Sample records for numerical grading system

  1. Grading of direct laryngoscopy. A survey of current practice.

    PubMed

    Cohen, A M; Fleming, B G; Wace, J R

    1994-06-01

    One hundred and twenty anaesthetists (30 of each grade), from three separate regions, were interviewed as to how they recorded the appearance of laryngeal structures at direct laryngoscopy and about their knowledge of the commonly used numerical grading system. About two-thirds of anaesthetists surveyed (69.2%) used the numerical grading system, but of these, over half could not identify a 'grade 2' laryngoscopic appearance correctly. Of anaesthetists who did not use the numerical method, over half could not correctly state the difference between a 'grade 2' and a 'grade 3' laryngoscopic appearance. Over 40% of anaesthetists stated incorrectly that the grading should be made on the initial view, even when laryngeal pressure had been needed. Junior anaesthetists were more likely to use the numerical method of recording. The results show that there is unacceptable uncertainty and inaccuracy in the use of the numerical grading system by users as well as non-users, which makes the current routine clinical use of the numerical grading system unsatisfactory.

  2. The Changing Landscape of Grading Systems in US Higher Education

    ERIC Educational Resources Information Center

    Kleinman, Steven B.; Leidman, Mary Beth; Longcore, Andrew J.

    2018-01-01

    The following study explores the landscape of grading systems utilised in higher education, focusing on the frequency of different types of assessment scales (including Straight Letter, Plus/Minus, and other alternative policies). Although numerous studies have explored the relationship between university grading system and student behaviour,…

  3. Advantages and Disadvantages of Weighted Grading. Research Brief

    ERIC Educational Resources Information Center

    Walker, Karen

    2004-01-01

    What are the advantages and disadvantages of weighted grading? The primary purpose of weighted grading has been to encourage high school students to take more rigorous courses. This effort is then acknowledged by more weight being given to the grade for a specified class. There are numerous systems of weighted grading cited in the literature from…

  4. Non-Darcy Forchheimer flow of ferromagnetic second grade fluid

    NASA Astrophysics Data System (ADS)

    Hayat, T.; Ahmad, Salman; Khan, M. Ijaz; Alsaedi, A.

    This article discusses impacts of thermal radiation, viscous dissipation and magnetic dipole in flow of second grade fluid saturating porous medium. Porous medium is characterized by nonlinear Darcy-Forchheimer relation. Relevant nonlinear ordinary differential systems after using appropriate transformations are solved numerically. Shooting technique is implemented for the numerical treatment. Temperature, velocity, skin fraction and Nusselt number are analyzed.

  5. College Students' Categorical Perceptions of Grades: It's Simply "Good" vs. "Bad"

    ERIC Educational Resources Information Center

    Boatright-Horowitz, Su L.; Arruda, Chris

    2013-01-01

    College students' categorical perceptions of numeric and alphabetic grades were examined by assigning participants to one of four conditions: numeric grades alphabetic grades, numeric non-grades and alphabetic non-grades. They were then asked to give ratings for each possible grade or non-grade, using a 10-point scale. Factor analysis revealed…

  6. Cultural Influences on Number Preferences: Christmas and Grading Systems

    ERIC Educational Resources Information Center

    Stieger, Stefan; Krizan, Zlatan

    2013-01-01

    People consistently prefer numbers associated with themselves (e.g., birth dates) over other numbers. We argue that such number preferences are also shaped by cultural influences, such as customs regarding the day on which Christmas is celebrated and customs regarding ranking of numerals used in national school's grading system. Across 6 different…

  7. Monte Carlo study of holding forces for tank cars on grades

    DOT National Transportation Integrated Search

    2013-04-15

    This paper describes a numerical procedure to examine the holding forces needed to secure a cut of railroad tank cars staged on a grade during loading and unloading operations. Holding forces are created by applying emergency brake systems and blocki...

  8. An Analysis of Mobility in the North Carolina School Performance Grades

    ERIC Educational Resources Information Center

    Dietrich, Robert

    2017-01-01

    While numerous recent authors have studied the effects of school accountability systems on student test performance, there has been very little research with regards to school mobility with school performance grades in an A-F system. For the purpose of this study, mobility is defined as a school's ability to have an increase or decrease in their…

  9. Predictive Relation between Early Numerical Competencies and Mathematics Achievement in First Grade Portuguese Children.

    PubMed

    Marcelino, Lilia; de Sousa, Óscar; Lopes, António

    2017-01-01

    Early numerical competencies (ENC) (counting, number relations, and basic arithmetic operations) have a central position in the initial learning of mathematics, and their assessment is useful for predicting later mathematics achievement. Using a regression model, this study aims to analyze the correlational and predictive evidence between ENC and mathematics achievement in first grade Portuguese children ( n = 123). The children's ENC were examined at the point of school entry. Three criterion groups (low, moderate, and high ENC) were formed based on the results of the early numerical brief screener and mathematics achievement measured at the end of first grade. The following hypotheses were tested: children who started first grade with low numerical competencies remained low mathematics achievement at the end of first grade; and children who started with high numerical competencies, finished the first grade with high mathematics achievement. The results showed that ENC contributed to a significant amount of explained variance in mathematics achievement at the end of the first grade. Children with low numerical competencies performed lower than children with moderate and high numerical competencies. Findings suggest that ENC are meaningful for predicting first-grade mathematics difficulties.

  10. Predictive Relation between Early Numerical Competencies and Mathematics Achievement in First Grade Portuguese Children

    PubMed Central

    Marcelino, Lilia; de Sousa, Óscar; Lopes, António

    2017-01-01

    Early numerical competencies (ENC) (counting, number relations, and basic arithmetic operations) have a central position in the initial learning of mathematics, and their assessment is useful for predicting later mathematics achievement. Using a regression model, this study aims to analyze the correlational and predictive evidence between ENC and mathematics achievement in first grade Portuguese children (n = 123). The children’s ENC were examined at the point of school entry. Three criterion groups (low, moderate, and high ENC) were formed based on the results of the early numerical brief screener and mathematics achievement measured at the end of first grade. The following hypotheses were tested: children who started first grade with low numerical competencies remained low mathematics achievement at the end of first grade; and children who started with high numerical competencies, finished the first grade with high mathematics achievement. The results showed that ENC contributed to a significant amount of explained variance in mathematics achievement at the end of the first grade. Children with low numerical competencies performed lower than children with moderate and high numerical competencies. Findings suggest that ENC are meaningful for predicting first-grade mathematics difficulties. PMID:28713308

  11. Variation of student numerical and figural reasoning approaches by pattern generalization type, strategy use and grade level

    NASA Astrophysics Data System (ADS)

    El Mouhayar, Rabih; Jurdak, Murad

    2016-02-01

    This paper explored variation of student numerical and figural reasoning approaches across different pattern generalization types and across grade level. An instrument was designed for this purpose. The instrument was given to a sample of 1232 students from grades 4 to 11 from five schools in Lebanon. Analysis of data showed that the numerical reasoning approach seems to be more dominant than the figural reasoning approach for the near and far pattern generalization types but not for the immediate generalization type. The findings showed that for the recursive strategy, the numerical reasoning approach seems to be more dominant than the figural reasoning approach for each of the three pattern generalization types. However, the figural reasoning approach seems to be more dominant than the numerical reasoning approach for the functional strategy, for each generalization type. The findings also showed that the numerical reasoning was more dominant than the figural reasoning in lower grade levels (grades 4 and 5) for each generalization type. In contrast, the figural reasoning became more dominant than the numerical reasoning in the upper grade levels (grades 10 and 11).

  12. Maximization of the Thermoelectric Cooling of a Graded Peltier Device by Analytical Heat-Equation Resolution

    NASA Astrophysics Data System (ADS)

    Thiébaut, E.; Goupil, C.; Pesty, F.; D'Angelo, Y.; Guegan, G.; Lecoeur, P.

    2017-12-01

    Increasing the maximum cooling effect of a Peltier cooler can be achieved through material and device design. The use of inhomogeneous, functionally graded materials may be adopted in order to increase maximum cooling without improvement of the Z T (figure of merit); however, these systems are usually based on the assumption that the local optimization of the Z T is the suitable criterion to increase thermoelectric performance. We solve the heat equation in a graded material and perform both analytical and numerical analysis of a graded Peltier cooler. We find a local criterion that we use to assess the possible improvement of graded materials for thermoelectric cooling. A fair improvement of the cooling effect (up to 36%) is predicted for semiconductor materials, and the best graded system for cooling is described. The influence of the equation of state of the electronic gas of the material is discussed, and the difference in term of entropy production between the graded and the classical system is also described.

  13. General Math 10-12 [Instructional Objectives Exchange].

    ERIC Educational Resources Information Center

    California Univ., Los Angeles. Center for the Study of Evaluation.

    This collection of 123 objectives and related evaluation items is for general mathematics in grades 10 through 12. The content has been organized into nine major categories: sets; numbers, numerals, and numeration systems; operations and their properties; measurements; per cents; geometry; probability and statistics; logic; and applications and…

  14. Numerical predictors of arithmetic success in grades 1-6.

    PubMed

    Lyons, Ian M; Price, Gavin R; Vaessen, Anniek; Blomert, Leo; Ansari, Daniel

    2014-09-01

    Math relies on mastery and integration of a wide range of simpler numerical processes and concepts. Recent work has identified several numerical competencies that predict variation in math ability. We examined the unique relations between eight basic numerical skills and early arithmetic ability in a large sample (N = 1391) of children across grades 1-6. In grades 1-2, children's ability to judge the relative magnitude of numerical symbols was most predictive of early arithmetic skills. The unique contribution of children's ability to assess ordinality in numerical symbols steadily increased across grades, overtaking all other predictors by grade 6. We found no evidence that children's ability to judge the relative magnitude of approximate, nonsymbolic numbers was uniquely predictive of arithmetic ability at any grade. Overall, symbolic number processing was more predictive of arithmetic ability than nonsymbolic number processing, though the relative importance of symbolic number ability appears to shift from cardinal to ordinal processing. © 2014 John Wiley & Sons Ltd.

  15. Sources of Individual Differences in Emerging Competence With Numeration Understanding Versus Multidigit Calculation Skill

    PubMed Central

    Fuchs, Lynn S.; Geary, David C.; Fuchs, Douglas; Compton, Donald L.; Hamlett, Carol L.

    2014-01-01

    This study investigated contributions of general cognitive abilities and foundational mathematical competencies to numeration understanding (i.e., base-10 structure) versus multidigit calculation skill. Children (n = 394, M = 6.5 years) were assessed on general cognitive abilities and foundational numerical competencies at start of 1st grade; on the same numerical competencies, multidigit calculation skill, and numeration understanding at end of 2nd grade; and on multidigit calculation skill and numeration understanding at end of 3rd grade. Path-analytic mediation analysis revealed that general cognitive predictors exerted more direct and more substantial effects on numeration understanding than on multidigit calculations. Foundational mathematics competencies contributed to both outcomes, but largely via 2nd-grade mathematics achievement, and results suggest a mutually supportive role between numeration understanding and multidigit calculations. PMID:25284885

  16. Job Grading Standard for Brakeman and Conductor WG-6003.

    ERIC Educational Resources Information Center

    Civil Service Commission, Washington, DC. Bureau of Policies and Standards.

    The standard is used to grade the nonsupervisory work involved in coordinating (onsite) the movement, make up, or break up of trains, locomotives, and train cars. The work requires knowledge of the layout of a railroad track system; knowledge of and ability to follow numerous safety, signalling, switching, track use, train car, and train movement…

  17. A Longitudinal Study on Predictors of Early Calculation Development among Young Children At-Risk for Learning Difficulties

    PubMed Central

    Peng, Peng; Namkung, Jessica M.; Fuchs, Douglas; Fuchs, Lynn S.; Patton, Samuel; Yen, Loulee; Compton, Donald L.; Zhang, Wenjuan; Miller, Amanda; Hamlett, Carol

    2016-01-01

    The purpose of this study was to explore domain-general cognitive skills, domain-specific academic skills, and demographic characteristics that are associated with calculation development from first through third grade among young children with learning difficulties. Participants were 176 children identified with reading and mathematics difficulties at the beginning of first grade. Data were collected on working memory, language, nonverbal reasoning, processing speed, decoding, numerical competence, incoming calculations, socioeconomic status, and gender at the beginning of first grade and on calculation performance at 4 time points: the beginning of first grade, the end of first grade, the end of second grade, and the end of third grade. Latent growth modelling analysis showed that numerical competence, incoming calculation, processing speed, and decoding skills significantly explained the variance of calculation performance at the beginning of first grade. Numerical competence and processing speed significantly explained the variance of calculation performance at the end of third grade. However, numerical competence was the only significant predictor of calculation development from the beginning of first grade to the end of third grade. Implications of these findings for early calculation instructions among young at-risk children are discussed. PMID:27572520

  18. Elective Program Projects

    ERIC Educational Resources Information Center

    Estrada, Christelle

    1976-01-01

    Outlined is an interdisciplinary program in Ecology and Oceanography for grades six through eight. Numerous student projects are suggested in the outline and the course requirements and the project system are explained. (MA)

  19. Cranial Chordoma: A New Preoperative Grading System.

    PubMed

    Brito da Silva, Harley; Straus, David; Barber, Jason K; Rostomily, Robert C; Ferreira, Manuel; Sekhar, Laligam N

    2017-11-03

    Chordomas are rare but challenging neoplasms involving the skull base. A preoperative grading system will be useful to identify both areas for treatment and risk factors, and correlate to the degree of resection, complications, and recurrence. To propose a new grading system for cranial chordomas designed by the senior author. Its purpose is to enable comparison of different tumors with a similar pathology to clivus chordoma, and statistically correlate with postoperative outcomes. The numerical grading system included tumor size, site of the tumor, vascular encasement, intradural extension, brainstem invasion, and recurrence of the tumor either after surgery or radiotherapy with a range of 2 to 25 points; it was used in 42 patients with cranial chordoma. The grading system was correlated with number of operations for resection, degree of resection, number and type of complications, recurrence, and survival. We found 3 groups: low-risk 0 to 7 points, intermediate-risk 8 to 12 points, and high-risk ≥13 points in the grading system. The 3 groups were correlated with the following: extent of resection (partial, subtotal, or complete; P < .002); number of operative stages to achieve removal (P < .014); tumor recurrence (P = .03); postoperative Karnofsky Performance Status (P < .001); and with successful outcome (P = .005). The grading system itself correlated with the outcome (P = .005). The proposed chordoma grading system can help surgeons to predict the difficulty of the case and know which areas of the skull base will need attention to plan further therapy. © Congress of Neurological Surgeons 2017.

  20. A longitudinal study on predictors of early calculation development among young children at risk for learning difficulties.

    PubMed

    Peng, Peng; Namkung, Jessica M; Fuchs, Douglas; Fuchs, Lynn S; Patton, Samuel; Yen, Loulee; Compton, Donald L; Zhang, Wenjuan; Miller, Amanda; Hamlett, Carol

    2016-12-01

    The purpose of this study was to explore domain-general cognitive skills, domain-specific academic skills, and demographic characteristics that are associated with calculation development from first grade to third grade among young children with learning difficulties. Participants were 176 children identified with reading and mathematics difficulties at the beginning of first grade. Data were collected on working memory, language, nonverbal reasoning, processing speed, decoding, numerical competence, incoming calculations, socioeconomic status, and gender at the beginning of first grade and on calculation performance at four time points: the beginning of first grade, the end of first grade, the end of second grade, and the end of third grade. Latent growth modeling analysis showed that numerical competence, incoming calculation, processing speed, and decoding skills significantly explained the variance in calculation performance at the beginning of first grade. Numerical competence and processing speed significantly explained the variance in calculation performance at the end of third grade. However, numerical competence was the only significant predictor of calculation development from the beginning of first grade to the end of third grade. Implications of these findings for early calculation instructions among young at-risk children are discussed. Copyright © 2016 Elsevier Inc. All rights reserved.

  1. Development of preschool and academic skills in children born very preterm.

    PubMed

    Aarnoudse-Moens, Cornelieke Sandrine Hanan; Oosterlaan, Jaap; Duivenvoorden, Hugo Joseph; van Goudoever, Johannes Bernard; Weisglas-Kuperus, Nynke

    2011-01-01

    To examine performance in preschool and academic skills in very preterm (gestational age ≤ 30 weeks) and term-born comparison children aged 4 to 12 years. Very preterm children (n = 200; mean age, 8.2 ± 2.5 years) born between 1996 and 2004 were compared with 230 term-born children (mean age, 8.3 ± 2.3). The Dutch National Pupil Monitoring System was used to measure preschool numerical reasoning and early linguistics, and primary school simple and complex word reading, reading comprehension, spelling, and mathematics/arithmetic. With univariate analyses of variance, we assessed the effects of preterm birth on performance across grades and on grade retention. In preschool, very preterm children performed comparably with term-born children in early linguistics, but perform more poorly (0.7 standard deviation [SD]) in numerical reasoning skills. In primary school, very preterm children scored 0.3 SD lower in complex word reading and 0.6 SD lower in mathematics/arithmetic, but performed comparably with peers in reading comprehension and spelling. They had a higher grade repeat rate (25.5%), although grade repeat did not improve their academic skills. Very preterm children do well in early linguistics, reading comprehension, and spelling, but have clinically significant deficits in numerical reasoning skills and mathematics/arithmetic, which persist with time. Copyright © 2011 Mosby, Inc. All rights reserved.

  2. Design, Manufacturing and Characterization of Functionally Graded Flextensional Piezoelectric Actuators

    NASA Astrophysics Data System (ADS)

    Amigo, R. C. R.; Vatanabe, S. L.; Silva, E. C. N.

    2013-03-01

    Previous works have been shown several advantages in using Functionally Graded Materials (FGMs) for the performance of flextensional devices, such as reduction of stress concentrations and gains in reliability. In this work, the FGM concept is explored in the design of graded devices by using the Topology Optimization Method (TOM), in order to determine optimal topologies and gradations of the coupled structures of piezoactuators. The graded pieces are manufactured by using the Spark Plasma Sintering (SPS) technique and are bonded to piezoelectric ceramics. The graded actuators are then tested by using a modular vibrometer system for measuring output displacements, in order to validate the numerical simulations. The technological path developed here represents the initial step toward the manufacturing of an integral piezoelectric device, constituted by piezoelectric and non-piezoelectric materials without bonding layers.

  3. Antibody performance in ChIP-sequencing assays: From quality scores of public data sets to quantitative certification.

    PubMed

    Mendoza-Parra, Marco-Antonio; Saravaki, Vincent; Cholley, Pierre-Etienne; Blum, Matthias; Billoré, Benjamin; Gronemeyer, Hinrich

    2016-01-01

    We have established a certification system for antibodies to be used in chromatin immunoprecipitation assays coupled to massive parallel sequencing (ChIP-seq). This certification comprises a standardized ChIP procedure and the attribution of a numerical quality control indicator (QCi) to biological replicate experiments. The QCi computation is based on a universally applicable quality assessment that quantitates the global deviation of randomly sampled subsets of ChIP-seq dataset with the original genome-aligned sequence reads. Comparison with a QCi database for >28,000 ChIP-seq assays were used to attribute quality grades (ranging from 'AAA' to 'DDD') to a given dataset. In the present report we used the numerical QC system to assess the factors influencing the quality of ChIP-seq assays, including the nature of the target, the sequencing depth and the commercial source of the antibody.  We have used this approach specifically to certify mono and polyclonal antibodies obtained from Active Motif directed against the histone modification marks H3K4me3, H3K27ac and H3K9ac for ChIP-seq. The antibodies received the grades AAA to BBC ( www.ngs-qc.org). We propose to attribute such quantitative grading of all antibodies attributed with the label "ChIP-seq grade".

  4. Mediation Effects of Latent Numerical Abilities on the Associations between Domain General Competencies and Fraction Knowledge

    ERIC Educational Resources Information Center

    Ye, Ai; Hansen, Nicole; Resnick, Ilyse; Carrique, Jessica; Jordan, Nancy

    2016-01-01

    The purpose of the present study was to reveal the developmental pathway from third grade cognitive competencies to sixth grade conceptual and procedural fraction knowledge through the intervening whole numerical skills at fifth grade. The study used empirical data that come from 536 students in nine schools across two Delaware public school…

  5. Variation of Student Numerical and Figural Reasoning Approaches by Pattern Generalization Type, Strategy Use and Grade Level

    ERIC Educational Resources Information Center

    El Mouhayar, Rabih; Jurdak, Murad

    2016-01-01

    This paper explored variation of student numerical and figural reasoning approaches across different pattern generalization types and across grade level. An instrument was designed for this purpose. The instrument was given to a sample of 1232 students from grades 4 to 11 from five schools in Lebanon. Analysis of data showed that the numerical…

  6. A priori mesh grading for the numerical calculation of the head-related transfer functions

    PubMed Central

    Ziegelwanger, Harald; Kreuzer, Wolfgang; Majdak, Piotr

    2017-01-01

    Head-related transfer functions (HRTFs) describe the directional filtering of the incoming sound caused by the morphology of a listener’s head and pinnae. When an accurate model of a listener’s morphology exists, HRTFs can be calculated numerically with the boundary element method (BEM). However, the general recommendation to model the head and pinnae with at least six elements per wavelength renders the BEM as a time-consuming procedure when calculating HRTFs for the full audible frequency range. In this study, a mesh preprocessing algorithm is proposed, viz., a priori mesh grading, which reduces the computational costs in the HRTF calculation process significantly. The mesh grading algorithm deliberately violates the recommendation of at least six elements per wavelength in certain regions of the head and pinnae and varies the size of elements gradually according to an a priori defined grading function. The evaluation of the algorithm involved HRTFs calculated for various geometric objects including meshes of three human listeners and various grading functions. The numerical accuracy and the predicted sound-localization performance of calculated HRTFs were analyzed. A-priori mesh grading appeared to be suitable for the numerical calculation of HRTFs in the full audible frequency range and outperformed uniform meshes in terms of numerical errors, perception based predictions of sound-localization performance, and computational costs. PMID:28239186

  7. PHYSICAL AND NUMERICAL MODELING OF ASD EXHAUST DISPERSION AROUND HOUSES

    EPA Science Inventory

    The report discusses the use of a wind tunnel to physically model the dispersion of exhaust plumes from active soil depressurization (ASD) radon mitigation systems in houses. he testing studied the effects of exhaust location (grade level vs. above the eave), as house height, roo...

  8. Morphodynamics modelling of bars in channels with graded sediment and sediment supply variation with the Telemac-Mascaret System

    NASA Astrophysics Data System (ADS)

    Cordier, Florian; Tassi, Pablo; Claude, Nicolas; Crosato, Alessandra; Rodrigues, Stéphane; Pham van Bang, Damien

    2017-04-01

    Numerical modelling of graded sediment transport in rivers remains a challenge [Siviglia and Crosato, 2016] and only few studies have considered the non-uniform distribution of sediment, although sediment grading is an inherent characteristic of natural rivers. The present work aims at revisiting the morphodynamics module of the Telemac-Mascaret modelling system and to integrate the latest developments to model the effects of non-uniform sediment on i) the sediment transport capacity estimated at the interface between the flow and the riverbed and on ii) the vertical sorting of sediment deposits in response to sediment supply changes. The implementation of these two processes has a key role on the modelling of bar dynamics in aggrading/degrading channels [Blom, 2008]. Numerical modelling of graded sediment transport remains a challenge due to the difficulty to reproduce the non-linear interactions between grains of different shape and size. Application of classical bedload equations usually fails in reproducing relevant transport rates [Recking, 2010 and references therein]. In this work, the graded sediment transport model of Wilcock and Crowe [2003] and the active layer concept of Hirano [1971] for the formulation of the exchange layer are implemented. The ability to reproduce the formation and evolution of graded-sediment bars is assessed on the basis of laboratory experiences from the literature. References: Blom, A., Ribberink, J. S., and Parker, G. 2008. Vertical sorting and the morphodynamics of bed form-dominated rivers: A sorting evolution model. Journal of Geophysical Research: Earth Surface, 113(F1). Lauer, J. W., Viparelli, E., and Piégay, H. 2016. Morphodynamics and sediment tracers in 1-d (mast-1d): 1-d sediment transport that includes exchange with an off-channel sediment reservoir. Advances in Water Resources. Recking, A. 2010. A comparison between flume and field bed load transport data and consequences for surface-based bed load transport prediction. Water Resources Research, 46(3). W03518. Siviglia, A. and Crosato, A. 2016. Numerical modelling of river morphodynamics: latest developments and remaining challenges. Advances in Water Resources, 90:1-9. Wilcock, P. R. and Crowe, J. C. 2003. Surface-based transport model for mixed-size sediment. Journal of Hydraulic Engineering, 129(2):120-128.

  9. When the Elephant "Is" the Room

    ERIC Educational Resources Information Center

    Butler, Lawrence

    2012-01-01

    For several years now, many have been agonizing over the sorry state of American higher education--indeed, of the entire educational system. Numerous causes have been cited for this state of affairs from poor high school preparation to inadequate governmental financial aid policies to postsecondary grade inflation. The most recent culprit "du…

  10. Collection of low-grade waste heat for enhanced energy harvesting

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dede, Ercan M., E-mail: eric.dede@tema.toyota.com; Schmalenberg, Paul; Wang, Chi-Ming

    Enhanced energy harvesting through the collection of low-grade waste heat is experimentally demonstrated. A structural optimization technique is exploited in the design of a thermal-composite substrate to guide and gather the heat emanating from multiple sources to a predetermined location. A thermoelectric generator is then applied at the selected focusing region to convert the resulting low-grade waste heat to electrical power. The thermal characteristics of the device are experimentally verified by direct temperature measurements of the system and numerically validated via heat conduction simulations. Electrical performance under natural and forced convection is measured, and in both cases, the device withmore » optimized heat flow control plus energy harvesting demonstrates increased power generation when compared with a baseline waste heat recovery system. Electronics applications include energy scavenging for autonomously powered sensor networks or self-actuated devices.« less

  11. Proposal of a Video-recording System for the Assessment of Bell's Palsy: Methodology and Preliminary Results.

    PubMed

    Monini, Simonetta; Marinozzi, Franco; Atturo, Francesca; Bini, Fabiano; Marchelletta, Silvia; Barbara, Maurizio

    2017-09-01

    To propose a new objective video-recording procedure to assess and monitor over time the severity of facial nerve palsy. No objective methods for facial palsy (FP) assessment are universally accepted. The face of subjects presenting with different degrees of facial nerve deficit, as measured by the House-Brackmann (HB) grading system, was videotaped after positioning, at specific points, 10 gray circular markers made of a retroreflective material. Video-recording included the resting position and six ordered facial movements. Editing and data elaboration was performed using a software instructed to assess marker distances. From the differences of the marker distances between the two sides was then extracted a score. The higher the FP degree, the higher the score registered during each movement. The statistical significance differed during the various movements between the different FP degrees, being uniform when closing the eyes gently; whereas when wrinkling the nose, there was no difference between the HB grade III and IV groups and, when smiling, no difference was evidenced between the HB grade IV and V groups.The global range index, which represents the overall degree of FP, was between 6.2 and 7.9 in the normal subjects (HB grade I); between 10.6 and 18.91 in HB grade II; between 22.19 and 33.06 in HB grade III; between 38.61 and 49.75 in HB grade IV; and between 50.97 and 66.88 in HB grade V. The proposed objective methodology could provide numerical data that correspond to the different degrees of FP, as assessed by the subjective HB grading system. These data can in addition be used singularly to score selected areas of the paralyzed face when recovery occurs with a different timing in the different face regions.

  12. Grading smart sensors: Performance assessment and ranking using familiar scores like A+ to D-

    NASA Astrophysics Data System (ADS)

    Kessel, Ronald T.

    2005-03-01

    Starting with the supposition that the product of smart sensors - whether autonomous, networked, or fused - is in all cases information, it is shown here using information theory how a metric Q, ranging between 0 and 100%, can be derived to assess the quality of the information provided. The analogy with student grades is immediately evident and elaborated. As with student grades, numerical percentages suggest more precision than can be justified, so a conversion to letter grades A+ to D- is desirable. Owing to the close analogy with familiar academic grades, moreover, the new grade is a measure of effectiveness (MOE) that commanders and decision makers should immediately appreciate and find quite natural, even if they do not care to follow the methodology behind the performance test, as they focus on higher-level strategic matters of sensor deployment or procurement. The metric is illustrated by translating three specialist performance tests - the Receiver Operating Characteristic (ROC) curve, the Constant False Alarm Rate (CFAR) approach, and confusion matrices - into letter grades for use then by strategists. Actual military and security systems are included among the examples.

  13. Grading as a Sadomasochistic Activity or an Erotic Benevolent Activity?

    ERIC Educational Resources Information Center

    Tjarks, Larry D.

    Numerous research studies have been conducted concerning the negative aspects of grading: the low correlations between academic success (high grades) and later vocational or professional success, possible sadomasochistic motives of teachers in awarding grades, and grade assignment resulting from the teacher's sense of duty or responsibility to…

  14. Acoustic wave propagation in continuous functionally graded plates: an extension of the Legendre polynomial approach.

    PubMed

    Lefebvre, J E; Zhang, V; Gazalet, J; Gryba, T; Sadaune, V

    2001-09-01

    The propagation of guided waves in continuous functionally graded plates is studied by using Legendre polynomials. Dispersion curves, and power and field profiles are easily obtained. Our computer program is validated by comparing our results against other calculations from the literature. Numerical results are also given for a graded semiconductor plate. It is felt that the present method could be of quite practical interest in waveguiding engineering, non-destructive testing of functionally graded materials (FGMs) to identify the best inspection strategies, or by means of a numerical inversion algorithm to determine through-thickness gradients in material parameters.

  15. Theory of biaxial graded-index optical fiber. M.S. Thesis

    NASA Technical Reports Server (NTRS)

    Kawalko, Stephen F.

    1990-01-01

    A biaxial graded-index fiber with a homogeneous cladding is studied. Two methods, wave equation and matrix differential equation, of formulating the problem and their respective solutions are discussed. For the wave equation formulation of the problem it is shown that for the case of a diagonal permittivity tensor the longitudinal electric and magnetic fields satisfy a pair of coupled second-order differential equations. Also, a generalized dispersion relation is derived in terms of the solutions for the longitudinal electric and magnetic fields. For the case of a step-index fiber, either isotropic or uniaxial, these differential equations can be solved exactly in terms of Bessel functions. For the cases of an istropic graded-index and a uniaxial graded-index fiber, a solution using the Wentzel, Krammers and Brillouin (WKB) approximation technique is shown. Results for some particular permittivity profiles are presented. Also the WKB solutions is compared with the vector solution found by Kurtz and Streifer. For the matrix formulation it is shown that the tangential components of the electric and magnetic fields satisfy a system of four first-order differential equations which can be conveniently written in matrix form. For the special case of meridional modes, the system of equations splits into two systems of two equations. A general iterative technique, asymptotic partitioning of systems of equations, for solving systems of differential equations is presented. As a simple example, Bessel's differential equation is written in matrix form and is solved using this asymptotic technique. Low order solutions for particular examples of a biaxial and uniaxial graded-index fiber are presented. Finally numerical results obtained using the asymptotic technique are presented for particular examples of isotropic and uniaxial step-index fibers and isotropic, uniaxial and biaxial graded-index fibers.

  16. Computational analysis of heat transfer, thermal stress and dislocation density during resistively Czochralski growth of germanium single crystal

    NASA Astrophysics Data System (ADS)

    Tavakoli, Mohammad Hossein; Renani, Elahe Kabiri; Honarmandnia, Mohtaram; Ezheiyan, Mahdi

    2018-02-01

    In this paper, a set of numerical simulations of fluid flow, temperature gradient, thermal stress and dislocation density for a Czochralski setup used to grow IR optical-grade Ge single crystal have been done for different stages of the growth process. A two-dimensional steady state finite element method has been applied for all calculations. The obtained numerical results reveal that the thermal field, thermal stress and dislocation structure are mainly dependent on the crystal height, heat radiation and gas flow in the growth system.

  17. Numerical simulation of the induction heating of hybrid semi-finished materials into the semi-solid state

    NASA Astrophysics Data System (ADS)

    Seyboldt, Christoph; Liewald, Mathias

    2017-10-01

    Current research activities at the Institute for Metal Forming Technology (IFU) of the University of Stuttgart are focusing on the manufacturing of hybrid components using semi-solid forming strategies. As part of the research project "Hybrid interaction during and after thixoforging of multi-material systems", which is founded by the German Research Foundation (DFG), a thixoforging process for producing hybrid components with cohesive metal-to-metal connections is developed. In this context, this paper deals with the numerical simulation of the inductive heating process of hybrid semi-finished materials, consisting of two different aluminium alloys. By reason of the skin effect that leads to inhomogeneous temperature distributions during inductive heating processes, the aluminium alloy with the higher melting point is thereby assembled in the outer side and the alloy with the lower melting point is assembled in the core of the semi-finished material. In this way, the graded heat distribution can be adapted to the used materialś flow properties that are heavily heat dependent. Without this graded heat distribution a proper forming process in the semi-solid state will not be possible. For numerically modelling the inductive heating system of the institute, a coupling of the magnetostatic and the thermal solver was realized by using Ansys Workbench. While the electromagnetic field and its associated heat production rate were solved in a frequency domain, the temperature development was solved in the time based domain. The numerical analysis showed that because of the high thermal conductivity of the aluminium, which leads to a rapid temperature equalization in the semi-finished material, the heating process has to be fast and with a high frequency for produce most heat in the outer region of the material. Finally, the obtained numerical results were validated with experimental heating tests.

  18. Number line estimation and mental addition: examining the potential roles of language and education.

    PubMed

    Laski, Elida V; Yu, Qingyi

    2014-01-01

    This study investigated the relative importance of language and education to the development of numerical knowledge. Consistent with previous research suggesting that counting systems that transparently reflect the base-10 system facilitate an understanding of numerical concepts, Chinese and Chinese American kindergartners' and second graders' number line estimation (0-100 and 0-1000) was 1 to 2 years more advanced than that of American children tested in previous studies. However, Chinese children performed better than their Chinese American peers, who were fluent in Chinese but had been educated in America, at kindergarten on 0-100 number lines, at second grade on 0-1000 number lines, and at both time points on complex addition problems. Overall, the pattern of findings suggests that educational approach may have a greater influence on numerical development than the linguistic structure of the counting system. The findings also demonstrate that, despite generating accurate estimates of numerical magnitude on 0-100 number lines earlier, it still takes Chinese children approximately 2 years to demonstrate accurate estimates on 0-1000 number lines, which raises questions about how to promote the mapping of knowledge across numerical scales. Copyright © 2013 Elsevier Inc. All rights reserved.

  19. Development of numerical processing in children with typical and dyscalculic arithmetic skills—a longitudinal study

    PubMed Central

    Landerl, Karin

    2013-01-01

    Numerical processing has been demonstrated to be closely associated with arithmetic skills, however, our knowledge on the development of the relevant cognitive mechanisms is limited. The present longitudinal study investigated the developmental trajectories of numerical processing in 42 children with age-adequate arithmetic development and 41 children with dyscalculia over a 2-year period from beginning of Grade 2, when children were 7; 6 years old, to beginning of Grade 4. A battery of numerical processing tasks (dot enumeration, non-symbolic and symbolic comparison of one- and two-digit numbers, physical comparison, number line estimation) was given five times during the study (beginning and middle of each school year). Efficiency of numerical processing was a very good indicator of development in numerical processing while within-task effects remained largely constant and showed low long-term stability before middle of Grade 3. Children with dyscalculia showed less efficient numerical processing reflected in specifically prolonged response times. Importantly, they showed consistently larger slopes for dot enumeration in the subitizing range, an untypically large compatibility effect when processing two-digit numbers, and they were consistently less accurate in placing numbers on a number line. Thus, we were able to identify parameters that can be used in future research to characterize numerical processing in typical and dyscalculic development. These parameters can also be helpful for identification of children who struggle in their numerical development. PMID:23898310

  20. When Discourses Collide: An Ethnography of Migrant Children at Home and in School. Rethinking Childhood, Volume 11.

    ERIC Educational Resources Information Center

    Lopez, Marianne Exum

    This critical ethnographic study examines the discourse systems experienced by three migrant fifth-grade boys during an apple harvest season in south-central Pennsylvania. Numerous examples reveal the discourse collisions facing these boys, whose home language and culture did not reflect the mainstream, and how dominant mainstream discourses…

  1. Ability-Based Criteria and the Lower Class Student: The De Facto Screw.

    ERIC Educational Resources Information Center

    Amato, Josephine; Backman, Carl B.

    Social class discrimination in the schooling process is less a product of teachers' attitudes than of the systems by which schools group students. Although class bias has been demonstrated in grading practices and other key decision points, numerous studies have shown that teachers are less to blame for inequitable learning situations than…

  2. Development of a Top-View Numeric Coding Teaching-Learning Trajectory within an Elementary Grades 3-D Visualization Design Research Project

    ERIC Educational Resources Information Center

    Sack, Jacqueline J.

    2013-01-01

    This article explicates the development of top-view numeric coding of 3-D cube structures within a design research project focused on 3-D visualization skills for elementary grades children. It describes children's conceptual development of 3-D cube structures using concrete models, conventional 2-D pictures and abstract top-view numeric…

  3. A cylindrical optical black hole using graded index photonic crystals

    NASA Astrophysics Data System (ADS)

    Wang, Hung-Wen; Chen, Lien-Wen

    2011-05-01

    The electromagnetic wave propagation of a two-dimensional optical black hole with graded index photonic crystals for transverse magnetic modes is studied. The implementation of the proposed system is validated in the metamaterial regime. The finite element method is employed in order to confirm the optical properties of the designed device. Numerical simulations show that the light incident on the device is bent toward the central area and absorbed by the inner core. As a result, the artificial optical black hole can effectively absorb the incident waves from all directions. The structure is composed of two kinds of real isotropic materials, which eases the experimental fabrication.

  4. Components of Students' Grade Expectations for Public Speaking Assignments

    ERIC Educational Resources Information Center

    Larseingue, Matt; Sawyer, Chris R.; Finn, Amber N.

    2012-01-01

    Although previous research has linked students' expected grades to numerous pedagogical variables, this factor has been all but ignored by instructional communication scholars. In the present study, 315 undergraduates were presented with grading scenarios representing differing combinations of course rigor, teacher immediacy, and student…

  5. Dispersion relations of elastic waves in one-dimensional piezoelectric/piezomagnetic phononic crystal with functionally graded interlayers.

    PubMed

    Guo, Xiao; Wei, Peijun; Lan, Man; Li, Li

    2016-08-01

    The effects of functionally graded interlayers on dispersion relations of elastic waves in a one-dimensional piezoelectric/piezomagnetic phononic crystal are studied in this paper. First, the state transfer equation of the functionally graded interlayer is derived from the motion equation by the reduction of order (from second order to first order). The transfer matrix of the functionally graded interlayer is obtained by solving the state transfer equation with the spatial-varying coefficient. Based on the transfer matrixes of the piezoelectric slab, the piezomagnetic slab and the functionally graded interlayers, the total transfer matrix of a single cell is obtained. Further, the Bloch theorem is used to obtain the resultant dispersion equations of in-plane and anti-plane Bloch waves. The dispersion equations are solved numerically and the numerical results are shown graphically. Five kinds of profiles of functionally graded interlayers between a piezoelectric slab and a piezomagnetic slab are considered. It is shown that the functionally graded interlayers have evident influences on the dispersion curves and the band gaps. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Point by Point: Adding up Motivation

    ERIC Educational Resources Information Center

    Marchionda, Denise

    2010-01-01

    Students often view their course grades as a mysterious equation of teacher-given grades, teacher-given grace, and some other ethereal components based on luck. However, giving students the power to earn points based on numerous daily/weekly assignments and attendance makes the grading process objective and personal, freeing the instructor to…

  7. CSMP Mathematics for the Upper Primary Grades Part II, Teacher's Guide [and] Worksheets. General Introduction. The World of Numbers. Final Experimental Version.

    ERIC Educational Resources Information Center

    Heidema, Clare; Schweitzer, Janis

    This guide represents the final experimental version of a pilot project conducted in the United States between 1973 and 1976. The ideas and manner of presentation are based on the works of Georges and Frederique Papy. They are recognized as having introduced colored arrow drawings ("papygrams") and models of our numeration system (the…

  8. CSMP Mathematics for the Upper Primary Grades Part I, Teacher's Guide [and] Worksheets. General Introduction. The World of Numbers. Final Experimental Version.

    ERIC Educational Resources Information Center

    Heidema, Clare; Schweitzer, Janis

    This guide represents the final experimental version of a pilot project conducted in the United States between 1973 and 1976. The ideas and manner of presentation are based on the works of Georges and Frederique Papy. They are recognized as having introduced colored arrow drawings ("papygrams") and models of our numeration system (the…

  9. Symbolic magnitude processing in elementary school children: A group administered paper-and-pencil measure (SYMP Test).

    PubMed

    Brankaer, Carmen; Ghesquière, Pol; De Smedt, Bert

    2017-08-01

    The ability to compare symbolic numerical magnitudes correlates with children's concurrent and future mathematics achievement. We developed and evaluated a quick timed paper-and-pencil measure that can easily be used, for example in large-scale research, in which children have to cross out the numerically larger of two Arabic one- and two-digit numbers (SYMP Test). We investigated performance on this test in 1,588 primary school children (Grades 1-6) and examined in each grade its associations with mathematics achievement. The SYMP Test had satisfactory test-retest reliability. The SYMP Test showed significant and stable correlations with mathematics achievement for both one-digit and two-digit comparison, across all grades. This replicates the previously observed association between symbolic numerical magnitude processing and mathematics achievement, but extends it by showing that the association is observed in all grades in primary education and occurs for single- as well as multi-digit processing. Children with mathematical learning difficulties performed significantly lower on one-digit comparison and two-digit comparison in all grades. This all suggests satisfactory construct and criterion-related validity of the SYMP Test, which can be used in research, when performing large-scale (intervention) studies, and by practitioners, as screening measure to identify children at risk for mathematical difficulties or dyscalculia.

  10. Preschool predictors of mathematics in first grade children with autism spectrum disorder.

    PubMed

    Titeca, Daisy; Roeyers, Herbert; Josephy, Haeike; Ceulemans, Annelies; Desoete, Annemie

    2014-11-01

    Up till now, research evidence on the mathematical abilities of children with autism spectrum disorder (ASD) has been scarce and provided mixed results. The current study examined the predictive value of five early numerical competencies for four domains of mathematics in first grade. Thirty-three high-functioning children with ASD were followed up from preschool to first grade and compared with 54 typically developing children, as well as with normed samples in first grade. Five early numerical competencies were tested in preschool (5-6 years): verbal subitizing, counting, magnitude comparison, estimation, and arithmetic operations. Four domains of mathematics were used as outcome variables in first grade (6-7 years): procedural calculation, number fact retrieval, word/language problems, and time-related competences. Children with ASD showed similar early numerical competencies at preschool age as typically developing children. Moreover, they scored average on number fact retrieval and time-related competences and higher on procedural calculation and word/language problems compared to the normed population in first grade. When predicting first grade mathematics performance in children with ASD, both verbal subitizing and counting seemed to be important to evaluate at preschool age. Verbal subitizing had a higher predictive value in children with ASD than in typically developing children. Whereas verbal subitizing was predictive for procedural calculation, number fact retrieval, and word/language problems, counting was predictive for procedural calculation and, to a lesser extent, number fact retrieval. Implications and directions for future research are discussed. Copyright © 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.

  11. Systematic analysis underlying the quality of the scientific evidence and conflicts of interest in gastroenterology practice guidelines.

    PubMed

    Feuerstein, Joseph D; Gifford, Anne E; Akbari, Mona; Goldman, Jonathan; Leffler, Daniel A; Sheth, Sunil G; Cheifetz, Adam S

    2013-11-01

    The practice guidelines published by the American Gastroenterological Association (AGA) and the American College of Gastroenterology (ACG) are used to establish standards of care and improve patient outcomes. We examined the guidelines for quality of evidence, methods of grading evidence, and conflicts of interest (COIs). All 81 (AGA and ACG) guidelines available online on 26 July 2012 were reviewed for the presence of grading of evidence and COIs. In total, 570 recommendations were evaluated for level of evidence and methods used to grade the evidence. The data were evaluated in aggregate and by society. Only 31% (n=25) of the guidelines graded the levels of evidence. A total of 12 systems were used to grade the quality of evidence in these 25 guidelines. Of the 570 recommendations reviewed, only 29% (n=165) were supported by the highest quality of evidence, level A; 37% (n=210) level B, 29% (n=165) level C, and 5% (n=30) level D. Since 2007, 87% (n=13/15) of the ACG guidelines graded the evidence compared with only 33% of the AGA guidelines (n=4/12). Furthermore, 70% (n=57/81) of the guidelines failed to disclose any information regarding COIs. Of the 24 articles commenting on COIs, 67% reported COIs. Although the majority of the gastroenterology guidelines fail to grade the quality of evidence, more recent ACG guidelines grade majority of their recommendations. When the evidence is graded, most of the supporting evidence is based on lower-quality evidence. In addition, most of the guidelines fail to comment on COIs, and when disclosed, numerous COIs were present. This study highlights the critical need to revise the guideline development process. Future guidelines should clearly state the quality of evidence for their recommendations, utilize a standard grading system, and be transparent regarding all COIs.

  12. Prediction of Petermann I and II Spot Sizes for Single-mode Dispersion-shifted and Dispersion-flattened Fibers by a Simple Technique

    NASA Astrophysics Data System (ADS)

    Kamila, Kiranmay; Panda, Anup Kumar; Gangopadhyay, Sankar

    2013-09-01

    Employing the series expression for the fundamental modal field of dispersion-shifted trapezoidal and dispersion-flattened graded and step W fibers, we present simple but accurate analytical expressions for Petermann I and II spot sizes of such kind of fibers. Choosing some typical dispersion-shifted trapezoidal and dispersion-flattened graded and step W fibers as examples, we show that our estimations match excellently with the exact numerical results. The evaluation of the concerned propagation parameters by our formalism needs very little computations. This accurate but simple formalism will benefit the system engineers working in the field of all optical technology.

  13. A hybrid neural networks-fuzzy logic-genetic algorithm for grade estimation

    NASA Astrophysics Data System (ADS)

    Tahmasebi, Pejman; Hezarkhani, Ardeshir

    2012-05-01

    The grade estimation is a quite important and money/time-consuming stage in a mine project, which is considered as a challenge for the geologists and mining engineers due to the structural complexities in mineral ore deposits. To overcome this problem, several artificial intelligence techniques such as Artificial Neural Networks (ANN) and Fuzzy Logic (FL) have recently been employed with various architectures and properties. However, due to the constraints of both methods, they yield the desired results only under the specific circumstances. As an example, one major problem in FL is the difficulty of constructing the membership functions (MFs).Other problems such as architecture and local minima could also be located in ANN designing. Therefore, a new methodology is presented in this paper for grade estimation. This method which is based on ANN and FL is called "Coactive Neuro-Fuzzy Inference System" (CANFIS) which combines two approaches, ANN and FL. The combination of these two artificial intelligence approaches is achieved via the verbal and numerical power of intelligent systems. To improve the performance of this system, a Genetic Algorithm (GA) - as a well-known technique to solve the complex optimization problems - is also employed to optimize the network parameters including learning rate, momentum of the network and the number of MFs for each input. A comparison of these techniques (ANN, Adaptive Neuro-Fuzzy Inference System or ANFIS) with this new method (CANFIS-GA) is also carried out through a case study in Sungun copper deposit, located in East-Azerbaijan, Iran. The results show that CANFIS-GA could be a faster and more accurate alternative to the existing time-consuming methodologies for ore grade estimation and that is, therefore, suggested to be applied for grade estimation in similar problems.

  14. Buckling of a stiff thin film on an elastic graded compliant substrate.

    PubMed

    Chen, Zhou; Chen, Weiqiu; Song, Jizhou

    2017-12-01

    The buckling of a stiff film on a compliant substrate has attracted much attention due to its wide applications such as thin-film metrology, surface patterning and stretchable electronics. An analytical model is established for the buckling of a stiff thin film on a semi-infinite elastic graded compliant substrate subjected to in-plane compression. The critical compressive strain and buckling wavelength for the sinusoidal mode are obtained analytically for the case with the substrate modulus decaying exponentially. The rigorous finite element analysis (FEA) is performed to validate the analytical model and investigate the postbuckling behaviour of the system. The critical buckling strain for the period-doubling mode is obtained numerically. The influences of various material parameters on the results are investigated. These results are helpful to provide physical insights on the buckling of elastic graded substrate-supported thin film.

  15. Buckling of a stiff thin film on an elastic graded compliant substrate

    NASA Astrophysics Data System (ADS)

    Chen, Zhou; Chen, Weiqiu; Song, Jizhou

    2017-12-01

    The buckling of a stiff film on a compliant substrate has attracted much attention due to its wide applications such as thin-film metrology, surface patterning and stretchable electronics. An analytical model is established for the buckling of a stiff thin film on a semi-infinite elastic graded compliant substrate subjected to in-plane compression. The critical compressive strain and buckling wavelength for the sinusoidal mode are obtained analytically for the case with the substrate modulus decaying exponentially. The rigorous finite element analysis (FEA) is performed to validate the analytical model and investigate the postbuckling behaviour of the system. The critical buckling strain for the period-doubling mode is obtained numerically. The influences of various material parameters on the results are investigated. These results are helpful to provide physical insights on the buckling of elastic graded substrate-supported thin film.

  16. Active vibration control of functionally graded beams with piezoelectric layers based on higher order shear deformation theory

    NASA Astrophysics Data System (ADS)

    Bendine, K.; Boukhoulda, F. B.; Nouari, M.; Satla, Z.

    2016-12-01

    This paper reports on a study of active vibration control of functionally graded beams with upper and lower surface-bonded piezoelectric layers. The model is based on higher-order shear deformation theory and implemented using the finite element method (FEM). The proprieties of the functionally graded beam (FGB) are graded along the thickness direction. The piezoelectric actuator provides a damping effect on the FGB by means of a velocity feedback control algorithm. A Matlab program has been developed for the FGB model and compared with ANSYS APDL. Using Newmark's method numerical solutions are obtained for the dynamic equations of FGB with piezoelectric layers. Numerical results show the effects of the constituent volume fraction and the influence the feedback control gain on the frequency and dynamic response of FGBs.

  17. 8. VIEW OF A THIRD CULVERT ALONG THE RAILROAD GRADE, ...

    Library of Congress Historic Buildings Survey, Historic Engineering Record, Historic Landscapes Survey

    8. VIEW OF A THIRD CULVERT ALONG THE RAILROAD GRADE, LOOKING WEST. THERE ARE NUMEROUS CULVERTS IN THE GRADE ACCORDING TO THE 1933 AS-BUILT PLANS, BUT NO OTHERS WERE OBVIOUS IN A DRIVE-THROUGH OF THE AREA. - Great Northern Railroad Bed, From Big Sandy to Verona, Fort Benton, Chouteau County, MT

  18. Developmental Foundations of Children's Fraction Magnitude Knowledge.

    PubMed

    Mou, Yi; Li, Yaoran; Hoard, Mary K; Nugent, Lara D; Chu, Felicia W; Rouder, Jeffrey N; Geary, David C

    2016-01-01

    The conceptual insight that fractions represent magnitudes is a critical yet daunting step in children's mathematical development, and the knowledge of fraction magnitudes influences children's later mathematics learning including algebra. In this study, longitudinal data were analyzed to identify the mathematical knowledge and domain-general competencies that predicted 8 th and 9 th graders' (n=122) knowledge of fraction magnitudes and its cross-grade gains. Performance on the fraction magnitude measures predicted 9 th grade algebra achievement. Understanding and fluently identifying the numerator-denominator relation in 7 th grade emerged as the key predictor of later fraction magnitudes knowledge in both 8 th and 9 th grades. Competence at using fraction procedures, knowledge of whole number magnitudes, and the central executive contributed to 9 th but not 8 th graders' fraction magnitude knowledge, and knowledge of whole number magnitude contributed to cross-grade gains. The key results suggest fluent processing of numerator-denominator relations presages students' understanding of fractions as magnitudes and that the integration of whole number and fraction magnitudes occurs gradually.

