Sample records for network visualization system

  1. A topology visualization early warning distribution algorithm for large-scale network security incidents.

    PubMed

    He, Hui; Fan, Guotao; Ye, Jianwei; Zhang, Weizhe

    2013-01-01

    It is of great significance to research the early warning system for large-scale network security incidents. It can improve the network system's emergency response capabilities, alleviate the cyber attacks' damage, and strengthen the system's counterattack ability. A comprehensive early warning system is presented in this paper, which combines active measurement and anomaly detection. The key visualization algorithm and technology of the system are mainly discussed. The large-scale network system's plane visualization is realized based on the divide and conquer thought. First, the topology of the large-scale network is divided into some small-scale networks by the MLkP/CR algorithm. Second, the sub graph plane visualization algorithm is applied to each small-scale network. Finally, the small-scale networks' topologies are combined into a topology based on the automatic distribution algorithm of force analysis. As the algorithm transforms the large-scale network topology plane visualization problem into a series of small-scale network topology plane visualization and distribution problems, it has higher parallelism and is able to handle the display of ultra-large-scale network topology.

  2. Visual analysis and exploration of complex corporate shareholder networks

    NASA Astrophysics Data System (ADS)

    Tekušová, Tatiana; Kohlhammer, Jörn

    2008-01-01

    The analysis of large corporate shareholder network structures is an important task in corporate governance, in financing, and in financial investment domains. In a modern economy, large structures of cross-corporation, cross-border shareholder relationships exist, forming complex networks. These networks are often difficult to analyze with traditional approaches. An efficient visualization of the networks helps to reveal the interdependent shareholding formations and the controlling patterns. In this paper, we propose an effective visualization tool that supports the financial analyst in understanding complex shareholding networks. We develop an interactive visual analysis system by combining state-of-the-art visualization technologies with economic analysis methods. Our system is capable to reveal patterns in large corporate shareholder networks, allows the visual identification of the ultimate shareholders, and supports the visual analysis of integrated cash flow and control rights. We apply our system on an extensive real-world database of shareholder relationships, showing its usefulness for effective visual analysis.

  3. ProteoLens: a visual analytic tool for multi-scale database-driven biological network data mining.

    PubMed

    Huan, Tianxiao; Sivachenko, Andrey Y; Harrison, Scott H; Chen, Jake Y

    2008-08-12

    New systems biology studies require researchers to understand how interplay among myriads of biomolecular entities is orchestrated in order to achieve high-level cellular and physiological functions. Many software tools have been developed in the past decade to help researchers visually navigate large networks of biomolecular interactions with built-in template-based query capabilities. To further advance researchers' ability to interrogate global physiological states of cells through multi-scale visual network explorations, new visualization software tools still need to be developed to empower the analysis. A robust visual data analysis platform driven by database management systems to perform bi-directional data processing-to-visualizations with declarative querying capabilities is needed. We developed ProteoLens as a JAVA-based visual analytic software tool for creating, annotating and exploring multi-scale biological networks. It supports direct database connectivity to either Oracle or PostgreSQL database tables/views, on which SQL statements using both Data Definition Languages (DDL) and Data Manipulation languages (DML) may be specified. The robust query languages embedded directly within the visualization software help users to bring their network data into a visualization context for annotation and exploration. ProteoLens supports graph/network represented data in standard Graph Modeling Language (GML) formats, and this enables interoperation with a wide range of other visual layout tools. The architectural design of ProteoLens enables the de-coupling of complex network data visualization tasks into two distinct phases: 1) creating network data association rules, which are mapping rules between network node IDs or edge IDs and data attributes such as functional annotations, expression levels, scores, synonyms, descriptions etc; 2) applying network data association rules to build the network and perform the visual annotation of graph nodes and edges according to associated data values. We demonstrated the advantages of these new capabilities through three biological network visualization case studies: human disease association network, drug-target interaction network and protein-peptide mapping network. The architectural design of ProteoLens makes it suitable for bioinformatics expert data analysts who are experienced with relational database management to perform large-scale integrated network visual explorations. ProteoLens is a promising visual analytic platform that will facilitate knowledge discoveries in future network and systems biology studies.

  4. Technical note: real-time web-based wireless visual guidance system for radiotherapy.

    PubMed

    Lee, Danny; Kim, Siyong; Palta, Jatinder R; Kim, Taeho

    2017-06-01

    Describe a Web-based wireless visual guidance system that mitigates issues associated with hard-wired audio-visual aided patient interactive motion management systems that are cumbersome to use in routine clinical practice. Web-based wireless visual display duplicates an existing visual display of a respiratory-motion management system for visual guidance. The visual display of the existing system is sent to legacy Web clients over a private wireless network, thereby allowing a wireless setting for real-time visual guidance. In this study, active breathing coordinator (ABC) trace was used as an input for visual display, which captured and transmitted to Web clients. Virtual reality goggles require two (left and right eye view) images for visual display. We investigated the performance of Web-based wireless visual guidance by quantifying (1) the network latency of visual displays between an ABC computer display and Web clients of a laptop, an iPad mini 2 and an iPhone 6, and (2) the frame rate of visual display on the Web clients in frames per second (fps). The network latency of visual display between the ABC computer and Web clients was about 100 ms and the frame rate was 14.0 fps (laptop), 9.2 fps (iPad mini 2) and 11.2 fps (iPhone 6). In addition, visual display for virtual reality goggles was successfully shown on the iPhone 6 with 100 ms and 11.2 fps. A high network security was maintained by utilizing the private network configuration. This study demonstrated that a Web-based wireless visual guidance can be a promising technique for clinical motion management systems, which require real-time visual display of their outputs. Based on the results of this study, our approach has the potential to reduce clutter associated with wired-systems, reduce space requirements, and extend the use of medical devices from static usage to interactive and dynamic usage in a radiotherapy treatment vault.

  5. Alerts Visualization and Clustering in Network-based Intrusion Detection

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, Dr. Li; Gasior, Wade C; Dasireddy, Swetha

    2010-04-01

    Today's Intrusion detection systems when deployed on a busy network overload the network with huge number of alerts. This behavior of producing too much raw information makes it less effective. We propose a system which takes both raw data and Snort alerts to visualize and analyze possible intrusions in a network. Then we present with two models for the visualization of clustered alerts. Our first model gives the network administrator with the logical topology of the network and detailed information of each node that involves its associated alerts and connections. In the second model, flocking model, presents the network administratormore » with the visual representation of IDS data in which each alert is represented in different color and the alerts with maximum similarity move together. This gives network administrator with the idea of detecting various of intrusions through visualizing the alert patterns.« less

  6. FROMS3D: New Software for 3-D Visualization of Fracture Network System in Fractured Rock Masses

    NASA Astrophysics Data System (ADS)

    Noh, Y. H.; Um, J. G.; Choi, Y.

    2014-12-01

    A new software (FROMS3D) is presented to visualize fracture network system in 3-D. The software consists of several modules that play roles in management of borehole and field fracture data, fracture network modelling, visualization of fracture geometry in 3-D and calculation and visualization of intersections and equivalent pipes between fractures. Intel Parallel Studio XE 2013, Visual Studio.NET 2010 and the open source VTK library were utilized as development tools to efficiently implement the modules and the graphical user interface of the software. The results have suggested that the developed software is effective in visualizing 3-D fracture network system, and can provide useful information to tackle the engineering geological problems related to strength, deformability and hydraulic behaviors of the fractured rock masses.

  7. A neural-visualization IDS for honeynet data.

    PubMed

    Herrero, Álvaro; Zurutuza, Urko; Corchado, Emilio

    2012-04-01

    Neural intelligent systems can provide a visualization of the network traffic for security staff, in order to reduce the widely known high false-positive rate associated with misuse-based Intrusion Detection Systems (IDSs). Unlike previous work, this study proposes an unsupervised neural models that generate an intuitive visualization of the captured traffic, rather than network statistics. These snapshots of network events are immensely useful for security personnel that monitor network behavior. The system is based on the use of different neural projection and unsupervised methods for the visual inspection of honeypot data, and may be seen as a complementary network security tool that sheds light on internal data structures through visual inspection of the traffic itself. Furthermore, it is intended to facilitate verification and assessment of Snort performance (a well-known and widely-used misuse-based IDS), through the visualization of attack patterns. Empirical verification and comparison of the proposed projection methods are performed in a real domain, where two different case studies are defined and analyzed.

  8. Smart unattended sensor networks with scene understanding capabilities

    NASA Astrophysics Data System (ADS)

    Kuvich, Gary

    2006-05-01

    Unattended sensor systems are new technologies that are supposed to provide enhanced situation awareness to military and law enforcement agencies. A network of such sensors cannot be very effective in field conditions only if it can transmit visual information to human operators or alert them on motion. In the real field conditions, events may happen in many nodes of a network simultaneously. But the real number of control personnel is always limited, and attention of human operators can be simply attracted to particular network nodes, while more dangerous threat may be unnoticed at the same time in the other nodes. Sensor networks would be more effective if equipped with a system that is similar to human vision in its abilities to understand visual information. Human vision uses for that a rough but wide peripheral system that tracks motions and regions of interests, narrow but precise foveal vision that analyzes and recognizes objects in the center of selected region of interest, and visual intelligence that provides scene and object contexts and resolves ambiguity and uncertainty in the visual information. Biologically-inspired Network-Symbolic models convert image information into an 'understandable' Network-Symbolic format, which is similar to relational knowledge models. The equivalent of interaction between peripheral and foveal systems in the network-symbolic system is achieved via interaction between Visual and Object Buffers and the top-level knowledge system.

  9. Software For Graphical Representation Of A Network

    NASA Technical Reports Server (NTRS)

    Mcallister, R. William; Mclellan, James P.

    1993-01-01

    System Visualization Tool (SVT) computer program developed to provide systems engineers with means of graphically representing networks. Generates diagrams illustrating structures and states of networks defined by users. Provides systems engineers powerful tool simplifing analysis of requirements and testing and maintenance of complex software-controlled systems. Employs visual models supporting analysis of chronological sequences of requirements, simulation data, and related software functions. Applied to pneumatic, hydraulic, and propellant-distribution networks. Used to define and view arbitrary configurations of such major hardware components of system as propellant tanks, valves, propellant lines, and engines. Also graphically displays status of each component. Advantage of SVT: utilizes visual cues to represent configuration of each component within network. Written in Turbo Pascal(R), version 5.0.

  10. Real-Time Visualization of Network Behaviors for Situational Awareness

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Best, Daniel M.; Bohn, Shawn J.; Love, Douglas V.

    Plentiful, complex, and dynamic data make understanding the state of an enterprise network difficult. Although visualization can help analysts understand baseline behaviors in network traffic and identify off-normal events, visual analysis systems often do not scale well to operational data volumes (in the hundreds of millions to billions of transactions per day) nor to analysis of emergent trends in real-time data. We present a system that combines multiple, complementary visualization techniques coupled with in-stream analytics, behavioral modeling of network actors, and a high-throughput processing platform called MeDICi. This system provides situational understanding of real-time network activity to help analysts takemore » proactive response steps. We have developed these techniques using requirements gathered from the government users for which the tools are being developed. By linking multiple visualization tools to a streaming analytic pipeline, and designing each tool to support a particular kind of analysis (from high-level awareness to detailed investigation), analysts can understand the behavior of a network across multiple levels of abstraction.« less

  11. A survey of visualization systems for network security.

    PubMed

    Shiravi, Hadi; Shiravi, Ali; Ghorbani, Ali A

    2012-08-01

    Security Visualization is a very young term. It expresses the idea that common visualization techniques have been designed for use cases that are not supportive of security-related data, demanding novel techniques fine tuned for the purpose of thorough analysis. Significant amount of work has been published in this area, but little work has been done to study this emerging visualization discipline. We offer a comprehensive review of network security visualization and provide a taxonomy in the form of five use-case classes encompassing nearly all recent works in this area. We outline the incorporated visualization techniques and data sources and provide an informative table to display our findings. From the analysis of these systems, we examine issues and concerns regarding network security visualization and provide guidelines and directions for future researchers and visual system developers.

  12. A Multilevel Gamma-Clustering Layout Algorithm for Visualization of Biological Networks

    PubMed Central

    Hruz, Tomas; Lucas, Christoph; Laule, Oliver; Zimmermann, Philip

    2013-01-01

    Visualization of large complex networks has become an indispensable part of systems biology, where organisms need to be considered as one complex system. The visualization of the corresponding network is challenging due to the size and density of edges. In many cases, the use of standard visualization algorithms can lead to high running times and poorly readable visualizations due to many edge crossings. We suggest an approach that analyzes the structure of the graph first and then generates a new graph which contains specific semantic symbols for regular substructures like dense clusters. We propose a multilevel gamma-clustering layout visualization algorithm (MLGA) which proceeds in three subsequent steps: (i) a multilevel γ-clustering is used to identify the structure of the underlying network, (ii) the network is transformed to a tree, and (iii) finally, the resulting tree which shows the network structure is drawn using a variation of a force-directed algorithm. The algorithm has a potential to visualize very large networks because it uses modern clustering heuristics which are optimized for large graphs. Moreover, most of the edges are removed from the visual representation which allows keeping the overview over complex graphs with dense subgraphs. PMID:23864855

  13. Research on the framework and key technologies of panoramic visualization for smart distribution network

    NASA Astrophysics Data System (ADS)

    Du, Jian; Sheng, Wanxing; Lin, Tao; Lv, Guangxian

    2018-05-01

    Nowadays, the smart distribution network has made tremendous progress, and the business visualization becomes even more significant and indispensable. Based on the summarization of traditional visualization technologies and demands of smart distribution network, a panoramic visualization application is proposed in this paper. The overall architecture, integrated architecture and service architecture of panoramic visualization application is firstly presented. Then, the architecture design and main functions of panoramic visualization system are elaborated in depth. In addition, the key technologies related to the application is discussed briefly. At last, two typical visualization scenarios in smart distribution network, which are risk warning and fault self-healing, proves that the panoramic visualization application is valuable for the operation and maintenance of the distribution network.

  14. Connectopathy in Autism Spectrum Disorders: A Review of Evidence from Visual Evoked Potentials and Diffusion Magnetic Resonance Imaging

    PubMed Central

    Yamasaki, Takao; Maekawa, Toshihiko; Fujita, Takako; Tobimatsu, Shozo

    2017-01-01

    Individuals with autism spectrum disorder (ASD) show superior performance in processing fine details; however, they often exhibit impairments of gestalt face, global motion perception, and visual attention as well as core social deficits. Increasing evidence has suggested that social deficits in ASD arise from abnormal functional and structural connectivities between and within distributed cortical networks that are recruited during social information processing. Because the human visual system is characterized by a set of parallel, hierarchical, multistage network systems, we hypothesized that the altered connectivity of visual networks contributes to social cognition impairment in ASD. In the present review, we focused on studies of altered connectivity of visual and attention networks in ASD using visual evoked potentials (VEPs), event-related potentials (ERPs), and diffusion tensor imaging (DTI). A series of VEP, ERP, and DTI studies conducted in our laboratory have demonstrated complex alterations (impairment and enhancement) of visual and attention networks in ASD. Recent data have suggested that the atypical visual perception observed in ASD is caused by altered connectivity within parallel visual pathways and attention networks, thereby contributing to the impaired social communication observed in ASD. Therefore, we conclude that the underlying pathophysiological mechanism of ASD constitutes a “connectopathy.” PMID:29170625

  15. Glyph-based generic network visualization

    NASA Astrophysics Data System (ADS)

    Erbacher, Robert F.

    2002-03-01

    Network managers and system administrators have an enormous task set before them in this day of growing network usage. This is particularly true of e-commerce companies and others dependent on a computer network for their livelihood. Network managers and system administrators must monitor activity for intrusions and misuse while at the same time monitoring performance of the network. In this paper, we describe our visualization techniques for assisting in the monitoring of networks for both of these tasks. The goal of these visualization techniques is to integrate the visual representation of both network performance/usage as well as data relevant to intrusion detection. The main difficulties arise from the difference in the intrinsic data and layout needs of each of these tasks. Glyph based techniques are additionally used to indicate the representative values of the necessary data parameters over time. Additionally, our techniques are geared towards providing an environment that can be used continuously for constant real-time monitoring of the network environment.

  16. Toward a Scalable Visualization System for Network Traffic Monitoring

    NASA Astrophysics Data System (ADS)

    Malécot, Erwan Le; Kohara, Masayoshi; Hori, Yoshiaki; Sakurai, Kouichi

    With the multiplication of attacks against computer networks, system administrators are required to monitor carefully the traffic exchanged by the networks they manage. However, that monitoring task is increasingly laborious because of the augmentation of the amount of data to analyze. And that trend is going to intensify with the explosion of the number of devices connected to computer networks along with the global rise of the available network bandwidth. So system administrators now heavily rely on automated tools to assist them and simplify the analysis of the data. Yet, these tools provide limited support and, most of the time, require highly skilled operators. Recently, some research teams have started to study the application of visualization techniques to the analysis of network traffic data. We believe that this original approach can also allow system administrators to deal with the large amount of data they have to process. In this paper, we introduce a tool for network traffic monitoring using visualization techniques that we developed in order to assist the system administrators of our corporate network. We explain how we designed the tool and some of the choices we made regarding the visualization techniques to use. The resulting tool proposes two linked representations of the network traffic and activity, one in 2D and the other in 3D. As 2D and 3D visualization techniques have different assets, we resulted in combining them in our tool to take advantage of their complementarity. We finally tested our tool in order to evaluate the accuracy of our approach.

  17. OmicsNet: a web-based tool for creation and visual analysis of biological networks in 3D space.

    PubMed

    Zhou, Guangyan; Xia, Jianguo

    2018-06-07

    Biological networks play increasingly important roles in omics data integration and systems biology. Over the past decade, many excellent tools have been developed to support creation, analysis and visualization of biological networks. However, important limitations remain: most tools are standalone programs, the majority of them focus on protein-protein interaction (PPI) or metabolic networks, and visualizations often suffer from 'hairball' effects when networks become large. To help address these limitations, we developed OmicsNet - a novel web-based tool that allows users to easily create different types of molecular interaction networks and visually explore them in a three-dimensional (3D) space. Users can upload one or multiple lists of molecules of interest (genes/proteins, microRNAs, transcription factors or metabolites) to create and merge different types of biological networks. The 3D network visualization system was implemented using the powerful Web Graphics Library (WebGL) technology that works natively in most major browsers. OmicsNet supports force-directed layout, multi-layered perspective layout, as well as spherical layout to help visualize and navigate complex networks. A rich set of functions have been implemented to allow users to perform coloring, shading, topology analysis, and enrichment analysis. OmicsNet is freely available at http://www.omicsnet.ca.

  18. A Network and Visual Quality Aware N-Screen Content Recommender System Using Joint Matrix Factorization

    PubMed Central

    Ullah, Farman; Sarwar, Ghulam; Lee, Sungchang

    2014-01-01

    We propose a network and visual quality aware N-Screen content recommender system. N-Screen provides more ways than ever before to access multimedia content through multiple devices and heterogeneous access networks. The heterogeneity of devices and access networks present new questions of QoS (quality of service) in the realm of user experience with content. We propose, a recommender system that ensures a better visual quality on user's N-screen devices and the efficient utilization of available access network bandwidth with user preferences. The proposed system estimates the available bandwidth and visual quality on users N-Screen devices and integrates it with users preferences and contents genre information to personalize his N-Screen content. The objective is to recommend content that the user's N-Screen device and access network are capable of displaying and streaming with the user preferences that have not been supported in existing systems. Furthermore, we suggest a joint matrix factorization approach to jointly factorize the users rating matrix with the users N-Screen device similarity and program genres similarity. Finally, the experimental results show that we also enhance the prediction and recommendation accuracy, sparsity, and cold start issues. PMID:24982999

  19. A Dynamic Three-Dimensional Network Visualization Program for Integration into CyberCIEGE and Other Network Visualization Scenarios

    DTIC Science & Technology

    2007-06-01

    information flow involved in network attacks. This kind of information can be invaluable in learning how to best setup and defend computer networks...administrators, and those interested in learning about securing networks a way to conceptualize this complex system of computing. NTAV3D will provide a three...teaching with visual and other components can make learning more effective” (Baxley et al, 2006). A hyperbox (Alpern and Carter, 1991) is

  20. Protein-Protein Interaction Network and Gene Ontology

    NASA Astrophysics Data System (ADS)

    Choi, Yunkyu; Kim, Seok; Yi, Gwan-Su; Park, Jinah

    Evolution of computer technologies makes it possible to access a large amount and various kinds of biological data via internet such as DNA sequences, proteomics data and information discovered about them. It is expected that the combination of various data could help researchers find further knowledge about them. Roles of a visualization system are to invoke human abilities to integrate information and to recognize certain patterns in the data. Thus, when the various kinds of data are examined and analyzed manually, an effective visualization system is an essential part. One instance of these integrated visualizations can be combination of protein-protein interaction (PPI) data and Gene Ontology (GO) which could help enhance the analysis of PPI network. We introduce a simple but comprehensive visualization system that integrates GO and PPI data where GO and PPI graphs are visualized side-by-side and supports quick reference functions between them. Furthermore, the proposed system provides several interactive visualization methods for efficiently analyzing the PPI network and GO directedacyclic- graph such as context-based browsing and common ancestors finding.

  1. Real-time scalable visual analysis on mobile devices

    NASA Astrophysics Data System (ADS)

    Pattath, Avin; Ebert, David S.; May, Richard A.; Collins, Timothy F.; Pike, William

    2008-02-01

    Interactive visual presentation of information can help an analyst gain faster and better insight from data. When combined with situational or context information, visualization on mobile devices is invaluable to in-field responders and investigators. However, several challenges are posed by the form-factor of mobile devices in developing such systems. In this paper, we classify these challenges into two broad categories - issues in general mobile computing and issues specific to visual analysis on mobile devices. Using NetworkVis and Infostar as example systems, we illustrate some of the techniques that we employed to overcome many of the identified challenges. NetworkVis is an OpenVG-based real-time network monitoring and visualization system developed for Windows Mobile devices. Infostar is a flash-based interactive, real-time visualization application intended to provide attendees access to conference information. Linked time-synchronous visualization, stylus/button-based interactivity, vector graphics, overview-context techniques, details-on-demand and statistical information display are some of the highlights of these applications.

  2. A case for spiking neural network simulation based on configurable multiple-FPGA systems.

    PubMed

    Yang, Shufan; Wu, Qiang; Li, Renfa

    2011-09-01

    Recent neuropsychological research has begun to reveal that neurons encode information in the timing of spikes. Spiking neural network simulations are a flexible and powerful method for investigating the behaviour of neuronal systems. Simulation of the spiking neural networks in software is unable to rapidly generate output spikes in large-scale of neural network. An alternative approach, hardware implementation of such system, provides the possibility to generate independent spikes precisely and simultaneously output spike waves in real time, under the premise that spiking neural network can take full advantage of hardware inherent parallelism. We introduce a configurable FPGA-oriented hardware platform for spiking neural network simulation in this work. We aim to use this platform to combine the speed of dedicated hardware with the programmability of software so that it might allow neuroscientists to put together sophisticated computation experiments of their own model. A feed-forward hierarchy network is developed as a case study to describe the operation of biological neural systems (such as orientation selectivity of visual cortex) and computational models of such systems. This model demonstrates how a feed-forward neural network constructs the circuitry required for orientation selectivity and provides platform for reaching a deeper understanding of the primate visual system. In the future, larger scale models based on this framework can be used to replicate the actual architecture in visual cortex, leading to more detailed predictions and insights into visual perception phenomenon.

  3. Intrusion Detection System Visualization of Network Alerts

    DTIC Science & Technology

    2010-07-01

    Intrusion Detection System Visualization of Network Alerts Dolores M. Zage and Wayne M. Zage Ball State University Final Report July 2010...contracts. Staff Wayne Zage, Director of the S2ERC and Professor, Department of Computer Science, Ball State University Dolores Zage, Research

  4. VANLO - Interactive visual exploration of aligned biological networks

    PubMed Central

    Brasch, Steffen; Linsen, Lars; Fuellen, Georg

    2009-01-01

    Background Protein-protein interaction (PPI) is fundamental to many biological processes. In the course of evolution, biological networks such as protein-protein interaction networks have developed. Biological networks of different species can be aligned by finding instances (e.g. proteins) with the same common ancestor in the evolutionary process, so-called orthologs. For a better understanding of the evolution of biological networks, such aligned networks have to be explored. Visualization can play a key role in making the various relationships transparent. Results We present a novel visualization system for aligned biological networks in 3D space that naturally embeds existing 2D layouts. In addition to displaying the intra-network connectivities, we also provide insight into how the individual networks relate to each other by placing aligned entities on top of each other in separate layers. We optimize the layout of the entire alignment graph in a global fashion that takes into account inter- as well as intra-network relationships. The layout algorithm includes a step of merging aligned networks into one graph, laying out the graph with respect to application-specific requirements, splitting the merged graph again into individual networks, and displaying the network alignment in layers. In addition to representing the data in a static way, we also provide different interaction techniques to explore the data with respect to application-specific tasks. Conclusion Our system provides an intuitive global understanding of aligned PPI networks and it allows the investigation of key biological questions. We evaluate our system by applying it to real-world examples documenting how our system can be used to investigate the data with respect to these key questions. Our tool VANLO (Visualization of Aligned Networks with Layout Optimization) can be accessed at . PMID:19821976

  5. Neural network system for purposeful behavior based on foveal visual preprocessor

    NASA Astrophysics Data System (ADS)

    Golovan, Alexander V.; Shevtsova, Natalia A.; Klepatch, Arkadi A.

    1996-10-01

    Biologically plausible model of the system with an adaptive behavior in a priori environment and resistant to impairment has been developed. The system consists of input, learning, and output subsystems. The first subsystems classifies input patterns presented as n-dimensional vectors in accordance with some associative rule. The second one being a neural network determines adaptive responses of the system to input patterns. Arranged neural groups coding possible input patterns and appropriate output responses are formed during learning by means of negative reinforcement. Output subsystem maps a neural network activity into the system behavior in the environment. The system developed has been studied by computer simulation imitating a collision-free motion of a mobile robot. After some learning period the system 'moves' along a road without collisions. It is shown that in spite of impairment of some neural network elements the system functions reliably after relearning. Foveal visual preprocessor model developed earlier has been tested to form a kind of visual input to the system.

  6. Visual Representations of Microcosm in Textbooks of Chemistry: Constructing a Systemic Network for Their Main Conceptual Framework

    ERIC Educational Resources Information Center

    Papageorgiou, George; Amariotakis, Vasilios; Spiliotopoulou, Vasiliki

    2017-01-01

    The main objective of this work is to analyse the visual representations (VRs) of the microcosm depicted in nine Greek secondary chemistry school textbooks of the last three decades in order to construct a systemic network for their main conceptual framework and to evaluate the contribution of each one of the resulting categories to the network.…

  7. Consistent visualizations of changing knowledge

    PubMed Central

    Tipney, Hannah J.; Schuyler, Ronald P.; Hunter, Lawrence

    2009-01-01

    Networks are increasingly used in biology to represent complex data in uncomplicated symbolic form. However, as biological knowledge is continually evolving, so must those networks representing this knowledge. Capturing and presenting this type of knowledge change over time is particularly challenging due to the intimate manner in which researchers customize those networks they come into contact with. The effective visualization of this knowledge is important as it creates insight into complex systems and stimulates hypothesis generation and biological discovery. Here we highlight how the retention of user customizations, and the collection and visualization of knowledge associated provenance supports effective and productive network exploration. We also present an extension of the Hanalyzer system, ReOrient, which supports network exploration and analysis in the presence of knowledge change. PMID:21347184

  8. Alerts Analysis and Visualization in Network-based Intrusion Detection Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yang, Dr. Li

    2010-08-01

    The alerts produced by network-based intrusion detection systems, e.g. Snort, can be difficult for network administrators to efficiently review and respond to due to the enormous number of alerts generated in a short time frame. This work describes how the visualization of raw IDS alert data assists network administrators in understanding the current state of a network and quickens the process of reviewing and responding to intrusion attempts. The project presented in this work consists of three primary components. The first component provides a visual mapping of the network topology that allows the end-user to easily browse clustered alerts. Themore » second component is based on the flocking behavior of birds such that birds tend to follow other birds with similar behaviors. This component allows the end-user to see the clustering process and provides an efficient means for reviewing alert data. The third component discovers and visualizes patterns of multistage attacks by profiling the attacker s behaviors.« less

  9. Efficient encoding of motion is mediated by gap junctions in the fly visual system.

    PubMed

    Wang, Siwei; Borst, Alexander; Zaslavsky, Noga; Tishby, Naftali; Segev, Idan

    2017-12-01

    Understanding the computational implications of specific synaptic connectivity patterns is a fundamental goal in neuroscience. In particular, the computational role of ubiquitous electrical synapses operating via gap junctions remains elusive. In the fly visual system, the cells in the vertical-system network, which play a key role in visual processing, primarily connect to each other via axonal gap junctions. This network therefore provides a unique opportunity to explore the functional role of gap junctions in sensory information processing. Our information theoretical analysis of a realistic VS network model shows that within 10 ms following the onset of the visual input, the presence of axonal gap junctions enables the VS system to efficiently encode the axis of rotation, θ, of the fly's ego motion. This encoding efficiency, measured in bits, is near-optimal with respect to the physical limits of performance determined by the statistical structure of the visual input itself. The VS network is known to be connected to downstream pathways via a subset of triplets of the vertical system cells; we found that because of the axonal gap junctions, the efficiency of this subpopulation in encoding θ is superior to that of the whole vertical system network and is robust to a wide range of signal to noise ratios. We further demonstrate that this efficient encoding of motion by this subpopulation is necessary for the fly's visually guided behavior, such as banked turns in evasive maneuvers. Because gap junctions are formed among the axons of the vertical system cells, they only impact the system's readout, while maintaining the dendritic input intact, suggesting that the computational principles implemented by neural circuitries may be much richer than previously appreciated based on point neuron models. Our study provides new insights as to how specific network connectivity leads to efficient encoding of sensory stimuli.

  10. Promoting Social Network Awareness: A Social Network Monitoring System

    ERIC Educational Resources Information Center

    Cadima, Rita; Ferreira, Carlos; Monguet, Josep; Ojeda, Jordi; Fernandez, Joaquin

    2010-01-01

    To increase communication and collaboration opportunities, members of a community must be aware of the social networks that exist within that community. This paper describes a social network monitoring system--the KIWI system--that enables users to register their interactions and visualize their social networks. The system was implemented in a…

  11. BioCichlid: central dogma-based 3D visualization system of time-course microarray data on a hierarchical biological network.

    PubMed

    Ishiwata, Ryosuke R; Morioka, Masaki S; Ogishima, Soichi; Tanaka, Hiroshi

    2009-02-15

    BioCichlid is a 3D visualization system of time-course microarray data on molecular networks, aiming at interpretation of gene expression data by transcriptional relationships based on the central dogma with physical and genetic interactions. BioCichlid visualizes both physical (protein) and genetic (regulatory) network layers, and provides animation of time-course gene expression data on the genetic network layer. Transcriptional regulations are represented to bridge the physical network (transcription factors) and genetic network (regulated genes) layers, thus integrating promoter analysis into the pathway mapping. BioCichlid enhances the interpretation of microarray data and allows for revealing the underlying mechanisms causing differential gene expressions. BioCichlid is freely available and can be accessed at http://newton.tmd.ac.jp/. Source codes for both biocichlid server and client are also available.

  12. HPIminer: A text mining system for building and visualizing human protein interaction networks and pathways.

    PubMed

    Subramani, Suresh; Kalpana, Raja; Monickaraj, Pankaj Moses; Natarajan, Jeyakumar

    2015-04-01

    The knowledge on protein-protein interactions (PPI) and their related pathways are equally important to understand the biological functions of the living cell. Such information on human proteins is highly desirable to understand the mechanism of several diseases such as cancer, diabetes, and Alzheimer's disease. Because much of that information is buried in biomedical literature, an automated text mining system for visualizing human PPI and pathways is highly desirable. In this paper, we present HPIminer, a text mining system for visualizing human protein interactions and pathways from biomedical literature. HPIminer extracts human PPI information and PPI pairs from biomedical literature, and visualize their associated interactions, networks and pathways using two curated databases HPRD and KEGG. To our knowledge, HPIminer is the first system to build interaction networks from literature as well as curated databases. Further, the new interactions mined only from literature and not reported earlier in databases are highlighted as new. A comparative study with other similar tools shows that the resultant network is more informative and provides additional information on interacting proteins and their associated networks. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Multi-focus and multi-level techniques for visualization and analysis of networks with thematic data

    NASA Astrophysics Data System (ADS)

    Cossalter, Michele; Mengshoel, Ole J.; Selker, Ted

    2013-01-01

    Information-rich data sets bring several challenges in the areas of visualization and analysis, even when associated with node-link network visualizations. This paper presents an integration of multi-focus and multi-level techniques that enable interactive, multi-step comparisons in node-link networks. We describe NetEx, a visualization tool that enables users to simultaneously explore different parts of a network and its thematic data, such as time series or conditional probability tables. NetEx, implemented as a Cytoscape plug-in, has been applied to the analysis of electrical power networks, Bayesian networks, and the Enron e-mail repository. In this paper we briefly discuss visualization and analysis of the Enron social network, but focus on data from an electrical power network. Specifically, we demonstrate how NetEx supports the analytical task of electrical power system fault diagnosis. Results from a user study with 25 subjects suggest that NetEx enables more accurate isolation of complex faults compared to an especially designed software tool.

  14. Level-2 Milestone 4797: Early Users on Max, Sequoia Visualization Cluster

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cupps, Kim C.

    This report documents the fact that an early user has run successfully on Max, the Sequoia visualization cluster, ASC L2 milestone 4797: Early Users on Sequoia Visualization System (Max), due December 31, 2013. The Max visualization and data analysis cluster will provide Sequoia users with compute cycles and an interactive option for data exploration and analysis. The system will be integrated in the first quarter of FY14 and the system is expected to be moved to the classified network by the second quarter of FY14. The goal of this milestone is to have early users running their visualization and datamore » analysis work on the Max cluster on the classified network.« less

  15. Modeling for Visual Feature Extraction Using Spiking Neural Networks

    NASA Astrophysics Data System (ADS)

    Kimura, Ichiro; Kuroe, Yasuaki; Kotera, Hiromichi; Murata, Tomoya

    This paper develops models for “visual feature extraction” in biological systems by using “spiking neural network (SNN)”. The SNN is promising for developing the models because the information is encoded and processed by spike trains similar to biological neural networks. Two architectures of SNN are proposed for modeling the directionally selective and the motion parallax cell in neuro-sensory systems and they are trained so as to possess actual biological responses of each cell. To validate the developed models, their representation ability is investigated and their visual feature extraction mechanisms are discussed from the neurophysiological viewpoint. It is expected that this study can be the first step to developing a sensor system similar to the biological systems and also a complementary approach to investigating the function of the brain.

  16. Visual experience sculpts whole-cortex spontaneous infraslow activity patterns through an Arc-dependent mechanism

    PubMed Central

    Kraft, Andrew W.; Mitra, Anish; Bauer, Adam Q.; Raichle, Marcus E.; Culver, Joseph P.; Lee, Jin-Moo

    2017-01-01

    Decades of work in experimental animals has established the importance of visual experience during critical periods for the development of normal sensory-evoked responses in the visual cortex. However, much less is known concerning the impact of early visual experience on the systems-level organization of spontaneous activity. Human resting-state fMRI has revealed that infraslow fluctuations in spontaneous activity are organized into stereotyped spatiotemporal patterns across the entire brain. Furthermore, the organization of spontaneous infraslow activity (ISA) is plastic in that it can be modulated by learning and experience, suggesting heightened sensitivity to change during critical periods. Here we used wide-field optical intrinsic signal imaging in mice to examine whole-cortex spontaneous ISA patterns. Using monocular or binocular visual deprivation, we examined the effects of critical period visual experience on the development of ISA correlation and latency patterns within and across cortical resting-state networks. Visual modification with monocular lid suturing reduced correlation between left and right cortices (homotopic correlation) within the visual network, but had little effect on internetwork correlation. In contrast, visual deprivation with binocular lid suturing resulted in increased visual homotopic correlation and increased anti-correlation between the visual network and several extravisual networks, suggesting cross-modal plasticity. These network-level changes were markedly attenuated in mice with genetic deletion of Arc, a gene known to be critical for activity-dependent synaptic plasticity. Taken together, our results suggest that critical period visual experience induces global changes in spontaneous ISA relationships, both within the visual network and across networks, through an Arc-dependent mechanism. PMID:29087327

  17. Target recognition and scene interpretation in image/video understanding systems based on network-symbolic models

    NASA Astrophysics Data System (ADS)

    Kuvich, Gary

    2004-08-01

    Vision is only a part of a system that converts visual information into knowledge structures. These structures drive the vision process, resolving ambiguity and uncertainty via feedback, and provide image understanding, which is an interpretation of visual information in terms of these knowledge models. These mechanisms provide a reliable recognition if the object is occluded or cannot be recognized as a whole. It is hard to split the entire system apart, and reliable solutions to the target recognition problems are possible only within the solution of a more generic Image Understanding Problem. Brain reduces informational and computational complexities, using implicit symbolic coding of features, hierarchical compression, and selective processing of visual information. Biologically inspired Network-Symbolic representation, where both systematic structural/logical methods and neural/statistical methods are parts of a single mechanism, is the most feasible for such models. It converts visual information into relational Network-Symbolic structures, avoiding artificial precise computations of 3-dimensional models. Network-Symbolic Transformations derive abstract structures, which allows for invariant recognition of an object as exemplar of a class. Active vision helps creating consistent models. Attention, separation of figure from ground and perceptual grouping are special kinds of network-symbolic transformations. Such Image/Video Understanding Systems will be reliably recognizing targets.

  18. A Markov chain model for image ranking system in social networks

    NASA Astrophysics Data System (ADS)

    Zin, Thi Thi; Tin, Pyke; Toriu, Takashi; Hama, Hiromitsu

    2014-03-01

    In today world, different kinds of networks such as social, technological, business and etc. exist. All of the networks are similar in terms of distributions, continuously growing and expanding in large scale. Among them, many social networks such as Facebook, Twitter, Flickr and many others provides a powerful abstraction of the structure and dynamics of diverse kinds of inter personal connection and interaction. Generally, the social network contents are created and consumed by the influences of all different social navigation paths that lead to the contents. Therefore, identifying important and user relevant refined structures such as visual information or communities become major factors in modern decision making world. Moreover, the traditional method of information ranking systems cannot be successful due to their lack of taking into account the properties of navigation paths driven by social connections. In this paper, we propose a novel image ranking system in social networks by using the social data relational graphs from social media platform jointly with visual data to improve the relevance between returned images and user intentions (i.e., social relevance). Specifically, we propose a Markov chain based Social-Visual Ranking algorithm by taking social relevance into account. By using some extensive experiments, we demonstrated the significant and effectiveness of the proposed social-visual ranking method.

  19. Real-time visual communication to aid disaster recovery in a multi-segment hybrid wireless networking system

    NASA Astrophysics Data System (ADS)

    Al Hadhrami, Tawfik; Wang, Qi; Grecos, Christos

    2012-06-01

    When natural disasters or other large-scale incidents occur, obtaining accurate and timely information on the developing situation is vital to effective disaster recovery operations. High-quality video streams and high-resolution images, if available in real time, would provide an invaluable source of current situation reports to the incident management team. Meanwhile, a disaster often causes significant damage to the communications infrastructure. Therefore, another essential requirement for disaster management is the ability to rapidly deploy a flexible incident area communication network. Such a network would facilitate the transmission of real-time video streams and still images from the disrupted area to remote command and control locations. In this paper, a comprehensive end-to-end video/image transmission system between an incident area and a remote control centre is proposed and implemented, and its performance is experimentally investigated. In this study a hybrid multi-segment communication network is designed that seamlessly integrates terrestrial wireless mesh networks (WMNs), distributed wireless visual sensor networks, an airborne platform with video camera balloons, and a Digital Video Broadcasting- Satellite (DVB-S) system. By carefully integrating all of these rapidly deployable, interworking and collaborative networking technologies, we can fully exploit the joint benefits provided by WMNs, WSNs, balloon camera networks and DVB-S for real-time video streaming and image delivery in emergency situations among the disaster hit area, the remote control centre and the rescue teams in the field. The whole proposed system is implemented in a proven simulator. Through extensive simulations, the real-time visual communication performance of this integrated system has been numerically evaluated, towards a more in-depth understanding in supporting high-quality visual communications in such a demanding context.

  20. What is the optimal architecture for visual information routing?

    PubMed

    Wolfrum, Philipp; von der Malsburg, Christoph

    2007-12-01

    Analyzing the design of networks for visual information routing is an underconstrained problem due to insufficient anatomical and physiological data. We propose here optimality criteria for the design of routing networks. For a very general architecture, we derive the number of routing layers and the fanout that minimize the required neural circuitry. The optimal fanout l is independent of network size, while the number k of layers scales logarithmically (with a prefactor below 1), with the number n of visual resolution units to be routed independently. The results are found to agree with data of the primate visual system.

  1. CyberPetri at CDX 2016: Real-time Network Situation Awareness

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Arendt, Dustin L.; Best, Daniel M.; Burtner, Edwin R.

    CyberPetri is a novel visualization technique that provides a flexible map of the network based on available characteristics, such as IP address, operating system, or service. Previous work introduced CyberPetri as a visualization feature in Ocelot, a network defense tool that helped security analysts understand and respond to an active defense scenario. In this paper we present a case study in which we use the CyberPetri visualization technique to support real-time situation awareness during the 2016 Cyber Defense Exercise.

  2. Brain functional network connectivity based on a visual task: visual information processing-related brain regions are significantly activated in the task state.

    PubMed

    Yang, Yan-Li; Deng, Hong-Xia; Xing, Gui-Yang; Xia, Xiao-Luan; Li, Hai-Fang

    2015-02-01

    It is not clear whether the method used in functional brain-network related research can be applied to explore the feature binding mechanism of visual perception. In this study, we investigated feature binding of color and shape in visual perception. Functional magnetic resonance imaging data were collected from 38 healthy volunteers at rest and while performing a visual perception task to construct brain networks active during resting and task states. Results showed that brain regions involved in visual information processing were obviously activated during the task. The components were partitioned using a greedy algorithm, indicating the visual network existed during the resting state. Z-values in the vision-related brain regions were calculated, confirming the dynamic balance of the brain network. Connectivity between brain regions was determined, and the result showed that occipital and lingual gyri were stable brain regions in the visual system network, the parietal lobe played a very important role in the binding process of color features and shape features, and the fusiform and inferior temporal gyri were crucial for processing color and shape information. Experimental findings indicate that understanding visual feature binding and cognitive processes will help establish computational models of vision, improve image recognition technology, and provide a new theoretical mechanism for feature binding in visual perception.

  3. Review: visual analytics of climate networks

    NASA Astrophysics Data System (ADS)

    Nocke, T.; Buschmann, S.; Donges, J. F.; Marwan, N.; Schulz, H.-J.; Tominski, C.

    2015-09-01

    Network analysis has become an important approach in studying complex spatiotemporal behaviour within geophysical observation and simulation data. This new field produces increasing numbers of large geo-referenced networks to be analysed. Particular focus lies currently on the network analysis of the complex statistical interrelationship structure within climatological fields. The standard procedure for such network analyses is the extraction of network measures in combination with static standard visualisation methods. Existing interactive visualisation methods and tools for geo-referenced network exploration are often either not known to the analyst or their potential is not fully exploited. To fill this gap, we illustrate how interactive visual analytics methods in combination with geovisualisation can be tailored for visual climate network investigation. Therefore, the paper provides a problem analysis relating the multiple visualisation challenges to a survey undertaken with network analysts from the research fields of climate and complex systems science. Then, as an overview for the interested practitioner, we review the state-of-the-art in climate network visualisation and provide an overview of existing tools. As a further contribution, we introduce the visual network analytics tools CGV and GTX, providing tailored solutions for climate network analysis, including alternative geographic projections, edge bundling, and 3-D network support. Using these tools, the paper illustrates the application potentials of visual analytics for climate networks based on several use cases including examples from global, regional, and multi-layered climate networks.

  4. Review: visual analytics of climate networks

    NASA Astrophysics Data System (ADS)

    Nocke, T.; Buschmann, S.; Donges, J. F.; Marwan, N.; Schulz, H.-J.; Tominski, C.

    2015-04-01

    Network analysis has become an important approach in studying complex spatiotemporal behaviour within geophysical observation and simulation data. This new field produces increasing amounts of large geo-referenced networks to be analysed. Particular focus lies currently on the network analysis of the complex statistical interrelationship structure within climatological fields. The standard procedure for such network analyses is the extraction of network measures in combination with static standard visualisation methods. Existing interactive visualisation methods and tools for geo-referenced network exploration are often either not known to the analyst or their potential is not fully exploited. To fill this gap, we illustrate how interactive visual analytics methods in combination with geovisualisation can be tailored for visual climate network investigation. Therefore, the paper provides a problem analysis, relating the multiple visualisation challenges with a survey undertaken with network analysts from the research fields of climate and complex systems science. Then, as an overview for the interested practitioner, we review the state-of-the-art in climate network visualisation and provide an overview of existing tools. As a further contribution, we introduce the visual network analytics tools CGV and GTX, providing tailored solutions for climate network analysis, including alternative geographic projections, edge bundling, and 3-D network support. Using these tools, the paper illustrates the application potentials of visual analytics for climate networks based on several use cases including examples from global, regional, and multi-layered climate networks.

  5. BiNA: A Visual Analytics Tool for Biological Network Data

    PubMed Central

    Gerasch, Andreas; Faber, Daniel; Küntzer, Jan; Niermann, Peter; Kohlbacher, Oliver; Lenhof, Hans-Peter; Kaufmann, Michael

    2014-01-01

    Interactive visual analysis of biological high-throughput data in the context of the underlying networks is an essential task in modern biomedicine with applications ranging from metabolic engineering to personalized medicine. The complexity and heterogeneity of data sets require flexible software architectures for data analysis. Concise and easily readable graphical representation of data and interactive navigation of large data sets are essential in this context. We present BiNA - the Biological Network Analyzer - a flexible open-source software for analyzing and visualizing biological networks. Highly configurable visualization styles for regulatory and metabolic network data offer sophisticated drawings and intuitive navigation and exploration techniques using hierarchical graph concepts. The generic projection and analysis framework provides powerful functionalities for visual analyses of high-throughput omics data in the context of networks, in particular for the differential analysis and the analysis of time series data. A direct interface to an underlying data warehouse provides fast access to a wide range of semantically integrated biological network databases. A plugin system allows simple customization and integration of new analysis algorithms or visual representations. BiNA is available under the 3-clause BSD license at http://bina.unipax.info/. PMID:24551056

  6. Processing Of Visual Information In Primate Brains

    NASA Technical Reports Server (NTRS)

    Anderson, Charles H.; Van Essen, David C.

    1991-01-01

    Report reviews and analyzes information-processing strategies and pathways in primate retina and visual cortex. Of interest both in biological fields and in such related computational fields as artificial neural networks. Focuses on data from macaque, which has superb visual system similar to that of humans. Authors stress concept of "good engineering" in understanding visual system.

  7. Construction of Blaze at the University of Illinois at Chicago: A Shared, High-Performance, Visual Computer for Next-Generation Cyberinfrastructure-Accelerated Scientific, Engineering, Medical and Public Policy Research

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brown, Maxine D.; Leigh, Jason

    2014-02-17

    The Blaze high-performance visual computing system serves the high-performance computing research and education needs of University of Illinois at Chicago (UIC). Blaze consists of a state-of-the-art, networked, computer cluster and ultra-high-resolution visualization system called CAVE2(TM) that is currently not available anywhere in Illinois. This system is connected via a high-speed 100-Gigabit network to the State of Illinois' I-WIRE optical network, as well as to national and international high speed networks, such as the Internet2, and the Global Lambda Integrated Facility. This enables Blaze to serve as an on-ramp to national cyberinfrastructure, such as the National Science Foundation’s Blue Waters petascalemore » computer at the National Center for Supercomputing Applications at the University of Illinois at Chicago and the Department of Energy’s Argonne Leadership Computing Facility (ALCF) at Argonne National Laboratory. DOE award # DE-SC005067, leveraged with NSF award #CNS-0959053 for “Development of the Next-Generation CAVE Virtual Environment (NG-CAVE),” enabled us to create a first-of-its-kind high-performance visual computing system. The UIC Electronic Visualization Laboratory (EVL) worked with two U.S. companies to advance their commercial products and maintain U.S. leadership in the global information technology economy. New applications are being enabled with the CAVE2/Blaze visual computing system that is advancing scientific research and education in the U.S. and globally, and help train the next-generation workforce.« less

  8. Secure videoconferencing equipment switching system and method

    DOEpatents

    Hansen, Michael E [Livermore, CA

    2009-01-13

    A switching system and method are provided to facilitate use of videoconference facilities over a plurality of security levels. The system includes a switch coupled to a plurality of codecs and communication networks. Audio/Visual peripheral components are connected to the switch. The switch couples control and data signals between the Audio/Visual peripheral components and one but nor both of the plurality of codecs. The switch additionally couples communication networks of the appropriate security level to each of the codecs. In this manner, a videoconferencing facility is provided for use on both secure and non-secure networks.

  9. Neural attractor network for application in visual field data classification.

    PubMed

    Fink, Wolfgang

    2004-07-07

    The purpose was to introduce a novel method for computer-based classification of visual field data derived from perimetric examination, that may act as a 'counsellor', providing an independent 'second opinion' to the diagnosing physician. The classification system consists of a Hopfield-type neural attractor network that obtains its input data from perimetric examination results. An iterative relaxation process determines the states of the neurons dynamically. Therefore, even 'noisy' perimetric output, e.g., early stages of a disease, may eventually be classified correctly according to the predefined idealized visual field defect (scotoma) patterns, stored as attractors of the network, that are found with diseases of the eye, optic nerve and the central nervous system. Preliminary tests of the classification system on real visual field data derived from perimetric examinations have shown a classification success of over 80%. Some of the main advantages of the Hopfield-attractor-network-based approach over feed-forward type neural networks are: (1) network architecture is defined by the classification problem; (2) no training is required to determine the neural coupling strengths; (3) assignment of an auto-diagnosis confidence level is possible by means of an overlap parameter and the Hamming distance. In conclusion, the novel method for computer-based classification of visual field data, presented here, furnishes a valuable first overview and an independent 'second opinion' in judging perimetric examination results, pointing towards a final diagnosis by a physician. It should not be considered a substitute for the diagnosing physician. Thanks to the worldwide accessibility of the Internet, the classification system offers a promising perspective towards modern computer-assisted diagnosis in both medicine and tele-medicine, for example and in particular, with respect to non-ophthalmic clinics or in communities where perimetric expertise is not readily available.

  10. Networks for image acquisition, processing and display

    NASA Technical Reports Server (NTRS)

    Ahumada, Albert J., Jr.

    1990-01-01

    The human visual system comprises layers of networks which sample, process, and code images. Understanding these networks is a valuable means of understanding human vision and of designing autonomous vision systems based on network processing. Ames Research Center has an ongoing program to develop computational models of such networks. The models predict human performance in detection of targets and in discrimination of displayed information. In addition, the models are artificial vision systems sharing properties with biological vision that has been tuned by evolution for high performance. Properties include variable density sampling, noise immunity, multi-resolution coding, and fault-tolerance. The research stresses analysis of noise in visual networks, including sampling, photon, and processing unit noises. Specific accomplishments include: models of sampling array growth with variable density and irregularity comparable to that of the retinal cone mosaic; noise models of networks with signal-dependent and independent noise; models of network connection development for preserving spatial registration and interpolation; multi-resolution encoding models based on hexagonal arrays (HOP transform); and mathematical procedures for simplifying analysis of large networks.

  11. The Curriculum Prerequisite Network: Modeling the Curriculum as a Complex System

    ERIC Educational Resources Information Center

    Aldrich, Preston R.

    2015-01-01

    This article advances the prerequisite network as a means to visualize the hidden structure in an academic curriculum. Networks have been used to represent a variety of complex systems ranging from social systems to biochemical pathways and protein interactions. Here, I treat the academic curriculum as a complex system with nodes representing…

  12. Visual Network Asymmetry and Default Mode Network Function in ADHD: An fMRI Study

    PubMed Central

    Hale, T. Sigi; Kane, Andrea M.; Kaminsky, Olivia; Tung, Kelly L.; Wiley, Joshua F.; McGough, James J.; Loo, Sandra K.; Kaplan, Jonas T.

    2014-01-01

    Background: A growing body of research has identified abnormal visual information processing in attention-deficit hyperactivity disorder (ADHD). In particular, slow processing speed and increased reliance on visuo-perceptual strategies have become evident. Objective: The current study used recently developed fMRI methods to replicate and further examine abnormal rightward biased visual information processing in ADHD and to further characterize the nature of this effect; we tested its association with several large-scale distributed network systems. Method: We examined fMRI BOLD response during letter and location judgment tasks, and directly assessed visual network asymmetry and its association with large-scale networks using both a voxelwise and an averaged signal approach. Results: Initial within-group analyses revealed a pattern of left-lateralized visual cortical activity in controls but right-lateralized visual cortical activity in ADHD children. Direct analyses of visual network asymmetry confirmed atypical rightward bias in ADHD children compared to controls. This ADHD characteristic was atypically associated with reduced activation across several extra-visual networks, including the default mode network (DMN). We also found atypical associations between DMN activation and ADHD subjects’ inattentive symptoms and task performance. Conclusion: The current study demonstrated rightward VNA in ADHD during a simple letter discrimination task. This result adds an important novel consideration to the growing literature identifying abnormal visual processing in ADHD. We postulate that this characteristic reflects greater perceptual engagement of task-extraneous content, and that it may be a basic feature of less efficient top-down task-directed control over visual processing. We additionally argue that abnormal DMN function may contribute to this characteristic. PMID:25076915

  13. Bandwidth Optimization On Design Of Visual Display Information System Based Networking At Politeknik Negeri Bali

    NASA Astrophysics Data System (ADS)

    Sudiartha, IKG; Catur Bawa, IGNB

    2018-01-01

    Information can not be separated from the social life of the community, especially in the world of education. One of the information fields is academic calendar information, activity agenda, announcement and campus activity news. In line with technological developments, text-based information is becoming obsolete. For that need creativity to present information more quickly, accurately and interesting by exploiting the development of digital technology and internet. In this paper will be developed applications for the provision of information in the form of visual display, applied to computer network system with multimedia applications. Network-based applications provide ease in updating data through internet services, attractive presentations with multimedia support. The application “Networking Visual Display Information Unit” can be used as a medium that provides information services for students and academic employee more interesting and ease in updating information than the bulletin board. The information presented in the form of Running Text, Latest Information, Agenda, Academic Calendar and Video provide an interesting presentation and in line with technological developments at the Politeknik Negeri Bali. Through this research is expected to create software “Networking Visual Display Information Unit” with optimal bandwidth usage by combining local data sources and data through the network. This research produces visual display design with optimal bandwidth usage and application in the form of supporting software.

  14. Human Mobility Monitoring in Very Low Resolution Visual Sensor Network

    PubMed Central

    Bo Bo, Nyan; Deboeverie, Francis; Eldib, Mohamed; Guan, Junzhi; Xie, Xingzhe; Niño, Jorge; Van Haerenborgh, Dirk; Slembrouck, Maarten; Van de Velde, Samuel; Steendam, Heidi; Veelaert, Peter; Kleihorst, Richard; Aghajan, Hamid; Philips, Wilfried

    2014-01-01

    This paper proposes an automated system for monitoring mobility patterns using a network of very low resolution visual sensors (30 × 30 pixels). The use of very low resolution sensors reduces privacy concern, cost, computation requirement and power consumption. The core of our proposed system is a robust people tracker that uses low resolution videos provided by the visual sensor network. The distributed processing architecture of our tracking system allows all image processing tasks to be done on the digital signal controller in each visual sensor. In this paper, we experimentally show that reliable tracking of people is possible using very low resolution imagery. We also compare the performance of our tracker against a state-of-the-art tracking method and show that our method outperforms. Moreover, the mobility statistics of tracks such as total distance traveled and average speed derived from trajectories are compared with those derived from ground truth given by Ultra-Wide Band sensors. The results of this comparison show that the trajectories from our system are accurate enough to obtain useful mobility statistics. PMID:25375754

  15. Visualizing weighted networks: a performance comparison of adjacency matrices versus node-link diagrams

    NASA Astrophysics Data System (ADS)

    McIntire, John P.; Osesina, O. Isaac; Bartley, Cecilia; Tudoreanu, M. Eduard; Havig, Paul R.; Geiselman, Eric E.

    2012-06-01

    Ensuring the proper and effective ways to visualize network data is important for many areas of academia, applied sciences, the military, and the public. Fields such as social network analysis, genetics, biochemistry, intelligence, cybersecurity, neural network modeling, transit systems, communications, etc. often deal with large, complex network datasets that can be difficult to interact with, study, and use. There have been surprisingly few human factors performance studies on the relative effectiveness of different graph drawings or network diagram techniques to convey information to a viewer. This is particularly true for weighted networks which include the strength of connections between nodes, not just information about which nodes are linked to other nodes. We describe a human factors study in which participants performed four separate network analysis tasks (finding a direct link between given nodes, finding an interconnected node between given nodes, estimating link strengths, and estimating the most densely interconnected nodes) on two different network visualizations: an adjacency matrix with a heat-map versus a node-link diagram. The results should help shed light on effective methods of visualizing network data for some representative analysis tasks, with the ultimate goal of improving usability and performance for viewers of network data displays.

  16. eLoom and Flatland: specification, simulation and visualization engines for the study of arbitrary hierarchical neural architectures.

    PubMed

    Caudell, Thomas P; Xiao, Yunhai; Healy, Michael J

    2003-01-01

    eLoom is an open source graph simulation software tool, developed at the University of New Mexico (UNM), that enables users to specify and simulate neural network models. Its specification language and libraries enables users to construct and simulate arbitrary, potentially hierarchical network structures on serial and parallel processing systems. In addition, eLoom is integrated with UNM's Flatland, an open source virtual environments development tool to provide real-time visualizations of the network structure and activity. Visualization is a useful method for understanding both learning and computation in artificial neural networks. Through 3D animated pictorially representations of the state and flow of information in the network, a better understanding of network functionality is achieved. ART-1, LAPART-II, MLP, and SOM neural networks are presented to illustrate eLoom and Flatland's capabilities.

  17. Developing Visualization Techniques for Semantics-based Information Networks

    NASA Technical Reports Server (NTRS)

    Keller, Richard M.; Hall, David R.

    2003-01-01

    Information systems incorporating complex network structured information spaces with a semantic underpinning - such as hypermedia networks, semantic networks, topic maps, and concept maps - are being deployed to solve some of NASA s critical information management problems. This paper describes some of the human interaction and navigation problems associated with complex semantic information spaces and describes a set of new visual interface approaches to address these problems. A key strategy is to leverage semantic knowledge represented within these information spaces to construct abstractions and views that will be meaningful to the human user. Human-computer interaction methodologies will guide the development and evaluation of these approaches, which will benefit deployed NASA systems and also apply to information systems based on the emerging Semantic Web.

  18. A multilevel layout algorithm for visualizing physical and genetic interaction networks, with emphasis on their modular organization.

    PubMed

    Tuikkala, Johannes; Vähämaa, Heidi; Salmela, Pekka; Nevalainen, Olli S; Aittokallio, Tero

    2012-03-26

    Graph drawing is an integral part of many systems biology studies, enabling visual exploration and mining of large-scale biological networks. While a number of layout algorithms are available in popular network analysis platforms, such as Cytoscape, it remains poorly understood how well their solutions reflect the underlying biological processes that give rise to the network connectivity structure. Moreover, visualizations obtained using conventional layout algorithms, such as those based on the force-directed drawing approach, may become uninformative when applied to larger networks with dense or clustered connectivity structure. We implemented a modified layout plug-in, named Multilevel Layout, which applies the conventional layout algorithms within a multilevel optimization framework to better capture the hierarchical modularity of many biological networks. Using a wide variety of real life biological networks, we carried out a systematic evaluation of the method in comparison with other layout algorithms in Cytoscape. The multilevel approach provided both biologically relevant and visually pleasant layout solutions in most network types, hence complementing the layout options available in Cytoscape. In particular, it could improve drawing of large-scale networks of yeast genetic interactions and human physical interactions. In more general terms, the biological evaluation framework developed here enables one to assess the layout solutions from any existing or future graph drawing algorithm as well as to optimize their performance for a given network type or structure. By making use of the multilevel modular organization when visualizing biological networks, together with the biological evaluation of the layout solutions, one can generate convenient visualizations for many network biology applications.

  19. iCAVE: an open source tool for visualizing biomolecular networks in 3D, stereoscopic 3D and immersive 3D

    PubMed Central

    Liluashvili, Vaja; Kalayci, Selim; Fluder, Eugene; Wilson, Manda; Gabow, Aaron

    2017-01-01

    Abstract Visualizations of biomolecular networks assist in systems-level data exploration in many cellular processes. Data generated from high-throughput experiments increasingly inform these networks, yet current tools do not adequately scale with concomitant increase in their size and complexity. We present an open source software platform, interactome-CAVE (iCAVE), for visualizing large and complex biomolecular interaction networks in 3D. Users can explore networks (i) in 3D using a desktop, (ii) in stereoscopic 3D using 3D-vision glasses and a desktop, or (iii) in immersive 3D within a CAVE environment. iCAVE introduces 3D extensions of known 2D network layout, clustering, and edge-bundling algorithms, as well as new 3D network layout algorithms. Furthermore, users can simultaneously query several built-in databases within iCAVE for network generation or visualize their own networks (e.g., disease, drug, protein, metabolite). iCAVE has modular structure that allows rapid development by addition of algorithms, datasets, or features without affecting other parts of the code. Overall, iCAVE is the first freely available open source tool that enables 3D (optionally stereoscopic or immersive) visualizations of complex, dense, or multi-layered biomolecular networks. While primarily designed for researchers utilizing biomolecular networks, iCAVE can assist researchers in any field. PMID:28814063

  20. iCAVE: an open source tool for visualizing biomolecular networks in 3D, stereoscopic 3D and immersive 3D.

    PubMed

    Liluashvili, Vaja; Kalayci, Selim; Fluder, Eugene; Wilson, Manda; Gabow, Aaron; Gümüs, Zeynep H

    2017-08-01

    Visualizations of biomolecular networks assist in systems-level data exploration in many cellular processes. Data generated from high-throughput experiments increasingly inform these networks, yet current tools do not adequately scale with concomitant increase in their size and complexity. We present an open source software platform, interactome-CAVE (iCAVE), for visualizing large and complex biomolecular interaction networks in 3D. Users can explore networks (i) in 3D using a desktop, (ii) in stereoscopic 3D using 3D-vision glasses and a desktop, or (iii) in immersive 3D within a CAVE environment. iCAVE introduces 3D extensions of known 2D network layout, clustering, and edge-bundling algorithms, as well as new 3D network layout algorithms. Furthermore, users can simultaneously query several built-in databases within iCAVE for network generation or visualize their own networks (e.g., disease, drug, protein, metabolite). iCAVE has modular structure that allows rapid development by addition of algorithms, datasets, or features without affecting other parts of the code. Overall, iCAVE is the first freely available open source tool that enables 3D (optionally stereoscopic or immersive) visualizations of complex, dense, or multi-layered biomolecular networks. While primarily designed for researchers utilizing biomolecular networks, iCAVE can assist researchers in any field. © The Authors 2017. Published by Oxford University Press.

  1. On detection and visualization techniques for cyber security situation awareness

    NASA Astrophysics Data System (ADS)

    Yu, Wei; Wei, Shixiao; Shen, Dan; Blowers, Misty; Blasch, Erik P.; Pham, Khanh D.; Chen, Genshe; Zhang, Hanlin; Lu, Chao

    2013-05-01

    Networking technologies are exponentially increasing to meet worldwide communication requirements. The rapid growth of network technologies and perversity of communications pose serious security issues. In this paper, we aim to developing an integrated network defense system with situation awareness capabilities to present the useful information for human analysts. In particular, we implement a prototypical system that includes both the distributed passive and active network sensors and traffic visualization features, such as 1D, 2D and 3D based network traffic displays. To effectively detect attacks, we also implement algorithms to transform real-world data of IP addresses into images and study the pattern of attacks and use both the discrete wavelet transform (DWT) based scheme and the statistical based scheme to detect attacks. Through an extensive simulation study, our data validate the effectiveness of our implemented defense system.

  2. Common and distinct brain networks underlying verbal and visual creativity.

    PubMed

    Zhu, Wenfeng; Chen, Qunlin; Xia, Lingxiang; Beaty, Roger E; Yang, Wenjing; Tian, Fang; Sun, Jiangzhou; Cao, Guikang; Zhang, Qinglin; Chen, Xu; Qiu, Jiang

    2017-04-01

    Creativity is imperative to the progression of human civilization, prosperity, and well-being. Past creative researches tends to emphasize the default mode network (DMN) or the frontoparietal network (FPN) somewhat exclusively. However, little is known about how these networks interact to contribute to creativity and whether common or distinct brain networks are responsible for visual and verbal creativity. Here, we use functional connectivity analysis of resting-state functional magnetic resonance imaging data to investigate visual and verbal creativity-related regions and networks in 282 healthy subjects. We found that functional connectivity within the bilateral superior parietal cortex of the FPN was negatively associated with visual and verbal creativity. The strength of connectivity between the DMN and FPN was positively related to both creative domains. Visual creativity was negatively correlated with functional connectivity within the precuneus of the pDMN and right middle frontal gyrus of the FPN, and verbal creativity was negatively correlated with functional connectivity within the medial prefrontal cortex of the aDMN. Critically, the FPN mediated the relationship between the aDMN and verbal creativity, and it also mediated the relationship between the pDMN and visual creativity. Taken together, decreased within-network connectivity of the FPN and DMN may allow for flexible between-network coupling in the highly creative brain. These findings provide indirect evidence for the cooperative role of the default and executive control networks in creativity, extending past research by revealing common and distinct brain systems underlying verbal and visual creative cognition. Hum Brain Mapp 38:2094-2111, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  3. Image/video understanding systems based on network-symbolic models

    NASA Astrophysics Data System (ADS)

    Kuvich, Gary

    2004-03-01

    Vision is a part of a larger information system that converts visual information into knowledge structures. These structures drive vision process, resolve ambiguity and uncertainty via feedback projections, and provide image understanding that is an interpretation of visual information in terms of such knowledge models. Computer simulation models are built on the basis of graphs/networks. The ability of human brain to emulate similar graph/network models is found. Symbols, predicates and grammars naturally emerge in such networks, and logic is simply a way of restructuring such models. Brain analyzes an image as a graph-type relational structure created via multilevel hierarchical compression of visual information. Primary areas provide active fusion of image features on a spatial grid-like structure, where nodes are cortical columns. Spatial logic and topology naturally present in such structures. Mid-level vision processes like perceptual grouping, separation of figure from ground, are special kinds of network transformations. They convert primary image structure into the set of more abstract ones, which represent objects and visual scene, making them easy for analysis by higher-level knowledge structures. Higher-level vision phenomena are results of such analysis. Composition of network-symbolic models combines learning, classification, and analogy together with higher-level model-based reasoning into a single framework, and it works similar to frames and agents. Computational intelligence methods transform images into model-based knowledge representation. Based on such principles, an Image/Video Understanding system can convert images into the knowledge models, and resolve uncertainty and ambiguity. This allows creating intelligent computer vision systems for design and manufacturing.

  4. Analysis and Visualization of Relations in eLearning

    NASA Astrophysics Data System (ADS)

    Dráždilová, Pavla; Obadi, Gamila; Slaninová, Kateřina; Martinovič, Jan; Snášel, Václav

    The popularity of eLearning systems is growing rapidly; this growth is enabled by the consecutive development in Internet and multimedia technologies. Web-based education became wide spread in the past few years. Various types of learning management systems facilitate development of Web-based courses. Users of these courses form social networks through the different activities performed by them. This chapter focuses on searching the latent social networks in eLearning systems data. These data consist of students activity records wherein latent ties among actors are embedded. The social network studied in this chapter is represented by groups of students who have similar contacts and interact in similar social circles. Different methods of data clustering analysis can be applied to these groups, and the findings show the existence of latent ties among the group members. The second part of this chapter focuses on social network visualization. Graphical representation of social network can describe its structure very efficiently. It can enable social network analysts to determine the network degree of connectivity. Analysts can easily determine individuals with a small or large amount of relationships as well as the amount of independent groups in a given network. When applied to the field of eLearning, data visualization simplifies the process of monitoring the study activities of individuals or groups, as well as the planning of educational curriculum, the evaluation of study processes, etc.

  5. Active vision and image/video understanding with decision structures based on the network-symbolic models

    NASA Astrophysics Data System (ADS)

    Kuvich, Gary

    2003-08-01

    Vision is a part of a larger information system that converts visual information into knowledge structures. These structures drive vision process, resolve ambiguity and uncertainty via feedback projections, and provide image understanding that is an interpretation of visual information in terms of such knowledge models. The ability of human brain to emulate knowledge structures in the form of networks-symbolic models is found. And that means an important shift of paradigm in our knowledge about brain from neural networks to "cortical software". Symbols, predicates and grammars naturally emerge in such active multilevel hierarchical networks, and logic is simply a way of restructuring such models. Brain analyzes an image as a graph-type decision structure created via multilevel hierarchical compression of visual information. Mid-level vision processes like clustering, perceptual grouping, separation of figure from ground, are special kinds of graph/network transformations. They convert low-level image structure into the set of more abstract ones, which represent objects and visual scene, making them easy for analysis by higher-level knowledge structures. Higher-level vision phenomena are results of such analysis. Composition of network-symbolic models works similar to frames and agents, combines learning, classification, analogy together with higher-level model-based reasoning into a single framework. Such models do not require supercomputers. Based on such principles, and using methods of Computational intelligence, an Image Understanding system can convert images into the network-symbolic knowledge models, and effectively resolve uncertainty and ambiguity, providing unifying representation for perception and cognition. That allows creating new intelligent computer vision systems for robotic and defense industries.

  6. NOAA's Science On a Sphere Education Program: Application of a Scientific Visualization System to Teach Earth System Science and Improve our Understanding About Creating Effective Visualizations

    NASA Astrophysics Data System (ADS)

    McDougall, C.; McLaughlin, J.

    2008-12-01

    NOAA has developed several programs aimed at facilitating the use of earth system science data and data visualizations by formal and informal educators. One of them, Science On a Sphere, a visualization display tool and system that uses networked LCD projectors to display animated global datasets onto the outside of a suspended, 1.7-meter diameter opaque sphere, enables science centers, museums, and universities to display real-time and current earth system science data. NOAA's Office of Education has provided grants to such education institutions to develop exhibits featuring Science On a Sphere (SOS) and create content for and evaluate audience impact. Currently, 20 public education institutions have permanent Science On a Sphere exhibits and 6 more will be installed soon. These institutions and others that are working to create and evaluate content for this system work collaboratively as a network to improve our collective knowledge about how to create educationally effective visualizations. Network members include other federal agencies, such as, NASA and the Dept. of Energy, and major museums such as Smithsonian and American Museum of Natural History, as well as a variety of mid-sized and small museums and universities. Although the audiences in these institutions vary widely in their scientific awareness and understanding, we find there are misconceptions and lack of familiarity with viewing visualizations that are common among the audiences. Through evaluations performed in these institutions we continue to evolve our understanding of how to create content that is understandable by those with minimal scientific literacy. The findings from our network will be presented including the importance of providing context, real-world connections and imagery to accompany the visualizations and the need for audience orientation before the visualizations are viewed. Additionally, we will review the publicly accessible virtual library housing over 200 datasets for SOS and any other real or virtual globe. These datasets represent contributions from NOAA, NASA, Dept. of Energy, and the public institutions that are displaying the spheres.

