Sample records for nuclear structure session

  1. Highlight on the dynamic organization of the nucleus.

    PubMed

    Thorpe, Stephen D; Charpentier, Myriam

    2017-01-02

    The last decade has seen rapid advances in our understanding of the proteins of the nuclear envelope, which have multiple roles including positioning the nucleus, maintaining its structural organization, and in events ranging from mitosis and meiosis to chromatin positioning and gene expression. Diverse new and stimulating results relating to nuclear organization and genome function from across kingdoms were presented in a session stream entitled "Dynamic Organization of the Nucleus" at this year's Society of Experimental Biology (SEB) meeting in Brighton, UK (July 2016). This was the first session stream run by the Nuclear Dynamics Special Interest Group, which was organized by David Evans, Katja Graumann (both Oxford Brookes University, UK) and Iris Meier (Ohio State University, USA). The session featured presentations on areas relating to nuclear organization across kingdoms including the nuclear envelope, chromatin organization, and genome function.

  2. SUNrises on the International Plant Nucleus Consortium: SEB Salzburg 2012.

    PubMed

    Graumann, Katja; Bass, Hank W; Parry, Geraint

    2013-01-01

    The nuclear periphery is a dynamic, structured environment, whose precise functions are essential for global processes-from nuclear, to cellular, to organismal. Its main components-the nuclear envelope (NE) with inner and outer nuclear membranes (INM and ONM), nuclear pore complexes (NPC), associated cytoskeletal and nucleoskeletal components as well as chromatin are conserved across eukaryotes (Fig. 1). In metazoans in particular, the structure and functions of nuclear periphery components are intensely researched partly because of their involvement in various human diseases. While far less is known about these in plants, the last few years have seen a significant increase in research activity in this area. Plant biologists are not only catching up with the animal field, but recent findings are pushing our advances in this field globally. In recognition of this developing field, the Annual Society of Experimental Biology Meeting in Salzburg kindly hosted a session co-organized by Katja Graumann and David E. Evans (Oxford Brookes University) highlighting new insights into plant nuclear envelope proteins and their interactions. This session brought together leading researchers with expertise in topics such as epigenetics, meiosis, nuclear pore structure and functions, nucleoskeleton and nuclear envelope composition. An open and friendly exchange of ideas was fundamental to the success of the meeting, which resulted in founding the International Plant Nucleus Consortium. This review highlights new developments in plant nuclear envelope research presented at the conference and their importance for the wider understanding of metazoan, yeast and plant nuclear envelope functions and properties.

  3. SUNrises on the International Plant Nucleus Consortium

    PubMed Central

    Graumann, Katja; Bass, Hank W.; Parry, Geraint

    2013-01-01

    The nuclear periphery is a dynamic, structured environment, whose precise functions are essential for global processes—from nuclear, to cellular, to organismal. Its main components—the nuclear envelope (NE) with inner and outer nuclear membranes (INM and ONM), nuclear pore complexes (NPC), associated cytoskeletal and nucleoskeletal components as well as chromatin are conserved across eukaryotes (Fig. 1). In metazoans in particular, the structure and functions of nuclear periphery components are intensely researched partly because of their involvement in various human diseases. While far less is known about these in plants, the last few years have seen a significant increase in research activity in this area. Plant biologists are not only catching up with the animal field, but recent findings are pushing our advances in this field globally. In recognition of this developing field, the Annual Society of Experimental Biology Meeting in Salzburg kindly hosted a session co-organized by Katja Graumann and David E. Evans (Oxford Brookes University) highlighting new insights into plant nuclear envelope proteins and their interactions. This session brought together leading researchers with expertise in topics such as epigenetics, meiosis, nuclear pore structure and functions, nucleoskeleton and nuclear envelope composition. An open and friendly exchange of ideas was fundamental to the success of the meeting, which resulted in founding the International Plant Nucleus Consortium. This review highlights new developments in plant nuclear envelope research presented at the conference and their importance for the wider understanding of metazoan, yeast and plant nuclear envelope functions and properties. PMID:23324458

  4. Proceedings of the 2. MIT international conference on the next generation of nuclear power technology. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1993-12-31

    The goal of the conference was to try to attract a variety of points of view from well-informed people to debate issues concerning nuclear power. Hopefully from that process a better understanding of what one should be doing will emerge. In organizing the conference lessons learned from the previous one were applied. A continuous effort was made to see to it that the arguments for the alternatives to nuclear power were given abundant time for presentation. This is ultimately because nuclear power is going to have to compete with all of the energy technologies. Thus, in discussing energy strategy allmore » of the alternatives must be considered in a reasonable fashion. The structure the conference used has seven sessions. The first six led up to the final session which was concerned with what the future nuclear power strategy should be. Each session focused upon a question concerning the future. None of these questions has a unique correct answer. Rather, topics are addressed where reasonable people can disagree. In order to state some of the important arguments for each session`s question, the combination of a keynote paper followed by a respondent was used. The respondent`s paper is not necessarily included to be a rebuttal to the keynote; but rather, it was recognized that two people will look at a complex question with different shadings. Through those two papers the intention was to get out the most important arguments affecting the question for the session. The purpose of the papers was to set the stage for about an hour of discussion. The real product of this conference was that discussion.« less

  5. Panel session on "how to meet the challenges for nuclear power".

    PubMed

    Tenforde, Thomas S

    2011-01-01

    This panel session at the 2009 Annual Meeting involved a discussion of views of government, industry, and national research laboratory members on the primary future goals in developing advanced nuclear reactor and nuclear fuel cycle designs, fuel management, and used fuel disposal options. The session at the 2009 NCRP Annual Meeting on "How to Meet the Challenges for Nuclear Power" was chaired by Mary E. Clark of the U.S. Environmental Protection Agency and focused on efforts in the United States and worldwide to expand nuclear capabilities for electric power production in a safe, secure, and environmentally acceptable manner. This paper briefly summarizes the key topics discussed in five presentations during this session of the NCRP Annual Meeting. Copyright © 2010 Health Physics Society

  6. The Energy Crisis: A New Chemistry Course for Nonscience Majors

    ERIC Educational Resources Information Center

    Piraino, Marie J.

    1974-01-01

    Describes a course structured around nuclear energy, fossil fuel energy, food energy, and the population explosion. The course uses classroom discussion and laboratory sessions to stress basic chemical principles and relevance to the student. A topical outline is included. (GS)

  7. The US Nuclear Data Network

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1993-10-19

    This report discusses the following topics: US Nuclear Data Network Meeting; TUNL A=3--20 Data Project Activity Report 1993; INEL Mass-chain Evaluation Project Activity Report for 1993; 1993 Isotopes; Nuclear Data Project Activity Report; The NNDC Activity Report Parts A and B; Minutes of the Formats and Procedures Subcommittee; Evaluation of High-spin Nuclear Data for ENSDF and Table of Superdeformed Nuclear Bands; Proposal for Support of a Experimental High-spin; Data File/Data-Network Coordinator; Radioactive Decay and Applications; A Plan for a Horizontal Evaluation of Decay Data; ENSDF On-line System; The MacNuclide Project Expanding the Scope of the Nuclear Structure Reference File; ENSDAT:more » Evaluated Nuclear Structure Drawings and Tables; Cross Section Evaluation Working Group (CSEWG) and CSEWG Strategy Session; A Draft Proposal for a USNDN Program Advisory Council; Recommendations of Focus Group 1; Recommendations of Focus Group 2; Recommendations of Focus Group 3; Recommendations of Focus Group 4; The Table of Isotopes; The Isotopes CD-ROM; Electronic Table of Isotopes (ETOI); and Electronic Access to Nuclear Data.« less

  8. Highlights lecture EANM 2014: "Gimme gimme gimme those nuclear Super Troupers".

    PubMed

    de Jong, Marion; Van Laere, Koen

    2015-04-01

    The EANM Congress 2014 took place in Gothenburg, Sweden, from 18 to 22 October under the presidency of Prof. Wim Oyen, chair of the EANM Scientific Committee. Prof. Peter Gjertsson chaired the Local Organizing Committee, according to the standardized EANM congress structure. The meeting was a highlight for the multidisciplinary community that forms the heart and soul of nuclear medicine; attendance was exceptionally high. In total almost 5,300 participants came to Gothenburg, and 1,397 colleagues participated via the EANM LIVE sessions ( http://eanmlive.eanm.org/index.php ). Participants from all continents were presented with an excellent programme consisting of symposia, scientific and featured sessions, CME sessions, and plenary lectures. These lectures were devoted to nuclear medicine therapy, hybrid imaging and molecular life sciences. Two tracks were included in the main programme, clustering multi-committee involvement: the 5th International Symposium on Targeted Radionuclide-therapy and Dosimetry (ISTARD) and the first Molecules to Man (M2M) track, an initiative of the EANM Committees for Translational Molecular Imaging, Radiopharmacy and Drug Development. The industry made a substantial contribution to the success of the congress demonstrating the latest technology and innovations in the field. During the closing Highlights Lecture, a selection of the best-rated abstracts was presented including diverse areas of nuclear medicine: physics and instrumentation, radiopharmacy, preclinical imaging, oncology (with a focus on the clinical application of newly developed tracers) and radionuclide therapy, cardiology and neurosciences. This Highlights Lecture could only be a brief summary of the large amount of data presented and discussed during the meeting, which can be found in much greater detail in the congress proceedings book, published as Volume 41, Supplement 2 of the European Journal of Nuclear Medicine and Molecular Imaging in October 2014.

  9. Proceedings of the Third NRC/ASME Symposium on Valve and Pump Testing. Session 1A--Session 2C: Volume 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1994-07-01

    The 1994 Symposium on Valve and Pump Testing, jointly sponsored by the Board of Nuclear Codes and Standards of the American Society of Mechanical Engineers and by the Nuclear Regulatory Commission, provides a forum for the discussion of current programs and methods for inservice testing and motor-operated valve testing at nuclear power plants. The symposium also provides an opportunity to discuss the need to improve that testing in order to help ensure the reliable performance of pumps and valves. The participation of industry representatives, regulators, and consultants results in the discussion of a broad spectrum of ideas and perspectives regardingmore » the improvement of inservice testing of pumps and valves at nuclear power plants. This document, Volume 1, covers sessions 1A through session 2C. The individual papers have been cataloged separately.« less

  10. Proceedings of the Symposium on Training of Nuclear Facility Personnel (7th, Orlando, Florida, April 27-30, 1987).

    ERIC Educational Resources Information Center

    Oak Ridge National Lab., TN.

    These proceedings contain program highlights as well as 45 papers given during six sessions of the Symposium on Training of Nuclear Facility Personnel. The six sessions are entitled: (1) the training challenge; (2) influences on nuclear training; (3) the human factors--training partnership and factors affecting job performance; (4) current…

  11. PREFACE: International Nuclear Physics Conference 2010 (INPC2010)

    NASA Astrophysics Data System (ADS)

    Dilling, Jens

    2011-09-01

    The International Nuclear Physics Conference 2010 (INPC 2010) was held from 4-9 July in Vancouver, Canada, hosted by TRIUMF, the Canadian National Laboratory for Particle and Nuclear Physics. The INPC is the main conference in the field of nuclear physics, endorsed and supported by IUPAP (International Union for Pure and Applied Physics) and held every three years. This year's conference was the 25th in the series and attracted over 750 delegates (150 graduate students) from 43 countries. The conference's hallmark is its breadth in nuclear physics; topics included structure, reactions, astrophysics, hadronic structure, hadrons in nuclei, hot and dense QCD, new accelerators and underground nuclear physics facilities, neutrinos and nuclei, and applications and interdisciplinary research. The conference started with a public lecture 'An Atom from Vancouver' by L Krauss (Arizona), who gave a broad perspective on how nuclear physics is key to a deeper understanding of how the Universe was formed and the birth, life, and death of stars. The conference opened its scientific plenary program with a talk by P Braun-Munzinger (GSI/EMMI Darmstadt) who highlighted the progress that has been made since the last conference in Tokyo 2007. The presentation showcased theoretical and experimental examples from around the world. All topics were well represented by plenary sessions and well attended afternoon parallel sessions where over 250 invited and contributed talks were presented, in addition to over 380 poster presentations. The poster sessions were among the liveliest, with high participation and animated discussions from graduate students and post-doctoral fellows. Many opportunities were found to connect to fellow nuclear physicists across the globe and, particularly for conferences like the INPC which span an entire field, many unexpected links exist, often leading to new discussions or collaborations. Among the scientific highlights were the presentations in the fields of Hot and Dense QCD reporting on experimental and theoretical progress at the RHIC facility. The Nuclear Reactions session provided highlights from the many new and exciting facilities including the RIKEN RIBF in Japan, and an outlook of what we can expect from FAIR (Germany) and FRIB (USA). The quest towards the 'Island of Stability' for the Superheavy Element community is still on, and new progress was reported with the identification of element 114. Impressive progress in the theoretical sector, in particular with ab-initio approaches, was presented as well. Applications of these methods and progress in the nucleon-nucleon interactions were presented in the Nuclear Structure session, where 3-body forces interactions are now considered state of the art. Predictions of such calculations can then be tested by experiments, as presented, for example, for ground state properties of exotic nuclei with laser experiments and ion trap measurements. In-beam or in-flight experiments pave the way to even more exotic isotopes where new magic numbers for the nuclear shell model are appearing. This will also prove relevant for Nuclear Astrophysics, where significant progress was achieved experimentally with new direct capture reaction measurements with rare beams and background suppressed facilities located in underground laboratories. Neutron star research and new modeling results of core-collapse supernovae were presented, which clearly indicated the need for neutrino interactions. Neutrinos also played a large role in other sessions such as the New Facilities and Instrumentation session where, among other new exciting projects, the deep underground facilities were presented. The first beam results from long-baseline oscillation experiments showed progress in this field, and double-beta decay experiments are nearing their first possible results, something that the community of nuclear physicists, but also others, are keenly waiting for. The Standard Model Tests and Fundamental Symmetries session is always one of the conference highlights. There, progress on Standard Model tests employing atomic nuclei or nuclear physics methods - which are used to probe complimentary sectors to large particle physics experiments, for example atomic and neutron EDM experiments - is reported. Recent progress was reported in the sector of nuclear beta decay as related to the testing of the CKM unitarity matrix, as well as the W-mass and the Weak Mixing Angle. The muon anomalous magnetic moment and its sensitivity for probing new physics and future experimental improvements are anticipated and showcase the activity in the field. The large oral and poster presentation program was extended to include special presentations by the IUPAP young scientist award winners. This prize is given out in the field of nuclear physics every three years during the INPC conference, and this year's winners were: Kenji Fukushima (Yukawa Institute for Theoretical Physics, Kyoto University), Peter Mueller (Argonne National Laboratory), and Lijuan Ruan (Brookhaven National Laboratory). These three scientists represent future excellence in nuclear physics in the fields of theoretical QCD, experimental techniques related to quark gluon plasma, and precision experiments in low energy nuclear halo physics. One keenly anticipated presentation, 'The Lamb shift in muonic hydrogen experiment', presented the results of the measurement of the proton rms charge radius. These results claimed a 5 sigma deviation from the established CODATA-value and in the future more tests will be needed to verify these findings. INPC 2010 made a special effort to attract many graduate students and post-doctoral fellows to the conference. This was achieved by a number of efforts, for example, TRIUMF combined its traditional summer school with the US National Science Foundation summer school for nuclear physics, and offered the school directly prior to the conference. This allowed the school to recruit some of the INPC delegates as lecturers, but also gave a broad overview of the field of nuclear physics before the conference. In addition INPC 2010 teamed up with the publishing house of Nuclear Physics A to provide awards to the best student oral presentation and the three top poster presentations at the conference. An international panel of judges together with members from the editorial board of Nuclear Physics A finally decided on the following award winners among a very strong field of applicants: P Finlay (Guelph, Canada), oral presentation; Y J Kim (Indiana, USA), E Rand (Guelph, Canada), and T Brunner (Munich, Germany) for posters. A treat of a different kind was in store for delegates at the conference banquet at the Museum of Anthropology. Olivia Fermi, the granddaughter of nuclear physics 'royalty' Enrico Fermi, was among the guests and shared in the after-dinner speech some anecdotes from her life growing up in the Fermi household. This, together with the unique setting of the museum of First Nations' artefacts and art pieces and overlooking the Pacific Ocean and the skyline of Vancouver, was a perfect fit for a very special conference. The field of nuclear physics clearly presented itself in a healthy and dynamic state, with many young people eagerly anticipating the advent of new experiments, theory, and facilities. At the end of the conference IUPAP announced the selection of the host of the next INPC conference: it will be held in 2013 in Florence, Italy. On behalf of the Local Organizing Committee we would like to acknowledge the great work of the Program Committee and the Session Chairs, who were responsible for the excellent selection and execution of the Parallel Session Program, the International Advisory Program and the work for the Plenary Session selections, and the judges for the Student Awards. Moreover, we would like to acknowledge the support of TRIUMF as the host and main organizer of the conference. Additional support was provided by the Canadian Institute for Nuclear Physics and the International Union for Pure and Applied Physics (IUPAP). Very grateful acknowledgments go to the many volunteers and student helpers who ensured the frictionless and seamless execution of a very fruitful and exciting conference. We wish the organizers of the next INPC in Florence the best of luck and we hope to see you there. On behalf of the Local Organizing Committee Jens Dilling (Chair of INPC 2010)

  12. Scientific session of the General meeting of the Physical Sciences Division of the Russian Academy of Sciences (7 December 2015)

    NASA Astrophysics Data System (ADS)

    2016-05-01

    A scientific session of the General meeting of the Physical Sciences Division of the Russian Academy of Sciences (RAS) was held in the conference hall of the Lebedev Physical Institute, RAS on 7 December 2015. The papers collected in this issue were written based on talks given at the session (the program of the session is available on the RAS Physical Sciences Division website http://www.gpad.ac.ru). (1) Loshchenov V B (Prokhorov General Physics Institute, RAS, Moscow) "Pharmacodynamics of a nanophotosensitizer under irradiation by an electromagnetic field: from THz to Cherenkov radiation"; (2) Zhuikov B L (Institute for Nuclear Research, RAS, Moscow) "Successes and problems in the development of medical radioisotope production in Russia"; (3) Tikhonov Yu A (Budker Institute of Nuclear Physics, SB RAS, Novosibirsk) "Applying nuclear physics methods in healthcare"; (4) Turchin I V (Institute of Applied Physics, RAS, Nizhny Novgorod) "Methods of biomedical optical imaging: from subcellular structures to tissues and organs"; (5) Breus T K, Petrukovich A A (Space Research Institute, RAS, Moscow), Binhi V N (Prokhorov General Physics Institute, RAS, Moscow; Lomonosov Moscow State University, Moscow) "Magnetic factor in solar-terrestrial relations and its impact on the human body: physical problems and prospects for research"; (6) Makarov D I (Special Astrophysical Observatory, RAS, Nizhnii Arkhyz, Zelenchukskii region, Karachai-Cherkessian Republic) "Studying the Local University". Papers based on oral reports 2, 4, and 5 are presented below. • Successes and problems in the development of medical radioisotope production in Russia, B L Zhuikov Physics-Uspekhi, 2016, Volume 59, Number 5, Pages 481-486 • Methods of biomedical optical imaging: from subcellular structures to tissues and organs, I V Turchin Physics-Uspekhi, 2016, Volume 59, Number 5, Pages 487-501 • Magnetic factor in solar-terrestrial relations and its impact on the human body: physical problems and prospects for research, T K Breus, V N Binhi, A A Petrukovich Physics-Uspekhi, 2016, Volume 59, Number 5, Pages 502-510

  13. SINGER: A Computer Code for General Analysis of Two-Dimensional Reinforced Concrete Structures. Volume 1. Solution Process

    DTIC Science & Technology

    1975-05-01

    Conference on Earthquake Engineering, Santiago de Chile, 13-18 January 1969, Vol. I , Session B2, Chilean Association oil Seismology and Earth- quake...Nuclear Agency May 1975 DISTRIBUTED BY: KJ National Technical Information Service U. S. DEPARTMENT OF COMMERCE ^804J AFWL-TR-74-228, Vol. I ...CM o / i ’•fu.r ) V V AFWL-TR- 74-228 Vol. I SINGER: A COMPUTER CODE FOR GENERAL ANALYSIS OF TWO-DIMENSIONAL CONCRETE STRUCTURES Volum« I

  14. QCD and Multiparticle Production - Proceedings of the XXIX International Symposium on Multiparticle Dynamics

    NASA Astrophysics Data System (ADS)

    Sarcevic, Ina; Tan, Chung-I.

    2000-07-01

    The Table of Contents for the full book PDF is as follows: * Preface * Monday morning session: Hadronic Final States - Conveners: E. de Wolf and J. W. Gary * Session Chairman: J. W. Gary * Inclusive Jets at the Tevatron * Forward Jets, Dijets, and Subjets at the Tevatron * Inclusive Hadron Production and Dijets at HERA * Recent Opal Results on Photon Structure and Interactions * Review of Two-Photon Physics at LEP * Session Chairman: E. de Wolf * An Intriguing Area-Law-Based Hadron Production Scheme in e+e- Annihilation and Its Possible Extensions * Hyperfine Splitting in Hadron Production at High Energies * Event Selection Effects on Multiplicities in Quark and Gluon Jets * Quark and Gluon Jet Properties at LEP * Rapidity Gaps in Quark and Gluon Jets -- A Perturbative Approach * Monday afternoon session: Diffractive and Small-x - Conveners: M. Derrick and A. White * Session Chairman: A. White * Structure Functions: Low x, High y, Low Q2 * The Next-to-Leading Dynamics of the BFKL Pomeron * Renormalization Group Improved BFKL Equation * Session Chairman: G. Briskin * New Experimental Results on Diffraction at HERA * Diffractive Parton Distributions in Light-Cone QCD * The Logarithmic Derivative of the F2 Structure Function and Saturation * Spin Dependence of Diffractive DIS * Monday evening session * Session Chairman: M. Braun * Tests of QCD with Particle Production at HERA: Review and Outlook * Double Parton Scattering and Hadron Structure in Transverse Space * The High Density Parton Dynamics from Eikonal and Dipole Pictures * Hints of Higher Twist Effects in the Slope of the Proton Structure Function * Tuesday morning session: Correlations and Fluctuations - Conveners: R. Hwa and M. Tannenbaum * Session Chairman: A. Giovannini -- Fluctuations and Correlations * Bose-Einstein Results from L3 * Short-Range and Long-Range Correlations in DIS at HERA * Coior Mutation Model, Intermittency, and Erraticity * QCD Queuing and Hadron Multiplicity * Soft and Semi-hard Components in Multiplicity Distributions in the TeV Region * Qualitative Difference Between Particle Production Dynamics in Soft and Hard Processes * Session Chairman: M. Tannenbaum -- Bose-Einstein Correlations * Questions in Bose-Einstein Correlations * The Source Size Dependence on the mhadron Applying Fermi and Bose Statistics and I-Spin Invariance * Signal of Partial UA(1) Symmetry Restoration from Two-Pion Bose-Einstein Correlations * Multiparticle Bose-Einstein Correlations in Heavy-Ion Collisions * Tuesday afternoon session: Heavy Ion Collisions - Conveners: B. Müller and J. Statchel * Session Chairman: J. Stachel * Probing Baryon Freeze-out Density at the AGS with Proton Correlations * Centrality Dependence of Hadronic Observables at CERN SPS * Study of Transverse Momentum Spectra in pp Collisions with a Statistical Model of Hadronisation * Session Chairman: B. Brower * Production of Light (Anti-)Nuclei with E864 at the AGS * QCD Critical Point in Heavy-Ion Collision Experiments * Tuesday evening session * Session Chairman: H. M. Fried * Oscillating Hq, Event Shapes, and QCD * Critical Behavior of Quark-Hadron Phase Transition * Shadowing of Gluons at RHIC and LHC * Parton Distributions in Nuclei at Small x * Wednesday morning session: Diffraction and Small x - Conveners: M. Derrick and A. White * Session Chairman: C. Pajares * High-Energy Effective Action from Scattering of Shock Waves in QCD * The Triangle Anomaly in the Triple-Regge Limit * CDF Results on Hard Diffraction and Rapidity Gap Physics * DØ Results on Hard Diffraction * Interjet Rapidity Gaps in Perturbative QCD * Pomeron: Beyond the Standard Approach * Factorization and Diffractive Production at Collider Energies * Thursday morning session: Heavy Ion Collisions - Conveners: B. Müller and J. B. Stachel * Session Chairman: N. Schmitz * Summary of J/ψ Suppression Data and Preliminary Results on Multiplicity Distributions in PB-PB Collisions from the NA50 Experiment * Duality and Chiral Restoration from Dilepton Production in Relativistic Heavy-Ion Collisions * Session Chairman: I. Sarcevic * Transport-Theoretical Analysis of Reaction Dynamics, Particle Production and Freeze-out at RHIC * Inclusive Particle Spectra and Exotic Particle Searches Using STAR * The First Fermi in a High Energy Nuclear Collision * Probing the Space-Time Evolution of Heavy Ion Collisions with Bremsstrahlung * Thursday afternoon session: Hadronic Final States - Conveners: E. de Wolf and J. Gary * Session Chairman: F. Verbeure * QCD with SLD * QCD at LEP II * Multidimensional Analysis of the Bose-Einstein Correlations at DELPHI * Study of Color Singlet with Gluonic Subsinglet by Color Effective Hamiltonian * Correlations and Fluctuations - Conveners: R. Hwa and M. Tannenbaum * Session Chairman: R. C. Hwa -- Fluctuations in Heavy-Ion Collisions * Scale-Local Statistical Measures and the Multiparticle Final State * Centrality and ET Fluctuations from p + Be to Au + Au at AGS Energies * Order Parameter of Single Event * Multiplicities, Transverse Momenta and Their Correlations from Percolating Colour Strings * Probing the QCD Critical Point in Nuclear Collisions * Event-by-Event Fluctuations in Pb + Pb Collisions at the CERN SPS * Friday morning session: High Energy Collisions and Cosmic-Ray/Astrophysics - Conveners: F. Halzen and T. Stanev * Session Chairman: U. Sukhatme * Rethinking the Eikonal Approximation * QCD and Total Cross-Sections * The Role of Multiple Parton Collisions in Hadron Collisions * Effective Cross Sections and Spatial Structure of the Hadrons * Looking for the Odderon * QCD in Embedded Coordinates * Session Chairman: F. Bopp * Extensive Air Sbowers and Hadronic Interaction Models * Penetration of the Earth by Ultrahigh Energy Neutrinos and the Parton Distributions Inside the Nucleon * Comparison of Prompt Muon Observations to Charm Expectations * Friday afternoon session: Recent Developments - Conveners: R. Brower and I. Sarcevic * Session Chairman: G. Guralnik * The Relation Between Gauge Theories and Gravity * From Black Holes to Pomeron: Tensor Glueball and Pomeron Intercept at Strong Coupling * Summary Talks * Summary of Results of the Ultrarelativistic Heavy Ion Fixed Target Program * Review of Theory Talks * Summary of Experimental Talks * List of Participants

  15. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vogt, J R

    A total of 75 papers were presented on nuclear methods for analysis of environmental and biological samples. Sessions were devoted to software and mathematical methods; nuclear methods in atmospheric and water research; nuclear and atomic methodology; nuclear methods in biology and medicine; and nuclear methods in energy research.

  16. 78 FR 4393 - Sunshine Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-01-22

    ... DEFENSE NUCLEAR FACILITIES SAFETY BOARD Sunshine Act Notice AGENCY: Defense Nuclear Facilities... given of the Defense Nuclear Facilities Safety Board's (Board) public meeting and hearing described... Session II, the Board will receive testimony concerning safety at Pantex defense nuclear facilities. The...

  17. PREFACE: 3rd International Workshop on "State of the Art in Nuclear Cluster Physics"

    NASA Astrophysics Data System (ADS)

    Yamada, Taiichi; Kanada-En'yo, Yoshiko

    2014-12-01

    The 3rd International Workshop on "State of the Art in Nuclear Cluster Physics"(SOTANCP3) was held at KGU Kannai Media Center, Kanto Gakuin University, Yokohama, Japan, from May 26 to 30, 2014. Yokohama is the second largest city in Japan, about 25 km southeast of Tokyo. The first workshop of the series was held in Strasbourg, France, in 2008 and the second one was in Brussels, Belgium, in 2010. The purpose of SOTANCP3 was to discuss the present status and future perspectives of the nuclear cluster physics. The following nine topics were selected in order to cover most of the scientific programme and highlight an area where new ideas have emerged over recent years: (1) Cluster structures and many-body correlations in stable and unstable nuclei (2) Clustering aspects of nuclear reactions and resonances (3) Alpha condensates and analogy with condensed matter approaches (4) Role of tensor force in cluster physics and ab initio approaches (5) Clustering in hypernuclei (6) Nuclear fission, superheavy nuclei, and cluster decay (7) Cluster physics and nuclear astrophysics (8) Clustering in nuclear matter and neutron stars (9) Clustering in hadron and atomic physics There were 122 participants, including 53 from 17 foreign countries. In addition to invited talks, we had many talks selected from contributed papers. There were plenary, parallel, and poster sessions. Poster contributions were also presented as four-minute talks in parallel sessions. This proceedings contains the papers presented in invited and selected talks together with those presented in poster sessions. We would like to express our gratitude to the members of the International Advisory Committee and those of the Organizing Committee for their efforts which made this workshop successful. In particular we would like to present our great thanks to Drs. Y. Funaki, W. Horiuchi, N. Itagaki, M. Kimura, T. Myo, and T. Yoshida. We would like also to thank the following organizations for their sponsors: RCNP (Research Center for Nuclear Physics, Osaka University), CNS (Center for Nuclear Study, University of Tokyo), JICFuS (Joint Institute for Computational Fundamental Science), and RIKEN (Nishina Center for Accelerator-Based Science, Institute of Physical and Chemical Research). This workshop was supported by Yokohama Convention & Visitors Bureau and Kanto Gakuin University. It remains to be announced that the next, the fourth in this series of SOTANCP workshops, SOTANCP4, will be held in Galveston, Texas, USA, in 2018.

  18. 3rd Miami international conference on alternative energy sources

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nejat Veziroglu, T.

    1980-01-01

    The conference includes sessions on solar energy, ocean thermal energy, wind energy, hydro power, nuclear breeders and nuclear fusion, synthetic fuels from coal or wastes, hydrogen production and uses, formulation of workable policies on energy use and energy conservation, heat and energy storage, and energy education. The volume of the proceedings presents the papers and lectures in condensed format grouped by subject under forty-two sessions for 319 presentations.

  19. 77 FR 18271 - Notice of Sunshine Act Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-27

    .... Affirmation Session (Public Meeting) (Tentative) a. FirstEnergy Nuclear Operating Co. (Davis-Besse Nuclear... NUCLEAR REGULATORY COMMISSION [NRC-2012-0002] Notice of Sunshine Act Meeting DATE: Weeks of March....m. Briefing on the Final Report of the Blue Ribbon Commission on America's Nuclear Future (Public...

  20. Building on the past, planning for the future

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Woodall, D.M.

    1996-12-31

    A University Working Conference (UWC) sponsored by the American Nuclear Society (ANS) was held on June 14 and 15, 1996, prior to the ANS Annual Meeting in Reno, Nevada. With a theme of {open_quotes}Building on the Past, Planning for the Future,{close_quotes} the meeting was the successor to the first UWC held in Philadelphia, Pennsylvania, in 1995. This workshop refined the recommendations to the national nuclear engineering academic community of the earlier UWC on strategies for success in the 21st century. This UWC had 40 attendees from academe and industry, and the program was developed around the outcomes of the Philadelphiamore » meeting. The general chair of UWC96 was Don Miller of Ohio State University, while the author of this paper served as the technical program chair. Assistant technical program chairs included Madeline Feltus of Pennsylvania State University, Dan Bullen of Iowa State University, and Gilbert Brown of the University of Massachusetts Lowell. A working conference is often loosely structured, with an informal, flexible program, consisting of a few highlight or keynote presentations followed by workshop sessions devoted to a theme area. The workshop sessions at this meeting included the following: 1. strategic planning in today`s climate; 2. university/industry research collaboration; 3. profiles of nuclear engineering and radiological engineering students, now and in the future; 4. accreditation issues, especially ABET`s engineering 2000; 5. employment of nuclear and radiological engineers; 6. new program thrusts in nuclear engineering departments; 7. uses of new technology in the classroom and laboratory; 8. internet access to information for education; 9. distance education/remote delivery of curricula.« less

  1. PREFACE: XXXIII Symposium on Nuclear Physics

    NASA Astrophysics Data System (ADS)

    Barrón-Palos, Libertad; Bijker, Roelof; Fossion, Ruben; Lizcano, David

    2010-04-01

    The attached PDF gives a full listing of contributors and organisation members. In the present volume of Journal of Physics: Conference Series we publish the proceedings of the "XXXIII Symposium on Nuclear Physics", that was held from January 5-8, 2010 at the Hacienda Cocoyoc, Morelos, Mexico. The proceedings contain the plenary talks that were presented during the conference. The abstracts of all contributions, plenary talks and posters, were published in the Conference Handbook. The Symposium on Nuclear Physics has a long and distinguished history. From the beginning it was intended to be a relatively small meeting designed to bring together some of the leading nuclear scientists in the field. Its most distinctive feature is to provide a forum for specialists in different areas of nuclear physics, both theorists and experimentalists, students, postdocs and senior scientists, in a relaxed and informal environment providing them with a unique opportunity to exchange ideas. After the first meeting in Oaxtepec in 1978, the Symposium was organized every year without interruption which makes the present one the 33rd in a row. This year's meeting was dedicated to the memory of Marcos Moshinsky, who passed away on April 1, 2009. Dr. Moshinsky was the most distinguished pioneer and promoter of nuclear physics in Mexico and Latin America and holds the record of 31 (out of 32) participations at the Symposium. In the inaugural session, Alejandro Frank (ICN-UNAM), Peter Hess (ICN-UNAM) and Jorge Flores (IF-UNAM) spoke in his honor and recalled the virtues that characterized him as a teacher, scientist, founder of schools and academic institutions, colleague and friend. His generosity, excellence and honesty were emphasized as the personal qualities that characterized both his personal and academic life. moshinksky_photo "Marcos Moshinsky (1921-2009)" The scientific program consisted of 26 invited talks and 20 posters on a wide variety of hot topics in contemporary nuclear physics, ranging from the traditional fields of nuclear structure and reactions to radioactive beams, nuclear astrophysics, hadronic physics, fundamental symmetries, ultrarelativistic heavy ions, cosmic rays and quantum chaos. The high quality of the talks, the prestige of the speakers and the broad spectrum of subjects covered in the meeting, shows that nuclear physics is a very active area at the frontier of scientific research which establishes bridges between many different disciplines. One of the exciting new areas in nuclear physics is that of radioactive beams. It provides a powerful tool not only to study exotic nuclei close to the proton and neutron drip lines to obtain important information about the nature of the nucleon-nucleon interaction in stable and unstable nuclei, but also to address questions of fundamental importance in nuclear astrophysics as well as in various applications like mass spectroscopy, the production of radioactive isotopes and medical applications (Galindo-Uribarri). There was a presentation on the FRIB project which is currently under construction in the USA and its relevance for nuclear astrophysics and the limits of stability (Sherrill and Schatz) In the session on nuclear structure, there were several talks on the nucleon-nucleon interaction in nuclei close to the proton and neutron drip lines, like neutron-proton pairing in nuclei with an equal number of protons and neutrons (Pittel), and studies of stable and unstable neutron-rich nuclei near the closed shells N = 82 and N = 50 using (d, p) transfer reactions and Coulomb excitation by means of radioactive beams (Cizewski and Padilla-Rodal). There were several talks on the importance of reaction rates for the excitation of spin-isospin resonances (Sakai), massive star evolution (Klapp) and nuclear synthesis and stellar evolution (Rolfs). In another presentation, the importance of rare isotopes for astrophysical processes was highlighted (Schatz). In addition, there were discussions about the importance of the Pauli exclusion principle and phase transitions in nuclear cluster models (Cseh and Hess) and an analysis of elastic scattering close to the Coulomb barrier in the framework of the optical model (Gómez-Camacho). Another important area is that of hadronic physics, the study of nucleons as composite systems of strongly interacting quarks and gluons. This field is situated on the borderline between nuclear and particle physics and presents a formidable challenge since the scale of the energies involved prohibits the use of the methods of perturbative QCD. In the session on hadronic physics, there were talks on chiral symmetry in non-perturbative QCD (Bietenholz), the structure of the nucleon in an unquenched quark model (Bijker), quark and meson degrees of freedom in Deeply Virtual Compton Scattering (Szczepaniak) and studies of hadronic structure by means of neutrino-induced pion production (Mariano). At ultrarelativistic energies, one can study the phase transition between hadronic matter and a new state of nuclear matter, the quark-gluon plasma. The Organizing Committee is proud to mention that the Cocoyoc 2010 meeting was one of first international conferences where the first scientific resuls from LHC were presented by the ALICE collaboration on proton-proton collisions at an energy of 900 GeV (Paic). In the session on cosmic rays, there was a talk on the origin of ultra high-energy cosmic rays (100 EeV = 1020 eV) as observed by the Pierre Auger Observatory (Medina-Tanco). Furthermore, there was a presentation of the project NuMoon which proposes to use the Moon's surface to detect cosmic rays that are out of the range of the Auger Observatory (Scholten). In addition, there was a review of the advances of the Mexican project HAWC, an observatory under construction in the Sierra Negra of Puebla (Sandoval) to study some of the most violentphenomena in the Universe through the detection of gamma rays with energies between hundreds of GeV and hundreds of TeV. At the other extreme of the energy scale is the field of the study of fundamental symmetries with novel experiments with ultra-cold neutrons. In this session, there were proposals by the NPDGamma collaboration (Gillis) and the abBA collaboration (Barr´on-Palos) to use polarized neutrons to study the weak hadronic interaction and neutron beta-decay, respectively. In another talk, there was a discussion on the measurement of the electric dipole moment of the neutron which is of fundamental importance to the standard model (Crawford). Finally, there was a session dedicated to quantum chaos where various proposals were discussed to identify chaotic behaviour in quantum systems, such as spectral fluctuations, time series and 1/f noise (Molina). Applications were presented to many-body systems in nuclear physics (Stránský) and the dripping-laser system as a quantum realization of the dripping faucet, one of the paradigms of classical chaos (Fossion). Many of the participants spent the free afternoon in the "magic village" of Tepoztlán to visit the arts and crafts market, the church, the convent or just to enjoy the good food. The most daring persons climbed the nearby cliff Tepozteco and the pyramid built on top of it to contemplate the spectacular view over the valley. As always, some of the participants of the conference prolonged their stay in Mexico to establish, to develop or to consolidate their collaborations with the local nuclear physics community. At the annual reunion of the Nuclear Physics Division which was held during the meeting, there was a long discussion on the future of the Symposium and, more generally, of the field of nuclear physics in Mexico and Latin America. Libertad Barr´on Palos, Roelof Bijker, Ruben Fossion and David Lizcano were re-elected as members of the Local Organizing Committee of the next Symposium which will be held at the Hacienda Cocoyoc from January 4-7, 2011, but now with Libertad as Chair. Libertad Barrón-Palos Roelof Bijker Ruben Fossion David Lizcano conference photo_photo

  2. NNSA Administrator Addresses the Next Generation of Nuclear Security Professionals: Part 2

    ScienceCinema

    Thomas D'Agostino

    2017-12-09

    Administrator Thomas DAgostino of the National Nuclear Security Administration addressed the next generation of nuclear security professionals during the opening session of todays 2009 Department of Energy (DOE) Computational Science Graduate Fellowship Annual Conference. Administrator DAgostino discussed NNSAs role in implementing President Obamas nuclear security agenda and encouraged the computing science fellows to consider careers in nuclear security.

  3. NNSA Administrator Addresses the Next Generation of Nuclear Security Professionals: Part 1

    ScienceCinema

    Thomas D'Agostino

    2017-12-09

    Administrator Thomas DAgostino of the National Nuclear Security Administration addressed the next generation of nuclear security professionals during the opening session of todays 2009 Department of Energy (DOE) Computational Science Graduate Fellowship Annual Conference. Administrator DAgostino discussed NNSAs role in implementing President Obamas nuclear security agenda and encouraged the computing science fellows to consider careers in nuclear security.

  4. The Impact of Declining Navy Budgets on United States Shipyards

    DTIC Science & Technology

    1992-12-01

    and the Department of Energy Defense Nuclear Facilities Panel in April 1991 that the nuclear industrial base is being crippled with the reduction in...Seapower and Strategic and Critical Materials Subcommittee and Department of Energy Defense Nuclear Facilities Panel, 102 Congress, 1st Session, Government

  5. High-intensity interval training using whole-body exercises: training recommendations and methodological overview.

    PubMed

    Machado, Alexandre F; Baker, Julien S; Figueira Junior, Aylton J; Bocalini, Danilo S

    2017-05-04

    HIIT whole body (HWB)-based exercise is a new calisthenics exercise programme approach that can be considered an effective and safe method to improve physical fitness and body composition. HWB is a method that can be applied to different populations and ages. The purpose of this study was to describe possible methodologies for performing physical training based on whole-body exercise in healthy subjects. The HWB sessions consist of a repeated stimulus based on high-intensity exercise that also include monitoring time to effort, time to recuperation and session time. The exercise intensity is related to the maximal number of movements possible in a given time; therefore, the exercise sessions can be characterized as maximal. The intensity can be recorded using ratings of perceived exertion. Weekly training frequency and exercise selection should be structured according to individual subject functional fitness. Using this simple method, there is potential for greater adherence to physical activity which can promote health benefits to all members of society. © 2017 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  6. Implementation of a Flipped Classroom for Nuclear Medicine Physician CME.

    PubMed

    Komarraju, Aparna; Bartel, Twyla B; Dickinson, Lisa A; Grant, Frederick D; Yarbrough, Tracy L

    2018-06-21

    Increasingly, emerging technologies are expanding instructional possibilities, with new methods being adopted to improve knowledge acquisition and retention. Within medical education, many new techniques have been employed in the undergraduate setting, with less utilization thus far in the continuing medical education (CME) sphere. This paper discusses the use of a new method for CME-the "flipped classroom," widely used in undergraduate medical education. This method engages learners by providing content before the live ("in class") session that aids in preparation and fosters in-class engagement. A flipped classroom method was employed using an online image-rich case-based module and quiz prior to a live CME session at a national nuclear medicine meeting. The preparatory material provided a springboard for in-depth discussion at the live session-a case-based activity utilizing audience response technology. Study participants completed a survey regarding their initial experience with this new instructional method. In addition, focus group interviews were conducted with session attendees who had or had not completed the presession material; transcripts were qualitatively analyzed. Quantitative survey data (completed by two-thirds of the session attendees) suggested that the flipped method was highly valuable and met attendee educational objectives. Analysis of focus group data yielded six themes broadly related to two categories-benefits of the flipped method for CME and programmatic considerations for successfully implementing the flipped method in CME. Data from this study have proven encouraging and support further investigations around the incorporation of this innovative teaching method into CME for nuclear imaging specialists.

  7. Proceedings of condensed papers on alternate energy sources

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Veziroglu, T.N.

    1979-01-01

    The conference covers the results of research and developments which have taken place during the last 2 years. It includes sessions on solar energy, ocean thermal energy, wind energy, hydro power, nuclear breeders and nuclear fusion, synthetic fuels from coal or waste, hydrogen production and uses. The volume of the Proceedings presents the papers and lectures in condensed format grouped by their subjects under 40 technical sessions. Condensed papers are presented for the 336 presentations; abstracts have previously appeared in the DOE Energy Data Base for 33 of the full-length papers.

  8. 10 CFR Appendix R to Part 50 - Fire Protection Program for Nuclear Power Facilities Operating Prior to January 1, 1979

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... could occur in a nuclear power plant. These sessions shall provide brigade members with experience in... A. Fire protection program. A fire protection program shall be established at each nuclear power... fires that could occur in the plant and in using the types of equipment available in the nuclear power...

  9. From a CEU '98er: 9 years and 5 research projects later

    NASA Astrophysics Data System (ADS)

    Aidala, Christine

    2007-10-01

    Since my first research experience in 1996 working in low-energy nuclear structure, the results of which were presented at the original DNP CEU poster session in Santa Fe in 1998, subsequent projects led me to weave my way through various energies and collision systems in nuclear and particle physics. Through the course of the broad exposure to research that I have been fortunate enough to experience, I have found a niche for myself in the study of nucleon spin structure. I originally got involved in the field in 1998-99 through my undergraduate senior project on studies for polarizing the proton beam at HERA in Hamburg, Germany. After a foray into particle physics followed by an unanticipated diversion from research, teaching music and English abroad, fate--and some kind individuals--would give me the opportunity to return both to physics and specifically to nucleon structure in 2001 as part of the PHENIX experiment at the Relativistic Heavy Ion Collider. Six years into my research on proton spin structure as a member of the PHENIX Collaboration, I will discuss where I am today and the non-linear path that brought me here.

  10. 77 FR 42484 - Civil Nuclear Trade Advisory Committee (CINTAC) Public Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-19

    ... a.m. Eastern Daylight Time (EDT). The public session is from 3:00 p.m.- 4:00 p.m. ADDRESSES: The..., 2012 CINTAC meeting is as follows: Closed Session (9:00 a.m.-3:00 p.m.) 1. Discussion of matters... found in 5 U.S.C. App. (10)(a)(1) and 10(a)(3). Public Session (3:00 p.m.-4:00 p.m.) 1. International...

  11. UK nuclear medicine survey, 1992-93.

    PubMed

    Elliott, A T; Elliott, F M; Shields, R A

    1996-01-01

    A postal survey of UK nuclear medicine departments was undertaken to collate information on equipment, numbers of procedures and staffing levels for the years 1992 and 1993. It was estimated that there are 235 sites undertaking nuclear medicine, the total number of procedures performed being some 490,000 in 1993 compared with 430,000 in 1989. Informal investigation suggests that the increase is due to greater usage of myocardial perfusion and lung ventilation/perfusion studies. Wide variations were noted in staffing levels, with only 22% of departments having medical cover of half-time equivalent or better: over 30% of departments have less than one consultant session per week. Approximately 20% of departments claimed to have no physics input, with a further 20% having less than one session per week.

  12. Proceedings of the 7th International Meeting on Nuclear Reactor Thermal-Hydraulics NURETH-7. Sessions 17-24

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Block, R.C.; Feiner, F.

    1995-09-01

    Technical papers accepted for presentation at the Seventh International Topical Meeting on Nuclear Reactor Thermal-Hydraulics are included in the present Proceedings. Except for the invited papers in the plenary session, all other papers are contributed papers. The topics of the meeting encompass all major areas of nuclear thermal-hydraulics, including analytical and experimental works on the fundamental mechanisms of fluid flow and heat transfer, the development of advanced mathematical and numerical methods, and the application of advancements in the field in the development of novel reactor concepts. Because of the complex nature of nuclear reactors and power plants, several papers dealmore » with the combined issues of thermal-hydraulics and reactor/power-plant safety, core neutronics and/or radiation. The participation in the conference by the authors from several countries and four continents makes the Proceedings a comprehensive review of the recent progress in the field of nuclear reactor thermal-hydraulics worldwide. Individual papers have been cataloged separately.« less

  13. PREFACE: XIV Conference on Theoretical Nuclear Physics in Italy

    NASA Astrophysics Data System (ADS)

    Bombaci, I.; Covello, A.; Marcucci, L. E.; Rosati, S.

    2014-07-01

    This volume contains the invited and contributed papers presented at the 14th Conference on Theoretical Nuclear Physics in Italy held in Cortona, Italy, from 29-31 October, 2013. The meeting was held at the Palazzone, an elegant Renaissance Villa, commissioned by the Cardinal Silvio Passerini (1469-1529), Bishop of Cortona, and presently owned by the Scuola Normale Superiore di Pisa. The aim of this biennial Conference is to bring together Italian theorists working in various fields of nuclear physics to discuss their latest results and confront their points of view in a lively and informal way. This offers the opportunity to stimulate new ideas and promote collaborations between different research groups. The Conference was attended by 46 participants, coming from 13 Italian Universities and 11 Laboratories and Sezioni of the Istituto Nazionale di Fisica Nucleare - INFN. The program of the conference, prepared by the Organizing Committee (Ignazio Bombaci, Aldo Covello, Laura Elisa Marcucci and Sergio Rosati) focused on the following main topics: Few-Nucleon Systems Nuclear Structure Nuclear Matter and Nuclear Dynamics Relativistic Heavy Ion Collisions and Quark-Gluon Plasma Nuclear Astrophysics Nuclear Physics with Electroweak Probes Structure of Hadrons and Hadronic Matter. In the last session of the Conference there were two invited review talks related to experimental activities of great current interest. Giacomo De Angelis from the Laboratori Nazionali di Legnaro spoke about the INFN SPES radioactive ion beam project. Sara Pirrone, INFN Sezione di Catania, gave a talk on the symmetry energy and isospin physics with the CHIMERA detector. Finally, Mauro Taiuti (Università di Genova), National Coordinator of the INFN-CSN3 (Nuclear Physics Experiments), reported on the present status and future challenges of experimental nuclear physics in Italy. We gratefully acknowledge the financial support of INFN who helped make the conference possible. I Bombaci, A Covello, L E Marcucci, S Rosati

  14. Glass science tutorial: Lecture No. 7, Waste glass technology for Hanford

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kruger, A.A.

    1995-07-01

    This paper presents the details of the waste glass tutorial session that was held to promote knowledge of waste glass technology and how this can be used at the Hanford Reservation. Topics discussed include: glass properties; statistical approach to glass development; processing properties of nuclear waste glass; glass composition and the effects of composition on durability; model comparisons of free energy of hydration; LLW glass structure; glass crystallization; amorphous phase separation; corrosion of refractories and electrodes in waste glass melters; and glass formulation for maximum waste loading.

  15. Summary of sessions on nuclear astrophysics

    NASA Astrophysics Data System (ADS)

    Rolfs, C.

    In the minds of some there exists the patronizing belief that nuclear physics is a mature science. The same is not believed about nuclear astrophysics, which has been an active branch of astrophysics for over fifty years, but is now in the midst of an exciting revival in experimental and theoretical research around the world. The ultimate goal is to understand how nuclear processes generate the energy of stars over their lifetimes and, in doing so, synthesize heavier elements from the primordial hydrogen and helium produced in the Big Bang, which led to the expanding universe. Impressive progress has been made in this goal and this was rewarded. However, there are major puzzles, such as the solar neutrino problem to name just one, which challenge the fundaments of the field. To solve these problems, new nuclear physics data are needed employing novel experimental techniques such as radioactive ion beams and underground accelerator facilities. Without such new data, much of the work done so far will - in an optimistic view - be incomplete and - in a pessimistic view - be possibly wrong. Thus, new data do not represent a fine structure information or a cleaning-up job, but they represent the major next step in this exciting field&

  16. A Report of the Nuclear Engineering Division Sessions at the 1971 ASEE Annual Conference

    ERIC Educational Resources Information Center

    Eckley, Wayne; Nelson, George W.

    1972-01-01

    Summarizes the discussions at the conference under the topics, Objective Criteria for the Future" and Teaching Concepts Basic to Nuclear Engineering." Includes comments from personnel representing universities, industries, and government laboratories. (TS)

  17. Editorial note

    NASA Astrophysics Data System (ADS)

    Degueldre, Claude; Lee, Bill; Oversby, Virginia; van Walle, Eric

    2009-03-01

    The 3rd Symposium N on Nuclear Materials of the European Material Research Society (EMRS) held at the EMRS 08 Spring meeting; Strasbourg - May 26-30, 2008, involved 125 experts from 19 countries dealing with specific nuclear topics in the following sessions: Materials for advanced fusion systems.

  18. FOREWORD: International Summer School for Advanced Studies 'Dynamics of open nuclear systems' (PREDEAL12)

    NASA Astrophysics Data System (ADS)

    Delion, D. S.; Zamfir, N. V.; Raduta, A. R.; Gulminelli, F.

    2013-02-01

    This proceedings volume contains the invited lectures and contributions presented at the International Summer School on Nuclear Physics held at Trei Brazi, a summer resort of the Bioterra University, near the city of Predeal, Romania, on 9-20 July 2012. The long tradition of International Summer Schools on Nuclear Physics in Romania dates as far back as 1964, with the event being scheduled every two years. During this period of almost 50 years, many outstanding nuclear scientists have lectured on various topics related to nuclear physics and particle physics. This year we celebrate the 80th birthday of Aureliu Sandulescu, one of the founders of the Romanian school of theoretical nuclear physics. He was Serban Titeica's PhD student, one of Werner Heisenberg's PhD students, and he organized the first edition of this event. Aureliu Sandulescu's major contributions to the field of theoretical nuclear physics are related in particular to the prediction of cluster radioactivity, the physics of open quantum systems and the innovative technique of detecting superheavy nuclei using the double magic projectile 48Ca (Calcium), nowadays a widely used method at the JINR—Dubna and GSI—Darmstadt laboratories. The title of the event, 'Dynamics of Open Nuclear Systems', is in recognition of Aureliu Sandulescu's great personality. The lectures were attended by Romanian and foreign Master and PhD students and young researchers in nuclear physics. About 25 reputable professors and researchers in nuclear physics delivered lectures during this period. According to a well-established tradition, an interval of two hours was allotted for each lecture (including discussions). Therefore we kept a balance between the school and conference format. Two lectures were held during the morning and afternoon sessions. After lecture sessions, three or four oral contributions were given by young scientists. This was a good opportunity for them to present the results of their research in front of renowned professors and researchers in nuclear physics. This proceedings volume is organized into four chapters, which reflects the traditional chapter structure of nuclear physics textbooks, but seen from the perspective of open quantum systems: INuclear structure IIDecay processes IIINuclear reactions and astrophysics IVContributions The lectures and contributions are listed alphabetically by author within each chapter. The volume contains many comprehensive reviews related to the topics of the School. The first week of the School was focused on nuclear structure and decay phenomena, considering the nucleus as an open system. Experts in these fields lectured on cluster radioactivity, the stability of superheavy nuclei, alpha-decay fine structure, fission versus fusion, beta and double beta decay and pairing versus alpha-clustering. New experimental results related to the nuclear stability of low-lying and high spin states were also presented. Recent developments at JINR—Dubna and GSI—Darmstadt international laboratories were also reported by their current or former directors. The second week of the event was dedicated to the physics of exotic nuclei, heavy ion reactions and multi-fragmentation, symmetries and phase transitions of open quantum systems. The stability of the atomic nucleus is an important and always interesting discussion point, especially in the context of newly discovered nuclear systems close to the stability line, such as proton/neutron rich or superheavy nuclei. Several lectures and contributions were focused on nuclear structure models describing low-lying states. This includes the status of density functional theory, new developments in Bohr-Mottelsohn Hamiltonian and shell-model theory, proton-neutron correlations, shape coexistence, back-bending phenomena and the thermodynamics of open quantum systems. Open systems in astrophysics, such as supernovae and neutron stars, were presented in detail by several lecturers. Important topics connected to the status of the equation of state, hyperonic and quark matter and neutrino physics, as well as the applications of nuclear structure in astrophysics, were also on the School's agenda. There were many discussions and questions both during and after presentations. An open and friendly atmosphere characterized our School, although different opinions quite often divided the participants. Many discussions continued during coffee breaks and excursions organized in the beautiful surroundings. We hope that this proceedings volume will be useful for future reference to both young scientists and senior researchers working in various fields of nuclear physics. We cannot end without expressing our many thanks to the National Authority for Scientific Research and the Romanian Academy (Elias Foundation) for their financial support. We acknowledge the Horia Hulubei National Institute of Physics and Nuclear Engineering and Bioterra University for their important contribution in organizing the School. Guest Editors D S Delion, N V Zamfir, A R Raduta and F Gulminelli First Week International Summer School on Nuclear Physics: First Week Second Week International Summer School on Nuclear Physics: Second Week Sponsors Sponsor logoSponsor logoSponsor logoSponsor logoSponsor logo

  19. The U. S. Department of Energy SARP review training program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mauck, C.J.

    1988-01-01

    In support of its radioactive material packaging certification program, the U.S. Department of Energy (DOE) has established a special training workshop. The purpose of the two-week workshop is to develop skills in reviewing Safety Analysis Reports for Packagings (SARPs) and performing confirmatory analyses. The workshop, conducted by the Lawrence Livermore National Laboratory (LLNL) for DOE, is divided into two parts: methods of review and methods of analysis. The sessions covering methods of review are based on the DOE document, ''Packaging Review Guide for Reviewing Safety Analysis Reports for Packagings'' (PRG). The sessions cover relevant DOE Orders and all areas ofmore » review in the applicable Nuclear Regulatory Commission (NRC) Regulatory Guides. The technical areas addressed include structural and thermal behavior, materials, shielding, criticality, and containment. The course sessions on methods of analysis provide hands-on experience in the use of calculational methods and codes for reviewing SARPs. Analytical techniques and computer codes are discussed and sample problems are worked. Homework is assigned each night and over the included weekend; at the conclusion, a comprehensive take-home examination is given requiring six to ten hours to complete.« less

  20. Multi-modality Imaging: Bird's eye view from the 2015 American Heart Association Scientific Sessions.

    PubMed

    Einstein, Andrew J; Lloyd, Steven G; Chaudhry, Farooq A; AlJaroudi, Wael A; Hage, Fadi G

    2016-04-01

    Multiple novel studies were presented at the 2015 American Heart Association Scientific Sessions which was considered a successful conference at many levels. In this review, we will summarize key studies in nuclear cardiology, cardiac magnetic resonance, echocardiography, and cardiac computed tomography that were presented at the Sessions. We hope that this bird's eye view will keep readers updated on the newest imaging studies presented at the meeting whether or not they were able to attend the meeting.

  1. PREFACE: XXXVII Brazilian Meeting on Nuclear Physics

    NASA Astrophysics Data System (ADS)

    2015-07-01

    The XXXVII Brazilian Meeting on Nuclear Physics (or XXXVII RTFNB 2014) gave continuity to a long sequence of workshops held in Brazil, devoted to the study of the different aspects of nuclear physics. The meeting took place in the Maresias Beach Hotel, in the town of Maresias (state of São Paulo) from 8th to 12th September 2014. Offering gentle weather, a charming piece of green land of splendid natural beauty with beach and all amenities, the place had all the conditions for very pleasant and fruitful discussions. The meeting involved 162 participants and attracted undergraduate and graduate students, Brazilian and South American physicists and invited speakers from overseas (USA, Italy, Spain, France, England, Switzerland, Germany and South Corea). In the program we had plenary morning sessions with review talks on recent developments in theory, computational techniques, experimentation and applications of the many aspects of nuclear physics. In the parallel sessions we had a total of 58 seminars. This volume contains 60 written contributions based on these talks and on the poster sessions. Evening talks and poster sessions gave still more insight and enlarged the scope of the scientific program. The contributed papers, representing mainly the scientific activity of young physicists, were exhibited as posters and are included in the present volume. Additional information about the meeting can be found at our website: http://www.sbfisica.org.br/~rtfnb/xxxvii-en Support and sponsorship came from brazilian national agencies: Conselho Nacional de Desenvolvimento Científico e Tecnoógico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo á Pesquisa do Estado de São Paulo (FAPESP); Fundação de Amparo á Pesquisa do Estado do Rio de Janeiro (FAPERJ); Sociedade Brasileira de Física (SBF) and Instituto de Física da Universidade de São Paulo (IFUSP). We honored Professor Alejandro Szanto de Toledo, who completed fifty years of scientific activities at the University of Sao Paulo (USP). He dedicated most of his life to the development of experimental nuclear physics in the country. We had a special session where his life and achievements were remembered. The organization of the XXXVII RTFNB 2014 was one more step in a big effort to build in our part of the world a community of physicists engaged in the difficult problems of fundamental and applied nuclear physics. The international contacts bring new knowledge, provide reference framework and stimulate collaborations that are essential for a true participation in the scientific frontier. The Editors, the Organizing Committee and the whole Brazilian community of nuclear physicists were pleased and very grateful to the visitors that were together with us during the five days in Maresias. The Editors

  2. Plutonium immobilization in glass and ceramics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Knecht, D.A.; Murphy, W.M.

    1996-05-01

    The Materials Research Society Nineteenth Annual Symposium on the Scientific Basis for Nuclear Waste Management was held in Boston on November 27 to December 1, 1995. Over 150 papers were presented at the Symposium dealing with all aspects of nuclear waste management and disposal. Fourteen oral sessions and on poster session included a Plenary session on surplus plutonium dispositioning and waste forms. The proceedings, to be published in April, 1996, will provide a highly respected, referred compilation of the state of scientific development in the field of nuclear waste management. This paper provides a brief overview of the selected Symposiummore » papers that are applicable to plutonium immobilization and plutonium waste form performance. Waste forms that were described at the Symposium cover most of the candidate Pu immobilization options under consideration, including borosilicate glass with a melting temperature of 1150 {degrees}C, a higher temperature (1450 {degrees}C) lanthanide glass, single phase ceramics, multi-phase ceramics, and multi-phase crystal-glass composites (glass-ceramics or slags). These Symposium papers selected for this overview provide the current status of the technology in these areas and give references to the relevant literature.« less

  3. Results from the 2010 INMM International Containment and Surveillance Workshop focused on Concepts for the 21st Century

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pickett, Chris A; Tolk, Keith M; Keel, Frances M

    2010-01-01

    The Institute of Nuclear Materials Management (INMM) held an International Workshop, 'Containment & Surveillance (C/S): Concepts for the 21st Century,' June 6-11, 2010, at the Oak National Laboratory, in Oak Ridge, Tennessee. The National Nuclear Security Administration (NNSA) Office of Nonproliferation Research and Development and Office of Nonproliferation and International Security sponsored the event. The workshop focused on determining concepts and needs for 21st century containment and surveillance (C/S) systems that support International Atomic Energy Agency (IAEA) safeguards and future arms control agreements. Panel discussions by subject matter experts and international practitioners addressed daily topical themes encompassing the following areasmore » of C/S: authentication; tagging, sealing, and containment verification; and surveillance systems. Each panel discussion was followed by a question-and-answer session with the audience and an afternoon breakout session. The facilitated breakout sessions were used to compile information and determine future needs. Individuals attending the workshop included C/S experts and practitioners; IAEA and arms control inspectors; technology providers; vendors; students; and individuals with an interest in, or desire to learn about, future C/S system needs. The primary goal of the workshop was to produce a document that details the future research and development needs for C/S systems that support nuclear safeguards and arms control missions. This talk will present a compilation of the information obtained from breakout sessions at the workshop.« less

  4. Sensitivity Analysis in Engineering

    NASA Technical Reports Server (NTRS)

    Adelman, Howard M. (Compiler); Haftka, Raphael T. (Compiler)

    1987-01-01

    The symposium proceedings presented focused primarily on sensitivity analysis of structural response. However, the first session, entitled, General and Multidisciplinary Sensitivity, focused on areas such as physics, chemistry, controls, and aerodynamics. The other four sessions were concerned with the sensitivity of structural systems modeled by finite elements. Session 2 dealt with Static Sensitivity Analysis and Applications; Session 3 with Eigenproblem Sensitivity Methods; Session 4 with Transient Sensitivity Analysis; and Session 5 with Shape Sensitivity Analysis.

  5. Concerns over modeling and warning capabilities in wake of Tohoku Earthquake and Tsunami

    NASA Astrophysics Data System (ADS)

    Showstack, Randy

    2011-04-01

    Improved earthquake models, better tsunami modeling and warning capabilities, and a review of nuclear power plant safety are all greatly needed following the 11 March Tohoku earthquake and tsunami, according to scientists at the European Geosciences Union's (EGU) General Assembly, held 3-8 April in Vienna, Austria. EGU quickly organized a morning session of oral presentations and an afternoon panel discussion less than 1 month after the earthquake and the tsunami and the resulting crisis at Japan's Fukushima nuclear power plant, which has now been identified as having reached the same level of severity as the 1986 Chernobyl disaster. Many of the scientists at the EGU sessions expressed concern about the inability to have anticipated the size of the earthquake and the resulting tsunami, which appears likely to have caused most of the fatalities and damage, including damage to the nuclear plant.

  6. Proceedings of the 21st DOE/NRC Nuclear Air Cleaning Conference; Sessions 1--8

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    First, M.W.

    1991-02-01

    Separate abstracts have been prepared for the papers presented at the meeting on nuclear facility air cleaning technology in the following specific areas of interest: air cleaning technologies for the management and disposal of radioactive wastes; Canadian waste management program; radiological health effects models for nuclear power plant accident consequence analysis; filter testing; US standard codes on nuclear air and gas treatment; European community nuclear codes and standards; chemical processing off-gas cleaning; incineration and vitrification; adsorbents; nuclear codes and standards; mathematical modeling techniques; filter technology; safety; containment system venting; and nuclear air cleaning programs around the world. (MB)

  7. PREFACE: XX International School on Nuclear Physics, Neutron Physics and Applications (Varna2013)

    NASA Astrophysics Data System (ADS)

    Stoyanov, Chavdar; Dimitrova, Sevdalina

    2014-09-01

    The present volume contains the lectures and short talks given at the XX International School on Nuclear Physics, Neutron Physics and Applications. The School was held from 16-22 September 2013 in 'Club Hotel Bolero' located in 'Golden Sands' (Zlatni Pyasaci) Resort Complex on the Black Sea coast, near Varna, Bulgaria. The School was organized by the Institute for Nuclear Research and Nuclear Energy of Bulgarian Academy of Sciences. Co-organizer of the School was the Bulgarian Nuclear Regulatory Agency and the Bogoliubov Laboratory of Theoretical Physics of Joint Institute for Nuclear Research - Dubna. Financial support was also provided by the Bulgarian Ministry of Education and Science. According to the long-standing tradition the School has been held every second year since 1973. The School's program has been restructured according to our enlarged new international links and today it is more similar to an international conference than to a classical nuclear physics school. This new image attracts many young scientists and students from around the world. This year, 2013, we had the pleasure to welcome more than sixty distinguished scientists as lecturers. Additionally, twenty young colleagues received the opportunity to present a short contribution. Ninety-four participants altogether enjoyed the scientific presentations and discussions as well as the relaxing atmosphere at the beach and during the pleasant evenings. The program of the School ranged from latest results in fundamental areas such as nuclear structure and reactions to the hot issues of application of nuclear methods, reactor physics and nuclear safety. The main topics have been the following: Nuclear excitations at various energies. Nuclei at high angular moments and temperature. Structure and reactions far from stability. Symmetries and collective phenomena. Methods for lifetime measurements. Astrophysical aspects of nuclear structure. Neutron nuclear physics. Nuclear data. Advanced methods in nuclear waste treatment. Nuclear methods for applications. A special session in honor of the late Mario Stoitsov, was also part of the program. Many colleagues of Mario from all over the world came to Varna to pay tribute to this prominent scientist and loyal friend. Several colleagues contributed to the organization of the School. We would like to thank them and especially the Scientific Secretary of the School Dr Elena Stefanova and the members of the Organizing Committee Dr Dimitar Tarpanov and Peter Zivkov for their cordiality and high level assistance. We are also grateful to Dr Jacek Dobaczewski, who reached out to the collaborators of Mario Stoitsov on behalf of the conference. Sofia, 20 March 2014 Co-chair persons of the Organizing Committee Prof Dr Sc Ch Stoyanov Prof Dr Sc S Dimitrova Details of the committees are available in the PDF.

  8. From a United Nations Study: The Climatic and Other Global Effects of Nuclear War.

    ERIC Educational Resources Information Center

    Environment, 1988

    1988-01-01

    Presents excerpts from the first chapter of a report presented to the General Assembly of the United Nations during the Special Session on Disarmament. Discussed are key scientific issues regarding the global effects of nuclear war, and the findings and conclusions presented in the report. (CW)

  9. Multi-modality imaging: Bird's-eye view from the 2014 American Heart Association Scientific Sessions.

    PubMed

    AlJaroudi, Wael A; Einstein, Andrew J; Chaudhry, Farooq A; Lloyd, Steven G; Hage, Fadi G

    2015-04-01

    A large number of studies were presented at the 2014 American Heart Association Scientific Sessions. In this review, we will summarize key studies in nuclear cardiology, computed tomography, echocardiography, and cardiac magnetic resonance imaging. This brief review will be helpful for readers of the Journal who are interested in being updated on the latest research covering these imaging modalities.

  10. PREFACE: 10th International Conference on Clustering Aspects of Nuclear Structure and Dynamics (CLUSTER'12)

    NASA Astrophysics Data System (ADS)

    Lovas, R. G.; Dombrádi, Zs; Kiss, G. G.; Kruppa, A. T.; Lévai, G.

    2013-04-01

    As Editors of this Proceedings volume and organizers as well as participants of the Conference, let us sum up a few facts about the Conference and let us add some subjective notes. The conference was held at Köolcsey Centre, a prestigious site of scientific and business meetings and cultural events in the city of Debrecen, Hungary, 24-28 September 2012. The city was chosen as the home of the Institute of Nuclear Research of the Hungarian Academy of Sciences, the home institution of the organizers. The Institute was visited by some of the participants. The organizing team was complemented by some belonging to the University of Debrecen, which made it possible to hold the conference dinner in the marvellous covered 'ceremonial court' of the University. The participants were taken for an excursion and wine tasting to a wine cellar at Tokaj, centre of, historically, the most significant wine producing area in Hungary. By coincidence, the closing day coincided with the day of what is called the Researchers' Night in the European Union. That night, (or rather, that evening) every year there is a public lecture in the Institute of Nuclear Research for a general audience, mainly secondary-school pupils. The public lecture scheduled on this occasion was held by one of the participants of the conference who represented the world outside Hungary and yet was able to deliver a talk in Hungarian. He is Professor Kálmán Varga, Vanderbilt University. The title of his talk was Simulation of Nanosystems ( http://kutatokejszakaja.hu/2012/esemenynaptar/esemeny.php?id=112&menu_id=4). There were 115 registered participants, representing 22 countries of Europe, Africa, Asia, Central, South and North America. We had 44 plenary talks and 47 talks presented in parallel sessions. In the Programme list the talks are arranged following the session structure of the Conference. In this list the invited speakers are marked by asterisks. All the talks in the plenary sessions were invited talks, but we had some invited talks even in the parallel sessions. Written versions of 86 talks have been submitted. Quite a number of the speakers have modified the title of their talk in the written version. To keep the correspondence between the Programme list and the written papers, we have accordingly changed the titles in the Programme list as well. The papers are arranged according to their subjects, without regard to whether they were delivered in a plenary or in a parallel session. There was a talk classified wrongly; this is now classified correctly. In the Programme list and in the list of the papers submitted the names are those of the speakers. You can read in the Opening Address that, by ruling of the organizing institution, no members of the Debrecen Institute of Nuclear Research were selected as invited speakers and no contributions were accepted from them. We doubted the wisdom of this rigour ourselves, and I think the criticism we received for it is justifiable. The success of a conference depends primarily on the speakers. In retrospect, we can say that this conference was extremely successful, and that is owing to the great many wonderful talks delivered. This reflects very well on the present status of the field as well as on the work of the International Advisory Board, which proposed the list of excellent speakers. The Japanese dominance characteristic of all cluster conferences has only been complained about by some of the Japanese who came to Europe primarily to learn things that they could not learn at home. We would like to express our gratitude to our sponsors: the Hungarian Academy of Sciences the Paks Nuclear Power Ltd HMP Logic Ltd International Workshop for Theoretical Physics(Budapest) We were also supported indirectly by a JSPS-MTA bilateral cooperation project, which made it possible for five Japanese colleagues to participate. It just remains to be announced that the next, number 11 in this series of conferences, will be held in Naples in 2016. Zs Dombrádi G G Kiss A T Kruppa G Lévai R G Lovas Conference photograph

  11. PREFACE: 12th Conference on ''Theoretical Nuclear Physics in Italy''

    NASA Astrophysics Data System (ADS)

    Bombaci, I.; Covello, A.; Marcucci, L. E.; Rosati, S.

    2009-07-01

    These Proceedings contain the invited and contributed papers presented at the 12th Conference on Theoretical Nuclear Physics in Italy held in Cortona, Italy, from 8-10 October 2008. As usual, the meeting was held at il Palazzone, a 16th century castle owned by the Scuola Normale Superiore di Pisa. The aim of this biennal conference is to bring together Italian theorists working in various fields of Nuclear Physics to discuss their latest results and confront their points of view in a lively and informal way. This offers the opportunity to promote collaborations between different groups. There were about 50 participants at the conference, coming from 14 Italian Universities (Cagliari, Catania, Ferrara, Firenze, Genova, Lecce, Milano, Napoli, Padova, Pavia, Pisa, Roma, Trento, Trieste). The program of the conference, prepared by the Organizing Committee (Ignazio Bombaci, Aldo Covello, Laura Elisa Marcucci and Sergio Rosati) focused on six main topics: Few-Nucleon Systems, Nuclear Matter and Nuclear Dynamics, Nuclear Astrophysics, Structure of Hadrons and Hadronic Matter, Nuclear Structure, Nuclear Physics with Electroweak Probes. Winfried Leidemann, Maria Colonna, Marcello Lissia, Elena Santopinto, Silvia Lenzi and Omar Benhar took the burden of giving general talks on these topics and reviewing the research activities of the various Italian groups. In addition, 19 contributed papers were presented, most of them by young participants. In the last session of the Conference there were two invited talks related to experimental activities of great current interest. Gianfranco Prete from the Laboratori Nazionali di Legnaro spoke about the Italian radioactive ion beam facility SPES and the status of the European project EURISOL, while Nicola Colonna from the INFN, Bari, gave an overview of the perspectives of development of fourth-generation nuclear reactors. We would like to thank the authors of the general reports for their hard work in reviewing the main achievements in the various fields as well as our experimental colleagues for having kindly agreed to talk to an audience consisting only of theoretical physicists. I Bombaci, A Covello, L E Marcucci and S Rosati

  12. Structure and Activities of Nuclear Medicine in Kuwait.

    PubMed

    Elgazzar, Abdelhamid H; Owunwanne, Azuwuike; Alenezi, Saud

    2016-07-01

    The practice of nuclear medicine in Kuwait began in 1965 as a clinic for treating thyroid diseases. The practice developed gradually and until 1981 when the Faculty of Medicine established the Division of Nuclear Medicine in the Department of Radiology, which later became a separate department responsible for establishing and managing the practice in all hospitals of Kuwait. In 1987, a nuclear medicine residency program was begun and it is administered by Kuwait Institute for Medical Specializations originally as a 4-year but currently as a 5-year program. Currently there are 11 departments in the ministry of health hospitals staffed by 49 qualified attending physicians, mostly the diplomats of the Kuwait Institute for Medical Specializations nuclear medicine residency program, 4 academic physicians, 2 radiopharmacists, 2 physicists, and 130 technologists. These departments are equipped with 33 dual-head gamma cameras, 10 SPET/CT, 5 PET/CT, 2 cyclotrons, 1 breast-specific gamma imaging, 1 positron-emitting mammography, 10 thyroid uptake units, 8 technegas machines, 7 PET infusion systems, and 8 treadmills. Activities of nuclear medicine in Kuwait include education and training, clinical service, and research. Education includes nuclear medicine technology program in the Faculty of Allied Health Sciences, the 5-year residency program, medical school teaching distributed among different modules of the integrated curriculum with 14 didactic lecture, and other teaching sessions in nuclear medicine MSc program, which run concurrently with the first part of the residency program. The team of Nuclear Medicine in Kuwait has been active in research and has published more than 300 paper, 11 review articles, 12 book chapters, and 17 books in addition to 36 grants and 2 patents. A PhD program approved by Kuwait University Council would begin in 2016. Copyright © 2016 Elsevier Inc. All rights reserved.

