Existing generating assets squeezed as new project starts slow

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jones, R.B.; Tiffany, E.D.

Most forecasting reports concentrate on political or regulatory events to predict future industry trends. Frequently overlooked are the more empirical performance trends of the principal power generation technologies. Solomon and Associates queried its many power plant performance databases and crunched some numbers to identify those trends. Areas of investigation included reliability, utilization (net output factor and net capacity factor) and cost (operating costs). An in-depth analysis for North America and Europe is presented in this article, by region and by regeneration technology. 4 figs., 2 tabs.

Electric power quarterly, July-September 1986

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1987-02-04

The Electric Power Quarterly (EPQ) provides information on electric utilities at the plant level. The information concerns the following: cost, quantity, and quality of fossil fuel receipts; net generation; fuel consumption; and fuel stocks. The EPQ contains monthly data and quarterly totals for the reporting quarter. In this report, data collected on Form EIA-759 regarding electric utilities' net generation, fuel consumption, and fuel stocks are presented on a plant-by-plant basis. In addition, quantity, cost, and quality of fossil fuel receipts collected on the Form 423 are presented on a plant-by-plant basis. The EPQ presents a quarterly summary of disturbances andmore » unusual occurrences affecting the electric power industry collected by the Office of International Affairs and Energy Emergencies (IE) on Form IE-417.« less

Electric power quarterly: January-March 1988. [Contains glossary

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-07-22

The Electric Power Quarterly (EPQ) presents information on electric utilities at the plant level. The information provides the following: cost, quantity, and quality of fossil fuel receipts; net generation; fuel consumption; and fuel stocks. The EPQ contains monthly data and quarterly totals for the reporting quarter. These data are published to provide meaningful, timely, objective, and accurate energy information for a wide audience including Congress, federal, and state agencies; industry; and the general public. In this report, data regarding electric utilities' net generation, fuel consumption, and fuel stocks are presented on a plant-by-plant basis. In addition, quantity, cost, and qualitymore » of fossil-fuel receipts are presented on a plant-by-plant basis for plants with a combined installed nameplate capacity of 50 megawatts or larger.« less

Places to Go: Google's Search Results for "Net Generation"

ERIC Educational Resources Information Center

Downes, Stephen

2007-01-01

In his Places to Go column for a special issue on the Net Generation, Stephen Downes takes an unexpected trip--to Google. According to Downes, Google epitomizes the essence of the Net Generation. Infinitely searchable and adaptable, Google represents the spirit of a generation raised in the world of the Internet, a generation that adapts…

Teaching and Learning with the Net Generation

ERIC Educational Resources Information Center

Barnes, Kassandra; Marateo, Raymond C.; Ferris, S. Pixy

2007-01-01

As the Net Generation places increasingly greater demands on educators, students and teachers must jointly consider innovative ways of teaching and learning. In this, educators are supported by the fact that the Net Generation wants to learn. However, these same educators should not fail to realize that this generation learns differently from…

Attribution of Net Carbon Change by Disturbance Type across Forest Lands of the Continental United States

NASA Astrophysics Data System (ADS)

Hagen, S. C.; Harris, N.; Saatchi, S. S.; Domke, G. M.; Woodall, C. W.; Pearson, T.

2016-12-01

We generated spatially comprehensive maps of carbon stocks and net carbon changes from US forestlands between 2005 and 2010 and attributed the changes to natural and anthropogenic processes. The prototype system created to produce these maps is designed to assist with national GHG inventories and support decisions associated with land management. Here, we present the results and methodological framework of our analysis. In summary, combining estimates of net C losses and gains results in net carbon change of 269±49 Tg C yr-1 (sink) in the coterminous US forest land, with carbon loss from harvest acting as the predominent source process.

Net-generation attributes and seductive properties of the internet as predictors of online activities and internet addiction.

PubMed

Leung, Louis

2004-06-01

Born between 1977 and 1997, Net-generation is the first generation to grow up surrounded by home computers, video games, and the Internet. As children of the Baby Boomers, the Internet is the medium of choice for the Net-geners. Based on the assumption that Net-generation has unique characteristics, this study examined (1) how Net-geners addicted to the Internet differ from the non-addicted and (2) how these attributes, together with the seductive properties of the Internet, are related to Internet addiction. Data were gathered from a probability sample of 699 Net-geners between the ages of 16 and 24. Results show that Net-geners addicted to the Internet tend to be young female students. Being emotionally open on the Net and a heavy user of ICQ were most influential in predicting Net-geners' problematic use of the Internet. Addicted Net-geners are also strongly linked to the pleasure of being able to control the simulated world in online games. The finding reinforces previous research that "dependents" of the Internet spend most of their time in the synchronous communication environment engaging in interactive online games, chat rooms, and ICQ for pleasure-seeking or escape, while "non-dependents" use information-gathering functions available on the Internet. Furthermore, Internet addicts tend to watch television significantly less, indicating a displacement effect on traditional media use for the Net-generation.

Compensation for Distributed Solar. A Survey of Options to Preserve Stakeholder Value

DOE Office of Scientific and Technical Information (OSTI.GOV)

Flores-Espino, Francisco

2015-09-01

Compensation mechanisms for electricity generation systems installed behind the meter are under scrutiny in several jurisdictions in the United States. Legislators in 29 states introduced bills to amend net metering provisions in 2014, and in 33 states in the 2015 legislative session as of August 20, 2015. Some utilities have also sought to increase the revenue they receive from net-metered customers through rate redesign. The circumstances that have triggered the recent push for change include a growing percentage of net-metered customers, potential effects of distributed generation on cost allocation, decreasing photovoltaic (PV) system costs, the challenges of integrating high levelsmore » of solar generation in the distribution network, and increasing pressure on utility business models. This report presents a survey of options to charge and compensate PV customers, as well as options that may preserve utility revenues in scenarios with increased DG. These options could be used as building blocks to create a distributed generation (DG) compensation policy that may preserve the value of the different stakeholders and balance their interests.« less

Long-term field performance of a polyester-based long-lasting insecticidal mosquito net in rural Uganda

PubMed Central

Kilian, Albert; Byamukama, Wilson; Pigeon, Olivier; Atieli, Francis; Duchon, Stephan; Phan, Chi

2008-01-01

Background In order to evaluate whether criteria for LLIN field performance (phase III) set by the WHO Pesticide Evaluation Scheme are met, first and second generations of one of these products, PermaNet®, a polyester net using the coating technology were tested. Methods A randomized, double blinded study design was used comparing LLIN to conventionally treated nets and following LLIN for three years under regular household use in rural conditions. Primary outcome measures were deltamethrin residue and bioassay performance (60 minute knock-down and 24 hour mortality after a three minute exposure) using a strain of Anopheles gambiae s.s. sensitive to pyrethroid insecticides. Results Baseline concentration of deltamethrin was within targets for all net types but was rapidly lost in conventionally treated nets and first generation PermaNet® with median of 0.7 and 2.5 mg/m2 after six months respectively. In contrast, second generation PermaNet® retained insecticide well and had 41.5% of baseline dose after 36 months (28.7 mg/m2). Similarly, vector mortality and knockdown dropped to 18% and 70% respectively for first generation LLIN after six months but remained high (88.5% and 97.8% respectively) for second generation PermaNet® after 36 months of follow up at which time 90.0% of nets had either a knockdown rate ≥ 95% or mortality rate ≥ 80%. Conclusion Second generation PermaNet® showed excellent results after three years of field use and fulfilled the WHOPES criteria for LLIN. Loss of insecticide on LLIN using coating technology under field conditions was far more influenced by factors associated with handling rather than washing. PMID:18355408

Fighting against the dark side of neutrophil extracellular traps in disease: manoeuvres for host protection.

PubMed

Saffarzadeh, Mona; Preissner, Klaus T

2013-01-01

This review presents a concise summary of the role of neutrophil extracellular traps (NET) in several pathological situations associated with adverse effects of NET. Different strategies are indicated to dampen the unfavourable consequences of NET formation and function. A major extracellular antimicrobial mechanism of neutrophils is induced by formation of NET, in which the microorganisms are trapped within the released chromatin from neutrophils and killed by highly concentrated, NET-entangled antimicrobial proteins. In recent years, exaggerated NET formation and the subsequent complications for the host organism have been reported in several pathological conditions. It has been shown that interfering with NET structure and/or components either via DNase to disrupt the DNA backbone of NET or via antihistone approaches to target the major proteins in NET can diminish the pathological symptoms in such diseases. On the basis of the type of the disease and its severity as well as the outcome of NET generation, different therapeutic strategies may be considered to dampen the inauspicious consequences of exaggerated NET formation and function. Applying combinations of compounds that aim to decrease the adverse activity of DNA and NET-associated proteins/enzymes may increase the efficiency of treatment.

Confronting the Technological Pedagogical Knowledge of Finnish Net Generation Student Teachers

ERIC Educational Resources Information Center

Valtonen, Teemu; Pontinen, Susanna; Kukkonen, Jari; Dillon, Patrick; Vaisanen, Pertti; Hacklin, Stina

2011-01-01

The research reported here is concerned with a critical examination of some of the assumptions concerning the "Net Generation" capabilities of 74 first-year student teachers in a Finnish university. There are assumptions that: (i) Net Generation students are adept at learning through discovery and thinking in a hypertext-like manner…

Liveness-enforcing supervisors synthesis for a class of generalised Petri nets based on two-stage deadlock control and mathematical programming

NASA Astrophysics Data System (ADS)

Zhao, Mi; Hou, Yifan; Liu, Ding

2010-10-01

In this article we deal with deadlock prevention problems for S4PR, a class of generalised Petri nets, which can well model a large class of flexible manufacturing systems where deadlocks are caused by insufficiently marked siphons. We present a deadlock prevention methodology that is an iterative approach consisting of two stages. The first one is called siphon control, which is to add for each insufficiently marked minimal siphon a control place to the original net. Its objective is to prevent a minimal siphon from being insufficiently marked. The second one, called control-induced siphon control, is to add a control place to the augmented net with its output arcs connecting to the source transitions, which assures that there are no new insufficiently marked siphons generated. At each iteration, a mixed integer programming approach is adopted for generalised Petri nets to obtain an insufficiently marked minimal siphon from the maximal deadly siphon. This way complete siphon enumeration is avoided that is much more time-consuming for a sizeable plant model than the proposed method. The relation of the proposed method and the liveness and reversibility of the controlled net is obtained. Examples are presented to demonstrate the presented method.

An Extensible NetLogo Model for Visualizing Message Routing Protocols

DTIC Science & Technology

2017-08-01

the hard sciences to the social sciences to computer-generated art. NetLogo represents the world as a set of...describe the model is shown here; for the supporting methods , refer to the source code. Approved for public release; distribution is unlimited. 4 iv...if ticks - last-inject > time-to-inject [inject] if run# > #runs [stop] end Next, we present some basic statistics collected for the

BioNetSim: a Petri net-based modeling tool for simulations of biochemical processes.

PubMed

Gao, Junhui; Li, Li; Wu, Xiaolin; Wei, Dong-Qing

2012-03-01

BioNetSim, a Petri net-based software for modeling and simulating biochemistry processes, is developed, whose design and implement are presented in this paper, including logic construction, real-time access to KEGG (Kyoto Encyclopedia of Genes and Genomes), and BioModel database. Furthermore, glycolysis is simulated as an example of its application. BioNetSim is a helpful tool for researchers to download data, model biological network, and simulate complicated biochemistry processes. Gene regulatory networks, metabolic pathways, signaling pathways, and kinetics of cell interaction are all available in BioNetSim, which makes modeling more efficient and effective. Similar to other Petri net-based softwares, BioNetSim does well in graphic application and mathematic construction. Moreover, it shows several powerful predominances. (1) It creates models in database. (2) It realizes the real-time access to KEGG and BioModel and transfers data to Petri net. (3) It provides qualitative analysis, such as computation of constants. (4) It generates graphs for tracing the concentration of every molecule during the simulation processes.

Electric Power Quarterly, January-March 1983

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1983-07-01

The Electric Power Quarterly (EPQ), a new series in the EIA statistical publications, provides electric utilities' plant-level information about the cost, quantity, and quality of fossil fuel receipts, net generation, fuel consumption and fuel stocks. The EPQ contains monthly data and quarterly totals for the reporting quarter. The data presented in this report were collected and published by the EIA to fulfill its responsibilities as specified in the Federal Energy Administration Act of 1974 (P.L. 93-275). This edition of the EPQ contains monthly data for the first quarter of 1983. In this report, data collected on Form EIA-759 regarding electricmore » utilities' net generation, fuel consumption, and fuel stocks are presented for the first time on a plant-by-plant basis. In addition, quantity, cost, and quality of fossil fuel receipts collected on the Federal Energy Regulatory Commission (FERC) Form 423 are presented on a plant-by-plant basis.« less

Erythrocyte-derived optical nano-vesicles as theranostic agents

NASA Astrophysics Data System (ADS)

Mac, Jenny T.; Nunez, Vicente; Bahmani, Baharak; Guerrero, Yadir; Tang, Jack; Vullev, Valentine I.; Anvari, Bahman

2015-07-01

We have engineered nano-vesicles, derived from erythrocytes, which can be doped with various near infrared (NIR) organic chromophores, including the FDA-approved indocyanine green (ICG). We refer to these vesicles as NIR erythrocyte-mimicking transducers (NETS) since in response to NIR photo-excitation they can generate heat or emit fluorescent light. Using biochemical methods based on reduction amination, we have functionalized the surface of NET with antibodies to target specific biomolecules. We present results that demonstrate the effectiveness of NETs in targeted imaging of cancer cells that over-express the human epidermal growth factor receptor-2 (HER2).

C code generation from Petri-net-based logic controller specification

NASA Astrophysics Data System (ADS)

Grobelny, Michał; Grobelna, Iwona; Karatkevich, Andrei

2017-08-01

The article focuses on programming of logic controllers. It is important that a programming code of a logic controller is executed flawlessly according to the primary specification. In the presented approach we generate C code for an AVR microcontroller from a rule-based logical model of a control process derived from a control interpreted Petri net. The same logical model is also used for formal verification of the specification by means of the model checking technique. The proposed rule-based logical model and formal rules of transformation ensure that the obtained implementation is consistent with the already verified specification. The approach is validated by practical experiments.

Spurious symptom reduction in fault monitoring

NASA Technical Reports Server (NTRS)

Shontz, William D.; Records, Roger M.; Choi, Jai J.

1993-01-01

Previous work accomplished on NASA's Faultfinder concept suggested that the concept was jeopardized by spurious symptoms generated in the monitoring phase. The purpose of the present research was to investigate methods of reducing the generation of spurious symptoms during in-flight engine monitoring. Two approaches for reducing spurious symptoms were investigated. A knowledge base of rules was constructed to filter known spurious symptoms and a neural net was developed to improve the expectation values used in the monitoring process. Both approaches were effective in reducing spurious symptoms individually. However, the best results were obtained using a hybrid system combining the neural net capability to improve expectation values with the rule-based logic filter.

Petri net modeling of high-order genetic systems using grammatical evolution.

PubMed

Moore, Jason H; Hahn, Lance W

2003-11-01

Understanding how DNA sequence variations impact human health through a hierarchy of biochemical and physiological systems is expected to improve the diagnosis, prevention, and treatment of common, complex human diseases. We have previously developed a hierarchical dynamic systems approach based on Petri nets for generating biochemical network models that are consistent with genetic models of disease susceptibility. This modeling approach uses an evolutionary computation approach called grammatical evolution as a search strategy for optimal Petri net models. We have previously demonstrated that this approach routinely identifies biochemical network models that are consistent with a variety of genetic models in which disease susceptibility is determined by nonlinear interactions between two DNA sequence variations. In the present study, we evaluate whether the Petri net approach is capable of identifying biochemical networks that are consistent with disease susceptibility due to higher order nonlinear interactions between three DNA sequence variations. The results indicate that our model-building approach is capable of routinely identifying good, but not perfect, Petri net models. Ideas for improving the algorithm for this high-dimensional problem are presented.

ICU early physical rehabilitation programs: financial modeling of cost savings.

PubMed

Lord, Robert K; Mayhew, Christopher R; Korupolu, Radha; Mantheiy, Earl C; Friedman, Michael A; Palmer, Jeffrey B; Needham, Dale M

2013-03-01

To evaluate the potential annual net cost savings of implementing an ICU early rehabilitation program. Using data from existing publications and actual experience with an early rehabilitation program in the Johns Hopkins Hospital Medical ICU, we developed a model of net financial savings/costs and presented results for ICUs with 200, 600, 900, and 2,000 annual admissions, accounting for both conservative- and best-case scenarios. Our example scenario provided a projected financial analysis of the Johns Hopkins Medical ICU early rehabilitation program, with 900 admissions per year, using actual reductions in length of stay achieved by this program. U.S.-based adult ICUs. Financial modeling of the introduction of an ICU early rehabilitation program. Net cost savings generated in our example scenario, with 900 annual admissions and actual length of stay reductions of 22% and 19% for the ICU and floor, respectively, were $817,836. Sensitivity analyses, which used conservative- and best-case scenarios for length of stay reductions and varied the per-day ICU and floor costs, across ICUs with 200-2,000 annual admissions, yielded financial projections ranging from -$87,611 (net cost) to $3,763,149 (net savings). Of the 24 scenarios included in these sensitivity analyses, 20 (83%) demonstrated net savings, with a relatively small net cost occurring in the remaining four scenarios, mostly when simultaneously combining the most conservative assumptions. A financial model, based on actual experience and published data, projects that investment in an ICU early rehabilitation program can generate net financial savings for U.S. hospitals. Even under the most conservative assumptions, the projected net cost of implementing such a program is modest relative to the substantial improvements in patient outcomes demonstrated by ICU early rehabilitation programs.

THE ORIGIN OF NET ELECTRIC CURRENTS IN SOLAR ACTIVE REGIONS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dalmasse, K.; Aulanier, G.; Démoulin, P.

There is a recurring question in solar physics regarding whether or not electric currents are neutralized in active regions (ARs). This question was recently revisited using three-dimensional (3D) magnetohydrodynamic (MHD) numerical simulations of magnetic flux emergence into the solar atmosphere. Such simulations showed that flux emergence can generate a substantial net current in ARs. Other sources of AR currents are photospheric horizontal flows. Our aim is to determine the conditions for the occurrence of net versus neutralized currents with this second mechanism. Using 3D MHD simulations, we systematically impose line-tied, quasi-static, photospheric twisting and shearing motions to a bipolar potentialmore » magnetic field. We find that such flows: (1) produce both direct and return currents, (2) induce very weak compression currents—not observed in 2.5D—in the ambient field present in the close vicinity of the current-carrying field, and (3) can generate force-free magnetic fields with a net current. We demonstrate that neutralized currents are in general produced only in the absence of magnetic shear at the photospheric polarity inversion line—a special condition that is rarely observed. We conclude that  photospheric flows, as magnetic flux emergence, can build up net currents in the solar atmosphere, in agreement with recent observations. These results thus provide support for eruption models based on pre-eruption magnetic fields that possess a net coronal current.« less

IPMC-driven thrust generation: a new conceptual design (Conference Presentation)

NASA Astrophysics Data System (ADS)

Olsen, Zakai; Kim, Kwang Jin

2017-04-01

Ionic Polymer-Metal Composites (IPMC) are highly functional actuators that find many uses in the field of soft robotics due to their low actuation voltage and ability to operate in aquatic environments. The actuation of an IPMC relies on the swelling of the negatively charged side when a potential is applied, due to the free-moving cations and water molecules migrating to that half. While this bending type actuation can be utilized to perform many tasks, it is ill suited for the primary propulsion mechanism in certain soft robotic applications. Here, a new conceptual design is presented which utilizes the bending of IPMC materials to achieve complex actuation motion in an attempt to generate a non-zero net thrust for propulsion of soft robots. The design capitalizes on advances in the manufacturing processes of electroactive polymer materials, which now allow for more complex shapes and thus new and unique modes of actuation. By utilizing the consistent bending deformation of IPMC actuators, in conjunction with carefully considered geometry, an IPMC driven body may serve as a primary mode of propulsion through a positive net thrust generation. This work consists of the initial feasibility study, concept testing, and optimization for such an actuator through computer modeling and simulation. COMSOL will be used for the finite element analysis to design the most efficient and optimized design for a positive net thrust generation. Such an IPMC design may find a great deal of applications, and the potential of future integration into other soft robotic systems is considered.

Equity of tolling : myths and realities

DOT National Transportation Integrated Search

2010-02-26

This presentation discusses the equity and efficiency of tolling and the increases in efficiency from efficiency gains. Efficiency and equity are inextricably related, and they are not inherently in conflict. Congestion pricing generates positive net...

Light-based theranostics using hybrid structures derived from biological and organic materials

NASA Astrophysics Data System (ADS)

Vankayala, Raviraj; Burns, Joshua M.; Mac, Jenny T.; Anvari, Bahman

2016-09-01

We have engineered hybrid nanostructures derived from erythrocytes, which can be doped with various near infrared (NIR) organic chromophores, including the FDA-approved indocyanine green (ICG). We refer to these vesicles as NIR erythrocyte-mimicking transducers (NETs), as they are capable of generating heat, reactive oxygen species (ROS) or emit fluorescence light. We present preliminary results that demonstrate the effectiveness of NETs for fluorescence imaging and photodynamic therapeutic destruction of breast cancer cells, upon photo-excitation using NIR light. These hybrid nanostructures present a promising platform with theranostic capability for future biomedical clinical applications.

NetList(+): A simple interface language for chip design

NASA Astrophysics Data System (ADS)

Wuu, Tzyh-Yung

1991-04-01

NetList (+) is a design specification language developed at MOSIS for rapid turn-around cell-based ASIC prototyping. By using NetList (+), a uniform representation is achieved for the specification, simulation, and physical description of a design. The goal is to establish an interfacing methodology between design specification and independent computer aided design tools. Designers need only to specify a system by writing a corresponding netlist. This netlist is used for both functional simulation and timing simulation. The same netlist is also used to derive the low level physical tools to generate layout. Another goal of using NetList (+) is to generate parts of a design by running it through different kinds of placement and routing (P and R) tools. For example some parts of a design will be generated by standard cell P and R tools. Other parts may be generated by a layout tiler; i.e., datapath compiler, RAM/ROM generator, or PLA generator. Finally all different parts of a design can be integrated by general block P and R tools as a single chip. The NetList (+) language can actually act as an interface among tools. Section 2 shows a flowchart to illustrate the NetList (+) system and its relation with other related design tools. Section 3 shows how to write a NetList (+) description from the block diagram of a circuit. In section 4 discusses how to prepare a cell library or several cell libraries for a design system. Section 5 gives a few designs by NetList (+) and shows their simulation and layout results.

The HLA-net GENE[RATE] pipeline for effective HLA data analysis and its application to 145 population samples from Europe and neighbouring areas.

PubMed

Nunes, J M; Buhler, S; Roessli, D; Sanchez-Mazas, A

2014-05-01

In this review, we present for the first time an integrated version of the Gene[rate] computer tools which have been developed during the last 5 years to analyse human leukocyte antigen (HLA) data in human populations, as well as the results of their application to a large dataset of 145 HLA-typed population samples from Europe and its two neighbouring areas, North Africa and West Asia, now forming part of the Gene[va] database. All these computer tools and genetic data are, from now, publicly available through a newly designed bioinformatics platform, HLA-net, here presented as a main achievement of the HLA-NET scientific programme. The Gene[rate] pipeline offers user-friendly computer tools to estimate allele and haplotype frequencies, to test Hardy-Weinberg equilibrium (HWE), selective neutrality and linkage disequilibrium, to recode HLA data, to convert file formats, to display population frequencies of chosen alleles and haplotypes in selected geographic regions, and to perform genetic comparisons among chosen sets of population samples, including new data provided by the user. Both numerical and graphical outputs are generated, the latter being highly explicit and of publication quality. All these analyses can be performed on the pipeline after scrupulous validation of the population sample's characterisation and HLA typing reporting according to HLA-NET recommendations. The Gene[va] database offers direct access to the HLA-A, -B, -C, -DQA1, -DQB1, -DRB1 and -DPB1 frequencies and summary statistics of 145 population samples having successfully passed these HLA-NET 'filters', and representing three European subregions (South-East, North-East and Central-West Europe) and two neighbouring areas (North Africa, as far as Sudan, and West Asia, as far as South India). The analysis of these data, summarized in this review, shows a substantial genetic variation at the regional level in this continental area. These results have main implications for population genetics, transplantation and epidemiological studies. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Optimization of Training Sets for Neural-Net Processing of Characteristic Patterns from Vibrating Solids

NASA Technical Reports Server (NTRS)

Decker, Arthur J.

2001-01-01

Artificial neural networks have been used for a number of years to process holography-generated characteristic patterns of vibrating structures. This technology depends critically on the selection and the conditioning of the training sets. A scaling operation called folding is discussed for conditioning training sets optimally for training feed-forward neural networks to process characteristic fringe patterns. Folding allows feed-forward nets to be trained easily to detect damage-induced vibration-displacement-distribution changes as small as 10 nm. A specific application to aerospace of neural-net processing of characteristic patterns is presented to motivate the conditioning and optimization effort.

Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals.

PubMed

Hazeldine, Jon; Harris, Phillipa; Chapple, Iain L; Grant, Melissa; Greenwood, Hannah; Livesey, Amy; Sapey, Elizabeth; Lord, Janet M

2014-08-01

Neutrophil extracellular traps (NETs) are a recently discovered addition to the defensive armamentarium of neutrophils, assisting in the immune response against rapidly dividing bacteria. Although older adults are more susceptible to such infections, no study has examined whether aging in humans influences NET formation. We report that TNF-α-primed neutrophils generate significantly more NETs than unprimed neutrophils and that lipopolysaccharide (LPS)- and interleukin-8 (IL-8)-induced NET formation exhibits a significant age-related decline. NET formation requires generation of reactive oxygen species (ROS), and this was also reduced in neutrophils from older donors identifying a mechanism for reduced NET formation. Expression of IL-8 receptors (CXCR1 and CXCR2) and the LPS receptor TLR4 was similar on neutrophils from young and old subjects, and neutrophils challenged with phorbol-12-myristate-13-acetate (PMA) showed no age-associated differences in ROS or NET production. Taken together, these data suggest a defect in proximal signalling underlies the age-related decline in NET and ROS generation. TNF-α priming involves signalling through p38 MAP kinase, but activation kinetics were comparable in neutrophils from young and old donors. In a clinical setting, we assessed the capacity of neutrophils from young and older patients with chronic periodontitis to generate NETs in response to PMA and hypochlorous acid (HOCL). Neutrophil extracellular trap generation to HOCL, but not PMA, was lower in older periodontitis patients but not in comparison with age-matched controls. Impaired NET formation is thus a novel defect of innate immunity in older adults but does not appear to contribute to the increased incidence of periodontitis in older adults. © 2014 The Authors. Aging Cell published by the Anatomical Society and John Wiley & Sons Ltd.

Impaired neutrophil extracellular trap formation: a novel defect in the innate immune system of aged individuals

PubMed Central

Hazeldine, Jon; Harris, Phillipa; Chapple, Iain L; Grant, Melissa; Greenwood, Hannah; Livesey, Amy; Sapey, Elizabeth; Lord, Janet M

2014-01-01

Neutrophil extracellular traps (NETs) are a recently discovered addition to the defensive armamentarium of neutrophils, assisting in the immune response against rapidly dividing bacteria. Although older adults are more susceptible to such infections, no study has examined whether aging in humans influences NET formation. We report that TNF-α-primed neutrophils generate significantly more NETs than unprimed neutrophils and that lipopolysaccharide (LPS)- and interleukin-8 (IL-8)-induced NET formation exhibits a significant age-related decline. NET formation requires generation of reactive oxygen species (ROS), and this was also reduced in neutrophils from older donors identifying a mechanism for reduced NET formation. Expression of IL-8 receptors (CXCR1 and CXCR2) and the LPS receptor TLR4 was similar on neutrophils from young and old subjects, and neutrophils challenged with phorbol-12-myristate-13-acetate (PMA) showed no age-associated differences in ROS or NET production. Taken together, these data suggest a defect in proximal signalling underlies the age-related decline in NET and ROS generation. TNF-α priming involves signalling through p38 MAP kinase, but activation kinetics were comparable in neutrophils from young and old donors. In a clinical setting, we assessed the capacity of neutrophils from young and older patients with chronic periodontitis to generate NETs in response to PMA and hypochlorous acid (HOCL). Neutrophil extracellular trap generation to HOCL, but not PMA, was lower in older periodontitis patients but not in comparison with age-matched controls. Impaired NET formation is thus a novel defect of innate immunity in older adults but does not appear to contribute to the increased incidence of periodontitis in older adults. PMID:24779584

Small Boat and Swarm Defense: A Gap Study

DTIC Science & Technology

2008-09-01

25 1. Java......................................................................................................25 2. The NetBeans ...Figure 12. Overview of Java program development (Zakhour 2006)...............................26 Figure 13. NetBeans IDE generating new “Hello World...Application (Zakhour 2006) ..27 Figure 14. Example source code generation using NetBeans for the “Hello World” application (Zakhour 2006

Task sequence planning in a robot workcell using AND/OR nets

NASA Technical Reports Server (NTRS)

Cao, Tiehua; Sanderson, Arthur C.

1991-01-01

An approach to task sequence planning for a generalized robotic manufacturing or material handling workcell is described. Given the descriptions of the objects in this system and all feasible geometric relationships among these objects, an AND/OR net which describes the relationships of all feasible geometric states and associated feasibility criteria for net transitions is generated. This AND/OR net is mapped into a Petri net which incorporates all feasible sequences of operations. The resulting Petri net is shown to be bounded and have guaranteed properties of liveness, safeness, and reversibility. Sequences are found from the reachability tree of the Petri net. Feasibility criteria for net transitions may be used to generate an extended Petri net representation of lower level command sequences. The resulting Petri net representation may be used for on-line scheduling and control of the system of feasible sequences. A simulation example of the sequences is described.

Optoelectronic analogs of self-programming neural nets - Architecture and methodologies for implementing fast stochastic learning by simulated annealing

NASA Technical Reports Server (NTRS)

Farhat, Nabil H.

1987-01-01

Self-organization and learning is a distinctive feature of neural nets and processors that sets them apart from conventional approaches to signal processing. It leads to self-programmability which alleviates the problem of programming complexity in artificial neural nets. In this paper architectures for partitioning an optoelectronic analog of a neural net into distinct layers with prescribed interconnectivity pattern to enable stochastic learning by simulated annealing in the context of a Boltzmann machine are presented. Stochastic learning is of interest because of its relevance to the role of noise in biological neural nets. Practical considerations and methodologies for appreciably accelerating stochastic learning in such a multilayered net are described. These include the use of parallel optical computing of the global energy of the net, the use of fast nonvolatile programmable spatial light modulators to realize fast plasticity, optical generation of random number arrays, and an adaptive noisy thresholding scheme that also makes stochastic learning more biologically plausible. The findings reported predict optoelectronic chips that can be used in the realization of optical learning machines.

Tidal asymmetry and residual circulation over linear sandbanks and their implication on sediment transport: a process-oriented numerical study

USGS Publications Warehouse

Sanay, Rosario; Voulgaris, George; Warner, John C.

2007-01-01

A series of process-oriented numerical simulations is carried out in order to evaluate the relative role of locally generated residual flow and overtides on net sediment transport over linear sandbanks. The idealized bathymetry and forcing are similar to those present in the Norfolk Sandbanks, North Sea. The importance of bottom drag parameterization and bank orientation with respect to the ambient flow is examined in terms of residual flow and overtide generation, and subsequent sediment transport implications are discussed. The results show that although the magnitudes of residual flow and overtides are sensitive to bottom roughness parameterization and bank orientation, the magnitude of the generated residual flow is always larger than that of the locally generated overtides. Also, net sediment transport is always dominated by the nonlinear interaction of the residual flow and the semidiurnal tidal currents, although cross-bank sediment transport can occur even in the absence of a cross-shore residual flow. On the other hand, net sediment divergence/convergence increases as the bottom drag decreases and as bank orientation increases. The sediment erosion/deposition is not symmetric about the crest of the bank, suggesting that originally symmetric banks would have the tendency to become asymmetric.

The Net Generation, the Internet, and Political Communication and Participation

ERIC Educational Resources Information Center

Velicki, Damir; Dumancic, Mario; Topolovcan, Tomislav

2017-01-01

The Net Generation, a generation which grew up with digital media, differs from older generations which entered the world of digital media and the Internet afterwards. The Internet itself opened new possibilities of communication and participation in the sphere of politics as well. Research was conducted among students at the Faculty of Teacher…

Reviewing the Need for Gaming in Education to Accommodate the Net Generation

ERIC Educational Resources Information Center

Bekebrede, G.; Warmelink, H. J. G.; Mayer, I. S.

2011-01-01

There is a growing interest in the use of simulations and games in Dutch higher education. This development is based on the perception that students belong to the "gamer generation" or "net generation": a generation that has grown up with computer games and other technology affecting their preferred learning styles, social…

Father Google and Mother IM: Confessions of a Net Gen Learner

ERIC Educational Resources Information Center

Windham, Carie

2005-01-01

To bridge the technology cultural gap between many faculty and administrators and the youngest generation of college students, this author, a recent graduate, reveals what being a "Net Gener" really means and how that can translate to the classroom. She discusses what she considers the basic principles that guide the Net Generation: (1)…

Remembering Differently: Use of Memory Strategies among Net-Generation ESL Learners

ERIC Educational Resources Information Center

Shakarami, Alireza; Mardziah, H. Abdullah; Faiz, S. Abdullah; Tan, Bee Hoon

2011-01-01

Net-generation learners are growing up in an era when much of the learning, communication, socializing and ways of working take place through digital means. Living in this digital era may result in different ways of thinking, ways of approaching learning, strategies, and priorities. The Net-Geners therefore, need new skills and new strategies to…

A Vision for the Net Generation Media Center. Media Matters

ERIC Educational Resources Information Center

Johnson, Doug

2005-01-01

Many children today have never lived in a home without a computer. They are the "Net Generation," constantly "connected" by iPod, cell phone, keyboard, digital video camera, or game controller to various technologies. Recent studies have found that Net Genners see technology as "embedded in society," a primary means of connection with friends, and…

Electric power quarterly, April-June 1987

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1987-10-13

The EPQ presents monthly summaries of electric utility statistics at the national, divisional, state, company, and plant levels on the following subjects: quantity of fuel, cost of fuel, quality of fuel, net generation, fuel consumption, fuel stocks. In addition, the EPQ presents a quarterly summary of reported major disturbances and unusual occurrences. These data are collected on the Form IE-417R. Every electric utility engaged in the generation, transmission, or distribution of electric energy must file a report with DOE if it experiences a major power system emergency.

Electric power quarterly, July-September 1987

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-01-22

The EPQ presents monthly summaries of electric utility statistics at the national, divisional, state, company, and plant levels on the following subjects: quantity of fuel, cost of fuel, quality of fuel, net generation, fuel consumption, fuel stocks. In addition, the EPQ presents a quarterly summary of reported major disturbances and unusual occurrences. These data are collected on the Form IE-417R. Every electric utility engaged in the generation, transmission, or distribution of electric energy must file a report with DOE if it experiences a major power system emergency.

A study of sound generation in subsonic rotors, volume 1

NASA Technical Reports Server (NTRS)

Chalupnik, J. D.; Clark, L. T.

1975-01-01

A model for the prediction of wake related sound generation by a single airfoil is presented. It is assumed that the net force fluctuation on an airfoil may be expressed in terms of the net momentum fluctuation in the near wake of the airfoil. The forcing function for sound generation depends on the spectra of the two point velocity correlations in the turbulent region near the airfoil trailing edge. The spectra of the two point velocity correlations were measured for the longitudinal and transverse components of turbulence in the wake of a 91.4 cm chord airfoil. A scaling procedure was developed using the turbulent boundary layer thickness. The model was then used to predict the radiated sound from a 5.1 cm chord airfoil. Agreement between the predicted and measured sound radiation spectra was good. The single airfoil results were extended to a rotor geometry, and various aerodynamic parameters were studied.

[Establishment and evaluation of an in vitro method for neutrophil extracellular trap generation and degradation].

PubMed

Li, Jinlong; Zhang, Yidan; Zhou, Xin; Ji, Wenjie; Zhao, Jihong; Wei, Luqing; Li, Yuming

2014-09-01

To evaluate a novel method for in vitro generation and degradation of neutrophil extracellular traps (NETs), which are a newly recognized structure that is involved in the pathogenesis of autoimmune diseases and thrombosis. Neutrophils from peripheral blood of healthy donors were obtained by Ficoll-Histopaque gradient separation. NET release was initiated by phorbol myristate acetate (PMA) and validated by immunofluorescence staining and agarose gel electrophoresis. NETs degraded by DNase I and healthy human plasma were quantified by fluorescence spectrometry after staining with PicoGreen. HE staining showed that the purity of neutrophils was up to 95% after Ficoll-Histopaque gradient separation. NET immunofluorescent staining revealed that the network structure was mainly composed of DNA and histones, with molecular length more than 10 kb as demonstrated by agarose gel electrophoresis. Moreover, both DNase and healthy human plasma could induce the degradation of NETs, in varying degrees. This work established an efficient method for in vitro generation and degradation of human NETs.

NetProt: Complex-based Feature Selection.

PubMed

Goh, Wilson Wen Bin; Wong, Limsoon

2017-08-04

Protein complex-based feature selection (PCBFS) provides unparalleled reproducibility with high phenotypic relevance on proteomics data. Currently, there are five PCBFS paradigms, but not all representative methods have been implemented or made readily available. To allow general users to take advantage of these methods, we developed the R-package NetProt, which provides implementations of representative feature-selection methods. NetProt also provides methods for generating simulated differential data and generating pseudocomplexes for complex-based performance benchmarking. The NetProt open source R package is available for download from https://github.com/gohwils/NetProt/releases/ , and online documentation is available at http://rpubs.com/gohwils/204259 .

Nematode.net update 2011: addition of data sets and tools featuring next-generation sequencing data

PubMed Central

Martin, John; Abubucker, Sahar; Heizer, Esley; Taylor, Christina M.; Mitreva, Makedonka

2012-01-01

Nematode.net (http://nematode.net) has been a publicly available resource for studying nematodes for over a decade. In the past 3 years, we reorganized Nematode.net to provide more user-friendly navigation through the site, a necessity due to the explosion of data from next-generation sequencing platforms. Organism-centric portals containing dynamically generated data are available for over 56 different nematode species. Next-generation data has been added to the various data-mining portals hosted, including NemaBLAST and NemaBrowse. The NemaPath metabolic pathway viewer builds associations using KOs, rather than ECs to provide more accurate and fine-grained descriptions of proteins. Two new features for data analysis and comparative genomics have been added to the site. NemaSNP enables the user to perform population genetics studies in various nematode populations using next-generation sequencing data. HelmCoP (Helminth Control and Prevention) as an independent component of Nematode.net provides an integrated resource for storage, annotation and comparative genomics of helminth genomes to aid in learning more about nematode genomes, as well as drug, pesticide, vaccine and drug target discovery. With this update, Nematode.net will continue to realize its original goal to disseminate diverse bioinformatic data sets and provide analysis tools to the broad scientific community in a useful and user-friendly manner. PMID:22139919

How to Create "Thriller" PowerPoints[R] in the Classroom!

ERIC Educational Resources Information Center

Berk, Ronald A.

2012-01-01

PowerPoint[R] presentations in academia have a reputation for being less than engaging in this era of learner-centered teaching. The Net Generation also presents a formidable challenge to using PowerPoint[R]. Although the research on the basic elements is rather sparse, the multimedia elements of movement, music, and videos have a stronger…

Next generation tools for genomic data generation, distribution, and visualization

PubMed Central

2010-01-01

Background With the rapidly falling cost and availability of high throughput sequencing and microarray technologies, the bottleneck for effectively using genomic analysis in the laboratory and clinic is shifting to one of effectively managing, analyzing, and sharing genomic data. Results Here we present three open-source, platform independent, software tools for generating, analyzing, distributing, and visualizing genomic data. These include a next generation sequencing/microarray LIMS and analysis project center (GNomEx); an application for annotating and programmatically distributing genomic data using the community vetted DAS/2 data exchange protocol (GenoPub); and a standalone Java Swing application (GWrap) that makes cutting edge command line analysis tools available to those who prefer graphical user interfaces. Both GNomEx and GenoPub use the rich client Flex/Flash web browser interface to interact with Java classes and a relational database on a remote server. Both employ a public-private user-group security model enabling controlled distribution of patient and unpublished data alongside public resources. As such, they function as genomic data repositories that can be accessed manually or programmatically through DAS/2-enabled client applications such as the Integrated Genome Browser. Conclusions These tools have gained wide use in our core facilities, research laboratories and clinics and are freely available for non-profit use. See http://sourceforge.net/projects/gnomex/, http://sourceforge.net/projects/genoviz/, and http://sourceforge.net/projects/useq. PMID:20828407

Validation results of satellite mock-up capturing experiment using nets

NASA Astrophysics Data System (ADS)

Medina, Alberto; Cercós, Lorenzo; Stefanescu, Raluca M.; Benvenuto, Riccardo; Pesce, Vincenzo; Marcon, Marco; Lavagna, Michèle; González, Iván; Rodríguez López, Nuria; Wormnes, Kjetil

2017-05-01

The PATENDER activity (Net parametric characterization and parabolic flight), funded by the European Space Agency (ESA) via its Clean Space initiative, was aiming to validate a simulation tool for designing nets for capturing space debris. This validation has been performed through a set of different experiments under microgravity conditions where a net was launched capturing and wrapping a satellite mock-up. This paper presents the architecture of the thrown-net dynamics simulator together with the set-up of the deployment experiment and its trajectory reconstruction results on a parabolic flight (Novespace A-310, June 2015). The simulator has been implemented within the Blender framework in order to provide a highly configurable tool, able to reproduce different scenarios for Active Debris Removal missions. The experiment has been performed over thirty parabolas offering around 22 s of zero-g conditions. Flexible meshed fabric structure (the net) ejected from a container and propelled by corner masses (the bullets) arranged around its circumference have been launched at different initial velocities and launching angles using a pneumatic-based dedicated mechanism (representing the chaser satellite) against a target mock-up (the target satellite). High-speed motion cameras were recording the experiment allowing 3D reconstruction of the net motion. The net knots have been coloured to allow the images post-process using colour segmentation, stereo matching and iterative closest point (ICP) for knots tracking. The final objective of the activity was the validation of the net deployment and wrapping simulator using images recorded during the parabolic flight. The high-resolution images acquired have been post-processed to determine accurately the initial conditions and generate the reference data (position and velocity of all knots of the net along its deployment and wrapping of the target mock-up) for the simulator validation. The simulator has been properly configured according to the parabolic flight scenario, and executed in order to generate the validation data. Both datasets have been compared according to different metrics in order to perform the validation of the PATENDER simulator.

The physical therapy clinical research network (PTClinResNet): methods, efficacy, and benefits of a rehabilitation research network.

PubMed

Winstein, Carolee; Pate, Patricia; Ge, Tingting; Ervin, Carolyn; Baurley, James; Sullivan, Katherine J; Underwood, Samantha J; Fowler, Eileen G; Mulroy, Sara; Brown, David A; Kulig, Kornelia; Gordon, James; Azen, Stanley P

2008-11-01

This article describes the vision, methods, and implementation strategies used in building the infrastructure for PTClinResNet, a clinical research network designed to assess outcomes for health-related mobility associated with evidence-based physical therapy interventions across and within four different disability groups. Specific aims were to (1) create the infrastructure necessary to develop and sustain clinical trials research in rehabilitation, (2) generate evidence to evaluate the efficacy of resistance exercise-based physical interventions designed to improve muscle performance and movement skills, and (3) provide education and training opportunities for present and future clinician-researchers and for the rehabilitation community at-large in its support of evidence-based practice. We present the network's infrastructure, development, and several examples that highlight the benefits of a clinical research network. We suggest that the network structure is ideal for building research capacity and fostering multisite, multiinvestigator clinical research projects designed to generate evidence for the efficacy of rehabilitation interventions.

Electric power quarterly, October-December 1987

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-04-19

The EPQ presents monthly summaries of electric utility statistics at the national, divisional, state, company, and plant levels on the following subjects: quantity of fuel, cost of fuel, quality of fuel, net generation, fuel consumption, and fuel stocks. In addition, the EPQ presents a quarterly summary of reported major disturbances and unusual occurrences. These data are collected on the Form IE-417R. Every electric utility engaged in the generation, transmission, or distribution of electric energy must file a report with DOE if it experiences a major power system emergency.

Greenhouse gas impacts of natural gas: Influence of deployment choice, methane leak rate, and methane GWP

NASA Astrophysics Data System (ADS)

Cohan, D. S.

2015-12-01

Growing supplies of natural gas have heightened interest in the net impacts of natural gas on climate. Although its production and consumption result in greenhouse gas emissions, natural gas most often substitutes for other fossil fuels whose emission rates may be higher. Because natural gas can be used throughout the sectors of the energy economy, its net impacts on greenhouse gas emissions will depend not only on the leak rates of production and distribution, but also on the use for which natural gas is substituted. Here, we present our estimates of the net greenhouse gas emissions impacts of substituting natural gas for other fossil fuels for five purposes: light-duty vehicles, transit buses, residential heating, electricity generation, and export for electricity generation overseas. Emissions are evaluated on a fuel cycle basis, from production and transport of each fuel through end use combustion, based on recent conditions in the United States. We show that displacement of existing coal-fired electricity and heating oil furnaces yield the largest reductions in emissions. The impact of compressed natural gas replacing petroleum-based vehicles is highly uncertain, with the sign of impact depending on multiple assumptions. Export of liquefied natural gas for electricity yields a moderate amount of emissions reductions. We further show how uncertainties in upstream emission rates for natural gas and in the global warming potential of methane influence the net greenhouse gas impacts. Our presentation will make the case that how natural gas is deployed is crucial to determining how it will impact climate.

Long-term economic benefits attributed to IVF-conceived children: a lifetime tax calculation.