  7. A Collaborative Education Network for Advancing Climate Literacy using Data Visualization Technology

    NASA Astrophysics Data System (ADS)

    McDougall, C.; Russell, E. L.; Murray, M.; Bendel, W. B.

    2013-12-01

    One of the more difficult issues in engaging broad audiences with scientific research is to present it in a way that is intuitive, captivating and up-to-date. Over the past ten years, the National Oceanic and Atmospheric Administration (NOAA) has made significant progress in this area through Science On a Sphere(R) (SOS). SOS is a room-sized, global display system that uses computers and video projectors to display Earth systems data onto a six-foot diameter sphere, analogous to a giant animated globe. This well-crafted data visualization system serves as a way to integrate and display global change phenomena; including polar ice melt, projected sea level rise, ocean acidification and global climate models. Beyond a display for individual data sets, SOS provides a holistic global perspective that highlights the interconnectedness of Earth systems, nations and communities. SOS is now a featured exhibit at more than 100 science centers, museums, universities, aquariums and other institutions around the world reaching more than 33 million visitors every year. To facilitate the development of how this data visualization technology and these visualizations could be used with public audiences, we recognized the need for the exchange of information among the users. To accomplish this, we established the SOS Users Collaborative Network. This network consists of the institutions that have an SOS system or partners who are creating content and educational programming for SOS. When we began the Network in 2005, many museums had limited capacity to both incorporate real-time, authentic scientific data about the Earth system and interpret global change visualizations. They needed not only the visualization platform and the scientific content, but also assistance with methods of approach. We needed feedback from these users on how to craft understandable visualizations and how to further develop the SOS platform to support learning. Through this Network and the collaboration among members, we have, collectively, been able to advance all of our efforts. The member institutions, through regular face-to-face workshops and an online community, share practices in creation and cataloging of datasets, new methods for delivering content via SOS, and updates on the SOS system and software. One hallmark of the SOS Users Collaborative Network is that it exemplifies an ideal partnership between federal science agencies and informal science education institutions. The science agencies (including NOAA, NASA, and the Department of Energy) provide continuously updated global datasets, scientific expertise, funding, and support. In turn, museums act as trusted public providers of scientific information, provide audience-appropriate presentations, localized relevance to global phenomena and a forum for discussing the complex science and repercussions of global change. We will discuss the characteristics of this Network that maximize collaboration and what we're learning as a community to improve climate literacy.

  8. Identifying and tracking attacks on networks: C3I displays and related technologies

    NASA Astrophysics Data System (ADS)

    Manes, Gavin W.; Dawkins, J.; Shenoi, Sujeet; Hale, John C.

    2003-09-01

    Converged network security is extremely challenging for several reasons; expanded system and technology perimeters, unexpected feature interaction, and complex interfaces all conspire to provide hackers with greater opportunities for compromising large networks. Preventive security services and architectures are essential, but in and of themselves do not eliminate all threat of compromise. Attack management systems mitigate this residual risk by facilitating incident detection, analysis and response. There are a wealth of attack detection and response tools for IP networks, but a dearth of such tools for wireless and public telephone networks. Moreover, methodologies and formalisms have yet to be identified that can yield a common model for vulnerabilities and attacks in converged networks. A comprehensive attack management system must coordinate detection tools for converged networks, derive fully-integrated attack and network models, perform vulnerability and multi-stage attack analysis, support large-scale attack visualization, and orchestrate strategic responses to cyber attacks that cross network boundaries. We present an architecture that embodies these principles for attack management. The attack management system described engages a suite of detection tools for various networking domains, feeding real-time attack data to a comprehensive modeling, analysis and visualization subsystem. The resulting early warning system not only provides network administrators with a heads-up cockpit display of their entire network, it also supports guided response and predictive capabilities for multi-stage attacks in converged networks.

  9. SocialMood: an information visualization tool to measure the mood of the people in social networks

    NASA Astrophysics Data System (ADS)

    Amorim, Guilherme; Franco, Roberto; Moraes, Rodolfo; Figueiredo, Bruno; Miranda, João.; Dobrões, José; Afonso, Ricardo; Meiguins, Bianchi

    2013-12-01

    Based on the arena of social networks, the tool developed in this study aims to identify trends mood among undergraduate students. Combining the methodology Self-Assessment Manikin (SAM), which originated in the field of Psychology, the system filters the content provided on the Web and isolates certain words, establishing a range of values as perceived positive, negative or neutral. A Big Data summarizing the results, assisting in the construction and visualization of behavioral profiles generic, so we have a guideline for the development of information visualization tools for social networks.

  10. A multilevel layout algorithm for visualizing physical and genetic interaction networks, with emphasis on their modular organization

    PubMed Central

    2012-01-01

    Background Graph drawing is an integral part of many systems biology studies, enabling visual exploration and mining of large-scale biological networks. While a number of layout algorithms are available in popular network analysis platforms, such as Cytoscape, it remains poorly understood how well their solutions reflect the underlying biological processes that give rise to the network connectivity structure. Moreover, visualizations obtained using conventional layout algorithms, such as those based on the force-directed drawing approach, may become uninformative when applied to larger networks with dense or clustered connectivity structure. Methods We implemented a modified layout plug-in, named Multilevel Layout, which applies the conventional layout algorithms within a multilevel optimization framework to better capture the hierarchical modularity of many biological networks. Using a wide variety of real life biological networks, we carried out a systematic evaluation of the method in comparison with other layout algorithms in Cytoscape. Results The multilevel approach provided both biologically relevant and visually pleasant layout solutions in most network types, hence complementing the layout options available in Cytoscape. In particular, it could improve drawing of large-scale networks of yeast genetic interactions and human physical interactions. In more general terms, the biological evaluation framework developed here enables one to assess the layout solutions from any existing or future graph drawing algorithm as well as to optimize their performance for a given network type or structure. Conclusions By making use of the multilevel modular organization when visualizing biological networks, together with the biological evaluation of the layout solutions, one can generate convenient visualizations for many network biology applications. PMID:22448851

  11. Neural practice effect during cross-modal selective attention: Supra-modal and modality-specific effects.

    PubMed

    Xia, Jing; Zhang, Wei; Jiang, Yizhou; Li, You; Chen, Qi

    2018-05-16

    Practice and experiences gradually shape the central nervous system, from the synaptic level to large-scale neural networks. In natural multisensory environment, even when inundated by streams of information from multiple sensory modalities, our brain does not give equal weight to different modalities. Rather, visual information more frequently receives preferential processing and eventually dominates consciousness and behavior, i.e., visual dominance. It remains unknown, however, the supra-modal and modality-specific practice effect during cross-modal selective attention, and moreover whether the practice effect shows similar modality preferences as the visual dominance effect in the multisensory environment. To answer the above two questions, we adopted a cross-modal selective attention paradigm in conjunction with the hybrid fMRI design. Behaviorally, visual performance significantly improved while auditory performance remained constant with practice, indicating that visual attention more flexibly adapted behavior with practice than auditory attention. At the neural level, the practice effect was associated with decreasing neural activity in the frontoparietal executive network and increasing activity in the default mode network, which occurred independently of the modality attended, i.e., the supra-modal mechanisms. On the other hand, functional decoupling between the auditory and the visual system was observed with the progress of practice, which varied as a function of the modality attended. The auditory system was functionally decoupled with both the dorsal and ventral visual stream during auditory attention while was decoupled only with the ventral visual stream during visual attention. To efficiently suppress the irrelevant visual information with practice, auditory attention needs to additionally decouple the auditory system from the dorsal visual stream. The modality-specific mechanisms, together with the behavioral effect, thus support the visual dominance model in terms of the practice effect during cross-modal selective attention. Copyright © 2018 Elsevier Ltd. All rights reserved.

  12. New solutions for climate network visualization

    NASA Astrophysics Data System (ADS)

    Nocke, Thomas; Buschmann, Stefan; Donges, Jonathan F.; Marwan, Norbert

    2016-04-01

    An increasing amount of climate and climate impact research methods deals with geo-referenced networks, including energy, trade, supply-chain, disease dissemination and climatic tele-connection networks. At the same time, the size and complexity of these networks increases, resulting in networks of more than hundred thousand or even millions of edges, which are often temporally evolving, have additional data at nodes and edges, and can consist of multiple layers even in real 3D. This gives challenges to both the static representation and the interactive exploration of these networks, first of all avoiding edge clutter ("edge spagetti") and allowing interactivity even for unfiltered networks. Within this presentation, we illustrate potential solutions to these challenges. Therefore, we give a glimpse on a questionnaire performed with climate and complex system scientists with respect to their network visualization requirements, and on a review of available state-of-the-art visualization techniques and tools for this purpose (see as well Nocke et al., 2015). In the main part, we present alternative visualization solutions for several use cases (global, regional, and multi-layered climate networks) including alternative geographic projections, edge bundling, and 3-D network support (based on CGV and GTX tools), and implementation details to reach interactive frame rates. References: Nocke, T., S. Buschmann, J. F. Donges, N. Marwan, H.-J. Schulz, and C. Tominski: Review: Visual analytics of climate networks, Nonlinear Processes in Geophysics, 22, 545-570, doi:10.5194/npg-22-545-2015, 2015

  13. Decision support systems and methods for complex networks

    DOEpatents

    Huang, Zhenyu [Richland, WA; Wong, Pak Chung [Richland, WA; Ma, Jian [Richland, WA; Mackey, Patrick S [Richland, WA; Chen, Yousu [Richland, WA; Schneider, Kevin P [Seattle, WA

    2012-02-28

    Methods and systems for automated decision support in analyzing operation data from a complex network. Embodiments of the present invention utilize these algorithms and techniques not only to characterize the past and present condition of a complex network, but also to predict future conditions to help operators anticipate deteriorating and/or problem situations. In particular, embodiments of the present invention characterize network conditions from operation data using a state estimator. Contingency scenarios can then be generated based on those network conditions. For at least a portion of all of the contingency scenarios, risk indices are determined that describe the potential impact of each of those scenarios. Contingency scenarios with risk indices are presented visually as graphical representations in the context of a visual representation of the complex network. Analysis of the historical risk indices based on the graphical representations can then provide trends that allow for prediction of future network conditions.

  14. Development of a geographic visualization and communications systems (GVCS) for monitoring remote vehicles

    DOT National Transportation Integrated Search

    1998-03-30

    The purpose of this project is to integrate a variety of geographic information systems : capabilities and telecommunication technologies for potential use in geographic network and : visualization applications. The specific technical goals of the pr...

  15. A medical application integrating remote 3D visualization tools to access picture archiving and communication system on mobile devices.

    PubMed

    He, Longjun; Ming, Xing; Liu, Qian

    2014-04-01

    With computing capability and display size growing, the mobile device has been used as a tool to help clinicians view patient information and medical images anywhere and anytime. However, for direct interactive 3D visualization, which plays an important role in radiological diagnosis, the mobile device cannot provide a satisfactory quality of experience for radiologists. This paper developed a medical system that can get medical images from the picture archiving and communication system on the mobile device over the wireless network. In the proposed application, the mobile device got patient information and medical images through a proxy server connecting to the PACS server. Meanwhile, the proxy server integrated a range of 3D visualization techniques, including maximum intensity projection, multi-planar reconstruction and direct volume rendering, to providing shape, brightness, depth and location information generated from the original sectional images for radiologists. Furthermore, an algorithm that changes remote render parameters automatically to adapt to the network status was employed to improve the quality of experience. Finally, performance issues regarding the remote 3D visualization of the medical images over the wireless network of the proposed application were also discussed. The results demonstrated that this proposed medical application could provide a smooth interactive experience in the WLAN and 3G networks.

  16. PubNet: a flexible system for visualizing literature derived networks

    PubMed Central

    Douglas, Shawn M; Montelione, Gaetano T; Gerstein, Mark

    2005-01-01

    We have developed PubNet, a web-based tool that extracts several types of relationships returned by PubMed queries and maps them into networks, allowing for graphical visualization, textual navigation, and topological analysis. PubNet supports the creation of complex networks derived from the contents of individual citations, such as genes, proteins, Protein Data Bank (PDB) IDs, Medical Subject Headings (MeSH) terms, and authors. This feature allows one to, for example, examine a literature derived network of genes based on functional similarity. PMID:16168087

  17. Secure videoconferencing equipment switching system and method

    DOEpatents

    Dirks, David H; Gomes, Diane; Stewart, Corbin J; Fischer, Robert A

    2013-04-30

    Examples of systems described herein include videoconferencing systems having audio/visual components coupled to a codec. The codec may be configured by a control system. Communication networks having different security levels may be alternately coupled to the codec following appropriate configuration by the control system. The control system may also be coupled to the communication networks.

  18. New Abstraction Networks and a New Visualization Tool in Support of Auditing the SNOMED CT Content

    PubMed Central

    Geller, James; Ochs, Christopher; Perl, Yehoshua; Xu, Junchuan

    2012-01-01

    Medical terminologies are large and complex. Frequently, errors are hidden in this complexity. Our objective is to find such errors, which can be aided by deriving abstraction networks from a large terminology. Abstraction networks preserve important features but eliminate many minor details, which are often not useful for identifying errors. Providing visualizations for such abstraction networks aids auditors by allowing them to quickly focus on elements of interest within a terminology. Previously we introduced area taxonomies and partial area taxonomies for SNOMED CT. In this paper, two advanced, novel kinds of abstraction networks, the relationship-constrained partial area subtaxonomy and the root-constrained partial area subtaxonomy are defined and their benefits are demonstrated. We also describe BLUSNO, an innovative software tool for quickly generating and visualizing these SNOMED CT abstraction networks. BLUSNO is a dynamic, interactive system that provides quick access to well organized information about SNOMED CT. PMID:23304293

  19. New abstraction networks and a new visualization tool in support of auditing the SNOMED CT content.

    PubMed

    Geller, James; Ochs, Christopher; Perl, Yehoshua; Xu, Junchuan

    2012-01-01

    Medical terminologies are large and complex. Frequently, errors are hidden in this complexity. Our objective is to find such errors, which can be aided by deriving abstraction networks from a large terminology. Abstraction networks preserve important features but eliminate many minor details, which are often not useful for identifying errors. Providing visualizations for such abstraction networks aids auditors by allowing them to quickly focus on elements of interest within a terminology. Previously we introduced area taxonomies and partial area taxonomies for SNOMED CT. In this paper, two advanced, novel kinds of abstraction networks, the relationship-constrained partial area subtaxonomy and the root-constrained partial area subtaxonomy are defined and their benefits are demonstrated. We also describe BLUSNO, an innovative software tool for quickly generating and visualizing these SNOMED CT abstraction networks. BLUSNO is a dynamic, interactive system that provides quick access to well organized information about SNOMED CT.

  20. Interactions between Visual Attention and Episodic Retrieval: Dissociable Contributions of Parietal Regions during Gist-Based False Recognition

    PubMed Central

    Guerin, Scott A.; Robbins, Clifford A.; Gilmore, Adrian W.; Schacter, Daniel L.

    2012-01-01

    SUMMARY The interaction between episodic retrieval and visual attention is relatively unexplored. Given that systems mediating attention and episodic memory appear to be segregated, and perhaps even in competition, it is unclear how visual attention is recruited during episodic retrieval. We investigated the recruitment of visual attention during the suppression of gist-based false recognition, the tendency to falsely recognize items that are similar to previously encountered items. Recruitment of visual attention was associated with activity in the dorsal attention network. The inferior parietal lobule, often implicated in episodic retrieval, tracked veridical retrieval of perceptual detail and showed reduced activity during the engagement of visual attention, consistent with a competitive relationship with the dorsal attention network. These findings suggest that the contribution of the parietal cortex to interactions between visual attention and episodic retrieval entails distinct systems that contribute to different components of the task while also suppressing each other. PMID:22998879

  1. A visually guided collision warning system with a neuromorphic architecture.

    PubMed

    Okuno, Hirotsugu; Yagi, Tetsuya

    2008-12-01

    We have designed a visually guided collision warning system with a neuromorphic architecture, employing an algorithm inspired by the visual nervous system of locusts. The system was implemented with mixed analog-digital integrated circuits consisting of an analog resistive network and field-programmable gate array (FPGA) circuits. The resistive network processes the interaction between the laterally spreading excitatory and inhibitory signals instantaneously, which is essential for real-time computation of collision avoidance with a low power consumption and a compact hardware. The system responded selectively to approaching objects of simulated movie images at close range. The system was, however, confronted with serious noise problems due to the vibratory ego-motion, when it was installed in a mobile miniature car. To overcome this problem, we developed the algorithm, which is also installable in FPGA circuits, in order for the system to respond robustly during the ego-motion.

  2. Image understanding systems based on the unifying representation of perceptual and conceptual information and the solution of mid-level and high-level vision problems

    NASA Astrophysics Data System (ADS)

    Kuvychko, Igor

    2001-10-01

    Vision is a part of a larger information system that converts visual information into knowledge structures. These structures drive vision process, resolving ambiguity and uncertainty via feedback, and provide image understanding, that is an interpretation of visual information in terms of such knowledge models. A computer vision system based on such principles requires unifying representation of perceptual and conceptual information. Computer simulation models are built on the basis of graphs/networks. The ability of human brain to emulate similar graph/networks models is found. That means a very important shift of paradigm in our knowledge about brain from neural networks to the cortical software. Starting from the primary visual areas, brain analyzes an image as a graph-type spatial structure. Primary areas provide active fusion of image features on a spatial grid-like structure, where nodes are cortical columns. The spatial combination of different neighbor features cannot be described as a statistical/integral characteristic of the analyzed region, but uniquely characterizes such region itself. Spatial logic and topology naturally present in such structures. Mid-level vision processes like clustering, perceptual grouping, multilevel hierarchical compression, separation of figure from ground, etc. are special kinds of graph/network transformations. They convert low-level image structure into the set of more abstract ones, which represent objects and visual scene, making them easy for analysis by higher-level knowledge structures. Higher-level vision phenomena like shape from shading, occlusion, etc. are results of such analysis. Such approach gives opportunity not only to explain frequently unexplainable results of the cognitive science, but also to create intelligent computer vision systems that simulate perceptional processes in both what and where visual pathways. Such systems can open new horizons for robotic and computer vision industries.

  3. Multiple-region directed functional connectivity based on phase delays.

    PubMed

    Goelman, Gadi; Dan, Rotem

    2017-03-01

    Network analysis is increasingly advancing the field of neuroimaging. Neural networks are generally constructed from pairwise interactions with an assumption of linear relations between them. Here, a high-order statistical framework to calculate directed functional connectivity among multiple regions, using wavelet analysis and spectral coherence has been presented. The mathematical expression for 4 regions was derived and used to characterize a quartet of regions as a linear, combined (nonlinear), or disconnected network. Phase delays between regions were used to obtain network's temporal hierarchy and directionality. The validity of the mathematical derivation along with the effects of coupling strength and noise on its outcomes were studied by computer simulations of the Kuramoto model. The simulations demonstrated correct directionality for a large range of coupling strength and low sensitivity to Gaussian noise compared with pairwise coherences. The analysis was applied to resting-state fMRI data of 40 healthy young subjects to characterize the ventral visual system, motor system and default mode network (DMN). It was shown that the ventral visual system was predominantly composed of linear networks while the motor system and the DMN were composed of combined (nonlinear) networks. The ventral visual system exhibits its known temporal hierarchy, the motor system exhibits center ↔ out hierarchy and the DMN has dorsal ↔ ventral and anterior ↔ posterior organizations. The analysis can be applied in different disciplines such as seismology, or economy and in a variety of brain data including stimulus-driven fMRI, electrophysiology, EEG, and MEG, thus open new horizons in brain research. Hum Brain Mapp 38:1374-1386, 2017. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  4. Visual pathways from the perspective of cost functions and multi-task deep neural networks.

    PubMed

    Scholte, H Steven; Losch, Max M; Ramakrishnan, Kandan; de Haan, Edward H F; Bohte, Sander M

    2018-01-01

    Vision research has been shaped by the seminal insight that we can understand the higher-tier visual cortex from the perspective of multiple functional pathways with different goals. In this paper, we try to give a computational account of the functional organization of this system by reasoning from the perspective of multi-task deep neural networks. Machine learning has shown that tasks become easier to solve when they are decomposed into subtasks with their own cost function. We hypothesize that the visual system optimizes multiple cost functions of unrelated tasks and this causes the emergence of a ventral pathway dedicated to vision for perception, and a dorsal pathway dedicated to vision for action. To evaluate the functional organization in multi-task deep neural networks, we propose a method that measures the contribution of a unit towards each task, applying it to two networks that have been trained on either two related or two unrelated tasks, using an identical stimulus set. Results show that the network trained on the unrelated tasks shows a decreasing degree of feature representation sharing towards higher-tier layers while the network trained on related tasks uniformly shows high degree of sharing. We conjecture that the method we propose can be used to analyze the anatomical and functional organization of the visual system and beyond. We predict that the degree to which tasks are related is a good descriptor of the degree to which they share downstream cortical-units. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Development of a new software for analyzing 3-D fracture network

    NASA Astrophysics Data System (ADS)

    Um, Jeong-Gi; Noh, Young-Hwan; Choi, Yosoon

    2014-05-01

    A new software is presented to analyze fracture network in 3-D. Recently, we completed the software package based on information given in EGU2013. The software consists of several modules that play roles in management of borehole data, stochastic modelling of fracture network, construction of analysis domain, visualization of fracture geometry in 3-D, calculation of equivalent pipes and production of cross-section diagrams. Intel Parallel Studio XE 2013, Visual Studio.NET 2010 and the open source VTK library were utilized as development tools to efficiently implement the modules and the graphical user interface of the software. A case study was performed to analyze 3-D fracture network system at the Upper Devonian Grosmont Formation in Alberta, Canada. The results have suggested that the developed software is effective in modelling and visualizing 3-D fracture network system, and can provide useful information to tackle the geomechanical problems related to strength, deformability and hydraulic behaviours of the fractured rock masses. This presentation describes the concept and details of the development and implementation of the software.

  6. Tools for visually exploring biological networks.

    PubMed

    Suderman, Matthew; Hallett, Michael

    2007-10-15

    Many tools exist for visually exploring biological networks including well-known examples such as Cytoscape, VisANT, Pathway Studio and Patika. These systems play a key role in the development of integrative biology, systems biology and integrative bioinformatics. The trend in the development of these tools is to go beyond 'static' representations of cellular state, towards a more dynamic model of cellular processes through the incorporation of gene expression data, subcellular localization information and time-dependent behavior. We provide a comprehensive review of the relative advantages and disadvantages of existing systems with two goals in mind: to aid researchers in efficiently identifying the appropriate existing tools for data visualization; to describe the necessary and realistic goals for the next generation of visualization tools. In view of the first goal, we provide in the Supplementary Material a systematic comparison of more than 35 existing tools in terms of over 25 different features. Supplementary data are available at Bioinformatics online.

  7. Visual gravitational motion and the vestibular system in humans

    PubMed Central

    Lacquaniti, Francesco; Bosco, Gianfranco; Indovina, Iole; La Scaleia, Barbara; Maffei, Vincenzo; Moscatelli, Alessandro; Zago, Myrka

    2013-01-01

    The visual system is poorly sensitive to arbitrary accelerations, but accurately detects the effects of gravity on a target motion. Here we review behavioral and neuroimaging data about the neural mechanisms for dealing with object motion and egomotion under gravity. The results from several experiments show that the visual estimates of a target motion under gravity depend on the combination of a prior of gravity effects with on-line visual signals on target position and velocity. These estimates are affected by vestibular inputs, and are encoded in a visual-vestibular network whose core regions lie within or around the Sylvian fissure, and are represented by the posterior insula/retroinsula/temporo-parietal junction. This network responds both to target motions coherent with gravity and to vestibular caloric stimulation in human fMRI studies. Transient inactivation of the temporo-parietal junction selectively disrupts the interception of targets accelerated by gravity. PMID:24421761

  8. Visual gravitational motion and the vestibular system in humans.

    PubMed

    Lacquaniti, Francesco; Bosco, Gianfranco; Indovina, Iole; La Scaleia, Barbara; Maffei, Vincenzo; Moscatelli, Alessandro; Zago, Myrka

    2013-12-26

    The visual system is poorly sensitive to arbitrary accelerations, but accurately detects the effects of gravity on a target motion. Here we review behavioral and neuroimaging data about the neural mechanisms for dealing with object motion and egomotion under gravity. The results from several experiments show that the visual estimates of a target motion under gravity depend on the combination of a prior of gravity effects with on-line visual signals on target position and velocity. These estimates are affected by vestibular inputs, and are encoded in a visual-vestibular network whose core regions lie within or around the Sylvian fissure, and are represented by the posterior insula/retroinsula/temporo-parietal junction. This network responds both to target motions coherent with gravity and to vestibular caloric stimulation in human fMRI studies. Transient inactivation of the temporo-parietal junction selectively disrupts the interception of targets accelerated by gravity.

  9. New software for 3D fracture network analysis and visualization

    NASA Astrophysics Data System (ADS)

    Song, J.; Noh, Y.; Choi, Y.; Um, J.; Hwang, S.

    2013-12-01

    This study presents new software to perform analysis and visualization of the fracture network system in 3D. The developed software modules for the analysis and visualization, such as BOUNDARY, DISK3D, FNTWK3D, CSECT and BDM, have been developed using Microsoft Visual Basic.NET and Visualization TookKit (VTK) open-source library. Two case studies revealed that each module plays a role in construction of analysis domain, visualization of fracture geometry in 3D, calculation of equivalent pipes, production of cross-section map and management of borehole data, respectively. The developed software for analysis and visualization of the 3D fractured rock mass can be used to tackle the geomechanical problems related to strength, deformability and hydraulic behaviors of the fractured rock masses.

  10. Software-codec-based full motion video conferencing on the PC using visual pattern image sequence coding

    NASA Astrophysics Data System (ADS)

    Barnett, Barry S.; Bovik, Alan C.

    1995-04-01

    This paper presents a real time full motion video conferencing system based on the Visual Pattern Image Sequence Coding (VPISC) software codec. The prototype system hardware is comprised of two personal computers, two camcorders, two frame grabbers, and an ethernet connection. The prototype system software has a simple structure. It runs under the Disk Operating System, and includes a user interface, a video I/O interface, an event driven network interface, and a free running or frame synchronous video codec that also acts as the controller for the video and network interfaces. Two video coders have been tested in this system. Simple implementations of Visual Pattern Image Coding and VPISC have both proven to support full motion video conferencing with good visual quality. Future work will concentrate on expanding this prototype to support the motion compensated version of VPISC, as well as encompassing point-to-point modem I/O and multiple network protocols. The application will be ported to multiple hardware platforms and operating systems. The motivation for developing this prototype system is to demonstrate the practicality of software based real time video codecs. Furthermore, software video codecs are not only cheaper, but are more flexible system solutions because they enable different computer platforms to exchange encoded video information without requiring on-board protocol compatible video codex hardware. Software based solutions enable true low cost video conferencing that fits the `open systems' model of interoperability that is so important for building portable hardware and software applications.

  11. Synaptic and Network Mechanisms of Sparse and Reliable Visual Cortical Activity during Nonclassical Receptive Field Stimulation

    PubMed Central

    Haider, Bilal; Krause, Matthew R.; Duque, Alvaro; Yu, Yuguo; Touryan, Jonathan; Mazer, James A.; McCormick, David A.

    2011-01-01

    SUMMARY During natural vision, the entire visual field is stimulated by images rich in spatiotemporal structure. Although many visual system studies restrict stimuli to the classical receptive field (CRF), it is known that costimulation of the CRF and the surrounding nonclassical receptive field (nCRF) increases neuronal response sparseness. The cellular and network mechanisms underlying increased response sparseness remain largely unexplored. Here we show that combined CRF + nCRF stimulation increases the sparseness, reliability, and precision of spiking and membrane potential responses in classical regular spiking (RSC) pyramidal neurons of cat primary visual cortex. Conversely, fast-spiking interneurons exhibit increased activity and decreased selectivity during CRF + nCRF stimulation. The increased sparseness and reliability of RSC neuron spiking is associated with increased inhibitory barrages and narrower visually evoked synaptic potentials. Our experimental observations were replicated with a simple computational model, suggesting that network interactions among neuronal subtypes ultimately sharpen recurrent excitation, producing specific and reliable visual responses. PMID:20152117

  12. A framework for visualization of battlefield network behavior

    NASA Astrophysics Data System (ADS)

    Perzov, Yury; Yurcik, William

    2006-05-01

    An extensible network simulation application was developed to study wireless battlefield communications. The application monitors node mobility and depicts broadcast and unicast traffic as expanding rings and directed links. The network simulation was specially designed to support fault injection to show the impact of air strikes on disabling nodes. The application takes standard ns-2 trace files as an input and provides for performance data output in different graphical forms (histograms and x/y plots). Network visualization via animation of simulation output can be saved in AVI format that may serve as a basis for a real-time battlefield awareness system.

  13. Evaluation of the traffic parameters in a metropolitan area by fusing visual perceptions and CNN processing of webcam images.

    PubMed

    Faro, Alberto; Giordano, Daniela; Spampinato, Concetto

    2008-06-01

    This paper proposes a traffic monitoring architecture based on a high-speed communication network whose nodes are equipped with fuzzy processors and cellular neural network (CNN) embedded systems. It implements a real-time mobility information system where visual human perceptions sent by people working on the territory and video-sequences of traffic taken from webcams are jointly processed to evaluate the fundamental traffic parameters for every street of a metropolitan area. This paper presents the whole methodology for data collection and analysis and compares the accuracy and the processing time of the proposed soft computing techniques with other existing algorithms. Moreover, this paper discusses when and why it is recommended to fuse the visual perceptions of the traffic with the automated measurements taken from the webcams to compute the maximum traveling time that is likely needed to reach any destination in the traffic network.

  14. Simple Smartphone-Based Guiding System for Visually Impaired People

    PubMed Central

    Lin, Bor-Shing; Lee, Cheng-Che; Chiang, Pei-Ying

    2017-01-01

    Visually impaired people are often unaware of dangers in front of them, even in familiar environments. Furthermore, in unfamiliar environments, such people require guidance to reduce the risk of colliding with obstacles. This study proposes a simple smartphone-based guiding system for solving the navigation problems for visually impaired people and achieving obstacle avoidance to enable visually impaired people to travel smoothly from a beginning point to a destination with greater awareness of their surroundings. In this study, a computer image recognition system and smartphone application were integrated to form a simple assisted guiding system. Two operating modes, online mode and offline mode, can be chosen depending on network availability. When the system begins to operate, the smartphone captures the scene in front of the user and sends the captured images to the backend server to be processed. The backend server uses the faster region convolutional neural network algorithm or the you only look once algorithm to recognize multiple obstacles in every image, and it subsequently sends the results back to the smartphone. The results of obstacle recognition in this study reached 60%, which is sufficient for assisting visually impaired people in realizing the types and locations of obstacles around them. PMID:28608811

  15. Simple Smartphone-Based Guiding System for Visually Impaired People.

    PubMed

    Lin, Bor-Shing; Lee, Cheng-Che; Chiang, Pei-Ying

    2017-06-13

    Visually impaired people are often unaware of dangers in front of them, even in familiar environments. Furthermore, in unfamiliar environments, such people require guidance to reduce the risk of colliding with obstacles. This study proposes a simple smartphone-based guiding system for solving the navigation problems for visually impaired people and achieving obstacle avoidance to enable visually impaired people to travel smoothly from a beginning point to a destination with greater awareness of their surroundings. In this study, a computer image recognition system and smartphone application were integrated to form a simple assisted guiding system. Two operating modes, online mode and offline mode, can be chosen depending on network availability. When the system begins to operate, the smartphone captures the scene in front of the user and sends the captured images to the backend server to be processed. The backend server uses the faster region convolutional neural network algorithm or the you only look once algorithm to recognize multiple obstacles in every image, and it subsequently sends the results back to the smartphone. The results of obstacle recognition in this study reached 60%, which is sufficient for assisting visually impaired people in realizing the types and locations of obstacles around them.

  16. Designing an End-to-End System for Data Storage, Analysis, and Visualization for an Urban Environmental Observatory

    NASA Astrophysics Data System (ADS)

    McGuire, M. P.; Welty, C.; Gangopadhyay, A.; Karabatis, G.; Chen, Z.

    2006-05-01

    The urban environment is formed by complex interactions between natural and human dominated systems, the study of which requires the collection and analysis of very large datasets that span many disciplines. Recent advances in sensor technology and automated data collection have improved the ability to monitor urban environmental systems and are making the idea of an urban environmental observatory a reality. This in turn has created a number of potential challenges in data management and analysis. We present the design of an end-to-end system to store, analyze, and visualize data from a prototype urban environmental observatory based at the Baltimore Ecosystem Study, a National Science Foundation Long Term Ecological Research site (BES LTER). We first present an object-relational design of an operational database to store high resolution spatial datasets as well as data from sensor networks, archived data from the BES LTER, data from external sources such as USGS NWIS, EPA Storet, and metadata. The second component of the system design includes a spatiotemporal data warehouse consisting of a data staging plan and a multidimensional data model designed for the spatiotemporal analysis of monitoring data. The system design also includes applications for multi-resolution exploratory data analysis, multi-resolution data mining, and spatiotemporal visualization based on the spatiotemporal data warehouse. Also the system design includes interfaces with water quality models such as HSPF, SWMM, and SWAT, and applications for real-time sensor network visualization, data discovery, data download, QA/QC, and backup and recovery, all of which are based on the operational database. The system design includes both internet and workstation-based interfaces. Finally we present the design of a laboratory for spatiotemporal analysis and visualization as well as real-time monitoring of the sensor network.

  17. Visual monitoring of autonomous life sciences experimentation

    NASA Technical Reports Server (NTRS)

    Blank, G. E.; Martin, W. N.

    1987-01-01

    The design and implementation of a computerized visual monitoring system to aid in the monitoring and control of life sciences experiments on board a space station was investigated. A likely multiprocessor design was chosen, a plausible life science experiment with which to work was defined, the theoretical issues involved in the programming of a visual monitoring system for the experiment was considered on the multiprocessor, a system for monitoring the experiment was designed, and simulations of such a system was implemented on a network of Apollo workstations.

  18. Visualization of Traffic Accidents

    NASA Technical Reports Server (NTRS)

    Wang, Jie; Shen, Yuzhong; Khattak, Asad

    2010-01-01

    Traffic accidents have tremendous impact on society. Annually approximately 6.4 million vehicle accidents are reported by police in the US and nearly half of them result in catastrophic injuries. Visualizations of traffic accidents using geographic information systems (GIS) greatly facilitate handling and analysis of traffic accidents in many aspects. Environmental Systems Research Institute (ESRI), Inc. is the world leader in GIS research and development. ArcGIS, a software package developed by ESRI, has the capabilities to display events associated with a road network, such as accident locations, and pavement quality. But when event locations related to a road network are processed, the existing algorithm used by ArcGIS does not utilize all the information related to the routes of the road network and produces erroneous visualization results of event locations. This software bug causes serious problems for applications in which accurate location information is critical for emergency responses, such as traffic accidents. This paper aims to address this problem and proposes an improved method that utilizes all relevant information of traffic accidents, namely, route number, direction, and mile post, and extracts correct event locations for accurate traffic accident visualization and analysis. The proposed method generates a new shape file for traffic accidents and displays them on top of the existing road network in ArcGIS. Visualization of traffic accidents along Hampton Roads Bridge Tunnel is included to demonstrate the effectiveness of the proposed method.

  19. Information processing in the primate visual system - An integrated systems perspective

    NASA Technical Reports Server (NTRS)

    Van Essen, David C.; Anderson, Charles H.; Felleman, Daniel J.

    1992-01-01

    The primate visual system contains dozens of distinct areas in the cerebral cortex and several major subcortical structures. These subdivisions are extensively interconnected in a distributed hierarchical network that contains several intertwined processing streams. A number of strategies are used for efficient information processing within this hierarchy. These include linear and nonlinear filtering, passage through information bottlenecks, and coordinated use of multiple types of information. In addition, dynamic regulation of information flow within and between visual areas may provide the computational flexibility needed for the visual system to perform a broad spectrum of tasks accurately and at high resolution.

  20. Spectral properties of the temporal evolution of brain network structure.

    PubMed

    Wang, Rong; Zhang, Zhen-Zhen; Ma, Jun; Yang, Yong; Lin, Pan; Wu, Ying

    2015-12-01

    The temporal evolution properties of the brain network are crucial for complex brain processes. In this paper, we investigate the differences in the dynamic brain network during resting and visual stimulation states in a task-positive subnetwork, task-negative subnetwork, and whole-brain network. The dynamic brain network is first constructed from human functional magnetic resonance imaging data based on the sliding window method, and then the eigenvalues corresponding to the network are calculated. We use eigenvalue analysis to analyze the global properties of eigenvalues and the random matrix theory (RMT) method to measure the local properties. For global properties, the shifting of the eigenvalue distribution and the decrease in the largest eigenvalue are linked to visual stimulation in all networks. For local properties, the short-range correlation in eigenvalues as measured by the nearest neighbor spacing distribution is not always sensitive to visual stimulation. However, the long-range correlation in eigenvalues as evaluated by spectral rigidity and number variance not only predicts the universal behavior of the dynamic brain network but also suggests non-consistent changes in different networks. These results demonstrate that the dynamic brain network is more random for the task-positive subnetwork and whole-brain network under visual stimulation but is more regular for the task-negative subnetwork. Our findings provide deeper insight into the importance of spectral properties in the functional brain network, especially the incomparable role of RMT in revealing the intrinsic properties of complex systems.

  1. Spectral properties of the temporal evolution of brain network structure

    NASA Astrophysics Data System (ADS)

    Wang, Rong; Zhang, Zhen-Zhen; Ma, Jun; Yang, Yong; Lin, Pan; Wu, Ying

    2015-12-01

    The temporal evolution properties of the brain network are crucial for complex brain processes. In this paper, we investigate the differences in the dynamic brain network during resting and visual stimulation states in a task-positive subnetwork, task-negative subnetwork, and whole-brain network. The dynamic brain network is first constructed from human functional magnetic resonance imaging data based on the sliding window method, and then the eigenvalues corresponding to the network are calculated. We use eigenvalue analysis to analyze the global properties of eigenvalues and the random matrix theory (RMT) method to measure the local properties. For global properties, the shifting of the eigenvalue distribution and the decrease in the largest eigenvalue are linked to visual stimulation in all networks. For local properties, the short-range correlation in eigenvalues as measured by the nearest neighbor spacing distribution is not always sensitive to visual stimulation. However, the long-range correlation in eigenvalues as evaluated by spectral rigidity and number variance not only predicts the universal behavior of the dynamic brain network but also suggests non-consistent changes in different networks. These results demonstrate that the dynamic brain network is more random for the task-positive subnetwork and whole-brain network under visual stimulation but is more regular for the task-negative subnetwork. Our findings provide deeper insight into the importance of spectral properties in the functional brain network, especially the incomparable role of RMT in revealing the intrinsic properties of complex systems.

  2. Visualization techniques for computer network defense

    NASA Astrophysics Data System (ADS)

    Beaver, Justin M.; Steed, Chad A.; Patton, Robert M.; Cui, Xiaohui; Schultz, Matthew

    2011-06-01

    Effective visual analysis of computer network defense (CND) information is challenging due to the volume and complexity of both the raw and analyzed network data. A typical CND is comprised of multiple niche intrusion detection tools, each of which performs network data analysis and produces a unique alerting output. The state-of-the-practice in the situational awareness of CND data is the prevalent use of custom-developed scripts by Information Technology (IT) professionals to retrieve, organize, and understand potential threat events. We propose a new visual analytics framework, called the Oak Ridge Cyber Analytics (ORCA) system, for CND data that allows an operator to interact with all detection tool outputs simultaneously. Aggregated alert events are presented in multiple coordinated views with timeline, cluster, and swarm model analysis displays. These displays are complemented with both supervised and semi-supervised machine learning classifiers. The intent of the visual analytics framework is to improve CND situational awareness, to enable an analyst to quickly navigate and analyze thousands of detected events, and to combine sophisticated data analysis techniques with interactive visualization such that patterns of anomalous activities may be more easily identified and investigated.

  3. Bridging the Host-Network Divide: Survey, Taxonomy, and Solution

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fink, Glenn A.; Duggirala, Vedavyas; Correa, Ricardo

    2007-04-17

    Abstract: "This paper presents a new direction in security awareness tools for system administration--the Host-Network (HoNe) Visualizer. Our requirements for the HoNe Visualizer come from needs system administrators expressed in interviews, from reviewing the literature, and from conducting usability studies with prototypes. We present a tool taxonomy that serves as a framework for our literature review, and we use the taxonomy to show what is missing in the administrator's arsenal. Then we unveil our tool and its supporting infrastructure that we believe will fill the empty niche. We found that most security tools provide either an internal view of amore » host or an external view of traffic on a network. Our interviewees revealed how they must construct a mental end-to-end view from separate tools that individually give an incomplete view, expending valuable time and mental effort. Because of limitations designed into TCP/IP [RFC-791, RFC-793], no tool can effectively correlate host and network data into an end-to-end view without kernel modifications. Currently, no other visualization exists to support end-to-end analysis. But HoNe's infrastructure overcomes TCP/IP's limitations bridging the network and transport layers in the network stack and making end-to-end correlation possible. The capstone is the HoNe Visualizer that amplifies the users' cognitive power and reduces their mental workload by illustrating the correlated data graphically. Users said HoNe would be particularly good for discovering day-zero exploits. Our usability study revealed that users performed better on intrusion detection tasks using our visualization than with tools they were accustomed to using regardless of their experience level."« less

  4. Complex Digital Visual Systems

    ERIC Educational Resources Information Center

    Sweeny, Robert W.

    2013-01-01

    This article identifies possibilities for data visualization as art educational research practice. The author presents an analysis of the relationship between works of art and digital visual culture, employing aspects of network analysis drawn from the work of Barabási, Newman, and Watts (2006) and Castells (1994). Describing complex network…

  5. US Army Research Laboratory Visualization Framework Architecture Document

    DTIC Science & Technology

    2018-01-11

    this report are not to be construed as an official Department of the Army position unless so designated by other authorized documents. Citation of...release; distribution is unlimited. 14. ABSTRACT Visualization of network science experimentation results is generally achieved using stovepipe...report documents the ARL Visualization Framework system design and specific details of its implementation. 15. SUBJECT TERMS visualization

  6. A low complexity visualization tool that helps to perform complex systems analysis

    NASA Astrophysics Data System (ADS)

    Beiró, M. G.; Alvarez-Hamelin, J. I.; Busch, J. R.

    2008-12-01

    In this paper, we present an extension of large network visualization (LaNet-vi), a tool to visualize large scale networks using the k-core decomposition. One of the new features is how vertices compute their angular position. While in the later version it is done using shell clusters, in this version we use the angular coordinate of vertices in higher k-shells, and arrange the highest shell according to a cliques decomposition. The time complexity goes from O(n\\sqrt n) to O(n) upon bounds on a heavy-tailed degree distribution. The tool also performs a k-core-connectivity analysis, highlighting vertices that are not k-connected; e.g. this property is useful to measure robustness or quality of service (QoS) capabilities in communication networks. Finally, the actual version of LaNet-vi can draw labels and all the edges using transparencies, yielding an accurate visualization. Based on the obtained figure, it is possible to distinguish different sources and types of complex networks at a glance, in a sort of 'network iris-print'.

  7. NV: Nessus Vulnerability Visualization for the Web

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Harrison, Lane; Spahn, Riley B; Iannacone, Michael D

    2012-01-01

    Network vulnerability is a critical component of network se- curity. Yet vulnerability analysis has received relatively lit- tle attention from the security visualization community. In this paper we describe nv, a web-based Nessus vulnerability visualization. Nv utilizes treemaps and linked histograms to allow system administrators to discover, analyze, and man- age vulnerabilities on their networks. In addition to visual- izing single Nessus scans, nv supports the analysis of sequen- tial scans by showing which vulnerabilities have been fixed, remain open, or are newly discovered. Nv was also designed to operate completely in-browser, to avoid sending sensitive data to outside servers.more » We discuss the design of nv, as well as provide case studies demonstrating vulnerability analysis workflows which include a multiple-node testbed and data from the 2011 VAST Challenge.« less

  8. Large-Scale Brain Systems in ADHD: Beyond the Prefrontal-Striatal Model

    PubMed Central

    Castellanos, F. Xavier; Proal, Erika

    2012-01-01

    Attention-deficit/hyperactivity disorder (ADHD) has long been thought to reflect dysfunction of prefrontal-striatal circuitry, with involvement of other circuits largely ignored. Recent advances in systems neuroscience-based approaches to brain dysfunction enable the development of models of ADHD pathophysiology that encompass a number of different large-scale “resting state” networks. Here we review progress in delineating large-scale neural systems and illustrate their relevance to ADHD. We relate frontoparietal, dorsal attentional, motor, visual, and default networks to the ADHD functional and structural literature. Insights emerging from mapping intrinsic brain connectivity networks provide a potentially mechanistic framework for understanding aspects of ADHD, such as neuropsychological and behavioral inconsistency, and the possible role of primary visual cortex in attentional dysfunction in the disorder. PMID:22169776

  9. Netgram: Visualizing Communities in Evolving Networks

    PubMed Central

    Mall, Raghvendra; Langone, Rocco; Suykens, Johan A. K.

    2015-01-01

    Real-world complex networks are dynamic in nature and change over time. The change is usually observed in the interactions within the network over time. Complex networks exhibit community like structures. A key feature of the dynamics of complex networks is the evolution of communities over time. Several methods have been proposed to detect and track the evolution of these groups over time. However, there is no generic tool which visualizes all the aspects of group evolution in dynamic networks including birth, death, splitting, merging, expansion, shrinkage and continuation of groups. In this paper, we propose Netgram: a tool for visualizing evolution of communities in time-evolving graphs. Netgram maintains evolution of communities over 2 consecutive time-stamps in tables which are used to create a query database using the sql outer-join operation. It uses a line-based visualization technique which adheres to certain design principles and aesthetic guidelines. Netgram uses a greedy solution to order the initial community information provided by the evolutionary clustering technique such that we have fewer line cross-overs in the visualization. This makes it easier to track the progress of individual communities in time evolving graphs. Netgram is a generic toolkit which can be used with any evolutionary community detection algorithm as illustrated in our experiments. We use Netgram for visualization of topic evolution in the NIPS conference over a period of 11 years and observe the emergence and merging of several disciplines in the field of information processing systems. PMID:26356538

  10. Triage Visualization for Digital Media Exploitation

    DTIC Science & Technology

    2013-09-01

    and responding to threats. Previous work includes NVisionIP [17], a network visualization 8 tool that processes Argus NetFlow [18] data. NVisionIP...2012.02.021 [17] K. Lakkaraju et al., “Nvisionip: netflow visualizations of system state for security situational awareness,” in Proceedings of the 2004 ACM

  11. Reward processing in the value-driven attention network: reward signals tracking cue identity and location.

    PubMed

    Anderson, Brian A

    2017-03-01

    Through associative reward learning, arbitrary cues acquire the ability to automatically capture visual attention. Previous studies have examined the neural correlates of value-driven attentional orienting, revealing elevated activity within a network of brain regions encompassing the visual corticostriatal loop [caudate tail, lateral occipital complex (LOC) and early visual cortex] and intraparietal sulcus (IPS). Such attentional priority signals raise a broader question concerning how visual signals are combined with reward signals during learning to create a representation that is sensitive to the confluence of the two. This study examines reward signals during the cued reward training phase commonly used to generate value-driven attentional biases. High, compared with low, reward feedback preferentially activated the value-driven attention network, in addition to regions typically implicated in reward processing. Further examination of these reward signals within the visual system revealed information about the identity of the preceding cue in the caudate tail and LOC, and information about the location of the preceding cue in IPS, while early visual cortex represented both location and identity. The results reveal teaching signals within the value-driven attention network during associative reward learning, and further suggest functional specialization within different regions of this network during the acquisition of an integrated representation of stimulus value. © The Author (2016). Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  12. Hardware Neural Network for a Visual Inspection System

    NASA Astrophysics Data System (ADS)

    Chun, Seungwoo; Hayakawa, Yoshihiro; Nakajima, Koji

    The visual inspection of defects in products is heavily dependent on human experience and instinct. In this situation, it is difficult to reduce the production costs and to shorten the inspection time and hence the total process time. Consequently people involved in this area desire an automatic inspection system. In this paper, we propose a hardware neural network, which is expected to provide high-speed operation for automatic inspection of products. Since neural networks can learn, this is a suitable method for self-adjustment of criteria for classification. To achieve high-speed operation, we use parallel and pipelining techniques. Furthermore, we use a piecewise linear function instead of a conventional activation function in order to save hardware resources. Consequently, our proposed hardware neural network achieved 6GCPS and 2GCUPS, which in our test sample proved to be sufficiently fast.

  13. Automated visual inspection system based on HAVNET architecture

    NASA Astrophysics Data System (ADS)

    Burkett, K.; Ozbayoglu, Murat A.; Dagli, Cihan H.

    1994-10-01

    In this study, the HAusdorff-Voronoi NETwork (HAVNET) developed at the UMR Smart Engineering Systems Lab is tested in the recognition of mounted circuit components commonly used in printed circuit board assembly systems. The automated visual inspection system used consists of a CCD camera, a neural network based image processing software and a data acquisition card connected to a PC. The experiments are run in the Smart Engineering Systems Lab in the Engineering Management Dept. of the University of Missouri-Rolla. The performance analysis shows that the vision system is capable of recognizing different components under uncontrolled lighting conditions without being effected by rotation or scale differences. The results obtained are promising and the system can be used in real manufacturing environments. Currently the system is being customized for a specific manufacturing application.

  14. The neural representation of the gender of faces in the primate visual system: A computer modeling study.

    PubMed

    Minot, Thomas; Dury, Hannah L; Eguchi, Akihiro; Humphreys, Glyn W; Stringer, Simon M

    2017-03-01

    We use an established neural network model of the primate visual system to show how neurons might learn to encode the gender of faces. The model consists of a hierarchy of 4 competitive neuronal layers with associatively modifiable feedforward synaptic connections between successive layers. During training, the network was presented with many realistic images of male and female faces, during which the synaptic connections are modified using biologically plausible local associative learning rules. After training, we found that different subsets of output neurons have learned to respond exclusively to either male or female faces. With the inclusion of short range excitation within each neuronal layer to implement a self-organizing map architecture, neurons representing either male or female faces were clustered together in the output layer. This learning process is entirely unsupervised, as the gender of the face images is not explicitly labeled and provided to the network as a supervisory training signal. These simulations are extended to training the network on rotating faces. It is found that by using a trace learning rule incorporating a temporal memory trace of recent neuronal activity, neurons responding selectively to either male or female faces were also able to learn to respond invariantly over different views of the faces. This kind of trace learning has been previously shown to operate within the primate visual system by neurophysiological and psychophysical studies. The computer simulations described here predict that similar neurons encoding the gender of faces will be present within the primate visual system. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  15. Location accuracy evaluation of lightning location systems using natural lightning flashes recorded by a network of high-speed cameras

    NASA Astrophysics Data System (ADS)

    Alves, J.; Saraiva, A. C. V.; Campos, L. Z. D. S.; Pinto, O., Jr.; Antunes, L.

    2014-12-01

    This work presents a method for the evaluation of location accuracy of all Lightning Location System (LLS) in operation in southeastern Brazil, using natural cloud-to-ground (CG) lightning flashes. This can be done through a multiple high-speed cameras network (RAMMER network) installed in the Paraiba Valley region - SP - Brazil. The RAMMER network (Automated Multi-camera Network for Monitoring and Study of Lightning) is composed by four high-speed cameras operating at 2,500 frames per second. Three stationary black-and-white (B&W) cameras were situated in the cities of São José dos Campos and Caçapava. A fourth color camera was mobile (installed in a car), but operated in a fixed location during the observation period, within the city of São José dos Campos. The average distance among cameras was 13 kilometers. Each RAMMER sensor position was determined so that the network can observe the same lightning flash from different angles and all recorded videos were GPS (Global Position System) time stamped, allowing comparisons of events between cameras and the LLS. The RAMMER sensor is basically composed by a computer, a Phantom high-speed camera version 9.1 and a GPS unit. The lightning cases analyzed in the present work were observed by at least two cameras, their position was visually triangulated and the results compared with BrasilDAT network, during the summer seasons of 2011/2012 and 2012/2013. The visual triangulation method is presented in details. The calibration procedure showed an accuracy of 9 meters between the accurate GPS position of the object triangulated and the result from the visual triangulation method. Lightning return stroke positions, estimated with the visual triangulation method, were compared with LLS locations. Differences between solutions were not greater than 1.8 km.

  16. A System for Video Surveillance and Monitoring CMU VSAM Final Report

    DTIC Science & Technology

    1999-11-30

    motion-based skeletonization, neural network , spatio-temporal salience Patterns inside image chips, spurious motion rejection, model -based... network of sensors with respect to the model coordinate system, computation of 3D geolocation estimates, and graphical display of object hypotheses...rithms have been developed. The first uses view dependent visual properties to train a neural network classifier to recognize four classes: single

  17. Understanding interfirm relationships in business ecosystems with interactive visualization.

    PubMed

    Basole, Rahul C; Clear, Trustin; Hu, Mengdie; Mehrotra, Harshit; Stasko, John

    2013-12-01

    Business ecosystems are characterized by large, complex, and global networks of firms, often from many different market segments, all collaborating, partnering, and competing to create and deliver new products and services. Given the rapidly increasing scale, complexity, and rate of change of business ecosystems, as well as economic and competitive pressures, analysts are faced with the formidable task of quickly understanding the fundamental characteristics of these interfirm networks. Existing tools, however, are predominantly query- or list-centric with limited interactive, exploratory capabilities. Guided by a field study of corporate analysts, we have designed and implemented dotlink360, an interactive visualization system that provides capabilities to gain systemic insight into the compositional, temporal, and connective characteristics of business ecosystems. dotlink360 consists of novel, multiple connected views enabling the analyst to explore, discover, and understand interfirm networks for a focal firm, specific market segments or countries, and the entire business ecosystem. System evaluation by a small group of prototypical users shows supporting evidence of the benefits of our approach. This design study contributes to the relatively unexplored, but promising area of exploratory information visualization in market research and business strategy.

  18. GLO-STIX: Graph-Level Operations for Specifying Techniques and Interactive eXploration

    PubMed Central

    Stolper, Charles D.; Kahng, Minsuk; Lin, Zhiyuan; Foerster, Florian; Goel, Aakash; Stasko, John; Chau, Duen Horng

    2015-01-01

    The field of graph visualization has produced a wealth of visualization techniques for accomplishing a variety of analysis tasks. Therefore analysts often rely on a suite of different techniques, and visual graph analysis application builders strive to provide this breadth of techniques. To provide a holistic model for specifying network visualization techniques (as opposed to considering each technique in isolation) we present the Graph-Level Operations (GLO) model. We describe a method for identifying GLOs and apply it to identify five classes of GLOs, which can be flexibly combined to re-create six canonical graph visualization techniques. We discuss advantages of the GLO model, including potentially discovering new, effective network visualization techniques and easing the engineering challenges of building multi-technique graph visualization applications. Finally, we implement the GLOs that we identified into the GLO-STIX prototype system that enables an analyst to interactively explore a graph by applying GLOs. PMID:26005315

  19. A Novel Distributed Privacy Paradigm for Visual Sensor Networks Based on Sharing Dynamical Systems

    NASA Astrophysics Data System (ADS)

    Luh, William; Kundur, Deepa; Zourntos, Takis

    2006-12-01

    Visual sensor networks (VSNs) provide surveillance images/video which must be protected from eavesdropping and tampering en route to the base station. In the spirit of sensor networks, we propose a novel paradigm for securing privacy and confidentiality in a distributed manner. Our paradigm is based on the control of dynamical systems, which we show is well suited for VSNs due to its low complexity in terms of processing and communication, while achieving robustness to both unintentional noise and intentional attacks as long as a small subset of nodes are affected. We also present a low complexity algorithm called TANGRAM to demonstrate the feasibility of applying our novel paradigm to VSNs. We present and discuss simulation results of TANGRAM.

  20. An open-source software platform for data management, visualisation, model building and model sharing in water, energy and other resource modelling domains.

    NASA Astrophysics Data System (ADS)

    Knox, S.; Meier, P.; Mohammed, K.; Korteling, B.; Matrosov, E. S.; Hurford, A.; Huskova, I.; Harou, J. J.; Rosenberg, D. E.; Thilmant, A.; Medellin-Azuara, J.; Wicks, J.

    2015-12-01

    Capacity expansion on resource networks is essential to adapting to economic and population growth and pressures such as climate change. Engineered infrastructure systems such as water, energy, or transport networks require sophisticated and bespoke models to refine management and investment strategies. Successful modeling of such complex systems relies on good data management and advanced methods to visualize and share data.Engineered infrastructure systems are often represented as networks of nodes and links with operating rules describing their interactions. Infrastructure system management and planning can be abstracted to simulating or optimizing new operations and extensions of the network. By separating the data storage of abstract networks from manipulation and modeling we have created a system where infrastructure modeling across various domains is facilitated.We introduce Hydra Platform, a Free Open Source Software designed for analysts and modelers to store, manage and share network topology and data. Hydra Platform is a Python library with a web service layer for remote applications, called Apps, to connect. Apps serve various functions including network or results visualization, data export (e.g. into a proprietary format) or model execution. This Client-Server architecture allows users to manipulate and share centrally stored data. XML templates allow a standardised description of the data structure required for storing network data such that it is compatible with specific models.Hydra Platform represents networks in an abstract way and is therefore not bound to a single modeling domain. It is the Apps that create domain-specific functionality. Using Apps researchers from different domains can incorporate different models within the same network enabling cross-disciplinary modeling while minimizing errors and streamlining data sharing. Separating the Python library from the web layer allows developers to natively expand the software or build web-based apps in other languages for remote functionality. Partner CH2M is developing a commercial user-interface for Hydra Platform however custom interfaces and visualization tools can be built. Hydra Platform is available on GitHub while Apps will be shared on a central repository.

  1. An Unmanned Aerial Vehicle Cluster Network Cruise System for Monitor

    NASA Astrophysics Data System (ADS)

    Jiang, Jirong; Tao, Jinpeng; Xin, Guipeng

    2018-06-01

    The existing maritime cruising system mainly uses manned motorboats to monitor the quality of coastal water and patrol and maintenance of the navigation -aiding facility, which has the problems of high energy consumption, small range of cruise for monitoring, insufficient information control and low visualization. In recent years, the application of UAS in the maritime field has alleviated the phenomenon above to some extent. A cluster-based unmanned network monitoring cruise system designed in this project uses the floating small UAV self-powered launching platform as a carrier, applys the idea of cluster, and combines the strong controllability of the multi-rotor UAV and the capability to carry customized modules, constituting a unmanned, visualized and normalized monitoring cruise network to realize the functions of maritime cruise, maintenance of navigational-aiding and monitoring the quality of coastal water.

  2. A Multimodal Neural Network Recruited by Expertise with Musical Notation

    ERIC Educational Resources Information Center

    Wong, Yetta Kwailing; Gauthier, Isabel

    2010-01-01

    Prior neuroimaging work on visual perceptual expertise has focused on changes in the visual system, ignoring possible effects of acquiring expert visual skills in nonvisual areas. We investigated expertise for reading musical notation, a skill likely to be associated with multimodal abilities. We compared brain activity in music-reading experts…

  3. CellNetVis: a web tool for visualization of biological networks using force-directed layout constrained by cellular components.

    PubMed

    Heberle, Henry; Carazzolle, Marcelo Falsarella; Telles, Guilherme P; Meirelles, Gabriela Vaz; Minghim, Rosane

    2017-09-13

    The advent of "omics" science has brought new perspectives in contemporary biology through the high-throughput analyses of molecular interactions, providing new clues in protein/gene function and in the organization of biological pathways. Biomolecular interaction networks, or graphs, are simple abstract representations where the components of a cell (e.g. proteins, metabolites etc.) are represented by nodes and their interactions are represented by edges. An appropriate visualization of data is crucial for understanding such networks, since pathways are related to functions that occur in specific regions of the cell. The force-directed layout is an important and widely used technique to draw networks according to their topologies. Placing the networks into cellular compartments helps to quickly identify where network elements are located and, more specifically, concentrated. Currently, only a few tools provide the capability of visually organizing networks by cellular compartments. Most of them cannot handle large and dense networks. Even for small networks with hundreds of nodes the available tools are not able to reposition the network while the user is interacting, limiting the visual exploration capability. Here we propose CellNetVis, a web tool to easily display biological networks in a cell diagram employing a constrained force-directed layout algorithm. The tool is freely available and open-source. It was originally designed for networks generated by the Integrated Interactome System and can be used with networks from others databases, like InnateDB. CellNetVis has demonstrated to be applicable for dynamic investigation of complex networks over a consistent representation of a cell on the Web, with capabilities not matched elsewhere.

  4. Corridor One:An Integrated Distance Visualization Enuronments for SSI+ASCI Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Christopher R. Johnson, Charles D. Hansen

    2001-10-29

    The goal of Corridor One: An Integrated Distance Visualization Environment for ASCI and SSI Application was to combine the forces of six leading edge laboratories working in the areas of visualization and distributed computing and high performance networking (Argonne National Laboratory, Lawrence Berkeley National Laboratory, Los Alamos National Laboratory, University of Illinois, University of Utah and Princeton University) to develop and deploy the most advanced integrated distance visualization environment for large-scale scientific visualization and demonstrate it on applications relevant to the DOE SSI and ASCI programs. The Corridor One team brought world class expertise in parallel rendering, deep image basedmore » rendering, immersive environment technology, large-format multi-projector wall based displays, volume and surface visualization algorithms, collaboration tools and streaming media technology, network protocols for image transmission, high-performance networking, quality of service technology and distributed computing middleware. Our strategy was to build on the very successful teams that produced the I-WAY, ''Computational Grids'' and CAVE technology and to add these to the teams that have developed the fastest parallel visualizations systems and the most widely used networking infrastructure for multicast and distributed media. Unfortunately, just as we were getting going on the Corridor One project, DOE cut the program after the first year. As such, our final report consists of our progress during year one of the grant.« less

  5. Static and dynamic views of visual cortical organization.

    PubMed

    Casagrande, Vivien A; Xu, Xiangmin; Sáry, Gyula

    2002-01-01

    Without the aid of modern techniques Cajal speculated that cells in the visual cortex were connected in circuits. From Cajal's time until fairly recently, the flow of information within the cells and circuits of visual cortex has been described as progressing from input to output, from sensation to action. In this chapter we argue that a paradigm shift in our concept of the visual cortical neuron is under way. The most important change in our view concerns the neuron's functional role. Visual cortical neurons do not have static functional signatures but instead function dynamically depending on the ongoing activity of the networks to which they belong. These networks are not merely top-down or bottom-up unidirectional transmission lines, but rather represent machinery that uses recurrent information and is dynamic and highly adaptable. With the advancement of technology for analyzing the conversations of multiple neurons at many levels in the visual system and higher resolution imaging, we predict that the paradigm shift will progress to the point where neurons are no longer viewed as independent processing units but as members of subsets of networks where their role is mapped in space-time coordinates in relationship to the other neuronal members. This view moves us far from Cajal's original views of the neuron. Nevertheless, we believe that understanding the basic morphology and wiring of networks will continue to contribute to our overall understanding of the visual cortex.

  6. Weighted link graphs: a distributed IDS for secondary intrusion detection and defense

    NASA Astrophysics Data System (ADS)

    Zhou, Mian; Lang, Sheau-Dong

    2005-03-01

    While a firewall installed at the perimeter of a local network provides the first line of defense against the hackers, many intrusion incidents are the results of successful penetration of the firewalls. One computer"s compromise often put the entire network at risk. In this paper, we propose an IDS that provides a finer control over the internal network. The system focuses on the variations of connection-based behavior of each single computer, and uses a weighted link graph to visualize the overall traffic abnormalities. The functionality of our system is of a distributed personal IDS system that also provides a centralized traffic analysis by graphical visualization. We use a novel weight assignment schema for the local detection within each end agent. The local abnormalities are quantitatively carried out by the node weight and link weight and further sent to the central analyzer to build the weighted link graph. Thus, we distribute the burden of traffic processing and visualization to each agent and make it more efficient for the overall intrusion detection. As the LANs are more vulnerable to inside attacks, our system is designed as a reinforcement to prevent corruption from the inside.

  7. Discovering Network Structure Beyond Communities

    NASA Astrophysics Data System (ADS)

    Nishikawa, Takashi; Motter, Adilson E.

    2011-11-01

    To understand the formation, evolution, and function of complex systems, it is crucial to understand the internal organization of their interaction networks. Partly due to the impossibility of visualizing large complex networks, resolving network structure remains a challenging problem. Here we overcome this difficulty by combining the visual pattern recognition ability of humans with the high processing speed of computers to develop an exploratory method for discovering groups of nodes characterized by common network properties, including but not limited to communities of densely connected nodes. Without any prior information about the nature of the groups, the method simultaneously identifies the number of groups, the group assignment, and the properties that define these groups. The results of applying our method to real networks suggest the possibility that most group structures lurk undiscovered in the fast-growing inventory of social, biological, and technological networks of scientific interest.

  8. Visualization Techniques for Computer Network Defense

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beaver, Justin M; Steed, Chad A; Patton, Robert M

    2011-01-01

    Effective visual analysis of computer network defense (CND) information is challenging due to the volume and complexity of both the raw and analyzed network data. A typical CND is comprised of multiple niche intrusion detection tools, each of which performs network data analysis and produces a unique alerting output. The state-of-the-practice in the situational awareness of CND data is the prevalent use of custom-developed scripts by Information Technology (IT) professionals to retrieve, organize, and understand potential threat events. We propose a new visual analytics framework, called the Oak Ridge Cyber Analytics (ORCA) system, for CND data that allows an operatormore » to interact with all detection tool outputs simultaneously. Aggregated alert events are presented in multiple coordinated views with timeline, cluster, and swarm model analysis displays. These displays are complemented with both supervised and semi-supervised machine learning classifiers. The intent of the visual analytics framework is to improve CND situational awareness, to enable an analyst to quickly navigate and analyze thousands of detected events, and to combine sophisticated data analysis techniques with interactive visualization such that patterns of anomalous activities may be more easily identified and investigated.« less

  9. Genonets server-a web server for the construction, analysis and visualization of genotype networks.

    PubMed

    Khalid, Fahad; Aguilar-Rodríguez, José; Wagner, Andreas; Payne, Joshua L

    2016-07-08

    A genotype network is a graph in which vertices represent genotypes that have the same phenotype. Edges connect vertices if their corresponding genotypes differ in a single small mutation. Genotype networks are used to study the organization of genotype spaces. They have shed light on the relationship between robustness and evolvability in biological systems as different as RNA macromolecules and transcriptional regulatory circuits. Despite the importance of genotype networks, no tool exists for their automatic construction, analysis and visualization. Here we fill this gap by presenting the Genonets Server, a tool that provides the following features: (i) the construction of genotype networks for categorical and univariate phenotypes from DNA, RNA, amino acid or binary sequences; (ii) analyses of genotype network topology and how it relates to robustness and evolvability, as well as analyses of genotype network topography and how it relates to the navigability of a genotype network via mutation and natural selection; (iii) multiple interactive visualizations that facilitate exploratory research and education. The Genonets Server is freely available at http://ieu-genonets.uzh.ch. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  10. Biographer: web-based editing and rendering of SBGN compliant biochemical networks.

    PubMed

    Krause, Falko; Schulz, Marvin; Ripkens, Ben; Flöttmann, Max; Krantz, Marcus; Klipp, Edda; Handorf, Thomas

    2013-06-01

    The rapid accumulation of knowledge in the field of Systems Biology during the past years requires advanced, but simple-to-use, methods for the visualization of information in a structured and easily comprehensible manner. We have developed biographer, a web-based renderer and editor for reaction networks, which can be integrated as a library into tools dealing with network-related information. Our software enables visualizations based on the emerging standard Systems Biology Graphical Notation. It is able to import networks encoded in various formats such as SBML, SBGN-ML and jSBGN, a custom lightweight exchange format. The core package is implemented in HTML5, CSS and JavaScript and can be used within any kind of web-based project. It features interactive graph-editing tools and automatic graph layout algorithms. In addition, we provide a standalone graph editor and a web server, which contains enhanced features like web services for the import and export of models and visualizations in different formats. The biographer tool can be used at and downloaded from the web page http://biographer.biologie.hu-berlin.de/. The different software packages, including a server-independent version as well as a web server for Windows and Linux based systems, are available at http://code.google.com/p/biographer/ under the open-source license LGPL

  11. Visual behavior characterization for intrusion and misuse detection

    NASA Astrophysics Data System (ADS)

    Erbacher, Robert F.; Frincke, Deborah

    2001-05-01

    As computer and network intrusions become more and more of a concern, the need for better capabilities, to assist in the detection and analysis of intrusions also increase. System administrators typically rely on log files to analyze usage and detect misuse. However, as a consequence of the amount of data collected by each machine, multiplied by the tens or hundreds of machines under the system administrator's auspices, the entirety of the data available is neither collected nor analyzed. This is compounded by the need to analyze network traffic data as well. We propose a methodology for analyzing network and computer log information visually based on the analysis of the behavior of the users. Each user's behavior is the key to determining their intent and overriding activity, whether they attempt to hide their actions or not. Proficient hackers will attempt to hide their ultimate activities, which hinders the reliability of log file analysis. Visually analyzing the users''s behavior however, is much more adaptable and difficult to counteract.

  12. CollaborationViz: Interactive Visual Exploration of Biomedical Research Collaboration Networks

    PubMed Central

    Bian, Jiang; Xie, Mengjun; Hudson, Teresa J.; Eswaran, Hari; Brochhausen, Mathias; Hanna, Josh; Hogan, William R.

    2014-01-01

    Social network analysis (SNA) helps us understand patterns of interaction between social entities. A number of SNA studies have shed light on the characteristics of research collaboration networks (RCNs). Especially, in the Clinical Translational Science Award (CTSA) community, SNA provides us a set of effective tools to quantitatively assess research collaborations and the impact of CTSA. However, descriptive network statistics are difficult for non-experts to understand. In this article, we present our experiences of building meaningful network visualizations to facilitate a series of visual analysis tasks. The basis of our design is multidimensional, visual aggregation of network dynamics. The resulting visualizations can help uncover hidden structures in the networks, elicit new observations of the network dynamics, compare different investigators and investigator groups, determine critical factors to the network evolution, and help direct further analyses. We applied our visualization techniques to explore the biomedical RCNs at the University of Arkansas for Medical Sciences – a CTSA institution. And, we created CollaborationViz, an open-source visual analytical tool to help network researchers and administration apprehend the network dynamics of research collaborations through interactive visualization. PMID:25405477

  13. Behavior analysis for elderly care using a network of low-resolution visual sensors

    NASA Astrophysics Data System (ADS)

    Eldib, Mohamed; Deboeverie, Francis; Philips, Wilfried; Aghajan, Hamid

    2016-07-01

    Recent advancements in visual sensor technologies have made behavior analysis practical for in-home monitoring systems. The current in-home monitoring systems face several challenges: (1) visual sensor calibration is a difficult task and not practical in real-life because of the need for recalibration when the visual sensors are moved accidentally by a caregiver or the senior citizen, (2) privacy concerns, and (3) the high hardware installation cost. We propose to use a network of cheap low-resolution visual sensors (30×30 pixels) for long-term behavior analysis. The behavior analysis starts by visual feature selection based on foreground/background detection to track the motion level in each visual sensor. Then a hidden Markov model (HMM) is used to estimate the user's locations without calibration. Finally, an activity discovery approach is proposed using spatial and temporal contexts. We performed experiments on 10 months of real-life data. We show that the HMM approach outperforms the k-nearest neighbor classifier against ground truth for 30 days. Our framework is able to discover 13 activities of daily livings (ADL parameters). More specifically, we analyze mobility patterns and some of the key ADL parameters to detect increasing or decreasing health conditions.