  19. Symbolic Numerical Magnitude Processing Is as Important to Arithmetic as Phonological Awareness Is to Reading

    PubMed Central

    Vanbinst, Kiran; Ansari, Daniel; Ghesquière, Pol; De Smedt, Bert

    2016-01-01

    In this article, we tested, using a 1-year longitudinal design, whether symbolic numerical magnitude processing or children’s numerical representation of Arabic digits, is as important to arithmetic as phonological awareness is to reading. Children completed measures of symbolic comparison, phonological awareness, arithmetic, reading at the start of third grade and the latter two were retested at the start of fourth grade. Cross-sectional and longitudinal correlations indicated that symbolic comparison was a powerful domain-specific predictor of arithmetic and that phonological awareness was a unique predictor of reading. Crucially, the strength of these independent associations was not significantly different. This indicates that symbolic numerical magnitude processing is as important to arithmetic development as phonological awareness is to reading and suggests that symbolic numerical magnitude processing is a good candidate for screening children at risk for developing mathematical difficulties. PMID:26942935

  20. Maternal Support of Children's Early Numerical Concept Learning Predicts Preschool and First-Grade Math Achievement.

    PubMed

    Casey, Beth M; Lombardi, Caitlin M; Thomson, Dana; Nguyen, Hoa Nha; Paz, Melissa; Theriault, Cote A; Dearing, Eric

    2018-01-01

    The primary goal in this study was to examine maternal support of numerical concepts at 36 months as predictors of math achievement at 4½ and 6-7 years. Observational measures of mother-child interactions (n = 140) were used to examine type of support for numerical concepts. Maternal support that involved labeling the quantities of sets of objects was predictive of later child math achievement. This association was significant for preschool (d = .45) and first-grade math (d = .49), controlling for other forms of numerical support (identifying numerals, one-to-one counting) as well as potential confounding factors. The importance of maternal support of labeling set sizes at 36 months is discussed as a precursor to children's eventual understanding of the cardinal principle. © 2016 The Authors. Child Development © 2016 Society for Research in Child Development, Inc.

  1. Flexoelectric effect in functionally graded materials: A numerical study

    NASA Astrophysics Data System (ADS)

    Kumar, Anuruddh; Kiran, Raj; Kumar, Rajeev; Chandra Jain, Satish; Vaish, Rahul

    2018-04-01

    The flexoelectric effect has been observed in a wide range of dielectric materials. However, the flexoelectric effect can only be induced using the strain gradient. Researchers have examined the flexoelectricity using non-uniform loading (cantilever type) or non-uniform shape in dielectric materials, which may be undesirable in many applications. In the present article, we demonstrate induced flexoelectricity in dielectric functionally graded materials (FGMs) due to non-uniform Youngs's modulus along the thickness. To examine flexoelectricity, Ba0.6Sr0.4TiO3 (BST) and polyvinylidene fluoride (PVDF) were used to numerically simulate the performance of FGMs. 2D simulation suggests that output voltage can drastically enhance for optimum grading index of FGMs.

  2. CSMP Mathematics for the Upper Primary Grades Part I, Teacher's Guide. The Languages of Strings and Arrows. Geometry and Measurement. Workbooks. Final Experimental Version.

    ERIC Educational Resources Information Center

    CEMREL, Inc., St. Ann, MO.

    This guide represents the final experimental version of a pilot project conducted in the Unites States between 1973 and 1976. The ideas and manner of presentation are based on the works of Georges and Frederique Papy. They are recognized as having introduced colored arrow drawings ("papygrams") and models of our numeration system (the…

  3. The Association between Standards- Based Grading and Standardized Test Scores in a High School Reform Model

    ERIC Educational Resources Information Center

    Pollio, Marty; Hochbein, Craig

    2015-01-01

    Background/Context: From two decades of research on the grading practices of teachers in secondary schools, researchers discovered that teachers evaluated students on numerous factors that do not validly assess a student's achievement level in a specific content area. These consistent findings suggested that traditional grading practices evolved…

  4. Art Education Curriculum Guide, K-12.

    ERIC Educational Resources Information Center

    Naperville Public Schools, IL.

    GRADES OR AGES: K-12. SUBJECT MATTER: Art. ORGANIZATION AND PHYSICAL APPEARANCE: The guide is divided into numerous sections, one each for grades K-8, and one section for grades 9-12. Each section is in list form. The guide is mimeographed and spiral-bound with a paper cover. OBJECTIVES AND ACTIVITIES: Each section contains four sample lessons…

  5. Mechanisms of double stratification and magnetic field in flow of third grade fluid over a slendering stretching surface with variable thermal conductivity

    NASA Astrophysics Data System (ADS)

    Hayat, Tasawar; Qayyum, Sajid; Alsaedi, Ahmed; Ahmad, Bashir

    2018-03-01

    This article addresses the magnetohydrodynamic (MHD) stagnation point flow of third grade fluid towards a nonlinear stretching sheet. Energy expression is based through involvement of variable thermal conductivity. Heat and mass transfer aspects are described within the frame of double stratification effects. Boundary layer partial differential systems are deduced. Governing systems are then converted into ordinary differential systems by invoking appropriate variables. The transformed expressions are solved through homotopic technique. Impact of embedded variables on velocity, thermal and concentration fields are displayed and argued. Numerical computations are presented to obtain the results of skin friction coefficient and local Nusselt and Sherwood numbers. It is revealed that larger values of magnetic parameter reduces the velocity field while reverse situation is noticed due to wall thickness variable. Temperature field and local Nusselt number are quite reverse for heat generation/absorption parameter. Moreover qualitative behaviors of concentration field and local Sherwood number are similar for solutal stratification parameter.

  6. Dynamic Response of Functionally Graded Carbon Nanotube Reinforced Sandwich Plate

    NASA Astrophysics Data System (ADS)

    Mehar, Kulmani; Panda, Subrata Kumar

    2018-03-01

    In this article, the dynamic response of the carbon nanotube-reinforced functionally graded sandwich composite plate has been studied numerically with the help of finite element method. The face sheets of the sandwich composite plate are made of carbon nanotube- reinforced composite for two different grading patterns whereas the core phase is taken as isotropic material. The final properties of the structure are calculated using the rule of mixture. The geometrical model of the sandwich plate is developed and discretized suitably with the help of available shell element in ANSYS library. Subsequently, the corresponding numerical dynamic responses computed via batch input technique (parametric design language code in ANSYS) of ANSYS including Newmark’s integration scheme. The stability of the sandwich structural numerical model is established through the proper convergence study. Further, the reliability of the sandwich model is checked by comparison study between present and available results from references. As a final point, some numerical problems have been solved to examine the effect of different design constraints (carbon nanotube distribution pattern, core to face thickness ratio, volume fractions of the nanotube, length to thickness ratio, aspect ratio and constraints at edges) on the time-responses of sandwich plate.

  7. Heterotopic ossification and clinical outcome in nonconstrained cervical arthroplasty 2 years after surgery: the Norwegian Cervical Arthroplasty Trial (NORCAT).

    PubMed

    Sundseth, Jarle; Jacobsen, Eva Astrid; Kolstad, Frode; Sletteberg, Ruth O; Nygaard, Oystein P; Johnsen, Lars Gunnar; Pripp, Are Hugo; Andresen, Hege; Fredriksli, Oddrun Anita; Myrseth, Erling; Zwart, John A

    2016-07-01

    Heterotopic ossification is a phenomenon in cervical arthroplasty. Previous reports have mainly focused on various semiconstrained devices and only a few publications have focused on ossification around devices that are nonconstrained. The purpose of this study was to assess the occurrence of heterotopic ossification around a nonconstrained cervical device and how it affects clinical outcome 2 years after surgery. Thirty-seven patients were included from a larger cohort of a randomized controlled trial (NORCAT) which compared single-level cervical arthroplasty with fusion. The occurrence of heterotopic ossification was assessed with a CT scan and two neuroradiologists determined its degree. For grading, we used the Mehren/Suchomel classification system (grade 0-4). The patients were divided by level of ossification, low grade (0-2) or high grade (3-4), and clinical outcomes were compared. Self-rated disability for neck and arm pain (Neck Disability Index), health-related quality of life (the Short Form-36 and EuroQol-5D), and pain (the Numeric Rating Scale 11) were used as clinical outcome measures. Heterotopic ossification was encountered in all patients 2 years after surgery. Complete fusion (grade 4) was found in 16 % of participants, and high-grade ossification (grade 3-4) occurred in 62 %. The remaining patients were classified as having low-grade ossification (grade 2). There were no differences in the clinical outcomes of patients with low- and high-grade ossification. High-grade heterotopic ossification and spontaneous fusion 2 years after surgery were seen in a significant number of patients. However, the degree of ossification did not influence the clinical outcome.

  8. FIBER AND INTEGRATED OPTICS: Emission properties of graded-index corrugated waveguides with a metal or semiconductor coating

    NASA Astrophysics Data System (ADS)

    Ataya, B. A.; Osovitskiĭ, A. N.

    1992-02-01

    A numerical method was used to investigate the emission of TE-polarized light from a graded-index corrugated waveguide coated with a metal or semiconductor and either with or without a buffer layer. The main emission characteristics of these systems were analyzed. In the case of metallized dielectric structures an optimal corrugation depth was established for which the emitted power is a maximum. It was found that when the parameters of a structure with a buffer layer were correctly chosen and a highly reflective metal coating was used, practically all the power in the waveguide wave could be emitted along a specified direction. A structure with a buffer layer and an aluminum coating was investigated experimentally.

  9. Teaching Middle-Grades Mathematics through Financial Literacy

    ERIC Educational Resources Information Center

    Crawford-Ferre, Heather Glynn; Wiest, Lynda R.; Vega, Stephanie

    2016-01-01

    Because financial literacy is an important skill for middle-grades students, this article suggests numerous personal financial literacy tasks for use in the mathematics classroom. Also provided are specifics for implementing one of these tasks to address mathematical content.

  10. Use of traffic channelization devices at highway-rail grade crossings

    DOT National Transportation Integrated Search

    2012-08-31

    Traffic channelization devices have found new application at highway-rail grade crossings with active warning devices. Numerous studies conducted at locations where they have been installed show positive changes in unsafe driver behavior as a result ...

  11. Developmental and Individual Differences in Pure Numerical Estimation

    ERIC Educational Resources Information Center

    Booth, Julie L.; Siegler, Robert S.

    2006-01-01

    The authors examined developmental and individual differences in pure numerical estimation, the type of estimation that depends solely on knowledge of numbers. Children between kindergarten and 4th grade were asked to solve 4 types of numerical estimation problems: computational, numerosity, measurement, and number line. In Experiment 1,…

  12. Successful Transition to High School: A Randomized Controlled Trial of the Barr Model with 9th Grade Students

    ERIC Educational Resources Information Center

    Corsello, Maryann; Sharma, Anu; Jerabek, Angela

    2015-01-01

    Ninth grade is a pivotal year for students. Numerous studies find that academic performance in 9th grade often sets the student's trajectory throughout the high school years, as well as the probability of graduation. The Building Assets Reducing Risks (BARR) model is a comprehensive approach that addresses developmental, academic, and school…

  13. The Impact of School-to-School Transitions on Academic Achievement: An Analysis of Various Grade-Span Configurations Utilized by Public School Districts in New York State

    ERIC Educational Resources Information Center

    DelViscio, James J.

    2013-01-01

    At the beginning of the 20th century, there were essentially two types of organizational structures for primary and secondary education in the United States. There were either one-room K-12 schools or in larger systems K-8 buildings feeding into four-year high schools. Despite numerous experiments since then in reconfiguring schools resulting in a…

  14. A hybrid neural networks-fuzzy logic-genetic algorithm for grade estimation

    PubMed Central

    Tahmasebi, Pejman; Hezarkhani, Ardeshir

    2012-01-01

    The grade estimation is a quite important and money/time-consuming stage in a mine project, which is considered as a challenge for the geologists and mining engineers due to the structural complexities in mineral ore deposits. To overcome this problem, several artificial intelligence techniques such as Artificial Neural Networks (ANN) and Fuzzy Logic (FL) have recently been employed with various architectures and properties. However, due to the constraints of both methods, they yield the desired results only under the specific circumstances. As an example, one major problem in FL is the difficulty of constructing the membership functions (MFs).Other problems such as architecture and local minima could also be located in ANN designing. Therefore, a new methodology is presented in this paper for grade estimation. This method which is based on ANN and FL is called “Coactive Neuro-Fuzzy Inference System” (CANFIS) which combines two approaches, ANN and FL. The combination of these two artificial intelligence approaches is achieved via the verbal and numerical power of intelligent systems. To improve the performance of this system, a Genetic Algorithm (GA) – as a well-known technique to solve the complex optimization problems – is also employed to optimize the network parameters including learning rate, momentum of the network and the number of MFs for each input. A comparison of these techniques (ANN, Adaptive Neuro-Fuzzy Inference System or ANFIS) with this new method (CANFIS–GA) is also carried out through a case study in Sungun copper deposit, located in East-Azerbaijan, Iran. The results show that CANFIS–GA could be a faster and more accurate alternative to the existing time-consuming methodologies for ore grade estimation and that is, therefore, suggested to be applied for grade estimation in similar problems. PMID:25540468

  15. 7 CFR 51.1216 - Size requirements.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... Standards for Grades of Peaches Size § 51.1216 Size requirements. (a) The numerical count or a count-size... closed container shall be indicated on the container. (b) When the numerical count is not shown the...

  16. 7 CFR 51.1216 - Size requirements.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... Standards for Grades of Peaches Size § 51.1216 Size requirements. (a) The numerical count or a count-size... closed container shall be indicated on the container. (b) When the numerical count is not shown the...

  17. 7 CFR 51.1216 - Size requirements.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... Standards for Grades of Peaches Size § 51.1216 Size requirements. (a) The numerical count or a count-size... closed container shall be indicated on the container. (b) When the numerical count is not shown the...

  18. Developmental Foundations of Children’s Fraction Magnitude Knowledge

    PubMed Central

    Mou, Yi; Li, Yaoran; Hoard, Mary K.; Nugent, Lara D.; Chu, Felicia W.; Rouder, Jeffrey N.; Geary, David C.

    2016-01-01

    The conceptual insight that fractions represent magnitudes is a critical yet daunting step in children’s mathematical development, and the knowledge of fraction magnitudes influences children’s later mathematics learning including algebra. In this study, longitudinal data were analyzed to identify the mathematical knowledge and domain-general competencies that predicted 8th and 9th graders’ (n=122) knowledge of fraction magnitudes and its cross-grade gains. Performance on the fraction magnitude measures predicted 9th grade algebra achievement. Understanding and fluently identifying the numerator-denominator relation in 7th grade emerged as the key predictor of later fraction magnitudes knowledge in both 8th and 9th grades. Competence at using fraction procedures, knowledge of whole number magnitudes, and the central executive contributed to 9th but not 8th graders’ fraction magnitude knowledge, and knowledge of whole number magnitude contributed to cross-grade gains. The key results suggest fluent processing of numerator-denominator relations presages students’ understanding of fractions as magnitudes and that the integration of whole number and fraction magnitudes occurs gradually. PMID:27773965

  19. Aeroelastic Tailoring of a Plate Wing with Functionally Graded Materials

    NASA Technical Reports Server (NTRS)

    Dunning, Peter D.; Stanford, Bret K.; Kim, H. Alicia; Jutte, Christine V.

    2014-01-01

    This work explores the use of functionally graded materials for the aeroelastic tailoring of a metallic cantilevered plate-like wing. Pareto trade-off curves between dynamic stability (flutter) and static aeroelastic stresses are obtained for a variety of grading strategies. A key comparison is between the effectiveness of material grading, geometric grading (i.e., plate thickness variations), and using both simultaneously. The introduction of material grading does, in some cases, improve the aeroelastic performance. This improvement, and the physical mechanism upon which it is based, depends on numerous factors: the two sets of metallic material parameters used for grading, the sweep of the plate, the aspect ratio of the plate, and whether the material is graded continuously or discretely.

  20. Sources of Individual Differences in Emerging Competence with Numeration Understanding versus Multidigit Calculation Skill

    ERIC Educational Resources Information Center

    Fuchs, Lynn S.; Geary, David C.; Fuchs, Douglas; Compton, Donald L.; Hamlett, Carol L.

    2014-01-01

    This study investigated contributions of general cognitive abilities and foundational mathematical competencies to numeration understanding (i.e., base-10 structure) versus multidigit calculation skill. Children (n = 394, M = 6.5 years) were assessed on general cognitive abilities and foundational numerical competencies at start of 1st grade; on…

  1. The Effects of Background Music in the Classroom on the Productivity, Motivation, and Behavior of Fourth Grade Students

    ERIC Educational Resources Information Center

    White, Kevin N.

    2007-01-01

    Many students in a fourth grade classroom at Logan Elementary School are expressing numerous types of negative behaviors, are not motivated to learn, and do not stay on-task. In an effort to change these students, an action research study was conducted that implemented background music in the classroom. There were ten fourth grade students who…

  2. Is There a Drop in Normative Clearsightedness in Sixth Grade? Study of Internality and Normative Clearsightedness in Fourth to Seventh Graders

    ERIC Educational Resources Information Center

    Bigot, Johann; Pichot, Nathalie; Teste, Benoit

    2004-01-01

    Numerous studies have demonstrated a decrease in the expression of internality in French sixth graders as compared to fifth graders. The present study examines normative clearsightedness in addition to internality across four French school grades (fourth to seventh). The results confirmed the sixth-grade drop in internality and showed that the…

  3. 7 CFR 51.311 - Marking requirements.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... (INSPECTION, CERTIFICATION, AND STANDARDS) United States Standards for Grades of Apples Marking Requirements...), grade, and the numerical count or minimum diameter of apples packed in a closed container shall be indicated on the container. For apple lots utilizing the combined diameter/weight designations for Red...

  4. 7 CFR 51.311 - Marking requirements.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... (INSPECTION, CERTIFICATION, AND STANDARDS) United States Standards for Grades of Apples Marking Requirements...), grade, and the numerical count or minimum diameter of apples packed in a closed container shall be indicated on the container. For apple lots utilizing the combined diameter/weight designations for Red...

  5. Effect of a Diffusion Zone on Fatigue Crack Propagation in Layered FGMs

    NASA Astrophysics Data System (ADS)

    Hauber, Brett; Brockman, Robert; Paulino, Glaucio

    2008-02-01

    Research into functionally graded materials (FGMs) has led to advances in our ability to analyze cracks. However, two prominent aspects remain relatively unexplored: 1) development and validation of modeling methods for fatigue crack propagation in FGMs, and 2) experimental validation of stress intensity models in engineered materials such as two phase monolithic and graded materials. This work addresses some of these problems for a limited set of conditions, material systems (e.g., Ti/TiB), and material gradients. Numerical analyses are conducted for single edge notch bend (SENB) specimens. Stress intensity factors are computed using the specialized finite element code I-Franc (Illinois Fracture Analysis Code), which is tailored for both homogeneous and graded materials, as well as Franc2DL and ABAQUS. Crack extension is considered by means of specified crack increments, together with fatigue evaluations to predict crack propagation life. Results will be used to determine linear material gradient parameters that are significant for prediction of fatigue crack growth behavior.

  6. Pathological Gleason prediction through gland ring morphometry in immunofluorescent prostate cancer images

    NASA Astrophysics Data System (ADS)

    Scott, Richard; Khan, Faisal M.; Zeineh, Jack; Donovan, Michael; Fernandez, Gerardo

    2016-03-01

    The Gleason score is the most common architectural and morphological assessment of prostate cancer severity and prognosis. There have been numerous quantitative techniques developed to approximate and duplicate the Gleason scoring system. Most of these approaches have been developed in standard H and E brightfield microscopy. Immunofluorescence (IF) image analysis of tissue pathology has recently been proven to be extremely valuable and robust in developing prognostic assessments of disease, particularly in prostate cancer. There have been significant advances in the literature in quantitative biomarker expression as well as characterization of glandular architectures in discrete gland rings. In this work we leverage a new method of segmenting gland rings in IF images for predicting the pathological Gleason; both the clinical and the image specific grade, which may not necessarily be the same. We combine these measures with nuclear specific characteristics as assessed by the MST algorithm. Our individual features correlate well univariately with the Gleason grades, and in a multivariate setting have an accuracy of 85% in predicting the Gleason grade. Additionally, these features correlate strongly with clinical progression outcomes (CI of 0.89), significantly outperforming the clinical Gleason grades (CI of 0.78). This work presents the first assessment of morphological gland unit features from IF images for predicting the Gleason grade.

  7. Methodology for Selection of Optimum Light Stringers in Functionally Graded Panels Designed for Prescribed Fundamental Frequency or Buckling Load

    NASA Astrophysics Data System (ADS)

    Birman, Victor; Byrd, Larry W.

    2008-02-01

    The interest to functionally graded materials (FGM) and structures has been generated by their potential advantages, including enhanced thermal properties, reduced or eliminated delamination concerns, a potential for an improved stress distribution, etc. Various aspects of the processing, design, micromechanics and analysis of FGM have been outlined in a number of reviews, mentioned here are [1-3]. In particular, functionally graded panels may be advantageous compared to their conventional counterparts in numerous applications. However, a typical FGM panel is asymmetric about its middle plane resulting in lower buckling loads and fundamental frequencies as well as higher stresses and deformations than the counterpart with a symmetric distribution of the same constituents. The reduced stiffness of FGM panels can be compensated by reinforcing them with stringers. For example, metallic stringers at the metal-rich surface of a FGM ceramic-metal panel may provide an efficient solution enabling a designer to increase both buckling loads as well as natural frequencies. The list of studies on optimization of FGM is extensive as could be anticipated for such tailored structural elements. For example, recent papers by Batra and his collaborators present optimization of the natural frequencies of a FGM plate through material grading [4] and through the graded fiber orientation [5]. The present paper is concerned with an optimum design of the system of stringers for a specified FGM panel. The task is to design the lightest system of stringers enabling the panel to achieve prescribed buckling loads or fundamental frequency.

  8. Student performance and course evaluations before and after use of the Classroom Performance System ™ in a third-year veterinary radiology course.

    PubMed

    Hecht, Silke; Adams, W H; Cunningham, M A; Lane, I F; Howell, N E

    2013-01-01

    Effective teaching of veterinary radiology can be challenging in a traditional classroom environment. Audience response systems, colloquially known as "clickers," provide a means of encouraging student interaction. The purpose of this study was to compare student performance and course evaluations before and after using the Classroom Performance System™ in the third-year (fifth semester) didactic radiology course at the University of Tennessee College of Veterinary Medicine. Overall student performance was assessed by comparing median numeric final course grades (%) between years without and with use of the Classroom Performance System™. Grades of students were determined for individual instructors' sections. Student evaluations of the radiology course were compared for the years available (2007-2010). Student interactions were also evaluated subjectively by instructors who used the Classroom Performance System™. There was a significant difference (p = 0.009) between the median student grade before (2005 - 2008, median 82.2%; interquartile range 77.6-85.7%; range 61.9-95.5%) and after use of the classroom performance system (2009-2010, median 83.6%; interquartile range 79.9-87.9%; range 68.2-93.2%). There was no statistically significant difference in median student grades for individual instructors over the study period. The radiology course student evaluation scores were significantly higher in years where the Classroom Performance System™ was used in comparison to previous years (P = 0.019). Subjectively, students appeared more involved when using clickers. Findings indicated that the Classroom Performance System™ may be a useful tool for enhancing veterinary radiology education. © 2012 Veterinary Radiology & Ultrasound.

  9. Teacher's Guide, Ecology, Grade 7.

    ERIC Educational Resources Information Center

    Yadkin Valley Economic Development District, Inc., Walnut Cove, NC.

    This teacher's guide has been constructed to assist in developing and implementing a life science course with an environment/ecological unit for Grade 7. Designed primarily for use with other science units, it offers numerous multidisciplinary activities which emphasize involvement in problem-solving through open-ended investigation rather than…

  10. Teacher's Guide, Ecology, Grade 10.

    ERIC Educational Resources Information Center

    Yadkin Valley Economic Development District, Inc., Walnut Cove, NC.

    This teacher's guide has been constructed to assist in developing and implementing a life science course with an environment/ecological unit for Grade 10. Designed primarily for use with other science units, it offers numerous multidisciplinary activities which emphasize involvement in problem-solving through open-ended investigation rather than…

  11. Finite element analysis of functionally graded bone plate at femur bone fracture site

    NASA Astrophysics Data System (ADS)

    Satapathy, Pravat Kumar; Sahoo, Bamadev; Panda, L. N.; Das, S.

    2018-03-01

    This paper focuses on the analysis of fractured Femur bone with functionally graded bone plate. The Femur bone is modeled by using the data from the CT (Computerized Tomography) scan and the material properties are assigned using Mimics software. The fracture fixation plate used here is composed of Functionally Graded Material (FGM). The functionally graded bone plate is considered to be composed of different layers of homogeneous materials. Finite element method approach is adopted for analysis. The volume fraction of the material is calculated by considering its variation along the thickness direction (z) according to a power law and the effective properties of the homogeneous layers are estimated. The model developed is validated by comparing numerical results available in the literature. Static analysis has been performed for the bone plate system by considering both axial compressive load and torsional load. The investigation shows that by introducing FG bone plate instead of titanium, the stress at the fracture site increases by 63 percentage and the deformation decreases by 15 percentage, especially when torsional load is taken into consideration. The present model yields better results in comparison with the commercially available bone plates.

  12. Teaching for Different Learning Styles.

    ERIC Educational Resources Information Center

    Cropper, Carolyn

    1994-01-01

    This study examined learning styles in 137 high ability fourth-grade students. All students were administered two learning styles inventories. Characteristics of students with the following learning styles are summarized: auditory language, visual language, auditory numerical, visual numerical, tactile concrete, individual learning, group…

  13. Theoretical and experimental investigations of asymmetric light transport in graded index photonic crystal waveguides

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Giden, I. H., E-mail: igiden@etu.edu.tr; Yilmaz, D.; Turduev, M.

    To provide asymmetric propagation of light, we propose a graded index photonic crystal (GRIN PC) based waveguide configuration that is formed by introducing line and point defects as well as intentional perturbations inside the structure. The designed system utilizes isotropic materials and is purely reciprocal, linear, and time-independent, since neither magneto-optical materials are used nor time-reversal symmetry is broken. The numerical results show that the proposed scheme based on the spatial-inversion symmetry breaking has different forward (with a peak value of 49.8%) and backward transmissions (4.11% at most) as well as relatively small round-trip transmission (at most 7.11%) in amore » large operational bandwidth of 52.6 nm. The signal contrast ratio of the designed configuration is above 0.80 in the telecom wavelengths of 1523.5–1576.1 nm. An experimental measurement is also conducted in the microwave regime: A strong asymmetric propagation characteristic is observed within the frequency interval of 12.8 GHz–13.3 GHz. The numerical and experimental results confirm the asymmetric transmission behavior of the proposed GRIN PC waveguide.« less

  14. Numerical Study on Natural Vacuum Solar Desalination System with Varying Heat Source Temperature

    NASA Astrophysics Data System (ADS)

    Ambarita, H.

    2017-03-01

    A natural vacuum desalination unit with varying low grade heat source temperature is investigated numerically. The objective is to explore the effects of the variable temperature of the low grade heat source on performances and characteristics of the desalination unit. The specifications of the desalination unit are naturally vacuumed with surface area of seawater in evaporator and heating coil are 0.2 m2 and 0.188 m2, respectively. Temperature of the heating coil is simulated based on the solar radiation in the Medan city. A program to solve the governing equations in forward time step marching technique is developed. Temperature of the evaporator, fresh water production rate, and thermal efficiency of the desalination unit are analysed. Simulation is performed for 9 hours, it starts from 8.00 and finishes at 17.00 of local time. The results show that, the desalination unit with operation time of 9 hours can produce 5.705 L of freshwater and thermal efficiency is 81.8 %. This reveals that varying temperature of the heat source of natural vacuum desalination unit shows better performance in comparison with constant temperature of the heat source.

  15. Analytical solution for wave propagation through a graded index interface between a right-handed and a left-handed material.

    PubMed

    Dalarsson, Mariana; Tassin, Philippe

    2009-04-13

    We have investigated the transmission and reflection properties of structures incorporating left-handed materials with graded index of refraction. We present an exact analytical solution to Helmholtz' equation for a graded index profile changing according to a hyperbolic tangent function along the propagation direction. We derive expressions for the field intensity along the graded index structure, and we show excellent agreement between the analytical solution and the corresponding results obtained by accurate numerical simulations. Our model straightforwardly allows for arbitrary spectral dispersion.

  16. Spatial Modeling of Geometallurgical Properties: Techniques and a Case Study

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Deutsch, Jared L., E-mail: jdeutsch@ualberta.ca; Palmer, Kevin; Deutsch, Clayton V.

    High-resolution spatial numerical models of metallurgical properties constrained by geological controls and more extensively by measured grade and geomechanical properties constitute an important part of geometallurgy. Geostatistical and other numerical techniques are adapted and developed to construct these high-resolution models accounting for all available data. Important issues that must be addressed include unequal sampling of the metallurgical properties versus grade assays, measurements at different scale, and complex nonlinear averaging of many metallurgical parameters. This paper establishes techniques to address each of these issues with the required implementation details and also demonstrates geometallurgical mineral deposit characterization for a copper–molybdenum deposit inmore » South America. High-resolution models of grades and comminution indices are constructed, checked, and are rigorously validated. The workflow demonstrated in this case study is applicable to many other deposit types.« less

  17. Varieties of Quantity Estimation in Children

    ERIC Educational Resources Information Center

    Sella, Francesco; Berteletti, Ilaria; Lucangeli, Daniela; Zorzi, Marco

    2015-01-01

    In the number-to-position task, with increasing age and numerical expertise, children's pattern of estimates shifts from a biased (nonlinear) to a formal (linear) mapping. This widely replicated finding concerns symbolic numbers, whereas less is known about other types of quantity estimation. In Experiment 1, Preschool, Grade 1, and Grade 3…

  18. Everyday Mathematics. Revised. What Works Clearinghouse Intervention Report

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2007

    2007-01-01

    "Everyday Mathematics," published by Wright Group/McGraw-Hill, is a core curriculum for students in kindergarten through grade 6 covering numeration and order, operations, functions and sequences, data and chance, algebra, geometry and spatial sense, measures and measurement, reference frames, and patterns. At each grade level, the…

  19. Everyday Mathematics. What Works Clearinghouse Intervention Report

    ERIC Educational Resources Information Center

    What Works Clearinghouse, 2006

    2006-01-01

    "Everyday Mathematics," published by Wright Group/McGraw-Hill, is a core curriculum for students in kindergarten through grade 6 covering numeration and order, operations, functions and sequences, data and chance, algebra, geometry and spatial sense, measures and measurement, reference frames, and patterns. At each grade level, the "Everyday…

  20. Variability of Passing Grades in Undergraduate Nursing Education Programs in New York State.

    PubMed

    Reynolds, Diane

    2015-01-01

    The purpose of this descriptive study was to provide information about passing grades and their corresponding numeric grades for undergraduate nursing programs in New York State. An additional purpose was to report on differences in grading between faculty teaching in associate versus baccalaureate nursing programs, full-time versus adjunct faculty, and tenured versus nontenured faculty. There is a paucity of research on grade variability in undergraduate nursing programs. Three hundred eighty-four full-time and 96 adjunct faculty responded to an invitation to complete an online survey. Grades are not uniformly awarded across institutions. Passing grades ranged from 70 to 85 percent (C- to B+, respectively), with a mean of 74.79 percent. Wide variations in grades in different institutions across the country may undermine grade point average as a reliable measure of education, making it difficult to evaluate individual student performance.

  1. Overview of classification systems in peripheral artery disease.

    PubMed

    Hardman, Rulon L; Jazaeri, Omid; Yi, J; Smith, M; Gupta, Rajan

    2014-12-01

    Peripheral artery disease (PAD), secondary to atherosclerotic disease, is currently the leading cause of morbidity and mortality in the western world. While PAD is common, it is estimated that the majority of patients with PAD are undiagnosed and undertreated. The challenge to the treatment of PAD is to accurately diagnose the symptoms and determine treatment for each patient. The varied presentations of peripheral vascular disease have led to numerous classification schemes throughout the literature. Consistent grading of patients leads to both objective criteria for treating patients and a baseline for clinical follow-up. Reproducible classification systems are also important in clinical trials and when comparing medical, surgical, and endovascular treatment paradigms. This article reviews the various classification systems for PAD and advantages to each system.

  2. Exploring the Causes of Underachievement of African American Boys: A Qualitative Descriptive Case Study

    ERIC Educational Resources Information Center

    Ennis, Rosetta

    2017-01-01

    The qualitative descriptive case study explores the underachievement phenomenon of fourth-grade African American boys in New York City public elementary schools. Numerous studies have been conducted at the middle school through college levels. However, very little is known about the underachievement phenomenon of fourth-grade African American…

  3. A Dogrib History. Grade 4-6.

    ERIC Educational Resources Information Center

    Fraser, Tara

    A publication on the history and traditional lifestyle of the Dogrib Tribe of Canada's Northwest Territories is intended for use in grades 4-6. The text is illustrated with numerous drawings. Sections describe the caribou, spruce tree, muskox, fox, ducks and geese and their usefulness to Dogrib people. Activities covered are trading at the trading…

  4. Thai Grade 10 and 11 Students' Conceptual Understanding and Ability to Solve Stoichiometry Problems

    ERIC Educational Resources Information Center

    Dahsah, Chanyah; Coll, Richard K.

    2007-01-01

    Stoichiometry and related concepts are an important part of student learning in chemistry. In this interpretive-based inquiry, we investigated Thai Grade 10 and 11 students' conceptual understanding and ability to solve numerical problems for stoichiometry-related concepts. Ninety-seven participants completed a purpose-designed survey instrument…

  5. Water: A Vital Resource. Environmental Education Supplementary Instructional Guide. Sixth Grade Level.

    ERIC Educational Resources Information Center

    Young, Donald B.; And Others

    Water related activities for sixth-grade students are presented as one possible way to incorporate environmental education into the existing curriculum of Hawaii schools. Designed as an interdisciplinary approach, the activities integrate numerous thematic and subject areas to teach that fresh water is a limited but vital natural resource. Topics…

  6. Mathematical History: Activities, Puzzles, Stories, and Games.

    ERIC Educational Resources Information Center

    Mitchell, Merle

    Based on the history of mathematics, these materials have been planned to enrich the teaching of mathematics in grades four, five, and six. Puzzles and games are based on stories about topics such as famous mathematicians, numerals of ancient peoples, and numerology. The sheets are arranged by grade level and are designed for easy duplication.…

  7. Math Thinkercises. A Good Apple Math Activity Book for Students. Grades 4-8.

    ERIC Educational Resources Information Center

    Daniel, Becky

    This booklet designed for students in grades 4-8 provides 52 activities, including puzzles and problems. Activities range from simple to complex, giving learners practice in finding patterns, numeration, permutation, and problem solving. Calculators should be available, and students should be encouraged to discuss solutions with classmates,…

  8. Effect of concrete strength gradation to the compressive strength of graded concrete, a numerical approach

    NASA Astrophysics Data System (ADS)

    Pratama, M. Mirza Abdillah; Aylie, Han; Gan, Buntara Sthenly; Umniati, B. Sri; Risdanareni, Puput; Fauziyah, Shifa

    2017-09-01

    Concrete casting, compacting method, and characteristic of the concrete material determine the performance of concrete as building element due to the material uniformity issue. Previous studies show that gradation in strength exists on building member by nature and negatively influence the load carrying capacity of the member. A pilot research had modeled the concrete gradation in strength with controllable variable and observed that the weakest material determines the strength of graded concrete through uniaxial compressive loading test. This research intends to confirm the recent finding by a numerical approach with extensive variables of strength disparity. The finite element analysis was conducted using the Strand7 nonlinear program. The results displayed that the increase of strength disparity in graded concrete models leads to the slight reduction of models strength. A substantial difference in displacement response is encountered on the models for the small disparity of concrete strength. However, the higher strength of concrete mix in the graded concrete models contributes to the rise of material stiffness that provides a beneficial purpose for serviceability of building members.

  9. Free Vibration Characteristics of Functionally Graded Pre-twisted Conical Shells under Rotation

    NASA Astrophysics Data System (ADS)

    Das, Apurba; Karmakar, Amit

    2017-06-01

    This article deals with effect of rotation and pretwist angle on free vibration characteristics of functionally graded conical shells. The dynamic equilibrium equation is derived from Lagrange's equation neglecting the Coriolis effect for moderate rotational speeds. The materials properties of conical shell are varied with a power-law distribution of the volume fractions of their constituents through its thickness. Convergence studies are performed in respect of mesh sizes, and comparisons of the present solutions and those reported in open literature are provided to substantiate the accuracy of the proposed method. Computer codes developed to obtain the numerical results for the combined effects of twist angle and rotational speed on the natural frequencies of functionally graded conical shells. The mode shapes for a typical laminate configuration under different conditions are also illustrated. Numerical results are obtained for the non-dimensional fundamental (NDFF) and second frequencies (NDSF).

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roberts, Barry L; Lord, David; Lord, Anna C. Snider

    This report summarizes the work performed in the prioritization of cavern access wells for remediation and monitoring at the West Hackberry Strategic Petroleum Reserve site. The grading included consideration of all 31 wells at the West Hackberry site, with each well receiving a separate grade for remediation and monitoring. Numerous factors affecting well integrity were incorporated into the grading including casing survey results, cavern pressure history, results from geomechanical simulations, and site geologic factors. The factors and grading framework used here are the same as those used in developing similar well remediation and monitoring priorities at the Big Hill andmore » Bryan Mound Strategic Petroleum Reserve Sites.« less

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roberts, Barry L; Lord, David; Lord, Anna C. Snider

    This report summarizes the work performed in the prioritization of cavern access wells for remediation and monitoring at the Bryan Mound Strategic Petroleum Reserve site. The grading included consideration of all 47 wells at the Bryan Mound site, with each well receiving a separate grade for remediation and monitoring. Numerous factors affecting well integrity were incorporated into the grading including casing survey results, cavern pressure history, results from geomechanical simulations, and site geologic factors. The factors and grading framework used here are the same as those used in developing similar well remediation and monitoring priorities at the Big Hill Strategicmore » Petroleum Reserve Site.« less

  12. Intellectual Abilities That Discriminate Good and Poor Problem Solvers.

    ERIC Educational Resources Information Center

    Meyer, Ruth Ann

    1981-01-01

    This study compared good and poor fourth-grade problem solvers on a battery of 19 "reference" tests for verbal, induction, numerical, word fluency, memory, perceptual speed, and simple visualization abilities. Results suggest verbal, numerical, and especially induction abilities are important to successful mathematical problem solving.…

  13. Quantitative Relationships Involving Additive Differences: Numerical Resilience

    ERIC Educational Resources Information Center

    Ramful, Ajay; Ho, Siew Yin

    2014-01-01

    This case study describes the ways in which problems involving additive differences with unknown starting quantities, constrain the problem solver in articulating the inherent quantitative relationship. It gives empirical evidence to show how numerical reasoning takes over as a Grade 6 student instantiates the quantitative relation by resorting to…

  14. Numerical analysis of helical dielectric elastomer actuator

    NASA Astrophysics Data System (ADS)

    Park, Jang Ho; Nair, Saurabh; Kim, Daewon

    2017-04-01

    Dielectric elastomer actuators (DEA) are known for its capability of experiencing extreme strains, as it can expand and contract based on specific actuation voltage applied. On contrary, helical DEA (HDEA) with its unique configuration does not only provide the contractile and extendable capabilities, but also can aid in attaining results for bending and torsion. The concept of HDEA embraces many new techniques and can be applied in multiple disciplines. Thus, this paper focuses on the simulation of HDEA with helical compliant electrodes that is a major factor prior to its application. The attributes of the material used to build the structure plays a vital role in the behavior of the system. For numerical analysis of HDEA, the material characteristics are input into a commercial grade software, and then the appropriate analysis is performed to retrieve its outcome. Applying the material characteristics into numerical analysis modeling, the functionality of HDEA for various activations can be achieved, which is used to test and comply with the fabricated final product.

  15. Quantitative method to assess caries via fluorescence imaging from the perspective of autofluorescence spectral analysis

    NASA Astrophysics Data System (ADS)

    Chen, Q. G.; Zhu, H. H.; Xu, Y.; Lin, B.; Chen, H.

    2015-08-01

    A quantitative method to discriminate caries lesions for a fluorescence imaging system is proposed in this paper. The autofluorescence spectral investigation of 39 teeth samples classified by the International Caries Detection and Assessment System levels was performed at 405 nm excitation. The major differences in the different caries lesions focused on the relative spectral intensity range of 565-750 nm. The spectral parameter, defined as the ratio of wavebands at 565-750 nm to the whole spectral range, was calculated. The image component ratio R/(G + B) of color components was statistically computed by considering the spectral parameters (e.g. autofluorescence, optical filter, and spectral sensitivity) in our fluorescence color imaging system. Results showed that the spectral parameter and image component ratio presented a linear relation. Therefore, the image component ratio was graded as <0.66, 0.66-1.06, 1.06-1.62, and >1.62 to quantitatively classify sound, early decay, established decay, and severe decay tissues, respectively. Finally, the fluorescence images of caries were experimentally obtained, and the corresponding image component ratio distribution was compared with the classification result. A method to determine the numerical grades of caries using a fluorescence imaging system was proposed. This method can be applied to similar imaging systems.

  16. Exploiting a Molecular Gleason Grade for Prostate Cancer Therapy

    DTIC Science & Technology

    2010-03-01

    clinical effectiveness of chemotherapy. MAOA influences chemotherapy resistance 3 INTRODUCTION Despite numerous clinical trials conducted...therapy resistance. Although residual viable tumor cells were identified in each case, chemotherapy effects were evident. We previously reported the...found that MAOA expression was upregulated in prostate cancers in association with higher Gleason grades (11), but effects on modulating cytotoxic drug

  17. SCOPE (Standardized Curriculum-Oriented Pupil Evaluation) Mathematics. Test Book Grade Five.

    ERIC Educational Resources Information Center

    Northwest Territories Dept. of Education, Yellowknife. Programs and Evaluation Branch.

    The SCOPE Mathematics Achievement Test booklet for grade 5 presents 11 mathematical concepts with instructions for students to take the test with little or no teacher direction. Testing items include: writing number words; reading and writing numerals in sequence from 0.001 to 100,000; adding and subtracting whole numbers; multiplying up to four…

  18. An Analysis of Kindergarten and First Grade Children's Addition and Subtraction Problem Solving Modeling and Accuracy.

    ERIC Educational Resources Information Center

    Shores, Jay H.; Underhill, Robert G.

    A study was undertaken of the effects of formal education and conservation of numerousness on addition and subtraction problem types. Thirty-six kindergarten and 36 first-grade subjects randomly selected from one area of a school district were administered measures of conservation, problem-solving success, and modeling ability. Following factor…

  19. Variables Associated with Grade R English Additional Language Acquisition in Multilingual Rural Mpumalanga Schools

    ERIC Educational Resources Information Center

    Moodley, P.; Kritzinger, A.; Vinck, B.

    2016-01-01

    In a previous study Moodley, Kritzinger and Vinck (2014) found that formal English Additional Language (EAL) instruction contributed significantly better to listening and speaking skills in Grade R learners, than did a play-based approach. The finding in multilingual rural Mpumalanga schools was in agreement with numerous studies elsewhere.…

  20. Beyond Grade Retention and Social Promotion: Promoting the Social and Academic Competence of Students

    ERIC Educational Resources Information Center

    Jimerson, Shane R.; Pletcher, Sarah M. W.; Graydon, Kelly; Schnurr, Britton L.; Nickerson, Amanda B.; Kundert, Deborah K.

    2006-01-01

    During the past decade, amidst the current context emphasizing educational standards and accountability, the practice of grade retention has increased. The call for an end to social promotion has generated a variety of recommendations and legislation regarding promotion policies. This context has served as a catalyst for numerous debates regarding…

  1. Physics 30: Grade 12 Diploma Examination, June 1997.

    ERIC Educational Resources Information Center

    Alberta Dept. of Education, Edmonton. Student Evaluation Branch.

    This document is a Physics 30 Grade 12 Diploma Examination from Alberta Education. It is a 2.5 hour closed-book examination consisting of 37 multiple-choice and 12 numerical-response questions of equal value worth 70% of the examination and two written-response questions of equal value worth 30% of the examination. The exam contains sets of…

  2. Strand IV Environmental and Community Health, Ecology and Epidemiology of Health, Grades 10, 11, and 12.

    ERIC Educational Resources Information Center

    New York State Education Dept., Albany. Bureau of Secondary Curriculum Development.

    A frame of reference concerning health implications, based on the interaction of numerous factors in the physical, social, and biological environments, is provided in this prototype curriculum for grades 10-12. Development of sound techniques in problem solving is encouraged, resulting from the need to understand the nature and complexities of…

  3. Adolescents’ Functional Numeracy Is Predicted by Their School Entry Number System Knowledge

    PubMed Central

    Geary, David C.; Hoard, Mary K.; Nugent, Lara; Bailey, Drew H.

    2013-01-01

    One in five adults in the United States is functionally innumerate; they do not possess the mathematical competencies needed for many modern jobs. We administered functional numeracy measures used in studies of young adults’ employability and wages to 180 thirteen-year-olds. The adolescents began the study in kindergarten and participated in multiple assessments of intelligence, working memory, mathematical cognition, achievement, and in-class attentive behavior. Their number system knowledge at the beginning of first grade was defined by measures that assessed knowledge of the systematic relations among Arabic numerals and skill at using this knowledge to solve arithmetic problems. Early number system knowledge predicted functional numeracy more than six years later (ß = 0.195, p = .0014) controlling for intelligence, working memory, in-class attentive behavior, mathematical achievement, demographic and other factors, but skill at using counting procedures to solve arithmetic problems did not. In all, we identified specific beginning of schooling numerical knowledge that contributes to individual differences in adolescents’ functional numeracy and demonstrated that performance on mathematical achievement tests underestimates the importance of this early knowledge. PMID:23382934

  4. Multimodal inspection in power engineering and building industries: new challenges and solutions

    NASA Astrophysics Data System (ADS)

    Kujawińska, Małgorzata; Malesa, Marcin; Malowany, Krzysztof

    2013-09-01

    Recently the demand and number of applications of full-field, optical measurement methods based on noncoherent light sources increased significantly. They include traditional image processing, thermovision, digital image correlation (DIC) and structured light methods. However, there are still numerous challenges connected with implementation of these methods to in-situ, long-term monitoring in industrial, civil engineering and cultural heritage applications, multimodal measurements of a variety of object features or simply adopting instruments to work in hard environmental conditions. In this paper we focus on 3D DIC method and present its enhancements concerning software modifications (new visualization methods and a method for automatic merging of data distributed in time) and hardware improvements. The modified 3D DIC system combined with infrared camera system is applied in many interesting cases: measurements of boiler drum during annealing and of pipelines in heat power stations and monitoring of different building steel struts at construction site and validation of numerical models of large building structures constructed of graded metal plate arches.

  5. The Age-Related Macular Degeneration Complex: Linking Epidemiology and Histopathology Using the Minnesota Grading System (The Inaugural Frederick C. Blodi Lecture).

    PubMed

    Olsen, Timothy W; Bottini, Alexander R; Mendoza, Pia; Grossniklausk, Hans E

    2015-09-01

    To describe the histopathologic findings of the four stages of age-related macular degeneration (AMD) as defined by the Age-Related Eye Disease Study (AREDS) using the Minnesota grading system (MGS). There are no animal models for AMD. Eye banks enable access to human tissue with AMD. The level of AMD (grades 1 through 4) as defined by AREDS is determined ex vivo using the MGS. The AREDS has the largest collection to date of prospectively gathered data on the natural history of AMD. Since the MGS uses the same clinical criteria as AREDS, the addition of histopathologic findings of graded tissue confirms important pathophysiology at each stage of AMD. Four eye bank eyes were graded according to the MGS. Only the right eyes were dissected for phenotype grading. The fellow (left) eyes were fixed for histopathologic study. The eyes were serially sectioned (7 μm) through the macula. Individual slides were examined, and a two-dimensional reconstruction of the topography of the macula was created for each donor. Selected, unstained slides were used for immunohistochemical staining. In one donor, portions of tissue were obtained for transmission electron microscopic (TEM) processing. Donor 1 had a rare hard, nodular druse (MGS1). Donor 2 had intermediate confluent drusen (MGS2). Donor 3 had numerous intermediate drusen (MGS3) in the right eye. Histopathology of the fellow left showed basal laminar deposits (BLamD), soft drusen, and an area of occult choroidal neovascularization underlying the retinal pigment epithelium (RPE) with endothelial cells (CD31-positive). Donor 4 also had MGS 3 along with reticular pseudodrusen (RPD). Histologic and TEM examination demonstrated diffuse BLamD, thickening of Bruch's membrane, hard drusen, and focal nodules underlying the RPE that corresponded to the RPD. EM examination demonstrated both BLamD and electron-dense material located just external to the elastic layer of Bruch's membrane. Eye bank eyes graded using the MGS serve as an important link to the phenotypic and epidemiologic data from the AREDS. Thus, the MGS serves as a system to study the histopathology at each stage of AMD to better understand the relevant pathophysiologic changes in disease progression.

  6. The Age-Related Macular Degeneration Complex: Linking Epidemiology and Histopathology Using the Minnesota Grading System (The Inaugural Frederick C. Blodi Lecture)

    PubMed Central

    Olsen, Timothy W.; Bottini, Alexander R.; Mendoza, Pia; Grossniklausk, Hans E.

    2015-01-01

    Purpose To describe the histopathologic findings of the four stages of age-related macular degeneration (AMD) as defined by the Age-Related Eye Disease Study (AREDS) using the Minnesota grading system (MGS). Clinical Relevance There are no animal models for AMD. Eye banks enable access to human tissue with AMD. The level of AMD (grades 1 through 4) as defined by AREDS is determined ex vivo using the MGS. The AREDS has the largest collection to date of prospectively gathered data on the natural history of AMD. Since the MGS uses the same clinical criteria as AREDS, the addition of histopathologic findings of graded tissue confirms important pathophysiology at each stage of AMD. Methods Four eye bank eyes were graded according to the MGS. Only the right eyes were dissected for phenotype grading. The fellow (left) eyes were fixed for histopathologic study. The eyes were serially sectioned (7 μm) through the macula. Individual slides were examined, and a two-dimensional reconstruction of the topography of the macula was created for each donor. Selected, unstained slides were used for immunohistochemical staining. In one donor, portions of tissue were obtained for transmission electron microscopic (TEM) processing. Results Donor 1 had a rare hard, nodular druse (MGS1). Donor 2 had intermediate confluent drusen (MGS2). Donor 3 had numerous intermediate drusen (MGS3) in the right eye. Histopathology of the fellow left showed basal laminar deposits (BLamD), soft drusen, and an area of occult choroidal neovascularization underlying the retinal pigment epithelium (RPE) with endothelial cells (CD31-positive). Donor 4 also had MGS 3 along with reticular pseudodrusen (RPD). Histologic and TEM examination demonstrated diffuse BLamD, thickening of Bruch’s membrane, hard drusen, and focal nodules underlying the RPE that corresponded to the RPD. EM examination demonstrated both BLamD and electron-dense material located just external to the elastic layer of Bruch’s membrane. Conclusion Eye bank eyes graded using the MGS serve as an important link to the phenotypic and epidemiologic data from the AREDS. Thus, the MGS serves as a system to study the histopathology at each stage of AMD to better understand the relevant pathophysiologic changes in disease progression. PMID:27895380

  7. Integrating spatial and numerical structure in mathematical patterning

    NASA Astrophysics Data System (ADS)

    Ni’mah, K.; Purwanto; Irawan, E. B.; Hidayanto, E.

    2018-03-01

    This paper reports a study monitoring the integrating spatial and numerical structure in mathematical patterning skills of 30 students grade 7th of junior high school. The purpose of this research is to clarify the processes by which learners construct new knowledge in mathematical patterning. Findings indicate that: (1) students are unable to organize the structure of spatial and numerical, (2) students were only able to organize the spatial structure, but the numerical structure is still incorrect, (3) students were only able to organize numerical structure, but its spatial structure is still incorrect, (4) students were able to organize both of the spatial and numerical structure.