  13. Editorial to NIM-B

    NASA Astrophysics Data System (ADS)

    McDaniel, Floyd Del; Doyle, Barney L.; Glass, Gary; Wang, Yongqiang; Antolak, Arlyn

    2018-01-01

    This special issue of Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms contains 7 selected papers that were presented at the 24th International Conference on the Application of Accelerators in Research and Industry (CAARI 2016). This conference was held in Fort Worth, Texas, USA, October 30 - November 4, 2016 and the Worthington Renaissance Hotel. CAARI 2016 had 5 plenary sessions, 79 oral sessions, 2 poster sessions, 401 presentations (10 plenary talks, 165 invited talks, 154 contributed talks, and 72 poster presentations), and 434 attendees (76 of which were students and 14 were accompanying persons) from 32 countries.

  14. Nuclear Data Needs and Capabilities for Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brown, D.

    2015-05-27

    In July 2014, DOE NP carried out a review of the US Nuclear Data Program. This led to several recommendations, including that the USNDP should “devise effective and transparent mechanisms to solicit input and feedback from all stakeholders on nuclear data needs and priorities.” The review also recommended that USNDP pursue experimental activities of relevance to nuclear data; the revised 2014 Mission Statement accordingly states that the USNDP uses “targeted experimental studies” to address gaps in nuclear data. In support of these recommendations, DOE NP requested that USNDP personnel organize a Workshop on Nuclear Data Needs and Capabilities for Applicationsmore » (NDNCA). This Workshop was held at Lawrence Berkeley National Laboratory (LBNL) on 27-29 May 2015. The goal of the NDNCA Workshop was to compile nuclear data needs across a wide spectrum of applied nuclear science, and to provide a summary of associated capabilities (accelerators, reactors, spectrometers, etc.) available for the required measurements. The first two days of the workshop consisted of 25 plenary talks by speakers from 16 different institutions, on nuclear energy (NE), national security (NS), isotope production (IP), and industrial applications (IA). There were also shorter “capabilities” talks that described the experimental facilities and instrumentation available for the measurement of nuclear data. This was followed by a third day of topic-specific “breakout” sessions and a final closeout session. The agenda and copies of these talks are available online at http://bang.berkeley.edu/events/NDNCA/agenda. The importance of nuclear data to both basic and applied nuclear science was reflected in the fact that while the impetus for the workshop arose from the 2014 USNDP review, joint sponsorship for the workshop was provided by the Nuclear Science and Security Consortium, a UC-Berkeley based organization funded by the National Nuclear Security Administration (NNSA).« less

  15. Developing a taxonomy of coordination behaviours in nuclear power plant control rooms during emergencies.

    PubMed

    Wang, Dunxing; Gao, Qin; Li, Zhizhong; Song, Fei; Ma, Liang

    2017-12-01

    This study aims to develop a taxonomy of coordination behaviours during emergencies in nuclear power plants (NPPs). We summarised basic coordination behaviours from literature in aviation, health care and nuclear field and identified coordination behaviours specific to the nuclear domain by interviewing and surveying control crew operators. The established taxonomy includes 7 workflow stages and 24 basic coordination behaviours. To evaluate the reliability and feasibility of the taxonomy, we analysed 12 videos of operators' training sessions by coding coordination behaviours with the taxonomy and the inter-rater reliability was acceptable. Further analysis of the frequency, the duration and the direction of the coordination behaviours revealed four coordination problems. This taxonomy provides a foundation of systematic observation of coordination behaviours among NPP crews, advances researchers' understanding of the coordination mechanism during emergencies in NPPs and facilitate the possibility to deepen the understanding of the relationships between coordination behaviours and team performance. Practitioner Summary: A taxonomy of coordination behaviours during emergencies in nuclear power plants was developed. Reliability and feasibility of the taxonomy was verified through the analysis of 12 training sessions. The taxonomy can serve as an observation system for analysis of coordination behaviours and help to identify coordination problems of control crews.

  16. Intelligence briefing on smuggling of nuclear material and the role of international crime organizations, and on the proliferation of cruise and ballistic missiles. Hearing before the Committee on Armed Services, United States Senate, One Hundred Fourth Congress, First Session, January 31, 1995

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    The hearing addresses nuclear smuggling and the role of international crime organizations in the proliferation of cruise and ballistic missiles. The demise of the Soviet Union has weakened the control in Russia over nuclear materials. Statements of government officials are included along with documents submitted for the record.

  17. Promoting Intercultural Competency in the Nuclear Workplace

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bachner K. M.

    Intercultural preparedness training is a staple of many workplaces that require international competence, including government, business, and non-profits. Even highly experienced diplomats are often advised to attend training sessions on this topic. Intercultural preparedness training promises to be especially relevant and useful for professionals working in the field of nuclear nonproliferation, including in the application of international nuclear safeguards. This paper outlines the fundamental philosophies underlying a training program that will benefit professionals in the nuclear arena, whether practitioners of nonproliferation or other sub-fields relying on international cooperation and collaboration, and how such a training program might be implemented efficiently.

  18. Nuclear Proliferation Factbook. Prepared for the Subcommittees on Arms Control, International Security and Science and on International Economic Policy and Trade of the Committee on Foreign Affairs, U.S. House of Representatives and the Subcommittee on Energy, Nuclear Proliferation, and Federal Processes of the Committee on Governmental Affairs, U.S. Senate, 99th Congress, 1st session.

    ERIC Educational Resources Information Center

    Library of Congress, Washington, DC. Congressional Research Service.

    To provide a handy reference for those concerned with ways to avoid the further spread, or proliferation, of nuclear weapons, the House Committee on Foreign Affairs and the Senate Committee on Governmental Affairs have since 1977 sponsored periodic publication of the Nuclear Proliferation Factbook. This fourth edition of the factbook includes a…

  19. "Structure and dynamics in complex chemical systems: Gaining new insights through recent advances in time-resolved spectroscopies.” ACS Division of Physical Chemistry Symposium presented at the Fall National ACS Meeting in Boston, MA, August 2015

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Crawford, Daniel

    8-Session Symposium on STRUCTURE AND DYNAMICS IN COMPLEX CHEMICAL SYSTEMS: GAINING NEW INSIGHTS THROUGH RECENT ADVANCES IN TIME-RESOLVED SPECTROSCOPIES. The intricacy of most chemical, biochemical, and material processes and their applications are underscored by the complex nature of the environments in which they occur. Substantial challenges for building a global understanding of a heterogeneous system include (1) identifying unique signatures associated with specific structural motifs within the heterogeneous distribution, and (2) resolving the significance of each of multiple time scales involved in both small- and large-scale nuclear reorganization. This symposium focuses on the progress in our understanding of dynamics inmore » complex systems driven by recent innovations in time-resolved spectroscopies and theoretical developments. Such advancement is critical for driving discovery at the molecular level facilitating new applications. Broad areas of interest include: Structural relaxation and the impact of structure on dynamics in liquids, interfaces, biochemical systems, materials, and other heterogeneous environments.« less

  20. From Confrontation to Cooperation: 8th International Seminar on Nuclear War

    NASA Astrophysics Data System (ADS)

    Zichichi, A.; Dardo, M.

    1992-09-01

    The Table of Contents for the full book PDF is as follows: * OPENING SESSION * A. Zichichi: Opening Statements * R. Nicolosi: Opening Statements * MESSAGES * CONTRIBUTIONS * "The Contribution of the Erice Seminars in East-West-North-South Scientific Relations" * 1. LASER TECHNOLOGY * "Progress in laser technology" * "Progress in laboratory high gain ICF: prospects for the future" * "Applications of laser in metallurgy" * "Laser tissue interactions in medicine and surgery" * "Laser fusion" * "Compact X-ray lasers in the laboratory" * "Alternative method for inertial confinement" * "Laser technology in China" * 2. NUCLEAR AND CHEMICAL SAFETY * "Reactor safety and reactor design" * "Thereotical analysis and numerical modelling of heat transfer and fuel migration in underlying soils and constructive elements of nuclear plants during an accident release from the core" * "How really to attain reactor safely" * "The problem of chemical weapons" * "Long terms genetic effects of nuclear and chemical accidents" * "Features of the brain which are of importance in understanding the mode of operation of toxic substances and of radiation" * "CO2 and ultra safe reactors" * 3. USE OF MISSILES * "How to convert INF technology for peaceful scientific purposes" * "Beating words into plowshares: a proposal for the peaceful uses of retired nuclear warheads" * "Some thoughts on the peaceful use of retired nuclear warheads" * "Status of the HEFEST project" * 4. OZONE * "Status of the ozone layer problem" * 5. CONVENTIONAL AND NUCLEAR FORCE RESTRUCTURING IN EUROPE * 6. CONFLICT AVOIDANCE MODEL * 7. GENERAL DISCUSSION OF THE WORLD LAB PROJECTS * "East-West-North-South Collaboration in Subnuclear Physics" * "Status of the World Lab in the USSR" * CLOSING SESSION

  1. 76 FR 28425 - Sunshine Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-17

    ..., emergency preparedness, and nuclear materials disposition. During Session I, the Board will receive... reduce risk in the tank farms. The Board will examine the state of emergency preparedness at the Site and...

  2. Instituting Nuclear Age Education: Towards a Cooperative Future. Proceedings of the International Student Pugwash Symposium (Atlanta, Georgia, January 20-23, 1983). [Summary].

    ERIC Educational Resources Information Center

    International Student Pugwash, Washington, DC.

    Proceedings of a symposium which focused on issues related to nuclear weapons and arms control are presented. In addition to a list of participants (including both high school and college educators) and symposium schedule, summaries/highlights of symposium sessions are provided. These include summaries of three working groups which discussed…

  3. 77 FR 55196 - Sunshine Act Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-07

    ... Nuclear Security Administration's oversight for these activities, and the status of site-wide emergency preparedness. That session will be rescheduled as a separate open meeting and hearing at a time and place to be...

  4. Insider Threat to Computer Security at Nuclear Facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    West, Rebecca Lynn

    After completing this session, you should be able to: Describe the Insider Threat; Characterize the cyber insider threat; Describe preventive measures against the insider threat; Describe protective measures against the insider threat.

  5. Nineteenth International Cosmic Ray Conference. OG Sessions, Volume 3

    NASA Technical Reports Server (NTRS)

    Jones, F. C. (Compiler)

    1985-01-01

    Papers submitted for presentation at the 19th International Cosmic Ray Conference are compiled. This volume addresses cosmic ray sources and acceleration, interstellar propagation and nuclear interactions, and detection techniques and instrumentation.

  6. Panel session on "safety, health and the environment: implications of nuclear power growth".

    PubMed

    Bilbao y León, Sama

    2011-01-01

    This paper summarizes the presentations and the insights offered by panelists John P. Winston, Robert Bernero, and Stephen LaMontagne during the Panel on Safety, Health and the Environment: Implications of Nuclear Power Growth that took place during the NCRP 2009 Annual Meeting. The paper describes the opportunities and the challenges faced in the areas of infrastructure development, radiation control, licensing and regulatory issues, and non-proliferation as a consequence of the forecasted growth in nuclear power capacity worldwide. Copyright © 2010 Health Physics Society

  7. A little something from physics for medicine (Scientific session of the Physical Sciences Division of the Russian Academy of Sciences, 23 April 2014)

    NASA Astrophysics Data System (ADS)

    2014-12-01

    A scientific session of the Physical Sciences Division of the Russian Academy of Sciences (RAS), entitled "A little something from physics for medicine", was held on 23 April 2014 at the conference hall of the Lebedev Physical Institute, RAS. The agenda posted on the website of the Physical Sciences Division, RAS, http://www.gpad.ac.ru, included the following reports: (1) Rumyantsev S A (D Rogachev Federal Research and Clinical Center of Pediatric Hematology, Oncology, and Immunology, Moscow) "Translational medicine as a basis of progress in hematology/oncology"; (2) Akulinichev S V (Institute for Nuclear Research, RAS, Moscow) "Promising nuclear medicine research at the INR, RAS"; (3) Nikitin P P (Prokhorov General Physics Institute, RAS, Moscow) "Biosensorics: new possibilities provided by marker-free optical methods and magnetic nanoparticles for medical diagnostics"; (4) Alimpiev S S, Nikiforov S M, Grechnikov A A (Prokhorov General Physics Institute, RAS, Moscow) "New approaches in laser mass-spectrometry of organic objects". The publication of the article based on the oral report No. 2 is presented below. • Promising nuclear medicine research in the Institute for Nuclear Research, Russian Academy of Sciences, V V Akulinichev Physics-Uspekhi, 2014, Volume 57, Number 12, Pages 1239-1243

  8. Footprints in the Woods:"Tracking" a Nursery Child through a Forest School Session

    ERIC Educational Resources Information Center

    Mackinder, Melanie

    2017-01-01

    Forest School has become increasingly popular in the UK, although little is known about what actually happens in sessions and how these sessions are planned. Using observations of two sessions and semi-structured interviews with two adult leaders this article sets out to explore how the sessions are planned, alongside a young child (aged 2-4…

  9. Nuclear regulatory legislation: 102d Congress. Volume 1, No. 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1993-10-01

    This document is a compilation of nuclear regulatory legislation and other relevant material through the 102d Congress, 2d Session. This compilation has been prepared for use as a resource document, which the NRC intends to update at the end of every Congress. The contents of NUREG-0980 include: The Atomic Energy Act of 1954, as amended; Energy Reorganization Act of 1974, as amended, Uranium Mill Tailings Radiation Control Act of 1978; Low-Level Radioactive Waste Policy Act; Nuclear Waste Policy Act of 1982; and NRC Authorization and Appropriations Acts. Other materials included are statutes and treaties on export licensing, nuclear non-proliferation, andmore » environmental protection.« less

  10. Nuclear regulatory legislation, 102d Congress. Volume 2, No. 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1993-10-01

    This document is a compilation of nuclear regulatory legislation and other relevant material through the 102d Congress, 2d Session. This compilation has been prepared for use as a resource document, which the NRC intends to update at the end of every Congress. The contents of NUREG-0980 include The Atomic Energy Act of 1954, as amended; Energy Reorganization Act of 1974, as amended, Uranium Mill Tailings Radiation Control Act of 1978; Low-Level Radioactive Waste Policy Act; Nuclear Waste Policy Act of 1982; and NRC Authorization and Appropriations Acts. Other materials included are statutes and treaties on export licensing, nuclear non-proliferation, andmore » environmental protection.« less

  11. 1979 New Mexico legislative session: energy issues and legislation. [WIPP

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barsumian, L.; Vandevender, S.G.

    1979-10-01

    This report is an account of the energy legislation and associated issues considered during the 1979 session of the 34th New Mexico Legislature. The session's major issue was the federal study of a proposed nuclear Waste Isolation Pilot Plant (WIPP) in New Mexico. A large proportion of time and effort was spent on resolving the state's formal position toward the federal project. However, other energy concerns were also significant even though they were neither as controversial nor as visible as the primary issue. The two most important laws enacted were the Radioactive Waste Consultation Act and the Radioactive Waste Transportationmore » Act. The Legislature considered 47 other energy-related bills, of which 17 were enacted.« less

  12. Nuclear safety: is NRC enforcement working. Hearing before a Subcommittee of the Committee on Government Operations, House of Representatives, Ninety-Seventh Congress, First Session, December 14, 1981

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    Nunzio Palladino, the new Chairman of the Nuclear Regulatory Commission, and associates testified at this hearing on the effectiveness of NRC's enforcement program and responded to allegations that quality assurance is inadequate. At issue were the value of NRC fines as a deterrent to utility misconduct and the NRC's reluctance to pursue new provisions for criminal penalties. Mr. Palladino was welcomed and applauded for his strong statements on the nuclear industry's need for strict quality control. (DCK)

  13. Effects of "minimally invasive curricular surgery" - a pilot intervention study to improve the quality of bedside teaching in medical education.

    PubMed

    Raupach, Tobias; Anders, Sven; Pukrop, Tobias; Hasenfuss, Gerd; Harendza, Sigrid

    2009-09-01

    Bedside teaching is an important element of undergraduate medical education. However, the impact of curricular course structure on student outcome needs to be determined. This study assessed changes in fourth-year medical students' evaluations of clinical teaching sessions before and after the introduction of a new course format. The curricular structure of bedside teaching sessions in cardiology was modified without changing the amount of teaching time. Clinical teachers were instructed about the new teaching format and learning objectives. The new format implemented for adult but not paediatric cardiology sessions was piloted with 143 students in winter 2007/08. By computing effect sizes, evaluation results were compared to data obtained from 185 students before the intervention. Significant rating increases were observed for adult cardiology teaching sessions (Cohen's d = 0.66) but not paediatric cardiology sessions (d = 0.22). In addition to improving the structure and organization of the course, the intervention significantly impacted on students' perceptions of their learning outcome regarding practical skills (d = 0.69). Minimal curricular changes combined with basic faculty development measures significantly increase students' perception of learning outcome. Curricular structure needs to be considered when planning bedside teaching sessions in medical undergraduate training.

  14. 75 FR 73136 - Sunshine Act Notice

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-29

    .... Place: Commissioners' Conference Room, 11555 Rockville Pike, Rockville, Maryland. Status: Public and.... Affirmation Session (Public Meeting) (Tentative). a. Tennessee Valley Authority (Watts Bar Nuclear Plant, Unit 2), Southern Alliance for Clean Energy's Petition for Interlocutory Review of LBP-10-12 (Denying...

  15. Shipment of spent nuclear fuel from U.S. Navy ships and submarines to the Idaho National Engineering Laboratory (INEL). Hearing before the Subcommittee on Nuclear Deterrence, Arms Control and Defense Intelligence of the Committee on Armed Services, United States Senate, One Hundred Third Congress, First Session, July 28, 1993

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1994-12-31

    The purpose of the hearing was to review the impact of the U.S. District Court of Idaho ruling prohibiting receipt of spent nuclear fuel by the Department of Energy (DOE). The court`s ruling enjoined the DOE from receiving spent nuclear fuel, including nuclear fuel from naval surface ships and submarines, at the Idaho National Engineering Laboratory until such time as the DOE completes an environmental impact statement on the transportation, shipment, processing, and storage of spent fuel. Statements of government officials are included. The text of the Court ruling is also included.

  16. Aeropropulsion 1987. Session 2: Aeropropulsion Structures Research

    NASA Technical Reports Server (NTRS)

    1987-01-01

    Aeropropulsion systems present unique problems to the structural engineer. The extremes in operating temperatures, rotational effects, and behaviors of advanced material systems combine into complexities that require advances in many scientific disciplines involved in structural analysis and design procedures. This session provides an overview of the complexities of aeropropulsion structures and the theoretical, computational, and experimental research conducted to achieve the needed advances.

  17. Radiation: Physical Characterization and Environmental Measurements

    NASA Technical Reports Server (NTRS)

    1997-01-01

    In this session, Session WP4, the discussion focuses on the following topics: Production of Neutrons from Interactions of GCR-Like Particles; Solar Particle Event Dose Distributions, Parameterization of Dose-Time Profiles; Assessment of Nuclear Events in the Body Produced by Neutrons and High-Energy Charged Particles; Ground-Based Simulations of Cosmic Ray Heavy Ion Interactions in Spacecraft and Planetary Habitat Shielding Materials; Radiation Measurements in Space Missions; Radiation Measurements in Civil Aircraft; Analysis of the Pre-Flight and Post-Flight Calibration Procedures Performed on the Liulin Space Radiation Dosimeter; and Radiation Environment Monitoring for Astronauts.

  18. Summary of long-baseline systematics session at CETUP*2014

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cherdack, Daniel; Worcester, Elizabeth

    2015-10-15

    A session studying systematics in long-baseline neutrino oscillation physics was held July 14-18, 2014 as part of CETUP* 2014. Systematic effects from flux normalization and modeling, modeling of cross sections and nuclear interactions, and far detector effects were addressed. Experts presented the capabilities of existing and planned tools. A program of study to determine estimates of and requirements for the size of these effects was designed. This document summarizes the results of the CETUP* systematics workshop and the current status of systematic uncertainty studies in long-baseline neutrino oscillation measurements.

  19. Operational Aspects of Space Radiation

    NASA Technical Reports Server (NTRS)

    1997-01-01

    In this session, Session FA4, the discussion focuses on the following topics: Solar Particle Events and the International Space Station; Radiation Environment on Mir and ISS Orbits During the Solar Cycle; New approach to Radiation Risk Assessment; An Industrial Method to Predict Major Solar Flares for a Better Protection of Human Beings in Space; Description of the Space Radiation Control System for the Russian Segment of ISS; Orbit Selection and Its Impact on Radiation Warning Architecture for a Human Mission to Mars; and Space Nuclear Power - Technology, Policy and Risk Considerations in Human Missions to Mars.

  20. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moyer, Bruce A.

    The North American industry has employed major solvent-extraction processes to support a wide range of separations including but not limited to chemical, metallurgical, nuclear, biochemical, pharmaceutical, and petroleum applications. The knowledge enabling these separations has been obtained through fundamental studies in academe, government and industry. The International Solvent Extraction Conferences have been and continue to be a major gathering of scientists, engineers, operators, and vendors from around the world, who present new findings since the last meeting, exchange ideas, make business contacts, and conduct collegial discussions. The ISEC 2008 program emphasizes fundamentals to industrial applications of solvent extraction, particularly howmore » this broad spectrum of activities is interconnected and has led to the implementation of novel processes. The oral and poster sessions have been organized into seven topics: Fundamentals; Novel Reagents, Materials and Techniques; Nuclear Fuel Reprocessing; Hydrometallurgy and Metals Extraction; Analytical and Preparative Applications; Biotechnology, Pharmaceuticals, Life-Science Products, and Organic Products; and Process Chemistry and Engineering. Over 350 abstracts were received, resulting in more than 260 manuscripts published in these proceedings. Five outstanding plenary presentations have been identified, with five parallel sessions for oral presentations and posters. In recognition of the major role solvent extraction (SX) plays in the hydrometallurgical and nuclear industries, these proceedings begin with sections focusing on hydrometallurgy, process chemistry, and engineering. More fundamental topics follow, including sections on novel reagents, materials, and techniques, featuring novel applications in analytical and biotechnology areas. Despite the diversity of topics and ideas represented, however, the primary focus of the ISEC community continues to be metals extraction. Four papers from these proceedings have been entered already in INIS in the form of individual reports. Among the remaining papers, 60 have been selected from the following sessions: Plenary Lectures, Hydrometallurgy and Metals Extraction, Nuclear Fuel Reprocessing, Analytical and Preparative Applications, Fundamentals, and Novel Reagents, Materials, and Techniques.« less

  1. Women and Men of the Manhattan Project

    NASA Astrophysics Data System (ADS)

    Marshall, Jill; Herzenberg, Caroline; Howes, Ruth; Weaver, Ellen; Gans, Dorothy

    2010-04-01

    In the early 1990s Ruth Howes, a nuclear physicist on the faculty at Ball State University, and Caroline Herzenberg, a nuclear physicist at Argonne National Laboratory, were asked to write a chapter on the Manhattan Project for a volume on women working on weapons development for the military. Realizing that they knew very little about the women who had been involved in that effort, they embarked on a mission to find out more. Howes and Herzenberg were able to document the wartime contributions of more than 1000 women in Their Day in the Sun,2 preserving this legacy for generations to come. At the 2009 AAPT Winter Meeting in Chicago, the AAPT Committee on Women in Physics celebrated the accomplishments of these women and the men who worked beside them in a session co-sponsored with the History and Philosophy of Physics and the Concerns of Senior Physicists committees. Howes presented an overview of the contributions of women to the development of the first nuclear weapon, and the session was honored with the presence of Manhattan Project veterans Ellen Cleminshaw Weaver, who worked at Oak Ridge, and Dorothy Marcus Gans, who worked as a technician in the Metallurgical Laboratory in Chicago.

  2. Research in Structures, Structural Dynamics and Materials, 1990

    NASA Technical Reports Server (NTRS)

    Barthelemy, Jean-Francois M. (Compiler); Noor, Ahmed K. (Compiler)

    1990-01-01

    The Structural Dynamics and Materials (SDM) Conference was held on April 2 to 4, 1990 in Long Beach, California. This publication is a compilation of presentations of the work-in-progress sessions and does not contain papers from the regular sessions since those papers are published by AIAA in the conference proceedings.

  3. TH-AB-206-00: Challenges and Opportunities for Nuclear Medicine Theranostics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    In the past few decades, the field of nuclear medicine has made long strides with the continued advancement of related sciences and engineering and the availability of diagnostic and therapeutic radionuclides. Leveraging these advancements while combining the advantages of therapeutic and diagnostic radionuclides into one radiopharmaceutical has also created a new subfield “theranostics” in nuclear medicine that has the potential to further propel the field into the future. This session is composed of two talks; one focused on the physics principles of theranostics from properties of beta and alpha emitting radionuclides to dosimetric models and quantification; while the second describesmore » preclinical and clinical applications of theranostics and discusses the challenges and opportunities of bringing them to the clinic. At the end of the session the listener should be able to identify: The different properties of beta and alpha emitting radionuclides Which radionuclides are selected for which nuclear medicine therapies and why How PET can be used to accurately quantify the uptake of tumor targeting molecules How individualized dosimetry can be performed from the management of thyroid cancer to novel radiolabeled antibody therapies Promising pre-clinical radiopharmaceutical pairs in prostate cancer and melanoma. Promising clinical Theranostics in neuroendocrine cancers. Challenges of bringing Theranostics to the clinic. E. Delpassand, RITA Foundation -Houston; SBIR Grant; CEO and share holder of RadioMedix.« less

  4. TH-AB-206-02: Nuclear Medicine Theronostics: Wave of the Future; Pre-Clinical and Clinical Opportunities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Delpassand, E.

    In the past few decades, the field of nuclear medicine has made long strides with the continued advancement of related sciences and engineering and the availability of diagnostic and therapeutic radionuclides. Leveraging these advancements while combining the advantages of therapeutic and diagnostic radionuclides into one radiopharmaceutical has also created a new subfield “theranostics” in nuclear medicine that has the potential to further propel the field into the future. This session is composed of two talks; one focused on the physics principles of theranostics from properties of beta and alpha emitting radionuclides to dosimetric models and quantification; while the second describesmore » preclinical and clinical applications of theranostics and discusses the challenges and opportunities of bringing them to the clinic. At the end of the session the listener should be able to identify: The different properties of beta and alpha emitting radionuclides Which radionuclides are selected for which nuclear medicine therapies and why How PET can be used to accurately quantify the uptake of tumor targeting molecules How individualized dosimetry can be performed from the management of thyroid cancer to novel radiolabeled antibody therapies Promising pre-clinical radiopharmaceutical pairs in prostate cancer and melanoma. Promising clinical Theranostics in neuroendocrine cancers. Challenges of bringing Theranostics to the clinic. E. Delpassand, RITA Foundation -Houston; SBIR Grant; CEO and share holder of RadioMedix.« less

  5. Nineteenth annual actinide separations conference: Conference program and abstracts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bronson, M.

    This report contains the abstracts from the conference presentations. Sessions were divided into the following topics: Waste treatment; Spent fuel treatment; Issues and responses to Defense Nuclear Facility Safety Board 94-1; Pyrochemical technologies; Disposition technologies; and Aqueous separation technologies.

  6. 78 FR 27419 - Final Safety Culture Policy Statement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-05-10

    .... The BSEE appreciates this suggestion and is currently working to develop information sessions and... industries (e.g., Federal Aviation Administration, Nuclear Regulatory Commission, Petroleum Safety Authority... environmental stewardship to a vigorous and respected offshore energy industry. Each and every person involved...

  7. MEVTV Workshop on Tectonic Features on Mars

    NASA Technical Reports Server (NTRS)

    Watters, Thomas R. (Editor); Golombek, Matthew P. (Editor)

    1989-01-01

    The state of knowledge of tectonic features on Mars was determined and kinematic and mechanical models were assessed for their origin. Three sessions were held: wrinkle ridges and compressional structure; strike-slip faults; and extensional structures. Each session began with an overview of the features under discussion. In the case of wrinkle ridges and extensional structures, the overview was followed by keynote addresses by specialists working on similar structures on the Earth. The first session of the workshop focused on the controversy over the relative importance of folding, faulting, and intrusive volcanism in the origin of wrinkle ridges. The session ended with discussions of the origin of compressional flank structures associated with Martian volcanoes and the relationship between the volcanic complexes and the inferred regional stress field. The second day of the workshop began with the presentation and discussion of evidence for strike-slip faults on Mars at various scales. In the last session, the discussion of extensional structures ranged from the origin of grabens, tension cracks, and pit-crater chains to the origin of Valles Marineris canyons. Shear and tensile modes of brittle failure in the formation of extensional features and the role of these failure modes in the formation of pit-crater chains and the canyons of Valles Marineris were debated. The relationship of extensional features to other surface processes, such as carbonate dissolution (karst) were also discussed.

  8. Demographic, Physiologic, and Psychosocial Correlates of Physical Activity in Structured Exercise and Sports Among Low-Income, Overweight Children.

    PubMed

    Hatfield, Daniel P; Chomitz, Virginia R; Chui, Kenneth K H; Sacheck, Jennifer M; Economos, Christina D

    2015-01-01

    To describe correlates of physical activity (PA) in structured exercise and structured sports sessions among low-income, overweight children participating in a community-based PA program. A total of 93 children (55% male; 91% Hispanic) aged 8-14 years were included. Participants wore pedometers in a sample of 10 of 59 total sessions offered; mean steps per minute were calculated for structured exercise and sports sessions. Separate multivariable regression models tested associations between steps per minute in exercise and sports sessions and 5 potential correlates: baseline body mass index z-score, aerobic fitness (Progressive Aerobic Cardiorespiratory Endurance Run laps), perceived athletic competence (Harter self-perception profile), sex, and age. Only age (ß = -2.9; P = .02) significantly predicted steps per minute in exercise sessions. Age (ß = -4.3; P = .007), fitness (ß = 0.45; P = .03), and male sex (ß = 8.7; P = .02) significantly predicted steps per minute in sports. In structured exercise and sports, perceived competence may not influence overweight and obese children's PA. However, girls and older or less fit children may engage less actively, especially in sports. Copyright © 2015 Society for Nutrition Education and Behavior. Published by Elsevier Inc. All rights reserved.

  9. The experience of sessional teachers in nursing: A qualitative study.

    PubMed

    Dixon, Kathleen A; Cotton, Antoinette; Moroney, Robyn; Salamonson, Yenna

    2015-11-01

    Worldwide, there is a growing reliance on sessional teachers in universities. This trend is reflected in an undergraduate nursing program in a large Australian metropolitan university where a significant proportion of contact hours is staffed by sessional teachers, yet little is known about what type of support is needed for sessional teachers to optimise their capacity to contribute to the academic program. To describe the experiences of sessional teachers in a Bachelor of Nursing program in an Australian university. This is an exploratory qualitative study; fifteen sessional teachers were interviewed using semi-structured questions to explore their experiences of teaching. This study was conducted in a large metropolitan school of nursing located on three sites. A purposive sample of 15 sessional teachers was interviewed for this study. Semi-structured interviews were conducted face to face. Thematic analysis was used to identify major themes in the interview data and collaborative analysis was undertaken to ensure rigour. Findings revealed that sessional teachers enjoyed teaching, were committed to their role and viewed their clinical currency as a valuable asset for teaching. However, participants also spoke about wanting a sense of belonging to the School, with most feeling they were "outsiders". Areas identified for improvement included system and process issues, micro teaching and assessment skills, classroom management and timely access to resources. There is a need to improve sessional teachers' sense of belonging and to provide an inclusive structure and culture to optimise their capacity to contribute to the academic program. Copyright © 2015 Elsevier Ltd. All rights reserved.

  10. Different Strokes for Different Folks: Jung's Typology and Structured Experiences.

    ERIC Educational Resources Information Center

    Haber, Russell Alan

    1980-01-01

    Examined and compared the evaluations of students differentiated by Carl Jung's psychotypology when they were involved in either a session of nonverbal communication experiences or a session of fantasy experiences. Some of the Jungian psychological types preferred different structured experiences. (Author)

  11. The American College of nuclear physicians 18th annual meeting and scientific sessions DOE day: Substance abuse and nuclear medicine abstracts

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1992-02-01

    Despite the enormous personal and social cost Of substance abuse, there is very little knowledge with respect to the mechanisms by which these drugs produce addiction as well as to the mechanisms of toxicity. Similarly, there is a lack of effective therapeutic intervention to treat the drug abusers. In this respect, nuclear medicine could contribute significantly by helping to gather information using brain imaging techniques about mechanisms of drug addiction which, in turn, could help design better therapeutic interventions, and by helping in the evaluation and diagnosis of organ toxicity from the use of drugs of abuse. This volume containsmore » six short descriptions of presentations made at the 18th Meeting of the American College of Nuclear Physicians -- DOE Day: Substance Abuse and Nuclear Medicine.« less

  12. 75 FR 32230 - Meetings; Sunshine Act

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-07

    .... Place: Commissioners' Conference Room, 11555 Rockville Pike, Rockville, Maryland. Status: Public and closed. Additional Items To Be Considered: Wednesday, June 9, 2010 1:25 p.m. Affirmation Session (Public Meeting) (Tentative). a. Review of Final Rule Package, Export and Import of Nuclear Equipment and Material...

  13. EPRI steam turbine and generator NDE, life assessment, and maintenance workshop. [Electric Power Research Institute (EPRI), NonDestructive Evaluation (NDE)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nottingham, L.D.; Sabourin, P.F.

    1992-10-01

    On July 16--19, 1991, the EPRI NDE Center hosted the second EPRI Steam Turbine and Generator NDE, Life Assessment and Maintenance Workshop. This workshop was co-sponsored by the Nuclear Power and the Generation and Storage Divisions of EPRI. Attendees represented all sectors of the industry including utilities, equipment manufacturers, forging suppliers, service organizations, government organizations, insurancecarriers, and consultants from the United States and abroad. Domestic utility presence was again strong, with 105 representatives from 44 utilities in attendance. Australia, Canada, England, Finland, France, Germany, Italy, Japan, Korea, New Zealand, Spain, Sweden and Switzerland were represented in the international contingent. Amore » key and integral part of the workshop was a vendor equipment fair, in which some 23 organizations displayed and demonstrated equipment and services that they offer. Formal presentation of 53 technical papers made up the technical portion of the agenda, which also included two breakout discussion sessions on topical subjects. To provide optimum opportunity for participants to hear all presentations on closely related topics, the sessions were set such that a NDE session ran parallel to the life assessment session. The first NDE session included turbine related topics while the first life assessment session addressed generator issues. The last sessions of the workshop were just reversed with turbine topics being addressed in the life assessment session while generator issues were presented in the NDE session. Presentations on maintenance topics and on monitoring and diagnostics topics were also presented in parallel sessions. These proceedings contain the texts of the papers presented at the workshop. Individual papers in indexed separately.« less

  14. A Literature Review and Compilation of Nuclear Waste Management System Attributes for Use in Multi-Objective System Evaluations.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kalinina, Elena Arkadievna; Samsa, Michael

    The purpose of this work was to compile a comprehensive initial set of potential nuclear waste management system attributes. This initial set of attributes is intended to serve as a starting point for additional consideration by system analysts and planners to facilitate the development of a waste management system multi-objective evaluation framework based on the principles and methodology of multi-attribute utility analysis. The compilation is primarily based on a review of reports issued by the Canadian Nuclear Waste Management Organization (NWMO) and the Blue Ribbon Commission on America's Nuclear Future (BRC), but also an extensive review of the available literaturemore » for similar and past efforts as well. Numerous system attributes found in different sources were combined into a single objectives-oriented hierarchical structure. This study provides a discussion of the data sources and the descriptions of the hierarchical structure. A particular focus of this study was on collecting and compiling inputs from past studies that involved the participation of various external stakeholders. However, while the important role of stakeholder input in a country's waste management decision process is recognized in the referenced sources, there are only a limited number of in-depth studies of the stakeholders' differing perspectives. Compiling a comprehensive hierarchical listing of attributes is a complex task since stakeholders have multiple and often conflicting interests. The BRC worked for two years (January 2010 to January 2012) to "ensure it has heard from as many points of view as possible." The Canadian NWMO study took four years and ample resources, involving national and regional stakeholders' dialogs, internet-based dialogs, information and discussion sessions, open houses, workshops, round tables, public attitude research, website, and topic reports. The current compilation effort benefited from the distillation of these many varied inputs conducted by the previous studies.« less

  15. PREFACE: New nuclear structure phenomena in the vicinity of closed shells

    NASA Astrophysics Data System (ADS)

    Johnson, A.; Wyss, R.

    1995-01-01

    The proceedings of the international symposium on "New Nuclear Structure Phenomena in the Vicinity of Closed Shells - SELMA 94", held in Stockholm, Uppsala and on the Baltic Sea from Aug. 30 - Sep. 3 are collected in this volume. Since almost 40% of the session time was kept open for discussions, it is difficult to give full justice to the character of the meeting in a written report. However, since also many posters are presented in this volume, we hope that some of the flavour of this lively symposium will pass onto the reader. We have chosen to group related contributions in order to facilitate the reading. Several articles, though, may fit into several categories. With the event of large detector arrays there has been a tremendous development in the field of nuclear spectroscopy. The discovery of super-deformation has been followed by detailed spectroscopy in the second well. Hence, the concept of shell closure is reinterpreted in general terms, involving shapes different from spherical. Close to the drip lines, we expect new shells and new structure effects to emerge. Loosely bound neutrons may form a new state of nuclear matter. The regions of the nuclear chart far from the line of stability can be explored in the future by means of radioactive ion beams. New structure effects, that one might encounter far from the line of stability was one of the themes of this conference. The strong impact of the nuclear shell model is also evident in other branches of physics, like the structure of metal-clusters. Special attention was paid to the Sn-isotopes. In the Sn-isotopic chain, spectroscopic measurements are extending beyond the doubly-magic nucleus 132Sn. Large efforts have recently been made to study nuclei in the vicinity of the doubly-magic nucleus 100Sn, the other extreme end of the chain. Spectroscopic data on 100Sn would open the entire shell for nuclear structure studies, ranging over a number of 32 neutrons. During the organization of this meeting, the first 100Sn nuclei were observed at GSI, Germany, and in a subsequent experiment at GANIL, France. Results from these experiments were reported during the symposium as were much of the recent data around "classical" shell model nuclei. Neutron deficient nuclei in the Sn region show a variety of phenomena, such as coexisting shapes, enhanced quadrupole transitions etc. The role of intruder states in this mass region as well as the excitation pattern is still a puzzle for experimentalists and theoreticians and was discussed during the meeting. More work is needed until a unified picture of the structure of these nuclei will emerge. The combination of powerful mean-field models, large scale shell model calculations as well as new algebraic approaches to nuclear structure shows the strong and lively development in the field of nuclear theory as was evident from the presentations. It is obvious that great effort is needed to match the rapid development in the field of experimental nuclear structure. The organizing committee expresses special thanks to the Royal Swedish Academy of Sciences, through its Nobel Institute for Physics, for its generous support. We also want to thank the Royal Institute of Technology and Uppsala University for supporting this symposium. All this support was extremely essential for organizing the meeting as well as for rendering it success. We are very pleased about the possibility to print the proceedings of this meeting in Physics Scripta and thank their staff for helpful collaboration. Thanks also to the international advisory committee for its helpful work to select speakers and for suggestions. Conference secretary Inger Ericson's assistance during the meeting as well as the work of the organizing committee is highly appreciated. Finally, we like to thank all speakers and participants for making this symposium extremely lively and exciting. Last but not least: this symposium got its name from little Selma, born 19 January 1994, daughter of A Atac and J Nyberg.

  16. 16th International Conference on Nuclear Structure: NS2016

    DOE PAGES

    Galindo-Uribarri, Alfredo

    2016-10-28

    Every two years the Nuclear Structure (NS) conference series brings together researchers from an international community of experimental and theoretical nuclear physicists to present and discuss their latest results in nuclear structure. This biennial conference covered the latest results on experimental and theoretical research into the structure of nuclei at the extremes of isospin, excitation energy, mass, and angular momentum. Topics included many of the most exciting areas of modern nuclear structure research such as transitional behavior, nuclear structure and its evolution across the nuclear landscape, shell structure, collectivity, nuclear structure with radioactive beams, and macroscopic and microscopic approaches tomore » nuclear structure.« less

  17. 16th International Conference on Nuclear Structure: NS2016

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Galindo-Uribarri, Alfredo

    Every two years the Nuclear Structure (NS) conference series brings together researchers from an international community of experimental and theoretical nuclear physicists to present and discuss their latest results in nuclear structure. This biennial conference covered the latest results on experimental and theoretical research into the structure of nuclei at the extremes of isospin, excitation energy, mass, and angular momentum. Topics included many of the most exciting areas of modern nuclear structure research such as transitional behavior, nuclear structure and its evolution across the nuclear landscape, shell structure, collectivity, nuclear structure with radioactive beams, and macroscopic and microscopic approaches tomore » nuclear structure.« less

  18. High energy interactions of cosmic ray particles

    NASA Technical Reports Server (NTRS)

    Jones, L. W.

    1986-01-01

    The highlights of seven sessions of the Conference dealing with high energy interactions of cosmic rays are discussed. High energy cross section measurements; particle production-models of experiments; nuclei and nuclear matter; nucleus-nucleus collision; searches for magnetic monopoles; and studies of nucleon decay are covered.

  19. The Effect of Postmastectomy Radiation Therapy on Breast Implants: Material Analysis on Silicone and Polyurethane Prosthesis.

    PubMed

    Lo Torto, Federico; Relucenti, Michela; Familiari, Giuseppe; Vaia, Nicola; Casella, Donato; Matassa, Roberto; Miglietta, Selenia; Marinozzi, Franco; Bini, Fabiano; Fratoddi, Ilaria; Sciubba, Fabio; Cassese, Raffaele; Tombolini, Vincenzo; Ribuffo, Diego

    2018-05-17

    The pathogenic mechanism underlying capsular contracture is still unknown. It is certainly a multifactorial process, resulting from human body reaction, biofilm activation, bacteremic seeding, or silicone exposure. The scope of the present article is to investigate the effect of hypofractionated radiotherapy protocol (2.66 Gy × 16 sessions) both on silicone and polyurethane breast implants. Silicone implants and polyurethane underwent irradiation according to a hypofractionated radiotherapy protocol for the treatment of breast cancer. After irradiation implant shells underwent mechanical, chemical, and microstructural evaluation by means of tensile testing, infrared spectra in attenuated total reflectance mode, nuclear magnetic resonance, and field emission scanning electron microscopy. At superficial analysis, irradiated silicone samples show several visible secondary and tertiary blebs. Polyurethane implants showed an open cell structure, which closely resembles a sponge. Morphological observation of struts from treated polyurethane sample shows a more compact structure, with significantly shorter and thicker struts compared with untreated sample. The infrared spectra in attenuated total reflectance mode spectra of irradiated and control samples were compared either for silicon and polyurethane samples. In the case of silicone-based membranes, treated and control specimens showed similar bands, with little differences in the treated one. Nuclear magnetic resonance spectra on the fraction soluble in CDCl3 support these observations. Tensile tests on silicone samples showed a softer behavior of the treated ones. Tensile tests on Polyurethane samples showed no significant differences. Polyurethane implants seem to be more resistant to radiotherapy damage, whereas silicone prosthesis showed more structural, mechanical, and chemical modifications.

  20. Transactions of the Twenty-First Water Reactor Safety Information Meeting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Monteleone, S.

    1993-10-01

    This report contains summaries of papers on reactor safety research to be presented at the 21st Water Reactor Safety Information Meeting at the Bethesda Marriott Hotel, Bethesda, Maryland, October 25--27, 1993. The summaries briefly describe the programs and results of nuclear safety research sponsored by the Office of Nuclear Regulatory Research, US NRC. Summaries of invited papers concerning nuclear safety issues from US government laboratories, the electric utilities, the Electric Power Research Institute (EPRI), the nuclear industry, and from foreign governments and industry are also included. The summaries have been compiled in one report to provide a basis for meaningfulmore » discussion and information exchange during the course of the meeting and are given in the order of their presentation in each session.« less

  1. The 1991 International Conference on Aging Aircraft and Structural Airworthiness

    NASA Technical Reports Server (NTRS)

    Harris, Charles E. (Editor)

    1992-01-01

    Technical sessions of the conference included structural performance, nondestructive evaluation, maintenance and repair, international activities, and commuter airlines. Each session was organized to provide a well-rounded view of the subject from the industry, regulatory, and research perspective. Thirty-four presentations were given by the international technical community.

  2. Proceedings of the 7th International Meeting on Nuclear Reactor Thermal-Hydraulics NURETH-7. Volume 3, Sessions 12-16

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Block, R.C.; Feiner, F.

    This document, Volume 3, includes papers presented at the 7th International Meeting on Nuclear Reactor Thermal-Hydraulics (NURETH-7) September 10--15, 1995 at Saratoga Springs, N.Y. The following subjects are discussed: Progress in analytical and experimental work on the fundamentals of nuclear thermal-hydraulics, the development of advanced mathematical and numerical methods, ad the application of advancements in the field in the development of novel reactor concepts. Also combined issues of thermal-hydraulics and reactor/power-plant safety, core neutronics and/or radiation. Selected abstracts have been indexed separately for inclusion in the Energy Science and Technology Database.

  3. Feeling Good about Me.

    ERIC Educational Resources Information Center

    Morrison, Kenneth; Thompson, Marcia

    This document contains 18 structured learning sessions featuring fables, nursery rhymes and directed day dreams to help elementary school students become aware of themselves and their feelings. Each session is a self-contained unit, so the sessions may be used separately or as a developmental sequence. The primary goals of the book are to help…

  4. Few-Nucleon Research at TUNL: Probing Two- and Three-Nucleon Interactions with Neutrons

    NASA Astrophysics Data System (ADS)

    Howell, C. R.; Tornow, W.; Witała, H.

    2016-03-01

    The central goal of few-nucleon research at the Triangle Universities Nuclear Laboratory (TUNL) is to perform measurements that contribute to advancing ab-initio calculations of nuclear structure and reactions. The program aims include evaluating theoretical treatments of few-nucleon reaction dynamics through strategically comparing theory predictions to data, determining properties of the neutron-neutron interaction that are not accessible in two-nucleon reactions, and searching for evidence of longrange features of three-nucleon interactions, e.g., spin and isospin dependence. This paper will review studies of three- and four-nucleon systems at TUNL conducted using unpolarized and polarized neutron beams. Measurements of neutron-induced reactions performed by groups at TUNL over the last six years are described in comparison with theory predictions. The results are discussed in the context of the program goals stated above. Measurements of vector analyzing powers for elastic scattering in A=3 and A=4 systems, differential cross sections for neutron-deuteron elastic scattering and neutrondeuteron breakup in several final-state configurations are described. The findings from these studies and plans for the coming three years are presented in the context of worldwide activities in this front, in particular, research presented in this session.

  5. American College of Nuclear Physics 1991 DOE day symposium: Aids and nuclear medicine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1991-12-31

    Since first described in 1981, the acquired immunodeficiency syndrome (AIDS) has become the medical dilemma of the century. AIDS retrovirus, and the economic consequences of this exposure are staggering. AIDS has been the topic of conferences and symposia worldwide. This symposium, to be held on January 25, 1991, at the 17th Annual Meeting and Scientific Sessions of the American College of Nuclear Physicians, will expose the Nuclear Medicine Physicians/Radiologists to their role in the diagnosis of AIDS, and will educate them on the socio-economic and ethical issues related to this problem. In addition, the Nuclear Medicine Physicians/Radiologists must be awaremore » of their role in the management of their departments in order to adequately protect the health care professionals working in their laboratories. Strategies are currently being developed to control the spread of bloodborne diseases within the health care setting, and it is incumbent upon the Nuclear Medicine community to be aware of such strategies.« less

  6. The 1993 Utah Legislative Session: Policy Implications for Educational Structure and Governance.

    ERIC Educational Resources Information Center

    Johnson, Bob L., Jr.; Sperry, David J.

    This paper presents an overview and description of "significant" education legislation passed during the 1993 Utah Legislative Session. Specific attention is given to legislation that affects the governance and structure of education in the state. The centerpiece of the Governor's educational agenda and the definitive action of the 1993…

  7. PREFACE: 11th International Conference on Nucleus-Nucleus Collisions (NN2012)

    NASA Astrophysics Data System (ADS)

    Li, Bao-An; Natowitz, Joseph B.

    2013-03-01

    The 11th International Conference on Nucleus-Nucleus Collisions (NN2012) was held from 27 May to 1 June 2012, in San Antonio, Texas, USA. It was jointly organized and hosted by The Cyclotron Institute at Texas A&M University, College Station and The Department of Physics and Astronomy at Texas A&M University-Commerce. Among the approximately 300 participants were a large number of graduate students and post-doctoral fellows. The Keynote Talk of the conference, 'The State of Affairs of Present and Future Nucleus-Nucleus Collision Science', was given by Dr Robert Tribble, University Distinguished Professor and Director of the TAMU Cyclotron Institute. During the conference a very well-received public lecture on neutrino astronomy, 'The ICEcube project', was given by Dr Francis Halzen, Hilldale and Gregory Breit Distinguished Professor at the University of Wisconsin, Madison. The Scientific program continued in the general spirit and intention of this conference series. As is typical of this conference a broad range of topics including fundamental areas of nuclear dynamics, structure, and applications were addressed in 42 plenary session talks, 150 parallel session talks, and 21 posters. The high quality of the work presented emphasized the vitality and relevance of the subject matter of this conference. Following the tradition, the NN2012 International Advisory Committee selected the host and site of the next conference in this series. The 12th International Conference on Nucleus-Nucleus Collisions (NN2015) will be held 21-26 June 2015 in Catania, Italy. It will be hosted by The INFN, Laboratori Nazionali del Sud, INFN, Catania and the Dipartimento di Fisica e Astronomia of the University of Catania. The NN2012 Proceedings contains the conference program and 165 articles organized into the following 10 sections 1. Heavy and Superheavy Elements 2. QCD and Hadron Physics 3. Relativistic Heavy-Ion Collisions 4. Nuclear Structure 5. Nuclear Energy and Applications of Nuclear Science and Technologies 6. Nuclear Reactions and Structure of Unstable Nuclei 7. Equation of State of Neutron-Rich Nuclear Matter, Clusters in Nuclei and Nuclear Reactions 8. Fusion and Fission 9. Nuclear Astrophysics 10. New Facilities and Detectors We would like to thank Texas A&M University and Texas A&M University-Commerce for their organizational support and for providing financial support for many students and postdocs and those who had special need. This support helped assure the success of NN2012. Special thanks also go to all members of the International Advisory Committee and the Local Organizing Committee (listed below) for their great work in advising upon, preparing and executing the NN2012 scientific program as well as the social events that all together made the NN2012 an enjoyable experience for both the participants and their companions. NN2012 International Advisory Committee N Auerbach (Israel) J Aysto (Finland) C Beck (France) S Cherubini (Italy) L Ferreira (Portugal) C Gagliardi (USA) S Gales (France) C Gale (Canada) W Gelletly (Great Britain) Paulo R S Gomes (Brazil) W Greiner (Germany) W Henning (USA) D Hinde (Australia) S Hofmann (Germany) M Hussein (Brazil) B Jacak (USA) S Kailas (India) W G Lynch (USA) Z Majka (Poland) L McLerran (USA) V Metag (Germany) K Morita (Japan) B Mueller (USA) D G Mueller (France) T Motobayashi (Japan) W Nazarewicz (USA) Y Oganessian (Russia) J Nolen (USA) E K Rehm (USA) N Rowley (France) B Sherrill (USA) J Schukraft (Switzerland) W Q Shen (China) A Stefanini (Italy) H Stoecker (Germany) A Szanto de Toledo (Brazil) U van Kolck (USA) W von Oertzen (Germany) M Wiescher (USA) N Xu (USA) N V Zamfir (Romania) W L Zhan (China) H Q Zhang (China) NN2012 Local Organizing Committee Marina Barbui Carlos Bertulani Robert Burch Jr Cheri Davis Cody Folden Kris Hagel John Hardy Bao-An Li (Co-Chair and Scientific Secretary) Joseph Natowitz (Co-Chair) Ralf Rapp Livius Trache Sherry Yennello Editors of NN2012 Proceedings Bao-An Li (Texas A&M University-Commerce) and Joseph Natowitz (Texas A&M University) 7 January 2013, Texas, USA

  8. Proceedings of the Nuclear Criticality Technology Safety Workshop

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rene G. Sanchez

    1998-04-01

    This document contains summaries of most of the papers presented at the 1995 Nuclear Criticality Technology Safety Project (NCTSP) meeting, which was held May 16 and 17 at San Diego, Ca. The meeting was broken up into seven sessions, which covered the following topics: (1) Criticality Safety of Project Sapphire; (2) Relevant Experiments For Criticality Safety; (3) Interactions with the Former Soviet Union; (4) Misapplications and Limitations of Monte Carlo Methods Directed Toward Criticality Safety Analyses; (5) Monte Carlo Vulnerabilities of Execution and Interpretation; (6) Monte Carlo Vulnerabilities of Representation; and (7) Benchmark Comparisons.

  9. 76 FR 34773 - Final Safety Culture Policy Statement

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-14

    ... Special Joint Session on Safety Culture at the Health Physics Society Annual Meeting, and presentations on... safety-first focus in nuclear work environments for public health and safety. The Commission's emphasis... operations, if attacked, could have an impact on public health and safety. During the early years of...

  10. Nuclear Security: Target Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Singh, Surinder Paul; Gibbs, Philip W.; Bultz, Garl A.

    2014-03-01

    This objectives of this session were to understand the basic steps of target identification; describe the SNRI targets in detail; characterize specific targets with more detail; prioritize targets based on guidance documents; understand the graded safeguards concept; identify roll up and understand why it is a concern; and recognize the category for different materials.

  11. Case Studies from Russia, a Session of a NATO Conference on Defense Conversion.

    DTIC Science & Technology

    1996-10-29

    84101 USA Oleg Diyankov Russian Federal Nuclear Center Donald Hislop P.O. Box 245 Shezhinsk Department of Sociology, University of Chelyabinsk Region...database on the major aggregates related to European defense activity including statistics from 1980 to 1993 on defense budget, equipment purchases, R/D

  12. English/Japanese Professional Interpretation: Its Linguistic and Conceptual Problems.

    ERIC Educational Resources Information Center

    Ishikawa, Luli

    1995-01-01

    A study of simultaneous interpretation from Japanese to English focused on problems inherent in simultaneous language processing. Data were drawn from a discussion session at an international conference of physicians concerning nuclear war. Transcription of the Japanese source text (romanized), English product, and a gloss of lexical equivalents…

  13. A Model for the Redesign of Training Materials for the Nuclear Power Industry.

    ERIC Educational Resources Information Center

    Gredler, Margaret Bell

    1986-01-01

    Presents consultant/staff model for training program redesign and discusses activities involved: interpretation of Instructional System Design (ISD) model concepts into plans in trainer's content area and sequenced sets of content-appropriate verbs for objectives; presenting training sessions on design issues; and holding individual conference…

  14. ASP Networking Sessions Summary

    NASA Astrophysics Data System (ADS)

    Bartolone, L. M.

    2008-06-01

    In response to evaluation conducted during the Annual Meeting of the Astronomical Society of the Pacific in 2006, ``Engaging the EPO Community: Best Practices, New Approaches,'' loosely structured networking sessions were added by the program committee in an effort to assist conference attendees in achieving their stated conference goals. The co-chairs of the 2007 conference invited registrants to serve as facilitators for twelve networking sessions. This work aims to summarize the conversations that took place during those sessions, based upon notes and artifacts provided to the author by the session facilitators.

  15. CONFERENCES AND SYMPOSIA: Commemoration of the centenary of the birth of Academician L A Artsimovich(Scientific session of the Physical Sciences Division of the Russian Academy of Sciences, 18 February 2009; Joint session of the Research Council of the Russian Research Centre 'Kurchatov Institute', the Presidium of the Russian Academy of Sciences, and the Rosatom State Corporation, 18 March 2009)

    NASA Astrophysics Data System (ADS)

    Khalatnikov, Isaak M.; Fortov, Vladimir E.; Makarov, Aleksandr A.; Fridman, Aleksei M.; Martynenko, Yurii V.

    2009-12-01

    The scientific session of the Physical Sciences Division of the Russian Academy of Sciences (RAS) devoted to the centenary of the birth of Academician L A Artsimovich was held on 18 February 2009 in the conference hall of the P N Lebedev Physical Institute, RAS. The following reports were presented at the session: (1) Khalatnikov I M (L D Landau Institute of Theoretical Physics, RAS, Chernogolovka, Moscow region) "Nonaccidental coincidences (Lev Andreevich Artsimovich)"; (2) Pashinin P P (A M Prokhorov Institute of General Physics, RAS, Moscow) "L A Artsimovich and inertial thermonuclear fusion"; (3) Fortov V E (Institute of Thermophysics of Extreme States of the Joint Institute for High Temperatures, RAS, Moscow) "High-power shock waves and extreme states of plasma"; (4) Fridman A M (Institute of Astronomy, RAS, Moscow) "Prediction and discovery of ultrastrong hydrodynamic instabilities caused by a velocity jump: theory and experiment"; (5) Smirnov V P (Russian Research Centre 'Kurchatov Institute', Moscow) "Retracing Artsimovich's path to the thermonuclear source of energy". On 18 March 2009, a joint session of the Learned Council of the Russian Research Centre 'Kurchatov Institute' (RNTsKI in Russ. abbr.), the Presidium of the Russian Academy of Sciences, and the Rosatom State Corporation took place at RNTsKI; the session was devoted to the 100th anniversary of the birth of Academician L A Artsimovich. The following talks were presented at the session: (1) Velikhov E P (Russian Research Centre 'Kurchatov Institute', Moscow) "Academician L A Artsimovich—the founder of our field of science and industry"; (2) Smirnov V P (Russian Research Centre 'Kurchatov Institute', Moscow) "Retracing Artsimovich's path to the thermonuclear source of energy"; (3) Boyarchuk A A (Division of General Physics and Astronomy, RAS, Moscow) "L A Artsimovich and astronomy"; (4) Martynenko Yu V (Institute of Nuclear Fusion, Russian Research Centre 'Kurchatov Institute', Moscow) "Electromagnetic isotope separation method and its heritage"; (5) Strelkov V S (Institute of Nuclear Fusion, Russian Research Centre 'Kurchatov Institute', Moscow) "Our teacher: Lev Andreevich Artsimovich"; (6) Mirnov S V (Institute of Nuclear Fusion, Russian Research Centre 'Kurchatov Institute', Moscow) "L A Artsimovich through the eyes of a former postgraduate student". • Nonaccidental coincidences (Lev Andreevich Artsimovich), I M Khalatnikov Physics-Uspekhi, 2009, Volume 52, Number 12, Pages 1248-1249 • Avenues for the innovative development of energetics in the world and in Russia, V E Fortov, A A Makarov Physics-Uspekhi, 2009, Volume 52, Number 12, Pages 1249-1265 • Lev Andreevich Artsimovich and extremely strong hydrodynamic instabilities, A M Fridman Physics-Uspekhi, 2009, Volume 52, Number 12, Pages 1265-1266 • Electromagnetic isotope separation method and its heritage, Yu V Martynenko Physics-Uspekhi, 2009, Volume 52, Number 12, Pages 1266-1272

  16. Training for Triggers: Helping Writing Center Consultants Navigate Emotional Sessions

    ERIC Educational Resources Information Center

    Perry, Alison

    2016-01-01

    Labor performed by writing center consultants in sessions is inherently emotional. While writing center professionals can never alleviate fully the emotional demands placed on consultants during sessions, we can work to educate our staff about empathetic engagement with clients, and we can create structures and practices conducive to a supportive…

  17. Cost and logistics for implementing the American College of Surgeons objective structured clinical examination.

    PubMed

    Sudan, Ranjan; Clark, Philip; Henry, Brandon

    2015-01-01

    The American College of Surgeons has developed a reliable and valid OSCE (objective structured clinical examination) to assess the clinical skills of incoming postgraduate year 1 surgery residents, but the cost and logistics of implementation have not been described. Fixed costs included staff time, medical supplies, facility fee, standardized patient (SP) training time, and one OSCE session. Variable costs were incurred for additional OSCE sessions. Costs per resident were calculated and modeled for increasing the number of test takers. American College of Surgeons OSCE materials and examination facilities were free. Fixed costs included training 11 SPs for 4 hours ($1,540), moulage and simulation material ($469), and administrative effort for 44 hours ($2,200). Variable cost for each session was $1,540 (SP time). Total cost for the first session was $6,649 ($664/resident), decreased to $324/resident for 3 sessions, and projected to further decline to $239/resident for 6 sessions. The cost decreased as the number of residents tested increased. To manage costs, testing more trainees by regional collaboration is recommended. Copyright © 2015 Elsevier Inc. All rights reserved.

  18. Quantification of the Spatial Organization of the Nuclear Lamina as a Tool for Cell Classification

    PubMed Central

    Righolt, Christiaan H.; Zatreanu, Diana A.; Raz, Vered

    2013-01-01

    The nuclear lamina is the structural scaffold of the nuclear envelope that plays multiple regulatory roles in chromatin organization and gene expression as well as a structural role in nuclear stability. The lamina proteins, also referred to as lamins, determine nuclear lamina organization and define the nuclear shape and the structural integrity of the cell nucleus. In addition, lamins are connected with both nuclear and cytoplasmic structures forming a dynamic cellular structure whose shape changes upon external and internal signals. When bound to the nuclear lamina, the lamins are mobile, have an impact on the nuclear envelop structure, and may induce changes in their regulatory functions. Changes in the nuclear lamina shape cause changes in cellular functions. A quantitative description of these structural changes could provide an unbiased description of changes in cellular function. In this review, we describe how changes in the nuclear lamina can be measured from three-dimensional images of lamins at the nuclear envelope, and we discuss how structural changes of the nuclear lamina can be used for cell classification. PMID:27335676

  19. Quantification of the Spatial Organization of the Nuclear Lamina as a Tool for Cell Classification.

    PubMed

    Righolt, Christiaan H; Zatreanu, Diana A; Raz, Vered

    2013-01-01

    The nuclear lamina is the structural scaffold of the nuclear envelope that plays multiple regulatory roles in chromatin organization and gene expression as well as a structural role in nuclear stability. The lamina proteins, also referred to as lamins, determine nuclear lamina organization and define the nuclear shape and the structural integrity of the cell nucleus. In addition, lamins are connected with both nuclear and cytoplasmic structures forming a dynamic cellular structure whose shape changes upon external and internal signals. When bound to the nuclear lamina, the lamins are mobile, have an impact on the nuclear envelop structure, and may induce changes in their regulatory functions. Changes in the nuclear lamina shape cause changes in cellular functions. A quantitative description of these structural changes could provide an unbiased description of changes in cellular function. In this review, we describe how changes in the nuclear lamina can be measured from three-dimensional images of lamins at the nuclear envelope, and we discuss how structural changes of the nuclear lamina can be used for cell classification.

  20. Multi-modality imaging: Bird's eye view from the 2016 American Heart Association Scientific Sessions.

    PubMed

    AlJaroudi, Wael A; Lloyd, Steven G; Chaudhry, Farooq A; Hage, Fadi G

    2017-06-01

    This review summarizes key imaging studies that were presented in the American Heart Association Scientific Sessions 2016 related to the fields of nuclear cardiology, cardiac computed tomography, cardiac magnetic resonance, and echocardiography. This bird's eye view will inform readers about multiple studies from these different modalities. We hope that this general overview will be useful for those that did not attend the conference as well as to those that did since it is often difficult to get exposure to many abstracts at large meetings. The review, therefore, aims to help readers stay updated on the newest imaging studies presented at the meeting.

  1. The Intermediate Neutrino Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Adams, C.; Alonso, J. R.; Ankowski, A. M.

    2017-04-03

    The US neutrino community gathered at the Workshop on the Intermediate Neutrino Program (WINP) at Brookhaven National Laboratory February 4-6, 2015 to explore opportunities in neutrino physics over the next five to ten years. Scientists from particle, astroparticle and nuclear physics participated in the workshop. The workshop examined promising opportunities for neutrino physics in the intermediate term, including possible new small to mid-scale experiments, US contributions to large experiments, upgrades to existing experiments, R&D plans and theory. The workshop was organized into two sets of parallel working group sessions, divided by physics topics and technology. Physics working groups covered topicsmore » on Sterile Neutrinos, Neutrino Mixing, Neutrino Interactions, Neutrino Properties and Astrophysical Neutrinos. Technology sessions were organized into Theory, Short-Baseline Accelerator Neutrinos, Reactor Neutrinos, Detector R&D and Source, Cyclotron and Meson Decay at Rest sessions.This report summarizes discussion and conclusions from the workshop.« less

  2. Objective structured brainstorming questions (OSBQs) in PBL tutorial sessions: Evidence based pilot study

    PubMed Central

    AlHoqail, Ibrahim A.; Badr, Fouad M.

    2010-01-01

    The fact that faculty tutors do have different backgrounds and specialty has been a concern as a factor that contributes to disparity in the delivery of brainstorming session outcomes. This paper aims to introduce a road map in the form of a set of focused objective structured questions (OSBQs) for tutors to follow in brainstorming. Methods Objectively structured questions were generated by the block planning committees. A pilot study was conducted from February 2008 – March 2009 and included groups (44 students) of second and third year undergraduate students of the Faculty of Medicine, King Fahad Medical City. Four indicators were considered to check the validity of the proposed OSBQs; (i) feed back on the perception of medical students experiencing different types of tutorial sessions, (ii) learning objectives achieved under both systems, (iii) student’s performance under the OSBQs and the unguided tutorials and (iv) proper utilization of the time allocated to brainstorming sessions. Results The student’s perception of their satisfaction of implementation of OSBQs was unanimous. Student’s performances were much better in blocks implementing OSBQs. The time allocated for brainstorming sessions was efficiently utilized with the introduction of OSBQs. Conclusion Implementation of OSBQs leads to standardization of tutorial sessions and allows more interaction between students to achieve their learning objectives and score better in their exams. Concern over the role of tutors will diminish. PMID:21475549

  3. Objective structured brainstorming questions (OSBQs) in PBL tutorial sessions: Evidence based pilot study.

    PubMed

    Alhoqail, Ibrahim A; Badr, Fouad M

    2010-11-01

    The fact that faculty tutors do have different backgrounds and specialty has been a concern as a factor that contributes to disparity in the delivery of brainstorming session outcomes. This paper aims to introduce a road map in the form of a set of focused objective structured questions (OSBQs) for tutors to follow in brainstorming. Objectively structured questions were generated by the block planning committees. A pilot study was conducted from February 2008 - March 2009 and included groups (44 students) of second and third year undergraduate students of the Faculty of Medicine, King Fahad Medical City. Four indicators were considered to check the validity of the proposed OSBQs; (i) feed back on the perception of medical students experiencing different types of tutorial sessions, (ii) learning objectives achieved under both systems, (iii) student's performance under the OSBQs and the unguided tutorials and (iv) proper utilization of the time allocated to brainstorming sessions. The student's perception of their satisfaction of implementation of OSBQs was unanimous. Student's performances were much better in blocks implementing OSBQs. The time allocated for brainstorming sessions was efficiently utilized with the introduction of OSBQs. Implementation of OSBQs leads to standardization of tutorial sessions and allows more interaction between students to achieve their learning objectives and score better in their exams. Concern over the role of tutors will diminish.

  4. Effects of structured group psychosocial support sessions on psychosocial wellbeing of children and their caregivers: a descriptive study.

    PubMed

    Humeid, Jasem

    2018-02-21

    Children aged 7-12 years and their caregivers participated in a series of group psychosocial support sessions, using standard manuals specifically developed for facilitating such sessions such as Children Affected by Armed Conflict and Joint Sessions. The sessions used various activities, including drawing, storytelling, folk games, and other activities, to provide participants with opportunities to express their feelings, learn and practice new coping skills, and interact with others. The aim of this study was to measure the effects of structured psychosocial support sessions on the psychosocial wellbeing of children and their caregivers in the Gaza Strip. This descriptive study involved children and female caregivers selected from six locations using a stratified sampling technique. External numerators collected data before and after the group sessions. Two interview questionnaires with questions about psychological and social status were used, one for children and one for caregivers. The caregivers' questionnaire also assessed their psychosocial knowledge. Adult participants and caregivers of participating children provided verbal consent. Data were analysed with SPSS, and a p value less than 0·05 indicated significance. 155 children (77 [50%] boys and 78 [50%] girls) and 155 female caregivers were enrolled from a population of 1720 children (50% boys and 50% girls) and 1720 female caregivers. The sessions improved psychosocial wellbeing in participants, with the average psychosocial wellbeing score increasing from 58% to 87% in children and from 69% to 84% in caregivers. Caregivers' knowledge increased from 70% to 82%. Improvement was found in the various aspects of psychosocial wellbeing. No differences were found with respect to location, sex, and age. Structured group sessions improved psychosocial wellbeing in children and caregivers and improved caregivers' knowledge. Given the design of this study, it is difficult to fully attribute these results to the intervention. None. Copyright © 2018 Elsevier Ltd. All rights reserved.

  5. National Nuclear Data Center

    Science.gov Websites

    reaction data Sigma Retrieval & Plotting Nuclear structure & decay Data Nuclear Science References Experimental Unevaluated Nuclear Data List Evaluated Nuclear Structure Data File NNDC databases Ground and isomeric states properties Nuclear structure & decay data journal Nuclear reaction model code Tools and

  6. Multiple data sets converge on a geologic structural model for Glass Buttes, Oregon geothermal prospect, Patrick Walsh, et al, 2010 American Geophysical Union Poster Session

    DOE Data Explorer

    Ezra Zemach

    2010-01-01

    Multiple data sets converge on a geologic structural model for Glass Buttes, Oregon geothermal prospect, Patrick Walsh, Brigette Martini, Chet Lide, Darrick Boschmann, John DIlles, Andrew Meigs, 2010 Ormat Nevada, Zonge Geophysical, Oregon State University American Geophysical Union, Poster Session

  7. PATRAM '80. Proceedings. Volume 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Huebner, H.W.

    1980-01-01

    Volume 2 contains papers from the following sessions: Safeguards-Related Problems; Neutronics and Criticality; Operations and Systems Experience II; Plutonium Systems; Intermediate Storage in Casks; Operations and Systems Planning; Institutional Issues; Structural and Thermal Evaluation I; Poster Session B; Extended Testing I; Structural and Thermal Evaluation II; Extended Testing II; and Emergency Preparedness and Response. Individual papers were processed. (LM)

  8. Observations of youth football training: How do coaches structure training sessions for player development?

    PubMed

    O'Connor, Donna; Larkin, Paul; Williams, A Mark

    2018-01-01

    We used systematic observation tools to explore the structure (i.e., activity and inactivity) and sequencing (i.e., the types of activities used) of football coaching sessions in Australia following the implementation of a new National Curriculum. Youth soccer coaches (n = 34), coaching within the Skill Acquisition (U11-U13 n = 19) and Game Training (U14-U17 n = 15) phases of the Football Federation Australia National Curriculum participated. Participants were filmed during a regular coaching session, with systematic observation of the session undertaken to provide a detailed analysis of the practice activities and coach behaviours. Findings indicated a session comprised of Playing Form activities (40.9%), Training Form activities (22.3%), inactivity (31%), and transitions between activities (5.8%). Coaches prescribed more Training Form activities (e.g., individual (5.4%) and drills (15.1%)) early in the session and progressed to Playing Form activities (i.e., small-sided games (15.3%) then larger games (24.8%)) later in the session. Most inactivity reflected the players listening to the coach - either in a team huddle (9.9%) or frozen on the spot during an activity (16.5%). In addition, coaches generally spent over 3 min communicating to players prior to explaining and introducing an activity regardless of when in the session the activity was scheduled.

  9. Nineteenth International Cosmic Ray Conference. HE Sessions, Volume 6

    NASA Technical Reports Server (NTRS)

    Jones, F. C. (Compiler)

    1985-01-01

    Papers contributed to the 19th International Cosmic Ray Conference which address high energy interactions and related phenomena are compiled. Particular topic areas include cross sections; particle production; nuclei and nuclear matter; nucleus-nucleus collisions; gamma ray and hadron spectra; C-jets, a-jets, and super families; and emulsion chamber simulations.