  14. Integrated web visualizations for protein-protein interaction databases.

    PubMed

    Jeanquartier, Fleur; Jean-Quartier, Claire; Holzinger, Andreas

    2015-06-16

    Understanding living systems is crucial for curing diseases. To achieve this task we have to understand biological networks based on protein-protein interactions. Bioinformatics has come up with a great amount of databases and tools that support analysts in exploring protein-protein interactions on an integrated level for knowledge discovery. They provide predictions and correlations, indicate possibilities for future experimental research and fill the gaps to complete the picture of biochemical processes. There are numerous and huge databases of protein-protein interactions used to gain insights into answering some of the many questions of systems biology. Many computational resources integrate interaction data with additional information on molecular background. However, the vast number of diverse Bioinformatics resources poses an obstacle to the goal of understanding. We present a survey of databases that enable the visual analysis of protein networks. We selected M=10 out of N=53 resources supporting visualization, and we tested against the following set of criteria: interoperability, data integration, quantity of possible interactions, data visualization quality and data coverage. The study reveals differences in usability, visualization features and quality as well as the quantity of interactions. StringDB is the recommended first choice. CPDB presents a comprehensive dataset and IntAct lets the user change the network layout. A comprehensive comparison table is available via web. The supplementary table can be accessed on http://tinyurl.com/PPI-DB-Comparison-2015. Only some web resources featuring graph visualization can be successfully applied to interactive visual analysis of protein-protein interaction. Study results underline the necessity for further enhancements of visualization integration in biochemical analysis tools. Identified challenges are data comprehensiveness, confidence, interactive feature and visualization maturing.

  15. PetriScape - A plugin for discrete Petri net simulations in Cytoscape.

    PubMed

    Almeida, Diogo; Azevedo, Vasco; Silva, Artur; Baumbach, Jan

    2016-06-04

    Systems biology plays a central role for biological network analysis in the post-genomic era. Cytoscape is the standard bioinformatics tool offering the community an extensible platform for computational analysis of the emerging cellular network together with experimental omics data sets. However, only few apps/plugins/tools are available for simulating network dynamics in Cytoscape 3. Many approaches of varying complexity exist but none of them have been integrated into Cytoscape as app/plugin yet. Here, we introduce PetriScape, the first Petri net simulator for Cytoscape. Although discrete Petri nets are quite simplistic models, they are capable of modeling global network properties and simulating their behaviour. In addition, they are easily understood and well visualizable. PetriScape comes with the following main functionalities: (1) import of biological networks in SBML format, (2) conversion into a Petri net, (3) visualization as Petri net, and (4) simulation and visualization of the token flow in Cytoscape. PetriScape is the first Cytoscape plugin for Petri nets. It allows a straightforward Petri net model creation, simulation and visualization with Cytoscape, providing clues about the activity of key components in biological networks.

  16. PetriScape - A plugin for discrete Petri net simulations in Cytoscape.

    PubMed

    Almeida, Diogo; Azevedo, Vasco; Silva, Artur; Baumbach, Jan

    2016-03-01

    Systems biology plays a central role for biological network analysis in the post-genomic era. Cytoscape is the standard bioinformatics tool offering the community an extensible platform for computational analysis of the emerging cellular network together with experimental omics data sets. However, only few apps/plugins/tools are available for simulating network dynamics in Cytoscape 3. Many approaches of varying complexity exist but none of them have been integrated into Cytoscape as app/plugin yet. Here, we introduce PetriScape, the first Petri net simulator for Cytoscape. Although discrete Petri nets are quite simplistic models, they are capable of modeling global network properties and simulating their behaviour. In addition, they are easily understood and well visualizable. PetriScape comes with the following main functionalities: (1) import of biological networks in SBML format, (2) conversion into a Petri net, (3) visualization as Petri net, and (4) simulation and visualization of the token flow in Cytoscape. PetriScape is the first Cytoscape plugin for Petri nets. It allows a straightforward Petri net model creation, simulation and visualization with Cytoscape, providing clues about the activity of key components in biological networks.

  17. A computational model of the development of separate representations of facial identity and expression in the primate visual system.

    PubMed

    Tromans, James Matthew; Harris, Mitchell; Stringer, Simon Maitland

    2011-01-01

    Experimental studies have provided evidence that the visual processing areas of the primate brain represent facial identity and facial expression within different subpopulations of neurons. For example, in non-human primates there is evidence that cells within the inferior temporal gyrus (TE) respond primarily to facial identity, while cells within the superior temporal sulcus (STS) respond to facial expression. More recently, it has been found that the orbitofrontal cortex (OFC) of non-human primates contains some cells that respond exclusively to changes in facial identity, while other cells respond exclusively to facial expression. How might the primate visual system develop physically separate representations of facial identity and expression given that the visual system is always exposed to simultaneous combinations of facial identity and expression during learning? In this paper, a biologically plausible neural network model, VisNet, of the ventral visual pathway is trained on a set of carefully-designed cartoon faces with different identities and expressions. The VisNet model architecture is composed of a hierarchical series of four Self-Organising Maps (SOMs), with associative learning in the feedforward synaptic connections between successive layers. During learning, the network develops separate clusters of cells that respond exclusively to either facial identity or facial expression. We interpret the performance of the network in terms of the learning properties of SOMs, which are able to exploit the statistical indendependence between facial identity and expression.

  18. Power Grid Maintenance Scheduling Intelligence Arrangement Supporting System Based on Power Flow Forecasting

    NASA Astrophysics Data System (ADS)

    Xie, Chang; Wen, Jing; Liu, Wenying; Wang, Jiaming

    With the development of intelligent dispatching, the intelligence level of network control center full-service urgent need to raise. As an important daily work of network control center, the application of maintenance scheduling intelligent arrangement to achieve high-quality and safety operation of power grid is very important. By analyzing the shortages of the traditional maintenance scheduling software, this paper designs a power grid maintenance scheduling intelligence arrangement supporting system based on power flow forecasting, which uses the advanced technologies in maintenance scheduling, such as artificial intelligence, online security checking, intelligent visualization techniques. It implements the online security checking of maintenance scheduling based on power flow forecasting and power flow adjusting based on visualization, in order to make the maintenance scheduling arrangement moreintelligent and visual.

  19. End-to-End Multimodal Emotion Recognition Using Deep Neural Networks

    NASA Astrophysics Data System (ADS)

    Tzirakis, Panagiotis; Trigeorgis, George; Nicolaou, Mihalis A.; Schuller, Bjorn W.; Zafeiriou, Stefanos

    2017-12-01

    Automatic affect recognition is a challenging task due to the various modalities emotions can be expressed with. Applications can be found in many domains including multimedia retrieval and human computer interaction. In recent years, deep neural networks have been used with great success in determining emotional states. Inspired by this success, we propose an emotion recognition system using auditory and visual modalities. To capture the emotional content for various styles of speaking, robust features need to be extracted. To this purpose, we utilize a Convolutional Neural Network (CNN) to extract features from the speech, while for the visual modality a deep residual network (ResNet) of 50 layers. In addition to the importance of feature extraction, a machine learning algorithm needs also to be insensitive to outliers while being able to model the context. To tackle this problem, Long Short-Term Memory (LSTM) networks are utilized. The system is then trained in an end-to-end fashion where - by also taking advantage of the correlations of the each of the streams - we manage to significantly outperform the traditional approaches based on auditory and visual handcrafted features for the prediction of spontaneous and natural emotions on the RECOLA database of the AVEC 2016 research challenge on emotion recognition.

  20. Visualization maps for the evolution of research hotspots in the field of regional health information networks.

    PubMed

    Wang, Yanjun; Zheng, Jianzhong; Zhang, Ailian; Zhou, Wei; Dong, Haiyuan

    2018-03-01

    The aim of this study was to reveal research hotspots in the field of regional health information networks (RHINs) and use visualization techniques to explore their evolution over time and differences between countries. We conducted a literature review for a 50-year period and compared the prevalence of certain index terms during the periods 1963-1993 and 1994-2014 and in six countries. We applied keyword frequency analysis, keyword co-occurrence analysis, multidimensional scaling analysis, and network visualization technology. The total number of keywords was found to increase with time. From 1994 to 2014, the research priorities shifted from hospital planning to community health planning. The number of keywords reflecting information-based research increased. The density of the knowledge network increased significantly, and partial keywords condensed into knowledge groups. All six countries focus on keywords including Information Systems; Telemedicine; Information Service; Medical Records Systems, Computerized; Internet; etc.; however, the level of development and some research priorities are different. RHIN research has generally increased in popularity over the past 50 years. The research hotspots are evolving and are at different levels of development in different countries. Knowledge network mapping and perceptual maps provide useful information for scholars, managers, and policy-makers.

  1. Universal brain systems for recognizing word shapes and handwriting gestures during reading

    PubMed Central

    Nakamura, Kimihiro; Kuo, Wen-Jui; Pegado, Felipe; Cohen, Laurent; Tzeng, Ovid J. L.; Dehaene, Stanislas

    2012-01-01

    Do the neural circuits for reading vary across culture? Reading of visually complex writing systems such as Chinese has been proposed to rely on areas outside the classical left-hemisphere network for alphabetic reading. Here, however, we show that, once potential confounds in cross-cultural comparisons are controlled for by presenting handwritten stimuli to both Chinese and French readers, the underlying network for visual word recognition may be more universal than previously suspected. Using functional magnetic resonance imaging in a semantic task with words written in cursive font, we demonstrate that two universal circuits, a shape recognition system (reading by eye) and a gesture recognition system (reading by hand), are similarly activated and show identical patterns of activation and repetition priming in the two language groups. These activations cover most of the brain regions previously associated with culture-specific tuning. Our results point to an extended reading network that invariably comprises the occipitotemporal visual word-form system, which is sensitive to well-formed static letter strings, and a distinct left premotor region, Exner’s area, which is sensitive to the forward or backward direction with which cursive letters are dynamically presented. These findings suggest that cultural effects in reading merely modulate a fixed set of invariant macroscopic brain circuits, depending on surface features of orthographies. PMID:23184998

  2. Age-dependent modulation of the somatosensory network upon eye closure.

    PubMed

    Brodoehl, Stefan; Klingner, Carsten; Witte, Otto W

    2016-02-01

    Eye closure even in complete darkness can improve somatosensory perception by switching the brain to a uni-sensory processing mode. This causes an increased information flow between the thalamus and the somatosensory cortex while decreasing modulation by the visual cortex. Previous work suggests that these modulations are age-dependent and that the benefit in somatosensory performance due to eye closing diminishes with age. The cause of this age-dependency and to what extent somatosensory processing is involved remains unclear. Therefore, we intended to characterize the underlying age-dependent modifications in the interaction and connectivity of different sensory networks caused by eye closure. We performed functional MR-imaging with tactile stimulation of the right hand under the conditions of opened and closed eyes in healthy young and elderly participants. Conditional Granger causality analysis was performed to assess the somatosensory and visual networks, including the thalamus. Independent of age, eye closure improved the information transfer from the thalamus to and within the somatosensory cortex. However, beyond that, we found an age-dependent recruitment strategy. Whereas young participants were characterized by an optimized information flow within the relays of the somatosensory network, elderly participants revealed a stronger modulatory influence of the visual network upon the somatosensory cortex. Our results demonstrate that the modulation of the somatosensory and visual networks by eye closure diminishes with age and that the dominance of the visual system is more pronounced in the aging brain. Copyright © 2015 Elsevier B.V. All rights reserved.

  3. An integrated network visualization framework towards metabolic engineering applications.

    PubMed

    Noronha, Alberto; Vilaça, Paulo; Rocha, Miguel

    2014-12-30

    Over the last years, several methods for the phenotype simulation of microorganisms, under specified genetic and environmental conditions have been proposed, in the context of Metabolic Engineering (ME). These methods provided insight on the functioning of microbial metabolism and played a key role in the design of genetic modifications that can lead to strains of industrial interest. On the other hand, in the context of Systems Biology research, biological network visualization has reinforced its role as a core tool in understanding biological processes. However, it has been scarcely used to foster ME related methods, in spite of the acknowledged potential. In this work, an open-source software that aims to fill the gap between ME and metabolic network visualization is proposed, in the form of a plugin to the OptFlux ME platform. The framework is based on an abstract layer, where the network is represented as a bipartite graph containing minimal information about the underlying entities and their desired relative placement. The framework provides input/output support for networks specified in standard formats, such as XGMML, SBGN or SBML, providing a connection to genome-scale metabolic models. An user-interface makes it possible to edit, manipulate and query nodes in the network, providing tools to visualize diverse effects, including visual filters and aspect changing (e.g. colors, shapes and sizes). These tools are particularly interesting for ME, since they allow overlaying phenotype simulation results or elementary flux modes over the networks. The framework and its source code are freely available, together with documentation and other resources, being illustrated with well documented case studies.

  4. Distinctive Correspondence Between Separable Visual Attention Functions and Intrinsic Brain Networks

    PubMed Central

    Ruiz-Rizzo, Adriana L.; Neitzel, Julia; Müller, Hermann J.; Sorg, Christian; Finke, Kathrin

    2018-01-01

    Separable visual attention functions are assumed to rely on distinct but interacting neural mechanisms. Bundesen's “theory of visual attention” (TVA) allows the mathematical estimation of independent parameters that characterize individuals' visual attentional capacity (i.e., visual processing speed and visual short-term memory storage capacity) and selectivity functions (i.e., top-down control and spatial laterality). However, it is unclear whether these parameters distinctively map onto different brain networks obtained from intrinsic functional connectivity, which organizes slowly fluctuating ongoing brain activity. In our study, 31 demographically homogeneous healthy young participants performed whole- and partial-report tasks and underwent resting-state functional magnetic resonance imaging (rs-fMRI). Report accuracy was modeled using TVA to estimate, individually, the four TVA parameters. Networks encompassing cortical areas relevant for visual attention were derived from independent component analysis of rs-fMRI data: visual, executive control, right and left frontoparietal, and ventral and dorsal attention networks. Two TVA parameters were mapped on particular functional networks. First, participants with higher (vs. lower) visual processing speed showed lower functional connectivity within the ventral attention network. Second, participants with more (vs. less) efficient top-down control showed higher functional connectivity within the dorsal attention network and lower functional connectivity within the visual network. Additionally, higher performance was associated with higher functional connectivity between networks: specifically, between the ventral attention and right frontoparietal networks for visual processing speed, and between the visual and executive control networks for top-down control. The higher inter-network functional connectivity was related to lower intra-network connectivity. These results demonstrate that separable visual attention parameters that are assumed to constitute relatively stable traits correspond distinctly to the functional connectivity both within and between particular functional networks. This implies that individual differences in basic attention functions are represented by differences in the coherence of slowly fluctuating brain activity. PMID:29662444

  5. Distinctive Correspondence Between Separable Visual Attention Functions and Intrinsic Brain Networks.

    PubMed

    Ruiz-Rizzo, Adriana L; Neitzel, Julia; Müller, Hermann J; Sorg, Christian; Finke, Kathrin

    2018-01-01

    Separable visual attention functions are assumed to rely on distinct but interacting neural mechanisms. Bundesen's "theory of visual attention" (TVA) allows the mathematical estimation of independent parameters that characterize individuals' visual attentional capacity (i.e., visual processing speed and visual short-term memory storage capacity) and selectivity functions (i.e., top-down control and spatial laterality). However, it is unclear whether these parameters distinctively map onto different brain networks obtained from intrinsic functional connectivity, which organizes slowly fluctuating ongoing brain activity. In our study, 31 demographically homogeneous healthy young participants performed whole- and partial-report tasks and underwent resting-state functional magnetic resonance imaging (rs-fMRI). Report accuracy was modeled using TVA to estimate, individually, the four TVA parameters. Networks encompassing cortical areas relevant for visual attention were derived from independent component analysis of rs-fMRI data: visual, executive control, right and left frontoparietal, and ventral and dorsal attention networks. Two TVA parameters were mapped on particular functional networks. First, participants with higher (vs. lower) visual processing speed showed lower functional connectivity within the ventral attention network. Second, participants with more (vs. less) efficient top-down control showed higher functional connectivity within the dorsal attention network and lower functional connectivity within the visual network. Additionally, higher performance was associated with higher functional connectivity between networks: specifically, between the ventral attention and right frontoparietal networks for visual processing speed, and between the visual and executive control networks for top-down control. The higher inter-network functional connectivity was related to lower intra-network connectivity. These results demonstrate that separable visual attention parameters that are assumed to constitute relatively stable traits correspond distinctly to the functional connectivity both within and between particular functional networks. This implies that individual differences in basic attention functions are represented by differences in the coherence of slowly fluctuating brain activity.

  6. Network portal: a database for storage, analysis and visualization of biological networks

    PubMed Central

    Turkarslan, Serdar; Wurtmann, Elisabeth J.; Wu, Wei-Ju; Jiang, Ning; Bare, J. Christopher; Foley, Karen; Reiss, David J.; Novichkov, Pavel; Baliga, Nitin S.

    2014-01-01

    The ease of generating high-throughput data has enabled investigations into organismal complexity at the systems level through the inference of networks of interactions among the various cellular components (genes, RNAs, proteins and metabolites). The wider scientific community, however, currently has limited access to tools for network inference, visualization and analysis because these tasks often require advanced computational knowledge and expensive computing resources. We have designed the network portal (http://networks.systemsbiology.net) to serve as a modular database for the integration of user uploaded and public data, with inference algorithms and tools for the storage, visualization and analysis of biological networks. The portal is fully integrated into the Gaggle framework to seamlessly exchange data with desktop and web applications and to allow the user to create, save and modify workspaces, and it includes social networking capabilities for collaborative projects. While the current release of the database contains networks for 13 prokaryotic organisms from diverse phylogenetic clades (4678 co-regulated gene modules, 3466 regulators and 9291 cis-regulatory motifs), it will be rapidly populated with prokaryotic and eukaryotic organisms as relevant data become available in public repositories and through user input. The modular architecture, simple data formats and open API support community development of the portal. PMID:24271392

  7. Virtual Environments for Visualizing Structural Health Monitoring Sensor Networks, Data, and Metadata.

    PubMed

    Napolitano, Rebecca; Blyth, Anna; Glisic, Branko

    2018-01-16

    Visualization of sensor networks, data, and metadata is becoming one of the most pivotal aspects of the structural health monitoring (SHM) process. Without the ability to communicate efficiently and effectively between disparate groups working on a project, an SHM system can be underused, misunderstood, or even abandoned. For this reason, this work seeks to evaluate visualization techniques in the field, identify flaws in current practices, and devise a new method for visualizing and accessing SHM data and metadata in 3D. More precisely, the work presented here reflects a method and digital workflow for integrating SHM sensor networks, data, and metadata into a virtual reality environment by combining spherical imaging and informational modeling. Both intuitive and interactive, this method fosters communication on a project enabling diverse practitioners of SHM to efficiently consult and use the sensor networks, data, and metadata. The method is presented through its implementation on a case study, Streicker Bridge at Princeton University campus. To illustrate the efficiency of the new method, the time and data file size were compared to other potential methods used for visualizing and accessing SHM sensor networks, data, and metadata in 3D. Additionally, feedback from civil engineering students familiar with SHM is used for validation. Recommendations on how different groups working together on an SHM project can create SHM virtual environment and convey data to proper audiences, are also included.

  8. Virtual Environments for Visualizing Structural Health Monitoring Sensor Networks, Data, and Metadata

    PubMed Central

    Napolitano, Rebecca; Blyth, Anna; Glisic, Branko

    2018-01-01

    Visualization of sensor networks, data, and metadata is becoming one of the most pivotal aspects of the structural health monitoring (SHM) process. Without the ability to communicate efficiently and effectively between disparate groups working on a project, an SHM system can be underused, misunderstood, or even abandoned. For this reason, this work seeks to evaluate visualization techniques in the field, identify flaws in current practices, and devise a new method for visualizing and accessing SHM data and metadata in 3D. More precisely, the work presented here reflects a method and digital workflow for integrating SHM sensor networks, data, and metadata into a virtual reality environment by combining spherical imaging and informational modeling. Both intuitive and interactive, this method fosters communication on a project enabling diverse practitioners of SHM to efficiently consult and use the sensor networks, data, and metadata. The method is presented through its implementation on a case study, Streicker Bridge at Princeton University campus. To illustrate the efficiency of the new method, the time and data file size were compared to other potential methods used for visualizing and accessing SHM sensor networks, data, and metadata in 3D. Additionally, feedback from civil engineering students familiar with SHM is used for validation. Recommendations on how different groups working together on an SHM project can create SHM virtual environment and convey data to proper audiences, are also included. PMID:29337877

  9. Generalized Cartographic and Simultaneous Representation of Utility Networks for Decision-Support Systems and Crisis Management in Urban Environments

    NASA Astrophysics Data System (ADS)

    Becker, T.; König, G.

    2015-10-01

    Cartographic visualizations of crises are used to create a Common Operational Picture (COP) and enforce Situational Awareness by presenting relevant information to the involved actors. As nearly all crises affect geospatial entities, geo-data representations have to support location-specific analysis throughout the decision-making process. Meaningful cartographic presentation is needed for coordinating the activities of crisis manager in a highly dynamic situation, since operators' attention span and their spatial memories are limiting factors during the perception and interpretation process. Situational Awareness of operators in conjunction with a COP are key aspects in decision-making process and essential for making well thought-out and appropriate decisions. Considering utility networks as one of the most complex and particularly frequent required systems in urban environment, meaningful cartographic presentation of multiple utility networks with respect to disaster management do not exist. Therefore, an optimized visualization of utility infrastructure for emergency response procedures is proposed. The article will describe a conceptual approach on how to simplify, aggregate, and visualize multiple utility networks and their components to meet the requirements of the decision-making process and to support Situational Awareness.

  10. Dynamic facial expressions evoke distinct activation in the face perception network: a connectivity analysis study.

    PubMed

    Foley, Elaine; Rippon, Gina; Thai, Ngoc Jade; Longe, Olivia; Senior, Carl

    2012-02-01

    Very little is known about the neural structures involved in the perception of realistic dynamic facial expressions. In the present study, a unique set of naturalistic dynamic facial emotional expressions was created. Through fMRI and connectivity analysis, a dynamic face perception network was identified, which is demonstrated to extend Haxby et al.'s [Haxby, J. V., Hoffman, E. A., & Gobbini, M. I. The distributed human neural system for face perception. Trends in Cognitive Science, 4, 223-233, 2000] distributed neural system for face perception. This network includes early visual regions, such as the inferior occipital gyrus, which is identified as insensitive to motion or affect but sensitive to the visual stimulus, the STS, identified as specifically sensitive to motion, and the amygdala, recruited to process affect. Measures of effective connectivity between these regions revealed that dynamic facial stimuli were associated with specific increases in connectivity between early visual regions, such as the inferior occipital gyrus and the STS, along with coupling between the STS and the amygdala, as well as the inferior frontal gyrus. These findings support the presence of a distributed network of cortical regions that mediate the perception of different dynamic facial expressions.

  11. Bioinformatics Analysis of Protein Phosphorylation in Plant Systems Biology Using P3DB.

    PubMed

    Yao, Qiuming; Xu, Dong

    2017-01-01

    Protein phosphorylation is one of the most pervasive protein post-translational modification events in plant cells. It is involved in many plant biological processes, such as plant growth, organ development, and plant immunology, by regulating or switching signaling and metabolic pathways. High-throughput experimental methods like mass spectrometry can easily characterize hundreds to thousands of phosphorylation events in a single experiment. With the increasing volume of the data sets, Plant Protein Phosphorylation DataBase (P3DB, http://p3db.org ) provides a comprehensive, systematic, and interactive online platform to deposit, query, analyze, and visualize these phosphorylation events in many plant species. It stores the protein phosphorylation sites in the context of identified mass spectra, phosphopeptides, and phosphoproteins contributed from various plant proteome studies. In addition, P3DB associates these plant phosphorylation sites to protein physicochemical information in the protein charts and tertiary structures, while various protein annotations from hierarchical kinase phosphatase families, protein domains, and gene ontology are also added into the database. P3DB not only provides rich information, but also interconnects and provides visualization of the data in networks, in systems biology context. Currently, P3DB includes the KiC (Kinase Client) assay network, the protein-protein interaction network, the kinase-substrate network, the phosphatase-substrate network, and the protein domain co-occurrence network. All of these are available to query for and visualize existing phosphorylation events. Although P3DB only hosts experimentally identified phosphorylation data, it provides a plant phosphorylation prediction model for any unknown queries on the fly. P3DB is an entry point to the plant phosphorylation community to deposit and visualize any customized data sets within this systems biology framework. Nowadays, P3DB has become one of the major bioinformatics platforms of protein phosphorylation in plant biology.

  12. Concepts to Support HRP Integration Using Publications and Modeling

    NASA Technical Reports Server (NTRS)

    Mindock, J.; Lumpkins, S.; Shelhamer, M.

    2014-01-01

    Initial efforts are underway to enhance the Human Research Program (HRP)'s identification and support of potential cross-disciplinary scientific collaborations. To increase the emphasis on integration in HRP's science portfolio management, concepts are being explored through the development of a set of tools. These tools are intended to enable modeling, analysis, and visualization of the state of the human system in the spaceflight environment; HRP's current understanding of that state with an indication of uncertainties; and how that state changes due to HRP programmatic progress and design reference mission definitions. In this talk, we will discuss proof-of-concept work performed using a subset of publications captured in the HRP publications database. The publications were tagged in the database with words representing factors influencing health and performance in spaceflight, as well as with words representing the risks HRP research is reducing. Analysis was performed on the publication tag data to identify relationships between factors and between risks. Network representations were then created as one type of visualization of these relationships. This enables future analyses of the structure of the networks based on results from network theory. Such analyses can provide insights into HRP's current human system knowledge state as informed by the publication data. The network structure analyses can also elucidate potential improvements by identifying network connections to establish or strengthen for maximized information flow. The relationships identified in the publication data were subsequently used as inputs to a model captured in the Systems Modeling Language (SysML), which functions as a repository for relationship information to be gleaned from multiple sources. Example network visualization outputs from a simple SysML model were then also created to compare to the visualizations based on the publication data only. We will also discuss ideas for building upon this proof-of-concept work to further support an integrated approach to human spaceflight risk reduction.

  13. Evaluating System Parameters on a Dragonfly using Simulation and Visualization

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bhatele, Abhinav; Jain, Nikhil; Livnat, Yarden

    The dragon y topology is becoming a popular choice for build- ing high-radix, low-diameter networks with high-bandwidth links. Even with a powerful network, preliminary experi- ments on Edison at NERSC have shown that for communica- tion heavy applications, job interference and thus presumably job placement remains an important factor. In this paper, we explore the e ects of job placement, job sizes, parallel workloads and network con gurations on network through- put to better understand inter-job interference. We use a simulation tool called Damsel y to model the network be- havior of Edison and study the impact of various systemmore » parameters on network throughput. Parallel workloads based on ve representative communication patters are used and the simulation studies on up to 131,072 cores are aided by a new visualization of the dragon y network.« less

  14. The Sander parallelogram illusion dissociates action and perception despite control for the litany of past confounds.

    PubMed

    Whitwell, Robert L; Goodale, Melvyn A; Merritt, Kate E; Enns, James T

    2018-01-01

    The two visual systems hypothesis proposes that human vision is supported by an occipito-temporal network for the conscious visual perception of the world and a fronto-parietal network for visually-guided, object-directed actions. Two specific claims about the fronto-parietal network's role in sensorimotor control have generated much data and controversy: (1) the network relies primarily on the absolute metrics of target objects, which it rapidly transforms into effector-specific frames of reference to guide the fingers, hands, and limbs, and (2) the network is largely unaffected by scene-based information extracted by the occipito-temporal network for those same targets. These two claims lead to the counter-intuitive prediction that in-flight anticipatory configuration of the fingers during object-directed grasping will resist the influence of pictorial illusions. The research confirming this prediction has been criticized for confounding the difference between grasping and explicit estimates of object size with differences in attention, sensory feedback, obstacle avoidance, metric sensitivity, and priming. Here, we address and eliminate each of these confounds. We asked participants to reach out and pick up 3D target bars resting on a picture of the Sander Parallelogram illusion and to make explicit estimates of the length of those bars. Participants performed their grasps without visual feedback, and were permitted to grasp the targets after making their size-estimates to afford them an opportunity to reduce illusory error with haptic feedback. The results show unequivocally that the effect of the illusion is stronger on perceptual judgments than on grasping. Our findings from the normally-sighted population provide strong support for the proposal that human vision is comprised of functionally and anatomically dissociable systems. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Rise and fall of the two visual systems theory.

    PubMed

    Rossetti, Yves; Pisella, Laure; McIntosh, Robert D

    2017-06-01

    Among the many dissociations describing the visual system, the dual theory of two visual systems, respectively dedicated to perception and action, has yielded a lot of support. There are psychophysical, anatomical and neuropsychological arguments in favor of this theory. Several behavioral studies that used sensory and motor psychophysical parameters observed differences between perceptive and motor responses. The anatomical network of the visual system in the non-human primate was very readily organized according to two major pathways, dorsal and ventral. Neuropsychological studies, exploring optic ataxia and visual agnosia as characteristic deficits of these two pathways, led to the proposal of a functional double dissociation between visuomotor and visual perceptual functions. After a major wave of popularity that promoted great advances, particularly in knowledge of visuomotor functions, the guiding theory is now being reconsidered. Firstly, the idea of a double dissociation between optic ataxia and visual form agnosia, as cleanly separating visuomotor from visual perceptual functions, is no longer tenable; optic ataxia does not support a dissociation between perception and action and might be more accurately viewed as a negative image of action blindsight. Secondly, dissociations between perceptive and motor responses highlighted in the framework of this theory concern a very elementary level of action, even automatically guided action routines. Thirdly, the very rich interconnected network of the visual brain yields few arguments in favor of a strict perception/action dissociation. Overall, the dissociation between motor function and perceptive function explored by these behavioral and neuropsychological studies can help define an automatic level of action organization deficient in optic ataxia and preserved in action blindsight, and underlines the renewed need to consider the perception-action circle as a functional ensemble. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  16. A Rotational Motion Perception Neural Network Based on Asymmetric Spatiotemporal Visual Information Processing.

    PubMed

    Hu, Bin; Yue, Shigang; Zhang, Zhuhong

    All complex motion patterns can be decomposed into several elements, including translation, expansion/contraction, and rotational motion. In biological vision systems, scientists have found that specific types of visual neurons have specific preferences to each of the three motion elements. There are computational models on translation and expansion/contraction perceptions; however, little has been done in the past to create computational models for rotational motion perception. To fill this gap, we proposed a neural network that utilizes a specific spatiotemporal arrangement of asymmetric lateral inhibited direction selective neural networks (DSNNs) for rotational motion perception. The proposed neural network consists of two parts-presynaptic and postsynaptic parts. In the presynaptic part, there are a number of lateral inhibited DSNNs to extract directional visual cues. In the postsynaptic part, similar to the arrangement of the directional columns in the cerebral cortex, these direction selective neurons are arranged in a cyclic order to perceive rotational motion cues. In the postsynaptic network, the delayed excitation from each direction selective neuron is multiplied by the gathered excitation from this neuron and its unilateral counterparts depending on which rotation, clockwise (cw) or counter-cw (ccw), to perceive. Systematic experiments under various conditions and settings have been carried out and validated the robustness and reliability of the proposed neural network in detecting cw or ccw rotational motion. This research is a critical step further toward dynamic visual information processing.All complex motion patterns can be decomposed into several elements, including translation, expansion/contraction, and rotational motion. In biological vision systems, scientists have found that specific types of visual neurons have specific preferences to each of the three motion elements. There are computational models on translation and expansion/contraction perceptions; however, little has been done in the past to create computational models for rotational motion perception. To fill this gap, we proposed a neural network that utilizes a specific spatiotemporal arrangement of asymmetric lateral inhibited direction selective neural networks (DSNNs) for rotational motion perception. The proposed neural network consists of two parts-presynaptic and postsynaptic parts. In the presynaptic part, there are a number of lateral inhibited DSNNs to extract directional visual cues. In the postsynaptic part, similar to the arrangement of the directional columns in the cerebral cortex, these direction selective neurons are arranged in a cyclic order to perceive rotational motion cues. In the postsynaptic network, the delayed excitation from each direction selective neuron is multiplied by the gathered excitation from this neuron and its unilateral counterparts depending on which rotation, clockwise (cw) or counter-cw (ccw), to perceive. Systematic experiments under various conditions and settings have been carried out and validated the robustness and reliability of the proposed neural network in detecting cw or ccw rotational motion. This research is a critical step further toward dynamic visual information processing.

  17. NaviCell Web Service for network-based data visualization.

    PubMed

    Bonnet, Eric; Viara, Eric; Kuperstein, Inna; Calzone, Laurence; Cohen, David P A; Barillot, Emmanuel; Zinovyev, Andrei

    2015-07-01

    Data visualization is an essential element of biological research, required for obtaining insights and formulating new hypotheses on mechanisms of health and disease. NaviCell Web Service is a tool for network-based visualization of 'omics' data which implements several data visual representation methods and utilities for combining them together. NaviCell Web Service uses Google Maps and semantic zooming to browse large biological network maps, represented in various formats, together with different types of the molecular data mapped on top of them. For achieving this, the tool provides standard heatmaps, barplots and glyphs as well as the novel map staining technique for grasping large-scale trends in numerical values (such as whole transcriptome) projected onto a pathway map. The web service provides a server mode, which allows automating visualization tasks and retrieving data from maps via RESTful (standard HTTP) calls. Bindings to different programming languages are provided (Python and R). We illustrate the purpose of the tool with several case studies using pathway maps created by different research groups, in which data visualization provides new insights into molecular mechanisms involved in systemic diseases such as cancer and neurodegenerative diseases. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  18. NaviCell Web Service for network-based data visualization

    PubMed Central

    Bonnet, Eric; Viara, Eric; Kuperstein, Inna; Calzone, Laurence; Cohen, David P. A.; Barillot, Emmanuel; Zinovyev, Andrei

    2015-01-01

    Data visualization is an essential element of biological research, required for obtaining insights and formulating new hypotheses on mechanisms of health and disease. NaviCell Web Service is a tool for network-based visualization of ‘omics’ data which implements several data visual representation methods and utilities for combining them together. NaviCell Web Service uses Google Maps and semantic zooming to browse large biological network maps, represented in various formats, together with different types of the molecular data mapped on top of them. For achieving this, the tool provides standard heatmaps, barplots and glyphs as well as the novel map staining technique for grasping large-scale trends in numerical values (such as whole transcriptome) projected onto a pathway map. The web service provides a server mode, which allows automating visualization tasks and retrieving data from maps via RESTful (standard HTTP) calls. Bindings to different programming languages are provided (Python and R). We illustrate the purpose of the tool with several case studies using pathway maps created by different research groups, in which data visualization provides new insights into molecular mechanisms involved in systemic diseases such as cancer and neurodegenerative diseases. PMID:25958393

  19. Dynamic Visualization of Co-expression in Systems Genetics Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    New, Joshua Ryan; Huang, Jian; Chesler, Elissa J

    2008-01-01

    Biologists hope to address grand scientific challenges by exploring the abundance of data made available through modern microarray technology and other high-throughput techniques. The impact of this data, however, is limited unless researchers can effectively assimilate such complex information and integrate it into their daily research; interactive visualization tools are called for to support the effort. Specifically, typical studies of gene co-expression require novel visualization tools that enable the dynamic formulation and fine-tuning of hypotheses to aid the process of evaluating sensitivity of key parameters. These tools should allow biologists to develop an intuitive understanding of the structure of biologicalmore » networks and discover genes which reside in critical positions in networks and pathways. By using a graph as a universal data representation of correlation in gene expression data, our novel visualization tool employs several techniques that when used in an integrated manner provide innovative analytical capabilities. Our tool for interacting with gene co-expression data integrates techniques such as: graph layout, qualitative subgraph extraction through a novel 2D user interface, quantitative subgraph extraction using graph-theoretic algorithms or by querying an optimized b-tree, dynamic level-of-detail graph abstraction, and template-based fuzzy classification using neural networks. We demonstrate our system using a real-world workflow from a large-scale, systems genetics study of mammalian gene co-expression.« less

  20. Bridging the Gap between Physiology and Behavior: Evidence from the sSoTS Model of Human Visual Attention

    ERIC Educational Resources Information Center

    Mavritsaki, Eirini; Heinke, Dietmar; Allen, Harriet; Deco, Gustavo; Humphreys, Glyn W.

    2011-01-01

    We present the case for a role of biologically plausible neural network modeling in bridging the gap between physiology and behavior. We argue that spiking-level networks can allow "vertical" translation between physiological properties of neural systems and emergent "whole-system" performance--enabling psychological results to be simulated from…

  1. Automatic delineation and 3D visualization of the human ventricular system using probabilistic neural networks

    NASA Astrophysics Data System (ADS)

    Hatfield, Fraser N.; Dehmeshki, Jamshid

    1998-09-01

    Neurosurgery is an extremely specialized area of medical practice, requiring many years of training. It has been suggested that virtual reality models of the complex structures within the brain may aid in the training of neurosurgeons as well as playing an important role in the preparation for surgery. This paper focuses on the application of a probabilistic neural network to the automatic segmentation of the ventricles from magnetic resonance images of the brain, and their three dimensional visualization.

  2. JPL Earth Science Center Visualization Multitouch Table

    NASA Astrophysics Data System (ADS)

    Kim, R.; Dodge, K.; Malhotra, S.; Chang, G.

    2014-12-01

    JPL Earth Science Center Visualization table is a specialized software and hardware to allow multitouch, multiuser, and remote display control to create seamlessly integrated experiences to visualize JPL missions and their remote sensing data. The software is fully GIS capable through time aware OGC WMTS using Lunar Mapping and Modeling Portal as the GIS backend to continuously ingest and retrieve realtime remote sending data and satellite location data. 55 inch and 82 inch unlimited finger count multitouch displays allows multiple users to explore JPL Earth missions and visualize remote sensing data through very intuitive and interactive touch graphical user interface. To improve the integrated experience, Earth Science Center Visualization Table team developed network streaming which allows table software to stream data visualization to near by remote display though computer network. The purpose of this visualization/presentation tool is not only to support earth science operation, but specifically designed for education and public outreach and will significantly contribute to STEM. Our presentation will include overview of our software, hardware, and showcase of our system.

  3. Visualizing Mobility of Public Transportation System.

    PubMed

    Zeng, Wei; Fu, Chi-Wing; Arisona, Stefan Müller; Erath, Alexander; Qu, Huamin

    2014-12-01

    Public transportation systems (PTSs) play an important role in modern cities, providing shared/massive transportation services that are essential for the general public. However, due to their increasing complexity, designing effective methods to visualize and explore PTS is highly challenging. Most existing techniques employ network visualization methods and focus on showing the network topology across stops while ignoring various mobility-related factors such as riding time, transfer time, waiting time, and round-the-clock patterns. This work aims to visualize and explore passenger mobility in a PTS with a family of analytical tasks based on inputs from transportation researchers. After exploring different design alternatives, we come up with an integrated solution with three visualization modules: isochrone map view for geographical information, isotime flow map view for effective temporal information comparison and manipulation, and OD-pair journey view for detailed visual analysis of mobility factors along routes between specific origin-destination pairs. The isotime flow map linearizes a flow map into a parallel isoline representation, maximizing the visualization of mobility information along the horizontal time axis while presenting clear and smooth pathways from origin to destinations. Moreover, we devise several interactive visual query methods for users to easily explore the dynamics of PTS mobility over space and time. Lastly, we also construct a PTS mobility model from millions of real passenger trajectories, and evaluate our visualization techniques with assorted case studies with the transportation researchers.

  4. Occipital cortical thickness in very low birth weight born adolescents predicts altered neural specialization of visual semantic category related neural networks.

    PubMed

    Klaver, Peter; Latal, Beatrice; Martin, Ernst

    2015-01-01

    Very low birth weight (VLBW) premature born infants have a high risk to develop visual perceptual and learning deficits as well as widespread functional and structural brain abnormalities during infancy and childhood. Whether and how prematurity alters neural specialization within visual neural networks is still unknown. We used functional and structural brain imaging to examine the visual semantic system of VLBW born (<1250 g, gestational age 25-32 weeks) adolescents (13-15 years, n = 11, 3 males) and matched term born control participants (13-15 years, n = 11, 3 males). Neurocognitive assessment revealed no group differences except for lower scores on an adaptive visuomotor integration test. All adolescents were scanned while viewing pictures of animals and tools and scrambled versions of these pictures. Both groups demonstrated animal and tool category related neural networks. Term born adolescents showed tool category related neural activity, i.e. tool pictures elicited more activity than animal pictures, in temporal and parietal brain areas. Animal category related activity was found in the occipital, temporal and frontal cortex. VLBW born adolescents showed reduced tool category related activity in the dorsal visual stream compared with controls, specifically the left anterior intraparietal sulcus, and enhanced animal category related activity in the left middle occipital gyrus and right lingual gyrus. Lower birth weight of VLBW adolescents correlated with larger thickness of the pericalcarine gyrus in the occipital cortex and smaller surface area of the superior temporal gyrus in the lateral temporal cortex. Moreover, larger thickness of the pericalcarine gyrus and smaller surface area of the superior temporal gyrus correlated with reduced tool category related activity in the parietal cortex. Together, our data suggest that very low birth weight predicts alterations of higher order visual semantic networks, particularly in the dorsal stream. The differences in neural specialization may be associated with aberrant cortical development of areas in the visual system that develop early in childhood. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. Study of Tools for Network Discovery and Network Mapping

    DTIC Science & Technology

    2003-11-01

    connected to the switch. iv. Accessibility of historical data and event data In general, network discovery tools keep a history of the collected...has the following software dependencies: - Java Virtual machine 76 - Perl modules - RRD Tool - TomCat - PostgreSQL STRENGTHS AND...systems - provide a simple view of the current network status - generate alarms on status change - generate history of status change VISUAL MAP

  6. Simultaneous Visualization of Different Utility Networks for Disaster Management

    NASA Astrophysics Data System (ADS)

    Semm, S.; Becker, T.; Kolbe, T. H.

    2012-07-01

    Cartographic visualizations of crises are used to create a Common Operational Picture (COP) and enforce Situational Awareness by presenting and representing relevant information. As nearly all crises affect geospatial entities, geo-data representations have to support location-specific decision-making throughout the crises. Since, Operator's attention span and their working memory are limiting factors for the process of getting and interpreting information; the cartographic presentation has to support individuals in coordinating their activities and with handling highly dynamic situations. The Situational Awareness of operators in conjunction with a COP are key aspects of the decision making process and essential for coming to appropriate decisions. Utility networks are one of the most complex and most needed systems within a city. The visualization of utility infrastructure in crisis situations is addressed in this paper. The paper will provide a conceptual approach on how to simplify, aggregate, and visualize multiple utility networks and their components to meet the requirements of the decision-making process and to support Situational Awareness.

  7. Dynamic Interactions for Network Visualization and Simulation

    DTIC Science & Technology

    2009-03-01

    projects.htm, Site accessed January 5, 2009. 12. John S. Weir, Major, USAF, Mediated User-Simulator Interactive Command with Visualization ( MUSIC -V). Master’s...Computing Sciences in Colleges, December 2005). 14. Enrique Campos -Nanez, “nscript user manual,” Department of System Engineer- ing University of

  8. Biographer: web-based editing and rendering of SBGN compliant biochemical networks

    PubMed Central

    Krause, Falko; Schulz, Marvin; Ripkens, Ben; Flöttmann, Max; Krantz, Marcus; Klipp, Edda; Handorf, Thomas

    2013-01-01

    Motivation: The rapid accumulation of knowledge in the field of Systems Biology during the past years requires advanced, but simple-to-use, methods for the visualization of information in a structured and easily comprehensible manner. Results: We have developed biographer, a web-based renderer and editor for reaction networks, which can be integrated as a library into tools dealing with network-related information. Our software enables visualizations based on the emerging standard Systems Biology Graphical Notation. It is able to import networks encoded in various formats such as SBML, SBGN-ML and jSBGN, a custom lightweight exchange format. The core package is implemented in HTML5, CSS and JavaScript and can be used within any kind of web-based project. It features interactive graph-editing tools and automatic graph layout algorithms. In addition, we provide a standalone graph editor and a web server, which contains enhanced features like web services for the import and export of models and visualizations in different formats. Availability: The biographer tool can be used at and downloaded from the web page http://biographer.biologie.hu-berlin.de/. The different software packages, including a server-indepenent version as well as a web server for Windows and Linux based systems, are available at http://code.google.com/p/biographer/ under the open-source license LGPL. Contact: edda.klipp@biologie.hu-berlin.de or handorf@physik.hu-berlin.de PMID:23574737

  9. Availability Issues in Wireless Visual Sensor Networks

    PubMed Central

    Costa, Daniel G.; Silva, Ivanovitch; Guedes, Luiz Affonso; Vasques, Francisco; Portugal, Paulo

    2014-01-01

    Wireless visual sensor networks have been considered for a large set of monitoring applications related with surveillance, tracking and multipurpose visual monitoring. When sensors are deployed over a monitored field, permanent faults may happen during the network lifetime, reducing the monitoring quality or rendering parts or the entire network unavailable. In a different way from scalar sensor networks, camera-enabled sensors collect information following a directional sensing model, which changes the notions of vicinity and redundancy. Moreover, visual source nodes may have different relevancies for the applications, according to the monitoring requirements and cameras' poses. In this paper we discuss the most relevant availability issues related to wireless visual sensor networks, addressing availability evaluation and enhancement. Such discussions are valuable when designing, deploying and managing wireless visual sensor networks, bringing significant contributions to these networks. PMID:24526301

  10. Public Health Analysis Transport Optimization Model v. 1.0

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Beyeler, Walt; Finley, Patrick; Walser, Alex

    PHANTOM models logistic functions of national public health systems. The system enables public health officials to visualize and coordinate options for public health surveillance, diagnosis, response and administration in an integrated analytical environment. Users may simulate and analyze system performance applying scenarios that represent current conditions or future contingencies what-if analyses of potential systemic improvements. Public health networks are visualized as interactive maps, with graphical displays of relevant system performance metrics as calculated by the simulation modeling components.

  11. Impulse processing: A dynamical systems model of incremental eye movements in the visual world paradigm

    PubMed Central

    Kukona, Anuenue; Tabor, Whitney

    2011-01-01

    The visual world paradigm presents listeners with a challenging problem: they must integrate two disparate signals, the spoken language and the visual context, in support of action (e.g., complex movements of the eyes across a scene). We present Impulse Processing, a dynamical systems approach to incremental eye movements in the visual world that suggests a framework for integrating language, vision, and action generally. Our approach assumes that impulses driven by the language and the visual context impinge minutely on a dynamical landscape of attractors corresponding to the potential eye-movement behaviors of the system. We test three unique predictions of our approach in an empirical study in the visual world paradigm, and describe an implementation in an artificial neural network. We discuss the Impulse Processing framework in relation to other models of the visual world paradigm. PMID:21609355

  12. System Access | High-Performance Computing | NREL

    Science.gov Websites

    ) systems. Photo of man looking at a large computer monitor with a colorful, visual display of data. System secure shell gateway (SSH) or virtual private network (VPN). User Accounts Request a user account

  13. Envision: An interactive system for the management and visualization of large geophysical data sets

    NASA Technical Reports Server (NTRS)

    Searight, K. R.; Wojtowicz, D. P.; Walsh, J. E.; Pathi, S.; Bowman, K. P.; Wilhelmson, R. B.

    1995-01-01

    Envision is a software project at the University of Illinois and Texas A&M, funded by NASA's Applied Information Systems Research Project. It provides researchers in the geophysical sciences convenient ways to manage, browse, and visualize large observed or model data sets. Envision integrates data management, analysis, and visualization of geophysical data in an interactive environment. It employs commonly used standards in data formats, operating systems, networking, and graphics. It also attempts, wherever possible, to integrate with existing scientific visualization and analysis software. Envision has an easy-to-use graphical interface, distributed process components, and an extensible design. It is a public domain package, freely available to the scientific community.

  14. Visualization of protein interaction networks: problems and solutions

    PubMed Central

    2013-01-01

    Background Visualization concerns the representation of data visually and is an important task in scientific research. Protein-protein interactions (PPI) are discovered using either wet lab techniques, such mass spectrometry, or in silico predictions tools, resulting in large collections of interactions stored in specialized databases. The set of all interactions of an organism forms a protein-protein interaction network (PIN) and is an important tool for studying the behaviour of the cell machinery. Since graphic representation of PINs may highlight important substructures, e.g. protein complexes, visualization is more and more used to study the underlying graph structure of PINs. Although graphs are well known data structures, there are different open problems regarding PINs visualization: the high number of nodes and connections, the heterogeneity of nodes (proteins) and edges (interactions), the possibility to annotate proteins and interactions with biological information extracted by ontologies (e.g. Gene Ontology) that enriches the PINs with semantic information, but complicates their visualization. Methods In these last years many software tools for the visualization of PINs have been developed. Initially thought for visualization only, some of them have been successively enriched with new functions for PPI data management and PIN analysis. The paper analyzes the main software tools for PINs visualization considering four main criteria: (i) technology, i.e. availability/license of the software and supported OS (Operating System) platforms; (ii) interoperability, i.e. ability to import/export networks in various formats, ability to export data in a graphic format, extensibility of the system, e.g. through plug-ins; (iii) visualization, i.e. supported layout and rendering algorithms and availability of parallel implementation; (iv) analysis, i.e. availability of network analysis functions, such as clustering or mining of the graph, and the possibility to interact with external databases. Results Currently, many tools are available and it is not easy for the users choosing one of them. Some tools offer sophisticated 2D and 3D network visualization making available many layout algorithms, others tools are more data-oriented and support integration of interaction data coming from different sources and data annotation. Finally, some specialistic tools are dedicated to the analysis of pathways and cellular processes and are oriented toward systems biology studies, where the dynamic aspects of the processes being studied are central. Conclusion A current trend is the deployment of open, extensible visualization tools (e.g. Cytoscape), that may be incrementally enriched by the interactomics community with novel and more powerful functions for PIN analysis, through the development of plug-ins. On the other hand, another emerging trend regards the efficient and parallel implementation of the visualization engine that may provide high interactivity and near real-time response time, as in NAViGaTOR. From a technological point of view, open-source, free and extensible tools, like Cytoscape, guarantee a long term sustainability due to the largeness of the developers and users communities, and provide a great flexibility since new functions are continuously added by the developer community through new plug-ins, but the emerging parallel, often closed-source tools like NAViGaTOR, can offer near real-time response time also in the analysis of very huge PINs. PMID:23368786

  15. Neural nets for aligning optical components in harsh environments: Beam smoothing spatial filter as an example

    NASA Technical Reports Server (NTRS)

    Decker, Arthur J.; Krasowski, Michael J.

    1991-01-01

    The goal is to develop an approach to automating the alignment and adjustment of optical measurement, visualization, inspection, and control systems. Classical controls, expert systems, and neural networks are three approaches to automating the alignment of an optical system. Neural networks were chosen for this project and the judgements that led to this decision are presented. Neural networks were used to automate the alignment of the ubiquitous laser-beam-smoothing spatial filter. The results and future plans of the project are presented.

  16. A Supramodal Neural Network for Speech and Gesture Semantics: An fMRI Study

    PubMed Central

    Weis, Susanne; Kircher, Tilo

    2012-01-01

    In a natural setting, speech is often accompanied by gestures. As language, speech-accompanying iconic gestures to some extent convey semantic information. However, if comprehension of the information contained in both the auditory and visual modality depends on same or different brain-networks is quite unknown. In this fMRI study, we aimed at identifying the cortical areas engaged in supramodal processing of semantic information. BOLD changes were recorded in 18 healthy right-handed male subjects watching video clips showing an actor who either performed speech (S, acoustic) or gestures (G, visual) in more (+) or less (−) meaningful varieties. In the experimental conditions familiar speech or isolated iconic gestures were presented; during the visual control condition the volunteers watched meaningless gestures (G−), while during the acoustic control condition a foreign language was presented (S−). The conjunction of the visual and acoustic semantic processing revealed activations extending from the left inferior frontal gyrus to the precentral gyrus, and included bilateral posterior temporal regions. We conclude that proclaiming this frontotemporal network the brain's core language system is to take too narrow a view. Our results rather indicate that these regions constitute a supramodal semantic processing network. PMID:23226488

  17. OCT-based angiography in real time with hand-held probe

    NASA Astrophysics Data System (ADS)

    Gelikonov, Grigory V.; Moiseev, Alexander A.; Ksenofontov, Sergey Y.; Terpelov, Dmitry A.; Gelikonov, Valentine M.

    2018-03-01

    This work is dedicated to development of the OCT system capable to visualize blood vessel network for everyday clinical use. Following problems were solved during the development: compensation of specific natural tissue displacements, induced by contact scanning mode and physiological motion of patients (e.g. respiratory and cardiac motions) and on-line visualization of vessel net to provide the feedback for system operator.

  18. Emotion Separation Is Completed Early and It Depends on Visual Field Presentation

    PubMed Central

    Liu, Lichan; Ioannides, Andreas A.

    2010-01-01

    It is now apparent that the visual system reacts to stimuli very fast, with many brain areas activated within 100 ms. It is, however, unclear how much detail is extracted about stimulus properties in the early stages of visual processing. Here, using magnetoencephalography we show that the visual system separates different facial expressions of emotion well within 100 ms after image onset, and that this separation is processed differently depending on where in the visual field the stimulus is presented. Seven right-handed males participated in a face affect recognition experiment in which they viewed happy, fearful and neutral faces. Blocks of images were shown either at the center or in one of the four quadrants of the visual field. For centrally presented faces, the emotions were separated fast, first in the right superior temporal sulcus (STS; 35–48 ms), followed by the right amygdala (57–64 ms) and medial pre-frontal cortex (83–96 ms). For faces presented in the periphery, the emotions were separated first in the ipsilateral amygdala and contralateral STS. We conclude that amygdala and STS likely play a different role in early visual processing, recruiting distinct neural networks for action: the amygdala alerts sub-cortical centers for appropriate autonomic system response for fight or flight decisions, while the STS facilitates more cognitive appraisal of situations and links appropriate cortical sites together. It is then likely that different problems may arise when either network fails to initiate or function properly. PMID:20339549

  19. GeoBuilder: a geometric algorithm visualization and debugging system for 2D and 3D geometric computing.

    PubMed

    Wei, Jyh-Da; Tsai, Ming-Hung; Lee, Gen-Cher; Huang, Jeng-Hung; Lee, Der-Tsai

    2009-01-01

    Algorithm visualization is a unique research topic that integrates engineering skills such as computer graphics, system programming, database management, computer networks, etc., to facilitate algorithmic researchers in testing their ideas, demonstrating new findings, and teaching algorithm design in the classroom. Within the broad applications of algorithm visualization, there still remain performance issues that deserve further research, e.g., system portability, collaboration capability, and animation effect in 3D environments. Using modern technologies of Java programming, we develop an algorithm visualization and debugging system, dubbed GeoBuilder, for geometric computing. The GeoBuilder system features Java's promising portability, engagement of collaboration in algorithm development, and automatic camera positioning for tracking 3D geometric objects. In this paper, we describe the design of the GeoBuilder system and demonstrate its applications.

  20. Expanded DEMATEL for Determining Cause and Effect Group in Bidirectional Relations

    PubMed Central

    Falatoonitoosi, Elham; Ahmed, Shamsuddin; Sorooshian, Shahryar

    2014-01-01

    Decision-Making Trial and Evaluation Laboratory (DEMATEL) methodology has been proposed to solve complex and intertwined problem groups in many situations such as developing the capabilities, complex group decision making, security problems, marketing approaches, global managers, and control systems. DEMATEL is able to realize casual relationships by dividing important issues into cause and effect group as well as making it possible to visualize the casual relationships of subcriteria and systems in the course of casual diagram that it may demonstrate communication network or a little control relationships between individuals. Despite of its ability to visualize cause and effect inside a network, the original DEMATEL has not been able to find the cause and effect group between different networks. Therefore, the aim of this study is proposing the expanded DEMATEL to cover this deficiency by new formulations to determine cause and effect factors between separate networks that have bidirectional direct impact on each other. At the end, the feasibility of new extra formulations is validated by case study in three numerical examples of green supply chain networks for an automotive company. PMID:24693224

  1. Expanded DEMATEL for determining cause and effect group in bidirectional relations.

    PubMed

    Falatoonitoosi, Elham; Ahmed, Shamsuddin; Sorooshian, Shahryar

    2014-01-01

    Decision-Making Trial and Evaluation Laboratory (DEMATEL) methodology has been proposed to solve complex and intertwined problem groups in many situations such as developing the capabilities, complex group decision making, security problems, marketing approaches, global managers, and control systems. DEMATEL is able to realize casual relationships by dividing important issues into cause and effect group as well as making it possible to visualize the casual relationships of subcriteria and systems in the course of casual diagram that it may demonstrate communication network or a little control relationships between individuals. Despite of its ability to visualize cause and effect inside a network, the original DEMATEL has not been able to find the cause and effect group between different networks. Therefore, the aim of this study is proposing the expanded DEMATEL to cover this deficiency by new formulations to determine cause and effect factors between separate networks that have bidirectional direct impact on each other. At the end, the feasibility of new extra formulations is validated by case study in three numerical examples of green supply chain networks for an automotive company.

  2. Abnormal brain activation in neurofibromatosis type 1: a link between visual processing and the default mode network.

    PubMed

    Violante, Inês R; Ribeiro, Maria J; Cunha, Gil; Bernardino, Inês; Duarte, João V; Ramos, Fabiana; Saraiva, Jorge; Silva, Eduardo; Castelo-Branco, Miguel

    2012-01-01

    Neurofibromatosis type 1 (NF1) is one of the most common single gene disorders affecting the human nervous system with a high incidence of cognitive deficits, particularly visuospatial. Nevertheless, neurophysiological alterations in low-level visual processing that could be relevant to explain the cognitive phenotype are poorly understood. Here we used functional magnetic resonance imaging (fMRI) to study early cortical visual pathways in children and adults with NF1. We employed two distinct stimulus types differing in contrast and spatial and temporal frequencies to evoke relatively different activation of the magnocellular (M) and parvocellular (P) pathways. Hemodynamic responses were investigated in retinotopically-defined regions V1, V2 and V3 and then over the acquired cortical volume. Relative to matched control subjects, patients with NF1 showed deficient activation of the low-level visual cortex to both stimulus types. Importantly, this finding was observed for children and adults with NF1, indicating that low-level visual processing deficits do not ameliorate with age. Moreover, only during M-biased stimulation patients with NF1 failed to deactivate or even activated anterior and posterior midline regions of the default mode network. The observation that the magnocellular visual pathway is impaired in NF1 in early visual processing and is specifically associated with a deficient deactivation of the default mode network may provide a neural explanation for high-order cognitive deficits present in NF1, particularly visuospatial and attentional. A link between magnocellular and default mode network processing may generalize to neuropsychiatric disorders where such deficits have been separately identified.

  3. Patterns of resting state connectivity in human primary visual cortical areas: a 7T fMRI study.

    PubMed

    Raemaekers, Mathijs; Schellekens, Wouter; van Wezel, Richard J A; Petridou, Natalia; Kristo, Gert; Ramsey, Nick F

    2014-01-01

    The nature and origin of fMRI resting state fluctuations and connectivity are still not fully known. More detailed knowledge on the relationship between resting state patterns and brain function may help to elucidate this matter. We therefore performed an in depth study of how resting state fluctuations map to the well known architecture of the visual system. We investigated resting state connectivity at both a fine and large scale within and across visual areas V1, V2 and V3 in ten human subjects using a 7Tesla scanner. We found evidence for several coexisting and overlapping connectivity structures at different spatial scales. At the fine-scale level we found enhanced connectivity between the same topographic locations in the fieldmaps of V1, V2 and V3, enhanced connectivity to the contralateral functional homologue, and to a lesser extent enhanced connectivity between iso-eccentric locations within the same visual area. However, by far the largest proportion of the resting state fluctuations occurred within large-scale bilateral networks. These large-scale networks mapped to some extent onto the architecture of the visual system and could thereby obscure fine-scale connectivity. In fact, most of the fine-scale connectivity only became apparent after the large-scale network fluctuations were filtered from the timeseries. We conclude that fMRI resting state fluctuations in the visual cortex may in fact be a composite signal of different overlapping sources. Isolating the different sources could enhance correlations between BOLD and electrophysiological correlates of resting state activity. © 2013 Elsevier Inc. All rights reserved.

  4. Hierarchical neural network model of the visual system determining figure/ground relation

    NASA Astrophysics Data System (ADS)

    Kikuchi, Masayuki

    2017-07-01

    One of the most important functions of the visual perception in the brain is figure/ground interpretation from input images. Figural region in 2D image corresponding to object in 3D space are distinguished from background region extended behind the object. Previously the author proposed a neural network model of figure/ground separation constructed on the standpoint that local geometric features such as curvatures and outer angles at corners are extracted and propagated along input contour in a single layer network (Kikuchi & Akashi, 2001). However, such a processing principle has the defect that signal propagation requires manyiterations despite the fact that actual visual system determines figure/ground relation within the short period (Zhou et al., 2000). In order to attain speed-up for determining figure/ground, this study incorporates hierarchical architecture into the previous model. This study confirmed the effect of the hierarchization as for the computation time by simulation. As the number of layers increased, the required computation time reduced. However, such speed-up effect was saturatedas the layers increased to some extent. This study attempted to explain this saturation effect by the notion of average distance between vertices in the area of complex network, and succeeded to mimic the saturation effect by computer simulation.

  5. IEEE Conference on Neural Information Processing Systems - Natural and Synthetic Held in Denver, Colorado on 28 November-1 December 1988

    DTIC Science & Technology

    1989-08-14

    DISCRIMINATE SIMILAR KANJt CHARACTERS. Yoshihiro Mori, Kazuhiko Yokosawa . 12 FURTHER EXPLORATIONS IN THE LEARNING OF VISUALLY-GUIDED REACHING: MAKING MURPHY...NETWORKS THAT LEARN TO DISCRIMINATE SIMILAR KANJI CHARACTERS YOSHIHIRO MORI, KAZUHIKO YOKOSAWA , ATR Auditory and Visual Perception Research Laboratories

  6. Adaptation to sensory input tunes visual cortex to criticality

    NASA Astrophysics Data System (ADS)

    Shew, Woodrow L.; Clawson, Wesley P.; Pobst, Jeff; Karimipanah, Yahya; Wright, Nathaniel C.; Wessel, Ralf

    2015-08-01

    A long-standing hypothesis at the interface of physics and neuroscience is that neural networks self-organize to the critical point of a phase transition, thereby optimizing aspects of sensory information processing. This idea is partially supported by strong evidence for critical dynamics observed in the cerebral cortex, but the impact of sensory input on these dynamics is largely unknown. Thus, the foundations of this hypothesis--the self-organization process and how it manifests during strong sensory input--remain unstudied experimentally. Here we show in visual cortex and in a computational model that strong sensory input initially elicits cortical network dynamics that are not critical, but adaptive changes in the network rapidly tune the system to criticality. This conclusion is based on observations of multifaceted scaling laws predicted to occur at criticality. Our findings establish sensory adaptation as a self-organizing mechanism that maintains criticality in visual cortex during sensory information processing.

  7. [Automated anesthesia record system].

    PubMed

    Zhu, Tao; Liu, Jin

    2005-12-01

    Based on Client/Server architecture, a software of automated anesthesia record system running under Windows operation system and networks has been developed and programmed with Microsoft Visual C++ 6.0, Visual Basic 6.0 and SQL Server. The system can deal with patient's information throughout the anesthesia. It can collect and integrate the data from several kinds of medical equipment such as monitor, infusion pump and anesthesia machine automatically and real-time. After that, the system presents the anesthesia sheets automatically. The record system makes the anesthesia record more accurate and integral and can raise the anesthesiologist's working efficiency.

  8. Neural network based visualization of collaborations in a citizen science project

    NASA Astrophysics Data System (ADS)

    Morais, Alessandra M. M.; Santos, Rafael D. C.; Raddick, M. Jordan

    2014-05-01

    Citizen science projects are those in which volunteers are asked to collaborate in scientific projects, usually by volunteering idle computer time for distributed data processing efforts or by actively labeling or classifying information - shapes of galaxies, whale sounds, historical records are all examples of citizen science projects in which users access a data collecting system to label or classify images and sounds. In order to be successful, a citizen science project must captivate users and keep them interested on the project and on the science behind it, increasing therefore the time the users spend collaborating with the project. Understanding behavior of citizen scientists and their interaction with the data collection systems may help increase the involvement of the users, categorize them accordingly to different parameters, facilitate their collaboration with the systems, design better user interfaces, and allow better planning and deployment of similar projects and systems. Users behavior can be actively monitored or derived from their interaction with the data collection systems. Records of the interactions can be analyzed using visualization techniques to identify patterns and outliers. In this paper we present some results on the visualization of more than 80 million interactions of almost 150 thousand users with the Galaxy Zoo I citizen science project. Visualization of the attributes extracted from their behaviors was done with a clustering neural network (the Self-Organizing Map) and a selection of icon- and pixel-based techniques. These techniques allows the visual identification of groups of similar behavior in several different ways.

  9. Neural associative memories for the integration of language, vision and action in an autonomous agent.

    PubMed

    Markert, H; Kaufmann, U; Kara Kayikci, Z; Palm, G

    2009-03-01

    Language understanding is a long-standing problem in computer science. However, the human brain is capable of processing complex languages with seemingly no difficulties. This paper shows a model for language understanding using biologically plausible neural networks composed of associative memories. The model is able to deal with ambiguities on the single word and grammatical level. The language system is embedded into a robot in order to demonstrate the correct semantical understanding of the input sentences by letting the robot perform corresponding actions. For that purpose, a simple neural action planning system has been combined with neural networks for visual object recognition and visual attention control mechanisms.

  10. Supporting performance and configuration management of GTE cellular networks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tan, Ming; Lafond, C.; Jakobson, G.

    GTE Laboratories, in cooperation with GTE Mobilnet, has developed and deployed PERFFEX (PERFormance Expert), an intelligent system for performance and configuration management of cellular networks. PERFEX assists cellular network performance and radio engineers in the analysis of large volumes of cellular network performance and configuration data. It helps them locate and determine the probable causes of performance problems, and provides intelligent suggestions about how to correct them. The system combines an expert cellular network performance tuning capability with a map-based graphical user interface, data visualization programs, and a set of special cellular engineering tools. PERFEX is in daily use atmore » more than 25 GTE Mobile Switching Centers. Since the first deployment of the system in late 1993, PERFEX has become a major GTE cellular network performance optimization tool.« less

  11. Motor imagery learning modulates functional connectivity of multiple brain systems in resting state.

    PubMed

    Zhang, Hang; Long, Zhiying; Ge, Ruiyang; Xu, Lele; Jin, Zhen; Yao, Li; Liu, Yijun

    2014-01-01

    Learning motor skills involves subsequent modulation of resting-state functional connectivity in the sensory-motor system. This idea was mostly derived from the investigations on motor execution learning which mainly recruits the processing of sensory-motor information. Behavioral evidences demonstrated that motor skills in our daily lives could be learned through imagery procedures. However, it remains unclear whether the modulation of resting-state functional connectivity also exists in the sensory-motor system after motor imagery learning. We performed a fMRI investigation on motor imagery learning from resting state. Based on previous studies, we identified eight sensory and cognitive resting-state networks (RSNs) corresponding to the brain systems and further explored the functional connectivity of these RSNs through the assessments, connectivity and network strengths before and after the two-week consecutive learning. Two intriguing results were revealed: (1) The sensory RSNs, specifically sensory-motor and lateral visual networks exhibited greater connectivity strengths in precuneus and fusiform gyrus after learning; (2) Decreased network strength induced by learning was proved in the default mode network, a cognitive RSN. These results indicated that resting-state functional connectivity could be modulated by motor imagery learning in multiple brain systems, and such modulation displayed in the sensory-motor, visual and default brain systems may be associated with the establishment of motor schema and the regulation of introspective thought. These findings further revealed the neural substrates underlying motor skill learning and potentially provided new insights into the therapeutic benefits of motor imagery learning.

  12. An interactive web-based system using cloud for large-scale visual analytics

    NASA Astrophysics Data System (ADS)

    Kaseb, Ahmed S.; Berry, Everett; Rozolis, Erik; McNulty, Kyle; Bontrager, Seth; Koh, Youngsol; Lu, Yung-Hsiang; Delp, Edward J.

    2015-03-01

    Network cameras have been growing rapidly in recent years. Thousands of public network cameras provide tremendous amount of visual information about the environment. There is a need to analyze this valuable information for a better understanding of the world around us. This paper presents an interactive web-based system that enables users to execute image analysis and computer vision techniques on a large scale to analyze the data from more than 65,000 worldwide cameras. This paper focuses on how to use both the system's website and Application Programming Interface (API). Given a computer program that analyzes a single frame, the user needs to make only slight changes to the existing program and choose the cameras to analyze. The system handles the heterogeneity of the geographically distributed cameras, e.g. different brands, resolutions. The system allocates and manages Amazon EC2 and Windows Azure cloud resources to meet the analysis requirements.

  13. MONGKIE: an integrated tool for network analysis and visualization for multi-omics data.

    PubMed

    Jang, Yeongjun; Yu, Namhee; Seo, Jihae; Kim, Sun; Lee, Sanghyuk

    2016-03-18

    Network-based integrative analysis is a powerful technique for extracting biological insights from multilayered omics data such as somatic mutations, copy number variations, and gene expression data. However, integrated analysis of multi-omics data is quite complicated and can hardly be done in an automated way. Thus, a powerful interactive visual mining tool supporting diverse analysis algorithms for identification of driver genes and regulatory modules is much needed. Here, we present a software platform that integrates network visualization with omics data analysis tools seamlessly. The visualization unit supports various options for displaying multi-omics data as well as unique network models for describing sophisticated biological networks such as complex biomolecular reactions. In addition, we implemented diverse in-house algorithms for network analysis including network clustering and over-representation analysis. Novel functions include facile definition and optimized visualization of subgroups, comparison of a series of data sets in an identical network by data-to-visual mapping and subsequent overlaying function, and management of custom interaction networks. Utility of MONGKIE for network-based visual data mining of multi-omics data was demonstrated by analysis of the TCGA glioblastoma data. MONGKIE was developed in Java based on the NetBeans plugin architecture, thus being OS-independent with intrinsic support of module extension by third-party developers. We believe that MONGKIE would be a valuable addition to network analysis software by supporting many unique features and visualization options, especially for analysing multi-omics data sets in cancer and other diseases. .