PubMed

Connolly, Mark P; Pollard, Michael S; Hoorens, Stijn; Kaplan, Brian R; Oskowitz, Selwyn P; Silber, Sherman J

2008-09-01

To evaluate whether lifetime future net tax revenues from an in vitro fertilization (IVF)-conceived child are substantial enough to warrant public subsidy relative to the mean IVF treatment costs required to obtain 1 live birth. Mathematical generational accounting model. The model estimates direct financial interactions between the IVF-conceived child and the government during the child's projected lifetime. In the model, we accrue IVF costs required to conceive the child to the government, and then we estimate future net tax revenue to the federal and state governments from this individual, offset by direct financial transfers from the government (eg, child allowances, education, Medicare, and Social Security). We discount lifetime costs and gross tax payments at Treasury Department rates to establish the present value of investing in IVF. We applied US Congressional Budget Office projected changes in tax rates over the course of the model. An IVF-conceived child, average in every respect (eg, future earnings, healthcare consumption, and life expectancy), represents a net positive return to the government. Based on an average employed individual born in 2005, the projected net lifetime tax contribution is US $606,200. Taking into consideration IVF costs and all direct financial interactions, the net present value is US $155,870. Lifetime net taxes paid from a child relative to the child's initial IVF investment represent a 700% net return to the government in discounted US dollars from fully employed individuals. This suggests that removing barriers to IVF would have positive tax benefits for the government, notwithstanding its beneficial effect on overall economic growth.

Army Net Zero Prove Out. Net Zero Energy Best Practices

DTIC Science & Technology

2014-11-18

energy which is then used to drive a heat engine to generate electrical power. Geothermal Power – These systems use thermal energy generated and...stored in the earth as a generating source for electricity. Several pilot installations are investigating this technology by conducting geothermal ...concentrate solar thermal energy which is then used to drive a heat engine to generate electrical power. • Geothermal Power - These systems use thermal energy

Ohio | Midmarket Solar Policies in the United States | Solar Research |

Science.gov Websites

Meter aggregation: Virtual net metering is allowed for state, municipal, and agricultural customers state, municipal, or agricultural host under certain conditions. Net excess generation from virtual net

Net Venn - An integrated network analysis web platform for gene lists

USDA-ARS?s Scientific Manuscript database

Many lists containing biological identifiers such as gene lists have been generated in various genomics projects. Identifying the overlap among gene lists can enable us to understand the similarities and differences between the datasets. Here, we present an interactome network-based web application...

Understanding the effects of decompaction maintenance on the infill state and play performance of third-generation artificial grass pitches

PubMed Central

Forrester, Stephanie E; McLaren, Nicholas J

2015-01-01

Third generation artificial grass pitches have been observed to get harder over time. The maintenance technique of rubber infill decompaction is intended to help slow, or reverse, this process. At present, little is understood about either the science of the infill compaction process or the efficacy of decompaction maintenance. The objective of this study was to measure the changes in rubber infill net bulk density, force reduction (impact absorption) and vertical ball rebound under various levels of compactive effort in controlled laboratory-based testing. The assessments were repeated after the systems had been raked to simulate the decompaction maintenance techniques. These tests defined the limits of compaction (loose to maximally compacted) in terms of the change in rubber infill net bulk density, force reduction and vertical ball rebound. Site testing was also undertaken at four third generation pitches immediately pre and post decompaction, to determine the measurable effects in the less well controlled field environment. Rubber infill net bulk density was found to increase as compactive effort increased, resulting in increased hardness. Decompacting the surface was found to approximately fully reverse these effects. In comparison, the site measurements demonstrated similar but notably smaller magnitudes of change following the decompaction process suggesting that the field state pre and post decompaction did not reach the extremes obtained in the laboratory. The findings suggest that rubber infill net bulk density is an important parameter influencing the hardness of artificial grass and that decompactions can be an effective method to reverse compaction related hardness changes. PMID:29708108

47 CFR 32.7210 - Operating investment tax credits-net.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Operating investment tax credits-net. 32.7210....7210 Operating investment tax credits—net. (a) This account shall be charged and Account 4320, Unamortized Operating Investment Tax Credits—Net, shall be credited with investment tax credits generated from...

Effects of normoxic and hypoxic exercise regimens on monocyte-mediated thrombin generation in sedentary men.

PubMed

Wang, Jong-Shyan; Chang, Ya-Lun; Chen, Yi-Ching; Tsai, Hsing-Hua; Fu, Tieh-Cheng

2015-08-01

Exercise and hypoxia paradoxically modulate vascular thrombotic risks. The shedding of procoagulant-rich microparticles from monocytes may accelerate the pathogenesis of atherothrombosis. The present study explores the manner in which normoxic and hypoxic exercise regimens affect procoagulant monocyte-derived microparticle (MDMP) formation and monocyte-promoted thrombin generation (TG). Forty sedentary healthy males were randomized to perform either normoxic (NET; 21% O2, n=20) or hypoxic (HET; 15% O2, n=20) exercise training (60% VO(2max)) for 30 min/day, 5 days/week for 5 weeks. At rest and immediately after HET (100 W under 12% O2 for 30 min), the MDMP characteristics and dynamic TG were measured by flow cytometry and thrombinography respectively. The results demonstrated that acute 12% O2 exercise (i) increased the release of coagulant factor V (FV)/FVIII-rich, phosphatidylserine (PS)-exposed and tissue factor (TF)-expressed microparticles from monocytes, (ii) enhanced the peak height and rate of TG in monocyte-rich plasma (MRP) and (iii) elevated concentrations of norepinephrine/epinephrine, myeloperoxidase (MPO) and interleukin-6 (IL-6) in plasma. Following the 5-week intervention, HET exhibited higher enhancements of peak work-rate and cardiopulmonary fitness than NET did. Moreover, both NET and HET decreased the FV/FVIII-rich, PS-exposed and TF-expressed MDMP counts and the peak height and rate of TG in MRP following the HET. However, HET elicited more suppression for the HE (hypoxic exercise)-enhanced procoagulant MDMP formation and dynamic TG in MPR and catecholamine/peroxide/pro-inflammatory cytokine levels in plasma than NET. Hence, we conclude that HET is superior to NET for enhancing aerobic capacity. Furthermore, HET effectively suppresses procoagulant MDMP formation and monocyte-mediated TG under severe hypoxic stress, compared with NET.

Prediction of AMD generation potential in mining waste piles, in the Sarcheshmeh porphyry copper deposit, Iran.

PubMed

Modabberi, Soroush; Alizadegan, Ali; Mirnejad, Hassan; Esmaeilzadeh, Esmat

2013-11-01

This study investigates the possibility of acid mine drainage (AMD) generation in active and derelict mine waste piles in Sarcheshmeh Copper Mine produced in several decades, using static tests including acid-base accounting (ABA) and net acid-generating pH (NAGpH). In this study, 51 composite samples were taken from 11 waste heaps, and static ABA and NAGpH tests were carried out on samples. While some piles are acid producing at present and AMD is discharging from the piles, most of them do not show any indication on their AMD potential, and they were investigated to define their acid-producing potential. The analysis of data indicates that eight waste piles are potentially acid generating with net neutralization potentials (NNPs) of -56.18 to -199.3, net acid generating of 2.19-3.31, and NPRs from 0.18 to 0.44. Other waste piles exhibited either a very low sulfur, high carbonate content or excess carbonate over sulfur; hence, they are not capable of acid production or they can be considered as weak acid producers. Consistency between results of ABA and NAGpH tests using a variety of classification criteria validates these tests as powerful means for preliminary evaluation of AMD/ARD possibilities in any mining district. It is also concluded that some of the piles with very negative NNPs are capable to produce AMD naturally, and they can be used in heap leaching process for economic recovery of trace amounts of metals without applying any biostimulation methods.

Preparing for Change in the Federal Information Technology Workforce

DTIC Science & Technology

2008-01-01

Boom Generation, born 1946 to 1964; Generation X (or Gen X), born 1965 to 1977; and the Net Generation (also called Generation Y or the Millennials ...Management and others, the future workforce can be characterized as: • More diverse, as measured by ethnicity, age, race, religion , family background...they cannot get a seat at the table to get their views heard. Baby Millennials or Greatest Generation Boomers Gen-X Net-Gen Age 64–84 45–63 32–44 19

The Key to Competitiveness: Understanding the Next Generation Learner--A Guide for College and University Leaders

ERIC Educational Resources Information Center

American Association of State Colleges and Universities, 2004

2004-01-01

It is unclear whether the Net generation is pushing innovations in communications technologies (because of their fascination with it) or if advances in communications technologies are influencing the Net generation. That discussion is not nearly as relevant as their perceptions of the role technology plays in their lives. Whereas the older peers…

Angular Impulse and Balance Regulation During the Golf Swing.

PubMed

Peterson, Travis J; Wilcox, Rand R; McNitt-Gray, Jill L

2016-08-01

Our aim was to determine how skilled players regulate linear and angular impulse while maintaining balance during the golf swing. Eleven highly-skilled golf players performed swings with a 6-iron and driver. Components contributing to linear and angular impulse generated by the rear and target legs (resultant horizontal reaction force [RFh], RFh-angle, and moment arm) were quantified and compared across the group and within a player (α = .05). Net angular impulse generated by both the rear and target legs was greater for the driver than the 6-iron. Mechanisms used to regulate angular impulse generation between clubs varied across players and required coordination between the legs. Increases in net angular impulse with a driver involved increases in target leg RFh. Rear leg RFh-angle was maintained between clubs whereas target leg RFh became more aligned with the target line. Net linear impulse perpendicular to the target line remained near zero, preserving balance, while net linear impulse along the target line decreased in magnitude. These results indicate that the net angular impulse was regulated between clubs by coordinating force generation of the rear and target legs while sustaining balance throughout the task.

Performance optimization of an MHD generator with physical constraints

NASA Technical Reports Server (NTRS)

Pian, C. C. P.; Seikel, G. R.; Smith, J. M.

1979-01-01

A technique has been described which optimizes the power out of a Faraday MHD generator operating under a prescribed set of electrical and magnetic constraints. The method does not rely on complicated numerical optimization techniques. Instead the magnetic field and the electrical loading are adjusted at each streamwise location such that the resultant generator design operates at the most limiting of the cited stress levels. The simplicity of the procedure makes it ideal for optimizing generator designs for system analysis studies of power plants. The resultant locally optimum channel designs are, however, not necessarily the global optimum designs. The results of generator performance calculations are presented for an approximately 2000 MWe size plant. The difference between the maximum power generator design and the optimal design which maximizes net MHD power are described. The sensitivity of the generator performance to the various operational parameters are also presented.

Analysis of the net energy use impacts of PURPA (Public Utility Regulatory Policy Act) electricity generation under alternative assumptions regarding the technology mix of PURPA generators and displaced utility generators: Final report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

The goals of this study were to explore the magnitude of potential fuel savings (or increased fuel consumption) under different possible combinations of Qualifying Facilities generation and utility displacement, and to identify those combinations which might result in a net increase in fuel consumption. In exploring the impact of cogeneration net heat rate on net savings (or increase) in fuel consumption, the study also addressed the extent to which cogenerator efficiency affects the overall fuel use impact of Public Utility Regulatory Policies Act (PURPA) implementation. This research thus seeks to identify possible scenarios in which PURPA implementation may not resultmore » in the conversation of fossil fuels, and to define possible situations in which the FERC's efficiency standard may lead to energy-inefficient Qualifying Facility development. 9 refs., 6 figs., 6 tabs.« less

State Electricity Profiles

EIA Publications

2017-01-01

The annual report presents data tables describing the electricity industry in each State. Data include: summary statistics; the 10 largest plants by generating capacity; the top five entities ranked by sector; electric power industry generating capacity by primary energy source; electric power industry generation by primary energy source; utility delivered fuel prices for coal, petroleum, and natural gas; electric power industry emissions estimates; retail sales, revenue, and average retail price by sector; retail electricity sales statistics; and supply and disposition of electricity; net metering counts and capacity by technology and customer type; and advanced metering counts by customer type.

The Impact of Rate Design and Net Metering on the Bill Savings from Distributed PV for Residential Customers in California

DOE Office of Scientific and Technical Information (OSTI.GOV)

Energy and Resources Group, University of California, Berkeley; Darghouth, Naim R.; Barbose, Galen

2011-06-01

Net metering has become a widespread mechanism in the U.S. for supporting customer adoption of distributed photovoltaics (PV), but has faced challenges as PV installations grow to a larger share of generation in a number of states. This paper examines the value of the bill savings that customers receive under net metering, and the associated role of retail rate design, based on a sample of approximately two hundred residential customers of California's two largest electric utilities. We find that the bill savings per kWh of PV electricity generated varies by more than a factor of four across the customers inmore » the sample, which is largely attributable to the inclining block structure of the utilities' residential retail rates. We also compare the bill savings under net metering to that received under three potential alternative compensation mechanisms, based on California's Market Price Referent (MPR). We find that net metering provides significantly greater bill savings than a full MPR-based feed-in tariff, but only modestly greater savings than alternative mechanisms under which hourly or monthly net excess generation is compensated at the MPR rate.« less

Loss of Chromosome 18 in Neuroendocrine Tumors of the Small Intestine: The Enigma Remains.

PubMed

Nieser, Maike; Henopp, Tobias; Brix, Joachim; Stoß, Laura; Sitek, Barbara; Naboulsi, Wael; Anlauf, Martin; Schlitter, Anna M; Klöppel, Günter; Gress, Thomas; Moll, Roland; Bartsch, Detlef K; Heverhagen, Anna E; Knoefel, Wolfram T; Kaemmerer, Daniel; Haybaeck, Johannes; Fend, Falko; Sperveslage, Jan; Sipos, Bence

2017-01-01

Neuroendocrine tumors of the small intestine (SI-NETs) exhibit an increasing incidence and high mortality rate. Until now, no fundamental molecular event has been linked to the tumorigenesis and progression of these tumors. Only the loss of chromosome 18 (Chr18) has been shown in up to two thirds of SI-NETs, whereby the significance of this alteration is still not understood. We therefore performed the first comprehensive study to identify Chr18-related events at the genetic, epigenetic and gene/protein expression levels. We did expression analysis of all seven putative Chr18-related tumor suppressors by quantitative real-time PCR (qRT-PCR), Western blot and immunohistochemistry. Next-generation exome sequencing and SNP array analysis were performed with five SI-NETs with (partial) loss of Chr18. Finally, we analyzed all microRNAs (miRNAs) located on Chr18 by qRT-PCR, comparing Chr18+/- and Chr18+/+ SI-NETs. Only DCC (deleted in colorectal cancer) revealed loss of/greatly reduced expression in 6/21 cases (29%). No relevant loss of SMAD2, SMAD4, elongin A3 and CABLES was detected. PMAIP1 and maspin were absent at the protein level. Next-generation sequencing did not reveal relevant recurrent somatic mutations on Chr18 either in an exploratory cohort of five SI-NETs, or in a validation cohort (n = 30). SNP array analysis showed no additional losses. The quantitative analysis of all 27 Chr18-related miRNAs revealed no difference in expression between Chr18+/- and Chr18+/+ SI-NETs. DCC seems to be the only Chr18-related tumor suppressor affected by the monoallelic loss of Chr18 resulting in a loss of DCC protein expression in one third of SI-NETs. No additional genetic or epigenetic alterations were present on Chr18. © 2016 S. Karger AG, Basel.

Animal emotions, behaviour and the promotion of positive welfare states.

PubMed

Mellor, D J

2012-01-01

This paper presents a rationale that may significantly boost the drive to promote positive welfare states in animals. The rationale is based largely, but not exclusively, on an experimentally supported neuropsychological understanding of relationships between emotions and behaviour, an understanding that has not yet been incorporated into animal welfare science thinking. Reference is made to major elements of the neural/cognitive foundations of motivational drives that energise and direct particular behaviours and their related subjective or emotional experiences. These experiences are generated in part by sensory inputs that reflect the animal's internal functional state and by neural processing linked to the animal's perception of its external circumstances. The integrated subjective or emotional outcome of these inputs corresponds to the animal's welfare status. The internally generated subjective experiences represent motivational urges or drives that are predominantly negative and include breathlessness, thirst, hunger and pain. They are generated by, and elicit specific behaviours designed to correct, imbalances in the animal's internal functional state. Externally generated subjective experiences are said to be integral to the operation of interacting 'action-orientated systems' that give rise to particular behaviours and their negative or positive emotional contents. These action-orientated systems, described in neuropsychological terms, give rise to negative emotions that include fear, anger and panic, and positive emotions that include comfort, vitality, euphoria and playfulness. It is argued that early thinking about animal welfare management focused mainly on minimising disturbances to the internal functional states that generate associated unpleasant motivational urges or drives. This strategy produced animal welfare benefits, but at best it could only lift a poor net welfare status to a neutral one. In contrast, strategies designed to manipulate the emotional action-orientated systems have the potential to replace the negative emotions generated within those systems with positive ones, and thereby may lift a poor net state of welfare beyond the neutral point to a net positive state. It is hoped that the analysis presented here will enhance the drive to promote positive welfare states by providing cogent and convincing neuropsychological support for the formulation of additional, more directed welfare code recommendations and standards that focus on the animal's behaviour.

A 3D Active Learning Application for NeMO-Net, the NASA Neural Multi-Modal Observation and Training Network for Global Coral Reef Assessment

NASA Technical Reports Server (NTRS)

van den Bergh, Jarrett; Schutz, Joey; Li, Alan; Chirayath, Ved

2017-01-01

NeMO-Net, the NASA neural multi-modal observation and training network for global coral reef assessment, is an open-source deep convolutional neural network and interactive active learning training software aiming to accurately assess the present and past dynamics of coral reef ecosystems through determination of percent living cover and morphology as well as mapping of spatial distribution. We present an interactive video game prototype for tablet and mobile devices where users interactively label morphology classifications over mm-scale 3D coral reef imagery captured using fluid lensing to create a dataset that will be used to train NeMO-Nets convolutional neural network. The application currently allows for users to classify preselected regions of coral in the Pacific and will be expanded to include additional regions captured using our NASA FluidCam instrument, presently the highest-resolution remote sensing benthic imaging technology capable of removing ocean wave distortion, as well as lower-resolution airborne remote sensing data from the ongoing NASA CORAL campaign. Active learning applications present a novel methodology for efficiently training large-scale Neural Networks wherein variances in identification can be rapidly mitigated against control data. NeMO-Net periodically checks users input against pre-classified coral imagery to gauge their accuracy and utilize in-game mechanics to provide classification training. Users actively communicate with a server and are requested to classify areas of coral for which other users had conflicting classifications and contribute their input to a larger database for ranking. In partnering with Mission Blue and IUCN, NeMO-Net leverages an international consortium of subject matter experts to classify areas of confusion identified by NeMO-Net and generate additional labels crucial for identifying decision boundary locations in coral reef assessment.

A 3D Active Learning Application for NeMO-Net, the NASA Neural Multi-Modal Observation and Training Network for Global Coral Reef Assessment

NASA Astrophysics Data System (ADS)

van den Bergh, J.; Schutz, J.; Chirayath, V.; Li, A.

2017-12-01

NeMO-Net, the NASA neural multi-modal observation and training network for global coral reef assessment, is an open-source deep convolutional neural network and interactive active learning training software aiming to accurately assess the present and past dynamics of coral reef ecosystems through determination of percent living cover and morphology as well as mapping of spatial distribution. We present an interactive video game prototype for tablet and mobile devices where users interactively label morphology classifications over mm-scale 3D coral reef imagery captured using fluid lensing to create a dataset that will be used to train NeMO-Net's convolutional neural network. The application currently allows for users to classify preselected regions of coral in the Pacific and will be expanded to include additional regions captured using our NASA FluidCam instrument, presently the highest-resolution remote sensing benthic imaging technology capable of removing ocean wave distortion, as well as lower-resolution airborne remote sensing data from the ongoing NASA CORAL campaign.Active learning applications present a novel methodology for efficiently training large-scale Neural Networks wherein variances in identification can be rapidly mitigated against control data. NeMO-Net periodically checks users' input against pre-classified coral imagery to gauge their accuracy and utilizes in-game mechanics to provide classification training. Users actively communicate with a server and are requested to classify areas of coral for which other users had conflicting classifications and contribute their input to a larger database for ranking. In partnering with Mission Blue and IUCN, NeMO-Net leverages an international consortium of subject matter experts to classify areas of confusion identified by NeMO-Net and generate additional labels crucial for identifying decision boundary locations in coral reef assessment.

Second Language Teaching and Learning in the Net Generation

ERIC Educational Resources Information Center

Oxford, Raquel, Ed.; Oxford, Jeffrey, Ed.

2009-01-01

Today's young people--the Net Generation--have grown up with technology all around them. However, teachers cannot assume that students' familiarity with technology in general transfers successfully to pedagogical settings. This volume examines various technologies and offers concrete advice on how each can be successfully implemented in the second…

Economic value of in vitro fertilization in Ukraine, Belarus, and Kazakhstan.

PubMed

Mandrik, Olena; Knies, Saskia; Severens, Johan L

2015-01-01

An economic value calculation was performed to estimate the lifetime net present value of in vitro fertilization (IVF) in Ukraine, Belarus, and Kazakhstan. Net lifetime tax revenues were used to represent governmental benefits accruing from a hypothetical cohort of an IVF population born in 2009 using the methodology of generational accounting. Governmental expenses related to this population included social benefits, education and health care, unemployment support, and pensions. Where available, country-specific data referencing official sources were applied. The average health care cost needed to achieve one additional birth from the governmental perspective varied from $2,599 in Ukraine to $5,509 in Belarus. The net present value from the population born using IVF was positive in all countries: for Ukraine ($9,839), Belarus ($21,702), and Kazakhstan ($2,295). The break-even costs of drugs and supplies per IVF procedure is expected to be $3,870, $8,530, and $1,780, respectively. Probabilistic sensitivity analyses based on 5,000 simulations show that the average net present value per person remains positive: $1,894±$7,619, $27,925±$12,407, and $17,229±$24,637 in Ukraine, Belarus, and Kazakhstan, respectively. Financing IVF may represent a good investment in terms of governmental financial returns, even in lower-income countries with state-financed health care systems such as Ukraine, Belarus, and Kazakhstan.

Economic value of in vitro fertilization in Ukraine, Belarus, and Kazakhstan

PubMed Central

Mandrik, Olena; Knies, Saskia; Severens, Johan L

2015-01-01

Background An economic value calculation was performed to estimate the lifetime net present value of in vitro fertilization (IVF) in Ukraine, Belarus, and Kazakhstan. Methods Net lifetime tax revenues were used to represent governmental benefits accruing from a hypothetical cohort of an IVF population born in 2009 using the methodology of generational accounting. Governmental expenses related to this population included social benefits, education and health care, unemployment support, and pensions. Where available, country-specific data referencing official sources were applied. Results The average health care cost needed to achieve one additional birth from the governmental perspective varied from $2,599 in Ukraine to $5,509 in Belarus. The net present value from the population born using IVF was positive in all countries: for Ukraine ($9,839), Belarus ($21,702), and Kazakhstan ($2,295). The break-even costs of drugs and supplies per IVF procedure is expected to be $3,870, $8,530, and $1,780, respectively. Probabilistic sensitivity analyses based on 5,000 simulations show that the average net present value per person remains positive: $1,894±$7,619, $27,925±$12,407, and $17,229±$24,637 in Ukraine, Belarus, and Kazakhstan, respectively. Conclusion Financing IVF may represent a good investment in terms of governmental financial returns, even in lower-income countries with state-financed health care systems such as Ukraine, Belarus, and Kazakhstan. PMID:26109873

Net Rotation of the Lithosphere in Mantle Convection Models with Self-consistent Plate Generation

NASA Astrophysics Data System (ADS)

Gerault, M.; Coltice, N.

2017-12-01

Lateral variations in the viscosity structure of the lithosphere and the mantle give rise to a discordant motion between the two. In a deep mantle reference frame, this motion is called the net rotation of the lithosphere. Plate motion reconstructions, mantle flow computations, and inferences from seismic anisotropy all indicate some amount of net rotation using different mantle reference frames. While the direction of rotation is somewhat consistent across studies, the predicted amplitudes range from 0.1 deg/Myr to 0.3 deg/Myr at the present-day. How net rotation rates could have differed in the past is also a subject of debate and strong geodynamic arguments are missing from the discussion. This study provides the first net rotation calculations in 3-D spherical mantle convection models with self-consistent plate generation. We run the computations for billions of years of numerical integration. We look into how sensitive the net rotation is to major tectonic events, such as subduction initiation, continental breakup and plate reorganisations, and whether some governing principles from the models could guide plate motion reconstructions. The mantle convection problem is solved with the finite volume code StagYY using a visco-pseudo-plastic rheology. Mantle flow velocities are solely driven by buoyancy forces internal to the system, with free slip upper and lower boundary conditions. We investigate how the yield stress, the mantle viscosity structure and the properties of continents affect the net rotation over time. Models with large lateral viscosity variations from continents predict net rotations that are at least threefold faster than those without continents. Models where continents cover a third of the surface produce net rotation rates that vary from nearly zero to over 0.3 deg/Myr with rapide increase during continental breakup. The pole of rotation appears to migrate along no particular path. For all models, regardless of the yield stress and the presence of continental material, the most substantial variations in amplitude and direction of rotation occur over a few tenth of millions of years. It suggests that, to first order, the net rotation is closely related to the tectonic make-up of the surface, evolving with the nature of plate boundaries and the physical arrangement of the plates.

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

The Coal and Electric Data and Renewables Division; Office of Coal, Nuclear, Electric and Alternate Fuels, Energy Information Administration (EIA), Department of Energy prepares the EPM. This publication provides monthly statistics at the State, Census division, and U.S. levels for net generation, fossil fuel consumption and stocks, quantity and quality of fossil fuels, cost of fossil fuels, electricity retail sales, associated revenue, and average revenue per kilowatthour of electricity sold. In addition, data on net generation, fuel consumption, fuel stocks, quantity and cost of fossil fuels are also displayed for the North American Electric Reliability Council (NERC) regions. The EIAmore » publishes statistics in the EPM on net generation by energy source; consumption, stocks, quantity, quality, and cost of fossil fuels; and capability of new generating units by company and plant.« less

Time value of emission and technology discounting rate for off-grid electricity generation in India using intermediate pyrolysis

DOE Office of Scientific and Technical Information (OSTI.GOV)

Patel, Amit, E-mail: amitrp@iitrpr.ac.in; Faculty of Technology and Engineering, The Maharaja Sayajirao University of Baroda, Vadodara 390001, Gujarat; Sarkar, Prabir

The environmental impact assessment of a process over its entire operational lifespan is an important issue. Estimation of life cycle emission helps in predicting the contribution of a given process to abate (or to pollute) the environmental emission scenario. Considering diminishing and time-dependent effect of emission, assessment of the overall effect of emissions is very complex. The paper presents a generalized methodology for arriving at a single emission discounting number for a process option, using the concept of time value of carbon emission flow. This number incorporates the effect of the emission resulting from the process over the entire operationalmore » lifespan. The advantage of this method is its quantitative aspect as well as its flexible nature. It can be applied to any process. The method is demonstrated with the help of an Intermediate Pyrolysis process when used to generate off-grid electricity and opting biochar route for disposing straw residue. The scenarios of very high net emission to very high net carbon sequestration is generated using process by careful selection of process parameters for different scenarios. For these different scenarios, the process discounting rate was determined and its outcome is discussed. The paper also proposes a process specific eco-label that mentions the discounting rates. - Highlight: • Methodology to obtain emission discounting rate for a process is proposed. • The method includes all components of life cycle emission converts into a time dependent discounting number. • A case study of Intermediate Pyrolysis is used to obtain such number for a range of processes. • The method is useful to determine if the effect from the operation of a process will lead to a net absorption of emission or net accumulation of emission in the environment.« less

Segmenting the Net-Generation: Embracing the Next Level of Technology

ERIC Educational Resources Information Center

Smith, Russell K.

2014-01-01

A segmentation study is used to partition college students into groups that are more or less likely to adopt tablet technology as a learning tool. Because the college population chosen for study presently relies upon laptop computers as their primary learning device, tablet technology represents a "next step" in technology. Student…

Optimization and life-cycle cost of health clinic PV system for a rural area in southern Iraq using HOMER software

DOE Office of Scientific and Technical Information (OSTI.GOV)

Al-Karaghouli, Ali; Kazmerski, L.L.

2010-04-15

This paper addresses the need for electricity of rural areas in southern Iraq and proposes a photovoltaic (PV) solar system to power a health clinic in that region. The total daily health clinic load is 31.6 kW h and detailed loads are listed. The National Renewable Energy Laboratory (NREL) optimization computer model for distributed power, ''HOMER,'' is used to estimate the system size and its life-cycle cost. The analysis shows that the optimal system's initial cost, net present cost, and electricity cost is US$ 50,700, US$ 60,375, and US$ 0.238/kW h, respectively. These values for the PV system are comparedmore » with those of a generator alone used to supply the load. We found that the initial cost, net present cost of the generator system, and electricity cost are US$ 4500, US$ 352,303, and US$ 1.332/kW h, respectively. We conclude that using the PV system is justified on humanitarian, technical, and economic grounds. (author)« less

Molecular wires acting as quantum heat ratchets.

PubMed

Zhan, Fei; Li, Nianbei; Kohler, Sigmund; Hänggi, Peter

2009-12-01

We explore heat transfer in molecular junctions between two leads in the absence of a finite net thermal bias. The application of an unbiased time-periodic temperature modulation of the leads entails a dynamical breaking of reflection symmetry, such that a directed heat current may emerge (ratchet effect). In particular, we consider two cases of adiabatically slow driving, namely, (i) periodic temperature modulation of only one lead and (ii) temperature modulation of both leads with an ac driving that contains a second harmonic, thus, generating harmonic mixing. Both scenarios yield sizable directed heat currents, which should be detectable with present techniques. Adding a static thermal bias allows one to compute the heat current-thermal load characteristics, which includes the ratchet effect of negative thermal bias with positive-valued heat flow against the thermal bias, up to the thermal stop load. The ratchet heat flow in turn generates also an electric current. An applied electric stop voltage, yielding effective zero electric current flow, then mimics a solely heat-ratchet-induced thermopower ("ratchet Seebeck effect"), although no net thermal bias is acting. Moreover, we find that the relative phase between the two harmonics in scenario (ii) enables steering the net heat current into a direction of choice.

Inertial attitude control of a bat-like morphing-wing air vehicle.

PubMed

Colorado, J; Barrientos, A; Rossi, C; Parra, C

2013-03-01

This paper presents a novel bat-like unmanned aerial vehicle inspired by the morphing-wing mechanism of bats. The goal of this paper is twofold. Firstly, a modelling framework is introduced for analysing how the robot should manoeuvre by means of changing wing morphology. This allows the definition of requirements for achieving forward and turning flight according to the kinematics of the wing modulation. Secondly, an attitude controller named backstepping+DAF is proposed. Motivated by biological evidence about the influence of wing inertia on the production of body accelerations, the attitude control law incorporates wing inertia information to produce desired roll (ϕ) and pitch (θ) acceleration commands (desired angular acceleration function (DAF)). This novel control approach is aimed at incrementing net body forces (F(net)) that generate propulsion. Simulations and wind-tunnel experimental results have shown an increase of about 23% in net body force production during the wingbeat cycle when the wings are modulated using the DAF as a part of the backstepping control law. Results also confirm accurate attitude tracking in spite of high external disturbances generated by aerodynamic loads at airspeeds up to 5 ms⁻¹.

Status of Net Metering: Assessing the Potential to Reach Program Caps

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heeter, J.; Gelman, R.; Bird, L.

2014-09-01

Several states are addressing the issue of net metering program caps, which limit the total amount of net metered generating capacity that can be installed in a state or utility service territory. In this analysis, we examine net metering caps to gain perspective on how long net metering will be available in various jurisdictions under current policies. We also surveyed state practices and experience to understand important policy design considerations.

WegenerNet climate station network region Feldbach/Austria: From local measurements to weather and climate data products at 1 km-scale resolution

NASA Astrophysics Data System (ADS)

Kabas, T.; Leuprecht, A.; Bichler, C.; Kirchengast, G.

2010-12-01

South-eastern Austria is characteristic for experiencing a rich variety of weather and climate patterns. For this reason, the county of Feldbach was selected by the Wegener Center as a focus area for a pioneering observation experiment at very high resolution: The WegenerNet climate station network (in brief WegenerNet) comprises 151 meteorological stations within an area of about 20 km × 15 km (~ 1.4 km × 1.4 km station grid). All stations measure the main parameters temperature, humidity and precipitation with 5 minute sampling. Selected further stations include measurements of wind speed and direction completed by soil parameters as well as air pressure and net radiation. The collected data is integrated in an automatic processing system including data transfer, quality control, product generation, and visualization. Each station is equipped with an internet-attached data logger and the measurements are transferred as binary files via GPRS to the WegenerNet server in 1 hour intervals. The incoming raw data files of measured parameters as well as several operating values of the data logger are stored in a relational database (PostgreSQL). Next, the raw data pass the Quality Control System (QCS) in which the data are checked for its technical and physical plausibility (e.g., sensor specifications, temporal and spatial variability). In consideration of the data quality (quality flag), the Data Product Generator (DPG) results in weather and climate data products on various temporal scales (from 5 min to annual) for single stations and regular grids. Gridded data are derived by vertical scaling and squared inverse distance interpolation (1 km × 1 km and 0.01° × 0.01° grids). Both subsystems (QCS and DPG) are realized by the programming language Python. For application purposes the resulting data products are available via the bi-lingual (dt, en) WegenerNet data portal (www.wegenernet.org). At this time, the main interface is still online in a system in which MapServer is used to import spatial data by its database interface and to generate images of static geographic formats. However, a Java applet is additionally needed to display these images on the users local host. Furthermore, station data are visualized as time series by the scripting language PHP. Since February 2010, the visualization of gridded data products is a first step to a new data portal based on OpenLayers. In this GIS framework, all geographic information (e.g., OpenStreetMap) is displayed with MapServer. Furthermore, the visualization of all meteorological parameters are generated on the fly by a Python CGI script and transparently overlayed on the maps. Hence, station data and gridded data are visualized and further prepared for download in common data formats (csv, NetCDF). In conclusion, measured data and generated data products are provided with a data latency less than 1-2 hours in standard operation (near real time). Following an introduction of the processing system along the lines above, resulting data products are presented online at the WegenerNet data portal.

On INM's Use of Corrected Net Thrust for the Prediction of Jet Aircraft Noise

NASA Technical Reports Server (NTRS)

McAninch, Gerry L.; Shepherd, Kevin P.

2011-01-01

The Federal Aviation Administration s (FAA) Integrated Noise Model (INM) employs a prediction methodology that relies on corrected net thrust as the sole correlating parameter between aircraft and engine operating states and aircraft noise. Thus aircraft noise measured for one set of atmospheric and aircraft operating conditions is assumed to be applicable to all other conditions as long as the corrected net thrust remains constant. This hypothesis is investigated under two primary assumptions: (1) the sound field generated by the aircraft is dominated by jet noise, and (2) the sound field generated by the jet flow is adequately described by Lighthill s theory of noise generated by turbulence.

Exergy & economic analysis of biogas fueled solid oxide fuel cell systems

NASA Astrophysics Data System (ADS)

Siefert, Nicholas S.; Litster, Shawn

2014-12-01

We present an exergy and an economic analysis of a power plant that uses biogas produced from a thermophilic anaerobic digester (AD) to fuel a solid oxide fuel cell (SOFC). We performed a 4-variable parametric analysis of the AD-SOFC system in order to determine the optimal design operation conditions, depending on the objective function of interest. We present results on the exergy efficiency (%), power normalized capital cost ( kW-1), and the internal rate of return on investment, IRR, (% yr-1) as a function of the current density, the stack pressure, the fuel utilization, and the total air stoichiometric ratio. To the authors' knowledge, this is the first AD-SOFC paper to include the cost of the AD when conducting economic optimization of the AD-SOFC plant. Our calculations show that adding a new AD-SOFC system to an existing waste water treatment (WWT) plant could yield positives values of IRR at today's average electricity prices and could significantly out-compete other options for using biogas to generate electricity. AD-SOFC systems could likely convert WWT plants into net generators of electricity rather than net consumers of electricity while generating economically viable rates of return on investment if the costs of SOFC systems are within a factor of two of the DOE/SECA cost targets.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Heeter, J.; Bird, L.; Gelman, R.

Several states are addressing the issue of net metering program caps, which limit the total amount of net metered generating capacity that can be installed in a state or utility service territory. In this analysis, we examine net metering caps to gain perspective on how long net metering will be available in various jurisdictions under current policies. We also surveyed state practices and experience to understand important policy design considerations.

What College Instructors Can Do about Student Cyber-Slacking

ERIC Educational Resources Information Center

Flanigan, Abraham E.; Kiewra, Kenneth A.

2018-01-01

Today's traditional-aged college students are avid users of mobile technology. Commonly referred to as the Net Generation, today's college students spend several hours each day using their smart phones, iPads, and laptops. Although some scholars initially opined that the Net Generation would grow into technologically savvy digital natives who…

Googling Allusions: Teaching Eliot to the Net Generation

ERIC Educational Resources Information Center

Hoff, Ann K.

2009-01-01

For years, 20th century American poetry professor Ann Hoff resisted digital pedagogy. However, for students of the Net Generation electronic communication is their main mode of interaction with peers and often with their professors. Further, their instinct when seeking information, is to seek it online. They are not merely computer proficient and…

Generation of net sediment transport by velocity skewness in oscillatory sheet flow

NASA Astrophysics Data System (ADS)

Chen, Xin; Li, Yong; Chen, Genfa; Wang, Fujun; Tang, Xuelin

2018-01-01

This study utilizes a qualitative approach and a two-phase numerical model to investigate net sediment transport caused by velocity skewness beneath oscillatory sheet flow and current. The qualitative approach is derived based on the pseudo-laminar approximation of boundary layer velocity and exponential approximation of concentration. The two-phase model can obtain well the instantaneous erosion depth, sediment flux, boundary layer thickness, and sediment transport rate. It can especially illustrate the difference between positive and negative flow stages caused by velocity skewness, which is considerably important in determining the net boundary layer flow and sediment transport direction. The two-phase model also explains the effect of sediment diameter and phase-lag to sediment transport by comparing the instantaneous-type formulas to better illustrate velocity skewness effect. In previous studies about sheet flow transport in pure velocity-skewed flows, net sediment transport is only attributed to the phase-lag effect. In the present study with the qualitative approach and two-phase model, phase-lag effect is shown important but not sufficient for the net sediment transport beneath pure velocity-skewed flow and current, while the asymmetric wave boundary layer development between positive and negative flow stages also contributes to the sediment transport.

Studies in the extensively automatic construction of large odds-based inference networks from structured data. Examples from medical, bioinformatics, and health insurance claims data.

PubMed

Robson, B; Boray, S

2018-04-01

Theoretical and methodological principles are presented for the construction of very large inference nets for odds calculations, composed of hundreds or many thousands or more of elements, in this paper generated by structured data mining. It is argued that the usual small inference nets can sometimes represent rather simple, arbitrary estimates. Examples of applications in clinical and public health data analysis, medical claims data and detection of irregular entries, and bioinformatics data, are presented. Construction of large nets benefits from application of a theory of expected information for sparse data and the Dirac notation and algebra. The extent to which these are important here is briefly discussed. Purposes of the study include (a) exploration of the properties of large inference nets and a perturbation and tacit conditionality models, (b) using these to propose simpler models including one that a physician could use routinely, analogous to a "risk score", (c) examination of the merit of describing optimal performance in a single measure that combines accuracy, specificity, and sensitivity in place of a ROC curve, and (d) relationship to methods for detecting anomalous and potentially fraudulent data. Copyright © 2018 Elsevier Ltd. All rights reserved.

MitProNet: A Knowledgebase and Analysis Platform of Proteome, Interactome and Diseases for Mammalian Mitochondria

PubMed Central

Mao, Song; Chai, Xiaoqiang; Hu, Yuling; Hou, Xugang; Tang, Yiheng; Bi, Cheng; Li, Xiao

2014-01-01

Mitochondrion plays a central role in diverse biological processes in most eukaryotes, and its dysfunctions are critically involved in a large number of diseases and the aging process. A systematic identification of mitochondrial proteomes and characterization of functional linkages among mitochondrial proteins are fundamental in understanding the mechanisms underlying biological functions and human diseases associated with mitochondria. Here we present a database MitProNet which provides a comprehensive knowledgebase for mitochondrial proteome, interactome and human diseases. First an inventory of mammalian mitochondrial proteins was compiled by widely collecting proteomic datasets, and the proteins were classified by machine learning to achieve a high-confidence list of mitochondrial proteins. The current version of MitProNet covers 1124 high-confidence proteins, and the remainders were further classified as middle- or low-confidence. An organelle-specific network of functional linkages among mitochondrial proteins was then generated by integrating genomic features encoded by a wide range of datasets including genomic context, gene expression profiles, protein-protein interactions, functional similarity and metabolic pathways. The functional-linkage network should be a valuable resource for the study of biological functions of mitochondrial proteins and human mitochondrial diseases. Furthermore, we utilized the network to predict candidate genes for mitochondrial diseases using prioritization algorithms. All proteins, functional linkages and disease candidate genes in MitProNet were annotated according to the information collected from their original sources including GO, GEO, OMIM, KEGG, MIPS, HPRD and so on. MitProNet features a user-friendly graphic visualization interface to present functional analysis of linkage networks. As an up-to-date database and analysis platform, MitProNet should be particularly helpful in comprehensive studies of complicated biological mechanisms underlying mitochondrial functions and human mitochondrial diseases. MitProNet is freely accessible at http://bio.scu.edu.cn:8085/MitProNet. PMID:25347823

A distributed Petri Net controller for a dual arm testbed

NASA Technical Reports Server (NTRS)

Bjanes, Atle

1991-01-01

This thesis describes the design and functionality of a Distributed Petri Net Controller (DPNC). The controller runs under X Windows to provide a graphical interface. The DPNC allows users to distribute a Petri Net across several host computers linked together via a TCP/IP interface. A sub-net executes on each host, interacting with the other sub-nets by passing a token vector from host to host. One host has a command window which monitors and controls the distributed controller. The input to the DPNC is a net definition file generated by Great SPN. Thus, a net may be designed, analyzed and verified using this package before implementation. The net is distributed to the hosts by tagging transitions that are host-critical with the appropriate host number. The controller will then distribute the remaining places and transitions to the hosts by generating the local nets, the local marking vectors and the global marking vector. Each transition can have one or more preconditions which must be fulfilled before the transition can fire, as well as one or more post-processes to be executed after the transition fires. These implement the actual input/output to the environment (machines, signals, etc.). The DPNC may also be used to simulate a Great SPN net since stochastic and deterministic firing rates are implemented in the controller for timed transitions.

Application of artificial neural networks to the design optimization of aerospace structural components

NASA Technical Reports Server (NTRS)

Berke, Laszlo; Patnaik, Surya N.; Murthy, Pappu L. N.

1993-01-01

The application of artificial neural networks to capture structural design expertise is demonstrated. The principal advantage of a trained neural network is that it requires trivial computational effort to produce an acceptable new design. For the class of problems addressed, the development of a conventional expert system would be extremely difficult. In the present effort, a structural optimization code with multiple nonlinear programming algorithms and an artificial neural network code NETS were used. A set of optimum designs for a ring and two aircraft wings for static and dynamic constraints were generated by using the optimization codes. The optimum design data were processed to obtain input and output pairs, which were used to develop a trained artificial neural network with the code NETS. Optimum designs for new design conditions were predicted by using the trained network. Neural net prediction of optimum designs was found to be satisfactory for most of the output design parameters. However, results from the present study indicate that caution must be exercised to ensure that all design variables are within selected error bounds.

Optimum Design of Aerospace Structural Components Using Neural Networks

NASA Technical Reports Server (NTRS)

Berke, L.; Patnaik, S. N.; Murthy, P. L. N.

1993-01-01

The application of artificial neural networks to capture structural design expertise is demonstrated. The principal advantage of a trained neural network is that it requires a trivial computational effort to produce an acceptable new design. For the class of problems addressed, the development of a conventional expert system would be extremely difficult. In the present effort, a structural optimization code with multiple nonlinear programming algorithms and an artificial neural network code NETS were used. A set of optimum designs for a ring and two aircraft wings for static and dynamic constraints were generated using the optimization codes. The optimum design data were processed to obtain input and output pairs, which were used to develop a trained artificial neural network using the code NETS. Optimum designs for new design conditions were predicted using the trained network. Neural net prediction of optimum designs was found to be satisfactory for the majority of the output design parameters. However, results from the present study indicate that caution must be exercised to ensure that all design variables are within selected error bounds.

Scaling net ecosystem production and net biome production over a heterogeneous region in the Western United States

Treesearch

D.P. Turner; W.D. Ritts; B.E. Law; W.B. Cohen; Z. Yan; T. Hudiburg; J.L. Campbell; M. Duane

2007-01-01

Bottom-up scaling of net ecosystem production (NEP) and net biome production (NBP) was used to generate a carbon budget for a large heterogeneous region (the state of Oregon, 2.5x105 km2 ) in the Western United States. Landsat resolution (30 m) remote sensing provided the basis for mapping land cover and disturbance history...

A technique for global monitoring of net solar irradiance at the ocean surface. I - Model

NASA Technical Reports Server (NTRS)

Frouin, Robert; Chertock, Beth

1992-01-01

An accurate long-term (84-month) climatology of net surface solar irradiance over the global oceans from Nimbus-7 earth radiation budget (ERB) wide-field-of-view planetary-albedo data is generated via an algorithm based on radiative transfer theory. Net surface solar irradiance is computed as the difference between the top-of-atmosphere incident solar irradiance (known) and the sum of the solar irradiance reflected back to space by the earth-atmosphere system (observed) and the solar irradiance absorbed by atmospheric constituents (modeled). It is shown that the effects of clouds and clear-atmosphere constituents can be decoupled on a monthly time scale, which makes it possible to directly apply the algorithm with monthly averages of ERB planetary-albedo data. Compared theoretically with the algorithm of Gautier et al. (1980), the present algorithm yields higher solar irradiance values in clear and thin cloud conditions and lower values in thick cloud conditions.

Evaluating CMA equalization of SOQPSK-TG data for aeronautical telemetry

NASA Astrophysics Data System (ADS)

Cole-Rhodes, Arlene; KoneDossongui, Serge; Umuolo, Henry; Rice, Michael

2015-05-01

This paper presents the results of using a constant modulus algorithm (CMA) to recover shaped offset quadrature-phase shift keying (SOQPSK)-TG modulated data, which has been transmitted using the iNET data packet structure. This standard is defined and used for aeronautical telemetry. Based on the iNET-packet structure, the adaptive block processing CMA equalizer can be initialized using the minimum mean square error (MMSE) equalizer [3]. This CMA equalizer is being evaluated for use on iNET structured data, with initial tests being conducted on measured data which has been received in a controlled laboratory environment. Thus the CMA equalizer is applied at the receiver to data packets which have been experimentally generated in order to determine the feasibility of our equalization approach, and its performance is compared to that of the MMSE equalizer. Performance evaluation is based on computed bit error rate (BER) counts for these equalizers.

Little Experience with ICT: Are They Really the Net Generation Student-Teachers?

