Epidemiology and clinical course of Behçet's disease in the Reggio Emilia area of Northern Italy: a seventeen-year population-based study.

PubMed

Salvarani, Carlo; Pipitone, Nicolò; Catanoso, Maria Grazia; Cimino, Luca; Tumiati, Bruno; Macchioni, Pierluigi; Bajocchi, Gianluigi; Olivieri, Ignazio; Boiardi, Luigi

2007-02-15

To investigate the epidemiology and clinical course of Behçet's disease (BD) over a 17-year period in a defined area of northern Italy. All patients with incident BD diagnosed over a 17-year period (from January 1, 1988 to December 31, 2004) living in the Reggio Emilia area were identified through the following sources: physicians at Reggio Emilia Hospital, medical practitioners, and community-based specialists. We identified all patients registered in a centralized index and in the Reggio Emilia district database for rare diseases. Patients were followed up from the time of diagnosis until either their death or April 1, 2005. Eighteen patients (9 men and 9 women) had complete BD. Mean +/- SD age at diagnosis was 33 +/- 7 years. The incidence rate of BD was 0.24 per 100,000. The prevalence of BD on January 1, 2005 was 3.8 per 100,000. No patients died during the followup period. Although all patients developed oral ulceration during the disease course, 22.2% had no oral lesions at disease onset. Eye disease occurred in 55.6%. Ocular disease was more common in men and appeared at disease onset or within the first few years of disease onset (median 3 years). Only 1 patient had loss of useful vision in at least 1 eye at the end of followup. In all affected patients, visual acuity improved once treatment was started. This population-based study is the first to report the prevalence and incidence of BD in Italy. In Italian patients, BD is nonfatal and the prognosis of eye disease is good.

Landslide early warning based on failure forecast models: the example of the Mt. de La Saxe rockslide, northern Italy

NASA Astrophysics Data System (ADS)

Manconi, A.; Giordan, D.

2015-07-01

We apply failure forecast models by exploiting near-real-time monitoring data for the La Saxe rockslide, a large unstable slope threatening Aosta Valley in northern Italy. Starting from the inverse velocity theory, we analyze landslide surface displacements automatically and in near real time on different temporal windows and apply straightforward statistical methods to obtain confidence intervals on the estimated time of failure. Here, we present the result obtained for the La Saxe rockslide, a large unstable slope located in Aosta Valley, northern Italy. Based on this case study, we identify operational thresholds that are established on the reliability of the forecast models. Our approach is aimed at supporting the management of early warning systems in the most critical phases of the landslide emergency.

Malthusian dynamics in a diverging Europe: Northern Italy, 1650-1881.

PubMed

Fernihough, Alan

2013-02-01

Recent empirical research questions the validity of using Malthusian theory in preindustrial England. Using real wage and vital rate data for the years 1650-1881, I provide empirical estimates for a different region: Northern Italy. The empirical methodology is theoretically underpinned by a simple Malthusian model, in which population, real wages, and vital rates are determined endogenously. My findings strongly support the existence of a Malthusian economy wherein population growth decreased living standards, which in turn influenced vital rates. However, these results also demonstrate how the system is best characterized as one of weak homeostasis. Furthermore, there is no evidence of Boserupian effects given that increases in population failed to spur any sustained technological progress.

Global prostate cancer incidence and the migration, settlement, and admixture history of the Northern Europeans

PubMed Central

Gunderson, Kristin; Wang, Christopher Y.; Wang, Ruoxiang

2012-01-01

The most salient feature of prostate cancer is its striking ethnic disparity. High incidences of the disease are documented in two ethnic groups: descendents of the Northern Europeans and African Americans. Other groups, including native Africans, are much less susceptible to the disease. Given that many risk factors may contribute to carcinogenesis, an etiological cause for the ethnic disparity remains to be defined. By analyzing the global prostate cancer incidence data, we found that distribution of prostate cancer incidence coincides with the migration and settlement history of Northern Europeans. The incidences in other ethnic groups correlate to the settlement history and extent of admixture of the Europeans. This study suggests that prostate cancer has been spread by the transmission of a genetic susceptibility that resides in the Northern European genome. PMID:21167803

Coral-algal Reef Complex of Vigoleno, Piacenza, Northern Italy

NASA Astrophysics Data System (ADS)

Russo, Antonio; Artoni, Andrea; Scarponi, Daniele; Serventi, Paolo

2017-12-01

During the late Miocene, reef complexes characterised by poorly diversified coral associations (mainly Porites, occasionally associated with Tarbellastraea and/or Siderastraea), became widespread in the Mediterranean area. One of these complexes crops out at Vigoleno (Castell’Arquato, Piacenza, Northern Italy). According to the regional palaeogeographic and palinspastic reconstructions, it can be considered up to now the northernmost late Miocene (Tortonian-Messinian) reef of the Mediterranean area. Despite the limited outcropping and the faulting, the multidisciplinary investigations reveal the anatomy of this reef complex along two reference sections. In addition, a marked cyclicity characterises both carbonate and siliciclastic deposits of the Vigoleno wedge-top basin. At present, the lack of reliable geochronological markers and unsuitability of the material for stable isotope analyses are not sufficient to constrain the time-span and the main controlling environmental factors of these depositional cycles.

Incidence of the mucopolysaccharidoses in Northern Ireland.

PubMed

Nelson, J

1997-12-01

An epidemiological study of the mucopolysaccharidoses (MPS) in Northern Ireland using multiple ascertainment sources was carried out and the incidence rate for the period 1958-1985 was estimated. An incidence of approximately 1 in 76,000 live births was obtained for MPS 1H (Hurler phenotype); 1 in 280,000 for MPS 1 H/S (Hurler/Scheie phenotype); 1 in 140,000 live births (1 in 72,000 male live births) for MPS II (Hunter syndrome); 1 in 280,000 for MPS III (Sanfilippo syndrome) and 1 in 76,000 for MPS IV A (Morquio syndrome type A). No cases of MPS IS (Scheie phenotype), MPS IV B (Morquio syndrome type B) or MPS VI (Maroteaux-Lamy syndrome) were ascertained during the study period. Three cases of non-immune hydrops fetalis born to consanguineous parents were thought to be due to beta-glucuronidase deficiency (MPS VII) on the basis of placental histology and enzyme studies on both parents but no living cases of MPS VII were ascertained. The overall incidence for all types of mucopolysaccharidosis was approximately 1 in 25,000 live births. A comparison is made with incidence estimates obtained from other published studies.

Occupational cancer in Italy.

PubMed Central

Merler, E; Vineis, P; Alhaique, D; Miligi, L

1999-01-01

This article is a discussion of occupational cancer in Italy. The introduction provides the necessary context of Italian industrialization and occupational health regulation. This is followed by a review of Italian epidemiologic studies of occupational cancer risks considered in terms of relative measures of risk and attributable risk of carcinogenic agents or exposure circumstances. We attempt to establish the number of workers exposed to carcinogens in Italy and the intensity of their exposures. Finally, the Italian system of compensation for occupational cancer is discussed. Several cohort and case-control studies have addressed the issue of occupational risks, mostly among male workers. The results of these studies suggest that the growing incidence of and mortality by mesothelioma is explained by the widespread and intense exposure to asbestos in some Italian industrial settings. A high attributable risk of lung tumors among male populations in industrial areas of northern Italy is explained by occupational exposures. However, insufficient data are available for clear definition of the extent and intensity of occupational exposure to carcinogenic substances. In Italy, we must prioritize and maximize resources in occupational cancer epidemiology and revitalize the role of national institutions. Recent legislation has established new regulations on the handling of carcinogenic substances in industrial settings, a new list of occupational diseases, and a national registry of mesothelioma linked to asbestos exposure. These legislative changes are expected to have positive effects. PMID:10350509

Measles re-emergence in Northern Italy: Pathways of measles virus genotype D8, 2013-2014.

PubMed

Amendola, Antonella; Bianchi, Silvia; Lai, Alessia; Canuti, Marta; Piralla, Antonio; Baggieri, Melissa; Ranghiero, Alberto; Piatti, Alessandra; Tanzi, Elisabetta; Zehender, Gianguglielmo; Magurano, Fabio; Baldanti, Fausto

2017-03-01

Molecular surveillance and advanced phylogenetic methods are important tools to track the pathways of Measles virus (MV) genotypes, provide evidence for the interruption of endemic transmission and verify the elimination of the disease. The aims of this study were to describe the genetic profile of MV genotype D8 (D8-MV) strains circulating in Northern Italy (Lombardy Region) during the 2013-2014 period and to analyze the transmission chains and estimate the introduction time points using a phylogenetic approach. Forty-four strains of D8-MV identified from 12 outbreaks and 28 cases reported as sporadic were analyzed. Molecular analysis was performed by sequencing the highly variable 450nt region of the N gene of MV genome (N-450), as recommended by the WHO. Phylogenetic analyses and tree time-scaled reconstruction were performed with BEAST software. We could trace back the transmission pathways that resulted in three chains of transmission, two introductions with limited spread (two familiar outbreaks), and two single introductions (true sporadic cases). The D8-Taunton transmission chain, which was involved in 7 outbreaks and 13 sporadic cases, was endemic during the studied period. Furthermore, two novel local variants emerged independently in March 2014 and caused two transmission chains linked to at least 3 outbreaks. Overall, viral diversity was high and strains belonging to 5 different variants were identified. The results of this study clearly demonstrate that multiple lineages of D8-MV co-circulated in Northern Italy. Measles can be considered a re-emerging disease in Italy and additional efforts are necessary to achieve measles elimination goal. Copyright © 2016 Elsevier B.V. All rights reserved.

Petroleum systems of the Po Basin Province of northern Italy and the northern Adriatic Sea; Porto Garibaldi (biogenic), Meride/Riva di Solto (thermal), and Marnoso Arenacea (thermal)

USGS Publications Warehouse

Lindquist, Sandra J.

1999-01-01

The Porto Garibaldi total petroleum system dominates the Po Basin Province of onshore northern Italy and offshore Italy and Croatia in the northern Adriatic Sea. Porto Garibaldi contains Pliocene (primarily) and Pleistocene (secondarily) biogenic gas ? approximately 16 TCF (2.66 BBOE) ultimately recoverable ? accumulated in co-eval siliciclastic reservoirs. This area was the northwestern edge of the Gondwanan (African) continental plate in pre-Hercynian time until the assembly of Pangea, a dominantly carbonate passive continental margin during the Mesozoic breakup of Pangea, and a Cenozoic collision zone with siliciclastic foredeep and foreland regions surrounded by thrust belts. At least two other petroleum systems, with Triassic (Meride / Riva di Solto) and Miocene (Marnoso Arenacea) source rocks, contribute oil and thermal gas reserves (nearly 1 BBOE) to the province. The major time of hydrocarbon expulsion of the thermal systems was Late Neogene during the Alpine and Apennine orogenies. Local Mesozoic oil expulsion from Triassic rocks also occurred, but those oils either were not trapped or were leaked from faulty traps through time.

[Mortality study in metal electroplating workers in Bologna (Northern Italy)].

PubMed

Gerosa, Alberto; Scarnato, Corrado; Giacomozzi, Giuseppe; d'Errico, Angelo

2013-01-01

to investigate general and cause-specific mortality of workers exposed to metals and other chemicals in the electroplating industry in Bologna Province. factory records of workers employed in 90 electroplating companies present in 1995 were used to build a cohort of subjects potentially exposed to carcinogenic and other substances in this industry, defined as "revised cohort", which was followed-up for mortality from 1960, or since first employment in an electroplating company if later, to 2008. Mortality risk was also examined separately in a subset of the cohort, composed of workers with at least one year of employment in electroplating, denominated "final cohort". Death rates of residents in Emilia-Romagna Region (Northern Italy) were used as a reference. follow-up completeness was 99%. During the observation period, 533 deaths out of 2,983 subjects were observed in the revised cohort and 317 out of 1,739 in the final cohort. Significantly increased Standardized Mortality Ratios were estimated for overall mortality and for mortality from AIDS in the revised cohort and for bladder and rectal cancer in both cohorts. the present study is, to authors' knowledge, the largest mortality investigation conducted in Italy on electroplating workers, for both size and temporal extension. The presence of excess mortality from causes of death not consistently associated in the literature with exposure to agents in this industry suggests that further research is needed to confirm these associations.

Draft Genome Sequences of 510 Listeria monocytogenes Strains from Food Isolates and Human Listeriosis Cases from Northern Italy.

PubMed

Lomonaco, Sara; Gallina, Silvia; Filipello, Virginia; Sanchez Leon, Maria; Kastanis, George John; Allard, Marc; Brown, Eric; Amato, Ettore; Pontello, Mirella; Decastelli, Lucia

2018-01-18

Listeriosis outbreaks are frequently multistate/multicountry outbreaks, underlining the importance of molecular typing data for several diverse and well-characterized isolates. Large-scale whole-genome sequencing studies on Listeria monocytogenes isolates from non-U.S. locations have been limited. Herein, we describe the draft genome sequences of 510 L. monocytogenes isolates from northern Italy from different sources.

Late Miocene remagnetization within the internal sector of the Northern Apennines, Italy

USGS Publications Warehouse

Aiello, I.W.; Hagstrum, J.T.; Principi, G.

2004-01-01

Paleomagnetic and geologic evidence indicates that Upper Jurassic radiolarian cherts of both the Tuscan Cherts Formation (continental margin, Tuscan Units) and the Monte Alpe Cherts Formation (oceanic crust, Ligurian Units) were remagnetized during Miocene orogenesis of the Northern Apennines of Italy. Characteristic overprint magnetizations with reversed polarities have been found over a large area within the internal sector of the Northern Apennines, including eastern Liguria, Elba Island and the Thyrrenian margin, and west of the Middle Tuscan Ridge. The reversed-polarity overprint (average direction: D=177??, I=-52??, ??95=15??) was most likely acquired during Late Miocene uplift and denudation of the orogenic chain, and thermochemical remagnetization was a probable consequence of increased circulation of orogenic fluids. Similarly, mostly reversed-polarity directions of magnetization have been found by other workers in overlying post-orogenic Messinian sediments (D=177??, I=-57??, ??95=3??), which show little counterclockwise (CCW) vertical-axis rotation with respect to stable Europe (-8??5??). The Monte Alpe Cherts sampled at sites in the external sector of the Northern Apennines, close to major tectonic features, have normal- polarity overprint directions with in situ W-SW declinations. Since the overlying post-orogenic Messinian sediments have not been substantially rotated about vertical axes, the evidence points to an earlier,pre-Late Miocene remagnetization in the external parts of the orogenic chain. ?? 2004 Elsevier B.V. All rights reserved.

Aichivirus in Children with Diarrhea in Northern Italy.

PubMed

Bergallo, Massimiliano; Galliano, Ilaria; Montanari, Paola; Rassu, Marco; Daprà, Valentina

2017-01-01

Since its discovery, Aichivirus (AiV) A has been detected, with an incidence of 0.9-4.1%, primarily when studying outbreaks of diarrhea in children or young adults. In this paper, we report the first detection of AiV in Piedmont, Italy, in pediatric patients. A total of 159 fecal specimens (from 96 males and 63 females) previously screened for rotaviruses, adenoviruses, noroviruses, human parechoviruses, saliviruses, and sapoviruses were collected from infants and children with acute gastroenteritis. The most commonly detected virus was norovirus GII (33.80%), fol lowed by rotavirus (21.30%), astrovirus (18.87%), boca virus (13.92%), sapovirus (10.90%), parechovirus (8%), norovirus GI (6.70%), adenovirus (1%), and salivirus (0.52%). Real-time polymerase chain reaction detected AiV A in 1 (0.62%) case subjects. AiV A was detected in monoinfection only in January. Our results indicate that AiV may be associated with a limited number of diarrhea cases in pediatric patients. © 2018 S. Karger AG, Basel.

Paleomagnetism and paleogeography of Jurassic radiolarian cherts from the Northern Apennines of Italy

USGS Publications Warehouse

Aiello, I.W.; Hagstrum, J.T.

2001-01-01

Oriented samples of Jurassic radiolarian chert were collected from the Tuscan domain (continental margin) and the Ligurid domain (oceanic) of the northern Apennines for paleomagnetic study to determine the paleogeographic origins of these rocks. The oceanic rocks are all thermochemically overprinted by a mostly reversed-polarity component of magnetization (B) that was likely acquired during late Miocene regional uplift of the northern Apennines. This component also dominates the lower brittle chert of the Tuscan Cherts, but disappears upsection in the more clay-rich and ductile siliceous marlstones. In addition, the Tuscan Cherts retain an inferred primary magnetization (C), isolated at temperatures between 560 and 660 degrees C, which passes a fold test and shows a polarity stratigraphy. This component indicates a paleolatitude of 11 degrees + or -4 degrees N, and a counterclockwise vertical-axis rotation of 29 degrees + or -9 degrees with respect to the southern Alps of Italy, of 49 degrees + or -8 degrees with respect to Africa, and of 91 degrees + or -8 degrees with respect to Eurasia. Our results suggest that the Tuscan domain was farther south than other deep-water continental margin sections of Adria, and that transcurrent faulting might have played a significant role in the orogenic evolution of the northern Apennines.

West Nile Virus Surveillance in 2013 via Mosquito Screening in Northern Italy and the Influence of Weather on Virus Circulation

PubMed Central

Calzolari, Mattia; Pautasso, Alessandra; Montarsi, Fabrizio; Albieri, Alessandro; Bellini, Romeo; Bonilauri, Paolo; Defilippo, Francesco; Lelli, Davide; Moreno, Ana; Chiari, Mario; Tamba, Marco; Zanoni, Mariagrazia; Varisco, Giorgio; Bertolini, Silvia; Modesto, Paola; Radaelli, Maria Cristina; Iulini, Barbara; Prearo, Marino; Ravagnan, Silvia; Cazzin, Stefania; Mulatti, Paolo; Monne, Isabella; Bonfanti, Lebana; Marangon, Stefano; Goffredo, Maria; Savini, Giovanni; Martini, Simone; Mosca, Andrea; Farioli, Marco; Gemma Brenzoni, Laura; Palei, Manlio; Russo, Francesca; Natalini, Silvano; Angelini, Paola; Casalone, Cristina; Dottori, Michele; Capelli, Gioia

2015-01-01

West Nile virus (WNV) is a recently re-emerged health problem in Europe. In Italy, an increasing number of outbreaks of West Nile disease, with occurrences of human cases, have been reported since 2008. This is particularly true in northern Italy, where entomological surveillance systems have been implemented at a regional level. The aim of this study was to use, for the first time, all the entomological data collected in the five regions undergoing surveillance for WNV in northern Italy to characterize the viral circulation (at a spatial and temporal scale), identify potential mosquito vectors, and specify relationships between virus circulation and meteorological conditions. In 2013, 286 sites covering the entire Pianura Padana area were monitored. A total of 757,461 mosquitoes were sampled. Of these, 562,079 were tested by real-time PCR in 9,268 pools, of which 180 (1.9%) were positive for WNV. The largest part of the detected WNV sequences belonged to lineage II, demonstrating that, unlike those in the past, the 2013 outbreak was mainly sustained by this WNV lineage. This surveillance also detected the Usutu virus, a WNV-related flavivirus, in 241 (2.6%) pools. The WNV surveillance systems precisely identified the area affected by the virus and detected the viral circulation approximately two weeks before the occurrence of onset of human cases. Ninety percent of the sampled mosquitoes were Culex pipiens, and 178/180 WNV-positive pools were composed of only this species, suggesting this mosquito is the main WNV vector in northern Italy. A significantly higher abundance of the vector was recorded in the WNV circulation area, which was characterized by warmer and less rainy conditions and greater evapotranspiration compared to the rest of the Pianura Padana, suggesting that areas exposed to these conditions are more suitable for WNV circulation. This observation highlights warmer and less rainy conditions as factors able to enhance WNV circulation and cause virus

West Nile Virus Surveillance in 2013 via Mosquito Screening in Northern Italy and the Influence of Weather on Virus Circulation.

PubMed

Calzolari, Mattia; Pautasso, Alessandra; Montarsi, Fabrizio; Albieri, Alessandro; Bellini, Romeo; Bonilauri, Paolo; Defilippo, Francesco; Lelli, Davide; Moreno, Ana; Chiari, Mario; Tamba, Marco; Zanoni, Mariagrazia; Varisco, Giorgio; Bertolini, Silvia; Modesto, Paola; Radaelli, Maria Cristina; Iulini, Barbara; Prearo, Marino; Ravagnan, Silvia; Cazzin, Stefania; Mulatti, Paolo; Monne, Isabella; Bonfanti, Lebana; Marangon, Stefano; Goffredo, Maria; Savini, Giovanni; Martini, Simone; Mosca, Andrea; Farioli, Marco; Gemma Brenzoni, Laura; Palei, Manlio; Russo, Francesca; Natalini, Silvano; Angelini, Paola; Casalone, Cristina; Dottori, Michele; Capelli, Gioia

2015-01-01

West Nile virus (WNV) is a recently re-emerged health problem in Europe. In Italy, an increasing number of outbreaks of West Nile disease, with occurrences of human cases, have been reported since 2008. This is particularly true in northern Italy, where entomological surveillance systems have been implemented at a regional level. The aim of this study was to use, for the first time, all the entomological data collected in the five regions undergoing surveillance for WNV in northern Italy to characterize the viral circulation (at a spatial and temporal scale), identify potential mosquito vectors, and specify relationships between virus circulation and meteorological conditions. In 2013, 286 sites covering the entire Pianura Padana area were monitored. A total of 757,461 mosquitoes were sampled. Of these, 562,079 were tested by real-time PCR in 9,268 pools, of which 180 (1.9%) were positive for WNV. The largest part of the detected WNV sequences belonged to lineage II, demonstrating that, unlike those in the past, the 2013 outbreak was mainly sustained by this WNV lineage. This surveillance also detected the Usutu virus, a WNV-related flavivirus, in 241 (2.6%) pools. The WNV surveillance systems precisely identified the area affected by the virus and detected the viral circulation approximately two weeks before the occurrence of onset of human cases. Ninety percent of the sampled mosquitoes were Culex pipiens, and 178/180 WNV-positive pools were composed of only this species, suggesting this mosquito is the main WNV vector in northern Italy. A significantly higher abundance of the vector was recorded in the WNV circulation area, which was characterized by warmer and less rainy conditions and greater evapotranspiration compared to the rest of the Pianura Padana, suggesting that areas exposed to these conditions are more suitable for WNV circulation. This observation highlights warmer and less rainy conditions as factors able to enhance WNV circulation and cause virus

Estimating the real incidence of invasive listeriosis through an integrated surveillance model in use in Lombardy (Italy, 2006-2014).

PubMed

Zolin, A; Amato, E; D'Auria, M; Gori, M; Huedo, P; Bossi, A; Pontello, M

2017-07-01

The annual incidence of listeriosis in Italy is lower (0·19-0·27 per 100 000 inhabitants per year) than in Europe (0·34-0·52 per 100 000 inhabitants per year). Since the observed incidence of listeriosis may be biased downward for underdiagnosis or under-reporting, this work aims to estimate the real incidence of listeriosis during a 9-year period in the Lombardy region, Italy. Data on listeriosis cases were collected from national mandatory notification system (MAINF) and Laboratory-based Surveillance System (LabSS). The two sources were cross-matched and capture-recapture method was applied to estimate the number of undetected cases and the real incidence of invasive listeriosis. Five hundred and eighty invasive listeriosis cases were detected by the two sources between 2006 and 2014: 50·2% were identified only via MAINF, 16·7% were recorded only via LabSS, overlaps occurred in 192 cases (33·1%). The mean annual incidence detected only by MAINF was 0·56 per 100 000 inhabitants, which rose to 0·67 per 100 000 considering also the cases detected by LabSS. The capture-recapture method allowed to estimate an incidence of 0·84 per 100 000. The high incidence of listeriosis may be due to improved sensitivity of the surveillance system, but also reflect a real increase, associated with an increased population at risk.

Incidence of tonsillar cancer in northern Sweden: Impact of human papilloma virus.

PubMed

Loizou, Christos; Laurell, Göran; Lindquist, David; Öfverman, Charlotte; Stefansson, Kristina; Nylander, Karin; Olofsson, Katarina

2015-12-01

The incidence rate of tonsillar cancer is increasing worldwide. The current study identifies a parallel increase in the incidence of tonsillar cancer, human papilloma virus (HPV) and p16 expression among a population from northern Sweden, a sparsely populated area, confirming the strong association between p16 and HPV infection in tonsillar tissue. Data from the Swedish Cancer Registry was assessed to identify cases of tonsillar cancer in the northern territorial area of Sweden. HPV DNA was extracted from paraffin embedded diagnostic biopsies and detected by polymerase chain reaction using general primers Gp5+/6+ and CpI/IIG. Expression of p16 was identified by immunochemistry. Patients were grouped into urban or rural residence categories. A total of 214 cases were identified, comprising 155 (72.4%) men and 59 (27.6%) women, and 65 of these patients, who presented between 2000 and 2012, were analyzed. The overall median age for the analyzed patients was 58 years; 48 (74%) were males (median age, 57.5 years) and 17 (26%) were females (median age, 65 years). Of the 65 specimens, 59 (91%) were positive for HPV, and 62 (95%) expressed p16. The incidence of tonsillar cancer in the cohort demonstrated a 2-fold increase between 1990 and 2013; specifically, a 2.7-fold increase was observed in men whilst the female group exhibited only a small increase. These findings demonstrate a strong association between p16 expression and HPV infection in tonsillar malignancies. The incidence of HPV-positive tonsillar cancer has increased in recent years, even in sparsely populated regions, as demonstrated in northern Sweden.

Seasonal monitoring and estimation of regional aerosol distribution over Po valley, northern Italy, using a high-resolution MAIAC product

NASA Astrophysics Data System (ADS)

Arvani, Barbara; Pierce, R. Bradley; Lyapustin, Alexei I.; Wang, Yujie; Ghermandi, Grazia; Teggi, Sergio

2016-09-01

In this work, the new 1 km-resolved Multi-Angle Implementation of Atmospheric Correction (MAIAC) algorithm is employed to characterize seasonal PM10 - AOD correlations over northern Italy. The accuracy of the new dataset is assessed compared to the widely used Moderate Resolution Imaging Spectroradiometer (MODIS) Collection 5.1 Aerosol Optical Depth (AOD) data, retrieved at 0.55 μm with spatial resolution of 10 km (MYD04_L2). We focused on evaluating the ability of these two products to characterize both temporal and spatial distributions of aerosols within urban and suburban areas. Ground PM10 measurements were obtained from 73 of the Italian Regional Agency for Environmental Protection (ARPA) monitoring stations, spread across northern Italy, during a three-year period from 2010 to 2012. The Po Valley area (northern Italy) was chosen as the study domain because of its severe urban air pollution, resulting from it having the highest population and industrial manufacturing density in the country, being located in a valley where two surrounding mountain chains favor the stagnation of pollutants. We found that the global correlations between the bin-averaged PM10 and AOD are R2 = 0.83 and R2 = 0.44 for MYD04_L2 and for MAIAC, respectively, suggesting a greater sensitivity of the high-resolution product to small-scale deviations. However, the introduction of Relative Humidity (RH) and Planetary Boundary Layer (PBL) depth corrections allowed for a significant improvement to the bin-averaged PM - AOD correlation, which led to a similar performance: R2 = 0.96 for MODIS and R2 = 0.95 for MAIAC. Furthermore, the introduction of the PBL information in the corrected AOD values was found to be crucial in order to capture the clear seasonal cycle shown by measured PM10 values. The study allowed us to define four seasonal linear correlations that estimate PM10 concentrations satisfactorily from the remotely sensed MAIAC AOD retrieval. Overall, the results show that the high

Seasonal Monitoring and Estimation of Regional Aerosol Distribution over Po Valley, Northern Italy, Using a High-Resolution MAIAC Product

NASA Technical Reports Server (NTRS)

Arvani, Barbara; Pierce, R. Bradley; Lyapustin, Alexei I.; Wang, Yujie; Ghermandi, Grazia; Teggi, Sergio

2016-01-01

In this work, the new 1-km-resolved Multi-Angle Implementation of Atmospheric Correction (MAIAC) algorithm is employed to characterize seasonal AOD-PM10 correlations over northern Italy. The accuracy of the new dataset is assessed versus the widely used Moderate Resolution Imaging Spectroradiometer (MODIS) Collection 5.1 Aerosol Optical Depth (AOD) data, retrieved at 0.55 microns with spatial resolution of 10 km (MYD04). We focused on evaluating the ability of these two products to characterize both temporal and spatial distributions of aerosols within urban and suburban areas. Ground PM10 measurements were obtained from 73 of the Italian Regional Agency for Environmental Protection (ARPA) monitoring stations, spread across northern Italy, for a three-year period from 2010 to 2012. The Po Valley area (northern Italy) was chosen as the study domain because of severe urban air pollution, resulting from the highest population and industrial manufacturing density in the country, being located in a valley where two surrounding mountain chains favor the stagnation of pollutants. We found that the global correlations between PM10 and AOD are R(sup 2) = 0.83 and R(sup 2) = 0.44 for MYD04_L2 and for MAIAC, respectively, suggesting for a greater sensitiveness of the high-resolution product to small-scale deviations. However, the introduction of Relative Humidity (RH) and Planetary Boundary Layer (PBL) depth corrections gave a significant improvement to the PM AOD correlation, which led to similar performance: R(sup 2) = 0.96 for MODIS and R(sup 2) = 0.95 for MAIAC. Furthermore, the introduction of the PBL information in the corrected AOD values was found to be crucial in order to capture the clear seasonal cycle shown by measured PM10 values. The study allowed us to define four seasonal linear correlations that estimate PM10 concentrations satisfactorily from the remotely sensed MAIAC AOD retrieval. Overall, the results show that the high resolution provided by MAIAC

Performance of DRAINWAT model in assessing the drainage discharge from a small watershed in the Po Valley (Northern Italy)

Treesearch

Maurizio Borin; Tomaso Bisol; Devendra M. Amatya

2010-01-01

The performance of DRAINWAT, a DRAINMOD based-watershed scale hydrology model, in predicting the water discharge was assessed in a small basin in Northern Italy during 2002-2005. DRAINWAT slightly unpredicted (4%) the total stream drainage flow respect the measured data (549 mm), in calibration (2002-04). The underprediction was 11% in 2004-05 validation period, when...

Incidence and prognosis of stroke in young adults: a population-based study in Ferrara, Italy.

PubMed

Groppo, Elisabetta; De Gennaro, Riccardo; Granieri, Gino; Fazio, Patrik; Cesnik, Edward; Granieri, Enrico; Casetta, Ilaria

2012-02-01

The reported annual incidence of juvenile stroke ranges from 9 to 47 cases per 100,000 inhabitants. We sought to estimate the incidence of first-ever stroke in young adults through a population-based stroke registry in a well-defined and stable population. We planned to collect all cases of new stroke in people aged 15-44 years in Ferrara, Italy, over the period 2002-2007. During the surveillance period, a first-ever stroke was diagnosed in 39 patients, giving a mean annual crude incidence rate of 12.1 cases per 100,000 person-years (95% CI 8.6-16.5), 9.1 when adjusted to the European population. The overall 30-day case fatality rate was 7.7, 21.4% for hemorrhagic stroke. The incidence rate was in the range of estimates detected in western countries. The case-fatality rate was lower than that reported in less recent studies. The stroke subtype predicted the probability of death and the outcome.

Surveillance of poliomyelitis in Northern Italy: Results of acute flaccid paralysis surveillance and environmental surveillance, 2012-2015.

PubMed

Pellegrinelli, Laura; Bubba, Laura; Primache, Valeria; Pariani, Elena; Battistone, Andrea; Delogu, Roberto; Fiore, Stefano; Binda, Sandro

2017-02-01

Although in the last years poliovirus (PV) transmission has been reported at the lowest levels ever recorded, the spread of virus from endemic countries endures; the high levels of immigration flows across the Mediterranean Sea jeopardize Italy for PV reintroduction. The World Health Organization (WHO) strategic plan for global poliomyelitis (polio) eradication indicates the nationwide surveillance of Acute Flaccid Paralysis (AFP) as the gold standard for detecting cases of polio. In addition, the Environmental Surveillance (ES), seeking the presence of PV and Non-Polio Enterovirus (NPEV) in sewage, is recognized as a powerful tool to confirm PV circulation in absence of AFP cases, especially in polio-free countries. Here we report the results of AFP surveillance (AFPS) and ES in Lombardy (Northern Italy) from 2012 to 2015. Forty-eight AFP cases were identified during the study period. No AFP case was caused by PV infection. NPEVs were identified in 6.3% (3/48) of AFP cases. The annual AFP incidence rate was 0.87/100'000 children <15 y in 2012, 1.42/100'000 in 2013, 1.02/100'000 in 2014, and 0.47/100'000 in 2015; according to WHO indicators, the sensitivity of AFPS was adequate in 2013 and 2014. Completeness of case investigation raised progressively during the study period to achieve the WHO standards in 2014 (92.3%) and 2015 (100%). Completeness of follow-up increased from 72.7% in 2012 to 100% in 2014. In the framework of the ES conducted in Milan, 268 wastewater samples were collected from 2012 to 2015 and no PVs were isolated. In contrast, NPEVs were detected in 65.3% (175/268) of samples. All NPEVs characterized belonged to enterovirus species B: echovirus type 11, 6 and 3 were the most frequently detected viruses, representing 29.1% (41/141), 20.6% (29/141) and 9.2% (13/141) of genotyped NPEVs, respectively. Keeping strong and encouraging both AFPS and ES is crucial to ensure that PV will not return unnoticed in Italy - as well as in other polio

The incidence and aetiology of acute pancreatitis across Europe.

PubMed

Roberts, Stephen E; Morrison-Rees, Sian; John, Ann; Williams, John G; Brown, Tim H; Samuel, David G

Acute pancreatitis is increasingly one of the most important acute gastrointestinal conditions throughout much of the world, although incidence and aetiology varies across countries and regions. This study investigated regional and national patterns in the incidence and aetiology of acute pancreatitis, demographic patterns in incidence and trends over time in incidence across Europe. A structured review of acute pancreatitis incidence and aetiology from studies of hospitalised patient case series, cohort studies or other population based studies from 1989 to 2015 and a review of trends in incidence from 1970 to 2015 across all 51 European states. The incidence of acute pancreatitis was reported from 17 countries across Europe and ranged from 4.6 to 100 per 100 000 population. Incidence was usually highest in eastern or northern Europe, although reported rates often varied according to case ascertainment criteria. Of 20 studies that reported on trends in incidence, all but three show percentage increases over time (overall median increase = 3.4% per annum; range = -0.4%-73%). The highest ratios of gallstone to alcohol aetiologies were identified in southern Europe (Greece, Turkey, Italy and Croatia) with lowest ratios mainly in eastern Europe (Latvia, Finland, Romania, Hungary, Russia and Lithuania). The incidence of acute pancreatitis varies across Europe. Gallstone is the dominant aetiology in southern Europe and alcohol in eastern Europe with intermediate ratios in northern and western Europe. Acute pancreatitis continues to increase throughout most of Europe. Copyright © 2017. Published by Elsevier B.V.

Melanoma epidemic across the millennium: time trends of cutaneous melanoma in Emilia-Romagna (Italy) from 1997 to 2004.

PubMed

Pellacani, G; Lo Scocco, G; Vinceti, M; Albertini, G; Raccagni, A Ascari; Baldassari, L; Catrani, S; Donelli, S; Ghetti, P; Lanzoni, A; Leardini, M; Reggiani, M; Santini, M; Stanganelli, I; Virgili, A; Seidenari, S

2008-02-01

After a rapid increase in malignant melanoma (MM) incidence in the last decades, trends of the melanoma epidemic in the recent years seemed not homogeneous. This study aimed at the monitoring of some epidemiological data referring to melanoma in a region of the Northern Italy during the past 8-year period. All cases of melanoma, including also in situ lesions, diagnosed in Emilia-Romagna and San Marino State, with the exclusion of Cesena province, from 1997 to 2004 were recorded and the incidence of melanoma, adjusted for the European standard population by the direct method, was calculated. Mean standardized incidence was 9.7 for invasive MMs and 11.9, considering also in situ ones, showing an ascending trend with an increment of 3.3 new incident cases in 2004 compared with 1997. No differences in age distribution, gender and site were reported. Concerning tumour thickness, although a general ascending trend in all subtypes, only thin melanoma incidence significantly increased over the study period. Contrary to data from Northern European countries, melanoma incidence still showed an ascending trend in the Italian population of Emilia Romagna.

Incidence of mesothelioma in Lombardy, Italy: exposure to asbestos, time patterns and future projections.

PubMed

Mensi, Carolina; De Matteis, Sara; Dallari, Barbara; Riboldi, Luciano; Bertazzi, Pier Alberto; Consonni, Dario

2016-09-01

In Italy, asbestos has been extensively used from 1945 to 1992. We evaluated the impact of exposure to asbestos on occurrence of malignant mesothelioma (MM) in the Lombardy Region, Northwest Italy, the most populated and industrialised Italian region. From the Lombardy Mesothelioma Registry, we selected all incident cases of MM diagnosed between 2000 and 2012. We described sources of exposure to asbestos and examined time trends of MM rates. Using Poisson age-cohort models, we derived projections of burden of MM in the Lombardy population for the period 2013-2029. In 2000-2012, we recorded 4442 cases of MM (2850 men, 1592 women). Occupational exposure to asbestos was more frequent in men (73.6%) than in women (38.2%). Non-occupational exposure was found for 13.6% of women and 3.6% of men. The average number of cases of MM per year was still increasing (+3.6% in men, +3.3% in women). Incidence rates were still increasing in individuals aged 65+ years and declining in younger people. A maximum of 417 cases of MM (267 men, 150 women) are expected in 2019. We forecast there will be 6832 more cases (4397 in men, 2435 in women) in the period 2013-2029, for a total of 11 274 cases of MM (7247 in men, 4027 in women) in 30 years. This study documented a high burden of MM in both genders in the Lombardy Region, reflecting extensive occupational (mainly in men) and non-occupational (mainly in women) exposure to asbestos in the past. Incidence rates are still increasing; a downturn in occurrence of MM is expected to occur after 2019. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

Epidemiology of granulomatosis with polyangiitis (Wegener's granulomatosis) in Northern Italy: a 15-year population-based study.

PubMed

Catanoso, Mariagrazia; Macchioni, Pierluigi; Boiardi, Luigi; Manenti, Lucio; Tumiati, Bruno; Cavazza, Alberto; Luberto, Ferdinando; Pipitone, Nicolò; Salvarani, Carlo

2014-10-01

To investigate the epidemiology of granulomatosis with polyangiitis (GPA) over a 15-year period in a defined area of northern Italy. All patients with incident GPA diagnosed from January 1, 1995 to December 31, 2009 living in the Reggio Emilia area were identified by looking at computerized hospital discharge diagnoses, by contacting Reggio Emilia Hospital physicians and community-based specialists, and by checking the databases of the pathology and the laboratory departments and the Reggio Emilia district database for rare diseases. Patients were classified according to the European Medicines Agency (EMA) algorithm. Patients were followed up from the time of diagnosis until either their death or December 31, 2011. For each case, we identified 20 control subjects from the same geographic area matched for age and gender. A total of 18 patients (7 men and 11 women) with GPA were identified. The overall age- and sex-adjusted incidence rate (IR) was 2.4 per million (95% CI: 1.2-3.5). The mean annual IR increased from 1.7/million/year during 1995-1999 to 3.4 during 2005-2009. The highest IR occurred in females aged 70-79 years (13.5 per million; 95% CI: 5.0-30.0) and in males aged ≥ 80 years (14.9 per million; 95% CI: 2.5-49.4). The prevalence of GPA on December 31, 2009 was 34.3 per million (95% CI: 20.3-54.2). The point prevalence per million increased from 17.8 (95% CI: 7.7-35.1) in 1999 to 34.3 (95% CI: 20.3-54.2) in 2009. Survival among individuals with GPA was significantly reduced compared to that observed in the matched control population (p < 0.001). In the Italian population, GPA is very uncommon and GPA patients have reduced survival. Copyright © 2014 Elsevier Inc. All rights reserved.

Surveillance of poliomyelitis in Northern Italy: Results of acute flaccid paralysis surveillance and environmental surveillance, 2012–2015

PubMed Central

Pellegrinelli, Laura; Bubba, Laura; Primache, Valeria; Pariani, Elena; Battistone, Andrea; Delogu, Roberto; Fiore, Stefano; Binda, Sandro

2017-01-01

ABSTRACT Although in the last years poliovirus (PV) transmission has been reported at the lowest levels ever recorded, the spread of virus from endemic countries endures; the high levels of immigration flows across the Mediterranean Sea jeopardize Italy for PV reintroduction. The World Health Organization (WHO) strategic plan for global poliomyelitis (polio) eradication indicates the nationwide surveillance of Acute Flaccid Paralysis (AFP) as the gold standard for detecting cases of polio. In addition, the Environmental Surveillance (ES), seeking the presence of PV and Non-Polio Enterovirus (NPEV) in sewage, is recognized as a powerful tool to confirm PV circulation in absence of AFP cases, especially in polio-free countries. Here we report the results of AFP surveillance (AFPS) and ES in Lombardy (Northern Italy) from 2012 to 2015. Forty-eight AFP cases were identified during the study period. No AFP case was caused by PV infection. NPEVs were identified in 6.3% (3/48) of AFP cases. The annual AFP incidence rate was 0.87/100′000 children <15 y in 2012, 1.42/100′000 in 2013, 1.02/100′000 in 2014, and 0.47/100′000 in 2015; according to WHO indicators, the sensitivity of AFPS was adequate in 2013 and 2014. Completeness of case investigation raised progressively during the study period to achieve the WHO standards in 2014 (92.3%) and 2015 (100%). Completeness of follow-up increased from 72.7% in 2012 to 100% in 2014. In the framework of the ES conducted in Milan, 268 wastewater samples were collected from 2012 to 2015 and no PVs were isolated. In contrast, NPEVs were detected in 65.3% (175/268) of samples. All NPEVs characterized belonged to enterovirus species B: echovirus type 11, 6 and 3 were the most frequently detected viruses, representing 29.1% (41/141), 20.6% (29/141) and 9.2% (13/141) of genotyped NPEVs, respectively. Keeping strong and encouraging both AFPS and ES is crucial to ensure that PV will not return unnoticed in Italy - as well as in other

High Rates of Mycobacterium tuberculosis among Socially Marginalized Immigrants in Low-Incidence Area, 1991–2010, Italy

PubMed Central

Mercadante, Silvio; Pareek, Manish; Lalvani, Ajit; Bugiani, Massimiliano

2013-01-01

Migration from low- and middle-income countries to high-income countries increasingly determines the severity of tuberculosis (TB) cases in the adopted country. Socially marginalized groups, about whom little is known, may account for a reservoir of TB among the immigrant populations. We investigated the rates of and risk factors for Mycobacterium tuberculosis transmission, infection, and disease in a cohort of 27,358 socially marginalized immigrants who were systematically screened (1991–2010) in an area of Italy with low TB incidence. Overall TB and latent TB infection prevalence and annual tuberculin skin testing conversion rates (i.e., incidence of new infection) were 2.7%, 34.6%, and 1.7%, respectively. Prevalence of both TB and latent TB infection and incidence of infection increased as a function of the estimated TB incidence in the immigrants’ countries of origin. Annual infection incidence decreased with time elapsed since immigration. These findings have implications for control policy and immigrant screening in countries with a low prevalence of TB. PMID:23965807

Incidence of smear-positive tuberculosis in Dabat, northern Ethiopia.

PubMed

Tadesse, T; Demissie, M; Berhane, Y; Kebede, Y; Abebe, M

2013-05-01

To determine the incidence of smear-positive tuberculosis (TB) in Dabat District, northern Ethiopia. Using a population-based longitudinal design, a TB surveillance system was initiated among 46,165 residents at the Dabat Health and Demographic Surveillance System site. Trained field workers visited each household every third month and interviewed all individuals aged ≥14 years using a uniform questionnaire to detect suspected cases of TB (cough ≥15 days), at which time two sputum (spot-morning) samples were collected for smear microscopy. A total of 281,820 person-months were observed during the 1-year period, which generated 74 smear-positive TB cases. The incidence of smear-positive TB was calculated at 311 per 100,000 person-years (95%CI 240-382). Higher rates were observed among females (incidence rate ratio [IRR] 2.08, 95%CI 1.24-3.52), persons with no schooling (IRR 2.74, 95%CI 1.11-6.78) and urban residents (IRR 2.39, 95%CI 1.39-4.12). The incidence of smear-positive TB is high in Dabat District, suggesting a high risk of transmission in the communities. TB control programmes thus need to improve case-finding mechanisms at the community level in Ethiopia, with greater emphasis on risk groups.

The epidemiology of amyotrophic lateral sclerosis in Reggio Emilia, Italy.

PubMed

Bonvicini, Francesca; Vinceti, Marco; Marcello, Norina; Rodolfi, Rossella; Rinaldi, Manuela

2008-12-01

Incidence and mortality rates of amyotrophic lateral sclerosis (ALS) vary between countries, and in some studies appear to increase over time. We performed a study to assess ALS incidence in a northern Italy area over a 10-year period. We identified the new cases of probable or definite ALS diagnosed among residents in Reggio Emilia province between 1996 and 2005 using several sources of data, such as death certificates, clinical records, hospital discharge registers and drug prescriptions. A total of 94 newly-diagnosed patients were identified. The average standardized incidence in the period was 2.0 and 1.0 cases/100,000/year, using the Italian and the world population, respectively, as reference. There was no variation in rates over time. Incidence was 1.3 in males and 0.8 in females. No cases were observed in patients under 35 years of age. Incidence increased after the age of 55 years, reaching a peak in the group aged 70-74 years and declining thereafter. We concluded that ALS incidence in this population was similar to that observed in other Italian regions and European countries, and no variation was identified during the study period.

Observed linkages between the northern annular mode/North Atlantic Oscillation, cloud incidence, and cloud radiative forcing

NASA Astrophysics Data System (ADS)

Li, Ying; Thompson, David W. J.; Huang, Yi; Zhang, Minghong

2014-03-01

The signature of the northern annular mode/North Atlantic Oscillation (NAM/NAO) in the vertical and horizontal distribution of tropospheric cloudiness is investigated in CloudSat and CALIPSO data from June 2006 to April 2011. During the Northern Hemisphere winter, the positive polarity of the NAM/NAO is marked by increases in zonally averaged cloud incidence north of ~60°N, decreases between ~25 and 50°N, and increases in the subtropics. The tripolar-like anomalies in cloud incidence associated with the NAM/NAO are largest over the North Atlantic Ocean basin/Middle East and are physically consistent with the NAM/NAO-related anomalies in vertical motion. Importantly, the NAM/NAO-related anomalies in tropospheric cloud incidence lead to significant top of atmosphere cloud radiative forcing anomalies that are comparable in amplitude to those associated with the NAM/NAO-related temperature anomalies. The results provide observational evidence that the most prominent pattern of Northern Hemisphere climate variability is significantly linked to variations in cloud radiative forcing. Implications for two-way feedback between extratropical dynamics and cloud radiative forcing are discussed.

Active transpression in the northern Calabria Apennines, southern Italy

NASA Astrophysics Data System (ADS)

Ferranti, L.; Santoro, E.; Mazzella, M. E.; Monaco, C.; Morelli, D.

2009-10-01

the Amendolara ridge and northern Sila, where partitioning between thrust and left strike-slip motion occurs in response to ˜ E to ˜ NE directed shortening. A local ˜ NW-SE extension is recorded by fault-kinematic analysis on NE-SW striking fault segments parallel to the coast on the eastern flank of Pollino. These small-length normal faults do not form a through-going lineament, rather they accommodate the seaward collapse of the uppermost crust above the deeper shortening compartment. Conversely, the active transpression testified by geomorphic, structural and seismicity data is accommodated along deep-seated oblique back-thrusts that involve the Apulian foreland plate underlying the now inactive thin-skinned accretionary wedge down to near-Moho depths. In light of the tight interlacing between regional and local components of deformation affecting the marine terraces, we suggest that the large-scale uplift in this sector of Calabria may reflect whole crustal-scale folding. The novel seismotectonic frame reconstructed for this region is consistent with GPS velocities suggesting that large part of geodetic shortening detected between the Apennines and the Apulian block on the eastern side of southern Italy might be accommodated in northern Calabria.

Swine vesicular disease in northern Italy: diffusion through densely populated pig areas.

PubMed

Bellini, S; Alborali, L; Zanardi, G; Bonazza, V; Brocchi, E

2010-12-01

At the end of 2006, a recrudescence of swine vesicular disease (SVD) was recorded in Italy and the disease spread widely throughout the northern regions. Lombardy, a densely populated pig area, was most affected and the presence of the disease caused heavy economic losses to the entire pig industry. Although SVD is considered only moderately contagious, the epidemic in the north was characterised by a rapid spread of the condition. Numerous difficulties were encountered in eradicating it. Over the past decade, there has been a significant increase in the population of pigs in Lombardy, concentrated mainly in a few areas which were the most severely affected during the 2006 to 2007 SVD epidemic. Increases in both the pig population and animal movements, combined with weak biosecurity measures, increased the spread rate of the disease and hampered eradication activities.

Provenance and accommodation pathways of late Quaternary sediments in the deep-water northern Ionian Basin, southern Italy

NASA Astrophysics Data System (ADS)

Perri, Francesco; Critelli, Salvatore; Dominici, Rocco; Muto, Francesco; Tripodi, Vincenzo; Ceramicola, Silvia

2012-12-01

The northern Calabria along the southeastern coast of Italy provides a favorable setting in which to study complete transects from continental to deep-marine environments. The present northern Ionian Calabrian Basin is a wedge-top basin within the modern foreland-basin system of southern Italy. The Ionian margin of northern Calabria consists of a moderately developed fluvial systems, the Crati and Neto rivers, and diverse smaller coastal drainages draining both the Calabria continental block (i.e., Sila Massif) and the southern Apennines thrust belt (i.e., Pollino Massif). The main-channel sand of the Crati and Neto rivers is quartzofeldspathic with abundant metamorphic and plutonic lithic fragments (granodiorite, granite, gneiss, phyllite and sedimentary lithic fragments). Sedimentary lithic fragments were derived from Jurassic sedimentary successions of the Longobucco Group. The mud samples contain mostly phyllosilicates, quartz, calcite, feldspars and dolomite. Traces of gypsum are present in some samples. The I-S mixed layers, 10 Å-minerals (illite and micas), chlorite and kaolinite are the most abundant phyllosilicates, whereas smectite and chlorite/smectite mixed layers are in small amounts. The geochemical signatures of the muds reflect a provenance characterized by both felsic and mafic rocks with a significant input from carbonate rocks. Furthermore, the degree of source-area weathering was most probably of low intensity rather than moderately intense because CIA values for the studied mud samples are low. Extrapolation of the mean erosion budget from 1 to 25 Ma suggests that at least 5 to 8 km of crust have been removed from the Calabrian orogenic belt and deposited in the marine basins. The Calabrian microplate played an important role in the dynamic evolution of southern Italian fossil and modern basins, representing the key tectonic element of the entire orogenic belt.

Adolescents in southern regions of Italy adhere to the Mediterranean diet more than those in the northern regions.

PubMed

Noale, Marianna; Nardi, Mariateresa; Limongi, Federica; Siviero, Paola; Caregaro, Lorenza; Crepaldi, Gaetano; Maggi, Stefania

2014-09-01

There is a large amount of literature regarding the benefits of the Mediterranean diet in the adult population; however, there is growing curiosity about the individuals who naturally adhere to those principles early in life. The "Evaluation of Dietary Habits in Adolescents," carried out by the National Research Council of Italy in 2009, is a survey that aimed to assess the dietary habits and lifestyles of Italian adolescents and their adherence to the Mediterranean diet. We hypothesized that there would be differences across regions, with a higher adherence in Southern Italy compared with Northern Italy based on geography. The survey was conducted in 3 different geographic locations in Italy and included a convenience sample of adolescents who attended either a middle or high school. The participants were asked to fill out a questionnaire concerning demographic data, lifestyle factors, and eating patterns, and scores were assigned according to adherence to the Mediterranean diet, as calculated using Trichopoulou's Mediterranean diet scale. The final sample included 565 adolescents, between 12 and 19 years old, who attended school in the northeastern, northwestern, or southern regions of Italy in 2009. According to the findings, 38.6% of the respondents had scores indicating a low adherence to the Mediterranean diet, whereas only 14% had scores showing a high adherence. Teenagers from the Southern region showed the highest adherence. Those with a high adherence to the Mediterranean diet consumed higher quantities of fiber, iron, vitamin B6, vitamin C, folic acid, vitamin A, vitamin D, and monounsaturated fats. Copyright © 2014 Elsevier Inc. All rights reserved.

Breast Cancer in Lampang, a Province in Northern Thailand: Analysis of 1993-2012 Incidence Data and Future Trends.

PubMed

Lalitwongsa, Somkiat; Pongnikorn, Donsuk; Daoprasert, Karnchana; Sriplung, Hutcha; Bilheem, Surichai

2015-01-01

The recent epidemiologic transition in Thailand, with decreasing incidence of infectious diseases along with increasing rates of chronic conditions, including cancer, is a serious problem for the country. Breast cancer has the highest incidence rates among females throughout Thailand. Lampang is a province in the upper part of Northern Thailand. A study was needed to identify the current burden, and the future trends of breast cancer in upper Northern Thai women. Here we used cancer incidence data from the Lampang Cancer Registry to characterize and analyze the local incidence of breast cancer. Joinpoint analysis, age period cohort model and Nordpred package were used to investigate the incidences of breast cancer in the province from 1993 to 2012 and to project future trends from 2013 to 2030. Age-standardized incidence rates (world) of breast cancer in the upper parts of Northern Thailand increased from 16.7 to 26.3 cases per 100,000 female population which is equivalent to an annual percentage change of 2.0-2.8%, according to the method used. Linear drift effects played a role in shaping the increase of incidence. The three projection method suggested that incidence rates would continue to increase in the future with incidence for women aged 50 and above, increasing at a higher rate than for women below the age of 50. The current early detection measures increase detection rates of early disease. Preparation of a budget for treatment facilities and human resources, both in surgical and medical oncology, is essential.

Fungal biodiversity in the periglacial soil of Dosdè Glacier (Valtellina, Northern Italy).

PubMed

Rodolfi, Marinella; Longa, Claudia Maria Oliveira; Pertot, Ilaria; Tosi, Solveig; Savino, Elena; Guglielminetti, Maria; Altobelli, Elisa; Del Frate, Giuseppe; Picco, Anna Maria

2016-03-01

Periglacial areas are one of the least studied habitats on Earth, especially in terms of their fungal communities. In this work, both molecular and culture-dependent methods have been used to analyse the microfungi in soils sampled on the front of the East Dosdè Glacier (Valtellina, Northern Italy). Although this survey revealed a community that was rich in fungal species, a distinct group of psychrophilic microfungi has not been detected. Most of the isolated microfungi were mesophiles, which are well adapted to the sensitive climatic changes that occur in this alpine environment. A discrepancy in the results that were obtained by means of the two diagnostic approaches suggests that the used molecular methods cannot entirely replace traditional culture-dependent methods, and vice versa. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Habitat management of organic vineyard in Northern Italy: the role of cover plants management on arthropod functional biodiversity.

PubMed

Burgio, G; Marchesini, E; Reggiani, N; Montepaone, G; Schiatti, P; Sommaggio, D

2016-12-01

The effect of cover plants on arthropod functional biodiversity was investigated in a vineyard in Northern Italy, through a 3-year field experiment. The following six ground cover plants were tested: Sweet Alyssum; Phacelia; Buckwheat; Faba Bean; Vetch and Oat; control. Arthropods were sampled using different techniques, including collection of leaves, vacuum sampling and sweeping net. Ground cover plant management significantly affected arthropod fauna, including beneficial groups providing ecosystem services like biological control against pests. Many beneficial groups were attracted by ground cover treatments in comparison with control, showing an aggregative numerical response in the plots managed with some of the selected plant species. Alyssum, Buckwheat and 'Vetch and Oat' mixture showed attractiveness on some Hymenoptera parasitoid families, which represented 72.3% of the insects collected by sweeping net and 45.7 by vacuum sampling. Phytoseiidae mites showed a significant increase on leaves of the vineyard plots managed with ground covers, in comparison with control, although they did not show any difference among the treatments. In general, the tested ground cover treatments did not increase dangerous Homoptera populations in comparison with control, with the exception of Alyssum. The potential of ground cover plant management in Italian vineyards is discussed: the overall lack of potential negative effects of the plants tested, combined with an aggregative numerical response for many beneficials, seems to show a potential for their use in Northern Italy vineyards.

Going green? Ex-post valuation of a multipurpose water infrastructure in Northern Italy.

PubMed

Reynaud, Arnaud; Lanzanova, Denis; Liquete, Camino; Grizzetti, Bruna

2017-10-01

A contingent valuation approach is used to estimate how households value different multipurpose infrastructures (conventional or green) for managing flood risk and water pollution. As a case study we consider the Gorla Maggiore water park located in the Lombardy Region, in Northern Italy. The park is a neo-ecosystem including an infrastructure to treat waste water and store excess rain water, built in 2011 on the shore of the Olona River in an area previously used for poplar plantation. This park is the first one of this type built in Italy. A novel aspect of our research is that it not only considers the values people hold for different water ecosystem services (pollution removal, recreative use, wildlife support, flood risk reduction), but also their preferences for how those outcomes are achieved (through conventional or green infrastructures). The results indicate that the type of infrastructure delivering the ecosystem services does have an impact on individuals' preferences for freshwater ecosystem services. Households are willing to pay from 6.3 to 7.1 euros per year for a green infrastructure (compared to a conventional one), with a premium up to 16.5 euros for a surrounding made of a park. By considering the type of infrastructure within the choice model, we gain a richer understanding of the relationship between social welfare and freshwater ecosystem services.

Increased incidence of renal parenchymal carcinoma in the Northern and Yorkshire region of England, 1978-1997.

PubMed

Tate, R; Iddenden, R; Harnden, P; Morris, E; Craigs, C; Bennett, C; Brook, C; Haward, R A; Forman, D

2003-05-01

Kidney cancer remains relatively rare, but incidence and mortality rates are reported to be rising steadily across the world. To determine if such increases were occurring in the UK, we examined the rates of incidence and mortality in different histological subtypes of kidney cancer in the Northern and Yorkshire region of England. Details of all 8741 cases diagnosed between 1978 and 1997 were extracted from the population-based Northern and Yorkshire Cancer Registry. For all types of tumour, both incidence and mortality rates increased over the study period. Overall age-standardised incidence rates increased by 86% for renal parenchymal carcinoma (RPC) (80% for males, 90% for females) from 2.8 to 5.2 cases per 100000 (3.8-6.8 male, 2.0-3.8 female). There were incidence increases in all age groups, all Carstairs index groups and in both urban and rural populations. Although increased incidental detection of kidney tumours by improved investigational techniques may account for some of this rise, we believe it unlikely that it accounts for all of the increase observed. Potential aetiological causes for the increased rates include hypertension, smoking, a diet lacking fruit and vegetables, analgesic use and, particularly, obesity.

Incidence of rhinitis and asthma related to welding in Northern Europe.

PubMed

Storaas, Torgeir; Zock, Jan-Paul; Morano, Ana Espinosa; Holm, Mathias; Bjørnsson, Eythor; Forsberg, Bertil; Gislason, Thorarinn; Janson, Christer; Norback, Dan; Omenaas, Ernst; Schlünssen, Vivi; Torén, Kjell; Svanes, Cecilie

2015-11-01

Welding-related asthma is well recognised but less is known about rhinitis in relation to welding. The aim here, was to study associations between welding, rhinitis and asthma in a general population sample, and factors influencing selection into and out of a welding occupation.Adult-onset asthma and non-infectious rhinitis were investigated in the international multicentre population-based Respiratory Health in Northern Europe (RHINE) study, including 16,191 responders aged 26-54 years. Ever welding (n=2181), welding >25% of working time (n=747), and welding in stainless steel >6 months (n=173) were assessed by questionnaire. Subjects with rhinitis or asthma onset when aged <18 years were excluded. Incidence rates for asthma and rhinitis were calculated from year of disease onset, and start and end of welding job. Cox's proportional hazard models adjusting for age, sex, parental education and study centre, and Kaplan-Meier curves were used.Rhinitis incidence was higher among welders (hazard ratio (HR) 1.4, 95% CI 1.3-1.6), consistent in men and women, and across centres (pheterogeneity=0.4). In men, asthma incidence was higher among welders (HR 1.4, 95% CI 1.04-1.97). Quitting welding was indicated higher after adult-onset rhinitis (HR 1.1, 95% CI 1.0-1.3). Adult-onset rhinitis and asthma was higher among welders, consistent across population samples from Northern Europe. No pre-employment selection was found, whereas selection out of welding jobs was suggested. Copyright ©ERS 2015.

A socioeconomic profile of vulnerable land to desertification in Italy.

PubMed

Salvati, Luca

2014-01-01

Climate changes, soil vulnerability, loss in biodiversity, and growing human pressure are threatening Mediterranean-type ecosystems which are increasingly considered as a desertification hotspot. In this region, land vulnerability to desertification strongly depends on the interplay between natural and anthropogenic factors. The present study proposes a multivariate exploratory analysis of the relationship between the spatial distribution of land vulnerability to desertification and the socioeconomic contexts found in three geographical divisions of Italy (north, center and south) based on statistical indicators. A total of 111 indicators describing different themes (demography, human settlements, labor market and human capital, rural development, income and wealth) were used to discriminate vulnerable from non-vulnerable areas. The resulting socioeconomic profile of vulnerable areas in northern and southern Italy diverged significantly, the importance of demographic and economic indicators being higher in southern Italy than in northern Italy. On the contrary, human settlement indicators were found more important to discriminate vulnerable and non-vulnerable areas in northern Italy, suggesting a role for peri-urbanization in shaping the future vulnerable areas. An in-depth knowledge of the socioeconomic characteristics of vulnerable land may contribute to scenarios' modeling and the development of more effective policies to combat desertification. © 2013 Elsevier B.V. All rights reserved.

Update on the epidemiology of tuberculosis in Italy.

PubMed

Conversano, Michele

2014-05-01

As in many countries in Western Europe, in Italy tuberculosis (TB) is a relatively rare disease. In the last decade its incidence has remained constant at under 10 cases/100,000 inhabitants, the threshold considered to define a country as low prevalence. The epidemiological picture, however, is very different in the countries of Eastern Europe and in Africa, Asia, and Latin America, where the incidence of TB continues to increase and in some cases is accompanied by the emergence and spread of multidrug-resistant TB. The present review describes the epidemiology of TB in Italy. In 2008, the incidence rate was 3.8 cases per 100,000 for people born in Italy, and 50-60 cases per 100,000 for those born abroad. There was an increase in cases from Eastern Europe. The crude mortality rate for TB in 2006 was 0.7 deaths per 100,000 residents. Although TB is a low-prevalence disease in Italy, its epidemiology is changing. Since 1955, more than 160,000 people in Italy have died from this potentially preventable and curable disease.

Slope Stability Analysis In Seismic Areas Of The Northern Apennines (Italy)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lo Presti, D.; Fontana, T.; Marchetti, D.

2008-07-08

Several research works have been published on the slope stability in the northern Tuscany (central Italy) and particularly in the seismic areas of Garfagnana and Lunigiana (Lucca and Massa-Carrara districts), aimed at analysing the slope stability under static and dynamic conditions and mapping the landslide hazard. In addition, in situ and laboratory investigations are available for the study area, thanks to the activities undertaken by the Tuscany Seismic Survey. Based on such a huge information the co-seismic stability of few ideal slope profiles have been analysed by means of Limit equilibrium method LEM - (pseudo-static) and Newmark sliding block analysismore » (pseudo-dynamic). The analysis--results gave indications about the most appropriate seismic coefficient to be used in pseudo-static analysis after establishing allowable permanent displacement. Such indications are commented in the light of the Italian and European prescriptions for seismic stability analysis with pseudo-static approach. The stability conditions, obtained from the previous analyses, could be used to define microzonation criteria for the study area.« less

Aseismic Deformation Associated with an Earthquake Swarm in the Northern Apennines (Italy)

NASA Astrophysics Data System (ADS)

Gualandi, A.; Nichele, C.; Serpelloni, E.; Chiaraluce, L.; Anderlini, L.; Latorre, D.; Belardinelli, M. E.; Avouac, J. P.

2017-12-01

Analyzing the displacement time series from continuous GPS (cGPS) with an Independent Component Analysis (ICA) we detect a transient deformation signal that correlates both in space and time with a seismic swarm activity (maximum Mw = 3.69 ± 0.09) occurred in the hanging wall of the Altotiberina normal fault (Northern Apennines, Italy) in 2013-2014. The geodetic transient lasted ˜6 months and produced a NW-SE trending extension of ˜ 5.3 mm, consistent with the regional tectonic regime. The seismicity and the geodetic signal are consistent with slip on two splay faults in the ATF hanging wall. Comparing the seismic moment associated with the geodetic transient and the seismic events, we observe that seismicity accounts for only a fraction of the measured geodetic deformation. The combined seismic and aseismic slip decreased the Coulomb stress on the locked shallow portion of the ATF, while the transition region to the creeping section has been loaded.

Ethical issues of prison nursing: A qualitative study in Northern Italy.

PubMed

Sasso, Loredana; Delogu, Barbara; Carrozzino, Roberto; Aleo, Giuseppe; Bagnasco, Annamaria

2018-05-01

Prisons are contexts where nurses are required to have specific skills to ensure that, in a setting designed for the expiation of crime, prisoners receive the same type of care as anyone else. But this is not always the case, giving rise to ethical issues. 'How do correctional nurses describe their working experience in prisons? What issues emerged?' This is a qualitative descriptive study. Following purposive sampling, we conducted five focus groups. Thematic analysis was used to analyse the data. Participants and research context: Our sample included 31 correctional nurses in seven prisons in Northern Italy. Ethical considerations: The scientific merit of this study was recognized by the Academic Board of the University of Genoa. Approval to conduct the study was obtained from the Liguria Regional Government that funded this study and from the Local Health Authority that was the prison nurses' employer. Formal consent was obtained from all the nurses who volunteered to participate in this study. Five themes emerged from the focus groups: (1) prisoners' healthcare needs, (2) negotiation between custody and care, (3) satisfaction of working in prisons, (4) obstacles to quality care and (5) safety. 'Manipulation' was a transversal theme that emerged from all the focus groups. The problems generated by the clash between prison security and nursing care priorities did not enable nurses to practice autonomously and provide the best possible to care prisoners, giving rise to ethical issues and moral distress. This in turn causes high nursing turnover rates that negatively impact continuum of care. In Italy, correctional nurses urgently require specific education interventions with the participation of all those who work in prisons. Interventions based on the post-modern concept of restorative nursing could offer prison nurses the opportunity to both resolve ethical issues and reduce moral distress.

Key factors influencing lung cancer survival in northern Italy.

PubMed

Mangone, Lucia; Minicozzi, Pamela; Vicentini, Massimo; Giacomin, Adriano; Caldarella, Adele; Cirilli, Claudia; Falcini, Fabio; Giorgi Rossi, Paolo; Sant, Milena

2013-06-01

Lung cancer is a major cause of cancer death worldwide. The aims of this study were to analyze presentation, treatment and survival for lung cancer in northern Italy, and identify factors influencing survival. A total of 1180 lung cancer cases diagnosed in four north Italian cancer registries (Biella, Modena, Reggio Emilia, Romagna) in 2003-2005 were analyzed. Information on morphology, stage, diagnostic examinations, chemotherapy, radiotherapy, and surgical treatment was collected from clinical records. Three-year relative survival and relative excess risks of death were estimated. Overall, 10% of cases were stage I, 50% stage IV, and 12% stage unknown. Romagna - where sophisticated diagnostic examinations were performed more often - had proportionately more microscopically verified cases and resected cases than Biella. Romagna had also high proportions of cases given chemotherapy and radiotherapy. Three-year survival was 14%, range 10% (Biella) to 19% (Romagna); 69% for stage I, 3% for stage IV. Stage I survival was higher in Romagna (82%) than Reggio Emilia and Biella (60-61%) but for operated stage I cases, survival was similar (88%) in Romagna and Biella. The fully adjusted model showed a higher risk of death in Biella (1.23, 95%CI 1.02-1.48) than Modena (reference). Stage and surgery are key factors influencing survival. Centralizing lung cancer treatment to improve diagnostic work-up may improve outcomes. Copyright © 2013 Elsevier Ltd. All rights reserved.

Impact of socioeconomic status and district of residence on cutaneous malignant melanoma prognosis: a survival study on incident cases between 1991 and 2011 in the province of Ferrara, northern Italy.

PubMed

Borghi, Alessandro; Corazza, Monica; Virgili, Annarosa; Lambertini, Anna G; Caranci, Nicola; Pacelli, Barbara; Carcoforo, Paolo; Ferretti, Stefano

2017-12-01

The aim of this study was to analyse the impact of socioeconomic status (SES) on the prognosis of patients with invasive malignant melanoma (MM) incident from 1991 to 2011 in the province of Ferrara, northern Italy. A total of 750 patients provided by the Area Vasta Emilia Centrale Cancer Registry were included in this retrospective cohort study. Prognosis was analysed in terms of overall survival and specific survival. The study determinants were the patients' SES and district of residence. The confounding effect of sex, age, period and TNM stage at diagnosis was evaluated. In the study population, neither overall survival nor specific survival showed significant differences among different layers of SES and districts of residence. The risk for death from MM was lower for the female sex [hazard risk (HR)=0.68, 95% confidence interval (CI): 0.50-0.94] and for diagnoses made in the most recent period (2005-2011: HR=0.56, 95% CI: 0.36-0.89 with respect to 1991-1997). A worse prognosis was observed in patients older than 70 years at the time of diagnosis (HR=2.33, 95% CI: 1.39-3.91 with respect to the <40-year age group) and in patients with more than pT1 tumours (up to 20 times for pT4 tumours). SES and district of residence did not constitute prognostic factors for MM patients residing in the province of Ferrara. Homogeneity in MM staging, treatment and follow-up strategies due to the relatively small extent of the study area and the presence of a single university hospital of reference, as well as less marked social and economic differences among the study patients in comparison with other previously analysed populations, may account for this finding.

Incidence of rheumatoid arthritis, psoriatic arthritis and polymyalgia rheumatica in an inland area of central Italy: results of the CAMPO-RHE study.

PubMed

De Socio, Antonia; Perrotta, Fabio Massimo; Grasso, Guido Maria; Lubrano, Ennio

2018-01-01

The aim of the CAMPO-RHE study was to determine the incidence of rheumatoid arthritis (RA), psoriatic arthritis (PsA) and polymyalgia rheumatica (PMR) in patients attending a rheumatologic outpatient's clinic of a new institution in Campobasso, Italy. Campobasso is a small town of approximately 50,000 inhabitants located in the inland territory of central Italy (Molise), and Public Health is managed from a single health authority. In Italy, all citizens are registered with a National Health System of General Practitioner (GP) Physicians. Between the 1 st of June 2014 and the 31 st of May 2016, all consecutive adult patients, sent by a GP, of Campobasso with any diagnosis of musculoskeletal symptoms/signs/complaints were evaluated in a single rheumatology outpatient clinic of our Academic Unit. The clinic represents the first and unique reference for GPs about rheumatic diseases in the territory. Subjects were classified using the 2010 EULAR criteria for RA, the CASPAR criteria for PsA and the 2012 ACR classification criteria for PMR. 1003 adult patients, sent by GPs, with articular or musculoskeletal complaints visited our clinic. Of these, 409 inhabitants of the municipality of Campobasso were evaluated for the study. During the 2-year study period we diagnosed 18, 19 and 12 new cases of RA, PsA and PMR respectively, with a new incident cases rate of 21.4, 22.59 and 27.43/100,000/year on the population at risk. The results of our study could contribute to better define the incidence of these rheumatic diseases classified with the new classification criteria.

The 2012 Emilia (Northern Italy) earthquake sequence: an attempt of historical reading

NASA Astrophysics Data System (ADS)

Graziani, L.; Bernardini, F.; Castellano, C.; Del Mese, S.; Ercolani, E.; Rossi, A.; Tertulliani, A.; Vecchi, M.

2015-04-01

In May-June 2012, the Po Valley (Northern Italy) was struck by an earthquake sequence whose strongest event occurred on 20 May (Mw 5.9). The intensity values (Imax 7-8 EMS98) assessed through macroseismic field surveys seemed inappropriate to describe the whole range of effects observed, especially those to monumental heritage, which suffered very heavy damage and destruction. The observed intensities in fact were significantly lower than those we could have expected after a Mw 5.9 event for Italy. As magnitude-intensity regressions are mainly based on historical earthquake data, we handle this issue going back in time and debating the following hypotheses: (a) the 2012 Emilia earthquake sequence shows lower intensity values than expected because the affected urban context is more heterogeneous and much less vulnerable than that in the past; (b) some historical earthquakes, especially those that occurred centuries ago and are provided with little information, could show a tendency to be overestimated in intensity, and consequently in magnitude. In order to give consistency to such hypotheses, we have introduced, as a test, a dual historical reading of the 2012 Emilia earthquake sequence as if it had occurred in the past: the first reading refers to a period prior to the introduction of concrete in buildings assessing the intensity on traditional masonry buildings only. A further historical reading, assessed by using information on monumental buildings only, was performed, and it can be roughly referred to the XVI-XVII centuries. In both cases, intensity values tend to grow significantly. The results could have a relevant impact when considered for seismic hazard assessments if confirmed on a large scale.

Estimate of population coverage with the prostate specific antigen (PSA) test to screen for prostate cancer in a metropolitan area of northern Italy.

PubMed

Russo, A; Autelitano, M; Bellini, A; Bisanti, L

2002-01-01

The use of the prostate specific antigen (PSA) test in the period 1999-2000 in a population of 311 822 men, aged 40 years or more, resident in Milan, Italy, was examined. Data were drawn from the outpatient database of the local health information system. A total of 139 350 PSA tests were used in 83 943 subjects. Overall, 26.9% of the male population aged 40 or older, with no history of prostate cancer, received a PSA test in the 2 year study period. For subjects older than 50 the rate rose to 34%. Results show a high coverage of the male population in northern Italy with screening using the PSA test for prostate cancer.

The burden of rare cancers in Italy: the surveillance of rare cancers in Italy (RITA) project.

PubMed

Trama, Annalisa; Mallone, Sandra; Ferretti, Stefano; Meduri, Francesca; Capocaccia, Riccardo; Gatta, Gemma

2012-01-01

The project Surveillance of rare cancers in Italy (RITA) provides, for the first time, estimates of the burden of rare cancers in Italy based on the list of rare cancers proposed in collaboration with the European project Surveillance of Rare Cancers in Europe (RARECARE). RITA analyzed data from Italian population-based cancer registries (CR). The period of diagnosis was 1988 to 2002, and vital status information was available up to December 31, 2003. Incidence rates were estimated for the period 1995-2002, survival for the years 2000-2002 (with the period method of Brenner), and complete prevalence at January 1, 2003. Rare cancers are those with an incidence <6/100,000/year. In Italy, every year there are 60,000 new diagnoses of rare cancers corresponding to 15% of all new cancer diagnoses. Five-year relative survival was on the average worse for rare cancers (53%) than for common cancers (73%). A total of 770,000 patients were living in Italy in 2008 with a diagnosis of a rare cancer, 22% of the total cancer prevalence. Our estimates constitute a useful base for further research and support the idea that rare cancers are a public health problem that deserves attention. Centers of expertise for rare cancers that pool cases, expertise and resources could ensure an adequate clinical management for these diseases. Our data also showed that cancer registries are suitable sources of data to estimate incidence, prevalence and survival for rare cancers and should continue to monitoring rare cancers in Italy.

Homicide-suicide in Brescia County (Northern Italy): a retrospective study from 1987 to 2012.

PubMed

Verzeletti, Andrea; Russo, Maria Cristina; De Ferrari, Francesco

2014-07-01

From January 1987 to December 2012, 19 homicide-suicide events were registered at the Brescia Institute of Forensic Medicine (Northern Italy), leading to 39 deaths (20 homicide victims and 19 suicide victims). The homicide victims were females in the total of the cases (100%), while perpetrators were exclusively males (100%). Only one event involved foreigners as both victim and perpetrator, all the other cases regarded Italian people. The average age was 37.3 years for the homicide victims and 41.57 years for the offenders. Perpetrators usually used a firearm both for murder (65%) and suicide (84%). In 66% of the cases the homicide-suicide events occurred at home; homicide victims were strictly bound to their perpetrators (husband, boyfriend or ex boyfriend, father) in all the events. Copyright © 2014 Elsevier Ltd and Faculty of Forensic and Legal Medicine. All rights reserved.

Helicobacteraceae in Bulk Tank Milk of Dairy Herds from Northern Italy

PubMed Central

Bianchini, Valentina; Recordati, Camilla; Borella, Laura; Gualdi, Valentina; Scanziani, Eugenio; Selvatico, Elisa; Luini, Mario

2015-01-01

Helicobacter pylori is responsible for gastritis and gastric adenocarcinoma in humans, but the routes of transmission of this bacterium have not been clearly defined. Few studies led to supposing that H. pylori could be transmitted through raw milk, and no one investigated the presence of other Helicobacteraceae in milk. In the current work, the presence of Helicobacteraceae was investigated in the bulk tank milk of dairy cattle herds located in northern Italy both by direct plating onto H. pylori selective medium and by screening PCR for Helicobacteraceae, followed by specific PCRs for H. pylori, Wolinella spp., and “Candidatus Helicobacter bovis.” Three out of 163 bulk milk samples tested positive for Helicobacteraceae, but not for the subsequent PCRs. H. pylori was not isolated in any case. However, given similar growth conditions, Arcobacter butzleri, A. cryaerophilus, and A. skirrowii were recovered. In conclusion, the prevalence of Helicobacteraceae in raw milk was negligible (1.8%), and H. pylori was not identified in any of the positive samples, suggesting that, at least in the farming conditions of the investigated area, bovine milk does not represent a potential source of infection. PMID:26090429

Prevalence and incidence of external genital warts in a sample of Italian general female population.

PubMed

Suligoi, Barbara; Vittori, Giorgio; Salfa, Maria Cristina; Timelli, Laura; Corsini, Dario; Fattorini, Giovanni; Mariani, Luciano

2017-02-06

The Human papillomavirus is the most common sexually transmitted virus worldwide. The objective of this study was to estimate: 1) the prevalence and the incidence of external genital warts (eGW) in a sample of women attending community outpatient clinics and 2) the total number of eGW cases in the Italian female population aged 15-64 years. A prospective study was performed for a 12-month period between 2009 and 2010, among a sample of women attending community gynecological outpatient clinics located throughout Italy. Demographic data, for every woman aged 15-64 years, were collected. For women diagnosed with eGW, behavioral and clinical data were recorded. Prevalence of eGW was calculated as the proportion between the number of women with eGW and that of women visiting any of the participating gynecologists; incidence of eGW was calculated as the proportion between the number of women with a new diagnosis of eGW and that of women visiting any of the participating gynecologists. Standardized prevalence by age was used to estimate the number of eGW cases occurring in the Italian female population aged 15-64 years. In 2009-2010, 44 community gynecologists were included in the network. In one-year period, 16,410 women visited any of the participating gynecologists; 63 women were diagnosed with eGW, corresponding to a prevalence of 3.8 cases per 1,000 women per year (95%CI: 2.9-4.9). The incidence of eGW was 3.0 cases per 1,000 women per year (95%CI: 2.2-3.9). Women aged 15-24 years showed both the highest prevalence and incidence. Prevalence and incidence significantly decreased by increasing age group (p <0.001), and were higher in Southern Italy compared to Central-Northern Italy. The estimated number of women with eGW among women aged 15-64 years in Italy, in 2010, was approximately 69,000. These data show a high prevalence and incidence of eGW among young women in Italy, stress the effectiveness of community clinical networks in investigating STI epidemiology

Inverse association between dietary vitamin D and risk of cutaneous melanoma in a northern Italy population

PubMed Central

Vinceti, Marco; Malagoli, Carlotta; Fiorentini, Chiara; Longo, Caterina; Crespi, Catherine M.; Albertini, Giuseppe; Ricci, Cinzia; Lanzoni, Anna; Reggiani, Maurizio; Virgili, Annarosa; Osti, Federica; Lombardi, Mara; Santini, Marcello; Fanti, Pier Alessandro; Dika, Emi; Sieri, Sabina; Krogh, Vittorio; Seidenari, Stefania; Pellacani, Giovanni

2010-01-01

The possibility of an inverse association between vitamin D and risk of cancer and, in particular, of cutaneous malignant melanoma has been suggested, but results of epidemiologic studies are still conflicting. We examined the relation between dietary vitamin D intake and melanoma risk through a population-based case-control study (380 cases, 719 controls) in a northern region of Italy, a country with average vitamin D intake lower than in northern Europe or the US. We assessed average daily intake of vitamin D from foodstuffs using the European Prospective Investigation into Cancer and Nutrition (EPIC) semiquantitative food frequency questionnaire. In this population, levels of vitamin D intake were considerably lower than those observed in recent US studies. We found an inverse relation between dietary vitamin D and melanoma risk in the sample as a whole, in both crude and adjusted analyses. In sex and age-specific analyses, this association appeared to be stronger among males and among older subjects. These findings suggest that, at the relatively low levels of intake observed in this sample, an inverse relation between dietary vitamin D and risk of cutaneous malignant melanoma may exist. PMID:21541899

[Pleural mesothelioma mortality in Italy: time series reconstruction (1970-2009) and comparison with incidence (2003-2008)].

PubMed

Ferrante, Pierpaolo; Mastrantonio, Marina; Uccelli, Raffaella; Corfiati, Marisa; Marinaccio, Alessandro

2016-01-01

the large amount of asbestos used in many Countries (including Italy) is causing an epidemic of asbestos related diseases, which is still ongoing because of their long latency. this study is aimed at reconstructing Italian time series of deaths for mesothelioma in the period 1970-2009 and comparing Italian incidence and mortality data. deaths for pleural cancer (1970-2003,2006-2009) and mesothelioma (2003, 2006-2009) were recorded by the Italian Institute of Statistics (Istat) and provided by the Italian National Agency for New Technologies, Energy and the Environment (ENEA), incidence cases (1993-2008) were provided by the Italian mesotheliomas register (ReNaM) at the Italian National Workers' Compensation Authority (Inail). For the period before ICD-10 implementation (1970-2002) and when Istat data (2004-2005) are lacking, mesothelioma deaths were estimated through statistical models (logistic, Poisson). National incidence and mortality data were compared during the overlapping period (2003, 2006-2008). the mortality curve strongly rises from 1970 and seems to be smoothed in the last years. Mortality caused by mesothelioma and incident cases with certain diagnosis are overlapping, as are mortality due to pleural cancer other than mesothelioma and mesothelioma incidence with uncertain diagnosis (probable/possible). this epidemiological analysis of deaths encoded as pleural tumour suggests to carefully investigate space-temporal distribution before excluding they could be mesotheliomas. Some new lights have been thrown on the statistical behaviour of mesothelioma mortality.

A foetal tile from an archaeological site: anthropological investigation of human remains recovered in a medieval cemetery in Northern Italy.

PubMed

Licata, Marta; Rossetti, Chiara; Tosi, Adelaide; Badino, Paola

2018-06-01

The recovery of foetal remains is very sporadic in archaeology, especially due the scarce degree of bone mineralisation. This paper presents the singular archaeological discovery of a foetal tile preserving the bone remains, object of our anthropological examination. The foetal tile was discovered during an archaeological excavation in a medieval site (Northern Italy). The tile was analysed by CT scan and later, human remains were anthropologically examined. The archaeological investigation revealed a special ritual destined to foetuses while forensic anthropological analysis allowed estimating the gestational age near to 21-24 weeks.

Bladder cancer and occupation: a case-control study in northern Italy.

PubMed Central

Porru, S; Aulenti, V; Donato, F; Boffetta, P; Fazioli, R; Cosciani Cunico, S; Alessio, L

1996-01-01

OBJECTIVES--A hospital based case-control study was conducted between 1992 and 1993 in the province of Brescia, a highly industrialised area in northern Italy, to evaluate occupational risk factors of bladder cancer. METHODS--The study evaluated 355 histologically confirmed cases of bladder cancer (275 men, 80 women) and 579 controls affected by urological non-neoplastic diseases (397 men, 182 women). Lifetime occupational history, smoking and drinking habits, and sociodemographic characteristics were recorded by means of a structured questionnaire. Odds ratios (ORs) were computed with adjustment for age, smoking, alcohol and coffee consumption, education, and place of residence. RESULTS--A significant (P < 0.05) increase of risk of bladder cancer were found in men for labourers in the construction industry (OR 2.1, 95% confidence interval (95% CI) 1.1-3.9) and for recreational and cultural services (OR 5.0, 95% CI 1.3-18.9). Increased risks, although not significant, were found for various other occupations and industries such as machinery mechanics, metal processers and polishers, blacksmiths, gunsmiths, painters; for transport workers, an increased risk with increasing duration of employment was found. CONCLUSIONS--Occupational exposures seem to contribute to bladder cancer risk in the area under study. PMID:8563860

Occupation and lung cancer in two industrialized areas of northern Italy.