  14. BrainNet Viewer: a network visualization tool for human brain connectomics.

    PubMed

    Xia, Mingrui; Wang, Jinhui; He, Yong

    2013-01-01

    The human brain is a complex system whose topological organization can be represented using connectomics. Recent studies have shown that human connectomes can be constructed using various neuroimaging technologies and further characterized using sophisticated analytic strategies, such as graph theory. These methods reveal the intriguing topological architectures of human brain networks in healthy populations and explore the changes throughout normal development and aging and under various pathological conditions. However, given the huge complexity of this methodology, toolboxes for graph-based network visualization are still lacking. Here, using MATLAB with a graphical user interface (GUI), we developed a graph-theoretical network visualization toolbox, called BrainNet Viewer, to illustrate human connectomes as ball-and-stick models. Within this toolbox, several combinations of defined files with connectome information can be loaded to display different combinations of brain surface, nodes and edges. In addition, display properties, such as the color and size of network elements or the layout of the figure, can be adjusted within a comprehensive but easy-to-use settings panel. Moreover, BrainNet Viewer draws the brain surface, nodes and edges in sequence and displays brain networks in multiple views, as required by the user. The figure can be manipulated with certain interaction functions to display more detailed information. Furthermore, the figures can be exported as commonly used image file formats or demonstration video for further use. BrainNet Viewer helps researchers to visualize brain networks in an easy, flexible and quick manner, and this software is freely available on the NITRC website (www.nitrc.org/projects/bnv/).

  15. Hebbian learning of hand-centred representations in a hierarchical neural network model of the primate visual system.

    PubMed

    Born, Jannis; Galeazzi, Juan M; Stringer, Simon M

    2017-01-01

    A subset of neurons in the posterior parietal and premotor areas of the primate brain respond to the locations of visual targets in a hand-centred frame of reference. Such hand-centred visual representations are thought to play an important role in visually-guided reaching to target locations in space. In this paper we show how a biologically plausible, Hebbian learning mechanism may account for the development of localized hand-centred representations in a hierarchical neural network model of the primate visual system, VisNet. The hand-centered neurons developed in the model use an invariance learning mechanism known as continuous transformation (CT) learning. In contrast to previous theoretical proposals for the development of hand-centered visual representations, CT learning does not need a memory trace of recent neuronal activity to be incorporated in the synaptic learning rule. Instead, CT learning relies solely on a Hebbian learning rule, which is able to exploit the spatial overlap that naturally occurs between successive images of a hand-object configuration as it is shifted across different retinal locations due to saccades. Our simulations show how individual neurons in the network model can learn to respond selectively to target objects in particular locations with respect to the hand, irrespective of where the hand-object configuration occurs on the retina. The response properties of these hand-centred neurons further generalise to localised receptive fields in the hand-centred space when tested on novel hand-object configurations that have not been explored during training. Indeed, even when the network is trained with target objects presented across a near continuum of locations around the hand during training, the model continues to develop hand-centred neurons with localised receptive fields in hand-centred space. With the help of principal component analysis, we provide the first theoretical framework that explains the behavior of Hebbian learning in VisNet.

  16. Hebbian learning of hand-centred representations in a hierarchical neural network model of the primate visual system

    PubMed Central

    Born, Jannis; Stringer, Simon M.

    2017-01-01

    A subset of neurons in the posterior parietal and premotor areas of the primate brain respond to the locations of visual targets in a hand-centred frame of reference. Such hand-centred visual representations are thought to play an important role in visually-guided reaching to target locations in space. In this paper we show how a biologically plausible, Hebbian learning mechanism may account for the development of localized hand-centred representations in a hierarchical neural network model of the primate visual system, VisNet. The hand-centered neurons developed in the model use an invariance learning mechanism known as continuous transformation (CT) learning. In contrast to previous theoretical proposals for the development of hand-centered visual representations, CT learning does not need a memory trace of recent neuronal activity to be incorporated in the synaptic learning rule. Instead, CT learning relies solely on a Hebbian learning rule, which is able to exploit the spatial overlap that naturally occurs between successive images of a hand-object configuration as it is shifted across different retinal locations due to saccades. Our simulations show how individual neurons in the network model can learn to respond selectively to target objects in particular locations with respect to the hand, irrespective of where the hand-object configuration occurs on the retina. The response properties of these hand-centred neurons further generalise to localised receptive fields in the hand-centred space when tested on novel hand-object configurations that have not been explored during training. Indeed, even when the network is trained with target objects presented across a near continuum of locations around the hand during training, the model continues to develop hand-centred neurons with localised receptive fields in hand-centred space. With the help of principal component analysis, we provide the first theoretical framework that explains the behavior of Hebbian learning in VisNet. PMID:28562618

  17. Reduction of Complexity: An Aspect of Network Visualization

    DTIC Science & Technology

    2006-12-01

    research is to identify strategies for the visualization of network information. Distinction can be made between visual communication and visual...exploration (MacEachern 1994). Visual communication deals with how to visualize results of different kinds of analysis, i.e., visualization in the case

  18. sbv IMPROVER: Modern Approach to Systems Biology.

    PubMed

    Guryanova, Svetlana; Guryanova, Anna

    2017-01-01

    The increasing amount and variety of data in biosciences call for innovative methods of visualization, scientific verification, and pathway analysis. Novel approaches to biological networks and research quality control are important because of their role in development of new products, improvement, and acceleration of existing health policies and research for novel ways of solving scientific challenges. One such approach is sbv IMPROVER. It is a platform that uses crowdsourcing and verification to create biological networks with easy public access. It contains 120 networks built in Biological Expression Language (BEL) to interpret data from PubMed articles with high-quality verification available for free on the CBN database. Computable, human-readable biological networks with a structured syntax are a powerful way of representing biological information generated from high-density data. This article presents sbv IMPROVER, a crowd-verification approach for the visualization and expansion of biological networks.

  19. Coding the presence of visual objects in a recurrent neural network of visual cortex.

    PubMed

    Zwickel, Timm; Wachtler, Thomas; Eckhorn, Reinhard

    2007-01-01

    Before we can recognize a visual object, our visual system has to segregate it from its background. This requires a fast mechanism for establishing the presence and location of objects independently of their identity. Recently, border-ownership neurons were recorded in monkey visual cortex which might be involved in this task [Zhou, H., Friedmann, H., von der Heydt, R., 2000. Coding of border ownership in monkey visual cortex. J. Neurosci. 20 (17), 6594-6611]. In order to explain the basic mechanisms required for fast coding of object presence, we have developed a neural network model of visual cortex consisting of three stages. Feed-forward and lateral connections support coding of Gestalt properties, including similarity, good continuation, and convexity. Neurons of the highest area respond to the presence of an object and encode its position, invariant of its form. Feedback connections to the lowest area facilitate orientation detectors activated by contours belonging to potential objects, and thus generate the experimentally observed border-ownership property. This feedback control acts fast and significantly improves the figure-ground segregation required for the consecutive task of object recognition.

  20. Neural network models for spatial data mining, map production, and cortical direction selectivity

    NASA Astrophysics Data System (ADS)

    Parsons, Olga

    A family of ARTMAP neural networks for incremental supervised learning has been developed over the last decade. The Sensor Exploitation Group of MIT Lincoln Laboratory (LL) has incorporated an early version of this network as the recognition engine of a hierarchical system for fusion and data mining of multiple registered geospatial images. The LL system has been successfully fielded, but it is limited to target vs. non-target identifications and does not produce whole maps. This dissertation expands the capabilities of the LL system so that it learns to identify arbitrarily many target classes at once and can thus produce a whole map. This new spatial data mining system is designed particularly to cope with the highly skewed class distributions of typical mapping problems. Specification of a consistent procedure and a benchmark testbed has permitted the evaluation of candidate recognition networks as well as pre- and post-processing and feature extraction options. The resulting default ARTMAP network and mapping methodology set a standard for a variety of related mapping problems and application domains. The second part of the dissertation investigates the development of cortical direction selectivity. The possible role of visual experience and oculomotor behavior in the maturation of cells in the primary visual cortex is studied. The responses of neurons in the thalamus and cortex of the cat are modeled when natural scenes are scanned by several types of eye movements. Inspired by the Hebbian-like synaptic plasticity, which is based upon correlations between cell activations, the second-order statistical structure of thalamo-cortical activity is examined. In the simulations, patterns of neural activity that lead to a correct refinement of cell responses are observed during visual fixation, when small ocular movements occur, but are not observed in the presence of large saccades. Simulations also replicate experiments in which kittens are reared under stroboscopic illumination. The abnormal fixational eye movements of these cats may account for the puzzling finding of a specific loss of cortical direction selectivity but preservation of orientation selectivity. This work indicates that the oculomotor behavior of visual fixation may play an important role in the refinement of cell response selectivity.

  1. Three-dimensional evidence network plot system: covariate imbalances and effects in network meta-analysis explored using a new software tool.

    PubMed

    Batson, Sarah; Score, Robert; Sutton, Alex J

    2017-06-01

    The aim of the study was to develop the three-dimensional (3D) evidence network plot system-a novel web-based interactive 3D tool to facilitate the visualization and exploration of covariate distributions and imbalances across evidence networks for network meta-analysis (NMA). We developed the 3D evidence network plot system within an AngularJS environment using a third party JavaScript library (Three.js) to create the 3D element of the application. Data used to enable the creation of the 3D element for a particular topic are inputted via a Microsoft Excel template spreadsheet that has been specifically formatted to hold these data. We display and discuss the findings of applying the tool to two NMA examples considering multiple covariates. These two examples have been previously identified as having potentially important covariate effects and allow us to document the various features of the tool while illustrating how it can be used. The 3D evidence network plot system provides an immediate, intuitive, and accessible way to assess the similarity and differences between the values of covariates for individual studies within and between each treatment contrast in an evidence network. In this way, differences between the studies, which may invalidate the usual assumptions of an NMA, can be identified for further scrutiny. Hence, the tool facilitates NMA feasibility/validity assessments and aids in the interpretation of NMA results. The 3D evidence network plot system is the first tool designed specifically to visualize covariate distributions and imbalances across evidence networks in 3D. This will be of primary interest to systematic review and meta-analysis researchers and, more generally, those assessing the validity and robustness of an NMA to inform reimbursement decisions. Copyright © 2017 Elsevier Inc. All rights reserved.

  2. Visualization and Hierarchical Analysis of Flow in Discrete Fracture Network Models

    NASA Astrophysics Data System (ADS)

    Aldrich, G. A.; Gable, C. W.; Painter, S. L.; Makedonska, N.; Hamann, B.; Woodring, J.

    2013-12-01

    Flow and transport in low permeability fractured rock is primary in interconnected fracture networks. Prediction and characterization of flow and transport in fractured rock has important implications in underground repositories for hazardous materials (eg. nuclear and chemical waste), contaminant migration and remediation, groundwater resource management, and hydrocarbon extraction. We have developed methods to explicitly model flow in discrete fracture networks and track flow paths using passive particle tracking algorithms. Visualization and analysis of particle trajectory through the fracture network is important to understanding fracture connectivity, flow patterns, potential contaminant pathways and fast paths through the network. However, occlusion due to the large number of highly tessellated and intersecting fracture polygons preclude the effective use of traditional visualization methods. We would also like quantitative analysis methods to characterize the trajectory of a large number of particle paths. We have solved these problems by defining a hierarchal flow network representing the topology of particle flow through the fracture network. This approach allows us to analyses the flow and the dynamics of the system as a whole. We are able to easily query the flow network, and use paint-and-link style framework to filter the fracture geometry and particle traces based on the flow analytics. This allows us to greatly reduce occlusion while emphasizing salient features such as the principal transport pathways. Examples are shown that demonstrate the methodology and highlight how use of this new method allows quantitative analysis and characterization of flow and transport in a number of representative fracture networks.

  3. Attention reorganizes connectivity across networks in a frequency specific manner.

    PubMed

    Kwon, Soyoung; Watanabe, Masataka; Fischer, Elvira; Bartels, Andreas

    2017-01-01

    Attention allows our brain to focus its limited resources on a given task. It does so by selective modulation of neural activity and of functional connectivity (FC) across brain-wide networks. While there is extensive literature on activity changes, surprisingly few studies examined brain-wide FC modulations that can be cleanly attributed to attention compared to matched visual processing. In contrast to prior approaches, we used an ultra-long trial design that avoided transients from trial onsets, included slow fluctuations (<0.1Hz) that carry important information on FC, and allowed for frequency-segregated analyses. We found that FC derived from long blocks had a nearly two-fold higher gain compared to FC derived from traditional (short) block designs. Second, attention enhanced intrinsic (negative or positive) correlations across networks, such as between the default-mode network (DMN), the dorsal attention network (DAN), and the visual system (VIS). In contrast attention de-correlated the intrinsically correlated visual regions. Third, the de-correlation within VIS was driven primarily by high frequencies, whereas the increase in DAN-VIS predominantly by low frequencies. These results pinpoint two fundamentally distinct effects of attention on connectivity. Information flow increases between distinct large-scale networks, and de-correlation within sensory cortex indicates decreased redundancy. Copyright © 2016 Elsevier Inc. All rights reserved.

  4. CoryneRegNet 4.0 – A reference database for corynebacterial gene regulatory networks

    PubMed Central

    Baumbach, Jan

    2007-01-01

    Background Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of microorganisms deduced from literature-derived knowledge, computer predictions and global DNA microarray hybridization experiments, has opened the way for the genome-wide analysis of transcriptional regulatory networks. The large-scale reconstruction of these networks allows the in silico analysis of cell behavior in response to changing environmental conditions. We previously published CoryneRegNet, an ontology-based data warehouse of corynebacterial transcription factors and regulatory networks. Initially, it was designed to provide methods for the analysis and visualization of the gene regulatory network of Corynebacterium glutamicum. Results Now we introduce CoryneRegNet release 4.0, which integrates data on the gene regulatory networks of 4 corynebacteria, 2 mycobacteria and the model organism Escherichia coli K12. As the previous versions, CoryneRegNet provides a web-based user interface to access the database content, to allow various queries, and to support the reconstruction, analysis and visualization of regulatory networks at different hierarchical levels. In this article, we present the further improved database content of CoryneRegNet along with novel analysis features. The network visualization feature GraphVis now allows the inter-species comparisons of reconstructed gene regulatory networks and the projection of gene expression levels onto that networks. Therefore, we added stimulon data directly into the database, but also provide Web Service access to the DNA microarray analysis platform EMMA. Additionally, CoryneRegNet now provides a SOAP based Web Service server, which can easily be consumed by other bioinformatics software systems. Stimulons (imported from the database, or uploaded by the user) can be analyzed in the context of known transcriptional regulatory networks to predict putative contradictions or further gene regulatory interactions. Furthermore, it integrates protein clusters by means of heuristically solving the weighted graph cluster editing problem. In addition, it provides Web Service based access to up to date gene annotation data from GenDB. Conclusion The release 4.0 of CoryneRegNet is a comprehensive system for the integrated analysis of procaryotic gene regulatory networks. It is a versatile systems biology platform to support the efficient and large-scale analysis of transcriptional regulation of gene expression in microorganisms. It is publicly available at . PMID:17986320

  5. A network-base analysis of CMIP5 "historical" experiments

    NASA Astrophysics Data System (ADS)

    Bracco, A.; Foudalis, I.; Dovrolis, C.

    2012-12-01

    In computer science, "complex network analysis" refers to a set of metrics, modeling tools and algorithms commonly used in the study of complex nonlinear dynamical systems. Its main premise is that the underlying topology or network structure of a system has a strong impact on its dynamics and evolution. By allowing to investigate local and non-local statistical interaction, network analysis provides a powerful, but only marginally explored, framework to validate climate models and investigate teleconnections, assessing their strength, range, and impacts on the climate system. In this work we propose a new, fast, robust and scalable methodology to examine, quantify, and visualize climate sensitivity, while constraining general circulation models (GCMs) outputs with observations. The goal of our novel approach is to uncover relations in the climate system that are not (or not fully) captured by more traditional methodologies used in climate science and often adopted from nonlinear dynamical systems analysis, and to explain known climate phenomena in terms of the network structure or its metrics. Our methodology is based on a solid theoretical framework and employs mathematical and statistical tools, exploited only tentatively in climate research so far. Suitably adapted to the climate problem, these tools can assist in visualizing the trade-offs in representing global links and teleconnections among different data sets. Here we present the methodology, and compare network properties for different reanalysis data sets and a suite of CMIP5 coupled GCM outputs. With an extensive model intercomparison in terms of the climate network that each model leads to, we quantify how each model reproduces major teleconnections, rank model performances, and identify common or specific errors in comparing model outputs and observations.

  6. The Temporal Resolution of Flight Attitude Control in Dragonflies and Locusts: Lessons for the Design of Flapping-Wing MAVs

    DTIC Science & Technology

    2007-12-04

    central nevous system , consisting of a self- excited neuronal network. Even in the absence of any sensory inputs this network will 4 produce, in two...is not necessary in smaller systems . Introduction Conventional aircraft can be designed such that steady-state aerodynamics apply. Thus, it is...active damping by visual inputs, whereas the same is not necessary in smaller systems . 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17

  7. EASY-SIM: A Visual Simulation System Software Architecture with an ADA 9X Application Framework

    DTIC Science & Technology

    1994-12-01

    devop -_ ment of software systems within a domain. Because an architecture promotes reuse at the design level, systems developers do not have to devote...physically separated actors into a battlefield situation, The interaction be- tween the various simulators is accomplished by means of network connec...realized that it would be more productive to make reusable components from scratch (Sny93,31-32]. Of notable exception were the network communications

  8. A Spiking Neural Network Based Cortex-Like Mechanism and Application to Facial Expression Recognition

    PubMed Central

    Fu, Si-Yao; Yang, Guo-Sheng; Kuai, Xin-Kai

    2012-01-01

    In this paper, we present a quantitative, highly structured cortex-simulated model, which can be simply described as feedforward, hierarchical simulation of ventral stream of visual cortex using biologically plausible, computationally convenient spiking neural network system. The motivation comes directly from recent pioneering works on detailed functional decomposition analysis of the feedforward pathway of the ventral stream of visual cortex and developments on artificial spiking neural networks (SNNs). By combining the logical structure of the cortical hierarchy and computing power of the spiking neuron model, a practical framework has been presented. As a proof of principle, we demonstrate our system on several facial expression recognition tasks. The proposed cortical-like feedforward hierarchy framework has the merit of capability of dealing with complicated pattern recognition problems, suggesting that, by combining the cognitive models with modern neurocomputational approaches, the neurosystematic approach to the study of cortex-like mechanism has the potential to extend our knowledge of brain mechanisms underlying the cognitive analysis and to advance theoretical models of how we recognize face or, more specifically, perceive other people's facial expression in a rich, dynamic, and complex environment, providing a new starting point for improved models of visual cortex-like mechanism. PMID:23193391

  9. A spiking neural network based cortex-like mechanism and application to facial expression recognition.

    PubMed

    Fu, Si-Yao; Yang, Guo-Sheng; Kuai, Xin-Kai

    2012-01-01

    In this paper, we present a quantitative, highly structured cortex-simulated model, which can be simply described as feedforward, hierarchical simulation of ventral stream of visual cortex using biologically plausible, computationally convenient spiking neural network system. The motivation comes directly from recent pioneering works on detailed functional decomposition analysis of the feedforward pathway of the ventral stream of visual cortex and developments on artificial spiking neural networks (SNNs). By combining the logical structure of the cortical hierarchy and computing power of the spiking neuron model, a practical framework has been presented. As a proof of principle, we demonstrate our system on several facial expression recognition tasks. The proposed cortical-like feedforward hierarchy framework has the merit of capability of dealing with complicated pattern recognition problems, suggesting that, by combining the cognitive models with modern neurocomputational approaches, the neurosystematic approach to the study of cortex-like mechanism has the potential to extend our knowledge of brain mechanisms underlying the cognitive analysis and to advance theoretical models of how we recognize face or, more specifically, perceive other people's facial expression in a rich, dynamic, and complex environment, providing a new starting point for improved models of visual cortex-like mechanism.

  10. Re-emergence of modular brain networks in stroke recovery.

    PubMed

    Siegel, Joshua S; Seitzman, Benjamin A; Ramsey, Lenny E; Ortega, Mario; Gordon, Evan M; Dosenbach, Nico U F; Petersen, Steven E; Shulman, Gordon L; Corbetta, Maurizio

    2018-04-01

    Studies of stroke have identified local reorganization in perilesional tissue. However, because the brain is highly networked, strokes also broadly alter the brain's global network organization. Here, we assess brain network structure longitudinally in adult stroke patients using resting state fMRI. The topology and boundaries of cortical regions remain grossly unchanged across recovery. In contrast, the modularity of brain systems i.e. the degree of integration within and segregation between networks, was significantly reduced sub-acutely (n = 107), but partially recovered by 3 months (n = 85), and 1 year (n = 67). Importantly, network recovery correlated with recovery from language, spatial memory, and attention deficits, but not motor or visual deficits. Finally, in-depth single subject analyses were conducted using tools for visualization of changes in brain networks over time. This exploration indicated that changes in modularity during successful recovery reflect specific alterations in the relationships between different networks. For example, in a patient with left temporo-parietal stroke and severe aphasia, sub-acute loss of modularity reflected loss of association between frontal and temporo-parietal regions bi-hemispherically across multiple modules. These long-distance connections then returned over time, paralleling aphasia recovery. This work establishes the potential importance of normalization of large-scale modular brain systems in stroke recovery. Copyright © 2017. Published by Elsevier Ltd.

  11. MET network in PubMed: a text-mined network visualization and curation system.

    PubMed

    Dai, Hong-Jie; Su, Chu-Hsien; Lai, Po-Ting; Huang, Ming-Siang; Jonnagaddala, Jitendra; Rose Jue, Toni; Rao, Shruti; Chou, Hui-Jou; Milacic, Marija; Singh, Onkar; Syed-Abdul, Shabbir; Hsu, Wen-Lian

    2016-01-01

    Metastasis is the dissemination of a cancer/tumor from one organ to another, and it is the most dangerous stage during cancer progression, causing more than 90% of cancer deaths. Improving the understanding of the complicated cellular mechanisms underlying metastasis requires investigations of the signaling pathways. To this end, we developed a METastasis (MET) network visualization and curation tool to assist metastasis researchers retrieve network information of interest while browsing through the large volume of studies in PubMed. MET can recognize relations among genes, cancers, tissues and organs of metastasis mentioned in the literature through text-mining techniques, and then produce a visualization of all mined relations in a metastasis network. To facilitate the curation process, MET is developed as a browser extension that allows curators to review and edit concepts and relations related to metastasis directly in PubMed. PubMed users can also view the metastatic networks integrated from the large collection of research papers directly through MET. For the BioCreative 2015 interactive track (IAT), a curation task was proposed to curate metastatic networks among PubMed abstracts. Six curators participated in the proposed task and a post-IAT task, curating 963 unique metastatic relations from 174 PubMed abstracts using MET.Database URL: http://btm.tmu.edu.tw/metastasisway. © The Author(s) 2016. Published by Oxford University Press.

  12. Network of anatomical texts (NAnaTex), an open-source project for visualizing the interaction between anatomical terms.

    PubMed

    Momota, Ryusuke; Ohtsuka, Aiji

    2018-01-01

    Anatomy is the science and art of understanding the structure of the body and its components in relation to the functions of the whole-body system. Medicine is based on a deep understanding of anatomy, but quite a few introductory-level learners are overwhelmed by the sheer amount of anatomical terminology that must be understood, so they regard anatomy as a dull and dense subject. To help them learn anatomical terms in a more contextual way, we started a new open-source project, the Network of Anatomical Texts (NAnaTex), which visualizes relationships of body components by integrating text-based anatomical information using Cytoscape, a network visualization software platform. Here, we present a network of bones and muscles produced from literature descriptions. As this network is primarily text-based and does not require any programming knowledge, it is easy to implement new functions or provide extra information by making changes to the original text files. To facilitate collaborations, we deposited the source code files for the network into the GitHub repository ( https://github.com/ryusukemomota/nanatex ) so that anybody can participate in the evolution of the network and use it for their own non-profit purposes. This project should help not only introductory-level learners but also professional medical practitioners, who could use it as a quick reference.

  13. Integrating conflict detection and attentional control mechanisms.

    PubMed

    Walsh, Bong J; Buonocore, Michael H; Carter, Cameron S; Mangun, George R

    2011-09-01

    Human behavior involves monitoring and adjusting performance to meet established goals. Performance-monitoring systems that act by detecting conflict in stimulus and response processing have been hypothesized to influence cortical control systems to adjust and improve performance. Here we used fMRI to investigate the neural mechanisms of conflict monitoring and resolution during voluntary spatial attention. We tested the hypothesis that the ACC would be sensitive to conflict during attentional orienting and influence activity in the frontoparietal attentional control network that selectively modulates visual information processing. We found that activity in ACC increased monotonically with increasing attentional conflict. This increased conflict detection activity was correlated with both increased activity in the attentional control network and improved speed and accuracy from one trial to the next. These results establish a long hypothesized interaction between conflict detection systems and neural systems supporting voluntary control of visual attention.

  14. Advanced visualization platform for surgical operating room coordination: distributed video board system.

    PubMed

    Hu, Peter F; Xiao, Yan; Ho, Danny; Mackenzie, Colin F; Hu, Hao; Voigt, Roger; Martz, Douglas

    2006-06-01

    One of the major challenges for day-of-surgery operating room coordination is accurate and timely situation awareness. Distributed and secure real-time status information is key to addressing these challenges. This article reports on the design and implementation of a passive status monitoring system in a 19-room surgical suite of a major academic medical center. Key design requirements considered included integrated real-time operating room status display, access control, security, and network impact. The system used live operating room video images and patient vital signs obtained through monitors to automatically update events and operating room status. Images were presented on a "need-to-know" basis, and access was controlled by identification badge authorization. The system delivered reliable real-time operating room images and status with acceptable network impact. Operating room status was visualized at 4 separate locations and was used continuously by clinicians and operating room service providers to coordinate operating room activities.

  15. RedeR: R/Bioconductor package for representing modular structures, nested networks and multiple levels of hierarchical associations

    PubMed Central

    2012-01-01

    Visualization and analysis of molecular networks are both central to systems biology. However, there still exists a large technological gap between them, especially when assessing multiple network levels or hierarchies. Here we present RedeR, an R/Bioconductor package combined with a Java core engine for representing modular networks. The functionality of RedeR is demonstrated in two different scenarios: hierarchical and modular organization in gene co-expression networks and nested structures in time-course gene expression subnetworks. Our results demonstrate RedeR as a new framework to deal with the multiple network levels that are inherent to complex biological systems. RedeR is available from http://bioconductor.org/packages/release/bioc/html/RedeR.html. PMID:22531049

  16. Towards a Comprehensive Computational Simulation System for Turbomachinery

    NASA Technical Reports Server (NTRS)

    Shih, Ming-Hsin

    1994-01-01

    The objective of this work is to develop algorithms associated with a comprehensive computational simulation system for turbomachinery flow fields. This development is accomplished in a modular fashion. These modules includes grid generation, visualization, network, simulation, toolbox, and flow modules. An interactive grid generation module is customized to facilitate the grid generation process associated with complicated turbomachinery configurations. With its user-friendly graphical user interface, the user may interactively manipulate the default settings to obtain a quality grid within a fraction of time that is usually required for building a grid about the same geometry with a general-purpose grid generation code. Non-Uniform Rational B-Spline formulations are utilized in the algorithm to maintain geometry fidelity while redistributing grid points on the solid surfaces. Bezier curve formulation is used to allow interactive construction of inner boundaries. It is also utilized to allow interactive point distribution. Cascade surfaces are transformed from three-dimensional surfaces of revolution into two-dimensional parametric planes for easy manipulation. Such a transformation allows these manipulated plane grids to be mapped to surfaces of revolution by any generatrix definition. A sophisticated visualization module is developed to al-low visualization for both grid and flow solution, steady or unsteady. A network module is built to allow data transferring in the heterogeneous environment. A flow module is integrated into this system, using an existing turbomachinery flow code. A simulation module is developed to combine the network, flow, and visualization module to achieve near real-time flow simulation about turbomachinery geometries. A toolbox module is developed to support the overall task. A batch version of the grid generation module is developed to allow portability and has been extended to allow dynamic grid generation for pitch changing turbomachinery configurations. Various applications with different characteristics are presented to demonstrate the success of this system.

  17. Visualizing Dynamic Bitcoin Transaction Patterns.

    PubMed

    McGinn, Dan; Birch, David; Akroyd, David; Molina-Solana, Miguel; Guo, Yike; Knottenbelt, William J

    2016-06-01

    This work presents a systemic top-down visualization of Bitcoin transaction activity to explore dynamically generated patterns of algorithmic behavior. Bitcoin dominates the cryptocurrency markets and presents researchers with a rich source of real-time transactional data. The pseudonymous yet public nature of the data presents opportunities for the discovery of human and algorithmic behavioral patterns of interest to many parties such as financial regulators, protocol designers, and security analysts. However, retaining visual fidelity to the underlying data to retain a fuller understanding of activity within the network remains challenging, particularly in real time. We expose an effective force-directed graph visualization employed in our large-scale data observation facility to accelerate this data exploration and derive useful insight among domain experts and the general public alike. The high-fidelity visualizations demonstrated in this article allowed for collaborative discovery of unexpected high frequency transaction patterns, including automated laundering operations, and the evolution of multiple distinct algorithmic denial of service attacks on the Bitcoin network.

  18. Visualizing Dynamic Bitcoin Transaction Patterns

    PubMed Central

    McGinn, Dan; Birch, David; Akroyd, David; Molina-Solana, Miguel; Guo, Yike; Knottenbelt, William J.

    2016-01-01

    Abstract This work presents a systemic top-down visualization of Bitcoin transaction activity to explore dynamically generated patterns of algorithmic behavior. Bitcoin dominates the cryptocurrency markets and presents researchers with a rich source of real-time transactional data. The pseudonymous yet public nature of the data presents opportunities for the discovery of human and algorithmic behavioral patterns of interest to many parties such as financial regulators, protocol designers, and security analysts. However, retaining visual fidelity to the underlying data to retain a fuller understanding of activity within the network remains challenging, particularly in real time. We expose an effective force-directed graph visualization employed in our large-scale data observation facility to accelerate this data exploration and derive useful insight among domain experts and the general public alike. The high-fidelity visualizations demonstrated in this article allowed for collaborative discovery of unexpected high frequency transaction patterns, including automated laundering operations, and the evolution of multiple distinct algorithmic denial of service attacks on the Bitcoin network. PMID:27441715

  19. Integrating Time-Synchronized Video with Other Geospatial and Temporal Data for Remote Science Operations

    NASA Technical Reports Server (NTRS)

    Cohen, Tamar E.; Lees, David S.; Deans, Matthew C.; Lim, Darlene S. S.; Lee, Yeon Jin Grace

    2018-01-01

    Exploration Ground Data Systems (xGDS) supports rapid scientific decision making by synchronizing video in context with map, instrument data visualization, geo-located notes and any other collected data. xGDS is an open source web-based software suite developed at NASA Ames Research Center to support remote science operations in analog missions and prototype solutions for remote planetary exploration. (See Appendix B) Typical video systems are designed to play or stream video only, independent of other data collected in the context of the video. Providing customizable displays for monitoring live video and data as well as replaying recorded video and data helps end users build up a rich situational awareness. xGDS was designed to support remote field exploration with unreliable networks. Commercial digital recording systems operate under the assumption that there is a stable and reliable network between the source of the video and the recording system. In many field deployments and space exploration scenarios, this is not the case - there are both anticipated and unexpected network losses. xGDS' Video Module handles these interruptions, storing the available video, organizing and characterizing the dropouts, and presenting the video for streaming or replay to the end user including visualization of the dropouts. Scientific instruments often require custom or expensive software to analyze and visualize collected data. This limits the speed at which the data can be visualized and limits access to the data to those users with the software. xGDS' Instrument Module integrates with instruments that collect and broadcast data in a single snapshot or that continually collect and broadcast a stream of data. While seeing a visualization of collected instrument data is informative, showing the context for the collected data, other data collected nearby along with events indicating current status helps remote science teams build a better understanding of the environment. Further, sharing geo-located, tagged notes recorded by the scientists and others on the team spurs deeper analysis of the data.

  20. Real time unsupervised learning of visual stimuli in neuromorphic VLSI systems

    NASA Astrophysics Data System (ADS)

    Giulioni, Massimiliano; Corradi, Federico; Dante, Vittorio; Del Giudice, Paolo

    2015-10-01

    Neuromorphic chips embody computational principles operating in the nervous system, into microelectronic devices. In this domain it is important to identify computational primitives that theory and experiments suggest as generic and reusable cognitive elements. One such element is provided by attractor dynamics in recurrent networks. Point attractors are equilibrium states of the dynamics (up to fluctuations), determined by the synaptic structure of the network; a ‘basin’ of attraction comprises all initial states leading to a given attractor upon relaxation, hence making attractor dynamics suitable to implement robust associative memory. The initial network state is dictated by the stimulus, and relaxation to the attractor state implements the retrieval of the corresponding memorized prototypical pattern. In a previous work we demonstrated that a neuromorphic recurrent network of spiking neurons and suitably chosen, fixed synapses supports attractor dynamics. Here we focus on learning: activating on-chip synaptic plasticity and using a theory-driven strategy for choosing network parameters, we show that autonomous learning, following repeated presentation of simple visual stimuli, shapes a synaptic connectivity supporting stimulus-selective attractors. Associative memory develops on chip as the result of the coupled stimulus-driven neural activity and ensuing synaptic dynamics, with no artificial separation between learning and retrieval phases.

  1. Real time unsupervised learning of visual stimuli in neuromorphic VLSI systems.

    PubMed

    Giulioni, Massimiliano; Corradi, Federico; Dante, Vittorio; del Giudice, Paolo

    2015-10-14

    Neuromorphic chips embody computational principles operating in the nervous system, into microelectronic devices. In this domain it is important to identify computational primitives that theory and experiments suggest as generic and reusable cognitive elements. One such element is provided by attractor dynamics in recurrent networks. Point attractors are equilibrium states of the dynamics (up to fluctuations), determined by the synaptic structure of the network; a 'basin' of attraction comprises all initial states leading to a given attractor upon relaxation, hence making attractor dynamics suitable to implement robust associative memory. The initial network state is dictated by the stimulus, and relaxation to the attractor state implements the retrieval of the corresponding memorized prototypical pattern. In a previous work we demonstrated that a neuromorphic recurrent network of spiking neurons and suitably chosen, fixed synapses supports attractor dynamics. Here we focus on learning: activating on-chip synaptic plasticity and using a theory-driven strategy for choosing network parameters, we show that autonomous learning, following repeated presentation of simple visual stimuli, shapes a synaptic connectivity supporting stimulus-selective attractors. Associative memory develops on chip as the result of the coupled stimulus-driven neural activity and ensuing synaptic dynamics, with no artificial separation between learning and retrieval phases.

  2. NAP: The Network Analysis Profiler, a web tool for easier topological analysis and comparison of medium-scale biological networks.

    PubMed

    Theodosiou, Theodosios; Efstathiou, Georgios; Papanikolaou, Nikolas; Kyrpides, Nikos C; Bagos, Pantelis G; Iliopoulos, Ioannis; Pavlopoulos, Georgios A

    2017-07-14

    Nowadays, due to the technological advances of high-throughput techniques, Systems Biology has seen a tremendous growth of data generation. With network analysis, looking at biological systems at a higher level in order to better understand a system, its topology and the relationships between its components is of a great importance. Gene expression, signal transduction, protein/chemical interactions, biomedical literature co-occurrences, are few of the examples captured in biological network representations where nodes represent certain bioentities and edges represent the connections between them. Today, many tools for network visualization and analysis are available. Nevertheless, most of them are standalone applications that often (i) burden users with computing and calculation time depending on the network's size and (ii) focus on handling, editing and exploring a network interactively. While such functionality is of great importance, limited efforts have been made towards the comparison of the topological analysis of multiple networks. Network Analysis Provider (NAP) is a comprehensive web tool to automate network profiling and intra/inter-network topology comparison. It is designed to bridge the gap between network analysis, statistics, graph theory and partially visualization in a user-friendly way. It is freely available and aims to become a very appealing tool for the broader community. It hosts a great plethora of topological analysis methods such as node and edge rankings. Few of its powerful characteristics are: its ability to enable easy profile comparisons across multiple networks, find their intersection and provide users with simplified, high quality plots of any of the offered topological characteristics against any other within the same network. It is written in R and Shiny, it is based on the igraph library and it is able to handle medium-scale weighted/unweighted, directed/undirected and bipartite graphs. NAP is available at http://bioinformatics.med.uoc.gr/NAP .

  3. The stimulus-evoked population response in visual cortex of awake monkey is a propagating wave

    PubMed Central

    Muller, Lyle; Reynaud, Alexandre; Chavane, Frédéric; Destexhe, Alain

    2014-01-01

    Propagating waves occur in many excitable media and were recently found in neural systems from retina to neocortex. While propagating waves are clearly present under anaesthesia, whether they also appear during awake and conscious states remains unclear. One possibility is that these waves are systematically missed in trial-averaged data, due to variability. Here we present a method for detecting propagating waves in noisy multichannel recordings. Applying this method to single-trial voltage-sensitive dye imaging data, we show that the stimulus-evoked population response in primary visual cortex of the awake monkey propagates as a travelling wave, with consistent dynamics across trials. A network model suggests that this reliability is the hallmark of the horizontal fibre network of superficial cortical layers. Propagating waves with similar properties occur independently in secondary visual cortex, but maintain precise phase relations with the waves in primary visual cortex. These results show that, in response to a visual stimulus, propagating waves are systematically evoked in several visual areas, generating a consistent spatiotemporal frame for further neuronal interactions. PMID:24770473

  4. The visual development of hand-centered receptive fields in a neural network model of the primate visual system trained with experimentally recorded human gaze changes

    PubMed Central

    Galeazzi, Juan M.; Navajas, Joaquín; Mender, Bedeho M. W.; Quian Quiroga, Rodrigo; Minini, Loredana; Stringer, Simon M.

    2016-01-01

    ABSTRACT Neurons have been found in the primate brain that respond to objects in specific locations in hand-centered coordinates. A key theoretical challenge is to explain how such hand-centered neuronal responses may develop through visual experience. In this paper we show how hand-centered visual receptive fields can develop using an artificial neural network model, VisNet, of the primate visual system when driven by gaze changes recorded from human test subjects as they completed a jigsaw. A camera mounted on the head captured images of the hand and jigsaw, while eye movements were recorded using an eye-tracking device. This combination of data allowed us to reconstruct the retinal images seen as humans undertook the jigsaw task. These retinal images were then fed into the neural network model during self-organization of its synaptic connectivity using a biologically plausible trace learning rule. A trace learning mechanism encourages neurons in the model to learn to respond to input images that tend to occur in close temporal proximity. In the data recorded from human subjects, we found that the participant’s gaze often shifted through a sequence of locations around a fixed spatial configuration of the hand and one of the jigsaw pieces. In this case, trace learning should bind these retinal images together onto the same subset of output neurons. The simulation results consequently confirmed that some cells learned to respond selectively to the hand and a jigsaw piece in a fixed spatial configuration across different retinal views. PMID:27253452

  5. The visual development of hand-centered receptive fields in a neural network model of the primate visual system trained with experimentally recorded human gaze changes.

    PubMed

    Galeazzi, Juan M; Navajas, Joaquín; Mender, Bedeho M W; Quian Quiroga, Rodrigo; Minini, Loredana; Stringer, Simon M

    2016-01-01

    Neurons have been found in the primate brain that respond to objects in specific locations in hand-centered coordinates. A key theoretical challenge is to explain how such hand-centered neuronal responses may develop through visual experience. In this paper we show how hand-centered visual receptive fields can develop using an artificial neural network model, VisNet, of the primate visual system when driven by gaze changes recorded from human test subjects as they completed a jigsaw. A camera mounted on the head captured images of the hand and jigsaw, while eye movements were recorded using an eye-tracking device. This combination of data allowed us to reconstruct the retinal images seen as humans undertook the jigsaw task. These retinal images were then fed into the neural network model during self-organization of its synaptic connectivity using a biologically plausible trace learning rule. A trace learning mechanism encourages neurons in the model to learn to respond to input images that tend to occur in close temporal proximity. In the data recorded from human subjects, we found that the participant's gaze often shifted through a sequence of locations around a fixed spatial configuration of the hand and one of the jigsaw pieces. In this case, trace learning should bind these retinal images together onto the same subset of output neurons. The simulation results consequently confirmed that some cells learned to respond selectively to the hand and a jigsaw piece in a fixed spatial configuration across different retinal views.

  6. Towards systems neuroscience of ADHD: A meta-analysis of 55 fMRI studies

    PubMed Central

    Cortese, Samuele; Kelly, Clare; Chabernaud, Camille; Proal, Erika; Di Martino, Adriana; Milham, Michael P.; Castellanos, F. Xavier

    2013-01-01

    Objective To perform a comprehensive meta-analysis of task-based functional MRI studies of Attention-Deficit/Hyperactivity Disorder (ADHD). Method PubMed, Ovid, EMBASE, Web of Science, ERIC, CINHAL, and NeuroSynth were searched for studies published through 06/30/2011. Significant differences in activation of brain regions between individuals with ADHD and comparisons were detected using activation likelihood estimation meta-analysis (p<0.05, corrected). Dysfunctional regions in ADHD were related to seven reference neuronal systems. We performed a set of meta-analyses focused on age groups (children; adults), clinical characteristics (history of stimulant treatment; presence of psychiatric comorbidities), and specific neuropsychological tasks (inhibition; working memory; vigilance/attention). Results Fifty-five studies were included (39 in children, 16 in adults). In children, hypoactivation in ADHD vs. comparisons was found mostly in systems involved in executive functions (frontoparietal network) and attention (ventral attentional network). Significant hyperactivation in ADHD vs. comparisons was observed predominantly within the default, ventral attention, and somatomotor networks. In adults, ADHD-related hypoactivation was predominant in the frontoparietal system, while ADHD-related hyperactivation was present in the visual, dorsal attention, and default networks. Significant ADHD-related dysfunction largely reflected task features and was detected even in the absence of comorbid mental disorders or history of stimulant treatment. Conclusions A growing literature provides evidence of ADHD-related dysfunction within multiple neuronal systems involved in higher-level cognitive functions but also in sensorimotor processes, including the visual system, and in the default network. This meta-analytic evidence extends early models of ADHD pathophysiology focused on prefrontal-striatal circuits. PMID:22983386

  7. Motor Imagery Learning Modulates Functional Connectivity of Multiple Brain Systems in Resting State

    PubMed Central

    Zhang, Hang; Long, Zhiying; Ge, Ruiyang; Xu, Lele; Jin, Zhen; Yao, Li; Liu, Yijun

    2014-01-01

    Background Learning motor skills involves subsequent modulation of resting-state functional connectivity in the sensory-motor system. This idea was mostly derived from the investigations on motor execution learning which mainly recruits the processing of sensory-motor information. Behavioral evidences demonstrated that motor skills in our daily lives could be learned through imagery procedures. However, it remains unclear whether the modulation of resting-state functional connectivity also exists in the sensory-motor system after motor imagery learning. Methodology/Principal Findings We performed a fMRI investigation on motor imagery learning from resting state. Based on previous studies, we identified eight sensory and cognitive resting-state networks (RSNs) corresponding to the brain systems and further explored the functional connectivity of these RSNs through the assessments, connectivity and network strengths before and after the two-week consecutive learning. Two intriguing results were revealed: (1) The sensory RSNs, specifically sensory-motor and lateral visual networks exhibited greater connectivity strengths in precuneus and fusiform gyrus after learning; (2) Decreased network strength induced by learning was proved in the default mode network, a cognitive RSN. Conclusions/Significance These results indicated that resting-state functional connectivity could be modulated by motor imagery learning in multiple brain systems, and such modulation displayed in the sensory-motor, visual and default brain systems may be associated with the establishment of motor schema and the regulation of introspective thought. These findings further revealed the neural substrates underlying motor skill learning and potentially provided new insights into the therapeutic benefits of motor imagery learning. PMID:24465577

  8. Network Visualization Project (NVP)

    DTIC Science & Technology

    2016-07-01

    network visualization, network traffic analysis, network forensics 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT UU 18. NUMBER OF...shell, is a command-line framework used for network forensic analysis. Dshell processes existing pcap files and filters output information based on

  9. TreeNetViz: revealing patterns of networks over tree structures.

    PubMed

    Gou, Liang; Zhang, Xiaolong Luke

    2011-12-01

    Network data often contain important attributes from various dimensions such as social affiliations and areas of expertise in a social network. If such attributes exhibit a tree structure, visualizing a compound graph consisting of tree and network structures becomes complicated. How to visually reveal patterns of a network over a tree has not been fully studied. In this paper, we propose a compound graph model, TreeNet, to support visualization and analysis of a network at multiple levels of aggregation over a tree. We also present a visualization design, TreeNetViz, to offer the multiscale and cross-scale exploration and interaction of a TreeNet graph. TreeNetViz uses a Radial, Space-Filling (RSF) visualization to represent the tree structure, a circle layout with novel optimization to show aggregated networks derived from TreeNet, and an edge bundling technique to reduce visual complexity. Our circular layout algorithm reduces both total edge-crossings and edge length and also considers hierarchical structure constraints and edge weight in a TreeNet graph. These experiments illustrate that the algorithm can reduce visual cluttering in TreeNet graphs. Our case study also shows that TreeNetViz has the potential to support the analysis of a compound graph by revealing multiscale and cross-scale network patterns. © 2011 IEEE

  10. FNV: light-weight flash-based network and pathway viewer.

    PubMed

    Dannenfelser, Ruth; Lachmann, Alexander; Szenk, Mariola; Ma'ayan, Avi

    2011-04-15

    Network diagrams are commonly used to visualize biochemical pathways by displaying the relationships between genes, proteins, mRNAs, microRNAs, metabolites, regulatory DNA elements, diseases, viruses and drugs. While there are several currently available web-based pathway viewers, there is still room for improvement. To this end, we have developed a flash-based network viewer (FNV) for the visualization of small to moderately sized biological networks and pathways. Written in Adobe ActionScript 3.0, the viewer accepts simple Extensible Markup Language (XML) formatted input files to display pathways in vector graphics on any web-page providing flexible layout options, interactivity with the user through tool tips, hyperlinks and the ability to rearrange nodes on the screen. FNV was utilized as a component in several web-based systems, namely Genes2Networks, Lists2Networks, KEA, ChEA and PathwayGenerator. In addition, FVN can be used to embed pathways inside pdf files for the communication of pathways in soft publication materials. FNV is available for use and download along with the supporting documentation and sample networks at http://www.maayanlab.net/FNV. avi.maayan@mssm.edu.

  11. Drawing Road Networks with Mental Maps.

    PubMed

    Lin, Shih-Syun; Lin, Chao-Hung; Hu, Yan-Jhang; Lee, Tong-Yee

    2014-09-01

    Tourist and destination maps are thematic maps designed to represent specific themes in maps. The road network topologies in these maps are generally more important than the geometric accuracy of roads. A road network warping method is proposed to facilitate map generation and improve theme representation in maps. The basic idea is deforming a road network to meet a user-specified mental map while an optimization process is performed to propagate distortions originating from road network warping. To generate a map, the proposed method includes algorithms for estimating road significance and for deforming a road network according to various geometric and aesthetic constraints. The proposed method can produce an iconic mark of a theme from a road network and meet a user-specified mental map. Therefore, the resulting map can serve as a tourist or destination map that not only provides visual aids for route planning and navigation tasks, but also visually emphasizes the presentation of a theme in a map for the purpose of advertising. In the experiments, the demonstrations of map generations show that our method enables map generation systems to generate deformed tourist and destination maps efficiently.

  12. Toward systems neuroscience in mild cognitive impairment and Alzheimer's disease: a meta-analysis of 75 fMRI studies.

    PubMed

    Li, Hui-Jie; Hou, Xiao-Hui; Liu, Han-Hui; Yue, Chun-Lin; He, Yong; Zuo, Xi-Nian

    2015-03-01

    Most of the previous task functional magnetic resonance imaging (fMRI) studies found abnormalities in distributed brain regions in mild cognitive impairment (MCI) and Alzheimer's disease (AD), and few studies investigated the brain network dysfunction from the system level. In this meta-analysis, we aimed to examine brain network dysfunction in MCI and AD. We systematically searched task-based fMRI studies in MCI and AD published between January 1990 and January 2014. Activation likelihood estimation meta-analyses were conducted to compare the significant group differences in brain activation, the significant voxels were overlaid onto seven referenced neuronal cortical networks derived from the resting-state fMRI data of 1,000 healthy participants. Thirty-nine task-based fMRI studies (697 MCI patients and 628 healthy controls) were included in MCI-related meta-analysis while 36 task-based fMRI studies (421 AD patients and 512 healthy controls) were included in AD-related meta-analysis. The meta-analytic results revealed that MCI and AD showed abnormal regional brain activation as well as large-scale brain networks. MCI patients showed hypoactivation in default, frontoparietal, and visual networks relative to healthy controls, whereas AD-related hypoactivation mainly located in visual, default, and ventral attention networks relative to healthy controls. Both MCI-related and AD-related hyperactivation fell in frontoparietal, ventral attention, default, and somatomotor networks relative to healthy controls. MCI and AD presented different pathological while shared similar compensatory large-scale networks in fulfilling the cognitive tasks. These system-level findings are helpful to link the fundamental declines of cognitive tasks to brain networks in MCI and AD. © 2014 Wiley Periodicals, Inc.

  13. Distributed effects of methylphenidate on the network structure of the resting brain: a connectomic pattern classification analysis.

    PubMed

    Sripada, Chandra Sekhar; Kessler, Daniel; Welsh, Robert; Angstadt, Michael; Liberzon, Israel; Phan, K Luan; Scott, Clayton

    2013-11-01

    Methylphenidate is a psychostimulant medication that produces improvements in functions associated with multiple neurocognitive systems. To investigate the potentially distributed effects of methylphenidate on the brain's intrinsic network architecture, we coupled resting state imaging with multivariate pattern classification. In a within-subject, double-blind, placebo-controlled, randomized, counterbalanced, cross-over design, 32 healthy human volunteers received either methylphenidate or placebo prior to two fMRI resting state scans separated by approximately one week. Resting state connectomes were generated by placing regions of interest at regular intervals throughout the brain, and these connectomes were submitted for support vector machine analysis. We found that methylphenidate produces a distributed, reliably detected, multivariate neural signature. Methylphenidate effects were evident across multiple resting state networks, especially visual, somatomotor, and default networks. Methylphenidate reduced coupling within visual and somatomotor networks. In addition, default network exhibited decoupling with several task positive networks, consistent with methylphenidate modulation of the competitive relationship between these networks. These results suggest that connectivity changes within and between large-scale networks are potentially involved in the mechanisms by which methylphenidate improves attention functioning. Copyright © 2013 Elsevier Inc. All rights reserved.

  14. Multisensory integration processing during olfactory-visual stimulation-An fMRI graph theoretical network analysis.

    PubMed

    Ripp, Isabelle; Zur Nieden, Anna-Nora; Blankenagel, Sonja; Franzmeier, Nicolai; Lundström, Johan N; Freiherr, Jessica

    2018-05-07

    In this study, we aimed to understand how whole-brain neural networks compute sensory information integration based on the olfactory and visual system. Task-related functional magnetic resonance imaging (fMRI) data was obtained during unimodal and bimodal sensory stimulation. Based on the identification of multisensory integration processing (MIP) specific hub-like network nodes analyzed with network-based statistics using region-of-interest based connectivity matrices, we conclude the following brain areas to be important for processing the presented bimodal sensory information: right precuneus connected contralaterally to the supramarginal gyrus for memory-related imagery and phonology retrieval, and the left middle occipital gyrus connected ipsilaterally to the inferior frontal gyrus via the inferior fronto-occipital fasciculus including functional aspects of working memory. Applied graph theory for quantification of the resulting complex network topologies indicates a significantly increased global efficiency and clustering coefficient in networks including aspects of MIP reflecting a simultaneous better integration and segregation. Graph theoretical analysis of positive and negative network correlations allowing for inferences about excitatory and inhibitory network architectures revealed-not significant, but very consistent-that MIP-specific neural networks are dominated by inhibitory relationships between brain regions involved in stimulus processing. © 2018 Wiley Periodicals, Inc.

  15. Cross-frequency synchronization connects networks of fast and slow oscillations during visual working memory maintenance.

    PubMed

    Siebenhühner, Felix; Wang, Sheng H; Palva, J Matias; Palva, Satu

    2016-09-26

    Neuronal activity in sensory and fronto-parietal (FP) areas underlies the representation and attentional control, respectively, of sensory information maintained in visual working memory (VWM). Within these regions, beta/gamma phase-synchronization supports the integration of sensory functions, while synchronization in theta/alpha bands supports the regulation of attentional functions. A key challenge is to understand which mechanisms integrate neuronal processing across these distinct frequencies and thereby the sensory and attentional functions. We investigated whether such integration could be achieved by cross-frequency phase synchrony (CFS). Using concurrent magneto- and electroencephalography, we found that CFS was load-dependently enhanced between theta and alpha-gamma and between alpha and beta-gamma oscillations during VWM maintenance among visual, FP, and dorsal attention (DA) systems. CFS also connected the hubs of within-frequency-synchronized networks and its strength predicted individual VWM capacity. We propose that CFS integrates processing among synchronized neuronal networks from theta to gamma frequencies to link sensory and attentional functions.

  16. Experimental and Computational Studies of Cortical Neural Network Properties Through Signal Processing

    NASA Astrophysics Data System (ADS)

    Clawson, Wesley Patrick

    Previous studies, both theoretical and experimental, of network level dynamics in the cerebral cortex show evidence for a statistical phenomenon called criticality; a phenomenon originally studied in the context of phase transitions in physical systems and that is associated with favorable information processing in the context of the brain. The focus of this thesis is to expand upon past results with new experimentation and modeling to show a relationship between criticality and the ability to detect and discriminate sensory input. A line of theoretical work predicts maximal sensory discrimination as a functional benefit of criticality, which can then be characterized using mutual information between sensory input, visual stimulus, and neural response,. The primary finding of our experiments in the visual cortex in turtles and neuronal network modeling confirms this theoretical prediction. We show that sensory discrimination is maximized when visual cortex operates near criticality. In addition to presenting this primary finding in detail, this thesis will also address our preliminary results on change-point-detection in experimentally measured cortical dynamics.

  17. Cross-Domain Shoe Retrieval with a Semantic Hierarchy of Attribute Classification Network.

    PubMed

    Zhan, Huijing; Shi, Boxin; Kot, Alex C

    2017-08-04

    Cross-domain shoe image retrieval is a challenging problem, because the query photo from the street domain (daily life scenario) and the reference photo in the online domain (online shop images) have significant visual differences due to the viewpoint and scale variation, self-occlusion, and cluttered background. This paper proposes the Semantic Hierarchy Of attributE Convolutional Neural Network (SHOE-CNN) with a three-level feature representation for discriminative shoe feature expression and efficient retrieval. The SHOE-CNN with its newly designed loss function systematically merges semantic attributes of closer visual appearances to prevent shoe images with the obvious visual differences being confused with each other; the features extracted from image, region, and part levels effectively match the shoe images across different domains. We collect a large-scale shoe dataset composed of 14341 street domain and 12652 corresponding online domain images with fine-grained attributes to train our network and evaluate our system. The top-20 retrieval accuracy improves significantly over the solution with the pre-trained CNN features.

  18. Visualizing Rank Time Series of Wikipedia Top-Viewed Pages.

    PubMed

    Xia, Jing; Hou, Yumeng; Chen, Yingjie Victor; Qian, Zhenyu Cheryl; Ebert, David S; Chen, Wei

    2017-01-01

    Visual clutter is a common challenge when visualizing large rank time series data. WikiTopReader, a reader of Wikipedia page rank, lets users explore connections among top-viewed pages by connecting page-rank behaviors with page-link relations. Such a combination enhances the unweighted Wikipedia page-link network and focuses attention on the page of interest. A set of user evaluations shows that the system effectively represents evolving ranking patterns and page-wise correlation.

  19. The Display of Visual Information in Mission Command Systems: Implications for Cognitive Performance in the Command Post of the Future

    DTIC Science & Technology

    2013-08-01

    position unless so designated by other authorized documents. Citation of manufacturer’s or trade names does not constitute an official endorsement or...the presence of large volumes of time critical information. CPOF was designed to support the Army transformation to network-enabled operations. The...Cognitive Performance The visual display of information is vital to cognitive performance. For example, the poor visual design of the radar display

  20. Integrated network analysis and effective tools in plant systems biology

    PubMed Central

    Fukushima, Atsushi; Kanaya, Shigehiko; Nishida, Kozo

    2014-01-01

    One of the ultimate goals in plant systems biology is to elucidate the genotype-phenotype relationship in plant cellular systems. Integrated network analysis that combines omics data with mathematical models has received particular attention. Here we focus on the latest cutting-edge computational advances that facilitate their combination. We highlight (1) network visualization tools, (2) pathway analyses, (3) genome-scale metabolic reconstruction, and (4) the integration of high-throughput experimental data and mathematical models. Multi-omics data that contain the genome, transcriptome, proteome, and metabolome and mathematical models are expected to integrate and expand our knowledge of complex plant metabolisms. PMID:25408696

  1. Altered Connectivity of the Balance Processing Network After Tongue Stimulation in Balance-Impaired Individuals

    PubMed Central

    Tyler, Mitchell E.; Danilov, Yuri P.; Kaczmarek, Kurt A.; Meyerand, Mary E.

    2013-01-01

    Abstract Some individuals with balance impairment have hypersensitivity of the motion-sensitive visual cortices (hMT+) compared to healthy controls. Previous work showed that electrical tongue stimulation can reduce the exaggerated postural sway induced by optic flow in this subject population and decrease the hypersensitive response of hMT+. Additionally, a region within the brainstem (BS), likely containing the vestibular and trigeminal nuclei, showed increased optic flow-induced activity after tongue stimulation. The aim of this study was to understand how the modulation induced by tongue stimulation affects the balance-processing network as a whole and how modulation of BS structures can influence cortical activity. Four volumes of interest, discovered in a general linear model analysis, constitute major contributors to the balance-processing network. These regions were entered into a dynamic causal modeling analysis to map the network and measure any connection or topology changes due to the stimulation. Balance-impaired individuals had downregulated response of the primary visual cortex (V1) to visual stimuli but upregulated modulation of the connection between V1 and hMT+ by visual motion compared to healthy controls (p≤1E–5). This upregulation was decreased to near-normal levels after stimulation. Additionally, the region within the BS showed increased response to visual motion after stimulation compared to both prestimulation and controls. Stimulation to the tongue enters the central nervous system at the BS but likely propagates to the cortex through supramodal information transfer. We present a model to explain these brain responses that utilizes an anatomically present, but functionally dormant pathway of information flow within the processing network. PMID:23216162

  2. Functional evolution of new and expanded attention networks in humans

    PubMed Central

    Patel, Gaurav H.; Yang, Danica; Jamerson, Emery C.; Snyder, Lawrence H.; Corbetta, Maurizio; Ferrera, Vincent P.

    2015-01-01

    Macaques are often used as a model system for invasive investigations of the neural substrates of cognition. However, 25 million years of evolution separate humans and macaques from their last common ancestor, and this has likely substantially impacted the function of the cortical networks underlying cognitive processes, such as attention. We examined the homology of frontoparietal networks underlying attention by comparing functional MRI data from macaques and humans performing the same visual search task. Although there are broad similarities, we found fundamental differences between the species. First, humans have more dorsal attention network areas than macaques, indicating that in the course of evolution the human attention system has expanded compared with macaques. Second, potentially homologous areas in the dorsal attention network have markedly different biases toward representing the contralateral hemifield, indicating that the underlying neural architecture of these areas may differ in the most basic of properties, such as receptive field distribution. Third, despite clear evidence of the temporoparietal junction node of the ventral attention network in humans as elicited by this visual search task, we did not find functional evidence of a temporoparietal junction in macaques. None of these differences were the result of differences in training, experimental power, or anatomical variability between the two species. The results of this study indicate that macaque data should be applied to human models of cognition cautiously, and demonstrate how evolution may shape cortical networks. PMID:26170314

  3. Functional evolution of new and expanded attention networks in humans.

    PubMed

    Patel, Gaurav H; Yang, Danica; Jamerson, Emery C; Snyder, Lawrence H; Corbetta, Maurizio; Ferrera, Vincent P

    2015-07-28

    Macaques are often used as a model system for invasive investigations of the neural substrates of cognition. However, 25 million years of evolution separate humans and macaques from their last common ancestor, and this has likely substantially impacted the function of the cortical networks underlying cognitive processes, such as attention. We examined the homology of frontoparietal networks underlying attention by comparing functional MRI data from macaques and humans performing the same visual search task. Although there are broad similarities, we found fundamental differences between the species. First, humans have more dorsal attention network areas than macaques, indicating that in the course of evolution the human attention system has expanded compared with macaques. Second, potentially homologous areas in the dorsal attention network have markedly different biases toward representing the contralateral hemifield, indicating that the underlying neural architecture of these areas may differ in the most basic of properties, such as receptive field distribution. Third, despite clear evidence of the temporoparietal junction node of the ventral attention network in humans as elicited by this visual search task, we did not find functional evidence of a temporoparietal junction in macaques. None of these differences were the result of differences in training, experimental power, or anatomical variability between the two species. The results of this study indicate that macaque data should be applied to human models of cognition cautiously, and demonstrate how evolution may shape cortical networks.

  4. Network propagation in the cytoscape cyberinfrastructure.

    PubMed

    Carlin, Daniel E; Demchak, Barry; Pratt, Dexter; Sage, Eric; Ideker, Trey

    2017-10-01

    Network propagation is an important and widely used algorithm in systems biology, with applications in protein function prediction, disease gene prioritization, and patient stratification. However, up to this point it has required significant expertise to run. Here we extend the popular network analysis program Cytoscape to perform network propagation as an integrated function. Such integration greatly increases the access to network propagation by putting it in the hands of biologists and linking it to the many other types of network analysis and visualization available through Cytoscape. We demonstrate the power and utility of the algorithm by identifying mutations conferring resistance to Vemurafenib.

  5. Genotet: An Interactive Web-based Visual Exploration Framework to Support Validation of Gene Regulatory Networks.

    PubMed

    Yu, Bowen; Doraiswamy, Harish; Chen, Xi; Miraldi, Emily; Arrieta-Ortiz, Mario Luis; Hafemeister, Christoph; Madar, Aviv; Bonneau, Richard; Silva, Cláudio T

    2014-12-01

    Elucidation of transcriptional regulatory networks (TRNs) is a fundamental goal in biology, and one of the most important components of TRNs are transcription factors (TFs), proteins that specifically bind to gene promoter and enhancer regions to alter target gene expression patterns. Advances in genomic technologies as well as advances in computational biology have led to multiple large regulatory network models (directed networks) each with a large corpus of supporting data and gene-annotation. There are multiple possible biological motivations for exploring large regulatory network models, including: validating TF-target gene relationships, figuring out co-regulation patterns, and exploring the coordination of cell processes in response to changes in cell state or environment. Here we focus on queries aimed at validating regulatory network models, and on coordinating visualization of primary data and directed weighted gene regulatory networks. The large size of both the network models and the primary data can make such coordinated queries cumbersome with existing tools and, in particular, inhibits the sharing of results between collaborators. In this work, we develop and demonstrate a web-based framework for coordinating visualization and exploration of expression data (RNA-seq, microarray), network models and gene-binding data (ChIP-seq). Using specialized data structures and multiple coordinated views, we design an efficient querying model to support interactive analysis of the data. Finally, we show the effectiveness of our framework through case studies for the mouse immune system (a dataset focused on a subset of key cellular functions) and a model bacteria (a small genome with high data-completeness).

  6. Deep Neural Networks: A New Framework for Modeling Biological Vision and Brain Information Processing.

    PubMed

    Kriegeskorte, Nikolaus

    2015-11-24

    Recent advances in neural network modeling have enabled major strides in computer vision and other artificial intelligence applications. Human-level visual recognition abilities are coming within reach of artificial systems. Artificial neural networks are inspired by the brain, and their computations could be implemented in biological neurons. Convolutional feedforward networks, which now dominate computer vision, take further inspiration from the architecture of the primate visual hierarchy. However, the current models are designed with engineering goals, not to model brain computations. Nevertheless, initial studies comparing internal representations between these models and primate brains find surprisingly similar representational spaces. With human-level performance no longer out of reach, we are entering an exciting new era, in which we will be able to build biologically faithful feedforward and recurrent computational models of how biological brains perform high-level feats of intelligence, including vision.

  7. Research Trends in Wireless Visual Sensor Networks When Exploiting Prioritization

    PubMed Central

    Costa, Daniel G.; Guedes, Luiz Affonso; Vasques, Francisco; Portugal, Paulo

    2015-01-01

    The development of wireless sensor networks for control and monitoring functions has created a vibrant investigation scenario, where many critical topics, such as communication efficiency and energy consumption, have been investigated in the past few years. However, when sensors are endowed with low-power cameras for visual monitoring, a new scope of challenges is raised, demanding new research efforts. In this context, the resource-constrained nature of sensor nodes has demanded the use of prioritization approaches as a practical mechanism to lower the transmission burden of visual data over wireless sensor networks. Many works in recent years have considered local-level prioritization parameters to enhance the overall performance of those networks, but global-level policies can potentially achieve better results in terms of visual monitoring efficiency. In this paper, we make a broad review of some recent works on priority-based optimizations in wireless visual sensor networks. Moreover, we envisage some research trends when exploiting prioritization, potentially fostering the development of promising optimizations for wireless sensor networks composed of visual sensors. PMID:25599425

  8. In vivo Visuotopic Brain Mapping with Manganese-Enhanced MRI and Resting-State Functional Connectivity MRI

    PubMed Central

    Chan, Kevin C.; Fan, Shu-Juan; Chan, Russell W.; Cheng, Joe S.; Zhou, Iris Y.; Wu, Ed X.

    2014-01-01

    The rodents are an increasingly important model for understanding the mechanisms of development, plasticity, functional specialization and disease in the visual system. However, limited tools have been available for assessing the structural and functional connectivity of the visual brain network globally, in vivo and longitudinally. There are also ongoing debates on whether functional brain connectivity directly reflects structural brain connectivity. In this study, we explored the feasibility of manganese-enhanced MRI (MEMRI) via 3 different routes of Mn2+ administration for visuotopic brain mapping and understanding of physiological transport in normal and visually deprived adult rats. In addition, resting-state functional connectivity MRI (RSfcMRI) was performed to evaluate the intrinsic functional network and structural-functional relationships in the corresponding anatomical visual brain connections traced by MEMRI. Upon intravitreal, subcortical, and intracortical Mn2+ injection, different topographic and layer-specific Mn enhancement patterns could be revealed in the visual cortex and subcortical visual nuclei along retinal, callosal, cortico-subcortical, transsynaptic and intracortical horizontal connections. Loss of visual input upon monocular enucleation to adult rats appeared to reduce interhemispheric polysynaptic Mn2+ transfer but not intra- or inter-hemispheric monosynaptic Mn2+ transport after Mn2+ injection into visual cortex. In normal adults, both structural and functional connectivity by MEMRI and RSfcMRI was stronger interhemispherically between bilateral primary/secondary visual cortex (V1/V2) transition zones (TZ) than between V1/V2 TZ and other cortical nuclei. Intrahemispherically, structural and functional connectivity was stronger between visual cortex and subcortical visual nuclei than between visual cortex and other subcortical nuclei. The current results demonstrated the sensitivity of MEMRI and RSfcMRI for assessing the neuroarchitecture, neurophysiology and structural-functional relationships of the visual brains in vivo. These may possess great potentials for effective monitoring and understanding of the basic anatomical and functional connections in the visual system during development, plasticity, disease, pharmacological interventions and genetic modifications in future studies. PMID:24394694

  9. An Intelligent Cooperative Visual Sensor Network for Urban Mobility

    PubMed Central

    Leone, Giuseppe Riccardo; Petracca, Matteo; Salvetti, Ovidio; Azzarà, Andrea

    2017-01-01

    Smart cities are demanding solutions for improved traffic efficiency, in order to guarantee optimal access to mobility resources available in urban areas. Intelligent video analytics deployed directly on board embedded sensors offers great opportunities to gather highly informative data about traffic and transport, allowing reconstruction of a real-time neat picture of urban mobility patterns. In this paper, we present a visual sensor network in which each node embeds computer vision logics for analyzing in real time urban traffic. The nodes in the network share their perceptions and build a global and comprehensive interpretation of the analyzed scenes in a cooperative and adaptive fashion. This is possible thanks to an especially designed Internet of Things (IoT) compliant middleware which encompasses in-network event composition as well as full support of Machine-2-Machine (M2M) communication mechanism. The potential of the proposed cooperative visual sensor network is shown with two sample applications in urban mobility connected to the estimation of vehicular flows and parking management. Besides providing detailed results of each key component of the proposed solution, the validity of the approach is demonstrated by extensive field tests that proved the suitability of the system in providing a scalable, adaptable and extensible data collection layer for managing and understanding mobility in smart cities. PMID:29125535

  10. An Intelligent Cooperative Visual Sensor Network for Urban Mobility.

    PubMed

    Leone, Giuseppe Riccardo; Moroni, Davide; Pieri, Gabriele; Petracca, Matteo; Salvetti, Ovidio; Azzarà, Andrea; Marino, Francesco

    2017-11-10

    Smart cities are demanding solutions for improved traffic efficiency, in order to guarantee optimal access to mobility resources available in urban areas. Intelligent video analytics deployed directly on board embedded sensors offers great opportunities to gather highly informative data about traffic and transport, allowing reconstruction of a real-time neat picture of urban mobility patterns. In this paper, we present a visual sensor network in which each node embeds computer vision logics for analyzing in real time urban traffic. The nodes in the network share their perceptions and build a global and comprehensive interpretation of the analyzed scenes in a cooperative and adaptive fashion. This is possible thanks to an especially designed Internet of Things (IoT) compliant middleware which encompasses in-network event composition as well as full support of Machine-2-Machine (M2M) communication mechanism. The potential of the proposed cooperative visual sensor network is shown with two sample applications in urban mobility connected to the estimation of vehicular flows and parking management. Besides providing detailed results of each key component of the proposed solution, the validity of the approach is demonstrated by extensive field tests that proved the suitability of the system in providing a scalable, adaptable and extensible data collection layer for managing and understanding mobility in smart cities.

  11. Artificial vision by multi-layered neural networks: neocognitron and its advances.

    PubMed

    Fukushima, Kunihiko

    2013-01-01

    The neocognitron is a neural network model proposed by Fukushima (1980). Its architecture was suggested by neurophysiological findings on the visual systems of mammals. It is a hierarchical multi-layered network. It acquires the ability to robustly recognize visual patterns through learning. Although the neocognitron has a long history, modifications of the network to improve its performance are still going on. For example, a recent neocognitron uses a new learning rule, named add-if-silent, which makes the learning process much simpler and more stable. Nevertheless, a high recognition rate can be kept with a smaller scale of the network. Referring to the history of the neocognitron, this paper discusses recent advances in the neocognitron. We also show that various new functions can be realized by, for example, introducing top-down connections to the neocognitron: mechanism of selective attention, recognition and completion of partly occluded patterns, restoring occluded contours, and so on. Copyright © 2012 Elsevier Ltd. All rights reserved.