  10. 77 FR 40914 - In the Matter of Indiana Michigan Power Company, D. C. Cook Nuclear Power Plant; Confirmatory...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-07-11

    ... Company met in an ADR session mediated by a professional mediator, arranged through Cornell University's... counsel or representative) to digitally sign documents and access the E-Submittal server for any... requirements for accessing the E-Submittal server are detailed in the NRC's ``Guidance for Electronic...

  11. TH-AB-206-01: Advances in Radionuclide Therapy - From Radioiodine to Nanoparticles

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Humm, J.

    In the past few decades, the field of nuclear medicine has made long strides with the continued advancement of related sciences and engineering and the availability of diagnostic and therapeutic radionuclides. Leveraging these advancements while combining the advantages of therapeutic and diagnostic radionuclides into one radiopharmaceutical has also created a new subfield “theranostics” in nuclear medicine that has the potential to further propel the field into the future. This session is composed of two talks; one focused on the physics principles of theranostics from properties of beta and alpha emitting radionuclides to dosimetric models and quantification; while the second describesmore » preclinical and clinical applications of theranostics and discusses the challenges and opportunities of bringing them to the clinic. At the end of the session the listener should be able to identify: The different properties of beta and alpha emitting radionuclides Which radionuclides are selected for which nuclear medicine therapies and why How PET can be used to accurately quantify the uptake of tumor targeting molecules How individualized dosimetry can be performed from the management of thyroid cancer to novel radiolabeled antibody therapies Promising pre-clinical radiopharmaceutical pairs in prostate cancer and melanoma. Promising clinical Theranostics in neuroendocrine cancers. Challenges of bringing Theranostics to the clinic. E. Delpassand, RITA Foundation -Houston; SBIR Grant; CEO and share holder of RadioMedix.« less

  12. PREFACE: International Conference on Computing in High Energy and Nuclear Physics (CHEP'07)

    NASA Astrophysics Data System (ADS)

    Sobie, Randall; Tafirout, Reda; Thomson, Jana

    2007-07-01

    The 2007 International Conference on Computing in High Energy and Nuclear Physics (CHEP) was held on 2-7 September 2007 in Victoria, British Columbia, Canada. CHEP is a major series of international conferences for physicists and computing professionals from the High Energy and Nuclear Physics community, Computer Science and Information Technology. The CHEP conference provides an international forum to exchange information on computing experience and needs for the community, and to review recent, ongoing, and future activities. The CHEP'07 conference had close to 500 attendees with a program that included plenary sessions of invited oral presentations, a number of parallel sessions comprising oral and poster presentations, and an industrial exhibition. Conference tracks covered topics in Online Computing, Event Processing, Software Components, Tools and Databases, Software Tools and Information Systems, Computing Facilities, Production Grids and Networking, Grid Middleware and Tools, Distributed Data Analysis and Information Management and Collaborative Tools. The conference included a successful whale-watching excursion involving over 200 participants and a banquet at the Royal British Columbia Museum. The next CHEP conference will be held in Prague in March 2009. We would like thank the sponsors of the conference and the staff at the TRIUMF Laboratory and the University of Victoria who made the CHEP'07 a success. Randall Sobie and Reda Tafirout CHEP'07 Conference Chairs

  13. Advanced Insider Threat Mitigation Workshop Instructional Materials

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gibbs, Philip; Larsen, Robert; O'Brien, Mike

    Insiders represent a formidable threat to nuclear facilities. This set of workshop materials covers methodologies to analyze and approaches to mitigate the threat of an insider attempting abrupt and protracted theft of nuclear materials. This particular set of materials is an update of a January 2008 version to add increased emphasis on Material Control and Accounting and its role with respect to protracted insider nuclear material theft scenarios. This report is a compilation of workshop materials consisting of lectures on technical and administrative measures used in Physical Protection (PP) and Material Control and Accounting (MC&A) and methods for analyzing theirmore » effectiveness against a postulated insider threat. The postulated threat includes both abrupt and protracted theft scenarios. Presentation is envisioned to be through classroom instruction and discussion. Several practical and group exercises are included for demonstration and application of the analysis approach contained in the lecture/discussion sessions as applied to a hypothetical nuclear facility.« less

  14. International nuclear safety concerns. Hearing before the Subcommittee on Energy, Nuclear Proliferation, and Government Processes of the Committee on Governmental Affairs, United States Senate, Ninety-Ninth Congress, Second Session, May 8, 1986

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1986-01-01

    Allan I. Mendelowitz of the General Accounting Office (GAO) and James R. Shea of the Nuclear Regulatory Commission were the principal witnesses at a hearing on international concerns about reactor safety. The hearing focused on the Soviet accident at Chernobyl as a demonstration that safety matters are a legitimate area of international concern. Among the issues under discussion were safety standards and inspection procedures of the International Atomic Energy Agency (IAEA). Estimates developed by the GAO show that developing countries, which lack a strong technical base or nuclear background to handle emergencies, will have half the reactors in the worldmore » by the year 2000. Mendelowitz and Shea, together with supporting testimony from others in their agencies described international efforts to improve safeguards.« less

  15. Proceedings of the Joint IAEA/CSNI Specialists` Meeting on Fracture Mechanics Verification by Large-Scale Testing held at Pollard Auditorium, Oak Ridge, Tennessee

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pugh, C.E.; Bass, B.R.; Keeney, J.A.

    This report contains 40 papers that were presented at the Joint IAEA/CSNI Specialists` Meeting Fracture Mechanics Verification by Large-Scale Testing held at the Pollard Auditorium, Oak Ridge, Tennessee, during the week of October 26--29, 1992. The papers are printed in the order of their presentation in each session and describe recent large-scale fracture (brittle and/or ductile) experiments, analyses of these experiments, and comparisons between predictions and experimental results. The goal of the meeting was to allow international experts to examine the fracture behavior of various materials and structures under conditions relevant to nuclear reactor components and operating environments. The emphasismore » was on the ability of various fracture models and analysis methods to predict the wide range of experimental data now available. The individual papers have been cataloged separately.« less

  16. Distributed Training Enhances Implicit Sequence Acquisition in Children with Specific Language Impairment

    ERIC Educational Resources Information Center

    Desmottes, Lise; Meulemans, Thierry; Patinec, Marie-Aude; Maillart, Christelle

    2017-01-01

    Purpose: This study explored the effects of 2 different training structures on the implicit acquisition of a sequence in a serial reaction time (SRT) task in children with and without specific language impairment (SLI). Method: All of the children underwent 3 training sessions, followed by a retention session 2 weeks after the last session. In the…

  17. PREFACE: NUBA Conference Series 1: Nuclear Physics and Astrophysics

    NASA Astrophysics Data System (ADS)

    Boztosun, I.; Balantekin, A. B.; Kucuk, Y.

    2015-04-01

    The international conference series ''NUBA Conference Series 1: Nuclear Physics and Astrophysics'' was held on September 14-21 2014 in Antalya-Turkey. Akdeniz University hosted the conference and the Adrasan Training and Application Centre was chosen as a suitable venue to bring together scientists from all over the world as well as from different parts of Turkey. The conference was supported by the Scientific and Technological Research Council of Turkey (TÜBìTAK) and Akdeniz University Nuclear Sciences Application and Research Center (NUBA). Based on the highly positive remarks received from the participants both during and after the conference, we believe that the event has proven to be a fulfilling experience for all those who took part. The conference provided an opportunity for the participants to share their ideas and experiences in addition to exploring possibilities for future collaborations. Participants of the conference focused on: • Nuclear Structure and Interactions • Nuclear Reactions, • Photonuclear Reactions and Spectroscopy • Nuclear and Particle Astrophysics • Nuclear Processes in Early Universe • Nuclear Applications • New Facilities and Instrumentation Participants included a number of distinguished invited speakers. There was significant interest from the international nuclear physics community and numerous abstracts and papers were submitted. The scientific committee conducted a careful and rigorous selection process, as a result of which 75 contributions were accepted. Of those, 65 of them were given as oral and 10 as poster presentations. The superb quality of the papers ensured fruitful discussion sessions. We thank all the participants for their efforts and also for promptly sending in their papers for publication. This issue of the Journal of Physics: Conference Series was peer-reviewed by expert referees and we also thank them for peer-reviewing the papers. The national and international advisory committee also deserve appreciation for their involvement in the shaping of the conference programme. The local organizing committee, Mesut Karakoç, Haris Djapo, Fatih Ozmen and Deniz Kaya worked diligently and ensured that the programme ran smoothly. We sincerely thank them all. Our final thanks go to IOP for publishing the proceedings in a most timely and meticulous manner. We hope to see the participants again in Turkey, in the second conference of this series.

  18. The effects of kinetic structure and micrograph content on achievement in reading micrographs by college biology students

    NASA Astrophysics Data System (ADS)

    Johnson, Virginia Abbott; Lockard, J. David

    The effects of kinetic structure and micrograph content on student achievement of reading micrograph skills were examined. The purpose of the study was to determine which form of kinetic structure, high or low, and/or micrograph content, unified or varied, was most effective and if there were any interactive effects. Randomly assigned to four treatment groups, 100 introductory college biology students attended three audiovisual presentations and practice sessions on reading light, transmission electron, and scanning electron micrographs. The micrograph skills test, administered at two points in time, assessed knowledge acquisition and retention. The test measured general concept skills and actual reading micrograph skills separately. All significant tests were considered with an = 0.05. High kinetic structure was found to be more effective than low kinetic structure in developing general concepts about micrographs. This finding supports Anderson's kinetic theory research. High kinetic structure instruction does not affect actual reading micrograph skills, but micrograph content does. Unified micrograph content practice sessions were more effective than varied micrograph content practice sessions. More attention should be given to the visual components of perceptual learning tasks.

  19. 100th anniversary of the birth of B M Pontecorvo (Scientific session of the Physical Sciences Division of the Russian Academy of Sciences, 2 September 2013)

    NASA Astrophysics Data System (ADS)

    2014-05-01

    A scientific session "Prospects of Studies in Neutrino Particle Physics and Astrophysics," of the Physical Sciences Division of the Russian Academy of Sciences (DPS RAS), devoted to the centenary of B M Pontecorvo, was held on 2-3 September 2014 at the JINR international conference hall (Dubna, Moscow region).The following reports were put on the session agenda as posted on the website http://www.gpad.ac.ru of the RAS Physical Sciences Division: (1) Kudenko Yu G (Institute for Nuclear Research, RAS, Moscow; Moscow Institute of Physics and Technology, Dolgoprudnyi, Moscow region; National Research Nuclear University MEPhI, Moscow) "Long-baseline neutrino accelerator experiments: results and prospects";(2) Spiering Ch (Deutsches Elektronen-Synchrotron (DESY), Germany) "Results obtained by ICECUBE and prospects of neutrino astronomy";(3) Barabash A S (Alikhanov Institute for Theoretical and Experimental Physics, Moscow) "Double beta decay experiments: current status and prospects";(4) Bilenky S M (Joint Institute for Nuclear Research, Dubna, Moscow region; Technische Universitat M'unchen, Garching, Germany) "Bruno Pontecorvo and the neutrino";(5) Olshevskiy A G (Joint Institute for Nuclear Research, Dubna, Moscow region) "Reactor neutrino experiments: results and prospects";(6) Gavrin V N (Institute for Nuclear Research, RAS, Moscow) "Low-energy neutrino research at the Baksan Neutrino Laboratory";(7) Gorbunov D S (Institute for Nuclear Research, RAS, Moscow): "Sterile neutrinos and their role in particle physics and cosmology";(8) Derbin A V (Konstantinov Petersburg Nuclear Physics Institute, Gatchina, Leningrad region) "Solar neutrino experiments";(9) Rubakov V A (Institute for Nuclear Research, RAS, Moscow) "Prospects of studies in the field of neutrino particle physics and astrophysics." An article by V N Gavrin, close in essence to talk 6, was published in Usp. Fiz. Nauk 181 (9), 975 (2011) [Phys. Usp. 54 (9) 941 (2011)]. Articles by V A Rubakov, close in essence to talk 9, were published in Usp. Fiz. Nauk 182 (10) 1017 (2012); 181 (6) 655 (2011) [Phys. Usp. 55 (10) 949 (2012); 54 (6) 633 (2011)]. Articles based on talks 1-5, 7, and 8 are published below. • Long-baseline neutrino accelerator experiments: results and prospects, Yu G Kudenko Physics-Uspekhi, 2014, Volume 57, Number 5, Pages 462-469 • High-energy neutrino astronomy: a glimpse of the promised land, Ch Spiering Physics-Uspekhi, 2014, Volume 57, Number 5, Pages 470-481 • Double beta decay experiments: current status and prospects, A S Barabash Physics-Uspekhi, 2014, Volume 57, Number 5, Pages 482-488 • Bruno Pontecorvo and the neutrino, S M Bilenky Physics-Uspekhi, 2014, Volume 57, Number 5, Pages 489-496 • Reactor neutrino experiments: results and prospects, A G Olshevskiy Physics-Uspekhi, 2014, Volume 57, Number 5, Pages 497-502 • Sterile neutrinos and their role in particle physics and cosmology, D S Gorbunov Physics-Uspekhi, 2014, Volume 57, Number 5, Pages 503-511 • Solar neutrino experiments, A V Derbin Physics-Uspekhi, 2014, Volume 57, Number 5, Pages 512-524

  20. Preface

    NASA Astrophysics Data System (ADS)

    L'Hostis, Valérie; Foct, François; Féron, Damien

    2006-11-01

    The reinforced concrete is widely used in the construction of nuclear power plants, of nuclear facilities and structures for long-term storage and the disposal of radioactive waste. Indeed this kind of material is used for many purposes, including support, containment, and environmental protection for different types of facilities: e.g. surface structures, shallow subsurface vaults and deep underground repositories. These structures are required to besafe and reliable in challenging and varying environments for periods of time that can potentially range up to several hundred years. During their operational life, these structures will in all likelihood be subjected to a number of environmental stresses or ageing factors that may adversely affect their performance and result in shortened service lives. The detection and assessment of the magnitude as well as the rate of occurrence of any environmental factor-related degradation are key factors in maintaining the capability of these structures to meet their operational requirements. As the knowledge base for modern concretes, such as would be used in fuel cycle-related facilities, is relatively new (i.e. about, 100 years versus the required 200 to 500 or more years), additional inputs are required in several areas to ensure that these structures will continue to meet their design requirements throughout their operational life. Within this context, the international Workshop entitled "NUCPERF 2006, Corrosion and Long Term Performance of Concrete in NPP and Waste Facilities" (EFC Event 284) was held at Cadarache (France), on 27-30 March 2006. Its purpose was to bring together scientists and engineers from various countries that are developing nuclear power generation and/or waste disposal programmes. A special focus has been made on the discussion on R& D progress with regard to concrete degradation and corrosion of steel reinforcements in order to reach a consensus on R& D needs to further develop cooperative programmes. The sessions of the workshop covered the following areas, from fundamental aspects to technically relevant industrial applications: - Present and Future Expectations on regulations, design codes and R& D programmes; - Experimental Studies mainly focused on corrosion of embedded steels and its mechanical consequences, reactive agents transport and chemical degradation of concrete; - Phenomenological Modelling of the different mechanisms involved in reinforced concrete degradation (corrosion, transport, mechanics, etc.); - Service Life Models focused on the assessment of reinforced concrete structures and life cycle analysis; - Feedback Experience use of field experiences and archaeological artefacts for the phenomenological understanding and modelling; - Monitoring and Repair on-site corrosion evaluation, repairing techniques performance... The organisation and the success of this Workshop have been made possible thanks to CEA (Commissariat à l'Énergie Atomique) and EDF (Électricité de France) which co-organised this event. It was co-sponsored by EFC/WP4 (European Federation of Corrosion, Nuclear corrosion working party) and OECD/NEA (Nuclear Energy Agency) which the editors want to warmly thank for their active scientific and practical contributions. The editors would also like to thank the authors who presented papers of outstanding scientific content and who responded enthusiastically to the discussions and questions raised during the Workshop, the programme committee, who had to make the tricky selection of the presented papers, and finally the reviewers of the papers presented in this special issue. This Workshop was a forum to exchange state-of-the-art knowledge on corrosion and long-term performance of concrete in nuclear power plants and waste facilities. The editors hope that the scientific results gathered in these proceedings will be useful to scientists and engineers in the field of reinforced concrete materials for nuclear applications. Valérie L'Hostis, François Foct and Damien Féron Editors of this Special Issue

  1. Nuclear Data Networks

    Science.gov Websites

    calibrations. NSDD The international network of Nuclear Structure and Decay Data evaluators Group of and updating of nuclear structure data contained in Evaluated Nuclear Structure Data File (ENSDF

  2. PREFACE: EPS Euroconference XIX Nuclear Physics Divisional Conference: New Trends in Nuclear Physics Applications and Technology

    NASA Astrophysics Data System (ADS)

    2006-06-01

    It was with great pleasure that the Department of Nuclear and Theoretical Physics of the University of Pavia and the INFN (Istituto Nazionale di Fisica Nucleare) Structure of Pavia organised the XIX Nuclear Physics Divisional Conference of the European Physical Society, which was held in the historical buildings of the University of Pavia from 5-9 September 2005. The Conference was devoted to the discussion of the most recent experimental and theoretical achievements in the field of Nuclear Physics applications, as well as of the latest developments in technological tools related to Nuclear Physics research. The University of Pavia has a long tradition in Physics and in Applied Physics, being the site where Alessandro Volta developed his "pila", the precursor of the modern battery. This is the place where the first experiments with electricity were conducted and where the term "capacitance" used for capacitors was invented. Today the University hosts a Triga Mark II nuclear reactor, which is used by the Departments of the University of Pavia and by other Universities and private companies as well. Moreover, Pavia is the site selected for the construction of the CNAO complex "Centro Nazionale di Adroterapia Oncologica" (National Centre for Oncological Hadrontherapy), planned for 2005-2008 which represents a unique facility in Italy and will be among the first complexes of this type in Europe. The Conference has gathered together experts in various fields from different countries and has been the occasion to review the present status and to discuss the new emerging trends in Nuclear Physics and its applications to multidisciplinary researches and the development of new technologies. The following topics were treated: Nuclear Techniques in Medicine and Life Sciences (Cancer Therapy, new Imaging and Diagnostics Tools, Radioisotope production, Radiation Protection and Dosimetry). Applications of Nuclear Techniques in Art, Archaeometry and other Interdisciplinary fields. Role of Nuclear Techniques in Environment Problems. Applications of Nuclear Techniques relevant for Civil Security (contraband and explosive detection, search for Weapons of Mass Destruction, Nuclear Safeguards). Nuclear Applications in Space Research. Material and Structure Testing in Research and Industry. New contributions of Nuclear Techniques to the solution of the Energy Production problems and Nuclear Waste Transmutation. Emerging experimental techniques, new detectors and new modeling tools. During the Monday morning Session of the Conference, the 2005 IBA-EUROPHYSICS PRIZE for Applied Nuclear Science and Nuclear Methods in Medicine, sponsored by the Belgian company IBA, was awarded to the two laureates Werner Heil (Mainz) and Pierre Jean Nacher (Paris) for the development of spin polarized 3He targets by optical pumping and their applications in nuclear science and medicine. The meeting was a real success, with 18 invited talks, 66 contributed talks and 31 posters and an overall participation, during five full days, of around 150 scientists from different European and non-European countries. It also hosted a three day industrial exhibition of a selection of Companies that sponsored the event. The Organisers take thos opportunity to thank the University of Pavia, the Amministrazione Comunale di Pavia and the Provincia di Pavia, as well as all exhibitors (Ametek, Ansaldo Superconduttori, Caen, Else, Hamamatsu, IBA, Micos, Micron Semiconductor), for their support of the Conference. The Organisers finally wish to thank the Scientific Secretary of the Conference, Dr Andrea Fontana of INFN Pavia, for the huge amount of work done in preparing the Conference, Mr Claudio Casella of the Department of Nuclear and Theoretical Physics of the University of Pavia for technical support and the Conference staff, Dr Gaia Boghen and the graduate students Federica Devecchi and Silvia Franchino, for their invaluable help. The very effective and professional work of the staff of PRAGMA Congressi, who took charge of all the administrative and accommodation procedures, is also acknowledged. The Local Organizing Committee (Pavia, January 2006)

  3. Different acute cardiovascular stress in response to resistance exercise leading to failure versus not to failure in elderly women with and without hypertension--a pilot study.

    PubMed

    Tajra, Vitor; Vieira, Denis C L; Tibana, Ramires A; Teixeira, Tatiane G; Silva, Alessandro O; Farias, Darlan L; Nascimento, Dahan da C; de Sousa, Nuno M F; Willardson, Jeffrey; Prestes, Jonato

    2015-03-01

    The purpose of the present study was to compare the effects of resistance exercise (RE) leading to failure versus not to failure on 24-h blood pressure (BP) and rate-pressure product (RPP) responses in normotensive and hypertensive trained elderly women. Seven normotensive women and seven women with medically documented hypertension randomly performed three experimental sessions: (i) a non-exercise control session that involved 30 min of seated rest, (ii) whole body RE leading to failure that involved three sets with an eight repetitions maximum (8RM) load and (iii) whole body RE not to failure that involved three sets with 70% of an 8RM load. Systolic BP (SBP), diastolic BP (DBP) and mean BP (MBP) responses during each hour of sleep and awake states were measured. Results of all subjects revealed that the RPP was higher (P ≤ 0.05) during afternoon and night hours after the RE session leading to failure versus not to failure and the non-exercise control session. For the hypertensive group during the night hours, SBP remained higher after the RE session not to failure (P = 0.047) versus non-exercise control session. For the normotensive group, DBP remained higher after the RE session leading to failure over the 24-h period (approximately 8 mmHg h(-1), P = 0.044) and the period upon awaking (approximately 5 mmHg h(-1), P = 0.044) versus the hypertensive group. The normotensive elderly women of this pilot study presented a greater cardiovascular response to RE leading to failure, as a consequence of the higher training intensity. © 2014 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  4. Reactor Dosimetry State of the Art 2008

    NASA Astrophysics Data System (ADS)

    Voorbraak, Wim; Debarberis, Luigi; D'Hondt, Pierre; Wagemans, Jan

    2009-08-01

    Oral session 1: Retrospective dosimetry. Retrospective dosimetry of VVER 440 reactor pressure vessel at the 3rd unit of Dukovany NPP / M. Marek ... [et al.]. Retrospective dosimetry study at the RPV of NPP Greifswald unit 1 / J. Konheiser ... [et al.]. Test of prototype detector for retrospective neutron dosimetry of reactor internals and vessel / K. Hayashi ... [et al.]. Neutron doses to the concrete vessel and tendons of a magnox reactor using retrospective dosimetry / D. A. Allen ... [et al.]. A retrospective dosimetry feasibility study for Atucha I / J. Wagemans ... [et al.]. Retrospective reactor dosimetry with zirconium alloy samples in a PWR / L. R. Greenwood and J. P. Foster -- Oral session 2: Experimental techniques. Characterizing the Time-dependent components of reactor n/y environments / P. J. Griffin, S. M. Luker and A. J. Suo-Anttila. Measurements of the recoil-ion response of silicon carbide detectors to fast neutrons / F. H. Ruddy, J. G. Seidel and F. Franceschini. Measurement of the neutron spectrum of the HB-4 cold source at the high flux isotope reactor at Oak Ridge National Laboratory / J. L. Robertson and E. B. Iverson. Feasibility of cavity ring-down laser spectroscopy for dose rate monitoring on nuclear reactor / H. Tomita ... [et al.]. Measuring transistor damage factors in a non-stable defect environment / D. B. King ... [et al.]. Neutron-detection based monitoring of void effects in boiling water reactors / J. Loberg ... [et al.] -- Poster session 1: Power reactor surveillance, retrospective dosimetry, benchmarks and inter-comparisons, adjustment methods, experimental techniques, transport calculations. Improved diagnostics for analysis of a reactor pulse radiation environment / S. M. Luker ... [et al.]. Simulation of the response of silicon carbide fast neutron detectors / F. Franceschini, F. H. Ruddy and B. Petrović. NSV A-3: a computer code for least-squares adjustment of neutron spectra and measured dosimeter responses / J. G. Williams, A. P. Ribaric and T. Schnauber. Agile high-fidelity MCNP model development techniques for rapid mechanical design iteration / J. A. Kulesza.Extension of Raptor-M3G to r-8-z geometry for use in reactor dosimetry applications / M. A. Hunter, G. Longoni and S. L. Anderson. In vessel exposure distributions evaluated with MCNP5 for Atucha II / J. M. Longhino, H. Blaumann and G. Zamonsky. Atucha I nuclear power plant azimutal ex-vessel flux profile evaluation / J. M. Longhino ... [et al.]. UFTR thermal column characterization and redesign for maximized thermal flux / C. Polit and A. Haghighat. Activation counter using liquid light-guide for dosimetry of neutron burst / M. Hayashi ... [et al.]. Control rod reactivity curves for the annular core research reactor / K. R. DePriest ... [et al.]. Specification of irradiation conditions in VVER-440 surveillance positions / V. Kochkin ... [et al.]. Simulations of Mg-Ar ionisation and TE-TE ionisation chambers with MCNPX in a straightforward gamma and beta irradiation field / S. Nievaart ... [et al.]. The change of austenitic stainless steel elements content in the inner parts of VVER-440 reactor during operation / V. Smutný, J. Hep and P. Novosad. Fast neutron environmental spectrometry using disk activation / G. Lövestam ... [et al.]. Optimization of the neutron activation detector location scheme for VVER-lOOO ex-vessel dosimetry / V. N. Bukanov ... [et al.]. Irradiation conditions for surveillance specimens located into plane containers installed in the WWER-lOOO reactor of unit 2 of the South-Ukrainian NPP / O. V. Grytsenko. V. N. Bukanov and S. M. Pugach. Conformity between LRO mock-ups and VVERS NPP RPV neutron flux attenuation / S. Belousov. Kr. Ilieva and D. Kirilova. FLUOLE: a new relevant experiment for PWR pressure vessel surveillance / D. Beretz ... [et al.]. Transport of neutrons and photons through the iron and water layers / M. J. Kost'ál ... [et al.]. Condition evaluation of spent nuclear fuel assemblies from the first-generation nuclear-powered submarines by gamma scanning / A. F. Usatyi. L. A. Serdyukova and B. S. Stepennov -- Oral session 3: Power plant surveillance. Upgraded neutron dosimetry procedure for VVER-440 surveillance specimens / V. Kochkin ... [et al.]. Neutron dosimetry on the full-core first generation VVER-440 aimed to reactor support structure load evaluation / P. Borodkin ... [et al.]. Ex-vessel neutron dosimetry programs for PWRs in Korea / C. S. Yoo. B. C. Kim and C. C. Kim. Comparison of irradiation conditions of VVER-1000 reactor pressure vessel and surveillance specimens for various core loadings / V. N. Bukanov ... [et al.]. Re-evaluation of dosimetry in the new surveillance program for the Loviisa 1 VVER-440 reactor / T. Serén -- Oral session 4: Benchmarks, intercomparisons and adjustment methods. Determination of the neutron parameter's uncertainties using the stochastic methods of uncertainty propagation and analysis / G. Grégoire ... [et al.].Covariance matrices for calculated neutron spectra and measured dosimeter responses / J. G. Williams ... [et al.]. The role of dosimetry at the high flux reactor / S. C. van der Marek ... [et al.]. Calibration of a manganese bath relative to Cf-252 nu-bar / D. M. Gilliam, A. T. Yue and M. Scott Dewey. Major upgrade of the reactor dosimetry interpretation methodology used at the CEA: general principle / C. Destouches ... [et al.] -- Oral session 5: power plant surveillance. The role of ex-vessel neutron dosimetry in reactor vessel surveillance in South Korea / B.-C. Kim ... [et al.]. Spanish RPV surveillance programmes: lessons learned and current activities / A. Ballesteros and X. Jardí. Atucha I nuclear power plant extended dosimetry and assessment / H. Blaumann ... [et al.]. Monitoring of radiation load of pressure vessels of Russian VVER in compliance with license amendments / G. Borodkin ... [et al.] -- Poster session 2: Test reactors, accelerators and advanced systems; cross sections, nuclear data, damage correlations. Two-dimensional mapping of the calculated fission power for the full-size fuel plate experiment irradiated in the advanced test reactor / G. S. Chang and M. A. Lillo. The radiation safety information computational center: a resource for reactor dosimetry software and nuclear data / B. L. Kirk. Irradiated xenon isotopic ratio measurement for failed fuel detection and location in fast reactor / C. Ito, T. Iguchi and H. Harano. Characterization of dosimetry of the BMRR horizontal thimble tubes and broad beam facility / J.-P. Hu, R. N. Reciniello and N. E. Holden. 2007 nuclear data review / N. E. Holden. Further dosimetry studies at the Rhode Island nuclear science / R. N. Reciniello ... [et al.]. Characterization of neutron fields in the experimental fast reactor Joyo MK-III core / S. Maeda ... [et al.]. Measuring [symbol]Li(n, t) and [symbol]B(n, [symbol]) cross sections using the NIST alpha-gamma apparatus / M. S. Dewey ... [et al.]. Improvement of neutron/gamma field evaluation for restart of JMTR / Y. Nagao ... [et al.]. Monitoring of the irradiated neutron fluence in the neutron transmutation doping process of HANARO / M.-S. Kim and S.-J. Park.Training reactor VR-l neutron spectrum determination / M. Vins, A. Kolros and K. Katovsky. Differential cross sections for gamma-ray production by 14 MeV neutrons on iron and bismuth / V. M. Bondar ... [et al.]. The measurements of the differential elastic neutron cross-sections of carbon for energies from 2 to 133 ke V / O. Gritzay ... [et al.]. Determination of neutron spectrum by the dosimetry foil method up to 35 Me V / S. P. Simakov ... [et al.]. Extension of the BGL broad group cross section library / D. Kirilova, S. Belousov and Kr. Ilieva. Measurements of neutron capture cross-section for tantalum at the neutron filtered beams / O. Gritzayand V. Libman. Measurements of microscopic data at GELINA in support of dosimetry / S. Kopecky ... [et al.]. Nuclide guide and international chart of nuclides - 2008 / T. Golashvili -- Oral session 6: Test reactors, accelerators and advanced systems. Neutronic analyses in support of the HFIR beamline modifications and lifetime extension / I. Remec and E. D. Blakeman. Characterization of neutron test facilities at Sandia National Laboratories / D. W. Vehar ... [et al.]. LYRA irradiation experiments: neutron metrology and dosimetry / B. Acosta and L. Debarberis. Calculated neutron and gamma-ray spectra across the prismatic very high temperature reactor core / J. W. Sterbentz. Enhancement of irradiation capability of the experimental fast reactor joyo / S. Maeda ... [et al.]. Neutron spectrum analyses by foil activation method for high-energy proton beams / C. H. Pyeon ... [et al.] -- Oral session 7: Cross sections, nuclear data, damage correlations. Investigation of new reaction cross-section evaluations in order to update and extend the IRDF-2002 reactor dosimetry library / É. M. Zsolnay, H. J. Nolthenius and A. L. Nichols. A novel approach towards DPA calculations / A. Hogenbirk and D. F. Da Cruz. A new ENDFIB-VII.O based multigroup cross-section library for reactor dosimetry / F. A. Alpan and S. L. Anderson. Activities at the NEA for dosimetry applications / H. Henriksson and I. Kodeli. Validation and verification of covariance data from dosimetry reaction cross-section evaluations / S. Badikov. Status of the neutron cross section standards / A. D. Carlson -- Oral session 8: transport calculations. A dosimetry assessment for the core restraint of an advanced gas cooled reactor / D. A. Thornton ... [et al.]. Neutron dosimetry study in the region of the support structure of a VVER-1000 type reactor / G. Borodkin ... [et al.]. SNS moderator poison design and experiment validation of the moderator performance / W. Lu ... [et al.]. Analysis of OSIRIS in-core surveillance dosimetry for GONDOLE steel irradiation program by using TRIPOLI-4 Monte Carlo code / Y. K. Lee and F. Malouch.Reactor dosimetry applications using RAPTOR-M3G: a new parallel 3-D radiation transport code / G. Longoni and S. L. Anderson.

  5. The Shock and Vibration Bulletin. Part 2. Opening Session, Panel Session, Shock Testing and Analysis, Fluid-structure Topics

    DTIC Science & Technology

    1976-08-01

    would like to 20 g’s rms and this would be instead of the to mention is that the IES under the leadership present single frequency non resonant 2.2 g am...Vol. 11, 1970. 19. Thomson, W. T., Vibration Theory 7. Cremer , L. and Heckl, M. and and Applications, Prentice-Hall, Ungar, E. E., Structure-Borne

  6. FOREWORD: Nuclear Physics in Astrophysics V

    NASA Astrophysics Data System (ADS)

    Auerbach, Naftali; Hass, Michael; Paul, Michael

    2012-02-01

    The fifth edition of the bi-annual 'Nuclear Physics in Astrophysics (NPA)' conference series was held in Eilat, Israel on April 3-8, 2011. This Conference is also designated as the 24th Nuclear Physics Divisional Conference of the EPS. The main purpose of this conference, as that of the four previous ones in this series, is to deal with those aspects of nuclear physics that are directly related to astrophysics. The concept of such a meeting was conceived by the Nuclear Physics Board of the European Physical Society in 1998. At that time, the idea of such a conference was quite new and it was decided that this meeting would be sponsored by the EPS. The first meeting, in January 2001, was planned and organized in Eilat, Israel. Due to international circumstances the conference was moved to Debrecen, Hungary. Subsequent conferences were held in Debrecen again, in Dresden, Germany, and in Frascati, Italy (moved from Gran Sasso due to the tragic earthquake that hit the L'Aquila region). After 10 years the conference finally returned to Eilat, the originally envisioned site. Eilat is a resort town located on the shore of the Gulf of Eilat, which connects Israel to the Red Sea and further south to the Indian Ocean. It commands spectacular views of the desert and mountains, offering unique touristic attractions. The local scientific backdrop of the conference is the fact that the Israeli scientific scene exhibits a wide variety of research activities in many areas of nuclear physics and astrophysics. A new accelerator, SARAF at Soreq Nuclear Research Center is presently undergoing final acceptance tests. SARAF will serve as a platform for production of radioactive ion beams and nuclear-astrophysics research in Israel. The meeting in Eilat was organized by four Israeli scientific institutions, Hebrew University, Soreq Nuclear Research Center, Tel Aviv University and the Weizmann Institute of Science. The welcome reception and lectures were held at the King Solomon hotel and the conference dinner banquet at the Dan hotel. An excursion to the 'Red Canyon' in the Eilat Mountains on Wednesday afternoon was one of the social highlights of the conference. A total number of 140 scientists attended NPA5 and about 30 accompanying persons; about 25% of these were young participants (less than 36 years old). 23 participants were from Israel, and 27 were from outside of Europe (including two from Africa). The subjects covered at the conference in Eilat concentrated mainly on the spirit of the original idea - to probe experimental and theoretical activity in nuclear structure and reactions that is directly related to the physics of the Universe. There were also sessions of general interest in astrophysics, as well as a poster session on Tuesday evening featuring 40 posters. The topics included: Nuclear Structure - Theory and Experiment Big-Bang Nucleosynthesis and Formation of First Stars Stellar Reactions and Solar Neutrinos Explosive Nucleosynthesis, Radioactive Beams and Exotic Nuclei-New Facilities and Future Possibilities for Astrophysics Neutrino Physics - the Low and High-Energy Frontiers Rare events, Dark Matter, Double beta-decay, Symmetries The conference started with an excellent exposé of the progress made in the discovery of super-heavy elements and the study of their properties. The progress in this field is enormous, and this subject should be communicated to more general audiences. The role of the nuclear equation of state and of the precise determination of nuclear masses in nucleosynthesis was emphasized in several talks. The role of neutrinos in astrophysics was discussed extensively in several sessions. One of the highlights of this was the presentation about the IceCube and DeepCore detectors operating deep in the Antarctic ice. These facilities are able to detect cosmogenic neutrinos in a wide energy range, from 10 GeV to 1010 GeV. The subject of solar neutrinos was discussed in a number of talks. Topics related to properties of neutrinos, such as double-beta decay and neutrino mixing were well represented at the conference. One of the central problems in modern cosmology and astrophysics is the search for dark matter. Several talks dealt with this subject and with methods to detect dark matter. Another intriguing and rather novel subject that was discussed at the meeting was time variation of fundamental physical constants. Two speakers have examined the sensitivity of Big-Bang Nucleosynthesis to the variation of the values of the fundamental constants. The role of some specific nuclei (such as Ni 56) in cosmology was pointed out. Many of the presentations at the conference described experimental studies of reactions relevant to nucleosynthesis at various stages of cosmic evolution. As reflected in the conference, these activities are widespread, encompassing many laboratories. Rare Isotope Beam (RIB) facilities are in the forefront of these studies. To understand the various processes of nucleosynthesis one has to have a good theory of nuclei far from the stability line. A number of presentations dealt with the description of such exotic nuclei. It is clear from the presentations that the future of experimental nuclear astrophysics looks promising as existing experimental facilities are being upgraded and new facilities are being built. X-Ray and Gamma-Ray Bursts and cosmic explosions were the subject of several talks. A discussion of various experiments attempting to measure time-reversal violation was the subject of one lecture. The solution of the puzzle as to why the universe is asymmetric with respect to matter-antimatter requires knowledge of the limit of time-reversal conservation. The late John Bahcall was a great astrophysicist and a supporter of the conference series 'Nuclear physics in Astrophysics'. On the last day of the conference, following a talk by Neta Bahcall from Princeton University on dark matter in the Universe, a short commemoration for John was held. Detailed information about the NPA5 conference and its scientific program can be found at: www.weizmann.ac.il/conferences/NPA5/ Naftali Auerbach Michael Hass Michael Paul Editors Conference photograph Conference photograph The PDF also contains lists of the committees and participants.

  7. Does service integration improve technical quality of care in low-resource settings? An evaluation of a model integrating HIV care into family planning services in Kenya

    PubMed Central

    Mutemwa, Richard; Mayhew, Susannah H; Warren, Charlotte E; Abuya, Timothy; Ndwiga, Charity; Kivunaga, Jackline

    2017-01-01

    Abstract The aim of this study was to investigate association between HIV and family planning integration and technical quality of care. The study focused on technical quality of client–provider consultation sessions. The cross-sectional study observed 366 client–provider consultation sessions and interviewed 37 health care providers in 12 public health facilities in Kenya. Multilevel random intercept and linear regression models were fitted to the matched data to investigate relationships between service integration and technical quality of care as well as associations between facility-level structural and provider factors and technical quality of care. A sensitivity analysis was performed to test for hidden bias. After adjusting for facility-level structural factors, HIV/family planning integration was found to have significant positive effect on technical quality of the consultation session, with average treatment effect 0.44 (95% CI: 0.63–0.82). Three of the 12 structural factors were significantly positively associated with technical quality of consultation session including: availability of family planning commodities (9.64; 95% CI: 5.07–14.21), adequate infrastructure (5.29; 95% CI: 2.89–7.69) and reagents (1.48; 95% CI: 1.02–1.93). Three of the nine provider factors were significantly positively associated with technical quality of consultation session: appropriate provider clinical knowledge (3.14; 95% CI: 1.92–4.36), job satisfaction (2.02; 95% CI: 1.21–2.83) and supervision (1.01; 95% CI: 0.35–1.68), while workload (−0.88; 95% CI: −1.75 to − 0.01) was negatively associated. Technical quality of the client–provider consultation session was also determined by duration of the consultation and type of clinic visit and appeared to depend on whether the clinic visit occurred early or later in the week. Integration of HIV care into family planning services can improve the technical quality of client–provider consultation sessions as measured by both health facility structural and provider factors. PMID:29194543

  8. Does service integration improve technical quality of care in low-resource settings? An evaluation of a model integrating HIV care into family planning services in Kenya.

    PubMed

    Mutemwa, Richard; Mayhew, Susannah H; Warren, Charlotte E; Abuya, Timothy; Ndwiga, Charity; Kivunaga, Jackline

    2017-11-01

    The aim of this study was to investigate association between HIV and family planning integration and technical quality of care. The study focused on technical quality of client-provider consultation sessions. The cross-sectional study observed 366 client-provider consultation sessions and interviewed 37 health care providers in 12 public health facilities in Kenya. Multilevel random intercept and linear regression models were fitted to the matched data to investigate relationships between service integration and technical quality of care as well as associations between facility-level structural and provider factors and technical quality of care. A sensitivity analysis was performed to test for hidden bias. After adjusting for facility-level structural factors, HIV/family planning integration was found to have significant positive effect on technical quality of the consultation session, with average treatment effect 0.44 (95% CI: 0.63-0.82). Three of the 12 structural factors were significantly positively associated with technical quality of consultation session including: availability of family planning commodities (9.64; 95% CI: 5.07-14.21), adequate infrastructure (5.29; 95% CI: 2.89-7.69) and reagents (1.48; 95% CI: 1.02-1.93). Three of the nine provider factors were significantly positively associated with technical quality of consultation session: appropriate provider clinical knowledge (3.14; 95% CI: 1.92-4.36), job satisfaction (2.02; 95% CI: 1.21-2.83) and supervision (1.01; 95% CI: 0.35-1.68), while workload (-0.88; 95% CI: -1.75 to - 0.01) was negatively associated. Technical quality of the client-provider consultation session was also determined by duration of the consultation and type of clinic visit and appeared to depend on whether the clinic visit occurred early or later in the week. Integration of HIV care into family planning services can improve the technical quality of client-provider consultation sessions as measured by both health facility structural and provider factors. © The Author 2017. Published by Oxford University Press in association with The London School of Hygiene and Tropical Medicine.

  9. Multi-session complex averaging for high resolution high SNR 3T MR visualization of ex vivo hippocampus and insula

    NASA Astrophysics Data System (ADS)

    Stamm, Aymeric; Singh, Jolene M.; Scherrer, Benoit; Afacan, Onur; Warfield, Simon K.

    2015-03-01

    The hippocampus and the insula are responsible for episodic memory formation and retrieval. Hence, visualization of the cytoarchitecture of such structures is of primary importance to understand the underpinnings of conscious experience. Magnetic Resonance Imaging (MRI) offers an opportunity to non-invasively image these crucial structures. However, current clinical MR imaging operates at the millimeter scale while these anatomical landmarks are organized into sub-millimeter structures. For instance, the hippocampus contains several layers, including the CA3-dentate network responsible for encoding events and experiences. To investigate whether memory loss is a result of injury or degradation of CA3/dentate, spatial resolution must exceed one hundred micron, isotropic, voxel size. Going from one millimeter voxels to one hundred micron voxels results in a 1000× signal loss, making the measured signal close to or even way below the precision of the receiving coils. Consequently, the signal magnitude that forms the structural images will be biased and noisy, which results in inaccurate contrast and less than optimal signal-to-noise ratio (SNR). In this paper, we propose a strategy to perform high spatial resolution MR imaging of the hippocampus and insula with 3T scanners that enables accurate contrast (no systematic bias) and arbitrarily high SNR. This requires the collection of additional repeated measurements of the same image and a proper averaging of the k-space data in the complex domain. This comes at the cost of additional scan time, but long single-session scan times are not practical for obvious reasons. Hence, we also develop an approach to combine k-space data from multiple sessions, which enables the total scan time to be split into arbitrarily short sessions, where the patient is allowed to move and rest in-between. For validation, we hereby illustrate our multi-session complex averaging strategy by providing high spatial resolution 3T MR visualization of the hippocampus and insula using an ex-vivo specimen, so that the number of sessions and the duration of each session are not limited by physiological motion or poor subject compliance.

  10. Current and Future Applications of Mechanical Fasteners for Light-Frame Wood Structures: Proceedings of Mechanical Fasteners Plenary Session at the Forest Products Research Society Annual Meeting

    Treesearch

    Leslie H. Groom; [Compiler

    1993-01-01

    The title of this publication-"Current and Future Applications of Mechanical Fasteners for Light-Frame Wood Structures" is the theme of this plenary session from the 1991 annual meeting of the Forest Products Research Society (FPRS). This theme was chosen to address current issues in the forest products industry: changing design codes, fastener performance,...

  11. Home-based teaching: what are we asking of parents?

    PubMed

    McConachie, H R

    1991-01-01

    Professional services for young children with disabilities generally expect parents (usually mothers) to carry out teaching or therapy exercises at home. Their advice often implies structuring the work into special daily sessions. In this study, parents were asked to carry out play sessions, and managed 62% of the available days. Reasons for missing sessions were primarily shortage of time or child illness. Mothers were more likely to carry out sessions where their child was of lower ability, and fathers less likely. Discussion concentrates on the need for professionals to vary their expectations and approach with individual parents' philosophies and energies.

  12. Role for Tyrosine Phosphorylation of A-kinase Anchoring Protein 8 (AKAP8) in Its Dissociation from Chromatin and the Nuclear Matrix.

    PubMed

    Kubota, Sho; Morii, Mariko; Yuki, Ryuzaburo; Yamaguchi, Noritaka; Yamaguchi, Hiromi; Aoyama, Kazumasa; Kuga, Takahisa; Tomonaga, Takeshi; Yamaguchi, Naoto

    2015-04-24

    Protein-tyrosine phosphorylation regulates a wide variety of cellular processes at the plasma membrane. Recently, we showed that nuclear tyrosine kinases induce global nuclear structure changes, which we called chromatin structural changes. However, the mechanisms are not fully understood. In this study we identify protein kinase A anchoring protein 8 (AKAP8/AKAP95), which associates with chromatin and the nuclear matrix, as a nuclear tyrosine-phosphorylated protein. Tyrosine phosphorylation of AKAP8 is induced by several tyrosine kinases, such as Src, Fyn, and c-Abl but not Syk. Nucleus-targeted Lyn and c-Src strongly dissociate AKAP8 from chromatin and the nuclear matrix in a kinase activity-dependent manner. The levels of tyrosine phosphorylation of AKAP8 are decreased by substitution of multiple tyrosine residues on AKAP8 into phenylalanine. Importantly, the phenylalanine mutations of AKAP8 inhibit its dissociation from nuclear structures, suggesting that the association/dissociation of AKAP8 with/from nuclear structures is regulated by its tyrosine phosphorylation. Furthermore, the phenylalanine mutations of AKAP8 suppress the levels of nuclear tyrosine kinase-induced chromatin structural changes. In contrast, AKAP8 knockdown increases the levels of chromatin structural changes. Intriguingly, stimulation with hydrogen peroxide induces chromatin structural changes accompanied by the dissociation of AKAP8 from nuclear structures. These results suggest that AKAP8 is involved in the regulation of chromatin structural changes through nuclear tyrosine phosphorylation. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  13. Co-ordination of the International Network of Nuclear Structure and Decay Data Evaluators; Summary Report of an IAEA Technical Meeting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Abriola, D.; Tuli, J.

    The IAEA Nuclear Data Section convened the 18th meeting of the International Network of Nuclear Structure and Decay Data Evaluators at the IAEA Headquarters, Vienna, 23 to 27 March 2009. This meeting was attended by 22 scientists from 14 Member States, plus IAEA staff, concerned with the compilation, evaluation and dissemination of nuclear structure and decay data. A summary of the meeting, recommendations/conclusions, data centre reports, and various proposals considered, modified and agreed by the participants are contained within this document. The International Network of Nuclear Structure and Decay Data (NSDD) Evaluators holds biennial meetings under the auspices of themore » IAEA, and consists of evaluation groups and data service centres in several countries. This network has the objective of providing up-to-date nuclear structure and decay data for all known nuclides by evaluating all existing experimental data. Data resulting from this international evaluation collaboration is included in the Evaluated Nuclear Structure Data File (ENSDF) and published in the journals Nuclear Physics A and Nuclear Data Sheets (NDS).« less

  14. Turbine Engine Hot Section Technology, 1984

    NASA Technical Reports Server (NTRS)

    1984-01-01

    Presentations were made concerning the hot section environment and behavior of combustion liners, turbine blades, and waves. The presentations were divided into six sessions: instrumentation, combustion, turbine heat transfer, structural analysis, fatigue and fracture, and surface properties. The principal objective of each session was to disseminate research results to date, along with future plans. Topics discussed included modeling of thermal and fluid flow phenomena, structural analysis, fatigue and fracture, surface protective coatings, constitutive behavior, stress-strain response, and life prediction methods.

  15. The influence of a yoga exercise program for young adults with intellectual disabilities.

    PubMed

    Hawkins, Brent L; Stegall, Joanna B; Weber, Madalyn F; Ryan, Joseph B

    2012-07-01

    Individuals with intellectual disabilities (ID) have an increased risk of obesity and are significantly less likely to engage in physical activity compared to their nondisabled peers. A growing body of research supports the physical and mental health benefits of yoga. While the benefits of yoga have been studied across a host of populations with varying ages and physical disabilities, no studies could be identified investigating the benefits of yoga for young adults with ID. This study investigated the impact of participating in yoga classes on the amount of exercise behavior and perception of physical exertion when compared to non-structured exercise sessions between two young adults with ID in a post-secondary education setting. A single subject multiple baseline research design was implemented across two young adults with mild ID to determine the effects of a yoga exercise class on frequency of exercise behavior and perception of physical exertion when compared to non-structured exercise sessions. Partial interval recording, the Eston-Parfitt curvilinear rating of perceived exertion scale, and the physical activity enjoyment scale were implemented to collect data on dependent variables and consumer satisfaction during each non-structured exercise session and each yoga class. indicated that percentage of exercise behavior and perceived exertion levels during yoga group exercise sharply increased with large effect sizes when compared to non-structured exercise sessions.

  16. Strategies for the Internal Development of Summer Sessions.

    ERIC Educational Resources Information Center

    Seagren, Alan T.; And Others

    Organizational matters and strategies useful in developing more effective collegiate summer sessions are discussed, and examples of some productive strategies at the University of Nebraska-Lincoln are reported. Four elements of organizational structure in higher education considered are organizational environment, mission and goals, governance…

  17. PREFACE: International Conference on Structural Nano Composites (NANOSTRUC 2012)

    NASA Astrophysics Data System (ADS)

    Njuguna, James

    2012-09-01

    Dear Colleagues It is a great pleasure to welcome you to NanoStruc2012 at Cranfield University. The purpose of the 2012 International Conference on Structural Nano Composites (NanoStruc2012) is to promote activities in various areas of materials and structures by providing a forum for exchange of ideas, presentation of technical achievements and discussion of future directions. NanoStruc brings together an international community of experts to discuss the state-of-the-art, new research results, perspectives of future developments, and innovative applications relevant to structural materials, engineering structures, nanocomposites, modelling and simulations, and their related application areas. The conference is split in 7 panel sessions, Metallic Nanocomposites and Coatings, Silica based Nanocomposites, safty of Nanomaterials, Carboin based Nanocomposites, Multscale Modelling, Bio materials and Application of Nanomaterials. All accepted Papers will be published in the IOP Conference Series: Materials Science and Engineering (MSE), and included in the NanoStruc online digital library. The abstracts will be indexed in Scopus, Compedex, Inspec, INIS (International Nuclear Information System), Chemical Abstracts, NASA Astrophysics Data System and Polymer Library. Before ending this message, I would like to acknowledge the hard work, professional skills and efficiency of the team which ensured the general organisation. As a conclusion, I would like to Welcome you to the Nanostruc2012 and wish you a stimulating Conference and a wonderful time. On behalf of the scientific committee, Signature James Njuguna Conference Chair The PDF of this preface also contains committee listings and associates logos.

  18. Integration of Lower Level Supervisors into the Management Structure.

    DTIC Science & Technology

    1981-08-31

    sessions. Brief (2-3 hour) training "work sessions" could be developed to help lower level supervisors 4 solve specific problema . These sessions...34 In D. Cartwright (ed.), Studies in Social Power. Ann Arbor, MI: The University of Michigan Press, 1959. Gardner, B.B. & Whyte, W.F. "The man in the...line supervisory problem redefined." Personnel Journal, 1975, 54(12), 620-623+. Stouffer, S.A. "An analysis of conflicting social norms." American

  19. Neurophysiological correlates of eye movement desensitization and reprocessing sessions: preliminary evidence for traumatic memories integration.

    PubMed

    Farina, Benedetto; Imperatori, Claudio; Quintiliani, Maria I; Castelli Gattinara, Paola; Onofri, Antonio; Lepore, Marta; Brunetti, Riccardo; Losurdo, Anna; Testani, Elisa; Della Marca, Giacomo

    2015-11-01

    We have investigated the potential role of eye movement desensitization and reprocessing (EMDR) in enhancing the integration of traumatic memories by measuring EEG coherence, power spectra and autonomic variables before (pre-EMDR) and after (post-EMDR) EMDR sessions during the recall of patient's traumatic memory. Thirteen EMDR sessions of six patients with post-traumatic stress disorder were recorded. EEG analyses were conducted by means of the standardized Low Resolution Electric Tomography (sLORETA) software. Power spectra, EEG coherence and heart rate variability (HRV) were compared between pre- and post-EMDR sessions. After EMDR, we observed a significant increase of alpha power in the left inferior temporal gyrus (T = 3.879; P = 0.041) and an increased EEG coherence in beta band between C3 and T5 electrodes (T = 6.358; P < 0.001). Furthermore, a significant increase of HRV in the post-EMDR sessions was also observed (pre-EMDR: 6.38 ± 6.83; post-EMDR: 2.46 ± 2.95; U-Test = 45, P = 0.043). Finally, the values of lagged coherence were negatively associated with subjective units of disturbance (r(24) = -0.44, P < 0.05) and positively associated with parasympathetic activity (r(24) = 0.40, P < 0.05). Our results suggest that EMDR leads to an integration of dissociated aspects of traumatic memories and, consequently, a decrease of hyperarousal symptoms [Correction made here after initial publication]. © 2014 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  20. Effects of active recovery on autonomic and haemodynamic responses after aerobic exercise.

    PubMed

    Soares, Antonio H G; Oliveira, Tiago P; Cavalcante, Bruno R; Farah, Breno Q; Lima, Aluísio H R A; Cucato, Gabriel G; Cardoso, Crivaldo G; Ritti-Dias, Raphael M

    2017-01-01

    The aim of this study was to examine the effect of active recovery on autonomic and haemodynamic responses after exercise in healthy adults. Nineteen healthy young male individuals underwent two experimental sessions: exercise with active recovery (AR) and exercise with passive recovery (PR). The exercise sessions comprised three phases: warm-up (5 min), exercise phase (cycle ergometer, 30 min, intensity between 60 and 70% of the heart rate reserve) and recovery (5 min). In the AR, the subjects remained cycling in the recovery phase at intensity between 30% and 35% of heart rate reserve, while in the PR, the subjects stopped the exercise after finishing the exercise phase. Blood pressure and heart rate were measured before and over the 30 min after the interventions. There were no differences for systolic and diastolic blood pressures, heart rate and rate pressure product between active and passive recovery sessions. Also, all heart rate variability parameters changed similarly after exercise with passive or active recovery sessions. In summary, exercise with active recovery does not affect the autonomic and haemodynamic responses after moderate-intensity aerobic exercise in healthy young male individuals. © 2015 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  1. Training and Support of Sessional Staff to Improve Quality of Teaching and Learning at Universities.

    PubMed

    Knott, Gillian; Crane, Linda; Heslop, Ian; Glass, Beverley D

    2015-06-25

    Sessional staff is increasingly involved in teaching at universities, playing a pivotal role in bridging the gap between theory and practice for students, especially in the health professions, including pharmacy. Although sessional staff numbers have increased substantially in recent years, limited attention has been paid to the quality of teaching and learning provided by this group. This review will discuss the training and support of sessional staff, with a focus on Australian universities, including the reasons for and potential benefits of training, and structure and content of training programs. Although sessional staff views these programs as valuable, there is a lack of in-depth evaluations of the outcomes of the programs for sessional staff, students and the university. Quality assurance of such programs is only guaranteed, however, if these evaluations extend to the impact of this training and support on student learning.

  2. Fifth international fungus spore conference

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Timberlake, W.E.

    1993-04-01

    This folio contains the proceedings of the Fifth International Fungal Spore Conference held August 17-21, 1991 at the Unicoi State Park at Helen, Georgia. The volume contains abstracts of each oral presentation as well as a collection of abstracts describing the poster sessions. Presentations were organized around the themes (1) Induction of Sporulation, (2) Nuclear Division, (3) Spore Formation, (4) Spore Release and Dispersal, and (4) Spore Germination.

  3. America's Energy Potential: A Summary and Explanation; Committee on Interior and Insular Affairs, U.S. House of Representatives, Ninety-Third Congress, First Session. [Committee Print].

    ERIC Educational Resources Information Center

    Udall, Morris K.

    This report reviews America's current energy position. The energy sources studied include oil and gas, coal, nuclear energy, solar energy, and geothermal energy. Each source is analyzed in terms of current use, technology for extracting and developing the energy, research and development funding, and projections for future consumption and…

  4. Energy Facts; Subcommittee on Energy of the Committee on Science and Astronautics, House of Representatives, Ninety-Third Congress, First Session [Committee Print.

    ERIC Educational Resources Information Center

    Library of Congress, Washington, DC. Congressional Research Service.

    This handbook contains a comprehensive selection of United States and foreign energy statistics in the form of graphs and tables. The data are classified according to resources, production, consumption and demand, energy and gross national product, and research and development. Statistics on energy sources such as coal, oil, gas, nuclear energy,…

  5. Three-dimensional sinus imaging as an adjunct to two-dimensional imaging to accelerate education and improve spatial orientation.

    PubMed

    Yao, William C; Regone, Rachel M; Huyhn, Nancy; Butler, E Brian; Takashima, Masayoshi

    2014-03-01

    Develop a novel three-dimensional (3-D) anatomical model to assist in improving spatial knowledge of the skull base, paranasal sinuses, and adjacent structures, and validate the utilization of 3-D reconstruction to augment two-dimensional (2-D) computed tomography (CT) for the training of medical students and otolaryngology-head and neck surgery residents. Prospective study. A study of 18 subjects studying sinus anatomy was conducted at a tertiary academic center during the 2011 to 2012 academic year. An image processing and 3-D modeling program was used to create a color coded 3-D scalable/layerable/rotatable model of key paranasal and skull base structures from a 2-D high-resolution sinus CT scan. Subjects received instruction of the sinus anatomy in two sessions, first through review of a 2-D CT sinus scan, followed by an educational module of the 3-D reconstruction. After each session, subjects rated their knowledge of the sinus and adjacent structures on a self-assessment questionnaire. Significant improvement in the perceived understanding of the anatomy was noted after the 3-D educational module session when compared to the 2-D CT session alone (P < .01). Every subject believed the addition of 3-D imaging accelerated their education of sinus anatomy and recommended its use to others. The impression of the learners was that a 3-D educational module, highlighting key structures, is a highly effective tool to enhance the education of medical students and otolaryngology residents in sinus and skull base anatomy and its adjacent structures, specifically in conceptualizing the spatial orientation of these structures. © 2013 The American Laryngological, Rhinological and Otological Society, Inc.

  6. Proceedings of the Seventh International Conference on Mars

    NASA Technical Reports Server (NTRS)

    2007-01-01

    The oral and poster sessions of the SEVENTH INTERNATIONAL CONFERENCE ON MARS included; The Distribution and Context of Water-related Minerals on Mars; Poster Session: Mars Geology; Geology of the Martian Surface: Lithologic Variation, Composition, and Structure; Water Through Mars' Geologic History; Poster Session: Mars Water and the Martian Interior; Volatiles and Interior Evolution; The Martian Climate and Atmosphere: Variations in Time and Space; Poster Session: The Martian Climate and Current Processes; Modern Mars: Weather, Atmospheric Chemistry, Geologic Processes, and Water Cycle; Public Lecture: Mars Reconnaissance Orbiter's New View of the Red Planet; The North and South Polar Layered Deposits, Circumpolar Regions, and Changes with Time; Poster Session: Mars Polar Science, Astrobiology, Future Missions/Instruments, and Other Mars Science; Mars Astrobiology and Upcoming Missions; and Martian Stratigraphy and Sedimentology: Reading the Sedimentary Record.

  7. Report for 2011 from the Bordeaux IVS Analysis Center

    NASA Technical Reports Server (NTRS)

    Charlot, Patrick; Bellanger, Antoine; Bourda, Geraldine; Collioud, Arnaud; Baudry, Alain

    2012-01-01

    This report summarizes the activities of the Bordeaux IVS Analysis Center during the year 2011. The work focused on (i) regular analysis of the IVS-R1 and IVS-R4 sessions with the GINS software package; (ii) systematic VLBI imaging of the RDV sessions and calculation of the corresponding source structure index and compactness values; (iii) imaging of the sources observed during the 2009 International Year of Astronomy IVS observing session; and (iv) continuation of our VLBI observational program to identify optically-bright radio sources suitable for the link with the future Gaia frame. Also of importance is the enhancement of the IVS LiveWeb site which now comprises all IVS sessions back to 2003, allowing one to search past observations for session-specific information (e.g. sources or stations).

  8. Belief Structures of Students For and Against the Nuclear Freeze.

    ERIC Educational Resources Information Center

    Tankard, James W., Jr.

    An investigation of college students' belief structures underlying their support or non-support of a nuclear freeze revealed a three-dimensional structure for beliefs in the areas of nuclear weapons and national defense. A questionnaire containing 25 belief statements concerning national defense and nuclear weapons and 4 media use questions was…

  9. Nuclear Data Sheets page at the NNDC

    Science.gov Websites

    Data Sheets is a journal primarily devoted to the publication of evaluated nuclear structure and decay ; neutron, proton, alpha, cluster and cluster emission; fission. Nuclear structure and decay data are basis. The ENSDF database is the source for the nuclear structure and decay articles, which deal with a

  10. Multi-modality imaging: Bird's eye view from the 2017 American Heart Association Scientific Sessions.

    PubMed

    AlJaroudi, Wael A; Lloyd, Steven G; Hage, Fadi G

    2018-04-01

    This review summarizes key imaging studies that were presented in the American Heart Association Scientific Sessions 2017 related to the fields of nuclear cardiology, cardiac computed tomography, cardiac magnetic resonance, and echocardiography. The aim of this bird's eye view is to inform readers about multiple studies reported at the meeting from these different imaging modalities. While such a review is most useful for those that did not attend the conference, we find that a general overview may also be useful to those that did since it is often difficult to get exposure to many abstracts at large meetings. The review, therefore, aims to help readers stay updated on the newest imaging studies presented at the meeting and will hopefully stimulate new ideas for future research in imaging.

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dillon, C.

    Over the past few years, numerous Accreditation Bodies, Regulatory Agencies, and State Regulations have implemented requirements for Radiation Safety Surveys following installation or modification to x-ray rooms. The objective of this session is to review best practices in performing radiation safety surveys for both Therapy and Diagnostic installations, as well as a review of appropriate survey instruments. This session will be appropriate for both therapy and imaging physicists who are looking to increase their working knowledge of radiation safety surveys. Learning Objectives: Identify Appropriate Survey Meters for Radiation Safety Surveys Develop best practices for Radiation Safety Surveys for Therapy unitsmore » that include common areas of concern. Develop best practices for Radiation Safety Surveys of Diagnostic and Nuclear Medicine rooms. Identify acceptable dose levels and the factors that affect the calculations associated with performing Radiation Safety Surveys.« less

  12. Proceedings of the Third International Workshop on the implementation of ALARA at nuclear power plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Khan, T.A.; Roecklein, A.K.

    1995-03-01

    This report contains the papers presented and the discussions that took place at the Third International Workshop on ALARA Implementation at Nuclear Power Plants, held in Hauppauge, Long Island, New York from May 8--11, 1994. The purpose of the workshop was to bring together scientists, engineers, health physicists, regulators, managers and other persons who are involved with occupational dose control and ALARA issues. The countries represented were: Canada, Finland, France, Germany, Japan, Korea, Mexico, the Netherlands, Spain, Sweden, the United Kingdom and the United States. The workshop was organized into twelve sessions and three panel discussions. Individual papers have beenmore » cataloged separately.« less

  13. Introduction to special session on "ultrasonic transducers for harsh environments

    NASA Astrophysics Data System (ADS)

    Tittmann, B. R.; Reinhardt, B.; Daw, J.

    2018-04-01

    This work describes the results of experiments conducted as part of an instrumented lead test in-core in a nuclear reactor with the piezoelectric and magnetostrictive materials. The experiments exposed AlN, ZnO, BiT, Remendur, and Galfenol to more neutron radiation than found in the literature. The magnetostrictive sensors produce stable ultrasonic pulse-echoes throughout much of the irradiation. The BiT transducers could operate up until approximate 5 × 10^20 n/cm^2 (E>1MeV). The piezoelectric AlN operated well during the entire experiment. The results imply that now available are candidates for operation in harsh environments found in nuclear reactors and steam generator plants.

  14. The Conference Proceedings of the 1998 Air Transport Research Group (ATRG) of the WCTR Society. Volume 1

    NASA Technical Reports Server (NTRS)

    Oum, Tae Hoon (Editor); Bowen, Brent D. (Editor)

    1998-01-01

    This report (Volume 1) is comprised of 5 sessions of the Air Transport Research Group (ATRG) Conference held in Antwerp, Belgium, July 1998. The sessions contain 3-4 papers (presentations) each. The session numbers and their respective headings are: (1) Airline alliances; (2) Airline Competition and Market Structure; (4) Liberalization, Open Skies, and Policy Issues; (5) Yield Management and Other Models; and (11) Air Traffic Control (ATC) and Air Navigational Systems (ANS).

  15. Orientation Tactics Utilized in Postprofessional Athletic Training Programs

    ERIC Educational Resources Information Center

    Walker, Stacy E.; Mazerolle, Stephanie M.; Thrasher, Ashley B.

    2016-01-01

    Context: Some newly credentialed athletic trainers pursue a postprofessional degree with a curriculum that specifically advances their athletic training practice. Orientation sessions are a tactic used to assist these students' transition into these new roles of graduate student and independent clinician, yet the structure of these sessions is…

  16. Attitudes of Healthcare Students on Gross Anatomy Laboratory Sessions

    ERIC Educational Resources Information Center

    Kawashiro, Yukiko; Anahara, Reiko; Kohno, Toshihiko; Mori, Chisato; Matsuno, Yoshiharu

    2009-01-01

    At Chiba University, gross anatomy laboratory sessions ("laboratories") are required for physical therapy students. Though most physical therapy schools require their students to participate in laboratories so that they will better understand the structure of the human body, few data exist on the value of these laboratories specifically…

  17. Proceedings of the XXI International Workshop High Energy Physics and Quantum Field Theory (QFTHEP 2013). 23 30 June, 2013. Saint Petersburg Area, Russia

    NASA Astrophysics Data System (ADS)

    The Workshop continues a series of workshops started by the Skobeltsyn Institute of Nuclear Physics of Lomonosov Moscow State University (SINP MSU) in 1985 and conceived with the purpose of presenting topics of current interest and providing a stimulating environment for scientific discussion on new developments in theoretical and experimental high energy physics and physical programs for future colliders. Traditionally the list of workshop attendees includes a great number of active young scientists and students from Russia and other countries. This year the Workshop is organized jointly by the SINP MSU and the SPbSU and it will take place in the holiday hotel "Baltiets" situated in a picturesque place of the Karelian Isthmus on the shore of the Gulf of Finland in the suburb of the second largest Russian city Saint Petersburg. Scientific program, the main topics to be covered are: * Higgs searches and other experimental results from the LHC and the Tevatron; impact of the Higgs-like boson observed * Physics prospects at Linear Colliders and super B-factories * Extensions of the Standard Model and their phenomenological consequences at the LHC and Linear Colliders * Higher order corrections and resummations for collider phenomenology * Automatic calculations and Monte Carlo simulations in high energy physics * LHC/LC and astroparticle/cosmology connections * Modern nuclear physics and relativistic nucleous-nucleous collisions * Detectors for future experiments in high energy physics The Workshop will include plenary and two parallel afternoon sessions. The plenary sessions will consist of invited lectures. The afternoon sessions will include original talks. Further details are given at http://qfthep.sinp.msu.ru

  18. Empirical evidence of the effectiveness of concept mapping as a learning intervention for nuclear medicine technology students in a distance learning radiation protection and biology course.

    PubMed

    Passmore, Gregory G; Owen, Mary Anne; Prabakaran, Krishnan

    2011-12-01

    Metacognitive learning strategies are based on instructional learning theory, which promotes deep, meaningful learning. Educators in a baccalaureate-level nuclear medicine technology program demonstrated that students enrolled in an online, distance learning section of an introductory radiation protection and radiobiology course performed better when traditional instruction was supplemented with nontraditional metacognitive learning strategies. The metacognitive learning strategy that was used is best known as concept mapping. The concept map, in addition to the standard homework problem assignment and opportunity for question-answer sessions, became the template for misconception identification and remediation interactions between the instructor and the student. The control group relied on traditional homework problems and question-answer sessions alone. Because students in both the "treatment" groups (i.e., students who used concept mapping) and the control group were distance learning students, all personal communications were conducted via e-mail or telephone. The final examination of the course was used to facilitate a quantitative comparison of the performance of students who used concept mapping and the performance of students who did not use concept mapping. The results demonstrated a significantly higher median final examination score for the concept mapping group than for the non-concept mapping group (z = -2.0381, P = 0.0415), with an appropriately large effect size (2.65). Concept mapping is a cognitive learning intervention that effectively enables meaningful learning and is suitable for use in the independent learner-oriented distance learning environments used by some nuclear medicine technology programs.

  19. Production of an English/Russian glossary of terminology for nuclear materials control and accounting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schachowskoj, S.; Smith, H.A. Jr.

    The program plans for Former Soviet Union National Nuclear Materials Control and Accounting (MC and A) Systems Enhancements call for the development of an English/Russian Glossary of MC and A terminology. This glossary was envisioned as an outgrowth of the many interactions, training sessions, and other talking and writing exercises that would transpire in the course of carrying out these programs. This report summarizes the status of the production of this glossary, the most recent copy of which is attached to this report. The glossary contains over 950 terms and acronyms associated with nuclear material control and accounting for safeguardsmore » and nonproliferation. This document is organized as follows: English/Russian glossary of terms and acronyms; Russian/English glossary of terms and acronyms; English/Russian glossary of acronyms; and Russian/English glossary of acronyms.« less

  20. DNDO Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liegey, Lauren Rene; Wilcox, Trevor; Mckinney, Gregg Walter

    2015-08-07

    My internship program was the Domestic Nuclear Detection Office Summer Internship Program. I worked at Los Alamos National Laboratory with Trevor A. Wilcox and Gregg W. McKinney in the NEN-5 group. My project title was “MCNP Physical Model Interoperability & Validation”. The goal of my project was to write a program to predict the solar modulation parameter for dates in the future and then implement it into MCNP6. This update to MCNP6 can be used to calculate the background more precisely, which is an important factor in being able to detect Special Nuclear Material. We will share our work inmore » a published American Nuclear Society (ANS) paper, an ANS presentation, and a LANL student poster session. Through this project, I gained skills in programming, computing, and using MCNP. I also gained experience that will help me decide on a career or perhaps obtain employment in the future.« less

  1. Development of a gastroenterology educational curriculum for pediatric residents using fellows as teachers.

    PubMed

    Pentiuk, Scott; Baker, Raymond

    2012-02-01

    At many institutions, the teaching provided on subspecialty gastroenterology rotations is not structured. The purpose of the present study was to describe the development, implementation, and assessment of a structured gastroenterology curriculum for pediatric residents. A needs assessment was performed via a survey of former pediatric resident graduates presently working in general pediatrics. Topics for the curriculum were developed based upon the needs assessment. Second-year residents on the inpatient gastroenterology rotation attended 4 case-based, small group sessions per week for 1 month. Sessions were taught primarily by upper-level gastroenterology fellows. The curriculum was assessed via a pre-posttest, postrotation survey, and group feedback sessions. Resident rating of education received during the rotation was high. Posttest scores increased slightly but significantly compared with pretest values. The curriculum has continued to be used >4 years after its development. The creation of a structured subspecialty curriculum with the use of fellows as teachers is both feasible and effective despite limitations in available time for resident teaching.

