet, L.

1960-03-01

The general properties of heavy mesons and hyperons are reviewed, and the results obtained with cosmic-ray studies at the Pic du Midi are reported. The investigations made with accelerators in the study of mesons are then described. The basic problems posed by heavy mesons and hyperons are reviewed with emphasis on the isotopic spin, strangeness, and parity. (tr-auth)

Scalar resonances in a unitary {pi}{pi} S-wave model for D{sup +}{yields}{pi}{sup +}{pi}{sup -}{pi}{sup +}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boito, D. R.; Instituto de Fisica, Universidade de Sao Paulo, C.P. 66318, 05315-970, Sao Paulo, SP; Dedonder, J.-P.

We propose a model for D{sup +}{yields}{pi}{sup +}{pi}{sup -}{pi}{sup +} decays following experimental results which indicate that the two-pion interaction in the S wave is dominated by the scalar resonances f{sub 0}(600)/{sigma} and f{sub 0}(980). The weak decay amplitude for D{sup +}{yields}R{pi}{sup +}, where R is a resonance that subsequently decays into {pi}{sup +}{pi}{sup -}, is constructed in a factorization approach. In the S wave, we implement the strong decay R{yields}{pi}{sup +}{pi}{sup -} by means of a scalar form factor. This provides a unitary description of the pion-pion interaction in the entire kinematically allowed mass range m{sub {pi}}{sub {pi}}{sup 2}more » from threshold to about 3 GeV{sup 2}. In order to reproduce the experimental Dalitz plot for D{sup +}{yields}{pi}{sup +}{pi}{sup -}{pi}{sup +}, we include contributions beyond the S wave. For the P wave, dominated by the {rho}(770){sup 0}, we use a Breit-Wigner description. Higher waves are accounted for by using the usual isobar prescription for the f{sub 2}(1270) and {rho}(1450){sup 0}. The major achievement is a good reproduction of the experimental m{sub {pi}}{sub {pi}}{sup 2} distribution, and of the partial as well as the total D{sup +}{yields}{pi}{sup +}{pi}{sup -}{pi}{sup +} branching ratios. Our values are generally smaller than the experimental ones. We discuss this shortcoming and, as a by-product, we predict a value for the poorly known D{yields}{sigma} transition form factor at q{sup 2}=m{sub {pi}}{sup 2}.« less

Regarding the scalar mesons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Liu Yunhu; Shao Jianxin; Wang Xiaogang

Based on the main assumption that the D{sub sJ}(2860) belongs to the 2{sup 3}P{sub 0} qq multiplet, the masses of the scalar meson nonet are estimated in the framework of the relativistic independent quark model, Regge phenomenology, and meson-meson mixing. We suggest that the a{sub 0}(1005), K{sub 0}*(1062), f{sub 0}(1103), and f{sub 0}(564) constitute the ground scalar meson nonet; it is supposed that these states would likely correspond to the observed states a{sub 0}(980), {kappa}(900), f{sub 0}(980), and f{sub 0}(600)/{sigma}, respectively. Also a{sub 0}(1516), K{sub 0}*(1669), f{sub 0}(1788), and f{sub 0}(1284) constitute the first radial scalar meson nonet, it ismore » supposed that these states would likely correspond to the observed states a{sub 0}(1450), K{sub 0}*(1430), f{sub 0}(1710), and f{sub 0}(1370), respectively. The scalar state f{sub 0}(1500) may be a good candidate for the ground scalar glueball. The agreement between the present findings and those given by other different approaches is satisfactory.« less

Determination of the S-Wave Pi Pi Scattering Lengths From a Study of K - to Pi - Pi0 Pi0 Decays

DOE Office of Scientific and Technical Information (OSTI.GOV)

Batley, J.R.; Culling, A.J.; Kalmus, G.

We report the results from a study of the full sample of {approx}6.031 x 10{sup 7} K{sup {+-}} {yields} {pi}{sup {+-}}{pi}{sup 0}{pi}{sup 0} decays recorded by the NA48/2 experiment at the CERN SPS. As first observed in this experiment, the {pi}{sup 0}{pi}{sup 0} invariant mass (M{sub 00}) distribution shows a cusp-like anomaly in the region around M{sub 00} = 2m{sub +}, where m{sub +} is the charged pion mass. This anomaly has been interpreted as an effect due mainly to the final state charge exchange scattering process {pi}{sup +}{pi}{sup -} {yields} {pi}{sup 0}{pi}{sup 0} in K{sup {+-}} {yields} {pi}{sup {+-}}{pi}{supmore » +}{pi}{sup -} decay. Fits to the M{sub 00} distribution using two different theoretical formulations provide the presently most precise determination of a{sub 0} - a{sub 2}, the difference between the {pi}{pi} S-wave scattering lengths in the isospin I = 0 and I = 2 states. Higher-order {pi}{pi} rescattering terms, included in the two formulations, allow also an independent, though less precise, determination of a{sub 2}.« less

The Reactions Gamma + Proton ---> Positive Pion Negative Pion Positive Pion Negative Pion Proton and Gamma + Proton ---> KAON(+,-) PION(-,+) Neutral Kaon Proton at 20 GEV

NASA Astrophysics Data System (ADS)

McCrory, Elliott Simkins

The reactions (gamma)p (--->) (pi)('+)(pi)('-)(pi)('+)(pi)(' -)p and (gamma)p (--->) K('(+OR-))(pi)('(-OR+))K('0)p at 20 GeV are studied from data obtained during the BC72 experiment, run at the SLAC 1 meter Hybrid Bubble Chamber facility from 1980 to 1982. The 5702 events in the first channel represent a cross section of 2.54 (+OR-) 0.24 (mu)b; the 235 events in the second channel represent a cross section of 380 (+OR-) 40 nb. The primary radial excitation of the (rho)(770), commonly called the (rho)(1600), is observed in half of the 4(pi) channel, but with parameters markedly different from what has been previously published. Production of the resonance is peripheral, exponential t dependence of 7.5 (GeV)('-2), with s-channel helicity conserved at the 90% level. A variety of methods have been used to calculate the mass and the width of the (rho)' resonance, the strongest (and new for this channel) being a maximum likelihood fit to all aspects of the 4(pi) data. Forty percent of the 4(pi) channel is associated with (DELTA)('++)(1232) production. We have studied, in particular, (gamma)p (--->) A(,n)(DELTA)('++) and see predominantly production of the A(,2) tensor meson resonance with an admixture of the pseudoscalar A(,1) mean resonance. The KK(pi) channel is dominated by K*K production. The K*K system does not appear to be associated with resonance production.

Scalar resonances in a unitary {pi}{pi} S-wave model for D{sup +} {r_arrow} {pi}{sup+}{pi}{sup-}{pi}{sup+}.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Boito, D. R.; Dedonder, J.-P.; El-Bennich, B.

We propose a model for D{sup +} {yields} {pi}{sup +}{pi}{sup -}{pi}{sup +} decays following experimental results which indicate that the two-pion interaction in the S wave is dominated by the scalar resonances f{sub 0}(600)/{sigma} and f{sub 0}(980). The weak decay amplitude for D{sup +} {yields} R{pi}{sup +}, where R is a resonance that subsequently decays into {pi}{sup +}{pi}{sup -}, is constructed in a factorization approach. In the S wave, we implement the strong decay R {yields} {pi}{sup +}{pi}{sup -} by means of a scalar form factor. This provides a unitary description of the pion-pion interaction in the entire kinematically allowedmore » mass range m{sub {pi}{pi}}{sup 2} from threshold to about 3 GeV{sup 2}. In order to reproduce the experimental Dalitz plot for D{sup +} {yields} {pi}{sup +}{pi}{sup -}{pi}{sup +}, we include contributions beyond the S wave. For the P wave, dominated by the {rho}(770){sup 0}, we use a Breit-Wigner description. Higher waves are accounted for by using the usual isobar prescription for the f{sub 2}(1270) and {rho}(1450){sup 0}. The major achievement is a good reproduction of the experimental m{sub {pi}{pi}}{sup 2} distribution, and of the partial as well as the total D{sup +} {yields} {pi}{sup +}{pi}{sup -}{pi}{sup +} branching ratios. Our values are generally smaller than the experimental ones. We discuss this shortcoming and, as a by-product, we predict a value for the poorly known D {yields} {sigma} transition form factor at q{sup 2} = m{sub {pi}}{sup 2}.« less

Physics opportunities with meson beams

DOE PAGES

Briscoe, William J.; Doring, Michael; Haberzettl, Helmut; ...

2015-10-20

Over the past two decades, meson photo- and electro-production data of unprecedented quality and quantity have been measured at electromagnetic facilities worldwide. By contrast, the meson-beam data for the same hadronic final states are mostly outdated and largely of poor quality, or even nonexistent, and thus provide inadequate input to help interpret, analyze, and exploit the full potential of the new electromagnetic data. To reap the full benefit of the high-precision electromagnetic data, new high-statistics data from measurements with meson beams, with good angle and energy coverage for a wide range of reactions, are critically needed to advance our knowledgemore » in baryon and meson spectroscopy and other related areas of hadron physics. To address this situation, a state of-the-art meson-beam facility needs to be constructed. Furthermore, the present paper summarizes unresolved issues in hadron physics and outlines the vast opportunities and advances that only become possible with such a facility.« less

Physics opportunities with meson beams

NASA Astrophysics Data System (ADS)

Briscoe, William J.; Döring, Michael; Haberzettl, Helmut; Manley, D. Mark; Naruki, Megumi; Strakovsky, Igor I.; Swanson, Eric S.

2015-10-01

Over the past two decades, meson photo- and electroproduction data of unprecedented quality and quantity have been measured at electromagnetic facilities worldwide. By contrast, the meson-beam data for the same hadronic final states are mostly outdated and largely of poor quality, or even non-existent, and thus provide inadequate input to help interpret, analyze, and exploit the full potential of the new electromagnetic data. To reap the full benefit of the high-precision electromagnetic data, new high-statistics data from measurements with meson beams, with good angle and energy coverage for a wide range of reactions, are critically needed to advance our knowledge in baryon and meson spectroscopy and other related areas of hadron physics. To address this situation, a state-of-the-art meson-beam facility needs to be constructed. The present paper summarizes unresolved issues in hadron physics and outlines the vast opportunities and advances that only become possible with such a facility.

Negative radiation forces and the asymmetry of scattered radiation: spheres in Bessel beams

NASA Astrophysics Data System (ADS)

Marston, Philip L.; Zhang, Likun

2011-11-01

The discovery that acoustical and optical, radiation forces computed on spheres placed on the axis of acoustical and optical Bessel beams may be opposite the direction of beam propagation makes it appropriate to reexamine the relationship between radiation forces and the asymmetry of the scattered radiation. For all of the previously identified acoustical cases in which the force was negative and the scattering pattern was also computed, it was found that the backscattering was suppressed and the forward scattering relatively enhanced (see e.g.). In the present research the acoustic radiation force on an arbitrary isotropic sphere is related to the asymmetry in the scattering and the extinction introduced by the sphere for the case of a helical Bessel beam of arbitrary order. The analysis confirms that conditions are more favorable for generating negative forces when the asymmetry is such that the backscattering is suppressed relative to the forward scattering. It is also found, however, that absorption of power by the sphere gives rise to a positive force contribution, a term which has been neglected in the corresponding optical analysis.

An a 0 resonance in strongly coupled π η , K K ¯ scattering from lattice QCD

DOE PAGES

Dudek, Jozef J.; Edwards, Robert G.; Wilson, David J.

2016-05-11

Here, we present the first calculation of coupled-channel meson-meson scattering in the isospinmore » $=1$, $G$-parity negative sector, with channels $$\\pi \\eta$$, $$K\\overline{K}$$ and $$\\pi \\eta'$$, in a first-principles approach to QCD. From the discrete spectrum of eigenstates in three volumes extracted from lattice QCD correlation functions we determine the energy dependence of the $S$-matrix, and find that the $S$-wave features a prominent cusp-like structure in $$\\pi \\eta \\to \\pi \\eta$$ close to $$K\\overline{K}$$ threshold coupled with a rapid turn on of amplitudes leading to the $$K\\overline{K}$$ final-state. This behavior is traced to an $$a_0(980)$$-like resonance, strongly coupled to both $$\\pi \\eta$$ and $$K\\overline{K}$$, which is identified with a pole in the complex energy plane, appearing on only a single unphysical Riemann sheet. Consideration of $D$-wave scattering suggests a narrow tensor resonance at higher energy.« less

An a 0 resonance in strongly coupled π η , K K ¯ scattering from lattice QCD

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dudek, Jozef J.; Edwards, Robert G.; Wilson, David J.

Here, we present the first calculation of coupled-channel meson-meson scattering in the isospinmore » $=1$, $G$-parity negative sector, with channels $$\\pi \\eta$$, $$K\\overline{K}$$ and $$\\pi \\eta'$$, in a first-principles approach to QCD. From the discrete spectrum of eigenstates in three volumes extracted from lattice QCD correlation functions we determine the energy dependence of the $S$-matrix, and find that the $S$-wave features a prominent cusp-like structure in $$\\pi \\eta \\to \\pi \\eta$$ close to $$K\\overline{K}$$ threshold coupled with a rapid turn on of amplitudes leading to the $$K\\overline{K}$$ final-state. This behavior is traced to an $$a_0(980)$$-like resonance, strongly coupled to both $$\\pi \\eta$$ and $$K\\overline{K}$$, which is identified with a pole in the complex energy plane, appearing on only a single unphysical Riemann sheet. Consideration of $D$-wave scattering suggests a narrow tensor resonance at higher energy.« less

KLOE results on light meson spectroscopy and prospects for KLOE-2

NASA Astrophysics Data System (ADS)

Gauzzi, Paolo; KLOE-2 Collaboration

2012-03-01

The results obtained by the KLOE Collaboration on light meson spectroscopy are presented. The radiative decay phi → ηγ have been used to study several η decay channels. The Dalitz plot distributions of the η → 3π decays, both in charged and neutral final states have been measured. The box anomaly contribution in η → π+ π-γ has been investigated in, and the rare decays η → π0γγ, η → π+π-e+e- and η → e+e-e+e- have been measured. Also the strategy for the measurement of the transition form factor of phi → ηe+e- is described. The radiateve process phi → η'γ has been used to study the η' → ηππ decay channels, obtaining a measurement of the pseudoscalar mixing angle, and finding an evidence for a gluonium content of η'. The decays phi → PPγ where P means a pseudoscalar meson, have been exploited to investigate the light scalar mesons, f0(980), a0(980), and σ(600). The couplings of the scalar mesons to Kbar K, ππ or ππ0, and to the phi resonance have been measured. The prospects for the new KLOE-2 data-taking just started at the upgraded DAΦNE with an upgraded detector are described.

Model prediction for temperature dependence of meson pole masses from lattice QCD results on meson screening masses

NASA Astrophysics Data System (ADS)

Ishii, Masahiro; Kouno, Hiroaki; Yahiro, Masanobu

2017-06-01

We propose a practical effective model by introducing temperature (T ) dependence to the coupling strengths of four-quark and six-quark Kobayashi-Maskawa-'t Hooft interactions in the 2 +1 flavor Polyakov-loop extended Nambu-Jona-Lasinio model. The T dependence is determined from lattice QCD (LQCD) data on the renormalized chiral condensate around the pseudocritical temperature Tcχ of chiral crossover and the screening-mass difference between π and a0 mesons in T >1.1 Tcχ where only the U (1 )A-symmetry breaking survives. The model well reproduces LQCD data on screening masses Mξscr(T ) for both pseudoscalar mesons (ξ =π ,K ,η ,η' ) and scalar ones (ξ =a0,κ ,σ ,f0 ), particularly in T ≳Tcχ . Using this effective model, we predict meson pole masses Mξpole(T ) for scalar and pseudoscalar mesons. For η' meson, the prediction is consistent with the experimental value at finite T measured in heavy-ion collisions. We point out that the relation Mξscr(T )-Mξpole(T )≈Mξ' scr(T )-Mξ' pole(T ) is pretty good when ξ and ξ' are the scalar mesons, and show that the relation Mξscr(T )/Mξ' scr(T )≈Mξpole(T )/Mξ' pole(T ) is well satisfied within 20% error when ξ and ξ' are the pseudoscalar mesons and also when ξ and ξ' are the scalar mesons.

Climate Response to Negative Greenhouse Gas Radiative Forcing in Polar Winter

NASA Astrophysics Data System (ADS)

Flanner, M. G.; Huang, X.; Chen, X.; Krinner, G.

2018-02-01

Greenhouse gas (GHG) additions to Earth's atmosphere initially reduce global outgoing longwave radiation, thereby warming the planet. In select environments with temperature inversions, however, increased GHG concentrations can actually increase local outgoing longwave radiation. Negative top of atmosphere and effective radiative forcing (ERF) from this situation give the impression that local surface temperatures could cool in response to GHG increases. Here we consider an extreme scenario in which GHG concentrations are increased only within the warmest layers of winter near-surface inversions of the Arctic and Antarctic. We find, using a fully coupled Earth system model, that the underlying surface warms despite the GHG addition exerting negative ERF and cooling the troposphere in the vicinity of the GHG increase. This unique radiative forcing and thermal response is facilitated by the high stability of the polar winter atmosphere, which inhibit thermal mixing and amplify the impact of surface radiative forcing on surface temperature. These findings also suggest that strategies to exploit negative ERF via injections of short-lived GHGs into inversion layers would likely be unsuccessful in cooling the planetary surface.

Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941.

PubMed

Raynaud, Florence I; Eccles, Suzanne A; Patel, Sonal; Alix, Sonia; Box, Gary; Chuckowree, Irina; Folkes, Adrian; Gowan, Sharon; De Haven Brandon, Alexis; Di Stefano, Francesca; Hayes, Angela; Henley, Alan T; Lensun, Letitia; Pergl-Wilson, Giles; Robson, Anthony; Saghir, Nahid; Zhyvoloup, Alexander; McDonald, Edward; Sheldrake, Peter; Shuttleworth, Stephen; Valenti, Melanie; Wan, Nan Chi; Clarke, Paul A; Workman, Paul

2009-07-01

The phosphatidylinositide 3-kinase pathway is frequently deregulated in human cancers and inhibitors offer considerable therapeutic potential. We previously described the promising tricyclic pyridofuropyrimidine lead and chemical tool compound PI-103. We now report the properties of the pharmaceutically optimized bicyclic thienopyrimidine derivatives PI-540 and PI-620 and the resulting clinical development candidate GDC-0941. All four compounds inhibited phosphatidylinositide 3-kinase p110alpha with IC(50) < or = 10 nmol/L. Despite some differences in isoform selectivity, these agents exhibited similar in vitro antiproliferative properties to PI-103 in a panel of human cancer cell lines, with submicromolar potency in PTEN-negative U87MG human glioblastoma cells and comparable phosphatidylinositide 3-kinase pathway modulation. PI-540 and PI-620 exhibited improvements in solubility and metabolism with high tissue distribution in mice. Both compounds gave improved antitumor efficacy over PI-103, following i.p. dosing in U87MG glioblastoma tumor xenografts in athymic mice, with treated/control values of 34% (66% inhibition) and 27% (73% inhibition) for PI-540 (50 mg/kg b.i.d.) and PI-620 (25 mg/kg b.i.d.), respectively. GDC-0941 showed comparable in vitro antitumor activity to PI-103, PI-540, and PI-620 and exhibited 78% oral bioavailability in mice, with tumor exposure above 50% antiproliferative concentrations for >8 hours following 150 mg/kg p.o. and sustained phosphatidylinositide 3-kinase pathway inhibition. These properties led to excellent dose-dependent oral antitumor activity, with daily p.o. dosing at 150 mg/kg achieving 98% and 80% growth inhibition of U87MG glioblastoma and IGROV-1 ovarian cancer xenografts, respectively. Together, these data support the development of GDC-0941 as a potent, orally bioavailable inhibitor of phosphatidylinositide 3-kinase. GDC-0941 has recently entered phase I clinical trials.

Biological properties of potent inhibitors of class I phosphatidylinositide 3-kinases: from PI-103 through PI-540, PI-620 to the oral agent GDC-0941

PubMed Central

Raynaud, Florence I.; Eccles, Suzanne A.; Patel, Sonal; Alix, Sonia; Box, Gary; Chuckowree, Irina; Folkes, Adrian; Gowan, Sharon; De Haven Brandon, Alexis; Di Stefano, Francesca; Hayes, Angela; Henley, Alan T.; Lensun, Letitia; Pergl-Wilson, Giles; Robson, Anthony; Saghir, Nahid; Zhyvoloup, Alexander; McDonald, Edward; Sheldrake, Peter; Shuttleworth, Stephen; Valenti, Melanie; Wan, Nan Chi; Clarke, Paul A.; Workman, Paul

2009-01-01

The phosphatidylinositide 3-kinase pathway is frequently deregulated in human cancers and inhibitors offer considerable therapeutic potential. We previously described the promising tricyclic pyridofuropyrimidine lead and chemical tool compound PI-103. We now report the properties of the pharmaceutically optimized bicyclic thienopyrimidine derivatives PI-540 and PI-620 and the resulting clinical development candidate GDC-0941. All four compounds inhibited phosphatidylinositide 3-kinase p110α with IC50 ≤ 10 nmol/L. Despite some differences in isoform selectivity, these agents exhibited similar in vitro antiproliferative properties to PI-103 in a panel of human cancer cell lines, with submicromolar potency in PTEN-negative U87MG human glioblastoma cells and comparable phosphatidylinositide 3-kinase pathway modulation. PI-540 and PI-620 exhibited improvements in solubility and metabolism with high tissue distribution in mice. Both compounds gave improved antitumor efficacy over PI-103, following i.p. dosing in U87MG glioblastoma tumor xenografts in athymic mice, with treated/control values of 34% (66% inhibition) and 27% (73% inhibition) for PI-540 (50 mg/kg b.i.d.) and PI-620 (25 mg/kg b.i.d.), respectively. GDC-0941 showed comparable in vitro antitumor activity to PI-103, PI-540, and PI-620 and exhibited 78% oral bioavailability in mice, with tumor exposure above 50% anti-proliferative concentrations for >8 hours following 150 mg/kg p.o. and sustained phosphatidylinositide 3-kinase pathway inhibition. These properties led to excellent dose-dependent oral antitumor activity, with daily p.o. dosing at 150 mg/kg achieving 98% and 80% growth inhibition of U87MG glioblastoma and IGROV-1 ovarian cancer xenografts, respectively. Together, these data support the development of GDC-0941 as a potent, orally bioavailable inhibitor of phosphatidylinositide 3-kinase. GDC-0941 has recently entered phase I clinical trials. PMID:19584227

A Dependence of Charmed Meson Production (in Portuguese)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Alves, Gilvan Augusto

One report is presented of a recent direct measurement of the nucleon number (A) dependence of the production cross sections for the charmed mesonsmore » $D^0$ and $D^+$ using $$\\pi^+_{-}$$ and $$K^+_{-}$$ beams incident on a segmented target of Be, Al, Cu and W. The data derive from the experiment E769 - Hadroproductlon of Charm at Fermilab. The experimental apparatus is described together with the following analysis. Starting from a sample of -1500 D mesons in the range of $$O< x_{f} <1$$, the data are found to be well described by the parameterization $$\\sigma_{A}$$ = $$\\sigma_{O}$$ , with $$\\alpha = 0.99 \\pm 0.03$$. The $$x_f$$ dependence of $$\\alpha$$ is examined and the results obtained are compared with those of other .experiments and wl th -theoretical expectations based on perturbatlve QCD and on an EMC like model of nuclear shadowing« less

Measurements of branching fractions and CP-violating asymmetries in B meson decays to charmless two-body states containing a K(0).

PubMed

Aubert, B; Barate, R; Boutigny, D; Couderc, F; Gaillard, J-M; Hicheur, A; Karyotakis, Y; Lees, J P; Robbe, P; Tisserand, V; Zghiche, A; Palano, A; Pompili, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Day, C T; Gill, M S; Gritsan, A V; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kolomensky, Yu G; Kukartsev, G; LeClerc, C; Levi, M E; Lynch, G; Mir, L M; Oddone, P J; Orimoto, T J; Pripstein, M; Roe, N A; Romosan, A; Ronan, M T; Shelkov, V G; Telnov, A V; Wenzel, W A; Ford, K; Harrison, T J; Hawkes, C M; Knowles, D J; Morgan, S E; Penny, R C; Watson, A T; Watson, N K; Goetzen, K; Held, T; Koch, H; Lewandowski, B; Pelizaeus, M; Peters, K; Schmuecker, H; Steinke, M; Boyd, J T; Chevalier, N; Cottingham, W N; Kelly, M P; Latham, T E; Mackay, C; Wilson, F F; Abe, K; Cuhadar-Donszelmann, T; Hearty, C; Mattison, T S; McKenna, J A; Thiessen, D; Kyberd, P; McKemey, A K; Teodorescu, L; Blinov, V E; Bukin, A D; Golubev, V B; Ivanchenko, V N; Kravchenko, E A; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Yushkov, A N; Best, D; Bruinsma, M; Chao, M; Eschrich, I; Kirkby, D; Lankford, A J; Mandelkern, M; Mommsen, R K; Roethel, W; Stoker, D P; Buchanan, C; Hartfiel, B L; Gary, J W; Layter, J; Shen, B C; Wang, K; del Re, D; Hadavand, H K; Hill, E J; MacFarlane, D B; Paar, H P; Rahatlou, Sh; Sharma, V; Berryhill, J W; Campagnari, C; Dahmes, B; Levy, S L; Long, O; Lu, A; Mazur, M A; Richman, J D; Verkerke, W; Beck, T W; Beringer, J; Eisner, A M; Heusch, C A; Lockman, W S; Schalk, T; Schmitz, R E; Schumm, B A; Seiden, A; Spradlin, P; Turri, M; Walkowiak, W; Williams, D C; Wilson, M G; Albert, J; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Erwin, R J; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Ryd, A; Samuel, A; Yang, S; Jayatilleke, S; Mancinelli, G; Meadows, B T; Sokoloff, M D; Abe, T; Blanc, F; Bloom, P; Chen, S; Clark, P J; Ford, W T; Nauenberg, U; Olivas, A; Rankin, P; Roy, J; Smith, J G; van Hoek, W C; Zhang, L; Harton, J L; Hu, T; Soffer, A; Toki, W H; Wilson, R J; Zhang, J; Aleksan, R; Emery, S; Gaidot, A; Ganzhur, S F; Giraud, P-F; Hamelde Monchenault, G; Kozanecki, W; Langer, M; Legendre, M; London, G W; Mayer, B; Schott, G; Vasseur, G; Yeche, Ch; Zito, M; Altenburg, D; Brandt, T; Brose, J; Colberg, T; Dickopp, M; Hauke, A; Lacker, H M; Maly, E; Müller-Pfefferkorn, R; Nogowski, R; Otto, S; Schubert, J; Schubert, K R; Schwierz, R; Spaan, B; Wilden, L; Bernard, D; Bonneaud, G R; Brochard, F; Cohen-Tanugi, J; Grenier, P; Thiebaux, Ch; Vasileiadis, G; Verderi, M; Khan, A; Lavin, D; Muheim, F; Playfer, S; Swain, J E; Andreotti, M; Azzolini, V; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Piemontese, L; Sarti, A; Treadwell, E; Anulli, F; Baldini-Ferroli, R; Calcaterra, A; De Sangro, R; Falciai, D; Finocchiaro, G; Patteri, P; Peruzzi, I M; Piccolo, M; Zallo, A; Buzzo, A; Capra, R; Contri, R; Crosetti, G; Lo Vetere, M; Macri, M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Bailey, S; Morii, M; Won, E; Dubitzky, R S; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Gaillard, J R; Morton, G W; Nash, J A; Taylor, G P; Grenier, G J; Lee, S-J; Mallik, U; Cochran, J; Crawley, H B; Lamsa, J; Meyer, W T; Prell, S; Rosenberg, E I; Yi, J; Biasini, M; Pioppi, M; Davier, M; Grosdidier, G; Höcker, A; Laplace, S; Diberder, F Le; Lepeltier, V; Lutz, A M; Petersen, T C; Plaszczynski, S; Schune, M H; Tantot, L; Wormser, G; Brigljević, V; Cheng, C H; Lange, D J; Simani, M C; Wright, D M; Bevan, A J; Coleman, J P; Fry, J R; Gabathuler, E; Gamet, R; Kay, M; Parry, R J; Payne, D J; Sloane, R J; Touramanis, C; Back, J J; Cormack, C M; Harrison, P F; Shorthouse, H W; Vidal, P B; Brown, C L; Cowan, G; Flack, R L; Flaecher, H U; George, S; Green, M G; Kurup, A; Marker, C E; McMahon, T R; Ricciardi, S; Salvatore, F; Vaitsas, G; Winter, M A; Brown, D; Davis, C L; Allison, J; Barlow, N R; Barlow, R J; Hart, P A; Hodgkinson, M C; Jackson, F; Lafferty, G D; Lyon, A J; Weatherall, J H; Williams, J C; Farbin, A; Hulsbergen, W D; Jawahery, A; Kovalskyi, D; Lae, C K; Lillard, V; Roberts, D A; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Koptchev, V B; Moore, T B; Saremi, S; Staengle, H; Willocq, S; Cowan, R; Sciolla, G; Taylor, F; Yamamoto, R K; Mangeol, D J J; Patel, P M; Robertson, S H; Lazzaro, A; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Reidy, J; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Cote-Ahern, D; Taras, P; Nicholson, H; Raven, G; Cartaro, C; Cavallo, N; De Nardo, G; Fabozzi, F; Gatto, C; Lista, L; Paolucci, P; Piccolo, D; Sciacca, C; Jessop, C P; LoSecco, J M; Gabriel, T A; Brau, B; Gan, K K; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pulliam, T; Ter-Antonyan, R; Wong, Q K; Brau, J; Frey, R; Igonkina, O; Potter, C T; Sinev, N B; Strom, D; Torrence, E; Colecchia, F; Dorigo, A; Galeazzi, F; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Tiozzo, G; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; De la Vaissière, Ch; Del Buono, L; Hamon, O; John, M J J; Leruste, Ph; Ocariz, J; Pivk, M; Roos, L; Stark, J; T'Jampens, S; Therin, G; Manfredi, P F; Re, V; Behera, P K; Gladney, L; Guo, Q H; Panetta, J; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Bucci, F; Calderini, G; Carpinelli, M; Del Gamba, V; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Martinez-Vidal, F; Morganti, M; Neri, N; Paoloni, E; Rama, M; Rizzo, G; Sandrelli, F; Walsh, J; Haire, M; Judd, D; Paick, K; Wagoner, D E; Cavoto, G; Danielson, N; Elmer, P; Lu, C; Miftakov, V; Olsen, J; Smith, A J S; Bellini, F; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Mazzoni, M A; Morganti, S; Pierini, M; Piredda, G; Safai Tehrani, F; Voena, C; Christ, S; Wagner, G; Waldi, R; Adye, T; De Groot, N; Franek, B; Geddes, N I; Gopal, G P; Olaiya, E O; Xella, S M; Purohit, M V; Weidemann, A W; Yumiceva, F X; Aston, D; Bartoldus, R; Berger, N; Boyarski, A M; Buchmueller, O L; Convery, M R; Cristinziani, M; Dong, D; Dorfan, J; Dujmic, D; Dunwoodie, W; Elsen, E E; Field, R C; Glanzman, T; Gowdy, S J; Hadig, T; Halyo, V; Hryn'ova, T; Innes, W R; Kelsey, M H; Kim, P; Kocian, M L; Langenegger, U; Leith, D W G S; Libby, J; Luitz, S; Luth, V; Lynch, H L; Marsiske, H; Messner, R; Muller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Petrak, S; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Simi, G; Snyder, A; Soha, A; Stelzer, J; Su, D; Sullivan, M K; Va'vra, J; Wagner, S R; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wright, D H; Young, C C; Burchat, P R; Edwards, A J; Meyer, T I; Petersen, B A; Roat, C; Ahmed, M; Ahmed, S; Alam, M S; Ernst, J A; Saeed, M A; Saleem, M; Wappler, F R; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Kim, H; Ritchie, J L; Satpathy, A; Schwitters, R F; Izen, J M; Kitayama, I; Lou, X C; Ye, S; Bianchi, F; Bona, M; Gallo, F; Gamba, D; Borean, C; Bosisio, L; Della Ricca, G; Dittongo, S; Grancagnolo, S; Lanceri, L; Poropat, P; Vitale, L; Vuagnin, G; Panvini, R S; Banerjee, Sw; Brown, C M; Fortin, D; Jackson, P D; Kowalewski, R; Roney, J M; Band, H R; Dasu, S; Datta, M; Eichenbaum, A M; Johnson, J R; Kutter, P E; Li, H; Liu, R; Lodovico, F Di; Mihalyi, A; Mohapatra, A K; Pan, Y; Prepost, R; Sekula, S J; von Wimmersperg-Toeller, J H; Wu, J; Wu, S L; Yu, Z; Neal, H

2004-05-21

We present measurements of branching fractions and CP-violating asymmetries in decays of B mesons to two-body final states containing a K0. The results are based on a data sample of approximately 88 x 10(6) Upsilon(4S)-->BB decays collected with the BABAR detector at the PEP-II asymmetric-energy B Factory at SLAC. We measure B(B+-->K(0)pi(+))=(22.3+/-1.7+/-1.1)x10(-6), B(B0-->K(0)pi(0)=(11.4+/-1.7+/-0.8)x10(-6), B(B+-->K(0)K+)<2.5 x 10(-6), and B(B0-->K(0)K(0)<1.8 x 10(-6), where the first uncertainty is statistical and the second is systematic, and the upper limits are at the 90% confidence level. In addition, the following CP-violating asymmetries have been measured: A(CP)(B+-->K(0)pi(+))=-0.05+/-0.08+/-0.01 and A(CP)(B0-->K(0)pi(0)=0.03+/-0.36+/-0.11.

Measurements of the branching fractions for B{sub (s)}{yields}D{sub (s)}{pi}{pi}{pi} and {Lambda}{sub b}{sup 0}{yields}{Lambda}{sub c}{sup +}{pi}{pi}{pi}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aaij, R.; Bauer, Th.; Beuzekom, M. van

Branching fractions of the decays H{sub b}{yields}H{sub c}{pi}{sup -}{pi}{sup +}{pi}{sup -} relative to H{sub b}{yields}H{sub c}{pi}{sup -} are presented, where H{sub b} (H{sub c}) represents B{sup 0} (D{sup +}), B{sup -} (D{sup 0}), B{sub s}{sup 0} (D{sub s}{sup +}), and {Lambda}{sub b}{sup 0} ({Lambda}{sub c}{sup +}). The measurements are performed with the LHCb detector using 35 pb{sup -1} of data collected at {radical}(s)=7 TeV. The ratios of branching fractions are measured to be [B(B{sup 0}{yields}D{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -})]/[B(B{sup 0}{yields}D{sup +}{pi}{sup -})]=2.38{+-}0.11{+-}0.21, [B(B{sup -}{yields}D{sup 0}{pi}{sup -}{pi}{sup +}{pi}{sup -})]/[B(B{sup -}{yields}D{sup 0}{pi}{sup -})]= 1.27{+-}0.06{+-}0.11, [B(B{sub s}{sup 0}{yields}D{sub s}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -})]/[B(B{submore » s}{sup 0}{yields}D{sub s}{sup +}{pi}{sup -})]=2.01{+-}0.37{+-}0.20, [B({Lambda}{sub b}{sup 0}{yields}{Lambda}{sub c}{sup +}{pi}{sup -} {pi}{sup +}{pi}{sup -})]/[B({Lambda}{sub b}{sup 0}{yields}{Lambda}{sub c}{sup +}{pi}{sup -})]=1.43{+-}0.16{+-}0.13 We also report measurements of partial decay rates of these decays to excited charm hadrons. These results are of comparable or higher precision than existing measurements.« less

Meson properties in magnetized quark matter

NASA Astrophysics Data System (ADS)

Wang, Ziyue; Zhuang, Pengfei

2018-02-01

We study neutral and charged meson properties in the magnetic field. Taking the bosonization method in a two-flavor Nambu-Jona-Lasinio model, we derive effective meson Lagrangian density with minimal coupling to the magnetic field, by employing derivative expansion for both the meson fields and Schwinger phases. We extract from the effective Lagrangian density the meson curvature, pole and screening masses. As the only Goldstone mode, the neutral pion controls the thermodynamics of the system and propagates the long range quark interaction. The magnetic field breaks down the space symmetry, and the quark interaction region changes from a sphere in vacuum to a ellipsoid in magnetic field.

a Partial Wave Analysis of the Reaction Negative Pion Proton ---> Positive Pion Negative Pion Neutral Pion Neutron at 8.45 Gev/c.

NASA Astrophysics Data System (ADS)

Dankowych, John Alexander

1980-06-01

We have performed an isobar model partial wave analysis (PWA) of a high statistics sample of the reaction (pi)('-)p (,(--->)) (pi)('+)(pi)('-)(pi)('0)n at 8.45 GeV/c. We present strong evidence for the existence of the unnatural parity, isoscalar (H) and isovector (A(,1)) axial-vector mesons. The intensity distributions show significant structure while the forward phase motion relative to the isospin-2 axial-vector partial wave is consistent with that expected for Breit-Wigner resonances. The A(,1) production is mainly via M = 1, natural parity exchange while the H is produced mainly in M = 0, natural parity exchange. From a Deck model fit we obtain for the A(,1) a mass of 1241 (+OR-) 80 MeV and a width of 380 (+OR-) 100 MeV; for the H we obtain a mass of 1194 (+OR-) 55 MeV and a width of 320 (+OR-) 50 MeV. In nucleon spin flip we have evidence for an isovector, pseudoscalar resonance ((pi)') under the A(,2). The natural parity states : the (omega)(IJP = 01-), the A(,2) (IJP = 12+) and the (omega)(,g )(IJP = 03-) are strong features of the data. In the IJP = 01- partial wave thre is more cross-section than that expected for just the (omega)(783) tail.

Measurements of Branching Ratios And Search for CP Violation in the Modes B0 to Rho Pi, Rho K (in French)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Laplace, Sandrine; /Paris U., VI-VII

2006-09-18

The BABAR experiment, at the PEP-II collider at SLAC, has been studying since 1999 CP violation in the B meson system. After the precise measurement of sin2{beta}, one is now concentrating on measuring the angles {alpha} and {gamma} of the unitarity triangle. The work presented in this thesis concerns the measurement of the angle {alpha} in the B{sup 0} {yields} {rho}{pi} mode.

D mesons in a magnetic field

DOE PAGES

Gubler, Philipp; Hattori, Koichi; Lee, Su Houng; ...

2016-03-15

In this paper, we investigate the mass spectra of open heavy flavor mesons in an external constant magnetic field within QCD sum rules. Spectral Ansatze on the phenomenological side are proposed in order to properly take into account mixing effects between the pseudoscalar and vector channels, and the Landau levels of charged mesons. The operator product expansion is implemented up to dimension-5 operators. As a result, we find for neutral D mesons a significant positive mass shift that goes beyond simple mixing effects. In contrast, charged D mesons are further subject to Landau level effects, which together with the mixingmore » effects almost completely saturate the mass shifts obtained in our sum rule analysis.« less

Nucleon Resonance Structure from Exclusive Meson Electroproduction with CLAS

DOE PAGES

Mokeev, Victor I.

2018-04-06

Studies of the nucleon resonance electroexcitation amplitudes in a wide range of photon virtualities offer unique information on many facets of strong QCD behind the generation of all prominent excited nucleon states of distinctively different structure. Advances in the evaluation of resonance electroexcitation amplitudes from the data measured with the CLAS detector and the future extension of these studies with the CLAS12 detector at Jefferson Lab are presented in this paper. For the first time, analyses ofmore » $$\\pi^0p$$, $$\\pi^+n$$, $$\\eta p$$, and $$\\pi^+\\pi^-p$$ electroproduction off proton channels have provided electroexcitation amplitudes of most resonances in the mass range up to 1.8 GeV and at photon virtualities $Q^2 < 5$ GeV$^2$. Consistent results on resonance electroexcitation amplitudes determined from different exclusive channels validate a credible extraction of these fundamental quantities. Studies of the resonance electroexcitation amplitudes revealed the $N^*$ structure as a complex interplay between the inner core of three dressed quarks and the external meson-baryon cloud. The successful description of the $$\\Delta(1232)3/2^+$$ and $N(1440)1/2^+$ electrocouplings achieved within the Dyson-Schwinger Equation approach under a traceable connection to the QCD Lagrangian and supported by the novel light front quark model demonstrated the relevance of dressed quarks with dynamically generated masses as an active structural component in baryons. Future experiments with the CLAS12 detector will offer insight into the structure of all prominent resonances at the highest photon virtualities, $Q^2 < 12$ GeV$^2$, ever achieved in exclusive reactions, thus addressing the most challenging problems of the Standard Model on the nature of hadron mass, quark-gluon confinement, and the emergence of nucleon resonance structures from QCD. Finally, a search for new states of hadronic matter, the so-called hybrid-baryons with glue as a structural

Nucleon Resonance Structure from Exclusive Meson Electroproduction with CLAS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mokeev, Victor I.

Studies of the nucleon resonance electroexcitation amplitudes in a wide range of photon virtualities offer unique information on many facets of strong QCD behind the generation of all prominent excited nucleon states of distinctively different structure. Advances in the evaluation of resonance electroexcitation amplitudes from the data measured with the CLAS detector and the future extension of these studies with the CLAS12 detector at Jefferson Lab are presented in this paper. For the first time, analyses ofmore » $$\\pi^0p$$, $$\\pi^+n$$, $$\\eta p$$, and $$\\pi^+\\pi^-p$$ electroproduction off proton channels have provided electroexcitation amplitudes of most resonances in the mass range up to 1.8 GeV and at photon virtualities $Q^2 < 5$ GeV$^2$. Consistent results on resonance electroexcitation amplitudes determined from different exclusive channels validate a credible extraction of these fundamental quantities. Studies of the resonance electroexcitation amplitudes revealed the $N^*$ structure as a complex interplay between the inner core of three dressed quarks and the external meson-baryon cloud. The successful description of the $$\\Delta(1232)3/2^+$$ and $N(1440)1/2^+$ electrocouplings achieved within the Dyson-Schwinger Equation approach under a traceable connection to the QCD Lagrangian and supported by the novel light front quark model demonstrated the relevance of dressed quarks with dynamically generated masses as an active structural component in baryons. Future experiments with the CLAS12 detector will offer insight into the structure of all prominent resonances at the highest photon virtualities, $Q^2 < 12$ GeV$^2$, ever achieved in exclusive reactions, thus addressing the most challenging problems of the Standard Model on the nature of hadron mass, quark-gluon confinement, and the emergence of nucleon resonance structures from QCD. Finally, a search for new states of hadronic matter, the so-called hybrid-baryons with glue as a structural

Chiral perturbation theory versus vector meson dominance in the decays ø -> ργγ and ø -> ωγγ

NASA Astrophysics Data System (ADS)

Ko, Pyungwon; Lee, Jungil; Song, H. S.

1996-02-01

It is pointed out that the radiative decays of a φ meson, φ → ϱγγ and φ → ωγγ, receive dominant contributions from the pseudoscalar ( P = η, η‧) exchanges. Using the vector meson dominance model, we find that B( φ → ϱγγ) ≈ 1.3 × 10 -4 and B( φ → ωγγ) ≈ 1.5 × 10 -5, which are mainly from the η‧ pole. Thus, these decays are well within the reach of the φ factory. Our estimates are a few orders of magnitude larger than the chiral loop contributions in the heavy vector meson chiral lagrangian, which is about (a few) ×10 -9.

Effect of unitarization on the amplitudes for the decays K{sub 1}{sup 0} {sup {yields} {pi}+{pi}-} and K{sup +} {sup {yields} {pi}+{pi}+{pi}-}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shabalin, E. P., E-mail: shabalin@itep.r

The unitarization of the amplitude for the decay process K{sub 1}{sup 0} {sup {yields} {pi}+{pi}-} and allowance for the rescattering of final-state pions in the decay process K{sup +} {sup {yields} {pi}+{pi}+{pi}-} make it possible to evaluate, by using the parameters extracted from data on K {sup {yields}}2{pi} decays, the K{sup +} {sup {yields} {pi}+{pi}+{pi}-} decay width. The result agrees with the experimental width value at a level of a few percent. Allowance for corrections for higher order terms of the momentum expansion of the amplitude for the decay process K{sup +} {sup {yields} {pi}+{pi}+{pi}-} leads to the slope-parameter valuemore » of g{sub ++-}{sup th} = 0.2182, which agrees with its experimental counterpart, g{sub ++-}{sup exp} = 0.2154 {+-} 0.0035.« less

First observation of the decays {chi}{sub cJ}{yields}{pi}{sup 0}{pi}{sup 0}{pi}{sup 0}{pi}{sup 0}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ablikim, M.; An, Z. H.; Bai, J. Z.

We present a study of the P-wave spin-triplet charmonium {chi}{sub cJ} decays (J=0, 1, 2) into {pi}{sup 0}{pi}{sup 0}{pi}{sup 0}{pi}{sup 0}. The analysis is based on 106x10{sup 6} {psi}{sup '} decays recorded with the BESIII detector at the BEPCII electron positron collider. The decay into the {pi}{sup 0}{pi}{sup 0}{pi}{sup 0}{pi}{sup 0} hadronic final state is observed for the first time. We measure the branching fractions B({chi}{sub c0}{yields}{pi}{sup 0}{pi}{sup 0}{pi}{sup 0}{pi}{sup 0})=(3.34{+-}0.06{+-}0.44)x10{sup -3}, B({chi}{sub c1}{yields}{pi}{sup 0}{pi}{sup 0}{pi}{sup 0}{pi}{sup 0})=(0.57{+-}0.03{+-}0.08)x10{sup -3}, and B({chi}{sub c2}{yields}{pi}{sup 0}{pi}{sup 0}{pi}{sup 0}{pi}{sup 0})=(1.21{+-}0.05{+-}0.16)x10{sup -3}, where the uncertainties are statistical and systematical, respectively.

Decays of bottom mesons emitting tensor mesons in the final state using the Isgur-Scora-Grinstein-Wise II model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sharma, Neelesh; Verma, R. C.; Dhir, Rohit

2011-01-01

In this paper, we investigate phenomenologically two-body weak decays of the bottom mesons emitting pseudoscalar/vector meson and a tensor meson. Form factors are obtained using the improved Isgur-Scora-Grinstein-Wise II model. Consequently, branching ratios for the Cabibbo-Kobayashi-Maskawa-favored and Cabibbo-Kobayashi-Maskawa-suppressed decays are calculated.

Antiproton-proton annihilation into light neutral meson pairs within an effective meson theory

NASA Astrophysics Data System (ADS)

Wang, Ying; Bystritskiy, Yury M.; Ahmadov, Azad I.; Tomasi-Gustafsson, Egle

2017-08-01

Antiproton-proton annihilation into light neutral mesons in the few GeV energy domain is investigated in view of a global description of the existing data and predictions for future work at the Antiproton Annihilation at Darmstadt (PANDA) experiment at the Facility for Antiproton and Ion Research (FAIR). An effective meson model earlier developed, with mesonic and baryonic degrees of freedom in s , t , and u channels, is applied here to π0π0 production. Form factors with logarithmic s and t (u ) dependencies are applied. A fair agreement with the existing angular distributions is obtained. Applying SU(3) symmetry, it is straightforward to recover the angular distributions for π0η and η η production in the same energy range. A good agreement is generally obtained with all existing data.

Electromagnetic Studies of Mesons, Nucleons, and Nuclei

DOE Office of Scientific and Technical Information (OSTI.GOV)

Baker, Oliver K.

Professor Baker was a faculty member at Hampton University in Hampton, Virginia, and, jointly, a Staff Physicist at Jefferson Lab in nearby Newport News from September 1989 to July 2006. The Department of Energy (DOE) funded the grant DE-FG02-97ER41035 Electromagnetic Studies of Mesons, Nucleons, and Nuclei, while Baker was in this joint appointment. Baker sent a closeout report on these activities to Hampton University’s Sponsored Research Office some years ago, shortly after joining Yale University in 2006. In the period around 2001, the research grant with Baker as the Principal Investigator (PI) was put under the supervision of Professor Liguangmore » Tang at Hampton University. Baker continued to pursue the research while in this join appointment, however the administrative responsibilities with the DOE and with Hampton University rested with Professor Tang after 2001, to my recollection. What is written in this document is from Baker’s memory of the research activities, which he has not pursued since joining the Yale University faculty.« less

Hadronic three-body decays of B mesons

NASA Astrophysics Data System (ADS)

Cheng, Hai-Yang

2016-04-01

Hadronic three-body decays of B mesons receive both resonant and nonresonant contributions. Dominant nonresonant contributions to tree-dominated three-body decays arise from the b → u tree transition which can be evaluated using heavy meson chiral perturbation theory valid in the soft meson limit. For penguin-dominated decays, nonresonant signals come mainly from the penguin amplitude governed by the matrix elements of scalar densities . The intermediate vector meson contributions to three-body decays are identified through the vector current, while the scalar meson resonances are mainly associated with the scalar density. We discuss inclusive and regional direct CP asymmetries. In the low mass regions of the Dalitz plot, we find that the regional CP violation is indeed largely enhanced with respect to the inclusive one.

Tissue characterization of brain tumors during and after pion radiation therapy.

PubMed

Boesiger, P; Greiner, R; Schoepflin, R E; Kann, R; Kuenzi, U

1990-01-01

Negative Pi-mesons (pions) are applied at the Paul Scherrer Institute in the radiotherapy of highly malignant gliomas using a dose escalation program. The therapy effects of 7 randomly selected patients were followed up by 62 MRI examinations. The quantification of the effects is based on the relaxation times T1 and T2, which are acquired by a new designed multi-echo multiple saturation recovery imaging technique. As a summary of the results, roughly two reaction types are observed. For both types the relaxation times increase up to two to three months after the radiation therapy. Then in one type (two patients) the T1 and T2 values of the tumors, and of the edemas surrounding the tumors, further increase, indicating an unfavorable prognosis. In the other type (five patients) the relaxation times drop down towards, or even below, their initial values, reflecting the onset of the reparation processes in the tissue. This later behaviour reflects an at least temporary control of the disease; that is, the short term prognosis for these patients is more favorable. It further can be concluded, with respect to our MR parameters, that the radiotolerance of healthy brain tissue is much higher than that of malignant glioma tissue, despite the fact that these tumors are very seldom definitively radiosensible.

Antagonism of EGFR and HER3 Enhances the Response to Inhibitors of the PI3K-Akt Pathway in Triple-Negative Breast Cancer

PubMed Central

Tao, Jessica J.; Castel, Pau; Radosevic-Robin, Nina; Elkabets, Moshe; Auricchio, Neil; Aceto, Nicola; Weitsman, Gregory; Barber, Paul; Vojnovic, Borivoj; Ellis, Haley; Morse, Natasha; Viola-Villegas, Nerissa Therese; Bosch, Ana; Juric, Dejan; Hazra, Saswati; Singh, Sharat; Kim, Phillip; Bergamaschi, Anna; Maheswaran, Shyamala; Ng, Tony; Penault-Llorca, Frédérique; Lewis, Jason S.; Carey, Lisa A.; Perou, Charles M.; Baselga, José; Scaltriti, Maurizio

2014-01-01

Both abundant epidermal growth factor receptor (EGFR or ErbB1) and high activity of the phosphatidyl-inositol 3-kinase (PI3K)–Akt pathway are common and therapeutically targeted in triple-negative breast cancer (TNBC). However, activation of another EGFR family member [human epidermal growth factor receptor 3 (HER3) (or ErbB3)] may limit the antitumor effects of these drugs. We found that TNBC cell lines cultured with the EGFR or HER3 ligand EGF or heregulin, respectively, and treated with either an Akt inhibitor (GDC-0068) or a PI3K inhibitor (GDC-0941) had increased abundance and phosphorylation of HER3. The phosphorylation of HER3 and EGFR in response to these treatments was reduced by the addition of a dual EGFR and HER3 inhibitor (MEHD7945A). MEHD7945A also decreased the phosphorylation (and activation) of EGFR and HER3 and the phosphorylation of downstream targets that occurred in response to the combination of EGFR ligands and PI3K-Akt pathway inhibitors. In culture, inhibition of the PI3K-Akt pathway combined with either MEHD7945A or knockdown of HER3 decreased cell proliferation compared with inhibition of the PI3K-Akt pathway alone. Combining either GDC-0068 or GDC-0941 with MEHD7945A inhibited the growth of xenografts derived from TNBC cell lines or from TNBC patient tumors, and this combination treatment was also more effective than combining either GDC-0068 or GDC-0941 with cetuximab, an EGFR-targeted antibody. After therapy with EGFR-targeted antibodies, some patients had residual tumors with increased HER3 abundance and EGFR/HER3 dimerization (an activating interaction). Thus, we propose that concomitant blockade of EGFR, HER3, and the PI3K-Akt pathway in TNBC should be investigated in the clinical setting. PMID:24667376

Antagonism of EGFR and HER3 enhances the response to inhibitors of the PI3K-Akt pathway in triple-negative breast cancer.