ERIC Educational Resources Information Center

So, Hyo-Jeong; Choi, Hyungshin; Lim, Wei Ying; Xiong, Yao

2012-01-01

The aim of this study is to investigate the complexity of past experiences with ICT, pedagogical beliefs, and attitude toward ICT in education that the Net Generation student teachers have about their intention to teach and learn with technology. This study has a particular focus on their lived experiences as school students where ICT related…

Kansas | Solar Research | NREL

Science.gov Websites

1.1 MW. Kansas allows up to 100 kW of solar PV projects to be net metered. Midmarket customer Kansas's RPS. The utility and the customer-generator may sell any associated Renewable Energy Certificates aggregation: Not addressed As an alternative to net metering, customer-generators of systems up to 200 kW may

The Knowledge Building Paradigm: A Model of Learning for Net Generation Students

ERIC Educational Resources Information Center

Philip, Donald

2005-01-01

In this article Donald Philip describes Knowledge Building, a pedagogy based on the way research organizations function. The global economy, Philip argues, is driving a shift from older, industrial models to the model of the business as a learning organization. The cognitive patterns of today's Net Generation students, formed by lifetime exposure…

An Expanded Study of Net Generation Perceptions on Privacy and Security on Social Networking Sites (SNS)

ERIC Educational Resources Information Center

Lawler, James P.; Molluzzo, John C.; Doshi, Vijal

2012-01-01

Social networking on the Internet continues to be a frequent avenue of communication, especially among Net Generation consumers, giving benefits both personal and professional. The benefits may be eventually hindered by issues in information gathering and sharing on social networking sites. This study evaluates the perceptions of students taking a…

Greening the Net Generation: Outdoor Adult Learning in the Digital Age

ERIC Educational Resources Information Center

Walter, Pierre

2013-01-01

Adult learning today takes place primarily within walled classrooms or in other indoor settings, and often in front of various types of digital screens. As adults have adopted the digital technologies and indoor lifestyle attributed to the so-called "Net Generation," we have become detached from contact with the natural world outdoors.…

Infantry Communication Data

DTIC Science & Technology

1968-01-01

which forms a conducting medium between the electrodes of a dry cell , storage cell , or electrolytic capacitor. ELECTROMAGNETIC FIELD - A mlagnetic...Dry cel batteries. (2) Vehicular batteries. (3) Hand generators. (4) Gas engine generators. (5) Wet cell batteries. 2-5. NETTING TWO RADIO SETS: To net...1600 meters Power output .. .. .. ..... ..... ..... 5watt Power source. .. .. .. ..... ...... ... dry cell battery flA-270/U Battery lift

Workshop: Promoting Sustainability Through Net Zero Strategies

EPA Science Inventory

In 2011, EPA’s Office of Research and Development (ORD) signed an MOU with the U.S. Army to support the Army’s Net Zero initiative. The 17 Net Zero pilot installations aim to produce as much energy as used; limit freshwater use and increase water reuse; and reduce the generation ...

Neural-net Processed Electronic Holography for Rotating Machines

NASA Technical Reports Server (NTRS)

Decker, Arthur J.

2003-01-01

This report presents the results of an R&D effort to apply neural-net processed electronic holography to NDE of rotors. Electronic holography was used to generate characteristic patterns or mode shapes of vibrating rotors and rotor components. Artificial neural networks were trained to identify damage-induced changes in the characteristic patterns. The development and optimization of a neural-net training method were the most significant contributions of this work, and the training method and its optimization are discussed in detail. A second positive result was the assembly and testing of a fiber-optic holocamera. A major disappointment was the inadequacy of the high-speed-holography hardware selected for this effort, but the use of scaled holograms to match the low effective resolution of an image intensifier was one interesting attempt to compensate. This report also discusses in some detail the physics and environmental requirements for rotor electronic holography. The major conclusions were that neural-net and electronic-holography inspections of stationary components in the laboratory and the field are quite practical and worthy of continuing development, but that electronic holography of moving rotors is still an expensive high-risk endeavor.

Status of the KM3NeT project

NASA Astrophysics Data System (ADS)

Margiotta, A.

2014-04-01

KM3NeT is a deep-sea research infrastructure being constructed in the Mediterranean Sea. It will be installed at three sites: KM3NeT-Fr, offshore Toulon, France, KM3NeT-It, offshore Portopalo di Capo Passero, Sicily (Italy) and KM3NeT-Gr, offshore Pylos, Peloponnese, Greece. It will host the next generation Cherenkov neutrino telescope and nodes for a deep sea multidisciplinary observatory, providing oceanographers, marine biologists, and geophysicists with real time measurements. The neutrino telescope will search for Galactic and extra-Galactic sources of neutrinos, complementing IceCube in its field of view. The detector will have a modular structure and consists of six building blocks, each including about one hundred Detection Units (DUs). Each DU will be equipped with 18 multi-PMT digital optical modules. The first phase of construction has started and shore and deep-sea infrastructures hosting the future KM3NeT detector are being prepared in France near Toulon and in Italy, near Capo Passero in Sicily. The technological solutions for KM3NeT and the expected performance of the detector are presented and discussed.

Routing channels in VLSI layout

NASA Astrophysics Data System (ADS)

Cai, Hong

A number of algorithms for the automatic routing of interconnections in Very Large Scale Integration (VLSI) building-block layouts are presented. Algorithms for the topological definition of channels, the global routing and the geometrical definition of channels are presented. In contrast to traditional approaches the definition and ordering of the channels is done after the global routing. This approach has the advantage that global routing information can be taken into account to select the optimal channel structure. A polynomial algorithm for the channel definition and ordering problem is presented. The existence of a conflict-free channel structure is guaranteed by enforcing a sliceable placement. Algorithms for finding the shortest connection path are described. A separate algorithm is developed for the power net routing, because the two power nets must be planarly routed with variable wire width. An integrated placement and routing system for generating building-block layout is briefly described. Some experimental results and design experiences in using the system are also presented. Very good results are obtained.

Is the "Net Generation" Ready for Digital Citizenship? Perspectives from the IEA International Computer and Information Literacy Study 2013. Policy Brief No. 6

ERIC Educational Resources Information Center

Watkins, Ryan; Engel, Laura C.; Hastedt, Dirk

2015-01-01

The rise of digital information and communication technologies (ICT) has made the acquisition of computer and information literacy (CIL) a leading factor in creating an engaged, informed, and employable citizenry. However, are young people, often described as "digital natives" or the "net generation," developing the necessary…

The Net Generation in Japan: A Survey of Internet Behaviours of Students Aged 13-21

ERIC Educational Resources Information Center

Taynton, Keith

2012-01-01

Evidence from research into the "net generation" has shown it is not certain that there is a homogenous group of young people whose abilities to use technology are different from any other age group. With tools like blogs and online research becoming more popular in educational contexts research needs to provide a picture of what kinds…

Net energy output from harvesting small-diameter trees using a mechanized system

Treesearch

Fei Pan; Han-Sup Han; Leonard R. Johnson; William J. Elliot

2008-01-01

What amount of extra energy can be generated after subtracting the total energy consumed to produce the biomass energy? Knowing the ratio between energy output and input is a valid question when highly mechanized systems that consume fossil fuels are used to harvest and transport forest biomass for energy. We estimated the net energy generated from mechanical fuel...

Holmes: a graphical tool for development, simulation and analysis of Petri net based models of complex biological systems.

PubMed

Radom, Marcin; Rybarczyk, Agnieszka; Szawulak, Bartlomiej; Andrzejewski, Hubert; Chabelski, Piotr; Kozak, Adam; Formanowicz, Piotr

2017-12-01

Model development and its analysis is a fundamental step in systems biology. The theory of Petri nets offers a tool for such a task. Since the rapid development of computer science, a variety of tools for Petri nets emerged, offering various analytical algorithms. From this follows a problem of using different programs to analyse a single model. Many file formats and different representations of results make the analysis much harder. Especially for larger nets the ability to visualize the results in a proper form provides a huge help in the understanding of their significance. We present a new tool for Petri nets development and analysis called Holmes. Our program contains algorithms for model analysis based on different types of Petri nets, e.g. invariant generator, Maximum Common Transitions (MCT) sets and cluster modules, simulation algorithms or knockout analysis tools. A very important feature is the ability to visualize the results of almost all analytical modules. The integration of such modules into one graphical environment allows a researcher to fully devote his or her time to the model building and analysis. Available at http://www.cs.put.poznan.pl/mradom/Holmes/holmes.html. piotr@cs.put.poznan.pl. © The Author (2017). Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com

NETS

NASA Technical Reports Server (NTRS)

Baffes, Paul T.

1993-01-01

NETS development tool provides environment for simulation and development of neural networks - computer programs that "learn" from experience. Written in ANSI standard C, program allows user to generate C code for implementation of neural network.

Controlling the net charge on a nanoparticle optically levitated in vacuum

NASA Astrophysics Data System (ADS)

Frimmer, Martin; Luszcz, Karol; Ferreiro, Sandra; Jain, Vijay; Hebestreit, Erik; Novotny, Lukas

2017-06-01

Optically levitated nanoparticles in vacuum are a promising model system to test physics beyond our current understanding of quantum mechanics. Such experimental tests require extreme control over the dephasing of the levitated particle's motion. If the nanoparticle carries a finite net charge, it experiences a random Coulomb force due to fluctuating electric fields. This dephasing mechanism can be fully excluded by discharging the levitated particle. Here, we present a simple and reliable technique to control the charge on an optically levitated nanoparticle in vacuum. Our method is based on the generation of charges in an electric discharge and does not require additional optics or mechanics close to the optical trap.

SpectralNET – an application for spectral graph analysis and visualization

PubMed Central

Forman, Joshua J; Clemons, Paul A; Schreiber, Stuart L; Haggarty, Stephen J

2005-01-01

Background Graph theory provides a computational framework for modeling a variety of datasets including those emerging from genomics, proteomics, and chemical genetics. Networks of genes, proteins, small molecules, or other objects of study can be represented as graphs of nodes (vertices) and interactions (edges) that can carry different weights. SpectralNET is a flexible application for analyzing and visualizing these biological and chemical networks. Results Available both as a standalone .NET executable and as an ASP.NET web application, SpectralNET was designed specifically with the analysis of graph-theoretic metrics in mind, a computational task not easily accessible using currently available applications. Users can choose either to upload a network for analysis using a variety of input formats, or to have SpectralNET generate an idealized random network for comparison to a real-world dataset. Whichever graph-generation method is used, SpectralNET displays detailed information about each connected component of the graph, including graphs of degree distribution, clustering coefficient by degree, and average distance by degree. In addition, extensive information about the selected vertex is shown, including degree, clustering coefficient, various distance metrics, and the corresponding components of the adjacency, Laplacian, and normalized Laplacian eigenvectors. SpectralNET also displays several graph visualizations, including a linear dimensionality reduction for uploaded datasets (Principal Components Analysis) and a non-linear dimensionality reduction that provides an elegant view of global graph structure (Laplacian eigenvectors). Conclusion SpectralNET provides an easily accessible means of analyzing graph-theoretic metrics for data modeling and dimensionality reduction. SpectralNET is publicly available as both a .NET application and an ASP.NET web application from . Source code is available upon request. PMID:16236170

SpectralNET--an application for spectral graph analysis and visualization.

PubMed

Forman, Joshua J; Clemons, Paul A; Schreiber, Stuart L; Haggarty, Stephen J

2005-10-19

Graph theory provides a computational framework for modeling a variety of datasets including those emerging from genomics, proteomics, and chemical genetics. Networks of genes, proteins, small molecules, or other objects of study can be represented as graphs of nodes (vertices) and interactions (edges) that can carry different weights. SpectralNET is a flexible application for analyzing and visualizing these biological and chemical networks. Available both as a standalone .NET executable and as an ASP.NET web application, SpectralNET was designed specifically with the analysis of graph-theoretic metrics in mind, a computational task not easily accessible using currently available applications. Users can choose either to upload a network for analysis using a variety of input formats, or to have SpectralNET generate an idealized random network for comparison to a real-world dataset. Whichever graph-generation method is used, SpectralNET displays detailed information about each connected component of the graph, including graphs of degree distribution, clustering coefficient by degree, and average distance by degree. In addition, extensive information about the selected vertex is shown, including degree, clustering coefficient, various distance metrics, and the corresponding components of the adjacency, Laplacian, and normalized Laplacian eigenvectors. SpectralNET also displays several graph visualizations, including a linear dimensionality reduction for uploaded datasets (Principal Components Analysis) and a non-linear dimensionality reduction that provides an elegant view of global graph structure (Laplacian eigenvectors). SpectralNET provides an easily accessible means of analyzing graph-theoretic metrics for data modeling and dimensionality reduction. SpectralNET is publicly available as both a .NET application and an ASP.NET web application from http://chembank.broad.harvard.edu/resources/. Source code is available upon request.

Simulation of vehicle acoustics in support of netted sensor research and development

NASA Astrophysics Data System (ADS)

Christou, Carol T.; Jacyna, Garry M.

2005-05-01

The MITRE Corporation has initiated a three-year internally-funded research program in netted sensors, the first-year effort focusing on vehicle detection for border monitoring. An important component is developing an understanding of the complex acoustic structure of vehicle noise to aid in netted sensor-based detection and classification. This presentation will discuss the design of a high-fidelity vehicle acoustic simulator to model the generation and transmission of acoustic energy from a moving vehicle to a collection of sensor nodes. Realistic spatially-dependent automobile sounds are generated from models of the engine cylinder firing rates, muffler and manifold resonances, and speed-dependent tire whine noise. Tire noise is the dominant noise source for vehicle speeds in excess of 30 miles per hour (MPH). As a result, we have developed detailed models that successfully predict the tire noise spectrum as a function of speed, road surface wave-number spectrum, tire geometry, and tire tread pattern. We have also included realistic descriptions of the spatial directivity patterns for the engine harmonics, muffler, and tire whine noise components. The acoustic waveforms are propagated to each sensor node using a simple phase-dispersive multi-path model. A brief description of the models and their corresponding outputs is provided.

The Impact of Rate Design and Net Metering on the Bill Savings from Distributed PV for Residential Customers in California

DOE Office of Scientific and Technical Information (OSTI.GOV)

Darghouth, Naim; Barbose, Galen; Wiser, Ryan

2010-03-30

Net metering has become a widespread policy in the U.S. for supporting distributed photovoltaics (PV) adoption. Though specific design details vary, net metering allows customers with PV to reduce their electric bills by offsetting their consumption with PV generation, independent of the timing of the generation relative to consumption - in effect, compensating the PV generation at retail electricity rates (Rose et al. 2009). While net metering has played an important role in jump-starting the residential PV market in the U.S., challenges to net metering policies have emerged in a number of states and contexts, and alternative compensation methods aremore » under consideration. Moreover, one inherent feature of net metering is that the value of the utility bill savings it provides to customers with PV depends heavily on the structure of the underlying retail electricity rate, as well as on the characteristics of the customer and PV system. Consequently, the value of net metering - and the impact of moving to alternative compensation mechanisms - can vary substantially from one customer to the next. For these reasons, it is important for policymakers and others that seek to support the development of distributed PV to understand both how the bill savings varies under net metering, and how the bill savings under net metering compares to other possible compensation mechanisms. To advance this understanding, we analyze the bill savings from PV for residential customers of California's two largest electric utilities, Pacific Gas and Electric (PG&E) and Southern California Edison (SCE). The analysis is based on hourly load data from a sample of 215 residential customers located in the service territories of the two utilities, matched with simulated hourly PV production for the same time period based on data from the nearest of 73 weather stations in the state.« less

[Study on single-walled carbon nanotube thin film photoelectric device].

PubMed

Xie, Wen-bin; Zhu, Yong; Gong, Tian-cheng; Chen, Yu-lin; Zhang, Jie

2015-01-01

The single-walled carbon nanotube film photoelectric device was invented, and it can generate net photocurrent under bias voltage when it is illuminated by the laser. The influences of bias voltage, laser power and illuminating position on the net photocurrent were investigated. The experimental results showed that when the center of the film was illuminated, the photocurrent increased with the applied bias, but tended to saturate as the laser power increased. As the voltage and the laser power reached 0. 2 V and 22. 7 mW respectively, the photocurrent reached 0. 24 µA. When the voltage was removed, the photocurrent varied with the laser illuminating position on the film and its value was distributed symmetrically about the center of the device. The photocurrent reached maximum and almost zero respectively when the laser illuminated on two ends and the center of the film. Analysis proposes that the net photocurrent can be generated due to internal photoelectric effect when the device is under voltage and the laser illuminates on the center of the film. It can be also generated due to photo-thermoelectric effect when the device is under no voltage and the laser illuminates on the film, and the relation between the net photocurrent and the illuminating position was derived according to the nature of thermoelectric power of single-walled carbon nanotubes with the established temperature model, which coincides with experimental result. Two effects are the reasons for the generation and variety of the net photocurrent and they superimpose to form the result of the net photocurrent when the device is under general conditions of voltage and laser illuminating position. The device has potential applications in the areas of photovoltaic device and optical sensor for its characteristic.

SeaDataCloud - further developing the pan-European SeaDataNet infrastructure for marine and ocean data management

NASA Astrophysics Data System (ADS)

Schaap, Dick M. A.; Fichaut, Michele

2017-04-01

SeaDataCloud marks the third phase of developing the pan-European SeaDataNet infrastructure for marine and ocean data management. The SeaDataCloud project is funded by EU and runs for 4 years from 1st November 2016. It succeeds the successful SeaDataNet II (2011 - 2015) and SeaDataNet (2006 - 2011) projects. SeaDataNet has set up and operates a pan-European infrastructure for managing marine and ocean data and is undertaken by National Oceanographic Data Centres (NODC's) and oceanographic data focal points from 34 coastal states in Europe. The infrastructure comprises a network of interconnected data centres and central SeaDataNet portal. The portal provides users a harmonised set of metadata directories and controlled access to the large collections of datasets, managed by the interconnected data centres. The population of directories has increased considerably in cooperation with and involvement in many associated EU projects and initiatives such as EMODnet. SeaDataNet at present gives overview and access to more than 1.9 million data sets for physical oceanography, chemistry, geology, geophysics, bathymetry and biology from more than 100 connected data centres from 34 countries riparian to European seas. SeaDataNet is also active in setting and governing marine data standards, and exploring and establishing interoperability solutions to connect to other e-infrastructures on the basis of standards of ISO (19115, 19139), and OGC (WMS, WFS, CS-W and SWE). Standards and associated SeaDataNet tools are made available at the SeaDataNet portal for wide uptake by data handling and managing organisations. SeaDataCloud aims at further developing standards, innovating services & products, adopting new technologies, and giving more attention to users. Moreover, it is about implementing a cooperation between the SeaDataNet consortium of marine data centres and the EUDAT consortium of e-infrastructure service providers. SeaDataCloud aims at considerably advancing services and increasing their usage by adopting cloud and High Performance Computing technology. SeaDataCloud will empower researchers with a packaged collection of services and tools, tailored to their specific needs, supporting research and enabling generation of added-value products from marine and ocean data. Substantial activities will be focused on developing added-value services, such as data subsetting, analysis, visualisation, and publishing workflows for users, both regular and advanced users, as part of a Virtual Research Environment (VRE). SeaDataCloud aims at a number of leading user communities that have new challenges for upgrading and expanding the SeaDataNet standards and services: Science, EMODnet, Copernicus Marine Environmental Monitoring Service (CMEMS) and EuroGOOS, and International scientific programmes. The presentation will give information on present services of the SeaDataNet infrastructure and services, and the new challenges in SeaDataCloud, and will highlight a number of key achievements in SeaDataCloud so far.

Neural network error correction for solving coupled ordinary differential equations

NASA Technical Reports Server (NTRS)

Shelton, R. O.; Darsey, J. A.; Sumpter, B. G.; Noid, D. W.

1992-01-01

A neural network is presented to learn errors generated by a numerical algorithm for solving coupled nonlinear differential equations. The method is based on using a neural network to correctly learn the error generated by, for example, Runge-Kutta on a model molecular dynamics (MD) problem. The neural network programs used in this study were developed by NASA. Comparisons are made for training the neural network using backpropagation and a new method which was found to converge with fewer iterations. The neural net programs, the MD model and the calculations are discussed.

Valuing Trial Designs from a Pharmaceutical Perspective Using Value-Based Pricing.

PubMed

Breeze, Penny; Brennan, Alan

2015-11-01

Our aim was to adapt the traditional framework for expected net benefit of sampling (ENBS) to be more compatible with drug development trials from the pharmaceutical perspective. We modify the traditional framework for conducting ENBS and assume that the price of the drug is conditional on the trial outcomes. We use a value-based pricing (VBP) criterion to determine price conditional on trial data using Bayesian updating of cost-effectiveness (CE) model parameters. We assume that there is a threshold price below which the company would not market the new intervention. We present a case study in which a phase III trial sample size and trial duration are varied. For each trial design, we sampled 10,000 trial outcomes and estimated VBP using a CE model. The expected commercial net benefit is calculated as the expected profits minus the trial costs. A clinical trial with shorter follow-up, and larger sample size, generated the greatest expected commercial net benefit. Increasing the duration of follow-up had a modest impact on profit forecasts. Expected net benefit of sampling can be adapted to value clinical trials in the pharmaceutical industry to optimise the expected commercial net benefit. However, the analyses can be very time consuming for complex CE models. © 2014 The Authors. Health Economics published by John Wiley & Sons Ltd.

Successfully Implementing Net-Zero Energy Policy through the Air Force Military Construction Program

DTIC Science & Technology

2013-03-01

Meets Does not meet Does not meet Meets Renewable Farms Meets Meets Meets Meets On-Site (Distributed Generation) Meets* Meets* Meets Meets...independence, nor does it allow for net-zero energy installations. Developing centralized renewable energy farms is another method for obtaining...combination of centralized renewable energy farms and distributed generation methods. The specific combination of methods an installation will utilize

The cost of a small membrane bioreactor.

PubMed

Lo, C H; McAdam, E; Judd, S

2015-01-01

The individual cost contributions to the mechanical components of a small membrane bioreactor (MBR) (100-2,500 m3/d flow capacity) are itemised and collated to generate overall capital and operating costs (CAPEX and OPEX) as a function of size. The outcomes are compared to those from previously published detailed cost studies provided for both very small containerised plants (<40 m3/day capacity) and larger municipal plants (2,200-19,000 m3/d). Cost curves, as a function of flow capacity, determined for OPEX, CAPEX and net present value (NPV) based on the heuristic data used indicate a logarithmic function for OPEX and a power-based one for the CAPEX. OPEX correlations were in good quantitative agreement with those reported in the literature. Disparities in the calculated CAPEX trend compared with reported data were attributed to differences in assumptions concerning cost contributions. More reasonable agreement was obtained with the reported membrane separation component CAPEX data from published studies. The heuristic approach taken appears appropriate for small-scale MBRs with minimal costs associated with installation. An overall relationship of net present value=(a tb)Q(-c lnt+d) was determined for the net present value where a=1.265, b=0.44, c=0.00385 and d=0.868 according to the dataset employed for the analysis.

Connecticut | Midmarket Solar Policies in the United States | Solar

Science.gov Websites

(RECs) Meter aggregation: Virtual net metering allowed for state, municipal, and agricultural customers " under a state, municipal, or agricultural host under certain conditions. Net excess generation

A new variant of Petri net controlled grammars

NASA Astrophysics Data System (ADS)

Jan, Nurhidaya Mohamad; Turaev, Sherzod; Fong, Wan Heng; Sarmin, Nor Haniza

2015-10-01

A Petri net controlled grammar is a Petri net with respect to a context-free grammar where the successful derivations of the grammar can be simulated using the occurrence sequences of the net. In this paper, we introduce a new variant of Petri net controlled grammars, called a place-labeled Petri net controlled grammar, which is a context-free grammar equipped with a Petri net and a function which maps places of the net to productions of the grammar. The language consists of all terminal strings that can be obtained by parallelly applying multisets of the rules which are the images of the sets of the input places of transitions in a successful occurrence sequence of the Petri net. We study the effect of the different labeling strategies to the computational power and establish lower and upper bounds for the generative capacity of place-labeled Petri net controlled grammars.

An Agro-Climatological Early Warning Tool Based on the Google Earth Engine to Support Regional Food Security Analysis

NASA Astrophysics Data System (ADS)

Landsfeld, M. F.; Daudert, B.; Friedrichs, M.; Morton, C.; Hegewisch, K.; Husak, G. J.; Funk, C. C.; Peterson, P.; Huntington, J. L.; Abatzoglou, J. T.; Verdin, J. P.; Williams, E. L.

2015-12-01

The Famine Early Warning Systems Network (FEWS NET) focuses on food insecurity in developing nations and provides objective, evidence based analysis to help government decision-makers and relief agencies plan for and respond to humanitarian emergencies. The Google Earth Engine (GEE) is a platform provided by Google Inc. to support scientific research and analysis of environmental data in their cloud environment. The intent is to allow scientists and independent researchers to mine massive collections of environmental data and leverage Google's vast computational resources to detect changes and monitor the Earth's surface and climate. GEE hosts an enormous amount of satellite imagery and climate archives, one of which is the Climate Hazards Group Infrared Precipitation with Stations dataset (CHIRPS). The CHIRPS dataset is land based, quasi-global (latitude 50N-50S), 0.05 degree resolution, and has a relatively long term period of record (1981-present). CHIRPS is on a continuous monthly feed into the GEE as new data fields are generated each month. This precipitation dataset is a key input for FEWS NET monitoring and forecasting efforts. FEWS NET intends to leverage the GEE in order to provide analysts and scientists with flexible, interactive tools to aid in their monitoring and research efforts. These scientists often work in bandwidth limited regions, so lightweight Internet tools and services that bypass the need for downloading massive datasets to analyze them, are preferred for their work. The GEE provides just this type of service. We present a tool designed specifically for FEWS NET scientists to be utilized interactively for investigating and monitoring for agro-climatological issues. We are able to utilize the enormous GEE computing power to generate on-the-fly statistics to calculate precipitation anomalies, z-scores, percentiles and band ratios, and allow the user to interactively select custom areas for statistical time series comparisons and predictions.

Enabling technologies for millimeter-wave radio-over-fiber systems in next generation heterogeneous mobile access networks

NASA Astrophysics Data System (ADS)

Zhang, Junwen; Yu, Jianjun; Wang, Jing; Xu, Mu; Cheng, Lin; Lu, Feng; Shen, Shuyi; Yan, Yan; Cho, Hyunwoo; Guidotti, Daniel; Chang, Gee-kung

2017-01-01

Fifth-generation (5G) wireless access network promises to support higher access data rate with more than 1,000 times capacity with respect to current long-term evolution (LTE) systems. New radio-access-technologies (RATs) based on higher carrier frequencies to millimeter-wave (MMW) radio-over-fiber, and carrier-aggregation (CA) using multi-band resources are intensively studied to support the high data rate access and effectively use of frequency resources in heterogeneous mobile network (Het-Net). In this paper, we investigate several enabling technologies for MMW RoF systems in 5G Het-Net. Efficient mobile fronthaul (MFH) solutions for 5G centralized radio access network (C-RAN) and beyond are proposed, analyzed and experimentally demonstrated based on the analog scheme. Digital predistortion based on memory polynomial for analog MFH linearization are presented with improved EVM performances and receiver sensitivity. We also propose and experimentally demonstrate a novel inter-/intra- RAT CA scheme for 5G Het- Net. The real-time standard 4G-LTE signal is carrier-aggregated with three broadband 60GHz MMW signals based on proposed optical-domain band-mapping method. RATs based on new waveforms have also been studied here to achieve higher spectral-efficiency (SE) in asynchronous environments. Full-duplex asynchronous quasi-gapless carrier aggregation scheme for MMW ROF inter-/intra-RAT based on the FBMC is also presented with 4G-LTE signals. Compared with OFDM-based signals with large guard-bands, FBMC achieves higher spectral-efficiency with better EVM performance at less received power and smaller guard-bands.

The Neutrophil’s Choice: Phagocytose vs Make Neutrophil Extracellular Traps

PubMed Central

Manfredi, Angelo A.; Ramirez, Giuseppe A.; Rovere-Querini, Patrizia; Maugeri, Norma

2018-01-01

Neutrophils recognize particulate substrates of microbial or endogenous origin and react by sequestering the cargo via phagocytosis or by releasing neutrophil extracellular traps (NETs) outside the cell, thus modifying and alerting the environment and bystander leukocytes. The signals that determine the choice between phagocytosis and the generation of NETs are still poorly characterized. Neutrophils that had phagocytosed bulky particulate substrates, such as apoptotic cells and activated platelets, appear to be “poised” in an unresponsive state. Environmental conditions, the metabolic, adhesive and activation state of the phagocyte, and the size of and signals associated with the tethered phagocytic cargo influence the choice of the neutrophils, prompting either phagocytic clearance or the generation of NETs. The choice is dichotomic and apparently irreversible. Defects in phagocytosis may foster the intravascular generation of NETs, thus promoting vascular inflammation and morbidities associated with diseases characterized by defective phagocytic clearance, such as systemic lupus erythematosus. There is a strong potential for novel treatments based on new knowledge of the events determining the inflammatory and pro-thrombotic function of inflammatory leukocytes. PMID:29515586

Is there a "net generation" in veterinary medicine? A comparative study on the use of the Internet and Web 2.0 by students and the veterinary profession.

PubMed

Tenhaven, Christoph; Tipold, Andrea; Fischer, Martin R; Ehlers, Jan P

2013-01-01

Informal and formal lifelong learning is essential at university and in the workplace. Apart from classical learning techniques, Web 2.0 tools can be used. It is controversial whether there is a so-called net generation amongst people under 30. To test the hypothesis that a net generation among students and young veterinarians exists. An online survey of students and veterinarians was conducted in the German-speaking countries which was advertised via online media and traditional print media. 1780 people took part in the survey. Students and veterinarians have different usage patterns regarding social networks (91.9% vs. 69%) and IM (55.9% vs. 24.5%). All tools were predominantly used passively and in private, to a lesser extent also professionally and for studying. The use of Web 2.0 tools is useful, however, teaching information and media skills, preparing codes of conduct for the internet and verification of user generated content is essential.

Sub-100 fs pulses from an all-polarization maintaining Yb-fiber oscillator with an anomalous dispersion higher-order-mode fiber.

PubMed

Verhoef, A J; Zhu, L; Israelsen, S Møller; Grüner-Nielsen, L; Unterhuber, A; Kautek, W; Rottwitt, K; Baltuška, A; Fernández, A

2015-10-05

We present an Yb-fiber oscillator with an all-polarization-maintaining cavity with a higher-order-mode fiber for dispersion compensation. The polarization maintaining higher order mode fiber introduces not only negative second order dispersion but also negative third order dispersion in the cavity, in contrast to dispersion compensation schemes used in previous demonstrations of all-polarization maintaining Yb-fiber oscillators. The performance of the saturable absorber mirror modelocked oscillator, that employs a free space scheme for coupling onto the saturable absorber mirror and output coupling, was investigated for different settings of the intracavity dispersion. When the cavity is operated with close to zero net dispersion, highly stable 0.5-nJ pulses externally compressed to sub-100-fs are generated. These are to our knowledge the shortest pulses generated from an all-polarization-maintaining Yb-fiber oscillator. The spectral phase of the output pulses is well behaved and can be compensated such that wing-free Fourier transform limited pulses can be obtained. Further reduction of the net intracavity third order dispersion will allow generating broader output spectra and consequently shorter pulses, without sacrificing pulse fidelity.

Modification of Impulse Generation During Pirouette Turns With Increased Rotational Demands.

PubMed

Zaferiou, Antonia M; Wilcox, Rand R; McNitt-Gray, Jill L

2016-10-01

This study determined how dancers regulated angular and linear impulse during the initiation of pirouettes of increased rotation. Skilled dancers (n = 11) performed single and double pirouette turns with each foot supported by a force plate. Linear and angular impulses generated by each leg were quantified and compared between turn types using probability-based statistical methods. As rotational demands increased, dancers increased the net angular impulse generated. The contribution of each leg to net angular impulse in both single and double pirouettes was influenced by stance configuration strategies. Dancers who generated more angular impulse with the push leg than with the turn leg initiated the turn with the center of mass positioned closer to the turn leg than did other dancers. As rotational demands increased, dancers tended to increase the horizontal reaction force magnitude at one or both feet; however, they used subject-specific mechanisms. By coordinating the generation of reaction forces between legs, changes in net horizontal impulse remained minimal, despite impulse regulation at each leg used to achieve more rotations. Knowledge gained regarding how an individual coordinates the generation of linear and angular impulse between both legs as rotational demand increased can help design tools to improve that individual's performance.

Fault Diagnosis System of Wind Turbine Generator Based on Petri Net

NASA Astrophysics Data System (ADS)

Zhang, Han

Petri net is an important tool for discrete event dynamic systems modeling and analysis. And it has great ability to handle concurrent phenomena and non-deterministic phenomena. Currently Petri nets used in wind turbine fault diagnosis have not participated in the actual system. This article will combine the existing fuzzy Petri net algorithms; build wind turbine control system simulation based on Siemens S7-1200 PLC, while making matlab gui interface for migration of the system to different platforms.

Coverability graphs for a class of synchronously executed unbounded Petri net

NASA Technical Reports Server (NTRS)

Stotts, P. David; Pratt, Terrence W.

1990-01-01

After detailing a variant of the concurrent-execution rule for firing of maximal subsets, in which the simultaneous firing of conflicting transitions is prohibited, an algorithm is constructed for generating the coverability graph of a net executed under this synchronous firing rule. The omega insertion criteria in the algorithm are shown to be valid for any net on which the algorithm terminates. It is accordingly shown that the set of nets on which the algorithm terminates includes the 'conflict-free' class.

Uncertainties in the Value of Bill Savings from Behind-the-Meter, Residential Photovoltaic Systems: The Roles of Electricity Market Conditions, Retail Rate Design, and Net Metering

NASA Astrophysics Data System (ADS)

Darghouth, Naim Richard

Net metering has become a widespread policy mechanism in the U.S. for supporting customer adoption of distributed photovoltaics (PV), allowing customers with PV systems to reduce their electric bills by offsetting their consumption with PV generation, independent of the timing of the generation relative to consumption. Although net metering is one of the principal drivers for the residential PV market in the U.S., the academic literature on this policy has been sparse and this dissertation contributes to this emerging body of literature. This dissertation explores the linkages between the availability of net metering, wholesale electricity market conditions, retail rates, and the residential bill savings from behind-the-meter PV systems. First, I examine the value of the bill savings that customers receive under net metering and alternatives to net metering, and the associated role of retail rate design, based on current rates and a sample of approximately two hundred residential customers of California's two largest electric utilities. I find that the bill savings per kWh of PV electricity generated varies greatly, largely attributable to the increasing block structure of the California utilities' residential retail rates. I also find that net metering provides significantly greater bill savings than alternative compensation mechanisms based on avoided costs. However, retail electricity rates may shift as wholesale electricity market conditions change. I then investigate a potential change in market conditions -- increased solar PV penetrations -- on wholesale prices in the short-term based on the merit-order effect. This demonstrates the potential price effects of changes in market conditions, but also points to a number of methodological shortcomings of this method, motivating my usage of a long-term capacity investment and economic dispatch model to examine wholesale price effects of various wholesale market scenarios in the subsequent analysis. By developing three types of retail rates (a flat rate, a time-of-use rate, and real-time pricing) from these wholesale price profiles, I examine bill savings from PV generation for the ten wholesale market scenarios under net metering and an alternative to net metering where hourly excess PV generation is compensated at the wholesale price. Most generally, I challenge the common assertion that PV compensation is likely to stay constant (or rise) due to constant (or rising) retail rates, and find that future electricity market scenarios can drive substantial changes in residential retail rates and that these changes, in concert with variations in retail rate structures and PV compensation mechanisms, interact to place substantial uncertainty on the future value of bill savings from residential PV.

Reachability analysis of real-time systems using time Petri nets.

PubMed

Wang, J; Deng, Y; Xu, G

2000-01-01

Time Petri nets (TPNs) are a popular Petri net model for specification and verification of real-time systems. A fundamental and most widely applied method for analyzing Petri nets is reachability analysis. The existing technique for reachability analysis of TPNs, however, is not suitable for timing property verification because one cannot derive end-to-end delay in task execution, an important issue for time-critical systems, from the reachability tree constructed using the technique. In this paper, we present a new reachability based analysis technique for TPNs for timing property analysis and verification that effectively addresses the problem. Our technique is based on a concept called clock-stamped state class (CS-class). With the reachability tree generated based on CS-classes, we can directly compute the end-to-end time delay in task execution. Moreover, a CS-class can be uniquely mapped to a traditional state class based on which the conventional reachability tree is constructed. Therefore, our CS-class-based analysis technique is more general than the existing technique. We show how to apply this technique to timing property verification of the TPN model of a command and control (C2) system.

Hydrogen-based power generation from bioethanol steam reforming

NASA Astrophysics Data System (ADS)

Tasnadi-Asztalos, Zs.; Cormos, C. C.; Agachi, P. S.

2015-12-01

This paper is evaluating two power generation concepts based on hydrogen produced from bioethanol steam reforming at industrial scale without and with carbon capture. The power generation from bioethanol conversion is based on two important steps: hydrogen production from bioethanol catalytic steam reforming and electricity generation using a hydrogen-fuelled gas turbine. As carbon capture method to be assessed in hydrogen-based power generation from bioethanol steam reforming, the gas-liquid absorption using methyl-di-ethanol-amine (MDEA) was used. Bioethanol is a renewable energy carrier mainly produced from biomass fermentation. Steam reforming of bioethanol (SRE) provides a promising method for hydrogen and power production from renewable resources. SRE is performed at high temperatures (e.g. 800-900°C) to reduce the reforming by-products (e.g. ethane, ethene). The power generation from hydrogen was done with M701G2 gas turbine (334 MW net power output). Hydrogen was obtained through catalytic steam reforming of bioethanol without and with carbon capture. For the evaluated plant concepts the following key performance indicators were assessed: fuel consumption, gross and net power outputs, net electrical efficiency, ancillary consumptions, carbon capture rate, specific CO2 emission etc. As the results show, the power generation based on bioethanol conversion has high energy efficiency and low carbon footprint.

Hydrogen-based power generation from bioethanol steam reforming

DOE Office of Scientific and Technical Information (OSTI.GOV)

Tasnadi-Asztalos, Zs., E-mail: tazsolt@chem.ubbcluj.ro; Cormos, C. C., E-mail: cormos@chem.ubbcluj.ro; Agachi, P. S.

This paper is evaluating two power generation concepts based on hydrogen produced from bioethanol steam reforming at industrial scale without and with carbon capture. The power generation from bioethanol conversion is based on two important steps: hydrogen production from bioethanol catalytic steam reforming and electricity generation using a hydrogen-fuelled gas turbine. As carbon capture method to be assessed in hydrogen-based power generation from bioethanol steam reforming, the gas-liquid absorption using methyl-di-ethanol-amine (MDEA) was used. Bioethanol is a renewable energy carrier mainly produced from biomass fermentation. Steam reforming of bioethanol (SRE) provides a promising method for hydrogen and power production frommore » renewable resources. SRE is performed at high temperatures (e.g. 800-900°C) to reduce the reforming by-products (e.g. ethane, ethene). The power generation from hydrogen was done with M701G2 gas turbine (334 MW net power output). Hydrogen was obtained through catalytic steam reforming of bioethanol without and with carbon capture. For the evaluated plant concepts the following key performance indicators were assessed: fuel consumption, gross and net power outputs, net electrical efficiency, ancillary consumptions, carbon capture rate, specific CO{sub 2} emission etc. As the results show, the power generation based on bioethanol conversion has high energy efficiency and low carbon footprint.« less

Evaluation of pyritic mine tailings as a plant growth substrate.

PubMed

Roseby, Stuart J; Kopittke, Peter M; Mulligan, David R; Menzies, Neal W

2017-10-01

At the Kidston gold mine, Australia, the direct establishment of vegetation on tailings was considered as an alternative to the use of a waste rock cover. The tailings acid/base account was used to predict plant growth limitation by acidity, and thus methods capable of identifying tailings that would acidify to pH 4.5 or lower were sought. Total S was found to be poorly correlated with acid-generating sulfide, and total C was poorly correlated with acid-neutralizing carbonate, precluding the use of readily determined total S and C as predictors of net acid generation. Therefore, the selected approach used assessment of sulfide content as a predictor of acid generation, and carbonate content as a measure of the acid-neutralizing capacity available at pH 5 and above. Using this approach, the majority of tailings (67%) were found to be non-acid generating. However, areas of potentially acid-generating tailings were randomly distributed across the dam, and could only be located by intensive sampling. The limitations imposed by the large sample numbers, and costly analysis of sulfide and carbonate, make it impractical to identify and ameliorate acid-generating areas prior to vegetation establishment. However, as only a small proportion of the tailings will acidify, a strategy of re-treating acid areas following oxidation is suggested. The findings of the present study will assist in the selection of appropriate methods for the prediction of net acid generation, particularly where more conservative measurements are required to allow vegetation to be established directly in tailings. Copyright © 2017 Elsevier Ltd. All rights reserved.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Diakov, Victor; Brinkman, Gregory; Denholm, Paul

Using production-cost model (PLEXOS), we simulate the Western Interchange (WECC) at several levels of the yearly renewable energy (RE) generation, between 13% and 40% of the total load for the year. We look at the overall energy exchange between a region and the rest of the system (net interchange, NI), and find it useful to examine separately (i) (time-)variable and (ii) year-average components of the NI. Both contribute to inter-regional energy exchange, and are affected by wind and PV generation in the system. We find that net load variability (in relatively large portions of WECC) is the leading factor affectingmore » the variable component of inter-regional energy exchange, and the effect is quantifiable: higher regional net load correlation with the rest of the WECC lowers net interchange variability. Further, as the power mix significantly varies between WECC regions, effects of ‘flexibility import’ (regions ‘borrow’ ramping capability) are also observed.« less

Grid-Connected Distributed Generation: Compensation Mechanism Basics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Aznar, Alexandra Y; Zinaman, Owen R

2017-10-02

This short report defines compensation mechanisms for grid-connected, behind-the-meter distributed generation (DG) systems as instruments that comprise three core elements: (1) metering and billing arrangements, (2) sell rate design, and (3) retail rate design. This report describes metering and billing arrangements, with some limited discussion of sell rate design. We detail the three possible arrangements for metering and billing of DG: net energy metering (NEM); buy all, sell all; and net billing.

The Analysis of Information Exchange Capability for Battlefield Networks Using M&S Techniques of the NetSPIN

DTIC Science & Technology

2013-06-01

of the ATCIS in the NetSPIN Name Main functions Terminal Functions as the terminal that generates traffics MFE (Multi-Function accessing...generates traffics : MFE Function to transform messages of SST into TCP liP packets (Multi-Function accessing Equipment) Termmal PPP Functions of the...center Operation battalion DMT Computer shelter DLP Operation center MFE DMTTerminal Command post of a corps Brigade communication Operation

Hardware Acceleration for Cyber Security

DTIC Science & Technology

2010-11-01

perform different approaches. It includes behavioral analysis, by means of NetFlow monitoring, as well as packet content analysis, so called Deep...Interface (API). The example of such application is NetFlow exporter described in [5]. • We provide modified libpcap library using libsze2 API. This...cards. The software applications using NIFIC include FlowMon NetFlow /IPFIX generator, Wireshark packet analyzer, iptables - Linux kernel firewall, deep

Uncertainty in predictions of forest carbon dynamics: separating driver error from model error.

PubMed

Spadavecchia, L; Williams, M; Law, B E

2011-07-01

We present an analysis of the relative magnitude and contribution of parameter and driver uncertainty to the confidence intervals on estimates of net carbon fluxes. Model parameters may be difficult or impractical to measure, while driver fields are rarely complete, with data gaps due to sensor failure and sparse observational networks. Parameters are generally derived through some optimization method, while driver fields may be interpolated from available data sources. For this study, we used data from a young ponderosa pine stand at Metolius, Central Oregon, and a simple daily model of coupled carbon and water fluxes (DALEC). An ensemble of acceptable parameterizations was generated using an ensemble Kalman filter and eddy covariance measurements of net C exchange. Geostatistical simulations generated an ensemble of meteorological driving variables for the site, consistent with the spatiotemporal autocorrelations inherent in the observational data from 13 local weather stations. Simulated meteorological data were propagated through the model to derive the uncertainty on the CO2 flux resultant from driver uncertainty typical of spatially extensive modeling studies. Furthermore, the model uncertainty was partitioned between temperature and precipitation. With at least one meteorological station within 25 km of the study site, driver uncertainty was relatively small ( 10% of the total net flux), while parameterization uncertainty was larger, 50% of the total net flux. The largest source of driver uncertainty was due to temperature (8% of the total flux). The combined effect of parameter and driver uncertainty was 57% of the total net flux. However, when the nearest meteorological station was > 100 km from the study site, uncertainty in net ecosystem exchange (NEE) predictions introduced by meteorological drivers increased by 88%. Precipitation estimates were a larger source of bias in NEE estimates than were temperature estimates, although the biases partly compensated for each other. The time scales on which precipitation errors occurred in the simulations were shorter than the temporal scales over which drought developed in the model, so drought events were reasonably simulated. The approach outlined here provides a means to assess the uncertainty and bias introduced by meteorological drivers in regional-scale ecological forecasting.

Bulk energy storage increases United States electricity system emissions.

PubMed

Hittinger, Eric S; Azevedo, Inês M L

2015-03-03

Bulk energy storage is generally considered an important contributor for the transition toward a more flexible and sustainable electricity system. Although economically valuable, storage is not fundamentally a "green" technology, leading to reductions in emissions. We model the economic and emissions effects of bulk energy storage providing an energy arbitrage service. We calculate the profits under two scenarios (perfect and imperfect information about future electricity prices), and estimate the effect of bulk storage on net emissions of CO2, SO2, and NOx for 20 eGRID subregions in the United States. We find that net system CO2 emissions resulting from storage operation are nontrivial when compared to the emissions from electricity generation, ranging from 104 to 407 kg/MWh of delivered energy depending on location, storage operation mode, and assumptions regarding carbon intensity. Net NOx emissions range from -0.16 (i.e., producing net savings) to 0.49 kg/MWh, and are generally small when compared to average generation-related emissions. Net SO2 emissions from storage operation range from -0.01 to 1.7 kg/MWh, depending on location and storage operation mode.

Submesoscale hotspots of productivity and respiration: Insights from high-resolution oxygen and fluorescence sections

NASA Astrophysics Data System (ADS)

Stanley, Rachel H. R.; McGillicuddy, Dennis J.; Sandwith, Zoe O.; Pleskow, Haley M.