  2. Nuclear Structure Aspects in Nuclear Astrophysics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Smith, Michael Scott

    2006-12-01

    Nuclear Astrophysics as a broad and diverse field of study can be viewed as a magnifier of the impact of microscopic processes on the evolution of macroscopic events. One of the primary goals in Nuclear Astrophysics is the understanding of the nucleosynthesis processes that take place in the cosmos and the simulation of the correlated stellar and explosive burning scenarios. These simulations are strongly dependent on the input from Nuclear Physics which sets the time scale for all stellar dynamic processes--from giga-years of stellar evolution to milliseconds of stellar explosions--and provides the basis for most of the signatures that wemore » have for the interpretation of these events--from stellar luminosities, elemental and isotopic abundances to neutrino flux from distant supernovae. The Nuclear Physics input comes through nuclear structure, low energy reaction rates, nuclear masses, and decay rates. There is a common perception that low energy reaction rates are the most important component of the required nuclear physics input; however, in this article we take a broader approach and present an overview of the close correlation between various nuclear structure aspects and their impact on nuclear astrophysics. We discuss the interplay between the weak and the strong forces on stellar time scales due to the limitations they provide for the evolution of slow and rapid burning processes. The effects of shell structure in nuclei on stellar burning processes as well as the impact of clustering in nuclei is outlined. Furthermore we illustrate the effects of the various nuclear structure aspects on the major nucleosynthesis processes that have been identified in the last few decades. We summarize and provide a coherent overview of the impact of all aspects of nuclear structure on nuclear astrophysics.« less

  3. PREFACE: Quark Matter 2006 Conference

    NASA Astrophysics Data System (ADS)

    Ma, Yu-Gang; Wang, En-Ke; Cai, Xu; Huang, Huan-Zhong; Wang, Xin-Nian; Zhu, Zhi-Yuan

    2007-07-01

    The Quark Matter 2006 conference was held on 14 20 November 2006 at the Shanghai Science Hall of the Shanghai Association of Sciences and Technology in Shanghai, China. It was the 19th International Conference on Ultra-Relativistic Nucleus Nucleus Collisions. The conference was organized jointly by SINAP (Shanghai Institute of Applied Physics, Chinese Academy of Sciences (CAS)) and CCNU (Central China Normal University, Wuhan). Over 600 scientists from 32 countries in five continents attended the conference. This is the first time that China has hosted such a premier conference in the field of relativistic heavy-ion collisions, an important event for the Chinese high energy nuclear physics community. About one half of the conference participants are junior scientists—a clear indication of the vigor and momentum for this field, in search of the fundamental nature of the nuclear matter at extreme conditions. Professor T D Lee, honorary chair of the conference and one of the founders of the quark matter research, delivered an opening address with his profound and philosophical remarks on the recent discovery of the nature of strongly-interacting quark-gluon-plasma (sQGP). Professor Hongjie Xu, director of SINAP, gave a welcome address to all participants on behalf of the two hosting institutions. Dr Peiwen Ji, deputy director of the Mathematics and Physics Division of the Natural Science Foundation of China (NSFC), also addressed the conference participants and congratulated them on the opening of the conference. Professor Mianheng Jiang, vice president of the Chinese Academy of Sciences (CAS), gave a concise introduction about the CAS as the premier research institution in China. He highlighted continued efforts at CAS to foster international collaborations between China and other nations. The Quark Matter 2006 conference is an example of such a successful collaboration between high energy nuclear physicists in China and other nations all over the world. The scientific program of the conference began with an overview of high energy nuclear physics in China by Professor Wenqing Shen, vice president of the National Natural Science Foundation of China. Professor Shen highlighted many contributions made by the Chinese scientists in both theory and experiment. Dr Nick Samios, former director of Brookhaven National Laboratory (BNL), gave a vivid account of the early years of RHIC and recent accomplishments. Highlights of the conference include new results from RHIC at BNL and SPS (Super Proton Synchrotron) at CERN (European Organization for Nuclear Research). Many experimental results reported at the conference support the notion that the quark-gluon matter at RHIC behaves like a perfect liquid with minimum viscosity to entropy ratio. There were 15 plenary sessions which covered 54 plenary talks, 12 parallel sessions and 1 poster session. A total of 320 abstracts were submitted to the conference out of which 124 were selected for oral presentation and the rest were assigned to the poster session. Talks and posters in the conference covered a broad range of experimental and theoretical progress in ultra-relativistic heavy-ion collisions, which includes new evidence of sQGP, jet quenching and heavy quark energy loss, heavy-ion collision phenomenology, quantum field theory at finite temperature and/or density, and relevant areas of astrophysics and plasma physics. The Quark Matter 2006 conference coincided with the 80th birthday of Professor T D Lee. A special reception was held in the banquet hall of the Shanghai Grand Theatre to celebrate Professor Lee's birthday and to honor his great contributions to physics, in particular, to the development of high energy nuclear physics research in China. We would like to thank the members of the International Advisory Committee for providing valuable advice on a variety of matters, from the general structure of the conference to the selection of the plenary speakers and selection of abstracts for oral presentations. Professors T Hemmick, H Satz, D T Son and N Xu gave excellent pedagogical lectures in the pre-conference student symposium and their efforts were greatly appreciated. The Shanghai Association of Science and Technology (SAST) and the staff of the Shanghai science hall provided valuable assistance and services during the conference. The conference would not have run so smoothly without their professional dedication. We also thank Professor Wenqing Shen, Chairman of the SAST, for his many valuable suggestions to the conference organizers and for providing close cooperation with SAST staff. We thank members of the Local Organizing Committee for many useful suggestions and help. We would like to express our special appreciation for the tireless efforts by many local staff who worked very hard to make this conference a success. Dr Xiang-Zhou Cai, Mrs Wei Zhou and Mrs Yang Shen undertook many duties to coordinate and organize the local services. Dr Kun Wang took responsibility of the conference web page. Dr Wei Guo, Dr Wendong Tian, Mr Chunwang Ma and Mrs Wanyan Qian organized student volunteers for the conference. Without their help and dedication this conference could not have been such a success. The Quark Matter 2006 conference has received substantial financial support from many organizations, including the Chinese Academy of Sciences (CAS), the National Natural Science Foundation of China (NSFC), the Ministry of Education of China (MOE), Shanghai Science and Technology Committee (SSTC), Chinese Nuclear Physics Society (CNPS), Shanghai Institute of Applied Physics (SINAP), Central China Normal University (CCNU), China Center of Advanced Science and Technology (CCAST), Brookhaven National Laboratory (BNL), Lawrence Berkeley National Laboratory (LBNL), European Laboratory for Particle Physics (CERN), and Journal of Physics G: Nuclear and Particle Physics (IOP Publishing).

  4. Visualizing the molecular sociology at the HeLa cell nuclear periphery.

    PubMed

    Mahamid, Julia; Pfeffer, Stefan; Schaffer, Miroslava; Villa, Elizabeth; Danev, Radostin; Cuellar, Luis Kuhn; Förster, Friedrich; Hyman, Anthony A; Plitzko, Jürgen M; Baumeister, Wolfgang

    2016-02-26

    The molecular organization of eukaryotic nuclear volumes remains largely unexplored. Here we combined recent developments in cryo-electron tomography (cryo-ET) to produce three-dimensional snapshots of the HeLa cell nuclear periphery. Subtomogram averaging and classification of ribosomes revealed the native structure and organization of the cytoplasmic translation machinery. Analysis of a large dynamic structure-the nuclear pore complex-revealed variations detectable at the level of individual complexes. Cryo-ET was used to visualize previously elusive structures, such as nucleosome chains and the filaments of the nuclear lamina, in situ. Elucidation of the lamina structure provides insight into its contribution to metazoan nuclear stiffness. Copyright © 2016, American Association for the Advancement of Science.

  5. The controversial nuclear matrix: a balanced point of view.

    PubMed

    Martelli, A M; Falcieri, E; Zweyer, M; Bortul, R; Tabellini, G; Cappellini, A; Cocco, L; Manzoli, L

    2002-10-01

    The nuclear matrix is defined as the residual framework after the removal of the nuclear envelope, chromatin, and soluble components by sequential extractions. According to several investigators the nuclear matrix provides the structural basis for intranuclear order. However, the existence itself and the nature of this structure is still uncertain. Although the techniques used for the visualization of the nuclear matrix have improved over the years, it is still unclear to what extent the isolated nuclear matrix corresponds to an in vivo existing structure. Therefore, considerable skepticism continues to surround the nuclear matrix fraction as an accurate representation of the situation in living cells. Here, we summarize the experimental evidence in favor of, or against, the presence of a diffuse nucleoskeleton as a facilitating organizational nonchromatin structure of the nucleus.

  6. Regulatory decision with EPA/NRC/DOE/State Session (Panel)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    O`Donnell, E.

    1995-12-31

    This panel will cover the Nuclear Regulatory Commission`s (NRC) proposed radiation limits in the Branch Technical Position on Low-Level Radioactive Waste Performance Assessment and the Environmental Protection Agency`s (EPA) draft regulation in Part 193. Representatives from NRC and EPA will discuss the inconsistencies in these two regulations. DOE and state representatives will discuss their perspective on how these regulations will affect low-level radioactive waste performance assessments.

  7. Fifth international fungus spore conference. [Abstracts]: Final technical report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Timberlake, W.E.

    1993-04-01

    This folio contains the proceedings of the Fifth International Fungal Spore Conference held August 17-21, 1991 at the Unicoi State Park at Helen, Georgia. The volume contains abstracts of each oral presentation as well as a collection of abstracts describing the poster sessions. Presentations were organized around the themes (1) Induction of Sporulation, (2) Nuclear Division, (3) Spore Formation, (4) Spore Release and Dispersal, and (4) Spore Germination.

  8. MO-AB-207-00: ACR Update in MR, CT, Nuclear Medicine, and Mammography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date asmore » the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program.« less

  9. MO-AB-207-03: ACR Update in Nuclear Medicine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Harkness, B.

    A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date asmore » the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program.« less

  10. Gastroenterology training in a resource-limited setting: Zambia, Southern Africa

    PubMed Central

    Asombang, Akwi W; Turner-Moss, Eleanor; Seetharam, Anil; Kelly, Paul

    2013-01-01

    AIM: To evaluate need for and efficacy of a structured gastroenterology didactic session in expanding awareness and understanding of digestive disorders. METHODS: A four-day symposium was developed with didactic sessions (days 1, 2) and practical endoscopy (days 3, 4). Didactic sessions included case presentations highlighting pathophysiology and management. One nurse and four practicing gastroenterologists from the United Kingdom led lectures and supervised workshops with audience participation. Practical endoscopy focused on diagnostic and therapeutic procedures and their application to diagnosis and treatment of ailments of the gastrointestinal tract. Pre- and post-workshop questionnaires were distributed to participants during didactic sessions. A pre-workshop questionnaire gauged expectations and identified objectives to be met at the symposium. Post-workshop questionnaires were administered to assess efficacy of each session. Participants graded sessions from 1 (poor) to 5 (excellent) on quality of case presentations, knowledge, clarity and mode of presentation. We assessed if time allotted to each topic was sufficient, value of sessions, impact on practice and interest in future symposiums. RESULTS: There were 46 attendees on day 1: 41% undergraduates, 41% residents, 11% consultants and 4% unspecified. Day 2 (a Saturday) had 24 participants: 17% undergraduates, 71% residents, 9% consultants, 4% unspecified. Primary pre-workshop symposium expectation was to gain knowledge in: general gastroenterology (55.5%), practical endoscopy (13.8%), pediatric gastroenterology (5%), epidemiology of gastrointestinal disorders specific to Zambia (6%), and interaction with international speakers (6%). The post-symposium questionnaire was answered by 19 participants, of whom 95% felt specific aims were met; all would attend future conferences and recommend to others. CONCLUSION: The beneficial effect of a structured symposium in developing countries warrants further attention as a mechanism to improve disease awareness in areas where resources are limited. PMID:23840144

  11. Gastroenterology training in a resource-limited setting: Zambia, Southern Africa.

    PubMed

    Asombang, Akwi W; Turner-Moss, Eleanor; Seetharam, Anil; Kelly, Paul

    2013-07-07

    To evaluate need for and efficacy of a structured gastroenterology didactic session in expanding awareness and understanding of digestive disorders. A four-day symposium was developed with didactic sessions (days 1, 2) and practical endoscopy (days 3, 4). Didactic sessions included case presentations highlighting pathophysiology and management. One nurse and four practicing gastroenterologists from the United Kingdom led lectures and supervised workshops with audience participation. Practical endoscopy focused on diagnostic and therapeutic procedures and their application to diagnosis and treatment of ailments of the gastrointestinal tract. Pre- and post-workshop questionnaires were distributed to participants during didactic sessions. A pre-workshop questionnaire gauged expectations and identified objectives to be met at the symposium. Post-workshop questionnaires were administered to assess efficacy of each session. Participants graded sessions from 1 (poor) to 5 (excellent) on quality of case presentations, knowledge, clarity and mode of presentation. We assessed if time allotted to each topic was sufficient, value of sessions, impact on practice and interest in future symposiums. There were 46 attendees on day 1: 41% undergraduates, 41% residents, 11% consultants and 4% unspecified. Day 2 (a Saturday) had 24 participants: 17% undergraduates, 71% residents, 9% consultants, 4% unspecified. Primary pre-workshop symposium expectation was to gain knowledge in: general gastroenterology (55.5%), practical endoscopy (13.8%), pediatric gastroenterology (5%), epidemiology of gastrointestinal disorders specific to Zambia (6%), and interaction with international speakers (6%). The post-symposium questionnaire was answered by 19 participants, of whom 95% felt specific aims were met; all would attend future conferences and recommend to others. The beneficial effect of a structured symposium in developing countries warrants further attention as a mechanism to improve disease awareness in areas where resources are limited.

  12. Incorporating a Rich Media Presentation Format into a Lecture-Based Course Structure

    ERIC Educational Resources Information Center

    Moss, Nicholas

    2005-01-01

    The e-syllabus is a set of Web pages in which each course in the curriculum is assigned a "course page" and multiple "session pages." Course pages have a standardized format that provides course objectives, course policies, required or recommended textbooks, grading scales, and faculty listings. A separate session page is…

  13. Frontiers of Crystallography: A Project-Based Research-Led Learning Exercise

    ERIC Educational Resources Information Center

    Wilson, Chick C.; Parkin, Andrew; Thomas, Lynne H.

    2012-01-01

    A highly interactive research-led learning session for chemistry undergraduates is described, which aims to lead students to an awareness of the applications of crystallography technique through a mentored hands-on crystal structure solution and refinement session. The research-based environment is inherent throughout the 4.5 h program and is…

  14. Periodic Review Sessions Contribute to Student Learning across the Disciplines in Pharmacology

    ERIC Educational Resources Information Center

    Barry, Orla P.; O' Sullivan, Eleanor; McCarthy, Marian

    2015-01-01

    Background: The teaching of the discipline of pharmacology is in constant flux. In order to meet the challenges of teaching pharmacology effectively we investigated a new teaching and learning strategy. Aim: Our aim was to investigate whether structured periodic review sessions (RS) could improve teaching and learning for students in a…

  15. Structural Integrity and Durability of Reusable Space Propulsion Systems

    NASA Technical Reports Server (NTRS)

    1989-01-01

    Presentations were made by industry, university, and government researchers organized into four sessions: aerothermodynamic loads; instrumentation; fatigue, fracture, and constitutive modeling; and structural dynamics.

  16. Preface

    NASA Astrophysics Data System (ADS)

    Lexcellent, C.; Patoor, E.

    2004-06-01

    This international conference was held between the 18 and the 23th may 2003, in the "Villa Clythia" belonging to the CAES of the french "Comité National de la Recherche Scientifique CNRS" at Fréjus (France). The scope of this EMMC7 conference was about the use of smart materials which permits the conception of some adaptive systems for industrial applications. A special attention was devoted to active and passive controls of damping in structures. The use of this new class of materials (shape memory alloys, piezoelectric ceramics, TRIP steels, ferromagnetic shape memory alloys, ...) implies the development of numerical tools for computer assisted design process. Complexity of the involved material behaviour requires a deep understanding of strain mechanisms (martensitic phase transformation, reorientation process of domains), the use of accurate experimental techniques and advanced modelling approaches at various scale (micro, meso, macroscopic). In this purpose, it is necessary to use some coupled calculations connecting different fields of physics such as thermal, electromagnetism, electricity and mechanics of materials ones. The conference topic gave the opportunity of fruitful discussions between the mechanics of materials communauty and the specialists of damping or passive control. The scientific program contains nine oral sessions and one poster session. - Experimental characterization of the shape memory alloys thermomechanical behavior (two sessions) - Modeling of the shape memory alloy thermomechanical behavior (two sessions) - Ferromagnetic shape memory alloys behavior (one session) - Piezoelectric ceramics behavior (one session) - Transformation induced plasticity steel behavior (one session) - Hybrid structures including smart materials as sensor or actuator (one session) - Adaptive structure for vibration control (one session) - Poster session. The conference programm contains 50 lectures. 57 scientists were present and come from 14 different countries: 20 from France, 7 from Germany, 6 from Italy, 4 from Russia, 4 from Finland and 5 from USA ... This scientific programm allows all the participants interesting exchanges on "the state of art" about smart materials and adaptive systems. In the aim of its publication in the Proceedings of the EMMC7 Conference (EDP Sciences "Journal de Physique IV") each paper was expertised by two reviewers belonging to the International Scientific Committee and also other specialists. On that occasion, we will thank them for their very important contribution of the scientific level quality of the Proceedings. We will also thank: the sponsors of the Conference: Délégation Générale aux Armements (DGA), le Ministère de la Recherche, l'Université de Metz, l'ENSAM, le CNRS, l'Association Française de Mécanique et l'Institut des Microtechniques de Franche-Comté, the members of the organizing committee, the MECAMAT committee for trusting us, EDP Sciences for the Proceedings, The "Villa Clythia" team for his nice help in the material organization, ... and all the participants. The Co-chairmen Christian LEXCELLENT et Étienne PATOOR

  17. Inter- and intramuscular differences in training-induced hypertrophy of the quadriceps femoris: association with muscle activation during the first training session.

    PubMed

    Wakahara, Taku; Ema, Ryoichi; Miyamoto, Naokazu; Kawakami, Yasuo

    2017-07-01

    The purpose of this study was to examine whether inter- and intramuscular differences in hypertrophy induced by resistance training correspond to differences in muscle activation during the first training session. Eleven young men completed 12 weeks of training intervention for knee extension. Before and after the intervention, T1-weighted magnetic resonance (MR) images were recorded to determine the volume and anatomical cross-sectional area (CSA) along the length of the individual muscles of the quadriceps femoris. The T2-weighted MR images were also acquired before and immediately after the first training session. The T2 was calculated for each pixel within the quadriceps femoris, from which the muscle activation was evaluated as %activated volume and area. The results showed that the %activated volume after the first training session was significantly higher in the vastus intermedius than the vastus medialis. However, the relative change in muscle volume after the training intervention was significantly greater in the rectus femoris than the vasti muscles (vastus lateralis, intermedius and medialis). Within the rectus femoris, both the %activated area and relative increase in CSA were significantly greater in the distal region than the proximal region. In contrast, the %activated area and relative increase in CSA of the vasti were nearly uniform along each muscle. These results suggest that the muscle activation during the first training session is associated with the intramuscular difference in hypertrophy induced by training intervention, but not with the intermuscular difference. © 2015 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  18. THE CELESTIAL REFERENCE FRAME AT 24 AND 43 GHz. II. IMAGING

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Charlot, P.; Boboltz, D. A.; Fey, A. L.

    2010-05-15

    We have measured the submilliarcsecond structure of 274 extragalactic sources at 24 and 43 GHz in order to assess their astrometric suitability for use in a high-frequency celestial reference frame (CRF). Ten sessions of observations with the Very Long Baseline Array have been conducted over the course of {approx}5 years, with a total of 1339 images produced for the 274 sources. There are several quantities that can be used to characterize the impact of intrinsic source structure on astrometric observations including the source flux density, the flux density variability, the source structure index, the source compactness, and the compactness variability.more » A detailed analysis of these imaging quantities shows that (1) our selection of compact sources from 8.4 GHz catalogs yielded sources with flux densities, averaged over the sessions in which each source was observed, of about 1 Jy at both 24 and 43 GHz, (2) on average the source flux densities at 24 GHz varied by 20%-25% relative to their mean values, with variations in the session-to-session flux density scale being less than 10%, (3) sources were found to be more compact with less intrinsic structure at higher frequencies, and (4) variations of the core radio emission relative to the total flux density of the source are less than 8% on average at 24 GHz. We conclude that the reduction in the effects due to source structure gained by observing at higher frequencies will result in an improved CRF and a pool of high-quality fiducial reference points for use in spacecraft navigation over the next decade.« less

  19. Summary of Session Activities: Coordination of Environmental Education Projects

    NASA Technical Reports Server (NTRS)

    Keeler, Michael; Mahootian, Farzad

    1995-01-01

    In this session, we address four fundamental questions related to environmental fields with emphasis on education. These are: What are the goals, objectives, and practical opportunities for coordinating our projects? How can we improve awareness of, interest in, access to, and support the products of our work? How can we build relationships between projects for scientific, educational, technical, and programmatic benefit? How can we evaluate the effectiveness of coordination efforts. In this working session, we produced answers to these questions and proposed a structure for future collaboration.

  20. The nuclear matrix prepared by amine modification

    PubMed Central

    Wan, Katherine M.; Nickerson, Jeffrey A.; Krockmalnic, Gabriela; Penman, Sheldon

    1999-01-01

    The nucleus is spatially ordered by attachments to a nonchromatin nuclear structure, the nuclear matrix. The nuclear matrix and chromatin are intimately connected and integrated structures, and so a major technical challenge in nuclear matrix research has been to remove chromatin while retaining a native nuclear matrix. Most methods for removing chromatin require first a nuclease digestion and then a salt extraction to remove cut chromatin. We have hypothesized that cut chromatin is held in place by charge interactions involving nucleosomal amino groups. We have tested this hypothesis by chemically modifying amino groups after nuclease digestion. By using this protocol, chromatin could be effectively removed at physiological ionic strength. We compared the ultrastructure and composition of this nuclear matrix preparation with the traditional high-salt nuclear matrix and with the third nuclear matrix preparation that we have developed from which chromatin is removed after extensive crosslinking. All three matrix preparations reveal internal nuclear matrix structures that are built on a network of branched filaments of about 10 nm diameter. That such different chromatin-removal protocols reveal similar principles of nuclear matrix construction increases our confidence that we are observing important architectural elements of the native structure in the living cell. PMID:9927671

  1. PREFACE: Second Meeting of the APS Topical Group on Hadronic Physics

    NASA Astrophysics Data System (ADS)

    Ernst, David; de Jager, Kees; Roberts, Craig; Sheldon, Paul; Swanson, Eric

    2007-06-01

    The Second Meeting of the APS Topical Group on Hadronic Physics was held on 22-24 October 2006 at the Opryland Resort in Nashville, Tennessee. Keeping with tradition, the meeting was held in conjunction with the Fall meeting of the APS Division of Nuclear Physics. Approximately 90 physicists participated in the meeting, presenting 25 talks in seven plenary sessions and 48 talks in 11 parallel sessions. These sessions covered a wide range of topics related to strongly interacting matter. Among these were charm spectroscopy, gluonic exotics, nucleon resonance physics, RHIC physics, electroweak and spin physics, lattice QCD initiatives, and new facilities. Brad Tippens and Brad Keister provided perspective from the funding agencies. The organisers are extremely grateful to the following institutions for financial and logistical support: the American Physical Society, Jefferson Lab, Brookhaven National Laboratory, and Vanderbilt University. We thank the following persons for assisting in organising the parallel sessions: Ted Barnes, Jian-Ping Chen, Ed Kinney, Krishna Kumar, Harry Lee, Mike Leitch, Kam Seth, and Dennis Weygand. We also thank Gerald Ragghianti for designing the conference poster, Will Johns for managing the audio-visual equipment and for placing the talks on the web, Sandy Childress for administrative expertise, and Vanderbilt graduate students Eduardo Luiggi and Jesus Escamillad for their assistance. David Ernst, Kees de Jager, Craig Roberts (Chair), Paul Sheldon and Eric Swanson Editors

  2. Stability Analysis of Plates and Shells

    NASA Technical Reports Server (NTRS)

    Knight, Norman F., Jr. (Compiler); Nemeth, Michael P. (Compiler)

    1998-01-01

    This special publication contains the papers presented at the special sessions honoring Dr. Manuel Stein during the 38th AIAA/ASME/ASCE/AHS/ASC Structures, Structural Dynamics, and Materials Conference held in Kissimmee, Florida, Apdl 7-10, 1997. This volume, and the SDM special sessions, are dedicated to the memory of Dr. Manuel Stein, a major pioneer in structural mechanics, plate and shell buckling, and composite structures. Many of the papers presented are the work of Manny's colleagues and co-workers and are a result, directly or indirectly, of his influence. Dr. Stein earned his Ph.D. in Engineering Mechanics from Virginia Polytechnic Institute and State University in 1958. He worked in the Structural Mechanics Branch at the NASA Langley Research Center from 1943 until 1989. Following his retirement, Dr. Stein continued his involvement with NASA as a Distinguished Research Associate.

  3. [Modelling of phosphorus transfers during haemodialysis].

    PubMed

    Chazot, Guillaume; Lemoine, Sandrine; Juillard, Laurent

    2017-04-01

    Chronic kidney disease causes hyperphosphatemia, which is associated with increased cardiovascular risk and mortality. In patients with end-stage renal disease, haemodialysis allows the control of hyperphosphatemia. During a 4-h haemodialysis session, between 600 and 700mg of phosphate are extracted from the plasma, whereas the latter contains only 90mg of inorganic phosphate. The precise origin of phosphates remains unknown. The modelling of phosphorus transfers allows to predict the outcome after changes in dialysis prescription (duration, frequency) with simple two-compartment models and to describe the transfers between the different body compartments with more complex models. Work using 31 P nuclear magnetic resonance spectroscopy performed in animals showed an increase in intracellular phosphate concentration and a decrease in intracellular ATP during a haemodialysis session suggesting an intracellular origin of phosphates. Copyright © 2017. Published by Elsevier Masson SAS.

  4. Women of the Manhattan Project

    NASA Astrophysics Data System (ADS)

    Marshall, Jill

    2009-10-01

    In the book Their Day in the Sun, Ruth Howes and Caroline Herzenberg documented more than 1000 women who worked on the Manhattan Project, preserving their legacy for generations to come. At the 2009 Chicago meeting, the AAPT Committee on Women in Physics celebrated the accomplishments of these women and the men who worked beside them. Howes presented an overview of the contributions of women to the development of the first nuclear weapon, and the session was honored with talks from two Manhattan project veterans, Ellen Cleminshaw Weaver, who worked at Oak Ridge, and Dorothy Marcus Gans, who worked as a technician in the Metallurgical Laboratory in Chicago. I will present a summary of the session, analyzing the effect of working on the project on the career trajectories of the women involved, and point listeners toward additional documentation of this history.

  5. Integrative structure and functional anatomy of a nuclear pore complex

    NASA Astrophysics Data System (ADS)

    Kim, Seung Joong; Fernandez-Martinez, Javier; Nudelman, Ilona; Shi, Yi; Zhang, Wenzhu; Raveh, Barak; Herricks, Thurston; Slaughter, Brian D.; Hogan, Joanna A.; Upla, Paula; Chemmama, Ilan E.; Pellarin, Riccardo; Echeverria, Ignacia; Shivaraju, Manjunatha; Chaudhury, Azraa S.; Wang, Junjie; Williams, Rosemary; Unruh, Jay R.; Greenberg, Charles H.; Jacobs, Erica Y.; Yu, Zhiheng; de La Cruz, M. Jason; Mironska, Roxana; Stokes, David L.; Aitchison, John D.; Jarrold, Martin F.; Gerton, Jennifer L.; Ludtke, Steven J.; Akey, Christopher W.; Chait, Brian T.; Sali, Andrej; Rout, Michael P.

    2018-03-01

    Nuclear pore complexes play central roles as gatekeepers of RNA and protein transport between the cytoplasm and nucleoplasm. However, their large size and dynamic nature have impeded a full structural and functional elucidation. Here we determined the structure of the entire 552-protein nuclear pore complex of the yeast Saccharomyces cerevisiae at sub-nanometre precision by satisfying a wide range of data relating to the molecular arrangement of its constituents. The nuclear pore complex incorporates sturdy diagonal columns and connector cables attached to these columns, imbuing the structure with strength and flexibility. These cables also tie together all other elements of the nuclear pore complex, including membrane-interacting regions, outer rings and RNA-processing platforms. Inwardly directed anchors create a high density of transport factor-docking Phe-Gly repeats in the central channel, organized into distinct functional units. This integrative structure enables us to rationalize the architecture, transport mechanism and evolutionary origins of the nuclear pore complex.

  6. Integrative structure and functional anatomy of a nuclear pore complex.

    PubMed

    Kim, Seung Joong; Fernandez-Martinez, Javier; Nudelman, Ilona; Shi, Yi; Zhang, Wenzhu; Raveh, Barak; Herricks, Thurston; Slaughter, Brian D; Hogan, Joanna A; Upla, Paula; Chemmama, Ilan E; Pellarin, Riccardo; Echeverria, Ignacia; Shivaraju, Manjunatha; Chaudhury, Azraa S; Wang, Junjie; Williams, Rosemary; Unruh, Jay R; Greenberg, Charles H; Jacobs, Erica Y; Yu, Zhiheng; de la Cruz, M Jason; Mironska, Roxana; Stokes, David L; Aitchison, John D; Jarrold, Martin F; Gerton, Jennifer L; Ludtke, Steven J; Akey, Christopher W; Chait, Brian T; Sali, Andrej; Rout, Michael P

    2018-03-22

    Nuclear pore complexes play central roles as gatekeepers of RNA and protein transport between the cytoplasm and nucleoplasm. However, their large size and dynamic nature have impeded a full structural and functional elucidation. Here we determined the structure of the entire 552-protein nuclear pore complex of the yeast Saccharomyces cerevisiae at sub-nanometre precision by satisfying a wide range of data relating to the molecular arrangement of its constituents. The nuclear pore complex incorporates sturdy diagonal columns and connector cables attached to these columns, imbuing the structure with strength and flexibility. These cables also tie together all other elements of the nuclear pore complex, including membrane-interacting regions, outer rings and RNA-processing platforms. Inwardly directed anchors create a high density of transport factor-docking Phe-Gly repeats in the central channel, organized into distinct functional units. This integrative structure enables us to rationalize the architecture, transport mechanism and evolutionary origins of the nuclear pore complex.

  7. Condensins exert force on chromatin-nuclear envelope tethers to mediate nucleoplasmic reticulum formation in Drosophila melanogaster.

    PubMed

    Bozler, Julianna; Nguyen, Huy Q; Rogers, Gregory C; Bosco, Giovanni

    2014-12-30

    Although the nuclear envelope is known primarily for its role as a boundary between the nucleus and cytoplasm in eukaryotes, it plays a vital and dynamic role in many cellular processes. Studies of nuclear structure have revealed tissue-specific changes in nuclear envelope architecture, suggesting that its three-dimensional structure contributes to its functionality. Despite the importance of the nuclear envelope, the factors that regulate and maintain nuclear envelope shape remain largely unexplored. The nuclear envelope makes extensive and dynamic interactions with the underlying chromatin. Given this inexorable link between chromatin and the nuclear envelope, it is possible that local and global chromatin organization reciprocally impact nuclear envelope form and function. In this study, we use Drosophila salivary glands to show that the three-dimensional structure of the nuclear envelope can be altered with condensin II-mediated chromatin condensation. Both naturally occurring and engineered chromatin-envelope interactions are sufficient to allow chromatin compaction forces to drive distortions of the nuclear envelope. Weakening of the nuclear lamina further enhanced envelope remodeling, suggesting that envelope structure is capable of counterbalancing chromatin compaction forces. Our experiments reveal that the nucleoplasmic reticulum is born of the nuclear envelope and remains dynamic in that they can be reabsorbed into the nuclear envelope. We propose a model where inner nuclear envelope-chromatin tethers allow interphase chromosome movements to change nuclear envelope morphology. Therefore, interphase chromatin compaction may be a normal mechanism that reorganizes nuclear architecture, while under pathological conditions, such as laminopathies, compaction forces may contribute to defects in nuclear morphology. Copyright © 2015 Bozler et al.

  8. Condensins Exert Force on Chromatin-Nuclear Envelope Tethers to Mediate Nucleoplasmic Reticulum Formation in Drosophila melanogaster

    PubMed Central

    Bozler, Julianna; Nguyen, Huy Q.; Rogers, Gregory C.; Bosco, Giovanni

    2014-01-01

    Although the nuclear envelope is known primarily for its role as a boundary between the nucleus and cytoplasm in eukaryotes, it plays a vital and dynamic role in many cellular processes. Studies of nuclear structure have revealed tissue-specific changes in nuclear envelope architecture, suggesting that its three-dimensional structure contributes to its functionality. Despite the importance of the nuclear envelope, the factors that regulate and maintain nuclear envelope shape remain largely unexplored. The nuclear envelope makes extensive and dynamic interactions with the underlying chromatin. Given this inexorable link between chromatin and the nuclear envelope, it is possible that local and global chromatin organization reciprocally impact nuclear envelope form and function. In this study, we use Drosophila salivary glands to show that the three-dimensional structure of the nuclear envelope can be altered with condensin II-mediated chromatin condensation. Both naturally occurring and engineered chromatin-envelope interactions are sufficient to allow chromatin compaction forces to drive distortions of the nuclear envelope. Weakening of the nuclear lamina further enhanced envelope remodeling, suggesting that envelope structure is capable of counterbalancing chromatin compaction forces. Our experiments reveal that the nucleoplasmic reticulum is born of the nuclear envelope and remains dynamic in that they can be reabsorbed into the nuclear envelope. We propose a model where inner nuclear envelope-chromatin tethers allow interphase chromosome movements to change nuclear envelope morphology. Therefore, interphase chromatin compaction may be a normal mechanism that reorganizes nuclear architecture, while under pathological conditions, such as laminopathies, compaction forces may contribute to defects in nuclear morphology. PMID:25552604

  9. H.R. 2572: A Bill to amend the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 to establish citizens advisory boards for Department of Energy defense nuclear facilities and to require the Administrator of the Agency for Toxic Substances and Disease Registry to conduct public health and exposure assessments of such facilities. Introduced in the House of Representatives, One Hundred Third Congress, First Session, June 30, 1993

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    The report H.R. 2572 is a bill to amend the Comprehensive Environmental Response, Compensation, and Liabilities Act of 1980 to establish citizen advisory boards for Department of Energy defense nuclear facilities and to require the Administrator of the Agency for Toxic Substances and Disease Registry to conduct public health and exposure assessments of such facilities. The proposed legislative text is included.

  10. Summary of SMIRT20 Preconference Topical Workshop – Identifying Structural Issues in Advanced Reactors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    William Richins; Stephen Novascone; Cheryl O'Brien

    Summary of SMIRT20 Preconference Topical Workshop – Identifying Structural Issues in Advanced Reactors William Richins1, Stephen Novascone1, and Cheryl O’Brien1 1Idaho National Laboratory, US Dept. of Energy, Idaho Falls, Idaho, USA, e-mail: William.Richins@inl.gov The Idaho National Laboratory (INL, USA) and IASMiRT sponsored an international forum Nov 5-6, 2008 in Porvoo, Finland for nuclear industry, academic, and regulatory representatives to identify structural issues in current and future advanced reactor design, especially for extreme conditions and external threats. The purpose of this Topical Workshop was to articulate research, engineering, and regulatory Code development needs. The topics addressed by the Workshop were selectedmore » to address critical industry needs specific to advanced reactor structures that have long lead times and can be the subject of future SMiRT technical sessions. The topics were; 1) structural/materials needs for extreme conditions and external threats in contemporary (Gen. III) and future (Gen. IV and NGNP) advanced reactors and 2) calibrating simulation software and methods that address topic 1 The workshop discussions and research needs identified are presented. The Workshop successfully produced interactive discussion on the two topics resulting in a list of research and technology needs. It is recommended that IASMiRT communicate the results of the discussion to industry and researchers to encourage new ideas and projects. In addition, opportunities exist to retrieve research reports and information that currently exists, and encourage more international cooperation and collaboration. It is recommended that IASMiRT continue with an off-year workshop series on select topics.« less

  11. [MORPHOLOGICAL DIFFERENCES BETWEEN THE EFFECTS OF VARIOUS MODES OF PRECONDITIONING AIMED AT CORRECTING THE DAMAGE TO THE HIPPOCAMPAL NEURONS BY SEVERE HYPOBARIC HYPOXIA].

    PubMed

    Samoilov, M O; Churilova, A V; Glushchenko, T S

    2015-01-01

    In 5 groups of rats (6 animals in each), the changes of neurons in hippocampal fields CA1 and CA4 were studied 7 days after severe hypobaric hypoxia (180 mm Hg, for 3 h) preceded by various numbers (1, 3 and 6) of sessions of preconditioning (PC) by mild hypobaric hypoxia (360 mm Hg, for 2 h, 24 h prior to severe hypoxia). It was found that a single session of PC did not prevent the damage to the structure of neurons and their death after exposure to severe hypoxia. Meanwhile, 6, and especially 3 sessions of PC induced protective mechanisms of neuronal damage prevention. In rats after 6 sessions of PC, unlike those exposed to 3 sessions, mild chromatolysis of hippocampal neurons was demonstrated. This could result from prolonged hypermetabolic activity of neurons and indicate their functional overloading.

  12. 100th anniversary of the birth of I Ya Pomeranchuk (Extended session of the all-institute seminar at the Alikhanov Institute for Theoretical and Experimental Physics, 5 - 6 June 2013)

    NASA Astrophysics Data System (ADS)

    2014-02-01

    On 5 - 6 June 2013, an extended session of the all-institute seminar was held at the Russian Federation State Scientific Center 'Alikhanov Institute for Theoretical and Experimental Physics' (ITEP). It was devoted to the 100th anniversary of the birth of Academician Isaak Yakovlevich Pomeranchuk, the founder of the Theory Department of ITEP. The announced agenda of the session on the ITEP website http://www.itep.ru/rus/Pomeranchuk100.html contained the following reports: (1) Gershtein S S (SRC 'Institute for High Energy Physics', Protvino, Moscow region) "I Ya Pomeranchuk and the large accelerator";(2) Keldysh L V (Lebedev Physical Institute, RAS (FIAN), Moscow) "Dynamic tunneling";(3) Vaks V G (National Research Centre 'Kurchatov Institute' (NRC KI), Moscow) "Brief reminiscences";(4) Smilga A V (Laboratoire Physique Subatomique et des technologies associées, Université de Nantes, France) "Vacuum structure in 3D supersymmetric gauge theories";(5) Khriplovich I B (Budker Institute of Nuclear Physics, SB RAS, Novosibirsk) "Gravitational four-fermion interaction and early Universe dynamics";(6) Dremin I M (FIAN, Moscow) "Elastic scattering of hadrons";(7) Belavin A A (Landau Institute of Theoretical Physics, RAS, Moscow) "Correlators in minimal string models";(8) Voloshin M B (Theoretical Physics Institute, University of Minnesota, USA) "Exotic quarkonium";(9) Nekrasov N A (Institut des hautes études scientifiques (IHES), France) "BPS/CFT correspondence";(10) Zarembo K (Uppsala Universitet, Sweden) "Exact results in supersymmetric theories and AdS/CFT correspondence";(11) Gorsky A S (ITEP, Moscow) "Baryon as a dyon instanton";(12) Blinnikov S I (ITEP, Moscow) "Mirror substance and other models for dark matter";(13) Rubakov V A (Institute for Nuclear Research, RAS, Moscow) "Test-tube Universe";(14) Kancheli O V (ITEP, Moscow) "50 years of reggistics";(15) Shevchenko V I (NRC KI) "In search of the chiral magnetic effect";(16) Kirilin V P (ITEP, Moscow) "Anomalies and long-range action";(17) Narozhny N B (National Research Nuclear University 'MEPhI', Moscow) "Superpower lasers as instruments for studying the properties of vacuum";(18) Kerbikov B O (ITEP, Moscow) "Hadrons in strong magnetic fields";(19) Neznamov V P, Safronov I I (Russian Federal Nuclear Center - All-Russian Scientific Research Institute of Experimental Physics (VNIIEF), Sarov, Nizhny Novgorod region) "A new method for solving the 'Z > 137' problem and determining hydrogen-like energy levels";(20) Vysotsky M I, Godunov S I (ITEP, Moscow) "Critical charge in a superstrong magnetic field";(21) Dolgov A D (Universitè degli Studi di Ferrara, Italy) "Cosmology: from Pomeranchuk to the present day".Papers written around the reports Nos 4, 5, 11, 12, 19 - 21 are published below. The content of report 6 in an extended form is reflected in I M Dremin's 2013 review of the same title published in Phys. Usp. 56 3 (2013). An extended version of report 13 is published in the present issue of Phys. Usp. 57 128 (2014). • Vacuum structure in 3D supersymmetric gauge theories, A V Smilga Physics-Uspekhi, 2014, Volume 57, Number 2, Pages 155-166 • Gravitational four-fermion interaction in the early Universe, A S Rudenko, I B Khriplovich Physics-Uspekhi, 2014, Volume 57, Number 2, Pages 167-170 • Limit cycles in renormalization group dynamics, K M Bulycheva, A S Gorsky Physics-Uspekhi, 2014, Volume 57, Number 2, Pages 171-182 • Mirror matter and other dark matter models, S I Blinnikov Physics-Uspekhi, 2014, Volume 57, Number 2, Pages 183-188 • New method for solving the Z>137 problem and determining hydrogen-like energy levels, V P Neznamov, I I Safronov Physics-Uspekhi, 2014, Volume 57, Number 2, Pages 189-193 • Critical charge in a superstrong magnetic field, M I Vysotskii, S I Godunov Physics-Uspekhi, 2014, Volume 57, Number 2, Pages 194-198 • Cosmology: from Pomeranchuk to the present day, A D Dolgov Physics-Uspekhi, 2014, Volume 57, Number 2, Pages 199-208

  13. Universal Session-Level Change Processes in an Early Session of Psychotherapy: Path Models

    ERIC Educational Resources Information Center

    Kolden, Gregory G.; Chisholm-Stockard, Sarah M.; Strauman, Timothy J.; Tierney, Sandy C.; Mullen, Elizabeth A.; Schneider, Kristin L.

    2006-01-01

    The authors used structural equation modeling to investigate universal change processes identified in the generic model of psychotherapy (GMP). Three path models of increasing complexity were examined in Study 1 in dynamic therapy. The best fitting model from Study one was replicated in Study two for participants receiving either cognitive or…

  14. Teachers' Contribution to the Social Life in Finnish Preschool Classrooms during Structured Learning Sessions

    ERIC Educational Resources Information Center

    Salminen, Jenni; Hännikäinen, Maritta; Poikonen, Pirjo-Liisa; Rasku-Puttonen, Helena

    2014-01-01

    This study aimed to clarify and deepen the knowledge on and understanding of the role that teachers' practices during teacher-led learning sessions play in creating and enhancing social life in Finnish preschool classrooms. Observational data pertaining to 20 preschool teachers were analysed according to the principles of thematic analysis. Four…

  15. Division V: Commission 42: Close Binaries

    NASA Astrophysics Data System (ADS)

    Ribas, Ignasi; Richards, Mercedes T.; Rucinski, Slavek; Bradstreet, David H.; Harmanec, Petr; Kaluzny, Janusz; Mikolajewska, Joanna; Munari, Ulisse; Niarchos, Panagiotis; Olah, Katalin; Pribulla, Theodor; Scarfe, Colin D.; Torres, Guillermo

    2015-08-01

    Commission 42 (C42) co-organized, together with Commission 27 (C27) and Division V (Div V) as a whole, a full day of science and business sessions that were held on 24 August 2012. The program included time slots for discussion of business matters related to Div V, C27 and C42, and two sessions of 2 hours each devoted to science talks of interest to both C42 and C27. In addition, we had a joint session between Div IV and Div V motivated by the proposal to reformulate the division structure of the IAU and the possible merger of the two divisions into a new Div G. The current report gives an account of the matters discussed during the business session of C42.

  16. Worldwide Report, Arms Control

    DTIC Science & Technology

    1985-12-09

    Pershing-2 Siting 12 Attempt to Forestall Accord 13 U.S. Avoids Discussing Numbers 14 PRAVDA on Nuclear Missile Withdrawal From Greece (Moscow PRAVDA...European states. At the last (June) session of the NATO Council, -Denmark and Greece reserved their positions on the point in the final document...MISSILE WITHDRAWAL FROM GREECE PM151515 Moscow PRAVDA in Russian 10 Nov 85 First Edition p 5 [Nikolay Miroshnik "Commentator’s Column": "Start Made

  17. Heat exchange equipment and valve design and operability improvement. NE-Volume 14

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Singh, K.P; Niyogi, K.K.

    1994-12-31

    The papers contained in this volume were presented at the Maurice Holtz Memorial Sessions on Heat Exchanger Equipment and Valve Design and Operability Improvement, as part of the 1994 International Joint Power Generation Conference and Exhibition, October 2--6, in Phoenix, Arizona. These eight papers deal with two types of components--heat exchangers and valves, both of which are used in practically all sensors of the nuclear industry.

  18. JPRS Report, Soviet Union, World Economy and International Affairs, No. 4, April 1988.

    DTIC Science & Technology

    1988-08-03

    platform of the group of UN socialist states which presented at the session a joint memoran- dum on this question. I would not either dramatize or...threats to mankind (an "ecospasm," the unsettled state of international economic relations, including foreign debt, nonequivalent commodity exchange...mechanisms. When we speak of a nuclear-free, nonvio- lent world, it is inconceivable without the controlling influence of the United Nations. [Question

  19. Nuclear matrix and structural and functional compartmentalization of the eucaryotic cell nucleus.

    PubMed

    Razin, S V; Borunova, V V; Iarovaia, O V; Vassetzky, Y S

    2014-07-01

    Becoming popular at the end of the 20th century, the concept of the nuclear matrix implies the existence of a nuclear skeleton that organizes functional elements in the cell nucleus. This review presents a critical analysis of the results obtained in the study of nuclear matrix in the light of current views on the organization of the cell nucleus. Numerous studies of nuclear matrix have failed to provide evidence of the existence of such a structure. Moreover, the existence of a filamentous structure that supports the nuclear compartmentalization appears to be unnecessary, since this function is performed by the folded genome itself.

  20. Evaluated nuclear structure data file

    NASA Astrophysics Data System (ADS)

    Tuli, J. K.

    1996-02-01

    The Evaluated Nuclear Structure Data File (ENSDF) contains the evaluated nuclear properties of all known nuclides, as derived both from nuclear reaction and radioactive decay measurements. All experimental data are evaluated to create the adopted properties for each nuclide. ENSDF, together with other numeric and bibliographic files, can be accessed on-line through the INTERNET or modem, and some of the databases are also available on the World Wide Web. The structure and the scope of ENSDF are presented along with the on-line access system of the National Nuclear Data Center at Brookhaven National Laboratory.

  1. Evaluated nuclear structure data file

    NASA Astrophysics Data System (ADS)

    Tuli, J. K.

    The Evaluated Nuclear Structure Data File (ENSDF) contains the evaluated nuclear properties of all known nuclides. These properties are derived both from nuclear reaction and radioactive decay measurements. All experimental data are evaluated to create the adopted properties for each nuclide. ENSDF, together with other numeric and biographic files, can be accessed on-line through the INTERNET or modem. Some of the databases are also available on the World Wide Web. The structure and the scope of ENSDF are presented along with the on-line access system of the National Nuclear Data Center at Brookhaven National Laboratory.

  2. Generalized Nuclear Data: A New Structure (with Supporting Infrastructure) for Handling Nuclear Data

    NASA Astrophysics Data System (ADS)

    Mattoon, C. M.; Beck, B. R.; Patel, N. R.; Summers, N. C.; Hedstrom, G. W.; Brown, D. A.

    2012-12-01

    The Evaluated Nuclear Data File (ENDF) format was designed in the 1960s to accommodate neutron reaction data to support nuclear engineering applications in power, national security and criticality safety. Over the years, the scope of the format has been extended to handle many other kinds of data including charged particle, decay, atomic, photo-nuclear and thermal neutron scattering. Although ENDF has wide acceptance and support for many data types, its limited support for correlated particle emission, limited numeric precision, and general lack of extensibility mean that the nuclear data community cannot take advantage of many emerging opportunities. More generally, the ENDF format provides an unfriendly environment that makes it difficult for new data evaluators and users to create and access nuclear data. The Cross Section Evaluation Working Group (CSEWG) has begun the design of a new Generalized Nuclear Data (or 'GND') structure, meant to replace older formats with a hierarchy that mirrors the underlying physics, and is aligned with modern coding and database practices. In support of this new structure, Lawrence Livermore National Laboratory (LLNL) has updated its nuclear data/reactions management package Fudge to handle GND structured nuclear data. Fudge provides tools for converting both the latest ENDF format (ENDF-6) and the LLNL Evaluated Nuclear Data Library (ENDL) format to and from GND, as well as for visualizing, modifying and processing (i.e., converting evaluated nuclear data into a form more suitable to transport codes) GND structured nuclear data. GND defines the structure needed for storing nuclear data evaluations and the type of data that needs to be stored. But unlike ENDF and ENDL, GND does not define how the data are to be stored in a file. Currently, Fudge writes the structured GND data to a file using the eXtensible Markup Language (XML), as it is ASCII based and can be viewed with any text editor. XML is a meta-language, meaning that it has a primitive set of definitions for representing hierarchical data/text in a file. Other meta-languages, like HDF5 which stores the data in binary form, can also be used to store GND in a file. In this paper, we will present an overview of the new GND data structures along with associated tools in Fudge.

  3. Flexible session management in a distributed environment

    NASA Astrophysics Data System (ADS)

    Miller, Zach; Bradley, Dan; Tannenbaum, Todd; Sfiligoi, Igor

    2010-04-01

    Many secure communication libraries used by distributed systems, such as SSL, TLS, and Kerberos, fail to make a clear distinction between the authentication, session, and communication layers. In this paper we introduce CEDAR, the secure communication library used by the Condor High Throughput Computing software, and present the advantages to a distributed computing system resulting from CEDAR's separation of these layers. Regardless of the authentication method used, CEDAR establishes a secure session key, which has the flexibility to be used for multiple capabilities. We demonstrate how a layered approach to security sessions can avoid round-trips and latency inherent in network authentication. The creation of a distinct session management layer allows for optimizations to improve scalability by way of delegating sessions to other components in the system. This session delegation creates a chain of trust that reduces the overhead of establishing secure connections and enables centralized enforcement of system-wide security policies. Additionally, secure channels based upon UDP datagrams are often overlooked by existing libraries; we show how CEDAR's structure accommodates this as well. As an example of the utility of this work, we show how the use of delegated security sessions and other techniques inherent in CEDAR's architecture enables US CMS to meet their scalability requirements in deploying Condor over large-scale, wide-area grid systems.

  4. Fission and Properties of Neutron-Rich Nuclei

    NASA Astrophysics Data System (ADS)

    Hamilton, Joseph H.; Ramayya, A. V.; Carter, H. K.

    2008-08-01

    Opening session. Nuclear processes in stellar explosions / M. Wiescher. In-beam [symbol]-ray spectroscopy of neutron-rich nuclei at NSCL / A. Gade -- Nuclear structure I. Shell-model structure of neutron-rich nuclei beyond [symbol]Sn / A. Covello ... [et al.]. Shell structure and evolution of collectivity in nuclei above the [symbol]Sn core / S. Sarkar and M. S. Sarkar. Heavy-ion fusion using density-constrained TDHF / A. S. Umar and V. E. Oberacker. Towards an extended microscopic theory for upper-fp shell nuclei / K. P. Drumev. Properties of the Zr and Pb isotopes near the drip-line / V. N. Tarasov ... [et al.]. Identification of high spin states in [symbol] Cs nuclei and shell model calculations / K. Li ... [et al.]. Recent measurements of spherical and deformed isomers using the Lohengrin fission-fragment spectrometer / G. S. Simpson ... [et al.] -- Nuclear structure II. Nuclear structure investigation with rare isotope spectroscopic investigations at GSI / P. Boutachkov. Exploring the evolution of the shell structures by means of deep inelastic reactions / G. de Anaelis. Probing shell closures in neutron-rich nuclei / R. Krücken for the S277 and REX-ISOLDEMINIBALL collaborations. Structure of Fe isotopes at the limits of the pf-shell / N. Hoteling ... [et al.]. Spectroscopy of K isomers in shell-stabilized trans-fermium nuclei / S. K. Tandel ... [et al.] -- Radioactive ion beam facilities. SPIRAL2 at GANIL: a world leading ISOL facility for the next decade / S. Gales. New physics at the International Facility for Antiproton and Ion Research (FAIR) next to GSI / I. Augustin ... [et al.]. Radioactive beams from a high powered ISOL system / A. C. Shotter. RlKEN RT beam factory / T. Motobayashi. NSCL - ongoing activities and future perspectives / C. K. Gelbke. Rare isotope beams at Argonne / W. F. Henning. HRIBF: scientific highlights and future prospects / J. R. Beene. Radioactive ion beam research done in Dubna / G. M. Ter-Akopian ... [et al.] -- Fission I. Fission-fragment spectroscopy with STEFF / A. G. Smith ... [et al.]. Gamma ray multiplicity of [symbol]Cf spontaneous fission using LiBerACE / D. L. Bleuel ... [et al.]. Excitation energy dependence of fragment mass and total kinetic energy distributions in proton-induced fission of light actinides / I. Nishinaka ... [et al.]. A dynamical calculation of multi-modal nuclear fission / T. Wada and T. Asano. Structure of fission potential energy surfaces in ten-dimensional spaces / V. V. Pashkevich, Y. K Pyatkov and A. V. Unzhakova. A possible enhancement of nuclear fission in scattering with low energy charged particles / V. Gudkov. Dynamical multi-break processes in the [symbol]Sn + [symbol]Ni system at 35 MeV/Nucleon / M. Papa and ISOSPIN-RE VERSE collaboration -- New experimental techniques. MTOF - a high resolution isobar separator for studies of exotic decays / A. Piechaczek ... [et al.]. Development of ORRUBA: a silicon array for the measurement of transfer reactions in inverse kinematics / S. D. Pain ... [et al.]. Indian national gamma array: present & future / R. K. Bhowmik. Absolute intensities of [symbol] rays emitted in the decay of [symbol]U / H. C. Griffin -- Superheavy elements theory and experiments / M. G. Itkis ... [et al.]. Study of superheavy elements at SHIP / S. Hofinann. Heaviest nuclei from [symbol]Ca-induced reactions / Yu. Ts. Oaanessian. Superheavy nuclei and giant nuclear systems / W. Greiner and V. Zagrebaev. Fission approach to alpha-decay of superheavy nuclei / D.N. Poenaru and W. Greiner. Superheavy elements in the Magic Islands / C. Samanta. Relativistic mean field studies of superheavy nuclei / A. V. Afanas jev. Understanding the synthesis of the heaviest nuclei / W. Loveland -- Mass measurements and g-factors. G factor measurements in neutron-rich [symbol]Cf fission fragments, measured using the gammasphere array / R. Orlandi ... [et al.]. Technique for measuring angular correlations and g-factors in neutron rich nuclei produced by the spontaneous fission of [symbol]Cf / A. V. Daniel ... [et al.]. Magnetic moment measurements in a radioactive beam environment / N. Benczer-Koller and G. Kumbartzki. g-Factor measurements of picosecond states: opportunities and limitations of the recoil-in-vacuum method / N. J. Stone ... [et al.]. Precision mass measurements and trap-assisted spectroscopy of fission products from Ni to Pd / A. Jokinen -- Fission II. Fission research at IRMM / F.-J. Hambsch. Fission yield measurements at the IGISOL facility with JYFLTRAP / H. Penttilä ... [et al.]. Fission of radioactive beams and dissipation in nuclear matter / A. Heinz (for the CHARMS collaboration). Fission of [symbol]U at 80 MeVlu and search for new neutron-rich isotopes / C.M. Folden, III ... [et al.]. Measurement of the average energy and multiplicity of prompt-fission neutrons and gamma rays from [symbol], [symbol], and [symbol] for incident neutron energies of 1 to 200 MeV / R. C. Haight ... [et al.]. Fission measurements with DANCE / M. Jandel ... [et al.]. Measured and calculated neutron-induced fission cross sections of [symbol]Pu / F. Tovesson and T. S. Hill. The fission barrier landscape / L. Phair and L. G. Moretto. Fast neutron-induced fission of some actinides and sub-actinides / A. B. Lautev ... [et al.] -- Fission III/Nuclear structure III. Complex structure in even-odd staggering of fission fragment yields / M. Caamāno and F. Rejmund. The surrogate method: past, present and future / S. R. Lesher ... [et al]. Effects of nuclear incompressibility on heavy-ion fusion / H. Esbensen and Ş. Mişicu. High spin states in [symbol]Pm / A. Dhal ... [et al]. Structure of [symbol]Sm, spherical vibrator versus softly deformed rotor / J. B. Gupta -- Astrophysics. Measuring the astrophysical S-factor in plasmas / A. Bonasera ... [et al.]. Is there shell quenching or shape coexistence in Cd isotopes near N = 82? / J. K. Hwang, A. V. Ramayya and J. H. Hamilton. Spectroscopy of neutron-rich palladium and cadmium isostopes near A= 120 / M. A. Stoyer and W. B. Walters -- Nuclear structure IV. First observation of new neutron-rich magnesium, aluminum and silicon isotopes / A. Stolz ... [et al.]. Spectroscopy of [symbol]Na revolution of shell structure with isospin / V. Tripathi ... [et al.]. Rearrangement of proton single particle orbitals in neutron-rich potassium isotopes - spectroscopy of [symbol]K / W. Królas ... [et al.]. Laser spectroscopy and the nature of the shape transition at N [symbol] 60 / B. Cheal ... [et al.]. Study of nuclei near stability as fission fragments following heavy-ion reactions / N. Fotiadis. [symbol]C and [symbol]N: lifetime measurements of their first-excited states / M. Wiedeking ... [et al.] -- Nuclear astrophysics. Isomer spectroscopy near [symbol]Sn - first observation of excited states in [symbol]Cd / M. Pfitzner ... [et al.]. Nuclear masses and what they imply for the structures of neutron rich nuclei / A. Awahamian and A. Teymurazyan. Multiple nucleosynthesis processes in the early universe / F. Montes. Single-neutron structure of neutron-rich nuclei near N = 50 and N = 82 / J. A. Cizewski ... [et al.]. [symbol]Cadmium: ugly duckling or young swan / W. B. Walters ... [et al.] -- Nuclear structure V. Evidence for chiral doublet bands in [symbol]Ru / Y. X. Luo ... [et al.]. Unusual octupole shape deformation terms and K-mixing / J. O. Rasmussen ... [et al.]. Spin assignments, mixing ratios, and g-factors in neutron rich [symbol]Cf fission products / C. Goodin ... [et al.]. Level structures and double [symbol]-bands in [symbol]Mo, [symbol]Mo and [symbol]Ru / S. J. Zhu ... [et al.] -- Nuclear theory. Microscopic dynamics of shape coexistence phenomena around [symbol]Se and [symbol]Kr / N. Hinohara ... [et al.]. Nuclear structure, double beta decay and test of physics beyond the standard model / A. Faessler. Collective modes in elastic nuclear matter / Ş. Mişicu and S. Bastrukov. From N = Z to neutron rich: magnetic moments of Cu isotopes at and above the [symbol]Ni and [symbol]Ni double shell closures - what next? / N. J. Stone, J. R. Stone and U. Köster -- Nuclear structure VI. Decay studies of nuclei near [symbol]Ni / R. Grzywacz. Weakening of the [symbol]Ni core for Z > 28, N > 50? / J. A. Winger ... [et al.]. Coulomb excitation of the odd-A [symbol]Cu isotopes with MINIBALL and REX-ISOLDE / I. Stefanescu ... [et al.]. Neutron single particle states and isomers in odd mass nickel isotopes near [symbol]Ni / M. M. Raiabali ... [et al.]. [symbol] and [symbol]-delayed neutron decay studies of [symbol]Ch at the HRIBF / S. V. Ilvushkin ... [et al.] -- Posters. Properties of Fe, Ni and Zn isotope chains near the drip-line / V. N. Tarasov ... [et al.]. Probing nuclear structure of [symbol]Xe / J. B. Gupta. Shape coexistence in [symbol]Zr and large deformation in [symbol]Zr / J. K. Hwang ... [et al.]. Digital electronics and their application to beta decay spectroscopy / S. N. Liddick, S. Padgett and R. Grzywacz. Nuclear shape and structure in neutron-rich [symbol]Tc / Y. X. Luo ... [et al.]. Speeding up the r-process. Investigation of first forbidden [symbol] decays in N > 50 isotopes near [symbol]Ni / S. Padgett ... [et al.]. Yields of fission products from various actinide targets / E. H. Sveiewski ... [et al.].

  5. Expression of DNAJB12 or DNAJB14 Causes Coordinate Invasion of the Nucleus by Membranes Associated with a Novel Nuclear Pore Structure

    PubMed Central

    Goodwin, Edward C.; Motamedi, Nasim; Lipovsky, Alex; Fernández-Busnadiego, Rubén; DiMaio, Daniel

    2014-01-01

    DNAJB12 and DNAJB14 are transmembrane proteins in the endoplasmic reticulum (ER) that serve as co-chaperones for Hsc70/Hsp70 heat shock proteins. We demonstrate that over-expression of DNAJB12 or DNAJB14 causes the formation of elaborate membranous structures within cell nuclei, which we designate DJANGOS for DNAJ-associated nuclear globular structures. DJANGOS contain DNAJB12, DNAJB14, Hsc70 and markers of the ER lumen and ER and nuclear membranes. Strikingly, they are evenly distributed underneath the nuclear envelope and are of uniform size in any one nucleus. DJANGOS are composed primarily of single-walled membrane tubes and sheets that connect to the nuclear envelope via a unique configuration of membranes, in which the nuclear pore complex appears anchored exclusively to the outer nuclear membrane, allowing both the inner and outer nuclear membranes to flow past the circumference of the nuclear pore complex into the nucleus. DJANGOS break down rapidly during cell division and reform synchronously in the daughter cell nuclei, demonstrating that they are dynamic structures that undergo coordinate formation and dissolution. Genetic studies showed that the chaperone activity of DNAJ/Hsc70 is required for the formation of DJANGOS. Further analysis of these structures will provide insight into nuclear pore formation and function, activities of molecular chaperones, and mechanisms that maintain membrane identity. PMID:24732912

  6. Argonne Physics Division

    Science.gov Websites

    , nuclear structure and reaction research, nuclear theory, medium energy nuclear research and accelerator structure of baryonic matter in the universe - the matter that makes up stars, planets and human life itself

  7. Molecular and Structural Traits of Insulin Receptor Substrate 1/LC3 Nuclear Structures and Their Role in Autophagy Control and Tumor Cell Survival.

    PubMed

    Lassak, Adam; Dean, Mathew; Wyczechowska, Dorota; Wilk, Anna; Marrero, Luis; Trillo-Tinoco, Jimena; Boulares, A Hamid; Sarkaria, Jann N; Del Valle, Luis; Peruzzi, Francesca; Ochoa, Augusto; Reiss, Krzysztof

    2018-05-15

    Insulin receptor substrate 1 (IRS-1) is a common cytosolic adaptor molecule involved in signal transduction from insulin and insulin-like growth factor I (IGF-I) receptors. IRS-1 can also be found in the nucleus. We report here a new finding of unique IRS-1 nuclear structures, which we observed initially in glioblastoma biopsy specimens and glioblastoma xenografts. These nuclear structures can be reproduced in vitro by the ectopic expression of IRS-1 cDNA cloned in frame with the nuclear localization signal (NLS-IRS-1). In these structures, IRS-1 localizes at the periphery, while the center harbors a key autophagy protein, LC3. These new nuclear structures are highly dynamic, rapidly exchange IRS-1 molecules with the surrounding nucleoplasm, disassemble during mitosis, and require a growth stimulus for their reassembly and maintenance. In tumor cells engineered to express NLS-IRS-1, the IRS-1/LC3 nuclear structures repress autophagy induced by either amino acid starvation or rapamycin treatment. In this process, IRS-1 nuclear structures sequester LC3 inside the nucleus, possibly preventing its cytosolic translocation and the formation of new autophagosomes. This novel mechanism provides a quick and reversible way of inhibiting autophagy, which could counteract autophagy-induced cancer cell death under severe stress, including anticancer therapies. Copyright © 2018 American Society for Microbiology.

  8. The Impact of Stress on Odor Perception.

    PubMed

    Hoenen, Matthias; Wolf, Oliver T; Pause, Bettina M

    2017-01-01

    The olfactory system and emotional systems are highly intervened and share common neuronal structures. The current study investigates whether emotional (e.g., anger and fear) and physiological (saliva cortisol) stress responses are associated with odor identification ability and hedonic odor judgments (intensity, pleasantness, and unpleasantness). Nineteen men participated in the modified Trier Social Stress Test (TSST) and a control session (cycling on a stationary bike). The physiological arousal was similar in both sessions. In each session, participants' odor identification score was assessed using the University of Pennsylvania Smell Identification Test, and their transient mood was recorded on the dimensions of valence, arousal, anger, and anxiety. Multivariate regression analyses show that an increase of cortisol in the TSST session (as compared with the control session) is associated with better odor identification performance (β = .491) and higher odor intensity ratings (β = .562). However, increased anger in the TSST session (as compared with the control session) is associated with lower odor identification performance (β = -.482). The study shows divergent effects of the emotional and the physiological stress responses, indicating that an increase of cortisol is associated with better odor identification performance, whereas increased anger is associated with poorer odor identification performance.

  9. Influence of structural integration and fascial fitness on body image and the perception of back pain.

    PubMed

    Baur, Heidi; Gatterer, Hannes; Hotter, Barbara; Kopp, Martin

    2017-06-01

    [Purpose] The aim of this study was to examine the influence of Structural Integration and Fascial Fitness, a new form of physical exercise, on body image and the perception of back pain. [Subjects and Methods] In total, 33 participants with non-specific back pain were split into two groups and performed three sessions of Structural Integration or Fascial Fitness within a 3-week period. Before and after the interventions, perception of back pain and body image were evaluated using standardized questionnaires. [Results] Structural Integration significantly decreased non-specified back pain and improved both "negative body image" and "vital body dynamics". Fascial Fitness led to a significant improvement on the "negative body image" subscale. Benefits of Structural Integration did not significantly vary in magnitude from those for fascial fitness. [Conclusion] Both Structural Integration and Fascial Fitness can lead to a more positive body image after only three sessions. Moreover, the therapeutic technique of Structural Integration can reduce back pain.

  10. Nuclear data and related services

    NASA Astrophysics Data System (ADS)

    Tuli, J. K.

    1985-10-01

    National Nuclear Data Center (NNDC) maintains a number of data bases containing bibliographic information and evaluated as well as experimental nuclear properties. An evaluated computer file maintained by the NNDC, called the Evaluated Nuclear Structure Data File (ENSDF), contains nuclear structure information for all known nuclides. The ENSDF is the source for the journal Nuclear Data Sheets which is produced and edited by NNDC. The Evaluated Nuclear Data File (ENDF), on the other hand is designed for storage and retrieval of such evaluated nuclear data as are used in neutronic, photonic, and decay heat calculations in a large variety of applications. Some of the publications from these data bases are the Nuclear Wallet Cards, Radioactivity Handbook, and books on neutron cross sections and resonance parameters. In addition, the NNDC maintains three bibliographic files: NSR - for nuclear structure and decay data related references, CINDA - a bibliographic file for neutron induced reactions, and CPBIB for charged particle reactions. Selected retrievals from evaluated data and bibliographic files are possible on-line or on request from NNDC.

  11. Packet flow monitoring tool and method

    DOEpatents

    Thiede, David R [Richland, WA

    2009-07-14

    A system and method for converting packet streams into session summaries. Session summaries are a group of packets each having a common source and destination internet protocol (IP) address, and, if present in the packets, common ports. The system first captures packets from a transport layer of a network of computer systems, then decodes the packets captured to determine the destination IP address and the source IP address. The system then identifies packets having common destination IP addresses and source IP addresses, then writes the decoded packets to an allocated memory structure as session summaries in a queue.

  12. Kaon Condensation and the Non-Uniform Nuclear Matter

    NASA Astrophysics Data System (ADS)

    Maruyama, Toshiki; Tatsumi, Toshitaka; Voskresensky, Dmitri N.; Tanigawa, Tomonori; Chiba, Satoshi

    2004-04-01

    Non-uniform structures of nuclear matter are studied in a wide density-range. Using the density functional theory with a relativistic mean-field model, we examine non-uniform structures at sub-nuclear densities (nuclear "pastas") and at high densities, where kaon condensate is expected. We try to give a unified view about the change of the matter structure as density increases, carefully taking into account the Coulomb screening effects from the viewpoint of first-order phase transition.

  13. Effect of Education Sessions of a Structured School Eye Screening Programme on Indian Schoolteachers' Knowledge and Responsibility for Children's Eye Health

    ERIC Educational Resources Information Center

    Thummalapalli, Rohit; Williams, Jachin D.; Khoshnood, Kaveh; Salchow, Daniel J.; Forster, Susan H.

    2013-01-01

    Objective: To evaluate the effect of education sessions on Indian schoolteacher awareness of childhood eye health issues, responsibility for children's eye health, and successful participation in a teacher-led eye screening health intervention programme in primary schools aimed at addressing avoidable childhood blindness in India. Design:…

  14. Peer Assisted Study Sessions and Student Performance: The Role of Academic Engagement, Student Identity, and Statistics Self-Efficacy

    ERIC Educational Resources Information Center

    Spedding, Jason; Hawkes, Amy J.; Burgess, Matthew

    2017-01-01

    The initial year of university is often a sensitive period for new students. Commencing students may lack the necessary skills and resources to adapt to unfamiliar learning environments. One intervention demonstrating academic benefits is Peer Assisted Study Sessions (PASS). PASS is a structured peer led study group where students collectively…

  15. The Effect of Two Types of Corrective Feedback on EFL Learners' Writing Skill

    ERIC Educational Resources Information Center

    Farshi, Sina Soltanabadi; Safa, Saeedeh Khalili

    2015-01-01

    The purpose of this study was to compare the effects of two types of corrective feedback on EFL learners' writing skill. Thirty five advanced learners in three groups participated in this study. Structures of written texts were taught in all three classes during fourteen sessions of treatment; and each session, a related topic was given and the…

  16. Assessment of Titanium Aluminide Alloys for High-Temperature Nuclear Structural Applications

    NASA Astrophysics Data System (ADS)

    Zhu, Hanliang; Wei, Tao; Carr, David; Harrison, Robert; Edwards, Lyndon; Hoffelner, Wolfgang; Seo, Dongyi; Maruyama, Kouichi

    2012-12-01

    Titanium aluminide (TiAl) alloys exhibit high specific strength, low density, good oxidation, corrosion, and creep resistance at elevated temperatures, making them good candidate materials for aerospace and automotive applications. TiAl alloys also show excellent radiation resistance and low neutron activation, and they can be developed to have various microstructures, allowing different combinations of properties for various extreme environments. Hence, TiAl alloys may be used in advanced nuclear systems as high-temperature structural materials. Moreover, TiAl alloys are good materials to be used for fundamental studies on microstructural effects on irradiation behavior of advanced nuclear structural materials. This article reviews the microstructure, creep, radiation, and oxidation properties of TiAl alloys in comparison with other nuclear structural materials to assess the potential of TiAl alloys as candidate structural materials for future nuclear applications.

  17. On the existence of Rydberg nuclear molecules

    NASA Astrophysics Data System (ADS)

    Bertulani, C. A.; Frederico, T.; Hussein, M. S.

    2017-11-01

    Present nuclear detection techniques prevents us from determining if the analogue of a Rydberg molecule exists for the nuclear case. But nothing in nature disallows their existence. As in the atomic case, Rydberg nuclear molecules would be a laboratory for new aspects and applications of nuclear physics. We propose that Rydberg nuclear molecules, which represent the exotic, halo nuclei version, such as 11Be +11Be, of the well known quasimolecules observed in stable nuclei such as 12C +12C, might be common structures that could manifest their existence along the dripline. A study of possible candidates and the expected structure of such exotic clustering of two halo nuclei: the Rydberg nuclear molecules, is made on the basis of three different methods. It is shown that such cluster structures might be stable and unexpectedly common.

  18. Similar hypotensive effects of combined aerobic and resistance exercise with 1 set versus 3 sets in women with metabolic syndrome.

    PubMed

    Tibana, Ramires A; Nascimento, Dahan da C; de Sousa, Nuno M F; de Almeida, Jeeser A; Moraes, Milton R; Durigan, João Luiz Quagliotti; Collier, Scott R; Prestes, Jonato

    2015-11-01

    The aim of the present study was to compare the response of systolic blood pressure (SBP), mean blood pressure (MBP) and diastolic blood pressure (DBP) following combined training with 1 set or with 3 sets of resistance exercise (RE). Sixteen women with metabolic syndrome (MetS) were randomly assigned to perform two combined exercise protocols and a control session (CON): 1-set, 30 min of aerobic exercise (AE) at 65-70% of reserve heart rate and 1 set of 8-12 repetitions at 80% of 10-RM in six resistance exercises; 3-sets, same protocol but with 3 sets; and CON, 30 min of seated rest. The SBP, MBP and DBP were measured before and every 15 min during 90 min following the experimental sessions. The SBP displayed a decrease (P ≤ 0.05) during the 90 min following the RE session with 1-set and 3-set, while MBP was decreased (P ≤ 0.05) up to 75 min after 1-set and up to 30 min after the 3-set exercise session compared with pre-intervention values. There was a decrease in DBP only for the greatest individual decrease following 1-set (-6.1 mmHg) and 3-set (-4.9 mmHg) combined exercise sessions, without differences between them. The rate-pressure product and heart rate remained significantly higher (P ≤ 0.05) 75 min and 90 min after the combined exercise session with 1- and 3-sets compared with the CON, respectively. In conclusion, a low-volume RE combined with AE resulted in similar decrease of SBP when compared with RE with 3-sets in women with MetS, which could be beneficial in situations of limited time. © 2014 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  19. Nuclear Cartography: Patterns in Binding Energies and Subatomic Structure

    ERIC Educational Resources Information Center

    Simpson, E. C.; Shelley, M.

    2017-01-01

    Nuclear masses and binding energies are some of the first nuclear properties met in high school physics, and can be used to introduce radioactive decays, fusion, and fission. With relatively little extension, they can also illustrate fundamental concepts in nuclear physics, such as shell structure and pairing, and to discuss how the elements…

  20. Climatic, biological, and strategic effects of nuclear war. Hearing before the Subcommittee on Natural Resources, Agriculture Research and Environment of the Committee on Science and Technology, House of Representatives, Ninety-Eighth Congress, Second Session, September 12, 1984

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1985-01-01

    A panel of experts, including Carl Sagan, Jay Gould, and Edward Teller, testified along with climate and atmospheric science experts from the Soviet Union on the long-term effects of a nuclear war. The scientists warned that such an event could repeat the biological and climatic disruption that ended the age of dinosaurs 65 million years ago. The purpose of the hearing was to inform committee members about the nature and outcome of a nuclear winter. The scientists also described international research programs designed to ascertain these long-term effects. They pointed out that, while the effects of a single explosion aremore » well known, little is known of overlapping effects from multiple explosions. Two appendices with additional material submitted for the record and additional questions and answers follows the testimony.« less

  1. Casualisation of the teaching workforce: implications for nursing education.

    PubMed

    Halcomb, Elizabeth J; Andrew, Sharon; Peters, Kath; Salamonson, Yenna; Jackson, Debra

    2010-08-01

    Internationally, nursing faculty shortages have been reported and there is a potential for them to worsen into the next decade as existing faculty age. To, in part, address this issue, across disciplines there is clearly an international trend towards the increasing casualisation of the higher education workforce. Despite the potential impact of this two-tiered workforce structure, there has been limited examination of the discipline specific issues related to the employment of a growing number of sessional nursing staff. This paper provides a critical review of the literature related to the employment of sessional teachers in higher education. The paper advances the discourse around the role and implications of employing sessional teachers in undergraduate nursing schools. Recommendations for supporting sessional staff and further research are presented. Copyright 2009 Elsevier Ltd. All rights reserved.