PubMed

Tao, Jessica J; Castel, Pau; Radosevic-Robin, Nina; Elkabets, Moshe; Auricchio, Neil; Aceto, Nicola; Weitsman, Gregory; Barber, Paul; Vojnovic, Borivoj; Ellis, Haley; Morse, Natasha; Viola-Villegas, Nerissa Therese; Bosch, Ana; Juric, Dejan; Hazra, Saswati; Singh, Sharat; Kim, Phillip; Bergamaschi, Anna; Maheswaran, Shyamala; Ng, Tony; Penault-Llorca, Frédérique; Lewis, Jason S; Carey, Lisa A; Perou, Charles M; Baselga, José; Scaltriti, Maurizio

2014-03-25

Both abundant epidermal growth factor receptor (EGFR or ErbB1) and high activity of the phosphatidylinositol 3-kinase (PI3K)-Akt pathway are common and therapeutically targeted in triple-negative breast cancer (TNBC). However, activation of another EGFR family member [human epidermal growth factor receptor 3 (HER3) (or ErbB3)] may limit the antitumor effects of these drugs. We found that TNBC cell lines cultured with the EGFR or HER3 ligand EGF or heregulin, respectively, and treated with either an Akt inhibitor (GDC-0068) or a PI3K inhibitor (GDC-0941) had increased abundance and phosphorylation of HER3. The phosphorylation of HER3 and EGFR in response to these treatments was reduced by the addition of a dual EGFR and HER3 inhibitor (MEHD7945A). MEHD7945A also decreased the phosphorylation (and activation) of EGFR and HER3 and the phosphorylation of downstream targets that occurred in response to the combination of EGFR ligands and PI3K-Akt pathway inhibitors. In culture, inhibition of the PI3K-Akt pathway combined with either MEHD7945A or knockdown of HER3 decreased cell proliferation compared with inhibition of the PI3K-Akt pathway alone. Combining either GDC-0068 or GDC-0941 with MEHD7945A inhibited the growth of xenografts derived from TNBC cell lines or from TNBC patient tumors, and this combination treatment was also more effective than combining either GDC-0068 or GDC-0941 with cetuximab, an EGFR-targeted antibody. After therapy with EGFR-targeted antibodies, some patients had residual tumors with increased HER3 abundance and EGFR/HER3 dimerization (an activating interaction). Thus, we propose that concomitant blockade of EGFR, HER3, and the PI3K-Akt pathway in TNBC should be investigated in the clinical setting.

GABARAPs regulate PI4P-dependent autophagosome:lysosome fusion.

PubMed

Wang, Hanzhi; Sun, Hui-Qiao; Zhu, Xiaohui; Zhang, Li; Albanesi, Joseph; Levine, Beth; Yin, Helen

2015-06-02

The Atg8 autophagy proteins are essential for autophagosome biogenesis and maturation. The γ-aminobutyric acid receptor-associated protein (GABARAP) Atg8 family is much less understood than the LC3 Atg8 family, and the relationship between the GABARAPs' previously identified roles as modulators of transmembrane protein trafficking and autophagy is not known. Here we report that GABARAPs recruit palmitoylated PI4KIIα, a lipid kinase that generates phosphatidylinositol 4-phosphate (PI4P) and binds GABARAPs, from the perinuclear Golgi region to autophagosomes to generate PI4P in situ. Depletion of either GABARAP or PI4KIIα, or overexpression of a dominant-negative kinase-dead PI4KIIα mutant, decreases autophagy flux by blocking autophagsome:lysosome fusion, resulting in the accumulation of abnormally large autophagosomes. The autophagosome defects are rescued by overexpressing PI4KIIα or by restoring intracellular PI4P through "PI4P shuttling." Importantly, PI4KIIα's role in autophagy is distinct from that of PI4KIIIβ and is independent of subsequent phosphatidylinositol 4,5 biphosphate (PIP2) generation. Thus, GABARAPs recruit PI4KIIα to autophagosomes, and PI4P generation on autophagosomes is critically important for fusion with lysosomes. Our results establish that PI4KIIα and PI4P are essential effectors of the GABARAP interactome's fusion machinery.

Renormalization group analysis of B →π form factors with B -meson light-cone sum rules

NASA Astrophysics Data System (ADS)

Shen, Yue-Long; Wei, Yan-Bing; Lü, Cai-Dian

2018-03-01

Within the framework of the B -meson light-cone sum rules, we review the calculation of radiative corrections to the three B →π transition form factors at leading power in Λ /mb. To resum large logarithmic terms, we perform the complete renormalization group evolution of the correlation function. We employ the integral transformation which diagonalizes evolution equations of the jet function and the B -meson light-cone distribution amplitude to solve these evolution equations and obtain renormalization group improved sum rules for the B →π form factors. Results of the form factors are extrapolated to the whole physical q2 region and are compared with that of other approaches. The effect of B -meson three-particle light-cone distribution amplitudes, which will contribute to the form factors at next-to-leading power in Λ /mb at tree level, is not considered in this paper.

Meson spectroscopy, quark mixing and quantum chromodynamics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Filippov, A.T.

1979-04-01

A semiphenomenological theory of the quark-antiquark meson mass spectrum is presented. Relativistic kinematic effects due to unequal quark masses and SU (3) -breaking effects in the slopes of Regge trajectories and in radially excited states are taken into account. Violation of the OZI rule is accounted for by means of a mixing matrix for the quark wave functions, which is given by QCD. To describe the dependence of the mixing parameters on the meson masses, a simple extrapolation of the QCD expressions is proposed from the ''asymptotic-freedom'' region to the ''infrared-slavery'' region. To calculate the masses and mixing angles ofmore » the pseudoscalar mesons, the condition for a minimal pion mass is proposed. The eta-meson mass is then shown to be close to its maximum. The predictions of the theory for meson masses and mixing angles are in good agreement with experiment.« less

Observation of pi+pi-pi+pi- photoproduction in ultraperipheral heavy-ion collisions at sqrt sNN = 200 GeV at the STAR detector

DOE Office of Scientific and Technical Information (OSTI.GOV)

STAR Collaboration; Abelev, Betty

We present a measurement of {pi}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -} photonuclear production in ultra-peripheral Au-Au collisions at {radical}s{sub NN} = 200 GeV from the STAR experiment. The {pi}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -} final states are observed at low transverse momentum and are accompanied by mutual nuclear excitation of the beam particles. The strong enhancement of the production cross section at low transverse momentum is consistent with coherent photoproduction. The {pi}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -} invariant mass spectrum of the coherent events exhibits a broad peak around 1540 {+-} 40 MeV/c{sup 2} with a width of 570 {+-} 60 MeV/c{sup 2},more » in agreement with the photoproduction data for the {rho}{sup 0}(1700). We do not observe a corresponding peak in the {pi}{sup +}{pi}{sup -} final state and measure an upper limit for the ratio of the branching fractions of the {rho}{sup 0}(1700) to {pi}{sup +}{pi}{sup -} and {pi}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -} of 2.5% at 90% confidence level. The ratio of {rho}{sup 0}(1700) and {rho}{sup 0}(770) coherent production cross sections is measured to be 13.4 {+-} 0.8{sub stat.} {+-} 4.4{sub syst.}%.« less

Observation of pi+ pi- pi+pi- photoproduction in ultraperipheral heavy-ion collisons at sqrt sNN = 200 GeV at the STAR Detector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abelev, B.I.; Dunlop, J.; et al. STAR Collaboration

We present a measurement of {pi}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -} photonuclear production in ultraperipheral Au-Au collisions at {radical}s{sub NN} = 200 GeV from the STAR experiment. The {pi}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -} final states are observed at low transverse momentum and are accompanied by mutual nuclear excitation of the beam particles. The strong enhancement of the production cross section at low transverse momentum is consistent with coherent photoproduction. The {pi}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -} invariant mass spectrum of the coherent events exhibits a broad peak around 1540 {+-} 40 MeV/c{sup 2} with a width of 570 {+-} 60 MeV/c{sup 2},more » in agreement with the photoproduction data for the {rho}{sup 0}(1700). We do not observe a corresponding peak in the {pi}{sup +}{pi}{sup -} final state and measure an upper limit for the ratio of the branching fractions of the {rho}{sup 0}(1700) to {pi}{sup +}{pi}{sup -} and {pi}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -} of 2.5% at 90% confidence level. The ratio of {rho}{sup 0}(1700) and {rho}{sup 0}(770) coherent production cross sections is measured to be 13.4 {+-} 0.8{sub stat.}{+-}4.4{sub syst.}%.« less

Study of the $${X^\\pm(5568)}$$ state with semileptonic decays of the $${B_s^0}$$ meson

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abazov, Victor Mukhamedovich; et al.

2017-12-29

We present a study of themore » $$X^\\pm(5568)$$ using semileptonic decays of the $$B_s^0$$ meson using the full Run II integrated luminosity of 10.4 fb$$^{-1}$$ in proton-antiproton collisions at a center of mass energy of 1.96\\,TeV collected with the D0 detector at the Fermilab Tevatron Collider. We report evidence for a narrow structure, $$X^\\pm(5568)$$, in the decay sequence $$X^\\pm(5568) \\to B_s^0 \\pi^\\pm$$ where $$B_s^0 \\rightarrow \\mu^\\mp D_s^\\pm \\, \\mathrm{X}$$, $$D_s^\\pm \\rightarrow \\phi \\pi^{\\pm}$$ which is consistent with the previous measurement by the D0 collaboration in the hadronic decay mode, $$X^\\pm(5568) \\to B^0_s \\pi^\\pm$$ where $$B^0_s \\to J/\\psi\\phi$$. The mass and width of this state are measured using a combined fit of the hadronic and semileptonic data, yielding $$m = 5566.9 ^{+3.2}_{-3.1} \\thinspace {\\rm (stat)} ^{+0.6}_{-1.2} {\\rm \\thinspace (syst)}$$\\,MeV/$c^2$, $$\\Gamma = 18.6 ^{+7.9}_{-6.1} {\\rm \\thinspace (stat)} ^{+3.5}_{-3.8} {\\rm \\thinspace (syst)} $$\\,MeV/$c^2$ with a significance of 6.7$$\\,\\sigma$$.« less

Light vector mesons in the nuclear medium

NASA Astrophysics Data System (ADS)

Wood, M. H.; Nasseripour, R.; Weygand, D. P.; Djalali, C.; Tur, C.; Mosel, U.; Muehlich, P.; Adams, G.; Amaryan, M. J.; Ambrozewicz, P.; Anghinolfi, M.; Asryan, G.; Avakian, H.; Bagdasaryan, H.; Baillie, N.; Ball, J. P.; Baltzell, N. A.; Barrow, S.; Battaglieri, M.; Bedlinskiy, I.; Bektasoglu, M.; Bellis, M.; Benmouna, N.; Berman, B. L.; Biselli, A. S.; Blaszczyk, L.; Bouchigny, S.; Boiarinov, S.; Bradford, R.; Branford, D.; Briscoe, W. J.; Brooks, W. K.; Burkert, V. D.; Butuceanu, C.; Calarco, J. R.; Careccia, S. L.; Carman, D. S.; Carnahan, B.; Casey, L.; Chen, S.; Cheng, L.; Cole, P. L.; Collins, P.; Coltharp, P.; Crabb, D.; Crannell, H.; Crede, V.; Cummings, J. P.; Dashyan, N.; de Vita, R.; de Sanctis, E.; Degtyarenko, P. V.; Denizli, H.; Dennis, L.; Deur, A.; Dharmawardane, K. V.; Dickson, R.; Dodge, G. E.; Doughty, D.; Dugger, M.; Dytman, S.; Dzyubak, O. P.; Egiyan, H.; Egiyan, K. S.; El Fassi, L.; Elouadrhiri, L.; Eugenio, P.; Fedotov, G.; Feldman, G.; Feuerbach, R. J.; Fradi, A.; Funsten, H.; Garçon, M.; Gavalian, G.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Goetz, J. T.; Gordon, C. I. O.; Gothe, R. W.; Griffioen, K. A.; Guidal, M.; Guler, N.; Guo, L.; Gyurjyan, V.; Hadjidakis, C.; Hafidi, K.; Hakobyan, H.; Hakobyan, R. S.; Hanretty, C.; Hardie, J.; Hassall, N.; Hersman, F. W.; Hicks, K.; Hleiqawi, I.; Holtrop, M.; Hyde-Wright, C. E.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Isupov, E. L.; Ito, M. M.; Jenkins, D.; Jo, H. S.; Johnstone, J. R.; Joo, K.; Juengst, H. G.; Kalantarians, N.; Kellie, J. D.; Khandaker, M.; Khetarpal, P.; Kim, W.; Klein, A.; Klein, F. J.; Klimenko, A. V.; Kossov, M.; Krahn, Z.; Kramer, L. H.; Kubarovsky, V.; Kuhn, J.; Kuhn, S. E.; Kuleshov, S. V.; Lachniet, J.; Laget, J. M.; Langheinrich, J.; Lawrence, D.; Li, Ji; Livingston, K.; Lu, H. Y.; MacCormick, M.; Markov, N.; Mattione, P.; McAleer, S.; McKinnon, B.; McNabb, J. W. C.; Mecking, B. A.; Mehrabyan, S.; Melone, J. J.; Mestayer, M. D.; Meyer, C. A.; Mibe, T.; Mikhailov, K.; Minehart, R.; Mirazita, M.; Miskimen, R.; Mokeev, V.; Moriya, K.; Morrow, S. A.; Moteabbed, M.; Mueller, J.; Munevar, E.; Mutchler, G. S.; Nadel-Turonski, P.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Niczyporuk, B. B.; Niroula, M. R.; Niyazov, R. A.; Nozar, M.; Osipenko, M.; Ostrovidov, A. I.; Park, K.; Pasyuk, E.; Paterson, C.; Pereira, S. Anefalos; Pierce, J.; Pivnyuk, N.; Pocanic, D.; Pogorelko, O.; Pozdniakov, S.; Preedom, B. M.; Price, J. W.; Prok, Y.; Protopopescu, D.; Raue, B. A.; Riccardi, G.; Ricco, G.; Ripani, M.; Ritchie, B. G.; Ronchetti, F.; Rosner, G.; Rossi, P.; Sabatié, F.; Salamanca, J.; Salgado, C.; Santoro, J. P.; Sapunenko, V.; Schumacher, R. A.; Serov, V. S.; Sharabian, Y. G.; Sharov, D.; Shvedunov, N. V.; Smith, E. S.; Smith, L. C.; Sober, D. I.; Sokhan, D.; Stavinsky, A.; Stepanyan, S.; Stepanyan, S. S.; Stokes, B. E.; Stoler, P.; Strakovsky, I. I.; Strauch, S.; Taiuti, M.; Tedeschi, D. J.; Tkabladze, A.; Tkachenko, S.; Todor, L.; Ungaro, M.; Vineyard, M. F.; Vlassov, A. V.; Watts, D. P.; Weinstein, L. B.; Williams, M.; Wolin, E.; Yegneswaran, A.; Zana, L.; Zhang, B.; Zhang, J.; Zhao, B.; Zhao, Z. W.

2008-07-01

The light vector mesons (ρ,ω, and ϕ) were produced in deuterium, carbon, titanium, and iron targets in a search for possible in-medium modifications to the properties of the ρ meson at normal nuclear densities and zero temperature. The vector mesons were detected with the CEBAF Large Acceptance Spectrometer (CLAS) via their decays to e+e-. The rare leptonic decay was chosen to reduce final-state interactions. A combinatorial background was subtracted from the invariant mass spectra using a well-established event-mixing technique. The ρ-meson mass spectrum was extracted after the ω and ϕ signals were removed in a nearly model-independent way. Comparisons were made between the ρ mass spectra from the heavy targets (A>2) with the mass spectrum extracted from the deuterium target. With respect to the ρ-meson mass, we obtain a small shift compatible with zero. Also, we measure widths consistent with standard nuclear many-body effects such as collisional broadening and Fermi motion.

Measurements of the exclusive decays of the upsilon(5S) to meson final states and improved B(s)* mass measurement.

PubMed

Aquines, O; Li, Z; Lopez, A; Mendez, H; Ramirez, J; Huang, G S; Miller, D H; Pavlunin, V; Sanghi, B; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Coan, T E; Gao, Y S; Liu, F; Stroynowski, R; Artuso, M; Blusk, S; Butt, J; Li, J; Menaa, N; Mountain, R; Nisar, S; Randrianarivony, K; Redjimi, R; Sia, R; Skwarnicki, T; Stone, S; Wang, J C; Zhang, K; Csorna, S E; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Asner, D M; Edwards, K W; Briere, R A; Brock, I; Chen, J; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Adam, N E; Alexander, J P; Berkelman, K; Cassel, D G; Duboscq, J E; Ecklund, K M; Ehrlich, R; Fields, L; Galik, R S; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Meyer, T O; Onyisi, P U E; Patterson, J R; Peterson, D; Phillips, E A; Pivarski, J; Riley, D; Ryd, A; Sadoff, A J; Schwarthoff, H; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Weinberger, M; Athar, S B; Avery, P; Breva-Newell, L; Patel, R; Potlia, V; Stoeck, H; Yelton, J; Rubin, P; Cawlfield, C; Eisenstein, B I; Karliner, I; Kim, D; Lowrey, N; Naik, P; Sedlack, C; Selen, M; White, E J; Wiss, J; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Gong, D T; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Smith, A; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A; Zweber, P; Ernst, J; Arms, K; Severini, H; Dytman, S A; Love, W; Mehrabyan, S; Savinov, V

2006-04-21

Using 420 pb(-1) of data collected on the upsilon(5S) resonance with the CLEO III detector, we reconstruct B mesons in 25 exclusive decay channels to measure or set upper limits on the decay rate of upsilon(5S) into B meson final states. We measure the inclusive B cross section to be sigma(upsilon(5S) --> BB(X)) = (0.177 +/- 0.030 +/- 0.016) nb and make the first measurements of the production rates of sigma(upsilon(5S) --> B*B*) = (0.131 +/- 0.025 +/- 0.014) nb and sigma(upsilon(5S) --> BB*) = (0.043 +/- 0.016 +/- 0.006) nb, respectively. We set 90% confidence level limits of sigma(upsilon(5S) -->BB) < 0.038 nb, sigma(upsilon(5S) --> B(*)B(*)pi) < 0.055 nb and sigma(upsilon(5S) --> BBpipi) < 0.024 nb. We also extract the most precise value of the B(s)* mass to date, M(B(s)*) = (5411.7 +/- 1.6 +/- 0.6) MeV/c2.

$B$- and $D$-meson leptonic decay constants from four-flavor lattice QCD

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bazavov, A.; Bernard, C.; Brown, N.

We calculate the leptonic decay constants of heavy-light pseudoscalar mesons with charm and bottom quarks in lattice quantum chromodynamics on four-flavor QCD gauge-field configurations with dynamicalmore » $u$, $d$, $s$, and $c$ quarks. We analyze over twenty isospin-symmetric ensembles with six lattice spacings down to $$a\\approx 0.03$$~fm and several values of the light-quark mass down to the physical value $$\\frac{1}{2}(m_u+m_d)$$. We employ the highly-improved staggered-quark (HISQ) action for the sea and valence quarks; on the finest lattice spacings, discretization errors are sufficiently small that we can calculate the $B$-meson decay constants with the HISQ action for the first time directly at the physical $b$-quark mass. We obtain the most precise determinations to-date of the $D$- and $B$-meson decay constants and their ratios, $$f_{D^+} = 212.6 (0.5)$$~MeV, $$f_{D_s} = 249.8(0.4)$$~MeV, $$f_{D_s}/f_{D^+} = 1.1749(11)$$, $$f_{B^+} = 189.4(1.4)$$~MeV, $$f_{B_s} = 230.7(1.2)$$~MeV, $$f_{B_s}/f_{B^+} = 1.2180(49)$$, where the errors include statistical and all systematic uncertainties. Our results for the $B$-meson decay constants are three times more precise than the previous best lattice-QCD calculations, and bring the QCD errors in the Standard-Model predictions for the rare leptonic decays $$\\overline{\\mathcal{B}}(B_s \\to \\mu^+\\mu^-) = 3.65(11) \\times 10^{-9}$$, $$\\overline{\\mathcal{B}}(B^0 \\to \\mu^+\\mu^-) = 1.00(3) \\times 10^{-11}$$, and $$\\overline{\\mathcal{B}}(B^0 \\to \\mu^+\\mu^-)/\\overline{\\mathcal{B}}(B_s \\to \\mu^+\\mu^-) = 0.00264(7)$$ to well below other sources of uncertainty. As a byproduct of our analysis, we also update our previously published results for the light-quark-mass ratios and the scale-setting quantities $$f_{p4s}$$, $$M_{p4s}$$, and $$R_{p4s}$$. We obtain the most precise lattice-QCD determination to date of the ratio $$f_{K^+}/f_{\\pi^+} = 1.1950(^{+15}_{-22})$$~MeV.« less

Exotic Meson Results from BNL E852

NASA Astrophysics Data System (ADS)

Manak, Joseph J.

1998-10-01

Results from BNL experiment 852 on exotic (non-q\\overlineq) meson production are presented. Production of final states with J^PC = 1^-+ is observed in π^-p interactions at 18 GeV/c in the ηπ^-, ρπ^- and η^'π^- channels. Since such states are manifestly exotic if they are resonant, we describe amplitude analyses which use the interference between these states and other well known states to measure the phase behavior of the J^PC = 1^-+ amplitudes. The analyses show that, in addition to the previously reported(D.R. Thompson et al.), Phys. Rev. Lett. 79, 1630 (1997) evidence for an exotic meson in the ηπ^- channel, there is strong evidence for a second exotic meson decaying to ρπ^- with a mass of M=1593 ±8^+29_-47 MeV/c^2 and a width of Γ=168 ±20^+150_-12 MeV/c^2. We also show that the η^'π^- system is dominated by J^PC = 1^-+ production and we use those data to determine decay branching ratios for the exotic mesons. Such measurements are expected to be crucial in determining the constituent nature of the exotic mesons - that is, whether they are consistent with being hybrid mesons or four-quark states.

Inhibiting the phosphatidylinositide 3-kinase pathway blocks radiation-induced metastasis associated with Rho-GTPase and Hypoxia-inducible factor-1 activity.

PubMed

Burrows, Natalie; Telfer, Brian; Brabant, Georg; Williams, Kaye J

2013-09-01

Undifferentiated follicular and anaplastic thyroid tumours often respond poorly to radiotherapy and show increased metastatic potential. We evaluated radiation-induced effects on metastasis in thyroid carcinoma cells and tumours, mechanistically focusing on phosphatidylinositide 3-kinase (PI3K) and associated pathways. Migration was analysed in follicular (FTC133) and anaplastic (8505c) cells following radiotherapy (0-6 Gray) with concomitant pharmacological (GDC-0941) or genetic inhibition of PI3K. Hypoxia-inducible factor-1 (HIF-1)-activity was measured using luciferase reporter assays and was inhibited using a dominant-negative variant. Activation and subcellular localisation of target proteins were assessed via Western blot and immunofluorescence. In vivo studies used FTC133 xenografts with metastatic lung dissemination assessed ex vivo. Radiation induced migration in a HIF-dependent manner in FTC133 cells but decreased migration in 8505c's. Post-radiation HIF-activity correlated with migratory phenotype. PI3K-targeting inhibited migration under basal and irradiated conditions through inhibition of HIF-1α, Rho-GTPase expression/activity and localisation whilst having little effect on src/FAK. In vivo, radiation induced PI3K, HIF, Rho-GTPases and src but only PI3K, HIF and Rho-GTPases were inhibited by GDC-0941. Co-treatment with GDC-0941 and radiation significantly reduced metastatic dissemination versus radiotherapy alone. Radiation modifies metastatic characteristics of thyroid carcinoma cells, which can be successfully inhibited by targeting PI3K using GDC-0941 in vitro and in vivo. Copyright © 2013 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

Consensus model for identification of novel PI3K inhibitors in large chemical library.

PubMed

Liew, Chin Yee; Ma, Xiao Hua; Yap, Chun Wei

2010-02-01

Phosphoinositide 3-kinases (PI3Ks) inhibitors have treatment potential for cancer, diabetes, cardiovascular disease, chronic inflammation and asthma. A consensus model consisting of three base classifiers (AODE, kNN, and SVM) trained with 1,283 positive compounds (PI3K inhibitors), 16 negative compounds (PI3K non-inhibitors) and 64,078 generated putative negatives was developed for predicting compounds with PI3K inhibitory activity of IC(50) < or = 10 microM. The consensus model has an estimated false positive rate of 0.75%. Nine novel potential inhibitors were identified using the consensus model and several of these contain structural features that are consistent with those found to be important for PI3K inhibitory activities. An advantage of the current model is that it does not require knowledge of 3D structural information of the various PI3K isoforms, which is not readily available for all isoforms.

Consensus model for identification of novel PI3K inhibitors in large chemical library

NASA Astrophysics Data System (ADS)

Liew, Chin Yee; Ma, Xiao Hua; Yap, Chun Wei

2010-02-01

Phosphoinositide 3-kinases (PI3Ks) inhibitors have treatment potential for cancer, diabetes, cardiovascular disease, chronic inflammation and asthma. A consensus model consisting of three base classifiers (AODE, kNN, and SVM) trained with 1,283 positive compounds (PI3K inhibitors), 16 negative compounds (PI3K non-inhibitors) and 64,078 generated putative negatives was developed for predicting compounds with PI3K inhibitory activity of IC50 ≤ 10 μM. The consensus model has an estimated false positive rate of 0.75%. Nine novel potential inhibitors were identified using the consensus model and several of these contain structural features that are consistent with those found to be important for PI3K inhibitory activities. An advantage of the current model is that it does not require knowledge of 3D structural information of the various PI3K isoforms, which is not readily available for all isoforms.

Antiproton-proton annihilation into charged light meson pairs within effective meson theory

NASA Astrophysics Data System (ADS)

Wang, Ying; Bystritskiy, Yury M.; Tomasi-Gustafsson, Egle

2017-04-01

We revisit antiproton-proton annihilation into light mesons in the energy domain relevant to the antiproton annihilation at Darmstadt (PANDA) experiment at the GSI Facility for Antiproton and Ion Research (FAIR) [2.25 (1.5 ) ≤√{s }(pL) ≤5.47 (15 ) GeV (GeV /c ) where √{s }(pL) is the total energy (the beam momentum in the laboratory frame)]. An effective meson model is developed, with mesonic and baryonic degrees of freedom. Form factors are added to take into account the composite nature of the interacting hadrons. A comparison is made with the existing data for charged pion pair production and predictions for angular distributions and energy dependence in the range 3.362 (5 ) ≤√{s }(pL) ≤4.559 (10.1 ) GeV (GeV /c ). The model is applied to π±p elastic scattering, using crossing symmetry, and to charged kaon pair production, on the basis of SU(3) symmetry. In all cases the results illustrate a nice agreement with the data.

Local-duality QCD sum rules for strong isospin breaking in the decay constants of heavy-light mesons.

PubMed

Lucha, Wolfgang; Melikhov, Dmitri; Simula, Silvano

2018-01-01

We discuss the leptonic decay constants of heavy-light mesons by means of Borel QCD sum rules in the local-duality (LD) limit of infinitely large Borel mass parameter. In this limit, for an appropriate choice of the invariant structures in the QCD correlation functions, all vacuum-condensate contributions vanish and all nonperturbative effects are contained in only one quantity, the effective threshold. We study properties of the LD effective thresholds in the limits of large heavy-quark mass [Formula: see text] and small light-quark mass [Formula: see text]. In the heavy-quark limit, we clarify the role played by the radiative corrections in the effective threshold for reproducing the pQCD expansion of the decay constants of pseudoscalar and vector mesons. We show that the dependence of the meson decay constants on [Formula: see text] arises predominantly (at the level of 70-80%) from the calculable [Formula: see text]-dependence of the perturbative spectral densities. Making use of the lattice QCD results for the decay constants of nonstrange and strange pseudoscalar and vector heavy mesons, we obtain solid predictions for the decay constants of heavy-light mesons as functions of [Formula: see text] in the range from a few to 100 MeV and evaluate the corresponding strong isospin-breaking effects: [Formula: see text], [Formula: see text], [Formula: see text], [Formula: see text].

Exposure to Ionizing Radiation Causes Long-Term Increase in Serum Estradiol and Activation of PI3K-Akt Signaling Pathway in Mouse Mammary Gland

DOE Office of Scientific and Technical Information (OSTI.GOV)

Suman, Shubhankar; Johnson, Michael D.; Fornace, Albert J.

Purpose: Exposure to ionizing radiation is an established risk factor for breast cancer. Radiation exposure during infancy, childhood, and adolescence confers the highest risk. Although radiation is a proven mammary carcinogen, it remains unclear where it acts in the complex multistage process of breast cancer development. In this study, we investigated the long-term pathophysiologic effects of ionizing radiation at a dose (2 Gy) relevant to fractionated radiotherapy. Methods and Materials: Adolescent (6-8 weeks old; n = 10) female C57BL/6J mice were exposed to 2 Gy total body {gamma}-radiation, the mammary glands were surgically removed, and serum and urine samples weremore » collected 2 and 12 months after exposure. Molecular pathways involving estrogen receptor-{alpha} (ER{alpha}) and phosphatidylinositol-3-OH kinase (PI3K)-Akt signaling were investigated by immunohistochemistry and Western blot. Results: Serum estrogen and urinary levels of the oncogenic estrogen metabolite (16{alpha}OHE1) were significantly increased in irradiated animals. Immunostaining for the cellular proliferative marker Ki-67 and cyclin-D1 showed increased nuclear accumulation in sections of mammary glands from irradiated vs. control mice. Marked increase in p85{alpha}, a regulatory sub-unit of the PI3K was associated with increase in Akt, phospho-Akt, phospho-BAD, phospho-mTOR, and c-Myc in irradiated samples. Persistent increase in nuclear ER{alpha} in mammary tissues 2 and 12 months after radiation exposure was also observed. Conclusions: Taken together, our data not only support epidemiologic observations associating radiation and breast cancer but also, specify molecular events that could be involved in radiation-induced breast cancer.« less

Search for Medium Modifications of the ρ Meson

NASA Astrophysics Data System (ADS)

Nasseripour, R.; Wood, M. H.; Djalali, C.; Weygand, D. P.; Tur, C.; Mosel, U.; Muehlich, P.; Adams, G.; Amaryan, M. J.; Ambrozewicz, P.; Anghinolfi, M.; Asryan, G.; Avakian, H.; Bagdasaryan, H.; Baillie, N.; Ball, J. P.; Baltzell, N. A.; Barrow, S.; Battaglieri, M.; Bedlinskiy, I.; Bektasoglu, M.; Bellis, M.; Benmouna, N.; Berman, B. L.; Biselli, A. S.; Blaszczyk, L.; Bouchigny, S.; Boiarinov, S.; Bradford, R.; Branford, D.; Briscoe, W. J.; Brooks, W. K.; Bültmann, S.; Burkert, V. D.; Butuceanu, C.; Calarco, J. R.; Careccia, S. L.; Carman, D. S.; Carnahan, B.; Casey, L.; Chen, S.; Cole, P. L.; Collins, P.; Coltharp, P.; Crabb, D.; Crannell, H.; Crede, V.; Cummings, J. P.; Dashyan, N.; de Masi, R.; de Vita, R.; de Sanctis, E.; Degtyarenko, P. V.; Denizli, H.; Dennis, L.; Deur, A.; Dharmawardane, K. V.; Dickson, R.; Dodge, G. E.; Doughty, D.; Dugger, M.; Dytman, S.; Dzyubak, O. P.; Egiyan, H.; Egiyan, K. S.; El Fassi, L.; Elouadrhiri, L.; Eugenio, P.; Fedotov, G.; Feldman, G.; Feuerbach, R. J.; Funsten, H.; Garçon, M.; Gavalian, G.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Goetz, J. T.; Gordon, C. I. O.; Gothe, R. W.; Griffioen, K. A.; Guidal, M.; Guler, N.; Guo, L.; Gyurjyan, V.; Hadjidakis, C.; Hafidi, K.; Hakobyan, H.; Hakobyan, R. S.; Hanretty, C.; Hardie, J.; Hersman, F. W.; Hicks, K.; Hleiqawi, I.; Holtrop, M.; Hyde-Wright, C. E.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Isupov, E. L.; Ito, M. M.; Jenkins, D.; Jo, H. S.; Johnstone, J. R.; Joo, K.; Juengst, H. G.; Kalantarians, N.; Kellie, J. D.; Khandaker, M.; Kim, W.; Klein, A.; Klein, F. J.; Klimenko, A. V.; Kossov, M.; Krahn, Z.; Kramer, L. H.; Kubarovsky, V.; Kuhn, J.; Kuhn, S. E.; Kuleshov, S. V.; Lachniet, J.; Laget, J. M.; Langheinrich, J.; Lawrence, D.; Li, Ji; Livingston, K.; Lu, H. Y.; MacCormick, M.; Markov, N.; Mattione, P.; McAleer, S.; McKinnon, B.; McNabb, J. W. C.; Mecking, B. A.; Mehrabyan, S.; Melone, J. J.; Mestayer, M. D.; Meyer, C. A.; Mibe, T.; Mikhailov, K.; Minehart, R.; Mirazita, M.; Miskimen, R.; Mokeev, V.; Moriya, K.; Morrow, S. A.; Moteabbed, M.; Mueller, J.; Munevar, E.; Mutchler, G. S.; Nadel-Turonski, P.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Niczyporuk, B. B.; Niroula, M. R.; Niyazov, R. A.; Nozar, M.; Osipenko, M.; Ostrovidov, A. I.; Park, K.; Pasyuk, E.; Paterson, C.; Pereira, S. Anefalos; Pierce, J.; Pivnyuk, N.; Pocanic, D.; Pogorelko, O.; Pozdniakov, S.; Preedom, B. M.; Price, J. W.; Prok, Y.; Protopopescu, D.; Raue, B. A.; Riccardi, G.; Ricco, G.; Ripani, M.; Ritchie, B. G.; Ronchetti, F.; Rosner, G.; Rossi, P.; Sabatié, F.; Salamanca, J.; Salgado, C.; Santoro, J. P.; Sapunenko, V.; Schumacher, R. A.; Serov, V. S.; Sharabian, Y. G.; Sharov, D.; Shvedunov, N. V.; Smith, E. S.; Smith, L. C.; Sober, D. I.; Sokhan, D.; Stavinsky, A.; Stepanyan, S. S.; Stepanyan, S.; Stokes, B. E.; Stoler, P.; Strakovsky, I. I.; Strauch, S.; Taiuti, M.; Tedeschi, D. J.; Tkabladze, A.; Tkachenko, S.; Todor, L.; Ungaro, M.; Vineyard, M. F.; Vlassov, A. V.; Watts, D. P.; Weinstein, L. B.; Williams, M.; Wolin, E.; Yegneswaran, A.; Zana, L.; Zhang, B.; Zhang, J.; Zhao, B.; Zhao, Z. W.

2007-12-01

The photoproduction of vector mesons on various nuclei has been studied using the CLAS detector at Jefferson Laboratory. The vector mesons, ρ, ω, and ϕ, are observed via their decay to e+e-, in order to reduce the effects of final-state interactions in the nucleus. Of particular interest are possible in-medium effects on the properties of the ρ meson. The ρ mass spectrum is extracted from the data on various nuclei, H2, C, Fe, and Ti. We observe no significant mass shift and some broadening consistent with expected collisional broadening for the ρ meson.

Spectroscopy, decay properties and Regge trajectories of the B and Bs mesons

NASA Astrophysics Data System (ADS)

Kher, Virendrasinh; Devlani, Nayneshkumar; Rai, Ajay Kumar

2017-09-01

A Gaussian wave function is used for detailed study of the mass spectra of the B and BS mesons using a Cornell potential incorporated with a 𝒪(1/m) correction in the potential energy term and expansion of the kinetic energy term up to 𝒪(p10) for relativistic correction of the Hamiltonian. The predicted excited states for the B and Bs mesons are in very good agreement with results obtained by experiment. We assign B2(5747) and Bs2(5840) as the 13P2 state, B1(5721) and Bs1(5830) as the 1P1 state, B0(5732) as the 13P0 state, Bs1(5850) as the state and B(5970) as the 23S1 state. We investigate the Regge trajectories in the (J,M2) and (nr,M2) planes with their corresponding parameters. The branching ratios for leptonic and radiative-leptonic decays are estimated for the B and BS mesons. Our results are in good agreement with experimental observations as well as outcomes of other theoretical models. A. K. Rai acknowledges the financial support extended by the Department of Science of Technology, India under SERB fast track scheme SR/FTP /PS-152/2012

Enhanced production of ψ (2 S ) mesons in heavy ion collisions

NASA Astrophysics Data System (ADS)

Cho, Sungtae

2015-05-01

I study the production of a ψ (2 S ) meson in heavy ion collisions. I evaluate Wigner functions for the ψ (2 S ) meson using both Gaussian and Coulomb wave functions, and investigate the wave function dependence in the ψ (2 S ) meson production by recombination of charm and anticharm quarks. The enhanced transverse momentum distribution of ψ (2 S ) mesons compared to that of J /ψ mesons, originated from wave function distributions of the ψ (2 S ) and J /ψ meson in momentum space, provides a plausible explanation for the recent measurement of the nuclear modification factor ratio between the ψ (2 S ) and J /ψ meson.

Phosphate (Pi)-regulated heterodimerization of the high-affinity sodium-dependent Pi transporters PiT1/Slc20a1 and PiT2/Slc20a2 underlies extracellular Pi sensing independently of Pi uptake.

PubMed

Bon, Nina; Couasnay, Greig; Bourgine, Annabelle; Sourice, Sophie; Beck-Cormier, Sarah; Guicheux, Jérôme; Beck, Laurent

2018-02-09

Extracellular phosphate (P i ) can act as a signaling molecule that directly alters gene expression and cellular physiology. The ability of cells or organisms to detect changes in extracellular P i levels implies the existence of a P i -sensing mechanism that signals to the body or individual cell. However, unlike in prokaryotes, yeasts, and plants, the molecular players involved in P i sensing in mammals remain unknown. In this study, we investigated the involvement of the high-affinity, sodium-dependent P i transporters PiT1 and PiT2 in mediating P i signaling in skeletal cells. We found that deletion of PiT1 or PiT2 blunted the P i -dependent ERK1/2-mediated phosphorylation and subsequent gene up-regulation of the mineralization inhibitors matrix Gla protein and osteopontin. This result suggested that both PiTs are necessary for P i signaling. Moreover, the ERK1/2 phosphorylation could be rescued by overexpressing P i transport-deficient PiT mutants. Using cross-linking and bioluminescence resonance energy transfer approaches, we found that PiT1 and PiT2 form high-abundance homodimers and P i -regulated low-abundance heterodimers. Interestingly, in the absence of sodium-dependent P i transport activity, the PiT1-PiT2 heterodimerization was still regulated by extracellular P i levels. Of note, when two putative P i -binding residues, Ser-128 (in PiT1) and Ser-113 (in PiT2), were substituted with alanine, the PiT1-PiT2 heterodimerization was no longer regulated by extracellular P i These observations suggested that P i binding rather than P i uptake may be the key factor in mediating P i signaling through the PiT proteins. Taken together, these results demonstrate that P i -regulated PiT1-PiT2 heterodimerization mediates P i sensing independently of P i uptake. © 2018 by The American Society for Biochemistry and Molecular Biology, Inc.

Mesons in strong magnetic fields: (I) General analyses

DOE PAGES

Hattori, Koichi; Kojo, Toru; Su, Nan

2016-03-21

Here, we study properties of neutral and charged mesons in strong magnetic fields |eB| >> Λ 2 QCD with Λ QCD being the QCD renormalization scale. Assuming long-range interactions, we examine magnetic-field dependences of various quantities such as the constituent quark mass, chiral condensate, meson spectra, and meson wavefunctions by analyzing the Schwinger–Dyson and Bethe–Salpeter equations. Based on the density of states obtained from these analyses, we extend the hadron resonance gas (HRG) model to investigate thermodynamics at large B. As B increases the meson energy behaves as a slowly growing function of the meson's transverse momenta, and thus amore » large number of meson states is accommodated in the low energy domain; the density of states at low temperature is proportional to B 2. This extended transverse phase space in the infrared regime significantly enhances the HRG pressure at finite temperature, so that the system reaches the percolation or chiral restoration regime at lower temperature compared to the case without a magnetic field; this simple picture would offer a gauge invariant and intuitive explanation of the inverse magnetic catalysis.« less

Reduction of the K* meson abundance in heavy ion collisions

NASA Astrophysics Data System (ADS)

Cho, Sungtae; Lee, Su Houng

2018-03-01

We study the K* meson reduction in heavy-ion collisions by focusing on the hadronic effects on the K* meson abundance. We evaluate the absorption cross sections of the K* and K meson by light mesons in the hadronic matter, and further investigate the variation in the meson abundances for both particles during the hadronic stage of heavy-ion collisions. We show how the interplay between the interaction of the K* meson and kaon with light mesons in the hadronic medium determines the final yield difference of the statistical hadronization model to the experimental measurements. For the central Au+Au collision at √{sN N}=200 GeV, we find that the K*/K yield ratio at chemical freeze-out decreases by 37 % during the expansion of the hadronic matter, resulting in the final ratio comparable to STAR measurements of 0.23 ±0.05 .

String splitting and strong coupling meson decay.

PubMed

Cotrone, A L; Martucci, L; Troost, W

2006-04-14

We study the decay of high spin mesons using the gauge-string theory correspondence. The rate of the process is calculated by studying the splitting of a macroscopic string intersecting a D-brane. The result is applied to the decay of mesons in N=4 super Yang-Mills theory with a small number of flavors and in a gravity dual of large N QCD. In QCD the decay of high spin mesons is found to be heavily suppressed in the regime of validity of the supergravity description.

Exclusive Central pi+pi- production in CDF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Albrow, Michael; Swiech, Artur; Zurek, Maria

2013-10-14

Using the Collider Detector at Fermilab, CDF, we have measured exclusive pi+pi- production at sqrt(s) = 900 GeV and 1960 GeV. The pi+pi- pair is central, |y| < 1.0, and there are no other particles detected in |eta| < 5.9. We discuss the mass spectrum, showing f0(980) and f2(1270) resonances, s-dependence, pT-dependence, and angular distributions.

Vector Meson Photoproduction on Nuclei

NASA Astrophysics Data System (ADS)

Djalali, Chaden

2011-10-01

Chiral symmetry, which is spontaneously broken in vacuum, is predicted to be partially restored in ordinary nuclear matter. The properties of vector mesons, such as their masses and/or widths are expected to change in the medium. The photoproduction reaction off nuclei is a very clean way of producing the ρ, ω and φ mesons, and detect them via their hadronic or leptonic decays. The leptonic decay to e+e- has a small branching ratio but has the advantage of being free from final state interactions. One critical aspect in all these experiments is the correct determination of the shape and magnitude of the combinatorial background. The in-medium mass distributions and yields are compared to those measured in vacuum. No significant shift is observed in the masses of the mesons, however substantial increase in their widths is reported.

First Observation of the Cabibbo-suppressed Decays Xi+(c) ---> Sigma+ pi- pi+ and Xi+(c) ---> Sigma- pi+ pi+ and Measurement of their Branching Ratios

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vazquez-Jauregui, E.; /San Luis Potosi U.; Engelfried, J.

The authors report the first observation of two Cabibbo-suppressed decay modes, {Xi}{sub c}{sup +} {yields} {Sigma}{sup +}{pi}{sup -}{pi}{sup +} and {Xi}{sub c}{sup +} {yields} {Sigma}{sup -} {pi}{sup +}{pi}{sup +}. They observe 56 {+-} 13 over a background of 21, and 23 {+-} 7 over a background of 12 events, respectively, for the signals. The data were accumulated using the SELEX spectrometer during the 1996-1997 fixed target run at Fermilab, chiefly from a 600 GeV/c {Sigma}{sup -} beam. The branching ratios of the decays relative to the Cabibbo-favored {Xi}{sub c}{sup +} {yields} {Xi}{sup -}{pi}{sup +}{pi}{sup +} are measured to be B({Xi}{submore » c}{sup +} {yields} {Sigma}{sup +}{pi}{sup -}{pi}{sup +})/B({xi}{sub c}{sup +} {yields} {Xi}{sup -} {pi}{sup +}{pi}{sup +}) = 0.50 {+-} 0.20, and B({Xi}{sub c}{sup +} {yields} {Sigma}{sup -}{pi}{sup +}{pi}{sup +})/B({Xi}{sub c}{sup +} {yields} {Xi}{sup -}{pi}{sup +}{pi}{sup +}) = 0.23 {+-} 0.11, respectively. They also report branching ratios for the same decay modes of the {Lambda}{sub c}{sup +} relative to {Lambda}{sub c}{sup +} {yields} pK{sup -}{pi}{sup +}.« less

Large electroweak penguin contribution in B{yields}K{pi} and {pi}{pi} decay modes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mishima, Satoshi; Yoshikawa, Tadashi

2004-11-01

We discuss a possibility of large electroweak penguin contribution in B{yields}K{pi} and {pi}{pi} from recent experimental data. The experimental data may be suggesting that there are some discrepancies between the data and theoretical estimation in the branching ratios of them. In B{yields}K{pi} decays, to explain it, a large electroweak penguin contribution and large strong phase differences seem to be needed. The contributions should appear also in B{yields}{pi}{pi}. We show, as an example, a solution to solve the discrepancies in both B{yields}K{pi} and B{yields}{pi}{pi}. However the magnitude of the parameters and the strong phase estimated from experimental data are quite largemore » compared with the theoretical estimations. It may be suggesting some new physics effects are included in these processes. We will have to discuss about the dependence of the new physics. To explain both modes at once, we may need large electroweak penguin contribution with new weak phases and some SU(3) breaking effects by new physics in both QCD and electroweak penguin-type processes.« less

Meson Spectroscopy in the Light Quark Sector

NASA Astrophysics Data System (ADS)

De Vita, R.

2014-03-01

Understanding the hadron spectrum is one of the fundamental issues in modern particle physics. We know that existing hadron configurations include baryons, made of three quarks, and mesons, made of quark-antiquark pairs. However most of the mass of the hadrons is not due to the mass of these elementary constituents but to their binding force. Studying the hadron spectrum is therefore a tool to understand one of the fundamental forces in nature, the strong force, and Quantum Chromo Dynamics (QCD), the theory that describes it. This investigation can provide an answer to fundamental questions as what is the origin of the mass of hadrons, what is the origin of quark confinement, what are the relevant degrees of freedom to describe these complex systems and how the transition between the elementary constituents, quarks and gluons, and baryons and mesons occurs. In this field a key tool is given by meson spectroscopy. Mesons, being made by a quark and an anti-quark, are the simplest quark bound system and therefore the ideal benchmark to study the interaction between quarks and understand what the role of gluons is. In this investigation, it is fundamental to precisely determine the spectrum and properties of mesons but also to search for possible unconventional states beyond the qbar q configuration as tetraquarks (qqoverline{qq}), hybrids (qbar qg) and glueballs. These states can be distinguished unambiguously from regular mesons when they have exotic quantum numbers, i.e. combinations of total angular momentum, spin and parity that are not allowed for qbar q states. These are called exotic quantum numbers and the corresponding states are referred to as exotics. The study of the meson spectrum and the search for exotics is among the goals of several experiments in the world that exploit different reaction processes, as e+e- annihilation, pbar p annihilation, pion scattering, proton-proton scattering and photo-production, to produce meson states. This intense effort is

Measurement of the branching fraction $${\\mathcal{B}}(\\Lambda^0_b\\rightarrow \\Lambda^+_c\\pi^-\\pi^+\\pi^-)$$ at CDF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aaltonen, T.; /Helsinki Inst. of Phys.; Alvarez Gonzalez, B.

We report an analysis of the {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -} decay in a data sample collected by the CDF II detector at the Fermilab Tevatron corresponding to 2.4 fb{sup -1} of integrated luminosity. We reconstruct the currently largest samples of the decay modes {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}(2595){sup +}{pi}{sup -} (with {Lambda}{sub c}(2595){sup +} {yields} {Lambda}{sub c}{sup +}{pi}{sup +}{pi}{sup -}), {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}(2625){sup +}{pi}{sup -} (with {Lambda}{sub c}(2625){sup +} {yields} {Lambda}{sub c}{sup +}{pi}{sup +}{pi}{sup -}), {Lambda}{sub b}{sup 0} {yields} {Sigma}{sub c}(2455){sup ++}{pi}{sup -}{pi}{sup -} (with {Sigma}{sub c}(2455){sup ++} {yields} {Lambda}{submore » c}{sup +}{pi}{sup +}), and {Lambda}{sub b}{sup 0} {yields} {Sigma}{sub c}(2455)0{pi}{sup +}{pi}{sup -} (with {Sigma}{sub c}(2455)0 {yields} {Lambda}{sub c}{sup +}{pi}{sup -}) and measure the branching fractions relative to the {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +}{pi}{sup -} branching fraction. We measure the ratio {Beta}({Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -})/ {Beta}({Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +}{pi}{sup -})=3.04 {+-} 0.33(stat){sub -0.55}{sup +0.70}(syst) which is used to derive {Beta}({Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -})=(26.8{sub -11.2}{sup +11.9}) x 10{sup -3}.« less

Leptonic decays of charged D and Ds mesons

NASA Astrophysics Data System (ADS)

Menaa, Nabil

Using 281 pb--1 of data taken on the psi(3770) resonance and 314 pb--1 of data near or at 4170 MeV collected with the CLEO-c detector, we present two analyses to study the purely leptonic decays of charmed and charmed strange charged mesons. In the first analysis, we extract a relatively precise value for the decay constant of the D+ meson by measuring B (D+ → mu+nu) = (4.40 +/- 0.66+0.09-0.12 ) x 10-4. We find fD + = (222.6 +/- 16.7+2.8-3.4 ) MeV, and compare with current theoretical calculations. We also set a 90% confidence upper limit on B (D+ → e +nu) < 2.4 x 10-5 which constrains new physics models. Finally with this data sample, we test whether or not the tau lepton manifests the same couplings as the mu lepton by investigating the relative decay rates in purely leptonic D+ meson decays. We limit B (D+ → tau+nu) < 2.1 x 10--3 at 90% confidence level (C. L.), thus allowing us to place the first upper limit on the ratio R = Gamma (D+ → tau+nu)/Gamma( D+ → mu+nu). The ratio of R to the Standard Model expectation of 2.65 then is <1.8 at 90% C. L., consistent with the prediction of lepton universality. In the second analysis, we examine e+ e-- → D-sD*+s and D-*sD+s interactions at 4170 MeV using the CLEO-c detector in order to measure the decay constant fD+s . We use the D+s → ℓ+nu channel, where the ℓ+ designates either a mu+ or a tau+, when the tau+ → pi+nu. Analyzing both modes independently, we determine B ( D+s → mu+nu) = (0.594 +/- 0.066 +/- 0.031)%, B ( D+s → tau+nu) = (8.0 +/- 1.3 +/- 0.4)%. We also analyze them simultaneously to find an effective value of B ( D+s → mu+nu) = (0.621 +/- 0.058 +/- 0.032)% and extract fD+s = 270 +/- 13 +/- 7 MeV. Combining with our previous determination of B (D+ → mu+nu), we also find the ratio fD+s/fD+ = 1.21 +/- 0.11 +/- 0.04. We compare with current theoretical estimates. Finally, we limit B ( D+s → e+nu) < 1.3 x 10 --4 at 90% confidence level.

Multistrange Meson-Baryon Dynamics and Resonance Generation

NASA Astrophysics Data System (ADS)

Khemchandani, K. P.; Martínez Torres, A.; Hosaka, A.; Nagahiro, H.; Navarra, F. S.; Nielsen, M.

2018-05-01

In this talk I review our recent studies on meson-baryon systems with strangeness - 1 and - 2. The motivation of our works is to find resonances generated as a consequence of coupled channel meson-baryon interactions. The coupled channels are all meson-baryon systems formed by combining a pseudoscalar or a vector meson with an octet baryon such that the system has the strange quantum number equal to - 1 or - 2. The lowest order meson-baryon interaction amplitudes are obtained from Lagrangians based on the chiral and the hidden local symmetries related to the vector mesons working as the gauge bosons. These lowest order amplitudes are used as an input to solve the Bethe-Salpeter equation and a search for poles is made in the resulting amplitudes, in the complex plane. In case of systems with strangeness - 1, we find evidence for the existence of some hyperons such as: Λ(2000), Σ(1750), Σ(1940), Σ(2000). More recently, in the study of strangeness - 2 systems we have found two narrow resonances which can be related to Ξ (1690) and Ξ(2120). In this latter work, we have obtained the lowest order amplitudes relativistically as well as in the nonrelativistic approximation to solve the scattering equations. We find that the existence of the poles in the complex plane does not get affected by the computation of the scattering equation with the lowest order amplitudes obtained in the nonrelativistic approximation.

First observation and measurement of the resonant structure of the lambda_b->lambda_c pi-pi+pi- decay mode

DOE Office of Scientific and Technical Information (OSTI.GOV)

Azzurri, P.; Barria, P.; Ciocci, M.A.