  12. A unified software framework for deriving, visualizing, and exploring abstraction networks for ontologies

    PubMed Central

    Ochs, Christopher; Geller, James; Perl, Yehoshua; Musen, Mark A.

    2016-01-01

    Software tools play a critical role in the development and maintenance of biomedical ontologies. One important task that is difficult without software tools is ontology quality assurance. In previous work, we have introduced different kinds of abstraction networks to provide a theoretical foundation for ontology quality assurance tools. Abstraction networks summarize the structure and content of ontologies. One kind of abstraction network that we have used repeatedly to support ontology quality assurance is the partial-area taxonomy. It summarizes structurally and semantically similar concepts within an ontology. However, the use of partial-area taxonomies was ad hoc and not generalizable. In this paper, we describe the Ontology Abstraction Framework (OAF), a unified framework and software system for deriving, visualizing, and exploring partial-area taxonomy abstraction networks. The OAF includes support for various ontology representations (e.g., OWL and SNOMED CT's relational format). A Protégé plugin for deriving “live partial-area taxonomies” is demonstrated. PMID:27345947

  13. A unified software framework for deriving, visualizing, and exploring abstraction networks for ontologies.

    PubMed

    Ochs, Christopher; Geller, James; Perl, Yehoshua; Musen, Mark A

    2016-08-01

    Software tools play a critical role in the development and maintenance of biomedical ontologies. One important task that is difficult without software tools is ontology quality assurance. In previous work, we have introduced different kinds of abstraction networks to provide a theoretical foundation for ontology quality assurance tools. Abstraction networks summarize the structure and content of ontologies. One kind of abstraction network that we have used repeatedly to support ontology quality assurance is the partial-area taxonomy. It summarizes structurally and semantically similar concepts within an ontology. However, the use of partial-area taxonomies was ad hoc and not generalizable. In this paper, we describe the Ontology Abstraction Framework (OAF), a unified framework and software system for deriving, visualizing, and exploring partial-area taxonomy abstraction networks. The OAF includes support for various ontology representations (e.g., OWL and SNOMED CT's relational format). A Protégé plugin for deriving "live partial-area taxonomies" is demonstrated. Copyright © 2016 Elsevier Inc. All rights reserved.

  14. The Spider Center Wide File System; From Concept to Reality

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Shipman, Galen M; Dillow, David A; Oral, H Sarp

    2009-01-01

    The Leadership Computing Facility (LCF) at Oak Ridge National Laboratory (ORNL) has a diverse portfolio of computational resources ranging from a petascale XT4/XT5 simulation system (Jaguar) to numerous other systems supporting development, visualization, and data analytics. In order to support vastly different I/O needs of these systems Spider, a Lustre-based center wide file system was designed and deployed to provide over 240 GB/s of aggregate throughput with over 10 Petabytes of formatted capacity. A multi-stage InfiniBand network, dubbed as Scalable I/O Network (SION), with over 889 GB/s of bisectional bandwidth was deployed as part of Spider to provide connectivity tomore » our simulation, development, visualization, and other platforms. To our knowledge, while writing this paper, Spider is the largest and fastest POSIX-compliant parallel file system in production. This paper will detail the overall architecture of the Spider system, challenges in deploying and initial testings of a file system of this scale, and novel solutions to these challenges which offer key insights into file system design in the future.« less

  15. Causal biological network database: a comprehensive platform of causal biological network models focused on the pulmonary and vascular systems

    PubMed Central

    Boué, Stéphanie; Talikka, Marja; Westra, Jurjen Willem; Hayes, William; Di Fabio, Anselmo; Park, Jennifer; Schlage, Walter K.; Sewer, Alain; Fields, Brett; Ansari, Sam; Martin, Florian; Veljkovic, Emilija; Kenney, Renee; Peitsch, Manuel C.; Hoeng, Julia

    2015-01-01

    With the wealth of publications and data available, powerful and transparent computational approaches are required to represent measured data and scientific knowledge in a computable and searchable format. We developed a set of biological network models, scripted in the Biological Expression Language, that reflect causal signaling pathways across a wide range of biological processes, including cell fate, cell stress, cell proliferation, inflammation, tissue repair and angiogenesis in the pulmonary and cardiovascular context. This comprehensive collection of networks is now freely available to the scientific community in a centralized web-based repository, the Causal Biological Network database, which is composed of over 120 manually curated and well annotated biological network models and can be accessed at http://causalbionet.com. The website accesses a MongoDB, which stores all versions of the networks as JSON objects and allows users to search for genes, proteins, biological processes, small molecules and keywords in the network descriptions to retrieve biological networks of interest. The content of the networks can be visualized and browsed. Nodes and edges can be filtered and all supporting evidence for the edges can be browsed and is linked to the original articles in PubMed. Moreover, networks may be downloaded for further visualization and evaluation. Database URL: http://causalbionet.com PMID:25887162

  16. Learning representation hierarchies by sharing visual features: a computational investigation of Persian character recognition with unsupervised deep learning.

    PubMed

    Sadeghi, Zahra; Testolin, Alberto

    2017-08-01

    In humans, efficient recognition of written symbols is thought to rely on a hierarchical processing system, where simple features are progressively combined into more abstract, high-level representations. Here, we present a computational model of Persian character recognition based on deep belief networks, where increasingly more complex visual features emerge in a completely unsupervised manner by fitting a hierarchical generative model to the sensory data. Crucially, high-level internal representations emerging from unsupervised deep learning can be easily read out by a linear classifier, achieving state-of-the-art recognition accuracy. Furthermore, we tested the hypothesis that handwritten digits and letters share many common visual features: A generative model that captures the statistical structure of the letters distribution should therefore also support the recognition of written digits. To this aim, deep networks trained on Persian letters were used to build high-level representations of Persian digits, which were indeed read out with high accuracy. Our simulations show that complex visual features, such as those mediating the identification of Persian symbols, can emerge from unsupervised learning in multilayered neural networks and can support knowledge transfer across related domains.

  17. The ventral visual pathway: an expanded neural framework for the processing of object quality.

    PubMed

    Kravitz, Dwight J; Saleem, Kadharbatcha S; Baker, Chris I; Ungerleider, Leslie G; Mishkin, Mortimer

    2013-01-01

    Since the original characterization of the ventral visual pathway, our knowledge of its neuroanatomy, functional properties, and extrinsic targets has grown considerably. Here we synthesize this recent evidence and propose that the ventral pathway is best understood as a recurrent occipitotemporal network containing neural representations of object quality both utilized and constrained by at least six distinct cortical and subcortical systems. Each system serves its own specialized behavioral, cognitive, or affective function, collectively providing the raison d'être for the ventral visual pathway. This expanded framework contrasts with the depiction of the ventral visual pathway as a largely serial staged hierarchy culminating in singular object representations and more parsimoniously incorporates attentional, contextual, and feedback effects. Published by Elsevier Ltd.

  18. Scientific Visualization in High Speed Network Environments

    NASA Technical Reports Server (NTRS)

    Vaziri, Arsi; Kutler, Paul (Technical Monitor)

    1997-01-01

    In several cases, new visualization techniques have vastly increased the researcher's ability to analyze and comprehend data. Similarly, the role of networks in providing an efficient supercomputing environment have become more critical and continue to grow at a faster rate than the increase in the processing capabilities of supercomputers. A close relationship between scientific visualization and high-speed networks in providing an important link to support efficient supercomputing is identified. The two technologies are driven by the increasing complexities and volume of supercomputer data. The interaction of scientific visualization and high-speed networks in a Computational Fluid Dynamics simulation/visualization environment are given. Current capabilities supported by high speed networks, supercomputers, and high-performance graphics workstations at the Numerical Aerodynamic Simulation Facility (NAS) at NASA Ames Research Center are described. Applied research in providing a supercomputer visualization environment to support future computational requirements are summarized.

  19. Software tool for data mining and its applications

    NASA Astrophysics Data System (ADS)

    Yang, Jie; Ye, Chenzhou; Chen, Nianyi

    2002-03-01

    A software tool for data mining is introduced, which integrates pattern recognition (PCA, Fisher, clustering, hyperenvelop, regression), artificial intelligence (knowledge representation, decision trees), statistical learning (rough set, support vector machine), computational intelligence (neural network, genetic algorithm, fuzzy systems). It consists of nine function models: pattern recognition, decision trees, association rule, fuzzy rule, neural network, genetic algorithm, Hyper Envelop, support vector machine, visualization. The principle and knowledge representation of some function models of data mining are described. The software tool of data mining is realized by Visual C++ under Windows 2000. Nonmonotony in data mining is dealt with by concept hierarchy and layered mining. The software tool of data mining has satisfactorily applied in the prediction of regularities of the formation of ternary intermetallic compounds in alloy systems, and diagnosis of brain glioma.

  20. An experimental investigation of the force network ensemble

    NASA Astrophysics Data System (ADS)

    Kollmer, Jonathan E.; Daniels, Karen E.

    2017-06-01

    We present an experiment in which a horizontal quasi-2D granular system with a fixed neighbor network is cyclically compressed and decompressed over 1000 cycles. We remove basal friction by floating the particles on a thin air cushion, so that particles only interact in-plane. As expected for a granular system, the applied load is not distributed uniformly, but is instead concentrated in force chains which form a network throughout the system. To visualize the structure of these networks, we use particles made from photoelastic material. The experimental setup and a new data-processing pipeline allow us to map out the evolution subject to the cyclic compressions. We characterize several statistical properties of the packing, including the probability density function of the contact force, and compare them with theoretical and numerical predictions from the force network ensemble theory.

  1. Data systems and computer science programs: Overview

    NASA Technical Reports Server (NTRS)

    Smith, Paul H.; Hunter, Paul

    1991-01-01

    An external review of the Integrated Technology Plan for the Civil Space Program is presented. The topics are presented in viewgraph form and include the following: onboard memory and storage technology; advanced flight computers; special purpose flight processors; onboard networking and testbeds; information archive, access, and retrieval; visualization; neural networks; software engineering; and flight control and operations.

  2. Blindness and Computer Networking at iTEC [Information Technology Education Center].

    ERIC Educational Resources Information Center

    Goins, Shannon

    A new program to train blind and visually impaired individuals to design and run a computer network has been developed. The program offers the Microsoft Certified Systems Engineer (MCSE) training. The program, which began in February 2001, recently graduated its first class of students, who are currently completing 1-month internships to complete…

  3. An Examination of Job Skills Posted on Internet Databases: Implications for Information Systems Degree Programs.

    ERIC Educational Resources Information Center

    Liu, Xia; Liu, Lai C.; Koong, Kai S.; Lu, June

    2003-01-01

    Analysis of 300 information technology job postings in two Internet databases identified the following skill categories: programming languages (Java, C/C++, and Visual Basic were most frequent); website development (57% sought SQL and HTML skills); databases (nearly 50% required Oracle); networks (only Windows NT or wide-area/local-area networks);…

  4. High resolution light-sheet based high-throughput imaging cytometry system enables visualization of intra-cellular organelles

    NASA Astrophysics Data System (ADS)

    Regmi, Raju; Mohan, Kavya; Mondal, Partha Pratim

    2014-09-01

    Visualization of intracellular organelles is achieved using a newly developed high throughput imaging cytometry system. This system interrogates the microfluidic channel using a sheet of light rather than the existing point-based scanning techniques. The advantages of the developed system are many, including, single-shot scanning of specimens flowing through the microfluidic channel at flow rate ranging from micro- to nano- lit./min. Moreover, this opens-up in-vivo imaging of sub-cellular structures and simultaneous cell counting in an imaging cytometry system. We recorded a maximum count of 2400 cells/min at a flow-rate of 700 nl/min, and simultaneous visualization of fluorescently-labeled mitochondrial network in HeLa cells during flow. The developed imaging cytometry system may find immediate application in biotechnology, fluorescence microscopy and nano-medicine.

  5. Default Mode Network (DMN) Deactivation during Odor-Visual Association

    PubMed Central

    Karunanayaka, Prasanna R.; Wilson, Donald A.; Tobia, Michael J.; Martinez, Brittany; Meadowcroft, Mark; Eslinger, Paul J.; Yang, Qing X.

    2017-01-01

    Default mode network (DMN) deactivation has been shown to be functionally relevant for goal-directed cognition. In this study, we investigated the DMN’s role during olfactory processing using two complementary functional magnetic resonance imaging (fMRI) paradigms with identical timing, visual-cue stimulation and response monitoring protocols. Twenty-nine healthy, non-smoking, right-handed adults (mean age = 26±4 yrs., 16 females) completed an odor-visual association fMRI paradigm that had two alternating odor+visual and visual-only trial conditions. During odor+visual trials, a visual cue was presented simultaneously with an odor, while during visual-only trial conditions the same visual cue was presented alone. Eighteen of the 29 participants (mean age = 27.0 ± 6.0 yrs.,11 females) also took part in a control no-odor fMRI paradigm that consisted of visual-only trial conditions which were identical to the visual-only trials in the odor-visual association paradigm. We used Independent Component Analysis (ICA), extended unified structural equation modeling (euSEM), and psychophysiological interaction (PPI) to investigate the interplay between the DMN and olfactory network. In the odor-visual association paradigm, DMN deactivation was evoked by both the odor+visual and visual-only trial conditions. In contrast, the visual-only trials in the no-odor paradigm did not evoke consistent DMN deactivation. In the odor-visual association paradigm, the euSEM and PPI analyses identified a directed connectivity between the DMN and olfactory network which was significantly different between odor+visual and visual-only trial conditions. The results support a strong interaction between the DMN and olfactory network and highlights DMN’s role in task-evoked brain activity and behavioral responses during olfactory processing. PMID:27785847

  6. A proto-architecture for innate directionally selective visual maps.

    PubMed

    Adams, Samantha V; Harris, Chris M

    2014-01-01

    Self-organizing artificial neural networks are a popular tool for studying visual system development, in particular the cortical feature maps present in real systems that represent properties such as ocular dominance (OD), orientation-selectivity (OR) and direction selectivity (DS). They are also potentially useful in artificial systems, for example robotics, where the ability to extract and learn features from the environment in an unsupervised way is important. In this computational study we explore a DS map that is already latent in a simple artificial network. This latent selectivity arises purely from the cortical architecture without any explicit coding for DS and prior to any self-organising process facilitated by spontaneous activity or training. We find DS maps with local patchy regions that exhibit features similar to maps derived experimentally and from previous modeling studies. We explore the consequences of changes to the afferent and lateral connectivity to establish the key features of this proto-architecture that support DS.

  7. Adaptation disrupts motion integration in the primate dorsal stream

    PubMed Central

    Patterson, Carlyn A.; Wissig, Stephanie C.; Kohn, Adam

    2014-01-01

    Summary Sensory systems adjust continuously to the environment. The effects of recent sensory experience—or adaptation—are typically assayed by recording in a relevant subcortical or cortical network. However, adaptation effects cannot be localized to a single, local network. Adjustments in one circuit or area will alter the input provided to others, with unclear consequences for computations implemented in the downstream circuit. Here we show that prolonged adaptation with drifting gratings, which alters responses in the early visual system, impedes the ability of area MT neurons to integrate motion signals in plaid stimuli. Perceptual experiments reveal a corresponding loss of plaid coherence. A simple computational model shows how the altered representation of motion signals in early cortex can derail integration in MT. Our results suggest that the effects of adaptation cascade through the visual system, derailing the downstream representation of distinct stimulus attributes. PMID:24507198

  8. New Applications for the Testing and Visualization of Wireless Networks

    NASA Technical Reports Server (NTRS)

    Griffin, Robert I.; Cauley, Michael A.; Pleva, Michael A.; Seibert, Marc A.; Lopez, Isaac

    2005-01-01

    Traditional techniques for examining wireless networks use physical link characteristics such as Signal-to-Noise (SNR) ratios to assess the performance of wireless networks. Such measurements may not be reliable indicators of available bandwidth. This work describes two new software applications developed at NASA Glenn Research Center for the investigation of wireless networks. GPSIPerf combines measurements of Transmission Control Protocol (TCP) throughput with Global Positioning System (GPS) coordinates to give users a map of wireless bandwidth for outdoor environments where a wireless infrastructure has been deployed. GPSIPerfView combines the data provided by GPSIPerf with high-resolution digital elevation maps (DEM) to help users visualize and assess the impact of elevation features on wireless networks in a given sample area. These applications were used to examine TCP throughput in several wireless network configurations at desert field sites near Hanksville, Utah during May of 2004. Use of GPSIPerf and GPSIPerfView provides a geographically referenced picture of the extent and deterioration of TCP throughput in tested wireless network configurations. GPSIPerf results from field-testing in Utah suggest that it can be useful in assessing other wireless network architectures, and may be useful to future human-robotic exploration missions.

  9. A unified data representation theory for network visualization, ordering and coarse-graining

    PubMed Central

    Kovács, István A.; Mizsei, Réka; Csermely, Péter

    2015-01-01

    Representation of large data sets became a key question of many scientific disciplines in the last decade. Several approaches for network visualization, data ordering and coarse-graining accomplished this goal. However, there was no underlying theoretical framework linking these problems. Here we show an elegant, information theoretic data representation approach as a unified solution of network visualization, data ordering and coarse-graining. The optimal representation is the hardest to distinguish from the original data matrix, measured by the relative entropy. The representation of network nodes as probability distributions provides an efficient visualization method and, in one dimension, an ordering of network nodes and edges. Coarse-grained representations of the input network enable both efficient data compression and hierarchical visualization to achieve high quality representations of larger data sets. Our unified data representation theory will help the analysis of extensive data sets, by revealing the large-scale structure of complex networks in a comprehensible form. PMID:26348923

  10. VRML metabolic network visualizer.

    PubMed

    Rojdestvenski, Igor

    2003-03-01

    A successful date collection visualization should satisfy a set of many requirements: unification of diverse data formats, support for serendipity research, support of hierarchical structures, algorithmizability, vast information density, Internet-readiness, and other. Recently, virtual reality has made significant progress in engineering, architectural design, entertainment and communication. We experiment with the possibility of using the immersive abstract three-dimensional visualizations of the metabolic networks. We present the trial Metabolic Network Visualizer software, which produces graphical representation of a metabolic network as a VRML world from a formal description written in a simple SGML-type scripting language.

  11. Functional Connectivity Estimated from Resting-State fMRI Reveals Selective Alterations in Male Adolescents with Pure Conduct Disorder

    PubMed Central

    Lu, Feng-Mei; Zhou, Jian-Song; Zhang, Jiang; Xiang, Yu-Tao; Zhang, Jian; Liu, Qi; Wang, Xiao-Ping; Yuan, Zhen

    2015-01-01

    Conduct disorder (CD) is characterized by a persistent pattern of antisocial behavior and aggression in childhood and adolescence. Previous task-based and resting-state functional magnetic resonance imaging (fMRI) studies have revealed widespread brain regional abnormalities in adolescents with CD. However, whether the resting-state networks (RSNs) are altered in adolescents with CD remains unknown. In this study, resting-state fMRI data were first acquired from eighteen male adolescents with pure CD and eighteen age- and gender-matched typically developing (TD) individuals. Independent component analysis (ICA) was implemented to extract nine representative RSNs, and the generated RSNs were then compared to show the differences between the CD and TD groups. Interestingly, it was observed from the brain mapping results that compared with the TD group, the CD group manifested decreased functional connectivity in four representative RSNs: the anterior default mode network (left middle frontal gyrus), which is considered to be correlated with impaired social cognition, the somatosensory network (bilateral supplementary motor area and right postcentral gyrus), the lateral visual network (left superior occipital gyrus), and the medial visual network (right fusiform, left lingual gyrus and right calcarine), which are expected to be relevant to the perceptual systems responsible for perceptual dysfunction in male adolescents with CD. Importantly, the novel findings suggested that male adolescents with pure CD were identified to have dysfunctions in both low-level perceptual networks (the somatosensory network and visual network) and a high-order cognitive network (the default mode network). Revealing the changes in the functional connectivity of these RSNs enhances our understanding of the neural mechanisms underlying the modulation of emotion and social cognition and the regulation of perception in adolescents with CD. PMID:26713867

  12. Hierarchical organization of macaque and cat cortical sensory systems explored with a novel network processor.

    PubMed

    Hilgetag, C C; O'Neill, M A; Young, M P

    2000-01-29

    Neuroanatomists have described a large number of connections between the various structures of monkey and cat cortical sensory systems. Because of the complexity of the connection data, analysis is required to unravel what principles of organization they imply. To date, analysis of laminar origin and termination connection data to reveal hierarchical relationships between the cortical areas has been the most widely acknowledged approach. We programmed a network processor that searches for optimal hierarchical orderings of cortical areas given known hierarchical constraints and rules for their interpretation. For all cortical systems and all cost functions, the processor found a multitude of equally low-cost hierarchies. Laminar hierarchical constraints that are presently available in the anatomical literature were therefore insufficient to constrain a unique ordering for any of the sensory systems we analysed. Hierarchical orderings of the monkey visual system that have been widely reported, but which were derived by hand, were not among the optimal orderings. All the cortical systems we studied displayed a significant degree of hierarchical organization, and the anatomical constraints from the monkey visual and somato-motor systems were satisfied with very few constraint violations in the optimal hierarchies. The visual and somato-motor systems in that animal were therefore surprisingly strictly hierarchical. Most inconsistencies between the constraints and the hierarchical relationships in the optimal structures for the visual system were related to connections of area FST (fundus of superior temporal sulcus). We found that the hierarchical solutions could be further improved by assuming that FST consists of two areas, which differ in the nature of their projections. Indeed, we found that perfect hierarchical arrangements of the primate visual system, without any violation of anatomical constraints, could be obtained under two reasonable conditions, namely the subdivision of FST into two distinct areas, whose connectivity we predict, and the abolition of at least one of the less reliable rule constraints. Our analyses showed that the future collection of the same type of laminar constraints, or the inclusion of new hierarchical constraints from thalamocortical connections, will not resolve the problem of multiple optimal hierarchical representations for the primate visual system. Further data, however, may help to specify the relative ordering of some more areas. This indeterminacy of the visual hierarchy is in part due to the reported absence of some connections between cortical areas. These absences are consistent with limited cross-talk between differentiated processing streams in the system. Hence, hierarchical representation of the visual system is affected by, and must take into account, other organizational features, such as processing streams.

  13. The evaluative imaging of mental models - Visual representations of complexity

    NASA Technical Reports Server (NTRS)

    Dede, Christopher

    1989-01-01

    The paper deals with some design issues involved in building a system that could visually represent the semantic structures of training materials and their underlying mental models. In particular, hypermedia-based semantic networks that instantiate classification problem solving strategies are thought to be a useful formalism for such representations; the complexity of these web structures can be best managed through visual depictions. It is also noted that a useful approach to implement in these hypermedia models would be some metrics of conceptual distance.

  14. Communications Effects Server (CES) Model for Systems Engineering Research

    DTIC Science & Technology

    2012-01-31

    Visualization Tool Interface «logical» HLA Tool Interface «logical» DIS Tool Interface «logical» STK Tool Interface «module» Execution Kernels «logical...interoperate with STK when running simulations. GUI Components  Architect – The Architect represents the main network design and visualization ...interest» CES «block» Third Party Visualization Tool «block» Third Party Analysis Tool «block» Third Party Text Editor «block» HLA Tools Analyst User Army

  15. Note: Design and development of wireless controlled aerosol sampling network for large scale aerosol dispersion experiments.

    PubMed

    Gopalakrishnan, V; Subramanian, V; Baskaran, R; Venkatraman, B

    2015-07-01

    Wireless based custom built aerosol sampling network is designed, developed, and implemented for environmental aerosol sampling. These aerosol sampling systems are used in field measurement campaign, in which sodium aerosol dispersion experiments have been conducted as a part of environmental impact studies related to sodium cooled fast reactor. The sampling network contains 40 aerosol sampling units and each contains custom built sampling head and the wireless control networking designed with Programmable System on Chip (PSoC™) and Xbee Pro RF modules. The base station control is designed using graphical programming language LabView. The sampling network is programmed to operate in a preset time and the running status of the samplers in the network is visualized from the base station. The system is developed in such a way that it can be used for any other environment sampling system deployed in wide area and uneven terrain where manual operation is difficult due to the requirement of simultaneous operation and status logging.

  16. Note: Design and development of wireless controlled aerosol sampling network for large scale aerosol dispersion experiments

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gopalakrishnan, V.; Subramanian, V.; Baskaran, R.

    2015-07-15

    Wireless based custom built aerosol sampling network is designed, developed, and implemented for environmental aerosol sampling. These aerosol sampling systems are used in field measurement campaign, in which sodium aerosol dispersion experiments have been conducted as a part of environmental impact studies related to sodium cooled fast reactor. The sampling network contains 40 aerosol sampling units and each contains custom built sampling head and the wireless control networking designed with Programmable System on Chip (PSoC™) and Xbee Pro RF modules. The base station control is designed using graphical programming language LabView. The sampling network is programmed to operate in amore » preset time and the running status of the samplers in the network is visualized from the base station. The system is developed in such a way that it can be used for any other environment sampling system deployed in wide area and uneven terrain where manual operation is difficult due to the requirement of simultaneous operation and status logging.« less

  17. CoryneRegNet 3.0--an interactive systems biology platform for the analysis of gene regulatory networks in corynebacteria and Escherichia coli.

    PubMed

    Baumbach, Jan; Wittkop, Tobias; Rademacher, Katrin; Rahmann, Sven; Brinkrolf, Karina; Tauch, Andreas

    2007-04-30

    CoryneRegNet is an ontology-based data warehouse for the reconstruction and visualization of transcriptional regulatory interactions in prokaryotes. To extend the biological content of CoryneRegNet, we added comprehensive data on transcriptional regulations in the model organism Escherichia coli K-12, originally deposited in the international reference database RegulonDB. The enhanced web interface of CoryneRegNet offers several types of search options. The results of a search are displayed in a table-based style and include a visualization of the genetic organization of the respective gene region. Information on DNA binding sites of transcriptional regulators is depicted by sequence logos. The results can also be displayed by several layouters implemented in the graphical user interface GraphVis, allowing, for instance, the visualization of genome-wide network reconstructions and the homology-based inter-species comparison of reconstructed gene regulatory networks. In an application example, we compare the composition of the gene regulatory networks involved in the SOS response of E. coli and Corynebacterium glutamicum. CoryneRegNet is available at the following URL: http://www.cebitec.uni-bielefeld.de/groups/gi/software/coryneregnet/.

  18. Honeycomb: Visual Analysis of Large Scale Social Networks

    NASA Astrophysics Data System (ADS)

    van Ham, Frank; Schulz, Hans-Jörg; Dimicco, Joan M.

    The rise in the use of social network sites allows us to collect large amounts of user reported data on social structures and analysis of this data could provide useful insights for many of the social sciences. This analysis is typically the domain of Social Network Analysis, and visualization of these structures often proves invaluable in understanding them. However, currently available visual analysis tools are not very well suited to handle the massive scale of this network data, and often resolve to displaying small ego networks or heavily abstracted networks. In this paper, we present Honeycomb, a visualization tool that is able to deal with much larger scale data (with millions of connections), which we illustrate by using a large scale corporate social networking site as an example. Additionally, we introduce a new probability based network metric to guide users to potentially interesting or anomalous patterns and discuss lessons learned during design and implementation.

  19. Network activity influences the subthreshold and spiking visual responses of pyramidal neurons in the three-layer turtle cortex.

    PubMed

    Wright, Nathaniel C; Wessel, Ralf

    2017-10-01

    A primary goal of systems neuroscience is to understand cortical function, typically by studying spontaneous and stimulus-modulated cortical activity. Mounting evidence suggests a strong and complex relationship exists between the ongoing and stimulus-modulated cortical state. To date, most work in this area has been based on spiking in populations of neurons. While advantageous in many respects, this approach is limited in scope: it records the activity of a minority of neurons and gives no direct indication of the underlying subthreshold dynamics. Membrane potential recordings can fill these gaps in our understanding, but stable recordings are difficult to obtain in vivo. Here, we recorded subthreshold cortical visual responses in the ex vivo turtle eye-attached whole brain preparation, which is ideally suited for such a study. We found that, in the absence of visual stimulation, the network was "synchronous"; neurons displayed network-mediated transitions between hyperpolarized (Down) and depolarized (Up) membrane potential states. The prevalence of these slow-wave transitions varied across turtles and recording sessions. Visual stimulation evoked similar Up states, which were on average larger and less reliable when the ongoing state was more synchronous. Responses were muted when immediately preceded by large, spontaneous Up states. Evoked spiking was sparse, highly variable across trials, and mediated by concerted synaptic inputs that were, in general, only very weakly correlated with inputs to nearby neurons. Together, these results highlight the multiplexed influence of the cortical network on the spontaneous and sensory-evoked activity of individual cortical neurons. NEW & NOTEWORTHY Most studies of cortical activity focus on spikes. Subthreshold membrane potential recordings can provide complementary insight, but stable recordings are difficult to obtain in vivo. Here, we recorded the membrane potentials of cortical neurons during ongoing and visually evoked activity. We observed a strong relationship between network and single-neuron evoked activity spanning multiple temporal scales. The membrane potential perspective of cortical dynamics thus highlights the influence of intrinsic network properties on visual processing. Copyright © 2017 the American Physiological Society.

  20. PyPathway: Python Package for Biological Network Analysis and Visualization.

    PubMed

    Xu, Yang; Luo, Xiao-Chun

    2018-05-01

    Life science studies represent one of the biggest generators of large data sets, mainly because of rapid sequencing technological advances. Biological networks including interactive networks and human curated pathways are essential to understand these high-throughput data sets. Biological network analysis offers a method to explore systematically not only the molecular complexity of a particular disease but also the molecular relationships among apparently distinct phenotypes. Currently, several packages for Python community have been developed, such as BioPython and Goatools. However, tools to perform comprehensive network analysis and visualization are still needed. Here, we have developed PyPathway, an extensible free and open source Python package for functional enrichment analysis, network modeling, and network visualization. The network process module supports various interaction network and pathway databases such as Reactome, WikiPathway, STRING, and BioGRID. The network analysis module implements overrepresentation analysis, gene set enrichment analysis, network-based enrichment, and de novo network modeling. Finally, the visualization and data publishing modules enable users to share their analysis by using an easy web application. For package availability, see the first Reference.

  1. Mechanisms of Photoreceptor Patterning in Vertebrates and Invertebrates.

    PubMed

    Viets, Kayla; Eldred, Kiara; Johnston, Robert J

    2016-10-01

    Across the animal kingdom, visual systems have evolved to be uniquely suited to the environments and behavioral patterns of different species. Visual acuity and color perception depend on the distribution of photoreceptor (PR) subtypes within the retina. Retinal mosaics can be organized into three broad categories: stochastic/regionalized, regionalized, and ordered. We describe here the retinal mosaics of flies, zebrafish, chickens, mice, and humans, and the gene regulatory networks controlling proper PR specification in each. By drawing parallels in eye development between these divergent species, we identify a set of conserved organizing principles and transcriptional networks that govern PR subtype differentiation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. Mechanisms of photoreceptor patterning in vertebrates and invertebrates

    PubMed Central

    Johnston, Robert J

    2016-01-01

    Across the animal kingdom, visual systems have evolved to be uniquely suited to the environments and behavioral patterns of different species. The visual acuity and color perception of organisms depend on the distribution of photoreceptor subtypes within the retina. Retinal mosaics can be organized into three broad categories: stochastic/regionalized, regionalized, and ordered. Here, we describe the retinal mosaics of flies, zebrafish, chickens, mice, and humans and the gene regulatory networks controlling proper photoreceptor specification in each. By drawing parallels in eye development between these divergent species, we identify a set of conserved organizing principles and transcriptional networks that govern photoreceptor subtype differentiation. PMID:27615122

  3. Contrast adaptation in the Limulus lateral eye.

    PubMed

    Valtcheva, Tchoudomira M; Passaglia, Christopher L

    2015-12-01

    Luminance and contrast adaptation are neuronal mechanisms employed by the visual system to adjust our sensitivity to light. They are mediated by an assortment of cellular and network processes distributed across the retina and visual cortex. Both have been demonstrated in the eyes of many vertebrates, but only luminance adaptation has been shown in invertebrate eyes to date. Since the computational benefits of contrast adaptation should apply to all visual systems, we investigated whether this mechanism operates in horseshoe crab eyes, one of the best-understood neural networks in the animal kingdom. The spike trains of optic nerve fibers were recorded in response to light stimuli modulated randomly in time and delivered to single ommatidia or the whole eye. We found that the retina adapts to both the mean luminance and contrast of a white-noise stimulus, that luminance- and contrast-adaptive processes are largely independent, and that they originate within an ommatidium. Network interactions are not involved. A published computer model that simulates existing knowledge of the horseshoe crab eye did not show contrast adaptation, suggesting that a heretofore unknown mechanism may underlie the phenomenon. This mechanism does not appear to reside in photoreceptors because white-noise analysis of electroretinogram recordings did not show contrast adaptation. The likely site of origin is therefore the spike discharge mechanism of optic nerve fibers. The finding of contrast adaption in a retinal network as simple as the horseshoe crab eye underscores the broader importance of this image processing strategy to vision. Copyright © 2015 the American Physiological Society.

  4. Contrast adaptation in the Limulus lateral eye

    PubMed Central

    Valtcheva, Tchoudomira M.

    2015-01-01

    Luminance and contrast adaptation are neuronal mechanisms employed by the visual system to adjust our sensitivity to light. They are mediated by an assortment of cellular and network processes distributed across the retina and visual cortex. Both have been demonstrated in the eyes of many vertebrates, but only luminance adaptation has been shown in invertebrate eyes to date. Since the computational benefits of contrast adaptation should apply to all visual systems, we investigated whether this mechanism operates in horseshoe crab eyes, one of the best-understood neural networks in the animal kingdom. The spike trains of optic nerve fibers were recorded in response to light stimuli modulated randomly in time and delivered to single ommatidia or the whole eye. We found that the retina adapts to both the mean luminance and contrast of a white-noise stimulus, that luminance- and contrast-adaptive processes are largely independent, and that they originate within an ommatidium. Network interactions are not involved. A published computer model that simulates existing knowledge of the horseshoe crab eye did not show contrast adaptation, suggesting that a heretofore unknown mechanism may underlie the phenomenon. This mechanism does not appear to reside in photoreceptors because white-noise analysis of electroretinogram recordings did not show contrast adaptation. The likely site of origin is therefore the spike discharge mechanism of optic nerve fibers. The finding of contrast adaption in a retinal network as simple as the horseshoe crab eye underscores the broader importance of this image processing strategy to vision. PMID:26445869

  5. A Prototype Visualization of Real-time River Drainage Network Response to Rainfall

    NASA Astrophysics Data System (ADS)

    Demir, I.; Krajewski, W. F.

    2011-12-01

    The Iowa Flood Information System (IFIS) is a web-based platform developed by the Iowa Flood Center (IFC) to provide access to and visualization of flood inundation maps, real-time flood conditions, flood forecasts both short-term and seasonal, and other flood-related data for communities in Iowa. The key element of the system's architecture is the notion of community. Locations of the communities, those near streams and rivers, define basin boundaries. The IFIS streams rainfall data from NEXRAD radar, and provides three interfaces including animation for rainfall intensity, daily rainfall totals and rainfall accumulations for past 14 days for Iowa. A real-time interactive visualization interface is developed using past rainfall intensity data. The interface creates community-based rainfall products on-demand using watershed boundaries of each community as a mask. Each individual rainfall pixel is tracked in the interface along the drainage network, and the ones drains to same pixel location are accumulated. The interface loads recent rainfall data in five minute intervals that are combined with current values. Latest web technologies are utilized for the development of the interface including HTML 5 Canvas, and JavaScript. The performance of the interface is optimized to run smoothly on modern web browsers. The interface controls allow users to change internal parameters of the system, and operation conditions of the animation. The interface will help communities understand the effects of rainfall on water transport in stream and river networks and make better-informed decisions regarding the threat of floods. This presentation provides an overview of a unique visualization interface and discusses future plans for real-time dynamic presentations of streamflow forecasting.

  6. A Web-based Data Intensive Visualization of Real-time River Drainage Network Response to Rainfall

    NASA Astrophysics Data System (ADS)

    Demir, I.; Krajewski, W. F.

    2012-04-01

    The Iowa Flood Information System (IFIS) is a web-based platform developed by the Iowa Flood Center (IFC) to provide access to and visualization of flood inundation maps, real-time flood conditions, flood forecasts both short-term and seasonal, and other flood-related data for communities in Iowa. The key element of the system's architecture is the notion of community. Locations of the communities, those near streams and rivers, define basin boundaries. The IFIS streams rainfall data from NEXRAD radar, and provides three interfaces including animation for rainfall intensity, daily rainfall totals and rainfall accumulations for past 14 days for Iowa. A real-time interactive visualization interface is developed using past rainfall intensity data. The interface creates community-based rainfall products on-demand using watershed boundaries of each community as a mask. Each individual rainfall pixel is tracked in the interface along the drainage network, and the ones drains to same pixel location are accumulated. The interface loads recent rainfall data in five minute intervals that are combined with current values. Latest web technologies are utilized for the development of the interface including HTML 5 Canvas, and JavaScript. The performance of the interface is optimized to run smoothly on modern web browsers. The interface controls allow users to change internal parameters of the system, and operation conditions of the animation. The interface will help communities understand the effects of rainfall on water transport in stream and river networks and make better-informed decisions regarding the threat of floods. This presentation provides an overview of a unique visualization interface and discusses future plans for real-time dynamic presentations of streamflow forecasting.

  7. PRODIGEN: visualizing the probability landscape of stochastic gene regulatory networks in state and time space.

    PubMed

    Ma, Chihua; Luciani, Timothy; Terebus, Anna; Liang, Jie; Marai, G Elisabeta

    2017-02-15

    Visualizing the complex probability landscape of stochastic gene regulatory networks can further biologists' understanding of phenotypic behavior associated with specific genes. We present PRODIGEN (PRObability DIstribution of GEne Networks), a web-based visual analysis tool for the systematic exploration of probability distributions over simulation time and state space in such networks. PRODIGEN was designed in collaboration with bioinformaticians who research stochastic gene networks. The analysis tool combines in a novel way existing, expanded, and new visual encodings to capture the time-varying characteristics of probability distributions: spaghetti plots over one dimensional projection, heatmaps of distributions over 2D projections, enhanced with overlaid time curves to display temporal changes, and novel individual glyphs of state information corresponding to particular peaks. We demonstrate the effectiveness of the tool through two case studies on the computed probabilistic landscape of a gene regulatory network and of a toggle-switch network. Domain expert feedback indicates that our visual approach can help biologists: 1) visualize probabilities of stable states, 2) explore the temporal probability distributions, and 3) discover small peaks in the probability landscape that have potential relation to specific diseases.

  8. A survey on sensor coverage and visual data capturing/processing/transmission in wireless visual sensor networks.

    PubMed

    Yap, Florence G H; Yen, Hong-Hsu

    2014-02-20

    Wireless Visual Sensor Networks (WVSNs) where camera-equipped sensor nodes can capture, process and transmit image/video information have become an important new research area. As compared to the traditional wireless sensor networks (WSNs) that can only transmit scalar information (e.g., temperature), the visual data in WVSNs enable much wider applications, such as visual security surveillance and visual wildlife monitoring. However, as compared to the scalar data in WSNs, visual data is much bigger and more complicated so intelligent schemes are required to capture/process/ transmit visual data in limited resources (hardware capability and bandwidth) WVSNs. WVSNs introduce new multi-disciplinary research opportunities of topics that include visual sensor hardware, image and multimedia capture and processing, wireless communication and networking. In this paper, we survey existing research efforts on the visual sensor hardware, visual sensor coverage/deployment, and visual data capture/ processing/transmission issues in WVSNs. We conclude that WVSN research is still in an early age and there are still many open issues that have not been fully addressed. More new novel multi-disciplinary, cross-layered, distributed and collaborative solutions should be devised to tackle these challenging issues in WVSNs.

  9. A Survey on Sensor Coverage and Visual Data Capturing/Processing/Transmission in Wireless Visual Sensor Networks

    PubMed Central

    Yap, Florence G. H.; Yen, Hong-Hsu

    2014-01-01

    Wireless Visual Sensor Networks (WVSNs) where camera-equipped sensor nodes can capture, process and transmit image/video information have become an important new research area. As compared to the traditional wireless sensor networks (WSNs) that can only transmit scalar information (e.g., temperature), the visual data in WVSNs enable much wider applications, such as visual security surveillance and visual wildlife monitoring. However, as compared to the scalar data in WSNs, visual data is much bigger and more complicated so intelligent schemes are required to capture/process/transmit visual data in limited resources (hardware capability and bandwidth) WVSNs. WVSNs introduce new multi-disciplinary research opportunities of topics that include visual sensor hardware, image and multimedia capture and processing, wireless communication and networking. In this paper, we survey existing research efforts on the visual sensor hardware, visual sensor coverage/deployment, and visual data capture/processing/transmission issues in WVSNs. We conclude that WVSN research is still in an early age and there are still many open issues that have not been fully addressed. More new novel multi-disciplinary, cross-layered, distributed and collaborative solutions should be devised to tackle these challenging issues in WVSNs. PMID:24561401

  10. Building University Capacity to Visualize Solutions to Complex Problems in the Arctic

    NASA Astrophysics Data System (ADS)

    Broderson, D.; Veazey, P.; Raymond, V. L.; Kowalski, K.; Prakash, A.; Signor, B.

    2016-12-01

    Rapidly changing environments are creating complex problems across the globe, which are particular magnified in the Arctic. These worldwide challenges can best be addressed through diverse and interdisciplinary research teams. It is incumbent on such teams to promote co-production of knowledge and data-driven decision-making by identifying effective methods to communicate their findings and to engage with the public. Decision Theater North (DTN) is a new semi-immersive visualization system that provides a space for teams to collaborate and develop solutions to complex problems, relying on diverse sets of skills and knowledge. It provides a venue to synthesize the talents of scientists, who gather information (data); modelers, who create models of complex systems; artists, who develop visualizations; communicators, who connect and bridge populations; and policymakers, who can use the visualizations to develop sustainable solutions to pressing problems. The mission of Decision Theater North is to provide a cutting-edge visual environment to facilitate dialogue and decision-making by stakeholders including government, industry, communities and academia. We achieve this mission by adopting a multi-faceted approach reflected in the theater's design, technology, networking capabilities, user support, community relationship building, and strategic partnerships. DTN is a joint project of Alaska's National Science Foundation Experimental Program to Stimulate Competitive Research (NSF EPSCoR) and the University of Alaska Fairbanks (UAF), who have brought the facility up to full operational status and are now expanding its development space to support larger team science efforts. Based in Fairbanks, Alaska, DTN is uniquely poised to address changes taking place in the Arctic and subarctic, and is connected with a larger network of decision theaters that include the Arizona State University Decision Theater Network and the McCain Institute in Washington, DC.

  11. General visual robot controller networks via artificial evolution

    NASA Astrophysics Data System (ADS)

    Cliff, David; Harvey, Inman; Husbands, Philip

    1993-08-01

    We discuss recent results from our ongoing research concerning the application of artificial evolution techniques (i.e., an extended form of genetic algorithm) to the problem of developing `neural' network controllers for visually guided robots. The robot is a small autonomous vehicle with extremely low-resolution vision, employing visual sensors which could readily be constructed from discrete analog components. In addition to visual sensing, the robot is equipped with a small number of mechanical tactile sensors. Activity from the sensors is fed to a recurrent dynamical artificial `neural' network, which acts as the robot controller, providing signals to motors governing the robot's motion. Prior to presentation of new results, this paper summarizes our rationale and past work, which has demonstrated that visually guided control networks can arise without any explicit specification that visual processing should be employed: the evolutionary process opportunistically makes use of visual information if it is available.

  12. Real time unsupervised learning of visual stimuli in neuromorphic VLSI systems

    PubMed Central

    Giulioni, Massimiliano; Corradi, Federico; Dante, Vittorio; del Giudice, Paolo

    2015-01-01

    Neuromorphic chips embody computational principles operating in the nervous system, into microelectronic devices. In this domain it is important to identify computational primitives that theory and experiments suggest as generic and reusable cognitive elements. One such element is provided by attractor dynamics in recurrent networks. Point attractors are equilibrium states of the dynamics (up to fluctuations), determined by the synaptic structure of the network; a ‘basin’ of attraction comprises all initial states leading to a given attractor upon relaxation, hence making attractor dynamics suitable to implement robust associative memory. The initial network state is dictated by the stimulus, and relaxation to the attractor state implements the retrieval of the corresponding memorized prototypical pattern. In a previous work we demonstrated that a neuromorphic recurrent network of spiking neurons and suitably chosen, fixed synapses supports attractor dynamics. Here we focus on learning: activating on-chip synaptic plasticity and using a theory-driven strategy for choosing network parameters, we show that autonomous learning, following repeated presentation of simple visual stimuli, shapes a synaptic connectivity supporting stimulus-selective attractors. Associative memory develops on chip as the result of the coupled stimulus-driven neural activity and ensuing synaptic dynamics, with no artificial separation between learning and retrieval phases. PMID:26463272

  13. A Visual Analytics Approach for Station-Based Air Quality Data

    PubMed Central

    Du, Yi; Ma, Cuixia; Wu, Chao; Xu, Xiaowei; Guo, Yike; Zhou, Yuanchun; Li, Jianhui

    2016-01-01

    With the deployment of multi-modality and large-scale sensor networks for monitoring air quality, we are now able to collect large and multi-dimensional spatio-temporal datasets. For these sensed data, we present a comprehensive visual analysis approach for air quality analysis. This approach integrates several visual methods, such as map-based views, calendar views, and trends views, to assist the analysis. Among those visual methods, map-based visual methods are used to display the locations of interest, and the calendar and the trends views are used to discover the linear and periodical patterns. The system also provides various interaction tools to combine the map-based visualization, trends view, calendar view and multi-dimensional view. In addition, we propose a self-adaptive calendar-based controller that can flexibly adapt the changes of data size and granularity in trends view. Such a visual analytics system would facilitate big-data analysis in real applications, especially for decision making support. PMID:28029117

  14. A Visual Analytics Approach for Station-Based Air Quality Data.

    PubMed

    Du, Yi; Ma, Cuixia; Wu, Chao; Xu, Xiaowei; Guo, Yike; Zhou, Yuanchun; Li, Jianhui

    2016-12-24

    With the deployment of multi-modality and large-scale sensor networks for monitoring air quality, we are now able to collect large and multi-dimensional spatio-temporal datasets. For these sensed data, we present a comprehensive visual analysis approach for air quality analysis. This approach integrates several visual methods, such as map-based views, calendar views, and trends views, to assist the analysis. Among those visual methods, map-based visual methods are used to display the locations of interest, and the calendar and the trends views are used to discover the linear and periodical patterns. The system also provides various interaction tools to combine the map-based visualization, trends view, calendar view and multi-dimensional view. In addition, we propose a self-adaptive calendar-based controller that can flexibly adapt the changes of data size and granularity in trends view. Such a visual analytics system would facilitate big-data analysis in real applications, especially for decision making support.

  15. A Fuzzy-Based Approach for Sensing, Coding and Transmission Configuration of Visual Sensors in Smart City Applications

    PubMed Central

    Costa, Daniel G.; Collotta, Mario; Pau, Giovanni; Duran-Faundez, Cristian

    2017-01-01

    The advance of technologies in several areas has allowed the development of smart city applications, which can improve the way of life in modern cities. When employing visual sensors in that scenario, still images and video streams may be retrieved from monitored areas, potentially providing valuable data for many applications. Actually, visual sensor networks may need to be highly dynamic, reflecting the changing of parameters in smart cities. In this context, characteristics of visual sensors and conditions of the monitored environment, as well as the status of other concurrent monitoring systems, may affect how visual sensors collect, encode and transmit information. This paper proposes a fuzzy-based approach to dynamically configure the way visual sensors will operate concerning sensing, coding and transmission patterns, exploiting different types of reference parameters. This innovative approach can be considered as the basis for multi-systems smart city applications based on visual monitoring, potentially bringing significant results for this research field. PMID:28067777

  16. A Fuzzy-Based Approach for Sensing, Coding and Transmission Configuration of Visual Sensors in Smart City Applications.

    PubMed

    Costa, Daniel G; Collotta, Mario; Pau, Giovanni; Duran-Faundez, Cristian

    2017-01-05

    The advance of technologies in several areas has allowed the development of smart city applications, which can improve the way of life in modern cities. When employing visual sensors in that scenario, still images and video streams may be retrieved from monitored areas, potentially providing valuable data for many applications. Actually, visual sensor networks may need to be highly dynamic, reflecting the changing of parameters in smart cities. In this context, characteristics of visual sensors and conditions of the monitored environment, as well as the status of other concurrent monitoring systems, may affect how visual sensors collect, encode and transmit information. This paper proposes a fuzzy-based approach to dynamically configure the way visual sensors will operate concerning sensing, coding and transmission patterns, exploiting different types of reference parameters. This innovative approach can be considered as the basis for multi-systems smart city applications based on visual monitoring, potentially bringing significant results for this research field.

  17. The emergence of polychronization and feature binding in a spiking neural network model of the primate ventral visual system.

    PubMed

    Eguchi, Akihiro; Isbister, James B; Ahmad, Nasir; Stringer, Simon

    2018-07-01

    We present a hierarchical neural network model, in which subpopulations of neurons develop fixed and regularly repeating temporal chains of spikes (polychronization), which respond specifically to randomized Poisson spike trains representing the input training images. The performance is improved by including top-down and lateral synaptic connections, as well as introducing multiple synaptic contacts between each pair of pre- and postsynaptic neurons, with different synaptic contacts having different axonal delays. Spike-timing-dependent plasticity thus allows the model to select the most effective axonal transmission delay between neurons. Furthermore, neurons representing the binding relationship between low-level and high-level visual features emerge through visually guided learning. This begins to provide a way forward to solving the classic feature binding problem in visual neuroscience and leads to a new hypothesis concerning how information about visual features at every spatial scale may be projected upward through successive neuronal layers. We name this hypothetical upward projection of information the "holographic principle." (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  18. Grohar: Automated Visualization of Genome-Scale Metabolic Models and Their Pathways.

    PubMed

    Moškon, Miha; Zimic, Nikolaj; Mraz, Miha

    2018-05-01

    Genome-scale metabolic models (GEMs) have become a powerful tool for the investigation of the entire metabolism of the organism in silico. These models are, however, often extremely hard to reconstruct and also difficult to apply to the selected problem. Visualization of the GEM allows us to easier comprehend the model, to perform its graphical analysis, to find and correct the faulty relations, to identify the parts of the system with a designated function, etc. Even though several approaches for the automatic visualization of GEMs have been proposed, metabolic maps are still manually drawn or at least require large amount of manual curation. We present Grohar, a computational tool for automatic identification and visualization of GEM (sub)networks and their metabolic fluxes. These (sub)networks can be specified directly by listing the metabolites of interest or indirectly by providing reference metabolic pathways from different sources, such as KEGG, SBML, or Matlab file. These pathways are identified within the GEM using three different pathway alignment algorithms. Grohar also supports the visualization of the model adjustments (e.g., activation or inhibition of metabolic reactions) after perturbations are induced.

  19. How Deep Neural Networks Can Improve Emotion Recognition on Video Data

    DTIC Science & Technology

    2016-09-25

    HOW DEEP NEURAL NETWORKS CAN IMPROVE EMOTION RECOGNITION ON VIDEO DATA Pooya Khorrami1 , Tom Le Paine1, Kevin Brady2, Charlie Dagli2, Thomas S...this work, we present a system that per- forms emotion recognition on video data using both con- volutional neural networks (CNNs) and recurrent...neural net- works (RNNs). We present our findings on videos from the Audio/Visual+Emotion Challenge (AV+EC2015). In our experiments, we analyze the effects

  20. Network Physiology: How Organ Systems Dynamically Interact

    PubMed Central

    Bartsch, Ronny P.; Liu, Kang K. L.; Bashan, Amir; Ivanov, Plamen Ch.

    2015-01-01

    We systematically study how diverse physiologic systems in the human organism dynamically interact and collectively behave to produce distinct physiologic states and functions. This is a fundamental question in the new interdisciplinary field of Network Physiology, and has not been previously explored. Introducing the novel concept of Time Delay Stability (TDS), we develop a computational approach to identify and quantify networks of physiologic interactions from long-term continuous, multi-channel physiological recordings. We also develop a physiologically-motivated visualization framework to map networks of dynamical organ interactions to graphical objects encoded with information about the coupling strength of network links quantified using the TDS measure. Applying a system-wide integrative approach, we identify distinct patterns in the network structure of organ interactions, as well as the frequency bands through which these interactions are mediated. We establish first maps representing physiologic organ network interactions and discover basic rules underlying the complex hierarchical reorganization in physiologic networks with transitions across physiologic states. Our findings demonstrate a direct association between network topology and physiologic function, and provide new insights into understanding how health and distinct physiologic states emerge from networked interactions among nonlinear multi-component complex systems. The presented here investigations are initial steps in building a first atlas of dynamic interactions among organ systems. PMID:26555073

  1. Visual feature extraction and establishment of visual tags in the intelligent visual internet of things

    NASA Astrophysics Data System (ADS)

    Zhao, Yiqun; Wang, Zhihui

    2015-12-01

    The Internet of things (IOT) is a kind of intelligent networks which can be used to locate, track, identify and supervise people and objects. One of important core technologies of intelligent visual internet of things ( IVIOT) is the intelligent visual tag system. In this paper, a research is done into visual feature extraction and establishment of visual tags of the human face based on ORL face database. Firstly, we use the principal component analysis (PCA) algorithm for face feature extraction, then adopt the support vector machine (SVM) for classifying and face recognition, finally establish a visual tag for face which is already classified. We conducted a experiment focused on a group of people face images, the result show that the proposed algorithm have good performance, and can show the visual tag of objects conveniently.

  2. Functional network connectivity underlying food processing: disturbed salience and visual processing in overweight and obese adults.

    PubMed

    Kullmann, Stephanie; Pape, Anna-Antonia; Heni, Martin; Ketterer, Caroline; Schick, Fritz; Häring, Hans-Ulrich; Fritsche, Andreas; Preissl, Hubert; Veit, Ralf

    2013-05-01

    In order to adequately explore the neurobiological basis of eating behavior of humans and their changes with body weight, interactions between brain areas or networks need to be investigated. In the current functional magnetic resonance imaging study, we examined the modulating effects of stimulus category (food vs. nonfood), caloric content of food, and body weight on the time course and functional connectivity of 5 brain networks by means of independent component analysis in healthy lean and overweight/obese adults. These functional networks included motor sensory, default-mode, extrastriate visual, temporal visual association, and salience networks. We found an extensive modulation elicited by food stimuli in the 2 visual and salience networks, with a dissociable pattern in the time course and functional connectivity between lean and overweight/obese subjects. Specifically, only in lean subjects, the temporal visual association network was modulated by the stimulus category and the salience network by caloric content, whereas overweight and obese subjects showed a generalized augmented response in the salience network. Furthermore, overweight/obese subjects showed changes in functional connectivity in networks important for object recognition, motivational salience, and executive control. These alterations could potentially lead to top-down deficiencies driving the overconsumption of food in the obese population.

  3. Altered intra- and inter-network functional coupling of resting-state networks associated with motor dysfunction in stroke.

    PubMed

    Zhao, Zhiyong; Wu, Jie; Fan, Mingxia; Yin, Dazhi; Tang, Chaozheng; Gong, Jiayu; Xu, Guojun; Gao, Xinjie; Yu, Qiurong; Yang, Hao; Sun, Limin; Jia, Jie

    2018-04-24

    Motor functions are supported through functional integration across the extended motor system network. Individuals following stroke often show deficits on motor performance requiring coordination of multiple brain networks; however, the assessment of connectivity patterns after stroke was still unclear. This study aimed to investigate the changes in intra- and inter-network functional connectivity (FC) of multiple networks following stroke and further correlate FC with motor performance. Thirty-three left subcortical chronic stroke patients and 34 healthy controls underwent resting-state functional magnetic resonance imaging. Eleven resting-state networks were identified via independent component analysis (ICA). Compared with healthy controls, the stroke group showed abnormal FC within the motor network (MN), visual network (VN), dorsal attention network (DAN), and executive control network (ECN). Additionally, the FC values of the ipsilesional inferior parietal lobule (IPL) within the ECN were negatively correlated with the Fugl-Meyer Assessment (FMA) scores (hand + wrist). With respect to inter-network interactions, the ipsilesional frontoparietal network (FPN) decreased FC with the MN and DAN; the contralesional FPN decreased FC with the ECN, but it increased FC with the default mode network (DMN); and the posterior DMN decreased FC with the VN. In sum, this study demonstrated the coexistence of intra- and inter-network alterations associated with motor-visual attention and high-order cognitive control function in chronic stroke, which might provide insights into brain network plasticity following stroke. © 2018 Wiley Periodicals, Inc.

  4. ModuleRole: a tool for modulization, role determination and visualization in protein-protein interaction networks.

    PubMed

    Li, Guipeng; Li, Ming; Zhang, Yiwei; Wang, Dong; Li, Rong; Guimerà, Roger; Gao, Juntao Tony; Zhang, Michael Q

    2014-01-01

    Rapidly increasing amounts of (physical and genetic) protein-protein interaction (PPI) data are produced by various high-throughput techniques, and interpretation of these data remains a major challenge. In order to gain insight into the organization and structure of the resultant large complex networks formed by interacting molecules, using simulated annealing, a method based on the node connectivity, we developed ModuleRole, a user-friendly web server tool which finds modules in PPI network and defines the roles for every node, and produces files for visualization in Cytoscape and Pajek. For given proteins, it analyzes the PPI network from BioGRID database, finds and visualizes the modules these proteins form, and then defines the role every node plays in this network, based on two topological parameters Participation Coefficient and Z-score. This is the first program which provides interactive and very friendly interface for biologists to find and visualize modules and roles of proteins in PPI network. It can be tested online at the website http://www.bioinfo.org/modulerole/index.php, which is free and open to all users and there is no login requirement, with demo data provided by "User Guide" in the menu Help. Non-server application of this program is considered for high-throughput data with more than 200 nodes or user's own interaction datasets. Users are able to bookmark the web link to the result page and access at a later time. As an interactive and highly customizable application, ModuleRole requires no expert knowledge in graph theory on the user side and can be used in both Linux and Windows system, thus a very useful tool for biologist to analyze and visualize PPI networks from databases such as BioGRID. ModuleRole is implemented in Java and C, and is freely available at http://www.bioinfo.org/modulerole/index.php. Supplementary information (user guide, demo data) is also available at this website. API for ModuleRole used for this program can be obtained upon request.

  5. Seamless Tracing of Human Behavior Using Complementary Wearable and House-Embedded Sensors

    PubMed Central

    Augustyniak, Piotr; Smoleń, Magdalena; Mikrut, Zbigniew; Kańtoch, Eliasz

    2014-01-01

    This paper presents a multimodal system for seamless surveillance of elderly people in their living environment. The system uses simultaneously a wearable sensor network for each individual and premise-embedded sensors specific for each environment. The paper demonstrates the benefits of using complementary information from two types of mobility sensors: visual flow-based image analysis and an accelerometer-based wearable network. The paper provides results for indoor recognition of several elementary poses and outdoor recognition of complex movements. Instead of complete system description, particular attention was drawn to a polar histogram-based method of visual pose recognition, complementary use and synchronization of the data from wearable and premise-embedded networks and an automatic danger detection algorithm driven by two premise- and subject-related databases. The novelty of our approach also consists in feeding the databases with real-life recordings from the subject, and in using the dynamic time-warping algorithm for measurements of distance between actions represented as elementary poses in behavioral records. The main results of testing our method include: 95.5% accuracy of elementary pose recognition by the video system, 96.7% accuracy of elementary pose recognition by the accelerometer-based system, 98.9% accuracy of elementary pose recognition by the combined accelerometer and video-based system, and 80% accuracy of complex outdoor activity recognition by the accelerometer-based wearable system. PMID:24787640

  6. Top-down control of visual perception: attention in natural vision.

    PubMed

    Rolls, Edmund T

    2008-01-01

    Top-down perceptual influences can bias (or pre-empt) perception. In natural scenes, the receptive fields of neurons in the inferior temporal visual cortex (IT) shrink to become close to the size of objects. This facilitates the read-out of information from the ventral visual system, because the information is primarily about the object at the fovea. Top-down attentional influences are much less evident in natural scenes than when objects are shown against blank backgrounds, though are still present. It is suggested that the reduced receptive-field size in natural scenes, and the effects of top-down attention contribute to change blindness. The receptive fields of IT neurons in complex scenes, though including the fovea, are frequently asymmetric around the fovea, and it is proposed that this is the solution the IT uses to represent multiple objects and their relative spatial positions in a scene. Networks that implement probabilistic decision-making are described, and it is suggested that, when in perceptual systems they take decisions (or 'test hypotheses'), they influence lower-level networks to bias visual perception. Finally, it is shown that similar processes extend to systems involved in the processing of emotion-provoking sensory stimuli, in that word-level cognitive states provide top-down biasing that reaches as far down as the orbitofrontal cortex, where, at the first stage of affective representations, olfactory, taste, flavour, and touch processing is biased (or pre-empted) in humans.

  7. The ventral visual pathway: An expanded neural framework for the processing of object quality

    PubMed Central

    Kravitz, Dwight J.; Saleem, Kadharbatcha S.; Baker, Chris I.; Ungerleider, Leslie G.; Mishkin, Mortimer

    2012-01-01

    Since the original characterization of the ventral visual pathway our knowledge of its neuroanatomy, functional properties, and extrinsic targets has grown considerably. Here we synthesize this recent evidence and propose that the ventral pathway is best understood as a recurrent occipitotemporal network containing neural representations of object quality both utilized and constrained by at least six distinct cortical and subcortical systems. Each system serves its own specialized behavioral, cognitive, or affective function, collectively providing the raison d’etre for the ventral visual pathway. This expanded framework contrasts with the depiction of the ventral visual pathway as a largely serial staged hierarchy that culminates in singular object representations for utilization mainly by ventrolateral prefrontal cortex and, more parsimoniously than this account, incorporates attentional, contextual, and feedback effects. PMID:23265839

  8. Organizational routines, innovation, and flexibility: the application of narrative networks to dynamic workflow.

    PubMed

    Hayes, Gillian R; Lee, Charlotte P; Dourish, Paul

    2011-08-01

    The purpose of this paper is to demonstrate how current visual representations of organizational and technological processes do not fully account for the variability present in everyday practices. We further demonstrate how narrative networks can augment these representations to indicate potential areas for successful or problematic adoption of new technologies and potential needs for additional training. We conducted a qualitative study of the processes and routines at a major academic medical center slated to be supported by the development and installation of a new comprehensive HIT system. We used qualitative data collection techniques including observations of the activities to be supported by the new system and interviews with department heads, researchers, and both clinical and non-clinical staff. We conducted a narrative network analysis of these data by choosing exemplar processes to be modeled, selecting and analyzing narrative fragments, and developing visual representations of the interconnection of these narratives. Narrative networks enable us to view the variety of ways work has been and can be performed in practice, influencing our ability to design for innovation in use. Narrative networks are a means for analyzing and visualizing organizational routines in concert with more traditional requirements engineering, workflow modeling, and quality improvement outcome measurement. This type of analysis can support a deeper and more nuanced understanding of how and why certain routines continue to exist, change, or stop entirely. At the same time, it can illuminate areas in which adoption may be slow, more training or communication may be needed, and routines preferred by the leadership are subverted by routines preferred by the staff. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  9. Causal biological network database: a comprehensive platform of causal biological network models focused on the pulmonary and vascular systems.

    PubMed

    Boué, Stéphanie; Talikka, Marja; Westra, Jurjen Willem; Hayes, William; Di Fabio, Anselmo; Park, Jennifer; Schlage, Walter K; Sewer, Alain; Fields, Brett; Ansari, Sam; Martin, Florian; Veljkovic, Emilija; Kenney, Renee; Peitsch, Manuel C; Hoeng, Julia

    2015-01-01

    With the wealth of publications and data available, powerful and transparent computational approaches are required to represent measured data and scientific knowledge in a computable and searchable format. We developed a set of biological network models, scripted in the Biological Expression Language, that reflect causal signaling pathways across a wide range of biological processes, including cell fate, cell stress, cell proliferation, inflammation, tissue repair and angiogenesis in the pulmonary and cardiovascular context. This comprehensive collection of networks is now freely available to the scientific community in a centralized web-based repository, the Causal Biological Network database, which is composed of over 120 manually curated and well annotated biological network models and can be accessed at http://causalbionet.com. The website accesses a MongoDB, which stores all versions of the networks as JSON objects and allows users to search for genes, proteins, biological processes, small molecules and keywords in the network descriptions to retrieve biological networks of interest. The content of the networks can be visualized and browsed. Nodes and edges can be filtered and all supporting evidence for the edges can be browsed and is linked to the original articles in PubMed. Moreover, networks may be downloaded for further visualization and evaluation. Database URL: http://causalbionet.com © The Author(s) 2015. Published by Oxford University Press.

  10. Visualizing Article Similarities via Sparsified Article Network and Map Projection for Systematic Reviews.

    PubMed

    Ji, Xiaonan; Machiraju, Raghu; Ritter, Alan; Yen, Po-Yin

    2017-01-01

    Systematic Reviews (SRs) of biomedical literature summarize evidence from high-quality studies to inform clinical decisions, but are time and labor intensive due to the large number of article collections. Article similarities established from textual features have been shown to assist in the identification of relevant articles, thus facilitating the article screening process efficiently. In this study, we visualized article similarities to extend its utilization in practical settings for SR researchers, aiming to promote human comprehension of article distributions and hidden patterns. To prompt an effective visualization in an interpretable, intuitive, and scalable way, we implemented a graph-based network visualization with three network sparsification approaches and a distance-based map projection via dimensionality reduction. We evaluated and compared three network sparsification approaches and the visualization types (article network vs. article map). We demonstrated the effectiveness in revealing article distribution and exhibiting clustering patterns of relevant articles with practical meanings for SRs.

  11. BIOLOGICAL NETWORK EXPLORATION WITH CYTOSCAPE 3

    PubMed Central

    Su, Gang; Morris, John H.; Demchak, Barry; Bader, Gary D.

    2014-01-01

    Cytoscape is one of the most popular open-source software tools for the visual exploration of biomedical networks composed of protein, gene and other types of interactions. It offers researchers a versatile and interactive visualization interface for exploring complex biological interconnections supported by diverse annotation and experimental data, thereby facilitating research tasks such as predicting gene function and pathway construction. Cytoscape provides core functionality to load, visualize, search, filter and save networks, and hundreds of Apps extend this functionality to address specific research needs. The latest generation of Cytoscape (version 3.0 and later) has substantial improvements in function, user interface and performance relative to previous versions. This protocol aims to jump-start new users with specific protocols for basic Cytoscape functions, such as installing Cytoscape and Cytoscape Apps, loading data, visualizing and navigating the network, visualizing network associated data (attributes) and identifying clusters. It also highlights new features that benefit experienced users. PMID:25199793

  12. Cross-frequency synchronization connects networks of fast and slow oscillations during visual working memory maintenance

    PubMed Central

    Siebenhühner, Felix; Wang, Sheng H; Palva, J Matias; Palva, Satu

    2016-01-01

    Neuronal activity in sensory and fronto-parietal (FP) areas underlies the representation and attentional control, respectively, of sensory information maintained in visual working memory (VWM). Within these regions, beta/gamma phase-synchronization supports the integration of sensory functions, while synchronization in theta/alpha bands supports the regulation of attentional functions. A key challenge is to understand which mechanisms integrate neuronal processing across these distinct frequencies and thereby the sensory and attentional functions. We investigated whether such integration could be achieved by cross-frequency phase synchrony (CFS). Using concurrent magneto- and electroencephalography, we found that CFS was load-dependently enhanced between theta and alpha–gamma and between alpha and beta-gamma oscillations during VWM maintenance among visual, FP, and dorsal attention (DA) systems. CFS also connected the hubs of within-frequency-synchronized networks and its strength predicted individual VWM capacity. We propose that CFS integrates processing among synchronized neuronal networks from theta to gamma frequencies to link sensory and attentional functions. DOI: http://dx.doi.org/10.7554/eLife.13451.001 PMID:27669146

  13. Perceptually tuned low-bit-rate video codec for ATM networks

    NASA Astrophysics Data System (ADS)

    Chou, Chun-Hsien

    1996-02-01

    In order to maintain high visual quality in transmitting low bit-rate video signals over asynchronous transfer mode (ATM) networks, a layered coding scheme that incorporates the human visual system (HVS), motion compensation (MC), and conditional replenishment (CR) is presented in this paper. An empirical perceptual model is proposed to estimate the spatio- temporal just-noticeable distortion (STJND) profile for each frame, by which perceptually important (PI) prediction-error signals can be located. Because of the limited channel capacity of the base layer, only coded data of motion vectors, the PI signals within a small strip of the prediction-error image and, if there are remaining bits, the PI signals outside the strip are transmitted by the cells of the base-layer channel. The rest of the coded data are transmitted by the second-layer cells which may be lost due to channel error or network congestion. Simulation results show that visual quality of the reconstructed CIF sequence is acceptable when the capacity of the base-layer channel is allocated with 2 multiplied by 64 kbps and the cells of the second layer are all lost.

  14. Empirical Comparison of Visualization Tools for Larger-Scale Network Analysis

    DOE PAGES

    Pavlopoulos, Georgios A.; Paez-Espino, David; Kyrpides, Nikos C.; ...

    2017-07-18

    Gene expression, signal transduction, protein/chemical interactions, biomedical literature cooccurrences, and other concepts are often captured in biological network representations where nodes represent a certain bioentity and edges the connections between them. While many tools to manipulate, visualize, and interactively explore such networks already exist, only few of them can scale up and follow today’s indisputable information growth. In this review, we shortly list a catalog of available network visualization tools and, from a user-experience point of view, we identify four candidate tools suitable for larger-scale network analysis, visualization, and exploration. Lastly, we comment on their strengths and their weaknesses andmore » empirically discuss their scalability, user friendliness, and postvisualization capabilities.« less

  15. Empirical Comparison of Visualization Tools for Larger-Scale Network Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pavlopoulos, Georgios A.; Paez-Espino, David; Kyrpides, Nikos C.