  2. Characterization of a 65 kDa NIF in the nuclear matrix of the monocot Allium cepa that interacts with nuclear spectrin-like proteins.

    PubMed

    Pérez-Munive, Clara; Blumenthal, Sonal S D; de la Espina, Susana Moreno Díaz

    2012-01-01

    Plant cells have a well organized nucleus and nuclear matrix, but lack orthologues of the main structural components of the metazoan nuclear matrix. Although data is limited, most plant nuclear structural proteins are coiled-coil proteins, such as the NIFs (nuclear intermediate filaments) in Pisum sativum that cross-react with anti-intermediate filament and anti-lamin antibodies, form filaments 6-12 nm in diameter in vitro, and may play the role of lamins. We have investigated the conservation and features of NIFs in a monocot species, Allium cepa, and compared them with onion lamin-like proteins. Polyclonal antisera against the pea 65 kDa NIF were used in 1D and 2D Western blots, ICM (imunofluorescence confocal microscopy) and IEM (immunoelectron microscopy). Their presence in the nuclear matrix was analysed by differential extraction of nuclei, and their association with structural spectrin-like proteins by co-immunoprecipitation and co-localization in ICM. NIF is a conserved structural component of the nucleus and its matrix in monocots with Mr and pI values similar to those of pea 65 kDa NIF, which localized to the nuclear envelope, perichromatin domains and foci, and to the nuclear matrix, interacting directly with structural nuclear spectrin-like proteins. Its similarities with some of the proteins described as onion lamin-like proteins suggest that they are highly related or perhaps the same proteins.

  3. The Coming Nuclear Renaissance for Next Generation Safeguards Specialists--Maximizing Potential and Minimizing the Risks

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Eipeldauer, Mary D

    2009-01-01

    This document is intended to provide an overview of the workshop entitled 'The Coming Nuclear Renaissance for the Next Generation Safeguards Experts-Maximizing Benefits While Minimizing Proliferation Risks', conducted at Oak Ridge National Laboratory (ORNL) in partnership with the Y-12 National Security Complex (Y-12) and the Savannah River National Laboratory (SRNL). This document presents workshop objectives; lists the numerous participant universities and individuals, the nuclear nonproliferation lecture topics covered, and the facilities tours taken as part of the workshop; and discusses the university partnership sessions and proposed areas for collaboration between the universities and ORNL for 2009. Appendix A contains themore » agenda for the workshop; Appendix B lists the workshop attendees and presenters with contact information; Appendix C contains graphics of the evaluation form results and survey areas; and Appendix D summarizes the responses to the workshop evaluation form. The workshop was an opportunity for ORNL, Y-12, and SRNL staff with more than 30 years combined experience in nuclear nonproliferation to provide a comprehensive overview of their expertise for the university professors and their students. The overall goal of the workshop was to emphasize nonproliferation aspects of the nuclear fuel cycle and to identify specific areas where the universities and experts from operations and national laboratories could collaborate.« less

  4. Nuclear Pore-Like Structures in a Compartmentalized Bacterium

    PubMed Central

    Sagulenko, Evgeny; Green, Kathryn; Yee, Benjamin; Morgan, Garry; Leis, Andrew; Lee, Kuo-Chang; Butler, Margaret K.; Chia, Nicholas; Pham, Uyen Thi Phuong; Lindgreen, Stinus; Catchpole, Ryan; Poole, Anthony M.; Fuerst, John A.

    2017-01-01

    Planctomycetes are distinguished from other Bacteria by compartmentalization of cells via internal membranes, interpretation of which has been subject to recent debate regarding potential relations to Gram-negative cell structure. In our interpretation of the available data, the planctomycete Gemmata obscuriglobus contains a nuclear body compartment, and thus possesses a type of cell organization with parallels to the eukaryote nucleus. Here we show that pore-like structures occur in internal membranes of G.obscuriglobus and that they have elements structurally similar to eukaryote nuclear pores, including a basket, ring-spoke structure, and eight-fold rotational symmetry. Bioinformatic analysis of proteomic data reveals that some of the G. obscuriglobus proteins associated with pore-containing membranes possess structural domains found in eukaryote nuclear pore complexes. Moreover, immunogold labelling demonstrates localization of one such protein, containing a β-propeller domain, specifically to the G. obscuriglobus pore-like structures. Finding bacterial pores within internal cell membranes and with structural similarities to eukaryote nuclear pore complexes raises the dual possibilities of either hitherto undetected homology or stunning evolutionary convergence. PMID:28146565

  5. Strategic disruption of nuclear pores structure, integrity and barrier for nuclear apoptosis.

    PubMed

    Shahin, Victor

    2017-08-01

    Apoptosis is a programmed cell death playing key roles in physiology and pathophysiology of multi cellular organisms. Its nuclear manifestation requires transmission of the death signals across the nuclear pore complexes (NPCs). In strategic sequential steps apoptotic factors disrupt NPCs structure, integrity and barrier ultimately leading to nuclear breakdown. The present review reflects on these steps. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Promyelocytic Leukemia (Pml) Nuclear Bodies Are Protein Structures That Do Not Accumulate RNA

    PubMed Central

    Boisvert, François-Michel; Hendzel, Michael J.; Bazett-Jones, David P.

    2000-01-01

    The promyelocytic leukemia (PML) nuclear body (also referred to as ND10, POD, and Kr body) is involved in oncogenesis and viral infection. This subnuclear domain has been reported to be rich in RNA and a site of nascent RNA synthesis, implicating its direct involvement in the regulation of gene expression. We used an analytical transmission electron microscopic method to determine the structure and composition of PML nuclear bodies and the surrounding nucleoplasm. Electron spectroscopic imaging (ESI) demonstrates that the core of the PML nuclear body is a dense, protein-based structure, 250 nm in diameter, which does not contain detectable nucleic acid. Although PML nuclear bodies contain neither chromatin nor nascent RNA, newly synthesized RNA is associated with the periphery of the PML nuclear body, and is found within the chromatin-depleted region of the nucleoplasm immediately surrounding the core of the PML nuclear body. We further show that the RNA does not accumulate in the protein core of the structure. Our results dismiss the hypothesis that the PML nuclear body is a site of transcription, but support the model in which the PML nuclear body may contribute to the formation of a favorable nuclear environment for the expression of specific genes. PMID:10648561

  7. WE-F-209-02: Radiation Safety Surveys of Linear Accelerators

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Martin, M.

    2016-06-15

    Over the past few years, numerous Accreditation Bodies, Regulatory Agencies, and State Regulations have implemented requirements for Radiation Safety Surveys following installation or modification to x-ray rooms. The objective of this session is to review best practices in performing radiation safety surveys for both Therapy and Diagnostic installations, as well as a review of appropriate survey instruments. This session will be appropriate for both therapy and imaging physicists who are looking to increase their working knowledge of radiation safety surveys. Learning Objectives: Identify Appropriate Survey Meters for Radiation Safety Surveys Develop best practices for Radiation Safety Surveys for Therapy unitsmore » that include common areas of concern. Develop best practices for Radiation Safety Surveys of Diagnostic and Nuclear Medicine rooms. Identify acceptable dose levels and the factors that affect the calculations associated with performing Radiation Safety Surveys.« less

  8. Nuclear ``pasta'' structures in low-density nuclear matter and properties of the neutron-star crust

    NASA Astrophysics Data System (ADS)

    Okamoto, Minoru; Maruyama, Toshiki; Yabana, Kazuhiro; Tatsumi, Toshitaka

    2013-08-01

    In the neutron-star crust, nonuniform structure of nuclear matter—called the “pasta” structure—is expected. From recent studies of giant flares in magnetars, these structures might be related to some observables and physical quantities of the neutron-star crust. To investigate the above quantities, we numerically explore the pasta structure with a fully three-dimensional geometry and study the properties of low-density nuclear matter, based on the relativistic mean-field model and the Thomas-Fermi approximation. We observe typical pasta structures for fixed proton number fraction and two of them for cold catalyzed matter. We also discuss the crystalline configuration of “pasta.”

  9. Development and validation of a 6-item working alliance questionnaire for repeated administrations during psychotherapy.

    PubMed

    Falkenström, Fredrik; Hatcher, Robert L; Skjulsvik, Tommy; Larsson, Mattias Holmqvist; Holmqvist, Rolf

    2015-03-01

    Recently, researchers have started to measure the working alliance repeatedly across sessions of psychotherapy, relating the working alliance to symptom change session by session. Responding to questionnaires after each session can become tedious, leading to careless responses and/or increasing levels of missing data. Therefore, assessment with the briefest possible instrument is desirable. Because previous research on the Working Alliance Inventory has found the separation of the Goal and Task factors problematic, the present study examined the psychometric properties of a 2-factor, 6-item working alliance measure, adapted from the Working Alliance Inventory, in 3 patient samples (ns = 1,095, 235, and 234). Results showed that a bifactor model fit the data well across the 3 samples, and the factor structure was stable across 10 sessions of primary care counseling/psychotherapy. Although the bifactor model with 1 general and 2 specific factors outperformed the 1-factor model in terms of model fit, dimensionality analyses based on the bifactor model results indicated that in practice the instrument is best treated as unidimensional. Results support the use of composite scores of all 6 items. The instrument was validated by replicating previous findings of session-by-session prediction of symptom reduction using the Autoregressive Latent Trajectory model. The 6-item working alliance scale, called the Session Alliance Inventory, is a promising alternative for researchers in search for a brief alliance measure to administer after every session. 2015 APA, all rights reserved

  10. FUEL ELEMENT FOR A NUCLEAR REACTOR

    DOEpatents

    Davidson, J.K.

    1963-11-19

    A fuel element structure particularly useful in high temperature nuclear reactors is presented. Basically, the structure comprises two coaxial graphite sleeves integrally joined together by radial fins. Due to the high structural strength of graphite at high temperatures and the rigidity of this structure, nuclear fuel encased within the inner sleeve in contiguous relation therewith is supported and prevented from expanding radially at high temperatures. Thus, the necessity of relying on the usual cladding materials with relatively low temperature limitations for structural strength is removed. (AEC)

  11. Applications of a global nuclear-structure model to studies of the heaviest elements

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Moeller, P.; Nix, J.R.

    1993-10-01

    We present some new results on heavy-element nuclear-structure properties calculated on the basis of the finite-range droplet model and folded-Yukawa single-particle potential. Specifically, we discuss calculations of nuclear ground-state masses and microscopic corrections, {alpha}-decay properties, {beta}-decay properties, fission potential-energy surfaces, and spontaneous-fission half-lives. These results, obtained in a global nuclear-structure approach, are particularly reliable for describing the stability properties of the heaviest elements.

  12. Evaluating an undergraduate interprofessional education session for medical and pharmacy undergraduates on therapeutics and prescribing: the medical student perspective

    PubMed Central

    Shelvey, Bethany M; Coulman, Sion A; John, Dai N

    2016-01-01

    Background The current literature on undergraduate interprofessional education (IPE) for pharmacy and medical students highlights a range of positive outcomes, although to date IPE has focused predominantly on student views and experiences of IPE sessions with these opinions being sought at the end of the sessions. This study aimed to evaluate medical students’ experiences of therapeutics and prescribing IPE, with pharmacy students, 1 year following the session. Methods Following ethics committee approval, 3rd year medical students at Cardiff University were invited to participate using non-probability sampling. Topic guide development was informed by the literature and research team discussions, including a review of the materials used in the IPE session. Semi-structured one-to-one interviews explored experiences, prior to, during, and after the IPE session. Interviews were audio-recorded, transcribed verbatim, and analyzed thematically. Results Eighteen medical students were interviewed; 11 were females. Seven themes were identified, namely 1) refinement of pre-session preparation, 2) session value, 3) learning with a pharmacy student, 4) learning about a pharmacist, 5) learning from a pharmacy student, 6) importance and application of what was learnt into practice, and 7) suggestions for change. Conclusion This study provides a valuable insight into medical students’ experiences of a therapeutics and prescribing IPE session and emphasizes the value they placed on interaction with pharmacy students. Medical students were able to recall clear learning experiences from the IPE session that had taken place 12 months earlier, which itself is an indicator of the impact of the session on the students. Furthermore, they were able to describe how knowledge and skills learnt had been applied to subsequent learning activities. Those developing IPE sessions should consider the following: clarify professional roles in the session content, incorporate IPE as a series of activities, and use small groups of students to optimize student–student interaction and active learning. PMID:27980450

  13. How to customize a bona fide psychotherapy for generalized anxiety disorder? A two-arms, patient blinded, ABAB crossed-therapist randomized clinical implementation trial design [IMPLEMENT 2.0].

    PubMed

    Flückiger, Christoph; Wolfer, Christine; Held, Judith; Hilpert, Peter; Rubel, Julian; Allemand, Mathias; Zinbarg, Richard E; Vîslă, Andreea

    2018-04-03

    Bona fide psychotherapy approaches are effective treatments for generalized anxiety disorder (GAD) compared to no-treatment conditions. Treatment manuals and protocols allow a relatively high degree of freedom for the way therapists implement these overall treatment packages and there is a systematic lack of knowledge on how therapists should customize these treatments. The present study experimentally examines two implementation strategies of customizing a bona fide psychotherapy approach based on a 16 session time-limited cognitive-behavioral therapy (CBT) protocol and their relation to the post-session and ultimate treatment outcomes. This trial contrasts two different implementation strategies of how to customize the in-session structure of a manual-based CBT-protocol for GAD. The patients will be randomly assigned to two implementation conditions: (1) a systematic focus on subtle changes lasting from 7 to 20 min at the check-in phase of every psychotherapy session and (2) a state-of-the-art (SOTA) check-in phase lasting several minutes mainly focused on the session goals. Potential therapist effects will be examined based on an ABAB crossed-therapist design. Treatment outcomes will be assessed at the following times: post-session outcomes, treatment outcome at post assessment and 6- as well as 12-month follow-up. The proposed randomized clinical implementation trial addresses the clinically relevant question of how to customize a bona fide psychotherapy protocol experimentally contrasting two implementation strategies. Through the development and testing of the proposed implementation design, this trial has the potential to inform therapists about efficacious implementation strategies of how to customize a manual-based treatment protocol in respect to the timing of the in-session structure. This trial was registered at ClinicalTrials.gov ( NCT03079336 ) at March 14, 2017.

  14. Sanibel Symposium in the Petascale-Exascale Computational Era

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cheng, Hai-Ping

    The 56 th Sanibel Symposium was held February 14-19 2016 at the King and Prince Hotel, St. Simons Island, GA. It successfully brought quantum chemists and chemical and condensed matter physicists together in presentations, posters, and informal discussions bridging those two communities. The Symposium has had a significant role in preparing generations of quantum theorists. As computational potency and algorithmic sophistication have grown, the Symposium has evolved to emphasize more heavily computationally oriented method development in chemistry and materials physics, including nanoscience, complex molecular phenomena, and even bio-molecular methods and problems. Given this context, the 56 th Sanibel meeting systematicallymore » and deliberately had sessions focused on exascale computation. A selection of outstanding theoretical problems that need serious attention was included. Five invited sessions, two contributed sessions (hot topics), and a poster session were organized with the exascale theme. This was a historic milestone in the evolution of the Symposia. Just as years ago linear algebra, perturbation theory, density matrices, and band-structure methods dominated early Sanibel Symposia, the exascale sessions of the 56 thmeeting contributed a transformative influence to add structure and strength to the computational physical science community in an unprecedented way. A copy of the full program of the 56 th Symposium is attached. The exascale sessions were Linear Scaling, Non-Adabatic Dynamics, Interpretive Theory and Models, Computation, Software, and Algorithms, and Quantum Monte Carlo. The Symposium Proceedings will be published in Molecular Physics (2017). Note that the Sanibel proceedings from 2015 and 2014 were published as Molecular Physics vol. 114, issue 3-4 (2016) and vol. 113, issue 3-4 (2015) respectively.« less

  15. Impact of a structured review session on medical student psychiatry subject examination performance.

    PubMed

    Siddiqi, Shan H; Black, Kevin J; Womer, Fay Y

    2015-01-01

    Introduction: The National Board of Medical Examiners (NBME) subject examinations are used as a standardized metric for performance in required clerkships for third-year medical students. While several medical schools have implemented a review session to help consolidate knowledge acquired during the clerkship, the effects of such an intervention are not yet well-established. An improvement in NBME psychiatry examination scores has previously been reported with a single end-of-clerkship review session, but this was limited by a small sample size and the fact that attendance at the review session was optional, leading to likely selection bias. Methods: A 1.5-hour structured review session was conducted for medical students in the last week of each 4-week psychiatry clerkship between September 2014 and July 2015. Students were required to attend unless excused due to scheduling conflicts. Scores on the NBME psychiatry subject exam were compared with those of students taking the examination in the corresponding time period in each of the previous two academic years. Results: 83 students took the exam during the experimental period, while 176 took the exam during the control period. Statistically significant improvements were found in mean score (p=0.03), mean for the two lowest scores in each group (p<0.0007), and percentage of students scoring 70 or less (p=0.03). Percentage of students achieving the maximum possible score (99) was higher in the experimental group, but did not reach significance (p=0.06). Conclusions: An end-of-clerkship review session led to increased mean scores on the NBME psychiatry subject examination, particularly for students at the lower end of the score range. Future research should investigate the impact of such an intervention in other specialties and other institutions.

  16. An Open Trial of a Smartphone-Assisted, Adjunctive Intervention to Improve Treatment Adherence in Bipolar Disorder

    PubMed Central

    Wenze, Susan J.; Armey, Michael F.; Weinstock, Lauren M.; Gaudiano, Brandon A.; Miller, Ivan W.

    2016-01-01

    We evaluated the feasibility and acceptability of a novel, 12 week, adjunctive, smartphone-assisted intervention to improve treatment adherence in bipolar disorder (BD). Eight participants completed 4 in-person individual therapy sessions over the course of a month, followed by 60 days of twice-daily ecological momentary intervention (EMI) sessions, with a fifth in-person session after 30 days and a sixth in-person session after 60 days. Perceived credibility of the intervention and expectancy for change were adequate at baseline, and satisfaction on completion of the intervention was very high. Participants demonstrated good adherence to the intervention overall, including excellent adherence to the in-person component and fair adherence to the smartphone-facilitated component. Qualitative feedback revealed very high satisfaction with the in-person sessions and suggested a broad range of ways in which the EMI sessions were helpful. Participants also provided suggestions for improving the intervention, which primarily related to the structure and administration of the EMI (smartphone-administered) sessions. Although this study was not designed to evaluate treatment efficacy, most key outcome variables changed in the expected directions from pre- to post-treatment, and several variables changed significantly over the course of the in-person sessions or during the EMI phase. These findings add to the small but growing body of literature suggesting that EMIs are feasible and acceptable for use in populations with BD. PMID:27824786

  17. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gottlieb, P.; Robinson, J.H.; Smith, D.R.

    The Nuclear Energy Center siting opportunities in the eleven western states have been systematically examined. The study area has been divided into 10-mile by 10-mile grid cells, and each cell has been evaluated in terms of overall suitability and site-related costs. Composite suitability consists of a weighted sum of ten important nuclear power plant siting issues; the particular weights used for this study were decided by a Delphi session of twenty individuals with energy facility siting expertise, with at least one representative from each of the eleven western states. Site-related costs consist of the additional expenditures required for seismic hardeningmore » (in seismically active areas), electric power transmission lines (for sites significantly far from load centers), and wet/dry cooling system costs (limited water availability and/or high summer temperatures).« less

  18. Proceedings of the Numerical Modeling for Underground Nuclear Test Monitoring Symposium

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Taylor, S.R.; Kamm, J.R.

    1993-11-01

    The purpose of the meeting was to discuss the state-of-the-art in numerical simulations of nuclear explosion phenomenology with applications to test ban monitoring. We focused on the uniqueness of model fits to data, the measurement and characterization of material response models, advanced modeling techniques, and applications of modeling to monitoring problems. The second goal of the symposium was to establish a dialogue between seismologists and explosion-source code calculators. The meeting was divided into five main sessions: explosion source phenomenology, material response modeling, numerical simulations, the seismic source, and phenomenology from near source to far field. We feel the symposium reachedmore » many of its goals. Individual papers submitted at the conference are indexed separately on the data base.« less

  19. Two-level convolution formula for nuclear structure function

    NASA Astrophysics Data System (ADS)

    Ma, Boqiang

    1990-05-01

    A two-level convolution formula for the nuclear structure function is derived in considering the nucleus as a composite system of baryon-mesons which are also composite systems of quark-gluons again. The results show that the European Muon Colaboration effect can not be explained by the nuclear effects as nucleon Fermi motion and nuclear binding contributions.

  20. Maria Goeppert Mayer, the Nuclear Shell Structure, and Magic Numbers

    Science.gov Websites

    dropdown arrow Site Map A-Z Index Menu Synopsis Maria Goeppert-Mayer, the Nuclear Shell Model, and Magic explanation of how neutrons and protons within atomic nuclei are structured. Called the "nuclear shell American husband, chemical physicist Joseph Mayer. At Argonne, Goeppert-Mayer learned most of her nuclear

  1. A New Look to Nuclear Data

    DOE PAGES

    McCutchan, E. A.; Brown, D. A.; Sonzogni, A. A.

    2017-03-30

    Databases of evaluated nuclear data form a cornerstone on which we build academic nuclear structure physics, reaction physics, astrophysics, and many applied nuclear technologies. In basic research, nuclear data are essential for selecting, designing and conducting experiments, and for the development and testing of theoretical models to understand the fundamental properties of atomic nuclei. Likewise, the applied fields of nuclear power, homeland security, stockpile stewardship and nuclear medicine, all have deep roots requiring evaluated nuclear data. Each of these fields requires rapid and easy access to up-to-date, comprehensive and reliable databases. The DOE-funded US Nuclear Data Program is a specificmore » and coordinated effort tasked to compile, evaluate and disseminate nuclear structure and reaction data such that it can be used by the world-wide nuclear physics community.« less

  2. A New Look to Nuclear Data

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McCutchan, E. A.; Brown, D. A.; Sonzogni, A. A.

    Databases of evaluated nuclear data form a cornerstone on which we build academic nuclear structure physics, reaction physics, astrophysics, and many applied nuclear technologies. In basic research, nuclear data are essential for selecting, designing and conducting experiments, and for the development and testing of theoretical models to understand the fundamental properties of atomic nuclei. Likewise, the applied fields of nuclear power, homeland security, stockpile stewardship and nuclear medicine, all have deep roots requiring evaluated nuclear data. Each of these fields requires rapid and easy access to up-to-date, comprehensive and reliable databases. The DOE-funded US Nuclear Data Program is a specificmore » and coordinated effort tasked to compile, evaluate and disseminate nuclear structure and reaction data such that it can be used by the world-wide nuclear physics community.« less

  3. Hands-On Approach to Structure Activity Relationships: The Synthesis, Testing, and Hansch Analysis of a Series of Acetylcholineesterase Inhibitors

    ERIC Educational Resources Information Center

    Locock, Katherine; Tran, Hue; Codd, Rachel; Allan, Robin

    2015-01-01

    This series of three practical sessions centers on drugs that inhibit the enzyme acetylcholineesterase. This enzyme is responsible for the inactivation of acetylcholine and has been the target of drugs to treat glaucoma and Alzheimer's disease and for a number of insecticides and warfare agents. These sessions relate to a series of carbamate…

  4. The Dis-Art Creative Journey, Art Therapy for Persons with Disabilities: Adaptation of the Creative Journey

    ERIC Educational Resources Information Center

    Luzzatto, Paola; Bruno, Teresa; Cosco, Marianna; Del Curatolo, Annamaria; Frigenti, Franca; Macchioni, Silvia

    2017-01-01

    This article describes a 10-session group art therapy program for people with physical and neurological disabilities. This program, the DIS-ART Creative Journey, was adapted from the Creative Journey used with cancer patients, and was tested in Italy by 4 art therapists. The 5-step structure of each session and the 10 facilitating techniques used…

  5. NASA Space Biology Program. Eighth annual symposium's program and abstracts

    NASA Technical Reports Server (NTRS)

    Halstead, T. W. (Editor)

    1984-01-01

    The activities included five half days of presentations by space biology principal investigators, an evening of poster session presentations by research associates, and an afternoon session devoted to the Flight Experiments Program. Areas of discussion included the following: gravity receptor mechanisms; physiological effects of gravity, structural mass; fluid dynamics and metabolism; mechanisms of plant response; and the role of gravity in development.

  6. Space Solar Power Technical Interchange Meeting 2: SSP TIM 2

    NASA Technical Reports Server (NTRS)

    Sanders, Jim; Hawk, Clark W.

    1998-01-01

    The 2nd Space Solar Power Technical Interchange Meeting (SSP TIM 2) was conducted September 21st through 24th with the first part consisting of a Plenary session. The summary results of this Plenary session are contained in part one of this report. The attendees were then organized into Working Breakout Sessions and Integrated Product Team (IPT) Sessions for the purpose of conducting in-depth discussions in specific topic areas and developing a consensus as to appropriate study plans and actions to be taken. The Second part covers the Plenary Summary Session, which contains the summary results of the Working Breakout Sessions and IPT Sessions. The appendix contains the list of attendees. The ob'jective was to provide an update for the study teams and develop plans for subsequent study activities. This SSP TIM 2 was initiated and the results reported electronically over the Internet. The International Space Station (ISS) could provide the following opportunities for conducting research and technology (R&T) which are applicable to SSP: (1) Automation and Robotics, (2) Advanced Power Generation, (3) Advanced Power Management & Distribution (PMAD), (4) Communications Systems and Networks, (5) Energy Storage, (6) In Space Propulsion (ISP), (7) Structural Dynamics and Control, and Assembly and (8) Wireless Power Transmission.

  7. Professional efficiencies for diagnostic imaging services rendered by different physicians: analysis of recent medicare multiple procedure payment reduction policy.

    PubMed

    Duszak, Richard; Silva, Ezequiel; Kim, Angela J; Barr, Robert M; Donovan, William D; Kassing, Pamela; McGinty, Geraldine; Allen, Bibb

    2013-09-01

    The aim of this study was to quantify potential physician work efficiencies and appropriate multiple procedure payment reductions for different same-session diagnostic imaging studies interpreted by different physicians in the same group practice. Medicare Resource-Based Relative Value Scale data were analyzed to determine the relative contributions of various preservice, intraservice, and postservice physician diagnostic imaging work activities. An expert panel quantified potential duplications in professional work activities when separate examinations were performed during the same session by different physicians within the same group practice. Maximum potential work duplications for various imaging modalities were calculated and compared with those used as the basis of CMS payment policy. No potential intraservice work duplication was identified when different examination interpretations were rendered by different physicians in the same group practice. When multiple interpretations within the same modality were rendered by different physicians, maximum potential duplicated preservice and postservice activities ranged from 5% (radiography, fluoroscopy, and nuclear medicine) to 13.6% (CT). Maximum mean potential duplicated work relative value units ranged from 0.0049 (radiography and fluoroscopy) to 0.0413 (CT). This equates to overall potential total work reductions ranging from 1.39% (nuclear medicine) to 2.73% (CT). Across all modalities, this corresponds to maximum Medicare professional component physician fee reductions of 1.23 ± 0.38% (range, 0.95%-1.87%) for services within the same modality, much less than an order of magnitude smaller than those implemented by CMS. For services from different modalities, potential duplications were too small to quantify. Although potential efficiencies exist in physician preservice and postservice work when same-session, same-modality imaging services are rendered by different physicians in the same group practice, these are relatively minuscule and have been grossly overestimated by current CMS payment policy. Greater transparency and methodologic rigor in government payment policy development are warranted. Copyright © 2013 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  8. Ask Questions to Encourage Questions Asked

    ERIC Educational Resources Information Center

    belcastro, sarah-marie

    2017-01-01

    We delineate some types of structured practice (modeling, requests, feedback, and space-making) that help students learn to pose appropriate questions and to initiate exploration of those questions. Developing skills requires practice, so we suggest ways to embed structured practice into existing class sessions. Including structured practice is…

  9. [Training of residents in obstetrics and gynecology: Assessment of an educational program including formal lectures and practical sessions using simulators].

    PubMed

    Jordan, A; El Haloui, O; Breaud, J; Chevalier, D; Antomarchi, J; Bongain, A; Boucoiran, I; Delotte, J

    2015-01-01

    Evaluate an educational program in the training of residents in gynecology-obstetrics (GO) with a theory session and a practical session on simulators and analyze their learning curve. Single-center prospective study, at the university hospital (CHU). Two-day sessions were leaded in April and July 2013. An evaluation on obstetric and gynecological surgery simulator was available to all residents. Theoretical knowledge principles of obstetrics were evaluated early in the session and after formal lectures was taught to them. At the end of the first session, a satisfaction questionnaire was distributed to all participants. Twenty residents agreed to participate to the training sessions. Evaluation of theoretical knowledge: at the end of the session, the residents obtained a significant improvement in their score on 20 testing knowledge. Obstetrical simulator: a statistically significant improvement in scores on assessments simulator vaginal delivery between the first and second session. Subjectively, a larger increase feeling was seen after breech delivery simulation than for the cephalic vaginal delivery. However, the confidence level of the resident after breech delivery simulation has not been improved at the end of the second session. Simulation in gynecological surgery: a trend towards improvement in the time realized on the peg-transfer between the two sessions was noted. In the virtual simulation, no statistically significant differences showed, no improvement for in salpingectomy's time. Subjectively, the residents felt an increase in the precision of their gesture. Satisfaction: All residents have tried the whole program. They considered the pursuit of these sessions on simulators was necessary and even mandatory. The approach chosen by this structured educational program allowed a progression for the residents, both objectively and subjectively. This simulation program type for the resident's training would use this tool in assessing their skills and develop learning curves. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  10. PREFACE: SPIN2010 - Preface for Conference Proceedings

    NASA Astrophysics Data System (ADS)

    Ströher, Hans; Rathmann, Frank

    2011-03-01

    SPIN2010, the 19th International Spin Physics Symposium, took place between 27 September and 2 October, 2010 on the campus of Forschungszentrum Jülich GmbH (FZJ) in Jülich, Germany. The scientific program of this Symposium included many topics related to spin phenomena in particle and nuclear physics as well as those in related fields. The International Spin Physics Symposium series has combined the High Energy Spin Symposia and the Nuclear Polarization Conferences since 2000. The most recent two Symposia were held in Virginia, USA (October 2008) and in Kyoto, Japan (October 2006). The meeting was opened by the chairman of the Board of Management of Jülich Forschungszentrum, Professor Achim Bachem, who cordially welcomed the participants from all over the world and gave a brief introduction to the Center and the research conducted there. The scientific program consisted of plenary sessions and parallel sessions and included the following topics: Fundamental symmetries and spin Spin structure of hadrons Spin physics beyond the Standard Model Spin in hadronic reactions Spin physics with photons and leptons Spin physics in nuclear reactions and nuclei Acceleration, storage, and polarimetry of polarized beams Polarized ion and lepton sources and targets Future facilities and experiments Medical and technological applications of spin physics The 6-day symposium had about 300 participants. In total 35 plenary talks (including 3 summaries of other spin physics meetings) and 163 contributed talks were given. The contents of many of these can be found in the present contributions, arranged according to the above topics and the time sequence. In addition, a public lecture on "Drall in der Quantenwelt", presented by H O Meyer (Bloomington) was received very well. Participants had the option to visit the Cooler synchrotron COSY at the Nuclear Physics Institute (IKP) and the 9.4 T MRT-PET hybrid scanner at the Institute of Neuroscience and Medicine (INM), two unique facilities at FZJ, and many made the most of the opportunity. We gratefully acknowledge the financial support from Brookhaven National Laboratory (BNL, USA), Forschungszentrum Jülich (FZJ), the International Union of Pure And Applied Physics (IUPAP), Thomas Jefferson Laboratory (JLab, USA), Helmholtz Institute Mainz (HIM, Germany) and the Virtual Institute on Spin and Strong QCD (VI-QCD) of the Helmholtz Association (HGF). We would also like to thank the local people from IKP and other institutions of FZJ for their contributions and help - without them we would not have been able to organize this great meeting. The current proceedings comprise written contributions of many of the presentations during SPIN2010; however, due to the recent incident in Japan, a number of our colleagues from there were unfortunately not able to deliver their write-ups in due time. This volume was edited by Ralf Gebel, Christoph Hanhart, Andro Kacharava, Andreas Lehrach, Bernd Lorentz, Nikolai N Nikolaev, Andreas Nogga, Frank Rathmann, and Hans Ströher. The next symposium - SPIN2012 - will be held at the Joint Institute for Nuclear Research (JINR) in Dubna (Russia) in 2012. We are looking forward to meeting you there. Important conference-related links: SPIN2010 Web-site: https://www.congressa.de/SPIN2010/ Article in CERN Courier: http://cerncourier.com/cws/article/cern/45451 Spin Physics Committee: http://www.spin-community.org Jülich, April 2011 - Hans Ströher, Frank Rathmann (Chairs SPIN2010) Conference photograph

  11. The Guardian: The Source for Antiterrorism Information. Volume 9, Number 1, April 2007

    DTIC Science & Technology

    2007-04-01

    the fuel in these research reactors is generally not highly radioactive . Unlike the fuel rods in a nuclear power plant, these fuel elements would...NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND...practices and lessons learned. In addition, we will include Service and issue-specific breakout sessions that will focus on critical AT program elements

  12. A DATA ACQUISITION SYSTEM FOR THE STUDY OF TRANSIENT RADIATION EFFECTS ON ELECTRONIC DEVICES. Paper 5 of FOURTH RADIATION EFFECTS SYMPOSIUM, SEPTEMBER 15-16, 1959, CINCINNATI, OHIO. GENERAL SESSION PAPERS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cochrane, D.O.; Graham, F.E.; Sauer, H.S.

    1961-10-31

    ning both the transient and permanent effects that an environment of the type created by a nuclear detonation or a pulsed reactor exerts on electronic devices, is described. The design of suitable test heads for containing the electronic devices is discussed. The design of a blockhouse for use near Ground Sero when evaluating components in a weapons environment is also discussed. (C.J.G.)

  13. Changing Nuclear Landscape and Unique PML Structures During Early Epigenetic Transitions of Human Embryonic Stem Cells

    PubMed Central

    Butler, John T.; Hall, Lisa L.; Smith, Kelly P.; Lawrence, Jeanne B.

    2010-01-01

    The complex nuclear structure of somatic cells is important to epigenomic regulation, yet little is known about nuclear organization of human embryonic stem cells (hESC). Here we surveyed several nuclear structures in pluripotent and transitioning hESC. Observations of centromeres, telomeres, SC35 speckles, Cajal Bodies, lamin A/C and emerin, nuclear shape and size demonstrate a very different “nuclear landscape” in hESC. This landscape is remodeled during a brief transitional window, concomitant with or just prior to differentiation onset. Notably, hESC initially contain abundant signal for spliceosome assembly factor, SC35, but lack discrete SC35 domains; these form as cells begin to specialize, likely reflecting cell-type specific genomic organization. Concomitantly, nuclear size increases and shape changes as lamin A/C and emerin incorporate into the lamina. During this brief window, hESC exhibit dramatically different PML-defined structures, which in somatic cells are linked to gene regulation and cancer. Unlike the numerous, spherical somatic PML bodies, hES cells often display ~1–3 large PML structures of two morphological types: long linear “rods” or elaborate “rosettes”, which lack substantial SUMO-1, Daxx, and Sp100.These occur primarily between Day 0–2 of differentiation and become rare thereafter. PML rods may be “taut” between other structures, such as centromeres, but clearly show some relationship with the lamina, where PML often abuts or fills a “gap” in early lamin A/C staining. Findings demonstrate that pluripotent hES cells have a markedly different overall nuclear architecture, remodeling of which is linked to early epigenomic programming and involves formation of unique PML-defined structures. PMID:19449340

  14. Transportation Beyond 2000: Technologies Needed for Engineering Design

    NASA Technical Reports Server (NTRS)

    Huebner, Lawrence D. (Compiler); Asbury, Scott C. (Compiler); Lamar, John E. (Compiler); McKinley, Robert E., Jr. (Compiler); Scott, Robert C. (Compiler); Small, William J. (Compiler); Torres, Abel O. (Compiler)

    1996-01-01

    The purpose of the workshop was to acquaint the staff of the NASA Langley Research Center with the broad spectrum of transportation challenges and concepts foreseen within the next 20 years. The hope is that material presented at the workshop and contained in this document will stimulate innovative high-payoff research directed towards the efficiency of future transportation systems. The workshop included five sessions designed to stress the factors that will lead to a revolution in the way we will travel in the 21st century. The first session provides the historical background and a general perspective for future transportation, including emerging transportation alternatives such as working at a distance. Personal travel is the subject of Session Two. The third session looks at mass transportation, including advanced rail vehicles, advanced commuter aircraft, and advanced transport aircraft. The fourth session addresses some of the technologies required for the above revolutionary transportation systems to evolve. The workshop concluded with a wrap-up panel discussion, Session Five. The topics presented herein all have viable technical components and are at a stage in their development that, with sufficient engineering research, one or more of these could make a significant impact on transportation and our social structure.

  15. Transportation Beyond 2000: Technologies Needed for Engineering Design

    NASA Technical Reports Server (NTRS)

    Huebner, Lawrence D. (Compiler); Asbury, Scott C. (Compiler); Lamar, John E. (Compiler); McKinley, Robert E., Jr. (Compiler); Scott, Robert C. (Compiler); Small, William J. (Compiler); Torres, Abel O. (Compiler)

    1996-01-01

    The purpose of the workshop was to acquaint the staff of the NASA Langley Research Center with the broad spectrum of transportation challenges and concepts foreseen within the next 20 years. The hope is that the material presented at the workshop and contained in this document will stimulate innovative high-payoff research directed towards the efficiency of future transportation systems. The workshop included five sessions designed to stress the factors that will lead to a revolution in the way we will travel in the 21st century. The first session provides the historical background and a general perspective for future transportation, including emerging transportation alternatives such as working at a distance. Personal travel is the subject of Session Two. The third session looks at mass transportation, including advanced rail vehicles, advanced commuter aircraft, and advanced transport aircraft. The fourth session addresses some of the technologies required for the above revolutionary transportation systems to evolve. The workshop concluded with a wrap-up panel discussion, Session Five. The topics presented herein all have viable technical components and are at a stage in their development that, with sufficient engineering research, one or more of these could make a significant impact on transportation and our social structure.

  16. A framework for the etiology of running-related injuries.

    PubMed

    Bertelsen, M L; Hulme, A; Petersen, J; Brund, R K; Sørensen, H; Finch, C F; Parner, E T; Nielsen, R O

    2017-11-01

    The etiology of running-related injury is important to consider as the effectiveness of a given running-related injury prevention intervention is dependent on whether etiologic factors are readily modifiable and consistent with a biologically plausible causal mechanism. Therefore, the purpose of the present article was to present an evidence-informed conceptual framework outlining the multifactorial nature of running-related injury etiology. In the framework, four mutually exclusive parts are presented: (a) Structure-specific capacity when entering a running session; (b) structure-specific cumulative load per running session; (c) reduction in the structure-specific capacity during a running session; and (d) exceeding the structure-specific capacity. The framework can then be used to inform the design of future running-related injury prevention studies, including the formation of research questions and hypotheses, as well as the monitoring of participation-related and non-participation-related exposures. In addition, future research applications should focus on addressing how changes in one or more exposures influence the risk of running-related injury. This necessitates the investigation of how different factors affect the structure-specific load and/or the load capacity, and the dose-response relationship between running participation and injury risk. Ultimately, this direction allows researchers to move beyond traditional risk factor identification to produce research findings that are not only reliably reported in terms of the observed cause-effect association, but also translatable in practice. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  17. Effects of basic clinical skills training on objective structured clinical examination performance.

    PubMed

    Jünger, Jana; Schäfer, Sybille; Roth, Christiane; Schellberg, Dieter; Friedman Ben-David, Miriam; Nikendei, Christoph

    2005-10-01

    The aim of curriculum reform in medical education is to improve students' clinical and communication skills. However, there are contradicting results regarding the effectiveness of such reforms. A study of internal medicine students was carried out using a static group design. The experimental group consisted of 77 students participating in 7 sessions of communication training, 7 sessions of skills-laboratory training and 7 sessions of bedside-teaching, each lasting 1.5 hours. The control group of 66 students from the traditional curriculum participated in equally as many sessions but was offered only bedside teaching. Students' cognitive and practical skills performance was assessed using Multiple Choice Question (MCQ) testing and an objective structured clinical examination (OSCE), delivered by examiners blind to group membership. The experimental group performed significantly better on the OSCE than did the control group (P < 0.01), whereas the groups did not differ on the MCQ test (P < 0.15). This indicates that specific training in communication and basic clinical skills enabled students to perform better in an OSCE, whereas its effects on knowledge did not differ from those of the traditional curriculum. Curriculum reform promoting communication and basic clinical skills are effective and lead to an improved performance in history taking and physical examination skills.

  18. FROM THE HISTORY OF PHYSICS: The nuclear shield in the 'thirty-year war' of physicists against ignorant criticism of modern physical theories

    NASA Astrophysics Data System (ADS)

    Vizgin, Vladimir P.

    1999-12-01

    This article deals with the almost 'thirty-year war' led by physicists against the authorities' incompetent philosophical and ideological interference with science. The 'war' is shown to have been related to the history of Soviet nuclear weapons. Theoretical milestones of 20th century physics, to wit, theory of relativity and quantum mechanics, suffered endless 'attacks on philosophical grounds'. The theories were proclaimed idealistic as well as unduly abstract and out of touch with practice; their authors and followers were labelled 'physical idealists', and later, in the 1940s and 1950s, even 'cosmopolitans without kith or kin'. Meanwhile, quantum and relativistic theories, as is widely known, had become the basis of nuclear physics and of the means of studying the atomic nucleus (charged particle accelerators, for instance). The two theories thus served, to a great extent, as a basis for both peaceful and military uses of nuclear energy, made possible by the discovery of uranium nuclear fission under the action of neutrons. In the first part, the article recounts how prominent physicists led the way to resisting philosophical and ideological pressure and standing up for relativity, quantum theories and nuclear physics, thus enabling the launch of the atomic project. The second part contains extensive material proving the point that physicists effectively used the 'nuclear shield' in the 1940s and 1950s against the 'philosophical-cosmopolitan' pressure, indeed saving physics from a tragic fate as that of biology at the Academy of Agricultural Sciences (VASKhNIL) session in 1948.

  19. Structural basis for the regulation of nuclear import of Epstein-Barr virus nuclear antigen 1 (EBNA1) by phosphorylation of the nuclear localization signal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nakada, Ryohei; Hirano, Hidemi; Structural Biology Research Center, Graduate School of Science, Nagoya University

    Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is expressed in every EBV-positive tumor and is essential for the maintenance, replication, and transcription of the EBV genome in the nucleus of host cells. EBNA1 is a serine phosphoprotein, and it has been shown that phosphorylation of S385 in the nuclear localization signal (NLS) of EBNA1 increases the binding affinity to the nuclear import adaptor importin-α1 as well as importin-α5, and stimulates nuclear import of EBNA1. To gain insights into how phosphorylation of the EBNA1 NLS regulates nuclear import, we have determined the crystal structures of two peptide complexes of importin-α1: onemore » with S385-phosphorylated EBNA1 NLS peptide, determined at 2.0 Å resolution, and one with non-phosphorylated EBNA1 NLS peptide, determined at 2.2 Å resolution. The structures show that EBNA1 NLS binds to the major and minor NLS-binding sites of importin-α1, and indicate that the binding affinity of the EBNA1 NLS to the minor NLS-binding site could be enhanced by phosphorylation of S385 through electrostatic interaction between the phosphate group of phospho-S385 and K392 of importin-α1 (corresponding to R395 of importin-α5) on armadillo repeat 8. - Highlights: • Nuclear import of EBNA1 can be regulated by phosphorylation of NLS. • Crystal structures of importin-α1 bound to the NLS peptides of EBNA1 are solved. • Structures provide insights into how phosphorylation can regulate nuclear import.« less

  20. Modular fabrication and characterization of complex silicon carbide composite structures Advanced Reactor Technologies (ART) Research Final Report (Feb 2015 – May 2017)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Khalifa, Hesham

    Advanced ceramic materials exhibit properties that enable safety and fuel cycle efficiency improvements in advanced nuclear reactors. In order to fully exploit these desirable properties, new processing techniques are required to produce the complex geometries inherent to nuclear fuel assemblies and support structures. Through this project, the state of complex SiC-SiC composite fabrication for nuclear components has advanced significantly. New methods to produce complex SiC-SiC composite structures have been demonstrated in the form factors needed for in-core structural components in advanced high temperature nuclear reactors. Advanced characterization techniques have been employed to demonstrate that these complex SiC-SiC composite structures providemore » the strength, toughness and hermeticity required for service in harsh reactor conditions. The complex structures produced in this project represent a significant step forward in leveraging the excellent high temperature strength, resistance to neutron induced damage, and low neutron cross section of silicon carbide in nuclear applications.« less

  1. FOREWORD: VI Workshop in Electron Volt Neutron Spectroscopy: Frontiers and Horizons

    NASA Astrophysics Data System (ADS)

    Seel, A. G.; Senesi, R.; Fernandez-Alonso, F.

    2014-12-01

    January 2014 saw the congregation in Abingdon (UK) of scientists from across the world, to discuss the current state and future of spectroscopy using epithermal neutrons. This meeting was the sixth in a series of workshops held in collaboration between the Science and Technology Facilities Council (UK) and the Consiglio Nazionale delle Ricerche (Italy), aimed at bringing together researchers with an interest in the use of electron-volt neutrons in spectroscopic studies [1]. This technique is termed Deep Inelastic Neutron Scattering (DINS), and also Neutron Compton Scattering (NCS) in reference to the analogy with Compton scattering of X-rays from electrons. In particular, this meeting centred jointly around experimentalists and theoreticians, formulating animated discussions as to the current overview of DINS and future horizons facing the field. The use of electron Volt neutrons for spectroscopic measurements dates back to the advent of proton-driven spallation neutron sources in the 1970s and 1980s. Following an initial scientific meeting in Los Alamos (USA) [2], the first two meetings in this series were held in Abingdon (UK) in 1995 and 1998, with subsequent meetings held in Santa Fe (USA) in 2005 [3], Oak Ridge National Laboratory (USA) in 2006 [4], and Rome, Italy; in 2010 [5]. The flagship instrument serving a continual user-programme for DINS measurements, and the main focus of this meeting, has been the VESUVIO spectrometer at ISIS [6, 7]. Subsequent instruments like SEQUOIA in the USA [8, 9] and a newer spectrometer in the Bariloche LINAC in Argentina [10, 11] have also been commissioned and began serving a growing user community. The availability of DINS measurements has extended the range of possible spectroscopic techniques that utilise neutrons into the kinematic region of high energy and momentum transfers, shown schematically in Figure 1. Spectroscopic instrument suites such as that of ISIS are thus able to probe processes on timescales across nine orders of magnitude, from quantum tunnelling and molecular diffusion up to nuclear recoil under the impulse approximation. DINS is one of the most direct techniques for probing nuclear quantum dynamics in condensed matter, with the ability to measure nuclear kinetic energies and momentum distributions of light nuclei. A major theme for current DINS research relates to the study of nuclear quantum effects, particularly regarding the non-classical behaviour of hydrogen or deuterium. This emphasis was reflected by the meeting's opening session dealing with the measurement of momentum distributions in hydrogen-bonded and aqueous systems (see Table 1). Whilst concentrating on experimental studies, data were presented from the outset alongside state-of-the-art path-integral molecular dynamics (PIMD) calculations, affording an animated discussion as to the interpretation of measured neutron Compton profiles in spatially disordered systems. The extension of DINS to heavier nuclei was visited in the second session of the meeting, under the over-arching theme of MAss-selective Neutron SpEctroscopy (MANSE). The ability of DINS to examine atomically distinct species in condensed matter has garnered interest from the chemistry and materials communities, with both binary systems and more complex materials being presented in this session. Nuclei of interest in applied materials research were highlighted, including oxygen, lithium and fluorine, alongside an assessment of current capabilities and future developments in their examination by DINS. The concluding session of the first day of the meeting was concerned with instrumentation. The detection of epithermal neutrons requires technologies unique relative to their lower-energy counterparts, and the first talk of this session outlined how detector capabilities on existing instruments has been revolutionised in recent years. Resonance detectors and techniques involving analyser-foil cycling were detailed, explaining how they have improved not only the count-rate but also the spectral resolution of instruments such as VESUVIO. Beyond NCS, the detection of nuclear resonances were also considered. An overview of VESUVIO (a time-of-flight instrument operating in so-called indirect geometry) was then given, alongside ways it could be improved upon in light of growing demands from the user community. This discussion was complemented by a presentation of the use of direct-geometry instruments such as SEQUOIA for DINS measurements, highlighting the complementarity with parallel studies on VESUVIO. The second day of the meeting was given over to the theoretical aspects of nuclear momentum distributions. Delegates were presented with the manner in which we can computationally incorporate nuclear quantum effects, along with their output in terms of 'measureables', relating to a varied range of systems. Results were presented from hydrogen-bonded liquids, ferroelectric materials, biological systems, and mixed bosonic-fermionic calculations. The ability to now approach experimental measurement with theoretical insight, and vice versa, is a sea-change in research into nuclear quantum effects. This field is a high-profile area in chemical physics and materials research, and a concerted approach by theory and experimentation allows us to explore and explain the dynamical state of matter at the atomic level in a manner previously unobtainable. Concluding each session throughout the meeting were periods of open discussion, wherein all present could comment or expand upon themes arising from the preceding talks. These discussions were then further distilled and clarified during the final section of the meeting, the 'Frontiers and Horizons' discussion, open to all present to delineate the next steps in DINS as a whole. Experimentalists and theoreticians were able to present their views on how each community could move forward to complement each other, not only separately but with specific projects and milestones in mind. These discussions have been included within these proceedings to highlight the future outlook of DINS. It is the hope of these editors that this meeting will allow spectroscopy with epithermal neutrons to further develop, explaining the very quantum nature of dynamics in condensed matter. Bringing together, as it did, international researchers in fields at the frontiers of their respective experimental and theoretical communities, we hope that the next meeting in this series will see the fruition of concepts and projects instigated by this one.

  2. A call for action on disarmament and population.

    PubMed

    Fukuda, T

    1994-08-01

    Takeo Fukuda, former prime minister of Japan, opened the 12th session of the InterAction Council in Dresden, Germany, with a speech on June 7, 1994. The council has three priority concerns: world peace and disarmament; global problems of population increase, environmental degradation, resource and energy questions; and the question of activating the world economy. The cold war structure has crumbled, but stockpiled nuclear weapons still pose a threat to the world. Under such a situation, the role of multilateral organizations, particularly the UN, has become increasingly important. The world's political management henceforth should encompass North-South-East-West, the entire world, and multilateral institutions should be further strengthened. Special attention should be paid to the neglected North-South relations. The emergence of the mass-consumption society has generated the era of finite resources and environment. The rapidly increasing global population further complicates this issue. Unless the global problems of population, environment, resources, and energy are alleviated, the future for posterity is dubious. The population of the world is increasing by 100 million each year. It was 1.6 billion at the beginning of this century, but it is expected to increase to 6.4 billion at the end of the century, to 8 billion by the year 2020, and to 10 billion by 2050. Resources, energy, environment, and global population are mutually linked; the problem of balancing the rapidly increasing population and the food supply must be addressed. The hope is that the Food and Agriculture Organization will come up with measures to cope with this problem by forecasting the food supply and demand and population. The InterAction Council will hold its 13th session in Tokyo in 1995.

  3. The intriguing plant nuclear lamina.

    PubMed

    Ciska, Malgorzata; Moreno Díaz de la Espina, Susana

    2014-01-01

    The nuclear lamina is a complex protein mesh attached to the inner nuclear membrane (INM), which is also associated with nuclear pore complexes. It provides mechanical support to the nucleus and nuclear envelope, and as well as facilitating the connection of the nucleoskeleton to the cytoskeleton, it is also involved in chromatin organization, gene regulation, and signaling. In metazoans, the nuclear lamina consists of a polymeric layer of lamins and other interacting proteins responsible for its association with the INM and chromatin. In plants, field emission scanning electron microscopy of nuclei, and thin section transmission electron microscopy of isolated nucleoskeletons, reveals the lamina to have a similar structure to that of metazoans. Moreover, although plants lack lamin genes and the genes encoding most lamin-binding proteins, the main functions of the lamina are fulfilled in plants. Hence, it would appear that the plant lamina is not based on lamins and that other proteins substitute for lamins in plant cells. The nuclear matrix constituent proteins are the best characterized structural proteins in the plant lamina. Although these proteins do not display strong sequence similarity to lamins, their predicted secondary structure and sub-nuclear distribution, as well as their influence on nuclear size and shape, and on heterochromatin organization, suggest they could be functional lamin analogs. In this review we shall summarize what is currently known about the organization and composition of the plant nuclear lamina and its interacting complexes, and we will discuss the activity of this structure in the plant cell and its nucleus.

  4. Vibrational Properties of Hydrogen-Bonded Systems Using the Multireference Generalization to the "On-the-Fly" Electronic Structure within Quantum Wavepacket ab Initio Molecular Dynamics (QWAIMD).

    PubMed

    Li, Junjie; Li, Xiaohu; Iyengar, Srinivasan S

    2014-06-10

    We discuss a multiconfigurational treatment of the "on-the-fly" electronic structure within the quantum wavepacket ab initio molecular dynamics (QWAIMD) method for coupled treatment of quantum nuclear effects with electronic structural effects. Here, multiple single-particle electronic density matrices are simultaneously propagated with a quantum nuclear wavepacket and other classical nuclear degrees of freedom. The multiple density matrices are coupled through a nonorthogonal configuration interaction (NOCI) procedure to construct the instantaneous potential surface. An adaptive-mesh-guided set of basis functions composed of Gaussian primitives are used to simplify the electronic structure calculations. Specifically, with the replacement of the atom-centered basis functions positioned on the centers of the quantum-mechanically treated nuclei by a mesh-guided band of basis functions, the two-electron integrals used to compute the electronic structure potential surface become independent of the quantum nuclear variable and hence reusable along the entire Cartesian grid representing the quantum nuclear coordinates. This reduces the computational complexity involved in obtaining a potential surface and facilitates the interpretation of the individual density matrices as representative diabatic states. The parametric nuclear position dependence of the diabatic states is evaluated at the initial time-step using a Shannon-entropy-based sampling function that depends on an approximation to the quantum nuclear wavepacket and the potential surface. This development is meant as a precursor to an on-the-fly fully multireference electronic structure procedure embedded, on-the-fly, within a quantum nuclear dynamics formalism. We benchmark the current development by computing structural, dynamic, and spectroscopic features for a series of bihalide hydrogen-bonded systems: FHF(-), ClHCl(-), BrHBr(-), and BrHCl(-). We find that the donor-acceptor structural features are in good agreement with experiments. Spectroscopic features are computed using a unified velocity/flux autocorrelation function and include vibrational fundamentals and combination bands. These agree well with experiments and other theories.

  5. The nuclear membrane-associated honeycomb structure of the unicellular organism Amoeba proteus: on the search for homologies with the nuclear lamina of metazoa.

    PubMed

    Schmidt, M; Grossmann, U; Krohne, G

    1995-07-01

    In the protozoon Amoeba proteus, a complex and highly organized structure with the morphology of a honeycomb is associated with the nucleoplasmic surface of the nuclear membrane. We have tested whether this structure exhibits similarity to the nuclear lamina of metazoic organisms. First, we have shown that the honeycomb layer is composed of 3 to 5 nm thick protein fibrils resistant to treatment with detergent, high salt, and digestion with nucleases, thus possessing properties typical for karyoskeletal elements. However, in contrast to the meshwork of lamin filaments in somatic cells of metazoic organisms, the honeycomb layer is not tightly anchored to the nucleoplasmic side of pore complexes, or to the inner nuclear membrane. Second, in microinjection experiments we investigated whether fluorescently labeled lamins of Xenopus laevis (lamins A and LI) and Drosophila melanogaster (lamin Dmo) were able to associate in vivo with the Amoeba proteus honeycomb structure. In microinjected amoeba these three lamins were efficiently transported into the nucleus, but did not associate with the nuclear envelope. Our results suggest that the Amoeba proteus nuclear envelope, including the honeycomb layer, does not contain proteins exhibiting high homologies to lamins of metazoan species thus preventing the localized assembly of microinjected lamins along the nuclear periphery.

  6. Mid-Task Break Improves Global Integration of Functional Connectivity in Lower Alpha Band

    PubMed Central

    Li, Junhua; Lim, Julian; Chen, Yu; Wong, Kianfoong; Thakor, Nitish; Bezerianos, Anastasios; Sun, Yu

    2016-01-01

    Numerous efforts have been devoted to revealing neurophysiological mechanisms of mental fatigue, aiming to find an effective way to reduce the undesirable fatigue-related outcomes. Until recently, mental fatigue is thought to be related to functional dysconnectivity among brain regions. However, the topological representation of brain functional connectivity altered by mental fatigue is only beginning to be revealed. In the current study, we applied a graph theoretical approach to analyse such topological alterations in the lower alpha band (8~10 Hz) of EEG data from 20 subjects undergoing a two-session experiment, in which one session includes four successive blocks with visual oddball tasks (session 1) whereas a mid-task break was introduced in the middle of four task blocks in the other session (session 2). Phase lag index (PLI) was then employed to measure functional connectivity strengths for all pairs of EEG channels. Behavior and connectivity maps were compared between the first and last task blocks in both sessions. Inverse efficiency scores (IES = reaction time/response accuracy) were significantly increased in the last task block, showing a clear effect of time-on-task in participants. Furthermore, a significant block-by-session interaction was revealed in the IES, suggesting the effectiveness of the mid-task break on maintaining task performance. More importantly, a significant session-independent deficit of global integration and an increase of local segregation were found in the last task block across both sessions, providing further support for the presence of a reshaped topology in functional brain connectivity networks under fatigue state. Moreover, a significant block-by-session interaction was revealed in the characteristic path length, small-worldness, and global efficiency, attributing to the significantly disrupted network topology in session 1 in comparison of the maintained network structure in session 2. Specifically, we found increased nodal betweenness centrality in several channels resided in frontal regions in session 1, resembling the observations of more segregated global architecture under fatigue state. Taken together, our findings provide insights into the substrates of brain functional dysconnectivity patterns for mental fatigue and reiterate the effectiveness of the mid-task break on maintaining brain network efficiency. PMID:27378894

  7. NNDC Tools and Publications

    Science.gov Websites

    Site Index NNDC Tools and Publications Nuclear Structure and Decay Tools Nuclear Reaction Tools Nuclear Structure and Decay Tools 2016 Atomic Mass Evaluation Atomic mass evaluation, by Wang, Audi values as a function of gamma energy and multipolarity. Calculations based on I.M. Band and S. Raman

  8. 76 FR 74831 - Aging Management of Stainless Steel Structures and Components in Treated Borated Water

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-01

    ... exposed to treated borated water. In response to a request from the Nuclear Energy Institute (NEI), the... NUCLEAR REGULATORY COMMISSION [NRC-2011-0256] Aging Management of Stainless Steel Structures and Components in Treated Borated Water AGENCY: Nuclear Regulatory Commission. ACTION: Draft interim staff...

  9. H. R. 3743: This Act may be cited as the Iran Nuclear Proliferation Prevention Act of 1998, Introduced in the House of Representatives, One Hundred Fifth Congress, Second Session, April 29, 1998

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1998-04-29

    The purpose of this bill is to withhold voluntary proportional assistance for programs and projects of the International Atomic Energy Agency relating to the development and completion of the Bushehr nuclear power plant in Iran, and for other purposes. This bill is divided into the following sections: Section 1. Short Title; Section 2. Findings; Section 3. Withholding of voluntary contributions to the International Atomic Energy Agency for programs and projects in Iran. Section 4. Annual review by Secretary of State of programs and projects of the International Atomic Energy Agency; United States opposition to programs and projects of the Agencymore » in Iran; Section 5. Reporting Requirements; and Section 7. Sense of the Congress.« less

  10. Anger Self-Management in Chronic Traumatic Brain Injury: Protocol for a Psycho-educational Treatment With a Structurally Equivalent Control and an Evaluation of Treatment Enactment

    PubMed Central

    Hart, Tessa; Brockway, Jo Ann; Fann, Jesse R.; Maiuro, Roland D.; Vaccaro, Monica J.

    2014-01-01

    Anger and irritability are important and persistent clinical problems following traumatic brain injury (TBI). Treatment options include medications, behavioral modification, and psychotherapies, but some are impractical and none have proven efficacy with this population. We describe a randomized multi-center clinical trial testing a novel, one-on-one, 8-session psychoeducational treatment program, Anger Self-Management Training (ASMT), designed specifically for people with TBI who have significant cognitive impairment. The trial is notable for its use of a structurally equivalent comparison treatment, called Personal Readjustment and Education (PRE), which was created for the study and is intended to maximize equipoise for both participants and treaters. Fidelity assessment is conducted in real time and used in therapist supervision sessions. The primary outcome is change in self-reported anger on validated measures from pre-treatment to 1 week after the final session. Secondary outcomes include participant anger as reported by a significant other; emotional distress in domains other than anger/ irritability; behavioral functioning; and quality of life. An interim assessment after the 4th session will allow examination of the trajectory of any observed treatment effects, and a follow-up assessment 2 months after the end of intervention will allow examination of persistence of effects. A treatment enactment phase, in which participants are interviewed several months after the last therapy session, is designed to provide qualitative data on whether and to what extent the principles and techniques learned in treatment are still carried out in daily life. PMID:25530306

  11. PREFACE: XXXV Symposium on Nuclear Physics

    NASA Astrophysics Data System (ADS)

    Padilla-Rodal, E.; Bijker, R.

    2012-09-01

    Conference logo The XXXV Symposium on Nuclear Physics was held at Hotel Hacienda Cocoyoc, Morelos, Mexico from January 3-6 2012. Conceived in 1978 as a small meeting, over the years and thanks to the efforts of various organizing committees, the symposium has become a well known international conference on nuclear physics. To the best of our knowledge, the Mexican Symposium on Nuclear Physics represents the conference series with longest tradition in Latin America and one of the longest-running annual nuclear physics conferences in the world. The Symposium brings together leading scientists from all around the world, working in the fields of nuclear structure, nuclear reactions, physics with radioactive ion beams, hadronic physics, nuclear astrophysics, neutron physics and relativistic heavy-ion physics. Its main goal is to provide a relaxed environment where the exchange of ideas, discussion of new results and consolidation of scientific collaboration are encouraged. To celebrate the 35th edition of the symposium 53 colleagues attended from diverse countries including: Argentina, Australia, Canada, Japan, Saudi Arabia and USA. We were happy to have the active participation of Eli F Aguilera, Eduardo Andrade, Octavio Castaños, Alfonso Mondragón, Stuart Pittel and Andrés Sandoval who also participated in the first edition of the Symposium back in 1978. We were joined by old friends of Cocoyoc (Stuart Pittel, Osvaldo Civitarese, Piet Van Isacker, Jerry Draayer and Alfredo Galindo-Uribarri) as well as several first time visitors that we hope will come back to this scientific meeting in the forthcoming years. The scientific program consisted of 33 invited talks, proposed by the international advisory committee, which nicely covered the topics of the Symposium giving a balanced perspective between the experimental and the theoretical work that is currently underway in each line of research. Fifteen posters complemented the scientific sessions giving the opportunity for Mexican students to present their current research and interact with the visiting scientists. The present volume contains 21 research articles based on invited talks presented at the symposium. We cannot thank enough to all the authors for their enthusiastic contribution, to the anonymous referees for the time they devoted to the review process, which helped us to maintain the high standard of the Conference Proceedings. Finally we would like to thank the International Advisory Committee and the Sponsoring Organizations that made this event possible. E Padilla-Rodal and R Bijker Editors Conference photograph International Advisory Committee Osvaldo Civitarese, Universidad Nacional de La Plata, Argentina Jerry P Draayer, Louisiana State University, USA Alfredo Galindo-Uribarri, Oak Ridge National Laboratory, USA Paulo Gomes, Universidade Federal Fluminense, Brazil Piet Van Isacker, GANIL, France James J Kolata, University of Notre Dame, USA Reiner Krücken, TRIUMF, Canada Jorge López, The University of Texas at El Paso, USA Stuart Pittel, University of Delaware, USA W Michael Snow, Indiana University, USA Adam Szczepaniak, Indiana University, USA Michael Wiescher, University of Notre Dame, USA Organizing Committee Elizabeth Padilla-Rodal (Chair), Instituto de Ciencias Nucleares, UNAM, Mexico Roelof Bijker, Instituto de Ciencias Nucleares, UNAM, Mexico Sponsoring Organizations División de Física Nuclear, SMF Dirección General de Asuntos de Personal Académico, UNAM Centro Latino-Americano de Física Instituto de Ciencias Nucleares, UNAM Instituto de Física, UNAM Instituto Nacional de Investigaciones Nucleares

  12. Nuclear transmutation in steels

    NASA Astrophysics Data System (ADS)

    Belozerova, A. R.; Shimanskii, G. A.; Belozerov, S. V.

    2009-05-01

    The investigations of the effects of nuclear transmutation in steels that are widely used in nuclear power and research reactors and in steels that are planned for the application in thermonuclear fusion plants, which are employed under the conditions of a prolonged action of neutron irradiation with different spectra, made it possible to study the effects of changes in the isotopic and chemical composition on the tendency of changes in the structural stability of these steels. For the computations of nuclear transmutation in steels, we used a program complex we have previously developed on the basis of algorithms for constructing branched block-type diagrams of nuclide transformations and for locally and globally optimizing these diagrams with the purpose of minimizing systematic errors in the calculation of nuclear transmutation. The dependences obtained were applied onto a Schaeffler diagram for steels used for structural elements of reactors. For the irradiation in fission reactors, we observed only a weak influence of the effects of nuclear transmutation in steels on their structural stability. On the contrary, in the case of irradiation with fusion neutrons, a strong influence of the effects of nuclear transmutation in steels on their structural stability has been noted.

  13. Structured didactic teaching sessions improve medical student neurology clerkship test scores: a pilot study.

    PubMed

    Menkes, Daniel L; Reed, Mary

    2008-01-01

    To determine the effectiveness of didactic case-based instruction methodology to improve medical student comprehension of common neurological illnesses and neurological emergencies. Neurology department, academic university. 415 third and fourth year medical students performing a required four week neurology clerkship. Raw test scores on a 1 hour, 50-item clinical vignette based examination and open-ended questions in a post-clerkship feedback session. There was a statistically significant improvement in overall test scores (p<0.001). Didactic teaching sessions have a significant positive impact on neurology student clerkship test score performance and perception of their educational experience. Confirmation of these results across multiple specialties in a multi-center trial is warranted.

  14. Control of nuclear β-dystroglycan content is crucial for the maintenance of nuclear envelope integrity and function.

    PubMed

    Vélez-Aguilera, Griselda; de Dios Gómez-López, Juan; Jiménez-Gutiérrez, Guadalupe E; Vásquez-Limeta, Alejandra; Laredo-Cisneros, Marco S; Gómez, Pablo; Winder, Steve J; Cisneros, Bulmaro

    2018-02-01

    β-Dystroglycan (β-DG) is a plasma membrane protein that has ability to target to the nuclear envelope (NE) to maintain nuclear architecture. Nevertheless, mechanisms controlling β-DG nuclear localization and the physiological consequences of a failure of trafficking are largely unknown. We show that β-DG has a nuclear export pathway in myoblasts that depends on the recognition of a nuclear export signal located in its transmembrane domain, by CRM1. Remarkably, NES mutations forced β-DG nuclear accumulation resulting in mislocalization and decreased levels of emerin and lamin B1 and disruption of various nuclear processes in which emerin (centrosome-nucleus linkage and β-catenin transcriptional activity) and lamin B1 (cell cycle progression and nucleoli structure) are critically involved. In addition to nuclear export, the lifespan of nuclear β-DG is restricted by its nuclear proteasomal degradation. Collectively our data show that control of nuclear β-DG content by the combination of CRM1 nuclear export and nuclear proteasome pathways is physiologically relevant to preserve proper NE structure and activity. Copyright © 2017 Elsevier B.V. All rights reserved.

  15. Stress perceptions of soldiers participating in training at the Chemical Defense Training Facility: The mediating effects of motivation, experience, and confidence level. Final report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Fatkin, L.T.; Hudgens, G.A.

    1994-01-01

    An investigation was conducted by the U.S. Army Research Laboratory (ARL) and funded by the Physiological and Psychological Effects of the Nuclear, Biological, and Chemical (NBC) Environment and Sustained Operations on Systems in Combat (P2NBC2) program to assess the psychological reactions of soldiers in mission-oriented protective posture (MOPP) IV participating in training in a simulated chemical agent environment and in a toxic agent environment. A total of 155 soldiers who participated in the basic course (junior enlisted) and the advanced courses (officer and noncommissioned officer NCO groups) as part of their military occupational specialty (MOS) training volunteered for the study.more » The junior enlisted group reported significant increases in anxiety during four sessions as they approached the toxic agent portion of the training. The more experienced groups showed a small, but significant increase in anxiety during sessions. Their level of hostility, a component of stress that usually relates to levels of personal frustration, decreased significantly from the time of their initial testing to just before the training began. Since the initial session occurred 1 to 2 weeks before the U.S. Army Chemical Defense Training Facility (CDTF) training, the elevated frustration level may be a reflection of their overall experiences within the intensive chemical defense training program. A significant drop in reported fatigue between the pre- and post-training sessions may indicate a certain level of vigilance gained by participating in the training.« less

  16. Lewis Structures Technology, 1988. Volume 1: Structural Dynamics

    NASA Technical Reports Server (NTRS)

    1988-01-01

    The specific purpose of the symposium was to familiarize the engineering structures community with the depth and range of research performed by the Structures Division of the Lewis Research Center and its academic and industrial partners. Sessions covered vibration control, fracture mechanics, ceramic component reliability, parallel computing, nondestructive testing, dynamical systems, fatigue and damage, wind turbines, hot section technology, structural mechanics codes, computational methods for dynamics, structural optimization, and applications of structural dynamics.

  17. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hudson, S.R.

    This report presents the results of a four-day symposium which reviewed the state-of-the-art, field testing and recent progress in underground coal conversion. The symposium was held at Keystone Lodge, Colorado, August 15-19, 1982, and was sponsored by the US Department of Energy and hosted by Sandia National Laboratories. Over 100 attendees participated in this seminar which offered more than 60 presentations in both poster and oral sessions on The Status of UCC Technology, Achievements and Problems of UCC, Future R and D Activities, and Roles and Outlooks, for an overall theme of Where Do We Go From Here. This symposiummore » was structured to deal with an evaluation of the present uncertainty in future federal funding of UCC. Panel discussions were held after each oral session to address this overall question. The final session of the symposium was a summary session reflecting the thoughts of all panelists and symposium speakers. This session also serves as our Executive Summary (page 567). Forty-one papers have been entered individually into EDB and ERA; twelve papers had been entered previously. (LTN)« less

  18. Evolution of Structure in Nuclei: Meditation by Sub-Shell Modifications and Relation to Binding Energies

    NASA Astrophysics Data System (ADS)

    Casten, R. F.; Cakirli, R. B.

    2009-03-01

    Understanding the development of configuration mixing, coherence, collectivity, and deformation in nuclei is one of the crucial challenges in nuclear structure physics, and one which has become all the more important with the advent of next generation facilities for the study of exotic nuclei. We will discuss recent work on phase/shape transitional behavior in nuclei, and the role of changes in sub-shell structure in mediating such transitional regions. We will also discuss a newly found, much deeper, link between nuclear structure and nuclear binding energies.

  19. Nuclear reactor apparatus

    DOEpatents

    Wade, Elman E.

    1978-01-01

    A lifting, rotating and sealing apparatus for nuclear reactors utilizing rotating plugs above the nuclear reactor core. This apparatus permits rotation of the plugs to provide under the plug refueling of a nuclear core. It also provides a means by which positive top core holddown can be utilized. Both of these operations are accomplished by means of the apparatus lifting the top core holddown structure off the nuclear core while stationary, and maintaining this structure in its elevated position during plug rotation. During both of these operations, the interface between the rotating member and its supporting member is sealingly maintained.

  20. Molecular dynamics for dense matter

    NASA Astrophysics Data System (ADS)

    Maruyama, Toshiki; Watanabe, Gentaro; Chiba, Satoshi

    2012-08-01

    We review a molecular dynamics method for nucleon many-body systems called quantum molecular dynamics (QMD), and our studies using this method. These studies address the structure and the dynamics of nuclear matter relevant to neutron star crusts, supernova cores, and heavy-ion collisions. A key advantage of QMD is that we can study dynamical processes of nucleon many-body systems without any assumptions about the nuclear structure. First, we focus on the inhomogeneous structures of low-density nuclear matter consisting not only of spherical nuclei but also of nuclear "pasta", i.e., rod-like and slab-like nuclei. We show that pasta phases can appear in the ground and equilibrium states of nuclear matter without assuming nuclear shape. Next, we show our simulation of compression of nuclear matter which corresponds to the collapsing stage of supernovae. With the increase in density, a crystalline solid of spherical nuclei changes to a triangular lattice of rods by connecting neighboring nuclei. Finally, we discuss fragment formation in expanding nuclear matter. Our results suggest that a generally accepted scenario based on the liquid-gas phase transition is not plausible at lower temperatures.