The authors present the first observation of the {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -} decay using data from an integrated luminosity of approximately 2.4 fb{sup -1} of p{bar p} collisions at {radical}s = 1.96 TeV, collected with the CDF II detector at the Fermilab Tevatron. They also present the first observation of the resonant decays {Lambda}{sub b}{sup 0} {yields} {Sigma}{sub c}(2455){sup 0} {pi}{sup +}{pi}{sup -} {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -}, {Lambda}{sub b}{sup 0} {yields} {Sigma}{sub c}(2455){sup ++}{pi}{sup -}{pi}{sup -} {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -}, {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}(2595){sup +}{pi}{sup -}more » {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -} and {Lambda}{sub b}{sup 0} {yields} {Lambda}{sub c}(2625){sup +}{pi}{sup -} {yields} {Lambda}{sub c}{sup +}{pi}{sup -}{pi}{sup +}{pi}{sup -}, and measure their relative branching ratios.« less

Exotic and qq-bar resonances in the pi+pi-pi- system produced in pi-p collisions at 18 GeV/c

DOE Office of Scientific and Technical Information (OSTI.GOV)

S. U. Chung; K. Danyo; R. W. Hackenburg

A partial-wave analysis of the reaction pi{sup -}p-->pi{sup +}pi{sup -}pi{sup -}p at 18 GeV/c has been performed on a data sample of 250 000 events obtained in the Brookhaven experiment E852. The well-known a{sub 1}(1260), a{sub 2}(1320) and pi{sub 2}(1670) resonant states are observed. The existence of the pi(1800), a{sub 1}(1700) and a{sub 4}(2040) states is confirmed. The a{sub 3}(1874) state is also observed. The exotic 1{sup -+} pi{sub 1}(1600) state produced in the natural parity exchange process is found to decay in the rho(770)pi{sup -} channel. A mass-dependent fit results in a resonance mass of 1593{+-}8{sub -47}{sup +29} MeV/c{supmore » 2} and a width of 168{+-}20{sub -12}{sup +150} MeV/c{sup 2}.« less

a Study of Charged d* Mesons Produced in Electron - Annihilation at Center-Of Energy = 29 GEV

NASA Astrophysics Data System (ADS)

Yamamoto, Hitoshi

Charged D* mesons produced in e('+)e('-) annihilation at a center- of-mass energy of 29 GeV have been studied with the DELCO detec- tor at the PEP storage ring. The selection criteria of D* candidates exploit the (pi)/K separation capability in the momentum range from 2.6 GeV/c to 9.2 GeV/c provided by the gas Cerenkov counter. The data correspond to an integrated luminosity of 147 pb(' -1). We have measured the total production cross section of D*('(+OR-)) to be 0.16 (+OR-) 0.02(statistical) (+OR -) 0.02(systematic) nb x (TBOND) P(,D*)/(E(,beam)('2) - M(,D*)('2))(' 1/2) > 0.35 , and (0.18 (+OR-) 0.02 (+OR -) 0.03) nb (x > 0) if the contribution from bottom quarks is subtracted. The branching fractions used are Br(D*('+) (--->) D('0)(pi)('+)) = 64% and Br(D('0) (--->) K('-)(pi)('+)) = 3%. The systematic errors due to the branching ratios are not included in the errors. With Br(D('0) (--->) K(' -)(pi)('+)) = 4.9%, which is a recent measurement by the MARK III group, the above two cross sections become 0.10 (+OR-) 0.02 (+OR-) 0.02 nb (x > 0.35) and 0.11 (+OR-) 0.02 (+OR-) 0.02 nb (x > 0 and after the sub- traction of the contribution from b quarks). The charm fragmentation function is harder than that for light quarks, and the shape is found to be consistent with the prediction of the string model with a uniform string-breaking probability. Assuming the string model, the string-breaking probability is determined to be (0.019 (+OR-) 0.05 (+OR-) 0.09) GeV/c('2). We have also determined the lifetime of D('0) meson which is detec- ted in the D* decay, with the result. (DIAGRAM, TABLE OR GRAPHIC OMITTED...PLEASE SEE DAI). Together with the semileptonic branching fraction of D('0) measured elsewhere, the semileptonic decay rate of D('0) is estimated to be (1.4 (+OR-) 0.5) x 10('11) sec('-1), which corresponds to an effective charm quark mass of (1.54 (+OR-) 0.12) GeV/c('2). Using part of the D* candidates, we have set an upper limit on D('0)-(')D('0) mixing: r (TBOND) P

Hypernuclear Weak Decays

NASA Astrophysics Data System (ADS)

Itonaga, K.; Motoba, T.

The recent theoretical studies of Lambda-hypernuclear weak decaysof the nonmesonic and pi-mesonic ones are developed with the aim to disclose the link between the experimental decay observables and the underlying basic weak decay interactions and the weak decay mechanisms. The expressions of the nonmesonic decay rates Gamma_{nm} and the decay asymmetry parameter alpha_1 of protons from the polarized hypernuclei are presented in the shell model framework. We then introduce the meson theoretical Lambda N -> NN interactions which include the one-meson exchanges, the correlated-2pi exchanges, and the chiral-pair-meson exchanges. The features of meson exchange potentials and their roles on the nonmesonic decays are discussed. With the adoption of the pi + 2pi/rho + 2pi/sigma + omega + K + rhopi/a_1 + sigmapi/a_1 exchange potentials, we have carried out the systematic calculations of the nonmesonic decay observables for light-to-heavy hypernuclei. The present model can account for the available experimental data of the decay rates, Gamma_n/Gamma_p ratios, and the intrinsic asymmetry parameters alpha_Lambda (alpha_Lambda is related to alpha_1) of emitted protons well and consistently within the error bars. The hypernuclear lifetimes are evaluated by converting the total weak decay rates Gamma_{tot} = Gamma_pi + Gamma_{nm} to tau, which exhibit saturation property for the hypernuclear mass A ≥ 30 and agree grossly well with experimental data for the mass range from light to heavy hypernuclei except for the very light ones. Future extensions of the model and the remaining problems are also mentioned. The pi-mesonic weak processes are briefly surveyed, and the calculations and predictions are compared and confirmed by the recent high precision FINUDA pi-mesonic decay data. This shows that the theoretical basis seems to be firmly grounded.

Coupling constant for N*(1535)N{rho}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Xie Jujun; Graduate University of Chinese Academy of Sciences, Beijing 100049; Wilkin, Colin

2008-05-15

The value of the N*(1535)N{rho} coupling constant g{sub N*N{rho}} derived from the N*(1535){yields}N{rho}{yields}N{pi}{pi} decay is compared with that deduced from the radiative decay N*(1535){yields}N{gamma} using the vector-meson-dominance model. On the basis of an effective Lagrangian approach, we show that the values of g{sub N*N{rho}} extracted from the available experimental data on the two decays are consistent, though the error bars are rather large.

Improved perturbative QCD formalism for Bc meson decays

NASA Astrophysics Data System (ADS)

Liu, Xin; Li, Hsiang-nan; Xiao, Zhen-Jun

2018-06-01

We derive the kT resummation for doubly heavy-flavored Bc meson decays by including the charm quark mass effect into the known formula for a heavy-light system. The resultant Sudakov factor is employed in the perutrbative QCD study of the "golden channel" Bc+→J /ψ π+. With a reasonable model for the Bc meson distribution amplitude, which maintains approximate on-shell conditions of both the partonic bottom and charm quarks, it is observed that the imaginary piece of the Bc→J /ψ transition form factor appears to be power suppressed, and the Bc+→J /ψ π+ branching ratio is not lower than 10-3. The above improved perturbative QCD formalism is applicable to Bc meson decays to other charmonia and charmed mesons.

Measurement of direct f0(980) photoproduction on the proton.

PubMed

Battaglieri, M; De Vita, R; Szczepaniak, A P; Adhikari, K P; Aghasyan, M; Amaryan, M J; Ambrozewicz, P; Anghinolfi, M; Asryan, G; Avakian, H; Bagdasaryan, H; Baillie, N; Ball, J P; Baltzell, N A; Batourine, V; Bedlinskiy, I; Bellis, M; Benmouna, N; Berman, B L; Bibrzycki, L; Biselli, A S; Bookwalter, C; Bouchigny, S; Boiarinov, S; Bradford, R; Branford, D; Briscoe, W J; Brooks, W K; Bültmann, S; Burkert, V D; Calarco, J R; Careccia, S L; Carman, D S; Casey, L; Chen, S; Cheng, L; Clinton, E; Cole, P L; Collins, P; Crabb, D; Crannell, H; Crede, V; Cummings, J P; Dale, D; Daniel, A; Dashyan, N; De Masi, R; De Sanctis, E; Degtyarenko, P V; Deur, A; Dhamija, S; Dharmawardane, K V; Dickson, R; Djalali, C; Dodge, G E; Donnelly, J; Doughty, D; Dugger, M; Dzyubak, O P; Egiyan, H; Egiyan, K S; El Fassi, L; Elouadrhiri, L; Eugenio, P; Fedotov, G; Fersch, R; Forest, T A; Fradi, A; Gabrielyan, M Y; Gan, L; Garçon, M; Gasparian, A; Gavalian, G; Gevorgyan, N; Gilfoyle, G P; Giovanetti, K L; Girod, F X; Glamazdin, O; Goett, J; Goetz, J T; Gohn, W; Golovatch, E; Gordon, C I O; Gothe, R W; Graham, L; Griffioen, K A; Guidal, M; Guler, N; Guo, L; Gyurjyan, V; Hadjidakis, C; Hafidi, K; Hakobyan, H; Hakobyan, R S; Hanretty, C; Hardie, J; Hassall, N; Heddle, D; Hersman, F W; Hicks, K; Hleiqawi, I; Holtrop, M; Hyde, C E; Ilieva, Y; Ireland, D G; Ishkhanov, B S; Isupov, E L; Ito, M M; Jenkins, D; Jo, H S; Johnstone, J R; Joo, K; Juengst, H G; Kageya, T; Kalantarians, N; Keller, D; Kellie, J D; Khandaker, M; Khetarpal, P; Kim, W; Klein, A; Klein, F J; Klimenko, A V; Konczykowski, P; Kossov, M; Krahn, Z; Kramer, L H; Kubarovsky, V; Kuhn, J; Kuhn, S E; Kuleshov, S V; Kuznetsov, V; Lachniet, J; Laget, J M; Langheinrich, J; Lawrence, D; Lee, T; Lesniak, L; Li, Ji; Livingston, K; Lowry, M; Lu, H Y; Maccormick, M; Malace, S; Markov, N; Mattione, P; McCracken, M E; McKinnon, B; Mecking, B A; Melone, J J; Mestayer, M D; Meyer, C A; Mibe, T; Mikhailov, K; Mineeva, T; Minehart, R; Mirazita, M; Miskimen, R; Mochalov, V; Mokeev, V; Moreno, B; Moriya, K; Morrow, S A; Moteabbed, M; Munevar, E; Mutchler, G S; Nadel-Turonski, P; Nakagawa, I; Nasseripour, R; Niccolai, S; Niculescu, G; Niculescu, I; Niczyporuk, B B; Niroula, M R; Niyazov, R A; Nozar, M; Osipenko, M; Ostrovidov, A I; Park, K; Park, S; Pasyuk, E; Paris, M; Paterson, C; Pereira, S Anefalos; Pierce, J; Pivnyuk, N; Pocanic, D; Pogorelko, O; Pozdniakov, S; Price, J W; Prok, Y; Protopopescu, D; Raue, B A; Riccardi, G; Ricco, G; Ripani, M; Ritchie, B G; Rosner, G; Rossi, P; Sabatié, F; Saini, M S; Salamanca, J; Salgado, C; Sandorfi, A; Santoro, J P; Sapunenko, V; Schott, D; Schumacher, R A; Serov, V S; Sharabian, Y G; Sharov, D; Shvedunov, N V; Smith, E S; Smith, L C; Sober, D I; Sokhan, D; Starostin, A; Stavinsky, A; Stepanyan, S; Stepanyan, S S; Stokes, B E; Stoler, P; Stopani, K A; Strakovsky, I I; Strauch, S; Taiuti, M; Tedeschi, D J; Teymurazyan, A; Tkabladze, A; Tkachenko, S; Todor, L; Tur, C; Ungaro, M; Vineyard, M F; Vlassov, A V; Watts, D P; Wei, X; Weinstein, L B; Weygand, D P; Williams, M; Wolin, E; Wood, M H; Yegneswaran, A; Yurov, M; Zana, L; Zhang, J; Zhao, B; Zhao, Z W

2009-03-13

We report on the results of the first measurement of exclusive f_{0}(980) meson photoproduction on protons for E_{gamma}=3.0-3.8 GeV and -t=0.4-1.0 GeV2. Data were collected with the CLAS detector at the Thomas Jefferson National Accelerator Facility. The resonance was detected via its decay in the pi;{+}pi;{-} channel by performing a partial wave analysis of the reaction gammap-->ppi;{+}pi;{-}. Clear evidence of the f_{0}(980) meson was found in the interference between P and S waves at M_{pi;{+}pi;{-}} approximately 1 GeV. The S-wave differential cross section integrated in the mass range of the f_{0}(980) was found to be a factor of about 50 smaller than the cross section for the rho meson. This is the first time the f_{0}(980) meson has been measured in a photoproduction experiment.

Couplings between the ρ and D and D * mesons

DOE PAGES

El-Bennich, Bruno; Paracha, M. Ali; Roberts, Craig D.; ...

2017-02-27

In this paper, we compute couplings between the ρ-meson and D and D* mesons—D(*)ρD(*)—that are relevant to phenomenological meson-exchange models used to analyze nucleon–D-meson scattering and explore the possibility of exotic charmed nuclei. Our framework is built from elements constrained by Dyson-Schwinger equation studies in QCD, and therefore expresses a simultaneous description of light- and heavy-quarks and the states they constitute. We find that all interactions, including the three independent D*ρD* couplings, differ markedly amongst themselves in strength and also in range, as measured by their evolution with ρ-meson virtuality. As a consequence, it appears that one should be cautiousmore » in using a single coupling strength or parametrization for the study of interactions between D(*) mesons and matter.« less

Couplings between the ρ and D and D * mesons

DOE Office of Scientific and Technical Information (OSTI.GOV)

El-Bennich, Bruno; Paracha, M. Ali; Roberts, Craig D.

In this paper, we compute couplings between the ρ-meson and D and D* mesons—D(*)ρD(*)—that are relevant to phenomenological meson-exchange models used to analyze nucleon–D-meson scattering and explore the possibility of exotic charmed nuclei. Our framework is built from elements constrained by Dyson-Schwinger equation studies in QCD, and therefore expresses a simultaneous description of light- and heavy-quarks and the states they constitute. We find that all interactions, including the three independent D*ρD* couplings, differ markedly amongst themselves in strength and also in range, as measured by their evolution with ρ-meson virtuality. As a consequence, it appears that one should be cautiousmore » in using a single coupling strength or parametrization for the study of interactions between D(*) mesons and matter.« less

New predictions on meson decays from string splitting

NASA Astrophysics Data System (ADS)

Bigazzi, Francesco; Cotrone, Aldo L.

2006-11-01

We study certain exclusive decays of high spin mesons into mesons in models of large Nc Yang-Mills with few flavors at strong coupling using string theory. The rate of the process is calculated by studying the splitting of a macroscopic string on the relevant dual gravity backgrounds. In the leading channel for the decay of heavy quarkonium into two open-heavy quark states, one of the two produced mesons has much larger spin than the other. In this channel the decay rate is practically independent on the spin and has a mild dependence on the mass of the heavy quarks. Moreover, it is only power-like suppressed with the mass of the produced quark-anti quark pair. We also reconsider decays of high spin mesons made up of light quarks, confirming the linear dependence of the rate on the mass of the decaying meson. As a bonus of our computation, we provide a formula for the splitting rate of a macroscopic string lying on a Dp-brane in flat space.

Chiral symmetry and N*(1440){yields}N{pi}{pi} decay

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kamano, H.; Morishita, M.; Arima, M.

2005-04-01

The N*(1440){yields}N{pi}{pi} decay is studied by making use of the chiral reduction formula. This formula suggests a scalar-isoscalar pion-baryon contact interaction that is absent in the recent study of Hernandez et al. [Phys. Rev. C 66, 065201 (2002)]. The contact interaction is introduced into their model and is found to be necessary for the simultaneous description of g{sub RN{pi}}{sub {pi}} and the {pi}{pi} and {pi}N invariant mass distributions.

Near-threshold J/ψ-meson photoproduction on nuclei

DOE Office of Scientific and Technical Information (OSTI.GOV)

Paryev, E. Ya.; Kiselev, Yu. T., E-mail: yurikis@itep.ru

On the basis of the first-collision model that relies on the nuclear spectral function and which includes incoherent processes involving charmonium production in proton–nucleon collisions, the photoproduction of J/ψ mesons on nuclei is considered at energies close to the threshold for their production on a nucleon. The absorption of final J/ψ mesons, their formation length, and the binding and Fermi motion of target nucleons are taken into account in this model along with the effect of the nuclear potential on these processes. The A dependences of the absolute and relative charmonium yields are calculated together with absolute and relative excitationmore » functions under various assumptions on the magnitude of the cross section for J/ψN absorption, the J/ψ-meson formation length, and their inmedium modification. It is shown that, at energies above the threshold, these features are virtually independent of the formation length and the change in the J/ψ-meson mass in nuclear matter but are rather highly sensitive to the cross section for J/ψN interaction. The calculations performed in the present study can be used to determine the unknown cross section for J/ψ-meson absorption in nuclei from a comparison of their results with data expected from experiments in the Hall C of the CEBAF (USA) facility upgraded to the energy of 12 GeV. It is also shown that the absolute and relative excitation functions for J/ψ mesons in photon–nucleus reactions at subthreshold energies are sensitive to the change in the meson mass and, hence, carry information about the properties of charmonium in nuclear matter.« less

Study of light mesons with WASA-at-COSY

NASA Astrophysics Data System (ADS)

Prencipe, Elisabetta

2014-06-01

The WASA detector, operating at the COSY facility in Jülich (Germany) has been collecting data since 2007. The experiment allows to perform studies of light mesons, such as π0, η and ω rare decay processes, in order to perform precise measurements of branching ratios, determine Dalitz plot parameters, test symmetry and symmetry breaking, and evaluate transition form factors. In the experiments a proton or deuteron beam impinged on a pellet target of hydrogen or deuterium, which allows the reactions proton-proton (pp) or proton-deuteron (pd). A high-statistics sample of η mesons has been collected: in the reaction pd →3He η, 3×107η mesons were tagged at a beam energy of 1.0 GeV, while 5×108η mesons were produced in the reaction pp → ppη at 1.4 GeV. This corresponds to the production of 10 η/s and 100 η/s, respectively, for the two reaction processes. In the pp dataset a higher background level is found compared to the pd data set. In both cases, we identify the η mesons by means of the missing mass derived from the recoil particles. A kinematic fit largely rejects the background in our analysis. The advantage in using the pp dataset is that the production of η mesons is almost a factor of 10 higher than in the pd fusion to 3He. As we plan to measure the branching ratios of very rare processes, high statistics is needed. A summary of the recent activity on the study of light mesons with WASA-at-COSY here is given.

Measurement of the beam asymmetry Σ and the target asymmetry T in the photoproduction of ω mesons off the proton using CLAS at Jefferson Laboratory

DOE PAGES

Roy, P.; Akbar, Z.; Park, S.; ...

2018-05-04

Here, the photoproduction ofmore » $$\\omega$$ mesons off the proton has been studied in the reaction $$\\gamma p\\to p\\,\\omega$$ using the CEBAF Large Acceptance Spectrometer (CLAS) and the frozen-spin target (FROST) in Hall B at the Thomas Jefferson National Accelerator Facility. For the first time, the target asymmetry, $T$, has been measured in photoproduction from the decay $$\\omega\\to\\pi^+\\pi^-\\pi^0$$, using a transversely-polarized target with energies ranging from just above the reaction threshold up to 2.8 GeV. Significant non-zero values are observed for these asymmetries, reaching about 30-40% in the third-resonance region. New measurements for the photon-beam asymmetry, $$\\Sigma$$, are also presented, which agree well with previous CLAS results and extend the world database up to 2.1 GeV. These data and additional $$\\omega$$-photoproduction observables from CLAS were included in a partial-wave analysis within the Bonn-Gatchina framework. Significant contributions from $s$-channel resonance production were found in addition to $t$-channel exchange processes.« less

Measurement of the beam asymmetry Σ and the target asymmetry T in the photoproduction of ω mesons off the proton using CLAS at Jefferson Laboratory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Roy, P.; Akbar, Z.; Park, S.

Here, the photoproduction ofmore » $$\\omega$$ mesons off the proton has been studied in the reaction $$\\gamma p\\to p\\,\\omega$$ using the CEBAF Large Acceptance Spectrometer (CLAS) and the frozen-spin target (FROST) in Hall B at the Thomas Jefferson National Accelerator Facility. For the first time, the target asymmetry, $T$, has been measured in photoproduction from the decay $$\\omega\\to\\pi^+\\pi^-\\pi^0$$, using a transversely-polarized target with energies ranging from just above the reaction threshold up to 2.8 GeV. Significant non-zero values are observed for these asymmetries, reaching about 30-40% in the third-resonance region. New measurements for the photon-beam asymmetry, $$\\Sigma$$, are also presented, which agree well with previous CLAS results and extend the world database up to 2.1 GeV. These data and additional $$\\omega$$-photoproduction observables from CLAS were included in a partial-wave analysis within the Bonn-Gatchina framework. Significant contributions from $s$-channel resonance production were found in addition to $t$-channel exchange processes.« less

Observation of pi{sup +}pi{sup -}pi{sup +}pi{sup -} photoproduction in ultraperipheral heavy-ion collisions at sq root(s{sub NN})=200 GeV at the STAR detector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Abelev, B. I.; Betts, R. R.; Evdokimov, O.

We present a measurement of pi{sup +}pi{sup -}pi{sup +}pi{sup -} photonuclear production in ultraperipheral Au-Au collisions at sq root(s{sub N{sub N}})=200 GeV from the STAR experiment. The pi{sup +}pi{sup -}pi{sup +}pi{sup -} final states are observed at low transverse momentum and are accompanied by mutual nuclear excitation of the beam particles. The strong enhancement of the production cross section at low transverse momentum is consistent with coherent photoproduction. The pi{sup +}pi{sup -}pi{sup +}pi{sup -} invariant mass spectrum of the coherent events exhibits a broad peak around 1540+-40 MeV/c{sup 2} with a width of 570+-60 MeV/c{sup 2}, in agreement with themore » photoproduction data for the rho{sup 0}(1700). We do not observe a corresponding peak in the pi{sup +}pi{sup -} final state and measure an upper limit for the ratio of the branching fractions of the rho{sup 0}(1700) to pi{sup +}pi{sup -} and pi{sup +}pi{sup -}pi{sup +}pi{sup -} of 2.5% at 90% confidence level. The ratio of rho{sup 0}(1700) and rho{sup 0}(770) coherent production cross sections is measured to be 13.4+-0.8{sub stat.}+-4.4{sub syst.}%.« less

Physics objectives of PI3 spherical tokamak program

NASA Astrophysics Data System (ADS)

Howard, Stephen; Laberge, Michel; Reynolds, Meritt; O'Shea, Peter; Ivanov, Russ; Young, William; Carle, Patrick; Froese, Aaron; Epp, Kelly

2017-10-01

Achieving net energy gain with a Magnetized Target Fusion (MTF) system requires the initial plasma state to satisfy a set of performance goals, such as particle inventory (1021 ions), sufficient magnetic flux (0.3 Wb) to confine the plasma without MHD instability, and initial energy confinement time several times longer than the compression time. General Fusion (GF) is now constructing Plasma Injector 3 (PI3) to explore the physics of reactor-scale plasmas. Energy considerations lead us to design around an initial state of Rvessel = 1 m. PI3 will use fast coaxial helicity injection via a Marshall gun to create a spherical tokamak plasma, with no additional heating. MTF requires solenoid-free startup with no vertical field coils, and will rely on flux conservation by a metal wall. PI3 is 5x larger than SPECTOR so is expected to yield magnetic lifetime increase of 25x, while peak temperature of PI3 is expected to be similar (400-500 eV) Physics investigations will study MHD activity and the resistive and convective evolution of current, temperature and density profiles. We seek to understand the confinement physics, radiative loss, thermal and particle transport, recycling and edge physics of PI3.

The role of meson exchanges in light-by-light scattering

NASA Astrophysics Data System (ADS)

Lebiedowicz, Piotr; Szczurek, Antoni

2017-09-01

We discuss the role of meson exchange mechanisms in γγ → γγ scattering. Several pseudoscalar (π0, η, η‧ (958), ηc (1 S), ηc (2 S)), scalar (f0 (500), f0 (980), a0 (980), f0 (1370), χc0 (1 P)) and tensor (f2 (1270), a2 (1320), f2‧ (1525), f2 (1565), a2 (1700)) mesons are taken into account. We consider not only s-channel but also for the first time t- and u-channel meson exchange amplitudes corrected for off-shell effects including vertex form factors. We find that, depending on not well known vertex form factors, the meson exchange amplitudes interfere among themselves and could interfere with fermion-box amplitudes and modify the resulting cross sections. The meson contributions are shown as a function of collision energy as well as angular distributions are presented. Interesting interference effects separately for light pseudoscalar, scalar and tensor meson groups are discussed. The meson exchange contributions may be potentially important in the context of a measurement performed recently in ultraperipheral collisions of heavy ions by the ATLAS collaboration. The light-by-light interactions could be studied in future in electron-positron collisions by the Belle II at SuperKEKB accelerator.

Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing

PubMed Central

Le Thomas, Adrien; Stuwe, Evelyn; Li, Sisi; Marinov, Georgi; Rozhkov, Nikolay; Chen, Yung-Chia Ariel; Luo, Yicheng; Sachidanandam, Ravi; Toth, Katalin Fejes; Patel, Dinshaw; Aravin, Alexei A.

2014-01-01

Small noncoding RNAs that associate with Piwi proteins, called piRNAs, serve as guides for repression of diverse transposable elements in germ cells of metazoa. In Drosophila, the genomic regions that give rise to piRNAs, the so-called piRNA clusters, are transcribed to generate long precursor molecules that are processed into mature piRNAs. How genomic regions that give rise to piRNA precursor transcripts are differentiated from the rest of the genome and how these transcripts are specifically channeled into the piRNA biogenesis pathway are not known. We found that transgenerationally inherited piRNAs provide the critical trigger for piRNA production from homologous genomic regions in the next generation by two different mechanisms. First, inherited piRNAs enhance processing of homologous transcripts into mature piRNAs by initiating the ping-pong cycle in the cytoplasm. Second, inherited piRNAs induce installment of the histone 3 Lys9 trimethylation (H3K9me3) mark on genomic piRNA cluster sequences. The heterochromatin protein 1 (HP1) homolog Rhino binds to the H3K9me3 mark through its chromodomain and is enriched over piRNA clusters. Rhino recruits the piRNA biogenesis factor Cutoff to piRNA clusters and is required for efficient transcription of piRNA precursors. We propose that transgenerationally inherited piRNAs act as an epigenetic memory for identification of substrates for piRNA biogenesis on two levels: by inducing a permissive chromatin environment for piRNA precursor synthesis and by enhancing processing of these precursors. PMID:25085419

Functional analysis reveals the possible role of the C-terminal sequences and PI motif in the function of lily (Lilium longiflorum) PISTILLATA (PI) orthologues

PubMed Central

Chen, Ming-Kun; Hsieh, Wen-Ping; Yang, Chang-Hsien

2012-01-01

Two lily (Lilium longiflorum) PISTILLATA (PI) genes, Lily MADS Box Gene 8 and 9 (LMADS8/9), were characterized. LMADS9 lacked 29 C-terminal amino acids including the PI motif that was present in LMADS8. Both LMADS8/9 mRNAs were prevalent in the first and second whorl tepals during all stages of development and were expressed in the stamen only in young flower buds. LMADS8/9 could both form homodimers, but the ability of LMADS8 homodimers to bind to CArG1 was relatively stronger than that of LMADS9 homodimers. 35S:LMADS8 completely, and 35S:LMADS9 only partially, rescued the second whorl petal formation and partially converted the first whorl sepal into a petal-like structure in Arabidopsis pi-1 mutants. Ectopic expression of LMADS8-C (with deletion of the 29 amino acids of the C-terminal sequence) or LMADS8-PI (with only the PI motif deleted) only partially rescued petal formation in pi mutants, which was similar to what was observed in 35S:LMADS9/pi plants. In contrast, 35:LMADS9+L8C (with the addition of the 29 amino acids of the LMADS8 C-terminal sequence) or 35S:LMADS9+L8PI (with the addition of the LMADS8 PI motif) demonstrated an increased ability to rescue petal formation in pi mutants, which was similar to what was observed in 35S:LMADS8/pi plants. Furthermore, ectopic expression of LMADS8-M (with the MADS domain truncated) generated more severe dominant negative phenotypes than those seen in 35S:LMADS9-M flowers. These results revealed that the 29 amino acids including the PI motif in the C-terminal region of the lily PI orthologue are valuable for its function in regulating perianth organ formation. PMID:22068145

Radiative resonance couplings in γ π →π π

NASA Astrophysics Data System (ADS)

Hoferichter, Martin; Kubis, Bastian; Zanke, Marvin

2017-12-01

Studies of the reaction γ π →π π , in the context of the ongoing Primakoff program of the COMPASS experiment at CERN, give access to the radiative couplings of the ρ (770 ) and ρ3(1690 ) resonances. We provide a vector-meson-dominance estimate of the respective radiative width of the ρ3, Γρ3→πγ=48 (18 ) keV , as well as its impact on the F -wave in γ π →π π . For the ρ (770 ), we establish the formalism necessary to extract its radiative coupling directly from the residue of the resonance pole by analytic continuation of the γ π →π π amplitude to the second Riemann sheet, without any reference to the vector-meson-dominance hypothesis.

The mechanism of the effect of a plasma layer with negative permittivity on the antenna radiation field

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Chunsheng, E-mail: wangcs@hit.edu.cn; Liu, Hui; Jiang, Binhao

A model of a plasma–antenna system is developed to study the mechanism of the effect of the plasma layer on antenna radiation. Results show a plasma layer with negative permittivity is inductive, and thus affects the phase difference between electric and magnetic fields. In the near field of antenna radiation, a plasma layer with proper parameters can compensate the capacitivity of the vacuum and enhance the radiation power. In the far field of antenna radiation, the plasma layer with negative permittivity increases the inductivity of the vacuum and reduces the radiation power.

Single Meson Photoproduction at JLab Energies

NASA Astrophysics Data System (ADS)

Mathieu, Vincent; Joint Physics Analysis Center Team

2016-09-01

In this talk, I present the results from the Joint Physics Analysis Center about the photoproduction of a single meson (pseudoscalar or vector meson). We have developed the theoretical formalism to analysis forthcoming data at the, recently upgraded, JLab facility. We also present prediction for observables in the energy range of Eg = 5-11 GeV. Material (codes, notes, sim- ulations, etc) can be found online at the JPAC interactive website: http://www.indiana.edu/ jpac/index.html

Measurement of CP-Violating Asymmetries in B0 to (rho pi)0 Using a Time-Dependent Dalitz Plot Analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wu, J.

We present the preliminary measurement of CP-violating asymmetries in B{sup 0} {yields} ({rho}{pi}){sup 0} {yields} {pi}{sup +}{pi}{sup -}{pi}{sup 0} decays using a time-dependent Dalitz plot analysis. The results are obtained from a data sample of 213 million {Upsilon}(4S) {yields} B{bar B} decays, collected by the BABAR detector at the PEP-II asymmetric-energy B Factory at SLAC. This analysis extends the narrow-rho quasi-two-body approximation used in the previous analysis, by taking into account the interference between the rho resonances of the three charges. We measure 16 coefficients of the bilinear form factor terms occurring in the time-dependent decay rate of the B{supmore » 0} meson with the use of a maximum-likelihood fit. We derive the physically relevant quantities from these coefficients. We measure the direct CP-violation parameters A{sub {rho}{pi}} = -0.088 {+-} 0.049 {+-} 0.013 and C = 0.34 {+-} 0.11 {+-} 0.05, where the first errors are statistical and the second systematic. For the mixing-induced CP-violation parameter we find S = -0.10 {+-} 0.14 {+-} 0.04, and for the dilution and strong phase shift parameters respectively, we obtain {Delta}C = 0.15 {+-} 0.11 {+-} 0.03 and {Delta}S = 0.22 {+-} 0.15 {+-} 0.03. For the angle alpha of the Unitarity Triangle we measure (113{sub -17}{sup +27} {+-} 6){sup o}, while only a weak constraint is achieved at the significance level of more than two standard deviations. Finally, for the relative strong phase {delta}{sub {+-}} between the B{sup 0} {yields} {rho}{sup -}{pi}{sup +} and B{sup 0} {yields} {rho}{sup +}{pi}{sup -} transitions we find (-67{sub -31}{sup +28} {+-} 7) deg, with a similarly weak constraint at two standard deviations and beyond.« less

Relations between heavy-light meson and quark masses

NASA Astrophysics Data System (ADS)

Brambilla, N.; Komijani, J.; Kronfeld, A. S.; Vairo, A.; Tumqcd Collaboration

2018-02-01

The study of heavy-light meson masses should provide a way to determine renormalized quark masses and other properties of heavy-light mesons. In the context of lattice QCD, for example, it is possible to calculate hadronic quantities for arbitrary values of the quark masses. In this paper, we address two aspects relating heavy-light meson masses to the quark masses. First, we introduce a definition of the renormalized quark mass that is free of both scale dependence and renormalon ambiguities, and discuss its relation to more familiar definitions of the quark mass. We then show how this definition enters a merger of the descriptions of heavy-light masses in heavy-quark effective theory and in chiral perturbation theory (χ PT ). For practical implementations of this merger, we extend the one-loop χ PT corrections to lattice gauge theory with heavy-light mesons composed of staggered fermions for both quarks. Putting everything together, we obtain a practical formula to describe all-staggered heavy-light meson masses in terms of quark masses as well as some lattice artifacts related to staggered fermions. In a companion paper, we use this function to analyze lattice-QCD data and extract quark masses and some matrix elements defined in heavy-quark effective theory.

Relations between heavy-light meson and quark masses

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brambilla, N.; Komijani, J.; Kronfeld, A. S.

Here, the study of heavy-light meson masses should provide a way to determine renormalized quark masses and other properties of heavy-light mesons. In the context of lattice QCD, for example, it is possible to calculate hadronic quantities for arbitrary values of the quark masses. In this paper, we address two aspects relating heavy-light meson masses to the quark masses. First, we introduce a definition of the renormalized quark mass that is free of both scale dependence and renormalon ambiguities, and discuss its relation to more familiar definitions of the quark mass. We then show how this definition enters a mergermore » of the descriptions of heavy-light masses in heavy-quark effective theory and in chiral perturbation theory (χPT). For practical implementations of this merger, we extend the one-loop χPT corrections to lattice gauge theory with heavy-light mesons composed of staggered fermions for both quarks. Putting everything together, we obtain a practical formula to describe all-staggered heavy-light meson masses in terms of quark masses as well as some lattice artifacts related to staggered fermions. In a companion paper, we use this function to analyze lattice-QCD data and extract quark masses and some matrix elements defined in heavy-quark effective theory.« less

Relations between heavy-light meson and quark masses

DOE PAGES

Brambilla, N.; Komijani, J.; Kronfeld, A. S.; ...

2018-02-07

Here, the study of heavy-light meson masses should provide a way to determine renormalized quark masses and other properties of heavy-light mesons. In the context of lattice QCD, for example, it is possible to calculate hadronic quantities for arbitrary values of the quark masses. In this paper, we address two aspects relating heavy-light meson masses to the quark masses. First, we introduce a definition of the renormalized quark mass that is free of both scale dependence and renormalon ambiguities, and discuss its relation to more familiar definitions of the quark mass. We then show how this definition enters a mergermore » of the descriptions of heavy-light masses in heavy-quark effective theory and in chiral perturbation theory (χPT). For practical implementations of this merger, we extend the one-loop χPT corrections to lattice gauge theory with heavy-light mesons composed of staggered fermions for both quarks. Putting everything together, we obtain a practical formula to describe all-staggered heavy-light meson masses in terms of quark masses as well as some lattice artifacts related to staggered fermions. In a companion paper, we use this function to analyze lattice-QCD data and extract quark masses and some matrix elements defined in heavy-quark effective theory.« less

Negative radiation forces on spheres illuminated by acoustic Bessel beams.

NASA Astrophysics Data System (ADS)

Marston, Philip L.; Thiessen, David B.

2007-11-01

An analytical solution for the scattering of an acoustic Bessel beam by a sphere centered on the beam has made it possible to explore the way the acoustic radiation force on elastic and fluid spheres depends on beam and material parameters. Situations have been previously noted where, even in the absence of absorption, the radiation force of the beam on the sphere is opposite the direction of beam propagation [1]. In extensions of that work, conditions have been identified for such a force reversal on solid spheres and elastic shells. Negative radiation forces may be useful for manipulation of objects in reduced gravity and of biological cells (with single beam acoustic tweezers). The finite element method (FEM) has been used to evaluate the total acoustic field in the region near the sphere. This makes it possible to evaluate the radiation force from numerical integration of an appropriate projection of the Brillouin radiation stress tensor. FEM and analytical results agree for plane wave and Bessel beam illumination. 1. P. L. Marston, J. Acoust. Soc. Am. 120, 3518-3524 (2006).

ϕ Meson Measurements at RHIC with the PHENIX Detector

NASA Astrophysics Data System (ADS)

Sarsour, Murad

2018-02-01

The measurement of ϕ mesons provides key information on the phase of the hot and dense medium created in the relativistic heavy ion collisions. It has a relatively small hadronic interaction cross section and is sensitive to the increase of strangeness (strangeness enhancement), a phenomenon associated with soft particles in bulk matter. Measurements in the dilepton channels are especially interesting since leptons interact only electromagnetically, thus carrying the information from their production phase directly to the detector. Measurements in different nucleus-nucleus collisions allow us to perform a systematic study of the nuclear medium effects on ϕ meson production. The PHENIX detector provides the capabilities to measure the ϕ meson production in a wide range of transverse momentum and rapidity to study these effects. In this proceeding, we present measurements of the ϕ mesons in a variety of collision systems at = 200 GeV. In case of small systems, the data are compared with AMPT calculations to study the various cold nuclear medium effects involved in ϕ meson production.

Radiation environment simulations at the Tevatron, studies of the beam profile and measurement of the B c meson mass

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nicolas, Ludovic Y.

2005-09-01

The description of a computer simulation of the CDF detector at Fermilab and the adjacent accelerator parts is detailed, with MARS calculations of the radiation background in various elements of the model due to the collision of beams and machine-related losses. Three components of beam halo formation are simulated for the determination of the principal source of radiation background in CDF due to beam losses. The effect of a collimator as a protection for the detector is studied. The simulation results are compared with data taken by a CDF group. Studies of a 150 GeV Tevatron proton beam are performedmore » to investigate the transverse diffusion growth and distribution. A technique of collimator scan is used to scrape the beam under various experimental conditions, and computer programs are written for the beam reconstruction. An average beam halo growth speed is given and the potential of beam tail reconstruction using the collimator scan is evaluated. A particle physics analysis is conducted in order to detect the B c → J/Ψπ decay signal with the CDF Run II detector in 360 pb -1 of data. The cut variables and an optimization method to determine their values are presented along with a criterion for the detection threshold of the signal. The mass of the B{sub c} meson is measured with an evaluation of the significance of the signal.« less

Photoproduction of Mesons

NASA Astrophysics Data System (ADS)

Schmieden, Hartmut; Klein, Friedrich

2017-01-01

B.1 is one of the experimental projects within the CRC16. It aims at the systematic investigation of the photoproduction of mesons off nucleons in order to understand reaction mechanisms and the relevant degrees of freedom in resonance formation. Of particular interest is the photoproduction of mesons heavier than the pion and resonances involving hidden or open strangeness. Essential hardware contributions have been made to the experimental programme of the CRC16 through tagging systems, and photon-beam polarisation and polarimetry. A new experiment has been set up within the framework of the BGO-OD collaboration. This combines a forward magnetic spectrometer with a central BGO calorimeter with charged particle recognition and identification. The BGO-OD experiment enables reconstruction of complex final states composed of both charged and neutral particles, complementary to the existing CBELSA/TAPS calorimeter which is optimised for multi-photon final states. Selected results of the 12-year CRC period are presented from both experiments.

Can Apparent Diffusion Coefficient Values Assist PI-RADS Version 2 DWI Scoring? A Correlation Study Using the PI-RADSv2 and International Society of Urological Pathology Systems.

PubMed

Gaur, Sonia; Harmon, Stephanie; Rosenblum, Lauren; Greer, Matthew D; Mehralivand, Sherif; Coskun, Mehmet; Merino, Maria J; Wood, Bradford J; Shih, Joanna H; Pinto, Peter A; Choyke, Peter L; Turkbey, Baris

2018-05-07

The purposes of this study were to assess correlation of apparent diffusion coefficient (ADC) and normalized ADC (ratio of tumor to nontumor tissue) with the Prostate Imaging Reporting and Data System version 2 (PI-RADSv2) and updated International Society of Urological Pathology (ISUP) categories and to determine how to optimally use ADC metrics for objective assistance in categorizing lesions within PI-RADSv2 guidelines. In this retrospective study, 100 patients (median age, 62 years; range, 44-75 years; prostate-specific antigen level, 7.18 ng/mL; range, 1.70-84.56 ng/mL) underwent 3-T multiparametric MRI of the prostate with an endorectal coil. Mean ADC was extracted from ROIs based on subsequent prostatectomy specimens. Histopathologic analysis revealed 172 lesions (113 peripheral, 59 transition zone). Two radiologists blinded to histopathologic outcome assigned PI-RADSv2 categories. Kendall tau was used to correlate ADC metrics with PI-RADSv2 and ISUP categories. ROC curves were used to assess the utility of ADC metrics in differentiating each reader's PI-RADSv2 DWI category 4 or 5 assessment in the whole prostate and by zone. ADC metrics negatively correlated with ISUP category in the whole prostate (ADC, τ = -0.21, p = 0.0002; normalized ADC, τ = -0.21, p = 0.0001). Moderate negative correlation was found in expert PI-RADSv2 DWI categories (ADC, τ = -0.34; normalized ADC, τ = -0.31; each p < 0.0001) maintained across zones. In the whole prostate, AUCs of ADC and normalized ADC were 87% and 82% for predicting expert PI-RADSv2 DWI category 4 or 5. A derived optimal cutoff ADC less than 1061 and normalized ADC less than 0.65 achieved positive predictive values of 83% and 84% for correct classification of PI-RADSv2 DWI category 4 or 5 by an expert reader. Consistent relations and predictive values were found by an independent novice reader. ADC and normalized ADC inversely correlate with PI-RADSv2 and ISUP categories and can serve as quantitative metrics to

Search for penguin decays of B mesons at CDF

NASA Astrophysics Data System (ADS)

Kordas, Kostas

Using a data sample of integrated luminosity ∫ Ldt = 28.9 +/- 1.2 pb-1 of proton-antiproton collisions at a center-of-mass energy s = 1.8 TeV collected with the CDF detector at the Fermilab Tevatron collider, we searched for "penguin" radiative decays of B0d and B0s mesons which involve the flavor-changing neutral-current transition of a b quark into an s quark with the emission of a photon, b→sg . Specifically, we searched for the decays B0d→K*0g, K*0→K+p- and B0s→fg, f→K+K- , as well as for the charge conjugate chains. In order to collect such decays, we designed a specialized trigger which required information on all the decay products of the B meson decay chain, the first such trigger in a hadron collider environment. This "penguin" trigger collected data during the last quarter of the 1994--1996 data taking period. After all selection criteria, we are left with one candidate B0d→K*0g decay and no B0s→fg candidates in the entire data sample. We then proceed to set upper limits on the branching fractions of the penguin channels. We exploit the topological similarity between the B¯→e-D0 X,D0→K-p + and the penguin decays, by forming ratios of branching fractions between the penguin and the B¯→e-D0 X channels. Uncertainties associated with the B meson production cross section, common efficiency corrections and other systematic effects are minimal in the ratio of branching fractions. The uncertainty on the B¯→e-D0 X yield is the biggest contribution to the total uncertainty on the penguin branching fraction. We assume equal production rates for B+u and B0d mesons, while the probability of producing B0s mesons relative to B0d mesons, fs/fd, is taken to be 1/3. The inferred upper limits on the ratios of branching fractions are B(B0 s→fg)B( B¯→e-D0 X)<3.5x10-3 at90% C.L. B(B 0d→K*0g) B(B¯→e- D0X)<1.9x10-3 at90%C.L. Relative branching fraction measurements were combined with the branching fraction measurement of the B¯→e-D0 X,D0�

Comparison of theoretical proteomes: identification of COGs with conserved and variable pI within the multimodal pI distribution.

PubMed

Nandi, Soumyadeep; Mehra, Nipun; Lynn, Andrew M; Bhattacharya, Alok

2005-09-09

Theoretical proteome analysis, generated by plotting theoretical isoelectric points (pI) against molecular masses of all proteins encoded by the genome show a multimodal distribution for pI. This multimodal distribution is an effect of allowed combinations of the charged amino acids, and not due to evolutionary causes. The variation in this distribution can be correlated to the organisms ecological niche. Contributions to this variation maybe mapped to individual proteins by studying the variation in pI of orthologs across microorganism genomes. The distribution of ortholog pI values showed trimodal distributions for all prokaryotic genomes analyzed, similar to whole proteome plots. Pairwise analysis of pI variation show that a few COGs are conserved within, but most vary between, the acidic and basic regions of the distribution, while molecular mass is more highly conserved. At the level of functional grouping of orthologs, five groups vary significantly from the population of orthologs, which is attributed to either conservation at the level of sequences or a bias for either positively or negatively charged residues contributing to the function. Individual COGs conserved in both the acidic and basic regions of the trimodal distribution are identified, and orthologs that best represent the variation in levels of the acidic and basic regions are listed. The analysis of pI distribution by using orthologs provides a basis for resolution of theoretical proteome comparison at the level of individual proteins. Orthologs identified that significantly vary between the major acidic and basic regions maybe used as representative of the variation of the entire proteome.

Comparison of theoretical proteomes: Identification of COGs with conserved and variable pI within the multimodal pI distribution

PubMed Central

Nandi, Soumyadeep; Mehra, Nipun; Lynn, Andrew M; Bhattacharya, Alok

2005-01-01

Background Theoretical proteome analysis, generated by plotting theoretical isoelectric points (pI) against molecular masses of all proteins encoded by the genome show a multimodal distribution for pI. This multimodal distribution is an effect of allowed combinations of the charged amino acids, and not due to evolutionary causes. The variation in this distribution can be correlated to the organisms ecological niche. Contributions to this variation maybe mapped to individual proteins by studying the variation in pI of orthologs across microorganism genomes. Results The distribution of ortholog pI values showed trimodal distributions for all prokaryotic genomes analyzed, similar to whole proteome plots. Pairwise analysis of pI variation show that a few COGs are conserved within, but most vary between, the acidic and basic regions of the distribution, while molecular mass is more highly conserved. At the level of functional grouping of orthologs, five groups vary significantly from the population of orthologs, which is attributed to either conservation at the level of sequences or a bias for either positively or negatively charged residues contributing to the function. Individual COGs conserved in both the acidic and basic regions of the trimodal distribution are identified, and orthologs that best represent the variation in levels of the acidic and basic regions are listed. Conclusion The analysis of pI distribution by using orthologs provides a basis for resolution of theoretical proteome comparison at the level of individual proteins. Orthologs identified that significantly vary between the major acidic and basic regions maybe used as representative of the variation of the entire proteome. PMID:16150155

Suppressed Decays of Ds+ Mesons to Two Pseudoscalar Mesons

NASA Astrophysics Data System (ADS)

Adams, G. S.; Anderson, M.; Cummings, J. P.; Danko, I.; Hu, D.; Moziak, B.; Napolitano, J.; He, Q.; Insler, J.; Muramatsu, H.; Park, C. S.; Thorndike, E. H.; Yang, F.; Artuso, M.; Blusk, S.; Khalil, S.; Li, J.; Menaa, N.; Mountain, R.; Nisar, S.; Randrianarivony, K.; Sia, R.; Skwarnicki, T.; Stone, S.; Wang, J. C.; Bonvicini, G.; Cinabro, D.; Dubrovin, M.; Lincoln, A.; Asner, D. M.; Edwards, K. W.; Naik, P.; Briere, R. A.; Ferguson, T.; Tatishvili, G.; Vogel, H.; Watkins, M. E.; Rosner, J. L.; Adam, N. E.; Alexander, J. P.; Cassel, D. G.; Duboscq, J. E.; Ehrlich, R.; Fields, L.; Gibbons, L.; Gray, R.; Gray, S. W.; Hartill, D. L.; Heltsley, B. K.; Hertz, D.; Jones, C. D.; Kandaswamy, J.; Kreinick, D. L.; Kuznetsov, V. E.; Mahlke-Krüger, H.; Mohapatra, D.; Onyisi, P. U. E.; Patterson, J. R.; Peterson, D.; Riley, D.; Ryd, A.; Sadoff, A. J.; Shi, X.; Stroiney, S.; Sun, W. M.; Wilksen, T.; Athar, S. B.; Patel, R.; Yelton, J.; Rubin, P.; Eisenstein, B. I.; Karliner, I.; Lowrey, N.; Selen, M.; White, E. J.; Wiss, J.; Mitchell, R. E.; Shepherd, M. R.; Besson, D.; Pedlar, T. K.; Cronin-Hennessy, D.; Gao, K. Y.; Hietala, J.; Kubota, Y.; Klein, T.; Lang, B. W.; Poling, R.; Scott, A. W.; Zweber, P.; Dobbs, S.; Metreveli, Z.; Seth, K. K.; Tomaradze, A.; Ernst, J.; Ecklund, K. M.; Severini, H.; Love, W.; Savinov, V.; Lopez, A.; Mehrabyan, S.; Mendez, H.; Ramirez, J.; Ge, J. Y.; Miller, D. H.; Sanghi, B.; Shipsey, I. P. J.; Xin, B.

2007-11-01

Using data collected near the Ds*+Ds- peak production energy Ecm=4170MeV by the CLEO-c detector, we study the decays of Ds+ mesons to two pseudoscalar mesons. We report on searches for the singly Cabibbo-suppressed Ds+ decay modes K+η, K+η', π+KS0, K+π0, and the isospin-forbidden decay mode Ds+→π+π0. We normalize with respect to the Cabibbo-favored Ds+ modes π+η, π+η', and K+KS0, and obtain ratios of branching fractions: B(Ds+→K+η)/B(Ds+→π+η)=(8.9±1.5±0.4)%, B(Ds+→K+η')/B(Ds+→π+η')=(4.2±1.3±0.3)%, B(Ds+→π+KS0)/B(Ds+→K+KS0)=(8.2±0.9±0.2)%, B(Ds+→K+π0)/B(Ds+→K+KS0)=(5.5±1.3±0.7)%, and B(Ds+→π+π0)/B(Ds+→K+KS0)<4.1% at 90% C.L., where the uncertainties are statistical and systematic, respectively.

Analysis of PI3K/mTOR Pathway Biomarkers and Their Prognostic Value in Women with Hormone Receptor–Positive, HER2-Negative Early Breast Cancer1

PubMed Central

Azim, Hamdy A.; Kassem, Loay; Treilleux, Isabelle; Wang, Qing; El Enein, Mona Abu; Anis, Shady E.; Bachelot, Thomas

2016-01-01

BACKGROUND: The PI3K/AKT/mTOR pathway alterations have been shown to play significant roles in the development, progression, and metastatic spread of breast cancer. Furthermore, they have been implicated in the process of drug resistance, especially endocrinal therapies. In this study, we aimed to define the correlation between the PI3K mutations and the expression of the phosphorylated forms of different downstream molecules in women with estrogen receptor (ER)–positive, human epidermal growth factor receptor 2–negative (luminal) early breast cancer treated at Cairo university hospitals. METHODS: Next-generation sequencing was used to detect mutations in the PIK3CA hotspots (in exons 9 and 20). Immunohistochemistry was performed on tissue microarray blocks prepared from samples of 35 Egyptian luminal breast cancer patients in the pathology department of Centre Léon Bérard (CLB). The intensity and the percentage of stained tumor cells were integrated to define high versus low biomarker expression. The cytoplasmic and nuclear stainings were graded separately. Patients were followed for a median of 4.7 years (2.1 to 6.9 years). Correlation was done between PI3K mutations and the immunohistochemistry expression of pAKT, LKB1, p4EBP1, and pS6 ribosomal protein (pS6RP) with the clinicopathologic features and disease free survival (DFS) of the patients. RESULTS: Median age at diagnosis was 51.3 years (range, 25 to 82 years). Tumors were larger than 20 mm in 79.2% of the cases, whereas 57.9% had axillary lymph node deposits. Only 12.3% of the patients had SBR grade I tumors, 50.8% had grade II, and 36.8% had grade III. ERs were negative in 6 patients (17%) after pathology review. Thirty-two cases were assessable for LKB1 and pAKT, 33 for p4EBP1 and pS6RP, and 24 for PI3K mutations. Nuclear LKB1, cytoplasmic LKB1, nuclear pAKT, cytoplasmic pAKT, nuclear p4EBP1, and cytoplasmic pS6RP expression was high in 65.6%, 62.5%, 62.5%, 68.8%, 42.4%, and 57.6%, respectively

Organic materials and devices for detecting ionizing radiation

DOEpatents

Doty, F Patrick [Livermore, CA; Chinn, Douglas A [Livermore, CA

2007-03-06

A .pi.-conjugated organic material for detecting ionizing radiation, and particularly for detecting low energy fission neutrons. The .pi.-conjugated materials comprise a class of organic materials whose members are intrinsic semiconducting materials. Included in this class are .pi.-conjugated polymers, polyaromatic hydrocarbon molecules, and quinolates. Because of their high resistivities (.gtoreq.10.sup.9 ohmcm), these .pi.-conjugated organic materials exhibit very low leakage currents. A device for detecting and measuring ionizing radiation can be made by applying an electric field to a layer of the .pi.-conjugated polymer material to measure electron/hole pair formation. A layer of the .pi.-conjugated polymer material can be made by conventional polymer fabrication methods and can be cast into sheets capable of covering large areas. These sheets of polymer radiation detector material can be deposited between flexible electrodes and rolled up to form a radiation detector occupying a small volume but having a large surface area. The semiconducting polymer material can be easily fabricated in layers about 10 .mu.m to 100 .mu.m thick. These thin polymer layers and their associated electrodes can be stacked to form unique multi-layer detector arrangements that occupy small volume.