PubMed

Ronco, G; Ciccone, G; Mirabelli, D; Troia, B; Vineis, P

1988-03-15

A population-based case-control study on lung cancer was conducted in 2 industrialized areas of northern Italy. Cases (126) were all males who died from lung cancer between 1976 and 1980. Controls (384) were a random sample of males dying from other causes during the same period. Jobs held during working life have been analyzed according to a list of occupations already known to be causally associated with lung cancer (list A) and a list of occupations suspected of being so (list B). Attributable risk percentages in the population for occupations included in either list A or B were about 36% and 12% in the 2 areas. Welders or workers in industries in which welding is common showed elevated odds ratios: 2.9 for welders (95% CI 0.9-9.8); 4.9 (1.1-22.9) for structural metal workers; 11.4 (2.6-49.9) for workers in structural metal production. Other job categories associated with lung cancer included: electricians and workers in electrical machine production, woodworkers (in furniture or cabinet making, but not in carpentry or joinery) and cleaning services. Smoking did not seem to exert a substantial confounding effect. Attributable risk percentages for tobacco smoking were about 78% and 76% in the population of the 2 areas.

Diabetes and risk of cancer incidence: results from a population-based cohort study in northern Italy.

PubMed

Ballotari, Paola; Vicentini, Massimo; Manicardi, Valeria; Gallo, Marco; Chiatamone Ranieri, Sofia; Greci, Marina; Giorgi Rossi, Paolo

2017-10-25

Aim of this study was to compare cancer incidence in populations with and without diabetes by cancer site. Furthermore, we aimed at comparing excess risk of cancer according to diabetes type, diabetes duration and treatment, the latter as regards Type 2 diabetes. By use of the Reggio Emilia diabetes registry we classified the resident population aged 20-84 at December 31 st 2009 into two groups: with and without diabetes. By linking with the cancer registry we calculated the 2010-2013 cancer incidence in both groups. The incidence rate ratios (IRR) by cancer site, type of diabetes, diabetes duration, and as concerns Type 2 diabetes, by treatment regimen were computed using Poisson regression model and non-diabetic group as reference. The cohort included 383,799 subjects without diabetes and 23,358 with diabetes. During follow-up, we identified 1464 cancer cases in subjects with diabetes and 9858 in the remaining population. Overall cancer incidence was higher in subjects with diabetes than in those without diabetes (IRR = 1.22, 95%CI 1.15-1.29), with similar results focusing on subjects with at least 2-year diabetes duration. Cancer sites driving overall increased risk were liver, pancreas, Colon rectum, and bladder in both sexes, corpus uteri for females. There was also suggestion of an increased risk for kidney cancer in females and a decreased risk for prostate cancer. Excess risk was found in patients with Type 2 diabetes, more marked among insulin users, especially with combined therapy. We observed an increasing risk for diabetes duration up to 10 years from diagnosis (IRR = 1.44, 95%CI 1.29-1.61) and a subsequent decrease to moderate-higher risk (IRR = 1.15, 95%CI 1.04-1.30). Our study indicates that the strength of association depends on specific cancer site. Insulin, monotherapy or combined therapy, per se or as an indication of poor blood glucose control, in addition to diabetes duration, may play a role in the association of diabetes and

Serological and molecular tools to diagnose visceral leishmaniasis: 2-years’ experience of a single center in Northern Italy

PubMed Central

Ortalli, Margherita; Attard, Luciano; Vanino, Elisa; Gaibani, Paolo; Vocale, Caterina; Rossini, Giada; Cagarelli, Roberto; Pierro, Anna; Billi, Patrizia; Mastroianni, Antonio; Di Cesare, Simona; Codeluppi, Mauro; Franceschini, Erica; Melchionda, Fraia; Gramiccia, Marina; Scalone, Aldo; Gentilomi, Giovanna A.; Landini, Maria P.

2017-01-01

The diagnosis of visceral leishmaniasis (VL) remains challenging, due to the limited sensitivity of microscopy, the poor performance of serological methods in immunocompromised patients and the lack of standardization of molecular tests. The aim of this study was to implement a combined diagnostic workflow by integrating serological and molecular tests with standardized clinical criteria. Between July 2013 and June 2015, the proposed workflow was applied to specimens obtained from 94 in-patients with clinical suspicion of VL in the Emilia-Romagna region, Northern Italy. Serological tests and molecular techniques were employed. Twenty-one adult patients (22%) had a confirmed diagnosis of VL by clinical criteria, serology and/or real-time polymerase chain reaction; 4 of these patients were HIV-positive. Molecular tests exhibited higher sensitivity than serological tests for the diagnosis of VL. In our experience, the rK39 immunochromatographic test was insufficiently sensitive for use as a screening test for the diagnosis of VL caused by L. infantum in Italy. However, as molecular tests are yet not standardized, further studies are required to identify an optimal screening test for Mediterranean VL. PMID:28832646

Mortality of Talc Miners and Millers From Val Chisone, Northern Italy: An Updated Cohort Study.

PubMed

Pira, Enrico; Coggiola, Maurizio; Ciocan, Catalina; Romano, Canzio; La Vecchia, Carlo; Pelucchi, Claudio; Boffetta, Paolo

2017-07-01

The aim of this study was to update the analysis of mortality of a cohort of talc miners and millers in Northern Italy. We analyzed the mortality during 1946 to 2013 of 1722 male workers in an asbestos-free talc mine (1166 miners and 556 millers) employed during 1946 to 1995. The overall standardized mortality ratio (SMR) was 1.24 [95% confidence interval (95% CI) 1.17 to 1.32]; no deaths were observed from pleural cancer; mortality from lung cancer was not increased. Mortality from pneumoconiosis was increased (SMR 26.62; 95% CI 20.71 to 33.69), in particular among miners, and was associated with duration of employment and time since first employment. We confirmed the lack of association between exposure to asbestos-free talc, lung cancer, and mesothelioma. Increased mortality from pneumoconiosis among miners is attributable to past exposure to silica.

Landslide early warning based on failure forecast models: the example of Mt. de La Saxe rockslide, northern Italy

NASA Astrophysics Data System (ADS)

Manconi, A.; Giordan, D.

2015-02-01

We investigate the use of landslide failure forecast models by exploiting near-real-time monitoring data. Starting from the inverse velocity theory, we analyze landslide surface displacements on different temporal windows, and apply straightforward statistical methods to obtain confidence intervals on the estimated time of failure. Here we describe the main concepts of our method, and show an example of application to a real emergency scenario, the La Saxe rockslide, Aosta Valley region, northern Italy. Based on the herein presented case study, we identify operational thresholds based on the reliability of the forecast models, in order to support the management of early warning systems in the most critical phases of the landslide emergency.

Recent and active tectonics of the external zone of the Northern Apennines (Italy)

NASA Astrophysics Data System (ADS)

Boccaletti, Mario; Corti, Giacomo; Martelli, Luca

2011-08-01

We present a comprehensive study of the recent and active tectonics of the external part of the Northern Apennines (Italy) by using morphotectonic, geological-structural, and stratigraphic analysis, compared with the current seismicity of the region. This analysis suggests that the external part of the Northern Apennines is characterised by presence of three major systems of Quaternary compressive structures corresponding to (1) the Apenninic watershed, (2) the Apennines-Po Plain margin (pede-Apenninic thrust front), and (3) the Emilia, Ferrara, and Adriatic Fold systems buried below the Po Plain. Geological data and interpreted seismic sections indicate a roughly N-S Quaternary deformation direction, with rates <2.5 mm/year. The shortening decreased since the Pliocene, when our data indicate compression in a NNW-SSE direction and rates up to 7 mm/year. The trend and kinematics of the structures affecting the Apennines-Po Plain margin and the Po Plain subsoil fit well the pattern of the current seismicity of the area, as well as recent GPS and geodetic levelling data, pointing to a current activity of these thrust systems controlled by an overall compressive stress field. Close to the Apenninic watershed, earthquake focal mechanisms indicate that shallow extension is associated to deep compression. The extensional events may be related to a secondary extensional stress field developing on the hangingwall of the thrust system affecting the Apenninic watershed; alternatively, this thrust system may have been recently deactivated and overprinted by active normal faulting. Deeper compressive events are related to the activity of both a major basement thrust that connects at surface with the pede-Apenninic thrust front and a major Moho structure.

The Seismotectonics of the Po Plain (Northern Italy): Tectonic Diversity in a Blind Faulting Domain

NASA Astrophysics Data System (ADS)

Vannoli, Paola; Burrato, Pierfrancesco; Valensise, Gianluca

2015-05-01

We present a systematic and updated overview of a seismotectonic model for the Po Plain (northern Italy). This flat and apparently quiet tectonic domain is, in fact, rather active as it comprises the shortened foreland and foredeep of both the Southern Alps and the Northern Apennines. Assessing its seismic hazard is crucial due to the concentration of population, industrial activities, and critical infrastructures, but it is also complicated because (a) the region is geologically very diverse, and (b) nearly all potential seismogenic faults are buried beneath a thick blanket of Pliocene-Pleistocene sediments, and thus can be investigated only indirectly. Identifying and parameterizing the potential seismogenic faults of the Po Plain requires proper consideration of their depth, geometry, kinematics, earthquake potential and location with respect to the two confronting orogens. To this end, we subdivided them into four main, homogeneous groups. Over the past 15 years we developed new strategies for coping with this diversity, resorting to different data and modeling approaches as required by each individual fault group. The most significant faults occur beneath the thrust fronts of the Ferrara-Romagna and Emilia arcs, which correspond to the most advanced and buried portions of the Northern Apennines and were the locus of the destructive May 2012 earthquake sequence. The largest known Po Plain earthquake, however, occurred on an elusive reactivated fault cutting the Alpine foreland south of Verona. Significant earthquakes are expected to be generated also by a set of transverse structures segmenting the thrust system, and by the deeper ramps of the Apennines thrusts. The new dataset is intended to be included in the next version of the Database of Individual Seismogenic Sources (DISS; http://diss.rm.ingv.it/diss/, version 3.2.0, developed and maintained by INGV) to improve completeness of potential sources for seismic hazard assessment.

Contribution of lifetime smoking habit in France and Northern Ireland to country and socioeconomic differentials in mortality and cardiovascular incidence: the PRIME Study.

PubMed

Yarnell, J W G; Patterson, C C; Arveiler, D; Amouyel, P; Ferrières, J; Woodside, J V; Haas, B; Montaye, M; Ruidavets, J B; Kee, F; Evans, A; Bingham, A; Ducimetière, P

2012-07-01

This study examines the contribution of lifetime smoking habit to the socioeconomic gradient in all-cause and smoking-related mortality and in cardiovascular incidence in two countries. 10,600 men aged 50-59 years were examined in 1991-4 in centres in Northern Ireland and France and followed annually for 10 years. Deaths and cardiovascular events were documented. Current smoking habit, lifetime smoking (pack-years) and other health behaviours were evaluated at baseline. As socio-occupational coding schemes differ between the countries seven proxy socioeconomic indicators were used. Lifetime smoking habit showed marked associations with most socioeconomic indicators in both countries, but lifetime smoking was more than 10 pack-years greater overall in Northern Ireland and smoking patterns differed. Total mortality was 49% higher in Northern Ireland than in France, and smoking-related mortality and cardiovascular incidence were 93% and 92% higher, respectively. Both lifetime smoking and fibrinogen contributed independently to these differentials, but together explained only 42% of the difference in total mortality between countries, adjusted for both biological and lifestyle confounders. Socioeconomic gradients were steeper for total and smoking-related mortality than for cardiovascular incidence. Residual contributions of lifetime smoking habit ranged from 6% to 34% for the seven proxy indicators of socioeconomic position for total and smoking-related mortality. Socioeconomic gradients in cardiovascular incidence were minimal following adjustment for confounders. In Northern Ireland and France lifetime smoking appeared to explain a significant part of the gradients in total and smoking-related mortality between socioeconomic groups, but the contribution of smoking was generally small for cardiovascular incidence.

The incidence of cytomegalovirus (CMV) antigenemia and CMV disease is reduced by highly active antiretroviral therapy.

PubMed

Varani, S; Spezzacatena, P; Manfredi, R; Chiodo, F; Mastroianni, A; Ballarini, P; Boschini, A; Lazzarotto, T; Landini, M P

2000-05-01

Cytomegalovirus (CMV) infection was one of the most common opportunistic infections in AIDS patients, leading to blindness or life-threatening disease in about 40% of patients in the later stages of AIDS before highly active antiretroviral therapy (HAART). In a retrospective multicenter study we investigated the incidence of CMV retinitis and organ involvement in Northern Italy before (1995 and 1996) and after the introduction of HAART (1997 and 1998) as well as the data regarding CMV antigenemia. We found a sharp drop in the incidence of CMV disease in AIDS patients as well as a decline in the incidence of relapses of CMV-disease after the widespread introduction of HAART. Moreover, there was a decrease in the incidence of antigenemia-positive cases in AIDS patients in the era of HAART and the median CMV viral load was significantly higher in patients who didn't receive HAART than in patients who received HAART (p = 0.001, t test).

Oak forest exploitation and black-locust invasion caused severe shifts in epiphytic lichen communities in Northern Italy.

PubMed

Nascimbene, Juri; Marini, Lorenzo

2010-10-15

In the last two centuries, native European oak forests have undergone a dramatic decline related to increasing human pressure for agriculture and urbanization. Oak forests were either completely eradicated and transformed into agricultural landscapes or replaced by second-growth formations. Intensive forest management and the replacement of native forests with production forests or arable lands are recognized amongst the main threats to many lichens in Europe. In this study, we used historical information on the epiphytic lichen biota which was hosted in a native oak-dominated forest of Northern Italy to identify shifts of lichen communities due to the changes in land use which occurred during the last two centuries. We also compared the epiphytic lichen communities inhabiting remnant oak forests with those found in the habitats that have replaced native forests: black-locust forests and agrarian landscapes. Almost all the species sampled during the 19th century are now extinct. The loss of native habitat and the subsequent invasion by black locust were probably the most influential factors which affected the composition of lichen communities, causing the local extinction of most of the species historically recorded. Despite the fact that oak remnants host only a few species which were historically recorded, and that they currently are the lichen poorest habitat in the study region, they host lichen assemblages differing from those of black-locust forests and agrarian stands. In these habitats lichen assemblages are mainly composed of species adapted to well-lit, dry conditions and tolerating air pollution and eutrophication. This pattern is likely to be common also in other lowland and hilly regions throughout Northern Italy where oak forests are targeted among the habitats of conservation concern at the European level. For this reason, a national strategy for biodiversity conservation and monitoring of lowlands forests should provide the framework for local

The shallow boreholes at The AltotiBerina near fault Observatory (TABOO; northern Apennines of Italy)

NASA Astrophysics Data System (ADS)

Chiaraluce, L.; Collettini, C.; Cattaneo, M.; Monachesi, G.

2014-04-01

As part of an interdisciplinary research project, funded by the European Research Council and addressing the mechanics of weak faults, we drilled three 200-250 m-deep boreholes and installed an array of seismometers. The array augments TABOO (The AltotiBerina near fault ObservatOry), a scientific infrastructure managed by the Italian National Institute of Geophysics and Volcanology. The observatory, which consists of a geophysical network equipped with multi-sensor stations, is located in the northern Apennines (Italy) and monitors a large and active low-angle normal fault. The drilling operations started at the end of 2011 and were completed by July 2012. We instrumented the boreholes with three-component short-period (2 Hz) passive instruments at different depths. The seismometers are now fully operational and collecting waveforms characterised by a very high signal to noise ratio that is ideal for studying microearthquakes. The resulting increase in the detection capability of the seismic network will allow for a broader range of transients to be identified.

Facies-related fracturing in turbidites: insights from the Marnoso-Arenacea Fm. (Northern Apennines, Italy)

NASA Astrophysics Data System (ADS)

Ogata, Kei; Storti, Fabrizio; Balsamo, Fabrizio; Bedogni, Enrico; Tinterri, Roberto; Fetter, Marcos; Gomes, Leonardo; Hatushika, Raphael

2016-04-01

Natural fractures deeply influence subsurface fluid flow, exerting a primary control on resources like aquifers, hydrocarbons and geothermal reservoirs, and on environmental issues like CO2 storage and nuclear waste disposal. In layered sedimentary rocks, depositional processes-imprinted rock rheology favours the development of both mechanical anisotropy and heterogeneity on a wide range of scales, and are thus expected to strongly influence location and frequency of fractures. To better constrain the contribution of stratigraphic, sedimentological and petrophysical attributes, we performed a high-resolution, multidisciplinary study on a selected stratigraphic interval of jointed foredeep turbidites in the Miocene Marnoso-arenacea Formation (Northern Apennines, Italy), which are characterised by a great lateral and vertical variability of grain-size and depositional structures. Statistical relationships among field and laboratory data significantly improve when the single facies scale is considered, and, for similar facies recording different evolutionary stages of the parent turbidity currents, we observed a direct correlation between the three-dimensional anisotropies of rock hardness tensors and the normalized fracture frequencies, testifying for the primary sedimentary flow-related control on fracture distributions.

Electrical resistivity tomography for studying liquefaction induced by the May 2012 Emilia-Romagna earthquake (Mw = 6.1, northern Italy)

NASA Astrophysics Data System (ADS)

Giocoli, A.; Quadrio, B.; Bellanova, J.; Lapenna, V.; Piscitelli, S.

2014-04-01

This work shows the result of an electrical resistivity tomography (ERT) survey carried out for imaging and characterizing the shallow subsurface affected by the coseismic effects of the Mw = 6.1 Emilia-Romagna (northern Italy) earthquake that occurred on 20 May 2012. The most characteristic coseismic effects were ground failure, lateral spreading and liquefaction that occurred extensively along the paleo-Reno River in the urban areas of San Carlo and Mirabello (southwestern portion of Ferrara Province). In total, six electrical resistivity tomographies were performed and calibrated with surface geological surveys, exploratory boreholes and aerial photo interpretations. This was one of first applications of the electrical resistivity tomography method in investigating coseismic liquefaction.

Deciphering the relative weights of demographic transition and vaccination in the decrease of measles incidence in Italy.

PubMed

Merler, Stefano; Ajelli, Marco

2014-02-22

In Italy, during the course of the past century to the present-day, measles incidence underwent a remarkable decreasing trend that started well before the introduction of the national immunization programme. In this work, we aim at examining to what extent both the demographic transition, characterized by declining mortality and fertility rates over time, and the vaccination programme are responsible for the observed epidemiological pattern. Making use of a non-stationary, age-structured disease transmission model, we show that in the pre-vaccination era, from 1901 to 1982, the decline in birth rates has resulted in a drastic decrease in the effective transmission rate, which in turn has determined a declining trend of measles incidence (from 25.2 to 10.3 infections per 1000 individuals). However, since 1983, vaccination appears to have become the major contributing factor in the decrease of measles incidence, which otherwise would have remained stable as a consequence of the nearly constant birth rates. This led to a remarkable decrease in the effective transmission rate, to a level well below the critical threshold for disease persistence. These findings call for the adoption of epidemiological models, which deviate the age structure from stationary equilibrium solutions, to better understand the biology of infectious diseases and evaluate immunization programmes.

Gypsum karst in Italy: a review

NASA Astrophysics Data System (ADS)

De Waele, Jo; Chiarini, Veronica; Columbu, Andrea; D'Angeli, Ilenia M.; Madonia, Giuliana; Parise, Mario; Piccini, Leonardo; Vattano, Marco; Vigna, Bartolomeo; Zini, Luca; Forti, Paolo

2016-04-01

Although outcropping only rarely in Italy, gypsum karst has been described in detail since the early XXth century (Marinelli, 1917). Gypsum caves are now known from almost all Italian regions (Madonia & Forti, 2003), but are mainly localised along the northern border of the Apennine chain (Emilia Romagna and Marche regions), Calabria, and Sicily, where the major outcrops occur. Recently, important caves have also been discovered in the underground gypsum quarries in Piedmont (Vigna et al., 2010). During the late 80s and 90s several multidisciplinary studies have been carried out in many gypsum areas. All this work converged into a comprehensive overview in 2003 (Madonia & Forti, 2003). Further detailed studies focused on the gypsum areas of Emilia Romagna (Chiesi et al., 2010; Forti & Lucci, 2010; Demaria et al., 2012; De Waele & Pasini, 2013; Ercolani et al., 2013; Columbu et al., 2015; Lucci & Piastra, 2015; Tedeschi et al., 2015) and of Sicily (Madonia & Vattano, 2011). Sinkholes related to Permo-Triassic gypsum have been studied in Friuli Venezia Giulia (Zini et al., 2015). This presentation will review the state of the art regarding different aspects of evaporite karst in Italy focusing on the main new results. References Chiesi M., et al. (2010) - Origin and evolution of a salty gypsum/anhydrite karst spring: the case of Poiano (Northern Apennines, Italy). Hydrogeology Journal, 18, pp. 1111-1124. Columbu A. et al. (2015) - Gypsum caves as indicators of climate-driven river incision and aggradation in a rapidly uplifting region. Geology, 43(6), 539-542. Demaria D. et al. (Eds.) (2012), Le Grotte Bolognesi, GSB-USB, 431 p. De Waele J., Pasini G. (2013) - Intra-messinian gypsum palaeokarst in the northern Apennines and its palaeogeographic implications. Terra Nova 25, pp. 199-205. Ercolani M., et al. (Eds.) (2013), I Gessi e la Cave i Monte Tondo. Studio multidisciplinare di un'area carsica nella Vena del Gesso Romagnola. Memorie Ist. It. Spel. II(26), 559 p

Geographical and Cultivar Features Differentiate Grape Microbiota in Northern Italy and Spain Vineyards.

PubMed

Mezzasalma, Valerio; Sandionigi, Anna; Guzzetti, Lorenzo; Galimberti, Andrea; Grando, Maria S; Tardaguila, Javier; Labra, Massimo

2018-01-01

Recent studies have highlighted the role of the grapevine microbiome in addressing a wide panel of features, ranging from the signature of field origin to wine quality. Although the influence of cultivar and vineyard environmental conditions in shaping the grape microbiome have already been ascertained, several aspects related to this topic, deserve to be further investigated. In this study, we selected three international diffused grapevine cultivars (Cabernet Sauvignon, Syrah, and Sauvignon Blanc) at three germplasm collections characterized by different climatic conditions [Northern Italy (NI), Italian Alps (AI), and Northern Spain (NS)]. The soil and grape microbiome was characterized by 16s rRNA High Throughput Sequencing (HTS), and the obtained results showed that all grape samples shared some bacterial taxa, regardless of sampling locality (e.g., Bacillus , Methylobacterium , Sphingomonas , and other genera belonging to Alphaproteobacteria, Gammaproteobacteria, and Actinobacteria). However, some Operational Taxonomic Units (OTUs) could act as geographical signatures and in some cases as cultivar fingerprint. Concerning the origin of the grape microbiome, our study confirms that vineyard soil represents a primary reservoir for grape associated bacteria with almost 60% of genera shared between the soil and grape. At each locality, grapevine cultivars shared a core of bacterial genera belonging to the vineyard soil, as well as from other local biodiversity elements such as arthropods inhabiting or foraging in the vineyard. Finally, a machine learning analysis showed that it was possible to predict the geographical origin and cultivar of grape starting from its microbiome composition with a high accuracy (9 cases out of 12 tested samples). Overall, these findings open new perspectives for the development of more comprehensive and integrated research activities to test which environmental variables have an effective role in shaping the microbiome composition and

Social vulnerability in the flood-prone anthropogenic landscape of Northern Italy

NASA Astrophysics Data System (ADS)

Roder, Giulia; Sofia, Giulia; Wu, Zhifeng; Tarolli, Paolo

2017-04-01

The practices for reducing the impacts of floods are becoming more and more advanced, centred to the communities and reached out to vulnerable populations. Vulnerable individuals are characterised by different social and economic attributes that can alter their capacity to cope with disaster events. The Social Vulnerability Index (Cutter et al. 2003) provides an empirical basis to compare social variances in different spatial scenarios and environmental threats. This methodology has been readjusted to the flood-prone anthropogenic landscape of Northern Italy adapted to the societal and historical construction of this area. In fact, the fifteen census variables used have been contextualised by examining the economic crisis, the modification of the labour force, the gendered life expectancy, the immigration among much more. At a general consideration, the unstable economic status, the population growth, age, and ethnicity are the major social attributes affecting the residents of the floodplain. The cluster analysis performed by the calculation of univariate LISA ratifies the spatial distribution of the index (Moran's I of 0.39 showing a positive correlation) finding the main high-high clusters in the Western and the outlet of the Po River basin. This basin includes one-third of the Italian population and this anthropogenic footprint has consistently modified the basin natural and geological environment (Carminati and Martinelli 2002) to the point that the hydraulic system will be dramatically altered in the future (Dankers and Feyen 2008). The spatial identification and the inclusion of vulnerable people into the risk management planning process have been widely discussed in the Sendai Framework for Disaster Risk Reduction. For this reason, we analysed the flood risk resulting from the combination of high vulnerable areas with the highest flood hazard scenario. The hazard map, finalised in May 2015, has been provided by ISPRA Institute with a three-class flood

The ``exceptional'' earthquake of 3 January 1117 in the Verona area (northern Italy): A critical time review and detection of two lost earthquakes (lower Germany and Tuscany)

NASA Astrophysics Data System (ADS)

Guidoboni, Emanuela; Comastri, Alberto; Boschi, Enzo

2005-12-01

In the seismological literature the 3 January 1117 earthquake represents an interesting case study, both for the sheer size of the area in which that event is recorded by the monastic sources of the 12th century, and for the amount of damage mentioned. The 1117 event has been added to the earthquake catalogues of up to five European countries (Italy, France, Belgium, Switzerland, the Iberian peninsula), and it is the largest historical earthquake for northern Italy. We have analyzed the monastic time system in the 12th century and, by means of a comparative analysis of the sources, have correlated the two shocks mentioned (in the night and in the afternoon of 3 January) to territorial effects, seeking to make the overall picture reported for Europe more consistent. The connection between the linguistic indications and the localization of the effects has allowed us to shed light, with a reasonable degree of approximation, upon two previously little known earthquakes, probably generated by a sequence of events. A first earthquake in lower Germany (I0 (epicentral intensity) VII-VIII MCS (Mercalli, Cancani, Sieberg), M 6.4) preceded the far more violent one in northern Italy (Verona area) by about 12-13 hours. The second event is the one reported in the literature. We have put forward new parameters for this Veronese earthquake (I0 IX MCS, M 7.0). A third earthquake is independently recorded in the northwestern area of Tuscany (Imax VII-VIII MCS), but for the latter event the epicenter and magnitude cannot be evaluated.

Traffic-Related Air Pollution and Dementia Incidence in Northern Sweden: A Longitudinal Study

PubMed Central

Oudin, Anna; Forsberg, Bertil; Adolfsson, Annelie Nordin; Lind, Nina; Modig, Lars; Nordin, Maria; Nordin, Steven; Adolfsson, Rolf; Nilsson, Lars-Göran

2015-01-01

Background Exposure to ambient air pollution is suspected to cause cognitive effects, but a prospective cohort is needed to study exposure to air pollution at the home address and the incidence of dementia. Objectives We aimed to assess the association between long-term exposure to traffic-related air pollution and dementia incidence in a major city in northern Sweden. Methods Data on dementia incidence over a 15-year period were obtained from the longitudinal Betula study. Traffic air pollution exposure was assessed using a land-use regression model with a spatial resolution of 50 m × 50 m. Annual mean nitrogen oxide levels at the residential address of the participants at baseline (the start of follow-up) were used as markers for long-term exposure to air pollution. Results Out of 1,806 participants at baseline, 191 were diagnosed with Alzheimer’s disease during follow-up, and 111 were diagnosed with vascular dementia. Participants in the group with the highest exposure were more likely than those in the group with the lowest exposure to be diagnosed with dementia (Alzheimer’s disease or vascular dementia), with a hazard ratio (HR) of 1.43 (95% CI: 0.998, 2.05 for the highest vs. the lowest quartile). The estimates were similar for Alzheimer’s disease (HR 1.38) and vascular dementia (HR 1.47). The HR for dementia associated with the third quartile versus the lowest quartile was 1.48 (95% CI: 1.03, 2.11). A subanalysis that excluded a younger sample that had been retested after only 5 years of follow-up suggested stronger associations with exposure than were present in the full cohort (HR = 1.71; 95% CI: 1.08, 2.73 for the highest vs. the lowest quartile). Conclusions If the associations we observed are causal, then air pollution from traffic might be an important risk factor for vascular dementia and Alzheimer’s disease. Citation Oudin A, Forsberg B, Nordin Adolfsson A, Lind N, Modig L, Nordin M, Nordin S, Adolfsson R, Nilsson LG. 2016. Traffic

Metrafenone resistance in a population of Erysiphe necator in northern Italy.

PubMed

Kunova, Andrea; Pizzatti, Cristina; Bonaldi, Maria; Cortesi, Paolo

2016-02-01

Metrafenone has been used in Europe in integrated pest management programmes since 2006 to control powdery mildews, including Erysiphe necator. Its exact mode of action is not known, but it is unique among fungicide classes used in powdery mildew management. Recently, resistance to metrafenone was reported in Blumeria graminis f. sp. tritici. In this study we investigated metrafenone resistance in Erysiphe necator in northern Italy. Metrafenone efficacy to control grapevine powdery mildew was monitored in three consecutive years in the field, and its reduced activity was observed in 2013. Out of 13 monoconidial isolates, two sensitive strains were identified, which did not grow at the fungicide concentration recommended for field application. The remaining strains showed variable response to metrafenone, and five of them grew and sporulated similarly to the control, even at 1250 mg L(-1) of metrafenone. Moreover, the resistant strains showed cross-resistance to pyriofenone, which belongs to the same FRAC group as metrafenone. The results indicate the emergence of metrafenone resistance in an Italian population of Erysiphe necator. Further studies are needed to gain insight into the metrafenone's mode of action and to understand the impact of resistance on changes in the pathogen population structure, fitness and spread of resistant strains, which will be indicative for designing appropriate antiresistance measures. © 2015 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Epidemiological survey of amyotrophic lateral sclerosis in the province of Reggio Emilia, Italy: influence of environmental exposure to lead.

PubMed

Guidetti, D; Bondavalli, M; Sabadini, R; Marcello, N; Vinceti, M; Cavalletti, S; Marbini, A; Gemignani, F; Colombo, A; Ferrari, A; Vivoli, G; Solimè, F

1996-01-01

We carried out a retrospective incidence, prevalence and mortality survey of amyotrophic lateral sclerosis (ALS) in the province of Reggio Emilia, northern Italy. Based on 79 patients, the mean incidence per year for the period 1980 through 1992 was 1.5 cases per 100,000. On December 31st, 1992, the prevalence rate was 5.4 per 100,000. In the 10-year period of 1983-1992 the average mortality rate was 1.3 per 100,000 per year. The average age at onset was 61.3 +/- 10.2, the average survival period thereafter was 26.3 months +/- 17.7; 27.3 +/- 17.6 for classic ALS, 19.5 +/- 8.4 for progressive bulbar palsy and 36.3 +/- 41.4 for pseudopolyneuritic ALS. The incidence rate, recorded in public health district No.12, an area with documented lead pollution since the 1970s, was standardized to the sex and age of the population of the province. Its incidence and prevalence rate were comparable to the rates found in the remaining area of the province.

First record of the Asian bush mosquito, Aedes japonicus japonicus, in Italy: invasion from an established Austrian population.

PubMed

Seidel, Bernhard; Montarsi, Fabrizio; Huemer, Hartwig P; Indra, Alexander; Capelli, Gioia; Allerberger, Franz; Nowotny, Norbert

2016-05-16

In 2011 we identified the Asian bush mosquito, Aedes japonicus japonicus (Theobald, 1901) (Diptera: Culicidae) for the first time in northern Slovenia and in the bordering Austrian federal state of Styria. Between May and July 2012 the distribution area of Ae. j. japonicus was already found to be extended westwards into Carinthia and eastwards towards Burgenland and bordering Hungary. In August 2012 the species was first detected in a western province of Hungary. In subsequent years, follow-up field studies demonstrated an active spread westwards throughout Carinthia, reaching the border to northern Italy. In July 2015 several aquatic-stage specimens of the species were discovered at three different sites in the Friuli Venezia Giulia region, north-eastern Italy. In September 2015, co-occurrence of Ae. j. japonicus and Aedes albopictus (Skuse, 1895) was observed in the same sample in that region. Ae. j. japonicus actively extended its geographic range from an established population in Carinthia (Austria) southwards to northern Italy by crossing Alpine ranges. Since Ae. albopictus and Aedes koreicus (Edwards, 1917) are already well established in northern Italy, it will be pivotal to monitor the consequences of a third invasive mosquito species trying to populate the same geographic region.

Ischemic stroke subtype incidence among whites, blacks, and Hispanics: the Northern Manhattan Study.

PubMed

White, Halina; Boden-Albala, Bernadette; Wang, Cuiling; Elkind, Mitchell S V; Rundek, Tanja; Wright, Clinton B; Sacco, Ralph L

2005-03-15

Stroke incidence is greater in blacks than in whites; data on Hispanics are limited. Comparing subtype-specific ischemic stroke incidence rates may help to explain race-ethnic differences in stroke risk. The aim of this population-based study was to determine ischemic stroke subtype incidence rates for whites, blacks, and Hispanics living in one community. A comprehensive stroke surveillance system incorporating multiple overlapping strategies was used to identify all cases of first ischemic stroke occurring between July 1, 1993, and June 30, 1997, in northern Manhattan. Ischemic stroke subtypes were determined according to a modified NINDS scheme, and age-adjusted, race-specific incidence rates calculated. The annual age-adjusted incidence of first ischemic stroke per 100,000 was 88 (95% CI, 75 to 101) in whites, 149 (95% CI, 132 to 165) in Hispanics, and 191 (95% CI, 160 to 221) in blacks. Among blacks compared with whites, the relative rate of intracranial atherosclerotic stroke was 5.85 (95% CI, 1.82 to 18.73); extracranial atherosclerotic stroke, 3.18 (95% CI, 1.42 to 7.13); lacunar stroke, 3.09 (95% CI, 1.86 to 5.11); and cardioembolic stroke, 1.58 (95% CI, 0.99 to 2.52). Among Hispanics compared with whites, the relative rate of intracranial atherosclerotic stroke was 5.00 (95% CI, 1.69 to 14.76); extracranial atherosclerotic stroke, 1.71 (95% CI, 0.80 to 3.63); lacunar stroke, 2.32 (95% CI, 1.48 to 3.63); and cardioembolic stroke, 1.42 (95% CI, 0.97 to 2.09). The high ischemic stroke incidence among blacks and Hispanics compared with whites is due to higher rates of all ischemic stroke subtypes.

Space-time distribution of the ALS incident cases by onset type in the Health District of Ferrara, Italy.

PubMed

Govoni, V; Della Coletta, E; Cesnik, E; Casetta, I; Tugnoli, V; Granieri, E

2015-04-01

An ecological study in the resident population of the Health District (HD) of Ferrara, Italy, has been carried out to establish the distribution in space and time of the amyotrophic lateral sclerosis (ALS) incident cases according to the disease onset type and gender in the period 1964-2009. The hypothesis of a uniform distribution was assumed. The incident cases of spinal onset ALS and bulbar onset ALS were evenly distributed in space and time in both men and women. The spinal onset ALS incident cases distribution according to gender was significantly different from the expected in the extra-urban population (20 observed cases in men 95% Poisson confidence interval 12.22-30.89, expected cases in men 12.19; six observed cases in women 95% Poisson confidence interval 2.20-13.06, expected cases in women 13.81), whereas no difference was found in the urban population. The spinal onset ALS incidence was higher in men than in women in the extra-urban population (difference between the rates = 1.53, 95% CI associated with the difference 0.52-2.54), whereas no difference between sexes was found in the urban population. The uneven distribution according to gender of the spinal onset ALS incident cases only in the extra-urban population suggests the involvement of a gender related environmental risk factor associated with the extra-urban environment. Despite some limits of the spatial analysis in the study of rare diseases, the results appear consistent with the literature data. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Underwater noise assessment in the Gulf of Trieste (Northern Adriatic Sea, Italy) using an MSFD approach.

PubMed

Codarin, Antonio; Picciulin, Marta

2015-12-30

In the marine environment, underwater noise is one of the most widespread input of man-made energy. Recently, the European Commission has stressed the necessity of establishing threshold levels as a target for the descriptor 11.2.1 "Continuous low frequency sounds" in the Marine Strategy Framework Directive (MSFD). In 2012, a monthly underwater noise monitoring programme was conducted in the Gulf of Trieste (Northern Adriatic Sea, Italy); the collected acoustic samples (frequency range: 10-20,000 Hz) were analysed in the 1/3 octave bands. The stations have been further clustered following the 63 and 125 Hz bands noise levels. Average SPL levels resulted similar to those previously computed for proximate areas, indicating that the Adriatic Sea sub-region experiences high noise pressure in the marine waters. In its turn this claims for a scientific and technical international cooperation, as requested by the EU programme. No seasonal variation in local noise levels has been found. Copyright © 2015 Elsevier Ltd. All rights reserved.

Molecular characterization of hepatitis A outbreak in the province of Rome, Lazio region, Italy, January-July 2013.

PubMed

Capobianchi, Maria R; Garbuglia, Anna Rosa; Agrati, Chiara; Rianda, Alessia; Noto, Pasquale; Corpolongo, Angela; Cataldo, Maria Adriana; Rosati, Silvia; Zaccaro, Paola; Loffredo, Mariarosaria; Pompa, Maria Grazia; Girardi, Enrico; Scognamiglio, Paola; Ippolito, Giuseppe

2014-04-01

Reduced circulation of hepatitis A virus lead to an increase of susceptible individuals, and outbreaks occurred recently. In Northern Italy an outbreak is ongoing, attributed to a monophyletic genotype IA strain, with mixed frozen berries as probable source. From 01/01/2013 to 07/15/2013, 30 cases were diagnosed at National Institute for Infectious Diseases, Rome, Italy, representing about twice the number of cases in whole 2012. Phylogenetic analysis indicated that most, although not all, infections were attributable to the same monophyletic genotype IA strain identified in the contemporary Northern Italy outbreak. This strain is also very similar to previous isolates from Venezuela. Copyright © 2014 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

End-of-life care across Southern Europe: a critical review of cultural similarities and differences between Italy, Spain and Portugal.

PubMed

Meñaca, Arantza; Evans, Natalie; Andrew, Erin V W; Toscani, Franco; Finetti, Silvia; Gómez-Batiste, Xavier; Higginson, Irene J; Harding, Richard; Pool, Robert; Gysels, Marjolein

2012-06-01

Evidence from a range of sources demonstrates that end-of-life (EoL) care practices and preferences vary across countries; culture is consistently one of the main explanations given for this. In order to understand how cultural factors are used to explain similarities and differences in EoL care between Spain, Italy and Portugal, database and hand searches were performed and cross-cutting core themes identified. Similarities included higher proportions of people who wished to die at home than actually died at home, a persistent trend for partial disclosure in Italy and Spain, low use of advance directives, and low incidence of all medical EoL decisions (with the exception of terminal sedation) compared to northern European countries. The role of religion and the importance of family ties were the two main cultural factors used to explain the similarities. Further research is needed in order to interpret the important differences that were also found. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

The distribution and incidence of white pine blister rust in central and southeastern Wyoming and northern Colorado

Treesearch

Holly S. J. Kearns; William R. Jacobi

2007-01-01

A survey of limber pine (Pinus flexilis James) to determine the geographic distribution, incidence, and severity of white pine blister rust (WPBR) throughout 13 study areas in central and southeastern Wyoming and northern Colorado was conducted from 2002 to 2004. The majority (81.1%) of the 18719 surveyed limber pines>1.37 m tall were classified...

Biological Correlates of Northern-Southern Italy Differences in IQ

ERIC Educational Resources Information Center

Templer, Donald I.

2012-01-01

The present study was intended to provide perspective, albeit less than unequivocal, on the research of Lynn (2010) who reported higher IQs in the northern than southern Italian regions. He attributes this to northern Italians having a greater genetic similarity to middle Europeans and southern Italians to Mediterranean people. Higher regional IQ…

Intake of arsenic and mercury from fish and seafood in a Northern Italy community.

PubMed

Filippini, Tommaso; Malavolti, Marcella; Cilloni, Silvia; Wise, Lauren A; Violi, Federica; Malagoli, Carlotta; Vescovi, Luciano; Vinceti, Marco

2018-06-01

Regular consumption of fish is generally recommended by authorities because fish is an important source of essential nutrients. However, the presence of potentially toxic contaminants in fish has raised many concerns about the food's safety for human health. In the present study, we used a validated semi-quantitative food frequency questionnaire to assess the dietary habits of a representative sample of 719 individuals (319 males and 400 females) aged 18-87 years residing in Northern Italy. We estimated weekly dietary intakes of Arsenic (As) and Mercury (Hg), and we compared them with safety standards set by the European Food Safety Authority. In this population, fish was the main contributor to As and Hg intake. The highest levels of As were in sardine, sole/flounder and cephalopods, and of Hg in the biggest, predatory fish. About the other foods, cereals were the second contributor to the intake of these elements, especially rice for As and bread for Hg, and high levels of As and Hg were also found in mushrooms, coffee and wine. Average weekly intake of both contaminants was below recommended safety limits. Copyright © 2018 Elsevier Ltd. All rights reserved.

Seismic shaking scenarios in realistic 3D crustal model of Northern Italy

NASA Astrophysics Data System (ADS)

Molinari, I.; Morelli, A.; Basini, P.; Berbellini, A.

2013-12-01

Simulation of seismic wave propagation in realistic crustal structures is a fundamental tool to evaluate earthquake-generated ground shaking and assess seismic hazard. Current-generation numerical codes, and modern HPC infrastructures, allow for realistic simulations in complex 3D geologic structures. We apply such methodology to the Po Plain in Northern Italy -- a region with relatively rare earthquakes but having large property and industrial exposure, as it became clear during the two M~6 events of May 20-29, 2012. Historical seismicity is well known in this region, with maximum magnitudes estimates reaching M~7, and wave field amplitudes may be significantly amplified by the presence of the very thick sedimentary basin. Our goal is to produce estimates of expected ground shaking in Northern Italy through detailed deterministic simulations of ground motion due to expected earthquakes. We defined a three-dimensional model of the earth's crust using geo-statistical tools to merge the abundant information existing in the form of borehole data and seismic reflection profiles that had been shot in the '70s and the '80s for hydrocarbon exploration. Such information, that has been used by geologists to infer the deep structural setup, had never been merged to build a 3D model to be used for seismological simulations. We implement the model in SPECFEM3D_Cartesian and a hexahedral mesh with elements of ~2km, that allows us to simulate waves with minimum period of ~2 seconds. The model has then been optimized through comparison between simulated and recorded seismograms for the ~20 moderate-magnitude events (Mw > 4.5) that have been instrumentally recorded in the last 15 years. Realistic simulations in the frequency band of most common engineering relevance -- say, ~1 Hz -- at such a large scale would require an extremely detailed structural model, currently not available, and prohibitive computational resources. However, an interest is growing in longer period ground

Cancer incidence following long-term consumption of drinking water with high inorganic selenium content.

PubMed

Vinceti, Marco; Vicentini, Massimo; Wise, Lauren A; Sacchettini, Claudio; Malagoli, Carlotta; Ballotari, Paola; Filippini, Tommaso; Malavolti, Marcella; Rossi, Paolo Giorgi

2018-04-16

Selenium, a trace element to which humans are exposed mainly through diet, has been involved in the etiology of human cancer. We investigated the long-term effects of selenium exposure on cancer incidence using data from a natural experiment in Northern Italy. During the 1970s-1980s, in a part of the Italian municipality of Reggio Emilia, residents were inadvertently exposed to unusually high levels of inorganic hexavalent selenium (selenate) through drinking water. We followed the exposed residents for 28years, generating data on incidence (when available) and mortality rates for selected cancer sites; the remaining municipal residents comprised the unexposed (reference) group. We observed no substantial difference in overall cancer incidence comparing exposed and unexposed cohorts. We detected, however, a higher incidence of cancer at some sites, and for a few of them, namely cancers of the buccal cavity and pharynx, melanoma, urinary tract and lymphoid tissue, the excess incidence was particularly evident in the first period of follow-up but decreased over time. Overall, these results suggest that consumption of water with levels of selenium in its inorganic hexavalent form close to the European standard, 10μg/L, may have unfavourable effects on cancer incidence. Copyright © 2018 Elsevier B.V. All rights reserved.

Myth and Reality: A Response to Lynn on the Determinants of Italy's North-South Imbalances

ERIC Educational Resources Information Center

Felice, Emanuele; Giugliano, Ferdinando

2011-01-01

In his article "In Italy, North-South differences in IQ predict differences in income, education, infant mortality, stature, and literacy," Richard Lynn claims to have found the reason causing the divergence between the Northern and the Southern regions of Italy. This article identifies the four main hypotheses formulated in his paper…

Biomarker Tools to Design Clinical Vaccines Determined from a Study of Annual Listeriosis Incidence in Northern Spain

PubMed Central

Calderon-Gonzalez, Ricardo; Teran-Navarro, Hector; Marimon, José María; González-Rico, Claudia; Calvo-Montes, Jorge; Frande-Cabanes, Elisabet; Alkorta-Gurrutxaga, Miriam; Fariñas, M. C.; Martínez-Martínez, Luis; Perez-Trallero, Emilio; Alvarez-Dominguez, Carmen

2016-01-01

Two regions of northern Spain, Gipuzkoa, and Cantabria present high annual incidence of listeriosis (1.86 and 1.71 cases per 100,000 inhabitants, respectively). We report that the high annual incidences are a consequence of infection with highly virulent Listeria monocytogenes isolates linked to fatal outcomes in elderly patients with cancer. In addition, listeriosis patients with cancer present low IL-17A/IL-6 ratios and significantly reduced levels of anti-GAPDH1–22 antibodies, identified as two novel biomarkers of poor prognosis. Analysis of these biomarkers may aid in reducing the incidence of listeriosis. Moreover, GAPDH1–22-activated monocyte-derived dendritic cells of listeriosis patients with cancer seem useful tools to prepare clinical vaccines as they produce mainly Th1 cytokines. PMID:27965668

Landfill restoration and biodiversity: a case of study in Northern Italy.

PubMed

Camerini, Giuseppe; Groppali, Riccardo

2014-08-01

Landfilling is a worldwide common waste treatment method. Final recovery usually consists of capping the area with top soil on which vegetation can grow. Depending on the suitability of the recovery pattern, landfill sites can work as potential reserve of semi-natural habitats. A recovery pattern applied to land reclamation of two hazardous waste landfills sited in Northern Italy (Po floodplain) was studied to assess the results in terms of biodiversity. These landfills lie within a landscape dominated by intensive agriculture. After final sealing, both landfills were covered by soil on which a meadow was sown and a hedgerow was planted around the borders. One of the compared areas was not provided with a pond and the hedgerow was incomplete. Butterflies and birds were used as indicators, and their seasonal abundance was related to habitat structure and ecological factors. Meadows grown on both areas supported a rich butterfly population (30 species), including some species that are by now uncommon in the Po floodplain. In both areas butterfly abundance was affected by summer drought. The birds' community included 57 species; 16 Species of European Conservation Concern (SPECs) were observed. Each bird community was different in the compared study areas because of their different size and habitat structure. For example, landfill A, provided with a pond and a more complex structure of the hedgerow, supported a richer birds community (52 species versus 39). Both restored landfills worked well as a stepping stone for migratory birds, but they were a reproductive habitat of poor quality. © The Author(s) 2014.

Temporal trend of amyotrophic lateral sclerosis incidence in southern Europe: a population study in the health district of Ferrara, Italy.

PubMed

Govoni, Vittorio; Cesnik, Edward; Casetta, Ilaria; Tugnoli, Valeria; Tola, Maria Rosaria; Granieri, Enrico

2012-08-01

Data about the temporal trend of amyotrophic lateral sclerosis (ALS) incidence in southern Europe are scarce. Incidence studies on ALS have been carried out in the health district of Ferrara, Italy, since 1960s. We expanded the previous studies from 1964 to 2009. The study was prospective with a subsequent retrospective intensive survey of multiple sources of case ascertainment. All patients with a definite and probable ALS according to the original El Escorial criteria were selected. There were 130 incident cases in the years 1964-2009 giving an average annual crude incidence of 1.82 per 100,000 population (95% CI 1.53-2.17). An incidence increase during the study period was estimated in women (χ(2) test for trend = 7.19, p < 0.01) and in the elderly (χ(2) test for trend = 7.803, p < 0.01). The age-adjusted incidence was stable over time in both women (1.19 per 100,000, 95% CI 0.90-1.52) and men (1.45 per 100,000, 95% CI 0.12-1.84). The annual number of new ALS cases in the study population followed the Poisson distribution in both sexes as well as in the elderly group of the population. The present findings suggest that ALS incidence is nearly stable over time. The crude incidence increase we estimated over time among women is mainly explained by population ageing. The increasing incidence in the elderly population was likely the consequence of an increasing precision in ALS diagnosis in the elderly since the increasing attention and care over time of neurologic elderly patients that likely concern elderly women more than previous time periods rather than better case ascertainment of diagnosed patients. The present findings do not support the role of specific environmental factors in ALS pathogenesis.

[The incidence of dental caries during childhood. A clinical and epidemiologic study in Matera (Southern Italy)].

PubMed

Bottalico, L; Valenzano, A; Leone, D; Mangini, F; Santacroce, L

2007-01-01

The aim of the present study is to obtain comprehensive epidemiological data of the incidence of oral and dental health conditions in an Italian homogeneous population of schoolchildren. The study has been performed on schoolchildren born, living and attending the primary school in Matera, Basilicata, Southern Italy. Such data have been compared with the alimentary habits of the participants to the study, as well as with the social-economic family situations and with the social-environmental data. The data show a marked difference in the habits of oral hygiene, and in the health status of the oral structures also, based on both the sex and the environment of life. Such differences in the prevalence of caries among various urban areas and the behavioural habits related to sex and age ratios may be very useful findings for future regional prevention programs.

Relationship between socio-economic and cultural status, psychological factors and body fat distribution in middle-aged women living in Northern Italy.

PubMed

Cota, D; Vicennati, V; Ceroni, L; Morselli-Labate, A M; Pasquali, R

2001-12-01

This study analyses the relationships between body fat distribution and socioeconomic and psychological factors in a cohort of 426 healthy middle-aged women living in Virgilio, Mantua (Northern Italy). The information concerning their occupational, social and psychological conditions and smoking habits were obtained by means of questionnaires. Psychological factors were investigated using the Italian version of the Illness Behaviour Questionnaire and the Symptom Questionnaire. Anthropometric measurements, body mass index (BMI) (kg/m2), waist/hip ratio (WHR) and clinical/hormonal menopausal status were also collected for each subject. The women reported significantly higher or lower psychological factor scores (symptoms of conversion: p=0.005; perception of disease: p=-0.018; denial: p=0.021; hostility: p=0.57; and laxity: p=0.047) as their WHR increased, thus indicating some concern about their health. In a multiple regression model, their WHR and waist circumference (W) significantly correlated with symptoms of conversion (p=0.005 and p=0.029), and W was also significantly related to the perception of disease (p=0.043). There was a significant inverse correlation between the WHR and educational level (p<0.001). The prevalence of partners who were entrepreneurs or self-employed also decreased as WHR increased (p<0.001). Furthermore, the number of women living in the centre of town significantly diminished, whereas those living in the suburbs or in the country significantly increased (p=0.005). However, using age, BMI and menopausal status as covariates, only the partner's work significantly and negatively correlated with the WHR (p=0.029). These results are consistent with the hypothesis that psychological and socio-economic handicaps are associated with a higher prevalence of abdominal fatness in middle-aged women living in Northern Italy

Incidence of status epilepticus in southern Europe: a population study in the health district of Ferrara, Italy.

PubMed

Govoni, Vittorio; Fallica, Elisa; Monetti, Vincenza Cinzia; Guerzoni, Franco; Faggioli, Raffaella; Casetta, Ilaria; Granieri, Enrico

2008-01-01

The epidemiologic features of status epilepticus (SE) are still in the course of definition. We carried out an intensive survey of multiple sources of case material in the resident population of the health district of Ferrara, Italy, in 2003. Information was collected on age, gender, duration, seizure type and etiology of SE. The age- adjusted annual incidence rate of SE was 27.2/100,000 (95% CI = 19.4-36.9) and it was higher in men (41.7/100,000, 95% CI = 26.9-61.7) than in women (12.3/100,000, 95% CI = 6.9-20.4). The incidence was higher in the elderly (older than 60 years, 39.2/100,000) than in younger adults in the age group 20-59 years (14.7/100,000). The age-specific incidence showed a bimodal distribution peaking in the youngest (0-4 years) and in the oldest age group (75+ years). Cerebrovascular disease was the most frequent etiologic factor (45%). Epilepsy had previously been diagnosed in 40% of the patients. The case fatality was 5%. The study found a higher incidence of SE than that expected on the basis of the previous European studies suggesting that the risk of SE in southern Europe is higher and more similar to that estimated in population studies in the United States. The case fatality was lower than that reported in previous South-European population studies despite the similar clinical features of the patients. Indirect evidence suggests that several factors related to the SE management could have positively influenced the outcome. Copyright 2007 S. Karger AG, Basel.

Landfill aeration in the framework of a reclamation project in Northern Italy.

PubMed

Raga, Roberto; Cossu, Raffaello

2014-03-01

In situ aeration by means of the Airflow technology was proposed for landfill conditioning before landfill mining in the framework of a reclamation project in Northern Italy. A 1-year aeration project was carried out on part of the landfill with the objective of evaluating the effectiveness of the Airflow technology for landfill aerobization, the evolution of waste biological stability during aeration and the effects on leachate and biogas quality and emissions. The main outcomes of the 1-year aeration project are presented in the paper. The beneficial effect of the aeration on waste biological stability was clear (63% reduction of the respiration index); however, the effectiveness of aeration on the lower part of the landfill is questionable, due to the limited potential for air migration into the leachate saturated layers. During the 1-year in situ aeration project approx. 275 MgC were discharged from the landfill body with the extracted gas, corresponding to 4.6 gC/kgDM. However, due to the presence of anaerobic niches in the aerated landfill, approx. 46% of this amount was extracted as CH4, which is higher than reported in other aeration projects. The O2 conversion quota was lower than reported in other similar projects, mainly due to the higher air flow rates applied. The results obtained enabled valuable recommendations to be made for the subsequent application of the Airflow technology to the whole landfill. Copyright © 2013 Elsevier Ltd. All rights reserved.

Incidence and risk factors for intussusception among children in northern Israel from 1992 to 2009: a retrospective study.

PubMed

Muhsen, Khitam; Kassem, Eias; Efraim, Sigalit; Goren, Sophy; Cohen, Dani; Ephros, Moshe

2014-08-31

Determining the background incidence of intussusception is important in countries implementing rotavirus immunization. Rotavirus immunization was introduced into the routine infant immunization program in Israel during late 2010. Incidence and risk factors for intussusception were examined in children aged less than five years between 1992 and 2009. Data were collected from medical records of children hospitalized due to intussusception (N = 190), and from control children (N = 295), at Carmel and Hillel Yaffe hospitals in northern Israel. The average annual incidence of intussusception in Jewish and Arab children aged less than five years was estimated at 36.1 (95% CI 17.0-76.5) vs. 23.2 per 100,000 (95% CI 9.3-57.9); for infants less than 12 months of age- 128.1 (95% CI 53.0-309.6) vs. 80.1 (95% CI 29.1-242.6) per 100,000. The risk of intussusception was higher in infants aged 3-5 months: OR 5.30 (95% CI 2.11-13.31) and 6-11 months: OR 2.53 (95% CI 1.13-5.62) when compared to infants aged less than 3 months; in those living in low vs high socioeconomic communities: OR 2.81 (95% CI 1.45-5.43), and in children with recent gastroenteritis: OR 19.90 (95% CI 2.35-168.32) vs children without recent gastroenteritis. Surgical reduction was required in 23.2%. The likelihood of surgery was significantly increased in patients presenting with bloody stool, in Arabs and those who were admitted to Hillel Yaffe Hospital. The incidence of intussusception prior to universal rotavirus immunization was documented in northern Israel. Despite the lower incidence, Arab patients underwent surgery more often, suggesting delayed hospital admission of Arab as opposed to Jewish patients.

Robotic surgery in Italy national survey (2011).

PubMed

Santoro, Eugenio; Pansadoro, Vito

2013-03-01

Robotic surgery in Italy has become a clinical reality that is gaining increasing acceptance. As of 2011 after the United States, Italy together with Germany is the country with the largest number of active Robotic centers, 46, and da Vinci Robots installed, with at least 116 operators already trained. The number of interventions performed in Italy in 2011 exceeded 6,000 and in 2010 were 4,784, with prevalence for urology, general surgery and gynecology, however these interventions have also begun to be applied in other fields such as cervicofacial, cardiothoracic and pediatric surgery. In Italy Robotic centers are mostly located in Northern Italy, while in the South there are only a few centers, and four regions are lacking altogether. Of the 46 centers which were started in 1999, the vast majority is still operational and almost half handle over 200 cases a year. The quality of the work is also especially high with large diffusion of radical prostatectomy in urology and liver resection and colic in general surgery. The method is very well accepted among operators, over 80 %, and among patients, over 95 %. From the analysis of world literature and a survey carried out in Italy, Robotic surgery, which at the moment could be better defined as telesurgery, represents a significant advantage for operators and a consistent gain for the patient. However, it still has important limits such as high cost and non-structured training of operators.

Attenuation in the Upper Mantle Beneath the Northern Apennines (Italy) from Teleseismic P- and S-Wave Spectra

NASA Astrophysics Data System (ADS)

Lucente, F. P.; Piccinini, D.; Dibona, M.; Levin, V.; Park, J.

2007-12-01

We present preliminary results for seismic attenuation in the mantle beneath the Italian region. We estimate P- and S-wave spectral ratios from teleseisms recorded at the temporary broadband seismic network deployed during the RETREAT (Retreating-TRrench, Extension, and Accretion Tectonics) project. We examine body-wave attenuation variation across the northern part of the Apennines mountain belt, which represents the accretionary wedge exposed during recent episodes of the subduction process in Italy. The data recorded during the three-year seismic campaign were analyzed using an ad hoc semi-automated procedure based on the cross-correlation analysis of a single phase across all the stations for each event. The seismic phases analyzed (P, S, SKS) display different patterns of seismic attenuation. Furthermore, we observe systematic variations in the distribution of the attenuation values as function of both the azimuth and the incidence angle of the seismic rays. Relatively high attenuation values are found on the Tyrrhenian side by seismic rays coming from the SW for both P- and S-phases. For NE-approaching rays the pattern of high attenuation values varies considerably, depending on the seismic phases: for P-waves it grossly corresponds to the mountain belt, while for S-waves it extends over almost the whole study area. By correlating attenuation estimates and the velocity structure from the existing tomographic models, we can make some inferences on the thermal state of the sublithospheric mantle, and on the physical properties of the tectonic elements which constitute the subduction system in the region. From the analysis of the P-phases we can clearly distinguish three main areas with different attenuation values, corresponding to the back-arc mantle (high attenuation), to the slab (low attenuation) and to the retro-slab mantle (high attenuation). The correspondence between the identified elements of the subduction system and the S- waves attenuation is not

Genetic analysis of human and swine influenza A viruses isolated in Northern Italy during 2010-2015.

PubMed

Chiapponi, C; Ebranati, E; Pariani, E; Faccini, S; Luppi, A; Baioni, L; Manfredi, R; Carta, V; Merenda, M; Affanni, P; Colucci, M E; Veronesi, L; Zehender, G; Foni, E

2018-02-01

Influenza A virus (IAV) infection in swine plays an important role in the ecology of influenza viruses. The emergence of new IAVs comes through different mechanisms, with the genetic reassortment of genes between influenza viruses, also originating from different species, being common. We performed a genetic analysis on 179 IAV isolates from humans (n. 75) and pigs (n. 104) collected in Northern Italy between 2010 and 2015, to monitor the genetic exchange between human and swine IAVs. No cases of human infection with swine strains were noticed, but direct infections of swine with H1N1pdm09 strains were detected. Moreover, we pointed out a continuous circulation of H1N1pdm09 strains in swine populations evidenced by the introduction of internal genes of this subtype. These events contribute to generating new viral variants-possibly endowed with pandemic potential-and emphasize the importance of continuous surveillance at both animal and human level. © 2017 The Authors. Zoonoses and Public Health published by Blackwell Verlag GmbH.

Who Are the Subjects with Gambling-Related Problems Requiring Treatment? A Study in Northern Italy.

PubMed

Pavarin, Raimondo Maria; Fioritti, Angelo; Marani, Silvia; Gambini, Daniele; Turino, Elsa; Piazza, Antonella

2018-04-13

This study analyzes data related to Hospital (HOS), Public Treatment Service Dedicated to Drug Addicts (SERD), or Community Mental Health Center (CMHC) clients with a first diagnosis of Pathological Gambling (PG) in the period 2000/2016 in Northern Italy. The aims were to describe trends and characteristics of pathological gamblers (PGs) and to estimate the prevalence of other diagnoses before or after the diagnosis of PG. Participants aged over 17 years with an ICD-9 or ICD-10 PG diagnosis were selected. 680 PGs were identified, mean age 47.4 years, 20% female, 13% non-natives, 30% had other mental disorders diagnoses, 9% had alcohol dependence syndrome, and 11% had drug dependence. Most participants with comorbid disorders were diagnosed before PG, with a more elevated prevalence regarding mental disorders. Almost seven years had elapsed on average between the first admission and the diagnosis of PG. The results of this study highlight a growing demand for PG treatment addressed not only to SERD, but also to psychiatric and hospital services, based on the increase in SERD attendance from 2013. Many of them had already been treated for mental health problems before, but their percentage remained costant over time.

Survey on the prevention and incidence of haemolytic disease of the newborn in Italy

PubMed Central

Bennardello, Francesco; Curciarello, Giuseppe

2013-01-01

Background In 2010, the Italian Society of Immunohaematology and Transfusion Medicine (SIMTI) carried out a survey of the incidence of haemolytic disease of the newborn (HDN) and the prevention of HDN caused by anti-Rh(D) in Italian Transfusion Structures (TS). Materials and methods A questionnaire divided into the following five sections was administered: (i) types of services provided and maintenance of legally required registers, (ii) immunoprophylaxis (IP), (iii) red cell typing and searches for irregular antibodies, (iv) evaluation of foetal-maternal haemorrhage (FMH), and (v) incidence of HDN in 2010. Of the 280 TS sent the questionnaire, 176 (63%) replied. Results A HDN register was available in 55.5% of the TS (n =91). Immunoprophylaxis with a dose of anti-D IgG was given to all Rh(D) negative and Rh(D) variant puerpera with Rh(D) positive newborns: in more than 93% of cases the dose was between 1,500 IU (300 μg) and 1,250 IU (250 μg). Antenatal IP between the 25th and 28th week was proposed by 42 TS (26%). Seventy percent of the TS (n =115) did not make any evaluation of FMH. The number of births surveyed in 2010 was 203,384, the number of Rh(D) negative pregnancies was 13,569, while anti-D antibodies were present in 245 pregnancies. There were 111 cases of HDN due to anti Rh(D) incompatibility and in 40 of these, intrauterine transfusion (n =8) or exchange transfusion (n =32) was necessary. In 94 cases HDN was due to other irregular antibodies: in 4 of these cases intrauterine transfusion was needed and in 11 other recourse was made of exchange transfusion. Finally, there were 1,456 newborns with ABO HDN of whom 13 underwent exchange transfusion. Discussion The data collected give a picture of the incidence of HDN in Italy and of the methods of managing IP and could form the basis for an update of the SIMTI recommendations on the management and prevention of this disease. PMID:23867179

Cancer incidence and mortality in the province of Ferrara 1989-1990.

PubMed

Ferretti, S; Tassinari, D; Albonico, G; Nenci, I

1995-01-01

Mortality data have clearly highlighted the province of Ferrara as an area with a particular distribution of tumors strictly related with environmental factors. The project of a tumor registry has been planned for a better description of cancer incidence and for a deeper insight into etiologic factors, considering the typical features of the province from geographic and occupational points of view. This study presents the registration results of the first 2 years, in order to verify the quality level of data recruitment and to confirm that observed in previous studies. The population covered by the registry was 151,968 males and 165,835 females, with high representation of the elderly. In this period 2,087 tumors in men and 1,778 in women were observed. Lung cancer reaches one of the highest levels in Italy, according to that observed in Lombardy and Veneto regions and the northern Adriatic coast. Incidence and mortality are, however, significantly higher than in other Emilia-Romagna areas, as pointed out by the registries of Parma, Modena and Forii. Colon cancer also presents high frequencies in comparison with neighboring areas, whereas non-Hodgkin lymphomas reach the highest level in Italy. Gastric tumors, although well represented in males and females, show lower levels than the high-risk neighboring Romagna region. In women, a low incidence of cervix uteri-tumors and high levels of breast cancer have also been observed. The distribution of such neoplasms and the differences observed among neighboring areas deserve further analytical studies, with the aim of a better reading of cancer onset and diffusion. The quality of data obtained (about 70% of histocytologic confirmations, and 5% of "final" death-certificate-only cases), appears to reach satisfying levels, considering the starting phase of the registry.

Investigation and monitoring in support of the structural mitigation of large slow moving landslides: an example from Ca' Lita (Northern Apennines, Reggio Emilia, Italy)

NASA Astrophysics Data System (ADS)

Corsini, A.; Borgatti, L.; Caputo, G.; de Simone, N.; Sartini, G.; Truffelli, G.

2006-01-01

The Ca' Lita landslide is a large and deep-seated mass movement located in the Secchia River Valley, in the sector of the Northern Apennines falling into Reggio Emilia Province, about 70 km west of Bologna (Northern Italy). It consists of a composite landslide system that affects Cretaceous to Eocene flysch rock masses and chaotic complexes. Many of the components making up the landslide system have resumed activity between 2002 and 2004, and are now threatening some hamlets and an important road serving the upper watershed area of River Secchia, where many villages and key industrial facilities are located. This paper presents the analysis and the quantification of displacement rates and depths of the mass movements, based on geological and geomorphological surveys, differential DEM analysis, interpretation of underground stratigraphic and monitoring data collected during the investigation campaign that has been undertaken in order to design cost-effective mitigation structures, and that has been conducted with the joint collaboration between public offices and research institutes.

Active stress along the ne external margin of the Apennines: the Ferrara arc, northern Italy

NASA Astrophysics Data System (ADS)

Montone, Paola; Mariucci, M. Teresa

1999-09-01

We have analysed borehole breakout data from 12 deep wells in order to constrain the direction of the minimum and maximum horizontal stress in a part of the Po Plain, northern Italy, characterised by a ˜N-S prevailing compressional stress regime, and in order to shed light on the regional state of stress and on the correlation between the active stress field and the orientation of tectonic structures. The results have been compared with seismological data relating to 1988-1995 crustal seismicity (2.5< Md<4.8) and to the 1983 Parma ( Ms=5.0) and the 1996 Reggio Emilia ( Ms=5.1) events. Plio-Pleistocene mesostructural data are also described in order to better define the present-day stress field and to understand the active tectonic processes in particular stress provinces. The borehole breakout analysis, in accordance with the seismicity and mesostructural data, shows the presence of a predominant compression area, characterised by approximately N-S maximum horizontal stress, along the outer thrust of the Ferrara arc. Particularly, the breakout analysis indicates a minimum horizontal stress, N81W±22° relative to a total of eleven analysed wells, with 3746 m cumulative total length of breakout zones. Among these, nine wells are located in the same tectonic structure, consisting of an arc of asymmetric folds overthrust towards the NE. The breakout results for these wells are quite similar in terms of minimum horizontal stress direction (˜E-W oriented). The other two wells are located in the outside sector of the arc and one of them shows a different minimum horizontal stress direction, probably distinctive of another tectonic unit. On the basis of these new reliable stress indicators, the active compressive front in this area is located along the termination of the external northern Apenninic arc.

Foreign children with cancer in Italy

PubMed Central

2011-01-01

Background There has been a noticeable annual increase in the number of children coming to Italy for medical treatment, just like it has happened in the rest of the European Union. In Italy, the assistance to children suffering from cancer is assured by the current network of 54 centres members of the Italian Association of Paediatric Haematology and Oncology (AIEOP), which has kept records of all demographic and clinical data in the database of Mod.1.01 Registry since 1989. Methods We used the information stored in the already mentioned database to assess the impact of immigration of foreign children with cancer on centres' activity, with the scope of drawing a map of the assistance to these cases. Results Out of 14,738 cases recorded by all centres in the period from 1999 to 2008, 92.2% were born and resident in Italy, 4.1% (608) were born abroad and living abroad and 3.7% (538) were born abroad and living in Italy. Foreign children cases have increased over the years from 2.5% in 1999 to. 8.1% in 2008. Most immigrant children came from Europe (65.7%), whereas patients who came from America, Asia and Oceania amounted to 13.2%, 10.1%, 0.2%, respectively. The immigrant survival rate was lower compared to that of children who were born in Italy. This is especially true for acute lymphoblastic leukaemia patients entered an AIEOP protocol, who showed a 10-years survival rate of 71.0% vs. 80.7% (p < 0.001) for immigrants and patients born in Italy, respectively. Conclusions Children and adolescents are an increasingly important part of the immigration phenomenon, which occurs in many parts of the world. In Italy the vast majority of children affected by malignancies are treated in AIEOP centres. Since immigrant children are predominantly treated in northern Italy, these centres have developed a special expertise in treating immigrant patients, which is certainly very useful for the entire AIEOP network. PMID:21923939

Identification of dangerous fibers: some examples in Northern Italy

NASA Astrophysics Data System (ADS)

Zanetti, Giovanna; Marini, Paola; Giorgis, Ilaria

2016-04-01

The presence of asbestiform minerals has to be foreseen in the planning of infrastructural activities: Asbestos can be a component of sedimentary rocks or of mafic and ultra mafic metamorphic rocks. Surveys and core drilling, in addition to providing important information on the quality of the rock and its geotechnical characteristics, allow for a prediction of the presence of asbestiform minerals in the areas affected by mining or infrastructural activities. During the excavation, workers can be exposed to the asbestos risk, therefore, the control of the air quality and of the excavated materials are fundamental for the safety of involved people. In this work some problems we met in the analysis of airborne filters and bulk samples from sites in northern Italy are presented. The asbestos fibers present in rocks as accessory minerals, are often different in habit and dimension from the well-known asbestos fibers used as industrial minerals and moreover can be erroneously identified as minerals morphologically and chemically similar present in the same rock or environment. In the case of tunnel muck it could be contaminated by substances used for the excavation that could modify colours and optical properties of asbestos minerals. In the PCOM (Phase Contrast Optical Microscope) analysis chrysotile, sepiolite and antigorite, due to their different refraction index, when the fibers have dimension > 0,5 micron and aren't contaminated by lubricant can be easely identified even if the morphology of chrysotile is very similar to that of sepiolite. In Electron Scanning Microscope (SEM) the discrimination between chrysotile and antigorite on the airborne filters is not always possible because the fibers of thin dimensions show similar habit and spectrum. In the case of the tremolite amphibole, morphology changes from prismatic to fibrous depending on its origin (p.eg. Monastero, Val Grana, Verrayes, Brachiello). Both prismatic and asbestiform tremolite (Gamble and Gibbs

Changes in patterns of uveitis at a tertiary referral center in Northern Italy: analysis of 990 consecutive cases.

PubMed

Luca, Cimino; Raffaella, Aldigeri; Sylvia, Marchi; Valentina, Mastrofilippo; Fabiana, Viscogliosi; Marco, Coassin; Annamaria, Soldani; Luisa, Savoldi; Alessandro, De Fanti; Lucia, Belloni; Alessandro, Zerbini; Maria, Parmeggiani; Matthew, Chersich; Alessandra, Soriano; Carlo, Salvarani; Luigi, Fontana

2018-02-01

The role of uveitis, an uncommon ocular disease, is often neglected in research and treatment of autoimmune conditions. The study described the spectrum of uveitis at a referral center in North Italy, and compared that to a previously published series of patients. We reviewed all patients with uveitis diagnosed from 2013 to 2015 at the Immunology Eye Unit, Arcispedale S. M. Nuova-IRCCS, Reggio Emilia, Italy. We examined patient characteristics, disease spectrum, and etiologies. In total, 990 cases of uveitis were identified, who were mostly female (59%) with a median age at presentation of 44 years (interquartile range = 29-57). Anterior uveitis was most frequent (53.5%), followed by panuveitis (22.8%), posterior (16.2%), and intermediate uveitis (5.5%). Anterior herpetic uveitis (15.6%), Fuchs uveitis (9.7%), and HLA-B27 positive anterior uveitis (7.7%) were the most common specific diagnoses. Compared with the previous series, we observed an increased incidence of uveitis, and a different pattern of diagnoses. Rates of herpetic, HLA-B27 positive uveitis, and presumed ocular tuberculosis were higher, but Fuchs uveitis was less frequent. The pattern of uveitis appears to be changing, very likely due to population-level increases in infectious diseases, to the availability of new diagnostic tests and to the interdisciplinary approach used in patient diagnosis.

Epidemiology of Idiopathic Pulmonary Fibrosis in Northern Italy

PubMed Central

Caminati, Antonella; Conti, Sara; Cesana, Giancarlo

2016-01-01

Background Idiopathic pulmonary fibrosis (IPF) is the most common and severe form of idiopathic interstitial pneumonia. Despite its clinical relevance, few studies have examined the epidemiology of IPF and temporal variation in disease incidence and prevalence. Aim of the study was to investigate the prevalence, incidence and trends of IPF in Lombardy, a region with nearly 10 million inhabitants, during 2005–2010. Methods For the identification of IPF patients, we used healthcare administrative databases of Lombardy Healthcare System and adopted three algorithms: generic, broad and narrow case definition (GCD, BCD, NCD). IPF cases were identified according to diagnoses reported in inpatient and outpatient claims occurred during 2000–2010. We estimated age- and sex-adjusted annual prevalence and incidence rates from 2005 to 2010, thus allowing for a 5-year washout period. Results The mean annual incidence rate was estimated at 2.3 and 5.3 per 100,000 person-years using NCD and GCD, respectively. IPF incidence was higher among males, and increased with age. Trend remained stable over the years. The estimated annual prevalence rate was 35.5, 22.4, and 12.6 per 100,000 person-years using GCD, BCD and NCD, respectively, and increased with age. Moreover, we observed a positive trend over the years. Using BCD and NCD, prevalence was higher among males. Conclusions The results of this study, which is one of the largest population-based survey ever conducted according to strict criteria, indicated that prevalence of IPF increased across the years while incidence remained stable, thus suggesting that survival with IPF has improved. PMID:26841042

Epidemiology of Idiopathic Pulmonary Fibrosis in Northern Italy.

PubMed

Harari, Sergio; Madotto, Fabiana; Caminati, Antonella; Conti, Sara; Cesana, Giancarlo

2016-01-01

Idiopathic pulmonary fibrosis (IPF) is the most common and severe form of idiopathic interstitial pneumonia. Despite its clinical relevance, few studies have examined the epidemiology of IPF and temporal variation in disease incidence and prevalence. Aim of the study was to investigate the prevalence, incidence and trends of IPF in Lombardy, a region with nearly 10 million inhabitants, during 2005-2010. For the identification of IPF patients, we used healthcare administrative databases of Lombardy Healthcare System and adopted three algorithms: generic, broad and narrow case definition (GCD, BCD, NCD). IPF cases were identified according to diagnoses reported in inpatient and outpatient claims occurred during 2000-2010. We estimated age- and sex-adjusted annual prevalence and incidence rates from 2005 to 2010, thus allowing for a 5-year washout period. The mean annual incidence rate was estimated at 2.3 and 5.3 per 100,000 person-years using NCD and GCD, respectively. IPF incidence was higher among males, and increased with age. Trend remained stable over the years. The estimated annual prevalence rate was 35.5, 22.4, and 12.6 per 100,000 person-years using GCD, BCD and NCD, respectively, and increased with age. Moreover, we observed a positive trend over the years. Using BCD and NCD, prevalence was higher among males. The results of this study, which is one of the largest population-based survey ever conducted according to strict criteria, indicated that prevalence of IPF increased across the years while incidence remained stable, thus suggesting that survival with IPF has improved.

Venice, Italy

NASA Image and Video Library

2002-09-24

Four hundred bridges cross the labyrinth of canals that form the 120 islands of Venice, situated in a saltwater lagoon between the mouths of the Po and Piave rivers in northeast Italy. All traffic in the city moves by boat. Venice is connected to the mainland, 4 kilometers (2.5 miles) away, by ferries as well as a causeway for road and rail traffic. The Grand Canal winds through the city for about 3 kilometers (about 2 miles), dividing it into two nearly equal sections. According to tradition, Venice was founded in 452, when the inhabitants of Aquileia, Padua, and several other northern Italian cities took refuge on the islands of the lagoon from the Teutonic tribes invading Italy at that time. This image was acquired on December 9, 2001 by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite. With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER will image Earth for the next 6 years to map and monitor the changing surface of our planet. http://photojournal.jpl.nasa.gov/catalog/PIA03860

Genomic Characterization Helps Dissecting an Outbreak of Listeriosis in Northern Italy.

PubMed

Comandatore, Francesco; Corbella, Marta; Andreoli, Giuseppina; Scaltriti, Erika; Aguzzi, Massimo; Gaiarsa, Stefano; Mariani, Bianca; Morganti, Marina; Bandi, Claudio; Fabbi, Massimo; Marone, Piero; Pongolini, Stefano; Sassera, Davide

2017-07-06

Listeria monocytogenes (Lm) is a bacterium widely distributed in nature and able to contaminate food processing environments, including those of dairy products. Lm is a primary public health issue, due to the very low infectious dose and the ability to produce severe outcomes, in particular in elderly, newborns, pregnant women and immunocompromised patients. In the period between April and July 2015, an increased number of cases of listeriosis was observed in the area of Pavia, Northern Italy. An epidemiological investigation identified a cheesemaking small organic farm as the possible origin of the outbreak. In this work we present the results of the retrospective epidemiological study that we performed using molecular biology and genomic epidemiology methods. The strains sampled from patients and those from the target farm's cheese were analyzed using PFGE and whole genome sequencing (WGS) based methods. The performed WGS based analyses included: a) in-silico MLST typing; b) SNPs calling and genetic distance evaluation; c) determination of the resistance and virulence genes profiles; d) SNPs based phylogenetic reconstruction. Three of the patient strains and all the cheese strains resulted to belong to the same phylogenetic cluster, in Sequence Type 29. A further accurate SNPs analysis revealed that two of the three patient strains and all the cheese strains were highly similar (0.8 SNPs of average distance) and exhibited a higer distance from the third patient isolate (9.4 SNPs of average distance). Despite the global agreement among the results of the PFGE and WGS epidemiological studies, the latter approach agree with epidemiological data in indicating that one the patient strains could have originated from a different source. This result highlights that WGS methods can allow to better.

Genomic Characterization Helps Dissecting an Outbreak of Listeriosis in Northern Italy

PubMed Central

Comandatore, Francesco; Corbella, Marta; Andreoli, Giuseppina; Scaltriti, Erika; Aguzzi, Massimo; Gaiarsa, Stefano; Mariani, Bianca; Morganti, Marina; Bandi, Claudio; Fabbi, Massimo; Marone, Piero; Pongolini, Stefano; Sassera, Davide

2017-01-01

Introduction Listeria monocytogenes (Lm) is a bacterium widely distributed in nature and able to contaminate food processing environments, including those of dairy products. Lm is a primary public health issue, due to the very low infectious dose and the ability to produce severe outcomes, in particular in elderly, newborns, pregnant women and immunocompromised patients. Methods In the period between April and July 2015, an increased number of cases of listeriosis was observed in the area of Pavia, Northern Italy. An epidemiological investigation identified a cheesemaking small organic farm as the possible origin of the outbreak. In this work we present the results of the retrospective epidemiological study that we performed using molecular biology and genomic epidemiology methods. The strains sampled from patients and those from the target farm's cheese were analyzed using PFGE and whole genome sequencing (WGS) based methods. The performed WGS based analyses included: a) in-silico MLST typing; b) SNPs calling and genetic distance evaluation; c) determination of the resistance and virulence genes profiles; d) SNPs based phylogenetic reconstruction. Results Three of the patient strains and all the cheese strains resulted to belong to the same phylogenetic cluster, in Sequence Type 29. A further accurate SNPs analysis revealed that two of the three patient strains and all the cheese strains were highly similar (0.8 SNPs of average distance) and exhibited a higer distance from the third patient isolate (9.4 SNPs of average distance). Discussion Despite the global agreement among the results of the PFGE and WGS epidemiological studies, the latter approach agree with epidemiological data in indicating that one the patient strains could have originated from a different source. This result highlights that WGS methods can allow to better PMID:28856063

Investigating burnout situations, nurses' stress perception and effect of a post-graduate education program in health care organizations of northern Italy: a multicenter study.

PubMed

Arrigoni, Cristina; Caruso, Rosario; Campanella, Francesca; Berzolari, Francesca Gigli; Miazza, Daniela; Pelissero, Gabriele

2015-01-01

Burnout (BO) is increasingly considered a public health problem: it is not only harmful to the individual, but also for the organization. Therefore, in recent years, research has given particular attention to the study of the phenomenon and its antecedents among the nursing profession. In the last ten years, the literature shows the prevalence of BO in different clinical settings, but there are few recent data describing the phenomenon and its relationship with educational preventive programs. The aims of this study are: a) to describe the prevalence of nurses' risk of BO in the northern Italy area b) to describe nurses' coping and their perception of the BO antecedents. c) to describe the effects of education on the nurses' coping and their recognition of BO antecedents. The study is structured into two main parts. The first was cross-sectional, the second was prospective. Burnout Potential Inventory (BPI) questionnaire was used in the cross-sectional part to survey risk of BO in three big hospitals in Northern Italy. The Health Profession Stress and Coping Scale (HPSCS) was used in the prospective part to survey the nurses' stress perception and their coping mechanisms in a post-graduate educational program. Nurses' BO risk is within the normal range, although the BPI highlighted three borderline subscales: poor team work, work overload and poor feedback. Post-graduate education had a positive effect on the stress perception, but it is not sufficient to improve coping mechanisms. The study revealed the more stressful work situations and the effect of post-graduate education to prevent the effects of stress. This topic needs further investigation in the light of the result of this study.

Lake Garda, Italy

NASA Image and Video Library

2001-07-21

This ASTER image was acquired on July 29, 2000 and covers an area of 30 by 57 km in northern Italy. Lake Garda was formed by glaciers during the last Ice Age, and is Italy's largest lake. Lago di Garda lies in the provinces of Verona, Brescia, and Trento, and is 51 kilometers (32 miles) long and from 3 to 18 kilometers (2 to 11 miles) wide. The Sarca is its chief affluent, and the lake is drained southward by the Mincio, which discharges into the Po River. Many villas are situated on its shores. On the peninsula of Sirmione, at the southern end of the lake, are the ruins of a Roman villa and a castle of the Scaligers, an Italian family of the 16th century. The RIGHT image has the land area masked out, and a harsh stretch was applied to the lake values to display variations in sediment load. Also visible are hundreds of boats and their wakes, criss-crossing the lake. The image is centered at 45.6 degrees north latitude, 10.6 degrees east longitude. http://photojournal.jpl.nasa.gov/catalog/PIA02671

Who Are the Subjects with Gambling-Related Problems Requiring Treatment? A Study in Northern Italy

PubMed Central

Fioritti, Angelo; Marani, Silvia; Gambini, Daniele; Turino, Elsa; Piazza, Antonella

2018-01-01

Background: This study analyzes data related to Hospital (HOS), Public Treatment Service Dedicated to Drug Addicts (SERD), or Community Mental Health Center (CMHC) clients with a first diagnosis of Pathological Gambling (PG) in the period 2000/2016 in Northern Italy. The aims were to describe trends and characteristics of pathological gamblers (PGs) and to estimate the prevalence of other diagnoses before or after the diagnosis of PG. Methods: Participants aged over 17 years with an ICD-9 or ICD-10 PG diagnosis were selected. Results: 680 PGs were identified, mean age 47.4 years, 20% female, 13% non-natives, 30% had other mental disorders diagnoses, 9% had alcohol dependence syndrome, and 11% had drug dependence. Most participants with comorbid disorders were diagnosed before PG, with a more elevated prevalence regarding mental disorders. Almost seven years had elapsed on average between the first admission and the diagnosis of PG. Conclusions: The results of this study highlight a growing demand for PG treatment addressed not only to SERD, but also to psychiatric and hospital services, based on the increase in SERD attendance from 2013. Many of them had already been treated for mental health problems before, but their percentage remained costant over time. PMID:29652821

Rabies and canine distemper virus epidemics in the red fox population of northern Italy (2006-2010).