2017-12-01

Modeling studies have shown that mesoscale and submesoscale processes can stimulate phytoplankton productivity and export production. Here, we present observations from an undulating, towed Video Plankton Recorder (VPR-II) in the tropical Atlantic. The VPR-II collected profiles of oxygen, fluorescence, temperature and salinity in the upper 140 m of the water column at a spatial resolution of 1 m in the vertical and <2 km in the horizontal. The data reveal remarkable "hotspots", i.e. locations 5-10 km wide which have elevated fluorescence and decreased oxygen, both of which are likely the result of intense submesoscale upwelling. Based on estimates of source water, estimated from identical temperature and salinity surfaces, hotspots are more often areas of net respiration than areas of net production - although the inferred changes in oxygen are subject to uncertainty in the determination of the source of the upwelled waters since the true source water may not have been sampled. We discuss the spatial distribution of these hotspots and present a conceptual model outlining their possible generation and decline. Simultaneous measurements of O2/Ar in the mixed layer from a shipboard mass spectrometer provide estimates of rates of surface net community production. We find that the subsurface biological hotspots are often expressed as an increase in mixed layer rates of net community production. Overall, the large number of these hotspots support the growing evidence that submesoscale processes are important drivers in upper ocean biological production.

Talkin' 'bout My Generation

ERIC Educational Resources Information Center

Rickes, Persis C.

2010-01-01

The monikers are many: (1) "Generation Y"; (2) "Echo Boomers"; (3) "GenMe"; (4) the "Net Generation"; (5) "RenGen"; and (6) "Generation Next". One name that appears to be gaining currency is "Millennials," perhaps as a way to better differentiate the current generation from its…

A Microsoft-Excel-based tool for running and critically appraising network meta-analyses--an overview and application of NetMetaXL.

PubMed

Brown, Stephen; Hutton, Brian; Clifford, Tammy; Coyle, Doug; Grima, Daniel; Wells, George; Cameron, Chris

2014-09-29

The use of network meta-analysis has increased dramatically in recent years. WinBUGS, a freely available Bayesian software package, has been the most widely used software package to conduct network meta-analyses. However, the learning curve for WinBUGS can be daunting, especially for new users. Furthermore, critical appraisal of network meta-analyses conducted in WinBUGS can be challenging given its limited data manipulation capabilities and the fact that generation of graphical output from network meta-analyses often relies on different software packages than the analyses themselves. We developed a freely available Microsoft-Excel-based tool called NetMetaXL, programmed in Visual Basic for Applications, which provides an interface for conducting a Bayesian network meta-analysis using WinBUGS from within Microsoft Excel. . This tool allows the user to easily prepare and enter data, set model assumptions, and run the network meta-analysis, with results being automatically displayed in an Excel spreadsheet. It also contains macros that use NetMetaXL's interface to generate evidence network diagrams, forest plots, league tables of pairwise comparisons, probability plots (rankograms), and inconsistency plots within Microsoft Excel. All figures generated are publication quality, thereby increasing the efficiency of knowledge transfer and manuscript preparation. We demonstrate the application of NetMetaXL using data from a network meta-analysis published previously which compares combined resynchronization and implantable defibrillator therapy in left ventricular dysfunction. We replicate results from the previous publication while demonstrating result summaries generated by the software. Use of the freely available NetMetaXL successfully demonstrated its ability to make running network meta-analyses more accessible to novice WinBUGS users by allowing analyses to be conducted entirely within Microsoft Excel. NetMetaXL also allows for more efficient and transparent critical appraisal of network meta-analyses, enhanced standardization of reporting, and integration with health economic evaluations which are frequently Excel-based.

A Microsoft-Excel-based tool for running and critically appraising network meta-analyses—an overview and application of NetMetaXL

PubMed Central

2014-01-01

Background The use of network meta-analysis has increased dramatically in recent years. WinBUGS, a freely available Bayesian software package, has been the most widely used software package to conduct network meta-analyses. However, the learning curve for WinBUGS can be daunting, especially for new users. Furthermore, critical appraisal of network meta-analyses conducted in WinBUGS can be challenging given its limited data manipulation capabilities and the fact that generation of graphical output from network meta-analyses often relies on different software packages than the analyses themselves. Methods We developed a freely available Microsoft-Excel-based tool called NetMetaXL, programmed in Visual Basic for Applications, which provides an interface for conducting a Bayesian network meta-analysis using WinBUGS from within Microsoft Excel. . This tool allows the user to easily prepare and enter data, set model assumptions, and run the network meta-analysis, with results being automatically displayed in an Excel spreadsheet. It also contains macros that use NetMetaXL’s interface to generate evidence network diagrams, forest plots, league tables of pairwise comparisons, probability plots (rankograms), and inconsistency plots within Microsoft Excel. All figures generated are publication quality, thereby increasing the efficiency of knowledge transfer and manuscript preparation. Results We demonstrate the application of NetMetaXL using data from a network meta-analysis published previously which compares combined resynchronization and implantable defibrillator therapy in left ventricular dysfunction. We replicate results from the previous publication while demonstrating result summaries generated by the software. Conclusions Use of the freely available NetMetaXL successfully demonstrated its ability to make running network meta-analyses more accessible to novice WinBUGS users by allowing analyses to be conducted entirely within Microsoft Excel. NetMetaXL also allows for more efficient and transparent critical appraisal of network meta-analyses, enhanced standardization of reporting, and integration with health economic evaluations which are frequently Excel-based. PMID:25267416

Teaching Millennial Students

ERIC Educational Resources Information Center

Nikirk, Martin

2012-01-01

The "Millennial Generation" includes students enrolled in primary grades through high school. These students are also known as Digital Natives, Generation Why, the Net Generation, Generation Me, and i-Kids. The generation includes ages ranging from approximately 7 to 30. This is the generation who have always had technology integrated into their…

Assessment of the Electrification of the Road Transport Sector on Net System Emissions

NASA Astrophysics Data System (ADS)

Miller, James

As worldwide environmental consciousness grows, electric vehicles (EVs) are becoming more common and despite the incredible potential for emissions reduction, the net emissions of the power system supply side plus the transportation system are dependent on the generation matrix. Current EV charging patterns tend to correspond directly with the peak consumption hours and have the potential to increase demand sharply allowing for only a small penetration of Electric Vehicles. Using the National Household Travel Survey (NHTS) data a model is created for vehicle travel patterns using trip chaining. Charging schemes are modeled to include uncontrolled residential, uncontrolled residential/industrial charging, optimized charging and optimized charging with vehicle to grid discharging. A charging profile is then determined based upon the assumption that electric vehicles would directly replace a percentage of standard petroleum-fueled vehicles in a known system. Using the generation profile for the specified region, a unit commitment model is created to establish not only the generation dispatch, but also the net CO2 profile for variable EV penetrations and charging profiles. This model is then used to assess the impact of the electrification of the road transport sector on the system net emissions.

High resolution printing of charge

DOEpatents

Rogers, John; Park, Jang-Ung

2015-06-16

Provided are methods of printing a pattern of charge on a substrate surface, such as by electrohydrodynamic (e-jet) printing. The methods relate to providing a nozzle containing a printable fluid, providing a substrate having a substrate surface and generating from the nozzle an ejected printable fluid containing net charge. The ejected printable fluid containing net charge is directed to the substrate surface, wherein the net charge does not substantially degrade and the net charge retained on the substrate surface. Also provided are functional devices made by any of the disclosed methods.

Trading spaces: building three-dimensional nets from two-dimensional tilings

PubMed Central

Castle, Toen; Evans, Myfanwy E.; Hyde, Stephen T.; Ramsden, Stuart; Robins, Vanessa

2012-01-01

We construct some examples of finite and infinite crystalline three-dimensional nets derived from symmetric reticulations of homogeneous two-dimensional spaces: elliptic (S2), Euclidean (E2) and hyperbolic (H2) space. Those reticulations are edges and vertices of simple spherical, planar and hyperbolic tilings. We show that various projections of the simplest symmetric tilings of those spaces into three-dimensional Euclidean space lead to topologically and geometrically complex patterns, including multiple interwoven nets and tangled nets that are otherwise difficult to generate ab initio in three dimensions. PMID:24098839

Communicating with the Net Generation

DTIC Science & Technology

2011-03-11

rich , digitally constructed communication and information world.2 Although this generation is often referred to as Generation Y or Millennial...Generations at Work, Millenials at Work, http://www.generationsatwork. com /articles_millennials_at_work.php (accessed November 21, 2010). 31 Thomas

Earth observation based assessment of the water production and water consumption of Nile Basin agro-ecosystems

USGS Publications Warehouse

Bastiaanssen, Wim G.M.; Karimi, Poolad; Rebelo, Lisa-Maria; Duan, Zheng; Senay, Gabriel; Muthuwatte, Lal; Smakhtin, Vladimir

2014-01-01

The increasing competition for water resources requires a better understanding of flows, fluxes, stocks, and the services and benefits related to water consumption. This paper explains how public domain Earth Observation data based on Moderate Resolution Imaging Spectroradiometer (MODIS), Second Generation Meteosat (MSG), Tropical Rainfall Measurement Mission (TRMM) and various altimeter measurements can be used to estimate net water production (rainfall (P) > evapotranspiration (ET)) and net water consumption (ET > P) of Nile Basin agro-ecosystems. Rainfall data from TRMM and the Famine Early Warning System Network (FEWS-NET) RainFall Estimates (RFE) products were used in conjunction with actual evapotranspiration from the Operational Simplified Surface Energy Balance (SSEBop) and ETLook models. Water flows laterally between net water production and net water consumption areas as a result of runoff and withdrawals. This lateral flow between the 15 sub-basins of the Nile was estimated, and partitioned into stream flow and non-stream flow using the discharge data. A series of essential water metrics necessary for successful integrated water management are explained and computed. Net water withdrawal estimates (natural and humanly instigated) were assumed to be the difference between net rainfall (Pnet) and actual evapotranspiration (ET) and some first estimates of withdrawals—without flow meters—are provided. Groundwater-dependent ecosystems withdraw large volumes of groundwater, which exceed water withdrawals for the irrigation sector. There is a strong need for the development of more open-access Earth Observation databases, especially for information related to actual ET. The fluxes, flows and storage changes presented form the basis for a global framework to describe monthly and annual water accounts in ungauged river basins.

Leptogenesis from spin-gravity coupling following inflation.

PubMed

Mohanty, Subhendra; Prasanna, A R; Lambiase, G

2006-02-24

The energy levels of the left- and the right-handed neutrinos are split in the background of gravitational waves generated during inflation, which, in presence of lepton-number-violating interactions, gives rise to a net lepton asymmetry at equilibrium. Lepton number violation is achieved by the same dimension five operator which gives rise to neutrino masses after electroweak symmetry breaking. A net baryon asymmetry of the same magnitude can be generated from this lepton asymmetry by electroweak sphaleron processes.

Interval-level measurement with visual analogue scales in Internet-based research: VAS Generator.

PubMed

Reips, Ulf-Dietrich; Funke, Frederik

2008-08-01

The present article describes VAS Generator (www.vasgenerator.net), a free Web service for creating a wide range of visual analogue scales that can be used as measurement devices in Web surveys and Web experimentation, as well as for local computerized assessment. A step-by-step example for creating and implementing a visual analogue scale with visual feedback is given. VAS Generator and the scales it generates work independently of platforms and use the underlying languages HTML and JavaScript. Results from a validation study with 355 participants are reported and show that the scales generated with VAS Generator approximate an interval-scale level. In light of previous research on visual analogue versus categorical (e.g., radio button) scales in Internet-based research, we conclude that categorical scales only reach ordinal-scale level, and thus visual analogue scales are to be preferred whenever possible.

Concentrating Solar Power Projects - Ivanpah Solar Electric Generating

Science.gov Websites

Energy; Google Technology: Power tower Turbine Capacity: Net: 377.0 MW Gross: 392.0 MW Status Turbine Capacity (Gross): 392.0 MW Turbine Capacity (Net): 377.0 MW Turbine Manufacturer: Siemens SST-900

Ambulatory electronic medical record payback analysis 7 years after implementation in a tertiary care county medical system.

PubMed

Kaelber, David C; Miller, Vince; Fisher, Nancy; Schlesinger, Jim; Norris, Greg

2007-10-11

Electronic medical records (EMRs) are gaining increasing prominence in healthcare, however still have low market penetration. EMR implementation cost is a primary perceived barrier. Here we present a payback analysis on an outpatient EMR implementation, showing capital expense recovery (net of operating costs) at 6 years and now generating $6 million yearly in direct savings for our healthcare system.

Cooperative processing user interfaces for AdaNET

NASA Technical Reports Server (NTRS)

Gutzmann, Kurt M.

1991-01-01

A cooperative processing user interface (CUI) system shares the task of graphical display generation and presentation between the user's computer and a remote host. The communications link between the two computers is typically a modem or Ethernet. The two main purposes of a CUI are reduction of the amount of data transmitted between user and host machines, and provision of a graphical user interface system to make the system easier to use.

Learning the ropes at Richard B. Russell Dam: Net systems for medium head hydropower pumpback and generation fish sampling

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schilt, C.R.; Vu, P.D.; Nestler, J.M.

1995-12-31

At Richard B. Russell Dam on the Savannah River we have been monitoring the magnitude (numbers and masses) and species compositions as well as possible survival of fish entrained in operation of four 85 MW Francis pump turbines. In this paper we review our progress in net design for hydropower application. We also discuss basic net handling and introduce a method for net management in a very turbulent tailrace. This report is meant to share what we have learned at Russell Dam in hopes that it will facilitate similar efforts elsewhere. The commercial fishing industry has evolved methods of netmore » construction and handling that may be applied, with appropriate modification, at dams. The nets we use are most appropriately called trawls in that they have the form of a long sock placed over the penstock or draft tube. These nets are superficially similar to those used in commercial trawling for fish. Important differences are that: (1) the net remains relatively stationary while the water moves through it, not vice versa; (2) water velocities and turbulence are much greater at dams than in commercial fishing operations and (3) mesh sizes are much smaller for environmental sampling than for commercial trawling. And while a fouled trawl may stop the boat that pulls it, the water passed in generation or pumpback (about 140 ft. head at Russell) is for all practical purposes unstoppable. Our nets fish in a very turbulent discharge at 7,000 cu. ft./sec/turbine. Their strength and their ability to pass water effectively under all possible operating conditions are primary concerns. Trawl length, mesh sizes, and hanging ratios are important factors. Although we have had setbacks (usually in the form of torn nets) as this study has developed, we have incrementally improved our net design and handling. We review our net failures and the solutions we have found thus far in both construction and handling.« less

Teaching STEM to Millennial Students

ERIC Educational Resources Information Center

Nikirk, Martin

2012-01-01

The "Millennial Generation" includes students enrolled in primary grades through high school. These students are also known as Digital Natives, Generation Why, the Net Generation, Generation Me, and i-Kids. The generation includes ages ranging from approximately 7 to 30. This is the generation who have always had technology integrated into their…

Modification of impulse generation during piqué turns with increased rotational demands.

PubMed

Zaferiou, Antonia M; Wilcox, Rand R; McNitt-Gray, Jill L

2016-06-01

During initiation of a piqué turn, a dancer generates impulse to achieve the desired lateral translation and whole-body rotation. The goal of this study was to determine how individuals regulate impulse generation when initiating piqué turns with increased rotational demands. Skilled dancers (n=10) performed single (∼360°) and double (∼720°) piqué turns from a stationary position. Linear and angular impulse generated by the push and turn legs were quantified using ground reaction forces and compared across turn conditions as a group and within a dancer using probability-based statistical methods. The results indicate that as the rotation demands of the piqué turn increased, the net angular impulse generated increased whereas net lateral impulse decreased. Early during turn initiation, the free moment contributed to angular impulse generation. Later during turn initiation, horizontal reaction forces were controlled to generate angular impulse. As rotational demands increased, the moment applied increased primarily from redirection of the horizontal reaction force (RFh) at the push leg and a combination of RFh magnitude and moment arm increases at the turn leg. RFh at each leg were coordinated to limit unwanted net linear impulse. Knowledge of observed subject-specific mechanisms is important to inform the design of turning performance training tools. Copyright © 2016 Elsevier B.V. All rights reserved.

Interactive Model Visualization for NET-VISA

NASA Astrophysics Data System (ADS)

Kuzma, H. A.; Arora, N. S.

2013-12-01

NET-VISA is a probabilistic system developed for seismic network processing of data measured on the International Monitoring System (IMS) of the Comprehensive nuclear Test Ban Treaty Organization (CTBTO). NET-VISA is composed of a Generative Model (GM) and an Inference Algorithm (IA). The GM is an explicit mathematical description of the relationships between various factors in seismic network analysis. Some of the relationships inside the GM are deterministic and some are statistical. Statistical relationships are described by probability distributions, the exact parameters of which (such as mean and standard deviation) are found by training NET-VISA using recent data. The IA uses the GM to evaluate the probability of various events and associations, searching for the seismic bulletin which has the highest overall probability and is consistent with a given set of measured arrivals. An Interactive Model Visualization tool (IMV) has been developed which makes 'peeking into' the GM simple and intuitive through a web-based interfaced. For example, it is now possible to access the probability distributions for attributes of events and arrivals such as the detection rate for each station for each of 14 phases. It also clarifies the assumptions and prior knowledge that are incorporated into NET-VISA's event determination. When NET-VISA is retrained, the IMV will be a visual tool for quality control both as a means of testing that the training has been accomplished correctly and that the IMS network has not changed unexpectedly. A preview of the IMV will be shown at this poster presentation. Homepage for the IMV IMV shows current model file and reference image.

Predicting multicellular function through multi-layer tissue networks

PubMed Central

Zitnik, Marinka; Leskovec, Jure

2017-01-01

Abstract Motivation: Understanding functions of proteins in specific human tissues is essential for insights into disease diagnostics and therapeutics, yet prediction of tissue-specific cellular function remains a critical challenge for biomedicine. Results: Here, we present OhmNet, a hierarchy-aware unsupervised node feature learning approach for multi-layer networks. We build a multi-layer network, where each layer represents molecular interactions in a different human tissue. OhmNet then automatically learns a mapping of proteins, represented as nodes, to a neural embedding-based low-dimensional space of features. OhmNet encourages sharing of similar features among proteins with similar network neighborhoods and among proteins activated in similar tissues. The algorithm generalizes prior work, which generally ignores relationships between tissues, by modeling tissue organization with a rich multiscale tissue hierarchy. We use OhmNet to study multicellular function in a multi-layer protein interaction network of 107 human tissues. In 48 tissues with known tissue-specific cellular functions, OhmNet provides more accurate predictions of cellular function than alternative approaches, and also generates more accurate hypotheses about tissue-specific protein actions. We show that taking into account the tissue hierarchy leads to improved predictive power. Remarkably, we also demonstrate that it is possible to leverage the tissue hierarchy in order to effectively transfer cellular functions to a functionally uncharacterized tissue. Overall, OhmNet moves from flat networks to multiscale models able to predict a range of phenotypes spanning cellular subsystems. Availability and implementation: Source code and datasets are available at http://snap.stanford.edu/ohmnet. Contact: jure@cs.stanford.edu PMID:28881986

Artificial neural network prediction of aircraft aeroelastic behavior

NASA Astrophysics Data System (ADS)

Pesonen, Urpo Juhani

An Artificial Neural Network that predicts aeroelastic behavior of aircraft is presented. The neural net was designed to predict the shape of a flexible wing in static flight conditions using results from a structural analysis and an aerodynamic analysis performed with traditional computational tools. To generate reliable training and testing data for the network, an aeroelastic analysis code using these tools as components was designed and validated. To demonstrate the advantages and reliability of Artificial Neural Networks, a network was also designed and trained to predict airfoil maximum lift at low Reynolds numbers where wind tunnel data was used for the training. Finally, a neural net was designed and trained to predict the static aeroelastic behavior of a wing without the need to iterate between the structural and aerodynamic solvers.

An Abstraction-Based Data Model for Information Retrieval

NASA Astrophysics Data System (ADS)

McAllister, Richard A.; Angryk, Rafal A.

Language ontologies provide an avenue for automated lexical analysis that may be used to supplement existing information retrieval methods. This paper presents a method of information retrieval that takes advantage of WordNet, a lexical database, to generate paths of abstraction, and uses them as the basis for an inverted index structure to be used in the retrieval of documents from an indexed corpus. We present this method as a entree to a line of research on using ontologies to perform word-sense disambiguation and improve the precision of existing information retrieval techniques.

Learning fuzzy information in a hybrid connectionist, symbolic model

NASA Technical Reports Server (NTRS)

Romaniuk, Steve G.; Hall, Lawrence O.

1993-01-01

An instance-based learning system is presented. SC-net is a fuzzy hybrid connectionist, symbolic learning system. It remembers some examples and makes groups of examples into exemplars. All real-valued attributes are represented as fuzzy sets. The network representation and learning method is described. To illustrate this approach to learning in fuzzy domains, an example of segmenting magnetic resonance images of the brain is discussed. Clearly, the boundaries between human tissues are ill-defined or fuzzy. Example fuzzy rules for recognition are generated. Segmentations are presented that provide results that radiologists find useful.

Characterization of NvLWamide-like neurons reveals stereotypy in Nematostella nerve net development.

PubMed

Havrilak, Jamie A; Faltine-Gonzalez, Dylan; Wen, Yiling; Fodera, Daniella; Simpson, Ayanna C; Magie, Craig R; Layden, Michael J

2017-11-15

The organization of cnidarian nerve nets is traditionally described as diffuse with randomly arranged neurites that show minimal reproducibility between animals. However, most observations of nerve nets are conducted using cross-reactive antibodies that broadly label neurons, which potentially masks stereotyped patterns produced by individual neuronal subtypes. Additionally, many cnidarians species have overt structures such as a nerve ring, suggesting higher levels of organization and stereotypy exist, but mechanisms that generated that stereotypy are unknown. We previously demonstrated that NvLWamide-like is expressed in a small subset of the Nematostella nerve net and speculated that observing a few neurons within the developing nerve net would provide a better indication of potential stereotypy. Here we document NvLWamide-like expression more systematically. NvLWamide-like is initially expressed in the typical neurogenic salt and pepper pattern within the ectoderm at the gastrula stage, and expression expands to include endodermal salt and pepper expression at the planula larval stage. Expression persists in both ectoderm and endoderm in adults. We characterized our NvLWamide-like::mCherry transgenic reporter line to visualize neural architecture and found that NvLWamide-like is expressed in six neural subtypes identifiable by neural morphology and location. Upon completing development the numbers of neurons in each neural subtype are minimally variable between animals and the projection patterns of each subtype are consistent. Furthermore, between the juvenile polyp and adult stages the number of neurons for each subtype increases. We conclude that development of the Nematostella nerve net is stereotyped between individuals. Our data also imply that one aspect of generating adult cnidarian nervous systems is to modify the basic structural architecture generated in the juvenile by increasing neural number proportionally with size. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

The Impacts of Changes to Nevada’s Net Metering Policy on the Financial Performance and Adoption of Distributed Photovoltaics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gagnon, Pieter; Sigrin, Ben; Gleason, Mike

Net energy metering (NEM) is a billing mechanism that has historically compensated owners of distributed generation systems at retail rates for any electricity that they export back to the grid rather than consume on-site. NEM can significantly enhance the financial performance of distributed generation systems from the owner’s perspective. The following analysis was designed to illustrate the potential impact of NEM policy and tariff changes implemented in early 2016 in Nevada.

Economics of a reduction in smoking: case study from Heartbeat Wales.

PubMed Central

Phillips, C J; Prowle, M J

1993-01-01

STUDY OBJECTIVE--This study aims to apply economic principles and techniques in evaluating a health promotion programme. DESIGN--This study is an economic appraisal of the Heartbeat Wales no smoking intervention programme. The costs incurred over the four year period 1985-89 have been identified and estimates have been made of the likely future impact of the reduced smoking prevalence within Wales in terms of reduced morbidity and displaced mortality in three disease groups--coronary heart disease, lung cancer, and chronic bronchitis. SETTING--Wales, UK. RESULTS--The net present value of benefits is considerably greater than costs in terms of both the NHS and the economy as a whole in Wales. In addition, the net costs per life year saved shows that the programme generates additional working life years at relatively low cost. Because not all the benefits can be fully attributed to the programme 'impact rates' ranging from 100 to 10% have been applied to the level of benefits. The evidence suggests that even if only 10% of the benefits could be attributed to the programme there is still a positive net present value of benefits. The relative efficiency of this programme has not been considered here. CONCLUSION--Large scale benefits to the NHS and the economy as a whole can be derived from reductions in smoking. PMID:8350035

Fine-Scale Event Location and Error Analysis in NET-VISA

NASA Astrophysics Data System (ADS)

Arora, N. S.; Russell, S.

2016-12-01

NET-VISA is a generative probabilistic model for the occurrence of seismic, hydro, and atmospheric events, and the propagation of energy from these events through various mediums and phases before being detected, or misdetected, by IMS stations. It is built on top of the basic station, and arrival detection processing at the IDC, and is currently being tested in the IDC network processing pipelines. A key distinguishing feature of NET-VISA is that it is easy to incorporate prior scientific knowledge and historical data into the probabilistic model. The model accounts for both detections and mis-detections when forming events, and this allows it to make more accurate event hypothesis. It has been continuously evaluated since 2012, and in each year it makes a roughly 60% reduction in the number of missed events without increasing the false event rate as compared to the existing GA algorithm. More importantly the model finds large numbers of events that have been confirmed by regional seismic bulletins but missed by the IDC analysts using the same data. In this work we focus on enhancements to the model to improve the location accuracy, and error ellipses. We will present a new version of the model that focuses on the fine scale around the event location, and present error ellipses and analysis of recent important events.

KM3NeT

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jong, M. de; Leiden Institute of Physics, Leiden University, Leiden; Collaboration: KM3NeT Collaboration

2015-07-15

KM3NeT is a large research infrastructure, that will consist of a network of deep-sea neutrino telescopes in the Mediterranean Sea. The main objective of KM3NeT is the discovery and subsequent observation of high-energy neutrino sources in the Universe. A further physics perspective is the measurement of the mass hierarchy of neutrinos. A corresponding study, ORCA, is ongoing within KM3NeT. A cost effective technology for (very) large water Cherenkov detectors has been developed based on a new generation of low price 3-inch photo-multiplier tubes. Following the successful deployment and operation of two prototypes, the construction of the KM3NeT research infrastructure hasmore » started. The prospects of the different phases of the implementation of KM3NeT are summarised.« less

KM3NeT

NASA Astrophysics Data System (ADS)

de Jong, M.

2015-07-01

KM3NeT is a large research infrastructure, that will consist of a network of deep-sea neutrino telescopes in the Mediterranean Sea. The main objective of KM3NeT is the discovery and subsequent observation of high-energy neutrino sources in the Universe. A further physics perspective is the measurement of the mass hierarchy of neutrinos. A corresponding study, ORCA, is ongoing within KM3NeT. A cost effective technology for (very) large water Cherenkov detectors has been developed based on a new generation of low price 3-inch photo-multiplier tubes. Following the successful deployment and operation of two prototypes, the construction of the KM3NeT research infrastructure has started. The prospects of the different phases of the implementation of KM3NeT are summarised.

Proximal tubule-specific glutamine synthetase deletion alters basal and acidosis-stimulated ammonia metabolism

PubMed Central

Lee, Hyun-Wook; Osis, Gunars; Handlogten, Mary E.; Lamers, Wouter H.; Chaudhry, Farrukh A.; Verlander, Jill W.

2016-01-01

Glutamine synthetase (GS) catalyzes the recycling of NH4+ with glutamate to form glutamine. GS is highly expressed in the renal proximal tubule (PT), suggesting ammonia recycling via GS could decrease net ammoniagenesis and thereby limit ammonia available for net acid excretion. The purpose of the present study was to determine the role of PT GS in ammonia metabolism under basal conditions and during metabolic acidosis. We generated mice with PT-specific GS deletion (PT-GS-KO) using Cre-loxP techniques. Under basal conditions, PT-GS-KO increased urinary ammonia excretion significantly. Increased ammonia excretion occurred despite decreased expression of key proteins involved in renal ammonia generation. After the induction of metabolic acidosis, the ability to increase ammonia excretion was impaired significantly by PT-GS-KO. The blunted increase in ammonia excretion occurred despite greater expression of multiple components of ammonia generation, including SN1 (Slc38a3), phosphate-dependent glutaminase, phosphoenolpyruvate carboxykinase, and Na+-coupled electrogenic bicarbonate cotransporter. We conclude that 1) GS-mediated ammonia recycling in the PT contributes to both basal and acidosis-stimulated ammonia metabolism and 2) adaptive changes in other proteins involved in ammonia metabolism occur in response to PT-GS-KO and cause an underestimation of the role of PT GS expression. PMID:27009341

Visualizing the spinal neuronal dynamics of locomotion

NASA Astrophysics Data System (ADS)

Subramanian, Kalpathi R.; Bashor, D. P.; Miller, M. T.; Foster, J. A.

2004-06-01

Modern imaging and simulation techniques have enhanced system-level understanding of neural function. In this article, we present an application of interactive visualization to understanding neuronal dynamics causing locomotion of a single hip joint, based on pattern generator output of the spinal cord. Our earlier work visualized cell-level responses of multiple neuronal populations. However, the spatial relationships were abstract, making communication with colleagues difficult. We propose two approaches to overcome this: (1) building a 3D anatomical model of the spinal cord with neurons distributed inside, animated by the simulation and (2) adding limb movements predicted by neuronal activity. The new system was tested using a cat walking central pattern generator driving a pair of opposed spinal motoneuron pools. Output of opposing motoneuron pools was combined into a single metric, called "Net Neural Drive", which generated angular limb movement in proportion to its magnitude. Net neural drive constitutes a new description of limb movement control. The combination of spatial and temporal information in the visualizations elegantly conveys the neural activity of the output elements (motoneurons), as well as the resulting movement. The new system encompasses five biological levels of organization from ion channels to observed behavior. The system is easily scalable, and provides an efficient interactive platform for rapid hypothesis testing.

X3D-Earth: Full Globe Coverage Utilizing Multiple Dataset

DTIC Science & Technology

2010-09-01

DtedNvtProcessor Class ..................................................128 Figure 63. Subversion Checkout in Netbeans ...to the Ant build.xml file within a NetBeans Project: <target name=“moveToHamming” depends=““> <scp todir=“user@hamming.uc.nps.edu:/work/user/DTED...This task was generated using the NetBeans IDE (can be downloaded at www.netbeans.org). The task was then executed within NetBeans . This type of

MECHANISMS OF FLUID SHEAR-INDUCED INHIBITION OF POPULATION GROWTH IN A RED-TIDE DINOFLAGELLATE

EPA Science Inventory

Net population growth of some dinoflagellates is inhibited by fluid shear at shear stresses comparable with those generated during oceanic turbulence. Decreased net growth may occur through lowered cell division, increased mortality, or both. The dominant mechanism under various ...

Planning and Implementing a Hospital Recycling Program at Naval Hospital, Camp Pendleton, California

DTIC Science & Technology

1992-08-01

communities have refused to license incinerators, saying "not in my back yard!" Recycling is quick, it’s economical, it can save natural resources, and...total costs - total credits) 4. Net Savings <Costs>: Present disposal Net recycling Net savings costs program costs <costs> * Assign only a...RECYCLING PROGRAM COSTS $ 9,739 (total costs - total credits) 4. Net Savings <Costs>: $ 9.287 _ $ 9.739 - S > Present disposal Net recycling Net

Net Resource Assessment (NetRA): A Collaborative Effort Between USGS Science and Decisions Center, the Science Impact Laboratory for Policy and Economics (University of New Mexico) and Sandia National Laboratory

NASA Astrophysics Data System (ADS)

Brookshire, D.; Bernknopf, R.; Adhikari, D. R.; Babis, C.; Broadbent, C. D.; Tidwell, V. C.

2015-12-01

Department of Interior Secretarial Order No. 3330, "… establishes a Department-wide mitigation strategy that will ensure consistency and efficiency in the review and permitting of infrastructure development projects and in conserving our Nation's valuable natural and cultural resources." The USGS Organic Act authorizes resource assessments to estimate the in-place potential capacity of energy, mineral, hydrologic, and biologic resources (20 Stat. 394; 43 U.S.C. 31) and later amendments. These two statements form the basis for the development of the Net Resources Assessment (NetRA) framework. NetRA is a policy-relevant, interdisciplinary approach to assessing natural resources availability in examining the regional-scale interrelationships between energy or mineral extraction and impact on ecosystem services. The systems dynamics approach (SD) emphasizes the interdependence of natural resource development and its effect on collocated ecosystem services over space and time. The example of the NetRA that will be presented focuses on tradeoffs associated with land management decisions in the West. The Piceance Basin, CO example that will be discussed involves development of a continuous gas deposit and its impact on Mule Deer and water quality. The SD is the hub for generating a range of simulated landscape outcomes. The probabilistic model provides an economic indicator as to the expected net societal benefit of economic development and biophysical indicators for ecosystem services affected in the region. Both natural and economic indicators are associated with each outcome via a tradeoff analysis the can be used for risk analysis. The NetRA also retains map attributes for before and after map comparisons to specific alternatives for an existing baseline. The model has three stages: map-based scenario development with slider bars (choice variables), side-by-side extraction and ecosystem services sub-models, and integrated multiple resource trade-off outcomes.

Classical ROS-dependent and early/rapid ROS-independent release of Neutrophil Extracellular Traps triggered by Leishmania parasites.

PubMed

Rochael, Natalia C; Guimarães-Costa, Anderson B; Nascimento, Michelle T C; DeSouza-Vieira, Thiago S; Oliveira, Matheus P; Garcia e Souza, Luiz F; Oliveira, Marcus F; Saraiva, Elvira M

2015-12-17

Neutrophil extracellular traps (NETs) extruded from neutrophils upon activation are composed of chromatin associated with cytosolic and granular proteins, which ensnare and kill microorganisms. This microbicidal mechanism named classical netosis has been shown to dependent on reactive oxygen species (ROS) generation by NADPH oxidase and also chromatin decondensation dependent upon the enzymes (PAD4), neutrophil elastase (NE) and myeloperoxidase (MPO). NET release also occurs through an early/rapid ROS-independent mechanism, named early/rapid vital netosis. Here we analyze the role of ROS, NE, MPO and PAD4 in the netosis stimulated by Leishmania amazonensis promastigotes in human neutrophils. We demonstrate that promastigotes induce a classical netosis, dependent on the cellular redox imbalance, as well as by a chloroamidine sensitive and elastase activity mechanism. Additionally, Leishmania also induces the early/rapid NET release occurring only 10 minutes after neutrophil-parasite interaction. We demonstrate here, that this early/rapid mechanism is dependent on elastase activity, but independent of ROS generation and chloroamidine. A better understanding of both mechanisms of NET release, and the NETs effects on the host immune system modulation, could support the development of new potential therapeutic strategies for leishmaniasis.

DO-increasing effects of a microscopic bubble generating system in a fish farm.

PubMed

Endo, Akira; Srithongouthai, Sarawut; Nashiki, Hisatsune; Teshiba, Ichiro; Iwasaki, Takaaki; Hama, Daigo; Tsutsumi, Hiroaki

2008-01-01

We have developed a "microscopic bubble generating system for the fish farm" and evaluated its ability to improve the quality of seawater and costs of it in marine cages of red sea bream (Pagrus major) in Kusuura Bay, Japan. Our results revealed that DO concentration of bubbling net pens increased and became significantly higher than the level outside the net pen (between 0.52 and 0.87 mg/L), and the whole water column was nearly saturated. Temperatures of the bubbling net pens decreased slightly between 0.08 and 0.12 degrees C in all the layers. Furthermore, micro-bubbles seemed to reach the deeper water due to the downward flow and diffusion. This study demonstrated that the microscopic bubble generating system developed in our research project could increase efficiently the dissolved oxygen concentration throughout all water layers of the fish farm. A capital and operation costs of the system is recoverable within a year.

Neutrophil extracellular traps in vasculitis, friend or foe?

PubMed

Söderberg, Daniel; Segelmark, Mårten

2018-01-01

Neutrophil extracellular traps (NETs) can be found at the sites of vascular lesions and in the circulation of patients with active small vessel vasculitis. Neutrophils from vasculitis patients release more NETs in vitro, and NETs have properties that can harm the vasculature both directly and indirectly. There are several ways to interfere with NET formation, which open for new therapeutic options. However, there are several types of NETs and different mechanisms of NET formation, and these might have different effects on inflammation. Here we review recent findings regarding the pathogenesis and therapeutic potentials of NETs in vasculitis. Experimental mouse models support a role for NETs in promoting vascular damage, where histones and mitochondrial DNA appear to be driving forces. Impaired formation of NETs, however, in an SLE-like mouse model leads to more severe disease, suggesting that NETs can be important in limiting inflammation. Studies on drug-induced vasculitis reveal that levamisole can induce NETosis via muscarinic receptors, predisposing for the generation of autoantibodies, including antineutrophil cytoplasmic autoantibodies (ANCA). This supports the notion that NETs can bridge the innate and adaptive immune systems. NETs can participate in the pathogenesis of vasculitis, but in some models there also seem to be protective effects of NETs. This complexity needs further evaluation with experimental models that are as specific as possible for human primary vasculitis.

Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation

PubMed Central

Yost, Christian C.; Schwertz, Hansjörg; Cody, Mark J.; Wallace, Jared A.; Campbell, Robert A.; Vieira-de-Abreu, Adriana; Araujo, Claudia V.; Schubert, Sebastian; Harris, Estelle S.; Rowley, Jesse W.; Rondina, Matthew T.; Koening, Curry L.; Weyrich, Andrew S.; Zimmerman, Guy A.

2016-01-01

Neutrophil granulocytes, also called polymorphonuclear leukocytes (PMNs), extrude molecular lattices of decondensed chromatin studded with histones, granule enzymes, and antimicrobial peptides that are referred to as neutrophil extracellular traps (NETs). NETs capture and contain bacteria, viruses, and other pathogens. Nevertheless, experimental evidence indicates that NETs also cause inflammatory vascular and tissue damage, suggesting that identifying pathways that inhibit NET formation may have therapeutic implications. Here, we determined that neonatal NET-inhibitory factor (nNIF) is an inhibitor of NET formation in umbilical cord blood. In human neonatal and adult neutrophils, nNIF inhibits key terminal events in NET formation, including peptidyl arginine deiminase 4 (PAD4) activity, neutrophil nuclear histone citrullination, and nuclear decondensation. We also identified additional nNIF-related peptides (NRPs) that inhibit NET formation. nNIFs and NRPs blocked NET formation induced by pathogens, microbial toxins, and pharmacologic agonists in vitro and in mouse models of infection and systemic inflammation, and they improved mortality in murine models of systemic inflammation, which are associated with NET-induced collateral tissue injury. The identification of NRPs as neutrophil modulators that selectively interrupt NET generation at critical steps suggests their potential as therapeutic agents. Furthermore, our results indicate that nNIF may be an important regulator of NET formation in fetal and neonatal inflammation. PMID:27599294

Disk MHD generator study

NASA Technical Reports Server (NTRS)

Retallick, F. D.

1980-01-01

Directly-fired, separately-fired, and oxygen-augmented MHD power plants incorporating a disk geometry for the MHD generator were studied. The base parameters defined for four near-optimum-performance MHD steam power systems of various types are presented. The finally selected systems consisted of (1) two directly fired cases, one at 1920 K (2996F) preheat and the other at 1650 K (2500 F) preheat, (2) a separately-fired case where the air is preheated to the same level as the higher temperature directly-fired cases, and (3) an oxygen augmented case with the same generator inlet temperature of 2839 (4650F) as the high temperature directly-fired and separately-fired cases. Supersonic Mach numbers at the generator inlet, gas inlet swirl, and constant Hall field operation were specified based on disk generator optimization. System pressures were based on optimization of MHD net power. Supercritical reheat stream plants were used in all cases. Open and closed cycle component costs are summarized and compared.

The impact of rotavirus vaccination on discounted net tax revenue in Egypt: a government perspective analysis.

PubMed

Connolly, Mark P; Topachevskyi, Oleksandr; Standaert, Baudouin; Ortega, Omayra; Postma, Maarten

2012-08-01

We evaluated national rotavirus (RV) immunization programme costs to estimate how resulting changes in morbidity and mortality will influence government fiscal accounts over time. The assumption was that increased childhood survival in vaccinated cohorts leads to increased numbers of children consuming government resource, and an increased number of future tax payers. Our objective was to evaluate the difference in lifetime discounted net tax revenue generated by RV vaccinated and unvaccinated cohorts from the Egyptian government perspective. The model framework adopts the Egyptian government perspective for RV immunization costs (year 2009 values) and all government transfers (e.g. education costs, health costs, pensions). To reflect the government tax revenue, we applied a fixed income tax burden to earnings over the lifetime of vaccinated and unvaccinated cohorts. At each year of the model, we derive net taxes (gross taxes less transfers) discounted to the immunization year to reflect the present value of RV vaccination investment costs. Projected incremental net present values of the vaccinated cohort versus the unvaccinated cohort are $US6.1 million, $US58.1 million and $US55.7 million at 25-, 50- and 72-year time horizons, respectively. The internal rate of return for the government based on RV vaccination at years 25, 50 and 72 was 10.8%, 15.1% and 14.9, respectively. Within the first 5 years of vaccination, 76% of vaccine acquisition costs were offset due to direct and indirect cost savings attributed to a reduction in RV-related disease burden. Investments in RV vaccination in a single year are entirely offset when the vaccinated cohort of newborns reach 22 years of age. The government perspective is useful for evaluating investments in RV vaccination because of ongoing government transfers and tax receipts attributed to changes in RV-attributed morbidity and mortality. The analysis described here illustrates that investing in RV offers tangible long-term fiscal benefits for government over many generations that would not ordinarily be captured in economic evaluations typically applied to healthcare interventions.

Electric power quarterly, July--September 1988

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1989-01-19

The Electric Power Quarterly (EPQ) is prepared by the Electric Power Division; Office of Coal, Nuclear, Electric and Alternate Fuels; Energy Information Administration (EIA). The EPQ is designed to provide energy decisionmakers with accurate and timely generation and fuel cost and quality information on a plant-by-plant basis. This publication is designed for applications by electric utilities, fuel suppliers, consumers, educational institutions, and government in recognition of the importance of energy planning. The EPQ presents monthly summaries of electric utility statistics at the national, Census division, state, company, and plant levels on the following subjects: quantity of fuel; cost of fuel;more » quality of fuel; net generation; fuel consumption, and fuel stocks. In addition, the EPQ presents a quarterly summary of reported major disturbances and unusual occurrences. 1 fig., 15 tabs.« less

New tool to assemble repetitive regions using next-generation sequencing data

NASA Astrophysics Data System (ADS)

Kuśmirek, Wiktor; Nowak, Robert M.; Neumann, Łukasz

2017-08-01

The next generation sequencing techniques produce a large amount of sequencing data. Some part of the genome are composed of repetitive DNA sequences, which are very problematic for the existing genome assemblers. We propose a modification of the algorithm for a DNA assembly, which uses the relative frequency of reads to properly reconstruct repetitive sequences. The new approach was implemented and tested, as a demonstration of the capability of our software we present some results for model organisms. The new implementation, using a three-layer software architecture was selected, where the presentation layer, data processing layer, and data storage layer were kept separate. Source code as well as demo application with web interface and the additional data are available at project web-page: http://dnaasm.sourceforge.net.

17 CFR 240.16a-1 - Definition of terms.

Code of Federal Regulations, 2014 CFR

2014-04-01

..., investment adviser, investment manager, trustee or person or entity performing a similar function; provided... when payable, is calculated based upon net capital gains and/or net capital appreciation generated from... issuer in charge of a principal business unit, division or function (such as sales, administration or...

17 CFR 240.16a-1 - Definition of terms.

Code of Federal Regulations, 2013 CFR

2013-04-01

..., investment adviser, investment manager, trustee or person or entity performing a similar function; provided... when payable, is calculated based upon net capital gains and/or net capital appreciation generated from... issuer in charge of a principal business unit, division or function (such as sales, administration or...

Implementation of control point form of algebraic grid-generation technique

NASA Technical Reports Server (NTRS)

Choo, Yung K.; Miller, David P.; Reno, Charles J.

1991-01-01

The control point form (CPF) provides explicit control of physical grid shape and grid spacing through the movement of the control points. The control point array, called a control net, is a space grid type arrangement of locations in physical space with an index for each direction. As an algebraic method CPF is efficient and works well with interactive computer graphics. A family of menu-driven, interactive grid-generation computer codes (TURBO) is being developed by using CPF. Key features of TurboI (a TURBO member) are discussed and typical results are presented. TurboI runs on any IRIS 4D series workstation.

The Integration of Gasification Systems with Gas Engine to Produce Electrical Energy from Biomass

NASA Astrophysics Data System (ADS)

Siregar, K.; Alamsyah, R.; Ichwana; Sholihati; Tou, S. B.; Siregar, N. C.

2018-05-01

The need for energy especially biomass-based renewable energy continues to increase in Indonesia. The objective of this research was to design downdraft gasifier machine with high content of combustible gas on gas engine. Downdraft gasifier machine was adjusted with the synthetic gas produced from biomass. Besides that, the net energy ratio, net energy balance, renewable index, economic analysis, and impact assessment also been conducted. Gas engine that was designed in this research had been installed with capacity of 25 kW with diameter and height of reactor were 900 mm and 1000 mm respectively. The method used here were the design the Detailed Engineering Design (DED), assembly, and performance test of gas engine. The result showed that gas engine for biomass can be operated for 8 hours with performance engine of 84% and capacity of 25 kW. Net energy balance, net energy ratio, and renewable index was 30 MJ/kWh-electric; 0.89; 0.76 respectively. The value of GHG emission of Biomass Power Generation is 0.03 kg-CO2eq/MJ. Electrical production cost for Biomass Power Generation is about Rp.1.500,/kWh which is cheaper than Solar Power Generation which is about of Rp. 3.300,-/kWh.

Relocation of net-acid-generating waste to improve post-mining water chemistry.

PubMed

Morin, K A; Hutt, N M

2001-01-01

Acidic drainage and metal leaching are long-term environmental liabilities that can persist for many decades to millennia. One technique to improve the water chemistry and ecology of post-mining landscapes is to relocate and submerge net-acid-generating mine materials in a lake or water-retaining impoundment. One example of a carefully executed relocation of waste rock took place at the Eskay Creek Mine in Canada. Pre-relocation studies included an empirical relationship that related (1) the amount of acidity retained by the waste rock during past oxidation to (2) the amount of lime needed in each truckload for neutralization of the acidity and for suppression of metal release. During relocation, thousands of rinse pH measurements indicated net acidity varied significantly over short distances within the waste rock and that acidic rock could not be reliably segregated from near-netural rock. After relocation, water from the watershed continued to be acidic for a few years, then returned to near-neutral pH and near-background concentrations of metals. The chemistry of the lake where the waste rock was submerged remains near background conditions. Therefore, with careful planning and implementation, the relocation and submergence of net-acid-generating materials can greatly improve post-mining water chemistry.