Photoproduction of Mesons on Quasi-Free Nucleons

NASA Astrophysics Data System (ADS)

Keshelashvili, I.

2014-11-01

The investigation of excited baryon states is important to understand the underling nature/symmetries of hadronic matter. Historically, the first nucleon excitation experiments have been done using charged pion and kaon secondary beams. Later the antiproton-proton scattering has also been involved. However, since the beginning of the 90's meson photoproduction reactions have been considered as a powerful tool in baryon spectroscopy. In this contribution, we overview our experimental programs conducted at the bremsstrahlung photon beams of the MAMI accelerator in Mainz and the ELSA accelerator in Bonn. The results are differential and total cross sections for photoproduction of light neutral mesons and of meson pairs off quasi-free nucleons bound in the deuteron (and sometimes other light nuclei). The scientific programs of this experiments also include single and double polarization measurements as well.

Phosphoinositide 5-phosphatase activities control cell motility in glioblastoma: Two phosphoinositides PI(4,5)P2 and PI(3,4)P2 are involved.

PubMed

Ramos, Ana Raquel; Elong Edimo, William's; Erneux, Christophe

2018-01-01

Inositol polyphosphate 5-phosphatases or phosphoinositide 5-phosphatases (PI 5-phosphatases) are enzymes that can act on soluble inositol phosphates and/or phosphoinositides (PIs). Several PI 5-phosphatases have been linked to human genetic diseases, in particular the Lowe protein or OCRL which is mutated in the Lowe syndrome. There are 10 different members of this family and 9 of them can use PIs as substrate. One of these substrates, PI(3,4,5)P3 binds to specific PH domains and recruits as effectors specific proteins to signaling complexes. Protein kinase B is one target protein and activation of the kinase will have a major impact on cell proliferation, survival and cell metabolism. Two other PIs, PI(4,5)P2 and PI(3,4)P2, are produced or used as substrates of PI 5-phosphatases (OCRL, INPP5B, SHIP1/2, SYNJ1/2, INPP5K, INPP5J, INPP5E). The inositol lipids may influence many aspects of cytoskeletal organization, lamellipodia formation and F-actin polymerization. PI 5-phosphatases have been reported to control cell migration, adhesion, polarity and cell invasion particularly in cancer cells. In glioblastoma, reducing SHIP2 expression can positively or negatively affect the speed of cell migration depending on the glioblastoma cell type. The two PI 5-phosphatases SHIP2 or SKIP could be localized at the plasma membrane and can reduce either PI(3,4,5)P3 or PI(4,5)P2 abundance. In the glioblastoma 1321 N1 cells, SHIP2 controls plasma membrane PI(4,5)P2 thereby participating in the control of cell migration. Copyright © 2017 Elsevier Ltd. All rights reserved.

Acoustic manipulation of oscillating spherical bodies: Emergence of axial negative acoustic radiation force

NASA Astrophysics Data System (ADS)

Rajabi, Majid; Mojahed, Alireza

2016-11-01

In this paper, emergence of negative axial acoustic radiation force on a rigid oscillating spherical body is investigated for acoustic manipulation purposes. The problem of plane acoustic wave scattering from an oscillating spherical body submerged in an ideal acoustic fluid medium is solved. For the case of oscillating direction collinear with the wave propagation wave number vector (desired path), it has been shown that the acoustic radiation force, as a result of nonlinear acoustic wave interaction with bodies can be expressed as a linear function of incident wave field and the oscillation properties of the oscillator (i.e., amplitude and phase of oscillation). The negative (i.e., pulling effects) and positive (i.e., pushing effects) radiation force situations are divided in oscillation complex plane with a specific frequency-dependant straight line. This characteristic line defines the radiation force cancellation state. In order to investigate the stability of the mentioned manipulation strategy, the case of misaligned oscillation of sphere with the wave propagation direction is studied. The proposed methodology may suggest a novel concept of single-beam acoustic handling techniques based on smart carriers.

Toward the excited isoscalar meson spectrum from lattice QCD

DOE PAGES

Dudek, Jozef J.; Edwards, Robert G.; Guo, Peng; ...

2013-11-18

We report on the extraction of an excited spectrum of isoscalar mesons using lattice QCD. Calculations on several lattice volumes are performed with a range of light quark masses corresponding to pion masses down to about ~400 MeV. The distillation method enables us to evaluate the required disconnected contributions with high statistical precision for a large number of meson interpolating fields. We find relatively little mixing between light and strange in most J PC channels; one notable exception is the pseudoscalar sector where the approximate SU(3) F octet, singlet structure of the η, η' is reproduced. We extract exotic Jmore » PC states, identified as hybrid mesons in which an excited gluonic field is coupled to a color-octet qqbar pair, along with non-exotic hybrid mesons embedded in a qq¯-like spectrum.« less

A Diffusion Cloud Chamber Study of Very Slow Mesons. II. Beta Decay of the Muon

DOE R&D Accomplishments Database

Lederman, L. M.; Sargent, C. P.; Rinehart, M.; Rogers, K.

1955-03-01

The spectrum of electrons arising from the decay of the negative mu meson has been determined. The muons are arrested in the gas of a high pressure hydrogen filled diffusion cloud chamber. The momenta of the decay electrons are determined from their curvature in a magnetic field of 7750 gauss. The spectrum of 415 electrons has been analyzed according to the theory of Michel.

Determining the meson-nucleus potential - on the way to mesic states

NASA Astrophysics Data System (ADS)

Metag, Volker

2015-08-01

Experimental approaches to determine the real and imaginary part of the meson-nucleus potential are described. The experiments have been performed with the Crystal Barrel/TAPS detector at the electron accelerator ELSA (Bonn) and the Crystal Ball/TAPS detector at MAMI (Mainz). Measuring the transparency ratio as well as the excitation function and momentum distribution for photo production of ω and η' mesons, the imaginary part of the η'-nucleus potential is found to be smaller than the real part. In case of the ω meson the opposite is observed. This makes the η' meson a good candidate for the search for meson-nucleus bound states while no resolved ω mesic states can be expected. The results are discussed and compared to theoretical predictions. An outlook on future experiments is given.

Latest results from meson photoproduction at ELSA and MAMI

NASA Astrophysics Data System (ADS)

Krusche, B.

2014-06-01

Photoproduction of mesons plays a key role for the investigation of the excitation spectrum of the nucleon and thus for our understanding of the strong interaction in the non-perturbative regime. In this contribution we discuss recent results from the experiments at the tagged photon beams of the electron accelerators ELSA in Bonn and MAMI in Mainz. They include the measurement of cross sections and (double) polarization observables for single meson production and production of meson pairs off free protons as well as of quasi-free nucleons bound in light nuclei (in particular the deuteron).

Computational studies of Ras and PI3K

NASA Technical Reports Server (NTRS)

Ren, Lei; Cucinotta, Francis A.

2004-01-01

Until recently, experimental techniques in molecular cell biology have been the primary means to investigate biological risk upon space radiation. However, computational modeling provides an alternative theoretical approach, which utilizes various computational tools to simulate proteins, nucleotides, and their interactions. In this study, we are focused on using molecular mechanics (MM) and molecular dynamics (MD) to study the mechanism of protein-protein binding and to estimate the binding free energy between proteins. Ras is a key element in a variety of cell processes, and its activation of phosphoinositide 3-kinase (PI3K) is important for survival of transformed cells. Different computational approaches for this particular study are presented to calculate the solvation energies and binding free energies of H-Ras and PI3K. The goal of this study is to establish computational methods to investigate the roles of different proteins played in the cellular responses to space radiation, including modification of protein function through gene mutation, and to support the studies in molecular cell biology and theoretical kinetics models for our risk assessment project.

VizieR Online Data Catalog: H2 d3{Pi}u excitation by elec

NASA Astrophysics Data System (ADS)

Liu, X.; Shemansky, D. E.; Yoshii, J.; Johnson, P. V.; Malone, C. P.; Ajello, J. M.

2016-05-01

Electron-impact excitation of H2 triplet states plays an imp role in the heating of outer planet upper thermospheres. The d3{Pi}u state is the third ungerade triplet state, and the d3{Pi}u-a3{Sigma}g+ emission is the largest cascade channel for the a3{Sigma}g+ state. Accurate energies of the d3{Pi}u-(v, J) levels are calculated from an ab initio potential energy curve. Radiative lifetimes of the d3{Pi}u(v,J) levels are obtained by an accurate evaluation of the d3{Pi}u-a3{Sigma}g+ transition probabilities. The emission yields are determined from experimental lifetimes and calculated radiative lifetimes and are further verified by comparing experimental and synthetic d3{Pi}u-a3{Sigma}g+ spectra at 20eV impact energy. Spectral analysis revealed that multipolar components beyond the dipolar term are required to model the X1{Sigma}g+-d3{Pi}u excitation, and significant cascade excitation occurs at the d3{Pi}u (v=0,1) levels. Kinetic energy (Ek) distributions of H atoms produced via predissociation of the 3{Pi}u state and the d3{Pi}u-a3{Sigma}g+-b3{Sigma}u+ cascade dissociative emission are obtained. Predissociation of the d3{Pi}u state produces H atoms with an average Ek of 2.3+/-0.4 eV/atom, while the Ekdistribution of the d3{Pi}u-a3{Sigma}g+-b3{Sigma}u+ channel is similar to that of the X1{Sigma}g+-a3{Sigma}g+-b3{Sigma}u+ channel and produces H(1s) atoms with an average Ek of 1.15+/-0.05eV/atom. On average, each H2 excited to the d3{Pi}u state in an H2-dominated atmosphere deposits 3.3+/-0.4eV into the atmosphere, while each H2directly excited to the a3{Sigma}g+ state gives 2.2-2.3eV to the atmosphere. The spectral distribution of the calculated a3{Sigma}g+-b3{Sigma}u+ continuum emission due to the X1{Sigma}g+-d3{Pi}u excitation is significantly different from that of direct a3{Sigma}g+ excitation. (2 data files).

Measurement of the Branching Ratio Lambda_c+ -> p pi+ pi- (in Spanish)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lopez-Hinojosa, Guillermo; /San Luis Potosi U.

2008-03-01

The confirmation of the Cabibbo-suppressed charm baryon decay mode {Lambda}{sub c}{sup +} {yields} p{pi}{sup +}{pi}{sup -} is reported. All data analyzed are from SELEX, a fixed target experiment at Fermilab that took data during 1996 and 1997, mainly with a 600 GeV/c {Sigma}{sup -} beam. The branching ratio of the Cabibbo-suppressed decay mode {Lambda}{sub c}{sup +} {yields} p{pi}{sup +}{pi}{sup -} relative to the Cabibbo-favored mode {Lambda}{sub c}{sup +} {yields} pK{sup -}{pi}{sup +} is measured to be: {Gamma}({Lambda}{sub c}{sup +} {yields} p{pi}{sup +}{pi}{sup -})/{Gamma}({Lambda}{sub c}{sup +} {yields} pK{sup -}{pi}{sup +}) = 0.103 {+-} 0.022.

Evidence for the decay D0-->K(-)pi(+)pi(-)e(+)nu(e).

PubMed

Artuso, M; Blusk, S; Butt, J; Li, J; Menaa, N; Mountain, R; Nisar, S; Randrianarivony, K; Sia, R; Skwarnicki, T; Stone, S; Wang, J C; Zhang, K; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Asner, D M; Edwards, K W; Naik, P; Briere, R A; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Adam, N E; Alexander, J P; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Galik, R S; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Mohapatra, D; Onyisi, P U E; Patterson, J R; Peterson, D; Pivarski, J; Riley, D; Ryd, A; Sadoff, A J; Schwarthoff, H; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Athar, S B; Patel, R; Potlia, V; Yelton, J; Rubin, P; Cawlfield, C; Eisenstein, B I; Karliner, I; Kim, D; Lowrey, N; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Smith, A; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A; Ernst, J; Ecklund, K M; Severini, H; Love, W; Savinov, V; Aquines, O; Lopez, A; Mehrabyan, S; Mendez, H; Ramirez, J; Huang, G S; Miller, D H; Pavlunin, V; Sanghi, B; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J; He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F

2007-11-09

Using a 281 pb{-1} data sample collected at the psi(3770) with the CLEO-c detector, we present the first absolute branching fraction measurement of the decay D0-->K(-)pi(+)pi(-)e(+)nu(e) at a statistical significance of about 4.0 standard deviations. We find 10 candidates consistent with the decay D0-->K(-)pi(+)pi(-)e(+)nu(e). The probability that a background fluctuation accounts for this signal is less than 4.1 x 10{-5}. We find B(D0-->K(-)pi(+)pi(-)e(+)nu(e)) = [2.8{-1.1}{+1.4}(stat)+/-0.3(syst)]x10{-4}. By restricting the invariant mass of the hadronic system to be consistent with K1(1270), we obtain the product of branching fractions B(D{0}-->K{1}{-}(1270)e{+}nu{e})xB(K1-(1270)-->K{-}pi{+}pi{-})=[2.5{-1.0}{+1.3}(stat)+/-0.2(syst)]x10{-4}. Using B(K1-(1270)-->K{-}pi{+}pi{-})=(33+/-3)%, we obtain B(D{0}-->K{1}{-}(1270)e{+}nu{e})=[7.6{-3.0}{+4.1}(stat)+/-0.6(syst)+/-0.7]x10{-4}. The last error accounts for the uncertainties in the measured K1-(1270)-->K{-}pi{+}pi{-} branching fractions.

Measurement of resonance parameters of orbitally excited narrow B0 mesons.

PubMed

Aaltonen, T; Adelman, J; Akimoto, T; Albrow, M G; González, B Alvarez; Amerio, S; Amidei, D; Anastassov, A; Annovi, A; Antos, J; Apollinari, G; Apresyan, A; Arisawa, T; Artikov, A; Ashmanskas, W; Attal, A; Aurisano, A; Azfar, F; Azzurri, P; Badgett, W; Barbaro-Galtieri, A; Barnes, V E; Barnett, B A; Bartsch, V; Bauer, G; Beauchemin, P-H; Bedeschi, F; Beecher, D; Behari, S; Bellettini, G; Bellinger, J; Benjamin, D; Beretvas, A; Beringer, J; Bhatti, A; Binkley, M; Bisello, D; Bizjak, I; Blair, R E; Blocker, C; Blumenfeld, B; Bocci, A; Bodek, A; Boisvert, V; Bolla, G; Bortoletto, D; Boudreau, J; Boveia, A; Brau, B; Bridgeman, A; Brigliadori, L; Bromberg, C; Brubaker, E; Budagov, J; Budd, H S; Budd, S; Burke, S; Burkett, K; Busetto, G; Bussey, P; Buzatu, A; Byrum, K L; Cabrera, S; Calancha, C; Campanelli, M; Campbell, M; Canelli, F; Canepa, A; Carls, B; Carlsmith, D; Carosi, R; Carrillo, S; Carron, S; Casal, B; Casarsa, M; Castro, A; Catastini, P; Cauz, D; Cavaliere, V; Cavalli-Sforza, M; Cerri, A; Cerrito, L; Chang, S H; Chen, Y C; Chertok, M; Chiarelli, G; Chlachidze, G; Chlebana, F; Cho, K; Chokheli, D; Chou, J P; Choudalakis, G; Chuang, S H; Chung, K; Chung, W H; Chung, Y S; Chwalek, T; Ciobanu, C I; Ciocci, M A; Clark, A; Clark, D; Compostella, G; Convery, M E; Conway, J; Cordelli, M; Cortiana, G; Cox, C A; Cox, D J; Crescioli, F; Almenar, C Cuenca; Cuevas, J; Culbertson, R; Cully, J C; Dagenhart, D; Datta, M; Davies, T; de Barbaro, P; De Cecco, S; Deisher, A; De Lorenzo, G; Dell'orso, M; Deluca, C; Demortier, L; Deng, J; Deninno, M; Derwent, P F; di Giovanni, G P; Dionisi, C; Di Ruzza, B; Dittmann, J R; D'Onofrio, M; Donati, S; Dong, P; Donini, J; Dorigo, T; Dube, S; Efron, J; Elagin, A; Erbacher, R; Errede, D; Errede, S; Eusebi, R; Fang, H C; Farrington, S; Fedorko, W T; Feild, R G; Feindt, M; Fernandez, J P; Ferrazza, C; Field, R; Flanagan, G; Forrest, R; Frank, M J; Franklin, M; Freeman, J C; Furic, I; Gallinaro, M; Galyardt, J; Garberson, F; Garcia, J E; Garfinkel, A F; Genser, K; Gerberich, H; Gerdes, D; Gessler, A; Giagu, S; Giakoumopoulou, V; Giannetti, P; Gibson, K; Gimmell, J L; Ginsburg, C M; Giokaris, N; Giordani, M; Giromini, P; Giunta, M; Giurgiu, G; Glagolev, V; Glenzinski, D; Gold, M; Goldschmidt, N; Golossanov, A; Gomez, G; Gomez-Ceballos, G; Goncharov, M; González, O; Gorelov, I; Goshaw, A T; Goulianos, K; Gresele, A; Grinstein, S; Grosso-Pilcher, C; Grundler, U; da Costa, J Guimaraes; Gunay-Unalan, Z; Haber, C; Hahn, K; Hahn, S R; Halkiadakis, E; Han, B-Y; Han, J Y; Happacher, F; Hara, K; Hare, D; Hare, M; Harper, S; Harr, R F; Harris, R M; Hartz, M; Hatakeyama, K; Hays, C; Heck, M; Heijboer, A; Heinrich, J; Henderson, C; Herndon, M; Heuser, J; Hewamanage, S; Hidas, D; Hill, C S; Hirschbuehl, D; Hocker, A; Hou, S; Houlden, M; Hsu, S-C; Huffman, B T; Hughes, R E; Husemann, U; Huston, J; Incandela, J; Introzzi, G; Iori, M; Ivanov, A; James, E; Jayatilaka, B; Jeon, E J; Jha, M K; Jindariani, S; Johnson, W; Jones, M; Joo, K K; Jun, S Y; Jung, J E; Junk, T R; Kamon, T; Kar, D; Karchin, P E; Kato, Y; Kephart, R; Keung, J; Khotilovich, V; Kilminster, B; Kim, D H; Kim, H S; Kim, H W; Kim, J E; Kim, M J; Kim, S B; Kim, S H; Kim, Y K; Kimura, N; Kirsch, L; Klimenko, S; Knuteson, B; Ko, B R; Kondo, K; Kong, D J; Konigsberg, J; Korytov, A; Kotwal, A V; Kreps, M; Kroll, J; Krop, D; Krumnack, N; Kruse, M; Krutelyov, V; Kubo, T; Kuhr, T; Kulkarni, N P; Kurata, M; Kusakabe, Y; Kwang, S; Laasanen, A T; Lami, S; Lammel, S; Lancaster, M; Lander, R L; Lannon, K; Lath, A; Latino, G; Lazzizzera, I; Lecompte, T; Lee, E; Lee, H S; Lee, S W; Leone, S; Lewis, J D; Lin, C-S; Linacre, J; Lindgren, M; Lipeles, E; Lister, A; Litvintsev, D O; Liu, C; Liu, T; Lockyer, N S; Loginov, A; Loreti, M; Lovas, L; Lucchesi, D; Luci, C; Lueck, J; Lujan, P; Lukens, P; Lungu, G; Lyons, L; Lys, J; Lysak, R; Macqueen, D; Madrak, R; Maeshima, K; Makhoul, K; Maki, T; Maksimovic, P; Malde, S; Malik, S; Manca, G; Manousakis-Katsikakis, A; Margaroli, F; Marino, C; Marino, C P; Martin, A; Martin, V; Martínez, M; Martínez-Ballarín, R; Maruyama, T; Mastrandrea, P; Masubuchi, T; Mathis, M; Mattson, M E; Mazzanti, P; McFarland, K S; McIntyre, P; McNulty, R; Mehta, A; Mehtala, P; Menzione, A; Merkel, P; Mesropian, C; Miao, T; Miladinovic, N; Miller, R; Mills, C; Milnik, M; Mitra, A; Mitselmakher, G; Miyake, H; Moggi, N; Moon, C S; Moore, R; Morello, M J; Morlok, J; Fernandez, P Movilla; Mülmenstädt, J; Mukherjee, A; Muller, Th; Mumford, R; Murat, P; Mussini, M; Nachtman, J; Nagai, Y; Nagano, A; Naganoma, J; Nakamura, K; Nakano, I; Napier, A; Necula, V; Nett, J; Neu, C; Neubauer, M S; Neubauer, S; Nielsen, J; Nodulman, L; Norman, M; Norniella, O; Nurse, E; Oakes, L; Oh, S H; Oh, Y D; Oksuzian, I; Okusawa, T; Orava, R; Griso, S Pagan; Palencia, E; Papadimitriou, V; Papaikonomou, A; Paramonov, A A; Parks, B; Pashapour, S; Patrick, J; Pauletta, G; Paulini, M; Paus, C; Peiffer, T; Pellett, D E; Penzo, A; Phillips, T J; Piacentino, G; Pianori, E; Pinera, L; Pitts, K; Plager, C; Pondrom, L; Poukhov, O; Pounder, N; Prakoshyn, F; Pronko, A; Proudfoot, J; Ptohos, F; Pueschel, E; Punzi, G; Pursley, J; Rademacker, J; Rahaman, A; Ramakrishnan, V; Ranjan, N; Redondo, I; Rekovic, V; Renton, P; Renz, M; Rescigno, M; Richter, S; Rimondi, F; Ristori, L; Robson, A; Rodrigo, T; Rodriguez, T; Rogers, E; Rolli, S; Roser, R; Rossi, M; Rossin, R; Roy, P; Ruiz, A; Russ, J; Rusu, V; Safonov, A; Sakumoto, W K; Saltó, O; Santi, L; Sarkar, S; Sartori, L; Sato, K; Savoy-Navarro, A; Schlabach, P; Schmidt, A; Schmidt, E E; Schmidt, M A; Schmidt, M P; Schmitt, M; Schwarz, T; Scodellaro, L; Scribano, A; Scuri, F; Sedov, A; Seidel, S; Seiya, Y; Semenov, A; Sexton-Kennedy, L; Sforza, F; Sfyrla, A; Shalhout, S Z; Shears, T; Shepard, P F; Shimojima, M; Shiraishi, S; Shochet, M; Shon, Y; Shreyber, I; Sidoti, A; Sinervo, P; Sisakyan, A; Slaughter, A J; Slaunwhite, J; Sliwa, K; Smith, J R; Snider, F D; Snihur, R; Soha, A; Somalwar, S; Sorin, V; Spalding, J; Spreitzer, T; Squillacioti, P; Stanitzki, M; St Denis, R; Stelzer, B; Stelzer-Chilton, O; Stentz, D; Strologas, J; Strycker, G L; Stuart, D; Suh, J S; Sukhanov, A; Suslov, I; Suzuki, T; Taffard, A; Takashima, R; Takeuchi, Y; Tanaka, R; Tecchio, M; Teng, P K; Terashi, K; Thom, J; Thompson, A S; Thompson, G A; Thomson, E; Tipton, P; Ttito-Guzmán, P; Tkaczyk, S; Toback, D; Tokar, S; Tollefson, K; Tomura, T; Tonelli, D; Torre, S; Torretta, D; Totaro, P; Tourneur, S; Trovato, M; Tsai, S-Y; Tu, Y; Turini, N; Ukegawa, F; Vallecorsa, S; van Remortel, N; Varganov, A; Vataga, E; Vázquez, F; Velev, G; Vellidis, C; Veszpremi, V; Vidal, M; Vidal, R; Vila, I; Vilar, R; Vine, T; Vogel, M; Volobouev, I; Volpi, G; Wagner, P; Wagner, R G; Wagner, R L; Wagner, W; Wagner-Kuhr, J; Wakisaka, T; Wallny, R; Wang, S M; Warburton, A; Waters, D; Weinberger, M; Weinelt, J; Wester, W C; Whitehouse, B; Whiteson, D; Wicklund, A B; Wicklund, E; Wilbur, S; Williams, G; Williams, H H; Wilson, P; Winer, B L; Wittich, P; Wolbers, S; Wolfe, C; Wright, T; Wu, X; Würthwein, F; Wynne, S M; Xie, S; Yagil, A; Yamamoto, K; Yamaoka, J; Yang, U K; Yang, Y C; Yao, W M; Yeh, G P; Yoh, J; Yorita, K; Yoshida, T; Yu, G B; Yu, I; Yu, S S; Yun, J C; Zanello, L; Zanetti, A; Zhang, X; Zheng, Y; Zucchelli, S

2009-03-13

We report a measurement of resonance parameters of the orbitally excited (L=1) narrow B0 mesons in decays to B;{(*)+}pi;{-} using 1.7 fb;{-1} of data collected by the CDF II detector at the Fermilab Tevatron. The mass and width of the B_{2};{*0} state are measured to be m(B_{2};{*0})=5740.2_{-1.8};{+1.7}(stat)-0.8+0.9(syst) MeV/c;{2} and Gamma(B_{2};{*0})=22.7_{-3.2};{+3.8}(stat)-10.2+3.2(syst) MeV/c;{2}. The mass difference between the B_{2};{*0} and B10 states is measured to be 14.9_{-2.5};{+2.2}(stat)-1.4+1.2(syst) MeV/c;{2}, resulting in a B10 mass of 5725.3_{-2.2};{+1.6}(stat)-1.5+1.4(syst) MeV/c;{2}. This is currently the most precise measurement of the masses of these states and the first measurement of the B_{2};{*0} width.

Mesonic Decay of Charm Hypernuclei Λc+

NASA Astrophysics Data System (ADS)

Ghosh, Sabyasachi; Fontoura, Carlos E.; Krein, Gastão

2016-03-01

Λc+ hypernuclei are expected to have binding energies and other properties similar to those of strange hypernuclei in view of the similarity between the quark structures of the strange and charmed hyperons, namely Λ(uds) and Λc+(udc). One striking difference however occurs in their mesonic decays, as there is almost no Pauli blocking in the nucleonic decay of a charm hypernucleus because the final-state nucleons leave the nucleus at high energies. The nuclear medium nevertheless affects the mesonic decays of charm hypernucleus because the nuclear mean fields modify the masses of the charm hyperon. In the present communication we present results of a first investigation of the effects of finite baryon density on different weak mesonic decay channels of the Λc+ baryon. We found a non-negligible reduction of the decay widths as compared to their vacuum values.

Coherent vector meson photoproduction from deuterium at intermediate energies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rogers, T.C.; Strikman, M.I.; Sargsian, M.M.

2006-04-15

We analyze the cross section for vector meson photoproduction off a deuteron for the intermediate range of photon energies starting at a few giga-electron-volts above the threshold and higher. We reproduce the steps in the derivation of the conventional nonrelativistic Glauber expression based on an effective diagrammatic method while making corrections for Fermi motion and intermediate-energy kinematic effects. We show that, for intermediate-energy vector meson production, the usual Glauber factorization breaks down, and we derive corrections to the usual Glauber method to linear order in longitudinal nucleon momentum. The purpose of our analysis is to establish methods for probing interestingmore » physics in the production mechanism for {phi} mesons and heavier vector mesons. We demonstrate how neglecting the breakdown of Glauber factorization can lead to errors in measurements of basic cross sections extracted from nuclear data.« less

Vector Meson Production at Hera

NASA Astrophysics Data System (ADS)

Szuba, Dorota

The diffractive production of vector mesons ep→eVMY, with VM=ρ0, ω, ϕ, J/ψ, ψ‧ or ϒ and with Y being either the scattered proton or a low mass hadronic system, has been extensively investigated at HERA. HERA offers a unique opportunity to study the dependences of diffractive processes on different scales: the mass of the vector meson, mVM, the centre-of-mass energy of the γp system, W, the photon virtuality, Q2 and the four-momentum transfer squared at the proton vertex, |t|. Strong interactions can be investigated in the transition from the hard to the soft regime, where the confinement of quarks and gluons occurs.

Cabibbo-Kobayashi-Maskawa-favored B decays to a scalar meson and a D meson

NASA Astrophysics Data System (ADS)

Zou, Zhi-Tian; Li, Ying; Liu, Xin

2017-12-01

In this work, we attempt to study the Cabibbo-Kobayashi-Maskawa-favored B → \\overline{D} S (" S" denoting the scalar meson) decays within the perturbative QCD approach at the leading order and the leading power. Although the light scalar mesons are widely perceived as primarily the four-quark bound states, in practice it is hard for us to make quantitative predictions based on the four-quark picture for light scalars. Hence, we calculate the decays with light scalars in the two-quark model. For the decays with scalar mesons above 1 GeV, we have explored two possible scenarios, depending on whether the light scalars are treated as the lowest lying q\\bar{q} states or four-quark particles. In total, we calculated the branching fractions of 72 decay modes, and most of them are in the range 10^{-4}-10^{-7}, which are measurable in the on-going LHCb experiment and the forthcoming Belle-II experiment. Moreover, since in the standard model these decays occur only through tree operators and have no CP asymmetries, any deviation will be a signal of new physics beyond the standard model. Despite large uncertainties induced by nonperturbative parameters and corrections of high order and high power, our results and discussions will be useful for the on-going LHCb and the forthcoming Belle-II experiments.

Vector meson photoproduction with a linearly polarized beam

NASA Astrophysics Data System (ADS)

Mathieu, V.; Nys, J.; Fernández-Ramírez, C.; Jackura, A.; Pilloni, A.; Sherrill, N.; Szczepaniak, A. P.; Fox, G.; Joint Physics Analysis Center

2018-05-01

We propose a model based on Regge theory to describe photoproduction of light vector mesons. We fit the SLAC data and make predictions for the energy and momentum-transfer dependence of the spin-density matrix elements in photoproduction of ω , ρ0 and ϕ mesons at Eγ˜8.5 GeV , which are soon to be measured at Jefferson Lab.

Pi-Pi contacts are an overlooked protein feature relevant to phase separation.

PubMed

Vernon, Robert McCoy; Chong, Paul Andrew; Tsang, Brian; Kim, Tae Hun; Bah, Alaji; Farber, Patrick; Lin, Hong; Forman-Kay, Julie Deborah

2018-02-09

Protein phase separation is implicated in formation of membraneless organelles, signaling puncta and the nuclear pore. Multivalent interactions of modular binding domains and their target motifs can drive phase separation. However, forces promoting the more common phase separation of intrinsically disordered regions are less understood, with suggested roles for multivalent cation-pi, pi-pi, and charge interactions and the hydrophobic effect. Known phase-separating proteins are enriched in pi-orbital containing residues and thus we analyzed pi-interactions in folded proteins. We found that pi-pi interactions involving non-aromatic groups are widespread, underestimated by force-fields used in structure calculations and correlated with solvation and lack of regular secondary structure, properties associated with disordered regions. We present a phase separation predictive algorithm based on pi interaction frequency, highlighting proteins involved in biomaterials and RNA processing. © 2018, Vernon et al.

Pi-Pi contacts are an overlooked protein feature relevant to phase separation

PubMed Central

Vernon, Robert McCoy; Chong, Paul Andrew; Tsang, Brian; Kim, Tae Hun; Bah, Alaji; Farber, Patrick; Lin, Hong

2018-01-01

Protein phase separation is implicated in formation of membraneless organelles, signaling puncta and the nuclear pore. Multivalent interactions of modular binding domains and their target motifs can drive phase separation. However, forces promoting the more common phase separation of intrinsically disordered regions are less understood, with suggested roles for multivalent cation-pi, pi-pi, and charge interactions and the hydrophobic effect. Known phase-separating proteins are enriched in pi-orbital containing residues and thus we analyzed pi-interactions in folded proteins. We found that pi-pi interactions involving non-aromatic groups are widespread, underestimated by force-fields used in structure calculations and correlated with solvation and lack of regular secondary structure, properties associated with disordered regions. We present a phase separation predictive algorithm based on pi interaction frequency, highlighting proteins involved in biomaterials and RNA processing. PMID:29424691

Was There a Significantly Negative Anomaly of Global Land Surface Net Radiation from 2001-2006?

NASA Astrophysics Data System (ADS)

Liang, S.; Jia, A.; Jiang, B.

2016-12-01

Surface net radiation, which characterizes surface energy budget, can be estimated from in-situ measurements, satellite products, model simulations, and reanalysis. Satellite products are usually validated using ground measurements to characterize their uncertainties. The surface net radiation product from the CERES (Clouds and the Earth's Radiant Energy System) has been widely used. After validating it using extensive ground measurements, we also verified that the CERES surface net radiation product is highly accurate. When we evaluated the temporal variations of the averaged global land surface net radiation from the CERES product, we found a significantly negative anomaly starting from 2001, reaching the maximum in 2004, and gradually coming back to normal in 2006. The valley has the magnitude of approximately 3 Wm-2 centered at 2004. After comparing with the high-resolution GLASS (Global LAnd Surface Satellite) net radiation product developed at Beijing Normal University, the CMIP5 model simulations, and the ERA-Interim reanalysis dataset, we concluded that the significant decreasing pattern of land surface net radiation from 2001-2006 is an artifact mainly due to inaccurate longwave net radiation of the CERES surface net radiation product. The current ground measurement networks are not spatially dense enough to capture the false negative anomaly from the CERES product, which calls for more ground measurements.

Dispersion relations with crossing symmetry for {pi}{pi} D- and F-wave amplitudes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kaminski, R.

A set of once subtracted dispersion relations with imposed crossing symmetry condition for the {pi}{pi} D- and F-wave amplitudes is derived and analyzed. An example of numerical calculations in the effective two-pion mass range from the threshold to 1.1 GeV is presented. It is shown that these new dispersion relations impose quite strong constraints on the analyzed {pi}{pi} interactions and are very useful tools to test the {pi}{pi} amplitudes. One of the goals of this work is to provide a complete set of equations required for easy use. Full analytical expressions are presented. Along with the well-known dispersion relations successfulmore » in testing the {pi}{pi} S- and P-wave amplitudes, those presented here for the D and F waves give a complete set of tools for analyses of the {pi}{pi} interactions.« less

Evidence of N*(1535) resonance contribution in the pn{yields}d{phi} reaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cao Xu; Theoretical Physics Center for Sciences Facilities, Chinese Academy of Sciences, Beijing 100049; Graduate University of Chinese Academy of Sciences, Beijing 100049

2009-08-15

The N*(1535) resonance contributions to the pn{yields}d{phi} reaction are evaluated in an effective Lagrangian model. The {pi}-, {eta}-, and {rho}-meson exchange are considered. It is shown that the contributions from {pi}- and {rho}-meson exchange are dominant, while the contribution from {eta}-meson exchange is negligibly small. Our theoretical results reproduce the experimental data of both total cross section and angular distribution well. This is more evidence that the N*(1535) resonance has a large ss component leading to a large coupling to N{phi}, which may be the real origin of the Okubo-Zweig-Iizuka rule violation in the {pi}N and pN reactions.

Observation of an enhancement in e{sup +}e{sup -}{yields}{Upsilon}(1S){pi}{sup +}{pi}{sup -}, {Upsilon}(2S){pi}{sup +}{pi}{sup -}, and {Upsilon}(3S){pi}{sup +}{pi}{sup -} production near {radical}(s)=10.89 GeV

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, K.-F.; Hou, W.-S.; Chang, P.

2010-11-01

We measure the production cross sections for e{sup +}e{sup -}{yields}{Upsilon}(1S){pi}{sup +}{pi}{sup -}, {Upsilon}(2S){pi}{sup +}{pi}{sup -}, and {Upsilon}(3S){pi}{sup +}{pi}{sup -} as a function of {radical}(s) between 10.83 GeV and 11.02 GeV. The data consist of 8.1 fb{sup -1} collected with the Belle detector at the KEKB e{sup +}e{sup -} collider. We observe enhanced production in all three final states that does not agree well with the conventional {Upsilon}(10860) line shape. A fit using a Breit-Wigner resonance shape yields a peak mass of [10 888.4{sub -2.6}{sup +2.7}(stat){+-}1.2(syst)] MeV/c{sup 2} and a width of [30.7{sub -7.0}{sup +8.3}(stat){+-}3.1(syst)] MeV/c{sup 2}.

Noncoding RNA. piRNA-guided transposon cleavage initiates Zucchini-dependent, phased piRNA production.

PubMed

Han, Bo W; Wang, Wei; Li, Chengjian; Weng, Zhiping; Zamore, Phillip D

2015-05-15

PIWI-interacting RNAs (piRNAs) protect the animal germ line by silencing transposons. Primary piRNAs, generated from transcripts of genomic transposon "junkyards" (piRNA clusters), are amplified by the "ping-pong" pathway, yielding secondary piRNAs. We report that secondary piRNAs, bound to the PIWI protein Ago3, can initiate primary piRNA production from cleaved transposon RNAs. The first ~26 nucleotides (nt) of each cleaved RNA becomes a secondary piRNA, but the subsequent ~26 nt become the first in a series of phased primary piRNAs that bind Piwi, allowing piRNAs to spread beyond the site of RNA cleavage. The ping-pong pathway increases only the abundance of piRNAs, whereas production of phased primary piRNAs from cleaved transposon RNAs adds sequence diversity to the piRNA pool, allowing adaptation to changes in transposon sequence. Copyright © 2015, American Association for the Advancement of Science.

High resolution absorption cross sections for the A2Pi-X2Pi system of ClO

NASA Technical Reports Server (NTRS)

Wine, P. H.; Ravishankara, A. R.; Philen, D. L.; Davis, D. D.; Watson, R. T.

1977-01-01

High-resolution ultraviolet absorption cross-sections for the ClO molecule are obtained, with the aim of facilitating studies of ozone depletion resulting from the injection of chlorofluorocarbons into the atmosphere. The spectroscopic analysis, which involves a frequency-doubled tunable dye laser with a bandwidth of 0.015 A, is described. Studies of the rotational lines of the ClO A 2Pi 3/2-X2Pi 3/2 9-10 band were conducted. Peak cross-sections for the P and R lines of the 9-0 band are found to be 10.0, 9.6, 8.6, 10.6, 10.3, and 9.2 times ten to the negative seventeenth power cm squared, with estimated accuracy of plus or minus 25%. Problems in distinguishing between Cl-35 and Cl-37 absorption are also considered.

Measurement of the branching fractions of B-->D**(l) nu(l) decays in events tagged by a fully reconstructed B meson.

PubMed

Aubert, B; Bona, M; Karyotakis, Y; Lees, J P; Poireau, V; Prencipe, E; Prudent, X; Tisserand, V; Garra Tico, J; Grauges, E; Lopez, L; Palano, A; Pappagallo, M; Eigen, G; Stugu, B; Sun, L; Abrams, G S; Battaglia, M; Brown, D N; Cahn, R N; Jacobsen, R G; Kerth, L T; Kolomensky, Yu G; Lynch, G; Osipenkov, I L; Ronan, M T; Tackmann, K; Tanabe, T; Hawkes, C M; Soni, N; Watson, A T; Koch, H; Schroeder, T; Walker, D; Asgeirsson, D J; Fulsom, B G; Hearty, C; Mattison, T S; Mckenna, J A; Barrett, M; Khan, A; Blinov, V E; Bukin, A D; Buzykaev, A R; Druzhinin, V P; Golubev, V B; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Todyshev, K Yu; Bondioli, M; Curry, S; Eschrich, I; Kirkby, D; Lankford, A J; Lund, P; Mandelkern, M; Martin, E C; Stoker, D P; Abachi, S; Buchanan, C; Gary, J W; Liu, F; Long, O; Shen, B C; Vitug, G M; Yasin, Z; Zhang, L; Sharma, V; Campagnari, C; Hong, T M; Kovalskyi, D; Mazur, M A; Richman, J D; Beck, T W; Eisner, A M; Flacco, C J; Heusch, C A; Kroseberg, J; Lockman, W S; Schalk, T; Schumm, B A; Seiden, A; Wang, L; Wilson, M G; Winstrom, L O; Cheng, C H; Doll, D A; Echenard, B; Fang, F; Hitlin, D G; Narsky, I; Piatenko, T; Porter, F C; Andreassen, R; Mancinelli, G; Meadows, B T; Mishra, K; Sokoloff, M D; Bloom, P C; Ford, W T; Gaz, A; Hirschauer, J F; Nagel, M; Nauenberg, U; Smith, J G; Ulmer, K A; Wagner, S R; Ayad, R; Soffer, A; Toki, W H; Wilson, R J; Altenburg, D D; Feltresi, E; Hauke, A; Jasper, H; Karbach, M; Merkel, J; Petzold, A; Spaan, B; Wacker, K; Kobel, M J; Mader, W F; Nogowski, R; Schubert, K R; Schwierz, R; Sundermann, J E; Volk, A; Bernard, D; Bonneaud, G R; Latour, E; Thiebaux, Ch; Verderi, M; Clark, P J; Gradl, W; Playfer, S; Watson, J E; Andreotti, M; Bettoni, D; Bozzi, C; Calabrese, R; Cecchi, A; Cibinetto, G; Franchini, P; Luppi, E; Negrini, M; Petrella, A; Piemontese, L; Santoro, V; Baldini-Ferroli, R; Calcaterra, A; de Sangro, R; Finocchiaro, G; Pacetti, S; Patteri, P; Peruzzi, I M; Piccolo, M; Rama, M; Zallo, A; Buzzo, A; Contri, R; Lo Vetere, M; Macri, M M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Chaisanguanthum, K S; Morii, M; Marks, J; Schenk, S; Uwer, U; Klose, V; Lacker, H M; Bard, D J; Dauncey, P D; Nash, J A; Panduro Vazquez, W; Tibbetts, M; Behera, P K; Chai, X; Charles, M J; Mallik, U; Cochran, J; Crawley, H B; Dong, L; Meyer, W T; Prell, S; Rosenberg, E I; Rubin, A E; Gao, Y Y; Gritsan, A V; Guo, Z J; Lae, C K; Denig, A G; Fritsch, M; Schott, G; Arnaud, N; Béquilleux, J; D'Orazio, A; Davier, M; Firmino da Costa, J; Grosdidier, G; Höcker, A; Lepeltier, V; Le Diberder, F; Lutz, A M; Pruvot, S; Roudeau, P; Schune, M H; Serrano, J; Sordini, V; Stocchi, A; Wormser, G; Lange, D J; Wright, D M; Bingham, I; Burke, J P; Chavez, C A; Fry, J R; Gabathuler, E; Gamet, R; Hutchcroft, D E; Payne, D J; Touramanis, C; Bevan, A J; Clarke, C K; George, K A; Di Lodovico, F; Sacco, R; Sigamani, M; Cowan, G; Flaecher, H U; Hopkins, D A; Paramesvaran, S; Salvatore, F; Wren, A C; Brown, D N; Davis, C L; Alwyn, K E; Bailey, D; Barlow, R J; Chia, Y M; Edgar, C L; Jackson, G; Lafferty, G D; West, T J; Yi, J I; Anderson, J; Chen, C; Jawahery, A; Roberts, D A; Simi, G; Tuggle, J M; Dallapiccola, C; Li, X; Salvati, E; Saremi, S; Cowan, R; Dujmic, D; Fisher, P H; Koeneke, K; Sciolla, G; Spitznagel, M; Taylor, F; Yamamoto, R K; Zhao, M; Patel, P M; Robertson, S H; Lazzaro, A; Lombardo, V; Palombo, E; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Sanders, D A; Summers, D J; Zhao, H W; Simard, M; Taras, P; Viaud, F B; Nicholson, H; De Nardo, G; Lista, L; Monorchio, D; Onorato, G; Sciacca, C; Raven, G; Snoek, H L; Jessop, C P; Knoepfel, K J; Lo Secco, J M; Wang, W F; Benelli, G; Corwin, L A; Honscheid, K; Kagan, H; Kass, R; Morris, J P; Rahimi, A M; Regensburger, J J; Sekula, S J; Wong, Q K; Blount, N L; Brau, J; Frey, R; Igonkina, O; Kolb, J A; Lu, M; Rahmat, R; Sinev, N B; Strom, D; Strube, J; Torrence, E; Castelli, G; Gagliardi, N; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Voci, C; del Amo Sanchez, P; Ben-Haim, E; Briand, H; Calderini, G; Chauveau, J; David, P; Del Buono, L; Hamon, O; Leruste, Ph; Ocariz, J; Perez, A; Prendki, J; Sitt, S; Gladney, L; Biasini, M; Covarelli, R; Manoni, E; Angelini, C; Batignani, G; Bettarini, S; Carpinelli, M; Cervelli, A; Forti, E; Giorgi, M A; Lusiani, A; Marchiori, G; Morganti, M; Neri, N; Paoloni, E; Rizzo, G; Walsh, J J; Lopes Pegna, D; Lu, C; Olsen, J; Smith, A J S; Telnov, A V; Anulli, F; Baracchini, E; Cavoto, G; del Re, D; Di Marco, E; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Jackson, P D; Li Gioi, L; Mazzoni, M A; Morganti, S; Piredda, G; Polci, F; Renga, F; Voena, C; Ebert, M; Hartmann, T; Schröder, H; Waldi, R; Adye, T; Franek, B; Olaiya, E O; Wilson, F F; Emery, S; Escalier, M; Esteve, L; Ganzhur, S F; Hamel de Monchenault, G; Kozanecki, W; Vasseur, G; Yèche, Ch; Zito, M; Chen, X R; Liu, H; Park, W; Purohit, M V; White, R M; Wilson, J R; Allen, M T; Aston, D; Bartoldus, R; Bechtle, P; Benitez, J F; Cenci, R; Coleman, J P; Convery, M R; Dingfelder, J C; Dorfan, J; Dubois-Felsmann, G P; Dunwoodie, W; Field, R C; Gabareen, A M; Gowdy, S J; Graham, M T; Grenier, P; Hast, C; Innes, W R; Kaminski, J; Kelsey, M H; Kim, H; Kim, P; Kocian, M L; Leith, D W G S; Li, S; Lindquist, B; Luitz, S; Luth, V; Lynch, H L; MacFarlane, D B; Marsiske, H; Messner, R; Muller, D R; Neal, H; Nelson, S; O'Grady, C P; Ofte, I; Perazzo, A; Perl, M; Ratcliff, B N; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Snyder, A; Su, D; sullivan, M K; Suzuki, K; Swain, S K; Thompson, J M; Va'vra, J; Wagner, A P; Weaver, M; West, C A; Wisniewski, W J; Wittgen, M; Wright, D H; Wulsin, H W; Yarritu, A K; Yi, K; Young, C C; Ziegler, V; Burchat, P R; Edwards, A J; Majewski, S A; Miyashita, T S; Petersen, B A; Wilden, L; Ahmed, S; Alam, M S; Ernst, J A; Pan, B; Saeed, M A; Zain, S B; Spanier, S M; Wogsland, B J; Eckmann, R; Ritchie, J L; Ruland, A M; Schilling, C J; Schwitters, R F; Drummond, B W; Izen, J M; Lou, X C; Bianchi, F; Gamba, D; Pelliccioni, M; Bomben, M; Bosisio, L; Cartaro, C; Della Ricca, G; Lanceri, L; Vitale, L; Azzolini, V; Lopez-March, N; Martinez-Vidal, F; Milanes, D A; Oyanguren, A; Albert, J; Banerjee, Sw; Bhuyan, B; Choi, H H F; Hamano, K; Kowalewski, R; Lewczuk, M J; Nugent, I M; Roney, J M; Sobie, R J; Gershon, T J; Harrison, P F; Ilic, J; Latham, T E; Mohanty, G B; Band, H R; Chen, X; Dasu, S; Flood, K T; Pan, Y; Pierini, M; Prepost, R; Vuosalo, C O; Wu, S L

2008-12-31

We report a measurement of the branching fractions of B-->D**(l) nu(l), decays based on 417 fb(-1) of data collected at the Y(4S) resonance with the BABAR detector at the PEP-II e+e- storage rings. Events are selected by full reconstructing one of the B mesons in a hadronic decay mode. A fit to the invariant mass differences m(D(*) pi)- m(D(*)) is performed to extract the signal yields of the different D** states. We observe the B-->D**l(-1)nu(l) decay modes corresponding to the four D states predicted by heavy quark symmetry with a significance greater than 5 standard deviations including systematic uncertainties.

Excited meson spectroscopy with two chirally improved quarks

NASA Astrophysics Data System (ADS)

Engel, G.; Lang, C. B.; Mohler, D.; Limmer, M.; Schäfer, A.

The excited isovector meson spectrum is explored using two chirally improved dynamical quarks. Seven ensembles, with pion masses down to \\approx 250 MeV are discussed and used for extrapolations to the physical point. Strange mesons are investigated using partially quenched s-quarks. Using the variational method, we extract excited states in several channels and most of the results are in good agreement with experiment.

On the possibility of thermalization of heavy mesons in ultrarelativistic nuclear collisions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lokhtin, I. P., E-mail: Igor.Lokhtin@cern.ch; Belyaev, A. V.; Ponimatkin, G.

2017-02-15

The phenomenological analysis and interpretation of experimental data from RHIC and LHC on the production of J/ψ and D mesons in heavy-ion collisions are performed within the two-component HYDJET++ model including the thermal and hard mechanisms of hadron production. It is shown that the thermal freeze-out of charmed mesons at RHIC energies occurs earlier than the thermal freeze-out of light hadrons (assumingly, simultaneously with chemical freeze-out), which indicates that J/ψ and D mesons are not in kinetic equilibrium with the formed hadronic matter. At the same time, a significant part of D mesons at LHC energies are in kinetic equilibriummore » with the formed thermalized matter, but J/ψ mesons are still characterized by early freeze-out.« less

Study of the Rare Decay B Mesons Decaying to X Mesons Positive And Negative Leptons at BABAR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koptchev, Ventzislav B.; /Massachusetts U., Amherst

2005-08-30

Flavor-changing neutral current transitions are forbidden at tree level in the Standard Model and can only occur via higher order diagrams. Since the amplitudes for such loops are dominated by the heaviest known particles, and non-SM effects are expected to contribute at the same order as the SM, such processes are an ideal place to look for new physics. We present a measurement of the inclusive branching fraction for the flavor-changing neutral current process B {yields} X{sub s}{ell}{sup +}{ell}{sup -} with a sample of 81.9 fb{sup -1}, collected with the BABAR detector at the Stanford Linear Accelerator Center. The finalmore » state is reconstructed from e{sup +}e{sup -} or {mu}{sup +}{mu}{sup -} pairs and a hadronic system consisting of one K{sup {+-}} or K{sub s} and up to two pions, with at most one {pi}{sup 0}. They observe a signal of 40 {+-} 10(stat) {+-} 2(syst) events and extract a branching fraction {Beta}(B {yields} X{sub s}{ell}{sup +}{ell}{sup -}) = (5.6 {+-} 1.5(stat) {+-} 0.6(exp. syst) {+-} 1.1(model syst)) x 10{sup -6} for m{sub ll} > 0.2 GeV.« less

Effects of renormalizing the chiral SU(2) quark-meson model

NASA Astrophysics Data System (ADS)

Zacchi, Andreas; Schaffner-Bielich, Jürgen

2018-04-01

We investigate the restoration of chiral symmetry at finite temperature in the SU(2) quark-meson model, where the mean field approximation is compared to the renormalized version for quarks and mesons. In a combined approach at finite temperature, all the renormalized versions show a crossover transition. The inclusion of different renormalization scales leave the order parameter and the mass spectra nearly untouched but strongly influence the thermodynamics at low temperatures and around the phase transition. We find unphysical results for the renormalized version of mesons and the combined one.

Chiral symmetry breaking and the spin content of the ρ and ρ‧ mesons

NASA Astrophysics Data System (ADS)

Glozman, L. Ya.; Lang, C. B.; Limmer, M.

2011-11-01

Using interpolators with different SU(2)L × SU(2)R transformation properties we study the chiral symmetry and spin contents of the ρ and ρ‧ mesons in lattice simulations with dynamical quarks. A ratio of couplings of the qbarγi τq and qbarσ0i τq interpolators to a given meson state at different resolution scales tells one about the degree of chiral symmetry breaking in the meson wave function at these scales. Using a Gaussian gauge invariant smearing of the quark fields in the interpolators, we are able to extract the chiral content of mesons up to the infrared resolution of ∼ 1 fm. In the ground state ρ meson the chiral symmetry is strongly broken with comparable contributions of both the (0 , 1) + (1 , 0) and (1 / 2 , 1 / 2) b chiral representations with the former being the leading contribution. In contrast, in the ρ‧ meson the degree of chiral symmetry breaking is manifestly smaller and the leading representation is (1 / 2 , 1 / 2) b. Using a unitary transformation from the chiral basis to the LJ2S+1 basis, we are able to define and measure the angular momentum content of mesons in the rest frame. This definition is different from the traditional one which uses parton distributions in the infinite momentum frame. The ρ meson is practically a 3S1 state with no obvious trace of a "spin crisis". The ρ‧ meson has a sizeable contribution of the 3D1 wave, which implies that the ρ‧ meson cannot be considered as a pure radial excitation of the ρ meson.