PubMed

Nouvellet, Pierre; Donnelly, Christl A; De Nardi, Marco; Rhodes, Chris J; De Benedictis, Paola; Citterio, Carlo; Obber, Federica; Lorenzetto, Monica; Pozza, Manuela Dalla; Cauchemez, Simon; Cattoli, Giovanni

2013-01-01

Since 2006 the red fox (Vulpes vulpes) population in north-eastern Italy has experienced an epidemic of canine distemper virus (CDV). Additionally, in 2008, after a thirteen-year absence from Italy, fox rabies was re-introduced in the Udine province at the national border with Slovenia. Disease intervention strategies are being developed and implemented to control rabies in this area and minimise risk to human health. Here we present empirical data and the epidemiological picture relating to these epidemics in the period 2006-2010. Of important significance for epidemiological studies of wild animals, basic mathematical models are developed to exploit information collected from the surveillance program on dead and/or living animals in order to assess the incidence of infection. These models are also used to estimate the rate of transmission of both diseases and the rate of vaccination, while correcting for a bias in early collection of CDV samples. We found that the rate of rabies transmission was roughly twice that of CDV, with an estimated effective contact between infected and susceptible fox leading to a new infection occurring once every 3 days for rabies, and once a week for CDV. We also inferred that during the early stage of the CDV epidemic, a bias in the monitoring protocol resulted in a positive sample being almost 10 times more likely to be collected than a negative sample. We estimated the rate of intake of oral vaccine at 0.006 per day, allowing us to estimate that roughly 68% of the foxes would be immunised. This was confirmed by field observations. Finally we discuss the implications for the eco-epidemiological dynamics of both epidemics in relation to control measures.

A case-control study of diet and gastric cancer in northern Italy.

PubMed

La Vecchia, C; Negri, E; Decarli, A; D'Avanzo, B; Franceschi, S

1987-10-15

Dietary factors in the aetiology of stomach cancer were investigated using data from a case-control study conducted in Northern Italy on 206 histologically confirmed carcinomas and 474 control subjects in hospital for acute, non-digestive conditions, unrelated to any of the potential risk factors for gastric cancer. Dietary histories concerned the frequency of consumption per week of 29 selected food items (including the major sources of starches, proteins, fats, fibres, vitamins A and C, nitrates and nitrites in the Italian diet) and subjective scores for condiments and salt intake. Pasta and rice (the major sources of starch), polenta (a porridge made of maize) and ham were positively related with gastric cancer risk, whereas green vegetables and fresh fruit as a whole (and specifically citrus fruit) and selected fibre-rich aliments (such as whole-grain bread or pasta) showed protective effects on gastric cancer risk. Allowance for major identified potential distorting factors (chiefly indicators of socio-economic status) reduced the positive association with pasta or rice consumption, but did not appreciably modify any of the other risk estimates. When a single logistic model was fitted including all food items significant in univariate analysis, the 3 items remaining statistically significant were green vegetables (relative risk, RR = 0.27 for upper vs. lower tertile), polenta (RR = 2.32) and ham (RR = 1.60). Indices of beta-carotene and ascorbate intake were negatively and strongly related with gastric cancer risk, but the association with these micronutrients was no longer evident after simultaneous allowance for various food items. An approximately 7-fold difference in risk was found between extreme quintiles of a scale measuring major positive and negative associations.

Dynamics and conceptual model of the Rossena castle landslide (Northern Apennines, Italy)

NASA Astrophysics Data System (ADS)

Chelli, A.; Mandrone, G.; Ruffini, A.; Truffelli, G.

2005-11-01

In the Northern Apennines there are many historical villages and castles, which are of great value and represent a cultural heritage of great importance. Their presence within a territory greatly affected by landslide hazards creates, in many circumstances, the need to solve problems of land management and to act for the preservation of historical monuments. This paper describe an interesting landslide, failed during the night of 28 February 2004, that involved the village of Rossena: the failure damaged the village (Fig. 1), the road and the fields down to the stream but, fortunately, the castle just upslope the village was not involved at all. The 10th century massive castle of Rossena stands on the top of a cliff at about 500 m a.s.l., on the border between the provinces of Parma and Reggio Emilia, and it is surrounded by a small ancient village. The castle of Rossena is the best preserved stronghold of the Longobard times, enlarged and reinforced in the tenth century and partially rebuilt by Bonifacio, the father of Matilda of Canossa (the Vice-Queen of Italy and probably the most important woman in the Middle Ages) as a defensive structure guarding the Enza Valley. In addition, at Conossa, very close to Rossena, there was the meeting between Pope Gregory VII and the Emperor of Germany Henry IV, during the historical event known as "fight for the investitures". For these reasons, the area of Rossena is one of the most relevant from a historical point of view in the entire western part of the Emilia Romagna Region and it also has a high value as a geosite (Coratza et al., 2004).

Personal and occupational risk factors for carpal tunnel syndrome in meat processing industry workers in Northern Italy.

PubMed

Riccò, Matteo; Signorelli, Carlo

2017-03-24

Carpal tunnel syndrome (CTS) is a musculoskeletal condition that often impairs the fitness to work. Our aim is to retrospectively evaluate the association between physical exposures in meat processing industry in Northern Italy and the CTS, taking into account non-occupational factors. A cross-sectional study was performed to include 434 workers (236 males, 198 females, 37.0±10.6 years old, working age: 12.6±10.8 years) from meat processing industries. Signs and symptoms were collected at the compulsory occupational medical surveillance. Occupational risk factors were assessed through a questionnaire and direct assessment by investigators. Adjusted odds ratios (OR_adj) for factors of interest were estimated through binary logistic regression. Diagnosis of the CTS was reported for 61 out of 434 subjects (14.1%) for an incidence of 11.3/1000 person- years. In general, signs and symptoms for the CTS were associated with the following demographic factors: smoking history (OR = 1.909, 95% confidence interval (CI): 1.107-3.293), previous traumas of the upper limb (OR = 3.533, 95% CI: 1.743-7.165), hypothyroidism status (OR = 7.897, 95% CI: 2.917-21.38) and, in the case of female participants only, previous pregnancies (OR = 2.807, 95% CI: 1.200-6.566) as well as a personal history of oral contraceptive therapy and/or steroidal replacement therapy (OR = 11.57, 95% CI: 4.689-28.56). The carpal tunnel syndrome cases were associated with the following occupational factors (> 4 h/day): forceful hand exertion (OR_adj = 3.548, 95% CI: 1.379-9.131), repeated trauma of the hand (OR_adj = 3.602, 95% CI: 1.248- 10.395), repeated movements of the wrist (OR_adj = 2.561, 95% CI: 1.100-5.960). Increasing levels of hand activity and force were associated with the increased CTS prevalence among participants. Recommendations have to be provided in order to reduce occupational exposure to these risk factors and improve medical surveillance. Med Pr

An update of cancer mortality among chrysotile asbestos miners in Balangero, northern Italy.

PubMed Central

Piolatto, G; Negri, E; La Vecchia, C; Pira, E; Decarli, A; Peto, J

1990-01-01

The mortality experience of a cohort of chrysotile miners employed since 1946 in Balangero, northern Italy was updated to the end of 1987 giving a total of 427 deaths out of 27,010 man-years at risk. A substantial excess mortality for all causes (standardised mortality ratio (SMR) = 149) was found, mainly because of high rates for some alcohol related deaths (hepatic cirrhosis, accidents). For mortality from cancer, however, the number of observed deaths (82) was close to that expected (76.2). The SMR was raised for oral cancer (SMR 231 based on six deaths), cancer of the larynx (SMR 267 based on eight deaths), and pleura (SMR 667 based on two deaths), although the excess only reached statistical significance for cancer of the larynx. Rates were not increased for lung, stomach, or any other type of cancer. No consistent association was seen with duration or cumulative dust exposure (fibre-years) for oral cancer, but the greatest risks for laryngeal and pleural cancer were in the highest category of duration and degree of exposure to fibres. Although part of the excess mortality from laryngeal cancer is probably attributable to high alcohol consumption in this group of workers, the data suggest that exposure to chrysotile asbestos (or to the fibre balangeroite that accounts for 0.2-0.5% of total mass in the mine) is associated with some, however moderate, excess risk of laryngeal cancer and pleural mesothelioma. The absence of excess mortality from lung cancer in this cohort is difficult to interpret. Images PMID:2176805

An update of cancer mortality among chrysotile asbestos miners in Balangero, northern Italy.

PubMed

Piolatto, G; Negri, E; La Vecchia, C; Pira, E; Decarli, A; Peto, J

1990-12-01

The mortality experience of a cohort of chrysotile miners employed since 1946 in Balangero, northern Italy was updated to the end of 1987 giving a total of 427 deaths out of 27,010 man-years at risk. A substantial excess mortality for all causes (standardised mortality ratio (SMR) = 149) was found, mainly because of high rates for some alcohol related deaths (hepatic cirrhosis, accidents). For mortality from cancer, however, the number of observed deaths (82) was close to that expected (76.2). The SMR was raised for oral cancer (SMR 231 based on six deaths), cancer of the larynx (SMR 267 based on eight deaths), and pleura (SMR 667 based on two deaths), although the excess only reached statistical significance for cancer of the larynx. Rates were not increased for lung, stomach, or any other type of cancer. No consistent association was seen with duration or cumulative dust exposure (fibre-years) for oral cancer, but the greatest risks for laryngeal and pleural cancer were in the highest category of duration and degree of exposure to fibres. Although part of the excess mortality from laryngeal cancer is probably attributable to high alcohol consumption in this group of workers, the data suggest that exposure to chrysotile asbestos (or to the fibre balangeroite that accounts for 0.2-0.5% of total mass in the mine) is associated with some, however moderate, excess risk of laryngeal cancer and pleural mesothelioma. The absence of excess mortality from lung cancer in this cohort is difficult to interpret.

Phenological series in Bologna (Northern Italy): temporal trends and spatial pattern of greening

NASA Astrophysics Data System (ADS)

Puppi, Giovanna; Zanotti, Anna Letizia

2010-05-01

In Europe, in the last thirty years, the onset of spring has advanced (Estrella et al. 2009 Clim Res. 39). However the phenological shifts vary from one country to another and long time series are scanty in Southern Europe (Peňuelas et. al. 2002, Glob. Change Biol.; Črepinšek et Kajfež 2003, Ann.Ser.Hist.Nat.13): for this reason we analyzed the data on leafing of some woody species recorded during the last 3 decades (1977-2009) in the city of Bologna (Emilia-Romagna, Northern Italy) and in several hillside stations in the neighbourhood of the town. As BGS index, the average day of "first leaf unfolding" (GFI=V4, BBCH=11) of a group of common woody species was chosen: the BGS days were analysed in relation with time and temperature changes. The BGS happens on average at the end of March. The species observed display a negative trend along the period (about 2 days of advance per decade) and the BGS days show a significant correlation with the mean temperature of the period January-March (about 3 and a half days of earlier start per degree of increasing temperature). Since an increase in winter temperatures has been predicted in the Emilia-Romagna region in the next decades (Tomozeiu et al. 2007, Theor. Appl. Climatol. 90), the growing season in our region is probably going to extend. Phenological spatial patterns of the neighbourhood of the city are also analysed: greening generally starts on southfacing hills between 100 and 300 m asl.

Multi-disciplinary dating of a baked clay kiln excavated at Chieri, Northern Italy

NASA Astrophysics Data System (ADS)

Tema, Evdokia; Fantino, Fulvio; Ferrara, Enzo; Lo Giudice, Alessandro; Re, Alessandro; Barello, Federico; Vella, Silvia; Cirillo, Luigi; Gulmini, Monica

2014-05-01

A combined archaeological, archaeomagnetic and thermoluminescence study has been carried out on a rescue excavation kiln, discovered at Chieri, Northern Italy. Rock magnetic experiments indicate the dominance of a low coercivity magnetic phase, such as magnetite and/or Ti-magnetite as the main carrier of the remanent magnetization. Stepwise thermal demagnetization experiments generally show a stable characteristic remanent magnetization (ChRM). The mean archaeomagnetic direction, calculated from 17 independently oriented samples, is D=18.2o, I=66.8o with α95=2.6o and k=184. Archaeomagnetic dating of the kiln has been obtained after comparison of the kiln's ChRM direction with the reference curves produced by the SHA.DIF.3K European regional geomagnetic field model. Independent dating of the kiln has also been obtained from thermoluminescence (TL) study of two baked clay samples coming from the kiln's walls. The environmental dose has been measured in situ using field dosimeters. Accurate TL procedures have been followed for the calculation of annual dose and eventually the TL age. The combination of the archaeological evidence, archaeomagnetic and TL datings suggest that the last usage of the kiln occurred around the 17th century AD. Comparison of the results obtained from the different methods shows the relevant potential of these techniques on dating of baked clay artefacts; yet it also highlights the range of uncertainty sources affecting measurements, related to the samples and/or to the environment, and the utility of dating cross-checking for obtaining reliable dates.

Pattern of susceptibility to measles in Italy. Serological Study Group.

PubMed Central

Salmaso, S.; Gabutti, G.; Rota, M. C.; Giordano, C.; Penna, C.; Mandolini, D.; Crovari, P.

2000-01-01

On the basis of seroprevalence and incidence data we describe the distribution of individuals susceptible and immune to measles in Italy in 1996-97. In regions where vaccination coverage was at least 70%, approximately 10% of 3-year-old children were susceptible to measles, whereas 40% were in this category in regions with lower vaccination coverage. Seroprevalence among children older than 4 years was similar for the two groups of regions; in the age group 20-39 years it was approximately 95%. During 1990-96 in the regions with lower vaccination coverage the incidence was highest among children aged 4-6 years, and the median age of cases was 7 years; in the regions with higher vaccination coverage, however, the incidence remained at around 5% for the age group 4-16 years, and the overall median age was 10 years. These data confirm the partial reduction in measles incidence in Italy, although transmission has still not been interrupted. The size and geographical distribution of the current pool of susceptible individuals can be expected to present an obstacle to measles elimination if appropriate vaccination strategies, such as catch-up campaigns, are not adopted. PMID:10994277

Present vertical movements in Central and Northern Italy from GPS data: Possible role of natural and anthropogenic causes

NASA Astrophysics Data System (ADS)

Cenni, N.; Viti, M.; Baldi, P.; Mantovani, E.; Bacchetti, M.; Vannucchi, A.

2013-11-01

Insights into the present vertical kinematic pattern in Central and Northern Italy are gained by the analysis of GPS data acquired by a network of 262 permanent stations, working over various time intervals since 2001. Uplift is observed in the Alps (up to 5 mm/yr) and Apennines (1-2 mm/yr), whereas subsidence is recognized in the southern Venetian Plain (2-4 mm/yr) and the eastern Po Valley, where the highest rates are observed (up to 9 mm/yr between Reggio Emilia and Rimini). On the other hand, the western part of the Po Valley presents very low vertical rates. The boundary between subsiding and not subsiding Po Valley nearly corresponds to the Giudicarie tectonic discontinuity. It is argued that the different kinematic patterns of the eastern and western Padanian sectors may also be related to the underthrusting of the eastern domain beneath the western one. Some considerations are then reported on how the various causes of vertical movements (tectonic and sedimentological processes) may contribute to the observed kinematics.

The Development of the Humanistic Curriculum in Fifteenth-Century Italy.

ERIC Educational Resources Information Center

Grendler, Paul F.

One of the major changes in educational practices occurred during the Italian Renaissance, when a system of pre-university education based on a thorough grounding in the Latin, and to a lesser extent, the Greek classics began. This change started in early 15th century northern Italy and lasted until well into the 20th century. Italian school…

Prevalence of latent tuberculosis infection in healthcare workers at a hospital in Naples, Italy, a low-incidence country.

PubMed

Lamberti, Monica; Muoio, Mariarosaria; Arnese, Antonio; Borrelli, Sharon; Di Lorenzo, Teresa; Garzillo, Elpidio Maria; Signoriello, Giuseppe; De Pascalis, Stefania; Coppola, Nicola; Nienhaus, Albert

2016-01-01

Healthcare workers (HCWs) are at higher risk than the general population of contracting tuberculosis (TB). Moreover, although subjects with latent TB infection (LTBI) are asymptomatic and are not infectious, they may eventually develop active disease. Thus, a fundamental tool of TB control programs for HCWs is the screening and treatment of LTBI. From January 2014 to January 2015, hospital personnel at Azienda Ospedaliera Universitaria, Naples, Italy, were screened for TB. To this end, a tuberculin skin test (TST) was administered as an initial examination, unless when contraindicated, in which case the QuantiFERON® TB-Gold (QFT) assay was performed. Moreover, QFT was carried out on all TST-positive cases to confirm the initial result. Of 628 personnel asked to participate, 28 (4.5%) denied consent, 533 were administered TST as the baseline examination, and 67 were tested only with QFT. In the TST group, 73 (13.2%) individuals were found positive, 418 (78.4%) were negative, and 42 (7.9%) were absent for the reading window; QFT confirmed the result in 39 (53.4%) TST-positive individuals. In the QFT-only group, 44 (65.7%) individuals were found positive. All TST- and/or QFT-positive subjects were referred for chest X-ray and examination by an infectious diseases specialist. None were found to have active TB, and were thus diagnosed with LTBI. Although Italy is a low-incidence country regarding TB, our findings suggest that the prevalence of LTBI in HCWs may be relatively high. As a result, active screening for TB and LTBI is needed for these workers.

Stroke incidence is decreasing in whites but not in blacks: a population-based estimate of temporal trends in stroke incidence from the Greater Cincinnati/Northern Kentucky Stroke Study.

PubMed

Kleindorfer, Dawn O; Khoury, Jane; Moomaw, Charles J; Alwell, Kathleen; Woo, Daniel; Flaherty, Matthew L; Khatri, Pooja; Adeoye, Opeolu; Ferioli, Simona; Broderick, Joseph P; Kissela, Brett M

2010-07-01

Although other studies (in largely white populations) have found that stroke incidence declined during the 1990s, we previously reported that stroke incidence in our population (18% of which was black) did not change during that decade and that incidence rates in blacks were significantly higher than in whites. We sought to update temporal trends in stroke incidence by adding new data obtained from our large, biracial population in 2005. The objective of this study was to examine temporal trends in stroke incidence and case-fatality within a large biracial population over time by comparing stroke incidence rates from 1993 to 1994, 1999, and 2005. Within the Greater Cincinnati/Northern Kentucky population of 1.3 million, all strokes among area residents were ascertained at all local hospitals during July 1993 to June 19/94 and calendar years 1999 and 2005. A sampling scheme was used to ascertain cases in the out-of-hospital setting. Only first-ever strokes were included in this analysis. Race-specific incidence rates, standardized to the 2000 US Census population, and case-fatality rates were calculated. The number of physician-confirmed first-ever strokes in patients >or=20 years of age was 1942 in 1993 to 1994, 2041 in 1999, and 1921 in 2005. In all study periods, blacks had higher stroke incidence than whites, and case-fatality rates were similar between races. In contrast to previous study periods, we found a significant decrease in overall stroke incidence in 2005. When stratified by race and stroke subtype, this change was driven by a decrease in ischemic stroke incidence among whites, whereas ischemic stroke incidence in blacks was unchanged. Hemorrhagic stroke incidence was unchanged in both races. For the first time, we report a significant decrease in stroke incidence within our population, which is consistent with other reports in the literature. This decrease was found only among whites, which suggests a worsening of the racial disparity in stroke

Stroke Incidence is Decreasing in Whites, but Not in Blacks: A Population-Based Estimate of Temporal Trends in Stroke Incidence from the Greater Cincinnati/Northern Kentucky Stroke Study

PubMed Central

Kleindorfer, Dawn; Khoury, Jane; Moomaw, Charles J.; Alwell, Kathleen; Woo, Daniel; Flaherty, Matthew L.; Khatri, Pooja; Adeoye, Opeolu; Ferioli, Simona; Broderick, Joseph P.; Kissela, Brett M.

2010-01-01

Context While other studies (in largely white populations) have found that stroke incidence declined during the 1990s, we previously reported that stroke incidence in our population (18% of which was black) did not change during that decade and that incidence rates in blacks were significantly higher than in whites. We sought to update temporal trends in stroke incidence by adding new data obtained from our large, bi-racial population in 2005. Objective To examine temporal trends in stroke incidence and case fatality within a large, biracial population over time, by comparing stroke incidence rates from 1993/94, 1999, and 2005. Design, Setting, and Participants Within the Greater Cincinnati/Northern Kentucky population of 1.3 million, all strokes among area residents were ascertained at all local hospitals during 7/93-6/94 and calendar years 1999 and 2005. A sampling scheme was used to ascertain cases in the out-of-hospital setting. Only first-ever strokes were included in this analysis. Race-specific incidence rates, standardized to the 2000 U.S. Census population, and case-fatality rates were calculated. Results The number of physician-confirmed first-ever strokes in patients ≥20 years of age was 1,942 in 1993/94, 2,041 in 1999, and 1,921 in 2005. In all study periods, blacks had higher stroke incidence than whites, and case fatality rates were similar between races. In contrast to previous study periods, we found a significant decrease in overall stroke incidence in 2005. When stratified by race and stroke subtype, this change was driven by a decrease in ischemic stroke incidence among whites, while ischemic stroke incidence in blacks was unchanged. Hemorrhagic stroke incidence was unchanged in both races. Discussion For the first time, we report a significant decrease in stroke incidence within our population, which is consistent with other reports in the literature. This decrease was found only among whites, which suggests a worsening of the racial disparity

Soapstones from the Ossola Valley (Piedmont, northern Italy)

NASA Astrophysics Data System (ADS)

Cavallo, Alessandro

2017-04-01

The term "soapstones" is referred to "soft", easily workable stones (talc and/or chlorite-rich metamorphic rocks, deriving from mafic - ultramafic protoliths), typically used for jars, pots and pipes. The term has been also improperly extended to "harder" varieties (e.g. serpentinites), mostly suitable for roof slabs and millstones. These rocks are characterized by easy workability and fire-resistance, and they had a remarkable historical, artistic and archaeological importance. In the Ossola region (Piedmont, northern Italy), the soapstones are traditionally known as "Pietra Laugera", "Pietra Lavizzaria" or "Pietra Ollare", and represent one of the oldest stony raw materials used since the Bronze Age (archaeological find in the Toceno surroundings, Vigezzo Valley). The discovery of archaeological handmade objects in the surroundings of the Ossola Valley testifies a massive use of green stones during the I century A.D., even for cinerary urns and grave outfits. A lot of two handles pots and milk vessels date back to the Middle Ages, as well as millstones and water pipes. Artistic and ornamental uses are documented in churches and civil buildings: for example, columns, capitals, pilasters and bas-reliefs (Sacro Monte del Calvario chapels, now UNESCO heritage, and the Collegiale Church in Domodossola) as well as fireplaces (e.g. Silva Palace in Domodossola), sculptures, ornaments and balustrades. The productivity reached the top in the XIX century and stopped in the twenties; nowadays the extraction occurs only in the Loana Valley, with a very limited production. The historical soapstones derive both from ophiolitic complexes (Antrona and Zermatt-Saas Zones) and from the ultramafic complexes within the Orselina-Moncucco-Isorno Zone, Monte Leone nappe and Sesia-Lanzo Zone. The historical quarries are usually small (even erratic boulders), and scattered over many lateral valleys, such as Brevettola, Antrona, Bognanco and Loana. A total of 52 representative samples were

Polychlorinated Biphenyls, Glycaemia and Diabetes in a Population Living in a Highly Polychlorinated Biphenyls-Polluted Area in Northern Italy: a Cross-sectional and Cohort Study

PubMed Central

Zani, Claudia; Donato, Francesco; Magoni, Michele; Feretti, Donatella; Covolo, Loredana; Vassallo, Francesco; Speziani, Fabrizio; Scarcella, Carmelo; Bergonzi, Roberto; Apostoli, Pietro

2013-01-01

Conflicts of interests: the authors declare no potential conflict of interests. Background Polychlorinated biphenyls (PCBs) have been found to be associated with diabetes in some, but not all, studies performed so far. The aim of this study was to assess the association between PCB serum levels and glycaemia and diabetes in people living in Brescia, a highly industrialised PCB-polluted town in Northern Italy. Design and Methods 527 subjects were enrolled in a cross-sectional population-based study: they were interviewed face-to-face in 2003 and also provided a blood sample under fasting conditions. The concentration of 24 PCB congeners was determined using gas-chromatography (GC/MS). Subsequently, all subjects were included in a follow-up (cohort) study. According to the Local Health Authority health-care database, subjects were considered to be diabetic if they had diabetes at interview time (prevalent cases) or during a 7-year follow-up (incident cases). Results A total of 53 subjects (10.0%) were diabetics: 28 had diabetes at enrolment and other 25 developed the disease subsequently. Diabetes frequency increased according to the serum concentrations of total PCBs and single PCB congeners, but no association was found when estimates were adjusted for education, body mass index, age and gender by logistic regression analysis. Accordingly, glycaemia increased with PCB serum levels, but no association was observed when multiple regression analysis, including confounding factors, was performed. Conclusions This study does not support the hypothesis that PCB environmental exposure is strictly associated with diabetes or glycaemia. PMID:25170473

Coastal evolution and littoral cells distribution in Northern Tuscany (Italy)

NASA Astrophysics Data System (ADS)

Anfuso, Giorgio; Pranzini, Enzo; Vitale, Giovanni

2010-05-01

This paper deals with a 64-km-long coastal physiographic unit located in the northern littoral of Tuscany (Italy). The investigated area recorded important erosion problems in last century due to the reduction in sediment input from rivers and to the feeding effect of ports and shore protection structures. Vertical aerial photographs and direct field surveys (with RTK-GPS and total station) were used for the reconstruction of coastline changes at medium-long temporal scales. The littoral is a microtidal environment and most frequent and severe storms approach from the 245° direction, with maximum one year recurrence Hs values between 3.5 and 4.0 m, less frequent and severe storms approach from the 180° and 200° directions. Concerning coastal evolution for the 1938-2005 period, important accretion was recorded updrift of two harbours (300 at Viareggio and 100 m at Carrara port in a convergence area (100 m at Marina di Pietrasanta), whereas severe erosion occurred downcoast of Carrara harbour (-130 m at Marina dei Ronchi) and at the northern (unprotected) side of the Arno River mouth (with maximum values of 400 m). Locally breakwaters and groins were implemented to solve erosion problems but the structures only - and not always - solved problems at local scale shifting erosion downdrift. Coastal compartmentalisation controlled the longshore distribution of erosion/accretion patterns and it was strongly forced by natural and human structures and coastal orientation in relation to wave approaching fronts. Three main littoral cells were formed by four natural limits: i) Punta Bianca Promontory, which works as a fixed absolute limit; ii) Marina di Pietrasanta, a convergent, free limit; iii) the Arno River Mouth, a divergent limit; and, iv) Livorno harbour, which works as an absolute fixed southern limit. In it is important to highlight that human structures interfere with natural sediment transport within major cells creating small sub-cells. This way, the general

[Managing patients with prostate cancer in Italy during the first year after diagnosis. A cost description based on a sample of 8 urological wards].

PubMed

Lazzaro, Carlo

2003-09-01

The aim of the paper is to report of an empirical retrospective study (1994-1999) on the cost of managing patient with prostate cancer (PC) during the first year after diagnosis in Italy. In January 2000, a questionnaire on qualitative, quantitative and economic data concerning the clinical path expected for patients with PC (diagnosis; staging; follow-up; drug; surgery; chemotherapy and radiotherapy) was sent to 14 Italian urological wards (UWs), 5 school of medicine-based (Northern Italy: 2; Central Italy: 1; Southern Italy: 2), 4 self-governing hospital-based (Northern Italy: 1; Southern Italy: 3), 5 Health Authorities hospital-based (Northern Italy: 2; Central Italy: 2; Southern Italy: 1). UWs were expected to contribute to analysis with 15 patients' records per year each, for a total amount of 1.260 filled questionnaires. Only medical costs related to patient management have been considered; hospitals and Health Authorities overheads were not taken into account. A cost description was performed considering the hospital viewpoint. We received 416 out of 1.260 expected questionnaires (redemption rate: 33%) from 8 out of 14 UWs: 2 school of medicine-based (Central Italy: 1; Southern Italy: 1); 2 self-governing hospital-based (Southern Italy: 2); 4 Health Authorities hospital-based (Northern Italy: 1; Central Italy: 3). Only 411 out of 416 questionnaires were included in data analysis. Patients' average age at the time of diagnosis was 74.1 years (range: 68.6-76.7). A moderate percentage of neoplasms in patients' relatives was reported (17.8%; 5.6% for PC). The average cost per patient with CP during the first year after diagnosis was Euro 6,575.31 (range: Euro 5,035.65-Euro 12,367.69). The cost-driver was drug therapy (43.07%), followed by surgery (26.41%), diagnosis (12.39%), staging (8.58%); follow-up (8.25%) and radiotherapy (1.30%); no data on chemotherapy was reported. Diagnosis, staging and follow-up tests and procedures were performed mainly in outpatient

Inverse occurrence of cancer and Alzheimer disease: a population-based incidence study.

PubMed

Musicco, Massimo; Adorni, Fulvio; Di Santo, Simona; Prinelli, Federica; Pettenati, Carla; Caltagirone, Carlo; Palmer, Katie; Russo, Antonio

2013-07-23

To evaluate the incidence of cancer in persons with Alzheimer disease (AD) and the incidence of AD dementia in persons with cancer. This was a cohort study in Northern Italy on more than 1 million residents. Cancer incidence was derived from the local health authority (ASL-Mi1) tumor registry and AD dementia incidence from registries of drug prescriptions, hospitalizations, and payment exemptions. Expected cases of AD dementia were calculated by applying the age-, sex-, and calendar year-specific incidence rates observed in the whole population to the subgroup constituted of persons with newly diagnosed cancers during the observation period (2004-2009). The same calculations were carried out for cancers in patients with AD dementia. Separate analyses were carried out for the time period preceding or following the index diagnosis for survivors and nonsurvivors until the end of 2009 and for different types and sites of cancer. The risk of cancer in patients with AD dementia was halved, and the risk of AD dementia in patients with cancer was 35% reduced. This relationship was observed in almost all subgroup analyses, suggesting that some anticipated potential confounding factors did not significantly influence the results. The occurrence of both cancer and AD dementia increases exponentially with age, but with an inverse relationship; older persons with cancer have a reduced risk of AD dementia and vice versa. As AD dementia and cancer are negative hallmarks of aging and senescence, we suggest that AD dementia, cancer, and senescence could be manifestations of a unique phenomenon related to human aging.

In A Queer Place in Time: Fictions of Belonging in Italy 1890-2010

NASA Astrophysics Data System (ADS)

Atwood, Christopher Burke

In a Queer Place in Time: Fictions of Belonging in Italy 1890-2010 maps the "elsewheres"---spatial, temporal and intertextual--- that authorize same-sex desire in modern Italy. Tracing a genealogy that spans from nineteenth century travel writing about Italy to contemporary Italian novels, I argue that texts exported from the Northern Europe and the U.S. function as vital site of affiliation and vexing points of discrepancy for Italy's queers. Pier Vittorio Tondelli's Camere separate (1989), for instance, cites the British novelist Christopher Isherwood as proof that -- somewhere else -- silence did not yoke homosexuality. Rather than defining sexuality as a constant set of desires, I demonstrate it to be a retroactive fiction. It is the fleeting affinity that the reading of inherited texts can evoke. In examining the reception of transnational gay narratives in the national context of Italy, this dissertation argues that the concept of "Western" homosexuality is internally riven. Ultimately, In a Queer Place in Time illuminates how local histories -- including affective differences like shame, estrangement and backwardness -- continue to haunt gay culture's global fictions. !

Veneto Region, Italy. Health system review.

PubMed

Toniolo, Franco; Mantoan, Domenico; Maresso, Anna

2012-01-01

The Health Systems in Transition (HiT) profiles are country-based reports that provide a detailed description of a health system and of policy initiatives in progress or under development. This HiT is one of the first to be written on a subnational level of government and focuses on the Veneto Region of northern Italy. HiTs examine different approaches to the organization, financing and delivery of health services and the role of the main actors in health systems; describe the institutional framework, process, content and implementation of health and health care policies; and highlight challenges and areas that require more in-depth analysis. The Veneto Region is one of Italy's richest regions and the health of its resident population compares favourably with other regions in Italy. Life expectancy for both men and women, now at 79.1 and 85.2 years, respectively, is slightly higher than the national average, while mortality rates are comparable to national ones. The major causes of death are tumours and cardiovascular diseases. Under Italy's National Health Service, the organization and provision of health care is a regional responsibility and regions must provide a nationally defined (with regional input) basic health benefit package to all of their citizens; extra services may be provided if budgets allow. Health care is mainly financed by earmarked central and regional taxes, with regions receiving their allocated share of resources from the National Health Fund. Historically, health budget deficits have been a major problem in most Italian regions, but since the early 2000s the introduction of efficiency measures and tighter procedures on financial management have contributed to a significant decrease in the Veneto Regions health budget deficit.The health system is governed by the Veneto Region government (Giunta) via the Departments of Health and Social Services, which receive technical support from a single General Management Secretariat. Health care is

Wide recognition of Culex pipiens and lack of detection of Culex torrentium through biomolecular differentiation of mosquitoes in the Emilia-Romagna region, Northern Italy.

PubMed

Calzolari, M; Bonilauri, P; Bellini, R; Becker, S; Dottori, M

2016-12-01

The Culex pipiens complex includes species with reported differences in vector competence for arthropod-borne viruses, many of which are of significant importance to human health such as the West Nile virus and the Sindbis virus. This group of mosquitoes is difficult to distinguish morphologically; particularly as adult females. In Europe, the two species of the complex, Culex pipiens Linnaeus 1758 and Culex torrentium Martini 1925, are often found sympatrically. With the aim to characterize the presence and spread of both species in the Emilia-Romagna region, Northern Italy, mosquitoes of the complex - collected during the West Nile virus surveillance plans - were tested by multiplex real-time PCR for the detection of the two species Cx. pipiens and Cx. torrentium. A total of 24 165 mosquitoes, collected between 2012 and 2014 from 105 sites, and sorted in 204 pools, were tested. All tested pools were found to be composed of Cx. pipiens, whereas Cx. torrentium was not detected. These results indicate a likely absence of Cx. torrentium mosquitoes within the surveyed territory, whereas Cx. pipiens is widely distributed in the area mentioned. This is in line with previous reports, which describe a pre-alpine distribution of Cx. torrentium in Italy. © 2016 The Royal Entomological Society.

Reducing time delays in the management of ischemic stroke patients in Northern Italy.

PubMed

Vidale, Simone; Arnaboldi, Marco; Bezzi, Giacomo; Bono, Giorgio; Grampa, Giampiero; Guidotti, Mario; Perrone, Patrizia; Salmaggi, Andrea; Zarcone, Davide; Zoli, Alberto; Agostoni, Elio

2016-07-15

Thrombolysis represents the best therapy for ischemic stroke but the main limitation of its administration is time. The avoidable delay is a concept reflecting the effectiveness of management pathway. For this reason, we projected a study concerning the detection of main delays with following introduction of corrective factors. In this paper we describe the results after these corrections. Consecutive patients admitted for ischemic stroke during a 3-months period to 35 hospitals of a macro-area of Northern Italy were enrolled. Each time of management was registered, identifying three main intervals: pre-hospital, in-hospital and total times. Previous corrective interventions were: 1.increasing of population awareness to use the Emergency Medical Service (EMS); 2.pre-notification of Emergency Department; 3.use of high urgency codes; 4.use of standardised operational algorithm. Statistical analysis was conducted using time-to-event analysis and Cox proportional hazard regression. 1084 patients were enrolled. EMS was alerted for 56.3% of subjects, mainly in females and severe strokes (p<0.001). Thrombolytic treatment was performed in 4.7% of patients. Median pre-hospital and in-hospital times were 113 and 105min, while total time was 240. High urgency codes at transport contributed to reduce pre-hospital and in-hospital time (p<0.05). EMS use and high urgency codes promoted thrombolysis. Treatment within 4.5hours from symptom onset was performed in 14% of patients more than the first phase of study. The implementation of an organizational system based on EMS and concomitant high urgency codes use was effective to reduce avoidable delay and to increase thrombolysis. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Dietary exposure estimates of twenty-one trace elements from a Total Diet Study carried out in Pavia, Northern Italy.

PubMed

Turconi, Giovanna; Minoia, Claudio; Ronchi, Anna; Roggi, Carla

2009-04-01

The significant role of trace elements in human health is well documented. Trace elements are those compounds that need to be present in the human diet to maintain normal physiological functions. However, some microelements may become harmful at high levels of exposure, or, on the other hand, may give rise to malnutrition, when their exposure is too low. The aim of the present study was to provide a reliable estimate of the dietary exposure of twenty-one trace elements in a Northern Italian area. For this purpose, trace element analyses were undertaken on total diet samples collected from a university cafeteria in Pavia, Northern Italy. The average daily exposure for the adult people was calculated on the basis of food consumption frequency, portion size and trace element levels in foodstuffs. The mean exposure values satisfy the Italian RDA for all the essential trace elements, except for Fe exposure in females, and are well below the Provisional Tolerable Daily Intake for all the toxic compounds, showing that the probability of dietary exposure to health risks is overall small. As far as Fe exposure is concerned, a potential risk of anaemia in the female adult population should be considered, then studies aimed at evaluating the Fe nutritional status of adult Italian women should be addressed. In conclusion, while not excluding the possibility that the daily exposure determined in the present study may not be representative of the population as a whole, this study provides a good estimate of the Italian adult consumer exposure to twenty-one trace elements.

Developing a model for the mercury cycle in the Marano-Grado Lagoon (Italy)

EPA Science Inventory

The Marano-Grado Lagoon is a wetland system of about 160 km2 located in the Northern Adriatic Sea (Italy) between the Tagliamento and the Isonzo River mouths. The lagoon morphology and biogeochemistry are primarily controlled by the exchange with the Adriatic Sea and, to a lesser...

Regional geographic variations in kidney cancer incidence rates in European countries.

PubMed

Li, Peng; Znaor, Ariana; Holcatova, Ivana; Fabianova, Eleonora; Mates, Dana; Wozniak, Magdalena B; Ferlay, Jacques; Scelo, Ghislaine

2015-06-01

Marked unexplained national variations in incidence rates of kidney cancer have been observed for decades in Europe. To investigate geographic variations at the regional level and identify European regions with high incidence rates of kidney cancer. Regional- and national-level incidence data were extracted from the Cancer Incidence in Five Continents databases, local cancer registry databases, and local published reports. World population age-standardised rates (ASRs) were calculated for the periods 2003-2007 and 1988-1992. Rates by period and sex were compared using map visualisation. During 2003-2007, the highest ASR was found in the Plzen region, Czech Republic (31.4/100,000 person-years in men). Other regions of the Czech Republic had ASRs of 18.6-27.5/100,000 in men, with a tendency for higher rates in regions south of Prague. Surrounding regions, including eastern Germany and regions of Slovakia and Austria, had medium-to-high incidence rates (13.0-16.8/100,000 in men). Three other areas in Europe showed higher incidence rates in men compared with the rest of the continent: Lithuania, Estonia, Latvia, and Belarus (15.0-17.6/100,000); Iceland (13.5/100,000), and northern Italy (up to 16.0/100,000). Similar regional differences were observed among women, with rates approximately half of those observed in men in the same region. In general, these regional geographic variations remained stable over the periods 1988-1992 and 2003-2007, although higher incidence rates were detected in the Baltic countries in 2003-2007. Several European regions show particularly high rates of kidney cancer incidence. Large variations were observed within countries covered by national health-care systems, implying that overdetection is not the major factor. We present regional geographic variations in kidney cancer incidence rates in Europe. We highlight several regions with high incidence rates where further studies should be conducted for cancer control and prevention. Copyright �

Cancer incidence in northern Sweden before and after the Chernobyl nuclear power plant accident.

PubMed

Alinaghizadeh, Hassan; Tondel, Martin; Walinder, Robert

2014-08-01

Sweden received about 5 % of the total release of (137)Cs from the Chernobyl nuclear power plant accident in 1986. The distribution of the fallout mainly affected northern Sweden, where some parts of the population could have received an estimated annual effective dose of 1-2 mSv per year. It is disputed whether an increased incidence of cancer can be detected in epidemiological studies after the Chernobyl nuclear power plant accident outside the former Union of Soviet Socialist Republics. In the present paper, a possible exposure-response pattern between deposition of (137)Cs and cancer incidence after the Chernobyl nuclear power plant accident was investigated in the nine northernmost counties of Sweden (2.2 million inhabitants in 1986). The activity of (137)Cs from the fallout maps at 1986 was used as a proxy for the received dose of ionizing radiation. Diagnoses of cancer (ICD-7 code 140-209) from 1980 to 2009 were received from the Swedish Cancer Registry (273,222 cases). Age-adjusted incidence rate ratios, stratified by gender, were calculated with Poisson regression in two closed cohorts of the population in the nine counties 1980 and 1986, respectively. The follow-up periods were 1980-1985 and 1986-2009, respectively. The average surface-weighted deposition of (137)Cs at three geographical levels; county (n = 9), municipality (n = 95) and parish level (n = 612) was applied for the two cohorts to study the pre- and the post-Chernobyl periods separately. To analyze time trends, the age-standardized total cancer incidence was calculated for the general Swedish population and the population in the nine counties. Joinpoint regression was used to compare the average annual percent change in the general population and the study population within each gender. No obvious exposure-response pattern was seen in the age-adjusted total cancer incidence rate ratios. A spurious association between fallout and cancer incidence was present, where areas with the

Inorganic raw materials economy and provenance of chipped industry in some stone age sites of northern and central Italy.

PubMed

Bietti, Amilcare; Boschian, Giovanni; Crisci, Gino Mirocle; Danese, Ermanno; De Francesco, Anna Maria; Dini, Mario; Fontana, Federica; Giampietri, Alessandra; Grifoni, Renata; Guerreschi, Antonio; Liagre, Jérémie; Negrino, Fabio; Radi, Giovanna; Tozzi, Carlo; Tykot, Robert

2004-06-01

An opportunistic and local choice of raw materials is typically attested in the Lower and Middle Paleolithic industries throughout Italy. The quality of the raw material usually affected the flaking technology and quality of the products. In the Upper Paleolithic and the Mesolithic, raw material procurement strategies were more complex. Flint was exploited both locally, in areas where abundant outcrops of raw materials were available (such as the Lessini mountains), and in distant localities, after which it was transported or exchanged over medium/long distances. Different routes of exchange were thus followed in the various periods; good reconstruction of these routes have been provided by a study of the Garfagnana sites in Northern Tuscany, and the Mesolithic deposit of Mondeval de Sora (Dolomites). An interesting example of a Late Upper Paleolithic flint quarry and workshop were found in Abruzzo, in the San Bartolomeo shelter. The extended trade of obsidian from Lipari, Palmarola and Sardinia to the Italian Peninsula is attested in the Neolithic, with some differences concerning the age and different areas.

High-resolution shallow reflection seismic image and surface evidence of the Upper Tiber Basin active faults (Northern Apennines, Italy)

USGS Publications Warehouse

Donne, D.D.; Plccardi, L.; Odum, J.K.; Stephenson, W.J.; Williams, R.A.

2007-01-01

Shallow seismic reflection prospecting has been carried out in order to investigate the faults that bound to the southwest and northeast the Quaternary Upper Tiber Basin (Northern Apennines, Italy). On the northeastern margin of the basin a ??? 1 km long reflection seismic profile images a fault segment and the associated up to 100 meters thick sediment wedge. Across the southwestern margin a 0.5 km-long seismic profile images a 50-55??-dipping extensional fault, that projects to the scarp at the base of the range-front, and against which a 100 m thick syn-tectonic sediment wedge has formed. The integration of surface and sub-surface data allows to estimate at least 190 meters of vertical displacement along the fault and a slip rate around 0.25 m/kyr. Southwestern fault might also be interpreted as the main splay structure of regional Alto Tiberina extensional fault. At last, the 1917 Monterchi earthquake (Imax=X, Boschi et alii, 2000) is correlable with an activation of the southwestern fault, and thus suggesting the seismogenic character of this latter.

Potential SRF generation from a closed landfill in northern Italy.

PubMed

Passamani, Giorgia; Ragazzi, Marco; Torretta, Vincenzo

2016-01-01

The aim of this work is to assess the possibility of producing solid recovered fuel (SRF) and "combustible SRF" from a landfill located in the north of Italy, where the waste is placed in cylindrical wrapped bales. Since the use of landfills for the disposal of municipal solid waste has many technical limitations and is subject to strict regulations and given that landfill post-closure care is very expensive, an interesting solution is to recover the bales that are stored in the landfill. The contents of the bales can then be used for energy recovery after specific treatments. Currently the landfill is closed and the local municipal council together with an environmental agency are considering constructing a mechanical biological treatment (MBT) plant for SRF production. The municipal solid waste that is stored in the landfill, the bio-dried material produced by the hypothetically treated waste in a plant for bio-drying, and the SRF obtained after the post-extraction of inert materials, metals and glass from the bio-dried material were characterized according to the quality and classification criteria of regulations in Italy. The analysis highlighted the need to treat the excavated waste in a bio-drying plant and later to remove the inert waste, metals and glass. Thus in compliance with Italian law, the material has a high enough LHV to be considered as "combustible SRF", (i.e. an SRF with enhanced characteristics). Copyright © 2015 Elsevier Ltd. All rights reserved.

Rabies and Canine Distemper Virus Epidemics in the Red Fox Population of Northern Italy (2006–2010)

PubMed Central

De Benedictis, Paola; Citterio, Carlo; Obber, Federica; Lorenzetto, Monica; Pozza, Manuela Dalla; Cauchemez, Simon; Cattoli, Giovanni

2013-01-01

Since 2006 the red fox (Vulpes vulpes) population in north-eastern Italy has experienced an epidemic of canine distemper virus (CDV). Additionally, in 2008, after a thirteen-year absence from Italy, fox rabies was re-introduced in the Udine province at the national border with Slovenia. Disease intervention strategies are being developed and implemented to control rabies in this area and minimise risk to human health. Here we present empirical data and the epidemiological picture relating to these epidemics in the period 2006–2010. Of important significance for epidemiological studies of wild animals, basic mathematical models are developed to exploit information collected from the surveillance program on dead and/or living animals in order to assess the incidence of infection. These models are also used to estimate the rate of transmission of both diseases and the rate of vaccination, while correcting for a bias in early collection of CDV samples. We found that the rate of rabies transmission was roughly twice that of CDV, with an estimated effective contact between infected and susceptible fox leading to a new infection occurring once every 3 days for rabies, and once a week for CDV. We also inferred that during the early stage of the CDV epidemic, a bias in the monitoring protocol resulted in a positive sample being almost 10 times more likely to be collected than a negative sample. We estimated the rate of intake of oral vaccine at 0.006 per day, allowing us to estimate that roughly 68% of the foxes would be immunised. This was confirmed by field observations. Finally we discuss the implications for the eco-epidemiological dynamics of both epidemics in relation to control measures. PMID:23630599

A 2-yr Mosquito Survey Focusing on Aedes koreicus (Diptera: Culicidae) in Northern Italy and Implications for Adult Trapping.

PubMed

Baldacchino, F; Montarsi, F; Arnoldi, D; Barategui, C; Ferro Milone, N; Da Rold, G; Capelli, G; Rizzoli, A

2017-05-01

Aedes koreicus (Edwards) is an invasive mosquito species, like Aedes albopictus (Skuse) and Aedes japonicus japonicus (Theobald), that has already colonized a large part of northeastern Italy and other European countries. Despite its rapid expansion, information about adult distribution and trapping is lacking. Here, we conducted a 2-yr longitudinal survey using adult traps to investigate the spatiotemporal distribution of Ae. koreicus and evaluated the effectiveness of three trapping devices in Latin square experiments conducted in an urban site and a forested site. The following three different traps were compared: a CO2-baited Biogents (BG) Sentinel trap, a CO2-baited Centers for Disease Control and Prevention light trap (CDC trap), and a grass infusion-baited gravid trap.In northern Italy, Ae. koreicus was collected from late April to early November, with peak of abundance observed in August. Aedes koreicus was more abundant in 2015 than in 2014 because of higher temperatures during summer. Unlike Ae. albopictus, the abundance of Ae. koreicus was not related to the altitude of the sampling locations in the range 241-660 m above sea level. The BG Sentinel and gravid traps collected significantly more Ae. koreicus than the CDC trap in the urban site, whereas there was no significant difference between the three traps in the forested site. In the urban site, the BG Sentinel trap and the gravid trap were the most effective for collecting Ae. albopictus and Culex pipiens L., respectively. In the forested site, Cx. pipiens was primarily collected by the CDC trap. © The Authors 2017. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Trophic transfer of persistent organic pollutants through a pelagic food web: The case of Lake Como (Northern Italy).

PubMed

Mazzoni, Michela; Boggio, Emanuela; Manca, Marina; Piscia, Roberta; Quadroni, Silvia; Bellasi, Arianna; Bettinetti, Roberta

2018-05-30

Despite DDT and PCB having been banned for about 40 years, they are still detectable in the environment. In the present research we specifically investigated the trophic transfer of these organochlorine contaminants (OC) through a pelagic food web of a deep lake in Northern Italy (Lake Como) over time. Zooplankton and fish were sampled each season of a year and OC concentrations and the carbon and nitrogen isotopic ratios were measured. By using stable isotopes, the direct trophic relationship between pelagic zooplankton and zooplanktivorous fish was confirmed for Alosa agone only in summer. Based on this result, the biomagnification factor normalized on the trophic level (BMF TL ) for organic contaminants was calculated. BMF TL values were within the range 0.9-1.9 for DDT isomers and 1.6-4.9 for some PCB congeners (PCB 95, PCB 101, PCB 149, PCB 153, PCB 138 - present both in zooplankton and in fish and representing >60% of the PCB contamination), confirming the biomagnification of these compounds in one of the two zooplanktivorous fish species of the lake. Copyright © 2018. Published by Elsevier B.V.

Temperature Characterization of Different Urban Microhabitats of Aedes albopictus (Diptera Culicidae) in Central-Northern Italy.

PubMed

Vallorani, Roberto; Angelini, Paola; Bellini, Romeo; Carrieri, Marco; Crisci, Alfonso; Mascali Zeo, Silvia; Messeri, Gianni; Venturelli, Claudio

2015-08-01

Aedes albopictus (Skuse) is an invasive mosquito species that has spread to many countries in temperate regions bordering the Mediterranean basin, where it is becoming a major public health concern. A good knowledge of the thermal features of the most productive breeding sites for Ae. albopictus is crucial for a better estimation of the mosquitoes' life cycle and developmental rates. In this article, we address the problem of predicting air temperature in three microhabitats common in urban and suburban areas and the air and water temperature inside an ordinary catch basin, which is considered the most productive breeding site for Ae. albopictus in Italy. Temperature differences were statistically proven between the three microhabitats and between the catch basin external and internal temperature. The impacts on the developmental rates for each life stage of Ae. albopictus were tested through a parametric function of the temperature, and the aquatic stages resulted as being the most affected using the specific temperature inside a typical catch basin instead of a generic air temperature. The impact of snow cover on the catch basin internal temperature, and consequently on the mortality of diapausing eggs, was also evaluated. These data can be useful to improve epidemiological models for a better prediction of Ae. albopictus seasonal and population dynamics in central-northern Italian urban areas. © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Incidence of silicosis among ceramic workers in central Italy.

PubMed

Cavariani, F; Di Pietro, A; Miceli, M; Forastiere, F; Biggeri, A; Scavalli, P; Petti, A; Borgia, P

1995-01-01

The incidence of radiological silicosis was studied among 2480 male workers employed in the ceramics industry. The subjects entered the surveillance program during 1974-1987 and were followed through 1991 with annual chest radiographs. The cumulative risk of silicosis (1/1 or greater; p,q,r) reached 48% (95% confidence interval 41.5-54.9) after 30 years of employment. In a multivariate Cox's proportional hazards model, the effect of duration of exposure increased linearly up to the category of 25-29 years; an extremely high hazard risk of 14.6 was found among those with 30 years or more of exposure in comparison with those employed 10 years or less. Smoking habit also significantly contributed to the model, although its role in the biological process is unclear. In conclusion, exposure to silica dust has been associated with a high incidence of silicosis among ceramics workers. The risk estimates are consistent with the recent findings of silicosis incidence among South African gold miners.

First record of the Kuwana pine mealybug Crisicoccus pini (Kuwana) in Italy: a new threat to Italian pine forests?

PubMed

Boselli, Mauro; Pellizzari, Giuseppina

2016-02-19

The Asiatic Kuwana pine mealybug, Crisicoccus pini (Kuwana, 1902) (Hemiptera, Pseudococcidae), is reported in Italy for the first time. It was detected in September 2015 on maritime pine, Pinus pinaster, and stone pine, Pinus pinea, trees growing in the town of Cervia (Ravenna Province), Northern Italy. The mealybug has caused yellowing and decline of the pine trees. Pinus pinea is recorded here as a new host for C. pini.

Isoprene and its degradation products as strong ozone precursors in Insubria, Northern Italy

NASA Astrophysics Data System (ADS)

Duane, M.; Poma, B.; Rembges, D.; Astorga, C.; Larsen, B. R.

Frequent smog episodes occur during spring, summer, and autumn in Insubria, Northern Italy. On a test site in this area the atmospheric concentration of the photo-oxidants ozone and peroxyacetyl nitrate has been monitored over a year (2000) together with ozone precursors listed in the European Union Air Quality Directive 2002/3/EC, such as nitrous oxides (NO X) and volatile organic compounds (VOC) including hydrocarbons and carbonyls. The results of this study revealed a strong impact of biogenic isoprene on the air quality. In winter isoprene was detected at the ppt level and correlated with anthropogenic VOC. However, during the growing season isoprene exhibited a distinct diurnal variation with maximum concentrations late in the afternoon reaching up 70 ppbC attributed to strong emissions from the abundant vegetation of broad-leaf deciduous trees in this area. A new HPLC-MS method was developed for the determination of isoprene's primary atmospheric oxidation products methacrolein as its 2,4-dinitrophenylhydrazone and methyl vinyl ketone as an unusual double derivative with 2,4-dinitrophenylhydrazine. Methacrolein and methyl vinyl ketone followed the same diurnal and annual trends as isoprene. The average monthly concentration of isoprene and these products ranged from around 10 ppbC in June, July and September to 20 ppbC in August, which constitutes 15-30% of C 3-C 9 VOCs. The contribution from isoprene photo-oxidation to the ambient air formaldehyde concentrations was also found to be high during this period ranging from 30% to 60% in May, June, July and August. From the atmospheric VOC and NO X concentrations the local photochemical ozone formation was estimated by the incremental reactivity approach. The calculations showed that in summer isoprene's contribution to the local ozone formation was as high as 50-75%.

[Female migrants: Moroccan women in Northern Italy. A study in Venice].

PubMed

Schmidt Di Friedberg, O; Saint-blancat, C

1998-09-01

"Immigration of Moroccan women has only recently become in Italy the object of specific studies. Female migrants, although representing a minority when compared to their male counterparts, have drawn the attention of local society...because of their demands in the field of public health, family planning and education. This is the case of the Venetian Region." Differences between the immigrants' values and cultural background, and those of the receiving country, are considered. (EXCERPT)

Molecular detection and genetic characterization of circulating measles virus in northern Italy.

PubMed

Piccirilli, Giulia; Chiereghin, Angela; Pascucci, Maria Grazia; Frasca, Gabriella; Zuntini, Roberta; Ferrari, Simona; Gabrielli, Liliana; Landini, Maria Paola; Lazzarotto, Tiziana

2016-08-01

Laboratory diagnosis of measles virus (MV) infection and genetic characterization of circulating MV play an essential role in measles surveillance, allowing proper interventions to interrupt endemic transmission. We describe results obtained using serological and molecular methods to confirm MV infection among suspected cases reported in a large region in the north of Italy during 2010-2014 and the genotyping of the MV strains detected. Three hundred seventy-two samples (361 urine and 11 oral fluids) were tested for MV-RNA detection. In 281 cases, the serological results for MV-IgM detection were also available. A total of 276 cases were classified as confirmed measles and MV-RNA detection resulted positive for 239/276 cases. Nucleotide sequence analysis revealed sporadic cases of genotypes D9 and different circulations of endemic MV strains (D8, D4 and B3). This data suggests that there is still an unvaccinated part of the population maintaining the endemic circulation of MV in Italy. Copyright © 2016 Elsevier B.V. All rights reserved.

Incidence and seasonality of falls amongst old people receiving home help services in a municipality in northern Sweden.

PubMed

Vikman, Irene; Nordlund, Anders; Näslund, Annika; Nyberg, Lars

2011-04-01

Falls among old people is a well-documented phenomenon; however, falls among people living in the community and receiving home help services have been under-researched. The aim of this study was to investigate the incidence, including possible seasonal variation, circumstances and injuries related to falls among community living home help receivers, and to investigate whether fall incidence is associated with the type and amount of home help services received. Prospective cohort study. All 614 persons aged 65 and over who were living in a particular northern Swedish community and receiving municipality home help were included. Data on age, sex and home help service use were collected from home help service records, and falls were reported by staff on report forms specifically designed for the study. Results. A total number of 264 falls were recorded among 122 participants. The overall fall incidence was 626 per 1,000 PY, and incidence rate ratios were significantly correlated to the total amount of services used (p<0.001), as well as to the degree of help for I-ADL needs (p<0.001), P-ADL needs (p<0.001) and escort service (p=0.007). The proportion of falls reported as resulting in injury was 33%. The monthly fall incidence was significantly associated to daylight photoperiod, however it was not associated to temperature. Fall incidence among home help receivers aged 65 and over seems correlated to the amount of services they receive. This is probably explained by the fact that impairments connected to ADL limitations and home help needs also are connected to an increased risk of falls. This implies that fall prevention should be considered when planning home help care for old people with ADL limitations. Further research on the connection between daylight photoperiod and fall incidence in populations at different latitudes is needed.

Historical trends and high-resolution future climate projections in northern Tuscany (Italy)

NASA Astrophysics Data System (ADS)

D'Oria, Marco; Ferraresi, Massimo; Tanda, Maria Giovanna

2017-12-01

This paper analyzes the historical precipitation and temperature trends and the future climate projections with reference to the northern part of Tuscany (Italy). The trends are identified and quantified at monthly and annual scale at gauging stations with data collected for long periods (60-90 years). An ensemble of 13 Regional Climate Models (RCMs), based on two Representative Concentration Pathways (RCP4.5 and RCP8.5), was then used to assess local scale future precipitation and temperature projections and to represent the uncertainty in the results. The historical data highlight a general decrease of the annual rainfall at a mean rate of 22 mm per decade but, in many cases, the tendencies are not statistically significant. Conversely, the annual mean temperature exhibits an upward trend, statistically significant in the majority of cases, with a warming rate of about 0.1 °C per decade. With reference to the model projections and the annual precipitation, the results are not concordant; the deviations between models in the same period are higher than the future changes at medium- (2031-2040) and long-term (2051-2060) and highlight that the model uncertainty and variability is high. According to the climate model projections, the warming of the study area is unequivocal; a mean positive increment of 0.8 °C at medium-term and 1.1 °C at long-term is expected with respect to the reference period (2003-2012) and the scenario RCP4.5; the increments grow to 0.9 °C and 1.9 °C for the RCP8.5. Finally, in order to check the observed climate change signals, the climate model projections were compared with the trends based on the historical data. A satisfactory agreement is obtained with reference to the precipitation; a systematic underestimation of the trend values with respect to the models, at medium- and long-term, is observed for the temperature data.

The importance of a taste. A comparative study on wild food plant consumption in twenty-one local communities in Italy

PubMed Central

2007-01-01

A comparative food ethnobotanical study was carried out in twenty-one local communities in Italy, fourteen of which were located in Northern Italy, one in Central Italy, one in Sardinia, and four in Southern Italy. 549 informants were asked to name and describe food uses of wild botanicals they currently gather and consume. Data showed that gathering, processing and consuming wild food plants are still important activities in all the selected areas. A few botanicals were quoted and cited in multiple areas, demonstrating that there are ethnobotanical contact points among the various Italian regions (Asparagus acutifolius, Reichardia picroides, Cichorium intybus, Foeniculum vulgare, Sambucus nigra, Silene vulgaris, Taraxacum officinale, Urtica dioica, Sonchus and Valerianella spp.). One taxon (Borago officinalis) in particular was found to be among the most quoted taxa in both the Southern and the Northern Italian sites. However, when we took into account data regarding the fifteen most quoted taxa in each site and compared and statistically analysed these, we observed that there were a few differences in the gathering and consumption of wild food plants between Northern and Southern Italy. In the North, Rosaceae species prevailed, whereas in the South, taxa belonging to the Asteraceae, Brassicaceae, and Liliaceae s.l. families were most frequently cited. We proposed the hypothesis that these differences may be due to the likelihood that in Southern Italy the erosion of TK on wild vegetables is taking place more slowly, and also to the likelihood that Southern Italians' have a higher appreciation of wild vegetables that have a strong and bitter taste. A correspondence analysis confirmed that the differences in the frequencies of quotation of wild plants within the Northern and the Southern Italian sites could be ascribed only partially to ethnic/cultural issues. An additional factor could be recent socio-economic shifts, which may be having a continued effort on

A review of recent studies of goitre in Italy

PubMed Central

Costa, Aurelio; Mortara, Marcello

1960-01-01

The prevalence and distribution of both epidemic and endemic goitre in Italy since 1940 are reviewed and the main results of recent research into these two forms of the disease are specified. A number of epidemic outbreaks occurred between 1940 and 1948, all originally in areas of endemic goitre but sometimes spreading to localities from which endemic goitre had practically disappeared. Both persons long resident in these areas and new arrivals were affected, as were domestic animals. Acute goitres showed the same histological features as in the endemic form of the disease. Extrathyroid symptoms were sometimes noted. Studies of endemic goitre have failed to show any clear indication that lack of iodine is responsible for the condition. Epidemiologically, endemic goitre, which remains a predominantly rural disease, seems to be shifting gradually from northern to southern Italy. PMID:13849448

Modelling the Risk Posed by the Zebra Mussel Dreissena polymorpha: Italy as a Case Study

NASA Astrophysics Data System (ADS)

Bosso, Luciano; De Conno, Carmelina; Russo, Danilo

2017-08-01

We generated a risk map to forecast the potential effects of the spreading of zebra mussels Dreissena polymorpha across the Italian territory. We assessed the invader's potential impact on rivers, lakes, watersheds and dams at a fine-grained scale and detected those more at risk that should be targeted with appropriate monitoring. We developed a MaxEnt model and employed weighted overlay analyses to detect the species' potential distribution and generate risk maps for Italy. D. polymorpha has a greater probability of occurring at low to medium altitudes in areas characterised by fluviatile deposits of major streams. Northern and central Italy appear more at risk. Some hydroelectric power dams are at high risk, while most dams for irrigation, drinkable water reservoirs and other dam types are at medium to low risk. The lakes and rivers reaches (representing likely expansion pathways) at medium-high or high risk mostly occur in northern and central Italy. We highlight the importance of modelling potential invasions on a country scale to achieve the sufficient resolution needed to develop appropriate monitoring plans and prevent the invader's harmful effects. Further high-resolution risk maps are needed for other regions partly or not yet colonised by the zebra mussel.

The necropolis of Bolgare (Lombardy, Italy): Anthropological and paleopathological features of a Lombard population.

PubMed

Sguazza, E; Mazzucchi, A; Fortunati, M; Cattaneo, C

2015-04-01

The mediaeval necropolis of Bolgare - St. Chierico is an important site in northern Italy, located in the Bergamo Province (about 40 km East of Milan). In order to reconstruct aspects of the demographic and health status of this Lombard population, macroscopic (morphological, metric and radiographic) and microscopic analyses were performed on over 400 skeletons for the assessments of sex (cranial and pelvic morphology, metrics), age (subadults: dental and bone development; adults: mainly pubic symphysis, auricular surface of the ilium, 4th rib) and stature, for the determination of ancestry and the identification of pathologies. Results proved the sample to be heterogeneous with males, females, adults and subadults. The sample seemed to be composed of several groups, including individuals with northern or eastern (Uralic) European features and, on the other hand, individuals with central European or Mediterranean characteristics. The first may be indicative of migrations of Lombards (suggested by tall stature estimates); the second could be considered autochthonous, bearing features more typical of northern Italian populations. Among palaeopathological finds, the study showed the presence of tuberculosis, gout, DISH and degenerative pathologies particularly on the pelvis and spinal column. The population of Bolgare constitutes one of the main sources of anthropological data on Lombards in Italy. Copyright © 2015 Elsevier GmbH. All rights reserved.

An integrated approach to coastal erosion problems in northern Tuscany (Italy): Littoral morphological evolution and cell distribution

NASA Astrophysics Data System (ADS)

Anfuso, G.; Pranzini, E.; Vitale, G.

2011-06-01

Occupation of the coast has significantly increased in recent decades, mostly due to a greater demand for recreation and tourism. Today, erosion threatens many human-made structures and activities, requiring an integrated approach for the understanding of coastal dynamics and identification of alternatives to associated problems. This study investigates a 64 km-long coastal physiographic unit in the northern microtidal littoral of Tuscany (Italy). Vertical aerial photographs and direct field surveys were used to retrieve changes in shoreline position over 1938-1997 and 1997-2005 time intervals. Significant beach accretion was observed during the first period updrift of Carrara (84 m) and Viareggio (280 m) harbours and at Marina di Pietrasanta (100 m), whereas severe erosion occurred downcoast of Carrara harbour (- 130 m, at Marina dei Ronchi) and on the northern side of Arno river mouth (- 400 m). Similar trends were observed between 1997 and 2005; beach slope between the 1997 shoreline position and the closure depth correlated well with the distribution of erosion/accretion patterns from the 1938-1997 period (slopes were lower in eroded areas than at sites under accretion). Longshore distribution of erosion/accretion patterns was controlled by coastal compartmentalisation. Three of the main littoral cells were mostly formed by natural limits (i.e., Punta Bianca promontory, Marina di Pietrasanta, the Arno river mouth and the port of Livorno). Several sub-cells were created within these cells due to the introduction of human-made structures (such as Carrara and Viareggio harbours), which formed artificial fixed limits that allowed the transport of sediments (exclusively fines) in one direction only. Results will help improve the understanding of coastal processes and manage littoral sediment transport in a sustainable manner. This will reduce the need for structural interventions, such as breakwaters and groynes, which in the past decades prevented coastal retreat

Environmental changes in the central Po Plain (northern Italy) due to fluvial modifications and anthropogenic activities

NASA Astrophysics Data System (ADS)

Marchetti, Mauro

2002-05-01

The fluvial environment of the central Po Plain, the largest plain in Italy, is discussed in this paper. Bounded by the mountain chains of the Alps and the Apennines, this plain is a link between the Mediterranean environment and the cultural and continental influences of both western and eastern Europe. In the past decades, economic development has been responsible for many changes in the fluvial environment of the area. This paper discusses the changes in fluvial dynamics that started from Late Pleistocene and Early Holocene due to distinct climatic changes. The discussion is based on geomorphological, pedological, and archaeological evidences and radiocarbon dating. In the northern foothills, Late Pleistocene palaeochannels indicate several cases of underfit streams among the northern tributaries of the River Po. On the other hand, on the southern side of the Po Plain, no geomorphological evidence of similar discharge reduction has been found. Here, stratigraphic sections, together with archaeological remains buried under the fluvial deposits, show a reduction in the size of fluvial sediments after the 10th millennium BC. During the Holocene, fluvial sedimentation became finer, and was characterised by minor fluctuations in the rate of deposition, probably related to short and less intense climatic fluctuations. Given the high rate of population growth and the development of human activities since the Neolithic Age, human influence on fluvial dynamics, especially since the Roman Age, prevailed over other factors (i.e., climate, tectonics, vegetation, etc.). During the Holocene, the most important changes in the Po Plain were not modifications in water discharge but in sediment. From the 1st to 3rd Century AD, land grants to war veterans caused almost complete deforestation, generalised soil erosion, and maximum progradation of the River Po delta. At present, land abandonment in the mountainous region has led to reafforestation. Artificial channel control in the

Petrography and chemistry of tungsten-rich oxycalciobetafite in hydrothermal veins of the Adamello contact aureole, northern Italy

NASA Astrophysics Data System (ADS)

Lumpkin, Gregory R.; Gieré, Reto; Williams, C. Terry; McGlinn, Peter J.; Payne, Timothy E.

2017-09-01

Tungsten-rich oxycalciobetafite occurs in complex Ti-rich hydrothermal veins emplaced within dolomite marble in the contact aureole of the Adamello batholith, northern Italy, where it occurs as overgrowths on zirconolite. The betafite is weakly zoned and contains 29-34 wt% UO2. In terms of end-members, the betafite contains approximately 50 mol% CaUTi2O7 and is one of the closest known natural compositions to the pyrochlore phase proposed for use in titanate nuclear waste forms. Amorphization and volume expansion of the betafite caused cracks to form in the enclosing silicate mineral grains. Backscattered electron images reveal that betafite was subsequently altered along crystal rims, particularly near the cracks. Electron probe microanalyses reveal little difference in composition between altered and unaltered areas, except for lower totals, suggesting that alteration is primarily due to hydration. Zirconolite contains up to 18 wt% ThO2 and 24 wt% UO2, and exhibits strong compositional zoning, but no internal cracking due to differential (and anisotropic) volume expansion and no visible alteration. The available evidence demonstrates that both oxycalciobetafite and zirconolite retained actinides for approximately 40 million years after the final stage of vein formation. During this time, oxycalciobetafite and zirconolite accumulated a total alpha-decay dose of 3.0-3.6 × 1016 and 0.2-2.0 × 1016 α/mg, respectively.

Analysis of the precipitation and streamflow extremes in Northern Italy using high resolution reanalysis dataset Express-Hydro

NASA Astrophysics Data System (ADS)

Silvestro, Francesco; Parodi, Antonio; Campo, Lorenzo

2017-04-01

The characterization of the hydrometeorological extremes, both in terms of rainfall and streamflow, in a given region plays a key role in the environmental monitoring provided by the flood alert services. In last years meteorological simulations (both near real-time and historical reanalysis) were available at increasing spatial and temporal resolutions, making possible long-period hydrological reanalysis in which the meteo dataset is used as input in distributed hydrological models. In this work, a very high resolution meteorological reanalysis dataset, namely Express-Hydro (CIMA, ISAC-CNR, GAUSS Special Project PR45DE), was employed as input in the hydrological model Continuum in order to produce long time series of streamflows in the Liguria territory, located in the Northern part of Italy. The original dataset covers the whole Europe territory in the 1979-2008 period, at 4 km of spatial resolution and 3 hours of time resolution. Analyses in terms of comparison between the rainfall estimated by the dataset and the observations (available from the local raingauges network) were carried out, and a bias correction was also performed in order to better match the observed climatology. An extreme analysis was eventually carried on the streamflows time series obtained by the simulations, by comparing them with the results of the same hydrological model fed with the observed time series of rainfall. The results of the analysis are shown and discussed.

Forest fires in Italy: An econometric analysis of major driving factors

NASA Astrophysics Data System (ADS)

Michetti, Melania; Pinar, Mehmet

2013-04-01

Despite the relevant fire risk to which Italy is subject from north to south, very few analysis focus on this area. This article investigates the causes of forest fires frequency and intensity in Italy during the first decade of the XXI century. The dynamical aspects of fire danger are explored through the use of panel data techniques which fully capture the impacts on forest fires of changes in both socio-economic and climatic conditions. Italy is treated as a unique region in a first model specification, while it is then split into 3 geographical areas (north, centre, and south) to capture locally specific aspects. Two different dependent variables are alternatively employed and a number of ad hoc tests are performed to corroborate the robustness of our estimates. Results highlight the importance of considering the fire situation separately for the northern, central, and southern parts of Italy. While the presence of railway networks positively affects fire risk, the impact of livestock depends on its specific composition. Favourable effects in fire reduction are represented by the increase in education levels (north and centre) and touristic flows (north and south), and by the containment of illegal activities (south). Weather patterns appear to be important determinants all over the Italian peninsula.

Point-of-care screening, prevalence, and risk factors for hepatitis B infection among 3,728 mainly undocumented migrants from non-EU countries in northern Italy.

PubMed

El-Hamad, Issa; Pezzoli, Maria Chiara; Chiari, Erika; Scarcella, Carmelo; Vassallo, Francesco; Puoti, Massimo; Ciccaglione, Anna; Ciccozzi, Massimo; Scalzini, Alfredo; Castelli, Francesco

2015-01-01

Screening migrants from areas where hepatitis B virus (HBV) infection is endemic is important to implement preventive measures in Europe. The aim of our study was to assess (1) the feasibility of point-of-care screening in a primary care clinic and (2) hepatitis B surface antigen (HBsAg) prevalence, associated risk factors, and its clinical and epidemiological implications in undocumented migrants in Brescia, northern Italy. A longitudinal prospective study was conducted from January 2006 to April 2010 to assess HBsAg reactivity and associated risk factors among consenting undocumented migrants who accessed the Service of International Medicine of Brescia's Local Health Authority. Genotyping assay was also performed in HBV DNA-positive patients. Screening was accepted by 3,728/4,078 (91.4%) subjects consecutively observed during the study period, 224 (6%) of whom were found to be HBsAg-positive. HBsAg reactivity was independently associated with the prevalence of HBsAg carriers in the geographical area of provenance (p < 0.001). On the contrary, current or past sexual risk behaviors (despite being common in our sample) were not associated with HBV infection. Half of the HBsAg patients (111/224) had either hepatitis B e-antigen (HBeAg)-positive or -negative chronic HBV infection with a possible indication for treatment. HBV genotypes were identified in 45 of 167 HBV-infected patients as follows: genotype D, 27 subjects; genotype A, 8; genotype B, 5; and genotype C, 5. The geographical distribution of genotypes reflected the geographic provenance. Our results suggest that point-of-care screening is feasible in undocumented migrants and should be targeted according to provenance. Case detection of HBV infection among migrants could potentially reduce HBV incidence in migrants' contacts and in the general population by prompting vaccination of susceptible individuals and care of eligible infected patients. © 2014 International Society of Travel Medicine.

Mercury Enrichment in Sediments of the Coastal Area of Northern Latium, Italy.

PubMed

Scanu, Sergio; Piazzolla, Daniele; Frattarelli, Francesco Manfredi; Mancini, Emanuele; Tiralongo, Francesco; Brundo, Maria Violetta; Tibullo, Daniele; Pecoraro, Roberta; Copat, Chiara; Ferrante, Margherita; Marcelli, Marco

2016-05-01

The purpose of this study was to evaluate the extent of the Hg geochemical anomaly arising in the Amiata and Tolfa complex to the coastal area of northern Latium and to examine the possible influence on this area by the Mignone River, and by the small coastal basins, which are characterized by both previous mining activities and decades of past industrial impact. The results confirm the extension of the anomaly of concentrations of Hg in the coastal area of northern Latium, with the northern sector influenced by the contributions of the Fiora and Mignone Rivers and the southern sector influenced by the contributions of minor basins. The results show high values of the Adverse Effect Index throughout the considered area and highlight the need for further investigation in order to assess the impact of human activities on the present and past values of Hg in marine sediments.

History and updating on the spread of Aedes albopictus in Italy.

PubMed

Romi, R

1995-12-01

The present distribution in Italy of Aedes albopictus, the Asian mosquito recently introduced, is described. Until now this mosquito species has been established in 8 regions of our country: Liguria, Veneto, Lazio, Lombardia, Emilia-Romagna, Toscana, Piemonte and recently Sardegna. The established populations have been able to overcome the winter season. These populations, certainly imported from temperate areas, have reconfirmed the great adaptation of the species, reaching the high latitude of 46 degrees North of the Padova area in Northern Italy. The origin of the infestation in Veneto region was shown to be strictly related to the importation of used tires and demonstrated at least for one load of tires from USA. The internal trading of tires from Veneto is the source of infestation of the other Italian regions, with the exception of Liguria and Lazio. Since the introduction and the establishment of Ae. albopictus in Italy represent a new problem of public health, a centre for the surveillance and control of this species has been set up at the Department of Parasitology, Istituto Superiore di Sanità, Roma.

Sperm quality and environment: A retrospective, cohort study in a Northern province of Italy

DOE Office of Scientific and Technical Information (OSTI.GOV)

Santi, Daniele, E-mail: santi.daniele@gmail.com; Department of Medicine, Endocrinology, Metabolism and Geriatrics; Vezzani, Silvia

Background: Several studies proposed a relationship between environmental factors and semen quality, as well as the negative effect of air pollution on spermatogenesis and gonadal function. No specific studies evaluated the environmental influence on semen quality in a specific geographical area. Aim: to evaluate the environmental influence on male sperm parameters in a Northern Italian population referred for semen analysis in the National Health System. The objective of the study is the assessment of the relationship of both air pollution and environmental parameters with quality-related sperm variables, during the coldest months of the year when air is usually most polluted,more » due to low ventilation and poor rainfall. Study design: A retrospective, observational, cohort study was carried out in the province of Modena, located in the Emilia-Romagna region of Northern Italy. Methods: Semen analyses (n=406), environmental temperature, air humidity and air particulate matter (PM) measurements from the 1st of November 2014 to the 19th of February 2015 were acquired to the first database. Since spermatogenesis lasts over two months, a second, wider database was arranged, evaluating environmental exposure in the 3 months before semen collection (from August 1st 2014). All data included in the database were registered by geo-coding the residential address of the patients and the site of registration of environmental factors. The geo-codification of parameters was performed using Fusion Tables of Google available at (https://www.google.com/fusiontables/data? dsrcid=implicit), considering the exact time of measurement. Results: Average air temperature was inversely related to sperm concentration and to total sperm number (p<0.001). Semen volume was inversely related only to the minimum (p<0.001) and not to maximum recorded temperature (p=0.110). Air humidity was not related to sperm quantity and quality. PM{sub 2.5} was directly related to total sperm number (p<0

Sperm quality and environment: A retrospective, cohort study in a Northern province of Italy.

PubMed

Santi, Daniele; Vezzani, Silvia; Granata, Antonio Rm; Roli, Laura; De Santis, Maria Cristina; Ongaro, Chiara; Donati, Federica; Baraldi, Enrica; Trenti, Tommaso; Setti, Monica; Simoni, Manuela

2016-10-01

Several studies proposed a relationship between environmental factors and semen quality, as well as the negative effect of air pollution on spermatogenesis and gonadal function. No specific studies evaluated the environmental influence on semen quality in a specific geographical area. to evaluate the environmental influence on male sperm parameters in a Northern Italian population referred for semen analysis in the National Health System. The objective of the study is the assessment of the relationship of both air pollution and environmental parameters with quality-related sperm variables, during the coldest months of the year when air is usually most polluted, due to low ventilation and poor rainfall. A retrospective, observational, cohort study was carried out in the province of Modena, located in the Emilia-Romagna region of Northern Italy. Semen analyses (n=406), environmental temperature, air humidity and air particulate matter (PM) measurements from the 1st of November 2014 to the 19th of February 2015 were acquired to the first database. Since spermatogenesis lasts over two months, a second, wider database was arranged, evaluating environmental exposure in the 3 months before semen collection (from August 1st 2014). All data included in the database were registered by geo-coding the residential address of the patients and the site of registration of environmental factors. The geo-codification of parameters was performed using Fusion Tables of Google available at https://www.google.com/fusiontables/data? dsrcid=implicit, considering the exact time of measurement. Average air temperature was inversely related to sperm concentration and to total sperm number (p<0.001). Semen volume was inversely related only to the minimum (p<0.001) and not to maximum recorded temperature (p=0.110). Air humidity was not related to sperm quantity and quality. PM2.5 was directly related to total sperm number (p<0.001). PM10 was directly related to both semen volume (0<0.001), and

Sinuosity change of the Po River near Cremona (Northern Italy) - a result of neotectonic activity?

NASA Astrophysics Data System (ADS)

Petrovszki, Judit; Timár, Gábor

2010-05-01

In the map sheets of the Second Military Survey of the Habsburg Empire, Lombardia, Parma, Modena and Venice also can be seen (Timár et al., 2006). This area was surveyed between 1818 and 1829. In these map sheets, we can also follow the river Po from Vaccarizza to the delta. This river reach is about 350 km long. This river reach was digitized and sinuosity values were calculated with different window sizes, and displayed in a spectrum-like diagram (sinuosity spectra; after van Balen et al., 2008). At Cremona, a significante sinuosity change were identified. The sinuosity increasing, and we have high sinuosity values. In the summarizing geological map of Italy (Compagnoni and Calluzzo, 2004), at this place, a tectonic line was identified. So probably this fault line invokes the sinuosity change on the river. The vertical movements indicated on the maps are just the opposite like they would be according to the flume experiments of Ouchi (1985). In the case of the Po River at Cremona, the decrease of the channel slope results higher sinuosity. The reason is that the rate of the slope and water discharge is higher than it is required by the self-organized meandering and the river parameters fell to the range of the unorganized meandering (cf. Timár, 2003). Another possible explanation could be that the northern tributary, the Adda River has significant sediment load that lowers the sinuosity of the trunk river at the confluence. Compagnoni, B., Galluzzo, F. (eds., 2004): Geological Map of Italy. Agenzia per la Protezione dell'Ambiente per I Servizi Tecnici - Dipartimento Difesa del Suolo, Servizio Geologico d'Italia, Rome-Florence-Genoa. Map, scale=1:1250000, especially printed for the 32nd International Geological Congress. Ouchi, S. (1985): Response of alluvial rivers to slow active tectonic movement. Geol. Soc. Am. Bull. 96: 504-515. Timár, G. (2003): Controls on channel sinuosity changes: a case study of the Tisza River, the Great Hungarian Plain. Quaternary

Italian cancer figures--Report 2015: The burden of rare cancers in Italy.

PubMed

Busco, Susanna; Buzzoni, Carlotta; Mallone, Sandra; Trama, Annalisa; Castaing, Marine; Bella, Francesca; Amodio, Rosalba; Bizzoco, Sabrina; Cassetti, Tiziana; Cirilli, Claudia; Cusimano, Rosanna; De Angelis, Roberta; Fusco, Mario; Gatta, Gemma; Gennaro, Valerio; Giacomin, Adriano; Giorgi Rossi, Paolo; Mangone, Lucia; Mannino, Salvatore; Rossi, Silvia; Pierannunzio, Daniela; Tavilla, Andrea; Tognazzo, Sandro; Tumino, Rosario; Vicentini, Massimo; Vitale, Maria Francesca; Crocetti, Emanuele; Dal Maso, Luigino

2016-01-01

This collaborative study, based on data collected by the network of Italian Cancer Registries (AIRTUM), describes the burden of rare cancers in Italy. Estimated number of new rare cancer cases yearly diagnosed (incidence), proportion of patients alive after diagnosis (survival), and estimated number of people still alive after a new cancer diagnosis (prevalence) are provided for about 200 different cancer entities. Data herein presented were provided by AIRTUM population- based cancer registries (CRs), covering nowadays 52% of the Italian population. This monograph uses the AIRTUM database (January 2015), which includes all malignant cancer cases diagnosed between 1976 and 2010. All cases are coded according to the International Classification of Diseases for Oncology (ICD-O-3). Data underwent standard quality checks (described in the AIRTUM data management protocol) and were checked against rare-cancer specific quality indicators proposed and published by RARECARE and HAEMACARE (www.rarecarenet.eu; www.haemacare.eu). The definition and list of rare cancers proposed by the RARECAREnet "Information Network on Rare Cancers" project were adopted: rare cancers are entities (defined as a combination of topographical and morphological codes of the ICD-O-3) having an incidence rate of less than 6 per 100,000 per year in the European population. This monograph presents 198 rare cancers grouped in 14 major groups. Crude incidence rates were estimated as the number of all new cancers occurring in 2000-2010 divided by the overall population at risk, for males and females (also for gender-specific tumours).The proportion of rare cancers out of the total cancers (rare and common) by site was also calculated. Incidence rates by sex and age are reported. The expected number of new cases in 2015 in Italy was estimated assuming the incidence in Italy to be the same as in the AIRTUM area. One- and 5-year relative survival estimates of cases aged 0-99 years diagnosed between 2000 and

Egg-related Salmonella enteritidis, Italy, 1991

PubMed Central

Binkin, N.; Scuderi, G.; Novaco, F.; Giovanardi, G. L.; Paganelli, G.; Ferrari, G.; Cappelli, O.; Ravaglia, L.; Zilioli, F.; Amadei, V.; Magliani, W.; Viani, I.; Riccò, D.; Borrini, B.; Magri, M.; Alessandrini, A.; Bursi, G.; Barigazzi, G.; Fantasia, M.; Filetici, E.; Salmaso, S.

1993-01-01

In recent years, Salmonella enteritidis has become an increasingly important public health problem in Italy. In some parts of the country, the fraction of total human salmonella isolates accounted for by S. enteritidis has risen from 3-4% in the mid-1980s to more than 30% in 1990. Between 1990 and 1991, the number of reported S. enteritidis outbreaks increased more than sixfold. The 33 outbreaks reported in 1991 occurred in seven contiguous regions in northern and central Italy and were clustered in time between June and October; in the majority, products containing raw or undercooked shell eggs were implicated. Five of the egg-related outbreaks that occurred within a 30 kilometre radius over a 7-week period were investigated in detail. A phage type 1 strain containing a 38·9 MDa plasmid appeared responsible for three of the outbreaks, while in the remaining two a phage type 4 strain, also with a 38·9 MDa plasmid was isolated. Efforts are being made to enhance epidemiological surveillance and laboratory evaluation, and the use of pasteurized eggs has been recommended for high-risk populations. PMID:8472765

Simulation supported scenario analysis for water resources planning: a case study in northern italy

NASA Astrophysics Data System (ADS)

Facchi, A.; Gandolfi, C.; Ortuani, B.; Maggi, D.