CNN-SVM for Microvascular Morphological Type Recognition with Data Augmentation.

PubMed

Xue, Di-Xiu; Zhang, Rong; Feng, Hui; Wang, Ya-Lei

2016-01-01

This paper focuses on the problem of feature extraction and the classification of microvascular morphological types to aid esophageal cancer detection. We present a patch-based system with a hybrid SVM model with data augmentation for intraepithelial papillary capillary loop recognition. A greedy patch-generating algorithm and a specialized CNN named NBI-Net are designed to extract hierarchical features from patches. We investigate a series of data augmentation techniques to progressively improve the prediction invariance of image scaling and rotation. For classifier boosting, SVM is used as an alternative to softmax to enhance generalization ability. The effectiveness of CNN feature representation ability is discussed for a set of widely used CNN models, including AlexNet, VGG-16, and GoogLeNet. Experiments are conducted on the NBI-ME dataset. The recognition rate is up to 92.74% on the patch level with data augmentation and classifier boosting. The results show that the combined CNN-SVM model beats models of traditional features with SVM as well as the original CNN with softmax. The synthesis results indicate that our system is able to assist clinical diagnosis to a certain extent.

Net-Centric Sensors and Data Sources (N-CSDS) GEODSS Sidecar

NASA Astrophysics Data System (ADS)

Richmond, D.

2012-09-01

Vast amounts of Space Situational Sensor data is collected each day on closed, legacy systems. Massachusetts Institute of Technology Lincoln Laboratory (MIT/LL) developed a Net-Centric approach to expose this data under the Extended Space Sensors Architecture (ESSA) Advanced Concept Technology Demonstration (ACTD). The Net-Centric Sensors and Data Sources (N-CSDS) Ground-based Electro Optical Deep Space Surveillance (GEODSS) Sidecar is the next generation that moves the ESSA ACTD engineering tools to an operational baseline. The N-CSDS GEODSS sidecar high level architecture will be presented, highlighting the features that supports deployment at multiple diverse sensor sites. Other key items that will be covered include: 1) The Web Browser interface to perform searches of historical data 2) The capabilities of the deployed Web Services and example service request/responses 3) Example data and potential user applications will be highlighted 4) Specifics regarding the process to gain access to the N-CSDS GEODSS sensor data in near real time 5) Current status and future deployment plans (Including plans for deployment to the Maui GEODSS Site)

Engine performance analysis and optimization of a dual-mode scramjet with varied inlet conditions

NASA Astrophysics Data System (ADS)

Tian, Lu; Chen, Li-Hong; Chen, Qiang; Zhong, Feng-Quan; Chang, Xin-Yu

2016-02-01

A dual-mode scramjet can operate in a wide range of flight conditions. Higher thrust can be generated by adopting suitable combustion modes. Based on the net thrust, an analysis and preliminary optimal design of a kerosene-fueled parameterized dual-mode scramjet at a crucial flight Mach number of 6 were investigated by using a modified quasi-one-dimensional method and simulated annealing strategy. Engine structure and heat release distributions, affecting the engine thrust, were chosen as analytical parameters for varied inlet conditions (isolator entrance Mach number: 1.5-3.5). Results show that different optimal heat release distributions and structural conditions can be obtained at five different inlet conditions. The highest net thrust of the parameterized dual-mode engine can be achieved by a subsonic combustion mode at an isolator entrance Mach number of 2.5. Additionally, the effects of heat release and scramjet structure on net thrust have been discussed. The present results and the developed analytical method can provide guidance for the design and optimization of high-performance dual-mode scramjets.

The balance of intergenerational family transfers: a life-cycle perspective.

PubMed

Mudrazija, Stipica

2014-09-01

The aim of this study is to determine the likelihood and net amount of parent-child transfers over the adult life cycle across European welfare regimes. The study introduces an economic life-cycle model of family transfers to describe the evolution of family exchanges across generations over time, which reveals a nonlinear relationship of age and net family transfers. Furthermore, it refines the method of estimating parent-child net transfers. Data come from the Survey of Health, Ageing, and Retirement in Europe, and include 36,095 parent-child dyads from 11 European countries representing social democratic, conservative, and traditional welfare-state regimes. The findings reveal net value of family intergenerational support follows a nonlinear pattern across the adult life cycle, with positive transfers from parents to adult children decreasing modestly until advanced old age when the decrease intensifies. Net family support benefits individuals and generations with larger relative need. The transition in the net family support pattern starts later and is less pronounced across social democratic welfare-regime countries while the opposite is true in traditional welfare-regime countries. These findings might be interpreted as being linked to differences in the public policies guaranteeing different levels of provision for dependent populations across different welfare regimes. They are consistent with a comparatively smaller role of family support in the intergenerational redistribution of resources in societies with larger public intergenerational support to dependent populations.

Enabling CCS via Low-temperature Geothermal Energy Integration for Fossil-fired Power Generation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davidson, Casie L.; Heldebrant, D. J.; Bearden, M. D.

Here, among the key barriers to commercial scale deployment is the cost associated with CO 2 capture. This is particularly true for existing large, fossil-fired assets that account for a large fraction of the electricity generation fleet in developed nations, including the U.S. Fitting conventional combustion technologies with CO 2 capture systems can carry an energy penalty of thirty percent or more, resulting in an increased price of power to the grid, as well as an overall decrease in net plant output. Taken together with the positive growth in demand for electricity, this implies a need for accelerated capital build-outmore » in the power generation markets to accommodate both demand growth and decreased output at retrofitted plants. In this paper, the authors present the results of a study to assess the potential to use geothermal energy to provide boiler feedwater preheating, capturing efficiency improvements designed to offset the losses associated with CO 2 capture. Based on NETL benchmark cases and subsequent analysis of the application using site-specific data from the North Valmy power plant, several cases for CO 2 capture were evaluated. These included geothermally assisted MEA capture, CO2BOLs capture, and stand-alone hybrid power generation, compared with a baseline, no-geothermal case. Based on Case 10, and assuming 2.7 MMlb/h of geothermally sourced 150 ºC water, the parasitic power load associated with MEA capture could be offset by roughly seven percent, resulting in a small (~1 percent) overall loss to net power generation, but at levelized costs of electricity similar to the no-geothermal CCS case. For the CO 2BOLs case, the availability of 150°C geothermal fluid could allow the facility to not only offset the net power decrease associated with CO 2BOLs capture alone, but could increase nameplate capacity by two percent. The geothermally coupled CO 2BOLs case also decreases LCOE by 0.75 ¢/kWh relative to the non-hybrid CO 2BOLs case, with the improved performance over the MEA case driven by the lower regeneration temperature and associated duty for CO 2BOLs relative to MEA.« less

Enabling CCS via Low-temperature Geothermal Energy Integration for Fossil-fired Power Generation

DOE PAGES

Davidson, Casie L.; Heldebrant, D. J.; Bearden, M. D.; ...

2017-08-18

Here, among the key barriers to commercial scale deployment is the cost associated with CO 2 capture. This is particularly true for existing large, fossil-fired assets that account for a large fraction of the electricity generation fleet in developed nations, including the U.S. Fitting conventional combustion technologies with CO 2 capture systems can carry an energy penalty of thirty percent or more, resulting in an increased price of power to the grid, as well as an overall decrease in net plant output. Taken together with the positive growth in demand for electricity, this implies a need for accelerated capital build-outmore » in the power generation markets to accommodate both demand growth and decreased output at retrofitted plants. In this paper, the authors present the results of a study to assess the potential to use geothermal energy to provide boiler feedwater preheating, capturing efficiency improvements designed to offset the losses associated with CO 2 capture. Based on NETL benchmark cases and subsequent analysis of the application using site-specific data from the North Valmy power plant, several cases for CO 2 capture were evaluated. These included geothermally assisted MEA capture, CO2BOLs capture, and stand-alone hybrid power generation, compared with a baseline, no-geothermal case. Based on Case 10, and assuming 2.7 MMlb/h of geothermally sourced 150 ºC water, the parasitic power load associated with MEA capture could be offset by roughly seven percent, resulting in a small (~1 percent) overall loss to net power generation, but at levelized costs of electricity similar to the no-geothermal CCS case. For the CO 2BOLs case, the availability of 150°C geothermal fluid could allow the facility to not only offset the net power decrease associated with CO 2BOLs capture alone, but could increase nameplate capacity by two percent. The geothermally coupled CO 2BOLs case also decreases LCOE by 0.75 ¢/kWh relative to the non-hybrid CO 2BOLs case, with the improved performance over the MEA case driven by the lower regeneration temperature and associated duty for CO 2BOLs relative to MEA.« less

Gene network inference by fusing data from diverse distributions

PubMed Central

Žitnik, Marinka; Zupan, Blaž

2015-01-01

Motivation: Markov networks are undirected graphical models that are widely used to infer relations between genes from experimental data. Their state-of-the-art inference procedures assume the data arise from a Gaussian distribution. High-throughput omics data, such as that from next generation sequencing, often violates this assumption. Furthermore, when collected data arise from multiple related but otherwise nonidentical distributions, their underlying networks are likely to have common features. New principled statistical approaches are needed that can deal with different data distributions and jointly consider collections of datasets. Results: We present FuseNet, a Markov network formulation that infers networks from a collection of nonidentically distributed datasets. Our approach is computationally efficient and general: given any number of distributions from an exponential family, FuseNet represents model parameters through shared latent factors that define neighborhoods of network nodes. In a simulation study, we demonstrate good predictive performance of FuseNet in comparison to several popular graphical models. We show its effectiveness in an application to breast cancer RNA-sequencing and somatic mutation data, a novel application of graphical models. Fusion of datasets offers substantial gains relative to inference of separate networks for each dataset. Our results demonstrate that network inference methods for non-Gaussian data can help in accurate modeling of the data generated by emergent high-throughput technologies. Availability and implementation: Source code is at https://github.com/marinkaz/fusenet. Contact: blaz.zupan@fri.uni-lj.si Supplementary information: Supplementary information is available at Bioinformatics online. PMID:26072487

Techno Economical Study of PV-Diesel Power System for a Remote Island in Indonesia : A Case Study of Miangas Island

NASA Astrophysics Data System (ADS)

Rumbayan, M.; Nagasaka, K.

2018-05-01

The purpose of this study is to conduct the techno economical study of PC-Diesel power system based on renewable energy available locally in a remote island. This research is a case study for Miangas island which is the border island between Indonesia and Philipines. It is located in Talaud Island regency of North Sulawesi province of Indonesia. The monthly average daily radiation in Miangas island is 5.52 kWh/m2.The research methods used are data collection and data analysis using software HOMER. Based on the simulation result, the techno economic study of PV-Diesel power plant system based on energy demand in Miangas island can be obtained. The Cost of Energy (COE), Net Present Cost (NPC) and operating cost for proposed hybrid PV-Diesel power generation can be assessed for the design power systems uses Canadian solar Max Power C56x-325P of 150 KW PV, 18 string of Surette 6CS25P, Diesel Generator 50 kW and converter Magnum MS4448PAE 25 kW. The annual electricity production from the PV Diesel system for Miangas island is 309.589 kWh in which 80.7% electricity comes from PV, 19.3% electricity comes from diesel with the 109.063 kWh excess electricity. The cost of generating electrical energy in the term of cost of energy (COE), Net Present Cost (NPC) and operating cost are 0.318 US/kWh, 719.673 US and 36.857 US respectively.

Delaware | Solar Research | NREL

Science.gov Websites

. Customer-generators interested in selling Solar Renewable Energy Credits (SRECs) into the Delaware spot periods starting on April 1st or October 1st as chosen by the customer. Net Metering Delaware modified the state net metering significantly in 2017, including expanding it to all customer classes, adding biogas

Mineralizing urban net-zero water treatment: Phase II field results and design recommendations

EPA Science Inventory

Net-zero water (NZW) systems, or water management systems achieving high recycling rates and low residuals generation so as to avoid water import and export, can also conserve energy used to heat and convey water, while economically restoring local eco-hydrology. However, design ...

47 CFR 32.4330 - Unamortized nonoperating investment tax credits-net.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false Unamortized nonoperating investment tax credits... Sheet Accounts § 32.4330 Unamortized nonoperating investment tax credits—net. (a) This account shall be credited and Account 7400, Nonoperating Taxes, shall be debited with investment tax credits generated from...

Feasibility Study of Food Waste Co-Digestion at U.S. Army Installations

EPA Science Inventory

Net Zero is a comprehensive approach to preserve natural resources by focusing on energy, water, and waste. Fort Huachuca, Arizona, is a strong advocate and participant in the Army Net Zero program. The Fort has installed energy saving and renewable energy generating systems, an...

Twin-spool turbopumps for ''low'' net positive suction pressure operations

NASA Technical Reports Server (NTRS)

Bair, E. K.; Campbell, W. E.; Ford, O. I.

1970-01-01

Modified single-shaft turbopump incorporates inducer and main pump, each separately driven at different speeds through coaxial-shaft arrangement. Inducer operates at low speed for low net positive suction pressure, main pump operates at high speed to generate high pressure. This arrangement requires no external control for the inducer.

Petri net controllers for distributed robotic systems

NASA Technical Reports Server (NTRS)

Lefebvre, D. R.; Saridis, George N.

1992-01-01

Petri nets are a well established modelling technique for analyzing parallel systems. When coupled with an event-driven operating system, Petri nets can provide an effective means for integrating and controlling the functions of distributed robotic applications. Recent work has shown that Petri net graphs can also serve as remarkably intuitive operator interfaces. In this paper, the advantages of using Petri nets as high-level controllers to coordinate robotic functions are outlined, the considerations for designing Petri net controllers are discussed, and simple Petri net structures for implementing an interface for operator supervision are presented. A detailed example is presented which illustrates these concepts for a sensor-based assembly application.

Net Metering Policy Development and Distributed Solar Generation in Minnesota: Overview of Trends in Nationwide Policy Development and Implications of Increasing the Eligible System Size Cap

DOE Office of Scientific and Technical Information (OSTI.GOV)

Doris, E.; Busche, S.; Hockett, S.

2009-12-01

The goal of the Minnesota net metering policy is to give the maximum possible encouragement to distributed generation assets, especially solar electric systems (MN 2008). However, according to a published set of best practices (NNEC 2008) that prioritize the maximum development of solar markets within states, the Minnesota policy does not incorporate many of the important best practices that may help other states transform their solar energy markets and increase the amount of grid-connected distributed solar generation assets. Reasons cited include the low system size limit of 40kW (the best practices document recommends a 2 MW limit) and a lackmore » of language protecting generators from additional utility fees. This study was conducted to compare Minnesota's policies to national best practices. It provides an overview of the current Minnesota policy in the context of these best practices and other jurisdictions' net metering policies, as well as a qualitative assessment of the impacts of raising the system size cap within the policy based on the experiences of other states.« less

[Relationships amongst work values, job characteristics and job involvement in "net generation" nurses].

PubMed

Chen, Sue-Hui; Chiou, Chii-Jun

2010-04-01

Children of the so-called "net generation" began joining the nurse workforce from the mid-1990s. Studies on the characteristics of this generation have been done primarily outside of Taiwan, and results may not adequately reflect conditions in Taiwan due to cultural differences. This study aimed to investigate the relationships amongst work values, job characteristics and job involvement in "net generation" nurses. This study employed a cross-sectional design. A randomized sample of 370 nurses born between 1977 and 1985 working in a medical center or a community hospital in Southern Taiwan accepted our invitation to join this study. A structured questionnaire was used to collect data. (1) Variables including work values, job characteristics, head nurse leadership qualities, job structure and opportunities for in-service education all correlated significantly with job involvement. (2) Regression analysis showed work values, job characteristics, head nurse leadership and religious belief to be significant predictors of job involvement, explaining 22.6% of the variance. This study provides insights that may be of potential value to nursing administrators. We suggest that administrators adopt democratic management practices, build diverse learning methods, strengthen autonomy, completeness, and feedback, and provide appropriate work guidance for nurses to increase job involvement.

Protein cross-linking by chlorinated polyamines and transglutamylation stabilizes neutrophil extracellular traps.

PubMed

Csomós, Krisztián; Kristóf, Endre; Jakob, Bernadett; Csomós, István; Kovács, György; Rotem, Omri; Hodrea, Judit; Bagoly, Zsuzsa; Muszbek, Laszlo; Balajthy, Zoltán; Csősz, Éva; Fésüs, László

2016-08-11

Neutrophil extracellular trap (NET) ejected from activated dying neutrophils is a highly ordered structure of DNA and selected proteins capable to eliminate pathogenic microorganisms. Biochemical determinants of the non-randomly formed stable NETs have not been revealed so far. Studying the formation of human NETs we have observed that polyamines were incorporated into the NET. Inhibition of myeloperoxidase, which is essential for NET formation and can generate reactive chlorinated polyamines through hypochlorous acid, decreased polyamine incorporation. Addition of exogenous primary amines that similarly to polyamines inhibit reactions catalyzed by the protein cross-linker transglutaminases (TGases) has similar effect. Proteomic analysis of the highly reproducible pattern of NET components revealed cross-linking of NET proteins through chlorinated polyamines and ɛ(γ-glutamyl)lysine as well as bis-γ-glutamyl polyamine bonds catalyzed by the TGases detected in neutrophils. Competitive inhibition of protein cross-linking by monoamines disturbed the cross-linking pattern of NET proteins, which resulted in the loss of the ordered structure of the NET and significantly reduced capacity to trap bacteria. Our findings provide explanation of how NETs are formed in a reproducible and ordered manner to efficiently neutralize microorganisms at the first defense line of the innate immune system.

Protein cross-linking by chlorinated polyamines and transglutamylation stabilizes neutrophil extracellular traps

PubMed Central

Csomós, Krisztián; Kristóf, Endre; Jakob, Bernadett; Csomós, István; Kovács, György; Rotem, Omri; Hodrea, Judit; Bagoly, Zsuzsa; Muszbek, Laszlo; Balajthy, Zoltán; Csősz, Éva; Fésüs, László

2016-01-01

Neutrophil extracellular trap (NET) ejected from activated dying neutrophils is a highly ordered structure of DNA and selected proteins capable to eliminate pathogenic microorganisms. Biochemical determinants of the non-randomly formed stable NETs have not been revealed so far. Studying the formation of human NETs we have observed that polyamines were incorporated into the NET. Inhibition of myeloperoxidase, which is essential for NET formation and can generate reactive chlorinated polyamines through hypochlorous acid, decreased polyamine incorporation. Addition of exogenous primary amines that similarly to polyamines inhibit reactions catalyzed by the protein cross-linker transglutaminases (TGases) has similar effect. Proteomic analysis of the highly reproducible pattern of NET components revealed cross-linking of NET proteins through chlorinated polyamines and ɛ(γ-glutamyl)lysine as well as bis-γ-glutamyl polyamine bonds catalyzed by the TGases detected in neutrophils. Competitive inhibition of protein cross-linking by monoamines disturbed the cross-linking pattern of NET proteins, which resulted in the loss of the ordered structure of the NET and significantly reduced capacity to trap bacteria. Our findings provide explanation of how NETs are formed in a reproducible and ordered manner to efficiently neutralize microorganisms at the first defense line of the innate immune system. PMID:27512953

Modeling and performance analysis of QoS data

NASA Astrophysics Data System (ADS)

Strzeciwilk, Dariusz; Zuberek, Włodzimierz M.

2016-09-01

The article presents the results of modeling and analysis of data transmission performance on systems that support quality of service. Models are designed and tested, taking into account multiservice network architecture, i.e. supporting the transmission of data related to different classes of traffic. Studied were mechanisms of traffic shaping systems, which are based on the Priority Queuing with an integrated source of data and the various sources of data that is generated. Discussed were the basic problems of the architecture supporting QoS and queuing systems. Designed and built were models based on Petri nets, supported by temporal logics. The use of simulation tools was to verify the mechanisms of shaping traffic with the applied queuing algorithms. It is shown that temporal models of Petri nets can be effectively used in the modeling and analysis of the performance of computer networks.

Energy assessment of second generation (2G) ethanol production from wheat straw in Indian scenario.

PubMed

Mishra, Archana; Kumar, Akash; Ghosh, Sanjoy

2018-03-01

Impact of second-generation ethanol (2G) use in transportation sector mainly depends upon energy efficiency of entire production process. The objective of present study was to determine energy efficiency of a potential lignocellulosic feedstock; wheat straw and its conversion into cellulosic ethanol in Indian scenario. Energy efficiency was determined by calculating Net energy ratio (NER), i.e. ratio of output energy obtained by ethanol and input energy used in ethanol production. Energy consumption and generation at each step is calculated briefly (11,837.35 MJ/ha during Indian dwarf irrigated variety of wheat crop production and 7.1148 MJ/kg straw during ethanol production stage). Total energy consumption is calculated as 8.2988 MJ/kg straw whereas energy generation from ethanol is 15.082 MJ/kg straw; resulting into NER > 1. Major portion of agricultural energy input is contributed by diesel and fertilisers whereas refining process of wheat straw feedstock to ethanol and by-products require mainly in the form of steam and electricity. On an average, 1671.8 kg water free ethanol, 930 kg lignin rich biomass (for combustion), and 561 kg C5-molasses (for fodder) per hectare are produced. Findings of this study, net energy ratio (1.81) and figure of merit (14.8028 MJ/nil kg carbon) proves wheat straw as highest energy efficient lignocellulosic feedstock for the country.

A Computational Methodology for Simulating Thermal Loss Testing of the Advanced Stirling Convertor

NASA Technical Reports Server (NTRS)

Reid, Terry V.; Wilson, Scott D.; Schifer, Nicholas A.; Briggs, Maxwell H.

2012-01-01

The U.S. Department of Energy (DOE) and Lockheed Martin Space Systems Company (LMSSC) have been developing the Advanced Stirling Radioisotope Generator (ASRG) for use as a power system for space science missions. This generator would use two highefficiency Advanced Stirling Convertors (ASCs), developed by Sunpower Inc. and NASA Glenn Research Center (GRC). The ASCs convert thermal energy from a radioisotope heat source into electricity. As part of ground testing of these ASCs, different operating conditions are used to simulate expected mission conditions. These conditions require achieving a particular operating frequency, hot end and cold end temperatures, and specified electrical power output for a given net heat input. In an effort to improve net heat input predictions, numerous tasks have been performed which provided a more accurate value for net heat input into the ASCs, including the use of multidimensional numerical models. Validation test hardware has also been used to provide a direct comparison of numerical results and validate the multi-dimensional numerical models used to predict convertor net heat input and efficiency. These validation tests were designed to simulate the temperature profile of an operating Stirling convertor and resulted in a measured net heat input of 244.4 W. The methodology was applied to the multi-dimensional numerical model which resulted in a net heat input of 240.3 W. The computational methodology resulted in a value of net heat input that was 1.7 percent less than that measured during laboratory testing. The resulting computational methodology and results are discussed.

PatterNet: a system to learn compact physical design pattern representations for pattern-based analytics

NASA Astrophysics Data System (ADS)

Lutich, Andrey

2017-07-01

This research considers the problem of generating compact vector representations of physical design patterns for analytics purposes in semiconductor patterning domain. PatterNet uses a deep artificial neural network to learn mapping of physical design patterns to a compact Euclidean hyperspace. Distances among mapped patterns in this space correspond to dissimilarities among patterns defined at the time of the network training. Once the mapping network has been trained, PatterNet embeddings can be used as feature vectors with standard machine learning algorithms, and pattern search, comparison, and clustering become trivial problems. PatterNet is inspired by the concepts developed within the framework of generative adversarial networks as well as the FaceNet. Our method facilitates a deep neural network (DNN) to learn directly the compact representation by supplying it with pairs of design patterns and dissimilarity among these patterns defined by a user. In the simplest case, the dissimilarity is represented by an area of the XOR of two patterns. Important to realize that our PatterNet approach is very different to the methods developed for deep learning on image data. In contrast to "conventional" pictures, the patterns in the CAD world are the lists of polygon vertex coordinates. The method solely relies on the promise of deep learning to discover internal structure of the incoming data and learn its hierarchical representations. Artificial intelligence arising from the combination of PatterNet and clustering analysis very precisely follows intuition of patterning/optical proximity correction experts paving the way toward human-like and human-friendly engineering tools.

EMODNet Bathymetry - building and providing a high resolution digital bathymetry for European seas

NASA Astrophysics Data System (ADS)

Schaap, D.

2016-12-01

Access to marine data is a key issue for the EU Marine Strategy Framework Directive and the EU Marine Knowledge 2020 agenda and includes the European Marine Observation and Data Network (EMODnet) initiative. The EMODnet Bathymetry project develops and publishes Digital Terrain Models (DTM) for the European seas. These are produced from survey and aggregated data sets that are indexed with metadata by adopting from SeaDataNet the Common Data Index (CDI) data discovery and access service and the Sextant data products catalogue service. SeaDataNet is a network of major oceanographic data centres around the European seas that manage, operate and further develop a pan-European infrastructure for marine and ocean data management. SeaDataNet is also setting and governing marine data standards, and exploring and establishing interoperability solutions to connect to other e-infrastructures on the basis of standards such as ISO and OGC. The SeaDataNet portal provides users a number of interrelated meta directories, an extensive range of controlled vocabularies, and the various SeaDataNet standards and tools. SeaDataNet at present gives overview and access to more than 1.8 million data sets for physical oceanography, chemistry, geology, geophysics, bathymetry and biology from more than 100 connected data centres from 34 countries riparian to European seas. The latest EMODnet Bathymetry DTM has a resolution of 1/8 arcminute * 1/8 arcminute and covers all European sea regions. Use is made of available and gathered surveys and already more than 13.000 surveys have been indexed by 27 European data providers from 15 countries. Also use is made of composite DTMs as generated and maintained by several data providers for their areas of interest. Already 44 composite DTMs are included in the Sextant data products catalogue. For areas without coverage use is made of the latest global DTM of GEBCO who is partner in the EMODnet Bathymetry project. In return GEBCO integrates the EMODnet DTM to achieve an enriched and better result. The catalogue services and the generated EMODnet can be queried and browsed at the dedicated EMODnet Bathymetry portal which also provides a versatile DTM viewing service with many relevant map layers and functions for retrieving. The EMODnet DTM is publicly available for downloading in various formats.

DOE Office of Scientific and Technical Information (OSTI.GOV)

The technology necessary to build net zero energy buildings (NZEBs) is ready and available today, however, building to net zero energy performance levels can be challenging. Energy efficiency measures, onsite energy generation resources, load matching and grid interaction, climatic factors, and local policies vary from location to location and require unique methods of constructing NZEBs. It is recommended that Components start looking into how to construct and operate NZEBs now as there is a learning curve to net zero construction and FY 2020 is just around the corner.

Implementation and Analysis of a Threat Model for IPv6 Host Autoconfiguration

DTIC Science & Technology

2006-09-01

Collision Generator”, two Denial of Service attacks. The software was developed in NetBeans IDE 5.0, and the comments were converted to Javadoc with the...appropriate NetBeans function. A. ICMPV6 SUPPORT FOR JPCAP As the attack uses ICMPv6 messages, a means must be provided to generate these messages...ICMP packet. * * Developed in NetBeans IDE 5.0 * Makes use of Jpcap 0.5.1 library * (http://netresearch.ics.uci.edu/kfujii/jpcap/doc

Unparalleled Need: Human Intelligence Collectors in the United States Army

DTIC Science & Technology

2013-03-01

a conventional threat that consists of large 5 signatures, such as discerning troop movement. However, it becomes invaluable when presented...1977 and 1997 comprise 27% of the current workforce and are referred to as “the Echo of the Baby Boom, Net Generation, Gen Y, or Millennials .”40 Most...January 2007 report from the Pew Research Center, 81% of 18 to 25 year olds polled said that getting rich is their generation’s most, or second

The long noncoding RNA landscape of neuroendocrine prostate cancer and its clinical implications.

PubMed

Ramnarine, Varune Rohan; Alshalalfa, Mohammed; Mo, Fan; Nabavi, Noushin; Erho, Nicholas; Takhar, Mandeep; Shukin, Robert; Brahmbhatt, Sonal; Gawronski, Alexander; Kobelev, Maxim; Nouri, Mannan; Lin, Dong; Tsai, Harrison; Lotan, Tamara L; Karnes, R Jefferey; Rubin, Mark A; Zoubeidi, Amina; Gleave, Martin E; Sahinalp, Cenk; Wyatt, Alexander W; Volik, Stanislav V; Beltran, Himisha; Davicioni, Elai; Wang, Yuzhuo; Collins, Colin C

2018-05-10

Treatment induced neuroendocrine prostate cancer (tNEPC) is an aggressive variant of late-stage metastatic castrate resistant (mCRPC) prostate cancer that commonly arises through neuroendocrine transdifferentiation (NEtD). Treatment options are limited, ineffective, and for most patients, results in death in less than a year. We previously developed a first-in-field patient-derived xenograft (PDX) model of NEtD. Longitudinal deep transcriptome profiling of this model enabled monitoring of dynamic transcriptional changes during NEtD and in the context of androgen deprivation. Long non-coding RNA (lncRNA) are implicated in cancer where they can control gene regulation. Until now the expression of lncRNAs during NEtD and their clinical associations were unexplored. We implemented a next-generation sequence analysis pipeline that can detect transcripts at low expression levels and built a genome-wide catalogue (n = 37,749) of lncRNAs. We applied this pipeline to 927 clinical samples and our high fidelity NEtD model LTL331 and identified 821 lncRNAs in NEPC. Among these are 122 lncRNAs that robustly distinguish NEPC from prostate adenocarcinoma (AD) patient tumours. The highest expressed lncRNAs within this signature are H19, LINC00617, and SSTR5-AS1. Another 742 are associated with the NEtD process and fall into four distinct patterns of expression (NEtD lncRNA Class I, II, III, and IV) in our PDX model and clinical samples. Each class has significant (z-scores>2) and unique enrichment for transcription factor binding site (TFBS) motifs in their sequences. Enriched TFBS include (1) TP53 and BRN1 in Class I, (2) ELF5, SPIC, and HOXD1 in Class II, (3) SPDEF in Class III, (4) HSF1 and FOXA1 in Class IV, and (5) TWIST1 when merging Class III with IV. Common TFBS in all NEtD lncRNA were also identified and include, E2F, REST, PAX5, PAX9, and STAF. Interrogation of the top deregulated candidates (n = 100) in radical prostatectomy adenocarcinoma samples with long-term follow-up (median 18 years) revealed significant clinicopathological associations. Specifically, we identified 25 that are associated with rapid metastasis following androgen deprivation therapy (ADT). Two of these lncRNAs (SSTR5-AS1 and LINC00514) stratified patients undergoing ADT based on patient outcome. To date, a comprehensive characterization of the dynamic landscape of lncRNAs during the NEtD process has not been performed. A temporal analysis of the PDX-based NEtD model has for the first time provided this dynamic landscape. TFBS analysis identified NEPC-related TF motifs present within the NEtD lncRNA sequences, suggesting functional roles for these lncRNAs in NEPC pathogenesis. Furthermore, select NEtD lncRNAs appear to be associated with metastasis and patients receiving ADT. Treatment-related metastasis is a clinical consequence of NEPC tumours. Top candidate lncRNAs FENDRR, H19, LINC00514, LINC00617, and SSTR5-AS1 identified in this study are implicated in the development of NEPC. We present here for the first time a genome-wide catalogue of NEtD lncRNAs that characterize the transdifferentiation process and a robust NEPC lncRNA patient expression signature. To accomplish this, we carried out the largest integrative study that applied a PDX NEtD model to clinical samples. These NEtD and NEPC lncRNAs are strong candidates for clinical biomarkers and therapeutic targets and warrant further investigation.

SeaDataNet II - EMODNet - building a pan-European infrastructure for marine and ocean data management

NASA Astrophysics Data System (ADS)

Schaap, Dick M. A.; Fichaut, Michele

2014-05-01

The second phase of the project SeaDataNet is well underway since October 2011 and is making good progress. The main objective is to improve operations and to progress towards an efficient data management infrastructure able to handle the diversity and large volume of data collected via research cruises and monitoring activities in European marine waters and global oceans. The SeaDataNet infrastructure comprises a network of interconnected data centres and a central SeaDataNet portal. The portal provides users a unified and transparent overview of the metadata and controlled access to the large collections of data sets, managed by the interconnected data centres, and the various SeaDataNet standards and tools,. Recently the 1st Innovation Cycle has been completed, including upgrading of the CDI Data Discovery and Access service to ISO 19139 and making it fully INSPIRE compliant. The extensive SeaDataNet Vocabularies have been upgraded too and implemented for all SeaDataNet European metadata directories. SeaDataNet is setting and governing marine data standards, and exploring and establishing interoperability solutions to connect to other e-infrastructures on the basis of standards of ISO (19115, 19139), OGC (WMS, WFS, CS-W and SWE), and OpenSearch. The population of directories has also increased considerably in cooperation and involvement in associated EU projects and initiatives. SeaDataNet now gives overview and access to more than 1.4 million data sets for physical oceanography, chemistry, geology, geophysics, bathymetry and biology from more than 90 connected data centres from 30 countries riparian to European seas. Access to marine data is also a key issue for the implementation of the EU Marine Strategy Framework Directive (MSFD). The EU communication 'Marine Knowledge 2020' underpins the importance of data availability and harmonising access to marine data from different sources. SeaDataNet qualified itself for leading the data management component of the EMODNet (European Marine Observation and Data Network) that is promoted in the EU Communication. In the past 4 years EMODNet portals have been initiated for marine data themes: digital bathymetry, chemistry, physical oceanography, geology, biology, and seabed habitat mapping. These portals are now being expanded to all European seas in successor projects, which started mid 2013 from EU DG MARE. EMODNet encourages more data providers to come forward for data sharing and participating in the process of making complete overviews and homogeneous data products. The EMODNet Bathymetry project is very illustrative for the synergy with SeaDataNet and added value of generating public data products. The project develops and publishes Digital Terrain Models (DTM) for the European seas. These are produced from survey and aggregated data sets. The portal provides a versatile DTM viewing service with many relevant map layers and functions for retrieving. A further refinement is taking place in the new phase. The presentation will give information on present services of the SeaDataNet infrastructure and services, highlight key achievements in SeaDataNet II so far, and give further insights in the EMODNet Bathymetry progress.

ROOT.NET: Using ROOT from .NET languages like C# and F#

NASA Astrophysics Data System (ADS)

Watts, G.

2012-12-01

ROOT.NET provides an interface between Microsoft's Common Language Runtime (CLR) and .NET technology and the ubiquitous particle physics analysis tool, ROOT. ROOT.NET automatically generates a series of efficient wrappers around the ROOT API. Unlike pyROOT, these wrappers are statically typed and so are highly efficient as compared to the Python wrappers. The connection to .NET means that one gains access to the full series of languages developed for the CLR including functional languages like F# (based on OCaml). Many features that make ROOT objects work well in the .NET world are added (properties, IEnumerable interface, LINQ compatibility, etc.). Dynamic languages based on the CLR can be used as well, of course (Python, for example). Additionally it is now possible to access ROOT objects that are unknown to the translation tool. This poster will describe the techniques used to effect this translation, along with performance comparisons, and examples. All described source code is posted on the open source site CodePlex.

Enabling Grid Computing resources within the KM3NeT computing model

NASA Astrophysics Data System (ADS)

Filippidis, Christos

2016-04-01

KM3NeT is a future European deep-sea research infrastructure hosting a new generation neutrino detectors that - located at the bottom of the Mediterranean Sea - will open a new window on the universe and answer fundamental questions both in particle physics and astrophysics. International collaborative scientific experiments, like KM3NeT, are generating datasets which are increasing exponentially in both complexity and volume, making their analysis, archival, and sharing one of the grand challenges of the 21st century. These experiments, in their majority, adopt computing models consisting of different Tiers with several computing centres and providing a specific set of services for the different steps of data processing such as detector calibration, simulation and data filtering, reconstruction and analysis. The computing requirements are extremely demanding and, usually, span from serial to multi-parallel or GPU-optimized jobs. The collaborative nature of these experiments demands very frequent WAN data transfers and data sharing among individuals and groups. In order to support the aforementioned demanding computing requirements we enabled Grid Computing resources, operated by EGI, within the KM3NeT computing model. In this study we describe our first advances in this field and the method for the KM3NeT users to utilize the EGI computing resources in a simulation-driven use-case.

Arizona | Midmarket Solar Policies in the United States | Solar Research |

Science.gov Websites

standard. Arizona has a net-metering program with no size limit but is specific to the customer's load % of customer's total connected load Aggregate cap: Not addressed Credit: Net excess generation is are exempt from Arizona Corporation Commission regulation. Community Solar There are currently no

Louisiana | Solar Research | NREL

Science.gov Websites

required to offer net metering for commercial and agricultural systems up to 300 kW. Commercial customers commercial and agricultural, 25 kW residential Aggregate cap: None Credit: Net excess generation is credited requirements are not addressed. System size limit: 300 kW for commercial and agricultural, 25 kW for

Utah | Midmarket Solar Policies in the United States | Solar Research |

Science.gov Websites

Credit: Net excess generation is credited at the retail rate for residential and small commercial customers; large commercial and industrial customers with demand charge may choose between valuing net cost) for residential taxpayers; $50,000 (or 10% of system cost) for commercial taxpayers. Renewable

Take the Science Fair Online!

ERIC Educational Resources Information Center

Tubbs, James

2007-01-01

The kids in today's classrooms spend lots of time playing video games, surfing the net, listening to iPods, and text messaging on cell phones. Known as Digital Kids and the Net Generation, they have grown up surrounded by digital media of all types (Tapscott 1999). Because they are already knowledgeable, why not use digital technologies to capture…

Net merit as a measure of lifetime profit: 2017 revision

USDA-ARS?s Scientific Manuscript database

Economic values in net merit (NM$) were updated in April 2017, cow livability (LIV) was included as a new trait, and body weight composite (BWC) replaced body size composite (BSC). Cows that die or are euthanized on the farm generate no beef income and may have more health expenses than cows that a...

Large-Scale Dynamic Observation Planning for Unmanned Surface Vessels

DTIC Science & Technology

2007-06-01

programming language. In addition, the useful development software NetBeans IDE is free and makes the use of Java very user-friendly. 92...3. We implemented the greedy and 3PAA algorithms in Java using the NetBeans IDE version 5.5. 4. The test datasets were generated in MATLAB. 5

Assessing alternative measures of wealth in health research.

PubMed

Cubbin, Catherine; Pollack, Craig; Flaherty, Brian; Hayward, Mark; Sania, Ayesha; Vallone, Donna; Braveman, Paula

2011-05-01

We assessed whether it would be feasible to replace the standard measure of net worth with simpler measures of wealth in population-based studies examining associations between wealth and health. We used data from the 2004 Survey of Consumer Finances (respondents aged 25-64 years) and the 2004 Health and Retirement Survey (respondents aged 50 years or older) to construct logistic regression models relating wealth to health status and smoking. For our wealth measure, we used the standard measure of net worth as well as 9 simpler measures of wealth, and we compared results among the 10 models. In both data sets and for both health indicators, models using simpler wealth measures generated conclusions about the association between wealth and health that were similar to the conclusions generated by models using net worth. The magnitude and significance of the odds ratios were similar for the covariates in multivariate models, and the model-fit statistics for models using these simpler measures were similar to those for models using net worth. Our findings suggest that simpler measures of wealth may be acceptable in population-based studies of health.

Financial methods for waterflooding injectate design

DOEpatents

Heneman, Helmuth J.; Brady, Patrick V.

2017-08-08

A method of selecting an injectate for recovering liquid hydrocarbons from a reservoir includes designing a plurality of injectates, calculating a net present value of each injectate, and selecting a candidate injectate based on the net present value. For example, the candidate injectate may be selected to maximize the net present value of a waterflooding operation.

Scoping study for compact high-field superconducting net energy tokamaks

NASA Astrophysics Data System (ADS)

Mumgaard, R. T.; Greenwald, M.; Freidberg, J. P.; Wolfe, S. M.; Hartwig, Z. S.; Brunner, D.; Sorbom, B. N.; Whyte, D. G.

2016-10-01

The continued development and commercialization of high temperature superconductors (HTS) may enable the construction of compact, net-energy tokamaks. HTS, in contrast to present generation low temperature superconductors, offers improved performance in high magnetic fields, higher current density, stronger materials, higher temperature operation, and simplified assembly. Using HTS along with community-consensus confinement physics (H98 =1) may make it possible to achieve net-energy (Q>1) or burning plasma conditions (Q>5) in DIII-D or ASDEX-U sized, conventional aspect ratio tokamaks. It is shown that, by operating at high plasma current and density enabled by the high magnetic field (B>10T), the required triple products may be achieved at plasma volumes under 20m3, major radii under 2m, with external heating powers under 40MW. This is at the scale of existing devices operated by laboratories, universities and companies. The trade-offs in the core heating, divertor heat exhaust, sustainment, stability, and proximity to known plasma physics limits are discussed in the context of the present tokamak experience base and the requirements for future devices. The resulting HTS-based design space is compared and contrasted to previous studies on high-field copper experiments with similar missions. The physics exploration conducted with such HTS devices could decrease the real and perceived risks of ITER exploitation, and aid in quickly developing commercially-applicable tokamak pilot plants and reactors.

MPL-Net Measurements of Aerosol and Cloud Vertical Distributions at Co-Located AERONET Sites

NASA Technical Reports Server (NTRS)

Welton, Ellsworth J.; Campbell, James R.; Berkoff, Timothy A.; Spinhirne, James D.; Tsay, Si-Chee; Holben, Brent; Starr, David OC. (Technical Monitor)

2002-01-01

In the early 1990s, the first small, eye-safe, and autonomous lidar system was developed, the Micropulse Lidar (MPL). The MPL acquires signal profiles of backscattered laser light from aerosols and clouds. The signals are analyzed to yield multiple layer heights, optical depths of each layer, average extinction-to-backscatter ratios for each layer, and profiles of extinction in each layer. In 2000, several MPL sites were organized into a coordinated network, called MPL-Net, by the Cloud and Aerosol Lidar Group at NASA Goddard Space Flight Center (GSFC) using funding provided by the NASA Earth Observing System. tn addition to the funding provided by NASA EOS, the NASA CERES Ground Validation Group supplied four MPL systems to the project, and the NASA TOMS group contributed their MPL for work at GSFC. The Atmospheric Radiation Measurement Program (ARM) also agreed to make their data available to the MPL-Net project for processing. In addition to the initial NASA and ARM operated sites, several other independent research groups have also expressed interest in joining the network using their own instruments. Finally, a limited amount of EOS funding was set aside to participate in various field experiments each year. The NASA Sensor Intercomparison and Merger for Biological and Interdisciplinary Oceanic Studies (SIMBIOS) project also provides funds to deploy their MPL during ocean research cruises. All together, the MPL-Net project has participated in four major field experiments since 2000. Most MPL-Net sites and field experiment locations are also co-located with sunphotometers in the NASA Aerosol Robotic Network. (AERONET). Therefore, at these locations data is collected on both aerosol and cloud vertical structure as well as column optical depth and sky radiance. Real-time data products are now available from most MPL-Net sites. Our real-time products are generated at times of AERONET aerosol optical depth (AOD) measurements. The AERONET AOD is used as input to our processing routines, which calculate the aerosol layer top height and extinction profile, and our MPL calibration value. A variety of other data products are available or under development. We present an overview of the MPL-Net project and discuss data products useful to the AERONET community. Results from several sites and field experiments will be presented.

Seismic Monitoring with NetQuakes: The First 75 in the Pacific Northwest

NASA Astrophysics Data System (ADS)

Bodin, P.; Vidale, J. E.; Luetgert, J. H.; Malone, S. D.; Delorey, A. A.; Steele, W. P.; Gibbons, D. A.; Walsh, L. K.

2011-12-01

NetQuakes accelerographs are relatively inexpensive Internet-aware appliances that we are using as part of our regional seismic monitoring program in the Pacific Northwest Seismic Network (PNSN). To date we have deployed approximately 65 units. By the end of 2011, we will have at least 75 systems sited and operating. The instruments are made by Swiss manufacturer GeoSig, Ltd., and have been obtained by PNSN through several cooperative programs with the US Geological Survey (USGS). The NetQuakes systems have increased the number of strong-motion stations in the Pacific Northwest by ~50%. NetQuakes instruments connect to the Internet via wired or wireless telemetry, obtain accurate timing vie Network Time Protocol, and are designed to be located in the ground floor of houses or small buildings. At PNSN we have concentrated on finding NetQuakes hosts by having technologically savvy homeowners self-identify as a response to news reports about the NetQuakes project. Potential hosts are prioritized by their proximity to target sites provided by a regional panel of experts who studied the region's strong-ground-motion monitoring needs. Recorded waveforms, triggered by strong motion or retrieved from a buffer of continuous data, are transmitted to Menlo Park, and then on to PNSN in Seattle. Data are available with latency of a few minutes to a little over an hour, and are automatically incorporated with the rest of PNSN network data for analysis and the generation of earthquake products. Triggered data may also be viewed by the public via the USGS website, [http://earthquake.usgs.gov/monitoring/netquakes/map/pacnw]. We present examples of ground motion recordings returned to date. Local earthquakes up to M4 (at a distance of ~60 km) reveal interesting patterns of local site effects. The 11 March M9 Tohoku, Japan earthquake produced ground motions recorded on the PNSN accelerographs, including many NetQuakes systems, that reveal the extent and severity of basin-related shaking amplification.

Evaluation of Advanced Stirling Convertor Net Heat Input Correlation Methods Using a Thermal Standard

NASA Technical Reports Server (NTRS)

Briggs, Maxwell H.; Schifer, Nicholas A.

2012-01-01

The U.S. Department of Energy (DOE) and Lockheed Martin Space Systems Company (LMSSC) have been developing the Advanced Stirling Radioisotope Generator (ASRG) for use as a power system for space science missions. This generator would use two high-efficiency Advanced Stirling Convertors (ASCs), developed by Sunpower Inc. and NASA Glenn Research Center (GRC). The ASCs convert thermal energy from a radioisotope heat source into electricity. As part of ground testing of these ASCs, different operating conditions are used to simulate expected mission conditions. These conditions require achieving a particular operating frequency, hot end and cold end temperatures, and specified electrical power output for a given net heat input. In an effort to improve net heat input predictions, numerous tasks have been performed which provided a more accurate value for net heat input into the ASCs, including testing validation hardware, known as the Thermal Standard, to provide a direct comparison to numerical and empirical models used to predict convertor net heat input. This validation hardware provided a comparison for scrutinizing and improving empirical correlations and numerical models of ASC-E2 net heat input. This hardware simulated the characteristics of an ASC-E2 convertor in both an operating and non-operating mode. This paper describes the Thermal Standard testing and the conclusions of the validation effort applied to the empirical correlation methods used by the Radioisotope Power System (RPS) team at NASA Glenn.