Celestial diffuse gamma radiation above 30 MeV observed by SAS-2

NASA Technical Reports Server (NTRS)

Fichtel, C. E.; Kniffen, D. A.; Hartman, R. C.

1973-01-01

The Small Astronomy Satellite (SAS)-2, launched on November 15, 1972, carried into orbit a 32-deck magnetic-core digitized spark chamber gamma ray telescope to study celestial gamma radiation in the energy range above 30 MeV. In the study of several regions with b sub 2 15 deg, a finite, diffuse flux of gamma rays with a steep energy spectrum in the energy region from 35 to 200 MeV is observed. Representing the energy spectrum by a power law of the form dJ/dE = AE to - alpha power over this energy range, alpha is found along with the integral flux above 100 MeV. Combining this result with existing low energy gamma ray data yields an energy spectrum which is not a simple power law in energy, as in the X-ray region, but which demonstrates first an increase and then a decrease in slope, consistent within uncertainties with that predicted by cosmological theories, including the continuous production of high energy gamma rays primarily from neutral pi mesons throughout the history of the universe.

Ab initio calculation of the $$np \\to d ³$$ radiative capture process

DOE PAGES

Beane, Silas R.; Chang, Emmanuel; Detmold, William; ...

2015-09-24

In this study, lattice QCD calculations of two-nucleon systems are used to isolate the short-distance two-body electromagnetic contributions to the radiative capture processmore » $$np \\to d\\gamma$$, and the photo-disintegration processes $$\\gamma^{(\\ast)} d \\to np$$. In nuclear potential models, such contributions are described by phenomenological meson-exchange currents, while in the present work, they are determined directly from the quark and gluon interactions of QCD. Calculations of neutron-proton energy levels in multiple background magnetic fields are performed at two values of the quark masses, corresponding to pion masses of $$m_\\pi \\sim 450$$ and 806 MeV, and are combined with pionless nuclear effective field theory to determine these low-energy inelastic processes. Extrapolating to the physical pion mass, a cross section of $$\\sigma^{lqcd}(np\\to d\\gamma)=332.4({\\tiny \\begin{array}{l}+5.4 \\\\ - 4.7\\end{array}})\\ mb$$ is obtained at an incident neutron speed of $$v=2,200\\ m/s$$, consistent with the experimental value of $$\\sigma^{expt}(np \\to d\\gamma) = 334.2(0.5)\\ mb$$.« less

Performance of PI-RADS version 1 versus version 2 regarding the relation with histopathological results.

PubMed

Auer, Thomas; Edlinger, Michael; Bektic, Jasmin; Nagele, Udo; Herrmann, Thomas; Schäfer, Georg; Aigner, Friedrich; Junker, Daniel

2017-05-01

Aim of this study was to compare the diagnostic performance of PI-RADS version 1 (v1) and version 2 (v2) in the detection of prostate cancer (PCa). Multiparametric MRIs (mpMRI) of 50 consecutive patients with biopsy proven PCa, which had originally been evaluated according to PIRADS v1, were now retrospectively re-evaluated, comparing PI-RADS v1 and v2. MpMRI data were evaluated in comparison with histopathological whole-mount step-section slides. MRI examinations included T2-weighted, diffusion-weighted, and dynamic contrast-enhanced MRI. Overall PI-RADS v1 showed a significantly larger discriminative ability of tumor detection: PI-RADS v1 AUC 0.96 (95 % CI 0.94-0.98) and v2 AUC 0.90 (95 % CI 0.86-0.94). For peripheral zone lesions, PI-RADS v1 showed a significantly larger ability of PCa discrimination: v1 AUC 0.97 (95 % CI 0.95-0.99) and v2 AUC 0.92 (95 % CI 0.88-0.96). For transition zone lesions, PI-RADS v1 showed more discrimination: v1 AUC 0.96 (95 % CI 0.92-1.00) and v2 0.90 (95 % CI 0.83-0.97), but the difference was not significant. PI-RADS v2 resulted in significantly more false negative results (3 % in v1, 14 % in v2) and a comparable number of true positive results (82 % in v1, 80 % in v2). PI-RADS v2 uses a simplified approach, but shows a lower diagnostic accuracy. This could lead to a higher rate of false negative results with the risk of missing tumors within low PI-RADS score levels. Therefore, its use cannot be recommended unconditionally, and further improvement should be considered.

Comparison of D--> KS0 pi and D--> KL0 pi decay rates.

PubMed

He, Q; Insler, J; Muramatsu, H; Park, C S; Thorndike, E H; Yang, F; Coan, T E; Gao, Y S; Artuso, M; Blusk, S; Butt, J; Li, J; Menaa, N; Mountain, R; Nisar, S; Randrianarivony, K; Sia, R; Skwarnicki, T; Stone, S; Wang, J C; Zhang, K; Bonvicini, G; Cinabro, D; Dubrovin, M; Lincoln, A; Asner, D M; Edwards, K W; Briere, R A; Ferguson, T; Tatishvili, G; Vogel, H; Watkins, M E; Rosner, J L; Adam, N E; Alexander, J P; Cassel, D G; Duboscq, J E; Ehrlich, R; Fields, L; Gibbons, L; Gray, R; Gray, S W; Hartill, D L; Heltsley, B K; Hertz, D; Jones, C D; Kandaswamy, J; Kreinick, D L; Kuznetsov, V E; Mahlke-Krüger, H; Onyisi, P U E; Patterson, J R; Peterson, D; Pivarski, J; Riley, D; Ryd, A; Sadoff, A J; Schwarthoff, H; Shi, X; Stroiney, S; Sun, W M; Wilksen, T; Weinberger, M; Athar, S B; Patel, R; Potlia, V; Yelton, J; Rubin, P; Cawlfield, C; Eisenstein, B I; Karliner, I; Kim, D; Lowrey, N; Naik, P; Selen, M; White, E J; Wiss, J; Mitchell, R E; Shepherd, M R; Besson, D; Pedlar, T K; Cronin-Hennessy, D; Gao, K Y; Hietala, J; Kubota, Y; Klein, T; Lang, B W; Poling, R; Scott, A W; Smith, A; Zweber, P; Dobbs, S; Metreveli, Z; Seth, K K; Tomaradze, A; Ernst, J; Ecklund, K M; Severini, H; Love, W; Savinov, V; Aquines, O; Li, Z; Lopez, A; Mehrabyan, S; Mendez, H; Ramirez, J; Huang, G S; Miller, D H; Pavlunin, V; Sanghi, B; Shipsey, I P J; Xin, B; Adams, G S; Anderson, M; Cummings, J P; Danko, I; Hu, D; Moziak, B; Napolitano, J

2008-03-07

We present measurements of D--> KS0 pi and D--> KL0 pi branching fractions using 281 pb(-1) of psi(3770) data at the CLEO-c experiment. We find that B(D0--> KS0 pi 0) is larger than B(D0--> KL0 pi 0), with an asymmetry of R(D0)=0.108+/-0.025+/-0.024. For B(D+--> KS0 pi+) and B(D+--> KL0 pi+), we observe no measurable difference; the asymmetry is R(D+)=0.022+/-0.016+/-0.018. The D0 asymmetry is consistent with the value based on the U-spin prediction A(D0--> K0 pi 0)/A(D0--> K0 pi 0)=-tan2 theta C, where theta C is the Cabibbo angle.

Vector meson photoproduction with a linearly polarized beam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mathieu, V.; Nys, J.; Fernendez-Ramirez, C.

Here, we propose a model based on Regge theory to describe photoproduction of light vector mesons. We fit the SLAC data and make predictions for the energy and momentum transfer dependence of the spin-density matrix elements in photoproduction of ω,more » $$\\rho^0$$ and $$\\sigma$$ mesons at Ε γ ~ 8.5 GeV, which are soon to be measured at Jefferson Lab.« less

Vector meson photoproduction with a linearly polarized beam

DOE PAGES

Mathieu, V.; Nys, J.; Fernendez-Ramirez, C.; ...

2018-05-09

Here, we propose a model based on Regge theory to describe photoproduction of light vector mesons. We fit the SLAC data and make predictions for the energy and momentum transfer dependence of the spin-density matrix elements in photoproduction of ω,more » $$\\rho^0$$ and $$\\sigma$$ mesons at Ε γ ~ 8.5 GeV, which are soon to be measured at Jefferson Lab.« less

Elliptic flow of ϕ mesons at intermediate pT: Influence of mass versus quark number

NASA Astrophysics Data System (ADS)

Choudhury, Subikash; Sarkar, Debojit; Chattopadhyay, Subhasis

2017-02-01

We have studied elliptic flow (v2) of ϕ mesons in the framework of a multiphase transport (AMPT) model at CERN Large Hadron Collider (LHC) energy. In the realms of AMPT model we observe that ϕ mesons at intermediate transverse momentum (pT) deviate from the previously observed [at the BNL Relativistic Heavy Ion Collider (RHIC)] particle type grouping of v2 according to the number of quark content, i.e, baryons and mesons. Recent results from the ALICE Collaboration have shown that ϕ meson and proton v2 has a similar trend, possibly indicating that particle type grouping might be due to the mass of the particles and not the quark content. A stronger radial boost at LHC compared to RHIC seems to offer a consistent explanation to such observation. However, recalling that ϕ mesons decouple from the hadronic medium before additional radial flow is built up in the hadronic phase, a similar pattern in ϕ meson and proton v2 may not be due to radial flow alone. Our study reveals that models incorporating ϕ -meson production from K K ¯ fusion in the hadronic rescattering phase also predict a comparable magnitude of ϕ meson and proton v2 particularly in the intermediate region of pT. Whereas, v2 of ϕ mesons created in the partonic phase is in agreement with quark-coalescence motivated baryon-meson grouping of hadron v2. This observation seems to provide a plausible alternative interpretation for the apparent mass-like behavior of ϕ -meson v2. We have also observed a violation of hydrodynamical mass ordering between proton and ϕ meson v2 further supporting that ϕ mesons are negligibly affected by the collective radial flow in the hadronic phase due to the small in-medium hadronic interaction cross sections.

A-dependence of phi meson production at HERA-B

NASA Astrophysics Data System (ADS)

Ispiryan, Mikayel

In the HERA-B experiment at DESY, Germany, 920 GeV protons collide with nuclei of the targets. In the collisions many hadrons are produced and detected by the spectrometer, allowing the study of various issues of hadron-hadron and hadron-nucleus interactions. In this thesis the production dependence of the φ meson on the atomic weight A of the nuclei has been studied for several materials, with the goal of obtaining experimental information on proton-nucleus (p-A) interactions. For this, runs and events have been selected according to special criteria. The φ meson's signature---its decay into two charged kaons---has been used to detect the fact of the production of a φ meson in the collision. The RICH detector, the tracking system, and selection algorithms have been used for identification of kaons. The main result, obtaining of which does not depend on the knowledge of integrated luminosity and does not depend heavily on the Monte Carlo simulation of the spectrometer, is the exponent Deltaalpha of the power law of the φ meson production cross-section in an inelastic interaction: sigma ∝ ADeltaalpha, which was measured to be 0.14 .. 0.19 for tungsten, titanium and rhenium, with Deltaalpha = 0.141 +/- 0.012(stat) +/- 0.022(sys) being the most exact number obtained from the analysis of ˜108 events on carbon and tungsten targets. As a by-product, the mass of the φ meson is obtained to be 1.01957 GeV, which did not show dependence on the type of the target nucleus within statistical error of approximately +/-80 keV. The results show a clear experimental indication of A-dependence for φ meson production in proton-nucleon inelastic interactions.

Natural variation of piRNA expression affects immunity to transposable elements.

PubMed

Ryazansky, Sergei; Radion, Elizaveta; Mironova, Anastasia; Akulenko, Natalia; Abramov, Yuri; Morgunova, Valeriya; Kordyukova, Maria Y; Olovnikov, Ivan; Kalmykova, Alla

2017-04-01

In the Drosophila germline, transposable elements (TEs) are silenced by PIWI-interacting RNA (piRNA) that originate from distinct genomic regions termed piRNA clusters and are processed by PIWI-subfamily Argonaute proteins. Here, we explore the variation in the ability to restrain an alien TE in different Drosophila strains. The I-element is a retrotransposon involved in the phenomenon of I-R hybrid dysgenesis in Drosophila melanogaster. Genomes of R strains do not contain active I-elements, but harbour remnants of ancestral I-related elements. The permissivity to I-element activity of R females, called reactivity, varies considerably in natural R populations, indicating the existence of a strong natural polymorphism in defense systems targeting transposons. To reveal the nature of such polymorphisms, we compared ovarian small RNAs between R strains with low and high reactivity and show that reactivity negatively correlates with the ancestral I-element-specific piRNA content. Analysis of piRNA clusters containing remnants of I-elements shows increased expression of the piRNA precursors and enrichment by the Heterochromatin Protein 1 homolog, Rhino, in weak R strains, which is in accordance with stronger piRNA expression by these regions. To explore the nature of the differences in piRNA production, we focused on two R strains, weak and strong, and showed that the efficiency of maternal inheritance of piRNAs as well as the I-element copy number are very similar in both strains. At the same time, germline and somatic uni-strand piRNA clusters generate more piRNAs in strains with low reactivity, suggesting the relationship between the efficiency of primary piRNA production and variable response to TE invasions. The strength of adaptive genome defense is likely driven by naturally occurring polymorphisms in the rapidly evolving piRNA pathway proteins. We hypothesize that hyper-efficient piRNA production is contributing to elimination of a telomeric retrotransposon He

Conversion of phosphatidylinositol (PI) to PI4-phosphate (PI4P) and then to PI(4,5)P2 is essential for the cytosolic Ca2+ concentration under heat stress in Ganoderma lucidum.

PubMed

Liu, Yong-Nan; Lu, Xiao-Xiao; Ren, Ang; Shi, Liang; Zhu, Jing; Jiang, Ai-Liang; Yu, Han-Shou; Zhao, Ming-Wen

2018-04-26

How cells drive the phospholipid signal response to heat stress (HS) to maintain cellular homeostasis is a fundamental issue in biology, but the regulatory mechanism of this fundamental process is unclear. Previous quantitative analyses of lipids showed that phosphatidylinositol (PI) accumulates after HS in Ganoderma lucidum, implying the inositol phospholipid signal may be associated with HS signal transduction. Here, we found that the PI-4-kinase and PI-4-phosphate-5-kinase activities are activated and that their lipid products PI-4-phosphate and PI-4,5-bisphosphate are increased under HS. Further experimental results showed that the cytosolic Ca 2+ ([Ca 2+ ] c ) and ganoderic acid (GA) contents induced by HS were decreased when cells were pretreated with Li + , an inhibitor of inositol monophosphatase, and this decrease could be rescued by PI and PI-4-phosphate. Furthermore, inhibition of PI-4-kinases resulted in a decrease in the Ca 2+ and GA contents under HS that could be rescued by PI-4-phosphate but not PI. However, the decrease in the Ca 2+ and GA contents by silencing of PI-4-phosphate-5-kinase could not be rescued by PI-4-phosphate. Taken together, our study reveals the essential role of the step converting PI to PI-4-phosphate and then to PI-4,5-bisphosphate in [Ca 2+ ] c signalling and GA biosynthesis under HS. © 2018 Society for Applied Microbiology and John Wiley & Sons Ltd.

Light Meson Decays at BESIII

NASA Astrophysics Data System (ADS)

Fang, Shuangshi

2017-04-01

At present the world's largest sample of 1.3 billion J/ψ events was accumulated at the BESIII detector, which offers a unique place to study light meson decays. The recent results on the light meson decays are reviewed in this talk. An emphasis is put on the significant progresses on the study of η/η' decays, including Dalitz plot analysis of η/η' → πππ, observation of new decay modes (η' → π+π-π+(0)π-(0), η' → ρ±π∓, η' → γe+e- and η' → e+e-ω), study of η' → γπ+π- and search for the rare decay of η' → Kπ. In addition, a prospect on the Dalitz plot analysis of ω → π+π-π0 is presented.

Meson properties in asymmetric matter

NASA Astrophysics Data System (ADS)

Mammarella, Andrea; Mannarelli, Massimo

2018-03-01

In this work we study dynamic and thermodynamic (at T = 0) properties of mesons in asymmetric matter in the framework of Chiral Perturbation Theory. We consider a system at vanishing temperature with nonzero isospin chemical potential and strangeness chemical potential; meson masses and mixing in the normal phase, the pion condensation phase and the kaon condensation phase are described. We find differences with previous works, but the results presented here are supported by both theory group analysis and by direct calculations. Some pion decay channels in the normal and the pion condensation phases are studied, finding a nonmonotonic behavior of the decay width as a function of µ I . Furthermore, pressure, density and equation of state of the system at T = 0 are studied, finding remarkable agreement with analogue studies performed by lattice calculations.

Angular Momentum Content of the ρ Meson in Lattice QCD

NASA Astrophysics Data System (ADS)

Glozman, Leonid Ya.; Lang, C. B.; Limmer, Markus

2009-09-01

The variational method allows one to study the mixing of interpolators with different chiral transformation properties in the nonperturbatively determined physical state. It is then possible to define and calculate in a gauge-invariant manner the chiral as well as the partial wave content of the quark-antiquark component of a meson in the infrared, where mass is generated. Using a unitary transformation from the chiral basis to the LJ2S+1 basis one may extract a partial wave content of a meson. We present results for the ground state of the ρ meson using quenched simulations as well as simulations with nf=2 dynamical quarks, all for lattice spacings close to 0.15 fm. We point out that these results indicate a simple S13-wave composition of the ρ meson in the infrared, like in the SU(6) flavor-spin quark model.

Angular momentum content of the rho meson in lattice QCD.

PubMed

Glozman, Leonid Ya; Lang, C B; Limmer, Markus

2009-09-18

The variational method allows one to study the mixing of interpolators with different chiral transformation properties in the nonperturbatively determined physical state. It is then possible to define and calculate in a gauge-invariant manner the chiral as well as the partial wave content of the quark-antiquark component of a meson in the infrared, where mass is generated. Using a unitary transformation from the chiral basis to the ;{2S+1}L_{J} basis one may extract a partial wave content of a meson. We present results for the ground state of the rho meson using quenched simulations as well as simulations with n_{f} = 2 dynamical quarks, all for lattice spacings close to 0.15 fm. We point out that these results indicate a simple ;{3}S_{1}-wave composition of the rho meson in the infrared, like in the SU(6) flavor-spin quark model.

Resonances in the predissociation of the A{sup 2}{Pi}{sub {Omega}} state of MgBr

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sadygov, R.G.; Rostas, J.; Taieb, G.

1997-03-01

Electronic structure methods and nonperturbative resonance theory are applied to study the radiative and radiationless decay mechanisms of the MgBr (A{sup 2}{Pi}{sub {Omega}}) vibrational levels. The X{sup 2}{Sigma}{sup +} and 1,2{sup 2}{Pi}{sub {Omega}} adiabatic electronic states are characterized using {ital ab initio} state-averaged multiconfigurational self-consistent field/second order configuration interaction wave functions. Interstate derivative couplings between the {sup 2}{Pi} states have been calculated and used to construct a rigorous diabatic basis. The nonrelativistic potential energy curves are modified in the first order of degenerate perturbation theory to take account of the spin{endash}orbit interactions treated within Breit{endash}Pauli approximation. All vibrational levels inmore » the A{sup 2}{Pi}{sub {Omega}} manifold are resonances predissociated by the repulsive 2{sup 2}{Pi} state. A recently developed computational approach [S. Han and D. R. Yarkony, Mol. Phys. {bold 88}, 53 (1996)] based on a Feshbach formalism is employed to determine energies, linewidths, and radiative and radiationless decay rates in a coupled diabatic states basis within a Hund`s case (a) approximation. Large nonadiabatic interactions cause significant energy shifts in the resonances levels. It is shown that a pronounced {Omega}-dependence in the radiationless decay rates results from the large fine structure splitting in the 2{sup 2}{Pi}{sub {Omega}} diabatic state which corresponds to Mg({sup 1}S)Br({sup 2}P). Comparisons with absorption and fluorescence spectra reveal important insights into A{sup 2}{Pi}{sub {Omega}} state decay. The spectroscopic constants of the A{sup 2}{Pi}{sub {Omega}}, {Omega}=3/2 and 1/2 states and the A{sup 2}{Pi}{sub 3/2} state predissociation are well described in a Hund`s case (a) approximation. However it is found that the A{sup 2}{Pi}{sub 1/2} state predissociation is significantly underestimated in this limit. (Abstract Truncated)« less

Spermatozoa Expression of piR-31704, piR-39888, and piR-40349 and Their Correlation to Sperm Concentration and Fertilization Rate After ICSI.

PubMed

Cui, Long; Fang, Li; Shi, Biwei; Qiu, Sunquan; Ye, Yinghui

2018-05-01

To investigate the relationship between spermatozoa PIWI-interacting RNAs (piRNAs) levels and semen parameters and to evaluate the role of expression of piRNAs on fertilization and embryo development after intracytoplasmic sperm injection (ICSI) treatment. One hundred and eighty-six patients with idiopathic male infertility who had undergone first ICSI cycles were enrolled in our study. The levels of piRNAs in spermatozoa were measured by real-time polymerase chain reaction. Semen parameters, including sperm concentration, motility, and morphology, were evaluated. The rates of fertilization, early cleavage, and day 3 good-quality embryo were calculated to assess embryo development potential. Spermatozoa levels of piR-31704 and piR-39888 were decreased in male factor infertility group as compared with control group (for piR-31704, P = .027 and for piR-39888, P = .041, respectively). And these 2 piRNAs were expressed at higher levels in patients with normal sperm concentration compared with subnormal sperm concentration group (for piR-31704, P = .042; for piR-39888, P = .047, respectively), while there were no correlation between the 3 piRNAs expression levels in spermatozoa and the rates of sperm progressive motility and normal sperm morphology. There were significant increases in the levels of all 3 piRNAs in spermatozoa from the group with higher 2PN rates (for piR-31704, P = .002; for piR-39888, P < .001; for piR-40349, P < .001; respectively), but there was no correlation between spermatozoa levels of these 3 piRNAs and the rates of embryo early cleavage, day 3 good-quality embryos and pregnancy. Spermatozoa piRNA levels correlate with sperm concentration and fertilization rate after ICSI. Paternal piRNAs may play a role in fertilization process.

Amplitude Analysis of B0 to K^ pi^-pi^0 and Evidence of Direct CP Violation in B to K^* pi decays

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lees, J.P.

We analyze the decay B{sup 0} {yields} K{sup +} {pi}{sup -} {pi}{sup 0} with a sample of 454 million B{bar B} events collected by the BABAR detector at the PEP-II asymmetric-energy B factory at SLAC, and extract the complex amplitudes of seven interfering resonances over the Dalitz plot. These results are combined with amplitudes measured in B{sup 0} {yields} K{sup 0}{sub s}{pi}{sup +}{pi}{sup -} decays to construct isospin amplitudes from B{sup 0} {yields} K{sup *}{pi} and B{sup 0} {yields} {rho}K decays. We measure the phase of the isospin amplitude {Phi}{sub 3/2}, useful in constraining the CKM unitarity triangle angle {gamma}more » and evaluate a CP rate asymmetry sum rule sensitive to the presence of new physics operators. We measure direct CP violation in B{sup 0} {yields} K{sup *+}{pi}{sup -} decays at the level of 3 {sigma} when measurements from both B{sup 0} {yields} K{sup +}{pi}{sup -}{pi}{sup 0} and B{sup 0} {yields} K{sup 0}{sub s}{pi}{sup +}{pi}{sup -} decays are combined.« less

Tree regeneration following drought- and insect-induced mortality in piñon-juniper woodlands.

PubMed

Redmond, Miranda D; Barger, Nichole N

2013-10-01

Widespread piñon (Pinus edulis) mortality occurred across the southwestern USA during 2002-2003 in response to drought and bark beetle infestations. Given the recent mortality and changes in regional climate over the past several decades, there is a keen interest in post-mortality regeneration dynamics in piñon-juniper woodlands. Here, we examined piñon and Utah juniper (Juniperus osteosperma) recruitment at 30 sites across southwestern Colorado, USA that spanned a gradient of adult piñon mortality levels (10-100%) to understand current regeneration dynamics. Piñon and juniper recruitment was greater at sites with more tree and shrub cover. Piñon recruitment was more strongly facilitated than juniper recruitment by trees and shrubs. New (post-mortality) piñon recruitment was negatively affected by recent mortality. However, mortality had no effect on piñon advanced regeneration (juveniles established pre-mortality) and did not shift juvenile piñon dominance. Our results highlight the importance of shrubs and juniper trees for the facilitation of piñon establishment and survival. Regardless of adult piñon mortality levels, areas with low tree and shrub cover may become increasingly juniper dominated as a result of the few suitable microsites for piñon establishment and survival. In areas with high piñon mortality and high tree and shrub cover, our results suggest that piñon is regenerating via advanced regeneration. © 2013 The Authors. New Phytologist © 2013 New Phytologist Trust.

Scattering phaseshift formulas for mesons and baryons in elongated boxes

NASA Astrophysics Data System (ADS)

Lee, Frank X.; Alexandru, Andrei

2018-03-01

We derive Lüscher phaseshift formulas for two-particle states in boxes elongated in one of the dimensions. Such boxes offer a cost-effective way of varying the relative momentum of the particles. Boosted states in the elongated direction, which allow wider access to energies, are also considered. The formulas for the various scenarios (moving and zero-momentum states in cubic and elongated boxes) are compared and relations between them are clarified. The results are applicable to a wide set of meson-meson and meson-baryon elastic scattering processes, with the two-particle system having equal or unequal masses.

Beauty vector meson decay constants from QCD sum rules

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lucha, Wolfgang; Melikhov, Dmitri; D. V. Skobeltsyn Institute of Nuclear Physics, M. V. Lomonosov Moscow State University, 119991, Moscow

We present the outcomes of a very recent investigation of the decay constants of nonstrange and strange heavy-light beauty vector mesons, with special emphasis on the ratio of any such decay constant to the decay constant of the corresponding pseudoscalar meson, by means of Borel-transformed QCD sum rules. Our results suggest that both these ratios are below unity.

Superconformal Baryon-Meson Symmetry and Light-Front Holographic QCD

DOE PAGES

Dosch, Hans Guenter; de Teramond, Guy F.; Brodsky, Stanley J.

2015-04-10

We construct an effective QCD light-front Hamiltonian for both mesons and baryons in the chiral limit based on the generalized supercharges of a superconformal graded algebra. The superconformal construction is shown to be equivalent to a semi-classical approximation to light-front QCD and its embedding in AdS space. The specific breaking of conformal invariance inside the graded algebra uniquely determines the effective confinement potential. The generalized supercharges connect the baryon and meson spectra to each other in a remarkable manner. In particular, the π/b 1 Regge trajectory is identified as the superpartner of the nucleon trajectory. However, the lowest-lying state onmore » this trajectory, the π-meson is massless in the chiral limit and has no supersymmetric partner.« less

The Story of PI

NASA Technical Reports Server (NTRS)

Apostol, Tom M. (Editor)

1989-01-01

The early history and the uses of the mathematical notation - pi - are presented through both film footage and computer animation in this 'Project Mathematics' series video. Pi comes from the first letter in the Greek word for perimeter. Archimedes, and early Greek mathematician, formulated the equations for the computation of a circle's area using pi and was the first person to seriously approximate pi numerically, although only to a few decimal places. By 1985, pi had been approximated to over one billion decimal places and was found to have no repeating pattern. One use of pi is the application of its approximation calculation as an analytical tool for determining the accuracy of supercomputers and software designs.

Search for resonances decaying to etac pi pi- in two-photon interactions

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lees, J.P.; Poireau, V.; Tisserand, V.

2012-06-18

We report a study of the process {gamma}{gamma} {yields} X {yields} {eta}{sub c}{pi}{sup +}{pi}{sup -}, where X stands for one of the resonances {chi}{sub c2}(1P), {eta}{sub c}(2S), X(3872), X(3915), or {chi}{sub c2}(2P). The analysis is performed with a data sample of 473.9 fb{sup -1} collected with the BABAR detector at the PEP-II asymmetric-energy electron-positron collider. We do not observe a significant signal for any channel, and calculate 90% confidence-level upper limits on the products of branching fractions and two-photon widths {Lambda}{sub X{yields}{gamma}{gamma}} {Beta}(X {yields} {eta}{sub c}{pi}{sup +}{pi}{sup -}): 15.7 eV for {chi}{sub c2}(1P), 133 eV for {eta}{sub c}(2S), 11.1 eVmore » for X(3872) (assuming it to be a spin-2 state), 16 eV for X(3915) (assuming it to be a spin-2 state), and 19 eV for {chi}{sub c2}(2P). We also report upper limits on the ratios of branching fractions {Beta}({eta}{sub c}(2S) {yields} {eta}{sub c}{pi}{sup +}{pi}{sup -})/{Beta}({eta}{sub c}(2S) {yields} K{sub S}{sup 0}K{sup +}{pi}{sup -}) < 10.0 and {Beta}({chi}{sub c2}(1P) {yields} {eta}{sub c}{pi}{sup +}{pi}{sup -})/{Beta}({chi}{sub c2}(1P) {yields} K{sub S}{sup 0}K{sup +}{pi}{sup -}) < 32.9 at the 90% confidence level.« less

Measurement of the K- pi+ S-wave system in D+ ---> K- pi+ pi+ decays from Fermilab E791

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meadows, B.; /Cincinnati U.

A new approach to the analysis of three body decays is presented. Measurements of the S-wave K{pi} amplitude are made in independent ranges of invariant mass from threshold up to the upper kinematic limit in D{sup +} {yields} K{sup -}{pi}{sup +}{pi}{sup +} decays. These are compared with results obtained from a fit where the S-wave is assumed to have {kappa} and K{sub 0}{sup +}(1430) resonances. Results are also compared with measurements of K{sup -} {pi}{sup +} elastic scattering. Contributions from I = 1/2 and I = 3/2 are not resolved in this study. If I = 1/2 dominates, however, themore » Watson theorem prediction, that the phase behavior below K{eta}' threshold should match that in elastic scattering, is not well supported by these data. Production of K{sup -} {pi}{sup +} from these D decays is also studied.« less

Study of the Rare Hyperon Decay $${\\boldmath \\Omega^\\mp \\to \\Xi^\\mp \\: \\pi^+\\pi^-}$$

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kamaev, O.; Solomey, N.; Burnstein, R.A.

The authors report a new measurement of the decay {Omega}{sup -} {yields} {Xi}{sup -} {pi}{sup +}{pi}{sup -} with 76 events and a first observation of the decay {bar {Omega}}{sup +} {yields} {bar {Xi}}{sup +} {pi}{sup +}{pi}{sup -} with 24 events, yielding a combined branching ratio (3.74{sub -0.56}{sup +0.67}) x 10{sup -4}. This represents a factor 25 increase in statistics over the best previous measurement. No evidence is seen for CP violation, with {Beta}({Omega}{sup -} {yields} {Xi}{sup -} {pi}{sup +}{pi}{sup -}) = 4.04{sub -0.71}{sup +0.83} x 10{sup -4} and {Beta}({bar {Omega}}{sup +} {yields} {bar {Xi}}{sup +} {pi}{sup +}{pi}{sup -}) = 3.15{submore » -0.89}{sup +1.12} x 10{sup -4}. Contrary to theoretical expectation, they see little evidence for the decays {Omega}{sup -} {yields} {Xi}*{sub 1530}{sup 0} {pi}{sup -} and {bar {Omega}}{sup +} {yields} {bar {Xi}}*{sub 1530}{sup 0} {pi}{sup +} and place a 90% C.L. upper limit on the combined branching ratio {Beta}({Omega}{sup -}({bar {Omega}}{sup +}) {yields} {Xi}*{sub 1530}{sup 0} ({bar {Xi}}*{sub 1530}{sup 0}){pi}{sup {-+}}) < 7.0 x 10{sup -5}.« less

Radiative Penguin Decays at the B Factories

DOE Office of Scientific and Technical Information (OSTI.GOV)

Koneke, Karsten; /MIT, LNS

2007-11-16

In this article, I review the most recent results in radiative penguin decays from the B factories Belle and BABAR. Most notably, I will talk about the recent new observations in the decays B {yields} ({rho}/{omega}) {gamma}, a new analysis technique in b {yields} s{gamma}, and first measurements of radiative penguin decays in the B{sup 0}{sub s} meson system. Finally, I will summarize the current status and future prospects of radiative penguin B physics at the B factories.

The radiative decay {{\\rm{D}}}^{{\\rm{0}}}\\to {\\bar{{\\rm{K}}}}^{{\\rm{* 0}}}\\gamma with vector meson dominance

NASA Astrophysics Data System (ADS)

Dias, J. M.; Debastiani, V. R.; Xie, Ju-Jun; Oset, E.

2018-04-01

Motivated by the experimental measurements of D0 radiative decay modes, we have proposed a model to study the {{{D}}}{{0}}\\to {\\bar{{{K}}}}{{* 0}}γ decay, by establishing a link with {{{D}}}{{0}}\\to {\\bar{{{K}}}}{{* 0}}{{V}} (V=ρ0, ω) decays through the vector meson dominance hypothesis. In order to do this properly, we have used the Lagrangians from the local hidden gauge symmetry approach to account for Vγ conversion. As a result, we have found the branching ratio {\\mathcal B} [{{{D}}}{{0}}\\to { \\bar{{{K}}}}{{* 0}}γ ]{{=}}({{1}}.{{55-3}}.{{44}})× {{{10}}}{{-4}}, which is in fair agreement with the experimental values reported by the Belle and BaBar collaborations. J. M. Dias would like to thank the Brazilian funding agency FAPESP for the financial support (2016/22561-2), V. R. Debastiani wishes to acknowledge the support from the Programa Santiago Grisolia of Generalitat Valenciana (Exp. GRISOLIA/2015/005). This work is also partly supported by the Spanish Ministerio de Economia y Competitividad and European FEDER funds (FIS2014-57026- REDT, FIS2014-51948-C2-1-P, FIS2014-51948-C2-2-P), and the Generalitat Valenciana in the program Prometeo II-2014/068. This work is partly supported by the National Natural Science Foundation of China (11475227, 11735003) and the Youth Innovation Promotion Association CAS (2016367)

A /sup 1/Pi--X /sup 1/. sigma. /sup +/ band system in CH/sup +/ and CD/sup +/: theoretical spectroscopic constants and lifetimes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Elander, N.; Oddershede, J.; Beebe, N.H.F.

1977-08-15

Polarization propagator calculation of spectroscopic constants and radiative lifetimes for the A /sup 1/Pi--X /sup 1/..sigma../sup +/ band system are presented. The spectroscopic constants agree well with experimental and other theoretical values. We have also performed an iterative Rydberg-Klein-Rees (RKR) calculation of B/sub e/, ..omega../sub e/, and ..omega../sub e/x/sub e/ for the experimental X /sup 1/..sigma../sup +/ state.The calculated radiative lifetime for the A /sup 1/Pi state (v'=0) is 660 ns and 598 ns, with theoretical and experimental potential energy curves, respectively. This difference (about 60 ns) indicates the inaccuracy in the present calculation. Experimentally the most recent estimate ofmore » the A /sup 1/Pi (v'=0) state is 630 +- 50 ns, and theoretically the Yoshimine et al. transition moment gives tau (A /sup 1/Pi, v'=0) =722 ns.The radiative lifetimes calculated for CD/sup +/ are between 1.3% and 3.9% larger than the corresponding CH/sup +/ lifetimes.« less

Light-meson masses in an unquenched quark model

NASA Astrophysics Data System (ADS)

Chen, Xiaoyun; Ping, Jialun; Roberts, Craig D.; Segovia, Jorge

2018-05-01

We perform a coupled-channels calculation of the masses of light mesons with the quantum numbers I JP =-, (I ,J )=0 , 1, by including q q ¯ and (q q ¯)2 components in a nonrelativistic chiral quark model. The coupling between two- and four-quark configurations is realized through a 3P0 quark-pair creation model. With the usual form of this operator, the mass shifts are large and negative, an outcome which raises serious issues of validity for the quenched quark model. Herein, therefore, we introduce some improvements of the 3P0 operator in order to reduce the size of the mass shifts. By introducing two simple factors, physically well motivated, the coupling between q q ¯ and (q q ¯)2 components is weakened, producing mass shifts that are around 10%-20% of hadron bare masses.

Viscosity of meson matter

NASA Astrophysics Data System (ADS)

Dobado, Antonio; Llanes-Estrada, Felipe J.

2004-06-01

We report a calculation of the shear viscosity in a relativistic multicomponent meson gas as a function of temperature and chemical potentials. We approximately solve the Uehling-Uhlenbeck transport equation of kinetic theory, appropriate for a boson gas, with relativistic kinematics. Since at low temperatures the gas can be taken as mostly composed of pions, with a fraction of kaons and etas, we explore the region where binary elastic collisions with at least one pion are the dominant scattering processes. Our input meson scattering phase shifts are fits to the experimental data obtained from chiral perturbation theory and the inverse amplitude method. Our results take the correct nonrelativistic limit (viscosity proportional to the square root of the temperature), show a viscosity of the order of the cube of the pion mass up to temperatures somewhat below that mass, and then a large increase due to kaons and etas. Our approximation may break down at even higher temperatures, where the viscosity follows a temperature power law with an exponent near 3.

Study of B to pi l nu and B to rho l nu Decays and Determination of |V_ub|

DOE Office of Scientific and Technical Information (OSTI.GOV)

del Amo Sanchez, P.; Lees, J.P.; Poireau, V.

2011-12-09

We present an analysis of exclusive charmless semileptonic B-meson decays based on 377 million B{bar B} pairs recorded with the BABAR detector at the {Upsilon} (4S) resonance. We select four event samples corresponding to the decay modes B{sup 0} {yields} {pi}{sup -}{ell}{sup +}{nu}, B{sup +} {yields} {pi}{sup 0}{ell}{sup +}{nu}, B{sup 0} {yields} {rho}{sup -}{ell}{sup +}{nu}, and B{sup +} {yields} {rho}{sup 0}{ell}{sup +}{nu}, and find the measured branching fractions to be consistent with isospin symmetry. Assuming isospin symmetry, we combine the two B {yields} {pi}{ell}{nu} samples, and similarly the two B {yields} {rho}{ell}{nu} samples, and measure the branching fractions {Beta}(B{sup 0}more » {yields} {pi}{sup -}{ell}{sup +}{nu}) = (1.41 {+-} 0.05 {+-} 0.07) x 10{sup -4} and {Beta}(B{sup 0} {yields} {rho}{sup 0}{ell}{sup +}{nu}) = (1.75 {+-} 0.15 {+-} 0.27) x 10{sup -4}, where the errors are statistical and systematic. We compare the measured distribution in q{sup 2}, the momentum transfer squared, with predictions for the form factors from QCD calculations and determine the CKM matrix element |V{sub ub}|. Based on the measured partial branching fraction for B {yields} {pi}{ell}{nu} in the range q{sup 2} < 12 GeV{sup 2} and the most recent LCSR calculations we obtain |V{sub ub}| = (3.78 {+-} 0.13{sub -0.40}{sup +0.55}) x 10{sup -3}, where the errors refer to the experimental and theoretical uncertainties. From a simultaneous fit to the data over the full q{sup 2} range and the FNAL/MILC lattice QCD results, we obtain |V{sub ub}| = (2.95 {+-} 0.31) x 10{sup -3} from B {yields} {pi}{ell}{nu}, where the error is the combined experimental and theoretical uncertainty.« less

Impact of scalar mesons on the rare B-decays

NASA Astrophysics Data System (ADS)

Issadykov, Aidos; Ivanov, Mikhail A.; Sakhiyev, Sayabek K.

2015-11-01

In the wake of exploring uncertainty in the full angular distribution of the B → Kπ + μ+μ- caused by the presence of the intermediate scalar K0∗ meson, we perform the straightforward calculation of the B(Bs) → S (S is a scalar meson) transition form factors in the full kinematical region within the covariant quark model. We restrict ourselves by the scalar mesons below 1 GeV: a0(980),f0(500),f0(980),K0∗(800). As an application of the obtained results we calculate the widths of the semileptonic and rare decays B(Bs) → Sℓν¯, B(Bs) → Sℓℓ¯ and B(Bs) → Sνν¯. We compare our results with those obtained in other approaches.

PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K.

PubMed

Malek, Mouhannad; Kielkowska, Anna; Chessa, Tamara; Anderson, Karen E; Barneda, David; Pir, Pınar; Nakanishi, Hiroki; Eguchi, Satoshi; Koizumi, Atsushi; Sasaki, Junko; Juvin, Véronique; Kiselev, Vladimir Y; Niewczas, Izabella; Gray, Alexander; Valayer, Alexandre; Spensberger, Dominik; Imbert, Marine; Felisbino, Sergio; Habuchi, Tomonori; Beinke, Soren; Cosulich, Sabina; Le Novère, Nicolas; Sasaki, Takehiko; Clark, Jonathan; Hawkins, Phillip T; Stephens, Len R

2017-11-02

The PI3K signaling pathway regulates cell growth and movement and is heavily mutated in cancer. Class I PI3Ks synthesize the lipid messenger PI(3,4,5)P 3 . PI(3,4,5)P 3 can be dephosphorylated by 3- or 5-phosphatases, the latter producing PI(3,4)P 2 . The PTEN tumor suppressor is thought to function primarily as a PI(3,4,5)P 3 3-phosphatase, limiting activation of this pathway. Here we show that PTEN also functions as a PI(3,4)P 2 3-phosphatase, both in vitro and in vivo. PTEN is a major PI(3,4)P 2 phosphatase in Mcf10a cytosol, and loss of PTEN and INPP4B, a known PI(3,4)P 2 4-phosphatase, leads to synergistic accumulation of PI(3,4)P 2 , which correlated with increased invadopodia in epidermal growth factor (EGF)-stimulated cells. PTEN deletion increased PI(3,4)P 2 levels in a mouse model of prostate cancer, and it inversely correlated with PI(3,4)P 2 levels across several EGF-stimulated prostate and breast cancer lines. These results point to a role for PI(3,4)P 2 in the phenotype caused by loss-of-function mutations or deletions in PTEN. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

Amplitude Analysis of the Decay $$D^+ \\to K_s \\pi^- \\pi^+ \\pi^+$$ in the {FOCUS} Experiment (in Portuguese)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Otalora Goicochea, Juan Martin

This thesis is devoted to the study of the decay D+ → KS π−π+π+ with data collected from the FOCUS experiment, at Fermilab. The fi state composed of 4 pseudo-scalars can be produced through a number of resonant sub-structures. The purpose of this analysis is to fi the contributing intermediate states by measuring their relative strenghts and phases. For that, the Amplitude Analysis formalism is used, with the so-called Isobar Model. The decay dynamics is described through a function which has the features of the contributing channels (functional forms of the resonances, angular distribution, etc) and which domain is amore » phase space determined by 5 invariants (due to the kinematical constraints of a 4-body spinless decay). The data sample is thus fi to this function. Our results show a dominant contribution of the axial-vector meson a1(1260) (52%), followed by the K1(1400) axial-vector (34%). Moreover, the model presents a contribution from the σ meson (about 8% as a1(σπ)KS and σKS π) and a significant contribution from the scalar κ−. The κ state has been reported in its neutral mode in other charm decays but not is its charged mode. We fi no significant contribution from the direct 4-body decay (non-resonant). This work adds to the effort in the understanding of the strong-interaction dynamics at low energies, which in recent years have been receiving an important contribution from charm meson physics.« less

Photoproduction of Scalar Mesons Using the CEBAF Large Acceptance Spectrometer (CLAS)

NASA Astrophysics Data System (ADS)

Chandavar, Shloka K.

The search for glueballs has been ongoing for several decades. The lightest glueball has been predicted by quenched lattice QCD to have mass in the range of 1.0--1.7 GeV and JPC = 0++ . The mixing of glueball states with neighbouring meson states complicates their identification and hence several experiments have been carried out over the years to study the glueball candidates. By analyzing the decay channels and production mechanisms of these candidates, their glueball content can theoretically be determined. In reality, a lot of confusion still exists about the status of these glueball candidates. The f0(1500) is one of several contenders for the lightest glueball, which has been extensively studied in several different kinds of experiments. However, there exists no photoproduction data on this particle. In the analysis presented in this dissertation, the presence of the f0(1500) in the KS 0KS0 channel is investigated in photoproduction using the CEBAF Large Acceptance Spectrometer (CLAS) at the Thomas Jefferson National Accelerator Facility, also called Jefferson Lab (JLab). This is done by studying the reaction, gammap → fJp → KS0 KS0p → 2(pi +pi-)p using data from the g12 experiment. A clear peak is seen at 1500 MeV in the background subtracted data. This is enhanced if the momentum transfer is restricted to be less than 1 GeV2. Comparing with simulations, it is seen that this peak is associated with t channel production mechanism. The f 2'(1525) has a mass of 1525 MeV and a width of 73 MeV, and hence there is a possibility of it contributing to the peak observed in our data. A moments analysis seems to suggest some presence of a D wave, however, the low acceptance at forward and backward angles prohibits a definitive conclusion.

Holographic estimate of the meson cloud contribution to nucleon axial form factor

NASA Astrophysics Data System (ADS)

Ramalho, G.

2018-04-01

We use light-front holography to estimate the valence quark and the meson cloud contributions to the nucleon axial form factor. The free couplings of the holographic model are determined by the empirical data and by the information extracted from lattice QCD. The holographic model provides a good description of the empirical data when we consider a meson cloud mixture of about 30% in the physical nucleon state. The estimate of the valence quark contribution to the nucleon axial form factor compares well with the lattice QCD data for small pion masses. Our estimate of the meson cloud contribution to the nucleon axial form factor has a slower falloff with the square momentum transfer compared to typical estimates from quark models with meson cloud dressing.

Light-cone distribution amplitudes of light JPC = 2- tensor mesons in QCD

NASA Astrophysics Data System (ADS)

Aliev, T. M.; Bilmis, S.; Yang, Kwei-Chou

2018-06-01

We present a study for two-quark light-cone distribution amplitudes for the 13D2 light tensor meson states with quantum number JPC =2-. Because of the G-parity, the chiral-even two-quark light-cone distribution amplitudes of this tensor meson are antisymmetric under the interchange of momentum fractions of the quark and antiquark in the SU(3) limit, while the chiral-odd ones are symmetric. The asymptotic leading-twist LCDAs with the strange quark mass correction are shown. We estimate the relevant parameters, the decay constants fT and fT⊥, and first Gegenbauer moment a1⊥ , by using the QCD sum rule method. These parameters play a central role in the investigation of B meson decaying into the 2- tensor mesons.

Meson thermalization by baryon injection in D4/D6 model

NASA Astrophysics Data System (ADS)

Rezaei, Z.

2016-12-01

We study meson thermalization in a strongly coupled plasma of quarks and gluons using AdS/CFT duality technique. Four dimensional large-Nc QCD is considered as a theory governing this quark-gluon plasma (QGP) and D4/D6-brane model is chosen to be its holographic dual theory. In order to investigate meson thermalization, we consider a time-dependent change of baryon number chemical potential. Thermalization in gauge theory side corresponds to horizon formation on the probe flavor brane in the gravity side. The gravitational dual theory is compactified on a circle that the inverse of its radius is proportional to energy scale of dual gauge theory. It is seen that increase of this energy scale results in thermalization time dilation. In addition we study the effect of magnetic field on meson thermalization. It will be seen that magnetic field also prolongs thermalization process by making mesons more stable.

QCD sum-rules analysis of vector (1-) heavy quarkonium meson-hybrid mixing

NASA Astrophysics Data System (ADS)

Palameta, A.; Ho, J.; Harnett, D.; Steele, T. G.

2018-02-01

We use QCD Laplace sum rules to study meson-hybrid mixing in vector (1-) heavy quarkonium. We compute the QCD cross-correlator between a heavy meson current and a heavy hybrid current within the operator product expansion. In addition to leading-order perturbation theory, we include four- and six-dimensional gluon condensate contributions as well as a six-dimensional quark condensate contribution. We construct several single and multiresonance models that take known hadron masses as inputs. We investigate which resonances couple to both currents and so exhibit meson-hybrid mixing. Compared to single resonance models that include only the ground state, we find that models that also include excited states lead to significantly improved agreement between QCD and experiment. In the charmonium sector, we find that meson-hybrid mixing is consistent with a two-resonance model consisting of the J /ψ and a 4.3 GeV resonance. In the bottomonium sector, we find evidence for meson-hybrid mixing in the ϒ (1 S ) , ϒ (2 S ), ϒ (3 S ), and ϒ (4 S ).

Electromagnetic Transition Form Factor of the η meson with WASA-at-COSY

NASA Astrophysics Data System (ADS)

Goswami, A.

2016-11-01

In this work we present a study of the Dalitz decay η → γe+e-. The aim of this work is to measure the transition form factor of the η meson. The transition form factor of the η meson describes the electromagnetic structure of the meson. The study of the Dalitz decay helps to calculate the transition form factor of the η meson. When a particle is point-like it's decay rate can be calculated within QED. However, the complex structure of the meson modifies its decay rate. The transition form factor is determined by comparing the lepton-antilepton invariant mass distribution with QED. For this study data on proton-proton reaction at a beam energy of 1.4 GeV has been collected with WASA-at-COSY detector at Forschungszentrum Juelich, Germany. In the higher invariant mass region recent theoretical calculations slightly deviate from the fit to the data. We expect better results in the higher invariant mass region than previous measurements. The preliminary results of the analysis will be presented.

The Chiral and Angular Momentum Content of the ρ-Meson

NASA Astrophysics Data System (ADS)

Glozman, L. Ya.; Lang, C. B.; Limmer, M.

2010-01-01

It is possible to define and calculate in a gauge-invariant manner the chiral as well as the partial wave content of the quark-antiquark Fock component of a meson in the infrared, where mass is generated. Using the variational method and a set of interpolators that span a complete chiral basis we extract in a lattice QCD Monte Carlo simulation with n f = 2 dynamical light quarks the orbital angular momentum and spin content of the ρ-meson. We obtain in the infrared a simple 3 S 1 component as a leading component of the ρ-meson with a small admixture of the 3 D 1 partial wave, in agreement with the SU(6) flavor-spin symmetry.

Light meson gas in the QCD vacuum and oscillating universe

NASA Astrophysics Data System (ADS)

Prokhorov, George; Pasechnik, Roman

2018-01-01

We have developed a phenomenological effective quantum-field theoretical model describing the "hadron gas" of the lightest pseudoscalar mesons, scalar σ-meson and σ-vacuum, i.e. the expectation value of the σ-field, at finite temperatures. The corresponding thermodynamic approach was formulated in terms of the generating functional derived from the effective Lagrangian providing the basic thermodynamic information about the "meson plasma + QCD condensate" system. This formalism enables us to study the QCD transition from the hadron phase with direct implications for cosmological evolution. Using the hypothesis about a positively-definite QCD vacuum contribution stochastically produced in early universe, we show that the universe could undergo a series of oscillations during the QCD epoch before resuming unbounded expansion.

Measuring the charged pion polarizability in the gamma gamma -> pi+pi- reaction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lawrence, David W.; Miskimen, Rory A.; Mushkarenkov, Alexander Nikolaevich

2013-08-01

Development has begun of a new experiment to measure the charged pion polarizabilitymore » $$\\alpha_{\\pi}-\\beta_{\\pi}$$. The charged pion polarizability ranks among the most important tests of low-energy QCD presently unresolved by experiment. Analogous to precision measurements of $$\\pi^{\\circ}\\rightarrow\\gamma\\gamma$$ that test the intrinsic odd-parity (anomalous) sector of QCD, the pion polarizability tests the intrinsic even-parity sector of QCD. The measurement will be performed using the $$\\gamma\\gamma\\rightarrow\\pi^{+{}}\\pi^{-{}}$$ cross section accessed via the Primakoff mechanism on nuclear targets using the GlueX detector in Hall D at Jefferson Lab. The linearly polarized photon source in Hall-D will be utilized to separate the Primakoff cross-section from coherent $$\\rho^{\\circ}$$ production.« less

PI3K/AKT signaling inhibits NOTCH1 lysosome-mediated degradation.

PubMed

Platonova, Natalia; Manzo, Teresa; Mirandola, Leonardo; Colombo, Michela; Calzavara, Elisabetta; Vigolo, Emilia; Cermisoni, Greta Chiara; De Simone, Daria; Garavelli, Silvia; Cecchinato, Valentina; Lazzari, Elisa; Neri, Antonino; Chiaramonte, Raffaella

2015-06-06

The pathways of NOTCH and PI3K/AKT are dysregulated in about 60% and 48% of T-cell acute lymphoblastic leukemia (T-ALL) patients, respectively. In this context, they interact and cooperate in controlling tumor cell biology. Here, we propose a novel mechanism by which the PI3K/AKT pathway regulates NOTCH1 in T-ALL, starting from the evidence that the inhibition of PI3K/AKT signaling induced by treatment with LY294002 or transient transfection with a dominant negative AKT mutant downregulates NOTCH1 protein levels and activity, without affecting NOTCH1 transcription. We showed that the withdrawal of PI3K/AKT signaling was associated to NOTCH1 phosphorylation in tyrosine residues and monoubiquitination of NOTCH1 detected by Ubiquitin capture assay. Co-immunoprecipitation assay and colocalization analysis further showed that the E3 ubiquitin ligase c-Cbl interacts and monoubiquitinates NOTCH1, activating its lysosomal degradation. These results suggest that the degradation of NOTCH1 could represent a mechanism of control by which NOTCH1 receptors are actively removed from the cell surface. This mechanism is finely regulated by the PI3K/AKT pathway in physiological conditions. In pathological conditions characterized by PI3K/AKT hyperactivation, such as T-ALL, the excessive AKT signaling could lead to NOTCH1 signaling dysregulation. Therefore, a therapeutic strategy directed to PI3K/AKT in T-ALL could contemporaneously inhibit the dysregulated NOTCH1 signaling. © 2015 Wiley Periodicals, Inc. © 2015 Wiley Periodicals, Inc.