    Gene expression, signal transduction, protein/chemical interactions, biomedical literature cooccurrences, and other concepts are often captured in biological network representations where nodes represent a certain bioentity and edges the connections between them. While many tools to manipulate, visualize, and interactively explore such networks already exist, only few of them can scale up and follow today’s indisputable information growth. In this review, we shortly list a catalog of available network visualization tools and, from a user-experience point of view, we identify four candidate tools suitable for larger-scale network analysis, visualization, and exploration. Lastly, we comment on their strengths and their weaknesses andmore » empirically discuss their scalability, user friendliness, and postvisualization capabilities.« less

  16. miRNet - dissecting miRNA-target interactions and functional associations through network-based visual analysis

    PubMed Central

    Fan, Yannan; Siklenka, Keith; Arora, Simran K.; Ribeiro, Paula; Kimmins, Sarah; Xia, Jianguo

    2016-01-01

    MicroRNAs (miRNAs) can regulate nearly all biological processes and their dysregulation is implicated in various complex diseases and pathological conditions. Recent years have seen a growing number of functional studies of miRNAs using high-throughput experimental technologies, which have produced a large amount of high-quality data regarding miRNA target genes and their interactions with small molecules, long non-coding RNAs, epigenetic modifiers, disease associations, etc. These rich sets of information have enabled the creation of comprehensive networks linking miRNAs with various biologically important entities to shed light on their collective functions and regulatory mechanisms. Here, we introduce miRNet, an easy-to-use web-based tool that offers statistical, visual and network-based approaches to help researchers understand miRNAs functions and regulatory mechanisms. The key features of miRNet include: (i) a comprehensive knowledge base integrating high-quality miRNA-target interaction data from 11 databases; (ii) support for differential expression analysis of data from microarray, RNA-seq and quantitative PCR; (iii) implementation of a flexible interface for data filtering, refinement and customization during network creation; (iv) a powerful fully featured network visualization system coupled with enrichment analysis. miRNet offers a comprehensive tool suite to enable statistical analysis and functional interpretation of various data generated from current miRNA studies. miRNet is freely available at http://www.mirnet.ca. PMID:27105848

  17. Toward Rigorous Parameterization of Underconstrained Neural Network Models Through Interactive Visualization and Steering of Connectivity Generation

    PubMed Central

    Nowke, Christian; Diaz-Pier, Sandra; Weyers, Benjamin; Hentschel, Bernd; Morrison, Abigail; Kuhlen, Torsten W.; Peyser, Alexander

    2018-01-01

    Simulation models in many scientific fields can have non-unique solutions or unique solutions which can be difficult to find. Moreover, in evolving systems, unique final state solutions can be reached by multiple different trajectories. Neuroscience is no exception. Often, neural network models are subject to parameter fitting to obtain desirable output comparable to experimental data. Parameter fitting without sufficient constraints and a systematic exploration of the possible solution space can lead to conclusions valid only around local minima or around non-minima. To address this issue, we have developed an interactive tool for visualizing and steering parameters in neural network simulation models. In this work, we focus particularly on connectivity generation, since finding suitable connectivity configurations for neural network models constitutes a complex parameter search scenario. The development of the tool has been guided by several use cases—the tool allows researchers to steer the parameters of the connectivity generation during the simulation, thus quickly growing networks composed of multiple populations with a targeted mean activity. The flexibility of the software allows scientists to explore other connectivity and neuron variables apart from the ones presented as use cases. With this tool, we enable an interactive exploration of parameter spaces and a better understanding of neural network models and grapple with the crucial problem of non-unique network solutions and trajectories. In addition, we observe a reduction in turn around times for the assessment of these models, due to interactive visualization while the simulation is computed. PMID:29937723

  18. Compressing Test and Evaluation by Using Flow Data for Scalable Network Traffic Analysis

    DTIC Science & Technology

    2014-10-01

    test events, quality of service and other key metrics of military systems and networks are evaluated. Network data captured in standard flow formats...mentioned here. The Ozone Widget Framework (Next Century, n.d.) has proven to be very useful. Also, an extensive, clean, and optimized JavaScript ...library for visualizing many types of data can be found in D3–Data Driven Documents (Bostock, 2013). Quality of Service from Flow Two essential metrics of

  19. Design of UAV-Embedded Microphone Array System for Sound Source Localization in Outdoor Environments †

    PubMed Central

    Hoshiba, Kotaro; Washizaki, Kai; Wakabayashi, Mizuho; Ishiki, Takahiro; Bando, Yoshiaki; Gabriel, Daniel; Nakadai, Kazuhiro; Okuno, Hiroshi G.

    2017-01-01

    In search and rescue activities, unmanned aerial vehicles (UAV) should exploit sound information to compensate for poor visual information. This paper describes the design and implementation of a UAV-embedded microphone array system for sound source localization in outdoor environments. Four critical development problems included water-resistance of the microphone array, efficiency in assembling, reliability of wireless communication, and sufficiency of visualization tools for operators. To solve these problems, we developed a spherical microphone array system (SMAS) consisting of a microphone array, a stable wireless network communication system, and intuitive visualization tools. The performance of SMAS was evaluated with simulated data and a demonstration in the field. Results confirmed that the SMAS provides highly accurate localization, water resistance, prompt assembly, stable wireless communication, and intuitive information for observers and operators. PMID:29099790

  20. Design of UAV-Embedded Microphone Array System for Sound Source Localization in Outdoor Environments.

    PubMed

    Hoshiba, Kotaro; Washizaki, Kai; Wakabayashi, Mizuho; Ishiki, Takahiro; Kumon, Makoto; Bando, Yoshiaki; Gabriel, Daniel; Nakadai, Kazuhiro; Okuno, Hiroshi G

    2017-11-03

    In search and rescue activities, unmanned aerial vehicles (UAV) should exploit sound information to compensate for poor visual information. This paper describes the design and implementation of a UAV-embedded microphone array system for sound source localization in outdoor environments. Four critical development problems included water-resistance of the microphone array, efficiency in assembling, reliability of wireless communication, and sufficiency of visualization tools for operators. To solve these problems, we developed a spherical microphone array system (SMAS) consisting of a microphone array, a stable wireless network communication system, and intuitive visualization tools. The performance of SMAS was evaluated with simulated data and a demonstration in the field. Results confirmed that the SMAS provides highly accurate localization, water resistance, prompt assembly, stable wireless communication, and intuitive information for observers and operators.

  1. VRML and Collaborative Environments: New Tools for Networked Visualization

    NASA Astrophysics Data System (ADS)

    Crutcher, R. M.; Plante, R. L.; Rajlich, P.

    We present two new applications that engage the network as a tool for astronomical research and/or education. The first is a VRML server which allows users over the Web to interactively create three-dimensional visualizations of FITS images contained in the NCSA Astronomy Digital Image Library (ADIL). The server's Web interface allows users to select images from the ADIL, fill in processing parameters, and create renderings featuring isosurfaces, slices, contours, and annotations; the often extensive computations are carried out on an NCSA SGI supercomputer server without the user having an individual account on the system. The user can then download the 3D visualizations as VRML files, which may be rotated and manipulated locally on virtually any class of computer. The second application is the ADILBrowser, a part of the NCSA Horizon Image Data Browser Java package. ADILBrowser allows a group of participants to browse images from the ADIL within a collaborative session. The collaborative environment is provided by the NCSA Habanero package which includes text and audio chat tools and a white board. The ADILBrowser is just an example of a collaborative tool that can be built with the Horizon and Habanero packages. The classes provided by these packages can be assembled to create custom collaborative applications that visualize data either from local disk or from anywhere on the network.

  2. Visual cortical areas of the mouse: comparison of parcellation and network structure with primates

    PubMed Central

    Laramée, Marie-Eve; Boire, Denis

    2015-01-01

    Brains have evolved to optimize sensory processing. In primates, complex cognitive tasks must be executed and evolution led to the development of large brains with many cortical areas. Rodents do not accomplish cognitive tasks of the same level of complexity as primates and remain with small brains both in relative and absolute terms. But is a small brain necessarily a simple brain? In this review, several aspects of the visual cortical networks have been compared between rodents and primates. The visual system has been used as a model to evaluate the level of complexity of the cortical circuits at the anatomical and functional levels. The evolutionary constraints are first presented in order to appreciate the rules for the development of the brain and its underlying circuits. The organization of sensory pathways, with their parallel and cross-modal circuits, is also examined. Other features of brain networks, often considered as imposing constraints on the development of underlying circuitry, are also discussed and their effect on the complexity of the mouse and primate brain are inspected. In this review, we discuss the common features of cortical circuits in mice and primates and see how these can be useful in understanding visual processing in these animals. PMID:25620914

  3. Visual cortical areas of the mouse: comparison of parcellation and network structure with primates.

    PubMed

    Laramée, Marie-Eve; Boire, Denis

    2014-01-01

    Brains have evolved to optimize sensory processing. In primates, complex cognitive tasks must be executed and evolution led to the development of large brains with many cortical areas. Rodents do not accomplish cognitive tasks of the same level of complexity as primates and remain with small brains both in relative and absolute terms. But is a small brain necessarily a simple brain? In this review, several aspects of the visual cortical networks have been compared between rodents and primates. The visual system has been used as a model to evaluate the level of complexity of the cortical circuits at the anatomical and functional levels. The evolutionary constraints are first presented in order to appreciate the rules for the development of the brain and its underlying circuits. The organization of sensory pathways, with their parallel and cross-modal circuits, is also examined. Other features of brain networks, often considered as imposing constraints on the development of underlying circuitry, are also discussed and their effect on the complexity of the mouse and primate brain are inspected. In this review, we discuss the common features of cortical circuits in mice and primates and see how these can be useful in understanding visual processing in these animals.

  4. A Space and Atmospheric Visualization Science System

    NASA Technical Reports Server (NTRS)

    Szuszczewicz, E. P.; Blanchard, P.; Mankofsky, A.; Goodrich, C.; Kamins, D.; Kulkarni, R.; Mcnabb, D.; Moroh, M.

    1994-01-01

    SAVS (a Space and Atmospheric Visualization Science system) is an integrated system with user-friendly functionality that employs a 'push-button' software environment that mimics the logical scientific processes in data acquisition, reduction, analysis, and visualization. All of this is accomplished without requiring a detailed understanding of the methods, networks, and modules that link the tools and effectively execute the functions. This report describes SAVS and its components, followed by several applications based on generic research interests in interplanetary and magnetospheric physics (IMP/ISTP), active experiments in space (CRRES), and mission planning focused on the earth's thermospheric, ionospheric, and mesospheric domains (TIMED). The final chapters provide a user-oriented description of interface functionalities, hands-on operations, and customized modules, with details of the primary modules presented in the appendices. The overall intent of the report is to reflect the accomplishments of the three-year development effort and to introduce potential users to the power and utility of the integrated data acquisition, analysis, and visualization system.

  5. Vascular Cell Induction Culture System Using Arabidopsis Leaves (VISUAL) Reveals the Sequential Differentiation of Sieve Element-Like Cells.

    PubMed

    Kondo, Yuki; Nurani, Alif Meem; Saito, Chieko; Ichihashi, Yasunori; Saito, Masato; Yamazaki, Kyoko; Mitsuda, Nobutaka; Ohme-Takagi, Masaru; Fukuda, Hiroo

    2016-06-01

    Cell differentiation is a complex process involving multiple steps, from initial cell fate specification to final differentiation. Procambial/cambial cells, which act as vascular stem cells, differentiate into both xylem and phloem cells during vascular development. Recent studies have identified regulatory cascades for xylem differentiation. However, the molecular mechanism underlying phloem differentiation is largely unexplored due to technical challenges. Here, we established an ectopic induction system for phloem differentiation named Vascular Cell Induction Culture System Using Arabidopsis Leaves (VISUAL). Our results verified similarities between VISUAL-induced Arabidopsis thaliana phloem cells and in vivo sieve elements. We performed network analysis using transcriptome data with VISUAL to dissect the processes underlying phloem differentiation, eventually identifying a factor involved in the regulation of the master transcription factor gene APL Thus, our culture system opens up new avenues not only for genetic studies of phloem differentiation, but also for future investigations of multidirectional differentiation from vascular stem cells. © 2016 American Society of Plant Biologists. All rights reserved.

  6. Toward the establishment of design guidelines for effective 3D perspective interfaces

    NASA Astrophysics Data System (ADS)

    Fitzhugh, Elisabeth; Dixon, Sharon; Aleva, Denise; Smith, Eric; Ghrayeb, Joseph; Douglas, Lisa

    2009-05-01

    The propagation of information operation technologies, with correspondingly vast amounts of complex network information to be conveyed, significantly impacts operator workload. Information management research is rife with efforts to develop schemes to aid operators to identify, review, organize, and retrieve the wealth of available data. Data may take on such distinct forms as intelligence libraries, logistics databases, operational environment models, or network topologies. Increased use of taxonomies and semantic technologies opens opportunities to employ network visualization as a display mechanism for diverse information aggregations. The broad applicability of network visualizations is still being tested, but in current usage, the complexity of densely populated abstract networks suggests the potential utility of 3D. Employment of 2.5D in network visualization, using classic perceptual cues, creates a 3D experience within a 2D medium. It is anticipated that use of 3D perspective (2.5D) will enhance user ability to visually inspect large, complex, multidimensional networks. Current research for 2.5D visualizations demonstrates that display attributes, including color, shape, size, lighting, atmospheric effects, and shadows, significantly impact operator experience. However, guidelines for utilization of attributes in display design are limited. This paper discusses pilot experimentation intended to identify potential problem areas arising from these cues and determine how best to optimize perceptual cue settings. Development of optimized design guidelines will ensure that future experiments, comparing network displays with other visualizations, are not confounded or impeded by suboptimal attribute characterization. Current experimentation is anticipated to support development of cost-effective, visually effective methods to implement 3D in military applications.

  7. Congenital blindness is associated with large-scale reorganization of anatomical networks.

    PubMed

    Hasson, Uri; Andric, Michael; Atilgan, Hicret; Collignon, Olivier

    2016-03-01

    Blindness is a unique model for understanding the role of experience in the development of the brain's functional and anatomical architecture. Documenting changes in the structure of anatomical networks for this population would substantiate the notion that the brain's core network-level organization may undergo neuroplasticity as a result of life-long experience. To examine this issue, we compared whole-brain networks of regional cortical-thickness covariance in early blind and matched sighted individuals. This covariance is thought to reflect signatures of integration between systems involved in similar perceptual/cognitive functions. Using graph-theoretic metrics, we identified a unique mode of anatomical reorganization in the blind that differed from that found for sighted. This was seen in that network partition structures derived from subgroups of blind were more similar to each other than they were to partitions derived from sighted. Notably, after deriving network partitions, we found that language and visual regions tended to reside within separate modules in sighted but showed a pattern of merging into shared modules in the blind. Our study demonstrates that early visual deprivation triggers a systematic large-scale reorganization of whole-brain cortical-thickness networks, suggesting changes in how occipital regions interface with other functional networks in the congenitally blind. Copyright © 2015 The Authors. Published by Elsevier Inc. All rights reserved.

  8. CI-KNOW: Cyberinfrastructure Knowledge Networks on the Web. A Social Network Enabled Recommender System for Locating Resources in Cyberinfrastructures

    NASA Astrophysics Data System (ADS)

    Green, H. D.; Contractor, N. S.; Yao, Y.

    2006-12-01

    A knowledge network is a multi-dimensional network created from the interactions and interconnections among the scientists, documents, data, analytic tools, and interactive collaboration spaces (like forums and wikis) associated with a collaborative environment. CI-KNOW is a suite of software tools that leverages automated data collection, social network theories, analysis techniques and algorithms to infer an individual's interests and expertise based on their interactions and activities within a knowledge network. The CI-KNOW recommender system mines the knowledge network associated with a scientific community's use of cyberinfrastructure tools and uses relational metadata to record connections among entities in the knowledge network. Recent developments in social network theories and methods provide the backbone for a modular system that creates recommendations from relational metadata. A network navigation portlet allows users to locate colleagues, documents, data or analytic tools in the knowledge network and to explore their networks through a visual, step-wise process. An internal auditing portlet offers administrators diagnostics to assess the growth and health of the entire knowledge network. The first instantiation of the prototype CI-KNOW system is part of the Environmental Cyberinfrastructure Demonstration project at the National Center for Supercomputing Applications, which supports the activities of hydrologic and environmental science communities (CLEANER and CUAHSI) under the umbrella of the WATERS network environmental observatory planning activities (http://cleaner.ncsa.uiuc.edu). This poster summarizes the key aspects of the CI-KNOW system, highlighting the key inputs, calculation mechanisms, and output modalities.

  9. Lifting Scheme DWT Implementation in a Wireless Vision Sensor Network

    NASA Astrophysics Data System (ADS)

    Ong, Jia Jan; Ang, L.-M.; Seng, K. P.

    This paper presents the practical implementation of a Wireless Visual Sensor Network (WVSN) with DWT processing on the visual nodes. WVSN consists of visual nodes that capture video and transmit to the base-station without processing. Limitation of network bandwidth restrains the implementation of real time video streaming from remote visual nodes through wireless communication. Three layers of DWT filters are implemented to process the captured image from the camera. With having all the wavelet coefficients produced, it is possible just to transmit the low frequency band coefficients and obtain an approximate image at the base-station. This will reduce the amount of power required in transmission. When necessary, transmitting all the wavelet coefficients will produce the full detail of image, which is similar to the image captured at the visual nodes. The visual node combines the CMOS camera, Xilinx Spartan-3L FPGA and wireless ZigBee® network that uses the Ember EM250 chip.

  10. Digital implementation of a neural network for imaging

    NASA Astrophysics Data System (ADS)

    Wood, Richard; McGlashan, Alex; Yatulis, Jay; Mascher, Peter; Bruce, Ian

    2012-10-01

    This paper outlines the design and testing of a digital imaging system that utilizes an artificial neural network with unsupervised and supervised learning to convert streaming input (real time) image space into parameter space. The primary objective of this work is to investigate the effectiveness of using a neural network to significantly reduce the information density of streaming images so that objects can be readily identified by a limited set of primary parameters and act as an enhanced human machine interface (HMI). Many applications are envisioned including use in biomedical imaging, anomaly detection and as an assistive device for the visually impaired. A digital circuit was designed and tested using a Field Programmable Gate Array (FPGA) and an off the shelf digital camera. Our results indicate that the networks can be readily trained when subject to limited sets of objects such as the alphabet. We can also separate limited object sets with rotational and positional invariance. The results also show that limited visual fields form with only local connectivity.

  11. Music and words in the visual cortex: The impact of musical expertise.

    PubMed

    Mongelli, Valeria; Dehaene, Stanislas; Vinckier, Fabien; Peretz, Isabelle; Bartolomeo, Paolo; Cohen, Laurent

    2017-01-01

    How does the human visual system accommodate expertise for two simultaneously acquired symbolic systems? We used fMRI to compare activations induced in the visual cortex by musical notation, written words and other classes of objects, in professional musicians and in musically naïve controls. First, irrespective of expertise, selective activations for music were posterior and lateral to activations for words in the left occipitotemporal cortex. This indicates that symbols characterized by different visual features engage distinct cortical areas. Second, musical expertise increased the volume of activations for music and led to an anterolateral displacement of word-related activations. In musicians, there was also a dramatic increase of the brain-scale networks connected to the music-selective visual areas. Those findings reveal that acquiring a double visual expertise involves an expansion of category-selective areas, the development of novel long-distance functional connectivity, and possibly some competition between categories for the colonization of cortical space. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Development of the updated system of city underground pipelines based on Visual Studio

    NASA Astrophysics Data System (ADS)

    Zhang, Jianxiong; Zhu, Yun; Li, Xiangdong

    2009-10-01

    Our city has owned the integrated pipeline network management system with ArcGIS Engine 9.1 as the bottom development platform and with Oracle9i as basic database for storaging data. In this system, ArcGIS SDE9.1 is applied as the spatial data engine, and the system was a synthetic management software developed with Visual Studio visualization procedures development tools. As the pipeline update function of the system has the phenomenon of slower update and even sometimes the data lost, to ensure the underground pipeline data can real-time be updated conveniently and frequently, and the actuality and integrity of the underground pipeline data, we have increased a new update module in the system developed and researched by ourselves. The module has the powerful data update function, and can realize the function of inputting and outputting and rapid update volume of data. The new developed module adopts Visual Studio visualization procedures development tools, and uses access as the basic database to storage data. We can edit the graphics in AutoCAD software, and realize the database update using link between the graphics and the system. Practice shows that the update module has good compatibility with the original system, reliable and high update efficient of the database.

  13. CityWaterBalance: Track Flows of Water Through an Urban System

    EPA Science Inventory

    CityWaterBalance provides a reproducible workflow for studying an urban water system. The network of urban water flows and storages can be modeled and visualized. Any city may be modeled with preassembled data, but data for US cities can be gathered via web services using this p...

  14. Visual Based Retrieval Systems and Web Mining--Introduction.

    ERIC Educational Resources Information Center

    Iyengar, S. S.

    2001-01-01

    Briefly discusses Web mining and image retrieval techniques, and then presents a summary of articles in this special issue. Articles focus on Web content mining, artificial neural networks as tools for image retrieval, content-based image retrieval systems, and personalizing the Web browsing experience using media agents. (AEF)

  15. Computational and fMRI Studies of Visualization

    DTIC Science & Technology

    2009-03-31

    spatial thinking in high level cognition, such as in problem-solving and reasoning. In conjunction with the experimental work, the project developed a...computational modeling system (4CAPS) as well as the development of 4CAPS models for particular tasks. The cognitive level of 4CAPS accounts for...neuroarchitecture to interpret and predict the brain activation in a network of cortical areas that underpin the performance of a visual thinking task. The

  16. Behavior and neural basis of near-optimal visual search

    PubMed Central

    Ma, Wei Ji; Navalpakkam, Vidhya; Beck, Jeffrey M; van den Berg, Ronald; Pouget, Alexandre

    2013-01-01

    The ability to search efficiently for a target in a cluttered environment is one of the most remarkable functions of the nervous system. This task is difficult under natural circumstances, as the reliability of sensory information can vary greatly across space and time and is typically a priori unknown to the observer. In contrast, visual-search experiments commonly use stimuli of equal and known reliability. In a target detection task, we randomly assigned high or low reliability to each item on a trial-by-trial basis. An optimal observer would weight the observations by their trial-to-trial reliability and combine them using a specific nonlinear integration rule. We found that humans were near-optimal, regardless of whether distractors were homogeneous or heterogeneous and whether reliability was manipulated through contrast or shape. We present a neural-network implementation of near-optimal visual search based on probabilistic population coding. The network matched human performance. PMID:21552276

  17. Visualization of suspicious lesions in breast MRI based on intelligent neural systems

    NASA Astrophysics Data System (ADS)

    Twellmann, Thorsten; Lange, Oliver; Nattkemper, Tim Wilhelm; Meyer-Bäse, Anke

    2006-05-01

    Intelligent medical systems based on supervised and unsupervised artificial neural networks are applied to the automatic visualization and classification of suspicious lesions in breast MRI. These systems represent an important component of future sophisticated computer-aided diagnosis systems and enable the extraction of spatial and temporal features of dynamic MRI data stemming from patients with confirmed lesion diagnosis. By taking into account the heterogenity of the cancerous tissue, these techniques reveal the malignant, benign and normal kinetic signals and and provide a regional subclassification of pathological breast tissue. Intelligent medical systems are expected to have substantial implications in healthcare politics by contributing to the diagnosis of indeterminate breast lesions by non-invasive imaging.

  18. A Global System for Transportation Simulation and Visualization in Emergency Evacuation Scenarios

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lu, Wei; Liu, Cheng; Thomas, Neil

    2015-01-01

    Simulation-based studies are frequently used for evacuation planning and decision making processes. Given the transportation systems complexity and data availability, most evacuation simulation models focus on certain geographic areas. With routine improvement of OpenStreetMap road networks and LandScanTM global population distribution data, we present WWEE, a uniform system for world-wide emergency evacuation simulations. WWEE uses unified data structure for simulation inputs. It also integrates a super-node trip distribution model as the default simulation parameter to improve the system computational performance. Two levels of visualization tools are implemented for evacuation performance analysis, including link-based macroscopic visualization and vehicle-based microscopic visualization. Formore » left-hand and right-hand traffic patterns in different countries, the authors propose a mirror technique to experiment with both scenarios without significantly changing traffic simulation models. Ten cities in US, Europe, Middle East, and Asia are modeled for demonstration. With default traffic simulation models for fast and easy-to-use evacuation estimation and visualization, WWEE also retains the capability of interactive operation for users to adopt customized traffic simulation models. For the first time, WWEE provides a unified platform for global evacuation researchers to estimate and visualize their strategies performance of transportation systems under evacuation scenarios.« less

  19. Visual social network analysis: effective approach to model complex human social, behaviour & culture.

    PubMed

    Ahram, Tareq Z; Karwowski, Waldemar

    2012-01-01

    The advent and adoption of internet-based social networking has significantly altered our daily lives. The educational community has taken notice of the positive aspects of social networking such as creation of blogs and to support groups of system designers going through the same challenges and difficulties. This paper introduces a social networking framework for collaborative education, design and modeling of the next generation of smarter products and services. Human behaviour modeling in social networking application aims to ensure that human considerations for learners and designers have a prominent place in the integrated design and development of sustainable, smarter products throughout the total system lifecycle. Social networks blend self-directed learning and prescribed, existing information. The self-directed element creates interest within a learner and the ability to access existing information facilitates its transfer, and eventual retention of knowledge acquired.

  20. Content-specific network analysis of peer-to-peer communication in an online community for smoking cessation.

    PubMed

    Myneni, Sahiti; Cobb, Nathan K; Cohen, Trevor

    2016-01-01

    Analysis of user interactions in online communities could improve our understanding of health-related behaviors and inform the design of technological solutions that support behavior change. However, to achieve this we would need methods that provide granular perspective, yet are scalable. In this paper, we present a methodology for high-throughput semantic and network analysis of large social media datasets, combining semi-automated text categorization with social network analytics. We apply this method to derive content-specific network visualizations of 16,492 user interactions in an online community for smoking cessation. Performance of the categorization system was reasonable (average F-measure of 0.74, with system-rater reliability approaching rater-rater reliability). The resulting semantically specific network analysis of user interactions reveals content- and behavior-specific network topologies. Implications for socio-behavioral health and wellness platforms are also discussed.

  1. Detecting Disease Specific Pathway Substructures through an Integrated Systems Biology Approach

    PubMed Central

    Alaimo, Salvatore; Marceca, Gioacchino Paolo; Ferro, Alfredo; Pulvirenti, Alfredo

    2017-01-01

    In the era of network medicine, pathway analysis methods play a central role in the prediction of phenotype from high throughput experiments. In this paper, we present a network-based systems biology approach capable of extracting disease-perturbed subpathways within pathway networks in connection with expression data taken from The Cancer Genome Atlas (TCGA). Our system extends pathways with missing regulatory elements, such as microRNAs, and their interactions with genes. The framework enables the extraction, visualization, and analysis of statistically significant disease-specific subpathways through an easy to use web interface. Our analysis shows that the methodology is able to fill the gap in current techniques, allowing a more comprehensive analysis of the phenomena underlying disease states. PMID:29657291

  2. A new SMART sensing system for aerospace structures

    NASA Astrophysics Data System (ADS)

    Zhang, David C.; Yu, Pin; Beard, Shawn; Qing, Peter; Kumar, Amrita; Chang, Fu-Kuo

    2007-04-01

    It is essential to ensure the safety and reliability of in-service structures such as unmanned vehicles by detecting structural cracking, corrosion, delamination, material degradation and other types of damage in time. Utilization of an integrated sensor network system can enable automatic inspection of such damages ultimately. Using a built-in network of actuators and sensors, Acellent is providing tools for advanced structural diagnostics. Acellent's integrated structural health monitoring system consists of an actuator/sensor network, supporting signal generation and data acquisition hardware, and data processing, visualization and analysis software. This paper describes the various features of Acellent's latest SMART sensing system. The new system is USB-based and is ultra-portable using the state-of-the-art technology, while delivering many functions such as system self-diagnosis, sensor diagnosis, through-transmission mode and pulse-echo mode of operation and temperature measurement. Performance of the new system was evaluated for assessment of damage in composite structures.

  3. Utilizing Semantic Big Data for realizing a National-scale Infrastructure Vulnerability Analysis System

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chinthavali, Supriya; Shankar, Mallikarjun

    Critical Infrastructure systems(CIs) such as energy, water, transportation and communication are highly interconnected and mutually dependent in complex ways. Robust modeling of CIs interconnections is crucial to identify vulnerabilities in the CIs. We present here a national-scale Infrastructure Vulnerability Analysis System (IVAS) vision leveraging Se- mantic Big Data (SBD) tools, Big Data, and Geographical Information Systems (GIS) tools. We survey existing ap- proaches on vulnerability analysis of critical infrastructures and discuss relevant systems and tools aligned with our vi- sion. Next, we present a generic system architecture and discuss challenges including: (1) Constructing and manag- ing a CI network-of-networks graph,more » (2) Performing analytic operations at scale, and (3) Interactive visualization of ana- lytic output to generate meaningful insights. We argue that this architecture acts as a baseline to realize a national-scale network based vulnerability analysis system.« less

  4. A BHR Composite Network-Based Visualization Method for Deformation Risk Level of Underground Space

    PubMed Central

    Zheng, Wei; Zhang, Xiaoya; Lu, Qi

    2015-01-01

    This study proposes a visualization processing method for the deformation risk level of underground space. The proposed method is based on a BP-Hopfield-RGB (BHR) composite network. Complex environmental factors are integrated in the BP neural network. Dynamic monitoring data are then automatically classified in the Hopfield network. The deformation risk level is combined with the RGB color space model and is displayed visually in real time, after which experiments are conducted with the use of an ultrasonic omnidirectional sensor device for structural deformation monitoring. The proposed method is also compared with some typical methods using a benchmark dataset. Results show that the BHR composite network visualizes the deformation monitoring process in real time and can dynamically indicate dangerous zones. PMID:26011618

  5. A grid layout algorithm for automatic drawing of biochemical networks.

    PubMed

    Li, Weijiang; Kurata, Hiroyuki

    2005-05-01

    Visualization is indispensable in the research of complex biochemical networks. Available graph layout algorithms are not adequate for satisfactorily drawing such networks. New methods are required to visualize automatically the topological architectures and facilitate the understanding of the functions of the networks. We propose a novel layout algorithm to draw complex biochemical networks. A network is modeled as a system of interacting nodes on squared grids. A discrete cost function between each node pair is designed based on the topological relation and the geometric positions of the two nodes. The layouts are produced by minimizing the total cost. We design a fast algorithm to minimize the discrete cost function, by which candidate layouts can be produced efficiently. A simulated annealing procedure is used to choose better candidates. Our algorithm demonstrates its ability to exhibit cluster structures clearly in relatively compact layout areas without any prior knowledge. We developed Windows software to implement the algorithm for CADLIVE. All materials can be freely downloaded from http://kurata21.bio.kyutech.ac.jp/grid/grid_layout.htm; http://www.cadlive.jp/ http://kurata21.bio.kyutech.ac.jp/grid/grid_layout.htm; http://www.cadlive.jp/

  6. Biologically inspired computation and learning in Sensorimotor Systems

    NASA Astrophysics Data System (ADS)

    Lee, Daniel D.; Seung, H. S.

    2001-11-01

    Networking systems presently lack the ability to intelligently process the rich multimedia content of the data traffic they carry. Endowing artificial systems with the ability to adapt to changing conditions requires algorithms that can rapidly learn from examples. We demonstrate the application of such learning algorithms on an inexpensive quadruped robot constructed to perform simple sensorimotor tasks. The robot learns to track a particular object by discovering the salient visual and auditory cues unique to that object. The system uses a convolutional neural network that automatically combines color, luminance, motion, and auditory information. The weights of the networks are adjusted using feedback from a teacher to reflect the reliability of the various input channels in the surrounding environment. Additionally, the robot is able to compensate for its own motion by adapting the parameters of a vestibular ocular reflex system.

  7. Visual imagery and functional connectivity in blindness: a single-case study

    PubMed Central

    Boucard, Christine C.; Rauschecker, Josef P.; Neufang, Susanne; Berthele, Achim; Doll, Anselm; Manoliu, Andrej; Riedl, Valentin; Sorg, Christian; Wohlschläger, Afra; Mühlau, Mark

    2016-01-01

    We present a case report on visual brain plasticity after total blindness acquired in adulthood. SH lost her sight when she was 27. Despite having been totally blind for 43 years, she reported to strongly rely on her vivid visual imagery. Three-Tesla magnetic resonance imaging (MRI) of SH and age-matched controls was performed. The MRI sequence included anatomical MRI, resting-state functional MRI, and task-related functional MRI where SH was instructed to imagine colours, faces, and motion. Compared to controls, voxel-based analysis revealed white matter loss along SH's visual pathway as well as grey matter atrophy in the calcarine sulci. Yet we demonstrated activation in visual areas, including V1, using functional MRI. Of the four identified visual resting-state networks, none showed alterations in spatial extent; hence, SH's preserved visual imagery seems to be mediated by intrinsic brain networks of normal extent. Time courses of two of these networks showed increased correlation with that of the inferior posterior default mode network, which may reflect adaptive changes supporting SH's strong internal visual representations. Overall, our findings demonstrate that conscious visual experience is possible even after years of absence of extrinsic input. PMID:25690326

  8. Visual imagery and functional connectivity in blindness: a single-case study.

    PubMed

    Boucard, Christine C; Rauschecker, Josef P; Neufang, Susanne; Berthele, Achim; Doll, Anselm; Manoliu, Andrej; Riedl, Valentin; Sorg, Christian; Wohlschläger, Afra; Mühlau, Mark

    2016-05-01

    We present a case report on visual brain plasticity after total blindness acquired in adulthood. SH lost her sight when she was 27. Despite having been totally blind for 43 years, she reported to strongly rely on her vivid visual imagery. Three-Tesla magnetic resonance imaging (MRI) of SH and age-matched controls was performed. The MRI sequence included anatomical MRI, resting-state functional MRI, and task-related functional MRI where SH was instructed to imagine colours, faces, and motion. Compared to controls, voxel-based analysis revealed white matter loss along SH's visual pathway as well as grey matter atrophy in the calcarine sulci. Yet we demonstrated activation in visual areas, including V1, using functional MRI. Of the four identified visual resting-state networks, none showed alterations in spatial extent; hence, SH's preserved visual imagery seems to be mediated by intrinsic brain networks of normal extent. Time courses of two of these networks showed increased correlation with that of the inferior posterior default mode network, which may reflect adaptive changes supporting SH's strong internal visual representations. Overall, our findings demonstrate that conscious visual experience is possible even after years of absence of extrinsic input.

  9. An Attractive Reelin Gradient Establishes Synaptic Lamination in the Vertebrate Visual System.

    PubMed

    Di Donato, Vincenzo; De Santis, Flavia; Albadri, Shahad; Auer, Thomas Oliver; Duroure, Karine; Charpentier, Marine; Concordet, Jean-Paul; Gebhardt, Christoph; Del Bene, Filippo

    2018-03-07

    A conserved organizational and functional principle of neural networks is the segregation of axon-dendritic synaptic connections into laminae. Here we report that targeting of synaptic laminae by retinal ganglion cell (RGC) arbors in the vertebrate visual system is regulated by a signaling system relying on target-derived Reelin and VLDLR/Dab1a on the projecting neurons. Furthermore, we find that Reelin is distributed as a gradient on the target tissue and stabilized by heparan sulfate proteoglycans (HSPGs) in the extracellular matrix (ECM). Through genetic manipulations, we show that this Reelin gradient is important for laminar targeting and that it is attractive for RGC axons. Finally, we suggest a comprehensive model of synaptic lamina formation in which attractive Reelin counter-balances repulsive Slit1, thereby guiding RGC axons toward single synaptic laminae. We establish a mechanism that may represent a general principle for neural network assembly in vertebrate species and across different brain areas. Copyright © 2018 Elsevier Inc. All rights reserved.

  10. Joint Attention and Brain Functional Connectivity in Infants and Toddlers.

    PubMed

    Eggebrecht, Adam T; Elison, Jed T; Feczko, Eric; Todorov, Alexandre; Wolff, Jason J; Kandala, Sridhar; Adams, Chloe M; Snyder, Abraham Z; Lewis, John D; Estes, Annette M; Zwaigenbaum, Lonnie; Botteron, Kelly N; McKinstry, Robert C; Constantino, John N; Evans, Alan; Hazlett, Heather C; Dager, Stephen; Paterson, Sarah J; Schultz, Robert T; Styner, Martin A; Gerig, Guido; Das, Samir; Kostopoulos, Penelope; Schlaggar, Bradley L; Petersen, Steven E; Piven, Joseph; Pruett, John R

    2017-03-01

    Initiating joint attention (IJA), the behavioral instigation of coordinated focus of 2 people on an object, emerges over the first 2 years of life and supports social-communicative functioning related to the healthy development of aspects of language, empathy, and theory of mind. Deficits in IJA provide strong early indicators for autism spectrum disorder, and therapies targeting joint attention have shown tremendous promise. However, the brain systems underlying IJA in early childhood are poorly understood, due in part to significant methodological challenges in imaging localized brain function that supports social behaviors during the first 2 years of life. Herein, we show that the functional organization of the brain is intimately related to the emergence of IJA using functional connectivity magnetic resonance imaging and dimensional behavioral assessments in a large semilongitudinal cohort of infants and toddlers. In particular, though functional connections spanning the brain are involved in IJA, the strongest brain-behavior associations cluster within connections between a small subset of functional brain networks; namely between the visual network and dorsal attention network and between the visual network and posterior cingulate aspects of the default mode network. These observations mark the earliest known description of how functional brain systems underlie a burgeoning fundamental social behavior, may help improve the design of targeted therapies for neurodevelopmental disorders, and, more generally, elucidate physiological mechanisms essential to healthy social behavior development. © The Author 2017. Published by Oxford University Press.

  11. Joint Attention and Brain Functional Connectivity in Infants and Toddlers

    PubMed Central

    Eggebrecht, Adam T.; Elison, Jed T.; Feczko, Eric; Todorov, Alexandre; Wolff, Jason J.; Kandala, Sridhar; Adams, Chloe M.; Snyder, Abraham Z.; Lewis, John D.; Estes, Annette M.; Zwaigenbaum, Lonnie; Botteron, Kelly N.; McKinstry, Robert C.; Constantino, John N.; Evans, Alan; Hazlett, Heather C.; Dager, Stephen; Paterson, Sarah J.; Schultz, Robert T.; Styner, Martin A.; Gerig, Guido; Das, Samir; Kostopoulos, Penelope; Schlaggar, Bradley L.; Petersen, Steven E.; Piven, Joseph; Pruett, John R.

    2017-01-01

    Abstract Initiating joint attention (IJA), the behavioral instigation of coordinated focus of 2 people on an object, emerges over the first 2 years of life and supports social-communicative functioning related to the healthy development of aspects of language, empathy, and theory of mind. Deficits in IJA provide strong early indicators for autism spectrum disorder, and therapies targeting joint attention have shown tremendous promise. However, the brain systems underlying IJA in early childhood are poorly understood, due in part to significant methodological challenges in imaging localized brain function that supports social behaviors during the first 2 years of life. Herein, we show that the functional organization of the brain is intimately related to the emergence of IJA using functional connectivity magnetic resonance imaging and dimensional behavioral assessments in a large semilongitudinal cohort of infants and toddlers. In particular, though functional connections spanning the brain are involved in IJA, the strongest brain-behavior associations cluster within connections between a small subset of functional brain networks; namely between the visual network and dorsal attention network and between the visual network and posterior cingulate aspects of the default mode network. These observations mark the earliest known description of how functional brain systems underlie a burgeoning fundamental social behavior, may help improve the design of targeted therapies for neurodevelopmental disorders, and, more generally, elucidate physiological mechanisms essential to healthy social behavior development. PMID:28062515

  12. Representation of visual symbols in the visual word processing network.

    PubMed

    Muayqil, Taim; Davies-Thompson, Jodie; Barton, Jason J S

    2015-03-01

    Previous studies have shown that word processing involves a predominantly left-sided occipitotemporal network. Words are a form of symbolic representation, in that they are arbitrary perceptual stimuli that represent other objects, actions or concepts. Lesions of parts of the visual word processing network can cause alexia, which can be associated with difficulty processing other types of symbols such as musical notation or road signs. We investigated whether components of the visual word processing network were also activated by other types of symbols. In 16 music-literate subjects, we defined the visual word network using fMRI and examined responses to four symbolic categories: visual words, musical notation, instructive symbols (e.g. traffic signs), and flags and logos. For each category we compared responses not only to scrambled stimuli, but also to similar stimuli that lacked symbolic meaning. The left visual word form area and a homologous right fusiform region responded similarly to all four categories, but equally to both symbolic and non-symbolic equivalents. Greater response to symbolic than non-symbolic stimuli occurred only in the left inferior frontal and middle temporal gyri, but only for words, and in the case of the left inferior frontal gyri, also for musical notation. A whole-brain analysis comparing symbolic versus non-symbolic stimuli revealed a distributed network of inferior temporooccipital and parietal regions that differed for different symbols. The fusiform gyri are involved in processing the form of many symbolic stimuli, but not specifically for stimuli with symbolic content. Selectivity for stimuli with symbolic content only emerges in the visual word network at the level of the middle temporal and inferior frontal gyri, but is specific for words and musical notation. Copyright © 2015 Elsevier Ltd. All rights reserved.

  13. Resting state neural networks for visual Chinese word processing in Chinese adults and children.

    PubMed

    Li, Ling; Liu, Jiangang; Chen, Feiyan; Feng, Lu; Li, Hong; Tian, Jie; Lee, Kang

    2013-07-01

    This study examined the resting state neural networks for visual Chinese word processing in Chinese children and adults. Both the functional connectivity (FC) and amplitude of low frequency fluctuation (ALFF) approaches were used to analyze the fMRI data collected when Chinese participants were not engaged in any specific explicit tasks. We correlated time series extracted from the visual word form area (VWFA) with those in other regions in the brain. We also performed ALFF analysis in the resting state FC networks. The FC results revealed that, regarding the functionally connected brain regions, there exist similar intrinsically organized resting state networks for visual Chinese word processing in adults and children, suggesting that such networks may already be functional after 3-4 years of informal exposure to reading plus 3-4 years formal schooling. The ALFF results revealed that children appear to recruit more neural resources than adults in generally reading-irrelevant brain regions. Differences between child and adult ALFF results suggest that children's intrinsic word processing network during the resting state, though similar in functional connectivity, is still undergoing development. Further exposure to visual words and experience with reading are needed for children to develop a mature intrinsic network for word processing. The developmental course of the intrinsically organized word processing network may parallel that of the explicit word processing network. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Atoms of recognition in human and computer vision.

    PubMed

    Ullman, Shimon; Assif, Liav; Fetaya, Ethan; Harari, Daniel

    2016-03-08

    Discovering the visual features and representations used by the brain to recognize objects is a central problem in the study of vision. Recently, neural network models of visual object recognition, including biological and deep network models, have shown remarkable progress and have begun to rival human performance in some challenging tasks. These models are trained on image examples and learn to extract features and representations and to use them for categorization. It remains unclear, however, whether the representations and learning processes discovered by current models are similar to those used by the human visual system. Here we show, by introducing and using minimal recognizable images, that the human visual system uses features and processes that are not used by current models and that are critical for recognition. We found by psychophysical studies that at the level of minimal recognizable images a minute change in the image can have a drastic effect on recognition, thus identifying features that are critical for the task. Simulations then showed that current models cannot explain this sensitivity to precise feature configurations and, more generally, do not learn to recognize minimal images at a human level. The role of the features shown here is revealed uniquely at the minimal level, where the contribution of each feature is essential. A full understanding of the learning and use of such features will extend our understanding of visual recognition and its cortical mechanisms and will enhance the capacity of computational models to learn from visual experience and to deal with recognition and detailed image interpretation.

  15. On Biological Network Visualization: Understanding Challenges, Measuring the Status Quo, and Estimating Saliency of Visual Attributes

    ERIC Educational Resources Information Center

    Gopal, Nikhil

    2017-01-01

    Biomedical research increasingly relies on the analysis and visualization of a wide range of collected data. However, for certain research questions, such as those investigating the interconnectedness of biological elements, the sheer quantity and variety of data results in rather uninterpretable--this is especially true for network visualization,…

  16. Putting age-related task activation into large-scale brain networks: A meta-analysis of 114 fMRI studies on healthy aging.

    PubMed

    Li, Hui-Jie; Hou, Xiao-Hui; Liu, Han-Hui; Yue, Chun-Lin; Lu, Guang-Ming; Zuo, Xi-Nian

    2015-10-01

    Normal aging is associated with cognitive decline and underlying brain dysfunction. Previous studies concentrated less on brain network changes at a systems level. Our goal was to examine these age-related changes of fMRI-derived activation with a common network parcellation of the human brain function, offering a systems-neuroscience perspective of healthy aging. We conducted a series of meta-analyses on a total of 114 studies that included 2035 older adults and 1845 young adults. Voxels showing significant age-related changes in activation were then overlaid onto seven commonly referenced neuronal networks. Older adults present moderate cognitive decline in behavioral performance during fMRI scanning, and hypo-activate the visual network and hyper-activate both the frontoparietal control and default mode networks. The degree of increased activation in frontoparietal network was associated with behavioral performance in older adults. Age-related changes in activation present different network patterns across cognitive domains. The systems neuroscience approach used here may be useful for elucidating the underlying network mechanisms of various brain plasticity processes during healthy aging. Copyright © 2015 The Authors. Published by Elsevier Ltd.. All rights reserved.

  17. Using the clustered circular layout as an informative method for visualizing protein-protein interaction networks.

    PubMed

    Fung, David C Y; Wilkins, Marc R; Hart, David; Hong, Seok-Hee

    2010-07-01

    The force-directed layout is commonly used in computer-generated visualizations of protein-protein interaction networks. While it is good for providing a visual outline of the protein complexes and their interactions, it has two limitations when used as a visual analysis method. The first is poor reproducibility. Repeated running of the algorithm does not necessarily generate the same layout, therefore, demanding cognitive readaptation on the investigator's part. The second limitation is that it does not explicitly display complementary biological information, e.g. Gene Ontology, other than the protein names or gene symbols. Here, we present an alternative layout called the clustered circular layout. Using the human DNA replication protein-protein interaction network as a case study, we compared the two network layouts for their merits and limitations in supporting visual analysis.

  18. A remote instruction system empowered by tightly shared haptic sensation

    NASA Astrophysics Data System (ADS)

    Nishino, Hiroaki; Yamaguchi, Akira; Kagawa, Tsuneo; Utsumiya, Kouichi

    2007-09-01

    We present a system to realize an on-line instruction environment among physically separated participants based on a multi-modal communication strategy. In addition to visual and acoustic information, commonly used communication modalities in network environments, our system provides a haptic channel to intuitively conveying partners' sense of touch. The human touch sensation, however, is very sensitive for delays and jitters in the networked virtual reality (NVR) systems. Therefore, a method to compensate for such negative factors needs to be provided. We show an NVR architecture to implement a basic framework that can be shared by various applications and effectively deals with the problems. We take a hybrid approach to implement both data consistency by client-server and scalability by peer-to-peer models. As an application system built on the proposed architecture, a remote instruction system targeted at teaching handwritten characters and line patterns on a Korea-Japan high-speed research network also is mentioned.

  19. Evaluation of Visualization Tools for Computer Network Defense Analysts: Display Design, Methods, and Results for a User Study

    DTIC Science & Technology

    2016-11-01

    Display Design, Methods , and Results for a User Study by Christopher J Garneau and Robert F Erbacher Approved for public...NOV 2016 US Army Research Laboratory Evaluation of Visualization Tools for Computer Network Defense Analysts: Display Design, Methods ...January 2013–September 2015 4. TITLE AND SUBTITLE Evaluation of Visualization Tools for Computer Network Defense Analysts: Display Design, Methods

  20. Objective video presentation QoE predictor for smart adaptive video streaming

    NASA Astrophysics Data System (ADS)

    Wang, Zhou; Zeng, Kai; Rehman, Abdul; Yeganeh, Hojatollah; Wang, Shiqi

    2015-09-01

    How to deliver videos to consumers over the network for optimal quality-of-experience (QoE) has been the central goal of modern video delivery services. Surprisingly, regardless of the large volume of videos being delivered everyday through various systems attempting to improve visual QoE, the actual QoE of end consumers is not properly assessed, not to say using QoE as the key factor in making critical decisions at the video hosting, network and receiving sites. Real-world video streaming systems typically use bitrate as the main video presentation quality indicator, but using the same bitrate to encode different video content could result in drastically different visual QoE, which is further affected by the display device and viewing condition of each individual consumer who receives the video. To correct this, we have to put QoE back to the driver's seat and redesign the video delivery systems. To achieve this goal, a major challenge is to find an objective video presentation QoE predictor that is accurate, fast, easy-to-use, display device adaptive, and provides meaningful QoE predictions across resolution and content. We propose to use the newly developed SSIMplus index (https://ece.uwaterloo.ca/~z70wang/research/ssimplus/) for this role. We demonstrate that based on SSIMplus, one can develop a smart adaptive video streaming strategy that leads to much smoother visual QoE impossible to achieve using existing adaptive bitrate video streaming approaches. Furthermore, SSIMplus finds many more applications, in live and file-based quality monitoring, in benchmarking video encoders and transcoders, and in guiding network resource allocations.

  1. CerebralWeb: a Cytoscape.js plug-in to visualize networks stratified by subcellular localization.

    PubMed

    Frias, Silvia; Bryan, Kenneth; Brinkman, Fiona S L; Lynn, David J

    2015-01-01

    CerebralWeb is a light-weight JavaScript plug-in that extends Cytoscape.js to enable fast and interactive visualization of molecular interaction networks stratified based on subcellular localization or other user-supplied annotation. The application is designed to be easily integrated into any website and is configurable to support customized network visualization. CerebralWeb also supports the automatic retrieval of Cerebral-compatible localizations for human, mouse and bovine genes via a web service and enables the automated parsing of Cytoscape compatible XGMML network files. CerebralWeb currently supports embedded network visualization on the InnateDB (www.innatedb.com) and Allergy and Asthma Portal (allergen.innatedb.com) database and analysis resources. Database tool URL: http://www.innatedb.com/CerebralWeb © The Author(s) 2015. Published by Oxford University Press.

  2. RICA: a reliable and image configurable arena for cyborg bumblebee based on CAN bus.

    PubMed

    Gong, Fan; Zheng, Nenggan; Xue, Lei; Xu, Kedi; Zheng, Xiaoxiang

    2014-01-01

    In this paper, we designed a reliable and image configurable flight arena, RICA, for developing cyborg bumblebees. To meet the spatial and temporal requirements of bumblebees, the Controller Area Network (CAN) bus is adopted to interconnect the LED display modules to ensure the reliability and real-time performance of the arena system. Easily-configurable interfaces on a desktop computer implemented by python scripts are provided to transmit the visual patterns to the LED distributor online and configure RICA dynamically. The new arena system will be a power tool to investigate the quantitative relationship between the visual inputs and induced flight behaviors and also will be helpful to the visual-motor research in other related fields.

  3. Space-Based Telescopes for the Actionable Refinement of Ephemeris Systems and Test Engineering

    DTIC Science & Technology

    2011-12-01

    Space Surveillance Network STARE Space-based Telescopes for the Actionable Refinement of Ephemeris STK Satellite Toolkit SV Space Vehicle TAMU...vacuum bake out and visual inspection. Additionally, it is prescribed that these tests be performed in accordance with GSFC-STD-7000, more commonly...environment that a FV will see in orbit. Tools such as Solid Works and NX-Ideas can be used to build CAD models to visually validate engineering

  4. 3DScapeCS: application of three dimensional, parallel, dynamic network visualization in Cytoscape

    PubMed Central

    2013-01-01

    Background The exponential growth of gigantic biological data from various sources, such as protein-protein interaction (PPI), genome sequences scaffolding, Mass spectrometry (MS) molecular networking and metabolic flux, demands an efficient way for better visualization and interpretation beyond the conventional, two-dimensional visualization tools. Results We developed a 3D Cytoscape Client/Server (3DScapeCS) plugin, which adopted Cytoscape in interpreting different types of data, and UbiGraph for three-dimensional visualization. The extra dimension is useful in accommodating, visualizing, and distinguishing large-scale networks with multiple crossed connections in five case studies. Conclusions Evaluation on several experimental data using 3DScapeCS and its special features, including multilevel graph layout, time-course data animation, and parallel visualization has proven its usefulness in visualizing complex data and help to make insightful conclusions. PMID:24225050

  5. Image Understanding by Image-Seeking Adaptive Networks (ISAN).

    DTIC Science & Technology

    1987-08-10

    our reserch on adaptive neural networks in the visual and sensory-motor cortex of cats. We demonstrate that, under certain conditions, plasticity is...understanding in organisms proceeds directly from adaptively seeking whole images and not via a preliminary analysis of elementary features, followed by object...empirical reserch has always been that ultimately any neural system has to serve behavior and that behavior serves survival. Evolutionary selection makes it

  6. Pattern recognition neural-net by spatial mapping of biology visual field

    NASA Astrophysics Data System (ADS)

    Lin, Xin; Mori, Masahiko

    2000-05-01

    The method of spatial mapping in biology vision field is applied to artificial neural networks for pattern recognition. By the coordinate transform that is called the complex-logarithm mapping and Fourier transform, the input images are transformed into scale- rotation- and shift- invariant patterns, and then fed into a multilayer neural network for learning and recognition. The results of computer simulation and an optical experimental system are described.

  7. Imaging of the interaction of cancer cells and the lymphatic system.

    PubMed

    Tran Cao, Hop S; McElroy, Michele; Kaushal, Sharmeela; Hoffman, Robert M; Bouvet, Michael

    2011-09-10

    A thorough understanding of the lymphatic system and its interaction with cancer cells is crucial to our ability to fight cancer metastasis. Efforts to study the lymphatic system had previously been limited by the inability to visualize the lymphatic system in vivo in real time. Fluorescence imaging can address these limitations and allow for visualization of lymphatic delivery and trafficking of cancer cells and potentially therapeutic agents as well. Here, we review recent articles in which antibody-fluorophore conjugates are used to label the lymphatic network and fluorescent proteins to label cancer cells in the evaluation of lymphatic delivery and imaging. Copyright © 2011 Elsevier B.V. All rights reserved.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    John Homer; Ashok Varikuti; Xinming Ou

    Various tools exist to analyze enterprise network systems and to produce attack graphs detailing how attackers might penetrate into the system. These attack graphs, however, are often complex and difficult to comprehend fully, and a human user may find it problematic to reach appropriate configuration decisions. This paper presents methodologies that can 1) automatically identify portions of an attack graph that do not help a user to understand the core security problems and so can be trimmed, and 2) automatically group similar attack steps as virtual nodes in a model of the network topology, to immediately increase the understandability ofmore » the data. We believe both methods are important steps toward improving visualization of attack graphs to make them more useful in configuration management for large enterprise networks. We implemented our methods using one of the existing attack-graph toolkits. Initial experimentation shows that the proposed approaches can 1) significantly reduce the complexity of attack graphs by trimming a large portion of the graph that is not needed for a user to understand the security problem, and 2) significantly increase the accessibility and understandability of the data presented in the attack graph by clearly showing, within a generated visualization of the network topology, the number and type of potential attacks to which each host is exposed.« less

  9. Immersive Molecular Visualization with Omnidirectional Stereoscopic Ray Tracing and Remote Rendering

    PubMed Central

    Stone, John E.; Sherman, William R.; Schulten, Klaus

    2016-01-01

    Immersive molecular visualization provides the viewer with intuitive perception of complex structures and spatial relationships that are of critical interest to structural biologists. The recent availability of commodity head mounted displays (HMDs) provides a compelling opportunity for widespread adoption of immersive visualization by molecular scientists, but HMDs pose additional challenges due to the need for low-latency, high-frame-rate rendering. State-of-the-art molecular dynamics simulations produce terabytes of data that can be impractical to transfer from remote supercomputers, necessitating routine use of remote visualization. Hardware-accelerated video encoding has profoundly increased frame rates and image resolution for remote visualization, however round-trip network latencies would cause simulator sickness when using HMDs. We present a novel two-phase rendering approach that overcomes network latencies with the combination of omnidirectional stereoscopic progressive ray tracing and high performance rasterization, and its implementation within VMD, a widely used molecular visualization and analysis tool. The new rendering approach enables immersive molecular visualization with rendering techniques such as shadows, ambient occlusion lighting, depth-of-field, and high quality transparency, that are particularly helpful for the study of large biomolecular complexes. We describe ray tracing algorithms that are used to optimize interactivity and quality, and we report key performance metrics of the system. The new techniques can also benefit many other application domains. PMID:27747138

  10. Computational Model of Primary Visual Cortex Combining Visual Attention for Action Recognition

    PubMed Central

    Shu, Na; Gao, Zhiyong; Chen, Xiangan; Liu, Haihua

    2015-01-01

    Humans can easily understand other people’s actions through visual systems, while computers cannot. Therefore, a new bio-inspired computational model is proposed in this paper aiming for automatic action recognition. The model focuses on dynamic properties of neurons and neural networks in the primary visual cortex (V1), and simulates the procedure of information processing in V1, which consists of visual perception, visual attention and representation of human action. In our model, a family of the three-dimensional spatial-temporal correlative Gabor filters is used to model the dynamic properties of the classical receptive field of V1 simple cell tuned to different speeds and orientations in time for detection of spatiotemporal information from video sequences. Based on the inhibitory effect of stimuli outside the classical receptive field caused by lateral connections of spiking neuron networks in V1, we propose surround suppressive operator to further process spatiotemporal information. Visual attention model based on perceptual grouping is integrated into our model to filter and group different regions. Moreover, in order to represent the human action, we consider the characteristic of the neural code: mean motion map based on analysis of spike trains generated by spiking neurons. The experimental evaluation on some publicly available action datasets and comparison with the state-of-the-art approaches demonstrate the superior performance of the proposed model. PMID:26132270

  11. Linking pain and the body: neural correlates of visually induced analgesia.

    PubMed

    Longo, Matthew R; Iannetti, Gian Domenico; Mancini, Flavia; Driver, Jon; Haggard, Patrick

    2012-02-22

    The visual context of seeing the body can reduce the experience of acute pain, producing a multisensory analgesia. Here we investigated the neural correlates of this "visually induced analgesia" using fMRI. We induced acute pain with an infrared laser while human participants looked either at their stimulated right hand or at another object. Behavioral results confirmed the expected analgesic effect of seeing the body, while fMRI results revealed an associated reduction of laser-induced activity in ipsilateral primary somatosensory cortex (SI) and contralateral operculoinsular cortex during the visual context of seeing the body. We further identified two known cortical networks activated by sensory stimulation: (1) a set of brain areas consistently activated by painful stimuli (the so-called "pain matrix"), and (2) an extensive set of posterior brain areas activated by the visual perception of the body ("visual body network"). Connectivity analyses via psychophysiological interactions revealed that the visual context of seeing the body increased effective connectivity (i.e., functional coupling) between posterior parietal nodes of the visual body network and the purported pain matrix. Increased connectivity with these posterior parietal nodes was seen for several pain-related regions, including somatosensory area SII, anterior and posterior insula, and anterior cingulate cortex. These findings suggest that visually induced analgesia does not involve an overall reduction of the cortical response elicited by laser stimulation, but is consequent to the interplay between the brain's pain network and a posterior network for body perception, resulting in modulation of the experience of pain.

  12. The Role of Architectural and Learning Constraints in Neural Network Models: A Case Study on Visual Space Coding.

    PubMed

    Testolin, Alberto; De Filippo De Grazia, Michele; Zorzi, Marco

    2017-01-01

    The recent "deep learning revolution" in artificial neural networks had strong impact and widespread deployment for engineering applications, but the use of deep learning for neurocomputational modeling has been so far limited. In this article we argue that unsupervised deep learning represents an important step forward for improving neurocomputational models of perception and cognition, because it emphasizes the role of generative learning as opposed to discriminative (supervised) learning. As a case study, we present a series of simulations investigating the emergence of neural coding of visual space for sensorimotor transformations. We compare different network architectures commonly used as building blocks for unsupervised deep learning by systematically testing the type of receptive fields and gain modulation developed by the hidden neurons. In particular, we compare Restricted Boltzmann Machines (RBMs), which are stochastic, generative networks with bidirectional connections trained using contrastive divergence, with autoencoders, which are deterministic networks trained using error backpropagation. For both learning architectures we also explore the role of sparse coding, which has been identified as a fundamental principle of neural computation. The unsupervised models are then compared with supervised, feed-forward networks that learn an explicit mapping between different spatial reference frames. Our simulations show that both architectural and learning constraints strongly influenced the emergent coding of visual space in terms of distribution of tuning functions at the level of single neurons. Unsupervised models, and particularly RBMs, were found to more closely adhere to neurophysiological data from single-cell recordings in the primate parietal cortex. These results provide new insights into how basic properties of artificial neural networks might be relevant for modeling neural information processing in biological systems.

  13. The Role of Architectural and Learning Constraints in Neural Network Models: A Case Study on Visual Space Coding

    PubMed Central

    Testolin, Alberto; De Filippo De Grazia, Michele; Zorzi, Marco

    2017-01-01

    The recent “deep learning revolution” in artificial neural networks had strong impact and widespread deployment for engineering applications, but the use of deep learning for neurocomputational modeling has been so far limited. In this article we argue that unsupervised deep learning represents an important step forward for improving neurocomputational models of perception and cognition, because it emphasizes the role of generative learning as opposed to discriminative (supervised) learning. As a case study, we present a series of simulations investigating the emergence of neural coding of visual space for sensorimotor transformations. We compare different network architectures commonly used as building blocks for unsupervised deep learning by systematically testing the type of receptive fields and gain modulation developed by the hidden neurons. In particular, we compare Restricted Boltzmann Machines (RBMs), which are stochastic, generative networks with bidirectional connections trained using contrastive divergence, with autoencoders, which are deterministic networks trained using error backpropagation. For both learning architectures we also explore the role of sparse coding, which has been identified as a fundamental principle of neural computation. The unsupervised models are then compared with supervised, feed-forward networks that learn an explicit mapping between different spatial reference frames. Our simulations show that both architectural and learning constraints strongly influenced the emergent coding of visual space in terms of distribution of tuning functions at the level of single neurons. Unsupervised models, and particularly RBMs, were found to more closely adhere to neurophysiological data from single-cell recordings in the primate parietal cortex. These results provide new insights into how basic properties of artificial neural networks might be relevant for modeling neural information processing in biological systems. PMID:28377709

  14. Sonification of network traffic flow for monitoring and situational awareness

    PubMed Central

    2018-01-01

    Maintaining situational awareness of what is happening within a computer network is challenging, not only because the behaviour happens within machines, but also because data traffic speeds and volumes are beyond human ability to process. Visualisation techniques are widely used to present information about network traffic dynamics. Although they provide operators with an overall view and specific information about particular traffic or attacks on the network, they often still fail to represent the events in an understandable way. Also, because they require visual attention they are not well suited to continuous monitoring scenarios in which network administrators must carry out other tasks. Here we present SoNSTAR (Sonification of Networks for SiTuational AwaReness), a real-time sonification system for monitoring computer networks to support network administrators’ situational awareness. SoNSTAR provides an auditory representation of all the TCP/IP traffic within a network based on the different traffic flows between between network hosts. A user study showed that SoNSTAR raises situational awareness levels by enabling operators to understand network behaviour and with the benefit of lower workload demands (as measured by the NASA TLX method) than visual techniques. SoNSTAR identifies network traffic features by inspecting the status flags of TCP/IP packet headers. Combinations of these features define particular traffic events which are mapped to recorded sounds to generate a soundscape that represents the real-time status of the network traffic environment. The sequence, timing, and loudness of the different sounds allow the network to be monitored and anomalous behaviour to be detected without the need to continuously watch a monitor screen. PMID:29672543

  15. Sonification of network traffic flow for monitoring and situational awareness.

    PubMed

    Debashi, Mohamed; Vickers, Paul

    2018-01-01

    Maintaining situational awareness of what is happening within a computer network is challenging, not only because the behaviour happens within machines, but also because data traffic speeds and volumes are beyond human ability to process. Visualisation techniques are widely used to present information about network traffic dynamics. Although they provide operators with an overall view and specific information about particular traffic or attacks on the network, they often still fail to represent the events in an understandable way. Also, because they require visual attention they are not well suited to continuous monitoring scenarios in which network administrators must carry out other tasks. Here we present SoNSTAR (Sonification of Networks for SiTuational AwaReness), a real-time sonification system for monitoring computer networks to support network administrators' situational awareness. SoNSTAR provides an auditory representation of all the TCP/IP traffic within a network based on the different traffic flows between between network hosts. A user study showed that SoNSTAR raises situational awareness levels by enabling operators to understand network behaviour and with the benefit of lower workload demands (as measured by the NASA TLX method) than visual techniques. SoNSTAR identifies network traffic features by inspecting the status flags of TCP/IP packet headers. Combinations of these features define particular traffic events which are mapped to recorded sounds to generate a soundscape that represents the real-time status of the network traffic environment. The sequence, timing, and loudness of the different sounds allow the network to be monitored and anomalous behaviour to be detected without the need to continuously watch a monitor screen.

  16. Creating a New Definition of Library Cooperation: Past, Present, and Future Models.

    ERIC Educational Resources Information Center

    Lenzini, Rebecca T.; Shaw, Ward

    1991-01-01

    Describes the creation and purpose of the Colorado Alliance of Research Libraries (CARL), the subsequent development of CARL Systems, and its current research projects. Topics discussed include online catalogs; UnCover, a journal article database; full text data; document delivery; visual images in computer systems; networks; and implications for…

  17. Identifying compromised systems through correlation of suspicious traffic from malware behavioral analysis

    NASA Astrophysics Data System (ADS)

    Camilo, Ana E. F.; Grégio, André; Santos, Rafael D. C.

    2016-05-01

    Malware detection may be accomplished through the analysis of their infection behavior. To do so, dynamic analysis systems run malware samples and extract their operating system activities and network traffic. This traffic may represent malware accessing external systems, either to steal sensitive data from victims or to fetch other malicious artifacts (configuration files, additional modules, commands). In this work, we propose the use of visualization as a tool to identify compromised systems based on correlating malware communications in the form of graphs and finding isomorphisms between them. We produced graphs from over 6 thousand distinct network traffic files captured during malware execution and analyzed the existing relationships among malware samples and IP addresses.

  18. Ten Commandments for Microcomputer Facility Planners.

    ERIC Educational Resources Information Center

    Espinosa, Leonard J.

    1991-01-01

    Presents factors involved in designing a microcomputer facility, including how computers will be used in the instructional program; educational specifications; planning committees; user input; quality of purchases; visual supervision considerations; location; workstation design; turnkey systems; electrical requirements; local area networks;…

  19. Visual traffic jam analysis based on trajectory data.

    PubMed

    Wang, Zuchao; Lu, Min; Yuan, Xiaoru; Zhang, Junping; van de Wetering, Huub

    2013-12-01

    In this work, we present an interactive system for visual analysis of urban traffic congestion based on GPS trajectories. For these trajectories we develop strategies to extract and derive traffic jam information. After cleaning the trajectories, they are matched to a road network. Subsequently, traffic speed on each road segment is computed and traffic jam events are automatically detected. Spatially and temporally related events are concatenated in, so-called, traffic jam propagation graphs. These graphs form a high-level description of a traffic jam and its propagation in time and space. Our system provides multiple views for visually exploring and analyzing the traffic condition of a large city as a whole, on the level of propagation graphs, and on road segment level. Case studies with 24 days of taxi GPS trajectories collected in Beijing demonstrate the effectiveness of our system.

  20. Visualization of the microcirculatory network in skin by high frequency optoacoustic mesoscopy

    NASA Astrophysics Data System (ADS)

    Schwarz, Mathias; Aguirre, Juan; Buehler, Andreas; Omar, Murad; Ntziachristos, Vasilis

    2015-07-01

    Optoacoustic (photoacoustic) imaging has a high potential for imaging melanin-rich structures in skin and the microvasculature of the dermis due to the natural chromophores (de)oxyhemoglobin, and melanin. The vascular network in human dermis comprises a large network of arterioles, capillaries, and venules, ranging from 5 μm to more than 100 μm in diameter. The frequency spectrum of the microcirculatory network in human skin is intrinsically broadband, due to the large variety in size of absorbers. In our group we have developed raster-scan optoacoustic mesoscopy (RSOM) that applies a 100 MHz transducer with ultra-wide bandwidth in raster-scan mode achieving lateral resolution of 18 μm. In this study, we applied high frequency RSOM to imaging human skin in a healthy volunteer. We analyzed the frequency spectrum of anatomical structures with respect to depth and show that frequencies >60 MHz contain valuable information of structures in the epidermis and the microvasculature of the papillary dermis. We illustrate that RSOM is capable of visualizing the fine vascular network at and beneath the epidermal-dermal junction, revealing the vascular fingerprint of glabrous skin, as well as the larger venules deeper inside the dermis. We evaluate the ability of the RSOM system in measuring epidermal thickness in both hairy and glabrous skin. Finally, we showcase the capability of RSOM in visualizing benign nevi that will potentially help in imaging the penetration depth of melanoma.

  1. SPIKE – a database, visualization and analysis tool of cellular signaling pathways

    PubMed Central

    Elkon, Ran; Vesterman, Rita; Amit, Nira; Ulitsky, Igor; Zohar, Idan; Weisz, Mali; Mass, Gilad; Orlev, Nir; Sternberg, Giora; Blekhman, Ran; Assa, Jackie; Shiloh, Yosef; Shamir, Ron

    2008-01-01

    Background Biological signaling pathways that govern cellular physiology form an intricate web of tightly regulated interlocking processes. Data on these regulatory networks are accumulating at an unprecedented pace. The assimilation, visualization and interpretation of these data have become a major challenge in biological research, and once met, will greatly boost our ability to understand cell functioning on a systems level. Results To cope with this challenge, we are developing the SPIKE knowledge-base of signaling pathways. SPIKE contains three main software components: 1) A database (DB) of biological signaling pathways. Carefully curated information from the literature and data from large public sources constitute distinct tiers of the DB. 2) A visualization package that allows interactive graphic representations of regulatory interactions stored in the DB and superposition of functional genomic and proteomic data on the maps. 3) An algorithmic inference engine that analyzes the networks for novel functional interplays between network components. SPIKE is designed and implemented as a community tool and therefore provides a user-friendly interface that allows registered users to upload data to SPIKE DB. Our vision is that the DB will be populated by a distributed and highly collaborative effort undertaken by multiple groups in the research community, where each group contributes data in its field of expertise. Conclusion The integrated capabilities of SPIKE make it a powerful platform for the analysis of signaling networks and the integration of knowledge on such networks with omics data. PMID:18289391

  2. Visualizing Dynamic Weather and Ocean Data in Google Earth

    NASA Astrophysics Data System (ADS)

    Castello, C.; Giencke, P.

    2008-12-01

    Katrina. Climate change. Rising sea levels. Low lake levels. These headliners, and countless others like them, underscore the need to better understand our changing oceans and lakes. Over the past decade, efforts such as the Global Ocean Observing System (GOOS) have added to this understanding, through the creation of interoperable ocean observing systems. These systems, including buoy networks, gliders, UAV's, etc, have resulted in a dramatic increase in the amount of Earth observation data available to the public. Unfortunately, these data tend to be restrictive to mass consumption, owing to large file sizes, incompatible formats, and/or a dearth of user friendly visualization software. Google Earth offers a flexible way to visualize Earth observation data. Marrying high resolution orthoimagery, user friendly query and navigation tools, and the power of OGC's KML standard, Google Earth can make observation data universally understandable and accessible. This presentation will feature examples of meteorological and oceanographic data visualized using KML and Google Earth, along with tools and tips for integrating other such environmental datasets.