2003-04-01

The work presents the results of a comprehensive modelling study of surface and groundwater systems, including the interaction between irrigation and groundwater resources, for the Muzza-Bassa Lodigiana irrigation district, placed in the southern part of the densely-settled Lombardia plain (northern Italy). The area, of approximately 700 km2, has been selected as: a) it is representative of agricultural and irrigation practices in a wide portion of the plain of Lombardia; b) it has well defined hydrogeological borders, represented by the Adda, Po, and Lambro rivers (respectively East, South and West) and by the Muzza canal (North). The objective of the study is to assess the impact of land use and irrigation water availability on the distribution of crop water consumption in space and time, as well as on the groundwater resources in this wide portion of the Lombardia plain. To achieve this goal, a number of realistic management scenarios, currently under discussion with the regional water authority, have been taken into account. A standard 'base case' has been defined to allow comparative analysis of the results of different scenarios. To carry out the research, an integrated, distributed, catchment-scale simulation package, already developed and applied to the study area, has been used. The simulation system is based on the integration of two hydrological models - a conceptual vadose zone model and the groundwater model MODFLOW. An interface performs the explicit coupling in space and time between the two models. A GIS manages all the information relevant to the study area, as well as all the input, the spatially distributed parameters and the output of the system. The simulation package has been verified for the years 1999-2000 using land use derived from remote-sensed images, reported water availability for irrigation, observed water stage in rivers as well as groundwater level in the alluvial aquifer system.

A coupled distributed hydrological-stability analysis on a terraced slope of Valtellina (northern Italy)

NASA Astrophysics Data System (ADS)

Camera, C.; Apuani, T.; Masetti, M.

2013-02-01

The aim of this work was to understand and reproduce the hydrological dynamics of a slope, which was terraced using dry-stone retaining walls and its response to these processes in terms of stability at the slope scale. The slope studied is located in Valtellina (northern Italy), near the village of Tresenda, and in the last 30 yr has experienced several soil slip/debris flow events. In 1983 alone, such events caused the death of 18 people. Direct observation of the events of 1983 enabled the principal triggering cause of these events to be recognized in the formation of an overpressure at the base of a dry-stone wall, which caused its failure. To perform the analyses it is necessary to include the presence of dry-stone walls, considering the importance they have in influencing hydrological and geotechnical processes at the slope scale. This requires a very high resolution DEM (1 m × 1 m because the walls are from 0.60 m to 1.0 m wide) that has been appositely derived. A hydrogeological raster-based model, which takes into account both the unsaturated and saturated flux components, was applied. This was able to identify preferential infiltration zones and was rather precise in the prediction of maximum groundwater levels, providing valid input for the distributed stability analysis. Results of the hydrogeological model were used for the successive stability analysis. Sections of terrace were identified from the downslope base of a retaining wall to the top of the next downslope retaining wall. Within each section a global method of equilibrium was applied to determine its safety factor. The stability model showed a general tendency to overestimate the amount of unstable areas. An investigation of the causes of this unexpected behavior was, therefore, also performed in order to progressively improve the reliability of the model.

Interdisciplinary approach for disaster risk reduction in Valtellina Valley, northern Italy

NASA Astrophysics Data System (ADS)

Garcia, Carolina; Blahut, Jan; Luna, Byron Quan; Poretti, Ilaria; Camera, Corrado; de Amicis, Mattia; Sterlacchini, Simone

2010-05-01

Inside the framework of the European research network Mountain Risks, an interdisciplinary research group has been working in the Consortium of Mountain Municipalities of Valtellina di Tirano (northern Italy). This area has been continuously affected by several mountain hazards such as landslides, debris flows and floods that directly affect the population, and in some cases caused several deaths and million euros of losses. An aim of the interdisciplinary work in this study area, is to integrate different scientific products of the research group, in the areas of risk assessment, management and governance, in order to generate, among others, risk reduction tools addressed to general public and stakeholders. Two types of phenomena have been particularly investigated: debris flows and floods. The scientific products range from modeling to mapping of hazard and risk, emergency planning based on real time decision support systems, surveying for the evaluation of risk perception and preparedness, among others. Outputs from medium scale hazard and risk modeling could be used for decision makers and spatial planners as well as civil protection authorities to have a general overview of the area and indentify hot spots for further detailed analysis. Subsequently, local scale analysis is necessary to define possible events and risk scenarios for emergency planning. As for the modeling of past events and new scenarios of debris flows, physical outputs were used as inputs into physical vulnerability assessment and quantitative risk analysis within dynamic runout models. On a pilot zone, the physical damage was quantified for each affected structure within the context of physical vulnerability and different empirical vulnerability curves were obtained. Prospective economic direct losses were estimated. For floods hazard assessment, different approaches and models are being tested, in order to produce flood maps for various return periods, and related to registered rainfalls

Diagnosis and incidence risk of clinical canine monocytic ehrlichiosis under field conditions in Southern Europe.

PubMed

René-Martellet, Magalie; Lebert, Isabelle; Chêne, Jeanne; Massot, Raphaël; Leon, Marta; Leal, Ana; Badavelli, Stefania; Chalvet-Monfray, Karine; Ducrot, Christian; Abrial, David; Chabanne, Luc; Halos, Lénaïg

2015-01-06

Canine Monocytic Ehrlichiosis (CME), due to the bacterium Ehrlichia canis and transmitted by the brown dog tick Rhipicephalus sanguineus, is a major tick-borne disease in southern Europe. In this area, infections with other vector-borne pathogens (VBP) are also described and result in similar clinical expression. The aim of the present study was to evaluate the incidence risk of clinical CME in those endemic areas and to assess the potential involvement of other VBP in the occurrence of clinical and/or biological signs evocative of the disease. The study was conducted from April to November 2011 in veterinary clinics across Italy, Spain and Portugal. Sick animals were included when fitting at least three clinical and/or biological criteria compatible with ehrlichiosis. Serological tests (SNAP®4Dx, SNAP®Leish tests, Idexx, USA) and diagnostic PCR for E. canis, Anaplasma platys, Anaplasma phagocytophilum, Babesia spp, Hepatozoon canis and Leishmania infantum detection were performed to identify the etiological agents. Ehrlichiosis was considered when three clinical and/or biological suggestive signs were associated with at least one positive paraclinical test (serology or PCR). The annual incidence risk was calculated and data were geo-referenced for map construction. The probabilities of CME and other vector-borne diseases when facing clinical and/or biological signs suggestive of CME were then evaluated. A total of 366 dogs from 78 veterinary clinics were enrolled in the survey. Among them, 99 (27%) were confirmed CME cases, which allowed an estimation of the average annual incidence risk of CME amongst the investigated dog population to be 0.08%. Maps showed an increasing gradient of CME incidence risk from northern towards southern areas, in particular in Italy. It also suggested the existence of hot-spots of infections by VBP in Portugal. In addition, the detection of other VBP in the samples was common and the study demonstrated that a dog with clinical signs

A high incidence of parthenogenesis in agricultural pests.

PubMed

Hoffmann, Ary A; Reynolds, K Tracy; Nash, Michael A; Weeks, Andrew R

2008-11-07

Parthenogenetic species are assumed to represent evolutionary dead ends, yet parthenogenesis is common in some groups of invertebrates particularly in those found in relatively constant environments. This suggests that parthenogenetic reproduction might be common in pest invertebrates from uniform agricultural environments. Based on the evaluations of two databases from North America and Italy, we found that parthenogenetic species comprised 45 per cent (North America) or 48 per cent (Italy) of pest species derived from genera where parthenogenesis occurred, compared with an overall incidence of 10 per cent or 16 per cent in these genera. In establishing these patterns, we included only genera containing at least some member species that reproduced by parthenogenesis. The high incidence of parthenogenesis in pest species is spread across different families and several insect orders. Parthenogenetic reproduction may be favoured in agricultural environments when particular clones have a high fitness across multiple generations. Increasing the complexity and variability of agricultural environments represents one way of potentially controlling parthenogenetic pest species.

A high incidence of parthenogenesis in agricultural pests

PubMed Central

Hoffmann, Ary A; Tracy Reynolds, K; Nash, Michael A; Weeks, Andrew R

2008-01-01

Parthenogenetic species are assumed to represent evolutionary dead ends, yet parthenogenesis is common in some groups of invertebrates particularly in those found in relatively constant environments. This suggests that parthenogenetic reproduction might be common in pest invertebrates from uniform agricultural environments. Based on the evaluations of two databases from North America and Italy, we found that parthenogenetic species comprised 45 per cent (North America) or 48 per cent (Italy) of pest species derived from genera where parthenogenesis occurred, compared with an overall incidence of 10 per cent or 16 per cent in these genera. In establishing these patterns, we included only genera containing at least some member species that reproduced by parthenogenesis. The high incidence of parthenogenesis in pest species is spread across different families and several insect orders. Parthenogenetic reproduction may be favoured in agricultural environments when particular clones have a high fitness across multiple generations. Increasing the complexity and variability of agricultural environments represents one way of potentially controlling parthenogenetic pest species. PMID:18647717

Epidemiological study of myasthenia gravis in the province of Reggio Emilia, Italy.

PubMed

Guidetti, D; Sabadini, R; Bondavalli, M; Cavalletti, S; Lodesani, M; Mantegazza, R; Cosi, V; Solime, F

1998-06-01

We carried out a retrospective incidence, prevalence and mortality survey of myasthenia gravis in the province of Reggio Emilia in Northern Italy. Based on 49 patients, the mean incidence per year for the period 1980 through 1994 was 7.8 per 1,000,000. On 31 December 1994 the prevalence rate was 117.5 per 1,000,000 for all patients, either active or recovered (50 cases in a population of 427,493) and 103.4 per 1,000,000 for the active disease. In the 15-year period 1980-1994 the average mortality rate was 1.0 per 1,000,000 per year. The average age at onset was 44.6 +/- 21.0, and the average age at the time of prevalence determination was 51.1 +/- 19.6 for the active disease. At the time of diagnosis, 21 patients (36.8%) were classed in group I according to Osserman's criteria, 31 in group II (54.4%), (19 in group II-A and 12 in group II-B), and the other 5 (8.8%) in group III. Of all the prevalence cases, 6 (12%) were in remission without therapy and 6 with therapy, while most of the others 16 (32%) were classed in group I, 15 (30%) in group II, and 1 (2%) in group III. Thymectomy was performed in 20 patients (35.1%), 12 (21%) had thymoma (malignant in 4 cases), 6 had thymic hyperplasia while in two patients thymic histology was normal. The relation the grade of Osserman's scale at the time of incidence and the presence of thymoma were significant. Higher grades of Osserman's scale were associated were malignant thymoma. Furthermore the relationship between thymectomy and the grade of Osserman's scale at the date of prevalence was significant for the presence of lower grades of Osserman's scale in the patients submitted to thymectomy.

Lung cancer risk in the electroplating industry in Lombardy, Italy, using the Italian occupational cancer monitoring (OCCAM) information system.

PubMed

Panizza, Celestino; Bai, Edoardo; Oddone, Enrico; Scaburri, Alessandra; Massari, Stefania; Modonesi, Carlo; Contiero, Paolo; Marinaccio, Alessandro; Crosignani, Paolo

2012-01-01

Occupational Cancer Monitoring (OCCAM) is an Italian organization that monitors occupational cancers, by area and industrial sector, by retrieving cases and employment history from official databases. OCCAM previously estimated a relative risk (RR) of lung cancer of about 1.32 among "metal treatment" workers in Lombardy, northern Italy, potentially exposed to chrome and nickel. In the present study, lung cancer risk was estimated among electroplating workers only. Lombardy electroplating companies were identified from descriptions in Social Security files. Lung cancer risk was evaluated from 2001 to 2008 incident cases identified from hospital discharge records. The RR for lung cancer among electroplating workers was 2.03 (90% CI 1.33-3.10, 18 cases) for men; 3.00 (90% CI 1.38-9.03, 4 cases) for women. Electroplaters had higher risks than "metal treatment" workers. Although the risks were due to past exposure, case histories and recent acute effects indicate a present carcinogenic hazard in some Lombardy electroplating factories. Copyright © 2011 Wiley Periodicals, Inc.

Evidence for bovine besnoitiosis being endemic in Italy--first in vitro isolation of Besnoitia besnoiti from cattle born in Italy.

PubMed

Gentile, A; Militerno, G; Schares, G; Nanni, A; Testoni, S; Bassi, P; Gollnick, N S

2012-03-23

Until 2009, bovine besnoitiosis had never been considered endemic in Italy and the only report on the disease in this country referred to animals imported from France shortly before. However, recently, an autochthonous outbreak of bovine besnoitiosis was reported in four herds located at the intersection of the borders between Emilia-Romagna, Toscana and Marche (Northern Apennine Mountains), which has led to an increased awareness concerning this disease. The present study describes a further outbreak of bovine besnoitiosis in Italy. The afflicted herd was a dairy herd with no evidence for contact with cattle from regions known to be endemic for bovine besnoitiosis. The farm investigation was initiated after a three-year old Holstein Friesian dairy cow with generalized thickening and lichenification of the skin was diagnosed with bovine besnoitiosis. The clinical diagnosis was confirmed by gross pathology, histopathology, serology and PCR. Bradyzoites released from tissue cysts obtained from the skin of this animal enabled the first in vitro isolation of Besnoitia besnoiti in Italy. This isolate was named Bb-Italy1. Sequencing of a 2118 bp spanning region including the complete internal transcribed spacer 1 and parts of the 18S and the 5.8S rRNA gene from DNA extracted from skin-derived zoites revealed a 99.9% identity to sequences known for other B. besnoiti isolated from cattle in Europe. Two GKO mice which had been inoculated intraperitoneally with bovine skin-derived bradyzoites became ill 7 days post inoculation. Parasitophorous vacuoles with multiplying zoites were observed in the cell culture inoculated with peritoneal fluids of these mice and a B. besnoiti infection in the mice and in the cell culture could be confirmed by real-time PCR. A serological investigation in the afflicted herd using immunoblots and an immunofluorescent antibody test (IFAT) revealed an overall herd seroprevalence of 9.7% (31/321), whereas within the female animals older than 2

Work-Related Eye Injuries: A Relevant Health Problem. Main Epidemiological Data from a Highly-Industrialized Area of Northern Italy.

PubMed

Gobba, Fabriziomaria; Dall'Olio, Enrico; Modenese, Alberto; De Maria, Michele; Campi, Luca; Cavallini, Gian Maria

2017-06-06

The province of Modena is one of the most industrialized areas of Northern Italy. The medical records of the Ophthalmological Emergency Department (OED) of Modena University Hospital were studied: there were 13,470 OED accesses in 2014 and in 754 cases that an occupational eye injury occurred. The frequency of work-related eye injuries (3‰) was lower compared to other published studies, but the absolute number is still relevant, showing the need for more adequate prevention, especially in metal work, construction work, and agriculture, where the worst prognoses were observed. Intervention programs must be implemented as early as possible in the working life, considering that the frequency in younger workers is about double that of the oldest age class (3.5‰ vs. 1.8‰), and special attention should also be given to foreigners, who have a 50% higher injury risk. Furthermore, the planning of specific interventions for eye-injured workers may be useful, considering that a previous injury does not appear to encourage the adoption of preventive interventions, and a subgroup of eye-injured workers have a potential risk for new injuries. Finally, the data presented here indicates how OED records, integrated with specific occupational information, can be applied for studies on work-related eye injuries.

Spread of plant pathogens and insect vectors at the northern range margin of cypress in Italy

NASA Astrophysics Data System (ADS)

Zocca, Alessia; Zanini, Corrado; Aimi, Andrea; Frigimelica, Gabriella; La Porta, Nicola; Battisti, Andrea

2008-05-01

The Mediterranean cypress ( Cupressus sempervirens) is a multi-purpose tree widely used in the Mediterranean region. An anthropogenic range expansion of cypress has taken place at the northern margin of the range in Italy in recent decades, driven by ornamental planting in spite of climatic constraints imposed by low winter temperature. The expansion has created new habitats for pathogens and pests, which strongly limit tree survival in the historical (core) part of the range. Based on the enemy release hypothesis, we predicted that damage should be lower in the expansion area. By comparing tree and seed cone damage by pathogens and pests in core and expansion areas of Trentino, a district in the southern Alps, we showed that tree damage was significantly higher in the core area. Seed cones of C. sempervirens are intensively colonized by an aggressive and specific pathogen (the canker fungus Seiridium cardinale, Coelomycetes), associated with seed insect vectors Megastigmus wachtli (Hymenoptera Torymidae) and Orsillus maculatus (Heteroptera Lygaeidae). In contrast, we observed lower tree damage in the expansion area, where a non-aggressive fungus ( Pestalotiopsis funerea, Coelomycetes) was more frequently associated with the same insect vectors. Our results indicate that both insect species have a great potential to reach the range margin, representing a continuous threat of the arrival of fungal pathogens to trees planted at extreme sites. Global warming may accelerate this process since both insects and fungi profit from increased temperature. In the future, cypress planted at the range margin may then face similar pest and pathogen threats as in the historical range.

The 2012 Emilia seismic sequence (Northern Italy): Imaging the thrust fault system by accurate aftershock location

NASA Astrophysics Data System (ADS)

Govoni, Aladino; Marchetti, Alessandro; De Gori, Pasquale; Di Bona, Massimo; Lucente, Francesco Pio; Improta, Luigi; Chiarabba, Claudio; Nardi, Anna; Margheriti, Lucia; Agostinetti, Nicola Piana; Di Giovambattista, Rita; Latorre, Diana; Anselmi, Mario; Ciaccio, Maria Grazia; Moretti, Milena; Castellano, Corrado; Piccinini, Davide

2014-05-01

Starting from late May 2012, the Emilia region (Northern Italy) was severely shaken by an intense seismic sequence, originated from a ML 5.9 earthquake on May 20th, at a hypocentral depth of 6.3 km, with thrust-type focal mechanism. In the following days, the seismic rate remained high, counting 50 ML ≥ 2.0 earthquakes a day, on average. Seismicity spreads along a 30 km east-west elongated area, in the Po river alluvial plain, in the nearby of the cities Ferrara and Modena. Nine days after the first shock, another destructive thrust-type earthquake (ML 5.8) hit the area to the west, causing further damage and fatalities. Aftershocks following this second destructive event extended along the same east-westerly trend for further 20 km to the west, thus illuminating an area of about 50 km in length, on the whole. After the first shock struck, on May 20th, a dense network of temporary seismic stations, in addition to the permanent ones, was deployed in the meizoseismal area, leading to a sensible improvement of the earthquake monitoring capability there. A combined dataset, including three-component seismic waveforms recorded by both permanent and temporary stations, has been analyzed in order to obtain an appropriate 1-D velocity model for earthquake location in the study area. Here we describe the main seismological characteristics of this seismic sequence and, relying on refined earthquakes location, we make inferences on the geometry of the thrust system responsible for the two strongest shocks.

Climate warming and the decline of Taxus airborne pollen in urban pollen rain (Emilia Romagna, northern Italy).

PubMed

Mercuri, A M; Torri, P; Casini, E; Olmi, L

2013-01-01

Woody plant performance in a changing global environment has always been at the centre of palaeoenvironmental and long-term climate reconstructions carried out by means of pollen analysis. In Mediterranean regions, Taxus constitutes the highest percentage in past pollen diagrams from cold or cool periods, and therefore it is generally considered a good index to infer climate features from past records. However, a comparison of these inferences with the true current trends in pollen production has not been attemped until now. This study reports the decline of airborne pollen of Taxus observed in Emilia Romagna, a region of northern Italy, during the period 1990-2007. Phenological observations on four male specimens and microscopic examination of fresh pollen were made in order to check Taxus flowering time and pollen morphology. Airborne pollen was monitored through continuous sampling with a Hirst volumetric sampler. In the 18-year long period of investigation, Taxus pollen production has decreased, while total woody pollen abundance in air has increased. The trend of the Taxus pollen season shows a delay at the beginning, a shortening of the pollen period, and an advance of the end of the pollen season. This was interpreted as a response to climate warming. In particular, Taxus follows the behaviour of winter-flowering plants, and therefore earlier pollination is favoured at low autumn temperatures, while late pollination occurs more often, most likely after warm autumn temperatures. © 2012 German Botanical Society and The Royal Botanical Society of the Netherlands.

Occupational injuries in Italy.

PubMed

Baldasseroni, Alberto; Chellini, Elisabetta; Mantero, Silvia; Giovannetti, Lucia

2005-01-01

Data collected by the Italian Funds for Occupational Injuries and Diseases (INAIL) on incidence and mortality for occupational injuries in Italy during 1951-2001 are described with respect to the two main occupational sectors, Industry and Services, and Agriculture. Comparisons with other EU countries are included to place the current severe phenomenon in context. An ad hoc analysis aimed at verifying the completeness of the data on occupational fatal accidents collected by INAIL in Tuscany is reported: a linkage between the INAIL data and those registered by the Tuscan Regional Mortality Registry highlights that a number of working areas are not covered by INAIL, a problem whose solution would be useful for primary prevention.

A life cycle assessment of non-renewable energy use and greenhouse gas emissions associated with blueberry and raspberry production in northern Italy.

PubMed

Girgenti, Vincenzo; Peano, Cristiana; Bounous, Michele; Baudino, Claudio

2013-08-01

This study examined the emissions produced during the pre-farm, farm and post-farm phases of the production cycle of raspberries and giant American whortleberries (blueberries) cultivated in one of the best-adapted areas in northern Italy. The pre-farm phase included the greenhouse gas emissions from the production of plants in the nursery and the transportation of the plants to the production farms. The farm phase involved the emissions of greenhouse gases from chemical products, the water used for irrigation, the generation of waste, and the consumption of electricity and other energy. The post-farm phase comprised the transportation of the products to the distribution centre (DC) and their storage in the DC. The use phase is not included in the system, nor is transportation from the supermarket to the home of the final consumer, but the disposal of the packaging is nevertheless taken into account. Indeed, the use of traditional plastic materials during both the field phase (nursery and cultivation) and the post-harvesting phase (packaging) produced the greatest estimated impact. Copyright © 2013 Elsevier B.V. All rights reserved.

Global alliance against chronic respiratory diseases in Italy (GARD-Italy): strategy and activities.

PubMed

Laurendi, Giovanna; Mele, Sonia; Centanni, Stefano; Donner, Claudio F; Falcone, Franco; Frateiacci, Sandra; Lazzeri, Marta; Mangiacavallo, Antonino; Indinnimeo, Luciana; Viegi, Giovanni; Pisanti, Paola; Filippetti, Giuseppe

2012-01-01

The steady increase in incidence of chronic respiratory disease (CRD) now constitutes a serious public health problem. CRDs are often underdiagnosed and many patients are not diagnosed until the CRD is too severe to prevent normal daily activities. The prevention of CRDs and reducing their social and individual impacts means modifying environmental and social factors and improving diagnosis and treatment. Prevention of risk factors (tobacco smoke, allergens, occupational agents, indoor/outdoor air pollution) will significantly impact on morbidity and mortality. The Italian Ministry of Health (MoH) has made respiratory disease prevention a top priority and is implementing a comprehensive strategy with policies against tobacco smoking, indoor/outdoor pollution, obesity, and communicable diseases. Presently these actions are not well coordinated. The Global Alliance against Chronic Respiratory Diseases (GARD), set up by the World Health Organization, envisages national bodies; the GARD initiative in Italy, launched 11/6/2009, represents a great opportunity for the MoH. Its main objective is to promote the development of a coordinated CRD program in Italy. Effective prevention implies setting up a health policy with the support of healthcare professionals and citizen associations at national, regional, and district levels. What is required is a true inter-institutional synergy: respiratory diseases prevention cannot and should not be the responsibility of doctors alone, but must involve politicians/policymakers, as well as the media, local institutions, and schools, etc. GARD could be a significant experience and a great opportunity for Italy to share the GARD vision of a world where all people can breathe freely. Copyright © 2011 Elsevier Ltd. All rights reserved.

Application of Skylab imagery to some geological and environmental problems in Italy. [and Sicily

NASA Technical Reports Server (NTRS)

Cassinis, R.; Lechi, G. M.; Tonelli, A. M.

1975-01-01

Four topics are considered: regional geology of Sicily, volcanic surveillance in southern Italy, hydrogeology (with special regard given to the discovery and mapping of paleoriverbeds), and crop investigation. The discovery of unknown lineaments and structures in Sicily contributes to the geological knowledge of this region and in particular to the mechanical phenomena involving the upper part of the crust. An attempt was made to relate the status of vegetation surrounding Etna volcano to the magmatic gas escapes filtering through the soil. False-color Skylab images were used to analyze the vigor of the Etnean forestal belt vegetation canopy in order to map possible gas-vent ways as well as the 'active' microfractures. In northern Italy, buried channels were mapped in the Venetian Plain, and a tentative cost-benefit evaluation was done in the field of vegetational studies, both disease detection and species inventory were performed in the Po River Delta and in northwestern Italy.

The Alcoholism Situation in a Northern City

ERIC Educational Resources Information Center

Martynov, M. Iu.; Martynova, D. Iu.

2012-01-01

Alcohol abuse in Russia has been increasing in recent years, especially in northern regions, as has the incidence of alcohol-related disease rates. A survey was conducted in Surgut (the Khanty-Mansi autonomous okrug) that determined the factors lending to the prevalence of alcohol abuse among the population of the northern city and assessed the…

Asbestiform minerals in ophiolitic rocks of Calabria (southern Italy).

PubMed

Campopiano, Antonella; Olori, Angelo; Spadafora, Alessandra; Rosaria Bruno, Maria; Angelosanto, Federica; Iannò, Antonino; Casciardi, Stefano; Giardino, Renato; Conte, Maurizio; Oranges, Teresa; Iavicoli, Sergio

2018-03-22

Ophiolitic rocks cropping on Calabria territory, southern Italy, can hold asbestiform minerals potentially harmful for human health. The aim of this work was to detect the fibrous phases of ophiolites along the Coastal Chain of northern Calabria and southern part of the Sila massif. Above 220 massive samples were collected in the study areas and analyzed using optical and electron microscopy, X-ray diffractometry, and Fourier transform infra-red spectrometry. The main fibrous constituent belonged to tremolite-actinolite series followed by fibrous antigorite that becomes more abundant in the samples collected in Reventino Mount surroundings. Results highlighted that serpentinites samples mainly consisted of antigorite and minor chrysotile. Samples collected along the coastal chain of northern Calabria did not hold fibrous materials. The results will be useful for Italian natural occurrences of asbestos (NOA) mapping in order to avoid an unintentional exposition by human activity or weathering processes.

Underreporting of congenital rubella in Italy, 2010-2014.

PubMed

Giambi, Cristina; Bella, Antonino; Filia, Antonietta; Del Manso, Martina; Nacca, Gloria; Declich, Silvia; Rota, Maria Cristina

2017-07-01

In accordance with the goals of the World Health Organization Regional Committee for Europe, the Italian national Measles and Rubella Elimination Plan 2010-2015 aimed to reduce the incidence of congenital rubella cases to <1 case/100,000 live births by 2015. In Italy, a passive national surveillance system for congenital rubella and rubella in pregnancy is active since 2005. We estimated the degree of underreporting of congenital rubella, performing a capture-recapture analysis of cases detected through two independent sources: the national surveillance system and the national hospital discharge database, in the years 2010-2014. We found that 6 out of 11 cases tracked in the retrospective case-finding from hospital registries had not been notified to the surveillance system, and we estimated a degree of underreporting of 53% for the period 2010-2014. This approach showed to be simple to perform, repeatable, and effective. In order to reduce underreporting, some actions aimed at strengthening surveillance procedures are needed. The adoption on a routine basis of the review of hospital discharge registries for case-finding, monthly zero-reporting, and actions to train and sensitize all the specialists involved in the care of pregnant women and the newborns to notification procedures are recommended. What is Known • In Italy, the incidence of congenital rubella was below the WHO target of 1/100,000 live births in 2005-2015, except for two peaks in 2008 and 2012 (5 and 4/100,000, respectively). • Further efforts are required to improve congenital rubella surveillance so that it is more sensitive and specific. The WHO proposes retrospective case-finding from hospital records as an alternative approach to detect infants with congenital rubella. What is New • Underreporting of congenital rubella in Italy was 53% in 2010-2014. • Hospital discharge registries resulted to be an appropriate source to detect congenital rubella cases.

Estimate of overdiagnosis of breast cancer due to mammography after adjustment for lead time. A service screening study in Italy

PubMed Central

Paci, Eugenio; Miccinesi, Guido; Puliti, Donella; Baldazzi, Paola; De Lisi, Vincenzo; Falcini, Fabio; Cirilli, Claudia; Ferretti, Stefano; Mangone, Lucia; Finarelli, Alba Carola; Rosso, Stefano; Segnan, Nereo; Stracci, Fabrizio; Traina, Adele; Tumino, Rosario; Zorzi, Manuel

2006-01-01

Introduction Excess of incidence rates is the expected consequence of service screening. The aim of this paper is to estimate the quota attributable to overdiagnosis in the breast cancer screening programmes in Northern and Central Italy. Methods All patients with breast cancer diagnosed between 50 and 74 years who were resident in screening areas in the six years before and five years after the start of the screening programme were included. We calculated a corrected-for-lead-time number of observed cases for each calendar year. The number of observed incident cases was reduced by the number of screen-detected cases in that year and incremented by the estimated number of screen-detected cases that would have arisen clinically in that year. Results In total we included 13,519 and 13,999 breast cancer cases diagnosed in the pre-screening and screening years, respectively. In total, the excess ratio of observed to predicted in situ and invasive cases was 36.2%. After correction for lead time the excess ratio was 4.6% (95% confidence interval 2 to 7%) and for invasive cases only it was 3.2% (95% confidence interval 1 to 6%). Conclusion The remaining excess of cancers after individual correction for lead time was lower than 5%. PMID:17147789

Prevalence and estimated incidence of blood-borne viral pathogen infection in organ and tissue donors from northern Alberta.

PubMed

Zahariadis, G; Plitt, S S; O'Brien, S; Yi, Q-L; Fan, W; Preiksaitis, J K

2007-01-01

To determine the potential safety benefit of introducing nucleic acid testing (NAT) in tissue and organ donors, the risk of virus transmission was examined in a Canadian population. Anonymous data on Northern Alberta tissue and organ donors from 1998 to 2004 were used to determine the seroprevalence and estimate the seroincidence and residual risk of HIV, HBV, HCV and HTLV infection. Of the 3372 donors identified, 71.1% were surgical bone, 13.2% were living organ and 15.6% were deceased organ/tissue donors. Seroprevalence was: HIV 0.00%, HBV 0.09%, HCV 0.48% and HTLV 0.03%. Incidence (/100,000 p-yrs) and residual risks (/100,000 donors) could only be estimated for HBV (24.2 and 3.9) and HCV (11.2 and 2.2). Risk estimates were higher for deceased donors than surgical bone donors. HCV had the highest prevalence and HBV had the highest estimated incidence. HIV and HTLV risks were extremely low precluding accurate quantification. In this region of low overall viral prevalence, HCV NAT would be most effective in deceased organ donors. In surgical bone donors the cost of implementing NAT is high without significant added safety benefit.

Estimating the incidence of connective tissue diseases and vasculitides in a defined population in Northern Savo area in 2010.

PubMed

Elfving, P; Marjoniemi, O; Niinisalo, H; Kononoff, A; Arstila, L; Savolainen, E; Rutanen, J; Kaipiainen-Seppänen, O

2016-07-01

Objective of the study was to evaluate the annual incidence and distribution of autoimmune connective tissue diseases and vasculitides during 2010. All units practicing rheumatology in the Northern Savo area, Finland, participated in the study by collecting data on newly diagnosed adult patients with autoimmune connective tissue disease or vasculitis over 1-year period. Seventy-two cases with autoimmune connective tissue disease were identified. The annual incidence rates were as follows: systemic lupus erythematosus 3.4/100,000 (95 % CI 1.4-7.0), idiopathic inflammatory myopathies 1.9 (0.5-5.0), systemic sclerosis 4.4 (2.0-8.3), mixed connective tissue disease 1.0 (0.1-3.5), Sjögren's syndrome 10.7 (6.7-16.1) and undifferentiated connective tissue disease 13.6 (9.0-19.6). The annual incidence rates among vasculitis category were as follows: antineutrophil cytoplasmic antibody-associated vasculitis 1.5/100,000 (95 % CI 0.3-4.3), central nervous system vasculitis 0.5 (0-2.7) and Henoch-Schönlein purpura 1.5 (0.3-4.3). The annual incidence of giant cell arteritis in the age group of 50 years or older was 7.5/100,000 (95 % CI 3.2-14.8). The longest delay from symptom onset to diagnosis occurred in systemic sclerosis. The incidences of autoimmune connective tissue diseases and vasculitides were comparable with those in published literature. The present study showed female predominance in all connective tissue diseases, excluding idiopathic inflammatory muscle diseases and mean age at onset of disease around 50 years of age. Despite improved diagnostic tools, diagnostic delay is long especially among patients with systemic sclerosis.

Long-term trends in first arrival and first egg laying dates of some migrant and resident bird species in northern Italy

NASA Astrophysics Data System (ADS)

Rubolini, Diego; Ambrosini, Roberto; Caffi, Mario; Brichetti, Pierandrea; Armiraglio, Stefano; Saino, Nicola

2007-08-01

Climate change is affecting the phenology of seasonal events in Europe and the Northern Hemisphere, as shown by several studies of birds’ timing of migration and reproduction. Here, we analyse the long-term (1982-2006) trends of first arrival dates of four long-distance migratory birds [swift ( Apus apus), nightingale ( Luscinia megarhynchos), barn swallow ( Hirundo rustica), and house martin ( Delichon urbicum)] and first egg laying dates of two migrant (swift, barn swallow) and two resident species [starling ( Sturnus vulgaris), Italian sparrow ( Passer italiae)] at a study site in northern Italy. We also addressed the effects of local weather (temperature and precipitation) and a climate index (the North Atlantic Oscillation, NAO) on the interannual variability of phenological events. We found that the swift and the barn swallow significantly advanced both arrival and laying dates, whereas all other species did not show any significant temporal trend in either arrival or laying date. The earlier arrival of swifts was explained by increasing local temperatures in April, whereas this was not the case for arrival dates of swallows and first egg laying dates of both species. In addition, arrival dates of house martins were earlier following high NAO winters, while nightingale arrival was earlier when local spring rainfall was greater. Finally, Italian sparrow onset of reproduction was anticipated by greater spring rainfall, but delayed by high spring NAO anomalies, and swift’s onset of reproduction was anticipated by abundant rainfall prior to reproduction. There were no significant temporal trends in the interval between onset of laying and arrival in either the swift or the barn swallow. Our findings therefore indicate that birds may show idiosyncratic responses to climate variability at different spatial scales, though some species may be adjusting their calendar to rapidly changing climatic conditions.

An integrated pest control strategy against the Asian tiger mosquito in northern Italy: a case study.

PubMed

Baldacchino, Frédéric; Bussola, Francesca; Arnoldi, Daniele; Marcantonio, Matteo; Montarsi, Fabrizio; Capelli, Gioia; Rosà, Roberto; Rizzoli, Annapaola

2017-01-01

In Europe, Aedes albopictus is an invasive mosquito species known to be a major nuisance as well as a vector of a range of arboviruses. A number of studies have indicated that community participation programmes are an effective pest control tool to reduce mosquito populations. However, few studies have evaluated the effectiveness of a community-based approach in Europe. In this study, we examined two Ae. albopictus control strategies that implemented a community-based approach in northern Italy: one was a partial intervention that included a public education campaign and the larviciding of public spaces, and the other was a full intervention that additionally included a door-to-door campaign. This latter consisted of going door to door actively to educate residents about control measures and deliver larvicide tablets for treating catch basins at home. A site where no intervention measures were carried out was used as a control. In the site where a full intervention was carried out, Ae. albopictus egg density was 1.6 times less than at the site that received partial intervention, and 1.9 times less than at the non-intervention site. No significant reduction in egg density was achieved in the partial intervention site. In our study, Ae. albopictus populations were most effectively reduced by larviciding both public and private catch basins. Door-to-door education was effective in convincing residents to apply control measures on their property; however, this method was labour intensive and costly. It may be possible to reduce personnel costs by involving volunteers or using a 'hot spot' approach. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

Emplacement of pyroclastic density currents (PDCs) in a deep-sea environment: The Val d'Aveto Formation case (Northern Apennines, Italy)

NASA Astrophysics Data System (ADS)

Di Capua, Andrea; Groppelli, Gianluca

2016-12-01

The occurrence of PDC deposits in a foredeep basin sequence, named Val d'Aveto Formation (32-29 Ma, Northern Apennines, Italy), provides new information on the behavior of pyroclastic density currents entering the water. In this work, stratigraphic, petrographic and mineralogical features that characterize three pyroclastic deposits have been described and analyzed in the field (facies and lithological analysis on the blocky-size fraction) and in the laboratory (image analyses on the blocky-size detritus, optical analyses of the microtextures, mineralogical analyses through X-ray powder diffraction (XRPD) and scanning electron microscope with energy dispersive X-ray spectometry (SEM-EDS). The deposits are lapilli- to blocky-size, with a blocky-size fraction constituted of accidental detritus. In thin sections, their groundmass texture varies from porphyritic to eutaxitic where coarser particles become close each others. Growth rims have been also detected around plagioclase crystals. Pyrite habits and oxidation, and plagioclase albitization are consistent with hydrothermal temperature conditions of 200 °C. All these results have been compared with the information provided by modern examples of PDC deposits and laboratory experiments on the behavior of water/hot particles mixing. Grain-to-grain collision has been considered as the main flow mechanism that sustained and avoided the disaggregation of the PDCs entering the water.

Traces of medieval migrations in a socially stratified population from Northern Italy. Evidence from uniparental markers and deep-rooted pedigrees

PubMed Central

Boattini, A; Sarno, S; Pedrini, P; Medoro, C; Carta, M; Tucci, S; Ferri, G; Alù, M; Luiselli, D; Pettener, D

2015-01-01

Social and cultural factors had a critical role in determining the genetic structure of Europe. Therefore, socially stratified populations may help to focus on specific episodes of European demographic history. In this study, we use uniparental markers to analyse the genetic structure of Partecipanza in San Giovanni in Persiceto (Northern Italy), a peculiar institution whose origins date back to the Middle Ages and whose members form the patrilineal descent of a group of founder families. From a maternal point of view (mtDNA), Partecipanza is genetically homogeneous with the rest of the population. However, we observed a significant differentiation for Y-chromosomes. In addition, by comparing 17 Y-STR profiles with deep-rooted paternal pedigrees, we estimated a Y-STR mutation rate equal to 3.90 * 10−3 mutations per STR per generation and an average generation duration time of 33.38 years. When we used these values for tentative dating, we estimated 1300-600 years ago for the origins of the Partecipanza. These results, together with a peculiar Y-chromosomal composition and historical evidence, suggest that Germanic populations (Lombards in particular) settled in the area during the Migration Period (400–800 AD, approximately) and may have had an important role in the foundation of this community. PMID:25204305

Traces of medieval migrations in a socially stratified population from Northern Italy. Evidence from uniparental markers and deep-rooted pedigrees.

PubMed

Boattini, A; Sarno, S; Pedrini, P; Medoro, C; Carta, M; Tucci, S; Ferri, G; Alù, M; Luiselli, D; Pettener, D

2015-02-01

Social and cultural factors had a critical role in determining the genetic structure of Europe. Therefore, socially stratified populations may help to focus on specific episodes of European demographic history. In this study, we use uniparental markers to analyse the genetic structure of Partecipanza in San Giovanni in Persiceto (Northern Italy), a peculiar institution whose origins date back to the Middle Ages and whose members form the patrilineal descent of a group of founder families. From a maternal point of view (mtDNA), Partecipanza is genetically homogeneous with the rest of the population. However, we observed a significant differentiation for Y-chromosomes. In addition, by comparing 17 Y-STR profiles with deep-rooted paternal pedigrees, we estimated a Y-STR mutation rate equal to 3.90 * 10(-3) mutations per STR per generation and an average generation duration time of 33.38 years. When we used these values for tentative dating, we estimated 1300-600 years ago for the origins of the Partecipanza. These results, together with a peculiar Y-chromosomal composition and historical evidence, suggest that Germanic populations (Lombards in particular) settled in the area during the Migration Period (400-800 AD, approximately) and may have had an important role in the foundation of this community.

Land use changes and its climatic implications in Northern Italy during the Dark Ages

NASA Astrophysics Data System (ADS)

Oeggl, Klaus; Oeggl-Wahlmüller, Notburga; Festi, Daniela; Zagermann, Marcus

2016-04-01

Here we present an interdisciplinary study on land use changes in Northern Italy at the transition from the Roman Empire to the Early Middle Ages. The combination of archaeological data and high-resolution pollen analyses carried out in the Fiavè basin (Trentino) provide a detailed insight in socio-economic changes and its implications with climate in the Dark Ages. The vegetation in this area is dominated up to 1000 m by submediterranian trees like Fraxinus ornus and Ostrya carpinifolia, superseded by a mixed Fagus and Abies forest with variable amounts of Picea abies. Since 2008 archaeological surveys in the Fiavè basin as well as excavations conducted on a fortified hill-top settlement (castrum) in 985m register the settlement development of this settlement cluster and reveal an almost continuous occupation from Roman to Early Medieval Times. In addition a high-resolution pollen record from a 1.30 m thick peat sequence of the bog "Palude di Fiave" discloses four main phases: (1) in the Late Iron Age high amounts of arboreal pollen and the spread of Abies demonstrate a decrease in settlement activity suggested by wetter climate conditions. (2) During the Roman Empire a phase with arable farming in the basin starts. Olea, Juglans and Castanea sativa are introduced and document the onset of horticulture in this region. (3) After 300 AD - during the Migration Period - the wet and cool conditions have had poor impact on settlement activity. Agricultural (Cerealia) and nitrophilous indicators (Plantago, Chenopodiaceae, Urticaceae) are continuously proved. However a change within the cultivated crops in relation to the climate conditions is observed. Subsequently a progressive recovery of Pinus followed by Abies and Fagus marks the climatic improvement at the beginning of the Early Medieval Times. (4) The time from 600 to 800 AD is characterized by increasing frequency and diversity of anthropogenic-related indicators. The implications of these land use changes with

Systematic detection and classification of earthquake clusters in Italy

NASA Astrophysics Data System (ADS)

Poli, P.; Ben-Zion, Y.; Zaliapin, I. V.

2017-12-01

We perform a systematic analysis of spatio-temporal clustering of 2007-2017 earthquakes in Italy with magnitudes m>3. The study employs the nearest-neighbor approach of Zaliapin and Ben-Zion [2013a, 2013b] with basic data-driven parameters. The results indicate that seismicity in Italy (an extensional tectonic regime) is dominated by clustered events, with smaller proportion of background events than in California. Evaluation of internal cluster properties allows separation of swarm-like from burst-like seismicity. This classification highlights a strong geographical coherence of cluster properties. Swarm-like seismicity are dominant in regions characterized by relatively slow deformation with possible elevated temperature and/or fluids (e.g. Alto Tiberina, Pollino), while burst-like seismicity are observed in crystalline tectonic regions (Alps and Calabrian Arc) and in Central Italy where moderate to large earthquakes are frequent (e.g. L'Aquila, Amatrice). To better assess the variation of seismicity style across Italy, we also perform a clustering analysis with region-specific parameters. This analysis highlights clear spatial changes of the threshold separating background and clustered seismicity, and permits better resolution of different clusters in specific geological regions. For example, a large proportion of repeaters is found in the Etna region as expected for volcanic-induced seismicity. A similar behavior is observed in the northern Apennines with high pore pressure associated with mantle degassing. The observed variations of earthquakes properties highlight shortcomings of practices using large-scale average seismic properties, and points to connections between seismicity and local properties of the lithosphere. The observations help to improve the understanding of the physics governing the occurrence of earthquakes in different regions.

A cross-sectional study of quality of life in incident stroke survivors in rural northern Tanzania.

PubMed

Howitt, Suzanne C; Jones, Matthew P; Jusabani, Ahmed; Gray, William K; Aris, Eric; Mugusi, Ferdinand; Swai, Mark; Walker, Richard W

2011-08-01

The aim of this study was to evaluate changes to, and predictors of, quality of life (QOL) in a community-based cohort of stroke survivors from an earlier stroke incidence study in rural northern Tanzania. Patients were assessed 1-5 years after their incident stroke. The study cohort was compared with an age- and sex-matched control group from the same rural district within a cross-sectional design. Patients and controls were asked a series of questions relating to their QOL [World Health Organization quality of life, abbreviated version (WHOQOL-BREF)], levels of anxiety and depression [hospital anxiety and depression (HAD) scale], cognitive function [community screening instrument for dementia (CSI-D) screening tool], socioeconomic status and demographic characteristics (e.g. age, sex, education and abode). Patients were further assessed for functional outcome and disability (Barthel index, modified Rankin scale), post-stroke care and psychosocial functioning. Patients (n = 58) were found to have significantly lower QOL than controls (n = 58) in all six domains of the WHOQOL-BREF. Gender, socioeconomic status, cognitive function and time elapsed since stroke were not associated with QOL. Older patients and those with more impaired motor function and disability (Barthel index, modified Rankin score) had significantly poorer physical health-related QOL. Greater anxiety and depression, reduced muscle power and less involvement in social events were significantly correlated with lower physical and psychological health-related QOL. To our knowledge, this is the first long-term study of QOL in survivors of incident stroke in Sub-Saharan Africa (SSA). Poorer QOL was associated with greater levels of physical disability, anxiety and depression and reduced social interaction. Demographic factors appear to be much less significant. Modifying these QOL predictors could be important in planning effective post-stroke care within a stretched healthcare system.

Seroprevalence of feline immunodeficiency virus, feline leukaemia virus and Toxoplasma gondii in stray cat colonies in northern Italy and correlation with clinical and laboratory data.

PubMed

Spada, Eva; Proverbio, Daniela; della Pepa, Alessandra; Perego, Roberta; Baggiani, Luciana; DeGiorgi, Giada Bagnagatti; Domenichini, Giulia; Ferro, Elisabetta; Cremonesi, Fausto

2012-06-01

Stray cat colonies in urban and rural areas of Lombardy, northern Italy, were surveyed for seroprevalence of feline immunodeficiency virus (FIV) antibodies, feline leukaemia virus (FeLV) antigen and Toxoplasma gondii IgG. Of 316 cats tested, 6.6% were positive for FIV and 3.8% were positive for FeLV infection; 203 cats were tested for T gondii IgG antibodies and a prevalence of 30.5% was detected. Statistical analysis tested the influence of provenience, age, gender, health status and laboratory results on seroprevalence and found male gender and adult age were risk factors for FIV infection. FIV-infected cats were more likely to have a decreased red blood cell count than FIV seronegative cats. No predictors were significantly associated with FeLV and T gondii seropositivity. Colony cats in this study posed a limited risk for retrovirus infection to pet cats allowed outdoors, whereas toxoplasmosis exposure was comparable with the worldwide data.

Molecular detection of Giardia duodenalis and Cryptosporidium spp. in canine faecal samples contaminating public areas in Northern Italy.

PubMed

Simonato, Giulia; Frangipane di Regalbono, Antonio; Cassini, Rudi; Traversa, Donato; Tessarin, Cinzia; Di Cesare, Angela; Pietrobelli, Mario

2017-12-01

Giardia duodenalis and Cryptosporidium spp. are common intestinal pathogens of humans and animals. Dogs may be infected by zoonotic isolates of G. duodenalis and Cryptosporidium spp. that, consequently, have high interest under public health perspective. This study estimated the occurrence of these protozoa in canine faeces polluting public areas of Padua municipality (Northern Italy), towards a potential evaluation of health risks for dogs and humans. A total of 705 canine stools was collected in green (n = 270) and urban (n = 435) areas and processed by duplex real-time PCR and real-time PCR SYBR® Green I for the detection of both protozoa. Positive samples were submitted to specific nested PCRs (i.e. β-giardin/SSU-rRNA genes for Giardia; SSU-rRNA gene for Cryptosporidium) to obtain detailed information on the isolates retrieved.Giardia and Cryptosporidium prevalence were 28.9% and 1.7%, respectively. Twenty-one Giardia-positive samples were successfully identified as dog-specific assemblages C and D, and 1 as the human-specific assemblage B. One isolate was identified as Cryptosporidium canis, while the other 11 were confirmed to belong to the Cryptosporidium parvum species complex. Contrariwise to the Cryptosporidium low prevalence, the wide distribution of Giardia suggests a high risk of infection for dogs attending public areas. Although data indicate a limited risk for human health, it is necessary to improve general education to reduce canine faecal pollution towards a widespread awareness of health risks.

Childhood asthma management pre- and post-incident asthma hospitalization.

PubMed

Bianchi, Marina; Clavenna, Antonio; Sequi, Marco; Bortolotti, Angela; Fortino, Ida; Merlino, Luca; Bonati, Maurizio

2013-01-01

Many hospitalizations for asthma could potentially be avoided with appropriate management. The aim of this study was to analyze data on disease management of a paediatric population with a hospitalization for asthma. The study population comprised 6-17 year old subjects belonging to three local health units of the Lombardy Region, northern Italy. Regional administrative databases were used to collect data on: the number of children with an incident hospitalization for asthma during the 2004-2006 period, anti-asthma therapy, specialist visit referrals, and claims for spirometry, released in the 12 months before and after hospitalization. Each patient's asthma management profile was compared with GINA guideline recommendations. Among the 183 hospitalized subjects, 101 (55%) received therapy before hospitalization and 82 (45%) did not. 10% did not receive any therapy either before or after hospital admission and in 13% the therapy was discontinued afterward. Based on GINA guidelines, asthma management adhered to recommendations only for 55% of subjects. Results may suggest that for half of hospitalized subjects, inaccurate diagnosis, under-treatment/scarce compliance with asthma guidelines by physicians, and/or scarce compliance to therapy by patients/their parents occurred. In all these cases, hospitalization would be a proxy indicator of preventable poor control of disease, rather than a proxy indicator of severity.

Strong motion recordings of the 2008/12/23 earthquake in Northern Italy: another case of very weak motion?

NASA Astrophysics Data System (ADS)

Sabetta, F.; Zambonelli, E.

2009-04-01

On December 23 2008 an earthquake of magnitude ML=5.1 (INGV) Mw=5.4 (INGV-Harvard Global CMT) occurred in northern Italy close to the cities of Parma and Reggio Emilia. The earthquake, with a macroseismic intensity of VI MCS, caused a very slight damage (some tens of unusable buildings and some hundreds of damaged buildings), substantially lower than the damage estimated by the loss simulation scenario currently used by the Italian Civil Protection. Due to the recent upgrading of the Italian strong motion network (RAN), the event has been recorded by a great number of accelerometers (the largest ever obtained in Italy for a single shock): 21 digital and 8 analog instruments with epicentral distances ranging from 16 to 140 km. The comparison of recorded PGA, PGV, Arias intensity, and spectral values with several widely used Ground Motion Prediction Equations (GMPEs) showed much lower ground motion values respect to the empirical predictions (a factor ranging from 4 to 2). A first explanation of the strong differences, in damage and ground motion, between actual data and predictions could be, at a first sight, attributed to the rather high focal depth of 27 km. However, even the adoption of GMPEs accounting for depth of the source and using hypocentral distance (Berge et al 2003, Pousse et al 2005), does not predict large differences in motions, especially at distances larger than 30 km where most of the data are concentrated and where the effect of depth on source-to-site distance is small. At the same time the adoption of the most recent GMPEs (Ambraseys et al 2005, Akkar & bommer 2007) taking into account the different magnitude scaling and the faster attenuation of small magnitudes through magnitude-dependent attenuation, does not show a better agreement with the recorded data. The real reasons of the above mentioned discrepancies need to be further investigated, however a possible explanation could be a low source rupture velocity, likewise the 2002 Molise

Epidemiological burden of postmenopausal osteoporosis in Italy from 2010 to 2020: estimations from a disease model.

PubMed

Piscitelli, P; Brandi, M; Cawston, H; Gauthier, A; Kanis, J A; Compston, J; Borgström, F; Cooper, C; McCloskey, E

2014-11-01

The article describes the adaptation of a model to estimate the burden of postmenopausal osteoporosis in women aged 50 years and over in Italy between 2010 and 2020. For this purpose, a validated postmenopausal osteoporosis disease model developed for Sweden was adapted to Italy. For each year of the study, the 'incident cohort' (women experiencing a first osteoporotic fracture) was identified and run through a Markov model using 1-year cycles until 2020. Health states were based on the number of fractures and deaths. Fracture by site (hip, clinical vertebral, non-hip non-vertebral) was tracked for each health state. Transition probabilities reflected fracture site-specific risk of death and subsequent fractures. Model inputs specific to Italy included population size and life tables from 1970 to 2020, incidence of hip fracture and BMD by age in the general population (mean and standard deviation). The model estimated that the number of postmenopausal osteoporotic women would increase from 3.3 million to 3.7 million between 2010 and 2020 (+14.3%). Assuming unchanged incidence rates by age group over time, the model predicted the overall number of osteoporotic fractures to increase from 285.0 to 335.8 thousand fractures between 2010 and 2020 (+17.8%). The estimated expected increases in hip, vertebral and non-hip non-vertebral fractures were 22.3, 17.2 and 16.3%, respectively. Due to demographic changes, the burden of fractures is expected to increase markedly by 2020.

Reduction in Neisseria meningitidis infection in Italy after Meningococcal C conjugate vaccine introduction: A time trend analysis of 1994–2012 series

PubMed Central

de Waure, Chiara; Miglietta, Alessandro; Nedovic, Darko; Mereu, Giovanna; Ricciardi, Walter

2016-01-01

The incidence of invasive meningococcal disease (IMD) in Italy is among the lowest in Europe. Meningococcal C conjugate vaccine (MCC) was introduced in 2005 for 12 months old infants. The aim of this study was to describe the epidemiology of IMD in Italy from 1994 to 2012 and to evaluate the impact of MCC introduction. Data about Neisseria meningitidis (N. meningitidis) cases were drawn from the National Surveillance of Invasive Bacterial Diseases. The average incidence of IMD during 1994–2012 in Italy was 0.36 per 100,000 (95%CI 0.30; 0.40). N. meningitidis B was the most frequent serogroup and infants less than 12 months old were the most affected. Joinpoint analysis showed a statistically significant reduction in the incidence of N. meningitidis C related IMD after MCC introduction: the Annual Percentage Change declined from 21.8 (95%CI 15.1; 28.9) in 1994–2005 to −19.9 (95%CI −28.2; −10.7) afterwards. No changes were observed with respect to N. meningitidis B related IMD. Poisson regression showed a statistically significant reduction in the incidence of IMD both associated to N. meningitidis C (Incidence Rate Ratio 0.33; 95%CI 0.29; 0.37) and due to all serogroups (Incidence Rate Ratio 0.70; 95%CI 0.65; 0.75) in the post-vaccination period compared to the pre-vaccination one. On the other hand, the incidence of N. meningitidis B related IMD did not decrease. Our results suggest that MCC had an impact in decreasing the incidence of N. meningitidis C related IMD. However, data on typing are incomplete and efforts are needed to make them available for studying the need and the impact of other meningococcal vaccines. PMID:26308192

New results on the hydrodynamic behaviour of fossil Nummulites tests from two nummulite banks from the Bartonian and Priabonian of northern Italy

PubMed Central

Seddighi, Mona; Briguglio, Antonino; Hohenegger, Johann; Papazzoni, Cesare Andrea

2015-01-01

Settling velocities of 58 well-preserved tests of fossil Nummulites were experimentally determined using a settling tube. The tests were collected from the nummulite banks of Pederiva di Grancona (A forms of N. lyelli and N. striatus, Middle Eocene) and San Germano dei Berici (A and B forms of N. fabianii, Late Eocene), both in the Berici Mts. (Veneto, northern Italy). The data were compared with estimated settling velocities that the same specimens might have had in life conditions. This was done by reconstructing their densities simulating water-filled condition and, to simulate post-diagenetic effects, under calcite-filled condition. These simulations show that A and B forms, even if they greatly diverge in shape, volume and size, still possess comparable settling velocities, and that each nummulite bank is characterized by specific hydrodynamic parameters. The use of settling velocity as a parameter to quantify the hydrodynamic behaviour of particles in seawater enables estimation of palaeoenvironmental conditions such as depth, substrate and the energy scenario. Such information is useful in obtaining further insights into the genesis of nummulite banks, the autochthony or allochthony of which is still being debated. Our results point to an autochthonous interpretation. PMID:26681827

New results on the hydrodynamic behaviour of fossil Nummulites tests from two nummulite banks from the Bartonian and Priabonian of northern Italy.

PubMed

Seddighi, Mona; Briguglio, Antonino; Hohenegger, Johann; Papazzoni, Cesare Andrea

2015-09-01

Settling velocities of 58 well-preserved tests of fossil Nummulites were experimentally determined using a settling tube. The tests were collected from the nummulite banks of Pederiva di Grancona (A forms of N. lyelli and N. striatus, Middle Eocene) and San Germano dei Berici (A and B forms of N. fabianii, Late Eocene), both in the Berici Mts. (Veneto, northern Italy). The data were compared with estimated settling velocities that the same specimens might have had in life conditions. This was done by reconstructing their densities simulating water-filled condition and, to simulate post-diagenetic effects, under calcite-filled condition. These simulations show that A and B forms, even if they greatly diverge in shape, volume and size, still possess comparable settling velocities, and that each nummulite bank is characterized by specific hydrodynamic parameters. The use of settling velocity as a parameter to quantify the hydrodynamic behaviour of particles in seawater enables estimation of palaeoenvironmental conditions such as depth, substrate and the energy scenario. Such information is useful in obtaining further insights into the genesis of nummulite banks, the autochthony or allochthony of which is still being debated. Our results point to an autochthonous interpretation.

Mantle xenoliths from Marosticano area (Northern Italy): a comparison with Veneto Volcanic Province lithospheric mantle

NASA Astrophysics Data System (ADS)

Brombin, Valentina; Bonadiman, Costanza; Coltorti, Massimo

2016-04-01

redox conditions (Δlog fO2: +1.2 to -0.7, Ballhaus, 1991) to Lessinean and Val d'Adige xenoliths which may indicate a local oxidation of the mantle below this portion of VVP. References • Beccaluva L., Bianchini G., Bonadiman C., Coltorti M., Milani L., Salvini L., Siena F., Tassinari R. (2007). Intraplate lithospheric and sublithospheric components in the Adriatic domain: Nephelinite to tholeiite magma generation in the Paleogene Veneto Volcanic Province, Southern Alps. Geological Society of America, 131-152. • Beccaluva L., Bonadiman C., Coltorti M., Salvini L., Siena F. (2001). Depletion events, nature of metasomatizing agent and timing of enrichment processes in lithospheric mantle xenoliths from the Veneto Volcanic Province. Journal of Petrology, 42, 173-187. • Gasperini D., Bosch D., Braga R., Bondi M., Macera P., Morten L. (2006). Ultramafic xenoliths from the Veneto Volcanic Province (Italy): Petrological and geochemical evidence for multiple metasomatism of the SE Alps mantle lithospere. Geochemical Journal, 40, 377-404. • Siena F., Coltorti M. (1989). Lithospheric mantle evolution: evidences from ultramafic xenoliths in the Lessinean volcanics (Northern Itlay). Chemical Geology, 77, 347-364.

Current status and epidemiological observation of Thelazia callipaeda (Spirurida, Thelaziidae) in dogs, cats and foxes in Italy: a "coincidence" or a parasitic disease of the Old Continent?

PubMed

Otranto, Domenico; Ferroglio, Ezio; Lia, Riccardo P; Traversa, Donato; Rossi, Luca

2003-10-30

Thelazia callipaeda is a spirurid nematode which causes ocular infections in dogs and man and, occasionally, in cats, foxes and rabbits. The intermediate host and vector of T. callipaeda is unknown. For a long time T. callipaeda incidence was reported only from the Russian Federation and the Far East, but recently it has also been found in Italy. In order to investigate the spread of T. callipaeda in Italy, a survey was carried out in two sites, site A in the Piedmont region (North West Italy), and site B in the Basilicata region (Southern Italy). Dogs, cats and foxes in site A and dogs in site B were examined for eyeworms, using different procedures and timing. From January 1995 to August 2002, 91 dogs, 4 cats and 903 fox carcasses were examined in site A, and from October 1999 to January 2003, 443 dogs were examined in site B, and the eyeworms collected were identified using morphological keys. Twenty-one (23.07%) and 185 (41.76%) of the dogs from sites A and B, respectively, were found to be infected by eyeworms; furthermore, all the cats examined and 46 fox carcasses (5.1%) were positive for eyeworms. All the nematodes collected were identified as T. callipaeda. These results indicate that T. callipaeda is not confined to Eastern Europe and Asia, but that it has spread to the Old Continent, and to both Northern and Southern Italy. Considering the high prevalence of infected dogs reported in some municipalities (e.g. 60.14% of 138 dogs examined in a municipality from site B), it is assumed that one or more vectors are significantly present in the areas under investigation. Furthermore, there is good reason to believe that T. callipaeda is also present in other European countries. Speculation as to the origins of this parasitic infestation in Europe and the biology of T. callipaeda and its vector/s is also discussed.

Detection of Shiga toxin (Stx)-producing Escherichia coli (STEC) in bovine dairy herds in Northern Italy.

PubMed

Trevisani, M; Mancusi, R; Delle Donne, G; Bacci, C; Bassi, L; Bonardi, S

2014-08-01

The aim of this study was to monitor the presence of Shiga toxin (Stx)-producing Escherichia coli in dairy farms authorized to sell raw milk and other farms, located in the same area, which sell milk to industry or use it to produce Parmesan or Grana cheese. Our research was focused on the serogroups O157 and O26, which are the most common in human cases in Italy and genetic markers that characterize the strains that can cause hemorrhagic colitis and hemolytic uremic syndrome (EHEC) in humans. Overall, 255 bulk-milk and 225 milk filter samples were screened for the presence of Shiga toxin genes (stx1 and stx2), O157 and O26 serogroups by using PCR. The samples were collected in 193 bovine dairy farms located in Northern Italy, including 32 farms selling raw milk to consumers. According to the preliminary PCR screening test, 32 out of 255 (12.5%; CI95%, 8.7% to 17.3%) bulk milk samples and 68 out of 225 (30.2%; CI95%, 24.3% to 36.7%) milk filters were positive for stx genes. Of the 32 milk samples that were stx-positive, 4 (1.6%, CI95%, 0.4% to 4%) were also positive by PCR for the rfbEO157 gene and 6 (2.4%, CI95%, 0.9% to 5.1%) were positive for the wzxO26 gene. The culture detection method, which was based on the immunomagnetic separation, achieved isolation rates of E. coli serogroups O157 and O26 in 25-67% of the milk samples that tested positive by PCR for these serogroups. STEC O26 was detected in one milk filter (1.6%) from a farm that sells raw milk to consumers directly and one sample (1.4%) of bulk milk intended for pasteurization. The presence of STEC O157 was also detected in 2 milk filters (1.7%) from farms that use milk to produce Grana cheese. All the STEC stains O157 and O26 isolated carried the genes eae and espK and genes belonging to the pathogenicity island OI-122 (efa1/2, sen, pagC), which are markers suitable for screening the human virulent EHEC strains. These virulence markers were also detected in the three strains of stx-negative E. coli O

Improving Flood Damage Assessment Models in Italy

NASA Astrophysics Data System (ADS)

Amadio, M.; Mysiak, J.; Carrera, L.; Koks, E.

2015-12-01

The use of Stage-Damage Curve (SDC) models is prevalent in ex-ante assessments of flood risk. To assess the potential damage of a flood event, SDCs describe a relation between water depth and the associated potential economic damage over land use. This relation is normally developed and calibrated through site-specific analysis based on ex-post damage observations. In some cases (e.g. Italy) SDCs are transferred from other countries, undermining the accuracy and reliability of simulation results. Against this background, we developed a refined SDC model for Northern Italy, underpinned by damage compensation records from a recent flood event. Our analysis considers both damage to physical assets and production losses from business interruptions. While the first is calculated based on land use information, production losses are measured through the spatial distribution of Gross Value Added (GVA). An additional component of the model assesses crop-specific agricultural losses as a function of flood seasonality. Our results show an overestimation of asset damage from non-calibrated SDC values up to a factor of 4.5 for tested land use categories. Furthermore, we estimate that production losses amount to around 6 per cent of the annual GVA. Also, maximum yield losses are less than a half of the amount predicted by the standard SDC methods.

Reviewing the upper Pleistocene human footprints from the 'Sala dei Misteri' in the Grotta della Bàsura (Toirano, northern Italy) cave: An integrated morphometric and morpho-classificatory approach

NASA Astrophysics Data System (ADS)

Paolo Citton; Romano, Marco; Salvador, Isabella; Avanzini, Marco

2017-08-01

About thirty human footprints made approximately 12,000 years B.P. inside the 'Sala dei Misteri' Cave of Básura near Toirano, Liguria, northern Italy, were studied by standard ichnological analysis. Eleven of the best-preserved tracks were examined further using morpho-classificatory and morphometric approaches, in order to estimate the minimum number of trackmakers; biometric measurements were also used to tentatively determine their physical characteristics (e.g., height and age). Results indicate at least three different producers, two youths and the third of tender age. Analysis of the data demonstrate the power of 3D, of landmark-based morphometrics, and the utility of methods of forensic anthropology in the determination of human footprints. The study of the number of trackmakers using the principal component analysis (PCA) on 'multi-trampling' surfaces could represent a model in the ichnological study of cave sites.

"Willing to Pay?" Tax Compliance in Britain and Italy: An Experimental Analysis

PubMed Central

Zhang, Nan; Andrighetto, Giulia; Ottone, Stefania; Ponzano, Ferruccio; Steinmo, Sven

2016-01-01

As shown by the recent crisis, tax evasion poses a significant problem for countries such as Greece, Spain and Italy. While these societies certainly possess weaker fiscal institutions as compared to other EU members, might broader cultural differences between northern and southern Europe also help to explain citizens’ (un)willingness to pay their taxes? To address this question, we conduct laboratory experiments in the UK and Italy, two countries which straddle this North-South divide. Our design allows us to examine citizens’ willingness to contribute to public goods via taxes while holding institutions constant. We report a surprising result: when faced with identical tax institutions, redistribution rules and audit probabilities, Italian participants are significantly more likely to comply than Britons. Overall, our findings cast doubt upon “culturalist” arguments that would attribute cross-country differences in tax compliance to the lack of morality amongst southern European taxpayers. PMID:26919201

"Willing to Pay?" Tax Compliance in Britain and Italy: An Experimental Analysis.

PubMed

Zhang, Nan; Andrighetto, Giulia; Ottone, Stefania; Ponzano, Ferruccio; Steinmo, Sven

2016-01-01

As shown by the recent crisis, tax evasion poses a significant problem for countries such as Greece, Spain and Italy. While these societies certainly possess weaker fiscal institutions as compared to other EU members, might broader cultural differences between northern and southern Europe also help to explain citizens' (un)willingness to pay their taxes? To address this question, we conduct laboratory experiments in the UK and Italy, two countries which straddle this North-South divide. Our design allows us to examine citizens' willingness to contribute to public goods via taxes while holding institutions constant. We report a surprising result: when faced with identical tax institutions, redistribution rules and audit probabilities, Italian participants are significantly more likely to comply than Britons. Overall, our findings cast doubt upon "culturalist" arguments that would attribute cross-country differences in tax compliance to the lack of morality amongst southern European taxpayers.

Online participation in climate change adaptation: A case study of agricultural adaptation measures in Northern Italy.

PubMed

Bojovic, Dragana; Bonzanigo, Laura; Giupponi, Carlo; Maziotis, Alexandros

2015-07-01

The new EU strategy on adaptation to climate change suggests flexible and participatory approaches. Face-to-face contact, although it involves time-consuming procedures with a limited audience, has often been considered the most effective participatory approach. In recent years, however, there has been an increase in the visibility of different citizens' initiatives in the online world, which strengthens the possibility of greater citizen agency. This paper investigates whether the Internet can ensure efficient public participation with meaningful engagement in climate change adaptation. In elucidating issues regarding climate change adaptation, we developed an eParticipation framework to explore adaptation capacity of agriculture to climate change in Northern Italy. Farmers were mobilised using a pre-existing online network. First they took part in an online questionnaire for revealing their perceptions of and reactions to the impacts of ongoing changes in agriculture. We used these results to suggest a portfolio of policy measures and to set evaluation criteria. Farmers then evaluated these policy options, using a multi criteria analysis tool with a simple user-friendly interface. Our results showed that eParticipation is efficient: it supports a rapid data collection, while involving high number of participants. Moreover, we demonstrated that the digital divide is decreasingly an obstacle for using online spaces for public engagement. This research does not present eParticipation as a panacea. Rather, eParticipation was implemented with well-established participatory approaches to both validate the results and, consequently, communicate meaningful messages on local agricultural adaptation practices to regional decision-makers. Feedbacks from the regional decision-makers showed their interest in using eParticipation to improve communication with farmers in the future. We expect that, with further Internet proliferation, eParticipation may allow the inclusion of

Use of cognitive enhancement medication among northern Italian university students.

PubMed

Castaldi, Silvana; Gelatti, Umberto; Orizio, Grazia; Hartung, Uwe; Moreno-Londono, Ana Maria; Nobile, Marta; Schulz, Peter J

2012-06-01

This study assesses the use of cognitive enhancement medication among university students in Northern Italy. It was conducted as a cross-sectional analysis on the basis of a paper-and-pencil survey of 77 undergraduate students attending courses in the Faculty of Medicine of the University of Milan, Milano, Italy. Although the share of students who have taken cognitive enhancement medication themselves in the past is still small (16%), the use of these drugs is rather common and freely communicated in some social circles. Enhancing the ability to study outside of the class was students' primary motive for use. Students who think that there is no or an acceptable risk involved in cognitive enhancement medication are more likely to take drugs and dietary supplements than those who perceive the risk as high.

The structural hinge of a chain-foreland basin: Quaternary activity of the Pede-Apennine Thrust front (Northern Italy)

NASA Astrophysics Data System (ADS)

Maestrelli, Daniele; Benvenuti, Marco; Bonini, Marco; Carnicelli, Stefano; Piccardi, Luigi; Sani, Federico

2018-01-01

The Pede-Apennine margin (Northern Italy) is a major WNW-ESE-trending morpho-structural element that delimits the Po Plain to the southwest and consists of a system of southwest dipping thrusts, generally referred to as Pede-Apennine Thrust (PAT). The leading edge of the chain lies further north-east and is buried beneath the Plio-Quaternary marine and fluvial deposits of the Po Plain. Whereas the buried external thrust fronts are obvious active structures (as demonstrated by the 2012 Emilia earthquakes; e.g. Burrato et al., 2012), ongoing activity of the PAT is debated. Using a multidisciplinary approach that integrates structural, seismic, sedimentological and pedological field data, we describe the recent activity of the PAT structures in a sector of the Pede-Apennine margin between the Panaro and the Enza Rivers (Emilia-Romagna). We found that the PAT is emergent or sub-emergent and deforms Middle Pleistocene deposits. We also infer a more recent tectonic phase ( 60-80 ka) by Optically Stimulated Luminescence (OSL) dating of soil profiles that have been deformed by a recent reactivation of the PAT. Furthermore, we show evidence that the PAT and its external splay thrusts strongly influenced the drainage pattern, causing fluvial diversions and forcing paleo-rivers to develop roughly parallel to the margin. Finally, numerical Trishear modelling has been used to calculate deformation rates for the PAT along two transects. Extrapolated slip rates vary between 0.68 and 0.79 mm·yr- 1 for about the last 1.2-0.8 million years.

HLA-DRB1 alleles associated with polymyalgia rheumatica in northern Italy: correlation with disease severity

PubMed Central

Salvarani, C.; Boiardi, L.; Mantovani, V.; Ranzi, A.; Cantini, F.; Olivieri, I.; Bragliani, M.; Collina, E.; Macchioni, P.

1999-01-01

OBJECTIVE—To examine the association of HLA-DRB1 alleles with polymyalgia rheumatica (PMR) in a Mediterranean country and to explore the role of HLA-DRB1 genes in determining disease severity.
METHODS—A five year prospective follow up study of 92 consecutive PMR patients diagnosed by the secondary referral centre of rheumatology of Reggio Emilia, Italy was conducted. HLA-DRB1 alleles were determined in the 92 patients, in 29 DR4 positive rheumatoid arthritis (RA) patients, and in 148 controls from the same geographical area by polymerase chain reaction amplification and oligonucleotide hybridisation.
RESULTS—No significant differences were observed in the frequencies of HLA-DRB1 types and in the expression of HLA-DRB 70-74 shared motif between PMR and controls. The frequency of the patients with double dose of epitope was low and not significantly different in PMR and in controls. No significant differences in the distribution of HLA-DR4 subtypes were observed between DR4+ PMR, DR+ RA, and DR4+ controls. Results of the univariate analysis indicated that an erythrocyte sedimentation rate (ESR) at diagnosis > 72 mm 1st h, the presence of HLA-DR1, DR10, rheumatoid epitope, and the type of rheumatoid epitope were significant risk factors associated with relapse/recurrence. Cox proportional hazards modelling identified two variables that independently increased the risk of relapse/recurrence: ESR at diagnosis > 72 mm 1st h (RR=1.5) and type 2 (encoded by a non-DR4 allele) rheumatoid epitope (RR=2.7).
CONCLUSION—These data from a Mediterranean country showed no association of rheumatoid epitope with PMR in northern Italian patients. A high ESR at diagnosis and the presence of rheumatoid epitope encoded by a non-DR4 allele are independent valuable markers of disease severity.

 PMID:10225816

Sea-level rise along the Emilia-Romagna coast (Northern Italy) in 2100: scenarios and impacts

NASA Astrophysics Data System (ADS)

Perini, Luisa; Calabrese, Lorenzo; Luciani, Paolo; Olivieri, Marco; Galassi, Gaia; Spada, Giorgio

2017-12-01

As a consequence of climate change and land subsidence, coastal zones are directly impacted by sea-level rise. In some particular areas, the effects on the ecosystem and urbanisation are particularly enhanced. We focus on the Emilia-Romagna (E-R) coastal plain in Northern Italy, bounded by the Po river mouth to the north and by the Apennines to the south. The plain is ˜ 130 km long and is characterised by wide areas below mean sea level, in part made up of reclaimed wetlands. In this context, several morphodynamic factors make the shore and back shore unstable. During next decades, the combined effects of land subsidence and of the sea-level rise as a result of climate change are expected to enhance the shoreline instability, leading to further retreat. The consequent loss of beaches would impact the economy of the region, which is tightly connected with tourism infrastructures. Furthermore, the loss of wetlands and dunes would threaten the ecosystem, which is crucial for the preservation of life and the environment. These specific conditions show the importance of a precise definition of the possible local impacts of the ongoing and future climate variations. The aim of this work is the characterisation of vulnerability in different sectors of the coastal plain and the recognition of the areas in which human intervention is urgently required. The Intergovernmental Panel on Climate Change (IPCC) Fifth Assessment Report (AR5) sea-level scenarios are merged with new high-resolution terrain models, current data for local subsidence and predictions of the flooding model in_CoastFlood in order to develop different scenarios for the impact of sea-level rise projected to year 2100. First, the potential land loss due to the combined effect of subsidence and sea-level rise is extrapolated. Second, the increase in floodable areas as a result of storm surges is quantitatively determined. The results are expected to support the regional mitigation and adaptation

Italy Country Analysis Brief

EIA Publications

2016-01-01

Italy is the fourth largest energy consumer in Europe, after Germany, France, and United Kingdom. Italy's primary energy consumption is driven by oil and gas, which contributed to over three-quarters of Italy's total consumption. The remaining portion is made up of coal, hydro, and other renewable energy sources. Renewable energy sources, excluding hydroelectricity, have increased their share in Italy's energy consumption from less than 2% in 2005 to nearly 10% in 2015. As a net importer of crude oil and natural gas, Italy is heavily dependent on imports to meet about 90% of its oil and gas needs and to maintain its exports of refined petroleum products.

Concentrations of polychlorinated dibenzodioxins, polychlorodibenzofurans, and polychlorobiphenyls in women of reproductive age in Italy: A human biomonitoring study.

PubMed

Ingelido, Anna Maria; Abate, Vittorio; Abballe, Annalisa; Albano, Fulvia Lucia; Battista, Tatiana; Carraro, Valter; Conversano, Michele; Corvetti, Rosa; De Luca, Silvia; Franchini, Silva; Fulgenzi, Anna Rita; Giambanco, Laura; Iacovella, Nicola; Iamiceli, Anna Laura; Maiorana, Antonio; Maneschi, Francesco; Marra, Valentina; Pirola, Flavia; Porpora, Maria Grazia; Procopio, Enrico; Suma, Nicola; Valentini, Silvia; Valsenti, Luisa; Vecchiè, Valerio; De Felip, Elena

2017-04-01

Polychlorinated dibenzodioxins (PCDDs), polychlorodibenzofurans (PCDFs), and polychlorobiphenyls (PCBs) are persistent organic pollutants that represent a major concern for women of reproductive age because of the neurodevelopmental effects associated to perinatal exposure. This study was aimed at characterizing exposure of women of reproductive age to PCDDs, PCDFs, and PCBs as a function of residence in different Italian Regions, in areas at presumable different environmental contamination and human exposure to these pollutants. Study participants were enrolled in 2011-2012 in 6 Italian Regions representative of Northern, Central and Southern Italy; in each region, areas at presumed different exposure (rural, urban and industrial) were selected for enrolment. Each participant provided a serum sample for the analysis of PCDDs, PCDFs and PCBs. Median concentrations of PCDDs+PCDFs, DL-PCBs, NDL 6 -PCBs and NDL 9 -PCBs in serum samples were respectively 6.0 and 3.5 pgWHO-TE 05 /g fat, and 75 and 93ng/g fat. Age was the variable that most affected median serum concentrations. Age adjusted concentrations were found significantly different between geographical zones: women from Northern Italy showed the highest values, followed by Central and Southern Italy. PCDDs+PCDFs concentrations were significantly higher in the group of women residing in industrial areas compared to the group residing in rural areas. A clear diminishing temporal trend was observed compared to levels reported in previous studies. This study produced the largest dataset on serum concentrations of PCDDs, PCDFs and PCBs in women of childbearing age in Italy. confirmed that environmental and lifestyle factors may influence exposure to these contaminants and thereby the body burden. The observed marked temporal decline in body burden during three decades is in agreement with the general trend observed worldwide. Copyright © 2016 Elsevier GmbH. All rights reserved.

Reconstructing the recent West Nile virus lineage 2 epidemic in Europe and Italy using discrete and continuous phylogeography

PubMed Central

Veo, Carla; Ebranati, Erika; Carta, Valentina; Rovida, Francesca; Percivalle, Elena; Moreno, Ana; Lelli, Davide; Calzolari, Mattia; Lavazza, Antonio; Chiapponi, Chiara; Baioni, Laura; Capelli, Gioia; Ravagnan, Silvia; Da Rold, Graziana; Lavezzo, Enrico; Palù, Giorgio; Baldanti, Fausto; Barzon, Luisa; Galli, Massimo

2017-01-01

West Nile virus lineage 2 (WNV-2) was mainly confined to sub-Saharan Africa until the early 2000s, when it was identified for the first time in Central Europe causing outbreaks of human and animal infection. The aim of this study was to reconstruct the origin and dispersion of WNV-2 in Central Europe and Italy on a phylodynamic and phylogeographical basis. To this aim, discrete and continuous space phylogeographical models were applied to a total of 33 newly characterised full-length viral genomes obtained from mosquitoes, birds and humans in Northern Italy in the years 2013–2015 aligned with 64 complete sequences isolated mainly in Europe. The European isolates segregated into two highly significant clades: a small one including three sequences and a large clade including the majority of isolates obtained in Central Europe since 2004. Discrete phylogeographical analysis showed that the most probable location of the root of the largest European clade was in Hungary a mean 12.78 years ago. The European clade bifurcated into two highly supported subclades: one including most of the Central/East European isolates and the other encompassing all of the isolates obtained in Greece. The continuous space phylogeographical analysis of the Italian clade showed that WNV-2 entered Italy in about 2008, probably by crossing the Adriatic sea and reaching a central area of the Po Valley. The epidemic then spread simultaneously eastward, to reach the region of the Po delta in 2013, and westward to the border area between Lombardy and Piedmont in 2014; later, the western strain changed direction southward, and reached the central area of the Po valley once again in 2015. Over a period of about seven years, the virus spread all over an area of northern Italy by following the Po river and its main tributaries. PMID:28678837

Incidence, prevalence, costs and quality of care of type 1 diabetes in Italy, age 0-29 years: The population-based CINECA-SID ARNO Observatory, 2002-2012.

PubMed

Bruno, G; Pagano, E; Rossi, E; Cataudella, S; De Rosa, M; Marchesini, G; Miccoli, R; Vaccaro, O; Bonora, E

2016-12-01

To assess temporal trend in incidence (2003-12) and prevalence (2002-12) of type 1 diabetes in children and young adults, direct costs and selected indicators of quality of care under the coverage of the universalistic Italian National Health System (NHS). The ARNO Observatory, a healthcare monitoring system based on administrative data, identified a population-based multiregional cohort of subjects aged 0-29 years. Type 1 diabetes was defined by at least two prescriptions of insulin over 12 months and continuous insulin-treatment in the following year. Indicators of quality of care and directs costs were assessed in persons with diabetes and in people without diabetes, individually matched for age, gender and health unit (1:4 ratio). We identified 2357 incident cases of type 1 diabetes aged 0-29 years (completeness of ascertainment, 99%). Incidence rates were similar in ages 0-14 (15.8, 95% CI 14.9-16.8) and 15-29 years (16.3, 15.4-17.2), with no significant trend. Prevalence increased from 137 to 166.9/100,000, particularly in the age 15-29 years. Direct costs accounted for € 2117 in persons with diabetes and € 292 in control individuals. A statistically significant decreasing trend in hospitalization for acute complications was evident (p < 0.001), which was almost completely due to ketoacidosis. People with at least one HbA1c measurement over the year were 48.5%. We showed high incidence and increasing prevalence of type 1 diabetes in young adults in Italy, which impact on direct costs under the universalistic coverage of the NHS. Copyright © 2016 The Italian Society of Diabetology, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition, and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved.

Geomorphic and landform survey of Northern Appennine Range (NAR)

NASA Technical Reports Server (NTRS)

Marino, C. M. (Principal Investigator); Zilioli, E.

1977-01-01

The author has identified the following significant results. An approach to landslide hazard detection was developed through the analysis of satellite imagery (LANDSAT 2) showing many landslide areas that occur on marine silts and clays in northern Appennine Range in Italy. A landslide risk score was given for large areas by narrowing and extending well defined areas, whose behavior and reflectivity variation was due to upper surface changes. Results show that this methodology allows evolution pattern of clay outflows to be distinguished.

Geo-climatic heterogeneity in self-reported asthma, allergic rhinitis and chronic bronchitis in Italy.

PubMed

Pesce, G; Bugiani, M; Marcon, A; Marchetti, P; Carosso, A; Accordini, S; Antonicelli, L; Cogliani, E; Pirina, P; Pocetta, G; Spinelli, F; Villani, S; de Marco, R

2016-02-15

Several studies highlighted a great variability, both between and within countries, in the prevalence of asthma and chronic airways diseases. To evaluate if geo-climatic variations can explain the heterogeneity in the prevalence of asthma and respiratory diseases in Italy. Between 2006 and 2010, a postal screening questionnaire on respiratory health was administered to 18,357 randomly selected subjects, aged 20-44, living in 7 centers in northern, central, and southern Italy. A random-effects meta-analysis was fitted to evaluate the between-centers heterogeneity in the prevalence of asthma, asthma-like symptoms, allergic rhinitis, and chronic bronchitis (CB). A principal component analysis (PCA) was performed to synthetize the geo-climatic information (annual mean temperature, range of temperature, annual rainfalls, global solar radiations, altitude, distance from the sea) of all the 110 Italian province capital towns. The associations between these geo-climatic components obtained with PCA and the prevalence of respiratory diseases were analyzed through meta-regression models. 10,464 (57%) subjects responded to the questionnaire. There was a significant between-centers heterogeneity in the prevalence of asthma (I(2)=59.5%, p=0.022) and CB (I(2)=60.5%, p=0.019), but not in that of asthma-like symptoms or allergic rhinitis. Two independent geo-climatic components explaining together about 80% of the overall geo-climatic variability were identified: the first principally summarized the climatic variables; the second the topographic ones. Variations in the prevalence of asthma across centers were significantly associated with differences in the climatic component (p=0.017), but not with differences in the topographic one. Our findings suggest that climate play a role in determining the between-center heterogeneity in the prevalence of asthma in Italy, with higher prevalence in dry-hot Mediterranean climates, and lower in rainy-cold northern climates. Copyright © 2015

Incidence rates of in-hospital carpal tunnel syndrome in the general population and possible associations with marital status.