  8. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Roberts, Barry L; Lord, David; Lord, Anna C. Snider

    This report summarizes the work performed in the prioritization of cavern access wells for remediation and monitoring at the Bayou Choctaw Strategic Petroleum Reserve site. The grading included consideration of all 15 wells at the Bayou Choctaw site, with each active well receiving a separate grade for remediation and monitoring. Numerous factors affecting well integrity were incorporated into the grading including casing survey results, cavern pressure history, results from geomechanical simulations, and site geologic factors. The factors and grading framework used here are the same as those used in developing similar well remediation and monitoring priorities at the Big Hill,more » Bryan Mound, and West Hackberry Strategic Petroleum Reserve Sites.« less

  9. Focused terahertz waves generated by a phase velocity gradient in a parallel-plate waveguide.

    PubMed

    McKinney, Robert W; Monnai, Yasuaki; Mendis, Rajind; Mittleman, Daniel

    2015-10-19

    We demonstrate the focusing of a free-space THz beam emerging from a leaky parallel-plate waveguide (PPWG). Focusing is accomplished by grading the launch angle of the leaky wave using a PPWG with gradient plate separation. Inside the PPWG, the phase velocity of the guided TE1 mode exceeds the vacuum light speed, allowing the wave to leak into free space from a slit cut along the top plate. Since the leaky wave angle changes as the plate separation decreases, the beam divergence can be controlled by grading the plate separation along the propagation axis. We experimentally demonstrate focusing of the leaky wave at a selected location at frequencies of 100 GHz and 170 GHz, and compare our measurements with numerical simulations. The proposed concept can be valuable for implementing a flat and wide-aperture beam-former for THz communications systems.

  10. Graded-index fiber tip optical tweezers: numerical simulation and trapping experiment.

    PubMed

    Gong, Yuan; Ye, Ai-Yan; Wu, Yu; Rao, Yun-Jiang; Yao, Yao; Xiao, Song

    2013-07-01

    Optical fiber tweezers based on a graded-index multimode fiber (GIMMF) tip is proposed. Light propagation characteristics and gradient force distribution near the GIMMF tip are numerically investigated, which are further compared with that of optical fiber tips based on conventional single mode fibers. The simulated results indicated that by selecting optimal GIMMF length, the gradient force of the GIMMF tip tweezers is about 4 times higher than that of the SMF tip tweezers with a same shape. To prove the feasibility of such a new concept, optical trapping of yeast cells with a diameter of ~5 μm using the chemically-etched GIMMF tip is experimentally demonstrated and the trapping force is also calculated.

  11. Numerical investigation of an all-optical switch in a graded nonlinear plasmonic grating.

    PubMed

    Wang, Guoxi; Lu, Hua; Liu, Xueming; Gong, Yongkang

    2012-11-09

    We have proposed and numerically investigated an all-optical switch based on a metal-insulator-metal waveguide with graded nonlinear plasmonic gratings. The influences of grating depth and refractive index of a Kerr nonlinear medium on the transmission of the switch are exactly analyzed by utilizing transmission line theory. The finite-difference time-domain simulation results show that the highly compact structure possesses excellent switch function by tuning the incident electric field intensity. In addition, the simulation results show that this all-optical switch has an ultrawide operating frequency regime and femtosecond-scale response time (~130 fs). Such a switch can find potential applications for all-optical signal processing and optical communication.

  12. Model validation using CFD-grade experimental database for NGNP Reactor Cavity Cooling Systems with water and air

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Manera, Annalisa; Corradini, Michael; Petrov, Victor

    This project has been focused on the experimental and numerical investigations of the water-cooled and air-cooled Reactor Cavity Cooling System (RCCS) designs. At this aim, we have leveraged an existing experimental facility at the University of Wisconsin-Madison (UW), and we have designed and built a separate effect test facility at the University of Michigan. The experimental facility at UW has underwent several upgrades, including the installation of advanced instrumentation (i.e. wire-mesh sensors) built at the University of Michigan. These provides highresolution time-resolved measurements of the void-fraction distribution in the risers of the water-cooled RCCS facility. A phenomenological model has beenmore » developed to assess the water cooled RCCS system stability and determine the root cause behind the oscillatory behavior that occurs under normal two-phase operation. Testing under various perturbations to the water-cooled RCCS facility have resulted in changes in the stability of the integral system. In particular, the effects on stability of inlet orifices, water tank volume have and system pressure been investigated. MELCOR was used as a predictive tool when performing inlet orificing tests and was able to capture the Density Wave Oscillations (DWOs) that occurred upon reaching saturation in the risers. The experimental and numerical results have then been used to provide RCCS design recommendations. The experimental facility built at the University of Michigan was aimed at the investigation of mixing in the upper plenum of the air-cooled RCCS design. The facility has been equipped with state-of-theart high-resolution instrumentation to achieve so-called CFD grade experiments, that can be used for the validation of Computational Fluid Dynanmics (CFD) models, both RANS (Reynold-Averaged) and LES (Large Eddy Simulations). The effect of risers penetration in the upper plenum has been investigated as well.« less

  13. Evaluation of a Numeracy Intervention Program Focusing on Basic Numerical Knowledge and Conceptual Knowledge: A Pilot Study.

    ERIC Educational Resources Information Center

    Kaufmann, Liane; Handl, Pia; Thony, Brigitte

    2003-01-01

    In this study, six elementary grade children with developmental dyscalculia were trained individually and in small group settings with a one-semester program stressing basic numerical knowledge and conceptual knowledge. All the children showed considerable and partly significant performance increases on all calculation components. Results suggest…

  14. The Contributions of Domain-General and Numerical Factors to Third-Grade Arithmetic Skills and Mathematical Learning Disability

    ERIC Educational Resources Information Center

    Cowan, Richard; Powell, Daisy

    2014-01-01

    Explanations of the marked individual differences in elementary school mathematical achievement and mathematical learning disability (MLD or dyscalculia) have involved domain-general factors (working memory, reasoning, processing speed, and oral language) and numerical factors that include single-digit processing efficiency and multidigit skills…

  15. [Acute injuries of lateral ankle joint ligaments].

    PubMed

    Lacko, M; Sidor, Z; Stolfa, S; Cellár, R; Vasko, G

    2010-08-01

    Acute injuries of the lateral ankle ligaments are one of the most common form of injury involving the musculoskeletal apparatus. Treatment usually range from cast immobilisation or acute surgical repair to functional rehabilitation. The aim of our study was to evaluate the incidence of different grades of acute injuries of lateral ligaments of the ankle joint in our patients group and to compare the results of non surgical versus surgical treatment of third grade injuries. 3148 patients were treated for acute lateral ankle sprain in a period of 5 years at our department. Each patient had stress X-ray of the ankle for evaluation of instability at the first visit. From the 234 patients with third grade injury, 39 were enrolled in our study with non surgical treatment and 18 with surgical treatment. Each group was divided regarding to the age in two subgroups. Functional outcome was evaluated 12 and 24 months after injury with AOFAS clinical rating scale and Sports Ankle Rating System--Single Assessment Numeric Evaluation. Statistical analysis was done with Pearson's Chi quadrate test with P < 0.05. First grade injury was present in 62%, second grade in 31% and only 7% of the patients had third grade injury of the lateral ankle ligaments. Further only third grade injuries were studied. Statistically significant better results were seen in patients under the age of 25, in the patient group with surgical treatment compared to patients over 25 years of age. Also statistically significant better results were seen in patient with surgical treatment to non surgical treatment in each age group. No significant difference was observed in the non surgical treatment group regarding to age. Although the injuries of the ankle ligaments belong to the most common injuries of the musculoskeletal system, there is no consensus in the treatment of such disorders. Our experiences and the results of our study show, that surgical treatment in indicated cases provides better results in residual pain and instability of the ankle joint after acute injury of the lateral ankle ligaments.;

  16. Classification, Seriation, and Counting in Grades 1, 2, and 3 as Two-Year Longitudinal Predictors for Low Achieving in Numerical Facility and Arithmetical Achievement?

    ERIC Educational Resources Information Center

    Desoete, Annemie; Stock, Pieter; Schepens, Annemie; Baeyens, Dieter; Roeyers, Herbert

    2009-01-01

    Previous research stresses the importance of seriation, classification, and counting abilities that should be assessed in kindergarten, when looking for crucial predictors of mathematical learning disabilities in Grade 1. This study examines (n = 158) two-year-long predictive relationships between children's seriation, classification, procedural…

  17. Students' Coordination of Geometric Reasoning and Measuring Strategies on a Fixed Perimeter Task: Developing Mathematical Understanding of Linear Measurement

    ERIC Educational Resources Information Center

    Barrett, Jeffrey E.; Clements, Douglas H.; Klanderman, David; Pennisi, Sarah-Jean; Polaki, Mokaeane V.

    2006-01-01

    This article examines students' development of levels of understanding for measurement by describing the coordination of geometric reasoning with measurement and numerical strategies. In analyzing the reasoning and argumentation of 38 Grade 2 through Grade 10 students on linear measure tasks, we found support for the application and elaboration of…

  18. Character-marked furniture made from red alder harvested in southeast Alaska: product perspectives from consumers and retailers

    Treesearch

    Matthew Bumgardner; David Nicholls; Valerie Barber

    2009-01-01

    In recent decades. red alder (Alnus rubra Bong.) has become an important Pacific Northwest hardwood in appearance-grade lumber markets, such as exports, furniture, and cabinets. However, red alder generally is a short-lived pioneer species, and small logs can result in proportionally large volumes of lower grade lumber containing numerous visual...

  19. Recent Trends in Japanese Mathematics Textbooks for Elementary Grades: Supporting Teachers to Teach Mathematics through Problem Solving

    ERIC Educational Resources Information Center

    Takahashi, Akihiko

    2016-01-01

    Problem solving has been a major theme in Japanese mathematics curricula for nearly 50 years. Numerous teacher reference books and lesson plans using problem solving have been published since the 1960s. Government-authorized mathematics textbooks for elementary grades, published by six private companies, have had more and more problem solving over…

  20. FAST TRACK COMMUNICATION Multi-component generalizations of the CH equation: geometrical aspects, peakons and numerical examples

    NASA Astrophysics Data System (ADS)

    Holm, D. D.; Ivanov, R. I.

    2010-12-01

    The Lax pair formulation of the two-component Camassa-Holm equation (CH2) is generalized to produce an integrable multi-component family, CH(n, k), of equations with n components and 1 <= |k| <= n velocities. All of the members of the CH(n, k) family show fluid-dynamics properties with coherent solitons following particle characteristics. We determine their Lie-Poisson Hamiltonian structures and give numerical examples of their soliton solution behaviour. We concentrate on the CH(2, k) family with one or two velocities, including the CH(2, -1) equation in the Dym position of the CH2 hierarchy. A brief discussion of the CH(3, 1) system reveals the underlying graded Lie-algebraic structure of the Hamiltonian formulation for CH(n, k) when n >= 3. Fondly recalling our late friend Jerry Marsden.

  1. Science for Iowa Schools, Grades 4-6.

    ERIC Educational Resources Information Center

    Nice, Karl; And Others

    This guide includes four units for use in each of grades 4 through 6. The fourth grade units are entitled Measurement Systems, Classification Systems, Bio-Control Systems, and Hydrologic Systems; the fifth grade units are Chemical Systems, Force Systems, Bio-Systems, and Astro-Systems; and the sixth grade units are Equilibrium Systems,…

  2. Striving for a good standard of maths for potential student nurses.

    PubMed

    Roberts, Sheila; Campbell, Anne

    2017-01-12

    This article explores some of the issues surrounding numerical competence for potential pre-registration children's nursing students, with examples of success and failure, at the University of Hertfordshire. With poor numerical ability causing concern in the UK, and the effect of low competence on patient safety when calculating drug dosages in healthcare, this article considers some of the literature surrounding numerical ability, confidence and anxiety, along with considering whether a 'C' grade at GCSE is a suitable marker for assessing numerical competence before starting a pre-registration nursing programme.

  3. Simethicone to prevent colonic bubbles during CT colonography performed with polyethylene glycol lavage and iohexol tagging: a randomized clinical trial.

    PubMed

    Hong, Gil-Sun; Park, Seong Ho; Kim, Bohyun; Lee, Ju Hee; Kim, Jin Cheon; Yu, Chang Sik; Baek, Seunghee; Lee, Jong Seok; Kim, Hyun Jin

    2015-04-01

    The purpose of this study was to determine whether the occurrence of numerous colonic bubbles during CT colonography (CTC) performed with polyethylene glycol cleansing and oral iohexol fecal/fluid tagging could be prevented by use of simethicone. Adults with suspected colonic neoplasia who had been randomly assigned to control and simethicone intervention groups underwent CTC after cleansing with 4 L of polyethylene glycol, tagging with 50 mL of 350 mg I/mL oral iohexol, and without (control) or with (intervention) oral administration of 200 mg of simethicone. Colonic segments in the control and intervention groups were evaluated for amount of colonic bubbles during CTC. A 6-point grading system was used in which 0 indicated no bubbles and 5 indicated that more than three fourths of the air-distended mucosa was covered with bubbles. The primary endpoint was a per-patient colonic bubble grade, derived as an average of the segmental grades. Eighty adults with suspected colonic neoplasia were randomly assigned to the control (40 patients) and simethicone intervention (40 patients) groups. A total of 659 colonic segments in the control group and 689 segments in the intervention group were evaluated for amount of colonic bubbles during CTC. The per-patient colonic bubble score was significantly lower in the simethicone intervention group than in the control group. The mean score was 0.0±0.1 (SD) versus 1.2±0.8 (p<0.001; 95% CI for the mean difference, -1.4 to -1.0). In the intervention group, 673 (97.7%) segments were grade 0, and 16 (2.3%) were grade 1. In contrast, in the control group, 226 (34.3%) segments were grade 0; 173 (26.3%), grade 1; 175 (26.6%), grade 2; 45 (6.8%), grade 3; 23 (3.5%), grade 4; and 17 (2.6%), grade 5. The colonic bubbles associated with fecal/fluid tagging with iohexol can be successfully prevented by adding simethicone to the colonic preparation.

  4. Primary central chondrosarcoma of long bone, limb girdle and trunk: Analysis of 174 cases by numerical scoring on histology

    PubMed Central

    Nakashima, Yasuaki; Mano, Masayuki; Tomita, Yasuhiko; Nagasaki, Ikumitsu; Kubo, Toshikazu; Araki, Nobuhito; Haga, Hironori; Toguchida, Junya; Ueda, Takafumi; Sakuma, Toshiko; Imahori, Masaya; Morii, Eiichi; Yoshikawa, Hideki; Tsukamoto, Yoshitane; Futani, Hiroyuki; Wakasa, Kenichi; Hoshi, Manabu; Hamada, Shinshichi; Takeshita, Hideyuki; Inoue, Takeshi; Aono, Masanari; Kawabata, Kenji; Murata, Hiroaki; Katsura, Kanade; Urata, Yoji; Ueda, Hideki; Yanagisawa, Akio

    2015-01-01

    The aims of this study were: (i) to elucidate clinicopathological characteristics of pcCHS of long bones (L), limb girdles (LG) and trunk (T) in Japan; (ii) to investigate predictive pathological findings for outcome of pcCHS of L, LG and T, objectively; and (iii) to elucidate a discrepancy of grade between biopsy and resected specimens. Clinicopathological profiles of 174 pcCHS (79 male, 95 female), of L, LG, and T were retrieved. For each case, a numerical score was given to 18 pathological findings. The average age was 50.5 years (15–80 years). Frequently involved sites were femur, humerus, pelvis and rib. The 5‐year and 10‐year disease‐specific survival (DSS) rates [follow‐up: 1–258 months (average 65.5)] were 87.0% and 80.4%, respectively. By Cox hazards analysis on pathological findings, age, sex and location, histologically higher grade and older age were unfavorable predictors, and calcification was a favorable predictor in DSS. The histological grade of resected specimen was higher than that of biopsy in 37.7% (26/69 cases). In conclusion, higher histological grade and older age were predictors for poor, but calcification was for good prognosis. Because there was a discrepancy in grade between biopsy and resected specimens, comprehensive evaluation is necessary before definitive operation for pcCHS. PMID:26126783

  5. Cognitive Predictors of Achievement Growth in Mathematics: A Five Year Longitudinal Study

    PubMed Central

    Geary, David C.

    2011-01-01

    The study's goal was to identify the beginning of first grade quantitative competencies that predict mathematics achievement start point and growth through fifth grade. Measures of number, counting, and arithmetic competencies were administered in early first grade and used to predict mathematics achievement through fifth (n = 177), while controlling for intelligence, working memory, and processing speed. Multilevel models revealed intelligence, processing speed, and the central executive component of working memory predicted achievement or achievement growth in mathematics and, as a contrast domain, word reading. The phonological loop was uniquely predictive of word reading and the visuospatial sketch pad of mathematics. Early fluency in processing and manipulating numerical set size and Arabic numerals, accurate use of sophisticated counting procedures for solving addition problems, and accuracy in making placements on a mathematical number line were uniquely predictive of mathematics achievement. Use of memory-based processes to solve addition problems predicted mathematics and reading achievement but in different ways. The results identify the early quantitative competencies that uniquely contribute to mathematics learning. PMID:21942667

  6. Transcoding abilities in typical and atypical mathematics achievers: the role of working memory and procedural and lexical competencies.

    PubMed

    Moura, Ricardo; Wood, Guilherme; Pinheiro-Chagas, Pedro; Lonnemann, Jan; Krinzinger, Helga; Willmes, Klaus; Haase, Vitor Geraldi

    2013-11-01

    Transcoding between numerical systems is one of the most basic abilities acquired by children during their early school years. One important topic that requires further exploration is how mathematics proficiency can affect number transcoding. The aim of the current study was to investigate transcoding abilities (i.e., reading Arabic numerals and writing dictation) in Brazilian children with and without mathematics difficulties, focusing on different school grades. We observed that children with learning difficulties in mathematics demonstrated lower achievement in number transcoding in both early and middle elementary school. In early elementary school, difficulties were observed in both the basic numerical lexicon and the management of numerical syntax. In middle elementary school, difficulties appeared mainly in the transcoding of more complex numbers. An error analysis revealed that the children with mathematics difficulties struggled mainly with the acquisition of transcoding rules. Although we confirmed the previous evidence on the impact of working memory capacity on number transcoding, we found that it did not fully account for the observed group differences. The results are discussed in the context of a maturational lag in number transcoding ability in children with mathematics difficulties. Copyright © 2013 Elsevier Inc. All rights reserved.

  7. Freddie Fish. A Primary Environmental Study of Basic Numerals, Sets, Ordinals and Shapes.

    ERIC Educational Resources Information Center

    Kraynak, Ola

    This teacher's guide and study guide are an environmental approach to mathematics education in the primary grades. The mathematical studies of the numerals 0-10, ordinals, number sets, and basic shapes - diamond, circle, square, rectangle, and triangle - are developed through the story of Freddie Fish and his search for clean water. The…

  8. Basic Numerical Capacities and Prevalence of Developmental Dyscalculia: The Havana Survey

    ERIC Educational Resources Information Center

    Reigosa-Crespo, Vivian; Valdes-Sosa, Mitchell; Butterworth, Brian; Estevez, Nancy; Rodriguez, Marisol; Santos, Elsa; Torres, Paul; Suarez, Ramon; Lage, Agustin

    2012-01-01

    The association of enumeration and number comparison capacities with arithmetical competence was examined in a large sample of children from 2nd to 9th grades. It was found that efficiency on numerical capacities predicted separately more than 25% of the variance in the individual differences on a timed arithmetical test, and this occurred for…

  9. Numerical and Calculation Abilities in Children with ADHD

    ERIC Educational Resources Information Center

    Colomer, Carla; Re, Anna M.; Miranda, Ana; Lucangeli, Daniela

    2013-01-01

    The aim of this study was to investigate the specific numerical and calculation abilities of 28 children with ADHD without comorbid mathematical learning disabilities (LD), ranging from the 1st to the 5th grade of primary school, and to examine the stability or the development of the arithmetic profile. Our results showed that a high percentage of…

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhang, Ch.; Gao, X. W.; Sladek, J.

    This paper reports our recent research works on crack analysis in continuously non-homogeneous and linear elastic functionally graded materials. A meshless boundary element method is developed for this purpose. Numerical examples are presented and discussed to demonstrate the efficiency and the accuracy of the present numerical method, and to show the effects of the material gradation on the crack-opening-displacements and the stress intensity factors.

  11. Chemistry 30: Grade 12 Diploma Examination = Chimie 30: Examen en vue du diplome 12 annee.

    ERIC Educational Resources Information Center

    Alberta Dept. of Education, Edmonton. Student Evaluation Branch.

    This document, in both French and English versions, is the Chemistry 30 Grade 12 Diploma Examination from Alberta Education. It is a 2.5 hour closed-book examination consisting of 44 multiple-choice and 12 numerical-response questions of equal value that are worth 70% of the examination, and 2 written-response questions of equal value worth 30% of…

  12. Biology 30: Grade 12 Diploma Examination = Biologie 30: Examen en vue du diplome 12 annee.

    ERIC Educational Resources Information Center

    Alberta Dept. of Education, Edmonton. Student Evaluation Branch.

    This document, in both English and French versions, is the Biology 30 Grade 12 Diploma Examination from Alberta Education. It is a 2.5 hour closed-book examination consisting of 48 multiple-choice and 8 numerical-response questions of equal value that are worth 70% of the examination, and 2 written-response questions of equal value worth 30% of…

  13. EDUCATIONAL ATTAINMENT AND ATTITUDES TOWARD SCHOOL AS A FUNCTION OF FEEDBACK IN THE FORM OF TEACHERS' WRITTEN COMMENTS.

    ERIC Educational Resources Information Center

    SWEET, ROGER C.

    RELATIONSHIPS BETWEEN A TEACHER'S WRITTEN COMMENTS ON A TEST AND (1) SUBSEQUENT STUDENT ATTAINMENT AS MEASURED BY TEST PERFORMANCE AND (2) ATTITUDE CHANGE TOWARD 9TH-GRADE ENGLISH, WERE INVESTIGATED. 9 CLASSES (225 STUDENTS) WERE GIVEN 4 TESTS BY THEIR TEACHERS OVER A 6-WEEK PERIOD. TESTS WERE RETURNED WITH NUMERICAL SCORES, LETTER GRADE, AND…

  14. Physics 30: Grade 12 Diploma Examination = Physique 30: Examen en vue du diplome 12 annee.

    ERIC Educational Resources Information Center

    Alberta Dept. of Education, Edmonton. Student Evaluation Branch.

    This document, in both English and French versions, is the Physics 30 Grade 12 Diploma Examination from Alberta Education. It is a 2.5 hour closed-book examination consisting of 37 multiple-choice and 12 numerical-response questions of equal value that are worth 70% of the examination, and 2 written-response questions of equal value worth 30% of…

  15. SCOPE (Standardized Curriculum-Oriented Pupil Evaluation) Mathematics. Test Book Grade Three.

    ERIC Educational Resources Information Center

    Northwest Territories Dept. of Education, Yellowknife. Programs and Evaluation Branch.

    Following instructions provided in the teacher's manual, the SCOPE Mathematics Achievement Test booklet for grade 3 presents 11 mathematical concepts. Testing items include: skip counting by 2's, 5's, and 10's to 100, 3's to 30, and 4's to 40; writing number words to 20; identifying and naming 100's, 10's, and 1's in three-digit numerals; reading…

  16. Processing biobased polymers using plasticizers: Numerical simulations versus experiments

    NASA Astrophysics Data System (ADS)

    Desplentere, Frederik; Cardon, Ludwig; Six, Wim; Erkoç, Mustafa

    2016-03-01

    In polymer processing, the use of biobased products shows lots of possibilities. Considering biobased materials, biodegradability is in most cases the most important issue. Next to this, bio based materials aimed at durable applications, are gaining interest. Within this research, the influence of plasticizers on the processing of the bio based material is investigated. This work is done for an extrusion grade of PLA, Natureworks PLA 2003D. Extrusion through a slit die equipped with pressure sensors is used to compare the experimental pressure values to numerical simulation results. Additional experimental data (temperature and pressure data along the extrusion screw and die are recorded) is generated on a dr. Collin Lab extruder producing a 25mm diameter tube. All these experimental data is used to indicate the appropriate functioning of the numerical simulation tool Virtual Extrusion Laboratory 6.7 for the simulation of both the industrial available extrusion grade PLA and the compound in which 15% of plasticizer is added. Adding the applied plasticizer, resulted in a 40% lower pressure drop over the extrusion die. The combination of different experiments allowed to fit the numerical simulation results closely to the experimental values. Based on this experience, it is shown that numerical simulations also can be used for modified bio based materials if appropriate material and process data are taken into account.

  17. Relationships of nuclear, architectural and International Federation of Gynecology and Obstetrics grading systems in endometrial cancer.

    PubMed

    Toptaş, Tayfun; Peştereli, Elif; Bozkurt, Selen; Erdoğan, Gülgün; Şimşek, Tayup

    2018-03-01

    To examine correlations among nuclear, architectural, and International Federation of Gynecology and Obstetrics (FIGO) grading systems, and their relationships with lymph node (LN) involvement in endometrioid endometrial cancer. Histopathology slides of 135 consecutive patients were reviewed with respect to tumor grade and LN metastasis. Notable nuclear atypia was defined as grade 3 nuclei. FIGO grade was established by raising the architectural grade (AG) by one grade when the tumor was composed of cells with nuclear grade (NG) 3. Correlations between the grading systems were analyzed using Spearman's rank correlation coefficients, and relationships of grading systems with LN involvement were assessed using logistic regression analysis. Correlation analysis revealed a significant and strongly positive relationship between FIGO and architectural grading systems (r=0.885, p=0.001); however, correlations of nuclear grading with the architectural (r=0.535, p=0.165) and FIGO grading systems (r=0.589, p=0.082) were moderate and statistically non-significant. Twenty-five (18.5%) patients had LN metastasis. LN involvement rates differed significantly between tumors with AG 1 and those with AG 2, and tumors with FIGO grade 1 and those with FIGO grade 2. In contrast, although the difference in LN involvement rates failed to reach statistical significance between tumors with NG 1 and those with NG 2, it was significant between NG 2 and NG 3 (p=0.042). Although all three grading systems were associated with LN involvement in univariate analyses, an independent relationship could not be established after adjustment for other confounders in multivariate analysis. Nuclear grading is significantly correlated with neither architectural nor FIGO grading systems. The differences in LN involvement rates in the nuclear grading system reach significance only in the setting of tumor cells with NG 3; however, none of the grading systems was an independent predictor of LN involvement.

  18. High-grade extremity soft tissue sarcomas: factors predictive of local recurrence and its effect on morbidity and mortality.

    PubMed

    Eilber, Fritz C; Rosen, Gerald; Nelson, Scott D; Selch, Michael; Dorey, Frederick; Eckardt, Jeffery; Eilber, Frederick R

    2003-02-01

    To identify patient characteristics associated with the development of local recurrence and the effect of local recurrence on subsequent morbidity and mortality in patients with intermediate- to high-grade extremity soft tissue sarcomas. Numerous studies on extremity soft tissue sarcomas have consistently shown that presentation with locally recurrent disease is associated with the development of subsequent local recurrences and that large tumor size and high histologic grade are significant factors associated with decreased survival. However, the effect of local recurrence on patient survival remains unclear. From 1975 to 1997, 753 patients with intermediate- to high-grade extremity soft tissue sarcomas were treated at UCLA. Treatment outcomes and patient characteristics were analyzed to identify factors associated with both local recurrence and survival. Patients with locally recurrent disease were at a significantly increased risk of developing a subsequent local recurrence. Local recurrence was a morbid event requiring amputation in 38% of the cases. The development of a local recurrence was the most significant factor associated with decreased survival. Once a patient developed a local recurrence, he or she was about three times more likely to die of disease compared to similar patients who had not developed a local recurrence. Local recurrence in patients with intermediate- to high-grade extremity soft tissue sarcomas is associated with the development of subsequent local recurrences, a morbid event decreasing functional outcomes and the most significant factor associated with decreased survival. Although 85% to 90% of patients with high-grade extremity soft tissue sarcomas are treatable with a limb salvage approach, patients who develop a local recurrence need aggressive treatment and should be considered for trials of adjuvant systemic therapy.

  19. Lifestyle and nutritional imbalances associated with Western diseases: causes and consequences of chronic systemic low-grade inflammation in an evolutionary context.

    PubMed

    Ruiz-Núñez, Begoña; Pruimboom, Leo; Dijck-Brouwer, D A Janneke; Muskiet, Frits A J

    2013-07-01

    In this review, we focus on lifestyle changes, especially dietary habits, that are at the basis of chronic systemic low grade inflammation, insulin resistance and Western diseases. Our sensitivity to develop insulin resistance traces back to our rapid brain growth in the past 2.5 million years. An inflammatory reaction jeopardizes the high glucose needs of our brain, causing various adaptations, including insulin resistance, functional reallocation of energy-rich nutrients and changing serum lipoprotein composition. The latter aims at redistribution of lipids, modulation of the immune reaction, and active inhibition of reverse cholesterol transport for damage repair. With the advent of the agricultural and industrial revolutions, we have introduced numerous false inflammatory triggers in our lifestyle, driving us to a state of chronic systemic low grade inflammation that eventually leads to typically Western diseases via an evolutionary conserved interaction between our immune system and metabolism. The underlying triggers are an abnormal dietary composition and microbial flora, insufficient physical activity and sleep, chronic stress and environmental pollution. The disturbance of our inflammatory/anti-inflammatory balance is illustrated by dietary fatty acids and antioxidants. The current decrease in years without chronic disease is rather due to "nurture" than "nature," since less than 5% of the typically Western diseases are primary attributable to genetic factors. Resolution of the conflict between environment and our ancient genome might be the only effective manner for "healthy aging," and to achieve this we might have to return to the lifestyle of the Paleolithic era as translated to the 21st century culture. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. Association between basic numerical abilities and mathematics achievement.

    PubMed

    Sasanguie, Delphine; De Smedt, Bert; Defever, Emmy; Reynvoet, Bert

    2012-06-01

    Various measures have been used to investigate number processing in children, including a number comparison or a number line estimation task. The present study aimed to examine whether and to which extent these different measures of number representation are related to performance on a curriculum-based standardized mathematics achievement test in kindergarteners, first, second, and sixth graders. Children completed a number comparison task and a number line estimation task with a balanced set of symbolic (Arabic digits) and non-symbolic (dot patterns) stimuli. Associations with mathematics achievement were observed for the symbolic measures. Although the association with number line estimation was consistent over grades, the association with number comparison was much stronger in kindergarten compared to the other grades. The current data indicate that a good knowledge of the numerical meaning of Arabic digits is important for children's mathematical development and that particularly the access to the numerical meaning of symbolic digits rather than the representation of number per se is important. © 2011 The British Psychological Society.

  1. Perceptions and attitudes of clinicians in Spain toward clinical practice guidelines and grading systems: a protocol for a qualitative study and a national survey

    PubMed Central

    2010-01-01

    Background Clinical practice guidelines (CPGs) have become a very popular tool for decision making in healthcare. While there is some evidence that CPGs improve outcomes, there are numerous factors that influence their acceptability and use by healthcare providers. While evidence of clinicians' knowledge, perceptions and attitudes toward CPGs is extensive, results are still disperse and not conclusive. Our study will evaluate these issues in a large and representative sample of clinicians in Spain. Methods/Design A mixed-method design combining qualitative and quantitative research techniques will evaluate general practitioners (GPs) and hospital-based specialists in Spain with the objective of exploring attitudes and perceptions about CPGs and evidence grading systems. The project will consist of two phases: during the first phase, group discussions will be carried out to gain insight into perceptions and attitudes of the participants, and during the second phase, this information will be completed by means of a survey, reaching a greater number of clinicians. We will explore these issues in GPs and hospital-based practitioners, with or without previous experience in guideline development. Discussion Our study will identify and gain insight into the perceived problems and barriers of Spanish practitioners in relation to guideline knowledge and use. The study will also explore beliefs and attitudes of clinicians towards CPGs and evidence grading systems used to rate the quality of the evidence and the strength of recommendations. Our results will provide guidance to healthcare researchers and healthcare decision makers to improve the use of guidelines in Spain and elsewhere. PMID:21129195

  2. [The WHO/ISUP grading system for renal carcinoma].

    PubMed

    Moch, H

    2016-07-01

    Histological tumor grading is an accepted prognostic parameter of renal cell carcinoma (RCC). In 2012, the International Society of Urologic Pathologists (ISUP) proposed a novel grading system for RCC, mainly based on the evaluation of nucleoli: grade 1 tumors have nucleoli that are inconspicuous and basophilic at ×400 magnification; grade 2 tumors have nucleoli that are clearly visible at ×400 magnification and eosinophilic; grade 3 tumors have clearly visible nucleoli at ×100 magnification; and grade 4 tumors have extreme pleomorphism or rhabdoid and/or sarcomatoid morphology. This grading system was validated for clear cell renal cell carcinoma and papillary renal cell carcinoma. At the same time, the ISUP proposed not grading chromophobe renal cell carcinomas according to this system. At a consensus conference in Zurich the World Health Organization (WHO) recommended the ISUP grading system; thus, the WHO/ISUP grading system is now going to be implemented internationally. The ISUP/WHO grading system has not been validated as a prognostic parameter for other tumor subtypes, but can be used for descriptive purposes.

  3. A Study of the Effect of the Implementation of the Plus/Minus Grading System on Graduate Student Grades.

    ERIC Educational Resources Information Center

    Malone, Bobby G.; Nelson, Jacquelyn S.; Nelson, C. Van

    The implementation of a plus/minus system of grading to replace the traditional A through F grading system for graduate students was studied at a midsize Midwestern university. Decimal equivalents were established to enable the computation of grade point averages (GPAs) that reflected the dispersion of grades through the plus/minus system. A…

  4. Influence of Controlled Viscous Dissipation on Propagation of Strongly Nonlinear Waves in Steel-Based Phononic Crystals

    NASA Astrophysics Data System (ADS)

    Herbold, Eric

    2005-07-01

    Strongly nonlinear phononic crystals were assembled from chains of stainless steel spheres with diameter 4.78 mm. Propagation of solitary waves and splitting of initial pulse into train of solitary waves excited by the impact of piston was investigated in different viscous media in experiments and in numerical calculations. Oil of various grades was used to introduce controlled dissipation into the system. Preliminary results indicate that splitting of the initial pulse into the train of solitary waves was dramatically influenced by viscosity. This work was supported by NSF (Grant No. DCMS03013220).

  5. The effect of grading the atomic number at resistive guide element interface on magnetic collimation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Alraddadi, R. A. B.; Woolsey, N. C.; Robinson, A. P. L.

    2016-07-15

    Using 3 dimensional numerical simulations, this paper shows that grading the atomic number and thus the resistivity at the interface between an embedded high atomic number guide element and a lower atomic number substrate enhances the growth of a resistive magnetic field. This can lead to a large integrated magnetic flux density, which is fundamental to confining higher energy fast electrons. This results in significant improvements in both magnetic collimation and fast-electron-temperature uniformity across the guiding. The graded interface target provides a method for resistive guiding that is tolerant to laser pointing.

  6. 2013 strategic petroleum reserve big hill well integrity grading report.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lord, David L.; Roberts, Barry L.; Lord, Anna C. Snider

    2014-02-01

    This report summarizes the work performed in developing a framework for the prioritization of cavern access wells for remediation and monitoring at the Big Hill Strategic Petroleum Reserve site. This framework was then applied to all 28 wells at the Big Hill site with each well receiving a grade for remediation and monitoring. Numerous factors affecting well integrity were incorporated into the grading framework including casing survey results, cavern pressure history, results from geomechanical simulations, and site geologic factors. The framework was developed in a way as to be applicable to all four of the Strategic Petroleum Reserve sites.

  7. The value of different Risser grading systems in determining growth maturity of girls with adolescent idiopathic scoliosis.

    PubMed

    Wang, Weijun; Zhen, Xin; Sun, Xu; Zhu, Zezhang; Zhu, Feng; Lam, T P; Cheng, Jack C Y; Qiu, Yong

    2012-01-01

    A grading system for ossification of the iliac apophysis (Risser sign) was developed for skeletal maturity assessment in the United States (US) then adopted with modifications in France (Fr) and other countries. Despite the same name, these systems have important differences. With the aim to analyzing the difference between US and Fr Risser grading systems in determining the growth maturity of girls with adolescent idiopathic scoliosis (AIS), Fifty-three AIS girls undergoing posterior spinal correction with autogenous bone graft were recruited. The Risser grades were recorded for the non-dominant side iliac crest apophysis according to the US and Fr grading systems. Growth activity was determined by standard histologic grades (HGs) on iliac crest cartilage. As a result, Kappa statistics showed poor agreement between two grading systems. The US system showed higher correlation with HGs compared to Fr system by Spearman correlation analysis. It was also found that growth cessation could be determined by Risser grade 5 of US system or Risser grade 4 of Fr system. Furthermore, by employing Receiver Operating Characteristic (ROC) curve analysis, it was found that the Risser grade 4-5 of US system with two years after menarche could be used in determining growth cessation with the highest sensitivity, specificity and accuracy. Hence it was concluded that the US Risser grading system was better in determining maturity of girls with AIS than Fr Risser grading system. By combining years since menarche, the accuracy of Risser grades in determining growth cessation could be enhanced, and the time of weaning from a brace could be advanced.

  8. Numerical modeling of the load effect on PZT-induced guided wave for load compensation of damage detection

    NASA Astrophysics Data System (ADS)

    Sun, Hu; Zhang, Aijia; Wang, Yishou; Qing, Xinlin P.

    2017-04-01

    Guided wave-based structural health monitoring (SHM) has been given considerable attention and widely studied for large-scale aircraft structures. Nevertheless, it is difficult to apply SHM systems on board or online, for which one of the most serious reasons is the environmental influence. Load is one fact that affects not only the host structure, in which guided wave propagates, but also the PZT, by which guided wave is transmitted and received. In this paper, numerical analysis using finite element method is used to study the load effect on guided wave acquired by PZT. The static loads with different grades are considered to analyze its effect on guided wave signals that PZT transmits and receives. Based on the variation trend of guided waves versus load, a load compensation method is developed to eliminate effects of load in the process of damage detection. The probabilistic reconstruction algorithm based on the signal variation of transmitter-receiver path is employed to identify the damage. Numerical tests is conducted to verify the feasibility and effectiveness of the given method.

  9. Correlations among Five Demographic Variables and the Performance of Selected Jamaican 11th-Graders on Some Numerical Problems on Energy

    ERIC Educational Resources Information Center

    Emepue, Nicholas; Soyibo, Kola

    2009-01-01

    This study was designed to assess whether the level of performance of selected Jamaican 11th-grade physics students on some numerical problems on the energy concept was satisfactory and if there were significant differences in their performance linked to their gender, socioeconomic background (SEB), school location, English language and…

  10. Strain rate sensitivity of the tensile strength of two silicon carbides: experimental evidence and micromechanical modelling

    NASA Astrophysics Data System (ADS)

    Zinszner, Jean-Luc; Erzar, Benjamin; Forquin, Pascal

    2017-01-01

    Ceramic materials are commonly used to design multi-layer armour systems thanks to their favourable physical and mechanical properties. However, during an impact event, fragmentation of the ceramic plate inevitably occurs due to its inherent brittleness under tensile loading. Consequently, an accurate model of the fragmentation process is necessary in order to achieve an optimum design for a desired armour configuration. In this work, shockless spalling tests have been performed on two silicon carbide grades at strain rates ranging from 103 to 104 s-1 using a high-pulsed power generator. These spalling tests characterize the tensile strength strain rate sensitivity of each ceramic grade. The microstructural properties of the ceramics appear to play an important role on the strain rate sensitivity and on the dynamic tensile strength. Moreover, this experimental configuration allows for recovering damaged, but unbroken specimens, giving unique insight on the fragmentation process initiated in the ceramics. All the collected data have been compared with corresponding results of numerical simulations performed using the Denoual-Forquin-Hild anisotropic damage model. Good agreement is observed between numerical simulations and experimental data in terms of free surface velocity, size and location of the damaged zones along with crack density in these damaged zones. This article is part of the themed issue 'Experimental testing and modelling of brittle materials at high strain rates'.

  11. Strain rate sensitivity of the tensile strength of two silicon carbides: experimental evidence and micromechanical modelling.

    PubMed

    Zinszner, Jean-Luc; Erzar, Benjamin; Forquin, Pascal

    2017-01-28

    Ceramic materials are commonly used to design multi-layer armour systems thanks to their favourable physical and mechanical properties. However, during an impact event, fragmentation of the ceramic plate inevitably occurs due to its inherent brittleness under tensile loading. Consequently, an accurate model of the fragmentation process is necessary in order to achieve an optimum design for a desired armour configuration. In this work, shockless spalling tests have been performed on two silicon carbide grades at strain rates ranging from 10 3 to 10 4  s -1 using a high-pulsed power generator. These spalling tests characterize the tensile strength strain rate sensitivity of each ceramic grade. The microstructural properties of the ceramics appear to play an important role on the strain rate sensitivity and on the dynamic tensile strength. Moreover, this experimental configuration allows for recovering damaged, but unbroken specimens, giving unique insight on the fragmentation process initiated in the ceramics. All the collected data have been compared with corresponding results of numerical simulations performed using the Denoual-Forquin-Hild anisotropic damage model. Good agreement is observed between numerical simulations and experimental data in terms of free surface velocity, size and location of the damaged zones along with crack density in these damaged zones.This article is part of the themed issue 'Experimental testing and modelling of brittle materials at high strain rates'. © 2016 The Author(s).

  12. Exact Analysis of the Flow and Heat Transfer of the SA-TiO2 Non-Newtonian Nanofluid Between Two Coaxial Cylinders Through a Porous Medium

    NASA Astrophysics Data System (ADS)

    Almazmumy, Mariam; Ebaid, Abdelhalim

    2017-08-01

    In this article, the flow and heat transfer of a non-Newtonian nanofluid between two coaxial cylinders through a porous medium has been investigated. The velocity, temperature, and nanoparticles concentration of the present mathematical model are governed by a system of nonlinear ordinary differential equations. The objective of this article is to obtain new exact solutions for the temperature and the nanoparticles concentration and, therefore, compare them with the previous approximate results in the literature. Moreover, the velocity equation has been numerically solved. The effects of the pressure gradient, thermophoresis, third-grade, Brownian motion, and porosity parameters on the included phenomena have been discussed through several tables and plots. It is found that the velocity profile is increased by increasing the pressure gradient parameter, thermophoresis parameter (slightly), third-grade parameter, and Brownian motion parameter (slightly); however, it decreases with an increase in the porosity parameter and viscosity power index. In addition, the temperature and the nanoparticles concentration reduce with the strengthen of the Brownian motion parameter, while they increase by increasing the thermophoresis parameter. Furthermore, the numerical solution and the physical interpretation in the literature for the same problem have been validated with the current exact analysis, where many remarkable differences and errors have been concluded. Therefore, the suggested analysis may be recommended with high trust for similar problems.

  13. Strain rate sensitivity of the tensile strength of two silicon carbides: experimental evidence and micromechanical modelling

    PubMed Central

    Erzar, Benjamin

    2017-01-01

    Ceramic materials are commonly used to design multi-layer armour systems thanks to their favourable physical and mechanical properties. However, during an impact event, fragmentation of the ceramic plate inevitably occurs due to its inherent brittleness under tensile loading. Consequently, an accurate model of the fragmentation process is necessary in order to achieve an optimum design for a desired armour configuration. In this work, shockless spalling tests have been performed on two silicon carbide grades at strain rates ranging from 103 to 104 s−1 using a high-pulsed power generator. These spalling tests characterize the tensile strength strain rate sensitivity of each ceramic grade. The microstructural properties of the ceramics appear to play an important role on the strain rate sensitivity and on the dynamic tensile strength. Moreover, this experimental configuration allows for recovering damaged, but unbroken specimens, giving unique insight on the fragmentation process initiated in the ceramics. All the collected data have been compared with corresponding results of numerical simulations performed using the Denoual–Forquin–Hild anisotropic damage model. Good agreement is observed between numerical simulations and experimental data in terms of free surface velocity, size and location of the damaged zones along with crack density in these damaged zones. This article is part of the themed issue ‘Experimental testing and modelling of brittle materials at high strain rates’. PMID:27956504

  14. Math Achievement, Numerical Processing, and Executive Functions in Girls with Turner Syndrome: Do Girls with Turner Syndrome Have Math Learning Disability?

    ERIC Educational Resources Information Center

    Mazzocco, Michele M. M.; Hanich, Laurie B.

    2010-01-01

    Turner syndrome is a common genetic disorder associated with select deficits in executive functions, working memory and mathematics. In Study 1, we examined growth trajectories of skills in these areas, from grades 1 to 6, among girls with or without Turner syndrome. Rates of growth and performance levels at 6th grade, on an untimed math…

  15. Shape of wear particles found in human knee joints and their relationship to osteoarthritis.

    PubMed

    Kuster, M S; Podsiadlo, P; Stachowiak, G W

    1998-09-01

    To analyse and compare the shape of wear particles found in healthy and osteoarthritic human knee joints for monitoring the progress of osteoarthritis, the long-term prognosis and to evaluate therapeutic regimens. Joint particles from seven patients with normal cartilage in all compartments of the knee joint, 12 patients with fibrillation of less than half the cartilage thickness (grade 1), seven patients with fibrillation of more than half the cartilage thickness (grade 2) and four patients with erosions down to bone (grade 3) were analysed. A total of 565 particles were extracted from synovial fluid samples by ferrography and analysed in a scanning electron microscope. A number of numerical descriptors, i.e. boundary fractal dimension, shape factor, convexity and elongation, were calculated for each particle image and correlated to the degree of osteoarthritis using non-parametric tests. Experiments demonstrated that there were significant differences between the numerical descriptors calculated for wear particles from healthy and osteoarthritic knee joints (P < 0.01), suggesting that the particle shape can be used as an indicator of the joint condition. In particular, the fractal dimension of the particle boundary was shown to correlate directly with the degree of osteoarthritis. Numerical analysis of the shape of wear particles found in human knee joints may provide a reliable means for the assessment of cartilage repair after surgical or conservative treatment of osteoarthritis.

  16. Primary central chondrosarcoma of long bone, limb girdle and trunk: Analysis of 174 cases by numerical scoring on histology.

    PubMed

    Konishi, Eiichi; Nakashima, Yasuaki; Mano, Masayuki; Tomita, Yasuhiko; Nagasaki, Ikumitsu; Kubo, Toshikazu; Araki, Nobuhito; Haga, Hironori; Toguchida, Junya; Ueda, Takafumi; Sakuma, Toshiko; Imahori, Masaya; Morii, Eiichi; Yoshikawa, Hideki; Tsukamoto, Yoshitane; Futani, Hiroyuki; Wakasa, Kenichi; Hoshi, Manabu; Hamada, Shinshichi; Takeshita, Hideyuki; Inoue, Takeshi; Aono, Masanari; Kawabata, Kenji; Murata, Hiroaki; Katsura, Kanade; Urata, Yoji; Ueda, Hideki; Yanagisawa, Akio

    2015-09-01

    The aims of this study were: (i) to elucidate clinicopathological characteristics of pcCHS of long bones (L), limb girdles (LG) and trunk (T) in Japan; (ii) to investigate predictive pathological findings for outcome of pcCHS of L, LG and T, objectively; and (iii) to elucidate a discrepancy of grade between biopsy and resected specimens. Clinicopathological profiles of 174 pcCHS (79 male, 95 female), of L, LG, and T were retrieved. For each case, a numerical score was given to 18 pathological findings. The average age was 50.5 years (15-80 years). Frequently involved sites were femur, humerus, pelvis and rib. The 5-year and 10-year disease-specific survival (DSS) rates [follow-up: 1-258 months (average 65.5)] were 87.0% and 80.4%, respectively. By Cox hazards analysis on pathological findings, age, sex and location, histologically higher grade and older age were unfavorable predictors, and calcification was a favorable predictor in DSS. The histological grade of resected specimen was higher than that of biopsy in 37.7% (26/69 cases). In conclusion, higher histological grade and older age were predictors for poor, but calcification was for good prognosis. Because there was a discrepancy in grade between biopsy and resected specimens, comprehensive evaluation is necessary before definitive operation for pcCHS. © 2015 The Authors. Pathology International published by Japanese Society of Pathology and Wiley Publishing Asia Pty Ltd.

  17. Use of a 2-tier histologic grading system for canine cutaneous mast cell tumors on cytology specimens.

    PubMed

    Hergt, Franziska; von Bomhard, Wolf; Kent, Michael S; Hirschberger, Johannes

    2016-09-01

    Mast cell tumors (MCT) represent the most common malignant skin tumor in the dog. Diagnosis of an MCT can be achieved through cytologic examination of a fine-needle aspirate. However, the grade of the tumor is an important prognostic marker and currently requires histologic assessment. Recently a 2-tier histologic grading system based on nuclear features including number of mitoses, multinucleated cells, bizarre nuclei, and karyomegaly was proposed. The aim of this study was to assess if the cytomorphologic criteria proposed in the 2-tier histologic grading system are applicable to cytology specimens. A total of 141 MCT specimens reported as grade I, II, or III according to the Patnaik system with both histologic specimens and fine-needle aspirates available were histologically and cytologically reevaluated in a retrospective study. According to the 2-tier grading system, 38 cases were diagnosed histologically as high-grade and 103 as low-grade MCT. Cytologic grading resulted in 36 high-grade and 105 low-grade tumors. Agreement between histologic and cytologic grading based on the 2-tier grading system was achieved in 133 cases (sensitivity 86.8%, specificity 97.1%, kappa value 0.853), but 5 high-grade tumors on histology were classified as low-grade on cytology. Cytologic grading of MCT in the dog is helpful for initial assessment. However, the reliability of cytology using the 2-tier grading system is considered inadequate at this point. Prospective studies including clinical outcome should be pursued to further determine diagnostic accuracy of cytologic mast cell grading. © 2016 American Society for Veterinary Clinical Pathology.

  18. Contribution a l'auscultation des chaussees mixtes par methodes GPR et electrique

    NASA Astrophysics Data System (ADS)

    Kaouane, Carole

    Quebec's infrastructures are ageing. A reliable, quick and economical assessment of the state of urban roads would help to plan civil engineering. This M.Sc. thesis aims to investigate and develop the potential of Ground Penetrating Radar (GPR) and electrical methods to assess pavement condition subject to wetting, freezing and drying cycles. The objectives are to display defects and estimate water content in the materials used for the mixed pavement construction; these consist in layers of asphalt (top), concrete (middle) and grade and sub-grade (bottom). Prior studies showed a valuable potential of joint application of GPR and electrical resistivity to assess mixed pavement condition. These studies were mainly based on numerical modeling and some site tests using both methods. It was concluded that a better evaluation of the potential of the coupled methods would come from the assessment of physical properties and validation from geotechnical evidences. At first, we characterized the context. Structural defects and water content implied modification of physical properties of road materials. After running numerical modeling, we carried out an experiment in one of the streets in Montreal (Canada) where pavement needed complete rehabilitation. GPR surveys were carried out before the pavement was destroyed and removed, and subsequently a resistivity imaging was carried out on the subgrade layer. We also sampled blocks of asphalt and concrete along the street from the demolition rubble in order to study their physical properties in the lab. Soil samples were taken from trenches to measure water content. The grade and sub-grade were mainly a mix of clayey-silt and gravel, as the embedding ground is grey clay. We measured the complex dielectric constants of asphalt and concrete in the range 50 MHz-900 MHz with a recently developed dielectric probe sampling a volume of 30 cm3. Resistivity measurements were also performed on large cores of asphalt and concrete using an inhouse system. Measurements were carried out on dry and wet samples, which provided a range of values encompassing the climatic conditions for the whole year. Finally the physical property and geotechnical data were used as input to numerical modeling and the modeled responses compared to the survey data. The predicted data fit nicely with the observed data. This work aims to provide further information for a better calibration of geophysical devices in pavement condition assessment. Moreover, it gives a wide range of information, which could become a base for further and more specific works.

  19. Reliability of injury grading systems for patients with blunt splenic trauma.

    PubMed

    Olthof, D C; van der Vlies, C H; Scheerder, M J; de Haan, R J; Beenen, L F M; Goslings, J C; van Delden, O M

    2014-01-01

    The most widely used grading system for blunt splenic injury is the American Association for the Surgery of Trauma (AAST) organ injury scale. In 2007 a new grading system was developed. This 'Baltimore CT grading system' is superior to the AAST classification system in predicting the need for angiography and embolization or surgery. The objective of this study was to assess inter- and intraobserver reliability between radiologists in classifying splenic injury according to both grading systems. CT scans of 83 patients with blunt splenic injury admitted between 1998 and 2008 to an academic Level 1 trauma centre were retrospectively reviewed. Inter and intrarater reliability were expressed in Cohen's or weighted Kappa values. Overall weighted interobserver Kappa coefficients for the AAST and 'Baltimore CT grading system' were respectively substantial (kappa=0.80) and almost perfect (kappa=0.85). Average weighted intraobserver Kappa's values were in the 'almost perfect' range (AAST: kappa=0.91, 'Baltimore CT grading system': kappa=0.81). The present study shows that overall the inter- and intraobserver reliability for grading splenic injury according to the AAST grading system and 'Baltimore CT grading system' are equally high. Because of the integration of vascular injury, the 'Baltimore CT grading system' supports clinical decision making. We therefore recommend use of this system in the classification of splenic injury. Copyright © 2012 Elsevier Ltd. All rights reserved.