  3. Network Analysis of Drug-target Interactions: A Study on FDA-approved New Molecular Entities Between 2000 to 2015.

    PubMed

    Lin, Hui-Heng; Zhang, Le-Le; Yan, Ru; Lu, Jin-Jian; Hu, Yuanjia

    2017-09-25

    The U.S. Food and Drug Administration (FDA) approves new drugs every year. Drug targets are some of the most important interactive molecules for drugs, as they have a significant impact on the therapeutic effects of drugs. In this work, we thoroughly analyzed the data of small molecule drugs approved by the U.S. FDA between 2000 and 2015. Specifically, we focused on seven classes of new molecular entity (NME) classified by the anatomic therapeutic chemical (ATC) classification system. They were NMEs and their corresponding targets for the cardiovascular system, respiratory system, nerve system, general anti-infective systemic, genito-urinary system and sex hormones, alimentary tract and metabolisms, and antineoplastic and immunomodulating agents. To study the drug-target interaction on the systems level, we employed network topological analysis and multipartite network projections. As a result, the drug-target relations of different kinds of drugs were comprehensively characterized and global pictures of drug-target, drug-drug, and target-target interactions were visualized and analyzed from the perspective of network models.

  4. Top-down alpha oscillatory network interactions during visuospatial attention orienting.

    PubMed

    Doesburg, Sam M; Bedo, Nicolas; Ward, Lawrence M

    2016-05-15

    Neuroimaging and lesion studies indicate that visual attention is controlled by a distributed network of brain areas. The covert control of visuospatial attention has also been associated with retinotopic modulation of alpha-band oscillations within early visual cortex, which are thought to underlie inhibition of ignored areas of visual space. The relation between distributed networks mediating attention control and more focal oscillatory mechanisms, however, remains unclear. The present study evaluated the hypothesis that alpha-band, directed, network interactions within the attention control network are systematically modulated by the locus of visuospatial attention. We localized brain areas involved in visuospatial attention orienting using magnetoencephalographic (MEG) imaging and investigated alpha-band Granger-causal interactions among activated regions using narrow-band transfer entropy. The deployment of attention to one side of visual space was indexed by lateralization of alpha power changes between about 400ms and 700ms post-cue onset. The changes in alpha power were associated, in the same time period, with lateralization of anterior-to-posterior information flow in the alpha-band from various brain areas involved in attention control, including the anterior cingulate cortex, left middle and inferior frontal gyri, left superior temporal gyrus, and right insula, and inferior parietal lobule, to early visual areas. We interpreted these results to indicate that distributed network interactions mediated by alpha oscillations exert top-down influences on early visual cortex to modulate inhibition of processing for ignored areas of visual space. Copyright © 2016. Published by Elsevier Inc.

  5. An insect-inspired model for visual binding II: functional analysis and visual attention.

    PubMed

    Northcutt, Brandon D; Higgins, Charles M

    2017-04-01

    We have developed a neural network model capable of performing visual binding inspired by neuronal circuitry in the optic glomeruli of flies: a brain area that lies just downstream of the optic lobes where early visual processing is performed. This visual binding model is able to detect objects in dynamic image sequences and bind together their respective characteristic visual features-such as color, motion, and orientation-by taking advantage of their common temporal fluctuations. Visual binding is represented in the form of an inhibitory weight matrix which learns over time which features originate from a given visual object. In the present work, we show that information represented implicitly in this weight matrix can be used to explicitly count the number of objects present in the visual image, to enumerate their specific visual characteristics, and even to create an enhanced image in which one particular object is emphasized over others, thus implementing a simple form of visual attention. Further, we present a detailed analysis which reveals the function and theoretical limitations of the visual binding network and in this context describe a novel network learning rule which is optimized for visual binding.

  6. Altered intrinsic functional brain architecture in female patients with bulimia nervosa

    PubMed Central

    Wang, Li; Kong, Qing-Mei; Li, Ke; Li, Xue-Ni; Zeng, Ya-Wei; Chen, Chao; Qian, Ying; Feng, Shi-Jie; Li, Ji-Tao; Su, Yun’Ai; Correll, Christoph U.; Mitchell, Philip B.; Yan, Chao-Gan; Zhang, Da-Rong; Si, Tian-Mei

    2017-01-01

    Background Bulimia nervosa is a severe psychiatric syndrome with uncertain pathogenesis. Neural systems involved in sensorimotor and visual processing, reward and impulsive control may contribute to the binge eating and purging behaviours characterizing bulimia nervosa. However, little is known about the alterations of functional organization of whole brain networks in individuals with this disorder. Methods We used resting-state functional MRI and graph theory to characterize functional brain networks of unmedicated women with bulimia nervosa and healthy women. Results We included 44 unmedicated women with bulimia nervosa and 44 healthy women in our analyses. Women with bulimia nervosa showed increased clustering coefficient and path length compared with control women. The nodal strength in patients with the disorder was higher in the sensorimotor and visual regions as well as the precuneus, but lower in several subcortical regions, such as the hippocampus, parahippocampal gyrus and orbitofrontal cortex. Patients also showed hyperconnectivity primarily involving sensorimotor and unimodal visual association regions, but hypoconnectivity involving subcortical (striatum, thalamus), limbic (amygdala, hippocampus) and paralimbic (orbitofrontal cortex, parahippocampal gyrus) regions. The topological aberrations correlated significantly with scores of bulimia and drive for thinness and with body mass index. Limitations We reruited patients with only acute bulimia nervosa, so it is unclear whether the topological abnormalities comprise vulnerability markers for the disorder developing or the changes associated with illness state. Conclusion Our findings show altered intrinsic functional brain architecture, specifically abnormal global and local efficiency, as well as nodal- and network-level connectivity across sensorimotor, visual, subcortical and limbic systems in women with bulimia nervosa, suggesting that it is a disorder of dysfunctional integration among large-scale distributed brain regions. These abnormalities contribute to more comprehensive understanding of the neural mechanism underlying pathological eating and body perception in women with bulimia nervosa. PMID:28949286

  7. Altered intrinsic functional brain architecture in female patients with bulimia nervosa.

    PubMed

    Wang, Li; Kong, Qing-Mei; Li, Ke; Li, Xue-Ni; Zeng, Ya-Wei; Chen, Chao; Qian, Ying; Feng, Shi-Jie; Li, Ji-Tao; Su, Yun'Ai; Correll, Christoph U; Mitchell, Philip B; Yan, Chao-Gan; Zhang, Da-Rong; Si, Tian-Mei

    2017-11-01

    Bulimia nervosa is a severe psychiatric syndrome with uncertain pathogenesis. Neural systems involved in sensorimotor and visual processing, reward and impulsive control may contribute to the binge eating and purging behaviours characterizing bulimia nervosa. However, little is known about the alterations of functional organization of whole brain networks in individuals with this disorder. We used resting-state functional MRI and graph theory to characterize functional brain networks of unmedicated women with bulimia nervosa and healthy women. We included 44 unmedicated women with bulimia nervosa and 44 healthy women in our analyses. Women with bulimia nervosa showed increased clustering coefficient and path length compared with control women. The nodal strength in patients with the disorder was higher in the sensorimotor and visual regions as well as the precuneus, but lower in several subcortical regions, such as the hippocampus, parahippocampal gyrus and orbitofrontal cortex. Patients also showed hyperconnectivity primarily involving sensorimotor and unimodal visual association regions, but hypoconnectivity involving subcortical (striatum, thalamus), limbic (amygdala, hippocampus) and paralimbic (orbitofrontal cortex, parahippocampal gyrus) regions. The topological aberrations correlated significantly with scores of bulimia and drive for thinness and with body mass index. We reruited patients with only acute bulimia nervosa, so it is unclear whether the topological abnormalities comprise vulnerability markers for the disorder developing or the changes associated with illness state. Our findings show altered intrinsic functional brain architecture, specifically abnormal global and local efficiency, as well as nodal- and network-level connectivity across sensorimotor, visual, subcortical and limbic systems in women with bulimia nervosa, suggesting that it is a disorder of dysfunctional integration among large-scale distributed brain regions. These abnormalities contribute to more comprehensive understanding of the neural mechanism underlying pathological eating and body perception in women with bulimia nervosa.

  8. Conflicting Demands of Abstract and Specific Visual Object Processing Resolved by Fronto-Parietal Networks

    PubMed Central

    McMenamin, Brenton W.; Marsolek, Chad J.; Morseth, Brianna K.; Speer, MacKenzie F.; Burton, Philip C.; Burgund, E. Darcy

    2016-01-01

    Object categorization and exemplar identification place conflicting demands on the visual system, yet humans easily perform these fundamentally contradictory tasks. Previous studies suggest the existence of dissociable visual processing subsystems to accomplish the two abilities – an abstract category (AC) subsystem that operates effectively in the left hemisphere, and a specific exemplar (SE) subsystem that operates effectively in the right hemisphere. This multiple subsystems theory explains a range of visual abilities, but previous studies have not explored what mechanisms exist for coordinating the function of multiple subsystems and/or resolving the conflicts that would arise between them. We collected functional MRI data while participants performed two variants of a cue-probe working memory task that required AC or SE processing. During the maintenance phase of the task, the bilateral intraparietal sulcus (IPS) exhibited hemispheric asymmetries in functional connectivity consistent with exerting proactive control over the two visual subsystems: greater connectivity to the left hemisphere during the AC task, and greater connectivity to the right hemisphere during the SE task. Moreover, probe-evoked activation revealed activity in a broad fronto-parietal network (containing IPS) associated with reactive control when the two visual subsystems were in conflict, and variations in this conflict signal across trials was related to the visual similarity of the cue/probe stimulus pairs. Although many studies have confirmed the existence of multiple visual processing subsystems, this study is the first to identify the mechanisms responsible for coordinating their operations. PMID:26883940

  9. Conflicting demands of abstract and specific visual object processing resolved by frontoparietal networks.

    PubMed

    McMenamin, Brenton W; Marsolek, Chad J; Morseth, Brianna K; Speer, MacKenzie F; Burton, Philip C; Burgund, E Darcy

    2016-06-01

    Object categorization and exemplar identification place conflicting demands on the visual system, yet humans easily perform these fundamentally contradictory tasks. Previous studies suggest the existence of dissociable visual processing subsystems to accomplish the two abilities-an abstract category (AC) subsystem that operates effectively in the left hemisphere and a specific exemplar (SE) subsystem that operates effectively in the right hemisphere. This multiple subsystems theory explains a range of visual abilities, but previous studies have not explored what mechanisms exist for coordinating the function of multiple subsystems and/or resolving the conflicts that would arise between them. We collected functional MRI data while participants performed two variants of a cue-probe working memory task that required AC or SE processing. During the maintenance phase of the task, the bilateral intraparietal sulcus (IPS) exhibited hemispheric asymmetries in functional connectivity consistent with exerting proactive control over the two visual subsystems: greater connectivity to the left hemisphere during the AC task, and greater connectivity to the right hemisphere during the SE task. Moreover, probe-evoked activation revealed activity in a broad frontoparietal network (containing IPS) associated with reactive control when the two visual subsystems were in conflict, and variations in this conflict signal across trials was related to the visual similarity of the cue-probe stimulus pairs. Although many studies have confirmed the existence of multiple visual processing subsystems, this study is the first to identify the mechanisms responsible for coordinating their operations.

  10. FloVis: Leveraging Visualization to Protect Sensitive Network Infrastructure

    DTIC Science & Technology

    2010-11-01

    words, we are clustering the hourly web surfing patterns of users on a small private network. The data in this case is filtered NetFlow records...Entity-based NetFlow Visualization Utility for Identifying Intrusive Behavior. In Goodall et al. (eds.), Mathematics and Visualization (Proceedings

  11. Neural networks for satellite remote sensing and robotic sensor interpretation

    NASA Astrophysics Data System (ADS)

    Martens, Siegfried

    Remote sensing of forests and robotic sensor fusion can be viewed, in part, as supervised learning problems, mapping from sensory input to perceptual output. This dissertation develops ARTMAP neural networks for real-time category learning, pattern recognition, and prediction tailored to remote sensing and robotics applications. Three studies are presented. The first two use ARTMAP to create maps from remotely sensed data, while the third uses an ARTMAP system for sensor fusion on a mobile robot. The first study uses ARTMAP to predict vegetation mixtures in the Plumas National Forest based on spectral data from the Landsat Thematic Mapper satellite. While most previous ARTMAP systems have predicted discrete output classes, this project develops new capabilities for multi-valued prediction. On the mixture prediction task, the new network is shown to perform better than maximum likelihood and linear mixture models. The second remote sensing study uses an ARTMAP classification system to evaluate the relative importance of spectral and terrain data for map-making. This project has produced a large-scale map of remotely sensed vegetation in the Sierra National Forest. Network predictions are validated with ground truth data, and maps produced using the ARTMAP system are compared to a map produced by human experts. The ARTMAP Sierra map was generated in an afternoon, while the labor intensive expert method required nearly a year to perform the same task. The robotics research uses an ARTMAP system to integrate visual information and ultrasonic sensory information on a B14 mobile robot. The goal is to produce a more accurate measure of distance than is provided by the raw sensors. ARTMAP effectively combines sensory sources both within and between modalities. The improved distance percept is used to produce occupancy grid visualizations of the robot's environment. The maps produced point to specific problems of raw sensory information processing and demonstrate the benefits of using a neural network system for sensor fusion.

  12. Comprehensive Reconstruction and Visualization of Non-Coding Regulatory Networks in Human

    PubMed Central

    Bonnici, Vincenzo; Russo, Francesco; Bombieri, Nicola; Pulvirenti, Alfredo; Giugno, Rosalba

    2014-01-01

    Research attention has been powered to understand the functional roles of non-coding RNAs (ncRNAs). Many studies have demonstrated their deregulation in cancer and other human disorders. ncRNAs are also present in extracellular human body fluids such as serum and plasma, giving them a great potential as non-invasive biomarkers. However, non-coding RNAs have been relatively recently discovered and a comprehensive database including all of them is still missing. Reconstructing and visualizing the network of ncRNAs interactions are important steps to understand their regulatory mechanism in complex systems. This work presents ncRNA-DB, a NoSQL database that integrates ncRNAs data interactions from a large number of well established on-line repositories. The interactions involve RNA, DNA, proteins, and diseases. ncRNA-DB is available at http://ncrnadb.scienze.univr.it/ncrnadb/. It is equipped with three interfaces: web based, command-line, and a Cytoscape app called ncINetView. By accessing only one resource, users can search for ncRNAs and their interactions, build a network annotated with all known ncRNAs and associated diseases, and use all visual and mining features available in Cytoscape. PMID:25540777

  13. Comprehensive reconstruction and visualization of non-coding regulatory networks in human.

    PubMed

    Bonnici, Vincenzo; Russo, Francesco; Bombieri, Nicola; Pulvirenti, Alfredo; Giugno, Rosalba

    2014-01-01

    Research attention has been powered to understand the functional roles of non-coding RNAs (ncRNAs). Many studies have demonstrated their deregulation in cancer and other human disorders. ncRNAs are also present in extracellular human body fluids such as serum and plasma, giving them a great potential as non-invasive biomarkers. However, non-coding RNAs have been relatively recently discovered and a comprehensive database including all of them is still missing. Reconstructing and visualizing the network of ncRNAs interactions are important steps to understand their regulatory mechanism in complex systems. This work presents ncRNA-DB, a NoSQL database that integrates ncRNAs data interactions from a large number of well established on-line repositories. The interactions involve RNA, DNA, proteins, and diseases. ncRNA-DB is available at http://ncrnadb.scienze.univr.it/ncrnadb/. It is equipped with three interfaces: web based, command-line, and a Cytoscape app called ncINetView. By accessing only one resource, users can search for ncRNAs and their interactions, build a network annotated with all known ncRNAs and associated diseases, and use all visual and mining features available in Cytoscape.

  14. Orthoscape: a cytoscape application for grouping and visualization KEGG based gene networks by taxonomy and homology principles.

    PubMed

    Mustafin, Zakhar Sergeevich; Lashin, Sergey Alexandrovich; Matushkin, Yury Georgievich; Gunbin, Konstantin Vladimirovich; Afonnikov, Dmitry Arkadievich

    2017-01-27

    There are many available software tools for visualization and analysis of biological networks. Among them, Cytoscape ( http://cytoscape.org/ ) is one of the most comprehensive packages, with many plugins and applications which extends its functionality by providing analysis of protein-protein interaction, gene regulatory and gene co-expression networks, metabolic, signaling, neural as well as ecological-type networks including food webs, communities networks etc. Nevertheless, only three plugins tagged 'network evolution' found in Cytoscape official app store and in literature. We have developed a new Cytoscape 3.0 application Orthoscape aimed to facilitate evolutionary analysis of gene networks and visualize the results. Orthoscape aids in analysis of evolutionary information available for gene sets and networks by highlighting: (1) the orthology relationships between genes; (2) the evolutionary origin of gene network components; (3) the evolutionary pressure mode (diversifying or stabilizing, negative or positive selection) of orthologous groups in general and/or branch-oriented mode. The distinctive feature of Orthoscape is the ability to control all data analysis steps via user-friendly interface. Orthoscape allows its users to analyze gene networks or separated gene sets in the context of evolution. At each step of data analysis, Orthoscape also provides for convenient visualization and data manipulation.

  15. AllAboard: Visual Exploration of Cellphone Mobility Data to Optimise Public Transport.

    PubMed

    Di Lorenzo, G; Sbodio, M; Calabrese, F; Berlingerio, M; Pinelli, F; Nair, R

    2016-02-01

    The deep penetration of mobile phones offers cities the ability to opportunistically monitor citizens' mobility and use data-driven insights to better plan and manage services. With large scale data on mobility patterns, operators can move away from the costly, mostly survey based, transportation planning processes, to a more data-centric view, that places the instrumented user at the center of development. In this framework, using mobile phone data to perform transit analysis and optimization represents a new frontier with significant societal impact, especially in developing countries. In this paper we present AllAboard, an intelligent tool that analyses cellphone data to help city authorities in visually exploring urban mobility and optimizing public transport. This is performed within a self contained tool, as opposed to the current solutions which rely on a combination of several distinct tools for analysis, reporting, optimisation and planning. An interactive user interface allows transit operators to visually explore the travel demand in both space and time, correlate it with the transit network, and evaluate the quality of service that a transit network provides to the citizens at very fine grain. Operators can visually test scenarios for transit network improvements, and compare the expected impact on the travellers' experience. The system has been tested using real telecommunication data for the city of Abidjan, Ivory Coast, and evaluated from a data mining, optimisation and user prospective.

  16. Resting-state functional connectivity in multiple sclerosis: an examination of group differences and individual differences.

    PubMed

    Janssen, Alisha L; Boster, Aaron; Patterson, Beth A; Abduljalil, Amir; Prakash, Ruchika Shaurya

    2013-11-01

    Multiple sclerosis (MS) is a neurodegenerative, inflammatory disease of the central nervous system, resulting in physical and cognitive disturbances. The goal of the current study was to examine the association between network integrity and composite measures of cognition and disease severity in individuals with relapsing-remitting MS (RRMS), relative to healthy controls. All participants underwent a neuropsychological and neuroimaging session, where resting-state data was collected. Independent component analysis and dual regression were employed to examine network integrity in individuals with MS, relative to healthy controls. The MS sample exhibited less connectivity in the motor and visual networks, relative to healthy controls, after controlling for group differences in gray matter volume. However, no alterations were observed in the frontoparietal, executive control, or default-mode networks, despite previous evidence of altered neuronal patterns during tasks of exogenous processing. Whole-brain, voxel-wise regression analyses with disease severity and processing speed composites were also performed to elucidate the brain-behavior relationship with neuronal network integrity. Individuals with higher levels of disease severity demonstrated reduced intra-network connectivity of the motor network, and the executive control network, while higher disease burden was associated with greater inter-network connectivity between the medial visual network and areas involved in visuomotor learning. Our findings underscore the importance of examining resting-state oscillations in this population, both as a biomarker of disease progression and a potential target for therapeutic intervention. Copyright © 2013 Elsevier Ltd. All rights reserved.

  17. Report on the Dagstuhl Seminar on Visualization and Monitoring of Network Traffic

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Keim, Daniel; Pras, Aiko; Schonwalder, Jurgen

    2011-01-26

    The Dagstuhl Seminar on Visualization and Monitoring of Network Traffic [1] took place May 17-20, 2009 in Dagstuhl, Germany. Dagstuhl seminars promote personal interaction and open discussion of results as well as new ideas. Unlike at most conferences, the focus is not solely on the presentation of established results but to equal parts on results, ideas, sketches, and open problems. The aim of this particular seminar was to bring together experts from the information visualization community and the networking community in order to discuss the state of the art of monitoring and visualization of network traffic. People from the differentmore » research communities involved jointly organized the seminar. The co-chairs of the seminar from the networking community were Aiko Pras (University of Twente) and Jürgen Schönwälder (Jacobs University Bremen). The co-chairs from the visualization community were Daniel A. Keim (University of Konstanz) and Pak Chung Wong (Pacific Northwest National Lab). Florian Mansmann (University of Konstanz) helped with producing this report. The seminar was organized and supported by Schloss Dagstuhl and the EC IST-EMANICS Network of Excellence [1].« less

  18. Visual attention capacity: a review of TVA-based patient studies.

    PubMed

    Habekost, Thomas; Starrfelt, Randi

    2009-02-01

    Psychophysical studies have identified two distinct limitations of visual attention capacity: processing speed and apprehension span. Using a simple test, these cognitive factors can be analyzed by Bundesen's Theory of Visual Attention (TVA). The method has strong specificity and sensitivity, and measurements are highly reliable. As the method is theoretically founded, it also has high validity. TVA-based assessment has recently been used to investigate a broad range of neuropsychological and neurological conditions. We present the method, including the experimental paradigm and practical guidelines to patient testing, and review existing TVA-based patient studies organized by lesion anatomy. Lesions in three anatomical regions affect visual capacity: The parietal lobes, frontal cortex and basal ganglia, and extrastriate cortex. Visual capacity thus depends on large, bilaterally distributed anatomical networks that include several regions outside the visual system. The two visual capacity parameters are functionally separable, but seem to rely on largely overlapping brain areas.

  19. Visual affective classification by combining visual and text features.

    PubMed

    Liu, Ningning; Wang, Kai; Jin, Xin; Gao, Boyang; Dellandréa, Emmanuel; Chen, Liming

    2017-01-01

    Affective analysis of images in social networks has drawn much attention, and the texts surrounding images are proven to provide valuable semantic meanings about image content, which can hardly be represented by low-level visual features. In this paper, we propose a novel approach for visual affective classification (VAC) task. This approach combines visual representations along with novel text features through a fusion scheme based on Dempster-Shafer (D-S) Evidence Theory. Specifically, we not only investigate different types of visual features and fusion methods for VAC, but also propose textual features to effectively capture emotional semantics from the short text associated to images based on word similarity. Experiments are conducted on three public available databases: the International Affective Picture System (IAPS), the Artistic Photos and the MirFlickr Affect set. The results demonstrate that the proposed approach combining visual and textual features provides promising results for VAC task.

  20. Visual affective classification by combining visual and text features

    PubMed Central

    Liu, Ningning; Wang, Kai; Jin, Xin; Gao, Boyang; Dellandréa, Emmanuel; Chen, Liming

    2017-01-01

    Affective analysis of images in social networks has drawn much attention, and the texts surrounding images are proven to provide valuable semantic meanings about image content, which can hardly be represented by low-level visual features. In this paper, we propose a novel approach for visual affective classification (VAC) task. This approach combines visual representations along with novel text features through a fusion scheme based on Dempster-Shafer (D-S) Evidence Theory. Specifically, we not only investigate different types of visual features and fusion methods for VAC, but also propose textual features to effectively capture emotional semantics from the short text associated to images based on word similarity. Experiments are conducted on three public available databases: the International Affective Picture System (IAPS), the Artistic Photos and the MirFlickr Affect set. The results demonstrate that the proposed approach combining visual and textual features provides promising results for VAC task. PMID:28850566

  1. Enabling Comprehension of Patient Subgroups and Characteristics in Large Bipartite Networks: Implications for Precision Medicine

    PubMed Central

    Bhavnani, Suresh K.; Chen, Tianlong; Ayyaswamy, Archana; Visweswaran, Shyam; Bellala, Gowtham; Rohit, Divekar; Kevin E., Bassler

    2017-01-01

    A primary goal of precision medicine is to identify patient subgroups based on their characteristics (e.g., comorbidities or genes) with the goal of designing more targeted interventions. While network visualization methods such as Fruchterman-Reingold have been used to successfully identify such patient subgroups in small to medium sized data sets, they often fail to reveal comprehensible visual patterns in large and dense networks despite having significant clustering. We therefore developed an algorithm called ExplodeLayout, which exploits the existence of significant clusters in bipartite networks to automatically “explode” a traditional network layout with the goal of separating overlapping clusters, while at the same time preserving key network topological properties that are critical for the comprehension of patient subgroups. We demonstrate the utility of ExplodeLayout by visualizing a large dataset extracted from Medicare consisting of readmitted hip-fracture patients and their comorbidities, demonstrate its statistically significant improvement over a traditional layout algorithm, and discuss how the resulting network visualization enabled clinicians to infer mechanisms precipitating hospital readmission in specific patient subgroups. PMID:28815099

  2. Curvature-processing network in macaque visual cortex

    PubMed Central

    Yue, Xiaomin; Pourladian, Irene S.; Tootell, Roger B. H.; Ungerleider, Leslie G.

    2014-01-01

    Our visual environment abounds with curved features. Thus, the goal of understanding visual processing should include the processing of curved features. Using functional magnetic resonance imaging in behaving monkeys, we demonstrated a network of cortical areas selective for the processing of curved features. This network includes three distinct hierarchically organized regions within the ventral visual pathway: a posterior curvature-biased patch (PCP) located in the near-foveal representation of dorsal V4, a middle curvature-biased patch (MCP) located on the ventral lip of the posterior superior temporal sulcus (STS) in area TEO, and an anterior curvature-biased patch (ACP) located just below the STS in anterior area TE. Our results further indicate that the processing of curvature becomes increasingly complex from PCP to ACP. The proximity of the curvature-processing network to the well-known face-processing network suggests a possible functional link between them. PMID:25092328

  3. Salience network dynamics underlying successful resistance of temptation

    PubMed Central

    Nomi, Jason S; Calhoun, Vince D; Stelzel, Christine; Paschke, Lena M; Gaschler, Robert; Goschke, Thomas; Walter, Henrik; Uddin, Lucina Q

    2017-01-01

    Abstract Self-control and the ability to resist temptation are critical for successful completion of long-term goals. Contemporary models in cognitive neuroscience emphasize the primary role of prefrontal cognitive control networks in aligning behavior with such goals. Here, we use gaze pattern analysis and dynamic functional connectivity fMRI data to explore how individual differences in the ability to resist temptation are related to intrinsic brain dynamics of the cognitive control and salience networks. Behaviorally, individuals exhibit greater gaze distance from target location (e.g. higher distractibility) during presentation of tempting erotic images compared with neutral images. Individuals whose intrinsic dynamic functional connectivity patterns gravitate toward configurations in which salience detection systems are less strongly coupled with visual systems resist tempting distractors more effectively. The ability to resist tempting distractors was not significantly related to intrinsic dynamics of the cognitive control network. These results suggest that susceptibility to temptation is governed in part by individual differences in salience network dynamics and provide novel evidence for involvement of brain systems outside canonical cognitive control networks in contributing to individual differences in self-control. PMID:29048582

  4. Neural network modelling of the influence of channelopathies on reflex visual attention.

    PubMed

    Gravier, Alexandre; Quek, Chai; Duch, Włodzisław; Wahab, Abdul; Gravier-Rymaszewska, Joanna

    2016-02-01

    This paper introduces a model of Emergent Visual Attention in presence of calcium channelopathy (EVAC). By modelling channelopathy, EVAC constitutes an effort towards identifying the possible causes of autism. The network structure embodies the dual pathways model of cortical processing of visual input, with reflex attention as an emergent property of neural interactions. EVAC extends existing work by introducing attention shift in a larger-scale network and applying a phenomenological model of channelopathy. In presence of a distractor, the channelopathic network's rate of failure to shift attention is lower than the control network's, but overall, the control network exhibits a lower classification error rate. The simulation results also show differences in task-relative reaction times between control and channelopathic networks. The attention shift timings inferred from the model are consistent with studies of attention shift in autistic children.

  5. Hierarchical organization of brain functional networks during visual tasks.

    PubMed

    Zhuo, Zhao; Cai, Shi-Min; Fu, Zhong-Qian; Zhang, Jie

    2011-09-01

    The functional network of the brain is known to demonstrate modular structure over different hierarchical scales. In this paper, we systematically investigated the hierarchical modular organizations of the brain functional networks that are derived from the extent of phase synchronization among high-resolution EEG time series during a visual task. In particular, we compare the modular structure of the functional network from EEG channels with that of the anatomical parcellation of the brain cortex. Our results show that the modular architectures of brain functional networks correspond well to those from the anatomical structures over different levels of hierarchy. Most importantly, we find that the consistency between the modular structures of the functional network and the anatomical network becomes more pronounced in terms of vision, sensory, vision-temporal, motor cortices during the visual task, which implies that the strong modularity in these areas forms the functional basis for the visual task. The structure-function relationship further reveals that the phase synchronization of EEG time series in the same anatomical group is much stronger than that of EEG time series from different anatomical groups during the task and that the hierarchical organization of functional brain network may be a consequence of functional segmentation of the brain cortex.

  6. Incremental Support Vector Machine Framework for Visual Sensor Networks

    NASA Astrophysics Data System (ADS)

    Awad, Mariette; Jiang, Xianhua; Motai, Yuichi

    2006-12-01

    Motivated by the emerging requirements of surveillance networks, we present in this paper an incremental multiclassification support vector machine (SVM) technique as a new framework for action classification based on real-time multivideo collected by homogeneous sites. The technique is based on an adaptation of least square SVM (LS-SVM) formulation but extends beyond the static image-based learning of current SVM methodologies. In applying the technique, an initial supervised offline learning phase is followed by a visual behavior data acquisition and an online learning phase during which the cluster head performs an ensemble of model aggregations based on the sensor nodes inputs. The cluster head then selectively switches on designated sensor nodes for future incremental learning. Combining sensor data offers an improvement over single camera sensing especially when the latter has an occluded view of the target object. The optimization involved alleviates the burdens of power consumption and communication bandwidth requirements. The resulting misclassification error rate, the iterative error reduction rate of the proposed incremental learning, and the decision fusion technique prove its validity when applied to visual sensor networks. Furthermore, the enabled online learning allows an adaptive domain knowledge insertion and offers the advantage of reducing both the model training time and the information storage requirements of the overall system which makes it even more attractive for distributed sensor networks communication.

  7. VirtualPlant: A Software Platform to Support Systems Biology Research1[W][OA

    PubMed Central

    Katari, Manpreet S.; Nowicki, Steve D.; Aceituno, Felipe F.; Nero, Damion; Kelfer, Jonathan; Thompson, Lee Parnell; Cabello, Juan M.; Davidson, Rebecca S.; Goldberg, Arthur P.; Shasha, Dennis E.; Coruzzi, Gloria M.; Gutiérrez, Rodrigo A.

    2010-01-01

    Data generation is no longer the limiting factor in advancing biological research. In addition, data integration, analysis, and interpretation have become key bottlenecks and challenges that biologists conducting genomic research face daily. To enable biologists to derive testable hypotheses from the increasing amount of genomic data, we have developed the VirtualPlant software platform. VirtualPlant enables scientists to visualize, integrate, and analyze genomic data from a systems biology perspective. VirtualPlant integrates genome-wide data concerning the known and predicted relationships among genes, proteins, and molecules, as well as genome-scale experimental measurements. VirtualPlant also provides visualization techniques that render multivariate information in visual formats that facilitate the extraction of biological concepts. Importantly, VirtualPlant helps biologists who are not trained in computer science to mine lists of genes, microarray experiments, and gene networks to address questions in plant biology, such as: What are the molecular mechanisms by which internal or external perturbations affect processes controlling growth and development? We illustrate the use of VirtualPlant with three case studies, ranging from querying a gene of interest to the identification of gene networks and regulatory hubs that control seed development. Whereas the VirtualPlant software was developed to mine Arabidopsis (Arabidopsis thaliana) genomic data, its data structures, algorithms, and visualization tools are designed in a species-independent way. VirtualPlant is freely available at www.virtualplant.org. PMID:20007449

  8. A self-organizing model of perisaccadic visual receptive field dynamics in primate visual and oculomotor system.

    PubMed

    Mender, Bedeho M W; Stringer, Simon M

    2015-01-01

    We propose and examine a model for how perisaccadic visual receptive field dynamics, observed in a range of primate brain areas such as LIP, FEF, SC, V3, V3A, V2, and V1, may develop through a biologically plausible process of unsupervised visually guided learning. These dynamics are associated with remapping, which is the phenomenon where receptive fields anticipate the consequences of saccadic eye movements. We find that a neural network model using a local associative synaptic learning rule, when exposed to visual scenes in conjunction with saccades, can account for a range of associated phenomena. In particular, our model demonstrates predictive and pre-saccadic remapping, responsiveness shifts around the time of saccades, and remapping from multiple directions.

  9. A self-organizing model of perisaccadic visual receptive field dynamics in primate visual and oculomotor system

    PubMed Central

    Mender, Bedeho M. W.; Stringer, Simon M.

    2015-01-01

    We propose and examine a model for how perisaccadic visual receptive field dynamics, observed in a range of primate brain areas such as LIP, FEF, SC, V3, V3A, V2, and V1, may develop through a biologically plausible process of unsupervised visually guided learning. These dynamics are associated with remapping, which is the phenomenon where receptive fields anticipate the consequences of saccadic eye movements. We find that a neural network model using a local associative synaptic learning rule, when exposed to visual scenes in conjunction with saccades, can account for a range of associated phenomena. In particular, our model demonstrates predictive and pre-saccadic remapping, responsiveness shifts around the time of saccades, and remapping from multiple directions. PMID:25717301

  10. A hierarchy of timescales explains distinct effects of local inhibition of primary visual cortex and frontal eye fields

    PubMed Central

    Cocchi, Luca; Sale, Martin V; L Gollo, Leonardo; Bell, Peter T; Nguyen, Vinh T; Zalesky, Andrew; Breakspear, Michael; Mattingley, Jason B

    2016-01-01

    Within the primate visual system, areas at lower levels of the cortical hierarchy process basic visual features, whereas those at higher levels, such as the frontal eye fields (FEF), are thought to modulate sensory processes via feedback connections. Despite these functional exchanges during perception, there is little shared activity between early and late visual regions at rest. How interactions emerge between regions encompassing distinct levels of the visual hierarchy remains unknown. Here we combined neuroimaging, non-invasive cortical stimulation and computational modelling to characterize changes in functional interactions across widespread neural networks before and after local inhibition of primary visual cortex or FEF. We found that stimulation of early visual cortex selectively increased feedforward interactions with FEF and extrastriate visual areas, whereas identical stimulation of the FEF decreased feedback interactions with early visual areas. Computational modelling suggests that these opposing effects reflect a fast-slow timescale hierarchy from sensory to association areas. DOI: http://dx.doi.org/10.7554/eLife.15252.001 PMID:27596931

  11. A hierarchy of timescales explains distinct effects of local inhibition of primary visual cortex and frontal eye fields.

    PubMed

    Cocchi, Luca; Sale, Martin V; L Gollo, Leonardo; Bell, Peter T; Nguyen, Vinh T; Zalesky, Andrew; Breakspear, Michael; Mattingley, Jason B

    2016-09-06

    Within the primate visual system, areas at lower levels of the cortical hierarchy process basic visual features, whereas those at higher levels, such as the frontal eye fields (FEF), are thought to modulate sensory processes via feedback connections. Despite these functional exchanges during perception, there is little shared activity between early and late visual regions at rest. How interactions emerge between regions encompassing distinct levels of the visual hierarchy remains unknown. Here we combined neuroimaging, non-invasive cortical stimulation and computational modelling to characterize changes in functional interactions across widespread neural networks before and after local inhibition of primary visual cortex or FEF. We found that stimulation of early visual cortex selectively increased feedforward interactions with FEF and extrastriate visual areas, whereas identical stimulation of the FEF decreased feedback interactions with early visual areas. Computational modelling suggests that these opposing effects reflect a fast-slow timescale hierarchy from sensory to association areas.

  12. Development of a computational model on the neural activity patterns of a visual working memory in a hierarchical feedforward Network

    NASA Astrophysics Data System (ADS)

    An, Soyoung; Choi, Woochul; Paik, Se-Bum

    2015-11-01

    Understanding the mechanism of information processing in the human brain remains a unique challenge because the nonlinear interactions between the neurons in the network are extremely complex and because controlling every relevant parameter during an experiment is difficult. Therefore, a simulation using simplified computational models may be an effective approach. In the present study, we developed a general model of neural networks that can simulate nonlinear activity patterns in the hierarchical structure of a neural network system. To test our model, we first examined whether our simulation could match the previously-observed nonlinear features of neural activity patterns. Next, we performed a psychophysics experiment for a simple visual working memory task to evaluate whether the model could predict the performance of human subjects. Our studies show that the model is capable of reproducing the relationship between memory load and performance and may contribute, in part, to our understanding of how the structure of neural circuits can determine the nonlinear neural activity patterns in the human brain.

  13. Optical Histology: High-Resolution Visualization of Tissue Microvasculature

    NASA Astrophysics Data System (ADS)

    Moy, Austin Jing-Ming

    Mammalian tissue requires the delivery of nutrients, growth factors, and the exchange of oxygen and carbon dioxide gases to maintain normal function. These elements are delivered by the blood, which travels through the connected network of blood vessels, known as the vascular system. The vascular system consists of large feeder blood vessels (arteries and veins) that are connected to the small blood vessels (arterioles and venules), which in turn are connected to the capillaries that are directly connected to the tissue and facilitate gas exchange and nutrient delivery. These small blood vessels and capillaries make up an intricate but organized network of blood vessels that exist in all mammalian tissues known as the microvasculature and are very important in maintaining the health and proper function of mammalian tissue. Due to the importance of the microvasculature in tissue survival, disruption of the microvasculature typically leads to tissue dysfunction and tissue death. The most prevalent method to study the microvasculature is visualization. Immunohistochemistry (IHC) is the gold-standard method to visualize tissue microvasculature. IHC is very well-suited for highly detailed interrogation of the tissue microvasculature at the cellular level but is unwieldy and impractical for wide-field visualization of the tissue microvasculature. The objective my dissertation research was to develop a method to enable wide-field visualization of the microvasculature, while still retaining the high-resolution afforded by optical microscopy. My efforts led to the development of a technique dubbed "optical histology" that combines chemical and optical methods to enable high-resolution visualization of the microvasculature. The development of the technique first involved preliminary studies to quantify optical property changes in optically cleared tissues, followed by development and demonstration of the methodology. Using optical histology, I successfully obtained high resolution, depth sectioned images of the microvasculature in mouse brain and the coronary microvasculature in mouse heart. Future directions of optical histology include the potential to facilitate visualization of the entire microvascular structure of an organ as well as visualization of other tissue molecular markers of interest.

  14. Visualizing deep neural network by alternately image blurring and deblurring.

    PubMed

    Wang, Feng; Liu, Haijun; Cheng, Jian

    2018-01-01

    Visualization from trained deep neural networks has drawn massive public attention in recent. One of the visualization approaches is to train images maximizing the activation of specific neurons. However, directly maximizing the activation would lead to unrecognizable images, which cannot provide any meaningful information. In this paper, we introduce a simple but effective technique to constrain the optimization route of the visualization. By adding two totally inverse transformations, image blurring and deblurring, to the optimization procedure, recognizable images can be created. Our algorithm is good at extracting the details in the images, which are usually filtered by previous methods in the visualizations. Extensive experiments on AlexNet, VGGNet and GoogLeNet illustrate that we can better understand the neural networks utilizing the knowledge obtained by the visualization. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Network model of top-down influences on local gain and contextual interactions in visual cortex.

    PubMed

    Piëch, Valentin; Li, Wu; Reeke, George N; Gilbert, Charles D

    2013-10-22

    The visual system uses continuity as a cue for grouping oriented line segments that define object boundaries in complex visual scenes. Many studies support the idea that long-range intrinsic horizontal connections in early visual cortex contribute to this grouping. Top-down influences in primary visual cortex (V1) play an important role in the processes of contour integration and perceptual saliency, with contour-related responses being task dependent. This suggests an interaction between recurrent inputs to V1 and intrinsic connections within V1 that enables V1 neurons to respond differently under different conditions. We created a network model that simulates parametrically the control of local gain by hypothetical top-down modification of local recurrence. These local gain changes, as a consequence of network dynamics in our model, enable modulation of contextual interactions in a task-dependent manner. Our model displays contour-related facilitation of neuronal responses and differential foreground vs. background responses over the neuronal ensemble, accounting for the perceptual pop-out of salient contours. It quantitatively reproduces the results of single-unit recording experiments in V1, highlighting salient contours and replicating the time course of contextual influences. We show by means of phase-plane analysis that the model operates stably even in the presence of large inputs. Our model shows how a simple form of top-down modulation of the effective connectivity of intrinsic cortical connections among biophysically realistic neurons can account for some of the response changes seen in perceptual learning and task switching.

  16. Development of a Three Dimensional Wireless Sensor Network for Terrain-Climate Research in Remote Mountainous Environments

    NASA Astrophysics Data System (ADS)

    Kavanagh, K.; Davis, A.; Gessler, P.; Hess, H.; Holden, Z.; Link, T. E.; Newingham, B. A.; Smith, A. M.; Robinson, P.

    2011-12-01

    Developing sensor networks that are robust enough to perform in the world's remote regions is critical since these regions serve as important benchmarks compared to human-dominated areas. Paradoxically, the factors that make these remote, natural sites challenging for sensor networking are often what make them indispensable for climate change research. We aim to overcome these challenges by developing a three-dimensional sensor network arrayed across a topoclimatic gradient (1100-1800 meters) in a wilderness area in central Idaho. Development of this sensor array builds upon advances in sensing, networking, and power supply technologies coupled with experiences of the multidisciplinary investigators in conducting research in remote mountainous locations. The proposed gradient monitoring network will provide near real-time data from a three-dimensional (3-D) array of sensors measuring biophysical parameters used in ecosystem process models. The network will monitor atmospheric carbon dioxide concentration, humidity, air and soil temperature, soil water content, precipitation, incoming and outgoing shortwave and longwave radiation, snow depth, wind speed and direction, tree stem growth and leaf wetness at time intervals ranging from seconds to days. The long-term goal of this project is to realize a transformative integration of smart sensor networks adaptively communicating data in real-time to ultimately achieve a 3-D visualization of ecosystem processes within remote mountainous regions. Process models will be the interface between the visualization platforms and the sensor network. This will allow us to better predict how non-human dominated terrestrial and aquatic ecosystems function and respond to climate dynamics. Access to the data will be ensured as part of the Northwest Knowledge Network being developed at the University of Idaho, through ongoing Idaho NSF-funded cyber infrastructure initiatives, and existing data management systems funded by NSF, such as the CUAHSI Hydrologic Information System (HIS). These efforts will enhance cross-disciplinary understanding of natural and anthropogenic influences on ecosystem function and ultimately inform decision-making.

  17. Biocharts: a visual formalism for complex biological systems

    PubMed Central

    Kugler, Hillel; Larjo, Antti; Harel, David

    2010-01-01

    We address one of the central issues in devising languages, methods and tools for the modelling and analysis of complex biological systems, that of linking high-level (e.g. intercellular) information with lower-level (e.g. intracellular) information. Adequate ways of dealing with this issue are crucial for understanding biological networks and pathways, which typically contain huge amounts of data that continue to grow as our knowledge and understanding of a system increases. Trying to comprehend such data using the standard methods currently in use is often virtually impossible. We propose a two-tier compound visual language, which we call Biocharts, that is geared towards building fully executable models of biological systems. One of the main goals of our approach is to enable biologists to actively participate in the computational modelling effort, in a natural way. The high-level part of our language is a version of statecharts, which have been shown to be extremely successful in software and systems engineering. The statecharts can be combined with any appropriately well-defined language (preferably a diagrammatic one) for specifying the low-level dynamics of the pathways and networks. We illustrate the language and our general modelling approach using the well-studied process of bacterial chemotaxis. PMID:20022895

  18. Off-the-shelf Control of Data Analysis Software

    NASA Astrophysics Data System (ADS)

    Wampler, S.

    The Gemini Project must provide convenient access to data analysis facilities to a wide user community. The international nature of this community makes the selection of data analysis software particularly interesting, with staunch advocates of systems such as ADAM and IRAF among the users. Additionally, the continuing trends towards increased use of networked systems and distributed processing impose additional complexity. To meet these needs, the Gemini Project is proposing the novel approach of using low-cost, off-the-shelf software to abstract out both the control and distribution of data analysis from the functionality of the data analysis software. For example, the orthogonal nature of control versus function means that users might select analysis routines from both ADAM and IRAF as appropriate, distributing these routines across a network of machines. It is the belief of the Gemini Project that this approach results in a system that is highly flexible, maintainable, and inexpensive to develop. The Khoros visualization system is presented as an example of control software that is currently available for providing the control and distribution within a data analysis system. The visual programming environment provided with Khoros is also discussed as a means to providing convenient access to this control.

  19. Feasibility Study of a Vision-Based Landing System for Unmanned Fixed-Wing Aircraft

    DTIC Science & Technology

    2017-06-01

    International Journal of Computer Science and Network Security 7 no. 3: 112–117. Accessed April 7, 2017. http://www.sciencedirect.com/science/ article /pii...the feasibility of applying computer vision techniques and visual feedback in the control loop for an autonomous system. This thesis examines the...integration into an autonomous aircraft control system. 14. SUBJECT TERMS autonomous systems, auto-land, computer vision, image processing

  20. Distributed Estimation, Coding, and Scheduling in Wireless Visual Sensor Networks

    ERIC Educational Resources Information Center

    Yu, Chao

    2013-01-01

    In this thesis, we consider estimation, coding, and sensor scheduling for energy efficient operation of wireless visual sensor networks (VSN), which consist of battery-powered wireless sensors with sensing (imaging), computation, and communication capabilities. The competing requirements for applications of these wireless sensor networks (WSN)…

  1. Deep Neural Networks Rival the Representation of Primate IT Cortex for Core Visual Object Recognition

    PubMed Central

    Cadieu, Charles F.; Hong, Ha; Yamins, Daniel L. K.; Pinto, Nicolas; Ardila, Diego; Solomon, Ethan A.; Majaj, Najib J.; DiCarlo, James J.

    2014-01-01

    The primate visual system achieves remarkable visual object recognition performance even in brief presentations, and under changes to object exemplar, geometric transformations, and background variation (a.k.a. core visual object recognition). This remarkable performance is mediated by the representation formed in inferior temporal (IT) cortex. In parallel, recent advances in machine learning have led to ever higher performing models of object recognition using artificial deep neural networks (DNNs). It remains unclear, however, whether the representational performance of DNNs rivals that of the brain. To accurately produce such a comparison, a major difficulty has been a unifying metric that accounts for experimental limitations, such as the amount of noise, the number of neural recording sites, and the number of trials, and computational limitations, such as the complexity of the decoding classifier and the number of classifier training examples. In this work, we perform a direct comparison that corrects for these experimental limitations and computational considerations. As part of our methodology, we propose an extension of “kernel analysis” that measures the generalization accuracy as a function of representational complexity. Our evaluations show that, unlike previous bio-inspired models, the latest DNNs rival the representational performance of IT cortex on this visual object recognition task. Furthermore, we show that models that perform well on measures of representational performance also perform well on measures of representational similarity to IT, and on measures of predicting individual IT multi-unit responses. Whether these DNNs rely on computational mechanisms similar to the primate visual system is yet to be determined, but, unlike all previous bio-inspired models, that possibility cannot be ruled out merely on representational performance grounds. PMID:25521294

  2. Reading in Two Writing Systems: Accommodation and Assimilation of the Brain's Reading Network

    ERIC Educational Resources Information Center

    Perfetti, Charles A.; Liu, Ying; Fiez, Julie; Nelson, Jessica; Bolger, Donald J.; Tan, Li-Hai

    2007-01-01

    Bilingual reading can require more than knowing two languages. Learners must acquire also the writing conventions of their second language, which can differ in its deep mapping principles (writing system) and its visual configurations (script). We review ERP (event-related potential) and fMRI studies of both Chinese-English bilingualism and…

  3. Atlas of Cancer Signalling Network: a systems biology resource for integrative analysis of cancer data with Google Maps

    PubMed Central

    Kuperstein, I; Bonnet, E; Nguyen, H-A; Cohen, D; Viara, E; Grieco, L; Fourquet, S; Calzone, L; Russo, C; Kondratova, M; Dutreix, M; Barillot, E; Zinovyev, A

    2015-01-01

    Cancerogenesis is driven by mutations leading to aberrant functioning of a complex network of molecular interactions and simultaneously affecting multiple cellular functions. Therefore, the successful application of bioinformatics and systems biology methods for analysis of high-throughput data in cancer research heavily depends on availability of global and detailed reconstructions of signalling networks amenable for computational analysis. We present here the Atlas of Cancer Signalling Network (ACSN), an interactive and comprehensive map of molecular mechanisms implicated in cancer. The resource includes tools for map navigation, visualization and analysis of molecular data in the context of signalling network maps. Constructing and updating ACSN involves careful manual curation of molecular biology literature and participation of experts in the corresponding fields. The cancer-oriented content of ACSN is completely original and covers major mechanisms involved in cancer progression, including DNA repair, cell survival, apoptosis, cell cycle, EMT and cell motility. Cell signalling mechanisms are depicted in detail, together creating a seamless ‘geographic-like' map of molecular interactions frequently deregulated in cancer. The map is browsable using NaviCell web interface using the Google Maps engine and semantic zooming principle. The associated web-blog provides a forum for commenting and curating the ACSN content. ACSN allows uploading heterogeneous omics data from users on top of the maps for visualization and performing functional analyses. We suggest several scenarios for ACSN application in cancer research, particularly for visualizing high-throughput data, starting from small interfering RNA-based screening results or mutation frequencies to innovative ways of exploring transcriptomes and phosphoproteomes. Integration and analysis of these data in the context of ACSN may help interpret their biological significance and formulate mechanistic hypotheses. ACSN may also support patient stratification, prediction of treatment response and resistance to cancer drugs, as well as design of novel treatment strategies. PMID:26192618

  4. Ventral and dorsal streams processing visual motion perception (FDG-PET study)

    PubMed Central

    2012-01-01

    Background Earlier functional imaging studies on visually induced self-motion perception (vection) disclosed a bilateral network of activations within primary and secondary visual cortex areas which was combined with signal decreases, i.e., deactivations, in multisensory vestibular cortex areas. This finding led to the concept of a reciprocal inhibitory interaction between the visual and vestibular systems. In order to define areas involved in special aspects of self-motion perception such as intensity and duration of the perceived circular vection (CV) or the amount of head tilt, correlation analyses of the regional cerebral glucose metabolism, rCGM (measured by fluorodeoxyglucose positron-emission tomography, FDG-PET) and these perceptual covariates were performed in 14 healthy volunteers. For analyses of the visual-vestibular interaction, the CV data were compared to a random dot motion stimulation condition (not inducing vection) and a control group at rest (no stimulation at all). Results Group subtraction analyses showed that the visual-vestibular interaction was modified during CV, i.e., the activations within the cerebellar vermis and parieto-occipital areas were enhanced. The correlation analysis between the rCGM and the intensity of visually induced vection, experienced as body tilt, showed a relationship for areas of the multisensory vestibular cortical network (inferior parietal lobule bilaterally, anterior cingulate gyrus), the medial parieto-occipital cortex, the frontal eye fields and the cerebellar vermis. The “earlier” multisensory vestibular areas like the parieto-insular vestibular cortex and the superior temporal gyrus did not appear in the latter analysis. The duration of perceived vection after stimulus stop was positively correlated with rCGM in medial temporal lobe areas bilaterally, which included the (para-)hippocampus, known to be involved in various aspects of memory processing. The amount of head tilt was found to be positively correlated with the rCGM of bilateral basal ganglia regions responsible for the control of motor function of the head. Conclusions Our data gave further insights into subfunctions within the complex cortical network involved in the processing of visual-vestibular interaction during CV. Specific areas of this cortical network could be attributed to the ventral stream (“what” pathway) responsible for the duration after stimulus stop and to the dorsal stream (“where/how” pathway) responsible for intensity aspects. PMID:22800430

  5. Network representations of immune system complexity

    PubMed Central

    Subramanian, Naeha; Torabi-Parizi, Parizad; Gottschalk, Rachel A.; Germain, Ronald N.; Dutta, Bhaskar

    2015-01-01

    The mammalian immune system is a dynamic multi-scale system composed of a hierarchically organized set of molecular, cellular and organismal networks that act in concert to promote effective host defense. These networks range from those involving gene regulatory and protein-protein interactions underlying intracellular signaling pathways and single cell responses to increasingly complex networks of in vivo cellular interaction, positioning and migration that determine the overall immune response of an organism. Immunity is thus not the product of simple signaling events but rather non-linear behaviors arising from dynamic, feedback-regulated interactions among many components. One of the major goals of systems immunology is to quantitatively measure these complex multi-scale spatial and temporal interactions, permitting development of computational models that can be used to predict responses to perturbation. Recent technological advances permit collection of comprehensive datasets at multiple molecular and cellular levels while advances in network biology support representation of the relationships of components at each level as physical or functional interaction networks. The latter facilitate effective visualization of patterns and recognition of emergent properties arising from the many interactions of genes, molecules, and cells of the immune system. We illustrate the power of integrating ‘omics’ and network modeling approaches for unbiased reconstruction of signaling and transcriptional networks with a focus on applications involving the innate immune system. We further discuss future possibilities for reconstruction of increasingly complex cellular and organism-level networks and development of sophisticated computational tools for prediction of emergent immune behavior arising from the concerted action of these networks. PMID:25625853

  6. Kalai-Smorodinsky bargaining solution for optimal resource allocation over wireless DS-CDMA visual sensor networks

    NASA Astrophysics Data System (ADS)

    Pandremmenou, Katerina; Kondi, Lisimachos P.; Parsopoulos, Konstantinos E.

    2012-01-01

    Surveillance applications usually require high levels of video quality, resulting in high power consumption. The existence of a well-behaved scheme to balance video quality and power consumption is crucial for the system's performance. In the present work, we adopt the game-theoretic approach of Kalai-Smorodinsky Bargaining Solution (KSBS) to deal with the problem of optimal resource allocation in a multi-node wireless visual sensor network (VSN). In our setting, the Direct Sequence Code Division Multiple Access (DS-CDMA) method is used for channel access, while a cross-layer optimization design, which employs a central processing server, accounts for the overall system efficacy through all network layers. The task assigned to the central server is the communication with the nodes and the joint determination of their transmission parameters. The KSBS is applied to non-convex utility spaces, efficiently distributing the source coding rate, channel coding rate and transmission powers among the nodes. In the underlying model, the transmission powers assume continuous values, whereas the source and channel coding rates can take only discrete values. Experimental results are reported and discussed to demonstrate the merits of KSBS over competing policies.

  7. VIDAC; A New Technology for Increasing the Effectiveness of Television Distribution Networks: Report on a Feasibility Study of a Central Library "Integrated Media" Satellite Delivery System.

    ERIC Educational Resources Information Center

    Diambra, Henry M.; And Others

    VIDAC (Video Audio Compressed), a new technology based upon non-real-time transmission of audiovisual information via conventional television systems, has been invented by the Westinghouse Electric Corporation. This system permits time compression, during storage and transmission of the audio component of a still visual-narrative audio…

  8. Advanced Lighting Controls for Reducing Energy use and Cost in DoD Installations

    DTIC Science & Technology

    2013-05-01

    OccuSwitch Wireless is a room-based lighting control system employing dimmable light sources, occupancy and daylight sensors , wireless interconnection...combination of wireless and wired control solution for building-wide networked system that maximizes the use of daylight while improving visual...architecture of Hybrid ILDC. Architecture: The system features wireless connectivity among sensors and actuators within a zone and exploits wired

  9. Five-dimensional ultrasound system for soft tissue visualization.

    PubMed

    Deshmukh, Nishikant P; Caban, Jesus J; Taylor, Russell H; Hager, Gregory D; Boctor, Emad M

    2015-12-01

    A five-dimensional ultrasound (US) system is proposed as a real-time pipeline involving fusion of 3D B-mode data with the 3D ultrasound elastography (USE) data as well as visualization of these fused data and a real-time update capability over time for each consecutive scan. 3D B-mode data assist in visualizing the anatomy of the target organ, and 3D elastography data adds strain information. We investigate the feasibility of such a system and show that an end-to-end real-time system, from acquisition to visualization, can be developed. We present a system that consists of (a) a real-time 3D elastography algorithm based on a normalized cross-correlation (NCC) computation on a GPU; (b) real-time 3D B-mode acquisition and network transfer; (c) scan conversion of 3D elastography and B-mode volumes (if acquired by 4D wobbler probe); and (d) visualization software that fuses, visualizes, and updates 3D B-mode and 3D elastography data in real time. We achieved a speed improvement of 4.45-fold for the threaded version of the NCC-based 3D USE versus the non-threaded version. The maximum speed was 79 volumes/s for 3D scan conversion. In a phantom, we validated the dimensions of a 2.2-cm-diameter sphere scan-converted to B-mode volume. Also, we validated the 5D US system visualization transfer function and detected 1- and 2-cm spherical objects (phantom lesion). Finally, we applied the system to a phantom consisting of three lesions to delineate the lesions from the surrounding background regions of the phantom. A 5D US system is achievable with real-time performance. We can distinguish between hard and soft areas in a phantom using the transfer functions.

  10. Multimission Telemetry Visualization (MTV) system: A mission applications project from JPL's Multimedia Communications Laboratory

    NASA Technical Reports Server (NTRS)

    Koeberlein, Ernest, III; Pender, Shaw Exum

    1994-01-01

    This paper describes the Multimission Telemetry Visualization (MTV) data acquisition/distribution system. MTV was developed by JPL's Multimedia Communications Laboratory (MCL) and designed to process and display digital, real-time, science and engineering data from JPL's Mission Control Center. The MTV system can be accessed using UNIX workstations and PC's over common datacom and telecom networks from worldwide locations. It is designed to lower data distribution costs while increasing data analysis functionality by integrating low-cost, off-the-shelf desktop hardware and software. MTV is expected to significantly lower the cost of real-time data display, processing, distribution, and allow for greater spacecraft safety and mission data access.

  11. ACTIVIS: Visual Exploration of Industry-Scale Deep Neural Network Models.

    PubMed

    Kahng, Minsuk; Andrews, Pierre Y; Kalro, Aditya; Polo Chau, Duen Horng

    2017-08-30

    While deep learning models have achieved state-of-the-art accuracies for many prediction tasks, understanding these models remains a challenge. Despite the recent interest in developing visual tools to help users interpret deep learning models, the complexity and wide variety of models deployed in industry, and the large-scale datasets that they used, pose unique design challenges that are inadequately addressed by existing work. Through participatory design sessions with over 15 researchers and engineers at Facebook, we have developed, deployed, and iteratively improved ACTIVIS, an interactive visualization system for interpreting large-scale deep learning models and results. By tightly integrating multiple coordinated views, such as a computation graph overview of the model architecture, and a neuron activation view for pattern discovery and comparison, users can explore complex deep neural network models at both the instance- and subset-level. ACTIVIS has been deployed on Facebook's machine learning platform. We present case studies with Facebook researchers and engineers, and usage scenarios of how ACTIVIS may work with different models.

  12. JuxtaView - A tool for interactive visualization of large imagery on scalable tiled displays

    USGS Publications Warehouse

    Krishnaprasad, N.K.; Vishwanath, V.; Venkataraman, S.; Rao, A.G.; Renambot, L.; Leigh, J.; Johnson, A.E.; Davis, B.

    2004-01-01

    JuxtaView is a cluster-based application for viewing ultra-high-resolution images on scalable tiled displays. We present in JuxtaView, a new parallel computing and distributed memory approach for out-of-core montage visualization, using LambdaRAM, a software-based network-level cache system. The ultimate goal of JuxtaView is to enable a user to interactively roam through potentially terabytes of distributed, spatially referenced image data such as those from electron microscopes, satellites and aerial photographs. In working towards this goal, we describe our first prototype implemented over a local area network, where the image is distributed using LambdaRAM, on the memory of all nodes of a PC cluster driving a tiled display wall. Aggressive pre-fetching schemes employed by LambdaRAM help to reduce latency involved in remote memory access. We compare LambdaRAM with a more traditional memory-mapped file approach for out-of-core visualization. ?? 2004 IEEE.

  13. Improving resolution of dynamic communities in human brain networks through targeted node removal

    PubMed Central

    Turner, Benjamin O.; Miller, Michael B.; Carlson, Jean M.

    2017-01-01

    Current approaches to dynamic community detection in complex networks can fail to identify multi-scale community structure, or to resolve key features of community dynamics. We propose a targeted node removal technique to improve the resolution of community detection. Using synthetic oscillator networks with well-defined “ground truth” communities, we quantify the community detection performance of a common modularity maximization algorithm. We show that the performance of the algorithm on communities of a given size deteriorates when these communities are embedded in multi-scale networks with communities of different sizes, compared to the performance in a single-scale network. We demonstrate that targeted node removal during community detection improves performance on multi-scale networks, particularly when removing the most functionally cohesive nodes. Applying this approach to network neuroscience, we compare dynamic functional brain networks derived from fMRI data taken during both repetitive single-task and varied multi-task experiments. After the removal of regions in visual cortex, the most coherent functional brain area during the tasks, community detection is better able to resolve known functional brain systems into communities. In addition, node removal enables the algorithm to distinguish clear differences in brain network dynamics between these experiments, revealing task-switching behavior that was not identified with the visual regions present in the network. These results indicate that targeted node removal can improve spatial and temporal resolution in community detection, and they demonstrate a promising approach for comparison of network dynamics between neuroscientific data sets with different resolution parameters. PMID:29261662

  14. A computational study of whole-brain connectivity in resting state and task fMRI

    PubMed Central

    Goparaju, Balaji; Rana, Kunjan D.; Calabro, Finnegan J.; Vaina, Lucia Maria

    2014-01-01

    Background We compared the functional brain connectivity produced during resting-state in which subjects were not actively engaged in a task with that produced while they actively performed a visual motion task (task-state). Material/Methods In this paper we employed graph-theoretical measures and network statistics in novel ways to compare, in the same group of human subjects, functional brain connectivity during resting-state fMRI with brain connectivity during performance of a high level visual task. We performed a whole-brain connectivity analysis to compare network statistics in resting and task states among anatomically defined Brodmann areas to investigate how brain networks spanning the cortex changed when subjects were engaged in task performance. Results In the resting state, we found strong connectivity among the posterior cingulate cortex (PCC), precuneus, medial prefrontal cortex (MPFC), lateral parietal cortex, and hippocampal formation, consistent with previous reports of the default mode network (DMN). The connections among these areas were strengthened while subjects actively performed an event-related visual motion task, indicating a continued and strong engagement of the DMN during task processing. Regional measures such as degree (number of connections) and betweenness centrality (number of shortest paths), showed that task performance induces stronger inter-regional connections, leading to a denser processing network, but that this does not imply a more efficient system as shown by the integration measures such as path length and global efficiency, and from global measures such as small-worldness. Conclusions In spite of the maintenance of connectivity and the “hub-like” behavior of areas, our results suggest that the network paths may be rerouted when performing the task condition. PMID:24947491

  15. Real-time optimizations for integrated smart network camera

    NASA Astrophysics Data System (ADS)

    Desurmont, Xavier; Lienard, Bruno; Meessen, Jerome; Delaigle, Jean-Francois

    2005-02-01

    We present an integrated real-time smart network camera. This system is composed of an image sensor, an embedded PC based electronic card for image processing and some network capabilities. The application detects events of interest in visual scenes, highlights alarms and computes statistics. The system also produces meta-data information that could be shared between other cameras in a network. We describe the requirements of such a system and then show how the design of the system is optimized to process and compress video in real-time. Indeed, typical video-surveillance algorithms as background differencing, tracking and event detection should be highly optimized and simplified to be used in this hardware. To have a good adequation between hardware and software in this light embedded system, the software management is written on top of the java based middle-ware specification established by the OSGi alliance. We can integrate easily software and hardware in complex environments thanks to the Java Real-Time specification for the virtual machine and some network and service oriented java specifications (like RMI and Jini). Finally, we will report some outcomes and typical case studies of such a camera like counter-flow detection.

  16. Retinotopic patterns of functional connectivity between V1 and large-scale brain networks during resting fixation

    PubMed Central

    Griffis, Joseph C.; Elkhetali, Abdurahman S.; Burge, Wesley K.; Chen, Richard H.; Bowman, Anthony D.; Szaflarski, Jerzy P.; Visscher, Kristina M.

    2016-01-01

    Psychophysical and neurobiological evidence suggests that central and peripheral vision are specialized for different functions. This specialization of function might be expected to lead to differences in the large-scale functional interactions of early cortical areas that represent central and peripheral visual space. Here, we characterize differences in whole-brain functional connectivity among sectors in primary visual cortex (V1) corresponding to central, near-peripheral, and far-peripheral vision during resting fixation. Importantly, our analyses reveal that eccentricity sectors in V1 have different functional connectivity with non-visual areas associated with large-scale brain networks. Regions associated with the fronto-parietal control network are most strongly connected with central sectors of V1, regions associated with the cingulo-opercular control network are most strongly connected with near-peripheral sectors of V1, and regions associated with the default mode and auditory networks are most strongly connected with far-peripheral sectors of V1. Additional analyses suggest that similar patterns are present during eyes-closed rest. These results suggest that different types of visual information may be prioritized by large-scale brain networks with distinct functional profiles, and provide insights into how the small-scale functional specialization within early visual regions such as V1 relates to the large-scale organization of functionally distinct whole-brain networks. PMID:27554527

  17. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Springmeyer, R R; Brugger, E; Cook, R

    The Data group provides data analysis and visualization support to its customers. This consists primarily of the development and support of VisIt, a data analysis and visualization tool. Support ranges from answering questions about the tool, providing classes on how to use the tool, and performing data analysis and visualization for customers. The Information Management and Graphics Group supports and develops tools that enhance our ability to access, display, and understand large, complex data sets. Activities include applying visualization software for large scale data exploration; running video production labs on two networks; supporting graphics libraries and tools for end users;more » maintaining PowerWalls and assorted other displays; and developing software for searching and managing scientific data. Researchers in the Center for Applied Scientific Computing (CASC) work on various projects including the development of visualization techniques for large scale data exploration that are funded by the ASC program, among others. The researchers also have LDRD projects and collaborations with other lab researchers, academia, and industry. The IMG group is located in the Terascale Simulation Facility, home to Dawn, Atlas, BGL, and others, which includes both classified and unclassified visualization theaters, a visualization computer floor and deployment workshop, and video production labs. We continued to provide the traditional graphics group consulting and video production support. We maintained five PowerWalls and many other displays. We deployed a 576-node Opteron/IB cluster with 72 TB of memory providing a visualization production server on our classified network. We continue to support a 128-node Opteron/IB cluster providing a visualization production server for our unclassified systems and an older 256-node Opteron/IB cluster for the classified systems, as well as several smaller clusters to drive the PowerWalls. The visualization production systems includes NFS servers to provide dedicated storage for data analysis and visualization. The ASC projects have delivered new versions of visualization and scientific data management tools to end users and continue to refine them. VisIt had 4 releases during the past year, ending with VisIt 2.0. We released version 2.4 of Hopper, a Java application for managing and transferring files. This release included a graphical disk usage view which works on all types of connections and an aggregated copy feature for quickly transferring massive datasets quickly and efficiently to HPSS. We continue to use and develop Blockbuster and Telepath. Both the VisIt and IMG teams were engaged in a variety of movie production efforts during the past year in addition to the development tasks.« less

  18. Artificial neural network does better spatiotemporal compressive sampling

    NASA Astrophysics Data System (ADS)

    Lee, Soo-Young; Hsu, Charles; Szu, Harold

    2012-06-01

    Spatiotemporal sparseness is generated naturally by human visual system based on artificial neural network modeling of associative memory. Sparseness means nothing more and nothing less than the compressive sensing achieves merely the information concentration. To concentrate the information, one uses the spatial correlation or spatial FFT or DWT or the best of all adaptive wavelet transform (cf. NUS, Shen Shawei). However, higher dimensional spatiotemporal information concentration, the mathematics can not do as flexible as a living human sensory system. The reason is obviously for survival reasons. The rest of the story is given in the paper.

  19. Real-time distributed video coding for 1K-pixel visual sensor networks

    NASA Astrophysics Data System (ADS)

    Hanca, Jan; Deligiannis, Nikos; Munteanu, Adrian

    2016-07-01

    Many applications in visual sensor networks (VSNs) demand the low-cost wireless transmission of video data. In this context, distributed video coding (DVC) has proven its potential to achieve state-of-the-art compression performance while maintaining low computational complexity of the encoder. Despite their proven capabilities, current DVC solutions overlook hardware constraints, and this renders them unsuitable for practical implementations. This paper introduces a DVC architecture that offers highly efficient wireless communication in real-world VSNs. The design takes into account the severe computational and memory constraints imposed by practical implementations on low-resolution visual sensors. We study performance-complexity trade-offs for feedback-channel removal, propose learning-based techniques for rate allocation, and investigate various simplifications of side information generation yielding real-time decoding. The proposed system is evaluated against H.264/AVC intra, Motion-JPEG, and our previously designed DVC prototype for low-resolution visual sensors. Extensive experimental results on various data show significant improvements in multiple configurations. The proposed encoder achieves real-time performance on a 1k-pixel visual sensor mote. Real-time decoding is performed on a Raspberry Pi single-board computer or a low-end notebook PC. To the best of our knowledge, the proposed codec is the first practical DVC deployment on low-resolution VSNs.

  20. Semantic Visualization of Wireless Sensor Networks for Elderly Monitoring

    NASA Astrophysics Data System (ADS)

    Stocklöw, Carsten; Kamieth, Felix

    In the area of Ambient Intelligence, Wireless Sensor Networks are commonly used for user monitoring purposes like health monitoring and user localization. Existing work on visualization of wireless sensor networks focuses mainly on displaying individual nodes and logical, graph-based topologies. This way, the relation to the real-world deployment is lost. This paper presents a novel approach for visualization of wireless sensor networks and interaction with complex services on the nodes. The environment is realized as a 3D model, and multiple nodes, that are worn by a single individual, are grouped together to allow an intuitive interface for end users. We describe application examples and show that our approach allows easier access to network information and functionality by comparing it with existing solutions.

  1. An Efficient and Versatile System for Visualization and Genetic Modification of Dopaminergic Neurons in Transgenic Mice

    PubMed Central

    Kramer, Edgar R.