  1. Enthusiasm for homework and improvement of psychological distress in subthreshold depression during behavior therapy: secondary analysis of data from a randomized controlled trial.

    PubMed

    Hayasaka, Y; Furukawa, T A; Sozu, T; Imai, H; Kawakami, N; Horikoshi, M

    2015-11-25

    Cognitive behavioral therapy (CBT) usually involves homework, the completion of which is a known predictor of a positive outcome. The aim of the present study was to examine the session-by-session relationships between enthusiasm to complete the homework and the improvement of psychological distress in depressed people through the course of therapy. Working people with subthreshold depression were recruited to participate in the telephone CBT (tCBT) program with demonstrated effectiveness. Their enthusiasm for homework was enhanced with motivational interviewing techniques and was measured by asking two questions: "How strongly do you feel you want to do this homework?" and "How confident do you feel you can actually accomplish this homework?" at the end of each session. The outcome was the K6 score, which was administered at the start of each session. The K6 is an index of psychological distress including depression and anxiety. We used structural equation modeling (SEM) to elucidate the relationships between enthusiasm and the K6 scores from session to session. The best fitting model suggested that, throughout the course of behavior therapy (BT), enthusiasm to complete the homework was negatively correlated with the K6 scores for the subsequent session, while the K6 score measured at the beginning of the session did not influence the enthusiasm to complete the homeworks assigned for that session. Empirical data now support the practitioners of BT when they try to enhance their patient's enthusiasm for homework regardless of the participant's distress, which then would lead to a reduction in distress in the subsequent week. ClinicalTrials.gov NCT00885014 . April 20, 2009.

  2. Are "part-time" general practitioners workforce idlers or committed professionals?

    PubMed

    Dwan, Kathryn M; Douglas, Kirsty A; Forrest, Laura E

    2014-09-19

    The traditional view of general practice holds that only general practitioners (GPs) in full-time clinical practice can provide quality patient care. Nevertheless, increasing numbers of GPs are choosing to work sessionally, that is, ostensibly "part-time". There are concerns about the health workforce's ability to meet demand and also fears that patient care may be compromised. We sought answers to a) what activities do GPs undertake when not consulting patients, b) why do they choose to work sessionally, and c) does sessional general practice reflect a lack of commitment to patients and the profession? Semi-structured interviews were conducted with GPs who worked sessionally, (i.e. six or fewer sessions a week in clinical general practice, where a session comprises four consecutive hours of patient care). These data were analysed qualitatively and saturation was reached. The majority of participants were in full-time paid employment, while part-time in clinical general practice. They reported that consultations increasingly required the management of patients with complex, chronic conditions who also required psychological management. Coupled with unrealistic patient expectations, these factors led GPs to be concerned about maintaining the quality patient care they considered professionally desirable. Many diversified their work activities to ensure that they retained their professional standards. "Part-time" general practice is a misnomer that masks the contribution these GPs make as part of the health workforce. Sessional practice more accurately describes the nature of our participants' clinical work. Their choice of sessional work is a professional response to the increasing demands within the consultation. It enables GPs to maintain their commitment to quality patient care and their profession, while attenuating the challenges of demanding consultations. Sessional general practitioners demonstrate strong commitment to their patients and the profession.

  3. Lessons learned from the 2011 debacle of the Fukushima nuclear power plant.

    PubMed

    Sugiman, Toshio

    2014-04-01

    The history of nuclear power generation in Japan is analyzed with respect to how the organizational structure of the "nuclear villages," composed of government, private companies and the academic world, negotiated with the growing technology before the Fukushima accident took place. Although nuclear specialists were aware of the potential for a disaster, that did not prevent the enthusiasm for nuclear. The majority of people trusted that new technology would make life easier. The organizational structure of the village consisted of a triangle in which each of the three groups and sub-groups maintained relationships with each other and with the village as a whole to secure its own share of the economic benefits. Based on the sociological theory of norm, we demonstrate that the structure and nature of the relationships in the village facilitated the acceptance of nuclear power despite the element of threat.

  4. Overview of Nuclear Physics Data: Databases, Web Applications and Teaching Tools

    NASA Astrophysics Data System (ADS)

    McCutchan, Elizabeth

    2017-01-01

    The mission of the United States Nuclear Data Program (USNDP) is to provide current, accurate, and authoritative data for use in pure and applied areas of nuclear science and engineering. This is accomplished by compiling, evaluating, and disseminating extensive datasets. Our main products include the Evaluated Nuclear Structure File (ENSDF) containing information on nuclear structure and decay properties and the Evaluated Nuclear Data File (ENDF) containing information on neutron-induced reactions. The National Nuclear Data Center (NNDC), through the website www.nndc.bnl.gov, provides web-based retrieval systems for these and many other databases. In addition, the NNDC hosts several on-line physics tools, useful for calculating various quantities relating to basic nuclear physics. In this talk, I will first introduce the quantities which are evaluated and recommended in our databases. I will then outline the searching capabilities which allow one to quickly and efficiently retrieve data. Finally, I will demonstrate how the database searches and web applications can provide effective teaching tools concerning the structure of nuclei and how they interact. Work supported by the Office of Nuclear Physics, Office of Science of the U.S. Department of Energy under Contract No. DE-AC02-98CH10886.

  5. Nuclear Structure of 186Re

    DTIC Science & Technology

    2016-12-24

    D population-depopulation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 101 AME Atomic Mass Evaluation...this mass region are important for validating models of nuclear structure and reactions. The ENSDF feeds a specific data library relevant to nuclear...spherically asymmetric. Spherical asymmetry is common for nuclei between shell closures, such as those in the mid-shell 150  A  190 mass range of interest

  6. Chromatin insulator bodies are nuclear structures that form in response to osmotic stress and cell death

    PubMed Central

    Schoborg, Todd; Rickels, Ryan; Barrios, Josh

    2013-01-01

    Chromatin insulators assist in the formation of higher-order chromatin structures by mediating long-range contacts between distant genomic sites. It has been suggested that insulators accomplish this task by forming dense nuclear foci termed insulator bodies that result from the coalescence of multiple protein-bound insulators. However, these structures remain poorly understood, particularly the mechanisms triggering body formation and their role in nuclear function. In this paper, we show that insulator proteins undergo a dramatic and dynamic spatial reorganization into insulator bodies during osmostress and cell death in a high osmolarity glycerol–p38 mitogen-activated protein kinase–independent manner, leading to a large reduction in DNA-bound insulator proteins that rapidly repopulate chromatin as the bodies disassemble upon return to isotonicity. These bodies occupy distinct nuclear territories and contain a defined structural arrangement of insulator proteins. Our findings suggest insulator bodies are novel nuclear stress foci that can be used as a proxy to monitor the chromatin-bound state of insulator proteins and provide new insights into the effects of osmostress on nuclear and genome organization. PMID:23878275

  7. Hard QCD processes in the nuclear medium

    NASA Astrophysics Data System (ADS)

    Freese, Adam

    The environment inside the atomic nucleus is one of the most fascinating arenas for the study of quantum chromodynamics (QCD). The strongly-interacting nature of the nuclear medium a?ects the nature of both QCD processes and the quark-gluon structure of hadrons, allowing several unique aspects of the strong nuclear force to be investigated in reactions involving nuclear targets. The research presented in this dissertation explores two aspects of nuclear QCD: firstly, the partonic structure of the nucleus itself; and secondly, the use of the nucleus as a micro-laboratory in which QCD processes can be studied. The partonic structure of the nucleus is calculated in this work by deriving and utilizing a convolution formula. The hadronic structure of the nucleus and the quark-gluon structure of its constituent nucleons are taken together to determine the nuclear partonic structure. Light cone descriptions of short range correlations, in terms of both hadronic and partonic structure, are derived and taken into account. Medium modifications of the bound nucleons are accounted for using the color screening model, and QCD evolution is used to connect nuclear partonic structure at vastly di?erent energy scales. The formalism developed for calculating nuclear partonic structure is applied to inclusive dijet production from proton-nucleus collisions at LHC kinematics, and novel predictions are calculated and presented for the dijet cross section. The nucleus is investigated as a micro-laboratory in vector meson photoproduction reactions. In particular, the deuteron is studied in the break-up reaction gammad → Vpn, for both the φ(1020) and J/v vector mesons. The generalized eikonal approximation is utilized, allowing unambiguous separation of the impulse approximation and final state interactions (FSIs). Two peaks or valleys are seen in the angular distribution of the reaction cross section, each of which is due to an FSI between either the proton and neutron, or the produced vector meson and the spectator nucleon. The presence and size of the latter FSI valley/peak contains information about the meson-nucleon interaction, and it is shown that several models of this interaction can be distinguished by measuring the angular distribution for the deuteron breakup reaction.

  8. Classic Nuclear Localization Signals and a Novel Nuclear Localization Motif Are Required for Nuclear Transport of Porcine Parvovirus Capsid Proteins

    PubMed Central

    Boisvert, Maude; Bouchard-Lévesque, Véronique; Fernandes, Sandra

    2014-01-01

    ABSTRACT Nuclear targeting of capsid proteins (VPs) is important for genome delivery and precedes assembly in the replication cycle of porcine parvovirus (PPV). Clusters of basic amino acids, corresponding to potential nuclear localization signals (NLS), were found only in the unique region of VP1 (VP1up, for VP1 unique part). Of the five identified basic regions (BR), three were important for nuclear localization of VP1up: BR1 was a classic Pat7 NLS, and the combination of BR4 and BR5 was a classic bipartite NLS. These NLS were essential for viral replication. VP2, the major capsid protein, lacked these NLS and contained no region with more than two basic amino acids in proximity. However, three regions of basic clusters were identified in the folded protein, assembled into a trimeric structure. Mutagenesis experiments showed that only one of these three regions was involved in VP2 transport to the nucleus. This structural NLS, termed the nuclear localization motif (NLM), is located inside the assembled capsid and thus can be used to transport trimers to the nucleus in late steps of infection but not for virions in initial infection steps. The two NLS of VP1up are located in the N-terminal part of the protein, externalized from the capsid during endosomal transit, exposing them for nuclear targeting during early steps of infection. Globally, the determinants of nuclear transport of structural proteins of PPV were different from those of closely related parvoviruses. IMPORTANCE Most DNA viruses use the nucleus for their replication cycle. Thus, structural proteins need to be targeted to this cellular compartment at two distinct steps of the infection: in early steps to deliver viral genomes to the nucleus and in late steps to assemble new viruses. Nuclear targeting of proteins depends on the recognition of a stretch of basic amino acids by cellular transport proteins. This study reports the identification of two classic nuclear localization signals in the minor capsid protein (VP1) of porcine parvovirus. The major protein (VP2) nuclear localization was shown to depend on a complex structural motif. This motif can be used as a strategy by the virus to avoid transport of incorrectly folded proteins and to selectively import assembled trimers into the nucleus. Structural nuclear localization motifs can also be important for nuclear proteins without a classic basic amino acid stretch, including multimeric cellular proteins. PMID:25078698

  9. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Hazen Ed., T.C.

    On behalf of the Subsurface Biogeochemical Research (SBR) program managers in the Climate and Environmental Sciences Division (CESD), Office of Biological and Environmental Research (BER), welcome to the 2011 SBR Principal Investigators meeting. Thank you in advance for your attendance and your presentations at this year's meeting. As the events in Japan continue to unfold, we are all reminded that the research we perform on radionuclide behavior in the environment has implications beyond legacy waste cleanup and in fact has its place in the discussion on the expanded use of nuclear power. As in the past, there are three broadmore » objectives to the Principal Investigators meeting: (1) to provide opportunities to share research results and promote interactions among the SBR scientists and other invited guests; (2) to evaluate the progress of each project within the program; and (3) to showcase the scientific expertise and research progress over the past year to senior managers within the DOE Office of Science, the technology offices within DOE, and other invited attendees from other Federal Agencies. This past year has seen a few significant changes within BER and within the SBR program. In November, our Associate Director for BER, Anna Palmisano, retired from Federal service. Just this month, Dr. Sharlene Weatherwax (Division Director for Biological Systems Sciences) has been named as the new Associate Director for BER. In August, BER welcomed Dr. Gary Geernaert as the new Division Director for CESD. Gary joins the division from Los Alamos National Laboratory with a background in atmospheric science. Within the SBR program, a new Strategic Plan was completed last June (currently posted on the SBR and the Office of Science website). The new strategic plan is intended to foster integration within the Environmental Systems Science portion of the BER budget that includes both SBR and Terrestrial Ecosystem Sciences (TES). Both these programs share a goal of advancing a predictive understanding of environmental processes and utilizing iterative, multidisciplinary approaches to understand complex environmental systems of relevance to DOE. CESD in general is undergoing continued discussions on integration among its programs in an effort to develop a new strategic plan for the division. This effort also includes identifying opportunities for integration with BER's Biological Systems Science Division (BSSD). The program this year includes three poster presentation sessions, six plenary sessions, and three breakout sessions. The plenary session on Tuesday morning will feature introductory presentations by BER program staff and three keynote addresses from Dr. Ken Bencala (USGS), Dr. Michael (Mick) Follows (MIT) and Dr. Sue Brantley (PSU) that will lead into three breakout sessions Tuesday afternoon. The breakout sessions are intended to highlight key developments in SBR research and foster a dialog among session participants on scientific paths forward in each particular area. The SBR program managers are asking for input from the SBR community at these sessions to help guide future efforts and/or identify areas of integration within BER programs. On Wednesday, plenary sessions will continue in the morning, followed by an early afternoon poster session. After an extended break for lunch, plenary sessions will continue in the afternoon, followed by an evening poster session. Thursday's plenary session will focus on selected highlights of research efforts at the IFRC sites and on a new potential TES field effort in the Arctic. This new field site is an obvious point of integration between the SBR and TES programs.« less

  10. The nonchromatin substructures of the nucleus: the ribonucleoprotein (RNP)-containing and RNP-depleted matrices analyzed by sequential fractionation and resinless section electron microscopy

    PubMed Central

    1986-01-01

    The nonchromatin structure or matrix of the nucleus has been studied using an improved fractionation in concert with resinless section electron microscopy. The resinless sections show the nucleus of the intact cell to be filled with a dense network or lattice composed of soluble proteins and chromatin in addition to the structural nuclear constituents. In the first fractionation step, soluble proteins are removed by extraction with Triton X-100, and the dense nuclear lattice largely disappears. Chromatin and nonchromatin nuclear fibers are now sharply imaged. Nuclear constituents are further separated into three well-defined, distinct protein fractions. Chromatin proteins are those that require intact DNA for their association with the nucleus and are released by 0.25 M ammonium sulfate after internucleosomal DNA is cut with DNAase I. The resulting structure retains most heterogeneous nuclear ribonucleoprotein (hnRNP) and is designated the RNP-containing nuclear matrix. The proteins of hnRNP are those associated with the nucleus only if RNA is intact. These are released when nuclear RNA is briefly digested with RNAase A. Ribonuclease digestion releases 97% of the hnRNA and its associated proteins. These proteins correspond to the hnRNP described by Pederson (Pederson, T., 1974, J. Mol. Biol., 83:163- 184) and are distinct from the proteins that remain in the ribonucleoprotein (RNP)-depleted nuclear matrix. The RNP-depleted nuclear matrix is a core structure that retains lamins A and C, the intermediate filaments, and a unique set of nuclear matrix proteins (Fey, E. G., K. M. Wan, and S. Penman, 1984, J. Cell Biol. 98:1973- 1984). This core had been previously designated the nuclear matrix- intermediate filament scaffold and its proteins are a third, distinct, and nonoverlapping subset of the nuclear nonhistone proteins. Visualizing the nuclear matrix using resinless sections shows that nuclear RNA plays an important role in matrix organization. Conventional Epon-embedded electron microscopy sections show comparatively little of the RNP-containing and RNP-depleted nuclear matrix structure. In contrast, resinless sections show matrix interior to be a three-dimensional network of thick filaments bounded by the nuclear lamina. The filaments are covered with 20-30-nm electron dense particles which may contain the hnRNA. The large electron dense bodies, enmeshed in the interior matrix fibers, have the characteristic morphology of nucleoli. Treatment of the nuclear matrix with RNAase results in the aggregation of the interior fibers and the extensive loss of the 20-30-nm particles.(ABSTRACT TRUNCATED AT 400 WORDS) PMID:3700470

  11. A Highly Organized Structure Mediating Nuclear Localization of a Myb2 Transcription Factor in the Protozoan Parasite Trichomonas vaginalis ▿ †

    PubMed Central

    Chu, Chien-Hsin; Chang, Lung-Chun; Hsu, Hong-Ming; Wei, Shu-Yi; Liu, Hsing-Wei; Lee, Yu; Kuo, Chung-Chi; Indra, Dharmu; Chen, Chinpan; Ong, Shiou-Jeng; Tai, Jung-Hsiang

    2011-01-01

    Nuclear proteins usually contain specific peptide sequences, referred to as nuclear localization signals (NLSs), for nuclear import. These signals remain unexplored in the protozoan pathogen, Trichomonas vaginalis. The nuclear import of a Myb2 transcription factor was studied here using immunodetection of a hemagglutinin-tagged Myb2 overexpressed in the parasite. The tagged Myb2 was localized to the nucleus as punctate signals. With mutations of its polybasic sequences, 48KKQK51 and 61KR62, Myb2 was localized to the nucleus, but the signal was diffusive. When fused to a C-terminal non-nuclear protein, the Myb2 sequence spanning amino acid (aa) residues 48 to 143, which is embedded within the R2R3 DNA-binding domain (aa 40 to 156), was essential and sufficient for efficient nuclear import of a bacterial tetracycline repressor (TetR), and yet the transport efficiency was reduced with an additional fusion of a firefly luciferase to TetR, while classical NLSs from the simian virus 40 T-antigen had no function in this assay system. Myb2 nuclear import and DNA-binding activity were substantially perturbed with mutation of a conserved isoleucine (I74) in helix 2 to proline that altered secondary structure and ternary folding of the R2R3 domain. Disruption of DNA-binding activity alone by point mutation of a lysine residue, K51, preceding the structural domain had little effect on Myb2 nuclear localization, suggesting that nuclear translocation of Myb2, which requires an ordered structural domain, is independent of its DNA binding activity. These findings provide useful information for testing whether myriad Mybs in the parasite use a common module to regulate nuclear import. PMID:22021237

  12. Live CLEM imaging to analyze nuclear structures at high resolution.

    PubMed

    Haraguchi, Tokuko; Osakada, Hiroko; Koujin, Takako

    2015-01-01

    Fluorescence microscopy (FM) and electron microscopy (EM) are powerful tools for observing molecular components in cells. FM can provide temporal information about cellular proteins and structures in living cells. EM provides nanometer resolution images of cellular structures in fixed cells. We have combined FM and EM to develop a new method of correlative light and electron microscopy (CLEM), called "Live CLEM." In this method, the dynamic behavior of specific molecules of interest is first observed in living cells using fluorescence microscopy (FM) and then cellular structures in the same cell are observed using electron microscopy (EM). Following image acquisition, FM and EM images are compared to enable the fluorescent images to be correlated with the high-resolution images of cellular structures obtained using EM. As this method enables analysis of dynamic events involving specific molecules of interest in the context of specific cellular structures at high resolution, it is useful for the study of nuclear structures including nuclear bodies. Here we describe Live CLEM that can be applied to the study of nuclear structures in mammalian cells.

  13. THE FINE STRUCTURE OF Streptomyces coelicolor

    PubMed Central

    Hopwood, David A.; Glauert, Audrey M.

    1960-01-01

    Colonies and spore suspensions of Streptomyces coelicolor were fixed for electron microscopy by the method of Kellenberger, Ryter, and Séchaud (1958). In thin sections the nuclear regions have a lower average density than the cytoplasm and the outlines of these regions correspond well with the profiles of the chromatinic bodies observed with the light microscope. The nuclear regions contain fibrils, about 5 mµ in diameter. In contrast, after fixation by the method of Palade (1952) the nuclear material is coagulated into irregular dense masses and tubular structures about 20 mµ in diameter, lying in a nuclear "vacuole." The significance of these observations is discussed in relation to the observations of other workers on the fine structure of the nuclear material of other bacteria and the chromosomes of higher cells. PMID:13715794

  14. Structural and functional adaptations of the mammalian nuclear envelope to meet the meiotic requirements.

    PubMed

    Link, Jana; Jahn, Daniel; Alsheimer, Manfred

    2015-01-01

    Numerous studies in the past years provided definite evidence that the nuclear envelope is much more than just a simple barrier. It rather constitutes a multifunctional platform combining structural and dynamic features to fulfill many fundamental functions such as chromatin organization, regulation of transcription, signaling, but also structural duties like maintaining general nuclear architecture and shape. One additional and, without doubt, highly impressive aspect is the recently identified key function of selected nuclear envelope components in driving meiotic chromosome dynamics, which in turn is essential for accurate recombination and segregation of the homologous chromosomes. Here, we summarize the recent work identifying new key players in meiotic telomere attachment and movement and discuss the latest advances in our understanding of the actual function of the meiotic nuclear envelope.

  15. Culturally sensitive patient-centred educational programme for self-management of type 2 diabetes: a randomized controlled trial.

    PubMed

    Mohamed, Hashim; Al-Lenjawi, Badriya; Amuna, Paul; Zotor, Francis; Elmahdi, Hisham

    2013-10-01

    To assess the effectiveness of a culturally sensitive, structured education programme (CSSEP) on biomedical, knowledge, attitude and practice measures among Arabs with type two diabetes. A total of 430 patients with type II diabetes mellitus living in Doha, Qatar were enrolled in the study. They were randomized to either intervention (n = 215) or a control group (n = 215). A baseline and one-year interval levels of biomedical variables including HbA1C, lipid profile, urine for microalbuminuria; in addition to knowledge, attitude and practice (KAP) scores were prospectively measured. The intervention was based on theory of empowerment, health belief models and was culturally sensitive in relation to language (Arabic), food habits and health beliefs. It consisted of four educational sessions for each group of patients (10-20 patients per session), lasting for 3-4 h. The first session discussed diabetes pathophysiology and complications; while the second session discussed healthy life style incorporating the Idaho plate method; and the third session dealt with exercise benefits and goal setting and the fourth session concentrated enhancing attitude and practice using counselling techniques. Outcomes were assessed at base line and 12 months after intervention. After 12 months participation in the intervention was shown to have led to a statistically significant reduction in HbA1C in the (CSSEP) group (-0.55 mmol/L, P = 0.012), fasting blood sugar (-0.92 mmol/L, P = 0.022), body mass index (1.70, P = 0.001) and albumin/creatinine ratio (-3.09, P < 0.0001) but not in the control group. The intervention group also had improvement in Diabetes knowledge (5.9%, P < 0.0001), attitude (6.56%, P < 0.0001), and practice (6.52%, P = 0.0001). This study demonstrates the effectiveness of culturally sensitive, structured, group-based diabetes education in enhancing biomedical and behavioural outcomes in Diabetic patients. Copyright © 2013 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved.

  16. A Short Assessment of Select Remediation Issues at the Russian Research Center-Kurchatov Institute, Moscow, Russia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gephart, Roy E.

    At the invitation of the National Academies, Roy Gephart traveled to Russia with an eight-member U.S. team during June, 2008 to participate in a workshop hosted by the National Academies and the Russian Academy of Sciences on radiation contamination and remediation issues in the former Soviet Union. Cleanup problems were assessed by the American participants for six Russian sites: Kurchatov Institute, Lakes 10 and 11 at Mayak, Andreev Bay, Krasnokamensk Mining Enterprise (Siberia), Almaz Mining Enterprise (North Caucasus), and one site for testing peaceful nuclear explosions. Roy lead the Russian Research Center-Kurchatov Institute review session and wrote an assessment ofmore » key cleanup issues. Kurchatov is the leading institute in the Former Soviet Union devoted to military and civilian nuclear programs. Founded in 1943 in the outskirts of Moscow, this 100 hectare site of nearly undeveloped, prime real estate is now surrounded by densely populated urban and business districts. Today there are growing concerns over the public safety and environmental security of the site resulting from increasingly obsolete nuclear facilities and a legacy of inadequate waste management practices that resulted in contaminant releases and challenging remediation problems. In addition, there is growing concern over the presence of nuclear facilities within urban areas creating potential targets for terrorist attacks.« less

  17. In vitro utilization of ferromagnetic nanoparticles in hemodialysis therapy

    NASA Astrophysics Data System (ADS)

    Stamopoulos, D.; Benaki, D.; Bouziotis, P.; Zirogiannis, P. N.

    2007-12-01

    The in vitro utilization of biocompatible ferromagnetic nanoparticles (BFNs) in hemodialysis (HD), routinely used today for the treatment of end stage renal disease (ESRD), is introduced in this work. The proposed strategy is termed magnetically assisted hemodialysis (MAHD) and it aims to become a more efficient development of conventional HD. The method is based on the production of biocompatible ferromagnetic nanoparticles-targeted binding substances conjugates (BFNs-TBSs Cs) constructed of BFNs and specifically designed TBSs that should have high affinity and binding capacity for target toxic substances (TTSs) which must be removed from the ESRD patient subjected to HD. Antibodies or even specific proteins could serve as the TBS of the desired BFNs-TBSs Cs. The BFNs-TBSs Cs should be administered to the patient timely prior to the MAHD session so as to bind with the desired TTSs during their free circulation in the vascular network. Eventually, the complete BFNs-TBSs-TTSs structure can be selectively removed during the MAHD session by means of an external inhomogeneous magnetic field that is applied either at the dialyzer or at other collection point(s) along the blood circulation line of the dialysis machine. The advantages of MAHD over conventional HD regarding the patient's comfort and overall health status are discussed in detail among practical issues. To examine this proposition we employed Fe3O4 and bovine serum albumin (BSA) as the BFN and the TBS constituents respectively, since they are both highly biocompatible. By means of x-ray diffraction, atomic force microscopy, circular dichroism spectropolarimetry, UV-vis spectrophotometry, SQUID magnetometry, and nuclear magnetic resonance we evaluated (i) the structural/morphological characteristics, (ii) the magnetic retraction efficiency, and most importantly (iii) the toxin binding affinity and capacity of both bare Fe3O4 BFNs and Fe3O4-BSA Cs by performing in vitro experiments on specific TTSs. Homocysteine and p-cresol were chosen as representative TTSs and were investigated in great detail. The results obtained prove the in vitro applicability of the proposed MAHD method.

  18. Nuclear surface diffuseness revealed in nucleon-nucleus diffraction

    NASA Astrophysics Data System (ADS)

    Hatakeyama, S.; Horiuchi, W.; Kohama, A.

    2018-05-01

    The nuclear surface provides useful information on nuclear radius, nuclear structure, as well as properties of nuclear matter. We discuss the relationship between the nuclear surface diffuseness and elastic scattering differential cross section at the first diffraction peak of high-energy nucleon-nucleus scattering as an efficient tool in order to extract the nuclear surface information from limited experimental data involving short-lived unstable nuclei. The high-energy reaction is described by a reliable microscopic reaction theory, the Glauber model. Extending the idea of the black sphere model, we find one-to-one correspondence between the nuclear bulk structure information and proton-nucleus elastic scattering diffraction peak. This implies that we can extract both the nuclear radius and diffuseness simultaneously, using the position of the first diffraction peak and its magnitude of the elastic scattering differential cross section. We confirm the reliability of this approach by using realistic density distributions obtained by a mean-field model.

  19. Innovative Design and Processing of Multi-Functional Adaptive Structural Materials

    DTIC Science & Technology

    2014-01-09

    instability, Journal of the Mechanics and Physics of Solids, (02 2013): 611. doi: 10.1016/j.jmps.2012.09.006 C. Keplinger, J.-Y. Sun , C. C. Foo, P... mechanics meets chemistry.” invited session on De-formation and Fracture of Soft Materials, 2012 March Meeting of the American Physical So-ciety, March... mechanics meets chemistry.” invited session on Deformation and Fracture of Soft Materials, 2012 March Meeting of the American Physi-cal Society

  20. The change in the diffusion of water in normal and degenerative lumbar intervertebral discs following joint mobilization compared to prone lying.

    PubMed

    Beattie, Paul F; Donley, Jonathan W; Arnot, Cathy F; Miller, Ronald

    2009-01-01

    Prospective, repeated measures obtained under treatment and control conditions. The purposes of this study were to provide preliminary evidence regarding the immediate change in the diffusion of water in the nuclear region of normal and degenerative lumbar intervertebral discs (IVDs) following a single session of lumbar joint mobilization, and to compare these findings to the immediate change in the diffusion of water following a 10-minute session of prone lying. There is conflicting evidence regarding the effectiveness and efficacy of lumbar joint mobilization. Increased knowledge of the physiologic effects of lumbar joint mobilization can lead to refinement of its clinical application. A total of 24 people (15 males and 9 females), ranging in age from 22 to 58 years, participated in this study. All subjects had a history of activity-limiting low back pain. Diffusion-weighted magnetic resonance images (DW-MRIs) were obtained immediately before and after a 10-minute session of lumbar joint mobilization. At least 1 month later, a second session was performed in which DW-MRIs were obtained immediately before and after a 10-minute session of prone lying. Following lumbar joint mobilization, a significant increase (P = .002) in the mean values for diffusion of water was observed within degenerative IVDs at L5-S1 (22.2% increase; effect size, 0.97). Degenerative IVDs at L1-2 to L4-5 and normal IVDs at L1-2 to L5-S1 did not demonstrate a change in diffusion following joint mobilization. Prone lying was not associated with a change in diffusion for normal or degenerative IVDs. The stimulus provided by lumbar joint mobilization may influence the diffusion of water in degenerative IVDs at L5-S1; however, these are preliminary findings and the relationship of these findings to pain and function needs further investigation.

  1. 75 FR 34776 - Florida Power & Light Company; Turkey Point Nuclear Generating Plant, Units 3 and 4...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-18

    ... changes to the reactor, fuel, plant, structures, support structures, water, or land at the Turkey Point... NUCLEAR REGULATORY COMMISSION [Docket Nos. 50-250 and 50-251; NRC-2010-0212] Florida Power & Light Company; Turkey Point Nuclear Generating Plant, Units 3 and 4; Environmental Assessment and Finding of No...

  2. Separator assembly for use in spent nuclear fuel shipping cask

    DOEpatents

    Bucholz, James A.

    1983-01-01

    A separator assembly for use in a spent nuclear fuel shipping cask has a honeycomb-type wall structure defining parallel cavities for holding nuclear fuel assemblies. Tubes formed of an effective neutron-absorbing material are embedded in the wall structure around each of the cavities and provide neutron flux traps when filled with water.

  3. 78 FR 15755 - Proposed Revision to Design of Structures, Components, Equipment and Systems; Correction

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-12

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0041] Proposed Revision to Design of Structures, Components, Equipment and Systems; Correction AGENCY: Nuclear Regulatory Commission. ACTION: Standard review... for comments of the proposed revision in Chapter 3, ``Design of Structures, Components, Equipment, and...

  4. 78 FR 19541 - Proposed Revision to Design of Structures, Components, Equipment and Systems

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-01

    ... NUCLEAR REGULATORY COMMISSION [NRC-2013-0041] Proposed Revision to Design of Structures, Components, Equipment and Systems AGENCY: Nuclear Regulatory Commission. ACTION: Standard review plan-draft..., ``Design of Structures, Components, Equipment, and Systems;'' and the request for comment on NUREG-0800...

  5. Neutron scattering for the analysis of biological structures. Brookhaven symposia in biology. Number 27

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Schoenborn, B P

    1976-01-01

    Sessions were included on neutron scattering and biological structure analysis, protein crystallography, neutron scattering from oriented systems, solution scattering, preparation of deuterated specimens, inelastic scattering, data analysis, experimental techniques, and instrumentation. Separate entries were made for the individual papers.

  6. Ethics case reflection sessions: Enablers and barriers.

    PubMed

    Bartholdson, Cecilia; Molewijk, Bert; Lützén, Kim; Blomgren, Klas; Pergert, Pernilla

    2018-03-01

    In previous research on ethics case reflection (ECR) sessions about specific cases, healthcare professionals in childhood cancer care were clarifying their perspectives on the ethical issue to resolve their main concern of consolidating care. When perspectives were clarified, consequences in the team included 'increased understanding', 'group strengthening' and 'decision grounding'. Additional analysis of the data was needed on conditions that could contribute to the quality of ECR sessions. The aim of this study was to explore conditions for clarifying perspectives during ECR sessions. Data were collected from observations and interviews and the results emerged from an inductive analysis using grounded theory. Participants and research context: Six observations during ECR sessions and 10 interviews were performed with healthcare professionals working in childhood cancer care and advanced paediatric homecare. Ethical considerations: The study was approved by a regional ethical review board. Participants were informed about their voluntary involvement and that they could withdraw their participation without explaining why. Two categories emerged: organizational enablers and barriers and team-related enablers and barriers. Organizational enablers and barriers included the following sub-categories: the timing of the ECR session, the structure during the ECR session and the climate during the ECR session. Sub-categories to team-related enablers and barriers were identified as space for inter-professional perspectives, varying levels of ethical skills and space for the patient's and the family's perspectives. Space for inter-professional perspectives included the dominance of a particular perspective that can result from hierarchical positions. The medical perspective is relevant for understanding the child's situation but should not dominate the ethical reflection. Conditions for ECR sessions have been explored and the new knowledge can be used when training facilitators as well as for those who organize/implement ECR sessions. Awareness of space for different perspectives, including the possible medical advantage over the nursing perspective, could reduce the somewhat unilateral attention and contribute to an inter-professionally shared reflection.

  7. Nuclear Quadrupole Moments and Nuclear Shell Structure

    DOE R&D Accomplishments Database

    Townes, C. H.; Foley, H. M.; Low, W.

    1950-06-23

    Describes a simple model, based on nuclear shell considerations, which leads to the proper behavior of known nuclear quadrupole moments, although predictions of the magnitudes of some quadrupole moments are seriously in error.

  8. Teacher Effectiveness Examined as a System: Interpretive Structural Modeling and Facilitation Sessions with U.S. and Japanese Students

    ERIC Educational Resources Information Center

    Georgakopoulos, Alexia

    2009-01-01

    This study challenges narrow definitions of teacher effectiveness and uses a systems approach to investigate teacher effectiveness as a multi-dimensional, holistic phenomenon. The methods of Nominal Group Technique and Interpretive Structural Modeling were used to assist U.S. and Japanese students separately construct influence structures during…

  9. Interdependence of different symmetry energy elements

    NASA Astrophysics Data System (ADS)

    Mondal, C.; Agrawal, B. K.; De, J. N.; Samaddar, S. K.; Centelles, M.; Viñas, X.

    2017-08-01

    Relations between the nuclear symmetry energy coefficient and its density derivatives are derived. The relations hold for a class of interactions with quadratic momentum dependence and a power-law density dependence. The structural connection between the different symmetry energy elements as obtained seems to be followed by almost all reasonable nuclear energy density functionals, both relativistic and nonrelativistic, suggesting a universality in the correlation structure. This, coupled with known values of some well-accepted constants related to nuclear matter, helps in constraining values of different density derivatives of the nuclear symmetry energy, shedding light on the isovector part of the nuclear interaction.

  10. Structural mechanics simulations

    NASA Technical Reports Server (NTRS)

    Biffle, Johnny H.

    1992-01-01

    Sandia National Laboratory has a very broad structural capability. Work has been performed in support of reentry vehicles, nuclear reactor safety, weapons systems and components, nuclear waste transport, strategic petroleum reserve, nuclear waste storage, wind and solar energy, drilling technology, and submarine programs. The analysis environment contains both commercial and internally developed software. Included are mesh generation capabilities, structural simulation codes, and visual codes for examining simulation results. To effectively simulate a wide variety of physical phenomena, a large number of constitutive models have been developed.

  11. Nuclear cartography: patterns in binding energies and subatomic structure

    NASA Astrophysics Data System (ADS)

    Simpson, E. C.; Shelley, M.

    2017-11-01

    Nuclear masses and binding energies are some of the first nuclear properties met in high school physics, and can be used to introduce radioactive decays, fusion, and fission. With relatively little extension, they can also illustrate fundamental concepts in nuclear physics, such as shell structure and pairing, and to discuss how the elements around us were formed in stars. One way of visualising these nuclear properties is through the nuclide chart, which maps all nuclides as a function of their proton and neutron numbers. Here we use the nuclide chart to illustrate various aspects of nuclear physics, and present 3D visualisations of it produced as part of the binding blocks project.

  12. An online database of nuclear electromagnetic moments

    NASA Astrophysics Data System (ADS)

    Mertzimekis, T. J.; Stamou, K.; Psaltis, A.

    2016-01-01

    Measurements of nuclear magnetic dipole and electric quadrupole moments are considered quite important for the understanding of nuclear structure both near and far from the valley of stability. The recent advent of radioactive beams has resulted in a plethora of new, continuously flowing, experimental data on nuclear structure - including nuclear moments - which hinders the information management. A new, dedicated, public and user friendly online database (http://magneticmoments.info) has been created comprising experimental data of nuclear electromagnetic moments. The present database supersedes existing printed compilations, including also non-evaluated series of data and relevant meta-data, while putting strong emphasis on bimonthly updates. The scope, features and extensions of the database are reported.

  13. Statistical Policy for an Aging America. Joint Hearing before the Subcommittee on Energy, Nuclear Proliferation, and Government Processes of the Committee on Governmental Affairs and the Subcommittee on Aging of the Committee on Labor and Human Resources. United States Senate, Ninety-Ninth Congress, Second Session.

    ERIC Educational Resources Information Center

    Congress of the U.S., Washington, DC. Senate Committee on Governmental Affairs.

    Testimony on the need for building an information base on the changing demographics of an aging society in order to make intelligent policy decisions is presented in this Senate committee hearing. Opening statements by Senators Charles Grassley and John Glenn are provided. Jacob A. Brody, dean of the School of Public Health, University of Illinois…

  14. Manualized therapy for PTSD: flexing the structure of cognitive processing therapy.

    PubMed

    Galovski, Tara E; Blain, Leah M; Mott, Juliette M; Elwood, Lisa; Houle, Timothy

    2012-12-01

    This study tested a modified cognitive processing therapy (MCPT) intervention designed as a more flexible administration of the protocol. Number of sessions was determined by client progress toward a priori defined end-state criteria, "stressor sessions" were inserted when necessary, and therapy was conducted by novice CPT clinicians. A randomized, controlled, repeated measures, semicrossover design was utilized (a) to test the relative efficacy of the MCPT intervention compared with a symptom-monitoring delayed treatment (SMDT) condition and (b) to assess within-group variation in change with a sample of 100 male and female interpersonal trauma survivors with posttraumatic stress disorder (PTSD). Hierarchical linear modeling analyses revealed that MCPT evidenced greater improvement on all primary (PTSD and depression) and secondary (guilt, quality of life, general mental health, social functioning, and health perceptions) outcomes compared with SMDT. After the conclusion of SMDT, participants crossed over to MCPT, resulting in a combined MCPT sample (n = 69). Of the 50 participants who completed MCPT, 58% reached end-state criteria prior to the 12th session, 8% at Session 12, and 34% between Sessions 12 and 18. Maintenance of treatment gains was found at the 3-month follow-up, with only 2 of the treated sample meeting criteria for PTSD. Use of stressor sessions did not result in poorer treatment outcomes. Findings suggest that individuals respond at a variable rate to CPT, with significant benefit from additional therapy when indicated and excellent maintenance of gains. Insertion of stressor sessions did not alter the efficacy of the therapy.

  15. The effects of an early intervention music curriculum on prereading/writing.

    PubMed

    Register, D

    2001-01-01

    This study evaluated the effects of music sessions using a curriculum designed to enhance the prereading and writing skills of 25 children aged 4 to 5 years who were enrolled in Early Intervention and Exceptional Student Education programs. This study was a replication of the work of Standley and Hughes (1997) and utilized a larger sample size (n = 50) in order to evaluate the efficacy of a music curriculum designed specifically to teach prereading and writing skills versus one that focuses on all developmental areas. Both the experimental (n = 25) and control (n = 25) groups received two 30-minute sessions each week for an entire school year for a minimum of 60 sessions per group. The differentiating factors between the two groups were the structure and components of the musical activities. The fall sessions for the experimental group were focused primarily on writing skills while the spring sessions taught reading/book concepts. Music sessions for the control group were based purely on the thematic material, as determined by the classroom teacher with purposeful exclusion of all preliteracy concepts. All participants were pretested at the beginning of the school year and posttested before the school year ended. Overall, results demonstrated that music sessions significantly enhanced both groups' abilities to learn prewriting and print concepts. However, the experimental group showed significantly higher results on the logo identification posttest and the word recognition test. Implications for curriculum design and academic and social applications of music in Early Intervention programs are discussed.

  16. Structural Health Monitoring of Nuclear Spent Fuel Storage Facilities

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yu, Lingyu

    Interim storage of spent nuclear fuel from reactor sites has gained additional importance and urgency for resolving waste-management-related technical issues. To ensure that nuclear power remains clean energy, monitoring has been identified by DOE as a high priority cross-cutting need, necessary to determine and predict the degradation state of the systems, structures, and components (SSCs) important to safety (ITS). Therefore, nondestructive structural condition monitoring becomes a need to be installed on existing or to be integrated into future storage system to quantify the state of health or to guarantee the safe operation of nuclear power plants (NPPs) during their extendedmore » life span. In this project, the lead university and the collaborating national laboratory teamed to develop a nuclear structural health monitoring (n-SHM) system based on in-situ piezoelectric sensing technologies that can monitor structural degradation and aging for nuclear spent fuel DCSS and similar structures. We also aimed to identify and quantify possible influences of nuclear spent fuel environment (temperature and radiation) to the piezoelectric sensor system and come up with adequate solutions and guidelines therefore. We have therefore developed analytical model for piezoelectric based n-SHM methods, with considerations of temperature and irradiation influence on the model of sensing and algorithms in acoustic emission (AE), guided ultrasonic waves (GUW), and electromechanical impedance spectroscopy (EMIS). On the other side, experimentally the temperature and irradiation influence on the piezoelectric sensors and sensing capabilities were investigated. Both short-term and long-term irradiation investigation with our collaborating national laboratory were performed. Moreover, we developed multi-modal sensing, validated in laboratory setup, and conducted the testing on the We performed multi-modal sensing development, verification and validation tests on very complex structures including a medium-scale vacuum drying chamber and a small-scale mockup canister available for the desired testing. Our work developed the potential candidate for long term structural health monitoring of spent fuel canister through piezoelectric wafer sensors and provided the sensing methodologies based on AE and GUW methodologies. It overall provides an innovative system and methodology for enhancing the safe operation of nuclear power plant. All major accomplishments planned in the original proposal were successfully achieved.« less

  17. [Drama and forgiveness: the mechanism of action of a new technique in group therapy--face therapy].

    PubMed

    Csigó, Katalin; Bender, Márta; Németh, Attila

    2006-01-01

    In our article we relate our experiences of the face therapy--group therapy sessions held at 2nd Psychiatric Ward of Nyíró Gyula Hospital. Face therapy uses the elements of art therapy and psychodrama: patients form their own head from gypsum and paint it. During the sessions, we analyse the heads and patients reveal their relation to their head. Our paper also presents the structure of thematic sessions and the features of the creative and processing phase. The phenomena that occur during group therapy (self-presentation, self-destruction, creativity) are interpreted with the concepts of psychodynamics and psychodrama. Finally, possible areas of indication are suggested for face therapy and the treatment possibilities for self-destructive phenomena.

  18. Rotating plug bearing and seal

    DOEpatents

    Wade, Elman E.

    1977-01-01

    A bearing and seal structure for nuclear reactors utilizing rotating plugs above the nuclear reactor vessel. The structure permits lubrication of bearings and seals of the rotating plugs without risk of the lubricant draining into the reactor vessel below. The structure permits lubrication by utilizing a rotating outer race bearing.

  19. Half a century of "the nuclear matrix".

    PubMed

    Pederson, T

    2000-03-01

    A cell fraction that would today be termed "the nuclear matrix" was first described and patented in 1948 by Russian investigators. In 1974 this fraction was rediscovered and promoted as a fundamental organizing principle of eukaryotic gene expression. Yet, convincing evidence for this functional role of the nuclear matrix has been elusive and has recently been further challenged. What do we really know about the nonchromatin elements (if any) of internal nuclear structure? Are there objective reasons (as opposed to thinly veiled disdain) to question experiments that use harsh nuclear extraction steps and precipitation-prone conditions? Are the known biophysical properties of the nucleoplasm in vivo consistent with the existence of an extensive network of anastomosing filaments coursing dendritically throughout the interchromatin space? To what extent may the genome itself contribute information for its own quarternary structure in the interphase nucleus? These questions and recent work that bears on the mystique of the nuclear matrix are addressed in this essay. The degree to which gene expression literally depends on nonchromatin nuclear structure as a facilitating organizational format remains an intriguing but unsolved issue in eukaryotic cell biology, and considerable skepticism continues to surround the nuclear matrix fraction as an accurate representation of the in vivo situation.

  20. A study of structure of phenomenology of consciousness in meditative and non-meditative states.

    PubMed

    Venkatesh, S; Raju, T R; Shivani, Y; Tompkins, G; Meti, B L

    1997-04-01

    Twelve senior Kundalini (Chakra) meditators were assessed during meditation session and non-meditation or control session using Phenomenology of Consciousness Inventory. The data has been analyzed using structural analysis to measure the altered state of consciousness and the identity state by comparing meditative state with non-meditative state. The structural analysis of pattern of consciousness during the meditative state revealed altered experience in perception (percentile rank PR = 90), meaning (PR = 82) and time sense (PR = 87), while positive affect dimension showed increased joy (PR = 73) and love (PR = 67). The imagery vividness (PR = 72), self-awareness (PR = 77), rationality (PR = 73) and arousal (PR = 69) were found to be structurally different from the ordinary state. With regards to identity state meditative experience was found to produce statistically significant changes in terms of intensity in meaning (P < 0.05), time sense (P < 0.05), joy (P < 0.05), love (P < 0.05) and state of awareness (P < 0.01). Our results indicate that long term practice of meditation appears to produce structural as well as intensity changes in phenomenological experiences of consciousness.

  1. Nuclear Technology Series. Course 29: Civil/Structural Inspection.

    ERIC Educational Resources Information Center

    Center for Occupational Research and Development, Inc., Waco, TX.

    This technical specialty course is one of thirty-five courses designed for use by two-year postsecondary institutions in five nuclear technician curriculum areas: (1) radiation protection technician, (2) nuclear instrumentation and control technician, (3) nuclear materials processing technician, (4) nuclear quality-assurance/quality-control…

  2. Light Water Reactor Sustainability Program: Survey of Models for Concrete Degradation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Spencer, Benjamin W.; Huang, Hai

    Concrete is widely used in the construction of nuclear facilities because of its structural strength and its ability to shield radiation. The use of concrete in nuclear facilities for containment and shielding of radiation and radioactive materials has made its performance crucial for the safe operation of the facility. As such, when life extension is considered for nuclear power plants, it is critical to have predictive tools to address concerns related to aging processes of concrete structures and the capacity of structures subjected to age-related degradation. The goal of this report is to review and document the main aging mechanismsmore » of concern for concrete structures in nuclear power plants (NPPs) and the models used in simulations of concrete aging and structural response of degraded concrete structures. This is in preparation for future work to develop and apply models for aging processes and response of aged NPP concrete structures in the Grizzly code. To that end, this report also provides recommendations for developing more robust predictive models for aging effects of performance of concrete.« less

  3. Structure of cold nuclear matter at subnuclear densities by quantum molecular dynamics

    NASA Astrophysics Data System (ADS)

    Watanabe, Gentaro; Sato, Katsuhiko; Yasuoka, Kenji; Ebisuzaki, Toshikazu

    2003-09-01

    Structure of cold nuclear matter at subnuclear densities for the proton fraction x=0.5, 0.3, and 0.1 is investigated by quantum molecular dynamics (QMD) simulations. We demonstrate that the phases with slablike and rodlike nuclei, etc. can be formed dynamically from hot uniform nuclear matter without any assumptions on nuclear shape, and also systematically analyze the structure of cold matter using two-point correlation functions and Minkowski functionals. In our simulations, we also observe intermediate phases, which have complicated nuclear shapes. It has been found out that these phases can be characterized as those with negative Euler characteristic. Our result implies the existence of these kinds of phases in addition to the simple “pasta” phases in neutron star crusts and supernova inner cores. In addition, we investigate the properties of the effective QMD interaction used in the present work to examine the validity of our results. The resultant energy per nucleon ɛn of the pure neutron matter, the proton chemical μ(0)p in pure neutron matter and the nuclear surface tension Esurf are generally reasonable in comparison with other nuclear interactions.

  4. Report for 2012 from the Bordeaux IVS Analysis Center

    NASA Technical Reports Server (NTRS)

    Charlot, Patrick; Bellanger, Antoine; Bouffet, Romuald; Bourda, Geraldine; Collioud, Arnaud; Baudry, Alain

    2013-01-01

    This report summarizes the activities of the Bordeaux IVS Analysis Center during the year 2012. The work focused on (i) regular analysis of the IVS-R1 and IVS-R4 sessions with the GINS software package; (ii) systematic VLBI imaging of the RDV sessions and calculation of the corresponding source structure index and compactness values; (iii) investigation of the correlation between astrometric position instabilities and source structure variations; and (iv) continuation of our VLBI observational program to identify optically-bright radio sources suitable for the link with the future Gaia frame. Also of importance is the 11th European VLBI Network Symposium, which we organized last October in Bordeaux and which drew much attention from the European and International VLBI communities.

  5. Theoretical interpretation of the nuclear structure of 88Se within the ACM and the QPM models.

    NASA Astrophysics Data System (ADS)

    Gratchev, I. N.; Thiamova, G.; Alexa, P.; Simpson, G. S.; Ramdhane, M.

    2018-02-01

    The four-parameter algebraic collective model (ACM) Hamiltonian is used to describe the nuclear structure of 88Se. It is shown that the ACM is capable of providing a reasonable description of the excitation energies and relative positions of the ground-state band and γ band. The most probable interpretation of the nuclear structure of 88Se is that of a transitional nucleus. The Quasiparticle-plus-Phonon Model (QPM) was also applied to describe the nuclear motion in 88Se. Preliminarily calculations show that the collectivity of second excited state {2}2+ is weak and that this state contains a strong two-quasiparticle component.

  6. Michigan English Study of Structure for Curriculum Evaluation (MESSAGE).

    ERIC Educational Resources Information Center

    Taylor, Vi Marie

    The Michigan English Study of Structure for Curriculum Evaluation (MESSAGE) training session involved 40 leaders of English curriculum study in a 7-day intensive program. They studied objective evaluation in terms of behavior, instruction, and institution; approaches to the English curriculum through instructional objectives that include…

  7. Impact of Structured Movement Time on Preschoolers' Physical Activity Engagement

    ERIC Educational Resources Information Center

    Palmer, Kara K.; Matsuyama, Abigail L.; Robinson, Leah E.

    2017-01-01

    Preschool-aged children are not meeting national physical activity recommendations. This study compares preschoolers' physical activity engagement during two different physical activity opportunities: outdoor free play or a structured movement session. Eighty-seven children served as participants: 40 children participated in outdoor free play and…

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Benda, Gary; Hayes, David; Gorham, Ron

    The NDA participated in a panel session 31B on Wednesday afternoon starting at 3:15. The NDA is a non-departmental public body, set up in April 2005 under the Energy Act 2004 to take strategic responsibility for the UK's nuclear legacy. Details of their organization and history are located on their web site at www.nda.gov.uk. Also copies of their Power Point presentations made at WM'06 are available on their web site. Their core objective is to ensure that the 20 civil public sector nuclear sites under our ownership are decommissioned and cleaned up safely, securely, cost effectively and in ways thatmore » protect the environment for this and future generations. They lead the development of a unified and coherent decommissioning strategy, working in partnership with regulators and site licensees to achieve best value, optimum impact on local communities, and the highest environmental standards. The NDA's main task is the decommissioning and clean up of civil nuclear sites. If the Government decides it is necessary, however, the Energy Act 2004 allows the NDA to take responsibility for sites currently operated by, or on behalf of, the Ministry of Defence (MoD). Resources will then be transferred from the MoD to meet the costs of clean up. The NDA made a number of presentations to allow conference delegates the opportunity to understand some of the major aspects of their work and to interact with NDA staff. These included the following topics and gave opportunity for audience discussion: - A brief presentation to update on progress by the NDA; - Outline of low level waste management and the prioritisation process; - Discussion of the competition schedule related to low level waste management and the Drigg site. The following presentations and handout were delivered in various sessions of the conference as noted below and are available on their web page including the WM'06 Plenary Session presentation by Sir Anthony Cleaver, Chairman of the NDA. During Session 31B, the following Power Point presentations were made. NDA Overview by David Hayes, Director of Special Projects National M and O Contractor Work Prioritisation Process by Mark Wareing, including topics on: - Need for prioritisation; - Development of the process; - Using the process as a measure of progress. Competition by Ron Gorham, Head of Procurement, including topics on: - The current model; - What NDA are actually competing; - The acquisition process; - NDA aspirations for competition; - NDA aspirations from the market. Low Level Waste Contracting in the UK by Adrian Simper, Expenditure and Programme Strategy Manager, including topics on: - Low Level Waste: NDA responsibilities, Definitions, Arisings; - Proposed NDA Procurement for LLW Management: Scope, Contracting approach, Timetable. The NDA responded to questions from the audience and also announced that the NDA will be holding a special Industry Day for potential contractors interested in the first NDA competition - the Low Level Waste Repository near Drigg in Cumbria. The event is scheduled on the 25-26 April 2006 with more details on their web site at www.nda.gov.uk. (authors)« less

  9. Structure for Storing Properties of Particles (PoP)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Patel, N. R.; Mattoon, C. M.; Beck, B. R.

    2014-06-01

    Some evaluated nuclear databases are critical for applications such as nuclear energy, nuclear medicine, homeland security, and stockpile stewardship. Particle masses, nuclear excitation levels, and other “Properties of Particles” are essential for making evaluated nuclear databases. Currently, these properties are obtained from various databases that are stored in outdated formats. Moreover, the “Properties of Particles” (PoP) structure is being designed that will allow storing all information for one or more particles in a single place, so that each evaluation, simulation, model calculation, etc. can link to the same data. Information provided in PoP will include properties of nuclei, gammas andmore » electrons (along with other particles such as pions, as evaluations extend to higher energies). Presently, PoP includes masses from the Atomic Mass Evaluation version 2003 (AME2003), and level schemes and gamma decays from the Reference Input Parameter Library (RIPL-3). The data are stored in a hierarchical structure. An example of how PoP stores nuclear masses and energy levels will be presented here.« less

  10. On the unification of nuclear-structure theory: A response to Bortignon and Broglia

    NASA Astrophysics Data System (ADS)

    Cook, Norman D.

    2016-09-01

    Nuclear-structure theory is unusual among the diverse fields of quantum physics. Although it provides a coherent description of all known isotopes on the basis of a quantum-mechanical understanding of nucleon states, nevertheless, in the absence of a fundamental theory of the nuclear force acting between nucleons, the prediction of all ground-state and excited-state nuclear binding energies is inherently semi-empirical. I suggest that progress can be made by returning to the foundational work of Eugene Wigner from 1937, where the mathematical symmetries of nucleon states were first defined. Those symmetries were later successfully exploited in the development of the independent-particle model ( IPM ˜ shell model , but the geometrical implications noted by Wigner were neglected. Here I review how the quantum-mechanical, but remarkably easy-to-understand geometrical interpretation of the IPM provides constraints on the parametrization of the nuclear force. The proposed "geometrical IPM" indicates a way forward toward the unification of nuclear-structure theory that Bortignon and Broglia have called for.

  11. Structure for Storing Properties of Particles (PoP)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Patel, N.R., E-mail: infinidhi@llnl.gov; Mattoon, C.M.; Beck, B.R.

    2014-06-15

    Evaluated nuclear databases are critical for applications such as nuclear energy, nuclear medicine, homeland security, and stockpile stewardship. Particle masses, nuclear excitation levels, and other “Properties of Particles” are essential for making evaluated nuclear databases. Currently, these properties are obtained from various databases that are stored in outdated formats. A “Properties of Particles” (PoP) structure is being designed that will allow storing all information for one or more particles in a single place, so that each evaluation, simulation, model calculation, etc. can link to the same data. Information provided in PoP will include properties of nuclei, gammas and electrons (alongmore » with other particles such as pions, as evaluations extend to higher energies). Presently, PoP includes masses from the Atomic Mass Evaluation version 2003 (AME2003), and level schemes and gamma decays from the Reference Input Parameter Library (RIPL-3). The data are stored in a hierarchical structure. An example of how PoP stores nuclear masses and energy levels will be presented here.« less

  12. White Paper on Nuclear Data Needs and Capabilities for Basic Science

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Batchelder, J.; Kawano, T.; Kelley, J.

    Reliable nuclear structure and reaction data represent the fundamental building blocks of nuclear physics and astrophysics research, and are also of importance in many applications. There is a continuous demand for high-quality updates of the main nuclear physics databases via the prompt compilation and evaluation of the latest experimental and theoretical results. The nuclear physics research community benefits greatly from comprehensive, systematic and up-to-date reviews of the experimentally determined nuclear properties and observables, as well as from the ability to rapidly access these data in user-friendly forms. Such credible databases also act as a bridge between science, technology, and societymore » by making the results of basic nuclear physics research available to a broad audience of users, and hence expand the societal utilization of nuclear science. Compilation and evaluation of nuclear data has deep roots in the history of nuclear science research, as outlined in Appendix 1. They have an enormous impact on many areas of science and applications, as illustrated in Figure 2 for the Evaluated Nuclear Structure Data File (ENSDF) database. The present workshop concentrated on the needs of the basic nuclear science community for data and capabilities. The main role of this community is to generate and use data in order to understand the basic nuclear forces and interactions that are responsible for the existence and the properties of all nuclides and, as a consequence, to gain knowledge about the origins, evolution and structure of the universe. Thus, the experiments designed to measure a wealth of nuclear properties towards these fundamental scientific goals are typically performed from within this community.« less

  13. Nucleoporins as components of the nuclear pore complex core structure and Tpr as the architectural element of the nuclear basket.

    PubMed

    Krull, Sandra; Thyberg, Johan; Björkroth, Birgitta; Rackwitz, Hans-Richard; Cordes, Volker C

    2004-09-01

    The vertebrate nuclear pore complex (NPC) is a macromolecular assembly of protein subcomplexes forming a structure of eightfold radial symmetry. The NPC core consists of globular subunits sandwiched between two coaxial ring-like structures of which the ring facing the nuclear interior is capped by a fibrous structure called the nuclear basket. By postembedding immunoelectron microscopy, we have mapped the positions of several human NPC proteins relative to the NPC core and its associated basket, including Nup93, Nup96, Nup98, Nup107, Nup153, Nup205, and the coiled coil-dominated 267-kDa protein Tpr. To further assess their contributions to NPC and basket architecture, the genes encoding Nup93, Nup96, Nup107, and Nup205 were posttranscriptionally silenced by RNA interference (RNAi) in HeLa cells, complementing recent RNAi experiments on Nup153 and Tpr. We show that Nup96 and Nup107 are core elements of the NPC proper that are essential for NPC assembly and docking of Nup153 and Tpr to the NPC. Nup93 and Nup205 are other NPC core elements that are important for long-term maintenance of NPCs but initially dispensable for the anchoring of Nup153 and Tpr. Immunogold-labeling for Nup98 also results in preferential labeling of NPC core regions, whereas Nup153 is shown to bind via its amino-terminal domain to the nuclear coaxial ring linking the NPC core structures and Tpr. The position of Tpr in turn is shown to coincide with that of the nuclear basket, with different Tpr protein domains corresponding to distinct basket segments. We propose a model in which Tpr constitutes the central architectural element that forms the scaffold of the nuclear basket.

  14. Reciprocal Interaction of Dendrite Geometry and Nuclear Calcium-VEGFD Signaling Gates Memory Consolidation and Extinction.

    PubMed

    Hemstedt, Thekla J; Bengtson, C Peter; Ramírez, Omar; Oliveira, Ana M M; Bading, Hilmar

    2017-07-19

    Nuclear calcium is an important signaling end point in synaptic excitation-transcription coupling that is critical for long-term neuroadaptations. Here, we show that nuclear calcium acting via a target gene, VEGFD, is required for hippocampus-dependent fear memory consolidation and extinction in mice. Nuclear calcium-VEGFD signaling upholds the structural integrity and complexity of the dendritic arbor of CA1 neurons that renders those cells permissive for the efficient generation of synaptic input-evoked nuclear calcium transients driving the expression of plasticity-related genes. Therefore, the gating of memory functions rests on the reciprocally reinforcing maintenance of an intact dendrite geometry and a functional synapse-to-nucleus communication axis. In psychiatric and neurodegenerative disorders, therapeutic application of VEGFD may help to stabilize dendritic structures and network connectivity, which may prevent cognitive decline and could boost the efficacy of extinction-based exposure therapies. SIGNIFICANCE STATEMENT This study uncovers a reciprocal relationship between dendrite geometry, the ability to generate nuclear calcium transients in response to synaptic inputs, and the subsequent induction of expression of plasticity-related and dendritic structure-preserving genes. Insufficient nuclear calcium signaling in CA1 hippocampal neurons and, consequently, reduced expression of the nuclear calcium target gene VEGFD, a dendrite maintenance factor, leads to reduced-complexity basal dendrites of CA1 neurons, which severely compromises the animals' consolidation of both memory and extinction memory. The structure-protective function of VEGFD may prove beneficial in psychiatric disorders as well as neurodegenerative and aging-related conditions that are associated with loss of neuronal structures, dysfunctional excitation-transcription coupling, and cognitive decline. Copyright © 2017 the authors 0270-6474/17/376946-10$15.00/0.

  15. Training Select-in Interviewers for Astronaut Selection: A Program Evaluation

    NASA Technical Reports Server (NTRS)

    Hysong, S.; Galarza, L.; Holland, A.; Billica, Roger (Technical Monitor)

    2000-01-01

    Psychological factors critical to the success of short and long-duration missions have been identified in previous research; however, evaluation for such critical factors in astronaut applicants leaves much room for human interpretation. Thus, an evaluator training session was designed to standardize the interpretation of critical factors, as well as the structure of the select-in interview across evaluators. The purpose of this evaluative study was to determine the effectiveness of the evaluator training sessions and their potential impact on evaluator ratings.

  16. Reorganization of the nuclear lamina and cytoskeleton in adipogenesis.

    PubMed

    Verstraeten, Valerie L R M; Renes, Johan; Ramaekers, Frans C S; Kamps, Miriam; Kuijpers, Helma J; Verheyen, Fons; Wabitsch, Martin; Steijlen, Peter M; van Steensel, Maurice A M; Broers, Jos L V

    2011-03-01

    A thorough understanding of fat cell biology is necessary to counter the epidemic of obesity. Although molecular pathways governing adipogenesis are well delineated, the structure of the nuclear lamina and nuclear-cytoskeleton junction in this process are not. The identification of the 'linker of nucleus and cytoskeleton' (LINC) complex made us consider a role for the nuclear lamina in adipose conversion. We herein focused on the structure of the nuclear lamina and its coupling to the vimentin network, which forms a cage-like structure surrounding individual lipid droplets in mature adipocytes. Analysis of a mouse and human model system for fat cell differentiation showed fragmentation of the nuclear lamina and subsequent loss of lamins A, C, B1 and emerin at the nuclear rim, which coincides with reorganization of the nesprin-3/plectin/vimentin complex into a network lining lipid droplets. Upon 18 days of fat cell differentiation, the fraction of adipocytes expressing lamins A, C and B1 at the nuclear rim increased, though overall lamin A/C protein levels were low. Lamin B2 remained at the nuclear rim throughout fat cell differentiation. Light and electron microscopy of a subcutaneous adipose tissue specimen showed striking indentations of the nucleus by lipid droplets, suggestive for an increased plasticity of the nucleus due to profound reorganization of the cellular infrastructure. This dynamic reorganization of the nuclear lamina in adipogenesis is an important finding that may open up new venues for research in and treatment of obesity and nuclear lamina-associated lipodystrophy.

  17. Mechanics of the Nucleus

    PubMed Central

    Lammerding, Jan

    2015-01-01

    The nucleus is the distinguishing feature of eukaryotic cells. Until recently, it was often considered simply as a unique compartment containing the genetic information of the cell and associated machinery, without much attention to its structure and mechanical properties. This article provides compelling examples that illustrate how specific nuclear structures are associated with important cellular functions, and how defects in nuclear mechanics can cause a multitude of human diseases. During differentiation, embryonic stem cells modify their nuclear envelope composition and chromatin structure, resulting in stiffer nuclei that reflect decreased transcriptional plasticity. In contrast, neutrophils have evolved characteristic lobulated nuclei that increase their physical plasticity, enabling passage through narrow tissue spaces in their response to inflammation. Research on diverse cell types further demonstrates how induced nuclear deformations during cellular compression or stretch can modulate cellular function. Pathological examples of disturbed nuclear mechanics include the many diseases caused by mutations in the nuclear envelope proteins lamin A/C and associated proteins, as well as cancer cells that are often characterized by abnormal nuclear morphology. In this article, we will focus on determining the functional relationship between nuclear mechanics and cellular (dys-)function, describing the molecular changes associated with physiological and pathological examples, the resulting defects in nuclear mechanics, and the effects on cellular function. New insights into the close relationship between nuclear mechanics and cellular organization and function will yield a better understanding of normal biology and will offer new clues into therapeutic approaches to the various diseases associated with defective nuclear mechanics. PMID:23737203

  18. Caenorhabditis elegans as a model system for studying the nuclear lamina and laminopathic diseases.

    PubMed

    Bank, Erin M; Gruenbaum, Yosef

    2011-01-01

    The nuclear lamina is a protein-rich network located directly underneath the inner nuclear membrane of metazoan nuclei. The components of the nuclear lamina have been implicated in nearly all nuclear functions; therefore, understanding the structural, mechanical, and signal transducing properties of these proteins is crucial. In addition, mutations in many of these proteins cause a wide range of human diseases, the laminopathies. The structure, function, and interaction of the lamina proteins are conserved among metazoans, emphasizing their fundamental roles in the nucleus. Several of the advances in the field of the nuclear lamina have come from studies performed in Caenorhabditis elegans or on C. elegans proteins expressed in vitro. Here, we discuss the current knowledge about the nuclear lamina, including an overview of the technical tools offered by C. elegans that make it a powerful model organism for the study of the nuclear lamina and laminopathic diseases.

  19. Nuclear Computational Low Energy Initiative (NUCLEI)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Reddy, Sanjay K.

    This is the final report for University of Washington for the NUCLEI SciDAC-3. The NUCLEI -project, as defined by the scope of work, will develop, implement and run codes for large-scale computations of many topics in low-energy nuclear physics. Physics to be studied include the properties of nuclei and nuclear decays, nuclear structure and reactions, and the properties of nuclear matter. The computational techniques to be used include Quantum Monte Carlo, Configuration Interaction, Coupled Cluster, and Density Functional methods. The research program will emphasize areas of high interest to current and possible future DOE nuclear physics facilities, including ATLAS andmore » FRIB (nuclear structure and reactions, and nuclear astrophysics), TJNAF (neutron distributions in nuclei, few body systems, and electroweak processes), NIF (thermonuclear reactions), MAJORANA and FNPB (neutrino-less double-beta decay and physics beyond the Standard Model), and LANSCE (fission studies).« less

  20. Nuclear networking.

    PubMed

    Xie, Wei; Burke, Brian

    2017-07-04

    Nuclear lamins are intermediate filament proteins that represent important structural components of metazoan nuclear envelopes (NEs). By combining proteomics and superresolution microscopy, we recently reported that both A- and B-type nuclear lamins form spatially distinct filament networks at the nuclear periphery of mouse fibroblasts. In particular, A-type lamins exhibit differential association with nuclear pore complexes (NPCs). Our studies reveal that the nuclear lamina network in mammalian somatic cells is less ordered and more complex than that of amphibian oocytes, the only other system in which the lamina has been visualized at high resolution. In addition, the NPC component Tpr likely links NPCs to the A-type lamin network, an association that appears to be regulated by C-terminal modification of various A-type lamin isoforms. Many questions remain, however, concerning the structure and assembly of lamin filaments, as well as with their mode of association with other nuclear components such as peripheral chromatin.

  1. The effect of inflammation and its reduction on brain plasticity in multiple sclerosis: MRI evidence

    PubMed Central

    d'Ambrosio, Alessandro; Petsas, Nikolaos; Wise, Richard G.; Sbardella, Emilia; Allen, Marek; Tona, Francesca; Fanelli, Fulvia; Foster, Catherine; Carnì, Marco; Gallo, Antonio; Pantano, Patrizia; Pozzilli, Carlo

    2016-01-01

    Abstract Brain plasticity is the basis for systems‐level functional reorganization that promotes recovery in multiple sclerosis (MS). As inflammation interferes with plasticity, its pharmacological modulation may restore plasticity by promoting desired patterns of functional reorganization. Here, we tested the hypothesis that brain plasticity probed by a visuomotor adaptation task is impaired with MS inflammation and that pharmacological reduction of inflammation facilitates its restoration. MS patients were assessed twice before (sessions 1 and 2) and once after (session 3) the beginning of Interferon beta (IFN beta), using behavioural and structural MRI measures. During each session, 2 functional MRI runs of a visuomotor task, separated by 25‐minutes of task practice, were performed. Within‐session between‐run change in task‐related functional signal was our imaging marker of plasticity. During session 1, patients were compared with healthy controls. Comparison of patients' sessions 2 and 3 tested the effect of reduced inflammation on our imaging marker of plasticity. The proportion of patients with gadolinium‐enhancing lesions reduced significantly during IFN beta. In session 1, patients demonstrated a greater between‐run difference in functional MRI activity of secondary visual areas and cerebellum than controls. This abnormally large practice‐induced signal change in visual areas, and in functionally connected posterior parietal and motor cortices, was reduced in patients in session 3 compared with 2. Our results suggest that MS inflammation alters short‐term plasticity underlying motor practice. Reduction of inflammation with IFN beta is associated with a restoration of this plasticity, suggesting that modulation of inflammation may enhance recovery‐oriented strategies that rely on patients' brain plasticity. Hum Brain Mapp 37:2431–2445, 2016. © 2016 The Authors Human Brain Mapping Published by Wiley Periodicals, Inc. PMID:26991559

  2. The effect of inflammation and its reduction on brain plasticity in multiple sclerosis: MRI evidence.

    PubMed

    Tomassini, Valentina; d'Ambrosio, Alessandro; Petsas, Nikolaos; Wise, Richard G; Sbardella, Emilia; Allen, Marek; Tona, Francesca; Fanelli, Fulvia; Foster, Catherine; Carnì, Marco; Gallo, Antonio; Pantano, Patrizia; Pozzilli, Carlo

    2016-07-01

    Brain plasticity is the basis for systems-level functional reorganization that promotes recovery in multiple sclerosis (MS). As inflammation interferes with plasticity, its pharmacological modulation may restore plasticity by promoting desired patterns of functional reorganization. Here, we tested the hypothesis that brain plasticity probed by a visuomotor adaptation task is impaired with MS inflammation and that pharmacological reduction of inflammation facilitates its restoration. MS patients were assessed twice before (sessions 1 and 2) and once after (session 3) the beginning of Interferon beta (IFN beta), using behavioural and structural MRI measures. During each session, 2 functional MRI runs of a visuomotor task, separated by 25-minutes of task practice, were performed. Within-session between-run change in task-related functional signal was our imaging marker of plasticity. During session 1, patients were compared with healthy controls. Comparison of patients' sessions 2 and 3 tested the effect of reduced inflammation on our imaging marker of plasticity. The proportion of patients with gadolinium-enhancing lesions reduced significantly during IFN beta. In session 1, patients demonstrated a greater between-run difference in functional MRI activity of secondary visual areas and cerebellum than controls. This abnormally large practice-induced signal change in visual areas, and in functionally connected posterior parietal and motor cortices, was reduced in patients in session 3 compared with 2. Our results suggest that MS inflammation alters short-term plasticity underlying motor practice. Reduction of inflammation with IFN beta is associated with a restoration of this plasticity, suggesting that modulation of inflammation may enhance recovery-oriented strategies that rely on patients' brain plasticity. Hum Brain Mapp 37:2431-2445, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  3. A model teaching session for the hypothesis-driven physical examination.

    PubMed

    Nishigori, Hiroshi; Masuda, Kozo; Kikukawa, Makoto; Kawashima, Atsushi; Yudkowsky, Rachel; Bordage, Georges; Otaki, Junji

    2011-01-01

    The physical examination is an essential clinical competence for all physicians. Most medical schools have students who learn the physical examination maneuvers using a head-to-toe approach. However, this promotes a rote approach to the physical exam, and it is not uncommon for students later on to fail to appreciate the meaning of abnormal findings and their contribution to the diagnostic reasoning process. The purpose of the project was to develop a model teaching session for the hypothesis-driven physical examination (HDPE) approach in which students could practice the physical examination in the context of diagnostic reasoning. We used an action research methodology to create this HDPE model by developing a teaching session, implementing it over 100 times with approximately 700 students, conducting internal reflection and external evaluations, and making adjustments as needed. A model nine-step HDPE teaching session was developed, including: (1) orientation, (2) anticipation, (3) preparation, (4) role play, (5) discussion-1, (6) answers, (7) discussion-2, (8) demonstration and (9) reflection. A structured model HDPE teaching session and tutor guide were developed into a workable instructional intervention. Faculty members are invited to teach the physical examination using this model.