  20. Alternative Grading Systems. The Practitioner, Vol. III, No. 3.

    ERIC Educational Resources Information Center

    De Leonibus, Nancy; Thomson, Scott

    After examining some of the pros and cons of traditional grading, the demands colleges make on grading practices, and the responses of people interested in grading, a number of examples of operating alternative systems are given. The alternatives include a dual (pass/withdraw grading in some courses, traditional grading in others) system, a…

  1. Impaired acuity of the approximate number system underlies mathematical learning disability (dyscalculia)

    PubMed Central

    Mazzocco, Michèle M. M.; Feigenson, Lisa; Halberda, Justin

    2015-01-01

    Many children have significant mathematical learning disabilities (MLD, or dyscalculia) despite adequate schooling. We hypothesize that MLD partly results from a deficiency in the Approximate Number System (ANS) that supports nonverbal numerical representations across species and throughout development. Here we show that ninth grade students with MLD have significantly poorer ANS precision than students in all other mathematics achievement groups (low-, typically-, and high-achieving), as measured by psychophysical assessments of ANS acuity (w) and of the mappings between ANS representations and number words (cv). This relationship persists even when controlling for domain-general abilities. Furthermore, this ANS precision does not differentiate low- from typically-achieving students, suggesting an ANS deficit that is specific to MLD. PMID:21679173

  2. Recent Advances in Bathymetric Surveying of Continental Shelf Regions Using Autonomous Vehicles

    NASA Astrophysics Data System (ADS)

    Holland, K. T.; Calantoni, J.; Slocum, D.

    2016-02-01

    Obtaining bathymetric observations within the continental shelf in areas closer to the shore is often time consuming and dangerous, especially when uncharted shoals and rocks present safety concerns to survey ships and launches. However, surveys in these regions are critically important to numerical simulation of oceanographic processes, as bathymetry serves as the bottom boundary condition in operational forecasting models. We will present recent progress in bathymetric surveying using both traditional vessels retrofitted for autonomous operations and relatively inexpensive, small team deployable, Autonomous Underwater Vehicles (AUV). Both systems include either high-resolution multibeam echo sounders or interferometric sidescan sonar sensors with integrated inertial navigation system capabilities consistent with present commercial-grade survey operations. The advantages and limitations of these two configurations employing both unmanned and autonomous strategies are compared using results from several recent survey operations. We will demonstrate how sensor data collected from unmanned platforms can augment or even replace traditional data collection technologies. Oceanographic observations (e.g., sound speed, temperature and currents) collected simultaneously with bathymetry using autonomous technologies provide additional opportunities for advanced data assimilation in numerical forecasts. Discussion focuses on our vision for unmanned and autonomous systems working in conjunction with manned or in-situ systems to optimally and simultaneously collect data in environmentally hostile or difficult to reach areas.

  3. Validation of a two-tier grading system in an unselected, consecutive cohort of serous ovarian cancer patients.

    PubMed

    Battista, Marco Johannes; Cotarelo, Cristina; Almstedt, Katrin; Heimes, Anne-Sophie; Makris, Georgios-Marios; Weyer, Veronika; Schmidt, Marcus

    2016-09-01

    New insights into the carcinogenesis of ovarian cancer (OC) lead to the definition of low-grade and high-grade serous OC. In this study, we validated the MD Anderson Cancer Center (MDACC) two-tier grading system and compared it with the traditional three-tier grading system as suggested by the International Federation of Gynecology and Obstetrics (FIGO). Consecutive patients with serous OC were enrolled. These two grading systems were assessed independently from each other. Kaplan-Meier estimates and Cox-regression analyses were performed to validate and compare their prognostic impact. 143 consecutive patients entered the study. According to the Kaplan-Meier estimates, the MDACC grading system (p = 0.001) predicted the progression free survival (PFS) more precisely than the FIGO system (p = 0.025). The MDACC grading system (p = 0.008) but not the FIGO system (p = 0.329) showed a statistically significant difference in terms of disease specific survival (DSS). Multivariable Cox-regression analyses revealed an independent prognostic impact of the MDACC grading system but not of the FIGO system for PFS (HR 1.570; 95 % CI 1.007-2.449; p = 0.047, and HR 0.712; 95 % CI 0.476-1.066; p = 0.099, respectively). Concerning DSS, the two-tier grading system but not the FIGO system showed a prognostic impact in a univariable Cox-regression analysis (HR 2.152; 95 % CI 1.207-3.835; p = 0.009, and HR 1.258; 95 % CI 0.801-1.975; p = 0.319, respectively). We were able to validate the MDACC grading system in serous OC. Moreover, this grading system was stronger associated with survival than the FIGO system.

  4. Pathways to fraction learning: Numerical abilities mediate the relation between early cognitive competencies and later fraction knowledge.

    PubMed

    Ye, Ai; Resnick, Ilyse; Hansen, Nicole; Rodrigues, Jessica; Rinne, Luke; Jordan, Nancy C

    2016-12-01

    The current study investigated the mediating role of number-related skills in the developmental relationship between early cognitive competencies and later fraction knowledge using structural equation modeling. Fifth-grade numerical skills (i.e., whole number line estimation, non-symbolic proportional reasoning, multiplication, and long division skills) mapped onto two distinct factors: magnitude reasoning and calculation. Controlling for participants' (N=536) demographic characteristics, these two factors fully mediated relationships between third-grade general cognitive competencies (attentive behavior, verbal and nonverbal intellectual abilities, and working memory) and sixth-grade fraction knowledge (concepts and procedures combined). However, specific developmental pathways differed by type of fraction knowledge. Magnitude reasoning ability fully mediated paths from all four cognitive competencies to knowledge of fraction concepts, whereas calculation ability fully mediated paths from attentive behavior and verbal ability to knowledge of fraction procedures (all with medium to large effect sizes). These findings suggest that there are partly overlapping, yet distinct, developmental pathways from cognitive competencies to general fraction knowledge, fraction concepts, and fraction procedures. Copyright © 2016 Elsevier Inc. All rights reserved.

  5. Las Matematicas: Lenguaje Universal. Nivel 1: Numeros y Numeracion (Mathematics: A Universal Language. Level 1: Numbers and Numeration).

    ERIC Educational Resources Information Center

    Dissemination and Assessment Center for Bilingual Education, Austin, TX.

    This is one of a series of student booklets designed for use in a bilingual mathematics program in grades 6-8. The general format is to present each page in both Spanish and English. The mathematical topics in this booklet include graphing on a number line, place value, using exponents, flow charts, and Roman numerals. (MK)

  6. Efficient High-Fidelity, Geometrically Exact, Multiphysics Structural Models

    DTIC Science & Technology

    2011-10-14

    fuctionally graded core. International Journal for Numerical Methods in Engineering, 68:940– 966, 2006. 7F. Shang, Z. Wang, and Z. Li. Analysis of...normal deformable plate theory and MLPG method with radial basis fuctions . Composite Structures, 80:539– 552, 2007. 17W. Zhen and W. Chen. A higher-order...functionally graded plates by using higher-order shear and normal deformable plate theory and MLPG method with radial basis fuctions . Composite Structures, 80

  7. Engineering photonic nanojet by a graded-index micro-cuboid

    NASA Astrophysics Data System (ADS)

    Liu, Cheng-Yang; Yen, Tzu-Ping; Minin, Oleg V.; Minin, Igor V.

    2018-04-01

    In the present paper the basic characteristics (length, peak intensity, and full-width half-maximum) of nanojets formed in the vicinity of dielectric core-shell cuboids with different types of index grading are investigated by finite-difference time domain method. The latitudinal and longitudinal sizes of a nanojet and its peak intensity depending on the optical contrast variation of cuboids core-shells are numerically investigated. It has been shown that it is possible to control and elongate the nanojet abnormally. It also was shown that graded cuboid with dimensions of 4 × 4 × 4 wavelength may has FWHM of a jet less than uniform cuboid with dimensions of 1 × 1 × 1 wavelength. At wavelength of 600 nm graded index cuboid with dimensions of 4 × 4 × 4 wavelength and index grading = 2 allow to form photonic jet with FWHM about 232 nm or 0.39 wavelength.

  8. Predicted sedimentary record of reflected bores

    USGS Publications Warehouse

    Higman, B.; Gelfenbaum, G.; Lynett, P.; Moore, A.; Jaffe, B.

    2007-01-01

    Where a steep slope blocks an inrushing tsunami, the tsunami commonly reverses direction as a reflected bore. A simple method for relating vertical and horizontal variation in sediment size to output from numerical models of depth-averaged tsunami flow yields predictions about the sedimentary record of reflected bores: 1. Near the reflector, a abrupt slowing of the flow as the reflected bore passes is recorded by a normally graded layer that drapes preexisting topography. 2. At intermediate distances from the reflector, the deposit consists of a single normally graded bed deposited preferentially in depressions, possibly including a sharp fine-over-coarse contact. This contact records a brief period of erosion as the front of the reflected bore passes. 3. Far seaward of the reflector, grading in the deposit includes two distinct normally graded beds deposited preferentially in depressions separated by an erosional unconformity. The second normally graded bed records the reflected bore.

  9. The Role of the Insulin/IGF System in Cancer: Lessons Learned from Clinical Trials and the Energy Balance-Cancer Link

    PubMed Central

    Bowers, Laura W.; Rossi, Emily L.; O’Flanagan, Ciara H.; deGraffenried, Linda A.; Hursting, Stephen D.

    2015-01-01

    Numerous epidemiological and pre-clinical studies have demonstrated that the insulin/insulin-like growth factor (IGF) system plays a key role in the development and progression of several types of cancer. Insulin/IGF signaling, in cooperation with chronic low-grade inflammation, is also an important contributor to the cancer-promoting effects of obesity. However, clinical trials for drugs targeting different components of this system have produced largely disappointing results, possibly due to the lack of predictive biomarker use and problems with the design of combination therapy regimens. With careful attention to the identification of likely patient responders and optimal drug combinations, the outcome of future trials may be improved. Given that insulin/IGF signaling is known to contribute to obesity-associated cancer, further investigation regarding the efficacy of drugs targeting this system and its downstream effectors in the obese patient population is warranted. PMID:26029167

  10. A Machine Vision System for Automatically Grading Hardwood Lumber - (Proceedings)

    Treesearch

    Richard W. Conners; Tai-Hoon Cho; Chong T. Ng; Thomas H. Drayer; Joe G. Tront; Philip A. Araman; Robert L. Brisbon

    1990-01-01

    Any automatic system for grading hardwood lumber can conceptually be divided into two components. One of these is a machine vision system for locating and identifying grading defects. The other is an automatic grading program that accepts as input the output of the machine vision system and, based on these data, determines the grade of a board. The progress that has...

  11. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Johnson, C.; Burnett, M.; Goodman, C.

    A survey of currency flaw severity was carried out using 300 banknotes and 37 judges. Each judge assigned each note to one of five flaw severity categories. These categories correspond to severity grades of 1 to 5 with 1 equivalent to ''always accepted'' and 5 ''never accepted.'' An average flaw severity grade for each note was obtained by taking the mean of the severity grades assigned to that note by the 37 judges. Thus, each note has a single numerical real-number flaw grade between 1 and 5. Mathematical modeling of the currency flaw survey results is continuing with some verymore » promising initial results. Our present model handles common excess ink and missing ink flaw types quite well. We plan to extend the model to ink level, mash, setoff and blanket impression flaw types.« less

  12. A Machine Vision System for Automatically Grading Hardwood Lumber - (Industrial Metrology)

    Treesearch

    Richard W. Conners; Tai-Hoon Cho; Chong T. Ng; Thomas T. Drayer; Philip A. Araman; Robert L. Brisbon

    1992-01-01

    Any automatic system for grading hardwood lumber can conceptually be divided into two components. One of these is a machine vision system for locating and identifying grading defects. The other is an automatic grading program that accepts as input the output of the machine vision system and, based on these data, determines the grade of a board. The progress that has...

  13. Innovative Use of a Classroom Response System During Physics Lab

    NASA Astrophysics Data System (ADS)

    Walgren, Jay

    2011-01-01

    More and more physics instructors are making use of personal/classroom response systems or "clickers." The use of clickers to engage students with multiple-choice questions during lecture and available instructor resources for clickers have been well documented in this journal.1-4 Newer-generation clickers, which I refer to as classroom response systems (CRS), have evolved to accept numeric answers (such as 9.81) instead of just single "multiple-choice" entries (Fig. 1). This advancement is available from most major clicker companies and allows for a greater variety of engaging questions during lecture. In addition, these new "numeric ready" clickers are marketed to be used for student assessments. During a test or quiz, students' answers are entered into their clicker instead of on paper or Scantron® and immediately absorbed by wireless connection into a computer for grading and analysis. I recognize the usefulness and benefit these new-generation CRSs provide for many instructors. However, I do not use my CRS in either of the aforementioned activities. Instead, I use it in an unconventional way. I use the CRS to electronically capture students' lab data as they are performing a physics lab (Fig. 2). I set up the clickers as if I were going to use them for a test, but instead of entering answers to a test, my students enter lab data as they collect it. In this paper I discuss my use of a classroom response system during physics laboratory and three benefits that result: 1) Students are encouraged to "take ownership of" and "have integrity with" their physics lab data. 2) Students' measuring and unit conversion deficiencies are identified immediately during the lab. 3) The process of grading students' labs is simplified because the results of each student's lab calculations can be pre-calculated for the instructor using a spreadsheet. My use of clickers during lab can be implemented with most clicker systems available to instructors today. The CRS I use is the eInstruction's® Classroom Performance System™ (CPS™).5 (Fig. 1)

  14. [Prostate cancer. Part 2: Review of the various tumor grading systems over the years 1966-2015 and future perspectives of the new grading of the International Society of Urological Pathology (ISUP)].

    PubMed

    Helpap, B; Bubendorf, L; Kristiansen, G

    2016-02-01

    The continued development of methods in needle biopsies and radical prostatectomy for treatment of prostate cancer has given special emphasis to the question of the prognostic relevance of the various systems of grading. The classical purely histological grading system of Gleason has been modified several times in the past decades and cleared the way for a new grading system by the prognostic grading of Epstein. Assessment of the old and also modified combined histological and cytological grading of Mostofi, the World health Organization (WHO) and the urologic-pathological working group of prostate cancer in connection with the Gleason grading (combined Gleason-Helpap grading), has led to considerably improved rates of concordance between biopsy and radical prostatectomy and to improved estimations of prognosis beside its contribution to the development of a more practicable grading system for clinical use.

  15. Inferior turbinate classification system, grades 1 to 4: development and validation study.

    PubMed

    Camacho, Macario; Zaghi, Soroush; Certal, Victor; Abdullatif, Jose; Means, Casey; Acevedo, Jason; Liu, Stanley; Brietzke, Scott E; Kushida, Clete A; Capasso, Robson

    2015-02-01

    To develop a validated inferior turbinate grading scale. Development and validation study. Phase 1 development (alpha test) consisted of a proposal of 10 different inferior turbinate grading scales (>1,000 clinic patients). Phase 2 validation (beta test) utilized 10 providers grading 27 standardized endoscopic photos of inferior turbinates using two different classification systems. Phase 3 validation (pilot study) consisted of 100 live consecutive clinic patients (n = 200 inferior turbinates) who were each prospectively graded by 18 different combinations of two independent raters, and grading was repeated by each of the same two raters, two separate times for each patient. In the development phase, 25% (grades 1-4) and 33% (grades 1-4) were the most useful systems. In the validation phase, the 25% classification system was found to be the best balance between potential clinical utility and ability to grade; the photo grading demonstrated a Cohen's kappa (κ) = 0.4671 ± 0.0082 (moderate inter-rater agreement). Live-patient grading with the 25% classification system demonstrated an overall inter-rater reliability of 71.5% (95% confidence interval [CI]: 64.8-77.3), with overall substantial agreement (κ = 0.704 ± 0.028). Intrarater reliability was 91.5% (95% CI: 88.7-94.3). Distribution for the 200 inferior turbinates was as follows: 25% quartile = grade 1, 50% quartile (median) = grade 2, 75% quartile = grade 3, and 90% quartile = grade 4. Mean turbinate size was 2.22 (95% CI: 2.07-2.34; standard deviation 1.02). Categorical κ was as follows: grade 1, 0.8541 ± 0.0289; grade 2, 0.7310 ± 0.0289; grade 3, 0.6997 ± 0.0289, and grade 4, 0.7760 ± 0.0289. The 25% (grades 1-4) inferior turbinate classification system is a validated grading scale with high intrarater and inter-rater reliability. This system can facilitate future research by tracking the effect of interventions on inferior turbinates. 2c. © 2014 The American Laryngological, Rhinological and Otological Society, Inc.

  16. International Spring and Summer Festivals. Projects and Patterns for Holiday Gifts, Greetings, Ornaments, Decorations, and Classroom Displays. A Good Apple Seasonal Idea/Activity Book for Grades 1-6.

    ERIC Educational Resources Information Center

    Barr, Marilynn G.

    This seasonal idea/activity book for grades 1-6 features interesting facts on the origins of traditions and customs of spring and summer festivals from around the world. There are numerous hands-on art activities, a map of each country or continent of the activity's origin, and a brief explanation of each tradition. Areas and countries of the…

  17. A review on exudates detection methods for diabetic retinopathy.

    PubMed

    Joshi, Shilpa; Karule, P T

    2018-01-01

    The presence of exudates on the retina is the most characteristic symptom of diabetic retinopathy. As exudates are among early clinical signs of DR, their detection would be an essential asset to the mass screening task and serve as an important step towards automatic grading and monitoring of the disease. Reliable identification and classification of exudates are of inherent interest in an automated diabetic retinopathy screening system. Here we review the numerous early studies that used for automatic exudates detection with the aim of providing decision support in addition to reducing the workload of an ophthalmologist. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  18. Electronic Medical Record-Based Radiation Oncology Toxicity Recording Instrument Aids Benchmarking and Quality Improvement in the Clinic.

    PubMed

    Albuquerque, Kevin; Rodgers, Kellie; Spangler, Ann; Rahimi, Asal; Willett, DuWayne

    2018-03-01

    The on-treatment visit (OTV) for radiation oncology is essential for patient management. Radiation toxicities recorded during the OTV may be inconsistent because of the use of free text and the lack of treatment site-specific templates. We developed a radiation oncology toxicity recording instrument (ROTOX) in a health system electronic medical record (EMR). Our aims were to assess improvement in documentation of toxicities and to develop clinic toxicity benchmarks. A ROTOX that was based on National Cancer Institute Common Terminology Criteria for Adverse Events (version 4.0) with flow-sheet functionality was developed in the EMR. Improvement in documentation was assessed at various time intervals. High-grade toxicities (ie, grade ≥ 3 by CTCAE) by site were audited to develop benchmarks and to track nursing and physician actions taken in response to these. A random sample of OTV notes from each clinic physician before ROTOX implementation was reviewed and assigned a numerical document quality score (DQS) that was based on completeness and comprehensiveness of toxicity grading. The mean DQS improved from an initial level of 41% to 99% (of the maximum possible DQS) when resampled at 6 months post-ROTOX. This high-level DQS was maintained 3 years after ROTOX implementation at 96% of the maximum. For months 7 to 9 after implementation (during a 3-month period), toxicity grading was recorded in 4,443 OTVs for 698 unique patients; 107 episodes of high-grade toxicity were identified during this period, and toxicity-specific intervention was documented in 95%. An EMR-based ROTOX enables consistent recording of treatment toxicity. In a uniform sample of patients, local population toxicity benchmarks can be developed, and clinic response can be tracked.

  19. Prospective evaluation of Ki-67 system in histological grading of soft tissue sarcomas in the Japan Clinical Oncology Group Study JCOG0304.

    PubMed

    Tanaka, Kazuhiro; Hasegawa, Tadashi; Nojima, Takayuki; Oda, Yoshinao; Mizusawa, Junki; Fukuda, Haruhiko; Iwamoto, Yukihide

    2016-04-18

    The correct clinical staging of soft tissue sarcomas (STS) is critical for the selection of treatments. The staging system consists of histological grade of the tumors and French Federation of Cancer Center (FNCLCC) system based on mitotic count is widely used for the grading. In this study, we compared the validity and usefulness of Ki-67 grading system with FNCLCC system in JCOG0304 trial which investigated the efficacy and safety of perioperative chemotherapy with doxorubicin and ifosfamide for STS. All 70 eligible patients with STS in the extremities treated by perioperative chemotherapy in JCOG0304 were analyzed. Univariate and multivariate Cox regression analyses were conducted to investigate an influence on overall survival. The reproducibility of Ki-67 grading system in the histological grading of STS was higher than FNCLCC system (κ = 0.54 [95 % CI 0.39-0.71], and 0.46 [0.32-0.62], respectively). Although FNCLCC grade was not associated with overall survival (OS) in univariate analysis (HR 2.80 [0.74-10.55], p = 0.13), Ki-67 grading system had a tendency to associate with OS in univariate analysis (HR 4.12 [0.89-19.09], p = 0.07) and multivariate analysis with backward elimination (HR 3.51 [0.75-16.36], p = 0.11). This is the first report demonstrating the efficacy of Ki-67 grading system for the patients with STS in the prospective trial. The results indicate that Ki-67 grading system might be useful for the evaluation of histological grade of STS.

  20. Comprehensive study of numerical anisotropy and dispersion in 3-D TLM meshes

    NASA Astrophysics Data System (ADS)

    Berini, Pierre; Wu, Ke

    1995-05-01

    This paper presents a comprehensive analysis of the numerical anisotropy and dispersion of 3-D TLM meshes constructed using several generalized symmetrical condensed TLM nodes. The dispersion analysis is performed in isotropic lossless, isotropic lossy and anisotropic lossless media and yields a comparison of the simulation accuracy for the different TLM nodes. The effect of mesh grading on the numerical dispersion is also determined. The results compare meshes constructed with Johns' symmetrical condensed node (SCN), two hybrid symmetrical condensed nodes (HSCN) and two frequency domain symmetrical condensed nodes (FDSCN). It has been found that under certain circumstances, the time domain nodes may introduce numerical anisotropy when modelling isotropic media.

  1. Varieties of quantity estimation in children.

    PubMed

    Sella, Francesco; Berteletti, Ilaria; Lucangeli, Daniela; Zorzi, Marco

    2015-06-01

    In the number-to-position task, with increasing age and numerical expertise, children's pattern of estimates shifts from a biased (nonlinear) to a formal (linear) mapping. This widely replicated finding concerns symbolic numbers, whereas less is known about other types of quantity estimation. In Experiment 1, Preschool, Grade 1, and Grade 3 children were asked to map continuous quantities, discrete nonsymbolic quantities (numerosities), and symbolic (Arabic) numbers onto a visual line. Numerical quantity was matched for the symbolic and discrete nonsymbolic conditions, whereas cumulative surface area was matched for the continuous and discrete quantity conditions. Crucially, in the discrete condition children's estimation could rely either on the cumulative area or numerosity. All children showed a linear mapping for continuous quantities, whereas a developmental shift from a logarithmic to a linear mapping was observed for both nonsymbolic and symbolic numerical quantities. Analyses on individual estimates suggested the presence of two distinct strategies in estimating discrete nonsymbolic quantities: one based on numerosity and the other based on spatial extent. In Experiment 2, a non-spatial continuous quantity (shades of gray) and new discrete nonsymbolic conditions were added to the set used in Experiment 1. Results confirmed the linear patterns for the continuous tasks, as well as the presence of a subset of children relying on numerosity for the discrete nonsymbolic numerosity conditions despite the availability of continuous visual cues. Overall, our findings demonstrate that estimation of numerical and non-numerical quantities is based on different processing strategies and follow different developmental trajectories. (c) 2015 APA, all rights reserved).

  2. The Cognitive Predictors of Computational Skill with Whole versus Rational Numbers: An Exploratory Study.

    PubMed

    Seethaler, Pamela M; Fuchs, Lynn S; Star, Jon R; Bryant, Joan

    2011-10-01

    The purpose of the present study was to explore the 3(rd)-grade cognitive predictors of 5th-grade computational skill with rational numbers and how those are similar to and different from the cognitive predictors of whole-number computational skill. Students (n = 688) were assessed on incoming whole-number calculation skill, language, nonverbal reasoning, concept formation, processing speed, and working memory in the fall of 3(rd) grade. Students were followed longitudinally and assessed on calculation skill with whole numbers and with rational numbers in the spring of 5(th) grade. The unique predictors of skill with whole-number computation were incoming whole-number calculation skill, nonverbal reasoning, concept formation, and working memory (numerical executive control). In addition to these cognitive abilities, language emerged as a unique predictor of rational-number computational skill.

  3. The Cognitive Predictors of Computational Skill with Whole versus Rational Numbers: An Exploratory Study

    PubMed Central

    Seethaler, Pamela M.; Fuchs, Lynn S.; Star, Jon R.; Bryant, Joan

    2011-01-01

    The purpose of the present study was to explore the 3rd-grade cognitive predictors of 5th-grade computational skill with rational numbers and how those are similar to and different from the cognitive predictors of whole-number computational skill. Students (n = 688) were assessed on incoming whole-number calculation skill, language, nonverbal reasoning, concept formation, processing speed, and working memory in the fall of 3rd grade. Students were followed longitudinally and assessed on calculation skill with whole numbers and with rational numbers in the spring of 5th grade. The unique predictors of skill with whole-number computation were incoming whole-number calculation skill, nonverbal reasoning, concept formation, and working memory (numerical executive control). In addition to these cognitive abilities, language emerged as a unique predictor of rational-number computational skill. PMID:21966180

  4. Computer program grade 2 for the design and analysis of heat-pipe wicks

    NASA Technical Reports Server (NTRS)

    Eninger, J. E.; Edwards, D. K.

    1976-01-01

    This user's manual describes the revised version of the computer program GRADE(1), which designs and analyzes heat pipes with graded porosity fibrous slab wicks. The revisions are: (1) automatic calculation of the minimum condenser-end stress that will not result in an excess-liquid puddle or a liquid slug in the vapor space; (2) numerical solution of the equations describing flow in the circumferential grooves to assess the burnout criterion; (3) calculation of the contribution of excess liquid in fillets and puddles to the heat-transport; (4) calculation of the effect of partial saturation on the wick performance; and (5) calculation of the effect of vapor flow, which includes viscousinertial interactions.

  5. Developmental dissociation in the neural responses to simple multiplication and subtraction problems

    PubMed Central

    Prado, Jérôme; Mutreja, Rachna; Booth, James R.

    2014-01-01

    Mastering single-digit arithmetic during school years is commonly thought to depend upon an increasing reliance on verbally memorized facts. An alternative model, however, posits that fluency in single-digit arithmetic might also be achieved via the increasing use of efficient calculation procedures. To test between these hypotheses, we used a cross-sectional design to measure the neural activity associated with single-digit subtraction and multiplication in 34 children from 2nd to 7th grade. The neural correlates of language and numerical processing were also identified in each child via localizer scans. Although multiplication and subtraction were undistinguishable in terms of behavior, we found a striking developmental dissociation in their neural correlates. First, we observed grade-related increases of activity for multiplication, but not for subtraction, in a language-related region of the left temporal cortex. Second, we found grade-related increases of activity for subtraction, but not for multiplication, in a region of the right parietal cortex involved in the procedural manipulation of numerical quantities. The present results suggest that fluency in simple arithmetic in children may be achieved by both increasing reliance on verbal retrieval and by greater use of efficient quantity-based procedures, depending on the operation. PMID:25089323

  6. Calculating corner singularities by boundary integral equations.

    PubMed

    Shi, Hualiang; Lu, Ya Yan; Du, Qiang

    2017-06-01

    Accurate numerical solutions for electromagnetic fields near sharp corners and edges are important for nanophotonics applications that rely on strong near fields to enhance light-matter interactions. For cylindrical structures, the singularity exponents of electromagnetic fields near sharp edges can be solved analytically, but in general the actual fields can only be calculated numerically. In this paper, we use a boundary integral equation method to compute electromagnetic fields near sharp edges, and construct the leading terms in asymptotic expansions based on numerical solutions. Our integral equations are formulated for rescaled unknown functions to avoid unbounded field components, and are discretized with a graded mesh and properly chosen quadrature schemes. The numerically found singularity exponents agree well with the exact values in all the test cases presented here, indicating that the numerical solutions are accurate.

  7. Systematic analysis underlying the quality of the scientific evidence and conflicts of interest in interventional medicine subspecialty guidelines.

    PubMed

    Feuerstein, Joseph D; Akbari, Mona; Gifford, Anne E; Hurley, Christine M; Leffler, Daniel A; Sheth, Sunil G; Cheifetz, Adam S

    2014-01-01

    To determine the validity of guidelines published by interventional medical societies. We reviewed the interventional medicine subspecialty society websites of the American Association for Bronchology and Interventional Pulmonology (AABIP), American Society of Diagnostic and Interventional Nephrology (ASDIN), American Society for Gastrointestinal Endoscopy (ASGE), and Society for Cardiovascular Angiography and Interventions (SCAI) as of November 15, 2012, for published interventional guidelines. The study was performed between November 15, 2012, and January 1, 2013. The AABIP did not publish guidelines, so American Thoracic Society and American College of Chest Physicians guidelines were reviewed. All the guidelines were reviewed for graded levels of evidence, methods used to grade the evidence, and disclosures of conflicts of interest (COIs). Of 153 interventional guidelines evaluated, 4 were duplicates. Forty-six percent of guidelines (69 of 149) graded the quality of evidence using 7 different methods. The ASGE graded 71% of guidelines (46 of 65) compared with 29% (23 of 78) by the SCAI and 0 by the ASDIN (n=4) and the pulmonary societies (n=2). Of the 3425 recommendations reviewed, 11% (n=364) were supported by level A, 42% (n=1432) by level B, and 48% (n=1629) by level C. The mean age of the guidelines was 5.2 years. Additionally, 62% of the guidelines (92 of 149) failed to comment on COIs; when disclosed, 91% of guidelines (52 of 57) reported COIs. In total, 1827 COIs were reported by 45% of the authors (317 of 697), averaging 5.8 COIs per author. Most of the interventional guidelines failed to grade the evidence. When present, most guidelines used lower-quality evidence. Furthermore, most guidelines failed to disclose COIs. When commented on, numerous COIs were present. Future guidelines should clearly state the quality of evidence, use a standard grading system, be transparent regarding potential biases, and provide frequent updates. Copyright © 2014 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

  8. Swedish PE Teachers Struggle with Assessment in a Criterion-Referenced Grading System

    ERIC Educational Resources Information Center

    Svennberg, Lena; Meckbach, Jane; Redelius, Karin

    2018-01-01

    In the field of education, the international trend is to turn to criterion-referenced grading in the hope of achieving accountable and consistent grades. Despite a national criterion-referenced grading system emphasising knowledge as the only base for grading, Swedish physical education (PE) grades have been shown to value non-knowledge factors,…

  9. Refining the quantitative pathway of the Pathways to Mathematics model.

    PubMed

    Sowinski, Carla; LeFevre, Jo-Anne; Skwarchuk, Sheri-Lynn; Kamawar, Deepthi; Bisanz, Jeffrey; Smith-Chant, Brenda

    2015-03-01

    In the current study, we adopted the Pathways to Mathematics model of LeFevre et al. (2010). In this model, there are three cognitive domains--labeled as the quantitative, linguistic, and working memory pathways--that make unique contributions to children's mathematical development. We attempted to refine the quantitative pathway by combining children's (N=141 in Grades 2 and 3) subitizing, counting, and symbolic magnitude comparison skills using principal components analysis. The quantitative pathway was examined in relation to dependent numerical measures (backward counting, arithmetic fluency, calculation, and number system knowledge) and a dependent reading measure, while simultaneously accounting for linguistic and working memory skills. Analyses controlled for processing speed, parental education, and gender. We hypothesized that the quantitative, linguistic, and working memory pathways would account for unique variance in the numerical outcomes; this was the case for backward counting and arithmetic fluency. However, only the quantitative and linguistic pathways (not working memory) accounted for unique variance in calculation and number system knowledge. Not surprisingly, only the linguistic pathway accounted for unique variance in the reading measure. These findings suggest that the relative contributions of quantitative, linguistic, and working memory skills vary depending on the specific cognitive task. Copyright © 2014 Elsevier Inc. All rights reserved.

  10. Reliability and Validity of the Arthroscopic International Cartilage Repair Society Classification System: Correlation With Histological Assessment of Depth.

    PubMed

    Dwyer, Tim; Martin, C Ryan; Kendra, Rita; Sermer, Corey; Chahal, Jaskarndip; Ogilvie-Harris, Darrell; Whelan, Daniel; Murnaghan, Lucas; Nauth, Aaron; Theodoropoulos, John

    2017-06-01

    To determine the interobserver reliability of the International Cartilage Repair Society (ICRS) grading system of chondral lesions in cadavers, to determine the intraobserver reliability of the ICRS grading system comparing arthroscopy and video assessment, and to compare the arthroscopic ICRS grading system with histological grading of lesion depth. Eighteen lesions in 5 cadaveric knee specimens were arthroscopically graded by 7 fellowship-trained arthroscopic surgeons using the ICRS classification system. The arthroscopic video of each lesion was sent to the surgeons 6 weeks later for repeat grading and determination of intraobserver reliability. Lesions were biopsied, and the depth of the cartilage lesion was assessed. Reliability was calculated using intraclass correlations. The interobserver reliability was 0.67 (95% confidence interval, 0.5-0.89) for the arthroscopic grading, and the intraobserver reliability with the video grading was 0.8 (95% confidence interval, 0.67-0.9). A high correlation was seen between the arthroscopic grading of depth and the histological grading of depth (0.91); on average, surgeons graded lesions using arthroscopy a mean of 0.37 (range, 0-0.86) deeper than the histological grade. The arthroscopic ICRS classification system has good interobserver and intraobserver reliability. A high correlation with histological assessment of depth provides evidence of validity for this classification system. As cartilage lesions are treated on the basis of the arthroscopic ICRS classification, it is important to ascertain the reliability and validity of this method. Copyright © 2016 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.

  11. Nanoscale Graphene Disk: A Natural Functionally Graded Material–How is Fourier’s Law Violated along Radius Direction of 2D Disk

    PubMed Central

    Yang, Nuo; Hu, Shiqian; Ma, Dengke; Lu, Tingyu; Li, Baowen

    2015-01-01

    In this Paper, we investigate numerically and analytically the thermal conductivity of nanoscale graphene disks (NGDs), and discussed the possibility to realize functionally graded material (FGM) with only one material, NGDs. Different from previous studies on divergence/non-diffusive of thermal conductivity in nano-structures with different size, we found a novel non-homogeneous (graded) thermal conductivity along the radius direction in a single nano-disk structure. We found that, instead of a constant value, the NGD has a graded thermal conductivity along the radius direction. That is, Fourier’s law of heat conduction is not valid in two dimensional graphene disk structures Moreover, we show the dependent of NGDs’ thermal conductivity on radius and temperature. Our study might inspire experimentalists to develop NGD based versatile FGMs, improve understanding of the heat removal of hot spots on chips, and enhance thermoelectric energy conversion efficiency by two dimensional disk with a graded thermal conductivity. PMID:26443206

  12. Nanoscale Graphene Disk: A Natural Functionally Graded Material-How is Fourier's Law Violated along Radius Direction of 2D Disk.

    PubMed

    Yang, Nuo; Hu, Shiqian; Ma, Dengke; Lu, Tingyu; Li, Baowen

    2015-10-07

    In this Paper, we investigate numerically and analytically the thermal conductivity of nanoscale graphene disks (NGDs), and discussed the possibility to realize functionally graded material (FGM) with only one material, NGDs. Different from previous studies on divergence/non-diffusive of thermal conductivity in nano-structures with different size, we found a novel non-homogeneous (graded) thermal conductivity along the radius direction in a single nano-disk structure. We found that, instead of a constant value, the NGD has a graded thermal conductivity along the radius direction. That is, Fourier's law of heat conduction is not valid in two dimensional graphene disk structures Moreover, we show the dependent of NGDs' thermal conductivity on radius and temperature. Our study might inspire experimentalists to develop NGD based versatile FGMs, improve understanding of the heat removal of hot spots on chips, and enhance thermoelectric energy conversion efficiency by two dimensional disk with a graded thermal conductivity.

  13. Post-traumatic subtalar osteoarthritis: which grading system should we use?

    PubMed

    de Muinck Keizer, Robert-Jan O; Backes, Manouk; Dingemans, Siem A; Goslings, J Carel; Schepers, Tim

    2016-09-01

    To assess and compare post-traumatic osteoarthritis following intra-articular calcaneal fractures, one must have a reliable grading system that consistently grades the post-traumatic changes of the joint. A reliable grading system aids in the communication between treating physicians and improves the interpretation of research. To date, there is no consensus on what grading system to use in the evaluation of post-traumatic subtalar osteoarthritis. The objective of this study was to determine and compare the inter- and intra-rater reliability of two grading systems for post-traumatic subtalar osteoarthritis. Four observers evaluated 50 calcaneal fractures at least one year after trauma on conventional oblique lateral, internally and externally rotated views, and graded post-traumatic subtalar osteoarthritis using the Kellgren and Lawrence Grading Scale (KLGS) and the Paley Grading System (PGS). Inter- and intra-rater reliability were calculated and compared. The inter-rater reliability showed an intra-class correlation (ICC) of 0.54 (95 % CI 0.40-0.67) for the KLGS and an ICC of 0.41 (95 % CI 0.26 - 0.57) for the PGS. This difference was not statistically significant. The intra-rater reliability showed a mean weighted kappa of 0.62 for both the KLGS and the PGS. There is no statistically significant difference in reliability between the Kellgren and Lawrence Grading System (KLGS) and the Paley Grading System (PGS). The PGS allows for an easy two-step approach making it easy for everyday clinical purposes. For research purposes however, the more detailed and widely used KLGS seems preferable.

  14. Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

    ClinicalTrials.gov

    2013-05-01

    Childhood Atypical Teratoid/Rhabdoid Tumor; Childhood Central Nervous System Choriocarcinoma; Childhood Central Nervous System Embryonal Tumor; Childhood Central Nervous System Germinoma; Childhood Central Nervous System Mixed Germ Cell Tumor; Childhood Central Nervous System Teratoma; Childhood Central Nervous System Yolk Sac Tumor; Childhood Choroid Plexus Tumor; Childhood Craniopharyngioma; Childhood Ependymoblastoma; Childhood Grade I Meningioma; Childhood Grade II Meningioma; Childhood Grade III Meningioma; Childhood High-grade Cerebellar Astrocytoma; Childhood High-grade Cerebral Astrocytoma; Childhood Infratentorial Ependymoma; Childhood Low-grade Cerebellar Astrocytoma; Childhood Low-grade Cerebral Astrocytoma; Childhood Medulloepithelioma; Childhood Mixed Glioma; Childhood Oligodendroglioma; Childhood Supratentorial Ependymoma; Extra-adrenal Paraganglioma; Recurrent Childhood Brain Stem Glioma; Recurrent Childhood Central Nervous System Embryonal Tumor; Recurrent Childhood Cerebellar Astrocytoma; Recurrent Childhood Cerebral Astrocytoma; Recurrent Childhood Ependymoma; Recurrent Childhood Medulloblastoma; Recurrent Childhood Pineoblastoma; Recurrent Childhood Spinal Cord Neoplasm; Recurrent Childhood Subependymal Giant Cell Astrocytoma; Recurrent Childhood Supratentorial Primitive Neuroectodermal Tumor; Recurrent Childhood Visual Pathway and Hypothalamic Glioma

  15. Buckling of graded coatings: A continuum model

    NASA Astrophysics Data System (ADS)

    Chiu, Tz-Cheng

    2000-12-01

    Requirements for the protection of hot section components in many high temperature applications such as earth-to-orbit winged planes and advanced turbine systems have led to the application of thermal barrier coatings (TBCs) that utilize ceramic coatings on metal substrates. An alternative concept to homogeneous ceramic coatings is the functionally graded materials (FGM) in which the composition of the coating is intentionally graded to improve the bonding strength and to reduce the magnitude of the residual and thermal stresses. A widely observed failure mode in such layered systems is known to be interface cracking that leads to spallation fracture. In most cases, the final stage of the failure process for a thin coating appears to be due to buckling instability under thermally or mechanically induced compressive stress. The objective of this study is to develop a solution to the buckling instability problem by using continuum elasticity rather than a structural mechanics approach. The emphasis in the solution will be on the investigation of the effect of material inhomogeneity in graded coatings on the instability load, the postbuckling behavior, and fracture mechanics parameters such as the stress intensity factors and strain energy release rate. In this analysis, a nonlinear continuum theory is employed to examine the interface crack problem. The analytical solution of the instability problem permits the study of the effect of material inhomogeneity upon the inception of buckling and establishes benchmark results for the numerical solutions of related problems. To study the postbuckling behavior and to calculate the stress intensity factors and strain energy release rate a geometrically nonlinear finite element procedure with enriched crack-tip element is developed. Both plane strain and axisymmetric interface crack problems in TBCs with either homogeneous or graded coating are then considered by using the finite element procedure. It is assumed that the applied load is a uniform temperature drop. Comparison of the results with that obtained from the plate approximation shows that because of the higher constraints the plate theory predicts greater instability strains and lower strain energy release rates. It is also observed that compared with a homogeneous coating the graded coating gives lower strain energy release rate because of the lower thermal residual stress and higher bending stiffness. (Abstract shortened by UMI.)

  16. Developmental gains in visuospatial memory predict gains in mathematics achievement.

    PubMed

    Li, Yaoran; Geary, David C

    2013-01-01

    Visuospatial competencies are related to performance in mathematical domains in adulthood, but are not consistently related to mathematics achievement in children. We confirmed the latter for first graders and demonstrated that children who show above average first-to-fifth grade gains in visuospatial memory have an advantage over other children in mathematics. The study involved the assessment of the mathematics and reading achievement of 177 children in kindergarten to fifth grade, inclusive, and their working memory capacity and processing speed in first and fifth grade. Intelligence was assessed in first grade and their second to fourth grade teachers reported on their in-class attentive behavior. Developmental gains in visuospatial memory span (d = 2.4) were larger than gains in the capacity of the central executive (d = 1.6) that in turn were larger than gains in phonological memory span (d = 1.1). First to fifth grade gains in visuospatial memory and in speed of numeral processing predicted end of fifth grade mathematics achievement, as did first grade central executive scores, intelligence, and in-class attentive behavior. The results suggest there are important individual differences in the rate of growth of visuospatial memory during childhood and that these differences become increasingly important for mathematics learning.

  17. Developmental Gains in Visuospatial Memory Predict Gains in Mathematics Achievement

    PubMed Central

    Li, Yaoran; Geary, David C.

    2013-01-01

    Visuospatial competencies are related to performance in mathematical domains in adulthood, but are not consistently related to mathematics achievement in children. We confirmed the latter for first graders and demonstrated that children who show above average first-to-fifth grade gains in visuospatial memory have an advantage over other children in mathematics. The study involved the assessment of the mathematics and reading achievement of 177 children in kindergarten to fifth grade, inclusive, and their working memory capacity and processing speed in first and fifth grade. Intelligence was assessed in first grade and their second to fourth grade teachers reported on their in-class attentive behavior. Developmental gains in visuospatial memory span (d = 2.4) were larger than gains in the capacity of the central executive (d = 1.6) that in turn were larger than gains in phonological memory span (d = 1.1). First to fifth grade gains in visuospatial memory and in speed of numeral processing predicted end of fifth grade mathematics achievement, as did first grade central executive scores, intelligence, and in-class attentive behavior. The results suggest there are important individual differences in the rate of growth of visuospatial memory during childhood and that these differences become increasingly important for mathematics learning. PMID:23936154

  18. Graft-versus-Host Disease of the Gut: A Histologic Activity Grading System and Validation.

    PubMed

    Myerson, David; Steinbach, Gideon; Gooley, Ted A; Shulman, Howard M

    2017-09-01

    The pathologic interpretation of gut biopsies in hematopoietic cell transplant recipients to assess graft-versus-host disease (GVHD) is well accepted and supplements clinical and endoscopic findings. However, the histologic activity grading of GVHD is controversial, with attempts to predict prognosis or response to treatment largely unsuccessful. GVHD is being diagnosed earlier in its course, raising the possibility that the pathologic grading system can be profitably modified. We developed a histologic activity grading system designed to replace the commonly used modified Lerner grading systems. Our system stratifies the low-level Lerner grade I category into 4 activity grade categories, based on the average frequency of apoptotic cells. The results are expressed as ordinal categories: GVHD of minimal, mild, moderate, severe histologic activity, or severe histologic activity with destruction (activity grades 1 to 5). In a retrospective study, we studied 87 consecutive cases with 201 post-transplantation specimens (median, 48 days; range, 18 to 1479 days) of stomach, duodenum, and colorectum, which had been activity graded at the time of the original diagnosis. Most of the biopsies diagnosed as GVHD were low grade-minimal (11%) or mild (71%) histologic activity. We hypothesized that the higher activity grades would be associated with more therapeutic intervention. The odds of increased therapy in the combined all-site specimens were increased as activity grade increased (odds ratio, 2.9 [95% confidence interval {CI}, 1.9 to 4.5]; P = < .0001). Thus, our grading system was validated. To investigate whether the activity grade was associated with therapy within the formerly undivided Lerner grade I category, the analysis was restricted to these 174 all-site specimens. The validation result was similar (odds ratio, 3.1 [95% CI, 1.3 to 7.2]; P = .009). This result interestingly suggests that there is useful information hidden in the Lerner grade I category, which could potentially guide immediately actionable treatment decisions. This histologic activity grade system has been in use at our institution for over 2 years with good acceptance. Copyright © 2017 The American Society for Blood and Marrow Transplantation. Published by Elsevier Inc. All rights reserved.

  19. 78 FR 60331 - Privacy Act of 1974: System of Records

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-01

    ... on Position Classification Appeals, Job Grading Appeals, Retained Grade or Pay Appeals, Fair Labor..., Job Grading Appeals, Retained Grade or Pay Appeals, Fair Labor Standard Act (FLSA) Claims and... appeal or a job grading appeal with the U.S. Office of Personnel Management, Merit System Accountability...

  20. Gleason grading system

    MedlinePlus

    ... medlineplus.gov/ency/patientinstructions/000920.htm Gleason grading system To use the sharing features on this page, ... score of between 5 and 7. Gleason Grading System Sometimes, it can be hard to predict how ...

  1. Accordion complication grading predicts short-term outcome after right colectomy.

    PubMed

    Klos, Coen L; Safar, Bashar; Hunt, Steven R; Wise, Paul E; Birnbaum, Elisa H; Mutch, Matthew G; Fleshman, James W; Dharmarajan, Sekhar

    2014-08-01

    The Accordion severity grading system is a novel system to score the severity of postoperative complications in a standardized fashion. This study aims to demonstrate the validity of the Accordion system in colorectal surgery by correlating severity grades with short-term outcomes after right colectomy for colon cancer. This is a retrospective cohort review of patients who underwent right colectomy for cancer between January 1, 2002, and January 31, 2007, at a single tertiary care referral center. Complications were categorized according to the Accordion severity grading system: grades 1 (mild), 2 (moderate), 3-5 (severe), and 6 (death). Outcome measures were hospital stay, 30-d readmission rate and 1-y survival. Correlation between Accordion grades and outcome measures is reflected by Spearman rho (ρ). One-year survival was obtained per Kaplan-Meier method and compared by logrank test for trend. Significance was set at P ≤ 0.05. Overall, 235 patients underwent right colectomy for cancer of which 122 (51.9%) had complications. In total, 52 (43%) had an Accordion grade 1 complication; 44 (36%) grade 2; four (3%) grade 3; 11 (9%) grade 4; seven (6%) grade 5; and four (3%) grade 6. There was significant correlation between Accordion grades and hospital stay (ρ = 0.495, P < 0.001) and 30-d readmission rate (ρ = 0.335, P < 0.001). There was a significant downward trend in 1-y survival as complication severity by Accordion grade increased (P = 0.02). The Accordion grading system is a useful tool to estimate short-term outcomes after right colectomy for cancer. High-grade Accordion complications are associated with longer hospital stay and increased risk of readmission and mortality. Published by Elsevier Inc.

  2. Arithmetic and algebraic problem solving and resource allocation: the distinct impact of fluid and numerical intelligence.

    PubMed

    Dix, Annika; van der Meer, Elke

    2015-04-01

    This study investigates cognitive resource allocation dependent on fluid and numerical intelligence in arithmetic/algebraic tasks varying in difficulty. Sixty-six 11th grade students participated in a mathematical verification paradigm, while pupil dilation as a measure of resource allocation was collected. Students with high fluid intelligence solved the tasks faster and more accurately than those with average fluid intelligence, as did students with high compared to average numerical intelligence. However, fluid intelligence sped up response times only in students with average but not high numerical intelligence. Further, high fluid but not numerical intelligence led to greater task-related pupil dilation. We assume that fluid intelligence serves as a domain-general resource that helps to tackle problems for which domain-specific knowledge (numerical intelligence) is missing. The allocation of this resource can be measured by pupil dilation. Copyright © 2014 Society for Psychophysiological Research.

  3. Agricultural produce grading and sorting system using color CCD and new color identification algorithm

    NASA Astrophysics Data System (ADS)

    Wang, Dongsheng; Zou, Jizuo; Yang, Yunping; Dong, Jianhua; Zhang, Yuanxiang

    1996-10-01

    A high-speed automatic agricultural produce grading and sorting system using color CCD and new color identification algorithm has been developed. In a typical application, the system can sort almonds into tow output grades according to their color. Almonds ar rich in 18 kinds of amino acids and 13 kinds of micro minerals and vitamins and can be made into almond drink. In order to ensure the drink quality, almonds must be sorted carefully before being made into a drink. Using this system, almonds can be sorted into two grades: up to grade and below grade almonds or foreign materials. A color CCD inspects the almonds passing on a conveyor of rotating rollers, a color identification algorithm grades almonds and distinguishes foreign materials from almonds. Employing an elaborately designed mechanism, the below grade almonds and foreign materials can be removed effectively from the raw almonds. This system can be easily adapted for inspecting and sorting other kinds of agricultural produce such as peanuts, beans tomatoes and so on.

  4. Love waves in functionally graded piezoelectric materials by stiffness matrix method.

    PubMed

    Ben Salah, Issam; Wali, Yassine; Ben Ghozlen, Mohamed Hédi

    2011-04-01

    A numerical matrix method relative to the propagation of ultrasonic guided waves in functionally graded piezoelectric heterostructure is given in order to make a comparative study with the respective performances of analytical methods proposed in literature. The preliminary obtained results show a good agreement, however numerical approach has the advantage of conceptual simplicity and flexibility brought about by the stiffness matrix method. The propagation behaviour of Love waves in a functionally graded piezoelectric material (FGPM) is investigated in this article. It involves a thin FGPM layer bonded perfectly to an elastic substrate. The inhomogeneous FGPM heterostructure has been stratified along the depth direction, hence each state can be considered as homogeneous and the ordinary differential equation method is applied. The obtained solutions are used to study the effect of an exponential gradient applied to physical properties. Such numerical approach allows applying different gradient variation for mechanical and electrical properties. For this case, the obtained results reveal opposite effects. The dispersive curves and phase velocities of the Love wave propagation in the layered piezoelectric film are obtained for electrical open and short cases on the free surface, respectively. The effect of gradient coefficients on coupled electromechanical factor, on the stress fields, the electrical potential and the mechanical displacement are discussed, respectively. Illustration is achieved on the well known heterostructure PZT-5H/SiO(2), the obtained results are especially useful in the design of high-performance acoustic surface devices and accurately prediction of the Love wave propagation behaviour. Copyright © 2010 Elsevier B.V. All rights reserved.