PubMed

Mattioli, Stefano; Baldasseroni, Alberto; Curti, Stefania; Cooke, Robin M T; Bena, Antonella; de Giacomi, Giovanna; dell'Omo, Marco; Fateh-Moghadam, Pirous; Melani, Carla; Biocca, Marco; Buiatti, Eva; Campo, Giuseppe; Zanardi, Francesca; Violante, Francesco S

2008-10-28

Carpal tunnel syndrome (CTS) is a socially relevant condition associated with biomechanical risk factors. We evaluated age-sex-specific incidence rates of in-hospital cases of CTS in central/northern Italy and explored relations with marital status. Seven regions were considered (overall population, 14.9 million) over 3-6-year periods between 1997 and 2002 (when out-of-hospital CTS surgery was extremely rare). Incidence rates of in-hospital cases of CTS were estimated based on 1) codified demographic, diagnostic and intervention data in obligatory discharge records from all Italian public/private hospitals, archived (according to residence) on regional databases; 2) demographic general population data for each region. We compared (using the chiscore test) age-sex-specific rates between married, unmarried, divorced and widowed subsets of the general population. We calculated standardized incidence ratios (SIRs) for married/unmarried men and women. Age-standardized incidence rates (per 100,000 person-years) of in-hospital cases of CTS were 166 in women and 44 in men (106 overall). Married subjects of both sexes showed higher age-specific rates with respect to unmarried men/women. SIRs were calculated comparing married vs unmarried rates of both sexes: 1.59 (95% confidence interval [95% CI], 1.57-1.60) in women, and 1.42 (95% CI, 1.40-1.45) in men. As compared with married women/men, widows/widowers both showed 2-3-fold higher incidence peaks during the fourth decade of life (beyond 50 years of age, widowed subjects showed similar trends to unmarried counterparts). This large population-based study illustrates distinct age-related trends in men and women, and also raises the question whether marital status could be associated with CTS in the general population.

Convolute laminations and load structures in turbidites as indicators of flow reflections and decelerations against bounding slopes. Examples from the Marnoso-arenacea Formation (northern Italy) and Annot Sandstones (south eastern France)

NASA Astrophysics Data System (ADS)

Tinterri, R.; Muzzi Magalhaes, P.; Tagliaferri, A.; Cunha, R. S.

2016-10-01

This work discusses the significance of particular types of soft-sediment deformations very common within turbidite deposits, namely convolute laminations and load structures. Detailed facies analyses of the foredeep turbidites in the Marnoso-arenacea Formation (northern Italy) and Annot Sandstones (south eastern France) show that these deformational structures tend to increase near morphological obstacles, concomitantly with contained-reflected beds. The lateral and vertical distribution of convolute laminae and load structures, as well as their geometry, has a well-defined depositional logic related to flow decelerations and reflections against bounding slopes. This evidence suggests an interaction between fine-grained sediment and the presence of morphologic relief, and impulsive and cyclic-wave loadings, which are produced by flow impacts or reflected bores and internal waves related to impinging bipartite turbidity currents.

Shipbuilding and mesothelioma in Monfalcone, Italy.

PubMed

Bianchi, Claudio; Bianchi, Tommaso

2012-01-01

The Monfalcone area, northeastern Italy, a small industrial district with large shipyards, shows a high incidence of asbestos-related mesothelioma. In order to reconstruct some features of the Monfalcone shipbuilding activity during World War II and its health effects, the shipyard roll were examined, and people hired in 1942 were identified. The list of 2,776 persons hired in 1942 was coupled with the Pathological Anatomy Units archives of the Monfalcone and the Trieste Hospitals. Eighteen of the above persons had been diagnosed with pleural mesothelioma in the period 1981-2005. Eight patients had their first exposure in 1942, and the others had histories of previous exposures. Of 557 persons aged 14-15 years in 1942, six had a diagnosis of pleural mesothelioma. Necropsy findings were available in 14 cases. The burdens of lung asbestos bodies, isolated in 11 cases, showed wide variation (from 150 to 600,000 bodies per gram of dried tissue). While probably underestimated, the present data indicate a high incidence of mesothelioma among the shipyard workers of Monfalcone.

Shipbuilding and mesothelioma in Monfalcone, Italy

PubMed Central

Bianchi, Claudio; Bianchi, Tommaso

2012-01-01

The Monfalcone area, northeastern Italy, a small industrial district with large shipyards, shows a high incidence of asbestos-related mesothelioma. In order to reconstruct some features of the Monfalcone shipbuilding activity during World War II and its health effects, the shipyard roll were examined, and people hired in 1942 were identified. The list of 2,776 persons hired in 1942 was coupled with the Pathological Anatomy Units archives of the Monfalcone and the Trieste Hospitals. Eighteen of the above persons had been diagnosed with pleural mesothelioma in the period 1981-2005. Eight patients had their first exposure in 1942, and the others had histories of previous exposures. Of 557 persons aged 14-15 years in 1942, six had a diagnosis of pleural mesothelioma. Necropsy findings were available in 14 cases. The burdens of lung asbestos bodies, isolated in 11 cases, showed wide variation (from 150 to 600,000 bodies per gram of dried tissue). While probably underestimated, the present data indicate a high incidence of mesothelioma among the shipyard workers of Monfalcone. PMID:23112501

Epidemiology of malignant mesothelioma in Italy: surveillance systems, territorial clusters and occupations involved

PubMed Central

Binazzi, Alessandra; Bonafede, Michela; Di Marzio, Davide; Scarselli, Alberto

2018-01-01

Background As a legacy of the large asbestos consumption until the definitive ban in 1992, Italy is currently suffering a severe epidemic of asbestos related diseases. The aim of this paper is to describe the surveillance system for mesothelioma incidence and to provide evidences regarding the occurrence of the disease in Italy and the circumstances of asbestos exposure. Methods Italian National Register of Malignant Mesotheliomas (ReNaM) is a permanent surveillance system of mesothelioma incidence, with Regional Operating Centres (CORs) active in each Italian region, identifying incident malignant mesothelioma (MM) cases from health care structures. Occupational history, lifestyle habits and residential history are obtained using a standardised questionnaire, administered by a trained interviewer, to the subject or to the next of kin. Descriptive epidemiological figures, occupations involved in exposures and territorial maps of MM cases have been produced. Results At December 2016, ReNaM has collected 27,356 MM cases for the incidence period between 1993 and 2015. The modalities of exposure to asbestos have been investigated for 21,387 (78%) and an occupational exposure has been defined for around 70% of interviewed cases (14,818). Non-occupational exposure is still relevant with 4.9% and 4.4% of cases for which respectively a familial exposure (due to the cohabitation with an occupational exposed subject) and an environmental exposure (due to the residence near a contaminated site) has been detected. Discussion The epidemiological surveillance of MM incident cases, by the means of a national register for estimating the occurrence of the disease and identifying the circumstances of asbestos exposure, is a relevant tool for preventing asbestos exposure, for supporting the effectiveness of insurance system and for estimating reliable epidemiological figures. PMID:29507789

Firearm-related deaths in Brescia (Northern Italy) between 1994 and 2006: a retrospective study.

PubMed

Verzeletti, Andrea; Astorri, Paolo; De Ferrari, Francesco

2009-08-01

This retrospective study analyzes post-mortem examination data of 164 firearm-related casualties recorded by the Brescia, Italy Institute of Forensic Medicine between the years 1994 and 2006. The following variables were considered: year, month and day of death, gender and age of the victim, manner of death (homicide, suicide, accidental), type of weapon used, anatomical site and number of wounds, scene of death, and, whenever requested by the local District Attorney's Office, results of the toxicological examinations conducted on the corpses of the deceased. In the County of Brescia, Italy, the 2006 firearm-related mortality rate amounted to 0.84 per 100,000 residents, with an average of 12.6 cases per year. The most common manner of death was suicide (60.4%), followed by homicide (35.9%) and accidental death (3.7%). Most victims were male, with an average age of 47.2 in cases of suicide, 37.9 in cases of homicide, and 47.5 in cases of accidental death. Considering all of the death manners contemplated in this study, the weapon types most frequently resorted to were single-action, short-barrelled guns, followed by multiple-action, long-barrelled ones. In cases of suicide, entry wounds were primarily situated on the head (right temple) and chest (precordium), while in cases of homicide no conclusions could be drawn as to the entry wounds' predominant location.

Botulism in Italy, 1986 to 2015.

PubMed

Anniballi, Fabrizio; Auricchio, Bruna; Fiore, Alfonsina; Lonati, Davide; Locatelli, Carlo Alessandro; Lista, Florigio; Fillo, Silvia; Mandarino, Giuseppina; De Medici, Dario

2017-06-15

Botulism is a rare but severe neuroparalytic disease caused by botulinum toxins. Because of its high potential impact on public health, botulism is a closely monitored communicable disease in Europe. In Italy, which has one of the highest incidence rates in Europe (0.03 cases per 100,000 population), botulism is monitored through a case-based passive surveillance system: the front-line physician who diagnoses a suspected case must notify the Local Health Units immediately, and the Ministry of Health's office within 12 hours. From 1986 to 2015, 466 confirmed cases of botulism were recorded in Italy (of 1,257 suspected cases). Of these, 421 were food-borne (the most frequently seen form of botulism due to the consumption of improperly home-canned foods), 36 were infant botulism, which accounts for ca 50% of all these types of cases registered in Europe, six were wound-related and three were due to adult intestinal colonisation. This scenario suggests that stronger efforts should be made towards raising public awareness of the risk of food-borne botulism, especially with respect to home-preserved foods, as well as improving the training of front-line medical personnel, to ensure that a quick and accurate diagnosis of botulism can be made. This article is copyright of The Authors, 2017.

Botulism in Italy, 1986 to 2015

PubMed Central

Anniballi, Fabrizio; Auricchio, Bruna; Fiore, Alfonsina; Lonati, Davide; Locatelli, Carlo Alessandro; Lista, Florigio; Fillo, Silvia; Mandarino, Giuseppina; De Medici, Dario

2017-01-01

Botulism is a rare but severe neuroparalytic disease caused by botulinum toxins. Because of its high potential impact on public health, botulism is a closely monitored communicable disease in Europe. In Italy, which has one of the highest incidence rates in Europe (0.03 cases per 100,000 population), botulism is monitored through a case-based passive surveillance system: the front-line physician who diagnoses a suspected case must notify the Local Health Units immediately, and the Ministry of Health's office within 12 hours. From 1986 to 2015, 466 confirmed cases of botulism were recorded in Italy (of 1,257 suspected cases). Of these, 421 were food-borne (the most frequently seen form of botulism due to the consumption of improperly home-canned foods), 36 were infant botulism, which accounts for ca 50% of all these types of cases registered in Europe, six were wound-related and three were due to adult intestinal colonisation. This scenario suggests that stronger efforts should be made towards raising public awareness of the risk of food-borne botulism, especially with respect to home-preserved foods, as well as improving the training of front-line medical personnel, to ensure that a quick and accurate diagnosis of botulism can be made. PMID:28661393

Climatic Factors Driving Invasion of the Tiger Mosquito (Aedes albopictus) into New Areas of Trentino, Northern Italy

PubMed Central

Castellani, Cristina; Arnoldi, Daniele; Rizzoli, Annapaola

2011-01-01

Background The tiger mosquito (Aedes albopictus), vector of several emerging diseases, is expanding into more northerly latitudes as well as into higher altitudes in northern Italy. Changes in the pattern of distribution of the tiger mosquito may affect the potential spread of infectious diseases transmitted by this species in Europe. Therefore, predicting suitable areas of future establishment and spread is essential for planning early prevention and control strategies. Methodology/Principal Findings To identify the areas currently most suitable for the occurrence of the tiger mosquito in the Province of Trento, we combined field entomological observations with analyses of satellite temperature data (MODIS Land Surface Temperature: LST) and human population data. We determine threshold conditions for the survival of overwintering eggs and for adult survival using both January mean temperatures and annual mean temperatures. We show that the 0°C LST threshold for January mean temperatures and the 11°C threshold for annual mean temperatures provide the best predictors for identifying the areas that could potentially support populations of this mosquito. In fact, human population density and distance to human settlements appear to be less important variables affecting mosquito distribution in this area. Finally, we evaluated the future establishment and spread of this species in relation to predicted climate warming by considering the A2 scenario for 2050 statistically downscaled at regional level in which winter and annual temperatures increase by 1.5 and 1°C, respectively. Conclusions/Significance MODIS satellite LST data are useful for accurately predicting potential areas of tiger mosquito distribution and for revealing the range limits of this species in mountainous areas, predictions which could be extended to an European scale. We show that the observed trend of increasing temperatures due to climate change could facilitate further invasion of Ae. albopictus

Prevalence of prelingual deafness in Italy

PubMed Central

Bubbico, L; Rosano, A; Spagnolo, A

2007-01-01

(Basilicata, Calabria and Sicily). For the southern regions of Italy, the rate observed in the 50-64 and > 64 age groups reached 1.27 and 1.15, respectively. This phenomenon may have been due, in part, to the epidemic incidence of maternal rubella which occurred in the 40’s and 50’s (in Italy, the rubella vaccination was only recommended starting from 1972), and, in part, to the habit of contracting consanguineous marriages. Data from the Vatican Archives on 520,492 consanguineous marriages, for which dispensation was requested in the period 1911-1964, indicate that in the years 1935-1939, in small villages in South Italy (Basilicata, Calabria, Sicily) consanguineous marriages accounted for over 40% of marriages. PMID:17601206

Polychlorinated biphenyls (PCBs) in the atmosphere of sub-alpine northern Italy.

PubMed

Castro-Jiménez, J; Dueri, S; Eisenreich, S J; Mariani, G; Skejo, H; Umlauf, G; Zaldívar, J M

2009-03-01

The main objective of this work was to assess the atmospheric concentrations and seasonal variations of selected POPs in a sub-alpine location where few data are available. A monitoring and research station was set up at the JRC Ispra EMEP site (Italy). We present and discuss a one-year data set (2005-2006) on PCB air concentrations. Sigma 7PCBs monthly averaged concentration varied from 31 to 76 pgm(-3). Concentrations in the gas phase (21-72 pgm(-3)) were higher than those in the particulate phase (3-10 pgm(-3)). Advection of air masses and re-volatilization from local sources seem to play a dominant role as drivers of PCB atmospheric concentrations in the area. Indications of seasonal variation affecting PCB congener patterns and the gas/particulate partitioning were found. Modeling calculations suggest a predominant importance of the wet deposition in this region (1 microgm(-2)yr(-1) Sigma 7PCBs yearly total wet deposition flux; 650-2400 pgL(-1) rainwater concentrations).

Plant Responses to Climate Change: The Case Study of Betulaceae and Poaceae Pollen Seasons (Northern Italy, Vignola, Emilia-Romagna)

PubMed Central

Mercuri, Anna Maria; Torri, Paola; Fornaciari, Rita; Florenzano, Assunta

2016-01-01

Aerobiological data have especially demonstrated that there is correlation between climate warming and the pollination season of plants. This paper focuses on airborne pollen monitoring of Betulaceae and Poaceae, two of the main plant groups with anemophilous pollen and allergenic proprieties in Northern Italy. The aim is to investigate plant responses to temperature variations by considering long-term pollen series. The 15-year aerobiological analysis is reported from the monitoring station of Vignola (located near Modena, in the Emilia-Romagna region) that had operated in the years 1990–2004 with a Hirst spore trap. The Yearly Pollen Index calculated for these two botanical families has shown contrasting trends in pollen production and release. These trends were well identifiable but fairly variable, depending on both meteorological variables and anthropogenic causes. Based on recent reference literature, we considered that some oscillations in pollen concentration could have been a main effect of temperature variability reflecting global warming. The duration of pollen seasons of Betulaceae and Poaceae, depending on the different species included in each family, has not unequivocally been determined. Phenological responses were particularly evident in Alnus and especially in Corylus as a general moving up of the end of pollination. The study shows that these trees can be affected by global warming more than other, more tolerant, plants. The research can be a contribution to the understanding of phenological plant responses to climate change and suggests that alder and hazelnut trees have to be taken into high consideration as sensible markers of plant responses to climate change. PMID:27929423

Plant Responses to Climate Change: The Case Study of Betulaceae and Poaceae Pollen Seasons (Northern Italy, Vignola, Emilia-Romagna).

PubMed

Mercuri, Anna Maria; Torri, Paola; Fornaciari, Rita; Florenzano, Assunta

2016-12-06

Aerobiological data have especially demonstrated that there is correlation between climate warming and the pollination season of plants. This paper focuses on airborne pollen monitoring of Betulaceae and Poaceae, two of the main plant groups with anemophilous pollen and allergenic proprieties in Northern Italy. The aim is to investigate plant responses to temperature variations by considering long-term pollen series. The 15-year aerobiological analysis is reported from the monitoring station of Vignola (located near Modena, in the Emilia-Romagna region) that had operated in the years 1990-2004 with a Hirst spore trap. The Yearly Pollen Index calculated for these two botanical families has shown contrasting trends in pollen production and release. These trends were well identifiable but fairly variable, depending on both meteorological variables and anthropogenic causes. Based on recent reference literature, we considered that some oscillations in pollen concentration could have been a main effect of temperature variability reflecting global warming. The duration of pollen seasons of Betulaceae and Poaceae, depending on the different species included in each family, has not unequivocally been determined. Phenological responses were particularly evident in Alnus and especially in Corylus as a general moving up of the end of pollination. The study shows that these trees can be affected by global warming more than other, more tolerant, plants. The research can be a contribution to the understanding of phenological plant responses to climate change and suggests that alder and hazelnut trees have to be taken into high consideration as sensible markers of plant responses to climate change.

Endolithic microbial communities in carbonate precipitates from serpentinite-hosted hyperalkaline springs of the Voltri Massif (Ligurian Alps, Northern Italy).

PubMed

Quéméneur, Marianne; Palvadeau, Alexandra; Postec, Anne; Monnin, Christophe; Chavagnac, Valérie; Ollivier, Bernard; Erauso, Gaël

2015-09-01

The Voltri Massif is an ophiolitic complex located in the Ligurian Alps close to the city of Genova (Northern Italy) where several springs discharge high pH (up to 11.7), low salinity waters produced by the active serpentinization of the ultramafic basement. Mixing of these hyperalkaline waters with the river waters along with the uptake of atmospheric carbon dioxide forms brownish carbonate precipitates covering the bedrock at the springs. Diverse archaeal and bacterial communities were detected in these carbonate precipitates using 454 pyrosequencing analyses of 16S ribosomal RNA (rRNA) genes. Archaeal communities were dominated by members of potential methane-producing and/or methane-oxidizing Methanobacteriales and Methanosarcinales (Euryarchaeota) together with ammonia-oxidizing Nitrososphaerales (Thaumarchaeota) similar to those found in other serpentinization-driven submarine and terrestrial ecosystems. Bacterial communities consisted of members of the Proteobacteria, Actinobacteria, Planctomycetes, Bacteroidetes, Chloroflexi, and Verrucomicrobia phyla, altogether accounting for 92.2% of total retrieved bacterial 16S rRNA gene sequences. Amongst Bacteria, potential chemolithotrophy was mainly associated with Alpha- and Betaproteobacteria classes, including nitrogen-fixing, methane-oxidizing or hydrogen-oxidizing representatives of the genera Azospirillum, Methylosinus, and Hydrogenophaga/'Serpentinomonas', respectively. Besides, potential chemoorganotrophy was attributed mainly to representatives of Actinobacteria and Planctomycetales phyla. The reported 16S rRNA gene data strongly suggested that hydrogen, methane, and nitrogen-based chemolithotrophy can sustain growth of the microbial communities inhabiting the carbonate precipitates in the hyperalkaline springs of the Voltri Massif, similarly to what was previously observed in other serpentinite-hosted ecosystems.

Multidisciplinary approach to evaluate landslide susceptibility along highway in northern Calabria, Italy

NASA Astrophysics Data System (ADS)

Muto, Francesco; Conforti, Massimo; Critelli, Salvatore; Fabbricatore, Davide; Filomena, Luciana; Rago, Valeria; Robustelli, Gaetano; Scarciglia, Fabio; Versace, Pasquale

2014-05-01

The interaction of landslides with linear infrastructures is often the cause of disasters. In Italy landslide impact on roads, railways and buildings cause millions of Euro per year in damage and restoration as well. The proposed study is aimed to the landslide susceptibility evaluation using a multidisciplinary approach: geological and geomorphological survey, statistical analysis and GIS technique, along a section of highway "A3 (Salerno-Reggio Calabria)" between Cosenza Sud and Altilia, northern Calabria. This study is included in a wider research project, named: PON01-01503, Landslides Early Warning-Sistemi integrati per il monitoraggio e la mitigazione del rischio idrogeologico lungo le grandi vie di comunicazione - aimed at the hydrogeological risk mitigation and at the early warning along the highways. The work was first based on air-photo interpretations and field investigations, in order to realize the geological map, geomorphological map and landslide inventory map. In the study area the geomorphology is strongly controlled by its bedrock geology and tectonics. The bedrock geology consists of Neogene sedimentary rocks that cover a thick stack of allochthonous nappes. These nappes consist of crystalline rocks mainly gneiss, phyllite and schist. A total of 835 landslides were mapped and the type of movement are represented mainly by slides and complex and subordinately flow. In order to estimate and validate landslide susceptibility the landslides were divided in two group. One group (training set) was used to prepare susceptibility map and the second group (validation set) to validate the map. Then, the selection of predisposing factors was performed, according with the geological and geomorphological settings of the study area: lithology, distance from tectonic elements, land use, slope, aspect, stream power index (SPI) and plan curvature. In order to evaluate landslide susceptibility Conditional Analysis was applied to Unique Conditions Units (UCUs

Fusarium agapanthi sp. nov, a novel bikaverin and fusarubin-producing leaf and stem spot pathogen of Agapanthus praecox (African lily) from Australia and Italy

USDA-ARS?s Scientific Manuscript database

This study was conducted to characterize a novel Fusarium species that caused leaf and stem spot on Agapanthus praecox (Agapanthus, African lily) in northern Italy and leaf rot and spot on the same host in Melbourne, Australia. Formally described as Fusarium agapanthi, this pathogen was analyzed usi...

Exploring the variability in antibiotic prescribing profiles among paediatricians from two different areas of Italy.

PubMed

Cucinotta, Giovanni; Mazzaglia, Giampiero; Toscano, Maria A; Arcoraci, Vincenzo; Tempera, Gianna; Salmeri, Mario; Rosignoli, Mario; Bottaro, Gaetano; Boccazzi, Antonio; Nicoletti, Giuseppe; Caputi, Achille P

2002-05-01

We carried out a multicentre community-based study in order to describe the antibiotic therapeutic approach of paediatricians from two different areas of Italy in the treatment of respiratory tract infection (RTIs), and to assess which factors are involved in a possible variability of prescribing habits. Forty paediatricians participated in the study between October 1998 and April 1999. They had to complete a questionnaire for each therapeutic intervention resulting in an antibiotic prescription. A logistic regression model was used to identify possible predictors in choosing parenteral antibiotics for the treatment of RTIs. In 2 975 questionnaires of antibiotic treatment, RTIs represented 90.2% of the total antibiotics used. Upper respiratory tract infections were the most commonly treated diagnostic group (59.6%), followed by lower respiratory tract infections (20.4%), and middle ear infections (19.8%). Statistically significant differences between northern and southern Italy were reported in the antibiotic prescription profile and the duration of the therapy. Another marked difference was reported in the frequency of laboratory analysis requests. The logistic regression model indicated that the use of parenteral antibiotics appears significantly related to the type of infections [lower RTIs: (OR: 3.99; 95% CI: 2.49-6.37)], the geographic location [northern Italy: (OR: 0.20; 95% CI: 0.20-0.39)], and the presence of concurrent diseases (OR: 3.21; 95% CI: 1.46-7.02). The lack of adherence to clinical guidelines and the marked variability of antibiotic prescription rates between different areas of the country appear to be related to factors other than bacterial resistance, and highlight the importance of carrying out educational programmes targeted at the national level for improving the antibiotic prescription habits for the treatment of RTIs.

Geographic Variation in Cancer Incidence among Children and Adolescents in Taiwan (1995-2009).

PubMed

Hung, Giun-Yi; Horng, Jiun-Lin; Yen, Hsiu-Ju; Lee, Chih-Ying; Lee, Yu-Sheng

2015-01-01

Evidence from our recent study suggested that the overall trend for cancer incidence in children and adolescents has been increasing in Taiwan. To analyze geographic variations in this trend, cancer frequencies and incidence rates of disease groups were quantified according to geographic areas among 12,633 patients aged <20 years during 1995-2009 by using the population-based Taiwan Cancer Registry. Three geographic levels were defined, namely county or city, region (Northern, Central, Southern, and Eastern Taiwan), and local administrative area (special municipality, provincial city, county-administered city, township, and aboriginal area). Of the regions, Northern Taiwan had the highest incidence rate at 139.6 per million person-years, followed by Central (132.8), Southern (131.8), and Eastern (128.4) Taiwan. Significantly higher standardized rate ratios (SRRs) were observed in Northern Taiwan (SRR = 1.06, 95% confidence interval [CI] = 1.02-1.10) and at the township level (SRR = 1.07, 95% CI = 1.03-1.11). Of the cities or counties, New Taipei City yielded the highest SRR (1.08), followed by Taipei City (SRR = 1.07). A comparison of the rates in the four regions and the remainder of Taiwan according to cancer type revealed that only the rate of neuroblastomas in Eastern Taiwan was significantly low. Trend analysis showed that the most significant increase in incidence rate was observed at the township level, with an annual percent change of 1.8% during the 15-year study period. The high rate of childhood cancer in Northern Taiwan and at the township level deserves further attention. The potential impacts of environmental factors on the upward trend of childhood cancer incidence rate in townships warrant further investigation.

Birthdates of patients affected by mental illness and solar activity: A study from Italy

NASA Astrophysics Data System (ADS)

Ventriglio, Antonio; Borelli, Albacenzina; Bellomo, Antonello; Lepore, Alberto

2011-04-01

PurposeThis epidemiologic study tested an hypothesized association between the year of birth of persons with major mental illnesses and solar activity over the past century. MethodsWe collected data on diagnoses and birthdates of psychiatric patients born between 1926 and 1975 (N = 1954) in south Italy for comparison to yearly solar activity as registered by the International Observatories. ResultsWe found a strong inverse correlation between high solar activity (HSA) and incidence of schizophrenia and bipolar disorder in a 20-year period whereas the incidence of non-affective/non-psychotic disorders was moderately associated with HSA in the same period. ConclusionsInterpretation of the observed correlations between HSA during years of birth and the incidence of mental illnesses remains unclear, but the findings encourage further study.

Seasonal trends and environmental controls of methane emissions in a rice paddy field in Northern Italy

NASA Astrophysics Data System (ADS)

Meijide, A.; Manca, G.; Goded, I.; Magliulo, V.; di Tommasi, P.; Seufert, G.; Cescatti, A.

2011-12-01

Rice paddy fields are one of the greatest anthropogenic sources of methane (CH4), the third most important greenhouse gas after water vapour and carbon dioxide. In agricultural fields, CH4 is usually measured with the closed chamber technique, resulting in discontinuous series of measurements performed over a limited area, that generally do not provide sufficient information on the short-term variation of the fluxes. On the contrary, aerodynamic techniques have been rarely applied for the measurement of CH4 fluxes in rice paddy fields. The eddy covariance (EC) technique provides integrated continuous measurements over a large area and may increase our understanding of the underlying processes and diurnal and seasonal pattern of CH4 emissions in this ecosystem. For this purpose a Fast Methane Analyzer (Los Gatos Research Ltd.) was installed in a rice paddy field in the Po Valley (Northern Italy). Methane fluxes were measured during the rice growing season with both EC and manually operated closed chambers. Methane fluxes were strongly influenced by the height of the water table, with emissions peaking when it was above 10-12 cm. Soil temperature and the developmental stage of rice plants were also responsible of the seasonal variation on the fluxes. The measured EC fluxes showed a diurnal cycle in the emissions, which was more relevant during the vegetative period, and with CH4 emissions being higher in the late evening, possibly associated with higher water temperature. The comparison between the two measurement techniques shows that greater fluxes are measured with the chambers, especially when higher fluxes are being produced, resulting in 30 % higher seasonal estimations with the chambers than with the EC (41.1 and 31.7 g CH4 m-2 measured with chambers and EC respectively) and even greater differences are found if shorter periods with high chamber sampling frequency are compared. The differences may be a result of the combined effect of overestimation with the

Thallium-rich rust scales in drinkable water distribution systems: A case study from northern Tuscany, Italy.

PubMed

Biagioni, Cristian; D'Orazio, Massimo; Lepore, Giovanni O; d'Acapito, Francesco; Vezzoni, Simone

2017-06-01

Following the detection of a severe thallium contamination of the drinkable water from the public distribution system of Valdicastello Carducci-Pietrasanta (northern Tuscany, Italy), and the identification of the source of contamination in the Molini di Sant'Anna spring (average Tl content≈15μgL -1 ), the replacement of the contaminated water with a virtually Tl-free one (Tl<0.10μgL -1 ) caused an increase in Tl concentration in the drinkable water. This suggested that the pipeline interior had become a secondary source of Tl contamination, promoting its mineralogical and geochemical study. Rust scales samples taken from several pipeline segments, as well as leaching products obtained from these samples, were investigated through scanning electron microscopy, X-ray fluorescence chemical analyses, inductively coupled plasma - mass spectrometry, X-ray diffraction, and X-ray absorption spectroscopy. Thallium-rich rust scales (up to 5.3wt% Tl) have been found only in pipeline samples taken downstream the water treatment plant, whereas the sample taken upstream contains much less Tl (~90μgg -1 ). The Tl-rich nature of such scales is related to the occurrence of nano- and micro-spherules of Tl 2 O 3 and less abundant nanocrystalline μm-sized encrustations of TlCl. Leaching experiments on Tl-rich rust scales indicate that a fraction of the available Tl is easily dissolved in tap water; X-ray absorption spectroscopy suggests that monovalent thallium occurs in water equilibrated with the rust scales, probably related to the dissolution of TlCl encrustations. Therefore, Tl dissolved as Tl + only in the water from the Molini di Sant'Anna spring was partially removed through oxidative precipitation of Tl 2 O 3 and precipitation of TlCl. This highlights the critical role played by the addition of chlorine-based oxidants in water treatment plants that could favour the deposition of Tl-rich coatings within the pipelines, giving rise to unexpected secondary sources of

[Cancer mortality of residents near a steel factory in Udine (Friuli Venezia Giulia Region, Northern Italy)].

PubMed

Castriotta, Luigi; Casetta, Anica; Barbone, Fabio

2016-01-01

to evaluate the association between distance of residence from a steel factory, a point source of air pollution within an industrial area in Udine (Friuli Venezia Giulia Region, Northern Italy), and cancer mortality. retrospective study. To evaluate the association between mortality rates and distance from the source, a Stone test analysis for all cases occurred in the entire area was conducted. The significance level was determined using Monte Carlo simulations. a GIS mapped residential history of Friuli Venezia Giulia population was completed. Among residents within 5 km from the principal industrial plant of the area from 1989 to 2012, deaths caused by cancer were selected. Furthermore, according to the prevalent wind direction, an analysis was conducted also in a subgroup of residents located into the South-Western quadrant. A set of 8 bands with increasing distance from the point-source was defined. The total population was 37,473 inhabitants. in each band, observed and expected cancer-related deaths (calculated on the basis of mortality rates in the entire area) and standardized mortality ratios (SMRs) were computed to test for decline in risk of mortality at different distances from the main chimney. Stone test, in which a decline in risk of disease with an increase in distance from the source of pollution is tested, was used. the risk for all cancers and lung cancer was higher than expected. For male residents located within 2 km into the South-Western quarter there were 21 observed deaths from lung cancer vs. 13 expected (SMR: 1.62; p-value=0.02). despite the fact that in the whole area cancer mortality is not increased, this study seems to support evidence of an excess of cancer deaths, especially lung cancer among males, near a steel factory. However, the study has limitations because of the small number of cases and the lack of individual exposure data and information about confounders (e.g., smoke habits and professional exposure). Therefore, a

Residential Proximity to Major Roadways and Risk of Incident Ischemic Stroke in NOMAS (The Northern Manhattan Study).

PubMed

Kulick, Erin R; Wellenius, Gregory A; Boehme, Amelia K; Sacco, Ralph L; Elkind, Mitchell S

2018-04-01

The evidence supporting the deleterious cardiovascular health effects of living near a major roadway is growing, although this association is not universal. In primary analyses, we hypothesized that residential proximity to a major roadway would be associated with incident ischemic stroke and that cardiovascular risk factors would modify that association. NOMAS (The Northern Manhattan Study) is an ongoing, population-based cohort study designed to measure cardiovascular risk factors, stroke incidence, and other outcomes in a multiethnic urban population. Recruitment occurred from 1993 to 2001 and participants are followed-up annually by telephone. Residential addresses at baseline were geocoded and Euclidean distance to nearest major roadway was estimated and categorized as in prior studies. We used Cox proportional hazard models to calculate hazard ratios and 95% confidence intervals for the association of this distance to incidence of stroke and other outcomes, adjusting for sociodemographic and cardiovascular risk factors, year at baseline, and neighborhood socioeconomic status. We assessed whether these associations varied by age, sex, smoking status, diabetes mellitus, and hypertension. During a median follow-up period of 15 years (n=3287), 11% of participants were diagnosed with ischemic stroke. Participants living <100 m from a roadway had a 42% (95% confidence interval, 1.01-2.02) higher rate of ischemic stroke versus those living >400 m away. This association was more pronounced among noncurrent smokers (hazard ratio, 1.54; 95% confidence interval, 1.05-2.26) and not evident among smokers (hazard ratio, 0.69; 95% confidence interval, 0.23-2.06). There was no clear pattern of association between proximity to major roadways and other cardiovascular events including myocardial infarction, all-cause death, or vascular death. In this urban multiethnic cohort, we found evidence supporting that within-city variation in residential proximity to major roadway is

Siderite deposits in northern Italy: Early Permian to Early Triassic hydrothermalism in the Southern Alps

NASA Astrophysics Data System (ADS)

Martin, Silvana; Toffolo, Luca; Moroni, Marilena; Montorfano, Carlo; Secco, Luciano; Agnini, Claudia; Nimis, Paolo; Tumiati, Simone

2017-07-01

We present a minero-petrographic, geochemical and geochronological study of siderite orebodies from different localities of the Southern Alps (northern Italy). Siderite occurs as veins cutting the Variscan basement and the overlying Lower Permian volcano-sedimentary cover (Collio Fm.), and as both veins and conformable stratabound orebodies in the Upper Permian (Verrucano Lombardo and Bellerophon Fms.) and Lower Triassic (Servino and Werfen Fms.) sedimentary sequences of the Lombardian and the Venetian Alps. All types of deposits show similar major- and rare-earth (REE)-element patterns, suggesting a common iron-mineralizing event. The compositions of coexisting siderite, Fe-rich dolomite and calcite suggest formation from hydrothermal fluids at relatively high temperature conditions (≥ 250 °C). Geochemical modelling, supported by REE analyses and by literature and new δ13C and δ18O isotopic data, suggests that fluids responsible for the formation of siderite in the Variscan basement and in the overlying Lower Permian cover were derived from dominant fresh water, which leached Fe and C from volcanic rocks (mainly rhyolites/rhyodacites) and organic carbon-bearing continental sediments. On the basis of U-Th-Pb microchemical dating of uraninite associated with siderite in the Val Vedello and Novazza deposits (Lombardian Alps), the onset of hydrothermalism is constrained to 275 ± 13 Ma (Early-Mid Permian), i.e., it was virtually contemporaneous to the plutonism and the volcanic-sedimentary cycle reported in the same area (Orobic Basin). The youngest iron-mineralizing event is represented by siderite veins and conformable orebodies hosted in Lower Triassic shallow-marine carbonatic successions. In this case, the siderite-forming fluids contained a seawater component, interacted with the underlying Permian successions and eventually replaced the marine carbonates at temperatures of ≥ 250 °C. The absence of siderite in younger rocks suggests an Early Triassic

Epidemiology of pertussis in Italy: disease trends over the last century.

PubMed

Gonfiantini, M V; Carloni, E; Gesualdo, F; Pandolfi, E; Agricola, E; Rizzuto, E; Iannazzo, S; Ciofi Degli Atti, M L; Villani, A; Tozzi, A E

2014-10-09

We reviewed the epidemiology of pertussis in Italy over the last 125 years to identify disease trends and factors that could have influenced these trends. We described mortality rates (1888-2012), case fatality rates (1925-2012), cumulative incidence rates (1925-2013) and age-specific incidence rates (1974-2013). We compared data from routine surveillance with data from a paediatric sentinel surveillance system to estimate under-notification. Pertussis mortality decreased from 42.5 per 100,000 population in 1890 to no reported pertussis-related death after 2002. Incidence decreased from 86.3 per 100,000 in 1927 to 1 per 100,000 after 2008. Vaccine coverage increased from 32.8% in 1993 to about 96% after 2006. As for under-notification, mean sentinel/routine surveillance incidence ratio increased with age (from 1.8 in <1 year-olds to 12.9 in 10-14 year-olds). Pertussis mortality decreased before the introduction of immunisation. Incidence has decreased only after the introduction of pertussis vaccine and in particular after the achievement of a high immunisation coverage with acellular vaccines. Routine surveillance does not show an increase in cumulative incidence nor in ≥ 15 year-olds as reported by other countries. Underrecognition because of atypical presentation and the infrequent use of laboratory tests may be responsible for under-notification, and therefore affect incidence reports and management of immunisation programmes.

Psychological distress and its correlates in secondary school students in Pavia, Italy.

PubMed

Marinoni, A; Degrate, A; Villani, S; Gerzeli, S

1997-10-01

Adolescence is a time of social as well as biological transition; nevertheless, there are very few epidemiological studies in this field in Italy. Therefore, we felt it would be useful to conduct a cross-sectional study on a sample of 1346 adolescents aged 14-19 years attending high schools in the Health Authority Area of Pavia (northern Italy) through a multi-dimensional approach, taking into consideration physical and psychological health, life habits, family environment and social life of teen-agers. We used a structured self-administered questionnaire consisting of 264 question items to achieve the study aim, which was to find the variables (among personal data, scholastic, family, relational characteristics and habits) correlated with psychological distress. The results showed that in this sample psychological distress (evaluated by GHQ-30) was significatively (p < 0.005) associated with female sex, problems with school friends and teachers, having at least one immigrant parent (from a region different from that of residence), little love for parents and poor parental psycho-physical health status, staying at home on the weekend, smoking and using psychoactive medicines.

Reconstruction of full glacial environments and summer temperatures from Lago della Costa, a refugial site in Northern Italy

NASA Astrophysics Data System (ADS)

Samartin, Stéphanie; Heiri, Oliver; Kaltenrieder, Petra; Kühl, Norbert; Tinner, Willy

2016-07-01

Vegetation and climate during the last ice age and the Last Glacial Maximum (LGM, ∼23,000-19,000 cal BP) were considerably different than during the current interglacial (Holocene). Cold climatic conditions and growing ice-sheets during the last glaciation radically reduced forest extent in Europe to a restricted number of so-called ;refugia;, mostly located in the southern part of the continent. On the basis of paleobotanical analyses the Euganian Hills (Colli Euganei) in northeastern Italy have previously been proposed as one of the northernmost refugia of temperate trees (e.g. deciduous Quercus, Tilia, Ulmus, Fraxinus excelsior, Acer, Abies alba, Fagus sylvatica, Carpinus and Castanea) in Europe. In this study we provide the first quantitative, vegetation independent summer air temperature reconstruction for Northern Italy spanning the time ∼31,000-17,000 cal yr BP, which covers the coldest periods of the last glacial, including the LGM and Heinrich stadials 1 to 3. Chironomids preserved in a lake sediment core from Lago della Costa (7m a.s.l.), a small lake at the south-eastern edge of the Euganean Hills, allowed quantitative reconstruction of Full and Late Glacial summer air temperatures using a combined Swiss-Norwegian temperature inference model based on chironomid assemblages from 274 lakes. Chironomid and pollen evidence from Lago della Costa derives from finely stratified autochthonous organic gyttja sediments, which excludes major sediment mixing or reworking. After reconstructing paleo-temperatures, we address the question whether climate conditions were warm enough to permit the local survival of temperate tree species during the LGM and whether local expansions and pollen-inferred contractions of temperate tree taxa coincided with chironomid-inferred climatic changes. Our results suggest that chironomids at Lago della Costa have responded to major climatic fluctuations such as temperature decreases during the LGM and Heinrich stadials. The

Sedimentological and geochronological evidences of anthropogenic impacts on river basins in the Northern Latium coastal area (Italy)

NASA Astrophysics Data System (ADS)

Piazzolla, Daniele; Paladini de Mendoza, Francesco; Scanu, Sergio; Marcelli, Marco

2015-04-01

In this work we aimed to compare sedimentological and geochronological data from three sediment core samples (MIG50, MRT50, and GRT50) taken in the Northern Latium (Italy) coastal area, at -50 m depth, to data regarding rainfall, river flows and the land use in the three most important hydrographic basins (Mignone, Marta and Fiora) and in the coastal area. Different trends of sediment mass accumulation rate (MAR) are detected in the three cores: a strongly increasing trend was identified in MIG50 and MRT50 cores while GRT50 doesn't show significant variation. Data from the sedimentological analysis of GRT50 core identify a progressive decrease in the sandy component, which declined from about 30% to the current level of 7% over the last 36 years, while MRT50 and MIG50 cores (mainly composed by pelitic fraction > 95%) showed slight variations of textural ratio between silt and clay. According to the general decrease of pluviometric trend observed in Italy, related to teleconnection pattern tendency (NAO), the statistical analysis of rain identified significative decrease only in the Fiora river basin, whereas in the other two locations the decrease was not as significant. Regarding the Fiora river flow, a significative decreasing trend of average flow is detected, while the flood regime remained unaffected over the past 30 years. The analysis of the land use shows that the human activities are increased of 6-10% over the available time steps (1990 - 2006) in Fiora and Mignone river basins, while the Marta river basin has a strong human impact since 1990 highligting more than 80% of artificial soil covering. The largest variation is observed on the Fiora basin (10%) where the antrhopic activities have expanded to an area of about 85 Km2. Moreover, in the last ten years a large beach nourishment in 2004 (570000 m3) and dredging activities in the early second half of 2000s (1000000 m3 moved) were performed in Marina di Tarquinia beach and in front of the Torrevaldaliga

[Naïve Bayes classification for classifying injury-cause groups from Emergency Room data in the Friuli Venezia Giulia region (Northern Italy)].

PubMed

Valent, Francesca; Clagnan, Elena; Zanier, Loris

2014-01-01

to assess whether Naïve Bayes Classification could be used to classify injury causes from the Emergency Room (ER) database, because in the Friuli Venezia Giulia Region (Northern Italy) the electronic ER data have never been used to study the epidemiology of injuries, because the proportion of generic "accidental" causes is much higher than that of injuries with a specific cause. application of the Naïve Bayes Classification method to the regional ER database. sensitivity, specificity, positive and negative predictive values, agreement, and the kappa statistic were calculated for the train dataset and the distribution of causes of injury for the test dataset. on 22.248 records with known cause, the classifications assigned by the model agreed moderately (kappa =0.53) with those assigned by ER personnel. The model was then used on 76.660 unclassified cases. Although sensitivity and positive predictive value of the method were generally poor, mainly due to limitations in the ER data, it allowed to estimate for the first time the frequency of specific injury causes in the Region. the model was useful to provide the "big picture" of non-fatal injuries in the Region. To improve the collection of injury data at the ER, the options available for injury classification in the ER software are being revised to make categories exhaustive and mutually exclusive.

Intestinal parasites of owned dogs and cats from metropolitan and micropolitan areas: prevalence, zoonotic risks, and pet owner awareness in northern Italy.

PubMed

Zanzani, Sergio Aurelio; Gazzonis, Alessia Libera; Scarpa, Paola; Berrilli, Federica; Manfredi, Maria Teresa

2014-01-01

Intestinal parasites of dogs and cats are cosmopolitan pathogens with zoonotic potential for humans. Our investigation considered their diffusion in dogs and cats from northern Italy areas, specifically the metropolitan area of Milan and two micropolitan areas of neighboring provinces. It included the study of the level of awareness in pet owners of the zoonotic potential from these parasites. A total of 409 fresh fecal samples were collected from household dogs and cats for copromicroscopic analysis and detection of Giardia duodenalis coproantigens. The assemblages of Giardia were also identified. A questionnaire about intestinal parasites biology and zoonotic potential was submitted to 185 pet owners. The overall prevalence of intestinal parasites resulted higher in cats (47.37%-60.42%) and dogs (57.41%-43.02%) from micropolitan areas than that from the metropolis of Milan (dogs: P = 28.16%; cats: P = 32.58 %). The zoonotic parasites infecting pets under investigation were T. canis and T. cati, T. vulpis, Ancylostomatidae, and G. duodenalis assemblage A. Only 49.19% of pet owners showed to be aware of the risks for human health from canine and feline intestinal parasites. Parasitological results in pets and awareness determination in their owners clearly highlight how the role of veterinarians is important in indicating correct and widespread behaviors to reduce risks of infection for pets and humans in urban areas.

Diagnosis and high incidence of hyperornithinemia-hyperammonemia-homocitrullinemia (HHH) syndrome in northern Saskatchewan.

PubMed

Sokoro, AbdulRazaq A H; Lepage, Joyce; Antonishyn, Nick; McDonald, Ryan; Rockman-Greenberg, Cheryl; Irvine, James; Lehotay, Denis C

2010-12-01

Mutations in the SLC25A15 gene, encoding the human inner mitochondrial membrane ornithine transporter, are thought to be responsible for hyperornithinemia-hyperammonemia-homocitrullinemia (HHH) syndrome, a rare autosomal recessive condition. HHH syndrome has been detected in several small, isolated communities in northern Saskatchewan (SK). To determine the incidence of HHH syndrome in these communities, a PCR method was set up to detect F188Δ, the common French-Canadian mutation. Neonatal blood spots collected from all newborns from the high risk area were genotyped for the F188Δ mutation for seven consecutive years. Using DNA analysis, we estimated that the heterozygote frequency for the mutant allele for HHH syndrome to be about 1 in 19 individuals, predicting one affected child with HHH syndrome for approximately every 1,500 individuals (1 in 1,550 live births; 1 child every 12 years) in this isolated population. The frequency for the mutant allele for HHH syndrome in this isolated community is probably the highest in the world for this rare disorder. We determined that ornithine levels, by tandem mass spectrometry, were not abnormal in newborns with F188Δ mutation, carriers and normals. Ornithine rises to abnormally high levels at some time after birth well past the time that the newborn screening blood spot is collected. The timing or the reasons for the delayed rise of ornithine in affected children with HHH syndrome have not been determined. Newborn screening for HHH Syndrome in this high risk population is only possible by detection of the mutant allele using DNA analysis.

Antigenic and genetic analyses of isolate APMV/wigeon/Italy/3920-1/2005 indicate that it represents a new avian paramyxovirus (APMV-12).

PubMed

Terregino, C; Aldous, E W; Heidari, A; Fuller, C M; De Nardi, R; Manvell, R J; Beato, M S; Shell, W M; Monne, I; Brown, I H; Alexander, D J; Capua, I

2013-11-01

Isolate wigeon/Italy/3920-1/2005 (3920-1) was obtained during surveillance of wild birds in November 2005 in the Rovigo province of Northern Italy and shown to be a paramyxovirus. Analysis of cross-haemagglutination-inhibition tests between 3920-1 and representative avian paramyxoviruses showed only a low-level relationship to APMV-1. Phylogenetic analysis of the whole genome and each of the six genes indicated that while 3920-1 grouped with APMV-1 and APMV-9 viruses, it was quite distinct from these two. In the whole-genome analysis, 3920-1 had 52.1 % nucleotide sequence identity to the closest APMV-1 virus, 50.1 % identity to the APMV-9 genome, and less than 42 % identity to representatives of the other avian paramyxovirus groups. We propose isolate wigeon/Italy/3920-1/2005 as the prototype strain of a further APMV group, APMV-12.

Global trends in testicular cancer incidence and mortality.

PubMed

Rosen, Alexandre; Jayram, Gautam; Drazer, Michael; Eggener, Scott E

2011-08-01

Epidemiologic studies on testicular cancer have focused primarily on European countries. Global incidence and mortality have been less thoroughly evaluated. Our goal was to gain a better understanding of the most recent global age-standardized incidence and mortality rates for testicular cancer and to use these values to estimate a region's health care quality. Age-standardized incidence rate (ASIR) and age-standardized mortality rate (ASMR) for testicular cancer were obtained for men of all ages in 172 countries by using the GLOBOCAN 2008 database, reflecting the annual rate of cancer incidence and mortality per 100,000 men. These data were evaluated on a regional level to compare incidence and mortality rates. Global plots of these values were constructed to better visualize geographic distributions. Finally, the ratio of ASIR to ASMR was calculated as a method to assess each region's proficiency in diagnosing and effectively treating testicular cancer. ASIR and ASMR were analyzed by region, and each region's ratio of ASIR to ASMR was calculated. Testicular cancer ASIR is highest in Western Europe (7.8%), Northern Europe (6.7%), and Australia (6.5%). Asia and Africa had the lowest incidence (<1.0%). ASMR was highest in Central America (0.7%), western Asia (0.6%), and Central and Eastern Europe (0.6%). Mortality was lowest in North America, Northern Europe, and Australia (0.1-0.2%). The ASIR-ASMR ratio was highest in Australia (65.0%) and lowest in western Africa (1.0%). National reporting systems varied by country, and data quality may have fluctuated between regions. Testicular cancer incidence remains highest in developed nations with primarily Caucasian populations. Variable ASIR-ASMR ratios suggest markedly different geographic-specific reporting mechanisms, access to care, and treatment capabilities. Copyright © 2011 European Association of Urology. Published by Elsevier B.V. All rights reserved.

[Herpes Zoster and its prevention in Italy. Scientific consensus statement].

PubMed

Franco, Elisabetta; Gabutti, Giovanni; Bonanni, Paolo; Conversano, Michele; Stefano Valente, Marco Ercolani; Ferro, Antonio; Icardi, Giancarlo; Antonio Volpi, Marzia Lazzari; Maggi, Stefania; Rossi, Alessandro; Scotti, Silvestro; Vitale, Francesco; Greco, Donato

2014-01-01

In this paper, an Italian group of experts presents a revision of the available data about epidemiology and prevention of Herpes Zoster (HZ). HZ is an acute viral diseases caused by the reactivation of Varicella Zoster Virus (VZV). HZ is characterized by neurological and dermatological symptoms with a dermatomeric localization. The reactivation of the virus from the latent status in the sensitive ganglia increases with age and failing cell mediated immunity. In Europe, more than 95% of adults presents antibodies against VZV. Incidence of HZ is similar all over the world, related to the age of the population: from 2-3/1000 persons/year in the age group 20 to 50 years to 5/1000 in the 60 years old, 6-7/1000 between 70 and 80 up to >1/100 in older than 80. In Italy, about 157,000 new cases of HZ are estimated every year with an incidence of 6.3/1000 persons/year mostly in older adults. Among the hospitalized cases, 60% are over 65 years of age. The more frequent and severe complication of HZ is post herpetic neuralgia (PHN), characterized by severe localized pain lasting at least 3 month after the beginning of the acute phase. The pain is responsible for a sharp decrease in the quality of life. In Europe, PHN is described in 2.6-27% of HZ cases. In Italy, data obtained by a network of General Practitioner show PHN in 20.6% of HZ patients, while 9.2% of the patients still presents PHN at 6 months. The more frequent localization is thoracic; when the virus reactivate at the level of the ophthalmic division of the trigeminal nerve most patients develop ocular complications. The clinical and therapeutical managements of HZ patients is difficult and the results are often poor. Prevention of HZ e PHN in the population over 50 years is possible using a live attenuated vaccine containing VZV (Oka/Merck strain, not less than 19.400 plaque forming units), available since 2006. Efficacy of anti-HZ vaccine was demonstrated in two large clinical trials that showed a 51

Ongoing outbreak with well over 4,000 measles cases in Italy from January to end August 2017 − what is making elimination so difficult?

PubMed Central

Filia, Antonietta; Bella, Antonino; Del Manso, Martina; Baggieri, Melissa; Magurano, Fabio; Rota, Maria Cristina

2017-01-01

We report an ongoing measles outbreak in Italy, with over 4,400 cases reported in 20 Regions from January to August 2017. Median age was 27 years, 88% of the cases were unvaccinated. The highest incidence was in infants below one year of age and 7% of cases occurred among healthcare workers. Three deaths occurred and two cases of encephalitis were reported. Wide immunity gaps and nosocomial transmission are major challenges to measles elimination in Italy. PMID:28933342

Estimation of grazing-induced erosion through remote-sensing technologies in the Autonomous Province of Trento, Northern Italy

NASA Astrophysics Data System (ADS)

Torresani, Loris; Prosdocimi, Massimo; Masin, Roberta; Penasa, Mauro; Tarolli, Paolo

2017-04-01

Grassland and pasturelands cover a vast portion of the Earth surface and are vital for biodiversity richness, environmental protection and feed resources for livestock. Overgrazing is considered one of the major causes of soil degradation worldwide, mainly in pasturelands grazed by domestic animals. Therefore, an in-depth investigation to better quantify the effects of overgrazing in terms of soil loss is needed. At this regard, this work aims to estimate the volume of eroded materials caused by mismanagement of grazing areas in the whole Autonomous Province of Trento (Northern Italy). To achieve this goal, the first step dealt with the analysis of the entire provincial area by means of freely available aerial images, which allowed the identification and accurate mapping of every eroded area caused by grazing animals. The terrestrial digital photogrammetric technique, namely Structure from Motion (SfM), was then applied to obtain high-resolution Digital Surface Models (DSMs) of two representative eroded areas. By having the pre-event surface conditions, DSMs of difference, namely DoDs, was computed to estimate the erosion volume and the average depth of erosion for both areas. The average depths obtained from the DoDs were compared and validated by measures taken in the field. A large amount of depth measures from different sites were then collected to obtain a reference value for the whole province. This value was used as reference depth for calculating the eroded volume in the whole province. In the final stage, the Connectivity Index (CI) was adopted to analyse the existing connection between the eroded areas and the channel network. This work highlighted that SfM can be a solid low-cost technique for the low-cost and fast quantification of eroded soil due to grazing. It can also be used as a strategic instrument for improving the grazing management system at large scales, with the goal of reducing the risk of pastureland degradation.

Estimating canine cancer incidence: findings from a population-based tumour registry in northwestern Italy.

PubMed

Baioni, Elisa; Scanziani, Eugenio; Vincenti, Maria Claudia; Leschiera, Mauro; Bozzetta, Elena; Pezzolato, Marzia; Desiato, Rosanna; Bertolini, Silvia; Maurella, Cristiana; Ru, Giuseppe

2017-06-28

Canine cancer registry data can be put to good use in epidemiological studies. Quantitative comparison of tumour types may reveal unusual cancer frequencies, providing directions for research and generation of hypotheses of cancer causation in a specific area, and suggest leads for identifying risk factors. Here we report canine cancer incidence rates calculated from a population-based registry in an area without any known specific environmental hazard. In its 90 months of operation from 2001 to 2008 (the observation period in this study), the population-based Piedmont Canine Cancer Registry collected data on 1175 tumours confirmed by histopathological diagnosis. The incidence rate was 804 per 100,000 dog-years for malignant tumours and 897 per 100,000 dog-years for benign tumours. Higher rates for all cancers were observed in purebred dogs, particularly in Yorkshire terrier and Boxer. The most prevalent malignant neoplasms were cutaneous mastocytoma and hemangiopericytoma, and mammary gland complex carcinoma and simplex carcinoma. The Piedmont canine cancer registry is one of few of its kind whose operations have been consistently supported by long-term public funding. The registry-based cancer incidence rates were estimated with particular attention to the validity of data collection, thus minimizing the potential for bias. The findings on cancer incidence rates may provide a reliable reference for comparison studies. Researches conducted on dogs, used as sentinels for community exposure to environmental carcinogens, can be useful to detect excess risks in the incidence of malignant tumours in the human population.

Rich and Well Educated: Are These Requirements Necessary to Claim Healthcare Tax Credits in Italy?

PubMed

Brenna, Elenka

2018-04-01

The paper investigates the use of healthcare tax credits (HTCs) in Italy through the analysis of a panel data, which provides information on individual income tax from 2008 to 2014. There is evidence of disparities in the per-capita HTCs between Northern and Southern regions, which need to be analyzed and addressed. The aim of the paper is to investigate the socioeconomic determinants in the use of Healthcare Tax Credits in Italy. A fixed effects Ordinary Least Square model is run to analyze the impact of selected socioeconomic variables on regional per capita HTCs, with a particular focus on the role of education. The results corroborate literature findings on the regressive effects of HTCs; they also provide highlights on the role of education in explaining the distribution of HTCs among Italian regions. Public money is reimbursed to regions where people are, on average, richer and better educated. More equitable objectives could be reached by allocating the same resources in the provision of services covered by the NHS.

High prevalence of Behçet's disease in southern Italy.

PubMed

Olivieri, Ignazio; Leccese, Pietro; Padula, Angela; Nigro, Angelo; Palazzi, Carlo; Gilio, Michele; D'Angelo, Salvatore

2013-01-01

This paper aims to estimate the prevalence of Behçet's disease (BD) in the city of Potenza, the regional capital of Basilicata (or Lucania) Region, in southern Italy. Patients with BD living in Potenza for at least 12 months prior to diagnosis were identified through the following sources: general practitioners, community-based specialists, San Carlo Hospital specialists, the Basilicata centralised index and the Basilicata database for rare diseases. All identified patients were contacted by phone and were recalled to our outpatient clinic for re-evaluation. Patients were classified as having complete BD if they met the International Study Group (ISG) criteria for BD. By surveying a population of 69.060 subjects, 13 patients with a diagnosis of BD were identified. All were white and Italian by descendent. Eleven out of these satisfied the ISG criteria and allowed us to obtain a prevalence rate of 15.9 per 100.000 (95%CI 8.9-28.5), which is the highest ever found value in Europe. This cross-sectional population-based study suggests that BD is more frequent in the southern part than in the northern part of Italy and confirms that the prevalence of the disease increases in a north-to-south manner within the European continent.

Geographic Variation in Cancer Incidence among Children and Adolescents in Taiwan (1995–2009)

PubMed Central

Hung, Giun-Yi; Horng, Jiun-Lin; Yen, Hsiu-Ju; Lee, Chih-Ying; Lee, Yu-Sheng

2015-01-01

Background Evidence from our recent study suggested that the overall trend for cancer incidence in children and adolescents has been increasing in Taiwan. Methods To analyze geographic variations in this trend, cancer frequencies and incidence rates of disease groups were quantified according to geographic areas among 12,633 patients aged <20 years during 1995–2009 by using the population-based Taiwan Cancer Registry. Three geographic levels were defined, namely county or city, region (Northern, Central, Southern, and Eastern Taiwan), and local administrative area (special municipality, provincial city, county-administered city, township, and aboriginal area). Results Of the regions, Northern Taiwan had the highest incidence rate at 139.6 per million person-years, followed by Central (132.8), Southern (131.8), and Eastern (128.4) Taiwan. Significantly higher standardized rate ratios (SRRs) were observed in Northern Taiwan (SRR = 1.06, 95% confidence interval [CI] = 1.02–1.10) and at the township level (SRR = 1.07, 95% CI = 1.03–1.11). Of the cities or counties, New Taipei City yielded the highest SRR (1.08), followed by Taipei City (SRR = 1.07). A comparison of the rates in the four regions and the remainder of Taiwan according to cancer type revealed that only the rate of neuroblastomas in Eastern Taiwan was significantly low. Trend analysis showed that the most significant increase in incidence rate was observed at the township level, with an annual percent change of 1.8% during the 15-year study period. Conclusions The high rate of childhood cancer in Northern Taiwan and at the township level deserves further attention. The potential impacts of environmental factors on the upward trend of childhood cancer incidence rate in townships warrant further investigation. PMID:26192415

Middle and Upper Eocene nummulite banks of Northern Italy: common traits and differences

NASA Astrophysics Data System (ADS)

Seddighi, M.; Papazzoni, C. A.

2012-04-01

The well-known genus Nummulites flourished in the stable, oligotrophic environments of Eocene. During this time, peculiar monospecific accumulations called nummulite banks (Arni, 1965) developed. The paleoenvironmental interpretation of these banks is still debated. So far, several studies deal with nummulite banks but their quantitative aspects were neglected. Here we present new quantitative observations useful to better define the nummulite bank concept. Samples were collected from Pederiva di Grancona (N. lyelli bank) and San Germano dei Berici (N. fabianii bank; both in the Berici Mts., northern Italy). According to the Shallow Benthic Zonation of Serra Kiel et al. (1998) the Pederiva bank is referred to the SBZ 17 (Early Bartonian), and the San Germano bank to the SBZ 19 (Early Priabonian). In both cases there is a bimodal grain size distribution of microspheres and megalospheres of Nummulites in a fine-grained matrix, giving rise to a packstone texture. In Pederiva, 1448 Nummulites isolated specimens (A-forms) were counted and identified at the species level. Among them 1082 individuals are Nummulites lyelli, so 74.7% of the identified assemblage. Nummulites striatus is the second most-abundant species with the 11.5%, and the rest are the three accessory species N. discorbinus, N. biarritzensis, N. beaumonti. In the San Germano bank, 2043 isolated A-forms of Nummulites were counted and identified at the species level. Among them, 1742 are Nummulites fabianii, which means 85.3% of the assemblage. The second most-abundant species is Nummulites stellatus, accounting for 10.6% of the assemblage. The rest of the assemblage is made by small, lenticular Nummulites (N. incrassatus, N. chavannesi, N. cunialensis and N. garnieri). On polished surfaces of two samples from San Germano and Pederiva, two areas (38 and 76 cm2 respectively) were observed to count all the visible specimens of Nummulites in order to calculate the A/B ratio. The "normal" A/B ratio usually

[Haemophilus influenzae type b in Italy--after thirty years of vaccination may we lower our guard?].

PubMed

Terracciano, Elisa; Zaratti, Laura; Franco, Elisabetta

2015-01-01

Haemophilus influenzae b (Hib) is responsible for meningitis, systemic infections and acute respiratory illness, especially in children. The use of the conjugate vaccines against Hib reduced the incidence of the disease worldwide. In Italy, after the decrease resulted from vaccination, the disease may reappear due to the reduction in vaccination coverage, the presence of infections in adults and vaccine failures.

Wolf-cattle interactions in the northern Rocky Mountains

USDA-ARS?s Scientific Manuscript database

Since gray wolf reintroduction in 1995, wolf populations in the northern Rocky Mountains have increased dramatically. Incidents of wolf predation on livestock have increased with wolf populations. Although rough tallies of livestock death or injury losses caused by wolf predation are made each yea...

Mesothelioma incidence surveillance systems and claims for workers' compensation. Epidemiological evidence and prospects for an integrated framework.

PubMed

Marinaccio, Alessandro; Scarselli, Alberto; Merler, Enzo; Iavicoli, Sergio

2012-07-05

Malignant mesothelioma is an aggressive and lethal tumour strongly associated with exposure to asbestos (mainly occupational). In Italy a large proportion of workers are protected from occupational diseases by public insurance and an epidemiological surveillance system for incident mesothelioma cases. We set up an individual linkage between the Italian national mesothelioma register (ReNaM) and the Italian workers' compensation authority (INAIL) archives. Logistic regression models were used to identify and test explanatory variables. We extracted 3270 mesothelioma cases with occupational origins from the ReNaM, matching them with 1625 subjects in INAIL (49.7%); 91.2% (1,482) of the claims received compensation. The risk of not seeking compensation is significantly higher for women and the elderly. Claims have increased significantly in recent years and there is a clear geographical gradient (northern and more developed regions having higher claims rates). The highest rates of compensation claims were after work known to involve asbestos. Our data illustrate the importance of documentation and dissemination of all asbestos exposure modalities. Strategies focused on structural and systematic interaction between epidemiological surveillance and insurance systems are needed.

Mesothelioma incidence surveillance systems and claims for workers’ compensation. Epidemiological evidence and prospects for an integrated framework

PubMed Central

2012-01-01

Background Malignant mesothelioma is an aggressive and lethal tumour strongly associated with exposure to asbestos (mainly occupational). In Italy a large proportion of workers are protected from occupational diseases by public insurance and an epidemiological surveillance system for incident mesothelioma cases. Methods We set up an individual linkage between the Italian national mesothelioma register (ReNaM) and the Italian workers’ compensation authority (INAIL) archives. Logistic regression models were used to identify and test explanatory variables. Results We extracted 3270 mesothelioma cases with occupational origins from the ReNaM, matching them with 1625 subjects in INAIL (49.7%); 91.2% (1,482) of the claims received compensation. The risk of not seeking compensation is significantly higher for women and the elderly. Claims have increased significantly in recent years and there is a clear geographical gradient (northern and more developed regions having higher claims rates). The highest rates of compensation claims were after work known to involve asbestos. Conclusions Our data illustrate the importance of documentation and dissemination of all asbestos exposure modalities. Strategies focused on structural and systematic interaction between epidemiological surveillance and insurance systems are needed. PMID:22545679

A Seismic Source Model for Central Europe and Italy

NASA Astrophysics Data System (ADS)

Nyst, M.; Williams, C.; Onur, T.

2006-12-01

We present a seismic source model for Central Europe (Belgium, Germany, Switzerland, and Austria) and Italy, as part of an overall seismic risk and loss modeling project for this region. A separate presentation at this conference discusses the probabilistic seismic hazard and risk assessment (Williams et al., 2006). Where available we adopt regional consensus models and adjusts these to fit our format, otherwise we develop our own model. Our seismic source model covers the whole region under consideration and consists of the following components: 1. A subduction zone environment in Calabria, SE Italy, with interface events between the Eurasian and African plates and intraslab events within the subducting slab. The subduction zone interface is parameterized as a set of dipping area sources that follow the geometry of the surface of the subducting plate, whereas intraslab events are modeled as plane sources at depth; 2. The main normal faults in the upper crust along the Apennines mountain range, in Calabria and Central Italy. Dipping faults and (sub-) vertical faults are parameterized as dipping plane and line sources, respectively; 3. The Upper and Lower Rhine Graben regime that runs from northern Italy into eastern Belgium, parameterized as a combination of dipping plane and line sources, and finally 4. Background seismicity, parameterized as area sources. The fault model is based on slip rates using characteristic recurrence. The modeling of background and subduction zone seismicity is based on a compilation of several national and regional historic seismic catalogs using a Gutenberg-Richter recurrence model. Merging the catalogs encompasses the deletion of double, fake and very old events and the application of a declustering algorithm (Reasenberg, 2000). The resulting catalog contains a little over 6000 events, has an average b-value of -0.9, is complete for moment magnitudes 4.5 and larger, and is used to compute a gridded a-value model (smoothed historical

On a report that the 2012 M 6.0 earthquake in Italy was predicted after seeing an unusual cloud formation

USGS Publications Warehouse

Thomas, J.N.; Masci, F; Love, Jeffrey J.

2015-01-01

Several recently published reports have suggested that semi-stationary linear-cloud formations might be causally precursory to earthquakes. We examine the report of Guangmeng and Jie (2013), who claim to have predicted the 2012 M 6.0 earthquake in the Po Valley of northern Italy after seeing a satellite photograph (a digital image) showing a linear-cloud formation over the eastern Apennine Mountains of central Italy. From inspection of 4 years of satellite images we find numerous examples of linear-cloud formations over Italy. A simple test shows no obvious statistical relationship between the occurrence of these cloud formations and earthquakes that occurred in and around Italy. All of the linear-cloud formations we have identified in satellite images, including that which Guangmeng and Jie (2013) claim to have used to predict the 2012 earthquake, appear to be orographic – formed by the interaction of moisture-laden wind flowing over mountains. Guangmeng and Jie (2013) have not clearly stated how linear-cloud formations can be used to predict the size, location, and time of an earthquake, and they have not published an account of all of their predictions (including any unsuccessful predictions). We are skeptical of the validity of the claim by Guangmeng and Jie (2013) that they have managed to predict any earthquakes.

Sex-specific stroke incidence over time in the Greater Cincinnati/Northern Kentucky Stroke Study.

PubMed

Madsen, Tracy E; Khoury, Jane; Alwell, Kathleen; Moomaw, Charles J; Rademacher, Eric; Flaherty, Matthew L; Woo, Daniel; Mackey, Jason; De Los Rios La Rosa, Felipe; Martini, Sharyl; Ferioli, Simona; Adeoye, Opeolu; Khatri, Pooja; Broderick, Joseph P; Kissela, Brett M; Kleindorfer, Dawn

2017-09-05

Recent data suggest stroke incidence is decreasing over time, but it is unknown whether incidence is decreasing in women and men to the same extent. Within our population of 1.3 million, all incident strokes among residents ≥20 years old were ascertained at all hospitals during July 1993-June 1994 and calendar years 1999, 2005, and 2010. A sampling scheme was used to ascertain out-of-hospital cases. Sex-specific incidence rates per 100,000 among black and white participants, age- and race-adjusted, were standardized to the 2000 US Census population. Trends over time by sex were compared; a Bonferroni correction was applied for multiple comparisons. Over the 4 study periods, there were 7,710 incident strokes; 57.2% (n = 4,412) were women. Women were older than men (mean ± SE 72.4 ± 0.34 vs 68.2 ± 0.32, p < 0.001). Incidence of all strokes decreased over time in men (263 [confidence interval 246-281] to 192 [179-205], p < 0.001) but not in women (217 [205-230] to 198 [187-210], p = 0.15). Similar sex differences were seen for ischemic stroke (men, 238 [223-257] to 165 [153-177], p < 0.01; women, 193 [181-205] to 173 [162-184], p = 0.09). Incidence of all strokes and of ischemic strokes was similar between women and men in 2010. Incidence of intracerebral hemorrhage and subarachnoid hemorrhage were stable over time in both sexes. Decreases in stroke incidence over time are driven by a decrease in ischemic stroke in men. Contrary to previous study periods, stroke incidence rates were similar by sex in 2010. Future research is needed to understand why the decrease in ischemic stroke incidence is more pronounced in men. © 2017 American Academy of Neurology.

Seasonal trends and environmental controls of methane emissions in a rice paddy field in Northern Italy

NASA Astrophysics Data System (ADS)

Meijide, A.; Manca, G.; Goded, I.; Magliulo, V.; di Tommasi, P.; Seufert, G.; Cescatti, A.

2011-09-01

Rice paddy fields are one of the greatest anthropogenic sources of methane (CH4), the third most important greenhouse gas after water vapour and carbon dioxide. In agricultural fields, CH4 is usually measured with the closed chamber technique, resulting in discontinuous series of measurements performed over a limited area, that generally do not provide sufficient information on the short-term variation of the fluxes. On the contrary, aerodynamic techniques have been rarely applied for the measurement of CH4 fluxes in rice paddy fields. The eddy covariance (EC) technique provides integrated continuous measurements over a large area and may increase our understanding of the underlying processes and diurnal and seasonal pattern of CH4 emissions in this ecosystem. For this purpose a Fast Methane Analyzer (Los Gatos Research Ltd.) was installed in an eddy-covariance field set-up in a rice paddy field in the Po Valley (Northern Italy). Methane fluxes were measured during the rice growing season, both with EC and with manually operated closed chambers. Methane fluxes were strongly influenced by the presence of the water table, with emissions peaking when it was above 10-12 cm. Further studies are required to evaluate if water table management could decrease CH4 emissions. The development of rice plants and soil temperature were also responsible of the seasonal variation on the fluxes. The EC measured showed a diurnal cycle in the emissions, which was more relevant during the vegetative period, and with CH4 emissions being higher in the late evening, possibly associated with higher water temperature. The comparison between both measurement techniques shows that greater fluxes are measured with the chambers, especially when higher fluxes are being produced, resulting in 30 % higher seasonal estimations with the chambers than with the EC (41.1 and 31.8 g CH4 m-2 measured with chambers and EC respectively). The differences may be a result of the combined effect of

Socioeconomic patterning in the incidence and survival of teenage and young adult men aged between 15 and 24 years diagnosed with non-seminoma testicular cancer in northern england.

PubMed

McNally, Richard J Q; Basta, Nermine O; Errington, Steven; James, Peter W; Norman, Paul D; Hale, Juliet P; Pearce, Mark S

2015-12-01

Previous research from developed countries has shown a marked increase in the incidence of testicular cancer in the past 50 years. This has also been demonstrated in northern England, along with improving 5-year survival. The present study aims to determine if socioeconomic factors may play a role in both etiology and survival from non-seminoma testicular cancer. We extracted all 214 cases of non-seminoma testicular cancer diagnosed in teenage and young adult men aged between 15 and 24 years during 1968 to 2006 from the Northern Region Young Persons' Malignant Disease Registry, which is a population-based specialist regional registry. Negative binomial regression was used to examine the relationship between incidence and both the Townsend deprivation score (and component variables) and small-area population density. Cox regression was used to analyze the relationship between survival and both deprivation and population density. Decreased incidence was associated with living in areas of higher household overcrowding for young adults aged between 20 and 24 years (relative risk per 1% increase in household overcrowding = 0.79; 95% CI: 0.66-0.94) but no association was detected for young people aged between 15 and 19 years. Community-level household unemployment was associated with worse survival (hazard ratio per 1% increase in household unemployment = 1.04; 95% CI: 1.00-1.08). This study has shown that increased risk of non-seminoma testicular cancer in teenage and young adult men may be associated with some aspect of more advantaged living. In contrast, greater deprivation is linked with worse survival prospects. The study was ecological by design and so these area-based results may not necessarily apply to individuals. Copyright © 2015 Elsevier Inc. All rights reserved.

Epidemiological survey of X-linked bulbar and spinal muscular atrophy, or Kennedy disease, in the province of Reggio Emilia, Italy.

PubMed

Guidetti, D; Sabadini, R; Ferlini, A; Torrente, I

2001-01-01

Commencing with the work carried out during the epidemiological survey of amyotrophic lateral sclerosis in the period 1980-1992 and the pathology follow-up, we carried out a perspective incidence, prevalence and mortality survey of X-linked bulbar and spinal muscular atrophy (X-BSMA) in the province of Reggio Emilia in Northern Italy. Based on 11 patients (eight familial and three sporadic cases), the mean incidence per year for the period 1980 through 1997, as evaluated at the onset of symptoms, was 0.09 cases/100,000 for the total population and 0.19 cases/100,000 for the male population. On December 31, 1997, the prevalence rate was 1.6/100,000 for the total population and 3.3/100,000 for the male population. In the 18-year period of 1980-1997, the average yearly mortality rate was: 0.03 cases/100,000 per year for the total population and 0.06 cases/ 100,000 for the male population. The average age at onset was 44.8 +/- 10.1, and the average survival period was 27.3 +/- 2.3 years. The average age of the prevalence day was 58.9 +/- 14.9, and the average age at death was 71.3 +/- 4.7 years. Whereas the incidence rate of X-BSMA in the province of Reggio Emilia is 16 times lower that of amyotrophic lateral sclerosis (ALS), the incidence rate of progressive bulbar palsy in the male population is only slightly higher than X-BSMA; and the prevalence rate of ALS for males is two times the prevalence rate for X-BSMA, with overlapping of confidence intervals. X-BSMA is a rare disease, which is probably under-diagnosed, but due to the long survival period of this disease its frequency is not negligible. Because of the presence of sporadic cases or non-evident familial cases, it is appropriate to consider this diagnostic possibility in making a diagnosis of ALS in patients in whom lower motor neuron dysfunction or bulbar onset predominates.

Risk of hematological malignancies associated with magnetic fields exposure from power lines: a case-control study in two municipalities of northern Italy.

PubMed

Malagoli, Carlotta; Fabbi, Sara; Teggi, Sergio; Calzari, Mariagiulia; Poli, Maurizio; Ballotti, Elena; Notari, Barbara; Bruni, Maurizio; Palazzi, Giovanni; Paolucci, Paolo; Vinceti, Marco

2010-03-30

Some epidemiologic studies have suggested an association between electromagnetic field exposure induced by high voltage power lines and childhood leukemia, but null results have also been yielded and the possibility of bias due to unmeasured confounders has been suggested. We studied this relation in the Modena and Reggio Emilia municipalities of northern Italy, identifying the corridors along high voltage power lines with calculated magnetic field intensity in the 0.1-<0.2, 0.2-<0.4, and > or = 0.4 microTesla ranges. We identified 64 cases of newly-diagnosed hematological malignancies in children aged <14 within these municipalities from 1986 to 2007, and we sampled four matched controls for each case, collecting information on historical residence and parental socioeconomic status of these subjects. Relative risk of leukemia associated with antecedent residence in the area with exposure > or = 0.1 microTesla was 3.2 (6.7 adjusting for socioeconomic status), but this estimate was statistically very unstable, its 95% confidence interval being 0.4-23.4, and no indication of a dose-response relation emerged. Relative risk for acute lymphoblastic leukemia was 5.3 (95% confidence interval 0.7-43.5), while there was no increased risk for the other hematological malignancies. Though the number of exposed children in this study was too low to allow firm conclusions, results were more suggestive of an excess risk of leukemia among exposed children than of a null relation.

Risk of hematological malignancies associated with magnetic fields exposure from power lines: a case-control study in two municipalities of northern Italy

PubMed Central

2010-01-01

Background Some epidemiologic studies have suggested an association between electromagnetic field exposure induced by high voltage power lines and childhood leukemia, but null results have also been yielded and the possibility of bias due to unmeasured confounders has been suggested. Methods We studied this relation in the Modena and Reggio Emilia municipalities of northern Italy, identifying the corridors along high voltage power lines with calculated magnetic field intensity in the 0.1-<0.2, 0.2-<0.4, and ≥ 0.4 microTesla ranges. We identified 64 cases of newly-diagnosed hematological malignancies in children aged <14 within these municipalities from 1986 to 2007, and we sampled four matched controls for each case, collecting information on historical residence and parental socioeconomic status of these subjects. Results Relative risk of leukemia associated with antecedent residence in the area with exposure ≥ 0.1 microTesla was 3.2 (6.7 adjusting for socioeconomic status), but this estimate was statistically very unstable, its 95% confidence interval being 0.4-23.4, and no indication of a dose-response relation emerged. Relative risk for acute lymphoblastic leukemia was 5.3 (95% confidence interval 0.7-43.5), while there was no increased risk for the other hematological malignancies. Conclusions Though the number of exposed children in this study was too low to allow firm conclusions, results were more suggestive of an excess risk of leukemia among exposed children than of a null relation. PMID:20353586

The Cost of Arbovirus Disease Prevention in Europe: Area-Wide Integrated Control of Tiger Mosquito, Aedes albopictus, in Emilia-Romagna, Northern Italy

PubMed Central

Canali, Massimo; Rivas-Morales, Stefano; Beutels, Philippe; Venturelli, Claudio

2017-01-01

Aedes albopictus (tiger mosquito) has become the most invasive mosquito species worldwide, in addition to being a well-known vector of diseases, with a proven capacity for the transmission of chikungunya and dengue viruses in Europe as well as the Zika virus in Africa and in laboratory settings. This research quantifies the cost that needs to be provided by public-health systems for area-wide prevention of arboviruses in Europe. This cost has been calculated by evaluating the expenditure of the plan for Aedes albopictus control set up in the Emilia-Romagna region (Northern Italy) after a chikungunya outbreak occurred in 2007. This plan involves more than 280 municipalities with a total of 4.2 million inhabitants. Public expenditure for plan implementation in 2008–2011 was examined through simple descriptive statistics. Annual expenditure was calculated to be approximately €1.3 per inhabitant, with a declining trend (from a total of €7.6 million to €5.3 million) and a significant variability at the municipality level. The preventative measures in the plan included antilarval treatments (about 75% of total expenditure), education for citizens and in schools, entomological surveillance, and emergency actions for suspected viremias. Ecological factors and the relevance of tourism showed a correlation with the territorial variability in expenditure. The median cost of one antilarval treatment in public areas was approximately €0.12 per inhabitant. Organizational aspects were also analyzed to identify possible improvements in resource use. PMID:28425959

Ongoing outbreak with well over 4,000 measles cases in Italy from January to end August 2017 - what is making elimination so difficult?

PubMed

Filia, Antonietta; Bella, Antonino; Del Manso, Martina; Baggieri, Melissa; Magurano, Fabio; Rota, Maria Cristina

2017-09-14

We report an ongoing measles outbreak in Italy, with over 4,400 cases reported in 20 Regions from January to August 2017. Median age was 27 years, 88% of the cases were unvaccinated. The highest incidence was in infants below one year of age and 7% of cases occurred among healthcare workers. Three deaths occurred and two cases of encephalitis were reported. Wide immunity gaps and nosocomial transmission are major challenges to measles elimination in Italy. This article is copyright of The Authors, 2017.

Severe Mental Retardation in Children in a Northern Swedish County

ERIC Educational Resources Information Center

And Others; Gustavson, K. H.

1977-01-01

Presented are results of a study of the incidence, prevalence, gestational age, birth weight, associated central nervous system disorders, and etiological and pathogenetic aspects of 161 severely mentally retarded children in Northern Sweden. (CL)

Trends in incidence of breast cancer among women under 40 in seven European countries: a GRELL cooperative study.

PubMed

Leclère, Brice; Molinié, Florence; Trétarre, Brigitte; Stracci, Fabrizio; Daubisse-Marliac, Laetitia; Colonna, Marc

2013-10-01

Young women are not usually screened for breast cancer (BC). The trends in incidence in this population may better reflect changes in risk factors. However, studies on this subject are scarce and heterogeneous. The aim of this study was to describe the trends in incidence of BC in women under 40 from 1990 to 2008, using pooled European data. Thirty-seven European population-based cancer registries from Belgium, Bulgaria, France, Italy, Portugal, Spain and Switzerland participated in this study. World age-standardized incidence rates were first analyzed graphically and then using a Poisson regression model, in order to estimate average annual percent changes (AAPCs). The overall incidence rate of BC in the area covered increased linearly during the study period by 1.19% (0.93; 1.46) on average per year. This increase varied between countries from 0.20% (-0.53; 0.64) in Bulgaria to 2.68% (1.97; 3.40) in Portugal. In Italy, after a significant rise of 2.33% (1.14; 3.54) per year, BC incidence began decreasing in 2002 by -2.30% (-4.07; -0.50) yearly. The rise in incidence was greater for women under 35 and for ductal carcinomas. This increase can be due to a rise in risk factors and/or changes in diagnosis and surveillance practices, but we could not clearly distinguish between these two non-exclusive explanations. Copyright © 2013 Elsevier Ltd. All rights reserved.

Using an integrated approach to the assessment of the psychosocial work environment: the case of a major hospital in northern Italy.

PubMed

Lanfranchi, Fiorella; Alaimo, Sara; Conway, P M

2014-01-01

In 2010, Italian regulatory guidelines have been issued consisting of a stepwise procedure for the assessment and management of work-related stress. However, research that empirically examines whether this procedure proves effective in accurately identifying critical psychosocial factors and informing risk management is scarce. To examine the differential sensitivity of two approaches to risk assessment, the first based on objective instruments only, the second consisting of an integrated approach combining different methods and theoretical perspectives. We examined a sample of 306 healthcare employees in a large-size hospital in northern Italy, using a series of tools, both quantitative (an observational checklist and the HSE-IT and MOHQ questionnaires) and qualitative (Focus Groups). Through instrument-specific reference values, we then compared risk profiles between different homogeneous groups within the institution. The psychosocial work environment resulted to be far more positive when adopting the first compared to the second approach to risk assessment. The latter approach was also more sensitive in detecting between-groups differences in risk profiles. Furthermore, the Focus Groups returned a more context-specific picture of the psychosocial work environment. Finally, going beyond the emphasis on negative working conditions inherent in the other quantitative instruments, the MOHQ allowed for also identifying health-promoting factors in need for improvement. Although more research is needed to confirm our findings, the present study suggests that using an integrated approach to assess the psychosocial work environment may be the most effective way to accurately identify risk factors and support the management process.

2015-2018 Regional Prevention Plan of Lombardy (Northern Italy) and sedentary prevention: a cross-sectional strategy to develop evidence-based programmes.