  4. Energy and environmental policy in a period of transition. Proceedings of the twenty-third annual Illinois energy conference

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NONE

    1995-12-31

    The Twenty-Third Annual Illinois Energy Conference entitled, ``Energy and Environmental Policy in a Period of Transition`` was held in Chicago, Illinois on November 20--21, 1995. The conference program explored how federal policy in energy and environment is changing and how these shifts will impact the economy of the Midwest. The conference was divided in four plenary sessions. Session 1 focused on the national policy scene where speakers discussed proposed legislation to change federal energy and environmental policy. Session 2 looked at the future structure of the energy industry, projecting the roles of natural gas, the electric utility industry, and independentmore » power producers in the overall energy system of the 21st century. Session 3 examined current federal policy in research and development as a baseline for discussing the future role of government and industry in supporting research and development. In particular, it looked at the relationship between energy research and development and global competitiveness. Finally, Session 4 attempted to tie these issues together and consider the impact of national policy change on Illinois and the Midwest.« less

  5. Psychodrama: an innovative way of improving self-awareness of nurses.

    PubMed

    Oflaz, F; Meriç, M; Yuksel, Ç; Ozcan, C T

    2011-09-01

    The aim of this educational session was to form a group interaction model for improving the self-awareness of nurses via psychodrama. The structured group interaction session was conducted three times, with three separate groups, during the 'Intensive Care Nursing' training programme at a teaching hospital in Ankara. An assessment was made using the written records and observations of the group director and co-directors and feedback from nurses regarding the session. The nurses were highly motivated, adapting readily to the learning environment and following the instructions without difficulty. They were able to describe their personal experience with a specific patient and also to identify the fundamental emotion engendered by that interaction. Their feedback regarding the session was favourable. The psychodrama technique helped the nurses to understand themselves, to explore the perspective of others and to make the connection between their own thoughts/feelings and those of their patients. Psychodrama can be an effective teaching tool in addressing the communication issues that arise in nursing. © 2011 Blackwell Publishing.

  6. Decline of traditional family system and reproductive behaviour in rural Bangladesh.

    PubMed

    Sarker, P C

    1993-01-01

    This paper is based on data taken from the study entitled Social Structure and Fertility Behavior in a Rural Community of Bangladesh. The field-work was carried out during 1985-86 in Kamnagar, a village in the north-eastern corner of Rajshahi metropolitan city, with a total population of 884. 54.4% of the villagers had no education. Basic information was collected from every household by questionnaires interviewing the head of the household. In the 2nd phase questionnaires were administered to 140 eligible husbands and 140 wives separately to collect information on fertility behavior. 56.8% of the families were nuclear. 12.1% of the families were supplementary nuclear, with parents and their unmarried children including 1 or more additional members. 24.9% of the families were joint, in which related males belonging to 2 or 3 generations lived together with their dependents. 6.2% of the families were extended. As far as the authority structure was concerned, 68.1% of the families were patriarchal, 9.9% of the families were matriarchal, and 22% of the families were egalitarian. The egalitarian authority system is increasing with the spread of female literacy, economic activities outside the home, and women's mobility. Couples in nuclear families are more free to decide on the number of children, birth spacing, and adoption of contraception than those in joint, extended, and supplementary nuclear families with patriarchal and matriarchal authority structures. In nuclear families with an egalitarian authority structure, husband-wife communication can help decide about the number of children wanted, the acceptance of contraceptives, and child spacing. Nuclear families favor lower fertility than supplementary nuclear, joint, and extended families with a patriarchal or matriarchal authority structure. The number of traditional joint and extended families is on the decline with the trend to nuclear families as a result of the increasing landlessness in rural Bangladesh. The authority structure of the family is also changing from patriarchal or matriarchal to egalitarian.

  7. Does the Use of a "Walking Bleaching" Technique Increase Bone Resorption Markers?

    PubMed

    Bersezio, C; Vildósola, P; Sáez, M; Sánchez, F; Vernal, R; Oliveira, O B; Jorquera, G; Basualdo, J; Loguercio, A; Fernández, E

    This randomized clinical trial evaluated the effect of 35% hydrogen peroxide in comparison with 37% carbamide peroxide in a nonvital bleaching technique of "walking bleaching" (four sessions of treatment) on periodontal markers: nuclear factor kappa B-ligand (RANK-L-process of root resorption marker) and interleukin 1β (IL-1β-inflammatory response marker). Fifty volunteers presenting with discoloration of nonvital teeth and endodontic treatment in good condition participated. Fifty teeth were randomly divided into two study groups according to bleaching gel: HP = 35% hydrogen peroxide (n=25) and 37% carbamide peroxide (n=25). Nonvital bleaching was performed with a walking bleaching technique consisting of four sessions of bleach application. Gingival crevicular fluid samples were taken in order to quantify the RANK-L and IL-1β levels by enzyme-linked immunosorbent assay. Samples were obtained from six periodontal sites for each bleached tooth: three vestibular and three palatine (mesial, middle, and distal) at seven time periods: baseline, after each of the four sessions of nonvital bleaching, at one week, and at one month after nonvital bleaching. Tooth color variations were analyzed in each session by VITA Bleachedguide 3D-MASTER (ΔSGU). Significant increments in the RANK-L and IL-1β levels were detected in each evaluated time compared with baseline ( p<0.05); however, no differences were detected between hydrogen peroxide and carbamide peroxide on increments of the biomarkers studied. The change of color was effective for both nonvital bleaching therapies ( p<0.05). Nonvital bleaching induced a significant increment in the RANK-L and IL-1β levels in periodontal tissues around bleached, nonvital teeth.

  8. Undergraduate Course on Global Concerns

    NASA Astrophysics Data System (ADS)

    Richard, G. A.; Weidner, D. J.

    2008-12-01

    GEO 311: Geoscience and Global Concerns is an undergraduate course taught at Stony Brook University during each fall semester. The class meets twice per week, with one session consisting of a lecture and the other, an interactive activity in a computer laboratory that engages the students in exploring real world problems. A specific concern or issue serves as a focus during each session. The students are asked to develop answers to a series of questions that engage them in identifying causes of the problem, connections with the Earth system, relationships to other problems, and possible solutions on both a global and local scale. The questions are designed to facilitate an integrated view of the Earth system. Examples of topics that the students explore during the laboratory sessions are: 1) fossil fuel reserves and consumption rates and the effect of their use on climate, 2) alternative sources of energy and associated technologies, such as solar photovoltaics, nuclear energy, tidal power, geothermal energy, and wind power, 3) effects of tsunamis and earthquakes on human populations and infrastructure, 4) climate change, and 5) hurricanes and storms. The selection and scheduling of topics often takes advantage of the occurrence of media attention or events that can serve as case studies. Tools used during the computer sessions include Google Earth, ArcGIS, spreadsheets, and web sites that offer data and maps. The students use Google Earth or ArcGIS to map events such as earthquakes, storms, tsunamis, and changes in the extent of polar ice. Spreadsheets are employed to discern trends in fossil fuel supply and consumption, and to experiment with models that make predictions for the future. We present examples of several of these activities and discuss how they facilitate an understanding of interrelationships within the Earth system.

  9. Structuring Cooperative Nuclear RIsk Reduction Initiatives with China.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brandt, Larry; Reinhardt, Jason Christian; Hecker, Siegfried

    The Stanford Center for International Security and Cooperation engaged several Chinese nuclear organizations in cooperative research that focused on responses to radiological and nuclear terrorism. The objective was to identify joint research initiatives to reduce the global dangers of such threats and to pursue initial technical collaborations in several high priority areas. Initiatives were identified in three primary research areas: 1) detection and interdiction of smuggled nuclear materials; 2) nuclear forensics; and 3) radiological (“dirty bomb”) threats and countermeasures. Initial work emphasized the application of systems and risk analysis tools, which proved effective in structuring the collaborations. The extensive engagementsmore » between national security nuclear experts in China and the U.S. during the research strengthened professional relationships between these important communities.« less

  10. Transport Properties in Nuclear Pasta

    NASA Astrophysics Data System (ADS)

    Caplan, Matthew; Horowitz, Charles; Berry, Donald; da Silva Schneider, Andre

    2016-09-01

    At the base of the inner crust of neutron stars, where matter is near the nuclear saturation density, nuclear matter arranges itself into exotic shapes such as cylinders and slabs, called `nuclear pasta.' Lepton scattering from these structures may govern the transport properties of the inner crust; electron scattering from protons in the pasta determines the thermal and electrical conductivity, as well as the shear viscosity of the inner crust. These properties may vary in pasta structures which form at various densities, temperatures, and proton fractions. In this talk, we report on our calculations of lepton transport in nuclear pasta and the implication for neutron star observables.

  11. EVALUATED NUCLEAR STRUCTURE DATA FILE AND RELATED PRODUCTS.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    TULI,J.K.

    The Evaluated Nuclear Structure Data File (ENSDF) is a leading resource for the experimental nuclear data. It is maintained and distributed by the National Nuclear Data Center, Brookhaven National Laboratory. The file is mainly contributed to by an international network of evaluators under the auspice of the International Atomic Energy Agency. The ENSDF is updated, generally by mass number, i.e., evaluating together all isobars for a given mass number. If, however, experimental activity in an isobaric chain is limited to a particular nuclide then only that nuclide is updated. The evaluations are published in the journal Nuclear Data Sheets, Academicmore » Press, a division of Elsevier.« less

  12. Physics division annual report 2006.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Glover, J.; Physics

    2008-02-28

    This report highlights the activities of the Physics Division of Argonne National Laboratory in 2006. The Division's programs include the operation as a national user facility of ATLAS, the Argonne Tandem Linear Accelerator System, research in nuclear structure and reactions, nuclear astrophysics, nuclear theory, investigations in medium-energy nuclear physics as well as research and development in accelerator technology. The mission of nuclear physics is to understand the origin, evolution and structure of baryonic matter in the universe--the core of matter, the fuel of stars, and the basic constituent of life itself. The Division's research focuses on innovative new ways tomore » address this mission.« less

  13. An Analysis of Density and Degree-Centrality According to the Social Networking Structure Formed in an Online Learning Environment

    ERIC Educational Resources Information Center

    Ergün, Esin; Usluel, Yasemin Koçak

    2016-01-01

    In this study, we assessed the communication structure in an educational online learning environment using social network analysis (SNA). The communication structure was examined with respect to time, and instructor's participation. The course was implemented using ELGG, a network learning environment, blended with face-to-face sessions over a…

  14. VizieR Online Data Catalog: Brussels nuclear reaction rate library (Aikawa+, 2005)

    NASA Astrophysics Data System (ADS)

    Aikawa, M.; Arnould, M.; Goriely, S.; Jorissen, A.; Takahashi, K.

    2005-07-01

    The present data is part of the Brussels nuclear reaction rate library (BRUSLIB) for astrophysics applications and concerns nuclear reaction rate predictions calculated within the statistical Hauser-Feshbach approximation and making use of global and coherent microscopic nuclear models for the quantities (nuclear masses, nuclear structure properties, nuclear level densities, gamma-ray strength functions, optical potentials) entering the rate calculations. (4 data files).

  15. Nanoscale stiffness topography reveals structure and mechanics of the transport barrier in intact nuclear pore complexes.

    PubMed

    Bestembayeva, Aizhan; Kramer, Armin; Labokha, Aksana A; Osmanović, Dino; Liashkovich, Ivan; Orlova, Elena V; Ford, Ian J; Charras, Guillaume; Fassati, Ariberto; Hoogenboom, Bart W

    2015-01-01

    The nuclear pore complex (NPC) is the gate for transport between the cell nucleus and the cytoplasm. Small molecules cross the NPC by passive diffusion, but molecules larger than ∼5 nm must bind to nuclear transport receptors to overcome a selective barrier within the NPC. Although the structure and shape of the cytoplasmic ring of the NPC are relatively well characterized, the selective barrier is situated deep within the central channel of the NPC and depends critically on unstructured nuclear pore proteins, and is therefore not well understood. Here, we show that stiffness topography with sharp atomic force microscopy tips can generate nanoscale cross-sections of the NPC. The cross-sections reveal two distinct structures, a cytoplasmic ring and a central plug structure, which are consistent with the three-dimensional NPC structure derived from electron microscopy. The central plug persists after reactivation of the transport cycle and resultant cargo release, indicating that the plug is an intrinsic part of the NPC barrier. Added nuclear transport receptors accumulate on the intact transport barrier and lead to a homogenization of the barrier stiffness. The observed nanomechanical properties in the NPC indicate the presence of a cohesive barrier to transport and are quantitatively consistent with the presence of a central condensate of nuclear pore proteins in the NPC channel.

  16. Nanoscale stiffness topography reveals structure and mechanics of the transport barrier in intact nuclear pore complexes

    PubMed Central

    Labokha, Aksana A.; Osmanović, Dino; Liashkovich, Ivan; Orlova, Elena V.; Ford, Ian J.; Charras, Guillaume; Fassati, Ariberto; Hoogenboom, Bart W.

    2014-01-01

    The nuclear pore complex (NPC) is the gate for transport between the cell nucleus and the cytoplasm. Small molecules cross the NPC by passive diffusion, but molecules larger than ~5 nm must bind to nuclear transport receptors to overcome a selective barrier within the NPC1. Whilst the structure and shape of the cytoplasmic ring of the NPC are relatively well characterized2-5, the selective barrier is situated deep within the central channel of the NPC and depends critically on unstructured nuclear pore proteins5,6, and is therefore not well understood. Here, we show that stiffness topography7 with sharp atomic force microscopy tips can generate nanoscale cross sections of the NPC. The cross sections reveal two distinct structures, a cytoplasmic ring and a central plug structure, which are consistent with the three-dimensional NPC structure derived from electron microscopy2-5. The central plug persists after reactivation of the transport cycle and resultant cargo release, indicating that the plug is an intrinsic part of the NPC barrier. Added nuclear transport receptors accumulate on the intact transport barrier and lead to a homogenization of the barrier stiffness. The observed nanomechanical properties in the NPC indicate the presence of a cohesive barrier to transport, and are quantitatively consistent with the presence of a central condensate of nuclear pore proteins in the NPC channel. PMID:25420031

  17. Nanoscale stiffness topography reveals structure and mechanics of the transport barrier in intact nuclear pore complexes

    NASA Astrophysics Data System (ADS)

    Bestembayeva, Aizhan; Kramer, Armin; Labokha, Aksana A.; Osmanović, Dino; Liashkovich, Ivan; Orlova, Elena V.; Ford, Ian J.; Charras, Guillaume; Fassati, Ariberto; Hoogenboom, Bart W.

    2015-01-01

    The nuclear pore complex (NPC) is the gate for transport between the cell nucleus and the cytoplasm. Small molecules cross the NPC by passive diffusion, but molecules larger than ∼5 nm must bind to nuclear transport receptors to overcome a selective barrier within the NPC. Although the structure and shape of the cytoplasmic ring of the NPC are relatively well characterized, the selective barrier is situated deep within the central channel of the NPC and depends critically on unstructured nuclear pore proteins, and is therefore not well understood. Here, we show that stiffness topography with sharp atomic force microscopy tips can generate nanoscale cross-sections of the NPC. The cross-sections reveal two distinct structures, a cytoplasmic ring and a central plug structure, which are consistent with the three-dimensional NPC structure derived from electron microscopy. The central plug persists after reactivation of the transport cycle and resultant cargo release, indicating that the plug is an intrinsic part of the NPC barrier. Added nuclear transport receptors accumulate on the intact transport barrier and lead to a homogenization of the barrier stiffness. The observed nanomechanical properties in the NPC indicate the presence of a cohesive barrier to transport and are quantitatively consistent with the presence of a central condensate of nuclear pore proteins in the NPC channel.

  18. Emerin plays a crucial role in nuclear invagination and in the nuclear calcium transient

    PubMed Central

    Shimojima, Masaya; Yuasa, Shinsuke; Motoda, Chikaaki; Yozu, Gakuto; Nagai, Toshihiro; Ito, Shogo; Lachmann, Mark; Kashimura, Shin; Takei, Makoto; Kusumoto, Dai; Kunitomi, Akira; Hayashiji, Nozomi; Seki, Tomohisa; Tohyama, Shugo; Hashimoto, Hisayuki; Kodaira, Masaki; Egashira, Toru; Hayashi, Kenshi; Nakanishi, Chiaki; Sakata, Kenji; Yamagishi, Masakazu; Fukuda, Keiichi

    2017-01-01

    Alteration of the nuclear Ca2+ transient is an early event in cardiac remodeling. Regulation of the nuclear Ca2+ transient is partly independent of the cytosolic Ca2+ transient in cardiomyocytes. One nuclear membrane protein, emerin, is encoded by EMD, and an EMD mutation causes Emery-Dreifuss muscular dystrophy (EDMD). It remains unclear whether emerin is involved in nuclear Ca2+ homeostasis. The aim of this study is to elucidate the role of emerin in rat cardiomyocytes by means of hypertrophic stimuli and in EDMD induced pluripotent stem (iPS) cell-derived cardiomyocytes in terms of nuclear structure and the Ca2+ transient. The cardiac hypertrophic stimuli increased the nuclear area, decreased nuclear invagination, and increased the half-decay time of the nuclear Ca2+ transient in cardiomyocytes. Emd knockdown cardiomyocytes showed similar properties after hypertrophic stimuli. The EDMD-iPS cell-derived cardiomyocytes showed increased nuclear area, decreased nuclear invagination, and increased half-decay time of the nuclear Ca2+ transient. An autopsied heart from a patient with EDMD also showed increased nuclear area and decreased nuclear invagination. These data suggest that Emerin plays a crucial role in nuclear structure and in the nuclear Ca2+ transient. Thus, emerin and the nuclear Ca2+ transient are possible therapeutic targets in heart failure and EDMD. PMID:28290476

  19. NASA/HAA Advanced Rotorcraft Technology and Tilt Rotor Workshops. Volume 3: Aerodynamics and Structures Session

    NASA Technical Reports Server (NTRS)

    1980-01-01

    Advanced rotorcraft technology and tilt rotor aircraft were discussed. Rotorcraft performance, acoustics, and vibrations were discussed, as was the use of composite materials in rotorcraft structures. Rotorcraft aerodynamics, specifically the aerodynamic phenomena of a rotating and the aerodynamics of fuselages, was discussed.

  20. Mapping the Structure of Semantic Memory

    ERIC Educational Resources Information Center

    Morais, Ana Sofia; Olsson, Henrik; Schooler, Lael J.

    2013-01-01

    Aggregating snippets from the semantic memories of many individuals may not yield a good map of an individual's semantic memory. The authors analyze the structure of semantic networks that they sampled from individuals through a new snowball sampling paradigm during approximately 6 weeks of 1-hr daily sessions. The semantic networks of individuals…

  1. Providing rapid feedback to residents on their teaching skills: an educational strategy for contemporary trainees.

    PubMed

    Katz-Sidlow, Rachel J; Baer, Tamar G; Gershel, Jeffrey C

    2016-03-20

    The objective of this study was to assess the attitudes of contemporary residents toward receiving rapid feedback on their teaching skills from their medical student learners. Participants consisted of 20 residents in their second post-graduate training year. These residents facilitated 44 teaching sessions with medical students within our Resident-as-Teacher program. Structured, written feedback from students was returned to the resident within 3 days following each session. Residents completed a short survey about the utility of the feedback, whether they would make a change to future teaching sessions based on the feedback, and what specifically they might change. The survey utilized a 4-point scale ("Not helpful/likely=1" to "Very helpful/likely=4"), and allowed for one free-text response. Free-text responses were hand-coded and underwent qualitative analysis to identify themes. There were 182 student feedback encounters resulting from 44 teaching sessions. The survey response rate was 73% (32/44). Ninety-four percent of residents rated the rapid feedback as "very helpful," and 91% would "very likely" make a change to subsequent sessions based on student feedback. Residents' proposed changes included modifications to session content and/or their personal teaching style. Residents found that rapid feedback received from medical student learners was highly valuable to them in their roles as teachers. A rapid feedback strategy may facilitate an optimal educational environment for contemporary trainees.

  2. An Unconventional Diacylglycerol Kinase That Regulates Phospholipid Synthesis and Nuclear Membrane Growth*♦

    PubMed Central

    Han, Gil-Soo; O'Hara, Laura; Carman, George M.; Siniossoglou, Symeon

    2008-01-01

    Changes in nuclear size and shape during the cell cycle or during development require coordinated nuclear membrane remodeling, but the underlying molecular events are largely unknown. We have shown previously that the activity of the conserved phosphatidate phosphatase Pah1p/Smp2p regulates nuclear structure in yeast by controlling phospholipid synthesis and membrane biogenesis at the nuclear envelope. Two screens for novel regulators of phosphatidate led to the identification of DGK1. We show that Dgk1p is a unique diacylglycerol kinase that uses CTP, instead of ATP, to generate phosphatidate. DGK1 counteracts the activity of PAH1 at the nuclear envelope by controlling phosphatidate levels. Overexpression of DGK1 causes the appearance of phosphatidate-enriched membranes around the nucleus and leads to its expansion, without proliferating the cortical endoplasmic reticulum membrane. Mutations that decrease phosphatidate levels decrease nuclear membrane growth in pah1Δ cells. We propose that phosphatidate metabolism is a critical factor determining nuclear structure by regulating nuclear membrane biogenesis. PMID:18458075

  3. Nuclear Mechanics in Disease

    PubMed Central

    Zwerger, Monika; Ho, Chin Yee; Lammerding, Jan

    2015-01-01

    Over the past two decades, the biomechanical properties of cells have emerged as key players in a broad range of cellular functions, including migration, proliferation, and differentiation. Although much of the attention has focused on the cytoskeletal networks and the cell’s microenvironment, relatively little is known about the contribution of the cell nucleus. Here, we present an overview of the structural elements that determine the physical properties of the nucleus and discuss how changes in the expression of nuclear components or mutations in nuclear proteins can affect not only nuclear mechanics but also modulate cytoskeletal organization and diverse cellular functions. These findings illustrate that the nucleus is tightly integrated into the surrounding cellular structure. Consequently, changes in nuclear structure and composition are highly relevant to normal development and physiology and can contribute to many human diseases, such as muscular dystrophy, dilated cardiomyopathy, (premature) aging, and cancer. PMID:21756143

  4. Structural integrity of materials in nuclear service: a bibliography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Heddleson, F.A.

    This report contains 679 abstracts from the Nuclear Safety Information Center (NSIC) computer file dated 1973 through 1976 covering material properties with respect to structural integrity. All materials important to the nuclear industry (except concrete) are covered for mechanical properties, chemical properties, corrosion, fracture or failure, radiation damage, creep, cracking, and swelling. Keyword, author, and permuted-title indexes are included for the convenience of the user.

  5. Nuclear magnetic and nuclear quadrupole resonance parameters of β-carboline derivatives calculated using density functional theory

    NASA Astrophysics Data System (ADS)

    Ahmadinejad, Neda; Tari, Mostafa Talebi

    2017-04-01

    A density functional theory (DFT) calculations using B3LYP/6-311++G( d,p) method were carried out to investigate the relative stability of the molecules of β-carboline derivatives such as harmaline, harmine, harmalol, harmane and norharmane. Calculated nuclear quadrupole resonance (NQR) parameters were used to determine the 14N nuclear quadrupole coupling constant χ, asymmetry parameter η and EFG tensor ( q zz ). For better understanding of the electronic structure of β-carboline derivatives, natural bond orbital (NBO) analysis, isotropic and anisotropic NMR chemical shieldings were calculated for 14N nuclei using GIAO method for the optimized structures. The NBO analysis shows that pyrrole ring nitrogen (N9) atom has greater tendency than pyridine ring nitrogen (N2) atom to participate in resonance interactions and aromaticity development in the all of these structures. The NMR and NQR parameters were studied in order to find the correlations between electronic structure and the structural stability of the studied molecules.

  6. Structural Basis for Activation of Fatty Acid-binding Protein 4

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gillilan,R.; Ayers, S.; Noy, N.

    2007-01-01

    Fatty acid-binding protein 4 (FABP4) delivers ligands from the cytosol to the nuclear receptor PPAR{gamma} in the nucleus, thereby enhancing the transcriptional activity of the receptor. Notably, FABP4 binds multiple ligands with a similar affinity but its nuclear translocation is activated only by specific compounds. To gain insight into the structural features that underlie the ligand-specificity in activation of the nuclear import of FABP4, we solved the crystal structures of the protein complexed with two compounds that induce its nuclear translocation, and compared these to the apo-protein and to FABP4 structures bound to non-activating ligands. Examination of these structures indicatesmore » that activation coincides with closure of a portal loop phenylalanine side-chain, contraction of the binding pocket, a subtle shift in a helical domain containing the nuclear localization signal of the protein, and a resultant change in oligomeric state that exposes the nuclear localization signal to the solution. Comparisons of backbone displacements induced by activating ligands with a measure of mobility derived from translation, libration, screw (TLS) refinement, and with a composite of slowest normal modes of the apo state suggest that the helical motion associated with the activation of the protein is part of the repertoire of the equilibrium motions of the apo-protein, i.e. that ligand binding does not induce the activated configuration but serves to stabilize it. Nuclear import of FABP4 can thus be understood in terms of the pre-existing equilibrium hypothesis of ligand binding.« less

  7. From Deuterium to Free Neutrons - Recent Experimental Results

    NASA Astrophysics Data System (ADS)

    Kuhn, Sebastian

    2009-05-01

    Lepton scattering has long been used to gather data on the internal structure of both protons and neutrons. Assuming isospin symmetry, these data can be used to pin down the contributions of both u and d quarks to the spatial and momentum-spin structure of the nucleon and its excitations. In this context, information on the neutron is crucial and is typically obtained from experiments on few-body nuclear targets (predominantly ^3He and deuterium). However, the need to account for binding effects complicates the interpretation of these experiments. On the other hand, detailed studies of the reaction mechanism can yield important new information on the structure of few-body nuclei and the interplay of nuclear and quark degrees of freedom. Recent theoretical and experimental advances have allowed us to make significant progress on both fronts -- a cleaner extraction of neutron properties from nuclear data and a better understanding of nuclear modifications of the bound neutron structure. I will concentrate on recent results on the deuteron. I will present a new extraction of neutron spin structure functions in the resonance and large-x region (from the EG1 experiment with CLAS at Jefferson Lab). The same data can also be used for a detailed comparison with modern calculations of quasi-elastic spin-dependent scattering on the deuteron. A second experimental program with CLAS uses the technique of ``spectator tagging'' to extract the unpolarized structure functions of the neutron with minimal uncertainties from nuclear effects. By mapping out the dependence of the cross section on the ``spectator'' momentum, we can learn about final state interactions between the struck nucleon and the spectator, as well as modifications of the neutron structure due to nuclear binding. I will present preliminary results from the ``BoNuS'' experiment which pushed the detection limit of the spectator proton down to momenta of 70 MeV/c, where nuclear corrections should become small.

  8. 4th International Conference on Energy and Environment 2013 (ICEE 2013)

    NASA Astrophysics Data System (ADS)

    Chakrabarty, Chandan Kumar; Shamsuddin, Abd Halim Bin; Ahmad, Ibrahim Bin; Desa, Mohamed Nor Bin Mohamed; Din, Norashidah Bte Md; Bte Mohd, Lariyah; Hamid, Nasri A.; See, Ong Hang; Hafiz Nagi, Farrukh; Yong, Lee Choon; Pasupuleti, Jagadeesh; Mei, Goh Su; Abdullah, Fairuz Bin; Satgunam, Meenaloshini

    2013-06-01

    The 4th International Conference on Energy & Environment 2013 (ICEE2013) was organized by the Universiti Tenaga Nasional (UNITEN) to provide a platform for creating and sharing ideas among engineers, researchers, scientists, industrialists and students in sustainable green energy and technologies. The theme 'Shaping a Sustainable Future through Advancement in Green Energy Technology' is in line with the University's vision to be a leading global energy university that shapes a sustainable future. The general scopes of the conference are renewable energy, smart grid, green technology, energy policies and economics, sustainable green energy and environment, sustainable education, international cooperation and innovation and technology transfer. Five international keynote speakers delivered their speeches in specialized areas of green energy technology and sustainability. In addition, the conference highlights several special parallel sessions by notable invited presenters in their niche areas, which are: Hybrid Energy Power Quality & Distributed Energy Smart Grid Nuclear Power & Technologies Geohazard Management Greener Environment for Sustainability Advances in Computational Fluid Dynamics The research papers presented in ICEE2013 are included in this volume of IOP Conference Series: Earth and Environmental Science (EES). EES is abstracted and indexed in SCOPUS, GeoBase, GeoRef, Compendex, Inspec, Chemical Abstracts Service, NASA Astrophysics Data System, and International Nuclear Information System (INIS). With the comprehensive programme outline, the organizing committee hopes that the ICEE2013 was a notable intellectual sharing session for the research and academic community in Malaysia and regionally. The organizing committee expresses gratitude to the ICEE2013 delegates for their great support and contributions to the event.

  9. Multidisciplinary Simulation of Graphite-Composite and Cermet Fuel Elements for NTP Point of Departure Designs

    NASA Technical Reports Server (NTRS)

    Stewart, Mark E.; Schnitzler, Bruce G.

    2015-01-01

    This paper compares the expected performance of two Nuclear Thermal Propulsion fuel types. High fidelity, fluid/thermal/structural + neutronic simulations help predict the performance of graphite-composite and cermet fuel types from point of departure engine designs from the Nuclear Thermal Propulsion project. Materials and nuclear reactivity issues are reviewed for each fuel type. Thermal/structural simulations predict thermal stresses in the fuel and thermal expansion mis-match stresses in the coatings. Fluid/thermal/structural/neutronic simulations provide predictions for full fuel elements. Although NTP engines will utilize many existing chemical engine components and technologies, nuclear fuel elements are a less developed engine component and introduce design uncertainty. Consequently, these fuel element simulations provide important insights into NTP engine performance.

  10. Electron-deuteron DIS with spectator tagging at EIC: Development of theoretical framework

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cosyn, Wim B.; Guzey, Vadim A.; Sargsian, Misak M.

    2016-03-01

    An Electron-Ion Collider (EIC) would enable next-generation measurements of deep-inelastic scattering (DIS) on the deuteron with detection of a forward-moving nucleon (p, n) and measurement of its recoil momentum ("spectator tagging''). Such experiments offer full control of the nuclear configuration during the high-energy process and can be used for precision studies of the neutron's partonic structure and its spin dependence, nuclear modifications of partonic structure, and nuclear shadowing at small x. We review the theoretical description of spectator tagging at EIC energies (light-front nuclear structure, on-shell extrapolation in the recoil nucleon momentum, final-state interactions, diffractive effects at small x) andmore » report about on-going developments.« less

  11. Hyperfine structure in 229gTh3+ as a probe of the 229gTh→ 229mTh nuclear excitation energy.

    PubMed

    Beloy, K

    2014-02-14

    We identify a potential means to extract the 229gTh→ 229mTh nuclear excitation energy from precision microwave spectroscopy of the 5F(5/2,7/2) hyperfine manifolds in the ion 229gTh3+. The hyperfine interaction mixes this ground fine structure doublet with states of the nuclear isomer, introducing small but observable shifts to the hyperfine sublevels. We demonstrate how accurate atomic structure calculations may be combined with the measurement of the hyperfine intervals to quantify the effects of this mixing. Further knowledge of the magnetic dipole decay rate of the isomer, as recently reported, allows an indirect determination of the nuclear excitation energy.

  12. The Prolyl Isomerase Pin1 Promotes the Herpesvirus-Induced Phosphorylation-Dependent Disassembly of the Nuclear Lamina Required for Nucleocytoplasmic Egress.

    PubMed

    Milbradt, Jens; Hutterer, Corina; Bahsi, Hanife; Wagner, Sabrina; Sonntag, Eric; Horn, Anselm H C; Kaufer, Benedikt B; Mori, Yasuko; Sticht, Heinrich; Fossen, Torgils; Marschall, Manfred

    2016-08-01

    The nuclear lamina lines the inner nuclear membrane providing a structural framework for the nucleus. Cellular processes, such as nuclear envelope breakdown during mitosis or nuclear export of large ribonucleoprotein complexes, are functionally linked to the disassembly of the nuclear lamina. In general, lamina disassembly is mediated by phosphorylation, but the precise molecular mechanism is still not completely understood. Recently, we suggested a novel mechanism for lamina disassembly during the nuclear egress of herpesviral capsids which involves the cellular isomerase Pin1. In this study, we focused on mechanistic details of herpesviral nuclear replication to demonstrate the general importance of Pin1 for lamina disassembly. In particular, Ser22-specific lamin phosphorylation consistently generates a Pin1-binding motif in cells infected with human and animal alpha-, beta-, and gammaherpesviruses. Using nuclear magnetic resonance spectroscopy, we showed that binding of Pin1 to a synthetic lamin peptide induces its cis/trans isomerization in vitro. A detailed bioinformatic evaluation strongly suggests that this structural conversion induces large-scale secondary structural changes in the lamin N-terminus. Thus, we concluded that a Pin1-induced conformational change of lamins may represent the molecular trigger responsible for lamina disassembly. Consistent with this concept, pharmacological inhibition of Pin1 activity blocked lamina disassembly in herpesvirus-infected fibroblasts and consequently impaired virus replication. In addition, a phospho-mimetic Ser22Glu lamin mutant was still able to form a regular lamina structure and overexpression of a Ser22-phosphorylating kinase did not induce lamina disassembly in Pin1 knockout cells. Intriguingly, this was observed in absence of herpesvirus infection proposing a broader importance of Pin1 for lamina constitution. Thus, our results suggest a functional model of similar events leading to disassembly of the nuclear lamina in response to herpesviral or inherent cellular stimuli. In essence, Pin1 represents a regulatory effector of lamina disassembly that promotes the nuclear pore-independent egress of herpesviral capsids.

  13. The Prolyl Isomerase Pin1 Promotes the Herpesvirus-Induced Phosphorylation-Dependent Disassembly of the Nuclear Lamina Required for Nucleocytoplasmic Egress

    PubMed Central

    Milbradt, Jens; Hutterer, Corina; Bahsi, Hanife; Wagner, Sabrina; Sonntag, Eric; Kaufer, Benedikt B.; Mori, Yasuko; Sticht, Heinrich; Fossen, Torgils; Marschall, Manfred

    2016-01-01

    The nuclear lamina lines the inner nuclear membrane providing a structural framework for the nucleus. Cellular processes, such as nuclear envelope breakdown during mitosis or nuclear export of large ribonucleoprotein complexes, are functionally linked to the disassembly of the nuclear lamina. In general, lamina disassembly is mediated by phosphorylation, but the precise molecular mechanism is still not completely understood. Recently, we suggested a novel mechanism for lamina disassembly during the nuclear egress of herpesviral capsids which involves the cellular isomerase Pin1. In this study, we focused on mechanistic details of herpesviral nuclear replication to demonstrate the general importance of Pin1 for lamina disassembly. In particular, Ser22-specific lamin phosphorylation consistently generates a Pin1-binding motif in cells infected with human and animal alpha-, beta-, and gammaherpesviruses. Using nuclear magnetic resonance spectroscopy, we showed that binding of Pin1 to a synthetic lamin peptide induces its cis/trans isomerization in vitro. A detailed bioinformatic evaluation strongly suggests that this structural conversion induces large-scale secondary structural changes in the lamin N-terminus. Thus, we concluded that a Pin1-induced conformational change of lamins may represent the molecular trigger responsible for lamina disassembly. Consistent with this concept, pharmacological inhibition of Pin1 activity blocked lamina disassembly in herpesvirus-infected fibroblasts and consequently impaired virus replication. In addition, a phospho-mimetic Ser22Glu lamin mutant was still able to form a regular lamina structure and overexpression of a Ser22-phosphorylating kinase did not induce lamina disassembly in Pin1 knockout cells. Intriguingly, this was observed in absence of herpesvirus infection proposing a broader importance of Pin1 for lamina constitution. Thus, our results suggest a functional model of similar events leading to disassembly of the nuclear lamina in response to herpesviral or inherent cellular stimuli. In essence, Pin1 represents a regulatory effector of lamina disassembly that promotes the nuclear pore-independent egress of herpesviral capsids. PMID:27556400

  14. Structural considerations for underground nuclear power plants

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sarne, Y.

    The advantages and disadvantages of underground nuclear power plants are briefly reviewed. The impact of underground contruction on plant layout and structural design are discussed. Schedules and costs for construction are compared with those for conventional plants.

  15. Ultrastructural analysis of v-myb oncogene product cooperation with components of avian cell nuclear matrix.

    PubMed

    Korb, J; Stokrová, J; Karafiát, V

    2000-01-01

    The cooperation of the v-Myb oncoprotein with extracted nuclear matrix of avian haematopoietic cells expressing the v-myb oncogene was studied by means of immunoelectron microscopy. The nuclear matrix was extracted by a gentle method of detergent treatment at moderate ionic strength and visualized either in ultrathin LR White sections, in unembedded resin-free sections, and in addition by the aqueous spreading technique. Using anti-Myb polyclonal antibody we have shown interaction of the v-Myb protein product with extracted nuclear matrix. This oncoprotein, however, was easily released from the structure by a detergent as well as by DNAase treatment and ammonium sulphate extraction. Prefixation of structures before detergent treatment prevented this extraction. The v-Myb protein marker was distributed in clusters or associated with fibrillar structures in most cases. Single markers decorating these fibrillar or less dense structures were also detected.

  16. Basic Nuclear Physics.

    ERIC Educational Resources Information Center

    Bureau of Naval Personnel, Washington, DC.

    Basic concepts of nuclear structures, radiation, nuclear reactions, and health physics are presented in this text, prepared for naval officers. Applications to the area of nuclear power are described in connection with pressurized water reactors, experimental boiling water reactors, homogeneous reactor experiments, and experimental breeder…

  17. The Neural Mechanisms of Re-Experiencing Mental Fatigue Sensation: A Magnetoencephalography Study

    PubMed Central

    Ishii, Akira; Karasuyama, Takuma; Kikuchi, Taiki; Tanaka, Masaaki; Yamano, Emi; Watanabe, Yasuyoshi

    2015-01-01

    There have been several studies which have tried to clarify the neural mechanisms of fatigue sensation; however fatigue sensation has multiple aspects. We hypothesized that past experience related to fatigue sensation is an important factor which contributes to future formation of fatigue sensation through the transfer to memories that are located within specific brain structures. Therefore, we aimed to investigate the neural mechanisms of fatigue sensation related to memory. In the present study, we investigated the neural activity caused by re-experiencing the fatigue sensation that had been experienced during a fatigue-inducing session. Thirteen healthy volunteers participated in fatigue and non-fatigue experiments in a crossover fashion. In the fatigue experiment, they performed a 2-back test session for 40 min to induce fatigue sensation, a rest session for 15 min to recover from fatigue, and a magnetoencephalography (MEG) session in which they were asked to re-experience the state of their body with fatigue that they had experienced in the 2-back test session. In the non-fatigue experiment, the participants performed a free session for 15 min, a rest session for 15 min, and an MEG session in which they were asked to re-experience the state of their body without fatigue that they had experienced in the free session. Spatial filtering analyses of oscillatory brain activity showed that the delta band power in the left Brodmann’s area (BA) 39, alpha band power in the right pulvinar nucleus and the left BA 40, and beta band power in the left BA 40 were lower when they re-experienced the fatigue sensation than when they re-experienced the fatigue-free sensation, indicating that these brain regions are related to re-experiencing the fatigue sensation. Our findings may help clarify the neural mechanisms underlying fatigue sensation. PMID:25826300

  18. TH-E-9A-01: Medical Physics 1.0 to 2.0, Session 4: Computed Tomography, Ultrasound and Nuclear Medicine

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Samei, E; Nelson, J; Hangiandreou, N

    Medical Physics 2.0 is a bold vision for an existential transition of clinical imaging physics in face of the new realities of value-based and evidencebased medicine, comparative effectiveness, and meaningful use. It speaks to how clinical imaging physics can expand beyond traditional insular models of inspection and acceptance testing, oriented toward compliance, towards team-based models of operational engagement, prospective definition and assurance of effective use, and retrospective evaluation of clinical performance. Organized into four sessions of the AAPM, this particular session focuses on three specific modalities as outlined below. CT 2.0: CT has been undergoing a dramatic transition in themore » last few decades. While the changes in the technology merits discussions of their own, an important question is how clinical medical physicists are expected to effectively engage with the new realities of CT technology and practice. Consistent with the upcoming paradigm of Medical Physics 2.0, this CT presentation aims to provide definitions and demonstration of the components of the new clinical medical physics practice pertaining CT. The topics covered include physics metrics and analytics that aim to provide higher order clinicallyrelevant quantification of system performance as pertains to new (and not so new) technologies. That will include the new radiation and dose metrics (SSDE, organ dose, risk indices), image quality metrology (MTF/NPS/d’), task-based phantoms, and the effect of patient size. That will follow with a discussion of the testing implication of new CT hardware (detectors, tubes), acquisition methods (innovative helical geometries, AEC, wide beam CT, dual energy, inverse geometry, application specialties), and image processing and analysis (iterative reconstructions, quantitative CT, advanced renditions). The presentation will conclude with a discussion of clinical and operational aspects of Medical Physics 2.0 including training and communication, use optimization (dose and technique factors), automated analysis and data management (automated QC methods, protocol tracking, dose monitoring, issue tracking), and meaningful QC considerations. US 2.0: Ultrasound imaging is evolving at a rapid pace, adding new imaging functions and modes that continue to enhance its clinical utility and benefits to patients. The ultrasound talk will look ahead 10–15 years and consider how medical physicists can bring maximal value to the clinical ultrasound practices of the future. The roles of physics in accreditation and regulatory compliance, image quality and exam optimization, clinical innovation, and education of staff and trainees will all be considered. A detailed examination of expected technology evolution and impact on image quality metrics will be presented. Clinical implementation of comprehensive physics services will also be discussed. Nuclear Medicine 2.0: Although the basic science of nuclear imaging has remained relatively unchanged since its inception, advances in instrumentation continue to advance the field into new territories. With a great number of these advances occurring over the past decade, the role and testing strategies of clinical nuclear medicine physicists must evolve in parallel. The Nuclear Medicine 2.0 presentation is designed to highlight some of the recent advances from a clinical medical physicist perspective and provide ideas and motivation for designing better evaluation strategies. Topics include improvement of traditional physics metrics and analytics, testing implications of hybrid imaging and advanced detector technologies, and strategies for effective implementation into the clinic. Learning Objectives: Become familiar with new physics metrics and analytics in nuclear medicine, CT, and ultrasound. To become familiar with the major new developments of clinical physics support. To understand the physics testing implications of new technologies, hardware, software, and applications. Identify approaches for implementing comprehensive medical physics services in future imaging practices.« less

  19. Study of Electron Gas on a Neutron-Rich Nuclear Pasta

    NASA Astrophysics Data System (ADS)

    Ramirez-Homs, Enrique

    This study used a classical molecular dynamics model to observe the role of electron gas on the formation of nuclear structures at subsaturation densities (rho < 0.015 fm-3) and low temperatures (T < 1MeV ). The simulations were performed by varying the Coulomb interaction strength on systems of isospin symmetric and asymmetric matter with periodic boundary conditions. The effect was quantified on the fragment size multiplicity, the inter-particle distance, the isospin content of the clusters, the nucleon mobility and cluster persistence, and on the nuclear structure shapes. The existence of the nuclear pasta structures was observed even with the absence of the Coulomb interaction but with a modication of the shapes formed. It was found that the presence of the electron gas tends to distribute matter more evenly, forms less compact objects, decreases the isospin content of clusters, modies the nucleon mobility, reduces the persistence and the fragment size multiplicity, but does not alter the inter-particle distance in clusters. The degree of these effects also varied on the nuclear structures and depended on their isospin content, temperature, and density.

  20. Structural and calorimetric studies demonstrate that the hepatocyte nuclear factor 1β (HNF1β) transcription factor is imported into the nucleus via a monopartite NLS sequence.

    PubMed

    Wiedmann, Mareike M; Aibara, Shintaro; Spring, David R; Stewart, Murray; Brenton, James D

    2016-09-01

    The transcription factor hepatocyte nuclear factor 1β (HNF1β) is ubiquitously overexpressed in ovarian clear cell carcinoma (CCC) and is a potential therapeutic target. To explore potential approaches that block HNF1β transcription we have identified and characterised extensively the nuclear localisation signal (NLS) for HNF1β and its interactions with the nuclear protein import receptor, Importin-α. Pull-down assays demonstrated that the DNA binding domain of HNF1β interacted with a spectrum of Importin-α isoforms and deletion constructs tagged with eGFP confirmed that the HNF1β (229)KKMRRNR(235) sequence was essential for nuclear localisation. We further characterised the interaction between the NLS and Importin-α using complementary biophysical techniques and have determined the 2.4Å resolution crystal structure of the HNF1β NLS peptide bound to Importin-α. The functional, biochemical, and structural characterisation of the nuclear localisation signal present on HNF1β and its interaction with the nuclear import protein Importin-α provide the basis for the development of compounds targeting transcription factor HNF1β via its nuclear import pathway. Copyright © 2016. Published by Elsevier Inc.

  1. Evaluation of a haptics-based virtual reality temporal bone simulator for anatomy and surgery training.

    PubMed

    Fang, Te-Yung; Wang, Pa-Chun; Liu, Chih-Hsien; Su, Mu-Chun; Yeh, Shih-Ching

    2014-02-01

    Virtual reality simulation training may improve knowledge of anatomy and surgical skills. We evaluated a 3-dimensional, haptic, virtual reality temporal bone simulator for dissection training. The subjects were 7 otolaryngology residents (3 training sessions each) and 7 medical students (1 training session each). The virtual reality temporal bone simulation station included a computer with software that was linked to a force-feedback hand stylus, and the system recorded performance and collisions with vital anatomic structures. Subjects performed virtual reality dissections and completed questionnaires after the training sessions. Residents and students had favorable responses to most questions of the technology acceptance model (TAM) questionnaire. The average TAM scores were above neutral for residents and medical students in all domains, and the average TAM score for residents was significantly higher for the usefulness domain and lower for the playful domain than students. The average satisfaction questionnaire for residents showed that residents had greater overall satisfaction with cadaver temporal bone dissection training than training with the virtual reality simulator or plastic temporal bone. For medical students, the average comprehension score was significantly increased from before to after training for all anatomic structures. Medical students had significantly more collisions with the dura than residents. The residents had similar mean performance scores after the first and third training sessions for all dissection procedures. The virtual reality temporal bone simulator provided satisfactory training for otolaryngology residents and medical students. Copyright © 2013. Published by Elsevier Ireland Ltd.

  2. Psychosocial effects of Tai Chi exercise on people with rheumatoid arthritis.

    PubMed

    Waite-Jones, Jennifer M; Hale, Claire A; Lee, Hea-Young

    2013-11-01

    To investigate the perceived psychosocial effects of participating in taught sessions of Tai Chi on people diagnosed with rheumatoid arthritis (RA). Tai Chi is thought to be psychologically as well as physically beneficial for people with arthritis. This study adopted a qualitative approach to follow-up participants who had previously demonstrated physical and psychological benefits from a specifically modified Tai Chi programme in an attempt to explore perceived psychosocial improvements. Nineteen semi-structured, audio-taped, interviews were carried out with participants who had taken part in, twice weekly, group-based Tai Chi sessions for 12 weeks. Data from transcripts were analysed using thematic analysis. Analysis suggests that participating in shared Tai Chi sessions provides increased awareness of the links between mind and body; reduces anxiety and depression; and improves self-esteem, self-efficacy and motivation. It was particularly striking to find that the highly structured nature of Tai Chi was felt to improve memory and seemed to offer aesthetic experiences through developing graceful, 'fluid' moves rather than the 'jarring' movements often imposed by having RA. Such group sessions were found to provide social support and help improve participants' sense of perspective. Although small scale, this study suggests that Tai Chi has the potential to offer psychosocial benefits for people with RA. Offering Tai Chi alongside traditional treatments for RA could promote psychological health and well-being, help inform clinical decision-making and prove cost-effective. © 2013 John Wiley & Sons Ltd.

  3. Co-dependence between trypanosome nuclear lamina components in nuclear stability and control of gene expression.

    PubMed

    Maishman, Luke; Obado, Samson O; Alsford, Sam; Bart, Jean-Mathieu; Chen, Wei-Ming; Ratushny, Alexander V; Navarro, Miguel; Horn, David; Aitchison, John D; Chait, Brian T; Rout, Michael P; Field, Mark C

    2016-12-15

    The nuclear lamina is a filamentous structure subtending the nuclear envelope and required for chromatin organization, transcriptional regulation and maintaining nuclear structure. The trypanosomatid coiled-coil NUP-1 protein is a lamina component functionally analogous to lamins, the major lamina proteins of metazoa. There is little evidence for shared ancestry, suggesting the presence of a distinct lamina system in trypanosomes. To find additional trypanosomatid lamina components we identified NUP-1 interacting proteins by affinity capture and mass-spectrometry. Multiple components of the nuclear pore complex (NPC) and a second coiled-coil protein, which we termed NUP-2, were found. NUP-2 has a punctate distribution at the nuclear periphery throughout the cell cycle and is in close proximity to NUP-1, the NPCs and telomeric chromosomal regions. RNAi-mediated silencing of NUP-2 leads to severe proliferation defects, gross alterations to nuclear structure, chromosomal organization and nuclear envelope architecture. Further, transcription is altered at telomere-proximal variant surface glycoprotein (VSG) expression sites (ESs), suggesting a role in controlling ES expression, although NUP-2 silencing does not increase VSG switching. Transcriptome analysis suggests specific alterations to Pol I-dependent transcription. NUP-1 is mislocalized in NUP-2 knockdown cells and vice versa, implying that NUP-1 and NUP-2 form a co-dependent network and identifying NUP-2 as a second trypanosomatid nuclear lamina component. © The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

  4. Nuclear Scans

    MedlinePlus

    Nuclear scans use radioactive substances to see structures and functions inside your body. They use a special ... images. Most scans take 20 to 45 minutes. Nuclear scans can help doctors diagnose many conditions, including ...

  5. 78 FR 52496 - Sunshine Act Meetings

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-08-23

    ... Executive Session. MATTERS TO BE CONSIDERED: Discuss and select an organization structure for the Foundation..., filing of petitions and applications and agency #0;statements of organization and functions are examples...

  6. The Nuclear Arsenals of the US and USSR.

    ERIC Educational Resources Information Center

    Levi, Barbara G.

    1983-01-01

    Compares United States and Soviet nuclear arsenals, surveying strategic and tactical weapons the two countries have (includes chart detailing strategic nuclear arsenals). Also summarizes trends in nuclear weapons, including use of electronics in surveillance and in command, communication, and control structures. (JN)

  7. NSR&D Program Fiscal Year (FY) 2015 Call for Proposals Mitigation of Seismic Risk at Nuclear Facilities using Seismic Isolation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Coleman, Justin

    2015-02-01

    Seismic isolation (SI) has the potential to drastically reduce seismic response of structures, systems, or components (SSCs) and therefore the risk associated with large seismic events (large seismic event could be defined as the design basis earthquake (DBE) and/or the beyond design basis earthquake (BDBE) depending on the site location). This would correspond to a potential increase in nuclear safety by minimizing the structural response and thus minimizing the risk of material release during large seismic events that have uncertainty associated with their magnitude and frequency. The national consensus standard America Society of Civil Engineers (ASCE) Standard 4, Seismic Analysismore » of Safety Related Nuclear Structures recently incorporated language and commentary for seismically isolating a large light water reactor or similar large nuclear structure. Some potential benefits of SI are: 1) substantially decoupling the SSC from the earthquake hazard thus decreasing risk of material release during large earthquakes, 2) cost savings for the facility and/or equipment, and 3) applicability to both nuclear (current and next generation) and high hazard non-nuclear facilities. Issue: To date no one has evaluated how the benefit of seismic risk reduction reduces cost to construct a nuclear facility. Objective: Use seismic probabilistic risk assessment (SPRA) to evaluate the reduction in seismic risk and estimate potential cost savings of seismic isolation of a generic nuclear facility. This project would leverage ongoing Idaho National Laboratory (INL) activities that are developing advanced (SPRA) methods using Nonlinear Soil-Structure Interaction (NLSSI) analysis. Technical Approach: The proposed study is intended to obtain an estimate on the reduction in seismic risk and construction cost that might be achieved by seismically isolating a nuclear facility. The nuclear facility is a representative pressurized water reactor building nuclear power plant (NPP) structure. Figure 1: Project activities The study will consider a representative NPP reinforced concrete reactor building and representative plant safety system. This study will leverage existing research and development (R&D) activities at INL. Figure 1 shows the proposed study steps with the steps in blue representing activities already funded at INL and the steps in purple the activities that would be funded under this proposal. The following results will be documented: 1) Comparison of seismic risk for the non-seismically isolated (non-SI) and seismically isolated (SI) NPP, and 2) an estimate of construction cost savings when implementing SI at the site of the generic NPP.« less

  8. Nuclear abundance measurements inside MIR and ISS with Sileye experiments

    NASA Astrophysics Data System (ADS)

    Casolino, M.

    In this work we present measurements of cosmic ray nuclear abundances above 150 MeV/n performed inside Mir space station between 1998 and 2000. Data have been obtained with SilEye-2 detector, a 6 plane silicon strip detector telescope designed to measure environmental radiation and investigate on the Light Flash phenomenon. In standalone mode, SilEye-2 is capable to measure LET distribution spectra and identify nuclear species with energy above 100 MeV/n: a total of 100 sessions comprising more than 1000 hours of observation were perfomed in the years 1998-2000, recording also several Solar Energetic Particle (SEP) events. Cosmic ray abundances inside a spacecraft can differ from the primary component due to interaction with the interposed material of the hull and the instruments. We report on LET measurements and relative abundances from Boron to Iron measured in different regions and at different geomagnetic cutoffs, in solar quiet conditions and during SEP events, showing how the composition varies in these different situations. We also report on preliminary results on cosmic ray measurements inside ISS (27/4/2002 - 4/5/2002) obtained with Sileye-3/Alteino experiment.

  9. Quantum Monte Carlo methods for nuclear physics

    DOE PAGES

    Carlson, J.; Gandolfi, S.; Pederiva, F.; ...

    2015-09-09

    Quantum Monte Carlo methods have proved valuable to study the structure and reactions of light nuclei and nucleonic matter starting from realistic nuclear interactions and currents. These ab-initio calculations reproduce many low-lying states, moments, and transitions in light nuclei, and simultaneously predict many properties of light nuclei and neutron matter over a rather wide range of energy and momenta. The nuclear interactions and currents are reviewed along with a description of the continuum quantum Monte Carlo methods used in nuclear physics. These methods are similar to those used in condensed matter and electronic structure but naturally include spin-isospin, tensor, spin-orbit,more » and three-body interactions. A variety of results are presented, including the low-lying spectra of light nuclei, nuclear form factors, and transition matrix elements. Low-energy scattering techniques, studies of the electroweak response of nuclei relevant in electron and neutrino scattering, and the properties of dense nucleonic matter as found in neutron stars are also described. Furthermore, a coherent picture of nuclear structure and dynamics emerges based upon rather simple but realistic interactions and currents.« less

  10. Quantum Monte Carlo methods for nuclear physics

    DOE PAGES

    Carlson, Joseph A.; Gandolfi, Stefano; Pederiva, Francesco; ...

    2014-10-19

    Quantum Monte Carlo methods have proved very valuable to study the structure and reactions of light nuclei and nucleonic matter starting from realistic nuclear interactions and currents. These ab-initio calculations reproduce many low-lying states, moments and transitions in light nuclei, and simultaneously predict many properties of light nuclei and neutron matter over a rather wide range of energy and momenta. We review the nuclear interactions and currents, and describe the continuum Quantum Monte Carlo methods used in nuclear physics. These methods are similar to those used in condensed matter and electronic structure but naturally include spin-isospin, tensor, spin-orbit, and three-bodymore » interactions. We present a variety of results including the low-lying spectra of light nuclei, nuclear form factors, and transition matrix elements. We also describe low-energy scattering techniques, studies of the electroweak response of nuclei relevant in electron and neutrino scattering, and the properties of dense nucleonic matter as found in neutron stars. A coherent picture of nuclear structure and dynamics emerges based upon rather simple but realistic interactions and currents.« less

  11. Thermal-neutron capture gamma-rays. Volume 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tuli, J.K.

    1997-05-01

    The energy and photon intensity of gamma rays as seen in thermal-neutron capture are presented ordered by Z, A of target nuclei. All gamma-rays with intensity of {ge}2% of the strongest transition are included. The strongest transition is indicated in each case. Where the target nuclide mass number is indicated as nat the natural target was used. The gamma energies given are in keV. The gamma intensities given are relative to 100 for the strongest transition. All data for A > 44 are taken from Evaluated Nuclear Structure Data File (4/97), a computer file of evaluated nuclear structure data maintainedmore » by the National Nuclear Data Center, Brookhaven National Laboratory, on behalf of the Nuclear Structure and Decay and Decay Data network, coordinated by the International Atomic Energy Agency, Vienna. These data are published in Nuclear Data Sheets, Academic Press, San Diego, CA. The data for A {le} 44 is taken from ``Prompt Gamma Rays from Thermal-Neutron Capture,`` M.A. Lone, R.A. Leavitt, D.A. Harrison, Atomic Data and Nuclear Data Tables 26, 511 (1981).« less

  12. Thermal-neutron capture gamma-rays. Volume 1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tuli, J.K.

    1997-05-01

    The energy and photon intensity of gamma rays as seen in thermal-neutron capture are presented in ascending order of gamma energy. All those gamma-rays with intensity of {ge} 2% of the strongest transition are included. The two strongest transitions seen for the target nuclide are indicated in each case. Where the target nuclide mass number is indicated as nat the natural target was used. The gamma energies given are in keV. The gamma intensities given are relative to 100 for the strongest transition. All data for A > 44 are taken from Evaluated Nuclear Structure Data File (4/97), a computermore » file of evaluated nuclear structure data maintained by the National Nuclear Data Center, Brookhaven National Laboratory, on behalf of the Nuclear Structure and Decay and Decay Data network, coordinated by the International Atomic Energy Agency, Vienna. These data are published in Nuclear Data Sheets, Academic Press, San Diego, CA. The data for A {le} 44 is taken from ``Prompt Gamma Rays from Thermal-Neutron Capture,`` M.A. Lone, R.A. Leavitt, D.A. Harrison, Atomic Data and Nuclear Data Tables 26, 511 (1981).« less

  13. Foreign and Domestic Policy Belief Structures in the U.S. and British Publics

    ERIC Educational Resources Information Center

    Jenkins-Smith, Hank C.; Mitchell, Neil J.; Herron, Kerry G.

    2004-01-01

    Scholars have made little progress in exploring the degree to which research on belief structures among Americans may be generalizable to other political systems and geopolitical contexts. The distribution and structure of mass beliefs related to nuclear security, missile defenses, and nuclear energy issues in the United States and Great Britain…

  14. How are scientific thinking skills best developed? Direct instruction vs. inquiry practice

    NASA Astrophysics Data System (ADS)

    Dean, David Worth, Jr.

    Despite its support and adoption by most major scientific and educational organizations, some researchers have questioned whether inquiry learning is indeed the best method for acquiring the skills of inquiry. Klahr and colleagues have investigated the development of the control of variables strategy, or controlled comparison (CC), and claim that a brief session of direct instruction, characterized by explicit training of CC, as opposed to allowing children to discover CC through inquiry learning, is sufficient for acquisition, maintenance, and transfer of this core aspect of inquiry. Kuhn and colleagues, however, argue that direct instruction may be insufficient for development of the metastrategic level of understanding necessary to adequately maintain and transfer inquiry skills. In the present study, I attempt to identify the intervention most effective in supporting acquisition, maintenance, and transfer of these skills. Three groups of students received either a direct instruction session followed by standard classroom instruction (DI-only), an introductory session (without direct instruction) followed by practice sessions only (PR-only), or a direct instruction session followed by practice sessions (DI+PR). Practice sessions involved the use of a computer-based inquiry task requiring students to investigate the effects of five potential causal variables on an outcome. The two practice groups worked with this program during 12 sessions over nine weeks. They worked with structurally identical software programs during five weekly maintenance sessions. During this time, the DI-only group received standard classroom instruction. All groups were assessed on familiar and unfamiliar computer-based inquiry tasks at the conclusion of intervention (immediate assessment) and maintenance sessions (delayed assessment). Students in the two practice groups demonstrated improvement in an integrative measure of inquiry skill (valid intent, valid strategy, valid inference, and valid explanation, in combination) as well as most component measures of this skill. Performance of the two practice groups was superior to that of the DI-only group. Direct instruction conferred no additional benefit to the group receiving both direct instruction and practice compared to the practice-only group. Examined over an extended time interval, the merits of brief direct instruction are thus brought into question.

  15. NUCLEAR CHEMISTRY ANNUAL REPORT 1970

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Authors, Various

    Papers are presented for the following topics: (1) Nuclear Structure and Nuclear Properties - (a) Nuclear Spectroscopy and Radioactivity; (b) Nuclear Reactions and Scattering; (c) Nuclear Theory; and (d) Fission. (2) Chemical and Atomic Physics - (a) Atomic and Molecular Spectroscopy; and (b) Hyperfine Interactions. (3) Physical, Inorganic, and Analytical Chemistry - (a) X-Ray Crystallography; (b) Physical and Inorganic Chemistry; (c) Radiation Chemistry; and (d) Chemical Engineering. (4) Instrumentation and Systems Development.

  16. Applying a structured innovation process to interventional radiology: a single-center experience.

    PubMed

    Sista, Akhilesh K; Hwang, Gloria L; Hovsepian, David M; Sze, Daniel Y; Kuo, William T; Kothary, Nishita; Louie, John D; Yamada, Kei; Hong, Richard; Dhanani, Riaz; Brinton, Todd J; Krummel, Thomas M; Makower, Joshua; Yock, Paul G; Hofmann, Lawrence V

    2012-04-01

    To determine the feasibility and efficacy of applying an established innovation process to an active academic interventional radiology (IR) practice. The Stanford Biodesign Medical Technology Innovation Process was used as the innovation template. Over a 4-month period, seven IR faculty and four IR fellow physicians recorded observations. These observations were converted into need statements. One particular need relating to gastrostomy tubes was diligently screened and was the subject of a single formal brainstorming session. Investigators collected 82 observations, 34 by faculty and 48 by fellows. The categories that generated the most observations were enteral feeding (n = 9, 11%), biopsy (n = 8, 10%), chest tubes (n = 6, 7%), chemoembolization and radioembolization (n = 6, 7%), and biliary interventions (n = 5, 6%). The output from the screening on the gastrostomy tube need was a specification sheet that served as a guidance document for the subsequent brainstorming session. The brainstorming session produced 10 concepts under three separate categories. This formalized innovation process generated numerous observations and ultimately 10 concepts to potentially to solve a significant clinical need, suggesting that a structured process can help guide an IR practice interested in medical innovation. Copyright © 2012 SIR. Published by Elsevier Inc. All rights reserved.

  17. The use of virtual patient scenarios as a vehicle for teaching professionalism.

    PubMed

    Marei, H F; Al-Eraky, M M; Almasoud, N N; Donkers, J; Van Merrienboer, J J G

    2018-05-01

    This study aimed to measure students' perceptions of virtual patient scenarios (VPs) for developing ethical reasoning skills and to explore features in VP design that are necessary to promote professionalism. Sixty-five dental students participated in learning sessions that involved collaborative practice with five VPs (four high fidelity and one low fidelity), followed by reflection sessions. Students' perceptions towards the use of VPs in developing ethical reasoning skills were assessed using a questionnaire that involved 10 closed and three open-ended questions. High-fidelity VPs were perceived as significantly better for developing ethical reasoning skills than low-fidelity VPs. Analyses of answers to open-ended questions revealed two new features that are specific for VPs intended for teaching professionalism, which are VP dramatic structure and how it should end. VPs intended for teaching professionalism need to have high fidelity, follow a specific dramatic structure and should include multiple plausible endings. The use of VPs as part of a collaborative activity that is followed by a reflection session is perceived as an effective tool for the development of ethical reasoning skills in dental education. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  18. Fission yeast Lem2 and Man1 perform fundamental functions of the animal cell nuclear lamina.

    PubMed

    Gonzalez, Yanira; Saito, Akira; Sazer, Shelley

    2012-01-01

    In animal cells the nuclear lamina, which consists of lamins and lamin-associated proteins, serves several functions: it provides a structural scaffold for the nuclear envelope and tethers proteins and heterochromatin to the nuclear periphery. In yeast, proteins and large heterochromatic domains including telomeres are also peripherally localized, but there is no evidence that yeast have lamins or a fibrous nuclear envelope scaffold. Nonetheless, we found that the Lem2 and Man1 proteins of the fission yeast Schizosaccharomyces pombe, evolutionarily distant relatives of the Lap2/Emerin/Man1 (LEM) sub-family of animal cell lamin-associated proteins, perform fundamental functions of the animal cell lamina. These integral inner nuclear membrane localized proteins, with nuclear localized DNA binding Helix-Extension-Helix (HEH) domains, impact nuclear envelope structure and integrity, are essential for the enrichment of telomeres at the nuclear periphery and by means of their HEH domains anchor chromatin, most likely transcriptionally repressed heterochromatin, to the nuclear periphery. These data indicate that the core functions of the nuclear lamina are conserved between fungi and animal cells and can be performed in fission yeast, without lamins or other intermediate filament proteins.

  19. NNDC Databases

    Science.gov Websites

    radiation. It includes an interactive chart of nuclides and a level plotting tool. XUNDL Experimental Unevaluated Nuclear Data List Experimental nuclear structure and decay data, covering more than 2,500 recent parameters* Retrieved information CSISRS alias EXFOR Nuclear reaction experimental data Experimental nuclear

  20. Is There a Best Way to Structure the Administration?

    ERIC Educational Resources Information Center

    Kenward, Jack

    2008-01-01

    This article is based on sessions at AUA Conferences in 2006 and 2007, which looked at some factors to take into account when considering the structure of the administration. Roughly, "administration" is defined as the "non-academic" management and operations that support the delivery of teaching and learning, research, and enterprise--in old…

  1. Beyond Labeling: The Role of Maternal Input in the Acquisition of Richly Structured Categories.

    ERIC Educational Resources Information Center

    Gelman, Susan A.; Coley, John D.; Rosengren, Karl S.; Hartman, Erin; Pappas, Athina

    1998-01-01

    Explored how mothers convey information about category structure during naturalistic interactions. Videotaped reading-aloud sessions between mothers and toddlers; coded their interactions for explicit and implicit discussion of animal and artifact categories. Found that mothers provided a rich array of information beyond simple labeling routines,…

  2. Journal Clubs and Case Conferences: From Academic Tradition to Communities of Practice

    ERIC Educational Resources Information Center

    Price, David W.; Felix, Kate G.

    2008-01-01

    Introduction: As small group learning sessions, Journal Clubs (JCs) and Case Conferences (CCs), if structured interactively, have potential as educational formats that can change practice. However, the degree to which these formats, as currently typically structured, lead to practice change is unknown. Methods: We used concepts of communities of…

  3. The Jovian Atmospheres

    NASA Technical Reports Server (NTRS)

    Allison, Michael (Editor); Travis, Larry D. (Editor)

    1986-01-01

    A conference on the atmosphere of Jupiter produced papers in the areas of thermal and ortho-para hydrogen structure, clouds and chemistry, atmospheric structure, global dynamics, synoptic features and processes, atmospheric dynamics, and future spaceflight opportunities. A session on the atmospheres of Uranus and Neptune was included, and the atmosphere of Saturn was discussed in several papers.

  4. Workshop on the interface between radiation chemistry and radiation physics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1983-03-01

    Twenty-four papers are grouped under the session headings: measurements of physical and chemical properties, track structure modeling, spurs and track structure, and the 10/sup -16/ to 10/sup -12/ second region. Separate abstracts were prepared for 12 of the papers; four of the remaining papers had previously been abstracted. (DLC)

  5. Development and Initial Testing of a Structured Clinical Observation Tool to Assess Pharmacotherapy Competence

    ERIC Educational Resources Information Center

    Young, John Q.; Lieu, Sandra; O'Sullivan, Patricia; Tong, Lowell

    2011-01-01

    Objective: The authors developed and tested the feasibility and utility of a new direct-observation instrument to assess trainee performance of a medication management session. Methods: The Psychopharmacotherapy-Structured Clinical Observation (P-SCO) instrument was developed based on multiple sources of expertise and then implemented in 4…

  6. Organizational Structure and Strategy. Symposium 30. [Concurrent Symposium Session at AHRD Annual Conference, 2000.

    ERIC Educational Resources Information Center

    2000

    This packet contains four papers on organizational structure and strategy from a symposium on human resource development (HRD). The first paper, "Exploring Alignment: A Comparative Case Study of Alignment in Two Organizations" (Steven W. Semler), reports on a case study that compared the results of an alignment measurement instrument…

  7. Microteaching Lesson Study: Mentor Interaction Structure and Its Relation to Elementary Preservice Mathematics Teacher Knowledge Development

    ERIC Educational Resources Information Center

    Molina, Roxanne V.

    2012-01-01

    This study investigated Microteaching Lesson Study (MLS) and three possible MLS mentor interaction structures during the debriefing sessions in relation to elementary preservice teacher development of knowledge for teaching. One hundred three elementary preservice teachers enrolled in five different sections of a mathematics methods course at a…

  8. Cardiovascular disease medication health literacy among Indigenous peoples: design and protocol of an intervention trial in Indigenous primary care services.

    PubMed

    Crengle, Sue; Smylie, Janet; Kelaher, Margaret; Lambert, Michelle; Reid, Susan; Luke, Joanne; Anderson, Ian; Harré Hindmarsh, Jennie; Harwood, Matire

    2014-07-12

    Cardiovascular diseases (CVD) are leading causes of mortality and morbidity among Indigenous people in New Zealand, Australia and Canada and are a major driver of the inequities in life expectancy between Indigenous and non-Indigenous people in these countries. Evidence-based pharmaceutical management of CVD can significantly reduce mortality and morbidity for persons diagnosed with CVD or for those at intermediate or high risk of CVD. Health literacy has been identified as a major barrier in the communication and implementation of appropriate pharmaceutical management plans for CVD. Addressing health literacy is particularly relevant in Indigenous populations where there are unique health and adult literacy challenges. This study will examine the effect of a customized, structured CVD medication programme, delivered by health professionals, on the health literacy of Indigenous people with, or at risk, of CVD. Primary outcomes are patient's knowledge about CVD medications; secondary outcomes examine changes in health literacy skills and practices. The study will employ a multi-site pre-post design with multiple measurement points to assess intervention efficacy. Participants will be recruited from four Indigenous primary care services in Australia, Canada and New Zealand. Three educational sessions will be delivered over four weeks. A tablet application will support the education sessions and produce a customized pill card for each participant. Participants will be provided with written information about CVD medications. Medication knowledge scores, and specific health literacy skills and practices will be assessed before and after the three sessions. Statistical analyses will identify significant changes in outcomes over each session, and from the pre-session one to post-session three time points. This study will make an important contribution to understanding the effect of a structured primary care-based intervention on CVD health literacy in Indigenous populations. The study also illustrates the incorporation of Indigenous health research principles and processes in clinical trials and provides insights that may be useful in other contexts. Australian and New Zealand Clinical Trials Register (ACTRN12612001309875; date of registration 18/12/2012).

  9. NNDC Stand: Activities and Services of the National Nuclear Data Center

    NASA Astrophysics Data System (ADS)

    Pritychenko, B.; Arcilla, R.; Burrows, T. W.; Dunford, C. L.; Herman, M. W.; McLane, V.; Obložinský, P.; Sonzogni, A. A.; Tuli, J. K.; Winchell, D. F.

    2005-05-01

    The National Nuclear Data Center (NNDC) collects, evaluates, and disseminates nuclear physics data for basic nuclear research, applied nuclear technologies including energy, shielding, medical and homeland security. In 2004, to answer the needs of nuclear data users community, NNDC completed a project to modernize data storage and management of its databases and began offering new nuclear data Web services. The principles of database and Web application development as well as related nuclear reaction and structure database services are briefly described.

  10. The oxygen isotopes

    NASA Astrophysics Data System (ADS)

    Alex Brown, B.

    The properties of the oxygen isotopes provide diverse examples of progress made in experiments and theory. This chain of isotopes has been studied from beyond the proton drip line in 12O to beyond the neutron drip line in 25,26O. This short survey starts with the microscopic G matrix approach for 18O of Kuo and Brown in the 1960's and shows how theory has evolved. The nuclear structure around the doubly-magic nucleus 24O is particularly simple in terms of the nuclear shell model. The nuclear structure around the doubly-magic nucleus 16O exhibits the coexistence of single-particle and collective structure.

  11. Nuclear spectroscopic studies. Progress report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bingham, C.R.; Guidry, M.W.; Riedinger, L.L.

    1994-02-18

    The Nuclear Physics group at UTK is involved in heavy-ion physics including both nuclear structure and reaction mechanisms. During the last year experimental work has been in 3 broad areas: structure of nuclei at high angular momentum, structure of nuclei far from stability, and ultra-relativistic heavy-ion physics. Results in these areas are described in this document under: properties of high-spin states, study of low-energy levels of nuclei far from stability, and high-energy heavy-ion physics (PHENIX, etc.). Another important component of the work is theoretical interpretation of experimental results (Joint Institute for Heavy Ion Research).

  12. An optimal transportation approach for nuclear structure-based pathology.

    PubMed

    Wang, Wei; Ozolek, John A; Slepčev, Dejan; Lee, Ann B; Chen, Cheng; Rohde, Gustavo K

    2011-03-01

    Nuclear morphology and structure as visualized from histopathology microscopy images can yield important diagnostic clues in some benign and malignant tissue lesions. Precise quantitative information about nuclear structure and morphology, however, is currently not available for many diagnostic challenges. This is due, in part, to the lack of methods to quantify these differences from image data. We describe a method to characterize and contrast the distribution of nuclear structure in different tissue classes (normal, benign, cancer, etc.). The approach is based on quantifying chromatin morphology in different groups of cells using the optimal transportation (Kantorovich-Wasserstein) metric in combination with the Fisher discriminant analysis and multidimensional scaling techniques. We show that the optimal transportation metric is able to measure relevant biological information as it enables automatic determination of the class (e.g., normal versus cancer) of a set of nuclei. We show that the classification accuracies obtained using this metric are, on average, as good or better than those obtained utilizing a set of previously described numerical features. We apply our methods to two diagnostic challenges for surgical pathology: one in the liver and one in the thyroid. Results automatically computed using this technique show potentially biologically relevant differences in nuclear structure in liver and thyroid cancers.