  5. Coronary artery disease concomitant with chronic obstructive pulmonary disease.

    PubMed

    Roversi, Sara; Roversi, Pietro; Spadafora, Giuseppe; Rossi, Rosario; Fabbri, Leonardo M

    2014-01-01

    Numerous epidemiologic studies have linked the presence of chronic obstructive pulmonary disease (COPD) to coronary artery disease (CAD). However, prevalence, pathological processes, clinical manifestations and therapy are still debated, as progress towards uncovering the link between these two disorders has been hindered by the complex nature of multimorbidity. Articles targeting CAD in patients with COPD were identified from the searches of MEDLINE and EMBASE databases in July 2013. Three authors reviewed available evidence, focusing on the latest development on disease prevalence, pathogenesis, clinical manifestations and therapeutic strategies. Both clinical trial and previous reviews have been included in this work. The most accredited hypothesis asserts that the main common risk factors, that is, cigarette smoke and ageing, elicit a chronic low-grade systemic inflammatory response, which affects both cardiovascular endothelial cells and airways/lung parenchyma. The development of CAD in patients with COPD potentiates the morbidity of COPD, leading to increased hospitalizations, mortality and health costs. Moreover, correct diagnosis is challenging and therapies are not clearly defined. Evidence from recently published articles highlights the importance of multimorbidity in patient management and future research. Moreover, many authors emphasize the importance of low-grade systemic inflammation as a common pathological mechanism and a possible future therapeutic target. © 2013 Stichting European Society for Clinical Investigation Journal Foundation. Published by John Wiley & Sons Ltd.

  6. Reclassification of serous ovarian carcinoma by a 2-tier system: a Gynecologic Oncology Group Study.

    PubMed

    Bodurka, Diane C; Deavers, Michael T; Tian, Chunqiao; Sun, Charlotte C; Malpica, Anais; Coleman, Robert L; Lu, Karen H; Sood, Anil K; Birrer, Michael J; Ozols, Robert; Baergen, Rebecca; Emerson, Robert E; Steinhoff, Margaret; Behmaram, Behnaz; Rasty, Golnar; Gershenson, David M

    2012-06-15

    A study was undertaken to use the 2-tier system to reclassify the grade of serous ovarian tumors previously classified using the International Federation of Gynecology and Obstetrics (FIGO) 3-tier system and determine the progression-free survival (PFS) and overall survival (OS) of patients treated on Gynecologic Oncology Group (GOG) Protocol 158. The authors retrospectively reviewed demographic, pathologic, and survival data of 290 patients with stage III serous ovarian carcinoma treated with surgery and chemotherapy on GOG Protocol 158, a cooperative multicenter group trial. A blinded pathology review was performed by a panel of 6 gynecologic pathologists to verify histology and regrade tumors using the 2-tier system. The association of tumor grade with PFS and OS was assessed. Of 241 cases, both systems demonstrated substantial agreement when combining FIGO grades 2 and 3 (overall agreement, 95%; kappa statistic, 0.68). By using the 2-tier system, patients with low-grade versus high-grade tumors had significantly longer PFS (45.0 vs 19.8 months, respectively; P = .01). By using FIGO criteria, median PFS for patients with grade 1, 2, and 3 tumors was 37.5, 19.8, and 20.1 months, respectively (P = .07). There was no difference in clinical outcome in patients with grade 2 or 3 tumors in multivariate analysis. Woman with high-grade versus low-grade tumors demonstrated significantly higher risk of death (hazard ratio, 2.43; 95% confidence interval, 1.17-5.04; P = .02). Women with high-grade versus low-grade serous carcinoma of the ovary are 2 distinct patient populations. Adoption of the 2-tier grading system provides a simple yet precise framework for predicting clinical outcomes. Copyright © 2011 American Cancer Society.

  7. 75 FR 59296 - Agency Information Collection Activities: Submission for the Office of Management and Budget (OMB...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-27

    ..., partnership, commercial grade dedicating entity, or other entity subject to the regulations in this part to... basis for the issuance of numerous NRC Generic Communications that have contributed to the improved...

  8. Nonimaging optical concentrators using graded-index dielectric.

    PubMed

    Zitelli, M

    2014-04-01

    A new generation of inhomogeneous nonimaging optical concentrators is proposed, able to achieve simultaneously high optical efficiency and acceptance solid angle at a given geometrical concentration factor. General design methods are given, and concentrators are numerically investigated and optimized.

  9. [Grading of gynecological tumors : Current aspects].

    PubMed

    Horn, L-C; Mayr, D; Brambs, C E; Einenkel, J; Sändig, I; Schierle, K

    2016-07-01

    Histopathological assessment of the tumor grade and cell type is central to the management and prognosis of various gynecological malignancies. Conventional grading systems for squamous carcinomas and adenocarcinomas of the vulva, vagina and cervix are poorly defined. For endometrioid tumors of the female genital tract as well as for mucinous endometrial, ovarian and seromucinous ovarian carcinomas, the 3‑tiered FIGO grading system is recommended. For uterine neuroendocrine tumors the grading system of the gastrointestinal counterparts has been adopted. Uterine leiomyosarcomas are not graded. Endometrial stromal sarcomas are divided into low and high grades, based on cellular morphology, immunohistochemical and molecular findings. A chemotherapy response score was established for chemotherapeutically treated high-grade serous pelvic cancer. For non-epithelial ovarian malignancies, only Sertoli-Leydig cell tumors and immature teratomas are graded. At this time molecular profiling has no impact on the grading of tumors of the female genital tract.

  10. The Grading System: Does an "A" Really Equal Learning?

    ERIC Educational Resources Information Center

    Haley, Beverly

    1988-01-01

    Good grades on a report card do not necessarily mean the material has been comprehended. This article examines the relative worth of grades; extra credit assignments; categorizing students into A, B, or C boxes; and the role of parental pressures for higher grades. Grading systems should be subordinate to true learning motivation. (MLH)

  11. Job Grading System for Trades and Labor Occupations. Part II.

    ERIC Educational Resources Information Center

    Civil Service Commission, Washington, DC. Bureau of Policies and Standards.

    Three new standards (telephone mechanic, electroplater, and animal caretaker) for grading jobs under the Federal Wage System are cited. There is an alphabetical listing by job for published job grading standards, an occupational code-structure index for published grading standards, and a list of 61 jobs by published job grading standard with…

  12. Analysis of Students’ Incorrect Answers on the Topic of Roman Numerals in The Fourth-Grade of Primary School

    NASA Astrophysics Data System (ADS)

    Selvianiresa, D.; Jupri, Al

    2017-02-01

    Mathematics has an important role in solving problems related to mathematical symbols. Mathematics topics are related to the daily life of students, as well as mathematics in the primary school level. In this paper, we report the results of research that aims to understand the difficulties of primary school students towards mathematics, especially on the topic of Roman numerals. The subject of this research included 38 students of fourth grade students from a primary school in the city of Bandung. The results showed that the teacher is more likely do the learning to deliver topic directly to students, rather than having to relatethe learning with a real context. In addition, after the teacher gave some exercises to students, we observed that there are some students’ answers that are unpredictable and made errors. Unexpected answers are caused by student’s unconscientious, misunderstanding, or inability to memorize in seven Roman numeral in general. The results of this analysis can be used to develop teacher competence in the teaching and learning process in the future. In this way, we expect the teacher can prepare various student responses to the given problems in the learning process.

  13. Characterizing upper urinary tract dilation on ultrasound: a survey of North American pediatric radiologists' practices.

    PubMed

    Swenson, David W; Darge, Kassa; Ziniel, Sonja I; Chow, Jeanne S

    2015-04-01

    Radiologists commonly evaluate children first diagnosed with urinary tract dilation on prenatal ultrasound (US). To establish how North American pediatric radiologists define and report findings of urinary tract dilation on US. A web-based survey was sent to North American members of the Society for Pediatric Radiology (SPR) from January to February 2014. Reporting practices and interpretation of three image-based cases using free text were queried. Responses to close-ended questions were analyzed with descriptive statistics, while free-text responses to the three cases were categorized and analyzed as (1) using either descriptive terminology or an established numerical grading system and (2) as providing a quantitative term for the degree of dilation. Two hundred eighty-four pediatric radiologists answered the survey resulting in a response rate of 19.0%. There is a great variety in the terms used to describe urinary tract dilation with 66.2% using descriptive terminology, 35.6% using Society for Fetal Urology (SFU) grading system and 35.9% measuring anterior-posterior diameter (APD) of the renal pelvis. There is no consensus for a normal postnatal APD or the meaning of hydronephrosis. For the same images, descriptions vary widely in degree of severity ranging from normal to mild to severe. Similar variability exists among those using the SFU system. Ninety-seven percent say they believe a unified descriptive system would be helpful and 87.7% would use it if available. Pediatric radiologists do not have a standardized method for describing urinary tract dilation but have a great desire for such a system and would follow it if available.

  14. Utilizing constructivism learning theory in collaborative testing as a creative strategy to promote essential nursing skills.

    PubMed

    Duane, Barbara T; Satre, Maria E

    2014-01-01

    In nursing education, students participate in individual learner testing. This process follows the instructionist learning theory of a system model. However, in the practice of nursing, success depends upon collaboration with numerous people in different capacities, critical thinking, clinical reasoning, and the ability to communicate with others. Research has shown that collaborative testing, a constructivism learning activity and a form of collaborative learning, enhances students' abilities to master these areas. Collaborative testing is a clear, creative strategy which constructivists would say supports the socio-linguistic base of their learning theory. The test becomes an active implementation of peer-mediated learning where individual knowledge is enhanced through problem solving or defense of an individual position with the collaborative method. There is criticism for the testing method's potential of grade inflation and for students to receive grade benefits with little effort. After a review of various collaborative testing methods, this nursing faculty implemented a collaborative testing format that addresses both the positive and negative aspects of the process. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Hygrothermal Material Properties for Soils in Building Science

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kehrer, Manfred; Pallin, Simon B.

    2017-01-01

    Hygrothermal performance of soils coupled to buildings is complicated because of the dearth of information on soil properties. However they are important when numerical simulation of coupled heat and moisture transport for below-grade building components are performed as their temperature and moisture content has an influence on the durability of the below-grade building component. Soils can be classified by soil texture. According to the Unified Soil Classification System (USCA), 12 different soils can be defined on the basis of three soil components: clay, sand, and silt. This study shows how existing material properties for typical American soils can be transferredmore » and used for the calculation of the coupled heat and moisture transport of building components in contact with soil. Furthermore a thermal validation with field measurements under known boundary conditions is part of this study, too. Field measurements for soil temperature and moisture content for two specified soils are carried out right now under known boundary conditions. As these field measurements are not finished yet, the full hygrothermal validation is still missing« less

  16. Preliminary work in developing sawbolt grading systems for white oak

    Treesearch

    Everette D. Rast; Everette D. Rast

    1971-01-01

    This paper is principally a description of one technique used in the development of white oak (Quercus alba L.) sawbolt grades--not a final sawbolt grading system for the species over its range. This technique can be used by anyone in developing other bolt-grade specifications or in refining the system presented in this paper.

  17. Specifications-Based Grading in an Introduction to Proofs Course

    ERIC Educational Resources Information Center

    Williams, Kristopher

    2018-01-01

    This article describes a system of specifications-based grading used in an introduction to proofs course. The system was introduced to address two issues that arose in the course: how to spend less time grading and how to encourage use of feedback. We describe the implementation of the system and the results on grading and on students.

  18. Study of the seismic performance of hybrid A-frame micropile/MSE (mechanically stabilized earth) wall

    NASA Astrophysics Data System (ADS)

    Chen, Yumin; Zhang, Zhichao; Liu, Hanlong

    2017-04-01

    The Hybrid A-Frame Micropile/MSE (mechanically stabilized earth) Wall suitable for mountain roadways is put forward in this study: a pair of vertical and inclined micropiles goes through the backfill region of a highway MSE Wall from the road surface and are then anchored into the foundation. The pile cap and grade beam are placed on the pile tops, and then a road barrier is connected to the grade beam by connecting pieces. The MSE wall's global stability, local stability and impact resistance of the road barrier can be enhanced simultaneously by this design. In order to validate the serviceability of the hybrid A-frame micropile/MSE wall and the reliability of the numerical method, scale model tests and a corresponding numerical simulation were conducted. Then, the seismic performance of the MSE walls before and after reinforcement with micropiles was studied comparatively through numerical methods. The results indicate that the hybrid A-frame micropile/MSE wall can effectively control earthquake-induced deformation, differential settlement at the road surface, bearing pressure on the bottom and acceleration by means of a rigid-soft combination of micropiles and MSE. The accumulated displacement under earthquakes with amplitude of 0.1‒0.5 g is reduced by 36.3%‒46.5%, and the acceleration amplification factor on the top of the wall is reduced by 13.4%, 15.7% and 19.3% based on 0.1, 0.3 and 0.5 g input earthquake loading, respectively. In addition, the earthquake-induced failure mode of the MSE wall in steep terrain is the sliding of the MSE region along the backslope, while the micropiles effectively control the sliding trend. The maximum earthquake-induced pile bending moment is in the interface between MSE and slope foundation, so it is necessary to strengthen the reinforcement of the pile body in the interface. Hence, it is proven that the hybrid A-frame micropile/MSE wall system has good seismic performance.

  19. Himalayan tectonics explained by extrusion of a low-viscosity crustal channel coupled to focused surface denudation.

    PubMed

    Beaumont, C; Jamieson, R A; Nguyen, M H; Lee, B

    2001-12-13

    Recent interpretations of Himalayan-Tibetan tectonics have proposed that channel flow in the middle to lower crust can explain outward growth of the Tibetan plateau, and that ductile extrusion of high-grade metamorphic rocks between coeval normal- and thrust-sense shear zones can explain exhumation of the Greater Himalayan sequence. Here we use coupled thermal-mechanical numerical models to show that these two processes-channel flow and ductile extrusion-may be dynamically linked through the effects of surface denudation focused at the edge of a plateau that is underlain by low-viscosity material. Our models provide an internally self-consistent explanation for many observed features of the Himalayan-Tibetan system.

  20. Early Predictors of Middle School Fraction Knowledge

    PubMed Central

    Bailey, Drew H.; Siegler, Robert S.; Geary, David C.

    2014-01-01

    Recent findings that earlier fraction knowledge predicts later mathematics achievement raise the question of what predicts later fraction knowledge. Analyses of longitudinal data indicated that whole number magnitude knowledge in first grade predicted knowledge of fraction magnitudes in middle school, controlling for whole number arithmetic proficiency, domain general cognitive abilities, parental income and education, race, and gender. Similarly, knowledge of whole number arithmetic in first grade predicted knowledge of fraction arithmetic in middle school, controlling for whole number magnitude knowledge in first grade and the other control variables. In contrast, neither type of early whole number knowledge uniquely predicted middle school reading achievement. We discuss the implications of these findings for theories of numerical development and for improving mathematics learning. PMID:24576209

  1. Dynamics and optimal control of a non-linear epidemic model with relapse and cure

    NASA Astrophysics Data System (ADS)

    Lahrouz, A.; El Mahjour, H.; Settati, A.; Bernoussi, A.

    2018-04-01

    In this work, we introduce the basic reproduction number R0 for a general epidemic model with graded cure, relapse and nonlinear incidence rate in a non-constant population size. We established that the disease free-equilibrium state Ef is globally asymptotically exponentially stable if R0 < 1 and globally asymptotically stable if R0 = 1. If R0 > 1, we proved that the system model has at least one endemic state Ee. Then, by means of an appropriate Lyapunov function, we showed that Ee is unique and globally asymptotically stable under some acceptable biological conditions. On the other hand, we use two types of control to reduce the number of infectious individuals. The optimality system is formulated and solved numerically using a Gauss-Seidel-like implicit finite-difference method.

  2. Ultrasensitivity by Molecular Titration in Spatially Propagating Enzymatic Reactions

    PubMed Central

    Semenov, Sergey N.; Markvoort, Albert J.; Gevers, Wouter B.L.; Piruska, Aigars; de Greef, Tom F.A.; Huck, Wilhelm T.S.

    2013-01-01

    Delineating design principles of biological systems by reconstitution of purified components offers a platform to gauge the influence of critical physicochemical parameters on minimal biological systems of reduced complexity. Here we unravel the effect of strong reversible inhibitors on the spatiotemporal propagation of enzymatic reactions in a confined environment in vitro. We use micropatterned, enzyme-laden agarose gels which are stamped on polyacrylamide films containing immobilized substrates and reversible inhibitors. Quantitative fluorescence imaging combined with detailed numerical simulations of the reaction-diffusion process reveal that a shallow gradient of enzyme is converted into a steep product gradient by addition of strong inhibitors, consistent with a mathematical model of molecular titration. The results confirm that ultrasensitive and threshold effects at the molecular level can convert a graded input signal to a steep spatial response at macroscopic length scales. PMID:23972857

  3. Basic numerical capacities and prevalence of developmental dyscalculia: the Havana Survey.

    PubMed

    Reigosa-Crespo, Vivian; Valdés-Sosa, Mitchell; Butterworth, Brian; Estévez, Nancy; Rodríguez, Marisol; Santos, Elsa; Torres, Paul; Suárez, Ramón; Lage, Agustín

    2012-01-01

    The association of enumeration and number comparison capacities with arithmetical competence was examined in a large sample of children from 2nd to 9th grades. It was found that efficiency on numerical capacities predicted separately more than 25% of the variance in the individual differences on a timed arithmetical test, and this occurred for both younger and older learners. These capacities were also significant predictors of individual variations in an untimed curriculum-based math achievement test and on the teacher scores of math performance over developmental time. Based on these findings, these numerical capacities were used for estimating the prevalence and gender ratio of basic numerical deficits and developmental dyscalculia (DD) over the grade range defined above (N = 11,652 children). The extent to which DD affects the population with poor ability on calculation was also examined. For this purpose, the prevalence and gender ratio of arithmetical dysfluency (AD) were estimated in the same cohort. The estimated prevalence of DD was 3.4%, and the male:female ratio was 4:1. However, the prevalence of AD was almost 3 times as high (9.35%), and no gender differences were found (male:female ratio = 1.07:1). Basic numerical deficits affect 4.54% of school-age population and affect more boys than girls (2.4:1). The differences between the corresponding estimates were highly significant (α < .01). Based on these contrastive findings, it is concluded that DD, defined as a defective sense of numerosity, could be a distinctive disorder that affects only a portion of children with AD.

  4. Prostate cancer: from Gleason scoring to prognostic grade grouping.

    PubMed

    Montironi, Rodolfo; Santoni, Matteo; Mazzucchelli, Roberta; Burattini, Luciano; Berardi, Rossana; Galosi, Andrea B; Cheng, Liang; Lopez-Beltran, Antonio; Briganti, Alberto; Montorsi, Francesco; Scarpelli, Marina

    2016-01-01

    The Gleason grading system was developed in the late 1960s by Dr. Donald F. Gleason. Due to changes in prostatic adenocarcinoma (PAC) detection and treatment, newer technologies to better characterize prostatic pathology, subsequently described variants of PAC and further data relating various morphologic patterns to prognosis, the application of the Gleason grading system changed substantially in surgical pathology. First in 2005 and more recently in 2014, consensus conferences were held to update PAC grading. Here, we review of the successive changes in the grading of PAC from the original system, with emphasis on the newest prognostic grade grouping.

  5. Selective Laser Treatment on Cold-Sprayed Titanium Coatings: Numerical Modeling and Experimental Analysis

    NASA Astrophysics Data System (ADS)

    Carlone, Pierpaolo; Astarita, Antonello; Rubino, Felice; Pasquino, Nicola; Aprea, Paolo

    2016-12-01

    In this paper, a selective laser post-deposition on pure grade II titanium coatings, cold-sprayed on AA2024-T3 sheets, was experimentally and numerically investigated. Morphological features, microstructure, and chemical composition of the treated zone were assessed by means of optical microscopy, scanning electron microscopy, and energy dispersive X-ray spectrometry. Microhardness measurements were also carried out to evaluate the mechanical properties of the coating. A numerical model of the laser treatment was implemented and solved to simulate the process and discuss the experimental outcomes. Obtained results highlighted the key role played by heat input and dimensional features on the effectiveness of the treatment.

  6. Exploring Academic Performance: Looking beyond Numerical Grades

    ERIC Educational Resources Information Center

    Martin Sanz, Noemy; Rodrigo, Inés G.; Izquierdo García, Cristina; Ajenjo Pastrana, Patricia

    2017-01-01

    Academic performance has always been associated to the evaluation tests results, which are those corresponding to student's IQ, and leaving aside other personal characteristics. Among such characteristics, the importance of emotional intelligence is worth highlighting (management, facilitation, understanding and perception), dimensions associated…

  7. Dog Mathematics: Exploring Base-4

    ERIC Educational Resources Information Center

    Kurz, Terri L.; Yanik, H. Bahadir; Lee, Mi Yeon

    2016-01-01

    Using a dog's paw as a basis for numerical representation, sixth grade students explored how to count and regroup using the dog's four digital pads. Teachers can connect these base-4 explorations to the conceptual meaning of place value and regrouping using base-10.

  8. Linear spectral response of a Fano-resonant graded-stub filter based on pillar-photonic-crystal waveguides.

    PubMed

    Tokushima, Masatoshi

    2018-02-01

    To achieve high spectral linearity, we developed a Fano-resonant graded-stub filter on the basis of a pillar-photonic-crystal (PhC) waveguide. In a numerical simulation, the availability of a linear region within a peak-to-bottom wavelength span was nearly doubled compared to that of a sinusoidal spectrum, which was experimentally demonstrated with a fabricated silicon-pillar PhC stub filter. The high linearity of this filter is suitable for optical modulators used in multilevel amplitude modulation.

  9. A fuzzy inventory model with acceptable shortage using graded mean integration value method

    NASA Astrophysics Data System (ADS)

    Saranya, R.; Varadarajan, R.

    2018-04-01

    In many inventory models uncertainty is due to fuzziness and fuzziness is the closed possible approach to reality. In this paper, we proposed a fuzzy inventory model with acceptable shortage which is completely backlogged. We fuzzily the carrying cost, backorder cost and ordering cost using Triangular and Trapezoidal fuzzy numbers to obtain the fuzzy total cost. The purpose of our study is to defuzzify the total profit function by Graded Mean Integration Value Method. Further a numerical example is also given to demonstrate the developed crisp and fuzzy models.

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cheng, Liwen, E-mail: lwcheng@yzu.edu.cn; Wu, Shudong; Xia, Changquan

    In this work, graded barrier InGaN light-emitting diodes with increasing indium composition barriers are proposed and investigated numerically. When the conventional GaN barriers are replaced by this unique graded InGaN barrier design, the forward voltage at 100 mA is reduced from 3.32 V to 3.27 V, and the efficiency droop is improved from 46.6% to 7.5%. The simulation results observed in this work indicate that these improvements can be attributed to increased electron confinement and enhanced hole injection efficiency caused by the modified energy band diagram.

  11. User's guide to UGRS: the Ultimate Grading and Remanufacturing System (version 5.0).

    Treesearch

    John Moody; Charles J. Gatchell; Elizabeth S. Walker; Powsiri Klinkhachorn

    1998-01-01

    The Ultimate Grading and Remanufacturing System (UGRS) is the latest generation of advanced computer programs for lumber grading. It is designed to be a training and research tool that allows grading of lumber according to 1998 NHLA rules and remanufacturing for maximum dollar value. A 32-bit application that runs under all Microsoft Windows operating systems, UGRS...

  12. Intentional and automatic numerical processing as predictors of mathematical abilities in primary school children

    PubMed Central

    Pina, Violeta; Castillo, Alejandro; Cohen Kadosh, Roi; Fuentes, Luis J.

    2015-01-01

    Previous studies have suggested that numerical processing relates to mathematical performance, but it seems that such relationship is more evident for intentional than for automatic numerical processing. In the present study we assessed the relationship between the two types of numerical processing and specific mathematical abilities in a sample of 109 children in grades 1–6. Participants were tested in an ample range of mathematical tests and also performed both a numerical and a size comparison task. The results showed that numerical processing related to mathematical performance only when inhibitory control was involved in the comparison tasks. Concretely, we found that intentional numerical processing, as indexed by the numerical distance effect in the numerical comparison task, was related to mathematical reasoning skills only when the task-irrelevant dimension (the physical size) was incongruent; whereas automatic numerical processing, indexed by the congruency effect in the size comparison task, was related to mathematical calculation skills only when digits were separated by small distance. The observed double dissociation highlights the relevance of both intentional and automatic numerical processing in mathematical skills, but when inhibitory control is also involved. PMID:25873909

  13. Design and characterization of dielectric subwavelength focusing lens with polarization dependence

    NASA Astrophysics Data System (ADS)

    Kim, Sung W.; Pang, Lin; Fainman, Yeshaiahu

    2016-03-01

    We introduce and develop design, fabrication and characterization methodology for engineering the effective refractive index of a composite dielectric planar surface created by controlling the density of deeply subwavelength low index nanoholes (e.g., air) in a high index dielectric layer (e.g., Si). The nanoscale properties of a composite dielectric layer allows for full control of the optical wavefront phase by designing arbitrary space-variant refractive index profiles. We present the composite dielectric metasurface microlens exploiting symmetric design to achieve polarization invariant impulse response, and use asymmetric design to demonstrate polarization sensitive impulse response of the lens. This composite dielectric layers lenses were fabricated by patterning nanohole distributions on a dielectric surface and etching to submicron depths. Our dielectric microlens with asymmetric distribution of neff (neff x ≠ neff y) demonstrates a graded index lens with polarization dependent focusing with of 32um and 22 um for linearly x- and y-polarized light, respectively operating at a wavelength of λ = 1550nm. We also show numerically and demonstrate experimentally achromatic performance of the devices operating in the wavelength range of 1500nm - 1900nm with FWHM of the focal spots of about 4um. Namely, we have constructed a graded index lens that can overcome diffraction effects even when aperture/wavelength (D/λ) is smaller than 40. The demonstrated novel approach to engineer dielectric composite nanosurfaces has the potential to realize arbitrary phase functions with minimal insertion loss, submicron thickness and miniaturization to reduce element size and weight, and may have a significant impact on numerous miniature imaging systems applications.

  14. Report on METHODS OF Evaluating Students at the University of California, Berkeley.

    ERIC Educational Resources Information Center

    Miller, Stuart

    Several arguments are made for changing the present system of grading in college. The arguments deal with: (1) the negative effect of grading on the teaching situation--the system is capricious and variable and encourages "grade grubbing"; (2) the lack of accuracy and uniformity of grades; (3) the effect of grading, as an enforcer of the…

  15. Development of Product Relatedness and Distance Effects in Typical Achievers and in Children With Mathematics Learning Disabilities.

    PubMed

    Rotem, Avital; Henik, Avishai

    2015-01-01

    The current study examined the development of two effects that have been found in single-digit multiplication errors: relatedness and distance. Typically achieving (TA) second, fourth, and sixth graders and adults, and sixth and eighth graders with a mathematics learning disability (MLD) performed a verification task. Relatedness was defined by a slow and inaccurate response to false results that were related to one of the operands via a shared multiplication row (e.g., 3 × 4 = 16). Distance was defined by a slow and inaccurate response to false results that were close in magnitude to the true result (e.g., 6 × 8 = 49). The presence of these effects indicates that participants are sensitive to numerical features of products. TA children demonstrated sensitivity to relatedness and distance from second grade onward. With age their sensitivity expanded from easy problems (e.g., 2 × 3) to difficult ones (e.g., 8 × 9). Children with MLD were sensitive to relatedness on easy problems. Their sensitivity to distance differed from the pattern seen in sixth grade and was partial in eighth grade. The presence of numerical sensitivity in children with MLD calls for instructional methods that would further develop their number sense. © Hammill Institute on Disabilities 2014.

  16. Categorization of intraoperative ureteroscopy complications using modified Satava classification system.

    PubMed

    Tepeler, Abdulkadir; Resorlu, Berkan; Sahin, Tolga; Sarikaya, Selcuk; Bayindir, Mirze; Oguz, Ural; Armagan, Abdullah; Unsal, Ali

    2014-02-01

    To review our experience with ureteroscopy (URS) in the treatment of ureteral calculi and stratify intraoperative complications of URS according to the modified Satava classification system. We performed a retrospective analysis of 1,208 patients (672 males and 536 females), with a mean age of 43.1 years (range 1-78), who underwent ureteroscopic procedures for removal of ureteral stones. Intraoperative complications were recorded according to modified Satava classification system. Grade 1 complications included incidents without consequences for the patient; grade 2 complications, which are treated intraoperatively with endoscopic surgery (grade 2a) or required endoscopic re-treatment (grade 2b); and grade 3 complications included incidents requiring open or laparoscopic surgery. The stones were completely removed in 1,067 (88.3%) patients after primary procedure by either simple extraction or after fragmentation. The overall incidence of intraoperative complications was 12.6%. The most common complications were proximal stone migration (3.9%), mucosal injury (2.8%), bleeding (1.9%), inability to reach stone (1.8%), malfunctioning or breakage of instruments (0.8%), ureteral perforation (0.8%) and ureteral avulsion (0.16%). According to modified Satava classification system, there were 4.5% grade 1; 4.4% grade 2a; 3.2% grade 2b; and 0.57% grade 3 complications. We think that modified Satava classification is a quick and simple system for describing the severity of intraoperative URS complications and this grading system will facilitate a better comparison for the surgical outcomes obtained from different centers.

  17. Teaching of the Society for Fetal Urology grading system for pediatric hydronephrosis is improved by e-Learning using Computer Enhanced Visual Learning (CEVL): A multi-institutional trial.

    PubMed

    Liu, Dennis B; Palmer, Blake; Herndon, C D Anthony; Maizels, Max

    2015-08-01

    It is unclear how clinicians learn to grade pediatric hydronephrosis (HN) and how effective their training has been. We sought to: 1. Assess how clinicians learn to grade HN and their confidence in their training and abilities and 2. To assess Computer Enhanced Visual Learning (CEVL) e-Learning to learn the Society for Fetal Urology (SFU) grading system for pediatric HN. A multi-institutional online survey was distributed to pediatric urologists, nephrologists, and radiologists. Respondents used a 6-point Likert scale (0 = not confident to 5 = very confident) to assess their confidence in knowledge of the criteria, indications, and ability to grade HN, and how they learned to grade. Participants assigned SFU grades to 15 neonatal ultrasounds (US). A CEVL module on the SFU grading system was accessed and a post-CEVL survey completed. Changes in confidence and accuracy of grading were compared before and after CEVL e-Learning. The most common method of learning was "casually during training" (44.5%). Significant increases in confidence in knowledge of criteria, indications, and ability to grade, as well as the accuracy of grading were seen following CEVL e-Learning (Figure A and B). Although the SFU grading system is considered the predominant grading system for HN, its application in clinical practice has been inconsistent. While this may be due to the grading system itself, it is possible that deficient training and confidence are the root causes. Our data supports this by demonstrating that most clinicians receive only casual training and accordingly, report low confidence in their knowledge and ability to grade HN. Therefore, we conclude that there exists a strong need to improve the teaching of the SFU grading system. e-Learning has been shown to be effective in teaching difficult topics and skills. We demonstrate that e-Learning with CEVL is effective in increasing both the confidence and accuracy of SFU grading of pediatric HN. Limitations of our study include a small sample size, low response rate, and discrepant participation. Furthermore, we did not assess the extent to which the CEVL module was used or include a control group learning through traditional means. Therefore, we were unable to evaluate the efficiency of learning or be certain that the improvements seen were derived exclusively from CEVL. Current training in SFU grading of HN is mostly unstructured and inaccurate grading is common. Learners who use CEVL show improvements in their confidence and ability to SFU grade HN. Copyright © 2015 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.

  18. High apoptotic index in urine cytology is associated with high-grade urothelial carcinoma.

    PubMed

    Yang, Chi-Shun; Chen, Shaoxiong; Cramer, Harvey M; Wu, Howard H

    2016-08-01

    The significance of apoptosis and its association with high-grade urothelial carcinoma (HGUC) in urine cytology has yet to be determined. A computerized search of the study laboratory information system was performed over a 3-year period for all urine cytology specimens processed using the SurePath liquid-based preparation technique. Only those cases with correlating surgical pathology obtained within 6 months after the urine cytologic samples were included in the current study. Cases from ileal conduit samples were excluded. A semiquantitative numerical scoring system (apoptotic index) was used to assess the amount of pyknosis or karyorrhexis, with 0 indicating none, 1 indicating < 10 per 10 high-power fields, 2 indicating 10 to 30 per 10 high-power fields, and 3 indicating > 30 per 10 high-power fields. Statistical analysis using the Pearson chi-square test was performed. A total of 228 cases including 105 benign cases, 79 cases of HGUC, and 44 cases of low-grade urothelial carcinoma (LGUC) diagnosed on follow-up surgical pathology were selected. A score of 0 was observed in 70 benign, 11 HGUC, and 8 LGUC cases; a score of 1 was observed in 31 benign, 21 HGUC, and 23 LGUC cases; a score of 2 was observed in 3 benign, 27 HGUC, and 9 LGUC cases; and a score of 3 was observed in 1 benign, 20 HGUC, and 4 LGUC cases. Excluding ileal conduit urine specimens, the finding of a high apoptotic index (score ≥ 2) with the presence of pyknosis or karyorrhexis in ≥10 per 10 high-power fields in the urine cytology appears to be significantly associated with HGUC (P<.05). Cancer Cytopathol 2016;124:546-51. © 2016 American Cancer Society. © 2016 American Cancer Society.

  19. Pediatric airway study: Endoscopic grading system for quantifying tonsillar size in comparison to standard adenotonsillar grading systems.

    PubMed

    Patel, Neha A; Carlin, Kristen; Bernstein, Joseph M

    Current grading systems may not allow clinicians to reliably document and communicate adenotonsillar size in the clinical setting. A validated endoscopic grading system may be useful for reporting tonsillar size in future clinical outcome studies. This is especially important as tonsillar enlargement is the cause of a substantial health care burden on children. To propose and validate an easy-to-use flexible fiberoptic endoscopic grading system that provides physicians with a more accurate sense of the three-dimensional relationship of the tonsillar fossa to the upper-airway. 50 consecutive pediatric patients were prospectively recruited between February 2015 and February 2016 at a pediatric otolaryngology outpatient clinic. The patients had no major craniofacial abnormalities and were aged 1 to 16years. Each patient had data regarding BMI, Friedman palate position, OSA-18 survey results collected. For each child, digital video clips of fiberoptic nasopharyngeal, oropharyngeal and laryngeal exams were presented to 2 examiners. Examiners were asked to independently use the proposed Endoscopic tonsillar grading system, the Brodsky tonsillar grading scale, the Modified Brodsky tonsillar grading scale with a tongue depressor, and the Parikh adenoid grading system to rate adenotonsillar hypertrophy. Cohen's Kappa and weighted Kappa scores were used to assess interrater reliability for each of the four grading scales. The Spearman correlation was used to test the associations between each scale and OSA-18 scores, as well as Body Mass Index (BMI). 50 pediatric patients were included in this study (mean age 6.1years, range of 1year to 16years). The average BMI was 20. The average OSA-18 score was 61.7. The average Friedman palate position score was 1.34. Twelve percent of the patients had a Friedman palate position score≥3, which made traditional Brodsky grading of their tonsils impossible without a tongue depressor. All four scales showed strong agreement between the two raters. The weighted Kappa was 0.83 for the Modified Brodsky scale, 0.89 for the Brodsky scale, 0.94 for the Parikh scale to 0.98 for the Endoscopic scale (almost perfect agreement). The Endoscopic scale showed the most consistent agreement between the raters during the study. There was a moderate association between the Parikh adenoid grading system with OSA-18 scores (Spearman's ρ=0.58, p<0.001) compared to a low association of the tonsillar grading systems with OSA- 18 scores. None of the scales correlated with patient BMI. The proposed Endoscopic tonsillar grading system is as reliable of a method of grading tonsillar size as conventional grading systems. It offers the advantage of allowing for critical evaluation of the tonsils without any anatomic distortion which may occur with the use of a tongue blade. This new validated endoscopic grading system provides a tool for communicating the degree of airway obstruction at the level of the oropharynx regardless of Friedman palate position and may be used in future outcomes projects. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. MORPHOLOGICAL PATTERN AND FREQUENCY OF CENTRAL NERVOUS SYSTEM TUMOURS IN CHILDREN.

    PubMed

    Bilqees, Fatima; Samina, Khaleeq; Mohammad, Tahir; Khaleeq-uz-Zamaan

    2016-01-01

    Recent studies, including a comprehensive study by National Cancer Institute, have shown that a significant increase in the incidence of childhood brain tumours makes them the most common paediatric tumour. The objectives of this study were to determine the frequency of central nervous system tumours in paediatric age group (0-12 years), and to segregate various morphologic types according to WHO classification. The study included consecutive cases of central nervous system tumours diagnosed in children in the histopathology department at Federal Government Polyclinic, PGMI, Islamabad, during a period of 4.8 years (Jan 2009-Aug 2013). The initial histopathological evaluation of these lesions was performed on H&E stained sections of paraffin embedded tissues. Special stains and immunohistochemistry were performed whenever indicated. Out of 75 cases, 34 (45.3%) were astrocytic tumours, including 16 (47.1%) Pilocytic astrocytomas (WHO Grade-I), 1 (2.9%) diffuse fibrillary astrocytoma (WHO Grade-II), 1 (2.9%) anaplastic astrocytoma (WHO Grade-III) and 16(47.1%) glioblastoma multiforme (WHO Grade-IV); 18 (24%) were embryonal tumours including 17 (94.4%) medulloblastoma (WHO Grade-IV) and 1 (5.6%) neuroblastoma (WHO Grade IV); 10 (13.3%) were craniopharyngiomas (WHO Grade-I) and 5 (6.7%) were ependymal tumours including 1 (20%) myxopapillary ependymoma (WHO Grade-I) and 4 (80%) ependymomas (WHO Grade-II). Miscellaneous entities included 3 (4%) choroid plexus tumours; 1 (2%) anaplastic oligodendroglioma (WHO Grade-III); 1 (2%) atypical meningioma (WHO Grade-II); 1 (2%) schwannoma (WHO Grade-I); 1 (2%) neurofibroma (WHO Grade-I) and 1 (2%) lipoma (WHO Grade-I). Astrocytic tumours are the most common central nervous system tumours in paediatric age group and high grade lesions (WHO Grade-IV) constitute the largest category (45.3%).

  1. Validity of multiple stress creep recovery (MSCR) test for DOTD asphalt binder specification : final report 564.

    DOT National Transportation Integrated Search

    2017-09-01

    Numerous studies have shown that G*/Sin, the high temperature specification parameter for current Performance Graded (PG) asphalt binder is not adequate to reflect the rutting characteristics of polymer-modified binders. Consequently, many state De...

  2. Extending Poetry.

    ERIC Educational Resources Information Center

    Brodie, Carolyn S.

    1995-01-01

    Discussion of the use of poetry in the classroom highlights 15 poetry books and suggests numerous activities appropriate for grades 2 through 5 in the subject areas of African Americans, birds, color, discoveries, families, food/eating, haiku, multiculturalism, Native Americans, nature, New England, Paul Revere/biographies, seasons, trains, and…

  3. Listening Skills Handbook.

    ERIC Educational Resources Information Center

    Decatur Public Schools District 61, IL.

    Defining listening as the active and conscious process of hearing, recognizing, and interpreting or comprehending language, this guide provides numerous activities to promote the listening skills of primary and intermediate grade students. Specifically, the activities described seek to develop (1) the ability of young students to listen…

  4. Effect of installation location on railroad horn sound levels.

    DOT National Transportation Integrated Search

    2002-06-17

    (FRA) issuance of a Proposed Rule for the Use of Locomotive Horns at Highway-Rail : Grade Crossings1. This rule contains numerous provisions, two of which are addressed : in this study. The first provision addressed in this study states that th...

  5. Automated egg grading system using computer vision: Investigation on weight measure versus shape parameters

    NASA Astrophysics Data System (ADS)

    Nasir, Ahmad Fakhri Ab; Suhaila Sabarudin, Siti; Majeed, Anwar P. P. Abdul; Ghani, Ahmad Shahrizan Abdul

    2018-04-01

    Chicken egg is a source of food of high demand by humans. Human operators cannot work perfectly and continuously when conducting egg grading. Instead of an egg grading system using weight measure, an automatic system for egg grading using computer vision (using egg shape parameter) can be used to improve the productivity of egg grading. However, early hypothesis has indicated that more number of egg classes will change when using egg shape parameter compared with using weight measure. This paper presents the comparison of egg classification by the two above-mentioned methods. Firstly, 120 images of chicken eggs of various grades (A–D) produced in Malaysia are captured. Then, the egg images are processed using image pre-processing techniques, such as image cropping, smoothing and segmentation. Thereafter, eight egg shape features, including area, major axis length, minor axis length, volume, diameter and perimeter, are extracted. Lastly, feature selection (information gain ratio) and feature extraction (principal component analysis) are performed using k-nearest neighbour classifier in the classification process. Two methods, namely, supervised learning (using weight measure as graded by egg supplier) and unsupervised learning (using egg shape parameters as graded by ourselves), are conducted to execute the experiment. Clustering results reveal many changes in egg classes after performing shape-based grading. On average, the best recognition results using shape-based grading label is 94.16% while using weight-based label is 44.17%. As conclusion, automated egg grading system using computer vision is better by implementing shape-based features since it uses image meanwhile the weight parameter is more suitable by using weight grading system.

  6. Independent contributions of the central executive, intelligence, and in-class attentive behavior to developmental change in the strategies used to solve addition problems.

    PubMed

    Geary, David C; Hoard, Mary K; Nugent, Lara

    2012-09-01

    Children's (N=275) use of retrieval, decomposition (e.g., 7=4+3 and thus 6+7=6+4+3), and counting to solve additional problems was longitudinally assessed from first grade to fourth grade, and intelligence, working memory, and in-class attentive behavior was assessed in one or several grades. The goal was to assess the relation between capacity of the central executive component of working memory, controlling for intelligence and in-class attentive behavior, and grade-related changes in children's use of these strategies. The predictor on intercept effects from multilevel models revealed that children with higher central executive capacity correctly retrieved more facts and used the most sophisticated counting procedure more frequently and accurately than their lower capacity peers at the beginning of first grade, but the predictor on slope effects indicated that this advantage disappeared (retrieval) or declined in importance (counting) from first grade to fourth grade. The predictor on slope effects also revealed that from first grade to fourth grade, children with higher capacity adopted the decomposition strategy more quickly than other children. The results remained robust with controls for children's sex, race, school site, speed of encoding Arabic numerals and articulating number words, and mathematics achievement in kindergarten. The results also revealed that intelligence and in-class attentive behavior independently contributed to children's strategy development. Copyright © 2012 Elsevier Inc. All rights reserved.

  7. [Neuroendocrine neoplasm of digestive system with different grades: a clinicopathologic and prognostic study].

    PubMed

    Zhang, Ming-hui; Liu, Yan-hui; Luo, Xin-lan; Lin, Xing-tao; Zhuang, Heng-guo

    2012-07-01

    To study the clinicopathologic and prognostic features of neuroendocrine neoplasm of digestive system with different grades. The clinicopathologic features of 139 cases of neuroendocrine neoplasm occurring in digestive system were retrospectively reviewed and graded according to the 2010 World Health Organization classification of tumours of the digestive system. Immunohistochemical study for synaptophysin, chromogranin A and Ki-67 was carried out. The follow-up and survival data were analysed using Kaplan-Meier method. Prognostic factors were tested by Log-rank testing and independent risk factors were analysed using Cox regression model. Amongst the 139 cases studied, there were 88 cases (63.3%) of grade 1 tumors, 9 cases (6.5%) of grade 2 tumors and 42 cases (30.2%) of grade 3 tumors. There was diffusely positive staining for synaptophysin and chromogranin A in most of the grade 1 and grade 2 tumors. The staining in grade 3 tumors however was focal (P < 0.05). The differences in tumor size, depth of invasion, presence of tumor emboli, perineural permeation, nodal involvement, distant metastasis and survival rate amongst the three groups was statistically significant (P < 0.05). There is significant difference in the clinicopathologic and prognostic features of neuroendocrine neoplasm of digestive system with different grades. It is considered as an independent prognostic factor and represents a useful tool for prognostic evaluation of such tumors, both in clinical practice and research.

  8. Diagnostic accuracy of pre-treatment biopsy for grading cutaneous mast cell tumours in dogs.

    PubMed

    Shaw, T; Kudnig, S T; Firestone, S M

    2018-06-01

    Mast cell tumours (MCTs) are common tumours of the canine skin, and are estimated to represent up to 20% of all skin tumours in dogs. Tumour grade has a major impact on the incidence of local recurrence and metastatic potential. In addition to helping the clinician with surgical planning, knowledge of the tumour grade also assists in proper prognostication and client education. For pre-treatment biopsies to be useful, there must exist a high level of correlation between the histopathological grade obtained from the pre-treatment biopsy and the actual histopathological grade from the excisional biopsy. The aim of this study was to determine concordance of tumour grade between various biopsy techniques (wedge, punch, needle core) and the "gold standard" excisional biopsy method. We found an overall concordance rate of 96% based on the Patnaik grading system, and an overall concordance rate of 92% based on the Kiupel grading system. The accuracy of the various biopsy techniques (wedge, punch and needle core) when compared with excisional biopsy was 92%, 100% and 100%, respectively, based on the Patnaik grading system, and 90%, 95% and 100%, respectively, based on the Kiupel grading system. Of the cases with discordant results, the pre-treatment biopsies tended to underestimate the grade of the tumour. Based on these results, we conclude that pre-treatment biopsies are sufficiently accurate for differentiating low-grade from high-grade MCTs, regardless of biopsy technique or tumour location. © 2017 John Wiley & Sons Ltd.

  9. Open pit mining profit maximization considering selling stage and waste rehabilitation cost

    NASA Astrophysics Data System (ADS)

    Muttaqin, B. I. A.; Rosyidi, C. N.

    2017-11-01

    In open pit mining activities, determination of the cut-off grade becomes crucial for the company since the cut-off grade affects how much profit will be earned for the mining company. In this study, we developed a cut-off grade determination mode for the open pit mining industry considering the cost of mining, waste removal (rehabilitation) cost, processing cost, fixed cost, and selling stage cost. The main goal of this study is to develop a model of cut-off grade determination to get the maximum total profit. Secondly, this study is also developed to observe the model of sensitivity based on changes in the cost components. The optimization results show that the models can help mining company managers to determine the optimal cut-off grade and also estimate how much profit that can be earned by the mining company. To illustrate the application of the models, a numerical example and a set of sensitivity analysis are presented. From the results of sensitivity analysis, we conclude that the changes in the sales price greatly affects the optimal cut-off value and the total profit.

  10. Basic numerical competences in large-scale assessment data: Structure and long-term relevance.

    PubMed

    Hirsch, Stefa; Lambert, Katharina; Coppens, Karien; Moeller, Korbinian

    2018-03-01

    Basic numerical competences are seen as building blocks for later numerical and mathematical achievement. The current study aimed at investigating the structure of early numeracy reflected by different basic numerical competences in kindergarten and its predictive value for mathematical achievement 6 years later using data from large-scale assessment. This allowed analyses based on considerably large sample sizes (N > 1700). A confirmatory factor analysis indicated that a model differentiating five basic numerical competences at the end of kindergarten fitted the data better than a one-factor model of early numeracy representing a comprehensive number sense. In addition, these basic numerical competences were observed to reliably predict performance in a curricular mathematics test in Grade 6 even after controlling for influences of general cognitive ability. Thus, our results indicated a differentiated view on early numeracy considering basic numerical competences in kindergarten reflected in large-scale assessment data. Consideration of different basic numerical competences allows for evaluating their specific predictive value for later mathematical achievement but also mathematical learning difficulties. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Student and Faculty Perceptions of Plus/Minus Grading and Its Effect on Course Grade Point Averages

    ERIC Educational Resources Information Center

    Edgar, Leslie D.; Johnson, Donald M.; Graham, Donna L.; Dixon, Bruce L.

    2014-01-01

    In fall 2005, the Dale Bumpers College of Agricultural, Food and Life Sciences at the University of Arkansas authorized the optional use of a plus/minus grading system. Since 2005, approximately one-half of courses have been graded using plus/minus and one-half using the straight letter grade system. This study examined student (n = 338) and…

  12. Relationship of the Van Herick Grading System with Peripheral Iris Configuration and Level of Iris Insertion.

    PubMed

    Khan, Faisal Aziz; Niazi, Shafaq Pervez Khan; Khan, Assad Zaman

    2017-09-01

    To determine the relationship of the van Herick angle grading system with the level of iris insertion and peripheral iris configuration. Observational study. Eye department, Combined Military Hospital, Malir Cantt., Karachi, from May to October 2015. Sixty-five eyes of 65 patients were recruited. Anterior chamber depth at the temporal limbus was measured as a fraction of corneal section thickness using van Herick technique and graded on the standard 4-point scale of the van Herick grading system. Gonioscopy of the temporal quadrant was performed with a Posner 4 mirror goniolens and both the true level of iris insertion and peripheral iris configuration were recorded on a 4-point scale so as to equate with the van Herick 4-point grading system. Spearman's rho test was applied to determine the relationship of the van Herick grading system with level of iris root insertion and peripheral iris configuration. Amoderate positive correlation between van Herick grade and peripheral iris configuration was found which was statistically significant (rs=0.42, p < 0.001). Astatistically significant and moderate positive correlation was also detected between van Herick grade and the level of iris insertion (rs=0.45, p < 0.001). The van Herick grade has a moderately positive relationship with the peripheral iris configuration and true level of iris insertion.

  13. Are computer numerical control (CNC)-manufactured patient-specific metal templates available for posterior thoracic pedicle screw insertion? Feasibility and accuracy evaluation.

    PubMed

    Kong, Xiangxue; Tang, Lei; Ye, Qiang; Huang, Wenhua; Li, Jianyi

    2017-11-01

    Accurate and safe posterior thoracic pedicle insertion (PTPI) remains a challenge. Patient-specific drill templates (PDTs) created by rapid prototyping (RP) can assist in posterior thoracic pedicle insertion, but pose biocompatibility risks. The aims of this study were to develop alternative PDTs with computer numerical control (CNC) and assess their feasibility and accuracy in assisting PTPI. Preoperative CT images of 31 cadaveric thoracic vertebras were obtained and then the optimal pedicle screw trajectories were planned. The PDTs with optimal screw trajectories were randomly assigned to be designed and manufactured by CNC or RP in each vertebra. With the guide of the CNC- or RP-manufactured PDTs, the appropriate screws were inserted into the pedicles. Postoperative CT scans were performed to analyze any deviations at entry point and midpoint of the pedicles. The CNC group was found to be significant manufacture-time-shortening, and cost-decreasing, when compared with the RP group (P < 0.01). The PDTs fitted the vertebral laminates well while all screws were being inserted into the pedicles. There were no significant differences in absolute deviations at entry point and midpoint of the pedicle on either axial or sagittal planes (P > 0.05). The screw positions were grade 0 in 90.3% and grade 1 in 9.7% of the cases in the CNC group and grade 0 in 93.5% and grade 1 in 6.5% of the cases in the RP group (P = 0.641). CNC-manufactured PDTs are viable for assisting in PTPI with good feasibility and accuracy.

  14. The 2014 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma: Definition of Grading Patterns and Proposal for a New Grading System.

    PubMed

    Epstein, Jonathan I; Egevad, Lars; Amin, Mahul B; Delahunt, Brett; Srigley, John R; Humphrey, Peter A

    2016-02-01

    In November, 2014, 65 prostate cancer pathology experts, along with 17 clinicians including urologists, radiation oncologists, and medical oncologists from 19 different countries gathered in a consensus conference to update the grading of prostate cancer, last revised in 2005. The major conclusions were: (1) Cribriform glands should be assigned a Gleason pattern 4, regardless of morphology; (2) Glomeruloid glands should be assigned a Gleason pattern 4, regardless of morphology; (3) Grading of mucinous carcinoma of the prostate should be based on its underlying growth pattern rather than grading them all as pattern 4; and (4) Intraductal carcinoma of the prostate without invasive carcinoma should not be assigned a Gleason grade and a comment as to its invariable association with aggressive prostate cancer should be made. Regarding morphologies of Gleason patterns, there was clear consensus on: (1) Gleason pattern 4 includes cribriform, fused, and poorly formed glands; (2) The term hypernephromatoid cancer should not be used; (3) For a diagnosis of Gleason pattern 4, it needs to be seen at 10x lens magnification; (4) Occasional/seemingly poorly formed or fused glands between well-formed glands is insufficient for a diagnosis of pattern 4; (5) In cases with borderline morphology between Gleason pattern 3 and pattern 4 and crush artifacts, the lower grade should be favored; (6) Branched glands are allowed in Gleason pattern 3; (7) Small solid cylinders represent Gleason pattern 5; (8) Solid medium to large nests with rosette-like spaces should be considered to represent Gleason pattern 5; and (9) Presence of unequivocal comedonecrosis, even if focal is indicative of Gleason pattern 5. It was recognized by both pathologists and clinicians that despite the above changes, there were deficiencies with the Gleason system. The Gleason grading system ranges from 2 to 10, yet 6 is the lowest score currently assigned. When patients are told that they have a Gleason score 6 out of 10, it implies that their prognosis is intermediate and contributes to their fear of having a more aggressive cancer. Also, in the literature and for therapeutic purposes, various scores have been incorrectly grouped together with the assumption that they have a similar prognosis. For example, many classification systems consider Gleason score 7 as a single score without distinguishing 3+4 versus 4+3, despite studies showing significantly worse prognosis for the latter. The basis for a new grading system was proposed in 2013 by one of the authors (J.I.E.) based on data from Johns Hopkins Hospital resulting in 5 prognostically distinct Grade Groups. This new system was validated in a multi-institutional study of over 20,000 radical prostatectomy specimens, over 16,000 needle biopsy specimens, and over 5,000 biopsies followed by radiation therapy. There was broad (90%) consensus for the adoption of this new prostate cancer Grading system in the 2014 consensus conference based on: (1) the new classification provided more accurate stratification of tumors than the current system; (2) the classification simplified the number of grading categories from Gleason scores 2 to 10, with even more permutations based on different pattern combinations, to Grade Groups 1 to 5; (3) the lowest grade is 1 not 6 as in Gleason, with the potential to reduce overtreatment of indolent cancer; and (4) the current modified Gleason grading, which forms the basis for the new grade groups, bears little resemblance to the original Gleason system. The new grades would, for the foreseeable future, be used in conjunction with the Gleason system [ie. Gleason score 3+3=6 (Grade Group 1)]. The new grading system and the terminology Grade Groups 1-5 have also been accepted by the World Health Organization for the 2016 edition of Pathology and Genetics: Tumours of the Urinary System and Male Genital Organs.