PubMed

Coppola, Liliana; Ripamonti, Ennio; Cereda, Danilo; Gelmi, Giusi; Pirrone, Lucia; Rebecchi, Andrea

2016-01-01

Cross-sector, life-course, and setting approaches are identified in the 2015-2018 Regional Prevention Plan (PRP) of Lombardy Region (Northern Italy) as valuable strategies to ensure the efficacy and sustainable prevention of the non-communicable disease (NCDs). The involvement of non-health sectors in health promotion activities represents a suitable strategy to affect on social, economic, and political determinants and to change environmental factors that could cause NCDs. A dialogue among communities, urban planning, and prevention know-how is a prerequisite to develop a system of policies suitable to promote healthy lifestyle in general and, specifically, active lifestyles. The 2015-2018 Lombardy PRP pursues its aims of health promotion and behavioural risk factors for NCDs prevention through programmes that implement their own setting networks (Health Promoting Schools - SPS; Workplace Health Promotion - WHP) and develop new networks. Sedentary lifestyle prevention and active lifestyle promotion are performed through the approach promoted by the Healthy Cities Programme (WHO), encouraging two main processes: 1. creating integrated capacity-building among health and social prevention services, academic research, and local stakeholders on different urban planning and design issues; 2. promoting community empowerment through active citizens participation. Through this process, Lombardy Region aims to orient its services developing evidence-based programmes and enhancing advocacy and mediating capacity skills in order to create a profitable partnership with non-health sectors. This paper reports the main impact data: 26,000 children that reach school by foot thanks to walking buses, 57% of 145 companies joining WHP are involved in promoting physical activity, 18,891 citizens who attend local walking groups.

Age and speleogenesis of epigenic gypsum caves in the northern Apennines (Italy)

NASA Astrophysics Data System (ADS)

Columbu, Andrea; Chiarini, Veronica; De Waele, Jo; Drysdale, Russell; Forti, Paolo; Hellstrom, John; Woodhead, Jon

2016-04-01

Triassic and Messinian gypsum beds host the majority of the caves in the eastern flank of the northern Apennines. To date, more than six hundreds voids have been mapped, including the longest known epigenic gypsum cave system in the world (Spipola-Acquafredda, ~11 km of tunnels) (De Waele et al., 2013). Superimposed caves are typically sub-horizontal (Klimchouk, 2000) and connected through vertical shafts, reflecting the palaeo base-level variations. When preserved, river terraces at the surface lie at the same palaeo altitude of the base level and horizontal cave passages. Notwithstanding the well-known geology of the area known (Vai and Martini, 2001), the age of these caves has been greatly underestimated in the past. Considering the rapid dissolution of the gypsum and uplifting of the area, the start of speleogenesis activity was considered to have occurred during the last glacial age. The age of karst voids can be only indirectly estimated by the dating of the infilling sediments. U-Th dating on carbonate speleothems provides high-precision and accurate ages (Hellstrom, 2003; Scholz and Hoffmann, 2008). We thus applied this methodology to 20 speleothems coming from 14 different caves belonging to the Monte Tondo, Spipola Acquafredda, Castelnuovo, Stella-Rio Basino and Brisighella systems. The results show that: i) caves were forming since at least ~300 ka; ii) the peak of speleogenesis was reached during relatively cold climate stages, when rivers formed terraces at the surface and aggradation caused paragenesis in the stable cave levels (Columbu et al., 2015). Besides the significant contribution to the understanding of the Apennines evaporite karst evolution, this study (and its further advancement) may also refine knowledge of the local vs regional uplifting rates and base-level variations since the late Pleistocene (Wegmann and Pazzaglia, 2009). References Columbu, A., De Waele, J., Forti, P., Montagna, P., Picotti, V., Pons-Branchu, E., Hellstrom, J

Prevalence of Staphylococcus aureus and of methicillin-resistant S. aureus clonal complexes in bulk tank milk from dairy cattle herds in Lombardy Region (Northern Italy).

PubMed

Cortimiglia, C; Luini, M; Bianchini, V; Marzagalli, L; Vezzoli, F; Avisani, D; Bertoletti, M; Ianzano, A; Franco, A; Battisti, A

2016-10-01

Staphylococcus aureus is the most important causative agent of subclinical mastitis in cattle resulting in reduced milk production and quality. Methicillin-resistant S. aureus (MRSA) strains has a clear zoonotic relevance, especially in the case of occupational exposure. The aim of the study was to evaluate the prevalence of S. aureus and MRSA in bulk tank milk (BTM) from dairy cattle herds in the Lombardy Region (Northern Italy) and to identify the main MRSA circulating genotypes. MRSA strains were characterized by susceptibility testing, multi-locus sequence typing (MLST), spa typing and SCCmec typing. A total 844 BTM samples were analysed and S. aureus and MRSA were detected in 47·2% and 3·8% of dairy herds, respectively. MLST showed that the majority (28/32) of isolates belonged to the typical livestock-associated lineages: ST398, ST97 and ST1. Interestingly, in this study we report for the first time the new ST3211, a single locus variant of ST(CC)22, with the newly described 462 aroE allele. Our study indicates high diffusion of S. aureus mastitis and low, but not negligible, prevalence of MRSA in the considered area, suggesting the need for planning specific control programmes for bovine mastitis caused by S. aureus, especially when MRSA is implicated.

[Perceived discrimination at work for being an immigrant: a study on self-perceived mental health status among immigrants in Italy].

PubMed

Di Napoli, Anteo; Gatta, Rosaria; Rossi, Alessandra; Perez, Monica; Costanzo, Gianfranco; Mirisola, Concetta; Petrelli, Alessio

2017-01-01

exposure to discrimination is widely understood as a social determinant of psychophysical health and a contributing factor to health inequities among social groups. Few studies exist, particularly in Italy, about the effects of discrimination among immigrants at workplace. to analyse the association between perceived discrimination at work for being an immigrant and mental health status among immigrants in Italy. a sub-sample of 12,408 immigrants residing in Italy was analysed. data came from the survey "Social conditions and integration of foreign citizens in Italy", carried out in 2011-2012 by the Italian National Institute of Statistics (Istat). Self-perceived mental health status was measured through mental component summary (MCS) of SF-12 questionnaire, assuming as worse health status MCS score distribution ≤1st quartile. In order to evaluate the probability of poor health status, a multivariate log-binomial model was performed assuming: discrimination at work for being an immigrant as determinant variable; age, gender, educational level, employment status, area of origin, residence in Italy, length of stay in Italy, self-perceived loneliness and satisfaction about life as potential confounding variables. among immigrants, 15.8% referred discrimination at his/her workplace in Italy for being an immigrant. Higher probability of poor mental health status was observed for immigrants who referred discrimination at workplace (Prevalence Rate Ratio - PRR: 1.16) who arrived in Italy since at least 5 years (PRR: 1.14), for not employed subjects (PRR: 1.31), and for people from the Americas (PRR: 1.14). Lower probability of poor mental health status was found in immigrants from Western- Central Asia (PRR: 0.83) and Eastern-Pacific Asia (PRR: 0.79). Compared to immigrants residing in North-Eastern Italy, higher probability of worse mental health status was observed in people who resided in Northern-Western (PRR: 1.30), Central (PRR: 1.26), and Southern (PRR: 1

Epidemiology of cholelithiasis in southern Italy. Part II: Risk factors.

PubMed

Misciagna, G; Leoci, C; Guerra, V; Chiloiro, M; Elba, S; Petruzzi, J; Mossa, A; Noviello, M R; Coviello, A; Minutolo, M C; Mangini, V; Messa, C; Cavallini, A; De Michele, G; Giorgio, I

1996-06-01

To determine behavioural, dietary and other common factors associated with new cases of gallstones, diagnosed by ultrasonography, in a prospective cohort study conducted in southern Italy. Between May 1985 and June 1986, systematic sampling from the electoral register of Castellana, a small town in southern Italy, yielded 2472 subjects who had had their gallbladder checked for gallstones by ultrasonography. Between May 1992 and June 1993, 1962 out of the 2235 (87.7%) subjects without gallstones at baseline agreed to a further ultrasound examination. At the first survey a standardized questionnaire was administered, inquiring about medical history, diet, cigarette smoking and other behavioural characteristics. Height and weight were also measured, and blood levels of glucose, cholesterol, HDL-cholesterol and triglycerides were determined by standard methods. The same variables were measured at the second survey. The diagnosis of gallstones was made with the same echograph by echographists working in the same department. Multiple logistic regression was used to determine which factors measured at the first survey were associated with the incident cases of gallstones. One hundred and four subjects had developed gallstones, an incidence of 9.7 per 1000 persons per year. Age, body mass index (BMI), weight change, a history of diabetes, constipation (shown by use of laxatives), cigarette smoking, years of schooling, consumption of fried foods and excessive oil, and pregnancy in females, were positively associated with the incidence of gallstones. Consumption of wine, coffee, fish and wholemeal bread was inversely associated. Sex, family history of cholelithiasis, use of oral contraceptives and serum lipids were not independent risk factors for gallstones. The results of this study confirm many gallstone-associated factors reported in previous cross-sectional and case-control studies, as well as in other cohort studies based on the clinical diagnosis of gallstones, such

Population density and distribution of wheat bugs infesting durum wheat in Sardinia, Italy.

PubMed

Salis, Luigi; Goula, Marta; Izquierdo, Jordi; Gordún, Elena

2013-01-01

Wheat is a very important crop in Italy, and is infested by wheat bugs belonging to the genera Eurygaster (Hemiptera: Scutellaridae) and Aelia (Hemiptera: Pentatomidae). Many wheat bug infestations have been reported in the north, south, and center of Italy, both in the past as well as recently. The present study was carried out in Sardinia, Italy, during two years (2007 and 2008). The objective of this study was to determine the species and distribution of wheat bugs in durum wheat fields in Sardinia, and to estimate their population density in order to know the incidence of the pest on the island. Sampling took place twice a year (May and June) in three zones, representative of durum wheat cropping in the island. Four species of wheat bugs were found; the predominant species was Eurygaster austriaca (Schrank), followed by Aelia germari (Kuster), Eurygaster maura L., and Aelia acuminata L. The average density of wheat bugs was low (1.1 individuals/m²), but in certain areas it was above the damage threshold (4 individuals/m²). For this reason, the conclusion of the study is that this pest should be monitored in order to control outbreaks and prevent their further spread.

Population Density and Distribution of Wheat Bugs Infesting Durum Wheat in Sardinia, Italy

PubMed Central

Salis, Luigi; Goula, Marta; Izquierdo, Jordi; Gordún, Elena

2013-01-01

Wheat is a very important crop in Italy, and is infested by wheat bugs belonging to the genera Eurygaster (Hemiptera: Scutellaridae) and Aelia (Hemiptera: Pentatomidae). Many wheat bug infestations have been reported in the north, south, and center of Italy, both in the past as well as recently. The present study was carried out in Sardinia, Italy, during two years (2007 and 2008). The objective of this study was to determine the species and distribution of wheat bugs in durum wheat fields in Sardinia, and to estimate their population density in order to know the incidence of the pest on the island. Sampling took place twice a year (May and June) in three zones, representative of durum wheat cropping in the island. Four species of wheat bugs were found; the predominant species was Eurygaster austriaca (Schrank), followed by Aelia germari (Kuster), Eurygaster maura L., and Aelia acuminata L. The average density of wheat bugs was low (1.1 individuals/m2), but in certain areas it was above the damage threshold (4 individuals/m2). For this reason, the conclusion of the study is that this pest should be monitored in order to control outbreaks and prevent their further spread. PMID:23906035

Prevalence of Paget's disease of bone in Italy.

PubMed

Gennari, Luigi; Di Stefano, Marco; Merlotti, Daniela; Giordano, Nicola; Martini, Giuseppe; Tamone, Cristina; Zatteri, Roberto; De Lucchi, Roberto; Baldi, Carlo; Vattimo, Angelo; Capoccia, Silvia; Burroni, Luca; Geraci, Simone; De Paola, Vincenzo; Calabrò, Anna; Avanzati, Annalisa; Isaia, Giancarlo; Nuti, Ranuccio

2005-10-01

We examined the prevalence of PDB in Italy from radiological, scintigraphic, and biochemical surveys in two Italian towns. Prevalence rates varied from 0.7% to 2.4%, were higher in males than in females, and slightly differed between the two towns. Unlike previous studies in populations of British descent, no secular trend for a decreasing prevalence emerged. Clinical, radiological, and necropsy data from different countries suggested pronounced geographical variations in the prevalence of Paget's disease of bone (PDB). Despite the impact of the disease on the population, there are limited data on the prevalence of PDB in Italy. The objective of this study was to estimate the prevalence of PDB in the district of Siena (Central Italy) and Turin (Northern Italy) from radiological, biochemical, and scintigraphic surveys. We examined a sample of 1778 consecutive pelvic radiographs performed between 1999 and 2000 at the Hospital Radiology Unit in Siena and 6609 pelvic radiographs performed in 1986-1987, 1992-1993, and 1999-2002 from the Radiology Department of Molinette Hospital in Turin. In Siena, 7906 consecutive (99m)TC-MDP bone scans performed over a 4-year period (January 2000 to May 2004) were also screened for the presence of PDB, and the prevalence of elevated alkaline phosphatase (ALP) levels (>300 UI/liter) was estimated from 7449 computerized medical records over a 3-year period (January 2000 to February 2003). The finding of PDB on the pelvic radiograph and bone scan was based on standardized radiological criteria. At the end of the radiological surveys, 16/1778 pelvic PDB cases (8 males and 8 females) were observed in Siena and 41/6609 (27 males and 14 females) in Turin. The crude prevalence of the disease was 0.89% in Siena and 0.62% in Turin. Given that pelvic involvement is commonly described in 60-90% of PDB patients, the estimated overall prevalence of PDB ranged from 1.0% to 1.5% in Siena and from 0.7% to 1.0% in Turin. No decrease in the prevalence

Epidemiological changes in AIDS and HIV infection in Italy.

PubMed

Suligoi, Barbara; Pezzotti, Patrizio; Boros, Stefano; Urciuoli, Roberta; Rezza, Giovanni

2003-01-01

This article describes the major changes in the human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/ AIDS) epidemic in Italy, using data from the National AIDS Registry and from 5 local surveillance systems for new HIV diagnoses. From 1982 to 2001, 49,063 adults with AIDS were reported to the AIDS Registry. From 1988 to 2000, the 5 local systems reported 23,252 new HIV diagnoses. The AIDS incidence increased until 1995, followed by a progressive decrease. A decrease was also observed for the incidence of new HIV diagnoses after 1989, with an apparent stabilization after 1998. Most AIDS cases have been represented by intravenous drug users (IDU), yet since 1999 the percentage of cases attributable to sexual transmission has exceeded that for IDUs. Similarly, among new HIV diagnoses, the percentage of cases attributable to sexual transmission increased from 23.6% before 1993 to 58.5% in 2000. The percentage of people with AIDS who discovered their seropositivity no earlier than 6 months before AIDS diagnosis increased from 20.6% in 1996 to 48.8% in 2001. Although the incidence of both AIDS and new HIV diagnoses has declined, a possible resurgence of the epidemic cannot be ruled out, in light of various factors that could lead to an increasing number of living infected people.

Molecular Identification of Two Vector Species, Cacopsylla melanoneura and Cacopsylla picta (Hemiptera: Psyllidae), of Apple Proliferation Disease and Further Common Psyllids of Northern Italy.

PubMed

Oettl, Sabine; Schlink, Katja

2015-10-01

The psyllid species Cacopsylla melanoneura (Förster) and Cacopsylla picta (Förster) are vectors of 'Candidatus Phytoplasma mali', the causal agent of apple proliferation, one of the economically most important apple diseases in Europe. Both vectors are present in apple orchards of South Tyrol and Trentino provinces in Northern Italy. As no direct treatment of the disease is possible, monitoring of the psyllids provides information about the vector presence in the orchards and enables targeted control. Thus, fast and reliable identification of the various psyllids occurring in the apple orchards is required. Morphological differentiation is problematic due to extensive resemblance of some psyllid species especially among females and is error-prone for nymphs. Here we present a rapid and cost-effective polymerase chain reaction-restriction fragment length polymorphism method based on the cytochrome c oxidase subunit I region for the molecular identification of the vector species as well as eight further Cacopsylla species present in the orchards. This method was verified through 98.9% consensus with morphologically identified males, through sequencing and subsequent phylogenetic analysis. In case of doubtful morphological identification of females, the method was able to provide a refined species assignment and could also remarkably facilitate the identification of nymphs. © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

Anisakis hypersensitivity in Italy: prevalence and clinical features: a multicenter study.

PubMed

2011-12-01

Anisakis simplex (As), a parasite in fish, is able to sensitize humans via the alimentary tract. The prevalence of hypersensitivity and allergy to As outside the Iberian peninsula has not been investigated so far. We investigated Anisakis hypersensitivity in different areas of Italy. Consecutive subjects seen at 34 Italian allergy centers from October to December 2010 were investigated both by specific interview and by skin prick test (SPT) with As extract. A total of 10 570 subjects were screened, of which 474 (4.5%) scored positive on Anisakis SPT and 66 of these (14% of those sensitized; 0.6% of the studied population) had a history of As allergy. Marinated anchovies were the most frequent cause of allergic reactions. Thirty-four (52%) patients were mono-sensitized to Anisakis. Sensitization rate showed marked geographic differences (range: 0.4-12.7%), being highest along the Adriatic and Tyrrhenian coasts, where homemade marinated anchovies are an age-old tradition. In inland centers in northern Italy, the prevalence was directly related to the number of inhabitants. The analysis of the impact of immigration on the prevalence of Anisakis hypersensitivity showed that about 60% of sensitized subjects in Milano and Torino came from southern Italy or from non-European countries. Anisakis hypersensitivity and allergy are mainly a matter of dietary habits. Areas where marinated anchovies are popular can be considered as 'endemic' for this type of food allergy, whereas immigration and, possibly, new or imported trendy food styles, such as eating raw fish carpaccios or sushi, are a major causative factor in big cities of inland zones. © 2011 John Wiley & Sons A/S.

Towards measles elimination in Italy: Virological surveillance and genotypes trend (2013-2015).

PubMed

Magurano, Fabio; Baggieri, Melissa; Filia, Antonietta; Del Manso, Martina; Lazzarotto, Tiziana; Amendola, Antonella; D'Agaro, Pierlanfranco; Chironna, Maria; Ansaldi, Filippo; Iannazzo, Stefania; Bucci, Paola; Marchi, Antonella; Nicoletti, Loredana

2017-05-15

In accordance with the goal of the World Health Organization Regional Office for Europe, the Italian National Measles and Rubella Elimination Plan aimed to interrupt indigenous measles transmission in Italy by the end of 2015. However, from 2013 to 2015, Italy experienced high measles burden with 4902 measles cases (49.3% laboratory-confirmed) reported to the enhanced measles surveillance system (cumulative incidence in the triennium reference period: 2.4/100,000 population). The measles elimination goal was not reached. Laboratory surveillance of measles circulating genotypes is performed by the Measles and Rubella National Reference Laboratory (NRL) at the Italian National Institute of Health (Istituto Superiore di Sanità - ISS), in Rome. Samples received from 1 January 2013-31 December 2015 were analysed. Those positive for measles genome by molecular tests were sequenced and phylogenetically analysed. Phylogenetic analysis performed by NRL identified that genotypes D4 and D8 were endemic and co-circulated in 2011-2013: study results show that genotype D4 disappeared during 2013. Sporadic cases were associated to genotype B3 during 2011-2013, which became endemic in Italy during 2014 and co-circulated with D8 until 2015. Sporadic cases were found belonging to genotypes D9 and H1 all over the period in exam. Similar trend has been observed in European WHO Region. Copyright © 2017 Elsevier B.V. All rights reserved.

Etiological Survey on Intellectual Disability in the Northern Finland Birth Cohort 1986

ERIC Educational Resources Information Center

Heikura, Ulla; Linna, Sirkka-Liisa; Olsen, Paivi; Hartikainen, Anna-Liisa; Taanila, Anja; Jarvelin, Marjo-Riitta

2005-01-01

The etiology of intellectual disability was studied both in incident (n = 9,432) and prevalent (n = 9,351) populations in a one-year birth cohort born in Northern Finland in 1985-1986. Data from multiple sources were used to follow the children until the age of 11.5 years. Of the incident cases (n = 119) with intellectual disabilities, 66.4% had…

[Hansen's disease in the northern region of Brazil--1986].

PubMed

Britto, R da S

1989-12-01

Some general facts about Hansen's Disease are presented: in the world, in the Americas, in 1986, with the purpose to focalize on the Northern Region of Brazil (Amazon Valley) where an attempt is made to specify, State, the clinical forms in the active registry, the respective coefficients of Prevalence, about the cases detected during the year, by clinical forms and the correspondent Coefficient of Incidence, the age range of less than 15 years, and above 15 years; and to analyze according to the township in the State of Amazonas in a series of 8 years, from 1979 to 1986, the registered cases under control and also without control, the new cases, by clinical form and Coefficient of Incidence, the positive cases among students in the capital and also in the country, and with more details, still by township and by Public Health Registry, in 1986, with the population, new cases, and Coefficient of Incidence, cases of the active registry, cases under control, Coefficient of Incidence, the relationship between patients/inhabitants, cases according to the decreasing intensity as far as the Prevalence and Health Department Regions: all this to give an idea, in detail, inclusive statistics, of the real position of Hansen's Disease in the Northern Region (Amazon Valley), with the highest figures of Prevalence and even of Incidence, in comparison with other Regions of the country, and to stress the grave situation of the endemic proportions of the disease, in Brazil in general and in that Regions, in particular.

Comparison of three methods to derive canopy-scale flux measurements above a mixed oak and hornbeam forest in Northern Italy

NASA Astrophysics Data System (ADS)

Acton, William; Schallhart, Simon; Langford, Ben; Valach, Amy; Rantala, Pekka; Fares, Silvano; Carriero, Giulia; Mentel, Thomas; Tomlinson, Sam; Dragosits, Ulrike; Hewitt, Nicholas; Nemitz, Eiko

2015-04-01

Plants emit a wide range of Biogenic Volatile Organic Compounds (BVOCs) into the atmosphere. These BVOCs are a major source of reactive carbon into the troposphere and play an important role in atmospheric chemistry by, for example, acting as an OH sink and contributing to the formation of secondary organic aerosol. While the emission rates of some of these compounds are relatively well understood, large uncertainties are still associated with the emission estimates of many compounds. Here the fluxes and mixing ratios of BVOCs recorded during June/July 2012 over the Bosco Fontana forest reserve in northern Italy are reported and discussed, together with a comparison of three methods of flux calculation. This work was carried out as a part of the EC FP7 project ECLAIRE (Effects of Climate Change on Air Pollution and Response Strategies for European Ecosystems). The Bosco Fontana reserve is a semi natural deciduous forest dominated by Carpinus betulus (hornbeam), Quercus robur (pedunculate oak) and Quercus rubra (northern red oak). Virtual disjunct eddy covariance measurements made using Proton Transfer Reaction-Mass Spectrometry (PTR-MS) and Proton Transfer Reaction-Time of Flight-Mass Spectrometry (PTR-ToF-MS) were used to calculate fluxes and mixing ratios of BVOCs above the forest canopy at Bosco Fontana. BVOC mixing ratios were dominated by methanol with acetaldehyde, acetone, acetic acid, isoprene, the sum of methyl vinyl ketone and methacrolein, methyl ethyl ketone and monoterpenes also recorded. A large flux of isoprene was observed as well as significant fluxes of monoterpenes, methanol, acetaldehyde and methyl vinyl ketone / methacrolein. The fluxes recorded using the PTR-MS and PTR-ToF-MS showed good agreement. Comparison of the isoprene fluxes calculated using these instruments also agreed well with fluxes modelled using the MEGAN algorithms (Guenther et al. 2006). The detailed tree distribution maps for the forest at Bosco Fontana compiled by Dalponte et

Incidence of plastic fragments among burrow-nesting seabird colonies on offshore islands in northern New Zealand.

PubMed

Buxton, Rachel T; Currey, Caitlin A; Lyver, Philip O'B; Jones, Christopher J

2013-09-15

Marine plastic pollution is ubiquitous throughout the world's oceans, and has been found in high concentrations in oceanic gyres of both the northern and southern hemispheres. The number of studies demonstrating plastic debris at seabird colonies and plastic ingestion by adult seabirds has increased over the past few decades. Despite the recent discovery of a large aggregation of plastic debris in the South Pacific subtropical gyre, the incidence of plastics at seabird colonies in New Zealand is unknown. Between 2011 and 2012 we surveyed six offshore islands on the northeast coast of New Zealand's North Island for burrow-nesting seabird colonies and the presence of plastic fragments. We found non-research related plastic fragments (0.031 pieces/m(2)) on one island only, Ohinau, within dense flesh-footed shearwater (Puffinus carneipes) colonies. On Ohinau, we found a linear relationship between burrow density and plastic density, with 3.5 times more breeding burrows in areas with plastic fragments found. From these data we conclude that plastic ingestion is a potentially a serious issue for flesh-footed shearwaters in New Zealand. Although these results do not rule out plastic ingestion by other species, they suggest the need for further research on the relationship between New Zealand's pelagic seabirds and marine plastic pollution. Copyright © 2013 Elsevier Ltd. All rights reserved.

Incidence of vertebral hemangioma on spinal magnetic resonance imaging in Northern Iran.

PubMed

Barzin, M; Maleki, I

2009-03-15

The incidence of vertebral hemangiomas as the most common benign spinal neoplasms has been differently reported from 10 to 27% based on autopsy series, plain X-rays and MRI reviews. In this study, we reviewed consecutive 782 standard spinal MRI with axial and sagital T1 weighted and T2 weighted images looking for hemangiomas. In this study, the incidence of hemangioma was 26.9%, more common in females (30%) than males (23%), in older age group and in lumbar spine. Most hemangiomas (65%) were less than 10 mm in diameter. Multiple hemangiomas were seen in 33% of cases. The results of this study are similar to another Mediterranean study reported based on MRI findings, but differ from other reports using X-ray or autopsy as diagnostic tool, suggesting the influence of either the race or the sensitivity of the diagnostic tool on the incidence of vertebral hemangioma.

Comparison of Predicted and Measured Soil Retention Curve in Lombardy Region Northern of Italy

NASA Astrophysics Data System (ADS)

Wassar, Fatma; Rienzner, Michele; Chiaradia, Enrico Antonio; Gandolfi, Claudio

2013-04-01

Water retention characteristics are crucial input parameters in any modeling study on water flow and solute transport. These properties are difficult to measure and therefore the use of both direct and indirect methods is required in order to adequately describe them with sufficient accuracy. Several field methods, laboratory methods and theoretical models for such determinations exist, each having their own limitations and advantages (Stephens, 1994). Therefore, extensive comparisons between estimated, field and laboratory results to determine it still requires their validity for a range of different soils and specific cases. This study attempts to make a contribution specifically in this connection. The soil water retention characteristics were determined in two representative sites (PMI-1 and PMI-5) located in Landriano field, in Lombardy region, northern Italy. In the laboratory, values of both volumetric water content (θ) and soil water matric potential (h) are measured in the same sample using the tensiometric box and pressure plate apparatus. Field determination of soil water retention involved measurements of soil water content with SENTEK probes, and matric potential with tensiometers. The retention curve characteristics were also determined using some of the most commonly cited and some recently developed PTFs that use soil properties such as particle-size distribution (sand, silt, and clay content), organic matter or organic Carbon content, and dry bulk density. Field methods are considered to be more representative than laboratory and estimation methods for determining water retention characteristics (Marion et al., 1996). Therefore, field retention curves were compared against retention curves obtained from laboratory measurements and PTFs estimations. The performances of laboratory and PTFs in predicting field measured data were evaluated using root mean square error (RMSE) and bias. The comparison showed that laboratory measurements were the most

Incidence of acute-onset atrial fibrillation correlates with air temperature. Results of a nine-year survey.

PubMed

Comelli, Ivan; Ferro, Jayme; Lippi, Giuseppe; Comelli, Denis; Sartori, Elisabetta; Cervellin, Gianfranco

2014-09-01

Some diseases, such as renal colic, stroke, and myocardial infarction, correlate with seasonality and microclimatic variations. Although evidence is limited and controversial, a correlation between acute-onset atrial fibrillation (AAF) and seasonality has been previously reported. In order to elucidate the possible correlations between weather and incidence of AAF in a country with a temperate climate, the influence of day-by-day climate changes was analyzed based on the number of visits for AAF (defined as onset of symptoms within 48h) in a large urban Emergency Department (ED) of northern Italy. All the episodes of AAF were retrieved from the hospital's electronic database during a period of 3287days (January 2002 to December 2010). Only the cases whose onset occurred within 48h from the ED visit were selected. The total number of ED visits was 725,812 throughout the observational period. Among these, 3633 AAF cases were observed, 52% of which were males. A slight but significant negative linear correlation was found between the number of AAFs and the daily temperature (R=-0.60; p=0.001). No correlation was found between the number of AAFs and the daily humidity (R=-0.07; p=0.2). Copyright © 2014 Ministry of Health, Saudi Arabia. Published by Elsevier Ltd. All rights reserved.

Time-lapse electrical resistivity imaging of the thermally affected zone of a Borehole Thermal Energy Storage system near Torino (Northern Italy)

NASA Astrophysics Data System (ADS)

Giordano, N.; Arato, A.; Comina, C.; Mandrone, G.

2017-05-01

A Borehole Thermal Energy Storage living lab was built up nearby Torino (Northern Italy). This living lab aims at testing the ability of the alluvial deposits of the north-western Po Plain to store the thermal energy collected by solar thermal panels and the efficiency of energy storage systems in this climatic context. Different monitoring approaches have been tested and analyzed since the start of the thermal injection in April 2014. Underground temperature monitoring is constantly undertaken by means of several temperature sensors located along the borehole heat exchangers and within the hydraulic circuit. Nevertheless, this can provide only pointwise information about underground temperature distribution. For this reason, a geophysical approach is proposed in order to image the thermally affected zone (TAZ) caused by the heat injection: surface electrical resistivity measurements were carried out with this purpose. In the present paper, results of time-lapse acquisitions during a heating day are reported with the aim of imaging the thermal plume evolution within the subsoil. Resistivity data, calibrated on local temperature measurements, have shown their potentiality in imaging the heated plume of the system and depicting its evolution throughout the day. Different types of data processing were adopted in order to face issues mainly related to a highly urbanized environment. The use of apparent resistivity proved to be in valid agreement with the results of different inversion approaches. The inversion processes did not significantly improve the qualitative and quantitative TAZ imaging in comparison to the pseudo-sections. This suggested the usefulness of apparent resistivity data alone for a rough monitoring of TAZ in this kind of applications.

Late thrusting extensional collapse at the mountain front of the northern Apennines (Italy)

NASA Astrophysics Data System (ADS)

Tavani, Stefano; Storti, Fabrizio; Bausã, Jordi; MuñOz, Josep A.

2012-08-01

Thrust-related anticlines exposed at the mountain front of the Cenozoic Appenninic thrust-and-fold belt share the presence of hinterlandward dipping extensional fault zones running parallel to the hosting anticlines. These fault zones downthrow the crests and the backlimbs with displacements lower than, but comparable to, the uplift of the hosting anticline. Contrasting information feeds a debate about the relative timing between thrust-related folding and beginning of extensional faulting, since several extensional episodes, spanning from early Jurassic to Quaternary, are documented in the central and northern Apennines. Mesostructural data were collected in the frontal anticline of the Sibillini thrust sheet, the mountain front in the Umbria-Marche sector of the northern Apennines, with the aim of fully constraining the stress history recorded in the deformed multilayer. Compressional structures developed during thrust propagation and fold growth, mostly locating in the fold limbs. Extensional elements striking about perpendicular to the shortening direction developed during two distinct episodes: before fold growth, when the area deformed by outer-arc extension in the peripheral bulge, and during a late to post thrusting stage. Most of the the extensional deformation occurred during the second stage, when the syn-thrusting erosional exhumation of the structures caused the development of pervasive longitudinal extensional fracturing in the crestal sector of the growing anticline, which anticipated the subsequent widespread Quaternary extensional tectonics.

Dermatophytosis in northern Africa.

PubMed

Nweze, E I; Eke, I

2016-03-01

Infections caused by dermatophytes are a global problem and a major public health burden in the world today. In Africa, especially in the northern geographical zone, dermatophytic infections are being reported at an alarming rate. This is mostly because of some local but unique cultural practices, socioeconomic and environmental conditions, lack of reliable diagnostic personnel and facilities and ineffective treatment. Interestingly, the pathogen spectrum and the clinical manifestation are most times different from what is seen in other continents. Several epidemiological studies have been performed on the incidence and aetiology of dermatophytoses in northern Africa. However, there is currently no review article with up-to-date information on the relevant findings reported so far in this region. This information is necessary for clinicians who treat dermatophytic infections all over the world since agents of dermatophytes are no longer restricted because of the rapid mobility of humans from one part of the world to another. Moreover, the epidemiology of dermatophytoses is known to change over time, thus requiring the update of information from time to time. A review of relevant studies published on dermatophytoses in northern Africa is presented. This covers all of old Sudan, Algeria, Egypt, Libya, Tunisia and Morocco. © 2015 Blackwell Verlag GmbH.

Global Incidence of Preterm Birth.

PubMed

Tielsch, James M

2015-01-01

Estimating the incidence of preterm birth depends on accurate assessment of gestational age and pregnancy outcomes. In many countries, such data are not routinely collected, making global estimates difficult. A recent systematic approach to this problem has estimated a worldwide incidence of 11.1 per 100 live births in 2010. Significant variation in rates by country and region of the world was noted, but this variation is smaller than observed for a number of other important reproductive outcomes. Rates range from approximately 5% in some northern European countries to over 15% in some countries in sub-Saharan Africa and Asia. Time trends suggest that preterm birth incidence is increasing, but much of this change may reflect changes in medically induced early delivery practices as improvements in survival of preterm infants has improved. Whether there have been major changes in spontaneous preterm birth is unknown. New approaches to classifying etiologic heterogeneity have been proposed and offer the promise of developing specific interventions to address the range of underlying causes of this important health problem. © 2015 Nestec Ltd., Vevey/S. Karger AG, Basel.

Venice, Italy

NASA Technical Reports Server (NTRS)

2002-01-01

Four hundred bridges cross the labyrinth of canals that form the 120 islands of Venice, situated in a saltwater lagoon between the mouths of the Po and Piave rivers in northeast Italy. All traffic in the city moves by boat. Venice is connected to the mainland, 4 kilometers (2.5 miles) away, by ferries as well as a causeway for road and rail traffic. The Grand Canal winds through the city for about 3 kilometers (about 2 miles), dividing it into two nearly equal sections. According to tradition, Venice was founded in 452, when the inhabitants of Aquileia, Padua, and several other northern Italian cities took refuge on the islands of the lagoon from the Teutonic tribes invading Italy at that time.

This image was acquired on December 9, 2001 by the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) on NASA's Terra satellite. With its 14 spectral bands from the visible to the thermal infrared wavelength region, and its high spatial resolution of 15 to 90 meters (about 50 to 300 feet), ASTER will image Earth for the next 6 years to map and monitor the changing surface of our planet.

ASTER is one of five Earth-observing instruments launched December 18, 1999, on NASA's Terra satellite. The instrument was built by Japan's Ministry of Economy, Trade and Industry. A joint U.S./Japan science team is responsible for validation and calibration of the instrument and the data products.

The broad spectral coverage and high spectral resolution of ASTER will provide scientists in numerous disciplines with critical information for surface mapping, and monitoring dynamic conditions and temporal change. Example applications are: monitoring glacial advances and retreats; monitoring potentially active volcanoes; identifying crop stress; determining cloud morphology and physical properties; wetlands evaluation; thermal pollution monitoring; coral reef degradation; surface temperature mapping of soils and geology; and measuring surface heat balance.

Dr. Anne

Long-period amplification in deep alluvial basins and consequences for site-specific probabilistic seismic-hazard: the case of Castelleone in the Po Plain (Northern Italy)

NASA Astrophysics Data System (ADS)

Barani, S.; Mascandola, C.; Massa, M.; Spallarossa, D.

2017-12-01

The recent Emilia seismic sequence (Northern Italy) occurred at the end of the first half of 2012 with main shock of Mw6.1 highlighted the importance of studying site effects in the Po Plain, the larger and deeper sedimentary basin in Italy. As has long been known, long-period amplification related to deep sedimentary basins can significantly affect the characteristics of the ground-motion induced by strong earthquakes. It follows that the effects of deep sedimentary deposits on ground shaking require special attention during the definition of the design seismic action. The work presented here analyzes the impact of deep-soil discontinuities on ground-motion amplification, with particular focus on long-period probabilistic seismic-hazard assessment. The study focuses on the site of Castelleone, where a seismic station of the Italian National Seismic Network has been recording since 2009. Our study includes both experimental and numerical site response analyses. Specifically, extensive active and passive geophysical measurements were carried out in order to define a detailed shear-wave velocity (VS) model to be used in the numerical analyses. These latter are needed to assess the site-specific ground-motion hazard. Besides classical seismic refraction profiles and multichannel analysis of surface waves, we analyzed ambient vibration measurements in both single and array configurations. The VS profile was determined via joint inversion of the experimental phase-velocity dispersion curve with the ellipticity curve derived from horizontal-to-vertical spectral ratios. The profile shows two main discontinuities at depths of around 160 and 1350 m, respectively. The probabilistic site-specific hazard was assessed in terms of both spectral acceleration and displacement. A partially non-ergodic approach was adopted. We have found that the spectral acceleration hazard is barely sensitive to long-period (up to 10 s) amplification related to the deeper discontinuity whereas the

Incidence of malaria and risk factors in Italian travelers to malaria endemic countries.

PubMed

Romi, Roberto; Boccolini, Daniela; D'Amato, Stefania; Cenci, Corrado; Peragallo, Mario; D'Ancona, Fortunato; Pompa, Maria Grazia; Majori, Giancarlo

2010-05-01

Imported malaria has been an increasing problem in Italy in the last three decades of the 1900s, representing the main risk for travelers visiting tropical and sub-tropical countries where malaria is endemic. Even though the total number of imported cases has been declining since 2000, malaria still represents the most frequent notifiable imported disease in Italy. The present study analyzes all the malaria cases reported in Italy in 2000-2006 in order to assess the trend of incidence over the time and reviewing the risk factors for travelers visiting malaria endemic countries. All 2000-2006 case report forms were analyzed. The incidence of malaria in Italian travelers was calculated by continent and by countries most visited, using data provided by the Ministry of Transportation. Out of the 5219 malaria cases reported and confirmed in the study period five were autochthonous and 5214 imported, 1518 of which occurred in Italian citizen and 3696 in foreigners. Between 2000 and 2006 imported malaria cases fell from 977 to 630 respectively, with a total reduction of about 36%. Most of the cases were contracted in Africa (93%) and Plasmodium falciparum was the etiological agent in 83% of the cases, with an annual average fatality rate of about 0.5%. The average of the crude incidence rate (CIR) among Italians was calculated by continent for both global cases (gCIR) and for P. falciparum cases (pfCIR) resulting of 1.2/1000 and 0.9 for Africa, 0.08/1000 and 0.02 for Asia, 0.03/1000 and 0.003 for Central and South America, respectively. The gCIR by continent slightly but decreased constantly over the study period. The different factors which may influence the risk of contracting malaria for travelers visiting endemic countries and the strategy to reduce completely the number of fatal cases were considered and discussed. Copyright 2010 Elsevier Ltd. All rights reserved.

The 2012 Emilia earthquake in northern Italy: coseismic geological effects within a compressive tectonic framework

NASA Astrophysics Data System (ADS)

Montone, P.; Alessio, G.; Alfonsi, L.; Brunori, C.; Burrato, P.; Casula, G.; Cinti, F. R.; Civico, R.; Colini, L.; Cucci, L.; De Martini, P. M.; Falcucci, E.; Galadini, F.; Gaudiosi, G.; Gori, S.; Mariucci, M.; Moro, M.; Nappi, R.; Nardi, A.; Nave, R.; Pantosti, D.; Patera, A.; Pesci, A.; Pignone, M.; Pinzi, S.; Pucci, S.; Vannoli, P.; Venuti, A.; Villani, F.

2012-12-01

On May 20 2012 a Ml 5.9 seismic event hit the Emilia Po Plain area (northern Italy) triggering an intense earthquake activity along a broad area of the Plain. Nine days later, on May 29 a Ml 5.8 event occurred roughly 10 km to the SW of the first main shock; these events caused 26 victims and several injured and damages. The aftershock area extended for more than 50 km, in WNW-ESE direction, including five major aftershocks with 5.1≤Ml≤5.3 and more than two thousands of minor events. In general, the seismic sequence was confined in the upper 10 km of depth (ISIDe, http://iside.rm.ingv.it/). The focal mechanisms calculated for the main events and also for several M>4.5 aftershocks are almost all consistent with a compression (P-axes) N-S oriented due to thrust fault mechanisms. The two nodal planes, both E-W oriented, show a 40° southward and 60-70° northward dipping plane (QRCMT, Quick Regional Moment Tensors, http://autorcmt.bo.ingv.it/quicks.html), connected with the compressional regime of the area. From a tectonic point of view, the active Apennine thrust fronts, buried under the Po Plain Plio-Quaternary sediments, locally consist of three N-verging arcs. The most external structures, the active Ferrara and Mirandola thrusts and folds are responsible for the Emilia Romagna 2012 earthquake sequence. Just after the 20th May seismic event, the EMERGEO Working Group was active in surveying the epicentral area searching for coseismic geological effects. The survey lasted one month, involving about thirty researchers and technicians of the INGV in field and aerial investigations. Simultaneously, a laboratory-working group gathered, organized and interpreted the observations, processing them in the EMERGEO Information System (siE), on a GIS environment. The most common coseismic effects are: 1) liquefactions related to overpressure of aquifers hosted in buried and confined sand layers, occurring both as single cones or through several aligned vents forming

Active deformation and seismicity in the Southern Alps (Italy): The Montello hill as a case study

NASA Astrophysics Data System (ADS)

Danesi, Stefania; Pondrelli, Silvia; Salimbeni, Simone; Cavaliere, Adriano; Serpelloni, Enrico; Danecek, Peter; Lovati, Sara; Massa, Marco

2015-06-01

The Montello anticline is a morphotectonic feature of the east pede-mountain of the South Alpine Chain in northern Italy, which lies ca. 40 km northwest of Venice, Italy. The purpose of this study is to characterize the present-day crustal deformation and seismotectonics of the Montello area through multi-parametric geophysical observations. We used new data obtained from the installation of a temporary network of 12 seismic stations and 6 GPS sites. The GPS observations indicate that there is ~ 1 mm/yr shortening across the Montello thrust. Sites located north of the Montello thrust front deviate from the ~ NNW-ward Adria-Eurasia convergence direction, as they are constrained by a relative rotation pole in northwestern Italy that has a NNE-ward motion trend. Over 18 months, seismographic recordings allowed us to locate 142 local seismic events with Ml 0.5-3.5 with good reliability (rms < 0.5). After cross-correlation analysis, we classified 42 of these events into six clusters, with cross-correlation thresholds > 0.80. The source focal solutions indicate that: (i) there is thrusting seismic activity on the basal, sub-horizontal, portion of the Montello structure; and (ii) strike-slip source kinematics prevail on the western edge of the Montello hill. Our observations on the source mechanisms and the measured crustal deformation confirm that the Montello thrust is tectonically active.

Fires in Australia's Northern Territory and Bathurst Island

NASA Image and Video Library

2017-12-08

The Aqua satellite collected this natural-color image of fires in Australia with the Moderate Resolution Imaging Spectroradiometer (MODIS) instrument on June 30, 2017. The image looks at multiple fires and smoke from those fires burning in northern Australia and the island of Bathurst on June 30, 2017. The Northern Territory fire incident map does show some incidents of grass and shrub fires, in the past 24 hours, but it also shows areas of what are called "strategic fires" which are those set by fire experts to rid an area of overgrowth, brush, dead grass and shrubs to prevent fires from spreading in the event of a lightning strike. NASA image courtesy Jeff Schmaltz, MODIS Rapid Response Team NASA image use policy. NASA Goddard Space Flight Center enables NASA’s mission through four scientific endeavors: Earth Science, Heliophysics, Solar System Exploration, and Astrophysics. Goddard plays a leading role in NASA’s accomplishments by contributing compelling scientific knowledge to advance the Agency’s mission. Follow us on Twitter Like us on Facebook Find us on Instagram

Sunshine duration and global radiation trends in Italy (1959-2013): To what extent do they agree?

NASA Astrophysics Data System (ADS)

Manara, V.; Brunetti, M.; Maugeri, M.; Sanchez-Lorenzo, A.; Wild, M.

2017-04-01

Two Italian homogenized data sets of sunshine duration (SD) and global radiation (Eg↓) relative anomalies are used to investigate to what extent these two variables agree with respect to their temporal evolution. They are compared for northern and southern Italy over the period 1959-2013. Both under all-sky and clear-sky conditions, the SD records tend to show a shorter and less intense decrease until the 1980s ("global dimming") with respect to the Eg↓ ones, while there is a better agreement in the subsequent period when both variables increase ("brightening period"). To investigate whether such behavior can be explained by a different sensitivity of SD and Eg↓ to atmospheric turbidity variations, the observed clear-sky trends are compared to those estimated by a model based both on Lambert-Beer's law and on a simple estimation of diffuse radiation. Results show that most of the differences observed in the trends of the clear-sky SD and Eg↓ records can be explained considering a realistic pattern of atmospheric turbidity in the 1959-2013 period. The only exception concerns winter and autumn in northern Italy where clear-sky SD does not decrease in the dimming period as much as it would be expected on the basis of the corresponding increase in atmospheric turbidity. One reason for this discrepancy could be the influence of other variables like relative humidity. This case study highlights that changes in atmospheric turbidity have to be kept in mind when SD is used to investigate the multidecadal evolution of Eg↓.

Insights on the opening of the Galerian mammal migration pathway from magnetostratigraphy of the Pleistocene marine-continental transition in the Arda River section (northern Italy)

NASA Astrophysics Data System (ADS)

Monesi, Edoardo; Muttoni, Giovanni; Scardia, Giancarlo; Felletti, Fabrizio; Bona, Fabio; Sala, Benedetto; Tremolada, Fabrizio; Francou, Carlo; Raineri, Gianluca

2016-09-01

We investigated the magnetostratigraphy of the Arda River section (northern Italy) where the transition from marine to continental sedimentation occurring in the Po River basin during the Pleistocene is registered. Four magnetic polarity reversals were used to construct an age model of sedimentation aided by marine biostratigraphy and tied to a standard δ18O curve from the literature. The section spans from the Olduvai subchron (1.94-1.78 Ma) across the Jaramillo subchron (1.07-0.99 Ma) up to the Brunhes-Matuyama boundary (0.78 Ma). The onset of continental deposition occurred during marine isotope stage (MIS) 30 at ˜1.04 Ma. An association of Villafranchian and Early Galerian mammals, including Sus strozzii and Ursus dolinensis, has been found in the continental sediments dated to MIS 29-27 (˜0.99 Ma). Above follows a prominent fluvial conglomerate attributed to the first major lowstand of the Pleistocene culminating with MIS 22 at ˜0.9 Ma during the late Early Pleistocene climate turnover (EPT). These and other data from the literature are used to reconstruct the onset of continental deposition in the greater Po basin and shed light on the opening of the migration pathway that brought far-traveled Galerian mammal immigrants to enter Europe for the first time during the EPT.

A cross-sectional study of PRNP gene in two native Sicilian goat populations in Italy: a relation between prion gene polymorphisms and scrapie incidence.

PubMed

Migliore, Sergio; Agnello, Stefano; D'Avola, Salvatore; Goldmann, Wilfred; Di Marco Lo Presti, Vincenzo; Vitale, Maria

2017-06-01

Transmissible spongiform encephalopathies (TSEs) are a group of neurodegenerative diseases affecting humans and animals, and scrapie in small ruminants is considered the archetype of TSEs. Derivata di Siria is a native dairy goat of Sicily (south Italy), which is related to Syrian goat breeds. Scrapie disease is considered endemic in Sicily since 1997, following the administration of an infected vaccine.Derivata di Siria goatswere involved in six of 66 scrapie-infected flocks in Sicily. Prion protein gene (PRNP) analysis revealed that none of the scrapie cases carried the p.Gln222Lys variant. Sequencing of PRNP in this goat population showed a high frequency (15%) of p.Gln222Lys variant confirming its association with scrapie resistance. PRNP polymorphisms were also analysed in the population of Pantelleria, a small Sicilian Island, where scrapie has never been reported. The native goat breed 'Pantesca' was maintained up to almost 80 years and the size of the sheep population on this island has historically been very low. Currently, a crossbreed goat population of 253 heads is present on the island. PRNP genotyping of Pantelleria goats showed genetic variation, with low presence of wild-type goats and the lack of protective alleles. These data reinforce the association between PRNP polymorphisms in small ruminants and scrapie incidence.

The persistent challenge of rheumatic fever in the Northern Mariana Islands.

PubMed

Seckeler, Michael D; Barton, Leslie L; Brownstein, Rachel

2010-03-01

Acute rheumatic fever (ARF) is a major cause of morbidity and mortality in developing nations. The objective of this study was to determine the disease burden of ARF among the indigenous and non-indigenous populations of the Northern Mariana Islands. This was a chart review of all pediatric outpatients seen from 1984 to 2006 with ICD-9 codes corresponding to rheumatic fever or any rheumatic cardiac sequelae. The study was set in the only comprehensive inpatient facility and only public pediatric clinic in the Northern Mariana Islands. One hundred fifty-eight cases of ARF were identified. Age at diagnosis ranged from 2.9 to 17.1 years (median 10.6 years). Fever and carditis were the most common presenting findings. The average annualized incidence of ARF was 85.8 per 100,000 person-years for those aged 5-14 years. Sixty-six percent of patients with ARF were of Chamorro or Carolinian ancestry, despite comprising only 39% of the total population, with a combined average annualized incidence of ARF of 167 per 100,000 person-years. This is the first documentation of the incidence of pediatric ARF in the Northern Mariana Islands, delineating the large disease burden in the indigenous and other Pacific Island ethnic groups. Impediments to diagnosis and primary and secondary prevention were identified. The data provide strong support for the need for primary and secondary prevention of ARF. Copyright 2009 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.

Low frequency amplification in deep alluvial basins: an example in the Po Plain (Northern Italy) and consequences for site specific SHA

NASA Astrophysics Data System (ADS)

Mascandola, Claudia; Massa, Marco; Barani, Simone; Lovati, Sara; Santulin, Marco

2016-04-01

This work deals with the problem of long period seismic site amplification that potentially might involve large and deep alluvial basins in case of strong earthquakes. In particular, it is here presented a case study in the Po Plain (Northern Italy), one of the most extended and deep sedimentary basin worldwide. Even if the studied area shows a low annul seismicity rate with rare strong events (Mw>6.0) and it is characterized by low to medium seismic hazard conditions, the seismic risk is significant for the high density of civil and strategic infrastructures (i.e. high degree of exposition) and the unfavourable geological conditions. The aim of this work is to provide general considerations about the seismic site response of the Po Plain, with particular attention on deep discontinuities (i.e. geological bedrock), in terms of potential low frequency amplification and their incidence on the PSHA. The current results were obtained through active and passive geophysical investigations performed near Castelleone, a site where a seismic station, which is part of the INGV (National Institute for Geophysics and Volcanology) Seismic National Network, is installed from 2009. In particular, the active analyses consisted in a MASW and a refraction survey, whereas the passive ones consisted in seismic ambient noise acquisitions with single stations and arrays of increasing aperture. The results in terms of noise HVSR indicate two main peaks, the first around 0.17 Hz and the second, as already stated in the recent literature, around 0.7 Hz. In order to correlate the amplified frequencies with the geological discontinuities, the array acquisitions were processed to obtain a shear waves velocity profile, computed with a joint inversion, considering the experimental dispersion curves and the HVSR results. The obtained velocity profile shows two main discontinuities: the shallower at ~165 m of depth, which can be correlated to the seismic bedrock (i.e. Vs > 800 m/) and the deeper

Epidemiology and economic burden of herpes zoster and post-herpetic neuralgia in Italy: A retrospective, population-based study

PubMed Central

2010-01-01

Background Data on the epidemiology and cost of herpes zoster (HZ) and post-herpetic neuralgia (PHN) in Italy are limited. This retrospective, population-based study was designed to determine the incidence of HZ and the proportion developing PHN in Italy and the associated medical resource utilisation and costs. It focused primarily on immunocompetent patients aged ≥50 years who would be eligible for preventive vaccination. Method Data were extracted from a primary-care database and national hospital-discharge records covering four major regions in Italy for 2003-2005. Cases of HZ and PHN (1 and 3 months' duration; PHN1 and PHN3) were identified by ICD9-CM codes and, additionally for PHN, prescription of neuropathic pain medication. Results Over 3 years, 5675 incident cases of HZ were documented in adults, of which 3620 occurred in immunocompetent patients aged ≥50 years (incidence of 6.31 per 1000 person-years [95% CI: 6.01-6.62]). Of the immunocompetent patients aged ≥50 years with HZ, 9.4% (95% CI: 8.2-10.7) and 7.2% (95% CI: 6.2-8.2) developed PHN1 and PHN3, respectively. Increasing age, female sex, and being immunologically compromised conferred increased risk for both HZ and PHN. Overall, about 1.3% of HZ and almost 2% of PHN cases required inpatient care, with 16.9% of all HZ-related hospitalisations due specifically to PHN. In patients aged ≥50 years, mean stay was 7.8 ± 5.4 days for HZ and 10.2 ± 8.6 days for PHN, and direct costs associated with inpatient care were more than 20 times outpatient costs per HZ case (mean ± SD: €2592 ± €1313 vs. €122.68 ± €97.51) and over 5 times more per episode of PHN (mean ± SD: €2806 ± €2641 vs. €446.10 ± €442.97). Total annual costs were €41.2 million, of which €28.2 million were direct costs and €13.0 million indirect costs. Conclusions This study, the largest to date on the epidemiology and economic impact of HZ and PHN in Italy, confirms the considerable disease and economic

A one-year prospective study of refractory status epilepticus in Modena, Italy.

PubMed

Giovannini, Giada; Monti, Giulia; Polisi, Michela M; Mirandola, Laura; Marudi, Andrea; Pinelli, Giovanni; Valzania, Franco; Girardis, Massimo; Nichelli, Paolo F; Meletti, Stefano

2015-08-01

Refractory status epilepticus (RSE) is a particular critical condition characterized by seizures that continue despite the use of first- and second-line therapies and by high mortality. To date, only one prospective study investigated clinical features and prognostic factors in RSE. In this study, we performed a one-year prospective survey to identify clinical features, outcomes, and variables associated with the development of RSE in the adolescent and adult population of Modena, northern Italy. We observed 83 episodes of SE in 83 patients. In 31% of the cases, third-line therapy (anesthetic drug) was needed. Among this group, 14% resolved and were classified as RSE, while, in 17%, seizures recurred at withdrawal of anesthetics and were classified as super-RSE. The development of RSE/super-RSE was associated with a stuporous/comatose state at presentation and with the absence of a previous history of epilepsy. Refractory status epilepticus/super-refractory status epilepticus showed a worse outcome compared with responsive SE: 54% versus 21% for 30-day mortality; 19% versus 56% for a return to baseline condition. This prospective study confirms stupor/coma at onset as a relevant clinical factor associated with SE refractoriness. We observed a rate of RSE comparable with previous reports, with high mortality and morbidity. Mortality in the observed RSE was higher than in previous studies; this result is probably related to the low rate of a previous epilepsy history in our population that reflects a high incidence of acute symptomatic etiologies, especially the inclusion of patients with postanoxic SE who have a bad prognosis per se. This article is part of a Special Issue entitled "Status Epilepticus". Copyright © 2015 Elsevier Inc. All rights reserved.

Epidemiology of tetanus in the Marches Region of Italy, 1992-95.

PubMed Central

Prospero, E.; Appignanesi, R.; D'Errico, M. M.; Carle, F.

1998-01-01

Reported is the incidence of tetanus in the Marches Region of Italy for the period 1992-95. Data were obtained from both the regional public health committee's notification forms for infectious diseases and from hospital clinical records. A total of 36 cases were examined, comprising 7 males (19.4%) and 29 females. The raw annual incidence was 6.3 per million population; the standardized incidence for females was four times greater than that for males (9.2 and 2.4 per million population annually, respectively). The patients' ages varied from 31 years to 88 years (median, 73.5 years). The incidence among subjects older than 65 years was approximately ten times greater than that among younger individuals. Chronic wounds, such as trophic lesions, represented the site of tetanus infection in 14.3% of cases whose infection entry point was identified. Treatment of the 36 cases required a total of 1239 hospital days, of which 58.7% were in intensive care and 29.6% were in infectious diseases departments. The raw annual mortality rate for the period considered was 0.7 per million population; the case-fatality ratio was 11%. The results of our study confirm the limits of the current Italian immunization programmes, which exclude a large portion of the population from antitetanus protection. PMID:9615496

Arthropod-borne diseases in Italy: from a neglected matter to an emerging health problem.

PubMed

Romi, Roberto

2010-01-01

In medical entomology, "Arthropod Borne Diseases", or "Vector Borne Diseases" (VBD) are intended as a group of human and animal infections caused by different pathogen organisms (protozoa, helminths, bacteria and viruses) transmitted by the bite of a bloodsucking insect or arachnid. It is commonly known that the infectious diseases transmitted by Arthropods are mainly affecting tropical and subtropical countries, nevertheless some of them were or are still common also in the northern hemisphere, where they are usually maintained under control. VBD still represent some of the most important public health problems in the endemic areas but are becoming source of concern for developed countries too. Since the last decades of the past century, a number of VBD has been spreading geographically, being recorded for the first time in areas outside their original range. This phenomenon is strictly related to the peculiar epidemiological characteristics of these diseases, that are considered the most susceptible to climatic, environmental and socioeconomic changes. This article is a short overview of the VBD endemic and emerging in Italy. The possibility that some exotic vectors and/or pathogens could be introduced and become established in Italy is also discussed.

Epidemiology and costs of cervical cancer screening and cervical dysplasia in Italy

PubMed Central

Rossi, Paolo Giorgi; Ricciardi, Alessandro; Cohet, Catherine; Palazzo, Fabio; Furnari, Giacomo; Valle, Sabrina; Largeron, Nathalie; Federici, Antonio

2009-01-01

Background We estimated the number of women undergoing cervical cancer screening annually in Italy, the rates of cervical abnormalities detected, and the costs of screening and management of abnormalities. Methods The annual number of screened women was estimated from National Health Interview data. Data from the Italian Group for Cervical Cancer Screening were used to estimate the number of positive, negative and unsatisfactory Pap smears. The incidence of CIN (cervical intra-epithelial neoplasia) was estimated from the Emilia Romagna Cancer Registry. Patterns of follow-up and treatment costs were estimated using a typical disease management approach based on national guidelines and data from the Italian Group for Cervical Cancer Screening. Treatment unit costs were obtained from Italian National Health Service and Hospital Information System of the Lazio Region. Results An estimated 6.4 million women aged 25–69 years undergo screening annually in Italy (1.2 million and 5.2 million through organized and opportunistic screening programs, respectively). Approximately 2.4% of tests have positive findings. There are approximately 21,000 cases of CIN1 and 7,000–17,000 cases of CIN2/3. Estimated costs to the healthcare service amount to €158.5 million for screening and €22.9 million for the management of cervical abnormalities. Conclusion Although some cervical abnormalities might have been underestimated, the total annual cost of cervical cancer prevention in Italy is approximately €181.5 million, of which 87% is attributable to screening. PMID:19243586

The "Mud-volcanoes route" (Emilia Apennines, northern Italy)

NASA Astrophysics Data System (ADS)

Coratza, Paola; Castaldini, Doriano

2016-04-01

In the present paper the "Mud-volcanoes route" (MVR), an itinerary unfolds across the districts of Viano, Sassuolo, Fiorano Modenese and Maranello, in which part of the Emilia mud volcanoes fields are located, is presented. The Mud-volanoes route represents an emotional journey that connects places and excellences through the geological phenomenon of mud volcanoes, known with the local name "Salse". The Mud Volcanoes are created by the surfacing of salt water and mud mixed with gaseous and liquid hydrocarbons along faults and fractures of the ground. The name "Salsa"- from Latin salsus - results from the"salt" content of these muddy waters, ancient heritage of the sea that about a million years ago was occupying the current Po Plain. The "Salse" may take the shape of a cone or a level-pool according to the density of the mud. The Salse of Nirano, in the district of Fiorano Modenese, is one of the most important in Italy and among the most complex in Europe. Less extensive but equally charming and spectacular, are the "Salse" located in the districts of Maranello (locality Puianello), Sassuolo (locality Montegibbio) and Viano (locality Casola Querciola and Regnano). These fascinating lunar landscapes have always attracted the interest of researchers and tourist.The presence on the MVR territory of ancient settlements, Roman furnaces and mansions, fortification systems and castles, besides historic and rural buildings, proves the lasting bond between this land and its men. In these places, where the culture of good food has become a resource, we can find wine cellars, dairy farms and Balsamic vinegar factories that enable us to appreciate unique worldwide products. This land gave also birth to some personalities who created unique worldwide famous values, such as the myth of the Ferrrari, the ceramic industry and the mechatronics. The MVR is represented in a leaflet containing, short explanation, photos and a map in which are located areas with mud volcanoes, castles

International variations and trends in renal cell carcinoma incidence and mortality.

PubMed

Znaor, Ariana; Lortet-Tieulent, Joannie; Laversanne, Mathieu; Jemal, Ahmedin; Bray, Freddie

2015-03-01

Renal cell carcinoma (RCC) incidence rates are higher in developed countries, where up to half of the cases are discovered incidentally. Declining mortality trends have been reported in highly developed countries since the 1990s. To compare and interpret geographic variations and trends in the incidence and mortality of RCC worldwide in the context of controlling the future disease burden. We used data from GLOBOCAN, the Cancer Incidence in Five Continents series, and the World Health Organisation mortality database to compare incidence and mortality rates in more than 40 countries worldwide. We analysed incidence and mortality trends in the last 10 yr using joinpoint analyses of the age-standardised rates (ASRs). RCC incidence in men varied in ASRs (World standard population) from approximately 1/100,000 in African countries to >15/100,000 in several Northern and Eastern European countries and among US blacks. Similar patterns were observed for women, although incidence rates were commonly half of those for men. Incidence rates are increasing in most countries, most prominently in Latin America. Although recent mortality trends are stable in many countries, significant declines were observed in Western and Northern Europe, the USA, and Australia. Southern European men appear to have the least favourable RCC mortality trends. Although RCC incidence is still increasing in most countries, stabilisation of mortality trends has been achieved in many highly developed countries. There are marked absolute differences and opposing RCC mortality trends in countries categorised as areas of higher versus lower human development, and these gaps appear to be widening. Renal cell cancer is becoming more commonly diagnosed worldwide in both men and women. Mortality is decreasing in the most developed settings, but not in low- and middle-income countries, where access to and the availability of optimal therapies are likely to be limited. Copyright © 2014 European Association of

Syenite and diorite: a unique stone heritage in north of Italy

NASA Astrophysics Data System (ADS)

Tori, Alice; Marini, Paula; Zichella, Lorena; Bellopede, Rossana

2015-04-01

The Syenite from the Cervo Torrent Valley near Biella in northern Italy has been widely used as a building material. During the XXth century it has been exported all over the World for covering and paving slabs and monumental work. It is an intrusive magmatic rock found in the Cervo Valley pluton, which is part of the Balma pluton. It formed about 30 million years ago as a result of the Alpine Orogeny and is known to be post-orogenic because of the absence of metamorphism. Hydrothermal mineralization associated with the pluton includes minerals of molybdenum, tungsten, copper, lead, silver and gold. Utilisation of the Syenite has been the only industrial activity in the high Cervo Valley sustaining the whole of valley life. During the second half of the XIXth century and during the first part of the XXth the competencies and the working skills of the Cervo Valley stonecutters was exported as far as Perù and China. It was e.g. used for the edification and refinement of the Oropa Sanctuary square in Piedmont, Italy. It has been recognized as an interesting building material because of the intrinsic characteristics such as its resistance to mechanical wear, durability of colour tone and intensity and resistance to water wear (e.g. in fountains) and maintains its mechanical integrity over time. Diorite is also a magmatic intrusive rock and, similar to the syenite, differs from granite due to the low concentration of quartz (<10%). It consists of plagioclase, pyroxene, amphibole and quartz. It is exploited at the Vico Canavese quarry, near Turin, Italy. It is easy to cut and to process with the suitable tools. It has a number of variants, each with specific characteristics and behavior. It is multipurpose material and consequently it can be used in different shape and application, such as slabs, covering, bed river, building block and tiles. Although mainly used in Italy, it has also been used world wide for many different constructional and aesthetic purposes. These

Flood damage in Italy: towards an assessment model of reconstruction costs

NASA Astrophysics Data System (ADS)

Sterlacchini, Simone; Zazzeri, Marco; Genovese, Elisabetta; Modica, Marco; Zoboli, Roberto

2016-04-01

Recent decades in Italy have seen a very rapid expansion of urbanisation in terms of physical assets, while demographics have remained stable. Both the characteristics of Italian soil and anthropic development, along with repeated global climatic stress, have made the country vulnerable to floods, the intensity of which is increasingly alarming. The combination of these trends will contribute to large financial losses due to property damage in the absence of specific mitigation strategies. The present study focuses on the province of Sondrio in Northern Italy (area of about 3,200 km²), which is home to more than 180,000 inhabitants and the population is growing slightly. It is clearly a hot spot for flood exposure, as it is primarily a mountainous area where floods and flash floods hit frequently. The model we use for assessing potential flood damage determines risk scenarios by overlaying flood hazard maps and economic asset data. In Italy, hazard maps are provided by Regional Authorities through the Hydrogeological System Management Plan (PAI) based on EU Flood Directive guidelines. The PAI in the study area includes both the large plain and the secondary river system and considers three hazard scenarios of Low, Medium and High Frequency associated with return periods of 20, 200 and 500 years and related water levels. By an overlay of PAI maps and residential areas, visualized on a GIS, we determine which existing built-up areas are at risk for flood according to each scenario. Then we investigate the value of physical assets potentially affected by floods in terms of market values, using the database of the Italian Property Market Observatory (OMI), and in terms of reconstruction costs, by considering synthetic cost indexes of predominant building types (from census information) and PAI water height. This study illustrates a methodology to assess flood damage in urban settlements and aims to determine general guidelines that can be extended throughout Italy

[Analysis on the epidemiological features of human brucellosis in northern and southern areas of China, 2015-2016].

PubMed

Shi, Y J; Lai, S J; Chen, Q L; Mu, D; Li, Y; Li, X X; Yin, W W; Yu, H J

2017-04-10

Objective: To analyze the epidemiological characteristics of human brucellosis in northern and southern areas of China, and to develop national strategies for brucellosis prevention and control. Methods: Individual data on human brucellosis was collected from the National Notifiable Infectious Disease Reporting Information System to describe the situation of brucellosis in China during 2015-2016. Epidemiological features of the disease in northern and southern areas of China were analyzed. Results: A total of 104 125 cases were reported in mainland China during 2015-2016, with an average incidence rate as 3.81/100 000. The overall incidence rate from the northern provinces was 7.77/100 000 in 2016, a 18.6 % decrease from 2015 (9.55/100 000), whereas the incidence rate in the southern provinces was 0.27/100 000 in 2016, with an increase of 28.6 % than 0.21/100 000 in 2015. 90.0 % of the newly infected counties mainly distributed in southern China. As for the locations of reporting cases, most of them were in the same counties in the northern areas (52.3 % ) while most cases in the southern areas (59.6 % ) were imported from other counties. The median age of the cases was 48 ( IQR: 38-58) years, with male-to-female ratios as 2.7∶1 in the north and 2.2∶1 in the south. Majority of the cases were occupation-related, from both the northern (86.8 % ) and southern (62.7 % ) areas. Human brucellosis occurred every month throughout the year but with an obvious seasonal increase between March and July. Conclusions: Different epidemiological features of human brucellosis appeared in both northern and southern areas of China. The disease was seen endemic in the northern and dispersal in the southern provinces. Appropriate strategies for brucellosis prevention and control should be developed, according to the different epidemiological characteristics in the northern or southern areas.

Measles in Italy: Co-circulation of B3 variants during 2014.

PubMed

Magurano, Fabio; Baggieri, Melissa; Bordi, Licia; Lalle, Eleonora; Chironna, Maria; Lazzarotto, Tiziana; Amendola, Antonella; Baldanti, Fausto; Ansaldi, Filippo; Filia, Antonietta; Declich, Silvia; Iannazzo, Stefania; Pompa, Maria Grazia; Bucci, Paola; Marchi, Antonella; Nicoletti, Loredana

2016-06-01

In 2013, the majority of the WHO/EUR countries reported an annual incidence of >1 case per one million population indicating that the elimination target is far from being met. Thus, there is the urgent need to uncover and analyze chains of measles virus (MV) transmission with the objective to identify vulnerable groups and avoid possible routes of introduction of MV variants in the European population. The analysis of molecular epidemiology of MV B3 strains identified in 2014 has shown that four different variants co-circulated in Italy, including the strain that caused a cruise-line ship outbreak at the beginning of the year. © 2015 Wiley Periodicals, Inc.

Nutritional status, dietary habits, nutritional knowledge and self-care assessment in a group of older adults attending community centres in Pavia, Northern Italy.

PubMed

Turconi, G; Rossi, M; Roggi, C; Maccarini, L

2013-02-01

The population of industrialised countries is ageing as a consequence of an increase in life expectancy. As a result of the increasing ageing process, the assessment of nutritional status and dietary habits, as well as the assessment of self-care, is needed to plan selected actions aimed at improving the quality of life in the third and fourth life spans. A cross-sectional study was carried out on a randomly selected sample of 200 healthy older adults (≥65 years old), attending community centres for older people in Pavia, Northern Italy. Ninety-two percent of the recruited subjects participated in the survey. Anthropometric measurements and the Mini Nutritional Assessment were performed. Dietary habits, nutritional knowledge and self-care were investigated using a questionnaire administered by two dietitians. The majority of subjects were low socio-economic status and overweight [mean (SD) body mass index = 28.4 (4.3) kg/m(2) ], 12% were malnourished according to their Mini Nutritional Assessment score and the majority of the arm muscle circumference measurements were below the 10th percentile, predicting accelerated loss of lean mass, even in the healthy independently living older adults. Only 30% of the sample had adequate dietary habits, whereas the ability to self-care was good for the whole sample. The unhealthy and unbalanced diet, frequently too rich in sugar and fats and low in protein intake, might explain being overweight and the loss of lean mass in the study subjects. © 2012 The Authors Journal of Human Nutrition and Dietetics © 2012 The British Dietetic Association Ltd.

Anatomy of biocalcarenitic units in the Plio-Pleistocene record of the Northern Apennines (Italy)

NASA Astrophysics Data System (ADS)

Cau, Simone; Roveri, Marco; Taviani, Marco

2017-04-01

The Castell'Arquato Basin (CAB) in the foothills of the thrust-belt Northern Apennines is a foreland basin infilled by Plio-Quaternary sediments and a reference area for Plio-Pleistocene biostratigraphy. The CAB exposes plurimetric biodetrital carbonate units at discrete temporal intervals. Such shell-rich units are at places lithified, turning into conspicuous biodetritral carbonate rocks (biocalcarenites) that display a cyclical stacking motif highlighted by the regular alternation with finer-grained marine deposits. The cyclical nature of thick biocalcarenites has been hypothesized to be orbitally-controlled by obliquity and/or precession cyclicity. Furthermore, biocalcarenite-mudstone couplets form distinct clusters governed by 100-400 ka eccentricity maxima starting from 3.1 Ma at the inception of the Northern Hemisphere glaciation. They correlate with sapropels cycles formed at times of maximum insolation (precession minima). The CAB calcarenites are poorly known with respect to their environmental genetic context what motivated a detailed paleoecological analysis to unravel at best their formative context. Five distinct biofacies arranged in stacking patterns are identified through two-way cluster analysis based on the macrofossil content. Our quantitative and qualitative results suggest that these polytaxic shell concentrations and their bracketing marine mudstones developed in middle shelf settings being sensitive to climatically-driven changes.

Tuberculosis in the immigrant population in Italy: state-of-the-art review.

PubMed

Scotto, Gaetano; Fazio, Vincenzina; Lo Muzio, Lorenzo

2017-09-01

Although the incidence of tuberculosis (TB) has been decreasing in the European Union/European Economic Area (EU/EEA) in recent decades, specific subgroups of the population, such as immigrants, remain at high risk of the disease. Immigration from areas of high incidence is thought to have fuelled the resurgence of TB in areas of low incidence. Indeed, while immigrants have a high risk of acquiring TB prior to migration, after migration they are exposed to additional risk factors for acquiring or reactivating TB infection, such as poverty, stressful living conditions, social inequalities, overcrowded housing, malnutrition, substance abuse and limited access to health care. In Italy as well, TB has increasingly become a disease for specific population subgroups such as immigrants and in urban settings often driven by reactivation of imported latent TB infection (LTBI). In this paper we present an analysis of the national scientific literature from recent years in order to estimate the burden of TB in foreign-born populations, to establish the burden of TB in migrants by gender, age group and country of origin as well as other relevant subgroups, and evaluate the clinical manifestations of latent or active tuberculosis and treatment response.

The "green stones" of Valtellina and Valchiavenna (central Alps, northern Italy)

NASA Astrophysics Data System (ADS)

Cavallo, Alessandro

2015-04-01

Valtellina and Val Chiavenna (Sondrio, Central Alps, northern Italy) are traditionally areas of production of building and ornamental stones (e.g. Serizzo Ghiandone, Serizzo Valmasino, San Fedelino Granite), and among these the "green stones" have a leading position. These stones had an extensive use in Lombardy, as well as abroad (e.g Switzerland). The "green stones" are related to the two mafic-ultramafic bodies of Valmalenco and Chiavenna, where the two largest quarrying districts of the Province of Sondrio are located. Until the early decades of the XX century, serpentinites (and other lithologies from Valtellina) were also extracted from the erratic boulders of Brianza (north of Milan), but at present time the law protects the few remaining boulders. The extracted and processed materials are various: serpentinites, ophicalcites, soapstones. Even the "Stone of Tresivio", used in the past in important monuments of Valtellina, could be classified among the "green stones" in a broad sense: it is a green chloritic schist with scarce and thin ferriferous calcitic veins, pertaining to the sedimentary "Servino" Formation. In recent times, the ancient quarries of this stone were rediscovered near the homonymous village, a few kilometers from Sondrio. There are also historic reports about other "green stones", used in ancient times, such as the "Stone of Grosio", a chloritic schist, and the "Bormio Prasinite". Currently the extraction and processing of "green stones" occurs mostly in Valmalenco, with 22 active serpentinite quarries and a gross volume of 70000 m3 extracted per year, with a yield of about 50%. The Malenco serpentinite (interpreted as sub-continental mantle rocks) forms a 1-2 km thick tabular body, outcropping over an area of about 170 km2, almost entirely confined within the boundaries of the valley. The antigoritic serpentinites (with variable amounts of olivine, clinopyroxene, chlorite and magnetite) are moderately up to strongly foliated, sometimes

The occurrence and pathogenicity of Serratospiculum tendo (Nematoda: Diplotriaenoidea) in birds of prey from southern Italy.

PubMed

Santoro, M; D'Alessio, N; Di Prisco, F; Kinsella, J M; Barca, L; Degli Uberti, B; Restucci, B; Martano, M; Troisi, S; Galiero, G; Veneziano, V

2016-05-01

The air sacs of free-ranging birds of prey (n= 652) from southern Italy, including 11 species of Accipitriformes and six of Falconiforms, were examined for infections with Serratospiculum tendo (Nematoda: Diplotriaenoidea). Of the 17 species of birds examined, 25 of 31 (80.6%) peregrine falcons (Falco peregrinus) from Calabria Region and a single northern goshawk (Accipiter gentilis) from Campania Region were infected with S. tendo, suggesting a strong host specificity for the peregrine falcon. The northern goshawk and 18 of 25 infected peregrine falcons showed cachexia and all infected birds had bone fractures. At gross examination, air sacculitis and pneumonia were the most common lesions in infected birds. Microscopically, the air-sac walls showed thickening of the smooth muscle cells, resulting in a papillary appearance, along with hyperplasia of the mesothelium and epithelium, and foci of plasma cell infiltration and macrophages associated with several embryonated eggs and adult parasites. Extensive areas of inflammation were found in the lungs, characterized by lymphocytes, macrophages and fibroblasts surrounding embryonated eggs. The northern goshawk also had detachment of the dextral lung with several necrotic foci. In this case, the death of the bird was directly attributed to S. tendo infection. Lesions and pathological changes observed here suggest that S. tendo can cause disease.

Eucoleus boehmi infection in red fox (Vulpes vulpes) from Italy.

PubMed

Veronesi, Fabrizia; Morganti, Giulia; di Cesare, Angela; Lepri, Elvio; Cassini, Rudi; Zanet, Stefania; Deni, Dario; Chiari, Mario; Ferroglio, Ezio

2014-12-15

In the last decade an increase of the number of red foxes in anthropized habitats across European countries, including Italy, has been observed. This pones implications in terms of disease transmission between wildlife and domestic animals; in fact, there are evidences of the role of foxes as reservoirs and amplifiers of a broad spectrum of parasites infecting pets. The present study evaluated the prevalence of Eucoleus boehmi, an emerging extra-intestinal nematodes of the Capillariinae subfamily, in red foxes. The nasal passages and sinuses of 179 red foxes culled from several areas of northern and central Italy were inspected and the mucosal surfaces were scrapped and examined for adult nematodes and eggs, microscopically and genetically identified. Overall 55 foxes (30.7%) were found to be infected with E. boehmi, i.e. 27 on inspection of the nasal passages and sinuses and 28 on mucosal flush and scraping. The occurrence of E. boehmi was significantly (p < 0.05) correlated to the sampling location, the age and gender of the animals examined; the higher rates of prevalence were observed in animals culled in Piedmont (43.3%) and in female (60.6%) and adult (38.1%) subjects. A total of 184 adult parasites were recovered, with a mean intensity of infection of 3.34, and a more frequent localization of E. boehmi in the nasal passages rather than in the sinuses. A significant (p < 0.05) relationship was found between the parasite burden and body condition and age of the animals; the intensity of infection was significantly higher in juveniles (mean: 6.3 specimens) and in animals showing poor fox body condition (mean: 7.8 specimens). These results show that E. boehmi is highly prevalent in the red fox populations of certain areas of Italy. Epidemiological implications are discussed, with a special focus on the role that this wild canid may have in the increasing transmission of nasal eucoleosis to domestic dogs. Copyright © 2014 Elsevier B.V. All rights reserved.

Molecular Evolution and Phylogeography of Co-circulating IHNV and VHSV in Italy

PubMed Central

Abbadi, Miriam; Fusaro, Alice; Ceolin, Chiara; Casarotto, Claudia; Quartesan, Rosita; Dalla Pozza, Manuela; Cattoli, Giovanni; Toffan, Anna; Holmes, Edward C.; Panzarin, Valentina

2016-01-01

Infectious haematopoietic necrosis virus (IHNV) and viral haemorrhagic septicaemia virus (VHSV) are the most important viral pathogens impacting rainbow trout farming. These viruses are persistent in Italy, where they are responsible for severe disease outbreaks (epizootics) that affect the profitability of the trout industry. Despite the importance of IHNV and VHSV, little is known about their evolution at a local scale, although this is likely to be important for virus eradication and control. To address this issue we performed a detailed molecular evolutionary and epidemiological analysis of IHNV and VHSV in trout farms from northern Italy. Full-length glycoprotein gene sequences of a selection of VHSV (n = 108) and IHNV (n = 89) strains were obtained. This revealed that Italian VHSV strains belong to sublineages Ia1 and Ia2 of genotype Ia and are distributed into 7 genetic clusters. In contrast, all Italian IHNV isolates fell within genogroup E, for which only a single genetic cluster was identified. More striking was that IHNV has evolved more rapidly than VHSV (mean rates of 11 and 7.3 × 10−4 nucleotide substitutions per site, per year, respectively), indicating that these viruses exhibit fundamentally different evolutionary dynamics. The time to the most recent common ancestor of both IHNV and VHSV was consistent with the first reports of these pathogens in Italy. By combining sequence data with epidemiological information it was possible to identify different patterns of virus spread among trout farms, in which adjacent facilities can be infected by either genetically similar or different viruses, and farms located in different water catchments can be infected by identical strains. Overall, these findings highlight the importance of combining molecular and epidemiological information to identify the determinants of IHN and VHS spread, and to provide data that is central to future surveillance strategies and possibly control. PMID:27602026

Molecular characterization and phylogenetic inferences of Dermanyssus gallinae isolates in Italy within an European framework.

PubMed

Marangi, M; Cantacessi, C; Sparagano, O A E; Camarda, A; Giangaspero, A

2014-12-01

In order to investigate the genetic relationships between Dermanyssus gallinae (Metastigmata: Dermanyssidae) (de Geer) isolates from poultry farms in Italy and other European countries, phylogenetic analysis was performed using a portion of the cytochrome c oxidase subunit 1 (cox1) gene of the mitochondrial DNA and the internal transcribed spacers (ITS1+5.8S+ITS2) of the ribosomal DNA. A total of 360 cox1 sequences and 360 ITS+ sequences were obtained from mites collected on 24 different poultry farms in 10 different regions of Northern and Southern Italy. Phylogenetic analysis of the cox1 sequences resulted in the clustering of two groups (A and B), whereas phylogenetic analysis of the ITS+ resulted in largely unresolved clusters. Knowledge of the genetic make-up of mite populations within countries, together with comparative analyses of D. gallinae isolates from different countries, will provide better understanding of the population dynamics of D. gallinae. This will also allow the identification of genetic markers of emerging acaricide resistance and the development of alternative strategies for the prevention and treatment of infestations. © 2014 The Royal Entomological Society.

Regional Landslide Mapping Aided by Automated Classification of SqueeSAR™ Time Series (Northern Apennines, Italy)

NASA Astrophysics Data System (ADS)

Iannacone, J.; Berti, M.; Allievi, J.; Del Conte, S.; Corsini, A.

2013-12-01

Space borne InSAR has proven to be very valuable for landslides detection. In particular, extremely slow landslides (Cruden and Varnes, 1996) can be now clearly identified, thanks to the millimetric precision reached by recent multi-interferometric algorithms. The typical approach in radar interpretation for landslides mapping is based on average annual velocity of the deformation which is calculated over the entire times series. The Hotspot and Cluster Analysis (Lu et al., 2012) and the PSI-based matrix approach (Cigna et al., 2013) are examples of landslides mapping techniques based on average annual velocities. However, slope movements can be affected by non-linear deformation trends, (i.e. reactivation of dormant landslides, deceleration due to natural or man-made slope stabilization, seasonal activity, etc). Therefore, analyzing deformation time series is crucial in order to fully characterize slope dynamics. While this is relatively simple to be carried out manually when dealing with small dataset, the time series analysis over regional scale dataset requires automated classification procedures. Berti et al. (2013) developed an automatic procedure for the analysis of InSAR time series based on a sequence of statistical tests. The analysis allows to classify the time series into six distinctive target trends (0=uncorrelated; 1=linear; 2=quadratic; 3=bilinear; 4=discontinuous without constant velocity; 5=discontinuous with change in velocity) which are likely to represent different slope processes. The analysis also provides a series of descriptive parameters which can be used to characterize the temporal changes of ground motion. All the classification algorithms were integrated into a Graphical User Interface called PSTime. We investigated an area of about 2000 km2 in the Northern Apennines of Italy by using SqueeSAR™ algorithm (Ferretti et al., 2011). Two Radarsat-1 data stack, comprising of 112 scenes in descending orbit and 124 scenes in ascending orbit

The Bologna Process in Italy

ERIC Educational Resources Information Center

Ballarino, Gabriele; Perotti, Loris

2012-01-01

Italy was among the promoters of the Bologna Process and the early adopters of the reform. If one looks at its impact on the formal structure of curricula and study programmes, the reform undertaken under the Bologna banner seems to have been one of the major educational reforms ever achieved in Italy. This article describes how the Bologna…

Epidemiological study of hazelnut bacterial blight in central Italy by using laboratory analysis and geostatistics.

PubMed

Lamichhane, Jay Ram; Fabi, Alfredo; Ridolfi, Roberto; Varvaro, Leonardo

2013-01-01

Incidence of Xanthomonas arboricola pv. corylina, the causal agent of hazelnut bacterial blight, was analyzed spatially in relation to the pedoclimatic factors. Hazelnut grown in twelve municipalities situated in the province of Viterbo, central Italy was studied. A consistent number of bacterial isolates were obtained from the infected tissues of hazelnut collected in three years (2010-2012). The isolates, characterized by phenotypic tests, did not show any difference among them. Spatial patterns of pedoclimatic data, analyzed by geostatistics showed a strong positive correlation of disease incidence with higher values of rainfall, thermal shock and soil nitrogen; a weak positive correlation with soil aluminium content and a strong negative correlation with the values of Mg/K ratio. No correlation of the disease incidence was found with soil pH. Disease incidence ranged from very low (<1%) to very high (almost 75%) across the orchards. Young plants (4-year old) were the most affected by the disease confirming a weak negative correlation of the disease incidence with plant age. Plant cultivars did not show any difference in susceptibility to the pathogen. Possible role of climate change on the epidemiology of the disease is discussed. Improved management practices are recommended for effective control of the disease.