  13. An optimal transportation approach for nuclear structure-based pathology

    PubMed Central

    Wang, Wei; Ozolek, John A.; Slepčev, Dejan; Lee, Ann B.; Chen, Cheng; Rohde, Gustavo K.

    2012-01-01

    Nuclear morphology and structure as visualized from histopathology microscopy images can yield important diagnostic clues in some benign and malignant tissue lesions. Precise quantitative information about nuclear structure and morphology, however, is currently not available for many diagnostic challenges. This is due, in part, to the lack of methods to quantify these differences from image data. We describe a method to characterize and contrast the distribution of nuclear structure in different tissue classes (normal, benign, cancer, etc.). The approach is based on quantifying chromatin morphology in different groups of cells using the optimal transportation (Kantorovich-Wasserstein) metric in combination with the Fisher discriminant analysis and multidimensional scaling techniques. We show that the optimal transportation metric is able to measure relevant biological information as it enables automatic determination of the class (e.g. normal vs. cancer) of a set of nuclei. We show that the classification accuracies obtained using this metric are, on average, as good or better than those obtained utilizing a set of previously described numerical features. We apply our methods to two diagnostic challenges for surgical pathology: one in the liver and one in the thyroid. Results automatically computed using this technique show potentially biologically relevant differences in nuclear structure in liver and thyroid cancers. PMID:20977984

  14. 10 CFR 50.69 - Risk-informed categorization and treatment of structures, systems and components for nuclear...

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ..., systems and components for nuclear power reactors. 50.69 Section 50.69 Energy NUCLEAR REGULATORY..., systems and components for nuclear power reactors. (a) Definitions. Risk-Informed Safety Class (RISC)-1... holder of a license to operate a light water reactor (LWR) nuclear power plant under this part; a holder...

  15. 10 CFR 50.69 - Risk-informed categorization and treatment of structures, systems and components for nuclear...

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ..., systems and components for nuclear power reactors. 50.69 Section 50.69 Energy NUCLEAR REGULATORY..., systems and components for nuclear power reactors. (a) Definitions. Risk-Informed Safety Class (RISC)-1... holder of a license to operate a light water reactor (LWR) nuclear power plant under this part; a holder...

  16. 10 CFR 50.69 - Risk-informed categorization and treatment of structures, systems and components for nuclear...

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ..., systems and components for nuclear power reactors. 50.69 Section 50.69 Energy NUCLEAR REGULATORY..., systems and components for nuclear power reactors. (a) Definitions. Risk-Informed Safety Class (RISC)-1... holder of a license to operate a light water reactor (LWR) nuclear power plant under this part; a holder...

  17. MO-AB-207-02: ACR Update in MR

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Price, R.

    2015-06-15

    A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date asmore » the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program.« less

  18. MO-AB-207-04: ACR Update in Mammography

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Berns, E.

    2015-06-15

    A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date asmore » the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program.« less

  19. MO-AB-207-01: ACR Update in CT

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    McNitt-Gray, M.

    2015-06-15

    A goal of an imaging accreditation program is to ensure adequate image quality, verify appropriate staff qualifications, and to assure patient and personnel safety. Currently, more than 35,000 facilities in 10 modalities have been accredited by the American College of Radiology (ACR), making the ACR program one of the most prolific accreditation options in the U.S. In addition, ACR is one of the accepted accreditations required by some state laws, CMS/MIPPA insurance and others. Familiarity with the ACR accreditation process is therefore essential to clinical diagnostic medical physicists. Maintaining sufficient knowledge of the ACR program must include keeping up-to-date asmore » the various modality requirements are refined to better serve the goals of the program and to accommodate newer technologies and practices. This session consists of presentations from authorities in four ACR accreditation modality programs, including magnetic resonance imaging, computed tomography, nuclear medicine, and mammography. Each speaker will discuss the general components of the modality program and address any recent changes to the requirements. Learning Objectives: To understand the requirements of the ACR MR Accreditation program. The discussion will include accreditation of whole-body general purpose magnets, dedicated extremity systems well as breast MRI accreditation. Anticipated updates to the ACR MRI Quality Control Manual will also be reviewed. To understand the requirements of the ACR CT accreditation program, including updates to the QC manual as well as updates through the FAQ process. To understand the requirements of the ACR nuclear medicine accreditation program, and the role of the physicist in annual equipment surveys and the set up and supervision of the routine QC program. To understand the current ACR MAP Accreditation requirement and present the concepts and structure of the forthcoming ACR Digital Mammography QC Manual and Program.« less

  20. Embedded random matrix ensembles from nuclear structure and their recent applications

    NASA Astrophysics Data System (ADS)

    Kota, V. K. B.; Chavda, N. D.

    Embedded random matrix ensembles generated by random interactions (of low body rank and usually two-body) in the presence of a one-body mean field, introduced in nuclear structure physics, are now established to be indispensable in describing statistical properties of a large number of isolated finite quantum many-particle systems. Lie algebra symmetries of the interactions, as identified from nuclear shell model and the interacting boson model, led to the introduction of a variety of embedded ensembles (EEs). These ensembles with a mean field and chaos generating two-body interaction generate in three different stages, delocalization of wave functions in the Fock space of the mean-field basis states. The last stage corresponds to what one may call thermalization and complex nuclei, as seen from many shell model calculations, lie in this region. Besides briefly describing them, their recent applications to nuclear structure are presented and they are (i) nuclear level densities with interactions; (ii) orbit occupancies; (iii) neutrinoless double beta decay nuclear transition matrix elements as transition strengths. In addition, their applications are also presented briefly that go beyond nuclear structure and they are (i) fidelity, decoherence, entanglement and thermalization in isolated finite quantum systems with interactions; (ii) quantum transport in disordered networks connected by many-body interactions with centrosymmetry; (iii) semicircle to Gaussian transition in eigenvalue densities with k-body random interactions and its relation to the Sachdev-Ye-Kitaev (SYK) model for majorana fermions.

  1. INDC International Nuclear Data Committee

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nichols, A.; McCutchan, E.; Dimitriou, P.

    The 22nd meeting of the International Network of Nuclear Structure and Decay Data Evaluators was convened at the Lawrence Berkeley National Laboratory, Berkeley, USA, from 22 to 26 May 2017 under the auspices of the IAEA Nuclear Data Section. This meeting was attended by 38 scientists from 12 Member States and the IAEA, all of whom are concerned primarily with the measurement, evaluation and dissemination of nuclear structure and decay data. A summary of the meeting, data centre reports, various proposals considered, technical discussions, actions agreed by the participants, and the resulting recommendations/conclusions are presented within this document.

  2. Handbook explaining the fundamentals of nuclear and atomic physics

    NASA Technical Reports Server (NTRS)

    Hanlen, D. F.; Morse, W. J.

    1969-01-01

    Indoctrination document presents nuclear, reactor, and atomic physics in an easy, straightforward manner. The entire subject of nuclear physics including atomic structure ionization, isotopes, radioactivity, and reactor dynamics is discussed.

  3. Working session 3: Tubing integrity

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cueto-Felgueroso, C.; Strosnider, J.

    1997-02-01

    Twenty-three individuals representing nine countries (Belgium, Canada, the Czech Republic, France, Japan, the Slovak Republic, Spain, the UK, and the US) participated in the session on tube integrity. These individuals represented utilities, vendors, consultants and regulatory authorities. The major subjects discussed by the group included overall objectives of managing steam generator tube degradation, necessary elements of a steam generator degradation management program, the concept of degradation specific management, structural integrity evaluations, leakage evaluations, and specific degradation mechanisms. The group`s discussions on these subjects, including conclusions and recommendations, are summarized in this article.

  4. The International Conference on Intelligent Biology and Medicine (ICIBM) 2016: from big data to big analytical tools.

    PubMed

    Liu, Zhandong; Zheng, W Jim; Allen, Genevera I; Liu, Yin; Ruan, Jianhua; Zhao, Zhongming

    2017-10-03

    The 2016 International Conference on Intelligent Biology and Medicine (ICIBM 2016) was held on December 8-10, 2016 in Houston, Texas, USA. ICIBM included eight scientific sessions, four tutorials, one poster session, four highlighted talks and four keynotes that covered topics on 3D genomics structural analysis, next generation sequencing (NGS) analysis, computational drug discovery, medical informatics, cancer genomics, and systems biology. Here, we present a summary of the nine research articles selected from ICIBM 2016 program for publishing in BMC Bioinformatics.

  5. High-content image informatics of the structural nuclear protein NuMA parses trajectories for stem/progenitor cell lineages and oncogenic transformation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vega, Sebastián L.; Liu, Er; Arvind, Varun

    Stem and progenitor cells that exhibit significant regenerative potential and critical roles in cancer initiation and progression remain difficult to characterize. Cell fates are determined by reciprocal signaling between the cell microenvironment and the nucleus; hence parameters derived from nuclear remodeling are ideal candidates for stem/progenitor cell characterization. Here we applied high-content, single cell analysis of nuclear shape and organization to examine stem and progenitor cells destined to distinct differentiation endpoints, yet undistinguishable by conventional methods. Nuclear descriptors defined through image informatics classified mesenchymal stem cells poised to either adipogenic or osteogenic differentiation, and oligodendrocyte precursors isolated from different regionsmore » of the brain and destined to distinct astrocyte subtypes. Nuclear descriptors also revealed early changes in stem cells after chemical oncogenesis, allowing the identification of a class of cancer-mitigating biomaterials. To capture the metrology of nuclear changes, we developed a simple and quantitative “imaging-derived” parsing index, which reflects the dynamic evolution of the high-dimensional space of nuclear organizational features. A comparative analysis of parsing outcomes via either nuclear shape or textural metrics of the nuclear structural protein NuMA indicates the nuclear shape alone is a weak phenotypic predictor. In contrast, variations in the NuMA organization parsed emergent cell phenotypes and discerned emergent stages of stem cell transformation, supporting a prognosticating role for this protein in the outcomes of nuclear functions. - Highlights: • High-content analysis of nuclear shape and organization classify stem and progenitor cells poised for distinct lineages. • Early oncogenic changes in mesenchymal stem cells (MSCs) are also detected with nuclear descriptors. • A new class of cancer-mitigating biomaterials was identified based on image informatics. • Textural metrics of the nuclear structural protein NuMA are sufficient to parse emergent cell phenotypes.« less

  6. Center for Theoretical Underground Physics and Related Areas – CETUP*2016 Summer Program

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Szczerbinska, Barbara

    For last six years Center for Theoretical Underground Physics and Related Areas (CETUP*) successfully provided a stimulating environment for creative thinking and open communication between researches of varying ages and nationalities in dynamic atmosphere of intense scientific interactions. Ongoing and proposed Neutrino and Dark Matter experiments are expected to unveil the answers to fundamental questions about the Universe. CETUP*2016 was focused exactly on these subjects bringing together experts in dark matter, neutrino physics, particle and nuclear physics, astrophysics and cosmology from around the world. Scientists invited to participate in the program not only provided theoretical support to the underground science,more » but they also examined core questions including: What is the nature of dark matter?, What is the origin of the neutrino masses?, How well do we know the neutrino parameters?, How have neutrinos shaped the evolution of the universe?, , What are the fundamental underlying symmetries of the Universe? Is there a Grand Unified Theory of the Universe? and many others. The 2016 CETUP* summer program consisted of three sessions (June 6 – July 16, 2016) covering various aspects of theoretical and experimental neutrino physics, unification and dark matter. The two week long session on Physics and Instrumentation of the Near Detector for the Long-Baseline Neutrino Experiments (June 6 – June 16) was followed by the two week long Neutrino Physics/Unification session: “From Grand Unification to String Theory and Back” (June 20 – July 2). The program ended with two week long session on Dark Matter Physics (July 4 – July 16). This six-week long program allowed for thorough discussions and an effective and comprehensive analysis of topics related to Dark Matter, Dark Energy, Neutrino Physics including astrophysical neutrinos, near and far detector physics, neutrino interactions, Higgs Boson, Inflation, Leptogenesis and many others that will advance the knowledge in particle and nuclear physics, astrophysics and cosmology. The scientific program usually consisted of 2-3 hour-long talks on selected subjects in dark matter and neutrino physics from both theoretical and experimental perspective and followed by extended in depth discussions. The format of the program accommodated separate discussion sessions where the outstanding issues of the disciplines were explored, for example: The Future of Large Physics Projects in the US, and the Role of Theory in the Future of US Physics. 2016 CETUP* summer program was attended by over 70 national and international scientists (including 17 graduate students, 16 postdocs and 39 senior scientists) from over 48 different universities and laboratories. CETUP* participants were very active senior and junior members of the community in order to make the discussions informative and productive. CETUP* 2016 provided a stimulating venue for the exchange of scientific ideas among experts in dark matter, neutrino physics, particle physics, astrophysics and cosmology. During Dark Matter session thirty-seven scientific talks and extended discussions were presented. Twenty-nine talks and discussions were conducted during the Neutrino Physics sessions by international Neutrino Physics experts. The power point presentations for the talks and discussions can be found on the CETUP* website: http://research.dsu.edu/cetup/agenda.aspx. Based on the collaborations established during CETUP* already ten preprints were published and many more are in preparation: https://research.dsu.edu/cetup/preprints.aspx?cetupYear=2016. The proceedings from CETUP*2016 are in preparation to be published by American Institute of Physics in summer 2017. Multiple outreach efforts aimed to share the excitement of the research with K-12, teachers, undergraduate and graduate students as well as the general public.« less

  7. Emerging Applications of Ceramic and Metal Matrix Composites

    NASA Astrophysics Data System (ADS)

    Krishnamoorthy, Divya; Ramolina, Dheeyana; Sandou, Sherleena

    2012-07-01

    Almost 500 papers were presented during the 43 sessions of the 27th Annual Cocoa Beach Conference & Exposition on Advanced Ceramics & Composites, which was organized by the Engineering Ceramics Division of the American Ceramic Society and sponsored by several federal agencies: NASA Glenn Research Center, the Army Research Office, the Department of Energy, and the Air Force Office of Scientific Research. Many of these papers focused on composites, both ceramic and metal matrix, and discussed mechanical behavior, design, fibers/interfaces, processing, and applications. Potential applications under development include components for armor, nuclear energy, and automobiles. A few of these applications have reached commercialization.

  8. S. 1626: This Act may be cited as the Mickey Leland Minority Economic Impact Revitalization Act. Introduced in the Senate of the United States, One Hundredth First Congress, First Session, September 14, 1989

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    1989-01-01

    S. 1626 is a bill to establish within the Office of Minority Economic Impact of the Department of Energy (DOE) programs involving loans and grants to enhance the development and operation of minority business enterprises with respect to energy-related business, to amend the Nuclear Waste Policy Act of 1982 to permit the investment of certain funds in the Minority Bank Deposit Program of the Department of the Treasury, and for other purposes.

  9. Conference on Intelligent Robotics in Field, Factory, Service, and Space (CIRFFSS 1994), volume 1

    NASA Technical Reports Server (NTRS)

    Erickson, Jon D. (Editor)

    1994-01-01

    The AIAA/NASA Conference on Intelligent Robotics in Field, Factory, Service, and Space (CIRFFSS '94) was originally proposed because of the strong belief that America's problems of global economic competitiveness and job creation and preservation can partly be solved by the use of intelligent robotics, which are also required for human space exploration missions. Individual sessions addressed nuclear industry, agile manufacturing, security/building monitoring, on-orbit applications, vision and sensing technologies, situated control and low-level control, robotic systems architecture, environmental restoration and waste management, robotic remanufacturing, and healthcare applications.

  10. James B. Edwards nomination. Hearing before the Committee on Energy and Natural Resources, United States Senate, Ninety-Seventh Congress, First Session, January 12, 1981

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    Thirteen witnesses spoke at a January 12, 1981 hearing on the nomination of James B. Edwards for the position of Secretary of Energy. They reviewed Gov. Edwards' career and qualifications in light of US economic and energy needs. The senators of eight states emphasized the urgency of appropriate energy policies. Their statements are followed by the comments and responses of the nominee. Further testimony was given by representatives of the Democratic party, nuclear- and fusion-energy proponents, and the Environmental Policy Center. (DCK)

  11. The Advanced Test Reactor National Scientific User Facility Advancing Nuclear Technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    T. R. Allen; J. B. Benson; J. A. Foster

    2009-05-01

    To help ensure the long-term viability of nuclear energy through a robust and sustained research and development effort, the U.S. Department of Energy (DOE) designated the Advanced Test Reactor and associated post-irradiation examination facilities a National Scientific User Facility (ATR NSUF), allowing broader access to nuclear energy researchers. The mission of the ATR NSUF is to provide access to world-class nuclear research facilities, thereby facilitating the advancement of nuclear science and technology. The ATR NSUF seeks to create an engaged academic and industrial user community that routinely conducts reactor-based research. Cost free access to the ATR and PIE facilities ismore » granted based on technical merit to U.S. university-led experiment teams conducting non-proprietary research. Proposals are selected via independent technical peer review and relevance to DOE mission. Extensive publication of research results is expected as a condition for access. During FY 2008, the first full year of ATR NSUF operation, five university-led experiments were awarded access to the ATR and associated post-irradiation examination facilities. The ATR NSUF has awarded four new experiments in early FY 2009, and anticipates awarding additional experiments in the fall of 2009 as the results of the second 2009 proposal call. As the ATR NSUF program mature over the next two years, the capability to perform irradiation research of increasing complexity will become available. These capabilities include instrumented irradiation experiments and post-irradiation examinations on materials previously irradiated in U.S. reactor material test programs. The ATR critical facility will also be made available to researchers. An important component of the ATR NSUF an education program focused on the reactor-based tools available for resolving nuclear science and technology issues. The ATR NSUF provides education programs including a summer short course, internships, faculty-student team projects and faculty/staff exchanges. In June of 2008, the first week-long ATR NSUF Summer Session was attended by 68 students, university faculty and industry representatives. The Summer Session featured presentations by 19 technical experts from across the country and covered topics including irradiation damage mechanisms, degradation of reactor materials, LWR and gas reactor fuels, and non-destructive evaluation. High impact research results from leveraging the entire research infrastructure, including universities, industry, small business, and the national laboratories. To increase overall research capability, ATR NSUF seeks to form strategic partnerships with university facilities that add significant nuclear research capability to the ATR NSUF and are accessible to all ATR NSUF users. Current partner facilities include the MIT Reactor, the University of Michigan Irradiated Materials Testing Laboratory, the University of Wisconsin Characterization Laboratory, and the University of Nevada, Las Vegas transmission Electron Microscope User Facility. Needs for irradiation of material specimens at tightly controlled temperatures are being met by dedication of a large in-pile pressurized water loop facility for use by ATR NSUF users. Several environmental mechanical testing systems are under construction to determine crack growth rates and fracture toughness on irradiated test systems.« less

  12. Peering into a Chilean black box: parental storytelling in pediatric genetic counseling.

    PubMed

    Ordonez, Jessica; Margarit, Sonia; Downs, Katy; Yashar, Beverly M

    2013-12-01

    While genetic counseling has expanded to multiple international settings, research about providing culturally sensitive services to non-U.S. patients is limited. To gain insights, we utilized a process study to explore parental communication in pediatric genetics clinics in Chile. We utilized a phenomenological hermeneutic approach to assess storytelling in six pediatric sessions that were conducted in Spanish, and translated into English. The majority of the sessions focused on information gathering (35 %), and providing medical (20 %) and genetics education (18 %). The 14 instances of storytelling we identified usually emerged during information gathering, genetics education, and the closing of the session. Stories illustrated parental efforts to create a cognitive and emotional context for their child's genetic diagnosis. Parents emerged as competent caregivers who discussed the role of the child as a social being in the family and the larger community. Our analysis found that genetic counseling sessions in the U.S. and Chile are structured similarly and although communication is not a balanced process, parents use storytelling to participate as active agents in the session. Via storytelling, we learned that parents are working to understand and gain control over their child's genetic diagnosis by relying on mechanisms that extend beyond the genetics appointment.

  13. Orbitofrontal cortex inactivation impairs between- but not within-session Pavlovian extinction: an associative analysis.

    PubMed

    Panayi, Marios C; Killcross, Simon

    2014-02-01

    The orbitofrontal cortex (OFC) is argued to be the neural locus of Pavlovian outcome expectancies. Reinforcement learning theories argue that extinction learning in Pavlovian procedures is caused by the discrepancy between the expected value of the outcome (US) that is elicited by a predictive stimulus (CS), and the lack of experienced US. If the OFC represents Pavlovian outcome expectancies that are necessary for extinction learning, then disrupting OFC function prior to extinction training should impair extinction learning. This was tested. In experiment 1, Long Evans rats received infusions of saline or muscimol targeting the lateral OFC prior to three appetitive Pavlovian extinction sessions. Muscimol infused into the OFC disrupted between-session but not within-session extinction behaviour. This finding was not due to muscimol infusions disrupting the memory consolidation process per se as there was no effect of muscimol infusion when administered immediately post session (experiment 2). These findings support a role for the OFC in representing outcome expectancies that are necessary for learning. A number of ways in which disrupting outcome expectancy information might block learning will be discussed in the context of traditional associative learning theories and the associative structures they depend on. Copyright © 2013 Elsevier Inc. All rights reserved.

  14. Genetics Home Reference: triple A syndrome

    MedlinePlus

    ... understood. Within cells, ALADIN is found in the nuclear envelope, the structure that surrounds the nucleus and ... protein from reaching its proper location in the nuclear envelope. The absence of ALADIN in the nuclear ...

  15. THE AIMS AND ACTIVITIES OF THE INTERNATIONAL NETWORK OF NUCLEAR STRUCTURE AND DECAY DATA EVALUATORS.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    NICHOLS,A.L.; TULI, J.K.

    International Network of Nuclear Structure and Decay Data (NSDD) Evaluators consists of a number of evaluation groups and data service centers in several countries that appreciate the merits of working together to maintain and ensure the quality and comprehensive content of the ENSDF database (Evaluated Nuclear Structure Data File). Biennial meetings of the network are held under the auspices of the International Atomic Energy Agency (IAEA) to assign evaluation responsibilities, monitor progress, discuss improvements and emerging difficulties, and agree on actions to be undertaken by individual members. The evaluated data and bibliographic details are made available to users via variousmore » media, such as the journals ''Nuclear Physics A'' and ''Nuclear Data Sheets'', the World Wide Web, on CD-ROM, wall charts of the nuclides and ''Nuclear Wallet Cards''. While the ENSDF master database is maintained by the US National Nuclear Data Center at the Brookhaven National Laboratory, these data are also available from other nuclear data centers including the IAEA Nuclear Data Section. The Abdus Salam International Centre for Theoretical Physics (ICTP), Trieste, Italy, in cooperation with the IAEA, organizes workshops on NSDD at regular intervals. The primary aims of these particular workshops are to provide hands-on training in the data evaluation processes, and to encourage new evaluators to participate in NSDD activities. The technical contents of these NSDD workshops are described, along with the rationale for the inclusion of various topics.« less

  16. 76 FR 2725 - Draft Regulatory Guide: Issuance, Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-14

    .... The draft regulatory guide, entitled, ``Inspection of Water-Control Structures Associated with Nuclear... and surveillance program for dams, slopes, canals, and other water-control structures associated with emergency cooling water systems or flood protection of nuclear power plants. II. Further Information The NRC...

  17. Hadronic and nuclear interactions in QCD

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Not Available

    Despite the evidence that QCD - or something close to it - gives a correct description of the structure of hadrons and their interactions, it seems paradoxical that the theory has thus far had very little impact in nuclear physics. One reason for this is that the application of QCD to distances larger than 1 fm involves coherent, non-perturbative dynamics which is beyond present calculational techniques. For example, in QCD the nuclear force can evidently be ascribed to quark interchange and gluon exchange processes. These, however, are as complicated to analyze from a fundamental point of view as is themore » analogous covalent bond in molecular physics. Since a detailed description of quark-quark interactions and the structure of hadronic wavefunctions is not yet well-understood in QCD, it is evident that a quantitative first-principle description of the nuclear force will require a great deal of theoretical effort. Another reason for the limited impact of QCD in nuclear physics has been the conventional assumption that nuclear interactions can for the most part be analyzed in terms of an effective meson-nucleon field theory or potential model in isolation from the details of short distance quark and gluon structure of hadrons. These lectures, argue that this view is untenable: in fact, there is no correspondence principle which yields traditional nuclear physics as a rigorous large-distance or non-relativistic limit of QCD dynamics. On the other hand, the distinctions between standard nuclear physics dynamics and QCD at nuclear dimensions are extremely interesting and illuminating for both particle and nuclear physics.« less

  18. The Structure of Active Galactic Nuclei

    NASA Technical Reports Server (NTRS)

    Kriss, Gerard A.

    1997-01-01

    We are continuing our systematic investigation of the nuclear structure of nearby active galactic nuclei (AGN). Upon completion, our study will characterize hypothetical constructs such as narrow-line clouds, obscuring tori, nuclear gas disks. and central black holes with physical measurements for a complete sample of nearby AGN. The major scientific goals of our program are: (1) the morphology of the NLR; (2) the physical conditions and dynamics of individual clouds in the NLR; (3) the structure and physical conditions of the warm reflecting gas; (4) the structure of the obscuring torus; (5) the population and morphology of nuclear disks/tori in AGN; (6) the physical conditions in nuclear disks; and (7) the masses of central black holes in AGN. We will use the Hubble Space Telescope (HST) to obtain high-resolution images and spatially resolved spectra. Far-UV spectroscopy of emission and absorption in the nuclear regions using HST/FOS and the Hopkins Ultraviolet Telescope (HUT) will help establish physical conditions in the absorbing and emitting gas. By correlating the dynamics and physical conditions of the gas with the morphology revealed through our imaging program, we will be able to examine mechanisms for fueling the central engine and transporting angular momentum. The kinematics of the nuclear gas disks may enable us to measure the mass of the central black hole. Contemporaneous X-ray observations using ASCA will further constrain the ionization structure of any absorbing material. Monitoring of variability in the UV and X-ray absorption will be used to determine the location of the absorbing gas, possibly in the outflowing warm reflecting gas, or the broad-line region, or the atmosphere of the obscuring torus. Supporting ground-based observations in the optical, near-IR, imaging polarimetry, and the radio will complete our picture of the nuclear structures. With a comprehensive survey of these characteristics in a complete sample of nearby AGN, our conclusions should be more reliably extended to AGN as a class.

  19. Providing rapid feedback to residents on their teaching skills: an educational strategy for contemporary trainees

    PubMed Central

    Baer, Tamar G.; Gershel, Jeffrey C.

    2016-01-01

    Objectives The objective of this study was to assess the attitudes of contemporary residents toward receiving rapid feedback on their teaching skills from their medical student learners. Methods Participants consisted of 20 residents in their second post-graduate training year. These residents facilitated 44 teaching sessions with medical students within our Resident-as-Teacher program. Structured, written feedback from students was returned to the resident within 3 days following each session. Residents completed a short survey about the utility of the feedback, whether they would make a change to future teaching sessions based on the feedback, and what specifically they might change. The survey utilized a 4-point scale (“Not helpful/likely=1” to “Very helpful/likely=4”), and allowed for one free-text response. Free-text responses were hand-coded and underwent qualitative analysis to identify themes.   Results There were 182 student feedback encounters resulting from 44 teaching sessions. The survey response rate was 73% (32/44). Ninety-four percent of residents rated the rapid feedback as “very helpful,” and 91% would “very likely” make a change to subsequent sessions based on student feedback. Residents’ proposed changes included modifications to session content and/or their personal teaching style.    Conclusions Residents found that rapid feedback received from medical student learners was highly valuable to them in their roles as teachers. A rapid feedback strategy may facilitate an optimal educational environment for contemporary trainees. PMID:26995390

  20. Identifying moderators of the adherence-outcome relation in cognitive therapy for depression.

    PubMed

    Sasso, Katherine E; Strunk, Daniel R; Braun, Justin D; DeRubeis, Robert J; Brotman, Melissa A

    2015-10-01

    Little is known about the influence of patients' pretreatment characteristics on the adherence-outcome relation in cognitive therapy (CT) for depression. In a sample of 57 depressed adults participating in CT, the authors examined interactions between pretreatment patient characteristics and therapist adherence in predicting session-to-session symptom change. Using items from the Collaborative Study Psychotherapy Rating Scale, the authors assessed 3 facets of therapist adherence: cognitive methods, negotiating/structuring, and behavioral methods/homework. Two graduate students rated Sessions 1-4 for adherence. Symptoms were assessed prior to each session with the Beck Depression Inventory-II. Moderators were assessed as part of patients' intake evaluations. After correcting for multiple comparisons, patient gender remained a significant moderator of the relationship between cognitive methods and next-session symptom change; cognitive methods more strongly predicted greater symptom improvement for women as compared to men. Pretreatment anxiety and number of prior depressive episodes were significant moderators of the relationship between behavioral methods/homework and next-session symptom change, with greater behavioral methods/homework predicting symptom improvement more strongly among patients high in pretreatment anxiety and among patients with relatively few prior depressive episodes. This is the first study to provide evidence of how therapist adherence is differentially related to outcome among depressed patients with different characteristics. If replicated, these findings may inform clinical decisions regarding the use of specific facets of adherence in CT for depression with specific patients. (c) 2015 APA, all rights reserved).

  1. Structural determination of importin alpha in complex with beak and feather disease virus capsid nuclear localization signal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Patterson, Edward I.; EH Graham Centre for Agricultural Innovation; Dombrovski, Andrew K.

    2013-09-06

    Highlights: •Circovirus capsid proteins contain large nuclear localization signals (NLS). •A method of nuclear import has not been elucidated. •Beak and feather disease virus (BFDV) capsid NLS was crystallized with importin α. •The structure showed BFDV NLS binding to the major site of importin α. •Result shows implications for mechanism of nuclear transport for all circoviruses. -- Abstract: Circoviruses represent a rapidly increasing genus of viruses that infect a variety of vertebrates. Replication requires shuttling viral molecules into the host cell nucleus, a process facilitated by capsid-associated protein (Cap). Whilst a nuclear localization signal (NLS) has been shown to mediatemore » nuclear translocation, the mode of nuclear transport remains to be elucidated. To better understand this process, beak and feather disease virus (BFDV) Cap NLS was crystallized with nuclear import receptor importin-α (Impα). Diffraction yielded structural data to 2.9 Å resolution, and the binding site on both Impα and BFDV Cap NLS were well resolved. The binding mechanism for the major site is likely conserved across circoviruses as supported by the similarity of NLSs in circovirus Caps. This finding illuminates a crucial step for infection of host cells by this viral family, and provides a platform for rational drug design against the binding interface.« less

  2. Structure-Based Low-Rank Model With Graph Nuclear Norm Regularization for Noise Removal.

    PubMed

    Ge, Qi; Jing, Xiao-Yuan; Wu, Fei; Wei, Zhi-Hui; Xiao, Liang; Shao, Wen-Ze; Yue, Dong; Li, Hai-Bo

    2017-07-01

    Nonlocal image representation methods, including group-based sparse coding and block-matching 3-D filtering, have shown their great performance in application to low-level tasks. The nonlocal prior is extracted from each group consisting of patches with similar intensities. Grouping patches based on intensity similarity, however, gives rise to disturbance and inaccuracy in estimation of the true images. To address this problem, we propose a structure-based low-rank model with graph nuclear norm regularization. We exploit the local manifold structure inside a patch and group the patches by the distance metric of manifold structure. With the manifold structure information, a graph nuclear norm regularization is established and incorporated into a low-rank approximation model. We then prove that the graph-based regularization is equivalent to a weighted nuclear norm and the proposed model can be solved by a weighted singular-value thresholding algorithm. Extensive experiments on additive white Gaussian noise removal and mixed noise removal demonstrate that the proposed method achieves a better performance than several state-of-the-art algorithms.

  3. Response of basic structural elements and B-52 structural components to simulated nuclear overpressure. Volume II-program data (basic structural elements). Final report, 1 June 1977-30 September 1979

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Syring, R.P.; Grubb, R.L.

    1979-09-30

    This document reports on the following: (1) experimental determination of the response of 16 basic structural elements and 7 B-52 components to simulated nuclear overpressure environments (utilizing Sandia Corporation's Thunderpipe Shock Tube), (2) analysis of these test specimens utilizing the NOVA-2 computer program, and (3) correlation of test and analysis results.

  4. The Role of Human Error in Design, Construction, and Reliability of Marine Structures.

    DTIC Science & Technology

    1994-10-01

    The 1979 Three Mile Island nuclear plant accident was largely a result of a failure to properly sort out and recognize critically important information...determinating the goals and objectives of the program and by evaluating and interpreting the results in terms of structural design, construction, and...67 Checking Models in Structural Design ....................................... 69 Nuclear Power Plants

  5. Two-Dimensional Nuclear Magnetic Resonance Structure Determination Module for Introductory Biochemistry: Synthesis and Structural Characterization of Lyso-Glycerophospholipids

    ERIC Educational Resources Information Center

    Garrett, Teresa A.; Rose, Rebecca L.; Bell, Sidney M.

    2013-01-01

    In this laboratory module, introductory biochemistry students are exposed to two-dimensional [superscript 1]H-nuclear magnetic resonance of glycerophospholipids (GPLs). Working in groups of three, students enzymatically synthesized and purified a variety of 2-acyl lyso GPLs. The structure of the 2-acyl lyso GPL was verified using [superscript…

  6. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Winger, Jeff Allen

    Beta-decay spectroscopy provides important information on nuclear structure and properties needed to understand topics as widely varied as fundamental nuclear astrophysics to applied nuclear reactor design. However, there are significant limitations of our knowledge due to an inability to experimentally measure everything. Therefore, it is often necessary to rely on theoretical calculations which need to be vetted with experimental results. The focus of this report will be results from experimental research performed by the Principal Investigator (PI) and his research group at Mississippi State University in which the group played the lead role in proposing, implementing, performing and analyzing themore » experiment. This research was carried out at both the National Superconduction Cyclotron Laboratory (NSCL) at Michigan State University and the Holifield Radioactive Ion Beam Facility (HRIBF) at Oak Ridge National Laboratory. The primary emphasis of the research was the use of \\bdec spectroscopy as a tool to understand the evolution of nuclear structure in neutron-rich nuclei which could then be applied to improve theory and to increase the overall knowledge of nuclear structure.« less

  7. Determination of the nuclear level densities and radiative strength function for 43 nuclei in the mass interval 28≤A≤200

    NASA Astrophysics Data System (ADS)

    Knezevic, David; Jovancevic, Nikola; Sukhovoj, Anatoly M.; Mitsyna, Ludmila V.; Krmar, Miodrag; Cong, Vu D.; Hambsch, Franz-Josef; Oberstedt, Stephan; Revay, Zsolt; Stieghorst, Christian; Dragic, Aleksandar

    2018-03-01

    The determination of nuclear level densities and radiative strength functions is one of the most important tasks in low-energy nuclear physics. Accurate experimental values of these parameters are critical for the study of the fundamental properties of nuclear structure. The step-like structure in the dependence of the level densities p on the excitation energy of nuclei Eex is observed in the two-step gamma cascade measurements for nuclei in the 28 ≤ A ≤ 200 mass region. This characteristic structure can be explained only if a co-existence of quasi-particles and phonons, as well as their interaction in a nucleus, are taken into account in the process of gamma-decay. Here we present a new improvement to the Dubna practical model for the determination of nuclear level densities and radiative strength functions. The new practical model guarantees a good description of the available intensities of the two step gamma cascades, comparable to the experimental data accuracy.

  8. The nuclear envelope as an integrator of nuclear and cytoplasmic architecture.

    PubMed

    Crisp, Melissa; Burke, Brian

    2008-06-18

    Initially perceived as little more than a container for the genome, our view of the nuclear envelope (NE) and its role in defining global nuclear architecture has evolved significantly in recent years. The recognition that certain human diseases arise from defects in NE components has provided new insight into its structural and regulatory functions. In particular, NE defects associated with striated muscle disease have been shown to cause structural perturbations not just of the nucleus itself but also of the cytoplasm. It is now becoming increasingly apparent that these two compartments display co-dependent mechanical properties. The identification of cytoskeletal binding complexes that localize to the NE now reveals a molecular framework that can seamlessly integrate nuclear and cytoplasmic architecture.

  9. Intensity-Modulated Radiation Therapy (IMRT)

    MedlinePlus

    ... specialized training in the field of radiation oncology physics, ensures the linear accelerator delivers the precise radiation ... critical normal structures, as well as the patient's health. Typically, patients are scheduled for IMRT sessions five ...

  10. The Washington University Central Neuroimaging Data Archive

    PubMed Central

    Gurney, Jenny; Olsen, Timothy; Flavin, John; Ramaratnam, Mohana; Archie, Kevin; Ransford, James; Herrick, Rick; Wallace, Lauren; Cline, Jeanette; Horton, Will; Marcus, Daniel S

    2016-01-01

    Since the early 2000’s, much of the neuroimaging work at Washington University (WU) has been facilitated by the Central Neuroimaging Data Archive (CNDA), an XNAT-based imaging informatics system. The CNDA is uniquely related to XNAT, as it served as the original codebase for the XNAT open source platform. The CNDA hosts data acquired in over 1000 research studies, encompassing 36,000 subjects and more than 60,000 imaging sessions. Most imaging modalities used in modern human research are represented in the CNDA, including magnetic resonance (MR), positron emission tomography (PET), computed tomography (CT), nuclear medicine (NM), computed radiography (CR), digital radiography (DX), and ultrasound (US). However, the majority of the imaging data in the CNDA are MR and PET of the human brain. Currently, about 20% of the total imaging data in the CNDA is available by request to external researchers. CNDA’s available data includes large sets of imaging sessions and in some cases clinical, psychometric, tissue, or genetic data acquired in the study of Alzheimer’s disease, brain metabolism, cancer, HIV, sickle cell anemia, and Tourette syndrome. PMID:26439514

  11. Colloquium: Laser probing of neutron-rich nuclei in light atoms

    NASA Astrophysics Data System (ADS)

    Lu, Z.-T.; Mueller, P.; Drake, G. W. F.; Nörtershäuser, W.; Pieper, Steven C.; Yan, Z.-C.

    2013-10-01

    The neutron-rich He6 and He8 isotopes exhibit an exotic nuclear structure that consists of a tightly bound He4-like core with additional neutrons orbiting at a relatively large distance, forming a halo. Recent experimental efforts have succeeded in laser trapping and cooling these short-lived, rare helium atoms and have measured the atomic isotope shifts along the He4-He6-He8 chain by performing laser spectroscopy on individual trapped atoms. Meanwhile, the few-electron atomic structure theory, including relativistic and QED corrections, has reached a comparable degree of accuracy in the calculation of the isotope shifts. In parallel efforts, also by measuring atomic isotope shifts, the nuclear charge radii of lithium and beryllium isotopes have been studied. The techniques employed were resonance ionization spectroscopy on neutral, thermal lithium atoms and collinear laser spectroscopy on beryllium ions. Combining advances in both atomic theory and laser spectroscopy, the charge radii of these light halo nuclei have now been determined for the first time independent of nuclear structure models. The results are compared with the values predicted by a number of nuclear structure calculations and are used to guide our understanding of the nuclear forces in the extremely neutron-rich environment.

  12. Adaptation and learning: characteristic time scales of performance dynamics.

    PubMed

    Newell, Karl M; Mayer-Kress, Gottfried; Hong, S Lee; Liu, Yeou-Teh

    2009-12-01

    A multiple time scales landscape model is presented that reveals structures of performance dynamics that were not resolved in the traditional power law analysis of motor learning. It shows the co-existence of separate processes during and between practice sessions that evolve in two independent dimensions characterized by time scales that differ by about an order of magnitude. Performance along the slow persistent dimension of learning improves often as much and sometimes more during rest (memory consolidation and/or insight generation processes) than during a practice session itself. In contrast, the process characterized by the fast, transient dimension of adaptation reverses direction between practice sessions, thereby significantly degrading performance at the beginning of the next practice session (warm-up decrement). The theoretical model fits qualitatively and quantitatively the data from Snoddy's [Snoddy, G. S. (1926). Learning and stability. Journal of Applied Psychology, 10, 1-36] classic learning study of mirror tracing and other averaged and individual data sets, and provides a new account of the processes of change in adaptation and learning. 2009 Elsevier B.V. All rights reserved.

  13. Mixed methods evaluation of well-being benefits derived from a heritage-in-health intervention with hospital patients

    PubMed Central

    Paddon, Hannah L.; Thomson, Linda J.M.; Menon, Usha; Lanceley, Anne E.; Chatterjee, Helen J.

    2013-01-01

    Background This study sought to determine the effects of a heritage-in-health intervention on well-being. Benefits of arts-in-health interventions are relatively well-documented yet little robust research has been conducted using heritage-in-health interventions, such as those involving museum objects. Methods Hospital patients (n = 57) participated in semi-structured, 30–40 minute facilitated interview sessions, discussing and handling museum objects comprising selections of six artefacts and specimens loaned from archaeology, art, geology and natural history collections. Well-being measures (Positive Affect Negative Affect Scale, Visual Analogue Scales) evaluated the sessions while inductive and deductive thematic analysis investigated psycho-educational features accounting for changes. Results Comparison of pre- and post-session quantitative measures showed significant increases in well-being and happiness. Qualitative investigation revealed thinking and meaning-making opportunities for participants engaged with objects. Conclusions Heritage-in-health sessions enhanced positive mood and social interaction, endorsing the need for provision of well-being-related museum and gallery activities for socially excluded or vulnerable healthcare audiences. PMID:25621005

  14. Impact of Underwater Explosions on Concrete Bridge Foundations

    DTIC Science & Technology

    2016-06-01

    www.theconstructioncivil.org/ [16] M. Aggour, A. Hachichi and M. Mayer, “Nondestructive evaluation of timber bridge piles,” in Proceedings of a Session a Structure Congress...detonation must be executed a safe distance from any critical infrastructure to ensure the survivability of the structure . This thesis implements...be executed a safe distance from any critical infrastructure to ensure the survivability of the structure . This thesis implements the Dynamic System

  15. Crystal structure of the Xpo1p nuclear export complex bound to the SxFG/PxFG repeats of the nucleoporin Nup42p.

    PubMed

    Koyama, Masako; Hirano, Hidemi; Shirai, Natsuki; Matsuura, Yoshiyuki

    2017-10-01

    Xpo1p (yeast CRM1) is the major nuclear export receptor that carries a plethora of proteins and ribonucleoproteins from the nucleus to cytoplasm. The passage of the Xpo1p nuclear export complex through nuclear pore complexes (NPCs) is facilitated by interactions with nucleoporins (Nups) containing extensive repeats of phenylalanine-glycine (so-called FG repeats), although the precise role of each Nup in the nuclear export reaction remains incompletely understood. Here we report structural and biochemical characterization of the interactions between the Xpo1p nuclear export complex and the FG repeats of Nup42p, a nucleoporin localized at the cytoplasmic face of yeast NPCs and has characteristic SxFG/PxFG sequence repeat motif. The crystal structure of Xpo1p-PKI-Nup42p-Gsp1p-GTP complex identified three binding sites for the SxFG/PxFG repeats on HEAT repeats 14-20 of Xpo1p. Mutational analyses of Nup42p showed that the conserved serines and prolines in the SxFG/PxFG repeats contribute to Xpo1p-Nup42p binding. Our structural and biochemical data suggest that SxFG/PxFG-Nups such as Nup42p and Nup159p at the cytoplasmic face of NPCs provide high-affinity docking sites for the Xpo1p nuclear export complex in the terminal stage of NPC passage and that subsequent disassembly of the nuclear export complex facilitates recycling of free Xpo1p back to the nucleus. © 2017 Molecular Biology Society of Japan and John Wiley & Sons Australia, Ltd.

  16. Brain structural changes following adaptive cognitive training assessed by Tensor-Based Morphometry (TBM)

    PubMed Central

    Colom, Roberto; Hua, Xue; Martínez, Kenia; Burgaleta, Miguel; Román, Francisco J.; Gunter, Jeffrey L.; Carmona, Susanna; Jaeggi, Susanne M.; Thompson, Paul M.

    2016-01-01

    Tensor-Based Morphometry (TBM) allows the automatic mapping of brain changes across time building 3D deformation maps. This technique has been applied for tracking brain degeneration in Alzheimer's and other neurodegenerative diseases with high sensitivity and reliability. Here we applied TBM to quantify changes in brain structure after completing a challenging adaptive cognitive training program based on the n-back task. Twenty-six young women completed twenty-four training sessions across twelve weeks and they showed, on average, large cognitive improvements. High-resolution MRI scans were obtained before and after training. The computed longitudinal deformation maps were analyzed for answering three questions: (a) Are there differential brain structural changes in the training group as compared with a matched control group? (b) Are these changes related to performance differences in the training program? (c) Are standardized changes in a set of psychological factors (fluid and crystallized intelligence, working memory, and attention control) measured before and after training, related to structural changes in the brain? Results showed (a) greater structural changes for the training group in the temporal lobe, (b) a negative correlation between these changes and performance across training sessions (the greater the structural change, the lower the cognitive performance improvements), and (c) negligible effects regarding the psychological factors measured before and after training. PMID:27477628

  17. Nuclear structure and dynamics with density functional theory

    NASA Astrophysics Data System (ADS)

    Stetcu, Ionel

    2015-10-01

    Even in the absence of ab initio methods capable of tackling heavy nuclei without restrictions, one can obtain an ab initio description of ground-state properties by means of the density functional theory (DFT), and its extension to superfluid systems in its local variant, the superfluid local density approximation (SLDA). Information about the properties of excited states can be obtained in the same framework by using an extension to the time-dependent (TD) phenomena. Unlike other approaches in which the nuclear structure information is used as a separate input into reaction models, the TD approach treats on the same footing the nuclear structure and dynamics, and is well suited to provide more reliable description for a large number of processes involving heavy nuclei, from the nuclear response to electroweak probes, to nuclear reactions, such as neutron-induced reactions, or nuclear fusion and fission. Such processes, sometimes part of integrated nuclear systems, have important applications in astrophysics, energy production, global security, etc. In this talk, I will present the simulation of a simple reaction, that is the Coulomb excitation of a 238U nucleus, and discuss the application of the TD-DFT formalism to the description of induced fission. I gratefully acknowledge partial support of the U.S. Department of Energy through an Early Career Award of the LANL/LDRD Program.

  18. Using Objective Structured Teaching Encounters (OSTEs) to prepare chief residents to be emotionally intelligent leaders.

    PubMed

    Cerrone, Sara Ann; Adelman, Patti; Akbar, Salaahuddin; Yacht, Andrew C; Fornari, Alice

    2017-01-01

    Chief Residents must lead, manage and mentor a diverse and often large group of residents, however there is a lack of formal leadership training throughout graduate medical education. Development of a 3-part Chief Resident (CR) Program focused on leading, managing and mentoring. Each participant completes an Emotional Intelligence (EI) Inventory prior to the day-long event. Participants receive their EI scores at the beginning of the program, which features interactive sessions on leadership, management, and feedback skills. The program then reinforces the application of their new knowledge about EI through a four station OSTE (Observed Structured Teaching Encounter). CRs practice feedback and coaching skills in a simulated environment where they need to provide the context of formative feedback to a standardized resident. The aggregated mean pre-session EI score for all participants was 76.9 (an ideal score is >85). An independent-samples t-test compared the CRs' leadership and feedback performance on their first and second OSTE performance within a single afternoon session. There was a significant difference between the first OSTE performance (M = 47.92, SD = 7.8) and the second OSTE performance (M = 51.22, SD = 6.9); t (68) = 1.99, p = 0.006. These results suggest that participating in multiple OSTEs positively reinforces the core interpersonal and communication skills discussed in the didactic and practiced in the interactive portions of the program. The low mean pre-session EI score achieved by our participants supports the idea that CRs enter their new roles with a level of EI that can be enhanced. CRs had an overall positive reaction to EI and its application to the core skills addressed in the program, highlighting the fact that similar programs could be used to train early career physicians to be more skilled and comfortable with leading, managing and mentoring. CR: Chief resident; EI: Emotional intelligence; GME: Graduate medical education; OSTE: Objective structured teaching encounter.

  19. Loose Words, Not Nukes: The Impact of U.S. Nuclear Force Structure Debate on NATO Perceptions of Extended Deterrence

    DTIC Science & Technology

    2012-02-15

    institutional mechanisms that may result in uncontrollable escalation in the belief there must be an irrevocable structural element of uncertainty...intentionally downplay the role of nuclear capabilities. Current U.S. strategy documents obliquely whisper nuclear linkages (if they are mentioned at...formally distance itself from the legacy (but still operative) NATO first-use declaratory policy.11 The express U.S. distinction exposes a fault line in

  20. Toxicity of algicidal extracts from Mangrovimonas yunxiaonensis strain LY01 on a HAB causing Alexandrium tamarense.

    PubMed

    Li, Yi; Zhu, Hong; Zhang, Huajun; Chen, Zhangran; Tian, Yun; Xu, Hong; Zheng, Tianling; Zheng, Wei

    2014-08-15

    Toxicity of algicidal extracts from Mangrovimonas yunxiaonensis strain LY01 on Alexandrium tamarense were measured through studying the algicidal procedure, nuclear damage and transcription of related genes. Medium components were optimized to improve algicidal activity, and characteristics of algicidal extracts were determined. Transmission electron microscope analysis revealed that the cell structure was broken. Cell membrane integrity destruction and nuclear structure degradation were monitored using confocal laser scanning microscope, and the rbcS, hsp and proliferating cell nuclear antigen (PCNA) gene expressions were studied. Results showed that 1.0% tryptone, 0.4% glucose and 0.8% MgCl2 were the optimal nutrient sources. The algicidal extracts were heat and pH stable, non-protein and less than 1kD. Cell membrane and nuclear structure integrity were lost, and the transcription of the rbcS and PCNA genes were significantly inhibited and there was up-regulation of hsp gene expression during the exposure procedure. The algicidal extracts destroyed the cell membrane and nuclear structure integrity, inhibited related gene expression and, eventually, lead to the inhibition of algal growth. All the results may elaborate firstly the cell death process and nuclear damage in A. tamarense which was induced by algicidal extracts, and the algicidal extracts could be potentially used as bacterial control of HABs in future. Copyright © 2014 Elsevier B.V. All rights reserved.

  1. The Legnaro National Laboratories and the SPES facility: nuclear structure and reactions today and tomorrow

    NASA Astrophysics Data System (ADS)

    de Angelis, Giacomo; Fiorentini, Gianni

    2016-11-01

    There is a very long tradition of studying nuclear structure and reactions at the Legnaro National Laboratories (LNL) of the Istituto Nazionale di Fisica Nucleare (Italian Institute of Nuclear Physics). The wide expertise acquired in building and running large germanium arrays has made the laboratories one of the most advanced research centers in γ-ray spectroscopy. The ’gamma group’ has been deeply involved in all the national and international developments of the last 20 years and is currently one of the major contributors to the AGATA project, the first (together with its American counterpart GRETINA) γ-detector array based on γ-ray tracking. This line of research is expected to be strongly boosted by the coming into operation of the SPES radioactive ion beam project, currently under construction at LNL. In this report, written on the occasion of the 40th anniversary of the Nobel prize awarded to Aage Bohr, Ben R Mottelson and Leo Rainwater and particularly focused on the physics of nuclear structure, we intend to summarize the different lines of research that have guided nuclear structure and reaction research at LNL in the last decades. The results achieved have paved the way for the present SPES facility, a new laboratories infrastructure producing and accelerating radioactive ion beams of fission fragments and other isotopes.

  2. Higher Levels of Organization in the Interphase Nucleus of Cycling and Differentiated Cells

    PubMed Central

    Leitch, Andrew R.

    2000-01-01

    The review examines the structured organization of interphase nuclei using a range of examples from the plants, animals, and fungi. Nuclear organization is shown to be an important phenomenon in cell differentiation and development. The review commences by examining nuclei in dividing cells and shows that the organization patterns can be dynamic within the time frame of the cell cycle. When cells stop dividing, derived differentiated cells often show quite different nuclear organizations. The developmental fate of nuclei is divided into three categories. (i) The first includes nuclei that undergo one of several forms of polyploidy and can themselves change in structure during the course of development. Possible function roles of polyploidy is given. (ii) The second is nuclear reorganization without polyploidy, where nuclei reorganize their structure to form novel arrangements of proteins and chromosomes. (iii) The third is nuclear disintegration linked to programmed cell death. The role of the nucleus in this process is described. The review demonstrates that recent methods to probe nuclei for nucleic acids and proteins, as well as to examine their intranuclear distribution in vivo, has revealed much about nuclear structure. It is clear that nuclear organization can influence or be influenced by cell activity and development. However, the full functional role of many of the observed phenomena has still to be fully realized. PMID:10704477

  3. Modular shipbuilding and its relevance to construction of nuclear power plants. Master's thesis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Seubert, T.W.

    1988-05-01

    The modern techniques of modular shipbuilding based on the Product Work Breakdown Structure as developed at the Ishikawajima-Harima Heavy Industries Co., Ltd. of Japan are examined and compared to conventional shipbuilding methods. The application of the Product Work Breakdown Structure in the building of the U.S. Navy's DDG-51 class ship at Bath Iron Works is described and compared to Japanese shipbuilding practices. Implementation of the Product Work Breakdown Structure at Avondale Shipyards, Incorporated is discussed and compared to Bath Iron Works shipbuilding practices. A proposed generic implementation of the Product Work Breakdown Structure to the modular construction of nuclear powermore » plants is described. Specific conclusions for the application of Product Work Breakdown Structure to the construction of a light water reactor nuclear power plant are discussed.« less

  4. Viral and cellular subnuclear structures in human cytomegalovirus-infected cells.

    PubMed

    Strang, Blair L

    2015-02-01

    In human cytomegalovirus (HCMV)-infected cells, a dramatic remodelling of the nuclear architecture is linked to the creation, utilization and manipulation of subnuclear structures. This review outlines the involvement of several viral and cellular subnuclear structures in areas of HCMV replication and virus-host interaction that include viral transcription, viral DNA synthesis and the production of DNA-filled viral capsids. The structures discussed include those that promote or impede HCMV replication (such as viral replication compartments and promyelocytic leukaemia nuclear bodies, respectively) and those whose role in the infected cell is unclear (for example, nucleoli and nuclear speckles). Viral and cellular proteins associated with subnuclear structures are also discussed. The data reviewed here highlight advances in our understanding of HCMV biology and emphasize the complexity of HCMV replication and virus-host interactions in the nucleus. © 2015 The Authors.

  5. The study of structure in 224-234 thorium nuclei within the framework IBM

    NASA Astrophysics Data System (ADS)

    Lee, Su Youn; Lee, Young Jun; Lee, J. H.

    2017-09-01

    An investigation has been made of the behaviour of nuclear structure as a function of an increase in neutron number from 224Th to 234Th. Thorium of mass number 234 is a typical rotor nucleus that can be explained by the SU(3) limit of the interacting boson model(IBM) in the algebraic nuclear model. Furthermore, 224-232Th lie on the path of the symmetry-breaking phase transition. Moreover, the nuclear structure of 224Th can be explained using X(5) symmetry. However, as 226-230Th nuclei are not fully symmetrical nuclei, they can be represented by adding a perturbed term to express symmetry breaking. Through the following three calculation steps, we identified the tendency of change in nuclear structure. Firstly, the structure of 232Th is described using the matrix elements of the Hamiltonian and the electric quadrupole operator between basis states of the SU(3) limit in IBM. Secondly, the low-lying energy levels and E2 transition ratios corresponding to the observable physical values are calculated by adding a perturbed term with the first-order Casimir operator of the U(5) limit to the SU(3) Hamiltonian in IBM. We compared the results with experimental data of 224-234Th. Lastly, the potential of the Bohr Hamiltonian is represented by a harmonic oscillator, as a result of which the structure of 224-234Th could be expressed in closed form by an approximate separation of variables. The results of these theoretical predictions clarify nuclear structure changes in Thorium nuclei over mass numbers of practical significance.

  6. Acute resistance exercise with blood flow restriction in elderly hypertensive women: haemodynamic, rating of perceived exertion and blood lactate.

    PubMed

    Pinto, Roberta R; Karabulut, Murat; Poton, Roberto; Polito, Marcos D

    2018-01-01

    This study aimed to compare haemodynamic, rating of perceived exertion and blood lactate responses during resistance exercise with blood flow restriction (BFR) compared with traditional high-intensity resistance exercise in hypertensive older women. Eighteen hypertensive women (age = 67·0 ± 1·7 years.) undertook three random sessions: (i) three sets; 10 repetitions; 20% of one repetition maximum (1RM) with BFR; (ii) three sets; 10 repetitions; 65% of 1RM; without BFR; and (iii) no-exercise with BFR. The exercise sessions were performed on knee extension equipment. Systolic (SBP) and diastolic blood pressure (DBP), heart rate (HR), stroke volume (SV) and cardiac output (CO) were significantly higher (P<0·05) in all sets of exercise sessions than the control. No statistically significant differences were detected between exercise sessions. However, SBP, DBP and systemic vascular resistance were higher (P<0·05) and SV and CO were lower (P<0·05) during the rest intervals in the session with BFR. The perceived exertion was significantly higher (P<0·01) in the 1st (4·8 ± 0·4 versus 3·1 ± 0·3), 2nd (7·3 ± 0·4 versus 5·7 ± 0·4) and 3rd sets (8·6 ± 0·5 versus 7·5 ± 0·4) of the traditional high-intensity resistance exercise compared with the exercise with BFR. Blood lactate was higher (P<0·05) in the traditional high-intensity resistance exercise (6·2 ± 0·7 mmol) than in the exercise with BFR (4·5 ± 0·4 mmol). In comparison with high-intensity resistance exercise, low-intensity resistance exercise with BFR can elicit: (i) same haemodynamic values during exercise; (ii) lower rating of perceived exertion; (iii) lower blood lactate; (iv) higher haemodynamic demand during the rest intervals. © 2016 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  7. Airframe/TPS Session

    NASA Technical Reports Server (NTRS)

    Welch, Sharon; Bowles, David

    2000-01-01

    This viewgraph presentation gives an overview of the second generation Reusable Launch Vehicle (RLV) airframe configuration, including details on the structures and materials, tanks, airframe/cryotank demonstrations, internal assemblies, weight growth and margin, and safety and cost requirements.

  8. 75 FR 39032 - Anti-Infective Drugs Advisory Committee; Notice of Meeting

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-07-07

    ..., Inc., and the requested indications of: (1) Treatment of adults with community acquired bacterial pneumonia (CABP); and (2) complicated skin and skin structure infections (cSSSI). The morning session will...

  9. Compliance & operating rules : results of a focus group

    DOT National Transportation Integrated Search

    1997-05-01

    This interim report presents the results ofa focus group session onrailroad : operating rules and compliance. In addition, it summarizes information gathered from : structured interviews with various railroad managers, government officials, and other...

  10. Nuclear Structure Research at TRIUMF

    NASA Astrophysics Data System (ADS)

    Garrett, P. E.; Andreyev, A.; Austin, R. A. E.; Ball, G. C.; Bandyopadhyay, D.; Becker, J. A.; Boston, A. J.; Chakrawarthy, R. S.; Cline, D.; Cooper, R. J.; Churchman, R.; Cross, D.; Dashdorj, D.; Demand, G. A.; Dimmock, M. R.; Drake, T. E.; Finlay, P.; Gagon-Miosan, F.; Gallant, A. T.; Green, K. L.; Grint, A. N.; Grinyer, G. F.; Hackman, G.; Harkness, L. J.; Hayes, A. B.; Kanungo, R.; Kulp, W. D.; Leach, K. G.; Lee, G.; Leslie, J. R.; Martin, J.-P.; Mattoon, C.; Mills, W. J.; Morton, A. C.; Mythili, S.; Nelson, L.; Newman, O.; Nolan, P. J.; Padilla-Rodal, E.; Pearson, C. J.; Phillips, A. A.; Porter-Peden, M.; Ressler, J. J.; Roy, R.; Ruiz, C.; Savajols, H.; Sarazin, F.; Schumaker, M. A.; Scraggs, D. P.; Scraggs, H. C.; Strange, M. D.; Svensson, C. E.; Waddington, J. C.; Wan, J. M.; Whitbeck, A.; Williams, S. J.; Wong, J.; Wood, J. L.; Wu, C. Y.; Zganjar, E. F.

    2007-04-01

    The radioactive beam laboratory at TRIUMF is currently the highest power ISOL facility in the world. Taking advantage of the high-intensity beams, major programs in nuclear astrophysics, nuclear structure, and weak interaction studies have begun. The low-energy area, ISAC-I, is capable of delivering beams up to mass 30 at approx 1.7 MeV/u or 60 keV up to the mass of the primary target, whereas ISAC-II will ultimately provide beams up to mass 150 and approx 6.5 MeV/u. Major gamma -ray spectrometers for nuclear structure research consist of the 8pi spectrometer at ISAC-I, and the TIGRESS spectrometer now being constructed for ISAC-II. Results from recent experiments investigating the beta -decay of nuclei near N=90 and Coulomb excitation of 20,21Na are presented that highlight the capabilities of the spectrometers.

  11. Analysing change in music therapy interactions of children with communication difficulties

    PubMed Central

    2016-01-01

    Music therapy has been found to improve communicative behaviours and joint attention in children with autism, but it is unclear what in the music therapy sessions drives those changes. We developed an annotation protocol and tools to accumulate large datasets of music therapy, for analysis of interaction dynamics. Analysis of video recordings of improvisational music therapy sessions focused on simple, unambiguous individual and shared behaviours: movement and facing behaviours, rhythmic activity and musical structures and the relationships between them. To test the feasibility of the protocol, early and late sessions of five client–therapist pairs were annotated and analysed to track changes in behaviours. To assess the reliability and validity of the protocol, inter-rater reliability of the annotation tiers was calculated, and the therapists provided feedback about the relevance of the analyses and results. This small-scale study suggests that there are both similarities and differences in the profiles of client–therapist sessions. For example, all therapists faced the clients most of the time, while the clients did not face back so often. Conversely, only two pairs had an increase in regular pulse from early to late sessions. More broadly, similarity across pairs at a general level is complemented by variation in the details. This perhaps goes some way to reconciling client- and context-specificity on one hand and generalizability on the other. Behavioural characteristics seem to influence each other. For instance, shared rhythmic pulse alternated with mutual facing and the occurrence of shared pulse was found to relate to the musical structure. These observations point towards a framework for looking at change in music therapy that focuses on networks of variables or broader categories. The results suggest that even when starting with simple behaviours, we can trace aspects of interaction and change in music therapy, which are seen as relevant by therapists. PMID:27069051

  12. Analysing change in music therapy interactions of children with communication difficulties.

    PubMed

    Spiro, Neta; Himberg, Tommi

    2016-05-05

    Music therapy has been found to improve communicative behaviours and joint attention in children with autism, but it is unclear what in the music therapy sessions drives those changes. We developed an annotation protocol and tools to accumulate large datasets of music therapy, for analysis of interaction dynamics. Analysis of video recordings of improvisational music therapy sessions focused on simple, unambiguous individual and shared behaviours: movement and facing behaviours, rhythmic activity and musical structures and the relationships between them. To test the feasibility of the protocol, early and late sessions of five client-therapist pairs were annotated and analysed to track changes in behaviours. To assess the reliability and validity of the protocol, inter-rater reliability of the annotation tiers was calculated, and the therapists provided feedback about the relevance of the analyses and results. This small-scale study suggests that there are both similarities and differences in the profiles of client-therapist sessions. For example, all therapists faced the clients most of the time, while the clients did not face back so often. Conversely, only two pairs had an increase in regular pulse from early to late sessions. More broadly, similarity across pairs at a general level is complemented by variation in the details. This perhaps goes some way to reconciling client- and context-specificity on one hand and generalizability on the other. Behavioural characteristics seem to influence each other. For instance, shared rhythmic pulse alternated with mutual facing and the occurrence of shared pulse was found to relate to the musical structure. These observations point towards a framework for looking at change in music therapy that focuses on networks of variables or broader categories. The results suggest that even when starting with simple behaviours, we can trace aspects of interaction and change in music therapy, which are seen as relevant by therapists. © 2016 The Authors.

  13. Dilemma-focused intervention for unipolar depression: a treatment manual.

    PubMed

    Feixas, Guillem; Compañ, Victoria

    2016-07-12

    This article introduces a new treatment protocol for depression. Based on previous research which indicated the presence of cognitive conflicts in depression, this study created an intervention manual to address these conflicts. The therapy manual for depressive patients followed the guideline for inclusion in clinical trials (stage II), which has received high recognition. A preliminary version (stage I) of this manual was formulated based on other, more general dilemma-focused therapy publications, inspired by personal construct theory (PCT), and input from clinical experience. The resulting version was then applied during the 8-session format of a pilot study with patients diagnosed with major depressive disorder or dysthymia. Finally, feedback was requested from seasoned and highly respected therapists, some of whom were familiar with PCT. According to the mentioned guideline, the intervention manual selected the theoretical framework, in this case PCT, to include its conceptualization of depression and resolution of dilemmas (to foster clinical improvement) as a main treatment goal. The manual was then contrasted with psychoanalytic psychotherapy, cognitive-behavior therapy (CBT), motivational interviewing (MI), and other similar approaches such as cognitive-analytic therapy and coherence therapy. Following these conceptual clarifications, the specific interventions included in the manual were defined according to both categories: their unique and essential components and those conceived as common psychotherapeutic factors. Next, the general structure and content for each session were presented. The structure consisted of seven well-defined individual sessions with an additional session, which could complement any of the former sessions to address the patient's issues in greater depth, if needed. This Dilemma-Focused Intervention manual aimed to improve the treatment outcome for depression by offering an intervention that could be combined with other general approaches. At its present level of definition, it allows for inclusion in controlled trials (eg, the current RCT combining group CBT with this intervention). Thus, this manual added to the existing resources in psychotherapeutic research and practice for treatment of depression.

  14. Varicella-zoster virus induces the formation of dynamic nuclear capsid aggregates

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lebrun, Marielle; Thelen, Nicolas; Thiry, Marc

    2014-04-15

    The first step of herpesviruses virion assembly occurs in the nucleus. However, the exact site where nucleocapsids are assembled, where the genome and the inner tegument are acquired, remains controversial. We created a recombinant VZV expressing ORF23 (homologous to HSV-1 VP26) fused to the eGFP and dually fluorescent viruses with a tegument protein additionally fused to a red tag (ORF9, ORF21 and ORF22 corresponding to HSV-1 UL49, UL37 and UL36). We identified nuclear dense structures containing the major capsid protein, the scaffold protein and maturing protease, as well as ORF21 and ORF22. Correlative microscopy demonstrated that the structures correspond tomore » capsid aggregates and time-lapse video imaging showed that they appear prior to the accumulation of cytoplasmic capsids, presumably undergoing the secondary egress, and are highly dynamic. Our observations suggest that these structures might represent a nuclear area important for capsid assembly and/or maturation before the budding at the inner nuclear membrane. - Highlights: • We created a recombinant VZV expressing the small capsid protein fused to the eGFP. • We identified nuclear dense structures containing capsid and procapsid proteins. • Correlative microscopy showed that the structures correspond to capsid aggregates. • Procapsids and partial capsids are found within the aggregates of WT and eGFP-23 VZV. • FRAP and FLIP experiments demonstrated that they are dynamic structures.« less

  15. Radiation Safety in Nuclear Medicine Procedures.

    PubMed

    Cho, Sang-Geon; Kim, Jahae; Song, Ho-Chun

    2017-03-01

    Since the nuclear disaster at the Fukushima Daiichi Nuclear Power Plant in 2011, radiation safety has become an important issue in nuclear medicine. Many structured guidelines or recommendations of various academic societies or international campaigns demonstrate important issues of radiation safety in nuclear medicine procedures. There are ongoing efforts to fulfill the basic principles of radiation protection in daily nuclear medicine practice. This article reviews important principles of radiation protection in nuclear medicine procedures. Useful references, important issues, future perspectives of the optimization of nuclear medicine procedures, and diagnostic reference level are also discussed.

  16. Exploring example models of cross-sector, sessional employment of pharmacists to improve medication management and pharmacy support in rural hospitals.

    PubMed

    Tan, Amy Cw; Emmerton, Lynne M; Hattingh, Laetitia; La Caze, Adam

    2015-01-01

    Many rural hospitals in Australia are not large enough to sustain employment of a full-time pharmacist, or are unable to recruit or retain a full-time pharmacist. The absence of a pharmacist may result in hospital nurses undertaking medication-related roles outside their scope of practice. A potential solution to address rural hospitals' medication management needs is contracted part-time ('sessional') employment of a local pharmacist external to the hospital ('cross-sector'). The aim of this study was to explore the roles and experiences of pharmacists in their provision of sessional services to rural hospitals with no on-site pharmacist and explore how these roles could potentially address shortfalls in medication management in rural hospitals. A qualitative study was conducted to explore models with pharmacists who had provided sessional services to a rural hospital. A semi-structured interview guide was informed by a literature review, preliminary research and stakeholder consultation. Participants were recruited via advertisement and personal contacts. Consenting pharmacists were interviewed between August 2012 and January 2013 via telephone or Skype for 40-55 minutes. Thirteen pharmacists with previous or ongoing hospital sessional contracts in rural communities across Australia and New Zealand participated. Most commonly, the pharmacists provided weekly services to rural hospitals. All believed the sessional model was a practical solution to increase hospital access to pharmacist-mediated support and to address medication management gaps. Roles perceived to promote quality use of medicines were inpatient consultation services, medicines information/education to hospital staff, assistance with accreditation matters and system reviews, and input into pharmaceutical distribution activities. This study is the first to explore the concept of sessional rural hospital employment undertaken by pharmacists in Australia and New Zealand. Insights from participants revealed that their sessional employment model increased access to pharmacist-mediated medication management support in rural hospitals. The contracting arrangements and scope of services may be evaluated and adapted in other rural hospitals.

  17. Introduction to session on materials and structures

    NASA Technical Reports Server (NTRS)

    Vosteen, L. F.

    1978-01-01

    A review was given of the development of composites for aircraft. Supporting base technology and the Aircraft Energy Efficiency Composites Program are included. Specific topics discussed include: (1) environmental effects on materials; (2) material quality and chemical characterization; (3) design and analysis methods; (4) structural durability; (5) impact sensitivity; (6) carbon fiber electrical effects; and (7) composite components.

  18. Rethinking the Effects of Classroom Activity Structure on the Engagement of Low-Achieving Students

    ERIC Educational Resources Information Center

    Kelly, Sean; Turner, Julianne

    2009-01-01

    Background/Context: A common perspective found in the literature on classroom activity structures hypothesizes that a whole-class mode of instruction is linked with increased problems of achievement motivation for low-achieving students. If whole-class methods of instruction (e.g., recitation-style question-and-answer sessions) are rich in…

  19. Molecular dynamics characterization of the conformational landscape of small peptides: A series of hands-on collaborative practical sessions for undergraduate students.

    PubMed

    Rodrigues, João P G L M; Melquiond, Adrien S J; Bonvin, Alexandre M J J

    2016-01-01

    Molecular modelling and simulations are nowadays an integral part of research in areas ranging from physics to chemistry to structural biology, as well as pharmaceutical drug design. This popularity is due to the development of high-performance hardware and of accurate and efficient molecular mechanics algorithms by the scientific community. These improvements are also benefitting scientific education. Molecular simulations, their underlying theory, and their applications are particularly difficult to grasp for undergraduate students. Having hands-on experience with the methods contributes to a better understanding and solidification of the concepts taught during the lectures. To this end, we have created a computer practical class, which has been running for the past five years, composed of several sessions where students characterize the conformational landscape of small peptides using molecular dynamics simulations in order to gain insights on their binding to protein receptors. In this report, we detail the ingredients and recipe necessary to establish and carry out this practical, as well as some of the questions posed to the students and their expected results. Further, we cite some examples of the students' written reports, provide statistics, and share their feedbacks on the structure and execution of the sessions. These sessions were implemented alongside a theoretical molecular modelling course but have also been used successfully as a standalone tutorial during specialized workshops. The availability of the material on our web page also facilitates this integration and dissemination and lends strength to the thesis of open-source science and education. © 2016 The International Union of Biochemistry and Molecular Biology.

  20. Role-play as an educational tool in medication communication skills: Students' perspectives.

    PubMed

    Lavanya, S H; Kalpana, L; Veena, R M; Bharath Kumar, V D

    2016-10-01

    Medication communication skills are vital aspects of patient care that may influence treatment outcomes. However, traditional pharmacology curriculum deals with imparting factual information, with little emphasis on patient communication. The current study aims to explore students' perceptions of role-play as an educational tool in acquiring communication skills and to ascertain the need of role-play for their future clinical practice. This questionnaire-based study was done in 2 nd professional MBBS students. A consolidated concept of six training cases, focusing on major communication issues related to medication prescription in pharmacology, were developed for peer-role-play sessions for 2 nd professional MBBS ( n = 122) students. Structured scripts with specific emphasis on prescription medication communication and checklists for feedback were developed. Prevalidated questionnaires measured the quantitative aspects of role-plays in relation to their relevance as teaching-learning tool, perceived benefits of sessions, and their importance for future use. Data analysis was performed using descriptive statistics. The role-play concept was well appreciated and considered an effective means for acquiring medication communication skills. The structured feedback by peers and faculty was well received by many. Over 90% of the students reported immense confidence in communicating therapy details, namely, drug name, purpose, mechanism, dosing details, and precautions. Majority reported a better retention of pharmacology concepts and preferred more such sessions. Most students consider peer-role-play as an indispensable tool to acquire effective communication skills regarding drug therapy. By virtue of providing experiential learning opportunities and its feasibility of implementation, role-play sessions justify inclusion in undergraduate medical curricula.

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