  15. The World Health Organization 1973 classification system for grade is an important prognosticator in T1 non-muscle-invasive bladder cancer.

    PubMed

    van de Putte, Elisabeth E Fransen; Bosschieter, Judith; van der Kwast, Theo H; Bertz, Simone; Denzinger, Stefan; Manach, Quentin; Compérat, Eva M; Boormans, Joost L; Jewett, Michael A S; Stoehr, Robert; van Leenders, Geert J L H; Nieuwenhuijzen, Jakko A; Zlotta, Alexandre R; Hendricksen, Kees; Rouprêt, Morgan; Otto, Wolfgang; Burger, Maximilian; Hartmann, Arndt; van Rhijn, Bas W G

    2018-04-10

    To compare the prognostic value of the World Health Organization (WHO) 1973 and 2004 classification systems for grade in T1 bladder cancer (T1-BC), as both are currently recommended in international guidelines. Three uro-pathologists re-revised slides of 601 primary (first diagnosis) T1-BCs, initially managed conservatively (bacille Calmette-Guérin) in four hospitals. Grade was defined according to WHO1973 (Grade 1-3) and WHO2004 (low-grade [LG] and high-grade [HG]). This resulted in a lack of Grade 1 tumours, 188 (31%) Grade 2, and 413 (69%) Grade 3 tumours. There were 47 LG (8%) vs 554 (92%) HG tumours. We determined the prognostic value for progression-free survival (PFS) and cancer-specific survival (CSS) in Cox-regression models and corrected for age, sex, multiplicity, size and concomitant carcinoma in situ. At a median follow-up of 5.9 years, 148 patients showed progression and 94 died from BC. The WHO1973 Grade 3 was negatively associated with PFS (hazard ratio [HR] 2.1) and CSS (HR 3.4), whilst WHO2004 grade was not prognostic. On multivariable analysis, WHO1973 grade was the only prognostic factor for progression (HR 2.0). Grade 3 tumours (HR 3.0), older age (HR 1.03) and tumour size >3 cm (HR 1.8) were all independently associated with worse CSS. The WHO1973 classification system for grade has strong prognostic value in T1-BC, compared to the WHO2004 system. Our present results suggest that WHO1973 grade cannot be replaced by the WHO2004 classification in non-muscle-invasive BC guidelines. © 2018 The Authors BJU International © 2018 BJU International Published by John Wiley & Sons Ltd.

  16. Systematic Evaluation of Salt Cavern Well Integrity

    NASA Astrophysics Data System (ADS)

    Roberts, B. L.; Lord, D. L.; Lord, A. S.; Bettin, G.; Sobolik, S. R.; Park, B. Y.

    2017-12-01

    The U.S. Strategic Petroleum Reserve (SPR) holds a reserve of crude oil ( 700 million barrels) to help ease any interruptions in oil import to the United States. The oil is stored in a set of 63 underground caverns distributed across four sites along the U.S. Gulf Coast. The caverns were solution mined into salt domes at each of the four sites. The plastic nature of the salt is beneficial for the storage of crude oil as it heals any fractures that may occur in the salt. The SPR is responsible for operating and maintaining the nearly 120 wells used to access the storage caverns over operational lifetimes spanning decades. Salt creep can induce deformation of the well casing which must be remediated to insure cavern and well integrity. This is particularly true at the interface between the plastic salt and the rigid caprock. The Department of Energy, the SPR Management and Operations contractor, and Sandia National Laboratories has developed a multidimensional well-grading system for the salt cavern access wells. This system is designed to assign numeric grades to each well indicating its risk of losing integrity and remediation priority. The system consists of several main components which themselves may consist of sub-components. The main components consider such things as salt cavern pressure history, results from geomechanical simulations modeling salt deformation, and measurements of well casing deformation due to salt creep. In addition, the geology of the salt domes and their overlying caprock is also included in the grading. These multiple factors are combined into summary values giving the monitoring and remediation priority for each well. Sandia National Laboratories is a multimission laboratory managed and operated by National Technology and Engineering Solutions of Sandia LLC, a wholly owned subsidiary of Honeywell International Inc. for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-NA0003525.

  17. Inventing Graphing: Meta-Representational Expertise in Children.

    ERIC Educational Resources Information Center

    DiSessa, Andra A.; And Others

    1991-01-01

    A cooperative activity involving eight sixth grade students over five days focused on inventing static representations of motion. In generating, critiquing and refining numerous representations, strong metarepresentational competence was found. An intricate blend of the children's conceptual and interactional skills, their interest in and sense of…

  18. Mathematics. Exceptional Child Education Curriculum K-12.

    ERIC Educational Resources Information Center

    Jordon, Thelma; And Others

    The mathematics curriculum provides a framework of instruction for exceptional child education in grades K-12. Content areas include: numeration, whole numbers, rational numbers, real/complex numbers, calculator literacy, measurement, geometry, statistics, functions/relations, computer literacy, and pre-algebra. The guide is organized by content…

  19. Neuropathic pain: an updated grading system for research and clinical practice.

    PubMed

    Finnerup, Nanna B; Haroutounian, Simon; Kamerman, Peter; Baron, Ralf; Bennett, David L H; Bouhassira, Didier; Cruccu, Giorgio; Freeman, Roy; Hansson, Per; Nurmikko, Turo; Raja, Srinivasa N; Rice, Andrew S C; Serra, Jordi; Smith, Blair H; Treede, Rolf-Detlef; Jensen, Troels S

    2016-08-01

    The redefinition of neuropathic pain as "pain arising as a direct consequence of a lesion or disease affecting the somatosensory system," which was suggested by the International Association for the Study of Pain (IASP) Special Interest Group on Neuropathic Pain (NeuPSIG) in 2008, has been widely accepted. In contrast, the proposed grading system of possible, probable, and definite neuropathic pain from 2008 has been used to a lesser extent. Here, we report a citation analysis of the original NeuPSIG grading paper of 2008, followed by an analysis of its use by an expert panel and recommendations for an improved grading system. As of February, 2015, 608 eligible articles in Scopus cited the paper, 414 of which cited the neuropathic pain definition. Of 220 clinical studies citing the paper, 56 had used the grading system. The percentage using the grading system increased from 5% in 2009 to 30% in 2014. Obstacles to a wider use of the grading system were identified, including (1) questions about the relative significance of confirmatory tests, (2) the role of screening tools, and (3) uncertainties about what is considered a neuroanatomically plausible pain distribution. Here, we present a revised grading system with an adjusted order, better reflecting clinical practice, improvements in the specifications, and a word of caution that even the "definite" level of neuropathic pain does not always indicate causality. In addition, we add a table illustrating the area of pain and sensory abnormalities in common neuropathic pain conditions and propose areas for further research.

  20. Quantification of human responses

    NASA Technical Reports Server (NTRS)

    Steinlage, R. C.; Gantner, T. E.; Lim, P. Y. W.

    1992-01-01

    Human perception is a complex phenomenon which is difficult to quantify with instruments. For this reason, large panels of people are often used to elicit and aggregate subjective judgments. Print quality, taste, smell, sound quality of a stereo system, softness, and grading Olympic divers and skaters are some examples of situations where subjective measurements or judgments are paramount. We usually express what is in our mind through language as a medium but languages are limited in available choices of vocabularies, and as a result, our verbalizations are only approximate expressions of what we really have in mind. For lack of better methods to quantify subjective judgments, it is customary to set up a numerical scale such as 1, 2, 3, 4, 5 or 1, 2, 3, ..., 9, 10 for characterizing human responses and subjective judgments with no valid justification except that these scales are easy to understand and convenient to use. But these numerical scales are arbitrary simplifications of the complex human mind; the human mind is not restricted to such simple numerical variations. In fact, human responses and subjective judgments are psychophysical phenomena that are fuzzy entities and therefore difficult to handle by conventional mathematics and probability theory. The fuzzy mathematical approach provides a more realistic insight into understanding and quantifying human responses. This paper presents a method for quantifying human responses and subjective judgments without assuming a pattern of linear or numerical variation for human responses. In particular, quantification and evaluation of linguistic judgments was investigated.

  1. Grading Practices and Distributions Across Internal Medicine Clerkships.

    PubMed

    Fazio, Sara B; Torre, Dario M; DeFer, Thomas M

    2016-01-01

    Clerkship evaluation and grading practices vary widely between U.S. medical schools. Grade inflation continues to exist, and grade distribution is likely to be different among U.S. medical schools. Increasing the number of available grades curtails "grade inflation." A national survey of all Clerkship Directors in Internal Medicine members was administered in 2011. The authors assessed key aspects of grading. Response rate was 76%. Among clerkship directors (CDs), 61% of respondents agreed that grade inflation existed in the internal medicine clerkship at their school, and 43% believed that it helped students obtain better residency positions. With respect to grading practices, 79% of CDs define specific behaviors needed to achieve each grade, and 36% specify an ideal grade distribution. In addition, 44% have a trained core faculty responsible for evaluating students, 35% describe formal grading meetings, and 39% use the Reporter-Interpreter-Manager-Educator (RIME) scheme. Grading scales were described as follows: 4% utilize a pass/fail system, 13% a 3-tier (e.g., Honors/Pass/Fail), 45% 4-tier, 35% 5-tier, and 4% 6+-tier system. There was a trend to higher grades with more tiers available. Grade inflation continues in the internal medicine clerkship. Almost half of CDs feel that this practice assists students to obtain better residency positions. A minority of programs have a trained core faculty who are responsible for evaluation. About one third have formal grading meetings and use the RIME system; both have been associated with more robust and balanced grading practices. In particular, there is a wide variation between schools in the percentage of students who are awarded the highest grade, which has implications for residency applications. Downstream users of clinical clerkship grades must be fully aware of these variations in grading in order to appropriately judge medical student performance.

  2. On-line prediction of yield grade, longissimus muscle area, preliminary yield grade, adjusted preliminary yield grade, and marbling score using the MARC beef carcass image analysis system.

    PubMed

    Shackelford, S D; Wheeler, T L; Koohmaraie, M

    2003-01-01

    The present experiment was conducted to evaluate the ability of the U.S. Meat Animal Research Center's beef carcass image analysis system to predict calculated yield grade, longissimus muscle area, preliminary yield grade, adjusted preliminary yield grade, and marbling score under commercial beef processing conditions. In two commercial beef-processing facilities, image analysis was conducted on 800 carcasses on the beef-grading chain immediately after the conventional USDA beef quality and yield grades were applied. Carcasses were blocked by plant and observed calculated yield grade. The carcasses were then separated, with 400 carcasses assigned to a calibration data set that was used to develop regression equations, and the remaining 400 carcasses assigned to a prediction data set used to validate the regression equations. Prediction equations, which included image analysis variables and hot carcass weight, accounted for 90, 88, 90, 88, and 76% of the variation in calculated yield grade, longissimus muscle area, preliminary yield grade, adjusted preliminary yield grade, and marbling score, respectively, in the prediction data set. In comparison, the official USDA yield grade as applied by online graders accounted for 73% of the variation in calculated yield grade. The technology described herein could be used by the beef industry to more accurately determine beef yield grades; however, this system does not provide an accurate enough prediction of marbling score to be used without USDA grader interaction for USDA quality grading.

  3. Investigation of the effects of graded models on the biomechanical behavior of a bone-dental implant system under osteoporotic conditions

    PubMed Central

    Li, Ying; Shuang Liu, Zhong; Ming Bai, Xiao; Zhang, Bin

    2013-01-01

    Objective: To investigate the effects of graded models on the biomechanical behavior of a bone-implant system under osteoporotic conditions. Methodology : A finite element model (FEM) of the jawbone segments with a titanium implant is used. Two types of models (a graded model and a non-graded model) are established. The graded model is established based on the graded variation of the elastic modulus of the cortical bone and the non-graded model is defined by homogeneous cortical bone. The vertical and oblique loads are adopted. The max von Mises stresses and the max displacements of the cortical bone are evaluated. Results: Comparing the two types of models, the difference in the maximum von Mises stresses of the cortical bone is more than 20%. The values of the maximum displacements in the graded models are considerably less than in the non-graded models. Conclusions: These results indicate the significance of taking into account the actual graded properties of the cortical bone so that the biomechanical behavior of the bone-implant system can be analyzed accurately. PMID:24353590

  4. Investigation of the effects of graded models on the biomechanical behavior of a bone-dental implant system under osteoporotic conditions.

    PubMed

    Li, Ying; Shuang Liu, Zhong; Ming Bai, Xiao; Zhang, Bin

    2013-04-01

    To investigate the effects of graded models on the biomechanical behavior of a bone-implant system under osteoporotic conditions. Methodology : A finite element model (FEM) of the jawbone segments with a titanium implant is used. Two types of models (a graded model and a non-graded model) are established. The graded model is established based on the graded variation of the elastic modulus of the cortical bone and the non-graded model is defined by homogeneous cortical bone. The vertical and oblique loads are adopted. The max von Mises stresses and the max displacements of the cortical bone are evaluated. Comparing the two types of models, the difference in the maximum von Mises stresses of the cortical bone is more than 20%. The values of the maximum displacements in the graded models are considerably less than in the non-graded models. These results indicate the significance of taking into account the actual graded properties of the cortical bone so that the biomechanical behavior of the bone-implant system can be analyzed accurately.

  5. The Effects of Framing Grades on Student Learning and Preferences

    ERIC Educational Resources Information Center

    Bies-Hernandez, Nicole J.

    2012-01-01

    Two experiments examined whether framing effects, in terms of losses and gains, can be extended to student learning and grading preferences. In Experiment 1, participants rated psychology course syllabi to investigate preferences for differently framed grading systems: a loss versus gain grading system. The results showed a clear framing effect…

  6. Systematic Review of Anastomotic Leakage Rate According to an International Grading System Following Anterior Resection for Rectal Cancer

    PubMed Central

    Ye, Guang-Yao; Yu, Min-Hao; Gao, Yun-He; Li, Zhao-Shen; Yu, En-Da; Zhong, Ming

    2013-01-01

    Background A generally acceptable definition and a severity grading system for anastomotic leakages (ALs) following rectal resection were not available until 2010, when the International Study Group of Rectal Cancer (ISGRC) proposed a definition and a grading system for AL. Methods A search for published data was performed using the MEDLINE database (2000 to December 5, 2012) to perform a systematic review of the studies that described AL, grade AL according to the grading system, pool data, and determine the average rate of AL for each grade after anterior resection (AR) for rectal cancer. Results A total of 930 abstracts were retrieved; 40 articles on AR, 25 articles on low AR (LAR), and 5 articles on ultralow AR (ULAR) were included in the review and analysis. The pooled overall AL rate of AR was 8.58% (2,085/24,288); the rate of the asymptomatic leakage (Grade A) was 2.57%, that of AL that required active intervention without relaparotomy (Grade B) was 2.37%, and that of AL that required relaparotomy (Grade C) was 5.40%. The pooled rate of AL that required relaparotomy was higher in AR (5.40%) than in LAR (4.70%) and in ULAR (1.81%), which could be attributed to the higher rate of protective defunctioning stoma in LAR (40.72%) and ULAR (63.44%) compared with that in AR (30.11%). Conclusions The new grading system is simple that the ALs of each grade can be easily extracted from past publications, therefore likely to be accepted and applied in future studies. PMID:24086552

  7. Automated Grading of Rough Hardwood Lumber

    Treesearch

    Richard W. Conners; Tai-Hoon Cho; Philip A. Araman

    1989-01-01

    Any automatic hardwood grading system must have two components. The first of these is a computer vision system for locating and identifying defects on rough lumber. The second is a system for automatically grading boards based on the output of the computer vision system. This paper presents research results aimed at developing the first of these components. The...

  8. Independent validation of the prognostic capacity of the ISUP prostate cancer grade grouping system for radiation treated patients with long-term follow-up.

    PubMed

    Spratt, D E; Jackson, W C; Abugharib, A; Tomlins, S A; Dess, R T; Soni, P D; Lee, J Y; Zhao, S G; Cole, A I; Zumsteg, Z S; Sandler, H; Hamstra, D; Hearn, J W; Palapattu, G; Mehra, R; Morgan, T M; Feng, F Y

    2016-09-01

    There has been a recent proposal to change the grading system of prostate cancer into a five-tier grade grouping system. The prognostic impact of this has been demonstrated in regards only to biochemical recurrence-free survival (bRFS) with short follow-up (3 years). Between 1990 and 2013, 847 consecutive men were treated with definitive external beam radiation therapy at a single academic center. To validate the new grade grouping system, bRFS, distant metastases-free survival (DMFS) and prostate cancer-specific survival (PCSS) were calculated. Adjusted Kaplan-Meier and multivariable Cox regression analyses were performed to assess the independent impact of the new grade grouping system. Discriminatory analyses were performed to compare the commonly used three-tier Gleason score system (6, 7 and 8-10) to the new system. The median follow-up of our cohort was 88 months. The 5-grade groups independently validated differing risks of bRFS (group 1 as reference; adjusted hazard ratio (aHR) 1.35, 2.16, 1.79 and 3.84 for groups 2-5, respectively). Furthermore, a clear stratification was demonstrated for DMFS (aHR 2.03, 3.18, 3.62 and 13.77 for groups 2-5, respectively) and PCSS (aHR 3.00, 5.32, 6.02 and 39.02 for groups 2-5, respectively). The 5-grade group system had improved prognostic discrimination for all end points compared with the commonly used three-tiered system (that is, Gleason score 6, 7 and 8-10). In a large independent radiotherapy cohort with long-term follow-up, we have validated the bRFS benefit of the proposed five-tier grade grouping system. Furthermore, we have demonstrated that the system is highly prognostic for DMFS and PCSS. Grade group 5 had markedly worse outcomes for all end points, and future work is necessary to improve outcomes in these patients.

  9. Independent surgical validation of the new prostate cancer grade-grouping system.

    PubMed

    Spratt, Daniel E; Cole, Adam I; Palapattu, Ganesh S; Weizer, Alon Z; Jackson, William C; Montgomery, Jeffrey S; Dess, Robert T; Zhao, Shuang G; Lee, Jae Y; Wu, Angela; Kunju, Lakshmi P; Talmich, Emily; Miller, David C; Hollenbeck, Brent K; Tomlins, Scott A; Feng, Felix Y; Mehra, Rohit; Morgan, Todd M

    2016-11-01

    To report the independent prognostic impact of the new prostate cancer grade-grouping system in a large external validation cohort of patients treated with radical prostatectomy (RP). Between 1994 and 2013, 3 694 consecutive men were treated with RP at a single institution. To investigate the performance of and validate the grade-grouping system, biochemical recurrence-free survival (bRFS) rates were assessed using Kaplan-Meier tests, Cox-regression modelling, and discriminatory comparison analyses. Separate analyses were performed based on biopsy and RP grade. The median follow-up was 52.7 months. The 5-year actuarial bRFS for biopsy grade groups 1-5 were 94.2%, 89.2%, 73.1%, 63.1%, and 54.7%, respectively (P < 0.001). Similarly, the 5-year actuarial bRFS based on RP grade groups was 96.1%, 93.0%, 74.0%, 64.4%, and 49.9% for grade groups 1-5, respectively (P < 0.001). The adjusted hazard ratios for bRFS relative to biopsy grade group 1 were 1.98, 4.20, 5.57, and 9.32 for groups 2, 3, 4, and 5, respectively (P < 0.001), and for RP grade groups were 2.09, 5.27, 5.86, and 10.42 (P < 0.001). The five-grade-group system had a higher prognostic discrimination compared with the commonly used three-tier system (Gleason score 6 vs 7 vs 8-10). In an independent surgical cohort, we have validated the prognostic benefit of the new prostate cancer grade-grouping system for bRFS, and shown that the benefit is maintained after adjusting for important clinicopathological variables. The greater predictive accuracy of the new system will improve risk stratification in the clinical setting and aid in patient counselling. © 2016 The Authors BJU International © 2016 BJU International Published by John Wiley & Sons Ltd.

  10. Prospective validation of a surgical complications grading system in a cohort of 2114 patients.

    PubMed

    Mazeh, Haggi; Cohen, Oded; Mizrahi, Ido; Hamburger, Tamar; Stojadinovic, Alexander; Abu-Wasel, Bassam; Alaiyan, Bilal; Freund, Herbert R; Eid, Ahmed; Nissan, Aviram

    2014-05-01

    We recently reported a grading system for surgical complications. This system proved to have a high sensitivity for recording minor but meaningful complications prolonging hospital stay in patients after colorectal surgery. We aimed to prospectively validate the complication grading system in a general surgery department over 1 year. All surgical procedures and related complications were prospectively recorded between January 1st and December 31st, 2009. Surgical complications were graded on a severity scale of 1-5. The system classifies short-term outcome by grade emphasizing intensity of therapy required for treatment of the defined complication. During the study period, 2114 patients underwent surgery. Elective and oncological surgeries were performed in 1606 (76%) and 465 (22%) patients, respectively. There were 422 surgical complications in 304 (14%) patients (Grade 1/2: 203 [67%]; Grade 3/4: 90 [29%]; Grade 5: 11 [4%]). Median length of stay correlated significantly with complication severity: 2.3 d for no complication, 6.2 and 11.8 d for Grades 1/2 and 3/4, respectively (P < 0.001). Older age (OR 2.75, P < 0.001), comorbidities (OR 1.44, P = 0.02), American Society of Anesthesiology score >2 (OR 2.07, P < 0.001), contamination Grade (OR 1.85, P = 0.001), oncological (OR 2.82, P < 0.001), open (OR 1.22, P = 0.03), prolonged >120 min (OR 2.08, P < 0.001), and emergency surgery (OR 1.42, P = 0.02) independently predicted postoperative complications. This system of grading surgical complications permits standardized reporting of surgical morbidity according to the severity of impact. Prospective validation of this system supports its use in a general surgery setting as a tool for surgical outcome assessment and quality assurance. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. An empirical study of the predictive validity of number grades in medical school using 3 decades of longitudinal data: implications for a grading system.

    PubMed

    Gonnella, Joseph S; Erdmann, James B; Hojat, Mohammadreza

    2004-04-01

    Context It is important to establish the predictive validity of medical school grades. The strength of predictive validity and the ability to identify at-risk students in medical schools depends upon assessment systems such as number grades, pass/fail (P/F) or honours/pass/fail (H/P/F) systems. Objective This study was designed to examine the predictive validity of number grades in medical school, and to determine whether any important information is lost in a shift from number to P/F and H/P/F grading systems. Subjects The participants in this prospective, longitudinal study were 6656 medical students who studied at Jefferson Medical College over 3 decades. They were grouped into 10 deciles based on their number grades in Year 1 of medical school. Methods Participants were compared on academic accomplishments in Years 2 and 3 of medical school, medical school class rank, delayed graduation and attrition, performance on medical licensing examinations and clinical competence ratings in the first postgraduate year. Results Results supported the short- and longterm predictive validity of the number grades. Ratings of clinical competence beyond medical school were predicted by number grades in medical school. We demonstrated that small differences in number grades are statistically meaningful, and that important information for identifying students in need of remedial education is lost when students who narrowly meet faculty's expectations are included with the rest of the class in a broad 'pass' category. Conclusions The findings refute the argument that knowledge of sciences basic to medicine is not critical to subsequent performance in medical school and beyond if an appropriate evaluation system is used. Furthermore, the results of this study raise questions about abandoning number grades in favour of a pass/fail system. Consideration of these findings in policy decisions regarding assessment systems of medical students is recommended.

  12. Development and characterization of food-grade tracers for the global grain tracing and recall system.

    PubMed

    Lee, Kyung-Min; Armstrong, Paul R; Thomasson, J Alex; Sui, Ruixiu; Casada, Mark; Herrman, Timothy J

    2010-10-27

    Tracing grain from the farm to its final processing destination as it moves through multiple grain-handling systems, storage bins, and bulk carriers presents numerous challenges to existing record-keeping systems. This study examines the suitability of coded caplets to trace grain, in particular, to evaluate methodology to test tracers' ability to withstand the rigors of a commercial grain handling and storage systems as defined by physical properties using measurement technology commonly applied to assess grain hardness and end-use properties. Three types of tracers to dispense into bulk grains for tracing the grain back to its field of origin were developed using three food-grade substances [processed sugar, pregelatinized starch, and silicified microcrystalline cellulose (SMCC)] as a major component in formulations. Due to a different functionality of formulations, the manufacturing process conditions varied for each tracer type, resulting in unique variations in surface roughness, weight, dimensions, and physical and spectroscopic properties before and after coating. The applied two types of coating [pregelatinized starch and hydroxypropylmethylcellulose (HPMC)] using an aqueous coating system containing appropriate plasticizers showed uniform coverage and clear coating. Coating appeared to act as a barrier against moisture penetration, to protect against mechanical damage of the surface of the tracers, and to improve the mechanical strength of tracers. The results of analysis of variance (ANOVA) tests showed the type of tracer, coating material, conditioning time, and a theoretical weight gain significantly influenced the morphological and physical properties of tracers. Optimization of these factors needs to be pursued to produce desirable tracers with consistent quality and performance when they flow with bulk grains throughout the grain marketing channels.

  13. 49 CFR 212.231 - Highway-rail grade crossing inspector.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Control Devices; and (6) Knowledge of railroad signal systems sufficient to ensure that highway-rail grade... signal systems. (d) A State signal and train control inspector qualified under this part and who has... independent inspections of all types of highway-rail grade crossing warning systems for the purpose of...

  14. 49 CFR 212.231 - Highway-rail grade crossing inspector.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Control Devices; and (6) Knowledge of railroad signal systems sufficient to ensure that highway-rail grade... signal systems. (d) A State signal and train control inspector qualified under this part and who has... independent inspections of all types of highway-rail grade crossing warning systems for the purpose of...

  15. Grading System and Student Effort

    ERIC Educational Resources Information Center

    Paredes, Valentina

    2017-01-01

    Several papers have proposed that the grading system affects students' incentives to exert effort. In particular, the previous literature has compared student effort under relative and absolute grading systems, but the results are mixed and the implications of the models have not been empirically tested. In this paper, I build a model where…

  16. Complex and elementary histological scoring systems for articular cartilage repair.

    PubMed

    Orth, Patrick; Madry, Henning

    2015-08-01

    The repair of articular cartilage defects is increasingly moving into the focus of experimental and clinical investigations. Histological analysis is the gold standard for a valid and objective evaluation of cartilaginous repair tissue and predominantly relies on the use of established scoring systems. In the past three decades, numerous elementary and complex scoring systems have been described and modified, including those of O'Driscoll, Pineda, Wakitani, Sellers and Fortier for entire defects as well as those according to the International Cartilage Repair Society (ICRS-I/II) for osteochondral tissue biopsies. Yet, this coexistence of different grading scales inconsistently addressing diverse parameters may impede comparability between reported study outcomes. Furthermore, validation of these histological scoring systems has only seldom been performed to date. The aim of this review is (1) to give a comprehensive overview and to compare the most important established histological scoring systems for articular cartilage repair, (2) to describe their specific advantages and pitfalls, and (3) to provide valid recommendations for their use in translational and clinical studies of articular cartilage repair.

  17. Revisions of the Learning Mastery Systems for the Harper and Row Grades One and Two and the Macmillan Bank Street Grade One Reading Series.

    ERIC Educational Resources Information Center

    Maeder, Jacqueline; And Others

    The revisions on the Learning Mastery Systems (LMSs) for the Harper & Row grade-one and grade-two and the Macmillan Bank Street grade-one reading programs are outlined in this document. A rationale for the revisions is presented. An LMS is a set of materials and procedures prepared by the southwest Regional Laboratory (SWRL) as an…

  18. A note on the solutions of some nonlinear equations arising in third-grade fluid flows: an exact approach.

    PubMed

    Aziz, Taha; Mahomed, F M

    2014-01-01

    In this communication, we utilize some basic symmetry reductions to transform the governing nonlinear partial differential equations arising in the study of third-grade fluid flows into ordinary differential equations. We obtain some simple closed-form steady-state solutions of these reduced equations. Our solutions are valid for the whole domain [0,∞) and also satisfy the physical boundary conditions. We also present the numerical solutions for some of the underlying equations. The graphs corresponding to the essential physical parameters of the flow are presented and discussed.

  19. Closed Form Solutions for Unsteady Free Convection Flow of a Second Grade Fluid over an Oscillating Vertical Plate

    PubMed Central

    Ali, Farhad; Khan, Ilyas; Shafie, Sharidan

    2014-01-01

    Closed form solutions for unsteady free convection flows of a second grade fluid near an isothermal vertical plate oscillating in its plane using the Laplace transform technique are established. Expressions for velocity and temperature are obtained and displayed graphically for different values of Prandtl number Pr, thermal Grashof number Gr, viscoelastic parameter α, phase angle ωτ and time τ. Numerical values of skin friction τ 0 and Nusselt number Nu are shown in tables. Some well-known solutions in literature are reduced as the limiting cases of the present solutions. PMID:24551033

  20. Graded bit patterned magnetic arrays fabricated via angled low-energy He ion irradiation.

    PubMed

    Chang, L V; Nasruallah, A; Ruchhoeft, P; Khizroev, S; Litvinov, D

    2012-07-11

    A bit patterned magnetic array based on Co/Pd magnetic multilayers with a binary perpendicular magnetic anisotropy distribution was fabricated. The binary anisotropy distribution was attained through angled helium ion irradiation of a bit edge using hydrogen silsesquioxane (HSQ) resist as an ion stopping layer to protect the rest of the bit. The viability of this technique was explored numerically and evaluated through magnetic measurements of the prepared bit patterned magnetic array. The resulting graded bit patterned magnetic array showed a 35% reduction in coercivity and a 9% narrowing of the standard deviation of the switching field.

  1. Optimizing photophoresis and asymmetric force fields for grading of Brownian particles.

    PubMed

    Neild, Adrian; Ng, Tuck Wah; Woods, Timothy

    2009-12-10

    We discuss a scheme that incorporates restricted spatial input location, orthogonal sort, and movement direction features, with particle sorting achieved by using an asymmetric potential cycled on and off, while movement is accomplished by photophoresis. Careful investigation has uncovered the odds of sorting between certain pairs of particle sizes to be solely dependent on radii in each phase of the process. This means that the most effective overall sorting can be achieved by maximizing the number of phases. This optimized approach is demonstrated using numerical simulation to permit grading of a range of nanometer-scale particle sizes.

  2. A Note on the Solutions of Some Nonlinear Equations Arising in Third-Grade Fluid Flows: An Exact Approach

    PubMed Central

    Mahomed, F. M.

    2014-01-01

    In this communication, we utilize some basic symmetry reductions to transform the governing nonlinear partial differential equations arising in the study of third-grade fluid flows into ordinary differential equations. We obtain some simple closed-form steady-state solutions of these reduced equations. Our solutions are valid for the whole domain [0,∞) and also satisfy the physical boundary conditions. We also present the numerical solutions for some of the underlying equations. The graphs corresponding to the essential physical parameters of the flow are presented and discussed. PMID:25143962

  3. Temperature distributions and thermal stresses in a graded zirconia/metal gas path seal system for aircraft gas turbine engines

    NASA Technical Reports Server (NTRS)

    Taylor, C. M.; Bill, R. C.

    1978-01-01

    A ceramic/metallic aircraft gas turbine outer gas path seal designed for improved engine performance was studied. Transient temperature and stress profiles in a test seal geometry were determined by numerical analysis. During a simulated engine deceleration cycle from sea-level takeoff to idle conditions, the maximum seal temperature occurred below the seal surface, therefore the top layer of the seal was probably subjected to tensile stresses exceeding the modulus of rupture. In the stress analysis both two- and three-dimensional finite element computer programs were used. Predicted trends of the simpler and more easily usable two-dimensional element programs were borne out by the three-dimensional finite element program results.

  4. Quantification of Fibrosis and Osteosclerosis in Myeloproliferative Neoplasms: A Computer-Assisted Image Study

    PubMed Central

    Teman, Carolin J.; Wilson, Andrew R.; Perkins, Sherrie L.; Hickman, Kimberly; Prchal, Josef T.; Salama, Mohamed E.

    2010-01-01

    Evaluation of bone marrow fibrosis and osteosclerosis in myeloproliferative neoplasms (MPN) is subject to interobserver inconsistency. Performance data for currently utilized fibrosis grading systems are lacking, and classification scales for osteosclerosis do not exist. Digital imaging can serve as a quantification method for fibrosis and osteosclerosis. We used digital imaging techniques for trabecular area assessment and reticulin-fiber quantification. Patients with all Philadelphia negative MPN subtypes had higher trabecular volume than controls (p ≤0.0015). Results suggest that the degree of osteosclerosis helps differentiate primary myelofibrosis from other MPN. Numerical quantification of fibrosis highly correlated with subjective scores, and interobserver correlation was satisfactory. Digital imaging provides accurate quantification for osteosclerosis and fibrosis. PMID:20122729

  5. [Treatment of idiopathic varicocele: comparative study of three techniques about 128 cases].

    PubMed

    Khouni, Hassen; Bouchiba, Nizar; Khelifa, Melik Melek; Ben Ali, Moez; Sebai, Akrem; Dali, Meriem; Charfi, Mehdi; Chouchene, Adnene; El Kateb, Faycel; Bouhaouala, Habib; Balti, Med Hedi

    2011-12-01

    Several modalities of varicocele treatment are available, however, no therapeutic technique showed its superiority with regard to the other one. To compare the results of three techniques of varicocelecomy. Retrospective Analytical and comparative study of 128 patients treated by of three techniques of varicocelectomy: the open surgery by retro peritoneal way for 42 patients (GI), the varicocelectomie coelioscopique for 41 patients (GII) and the antegrade scrotal sclerotherapy done for 45 patients (GIII), between march 2001 and January 2009.The mean age was 28 years. The main motive for consultation was represented by the painful varicocele in 67 % of the cases, followed by the hypofertility in 20.3 % of the cases and the association both in 12,5 % of the cases. The varicocele was in leftsider in 71.1 % of the cases, to the right side in 5.4 % of the cases and was bilateral in 23.43 % of the cases. Varicocele was infra-clinical at 6 patients, grade 1 in 16 sides, grade 2 in 105 sides and grade 3 in 31 sides. The numeration, the mobility as well as the morphology of sperm cells were comparable between the three groups Results: The global rate success was 81.2 %, with the highest rate found in the group III which was treated by antégrade scrotal sclerotherapy (84.4 %). The improvement of the parameters of the spermogramme was noted in the three groups, however a statistically significant difference was found only in patients treated by antégrade scrotal sclerotherapy; it mainly concerned numeration and the mobility of spermatozoides. The highest rate of pregnancy was recorded in patients treated by antégrade scrotal sclerotherapy (13.3%). The main postoperative complications were hydrocele (16%) followed by testicular hypotrophy (3 patients). Three techniques of varicocele treatment, offer either a similar success rate, and improvement of parameters of the sperm cells. However, antegrade scrotal sclerotherpy seem to be the best treatment of first intention in proposed, regarding its efficiency, of the ease of its realization, its moderate cost and its feasibility in case of recurrence if varicocele was treated with open way'GIII).

  6. Object-oriented approach for gas turbine engine simulation

    NASA Technical Reports Server (NTRS)

    Curlett, Brian P.; Felder, James L.

    1995-01-01

    An object-oriented gas turbine engine simulation program was developed. This program is a prototype for a more complete, commercial grade engine performance program now being proposed as part of the Numerical Propulsion System Simulator (NPSS). This report discusses architectural issues of this complex software system and the lessons learned from developing the prototype code. The prototype code is a fully functional, general purpose engine simulation program, however, only the component models necessary to model a transient compressor test rig have been written. The production system will be capable of steady state and transient modeling of almost any turbine engine configuration. Chief among the architectural considerations for this code was the framework in which the various software modules will interact. These modules include the equation solver, simulation code, data model, event handler, and user interface. Also documented in this report is the component based design of the simulation module and the inter-component communication paradigm. Object class hierarchies for some of the code modules are given.

  7. Design of elliptical-core mode-selective photonic lanterns with six modes for MIMO-free mode division multiplexing systems.

    PubMed

    Sai, Xiaowei; Li, Yan; Yang, Chen; Li, Wei; Qiu, Jifang; Hong, Xiaobin; Zuo, Yong; Guo, Hongxiang; Tong, Weijun; Wu, Jian

    2017-11-01

    Elliptical-core few mode fiber (EC-FMF) is used in a mode division multiplexing (MDM) transmission system to release multiple-input-multiple-output (MIMO) digital-signal-processing, which reduces the cost and the complexity of the receiver. However, EC-FMF does not match with conventional multiplexers/de-multiplexers (MUXs/DeMUXs) such as a photonic lantern, leading to extra mode coupling loss and crosstalk. We design elliptical-core mode-selective photonic lanterns (EC-MSPLs) with six modes, which can match well with EC-FMF in MIMO-free MDM systems. Simulation of the EC-MSPL using the beam propagation method was demonstrated employing a combination of either step-index or graded-index fibers with six different sizes of cores, and the taper transition length of 8 cm or 4 cm. Through numerical simulations and optimizations, both types of photonic lanterns can realize low loss transmission and low crosstalk of below -20.0  dB for all modes.

  8. Temperature modelling and prediction for activated sludge systems.

    PubMed

    Lippi, S; Rosso, D; Lubello, C; Canziani, R; Stenstrom, M K

    2009-01-01

    Temperature is an important factor affecting biomass activity, which is critical to maintain efficient biological wastewater treatment, and also physiochemical properties of mixed liquor as dissolved oxygen saturation and settling velocity. Controlling temperature is not normally possible for treatment systems but incorporating factors impacting temperature in the design process, such as aeration system, surface to volume ratio, and tank geometry can reduce the range of temperature extremes and improve the overall process performance. Determining how much these design or up-grade options affect the tank temperature requires a temperature model that can be used with existing design methodologies. This paper presents a new steady state temperature model developed by incorporating the best aspects of previously published models, introducing new functions for selected heat exchange paths and improving the method for predicting the effects of covering aeration tanks. Numerical improvements with embedded reference data provide simpler formulation, faster execution, easier sensitivity analyses, using an ordinary spreadsheet. The paper presents several cases to validate the model.

  9. Expression of monellin in a food-grade delivery system in Saccharomyces cerevisiae.

    PubMed

    Liu, Jun; Yan, Da-zhong; Zhao, Sheng-jun

    2015-10-01

    Genetically modified (GM) foods have caused much controversy. Construction of a food-grade delivery system is a desirable technique with presumptive impact on industrial applications from the perspective of bio-safety. The aim of this study was to construct a food-grade delivery system for Saccharomyces cerevisiae and to study the expression of monellin from the berries of the West African forest plant Dioscoreophyllum cumminsii in this system. A food-grade system for S. cerevisiae was constructed based on ribosomal DNA (rDNA)-mediated homologous recombination to enable high-copy-number integration of the expression cassette inserted into the rDNA locus. A copper resistance gene (CUP1) was used as the selection marker for yeast transformation. Because variants of transformants containing different copy numbers at the CUP1 locus can be readily selected after growth in the presence of elevated copper levels, we suggest that this system would prove useful in the generation of tandemly iterated gene clusters. Using this food-grade system, a single-chain monellin gene was heterologously expressed. The yield of monellin reached a maximum of 675 mg L(-1) . This system harbors exclusively S. cerevisiae DNA with no antibiotic resistance genes, and it should therefore be appropriate for safe use in the food industry. Monellin was shown to be expressed in this food-grade delivery system. To our knowledge, this is the first report so far on expression of monellin in a food-grade expression system in S. cerevisiae. © 2014 Society of Chemical Industry.

  10. Lessons from Enlightened Corporations.

    ERIC Educational Resources Information Center

    Blankstein, Alan M.

    1992-01-01

    The formula for improving U.S. schools can be found in the philosophy that helped transform Japanese industry and in Deming's 14 principles, emulated by many corporations. Deming's arguments against appraising individual performance through quotas or numerical goals call into question schools' current grading and merit pay practices. (12…

  11. Improved hairline crack detector and poor shell-quality eggs

    USDA-ARS?s Scientific Manuscript database

    Cracks frequently occur throughout various points of egg collection and processing and there are numerous high-speed online commercial crack detectors in use. The accuracy of crack detectors is validated by USDA human graders to ensure that they are in compliance with voluntary grade standards USDA...

  12. Working Together To Improve Middle School Student Achievement.

    ERIC Educational Resources Information Center

    Hatch, Holly; Hytten, Kathy

    1997-01-01

    Involving stakeholders in school-district assessment and planning provides a common learning experience that results in numerous organizational and professional growth benefits. This paper describes one district's experiences with a middle-grades reform audit, examining the rationale, procedures, and application of the audit and planning process…

  13. An introduction to UGRS: the ultimate grading and remanufacturing system

    Treesearch

    John Moody; Charles J. Gatchell; Elizabeth S. Walker; Powsiri Klinkhachorn

    1998-01-01

    The Ultimate Grading and Remanufactming System (UGRS) is an advanced computer program for grading and remanufacturing lumber. It is an interactive program that will both grade lumber according to NHLA rules and remanufacture it for maximum value. UGRS is written to run under Microsoft Windows 3.0 or later updates and provides a sophisticated graphical user interface....

  14. Graded activity for low back pain in occupational health care: a randomized, controlled trial.

    PubMed

    Staal, J Bart; Hlobil, Hynek; Twisk, Jos W R; Smid, Tjabe; Köke, Albère J A; van Mechelen, Willem

    2004-01-20

    Low back pain is a common medical and social problem frequently associated with disability and absence from work. However, data on effective return to work after interventions for low back pain are scarce. To determine the effectiveness of a behavior-oriented graded activity program compared with usual care. Randomized, controlled trial. Occupational health services department of an airline company in the Netherlands. 134 workers who were absent from work because of low back pain were randomly assigned to either graded activity (n = 67) or usual care (n = 67). Graded activity, a physical exercise program based on operant-conditioning behavioral principles, to stimulate a rapid return to work. Outcomes were the number of days of absence from work because of low back pain, functional status (Roland Disability Questionnaire), and severity of pain (11-point numerical scale). The median number of days of absence from work over 6 months of follow-up was 58 days in the graded activity group and 87 days in the usual care group. From randomization onward, graded activity was effective after 50 days of absence from work (hazard ratio, 1.9 [95% CI, 1.2 to 3.2]; P = 0.009). The graded activity group was more effective in improving functional status and pain than the usual care group. The effects, however, were small and not statistically significant. Graded activity was more effective than usual care in reducing the number of days of absence from work because of low back pain.

  15. Validation of International Society of Urological Pathology (ISUP) grading for prostatic adenocarcinoma in thin core biopsies using TROG 03.04 'RADAR' trial clinical data.

    PubMed

    Delahunt, B; Egevad, L; Srigley, J R; Steigler, A; Murray, J D; Atkinson, C; Matthews, J; Duchesne, G; Spry, N A; Christie, D; Joseph, D; Attia, J; Denham, J W

    2015-10-01

    In 2014 a consensus conference convened by the International Society of Urological Pathology (ISUP) adopted amendments to the criteria for Gleason grading and scoring (GS) for prostatic adenocarcinoma. The meeting defined a modified grading system based on 5 grading categories (grade 1, GS 3+3; grade 2, GS 3+4; grade 3, GS 4+3; grade 4, GS 8; grade 5, GS 9-10). In this study we have evaluated the prognostic significance of ISUP grading in 496 patients enrolled in the TROG 03.04 RADAR Trial. There were 19 grade 1, 118 grade 2, 193 grade 3, 88 grade 4 and 79 grade 5 tumours in the series, with follow-up for a minimum of 6.5 years. On follow-up 76 patients experienced distant progression of disease, 171 prostate specific antigen (PSA) progression and 39 prostate cancer deaths. In contrast to the 2005 modified Gleason system (MGS), the hazards of the distant and PSA progression endpoints, relative to grade 2, were significantly greater for grades 3, 4 and 5 of the 2014 ISUP grading scheme. Comparison of predictive ability utilising Harrell's concordance index, showed 2014 ISUP grading to significantly out-perform 2005 MGS grading for each of the three clinical endpoints.

  16. Validation of a classification system to grade fractionation in atrial fibrillation and correlation with automated detection systems.

    PubMed

    Hunter, Ross J; Diab, Ihab; Thomas, Glyn; Duncan, Edward; Abrams, Dominic; Dhinoja, Mehul; Sporton, Simon; Earley, Mark J; Schilling, Richard J

    2009-12-01

    We tested application of a grading system describing complex fractionated electrograms (CFE) in atrial fibrillation (AF) and used it to validate automated CFE detection (AUTO). Ten seconds bipolar electrograms were classified by visual inspection (VI) during ablation of persistent AF and the result compared with offline manual measurement (MM) by a second blinded operator: Grade 1 uninterrupted fractionated activity (defined as segments > or =70 ms) for > or =70% of recording and uninterrupted > or =1 s; Grade 2 interrupted fractionated activity > or =70% of recording; Grade 3 intermittent fractionated activity 30-70%; Grade 4 discrete (<70 ms) complex electrogram (> or =5 direction changes); Grade 5 discrete simple electrograms (< or =4 direction changes); Grade 6 scar. Grade by VI and MM for 100 electrograms agreed in 89%. Five hundred electrograms were graded on Carto and NavX by VI to validate AUTO in (i) detection of CFE (grades 1-4 considered CFE), and (ii) assessing degree of fractionation by correlating grade and score by AUTO (data shown as sensitivity, specificity, r): NavX 'CFE mean' 92%, 91%, 0.56; Carto 'interval confidence level' using factory settings 89%, 62%, -0.72, and other published settings 80%, 74%, -0.65; Carto 'shortest confidence interval' 74%, 70%, 0.43; Carto 'average confidence interval' 86%, 66%, 0.53. Grading CFE by VI is accurate and correlates with AUTO.

  17. Neuropathic pain: an updated grading system for research and clinical practice

    PubMed Central

    Finnerup, Nanna B.; Haroutounian, Simon; Kamerman, Peter; Baron, Ralf; Bennett, David L.H.; Bouhassira, Didier; Cruccu, Giorgio; Freeman, Roy; Hansson, Per; Nurmikko, Turo; Raja, Srinivasa N.; Rice, Andrew S.C.; Serra, Jordi; Smith, Blair H.; Treede, Rolf-Detlef; Jensen, Troels S.

    2016-01-01

    Abstract The redefinition of neuropathic pain as “pain arising as a direct consequence of a lesion or disease affecting the somatosensory system,” which was suggested by the International Association for the Study of Pain (IASP) Special Interest Group on Neuropathic Pain (NeuPSIG) in 2008, has been widely accepted. In contrast, the proposed grading system of possible, probable, and definite neuropathic pain from 2008 has been used to a lesser extent. Here, we report a citation analysis of the original NeuPSIG grading paper of 2008, followed by an analysis of its use by an expert panel and recommendations for an improved grading system. As of February, 2015, 608 eligible articles in Scopus cited the paper, 414 of which cited the neuropathic pain definition. Of 220 clinical studies citing the paper, 56 had used the grading system. The percentage using the grading system increased from 5% in 2009 to 30% in 2014. Obstacles to a wider use of the grading system were identified, including (1) questions about the relative significance of confirmatory tests, (2) the role of screening tools, and (3) uncertainties about what is considered a neuroanatomically plausible pain distribution. Here, we present a revised grading system with an adjusted order, better reflecting clinical practice, improvements in the specifications, and a word of caution that even the “definite” level of neuropathic pain does not always indicate causality. In addition, we add a table illustrating the area of pain and sensory abnormalities in common neuropathic pain conditions and propose areas for further research. PMID:27115670

  18. The effects of regeneration temperature of the desiccant wheel on the performance of desiccant cooling cycles for greenhouse thermally insulated

    NASA Astrophysics Data System (ADS)

    Rjibi, Amel; Kooli, Sami; Guizani, Amenaallah

    2018-05-01

    The use of solar energy for cooling greenhouses in the hot period in Mediterranean climate is an important issue. Desiccant evaporative cooling (DEC) system is advantageous because it uses a low grade thermal energy and preserves the merits to be friendly environmentally technology. In this paper, a numerical investigation was carried out on a desiccant cooling system powered by air solar collectors coupled to an insulated greenhouse. The influence of the regeneration temperature on the air stream properties at every system component state point was studied. The performance of the desiccant cooling system was evaluated in terms of thermal and electric coefficient of performance. Results show that the best performance of the system (COPel = 14 and COPth = 0.94) was obtained for a 60 °C regeneration temperature and a supply flow rate ratio of 0.2. An economic analysis shows that the use of the DEC system for greenhouse cooling is attractive and profitable since the payback period is 1 years. The use of the proposed system allows saving 9396 kWh/year of electric energy compared to conventional system.

  19. An analysis technique for testing log grades

    Treesearch

    Carl A. Newport; William G. O' Regan

    1963-01-01

    An analytical technique that may be used in evaluating log-grading systems is described. It also provides means of comparing two or more grading systems, or a proposed change with the system from which it was developed. The total volume and computed value of lumber from each sample log are the basic data used.

  20. Outcome prediction of third ventriculostomy: a proposed hydrocephalus grading system.

    PubMed

    Kehler, U; Regelsberger, J; Gliemroth, J; Westphal, M

    2006-08-01

    An important factor in making a recommendation for different treatment modalities in hydrocephalus patients (VP shunt versus endoscopic third ventriculostomy) is the definition of the underlying pathology which determines the prognosis/outcome of the surgical procedure. Third ventriculostomies (3rd VS) are successful mainly in obstructive hydrocephalus but also in some subtypes of communicating hydrocephalus. A simple, easily applicable grading system that is designed to predict the outcome of 3rd VS is proposed. The hydrocephalus is graded on the basis of the extent of downward bulging of the floor of the third ventricle, which reflects the pressure gradient between the 3rd ventricle and the basal cisterns, presence of directly visualised CSF pathway obstruction in MRI, and the progression of the clinical symptoms resulting in five different grades. In this proposed grading system, grade 1 hydrocephalus subtype shows no downward bulged floor of the 3rd ventricle, no obstruction of the CSF pathway, and no progressive symptoms of hydrocephalus. There is no indication for 3rd VS. Grades 2 to 4 show different combinations of the described parameters. Grade 5 subtype shows a markedly downward bulged floor of the 3rd ventricle and direct detection of the CSF pathway obstruction (i.e., aqueductal stenosis) with progressive clinical deterioration. Retrospective application of this grading scheme to a series of 72 3rd VS has demonstrated a high correlation with the outcome: The success rate in grade 3 reached 40%, in grade 4: 58%, and in grade 5: 95%. This standardised grading system predicts the outcome of 3rd VS and helps in decision making for 3rd VS versus VP shunting.