Methodology for the optimal design of an integrated first and second generation ethanol production plant combined with power cogeneration.

PubMed

Bechara, Rami; Gomez, Adrien; Saint-Antonin, Valérie; Schweitzer, Jean-Marc; Maréchal, François

2016-08-01

The application of methodologies for the optimal design of integrated processes has seen increased interest in literature. This article builds on previous works and applies a systematic methodology to an integrated first and second generation ethanol production plant with power cogeneration. The methodology breaks into process simulation, heat integration, thermo-economic evaluation, exergy efficiency vs. capital costs, multi-variable, evolutionary optimization, and process selection via profitability maximization. Optimization generated Pareto solutions with exergy efficiency ranging between 39.2% and 44.4% and capital costs from 210M$ to 390M$. The Net Present Value was positive for only two scenarios and for low efficiency, low hydrolysis points. The minimum cellulosic ethanol selling price was sought to obtain a maximum NPV of zero for high efficiency, high hydrolysis alternatives. The obtained optimal configuration presented maximum exergy efficiency, hydrolyzed bagasse fraction, capital costs and ethanol production rate, and minimum cooling water consumption and power production rate. Copyright © 2016 Elsevier Ltd. All rights reserved.

Mentoring the "Net Generation": Faculty Perspectives in Health Education

ERIC Educational Resources Information Center

Evans, Retta R.; Forbes, Laura

2012-01-01

A new generation of consumer and tech savvy college students have forever altered the method and degree of interaction between faculty and student. The purpose of the article is to describe the challenges of mentoring a new generation of health educators. The authors will summarize the literature on generational group characteristics that may…

Inclusive fitness and differential productivity across the life course determine intergenerational transfers in a small-scale human society.

PubMed

Hooper, Paul L; Gurven, Michael; Winking, Jeffrey; Kaplan, Hillard S

2015-03-22

Transfers of resources between generations are an essential element in current models of human life-history evolution accounting for prolonged development, extended lifespan and menopause. Integrating these models with Hamilton's theory of inclusive fitness, we predict that the interaction of biological kinship with the age-schedule of resource production should be a key driver of intergenerational transfers. In the empirical case of Tsimane' forager-horticulturalists in Bolivian Amazonia, we provide a detailed characterization of net transfers of food according to age, sex, kinship and the net need of donors and recipients. We show that parents, grandparents and siblings provide significant net downward transfers of food across generations. We demonstrate that the extent of provisioning responds facultatively to variation in the productivity and demographic composition of families, as predicted by the theory. We hypothesize that the motivation to provide these critical transfers is a fundamental force that binds together human nuclear and extended families. The ubiquity of three-generational families in human societies may thus be a direct reflection of fundamental evolutionary constraints on an organism's life-history and social organization.

Is there a “net generation” in veterinary medicine? A comparative study on the use of the Internet and Web 2.0 by students and the veterinary profession

PubMed Central

Tenhaven, Christoph; Tipold, Andrea; Fischer, Martin R.; Ehlers, Jan P.

2013-01-01

Introduction: Informal and formal lifelong learning is essential at university and in the workplace. Apart from classical learning techniques, Web 2.0 tools can be used. It is controversial whether there is a so-called net generation amongst people under 30. Aims: To test the hypothesis that a net generation among students and young veterinarians exists. Methods: An online survey of students and veterinarians was conducted in the German-speaking countries which was advertised via online media and traditional print media. Results: 1780 people took part in the survey. Students and veterinarians have different usage patterns regarding social networks (91.9% vs. 69%) and IM (55.9% vs. 24.5%). All tools were predominantly used passively and in private, to a lesser extent also professionally and for studying. Outlook: The use of Web 2.0 tools is useful, however, teaching information and media skills, preparing codes of conduct for the internet and verification of user generated content is essential. PMID:23467682

Global Patterns in Human Consumption of Net Primary Production

NASA Technical Reports Server (NTRS)

Imhoff, Marc L.; Bounoua, Lahouari; Ricketts, Taylor; Loucks, Colby; Harriss, Robert; Lawrence William T.

2004-01-01

The human population and its consumption profoundly affect the Earth's ecosystems. A particularly compelling measure of humanity's cumulative impact is the fraction of the planet's net primary production that we appropriate for our Net primary production-the net amount of solar energy converted to plant organic matter through photosynthesis-can be measured in units of elemental carbon and represents the primary food energy source for the world's ecosystems. Human appropriation of net primary production, apart from leaving less for other species to use, alters the composition of the atmosphere, levels of biodiversity, flows within food webs and the provision of important primary production required by humans and compare it to the total amount generated on the landscape. We then derive a spatial ba!mce sheet of net primary production supply and demand for the world. We show that human appropriation of net primary production varies spatially from almost zero to many times the local primary production. These analyses reveal the uneven footprint of human consumption and related environmental impacts, indicate the degree to which human populations depend on net primary production "imports" and suggest policy options for slowing future growth of human appropriation of net primary production.

Maximum Work of Free-Piston Stirling Engine Generators

NASA Astrophysics Data System (ADS)

Kojima, Shinji

2017-04-01

Using the method of adjoint equations described in Ref. [1], we have calculated the maximum thermal efficiencies that are theoretically attainable by free-piston Stirling and Carnot engine generators by considering the work loss due to friction and Joule heat. The net work done by the Carnot cycle is negative even when the duration of heat addition is optimized to give the maximum amount of heat addition, which is the same situation for the Brayton cycle described in our previous paper. For the Stirling cycle, the net work done is positive, and the thermal efficiency is greater than that of the Otto cycle described in our previous paper by a factor of about 2.7-1.4 for compression ratios of 5-30. The Stirling cycle is much better than the Otto, Brayton, and Carnot cycles. We have found that the optimized piston trajectories of the isothermal, isobaric, and adiabatic processes are the same when the compression ratio and the maximum volume of the same working fluid of the three processes are the same, which has facilitated the present analysis because the optimized piston trajectories of the Carnot and Stirling cycles are the same as those of the Brayton and Otto cycles, respectively.

Evaluating renewable natural resources flow and net primary productivity with a GIS-Emergy approach: A case study of Hokkaido, Japan.

PubMed

Wang, Chengdong; Zhang, Shenyan; Yan, Wanglin; Wang, Renqing; Liu, Jian; Wang, Yutao

2016-11-18

Renewable natural resources, such as solar radiation, rainfall, wind, and geothermal heat, together with ecosystem services, provide the elementary supports for the sustainable development of human society. To improve regional sustainability, we studied the spatial distributions and quantities of renewable natural resources and net primary productivity (NPP) in Hokkaido, which is the second largest island of Japan. With the help of Geographic Information System (GIS) software, distribution maps for each type of renewable natural resource were generated by kriging interpolation based on statistical records. A composite map of the flow of all types of renewable natural resources was also generated by map layer overlapping. Additionally, we utilized emergy analysis to convert each renewable flow with different attributes into a unified unit (i.e., solar equivalent joules [sej]). As a result, the spatial distributions of the flow of renewable natural resources of the Hokkaido region are presented in the form of thematic emergy maps. Thus, the areas with higher renewable emergy can be easily visualized and identified. The dominant renewable flow in certain areas can also be directly distinguished. The results can provide useful information for regional sustainable development, environmental conservation and ecological management.

Evaluating renewable natural resources flow and net primary productivity with a GIS-Emergy approach: A case study of Hokkaido, Japan

PubMed Central

Wang, Chengdong; Zhang, Shenyan; Yan, Wanglin; Wang, Renqing; Liu, Jian; Wang, Yutao

2016-01-01

Renewable natural resources, such as solar radiation, rainfall, wind, and geothermal heat, together with ecosystem services, provide the elementary supports for the sustainable development of human society. To improve regional sustainability, we studied the spatial distributions and quantities of renewable natural resources and net primary productivity (NPP) in Hokkaido, which is the second largest island of Japan. With the help of Geographic Information System (GIS) software, distribution maps for each type of renewable natural resource were generated by kriging interpolation based on statistical records. A composite map of the flow of all types of renewable natural resources was also generated by map layer overlapping. Additionally, we utilized emergy analysis to convert each renewable flow with different attributes into a unified unit (i.e., solar equivalent joules [sej]). As a result, the spatial distributions of the flow of renewable natural resources of the Hokkaido region are presented in the form of thematic emergy maps. Thus, the areas with higher renewable emergy can be easily visualized and identified. The dominant renewable flow in certain areas can also be directly distinguished. The results can provide useful information for regional sustainable development, environmental conservation and ecological management. PMID:27857230

Variability in large-scale wind power generation: Variability in large-scale wind power generation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kiviluoma, Juha; Holttinen, Hannele; Weir, David

2015-10-25

The paper demonstrates the characteristics of wind power variability and net load variability in multiple power systems based on real data from multiple years. Demonstrated characteristics include probability distribution for different ramp durations, seasonal and diurnal variability and low net load events. The comparison shows regions with low variability (Sweden, Spain and Germany), medium variability (Portugal, Ireland, Finland and Denmark) and regions with higher variability (Quebec, Bonneville Power Administration and Electric Reliability Council of Texas in North America; Gansu, Jilin and Liaoning in China; and Norway and offshore wind power in Denmark). For regions with low variability, the maximum 1more » h wind ramps are below 10% of nominal capacity, and for regions with high variability, they may be close to 30%. Wind power variability is mainly explained by the extent of geographical spread, but also higher capacity factor causes higher variability. It was also shown how wind power ramps are autocorrelated and dependent on the operating output level. When wind power was concentrated in smaller area, there were outliers with high changes in wind output, which were not present in large areas with well-dispersed wind power.« less

Accurate pan-specific prediction of peptide-MHC class II binding affinity with improved binding core identification.

PubMed

Andreatta, Massimo; Karosiene, Edita; Rasmussen, Michael; Stryhn, Anette; Buus, Søren; Nielsen, Morten

2015-11-01

A key event in the generation of a cellular response against malicious organisms through the endocytic pathway is binding of peptidic antigens by major histocompatibility complex class II (MHC class II) molecules. The bound peptide is then presented on the cell surface where it can be recognized by T helper lymphocytes. NetMHCIIpan is a state-of-the-art method for the quantitative prediction of peptide binding to any human or mouse MHC class II molecule of known sequence. In this paper, we describe an updated version of the method with improved peptide binding register identification. Binding register prediction is concerned with determining the minimal core region of nine residues directly in contact with the MHC binding cleft, a crucial piece of information both for the identification and design of CD4(+) T cell antigens. When applied to a set of 51 crystal structures of peptide-MHC complexes with known binding registers, the new method NetMHCIIpan-3.1 significantly outperformed the earlier 3.0 version. We illustrate the impact of accurate binding core identification for the interpretation of T cell cross-reactivity using tetramer double staining with a CMV epitope and its variants mapped to the epitope binding core. NetMHCIIpan is publicly available at http://www.cbs.dtu.dk/services/NetMHCIIpan-3.1 .

Real-time optical correlator using computer-generated holographic filter on a liquid crystal light valve

NASA Technical Reports Server (NTRS)

Chao, Tien-Hsin; Yu, Jeffrey

1990-01-01

Limitations associated with the binary phase-only filter often used in optical correlators are presently circumvented in the writing of complex-valued data on a gray-scale spatial light modulator through the use of a computer-generated hologram (CGH) algorithm. The CGH encodes complex-valued data into nonnegative real CGH data in such a way that it may be encoded in any of the available gray-scale spatial light modulators. A CdS liquid-crystal light valve is used for the complex-valued CGH encoding; computer simulations and experimental results are compared, and the use of such a CGH filter as the synapse hologram in a holographic optical neural net is discussed.

Asynchronous oscillations of rigid rods drive viscous fluid to swirl

NASA Astrophysics Data System (ADS)

Hayashi, Rintaro; Takagi, Daisuke

2017-12-01

We present a minimal system for generating flow at low Reynolds number by oscillating a pair of rigid rods in silicone oil. Experiments show that oscillating them in phase produces no net flow, but a phase difference alone can generate rich flow fields. Tracer particles follow complex trajectory patterns consisting of small orbital movements every cycle and then drifting or swirling in larger regions after many cycles. Observations are consistent with simulations performed using the method of regularized Stokeslets, which reveal complex three-dimensional flow structures emerging from simple oscillatory actuation. Our findings reveal the basic underlying flow structure around oscillatory protrusions such as hairs and legs as commonly featured on living and nonliving bodies.

Nicotine Levels and Presence of Selected Tobacco-Derived Toxins in Tobacco Flavoured Electronic Cigarette Refill Liquids

PubMed Central

Farsalinos, Konstantinos E.; Gillman, I. Gene; Melvin, Matt S.; Paolantonio, Amelia R.; Gardow, Wendy J.; Humphries, Kathy E.; Brown, Sherri E.; Poulas, Konstantinos; Voudris, Vassilis

2015-01-01

Background. Some electronic cigarette (EC) liquids of tobacco flavour contain extracts of cured tobacco leaves produced by a process of solvent extraction and steeping. These are commonly called Natural Extract of Tobacco (NET) liquids. The purpose of the study was to evaluate nicotine levels and the presence of tobacco-derived toxins in tobacco-flavoured conventional and NET liquids. Methods. Twenty-one samples (10 conventional and 11 NET liquids) were obtained from the US and Greek market. Nicotine levels were measured and compared with labelled values. The levels of tobacco-derived chemicals were compared with literature data on tobacco products. Results. Twelve samples had nicotine levels within 10% of the labelled value. Inconsistency ranged from −21% to 22.1%, with no difference observed between conventional and NET liquids. Tobacco-specific nitrosamines (TSNAs) were present in all samples at ng/mL levels. Nitrates were present almost exclusively in NET liquids. Acetaldehyde was present predominantly in conventional liquids while formaldehyde was detected in almost all EC liquids at trace levels. Phenols were present in trace amounts, mostly in NET liquids. Total TSNAs and nitrate, which are derived from the tobacco plant, were present at levels 200–300 times lower in 1 mL of NET liquids compared to 1 gram of tobacco products. Conclusions. NET liquids contained higher levels of phenols and nitrates, but lower levels of acetaldehyde compared to conventional EC liquids. The lower levels of tobacco-derived toxins found in NET liquids compared to tobacco products indicate that the extraction process used to make these products did not transfer a significant amount of toxins to the NET. Overall, all EC liquids contained far lower (by 2–3 orders of magnitude) levels of the tobacco-derived toxins compared to tobacco products. PMID:25811768

Nicotine levels and presence of selected tobacco-derived toxins in tobacco flavoured electronic cigarette refill liquids.

PubMed

Farsalinos, Konstantinos E; Gillman, I Gene; Melvin, Matt S; Paolantonio, Amelia R; Gardow, Wendy J; Humphries, Kathy E; Brown, Sherri E; Poulas, Konstantinos; Voudris, Vassilis

2015-03-24

Some electronic cigarette (EC) liquids of tobacco flavour contain extracts of cured tobacco leaves produced by a process of solvent extraction and steeping. These are commonly called Natural Extract of Tobacco (NET) liquids. The purpose of the study was to evaluate nicotine levels and the presence of tobacco-derived toxins in tobacco-flavoured conventional and NET liquids. Twenty-one samples (10 conventional and 11 NET liquids) were obtained from the US and Greek market. Nicotine levels were measured and compared with labelled values. The levels of tobacco-derived chemicals were compared with literature data on tobacco products. Twelve samples had nicotine levels within 10% of the labelled value. Inconsistency ranged from -21% to 22.1%, with no difference observed between conventional and NET liquids. Tobacco-specific nitrosamines (TSNAs) were present in all samples at ng/mL levels. Nitrates were present almost exclusively in NET liquids. Acetaldehyde was present predominantly in conventional liquids while formaldehyde was detected in almost all EC liquids at trace levels. Phenols were present in trace amounts, mostly in NET liquids. Total TSNAs and nitrate, which are derived from the tobacco plant, were present at levels 200-300 times lower in 1 mL of NET liquids compared to 1 gram of tobacco products. NET liquids contained higher levels of phenols and nitrates, but lower levels of acetaldehyde compared to conventional EC liquids. The lower levels of tobacco-derived toxins found in NET liquids compared to tobacco products indicate that the extraction process used to make these products did not transfer a significant amount of toxins to the NET. Overall, all EC liquids contained far lower (by 2-3 orders of magnitude) levels of the tobacco-derived toxins compared to tobacco products.

Climatic Forecasting of Net Infiltration at Yucca Mountain, Using Analogue Meteorological Data

NASA Astrophysics Data System (ADS)

Faybishenko, B.

2005-12-01

Net infiltration is a key hydrologic parameter that, throughout the unsaturated zone, controls the rate of deep percolation, the groundwater recharge, radionuclide transport, and seepage into underground tunnels. Because net infiltration is largely affected by climatic conditions, future changes in climatic conditions will potentially alter net infiltration. The objectives of this presentation are to: (1) Present a conceptual model and a semi-empirical approach for regional climatic forecasting of net infiltration, based on precipitation and temperature data from analogue meteorological stations; and (2) Demonstrate the results of forecasting net infiltration for future climates - interglacial, monsoon and glacial - over the Yucca Mountain region for a period of 500,000 years. Calculations of net infiltration were performed using a modified Budyko's water-balance model, and potential evapotranspiration was evaluated from the temperature-based Thornthwaite formula. (Both Budyko's and Thornthwaite's formulae have been used broadly in hydrological studies.) The results of these calculations were used for ranking net infiltration, along with aridity and precipitation-effectiveness (P-E) indices, for future climatic scenarios. Using this approach, we determined a general trend of increasing net infiltration from the present-day (interglacial) climate to the monsoon, intermediate (glacial transition) climate, a trend that continued into the glacial climate time frame. The ranking of aridity and P-E indices is practically the same as that for net infiltration. Validation of the computed net infiltration rates yielded a good match with other field and modeling study results related to groundwater recharge and net infiltration evaluation.

Soldier communication net for the 21st century digitized battlespace

NASA Astrophysics Data System (ADS)

Mu, Libo; Zhang, Yutian

1999-07-01

This paper present soldier communication net scheme, which survives and operates in the 21st century battlefield environment. First, it analyzes the features, the need, function of the soldier communication net on the 21st century battlefield environment. Secondly it presents a layered model of the soldier communication net, derived from the OSI theory, and discusses the design of the 3 layers, link layer, link controller and input/output applications layer. Thirdly, it present some key technical discussion concerning with the direct-sequence-spread-spectrum communication, code/decode and low power consumption. Finally, it gives the conclusion that spread spectrum time division system is the best scheme of soldier communication net.

Dark matter and the baryon asymmetry of the universe.

PubMed

Farrar, Glennys R; Zaharijas, Gabrijela

2006-02-03

We present a mechanism to generate the baryon asymmetry of the Universe which preserves the net baryon number created in the big bang. If dark matter particles carry baryon number Bx, and sigmaxannih

Magnetohydrodynamics (MHD) Engineering Test Facility (ETF) 200 MWe power plant. Design Requirements Document (DRD)

NASA Technical Reports Server (NTRS)

Rigo, H. S.; Bercaw, R. W.; Burkhart, J. A.; Mroz, T. S.; Bents, D. J.; Hatch, A. M.

1981-01-01

A description and the design requirements for the 200 MWe (nominal) net output MHD Engineering Test Facility (ETF) Conceptual Design, are presented. Performance requirements for the plant are identified and process conditions are indicated at interface stations between the major systems comprising the plant. Also included are the description, functions, interfaces and requirements for each of these major systems. The lastest information (1980-1981) from the MHD technology program are integrated with elements of a conventional steam electric power generating plant.

Net Generation's Learning Styles in Nursing Education.

PubMed

Christodoulou, Eleni; Kalokairinou, Athina

2015-01-01

Numerous surveys have confirmed that emerging technologies and Web 2.0 tools have been a defining feature in the lives of current students, estimating that there is a fundamental shift in the way young people communicate, socialize and learn. Nursing students in higher education are characterized as digital literate with distinct traits which influence their learning styles. Millennials exhibit distinct learning preferences such as teamwork, experiential activities, structure, instant feedback and technology integration. Higher education institutions should be aware of the implications of the Net Generation coming to university and be prepared to meet their expectations and learning needs.

Evaluation of runaway-electron effects on plasma-facing components for NET

NASA Astrophysics Data System (ADS)

Bolt, H.; Calén, H.

1991-03-01

Runaway electrons which are generated during disruptions can cause serious damage to plasma facing components in a next generation device like NET. A study was performed to quantify the response of NET plasma facing components to runaway-electron impact. For the determination of the energy deposition in the component materials Monte Carlo computations were performed. Since the subsurface metal structures can be strongly heated under runaway-electron impact from the computed results damage threshold values for the thermal excursions were derived. These damage thresholds are strongly dependent on the materials selection and the component design. For a carbonmolybdenum divertor with 10 and 20 mm carbon armour thickness and 1 degree electron incidence the damage thresholds are 100 MJ/m 2 and 220 MJ/m 2. The thresholds for a carbon-copper divertor under the same conditions are about 50% lower. On the first wall damage is anticipated for energy depositions above 180 MJ/m 2.

A technique for global monitoring of net solar irradiance at the ocean surface. II - Validation

NASA Technical Reports Server (NTRS)

Chertock, Beth; Frouin, Robert; Gautier, Catherine

1992-01-01

The generation and validation of the first satellite-based long-term record of surface solar irradiance over the global oceans are addressed. The record is generated using Nimbus-7 earth radiation budget (ERB) wide-field-of-view plentary-albedo data as input to a numerical algorithm designed and implemented based on radiative transfer theory. The mean monthly values of net surface solar irradiance are computed on a 9-deg latitude-longitude spatial grid for November 1978-October 1985. The new data set is validated in comparisons with short-term, regional, high-resolution, satellite-based records. The ERB-based values of net surface solar irradiance are compared with corresponding values based on radiance measurements taken by the Visible-Infrared Spin Scan Radiometer aboard GOES series satellites. Errors in the new data set are estimated to lie between 10 and 20 W/sq m on monthly time scales.

Web 2 Technologies for Net Native Language Learners: A "Social CALL"

ERIC Educational Resources Information Center

Karpati, Andrea

2009-01-01

In order to make optimal educational use of social spaces offered by thousands of international communities in the second generation web applications termed Web 2 or Social Web, ICT competences as well as social skills are needed for both teachers and learners. The paper outlines differences in competence structures of Net Natives (who came of age…

Standards for the 21st-Century Learner: Comparisons with NETS and State Standards

ERIC Educational Resources Information Center

Pappas, Marjorie

2008-01-01

The American Association of School Librarians (AASL) and the International Society for Technology in Education (ISTE) have both recently launched new standards. These are known as the "AASL Standards for the 21st-Century Learner" and "The National Educational Technology Standards for Students: The Next Generation" (NETS). The standards from each…

Network Exploration and Vulnerability Assessment Using a Combined Blackbox and Whitebox Analysis Approach

DTIC Science & Technology

2010-03-01

Employ NetFlow on Edge Router ......................................... 45 E. IMPLEMENT AN INTEGRATED VULNERABILITY ASSESSMENT. 48 1. Conduct...45 Figure 18. Netflow Information on Unauthorized Connections ............................ 46 Figure 19. Algorithm for Detecting...indicating that an attack has being initiated from this port. Figure 17. Information on Traffic Generated by Suspicious Host 3. Employ NetFlow

The effects of tropospheric ozone on net primary productivity and implications for climate change.

PubMed

Ainsworth, Elizabeth A; Yendrek, Craig R; Sitch, Stephen; Collins, William J; Emberson, Lisa D

2012-01-01

Tropospheric ozone (O(3)) is a global air pollutant that causes billions of dollars in lost plant productivity annually. It is an important anthropogenic greenhouse gas, and as a secondary air pollutant, it is present at high concentrations in rural areas far from industrial sources. It also reduces plant productivity by entering leaves through the stomata, generating other reactive oxygen species and causing oxidative stress, which in turn decreases photosynthesis, plant growth, and biomass accumulation. The deposition of O(3) into vegetation through stomata is an important sink for tropospheric O(3), but this sink is modified by other aspects of environmental change, including rising atmospheric carbon dioxide concentrations, rising temperature, altered precipitation, and nitrogen availability. We review the atmospheric chemistry governing tropospheric O(3) mass balance, the effects of O(3) on stomatal conductance and net primary productivity, and implications for agriculture, carbon sequestration, and climate change.

Polynomial algebra of discrete models in systems biology.

PubMed

Veliz-Cuba, Alan; Jarrah, Abdul Salam; Laubenbacher, Reinhard

2010-07-01

An increasing number of discrete mathematical models are being published in Systems Biology, ranging from Boolean network models to logical models and Petri nets. They are used to model a variety of biochemical networks, such as metabolic networks, gene regulatory networks and signal transduction networks. There is increasing evidence that such models can capture key dynamic features of biological networks and can be used successfully for hypothesis generation. This article provides a unified framework that can aid the mathematical analysis of Boolean network models, logical models and Petri nets. They can be represented as polynomial dynamical systems, which allows the use of a variety of mathematical tools from computer algebra for their analysis. Algorithms are presented for the translation into polynomial dynamical systems. Examples are given of how polynomial algebra can be used for the model analysis. alanavc@vt.edu Supplementary data are available at Bioinformatics online.

A Bio-Economic Case Study of Canadian Honey Bee (Hymenoptera: Apidae) Colonies: Marker-Assisted Selection (MAS) in Queen Breeding Affects Beekeeper Profits

PubMed Central

Baylis, Kathy; Hoover, Shelley E.; Currie, Rob W.; Melathopoulos, Andony P.; Pernal, Stephen F.; Foster, Leonard J.; Guarna, M. Marta

2017-01-01

Abstract Over the past decade in North America and Europe, winter losses of honey bee (Hymenoptera: Apidae) colonies have increased dramatically. Scientific consensus attributes these losses to multifactorial causes including altered parasite and pathogen profiles, lack of proper nutrition due to agricultural monocultures, exposure to pesticides, management, and weather. One method to reduce colony loss and increase productivity is through selective breeding of queens to produce disease-, pathogen-, and mite-resistant stock. Historically, the only method for identifying desirable traits in honey bees to improve breeding was through observation of bee behavior. A team of Canadian scientists have recently identified markers in bee antennae that correspond to behavioral traits in bees and can be tested for in a laboratory. These scientists have demonstrated that this marker-assisted selection (MAS) can be used to produce hygienic, pathogen-resistant honey bee colonies. Based on this research, we present a beekeeping case study where a beekeeper’s profit function is used to evaluate the economic impact of adopting colonies selected for hygienic behavior using MAS into an apiary. Our results show a net profit gain from an MAS colony of between 2% and 5% when Varroa mites are effectively treated. In the case of ineffective treatment, MAS generates a net profit benefit of between 9% and 96% depending on the Varroa load. When a Varroa mite population has developed some treatment resistance, we show that MAS colonies generate a net profit gain of between 8% and 112% depending on the Varroa load and degree of treatment resistance. PMID:28334400

Incorporating indirect costs into a cost-benefit analysis of laparoscopic adjustable gastric banding.

PubMed

Finkelstein, Eric A; Allaire, Benjamin T; Dibonaventura, Marco Dacosta; Burgess, Somali M

2012-01-01

The objective of this study was to estimate the time to breakeven and 5-year net costs of laparoscopic adjustable gastric banding (LAGB) taking both direct and indirect costs and cost savings into account. Estimates of direct cost savings from LAGB were available from the literature. Although longitudinal data on indirect cost savings were not available, these estimates were generated by quantifying the relationship between medical expenditures and absenteeism and between medical expenditures and presenteeism (reduced on-the-job productivity) and combining these elasticity estimates with estimates of the direct cost savings to generate total savings. These savings were then combined with the direct and indirect costs of the procedure to quantify net savings. By including indirect costs, the time to breakeven was reduced by half a year, from 16 to 14 quarters. After 5 years, net savings in medical expenditures from a gastric banding procedure were estimated to be $4970 (±$3090). Including absenteeism increased savings to $6180 (±$3550). Savings were further increased to $10,960 (±$5864) when both absenteeism and presenteeism estimates were included. This study presented a novel approach for including absenteeism and presenteeism estimates in cost-benefit analyses. Application of the approach to gastric banding among surgery-eligible obese employees revealed that the inclusion of indirect costs and cost savings improves the business case for the procedure. This approach can easily be extended to other populations and treatments. Copyright © 2012 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.

Infrared video tracking of Anopheles gambiae at insecticide-treated bed nets reveals rapid decisive impact after brief localised net contact

PubMed Central

Parker, Josephine E.A.; Angarita-Jaimes, Natalia; Abe, Mayumi; Towers, Catherine E.; Towers, David; McCall, Philip J.

2015-01-01

Long-lasting insecticidal bed nets (LLINs) protect humans from malaria transmission and are fundamental to malaria control worldwide, but little is known of how mosquitoes interact with nets. Elucidating LLIN mode of action is essential to maintain or improve efficacy, an urgent need as emerging insecticide resistance threatens their future. Tracking multiple free-flying Anopheles gambiae responding to human-occupied bed nets in a novel large-scale system, we characterised key behaviours and events. Four behavioural modes with different levels of net contact were defined: swooping, visiting, bouncing and resting. Approximately 75% of all activity occurred at the bed net roof where multiple brief contacts were focussed above the occupant’s torso. Total flight and net contact times were lower at LLINs than untreated nets but the essential character of the response was unaltered. LLINs did not repel mosquitoes but impacted rapidly: LLIN contact of less than 1 minute per mosquito during the first ten minutes reduced subsequent activity; after thirty minutes, activity at LLINs was negligible. Velocity measurements showed that mosquitoes detected nets, including unbaited untreated nets, prior to contact. This is the most complete characterisation of mosquito-LLIN interactions to date, and reveals many aspects of LLIN mode of action, important for developing the next generation of LLINs. PMID:26323965

Electric Vehicle Charging and the California Power Sector: Evaluating the Effect of Location and Time on Greenhouse Gas Emissions

NASA Astrophysics Data System (ADS)

Sohnen, Julia Meagher

This thesis explores the implications of the increased adoption of plug-in electric vehicles in California through its effect on the operation of the state's electric grid. The well-to-wheels emissions associated with driving an electric vehicle depend on the resource mix of the electricity grid used to charge the battery. We present a new least-cost dispatch model, EDGE-NET, for the California electricity grid consisting of interconnected sub-regions that encompass the six largest state utilities that can be used to evaluate the impact of growing electric vehicle demand on existing power grid infrastructure system and energy resources. This model considers spatiality and temporal dynamics of energy demand and supply when determining the regional impacts of additional charging profiles on the current electricity network. Model simulation runs for one year show generation and transmission congestion to be reasonable similar to historical data. Model simulation results show that average emissions and system costs associated with electricity generation vary significantly by time of day, season, and location. Marginal cost and emissions also exhibit seasonal and diurnal differences, but show less spatial variation. Sensitivity of demand analysis shows that the relative changes to average emissions and system costs respond asymmetrically to increases and decreases in electricity demand. These results depend on grid mix at the time and the marginal power plant type. In minimizing total system cost, the model will choose to dispatch the lowest-cost resource to meet additional vehicle demand, regardless of location, as long as transmission capacity is available. Location of electric vehicle charging has a small effect on the marginal greenhouse gas emissions associated with additional generation, due to electricity losses in the transmission grid. We use a geographically explicit, charging assessment model for California to develop and compare the effects of two charging profiles. Comparison of these two basic scenarios points to savings in greenhouse gas emissions savings and operational costs from delayed charging of electric vehicles. Vehicle charging simulations confirm that plug-in electric vehicles alone are unlikely to require additional generation or transmission infrastructure. EDGE-NET was successfully benchmarked against historical data for the present grid but additional work is required to expand the model for future scenario evaluation. We discuss how the model might be adapted for high penetrations of variable renewable energy resources, and the use of grid storage. Renewable resources such as wind and solar vary in California vary significantly by time-of-day, season, and location. However, combination of multiple resources from different geographic regions through transmission grid interconnection is expected to help mitigate the impacts of variability. EDGE-NET can evaluate interaction of supply and demand through the existing transmission infrastructure and can identify any critical network bottlenecks or areas for expansion. For this reason, EDGE-NET will be an important tool to evaluate energy policy scenarios.

Feasibility of biogas and energy generation from poultry manure in Brazil.

PubMed

Ribeiro, Eruin M; Mambeli Barros, Regina; Tiago Filho, Geraldo Lúcio; Dos Santos, Ivan Felipe S; Sampaio, Luma C; Dos Santos, Ticiane V; da Silva, Fernando dGB; Silva, Ana Paula M; de Freitas, João Victor R

2018-03-01

The aim of the present study is to experimentally measure the volume and composition of biogas produced from the anaerobic biodigestion of laying-hen manure from poultry farms in Itanhandu-MG, Brazil, so that the biogas can be used to generate energy. Two experiments (E1 and E2) were used to characterise the biogas quantities and compositions at room temperature and at a controlled temperature of 36 °C, respectively. The biogas production and calculated net power from the exploitation of biogas energy were compared with the results obtained from methods proposed by the Environmental Company of the State of São Paulo (CETESB, an acronym in Portuguese) using the 'Biogas: Generation and energy use - effluent and rural waste' software 1.0, Brasília-DF, Brazil. In addition, after a time equal to the hydraulic retention time subsequent to biodigester loading, the parameters were analysed and correlated with the organic matter content in the substrates. The effluents were subsequently compared with verify the degree of degradability. The biogas volumes were estimated to be 0.143 m 3  kg VTS -1 for E1 and 0.283 m 3  kg VTS -1 for E2. If the poultry farm considered in this case study uses manure to generate energy, then the estimated energy generation based on the data from experiments E1 and E2 will result in net energy values of 683 MW h y -1 and 27,160 MW h y -1 , given 620 MW h y -1 for sludge heating in E2. The energy production values from the simulations of the E1 and E2 experiments did not demonstrate economic viability under the studied conditions.

AllergenFP: allergenicity prediction by descriptor fingerprints.

PubMed

Dimitrov, Ivan; Naneva, Lyudmila; Doytchinova, Irini; Bangov, Ivan

2014-03-15

Allergenicity, like antigenicity and immunogenicity, is a property encoded linearly and non-linearly, and therefore the alignment-based approaches are not able to identify this property unambiguously. A novel alignment-free descriptor-based fingerprint approach is presented here and applied to identify allergens and non-allergens. The approach was implemented into a four step algorithm. Initially, the protein sequences are described by amino acid principal properties as hydrophobicity, size, relative abundance, helix and β-strand forming propensities. Then, the generated strings of different length are converted into vectors with equal length by auto- and cross-covariance (ACC). The vectors were transformed into binary fingerprints and compared in terms of Tanimoto coefficient. The approach was applied to a set of 2427 known allergens and 2427 non-allergens and identified correctly 88% of them with Matthews correlation coefficient of 0.759. The descriptor fingerprint approach presented here is universal. It could be applied for any classification problem in computational biology. The set of E-descriptors is able to capture the main structural and physicochemical properties of amino acids building the proteins. The ACC transformation overcomes the main problem in the alignment-based comparative studies arising from the different length of the aligned protein sequences. The conversion of protein ACC values into binary descriptor fingerprints allows similarity search and classification. The algorithm described in the present study was implemented in a specially designed Web site, named AllergenFP (FP stands for FingerPrint). AllergenFP is written in Python, with GIU in HTML. It is freely accessible at http://ddg-pharmfac.net/Allergen FP. idoytchinova@pharmfac.net or ivanbangov@shu-bg.net.

Optics-Only Calibration of a Neural-Net Based Optical NDE Method for Structural Health Monitoring

NASA Technical Reports Server (NTRS)

Decker, Arthur J.

2004-01-01

A calibration process is presented that uses optical measurements alone to calibrate a neural-net based NDE method. The method itself detects small changes in the vibration mode shapes of structures. The optics-only calibration process confirms previous work that the sensitivity to vibration-amplitude changes can be as small as 10 nanometers. A more practical value in an NDE service laboratory is shown to be 50 nanometers. Both model-generated and experimental calibrations are demonstrated using two implementations of the calibration technique. The implementations are based on previously published demonstrations of the NDE method and an alternative calibration procedure that depends on comparing neural-net and point sensor measurements. The optics-only calibration method, unlike the alternative method, does not require modifications of the structure being tested or the creation of calibration objects. The calibration process can be used to test improvements in the NDE process and to develop a vibration-mode-independence of damagedetection sensitivity. The calibration effort was intended to support NASA s objective to promote safety in the operations of ground test facilities or aviation safety, in general, by allowing the detection of the gradual onset of structural changes and damage.

Who We Are: Today's Students Speak Out

ERIC Educational Resources Information Center

Blandford, Ayoka

2012-01-01

Today's students have been nicknamed the "Digital Generation," "Millennials," "Net Generation" and "Generation Next." They are frequently identified by their technological prowess and seem to work well with multiple stimuli (for example, designing a web site while listening to iTunes and responding to texts). While many research studies have been…

Hydrodynamic characteristics of knotted and knotless purse seine netting panels as determined in a flume tank

PubMed Central

Tang, Hao; Xu, Liuxiong; Hu, Fuxiang

2018-01-01

Nylon (PA) netting is widely used in purse seines and other fishing gears due to its high strength and good sinking performance. However, hydrodynamic properties of nylon netting of different characteristics are poorly understood. This study investigated hydrodynamic characteristics of nylon netting of different knot types and solidity ratios under different attack angles and flow velocities. It was found that the hydrodynamic coefficient of netting panels was related to Reynolds number, solidity ratio, attack angle, knot type and twine construction. The solidity ratio was found to positively correlate with drag coefficient when the netting was normal to the flow (CD90), but not the case when the netting was parallel to the flow (CD0). For netting panels inclined to the flow, the inclined drag coefficient had a negative relationship with the solidity ratio for attack angles between 0° and 50°, but a positive relationship for attack angles between 50° and 90°. The lift coefficient increased with the attack angle, reaching the culminating point at an attack angle of 50°, before subsequent decline. We found that the drag generated by knot accounted for 15–25% of total drag, and the knotted netting with higher solidity ratio exhibited a greater CD0, but it was not the case for the knotless netting. Compared to knotless polyethylene (PE) netting, the drag coefficients of knotless PA netting were dominant at higher Reynolds number (Re>2200). PMID:29420569

Hydrodynamic characteristics of knotted and knotless purse seine netting panels as determined in a flume tank.

PubMed

Tang, Hao; Xu, Liuxiong; Hu, Fuxiang

2018-01-01

Nylon (PA) netting is widely used in purse seines and other fishing gears due to its high strength and good sinking performance. However, hydrodynamic properties of nylon netting of different characteristics are poorly understood. This study investigated hydrodynamic characteristics of nylon netting of different knot types and solidity ratios under different attack angles and flow velocities. It was found that the hydrodynamic coefficient of netting panels was related to Reynolds number, solidity ratio, attack angle, knot type and twine construction. The solidity ratio was found to positively correlate with drag coefficient when the netting was normal to the flow (CD90), but not the case when the netting was parallel to the flow (CD0). For netting panels inclined to the flow, the inclined drag coefficient had a negative relationship with the solidity ratio for attack angles between 0° and 50°, but a positive relationship for attack angles between 50° and 90°. The lift coefficient increased with the attack angle, reaching the culminating point at an attack angle of 50°, before subsequent decline. We found that the drag generated by knot accounted for 15-25% of total drag, and the knotted netting with higher solidity ratio exhibited a greater CD0, but it was not the case for the knotless netting. Compared to knotless polyethylene (PE) netting, the drag coefficients of knotless PA netting were dominant at higher Reynolds number (Re>2200).

A Climate Statistics Tool and Data Repository

NASA Astrophysics Data System (ADS)

Wang, J.; Kotamarthi, V. R.; Kuiper, J. A.; Orr, A.

2017-12-01

Researchers at Argonne National Laboratory and collaborating organizations have generated regional scale, dynamically downscaled climate model output using Weather Research and Forecasting (WRF) version 3.3.1 at a 12km horizontal spatial resolution over much of North America. The WRF model is driven by boundary conditions obtained from three independent global scale climate models and two different future greenhouse gas emission scenarios, named representative concentration pathways (RCPs). The repository of results has a temporal resolution of three hours for all the simulations, includes more than 50 variables, is stored in Network Common Data Form (NetCDF) files, and the data volume is nearly 600Tb. A condensed 800Gb set of NetCDF files were made for selected variables most useful for climate-related planning, including daily precipitation, relative humidity, solar radiation, maximum temperature, minimum temperature, and wind. The WRF model simulations are conducted for three 10-year time periods (1995-2004, 2045-2054, and 2085-2094), and two future scenarios RCP4.5 and RCP8.5). An open-source tool was coded using Python 2.7.8 and ESRI ArcGIS 10.3.1 programming libraries to parse the NetCDF files, compute summary statistics, and output results as GIS layers. Eight sets of summary statistics were generated as examples for the contiguous U.S. states and much of Alaska, including number of days over 90°F, number of days with a heat index over 90°F, heat waves, monthly and annual precipitation, drought, extreme precipitation, multi-model averages, and model bias. This paper will provide an overview of the project to generate the main and condensed data repositories, describe the Python tool and how to use it, present the GIS results of the computed examples, and discuss some of the ways they can be used for planning. The condensed climate data, Python tool, computed GIS results, and documentation of the work are shared on the Internet.

Software Tool Integrating Data Flow Diagrams and Petri Nets

NASA Technical Reports Server (NTRS)

Thronesbery, Carroll; Tavana, Madjid

2010-01-01

Data Flow Diagram - Petri Net (DFPN) is a software tool for analyzing other software to be developed. The full name of this program reflects its design, which combines the benefit of data-flow diagrams (which are typically favored by software analysts) with the power and precision of Petri-net models, without requiring specialized Petri-net training. (A Petri net is a particular type of directed graph, a description of which would exceed the scope of this article.) DFPN assists a software analyst in drawing and specifying a data-flow diagram, then translates the diagram into a Petri net, then enables graphical tracing of execution paths through the Petri net for verification, by the end user, of the properties of the software to be developed. In comparison with prior means of verifying the properties of software to be developed, DFPN makes verification by the end user more nearly certain, thereby making it easier to identify and correct misconceptions earlier in the development process, when correction is less expensive. After the verification by the end user, DFPN generates a printable system specification in the form of descriptions of processes and data.

Prediction of Disease Causing Non-Synonymous SNPs by the Artificial Neural Network Predictor NetDiseaseSNP

PubMed Central

Johansen, Morten Bo; Izarzugaza, Jose M. G.; Brunak, Søren; Petersen, Thomas Nordahl; Gupta, Ramneek

2013-01-01

We have developed a sequence conservation-based artificial neural network predictor called NetDiseaseSNP which classifies nsSNPs as disease-causing or neutral. Our method uses the excellent alignment generation algorithm of SIFT to identify related sequences and a combination of 31 features assessing sequence conservation and the predicted surface accessibility to produce a single score which can be used to rank nsSNPs based on their potential to cause disease. NetDiseaseSNP classifies successfully disease-causing and neutral mutations. In addition, we show that NetDiseaseSNP discriminates cancer driver and passenger mutations satisfactorily. Our method outperforms other state-of-the-art methods on several disease/neutral datasets as well as on cancer driver/passenger mutation datasets and can thus be used to pinpoint and prioritize plausible disease candidates among nsSNPs for further investigation. NetDiseaseSNP is publicly available as an online tool as well as a web service: http://www.cbs.dtu.dk/services/NetDiseaseSNP PMID:23935863

Neutrophil Extracellular Traps: Formation and Involvement in Disease Progression.

PubMed

Kumar, Sanni; Gupta, Ena; Kaushik, Sanket; Jyoti, Anupam

2018-06-01

Neutrophils are the forerunner in innate immunity by defending the host organisms against infectious pathogens. During such process, neutrophils reach the site of inflammation/infection and eliminate the pathogens by phagocytosis as well as by forming the neutrophil extracellular traps (NETs). NETs trap and eradicate a number of microbes including bacteria, fungi, protozoa, viruses. NETs consist of DNA which is decorated with histones and granular proteins such as neutrophil elastase (NE), gelatinase, myeloperoxidase. NETosis (a process of NETs formation) is also involved in many inflammatory and autoimmune disorders with a major contribution to acute respiratory distress syndrome, sepsis, cystic fibrosis, periodontitis. Hyper NETosis or ineffective clearance of NETs would likely increase the risk of auto-antibody generation against NETs components and contribution in auto-inflammatory diseases. The purpose of this review is intended to highlight the molecular mechanisms of NETosis and its antimicrobial effect. Furthermore, a current status of NETosis in the pathogenesis of inflammatory and autoimmune disorders has been reviewed for better understanding.

NetGen: a novel network-based probabilistic generative model for gene set functional enrichment analysis.

PubMed

Sun, Duanchen; Liu, Yinliang; Zhang, Xiang-Sun; Wu, Ling-Yun

2017-09-21

High-throughput experimental techniques have been dramatically improved and widely applied in the past decades. However, biological interpretation of the high-throughput experimental results, such as differential expression gene sets derived from microarray or RNA-seq experiments, is still a challenging task. Gene Ontology (GO) is commonly used in the functional enrichment studies. The GO terms identified via current functional enrichment analysis tools often contain direct parent or descendant terms in the GO hierarchical structure. Highly redundant terms make users difficult to analyze the underlying biological processes. In this paper, a novel network-based probabilistic generative model, NetGen, was proposed to perform the functional enrichment analysis. An additional protein-protein interaction (PPI) network was explicitly used to assist the identification of significantly enriched GO terms. NetGen achieved a superior performance than the existing methods in the simulation studies. The effectiveness of NetGen was explored further on four real datasets. Notably, several GO terms which were not directly linked with the active gene list for each disease were identified. These terms were closely related to the corresponding diseases when accessed to the curated literatures. NetGen has been implemented in the R package CopTea publicly available at GitHub ( http://github.com/wulingyun/CopTea/ ). Our procedure leads to a more reasonable and interpretable result of the functional enrichment analysis. As a novel term combination-based functional enrichment analysis method, NetGen is complementary to current individual term-based methods, and can help to explore the underlying pathogenesis of complex diseases.

CoryneRegNet: an ontology-based data warehouse of corynebacterial transcription factors and regulatory networks.