Quasi-elastic electroproduction of charged ρ -mesons on nucleons

NASA Astrophysics Data System (ADS)

Sviridova, L. L.; Fedorov, D. K.; Neudatchin, V. G.; Obukhovsky, I. T.; Faessler, A.

2010-06-01

The electroproduction of charged ρ -mesons on the nucleon at intermediate energy is discussed for quasi-elastic kinematics. It is shown that at these kinematics both the longitudinal σ_{{L}}^{} and transverse σ_{{T}}^{} cross-sections are dominated by the ρ -meson t -pole contribution, and thus the corresponding dσ L( T)/d t data can give a valuable information on the ρ -meson component of the nucleon cloud. The differential cross-sections for the reaction p( e, e ' ρ+_{}) n at Q 2 = 2 , 3.5GeV^2 and at the invariant mass W = 3 and 4GeV are calculated on the basis of quasi-elastic knockout mechanism with form factors. Questions about the gauge invariance of the electroproduction amplitude are considered and it is noted an important difference between photo- and electroproduction amplitudes.

Quantitative characterization of brain β-amyloid in 718 normal subjects using a joint PiB/FDG PET image histogram

NASA Astrophysics Data System (ADS)

Camp, Jon J.; Hanson, Dennis P.; Lowe, Val J.; Kemp, Bradley J.; Senjem, Matthew L.; Murray, Melissa E.; Dickson, Dennis W.; Parisi, Joseph E.; Petersen, Ronald C.; Robb, Richard A.; Holmes, David R.

2016-03-01

We have previously described an automated system for the co-registration of PiB and FDG PET images with structural MRI and a neurological anatomy atlas to produce region-specific quantization of cortical activity and amyloid burden. We also reported a global joint PiB/FDG histogram-based measure (FDG-Associated PiB Uptake Ratio - FAPUR) that performed as well as regional PiB ratio in stratifying Alzheimer's disease (AD) and Lewy Body Dementia (LBD) patients from normal subjects in an autopsy-verified cohort of 31. In this paper we examine results of this analysis on a clinically-verified cohort of 718 normal volunteers. We found that the global FDG ratio correlated negatively with age (r2 = 0.044) and global PiB ratio correlated positively with age (r2=0.038). FAPUR also correlated negatively with age (r2-.025), and in addition, we introduce a new metric - the Pearson's correlation coefficient (r2) of the joint PiB/FDG histogram which correlates positively (r2=0.014) with age. We then used these measurements to construct age-weighted Z-scores for all measurements made on the original autopsy cohort. We found similar stratification using Z-scores compared to raw values; however, the joint PiB/FDG r2 Z-score showed the greatest stratification ability.

Negative Charged Pion Production on a Deuteron by Quasi-Real Photons

NASA Astrophysics Data System (ADS)

Gauzshtein, V. V.; Dusaev, R. R.; Loginov, A. Yu.; Nikolenko, D. M.; Sidorov, A. A.; Stibunov, V. N.

2013-12-01

Experimental differential cross sections of photoproduction of negative pions on a deuteron have been obtained as functions of the polar angle of emission of π- mesons. A comparison is made of the measured cross sections with the results of calculations in a model that takes account the interaction in the final state of the reaction.

Eta Meson Production in Proton-Proton and Nuclear Collisions

NASA Technical Reports Server (NTRS)

Norbury, John W.; Dick, Frank

2008-01-01

Total cross sections for eta meson production in proton - proton collisions are calculated. The eta meson is mainly produced via decay of the excited nucleon resonance at 1535 MeV. A scalar quantum field theory is used to calculate cross sections, which also include resonance decay. Comparison between theory and experiment is problematic near threshold when resonance decay is not included. When the decay is included, the comparison between theory and experiment is much better.

The role of different PI-RADS versions in prostate multiparametric magnetic resonance tomography assessment.

PubMed

Aliukonis, Paulius; Letauta, Tadas; Briedienė, Rūta; Naruševičiūtė, Ieva; Letautienė, Simona

2017-01-01

Background . Standardised Prostate Imaging Reporting and Data System (PI-RADS) guidelines for the assessment of prostate alterations were designed for the assessment of prostate pathology. Published by the ESUR in 2012, PI-RADS v1 was based on the total score of different MRI sequences with subsequent calculation. PI-RADS v2 was published by the American College of Radiology in 2015 and featured different assessment criteria for prostate peripheral and transitory zones. Aim . To assess the correlations of PI-RADS v1 and PI-RADS v2 with Gleason score values and to define their predictive values of the diagnosis of prostate cancer. Materials and methods . A retrospective analysis of 66 patients. Prostate specific antigen (PSA) value and the Gleason score (GS) were assessed. One the most malignant focal lesion was selected in the peripheral zone of each lobe of the prostate (91 in total). Statistical analysis was carried out applying SPSS software, v.23, p < 0.05. Results . Focal lesions assessed by PI-RADS v1 score: 10% - 1, 12% - 2, 41% - 3, 23% - 4, 14% - 5. Assessment applying PI-RADS v.2: 20% - 1, 7.5% - 2, 26%, 29.5%, and 17% were assessed by 3, 4, and 5 scores. Statistically relevant correlation was found only between GS and PI-RADS ( p = 0.033). The positive predictive value of both versions of PI-RADS - 75%, negative predictive value of PI-RADS v1 - 46%, PI-RADS v2 - 43%. Conclusions . PI-RADS v1 was more statistically relevant in assessing the grade of tumour. Prediction values were similar in both versions.

Heavy-light mesons in chiral AdS/QCD

NASA Astrophysics Data System (ADS)

Liu, Yizhuang; Zahed, Ismail

2017-06-01

We discuss a minimal holographic model for the description of heavy-light and light mesons with chiral symmetry, defined in a slab of AdS space. The model consists of a pair of chiral Yang-Mills and tachyon fields with specific boundary conditions that break spontaneously chiral symmetry in the infrared. The heavy-light spectrum and decay constants are evaluated explicitly. In the heavy mass limit the model exhibits both heavy-quark and chiral symmetry and allows for the explicit derivation of the one-pion axial couplings to the heavy-light mesons.

Nucleon resonances in exclusive reactions of photo- and electroproduction of mesons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Skorodumina, Iu. A.; Burkert, V. D.; Golovach, E. N.

2015-11-01

Methods for extracting nucleon resonance parameters from experimental data are reviewed. The formalism for the description of exclusive reactions of meson photo- and electroproduction off nucleons is discussed. Recent experimental data on exclusive meson production in the scattering of electrons and photons off protons are analyzed.

The Quest for Pi

NASA Technical Reports Server (NTRS)

Bailey, David H.; Borwein, Jonathan M.; Borwein, Peter B.; Plouffe, Simon

1996-01-01

This article gives a brief history of the analysis and computation of the mathematical constant Pi=3.14159 ..., including a number of the formulas that have been used to compute Pi through the ages. Recent developments in this area are then discussed in some detail, including the recent computation of Pi to over six billion decimal digits using high-order convergent algorithms, and a newly discovered scheme that permits arbitrary individual hexadecimal digits of Pi to be computed.

ω and η (η') Mesons from NN and nd Collisions at Intermediate Energies

NASA Astrophysics Data System (ADS)

Kaptari, L. P.; Kämpfer, B.

The production of pseudo scalar, η, η‧, and vector, ω, ρ, ϕ, mesons in NN collisions at threshold-near energies is analyzed within a covariant effective meson-nucleon theory. It is shown that a good description of cross sections and angular distributions, for vector meson production, can be accomplished by considering meson and nucleon currents only, while for pseudo scalar production an inclusion of nucleon resonances is needed. The di-electron production from subsequent Dalitz decay of the produced mesons, η‧ → γγ* → γe+e- and ω → πγ* → πe+e- is also considered and numerical results are presented for intermediate energies and kinematics of possible experiments with HADES, CLAS and KEK-PS. We argue that the transition form factor ω → γ*π as well as η‧ → γ*γ can be defined in a fairly model independent way and the feasibility of an experimental access to transition form factors is discussed.

Pseudoscalar Meson Electroproduction and Transversity

NASA Astrophysics Data System (ADS)

Goldstein, Gary R.; Liuti, Simonetta

2011-02-01

Exclusive meson leptoproduction from nucleons in the deeply virtual exchanged boson limit can be described by generalized parton distributions (GPDs). Including spin dependence in the description requires 8 independent quark-parton and gluon-parton functions. The chiral even subset of 4 quark-nucleon GPDs are related to nucleon form factors and to parton distribution functions. The chiral odd set of 4 quark-nucleon GPDs are related to transversity, the tensor charge, and other quantities related to transversity. Different meson or photon production processes access different combinations of GPDs. This is analyzed in terms of t-channel exchange quantum numbers, JPC and it is shown that pseudoscalar production can isolate chiral odd GPDs. There is a sensitive dependence in various cross sections and asymmetries on the tensor charge of the nucleon and other transversity parameters. In a second section, analyticity and completeness are shown to limit the partonic interpret ation of the GPDs in the ERBL region.

Exact Mesonic Eightfold Way From Dynamics and Confinement in Strongly Coupled Lattice QCD

NASA Astrophysics Data System (ADS)

Neto, A. Francisco; O'Carroll, M.; Faria da Veiga, P. A.

2009-01-01

We review our results on the exact determination of the mesonic eightfold way from first principles, directly from the quark-gluon dynamics. For this, we consider an imaginary-time functional integral formulation of 3 + 1 dimensional lattice QCD with Wilson action, three flavors, SU(3) f flavor symmetry and SU(3) c local gauge symmetry. We work in the strong coupling regime: a small hopping parameter κ>0 and a much smaller plaquette coupling β>0. By establishing a Feynman-Kac formula and a spectral representation to the two-meson correlation, we provide a rigorous connection between this correlation and the one-meson energy-momentum spectrum. The particle states can be labeled by the usual SU(3) f quantum numbers of total isospin I and its third-component I3, the quadratic Casimir C2 and, by a partial restoration of the continuous rotational symmetry on the lattice, as well as by the total spin J and its z-component Jz. We show that, up to near the two-meson energy threshold of ≈-4lnκ, the spectrum in the meson sector is given only by isolated dispersion curves of the eightfold way mesons. The mesons have all asymptotic mass of -2lnκ and, by deriving convergent expansions for the masses both in κ and β, we also show a κ mass splitting between the J=0,1 states. The splitting persists for β≠0. Our approach employs the decoupling of hyperplane method to uncover the basic excitations, complex analysis to determine the dispersion curves and a correlation subtraction method to show the curves are isolated. Using the latter and recalling our similar results for baryons, we also show confinement up to near the two-meson threshold.

Pion decay constant and the {rho}-meson mass at finite temperature in hidden local symmetry

DOE Office of Scientific and Technical Information (OSTI.GOV)

Harada, M.; Shibata, A.

1997-06-01

We study the temperature dependence of the pion decay constant and {rho}-meson mass in the hidden local symmetry model at one loop. Using the standard imaginary time formalism, we include the thermal effect of the {rho} meson as well as that of the pion. We show that the pion gives a dominant contribution to the pion decay constant and the {rho}-meson contribution slightly decreases the critical temperature. The {rho}-meson pole mass increases as T{sup 4}/m{sub {rho}}{sup 2} at low temperature, dominated by the pion-loop effect. At high temperature, although the pion-loop effect decreases the {rho}-meson mass, the {rho}-loop contribution overcomesmore » the pion-loop contribution and the {rho}-meson mass increases with temperature. We also show that the conventional parameter a is stable as the temperature increases. {copyright} {ital 1997} {ital The American Physical Society}« less

Light-meson masses in an unquenched quark model

DOE PAGES

Chen, Xiaoyun; Ping, Jialun; Roberts, Craig D.; ...

2018-05-17

We perform a coupled-channels calculation of the masses of light mesons with the quantum numbers IJ P=-, (I,J) = 0,1, by includingmore » $$q\\bar{q}$$ and ($$q\\bar{q}$$) 2 components in a nonrelativistic chiral quark model. The coupling between two- and four-quark configurations is realized through a 3P 0 quark-pair creation model. With the usual form of this operator, the mass shifts are large and negative, an outcome which raises serious issues of validity for the quenched quark model. Therefore, we introduce some improvements of the 3P 0 operator in order to reduce the size of the mass shifts. By introducing two simple factors, physically well motivated, the coupling between $$q\\bar{q}$$ and ($$q\\bar{q}$$) 2 components is weakened, producing mass shifts that are around 10%–20% of hadron bare masses.« less

Light-meson masses in an unquenched quark model

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen, Xiaoyun; Ping, Jialun; Roberts, Craig D.

We perform a coupled-channels calculation of the masses of light mesons with the quantum numbers IJ P=-, (I,J) = 0,1, by includingmore » $$q\\bar{q}$$ and ($$q\\bar{q}$$) 2 components in a nonrelativistic chiral quark model. The coupling between two- and four-quark configurations is realized through a 3P 0 quark-pair creation model. With the usual form of this operator, the mass shifts are large and negative, an outcome which raises serious issues of validity for the quenched quark model. Therefore, we introduce some improvements of the 3P 0 operator in order to reduce the size of the mass shifts. By introducing two simple factors, physically well motivated, the coupling between $$q\\bar{q}$$ and ($$q\\bar{q}$$) 2 components is weakened, producing mass shifts that are around 10%–20% of hadron bare masses.« less

Pharmacological inhibition of PI3K reduces adiposity and metabolic syndrome in obese mice and rhesus monkeys.

PubMed

Ortega-Molina, Ana; Lopez-Guadamillas, Elena; Mattison, Julie A; Mitchell, Sarah J; Muñoz-Martin, Maribel; Iglesias, Gema; Gutierrez, Vincent M; Vaughan, Kelli L; Szarowicz, Mark D; González-García, Ismael; López, Miguel; Cebrián, David; Martinez, Sonia; Pastor, Joaquin; de Cabo, Rafael; Serrano, Manuel

2015-04-07

Genetic inhibition of PI3K signaling increases energy expenditure, protects from obesity and metabolic syndrome, and extends longevity. Here, we show that two pharmacological inhibitors of PI3K, CNIO-PI3Ki and GDC-0941, decrease the adiposity of obese mice without affecting their lean mass. Long-term treatment of obese mice with low doses of CNIO-PI3Ki reduces body weight until reaching a balance that is stable for months as long as the treatment continues. CNIO-PI3Ki treatment also ameliorates liver steatosis and decreases glucose serum levels. The above observations have been recapitulated in independent laboratories and using different oral formulations of CNIO-PI3Ki. Finally, daily oral treatment of obese rhesus monkeys for 3 months with low doses of CNIO-PI3Ki decreased their adiposity and lowered their serum glucose levels, in the absence of detectable toxicities. Therefore, pharmacological inhibition of PI3K is an effective and safe anti-obesity intervention that could reverse the negative effects of metabolic syndrome in humans. Copyright © 2015 Elsevier Inc. All rights reserved.

Photoproduction of vector mesons in proton-proton ultraperipheral collisions at the CERN Large Hadron Collider

NASA Astrophysics Data System (ADS)

Xie, Ya-Ping; Chen, Xurong

2018-05-01

Photoproduction of vector mesons is computed with dipole model in proton-proton ultraperipheral collisions (UPCs) at the CERN Large Hadron Collider (LHC). The dipole model framework is employed in the calculations of vector mesons production in diffractive processes. Parameters of the bCGC model are refitted with the latest inclusive deep inelastic scattering experimental data. Employing the bCGC model and boosted Gaussian light-cone wave function for vector mesons, we obtain the prediction of rapidity distributions of J/ψ and ψ(2s) mesons in proton-proton ultraperipheral collisions at the LHC. The predictions give a good description of the experimental data of LHCb. Predictions of ϕ and ω mesons are also evaluated in this paper.

Dipion invariant mass distribution of the anomalous {Upsilon}(1S){pi}{sup +}{pi}{sup -} and {Upsilon}(2S){pi}{sup +}{pi}{sup -} production near the peak of {Upsilon}(10860)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Chen Dianyong; He Jun; Nuclear Theory Group, Institute of Modern Physics of CAS, Lanzhou 730000

2011-10-01

Considering the defects of the previous work for estimating the anomalous production rates of e{sup +}e{sup -}{yields}{Upsilon}(1S){pi}{sup +}{pi}{sup -}, {Upsilon}(2S){pi}{sup +}{pi}{sup -} near the peak of the {Upsilon}(5S) resonance at {radical}(s)=10.87 GeV [K. F. Chen et al. (Belle Collaboration), Phys. Rev. Lett. 100, 112001 (2008)], we suggest a new scenario where the contributions from the direct dipion transition and the final-state interactions interfere to result in not only the anomalously large production rates, but also line shapes of the differential widths consistent with experimental measurement when assuming the reactions are due to the dipion emission of {Upsilon}(5S). At the end,more » we raise a new puzzle that the predicted differential width d{Gamma}({Upsilon}(5S){yields}{Upsilon}(2S){pi}{sup +}{pi}{sup -})/dcos{theta} has a discrepant trend from the data while other predictions are well in accord with the data. It should be further clarified by more accurate measurements carried by future experiments.« less

MESTRN: A Deterministic Meson-Muon Transport Code for Space Radiation

NASA Technical Reports Server (NTRS)

Blattnig, Steve R.; Norbury, John W.; Norman, Ryan B.; Wilson, John W.; Singleterry, Robert C., Jr.; Tripathi, Ram K.

2004-01-01

A safe and efficient exploration of space requires an understanding of space radiations, so that human life and sensitive equipment can be protected. On the way to these sensitive sites, the radiation fields are modified in both quality and quantity. Many of these modifications are thought to be due to the production of pions and muons in the interactions between the radiation and intervening matter. A method used to predict the effects of the presence of these particles on the transport of radiation through materials is developed. This method was then used to develop software, which was used to calculate the fluxes of pions and muons after the transport of a cosmic ray spectrum through aluminum and water. Software descriptions are given in the appendices.

Role of the ρ meson in the description of pion electroproduction experiments

NASA Astrophysics Data System (ADS)

Faessler, Amand; Gutsche, Thomas; Lyubovitskij, Valery E.; Obukhovsky, Igor T.

2007-08-01

We study the p(e,e'π+)n reaction in the framework of an effective Lagrangian approach including nucleon, π and ρ meson degrees of freedom and show the importance of the ρ-meson t-pole contribution to σT, the transverse part of cross section. We test two different field representations of the ρ meson, vector and tensor, and find that the tensor representation of the ρ meson is more reliable in the description of the existing data. In particular, we show that the ρ-meson t-pole contribution, including the interference with an effective nonlocal contact term, sufficiently improves the description of the recent JLab data at invariant mass W≲2.2 GeV and Q2≲2.5 GeV2/c2. A “soft” variant of the strong πNN and ρNN form factors is also found to be compatible with these data. On the basis of the successful description of both the σL and σT parts of the cross section we discuss the importance of taking into account the σT data when extracting the charge pion form factor Fπ from σL.

Exotic meson decays in the environment with chiral imbalance

NASA Astrophysics Data System (ADS)

Andrianov, A. A.; Andrianov, V. A.; Espriu, D.; Iakubovich, A. V.; Putilova, A. E.

2017-10-01

An emergence of Local Parity Breaking (LPB) in central heavy-ion collisions (HIC) at high energies is discussed. LPB in the fireball can be produced by a difference between the number densities of right- and left-handed chiral fermions (Chiral Imbalance) which is implemented by a chiral (axial) chemical potential. The effective meson lagrangian induced by QCD is extended to the medium with Chiral Imbalance and the properties of light scalar and pseudoscalar mesons (π, α0) are analyzed. It is shown that exotic decays of scalar mesons arise as a result of mixing of π and α0 vacuum states in the presence of chiral imbalance. The pion electromagnetic formfactor obtains an unusual parity-odd supplement which generates a photon polarization asymmetry in pion polarizability. We hope that the above pointed indications of LPB can be identified in experiments on LHC, RHIC, CBM FAIR and NICA accelerators.

Validation of PI-RADS version 2 for the detection of prostate cancer.

PubMed

Hofbauer, Sebastian L; Kittner, Beatrice; Maxeiner, Andreas; Heckmann, Robin; Reimann, Maximillian; Wiemer, Laura; Asbach, Patrick; Haas, Matthias; Penzkofer, Tobias; Stephan, Carsten; Friedersdorff, Frank; Fuller, Florian; Miller, Kurt; Cash, Hannes

2018-05-04

The second version of the Prostate Imaging Reporting and Data System (PI-RADSv2) was introduced in 2015 to standardize the interpretation and reporting of multiparametric prostate magnetic resonance imaging (mpMRI). Recently, low cancer detection rates (CDR) for PI-RADSv2 category 4 lesions were reported. Therefore the aim of the study was to evaluate the CDR of PI-RADSv2 in a large prospective cohort. The study included 704 consecutive men with primary or prior negative biopsies who underwent MRI/ultrasound fusion-guided targeted biopsy (TB) and 10-core systematic prostate biopsy (SB) between September 2015 and May 2017. All lesions were rated according to PI-RADSv2 and lesions with PI-RADSv2 category ≥ 3 were biopsied. An ISUP (International Society of Urological Pathology) score of 2 or greater (i.e. Gleason 3+4 or greater) was defined as clinically significant prostate cancer (csPCa). The overall CDR for PI-RADSv2 categories 3, 4, and 5 was 39%, 72%, and 91% for all PCa, and 23%, 49%, and 77% for all csPCa, respectively. Fifty-nine (16%) clinically significant tumors would have been missed if only TB was performed. The PI-RADSv2 score was significantly associated with the presence of PCa (p<0.001), the presence of csPCa (p<0.001), and the ISUP grading (p<0.001). PI-RADSv2 is significantly associated with the presence of csPCa. The CDR for PI-RADSv2 category 4 lesions was considerably higher than previously reported. When performing TB, the combination with a SB still warrants the highest detection of csPCa. Copyright © 2018 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

Acoustic manipulation of active spherical carriers: Generation of negative radiation force

DOE Office of Scientific and Technical Information (OSTI.GOV)

Rajabi, Majid, E-mail: majid_rajabi@iust.ac.ir; Mojahed, Alireza

2016-09-15

This paper examines theoretically a novel mechanism of generating negative (pulling) radiation force for acoustic manipulation of spherical carriers equipped with piezoelectric actuators in its inner surface. In this mechanism, the spherical particle is handled by common plane progressive monochromatic acoustic waves instead of zero-/higher- order Bessel beams or standing waves field. The handling strategy is based on applying a spatially uniform harmonic electrical voltage at the piezoelectric actuator with the same frequency of handling acoustic waves, in order to change the radiation force effect from repulsive (away from source) to attractive (toward source). This study may be considered asmore » a start point for development of contact-free precise handling and entrapment technology of active carriers which are essential in many engineering and medicine applications.« less

Potential description of charmonium and charmed-strange mesons from lattice QCD

NASA Astrophysics Data System (ADS)

Kawanai, Taichi; Sasaki, Shoichi

2015-11-01

We present spin-independent and spin-spin interquark potentials for the charmonium and charmed-strange mesons, which are calculated in 2 +1 flavor lattice QCD simulations using the PACS-CS gauge configurations generated at the lightest pion mass (Mπ≈156 (7 ) MeV ) with a lattice cutoff of a-1≈2.2 GeV and a spatial volume of (3 fm )3 . For the charm quark, we use a relativistic heavy quark (RHQ) action with fine tuned RHQ parameters, which closely reproduce both the experimental spin-averaged mass and hyperfine splitting of the 1 S charmonium. The interquark potential and the quark kinetic mass, both of which are key ingredients within the potential description of heavy-heavy and heavy-light mesons, are determined from the equal-time Bethe-Salpeter (BS) amplitude. The charmonium potentials are obtained from the BS wave function of 1 S charmonia (ηc and J /ψ mesons), while the charmed-strange potential are calculated from the Ds and Ds* heavy-light mesons. We then use resulting potentials and quark masses as purely theoretical inputs so as to solve the nonrelativistic Schrödinger equation for calculating accessible energy levels of charmonium and charmed-strange mesons without unknown parameters. The resultant spectra below the D D ¯ and D K thresholds excellently agree with well-established experimental data.

Phenomenological study of the isovector tensor meson family

NASA Astrophysics Data System (ADS)

Pang, Cheng-Qun; He, Li-Ping; Liu, Xiang; Matsuki, Takayuki

2014-07-01

In this work, we study all the observed a2 states and group them into the a2 meson family, where their total and two-body Okubo-Zweig-Iizuka allowed strong decay partial widths are calculated via the quark pair creation model. Taking into account the present experimental data, we further give the corresponding phenomenological analysis, which is valuable to test whether each a2 state can be assigned into the a2 meson family. What is more important is that the prediction of their decay behaviors will be helpful for future experimental study of the a2 states.

Charmed-meson decay constants in three-flavor lattice QCD.

PubMed

Aubin, C; Bernard, C; Detar, C; Di Pierro, M; Freeland, E D; Gottlieb, Steven; Heller, U M; Hetrick, J E; El-Khadra, A X; Kronfeld, A S; Levkova, L; Mackenzie, P B; Menscher, D; Maresca, F; Nobes, M; Okamoto, M; Renner, D; Simone, J; Sugar, R; Toussaint, D; Trottier, H D

2005-09-16

We present the first lattice QCD calculation with realistic sea quark content of the D+-meson decay constant f(D+). We use the MILC Collaboration's publicly available ensembles of lattice gauge fields, which have a quark sea with two flavors (up and down) much lighter than a third (strange). We obtain f(D+)=201+/-3+/-17 MeV, where the errors are statistical and a combination of systematic errors. We also obtain f(Ds)=249+/-3+/-16 MeV for the Ds meson.

Electromagnetic Radiation in the Atmosphere Generated by Excess Negative Charge in a Nuclear-Electromagnetic Cascade

NASA Astrophysics Data System (ADS)

Malyshevsky, V. S.; Fomin, G. V.

2017-01-01

On the basis of the analytical model "PARMA" (PHITS-based Analytical Radiation Model in the Atmosphere), developed to model particle fluxes of secondary cosmic radiation in the Earth's atmosphere, we have calculated the characteristics of radio waves emitted by excess negative charge in an electromagnetic cascade. The results may be of use in an analysis of experimental data on radio emission of electron-photon showers in the atmosphere.

Probing for new physics in B meson decays with dilepton events

NASA Astrophysics Data System (ADS)

Park, Woochun

We have searched a sample of 9.6 M BB¯ events collected with the CLEO II detector in e+e - annihilations at the Upsilon(4S) resonance for B meson decays as follows: (1) The flavor-changing neutral current decays, B → K ℓ +ℓ- and B → K*(892)ℓ+ℓ- with mℓℓ > 0.5 GeV. (2) The lepton-flavor-violating decays, B → h e+/-mu ∓, B+ → h -e+e +, B+ → h -e+mu+, and B+ → h-mu +mu+, where h is pi, K, rho and K*(892), a total of sixteen modes. (3) The lepton-flavor-violating leptonic decays including tau lepton, B0 → mu+/-tau ∓ and B0 → e +/-tau∓. We find no evidence for these decays, and place 90% confidence level upper limits on their branching fractions: (1) B (B → K ℓ+ℓ -) < 1.7 x 10-6 and B (B → K*ℓ+ℓ -) mℓℓ > 0.5GeV < 3.3 x 10-6. (2) B (B → h ℓ ℓ) upper limits range from 1.0 to 8.0 x 10-6. (3) B (B0 → mu+/-tau ∓) < 3.8 x 10-5 and B (B0 → e +/-tau∓) < 1.3 x 10-4 .

Measurement of meson resonance production in $$\\pi ^- + C$$ interactions at SPS energies: The NA61/SHINE Collaboration

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aduszkiewicz, A.; Ali, Y.; Andronov, E. V.

Here, we present measurements ofmore » $$\\rho^0$$, $$\\omega$$ and K$$^{*0}$$ spectra in $$\\pi^{-} + $$C production interactions at 158 GeV/c and $$\\rho^0$$ spectra at 350 GeV/c using the NA61/SHINE spectrometer at the CERN SPS. Spectra are presented as a function of the Feynman's variable $$x_\\text{F}$$ in the range $$0 < x_\\text{F} < 1$$ and $$0 < x_\\text{F} < 0.5$$ for 158 GeV/c and 350 GeV/c respectively. Furthermore, we show comparisons with previous measurements and predictions of several hadronic interaction models. Our measurements are essential for a better understanding of hadronic shower development and for improving the modeling of cosmic ray air showers.« less

Measurement of meson resonance production in $$\\pi ^- + C$$ interactions at SPS energies: The NA61/SHINE Collaboration

DOE PAGES

Aduszkiewicz, A.; Ali, Y.; Andronov, E. V.; ...

2017-09-20

Here, we present measurements ofmore » $$\\rho^0$$, $$\\omega$$ and K$$^{*0}$$ spectra in $$\\pi^{-} + $$C production interactions at 158 GeV/c and $$\\rho^0$$ spectra at 350 GeV/c using the NA61/SHINE spectrometer at the CERN SPS. Spectra are presented as a function of the Feynman's variable $$x_\\text{F}$$ in the range $$0 < x_\\text{F} < 1$$ and $$0 < x_\\text{F} < 0.5$$ for 158 GeV/c and 350 GeV/c respectively. Furthermore, we show comparisons with previous measurements and predictions of several hadronic interaction models. Our measurements are essential for a better understanding of hadronic shower development and for improving the modeling of cosmic ray air showers.« less

Λ N → NN EFT potentials and hypertriton non-mesonic weak decay

NASA Astrophysics Data System (ADS)

Pérez-Obiol, Axel; Entem, David R.; Nogga, Andreas

2018-05-01

The potential for the Λ N → NN weak transition, the main responsible for the non-mesonic weak decay of hypernuclei, has been developed within the framework of effective field theory (EFT) up to next-to-leading order (NLO). The leading order (LO) and NLO contributions have been calculated in both momentum and coordinate space, and have been organised into the different operators which mediate the N → NN transition. We compare the ranges of the one-meson and two-pion exchanges for each operator. The non-mesonic weak decay of the hypertriton has been computed within the plane-wave approximation using the LO weak potential and modern strong EFT NN potentials. Formally, two methods to calculate the final state interactions among the decay products are presented. We briefly comment on the calculation of the {}{{Λ }}{}3H{\\to }3 He+{π }- mesonic weak decay.

Heavy-Meson Spectrum Tests of the Oktay--Kronfeld Action

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bailey, Jon A.; Jang, Yong-Chull; Lee, Weonjong

2014-11-07

We present heavy-meson spectrum results obtained using the Oktay--Kronfeld (OK) action on MILC asqtad lattices. The OK action was designed to improve the heavy-quark action of the Fermilab formulation, such that heavy-quark discretization errors are reduced. The OK action includes dimension-6 and -7 operators necessary for tree-level matching to QCD through ordermore » $$\\mathrm{O}(\\Lambda^3/m_Q^3)$$ for heavy-light mesons and $$\\mathrm{O}(v^6)$$ for quarkonium, or, equivalently, through $$\\mathrm{O}(a^2)$$ with some $$\\mathrm{O}(a^3)$$ terms with Symanzik power counting. To assess the improvement, we extend previous numerical tests with heavy-meson masses by analyzing data generated on a finer ($$a \\approx 0.12\\;$$fm) lattice with the correct tadpole factors for the $$c_5$$ term in the action. We update the analyses of the inconsistency parameter and the hyperfine splittings for the rest and kinetic masses.« less

Onset of η-meson binding in the He isotopes

NASA Astrophysics Data System (ADS)

Barnea, N.; Friedman, E.; Gal, A.

2017-12-01

The onset of binding η (548) mesons in nuclei is studied in the He isotopes by doing precise ηNNN and ηNNNN few-body stochastic variational method calculations for two semi-realistic NN potentials and two energy dependent ηN potentials derived from coupled-channel models of the N* (1535) nucleon resonance. The energy dependence of the ηN subthreshold input is treated self consistently. It is found that a minimal value of the real part of the ηN scattering length aηN close to 1 fm is required to bind η mesons in 3He, yielding then a few MeV η binding in 4He. The onset of η-meson binding in 4He requires that Re aηN exceeds 0.7 fm approximately. These results compare well with results of recent ηNNN and ηNNNN pionless effective field theory calculations. Related optical-model calculations are also discussed.

A meson-baryon molecular interpretation for some Ωc excited states

NASA Astrophysics Data System (ADS)

Montaña, Glòria; Feijoo, Albert; Ramos, Àngels

2018-04-01

We explore the possibility that some of the five narrow Ωc resonances recently observed at LHCb could correspond to pentaquark states, structured as meson-baryon bound states or molecules. The interaction of the low-lying pseudoscalar mesons with the ground-state baryons in the charm +1 , strangeness -2 and isospin 0 sector is built from t-channel vector meson exchange, using effective Lagrangians. The resulting s-wave coupled-channel unitarized amplitudes show the presence of two structures with similar masses and widths to those of the observed Ωc(3050)0 and Ωc(3090)0. The identification of these resonances with the meson-baryon bound states found in this work would also imply assigning the values 1/2- for their spin-parity. An experimental determination of the spin-parity of the Ωc(3090)0 would contribute to a better understanding of its structure, as the quark-based models predict its spin-parity to be either 3/2- or 5/2-. Predictions for the analogue bottom Ωb- resonances are also given.

In-medium properties of pseudoscalar D_s and B_s mesons

NASA Astrophysics Data System (ADS)

Chhabra, Rahul; Kumar, Arvind

2017-11-01

We calculate the shift in the masses and decay constants of D_s(1968) and B_s(5370) mesons in hot and dense asymmetric strange hadronic matter using QCD sum rules and chiral SU(3) model. In-medium strange quark condensates < \\bar{s}s> _{ρ _B}, and gluon condensates < α s/π {G^a}_{μ ν } {G^a}^{μ ν } > _{ρ _B}, to be used in the QCD sum rules for pseudoscalar D_s and B_s mesons, are calculated using a chiral SU(3) model. As an application of our present work, we calculate the in-medium decay widths of the excited (c\\bar{s}) states D_s^*(2715) and D_s^*(2860) decaying to (D_s(1968),η ) mesons. The medium effects in their decay widths are incorporated through the mass modification of the D_s(1968) and η mesons. The results of the present investigation may be helpful in understanding the possible outcomes of the future experiments like CBM and PANDA under the FAIR facility.

Characteristics of lead-glass γ-spectrometer radiators irradiated by high energy particles

NASA Astrophysics Data System (ADS)

Inyakin, A. V.; Kakauridze, D. B.; Lednev, A. A.; Prokoshkin, Yu. D.; Singovsky, A. V.

1983-09-01

Changes in the transparency of lead-glass radiators (F8, TF1 and F101 types), irradiated with 70 GeV protons and 30 GeV π mesons, have been studied. A universal dependence has been derived describing the behaviour of the radiator transparency as well as the characteristics of GAMS-type spectrometers after irradiation.

Pi Division and Addition

ERIC Educational Resources Information Center

Scott, Paul

2008-01-01

The number Pi (approximately 3.14159) is defined to be the ratio C/d of the circumference (C) to the diameter (d) of any given circle. In particular, Pi measures the circumference of a circle of diameter d = 1. Historically, the Greek mathematician Archimedes found good approximations for Pi by inscribing and circumscribing many-sided polygons…

A search for ϕ meson nucleus bound state using antiproton annihilation on nucleus

NASA Astrophysics Data System (ADS)

Ohnishi, H.; Bühler, P.; Cargnelli, M.; Curceanu, C.; Guaraldo, C.; Hartmann, O.; Hicks, K.; Iwasaki, M.; Ishiwatari, T.; Kienle, P.; Marton, J.; Muto, R.; Naruki, M.; Niiyama, M.; Noumi, H.; Okada, S.; Vidal, A. Romero; Sakaguchi, A.; Sakuma, F.; Sawada, S.; Sirghi, D.; Sirghi, F.; Suzuki, K.; Tsukada, K.; Doce, O. Vazquez; Widmann, E.; Yokkaichi, S.; Zmeskal, J.

2012-12-01

The mass shift of the vector mesons in nuclei is known to be a powerful tool for investigating the mechanism of generating hadron mass from the QCD vacuum. The mechanism is known to be the spontaneous breaking of chiral symmetry. In 2007, KEK-PS E325 experiment reported about 3.4 % mass reduction of the ϕ meson in medium-heavy nuclei (Cu). This result is possibly one of the indications of the partial restoration of chiral symmetry in nuclei, however, unfortunately it is hard to make strong conclusions from the data. One of the ways to conclude the strength of the ϕ meson mass shift in nuclei will be by trying to produce only slowly moving ϕ mesons where the maximum nuclear matter effect can be probed. The observed mass reduction of the ϕ meson in the nucleus can be translated as the existence of an attractive force between ϕ meson and nucleus. Thus, one of the extreme conditions that can be achieved in the laboratory is indeed the formation of a ϕ-nucleus bound state, where the ϕ meson is "trapped" in the nucleus. The purpose of the experiment is to search for a ϕ-nucleus bound state and measure the binding energy of the system. We will demonstrate that a completely background-free missing-mass spectrum can be obtained efficiently by (bar{p}, φ) spectroscopy together with K + Λ tagging, using the primary reaction channel bar{p} p rightarrow φ φ. This paper gives an overview of the physics motivation and the detector concept, and explains the direction of the initial research and development effort.

A search for ϕ meson nucleus bound state using antiproton annihilation on nucleus

NASA Astrophysics Data System (ADS)

Ohnishi, H.; Bühler, P.; Cargnelli, M.; Curceanu, C.; Guaraldo, C.; Hartmann, O.; Hicks, K.; Iwasaki, M.; Ishiwatari, T.; Kienle, P.; Marton, J.; Muto, R.; Naruki, M.; Niiyama, M.; Noumi, H.; Okada, S.; Vidal, A. Romero; Sakaguchi, A.; Sakuma, F.; Sawada, S.; Sirghi, D.; Sirghi, F.; Suzuki, K.; Tsukada, K.; Doce, O. Vazquez; Widmann, E.; Yokkaichi, S.; Zmeskal, J.

The mass shift of the vector mesons in nuclei is known to be a powerful tool for investigating the mechanism of generating hadron mass from the QCD vacuum. The mechanism is known to be the spontaneous breaking of chiral symmetry. In 2007, KEK-PS E325 experiment reported about 3.4 % mass reduction of the ϕ meson in medium-heavy nuclei (Cu). This result is possibly one of the indications of the partial restoration of chiral symmetry in nuclei, however, unfortunately it is hard to make strong conclusions from the data. One of the ways to conclude the strength of the ϕ meson mass shift in nuclei will be by trying to produce only slowly moving ϕ mesons where the maximum nuclear matter effect can be probed. The observed mass reduction of the ϕ meson in the nucleus can be translated as the existence of an attractive force between ϕ meson and nucleus. Thus, one of the extreme conditions that can be achieved in the laboratory is indeed the formation of a ϕ-nucleus bound state, where the ϕ meson is "trapped" in the nucleus. The purpose of the experiment is to search for a ϕ-nucleus bound state and measure the binding energy of the system. We will demonstrate that a completely background-free missing-mass spectrum can be obtained efficiently by (bar{p}, φ) spectroscopy together with K + Λ tagging, using the primary reaction channel bar{p} p rightarrow φ φ. This paper gives an overview of the physics motivation and the detector concept, and explains the direction of the initial research and development effort.

Nitrogen-Doping Enables Covalent-Like pi-pi Bonding between Graphenes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tian, Yong-Hui; Huang, Jingsong; Sumpter, Bobby G

The neighboring layers in bi-layer (and few-layer) graphenes of both AA and AB stacking motifs are known to be separated at a distance corresponding to van der Waals (vdW) interactions. In this Letter, we present for the first time a new aspect of graphene chemistry in terms of a special chemical bonding between the giant graphene molecules . Through rigorous theoretical calculations, we demonstrate that the N-doped graphenes (NGPs) with various doping levels can form an unusual two-dimensional (2D) pi pi bonding in bi-layer NGPs bringing the neighboring NGPs to significantly reduced interlayer separations. The interlayer binding energies can bemore » enhanced by up to 50% compared to the pristine graphene bi-layers that are characterized by only vdW interactions. Such an unusual chemical bonding arises from the pi pi overlap across the vdW gap while the individual layers maintain their in-plane pi-conjugation and are accordingly planar. The existence of the resulting interlayer covalent-like bonding is corroborated by electronic structure calculations and crystal orbital overlap population (COOP) analyses. In NGP-based graphite with the optimal doping level, the NGP layers are uniformly stacked and the 3D bulk exhibits metallic characteristics both in the in-plane and along the stacking directions.« less

In-medium pseudoscalar D/B mesons and charmonium decay width

NASA Astrophysics Data System (ADS)

Chhabra, Rahul; Kumar, Arvind

2017-05-01

Using QCD sum rules and the chiral SU(3) model, we investigate the effect of temperature, density, strangeness fraction and isospin asymmetric parameter on the shift in masses and decay constants of the pseudoscalar D and B meson in the hadronic medium, which consist of nucleons and hyperons. The in-medium properties of D and B mesons within the QCD sum rule approach depend upon the quark and gluon condensates. In the chiral SU(3) model, quark and gluon condensates are introduced through the explicit symmetry breaking term and the trace anomaly property of the QCD, respectively and are written in terms of the scalar fields σ, ζ, δ and χ. Hence, through medium modification of σ, ζ, δ and χ fields, we obtain the medium-modified masses and decay constants of D and B mesons. As an application, using {}3P0 model, we calculate the in-medium decay width of the higher charmonium states ψ(3686), ψ(3770) and χ(3556) to the D\\bar{D} pairs, considering the in-medium mass of D mesons. These results may be important to understand the possible outcomes of the high-energy physics experiments, e.g., CBM and PANDA at GSI, Germany.

p53 is a major component of the transcriptional and apoptotic program regulated by PI 3-kinase/Akt/GSK3 signaling.

PubMed

Nayak, G; Cooper, G M

2012-10-11

The phosphatidylinositol (PI) 3-kinase/Akt signaling pathway has a prominent role in cell survival and proliferation, in part, by regulating gene expression at the transcriptional level. Previous work using global expression profiling identified FOXOs and the E-box-binding transcription factors MITF and USF1 as key targets of PI 3-kinase signaling that lead to the induction of proapoptotic and cell cycle arrest genes in response to inhibition of PI 3-kinase. In this study, we investigated the role of p53 downstream of PI 3-kinase signaling by analyzing the effects of inhibition of PI 3-kinase in Rat-1 cells, which have wild-type p53, compared with Rat-1 cells expressing a dominant-negative p53 mutant. Expression of dominant-negative p53 conferred partial resistance to apoptosis induced by inhibition of PI 3-kinase. Global gene expression profiling combined with computational and experimental analysis of transcription factor binding sites demonstrated that p53, along with FOXO, MITF and USF1, contributed to gene induction in response to PI 3-kinase inhibition. Activation of p53 was mediated by phosphorylation of the histone acetyltransferase Tip60 by glycogen synthase kinase (GSK) 3, leading to activation of p53 by acetylation. Many of the genes targeted by p53 were also targeted by FOXO and E-box-binding transcription factors, indicating that p53 functions coordinately with these factors to regulate gene expression downstream of PI 3-kinase/Akt/GSK3 signaling.

Mass spectrum and decay constants of radially excited vector mesons

NASA Astrophysics Data System (ADS)

Mojica, Fredy F.; Vera, Carlos E.; Rojas, Eduardo; El-Bennich, Bruno

2017-07-01

We calculate the masses and weak decay constants of flavorless and flavored ground and radially excited JP=1- mesons within a Poincaré covariant continuum framework based on the Bethe-Salpeter equation. We use in both the quark's gap equation and the meson bound-state equation an infrared massive and finite interaction in the leading symmetry-preserving truncation. While our numerical results are in rather good agreement with experimental values where they are available, no single parametrization of the QCD inspired interaction reproduces simultaneously the ground and excited mass spectrum, which confirms earlier work on pseudoscalar mesons. This feature being a consequence of the lowest truncation, we pin down the range and strength of the interaction in both cases to identify common qualitative features that may help to tune future interaction models beyond the rainbow-ladder approximation.

Four-body decays of B meson with lepton number violation

NASA Astrophysics Data System (ADS)

Yuan, Han; Wang, Tianhong; Jiang, Yue; Li, Qiang; Wang, Guo-Li

2018-06-01

The existence of heavy meson lepton number violating (LNV) processes shows the Majorana nature of the neutrino. Much of this theoretical and experimental researche focuses on this type of decay. Four-body epton-number violation (LNV) processes of the B meson may have sizable branching ratios as they share the same vertex and mixing parameters with the three-body case. Mixing parameters between the heavy Majorana neutrino and charged leptons extracted from the three-body case can be used to constrain the branching ratios of four-body decays of the B meson. So we can update the upper limits of these mixing parameters with new experimental data of the three-body LNV decays. We also analyze {B}0\\to {D}* -{{\\ell }}1+{{\\ell }}2+{M}2- using the updated parameters and estimate some channels’ reconstruction events using current experimental data from Belle.

Experimental study of pp{eta} dynamics with WASA-at-COSY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shah, Neha

2011-10-24

To investigate the interaction of {eta}-meson with the nucleons, its production, near the kinematical threshold, in proton-proton collisions has been studied with the WASA detector at COSY storage ring in Juelich, Germany. The data has been taken at beam energy 1400 MeV (corresponding to excess energy (Q = 57 MeV). The {eta}-meson was detected via its 3{pi}{sup 0} decay in nearly 4{pi} detector and two protons were measured in forward direction. The determination of four vectors of both protons and the {eta}-meson in the final state allowed to derive complete kinematical information of the pp{eta}-system. The analysis resulted in 9x10{supmore » 6} events of {eta}{yields}3{pi}{sup 0} giving total production cross-section (8.87{+-}0.03{sub stat}{+-}2.57{sub sys}){mu}b. The angular distribution of {eta}-meson in the center of mass frame is anisotropic and squared invariant mass distributions for proton-proton and proton-{eta} shows deviation from pure phase space.« less

First Observation of Charmed Resonances in the $$\\Lambda^0_b \\to \\Lambda^+_c \\pi^- \\pi^+ \\pi^-$$ Inclusive Decay and Measurement of Their Relative Branching Ratios at CDF

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barria, Patrizia

2012-01-01

We present the observation of themore » $$\\Lambda^0_b$$ decay into a $$\\Lambda^+_c \\pi^- \\pi^+ \\pi^-$$ final state, in $$p\\bar{p}$$ collisions at $$\\sqrt{s}$$ = 1:96 TeV. The data analyzed were collected by the CDF II detector at the Fermilab Tevatron collider, and correspond to 2:4 $$fb^{-1}$$ of integrated luminosity. We fit the invariant mass distribution of the reconstructed candidates to extract a signal yield of 848 $$\\pm$$ 93 $$\\Lambda^0_b$$ into $$\\Lambda^+_c \\pi^- \\pi^+ \\pi^-$$....« less

piRNA-guided slicing of transposon transcripts enforces their transcriptional silencing via specifying the nuclear piRNA repertoire.

PubMed

Senti, Kirsten-André; Jurczak, Daniel; Sachidanandam, Ravi; Brennecke, Julius

2015-08-15

PIWI clade Argonaute proteins silence transposon expression in animal gonads. Their target specificity is defined by bound ∼23- to 30-nucleotide (nt) PIWI-interacting RNAs (piRNAs) that are processed from single-stranded precursor transcripts via two distinct pathways. Primary piRNAs are defined by the endonuclease Zucchini, while biogenesis of secondary piRNAs depends on piRNA-guided transcript cleavage and results in piRNA amplification. Here, we analyze the interdependencies between these piRNA biogenesis pathways in developing Drosophila ovaries. We show that secondary piRNA-guided target slicing is the predominant mechanism that specifies transcripts—including those from piRNA clusters—as primary piRNA precursors and defines the spectrum of Piwi-bound piRNAs in germline cells. Post-transcriptional silencing in the cytoplasm therefore enforces nuclear transcriptional target silencing, which ensures the tight suppression of transposons during oogenesis. As target slicing also defines the nuclear piRNA pool during mouse spermatogenesis, our findings uncover an unexpected conceptual similarity between the mouse and fly piRNA pathways. © 2015 Senti et al.; Published by Cold Spring Harbor Laboratory Press.

Meson electro-/photo-production from QCD

DOE PAGES

Briceno, Raul A.

2016-07-02

I present the calculation of themore » $$\\pi^+\\gamma^\\star\\to\\pi^+\\pi^0$$ transition amplitude from quantum chromodynamics performed by the Hadron Spectrum Collaboration. The amplitude is determined for a range of values of the photon virtuality and the final state energy. One observes a clear dynamical enhancement due to the presence of the $$\\rho$$ resonance. By fitting the transition amplitude and analytically continuing it onto the $$\\rho$$-pole, the $$\\rho\\to\\pi\\gamma^\\star$$ form factor is obtained. This exploratory calculation, performed using lattice quantum chromodynamics, constitutes the very first determination of an electroweak decay of a hadronic resonance directly from the fundamental theory of quarks and gluons. In this talk, I highlight some of the necessary steps that made this calculation possible, placing emphasis on recently developed formalism. In conclusion, I discuss the status and outlook of the field for the study of $$N\\gamma^\\star\\to N^\\star\\to N\\pi$$ transitions.« less

Measurements of the mass and width of the eta(c) meson and of an eta(c)(2S) candidate.