  1. A comparative study using WHO and binary oral epithelial dysplasia grading systems in actinic cheilitis.

    PubMed

    Câmara, P R; Dutra, S N; Takahama Júnior, A; Fontes, Kbfc; Azevedo, R S

    2016-09-01

    To evaluate comparatively the influence of histopathological features on epithelial dysplasia (ED) and the effectiveness in usage of WHO and binary grading systems in actinic cheilitis (AC). Cytological and architectural alterations established by WHO for ED were evaluated in 107 cases of AC. Epithelial dysplasia was graded using WHO and binary systems. The comparisons were performed using kappa, chi-square, and phi coefficient tests (P < 0.05). Most cases were classified as mild ED (44.5%) in the WHO system and as low risk for malignant transformation (64.5%) in the binary system. There was a positive correlation between WHO and binary systems (k = 0.33; P < 0.0002). Loss of basal cell polarity (P < 0.001) was associated with severity of ED grade in the WHO system. Anisonucleosis (P < 0.0001), nuclear pleomorphism (P < 0.0001), anisocytosis (P = 0.03), cell pleomorphism (P = 0.002) increased nuclear/cytoplasm ratio (P < 0.0001), increased nuclear size (P < 0.0001), increased number of mitotic figures (P = 0.0006), and dyskeratosis (P = 0.008) were associated with severity of ED grade in the binary system. It seems that usage of binary ED grading system in AC may be more precise because there is correlation between many of cytological and some of architectural microscopic alterations with increased grade of ED. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  2. Compact flexible multifrequency splitter based on plasmonic graded metallic grating arc waveguide.

    PubMed

    Han, Chao; Wang, Zhaohong; Chu, Yangyang; Zhao, Xiaodan; Zhang, Xuanru

    2018-04-15

    A compact flexible multifrequency splitter based on an arc waveguide constructed of plasmonic metallic grating structures with graded-height T-grooves is proposed and studied. The dispersion curves and cutoff frequencies of the plasmonic grating waveguides with different T-groove metallic grating heights are different. The guided spoof surface plasmonic polariton waves at different frequencies can be localized at dissimilar angles along the graded grating arc waveguide. The output flexibility at an arbitrary groove for different frequencies is realized by introducing an additional symmetrical T-groove structure as an output. The compact four-, seven-, and eight-output frequency splitters demonstrate its flexible multifrequency separation capability at different output angle locations, while the dimensional size of the frequency splitters is not increased. Measurement results at the microwave frequency display excellent agreement with numerical simulation results.

  3. Clicking for Grades? Really? Investigating the Use of Clickers for Awarding Grade-Points in Post-Secondary Education

    ERIC Educational Resources Information Center

    White, Peter; Syncox, David; Alters, Brian

    2011-01-01

    Using classroom response systems (clickers) to accumulate grade-points has become a controversial practice as response systems have become more widely used in the last decade. Although some instructors opt to use clickers on a non-grades basis, it has become quite common to reward students for (a) correct answers, (b) participating in clicker…

  4. Marketing low-grade hardwoods for furniture stock - a new approach

    Treesearch

    Hugh W. Reynolds; Charles J. Gatchell

    1979-01-01

    A hardwood shortage of high-grade lumber exists while there is a surplus of low-grade hardwood timber. Two things are needed for the surplus to correct the shortage: a new manufacturing system and a new marketing technique. Utilization research at the Princeton Forestry Sciences Laboratory has developed the new system for converting low-grade hardwood for furniture use...

  5. ALBI versus Child-Pugh grading systems for liver function in patients with hepatocellular carcinoma.

    PubMed

    Na, Seong K; Yim, Sun Y; Suh, Sang J; Jung, Young K; Kim, Ji H; Seo, Yeon S; Yim, Hyung J; Yeon, Jong E; Byun, Kwan S; Um, Soon H

    2018-04-01

    The prognostic performance of the albumin-bilirubin (ALBI) grade in hepatocellular carcinoma (HCC) as an objective method of assessing liver function was investigated. Data from 2099 patients with HCC in Korea were collected and analyzed retrospectively. The discriminative performance of ALBI grade was compared with Child-Pugh (C-P) grade for different stages or treatments. The median follow up duration was 16.2 months (range: 1.0-124.9). The median survival times were 49.7 months for C-P grade A (65.8%), 12.4 months for C-P grade B (25.5%), and 4.2 months for C-P grade C (8.6%) (P < 0.001). The median survival times were 84.2 months for ALBI grade 1 (32.8%), 25.5 months for ALBI grade 2 (53.5%), and 7.7 months for ALBI grade 3 (13.7%) (P < 0.001). In early UICC stages, ALBI grade showed better discriminative performance than C-P grade. In curative treatments, ALBI grade also showed better discriminative performance than C-P grade (Harrell's C: 0.624 (C-P grade) vs 0.667 [ALBI grade]). ALBI grade provided better prognostic performance in survival analysis and better distribution of the grades than C-P grade in HCC, suggesting that ALBI grade could be a good alternative grading system for liver function in patients with HCC. © 2018 Wiley Periodicals, Inc.

  6. Numerical scoring for the Classic BILAG index.

    PubMed

    Cresswell, Lynne; Yee, Chee-Seng; Farewell, Vernon; Rahman, Anisur; Teh, Lee-Suan; Griffiths, Bridget; Bruce, Ian N; Ahmad, Yasmeen; Prabu, Athiveeraramapandian; Akil, Mohammed; McHugh, Neil; Toescu, Veronica; D'Cruz, David; Khamashta, Munther A; Maddison, Peter; Isenberg, David A; Gordon, Caroline

    2009-12-01

    To develop an additive numerical scoring scheme for the Classic BILAG index. SLE patients were recruited into this multi-centre cross-sectional study. At every assessment, data were collected on disease activity and therapy. Logistic regression was used to model an increase in therapy, as an indicator of active disease, by the Classic BILAG score in eight systems. As both indicate inactivity, scores of D and E were set to 0 and used as the baseline in the fitted model. The coefficients from the fitted model were used to determine the numerical values for Grades A, B and C. Different scoring schemes were then compared using receiver operating characteristic (ROC) curves. Validation analysis was performed using assessments from a single centre. There were 1510 assessments from 369 SLE patients. The currently used coding scheme (A = 9, B = 3, C = 1 and D/E = 0) did not fit the data well. The regression model suggested three possible numerical scoring schemes: (i) A = 11, B = 6, C = 1 and D/E = 0; (ii) A = 12, B = 6, C = 1 and D/E = 0; and (iii) A = 11, B = 7, C = 1 and D/E = 0. These schemes produced comparable ROC curves. Based on this, A = 12, B = 6, C = 1 and D/E = 0 seemed a reasonable and practical choice. The validation analysis suggested that although the A = 12, B = 6, C = 1 and D/E = 0 coding is still reasonable, a scheme with slightly less weighting for B, such as A = 12, B = 5, C = 1 and D/E = 0, may be more appropriate. A reasonable additive numerical scoring scheme based on treatment decision for the Classic BILAG index is A = 12, B = 5, C = 1, D = 0 and E = 0.

  7. Numerical scoring for the Classic BILAG index

    PubMed Central

    Cresswell, Lynne; Yee, Chee-Seng; Farewell, Vernon; Rahman, Anisur; Teh, Lee-Suan; Griffiths, Bridget; Bruce, Ian N.; Ahmad, Yasmeen; Prabu, Athiveeraramapandian; Akil, Mohammed; McHugh, Neil; Toescu, Veronica; D’Cruz, David; Khamashta, Munther A.; Maddison, Peter; Isenberg, David A.

    2009-01-01

    Objective. To develop an additive numerical scoring scheme for the Classic BILAG index. Methods. SLE patients were recruited into this multi-centre cross-sectional study. At every assessment, data were collected on disease activity and therapy. Logistic regression was used to model an increase in therapy, as an indicator of active disease, by the Classic BILAG score in eight systems. As both indicate inactivity, scores of D and E were set to 0 and used as the baseline in the fitted model. The coefficients from the fitted model were used to determine the numerical values for Grades A, B and C. Different scoring schemes were then compared using receiver operating characteristic (ROC) curves. Validation analysis was performed using assessments from a single centre. Results. There were 1510 assessments from 369 SLE patients. The currently used coding scheme (A = 9, B = 3, C = 1 and D/E = 0) did not fit the data well. The regression model suggested three possible numerical scoring schemes: (i) A = 11, B = 6, C = 1 and D/E = 0; (ii) A = 12, B = 6, C = 1 and D/E = 0; and (iii) A = 11, B = 7, C = 1 and D/E = 0. These schemes produced comparable ROC curves. Based on this, A = 12, B = 6, C = 1 and D/E = 0 seemed a reasonable and practical choice. The validation analysis suggested that although the A = 12, B = 6, C = 1 and D/E = 0 coding is still reasonable, a scheme with slightly less weighting for B, such as A = 12, B = 5, C = 1 and D/E = 0, may be more appropriate. Conclusions. A reasonable additive numerical scoring scheme based on treatment decision for the Classic BILAG index is A = 12, B = 5, C = 1, D = 0 and E = 0. PMID:19779027

  8. Ready or Not: The Academic College Readiness of Southeast Asian Americans

    ERIC Educational Resources Information Center

    Her, Chia S.

    2014-01-01

    The educational experiences of Southeast Asian Americans, particularly Cambodian Americans, Hmong Americans, Laotian Americans, and Vietnamese Americans, are characterized by numerous challenges, which can be attributed to their migration history, socioeconomic status, and English proficiency. By the end of 11th grade, a high percentage of…

  9. Candidate Success and edTPA: Looking at the Data

    ERIC Educational Resources Information Center

    Evans, Lesley A.; Kelly, Mary K.; Baldwin, Joni L.; Arnold, Jackie M.

    2016-01-01

    This descriptive study looks at the correlations between Teacher Performance Assessment (edTPA) data and numerous program data points, including GPA, major GPA, and benchmark assignment scores, gathered in an Early Childhood Education (ECE) program. Previous studies have looked to correlate grade point average (GPA) with pre-service teacher…

  10. Facilitative Effects of Practice upon Nonverbal Creativity.

    ERIC Educational Resources Information Center

    Roweton, William E.; Spencer, Herbert L., Jr.

    Numerous studies of verbal creativity indicate that idea originality increases progressively as more ideas are produced. The present study tested the effects of practice upon nonverbal creativity. Thirty-two fifth grade children were administered Form A and/or Form B of Torrance's picture completion task for 5 consecutive days. Figural originality…

  11. Developmental Associations between Adolescent Alcohol Use and Dating Aggression

    ERIC Educational Resources Information Center

    Reyes, Heathe Luz McNaughton; Foshee, Vangie A.; Bauer, Daniel J.; Ennett, Susan T.

    2012-01-01

    Although numerous studies have established a link between alcohol use and partner violence in adulthood, little research has examined this relation during adolescence. The current study used multivariate growth models to examine relations between alcohol use and dating aggression across Grades 8 through 12, controlling for shared risk factors…

  12. Effectiveness of a Lab Manual Delivered on CD-ROM

    ERIC Educational Resources Information Center

    Brickman, Peggy; Ketter, Catherine A. Teare; Pereira, Monica

    2005-01-01

    Although electronic instructional media are becoming increasingly prevalent in science classrooms, their worth remains unproven. Here, student perceptions and performance using CD-ROM delivery of lab materials are assessed. Numerous learning barriers that produced lower lab grades for students using a CD-ROM lab manual in comparison to a print…

  13. Juneau Indian Studies Elementary Curriculum Guide. Grades K-5.

    ERIC Educational Resources Information Center

    Cadiente, Ronalda

    Designed to provide instruction in Tlingit culture as an integral part of the K-5 social studies curriculum, this guide presents teachers with extensive lesson plans and numerous resource materials. The units of study focus on the culture and environment of southeast Alaska and emphasize experiential learning activities. Each grade…

  14. Middle School Educators' Perceptions of Online Professional Development

    ERIC Educational Resources Information Center

    Theodocion, Kelley E.

    2012-01-01

    Numerous researchers have investigated distance education in postsecondary settings, but there is a paucity of research regarding the design and delivery of online professional development for K-12 educators. The goal of this mixed methods sequential exploratory study was to examine attitudes of middle grades educators toward an online…

  15. Storytelling and the Emergent Reader.

    ERIC Educational Resources Information Center

    Malo, Eve; Bullard, Julie

    Numerous studies have linked reading aloud to preschoolers and these children's later success as readers. But some of the parents with whom teachers work, whether they work at Head Start, childcare centers, or primary grades, have limited reading skills. However, the Hispanic, Native American, African American, Irish American, and many other…

  16. Environmental Pollution, Student's Book (Experiences/Experiments/Activities).

    ERIC Educational Resources Information Center

    Weaver, Elbert C.

    Described in this student's manual are numerous experiments to acquaint the learner with community environmental problems. Experiments are relatively simple and useful in the junior high school grades. Activities are provided which emphasize some of the materials involved in pollution problems, such as carbon dioxide, sulfur compounds, and others,…

  17. Complexities of Counting.

    ERIC Educational Resources Information Center

    Stake, Bernadine Evans

    This document focuses on one child's skip counting methods. The pupil, a second grade student at Steuben School, in Kankakee, Illinois, was interviewed as she made several attempts at counting twenty-five poker chips on a circular piece of paper. The interview was part of a larger study of "Children's Conceptions of Number and Numeral,"…

  18. An Investigation of the Mathematics-Vocabulary Knowledge of First-Grade Students

    ERIC Educational Resources Information Center

    Powell, Sarah R.; Nelson, Gena

    2017-01-01

    Competency with mathematics requires use of numerals and symbols as well as an understanding and use of mathematics vocabulary (e.g., "add," "more," "triangle"). Currently, no measures exist in which the primary function is to gauge mathematics-vocabulary understanding. We created a 64-item mathematics-vocabulary…

  19. The Uneven Implementation of Universal School Policies: Maternal Education and Florida's Mandatory Grade Retention Policy

    ERIC Educational Resources Information Center

    LiCalsi, Christina; Ozek, Umut; Figlio, David

    2016-01-01

    Research consistently demonstrates a strong, positive relationship between parents' socioeconomic status and children's educational achievement. This achievement gap is already present when children enter school in kindergarten and, despite the numerous policies aimed at leveling the educational playing field for disadvantaged students, it does…

  20. Acute appendicitis: proposal of a new comprehensive grading system based on clinical, imaging and laparoscopic findings.

    PubMed

    Gomes, Carlos Augusto; Sartelli, Massimo; Di Saverio, Salomone; Ansaloni, Luca; Catena, Fausto; Coccolini, Federico; Inaba, Kenji; Demetriades, Demetrios; Gomes, Felipe Couto; Gomes, Camila Couto

    2015-01-01

    Advances in the technology and improved access to imaging modalities such as Computed Tomography and laparoscopy have changed the contemporary diagnostic and management of acute appendicitis. Complicated appendicitis (phlegmon, abscess and/ or diffuse peritonitis), is now reliably distinguished from uncomplicated cases. Therefore, a new comprehensive grading system for acute appendicitis is necessary. The goal is review and update the laparoscopic grading system of acute appendicitis and to provide a new standardized classification system to allow more uniform patient stratification. During the last World Society of Emergency Surgery Congress in Israel (July, 2015), a panel involving Acute Appendicitis Experts and the author's discussed many current aspects about the acute appendicitis between then, it will be submitted a new comprehensive disease grading system. It was idealized based on three aspect of the disease (clinical and imaging presentation and laparoscopic findings). The new grading system may provide a standardized system to allow more uniform patient stratification for appendicitis research. In addition, may aid in determining optimal management according to grade. Lastly, what we want is to draw a multicenter observational study within the World Society of Emergency Surgery (WSES) based on this design.

  1. An analytical/numerical correlation study of the multiple concentric cylinder model for the thermoplastic response of metal matrix composites

    NASA Technical Reports Server (NTRS)

    Pindera, Marek-Jerzy; Salzar, Robert S.; Williams, Todd O.

    1993-01-01

    The utility of a recently developed analytical micromechanics model for the response of metal matrix composites under thermal loading is illustrated by comparison with the results generated using the finite-element approach. The model is based on the concentric cylinder assemblage consisting of an arbitrary number of elastic or elastoplastic sublayers with isotropic or orthotropic, temperature-dependent properties. The elastoplastic boundary-value problem of an arbitrarily layered concentric cylinder is solved using the local/global stiffness matrix formulation (originally developed for elastic layered media) and Mendelson's iterative technique of successive elastic solutions. These features of the model facilitate efficient investigation of the effects of various microstructural details, such as functionally graded architectures of interfacial layers, on the evolution of residual stresses during cool down. The available closed-form expressions for the field variables can readily be incorporated into an optimization algorithm in order to efficiently identify optimal configurations of graded interfaces for given applications. Comparison of residual stress distributions after cool down generated using finite-element analysis and the present micromechanics model for four composite systems with substantially different temperature-dependent elastic, plastic, and thermal properties illustrates the efficacy of the developed analytical scheme.

  2. Vibration analysis of a rotating functionally graded tapered microbeam based on the modified couple stress theory by DQEM

    NASA Astrophysics Data System (ADS)

    Ghadiri, Majid; Shafiei, Navvab; Alireza Mousavi, S.

    2016-09-01

    Due to having difficulty in solving governing nonlinear differential equations of a non-uniform microbeam, a few numbers of authors have studied such fields. In the present study, for the first time, the size-dependent vibration behavior of a rotating functionally graded (FG) tapered microbeam based on the modified couple stress theory is investigated using differential quadrature element method (DQEM). It is assumed that physical and mechanical properties of the FG microbeam are varying along the thickness that will be defined as a power law equation. The governing equations are determined using Hamilton's principle, and DQEM is presented to obtain the results for cantilever and propped cantilever boundary conditions. The accuracy and validity of the results are shown in several numerical examples. In order to display the influence of size on the first two natural frequencies and consequently changing of some important microbeam parameters such as material length scale, rate of cross section, angular velocity and gradient index of the FG material, several diagrams and tables are represented. The results of this article can be used in designing and optimizing elastic and rotary-type micro-electro-mechanical systems like micro-motors and micro-robots including rotating parts.

  3. Source of a micro-nutrient in a semi-synthetic basal diet as a causative factor in inducing urinary calculi in rats and its inhibition by PSC 833, a potent inhibitor of P-glycoprotein.

    PubMed

    Kankesan, Janarthanan; Vanama, Ramesh; Renlund, Richard; Thiessen, Jake J; Ling, Victor; Rao, Prema M; Rajalakshmi, Srinivasan; Sarma, Dittakavi S R

    2003-08-01

    We report a serendipitous finding of urinary calculi in rats fed a semi-synthetic basal diet. This observation was made during ongoing studies to evaluate the inhibitory effect of PSC 833, a potent inhibitor of P-glycoprotein, on development of tumors in rodent tumor model systems. A large number of specific-pathogen-free (SPF) female Sprague-Dawley and SPF male Fischer 344 rats being fed the diet were euthanized when it became evident clinically that they were uremic. At necropsy, the renal pelvis, ureters, and urinary bladder contained numerous calculi. The presence of urinary calculi was determined to be related to the source of a Food Chemical Codex grade of choline bitartrate. Rats being fed the same basal diet containing the United States Pharmacopia grade of choline bitartrate failed to develop urinary calculi. Interestingly, rats treated with the P-glycoprotein inhibitor were at significantly reduced risk of developing urinary calculi. This finding highlights how something seemingly innocuous as a minor dietary constituent can have a profound impact and, thereby, affect experimental outcome.

  4. Comparative evaluation of H&H and WFNS grading scales with modified H&H (sans systemic disease): A study on 1000 patients with subarachnoid hemorrhage.

    PubMed

    Aggarwal, Ashish; Dhandapani, Sivashanmugam; Praneeth, Kokkula; Sodhi, Harsimrat Bir Singh; Pal, Sudhir Singh; Gaudihalli, Sachin; Khandelwal, N; Mukherjee, Kanchan K; Tewari, M K; Gupta, Sunil Kumar; Mathuriya, S N

    2018-01-01

    The comparative studies on grading in subarachnoid hemorrhage (SAH) had several limitations such as the unclear grading of Glasgow Coma Scale 15 with neurological deficits in World Federation of Neurosurgical Societies (WFNS), and the inclusion of systemic disease in Hunt and Hess (H&H) scales. Their differential incremental impacts and optimum cut-off values for unfavourable outcome are unsettled. This is a prospective comparison of prognostic impacts of grading schemes to address these issues. SAH patients were assessed using WFNS, H&H (including systemic disease), modified H&H (sans systemic disease) and followed up with Glasgow Outcome Score (GOS) at 3 months. Their performance characteristics were analysed as incremental ordinal variables and different grading scale dichotomies using rank-order correlation, sensitivity, specificity, positive predictive value, negative predictive value, Youden's J and multivariate analyses. A total of 1016 patients were studied. As univariate incremental variable, H&H sans systemic disease had the best negative rank-order correlation coefficient (-0.453) with respect to lower GOS (p < 0.001). As univariate dichotomized category, WFNS grades 3-5 had the best performance index of 0.39 to suggest unfavourable GOS with a specificity of 89% and sensitivity of 51%. In multivariate incremental analysis, H&H sans systemic disease had the greatest adjusted incremental impact of 0.72 (95% confidence interval (CI) 0.54-0.91) against a lower GOS as compared to 0.6 (95% CI 0.45-0.74) and 0.55 (95% CI 0.42-0.68) for H&H and WFNS grades, respectively. In multivariate categorical analysis, H&H grades 4-5 sans systemic disease had the greatest impact on unfavourable GOS with an adjusted odds ratio of 6.06 (95% CI 3.94-9.32). To conclude, H&H grading sans systemic disease had the greatest impact on unfavourable GOS. Though systemic disease is an important prognostic factor, it should be considered distinctly from grading. Appropriate cut-off values suggesting unfavourable outcome for H&H and WFNS were 4-5 and 3-5, respectively, indicating the importance of neurological deficits in addition to level of consciousness.

  5. Prognostic Value of the New Prostate Cancer International Society of Urological Pathology Grade Groups.

    PubMed

    Offermann, Anne; Hohensteiner, Silke; Kuempers, Christiane; Ribbat-Idel, Julika; Schneider, Felix; Becker, Finn; Hupe, Marie Christine; Duensing, Stefan; Merseburger, Axel S; Kirfel, Jutta; Reischl, Markus; Lubczyk, Verena; Kuefer, Rainer; Perner, Sven

    2017-01-01

    Gleason grading is the best independent predictor for prostate cancer (PCa) progression. Recently, a new PCa grading system has been introduced by the International Society of Urological Pathology (ISUP) and is recommended by the World Health Organization (WHO). Following studies observed more accurate and simplified grade stratification of the new system. Aim of this study was to compare the prognostic value of the new grade groups compared to the former Gleason Grading and to determine whether re-definition of Gleason Pattern 4 might reduce upgrading from prostate biopsy to radical prostatectomy (RP) specimen. A cohort of men undergoing RP from 2002 to 2015 at the Hospital of Goeppingen (Goeppingen, Germany) was used for this study. In total, 339 pre-operative prostatic biopsies and corresponding RP specimens, as well as additional 203 RP specimens were re-reviewed for Grade Groups according to the ISUP. Biochemical recurrence-free survival (BFS) after surgery was used as endpoint to analyze prognostic significance. Other clinicopathological data included TNM-stage and pre-operative PSA level. Kaplan-Meier analysis revealed risk stratification of patients based on both former Gleason Grading and ISUP Grade Groups, and was statistically significant using the log-rank test ( p  < 0.001). Both grading systems significantly correlated with TNM-stage and pre-operative PSA level ( p  < 0.001). Higher tumor grade in RP specimen compared to corresponding pre-operative biopsy was observed in 44 and 34.5% of cases considering former Gleason Grading and ISUP Grade Groups, respectively. Both, former Gleason Grading and ISUP Grade Groups predict survival when applied on tumors in prostatic biopsies as well as RP specimens. This is the first validation study on a large representative German community-based cohort to compare the former Gleason Grading with the recently introduced ISUP Grade Groups. Our data indicate that the ISUP Grade Groups do not improve predictive value of PCa grading and might be less sensitive in deciphering tumors with 3 + 4 and 4 + 3 pattern on RP specimen. However, the Grade Group system results less frequently in an upgrading from biopsy to the corresponding RP specimens, indicating a lower risk to miss potentially aggressive tumors not represented on biopsies.

  6. Increased anatomic severity in appendicitis is associated with outcomes in a South African population.

    PubMed

    Hernandez, Matthew C; Kong, Victor Y; Aho, Johnathon M; Bruce, John L; Polites, Stephanie F; Laing, Grant L; Zielinski, Martin D; Clarke, Damian L

    2017-07-01

    Severity of emergency general surgery (EGS) diseases has not been standardized until recently. The American Association for the Surgery of Trauma (AAST) proposed an anatomic severity grading system for EGS diseases to facilitate communication and quality comparisons between providers and hospitals. Previous work has demonstrated validity of the system for appendicitis in the United States. To demonstrate generalizability, we aim to externally validate this grading system in South African patients with appendicitis. Patients with acute appendicitis during 2010 to 2016 were identified at multi-institutional sites within South Africa. Baseline demographics and procedure types were recorded, and AAST grades were assigned based on intraoperative findings. Outcomes included duration of stay, mortality, and Clavien-Dindo complications. Summary statistical univariate and nominal logistic regression analyses were performed to compare AAST grade and outcomes. A total of 1,415 patients with a median (interquartile range) age of 19 years (14-28 years) were included (55% men). One hundred percent underwent appendectomy: 63.5% completed via midline laparotomy, 36.5% via limited incision (31.8% via McBurney incision and 4.7% via laparoscopy). Overall, 30-day mortality rate was 1.4% with an overall complication rate of 44%. Most common complications included surgical site infection (n = 147, 10.4%), pneumonia (n = 105, 7.4%), and renal failure (n = 64, 4.5%). Distribution of AAST grade is as follows: Grade 0 (10, 0.7%), Grade 1 (247, 17.4%), Grade 2 (280, 19.8%), Grade 3 (158, 11.3%), Grade 4 (179, 12.6%), and Grade 5 (541, 38.2%). Increased median (interquartile range) AAST grades were recorded in patients with complications, 5 (3-5) compared with those without (2 [1-3], p = 0.001). Duration of stay was increased for patients with higher AAST grades: 4 and 5 (10.6 ± 5.9 days) versus I and II (3.6 ± 4.3 days; p = 0.001). Area under the receiver operating characteristic analysis to predict presence of any complication based on AAST grade was 0.90. The AAST EGS grading system is valid to predict important clinical outcomes in a South African population with an increased degree of severity on presentation. These results support generalizability of the AAST EGS grading system for appendicitis in a developing nation. Prognostic, level II.

  7. C2 nerve root on magnetic resonance imaging of occipital neuralgia.

    PubMed

    Yi, Minkyung; Lee, Joon Woo; Yeom, Jin S; Joe, Eugene; Hong, Sung Hwan; Lee, Guen Young; Kang, Heung Sik

    2014-06-01

    Review and grade the morphology of the C1-C2 neural foramina, from the MR images of patients who underwent C1-C2 spinal surgery, and determine the relationship with ON. To evaluate the feasibility of MRI for C1-C2 neural foramen evaluation with a new grading system and to correlate the C1-C2 neural foramen grade with ON. There have been no MRI studies of patients with and without ON in relation to C2 nerve root ganglion findings. Among the registry of 124 patients who underwent C1-C2 spinal surgery between July 2004 and May 2012 in Seoul National University Bundang Hospital, we enrolled 101 patients who had information about ON and a relevant preoperative cervical spine MR image. A total of 202 neural foramina were evaluated with our new C1-C2 neural foramen grading system (grade, 0-3) using consensus reading by 2 experienced radiologists who were blinded to the clinical information. The relationship between the C1-C2 grading system and ON was assessed using a χ test and Fisher exact test. Inter- and intraobserver reliability agreement was assessed using the κ statistic. All C1-C2 neural foramina were delineated on T2 parasagittal images. Among 202 C1-C2 neural foramina, grade zero was found in 49 foramina (24.3%), grade 1 in 95 (47.0%), grade 2 in 30 (14.9%), and grade 3 in 28 (13.9%). Grade 1 stenosis was most frequently noted. The grade 2 group had the most frequent prevalence of ON (43.3%), followed by grade 3 (35.7%), grade zero (30.6%), and grade 1 (29.5%). However, the relationship between the grade and ON was not statistically significant. Inter- and intraobserver agreements were substantially high. C1-C2 neural foramina can be depicted on MR image. However, the relationship between the new grading system for C1-C2 neural foramina and ON was not statistically significant. 4.

  8. The Impact of Framing Effect on Student Preferences for University Grading Systems

    ERIC Educational Resources Information Center

    Smith, Jeffrey K.; Smith, Lisa F.

    2009-01-01

    Kahneman and Tversky's (1979, 2000; Tversky & Kahneman, 1981) work in decision-making was applied to student preferences for grading practices. Undergraduate psychology students (n = 240) were randomly assigned to 1 of 3 framing conditions related to how a university course might be graded: a 100 point system, a percentage system, and an open…

  9. Towards Adaptive Educational Assessments: Predicting Student Performance using Temporal Stability and Data Analytics in Learning Management Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Thakur, Gautam; Olama, Mohammed M; McNair, Wade

    Data-driven assessments and adaptive feedback are becoming a cornerstone research in educational data analytics and involve developing methods for exploring the unique types of data that come from the educational context. For example, predicting college student performance is crucial for both the students and educational institutions. It can support timely intervention to prevent students from failing a course, increasing efficacy of advising functions, and improving course completion rate. In this paper, we present our efforts in using data analytics that enable educationists to design novel data-driven assessment and feedback mechanisms. In order to achieve this objective, we investigate temporal stabilitymore » of students grades and perform predictive analytics on academic data collected from 2009 through 2013 in one of the most commonly used learning management systems, called Moodle. First, we have identified the data features useful for assessments and predicting student outcomes such as students scores in homework assignments, quizzes, exams, in addition to their activities in discussion forums and their total Grade Point Average(GPA) at the same term they enrolled in the course. Second, time series models in both frequency and time domains are applied to characterize the progression as well as overall projections of the grades. In particular, the model analyzed the stability as well as fluctuation of grades among students during the collegiate years (from freshman to senior) and disciplines. Third, Logistic Regression and Neural Network predictive models are used to identify students as early as possible who are in danger of failing the course they are currently enrolled in. These models compute the likelihood of any given student failing (or passing) the current course. The time series analysis indicates that assessments and continuous feedback are critical for freshman and sophomores (even with easy courses) than for seniors, and those assessments may be provided using the predictive models. Numerical results are presented to evaluate and compare the performance of the developed models and their predictive accuracy. Our results show that there are strong ties associated with the first few weeks for coursework and they have an impact on the design and distribution of individual modules.« less

  10. A new MRI grading system for chondromalacia patellae.

    PubMed

    Özgen, Ali; Taşdelen, Neslihan; Fırat, Zeynep

    2017-04-01

    Background Chondromalacia patellae is a very common disorder. Although magnetic resonance imaging (MRI) is widely used to investigate patellar cartilage lesions, there is no descriptive MRI-based grading system for chondromalacia patellae. Purpose To propose a new MRI grading system for chondromalacia patellae with corresponding high resolution images which might be useful in precisely reporting and comparing knee examinations in routine daily practice and used in predicting natural course and clinical outcome of the patellar cartilage lesions. Material and Methods High resolution fat-saturated proton density (FS PD) images in the axial plane with corresponding T2 mapping images were reviewed. A detailed MRI grading system covering the deficiencies of the existing gradings has been set and presented on these images. Two experienced observers blinded to clinical data examined 44 knee MR images and evaluated patellar cartilage changes according to the proposed grading system. Inter- and intra-rater validity testing using kappa statistics were calculated. Results A descriptive and detailed grading system with corresponding FS PD and T2 mapping images has been presented. Inter-rater agreement was 0.80 (95% confidence interval [CI], 0.71-0.89). Intra-rater agreements were 0.83 (95% CI, 0.74-0.91) for observer A and 0.79 (95% CI, 0.70-0.88) for observer B (k-values). Conclusion We present a new MRI grading system for chondromalacia patellae with corresponding images and good inter- and intra-rater agreement which might be useful in reporting and comparing knee MRI examinations in daily practice and may also have the potential for using more precisely predicting prognosis and clinical outcome of the patients.

  11. Systems for grading the quality of evidence and the strength of recommendations I: Critical appraisal of existing approaches The GRADE Working Group

    PubMed Central

    Atkins, David; Eccles, Martin; Flottorp, Signe; Guyatt, Gordon H; Henry, David; Hill, Suzanne; Liberati, Alessandro; O'Connell, Dianne; Oxman, Andrew D; Phillips, Bob; Schünemann, Holger; Edejer, Tessa Tan-Torres; Vist, Gunn E; Williams, John W

    2004-01-01

    Background A number of approaches have been used to grade levels of evidence and the strength of recommendations. The use of many different approaches detracts from one of the main reasons for having explicit approaches: to concisely characterise and communicate this information so that it can easily be understood and thereby help people make well-informed decisions. Our objective was to critically appraise six prominent systems for grading levels of evidence and the strength of recommendations as a basis for agreeing on characteristics of a common, sensible approach to grading levels of evidence and the strength of recommendations. Methods Six prominent systems for grading levels of evidence and strength of recommendations were selected and someone familiar with each system prepared a description of each of these. Twelve assessors independently evaluated each system based on twelve criteria to assess the sensibility of the different approaches. Systems used by 51 organisations were compared with these six approaches. Results There was poor agreement about the sensibility of the six systems. Only one of the systems was suitable for all four types of questions we considered (effectiveness, harm, diagnosis and prognosis). None of the systems was considered usable for all of the target groups we considered (professionals, patients and policy makers). The raters found low reproducibility of judgements made using all six systems. Systems used by 51 organisations that sponsor clinical practice guidelines included a number of minor variations of the six systems that we critically appraised. Conclusions All of the currently used approaches to grading levels of evidence and the strength of recommendations have important shortcomings. PMID:15615589

  12. The Introduction of a New Grading System at a Public Teaching Institution: Impact on Grading Tendencies of the Faculty.

    ERIC Educational Resources Information Center

    Felder, Nathaniel L.

    The grading system at the University of North Carolina at Asheville before fall 1978 provided four designations: H (honors); G (good or well above average); P (pass or satisfactory); and F (failure). This range does not provide a grade for unsatisfactory but passing work. It was suspected that this led teachers to give "average" grades…

  13. Guidelines for application of fluorescent lamps in high-performance avionic backlight systems

    NASA Astrophysics Data System (ADS)

    Syroid, Daniel D.

    1997-07-01

    Fluorescent lamps have proven to be well suited for use in high performance avionic backlight systems as demonstrated by numerous production applications for both commercial and military cockpit displays. Cockpit display applications include: Boeing 777, new 737s, F-15, F-16, F-18, F-22, C- 130, Navy P3, NASA Space Shuttle and many others. Fluorescent lamp based backlights provide high luminance, high lumen efficiency, precision chromaticity and long life for avionic active matrix liquid crystal display applications. Lamps have been produced in many sizes and shapes. Lamp diameters range from 2.6 mm to over 20 mm and lengths for the larger diameter lamps range to over one meter. Highly convoluted serpentine lamp configurations are common as are both hot and cold cathode electrode designs. This paper will review fluorescent lamp operating principles, discuss typical requirements for avionic grade lamps, compare avionic and laptop backlight designs and provide guidelines for the proper application of lamps and performance choices that must be made to attain optimum system performance considering high luminance output, system efficiency, dimming range and cost.

  14. Liver transplantation for hepatocellular carcinoma: a proposal of a prognostic scoring system.

    PubMed

    Iwatsuki, S; Dvorchik, I; Marsh, J W; Madariaga, J R; Carr, B; Fung, J J; Starzl, T E

    2000-10-01

    The current staging system of hepatocellular carcinoma established by the International Union Against Cancer and the American Joint Committee on Cancer does not necessarily predict the outcomes after hepatic resection or transplantation. Various clinical and pathologic risk factors for tumor recurrence were examined on 344 consecutive patients who received hepatic transplantation in the presence of nonfibrolamellar hepatocellular carcinoma to establish a reliable risk scoring system. Multivariate analysis identified three factors as independently significant poor prognosticators: 1) bilobarly distributed tumors, 2) size of the greatest tumor (2 to 5 cm and > 5 cm), and 3) vascular invasion (microscopic and macroscopic). Prognostic risk score (PRS) of each patient was calculated from the relative risks of multivariate analysis. The patients were grouped into five grades of tumor recurrence risk: grade 1: PRS = 0 to < 7.5; grade 2: PRS = 7.5 to < or = 11.0; grade 3: PRS > 11.0 to 15.0; grade 4: PRS > or = 15.0; and grade 5: positive node, metastasis, or margin. The proposed PRS system correlated extremely well with tumor-free survival after liver transplantation (100%, 61%, 40%, 5%, and 0%, from grades 1 to 5, respectively, at 5 years), but current pTNM staging did not. 1) Patients with grades 1 and 2 are effectively treated with liver transplantation, 2) patients with grades 4 and 5 are poor candidates for liver transplantation, and 3) patients with grade 1 do not benefit from adjuvant chemotherapy.

  15. A 3-tier classification of cerebral arteriovenous malformations. Clinical article.

    PubMed

    Spetzler, Robert F; Ponce, Francisco A

    2011-03-01

    The authors propose a 3-tier classification for cerebral arteriovenous malformations (AVMs). The classification is based on the original 5-tier Spetzler-Martin grading system, and reflects the treatment paradigm for these lesions. The implications of this modification in the literature are explored. Class A combines Grades I and II AVMs, Class B are Grade III AVMs, and Class C combines Grades IV and V AVMs. Recommended management is surgery for Class A AVMs, multimodality treatment for Class B, and observation for Class C, with exceptions to the latter including recurrent hemorrhages and progressive neurological deficits. To evaluate whether combining grades is warranted from the perspective of surgical outcomes, the 3-tier system was applied to 1476 patients from 7 surgical series in which results were stratified according to Spetzler-Martin grades. Pairwise comparisons of individual Spetzler-Martin grades in the series analyzed showed the fewest significant differences (p < 0.05) in outcomes between Grades I and II AVMs and between Grades IV and V AVMs. In the pooled data analysis, significant differences in outcomes were found between all grades except IV and V (p = 0.38), and the lowest relative risks were found between Grades I and II (1.066) and between Grades IV and V (1.095). Using the pooled data, the predictive accuracies for surgical outcomes of the 5-tier and 3-tier systems were equivalent (receiver operating characteristic curve area 0.711 and 0.713, respectively). Combining Grades I and II AVMs and combining Grades IV and V AVMs is justified in part because the differences in surgical results between these respective pairs are small. The proposed 3-tier classification of AVMs offers simplification of the Spetzler-Martin system, provides a guide to treatment, and is predictive of outcome. The revised classification not only simplifies treatment recommendations; by placing patients into 3 as opposed to 5 groups, statistical power is markedly increased for series comparisons.

  16. The Application of the Novel Grading Scale (Lawton-Young Grading System) to Predict the Outcome of Brain Arteriovenous Malformation.

    PubMed

    Hafez, Ahmad; Koroknay-Pál, Päivi; Oulasvirta, Elias; Elseoud, Ahmed Abou; Lawton, Michael T; Niemelä, Mika; Laakso, Aki

    2018-05-04

    A supplementary grading scale (Supplemented Spetzler-Martin grade, Supp-SM) was introduced in 2010 as a refinement of the SM system to improve preoperative risk prediction of brain arteriovenous malformations (AVMs). To determine the ability to predict surgical outcomes using the Supp-SM grading scale. This retrospective study was conducted on 200 patients admitted to the Helsinki University Hospital between 2000 and 2014. The validity of the Supp-SM and SM grading systems was compared using the area under the receiver operating characteristic (AUROC) curves, with respect to the change between preoperative and early (3-4 mo) as well as final postoperative modified Rankin Scale (mRS) scores. The performance of the Supp-SM was superior to that of the SM grading scale in the early follow-up (3-4 mo): AUROC = 0.57 (95% confidence interval [CI]: 0.49-0.65) for SM and AUROC = 0.67 (95% CI: 0.60-0.75) for Supp-SM. The Supp-SM performance continued improving over SM at the late follow-up: AUROC = 0.63 (95% CI: 0.55-0.71) for SM and AUROC = 0.70 (95% CI: 0.62-0.77) for Supp-SM. The perforating artery supply, which is not part of either grading system, plays an important role in the early follow-up outcome (P = .008; odds ratio: 2.95; 95% CI: 1.32-6.55) and in the late follow-up outcome (P < .001; odds ratio: 5.89; 95% CI: 2.49-13.91). The Supp-SM grading system improves the outcome prediction accuracy and is a feasible alternative to the SMS, even for series with higher proportion of high-grade AVMs. However, perforators play important role on the outcome.

  17. Pan-European Grading Scales: Lessons from National Systems and the ECTS. The Bologna Process: Retrospect and Prospects

    ERIC Educational Resources Information Center

    Karran, Terence

    2005-01-01

    This article assesses the impact of the Bologna Process on the grading schemes of EU member countries. In light of some problems regarding the implementation of the European Credit Transfer system (ECTS), the author proposes further reforms and offers some elements of a unified grading system for European higher education. The author explores the…

  18. The distance effect in numerical memory-updating tasks.

    PubMed

    Lendínez, Cristina; Pelegrina, Santiago; Lechuga, Teresa

    2011-05-01

    Two experiments examined the role of numerical distance in updating numerical information in working memory. In the first experiment, participants had to memorize a new number only when it was smaller than a previously memorized number. In the second experiment, updating was based on an external signal, which removed the need to perform any numerical comparison. In both experiments, distance between the memorized number and the new one was manipulated. The results showed that smaller distances between the new and the old information led to shorter updating times. This graded facilitation suggests that the process by which information is substituted in the focus of attention involves maintaining the shared features between the new and the old number activated and selecting other new features to be activated. Thus, the updating cost may be related to amount of new features to be activated in the focus of attention.

  19. Site-specific tumor grading system in colorectal cancer: multicenter pathologic review of the value of quantifying poorly differentiated clusters.

    PubMed

    Ueno, Hideki; Hase, Kazuo; Hashiguchi, Yojiro; Shimazaki, Hideyuki; Tanaka, Masafumi; Miyake, Ohki; Masaki, Tadahiko; Shimada, Yoshifumi; Kinugasa, Yusuke; Mori, Yoshiyuki; Kishimoto, Mitsuo; Kameoka, Shingo; Sato, Yu; Matsuda, Keiji; Nakadoi, Koichi; Shinto, Eiji; Nakamura, Takahiro; Sugihara, Kenichi

    2014-02-01

    The study aimed to determine the value of a novel site-specific grading system based on quantifying poorly differentiated clusters (PDC; Grade(PDC)) in colorectal cancer (CRC). A multicenter pathologic review involving 12 institutions was performed on 3243 CRC cases (stage I, 583; II, 1331; III, 1329). Cancer clusters of ≥5 cancer cells and lacking a gland-like structure (PDCs) were counted under a ×20 objective lens in a field containing the maximum clusters. Tumors with <5, 5 to 9, and ≥10 PDCs were classified as grades G1, G2, and G3, respectively. According to Grade(PDC), 1594, 1005, and 644 tumors were classified as G1, G2, and G3 and had 5-year recurrence-free survival rates of 91.6%, 75.4%, and 59.6%, respectively (P<0.0001). Multivariate analysis showed that Grade exerted an influence on prognostic outcome independently of TNM staging; approximately 20% and 46% of stage I and II patients, respectively, were selected by Grade(PDC) as a population whose survival estimate was comparable to or even worse than that of stage III patients. Grade(PDC) surpassed TNM staging in the ability to stratify patients by recurrence-free survival (Akaike information criterion, 2915.6 vs. 2994.0) and had a higher prognostic value than American Joint Committee on Cancer (AJCC) grading (Grade(AJCC)) at all stages. Regarding judgment reproducibility of grading tumors, weighted κ among the 12 institutions was 0.40 for Grade(AJCC) and 0.52 for Grade(PDC). Grade(PDC) has a robust prognostic power and promises to be of sufficient clinical value to merit implementation as a site-specific grading system in CRC.

  20. Six of one, half a dozen of the other: A measure of multidisciplinary inter/intra-rater reliability of the society for fetal urology and urinary tract dilation grading systems for hydronephrosis.

    PubMed

    Rickard, Mandy; Easterbrook, Bethany; Kim, Soojin; Farrokhyar, Forough; Stein, Nina; Arora, Steven; Belostotsky, Vladamir; DeMaria, Jorge; Lorenzo, Armando J; Braga, Luis H

    2017-02-01

    The urinary tract dilation (UTD) classification system was introduced to standardize terminology in the reporting of hydronephrosis (HN), and bridge a gap between pre- and postnatal classification such as the Society for Fetal Urology (SFU) grading system. Herein we compare the intra/inter-rater reliability of both grading systems. SFU (I-IV) and UTD (I-III) grades were independently assigned by 13 raters (9 pediatric urology staff, 2 nephrologists, 2 radiologists), twice, 3 weeks apart, to 50 sagittal postnatal ultrasonographic views of hydronephrotic kidneys. Data regarding ureteral measurements and bladder abnormalities were included to allow proper UTD categorization. Ten images were repeated to assess intra-rater reliability. Krippendorff's alpha coefficient was used to measure overall and by grade intra/inter-rater reliability. Reliability between specialties and training levels were also analyzed. Overall inter-rater reliability was slightly higher for SFU (α = 0.842, 95% CI 0.812-0.879, in session 1; and α = 0.808, 95% CI 0.775-0.839, in session 2) than for UTD (α = 0.774, 95% CI 0.715-0.827, in session 1; and α = 0.679, 95% CI 0.605-0.750, in session 2). Reliability for intermediate grades (SFU II/III and UTD 2) of HN was poor regardless of the system. Reliabilities for SFU and UTD classifications among Urology, Nephrology, and Radiology, as well as between training levels were not significantly different. Despite the introduction of HN grading systems to standardize the interpretation and reporting of renal ultrasound in infants with HN, none have been proven superior in allowing clinicians to distinguish between "moderate" grades. While this study demonstrated high reliability in distinguishing between "mild" (SFU I/II and UTD 1) and "severe" (SFU IV and UTD 3) grades of HN, the overall reliability between specialties was poor. This is in keeping with a previous report of modest inter-rater reliability of the SFU system. This drawback is likely explained by the subjective interpretation required to assign grades, which can be impacted by experience, image quality, and scanning technique. As shown in the figure, which demonstrates SFU II (a) and SFU III (b), as assigned by a radiologist, it is possible to make an argument that either of these images can be classified into both categories that were observed during the grading sessions of this study. Although both systems have acceptable reliability, the SFU grading system showed higher overall intra/inter-rater reliability regardless of rater specialty than the UTD classification. Inter-rater reliability for SFU grades II/III and UTD 2 was low, highlighting the limitations of both classifications in regards to properly segregating moderate HN grades. Copyright © 2016 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.

  1. Accurate Estimate of Some Propagation Characteristics for the First Higher Order Mode in Graded Index Fiber with Simple Analytic Chebyshev Method

    NASA Astrophysics Data System (ADS)

    Dutta, Ivy; Chowdhury, Anirban Roy; Kumbhakar, Dharmadas

    2013-03-01

    Using Chebyshev power series approach, accurate description for the first higher order (LP11) mode of graded index fibers having three different profile shape functions are presented in this paper and applied to predict their propagation characteristics. These characteristics include fractional power guided through the core, excitation efficiency and Petermann I and II spot sizes with their approximate analytic formulations. We have shown that where two and three Chebyshev points in LP11 mode approximation present fairly accurate results, the values based on our calculations involving four Chebyshev points match excellently with available exact numerical results.

  2. Vibration analysis of FG cylindrical shells with power-law index using discrete singular convolution technique

    NASA Astrophysics Data System (ADS)

    Mercan, Kadir; Demir, Çiǧdem; Civalek, Ömer

    2016-01-01

    In the present manuscript, free vibration response of circular cylindrical shells with functionally graded material (FGM) is investigated. The method of discrete singular convolution (DSC) is used for numerical solution of the related governing equation of motion of FGM cylindrical shell. The constitutive relations are based on the Love's first approximation shell theory. The material properties are graded in the thickness direction according to a volume fraction power law indexes. Frequency values are calculated for different types of boundary conditions, material and geometric parameters. In general, close agreement between the obtained results and those of other researchers has been found.

  3. Effective use of e-grading in the dental simulation clinic.

    PubMed

    Morrow, Jay A; Pulido, M Teresa; Smith, P Bradford; McDaniel, Thomas F; Willcox, Austin B

    2014-06-01

    The purpose of this article is to describe the development and implementation of a grading software system, accessible from any platform, that engages today's generation of students and replaces paper grading. Set up at one U.S. dental school in an all-access, anytime (24/7) web-based program accessed through tablets, the software allows for a comparison between students' self-grading and instructor grading. This comparison facilitates student-faculty interaction, promoting discussion and student learning. The software can also be used for practical examination grading in which blinded grading between instructors is possible. The data gathered can produce descriptive reports students can draw upon to encourage self-learning and guided learning, propelling students to a better understanding of critical principles as they progress through multiple psychomotor skill sets. Other reports generated by the software allow for instructor calibration, exporting of grades directly into the university grading report system, and visual analysis of trends within each class. In a post-course survey, students (56 percent response rate) and faculty (79 percent response rate) agreed that the electronic grading was more efficient and allowed more time for faculty-student interaction than the previous grading system, thus creating an environment more conducive to learning. Overall, the software has improved students' perception of enhanced kinetic skills, while facilitating administration of preclinical projects and practical examinations.

  4. Test of the Center for Automated Processing of Hardwoods' Auto-Image Detection and Computer-Based Grading and Cutup System

    Treesearch

    Philip A. Araman; Janice K. Wiedenbeck

    1995-01-01

    Automated lumber grading and yield optimization using computer controlled saws will be plausible for hardwoods if and when lumber scanning systems can reliably identify all defects by type. Existing computer programs could then be used to grade the lumber, identify the best cut-up solution, and control the sawing machines. The potential value of a scanning grading...

  5. A Preliminary Investigation into the Effect of Standards-Based Grading on the Academic Performance of African-American Students

    NASA Astrophysics Data System (ADS)

    Bradbury-Bailey, Mary

    With the implementation of No Child Left Behind came a wave of educational reform intended for those working with student populations whose academic performance seemed to indicate an alienation from the educational process. Central to these reforms was the implementation of standards-based instruction and their accompanying standardized assessments; however, in one area reform seemed nonexistent---the teacher's gradebook. (Erickson, 2010, Marzano, 2006; Scriffiny, 2008). Given the link between the grading process and achievement motivation, Ames (1992) suggested the use of practices that promote mastery goal orientation. The purpose of this study was to examine the impact of standards-based grading system as a factor contributing to mastery goal orientation on the academic performance of urban African American students. To determine the degree of impact, this study first compared the course content averages and End-of-Course-Test (EOCT) scores for science classes using a traditional grading system to those using a standards-based grading system by employing an Analysis of Covariance (ANCOVA). While there was an increase in all grading areas, two showed a significant difference---the Physical Science course content average (p = 0.024) and ix the Biology EOCT scores (p = 0.0876). These gains suggest that standards-based grading can have a positive impact on the academic performance of African American students. Secondly, this study examined the correlation between the course content averages and the EOCT scores for both the traditional and standards-based grading system; for both Physical Science and Biology, there was a stronger correlation between these two scores for the standards-based grading system.

  6. Low-grade serous ovarian cancer: A review.

    PubMed

    Kaldawy, Anis; Segev, Yakir; Lavie, Ofer; Auslender, Ron; Sopik, Victoria; Narod, Steven A

    2016-11-01

    Epithelial ovarian cancers can be divided into the more common, aggressive type II cancers and the less common, slow-growing type I cancers. Under this model, serous ovarian carcinomas can be subdivided into high-grade (type II) and low-grade (type I) tumours. The two-tier system for grading serous ovarian carcinomas is superior to more detailed grading systems in terms of predicting survival. Low-grade serous carcinomas typically present in young women and have a relatively good prognosis, despite being resistant to chemotherapy. Low-grade serous cancers have a high prevalence of KRAS and BRAF mutations, but a low prevalence of TP53 mutations (which are characteristic of high-grade serous cancers). Among women with low-grade serous ovarian cancer, the presence of a KRAS/BRAF mutation is a favorable prognostic factor. Studies of the mitogen-activated protein kinase (MAPK) inhibitor in low-grade serous ovarian cancer suggest that identifying MAPK mutations might eventually be useful in guiding treatment. Copyright © 2016 Elsevier Inc. All rights reserved.

  7. Student Attitudes Toward Grades and Grading Practices.

    ERIC Educational Resources Information Center

    Stallings, William M.; Leslie, Elwood K.

    The result of a study designed to assess student attitudes toward grading practices are discussed. Questionnaire responses of 3439 students in three institutions were tabulated. Responses were generally negative toward conventional grading systems. (MS)

  8. Cataract prevalence varies substantially with assessment systems: comparison of clinical and photographic grading in a population-based study.