Epidemiological Study of Hazelnut Bacterial Blight in Central Italy by Using Laboratory Analysis and Geostatistics

PubMed Central

Lamichhane, Jay Ram; Fabi, Alfredo; Ridolfi, Roberto; Varvaro, Leonardo

2013-01-01

Incidence of Xanthomonas arboricola pv. corylina, the causal agent of hazelnut bacterial blight, was analyzed spatially in relation to the pedoclimatic factors. Hazelnut grown in twelve municipalities situated in the province of Viterbo, central Italy was studied. A consistent number of bacterial isolates were obtained from the infected tissues of hazelnut collected in three years (2010–2012). The isolates, characterized by phenotypic tests, did not show any difference among them. Spatial patterns of pedoclimatic data, analyzed by geostatistics showed a strong positive correlation of disease incidence with higher values of rainfall, thermal shock and soil nitrogen; a weak positive correlation with soil aluminium content and a strong negative correlation with the values of Mg/K ratio. No correlation of the disease incidence was found with soil pH. Disease incidence ranged from very low (<1%) to very high (almost 75%) across the orchards. Young plants (4-year old) were the most affected by the disease confirming a weak negative correlation of the disease incidence with plant age. Plant cultivars did not show any difference in susceptibility to the pathogen. Possible role of climate change on the epidemiology of the disease is discussed. Improved management practices are recommended for effective control of the disease. PMID:23424654

OGS improvements in 2012 in running the Northeastern Italy Seismic Network: the Ferrara VBB borehole seismic station

NASA Astrophysics Data System (ADS)

Pesaresi, Damiano; Romanelli, Marco; Barnaba, Carla; Bragato, Pier Luigi; Durì, Giorgio

2013-04-01

The Centro di Ricerche Sismologiche (CRS, Seismological Research Center) of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale (OGS, Italian National Institute for Oceanography and Experimental Geophysics) in Udine (Italy) after the strong earthquake of magnitude M=6.4 occurred in 1976 in the Italian Friuli-Venezia Giulia region, started to operate the Northeastern Italy Seismic Network: it currently consists of 17 very sensitive broad band and 18 simpler short period seismic stations, all telemetered to and acquired in real time at the OGS-CRS data center in Udine. Real time data exchange agreements in place with other Italian, Slovenian, Austrian and Swiss seismological institutes lead to a total number of about 100 seismic stations acquired in real time, which makes the OGS the reference institute for seismic monitoring of Northeastern Italy. The southwestern edge of the OGS seismic network stands on the Po alluvial basin: earthquake localization and characterization in this area is affected by the presence of soft alluvial deposits. OGS ha already experience in running a local seismic network in high noise conditions making use of borehole installations in the case of the micro-seismicity monitoring of a local gas storage site for a private company. Following the ML=5.9 earthquake that struck the Emilia region around Ferrara in Northern Italy on May 20, 2012 at 02:03:53 UTC, a cooperation of Istituto Nazionale di Geofisica e Vulcanologia, OGS, the Comune di Ferrara and the University of Ferrara lead to the reinstallation of a previously existing very broad band (VBB) borehole seismic station in Ferrara. The aim of the OGS intervention was on one hand to extend its real time seismic monitoring capabilities toward South-West, including Ferrara and its surroundings, and on the other hand to evaluate the seismic response at the site. We will describe improvements in running the Northeastern Italy Seismic Network, including details of the Ferrara VBB

[Ten year cardio-cerebro-vascular mortality and morbidity in a Southern Italy cohort: the VIP Project data].

PubMed

Capuano, Vincenzo; Lamaida, Norman; Torre, Sergio; Capuano, Ernesto; Borrelli, Maria Immacolata; Capuano, Eduardo; Clarizia, Maria Maddalena; Capuano, Rocco; De Rosa, Carmela

2013-03-01

In Italy the mortality data were obtained almost exclusively from the data RENCAM (Name Causes of Death Register), while there are few prospective surveys. In order to assess whether there are particular epidemiological conditions in the geographical area of Mercato S. Severino, in Southern Italy, we have studied, and reassessed at ten years (1998/99 - 2008/09), a cohort of adult general population in a project of cardiovascular epidemiology and prevention. We calculated the rates of mortality and morbidity from cardiovascular events covering the period 1998/99 - 2008/09, in a cohort of 1200 persons (600 men and 600 women) aged 25 to 74 years. Data were standardized using the European standard population. Mortality from cardiovascular causes was 46.5% in men and 48.7% in women; it was mainly concentrated in the age group 65-74 years where it occurred on 62.9% of deaths in men and 66.7% in women. Regarding morbidity, the incidence of events to ten years of non-fatal myocardial infarction was 2.2% in men and of 1.8% in women. PTCA interventions to ten year have been 3.3% in men and 3.4% in women, the interventions of aorto-coronary bypass have been 2.4% and 0.5% for men and women respectively. While all major cardiovascular events have been more frequent in men, in women there was a higher incidence of stroke (1.6% vs 0.9%). Although by comparison with other European countries Italy is among the countries considered at low-risk of coronary heart disease, in Campania cardiovascular diseases reach higher rates than the rest of the country. Our results are in line with the literature data and confirm that cardiovascular diseases are a major public health problem. Local analysis to propose means to provide useful information for planning prevention interventions targeted to their own territory.

Extensive Field Survey, Laboratory and Greenhouse Studies Reveal Complex Nature of Pseudomonas syringae-Associated Hazelnut Decline in Central Italy

PubMed Central

Lamichhane, Jay Ram; Bartoli, Claudia; Varvaro, Leonardo

2016-01-01

Pseudomonas avellanae (Pav) has been reported as the causal agent of bacterial decline and bacterial canker of hazelnut in Italy and Greece, respectively. Both hazelnut diseases were reported to be similar in terms of symptoms, severity and persistence. In this study, we found that both symptomatic and asymptomatic trees in the field were colonized by Pav. Multilocus Sequence Typing (MLST) analysis showed that Pav strains isolated during this study in Italy belong to the P. syringae phylogroup 1 and they are closely related to Pav strains previously isolated in Greece from hazelnut bacterial canker. On the other hand, strains isolated in earlier studies from hazelnut decline in Italy belong to both phylogroup 1 and 2 of P. syringae. Both phylogroup 1 strains of P. syringae from Greece and Italy are different than strains isolated in this study in terms of their capacity to excrete fluorescent pigments on different media. Despite the same plant genotype and cropping practices adopted, the incidence of hazelnut decline ranged from nearly 0 to 91% across our study sites. No disease developed on plants inoculated with Pav through wounding while leaf scar inoculations produced only mild disease symptoms. Based on our results and the previously reported correlation between pedo-climatic conditions and hazelnut decline, we conclude that hazelnut decline in central Italy could be incited by a combination of predisposing (adverse pedo-climatic conditions) and contributing factors (Pav). Because this is a true decline different from “bacterial canker” described in Greece, we refer to it as hazelnut decline (HD). PMID:26840951

Extensive Field Survey, Laboratory and Greenhouse Studies Reveal Complex Nature of Pseudomonas syringae-Associated Hazelnut Decline in Central Italy.

PubMed

Lamichhane, Jay Ram; Bartoli, Claudia; Varvaro, Leonardo

2016-01-01

Pseudomonas avellanae (Pav) has been reported as the causal agent of bacterial decline and bacterial canker of hazelnut in Italy and Greece, respectively. Both hazelnut diseases were reported to be similar in terms of symptoms, severity and persistence. In this study, we found that both symptomatic and asymptomatic trees in the field were colonized by Pav. Multilocus Sequence Typing (MLST) analysis showed that Pav strains isolated during this study in Italy belong to the P. syringae phylogroup 1 and they are closely related to Pav strains previously isolated in Greece from hazelnut bacterial canker. On the other hand, strains isolated in earlier studies from hazelnut decline in Italy belong to both phylogroup 1 and 2 of P. syringae. Both phylogroup 1 strains of P. syringae from Greece and Italy are different than strains isolated in this study in terms of their capacity to excrete fluorescent pigments on different media. Despite the same plant genotype and cropping practices adopted, the incidence of hazelnut decline ranged from nearly 0 to 91% across our study sites. No disease developed on plants inoculated with Pav through wounding while leaf scar inoculations produced only mild disease symptoms. Based on our results and the previously reported correlation between pedo-climatic conditions and hazelnut decline, we conclude that hazelnut decline in central Italy could be incited by a combination of predisposing (adverse pedo-climatic conditions) and contributing factors (Pav). Because this is a true decline different from "bacterial canker" described in Greece, we refer to it as hazelnut decline (HD).

48 CFR 252.229-7003 - Tax Exemptions (Italy).

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Tax Exemptions (Italy... of Provisions And Clauses 252.229-7003 Tax Exemptions (Italy). As prescribed in 229.402-70(c), use the following clause: Tax Exemptions (Italy) (JAN 2002) (a) The Contractor represents that the...

Outbreak of type C botulism in birds and mammals in the Emilia Romagna region, northern Italy.

PubMed

Defilippo, Francesco; Luppi, Andrea; Maioli, Giulia; Marzi, Dario; Fontana, Maria Cristina; Paoli, Federica; Bonilauri, Paolo; Dottori, Michele; Merialdi, Giuseppe

2013-10-01

Over a 7-day period beginning 8 August 2011, a large number of wild birds of several species were found dead or with neurologic clinical signs along the shore of Crostolo stream, in the Emilia Romagna region, Italy. Twenty-eight Mallards (Anas platyrhynchos), two Hooded Crows (Corvus corone cornix), and three coypus (Myocastor coypus) were found moribund on the Crostolo stream bank, collected, and sent to Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia Romagna, Reggio Emilia Section. The cause of mortality was determined to be Clostridium botulinum type C toxin. The toxin was identified by a mouse bioassay for botulinum toxins and confirmed in bird sera and blowfly larvae (Lucilia caesar) collected from the stomachs of birds.

Mesothelioma among shipyard workers in Monfalcone, Italy

PubMed Central

Bianchi, Claudio; Bianchi, Tommaso

2012-01-01

Background: The high mesothelioma incidence in Monfalcone, Italy, is mainly attributable to shipbuilding activity. Mesothelioma risk among shipyard workers in Monfalcone is poorly defined. Materials and Methods: Workers hired at the Monfalcone shipyards in the period 1950-1959 were identified by surveying shipyard roll. The list of the workers was coupled with the archive data of Monfalcone and Trieste Hospitals. Mesotheliomas diagnosed in the above people were reexamined. Results: Of 1,403 workers hired in 1950-1959, 35 were diagnosed with mesothelioma (34 pleural, one peritoneal) between 1978 and 2012. Latency periods exceeded 40 years in 31 cases. The highest percentage of mesotheliomas was observed among people aged 14–19 years at hiring time (3.4%). Four mesothelioma patients had a blood relative with the same tumor. Conclusions: The present findings show high mesothelioma percentage among shipyard workers hired at young ages. The effects of asbestos exposure begun in 1950-1959 cannot be considered as exhausted. PMID:23776320

Religious slaughter in Italy.

PubMed

Cenci-Goga, B T; Mattiacci, C; De Angelis, G; Marini, P; Cuccurese, A; Rossi, R; Catanese, B

2010-06-01

This research aims to understand the prevalence of religious slaughter practices in Italy. Two different ways of slaughtering animals are identified. Conventional slaughter is performed with prior stunning; kosher slaughter is practiced without stunning. Halal slaughter is performed for most animals without stunning. Halal slaughter with prior stunning is acceptable for 5.90% of small ruminants. For Halal slaughter in Italy, the terms "religious slaughter with stunning" and "religious slaughter without stunning" should be used to differentiate religious slaughter practices, keeping animal welfare in perspective.

Nitrogen budget in a lowland coastal area within the Po River basin (northern Italy): multiple evidences of equilibrium between sources and internal sinks.

PubMed

Castaldelli, Giuseppe; Soana, Elisa; Racchetti, Erica; Pierobon, Enrica; Mastrocicco, Micol; Tesini, Enrico; Fano, Elisa Anna; Bartoli, Marco

2013-09-01

Detailed studies on pollutants genesis, path and transformation are needed in agricultural catchments facing coastal areas. Here, loss of nutrients should be minimized in order to protect valuable aquatic ecosystems from eutrophication phenomena. A soil system N budget was calculated for a lowland coastal area, the Po di Volano basin (Po River Delta, Northern Italy), characterized by extremely flat topography and fine soil texture and bordering a network of lagoon ecosystems. Main features of this area are the scarce relevance of livestock farming, the intense agriculture, mainly sustained by chemical fertilizers, and the developed network of artificial canals with long water residence time. Average nitrogen input exceeds output terms by ~60 kg N ha(-1) year(-1), a relatively small amount if compared to sub-basins of the same hydrological system. Analysis of dissolved inorganic nitrogen in groundwater suggests limited vertical loss and no accumulation of this element, while a nitrogen mass balance in surface waters indicates a net and significant removal within the watershed. Our data provide multiple evidences of efficient control of the nitrogen excess in this geographical area and we speculate that denitrification in soil and in the secondary drainage system performs this ecosystemic function. Additionally, the significant difference between nitrogen input and nitrogen output loads associated to the irrigation system, which is fed by the N-rich Po River, suggests that this basin metabolizes part of the nitrogen excess produced upstream. The traditionally absent livestock farming practices and consequent low use of manure as fertilizer pose the risk of excess soil mineralization and progressive loss of denitrification capacity in this area.

Work related injuries: estimating the incidence among illegally employed immigrants.

PubMed

Mastrangelo, Giuseppe; Rylander, Ragnar; Buja, Alessandra; Marangi, Gianluca; Fadda, Emanuela; Fedeli, Ugo; Cegolon, Luca

2010-12-08

Statistics on occupational accidents are based on data from registered employees. With the increasing number of immigrants employed illegally and/or without regular working visas in many developed countries, it is of interest to estimate the injury rate among such unregistered workers. The current study was conducted in an area of North-Eastern Italy. The sources of information employed in the present study were the Accidents and Emergencies records of a hospital; the population data on foreign-born residents in the hospital catchment area (Health Care District 4, Primary Care Trust 20, Province of Verona, Veneto Region, North-Eastern Italy); and the estimated proportion of illegally employed workers in representative samples from the Province of Verona and the Veneto Region. Of the 419 A&E records collected between January and December 2004 among non European Union (non-EU) immigrants, 146 aroused suspicion by reporting the home, rather than the workplace, as the site of the accident. These cases were the numerator of the rate. The number of illegally employed non-EU workers, denominator of the rate, was estimated according to different assumptions and ranged from between 537 to 1,338 individuals. The corresponding rates varied from 109.1 to 271.8 per 1,000 non-EU illegal employees, against 65 per 1,000 reported in Italy in 2004. The results of this study suggest that there is an unrecorded burden of illegally employed immigrants suffering from work related injuries. Additional efforts for prevention of injuries in the workplace are required to decrease this number. It can be concluded that the Italian National Institute for the Insurance of Work Related Injuries (INAIL) probably underestimates the incidence of these accidents in Italy.

Mitochondrial lineage sorting in action – historical biogeography of the Hyles euphorbiae complex (Sphingidae, Lepidoptera) in Italy

PubMed Central

2013-01-01

Background Mitochondrial genes are among the most commonly used markers in studies of species’ phylogeography and to draw conclusions about taxonomy. The Hyles euphorbiae complex (HEC) comprises six distinct mitochondrial lineages in the Mediterranean region, of which one exhibits a cryptic disjunct distribution. The predominant mitochondrial lineage in most of Europe, euphorbiae, is also present on Malta; however, it is nowadays strangely absent from Southern Italy and Sicily, where it is replaced by 'italica'. A separate biological entity in Italy is further corroborated by larval colour patterns with a congruent, confined suture zone along the Northern Apennines. By means of historic DNA extracted from museum specimens, we aimed to investigate the evolution of the mitochondrial demographic structure of the HEC in Italy and Malta throughout the Twentieth Century. Results At the beginning of the Twentieth Century, the European mainland lineages were also present at a moderate frequency in Southern Italy and Sicily. The proportion of 'italica' then steadily increased in this area from below 60 percent to near fixation in about 120 years. Thus, geographical sorting of mitochondrial lineages in the HEC was not as complete then as the current demography suggests. The pattern of an integral 'italica' core region and a disjunct euphorbiae distribution evolved very recently. To explain these strong demographic changes, we propose genetic drift due to anthropogenic habitat loss and fragmentation in combination with an impact from recent climate warming that favoured the spreading of the potentially better adapted 'italica' populations. Conclusions The pattern of geographically separated mitochondrial lineages is commonly interpreted as representing long term separated entities. However, our results indicate that such a pattern can emerge surprisingly quickly, even in a widespread and rather common taxon. We thus caution against drawing hasty taxonomic conclusions from

Hepatitis A virus strains circulating during 1997-2015 in Campania, a Southern Italy region with periodic outbreaks.

PubMed

Costantino, Angela; Coppola, Nicola; Spada, Enea; Bruni, Roberto; Taffon, Stefania; Equestre, Michele; Marcantonio, Cinzia; Sagnelli, Caterina; Dell'Isola, Chiara; Tosone, Grazia; Mascolo, Silvia; Sagnelli, Evangelista; Ciccaglione, Anna Rita

2017-11-01

In Italy, the incidence of hepatitis A has progressively declined over the last 30 years, though not homogeneously throughout the country. In Campania, Southern Italy, high annual incidence rates have been reported and several periodic outbreaks have occurred. To investigate the phylogenetic and epidemiologic relationships among HAV strains circulating in Campania over the period 1997-2015, 87 hepatitis A cases were investigated. The most frequent risk factor was the consumption of raw/undercooked shellfish (75/87, 86.2%). During 1997-2002 most viral strains were subtype IA (16/23, 70%); the phylogenetic pattern suggests that the incidence peaks observed in 2000-2001 had likely been caused by multiple strains. During a large 2004 outbreak, almost all viral variants were subtype IB (38/41, 93%); most of them (22/38, 58%) were recognized to be one of two main strains (differing for just a single nucleotide), the remaining sequences were strictly related variants. In 2014/2015, only IA strains were observed; two phylogenetically related but distinct strains were responsible, respectively, for a small cluster in 2014 and an outbreak in 2015. In each outbreak, several strains unrelated to those responsible for most cases were detected in a minority of patients, documenting a background of sporadic cases occurring even in the course of outbreaks; some of them proved to be identical to strains detected 11-14 years previously. Overall, the data suggest that several related and unrelated HAV strains have endemically circulated over the last 15 years in Campania, with some strains gaining epidemic transmission likely because of a local combination of multiple factors, including inadequate waste water purification and dietary habits. © 2017 Wiley Periodicals, Inc.

Soil organic carbon and land use in Veneto and Friuli Venezia Giulia (Northern Italy)

NASA Astrophysics Data System (ADS)

Francaviglia, Rosa; Renzi, Gianluca; Benedetti, Anna

2014-05-01

The Italian Ministry of Agricultural Food and Forestry Policies (MiPAAF) has set up a statistical survey aimed to provide the national forecast of yields and areas related to the main Italian agricultural crops (AGRIT). The methodology is based on field surveys and remote-sensed data, covers yearly the whole national territory, and is based on 100,000 observations which are statistically selected from a predefined grid made up of about 1,200,000 georeferenced points. In 2011-2012 we determined the soil organic carbon content (SOC) of 1,160 sampling points situated in Northern Italy in the plains and hills of Veneto (VEN) and Friuli Venezia Giulia (FVG), for which the land use in the period 2008-2010 was known. Samples have been subdivided in three main classes: arable crops, orchards and fodder crops. SOC was higher in FVG samples (2.48%, n=266) than in VEN samples (1.90%, n=894). The average value (2.03%) is clearly affected by the higher number of VEN samples. FVG data have been aggregated in continuous crops (maize, soybean, wheat), 2-yr rotations (maize-wheat, soybean wheat, maize-soybean), 3-yr rotations, vineyards (totally, partially and no-grassed), alfalfa, and permanent fodder crops. No significant differences were detected among the land uses due to the low number of samples in some classes, but some important findings do exist from the agronomic point of view. Fodder crops (5.65%), alfalfa (3.41%) and vineyards (2.72%) showed the higher SOC content. SOC was 2.94% and 1.39 % in the grassed and no-grassed vineyards respectively. In the arable crops the average SOC was 2.18%, ranging from 2.32% (soybean-wheat rotation) to 2.03% (continuous soybean). SOC was 2.19% in the continuous maize, with 2.23% in corn and 1.87% in silage maize. The lower values were in the maize-wheat rotation (1.53%) and the continuous wheat (1.47%). VEN data have been aggregated in continuous crops (maize, soybean and wheat), 2-yr rotations (maize-wheat, soybean-wheat, maize

Late Glacial to Holocene environmental variabilities: A new multi-proxy paleolimnological study of sedimentary sequences from Como (northern Italy)

NASA Astrophysics Data System (ADS)

Höbig, N.; Martinelli, E.; Motella, S.; Michetti, A. M.; Livio, F.; Tinner, W.; Reicherter, K.; Castelletti, L.

2012-04-01

Lake Como (northern Italy) is the deepest Italian lake, reaching a depth of about 425 m. The lambda-shaped lake expands about 45 km in NE-SW direction. Southwards of the hydrologically closed western branch, two sediment cores of 70 m (S1) and 65 m length (S2) were taken in the year 2005 close to the cathedral of Como (Piazza Verdi). The drilling sites are located in the middle of the Southern Alps, some 300 m from the present-day lakeshore. The cores provide the first detailed Late Glacial to Holocene multi-proxy record for the Lake Como basin. Our research is aimed at investigating the environmental and geological evolution of the Insubria Region. The multi-proxy study of the stratigraphic sequences contain geophysical, geotechnical, sedimentological, paleobotanical, and radiocarbon analyses. They have been performed for core S1 and are still in progress on core S2. With this data the working group focuses on two main issues. The first topic is the reconstruction of the natural and anthropogenic processes controlling the ground subsidence in the Como urban area (e.g., Comerci et al., 2007) and another aim is to reconstruct vegetation and land-use dynamics. In particular, 150 samples of vegetal macroremains have been collected in the palustrine deposits along S1 core, down to 31,00 m. Below this depth (dated 14C 12,496 ± 55 yr BP - 15,050 - 14,250 cal yr BP), the amount of plant macroremains in the sediment drops dramatically. The taxonomic determination was carried out on more than 800 macroremains. They are represented by fragments of wood, leaves, needles, seeds, fruits, mosses and tiny charcoals (Motella, 2009, unpublished PhD Thesis). Picea/Larix, Pinus sp., Juniperus with Betula, found in the deeper levels (30.80 - 30.00 m), are the first arboreal taxa that colonized the shores of Lake Como, and show that the reforestation began in this area about 16,000 years ago. During the early Holocene (25.10 m) Abies alba expanded and further upwards the sequence

A nationwide genetic testing survey in Italy, year 2007.

PubMed

Dallapiccola, Bruno; Torrente, Isabella; Agolini, Emanuele; Morena, Arnaldo; Mingarelli, Rita

2010-02-01

The aim of this study was to collect the practices of cytogenetic and molecular genetic testing and genetic counseling activities in Italy in the year 2007 and provide guidance to the national and regional health systems to improve the organization of genetic services. A web-based survey was carried out to assess the total number and the type of analyses, the number and type of genetic counseling sessions, and the personnel attending these activities. The quality management system of the responding structures, in terms of certification and accreditation standards, was also investigated. The appropriateness of requests for genetic testing was evaluated for six disorders. Data were collected from 278 responding centers, half of which were located in the northern regions of the country. Twenty-eight percent of the total were certified according to quality standards. A total of 217 molecular genetic and 171 cytogenetic laboratories, and 102 clinical genetic services were surveyed. About 560,000 genetic tests, including 311,069 cytogenetic and 248,691 molecular genetic analyses of 556 genes, were recorded. The fetal karyotype was examined on either trophoblast or amniocytes in about one of every 4.4 pregnancies. Only 11.5% of cytogenetic analyses and 13.5% of molecular tests were accompanied by genetic counseling. Concerning the appropriateness of a request for genetic testing, a low congruity was found between the clinical diagnosis and the laboratory results. This study highlights the need for reorganizing the genetic structure network in Italy, which at present is oversized, improving the quality management systems, expanding the availability of testing for rare disease genes, and improving access to pretest and posttest genetic counseling.

Kinematic analysis of recent and active faults of the southern Umbria-Marche domain, Northern Apennines, Italy: geological constraints to geodynamic models

NASA Astrophysics Data System (ADS)

Pasqui, Valeria; Viti, Marcello; Mantovani, Enzo

2013-04-01

The recent and active deformation that affects the crest zone of the Umbria-Marche belt (Northern Apennines, Italy) displays a remarkable extensional character, outlined by development of normal fault sets that overprint pre-existing folds and thrusts of Late Miocene-Early Pliocene age. The main extensional fault systems often bound intermontane depressions hosting recent, mainly continental, i.e. fluvial or lacustrine deposits, separating the latter from Triassic-Miocene, mainly carbonatic and siliciclastic marine rocks that belong to the Romagna-Umbria-Marche stratigraphic succession. Stratigraphic data indicate that the extensional strain responsible for the development of normal fault-bounded continental basins in the outer zones of the Northern Apennines was active until Middle Pleistocene time. Since Middle Pleistocene time onwards a major geodynamic change has affected the Central Mediterranean region, with local reorganization of the kinematics in the Adria domain and adjacent Apennine belt. A wide literature illustrates that the overall deformation field of the Central Mediterranean area is presently governed by the relative movements between the Eurasia and Africa plates. The complex interaction of the Africa-Adria and the Anatolian-Aegean-Balkan domains has led the Adria microplate to migrate NW-ward and to collide against Eurasia along the Eastern Southern Alps. As a consequence Adria is presently moving with a general left-lateral displacement with respect to the Apennine mountain belt. The sinistral component of active deformations is also supported by analysis of earthquake focal mechanisms. A comparison between geophysical and geological evidence outlines an apparent discrepancy: most recognized recent and active faults display a remarkable extensional character, as shown by the geometry of continental basin-bounding structutes, whereas geodetic and seismologic evidence indicates the persistency of an active strike-slip, left-lateral dominated

International patterns and trends in testicular cancer incidence, overall and by histologic subtype, 1973-2007.

PubMed

Trabert, B; Chen, J; Devesa, S S; Bray, F; McGlynn, K A

2015-01-01

Incidence rates of testicular cancer in Northern European and North American countries have been widely reported, whereas rates in other populations, such as Eastern Europe, Central/South America, Asia, and Africa, have been less frequently evaluated. We examined testicular cancer incidence rates overall and by histologic type by calendar time and birth cohort for selected global populations 1973-2007. Age-standardized incidence rates over succeeding 5-year periods were calculated from volumes 4-9 of Cancer Incidence in Five Continents electronic database (CI5plus) and the newly released CI5X (volume 10) database. Annual percent change over the 35-year period was calculated using weighted least squares regression. Age-period-cohort analyses were performed and observed rates and fitted rate ratios presented by birth cohort. Incidence rates of testicular cancer increased between 1973-1977 and 2003-2007 in most populations evaluated worldwide. Of note, incidence rates in Eastern European countries rose rapidly and approached rates in Northern European countries. Rates in Central and South America also increased and are now intermediate to the high rates among men of European ancestry and low rates among men of Asian or African descent. Some heterogeneity in the trends in seminoma and nonseminoma were observed in Denmark, the United Kingdom, and among US whites, particularly in recent generations, with rapid and uniform increases in the incidence of both histologic types in Slovakia. Reasons for the rising incidence rates among European and American populations remain unexplained; however, changing distributions in the prevalence of risk factors for testicular cancer cannot be ruled out. © 2014 American Society of Andrology and European Academy of Andrology.

Prostate cancer incidence and tumor severity in Georgia: descriptive epidemiology, racial disparity, and geographic trends.

PubMed

Wagner, Sara E; Bauer, Sarah E; Bayakly, A Rana; Vena, John E

2013-01-01

Limited research has been conducted to describe the geographical clustering and distribution of prostate cancer (PrCA) incidence in Georgia (GA). This study describes and compares the temporal and geographic trends of PrCA incidence in GA with a specific focus on racial disparities. GA Comprehensive Cancer Registry PrCA incidence data were obtained for 1998-2008. Directly standardized age-adjusted PrCA incidence rates per 100,000 were analyzed by race, stage, grade, and county. County-level hotspots of PrCA incidence were analyzed with the Getis-Ord Gi* statistic in a geographic information system; a census tract-level cluster analysis was performed with a Discrete Poisson model and implemented in SaTScan(®) software. Significant (p < 0.05) hotspots of PrCA incidence were observed in nine southwestern counties and six centrally located counties among men of both races. Six significant (p < 0.1) clusters of PrCA incidence rates were detected for men of both races in north and northwest central Georgia. When stratified by race, clusters among white and black men were similar, although centroids were slightly shifted. Most notably, a large (122 km radius) cluster in northwest central Georgia was detected only in whites, and two smaller clusters (0-32 km radii) were detected in Southwest Georgia only in black men. Clusters of high-grade and late-stage tumors were identified primarily in the northern portion of the state among men of both races. This study revealed a pattern of higher incidence and more advanced disease in northern and northwest central Georgia, highlighting geographic patterns that need more research and investigation of possible environmental determinants.

OGS improvements in 2012 in running the North-eastern Italy Seismic Network: the Ferrara VBB borehole seismic station

NASA Astrophysics Data System (ADS)

Pesaresi, D.; Romanelli, M.; Barnaba, C.; Bragato, P. L.; Durì, G.

2014-07-01

The Centro di Ricerche Sismologiche (CRS, Seismological Research Centre) of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale (OGS, Italian National Institute for Oceanography and Experimental Geophysics) in Udine (Italy) after the strong earthquake of magnitude M=6.4 occurred in 1976 in the Italian Friuli-Venezia Giulia region, started to operate the North-eastern Italy Seismic Network: it currently consists of 17 very sensitive broad band and 18 simpler short period seismic stations, all telemetered to and acquired in real time at the OGS-CRS data centre in Udine. Real time data exchange agreements in place with other Italian, Slovenian, Austrian and Swiss seismological institutes lead to a total number of about 100 seismic stations acquired in real time, which makes the OGS the reference institute for seismic monitoring of North-eastern Italy. The south-western edge of the OGS seismic network (Fig. 1) stands on the Po alluvial basin: earthquake localization and characterization in this area is affected by the presence of soft alluvial deposits. OGS ha already experience in running a local seismic network in high noise conditions making use of borehole installations in the case of the micro-seismicity monitoring of a local gas storage site for a private company. Following the ML = 5.9 earthquake that struck the Emilia region around Ferrara in Northern Italy on 20 May 2012 at 02:03:53 UTC, a cooperation of Istituto Nazionale di Geofisica e Vulcanologia, OGS, the Comune di Ferrara and the University of Ferrara lead to the reinstallation of a previously existing very broad band (VBB) borehole seismic station in Ferrara. The aim of the OGS intervention was on one hand to extend its real time seismic monitoring capabilities toward South-West, including Ferrara and its surroundings, and on the other hand to evaluate the seismic response at the site. We will describe improvements in running the North-eastern Italy Seismic Network, including details of

Group Psychotherapy in Italy.

PubMed

Giannone, Francesca; Giordano, Cecilia; Di Blasi, Maria

2015-10-01

This article describes the history and the prevailing orientations of group psychotherapy in Italy (psychoanalytically oriented, psychodrama, CBT groups) and particularly group analysis. Provided free of charge by the Italian health system, group psychotherapy is growing, but its expansion is patchy. The main pathways of Italian training in the different group psychotherapy orientations are also presented. Clinical-theoretical elaboration on self development, psychopathology related to group experiences, and the methodological attention paid to objectives and methods in different clinical groups are issues related to group therapy in Italy. Difficulties in the relationship between research and clinical practice are discussed, as well as the empirical research network that tries to bridge the gap between research and clinical work in group psychotherapy. The economic crisis in Italy has led to massive cuts in health care and to an increasing demand for some forms of psychological treatment. For these reasons, and because of its positive cost-benefit ratio, group psychotherapy is now considered an important tool in the national health care system to expand the clinical response to different forms of psychological distress.

Tomographic models and seismotectonics of the Reggio Emilia region, Italy

NASA Astrophysics Data System (ADS)

Ciaccio, M. G.; Chiarabba, C.

2002-02-01

The aim of this study is to define the Vp and Vp/Vs structure of the fault zone ruptured by the M L 5.1 earthquake of October 15, 1996 which occurred near Reggio Emilia (central-northern Italy). A 1-month-long seismic sequence followed the mainshock and occurred in a small region along the outer border of the northern Apenninic belt, at depth ranging between 10 and 17 km. P- and S-wave arrival times from 304 aftershocks recorded by two local dense seismic arrays installed in the epicentral region have been inverted to obtain one- and three-dimensional velocity models by using state of the art local earthquake tomographic techniques. Velocity models and aftershock relocation help us to infer the seismotectonic of the region. Earthquakes originated along a NW-dipping backthrust of a NE-trending main thrust, composing the western part of the broad Ferrara Arc. A main high Vp and high Vp/Vs region delineates a pop-up structure in the center of the area. The high Vp/Vs within the pop-up structure supports the presence of a zone with increased pore pressure. The hypocentral depth of both mainshock and aftershocks is greater than those usually found for the main seismogenic regions of the Apenninic belt. P-wave velocity values in the seismogenic area, obtained by tomography, are compatible with rocks of the Mesozoic cover and suggest that seismicity occurred within the Mesozoic units stack at present by compressional tectonics.

Chrysotile asbestos quantification in serpentinite quarries: a case study in Valmalenco, central Alps, northern Italy

NASA Astrophysics Data System (ADS)

Cavallo, Alessandro

2013-04-01

Outcrops of serpentinites are usually strongly fractured and cataclastic, and the rock can only be used as ballast. However, in rare cases, like in Valmalenco (Central Alps, Northern Italy), fractures are regular and well spaced, and the rock mass has good geotechnical quality, ideal conditions for the extraction of dimension stone blocks. The Valmalenco Serpentinite is marketed worldwide as dimension and decorative stone, with remarkable mechanical properties and pleasing colours and textures. However, the same area was once subject to chrysotile asbestos mining, in the form of discrete veins along the main discontinuities of the rock mass. For this reason, airborne asbestos contamination can occur during the extraction and processing cycle of the rocks, therefore it is essential to locate and quantify asbestos in the rock mass, to reduce as much as possible the exposure risk. The first step was a detailed geostructural survey of each quarry, in order to characterize the main discontinuities (orientation, spacing, linear persistence, opening, filling), with special attention to the identification of fibrous minerals. The surveys was followed by extensive sampling of massive rocks, mineralized veins and fillings of fractures, and the cutting sludge derived from diamond wire cutting. Preliminary qualitative XRPD was performed on all samples, while quantitative analysis was carried out on the most representative samples of the main rock mass discontinuities. On the other hand, XRPD is not effective in the identification of asbestos percentages of less than 2% by weight, and the accurate distinction among the various serpentine polymorphs (antigorite, lizardite, chrysotile) is very difficult (if not impossible) when they are simultaneously present, due to their very similar basic structure and the strong structural disorder. The same samples were then analyzed by SEM-EDS (fiber counting after filtration on a polycarbonate filter), for a better distinction between

Persistency of rupture directivity in moderate-magnitude earthquakes in Italy: Implications for seismic hazard

NASA Astrophysics Data System (ADS)

Rovelli, A.; Calderoni, G.

2012-12-01

A simple method based on the EGF deconvolution in the frequency domain is applied to detect the occurrence of unilateral ruptures in recent damaging earthquakes in Italy. The spectral ratio between event pairs with different magnitudes at individual stations shows large azimuthal variations above corner frequency when the target event is affected by source directivity and the EGF is not or vice versa. The analysis is applied to seismograms and accelerograms recorded during the seismic sequence following the 20 May 2012, Mw 5.6 main shock in Emilia, northern Italy, the 6 April 2009, Mw 6.1 earthquake of L'Aquila, central Italy, and the 26 September 1997, Mw 5.7 and 6.0 shocks in Umbria-Marche, central Italy. Events of each seismic sequence are selected as having consistent focal mechanisms, and the station selection obeys to the constraint of a similar source-to-receiver path for the event pairs. The analyzed data set of L'Aquila consists of 962 broad-band seismograms relative to 69 normal-faulting earthquakes (3.3 ≤ MW ≤ 6.1, according to Herrmann et al., 2011), stations are selected in the distance range 100 to 250 km to minimize differences in propagation paths. The seismogram analysis reveals that a strong along-strike (toward SE) source directivity characterized all of the three Mw > 5.0 shocks. Source directivity was also persistent up to the smallest magnitudes: 65% of earthquakes under study showed evidence of directivity toward SE whereas only one (Mw 3.7) event showed directivity in the opposite direction. Also the Mw 5.6 main shock of the 20 May 2012 in Emilia result in large azimuthal spectral variations indicating unilateral rupture propagation toward SE. According to the reconstructed geometry of the trust-fault plane, the inferred directivity direction suggests top-down rupture propagation. The analysis over the Emilia aftershock sequence is in progress. The third seismic sequence, dated 1997-1998, occurred in the northern Apennines and, similarly

Chromosomal heterozygosity and fertility in house mice (Mus musculus domesticus) from Northern Italy.

PubMed

Hauffe, H C; Searle, J B

1998-11-01

Following the discovery of over 40 Robertsonian (Rb) races of Mus musculus domesticus in Europe and North Africa, the house mouse has been studied extensively as an ideal model to determine the chromosomal changes that may cause or accompany speciation. Current models of chromosomal speciation are based on the assumption that heterozygous individuals have a particularly low fertility, although recent studies indicate otherwise. Despite their importance, fertility estimates for the house mouse are incomplete because traditional measurements, such as anaphase I nondisjunction and germ cell death, are rarely estimated in conjunction with litter size. In an attempt to bridge this gap, we have taken advantage of the house mouse hybrid zone in Upper Valtellina (Lombardy, Italy) in which five Rb races interbreed. We present data on the fertility of naturally occurring ("wild-caught") hybrids and of offspring from laboratory crosses of wild-caught mice ("laboratory-reared"), using various measurements. Wild-caught mice heterozygous for one fusion were more infertile than predicted from past studies, possibly due to genic hybridity; laboratory-reared heterozygotes carrying seven or eight trivalents at meiosis I and heterozygotes carrying one pentavalent also had low fertilities. These low fertilities are especially significant given the probable occurrence of a reinforcement event in Upper Valtellina.

An Outbreak of Japanese Encephalitis in Adults in Northern China, 2013: A Population-Based Study.

PubMed

Li, Xiaolong; Gao, Xiaoyan; Fu, Shihong; Wang, Huanyu; Lu, Zhi; He, Ying; Lei, Wenwen; Liang, Guodong

2018-05-09

A Japanese encephalitis (JE) epidemic occurred in 2013 in China. The aim of this study was to determine the spatial-temporal pattern of JE cases in adults occurring in 2013, as well as identify potential hotspots of incidences in the afflicted regions in China. To generate a spatial-temporal pattern of JE cases in China, epidemiological and demographic data between 2011 and 2013 were collected. Our results indicate that the total number of JE cases in 2013 was significantly higher compared with those in 2011 and 2012. While the incidence of JE in individuals aged less than 15 years decreased in 2013, the incidence rate increased substantially in those aged 15 years and older. The population aged over 40 years was associated with the greatest increase of JE. Demographic analysis revealed a consistent increase in the proportion of JE cases aged 15 years and older in 2013 (42%) compared with that in 2012 (15%). In addition, JE cases from areas located between 35°N, 114°E and 40°N, 120°E in northern China were found to account for 27.17% of total JE cases nationwide in 2013, compared with 2.21% and 3.13% in 2011 and 2012, respectively. In these northern regions, the group aged 15 years and older represents the predominant population with JE, accounting for 73% of total cases. Further cluster analysis identified a large number of hotspots of JE in adults (>15 years of age) in northern China. Unlike the JE epidemics primarily in children below 15 years old in southern China, a significant outbreak of JE occurred in northern China in 2013, with the older age groups being the primary population affected. The increasing incidence of JE in adults has become an important public health issue and poses a new challenge to the successful prevention and control of JE in China, as well as other countries in East Asia.

Post-incident monitoring to evaluate environmental damage from shipping incidents: chemical and biological assessments.

PubMed

Radović, Jagoš R; Rial, Diego; Lyons, Brett P; Harman, Christopher; Viñas, Lucia; Beiras, Ricardo; Readman, James W; Thomas, Kevin V; Bayona, Josep M

2012-10-30

Oil and chemical spills in the marine environment are an issue of growing concern. Oil exploration and exploitation is moving from the continental shelf to deeper waters, and to northern latitudes where the risk of an oil spill is potentially greater and may affect pristine ecosystems. Moreover, a growing number of chemical products are transported by sea and maritime incidents of hazardous and noxious substances (HNS) are expected to increase. Consequently, it seems timely to review all of the experience gained from past spills to be able to cope with appropriate response and mitigation strategies to combat future incidents. Accordingly, this overview is focused on the dissemination of the most successful approaches to both detect and assess accidental releases using chemical as well as biological approaches for spills of either oil or HNS in the marine environment. Aerial surveillance, sampling techniques for water, suspended particles, sediments and biota are reviewed. Early warning bioassays and biomarkers to assess spills are also presented. Finally, research needs and gaps in knowledge are discussed. Copyright © 2012 Elsevier Ltd. All rights reserved.

Epidemic characteristics and spatio-temporal patterns of scrub typhus during 2006-2013 in Tai'an, Northern China.

PubMed

Zheng, L; Yang, H-L; Bi, Z-W; Kou, Z-Q; Zhang, L-Y; Zhang, A-H; Yang, L; Zhao, Z-T

2015-08-01

Tai'an, a famous cultural tourist district, is a new endemic foci of scrub typhus in northern China. Frequent reports of travel-acquired cases and absence of effective vaccine indicated a significant health problem of scrub typhus in Tai'an. Thus, descriptive epidemiological methods and spatial-temporal scan statistics were used to describe the epidemic characteristics and detect the significant clusters of the high incidence of scrub typhus at the town level in Tai'an. Results of descriptive epidemiological analysis showed a total of 490 cases were reported in Tai'an with the annual average incidence ranging from 0·48 to 2·27/100 000 during 2006-2013. Females, the elderly and farmers are the high-risk groups. Monthly changes of scrub typhus cases indicated an obvious epidemic period in autumn. Spatial-temporal distribution analysis, showed significant clusters of high incidence mainly located in eastern and northern Tai'an. Our study suggests that more effective, targeted measures for local residents should be implemented in the eastern and northern areas of Tai'an in autumn. Meanwhile, it may prove beneficial for health policy makers to advise travellers to take preventive measures in order to minimize the risk of infection of scrub typhus in Tai'an.

Foresters' perceptions of windthrow dynamics in northern Minnesota riparian management zones

Treesearch

Jeremy C. Steil; Charles R. Blinn; Randy Kolka

2009-01-01

A survey was mailed to foresters in northern Minnesota to identify their perceptions of what conditions result in higher incidence of windthrow in riparian management zones (RMZ) where the upland has been clearcut. Results indicate that foresters think many variables impact windthrow, often interacting in complex ways. Foresters considered topographic exposure, species...

Unraveling Landscape Complexity: Land Use/Land Cover Changes and Landscape Pattern Dynamics (1954-2008) in Contrasting Peri-Urban and Agro-Forest Regions of Northern Italy.

PubMed

Smiraglia, D; Ceccarelli, T; Bajocco, S; Perini, L; Salvati, L

2015-10-01

This study implements an exploratory data analysis of landscape metrics and a change detection analysis of land use and population density to assess landscape dynamics (1954-2008) in two physiographic zones (plain and hilly-mountain area) of Emilia Romagna, northern Italy. The two areas are characterized by different landscape types: a mixed urban-rural landscape dominated by arable land and peri-urban settlements in the plain and a traditional agro-forest landscape in the hilly-mountain area with deciduous and conifer forests, scrublands, meadows, and crop mosaic. Urbanization and, to a lesser extent, agricultural intensification were identified as the processes underlying landscape change in the plain. Land abandonment determining natural forestation and re-forestation driven by man was identified as the process of change most representative of the hilly-mountain area. Trends in landscape metrics indicate a shift toward more fragmented and convoluted patterns in both areas. Number of patches, the interspersion and juxtaposition index, and the large patch index are the metrics discriminating the two areas in terms of landscape patterns in 1954. In 2008, mean patch size, edge density, interspersion and juxtaposition index, and mean Euclidean nearest neighbor distance were the metrics with the most different spatial patterns in the two areas. The exploratory data analysis of landscape metrics contributed to link changes over time in both landscape composition and configuration providing a comprehensive picture of landscape transformations in a wealthy European region. Evidence from this study are hoped to inform sustainable land management designed for homogeneous landscape units in similar socioeconomic contexts.

Economic evaluation of intravenous iodinated contrast media in Italy.

PubMed

Iannazzo, Sergio; Vandekerckhove, Stijn; De Francesco, Maria; Nayak, Akash; Ronco, Claudio; Morana, Giovanni; Valentino, Massimo

2014-01-01

Contrast-induced acute kidney injury (CI-AKI) is defined as a deterioration in renal function after administration of radiologic iodinated contrast media (CM). Iodixanol, showed a lower CI-AKI incidence than low-osmolar contrast media (LOCM). A cost-effectiveness analysis was performed comparing iodixanol and LOCM in intravenous (IV) setting in Italy. A Markov model was developed. Patients moved across four health states: CI-AKI free, CI-AKI, myocardial infarction, and death. The simulation horizon was lifetime with 1-month cycles. Costs and outcomes were discounted at 3.5 percent rate. CI-AKI incidence was considered from published literature across different definitions. Cost-effectiveness of iodixanol was assessed in terms of incremental cost per life-year gained. Net monetary benefit (NMB) was also calculated. Both deterministic and probabilistic sensitivity analyses were performed. Base-case results showed an average survival increase of 0.51 life-years and a savings of €7.25 for iodixanol versus LOCM. The cost-effectiveness of iodixanol was confirmed when other scenarios were explored, such as varying CI-AKI definition, sub-populations with specified risk factors, CM hospital bids prices, and inclusion of adverse drug reactions of allergic nature. An NMB ranging between €6,007.25 and €30,007.25 was calculated. Base-case results show that IV iodixanol is cost-effective compared with LOCM in the Italian clinical setting of a hospital computed tomography radiology practice. However, some caution is due, mainly linked to inherent limitations of the modeling technique and to the lack of agreement on CI-AKI incidence data in the clinical literature.

The impact of landslides on urban areas and infrastructure in Italy

NASA Astrophysics Data System (ADS)

Trigila, Alessandro; Spizzichino, Daniele; Iadanza, Carla

2010-05-01

Landslide risk in Italy is particularly high since in addition to the geological, geomorphological, seismic and structural settings which render it susceptible to frequent and widespread landslide phenomena, the Italian territory is also densely populated and highly urbanized. In terms of landslide hazard, 485,004 landslides occurred between A.D. 1116 and 2006 within Italy, with a landslide area of 20,721 km2 equal to 6.9% of the national territory. 5,708 municipal districts are affected by landslides (70.5% of the total), of which 2,940 with extremely high levels of criticality due to landslides affecting urban centres. This data emerges from the IFFI Project (Italian Landslide Inventory) which, set up by ISPRA - Institute for Environmental Protection and Research/Geological Survey of Italy and the Regions and self-governing Provinces, identifies landslide phenomena across Italy in accordance with standardized methods of data collection, recording and mapping. With regard to exposure and vulnerability, urban areas in Italy account for 17,929 km2, equal to 5.9% of the national territory. In the past 50 years, urban areas in Italy underwent a dramatic increase, whose surface has more than doubled. Often building areas did not benefit from any form of proper land use planning and management or detailed landslide hazard assessment. Moreover unauthorized building has reached levels as high as 60% in regions of Southern Italy. This study assesses the incidence of landslide phenomena and their impacts within urban areas of Italian provincial capitals in terms of number of landslides, surface area and type of movement. The people exposed to landslide risk at national level and critical points along highways, railways and road network has been also estimated. Landslides have been classified in two main categories: rapid and slow movements. The rapid phenomena are strictly correlated to the people safety, while the slow ones concern mainly losses and usability of buildings

Integrated care of muscular dystrophies in Italy. Part 2. Psychological treatments, social and welfare support, and financial costs.

PubMed

Magliano, Lorenza; Scutifero, Marianna; Patalano, Melania; Sagliocchi, Alessandra; Zaccaro, Antonella; Civati, Federica; Brighina, Erika; Vita, Gianluca; Messina, Sonia; Sframeli, Maria; Lombardo, Maria Elena; Scalise, Roberta; Colia, Giulia; Catteruccia, Maria; Berardinelli, Angela; Motta, Maria Chiara; Gaiani, Alessandra; Semplicini, Claudio; Bello, Luca; Astrea, Guja; Ricci, Giulia; D'Angelo, Maria Grazia; Vita, Giuseppe; Pane, Marika; D'Amico, Adele; Balottin, Umberto; Angelini, Corrado; Battini, Roberta; Politano, Luisa

2017-06-01

This paper describes the psycho-social treatments received by 502 patients with MDs and their relatives, and the costs for care sustained by the families in the previous six month period. Data were collected by the MD-Care Schedule (MD-CS) and the Family Problems Questionnaire (FPQ). Psycho-educational interventions were provided to 72 patients (14.3%), and social/welfare support to 331 patients (65.9%). Social/welfare support was higher in patients with DMD or LGMD, in those showing more severe disability, and in patients who were in contact with centres located in Northern Italy. Psycho-educational interventions were received by 156 (31%) relatives, and social/welfare support by 55 (10.9%) and mainly provided by Family/Patients Associations (83.6%). Relatives with higher educational levels, who spent more daily hours in the assistance of patients with DMD, and in contact with centres in Central Italy more frequently benefited from psycho-educational interventions. In the previous year, costs for care were sustained by 314 (63.9%) relatives. Financial difficulties related to patient's condition, were higher in families of patients who needed more intensive rehabilitation and daily hours of caregiving, and in families who lived further away from the reference's centre. These results showed that psycho-social aspects of MDs care are only partially met in Italy, and that ad hoc supportive interventions for these patients and their families should be potentiated.

Hepatitis A in Puglia (South Italy) after 10 years of universal vaccination: need for strict monitoring and catch-up vaccination

PubMed Central

2012-01-01

Background Raw seafood consumption was identified as the major risk factor for hepatitis A during the large epidemic of 1996 and 1997 in Puglia (South Italy). In Puglia, vaccination for toddlers and preadolescents has been recommended since 1998. The aim of the study was to evaluate the incidence, seroprevalence, molecular epidemiology, and environmental circulation of hepatitis A virus (HAV) in Puglia more than ten years after the introduction of anti-HAV vaccination in the regional immunization program. Methods Data on the incidence of acute hepatitis A in Puglia were analyzed. Characteristics and risk factors of 97 acute hepatitis A cases occurring in 2008–2009 were analyzed. Serum samples from 868 individuals aged 0 to 40 years were tested for anti-HAV antibodies. Fecal samples from 49 hepatitis A cases were analyzed by sequence analysis in the VP1/P2A region. In 2008, 203 mussel samples and 202 water samples from artesian wells were tested for HAV-RNA. Results Between 1998 and 2009, the incidence of acute hepatitis A declined from 14.8 to 0.8 per 100,000. The most frequent risk factors reported by cases in 2008–2009 were shellfish consumption (85%) and travel outside of Puglia or Italy (26%). Seroepidemiologic survey revealed high susceptibility to HAV in children and adults up to age 30 (65%-70%). None of the mussel or water samples were HAV-positive. Phylogenetic analysis revealed co-circulation of subtypes IA (74%) and IB (26%) and clustering of strains with strains from Germany and France, and those previously circulating in Puglia. Conclusion Vaccination and improved sanitation reduced the incidence of hepatitis A. Strict monitoring and improved vaccination coverage are needed to prevent disease resurgence. PMID:23098290

Spatial distribution estimation of malaria in northern China and its scenarios in 2020, 2030, 2040 and 2050.

PubMed

Song, Yongze; Ge, Yong; Wang, Jinfeng; Ren, Zhoupeng; Liao, Yilan; Peng, Junhuan

2016-07-07

Malaria is one of the most severe parasitic diseases in the world. Spatial distribution estimation of malaria and its future scenarios are important issues for malaria control and elimination. Furthermore, sophisticated nonlinear relationships for prediction between malaria incidence and potential variables have not been well constructed in previous research. This study aims to estimate these nonlinear relationships and predict future malaria scenarios in northern China. Nonlinear relationships between malaria incidence and predictor variables were constructed using a genetic programming (GP) method, to predict the spatial distributions of malaria under climate change scenarios. For this, the examples of monthly average malaria incidence were used in each county of northern China from 2004 to 2010. Among the five variables at county level, precipitation rate and temperature are used for projections, while elevation, water density index, and gross domestic product are held at their present-day values. Average malaria incidence was 0.107 ‰ per annum in northern China, with incidence characteristics in significant spatial clustering. A GP-based model fit the relationships with average relative error (ARE) = 8.127 % for training data (R(2) = 0.825) and 17.102 % for test data (R(2) = 0.532). The fitness of GP results are significantly improved compared with those by generalized additive models (GAM) and linear regressions. With the future precipitation rate and temperature conditions in Special Report on Emission Scenarios (SRES) family B1, A1B and A2 scenarios, spatial distributions and changes in malaria incidences in 2020, 2030, 2040 and 2050 were predicted and mapped. The GP method increases the precision of predicting the spatial distribution of malaria incidence. With the assumption of varied precipitation rate and temperature, and other variables controlled, the relationships between incidence and the varied variables appear sophisticated nonlinearity

Three-dimensional geometry and tectonostratigraphy of the Pennine zone, Central Alps, Switzerland and Northern Italy

NASA Astrophysics Data System (ADS)

Maxelon, Michael; Mancktelow, Neil S.

2005-08-01

Continental collision during Alpine orogenesis entailed a polyphase deformation history (D 1-D 5) in the Pennine zone of the Central Alps. The regional tectonostratigraphy was basically developed during D 1 and D 2, characterised by isoclinal, typically north-closing recumbent anticlines, separated by pinched-in synclines, on the scale of tens of kilometres. Later deformation phases (D 3 and D 4) warped the stack into wavy to open folds. Exhumation of this zone resulted locally in later vertical shortening and folding of already steep fabrics (D 5). Three-dimensional models of the nappe pile were constructed, based on geostatistical assessment of the regional foliation field and considering the abundant structural field data. These models indicate the existence of five principal tectonostratigraphic levels developed during D 1 and thus equivalent to nappe units s. str.: the Gotthard, the Leventina-Antigorio, the Maggia-Simano (and probably the Monte Leone as well as the Composite Lepontine Series), Lebendun-Soja and Adula-Cima Lunga levels. All these tectonic units formed part of the passive continental margin of Europe prior to the onset of the Alpine orogenesis. Individual isoclinal post-nappe folds reflect relative displacements on the order of 40 km or more. The most prominent D 2 post-nappe structure is the Wandfluhhorn Fold, structurally equivalent to the northern closure of the Leventina-Lucomagno Antiform. The Lebendun and Monte Leone folds are of similar magnitudes and also affect the whole nappe pile, whereas the smaller Mogno and Molare synforms only refold the Maggia-Simano nappe internally. Principal D 3 and D 4 structures are the tight Mergoscia Synform directly north of the Insubric Fault between Bellinzona and Locarno (Southern Steep Belt), the Maggia Steep Zone, forming the steep western limb of the Campo Tencia Synform and subdividing the Lepontine dome into the Simplon and Ticino subdomes, the Chiéra Synform steepening the dominant foliation in

Epidemiology of haemolytic uremic syndrome in children. Data from the North Italian HUS network.

PubMed

Ardissino, Gianluigi; Salardi, Stefania; Colombo, Elisa; Testa, Sara; Borsa-Ghiringhelli, Nicolò; Paglialonga, Fabio; Paracchini, Valentina; Tel, Francesca; Possenti, Ilaria; Belingheri, Mirco; Civitillo, Cristina Felice; Sardini, Stefano; Ceruti, Rossella; Baldioli, Carlo; Tommasi, Paola; Parola, Luciana; Russo, Fiorella; Tedeschi, Silvana

2016-04-01

Despite the severity of HUS and the fact that it represents a leading cause of acute kidney injury in children, the general epidemiology of HUS is all but well documented. The present study provides updated, population-based, purely epidemiological information on HUS in childhood from a large and densely populated area of northern Italy (9.6 million inhabitants, 1.6 million children). We systematically reviewed the files concerning patients with STEC-HUS and atypical HUS (aHUS) over a 10-year observation period (January 2003-December 2012). We included all incident cases with a documented first episode of HUS before the age of 18 years. We identified 101 cases of HUS during the 10 years. The overall mean annual incidence was 6.3 cases/million children aged <18 years (range 1.9-11.9), and 15.7/million of age-related population (MARP) among subjects aged <5 years; aHUS accounted for 11.9 % of the cases (mean incidence 0.75/MARP). The overall case fatality rate was 4.0 % (3.4 % STEC-HUS, 8.3 % aHUS). Given the public health impact of HUS, this study provides recent, population-based epidemiological data useful for healthcare planning and particularly for estimating the financial burden that healthcare providers might have to face in treating HUS, whose incidence rate seems to increase in Northern Italy. • HUS is a rare disease, but it represents the leading cause of acute kidney injury in children worldwide. • STEC-HUS (also called typical, D + HUS) is more common compared to atypical HUS, but recent, population-based epidemiological data (incidence) are scanty. What is New: • Comprehensive, population-based epidemiological data concerning both typical and atypical HUS based on a long observational period.

Detecting human presence at the border of the Northeastern Italian Pre-Alps. 14C dating at Rio Secco cave as expression of the first Gravettian and the late mousterian in the Northern Adriatic Region.

PubMed

Talamo, Sahra; Peresani, Marco; Romandini, Matteo; Duches, Rossella; Jéquier, Camille; Nannini, Nicola; Pastoors, Andreas; Picin, Andrea; Vaquero, Manuel; Weniger, Gerd-Christian; Hublin, Jean-Jacques

2014-01-01

In the northern Adriatic regions, which include the Venetian region and the Dalmatian coast, late Neanderthal settlements are recorded in few sites and even more ephemeral are remains of the Mid-Upper Palaeolithic occupations. A contribution to reconstruct the human presence during this time range has been produced from a recently investigated cave, Rio Secco, located in the northern Adriatic region at the foot of the Carnic Pre-Alps. Chronometric data make Rio Secco a key site in the context of recording occupation by late Neanderthals and regarding the diffusion of the Mid-Upper Palaeolithic culture in a particular district at the border of the alpine region. As for the Gravettian, its diffusion in Italy is a subject of on-going research and the aim of this paper is to provide new information on the timing of this process in Italy. In the southern end of the Peninsula the first occupation dates to around 28,000 14C BP, whereas our results on Gravettian layer range from 29,390 to 28,995 14C years BP. At the present state of knowledge, the emergence of the Gravettian in eastern Italy is contemporaneous with several sites in Central Europe and the chronological dates support the hypothesis that the Swabian Gravettian probably dispersed from eastern Austria.

Comparison of the results of different scale hydrogeological models on a terraced slope of Valtellina (Northern Italy)

NASA Astrophysics Data System (ADS)

Camera, C.; Apuani, T.; Masetti, M.; Mele, M.

2012-04-01

The aim of this work was to understand and reproduce the hydrological dynamics of a slope that is terraced by dry-stone retaining walls. At first, the processes of interest were analyzed with a classical 2D unsaturated-saturated finite elements analysis, reproducing the geometry of a single terrace. In a second moment, a raster analysis at the slope scale was performed. The studied slope is located in Valtellina (Northern Italy), near the village of Tresenda, and in the last 30 years it experienced several soil slip/debris flow events that in 1983 caused 18 victims. Direct observation of the events of 1983 permitted to recognize the principal triggering cause of these events in the formation of an overpressure at the base of a dry-stone wall, that caused its failure. Using field tests and monitoring activity as input and calibration data respectively, the 2D model is able to explain the mechanisms of rainfall infiltration that can lead to the formation and evolution of a perched groundwater table at the contact between the bedrock and the walls backfill soil. Once calibrated and validated the model has been used to investigate the influence of different parameters on the studied processes, such as walls height, bedrock slope angle, and changes of both isotropic and anisotropic saturated hydraulic conductivity of soil and wall. From this sensitivity analysis, one of the most interesting results is the ability of the model to well differentiate the behaviour of a well maintained wall with an higher hydraulic conductivity than soil, from a poorly maintained wall that has lost part of its drainage capacity. In fact, only in this latter circumstance significant pore-water pressures can form at the base of the retaining structure. Moving the problem to the slope scale, although the used raster-model takes into account both the unsaturated and saturated components of flux as the 2D model, it is less precise in the description of the processes involved in the formation of

Documenting Mica Microstructures in Mylonites of the Cossato-Mergozzo-Brissago Line, Northern Italy

NASA Astrophysics Data System (ADS)

Aslin, Joe; Mariani, Elisabetta; Wheeler, John

2016-04-01

The rheology of the Earth's crust is ultimately a function of the properties of its constituent minerals. Nowhere are the results of applied tectonic stresses within the Earth's crust more evident than along large scale fault zones and shear zones where strains become focussed producing localised deformation and displacement. These dynamic tectonic discontinuities are often dominated by fault rocks and mylonites that contain an abundance of phyllosilicates (such as micas) whose inherent weakness, relative to other silicate phases (Mariani et al. 2006), acts to concentrate deformation along these narrow regions. Experimental studies show that even in rocks where the concentration of weak phases, such as micas, is low, their effect on the strength and fabric of the rock is significant due to processes such as strain-induced interconnectivity (Holyoke & Tullis 2006). Once this interconnectivity has been established, very high strains can be accommodated within very narrow regions, termed shear bands or micro-shear zones. In this study, a combination of optical and scanning electron microscope (SEM) based techniques including electron backscatter diffraction (EBSD) have been used to observe and document features that are indicative of such processes within samples collected from the Cossato-Mergozzo-Brissago (CMB) shear zone in North Western Italy. This tectonic discontinuity is interpreted to be of Permian age and separates the metapelitic schists of the Kinzigite formation of the lower crustal Ivrea-Verbano zone from the mid-crustal schists and amphibolites of the Serie dei Laghi. Despite its present vertical attitude, the CMB line is believed to have formed as a gently inclined, mid-crustal shear zone during the early stages of post-Hercynian crustal stretching (Rutter et al. 2007). This has produced mylonites composed predominantly of quartz, feldspar and abundant phyllosilicates which serve as perfect natural examples on which to study the distribution of micas

High resolution estimates of the corrosion risk for cultural heritage in Italy.

PubMed

De Marco, Alessandra; Screpanti, Augusto; Mircea, Mihaela; Piersanti, Antonio; Proietti, Chiara; Fornasier, M Francesca

2017-07-01

Air pollution plays a pivotal role in the deterioration of many materials used in buildings and cultural monuments causing an inestimable damage. This study aims to estimate the impacts of air pollution (SO 2 , HNO 3 , O 3 , PM 10 ) and meteorological conditions (temperature, precipitation, relative humidity) on limestone, copper and bronze based on high resolution air quality data-base produced with AMS-MINNI modelling system over the Italian territory over the time period 2003-2010. A comparison between high resolution data (AMS-MINNI grid, 4 × 4 km) and low resolution data (EMEP grid, 50 × 50 km) has been performed. Our results pointed out that the corrosion levels for limestone, copper and bronze are decreased in Italy from 2003 to 2010 in relation to decrease of pollutant concentrations. However, some problem related to air pollution persists especially in Northern and Southern Italy. In particular, PM 10 and HNO 3 are considered the main responsible for limestone corrosion. Moreover, the high resolution data (AMS-MINNI) allowed the identification of risk areas that are not visible with the low resolution data (EMEP modelling system) in all considered years and, especially, in the limestone case. Consequently, high resolution air quality simulations are suitable to provide concrete benefits in providing information for national effective policy against corrosion risk for cultural heritage, also in the context of climate changes that are affecting strongly Mediterranean basin. Copyright © 2017 Elsevier Ltd. All rights reserved.

Epidemiological Study of Huntington's Disease in the Province of Ferrara, Italy.

PubMed

Carrassi, Erika; Pugliatti, Maura; Govoni, Vittorio; Sensi, Mariachiara; Casetta, Ilaria; Granieri, Enrico

2017-01-01

Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder caused by the abnormal expansion of CAG triplet repeat. We aimed to reappraise HD epidemiology in a northern Italian population, in relation to introduction of genetic testing. Through ICD-9M code 333.4 and medical fare exemption code RF0080, HD cases were identified from administrative health data and medical records from the Units of Neurology and Genetics, Ferrara University Hospital, and from other provincial neurological structures. HD mean annual incidence rate in 1990-2009 was 0.3 per 100,000 (95% CI 0.2-0.5). All incident cases were found to have symptoms of the disease's classic form, and neither juvenile nor the rigid Westphal variant was detected. The mean (SD) age at onset was 50.2 (12.7 years; range 32-82 years), 54.9 (14.6) for men and 45.8 (9.4) for women. On prevalence day, December 31, 2014, HD prevalence was 4.2 per 100,000 (95% CI 2.4-7.0), with a male:female ratio of 1:2. The prevalence and incidence of HD in our population were lower than the prevalence and incidence reported for other European and Italian populations, but higher compared to those of Asia, Africa, and Eastern Europe. Compared to previous studies, HD incidence and prevalence did not change significantly. © 2017 S. Karger AG, Basel.

Association between meteorological factors and bacillary dysentery incidence in Chaoyang city, China: an ecological study

PubMed Central

Zhao, Yang; Zhu, Yaxin; Zhu, Zhiwei; Qu, Bo

2016-01-01

Objectives To quantify the relationship between meteorological factors and bacillary dysentery incidence. Design Ecological study. Setting We collected bacillary dysentery incidences and meteorological data of Chaoyang city from the year 1981 to 2010. The climate in this city was a typical northern temperate continental monsoon. All meteorological factors in this study were divided into 4 latent factors: temperature, humidity, sunshine and airflow. Structural equation modelling was used to analyse the relationship between meteorological factors and the incidence of bacillary dysentery. Material Incidences of bacillary dysentery were obtained from the Center for Disease Control and Prevention of Chaoyang city, and meteorological data were collected from the Bureau of Meteorology in Chaoyang city. Primary outcome measures The indexes including χ2, root mean square error of approximation (RMSEA), comparative fit index (CFI), standardised root mean square residual (SRMR) and goodness-of-fit index (GFI) were used to evaluate the goodness-of-fit of the theoretical model to the data. The factor loads were used to explore quantitative relationship between bacillary dysentery incidences and meteorological factors. Results The goodness-of-fit results of the model showing that RMSEA=0.08, GFI=0.84, CFI=0.88, SRMR=0.06 and the χ2 value is 231.95 (p=0.0) with 15 degrees of freedom. Temperature and humidity factors had positive correlations with incidence of bacillary dysentery, with the factor load of 0.59 and 0.78, respectively. Sunshine had a negative correlation with bacillary dysentery incidence, with a factor load of −0.15. Conclusions Humidity and temperature should be given greater consideration in bacillary dysentery prevention measures for northern temperate continental monsoon climates, such as that of Chaoyang. PMID:27940632

Family lifestyle and childhood obesity in an urban city of Northern Italy.

PubMed

Bracale, Renata; Milani Marin, Laura Emma; Russo, Vincenzo; Zavarrone, Emma; Ferrara, Emanuela; Balzaretti, Claudia; Valerio, Alessandra; Pasanisi, Fabrizio; Nisoli, Enzo; Carruba, Michele O

2015-09-01

Over the last decades, the prevalence of overweight and obesity in elementary school children has steadily increased worldwide. This phenomenon is also linked to food habits. The main purpose of our study was to understand the role that environmental factors may play in this context; in particular, we investigated how and to what extent family food habits and children lifestyle are associated with the spread of children obesity. One hundred and nine primary schools, with 6-11-year-old children (n = 14,500), were recruited for this cross-sectional study in Milan (Italy). Children anthropometric data were measured and reported by parents; citizenship, fruit and vegetable consumption data of both parents and children were collected. Time spent watching television and doing physical activity was also investigated in children. The study revealed that children's vegetable (not fruit) consumption was positively associated with physical activity, while negatively associated with time watching TV; in particular, fewer hours spent watching television were a stronger protective factor than more hours spent doing physical activity. Moreover, the parental feeding style was associated with children's attitudes toward consumption of fruit and vegetable. Family characteristics (family size and level of parents' education) and children gender were associated to the risk of being overweight/obese. Our findings support the relevance of environmental factors in childhood food consumption and BMI distribution among children in an urban city. This is the reason why we stress the need to design ad hoc interventions, which should be developed in accordance with the socio-economic peculiarities of a cosmopolitan city suburb.

Canopy-scale flux measurements and bottom-up emission estimates of volatile organic compounds from a mixed oak and hornbeam forest in northern Italy

NASA Astrophysics Data System (ADS)

Acton, W. Joe F.; Schallhart, Simon; Langford, Ben; Valach, Amy; Rantala, Pekka; Fares, Silvano; Carriero, Giulia; Tillmann, Ralf; Tomlinson, Sam J.; Dragosits, Ulrike; Gianelle, Damiano; Hewitt, C. Nicholas; Nemitz, Eiko

2016-06-01

This paper reports the fluxes and mixing ratios of biogenically emitted volatile organic compounds (BVOCs) 4 m above a mixed oak and hornbeam forest in northern Italy. Fluxes of methanol, acetaldehyde, isoprene, methyl vinyl ketone + methacrolein, methyl ethyl ketone and monoterpenes were obtained using both a proton-transfer-reaction mass spectrometer (PTR-MS) and a proton-transfer-reaction time-of-flight mass spectrometer (PTR-ToF-MS) together with the methods of virtual disjunct eddy covariance (using PTR-MS) and eddy covariance (using PTR-ToF-MS). Isoprene was the dominant emitted compound with a mean daytime flux of 1.9 mg m-2 h-1. Mixing ratios, recorded 4 m above the canopy, were dominated by methanol with a mean value of 6.2 ppbv over the 28-day measurement period. Comparison of isoprene fluxes calculated using the PTR-MS and PTR-ToF-MS showed very good agreement while comparison of the monoterpene fluxes suggested a slight over estimation of the flux by the PTR-MS. A basal isoprene emission rate for the forest of 1.7 mg m-2 h-1 was calculated using the Model of Emissions of Gases and Aerosols from Nature (MEGAN) isoprene emission algorithms (Guenther et al., 2006). A detailed tree-species distribution map for the site enabled the leaf-level emission of isoprene and monoterpenes recorded using gas-chromatography mass spectrometry (GC-MS) to be scaled up to produce a bottom-up canopy-scale flux. This was compared with the top-down canopy-scale flux obtained by measurements. For monoterpenes, the two estimates were closely correlated and this correlation improved when the plant-species composition in the individual flux footprint was taken into account. However, the bottom-up approach significantly underestimated the isoprene flux, compared with the top-down measurements, suggesting that the leaf-level measurements were not representative of actual emission rates.

Canopy-scale flux measurements and bottom-up emission estimates of volatile organic compounds from a mixed oak and hornbeam forest in northern Italy

NASA Astrophysics Data System (ADS)

Acton, W. J. F.; Schallhart, S.; Langford, B.; Valach, A.; Rantala, P.; Fares, S.; Carriero, G.; Tillmann, R.; Tomlinson, S. J.; Dragosits, U.; Gianelle, D.; Hewitt, C. N.; Nemitz, E.

2015-10-01

This paper reports the fluxes and mixing ratios of biogenically emitted volatile organic compounds (BVOCs) 4 m above a mixed oak and hornbeam forest in northern Italy. Fluxes of methanol, acetaldehyde, isoprene, methyl vinyl ketone + methacrolein, methyl ethyl ketone and monoterpenes were obtained using both a proton transfer reaction-mass spectrometer (PTR-MS) and a proton transfer reaction-time of flight-mass spectrometer (PTR-ToF-MS) together with the methods of virtual disjunct eddy covariance (PTR-MS) and eddy covariance (PTR-ToF-MS). Isoprene was the dominant emitted compound with a mean day-time flux of 1.9 mg m-2 h-1. Mixing ratios, recorded 4 m above the canopy, were dominated by methanol with a mean value of 6.2 ppbv over the 28 day measurement period. Comparison of isoprene fluxes calculated using the PTR-MS and PTR-ToF-MS showed very good agreement while comparison of the monoterpene fluxes suggested a slight over estimation of the flux by the PTR-MS. A basal isoprene emission rate for the forest of 1.7 mg m-2 h-1 was calculated using the MEGAN isoprene emissions algorithms (Guenther et al., 2006). A detailed tree species distribution map for the site enabled the leaf-level emissions of isoprene and monoterpenes recorded using GC-MS to be scaled up to produce a "bottom-up" canopy-scale flux. This was compared with the "top-down" canopy-scale flux obtained by measurements. For monoterpenes, the two estimates were closely correlated and this correlation improved when the plant species composition in the individual flux footprint was taken into account. However, the bottom-up approach significantly underestimated the isoprene flux, compared with the top-down measurements, suggesting that the leaf-level measurements were not representative of actual emission rates.

Wild food plants traditionally consumed in the area of Bologna (Emilia Romagna region, Italy).

PubMed

Sansanelli, Sabrina; Tassoni, Annalisa

2014-09-25

This research was performed in an area belonging to the province of the city of Bologna (Emilia-Romagna region, Northern Italy). The purpose of the present survey was to record the local knowledge concerning traditional uses of wild food plants and related practices, such as gathering, processing, cooking, therapeutic uses, with the aim of preserving an important part of the local cultural heritage. Thirty-nine people still retaining Traditional Local Knowledge (TLK) were interviewed between March-April 2012 and September-October 2013 by means of open and semi-structured ethnobotanical interviews. For each plant species mentioned, we recorded the botanical family, the English common name, the Italian common and/or folk names, the parts of the plant used, the culinary preparation, and the medicinal usage. The relative frequency of citation index (RFC), a tool that measures the local cultural importance of a plant species, was also included. The folk plants mentioned by the respondents belonged to 33 botanical families, of which the Rosaceae (14 plants) and the Asteraceae (9 plants) were the most representative. The species with the highest RFC index (0.77) were Crepis vesicaria subsp. taraxacifolia (Thuill) Thell and Taraxacum officinale Weber. Eleven folk plants were indicated as having therapeutic effects. T. officinale Weber, C. vesicaria subsp. taraxacifolia (Thuill) Thell and Sonchus spp., which are used as food, were reported to be depurative, blood cleaning, refreshing, diuretic and laxative. The most commonly used species was Urtica spp, which was also the most frequently cited for medicinal uses. The present survey documented the wild food plant traditional knowledge of an area belonging to the province of the city of Bologna (Emilia-Romagna region, Northern Italy). The general perception obtained is that on one side the TLK related to wild food plants has strongly been eroded, mainly due to immigration and urbanization phenomena, whereas on the other side

[Epidemiology of cancer in Italy: from real data to the need for cancer networks.

PubMed

Pinto, Carmine; Mangone, Lucia

2016-10-01

The Italian Association of Medical Oncology (AIOM) and the Italian Association of Cancer Registries (AIRTUM) provide a reliable estimation of the incidence of cancer in Italy. The most outstanding data point to the steadily increasing efficacy of novel therapies, allowing patients to live longer and have a better quality of life, and the number of citizens being diagnosed with cancer - more than three million people, 4.9% of the population. Over the last years, a significant reduction in cancer incidence has been recorded among men with an opposite tendency among women. However, decreased mortality rates are observed in both sexes as a result of primary prevention measures and the promotion of large-scale national screening programs. In this scenario, cancer networks may play a key role. Quality of care could be substantially improved only if regional cancer networks are implemented on the basis of shared pathways, so as to guarantee equity of access in every phase of the disease.

Exploring reasons for non-vaccination against human papillomavirus in Italy.

PubMed

Giambi, Cristina; D'Ancona, Fortunato; Del Manso, Martina; De Mei, Barbara; Giovannelli, Ilaria; Cattaneo, Chiara; Possenti, Valentina; Declich, Silvia

2014-11-11

In Italy, free-of-charge HPV vaccination is offered to 11-year-old girls since 2007. The National Immunization Plan established the target coverage at a minimum of 70%; it should increase to 95% within 3-year time frame. In 2012, four year after the introduction of HPV vaccination, coverage was stable at 69%. We conducted a national cross-sectional study to explore barriers to vaccination in Italy. Vaccination services selected, through the immunization registries, a sample of unvaccinated girls born in 1997 or 1998 and posted to their families a 23-items questionnaire inquiring barriers to vaccination, HPV knowledge, source of information on HPV, perception of risk of contracting HPV, advice from consulted health professionals on HPV vaccination. We analysed 1,738 questionnaires. Main barriers were fear of adverse events (reported by 80% of families), lack of trust in a new vaccine (76%), discordant information received by health professionals (65%) and scarce information on HPV vaccination (54%). Overall, 54% of families replied correctly to more than half of 10 questions exploring knowledge on HPV vaccination. Families with a high knowledge score were more likely to live in Northern and Central Italy, be Italian, have a high educational level, include a mother who attended cervical screening regularly and consult more information sources. Although paediatricians/general practitioners and gynaecologists were considered the most trusted source of information by 79% and 61% of respondents, they were consulted only by 49% and 31%. Among parents who discussed vaccination with a physician, 28% received discordant advices and 31% received the recommendation of accepting vaccination. Fear of adverse events, discordance of information and advices from physicians, and scarce information were the more commonly reported barriers to HPV vaccination. Health professionals played a key role as information providers, thus they must be better trained to provide clear notions

The atmospheric degradation of a durable lithotype used in Northern Italy: the Oira stone

NASA Astrophysics Data System (ADS)

Toniolo, Lucia; Bugini, Roberto; Gulotta, Davide

2016-04-01

The cathedral of Monza is a masterpiece of the northern Italian architectural heritage dated at the beginning of the XIV century. Its façade was modified over time as a result of the variation of the general plan and its current appearance is defined by six main pillars which identify five sectors, the central one hosting the main portal and a huge rose window. All the architectural elements and sculptures were realized in stone using several and different local lithotypes, including marbles, limestones, sandstones and volcanic stones. One of the most distinctive hallmarks of the façade is the alternated presence of rows of white and dark stones for the flat blocks which cover the masonry. Originally, the white rows were realized with different types of whitish marbles, whereas the dark ones were made by Varenna stone, a local black sedimentary rock. Unfortunately, this stone type extensively deteriorated as a result of the outdoor exposition and it was therefore completely substituted with blocks of dark green-coloured Oira stone during the restoration of the façade carried out at the end of XIX century by the famous architect Luca Beltrami [1]. Pietra d'Oira is a dark green peridotite, with olivine crystals partly altered to serpentine and pertains to Metabasites embedded in gneiss and micaschist of Strona - Ceneri zone (late Palaeozoic) and outcrops on the western shore of lake Orta (North-western Piedmont) near the Oira village. In the early XX century, Pietra d'Oira replaced some stone by then badly decayed as Triassic black limestone from several quarry sites of Prealps or dark grey limestone from Saltrio quarries. Several buildings were involved in these restoration works: the façade of the Church of Certosa (Pavia, XV century), Cappella Colleoni (Bergamo, last quarter of XV century) and, as reported, the façade of the Monza cathedral. The present paper reports the study of the degradation of the Oira stone exposed to outdoor atmospheric conditions

Increase in the incidence of type 1 diabetes in Israeli children following the Second Lebanon War.

PubMed

Zung, Amnon; Blumenfeld, Orit; Shehadeh, Naim; Dally Gottfried, Orna; Tenenbaum Rakover, Yardena; Hershkovitz, Eli; Gillis, David; Zangen, David; Pinhas-Hamiel, Orit; Hanukoglu, Aaron; Rachmiel, Marianna; Shalitin, Shlomit

2012-06-01

Type 1 diabetes is an autoimmune disease occurring in genetically susceptible individuals. The precipitating cause is unclear. Recently, the Second Lebanon War exposed a large civilian population in northern Israel to significant psychological stress in the form of repeated barrages of missile attacks. We hypothesized that trends in regional incidence of type 1 diabetes before and after the war would reflect an association with stress. All type 1 diabetes patients aged 0-17 yr who were reported to the Israel Juvenile Diabetes Register (n = 1822) in the four pre-war (2002-2005) and two post-war years (2006-2007) were included in the study. The patients were stratified by gender, age, ethnicity, family history of type 1 diabetes, season at diagnosis, and region of residency, namely, those who lived in the northern regions that were attacked and those in other regions. The post-war incidence of type 1 diabetes was increased in the northern regions (rate ratio, RR = 1.27; p = 0.037), with no change in the other regions. This change was more prominent in males (RR = 1.55; p = 0.005) but similar in summer and winter, in different ages, and in different ethnic groups. There was no change in the proportion of new patients with a family history of the disease. For the first time in a large population, we found a positive association between the trauma of war and an increase in the incidence of type 1 diabetes in children and adolescents. The increase in incidence was not associated with genetic susceptibility to the disease. © 2011 John Wiley & Sons A/S.

Invasive bacterial diseases: national surveillance in Italy and vaccination coverage in the Local Health Agency 4 "Chiavarese", Liguria region (Italy).

PubMed

Trucchi, C; Zoppi, G

2012-06-01

this disease, too. We evaluated vaccination coverage in LHA 4 from 2003 to 2008. VC levels against Haemophilus influenzae are excellent; the objective indicated in the 2005-2007 NIP (> or = 95%) has therefore been reached. Vaccination coverage levels against Streptococcus pneumoniae and Neisseria meningitidis serogroup C at the 24th month of age are also good. However, we need to implement specific immunization strategies for adolescents, since the vaccination coverage levels are not completely satisfactory. The improvement of the national invasive disease surveillance system has provided better knowledge of the size of the problem and the impact of immunization strategies on the incidence of invasive bacterial diseases. Furthermore, immunization policies in Italy display territorial heterogeneity. Vaccination coverage levels against Haemophilus influenzae, Streptococcus pneumoniae and Neisseria meningitidis at the 24th month in LHA 4 are very high. In adolescents (15 year-olds) the immunization coverage are good but needs to be improved through specific strategies, such as raising the awareness of healthcare workers, involving general practitioners and educating the target population.

First-episode psychosis and migration in Italy (PEP-Ita migration): a study in the Italian mental health services

PubMed Central

2014-01-01

Background It has been frequently reported a higher incidence of psychotic disorders in immigrants than in native populations. There is, however, a lack of knowledge about risk factors which may explain this phenomenon. A better understanding of the causes of psychosis among first-generation migrants is highly needed, particularly in Italy, a country with a recent massive migration. Methods/Design The “Italian study on first-episode psychosis and migration (PEP-Ita)” is a prospective observational study over a two-year period (1 January 2012–31 December 2013) which will be carried out in 11 Italian mental health centres. All participating centres will collect data about all new cases of migrants with first-episode psychosis. The general purpose (“core”) of the PEP-Ita study is to explore the socio-demographic and clinical characteristics, and the pathways to care of a population of first-episode psychosis migrants in Italy. Secondary aims of the study will be: 1) to understand risk and protective factors for the development of psychotic disorders in migrants; 2) to evaluate the correlations between psychopathology of psychotic disorders in migrants and socio-demographic characteristics, migration history, life experiences; 3) to evaluate the clinical and social outcomes of first-episode psychoses in migrants. Discussion The results of the PEP-Ita study will allow a better understanding of risk factors for psychosis in first-generation migrants in Italy. Moreover, our results will contribute to the development of prevention programmes for psychosis and to the improvement of early intervention treatments for the migrant population in Italy. PMID:24957972

Emerging organic contaminants in surface water and groundwater: a first overview of the situation in Italy.

PubMed

Meffe, Raffaella; de Bustamante, Irene

2014-05-15

This paper provides the first review of the occurrence of 161 emerging organic compounds (EOCs) in Italian surface water and groundwater. The reported EOCs belong to the groups of industrials, pharmaceuticals, estrogens and illicit drugs. Occurrence of 137 pesticides was also reported. The reviewed research works have been published between 1997 and 2013. The majority of the studies have been carried out in Northern Italy (n. 30) and to a lower extent in Central Italy (n. 13). Only a limited number of research studies report EOC concentrations in water resources of Southern Italy. The EOCs that have been more frequently studied are in the following descending order, pesticides (16), pharmaceuticals (15), industrials (13), estrogens (7) and illicit drugs (2). Research activities investigating the EOC occurrence in surface water are more numerous than those in groundwater. This is consistent with the higher complexity involved in groundwater sampling and EOC detection. Among the reported EOCs, industrials and pesticides are those occurring in both surface water and groundwater with the highest concentrations (up to 15 × 10(6) and 4.78 × 0(5)ng L(-1), respectively). Concentrations of pharmaceuticals in surface water reach a maximum of 3.59 × 10(3)ng L(-1), whereas only the antimicrobial agent josamycin has been encountered in groundwater with a concentration higher than 100 ng L(-1). Both estrogens and illicit drugs appeared in surface water with concentrations lower than 50 ng L(-1). Groundwater concentrations for estrogens were measured to be below the detection limits, whereas illicit drugs have so far not been studied in groundwater. The present review reveals the serious contamination status of Italian surface water and groundwater especially by pesticides, industrials and to a lower extent by pharmaceuticals and the necessity to foster the research on EOC occurrence in Italian water resources, in particular in Southern Italy where a limited number of

Temporal trends in adolescent pregnancies in Lombardy, Italy: 1996-2010.