PubMed

Aubert, B; Barate, R; Boutigny, D; Gaillard, J-M; Hicheur, A; Karyotakis, Y; Lees, J P; Robbe, P; Tisserand, V; Zghiche, A; Palano, A; Pompili, A; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Ofte, I; Stugu, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Charles, E; Day, C T; Gill, M S; Gritsan, A V; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kolomensky, Yu G; Kral, J F; Kukartsev, G; LeClerc, C; Levi, M E; Lynch, G; Mir, L M; Oddone, P J; Orimoto, T J; Pripstein, M; Roe, N A; Romosan, A; Ronan, M T; Shelkov, V G; Telnov, A V; Wenzel, W A; Ford, K; Harrison, T J; Hawkes, C M; Knowles, D J; Morgan, S E; Penny, R C; Watson, A T; Watson, N K; Deppermann, T; Goetzen, K; Koch, H; Lewandowski, B; Pelizaeus, M; Peters, K; Schmuecker, H; Steinke, M; Barlow, N R; Boyd, J T; Chevalier, N; Cottingham, W N; Kelly, M P; Latham, T E; Mackay, C; Wilson, F F; Abe, K; Cuhadar-Donszelmann, T; Hearty, C; Mattison, T S; McKenna, J A; Thiessen, D; Kyberd, P; McKemey, A K; Blinov, V E; Bukin, A D; Golubev, V B; Ivanchenko, V N; Kravchenko, E A; Onuchin, A P; Serednyakov, S I; Skovpen, Yu I; Solodov, E P; Yushkov, A N; Best, D; Bruinsma, M; Chao, M; Kirkby, D; Lankford, A J; Mandelkern, M; Mommsen, R K; Roethel, W; Stoker, D P; Buchanan, C; Hartfiel, B L; Shen, B C; Del Re, D; Hadavand, H K; Hill, E J; MacFarlane, D B; Paar, H P; Rahatlou, Sh; Schwanke, U; Sharma, V; Berryhill, J W; Campagnari, C; Dahmes, B; Kuznetsova, N; Levy, S L; Long, O; Lu, A; Mazur, M A; Richman, J D; Verkerke, W; Beck, T W; Beringer, J; Eisner, A M; Heusch, C A; Lockman, W S; Schalk, T; Schmitz, R E; Schumm, B A; Seiden, A; Turri, M; Walkowiak, W; Williams, D C; Wilson, M G; Albert, J; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Hitlin, D G; Narsky, I; Porter, F C; Ryd, A; Samuel, A; Yang, S; Jayatilleke, S; Mancinelli, G; Meadows, B T; Sokoloff, M D; Abe, T; Blanc, F; Bloom, P; Chen, S; Clark, P J; Ford, W T; Nauenberg, U; Olivas, A; Rankin, P; Roy, J; Smith, J G; Van Hoek, W C; Zhang, L; Harton, J L; Hu, T; Soffer, A; Toki, W H; Wilson, R J; Zhang, J; Altenburg, D; Brandt, T; Brose, J; Colberg, T; Dickopp, M; Dubitzky, R S; Hauke, A; Lacker, H M; Maly, E; Müller-Pfefferkorn, R; Nogowski, R; Otto, S; Schubert, J; Schubert, K R; Schwierz, R; Spaan, B; Wilden, L; Bernard, D; Bonneaud, G R; Brochard, F; Cohen-Tanugi, J; Grenier, P; Thiebaux, Ch; Vasileiadis, G; Verderi, M; Khan, A; Lavin, D; Muheim, F; Playfer, S; Swain, J E; Tinslay, J; Andreotti, M; Azzolini, V; Bettoni, D; Bozzi, C; Calabrese, R; Cibinetto, G; Luppi, E; Negrini, M; Piemontese, L; Sarti, A; Treadwell, E; Anulli, F; Baldini-Ferroli, R; Biasini, M; Calcaterra, A; De Sangro, R; Falciai, D; Finocchiaro, G; Patteri, P; Peruzzi, I M; Piccolo, M; Pioppi, M; Zallo, A; Buzzo, A; Capra, R; Contri, R; Crosetti, G; Lo Vetere, M; Macri, M; Monge, M R; Passaggio, S; Patrignani, C; Robutti, E; Santroni, A; Tosi, S; Bailey, S; Morii, M; Won, E; Bhimji, W; Bowerman, D A; Dauncey, P D; Egede, U; Eschrich, I; Gaillard, J R; Morton, G W; Nash, J A; Sanders, P; Taylor, G P; Grenier, G J; Lee, S-J; Mallik, U; Cochran, J; Crawley, H B; Lamsa, J; Meyer, W T; Prell, S; Rosenberg, E I; Yi, J; Davier, M; Grosdidier, G; Höcker, A; Laplace, S; Le Diberder, F; Lepeltier, V; Lutz, A M; Petersen, T C; Plaszczynski, S; Schune, M H; Tantot, L; Wormser, G; Brigljević, V; Cheng, C H; Lange, D J; Wright, D M; Bevan, A J; Coleman, J P; Fry, J R; Gabathuler, E; Gamet, R; Kay, M; Parry, R J; Payne, D J; Sloane, R J; Touramanis, C; Back, J J; Harrison, P F; Shorthouse, H W; Strother, P; Vidal, P B; Brown, C L; Cowan, G; Flack, R L; Flaecher, H U; George, S; Green, M G; Kurup, A; Marker, C E; McMahon, T R; Ricciardi, S; Salvatore, F; Vaitsas, G; Winter, M A; Brown, D; Davis, C L; Allison, J; Barlow, R J; Forti, A C; Hart, P A; Jackson, F; Lafferty, G D; Lyon, A J; Weatherall, J H; Williams, J C; Farbin, A; Jawahery, A; Kovalskyi, D; Lae, C K; Lillard, V; Roberts, D A; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Koptchev, V B; Moore, T B; Saremi, S; Staengle, H; Willocq, S; Cowan, R; Sciolla, G; Taylor, F; Yamamoto, R K; Mangeol, D J J; Milek, M; Patel, P M; Lazzaro, A; Palombo, F; Bauer, J M; Cremaldi, L; Eschenburg, V; Godang, R; Kroeger, R; Reidy, J; Sanders, D A; Summers, D J; Zhao, H W; Brunet, S; Cote-Ahern, D; Hast, C; Taras, P; Nicholson, H; Cartaro, C; Cavallo, N; De Nardo, G; Fabozzi, F; Gatto, C; Lista, L; Paolucci, P; Piccolo, D; Sciacca, C; Baak, M A; Raven, G; LoSecco, J M; Gabriel, T A; Brau, B; Gan, K K; Honscheid, K; Hufnagel, D; Kagan, H; Kass, R; Pulliam, T; Wong, Q K; Brau, J; Frey, R; Potter, C T; Sinev, N B; Strom, D; Torrence, E; Colecchia, F; Dorigo, A; Galeazzi, F; Margoni, M; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Tiozzo, G; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; de la Vaissière, Ch; Del Buono, L; Hamon, O; John, M J J; Leruste, Ph; Ocariz, J; Pivk, M; Roos, L; Stark, J; T'Jampens, S; Therin, G; Manfredi, P F; Re, V; Behera, P K; Gladney, L; Guo, Q H; Panetta, J; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Bucci, F; Calderini, G; Carpinelli, M; Forti, F; Giorgi, M A; Lusiani, A; Marchiori, G; Martinez-Vidal, F; Morganti, M; Neri, N; Paoloni, E; Rama, M; Rizzo, G; Sandrelli, F; Walsh, J; Haire, M; Judd, D; Paick, K; Wagoner, D E; Danielson, N; Elmer, P; Lu, C; Miftakov, V; Olsen, J; Smith, A J S; Tanaka, H A; Varnes, E W; Bellini, F; Cavoto, G; Faccini, R; Ferrarotto, F; Ferroni, F; Gaspero, M; Mazzoni, M A; Morganti, S; Pierini, M; Piredda, G; Safai Tehrani, F; Voena, C; Christ, S; Wagner, G; Waldi, R; Adye, T; De Groot, N; Franek, B; Geddes, N I; Gopal, G P; Olaiya, E O; Xella, S M; Aleksan, R; Emery, S; Gaidot, A; Ganzhur, S F; Giraud, P-F; Hamel de Monchenault, G; Kozanecki, W; Langer, M; Legendre, M; London, G W; Mayer, B; Schott, G; Vasseur, G; Yeche, Ch; Zito, M; Purohit, M V; Weidemann, A W; Yumiceva, F X; Aston, D; Bartoldus, R; Berger, N; Boyarski, A M; Buchmueller, O L; Convery, M R; Coupal, D P; Dong, D; Dorfan, J; Dujmic, D; Dunwoodie, W; Field, R C; Glanzman, T; Gowdy, S J; Grauges-Pous, E; Hadig, T; Halyo, V; Hryn'ova, T; Innes, W R; Jessop, C P; Kelsey, M H; Kim, P; Kocian, M L; Langenegger, U; Leith, D W G S; Luitz, S; Luth, V; Lynch, H L; Marsiske, H; Messner, R; Muller, D R; O'Grady, C P; Ozcan, V E; Perazzo, A; Perl, M; Petrak, S; Ratcliff, B N; Robertson, S H; Roodman, A; Salnikov, A A; Schindler, R H; Schwiening, J; Simi, G; Snyder, A; Soha, A; Stelzer, J; Su, D; Sullivan, M K; Va'vra, J; Wagner, S R; Weaver, M; Weinstein, A J R; Wisniewski, W J; Wright, D H; Young, C C; Burchat, P R; Edwards, A J; Meyer, T I; Petersen, B A; Roat, C; Ahmed, S; Alam, M S; Ernst, J A; Saleem, M; Wappler, F R; Bugg, W; Krishnamurthy, M; Spanier, S M; Eckmann, R; Kim, H; Ritchie, J L; Schwitters, R F; Izen, J M; Kitayama, I; Lou, X C; Ye, S; Bianchi, F; Bona, M; Gallo, F; Gamba, D; Borean, C; Bosisio, L; Della Ricca, G; Dittongo, S; Grancagnolo, S; Lanceri, L; Poropat, P; Vitale, L; Vuagnin, G; Panvini, R S; Banerjee, Sw; Brown, C M; Fortin, D; Jackson, P D; Kowalewski, R; Roney, J M; Band, H R; Dasu, S; Datta, M; Eichenbaum, A M; Johnson, J R; Kutter, P E; Li, H; Liu, R; Di Lodovico, F; Mihalyi, A; Mohapatra, A K; Pan, Y; Prepost, R; Sekula, S J; von Wimmersperg-Toeller, J H; Wu, J; Wu, S L; Yu, Z; Neal, H

2004-04-09

The mass m(eta(c)) and total width Gamma(eta(c))(tot) of the eta(c) meson have been measured in two-photon interactions at the SLAC e(+)e(-) asymmetric B Factory with the BABAR detector. With a sample of approximately 2500 reconstructed eta(c)-->K(0)(S)K+/-pi(-/+) decays in 88 fb(-1) of data, the results are m(eta(c))=2982.5+/-1.1(stat)+/-0.9(syst) MeV/c(2) and Gamma(eta(c))(tot)=34.3+/-2.3(stat)+/-0.9(syst) MeV/c(2). Using the same decay mode, a second resonance with 112+/-24 events is observed with a mass of 3630.8+/-3.4(stat)+/-1.0(syst) MeV/c(2) and width of 17.0+/-8.3(stat)+/-2.5(syst) MeV/c(2). This observation is consistent with expectations for the eta(c)(2S) state.

Evaluating the performance of PI-RADS v2 in the non-academic setting.

PubMed

Jordan, Eric J; Fiske, Charles; Zagoria, Ronald J; Westphalen, Antonio C

2017-11-01

To evaluate the utility of PI-RADS v2 to diagnose clinically significant prostate cancer (CS-PCa) with magnetic resonance ultrasound (MR/US) fusion-guided prostate biopsies in the non-academic setting. Retrospective analysis of men whom underwent prostate multiparametric MRI and subsequent MR/US fusion biopsies at a single non-academic center from 11/2014 to 3/2016. Prostate MRIs were performed on a 3-Tesla scanner with a surface body coil. The Prostate Imaging Reporting and Data System (PI-RADS) v2 scoring algorithm was utilized and MR/US fusion biopsies were performed in selected cases. Mixed effect logistic regression analyses and receiver-operating characteristic (ROC) curves were performed on PI-RADS v2 alone and combined with PSA density (PSAD) to predict CS-PCa. 170 patients underwent prostate MRI with 282 PI-RADS lesions. MR/US fusion diagnosed 71 CS-PCa, 33 Gleason score 3+3, and 168 negative. PI-RADS v2 score is a statistically significant predictor of CS-PCa (P < 0.001). For each one-point increase in the overall PI-RADS v2 score, the odds of having CS-PCa increases by 4.2 (95% CI 2.2-8.3). The area under the ROC curve for PI-RADS v2 is 0.69 (95% CI 0.63-0.76) and for PI-RADS v2 + PSAD is 0.76 (95% CI 0.69-0.82), statistically higher than PI-RADS v2 alone (P < 0.001). The rate of CS-PCa was about twice higher in men with high PSAD (≥0.15) compared to men with low PSAD (<0.15) when a PI-RADS 4 or 5 lesion was detected (P = 0.005). PI-RADS v2 is a strong predictor of CS-PCa in the non-academic setting and can be further strengthened when utilized with PSA density.

PI3K pathway inhibitors: potential prospects as adjuncts to vaccine immunotherapy for glioblastoma.

PubMed

Oh, Taemin; Ivan, Michael E; Sun, Matthew Z; Safaee, Michael; Fakurnejad, Shayan; Clark, Aaron J; Sayegh, Eli T; Bloch, Orin; Parsa, Andrew T

2014-01-01

Constitutive activation of the PI3K pathway has been implicated in glioblastoma (GBM) pathogenesis. Pharmacologic inhibition can both inhibit tumor survival and downregulate expression of programmed death ligand-1, a protein highly expressed on glioma cells that strongly contributes to cancer immunosuppression. In that manner, PI3K pathway inhibitors can help optimize GBM vaccine immunotherapy. In this review, we describe and assess the potential integration of various classes of PI3K pathway inhibitors into GBM immunotherapy. While early-generation inhibitors have a wide range of immunosuppressive effects that could negate their antitumor potency, further work should better characterize how contemporary inhibitors affect the immune response. This will help determine if these inhibitors are truly a therapeutic avenue with a strong future in GBM immunotherapy.

Hadronic decays of the X(3872) to {chi}{sub cJ} in effective field theory

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fleming, Sean; Mehen, Thomas

2008-11-01

The decays of the X(3872) to P-wave quarkonia are calculated under the assumption that it is a shallow bound state of neutral charmed mesons. The X(3872) is described using an effective theory of nonrelativistic D mesons and pions (X-EFT). We calculate X(3872) decays by first matching heavy hadron chiral perturbation theory (HH{chi}PT) amplitudes for D{sup 0}D*{sup 0}{yields}{chi}{sub cJ}({pi}{sup 0},{pi}{pi}) onto local operators in X-EFT, and then using these operators to calculate the X(3872) decays. This procedure reproduces the factorization theorems for X(3872) decays to conventional quarkonia previously derived using the operator product expansion. For single pion decays, we find nontrivialmore » dependence on the pion energy from HH{chi}PT diagrams with virtual D mesons. This nontrivial energy dependence can potentially modify heavy-quark symmetry predictions for the relative sizes of decay rates. At leading order, decays to final states with two pions are dominated by the final state {chi}{sub c1}{pi}{sup 0}{pi}{sup 0}, with a branching fraction just below that for the decay to {chi}{sub c1}{pi}{sup 0}. Decays to all other final states with two pions are highly suppressed.« less

Light-front holographic distribution amplitudes of pseudoscalar mesons and their application to B -meson decays

DOE PAGES

Chang, Qin; Brodsky, Stanley J.; Li, Xin-Qiang

2017-05-30

In this article the dynamical spin effects of the light-front holographic wave functions for light pseudoscalar mesons are studied. These improved wave functions are then confronted with a number of hadronic observables: the decay constants of π and K mesons, their ξ -moments, the pion-to-photon transition form factor, and the pure annihilationmore » $$\\bar{B}_s$$ → π + π - and $$\\bar{B}_d$$ → K + K - decays. Taking f π , fK , and their ratio fK / f π as constraints, we perform a χ 2 analysis for the holographic parameters, including the mass scale parameter $$\\sqrtλ$$ and the effective quark masses, and find that the fitted results are quite consistent with the ones obtained from the light-quark hadronic Regge trajectories. In addition, we also show that the end point divergence appearing in the pure annihilation $$\\bar{B}_s$$ → π + π - and $$\\bar{B}_d$$ → K + K - decays can be controlled well by using these improved light-front holographic distribution amplitudes.« less

Negative-mass mitigation of Coulomb repulsion for terahertz undulator radiation of electron bunches

DOE Office of Scientific and Technical Information (OSTI.GOV)

Balal, N.; Magory, E.; Bandurkin, I. V.

2015-10-19

It is proposed to utilize the effect of negative mass for stabilization of the effective axial size of very dense and short electron bunches produced by photo-injector guns by using combined undulator and strong uniform magnetic fields. It has been shown that in the “abnormal” regime, an increase in the electron energy leads to a decrease in the axial velocity of the electron; due to the negative-mass effect, the Coulomb repulsion of electrons leads to their attraction and formation of a fairly stable and compact bunch “nucleus.” An undulator with a strong uniform magnetic field providing the negative-mass effect ismore » designed for an experimental source of terahertz radiation. The use of the negative-mass regime in this experiment should result in a long-pulse coherent spontaneous undulator emission from a short dense moderately relativistic (5.5 MeV) photo-injector electron bunch with a high (up to 20%) efficiency and a narrow frequency spectrum.« less

Treating Radiation Induced Skin Injury and Fibrosis Using Small Molecule Thiol Modifying Agents

DTIC Science & Technology

2016-10-01

experimental groups were designed as follows: i) Radiation/RTA408 (6 mg/kg) administered on days 1,2,3,4,5 post-radiation; ii) Radiation/DMSO...Collaborating Organizations: Name: Adam Luginbuhl Project role: PI Contribution to Project Design , experimental support, analysis Funding Support...Clinical and DOD grant Name: Ulrich Rodeck Project role: Co-PI Contribution to Project Design , experimental support, analysis Funding Support DOD

Mass spectra and decay properties of the c\\bar{c} meson

NASA Astrophysics Data System (ADS)

Chaturvedi, Raghav; Kumar Rai, Ajay

2018-06-01

In this article we present the result of c\\bar{c} meson mass calculation by solving the Schrödinger equation numerically considering the Coulomb plus linear potential. The spin-hyperfine, spin-orbit and tensor components of one-gluon-exchange interactions are employed to obtain the mass spectra of c\\bar{c} meson. The calculated mass spectra are compared with the latest results of PDG and are found to be in good accordance. The Regge trajectories of the calculated mass spectra have also been constructed. The values of the wave function are extracted and employed to calculate the leptonic decay constant, γγ, gg, e+e-, light hadron (LH) and γγγ decay widths of S-wave 0^{-+} and 1^{- -} states of c\\bar{c} meson, the widths have been calculated by Van Royen-Weisskopf formula and by NRQCD mechanism incorporating relativistic corrections of order ν2. The γγ and gg decay widths of χ0 and χ2 states of c\\bar{c} meson have also been calculated. The calculated decay constants and widths have been compared with the experimental results.

Measurements of total production cross sections for $$\\pi^{+}$$+C, $$\\pi^{+}$$+Al, $$K^{+}$$+C, and $$K^{+}$$+Al at 60 GeV/c and $$\\pi^{+}$$+C and $$\\pi^{+}$$+Al at 31 GeV/c

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aduszkiewicz, A.; et al.

This paper presents several measurements of total production cross sections and total inelastic cross sections for the following reactions:more » $$\\pi^{+}$$+C, $$\\pi^{+}$$+Al, $$K^{+}$$+C, $$K^{+}$$+Al at 60 GeV/c, $$\\pi^{+}$$+C and $$\\pi^{+}$$+Al at 31 GeV/c . The measurements were made using the NA61/SHINE spectrometer at the CERN SPS. Comparisons with previous measurements are given and good agreement is seen. These interaction cross sections measurements are a key ingredient for neutrino flux prediction from the reinteractions of secondary hadrons in current and future accelerator-based long-baseline neutrino experiments.« less

Result and perspectives on meson spectroscopy with KLOE and KLOE-2

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taccini, Cecilia

2013-10-21

From 2000 to 2006 KLOE has collected 2.5 fb{sup −1} of e{sup +}e{sup −} collisions at the peak of the φ(1020) and 250 pb{sup −1} off-peak. In this paper the most recent results on meson spectroscopy are presented, with emphasis on rare eta meson decays, the search for the U boson, and γγ collisions.

Study of a Narrow {pi}{sup +{pi}-} Peak at about 755 MeV/c{sup 2} in p-barn{yields}2{pi}{sup +}3{pi}{sup -} Annihilation at Rest

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gaspero, Mario

2010-08-05

A narrow peak in the {pi}{sup +{pi}-} mass distribution was seen by the Rome-Syracuse Collaboration in p-barn{yields}2{pi}{sup +}3{pi}{sup -} annihilation at rest in 1970. It was ignored for 40 years. The reanalysis of this peak finds that it has the mass 757.4{+-}2.8{sub stat{+-}}1.2{sub sys} MeV/c{sup 2} and a width consistent with the experimental resolution. The evidence of the peak is 5.2 standard deviations. The peak is generated in (1.03{+-}0.21{sub stat{+-}}0.21{sub sys})% of the p-barn annihilations at rest. No spin analysis is possible with the statistics of the experiment but there are arguments suggesting that it has J{sup p} = 0{supmore » +}.« less

Vector Mesons in Cold Nuclear Matter

NASA Astrophysics Data System (ADS)

Rodrigues, Tulio E.; Dias de Toledo Arruda-Neto, Joāo

2013-03-01

The attenuation of vector mesons in cold nuclear matter is studied through the mechanism of incoherent photoproduction off complex nuclei. The latter is described via the time-dependent multi-collisional Monte Carlo (MCMC) intranuclear cascade model. The results for the transparency ratios of ω mesons reproduce previous measurements of CB-ELSA/TAPS with an inelastic ωN cross section around 40 mb for ρω ~ 1.1 GeV/c. The corresponding in-medium width (nuclear rest frame) is extracted dinamically from the algorithm and depends on the average nuclear density pN and target nucleus: ~ 49.2 MeV/c2 for carbon (pN 0.114 far-3) and ~ 77.3 MeV/c2 for lead (pN 0.137 far--3). The calculations fail to reproduce the huge absorption observed at JLab assuming the same inelastic cross section and the discrepancy between the two experiments remains a challenge.

Consequences of Widespread Piñon Mortality for Water Availability and Water Use Dynamics in Piñon-Juniper Woodlands

NASA Astrophysics Data System (ADS)

Morillas, L.; Pangle, R. E.; Krofcheck, D. J.; Pockman, W.; Litvak, M. E.

2014-12-01

Tree die-off events have showed a rapid increase in the last decade as a result of warmer temperatures and more severe drought. In the southwestern US, where piñon-juniper (PJ) woodlands occupy 24 million ha, the turn of the century drought (1999-2002) triggered 40-95% mortality of piñon pine (Pinus edulis) and 2-25% mortality of juniper (Juniperous monosperma). To determine the consequences of this disturbance on surface water balance we conducted a girdling experiment where all piñon trees above 7 cm of diameter at breast height in an area of 200 m2 were girdled in September 2009. We compared water and energy fluxes in this girdled site (PJG) using open-path eddy covariance (EC) to fluxes measured simultaneously in an intact PJ woodland less than 3 km away (PJC). In addition to evapotranspiration (ET) measurements from EC, canopy transpiration (ETc) was measured using sap flow probes (Granier thermal dissipation method) installed on five juniper and five piñon trees at each site. Soil water content (SWC) was also monitored using TDR probes (CS610, Campbell Scientific) under the three main cover types ( bare soil, under juniper and under piñon) and at three depths (5,10 and 30 cm depths) in both sites. Total ET at PJG decreased slowly, but progressively, relative to PJC following the girdling, with annual ET 5%, 10% and 19% lower in 2010, 2011 and 2012, respectively, in the girdled site. Following the girdling, canopy transpiration was significantly reduced at PJG, with an observed reduction of annual ETc at PJG of 45%, 59% and 71% from 2010 to 2012 compared to the PJC site. Our results suggest that girdling triggered a significant increase of soil evaporation and understory transpiration (not directly measured) as a result of canopy cover loss. This agrees with significant higher establishment of annual forbs seen at PJG relative to PJC and the increase of solar radiation reaching the soil surface as a result of canopy cover loss. Our results suggest pi

Decreased expression of GST pi is correlated with a poor prognosis in human esophageal squamous carcinoma

PubMed Central

2010-01-01

Background Glutathione S-transferase pi (GST pi) is a subgroup of GST family, which provides cellular protection against free radical and carcinogenic compounds due to its detoxifying function. Expression patterns of GST pi have been studied in several carcinomas and its down-regulation was implicated to be involved in malignant transformation in patients with Barrett's esophagus. However, neither the exact role of GST pi in the pathogenesis nor its prognostic impact in squamous esophageal carcinoma is fully characterized. Methods Immunohistochemistry was used to investigate GST pi expression on 153 archival squamous esophageal carcinoma specimens with a GST pi monoclonal antibody. Statistic analyses were performed to explore its association with clinicopathological factors and clinical outcome. Results The GST pi expression was greatly reduced in tissues of esophageal carcinomas compared to adjacent normal tissues and residual benign tissues. Absent of GST pi protein expression in cytoplasm, nuclear and cytoplasm/nucleus was found in 51%, 64.7% and 48% of all the carcinoma cases, respectively. GST pi deficiency in cytoplasm, nucleus and cytoplasm/nucleus was significantly correlated to poor differentiation (p < 0.001, p < 0.001 and p < 0.001, respectively). UICC stage and T stage were found significantly correlated to negative expression of GST pi in cytoplasm (p < 0.001 and p = 0.004, respectively) and cytoplasm/nucleus (p = 0.017 and p = 0.031, respectively). In univariate analysis, absent of GST pi protein expression in cytoplasm, nucleus and cytoplasm/nucleus was significantly associated with a shorter overall survival (p < 0.001, p < 0.001 and p < 0.001, respectively), whereas only GST pi cytoplasmic staining retained an independent prognostic significance (p < 0.001) in multivariate analysis. Conclusions Our results show that GST pi expression is down regulated in the squamous esophageal carcinoma, and that the lack of GST pi expression is associated with

PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells.

PubMed

Li, Jiangmei; Gao, Zhen; Zhao, Dan; Zhang, Lunfeng; Qiao, Xinhua; Zhao, Yingying; Ding, Hong; Zhang, Panpan; Lu, Junyan; Liu, Jia; Jiang, Hualiang; Luo, Cheng; Chen, Chang

2017-11-15

While phosphatidylinositol 4-kinase (PI4KIIα) has been identified as a potential target for antitumor therapy, the clinical applications of PI4KIIα are limited by a lack of specific inhibitors. Here we report the first small-molecule inhibitor (SMI) of human PI4KIIα. Docking-based and ligand-based virtual screening strategies were first employed to identify promising hits, followed by two rounds of kinase activity inhibition validation. 2-(3-(4-Chlorobenzoyl)thioureido)-4-ethyl-5-methylthiophene-3-carboxamide (PI-273) exhibited the greatest inhibitory effect on PI4KIIα kinase activity (IC 50 = 0.47 μmol/L) and suppressed cell proliferation. Surface plasmon resonance and thermal shift assays indicated that PI-273 interacted directly with PI4KIIα. Kinetic analysis identified PI-273 as a reversible competitive inhibitor with respect to the substrate phosphatidylinositol (PI), which contrasted with most other PI kinase inhibitors that bind the ATP binding site. PI-273 reduced PI4P content, cell viability, and AKT signaling in wild-type MCF-7 cells, but not in PI4KIIα knockout MCF-7 cells, indicating that PI-273 is highly selective for PI4KIIα. Mutant analysis revealed a role of palmitoylation insertion in the selectivity of PI-273 for PI4KIIα. In addition, PI-273 treatment retarded cell proliferation by blocking cells in G 2 -M, inducing cell apoptosis and suppressing colony-forming ability. Importantly, PI-273 significantly inhibited MCF-7 cell-induced breast tumor growth without toxicity. PI-273 is the first substrate-competitive, subtype-specific inhibitor of PI4KIIα, the use of which will facilitate evaluations of PI4KIIα as a cancer therapeutic target. Cancer Res; 77(22); 6253-66. ©2017 AACR . ©2017 American Association for Cancer Research.

ϕ Meson Production at Forward Rapidity with the PHENIX Detector at RHIC

NASA Astrophysics Data System (ADS)

Sarsour, Murad

2017-12-01

The ϕ meson production in p+p collisions is an important tool to study QCD, providing data to tune phenomenological QCD models, while in high-energy heavy-ion collisions it provides key information on the hot and dense state of the strongly interacting matter produced in such collisions. It is sensitive to the medium-induced effects such as strangeness enhancement, a phenomenon associated with soft particles in bulk matter. Measurements in the dilepton channels are especially interesting since leptons interact only electromagnetically, thus carrying the information from their production phase directly to the detector. Measurements in different nucleus-nucleus collisions allow us to perform a systematic study of the nuclear medium effects on ϕ meson production. The PHENIX detector provides the capabilities to measure the ϕ meson production in a wide range of transverse momentum and rapidity to study various cold nuclear effects such as soft multiple parton rescattering and modification of the parton distribution functions in nuclei. In this proceeding, we report the most recent PHENIX results on ϕ meson production in p+p, d+Au and Cu+Au collisions.

Dispersion relations with crossing symmetry for {pi}{pi}D- and F1-wave amplitudes

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kaminski, R.

Results of implementation of dispersion relations with imposed crossing symmetry condition to description of {pi}{pi}D and F1 wave amplitudes are presented. We use relations with only one subtraction what leads to small uncertainties of results and to strong constraints for tested {pi}{pi} amplitudes. Presented equations are similar to those with one subtraction (so called GKPY equations) and to those with two subtractions (the Roy's equations) for the S and P waves. Numerical calculations are done with the S and P wave input amplitudes tested already with use of the Roy's and GKPY equations.

Exclusive photoproduction of vector mesons in proton-lead ultraperipheral collisions at the LHC

NASA Astrophysics Data System (ADS)

Xie, Ya-Ping; Chen, Xurong

2018-02-01

Rapidity distributions of vector mesons are computed in dipole model proton-lead ultraperipheral collisions (UPCs) at the CERN Larger Hadron Collider (LHC). The dipole model framework is implemented in the calculations of cross sections in the photon-hadron interaction. The bCGC model and Boosted Gaussian wave functions are employed in the scattering amplitude. We obtain predictions of rapidity distributions of J / ψ meson proton-lead ultraperipheral collisions. The predictions give a good description to the experimental data of ALICE. The rapidity distributions of ϕ, ω and ψ (2 s) mesons in proton-lead ultraperipheral collisions are also presented in this paper.

Unusual pi-donating effects of pi-accepting substituents on the stabilities of benzylic cations: a theoretical study.

PubMed

Kim, Chang Kon; Han, In Suk; Ryu, Wang Sun; Lee, Hai Whang; Lee, Bon-Su; Kim, Chan Kyung

2006-02-23

The pi-donating effects of pi-accepting X-substituents in substituted benzylic cations, X-C(6)H(5)-CHR(+) where R = CF(3), H and OCH(3), and X = p-NH(2), p-OCH(3), p-CH(3), H, p-F, p-Cl, p-CHO, m-CN, p-CN, m-NO(2) or p-NO(2), have been studied theoretically by using isodesmic hydride transfer reactions at various levels of theory. It might be difficult to determine the pi-donating effects of pi-acceptors using the simple Hammett-type linear equation, because it is not sensitive enough to include small pi-donating effects. Therefore, this effect was estimated using the NBO deletion energy (DeltaE(D)) of the second-order charge-transfer interaction (DeltaE(ct)) between the pi-orbitals (or lone pair orbitals) of the X-substituent and the pi-orbitals of phenyl ring. The extents of pi-donating effects increased in the order X = p-NO(2) < p-CHO < p-CN < p-Cl for both neutral and cationic species, and these effects were found to be more important for para- than for meta-substituents. Moreover, this could represent a general trend for pi-donation by pi-acceptors. On the other hand, the effects of R-substituents on this pi-donating effect were found to be in the order R = OCH(3) < H congruent with CF(3), as predicted by natural resonance theory (NRT) analyses.

Effective chiral restoration in the ρ' meson in lattice QCD

NASA Astrophysics Data System (ADS)

Glozman, L. Ya.; Lang, C. B.; Limmer, Markus

2010-11-01

In simulations with dynamical quarks it has been established that the ground state ρ in the infrared is a strong mixture of the two chiral representations (0,1)+(1,0) and (1/2,1/2)b. Its angular momentum content is approximately the S13 partial wave. Effective chiral restoration in an excited ρ-meson would require that in the infrared this meson couples predominantly to one of the two representations. The variational method allows one to study the mixing of interpolators with different chiral transformation properties in the nonperturbatively determined excited state at different resolution scales. We present results for the first excited state of the ρ-meson using simulations with nf=2 dynamical quarks. We point out, that in the infrared a leading contribution to ρ'=ρ(1450) comes from (1/2,1/2)b, in contrast to the ρ. The ρ' wave function contains a significant contribution of the D13 wave which is not consistent with the quark model prediction.

Discrete symmetries with neutral mesons

NASA Astrophysics Data System (ADS)

Bernabéu, José

2018-01-01

Symmetries, and Symmetry Breakings, in the Laws of Physics play a crucial role in Fundamental Science. Parity and Charge Conjugation Violations prompted the consideration of Chiral Fields in the construction of the Standard Model, whereas CP-Violation needed at least three families of Quarks leading to Flavour Physics. In this Lecture I discuss the Conceptual Basis and the present experimental results for a Direct Evidence of Separate Reversal-in-Time T, CP and CPT Genuine Asymmetries in Decaying Particles like Neutral Meson Transitions, using Quantum Entanglement and the Decay as a Filtering Measurement. The eight transitions associated to the Flavour-CP eigenstate decay products of entangled neutral mesons have demonstrated with impressive significance a separate evidence of TRV and CPV in Bd-physics, whereas a CPTV asymmetry shows a 2σ effect interpreted as an upper limit. Novel CPTV observables are discussed for K physics at KLOE-2, including the difference between the semileptonic asymmetries from KL and KS, the ratios of double decay rate Intensities to Flavour-CP eigenstate decay products and the ω-effect. Their observation would lead to a change of paradigm beyond Quantum Field Theory, however there is nothing in Quantum Mechanics forbidding CPTV.

Glutathione S-transferase Pi expression in invasive breast cancer and its relation with the clinical outcome.

PubMed

Franco, R L; Schenka, N G M; Schenka, A A A; Rezende, L F; Gurgel, M S C

2012-01-01

Glutathione S-transferase (GST) is a cytosolic enzymatic system involved in cellular detoxifying process. In vitro studies have shown that the presence of this enzymatic system in breast carcinoma cells can accelerate the elimination of drugs commonly used in chemotherapy, thereby decreasing its efficacy. The aim of the present study was to evaluate the association between GST Pi expression by breast carcinoma cells and disease-free and overall survival. Ninety-five female patients with invasive breast carcinoma submitted to surgical treatment and adjuvant chemotherapy from January, 1995 to June, 1997 and followed until August, 2006 were evaluated. The expression of GST Pi in breast carcinoma cells, determined by immunohistochemistry, was correlated with several clinical and pathological parameters of prognostic significance. There were 36 (37.9%) GST Pi-positive cases. GST Pi immunoexpression was not significantly correlated with patient's age, histological tumor type, clinical stage, hormone receptor status and survival. On the other hand, GST Pi positivity showed a significant correlation with a lower histological grade/C-erb-B2 negative breast carcinoma phenotype. The findings suggest that GST Pi expression does not constitute a satisfactory prognostic factor in breast cancer.

Vector mesons in the Nambu-Jona-Lasinio model

NASA Astrophysics Data System (ADS)

Schüren, C.; Döring, F.; Ruiz Arriola, E.; Goeke, K.

1993-12-01

We investigate solitonic solutions with baryon number equal to one of the semi-bosonized SU(2) Nambu-Jona-Lasinio model including σ -, π -, ρ -, A 1- and ω-mesons both on the chiral circle ( σ2r) + π2( r) = f2π) and beyond it ( σ2( r) + π2( r) ≠ f2π). The action is treated in the mesonic and baryonic sector in the leading order of the large- Nc expansion (one-quark-loop approximation). The UV-divergent real part of the effective action is rendered finite using different gauge-invariant regularization methods (Pauli-Villars and proper time). The parameters of the model are fixed in two different ways: either approximately by a heat kernel expansion of the effective action up to second order or by an exact calculation of the mesonic on-shell masses. This leaves the constituent quark mass as the only free parameter of the model. In the solitonic sector we pay special attention to the way the Wick rotation from euclidean space back to Minkowski space has to be performed. We get solitonic solutions from hedgehoglike field configurations on the chiral circle for a wide range of couplings. We also find that if the chiral-circle constraint is relaxed vector mesons provide stable solitonic solutions. Moreover, whether the baryon number is carried by the valence quarks or by the Dirac sea depends strongly on the particular values of the constituent quark mass. We also study the low-energy limit of the model and its connection to chiral perturbation theory. To this end a covariant-derivative expansion is performed in the presence of external fields. After integrating out the scalar, vector and axial degrees of freedom this leads to the corresponding low-energy parameters as e.g. pion radii and some threshold parameters for pion-pion scattering. Vector mesons provide a natural explanation for an axial coupling constant at the quark level gAQ lower than one. However, we find for the gAN of the nucleon noticeable deviations from the non-relativistic quark model

Increased PI3-kinase in presympathetic brain areas of the spontaneously hypertensive rat.

PubMed

Veerasingham, Shereeni J; Yamazato, Masanobu; Berecek, Kathleen H; Wyss, J Michael; Raizada, Mohan K

2005-02-18

Existing evidence led us to hypothesize that increases in p85alpha, a regulatory subunit of PI3-kinase, in presympathetic brain areas contribute to hypertension. PI3-kinase p85alpha, p110alpha, and p110delta mRNA was 1.5- to 2-fold higher in the paraventricular nucleus (PVN) of spontaneously hypertensive rats (SHR) compared with their controls, Wistar Kyoto rats (WKY). The increase in p85alpha/p110delta was attenuated in SHR treated with captopril, an angiotensin (Ang)-converting enzyme inhibitor, from in utero to 6 months of age. In the rostral ventrolateral medulla (RVLM), p110delta mRNA was approximately 2-fold higher in SHR than in WKY. Moreover, the increases in mRNA were associated with higher PI3-kinase activity in both nuclei. The functional relevance was studied in neuronal cultures because SHR neurons reflect the augmented p85alpha mRNA and PI3-kinase activity. Expression of a p85 dominant-negative mutant decreased norepinephrine (NE) transporter mRNA and [3H]NE uptake by approximately 60% selectively in SHR neurons. In summary, increased p85alpha/p110delta expression in the PVN and RVLM is associated with increased PI3-kinase activity in the SHR. Furthermore, normalized PI3-kinase p85alpha/p110delta expression within the PVN might contribute to the overall effect of captopril, perhaps attributable to a consequent decrease in NE availability.

PI(5)P Regulates Autophagosome Biogenesis

PubMed Central

Vicinanza, Mariella; Korolchuk, Viktor I.; Ashkenazi, Avraham; Puri, Claudia; Menzies, Fiona M.; Clarke, Jonathan H.; Rubinsztein, David C.

2015-01-01

Summary Phosphatidylinositol 3-phosphate (PI(3)P), the product of class III PI3K VPS34, recruits specific autophagic effectors, like WIPI2, during the initial steps of autophagosome biogenesis and thereby regulates canonical autophagy. However, mammalian cells can produce autophagosomes through enigmatic noncanonical VPS34-independent pathways. Here we show that PI(5)P can regulate autophagy via PI(3)P effectors and thereby identify a mechanistic explanation for forms of noncanonical autophagy. PI(5)P synthesis by the phosphatidylinositol 5-kinase PIKfyve was required for autophagosome biogenesis, and it increased levels of PI(5)P, stimulated autophagy, and reduced the levels of autophagic substrates. Inactivation of VPS34 impaired recruitment of WIPI2 and DFCP1 to autophagic precursors, reduced ATG5-ATG12 conjugation, and compromised autophagosome formation. However, these phenotypes were rescued by PI(5)P in VPS34-inactivated cells. These findings provide a mechanistic framework for alternative VPS34-independent autophagy-initiating pathways, like glucose starvation, and unravel a cytoplasmic function for PI(5)P, which previously has been linked predominantly to nuclear roles. PMID:25578879

{pi}-{pi} Interactions and magnetic properties in a series of hybrid inorganic-organic crystals

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gonzalez, M.; Lemus-Santana, A.A.; Rodriguez-Hernandez, J.

The series of hybrid inorganic-organic solids T(Im){sub 2}[Ni(CN){sub 4}] with T=Fe, Co, Ni and Im=imidazole were prepared by soft chemical routes from aqueous solutions of the involved building units: imidazole, T{sup 2+} metal and the [Ni(CN){sub 4}]{sup 2-} anionic block. The obtained samples were characterized from infrared and UV-vis spectroscopies, and thermogravimetric, X-ray diffraction and magnetic measurements. Anhydrous solids which crystallize with a monoclinic unit cell, in the I2/a space group with four formula units per cell (Z=4) were obtained. Their crystal structure was solved ab initio from the recorded X-ray powder patterns and then refined by the Rietveld method.more » The metal T is found with octahedral coordination to four N ends of CN groups and two imidazole molecules while the inner Ni atom preserves its planar coordination. The system of layers remains stacked in an ordered 3D structure through dipole-dipole and {pi}-{pi} interactions between imidazole rings from neighboring layers. In this way, a pillared structure is achieved without requiring the coordination of both nitrogen atoms from imidazole ring. The recorded magnetic data indicate the occurrence of a predominant ferromagnetic interaction at low temperature for Co and Ni but not for Fe. Such magnetic ordering is more favorable for Ni with transition temperature of 14.67 K, which was ascribed to the relatively high polarizing power for this metal. Within the considered T metals, to nickel the highest electron-withdrawing ability corresponds and this leads to an increase for the metal-ligand electron clouds overlapping and to a stronger {pi}-{pi} attractive interaction, two factors that result into a higher magnetic ordering temperature. - Graphical Abstract: Magnetic ordering through the {pi}-{pi} interaction between the imidazole rings. Highlights: Black-Right-Pointing-Pointer Hybrid inorganic-organic solids. Black-Right-Pointing-Pointer Hybrid inorganic-organic molecular

Coupled π π , K K ¯ scattering in P -wave and the ρ resonance from lattice QCD

DOE PAGES

Wilson, David J.; Briceño, Raúl A.; Dudek, Jozef J.; ...

2015-11-02

In this study, we determine elastic and coupled-channel amplitudes for isospin-1 meson-meson scattering inmore » $P$-wave, by calculating correlation functions using lattice QCD with light quark masses such that $$m_\\pi = 236$$ MeV in a cubic volume of $$\\sim (4 \\,\\mathrm{fm})^3$$. Variational analyses of large matrices of correlation functions computed using operator constructions resembling $$\\pi\\pi$$, $$K\\overline{K}$$ and $$q\\bar{q}$$, in several moving frames and several lattice irreducible representations, leads to discrete energy spectra from which scattering amplitudes are extracted. In the elastic $$\\pi\\pi$$ scattering region we obtain a detailed energy-dependence for the phase-shift, corresponding to a $$\\rho$$ resonance, and we extend the analysis into the coupled-channel $$K\\overline{K}$$ region for the first time, finding a small coupling between the channels.« less

Meson Form Factors and Deep Exclusive Meson Production Experiments

DOE Office of Scientific and Technical Information (OSTI.GOV)

Horn, Tanja

Pion and kaon electroproduction data play a unique role in Nature and our understanding of them is essential for explaining hadron structure. Precision longitudinaltransverse separated pion and kaon cross sections are of particular interest. They allow for the extraction of meson form factors and validation of understanding of hard exclusive and semi-inclusive reactions (π+, K+, π0, γ) towards 3D hadron imaging and potential future flavor decomposition. We review recent data and present prospects for deep exclusive pion and kaon electroproduction at the 12 GeV Jefferson Lab including the prospects to use projected charged- and neutral pion data to further determinemore » the spin, charge-parity and flavor of GPDs, including the helicity-flip GPDs.« less

Analysis of Hydra PIWI proteins and piRNAs uncover early evolutionary origins of the piRNA pathway.

PubMed

Lim, Robyn S M; Anand, Amit; Nishimiya-Fujisawa, Chiemi; Kobayashi, Satoru; Kai, Toshie

2014-02-01

To preserve genome integrity, an evolutionarily conserved small RNA-based silencing mechanism involving PIWI proteins and PIWI-interacting RNAs (piRNAs) represses potentially deleterious transposons in animals. Although there has been extensive research into PIWI proteins in bilaterians, these proteins remain to be examined in ancient phyla. Here, we investigated the PIWI proteins Hywi and Hyli in the cnidarian Hydra, and found that both PIWI proteins are enriched in multipotent stem cells, germline stem cells, and in the female germline. Hywi and Hyli localize to the nuage, a perinuclear organelle that has been implicated in piRNA-mediated transposon silencing, together with other conserved nuage and piRNA pathway components. Our findings provide the first report of nuage protein localization patterns in a non-bilaterian. Hydra PIWI proteins possess symmetrical dimethylarginines: modified residues that are known to aid in PIWI protein localization to the nuage and proper piRNA loading. piRNA profiling suggests that transposons are the major targets of the piRNA pathway in Hydra. Our data suggest that piRNA biogenesis through the ping-pong amplification cycle occurs in Hydra and that Hywi and Hyli are likely to preferentially bind primary and secondary piRNAs, respectively. Presumptive piRNA clusters are unidirectionally transcribed and primarily give rise to piRNAs that are antisense to transposons. These results indicate that various conserved features of PIWI proteins, the piRNA pathway, and their associations with the nuage were likely established before the evolution of bilaterians. Copyright © 2013 Elsevier Inc. All rights reserved.

Spallation of Cu by 500- and 1570-MeV. pi. /sup -/

DOE Office of Scientific and Technical Information (OSTI.GOV)

Haustein, P.E.; Ruth, T.J.

1978-11-01

Relative yields of 36 products extending from /sup 7/Be to /sup 65/Zn have been measured for the interaction of 500- and 1570-MeV negative pions with Cu. These results are compared with calculations from the ISOBAR model, with earlier studies of Cu spallation with lower (resonance) energy pions, energetic protons, and heavy ions. Relative yield patterns at both ..pi../sup -/ energies show only slight differences when compared to spallation by protons of comparable energy. Calculations from the ISOBAR model adequately reproduce the shapes of the mass yield and charge yield of the experimental data for 500-MeV ..pi../sup -/. The calculation, however,more » overestimates the yield of neutron-rich isotopes from deep spallation. At the 1570-MeV ..pi../sup -/ energy the yield patterns, charge-dispersion, and mass-yield curves are nearly identical to those for 2-GeV proton spallation. These results suggest that pion-nucleon resonance effects probably decrease at higher energies and that limiting fragmentation and factorization concepts may be applied to understanding high-energy pion spallation.« less

Physical principles of the amplification of electromagnetic radiation due to negative electron masses in a semiconductor superlattice

NASA Astrophysics Data System (ADS)

Shorokhov, A. V.; Pyataev, M. A.; Khvastunov, N. N.; Hyart, T.; Kusmartsev, F. V.; Alekseev, K. N.

2015-02-01

In a superlattice placed in crossed static electric and magnetic fields, under certain conditions, the inversion of electron population can appear at which the average energy of electrons is above the middle of the mini-band and the effective mass of the electron is negative. This is the implementation of the negative effective mass amplifier and generator (NEMAG) in the superlattice. It can result in the amplification and generation of terahertz radiation even in the absence of negative differential conductivity.

Measurement of branching fractions and search for CP-violating charge asymmetries in charmless two-body B decays into pions and kaons.

PubMed

Aubert, B; Boutigny, D; Gaillard, J M; Hicheur, A; Karyotakis, Y; Lees, J P; Robbe, P; Tisserand, V; Palano, A; Chen, G P; Chen, J C; Qi, N D; Rong, G; Wang, P; Zhu, Y S; Eigen, G; Reinertsen, P L; Stugu, B; Abbott, B; Abrams, G S; Borgland, A W; Breon, A B; Brown, D N; Button-Shafer, J; Cahn, R N; Clark, A R; Fan, Q; Gill, M S; Gowdy, S J; Gritsan, A; Groysman, Y; Jacobsen, R G; Kadel, R W; Kadyk, J; Kerth, L T; Kluth, S; Kolomensky, Y G; Kral, J F; LeClerc, C; Levi, M E; Liu, T; Lynch, G; Meyer, A B; Momayezi, M; Oddone, P J; Perazzo, A; Pripstein, M; Roe, N A; Romosan, A; Ronan, M T; Shelkov, V G; Telnov, A V; Wenzel, W A; Bright-Thomas, P G; Harrison, T J; Hawkes, C M; Kirk, A; Knowles, D J; O'Neale, S W; Penny, R C; Watson, A T; Watson, N K; Deppermann, T; Koch, H; Krug, J; Kunze, M; Lewandowski, B; Peters, K; Schmuecker, H; Steinke, M; Andress, J C; Barlow, N R; Bhimji, W; Chevalier, N; Clark, P J; Cottingham, W N; De Groot, N; Dyce, N; Foster, B; Mass, A; McFall, J D; Wallom, D; Wilson, F F; Abe, K; Hearty, C; Mattison, T S; McKenna, J A; Thiessen, D; Camanzi, B; Jolly, S; McKemey, A K; Tinslay, J; Blinov, V E; Bukin, A D; Bukin, D A; Buzykaev, A R; Dubrovin, M S; Golubev, V B; Ivanchenko, V N; Korol, A A; Kravchenko, E A; Onuchin, A P; Salnikov, A A; Serednyakov, S I; Skovpen, Y I; Telnov, V I; Yushkov, A N; Lankford, A J; Mandelkern, M; McMahon, S; Stoker, D P; Ahsan, A; Arisaka, K; Buchanan, C; Chun, S; Branson, J G; MacFarlane, D B; Prell, S; Rahatlou, S; Raven, G; Sharma, V; Campagnari, C; Dahmes, B; Hart, P A; Kuznetsova, N; Levy, S L; Long, O; Lu, A; Richman, J D; Verkerke, W; Witherell, M; Yellin, S; Beringer, J; Dorfan, D E; Eisner, A M; Frey, A; Grillo, A A; Grothe, M; Heusch, C A; Johnson, R P; Kroeger, W; Lockman, W S; Pulliam, T; Sadrozinski, H; Schalk, T; Schmitz, R E; Schumm, B A; Seiden, A; Turri, M; Walkowiak, W; Williams, D C; Wilson, M G; Chen, E; Dubois-Felsmann, G P; Dvoretskii, A; Hitlin, D G; Metzler, S; Oyang, J; Porter, F C; Ryd, A; Samuel, A; Weaver, M; Yang, S; Zhu, R Y; Devmal, S; Geld, T L; Jayatilleke, S; Mancinelli, G; Meadows, B T; Sokoloff, M D; Bloom, P; Fahey, S; Ford, W T; Gaede, F; Johnson, D R; Michael, A K; Nauenberg, U; Olivas, A; Park, H; Rankin, P; Roy, J; Sen, S; Smith, J G; van Hoek, W C; Wagner, D L; Blouw, J; Harton, J L; Krishnamurthy, M; Soffer, A; Toki, W H; Wilson, R J; Zhang, J; Brandt, T; Brose, J; Colberg, T; Dahlinger, G; Dickopp, M; Dubitzky, R S; Maly, E; Müller-Pfefferkorn, R; Otto, S; Schubert, K R; Schwierz, R; Spaan, B; Wilden, L; Behr, L; Bernard, D; Bonneaud, G R; Brochard, F; Cohen-Tanugi, J; Ferrag, S; Roussot, E; T'Jampens, S; Thiebaux, C; Vasileiadis, G; Verderi, M; Anjomshoaa, A; Bernet, R; Khan, A; Muheim, F; Playfer, S; Swain, J E; Falbo, M; Bozzi, C; Dittongo, S; Folegani, M; Piemontese, L; Treadwell, E; Anulli, F; Baldini-Ferroli, R; Calcaterra, A; de Sangro, R; Falciai, D; Finocchiaro, G; Patteri, P; Peruzzi, I M; Piccolo, M; Xie, Y; Zallo, A; Bagnasco, S; Buzzo, A; Contri, R; Crosetti, G; Fabbricatore, P; Farinon, S; Lo Vetere, M; Macri, M; Monge, M R; Musenich, R; Pallavicini, M; Parodi, R; Passaggio, S; Pastore, F C; Patrignani, C; Pia, M G; Priano, C; Robutti, E; Santroni, A; Morii, M; Bartoldus, R; Dignan, T; Hamilton, R; Mallik, U; Cochran, J; Crawley, H B; Fischer, P A; Lamsa, J; Meyer, W T; Rosenberg, E I; Benkebil, M; Grosdidier, G; Hast, C; Höcker, A; Lacker, H M; LePeltier, V; Lutz, A M; Plaszczynski, S; Schune, M H; Trincaz-Duvoid, S; Valassi, A; Wormser, G; Bionta, R M; Brigljevic, V; Fackler, O; Fujino, D; Lange, D J; Mugge, M; Shi, X; van Bibber, K; Wenaus, T J; Wright, D M; Wuest, C R; Carroll, M; Fry, J R; Gabathuler, E; Gamet, R; George, M; Kay, M; Payne, D J; Sloane, R J; Touramanis, C; Aspinwall, M L; Bowerman, D A; Dauncey, P D; Egede, U; Eschrich, I; Gunawardane, N J; Martin, R; Nash, J A; Sanders, P; Smith, D; Azzopardi, D E; Back, J J; Dixon, P; Harrison, P F; Potter, R J; Shorthouse, H W; Strother, P; Vidal, P B; Williams, M I; Cowan, G; George, S; Green, M G; Kurup, A; Marker, C E; McGrath, P; McMahon, T R; Ricciardi, S; Salvatore, F; Scott, I; Vaitsas, G; Brown, D; Davis, C L; Allison, J; Barlow, R J; Boyd, J T; Forti, A; Fullwood, J; Jackson, F; Lafferty, G D; Savvas, N; Simopoulos, E T; Weatherall, J H; Farbin, A; Jawahery, A; Lillard, V; Olsen, J; Roberts, D A; Schieck, J R; Blaylock, G; Dallapiccola, C; Flood, K T; Hertzbach, S S; Kofler, R; Lin, C S; Moore, T B; Staengle, H; Willocq, S; Wittlin, J; Brau, B; Cowan, R; Sciolla, G; Taylor, F; Yamamoto, R K; Britton, D I; Milek, M; Patel, P M; Trischuk, J; Lanni, F; Palombo, F; Bauer, J M; Booke, M; Cremaldi, L; Eschenburg, V; Kroeger, R; Reidy, J; Sanders, D A; Summers, D J; Martin, J P; Nief, J Y; Seitz, R; Taras, P; Zacek, V; Nicholson, H; Sutton, C S; Cartaro, C; Cavallo, N; De Nardo, G; Fabozzi, F; Gatto, C; Lista, L; Paolucci, P; Piccolo, D; Sciacca, C; LoSecco, J M; Alsmiller, J R; Gabriel, T A; Handler, T; Brau, J; Frey, R; Iwasaki, M; Sinev, N B; Strom, D; Colecchia, F; Dal Corso, F; Dorigo, A; Galeazzi, F; Margoni, M; Michelon, G; Morandin, M; Posocco, M; Rotondo, M; Simonetto, F; Stroili, R; Torassa, E; Voci, C; Benayoun, M; Briand, H; Chauveau, J; David, P; De La Vaissière, C; Del Buono, L; Hamon, O; Le Diberder, F; Leruste, P; Lory, J; Roos, L; Stark, J; Versillé, S; Manfredi, P F; Re, V; Speziali, V; Frank, E D; Gladney, L; Guo, Q H; Panetta, J H; Angelini, C; Batignani, G; Bettarini, S; Bondioli, M; Carpinelli, M; Forti, F; Giorgi, M A; Lusiani, A; Martinez-Vidal, F; Morganti, M; Neri, N; Paoloni, E; Rama, M; Rizzo, G; Sandrelli, F; Simi, G; Triggiani, G; Walsh, J; Haire, M; Judd, D; Paick, K; Turnbull, L; Wagoner, D E; Albert, J; Bula, C; Lu, C; McDonald, K T; Miftakov, V; Schaffner, S F; Smith, A J; Tumanov, A; Varnes, E W; Cavoto, G; del Re, D; Faccini, R; Ferrarotto, F; Ferroni, F; Fratini, K; Lamanna, E; Leonardi, E; Mazzoni, M A; Morganti, S; Pierini, M; Piredda, G; Safai Tehrani, F; Serra, M; Voena, C; Christ, S; Waldi, R; Adye, T; Franek, B; Geddes, N I; Gopal, G P; Xella, S M; Aleksan, R; De Domenico, G; Emery, S; Gaidot, A; Ganzhur, S F; Giraud, P F; Hamel De Monchenault, G; Kozanecki, W; Langer, M; London, G W; Mayer, B; Serfass, B; Vasseur, G; Yeche, C; Zito, M; Copty, N; Purohit, M V; Singh, H; Yumiceva, F X; Adam, I; Anthony, P L; Aston, D; Baird, K; Bartelt, J; Bloom, E; Boyarski, A M; Bulos, F; Calderini, G; Claus, R; Convery, M R; Coupal, D P; Coward, D H; Dorfan, J; Doser, M; Dunwoodie, W; Field, R C; Glanzman, T; Godfrey, G L; Grosso, P; Himel, T; Huffer, M E; Innes, W R; Jessop, C P; Kelsey, M H; Kim, P; Kocian, M L; Langenegger, U; Leith, D W; Luitz, S; Luth, V; Lynch, H L; Manzin, G; Marsiske, H; Menke, S; Messner, R; Moffeit, K C; Mount, R; Muller, D R; O'Grady, C P; Petrak, S; Quinn, H; Ratcliff, B N; Robertson, S H; Rochester, L S; Roodman, A; Schietinger, T; Schindler, R H; Schwiening, J; Serbo, V V; Snyder, A; Soha, A; Spanier, S M; Stahl, A; Stelzer, J; Su, D; Sullivan, M K; Talby, M; Tanaka, H A; Trunov, A; Va'vra, J; Wagner, S R; Weinstein, A J; Wisniewski, W J; Young, C C; Burchat, P R; Cheng, C H; Kirkby, D; Meyer, T I; Roat, C; De Silva, A; Henderson, R; Bugg, W; Cohn, H; Hart, E; Weidemann, A W; Benninger, T; Izen, J M; Kitayama, I; Lou, X C; Turcotte, M; Bianchi, F; Bona, M; Di Girolamo, B; Gamba, D; Smol, A; Zanin, D; Bosisio, L; Della Ricca, G; Lanceri, L; Pompili, A; Poropat, P; Prest, M; Vallazza, E; Vuagnin, G; Panvini, R S; Brown, C M; Kowalewski, R; Roney, J M; Band, H R; Charles, E; Dasu, S; Elmer, P; Hu, H; Johnson, J R; Liu, R; Nielsen, J; Orejudos, W; Pan, Y; Prepost, R; Scott, I J; Sekula, S J; von Wimmersperg-Toeller, J H; Wu, S L; Yu, Z; Zobering, H; Kordich, T M; Neal, H

2001-10-08

We present measurements, based on a sample of approximately 23x10(6) BB pairs, of the branching fractions and a search for CP-violating charge asymmetries in charmless hadronic decays of B mesons into two-body final states of kaons and pions. We find the branching fractions B(B0-->pi(+)pi(-)) = (4.1+/-1.0+/-0.7)x10(-6), B(B0-->K+pi(-)) = (16.7+/-1.6+/-1.3)x10(-6), B(B+-->K+pi(0)) = (10.8(+2.1)(-1.9)+/-1.0)x10(-6), B(B+-->K0pi(+)) = (18.2(+3.3)(-3.0)+/-2.0)x10(-6), B(B0-->K0pi(0)) = (8.2(+3.1)(-2.7)+/-1.2)x10(-6). We also report 90% confidence level upper limits for B meson decays to the pi(+)pi(0), K+K-, and K0K+ final states. In addition, charge asymmetries have been found to be consistent with zero, where the statistical precision is in the range of +/-0.10 to +/-0.18, depending on the decay mode.