PubMed

Baumbach, Jan; Brinkrolf, Karina; Czaja, Lisa F; Rahmann, Sven; Tauch, Andreas

2006-02-14

The application of DNA microarray technology in post-genomic analysis of bacterial genome sequences has allowed the generation of huge amounts of data related to regulatory networks. This data along with literature-derived knowledge on regulation of gene expression has opened the way for genome-wide reconstruction of transcriptional regulatory networks. These large-scale reconstructions can be converted into in silico models of bacterial cells that allow a systematic analysis of network behavior in response to changing environmental conditions. CoryneRegNet was designed to facilitate the genome-wide reconstruction of transcriptional regulatory networks of corynebacteria relevant in biotechnology and human medicine. During the import and integration process of data derived from experimental studies or literature knowledge CoryneRegNet generates links to genome annotations, to identified transcription factors and to the corresponding cis-regulatory elements. CoryneRegNet is based on a multi-layered, hierarchical and modular concept of transcriptional regulation and was implemented by using the relational database management system MySQL and an ontology-based data structure. Reconstructed regulatory networks can be visualized by using the yFiles JAVA graph library. As an application example of CoryneRegNet, we have reconstructed the global transcriptional regulation of a cellular module involved in SOS and stress response of corynebacteria. CoryneRegNet is an ontology-based data warehouse that allows a pertinent data management of regulatory interactions along with the genome-scale reconstruction of transcriptional regulatory networks. These models can further be combined with metabolic networks to build integrated models of cellular function including both metabolism and its transcriptional regulation.

NetGENgagement: How the Net Generation College Student Uses Social Media in Academic and Social College Experiences

ERIC Educational Resources Information Center

Sesterhenn, Shannon Marie

2012-01-01

The landscape of higher education is constantly evolving. Similar to a wave that washes ashore and transforms the shoreline, the same is occurring with higher education and its "shoreline". With the influx of technology and social media on college and university campuses, higher education institutions have had to grapple with whether or…

Cost Of Compliance On Munitions Consolidation From Lualualei To West Loch

DTIC Science & Technology

2017-12-01

from the perspective of the Department of Defense in order to capture all costs and benefits associated with the Army and Navy, the main stakeholders...weaknesses of the available alternative options. The model identifies tangible costs and benefits to estimate a net present value for each option. To...the robustness of the average net present value and to show the probability of net costs exceeding the net benefits . The analysis conducted in this

NETS - A NEURAL NETWORK DEVELOPMENT TOOL, VERSION 3.0 (MACINTOSH VERSION)

NASA Technical Reports Server (NTRS)

Phillips, T. A.

1994-01-01

NETS, A Tool for the Development and Evaluation of Neural Networks, provides a simulation of Neural Network algorithms plus an environment for developing such algorithms. Neural Networks are a class of systems modeled after the human brain. Artificial Neural Networks are formed from hundreds or thousands of simulated neurons, connected to each other in a manner similar to brain neurons. Problems which involve pattern matching readily fit the class of problems which NETS is designed to solve. NETS uses the back propagation learning method for all of the networks which it creates. The nodes of a network are usually grouped together into clumps called layers. Generally, a network will have an input layer through which the various environment stimuli are presented to the network, and an output layer for determining the network's response. The number of nodes in these two layers is usually tied to some features of the problem being solved. Other layers, which form intermediate stops between the input and output layers, are called hidden layers. NETS allows the user to customize the patterns of connections between layers of a network. NETS also provides features for saving the weight values of a network during the learning process, which allows for more precise control over the learning process. NETS is an interpreter. Its method of execution is the familiar "read-evaluate-print" loop found in interpreted languages such as BASIC and LISP. The user is presented with a prompt which is the simulator's way of asking for input. After a command is issued, NETS will attempt to evaluate the command, which may produce more prompts requesting specific information or an error if the command is not understood. The typical process involved when using NETS consists of translating the problem into a format which uses input/output pairs, designing a network configuration for the problem, and finally training the network with input/output pairs until an acceptable error is reached. NETS allows the user to generate C code to implement the network loaded into the system. This permits the placement of networks as components, or subroutines, in other systems. In short, once a network performs satisfactorily, the Generate C Code option provides the means for creating a program separate from NETS to run the network. Other features: files may be stored in binary or ASCII format; multiple input propagation is permitted; bias values may be included; capability to scale data without writing scaling code; quick interactive testing of network from the main menu; and several options that allow the user to manipulate learning efficiency. NETS is written in ANSI standard C language to be machine independent. The Macintosh version (MSC-22108) includes code for both a graphical user interface version and a command line interface version. The machine independent version (MSC-21588) only includes code for the command line interface version of NETS 3.0. The Macintosh version requires a Macintosh II series computer and has been successfully implemented under System 7. Four executables are included on these diskettes, two for floating point operations and two for integer arithmetic. It requires Think C 5.0 to compile. A minimum of 1Mb of RAM is required for execution. Sample input files and executables for both the command line version and the Macintosh user interface version are provided on the distribution medium. The Macintosh version is available on a set of three 3.5 inch 800K Macintosh format diskettes. The machine independent version has been successfully implemented on an IBM PC series compatible running MS-DOS, a DEC VAX running VMS, a SunIPC running SunOS, and a CRAY Y-MP running UNICOS. Two executables for the IBM PC version are included on the MS-DOS distribution media, one compiled for floating point operations and one for integer arithmetic. The machine independent version is available on a set of three 5.25 inch 360K MS-DOS format diskettes (standard distribution medium) or a .25 inch streaming magnetic tape cartridge in UNIX tar format. NETS was developed in 1989 and updated in 1992. IBM PC is a registered trademark of International Business Machines. MS-DOS is a registered trademark of Microsoft Corporation. DEC, VAX, and VMS are trademarks of Digital Equipment Corporation. SunIPC and SunOS are trademarks of Sun Microsystems, Inc. CRAY Y-MP and UNICOS are trademarks of Cray Research, Inc.

NETS - A NEURAL NETWORK DEVELOPMENT TOOL, VERSION 3.0 (MACHINE INDEPENDENT VERSION)

NASA Technical Reports Server (NTRS)

Baffes, P. T.

1994-01-01

NETS, A Tool for the Development and Evaluation of Neural Networks, provides a simulation of Neural Network algorithms plus an environment for developing such algorithms. Neural Networks are a class of systems modeled after the human brain. Artificial Neural Networks are formed from hundreds or thousands of simulated neurons, connected to each other in a manner similar to brain neurons. Problems which involve pattern matching readily fit the class of problems which NETS is designed to solve. NETS uses the back propagation learning method for all of the networks which it creates. The nodes of a network are usually grouped together into clumps called layers. Generally, a network will have an input layer through which the various environment stimuli are presented to the network, and an output layer for determining the network's response. The number of nodes in these two layers is usually tied to some features of the problem being solved. Other layers, which form intermediate stops between the input and output layers, are called hidden layers. NETS allows the user to customize the patterns of connections between layers of a network. NETS also provides features for saving the weight values of a network during the learning process, which allows for more precise control over the learning process. NETS is an interpreter. Its method of execution is the familiar "read-evaluate-print" loop found in interpreted languages such as BASIC and LISP. The user is presented with a prompt which is the simulator's way of asking for input. After a command is issued, NETS will attempt to evaluate the command, which may produce more prompts requesting specific information or an error if the command is not understood. The typical process involved when using NETS consists of translating the problem into a format which uses input/output pairs, designing a network configuration for the problem, and finally training the network with input/output pairs until an acceptable error is reached. NETS allows the user to generate C code to implement the network loaded into the system. This permits the placement of networks as components, or subroutines, in other systems. In short, once a network performs satisfactorily, the Generate C Code option provides the means for creating a program separate from NETS to run the network. Other features: files may be stored in binary or ASCII format; multiple input propagation is permitted; bias values may be included; capability to scale data without writing scaling code; quick interactive testing of network from the main menu; and several options that allow the user to manipulate learning efficiency. NETS is written in ANSI standard C language to be machine independent. The Macintosh version (MSC-22108) includes code for both a graphical user interface version and a command line interface version. The machine independent version (MSC-21588) only includes code for the command line interface version of NETS 3.0. The Macintosh version requires a Macintosh II series computer and has been successfully implemented under System 7. Four executables are included on these diskettes, two for floating point operations and two for integer arithmetic. It requires Think C 5.0 to compile. A minimum of 1Mb of RAM is required for execution. Sample input files and executables for both the command line version and the Macintosh user interface version are provided on the distribution medium. The Macintosh version is available on a set of three 3.5 inch 800K Macintosh format diskettes. The machine independent version has been successfully implemented on an IBM PC series compatible running MS-DOS, a DEC VAX running VMS, a SunIPC running SunOS, and a CRAY Y-MP running UNICOS. Two executables for the IBM PC version are included on the MS-DOS distribution media, one compiled for floating point operations and one for integer arithmetic. The machine independent version is available on a set of three 5.25 inch 360K MS-DOS format diskettes (standard distribution medium) or a .25 inch streaming magnetic tape cartridge in UNIX tar format. NETS was developed in 1989 and updated in 1992. IBM PC is a registered trademark of International Business Machines. MS-DOS is a registered trademark of Microsoft Corporation. DEC, VAX, and VMS are trademarks of Digital Equipment Corporation. SunIPC and SunOS are trademarks of Sun Microsystems, Inc. CRAY Y-MP and UNICOS are trademarks of Cray Research, Inc.

Classical workflow nets and workflow nets with reset arcs: using Lyapunov stability for soundness verification

NASA Astrophysics Data System (ADS)

Clempner, Julio B.

2017-01-01

This paper presents a novel analytical method for soundness verification of workflow nets and reset workflow nets, using the well-known stability results of Lyapunov for Petri nets. We also prove that the soundness property is decidable for workflow nets and reset workflow nets. In addition, we provide evidence of several outcomes related with properties such as boundedness, liveness, reversibility and blocking using stability. Our approach is validated theoretically and by a numerical example related to traffic signal-control synchronisation.

Geometric pumping in autophoretic channels.

PubMed

Michelin, Sébastien; Montenegro-Johnson, Thomas D; De Canio, Gabriele; Lobato-Dauzier, Nicolas; Lauga, Eric

2015-08-07

Many microfluidic devices use macroscopic pressure differentials to overcome viscous friction and generate flows in microchannels. In this work, we investigate how the chemical and geometric properties of the channel walls can drive a net flow by exploiting the autophoretic slip flows induced along active walls by local concentration gradients of a solute species. We show that chemical patterning of the wall is not required to generate and control a net flux within the channel, rather channel geometry alone is sufficient. Using numerical simulations, we determine how geometric characteristics of the wall influence channel flow rate, and confirm our results analytically in the asymptotic limit of lubrication theory.

Heritage, Image and Identity: The Evolution of USAF Leadership

DTIC Science & Technology

2011-02-16

up-in-coming “ Generation Z ” (also known as the “Net or Digital Generation”), which is the most connected and high-tech generation ever seen. 40...for future RPA warrior leaders. 43 The USAF has already set the ground work to position “ Generation Z ” RPA pilots for future senior leadership

Today's Millennial Generation: A Look Ahead to the Future They Create

ERIC Educational Resources Information Center

Nikirk, Martin

2009-01-01

It's 2009: The current millennial generation, the i-Kids, the "Digital Natives," the Net Generation students are now approximately ages 8 to 27. Many of these students are entering their years of career exploration while others are actively involved in career and technical education (CTE) programs in school or college. The millennial…

A simple stochastic weather generator for ecological modeling

Treesearch

A.G. Birt; M.R. Valdez-Vivas; R.M. Feldman; C.W. Lafon; D. Cairns; R.N. Coulson; M. Tchakerian; W. Xi; Jim Guldin

2010-01-01

Stochastic weather generators are useful tools for exploring the relationship between organisms and their environment. This paper describes a simple weather generator that can be used in ecological modeling projects. We provide a detailed description of methodology, and links to full C++ source code (http://weathergen.sourceforge.net) required to implement or modify...

Considerations of net present value in policy making regarding diagnostic and therapeutic technologies.

PubMed

Califf, Robert M; Rasiel, Emma B; Schulman, Kevin A

2008-11-01

The pharmaceutical and medical device industries function in a business environment in which shareholders expect companies to optimize profit within legal and ethical standards. A fundamental tool used to optimize decision making is the net present value calculation, which estimates the current value of cash flows relating to an investment. We examined 3 prototypical research investment decisions that have been the source of public scrutiny to illustrate how policy decisions can be better understood when their impact on societally desirable investments by industry are viewed from the standpoint of their impact on net present value. In the case of direct, comparative clinical trials, a simple net present value calculation provides insight into why companies eschew such investments. In the case of pediatric clinical trials, the Pediatric Extension Rule changed the net present value calculation from unattractive to potentially very attractive by allowing patent extensions; thus, the dramatic increase in pediatric clinical trials can be explained by the financial return on investment. In the case of products for small markets, the fixed costs of development make this option financially unattractive. Policy decisions can be better understood when their impact on societally desirable investments by the pharmaceutical and medical device industries are viewed from the standpoint of their impact on net present value.

Climatic Forecasting of Net Infiltration at Yucca Montain Using Analogue Meteororological Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

B. Faybishenko

At Yucca Mountain, Nevada, future changes in climatic conditions will most likely alter net infiltration, or the drainage below the bottom of the evapotranspiration zone within the soil profile or flow across the interface between soil and the densely welded part of the Tiva Canyon Tuff. The objectives of this paper are to: (a) develop a semi-empirical model and forecast average net infiltration rates, using the limited meteorological data from analogue meteorological stations, for interglacial (present day), and future monsoon, glacial transition, and glacial climates over the Yucca Mountain region, and (b) corroborate the computed net-infiltration rates by comparing themmore » with the empirically and numerically determined groundwater recharge and percolation rates through the unsaturated zone from published data. In this paper, the author presents an approach for calculations of net infiltration, aridity, and precipitation-effectiveness indices, using a modified Budyko's water-balance model, with reference-surface potential evapotranspiration determined from the radiation-based Penman (1948) formula. Results of calculations show that net infiltration rates are expected to generally increase from the present-day climate to monsoon climate, to glacial transition climate, and then to the glacial climate. The forecasting results indicate the overlap between the ranges of net infiltration for different climates. For example, the mean glacial net-infiltration rate corresponds to the upper-bound glacial transition net infiltration, and the lower-bound glacial net infiltration corresponds to the glacial transition mean net infiltration. Forecasting of net infiltration for different climate states is subject to numerous uncertainties-associated with selecting climate analogue sites, using relatively short analogue meteorological records, neglecting the effects of vegetation and surface runoff and runon on a local scale, as well as possible anthropogenic climate changes.« less

Neural networks for structural design - An integrated system implementation

NASA Technical Reports Server (NTRS)

Berke, Laszlo; Hafez, Wassim; Pao, Yoh-Han

1992-01-01

The development of powerful automated procedures to aid the creative designer is becoming increasingly critical for complex design tasks. In the work described here Artificial Neural Nets are applied to acquire structural analysis and optimization domain expertise. Based on initial instructions from the user an automated procedure generates random instances of structural analysis and/or optimization 'experiences' that cover a desired domain. It extracts training patterns from the created instances, constructs and trains an appropriate network architecture and checks the accuracy of net predictions. The final product is a trained neural net that can estimate analysis and/or optimization results instantaneously.

Spontaneous Wave Generation from Submesoscale Fronts and Filaments

NASA Astrophysics Data System (ADS)

Shakespeare, C. J.; Hogg, A.

2016-02-01

Submesoscale features such as eddies, fronts, jets and filaments can be significant sources of spontaneous wave generation at the ocean surface. Unlike near-inertial waves forced by winds, these spontaneous waves are typically of higher frequency and can propagate through the thermocline, whereupon they break and drive mixing in the ocean interior. Here we investigate the spontaneous generation, propagation and subsequent breaking of these waves using a combination of theory and submesoscale resolving numerical models. The mechanism of generation is nearly identical to that of lee waves where flow is deflected over a rigid obstacle on the sea floor. Here, very sharp fronts and filaments of order 100m width moving in the submesoscale surface flow generate "surface lee waves" by presenting an obstacle to the surrounding stratified fluid. Using our numerical model we quantify the net downward wave energy flux from the surface, and where it is dissipated in the water column. Our results suggest an alternative to the classical paradigm where the energy associated with mixing in the ocean interior is sourced from bottom-generated lee waves.

ANTARES and KM3NeT programs for the supernova neutrino detection

NASA Astrophysics Data System (ADS)

Kulikovskiy, Vladimir

2017-02-01

The currently working ANTARES neutrino telescope has capabilities to detect neutrinos produced in astrophysical transient sources. Neutrino alerts are regularly generated to trigger multi-wavelength observatories. Potential sources include gamma-ray bursts, core-collapse supernovae, and flaring active galactic nuclei. In particular, the neutrino detection together with the multi-wavelength observations may reveal hidden jets in the supernova explosions. Supernovae remnants are currently the most promising acceleration sites of the cosmic rays in our Galaxy. The neutrino emission is expected during the cosmic ray interaction with the surrounding matter. The neutrino telescopes in the Northern hemisphere have excellent visibility to the most of the galactic supernovae remnants. Recent results on the search for point-sources with the ANTARES detector and the prospects for the future KM3NeT detector are presented. Although ANTARES and KM3NeT detectors are mainly designed for high energy neutrino detection, the MeV neutrino signal from the supernova can be identified as a simultaneous increase of the counting rate of the optical modules in the detector. The noise from the optical background due to 40K decay in the sea water and the bioluminescence can be significantly reduced by using nanosecond coincidences between the nearby placed photomultipliers. This technique has been tested with the ANTARES storeys, each one consisting of three 10-inch photomultipliers, and it is further optimized for the KM3NeT telescope where the directional optical modules containing 31 3-inch photomultipliers provide very promising expectations.

Medical Situational Awareness in Theater Advanced Concept Technology Demonstration Project Proposal

DTIC Science & Technology

2004-06-01

making it an impossible task to sort, understand , and generate actionable knowledge within operational timeframes. Medical Situational Awareness in...need for greater medical situation awareness in theater and for greater integration of theater medical information into the net-centric rapid...There is a need for greater Medical Situation Awareness in theater and for greater integration of theater medical information into the ForceNet

Fuzzy net present valuation based on risk assessment of Malaysian infrastructure

NASA Astrophysics Data System (ADS)

Shaffie, Siti Salihah; Jaaman, Saiful Hafizah; Mohamad, Daud

2017-04-01

In recent years, built-operate-transfer (BOT) projects have profoundly been accepted under project financing for infrastructure developments in many countries. It requires high financing and involves complex mutual risk. The assessment of the risks is vital to avert huge financial loss. Net present value is widely applied to BOT project where the uncertainties in cash flows are deemed to be deterministic values. This study proposed a fuzzy net present value model taking consideration the assessment of risks from the BOT project. The proposed model is adopted to provide more flexible net present valuation of the project. It is shown and proven that the improved fuzzy cash flow model will provide a valuation that is closed to the real value of the project.

SkyNet: A Modular Nuclear Reaction Network Library

NASA Astrophysics Data System (ADS)

Lippuner, Jonas; Roberts, Luke F.

2017-12-01

Almost all of the elements heavier than hydrogen that are present in our solar system were produced by nuclear burning processes either in the early universe or at some point in the life cycle of stars. In all of these environments, there are dozens to thousands of nuclear species that interact with each other to produce successively heavier elements. In this paper, we present SkyNet, a new general-purpose nuclear reaction network that evolves the abundances of nuclear species under the influence of nuclear reactions. SkyNet can be used to compute the nucleosynthesis evolution in all astrophysical scenarios where nucleosynthesis occurs. SkyNet is free and open source, and aims to be easy to use and flexible. Any list of isotopes can be evolved, and SkyNet supports different types of nuclear reactions. SkyNet is modular so that new or existing physics, like nuclear reactions or equations of state, can easily be added or modified. Here, we present in detail the physics implemented in SkyNet with a focus on a self-consistent transition to and from nuclear statistical equilibrium to non-equilibrium nuclear burning, our implementation of electron screening, and coupling of the network to an equation of state. We also present comprehensive code tests and comparisons with existing nuclear reaction networks. We find that SkyNet agrees with published results and other codes to an accuracy of a few percent. Discrepancies, where they exist, can be traced to differences in the physics implementations.

Capturing birds with mist nets: A review

USGS Publications Warehouse

Keyes, B.E.; Grue, C.E.

1982-01-01

Herein we have tried to provide a comprehensive review of mist-netting techniques suitable for both novice and experienced netters. General mist-netting procedures and modifications developed by netters for particular bird species and habitats are included. Factors which influence capture success, including site selection, net specifications and placement, weather, and time of day, are discussed. Guidelines are presented for the care of netted birds and the use of mist-net data in the study of bird communities. The advantages of the use of mist nets over other methods of capturing birds are also discussed.

Breastfeeding is positively associated with child intelligence even net of parental IQ.

PubMed

Kanazawa, Satoshi

2015-12-01

Some previous reviews conclude that breastfeeding is not significantly associated with increased intelligence in children once mother's IQ is statistically controlled. The conclusion may potentially have both theoretical and methodological problems. The National Child Development Study allows the examination of the effect of breastfeeding on intelligence in two consecutive generations of British children. The analysis of the first generation shows that the effect of breastfeeding on intelligence increases from Age 7 to 16. The analysis of the second generation shows that each month of breastfeeding, net of parental IQ and other potential confounds, is associated with an increase of .16 IQ points. Further analyses suggest that some previous studies may have failed to uncover the effect of breastfeeding on child intelligence because of their reliance on one IQ test. (c) 2015 APA, all rights reserved).

Analytical results for total-digestions, EPA-1312 leach, and net acid production for twenty-three abandoned metal-mining related wastes in the Boulder River watershed, northern Jefferson County, Montana

USGS Publications Warehouse

Fey, David L.; Desborough, George A.; Finney, Christopher J.

2000-01-01

IntroductionMetal-mining related wastes in the Boulder River basin study area in northern Jefferson County, Montana, have been implicated in their detrimental effects on water quality with regard to acid generation and toxic-metal solubilization during snow melt and storm water runoff events. This degradation of water quality is defined chiefly by the “Class 1 Aquatic Life Standards” that give limits for certain dissolved metal concentrations according to water alkalinity.Veins enriched in base- and precious metals were explored and mined in the Basin, Cataract Creek, and High Ore Creek drainages over a period of more than 70 years. Extracted minerals included galena, sphalerite, pyrite, chalcopyrite, tetrahedrite and arsenopyrite. Most of the metal-mining wastes in the study area were identified and described by the Montana Bureau of Mines and Geology. In 1997, the U.S. Geological Survey collected 20 composite samples of mine-dump or tailings waste from ten sites in the Basin and Cataract Creek drainages, and two samples from one site in the High Ore Creek drainage. Desborough and Fey presented data concerning acid generation potential, mineralogy, concentrations of certain metals by energy-dispersive X-ray fluorescence (EDXRF), and trace-element leachability of mine and exploration wastes from the ten sites of the Basin and Cataract Creek drainages. The present report presents total-digestion major- and trace-element analyses, net acid production (NAP), and results from the EPA-1312 synthetic precipitation leach procedure (SPLP) performed on the same composite samples from the ten sites from the Basin and Cataract Creek drainages, and two composite samples from the site in the High Ore Creek drainage.

Beyond Reason: Emotion

NASA Astrophysics Data System (ADS)

Suárez Araujo, Carmen Paz; Barahona da Fonseca, Isabel; Barahona da Fonseca, José; Simões da Fonseca, J.

2004-08-01

A theoretical approach that aims to the identification of information processing that may be responsible for emotional dimensions of subjective experience is studied as an initial step in the construction of a neural net model of affective dimensions of psychological experiences. In this paper it is suggested that a way of orientated recombination of attributes can be present not only in the perceptive processing but also in cognitive ones. We will present an analysis of the most important emotion theories, we show their neural organization and we propose the neural computation approach as an appropriate framework for generating knowledge about the neural base of emotional experience. Finally, in this study we present a scheme corresponding to framework to design a computational neural multi-system for Emotion (CONEMSE).

A Bio-Economic Case Study of Canadian Honey Bee (Hymenoptera: Apidae) Colonies: Marker-Assisted Selection (MAS) in Queen Breeding Affects Beekeeper Profits.

PubMed

Bixby, Miriam; Baylis, Kathy; Hoover, Shelley E; Currie, Rob W; Melathopoulos, Andony P; Pernal, Stephen F; Foster, Leonard J; Guarna, M Marta

2017-06-01

Over the past decade in North America and Europe, winter losses of honey bee (Hymenoptera: Apidae) colonies have increased dramatically. Scientific consensus attributes these losses to multifactorial causes including altered parasite and pathogen profiles, lack of proper nutrition due to agricultural monocultures, exposure to pesticides, management, and weather. One method to reduce colony loss and increase productivity is through selective breeding of queens to produce disease-, pathogen-, and mite-resistant stock. Historically, the only method for identifying desirable traits in honey bees to improve breeding was through observation of bee behavior. A team of Canadian scientists have recently identified markers in bee antennae that correspond to behavioral traits in bees and can be tested for in a laboratory. These scientists have demonstrated that this marker-assisted selection (MAS) can be used to produce hygienic, pathogen-resistant honey bee colonies. Based on this research, we present a beekeeping case study where a beekeeper's profit function is used to evaluate the economic impact of adopting colonies selected for hygienic behavior using MAS into an apiary. Our results show a net profit gain from an MAS colony of between 2% and 5% when Varroa mites are effectively treated. In the case of ineffective treatment, MAS generates a net profit benefit of between 9% and 96% depending on the Varroa load. When a Varroa mite population has developed some treatment resistance, we show that MAS colonies generate a net profit gain of between 8% and 112% depending on the Varroa load and degree of treatment resistance. © The Authors 2017. Published by Oxford University Press on behalf of Entomological Society of America.

Energy Balance of Rural Ecosystems In India

NASA Astrophysics Data System (ADS)

Chhabra, A.; Madhava Rao, V.; Hermon, R. R.; Garg, A.; Nag, T.; Bhaskara Rao, N.; Sharma, A.; Parihar, J. S.

2014-11-01

India is predominantly an agricultural and rural country. Across the country, the villages vary in geographical location, area, human and livestock population, availability of resources, agricultural practices, livelihood patterns etc. This study presents an estimation of net energy balance resulting from primary production vis-a-vis energy consumption through various components in a "Rural Ecosystem". Seven sites located in different agroclimatic regions of India were studied. An end use energy accounting "Rural Energy Balance Model" is developed for input-output analysis of various energy flows of production, consumption, import and export through various components of crop, trees outside forest plantations, livestock, rural households, industry or trade within the village system boundary. An integrated approach using field, ancillary, GIS and high resolution IRS-P6 Resourcesat-2 LISS IV data is adopted for generation of various model inputs. The primary and secondary field data collection of various energy uses at household and village level were carried out using structured schedules and questionnaires. High resolution multi-temporal Resourcesat-2 LISS IV data (2013-14) was used for generating landuse/landcover maps and estimation of above-ground Trees Outside Forests phytomass. The model inputs were converted to energy equivalents using country-specific energy conversion factors. A comprehensive geotagged database of sampled households and available resources at each study site was also developed in ArcGIS framework. Across the study sites, the estimated net energy balance ranged from -18.8 Terra Joules (TJ) in a high energy consuming Hodka village, Gujarat to 224.7 TJ in an agriculture, aquaculture and plantation intensive Kollaparru village, Andhra Pradesh. The results indicate that the net energy balance of a Rural Ecosystem is largely driven by primary production through crops and natural vegetation. This study provides a significant insight to policy relevant recommendations for Energy Sustainable Rural India.

Effects of nearshore recharge on groundwater interactions with a lake in mantled karst terrain

USGS Publications Warehouse

Lee, Terrie M.

2000-01-01

The recharge and discharge of groundwater were investigated for a lake basin in the mantled karst terrain of central Florida to determine the relative importance of transient groundwater inflow to the lake water budget. Variably saturated groundwater flow modeling simulated water table responses observed beneath two hillsides radiating outward from the groundwater flow‐through lake. Modeling results indicated that transient water table mounding and groundwater flow reversals in the nearshore region following large daily rainfall events generated most of the net groundwater inflow to the lake. Simulated daily groundwater inflow was greatest following water table mounding near the lake, not following subsequent peaks in the water level of upper basin wells. Transient mounding generated net groundwater inflow to the lake, that is, groundwater inflow in excess of the outflow occurring through the deeper lake bottom. The timing of the modeled net groundwater inflow agreed with an independent lake water budget; however, the quantity was considerably less than the budget‐derived value.

Neutrophil extracellular traps enriched in oxidized mitochondrial DNA are interferogenic and contribute to lupus-like disease

PubMed Central

Lood, Christian; Blanco, Luz P.; Purmalek, Monica M.; Carmona-Rivera, Carmelo; De Ravin, Suk S.; Smith, Carolyne K.; Malech, Harry L.; Ledbetter, Jeffrey A.; Elkon, Keith B.; Kaplan, Mariana J.

2015-01-01

Neutrophil extracellular traps (NETs) are implicated in autoimmunity but how they are generated and their roles in sterile inflammation remain unclear. Ribonucleoprotein immune complexes, inducers of NETosis, require mitochondrial ROS for maximal NET stimulation. During this process, mitochondria become hypopolarized and translocate to the cell surface. Extracellular release of oxidized mitochondrial DNA is proinflammatory in vitro and, when injected into mice, stimulates type-I interferon (IFN) signaling through a pathway dependent on the DNA sensor, STING. Mitochondrial ROS is also necessary for spontaneous NETosis of low-density granulocytes from individuals with systemic lupus erythematosus (SLE). This was also observed in individuals with chronic granulomatous disease (CGD), which lack NADPH-oxidase activity, but still develop autoimmunity and type I-IFN signatures. Mitochondrial ROS inhibition in vivo reduces disease severity and type-I IFN responses in a mouse model of lupus. These findings highlight a role for mitochondria in the generation not only of NETs but also of pro-inflammatory oxidized mitochondrial DNA in autoimmune diseases. PMID:26779811

Near infrared spatial frequency domain fluorescence imaging of tumor phantoms containing erythrocyte-derived optical nanoplatforms

NASA Astrophysics Data System (ADS)

Burns, Joshua M.; Schaefer, Elise; Anvari, Bahman

2018-02-01

Light-activated theranostic constructs provide a multi-functional platform for optical imaging and phototherapeutic applications. Our group has engineered nano-sized vesicles derived from erythrocytes that encapsulate the FDAapproved near infrared (NIR) absorber indocyanine green (ICG). We refer to these constructs as NIR erythrocytemimicking transducers (NETs). Once photo-excited by NIR light these constructs can transduce the photons energy to emit fluorescence, generate heat, or induce chemical reactions. In this study, we investigated fluorescence imaging of NETs embedded within tumor phantoms using spatial frequency domain imaging (SFDI). Using SFDI, we were able to fluorescently image simulated tumors doped with different concentration of NETs. These preliminary results suggest that NETs can be used in conjunction with SFDI for potential tumor imaging applications.

Electric Power Quarterly, July-September 1985

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1986-01-29

The Electric Power Quarterly (EPQ) provides electric utilities' plant-level information about the cost, quantity, and quality of fossil fuel receipts, net generation, fuel consumption, and fuel stocks. The EPQ contains monthly data and quarterly totals for the reporting quarter. The data presented in this report were collected and published by the Energy Information Administration (EIA), to fulfill its responsibilities as specified in the Federal Energy Administration Act of 1974 (P.L. 93-275) as amended. This edition of the EPQ contains monthly data for the third quarter of 1985.

Optimization of Training Sets For Neural-Net Processing of Characteristic Patterns From Vibrating Solids

NASA Technical Reports Server (NTRS)

Decker, Arthur J. (Inventor)

2006-01-01

An artificial neural network is disclosed that processes holography generated characteristic pattern of vibrating structures along with finite-element models. The present invention provides for a folding operation for conditioning training sets for optimally training forward-neural networks to process characteristic fringe pattern. The folding pattern increases the sensitivity of the feed-forward network for detecting changes in the characteristic pattern The folding routine manipulates input pixels so as to be scaled according to the location in an intensity range rather than the position in the characteristic pattern.

CoryneRegNet: An ontology-based data warehouse of corynebacterial transcription factors and regulatory networks

PubMed Central

Baumbach, Jan; Brinkrolf, Karina; Czaja, Lisa F; Rahmann, Sven; Tauch, Andreas

2006-01-01

Background The application of DNA microarray technology in post-genomic analysis of bacterial genome sequences has allowed the generation of huge amounts of data related to regulatory networks. This data along with literature-derived knowledge on regulation of gene expression has opened the way for genome-wide reconstruction of transcriptional regulatory networks. These large-scale reconstructions can be converted into in silico models of bacterial cells that allow a systematic analysis of network behavior in response to changing environmental conditions. Description CoryneRegNet was designed to facilitate the genome-wide reconstruction of transcriptional regulatory networks of corynebacteria relevant in biotechnology and human medicine. During the import and integration process of data derived from experimental studies or literature knowledge CoryneRegNet generates links to genome annotations, to identified transcription factors and to the corresponding cis-regulatory elements. CoryneRegNet is based on a multi-layered, hierarchical and modular concept of transcriptional regulation and was implemented by using the relational database management system MySQL and an ontology-based data structure. Reconstructed regulatory networks can be visualized by using the yFiles JAVA graph library. As an application example of CoryneRegNet, we have reconstructed the global transcriptional regulation of a cellular module involved in SOS and stress response of corynebacteria. Conclusion CoryneRegNet is an ontology-based data warehouse that allows a pertinent data management of regulatory interactions along with the genome-scale reconstruction of transcriptional regulatory networks. These models can further be combined with metabolic networks to build integrated models of cellular function including both metabolism and its transcriptional regulation. PMID:16478536

Inferring Phylogenetic Networks Using PhyloNet.

PubMed

Wen, Dingqiao; Yu, Yun; Zhu, Jiafan; Nakhleh, Luay

2018-07-01

PhyloNet was released in 2008 as a software package for representing and analyzing phylogenetic networks. At the time of its release, the main functionalities in PhyloNet consisted of measures for comparing network topologies and a single heuristic for reconciling gene trees with a species tree. Since then, PhyloNet has grown significantly. The software package now includes a wide array of methods for inferring phylogenetic networks from data sets of unlinked loci while accounting for both reticulation (e.g., hybridization) and incomplete lineage sorting. In particular, PhyloNet now allows for maximum parsimony, maximum likelihood, and Bayesian inference of phylogenetic networks from gene tree estimates. Furthermore, Bayesian inference directly from sequence data (sequence alignments or biallelic markers) is implemented. Maximum parsimony is based on an extension of the "minimizing deep coalescences" criterion to phylogenetic networks, whereas maximum likelihood and Bayesian inference are based on the multispecies network coalescent. All methods allow for multiple individuals per species. As computing the likelihood of a phylogenetic network is computationally hard, PhyloNet allows for evaluation and inference of networks using a pseudolikelihood measure. PhyloNet summarizes the results of the various analyzes and generates phylogenetic networks in the extended Newick format that is readily viewable by existing visualization software.

An Investigation of Generalized Differential Evolution Metaheuristic for Multiobjective Optimal Crop-Mix Planning Decision

PubMed Central

Olugbara, Oludayo

2014-01-01

This paper presents an annual multiobjective crop-mix planning as a problem of concurrent maximization of net profit and maximization of crop production to determine an optimal cropping pattern. The optimal crop production in a particular planting season is a crucial decision making task from the perspectives of economic management and sustainable agriculture. A multiobjective optimal crop-mix problem is formulated and solved using the generalized differential evolution 3 (GDE3) metaheuristic to generate a globally optimal solution. The performance of the GDE3 metaheuristic is investigated by comparing its results with the results obtained using epsilon constrained and nondominated sorting genetic algorithms—being two representatives of state-of-the-art in evolutionary optimization. The performance metrics of additive epsilon, generational distance, inverted generational distance, and spacing are considered to establish the comparability. In addition, a graphical comparison with respect to the true Pareto front for the multiobjective optimal crop-mix planning problem is presented. Empirical results generally show GDE3 to be a viable alternative tool for solving a multiobjective optimal crop-mix planning problem. PMID:24883369

Mixing Enhancement in a Lobed Injector

NASA Technical Reports Server (NTRS)

Smith, L. L.; Majamaki, A. J.; Lam, I. T.; Delabroy, O.; Karagozian, A. R.; Marble, F. E.; Smith, O. I.

1997-01-01

An experimental investigation of the non-reactive mixing processes associated with a lobed fuel injector in a coflowing air stream is presented. The lobed fuel injector is a device which generates streamwise vorticity, producing high strain rates which can enhance the mixing of reactants while delaying ignition in a controlled manner. The lobed injectors examined in the present study consist of two corrugated plates between which a fuel surrogate, CO2, is injected into coflowing air. Acetone is seeded in the CO2 supply as a fuel marker. Comparison of two alternative lobed injector geometries is made with a straight fuel injector to determine net differences in mixing and strain fields due to streamwise vorticity generation. Planar laser-induced fluorescence (PLIF) of the seeded acetone yields two-dimensional images of the scalar concentration field at various downstream locations, from which local mixing and scalar dissipation rates are computed. It is found that the lobed injector geometry can enhance molecular mixing and create a highly strained flowfield, and that the strain rates generated by scalar energy dissipation can potentially delay ignition in a reacting flowfield.

An investigation of generalized differential evolution metaheuristic for multiobjective optimal crop-mix planning decision.

PubMed

Adekanmbi, Oluwole; Olugbara, Oludayo; Adeyemo, Josiah

2014-01-01

This paper presents an annual multiobjective crop-mix planning as a problem of concurrent maximization of net profit and maximization of crop production to determine an optimal cropping pattern. The optimal crop production in a particular planting season is a crucial decision making task from the perspectives of economic management and sustainable agriculture. A multiobjective optimal crop-mix problem is formulated and solved using the generalized differential evolution 3 (GDE3) metaheuristic to generate a globally optimal solution. The performance of the GDE3 metaheuristic is investigated by comparing its results with the results obtained using epsilon constrained and nondominated sorting genetic algorithms-being two representatives of state-of-the-art in evolutionary optimization. The performance metrics of additive epsilon, generational distance, inverted generational distance, and spacing are considered to establish the comparability. In addition, a graphical comparison with respect to the true Pareto front for the multiobjective optimal crop-mix planning problem is presented. Empirical results generally show GDE3 to be a viable alternative tool for solving a multiobjective optimal crop-mix planning problem.

MS Data Miner: a web-based software tool to analyze, compare, and share mass spectrometry protein identifications.

PubMed

Dyrlund, Thomas F; Poulsen, Ebbe T; Scavenius, Carsten; Sanggaard, Kristian W; Enghild, Jan J

2012-09-01

Data processing and analysis of proteomics data are challenging and time consuming. In this paper, we present MS Data Miner (MDM) (http://sourceforge.net/p/msdataminer), a freely available web-based software solution aimed at minimizing the time required for the analysis, validation, data comparison, and presentation of data files generated in MS software, including Mascot (Matrix Science), Mascot Distiller (Matrix Science), and ProteinPilot (AB Sciex). The program was developed to significantly decrease the time required to process large proteomic data sets for publication. This open sourced system includes a spectra validation system and an automatic screenshot generation tool for Mascot-assigned spectra. In addition, a Gene Ontology term analysis function and a tool for generating comparative Excel data reports are included. We illustrate the benefits of MDM during a proteomics study comprised of more than 200 LC-MS/MS analyses recorded on an AB Sciex TripleTOF 5600, identifying more than 3000 unique proteins and 3.5 million peptides. © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Economic analysis of the global polio eradication initiative.

PubMed

Duintjer Tebbens, Radboud J; Pallansch, Mark A; Cochi, Stephen L; Wassilak, Steven G F; Linkins, Jennifer; Sutter, Roland W; Aylward, R Bruce; Thompson, Kimberly M

2010-12-16

The global polio eradication initiative (GPEI), which started in 1988, represents the single largest, internationally coordinated public health project to date. Completion remains within reach, with type 2 wild polioviruses apparently eradicated since 1999 and fewer than 2000 annual paralytic poliomyelitis cases of wild types 1 and 3 reported since then. This economic analysis of the GPEI reflects the status of the program as of February 2010, including full consideration of post-eradication policies. For the GPEI intervention, we consider the actual pre-eradication experience to date followed by two distinct potential future post-eradication vaccination policies. We estimate GPEI costs based on actual and projected expenditures and poliomyelitis incidence using reported numbers corrected for underreporting and model projections. For the comparator, which assumes only routine vaccination for polio historically and into the future (i.e., no GPEI), we estimate poliomyelitis incidence using a dynamic infection transmission model and costs based on numbers of vaccinated children. Cost-effectiveness ratios for the GPEI vs. only routine vaccination qualify as highly cost-effective based on standard criteria. We estimate incremental net benefits of the GPEI between 1988 and 2035 of approximately 40-50 billion dollars (2008 US dollars; 1988 net present values). Despite the high costs of achieving eradication in low-income countries, low-income countries account for approximately 85% of the total net benefits generated by the GPEI in the base case analysis. The total economic costs saved per prevented paralytic poliomyelitis case drive the incremental net benefits, which become positive even if we estimate the loss in productivity as a result of disability as below the recommended value of one year in average per-capita gross national income per disability-adjusted life year saved. Sensitivity analysis suggests that the finding of positive net benefits of the GPEI remains robust over a wide range of assumptions, and that consideration of the additional net benefits of externalities that occurred during polio campaigns to date, such as the mortality reduction associated with delivery of Vitamin A supplements, significantly increases the net benefits. This study finds a strong economic justification for the GPEI despite the rising costs of the initiative. Copyright © 2010 Elsevier Ltd. All rights reserved.

Ontogeny of flow-stimulated potassium secretion in rabbit cortical collecting duct: functional and molecular aspects.

PubMed

Woda, Craig B; Miyawaki, Nobuyuki; Ramalakshmi, Santhanam; Ramkumar, Mohan; Rojas, Raul; Zavilowitz, Beth; Kleyman, Thomas R; Satlin, Lisa M

2003-10-01

High urinary flow rates stimulate K secretion in the fully differentiated but not neonatal or weanling rabbit cortical collecting duct (CCD). Both small-conductance secretory K and high-conductance Ca2+/stretch-activated maxi-K channels have been identified in the apical membrane of the mature CCD by patch-clamp analysis. We reported that flow-stimulated net K secretion in the adult rabbit CCD is 1) blocked by TEA and charybdotoxin, inhibitors of intermediate- and high-conductance (maxi-K) Ca2+-activated K channels, and 2) associated with increases in net Na absorption and intracellular Ca2+ concentration ([Ca2+]i). The present study examined whether the absence of flow-stimulated K secretion early in life is due to a 1) limited flow-induced rise in net Na absorption and/or [Ca2+]i and/or 2) paucity of apical maxi-K channels. An approximately sixfold increase in tubular fluid flow rate in CCDs isolated from 4-wk-old rabbits and microperfused in vitro led to an increase in net Na absorption and [Ca2+]i, similar in magnitude to the response observed in 6-wk-old tubules, but it failed to generate an increase in net K secretion. By 5 wk of age, there was a small, but significant, flow-stimulated rise in net K secretion that increased further by 6 wk of life. Luminal perfusion with iberiotoxin blocked the flow stimulation of net K secretion in the adult CCD, confirming the identity of the maxi-K channel in this response. Maxi-K channel alpha-subunit message was consistently detected in single CCDs from animals >/=4 wk of age by RT-PCR. Indirect immunofluorescence microscopy using antibodies directed against the alpha-subunit revealed apical labeling of intercalated cells in cryosections from animals >/=5 wk of age; principal cell labeling was generally intracellular and punctate. We speculate that the postnatal appearance of flow-dependent K secretion is determined by the transcriptional/translational regulation of expression of maxi-K channels. Furthermore, our studies suggest a novel function for intercalated cells in mediating flow-stimulated K secretion.

A Petri net controller for distributed hierarchical systems. Thesis

NASA Technical Reports Server (NTRS)

Peck, Joseph E.

1991-01-01

The solutions to a wide variety of problems are often best organized as a distributed hierarchical system. These systems can be graphically and mathematically modeled through the use of Petri nets, which can easily represent synchronous, asynchronous, and concurrent operations. This thesis presents a controller implementation based on Petri nets and a design methodology for the interconnection of distributed Petri nets. Two case studies are presented in which the controller operates a physical system, the Center for Intelligent Robotic Systems for Space Exploration Dual Arm Robotic Testbed.

Bi-directional transition nets

NASA Astrophysics Data System (ADS)

Staines, Anthony Spiteri

2017-06-01

Ordinary Petri nets are forward directed transition systems. Modern transition systems events and event flows are reversible. Hence modeling structures that reflect this are important. The creation of a bi-directional Petri net extends the modeling power of Petri nets. This work presents the successful implementation of a bi-directional transition net. Some toy examples in comparison to Petri nets are given showing the increased modeling power in a compacted form. The results show some interesting findings on how the expressive power of these structures has been increased.

BioNetFit: a fitting tool compatible with BioNetGen, NFsim and distributed computing environments

DOE PAGES

Thomas, Brandon R.; Chylek, Lily A.; Colvin, Joshua; ...

2015-11-09

Rule-based models are analyzed with specialized simulators, such as those provided by the BioNetGen and NFsim open-source software packages. Here in this paper, we present BioNetFit, a general-purpose fitting tool that is compatible with BioNetGen and NFsim. BioNetFit is designed to take advantage of distributed computing resources. This feature facilitates fitting (i.e. optimization of parameter values for consistency with data) when simulations are computationally expensive.

HeatmapGenerator: high performance RNAseq and microarray visualization software suite to examine differential gene expression levels using an R and C++ hybrid computational pipeline.

PubMed

Khomtchouk, Bohdan B; Van Booven, Derek J; Wahlestedt, Claes

2014-01-01

The graphical visualization of gene expression data using heatmaps has become an integral component of modern-day medical research. Heatmaps are used extensively to plot quantitative differences in gene expression levels, such as those measured with RNAseq and microarray experiments, to provide qualitative large-scale views of the transcriptonomic landscape. Creating high-quality heatmaps is a computationally intensive task, often requiring considerable programming experience, particularly for customizing features to a specific dataset at hand. Software to create publication-quality heatmaps is developed with the R programming language, C++ programming language, and OpenGL application programming interface (API) to create industry-grade high performance graphics. We create a graphical user interface (GUI) software package called HeatmapGenerator for Windows OS and Mac OS X as an intuitive, user-friendly alternative to researchers with minimal prior coding experience to allow them to create publication-quality heatmaps using R graphics without sacrificing their desired level of customization. The simplicity of HeatmapGenerator is that it only requires the user to upload a preformatted input file and download the publicly available R software language, among a few other operating system-specific requirements. Advanced features such as color, text labels, scaling, legend construction, and even database storage can be easily customized with no prior programming knowledge. We provide an intuitive and user-friendly software package, HeatmapGenerator, to create high-quality, customizable heatmaps generated using the high-resolution color graphics capabilities of R. The software is available for Microsoft Windows and Apple Mac OS X. HeatmapGenerator is released under the GNU General Public License and publicly available at: http://sourceforge.net/projects/heatmapgenerator/. The Mac OS X direct download is available at: http://sourceforge.net/projects/heatmapgenerator/files/HeatmapGenerator_MAC_OSX.tar.gz/download. The Windows OS direct download is available at: http://sourceforge.net/projects/heatmapgenerator/files/HeatmapGenerator_WINDOWS.zip/download.