    2015-01-01

    Background & Aims The brain dopaminergic (DA) system is involved in fine tuning many behaviors and several human diseases are associated with pathological alterations of the DA system such as Parkinson’s disease (PD) and drug addiction. Because of its complex network integration, detailed analyses of physiological and pathophysiological conditions are only possible in a whole organism with a sophisticated tool box for visualization and functional modification. Methods & Results Here, we have generated transgenic mice expressing the tetracycline-regulated transactivator (tTA) or the reverse tetracycline-regulated transactivator (rtTA) under control of the tyrosine hydroxylase (TH) promoter, TH-tTA (tet-OFF) and TH-rtTA (tet-ON) mice, to visualize and genetically modify DA neurons. We show their tight regulation and efficient use to overexpress proteins under the control of tet-responsive elements or to delete genes of interest with tet-responsive Cre. In combination with mice encoding tet-responsive luciferase, we visualized the DA system in living mice progressively over time. Conclusion These experiments establish TH-tTA and TH-rtTA mice as a powerful tool to generate and monitor mouse models for DA system diseases. PMID:26291828

  2. Visual agnosia and focal brain injury.

    PubMed

    Martinaud, O

    Visual agnosia encompasses all disorders of visual recognition within a selective visual modality not due to an impairment of elementary visual processing or other cognitive deficit. Based on a sequential dichotomy between the perceptual and memory systems, two different categories of visual object agnosia are usually considered: 'apperceptive agnosia' and 'associative agnosia'. Impaired visual recognition within a single category of stimuli is also reported in: (i) visual object agnosia of the ventral pathway, such as prosopagnosia (for faces), pure alexia (for words), or topographagnosia (for landmarks); (ii) visual spatial agnosia of the dorsal pathway, such as cerebral akinetopsia (for movement), or orientation agnosia (for the placement of objects in space). Focal brain injuries provide a unique opportunity to better understand regional brain function, particularly with the use of effective statistical approaches such as voxel-based lesion-symptom mapping (VLSM). The aim of the present work was twofold: (i) to review the various agnosia categories according to the traditional visual dual-pathway model; and (ii) to better assess the anatomical network underlying visual recognition through lesion-mapping studies correlating neuroanatomical and clinical outcomes. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  3. The Shale Hills Sensorium for Embedded Sensors, Simulation, & Visualization: A Prototype for Land-Vegetation-Atmosphere Interactions

    NASA Astrophysics Data System (ADS)

    Duffy, C.

    2008-12-01

    The future of environmental observing systems will utilize embedded sensor networks with continuous real- time measurement of hydrologic, atmospheric, biogeochemical, and ecological variables across diverse terrestrial environments. Embedded environmental sensors, benefitting from advances in information sciences, networking technology, materials science, computing capacity, and data synthesis methods, are undergoing revolutionary change. It is now possible to field spatially-distributed, multi-node sensor networks that provide density and spatial coverage previously accessible only via numerical simulation. At the same time, computational tools are advancing rapidly to the point where it is now possible to simulate the physical processes controlling individual parcels of water and solutes through the complete terrestrial water cycle. Our goal for the Penn State Critical Zone Observatory is to apply environmental sensor arrays, integrated hydrologic models, and state-of-the-art visualization deployed and coordinated at a testbed within the Penn State Experimental Forest. The Shale Hills Hydro_Sensorium prototype proposed here is designed to observe land-atmosphere interactions in four-dimensional (space and time). The term Hydro_Sensorium implies the totality of physical sensors, models and visualization tools that allow us to perceive the detailed space and time complexities of the water and energy cycle for a watershed or river basin for all physical states and fluxes (groundwater, soil moisture, temperature, streamflow, latent heat, snowmelt, chemistry, isotopes etc.). This research will ultimately catalyze the study of complex interactions between the land surface, subsurface, biological and atmospheric systems over a broad range of scales. The sensor array would be real-time and fully controllable by remote users for "computational steering" and data fusion. Presently fully-coupled physical models are being developed that link the atmosphere-land-vegetation-subsurface system into a fully-coupled distributed system. During the last 5 years the Penn State Integrated Hydrologic Modeling System has been under development as an open-source community modeling project funded by NSF EAR/GEO and NSF CBET/ENG. PIHM represents a strategy for the formulation and solution of fully-coupled process equations at the watershed and river basin scales, and includes a tightly coupled GIS tool for data handling, domain decomposition, optimal unstructured grid generation, and model parameterization. The sensor and simulation system has the following elements: 1) extensive, spatially-distributed, non- invasive, smart sensor networks to gather massive geologic, hydrologic, and geochemical data; 2) stochastic information fusion methods; 3) spatially-explicit multiphysics models/solutions of the land-vegetation- atmosphere system; and 4) asynchronous, parallel/distributed, adaptive algorithms for rapidly simulating the states of a basin at high resolution, 5) signal processing tools for data mining and parameter estimation, and 6) visualization tools. The prototype proposed sensor array and simulation system proposed here will offer a coherent new approach to environmental predictions with a fully integrated observing system design. We expect that the Shale Hills Hydro_Sensorium may provide the needed synthesis of information and conceptualization necessary to advance predictive understanding in complex hydrologic systems.

  4. Distributed Cognition on the road: Using EAST to explore future road transportation systems.

    PubMed

    Banks, Victoria A; Stanton, Neville A; Burnett, Gary; Hermawati, Setia

    2018-04-01

    Connected and Autonomous Vehicles (CAV) are set to revolutionise the way in which we use our transportation system. However, we do not fully understand how the integration of wireless and autonomous technology into the road transportation network affects overall network dynamism. This paper uses the theoretical principles underlying Distributed Cognition to explore the dependencies and interdependencies that exist between system agents located within the road environment, traffic management centres and other external agencies in both non-connected and connected transportation systems. This represents a significant step forward in modelling complex sociotechnical systems as it shows that the principles underlying Distributed Cognition can be applied to macro-level systems using the visual representations afforded by the Event Analysis of Systemic Teamwork (EAST) method. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. A robust low-rate coding scheme for packet video

    NASA Technical Reports Server (NTRS)

    Chen, Y. C.; Sayood, Khalid; Nelson, D. J.; Arikan, E. (Editor)

    1991-01-01

    Due to the rapidly evolving field of image processing and networking, video information promises to be an important part of telecommunication systems. Although up to now video transmission has been transported mainly over circuit-switched networks, it is likely that packet-switched networks will dominate the communication world in the near future. Asynchronous transfer mode (ATM) techniques in broadband-ISDN can provide a flexible, independent and high performance environment for video communication. For this paper, the network simulator was used only as a channel in this simulation. Mixture blocking coding with progressive transmission (MBCPT) has been investigated for use over packet networks and has been found to provide high compression rate with good visual performance, robustness to packet loss, tractable integration with network mechanics and simplicity in parallel implementation.

  6. A lightning strike to the head causing a visual cortex defect with simple and complex visual hallucinations

    PubMed Central

    Kleiter, Ingo; Luerding, Ralf; Diendorfer, Gerhard; Rek, Helga; Bogdahn, Ulrich; Schalke, Berthold

    2007-01-01

    The case of a 23‐year‐old mountaineer who was hit by a lightning strike to the occiput causing a large central visual field defect and bilateral tympanic membrane ruptures is described. Owing to extreme agitation, the patient was set to a drug‐induced coma for 3 days. After extubation, she experienced simple and complex visual hallucinations for several days, but otherwise recovered largely. Neuropsychological tests revealed deficits in fast visual detection tasks and non‐verbal learning, and indicated a right temporal lobe dysfunction, consistent with a right temporal focus on electroencephalography. Four months after the accident, she developed a psychological reaction consisting of nightmares with reappearance of the complex visual hallucinations and a depressive syndrome. Using the European Cooperation for Lightning Detection network, a meteorological system for lightning surveillance, the exact geographical location and nature of the lightning flash were retrospectively retraced. PMID:17369595

  7. A lightning strike to the head causing a visual cortex defect with simple and complex visual hallucinations

    PubMed Central

    Kleiter, Ingo; Luerding, Ralf; Diendorfer, Gerhard; Rek, Helga; Bogdahn, Ulrich; Schalke, Berthold

    2009-01-01

    The case of a 23-year-old mountaineer who was hit by a lightning strike to the occiput causing a large central visual field defect and bilateral tympanic membrane ruptures is described. Owing to extreme agitation, the patient was sent into a drug-induced coma for 3 days. After extubation, she experienced simple and complex visual hallucinations for several days, but otherwise largely recovered. Neuropsychological tests revealed deficits in fast visual detection tasks and non-verbal learning and indicated a right temporal lobe dysfunction, consistent with a right temporal focus on electroencephalography. At 4 months after the accident, she developed a psychological reaction consisting of nightmares, with reappearance of the complex visual hallucinations and a depressive syndrome. Using the European Cooperation for Lightning Detection network, a meteorological system for lightning surveillance, the exact geographical location and nature of the lightning strike were retrospectively retraced PMID:21734915

  8. Visual analytics of brain networks.

    PubMed

    Li, Kaiming; Guo, Lei; Faraco, Carlos; Zhu, Dajiang; Chen, Hanbo; Yuan, Yixuan; Lv, Jinglei; Deng, Fan; Jiang, Xi; Zhang, Tuo; Hu, Xintao; Zhang, Degang; Miller, L Stephen; Liu, Tianming

    2012-05-15

    Identification of regions of interest (ROIs) is a fundamental issue in brain network construction and analysis. Recent studies demonstrate that multimodal neuroimaging approaches and joint analysis strategies are crucial for accurate, reliable and individualized identification of brain ROIs. In this paper, we present a novel approach of visual analytics and its open-source software for ROI definition and brain network construction. By combining neuroscience knowledge and computational intelligence capabilities, visual analytics can generate accurate, reliable and individualized ROIs for brain networks via joint modeling of multimodal neuroimaging data and an intuitive and real-time visual analytics interface. Furthermore, it can be used as a functional ROI optimization and prediction solution when fMRI data is unavailable or inadequate. We have applied this approach to an operation span working memory fMRI/DTI dataset, a schizophrenia DTI/resting state fMRI (R-fMRI) dataset, and a mild cognitive impairment DTI/R-fMRI dataset, in order to demonstrate the effectiveness of visual analytics. Our experimental results are encouraging. Copyright © 2012 Elsevier Inc. All rights reserved.

  9. Parametric Study of Diffusion-Enhancement Networks for Spatiotemporal Grouping in Real-Time Artificial Vision

    DTIC Science & Technology

    1993-04-01

    suggesting it occurs in later visual motion processing (long-range or second-order system). STIMULUS PERCEPT L" FLASH DURATION FLASH DURATION (a) TIME ( b ...TIME Figure 2. Gamma motion. (a) A light of fixed spatial extent is illuminated then extim- guished. ( b ) The percept is of a light expanding and then...while smaller, type- B cells provide input to its parvocellular subdivision. From here the magnocellular pathway progresses up through visual cortex area V

  10. Free-Electron Laser (FEL) Utilization in Space Applications (Ship-Borne Pointing Accuracy, Deep-Space Communications, and Orbital Debris Tracking)

    DTIC Science & Technology

    2011-12-01

    Network STK Satellite Tool Kit WFOV Wide-Field-of-View xv ACKNOWLEDGMENTS I would like to first and foremost thank the Lord, Jesus Christ, our...frequencies in FSK is easily visualized . Table 5.1 details the phase difference between each state as the number of represented states is increased...assist in visualizing the phase separation when adding additional phases to the system. Each of the rows from Table 5.1 is displayed in Figure 5.10

  11. Learning and Recognition of a Non-conscious Sequence of Events in Human Primary Visual Cortex.

    PubMed

    Rosenthal, Clive R; Andrews, Samantha K; Antoniades, Chrystalina A; Kennard, Christopher; Soto, David

    2016-03-21

    Human primary visual cortex (V1) has long been associated with learning simple low-level visual discriminations [1] and is classically considered outside of neural systems that support high-level cognitive behavior in contexts that differ from the original conditions of learning, such as recognition memory [2, 3]. Here, we used a novel fMRI-based dichoptic masking protocol-designed to induce activity in V1, without modulation from visual awareness-to test whether human V1 is implicated in human observers rapidly learning and then later (15-20 min) recognizing a non-conscious and complex (second-order) visuospatial sequence. Learning was associated with a change in V1 activity, as part of a temporo-occipital and basal ganglia network, which is at variance with the cortico-cerebellar network identified in prior studies of "implicit" sequence learning that involved motor responses and visible stimuli (e.g., [4]). Recognition memory was associated with V1 activity, as part of a temporo-occipital network involving the hippocampus, under conditions that were not imputable to mechanisms associated with conscious retrieval. Notably, the V1 responses during learning and recognition separately predicted non-conscious recognition memory, and functional coupling between V1 and the hippocampus was enhanced for old retrieval cues. The results provide a basis for novel hypotheses about the signals that can drive recognition memory, because these data (1) identify human V1 with a memory network that can code complex associative serial visuospatial information and support later non-conscious recognition memory-guided behavior (cf. [5]) and (2) align with mouse models of experience-dependent V1 plasticity in learning and memory [6]. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. Network monitoring in the Tier2 site in Prague

    NASA Astrophysics Data System (ADS)

    Eliáš, Marek; Fiala, Lukáš; Horký, Jiří; Chudoba, Jiří; Kouba, Tomáš; Kundrát, Jan; Švec, Jan

    2011-12-01

    Network monitoring provides different types of view on the network traffic. It's output enables computing centre staff to make qualified decisions about changes in the organization of computing centre network and to spot possible problems. In this paper we present network monitoring framework used at Tier-2 in Prague in Institute of Physics (FZU). The framework consists of standard software and custom tools. We discuss our system for hardware failures detection using syslog logging and Nagios active checks, bandwidth monitoring of physical links and analysis of NetFlow exports from Cisco routers. We present tool for automatic detection of network layout based on SNMP. This tool also records topology changes into SVN repository. Adapted weathermap4rrd is used to visualize recorded data to get fast overview showing current bandwidth usage of links in network.

  13. Efficient Usage of Dense GNSS Networks in Central Europe for the Visualization and Investigation of Ionospheric TEC Variations

    PubMed Central

    Zanimonskiy, Yevgen M.; Yampolski, Yuri M.; Figurski, Mariusz

    2017-01-01

    The technique of the orthogonal projection of ionosphere electronic content variations for mapping total electron content (TEC) allows us to visualize ionospheric irregularities. For the reconstruction of global ionospheric characteristics, numerous global navigation satellite system (GNSS) receivers located in different regions of the Earth are used as sensors. We used dense GNSS networks in central Europe to detect and investigate a special type of plasma inhomogeneities, called travelling ionospheric disturbances (TID). Such use of GNSS sensors allows us to reconstruct the main TID parameters, such as spatial dimensions, velocities, and directions of their movement. The paper gives examples of the restoration of dynamic characteristics of ionospheric irregularities for quiet and disturbed geophysical conditions. Special attention is paid to the dynamics of ionospheric disturbances stimulated by the magnetic storms of two St. Patrick’s Days (17 March 2013 and 2015). Additional opportunities for the remote sensing of the ionosphere with the use of dense regional networks of GNSS receiving sensors have been noted too. PMID:28994718

  14. Efficient Usage of Dense GNSS Networks in Central Europe for the Visualization and Investigation of Ionospheric TEC Variations.

    PubMed

    Nykiel, Grzegorz; Zanimonskiy, Yevgen M; Yampolski, Yuri M; Figurski, Mariusz

    2017-10-10

    The technique of the orthogonal projection of ionosphere electronic content variations for mapping total electron content (TEC) allows us to visualize ionospheric irregularities. For the reconstruction of global ionospheric characteristics, numerous global navigation satellite system (GNSS) receivers located in different regions of the Earth are used as sensors. We used dense GNSS networks in central Europe to detect and investigate a special type of plasma inhomogeneities, called travelling ionospheric disturbances (TID). Such use of GNSS sensors allows us to reconstruct the main TID parameters, such as spatial dimensions, velocities, and directions of their movement. The paper gives examples of the restoration of dynamic characteristics of ionospheric irregularities for quiet and disturbed geophysical conditions. Special attention is paid to the dynamics of ionospheric disturbances stimulated by the magnetic storms of two St. Patrick's Days (17 March 2013 and 2015). Additional opportunities for the remote sensing of the ionosphere with the use of dense regional networks of GNSS receiving sensors have been noted too.

  15. 2014 Earth System Grid Federation and Ultrascale Visualization Climate Data Analysis Tools Conference Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Williams, Dean N.

    2015-01-27

    The climate and weather data science community met December 9–11, 2014, in Livermore, California, for the fourth annual Earth System Grid Federation (ESGF) and Ultrascale Visualization Climate Data Analysis Tools (UV-CDAT) Face-to-Face (F2F) Conference, hosted by the Department of Energy, National Aeronautics and Space Administration, National Oceanic and Atmospheric Administration, the European Infrastructure for the European Network of Earth System Modelling, and the Australian Department of Education. Both ESGF and UVCDATremain global collaborations committed to developing a new generation of open-source software infrastructure that provides distributed access and analysis to simulated and observed data from the climate and weather communities.more » The tools and infrastructure created under these international multi-agency collaborations are critical to understanding extreme weather conditions and long-term climate change. In addition, the F2F conference fosters a stronger climate and weather data science community and facilitates a stronger federated software infrastructure. The 2014 F2F conference detailed the progress of ESGF, UV-CDAT, and other community efforts over the year and sets new priorities and requirements for existing and impending national and international community projects, such as the Coupled Model Intercomparison Project Phase Six. Specifically discussed at the conference were project capabilities and enhancements needs for data distribution, analysis, visualization, hardware and network infrastructure, standards, and resources.« less

  16. Oscillatory network with self-organized dynamical connections for synchronization-based image segmentation.

    PubMed

    Kuzmina, Margarita; Manykin, Eduard; Surina, Irina

    2004-01-01

    An oscillatory network of columnar architecture located in 3D spatial lattice was recently designed by the authors as oscillatory model of the brain visual cortex. Single network oscillator is a relaxational neural oscillator with internal dynamics tunable by visual image characteristics - local brightness and elementary bar orientation. It is able to demonstrate either activity state (stable undamped oscillations) or "silence" (quickly damped oscillations). Self-organized nonlocal dynamical connections of oscillators depend on oscillator activity levels and orientations of cortical receptive fields. Network performance consists in transfer into a state of clusterized synchronization. At current stage grey-level image segmentation tasks are carried out by 2D oscillatory network, obtained as a limit version of the source model. Due to supplemented network coupling strength control the 2D reduced network provides synchronization-based image segmentation. New results on segmentation of brightness and texture images presented in the paper demonstrate accurate network performance and informative visualization of segmentation results, inherent in the model.

  17. Digital roadway interactive visualization and evaluation network applications to WSDOT operational data usage.

    DOT National Transportation Integrated Search

    2016-12-01

    DRIVE Net is a region-wide, Web-based transportation decision support system that adopts digital roadway maps as : the base, and provides data layers for integrating and analyzing a variety of data sources (e.g., traffic sensors, incident : records)....

  18. Disruptions of network connectivity predict impairment in multiple behavioral domains after stroke

    PubMed Central

    Ramsey, Lenny E.; Metcalf, Nicholas V.; Chacko, Ravi V.; Weinberger, Kilian; Baldassarre, Antonello; Hacker, Carl D.; Shulman, Gordon L.; Corbetta, Maurizio

    2016-01-01

    Deficits following stroke are classically attributed to focal damage, but recent evidence suggests a key role of distributed brain network disruption. We measured resting functional connectivity (FC), lesion topography, and behavior in multiple domains (attention, visual memory, verbal memory, language, motor, and visual) in a cohort of 132 stroke patients, and used machine-learning models to predict neurological impairment in individual subjects. We found that visual memory and verbal memory were better predicted by FC, whereas visual and motor impairments were better predicted by lesion topography. Attention and language deficits were well predicted by both. Next, we identified a general pattern of physiological network dysfunction consisting of decrease of interhemispheric integration and intrahemispheric segregation, which strongly related to behavioral impairment in multiple domains. Network-specific patterns of dysfunction predicted specific behavioral deficits, and loss of interhemispheric communication across a set of regions was associated with impairment across multiple behavioral domains. These results link key organizational features of brain networks to brain–behavior relationships in stroke. PMID:27402738

  19. The Worldviews Network: Digital Planetariums for Engaging Public Audiences in Global Change Issues

    NASA Astrophysics Data System (ADS)

    Wyatt, R. J.; Koontz, K.; Yu, K.; Gardiner, N.; Connolly, R.; Mcconville, D.

    2013-12-01

    Utilizing the capabilities of digital planetariums, the Denver Museum of Nature & Science, the California Academy of Sciences, NOVA/WGBH, The Elumenati, and affiliates of the National Oceanic & Atmospheric Administration formed the Worldviews Network. The network's mission is to place Earth in its cosmic context to encourage participants to explore connections between social & ecological issues in their backyards. Worldviews launched with informal science institution partners: the American Museum of Natural History, the Perot Museum of Nature & Science, the Journey Museum, the Bell Museum of Natural History, the University of Michigan Natural History Museum, and the National Environmental Modeling & Analysis Center. Worldviews uses immersive visualization technology to engage public audiences on issues of global environmental change at a bioregional level. An immersive planetarium show and dialogue deepens public engagement and awareness of complex human-natural system interactions. People have altered the global climate system. Our communities are increasingly vulnerable to extreme weather events. Land use decisions that people make every day put both human lives and biodiversity at risk through direct and indirect effects. The Worldviews programs demonstrate the complex linkages between Earth's physical and biological systems and their relationship to human health, agriculture, infrastructure, water resources, and energy. We have focused on critical thresholds, such as freshwater use, biodiversity loss, land use change, and anthropogenic changes to the nitrogen and phosphorus cycles. We have been guided by environmental literacy principles to help our audiences understand that humans drive current trends in coupled human-natural systems--and that humans could choose to play an important role in reversing these trends. Museum and planetarium staff members join the Worldviews Network team and external advisers to produce programs that span cosmic, global, and bioregional scales. Each presentation employs a 'See, Know, Do' transformative learning model. 'Seeing' involves the creation, presentation, and experience of viewing immersive visualizations within the planetarium to engage visitors' visual-spatial intelligence. For 'Knowing,' the narratives are constructed to help visitors understand the web of physical-ecological-social systems that interact on Earth. The 'Doing' component emerges from interaction among participants: for example, researchers and non-governmental organizations help audience members conceive of their own relationship to the highlighted issue and ways they may remain involved in systemically addressing problems the audience identifies.

  20. Using network projections to explore co-incidence and context in large clinical datasets: Application to homelessness among U.S. Veterans.

    PubMed

    Pettey, Warren B P; Toth, Damon J A; Redd, Andrew; Carter, Marjorie E; Samore, Matthew H; Gundlapalli, Adi V

    2016-06-01

    Network projections of data can provide an efficient format for data exploration of co-incidence in large clinical datasets. We present and explore the utility of a network projection approach to finding patterns in health care data that could be exploited to prevent homelessness among U.S. Veterans. We divided Veteran ICD-9-CM (ICD9) data into two time periods (0-59 and 60-364days prior to the first evidence of homelessness) and then used Pajek social network analysis software to visualize these data as three different networks. A multi-relational network simultaneously displayed the magnitude of ties between the most frequent ICD9 pairings. A new association network visualized ICD9 pairings that greatly increased or decreased. A signed, subtraction network visualized the presence, absence, and magnitude difference between ICD9 associations by time period. A cohort of 9468 U.S. Veterans was identified as having administrative evidence of homelessness and visits in both time periods. They were seen in 222,599 outpatient visits that generated 484,339 ICD9 codes (average of 11.4 (range 1-23) visits and 2.2 (range 1-60) ICD9 codes per visit). Using the three network projection methods, we were able to show distinct differences in the pattern of co-morbidities in the two time periods. In the more distant time period preceding homelessness, the network was dominated by routine health maintenance visits and physical ailment diagnoses. In the 59days immediately prior to the homelessness identification, alcohol related diagnoses along with economic circumstances such as unemployment, legal circumstances, along with housing instability were noted. Network visualizations of large clinical datasets traditionally treated as tabular and difficult to manipulate reveal rich, previously hidden connections between data variables related to homelessness. A key feature is the ability to visualize changes in variables with temporality and in proximity to the event of interest. These visualizations lend support to cognitive tasks such as exploration of large clinical datasets as a prelude to hypothesis generation. Published by Elsevier Inc.

  1. Measuring healthcare integration: Operationalization of a framework for a systems evaluation of palliative care structures, processes, and outcomes.

    PubMed

    Bainbridge, Daryl; Brazil, Kevin; Ploeg, Jenny; Krueger, Paul; Taniguchi, Alan

    2016-06-01

    Healthcare integration is a priority in many countries, yet there remains little direction on how to systematically evaluate this construct to inform further development. The examination of community-based palliative care networks provides an ideal opportunity for the advancement of integration measures, in consideration of how fundamental provider cohesion is to effective care at end of life. This article presents a variable-oriented analysis from a theory-based case study of a palliative care network to help bridge the knowledge gap in integration measurement. Data from a mixed-methods case study were mapped to a conceptual framework for evaluating integrated palliative care and a visual array depicting the extent of key factors in the represented palliative care network was formulated. The study included data from 21 palliative care network administrators, 86 healthcare professionals, and 111 family caregivers, all from an established palliative care network in Ontario, Canada. The framework used to guide this research proved useful in assessing qualities of integration and functioning in the palliative care network. The resulting visual array of elements illustrates that while this network performed relatively well at the multiple levels considered, room for improvement exists, particularly in terms of interventions that could facilitate the sharing of information. This study, along with the other evaluative examples mentioned, represents important initial attempts at empirically and comprehensively examining network-integrated palliative care and healthcare integration in general. © The Author(s) 2016.

  2. Experimenter's laboratory for visualized interactive science

    NASA Technical Reports Server (NTRS)

    Hansen, Elaine R.; Klemp, Marjorie K.; Lasater, Sally W.; Szczur, Marti R.; Klemp, Joseph B.

    1992-01-01

    The science activities of the 1990's will require the analysis of complex phenomena and large diverse sets of data. In order to meet these needs, we must take advantage of advanced user interaction techniques: modern user interface tools; visualization capabilities; affordable, high performance graphics workstations; and interoperable data standards and translator. To meet these needs, we propose to adopt and upgrade several existing tools and systems to create an experimenter's laboratory for visualized interactive science. Intuitive human-computer interaction techniques have already been developed and demonstrated at the University of Colorado. A Transportable Applications Executive (TAE+), developed at GSFC, is a powerful user interface tool for general purpose applications. A 3D visualization package developed by NCAR provides both color shaded surface displays and volumetric rendering in either index or true color. The Network Common Data Form (NetCDF) data access library developed by Unidata supports creation, access and sharing of scientific data in a form that is self-describing and network transparent. The combination and enhancement of these packages constitutes a powerful experimenter's laboratory capable of meeting key science needs of the 1990's. This proposal encompasses the work required to build and demonstrate this capability.

  3. Experimenter's laboratory for visualized interactive science

    NASA Technical Reports Server (NTRS)

    Hansen, Elaine R.; Klemp, Marjorie K.; Lasater, Sally W.; Szczur, Marti R.; Klemp, Joseph B.

    1993-01-01

    The science activities of the 1990's will require the analysis of complex phenomena and large diverse sets of data. In order to meet these needs, we must take advantage of advanced user interaction techniques: modern user interface tools; visualization capabilities; affordable, high performance graphics workstations; and interoperatable data standards and translator. To meet these needs, we propose to adopt and upgrade several existing tools and systems to create an experimenter's laboratory for visualized interactive science. Intuitive human-computer interaction techniques have already been developed and demonstrated at the University of Colorado. A Transportable Applications Executive (TAE+), developed at GSFC, is a powerful user interface tool for general purpose applications. A 3D visualization package developed by NCAR provides both color-shaded surface displays and volumetric rendering in either index or true color. The Network Common Data Form (NetCDF) data access library developed by Unidata supports creation, access and sharing of scientific data in a form that is self-describing and network transparent. The combination and enhancement of these packages constitutes a powerful experimenter's laboratory capable of meeting key science needs of the 1990's. This proposal encompasses the work required to build and demonstrate this capability.

  4. An intelligent surveillance platform for large metropolitan areas with dense sensor deployment.

    PubMed

    Fernández, Jorge; Calavia, Lorena; Baladrón, Carlos; Aguiar, Javier M; Carro, Belén; Sánchez-Esguevillas, Antonio; Alonso-López, Jesus A; Smilansky, Zeev

    2013-06-07

    This paper presents an intelligent surveillance platform based on the usage of large numbers of inexpensive sensors designed and developed inside the European Eureka Celtic project HuSIMS. With the aim of maximizing the number of deployable units while keeping monetary and resource/bandwidth costs at a minimum, the surveillance platform is based on the usage of inexpensive visual sensors which apply efficient motion detection and tracking algorithms to transform the video signal in a set of motion parameters. In order to automate the analysis of the myriad of data streams generated by the visual sensors, the platform's control center includes an alarm detection engine which comprises three components applying three different Artificial Intelligence strategies in parallel. These strategies are generic, domain-independent approaches which are able to operate in several domains (traffic surveillance, vandalism prevention, perimeter security, etc.). The architecture is completed with a versatile communication network which facilitates data collection from the visual sensors and alarm and video stream distribution towards the emergency teams. The resulting surveillance system is extremely suitable for its deployment in metropolitan areas, smart cities, and large facilities, mainly because cheap visual sensors and autonomous alarm detection facilitate dense sensor network deployments for wide and detailed coverage.

  5. Visual function in patients followed at a Veterans Affairs polytrauma network site: an electronic medical record review.

    PubMed

    Stelmack, Joan A; Frith, Theresa; Van Koevering, Denise; Rinne, Stephen; Stelmack, Thomas R

    2009-08-01

    This observational study describes the "Polytrauma System of Care" used by the Veterans Health Administration to guide medical care and rehabilitation of injured military personnel serving in Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) and reports the visual function of patients with polytrauma and/or traumatic brain injury (TBI) at the Hines, Illinois, Polytrauma Network Site (PNS). A retrospective medical record review was performed for 103 patients with polytrauma seen at the Hines PNS from October 2005 through March 2008 and 88 patients with TBI seen in the Hines TBI Clinic from December 2007 through March 2008. Visual symptoms were self-reported by 76% of patients with polytrauma and 75% of the patients with TBI. Problems with reading (polytrauma 60% and TBI 50%) and accommodation (polytrauma 30% and TBI 47%) were frequently found on eye examinations. Spectacles were the treatment most frequently prescribed (polytrauma 62% and TBI 78%). It is important for optometrists to be aware of the high rates of self-reported symptoms and visual problems in military personnel returning from deployment to the wars in Iraq and Afghanistan. Post-traumatic stress disorder and depression may complicate optometric evaluation and management.

  6. Global Precipitation Mission Visualization Tool

    NASA Technical Reports Server (NTRS)

    Schwaller, Mathew

    2011-01-01

    The Global Precipitation Mission (GPM) software provides graphic visualization tools that enable easy comparison of ground- and space-based radar observations. It was initially designed to compare ground radar reflectivity from operational, ground-based, S- and C-band meteorological radars with comparable measurements from the Tropical Rainfall Measuring Mission (TRMM) satellite's precipitation radar instrument. This design is also applicable to other groundbased and space-based radars, and allows both ground- and space-based radar data to be compared for validation purposes. The tool creates an operational system that routinely performs several steps. It ingests satellite radar data (precipitation radar data from TRMM) and groundbased meteorological radar data from a number of sources. Principally, the ground radar data comes from national networks of weather radars (see figure). The data ingested by the visualization tool must conform to the data formats used in GPM Validation Network Geometry-matched data product generation. The software also performs match-ups of the radar volume data for the ground- and space-based data, as well as statistical and graphical analysis (including two-dimensional graphical displays) on the match-up data. The visualization tool software is written in IDL, and can be operated either in the IDL development environment or as a stand-alone executable function.

  7. Using arborescences to estimate hierarchicalness in directed complex networks

    PubMed Central

    2018-01-01

    Complex networks are a useful tool for the understanding of complex systems. One of the emerging properties of such systems is their tendency to form hierarchies: networks can be organized in levels, with nodes in each level exerting control on the ones beneath them. In this paper, we focus on the problem of estimating how hierarchical a directed network is. We propose a structural argument: a network has a strong top-down organization if we need to delete only few edges to reduce it to a perfect hierarchy—an arborescence. In an arborescence, all edges point away from the root and there are no horizontal connections, both characteristics we desire in our idealization of what a perfect hierarchy requires. We test our arborescence score in synthetic and real-world directed networks against the current state of the art in hierarchy detection: agony, flow hierarchy and global reaching centrality. These tests highlight that our arborescence score is intuitive and we can visualize it; it is able to better distinguish between networks with and without a hierarchical structure; it agrees the most with the literature about the hierarchy of well-studied complex systems; and it is not just a score, but it provides an overall scheme of the underlying hierarchy of any directed complex network. PMID:29381761

  8. The Face-Processing Network Is Resilient to Focal Resection of Human Visual Cortex

    PubMed Central

    Jonas, Jacques; Gomez, Jesse; Maillard, Louis; Brissart, Hélène; Hossu, Gabriela; Jacques, Corentin; Loftus, David; Colnat-Coulbois, Sophie; Stigliani, Anthony; Barnett, Michael A.; Grill-Spector, Kalanit; Rossion, Bruno

    2016-01-01

    Human face perception requires a network of brain regions distributed throughout the occipital and temporal lobes with a right hemisphere advantage. Present theories consider this network as either a processing hierarchy beginning with the inferior occipital gyrus (occipital face area; IOG-faces/OFA) or a multiple-route network with nonhierarchical components. The former predicts that removing IOG-faces/OFA will detrimentally affect downstream stages, whereas the latter does not. We tested this prediction in a human patient (Patient S.P.) requiring removal of the right inferior occipital cortex, including IOG-faces/OFA. We acquired multiple fMRI measurements in Patient S.P. before and after a preplanned surgery and multiple measurements in typical controls, enabling both within-subject/across-session comparisons (Patient S.P. before resection vs Patient S.P. after resection) and between-subject/across-session comparisons (Patient S.P. vs controls). We found that the spatial topology and selectivity of downstream ipsilateral face-selective regions were stable 1 and 8 month(s) after surgery. Additionally, the reliability of distributed patterns of face selectivity in Patient S.P. before versus after resection was not different from across-session reliability in controls. Nevertheless, postoperatively, representations of visual space were typical in dorsal face-selective regions but atypical in ventral face-selective regions and V1 of the resected hemisphere. Diffusion weighted imaging in Patient S.P. and controls identifies white matter tracts connecting retinotopic areas to downstream face-selective regions, which may contribute to the stable and plastic features of the face network in Patient S.P. after surgery. Together, our results support a multiple-route network of face processing with nonhierarchical components and shed light on stable and plastic features of high-level visual cortex following focal brain damage. SIGNIFICANCE STATEMENT Brain networks consist of interconnected functional regions commonly organized in processing hierarchies. Prevailing theories predict that damage to the input of the hierarchy will detrimentally affect later stages. We tested this prediction with multiple brain measurements in a rare human patient requiring surgical removal of the putative input to a network processing faces. Surprisingly, the spatial topology and selectivity of downstream face-selective regions are stable after surgery. Nevertheless, representations of visual space were typical in dorsal face-selective regions but atypical in ventral face-selective regions and V1. White matter connections from outside the face network may support these stable and plastic features. As processing hierarchies are ubiquitous in biological and nonbiological systems, our results have pervasive implications for understanding the construction of resilient networks. PMID:27511014

  9. Speed of feedforward and recurrent processing in multilayer networks of integrate-and-fire neurons.

    PubMed

    Panzeri, S; Rolls, E T; Battaglia, F; Lavis, R

    2001-11-01

    The speed of processing in the visual cortical areas can be fast, with for example the latency of neuronal responses increasing by only approximately 10 ms per area in the ventral visual system sequence V1 to V2 to V4 to inferior temporal visual cortex. This has led to the suggestion that rapid visual processing can only be based on the feedforward connections between cortical areas. To test this idea, we investigated the dynamics of information retrieval in multiple layer networks using a four-stage feedforward network modelled with continuous dynamics with integrate-and-fire neurons, and associative synaptic connections between stages with a synaptic time constant of 10 ms. Through the implementation of continuous dynamics, we found latency differences in information retrieval of only 5 ms per layer when local excitation was absent and processing was purely feedforward. However, information latency differences increased significantly when non-associative local excitation was included. We also found that local recurrent excitation through associatively modified synapses can contribute significantly to processing in as little as 15 ms per layer, including the feedforward and local feedback processing. Moreover, and in contrast to purely feed-forward processing, the contribution of local recurrent feedback was useful and approximately this rapid even when retrieval was made difficult by noise. These findings suggest that cortical information processing can benefit from recurrent circuits when the allowed processing time per cortical area is at least 15 ms long.

  10. Microphone Array Phased Processing System (MAPPS): Version 4.0 Manual

    NASA Technical Reports Server (NTRS)

    Watts, Michael E.; Mosher, Marianne; Barnes, Michael; Bardina, Jorge

    1999-01-01

    A processing system has been developed to meet increasing demands for detailed noise measurement of individual model components. The Microphone Array Phased Processing System (MAPPS) uses graphical user interfaces to control all aspects of data processing and visualization. The system uses networked parallel computers to provide noise maps at selected frequencies in a near real-time testing environment. The system has been successfully used in the NASA Ames 7- by 10-Foot Wind Tunnel.

  11. 2005 Science and Technology for Chem-Bio Information Systems (S and T CBIS). Volume 2 - Wednesday

    DTIC Science & Technology

    2005-10-28

    historical example of using both an audible and visual alerting method. In April 1775, Revere hung two lanterns in the bell-tower of Christ Church in...individual building systems, outdoor systems, telephone notification systems and a network of alert sensors . Fire protection systems are often... sensor , be it a pushbutton at a gate, a wireless “panic” button or a CBRNE detector, may be programmed to trigger notifications without further

  12. Transportation networks : data, analysis, methodology development and visualization.

    DOT National Transportation Integrated Search

    2007-12-29

    This project provides data compilation, analysis methodology and visualization methodology for the current network : data assets of the Alabama Department of Transportation (ALDOT). This study finds that ALDOT is faced with a : considerable number of...

  13. VISUAL3D - An EIT network on visualization of geomodels

    NASA Astrophysics Data System (ADS)

    Bauer, Tobias

    2017-04-01

    When it comes to interpretation of data and understanding of deep geological structures and bodies at different scales then modelling tools and modelling experience is vital for deep exploration. Geomodelling provides a platform for integration of different types of data, including new kinds of information (e.g., new improved measuring methods). EIT Raw Materials, initiated by the EIT (European Institute of Innovation and Technology) and funded by the European Commission, is the largest and strongest consortium in the raw materials sector worldwide. The VISUAL3D network of infrastructure is an initiative by EIT Raw Materials and aims at bringing together partners with 3D-4D-visualisation infrastructure and 3D-4D-modelling experience. The recently formed network collaboration interlinks hardware, software and expert knowledge in modelling visualization and output. A special focus will be the linking of research, education and industry and integrating multi-disciplinary data and to visualize the data in three and four dimensions. By aiding network collaborations we aim at improving the combination of geomodels with differing file formats and data characteristics. This will create an increased competency in modelling visualization and the ability to interchange and communicate models more easily. By combining knowledge and experience in geomodelling with expertise in Virtual Reality visualization partners of EIT Raw Materials but also external parties will have the possibility to visualize, analyze and validate their geomodels in immersive VR-environments. The current network combines partners from universities, research institutes, geological surveys and industry with a strong background in geological 3D-modelling and 3D visualization and comprises: Luleå University of Technology, Geological Survey of Finland, Geological Survey of Denmark and Greenland, TUBA Freiberg, Uppsala University, Geological Survey of France, RWTH Aachen, DMT, KGHM Cuprum, Boliden, Montan Universität Leoben, Slovenian National Building and Civil Engineering Institute, Tallinn University of Technology and Turku University. The infrastructure within the network comprises different types of capturing and visualization hardware, ranging from high resolution cubes, VR walls, VR goggle solutions, high resolution photogrammetry, UAVs, lidar-scanners, and many more.

  14. Exploring Transformations in Caribbean Indigenous Social Networks through Visibility Studies: the Case of Late Pre-Colonial Landscapes in East-Guadeloupe (French West Indies).

    PubMed

    Brughmans, Tom; de Waal, Maaike S; Hofman, Corinne L; Brandes, Ulrik

    2018-01-01

    This paper presents a study of the visual properties of natural and Amerindian cultural landscapes in late pre-colonial East-Guadeloupe and of how these visual properties affected social interactions. Through a review of descriptive and formal visibility studies in Caribbean archaeology, it reveals that the ability of visual properties to affect past human behaviour is frequently evoked but the more complex of these hypotheses are rarely studied formally. To explore such complex hypotheses, the current study applies a range of techniques: total viewsheds, cumulative viewsheds, visual neighbourhood configurations and visibility networks. Experiments were performed to explore the control of seascapes, the functioning of hypothetical smoke signalling networks, the correlation of these visual properties with stylistic similarities of material culture found at sites and the change of visual properties over time. The results of these experiments suggest that only few sites in Eastern Guadeloupe are located in areas that are particularly suitable to visually control possible sea routes for short- and long-distance exchange; that visual control over sea areas was not a factor of importance for the existence of micro-style areas; that during the early phase of the Late Ceramic Age networks per landmass are connected and dense and that they incorporate all sites, a structure that would allow hypothetical smoke signalling networks; and that the visual properties of locations of the late sites Morne Souffleur and Morne Cybèle-1 were not ideal for defensive purposes. These results led us to propose a multi-scalar hypothesis for how lines of sight between settlements in the Lesser Antilles could have structured past human behaviour: short-distance visibility networks represent the structuring of navigation and communication within landmasses, whereas the landmasses themselves served as focal points for regional navigation and interaction. We conclude by emphasising that since our archaeological theories about visual properties usually take a multi-scalar landscape perspective, there is a need for this perspective to be reflected in our formal visibility methods as is made possible by the methods used in this paper.

  15. Real-time image processing for particle tracking velocimetry

    NASA Astrophysics Data System (ADS)

    Kreizer, Mark; Ratner, David; Liberzon, Alex

    2010-01-01

    We present a novel high-speed particle tracking velocimetry (PTV) experimental system. Its novelty is due to the FPGA-based, real-time image processing "on camera". Instead of an image, the camera transfers to the computer using a network card, only the relevant information of the identified flow tracers. Therefore, the system is ideal for the remote particle tracking systems in research and industrial applications, while the camera can be controlled and data can be transferred over any high-bandwidth network. We present the hardware and the open source software aspects of the PTV experiments. The tracking results of the new experimental system has been compared to the flow visualization and particle image velocimetry measurements. The canonical flow in the central cross section of a a cubic cavity (1:1:1 aspect ratio) in our lid-driven cavity apparatus is used for validation purposes. The downstream secondary eddy (DSE) is the sensitive portion of this flow and its size was measured with increasing Reynolds number (via increasing belt velocity). The size of DSE estimated from the flow visualization, PIV and compressed PTV is shown to agree within the experimental uncertainty of the methods applied.

  16. BiNGO: a Cytoscape plugin to assess overrepresentation of gene ontology categories in biological networks.

    PubMed

    Maere, Steven; Heymans, Karel; Kuiper, Martin

    2005-08-15

    The Biological Networks Gene Ontology tool (BiNGO) is an open-source Java tool to determine which Gene Ontology (GO) terms are significantly overrepresented in a set of genes. BiNGO can be used either on a list of genes, pasted as text, or interactively on subgraphs of biological networks visualized in Cytoscape. BiNGO maps the predominant functional themes of the tested gene set on the GO hierarchy, and takes advantage of Cytoscape's versatile visualization environment to produce an intuitive and customizable visual representation of the results.

  17. A Visually Attractive "Interconnected Network of Ideas" for Organizing the Teaching and Learning of Descriptive Inorganic Chemistry

    ERIC Educational Resources Information Center

    Rodgers, Glen E.

    2014-01-01

    A visually attractive interconnected network of ideas that helps general and second-year inorganic chemistry students make sense of the descriptive inorganic chemistry of the main-group elements is presented. The eight network components include the periodic law, the uniqueness principle, the diagonal effect, the inert-pair effect, the…

  18. Using Globe Browsing Systems in Planetariums to Take Audiences to Other Worlds.

    NASA Astrophysics Data System (ADS)

    Emmart, C. B.

    2014-12-01

    For the last decade planetariums have been adding capability of "full dome video" systems for both movie playback and interactive display. True scientific data visualization has now come to planetarium audiences as a means to display the actual three dimensional layout of the universe, the time based array of planets, minor bodies and spacecraft across the solar system, and now globe browsing systems to examine planetary bodies to the limits of resolutions acquired. Additionally, such planetarium facilities can be networked for simultaneous display across the world for wider audience and reach to authoritative scientist description and commentary. Data repositories such as NASA's Lunar Mapping and Modeling Project (LMMP), NASA GSFC's LANCE-MODIS, and others conforming to the Open Geospatial Consortium (OGC) standard of Web Map Server (WMS) protocols make geospatial data available for a growing number of dome supporting globe visualization systems. The immersive surround graphics of full dome video replicates our visual system creating authentic virtual scenes effectively placing audiences on location in some cases to other worlds only mapped robotically.

  19. Contextual Modulation is Related to Efficiency in a Spiking Network Model of Visual Cortex.

    PubMed

    Sharifian, Fariba; Heikkinen, Hanna; Vigário, Ricardo; Vanni, Simo

    2015-01-01

    In the visual cortex, stimuli outside the classical receptive field (CRF) modulate the neural firing rate, without driving the neuron by themselves. In the primary visual cortex (V1), such contextual modulation can be parametrized with an area summation function (ASF): increasing stimulus size causes first an increase and then a decrease of firing rate before reaching an asymptote. Earlier work has reported increase of sparseness when CRF stimulation is extended to its surroundings. However, there has been no clear connection between the ASF and network efficiency. Here we aimed to investigate possible link between ASF and network efficiency. In this study, we simulated the responses of a biomimetic spiking neural network model of the visual cortex to a set of natural images. We varied the network parameters, and compared the V1 excitatory neuron spike responses to the corresponding responses predicted from earlier single neuron data from primate visual cortex. The network efficiency was quantified with firing rate (which has direct association to neural energy consumption), entropy per spike and population sparseness. All three measures together provided a clear association between the network efficiency and the ASF. The association was clear when varying the horizontal connectivity within V1, which influenced both the efficiency and the distance to ASF, DAS. Given the limitations of our biophysical model, this association is qualitative, but nevertheless suggests that an ASF-like receptive field structure can cause efficient population response.

  20. A Simple Network Architecture Accounts for Diverse Reward Time Responses in Primary Visual Cortex

    PubMed Central

    Hussain Shuler, Marshall G.; Shouval, Harel Z.

    2015-01-01

    Many actions performed by animals and humans depend on an ability to learn, estimate, and produce temporal intervals of behavioral relevance. Exemplifying such learning of cued expectancies is the observation of reward-timing activity in the primary visual cortex (V1) of rodents, wherein neural responses to visual cues come to predict the time of future reward as behaviorally experienced in the past. These reward-timing responses exhibit significant heterogeneity in at least three qualitatively distinct classes: sustained increase or sustained decrease in firing rate until the time of expected reward, and a class of cells that reach a peak in firing at the expected delay. We elaborate upon our existing model by including inhibitory and excitatory units while imposing simple connectivity rules to demonstrate what role these inhibitory elements and the simple architectures play in sculpting the response dynamics of the network. We find that simply adding inhibition is not sufficient for obtaining the different distinct response classes, and that a broad distribution of inhibitory projections is necessary for obtaining peak-type responses. Furthermore, although changes in connection strength that modulate the effects of inhibition onto excitatory units have a strong impact on the firing rate profile of these peaked responses, the network exhibits robustness in its overall ability to predict the expected time of reward. Finally, we demonstrate how the magnitude of expected reward can be encoded at the expected delay in the network and how peaked responses express this reward expectancy. SIGNIFICANCE STATEMENT Heterogeneity in single-neuron responses is a common feature of neuronal systems, although sometimes, in theoretical approaches, it is treated as a nuisance and seldom considered as conveying a different aspect of a signal. In this study, we focus on the heterogeneous responses in the primary visual cortex of rodents trained with a predictable delayed reward time. We describe under what conditions this heterogeneity can arise by self-organization, and what information it can convey. This study, while focusing on a specific system, provides insight onto how heterogeneity can arise in general while also shedding light onto mechanisms of reinforcement learning using realistic biological assumptions. PMID:26377457

  1. New tools for non-invasive exploration of collagen network in cartilaginous tissue-engineered substitute.

    PubMed

    Henrionnet, Christel; Dumas, Dominique; Hupont, Sébastien; Stoltz, Jean François; Mainard, Didier; Gillet, Pierre; Pinzano, Astrid

    2017-01-01

    In tissue engineering approaches, the quality of substitutes is a key element to determine its ability to treat cartilage defects. However, in clinical practice, the evaluation of tissue-engineered cartilage substitute quality is not possible due to the invasiveness of the standard procedure, which is to date histology. The aim of this work was to validate a new innovative system performed from two-photon excitation laser adapted to an optical macroscope to evaluate at macroscopic scale the collagen network in cartilage tissue-engineered substitutes in confrontation with gold standard histologic techniques or immunohistochemistry to visualize type II collagen. This system permitted to differentiate the quality of collagen network between ITS and TGF-β1 treatments. Multiscale large field imaging combined to multimodality approaches (SHG-TCSPC) at macroscopical scale represent an innovative and non-invasive technique to monitor the quality of collagen network in cartilage tissue-engineered substitutes before in vivo implantation.

  2. Collision detection in complex dynamic scenes using an LGMD-based visual neural network with feature enhancement.

    PubMed

    Yue, Shigang; Rind, F Claire

    2006-05-01

    The lobula giant movement detector (LGMD) is an identified neuron in the locust brain that responds most strongly to the images of an approaching object such as a predator. Its computational model can cope with unpredictable environments without using specific object recognition algorithms. In this paper, an LGMD-based neural network is proposed with a new feature enhancement mechanism to enhance the expanded edges of colliding objects via grouped excitation for collision detection with complex backgrounds. The isolated excitation caused by background detail will be filtered out by the new mechanism. Offline tests demonstrated the advantages of the presented LGMD-based neural network in complex backgrounds. Real time robotics experiments using the LGMD-based neural network as the only sensory system showed that the system worked reliably in a wide range of conditions; in particular, the robot was able to navigate in arenas with structured surrounds and complex backgrounds.

  3. Situational Awareness of Network System Roles (SANSR)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huffer, Kelly M; Reed, Joel W

    In a large enterprise it is difficult for cyber security analysts to know what services and roles every machine on the network is performing (e.g., file server, domain name server, email server). Using network flow data, already collected by most enterprises, we developed a proof-of-concept tool that discovers the roles of a system using both clustering and categorization techniques. The tool's role information would allow cyber analysts to detect consequential changes in the network, initiate incident response plans, and optimize their security posture. The results of this proof-of-concept tool proved to be quite accurate on three real data sets. Wemore » will present the algorithms used in the tool, describe the results of preliminary testing, provide visualizations of the results, and discuss areas for future work. Without this kind of situational awareness, cyber analysts cannot quickly diagnose an attack or prioritize remedial actions.« less

  4. The role of pulvinar in the transmission of information in the visual hierarchy.

    PubMed

    Cortes, Nelson; van Vreeswijk, Carl

    2012-01-01

    VISUAL RECEPTIVE FIELD (RF) ATTRIBUTES IN VISUAL CORTEX OF PRIMATES HAVE BEEN EXPLAINED MAINLY FROM CORTICAL CONNECTIONS: visual RFs progress from simple to complex through cortico-cortical pathways from lower to higher levels in the visual hierarchy. This feedforward flow of information is paired with top-down processes through the feedback pathway. Although the hierarchical organization explains the spatial properties of RFs, is unclear how a non-linear transmission of activity through the visual hierarchy can yield smooth contrast response functions in all level of the hierarchy. Depending on the gain, non-linear transfer functions create either a bimodal response to contrast, or no contrast dependence of the response in the highest level of the hierarchy. One possible mechanism to regulate this transmission of visual contrast information from low to high level involves an external component that shortcuts the flow of information through the hierarchy. A candidate for this shortcut is the Pulvinar nucleus of the thalamus. To investigate representation of stimulus contrast a hierarchical model network of ten cortical areas is examined. In each level of the network, the activity from the previous layer is integrated and then non-linearly transmitted to the next level. The arrangement of interactions creates a gradient from simple to complex RFs of increasing size as one moves from lower to higher cortical levels. The visual input is modeled as a Gaussian random input, whose width codes for the contrast. This input is applied to the first area. The output activity ratio among different contrast values is analyzed for the last level to observe sensitivity to a contrast and contrast invariant tuning. For a purely cortical system, the output of the last area can be approximately contrast invariant, but the sensitivity to contrast is poor. To account for an alternative visual processing pathway, non-reciprocal connections from and to a parallel pulvinar like structure of nine areas is coupled to the system. Compared to the pure feedforward model, cortico-pulvino-cortical output presents much more sensitivity to contrast and has a similar level of contrast invariance of the tuning.

  5. The Role of Pulvinar in the Transmission of Information in the Visual Hierarchy

    PubMed Central

    Cortes, Nelson; van Vreeswijk, Carl

    2012-01-01

    Visual receptive field (RF) attributes in visual cortex of primates have been explained mainly from cortical connections: visual RFs progress from simple to complex through cortico-cortical pathways from lower to higher levels in the visual hierarchy. This feedforward flow of information is paired with top-down processes through the feedback pathway. Although the hierarchical organization explains the spatial properties of RFs, is unclear how a non-linear transmission of activity through the visual hierarchy can yield smooth contrast response functions in all level of the hierarchy. Depending on the gain, non-linear transfer functions create either a bimodal response to contrast, or no contrast dependence of the response in the highest level of the hierarchy. One possible mechanism to regulate this transmission of visual contrast information from low to high level involves an external component that shortcuts the flow of information through the hierarchy. A candidate for this shortcut is the Pulvinar nucleus of the thalamus. To investigate representation of stimulus contrast a hierarchical model network of ten cortical areas is examined. In each level of the network, the activity from the previous layer is integrated and then non-linearly transmitted to the next level. The arrangement of interactions creates a gradient from simple to complex RFs of increasing size as one moves from lower to higher cortical levels. The visual input is modeled as a Gaussian random input, whose width codes for the contrast. This input is applied to the first area. The output activity ratio among different contrast values is analyzed for the last level to observe sensitivity to a contrast and contrast invariant tuning. For a purely cortical system, the output of the last area can be approximately contrast invariant, but the sensitivity to contrast is poor. To account for an alternative visual processing pathway, non-reciprocal connections from and to a parallel pulvinar like structure of nine areas is coupled to the system. Compared to the pure feedforward model, cortico-pulvino-cortical output presents much more sensitivity to contrast and has a similar level of contrast invariance of the tuning. PMID:22654750

  6. Example of a Bayes network of relations among visual features

    NASA Astrophysics Data System (ADS)

    Agosta, John M.

    1991-10-01

    Bayes probability networks, also termed `influence diagrams,' promise to be a versatile, rigorous, and expressive uncertainty reasoning tool. This paper presents an example of how a Bayes network can express constraints among visual hypotheses. An example is presented of a model composed of cylindric primitives, inferred from a line drawing of a plumbing fixture. Conflict between interpretations of candidate cylinders is expressed by two parameters, one for the presence and one for the absence of visual evidence of their intersection. It is shown how `partial exclusion' relations are so generated and how they determine the degree of competition among the set of hypotheses. Solving this network obtains the assemblies of cylinders most likely to form an object.

  7. Entropy-based heavy tailed distribution transformation and visual analytics for monitoring massive network traffic

    NASA Astrophysics Data System (ADS)

    Han, Keesook J.; Hodge, Matthew; Ross, Virginia W.

    2011-06-01

    For monitoring network traffic, there is an enormous cost in collecting, storing, and analyzing network traffic datasets. Data mining based network traffic analysis has a growing interest in the cyber security community, but is computationally expensive for finding correlations between attributes in massive network traffic datasets. To lower the cost and reduce computational complexity, it is desirable to perform feasible statistical processing on effective reduced datasets instead of on the original full datasets. Because of the dynamic behavior of network traffic, traffic traces exhibit mixtures of heavy tailed statistical distributions or overdispersion. Heavy tailed network traffic characterization and visualization are important and essential tasks to measure network performance for the Quality of Services. However, heavy tailed distributions are limited in their ability to characterize real-time network traffic due to the difficulty of parameter estimation. The Entropy-Based Heavy Tailed Distribution Transformation (EHTDT) was developed to convert the heavy tailed distribution into a transformed distribution to find the linear approximation. The EHTDT linearization has the advantage of being amenable to characterize and aggregate overdispersion of network traffic in realtime. Results of applying the EHTDT for innovative visual analytics to real network traffic data are presented.

  8. Neurophysiology underlying influence of stimulus reliability on audiovisual integration.

    PubMed

    Shatzer, Hannah; Shen, Stanley; Kerlin, Jess R; Pitt, Mark A; Shahin, Antoine J

    2018-01-24

    We tested the predictions of the dynamic reweighting model (DRM) of audiovisual (AV) speech integration, which posits that spectrotemporally reliable (informative) AV speech stimuli induce a reweighting of processing from low-level to high-level auditory networks. This reweighting decreases sensitivity to acoustic onsets and in turn increases tolerance to AV onset asynchronies (AVOA). EEG was recorded while subjects watched videos of a speaker uttering trisyllabic nonwords that varied in spectrotemporal reliability and asynchrony of the visual and auditory inputs. Subjects judged the stimuli as in-sync or out-of-sync. Results showed that subjects exhibited greater AVOA tolerance for non-blurred than blurred visual speech and for less than more degraded acoustic speech. Increased AVOA tolerance was reflected in reduced amplitude of the P1-P2 auditory evoked potentials, a neurophysiological indication of reduced sensitivity to acoustic onsets and successful AV integration. There was also sustained visual alpha band (8-14 Hz) suppression (desynchronization) following acoustic speech onsets for non-blurred vs. blurred visual speech, consistent with continuous engagement of the visual system as the speech unfolds. The current findings suggest that increased spectrotemporal reliability of acoustic and visual speech promotes robust AV integration, partly by suppressing sensitivity to acoustic onsets, in support of the DRM's reweighting mechanism. Increased visual signal reliability also sustains the engagement of the visual system with the auditory system to maintain alignment of information across modalities. © 2018 Federation of European Neuroscience Societies and John Wiley & Sons Ltd.

  9. Electronic approaches to restoration of sight

    NASA Astrophysics Data System (ADS)

    Goetz, G. A.; Palanker, D. V.

    2016-09-01

    Retinal prostheses are a promising means for restoring sight to patients blinded by the gradual atrophy of photoreceptors due to retinal degeneration. They are designed to reintroduce information into the visual system by electrically stimulating surviving neurons in the retina. This review outlines the concepts and technologies behind two major approaches to retinal prosthetics: epiretinal and subretinal. We describe how the visual system responds to electrical stimulation. We highlight major differences between direct encoding of the retinal output with epiretinal stimulation, and network-mediated response with subretinal stimulation. We summarize results of pre-clinical evaluation of prosthetic visual functions in- and ex vivo, as well as the outcomes of current clinical trials of various retinal implants. We also briefly review alternative, non-electronic, approaches to restoration of sight to the blind, and conclude by suggesting some perspectives for future advancement in the field.

  10. Electronic Approaches to Restoration of Sight

    PubMed Central

    Goetz, G A; Palanker, D V

    2016-01-01

    Retinal prostheses are a promising means for restoring sight to patients blinded by the gradual atrophy of photoreceptors due to retinal degeneration. They are designed to reintroduce information into the visual system by electrically stimulating surviving neurons in the retina. This review outlines the concepts and technologies behind two major approaches to retinal prosthetics: epiretinal and subretinal. We describe how the visual system responds to electrical stimulation. We highlight major differences between direct encoding of the retinal output with epiretinal stimulation, and network-mediated response with subretinal stimulation. We summarize results of pre-clinical evaluation of prosthetic visual functions in- and ex-vivo, as well as the outcomes of current clinical trials of various retinal implants. We also briefly review alternative, non-electronic, approaches to restoration of sight to the blind, and conclude by suggesting some perspectives for future advancement in the field. PMID:27502748

  11. The Study of Learners' Preference for Visual Complexity on Small Screens of Mobile Computers Using Neural Networks

    ERIC Educational Resources Information Center

    Wang, Lan-Ting; Lee, Kun-Chou

    2014-01-01

    The vision plays an important role in educational technologies because it can produce and communicate quite important functions in teaching and learning. In this paper, learners' preference for the visual complexity on small screens of mobile computers is studied by neural networks. The visual complexity in this study is divided into five…

  12. Review On Applications Of Neural Network To Computer Vision

    NASA Astrophysics Data System (ADS)

    Li, Wei; Nasrabadi, Nasser M.

    1989-03-01

    Neural network models have many potential applications to computer vision due to their parallel structures, learnability, implicit representation of domain knowledge, fault tolerance, and ability of handling statistical data. This paper demonstrates the basic principles, typical models and their applications in this field. Variety of neural models, such as associative memory, multilayer back-propagation perceptron, self-stabilized adaptive resonance network, hierarchical structured neocognitron, high order correlator, network with gating control and other models, can be applied to visual signal recognition, reinforcement, recall, stereo vision, motion, object tracking and other vision processes. Most of the algorithms have been simulated on com-puters. Some have been implemented with special hardware. Some systems use features, such as edges and profiles, of images as the data form for input. Other systems use raw data as input signals to the networks. We will present some novel ideas contained in these approaches and provide a comparison of these methods. Some unsolved problems are mentioned, such as extracting the intrinsic properties of the input information, integrating those low level functions to a high-level cognitive system, achieving invariances and other problems. Perspectives of applications of some human vision models and neural network models are analyzed.

  13. Patterns of thought: Population variation in the associations between large-scale network organisation and self-reported experiences at rest.

    PubMed

    Wang, Hao-Ting; Bzdok, Danilo; Margulies, Daniel; Craddock, Cameron; Milham, Michael; Jefferies, Elizabeth; Smallwood, Jonathan

    2018-08-01

    Contemporary cognitive neuroscience recognises unconstrained processing varies across individuals, describing variation in meaningful attributes, such as intelligence. It may also have links to patterns of on-going experience. This study examined whether dimensions of population variation in different modes of unconstrained processing can be described by the associations between patterns of neural activity and self-reports of experience during the same period. We selected 258 individuals from a publicly available data set who had measures of resting-state functional magnetic resonance imaging, and self-reports of experience during the scan. We used machine learning to determine patterns of association between the neural and self-reported data, finding variation along four dimensions. 'Purposeful' experiences were associated with lower connectivity - in particular default mode and limbic networks were less correlated with attention and sensorimotor networks. 'Emotional' experiences were associated with higher connectivity, especially between limbic and ventral attention networks. Experiences focused on themes of 'personal importance' were associated with reduced functional connectivity within attention and control systems. Finally, visual experiences were associated with stronger connectivity between visual and other networks, in particular the limbic system. Some of these patterns had contrasting links with cognitive function as assessed in a separate laboratory session - purposeful thinking was linked to greater intelligence and better abstract reasoning, while a focus on personal importance had the opposite relationship. Together these findings are consistent with an emerging literature on unconstrained states and also underlines that these states are heterogeneous, with distinct modes of population variation reflecting the interplay of different large-scale networks. Copyright © 2018 Elsevier Inc. All rights reserved.

  14. Industrial WSN Based on IR-UWB and a Low-Latency MAC Protocol

    NASA Astrophysics Data System (ADS)

    Reinhold, Rafael; Underberg, Lisa; Wulf, Armin; Kays, Ruediger

    2016-07-01

    Wireless sensor networks for industrial communication require high reliability and low latency. As current wireless sensor networks do not entirely meet these requirements, novel system approaches need to be developed. Since ultra wideband communication systems seem to be a promising approach, this paper evaluates the performance of the IEEE 802.15.4 impulse-radio ultra-wideband physical layer and the IEEE 802.15.4 Low Latency Deterministic Network (LLDN) MAC for industrial applications. Novel approaches and system adaptions are proposed to meet the application requirements. In this regard, a synchronization approach based on circular average magnitude difference functions (CAMDF) and on a clean template (CT) is presented for the correlation receiver. An adapted MAC protocol titled aggregated low latency (ALL) MAC is proposed to significantly reduce the resulting latency. Based on the system proposals, a hardware prototype has been developed, which proves the feasibility of the system and visualizes the real-time performance of the MAC protocol.

  15. Visual Analysis of Cloud Computing Performance Using Behavioral Lines.

    PubMed

    Muelder, Chris; Zhu, Biao; Chen, Wei; Zhang, Hongxin; Ma, Kwan-Liu

    2016-02-29

    Cloud computing is an essential technology to Big Data analytics and services. A cloud computing system is often comprised of a large number of parallel computing and storage devices. Monitoring the usage and performance of such a system is important for efficient operations, maintenance, and security. Tracing every application on a large cloud system is untenable due to scale and privacy issues. But profile data can be collected relatively efficiently by regularly sampling the state of the system, including properties such as CPU load, memory usage, network usage, and others, creating a set of multivariate time series for each system. Adequate tools for studying such large-scale, multidimensional data are lacking. In this paper, we present a visual based analysis approach to understanding and analyzing the performance and behavior of cloud computing systems. Our design is based on similarity measures and a layout method to portray the behavior of each compute node over time. When visualizing a large number of behavioral lines together, distinct patterns often appear suggesting particular types of performance bottleneck. The resulting system provides multiple linked views, which allow the user to interactively explore the data by examining the data or a selected subset at different levels of detail. Our case studies, which use datasets collected from two different cloud systems, show that this visual based approach is effective in identifying trends and anomalies of the systems.

  16. Use of a Neural Net to Model the Impact of Optical Coherence Tomography Abnormalities on Vision in Age-related Macular Degeneration.

    PubMed

    Aslam, Tariq M; Zaki, Haider R; Mahmood, Sajjad; Ali, Zaria C; Ahmad, Nur A; Thorell, Mariana R; Balaskas, Konstantinos

    2018-01-01

    To develop a neural network for the estimation of visual acuity from optical coherence tomography (OCT) images of patients with neovascular age-related macular degeneration (AMD) and to demonstrate its use to model the impact of specific controlled OCT changes on vision. Artificial intelligence (neural network) study. We assessed 1400 OCT scans of patients with neovascular AMD. Fifteen physical features for each eligible OCT, as well as patient age, were used as input data and corresponding recorded visual acuity as the target data to train, validate, and test a supervised neural network. We then applied this network to model the impact on acuity of defined OCT changes in subretinal fluid, subretinal hyperreflective material, and loss of external limiting membrane (ELM) integrity. A total of 1210 eligible OCT scans were analyzed, resulting in 1210 data points, which were each 16-dimensional. A 10-layer feed-forward neural network with 1 hidden layer of 10 neurons was trained to predict acuity and demonstrated a root mean square error of 8.2 letters for predicted compared to actual visual acuity and a mean regression coefficient of 0.85. A virtual model using this network demonstrated the relationship of visual acuity to specific, programmed changes in OCT characteristics. When ELM is intact, there is a shallow decline in acuity with increasing subretinal fluid but a much steeper decline with equivalent increasing subretinal hyperreflective material. When ELM is not intact, all visual acuities are reduced. Increasing subretinal hyperreflective material or subretinal fluid in this circumstance reduces vision further still, but with a smaller gradient than when ELM is intact. The supervised machine learning neural network developed is able to generate an estimated visual acuity value from OCT images in a population of patients with AMD. These findings should be of clinical and research interest in macular degeneration, for example in estimating visual prognosis or highlighting the importance of developing treatments targeting more visually destructive pathologies. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Distributed control system in a car-body inspection station

    NASA Astrophysics Data System (ADS)

    Yang, Xueyou; Ren, Dahai; Ye, Shenghua; Lu, Hongbo; Duan, Jilin

    1997-06-01

    In this paper, a distributed control network in autocar-body visual inspection station is presented in which PC is used as the host processor and single-chip microcomputers are employed as slave controllers. The physical interface of the control network and the relevant hardware are introduced in this paper. Meanwhile, a minute research on data communication is performed, relevant protocols on data framing, instruction codes and channel access methods have been laid down and part of related software is presented.

  18. MetaMapR: pathway independent metabolomic network analysis incorporating unknowns.

    PubMed

    Grapov, Dmitry; Wanichthanarak, Kwanjeera; Fiehn, Oliver

    2015-08-15

    Metabolic network mapping is a widely used approach for integration of metabolomic experimental results with biological domain knowledge. However, current approaches can be limited by biochemical domain or pathway knowledge which results in sparse disconnected graphs for real world metabolomic experiments. MetaMapR integrates enzymatic transformations with metabolite structural similarity, mass spectral similarity and empirical associations to generate richly connected metabolic networks. This open source, web-based or desktop software, written in the R programming language, leverages KEGG and PubChem databases to derive associations between metabolites even in cases where biochemical domain or molecular annotations are unknown. Network calculation is enhanced through an interface to the Chemical Translation System, which allows metabolite identifier translation between >200 common biochemical databases. Analysis results are presented as interactive visualizations or can be exported as high-quality graphics and numerical tables which can be imported into common network analysis and visualization tools. Freely available at http://dgrapov.github.io/MetaMapR/. Requires R and a modern web browser. Installation instructions, tutorials and application examples are available at http://dgrapov.github.io/MetaMapR/. ofiehn@ucdavis.edu. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  19. Real-time network security situation visualization and threat assessment based on semi-Markov process

    NASA Astrophysics Data System (ADS)

    Chen, Junhua

    2013-03-01

    To cope with a large amount of data in current sensed environments, decision aid tools should provide their understanding of situations in a time-efficient manner, so there is an increasing need for real-time network security situation awareness and threat assessment. In this study, the state transition model of vulnerability in the network based on semi-Markov process is proposed at first. Once events are triggered by an attacker's action or system response, the current states of the vulnerabilities are known. Then we calculate the transition probabilities of the vulnerability from the current state to security failure state. Furthermore in order to improve accuracy of our algorithms, we adjust the probabilities that they exploit the vulnerability according to the attacker's skill level. In the light of the preconditions and post-conditions of vulnerabilities in the network, attack graph is built to visualize security situation in real time. Subsequently, we predict attack path, recognize attack intention and estimate the impact through analysis of attack graph. These help administrators to insight into intrusion steps, determine security state and assess threat. Finally testing in a network shows that this method is reasonable and feasible, and can undertake tremendous analysis task to facilitate administrators' work.

  20. BNDB - the Biochemical Network Database.

    PubMed

    Küntzer, Jan; Backes, Christina; Blum, Torsten; Gerasch, Andreas; Kaufmann, Michael; Kohlbacher, Oliver; Lenhof, Hans-Peter

    2007-10-02

    Technological advances in high-throughput techniques and efficient data acquisition methods have resulted in a massive amount of life science data. The data is stored in numerous databases that have been established over the last decades and are essential resources for scientists nowadays. However, the diversity of the databases and the underlying data models make it difficult to combine this information for solving complex problems in systems biology. Currently, researchers typically have to browse several, often highly focused, databases to obtain the required information. Hence, there is a pressing need for more efficient systems for integrating, analyzing, and interpreting these data. The standardization and virtual consolidation of the databases is a major challenge resulting in a unified access to a variety of data sources. We present the Biochemical Network Database (BNDB), a powerful relational database platform, allowing a complete semantic integration of an extensive collection of external databases. BNDB is built upon a comprehensive and extensible object model called BioCore, which is powerful enough to model most known biochemical processes and at the same time easily extensible to be adapted to new biological concepts. Besides a web interface for the search and curation of the data, a Java-based viewer (BiNA) provides a powerful platform-independent visualization and navigation of the data. BiNA uses sophisticated graph layout algorithms for an interactive visualization and navigation of BNDB. BNDB allows a simple, unified access to a variety of external data sources. Its tight integration with the biochemical network library BN++ offers the possibility for import, integration, analysis, and visualization of the data. BNDB is freely accessible at http://www.bndb.org.

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