Time Evolution of Meson Density During Formation of Expanding Quark-Antiquark System

NASA Astrophysics Data System (ADS)

Ghaffary, Tooraj

2018-04-01

Recently some researchers (Sepehri and Shoorvazi Astrophys. Spaces Sci. 344(2), 521-527, 2013) have considered the Universe as an acceleration cylindrical system. Motivated by their work and using their method in QCD, this paper has been cleared that because the acceleration of expansion in quark-antiquark system is relatively very large, one horizon is appeared outside the system. To obtain the total cross section of meson near this horizon, we need to multiply the production cross section for appeared horizon by the density of meson produced outside the system. As it can be seen by an observer who is outside the meson formation process, this cross section depends on time so the event horizon is now a time depended process.

Comparison of characteristics of {Delta}{sup 0}(1232) produced in p{sup 12}C and d{sup 12}C collisions at 4.2 A GeV/c

DOE Office of Scientific and Technical Information (OSTI.GOV)

Olimov, Kh. K., E-mail: olimov@comsats.edu.pk; Haseeb, Mahnaz Q., E-mail: mahnazhaseeb@comsats.edu.pk; Khan, Imran

2012-04-15

Reconstructed momentum, transverse momentum, kinetic energy, rapidity, and emission angle distributions along with their mean values were compared for {Delta}{sup 0}(1232) resonances produced in p{sup 12}C and d{sup 12}C collisions at 4.2 A GeV/c. Mean momentum, transverse momentum, and rapidity of protons and negative pions coming from {Delta}{sup 0}(1232) decay were extracted and compared with the corresponding mean values for protons and {pi}{sup -} mesons in experiment and the relevant model calculations.

Rare B Meson Decays With Omega Mesons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Zhang, Lei; /Colorado U.

2006-04-24

Rare charmless hadronic B decays are particularly interesting because of their importance in understanding the CP violation, which is essential to explain the matter-antimatter asymmetry in our universe, and of their roles in testing the ''effective'' theory of B physics. The study has been done with the BABAR experiment, which is mainly designed for the study of CP violation in the decays of neutral B mesons, and secondarily for rare processes that become accessible with the high luminosity of the PEP-II B Factory. In a sample of 89 million produced B{bar B} pairs on the BABAR experiment, we observed themore » decays B{sup 0} {yields} {omega}K{sup 0} and B{sup +} {yields} {omega}{rho}{sup +} for the first time, made more precise measurements for B{sup +} {yields} {omega}h{sup +} and reported tighter upper limits for B {yields} {omega}K* and B{sup 0} {yields} {omega}{rho}{sup 0}.« less

Measurement of the transition form factor of {eta} meson with WASA-at-COSY

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bhatt, H.

2011-10-24

Reaction {eta}{yields}e{sup +}e{sup -}{gamma} is used to investigate the transition form factor of {eta} meson with WASA detector at COSY. Where the {eta} meson is produced in pp collision at 1.4 GeV. We present the analysis techniques and preliminary results of {eta} Dalitz decays.

Probing the P -wave charmonium decays of Bc meson

NASA Astrophysics Data System (ADS)

Rui, Zhou

2018-02-01

Motivated by the large number of Bc meson decay modes observed recently by several detectors at the LHC, we present a detailed analysis of the Bc meson decaying to the P -wave charmonium states and a light pseudoscalar (P ) or vector (V ) meson within the framework of perturbative QCD factorization. The P -wave charmonium distribution amplitudes are extracted from the n =2 , l =1 Schrödinger states for a Coulomb potential, which can be taken as the universal nonperturbative objects to analyze the hard exclusive processes with P -wave charmonium production. It is found that these decays have large branching ratios of the order of 10-5˜10-2 , which seem to be in the reach of future experiments. We also provide predictions for the polarization fractions and relative phases of Bc→(χc 1,χc 2,hc)V decays. It is expected that the longitudinal polarization amplitudes dominate the branching ratios according to the quark helicity analysis, and the magnitudes and phases of parallel polarization amplitude are approximately equal to the perpendicular ones. The obtained results are compared with available experimental data, our previous studies, and numbers from other approaches.

A postsynaptic PI3K-cII dependent signaling controller for presynaptic homeostatic plasticity

PubMed Central

Hauswirth, Anna G; Ford, Kevin J; Wang, Tingting; Fetter, Richard D; Tong, Amy

2018-01-01

Presynaptic homeostatic plasticity stabilizes information transfer at synaptic connections in organisms ranging from insect to human. By analogy with principles of engineering and control theory, the molecular implementation of PHP is thought to require postsynaptic signaling modules that encode homeostatic sensors, a set point, and a controller that regulates transsynaptic negative feedback. The molecular basis for these postsynaptic, homeostatic signaling elements remains unknown. Here, an electrophysiology-based screen of the Drosophila kinome and phosphatome defines a postsynaptic signaling platform that includes a required function for PI3K-cII, PI3K-cIII and the small GTPase Rab11 during the rapid and sustained expression of PHP. We present evidence that PI3K-cII localizes to Golgi-derived, clathrin-positive vesicles and is necessary to generate an endosomal pool of PI(3)P that recruits Rab11 to recycling endosomal membranes. A morphologically distinct subdivision of this platform concentrates postsynaptically where we propose it functions as a homeostatic controller for retrograde, trans-synaptic signaling. PMID:29303480

Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis

PubMed Central

Button, Robert W.; Vincent, Joseph H.; Strang, Conor J.; Luo, Shouqing

2016-01-01

The PI-3 kinase (PI-3K)/mTOR pathway is critical for cell growth and proliferation. Strategies of antagonising this signaling have proven to be detrimental to cell survival. This observation, coupled with the fact many tumours show enhanced growth signaling, has caused dual inhibitors of PI-3K and mTOR to be implicated in cancer treatment, and have thus been studied across various tumour models. Since PI-3K (class-I)/mTOR pathway negatively regulates autophagy, dual inhibitors of PI-3K/mTOR are currently believed to be autophagy activators. However, our present data show that the dual PI-3K/mTOR inhibition (DKI) potently suppresses autophagic flux. We further confirm that inhibition of Vps34/PI3KC3, the class-III PI-3K, causes the blockade to autophagosome-lysosome fusion. Our data suggest that DKI induces cell death independently of apoptosis and necroptosis, whereas autophagy perturbation by DKI may contribute to cell death. Given that autophagy is critical in cellular homeostasis, our study not only clarifies the role of a dual PI-3K/mTOR inhibitor in autophagy, but also suggests that its autophagy inhibition needs to be considered if such an agent is used in cancer chemotherapy. PMID:26814436

Fluctuations in the quark-meson model for QCD with isospin chemical potential

NASA Astrophysics Data System (ADS)

Kamikado, Kazuhiko; Strodthoff, Nils; von Smekal, Lorenz; Wambach, Jochen

2013-01-01

We study the two-flavor quark-meson (QM) model with the functional renormalization group (FRG) to describe the effects of collective mesonic fluctuations on the phase diagram of QCD at finite baryon and isospin chemical potentials, μB and μI. With only isospin chemical potential there is a precise equivalence between the competing dynamics of chiral versus pion condensation and that of collective mesonic and baryonic fluctuations in the quark-meson-diquark model for two-color QCD at finite baryon chemical potential. Here, finite μB = 3 μ introduces an additional dimension to the phase diagram as compared to two-color QCD, however. At zero temperature, the (μI, μ) plane of this phase diagram is strongly constrained by the "Silver Blaze problem." In particular, the onset of pion condensation must occur at μI =mπ / 2, independent of μ as long as μ +μI stays below the constituent quark mass of the QM model or the liquid-gas transition line of nuclear matter in QCD. In order to maintain this relation beyond mean field it is crucial to compute the pion mass from its timelike correlator with the FRG in a consistent way.

Cellular and in vivo activity of a novel PI3K inhibitor, PX-866, against human glioblastoma

PubMed Central

Koul, Dimpy; Shen, Ruijun; Kim, Yong-Wan; Kondo, Yasuko; Lu, Yiling; Bankson, Jim; Ronen, Sabrina M.; Kirkpatrick, D. Lynn; Powis, Garth; Yung, W. K. Alfred

2010-01-01

The phosphatidylinositol-3-kinase (PI3K)/Akt oncogenic pathway is critical in glioblastomas. Loss of PTEN, a negative regulator of the PI3K pathway or activated PI3K/Akt pathway that drive increased proliferation, survival, neovascularization, glycolysis, and invasion is found in 70%–80% of malignant gliomas. Thus, PI3K is an attractive therapeutic target for malignant glioma. We report that a new irreversible PI3K inhibitor, PX-866, shows potent inhibitory effects on the PI3K/Akt signaling pathway in glioblastoma. PX-866 did not induce any apoptosis in glioma cells; however, an increase in autophagy was observed. PX-866 inhibited the invasive and angiogenic capabilities of cultured glioblastoma cells. In vivo, PX-866 inhibited subcutaneous tumor growth and increased the median survival time of animals with intracranial tumors. We also assessed the potential of proton magnetic resonance spectroscopy (MRS) as a noninvasive method to monitor response to PX-866. Our findings show that PX-866 treatment causes a drop in the MRS-detectable choline-to-NAA, ratio and identify this partial normalization of the tumor metabolic profile as a biomarker of molecular drug action. Our studies affirm that the PI3K pathway is a highly specific molecular target for therapies for glioblastoma and other cancers with aberrant PI3K/PTEN expression. PMID:20156803

Amplitude Analysis of the Decay $$D_s^+ \\to \\pi^+ \\pi^- \\pi^+$$ in the Experiment E831/FOCUS (in Portuguese)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schilithz, Anderson Correa; /Rio de Janeiro, CBPF

We present in this thesis the Dalitz Plot analysis of the D{sub s}{sup +} {yields} {pi}{sup +}{pi}{sup -}{pi}{sup +} decay, with the data of the E831/FOCUS, that took data in 1996 and 1997. The masses and widhts of f{sub 0}(980) and f{sub 0}(1370) are free parametres of the fit on Dalitz Plot, objectiving to study in detail these resonances. After this analysis we present the Spectator Model study on the S wave in this decay. For this study we used the formalism developed by M. Svec [2] for scattering. We present the comparison between the Isobar Model, frequently used inmore » Dalitz Plot analysis, and this formalism.« less

Proactive and Retroactive Effects of Negative Suggestion

ERIC Educational Resources Information Center

Brown, Alan S.; Brown, Christine M.; Mosbacher, Joy L.; Dryden, W. Erich

2006-01-01

The negative effects of false information presented either prior to (proactive interference; PI) or following (retroactive interference; RI) true information was examined with word definitions (Experiment 1) and trivia facts (Experiment 2). Participants were explicitly aware of which information was true and false when shown, and true-false…

Defining Genomic Changes in Triple-Negative Breast Cancer in Women of African Descent

DTIC Science & Technology

2012-06-01

Triple negative breast cancer • Ethnic disparities • Breast cancer amongst African Americans and Africans • Gene expression profiling • Array... negative cases seen in both African and African - American breast cancer cases. Gene Expression Array Studies The 31 triple negative Kijabe... African - American Adjacent Normal Breast Tissue PI: Pegram &

Defining Genomic Changes in Triple-Negative Breast Cancer in Women of African Descent

DTIC Science & Technology

2012-06-01

African and African - American breast cancer cases. Gene Expression Array Studies The 31 triple negative Kijabe samples were... American Adjacent Normal Breast Tissue PI: Pegram & Baumbach Defining Genomic Changes in Triple Negative Breast Cancer in Women of African ...Tissues from African - American and East African Patients with Triple Negative Breast

Partonic Flow and phi-Meson production in Au+Au collisions at sqrt radical sNN = 200 GeV.

PubMed

Abelev, B I; Aggarwal, M M; Ahammed, Z; Anderson, B D; Arkhipkin, D; Averichev, G S; Bai, Y; Balewski, J; Barannikova, O; Barnby, L S; Baudot, J; Baumgart, S; Belaga, V V; Bellingeri-Laurikainen, A; Bellwied, R; Benedosso, F; Betts, R R; Bhardwaj, S; Bhasin, A; Bhati, A K; Bichsel, H; Bielcik, J; Bielcikova, J; Bland, L C; Blyth, S-L; Bombara, M; Bonner, B E; Botje, M; Bouchet, J; Brandin, A V; Bravar, A; Burton, T P; Bystersky, M; Cadman, R V; Cai, X Z; Caines, H; Calderón de la Barca Sánchez, M; Callner, J; Catu, O; Cebra, D; Chajecki, Z; Chaloupka, P; Chattopadhyay, S; Chen, H F; Chen, J H; Chen, J Y; Cheng, J; Cherney, M; Chikanian, A; Christie, W; Chung, S U; Coffin, J P; Cormier, T M; Cosentino, M R; Cramer, J G; Crawford, H J; Das, D; Dash, S; Daugherity, M; de Moura, M M; Dedovich, T G; DePhillips, M; Derevschikov, A A; Didenko, L; Dietel, T; Djawotho, P; Dogra, S M; Dong, X; Drachenberg, J L; Draper, J E; Du, F; Dunin, V B; Dunlop, J C; Dutta Mazumdar, M R; Eckardt, V; Edwards, W R; Efimov, L G; Emelianov, V; Engelage, J; Eppley, G; Erazmus, B; Estienne, M; Fachini, P; Fatemi, R; Fedorisin, J; Feng, A; Filip, P; Finch, E; Fine, V; Fisyak, Y; Fu, J; Gagliardi, C A; Gaillard, L; Ganti, M S; Garcia-Solis, E; Ghazikhanian, V; Ghosh, P; Gorbunov, Y G; Gos, H; Grebenyuk, O; Grosnick, D; Grube, B; Guertin, S M; Guimaraes, K S F F; Gupta, N; Haag, B; Hallman, T J; Hamed, A; Harris, J W; He, W; Heinz, M; Henry, T W; Heppelmann, S; Hippolyte, B; Hirsch, A; Hjort, E; Hoffman, A M; Hoffmann, G W; Hofman, D J; Hollis, R S; Horner, M J; Huang, H Z; Hughes, E W; Humanic, T J; Igo, G; Iordanova, A; Jacobs, P; Jacobs, W W; Jakl, P; Jia, F; Jones, P G; Judd, E G; Kabana, S; Kang, K; Kapitan, J; Kaplan, M; Keane, D; Kechechyan, A; Kettler, D; Khodyrev, V Yu; Kim, B C; Kiryluk, J; Kisiel, A; Kislov, E M; Klein, S R; Knospe, A G; Kocoloski, A; Koetke, D D; Kollegger, T; Kopytine, M; Kotchenda, L; Kouchpil, V; Kowalik, K L; Kravtsov, P; Kravtsov, V I; Krueger, K; Kuhn, C; Kulikov, A I; Kumar, A; Kurnadi, P; Kuznetsov, A A; Lamont, M A C; Landgraf, J M; Lange, S; LaPointe, S; Laue, F; Lauret, J; Lebedev, A; Lednicky, R; Lee, C-H; Lehocka, S; LeVine, M J; Li, C; Li, Q; Li, Y; Lin, G; Lin, X; Lindenbaum, S J; Lisa, M A; Liu, F; Liu, H; Liu, J; Liu, L; Ljubicic, T; Llope, W J; Longacre, R S; Love, W A; Lu, Y; Ludlam, T; Lynn, D; Ma, G L; Ma, J G; Ma, Y G; Mahapatra, D P; Majka, R; Mangotra, L K; Manweiler, R; Margetis, S; Markert, C; Martin, L; Matis, H S; Matulenko, Yu A; McClain, C J; McShane, T S; Melnick, Yu; Meschanin, A; Millane, J; Miller, M L; Minaev, N G; Mioduszewski, S; Mironov, C; Mischke, A; Mitchell, J; Mohanty, B; Morozov, D A; Munhoz, M G; Nandi, B K; Nattrass, C; Nayak, T K; Nelson, J M; Nepali, C; Netrakanti, P K; Nogach, L V; Nurushev, S B; Odyniec, G; Ogawa, A; Okorokov, V; Oldenburg, M; Olson, D; Pachr, M; Pal, S K; Panebratsev, Y; Pavlinov, A I; Pawlak, T; Peitzmann, T; Perevoztchikov, V; Perkins, C; Peryt, W; Phatak, S C; Planinic, M; Pluta, J; Poljak, N; Porile, N; Poskanzer, A M; Potekhin, M; Potrebenikova, E; Potukuchi, B V K S; Prindle, D; Pruneau, C; Putschke, J; Qattan, I A; Raniwala, R; Raniwala, S; Ray, R L; Relyea, D; Ridiger, A; Ritter, H G; Roberts, J B; Rogachevskiy, O V; Romero, J L; Rose, A; Roy, C; Ruan, L; Russcher, M J; Sahoo, R; Sakrejda, I; Sakuma, T; Salur, S; Sandweiss, J; Sarsour, M; Sazhin, P S; Schambach, J; Scharenberg, R P; Schmitz, N; Seger, J; Selyuzhenkov, I; Seyboth, P; Shabetai, A; Shahaliev, E; Shao, M; Sharma, M; Shen, W Q; Shimanskiy, S S; Sichtermann, E P; Simon, F; Singaraju, R N; Smirnov, N; Snellings, R; Sorensen, P; Sowinski, J; Speltz, J; Spinka, H M; Srivastava, B; Stadnik, A; Stanislaus, T D S; Staszak, D; Stock, R; Strikhanov, M; Stringfellow, B; Suaide, A A P; Suarez, M C; Subba, N L; Sumbera, M; Sun, X M; Sun, Z; Surrow, B; Symons, T J M; Szanto de Toledo, A; Takahashi, J; Tang, A H; Tarnowsky, T; Thomas, J H; Timmins, A R; Timoshenko, S; Tokarev, M; Trainor, T A; Trentalange, S; Tribble, R E; Tsai, O D; Ulery, J; Ullrich, T; Underwood, D G; Van Buren, G; van der Kolk, N; van Leeuwen, M; Vander Molen, A M; Varma, R; Vasilevski, I M; Vasiliev, A N; Vernet, R; Vigdor, S E; Viyogi, Y P; Vokal, S; Voloshin, S A; Waggoner, W T; Wang, F; Wang, G; Wang, J S; Wang, X L; Wang, Y; Watson, J W; Webb, J C; Westfall, G D; Wetzler, A; Whitten, C; Wieman, H; Wissink, S W; Witt, R; Wu, J; Wu, Y; Xu, N; Xu, Q H; Xu, Z; Yepes, P; Yoo, I-K; Yue, Q; Yurevich, V I; Zhan, W; Zhang, H; Zhang, W M; Zhang, Y; Zhang, Z P; Zhao, Y; Zhong, C; Zhou, J; Zoulkarneev, R; Zoulkarneeva, Y; Zubarev, A N; Zuo, J X

2007-09-14

We present first measurements of the phi-meson elliptic flow (v2(pT)) and high-statistics pT distributions for different centralities from radical sNN=200 GeV Au+Au collisions at RHIC. In minimum bias collisions the v2 of the phi meson is consistent with the trend observed for mesons. The ratio of the yields of the Omega to those of the phi as a function of transverse momentum is consistent with a model based on the recombination of thermal s quarks up to pT approximately 4 GeV/c, but disagrees at higher momenta. The nuclear modification factor (R CP) of phi follows the trend observed in the K S 0 mesons rather than in Lambda baryons, supporting baryon-meson scaling. These data are consistent with phi mesons in central Au+Au collisions being created via coalescence of thermalized s quarks and the formation of a hot and dense matter with partonic collectivity at RHIC.

Functional Interactions between Major Rice Blast Resistance Genes, Pi-ta and Pi-b, and Minor Blast Resistance QTL.

PubMed

Chen, Xinglong; Jia, Yulin; Jia, Melissa H; Pinson, Shannon; Wang, Xueyan; Wu, Bo Ming

2018-04-16

Major blast resistance (R) genes confer resistance in a gene-for-gene manner. However, little information is available on interactions between R genes. In this study, interactions between two rice blast R genes, Pi-ta and Pi-b, and other minor blast resistance quantitative trait loci (QTL) were investigated in a recombinant inbred line (RIL) population comprising of 243 RILs from a 'Cybonnet' (CYBT)×'Saber' (SB) cross. CYBT has the R gene Pi-ta and SB has Pi-b. Ten differential isolates of four Magnaporthe oryzae races (IB-1, IB-17, IB-49, and IE-1K) were used to evaluate disease reactions of the 243 RILs under greenhouse conditions. Five resistance QTL were mapped on chromosomes 2, 3, 8, 9, and 12 with a linkage map of 179 single nucleotide polymorphism (SNP) markers. Among them, qBR12 (Q1), was mapped at the Pi-ta locus and accounted for 45.41% of phenotypic variation while qBR2 (Q2) was located at the Pi-b locus and accounted for24.81%of disease reactions. An additive-by-additive epistatic interaction between Q1 (Pi-ta) and Q2 (Pi-b) was detected; they can enhance the disease resistance by an additive 0.93 using the 0 to 9 standard phenotyping method. These results suggest that Pi-ta interacts synergistically with Pi-b.

Single meson production in photon-photon collisions and infrared renormalons

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ahmadov, A. I.; Department of Theoretical Physics, Baku State University, Z. Khalilov Street 23, AZ-1148, Baku; Aydin, Coskun

2010-03-01

In this article, we investigate the contribution of the higher-twist Feynman diagrams to the large-p{sub T} inclusive single meson production cross section in photon-photon collisions and present the general formulas for the higher-twist differential cross sections in case of the running coupling and frozen coupling approaches. The structure of infrared renormalon singularities of the higher-twist subprocess cross section and the resummed expression (the Borel sum) for it are found. We compared the resummed higher-twist cross sections with the ones obtained in the framework of the frozen coupling approach and leading-twist cross section. We obtain, that ratio R=({Sigma}{sub M}{sup +HT}){sup res}/({Sigma}{submore » M}{sup +HT}){sup 0}, for all values of the transverse momentum p{sub T} of the meson identically equivalent to ratio r=({Delta}{sub M}{sup HT}){sup res}/({Delta}{sub M}{sup HT}){sup 0}. It is shown that the resummed result depends on the choice of the meson wave functions used in calculation. Phenomenological effects of the obtained results are discussed.« less

Regarding the Charmed-Strange Member of the 23 S 1 Meson State

PubMed Central

Feng, Xue-Chao; Chen, Jing

2013-01-01

By employing the mass relations derived from the mass matrix and Regge trajectory, we investigate the masses of charmed and charmed-strange members of the 23 S 1 meson. The masses are compared with the values predicted by other theoretical approaches and experimental data. The results may be useful for the discovery of the unobserved meson and the determination of the quantum number of the newly discovered states. PMID:24250272

Exclusive Backward-Angle Omega Meson Electroproduction

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wenliang, Li

Exclusive meson electroproduction at different squared four-momenta of the exchanged virtual photon, Q 2 , and at different four-momentum transfers, t and u, can be used to probe QCD's transition from hadronic degrees of freedom at the long distance scale to quark-gluon degrees of freedom at the short distance scale. Backward-angle meson electroproduction was previously ignored, but is anticipated to offer complimentary information to conventional forward-angle meson electroproduction studies on nucleon structure. This work is a pioneering study of backward-angle ω cross sections through the exclusive 1H(e, e'p)ω reaction using the missing mass reconstruction technique. The extracted cross sections aremore » separated into the transverse (T), longitudinal (L), and LT, TT interference terms. The analyzed data were part of experiment E01-004 (Fπ-2), which used 2.6-5.2 GeV electron beams and HMS+SOS spectrometers in Jefferson Lab Hall C. The primary objective was to detect coincidence π in the forward-angle, where the backward-angle omega events were fortuitously detected. The experiment has central Q 2 values of 1.60 and 2.45 GeV 2 , at W = 2.21 GeV. There was significant coverage in phi and epsilon, which allowed separation of σ T,L,LT,TT . The data set has a unique u coverage of -u ~ 0, which corresponds to -t > 4 GeV 2 . The separated σ T result suggest a flat ~ 1/Q 1.33±1.21 dependence, whereas sigma_L seems to hold a stronger 1/Q 9.43±6.28 dependence. The σL/σ T ratio indicate σ T dominance at Q 2 = 2.45 GeV 2 at the ~90% confidence level. After translating the results into the -t space of the published CLAS data, our data show evidence of a backward-angle omega electroproduction peak at both Q 2 settings. Previously, this phenomenon showing both forward and backward-angle peaks was only observed in the meson photoproduction data. Through comparison of our σ T data with the prediction of the Transition Distribution Amplitude (TDA) model, and signs

Meson effective mass in the isospin medium in hard-wall AdS/QCD model

NASA Astrophysics Data System (ADS)

Mamedov, Shahin

2016-02-01

We study a mass splitting of the light vector, axial-vector, and pseudoscalar mesons in the isospin medium in the framework of the hard-wall model. We write an effective mass definition for the interacting gauge fields and scalar field introduced in gauge field theory in the bulk of AdS space-time. Relying on holographic duality we obtain a formula for the effective mass of a boundary meson in terms of derivative operator over the extra bulk coordinate. The effective mass found in this way coincides with the one obtained from finding of poles of the two-point correlation function. In order to avoid introducing distinguished infrared boundaries in the quantization formula for the different mesons from the same isotriplet we introduce extra action terms at this boundary, which reduces distinguished values of this boundary to the same value. Profile function solutions and effective mass expressions were found for the in-medium ρ , a_1, and π mesons.

Pion polarizabilities from a γ γ → π π analysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dai, Ling -Yun; Pennington, Michael R.

Here, we present results for pion polarizabilities predicted using dispersion relations from our earlier Amplitude Analysis of world data on two photon production of meson pairs. The helicity-zero polarizabilities are rather stable and insensitive to uncertainties in cross-channel exchanges. The need is first to confirm the recent result onmore » $$(\\alpha_1-\\beta_1)$$ for the charged pion by COMPASS at CERN to an accuracy of 10% by measuring the $$\\gamma\\gamma\\to\\pi^+\\pi^-$$ cross-section to an uncertainty of ~1\\%. Then the same polarizability, but for the $$\\pi^0$$, is fixed to be $$(\\alpha_1-\\beta_1)_{\\pi^0}=(0.9\\pm0.2)\\times 10^{-4}$$ fm$$^{3}$$. By analyzing the correlation between uncertainties in the meson polarizability and those in $$\\gamma\\gamma$$ cross-sections, we suggest experiments need to measure these cross-sections between $$\\sqrt{s}\\simeq 350$$ and 600~MeV. The $$\\pi^0\\pi^0$$ cross-section then makes the $$(\\alpha_2-\\beta_2)_{\\pi^0}$$ the easiest helicity-two polarizability to determine.« less

Pion polarizabilities from a γ γ → π π analysis

DOE PAGES

Dai, Ling -Yun; Pennington, Michael R.

2016-12-30

Here, we present results for pion polarizabilities predicted using dispersion relations from our earlier Amplitude Analysis of world data on two photon production of meson pairs. The helicity-zero polarizabilities are rather stable and insensitive to uncertainties in cross-channel exchanges. The need is first to confirm the recent result onmore » $$(\\alpha_1-\\beta_1)$$ for the charged pion by COMPASS at CERN to an accuracy of 10% by measuring the $$\\gamma\\gamma\\to\\pi^+\\pi^-$$ cross-section to an uncertainty of ~1\\%. Then the same polarizability, but for the $$\\pi^0$$, is fixed to be $$(\\alpha_1-\\beta_1)_{\\pi^0}=(0.9\\pm0.2)\\times 10^{-4}$$ fm$$^{3}$$. By analyzing the correlation between uncertainties in the meson polarizability and those in $$\\gamma\\gamma$$ cross-sections, we suggest experiments need to measure these cross-sections between $$\\sqrt{s}\\simeq 350$$ and 600~MeV. The $$\\pi^0\\pi^0$$ cross-section then makes the $$(\\alpha_2-\\beta_2)_{\\pi^0}$$ the easiest helicity-two polarizability to determine.« less

Dual PI3K/mTOR inhibitors, GSK2126458 and PKI-587, suppress tumor progression and increase radiosensitivity in nasopharyngeal carcinoma.

PubMed

Liu, Tongxin; Sun, Quanquan; Li, Qi; Yang, Hua; Zhang, Yuqin; Wang, Rong; Lin, Xiaoshan; Xiao, Dong; Yuan, Yawei; Chen, Longhua; Wang, Wei

2015-02-01

Although combined chemoradiotherapy has provided considerable improvements for nasopharyngeal carcinoma (NPC), recurrence and metastasis are still frequent. The PI3K/Akt/mTOR pathway plays a critical role in tumor formation and tumor cell survival after radiation-induced DNA damage. In the present study, we evaluated whether inhibition of PI3K/mTOR by two novel dual inhibitors, GSK2126458 and PKI-587, could suppress tumor progression and sensitize NPC cells to radiation. Four NPC cell lines (CNE-1, CNE-2, 5-8F, and 6-10B) were used to analyze the effects of GSK216458 and PKI-587 on cell proliferation, migration, invasion, clonogenic survival, amount of residual γ-H2AX foci, cell cycle, and apoptosis after radiation. A 5-8F xenograft model was used to evaluate the in vivo effects of the two compounds in combination with ionizing radiation (IR). Both GSK216458 and PKI-587 effectively inhibited cell proliferation and motility in NPC cells and suppressed phosphorylation of Akt, mTOR, S6, and 4EBP1 proteins in a concentration- and time-dependent manner. Moreover, both compounds sensitized NPC cells to IR by increasing DNA damage, enhancing G2-M cell-cycle delay, and inducing apoptosis. In vivo, the combination of IR with GSK2126458 or PKI-587 significantly inhibited tumor growth. Antitumor effect was correlated with induction of apoptosis and suppression of the phosphorylation of mTOR, Akt, and 4EBP1. These new findings suggest the usefulness of PI3K/mTOR dual inhibition for antitumor and radiosensitizing. The combination of IR with a dual PI3K/mTOR inhibitor, GSK2126458 or PKI-587, might be a promising therapeutic strategy for NPC. ©2014 American Association for Cancer Research.

MiR-141-3p is upregulated in esophageal squamous cell carcinoma and targets pleckstrin homology domain leucine-rich repeat protein phosphatase-2, a negative regulator of the PI3K/AKT pathway.

PubMed

Ishibashi, Osamu; Akagi, Ichiro; Ogawa, Yota; Inui, Takashi

2018-05-11

The phosphatidylinositol-3-kinase (PI3K)/AKT pathway is frequently activated in various human cancers and plays essential roles in their development and progression. Accumulating evidence suggests that dysregulated expression of microRNAs (miRNAs) is closely associated with cancer progression and metastasis. Here, we focused on miRNAs that could regulate genes related to the PI3K/AKT pathway in esophageal squamous cell carcinoma (ESCC). To identify upregulated miRNAs and their possible target genes in ESCC, we performed microarray-based integrative analyses of miRNA and mRNA expression levels in three human ESCC cell lines and a normal esophageal epithelial cell line. The miRNA microarray analysis revealed that miR-31-5p, miR-141-3p, miR-200b-3p, miR-200c-3p, and miR-205-5p were expressed at higher levels in the ESCC cell lines than the normal esophageal epithelial cell line. Bioinformatical analyses of mRNA microarray data identified several AKT/PI3K pathway-related genes as candidate targets of these miRNAs, which include tumor suppressors such as DNA-damage-inducible transcript 4 and pleckstrin homology domain leucine-rich repeat protein phosphatase-2 (PHLPP2). To validate the targets of relevant miRNAs experimentally, synthetic mimics of the miRNAs were transfected into the esophageal epithelial cell line. Here, we report that miR-141-3p suppress the expression of PHLPP2, a negative regulators of the AKT/PI3K pathway, as a target in ESCC. Copyright © 2018 Elsevier Inc. All rights reserved.

D meson production asymmetry, unfavored fragmentation, and consequences for prompt atmospheric neutrino production

NASA Astrophysics Data System (ADS)

Maciuła, Rafał; Szczurek, Antoni

2018-04-01

We consider unfavored light quark/antiquark to D meson fragmentation. We discuss nonperturbative effects for small transverse momenta. The asymmetry for D+ and D- production measured by the LHCb collaboration provides natural constraints on the parton (quark/antiquark) fragmentation functions. We find that already a fraction of q /q ¯→D fragmentation probability is sufficient to account for the measured asymmetry. We make predictions for similar asymmetry for neutral D mesons. Large D -meson production asymmetries are found for large xF which is related to dominance of light quark/antiquark q /q ¯→D fragmentation over the standard c →D fragmentation. As a consequence, prompt atmospheric neutrino flux at high neutrino energies can be much larger than for the conventional c →D fragmentation. The latter can constitute a sizeable background for the cosmic neutrinos claimed to be observed recently by the IceCube Observatory. Large rapidity-dependent D+/D- and D0/D¯0 asymmetries are predicted for low (√{s }=20 - 100 GeV ) energies. The q /q ¯→D fragmentation leads to enhanced production of D mesons at low energies. At √{s }=20 GeV the enhancement factor with respect to the conventional contribution is larger than a factor of five. In the considered picture the large-xF D mesons are produced dominantly via fragmentation of light quarks/antiquarks. Predictions for fixed target p + 4He collisions relevant for a fixed target LHCb experiment are presented.

Regge spectra of excited mesons, harmonic confinement, and QCD vacuum structure

NASA Astrophysics Data System (ADS)

Nedelko, Sergei N.; Voronin, Vladimir E.

2016-05-01

An approach to QCD vacuum as a medium describable in terms of a statistical ensemble of almost everywhere homogeneous Abelian (anti-)self-dual gluon fields is briefly reviewed. These fields play the role of the confining medium for color charged fields as well as underline the mechanism of realization of chiral S UL(Nf)×S UR(Nf) and UA(1 ) symmetries. Hadronization formalism based on this ensemble leads to manifestly defined quantum effective meson action. Strong, electromagnetic, and weak interactions of mesons are represented in the action in terms of nonlocal n -point interaction vertices given by the quark-gluon loops averaged over the background ensemble. New systematic results for the mass spectrum and decay constants of radially excited light, heavy-light mesons, and heavy quarkonia are presented. The interrelation between the present approach, models based on ideas of soft-wall anti-de Sitter/QCD, light-front holographic QCD, and the picture of harmonic confinement is outlined.

Charmonium dissociation in collisions with ϕ mesons in hadronic matter

NASA Astrophysics Data System (ADS)

Ji, Shi-Tao; Xu, Xiao-Ming

2017-02-01

The ϕ-charmonium dissociation reactions in hadronic matter are studied. Unpolarised cross sections for , or , , , or , , or and are calculated in the Born approximation, in the quark-interchange mechanism and with a temperature-dependent quark potential. The potential leads to remarkable temperature dependence of the cross sections. With the cross sections and the ϕ distribution function we calculate the dissociation rates of the charmonia in interactions with the ϕ meson in hadronic matter. The dependence of the rates on temperature and charmonium momentum is relevant to the influence of ϕ mesons on charmonium suppression. Supported by National Natural Science Foundation of China (11175111)

Elastic scattering and particle production in two-prong. pi. /sup -/p interactions at 8 GeV/c

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kitagaki, T.; Tanaka, S.; Yuta, H.

1982-10-01

Results of a high-statistics study of elastic scattering and meson resonances produced by ..pi../sup -/p interactions at 8 GeV/c are presented. Large statistics and small systematic errors permit examination of the complete kinematic region. Total differential cross sections are given for rho/sup 0,-/, f/sup 0/, g/sup 0,-/, ..delta../sup + -/, ..delta../sup 0/, and N* resonances. Spin-density matrix elements and Legendre-polynomial moments are given for rho, f, and ..delta.. resonances. The results for rho/sup 0/ and f/sup 0/ resonances are compared with the predictions of a Regge-pole-exchange model. Properties of the above resonances are compared and discussed. In particular, we presentmore » evidence that the rho/sup 0/ and f/sup 0/ production mechanisms are similar. The similarity of the g/sup 0/ t distribution to that of the rho/sup 0/ and f/sup 0/ suggests a common production mechanism for all three resonances.« less

Nelfinavir induces radiation sensitization in pituitary adenoma cells

PubMed Central

Zeng, Jing; See, Alfred P.; Aziz, Khaled; Thiyagarajan, Saravanan; Salih, Tarek; Gajula, Rajendra P.; Armour, Michael; Phallen, Jillian; Terezakis, Stephanie; Kleinberg, Lawrence; Redmond, Kristen; Hales, Russell K.; Salvatori, Roberto; Quinones-Hinojosa, Alfredo; Tran, Phuoc T.; Lim, Michael

2017-01-01

Pituitary adenomas with local invasion and high secretory activity remain a therapeutic challenge. The HIV protease inhibitor nelfinavir is a radiosensitizer in multiple tumor models. We tested nelfinavir as a radiosensitizer in pituitary adenoma cells in vitro and in vivo. We examined the effect of nelfinavir with radiation on in vitro cell viability, clonogenic survival, apoptosis, prolactin secretion, cell cycle distribution and the PI3K-AKT-mTOR pathway. We evaluated tumor growth delay and confirmed nelfinavir’s effect on the PI3K-AKT-mTOR pathway in a hind-flank model. Nelfinavir sensitized pituitary adenoma cells to ionizing radiation as shown by viability assays and clonogenic assay with an enhancement ratio of 1.2 (p < 0.05). There is increased apoptotic cell death, as determined by annexin-V expression and cleaved caspase-3 levels. Nelfinavir does not affect prolactin secretion or cell cycle distribution. In vivo, untreated tumors reached 4-fold volume in 12 d, 17 d with nelfinavir treatment, 27 d with radiation 6 Gy, and 41 d with nelfinavir plus radiation (one-way ANOVA p < 0.001). Decreased phospho-S6 on protein gel blotting in vitro and immunohistochemistry in vivo demonstrated nelfinavir inhibition of the PI3K-AKT-mTOR pathway. Our data suggests a promising combination therapy with nelfinavir plus radiation in pituitary adenomas, which should be investigated in clinical studies. PMID:21811091

Nelfinavir induces radiation sensitization in pituitary adenoma cells.

PubMed

Zeng, Jing; See, Alfred P; Aziz, Khaled; Thiyagarajan, Saravanan; Salih, Tarek; Gajula, Rajendra P; Armour, Michael; Phallen, Jillian; Terezakis, Stephanie; Kleinberg, Lawrence; Redmond, Kristen; Hales, Russell K; Salvatori, Roberto; Quinones-Hinojosa, Alfredo; Tran, Phuoc T; Lim, Michael

2011-10-01

Pituitary adenomas with local invasion and high secretory activity remain a therapeutic challenge. The HIV protease inhibitor nelfinavir is a radiosensitizer in multiple tumor models. We tested nelfinavir as a radiosensitizer in pituitary adenoma cells in vitro and in vivo. We examined the effect of nelfinavir with radiation on in vitro cell viability, clonogenic survival, apoptosis, prolactin secretion, cell cycle distribution, and the PI3K-AKT-mTOR pathway. We evaluated tumor growth delay and confirmed nelfinavir's effect on the PI3K-AKT-mTOR pathway in a hind-flank model. Nelfinavir sensitized pituitary adenoma cells to ionizing radiation as shown by viability assays and clonogenic assay with an enhancement ratio of 1.2 (p < 0.05). There is increased apoptotic cell death, as determined by annexin-V expression and cleaved caspase-3 levels. Nelfinavir does not affect prolactin secretion or cell cycle distribution. In vivo, untreated tumors reached 4-fold volume in 12 days, 17 days with nelfinavir treatment, 27 days with radiation 6 Gy, and 41 days with nelfinavir plus radiation (one-way ANOVA p < 0.001). Decreased phospho-S6 on Western blotting in vitro and immunohistochemistry in vivo demonstrated nelfinavir inhibition of the PI3K-AKT-mTOR pathway. Our data suggests a promising combination therapy with nelfinavir plus radiation in pituitary adenomas, which should be investigated in clinical studies.

Sigma meson in vacuum and nuclear matter

NASA Astrophysics Data System (ADS)

Menchaca-Maciel, M. C.; Morones-Ibarra, J. R.

2013-04-01

We have obtained the value of the interaction constant g σππ that adjusts the values obtained in the E791 Collaboration at Fermilab and BES Collaboration at the Beijing Electron Positron Collider experiments. To get this we have used the concept of critical width to make compatible the parameters obtained from the Breit-Wigner formula and those obtained from the density function. Also, the total width and effective mass modification of the sigma meson in nuclear matter has been studied in the Walecka model, assuming that the sigma couples to a pair of nucleon-antinucleon states and to particle-hole states, including the in-medium effect of sigma-omega mixing. We have considered, for completeness, the coupling of sigma to two virtual pions. We have found that the sigma meson mass decreases with respect to its value in vacuum and that the contribution of the sigma-omega mixing effect on the mass shift is relevant.

Large-Nc masses of light mesons from QCD sum rules for nonlinear radial Regge trajectories

NASA Astrophysics Data System (ADS)

Afonin, S. S.; Solomko, T. D.

2018-04-01

The large-Nc masses of light vector, axial, scalar and pseudoscalar mesons are calculated from QCD spectral sum rules for a particular ansatz interpolating the radial Regge trajectories. The ansatz includes a linear part plus exponentially degreasing corrections to the meson masses and residues. The form of corrections was proposed some time ago for consistency with analytical structure of Operator Product Expansion of the two-point correlation functions. We revised that original analysis and found the second solution for the proposed sum rules. The given solution describes better the spectrum of vector and axial mesons.

The effect of pharmacological PI3Kγ inhibitor on eotaxin-induced human eosinophil functions.

PubMed

Saito, Yukiko; Takeda, Masahide; Nishikawa, Junko; Konno, Yasunori; Tamaki, Mami; Itoga, Masamichi; Kobayashi, Yoshiki; Moritoki, Yuki; Ito, Wataru; Chihara, Junichi; Ueki, Shigeharu

2014-04-01

Asthma is characterized by chronic inflammation caused by activation of immune cells including Th2 lymphocytes and eosinophils. Phosphoinositide 3-kinase (PI3K) γ deficient asthmatic mice did not develop lung eosinophilia, although the detailed mechanisms are not well known. A CC chemokine eotaxin (CCL11) plays a prominent role in developing eosinophilic inflammation through CCR3. In this study, we tested the roles of PI3Kγ in eotaxin-induced eosinophil functions using a pharmacological inhibitor. Human peripheral blood eosinophils were isolated by CD16-negative selection method. The effect of AS605240, synthetic PI3Kγ inhibitor on eotaxin-induced adhesion, chemotaxis, and degranulation were studied using intracellular adhesion molecule-1 (ICAM-1)-coated plates, Boyden chamber system, ELISA for eosinophil-derived neurotoxin (EDN) levels in the culture supernatant, respectively. CCR3 expression levels and extracellular signal-regulated kinase 1/2 (ERK1/2) phosphorylation were assessed by flowcytometry. Involvement of PI3Kγ in spontaneous apoptosis was studied using flowcytometry. Although AS605240 did not affect the eosinophil spontaneous apoptosis, eotaxin-induced chemotaxis, adhesion to ICAM-1 coated plate, and EDN release were inhibited by AS605240. AS605240 also inhibited the eotaxin-induced ERK1/2 phosphorylation without down-regulation of surface CCR3 expression. These results indicate that PI3Kγ inhibitor attenuates eotaxin-induced eosinophil functions by suppressing the downstream signaling of CCR3 without significant cytotoxicity. PI3Kγ plays an important role in the development of eosinophilic inflammation and blockade of PI3Kγ might be a therapeutic strategy for treatment of eosinophil-related diseases including asthma. Crown Copyright © 2013. Published by Elsevier Ltd. All rights reserved.

Measurement of coherent ϕ-meson photoproduction from the deuteron at low energies

NASA Astrophysics Data System (ADS)

Mibe, T.; Gao, H.; Hicks, K.; Kramer, K.; Stepanyan, S.; Tedeschi, D. J.; Amaryan, M. J.; Ambrozewicz, P.; Anghinolfi, M.; Asryan, G.; Audit, G.; Avakian, H.; Bagdasaryan, H.; Baillie, N.; Ball, J. P.; Baltzell, N. A.; Battaglieri, M.; Bedlinskiy, I.; Bellis, M.; Benmouna, N.; Berman, B. L.; Biselli, A. S.; Blaszczyk, L.; Bouchigny, S.; Boiarinov, S.; Bradford, R.; Branford, D.; Briscoe, W. J.; Brooks, W. K.; Bültmann, S.; Burkert, V. D.; Butuceanu, C.; Calarco, J. R.; Careccia, S. L.; Carman, D. S.; Chen, S.; Cole, P. L.; Collins, P.; Coltharp, P.; Crabb, D.; Crannell, H.; Crede, V.; Cummings, J. P.; Dashyan, N.; Masi, R. De; Vita, R. De; Sanctis, E. De; Degtyarenko, P. V.; Deur, A.; Dharmawardane, K. V.; Dickson, R.; Djalali, C.; Dodge, G. E.; Donnelly, J.; Doughty, D.; Dugger, M.; Dzyubak, O. P.; Egiyan, H.; Egiyan, K. S.; Fassi, L. El; Elouadrhiri, L.; Eugenio, P.; Fedotov, G.; Feldman, G.; Funsten, H.; Garçon, M.; Gavalian, G.; Gilfoyle, G. P.; Giovanetti, K. L.; Girod, F. X.; Goetz, J. T.; Gonenc, A.; Gordon, C. I. O.; Gothe, R. W.; Griffioen, K. A.; Guidal, M.; Guler, N.; Guo, L.; Gyurjyan, V.; Hadjidakis, C.; Hafidi, K.; Hakobyan, H.; Hakobyan, R. S.; Hanretty, C.; Hardie, J.; Hersman, F. W.; Hleiqawi, I.; Holtrop, M.; Hyde-Wright, C. E.; Ilieva, Y.; Ireland, D. G.; Ishkhanov, B. S.; Isupov, E. L.; Ito, M. M.; Jenkins, D.; Jo, H. S.; Johnstone, J. R.; Joo, K.; Juengst, H. G.; Kalantarians, N.; Kellie, J. D.; Khandaker, M.; Kim, W.; Klein, A.; Klein, F. J.; Klimenko, A. V.; Kossov, M.; Krahn, Z.; Kramer, L. H.; Kubarovsky, V.; Kuhn, J.; Kuhn, S. E.; Kuleshov, S. V.; Kuznetsov, V.; Lachniet, J.; Laget, J. M.; Langheinrich, J.; Lawrence, D.; Lee, T.; Li, J.; Livingston, K.; Lu, H. Y.; MacCormick, M.; Marchand, C.; Markov, N.; Mattione, P.; McKinnon, B.; Mecking, B. A.; Melone, J. J.; Mestayer, M. D.; Meyer, C. A.; Mikhailov, K.; Minehart, R.; Mirazita, M.; Miskimen, R.; Mokeev, V.; Moriya, K.; Morrow, S. A.; Moteabbed, M.; Munevar, E.; Mutchler, G. S.; Nadel-Turonski, P.; Nasseripour, R.; Niccolai, S.; Niculescu, G.; Niculescu, I.; Niczyporuk, B. B.; Niroula, M. R.; Niyazov, R. A.; Nozar, M.; Osipenko, M.; Ostrovidov, A. I.; Park, K.; Pasyuk, E.; Paterson, C.; Pereira, S. Anefalos; Pierce, J.; Pivnyuk, N.; Pocanic, D.; Pogorelko, O.; Pozdniakov, S.; Price, J. W.; Prok, Y.; Protopopescu, D.; Raue, B. A.; Riccardi, G.; Ricco, G.; Ripani, M.; Ritchie, B. G.; Ronchetti, F.; Rosner, G.; Rossi, P.; Sabatié, F.; Salamanca, J.; Salgado, C.; Santoro, J. P.; Sapunenko, V.; Schumacher, R. A.; Serov, V. S.; Sharabian, Y. G.; Sharov, D.; Shvedunov, N. V.; Smith, E. S.; Smith, L. C.; Sober, D. I.; Sokhan, D.; Stavinsky, A.; Stepanyan, S. S.; Stokes, B. E.; Stoler, P.; Strakovsky, I. I.; Strauch, S.; Taiuti, M.; Thoma, U.; Tkabladze, A.; Tkachenko, S.; Todor, L.; Tur, C.; Ungaro, M.; Vineyard, M. F.; Vlassov, A. V.; Watts, D. P.; Weinstein, L. B.; Weygand, D. P.; Williams, M.; Wolin, E.; Wood, M. H.; Yegneswaran, A.; Zana, L.; Zhang, J.; Zhao, B.; Zhao, Z. W.

2007-11-01

The cross section and decay angular distributions for the coherent ϕ-meson photoproduction on the deuteron have been measured for the first time up to a squared four-momentum transfer t=(pγ-pϕ)2=-2 GeV2/c2, using the CLAS detector at the Thomas Jefferson National Accelerator Facility. The cross sections are compared with predictions from a rescattering model. In a framework of vector meson dominance, the data are consistent with the total ϕ-N cross section σϕN at about 10 mb. If vector meson dominance is violated, a larger σϕN is possible by introducing a larger t slope for the ϕN→ϕN process than that for the γN→ϕN process. The decay angular distributions of the ϕ are consistent with helicity conservation.

Neutral meson properties under an external magnetic field in nonlocal chiral quark models

NASA Astrophysics Data System (ADS)

Gómez Dumm, D.; Izzo Villafañe, M. F.; Scoccola, N. N.

2018-02-01

We study the behavior of neutral meson properties in the presence of a static uniform external magnetic field in the context of nonlocal chiral quark models. The formalism is worked out introducing Ritus transforms of Dirac fields, which allow to obtain closed analytical expressions for π0 and σ meson masses and for the π0 decay constant. Numerical results for these observables are quoted for various parametrizations. In particular, the behavior of the π0 meson mass with the magnetic field is found to be in good agreement with lattice QCD results. It is also seen that the Goldberger-Treiman and Gell-Mann-Oakes-Renner chiral relations remain valid within these models in the presence of the external magnetic field.

Faddeev calculations of. pi. D scattering

DOE Office of Scientific and Technical Information (OSTI.GOV)