PubMed

Parazzini, Fabio; Ricci, Elena; Cipriani, Sonia; Motta, Tiziano; Chiaffarino, Francesca; Malvezzi, Matteo; Bulfoni, Giuseppe

2013-04-01

Data from southern European countries concerning teenage pregnancy have not been properly analysed so far. We provide the temporal trend of adolescent pregnancy rates in Lombardy, Northern Italy. Using the hospital discharge register (1996-2010), teenage pregnancy-related admission rates per 1000 girls aged 13 to 19 years, residing in Lombardy, were computed. Miscarriage-, induced abortion-, and delivery ratios/100 pregnancies, and caesarean section ratio/100 deliveries, were calculated. The pregnancy rate increased from 9.07 in 1996-2000 to 10.20 in 2001-2005, and remained at that level (10.27) in 2006-2010. However, the rates by country of birth (native Italian and non-native Italian) showed a steady decline in 2003-2010, when data about residents in Lombardy, categorised by sex, age and country of birth, were available. The induced abortion rate rose from 5.38/1000 to 5.55/1000, then decreased slightly in 2006-2010. The abortion ratio/100 pregnancies diminished from 59.3 in 1996-2000 to 50.3 in 2006-2010. Between 1996 and 2010, the overall teenage pregnancy rate has risen in Lombardy. When the rates were calculated separately for adolescents born in Italy and immigrants, the trends reverted in the period 2003-2010: in both groups pregnancy- and birth rates steadily declined. Pregnancy-, abortion-, and birth rates in non-native Italians, after having dropped, are all still much higher than those among native Italians. Because the number of non-native Italian adolescent girls markedly increased over the last two decades, their group--with decreasing, but still higher, birth- and abortion rates--has caused the observed rise in those rates when all adolescents residing in Lombardy are considered indistinctly.

Seismic risk perception in Italy

NASA Astrophysics Data System (ADS)

Crescimbene, Massimo; La Longa, Federica; Camassi, Romano; Pino, Nicola Alessandro; Peruzza, Laura

2014-05-01

Risk perception is a fundamental element in the definition and the adoption of preventive counter-measures. In order to develop effective information and risk communication strategies, the perception of risks and the influencing factors should be known. This paper presents results of a survey on seismic risk perception in Italy conducted from January 2013 to present . The research design combines a psychometric and a cultural theoretic approach. More than 7,000 on-line tests have been compiled. The data collected show that in Italy seismic risk perception is strongly underestimated; 86 on 100 Italian citizens, living in the most dangerous zone (namely Zone 1), do not have a correct perception of seismic hazard. From these observations we deem that extremely urgent measures are required in Italy to reach an effective way to communicate seismic risk. Finally, the research presents a comparison between groups on seismic risk perception: a group involved in campaigns of information and education on seismic risk and a control group.

Origin of arsenic in groundwater from the multilayer aquifer in Cremona (northern Italy).

PubMed

Rotiroti, Marco; Sacchi, Elisa; Fumagalli, Letizia; Bonomi, Tullia

2014-05-20

An analysis of 70 wells that tap groundwater from depths of up to 260 m in and around the town of Cremona, N. Italy, shows that 50 of them contain more than 10 μg/L of arsenic. Concentrations of As >10 ppb are accompanied by concentrations of Fe ranging from <0.1 to 6 mg/L and high concentrations of NH4 and Mn (<19 and <1.3 mg/L, respectively). The associations suggest that the mechanism of mobilization of As is the reductive dissolution of Fe oxides driven by the degradation of peat, which is commonly found in the aquifer system. Groundwater in the aquifer has a component of downward flow via leakage through aquitards and flow through lateral discontinuities in them. Along these flow paths, As is released by reductive dissolution of Fe oxides in shallow and intermediate aquifers (0-85 m below surface), reaching up to 183 μg/L, and is attenuated (<95 μg/L) at greater depths (100-150 m). Coprecipitation in iron sulfides could play an important role in As attenuation at these depths. The lower As concentration (<37 μg/L) in the deepest aquifer (160-260 m) is less related to the As concentration of the overlying aquifers because the groundwater here has a component of upward flow.

Optimal placement of point detectors on Virginia's freeways : case studies of Northern Virginia and Richmond.

DOT National Transportation Integrated Search

2008-01-01

In Virginia, point detectors in the Northern Virginia and Hampton Roads regions are placed at approximately 1/2 mile spacing. This density is a product of early requirements for incident detection that have proven ineffective and perhaps unnecessary....

The epidemiology of homicide-suicide in Italy: a newspaper study from 1985 to 2008.

PubMed

Roma, Paolo; Spacca, Antonella; Pompili, Maurizio; Lester, David; Tatarelli, Roberto; Girardi, Paolo; Ferracuti, Stefano

2012-01-10

Homicide-suicide is an event in which the murderer commits suicide after the homicide. There are at least 14 epidemiological studies on the topic, and all have found that homicide-suicide is more common among family members. The murderers are most often males and the victims females. There is no recent research on this phenomenon in Italy. The purpose of the study was to evaluate the incidence of homicide-suicide in Italy over a period of 24 yrs and to compare Italian data with published international data. We used information gathered by press agencies and from the four major Italian newspapers. Between 1985 and 2008, 662 cases of homicide-suicide were identified, with 1776 deaths. The murderer was male in 84.6% of the cases, typically using a firearm. The most common motivation was romantic jealousy, followed by socio-economic stress. The rate of homicide-suicide was 0.04%. Comparison with international studies is not always possible due to the lack of information for certain categories. The common factors identified may be helpful for prevention. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

Terra and Aqua satellites track tiger mosquito invasion: modelling the potential distribution of Aedes albopictus in north-eastern Italy

PubMed Central

2011-01-01

Background The continuing spread of the Asian tiger mosquito Aedes albopictus in Europe is of increasing public health concern due to the potential risk of new outbreaks of exotic vector-borne diseases that this species can transmit as competent vector. We predicted the most favorable areas for a short term invasion of Ae. albopictus in north-eastern Italy using reconstructed daily satellite data time series (MODIS Land Surface Temperature maps, LST). We reconstructed more than 11,000 daily MODIS LST maps for the period 2001-09 (i.e. performed spatial and temporal gap-filling) in an Open Source GIS framework. We aggregated these LST maps over time and identified the potential distribution areas of Ae. albopictus by adapting published temperature threshold values using three variables as predictors (0°C for mean January temperatures, 11°C for annual mean temperatures and 1350 growing degree days filtered for areas with autumnal mean temperatures > 11°C). The resulting maps were integrated into the final potential distribution map and this was compared with the known current distribution of Ae. albopictus in north-eastern Italy. Results LST maps show the microclimatic characteristics peculiar to complex terrains, which would not be visible in maps commonly derived from interpolated meteorological station data. The patterns of the three indicator variables partially differ from each other, while winter temperature is the determining limiting factor for the distribution of Ae. albopictus. All three variables show a similar spatial pattern with some local differences, in particular in the northern part of the study area (upper Adige valley). Conclusions Reconstructed daily land surface temperature data from satellites can be used to predict areas of short term invasion of the tiger mosquito with sufficient accuracy (200 m pixel resolution size). Furthermore, they may be applied to other species of arthropod of medical interest for which temperature is a relevant

Mt. Vesuvius, Italy

NASA Image and Video Library

2001-10-22

This ASTER image of Mt. Vesuvius Italy was acquired September 26, 2000, and covers an area of 36 by 45 km. Vesuvius overlooks the city of Naples and the Bay of Naples in central Italy. In 79 AD, Vesuvius erupted cataclysmically, burying all of the surrounding cites with up to 30 m of ash. The towns of Pompeii and Herculanaeum were rediscovered in the 18th century, and excavated in the 20th century. They provide a snapshot of Roman life from 2000 years ago: perfectly preserved are wooden objects, food items, and the casts of hundreds of victims. Vesuvius is intensively monitored for potential signs of unrest that could signal the beginning of another eruption. The image is centered at 40.8 degrees north latitude, 14.4 degrees east longitude. http://photojournal.jpl.nasa.gov/catalog/PIA11091

Historical analysis of rainfall-triggered rockfalls: the case study of the disaster of the ancient hydrothermal Sclafani Spa (Madonie Mts, northern-central Sicily, Italy) in 1851

NASA Astrophysics Data System (ADS)

Contino, Antonio; Bova, Patrizia; Esposito, Giuseppe; Giuffré, Ignazio; Monteleone, Salvatore

2017-12-01

In 1851, the region of Sicily experienced many rainstorm-induced landslides. On 13 March 1851, a rainstorm brought about a severe rockfall disaster near the small town of Sclafani (Madonie Mountains, northern-central Sicily, Italy). Rocks detached from the carbonate crest of Mt Sclafani (813 m above sea level) and fell downslope, causing the collapse of the ancient hydrothermal spa (about 430 m above sea level) and burying it. Fortunately, there were no injuries or victims. Given its geological, geomorphological and tectonic features, the calcareous-dolomitic and carbonate-siliciclastic relief of Mt Sclafani is extremely prone to landsliding. This study combines the findings of detailed geological and geomorphological field surveys and of a critical review of documentary data. A thorough analysis of documentary sources and historical maps made it possible to identify the location (previously unknown) of the ancient spa. The rockfall dynamics was reconstructed by comparing field reconnaissance data and documentary sources. The 1851 event reconstruction is an example of the application of an integrated methodological approach, which can yield a propaedeutic, yet meaningful picture of a natural disaster, paving the way for further research (e.g. slope failure susceptibility, future land-use planning, protection of thermal springs and mitigation of the impact of similar disasters in this area). Indeed, the intensification of extreme weather events, caused by global warming induced by climate change, has increased the risk of recurrence of a catastrophic event, like that of the ancient Sclafani spa, which is always a potential threat.

Work- and non-work-related eye injuries in a highly industrialized area in northern Italy: comparison between two three-year periods (1994-1996 and 2005-2007).

PubMed

Semeraro, F; Polcini, C; Forbice, Eliana; Monfardini, A; Costagliola, C; Apostoli, P

2013-01-01

Ocular trauma is a major cause of monocular blindness and visual impairment in industrialized countries. The aim of this paper was to study epidemiology, causes, and clinical features of work-related and non-work-related eye injuries in a highly industrialized area of northern Italy. All patients hospitalized for eye injuries were enrolled. Two 3-year periods were studied (1994-1996 and 2005-2007). The variables analyzed included sex, age, social class of the patients, nature of the injuring agent (e.g., metal, plastic, etc.), place where the accident occurred (e.g., home, work, etc.), and time of the year (e.g., summer, winter, etc.). We enrolled 1001 men and 129 women. There were no significant differences between the two 3-year periods as regards distribution of sex, age, and location. Road-related injuries significantly decreased (p < 0.004). Comparison of injuring agents showed a decrease in metallic agents (p < 0.001) and an increase in lime agents (p < 0.001). Analysis of the type of trauma showed a decrease in blunt traumas (p < 0.001) and an increase in chemical injuries (p < 0.001) and actinic keratitis (p = 0.002). In the second 3-year period, we found a significant increase in injuries in non-Italian subjects (p < 0.001). Work-related injuries were the major cause of eye trauma. Road accident-related eye injuries dropped significantly in the second 3-year period. The adoption of higher safety standards, as well as information and educational campaigns, can significantly reduce work-related and non-work-related eye injuries.

Environmental and climatic conditions at a potential Glacial refugial site of tree species near the Southern Alpine glaciers. New insights from multiproxy sedimentary studies at Lago della Costa (Euganean Hills, Northeastern Italy)

NASA Astrophysics Data System (ADS)

Kaltenrieder, Petra; Belis, Claudio A.; Hofstetter, Simone; Ammann, Brigitta; Ravazzi, Cesare; Tinner, Willy

2009-12-01

It has been hypothesized that refugia of thermophilous tree species were located in Northern Italy very close to the Alps, though, this hypothesis has yet to be tested thoroughly. In contrast to Central and Southern Italy with its relative wealth of data, only a few fragmentary records are currently available from Northern Italy for the last Glacial (Würm, Weichselian). Our new study site Lago della Costa lies adjacent to the catchment of the megafans of the Alpine forelands and the braided rivers of the Northeastern Po Plain that have so far inhibited the recovery of continuous Glacial and Late-Glacial records. We analyze pollen, plant macrofossils, charcoal and ostracods to reconstruct the vegetation, fire and lake history for the period 33,000-16,000 cal. BP. We compare our data with Glacial records from Southern Europe to discuss similarities and dissimilarities between these potential refugial areas. A comparison with independent paleoclimatic proxies allows to assess potential linkages between environmental and climatic variability. New macrofossil and pollen data at Lago della Costa unambiguously document the local persistence of boreal tree taxa such as Larix decidua and Betula tree species around the study site during the last Glacial. The regular occurrence of pollen of temperate trees in the organic lake sediments (fine-detritus calcareous gyttja) suggests that temperate taxa such as Corylus avellana, Quercus deciduous, Tilia, Ulmus, Fraxinus excelsior, Carpinus, Abies alba and Fagus sylvatica, most likely survived the Last Glacial Maximum (LGM) at favorable sites in the Euganean Hills. The percentage values of temperate trees are comparable with those from Southern Europe (e.g. Monticchio in Southern Italy). We conclude that the Euganean Hills were one of the northernmost refugial areas of temperate taxa in Europe. However, the relative and absolute abundances of pollen of temperate trees are highly variable. Pollen-inferred declines of temperate tree

How to model the stability of terraced slopes? The case study of Tresenda (northern Italy)

NASA Astrophysics Data System (ADS)

Camera, Corrado; Apuani, Tiziana; Masetti, Marco

2015-04-01

Terraces are very common morphological features all around the Mediterranean Basin. They have been built to adapt the natural morphology of the territory to the development of anthropogenic activities, particularly agriculture. However, the increasing land abandonment during the last century is leading to soil degradation and stability issues, mainly due to lack of maintenance of these peculiar environments. The objective of this study was to develop a coupled hydrologic-stability model to identify possible triggering areas of superficial landslides during intense rainfall events. The model was tested on a slope uphill of the village of Tresenda, in Northern Italy, which experienced several superficial landslides in the last 35 years. Distributed stability analyses are usually carried out using an infinite slope approach, but in the case of terraces some basic assumptions of this method fail: the parallelism between topographical surface and potential sliding surface and the high ratio between slope length and failure surface depth are the most important examples. In addition, the interest is more on the stability of the terrace system (dry stone retaining wall and backfill soil) and not on soil alone. For these reasons, a stability analysis based on the global method of equilibrium is applied and soft coupled to a well know hydrological model (STARWARS). Sections of terrace, one cell wide, are recognized from the base of a wall to the top of the closest downstream one, and each cell (1 x 1 m2) is considered as a slice. The method of Sarma for circular and non-circular failure is applied. The very fine horizontal resolution (1 m) is crucial to take into consideration the hydrogeological and mechanical properties of dry stone walls (0.6-1.0 m wide). A sensitivity analysis was conducted for saturated water content, initial volumetric water content, the cohesion and friction angle of soil and walls and soil depth. The results of the sensitivity analysis showed that

Association between meteorological factors and bacillary dysentery incidence in Chaoyang city, China: an ecological study.

PubMed

Zhao, Yang; Zhu, Yaxin; Zhu, Zhiwei; Qu, Bo

2016-12-09

To quantify the relationship between meteorological factors and bacillary dysentery incidence. Ecological study. We collected bacillary dysentery incidences and meteorological data of Chaoyang city from the year 1981 to 2010. The climate in this city was a typical northern temperate continental monsoon. All meteorological factors in this study were divided into 4 latent factors: temperature, humidity, sunshine and airflow. Structural equation modelling was used to analyse the relationship between meteorological factors and the incidence of bacillary dysentery. Incidences of bacillary dysentery were obtained from the Center for Disease Control and Prevention of Chaoyang city, and meteorological data were collected from the Bureau of Meteorology in Chaoyang city. The indexes including χ 2 , root mean square error of approximation (RMSEA), comparative fit index (CFI), standardised root mean square residual (SRMR) and goodness-of-fit index (GFI) were used to evaluate the goodness-of-fit of the theoretical model to the data. The factor loads were used to explore quantitative relationship between bacillary dysentery incidences and meteorological factors. The goodness-of-fit results of the model showing that RMSEA=0.08, GFI=0.84, CFI=0.88, SRMR=0.06 and the χ 2 value is 231.95 (p=0.0) with 15 degrees of freedom. Temperature and humidity factors had positive correlations with incidence of bacillary dysentery, with the factor load of 0.59 and 0.78, respectively. Sunshine had a negative correlation with bacillary dysentery incidence, with a factor load of -0.15. Humidity and temperature should be given greater consideration in bacillary dysentery prevention measures for northern temperate continental monsoon climates, such as that of Chaoyang. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/.

Tropical Pacific forcing on decadal-to-centennial NAO-dominated precipitation variability in northern Mediterranean over the past 6500 years

NASA Astrophysics Data System (ADS)

Hu, H. M.; Shen, C. C.; Michel, V.; Jiang, X.; Mii, H. S.; Wang, Y.; Valensi, P.

2017-12-01

We present a multi-annual-resolved absolute-dated stalagmite-inferred precipitation record, with age precision as good as ±2 years, from northern Italy, to reflect North Atlantic Oscillation (NAO) dynamics since 6.5 ka (thousand years ago, before 1950 C.E.). Our record features millennial precipitation fluctuations punctuated by several centennial-scale drought periods centered at 5.6, 6.2, 4.2, 3.0 and 2.3 ka. The phase relationship with previous NAO-sensitive records suggests a multi-millennial southward migration of the northern Westerlies and enhanced NAO variability from the middle- to late-Holocene. We also found the multi-decadal to centennial rainfall amount could dramatically vary within few decades, possibly affecting ancient Mediterranean civilizations. Concurrence between northern Mediterranean precipitation and western tropical Pacific sea surface temperature records suggests the remote forcing on this NAO-dominated rainfall. We argue that the irregular NAO change nowadays could be related to high frequency of El Niño-Southern Oscillation events and might cause an inevitable abrupt hydroclimate change and irreparable impacts on the regional human society in the near future.

Smoke-free legislation and the incidence of paediatric respiratory infections and wheezing/asthma: interrupted time series analyses in the four UK nations

PubMed Central

Been, Jasper V.; Szatkowski, Lisa; van Staa, Tjeerd-Pieter; Leufkens, Hubert G.; van Schayck, Onno C.; Sheikh, Aziz; de Vries, Frank; Souverein, Patrick

2015-01-01

We investigated the association between introduction of smoke-free legislation in the UK (March 2006 for Scotland, April 2007 for Wales and Northern Ireland, and July 2007 for England) and the incidence of respiratory diseases among children. We extracted monthly counts of new diagnoses of wheezing/asthma and RTIs among children aged 0–12 years from all general practices in the Clinical Practice Research Datalink during 1997–2012. Interrupted time series analyses were performed using generalised additive mixed models, adjusting for underlying incidence trends, population size changes, seasonal factors, and pandemic influenza, as appropriate. 366,642 new wheezing/asthma diagnoses and 4,324,789 RTIs were observed over 9,536,003 patient-years. There was no statistically significant change in the incidence of wheezing/asthma after introduction of smoke-free legislation in England (incidence rate ratio (IRR) 0.94, 95% CI 0.81–1.09) or any other UK country (Scotland: IRR 0.99, 95% CI 0.83–1.19; Wales: IRR 1.09, 95% CI 0.89–1.35; Northern Ireland: IRR 0.96, 95% CI 0.76–1.22). Similarly no statistically significant changes in RTI incidence were demonstrated (England: IRR 0.95, 95% CI 0.86–1.06; Scotland: IRR 0.96, 95% CI 0.83–1.11; Wales: IRR 0.97, 95% CI 0.86–1.09; Northern Ireland: IRR 0.90, 95% CI 0.79–1.03). There were no demonstrable reductions in the incidence of paediatric wheezing/asthma or RTIs following introduction of smoke-free legislation in the UK. PMID:26463498

Incidence and outcome of subtypes of ischaemic stroke: initial results from the north East melbourne stroke incidence study (NEMESIS).

PubMed

Dewey, Helen M; Sturm, Jonathan; Donnan, Geoffrey A; Macdonell, Richard A L; McNeil, John J; Thrift, Amanda G

2003-01-01

Information about the incidence and outcome of stroke subtypes is necessary to understand the likely impact of stroke prevention and treatment strategies. The purpose of this study was to determine the incidence and outcome of subtypes of cerebral infarction (CI). All strokes occurring in a population of 133816 in Melbourne, Australia, during a 12-month period of 1996 and 1997 were identified and cases of CI subtyped according to the Oxfordshire Community Stroke Project classification. 276 'first-ever-in-a-lifetime' stroke cases were registered. CI accounted for 72% of cases. Annual incidence rates per 100000 persons adjusted to the 'world' population were 11 (95% CI, 4-18) for TACI, 25 (95% CI, 15-35) for PACI, 17 (95% CI, 9-25) for POCI and 18 (95% CI, 10-26) for LACI. 28-day case fatality was highest for TACI (35%; 95% CI, 19-51%) and first year recurrence rate highest for PACI (17%; 95% CI, 8-26%). TACI had the poorest functional outcome at 3 and 12 months. These findings are similar to those of two previous studies conducted in the northern hemisphere. Copyright 2003 S. Karger AG, Basel

Knowledge of human papillomavirus infection and its prevention among adolescents and parents in the greater Milan area, Northern Italy.

PubMed

Pelucchi, Claudio; Esposito, Susanna; Galeone, Carlotta; Semino, Margherita; Sabatini, Caterina; Picciolli, Irene; Consolo, Silvia; Milani, Gregorio; Principi, Nicola

2010-06-28

In order to be widely accepted by users, the implementation of a new health intervention requires them to be adequately informed about its clinical importance, benefits and risks. The aim of this study was to provide data on the knowledge of Italian adolescents and parents concerning human papillomavirus (HPV) infection and its prevention in order to allow the development of adequate training programmes. Between 2 May and 15 June 2008, we made a cross-sectional survey of 863 high school students and 2,331 parents of middle and high school students using two anonymously completed questionnaires covering the knowledge of HPV infection and related diseases, and attitudes to vaccinations. The approached schools were a convenience sample of the schools of the greater Milan area, Northern Italy. More mothers than fathers were aware that HPV infection could concern their children (58% vs 53%; p = 0.004) and were favourable towards vaccinating their children against HPV (68% vs 65%; p = 0.03); among the students, more females than males were aware that HPV infection could concern themselves (45% vs 26%; p < 0.001) and would undergo vaccination against HPV (68% vs 40%; p < 0.001). The parents' propensity to vaccinate their children against HPV was significantly associated with professing the Catholic religion (odds ratio - OR = 0.61, 95% confidence interval - CI 0.46-0.82, being atheist), the gender of the offspring (OR = 1.88, 95% CI 1.53-2.30, having at least one daughter), a propensity to vaccinations in general (OR = 23.1, 95% CI 13.7-38.8), a knowledge that HPV vaccine is aimed at preventing cervical cancer (OR = 2.31, 95% CI 1.69-3.16), and an awareness that HPV could affect their own children (OR = 3.52, 95% CI 2.89-4.29). The students who were aware that HPV infection could affect themselves were more in favour of to HPV vaccination, regardless of whether they were male (OR = 5.73, 95% CI 2.85-11.5) or female (OR = 2.39, 95% CI 1.66-3.46). Both students and parents

75 FR 14628 - Pressure Sensitive Plastic Tape From Italy; Determination

Federal Register 2010, 2011, 2012, 2013, 2014

2010-03-26

... Plastic Tape From Italy; Determination On the basis of the record \\1\\ developed in the subject five-year... pressure sensitive plastic tape from Italy would be likely to lead to continuation or recurrence of... Publication 4128 (March 2010), entitled Pressure Sensitive Plastic Tape from Italy: Investigation No. AA1921...

Amyotrophic lateral sclerosis, rural environment and agricultural work in the Local Health District of Ferrara, Italy, in the years 1964-1998.

PubMed

Govoni, Vittorio; Granieri, Enrico; Fallica, Elisa; Casetta, Ilaria

2005-11-01

Previous epidemiological surveys, both analytic and descriptive, in the Local Health District (LHD) of Ferrara, northern Italy, have indicated that rural residence and agricultural work might constitute risk factors for Amyotrophic Lateral Sclerosis (ALS). The present investigation is a demographic survey in the LHD of Ferrara in the years 1964-1998 which aimed to verify whether the level of urbanization and agricultural activities might influence the risk of ALS. Based on the data obtained in a recent incidence study in the LHD of Ferrara which reported a mean annual crude incidence rate of ALS in the years 1964-1998 of 1.63 per 100,000 population (95 % CI 1.31-2.00), it was possible to compare the number of observed ALS cases and the number of expected ALS cases according to the level of urbanization and usual occupation on the basis of the residential and occupational pattern identified in the population of the LHD of Ferrara in the study period under the assumption of a homogeneous distribution of ALS. The present survey identified four different levels of urbanization in the LHD of Ferrara in the study period and for none of them was a difference between the number of observed and expected ALS cases found. Also in the most rural of the four identified levels of urbanization (small villages with an average population in the study period lower than 1,000 inhabitants and scattered houses in the countryside) no difference was found between observed and expected number of ALS cases (observed ALS cases 16, 95% Poisson CI 9.1-25.9, expected ALS cases 18.3). Based on the occupational pattern identified in the population of the LHD of Ferrara in the study period the number of incident cases of ALS whose usual occupation was in agricultural work exceeded the expected number (observed ALS cases 22, 95% Poisson CI 13.8-32.3, expected ALS cases 6.0). The present findings indicate that rural residence itself does not influence the risk of ALS while agricultural activities

Estimation of daily PM10 concentrations in Italy (2006-2012) using finely resolved satellite data, land use variables and meteorology.

PubMed

Stafoggia, Massimo; Schwartz, Joel; Badaloni, Chiara; Bellander, Tom; Alessandrini, Ester; Cattani, Giorgio; De' Donato, Francesca; Gaeta, Alessandra; Leone, Gianluca; Lyapustin, Alexei; Sorek-Hamer, Meytar; de Hoogh, Kees; Di, Qian; Forastiere, Francesco; Kloog, Itai

2017-02-01

Health effects of air pollution, especially particulate matter (PM), have been widely investigated. However, most of the studies rely on few monitors located in urban areas for short-term assessments, or land use/dispersion modelling for long-term evaluations, again mostly in cities. Recently, the availability of finely resolved satellite data provides an opportunity to estimate daily concentrations of air pollutants over wide spatio-temporal domains. Italy lacks a robust and validated high resolution spatio-temporally resolved model of particulate matter. The complex topography and the air mixture from both natural and anthropogenic sources are great challenges difficult to be addressed. We combined finely resolved data on Aerosol Optical Depth (AOD) from the Multi-Angle Implementation of Atmospheric Correction (MAIAC) algorithm, ground-level PM 10 measurements, land-use variables and meteorological parameters into a four-stage mixed model framework to derive estimates of daily PM 10 concentrations at 1-km2 grid over Italy, for the years 2006-2012. We checked performance of our models by applying 10-fold cross-validation (CV) for each year. Our models displayed good fitting, with mean CV-R2=0.65 and little bias (average slope of predicted VS observed PM 10 =0.99). Out-of-sample predictions were more accurate in Northern Italy (Po valley) and large conurbations (e.g. Rome), for background monitoring stations, and in the winter season. Resulting concentration maps showed highest average PM 10 levels in specific areas (Po river valley, main industrial and metropolitan areas) with decreasing trends over time. Our daily predictions of PM 10 concentrations across the whole Italy will allow, for the first time, estimation of long-term and short-term effects of air pollution nationwide, even in areas lacking monitoring data. Copyright © 2016 Elsevier Ltd. All rights reserved.

Detecting Human Presence at the Border of the Northeastern Italian Pre-Alps. 14C Dating at Rio Secco Cave as Expression of the First Gravettian and the Late Mousterian in the Northern Adriatic Region

PubMed Central

Talamo, Sahra; Peresani, Marco; Romandini, Matteo; Duches, Rossella; Jéquier, Camille; Nannini, Nicola; Pastoors, Andreas; Picin, Andrea; Vaquero, Manuel; Weniger, Gerd-Christian; Hublin, Jean-Jacques

2014-01-01

In the northern Adriatic regions, which include the Venetian region and the Dalmatian coast, late Neanderthal settlements are recorded in few sites and even more ephemeral are remains of the Mid-Upper Palaeolithic occupations. A contribution to reconstruct the human presence during this time range has been produced from a recently investigated cave, Rio Secco, located in the northern Adriatic region at the foot of the Carnic Pre-Alps. Chronometric data make Rio Secco a key site in the context of recording occupation by late Neanderthals and regarding the diffusion of the Mid-Upper Palaeolithic culture in a particular district at the border of the alpine region. As for the Gravettian, its diffusion in Italy is a subject of on-going research and the aim of this paper is to provide new information on the timing of this process in Italy. In the southern end of the Peninsula the first occupation dates to around 28,000 14C BP, whereas our results on Gravettian layer range from 29,390 to 28,995 14C years BP. At the present state of knowledge, the emergence of the Gravettian in eastern Italy is contemporaneous with several sites in Central Europe and the chronological dates support the hypothesis that the Swabian Gravettian probably dispersed from eastern Austria. PMID:24759802

Flares in Biopsy-Proven Giant Cell Arteritis in Northern Italy

PubMed Central

Restuccia, Giovanna; Boiardi, Luigi; Cavazza, Alberto; Catanoso, Mariagrazia; Macchioni, Pierluigi; Muratore, Francesco; Cimino, Luca; Aldigeri, Raffaella; Crescentini, Filippo; Pipitone, Nicolò; Salvarani, Carlo

2016-01-01

Abstract This study evaluated the frequency, timing, and characteristics of flares in a large cohort of Italian patients with biopsy-proven giant cell arteritis (GCA) and to identify factors at diagnosis able to predict the occurrence of flares. We evaluated 157 patients with biopsy-proven transmural GCA diagnosed and followed at the Rheumatology Unit of Reggio Emilia Hospital (Italy) for whom sufficient information was available from the time of diagnosis until at least 4 years of follow-up. Fifty-seven patients (36.5%) experienced ≥1 flares. Fifty-one (46.4%) of the 110 total flares (88 relapses and 22 recurrences) were experienced during the first 2 years after diagnosis. The majority of relapses occurred with doses of prednisone ≤ 10 mg/day (82.9%), whereas only 3.4% of relapses occurred for doses ≥ 25 mg/day. Polymyalgia rheumatica (46.5%) and cranial symptoms (41.9%) were the most frequent manifestations at the time of the first relapse. Cumulative prednisone dose during the first year and total cumulative prednisone dose were significantly higher in flaring patients compared with those without flares (7.8 ± 2.4 vs 6.7 ± 2.4 g, P = 0.02; 15.5 ± 8.9 vs 10.0 ± 9.2 g, P = 0.0001, respectively). The total duration of prednisone treatment was longer in flaring patients (58 ± 44 vs 30 ± 30 months, P = 0.0001). Patients with disease flares had at diagnosis more frequently systemic manifestations (P = 0.02) and fever ≥ 38°C (P = 0.02), significantly lower hemoglobin levels (P = 0.05), more frequent presence at temporal artery biopsy (TAB) specimens of giant cells (P = 0.04) and intraluminal acute thrombosis (P = 0.007), and more moderate/severe arterial inflammation (P = 0.009) compared with those without flares. In the multivariate model fever ≥ 38 °C (hazard ratio 2.14; 95% confidence interval, 1.06–4.32, P = 0.03) and the severity of inflammatory infiltrate

Incidence of malignant mesothelioma in Germany 2009-2013.

PubMed

Lehnert, Martin; Kraywinkel, Klaus; Heinze, Evelyn; Wiethege, Thorsten; Johnen, Georg; Fiebig, Julia; Brüning, Thomas; Taeger, Dirk

2017-02-01

The malignant mesothelioma is a rare malignancy and mainly caused by occupational exposure to asbestos. German cancer registries are providing a national database to investigate temporal and regional patterns of mesothelioma incidence. These may be of interest for healthcare planning and for surveillance programs aiming at the formerly exposed workforce. We analyzed population-based incidence data of malignant mesothelioma by site, type, sex, age, as well as district and state of patient's residence. Age-standardized incidence rates (AIRs40+) were calculated according to the European standard population truncated to the age of 40 years and older. We present rates at national, state, and district level and trends of incidence of northern states of Germany. In total, 7,547 malignant mesotheliomas were reported to German cancer registries diagnosed between 2009 and 2013-90% located to the pleura. On average, 1,198 men and 312 women were affected each year. We estimated AIR40+ of 4.77 in 100,000 German men and 0.98 in 100,000 German women. Regional clusters were predominantly located to the seaports of West Germany. The highest regional AIR40+ was 20 per 100,000 men. Corresponding rates in northeast Germany were between 2 and 4 per 100,000 men. Regional clusters of high incidence indicate districts with former shipyards and steel industry, but predominantly in the western part of Germany. The West-to-East difference corresponds to patterns of mortality. Twenty years after banning asbestos in Germany, Bremen and Hamburg are presenting the highest mesothelioma incidence but show steadily decreasing trends.

Vector competence of northern and southern European Culex pipiens pipiens mosquitoes for West Nile virus across a gradient of temperatures.

PubMed

Vogels, C B F; Göertz, G P; Pijlman, G P; Koenraadt, C J M

2017-12-01

In Europe, West Nile virus (WNV) outbreaks have been limited to southern and central European countries. However, competent mosquito vectors and susceptible bird hosts are present in northern Europe. Differences in temperature and vector competence of mosquito populations may explain the absence of WNV outbreaks in northern Europe. The aim of the present study was to directly compare vector competence of northern and southern European Culex pipiens (Cx. p.) pipiens mosquitoes for WNV across a gradient of temperatures. WNV infection and transmission rates were determined for two Cx. p. pipiens populations originating from The Netherlands and Italy, respectively. Mosquitoes were orally exposed by providing an infectious bloodmeal, or by injecting WNV (lineage 2) in the thorax, followed by 14-day incubation at 18, 23, or 28 °C. No differences in infection or transmission rates were found between the Cx. p. pipiens populations with both infection methods, but WNV transmission rates were significantly higher at temperatures above 18 °C. The absence of WNV outbreaks in northern Europe cannot be explained by differences in vector competence between Cx. p. pipiens populations originating from northern and southern Europe. This study suggests that low temperature is a key limiting factor for WNV transmission. © 2017 The Authors. Medical and Veterinary Entomology published by John Wiley & Sons Ltd on behalf of Royal Entomological Society.

Efficacy of different fungicides against Rhizoctonia brown patch and Pythium blight on turfgrass in Italy.

PubMed

Mocioni, M; Titone, P; Garibaldi, A; Gullino, M L

2003-01-01

Brown patch, incited by Rhizoctonia solani Kuhn, and Pythium blight, caused by Pythium spp. are two of the diseases most frequently observed on turfgrass in high maintenance stands, as on golf courses. In such conditions the control strategies, based on chemicals, are particularly difficult due to the scarcity of fungicides registered for turf in Italy. The results obtained in experimental trials carried out to evaluate the efficacy of chemical and biological products against brown patch and Pythium blight are reported. On mature turfgrass, maintained under fairway conditions, azoxystrobin, and trifoxystrobin, not yet registered on turf, were very effective against brown patch. Tebuconazole, applied in three different formulations, was very effective against R. solani, while Trichoderma spp. and azadiractine did not control the pathogen. In greenhouse conditions on Agrostis stolonifera, in the presence of severe disease incidence, due to artificial inoculation, benalaxyl-M satisfactorily controlled Pythium blight; Trichoderma spp. as well as a commercial formulation of T. harzianum, applied one week before the inoculation, were not effective. Among the fungicides not yet registered for use on turfgrass in Italy, metalaxyl-M + mancozeb was effective against Pythium blight.

Cancer incidence in a cohort of asbestos-exposed workers undergoing health surveillance.

PubMed

Barbiero, Fabiano; Zanin, Tina; Pisa, Federica E; Casetta, Anica; Rosolen, Valentina; Giangreco, Manuela; Negro, Corrado; Bovenzi, Massimo; Barbone, Fabio

2018-06-05

To compare a local cohort of 2488 men occupationally exposed to asbestos and enrolled in a public health surveillance program with the 1995-2009 cancer incidence of the general population of Friuli Venezia Giulia (FVG) region, Northeast Italy, we conducted a historical cohort study. Standardized incidence ratios (SIRs), with 95% confidence interval (95% CI), for specific cancer sites were estimated in the cohort and in subgroups of workers employed in shipbuilding between 1974 and 1994. For internal comparisons, we calculated incidence rate ratios (IRRs) for all cancers, lung cancer and mesothelioma, by level of exposure to asbestos and sector of employment adjusted for smoking habits and age at start of follow-up. Among cohort members the SIR was 8.82 (95% CI 5.95-12.61) for mesothelioma and 1.61 (95% CI 1.26-2.04) for lung cancer. In subgroup analyses, the SIR for lung cancer in subjects hired in shipbuilding between 1974 and 1984 was 2.09 (95% CI 1.32-3.13). In the overall cohort, a borderline increased incidence was also found for stomach cancer (SIR = 1.53 95% CI 0.96-2.31). Internal comparisons within the cohort show that among men with high asbestos exposure level the relative risk was almost threefold for lung cancer (IRR = 2.94 95% CI 1.01-8.57). This cohort experienced an excess in the incidence of both mesothelioma and lung cancer, showing increasing incidence rates at higher level of asbestos exposure. For lung cancer, the relative incidence was highest among workers hired in shipbuilding between 1974 and 1984.

Induced abortion and contraception in Italy.

PubMed

Spinelli, A; Grandolfo, M E

1991-09-01

This article discusses the legal and epidemiologic status of abortion in Italy, and its relationship to fertility and contraception. Enacted in May 1978, Italy's abortion law allows the operation to be performed during the 1st 90 days of gestation for a broad range of health, social, and psychological reasons. Women under 18 must receive written permission from a parent, guardian, or judge in order to undergo an abortion. The operation is free of charge. Health workers who object to abortion because of religious or moral reasons are exempt from participating. Regional differences exist concerning the availability of abortion, easy to procure in some places and difficult to obtain in others. After an initial increase following legalization, the abortion rate was 13.5/1000 women aged 15-44 and the abortion ratio was 309/1000 live births -- an intermediate rate and ratio compared to other countries. By the time the Abortion Act of 1978 was adopted, Italy already had one of the lowest fertility levels in Europe. Thus, the legalization of abortion has had no impact on fertility trends. Contrary to initial fears that the legalization of abortion would make abortion a method of family planning, 80% of the women who sought an abortion in 1983-88 were using birth control at the time (withdrawal being the most common method used by this group). In fact, most women who undergo abortions are married, between the ages of 25-34, and with at least one child. Evidence indicates widespread ignorance concerning reproduction. In a 1989 survey, only 65% of women could identify the fertile period of the menstrual cycle. Italy has no sex education in schools or national family planning programs. Compared to most of Europe, Italy still has low levels of reliable contraceptive usage. This points to the need to guarantee the availability of abortion.

Mt. Vesuvius, Italy

NASA Technical Reports Server (NTRS)

2001-01-01

This ASTER image of Mt. Vesuvius Italy was acquired September 26, 2000, and covers an area of 36 by 45 km. Vesuvius overlooks the city of Naples and the Bay of Naples in central Italy. In 79 AD, Vesuvius erupted cataclysmically, burying all of the surrounding cites with up to 30 m of ash. The towns of Pompeii and Herculanaeum were rediscovered in the 18th century, and excavated in the 20th century. They provide a snapshot of Roman life from 2000 years ago: perfectly preserved are wooden objects, food items, and the casts of hundreds of victims. Vesuvius is intensively monitored for potential signs of unrest that could signal the beginning of another eruption. The image is centered at 40.8 degrees north latitude, 14.4 degrees east longitude.

The U.S. science team is located at NASA's Jet Propulsion Laboratory, Pasadena, Calif. The Terra mission is part of NASA's Science Mission Directorate.

Mount Vesuvius, Italy

NASA Technical Reports Server (NTRS)

2002-01-01

This Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) image of Mt. Vesuvius, Italy was acquired September 26, 2000. The full-size false-color image covers an area of 36 by 45 km. Vesuvius overlooks the city of Naples and the Bay of Naples in central Italy. (Popocatepetl and Mount Fuji are other volcanos surrounded by dense urban areas.) In 79 AD, Vesuvius erupted cataclysmically, burying all of the surrounding cites with up to 30 m of ash. The towns of Pompeii and Herculanaeum were rediscovered in the 18th century, and excavated in the 20th century. They provide a snapshot of Roman life from 2000 years ago: perfectly preserved are wooden objects, food items, and the casts of hundreds of victims. Vesuvius is intensively monitored for potential signs of unrest that could signal the beginning of another eruption. Image courtesy NASA/GSFC/MITI/ERSDAC/JAROS, and U.S./Japan ASTER Science Team

Incidence of amyotrophic lateral sclerosis in three counties in western Washington state.

PubMed

McGuire, V; Longstreth, W T; Koepsell, T D; van Belle, G

1996-08-01

We conducted a population-based study of amyotrophic lateral sclerosis (ALS) in King, Pierce, and Snohomish counties in western Washington state. Between April 1, 1990 and March 31, 1995, neurologists diagnosed 235 patients with ALS, including 127 men (54%) and 108 women (46%). The incidence rate, age-adjusted to the 1990 total U.S. population, was higher for men at 2.1 per 100,000 per year (95% CI, 1.3 to 2.9) than for women at 1.9 (95% CI, 1.1, 2.7) and increased with age for both men and women. These incidence rates are consistent with other studies from northern latitudes.

Aquifer recharge from infiltration basins in a highly urbanized area: the river Po Plain (Italy)

NASA Astrophysics Data System (ADS)

Masetti, M.; Nghiem, S. V.; Sorichetta, A.; Stevenazzi, S.; Santi, E. S.; Pettinato, S.; Bonfanti, M.; Pedretti, D.

2015-12-01

Due to the extensive urbanization in the Po Plain in northern Italy, rivers need to be managed to alleviate flooding problems while maintaining an appropriate aquifer recharge under an increasing percentage of impermeable surfaces. During the PO PLain Experiment field campaign in July 2015 (POPLEX 2015), both active and under-construction infiltration basins have been surveyed and analyzed to identify appropriate satellite observations that can be integrated to ground based monitoring techniques. A key strategy is to have continuous data time series on water presence and level within the basin, for which ground based monitoring can be costly and difficult to be obtained consistently.One of the major and old infiltration basin in the central Po Plain has been considered as pilot area. The basin is active from 2003 with ground based monitoring available since 2009 and supporting the development of a calibrated unsaturated-saturated two-dimensional numerical model simulating the infiltration dynamics through the basin.A procedure to use satellite data to detect surface water change is under development based on satellite radar backscatter data with an appropriate incidence angle and polarization combination. An advantage of satellite radar is that it can observe surface water regardless of cloud cover, which can be persistent during rainy seasons. Then, the surface water change is correlated to the reservoir water stage to determine water storage in the basin together with integrated ground data and to give quantitative estimates of variations in the local water cycle.We evaluated the evolution of the infiltration rate, to obtain useful insights about the general recharge behavior of basins that can be used for informed design and maintenance. Results clearly show when the basin becomes progressively clogged by biofilms that can reduce the infiltration capacity of the basin by as much as 50 times compared to when it properly works under clean conditions.

Multidisciplinary approach to evaluate flood damage for residential buildings: first results in Northern Italy

NASA Astrophysics Data System (ADS)

Luino, Fabio

2015-04-01

Flooding is the most common natural instability process in Italy. Flood damage are the results of land-use planning policies which, starting chiefly from the late 1950s and early 1960s, did not take into account the geomorphologic-hydraulic characteristics of an area or the its historical data on past flood events. Historically, compared to other areas, riverside property has always been less valuable. Unfortunately, year after year, even areas of high recreational and environmental value were intensely urbanized despite their being exposed to the threat of flooding. As the number of residential dwellings, infrastructure and industrial buildings increased, what was originally a hazard became a risk. For each flood event, the damage depends on the specific land-use of the area and subsequently on the elements at risk in the area involved and its vulnerability, expressed as a percentage of the element that has actually been lost during the event. This is why a comprehensive knowledge of the area it is so important for conducting a detailed survey of an area's structures and infrastructure and to evaluate the degree of vulnerability. This paper presents first results in Italy of the European Project called DAMAGE, the first attempt by the civil protection agencies of several European Union member states to devise a common methodology for the assessment of damage caused by natural or anthropic disasters. The main objective was to create an initial tool for practical and immediate application by civil protection agencies and local governments, to assess damage in a multidimensional perspective that takes into account infrastructure, the economy, the environment and social problems. Within the framework of a broad-based project for the evaluation and collection of reports on damage caused by floods, the CNR-IRPI of Turin and Regione Lombardia have directed attention to the town of Cittiglio (province of Varese), which was struck by severe flash flood in May 2002. One of

[Analysis of human cyst echinococcosis in a northern Chilean region from 2008 to 2012].

PubMed

Soto-Aguilar, Andrea; Junod, Tania; Campillay, Mauricio; Acosta-Jamett, Gerardo; Landaeta-Aqueveque, Carlos

2017-05-01

The Coquimbo Region in Chile has the highest incidence of hydatidosis in central and northern Chile. To analyze the incidence of human cystic echinococcosis (CE) in the Coquimbo Region between 2008 and 2012. Official records of reported cases were analyzed. The association of the location, age and sex with the presence/absence of CE was analyzed by means of logistic regressions. The incidence was reported as cases per 100,000 inhabitants. The mean annual incidence was 2.6 cases per 100,000 inhabitants, which ranged from 3.1 (2010) to 1.9 (2012) cases. The districts with higher incidence were Punitaqui (21.2 cases), Paihuano (9 cases), Rio Hurtado (8 cases), Canela (8.1 cases), Monte Patria (7.9 cases), Vicuña (6.9 cases) and Combarbalá (6.9 cases). The incidence in these locations was significantly higher than elsewhere in the region. Males had a significantly higher incidence than females (3.3 and 1.8 respectively). Incidence increased significantly with age, notably increasing after 45 years of age. Rural locations had the highest incidences of CE in the Coquimbo Region. The disease was reported more commonly in adults and mainly in men.

Epidemiological survey of multiple sclerosis in the provinces of Reggio Emilia and Modena, Italy.

PubMed

Guidetti, D; Cavalletti, S; Merelli, E; Zanoni, P; Simonazzi, P; Sola, P; Solimé, F

1995-01-01

We present the results of an epidemiological survey on MS conducted in the provinces of Reggio Emilia and Modena (4,980 km2) from 1970 to 1990. The population increased from 943,182 residents in 1970 to 1,024,223 in 1990, with an average population during the period of the survey of 993,056. The mean annual incidence was 1.59 cases/100,000 inhabitants (c.i. 95% 1.42-1.78). The prevalence as of December 31, 1990, was 39.44/100,000 inhabitants. Our study is a further demonstration that Italy is a high-risk zone for this disease, and also demonstrates the possibility of carrying out reliable epidemiological surveys even over extensive territories.

Location Capability and Site Characterization Installing a Borehole VBB Seismometer: the OGS Experience in Ferrara (Italy)

NASA Astrophysics Data System (ADS)

Pesaresi, D.; Barnaba, C.

2014-12-01

The Centro di Ricerche Sismologiche (CRS, Seismological Research Centre) of the Istituto Nazionale di Oceanografia e di Geofisica Sperimentale (OGS, Italian National Institute for Oceanography and Experimental Geophysics) in Udine (Italy) after the strong earthquake of magnitude M=6.4 occurred in 1976 in the Italian Friuli-Venezia Giulia region, started to operate the Northeastern Italy Seismic Network: it currently consists of 19 very sensitive broad band and 17 simpler short period seismic stations, all telemetered to and acquired in real time at the OGS CRS data centre in Udine. The southwestern edge of the OGS seismic network stands on the Po alluvial basin: earthquake localization and characterization in this area is affected by the presence of soft alluvial deposits. Following the ML=5.9 earthquake that struck the Emilia region around Ferrara in Northern Italy on May 20, 2012, a cooperation of Istituto Nazionale di Geofisica e Vulcanologia, OGS, the Comune di Ferrara and the University of Ferrara lead to the reinstallation of a previously existing very broad band (VBB) borehole seismic station in Ferrara and to the deployment of a temporary seismographic network consisting of eight portable seismological stations, to record the local earthquakes that occurred during the seismic sequence. The aim of the OGS intervention was on one hand to extend its real time seismic monitoring capabilities toward South-West, including Ferrara and its surroundings, and on the other hand to evaluate seismic site responses in the area. We will introduce details of the Ferrara VBB borehole station and the OGS temporary seismographic network configuration and installation. We will then illustrate the location capability performances, and finally we will shortly describe seismic site characterization with surface/borehole comparisons in terms of seismic noise, site amplification and resonance frequencies.

Carbon cycle perturbations recorded by δ13C of bulk organic matter: the Carnian Pluvial Event in the Dolomites, northern Italy

NASA Astrophysics Data System (ADS)

Preto, Nereo; Breda, Anna; Dal Corso, Jacopo; Rigo, Manuel; Roghi, Guido; Spötl, Christoph

2015-04-01

A period of increased rainfall occurred in the Carnian (Late Triassic), known as Carnian Pluvial Event (CPE), which is evidenced by major lithological changes in continental and marine successions at tropical latitudes. Increased continental weathering and erosion led to the supply of large amounts of siliciclastics into the marginal basins of the Tethys. Seawater anoxia is also observed locally in semi-restricted basins. Simultaneously, microbial factories on high-relief carbonate platforms were replaced by metazoan factories, forming low-relief carbonate ramps and mixed low-gradient shelves. This environmental change has been shown to be closely associated with a negative carbon isotope excursion. A negative δ13C shift is recorded by bulk organic matter in the Milieres section (central Dolomites) and parallels a coeval excursion in carbon-isotope records of higher plant and marine algal biomarker, thus testifying a global change in the isotopic composition of carbon dioxide in the atmosphere and of dissolved inorganic carbon (DIC) in the ocean. This isotopic excursion was identified in organic carbon records throughout the western Tethys, but so far could not be reproduced convincingly using carbon isotope records from carbonate. A long carbon isotope record was produced from bulk organic matter of the early to late Carnian Milieres - Dibona section in the Dolomites, northern Italy. Carbon isotope analyses of carbonate (limestone and dolomite) were also obtained. This new carbon isotope record illustrates the structure of this complex carbon cycle perturbation related to the CPE. But while sharp carbon isotope oscillations are evident in the bulk organic carbon record, there is no evidence of a similar pattern in carbonate record. It can be shown that the carbon isotope record of carbonates is influenced by fractionation and diagenetic processes that completely obliterated the original δ13C signal. We conclude that the Carnian carbonates of the Dolomites do not

Large-Scale Assessments and Educational Policies in Italy

ERIC Educational Resources Information Center

Damiani, Valeria

2016-01-01

Despite Italy's extensive participation in most large-scale assessments, their actual influence on Italian educational policies is less easy to identify. The present contribution aims at highlighting and explaining reasons for the weak and often inconsistent relationship between international surveys and policy-making processes in Italy.…

Seismic Investigations of the Murci Geothermal Field (Southern Tuscany, Italy): Preliminary Results

NASA Astrophysics Data System (ADS)

Riedel, M.; Alexandrakis, C.; Buske, S.

2013-12-01

analysis which will reveal more details about the structures of the Murci area. Batini, F. et al., 2003: Geological features of Larderello-Travale and Mt. Amiata geothermal areas (southern Tuscany, Italy), Episodes, 26, 239-244. Brogi, A., 2008. The structure of the Monte Amiata volcano-geothermal area (Northern Apennines, Italy): Neogene-Quaternary compression versus extension, Int J Earth Sci (Geol Rundsch) (2008) 97:677-703 Dini, I. et al., 2010. Geological Evaluation of the Base of the Mt. Amiata Volcanic Complex (Tuscany, Italy), Procedings World Geothermal Congress 2010, Bali, Indonesia, April 2010.

Prevalence and Risk Factors of Infertility at a Rural Site of Northern China

PubMed Central

Zheng, Liqiang; Tan, Jichun

2016-01-01

Objective To investigate and analyze prevalence and risk factors of infertility at a representative rural site of Northern China. Method This is a cross-sectional study. We conducted a face-to-face questionnaire survey from July 2014 to October 2014 involving 5,131 women who were at childbearing age in Suizhong, a medium-sized, representative county located in Northern China. Finally, data from 4,232 valid questionnaires were analyzed. Definition Infertility is defined as the failure to achieve a clinical pregnancy after 12 months or more of regularly unprotected sexual intercourse. Results Infertility prevalence in Suizhong County was 13.09% (95% CI, 12.09%-14.1%), of which the primary infertility incidence was 0.99% (95% CI, 0.72%-1.34%), and the secondary infertility incidence was 12.10% (95% CI, 11.13%-13.12%). For women, the infertility incidence of underweight women (Body Mass Index, BMI<18.5 kg/m2) was 1.5-fold higher than that of women with moderate BMI (18.5–24.9 kg/m2). The infertility incidence of women with little exercise was 4 times more than that of women with regular exercise, and 2 times more than that of women with heavy exercise. The group with moderate menstrual flow had the lowest prevalence of infertility, while both scant and excessive menstruation led to increased infertility incidence. Number of pregnancies (OR = 0.63; 95% CI, 0.51–0.79) was a protective factor for infertility, while the number of abortions (OR = 2.15; 95% CI, 1.58–2.93) was a risk factor for infertility. For men, those who stayed up late at night more than 3 times per week showed a significantly higher infertility incidence. Men who engaged in occupations with high-temperature working environment also suffered from an infertility incidence of about four times more than the others. Conclusions We found significant association between women's infertility incidence with their BMI, state of exercise, amount of menstrual flow, number of pregnancies and number of abortions

Systematic review: gastric cancer incidence in pernicious anaemia.

PubMed

Vannella, L; Lahner, E; Osborn, J; Annibale, B

2013-02-01

Pernicious anaemia (PA) has an increased risk for gastric cancer (GC). It is not established whether PA patients need to undergo endoscopic/histological follow-up. To provide a systematic overview of the literature on PA and the development of gastric cancer, to estimate the gastric cancer incidence-rate. According to PRISMA, we identified studies on PA patients reporting the incidence of gastric cancer. Quality of studies was evaluated using the Newcastle-Ottawa Quality Assessment Scale. Meta-analysis on annual gastric cancer incidence rates was performed. Twenty-seven studies met eligibility criteria. 7 studies were of high, 6 of medium, 10 of low and 4 of very low quality. Gastric cancer incidence-rates ranged from 0% to 0.2% per person-years in 7 American, from 0% to 0.5% in 2 Asiatic, from 0% to 1.2% in 11 Northern European studies and from 0% to 0.9% in 7 studies from other European countries. The incidence-rates of gastric cancer ranged from 0% to 1.2% per person-years in studies which used gastroscopy, from 0.1% to 0.9% in those based on International Classification of Disease. Heterogeneity between studies was not statistically significant at the 5% level (Chi-squared test = 17.9, P = 0.08). The calculated pooled gastric cancer incidence-rate was 0.27% per person-years. Meta-analysis showed overall gastric cancer relative risk in PA as 6.8 (95% CI: 2.6-18.1). This systematic review shows a pooled gastric cancer incidence-rate in pernicious anaemia of 0.27% per person-years and an estimated nearly sevenfold relative risk of gastric cancer in pernicious anaemia patients. Further high quality studies are needed to confirm this higher risk. © 2012 Blackwell Publishing Ltd.

Sero-epidemiology of hepatitis B markers in the population of Tuscany, Central Italy, 20 years after the implementation of universal vaccination

PubMed Central

Boccalini, Sara; Pellegrino, Elettra; Tiscione, Emila; Pesavento, Giovanna; Bechini, Angela; Levi, Miriam; Rapi, Stefano; Mercurio, Stefano; Mannelli, Francesco; Peruzzi, Marta; Berardi, Cesare; Bonanni, Paolo

2013-01-01

Italy was one of the first industrialized countries to introduce a program of universal vaccination against hepatitis B in 1991. Twenty years later we verified the impact of universal immunisation on the epidemiology of hepatitis B infection by analyzing the prevalence of specific viral markers (anti-HBs, anti-HBc and HBsAg). The ELISA tests were performed on residual blood samples collected by 0.05% of the resident population aged 1-50 years in Tuscany (Italy). About 63% of subjects aged < 30 years were anti-HBs positive compared to about 25% in older subjects, without differences between genders. About 22% of subjects over 40 years were anti-HBc-positive compared to 5% in the younger age groups. The number of HBsAg-positive subjects was almost 10 fold higher in the unvaccinated age groups than in the cohorts involved in the universal vaccination program. The results of our study show the persisting high anti-HBs reactivity in vaccinated cohorts, while HBV markers related to natural exposure or persistent infection remain remarkably higher in older age groups. This sero-epidemiological study supports with prevalence data the downward incidence trend of acute hepatitis B highlighted by epidemiological surveillance systems, and corroborates the forecast for elimination of hepatitis B in Italy in a few decades. PMID:23354158

Lymphohaematopoietic system cancer incidence in an urban area near a coke oven plant: an ecological investigation

PubMed Central

Parodi, S; Vercelli, M; Stella, A; Stagnaro, E; Valerio, F

2003-01-01

Aims: To evaluate the incidence risk of lymphohaematopoietic cancers for the 1986–94 period in Cornigliano, a district of Genoa (Italy), where a coke oven is located a few hundred metres from the residential area. Methods: The whole of Genoa and one of its 25 districts (Rivarolo) were selected as controls. The trend of risk around the coke oven was evaluated via Stone's method, while the geographic pattern of such risks across the Cornigliano district was evaluated by computing full Bayes estimates of standardised incidence ratio (FBE-SIR). Results: In males, elevated relative risks (RR) were observed for all lymphohaematopoietic cancers (RR 1.7 v Rivarolo and 1.6 v Genoa), for NHL (RR 2.4 v Rivarolo and 1.7 v Genoa), and for leukaemia (RR 2.4 v Rivarolo and 1.9 v Genoa). In females, statistically non-significant RR were observed. In males no excess of risk was found close to the coke oven. In females, a rising risk for NHL was observed approaching the plant, although statistical significance was not reached, while the risk for leukaemia was not evaluable due to the small number of cases. Analysis of the geographic pattern of risk suggested the presence of a cluster of NHL in both sexes in the eastern part of the district, where a foundry had been operational until the early 1980s. A cluster of leukaemia cases was observed in males in a northern part of the area, where no major sources of benzene seemed to be present. Conclusions: The estimated risks seem to be slightly or not at all related to the distance from the coke oven. The statistically significant higher risks observed in males for NHL and leukaemia, and the clusters of leukaemia in males and of NHL in both sexes deserve further investigations in order to trace the exposures associated with such risks. PMID:12598665

Knowledge, attitudes, beliefs and practices of construction workers towards tetanus vaccine in Northern Italy.

PubMed

Riccò, Matteo; Cattani, Silvia; Veronesi, Licia; Colucci, Maria Eugenia

2016-12-07

Construction workers (CWs) are both more exposed to tetanus and at higher risk to be inadequately immunized. Our aim was to evaluate tetanus immunization status and knowledge/attitudes towards tetanus vaccination in CWs in Italy. In this field report, the immunization status of 554 unskilled CWs (i.e. labourers). Immunization status was assessed recalling immunization booklets/certificates. Attitudes and knowledge were collected through a standardized questionnaire. In 240/554 CWs, immunization status was inadequate/not documented: in 184 subjects (33.2%), the last vaccination shot was older than 10 years, whereas basal immunization was incomplete in 20 cases, more frequently in foreign-born people (FBP) than in Italian born (IBP) (OR=7.116). In 198 cases (35.7%), an Occupational Physician (OPh) performed last booster, usually with monovalent (T, n=173) vaccine. The main reason for inadequate immunization was having forgotten the periodic booster (148/554; 26.7%), whereas 42 subjects (7.6%) deliberately avoided tetanus vaccine because of personal/religious beliefs, more frequently in FBP than in IBP (OR=3.182). In summary, the prevalence of inadequate immunization status was relatively high (43.4%): the high prevalence of "forgotten boosters" enlightens the key role of OPh in recalling and promoting vaccination policies. Moreover, the inappropriate use of Td vaccine points out the opportunity for educational campaigns in OPh.

Investigating source directivity for the 2012 Ml5.9 Emilia (Northern Italy) earthquake by jointly using High-rate GPS and Strong motion data

NASA Astrophysics Data System (ADS)

Avallone, A.; Herrero, A.; Latorre, D.; Rovelli, A.; D'Anastasio, E.

2012-12-01

On May, 20th 2012, the Ferrara and Modena provinces (Emilia Romagna, Northern Italy) were struck by a moderate magnitude earthquake (Ml 5.9). The focal mechanism is consistent with a ~E-W-striking thrust fault. The mainshock was recorded by 29 high-rate sampling (1-Hz) continuous GPS (HRGPS) stations belonging to scientific or commercial networks and by 55 strong motion (SM) stations belonging to INGV (Istituto Nazionale di Geofisica e Vulcanologia) and RAN (Rete Accelerometrica Nazionale) networks, respectively. The spatial distribution of both HRGPS and SM stations with respect to the mainshock location allows a satisfactory azimuthal coverage of the area. To investigate directivity effects during the mainshock occurrence, we analyze the spatial variation of the peak ground displacement (PGD) measured either for HRGPS or SM sites, using different methods. For each HRGPS and SM site, we rotated the horizontal time series to the azimuth direction and we estimated the GPS-related and the SM-related peak ground displacement (G-PGD and S-PGD, respectively) retrieved by transverse component. However, in contrast to GPS displacements, the double integration of the SM data can be affected by the presence of drifts and, thus, they have to be corrected by quasi-manual procedures. To more properly compare the G-PGDs to the S-PGDs, we used the response spectrum. A response spectrum is simply the response of a series of oscillators of varying natural frequency, that are forced into motion by the same input. The asymptotic value of the displacement response spectrum is the peak ground displacement. Thus, for each HRGPS and SM site, we computed the value of this asymptotic trend (G-PGDrs and S-PGDrs, respectively). This method allows simple automatic procedures. The consistency of the PGDs derived from HRGPS and SM is also evaluated for sites where the two instruments are collocated. The PGDs obtained by the two different methods and the two different data types suggest a

Occurrence and molecular characterisation of Vibrio parahaemolyticus in crustaceans commercialised in Venice area, Italy.

PubMed

Caburlotto, Greta; Suffredini, Elisabetta; Toson, Marica; Fasolato, Luca; Antonetti, Paolo; Zambon, Michela; Manfrin, Amedeo

2016-03-02

Infections due to the pathogenic human vibrios, Vibrio parahaemolyticus, Vibrio cholerae and Vibrio vulnificus, are mainly associated with consumption of raw or partially cooked bivalve molluscs. At present, little is known about the presence of Vibrio species in crustaceans and the risk of vibriosis associated with the consumption of these products. The aim of the present study was to evaluate the prevalence and concentration of the main pathogenic Vibrio spp. in samples of crustaceans (n=143) commonly eaten in Italy, taking into account the effects of different variables such as crustacean species, storage conditions and geographic origin. Subsequently, the potential pathogenicity of V. parahaemolyticus strains isolated from crustaceans (n=88) was investigated, considering the classic virulence factors (tdh and trh genes) and four genes coding for relevant proteins of the type III secretion systems 2 (T3SS2α and T3SS2β). In this study, the presence of V. cholerae and V. vulnificus was never detected, whereas 40 samples (28%) were positive for V. parahaemolyticus with an overall prevalence of 41% in refrigerated products and 8% in frozen products. The highest prevalence and average contamination levels were detected in Crangon crangon (prevalence 58% and median value 3400 MPN/g) and in products from the northern Adriatic Sea (35%), with the samples from the northern Venetian Lagoon reaching a median value of 1375 MPN/g. While genetic analysis confirmed absence of the tdh gene, three of the isolates contained the trh gene and, simultaneously, the T3SS2β genes. Moreover three possibly clonal tdh-negative/trh-negative isolates carried the T3SS2α apparatus. The detection of both T3SS2α and T3SS2β apparatuses in V. parahaemolyticus strains isolated from crustaceans emphasised the importance of considering new genetic markers associated with virulence besides the classical factors. Moreover this study represents the first report dealing with Vibrio spp. in

Molecular detection and phylogenetic analysis of hepatitis E virus strains circulating in wild boars in south-central Italy.

PubMed

Aprea, G; Amoroso, M G; Di Bartolo, I; D'Alessio, N; Di Sabatino, D; Boni, A; Cioffi, B; D'Angelantonio, D; Scattolini, S; De Sabato, L; Cotturone, G; Pomilio, F; Migliorati, G; Galiero, G; Fusco, G

2018-02-01

Hepatitis E virus (HEV) is a zoonotic pathogen with a worldwide distribution, and infects several mammalian species, including pigs and wild boars, which are recognized as its natural reservoirs. The virus causes a usually self-limiting liver disease with a mortality rate generally below 1%, although mortality rates of 15%-25% have been recorded in pregnant woman. Chronic infections can also occur. The prevalence of HEV has been extensively studied in wild boars and pigs in northern Italy, where intensive pig herds are predominantly located. In contrast, few data have been collected in south-central Italy, where small pig herds are surrounded by large regional parks populated with heterogeneous wild fauna. In this study, 291 liver samples from wild boars caught in south-central Italy were analysed with the molecular detection of viral RNA. Our results confirm the circulation of HEV in these animals, with a mean prevalence of 13.7% (40 of 291). A nucleotide sequence analysis showed that the HEV strains were highly conserved within the same geographic areas. The wild boar HEV strains belonged to the HEV-3c subtype, which is frequently described in wild boars, and to an uncommon undefined subtype (HEV-3j-like).The viral prevalence detected is concerning because it could represent a potential risk to hunters, meat workers and consumers of wild boar liver and derivative products. The hypothesized inter-species transmission of HEV to pigs and the possibility that the virus maintains its virulence in the environment and the meat chain also present potential risks to human health, and warrant further investigations in the near future. © 2017 Blackwell Verlag GmbH.

Spatial and temporal patterns of locally-acquired dengue transmission in northern Queensland, Australia, 1993-2012.

PubMed

Naish, Suchithra; Dale, Pat; Mackenzie, John S; McBride, John; Mengersen, Kerrie; Tong, Shilu

2014-01-01

Dengue has been a major public health concern in Australia since it re-emerged in Queensland in 1992-1993. We explored spatio-temporal characteristics of locally-acquired dengue cases in northern tropical Queensland, Australia during the period 1993-2012. Locally-acquired notified cases of dengue were collected for northern tropical Queensland from 1993 to 2012. Descriptive spatial and temporal analyses were conducted using geographic information system tools and geostatistical techniques. 2,398 locally-acquired dengue cases were recorded in northern tropical Queensland during the study period. The areas affected by the dengue cases exhibited spatial and temporal variation over the study period. Notified cases of dengue occurred more frequently in autumn. Mapping of dengue by statistical local areas (census units) reveals the presence of substantial spatio-temporal variation over time and place. Statistically significant differences in dengue incidence rates among males and females (with more cases in females) (χ(2) = 15.17, d.f.  = 1, p<0.01). Differences were observed among age groups, but these were not statistically significant. There was a significant positive spatial autocorrelation of dengue incidence for the four sub-periods, with the Moran's I statistic ranging from 0.011 to 0.463 (p<0.01). Semi-variogram analysis and smoothed maps created from interpolation techniques indicate that the pattern of spatial autocorrelation was not homogeneous across the northern Queensland. Tropical areas are potential high-risk areas for mosquito-borne diseases such as dengue. This study demonstrated that the locally-acquired dengue cases have exhibited a spatial and temporal variation over the past twenty years in northern tropical Queensland, Australia. Therefore, this study provides an impetus for further investigation of clusters and risk factors in these high-risk areas.

Derivation of risk indices and analysis of variablility for the management of incidents involving the transport of nuclear materials in the Northern Seas.

PubMed

Brown, J; Hosseini, A; Karcher, M; Kauker, F; Dowdall, M; Schnur, R; Strand, P

2016-04-15

The transport of nuclear or radioactive materials and the presence of nuclear powered vessels pose risks to the Northern Seas in terms of potential impacts to man and environment as well socio-economic impacts. Management of incidents involving actual or potential releases to the marine environment are potentially difficult due to the complexity of the environment into which the release may occur and difficulties in quantifying risk to both man and environment. In order to address this, a state of the art oceanographic model was used to characterize the underlying variability for a specific radionuclide release scenario. The resultant probabilistic data were used as inputs to transfer and dose models providing an indication of potential impacts for man and environment This characterization was then employed to facilitate a rapid means of quantifying risk to man and the environment that included and addressed this variability. The radionuclide specific risk indices derived can be applied by simply multiplying the reported values by the magnitude of the source term and thereafter summing over all radionuclides to provide an indication of total risk. Copyright © 2016. Published by Elsevier Ltd.

Urban air pollution and respiratory emergency visits at pediatric unit, Reggio Emilia, Italy.

PubMed

Bedeschi, Emanuela; Campari, Cinzia; Candela, Silvia; Collini, Giorgia; Caranci, Nicola; Frasca, Gabriella; Galassi, Claudia; Francesca, Gabriella; Vigotti, Maria Angela

2007-02-01

Short-term effects of air pollution on daily mortality and hospital admissions for respiratory causes are well documented. Few studies, however, explore the association between exposure to air pollution and daily emergency room visits for respiratory disorders, particularly in Italy and particularly among children as a susceptible population. A time-series analysis was conducted to explore the short-term association between air pollutants (PM10, total suspended particulates [TSP], NO2, SO2, CO, O3) and pediatric emergency room (ER) visits in a small city of northern Italy, Reggio Emilia, during the period 03/01/2001-03/31/2002. There were 1051 ER visits included in the study. Data were analyzed using generalized additive models (GAM), adjusting for various confounding variables, including temperature, humidity, and pollens (Graminaceae). The analyses were also stratified according to the nationality of children (Italians and foreigners). In single-pollutant models, the strongest associations were observed at lag 3 for a 10-microg/m3 increase of TSP (2.7% increase in ER, 95% CI 0.7-4.6) and PM10 (3.0% increase, 95% CI 0.4-5.7), and at lag 4 for a 10-microg/m3 increase of NO2 (11.0% increase in ER, 95% CI 3.6-18.8). At lag 3, the percentage increase in ER visits is similar for the 2 groups of children (Italians and foreigners) for TSP and PM10. The results of the study support the findings that air pollution is a relevant determinant of deterioration of respiratory health among children.

Incidence of aneurysmal subarachnoid hemorrhage in Shimokita, Japan, from 1989 to 1998.

PubMed

Ohkuma, Hiroki; Fujita, Seiichiroh; Suzuki, Shigeharu

2002-01-01

The incidence of subarachnoid hemorrhage (SAH) has been investigated in many studies. A recent study in Izumo, Japan, indicates that the incidence of SAH is as high as that in Finland. The purpose of this study was to confirm the high incidence of SAH in Japan. The incidence rate of SAH was investigated from 1989 through 1998 in the Shimokita peninsula, which is a clearly defined closed-boundary area in northern Japan with a population of 89 991. The registration was based on the complete referral system of SAH patients. All cases suspected of SAH underwent CT scan, and the images were referred to stroke specialists. The moribund cases and dead-on-arrival cases suspected of SAH also underwent CT scan. From 1989 through 1998, 198 cases were diagnosed as having aneurysmal SAH. Out of these, 26 cases were moribund or dead when the initial CT scan was performed. The age-adjusted annual incidence of SAH was 21 per 100 000 person-years. The age and sex distribution of the cases indicated that the incidence plateaued after age 45 in men and the incidence increased after age 45 and reached the peak after 75 years in women. The high incidence of SAH in Japan is confirmed. The incidence of SAH obtained in this study is near to that of the Izumo study, of which the size of the geographic region and denominator and diagnostic criteria were similar to this study.

The global incidence of lip, oral cavity, and pharyngeal cancers by subsite in 2012.

PubMed

Shield, Kevin D; Ferlay, Jacques; Jemal, Ahmedin; Sankaranarayanan, Rengaswamy; Chaturvedi, Anil K; Bray, Freddie; Soerjomataram, Isabelle

2017-01-01

By using data from the International Agency for Research on Cancer publication Cancer Incidence in 5 Continents and GLOBOCAN, this report provides the first consolidated global estimation of the subsite distribution of new cases of lip, oral cavity, and pharyngeal cancers by country, sex, and age for the year 2012. Major geographically based, sex-based, and age-based variations in the incidence of lip, oral cavity, and pharyngeal cancers by subsite were observed. Lip cancers were highly frequent in Australia (associated with solar radiation) and in central and eastern Europe (associated with tobacco smoking). Cancers of the oral cavity and hypopharynx were highly common in south-central Asia, especially in India (associated with smokeless tobacco, bidi, and betel-quid use). Rates of oropharyngeal cancers were elevated in northern America and Europe, notably in Hungary, Slovakia, Germany, and France and were associated with alcohol use, tobacco smoking, and human papillomavirus infection. Nasopharyngeal cancers were most common in northern Africa and eastern/southeast Asia, indicative of genetic susceptibility combined with Epstein-Barr virus infection and early life carcinogenic exposures (nitrosamines and salted foods). The global incidence of lip, oral cavity, and pharyngeal cancers of 529,500, corresponding to 3.8% of all cancer cases, is predicted to rise by 62% to 856,000 cases by 2035 because of changes in demographics. Given the rising incidence of lip, oral cavity, and pharyngeal cancers and the variations in incidence by subsites across world regions and countries, there is a need for local, tailored approaches to prevention, screening, and treatment interventions that will optimally reduce the lip, oral cavity, and pharyngeal cancer burden in future decades. CA Cancer J Clin 2017;67:51-64. © 2016 American Cancer Society. © 2016 American Cancer Society.

Northern Studies at Northern Universities.

ERIC Educational Resources Information Center

Northern Review: A Multidisciplinary Journal of the Arts and Social Sciences of the North, 1994

1994-01-01

Describes college programs and research projects focused on the Arctic, northern studies, or northern concerns at Athabasca University (Alberta), the University of British Columbia, the University of Alaska Anchorage, the University of Alaska Fairbanks, the Scott Polar Institute at the University of Cambridge (England), and Kent State University…

Syndepositional tectonics recorded by soft-sediment deformation and liquefaction structures (continental Lower Permian sediments, Southern Alps, Northern Italy): Stratigraphic significance

NASA Astrophysics Data System (ADS)

Berra, F.; Felletti, F.

2011-04-01

The Lower Permian succession of the Central Southern Alps (Lombardy, Northern Italy) was deposited in fault-controlled continental basins, probably related to transtensional tectonics. We focussed our study on the stratigraphic record of the Lower Permian Orobic Basin, which consists of a 1000 m thick succession of prevailing continental clastics with intercalations of ignimbritic flows and tuffs (Pizzo del Diavolo Formation, PDV) resting on the underlying prevailing pyroclastic flows of the Cabianca Volcanite. The PDV consists of a lower part (composed of conglomerates passing laterally to sandstones and distally to silt and shales), a middle part (pelitic, with carbonates) and an upper part (alternating sandstone, silt and volcanic flows). Syndepositional tectonics during the deposition of the PDV is recorded by facies distribution, thickness changes and by the presence of deformation and liquefaction structures interpreted as seismites. Deformation is recorded by both ductile structures (ball-and-pillow, plastic intrusion, disturbed lamination, convolute stratification and slumps) and brittle structures (sand dykes and autoclastic breccias). Both the sedimentological features and the geodynamic setting of the depositional basin confidently support the interpretation of the described deformation features as related to seismic shocks. The most significant seismically-induced deformation is represented by a slumped horizon (about 4 m thick on average) which can be followed laterally for more than 5 km. The slumped bed consists of playa-lake deposits (alternating pelites and microbial carbonates, associated with mud cracks and vertebrate tracks). The lateral continuity and the evidence of deposition on a very low-angle surface along with the deformation/liquefaction of the sediments suggest that the slump was triggered by a high-magnitude earthquake. The stratigraphic distribution of the seismites allows us to identify time intervals of intense seismic activity

Hydrothermal Upflow, Serpentinization and Talc Alteration Associated with a High Angle Normal Fault Cutting an Oceanic Detachment, Northern Apennines, Italy

NASA Astrophysics Data System (ADS)

Alt, J.; Crispini, L.; Gaggero, L.; Shanks, W. C., III; Gulbransen, C.; Lavagnino, G.

2017-12-01

Normal faults cutting oceanic core complexes are observed at the seafloor and through geophysics, and may act as flow pathways for hydrothermal fluids, but we know little about such faults in the subsurface. We present bulk rock geochemistry and stable isotope data for a fault that acted as a hydrothermal upflow zone in a seafloor ultramafic-hosted hydrothermal system in the northern Apennines, Italy. Peridotites were exposed on the seafloor by detachment faulting, intruded by MORB gabbros, and are overlain by MORB lavas and pelagic sediments. North of the village of Reppia are fault shear zones in serpentinite, oriented at a high angle to the detachment surface and extending 300 m below the paleo-seafloor. The paleo-seafloor strikes roughly east-west, dipping 30˚ to the north. At depth the fault zone occurs as an anticlinal form plunging 40˚ to the west. A second fault strikes approximately north-south, with a near vertical dip. The fault rock outcrops as reddish weathered talc + sulfide in 0.1-2 m wide anastomosing bands, with numerous splays. Talc replaces serpentinite in the fault rocks, and the talc rocks are enriched in Si, metals (Fe, Cu, Pb), Light Rare Earth Elements (LREE), have variable Eu anomalies, and have low Mg, Cr and Ni contents. In some cases gabbro dikes are associated with talc-alteration and may have enhanced fluid flow. Sulfide from a fault rock has d34S=5.7‰. The mineralogy and chemistry of the fault rocks indicate that the fault acted as the upflow pathway for high-T black-smoker type fluids. Traverses away from the fault (up to 1 km) and with depth below the seafloor (up to 500 m) reveal variable influences of hydrothermal fluids, but there are no consistent trends with distance. Background serpentinites 500 m beneath the paleoseafloor have LREE depleted trends. Other serpentinites exhibit correlations of LREE with HFSE as the result of melt percolation, but there is significant scatter, and hydrothermal effects include LREE enrichment

Cancer incidence rates and trends among children and adolescents in Piedmont, 1967-2011.

PubMed

Isaevska, Elena; Manasievska, Milena; Alessi, Daniela; Mosso, Maria Luisa; Magnani, Corrado; Sacerdote, Carlotta; Pastore, Guido; Fagioli, Franca; Merletti, Franco; Maule, Milena

2017-01-01

In the past, increases in childhood cancer incidence were reported in Europe and North America. The aim of this study is to show updated patterns of temporal behavior using data of the Childhood Cancer Registry of Piedmont (CCRP), a region with approximately 4.5 million inhabitants in North-West Italy. CCRP has been recording incident cases in children (0-14 years) since 1967 and in adolescents (15-19) since 2000. Time trends were estimated as annual percent change (APC) over the 1976-2011 period for children, and over 2000-2011 for both children and adolescents. CCRP registered 5020 incident cases from 1967 to 2011. Incidence rates were 157 per million person-years for children (1967-2011) and 282 for adolescents (2000-2011). From 1976-2011, increasing trends were observed in children for all neoplasms (APC 1.1, 95%CI: 0.8; 1.5) and for both embryonal and non-embryonal tumors: 1.1%, (0.5; 1.6) and 1.2%, (0.7; 1.6), respectively. Increases were observed in several tumor types, including leukemia, lymphoma, central nervous system tumors and neuroblastoma. In 2000-2011, incidence rates showed mostly non statistically significant variations and large variability. The observation of trends over a long period shows that the incidence of most tumors has increased, and this is only partially explained by diagnostic changes. Large rate variability hampers interpretation of trend patterns in short periods. Given that no satisfying explanation for the increases observed in the past was ever found, efforts must be made to understand and interpret this peculiar and still ununderstood pattern of childhood cancer incidence.

International trends in liver cancer incidence, overall and by histologic subtype, 1978-2007.

PubMed

Petrick, Jessica L; Braunlin, Megan; Laversanne, Mathieu; Valery, Patricia C; Bray, Freddie; McGlynn, Katherine A

2016-10-01

Primary liver cancer, the most common histologic types of which are hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC), is the second leading cause of cancer death worldwide. While rising incidence of liver cancer in low-risk areas and decreasing incidence in some high-risk areas has been reported, trends have not been thoroughly explored by country or by histologic type. We examined liver cancer incidence overall and by histology by calendar time and birth cohort for selected countries between 1978 and 2007. For each successive 5-year period, age-standardized incidence rates were calculated from volumes V-IX of the Cancer Incidence in Five Continents electronic database (CI5plus) and the newly released CI5X (volume X) database. Wide global variations persist in liver cancer incidence. Rates of liver cancer remain highest in Asian countries, specifically Eastern and South-Eastern Asian countries. While rates in most of these high-risk countries have been decreasing in recent years, rates in India and several low-risk countries of Africa, Europe, the Americas, and Oceania have been on the rise. Liver cancer rates by histologic type tend to convey a similar temporal profile. However, in Thailand, France, and Italy, ICC rates have increased while HCC rates have declined. We expect rates in high-risk countries to continue to decrease, as the population seroprevalence of hepatitis B virus (HBV) continues to decline. In low-risk countries, targeted screening and treatment of the hepatitis C virus (HCV), treatment of diabetes and primary prevention of obesity, will be key in reducing future liver cancer incidence. © 2016 UICC.

SeaWIFS Postlaunch Technical Report Series. Volume 13; The SeaWiFS Photometer Revision for Incident Surface Measurement (SeaPRISM) Field Commissioning

NASA Technical Reports Server (NTRS)

Hooker, Stanford B. (Editor); Zibordi, Giuseppe; Berthon, Jean-Francois; Bailey, Sean W.; Pietras, Christophe M.; Firestone, Elaine R. (Editor)

2000-01-01

This report documents the scientific activities that took place at the Acqua Alta Oceanographic Tower (AAOT) in the northern Adriatic Sea off the coast of Italy from 2-6 August 1999. The ultimate objective of the field campaign was to evaluate the capabilities of a new instrument called the SeaWiFS Photometer Revision for Incident Surface Measurements (SeaPRISM). SeaPRISM is based on a CE-318 sun photometer made by CIMEL Electronique (Paris, France). The CE-318 is an automated, robotic system which measures the direct sun irradiance plus the sky radiance in the sun plane and in the almucantar plane. The data are transmitted over a satellite link, and this remote operation capability has made the device very useful for atmospheric measurements. The revision to the CE-318 that makes the instrument potentially useful for SeaWiFS calibration and validation activities is to include a capability for measuring the radiance leaving the sea surface in wavelengths suitable for the determination of chlorophyll a concentration. The initial evaluation of this new capability involved above- and in-water measurement protocols. An intercomparison of the water-leaving radiances derived from SeaPRISM and an in-water system showed the overall spectral agreement was approximately 8.6%, but the blue-green channels intercompared at the 5% level. A blue-green band ratio comparison was at the 4% level.

The Influence of Vegetation and Landscape Structural Connectivity on Butterflies (Lepidoptera: Papilionoidea and Hesperiidae), Carabids (Coleoptera: Carabidae), Syrphids (Diptera: Syrphidae), and Sawflies (Hymenoptera: Symphyta) in Northern Italy Farmland.

PubMed

Burgio, Giovanni; Sommaggio, Daniele; Marini, Mario; Puppi, Giovanna; Chiarucci, Alessandro; Landi, Sara; Fabbri, Roberto; Pesarini, Fausto; Genghini, Marco; Ferrari, Roberto; Muzzi, Enrico; van Lenteren, Joop C; Masetti, Antonio

2015-10-01

Landscape structure as well as local vegetation influence biodiversity in agroecosystems. A study was performed to evaluate the effect of floristic diversity, vegetation patterns, and landscape structural connectivity on butterflies (Lepidoptera: Papilionoidea and Hesperiidae), carabids (Coleoptera: Carabidae), syrphids (Diptera: Syrphidae), and sawflies (Hymenoptera: Symphyta). Vegetation analysis and insect samplings were carried out in nine sites within an intensively farmed landscape in northern Italy. Plant species richness and the percentage of tree, shrub, and herb cover were determined by means of the phytosociological method of Braun-Blanquet. Landscape structural connectivity was measured as the total length of hedgerow network (LHN) in a radius of 500 m around the center of each sampling transect. Butterflies species richness and abundance were positively associated both to herb cover and to plant species richness, but responded negatively to tree and shrub cover. Shrub cover was strictly correlated to both species richness and activity density of carabids. The species richness of syrphids was positively influenced by herb cover and plant richness, whereas their abundance was dependent on ligneous vegetation and LHN. Rarefaction analysis revealed that sawfly sampling was not robust and no relationship could be drawn with either vegetation parameters or structural connectivity. The specific responses of each insect group to the environmental factors should be considered in order to refine and optimize landscape management interventions targeting specific conservation endpoints. © The Authors 2015. Published by Oxford University Press on behalf of Entomological Society of America. All rights reserved. For Permissions, please email: journals.permissions@oup.com.