Net vapor generation point in boiling flow of trichlorotrifluoroethane at high pressures

NASA Technical Reports Server (NTRS)

Dougall, R. S.; Lippert, T. E.

1973-01-01

The conditions at which the void in subcooled boiling starts to undergo a rapid increase were studied experimentally. The experiments were performed in a 12.7 x 9.5 mm rectangular channel. Heating was from a 3.2 mm wide strip embedded in one wall. The pressure ranged from 9.45 to 20.7 bar, mass velocity from 600 to 7000 kg/sq m sec, and subcooling from 16 to 67 C. Photographs were used to determine when detached bubbles first appeared in the bulk flow. Measurements of bubble layer thickness along the wall were also made. Results showed that the point of net vapor generation is close to the occurrence of fully-developed boiling.

Neutrophil Extracellular Traps Identification in Tegumentary Lesions of Patients with Paracoccidioidomycosis and Different Patterns of NETs Generation In Vitro

PubMed Central

Della Coletta, Amanda Manoel; Bachiega, Tatiana Fernanda; de Quaglia e Silva, Juliana Carvalho; Soares, Ângela Maria Victoriano de Campos; De Faveri, Julio; Marques, Silvio Alencar; Marques, Mariângela Esther Alencar; Ximenes, Valdecir Farias; Dias-Melicio, Luciane Alarcão

2015-01-01

Paracoccidioidomycosis (PCM) is a systemic mycosis, endemic in most Latin American countries, especially in Brazil. It is caused by the thermo-dimorphic fungus of the genus Paracoccidioides (Paracoccidioides brasiliensis and Paracoccidioides lutzii). Innate immune response plays a crucial role in host defense against fungal infections, and neutrophils (PMNs) are able to combat microorganisms with three different mechanisms: phagocytosis, secretion of granular proteins, which have antimicrobial properties, and the most recent described mechanism called NETosis. This new process is characterized by the release of net-like structures called Neutrophil Extracellular Traps (NETs), which is composed of nuclear (decondensed DNA and histones) and granular material such as elastase. Several microorganisms have the ability of inducing NETs formation, including gram-positive and gram-negative bacteria, viruses and some fungi. We proposed to identify NETs in tegumentary lesions of patients with PCM and to analyze the interaction between two strains of P. brasiliensis and human PMNs by NETs formation in vitro. In this context, the presence of NETs in vivo was evidenced in tegumentary lesions of patients with PCM by confocal spectrum analyzer. Furthermore, we showed that the high virulent P. brasiliensis strain 18 (Pb18) and the lower virulent strain Pb265 are able to induce different patterns of NETs formation in vitro. The quantification of extracellular DNA corroborates the idea of the ability of P. brasiliensis in inducing NETs release. In conclusion, our data show for the first time the identification of NETs in lesions of patients with PCM and demonstrate distinct patterns of NETs in cultures challenged with fungi in vitro. The presence of NETs components both in vivo and in vitro open new possibilities for the detailed investigation of immunity in PCM. PMID:26327485

Distributed state-space generation of discrete-state stochastic models

NASA Technical Reports Server (NTRS)

Ciardo, Gianfranco; Gluckman, Joshua; Nicol, David

1995-01-01

High-level formalisms such as stochastic Petri nets can be used to model complex systems. Analysis of logical and numerical properties of these models of ten requires the generation and storage of the entire underlying state space. This imposes practical limitations on the types of systems which can be modeled. Because of the vast amount of memory consumed, we investigate distributed algorithms for the generation of state space graphs. The distributed construction allows us to take advantage of the combined memory readily available on a network of workstations. The key technical problem is to find effective methods for on-the-fly partitioning, so that the state space is evenly distributed among processors. In this paper we report on the implementation of a distributed state-space generator that may be linked to a number of existing system modeling tools. We discuss partitioning strategies in the context of Petri net models, and report on performance observed on a network of workstations, as well as on a distributed memory multi-computer.

A mixture neural net for multispectral imaging spectrometer processing

NASA Technical Reports Server (NTRS)

Casasent, David; Slagle, Timothy

1990-01-01

Each spatial region viewed by an imaging spectrometer contains various elements in a mixture. The elements present and the amount of each are to be determined. A neural net solution is considered. Initial optical neural net hardware is described. The first simulations on the component requirements of a neural net are considered. The pseudoinverse solution is shown to not suffice, i.e. a neural net solution is required.

Carbon dioxide addition to coral reef waters suppresses net community calcification.

PubMed

Albright, Rebecca; Takeshita, Yuichiro; Koweek, David A; Ninokawa, Aaron; Wolfe, Kennedy; Rivlin, Tanya; Nebuchina, Yana; Young, Jordan; Caldeira, Ken

2018-03-22

Coral reefs feed millions of people worldwide, provide coastal protection and generate billions of dollars annually in tourism revenue. The underlying architecture of a reef is a biogenic carbonate structure that accretes over many years of active biomineralization by calcifying organisms, including corals and algae. Ocean acidification poses a chronic threat to coral reefs by reducing the saturation state of the aragonite mineral of which coral skeletons are primarily composed, and lowering the concentration of carbonate ions required to maintain the carbonate reef. Reduced calcification, coupled with increased bioerosion and dissolution, may drive reefs into a state of net loss this century. Our ability to predict changes in ecosystem function and associated services ultimately hinges on our understanding of community- and ecosystem-scale responses. Past research has primarily focused on the responses of individual species rather than evaluating more complex, community-level responses. Here we use an in situ carbon dioxide enrichment experiment to quantify the net calcification response of a coral reef flat to acidification. We present an estimate of community-scale calcification sensitivity to ocean acidification that is, to our knowledge, the first to be based on a controlled experiment in the natural environment. This estimate provides evidence that near-future reductions in the aragonite saturation state will compromise the ecosystem function of coral reefs.

Network-assisted investigation of virulence and antibiotic-resistance systems in Pseudomonas aeruginosa

NASA Astrophysics Data System (ADS)

Hwang, Sohyun; Kim, Chan Yeong; Ji, Sun-Gou; Go, Junhyeok; Kim, Hanhae; Yang, Sunmo; Kim, Hye Jin; Cho, Ara; Yoon, Sang Sun; Lee, Insuk

2016-05-01

Pseudomonas aeruginosa is a Gram-negative bacterium of clinical significance. Although the genome of PAO1, a prototype strain of P. aeruginosa, has been extensively studied, approximately one-third of the functional genome remains unknown. With the emergence of antibiotic-resistant strains of P. aeruginosa, there is an urgent need to develop novel antibiotic and anti-virulence strategies, which may be facilitated by an approach that explores P. aeruginosa gene function in systems-level models. Here, we present a genome-wide functional network of P. aeruginosa genes, PseudomonasNet, which covers 98% of the coding genome, and a companion web server to generate functional hypotheses using various network-search algorithms. We demonstrate that PseudomonasNet-assisted predictions can effectively identify novel genes involved in virulence and antibiotic resistance. Moreover, an antibiotic-resistance network based on PseudomonasNet reveals that P. aeruginosa has common modular genetic organisations that confer increased or decreased resistance to diverse antibiotics, which accounts for the pervasiveness of cross-resistance across multiple drugs. The same network also suggests that P. aeruginosa has developed mechanism of trade-off in resistance across drugs by altering genetic interactions. Taken together, these results clearly demonstrate the usefulness of a genome-scale functional network to investigate pathogenic systems in P. aeruginosa.

Carbon dioxide addition to coral reef waters suppresses net community calcification

NASA Astrophysics Data System (ADS)

Albright, Rebecca; Takeshita, Yuichiro; Koweek, David A.; Ninokawa, Aaron; Wolfe, Kennedy; Rivlin, Tanya; Nebuchina, Yana; Young, Jordan; Caldeira, Ken

2018-03-01

Coral reefs feed millions of people worldwide, provide coastal protection and generate billions of dollars annually in tourism revenue. The underlying architecture of a reef is a biogenic carbonate structure that accretes over many years of active biomineralization by calcifying organisms, including corals and algae. Ocean acidification poses a chronic threat to coral reefs by reducing the saturation state of the aragonite mineral of which coral skeletons are primarily composed, and lowering the concentration of carbonate ions required to maintain the carbonate reef. Reduced calcification, coupled with increased bioerosion and dissolution, may drive reefs into a state of net loss this century. Our ability to predict changes in ecosystem function and associated services ultimately hinges on our understanding of community- and ecosystem-scale responses. Past research has primarily focused on the responses of individual species rather than evaluating more complex, community-level responses. Here we use an in situ carbon dioxide enrichment experiment to quantify the net calcification response of a coral reef flat to acidification. We present an estimate of community-scale calcification sensitivity to ocean acidification that is, to our knowledge, the first to be based on a controlled experiment in the natural environment. This estimate provides evidence that near-future reductions in the aragonite saturation state will compromise the ecosystem function of coral reefs.

Health resources and Internet with reference to HealthNet Nepal.

PubMed

Pradhan, Mohan Raj

2003-01-01

Technologies with the ability to send information in a fast, efficient and cheap fashion, such as the Internet--can provide dramatic improvements in access to information, advice and care. This article discusses importance of Internet, applications of Internet in providing information services in the health field. The Internet was developed in western countries and the information flow is from North to South. But for decision making within a country, information generated within a country is needed. For this, an organization like HealthNet Nepal is developed. The article discusses the various services of HealthNet Nepal and discusses about its unique features as compared to commercial ISPs.

Marine species mortality in derelict fishing nets in Puget Sound, WA and the cost/benefits of derelict net removal.

PubMed

Gilardi, Kirsten V K; Carlson-Bremer, Daphne; June, Jeffrey A; Antonelis, Kyle; Broadhurst, Ginny; Cowan, Tom

2010-03-01

Derelict fishing gear persists for decades and impacts marine species and underwater habitats. Agencies and organizations are removing significant amounts of derelict gear from marine waters in the United States. Using data collected from repeated survey dives on derelict gillnets in Puget Sound, Washington, we estimated the daily catch rate of a given derelict gillnet, and developed a model to predict expected total mortality caused by a given net based on entanglement data collected upon its removal. We also generated a cost:benefit ratio for derelict gear removal utilizing known true costs compared to known market values of the resources benefiting from derelict gear removal. For one study net, we calculated 4368 crab entangled during the impact lifetime of the net, at a loss of 19,656 dollars of Dungeness crab to the commercial fishery, compared to 1358 dollars in costs to remove a given gillnet, yielding a cost:benefit ratio of 1:14.5. Copyright 2009 Elsevier Ltd. All rights reserved.

Direct and indirect costs and potential cost savings of laparoscopic adjustable gastric banding among obese patients with diabetes.

PubMed

Finkelstein, Eric A; Allaire, Benjamin T; DiBonaventura, Marco DaCosta; Burgess, Somali M

2011-09-01

To estimate the time to breakeven and 5-year net costs for laparoscopic adjustable gastric banding among obese patients with diabetes taking direct and indirect costs into account. Indirect cost savings were generated by quantifying the cross-sectional relationship between medical expenditures and absenteeism and between medical expenditures and presenteeism (reduced on-the-job productivity) and simulating indirect cost savings based on these multipliers and reductions in direct medical costs available in the literature. Time to breakeven was estimated to be nine quarters with and without the inclusion of indirect costs. After 5 years, net savings increase from $26570 (±$9000) to $34160 (±$10 380) when indirect costs are included. This study presented a novel approach for incorporating indirect costs into cost-benefit analyses. Application to gastric banding revealed that inclusion of indirect costs improves the financial outlook for the procedure. (C)2011The American College of Occupational and Environmental Medicine

Incorporating seismic phase correlations into a probabilistic model of global-scale seismology

NASA Astrophysics Data System (ADS)

Arora, Nimar

2013-04-01

We present a probabilistic model of seismic phases whereby the attributes of the body-wave phases are correlated to those of the first arriving P phase. This model has been incorporated into NET-VISA (Network processing Vertically Integrated Seismic Analysis) a probabilistic generative model of seismic events, their transmission, and detection on a global seismic network. In the earlier version of NET-VISA, seismic phase were assumed to be independent of each other. Although this didn't affect the quality of the inferred seismic bulletin, for the most part, it did result in a few instances of anomalous phase association. For example, an S phase with a smaller slowness than the corresponding P phase. We demonstrate that the phase attributes are indeed highly correlated, for example the uncertainty in the S phase travel time is significantly reduced given the P phase travel time. Our new model exploits these correlations to produce better calibrated probabilities for the events, as well as fewer anomalous associations.

CMEMS (Copernicus Marine Environment Monitoring Service) In Situ Thematic Assembly Centre: A service for operational Oceanography

NASA Astrophysics Data System (ADS)

Manzano Muñoz, Fernando; Pouliquen, Sylvie; Petit de la Villeon, Loic; Carval, Thierry; Loubrieu, Thomas; Wedhe, Henning; Sjur Ringheim, Lid; Hammarklint, Thomas; Tamm, Susanne; De Alfonso, Marta; Perivoliotis, Leonidas; Chalkiopoulos, Antonis; Marinova, Veselka; Tintore, Joaquin; Troupin, Charles

2016-04-01

Copernicus, previously known as GMES (Global Monitoring for Environment and Security), is the European Programme for the establishment of a European capacity for Earth Observation and Monitoring. Copernicus aims to provide a sustainable service for Ocean Monitoring and Forecasting validated and commissioned by users. From May 2015, the Copernicus Marine Environment Monitoring Service (CMEMS) is working on an operational mode through a contract with services engagement (result is regular data provision). Within CMEMS, the In Situ Thematic Assembly Centre (INSTAC) distributed service integrates in situ data from different sources for operational oceanography needs. CMEMS INSTAC is collecting and carrying out quality control in a homogeneous manner on data from providers outside Copernicus (national and international networks), to fit the needs of internal and external users. CMEMS INSTAC has been organized in 7 regional Dissemination Units (DUs) to rely on the EuroGOOS ROOSes. Each DU aggregates data and metadata provided by a series of Production Units (PUs) acting as an interface for providers. Homogeneity and standardization are key features to ensure coherent and efficient service. All DUs provide data in the OceanSITES NetCDF format 1.2 (based on NetCDF 3.6), which is CF compliant, relies on SeaDataNet vocabularies and is able to handle profile and time-series measurements. All the products, both near real-time (NRT) and multi-year (REP), are available online for every CMEMS registered user through an FTP service. On top of the FTP service, INSTAC products are available through Oceanotron, an open-source data server dedicated to marine observations dissemination. It provides services such as aggregation on spatio-temporal coordinates and observed parameters, and subsetting on observed parameters and metadata. The accuracy of the data is checked on various levels. Quality control procedures are applied for the validity of the data and correctness tests for the metadata of each NetCDF file. The quality control procedures for the data include different routines for NRT and REP products. Key Performance Indicators (KPI) for monitoring purposes are also used in Copernicus. They allow a periodic monitoring of the availability, quantity and quality of the INSTAC data integrated in the NRT products. Statistical reports are generated on quarterly and yearly basis to provide more visibility on the coverage in space and time of the INSTAC NRT and REP products, as well as information on their quality. These reports are generated using Java and Python procedures developed within the INSTAC group. One of the most critical tasks for the DUs is to generate NetCDF files compliant with the agreed format. Many tools and programming libraries have been developed for that purpose, for instance Unidata Java Library. These tools provide NetCDF data management capabilities including creation, reading and modification. Some DUs have also developed regional data portals which offer useful information for the users including data charts, platforms availability through interactive maps, KPI and statistical figures and direct access to the FTP service. The proposed presentation will detail Copernicus in situ data service and the monitoring tools that have been developed by the INSTAC group.

The Myth about Students

ERIC Educational Resources Information Center

Oblinger, Diana G.; Hawkins, Brian L.

2005-01-01

In this article, the authors discuss the reality of today's current students and their expectations of the institutions they attend. Specifically, they describe the current generation, the Net Generation, of traditional-age college students who have grown up with computers and the Internet, living in a rapid-response, multimedia, anytime-anywhere…

Indirectly Estimating International Net Migration Flows by Age and Gender: The Community Demographic Model International Migration (CDM-IM) Dataset

PubMed Central

Nawrotzki, Raphael J.; Jiang, Leiwen

2015-01-01

Although data for the total number of international migrant flows is now available, no global dataset concerning demographic characteristics, such as the age and gender composition of migrant flows exists. This paper reports on the methods used to generate the CDM-IM dataset of age and gender specific profiles of bilateral net (not gross) migrant flows. We employ raw data from the United Nations Global Migration Database and estimate net migrant flows by age and gender between two time points around the year 2000, accounting for various demographic processes (fertility, mortality). The dataset contains information on 3,713 net migrant flows. Validation analyses against existing data sets and the historical, geopolitical context demonstrate that the CDM-IM dataset is of reasonably high quality. PMID:26692590

A Probabilistic Model of Global-Scale Seismology with Veith-Clawson Amplitude Corrections

NASA Astrophysics Data System (ADS)

Arora, N. S.; Russell, S.

2013-12-01

We present a probabilistic generative model of global-scale seismology, NET-VISA, that is designed to address the event detection and location problem of seismic monitoring. The model is based on a standard Bayesian framework with prior probabilities for event generation and propagation as well as likelihoods of detection and arrival (or onset) parameters. The model is supplemented with a greedy search algorithm that iteratively improves the predicted bulletin with respect to the posterior probability. Our prior model incorporates both seismic theory and empirical observations as appropriate. For instance, we use empirical observations for the expected rates of earthquake at each point on the earth, while we use the Gutenberg-Richter law for the the expected magnitude distribution of these earthquakes. In this work, we describe an extension of our model where we include the Veith-Clawson (1972) amplitude decline curves in our empirically calibrated arrival amplitude model. While this change doesn't alter the overall event-detection results, we have chosen to keep the Veith-Clawson curves since they are more seismically accurate. We also describe a recent change to our search algorithm, whereby we now consider multiple hypotheses when we encounter a series of closely spaced arrivals which could be explained by either a single event or multiple co-located events. This change has led to a sharp improvement in our results on large after-shock sequences. We use the analyst-curated LEB bulletin or the REB bulletin, which is the published product of the IDC, as a reference and measure the overlap (percentage of reference events that are matched) and inconsistency (percentage of test bulletin events that don't match anything in the reference) of a one-to-one matching between the test and the reference bulletins. In the table below we show results for NET-VISA and SEL3, which is produced by the existing GA software, for the whole of 2009. These results show that NET-VISA, which is restricted to use arrivals with a 6 hour lag (in order to be comparable to SEL3), reduces the number of missed events by a factor of 2.5 while simultaneously reducing the rate of spurious events. Further, these "spurious" NET-VISA events, in fact, include many real events which are missed by the human analysts. When we compare the NET-VISA events, with arrivals from at least 3 stations (to be comparable to LEB), with NEIC events (in the ISC catalog) over the continental United States, as well as NNC events over Central Asia, we find that NET-VISA identifies 1.5 to 2 times the number of events that the IDC analysts find. Most of these additional events are in the 2--4 mb or ML range. Our experiments also confirm that NET-VISA accurately located each of the recent nuclear explosions to within 5 km of the LEB location. For large after-shock sequences, NET-VISA has been shown to be very efficient as well as accurate. For example on the Tohoku sequence (March 10 -- 14, 2011), NET-VISA (running time 2.57 days) had an overlap of 82.7 % with LEB and inconsistency of 26.8 % versus SEL3's overlap of 71.9 % and inconsistency of 40 %.

Differential ubiquitination in NETs regulates macrophage responses in systemic lupus erythematosus.

PubMed

Barrera-Vargas, Ana; Gómez-Martín, Diana; Carmona-Rivera, Carmelo; Merayo-Chalico, Javier; Torres-Ruiz, Jiram; Manna, Zerai; Hasni, Sarfaraz; Alcocer-Varela, Jorge; Kaplan, Mariana J

2018-06-01

To assess if ubiquitinated proteins potentially present in neutrophil extracellular traps (NETs) can modify cellular responses and induce inflammatory mechanisms in patients with systemic lupus erythematosus (SLE) and healthy subjects. We studied 74 subjects with SLE and 77 healthy controls. Neutrophils and low-density granulocytes were isolated, and NETs were induced. Ubiquitin content was quantified in NETs by western blot analysis, ELISA and immunofluorescence microscopy, while ubiquitination of NET proteins was assessed by immunoprecipitation. Monocyte-derived macrophages from SLE and controls were isolated and stimulated with NETs or ubiquitin. Calcium flux and cytokine synthesis were measured following these stimuli. NETs contain ubiquitinated proteins, with a lower expression of polyubiquitinated proteins in subjects with SLE than in controls. Myeloperoxidase (MPO) is present in ubiquitinated form in NETs. Patients with SLE develop antiubiquitinated MPO antibodies, and titres positively correlate with Systemic Lupus Erythematosus Disease Activity Index (SLEDAI) score (P<0.01), and negatively correlate with complement components (P<0.01). Stimulation of monocyte-derived macrophages with NETs or with ubiquitin led to enhanced calcium flux. In addition, stimulation with NETs led to enhanced cytokine (tumour necrosis factor-α and interleukin-10) production in macrophages from patients with SLE when compared with controls, which was hampered by inhibition of NET internalisation by macrophages. This is the first study to find ubiquitinated proteins in NETs, and evidence for adaptive immune responses directed towards ubiquitinated NET proteins in SLE. The distinct differences in ubiquitin species profile in NETs compared with healthy controls may contribute to dampened anti-inflammatory responses observed in SLE. These results also support a role for extracellular ubiquitin in inflammation in SLE. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

The equivalency between logic Petri workflow nets and workflow nets.

PubMed

Wang, Jing; Yu, ShuXia; Du, YuYue

2015-01-01

Logic Petri nets (LPNs) can describe and analyze batch processing functions and passing value indeterminacy in cooperative systems. Logic Petri workflow nets (LPWNs) are proposed based on LPNs in this paper. Process mining is regarded as an important bridge between modeling and analysis of data mining and business process. Workflow nets (WF-nets) are the extension to Petri nets (PNs), and have successfully been used to process mining. Some shortcomings cannot be avoided in process mining, such as duplicate tasks, invisible tasks, and the noise of logs. The online shop in electronic commerce in this paper is modeled to prove the equivalence between LPWNs and WF-nets, and advantages of LPWNs are presented.

The Equivalency between Logic Petri Workflow Nets and Workflow Nets

PubMed Central

Wang, Jing; Yu, ShuXia; Du, YuYue

2015-01-01

Logic Petri nets (LPNs) can describe and analyze batch processing functions and passing value indeterminacy in cooperative systems. Logic Petri workflow nets (LPWNs) are proposed based on LPNs in this paper. Process mining is regarded as an important bridge between modeling and analysis of data mining and business process. Workflow nets (WF-nets) are the extension to Petri nets (PNs), and have successfully been used to process mining. Some shortcomings cannot be avoided in process mining, such as duplicate tasks, invisible tasks, and the noise of logs. The online shop in electronic commerce in this paper is modeled to prove the equivalence between LPWNs and WF-nets, and advantages of LPWNs are presented. PMID:25821845

CARGO: effective format-free compressed storage of genomic information

PubMed Central

Roguski, Łukasz; Ribeca, Paolo

2016-01-01

The recent super-exponential growth in the amount of sequencing data generated worldwide has put techniques for compressed storage into the focus. Most available solutions, however, are strictly tied to specific bioinformatics formats, sometimes inheriting from them suboptimal design choices; this hinders flexible and effective data sharing. Here, we present CARGO (Compressed ARchiving for GenOmics), a high-level framework to automatically generate software systems optimized for the compressed storage of arbitrary types of large genomic data collections. Straightforward applications of our approach to FASTQ and SAM archives require a few lines of code, produce solutions that match and sometimes outperform specialized format-tailored compressors and scale well to multi-TB datasets. All CARGO software components can be freely downloaded for academic and non-commercial use from http://bio-cargo.sourceforge.net. PMID:27131376

A study on economic power dispatch grid connected PV power plant in educational institutes

NASA Astrophysics Data System (ADS)

Singh, Kuldip; Kumar, M. Narendra; Mishra, Satyasis

2018-04-01

India has main concerns on environment and escalation of fuel prices with respect to diminution of fossil fuel reserves and the major focus on renewable Energy sources for power generation to fulfill the present and future energy demand. Installation of PV power plants in the Educational Institutions has grown up drastically throughout India. More PV power plant are integrated with load and grid through net metering. Therefore, this paper is an analysis of the 75kWp PV plant at chosen buses, considering the need of minimum demand from the grid. The case study is carried out for different generation level throughout the day and year w.r.t load and climate changes, load sharing on grid. The economic dispatch model developed for PV plant integrated with Grid.

Defending the Doomed: Implicit Strategies Concerning Protection of First-Person Shooter Games

PubMed Central

Munko, Daniel; Glock, Sabine; Bente, Gary

2012-01-01

Abstract Censorship of violent digital games, especially first-person shooter (FPS) games, is broadly discussed between generations. While older people are concerned about possible negative influences of these games, not only players but also nonplayers of the younger net-generation seem to deny any association with real aggressive behavior. Our study aimed at investigating defense mechanisms players and nonplayers use to defend FPS and peers with playing habits. By using a lexical decision task, we found that aggressive concepts are activated by priming the content of FPS but suppressed afterward. Only if participants were instructed to actively suppress aggressive concepts after priming, thought suppression was no longer necessary. Young people still do have negative associations with violent video games. These associations are neglected by implicitly applying defense strategies—independent of own playing habits—to protect this specific hobby, which is common for the net-generation. PMID:22515170

Electric power monthly, June 1988

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1988-09-15

Total net generation by electric utilities in the United States for the month of June 1988 was 232,183 gigawatthours, 3 percent higher than the amount reported a year ago. Although temperatures (measured by cooling degree days) for June 1988 were 9 percent warmer than normal, they were 3 percent cooler than for June 1987. A large portion of that higher demand for electricity was met by nuclear-powered generation. Net generation from nuclear power during June 1988 (44,079 gigawatthours) was only 1 percent below the record set in January of this year, and 21 percent above that reported in June 1987more » (36,560 gigawatthours). The only energy source other than nuclear that reported higher levels of net generation during June 1988 was coal, up 2 percent over the same period last year. Warmer-than-normal temperatures did, however, have an affect on various parts of the country. For example, on Wednesday, June 22, 1988, unseasonably high temperatures forced the Pennsylvania, New Jersey, and Maryland Interconnection (PJM) into a system-wide 5-percent voltage reduction for 2 hours. Contributing to that reduction in voltage was the shutdown of the Three Mile Island, Unit 1, for refueling and the closing of the Peach Bottom Units 2 and 3 by the Nuclear Regulatory Commission. Three Mile Island, Unit 1, normally provides the PJM system with about 800 megawatts while the two Peach Bottom units, combined, provide approximately 2100 megawatts. 10 refs., 1 fig., 27 tabs.« less

Electricity exchange and the valuation of transnational transmission access: A case study of intra-regional integration of the electric industries of Argentina and Chile

NASA Astrophysics Data System (ADS)

Brereton, Beverly Ann

The interconnection of neighboring electricity networks provides opportunities for the realization of synergies between electricity systems. Examples of the synergies to be realized are the rationalized management of the electricity networks whose fuel source domination differs, and the exploitation of non-coincident system peak demands. These factors allow technology diversity in the satisfaction of electricity demand, the coordination of planning and maintenance schedules between the networks by exploiting the cost differences in the pool of generation assets and the load configuration differences in the neighboring locations. The interconnection decision studied in this dissertation focused on the electricity networks of Argentina and Chile whose electricity systems operate in isolation at the current time. The cooperative game-theoretic framework was applied in the analysis of the decision facing the two countries and the net surplus to be derived from interconnection was evaluated. Measurement of the net gains from interconnection used in this study were reflected in changes in generating costs under the assumption that demand is fixed under all scenarios. With the demand for electricity assumed perfectly inelastic, passive or aggressive bidding strategies were considered under the scenarios for the generators in the two countries. The interconnection decision was modeled using a linear power flow model which utilizes linear programming techniques to reflect dispatch procedures based on generation bids. Results of the study indicate that the current interconnection project between Argentina and Chile will not result in positive net surplus under a variety of scenarios. Only under significantly reduced interconnection cost will the venture prove attractive. Possible sharing mechanisms were also explored in the research and a symmetric distribution of the net surplus to be derived under the reduced interconnection cost scenario was recommended to preserve equity in the allocation of the interconnection gains.

RadNet Air Data From Honolulu, HI

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RadNet Air Data From Birmingham, AL

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RadNet Air Data From Dallas, TX

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RadNet Air Data From Omaha, NE

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RadNet Air Data From Montgomery, AL

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RadNet Air Data From Burlington, VT

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RadNet Air Data From Washington, DC

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RadNet Air Data From Rochester, NY

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RadNet Air Data From Tampa, FL

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RadNet Air Data From Cincinnati, OH

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RadNet Air Data From Fairbanks, AK

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RadNet Air Data From Yuma, AZ

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RadNet Air Data From Kalispell, MT

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RadNet Air Data From Kearney, NE

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RadNet Air Data From Phoenix, AZ

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RadNet Air Data From Pierre, SD

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RadNet Air Data From Augusta, GA

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RadNet Air Data From Syracuse, NY

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RadNet Air Data From Albany, NY

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RadNet Air Data From Anchorage, AK

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RadNet Air Data From Philadelphia, PA

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RadNet Air Data From Houston, TX

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RadNet Air Data From Duluth, MN

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RadNet Air Data From Raleigh, NC

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RadNet Air Data From Louisville, KY

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RadNet Air Data From Cleveland, OH

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RadNet Air Data From Carlsbad, NM

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RadNet Air Data From Corvallis, OR

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RadNet Air Data From Orono, ME

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RadNet Air Data From Reno, NV

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RadNet Air Data From Nashville, TN

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RadNet Air Data From Concord, NH

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RadNet Air Data From Paducah, KY

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RadNet Air Data From Edison, NJ

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RadNet Air Data From Wilmington, NC

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RadNet Air Data From Boise, ID

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RadNet Air Data From Albuquerque, NM

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RadNet Air Data From Fresno, CA

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RadNet Air Data From Amarillo, TX

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RadNet Air Data From Portland, OR

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RadNet Air Data From Jacksonville, FL

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RadNet Air Data From Dover, DE

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RadNet Air Data From Baltimore, MD

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RadNet Air Data From Miami, FL

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RadNet Air Data From Billings, MT

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RadNet Air Data From Providence, RI

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RadNet Air Data From Knoxville, TN

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RadNet Air Data From Columbus, OH

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RadNet Air Data From Bloomsburg, PA

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RadNet Air Data From Shreveport, LA

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RadNet Air Data From Laredo, TX

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RadNet Air Data From Bakersfield, CA

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RadNet Air Data From Portland, ME

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RadNet Air Data From Champaign, IL

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Champaign, IL from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Tucson, AZ

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Tucson, AZ from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Juneau, AK

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Juneau, AK from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Toledo, OH

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Toledo, OH from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Boston, MA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Boston, MA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Indianapolis, IN

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Indianapolis, IN from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Yaphank, NY

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Yaphank, NY from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Anaheim, CA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Anaheim, CA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Riverside, CA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Riverside, CA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Detroit, MI

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Detroit, MI from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Wichita, KS

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Wichita, KS from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Columbia, SC

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Columbia, SC from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Milwaukee, WI

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Milwaukee, WI from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Richmond, VA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Richmond, VA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Tulsa, OK

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Tulsa, OK from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Aurora, IL

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Aurora, IL from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Hartford, CT

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Hartford. CT from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Charleston, WV

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Charleston, WV from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Shawano, WI

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Shawano, WI from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Harlingen, TX

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Harlingen, TX from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation

RadNet Air Data From Springfield, MO

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Springfield, MO from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Olympia, WA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Olympia, WA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Memphis, TN

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Memphis, TN from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Lubbock, TX

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Lubbock, TX from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Sacramento, CA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Sacramento, CA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Lockport, NY

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Lockport, NY from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Jackson, MS

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Jackson, MS from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Seattle, WA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Seattle, WA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Pittsburgh, PA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Pittsburgh, PA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Madison, WI

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Madison, WI from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Ellensburg, WA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Ellensburg, WA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Harrisonburg, VA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Harrisonburg, VA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Bismarck, ND

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Bismarck, ND from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Denver, CO

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Denver, CO from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Charlotte, NC

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Charlotte, NC from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Lexington, KY

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Lexington, KY from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Casper, WY

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Casper, WY from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Eureka, CA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Eureka, CA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Lincoln, NE

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Lincoln, NE from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Orlando, FL

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Orlando, FL from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Mobile, AL

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Mobile, AL from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Spokane, WA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Spokane, WA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Atlanta, GA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Atlanta, GA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Greensboro, NC

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Greensboro, NC from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Chicago, IL

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Chicago, IL from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Worcester, MA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Worcester, MA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Austin, TX

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Austin, TX from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

EMODNet Bathymetry - building and providing a high resolution digital bathymetry for European seas

NASA Astrophysics Data System (ADS)

Schaap, Dick M. A.

2016-04-01

Access to marine data is a key issue for the EU Marine Strategy Framework Directive and the EU Marine Knowledge 2020 agenda and includes the European Marine Observation and Data Network (EMODNet) initiative. EMODNet aims at assembling European marine data, data products and metadata from diverse sources in a uniform way. The EMODNet data infrastructure is developed through a stepwise approach in three major phases. Currently EMODNet is entering its 3rd phase with operational portals providing access to marine data for bathymetry, geology, physics, chemistry, biology, seabed habitats and human activities, complemented by checkpoint projects, analyzing the fitness for purpose of data provision. The EMODNet Bathymetry project develops and publishes Digital Terrain Models (DTM) for the European seas. These are produced from survey and aggregated data sets that are indexed with metadata by adopting from SeaDataNet the Common Data Index (CDI) data discovery and access service and the Sextant data products catalogue service. SeaDataNet is a network of major oceanographic data centers around the European seas that manage, operate and further develop a pan-European infrastructure for marine and ocean data management. SeaDataNet is also setting and governing marine data standards, and exploring and establishing interoperability solutions to connect to other e-infrastructures on the basis of standards such as ISO and OGC. The SeaDataNet portal provides users a number of interrelated meta directories, an extensive range of controlled vocabularies, and the various SeaDataNet standards and tools. SeaDataNet at present gives overview and access to more than 1.8 million data sets for physical oceanography, chemistry, geology, geophysics, bathymetry and biology from more than 100 connected data centers from 34 countries riparian to European seas. The latest EMODNet Bathymetry DTM has a resolution of 1/8 arc minute * 1/8 arc minute and covers all European sea regions. Use is made of available and gathered surveys and already more than 13.000 surveys have been indexed by 27 European data providers from 15 countries and originating from more than 120 organizations. Also use is made of composite DTMs as generated and maintained by several data providers for their areas of interest. Already 44 composite DTMs are included in the Sextant data products catalogue. For areas without coverage use is made of the latest global DTM of GEBCO who is partner in the EMODNet Bathymetry project. In return GEBCO integrates the EMODNet DTM to achieve an enriched and better result. The catalogue services and the generated EMODNet can be queried and browsed at the dedicated EMODNet Bathymetry portal which also provides a versatile DTM viewing service with many relevant map layers and functions for retrieving. Activities are underway for further refinement following user feedback. The EMODnet DTM is publicly available for downloading in various formats. The presentation will highlight key details of EMODNet Bathymetry project, the recently released EMODNet Digital Bathymetry for all European seas, its portal and its versatile viewer.

AdaNET executive summary

NASA Technical Reports Server (NTRS)

Digman, R. Michael

1988-01-01

The goal of AdaNET is to transfer existing and emerging software engineering technology from the Federal government to the private sector. The views and perspectives of the current project participants on long and short term goals for AdaNET; organizational structure; resources and returns; summary of identified AdaNET services; and the summary of the organizational model currently under discussion are presented.

State-based verification of RTCP-nets with nuXmv

NASA Astrophysics Data System (ADS)

Biernacka, Agnieszka; Biernacki, Jerzy; Szpyrka, Marcin

2015-12-01

The paper deals with an algorithm of translation of RTCP-nets' (real-time coloured Petri nets) coverability graphs into nuXmv state machines. The approach enables users to verify RTCP-nets with model checking techniques provided by the nuXmv tool. Full details of the algorithm are presented and an illustrative example of the approach usefulness is provided.

Peptidylarginine deiminase 4: a nuclear button triggering neutrophil extracellular traps in inflammatory diseases and aging.

PubMed

Wong, Siu Ling; Wagner, Denisa D

2018-06-20

Peptidylarginine deiminase 4 (PAD4) is a nuclear citrullinating enzyme that is critically involved in the release of decondensed chromatin from neutrophils as neutrophil extracellular traps (NETs). NETs, together with fibrin, are implicated in host defense against pathogens; however, the formation of NETs (NETosis) has injurious effects that may outweigh their protective role. For example, PAD4 activity produces citrullinated neoantigens that promote autoimmune diseases, such as rheumatoid arthritis, to which PAD4 is genetically linked and where NETosis is prominent. NETs are also generated in basic sterile inflammatory responses that are induced by many inflammatory stimuli, including cytokines, hypoxia, and activated platelets. Mice that lack PAD4-deficient in NETosis-serve as an excellent tool with which to study the importance of NETs in disease models. In recent years, animal and human studies have demonstrated that NETs contribute to the etiology and propagation of many common noninfectious diseases, the focus of our review. We will discuss the role of NETs in thrombotic and cardiovascular disease, the induction of NETs by cancers and its implications for cancer progression and cancer-associated thrombosis, and elevated NETosis in diabetes and its negative impact on wound healing, and will propose a link between PAD4/NETs and age-related organ fibrosis. We identify unresolved issues and new research directions.-Wong, S. L., Wagner, D. D. Peptidylarginine deiminase 4: a nuclear button triggering neutrophil extracellular traps in inflammatory diseases and aging.

Fluid Stochastic Petri Nets: Theory, Applications, and Solution

NASA Technical Reports Server (NTRS)

Horton, Graham; Kulkarni, Vidyadhar G.; Nicol, David M.; Trivedi, Kishor S.

1996-01-01

In this paper we introduce a new class of stochastic Petri nets in which one or more places can hold fluid rather than discrete tokens. We define a class of fluid stochastic Petri nets in such a way that the discrete and continuous portions may affect each other. Following this definition we provide equations for their transient and steady-state behavior. We present several examples showing the utility of the construct in communication network modeling and reliability analysis, and discuss important special cases. We then discuss numerical methods for computing the transient behavior of such nets. Finally, some numerical examples are presented.

Computational model for calculating the dynamical behaviour of generators caused by unbalanced magnetic pull and experimental validation

NASA Astrophysics Data System (ADS)

Pennacchi, Paolo

2008-04-01

The modelling of the unbalanced magnetic pull (UMP) in generators and the experimental validation of the proposed method are presented in this paper. The UMP is one of the most remarkable effects of electromechanical interactions in rotating machinery. As a consequence of the rotor eccentricity, the imbalance of the electromagnetic forces acting between rotor and stator generates a net radial force. This phenomenon can be avoided by means of a careful assembly and manufacture in small and stiff machines, like electrical motors. On the contrary, the eccentricity of the active part of the rotor with respect to the stator is unavoidable in big generators of power plants, because they operate above their first critical speed and are supported by oil-film bearings. In the first part of the paper, a method aimed to calculate the UMP force is described. This model is more general than those available in literature, which are limited to circular orbits. The model is based on the actual position of the rotor inside the stator, therefore on the actual air-gap distribution, regardless of the orbit type. The closed form of the nonlinear UMP force components is presented. In the second part, the experimental validation of the proposed model is presented. The dynamical behaviour in the time domain of a steam turbo-generator of a power plant is considered and it is shown that the model is able to reproduce the dynamical effects due to the excitation of the magnetic field in the generator.

Carbon Dynamics of Bioenergy Cropping Systems Compared to Conventional Cotton Cropping Systems in the Southern Cotton Belt Region of the U.S.

NASA Astrophysics Data System (ADS)

Rajan, N.; Sharma, S.; Casey, K.; Maas, S. J.

2015-12-01

We are facing an unprecedented challenge in securing America's energy future. To address this challenge, increased biofuel crop production is needed. Second-generation biofuels are made from the by-products of intensive agriculture or from less-intensive agriculture on more marginal lands. The Southwestern U.S. Cotton Belt can play a significant role in this effort through a change from more conventional crops (like continuous cotton) to second-generation biofuel feedstocks (biomass sorghum and perennial grasses). We have established eddy covariance flux towers in producer fields in the Southern High Plains region. Among the four land uses compared, the net carbon uptake was the highest for the biomass sorghum field. During the year 2014, the biomass sorghum field gained approximately 672 gC m-2y-1. The next highest carbon uptake was recorded for the Old World Bluestem grass field, which was approximately 301 gC m-2y-1. The dominant land use in the region is cotton. While the forage sorghum and grass fields acted as net carbon sinks, the irrigated cotton field acted as a net carbon source to the atmosphere during the same period. The irrigated cotton field exhibited a net carbon loss of approximately 246 gC m-2y-1. In contrast, the dryland cotton field acted as a net carbon sink, with a total uptake of approximately 58 g C m-2y-1. The net primary production of the irrigated cotton field was higher than that of the dryland cotton field, yet the irrigated field was a significant carbon source to the atmosphere. This was due to conventional tillage practices combined with irrigation which enhanced the ecosystem respiration significantly compared to the dryland field. In 2014, an early spring cold front caused poor germination of seeds in the majority of the cotton fields in the region, including the eddy covariance site. This site was re-planted on 9 June, which shortened the growing season for cotton. This was also a contributing factor to this field being a net carbon source. When only seasonal data were considered (i.e, from planting to harvest), the biomass sorghum field was the largest net C sink (-668 g C m-2y-1) followed by the grassland field (-298 g C m-2y-1). Among the two cotton fields, the irrigated cotton field remained a net carbon source (38 g C m-2y-1), while the dryland field was a net carbon sink (-127 g C m-2y-1).

A new type of polyhedron-based metal-organic frameworks with interpenetrating cationic and anionic nets demonstrating ion exchange, adsorption and luminescent properties.

PubMed

Zhang, Zheng-Jie; Shi, Wei; Niu, Zheng; Li, Huan-Huan; Zhao, Bin; Cheng, Peng; Liao, Dai-Zheng; Yan, Shi-Ping

2011-06-14

An interesting new MOF, built with interpenetrating cationic (MOF-A(+)) and anionic (MOF-B(-)) nets that do not require counter ions to balance charge, together with an architectural strategy focused on the use of MOPs as nodes and MOCs as spacers for the generation of 3D frameworks, is reported. This journal is © The Royal Society of Chemistry 2011

Advanced typical and atypical carcinoid tumours of the lung: management recommendations

PubMed Central

Melosky, B.

2018-01-01

Background Neuroendocrine tumours (nets) are classified by site of origin, with lung being the second most common primary site after the gastrointestinal tract. Lung nets are rare and heterogeneous, with varied pathologic and clinical features. Typical and atypical carcinoid tumours are low-grade lung nets which, compared with the more common high-grade nets, are associated with a more favourable prognosis. Still, optimal treatment strategies are lacking. Methods This review concentrates on classification and treatment strategies for metastatic low-grade lung nets, considering both typical and atypical carcinoids. The terminology can be confusing, and an attempt is made to simplify it. Promising results from recent trials that included lung nets are presented and discussed. Finally, guidelines from Europe and North America are discussed, and differences are noted. Results Even within the group of patients with low-grade nets, the presentation, the locations of metastasis, and the speed of progression can be very different. The initial work-up and an understanding of the tumour’s biology are key in making management decisions. Various treatment options—including somatostatin analogs, peptide receptor radioligand therapy, and biologic systemic therapy, specifically with the mtor (mechanistic target of rapamycin) inhibitor everolimus—are now available and are presented in a treatment algorithm. Summary Although lung nets are rare and evidence supporting optimal treatment strategies is lacking, the recent publication of trials that have included patients with lung nets advances evidence-based therapy for these tumours. Many variables have to be considered in managing these tumours that have received little attention. Education for treating physicians is needed.

RadNet Air Data From San Juan, PR

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for San Juan, PR from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Grand Rapids, MI

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Grand Rapids, MI from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Corpus Christi, TX

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Corpus Christi, TX from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Little Rock, AR

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Little Rock, AR from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Des Moines, IA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Des Moines, IA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Fort Madison, IA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Fort Madison, IA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Fort Wayne, IN

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Fort Wayne, IN from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Navajo Lake, NM

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This page presents radiation air monitoring and air filter analysis data for Navajo Lake, NM from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Las Vegas, NV

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This page presents radiation air monitoring and air filter analysis data for Las Vegas, NV from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From St. George, UT

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This page presents radiation air monitoring and air filter analysis data for St. George, UT from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Jefferson City, MO

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This page presents radiation air monitoring and air filter analysis data for Jefferson City, MO from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Fort Worth, TX

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This page presents radiation air monitoring and air filter analysis data for Fort Worth, TX from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Kansas City, KS

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Kansas City, KS from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From San Angelo, TX

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This page presents radiation air monitoring and air filter analysis data for San Angelo, TX from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From San Francisco, CA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for San Francisco, CA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Oklahoma City, OK

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This page presents radiation air monitoring and air filter analysis data for Oklahoma City, OK from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From San Bernardino, CA

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This page presents radiation air monitoring and air filter analysis data for San Bernardino, CA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Idaho Falls, ID

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This page presents radiation air monitoring and air filter analysis data for Idaho Falls, ID from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Los Angeles, CA

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This page presents radiation air monitoring and air filter analysis data for Los Angeles, CA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From El Paso, TX

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This page presents radiation air monitoring and air filter analysis data for El Paso, TX from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Grand Junction, CO

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This page presents radiation air monitoring and air filter analysis data for Grand Junction, CO from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From St. Paul, MN

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RadNet Air Data From Virginia Beach, VA

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RadNet Air Data From La Crosse, WI

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RadNet Air Data From San Diego, CA

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RadNet Air Data From San Jose, CA

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RadNet Air Data From San Antonio, TX

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This page presents radiation air monitoring and air filter analysis data for San Antonio, TX from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Rapid City, SD

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RadNet Air Data From Dodge City, KS

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This page presents radiation air monitoring and air filter analysis data for Dodge City, KS from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Colorado Springs, CO

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RadNet Air Data From St. Louis, MO

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RadNet Air Data From Bay City, MI

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Bay City, MI from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Mason City, IA

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Mason City, IA from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.

RadNet Air Data From Fort Smith, AR

EPA Pesticide Factsheets

This page presents radiation air monitoring and air filter analysis data for Fort Smith, AR from EPA's RadNet system. RadNet is a nationwide network of monitoring stations that measure radiation in air, drinking water and precipitation.