    PubMed

    Tan, Anna C S; Wang, Jie Jin; Lamoureux, Ecosse L; Wong, Wanling; Mitchell, Paul; Li, Jialiang; Tan, Ava Grace; Wong, Tien Y

    2011-08-01

    Cataract is the major cause of blindness worldwide yet there is no consensus on its assessment and definition. This study compares age-related cataract prevalence derived from two commonly used methods: clinical assessment using the Lens Opacity Classification System (LOCS III) and photographic grading using the Wisconsin Cataract Grading System (Wisconsin System). The Singapore Malay Eye Study is a population-based study of 3,280 Singapore Malays aged 40-80 years. Presence of nuclear, cortical and posterior sub-capsular cataract was assessed clinically during slit-lamp examination using LOCS III, and via slit-lamp and retro-illumination photographic grading using the Wisconsin System. Analyses were conducted to determine agreement in cataract prevalence estimates between the two grading Systems and approaches. Poor agreement was found between severity levels of the two grading scales for all three cataract types. Using currently accepted cut-offs to define nuclear (≥ 4 on both LOCS III and Wisconsin System), cortical (≥ 2 in LOCS III, ≥ 25% in Wisconsin) and PSC (≥ 2 in LOCS III, ≥ 5 % in Wisconsin) cataract, the LOCS III overestimated the prevalence of significant cataract as compared to the Wisconsin System, with nuclear cataract prevalence, 27.5% (LOCS III) versus 17.0% (Wisconsin System), cortical cataract prevalence, 27.9% versus 7.0% and posterior sub-capsular cataract prevalence, 7.8% versus 5.1%. The prevalence of cataract in a population varies substantially by measurement methods, with systematically different estimates found using the two most frequent cataract grading systems. This study re-emphasizes the need for global standards to assess and define cataract for epidemiologic and clinical studies.

  9. Does the Fuhrman or World Health Organization/International Society of Urological Pathology Grading System Apply to the Xp11.2 Translocation Renal Cell Carcinoma?: A 10-Year Single-Center Study.

    PubMed

    Liu, Ning; Gan, Weidong; Qu, Feng; Wang, Zhen; Zhuang, Wenyuan; Agizamhan, Sezim; Xu, Linfeng; Yin, Juanjuan; Guo, Hongqian; Li, Dongmei

    2018-04-01

    The Fuhrman and World Health Organization/International Society of Urological Pathology (WHO/ISUP) grading systems are widely used to predict survival for patients with conventional renal cell carcinoma. To determine the validity of nuclear grading systems (both the Fuhrman and the WHO/ISUP) and the individual components of the Fuhrman grading system in predicting the prognosis of Xp11.2 translocation renal cell carcinoma (Xp11.2 tRCC), we identified and followed up 47 patients with Xp11.2 tRCC in our center from January 2007 to June 2017. The Fuhrman and WHO/ISUP grading was reassigned by two pathologists. Nuclear size and shape were determined for each case based on the greatest degree of nuclear pleomorphism using image analysis software. Univariate and multivariate analyses were performed to evaluate the capacity of the grading systems and nuclear parameters to predict overall survival and progression-free survival. On univariate Cox regression analysis, the parameters of nuclear size were associated significantly with overall survival and progression-free survival, whereas the grading systems and the parameters of nuclear shape failed to reach a significant correlation. On multivariate analysis, however, none of the parameters was associated independently with survival. Our findings indicate that neither the Fuhrman nor the WHO/ISUP grading system is applicable to Xp11.2 tRCC. The assessment of nuclear size instead may be novel outcome predictors for patients with Xp11.2 tRCC. Copyright © 2018 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

  10. Thermomechanical response of metal-ceramic graded composites for high-temperature aerospace applications

    NASA Astrophysics Data System (ADS)

    Deierling, Phillip Eugene

    Airframes operating in the hypersonic regime are subjected to complex structural and thermal loads. Structural loads are a result of aggressive high G maneuvers, rapid vehicle acceleration and deceleration, and dynamic pressure, while thermal loads are a result of aerodynamic heating. For such airframes, structural members are typically constructed from steel, titanium and nickel alloys. However, with most materials, rapid elevations in temperature lead to undesirable changes in material properties. In particular, reductions in strength and stiffness are observed, along with an increase in thermal conductivity, specific heat and thermal expansion. Thus, hypersonic airframes are typically designed with external insulation, active cooling or a thermal protection system (TPS) added to the structure to protect the underling material from the effects of temperature. Such thermal protection may consist of adhesively bonded, pinned, and bolted thermal protection layers over exterior panels. These types of attachments create abrupt changes in thermal expansion and stiffness that make the structure susceptible to cracking and debonding as well as adding mass to the airframe. One of the promising materials concepts for extreme environments that was introduced in the past is the so-called Spatially Tailored Advanced Thermal Structures (STATS). The concept of STATS is rooted in functionally graded materials (FGMs), in which a directional variation of material properties exists. These materials are essentially composites and consist of two or more phases of distinct materials in which the volume fractions of each phase continuously change in space. Here, the graded material will serve a dual-purpose role as both the structural/skin member and thermal management with the goal of reducing the weight of the structure while maintaining structural soundness. This is achieved through the ability to tailor material properties to create a desired or enhanced thermomechanical response through spatial variation (e.g. grading). The objective of this study is to present a computational framework for modeling and evaluating the thermomechanical response of STATS and FGMs for highly maneuverable hypersonic (Mach > 5) airframes. To meet the objective of this study, four key steps have been defined to study the thermomechanical response of such materials in extreme environments. They involve: (1) modeling of graded microstructures; (2) validation of analytical and numerical modeling techniques for graded microstructures; (3) determination of effective properties of variable composition composites; (4) parametric studies to evaluate the performance of FGMs for use in the hypersonic operating environment; (5) optimization of the material spatial grading in hypersonic panels aiming to improve the thermomechanical performance. Modeling of graded microstructures, representing particulate reinforced FGMs, has been accomplished using power law distribution functions to specify the spatial variation of the constituents. Artificial microstructures consisting of disks and spheres have been generated using developed algorithms. These algorithms allow for the creation of dense packing fractions up to 0.61 and 0.91 for 2D and 3D geometry, respectively. Effective properties of FGMs are obtained using micromechanics models and finite element analysis of representative volume elements (RVEs). Two approaches have been adopted and compared to determine the proper RVE for materials with graded microstructures. In the first approach, RVEs are generated by considering regions that have a uniform to slow variation in material composition (i.e., constant volume fraction), resulting in statistically homogenous piecewise RVEs of the graded microstructure neglecting interactions from neighboring cells. In the second approach, continuous RVEs are generated by considering the entire FGM. Here it is presumed that modeling of the complete variation in a microstructure may influence the surrounding layers due to the interactions of varying material composition, particularly when there is a steep variation in material composition along the grading direction. To determine these effects of interlayer interactions, FGM microstructures were generated using three different types of material grading functions, linear, quadratic and square root, providing uniform, gradual and steep variations, respectively. Two- and three-dimensional finite element analysis was performed to determine the effective temperature-dependent material properties of the composite over a wide temperature range. The outcome of the computational analysis show that the similar effective properties are obtained by each of the modeling approaches. Furthermore, the obtained computational results for effective elastic, thermal, and thermal expansion properties are consistent with the known analytical bounds. Resulting effective temperature-dependent material properties were used to evaluate the time-dependent thermostructural response and effectiveness of FGM structural panels. Structural panels are subjected to time- and spatial-dependent thermal and mechanical loads resulting from hypersonic flight over a representative trajectory. Mechanical loads are the by-product of aggressive maneuvering at high air speeds and angles of attack. Thermal loads as a result of aerodynamic heating are applied to the material systems as laminar, turbulent and transitional heat flux on the outer surface. Laminar and turbulent uniform heat fluxes are used to evaluate the effectiveness of FGM panels graded in the through-thickness direction only. Transitional heat fluxes are used to evaluate the effectiveness of FGMs graded in two principal directions, e.g., through-thickness and the surface parallel to flow. The computational results indicate that when subjected to uniform surface heat flux, the graded material system can eliminate through-thickness temperature gradients that are otherwise present in traditional thermal protection systems. Furthermore, two-dimensional graded material systems can also eliminate through-thickness temperature gradients and significantly reduce in-plane surface temperature gradients when subjected to non-uniform surface aerodynamic heating.

  11. The dysfunctional consequences of a performance measurement system: the case of the Iranian national hospital grading programme.

    PubMed

    Aryankhesal, Aidin; Sheldon, Trevor A; Mannion, Russell; Mahdipour, Saeade

    2015-07-01

    Performance measurement systems are increasingly used to reward and improve provider performance. However, such initiatives may also inadvertently induce a range of unintended and dysfunctional side-effects. This study explores the unintended and adverse consequences induced by the Iranian national hospital grading programme, which incorporates financial incentives for meeting nationally defined standards. We interviewed key informants across four key groups with a legitimate interest in healthcare performance: four purposively selected hospitals; four health insurance organizations; the Iranian hospital accreditation body; and one grading agency. The transcribed interviews and field notes were analysed thematically, and subsequently, member checking was conducted. Seven dysfunctional consequences were identified: misrepresentation of data by hospitals; increased anxiety and stress among hospital employees; tunnel vision; financial pressures on poorly graded hospitals; incentives to purchase unnecessary equipment; erosion of public trust; and restricting access to hospital services by patients. These were caused by the way the grading system was implemented: poor standards of audit; the way in which the audit process was conducted; and the timing of audits. The pay for performance element of the grading system and the focus on structural aspects in the standards made improvement in grading particularly difficult for those hospitals that had been assessed as under-performing. Although the Iranian hospital grading system has resulted in a significant increase in the adoption of national standards, it has nevertheless induced a range of perverse outcomes. To mitigate these requires further refinement and recalibration of the system. © The Author(s) 2015.

  12. Clear cell renal cell carcinoma: validation of World Health Organization/International Society of Urological Pathology grading.

    PubMed

    Dagher, Julien; Delahunt, Brett; Rioux-Leclercq, Nathalie; Egevad, Lars; Srigley, John R; Coughlin, Geoffrey; Dunglinson, Nigel; Gianduzzo, Troy; Kua, Boon; Malone, Greg; Martin, Ben; Preston, John; Pokorny, Morgan; Wood, Simon; Yaxley, John; Samaratunga, Hemamali

    2017-12-01

    In 2012, the International Society of Urological Pathology (ISUP) introduced a novel grading system for clear cell renal cell carcinoma (ccRCC) and papillary renal cell carcinoma. This system is incorporated into the latest World Health Organization renal tumour classification, being designated WHO/ISUP grading. This study was undertaken to compare WHO/ISUP and Fuhrman grading and to validate WHO/ISUP grading as a prognostic parameter in a series of clear cell RCC. Analysis of 681 cases of ccRCC showed that 144 tumours could not be assigned a Fuhrman grade on the basis of ambiguous grading features. The application of WHO/ISUP grading resulted in a general down-grading of cases when compared with Fuhrman grading. In a sub-group of 374 cases, for which outcome data were available, 9.3% were WHO/ISUP grade 1, 50.3% were grade 2, 24.1% grade 3 and 16.3% grade 4, while the distribution of Fuhrman grades was 0.4% grade 1, 48.7% grade 2, 29.4% grade 3 and 21.5% grade 4. There were no recurrence/metastases amongst patients with WHO/ISUP grade 1 tumours and there was a significant difference in outcome for WHO/ISUP grades 2, 3 and 4. For Fuhrman grading the cancer-free survival was not significantly different for grade 2 and grade 3 tumours. On multivariate analysis WHO/ISUP grade and pT staging category were found to retain prognostic significance. The study demonstrates that FG cannot be applied in >20% of cases of ccRCC and the WHO/ISUP provides superior prognostic information. © 2017 John Wiley & Sons Ltd.

  13. Vibration analysis and transient response of a functionally graded piezoelectric curved beam with general boundary conditions

    NASA Astrophysics Data System (ADS)

    Su, Zhu; Jin, Guoyong; Ye, Tiangui

    2016-06-01

    The paper presents a unified solution for free and transient vibration analyses of a functionally graded piezoelectric curved beam with general boundary conditions within the framework of Timoshenko beam theory. The formulation is derived by means of the variational principle in conjunction with a modified Fourier series which consists of standard Fourier cosine series and supplemented functions. The mechanical and electrical properties of functionally graded piezoelectric materials (FGPMs) are assumed to vary continuously in the thickness direction and are estimated by Voigt’s rule of mixture. The convergence, accuracy and reliability of the present formulation are demonstrated by comparing the present solutions with those from the literature and finite element analysis. Numerous results for FGPM beams with different boundary conditions, geometrical parameters as well as material distributions are given. Moreover, forced vibration of the FGPM beams subjected to dynamic loads and general boundary conditions are also investigated.

  14. Analysis of Photothermal Characterization of Layered Materials: Design of Optimal Experiments

    NASA Technical Reports Server (NTRS)

    Cole, Kevin D.

    2003-01-01

    In this paper numerical calculations are presented for the steady-periodic temperature in layered materials and functionally-graded materials to simulate photothermal methods for the measurement of thermal properties. No laboratory experiments were performed. The temperature is found from a new Green s function formulation which is particularly well-suited to machine calculation. The simulation method is verified by comparison with literature data for a layered material. The method is applied to a class of two-component functionally-graded materials and results for temperature and sensitivity coefficients are presented. An optimality criterion, based on the sensitivity coefficients, is used for choosing what experimental conditions will be needed for photothermal measurements to determine the spatial distribution of thermal properties. This method for optimal experiment design is completely general and may be applied to any photothermal technique and to any functionally-graded material.

  15. Alternative scheduling models and their effect on science achievement at the high school level

    NASA Astrophysics Data System (ADS)

    Dostal, Jay Roland

    This study will evaluate alternative scheduling methods implemented in secondary level schools. Students were selected based on parent selection of programs. Traditional scheduling involves numerous academic subjects with small increments of time in each class and block scheduling focuses on fewer academic subjects and more instructional time. This study will compare office referral numbers, absence frequency, and Essential Learner Outcome (ELO) science strand scores in the 8th-grade (pretest) to the same students office referrals, absence frequency, and ELO science strand scores in the 11th-grade (posttest) between Seven Period Traditional Scheduling (SPTS) and Four Period Block Scheduling (FPBS) in the hopes that no matter what schedule students are a part of, the achievement results will be similar. (Study participants had completed both grade level ELO assessments and were continuously enrolled in one high school through their junior year.

  16. Multi-Method Assessment of Metacognitive Skills in Elementary School Children: How You Test Is What You Get

    ERIC Educational Resources Information Center

    Desoete, Annemie

    2008-01-01

    Third grade elementary school children solved tests on mathematical reasoning and numerical facility. Metacognitive skillfulness was assessed through think aloud protocols, prospective and retrospective child ratings, teacher questionnaires, calibration measures and EPA2000. In our dataset metacognition has a lot in common with intelligence, but…

  17. Development of Conceptually Focused Early Numeracy Skill Indicators

    ERIC Educational Resources Information Center

    Methe, Scott A.; Begeny, John C.; Leary, Lemontrel L.

    2011-01-01

    This research was conducted to evaluate the technical properties of a set of early numeracy CBM tests that were designed to operationalize early numeric concepts. Data were collected over the course of a school year from 113 kindergarten and first-grade children using nine separate tests with three alternative forms. In addition, test-retest…

  18. Implementing an Imaginative Unit: Wonders of the Water Cycle

    ERIC Educational Resources Information Center

    Hrennikoff, Margo

    2006-01-01

    The grade three curriculum set out by the British Columbia Ministry of Education has four categories for science: Processes of Science, Life Science, Physical Science, and Earth and Space Science. Within each of these categories there are numerous topics to teach. For example, the physical science curriculum requires students to learn about…

  19. Evaluation of feed grade sodium bisulfate impact on gastrointestinal tract microbiota ecology in broilers via a pyrosequencing platform

    USDA-ARS?s Scientific Manuscript database

    The gastrointestinal microbial community in broiler chicken consists of many different species of bacteria and the overall microbiota can be various from bird to bird. In order to control pathogenic bacteria in broiler and improve gut health, numerous potential dietary amendments such as prebiotics...

  20. xyZET: A Simulation Program for Physics Teaching.

    ERIC Educational Resources Information Center

    Hartel, Hermann

    2000-01-01

    Discusses xyZET, a simulation program that allows 3D-space in numerous experiments in basic mechanics and electricity and was developed to support physics teaching. Tests course material for 11th grade at German high schools under classroom conditions and reports on their stability and effectiveness. (Contains 15 references.) (Author/YDS)

  1. Teaching Students Financial Literacy Using the Internet

    ERIC Educational Resources Information Center

    Risinger, C. Frederick

    2009-01-01

    As the author researched the causes and implications of the current economic crisis, he came across numerous commentaries on how financial literacy was seldom taught (or taught well) in U.S. schools. This article, aimed at teachers and supervisors at all grade levels, describes some Internet sites that: (1) explain the collapse of the housing…

  2. Functions and the Volume of Vases

    ERIC Educational Resources Information Center

    McCoy, Ann C.; Barger, Rita H.; Barnett, Joann; Combs, Emily

    2012-01-01

    Functions are one of the most important and powerful tools in mathematics because they allow the symbolic, visual, and verbal representation of relationships between variables. The power of functions, as well as the numerous real-world uses of functions, make them an important part of the development of algebraic reasoning in the middle grades.…

  3. Powering the Future: A Wind Turbine Design Challenge

    ERIC Educational Resources Information Center

    Pries, Caitlin Hicks; Hughes, Julie

    2011-01-01

    Nothing brings out the best in eighth-grade physical science students quite like an engineering challenge. The wind turbine design challenge described in this article has proved to be a favorite among students with its focus on teamwork and creativity and its (almost) sneaky reinforcement of numerous physics concepts. For this activity, pairs of…

  4. Analyzing Algebraic Thinking Using "Guess My Number" Problems

    ERIC Educational Resources Information Center

    Patton, Barba; De Los Santos, Estella

    2012-01-01

    The purpose of this study was to assess student knowledge of numeric, visual and algebraic representations. A definite gap between arithmetic and algebra has been documented in the research. The researchers' goal was to identify a link between the two. Using four "Guess My Number" problems, seventh and tenth grade students were asked to write…

  5. Identifying Simple Numerical Stimuli: Processing Inefficiencies Exhibited by Arithmetic Learning Disabled Children.

    ERIC Educational Resources Information Center

    Koontz, Kristine L.; Berch, Daniel B.

    1996-01-01

    Children with arithmetic learning disabilities (n=16) and normally achieving controls (n=16) in grades 3-5 were administered a battery of computerized tasks. Memory spans for both letters and digits were found to be smaller among the arithmetic learning disabled children. Implications for teaching are discussed. (Author/CMS)

  6. Changes in Student Science Interest from Elementary to Middle School

    ERIC Educational Resources Information Center

    Coutts, Trudi E.

    2012-01-01

    This study is a transcendental phenomenological study that described the experience of students' interest in science from elementary school through middle school grades and the identification of the factors that increase or decrease interest in science. Numerous researchers have found that interest in science changes among children and the change…

  7. Health Activities Project (HAP), Trial Edition III.

    ERIC Educational Resources Information Center

    Buller, Dave; And Others

    Contained within this Health Activities Project (HAP) trial edition (set III) are a teacher information folio and numerous student activity folios which center around the idea that students in grades 5-8 can control their own health and safety. Each student folio is organized into an Overview, Health Background, Materials, Setting Up, and…

  8. Health Activities Project (HAP), Trial Edition II.

    ERIC Educational Resources Information Center

    Buller, Dave; And Others

    Contained within this Health Activities Project (HAP) trial edition (set II) are a teacher information folio and numerous student activity folios which center around the idea that students in grades 5-8 can control their own health and safety. Each student folio is organized into a Synopsis, Health Background, Materials, Setting Up, and Activities…

  9. On the Factorial Structure of the SAT and Implications for Next-Generation College Readiness Assessments

    ERIC Educational Resources Information Center

    Wiley, Edward W.; Shavelson, Richard J.; Kurpius, Amy A.

    2014-01-01

    The name "SAT" has become synonymous with college admissions testing; it has been dubbed "the gold standard." Numerous studies on its reliability and predictive validity show that the SAT predicts college performance beyond high school grade point average. Surprisingly, studies of the factorial structure of the current version…

  10. Impact of the Child Development Program on Reading Achievement of Kindergarten through Eighth Grade Students in an Urban School District

    ERIC Educational Resources Information Center

    Lynch, Tai E.

    2013-01-01

    Educational leaders are charged with making informed decisions regarding various aspects of schooling that affect the overall achievement of students. Numerous legislative ideas, funding initiatives, programming standards, and practicing guidelines for early childhood education programs have been introduced (Buyssee & Wesley, 2006). Early care…

  11. Native Americans of Washington State (A Curriculum Guide for Elementary Grades). First Edition.

    ERIC Educational Resources Information Center

    Forsyth, Karen Williams; Neal, Colleen

    Developed as a supplemental curriculum guide for elementary teachers, the guide assists in implementing Native American activities to classroom curriculum to make students aware of the numerous tribes within the state of Washington. Divided in three geographic, cultural areas (Northwest Coast region, Puget Sound Lowlands region, and Plateau…

  12. Integrating Pharmacology Topics in High School Biology and Chemistry Classes Improves Performance

    ERIC Educational Resources Information Center

    Schwartz-Bloom, Rochelle D.; Halpin, Myra J.

    2003-01-01

    Although numerous programs have been developed for Grade Kindergarten through 12 science education, evaluation has been difficult owing to the inherent problems conducting controlled experiments in the typical classroom. Using a rigorous experimental design, we developed and tested a novel program containing a series of pharmacology modules (e.g.,…

  13. Learner Participation in the Functions Discourse: A Focus on Asymptotes of the Hyperbola

    ERIC Educational Resources Information Center

    Mpofu, Sihlobosenkosi; Pournara, Craig

    2018-01-01

    The study investigated learners' mathematical discourse on the hyperbola from a commognitive perspective, and focused on algebraic, graphic, and numeric representations of the hyperbola. Task-based interviews were conducted with five Grade 10 learners from a township school. Learners' mathematical discourse was analysed by means of the Discourse…

  14. Microcomputer Keyboarding Curriculum for Middle and Junior High School Students. Final Report.

    ERIC Educational Resources Information Center

    Regional School District No. 10, Burlington, CT.

    This project report describes the development of a seventh-grade curriculum to promote microcomputer keyboarding skills, i.e., learning correct alpha-numeric reaches, developing proficiency in making appropriate reaches, using correct fingering without looking at the keyboard, and attaining a degree of speed and accuracy. Although the curriculum…

  15. Later Language Development: The School-Age and Adolescent Years. Second Edition.

    ERIC Educational Resources Information Center

    Nippold, Marilyn A.

    This book focuses on the more advanced language abilities of upper grade youth and adolescents. It discusses how language develops from childhood to adulthood. The book compiles, integrates, and interprets the extensive research on this population for numerous topics. It is useful to anyone seeking an increased understanding of the relationships…

  16. How Big Is a 16-Penny Nail? A Measurement Lesson for Middle Grades

    ERIC Educational Resources Information Center

    Engel, Bill; Schmidt, Diane L.

    2004-01-01

    Many common objects can provide numerous opportunities for students to develop mathematical concepts and skills. The lesson described in this article provided an excellent opportunity for middle school students to discover how real-life situations do not always present obvious "right" answers. As students explored a question related to the…

  17. Some Effects of Distractions in Nonverbal Mathematical Problems

    ERIC Educational Resources Information Center

    Bana, J. P.; Nelson, D.

    1977-01-01

    The central purpose of this study was to investigate the effects of distractions in nonverbal problems on the problem solving behavior and performance of young children (grades 1-3) in 6 schools (N=360). Results indicated 66 percent of the subjects were distracted by irrelevant spatial-numerical or color attribute uses. (JC)

  18. Multimode optical fiber

    DOEpatents

    Bigot-Astruc, Marianne; Molin, Denis; Sillard, Pierre

    2014-11-04

    A depressed graded-index multimode optical fiber includes a central core, an inner depressed cladding, a depressed trench, an outer depressed cladding, and an outer cladding. The central core has an alpha-index profile. The depressed claddings limit the impact of leaky modes on optical-fiber performance characteristics (e.g., bandwidth, core size, and/or numerical aperture).

  19. A Modified Kirchhoff plate theory for Free Vibration analysis of functionally graded material plates using meshfree method

    NASA Astrophysics Data System (ADS)

    Nguyen Van Do, Vuong

    2018-04-01

    In this paper, a modified Kirchhoff theory is presented for free vibration analyses of functionally graded material (FGM) plate based on modified radial point interpolation method (RPIM). The shear deformation effects are taken account into modified theory to ignore the locking phenomenon of thin plates. Due to the proposed refined plate theory, the number of independent unknowns reduces one variable and exists with four degrees of freedom per node. The simulated free vibration results employed by the modified RPIM are compared with the other analytical solutions to verify the effectiveness and the accuracy of the developed mesh-free method. Detail parametric studies of the proposed method are then conducted including the effectiveness of thickness ratio, boundary condition and material inhomogeneity on the sample problems of square plates. Results illustrated that the modified mesh-free RPIM can effectively predict the numerical calculation as compared to the exact solutions. The obtained numerical results are indicated that the proposed method are stable and well accurate prediction to evaluate with other published analyses.

  20. Modeling of power transmission and stress grading for corona protection

    NASA Astrophysics Data System (ADS)

    Zohdi, T. I.; Abali, B. E.

    2017-11-01

    Electrical high voltage (HV) machines are prone to corona discharges leading to power losses as well as damage of the insulating layer. Many different techniques are applied as corona protection and computational methods aid to select the best design. In this paper we develop a reduced-order model in 1D estimating electric field and temperature distribution of a conductor wrapped with different layers, as usual for HV-machines. Many assumptions and simplifications are undertaken for this 1D model, therefore, we compare its results to a direct numerical simulation in 3D quantitatively. Both models are transient and nonlinear, giving a possibility to quickly estimate in 1D or fully compute in 3D by a computational cost. Such tools enable understanding, evaluation, and optimization of corona shielding systems for multilayered coils.

  1. Histopathological grading of breast ductal carcinoma in situ: validation of a web-based survey through intra-observer reproducibility analysis.

    PubMed

    Schuh, Fernando; Biazús, Jorge Villanova; Resetkova, Erika; Benfica, Camila Zanella; Ventura, Alessandra de Freitas; Uchoa, Diego; Graudenz, Márcia; Edelweiss, Maria Isabel Albano

    2015-07-10

    Histopathological grading diagnosis of ductal carcinoma in situ (DCIS) of the breast may be very difficult even for experts, and it is important for therapeutic decisions. The challenge may be due to the inaccurate and/or subjective application of the diagnosis criteria. The aim of this study was to investigate the intra-observer agreement between a traditional method and a developed web-based questionnaire for scoring breast DCIS. A cross-sectional study was carried out to evaluate the diagnostic agreement of an electronic questionnaire and its point scoring system with the subjective reading of digital images for 3 different DCIS grading systems: Holland, Van Nuys and modified Black nuclear grade system. Three pathologists analyzed the same set of digitized images from 43 DCIS cases using two different web-based programs. In the first phase, they accessed a website with a newly created questionnaire and scoring system developed to allow the determination of the histological grade of the cases. After at least 6 months, the pathologists read again the same images, but without the help of the questionnaire, indicating subjectively the diagnoses. The intra-observer agreement analysis was employed to validate this innovative web-based survey. Overall, diagnostic reproducibility was similar for all histologic grading classification systems, with kappa values of 0.57 ± 0.10, 0.67 ± 0.09 and 0.67 ± 0.09 for Holland, Van Nuys classification and modified Black nuclear grade system respectively. Only two 2-step diagnostic disagreements were found, one for Holland and another for Van Nuys. Both cases were superestimated by the web-based survey. The diagnostic agreement between the web-based questionnaire and a traditional method, both using digital images, is moderate to good for Holland, Van Nuys and modified Black nuclear grade system. The use of a scoring point system does not appear to pose a major risk of presenting large (2-step) diagnostic disagreements. These findings indicate that the use of this point scoring system in this web-based survey to grade objectively DCIS lesions is a useful diagnostic tool.

  2. Goseki grade and tumour location influence survival of patients with gastric cancer.

    PubMed

    Calik, Muhammet; Calik, Ilknur; Demirci, Elif; Altun, Eren; Gundogdu, Betul; Sipal, Sare; Gundogdu, Cemal

    2014-01-01

    Owing to the variability of histopathological features and biological behaviour in gastric carcinoma, a great number of categorisation methods such as classical histopathologic grading, Lauren classification, the TNM staging system and the newly presented Goseki grading method are used by pathologists and other scientists. In our study, we aimed to investigate whether Goseki grade and tumour location have an effects on survival of gastric cancer cases. Eighty-four patients with gastric adenocarcinoma were covered in the investigation. The importance of Goseki grading system and tumour location were analysed in addition to the TNM staging and other conventional prognostic parameters. The median survival time in our patients was 35 months (minimum: 5, maximum: 116). According to our findings, there was no relation between survival and tumour size (p=0.192) or classical histological type (p=0.270). In contrast, the Goseki grade and tumour location significantly correlated with survival (p=0.007 and p<0.001, respectively). Additionally, tumours of the intestinal type had a longer median survival time (60.0 months) than diffuse tumours (24.0 months). In addition to the TNM staging system, tumour location and the Goseki grading system may be used as significant prognostic parameters in patients with gastric cancer.

  3. Automatic Grading of Spreadsheet and Database Skills

    ERIC Educational Resources Information Center

    Kovacic, Zlatko J.; Green, John Steven

    2012-01-01

    Growing enrollment in distance education has increased student-to-lecturer ratios and, therefore, increased the workload of the lecturer. This growing enrollment has resulted in mounting efforts to develop automatic grading systems in an effort to reduce this workload. While research in the design and development of automatic grading systems has a…

  4. Improving the prediction of the final part geometry in high strength steels U drawing by means of advanced material and friction models

    NASA Astrophysics Data System (ADS)

    de Argandoña, Eneko Saenz; Mendiguren, Joseba; Otero, Irune; Mugarra, Endika; Otegi, Nagore; Galdos, Lander

    2018-05-01

    Steel has been used in vehicles from the automotive industry's inception. Different steel grades are continually being developed in order to satisfy new fuel economy requirements. For example, advanced high strength steel grades (AHSS) are widely used due to their good strength/weight ratio. Because each steel grade has a different microstructure composition and hardness, they show different behaviors when they are subjected to different strain paths. Similarly, the friction behavior when using different contact pressures is considerably altered. In the present paper, four different steel grades, ZSt380, DP600, DP780 and Fortiform 1050 materials are deeply characterized using uniaxial and cyclic tension-compression tests. Coefficient of friction (COF) is also obtained using strip drawing tests. These results have been used to calibrate mixed kinematic-hardening material models as well as pressure dependent friction models. Finally, the geometrical accuracy of the different material and friction models has been evaluated by comparing the numerical predictions with experimental demonstrators obtained using a U-Drawing tester.

  5. Investigation of free vibration analysis of functionally graded annular piezoelectric plate using COMSOL

    NASA Astrophysics Data System (ADS)

    Sharma, Trivendra Kumar; Parashar, Sandeep Kumar

    2018-05-01

    In the present age functionally graded piezoelectric materials (FGPM) are increasingly being used as actuators and sensors. In spite of the fact that the piezoelectric coupling coefficient for shear d15 has much higher value in comparison to d31 or d33, it is far less utilized for the applications due to complex nature of the shear induced vibrations. In this work three dimensional free vibration analysis of functionally graded piezoelectric material annular plates with free-free boundary conditions is presented. The annular FGPM plate is polarized along the radial direction while the electric field is applied along the thickness direction inducing flexural vibrations of the plate due to d15 effect of functionally graded piezoelectric materials. The material properties are assumed to have a power law variation along the thickness. COMSOL Multiphysics is used to obtain the natural frequencies and modeshapes. Detailed numerical study is performed to ascertain the effect of variation in power law index and various geometrical parameters. The results presented shall be helpful in optimizing the existing applications and developing the new ones utilizing the FGPM annular plates.

  6. Visual tree grading systems for estimating lumber yields in young and mature southern pine

    Treesearch

    Alexander Clark; Robert H. McAlister

    1998-01-01

    New visual tree grading systems for mature southern pine ? 35 years old and young pine ? 35 years old based on number and size of branches in the lower bole are described. A series of lumber grade yield studies was conducted to test the new grading rules. A total of 214 natural loblolly pine (Pinus taeda L.) and shortleaf pine (P. echinata Mill) trees 9 to 20 inches...

  7. Lightweight armor system and process for producing the same

    DOEpatents

    Chu, Henry S.; Bruck, H. Alan; Strempek, Gary C.; Varacalle, Jr., Dominic J.

    2004-01-20

    A lightweight armor system may comprise a substrate having a graded metal matrix composite layer formed thereon by thermal spray deposition. The graded metal matrix composite layer comprises an increasing volume fraction of ceramic particles imbedded in a decreasing volume fraction of a metal matrix as a function of a thickness of the graded metal matrix composite layer. A ceramic impact layer is affixed to the graded metal matrix composite layer.

  8. Prognostic Performance and Reproducibility of the 1973 and 2004/2016 World Health Organization Grading Classification Systems in Non-muscle-invasive Bladder Cancer: A European Association of Urology Non-muscle Invasive Bladder Cancer Guidelines Panel Systematic Review.

    PubMed

    Soukup, Viktor; Čapoun, Otakar; Cohen, Daniel; Hernández, Virginia; Babjuk, Marek; Burger, Max; Compérat, Eva; Gontero, Paolo; Lam, Thomas; MacLennan, Steven; Mostafid, A Hugh; Palou, Joan; van Rhijn, Bas W G; Rouprêt, Morgan; Shariat, Shahrokh F; Sylvester, Richard; Yuan, Yuhong; Zigeuner, Richard

    2017-11-01

    Tumour grade is an important prognostic indicator in non-muscle-invasive bladder cancer (NMIBC). Histopathological classifications are limited by interobserver variability (reproducibility), which may have prognostic implications. European Association of Urology NMIBC guidelines suggest concurrent use of both 1973 and 2004/2016 World Health Organization (WHO) classifications. To compare the prognostic performance and reproducibility of the 1973 and 2004/2016 WHO grading systems for NMIBC. A systematic literature search was undertaken incorporating Medline, Embase, and the Cochrane Library. Studies were critically appraised for risk of bias (QUIPS). For prognosis, the primary outcome was progression to muscle-invasive or metastatic disease. Secondary outcomes were disease recurrence, and overall and cancer-specific survival. For reproducibility, the primary outcome was interobserver variability between pathologists. Secondary outcome was intraobserver variability (repeatability) by the same pathologist. Of 3593 articles identified, 20 were included in the prognostic review; three were eligible for the reproducibility review. Increasing tumour grade in both classifications was associated with higher disease progression and recurrence rates. Progression rates in grade 1 patients were similar to those in low-grade patients; progression rates in grade 3 patients were higher than those in high-grade patients. Survival data were limited. Reproducibility of the 2004/2016 system was marginally better than that of the 1973 system. Two studies on repeatability showed conflicting results. Most studies had a moderate to high risk of bias. Current grading classifications in NMIBC are suboptimal. The 1973 system identifies more aggressive tumours. Intra- and interobserver variability was slightly less in the 2004/2016 classification. We could not confirm that the 2004/2016 classification outperforms the 1973 classification in prediction of recurrence and progression. This article summarises the utility of two different grading systems for non-muscle-invasive bladder cancer. Both systems predict progression and recurrence, although pathologists vary in their reporting; suggestions for further improvements are made. Copyright © 2017 European Association of Urology. Published by Elsevier B.V. All rights reserved.

  9. Is the Sky Falling? Grade Inflation and the Signaling Power of Grades

    ERIC Educational Resources Information Center

    Pattison, Evangeleen; Grodsky, Eric; Muller, Chandra

    2013-01-01

    Grades are the fundamental currency of our educational system; they signal academic achievement and noncognitive skills to parents, employers, postsecondary gatekeepers, and students themselves. Grade inflation compromises the signaling value of grades and undermines their capacity to achieve the functions for which they are intended. We challenge…

  10. 5 CFR 842.206 - Involuntary retirement.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ...; and (iv) Not lower than the equivalent of two grades or pay levels below the employee's current grade or pay level, without consideration of the employee's eligibility to retain his or her current grade... systems, the comparison rate of the grade or pay level that is two grades below that of the current...

  11. The Grades Transfer from One Grading Scale to Other Algorithmization

    ERIC Educational Resources Information Center

    Lieponiene, Jurgita; Kulvietiene, Regina

    2011-01-01

    The article presents the consideration of grading scales used for education outcomes in different countries, describes likeness and differences of applied grading scales. Application of the European Credit Transfer and Accumulation System (ECTS) grading scale is investigated according of the analysis of scientific literature as well as cases of…

  12. Computer-Aided Grading of Lymphangioleiomyomatosis (LAM) using HRCT

    PubMed Central

    Yao, Jianhua; Avila, Nilo; Dwyer, Andrew; Taveira-DaSilva, Angelo M.; Hathaway, Olanda M.; Moss, Joel

    2010-01-01

    Lymphangioleiomyomatosis (LAM) is a multisystem disorder associated with proliferation of smooth muscle-like cells, which leads to destruction of lung parenchyma. Subjective grading of LAM on HRCT is imprecise and can be arduous especially in cases with severe involvement. We propose a computer-aided evaluation system that grades LAM involvement based on analysis of lung texture patterns. A committee of support vector machines is employed for classification. The system was tested on 36 patients. The computer grade demonstrates good correlation with subjective radiologist grade (R=0.91, p<0.0001) and pulmonary functional tests (R=0.85, p<0.0001). The grade also provides precise progression assessment of disease over time. PMID:21625320

  13. Assessment of automated disease detection in diabetic retinopathy screening using two-field photography.

    PubMed

    Goatman, Keith; Charnley, Amanda; Webster, Laura; Nussey, Stephen

    2011-01-01

    To assess the performance of automated disease detection in diabetic retinopathy screening using two field mydriatic photography. Images from 8,271 sequential patient screening episodes from a South London diabetic retinopathy screening service were processed by the Medalytix iGrading™ automated grading system. For each screening episode macular-centred and disc-centred images of both eyes were acquired and independently graded according to the English national grading scheme. Where discrepancies were found between the automated result and original manual grade, internal and external arbitration was used to determine the final study grades. Two versions of the software were used: one that detected microaneurysms alone, and one that detected blot haemorrhages and exudates in addition to microaneurysms. Results for each version were calculated once using both fields and once using the macula-centred field alone. Of the 8,271 episodes, 346 (4.2%) were considered unassessable. Referable disease was detected in 587 episodes (7.1%). The sensitivity of the automated system for detecting unassessable images ranged from 97.4% to 99.1% depending on configuration. The sensitivity of the automated system for referable episodes ranged from 98.3% to 99.3%. All the episodes that included proliferative or pre-proliferative retinopathy were detected by the automated system regardless of configuration (192/192, 95% confidence interval 98.0% to 100%). If implemented as the first step in grading, the automated system would have reduced the manual grading effort by between 2,183 and 3,147 patient episodes (26.4% to 38.1%). Automated grading can safely reduce the workload of manual grading using two field, mydriatic photography in a routine screening service.

  14. Reduction effect of the quantity of radiation exposure and contrast media by image support system in transarterial chemoembolization for the treatment of hepatocellular carcinoma.

    PubMed

    Tamai, Tsutomu; Taniyama, Oki; Oda, Kohei; Kasai, Ai; Ijyuin, Syo; Sakae, Haruka; Onishi, Hiroka; Tabu, Kazuaki; Kumagai, Kotaro; Mawatari, Seiichi; Moriuchi, Akihiro; Uto, Hirofumi; Ido, Akio

    2018-05-01

    We confirmed the clinical utility of a three-dimensional navigation system during transarterial chemoembolization. We evaluated 128 tumors in 91 patients enrolled between May 2015 and August 2016. We evaluated the accuracy of the three-dimensional navigation imaging system for all tumors. We compared the patients who were able to undergo route detection using three-dimensional navigation with previously treated patients who underwent transarterial chemoembolization without using three-dimensional navigation (n = 21). For 38 patients who underwent super-selective microcatheter insertion after a feeding artery was identified by three-dimensional navigation, we confirmed the relationship between the tumors and contrasted liver parenchyma and divided the computed tomography hepatic arteriography findings into four grades. Grade 1: an overlap of > 5 mm, grade 2: an overlap between 0 and 5 mm, grade 3: the borders of the tumor within the liver parenchyma but in contact with the edges, and grade 4: a tumor outside the borders of the liver parenchyma. Using the three-dimensional navigation system, we identified a tumor-feeding artery in 125/128 tumors (97.6%). Furthermore, this system allowed us to significantly reduce the volume of contrast media and the radiation exposure dose in patients undergoing an evaluation. We identified 15 grade 1 tumors (39.5%), 3 grade 2 tumors (7.9%), 11 grade 3 tumors (28.9%), and 9 grade 4 tumors (23.7%) according to our definitions. The three-dimensional navigation is useful not only for patients but also for surgeons who have relatively little experience. © 2017 Journal of Gastroenterology and Hepatology Foundation and John Wiley & Sons Australia, Ltd.

  15. 33 CFR 157.130 - Crude oil washing with more than one grade of crude oil.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... RELATING TO TANK VESSELS CARRYING OIL IN BULK Crude Oil Washing (COW) System on Tank Vessels Design... vessel having a COW system under §§ 157.10(e), 157.10a(a)(2), or 157.10c(b)(2) carries more than one grade of crude oil, the COW system must be capable of washing the cargo tanks with the grades of crude...

  16. [Study on risk assessing indicator system after schistosomiasis transmission interruption in Wuxi City].

    PubMed

    Xiao-Jun, Meng; Sheng-Hua, Zong; Xuan, Zhang; Dong-Lin, Gao; Yan-Hua, Qian; Bing, Lu

    2017-07-27

    To establish a risk assessing indicator system after the transmission interruption of schistosomiasis in Wuxi City, so as to provide evidences for formulating strategies on schistosomiasis control and prevention. A primary risk assessing indicator system was established based on the literature review. Alternative indicators were scored and screened to establish a final indicator system through two rounds of Delphy method and the related normalized weights and combined weights were also calculated. The risk assessing indicator system was established through two rounds of expert consultation including 3 first grade indicators and 15 second grade indicators. Among the first grade indicators, the normalized weights of natural environment, key populations and social environment were 0.370 6, 0.292 9 and 0.336 5, respectively. Among the second grade indicators, the migrant population accounted for the highest combined weight of 0.125 2 compared to domestic animal of 0.037 1. The authority degree among the first grade indicators was between 0.91 and 0.93, while the authority degree among the second grade indicators was between 0.79 and 0.92. The scientific and authoritative risk assessing indicator system after the transmission interruption of schistosomiasis is established, which provides the evidences for risk assessment on schistosomiasis transmission in Wuxi City.

  17. Analysis of tumour-infiltrating lymphocytes reveals two new biologically different subgroups of breast ductal carcinoma in situ.

    PubMed

    Beguinot, Marie; Dauplat, Marie-Melanie; Kwiatkowski, Fabrice; Lebouedec, Guillaume; Tixier, Lucie; Pomel, Christophe; Penault-Llorca, Frederique; Radosevic-Robin, Nina

    2018-02-03

    Tumour-infiltrating lymphocytes (TILs) have been demonstrated to significantly influence prognosis and response to therapy of invasive breast cancer (IBC). Thus, it has been suggested that TIL density or/and immunophenotype could serve as biomarkers for selection of IBC patients for immunotherapy. However, much less is known about significance of TILs in breast ductal carcinoma in situ (DCIS). We retrospectively investigated TIL density and immunophenotype in 96 pure DCIS and 35 microinvasive carcinomas (miCa). TIL density was assessed on H&E-stained breast biopsy sections as the percentage of tumour stromal area occupied by TILs, and classified into 4 grades: 0 (0%-9%), 1 (10-29%), 2 (30-49%) and 3 (50%-100%). TIL immunophenotype was assessed by immunohistochemistry for CD8, CD4, FoxP3, CD38 or CD20. Compared to pure DCIS, miCa contained significantly more cases with TIL density grade 3 (p = 0.028). Concordantly, CD8+, CD4+ and CD38+ cells were more numerous in miCa than in pure DCIS. In the pure DCIS subgroup with TIL density grades 2 and 3, all TIL subpopulations were more numerous than in the pure DCIS with TIL density grades 0 and 1, however the ratio between T-lymphocytes (CD8+ and CD4+) and B-lymphocytes (CD20+) was significantly lower (p = 0.029). On the other side, this ratio was significantly higher in miCa, in comparison with pure DCIS having TIL density grades 2 and 3 (p = 0.017). By cluster analysis of tumour cell pathobiological features we demonstrated similarity between miCa and the pure DCIS with TIL density grades 2 and 3. The only significant difference between those two categories was in the ratio of T- to B-TILs, higher in miCa. Results indicate that TIL density level can distinguish 2 biologically different DCIS subgroups, one of which (DCIS with ≥30% TILs, the TIL-rich DCIS) is like miCa. Similarity of TIL-rich pure DCIS and miCa as well as the role of B-lymphocytes in DCIS invasiveness are worth further investigating with regards to the potential development of immunotherapy-based prevention of DCIS progression.

  18. Selection and evaluation of performance-graded asphalt binders for Virginia.

    DOT National Transportation Integrated Search

    1999-06-01

    This study recommended performance-graded (PG) binders to be used in hot-mix asphalt in Virginia. Ten conventional viscosity-graded asphalt cements, representing the asphalt typically available in Virginia, were graded under the PG system to develop ...

  19. Potential means of cost reduction in grade crossing automatic gate systems. volume II : improved gate arm concepts for railroad/highway grade crossings gate systems

    DOT National Transportation Integrated Search

    1977-02-28

    This report, Volume II of a two-volume study, examines the potential for reduction of the cost of installing and maintaining automatic gates at railroad-highway grade crossings. It includes a review of current practices, equipment, and standards; con...

  20. Potential means of cost reduction in grade crossing automatic gate systems. volume I : overview and low cost railroad/highway grade crossing gate systems

    DOT National Transportation Integrated Search

    1977-02-28

    This report, Volume I of a two-volume study, examines the potential for reduction of the cost of installing and maintaining automatic gates at railroad-highway grade crossings. It comprises a general overview; a review of current practices, equipment...

  1. Gearing up for Fast Grading and Reporting

    ERIC Educational Resources Information Center

    O'Connor, Ken; Jung, Lee Ann; Reeves, Douglas

    2018-01-01

    The authors posit that the traditional grading system involving points and percentages is not the best way to prepare students to be the self-directed, independent learners they need to be. A better system would produce grades that are FAST (fair, accurate, specific, timely). To bring about these changes, school leaders need not create full…

  2. 7 CFR 52.1003 - Grades of dates.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... PROCESSED FRUITS AND VEGETABLES, PROCESSED PRODUCTS THEREOF, AND CERTAIN OTHER PROCESSED FOOD PRODUCTS 1... the scoring system outlined in this subpart. (b) U.S. Grade B or U.S. Choice is the quality of whole... the scoring system outlined in this subpart. (c) U.S. Grade B (Dry) or U.S. Choice (Dry) is the...

  3. Inter-rater reliability of postnatal ultrasound interpretation in infants with congenital hydronephrosis.

    PubMed

    Vemulakonda, V M; Wilcox, D T; Torok, M R; Hou, A; Campbell, J B; Kempe, A

    2015-09-01

    The most common measurements of hydronephrosis are the anterior-posterior (AP) diameter and the Society for Fetal Urology (SFU) grading systems. To date, the inter-rater reliability (IRR) of these measures has not been compared in the postnatal period. The objectives of this study were to compare the IRR of the AP diameter and the SFU grading system in infants and to determine whether ultrasound findings other than pelvicalyceal dilation are associated with higher SFU grades. Initial postnatal ultrasounds of infants seen from February 1, 2011, to January 31, 2012, with a primary diagnosis of congenital hydronephrosis were included for review. Ultrasound images were de-identified and reviewed by four pediatric urologists. IRR was calculated using the intraclass correlation (ICC) measure. A paired t test was used to compare ICCs. Associations between SFU grade and other ultrasound findings were tested using Chi-square or Fisher's exact tests. A total of 112 kidneys in 56 patients were reviewed. IRR of the SFU grading system was high (right kidney ICC = 0.83, left kidney ICC = 0.85); however, IRR of AP diameter measurement was higher (right kidney ICC = 00.97, left kidney ICC = 0.98; p < 0.001). Renal asymmetry (p < 0.001), echogenicity (p < 0.001), and parenchymal thinning (p < 0.001) were significantly associated with SFU grade 4 hydronephrosis on bivariable and multivariable analysis. The SFU grading system is associated with excellent IRR, although the AP diameter appears to have higher IRR. Physicians may consider ultrasound findings that are not explicitly included in the SFU system when assigning hydronephrosis grade, which may lead to variability in use of this classification system.

  4. TREEGRAD: a grading program for eastern hardwoods

    Treesearch

    J.W. Stringer; D.W. Cremeans

    1991-01-01

    Assigning tree grades to eastern hardwoods is often a difficult task for neophyte graders. Recently several "dichotomous keys" have been developed for training graders in the USFS hardwood tree grading system. TREEGRAD uses the Tree Grading Algorithm (TGA) for determining grades from defect location data and is designed to be used as a teaching aid.

  5. What's in a Grade? Grading Policies and Practices in Principles of Economics

    ERIC Educational Resources Information Center

    Walstad, William B.; Miller, Laurie A.

    2016-01-01

    Survey results from a national sample of economics instructors describe the grading policies and practices in principles of economics courses. The survey results provide insights about absolute and relative grading systems used by instructors, the course components and their weights that determine grades, and the type of assessment items used for…

  6. T cell infiltrate and outcome following resection of intermediate-grade primary neuroendocrine tumours and liver metastases.

    PubMed

    Katz, Steven C; Donkor, Charan; Glasgow, Kristen; Pillarisetty, Venu G; Gönen, Mithat; Espat, N Joseph; Klimstra, David S; D'Angelica, Michael I; Allen, Peter J; Jarnagin, William; Dematteo, Ronald P; Brennan, Murray F; Tang, Laura H

    2010-12-01

    Tumour-infiltrating lymphocytes (TILs) have been shown to predict survival in numerous malignancies. The importance of TILs in primary pancreatic neuroendocrine tumours (NETs) and NET liver metastases (NETLMs) has not been defined. We identified 87 patients with NETs and 39 with NETLMs who had undergone resection. Immunohistochemistry was performed to determine TIL counts. Recurrence-free survival (RFS) and overall survival (OS) were determined using the log-rank test. The median follow-up time was 62 months in NET patients and 48 months in NETLM patients. Vascular invasion and histologic grade were the only independent predictors of outcome for NETs and NETLMs, respectively. Analysis of intermediate-grade NETs indicated that a dense T cell (CD3+) infiltrate was associated with a median RFS of 128 months compared with 61 months for those with low levels of intratumoral T cells (P= 0.05, univariate analysis). Examination of NETLMs revealed that a low level of infiltrating regulatory T cells (Treg, FoxP3+) was a predictor of prolonged survival (P < 0.01, univariate analysis). A robust T cell infiltrate is associated with improved RFS following resection of intermediate-grade NETs, whereas the presence of more Treg correlated with shorter OS after treatment of NETLMs. Further study of the immune response to intermediate-grade NETs and NETLMs is warranted.

  7. The Relation between 1st Grade Grey Matter Volume and 2nd Grade Math Competence

    PubMed Central

    Price, Gavin R.; Wilkey, Eric D.; Yeo, Darren J.; Cutting, Laurie E.

    2015-01-01

    Mathematical and numerical competence is a critical foundation for individual success in modern society yet the neurobiological sources of individual differences in math competence are poorly understood. Neuroimaging research over the last decade suggests that neural mechanisms in the parietal lobe, particularly the intraparietal sulcus (IPS) are structurally aberrant in individuals with mathematical learning disabilities. However, whether those same brain regions underlie individual differences in math performance across the full range of math abilities is unknown. Furthermore, previous studies have been exclusively cross-sectional, making it unclear whether variations in the structure of the IPS are caused by or consequences of the development of math skills. The present study investigates the relation between grey matter volume across the whole brain and math competence longitudinally in a representative sample of 50 elementary school children. Results show that grey matter volume in the left IPS at the end of 1st grade relates to math competence a year later at the end of 2nd grade. Grey matter volume in this region did not change over that year, and was still correlated with math competence at the end of 2nd grade. These findings support the hypothesis that the IPS and its associated functions represent a critical foundation for the acquisition of mathematical competence. PMID:26334946

  8. Technological Innovation in Grade Crossing Protective Systems

    DOT National Transportation Integrated Search

    1971-06-01

    The constraints on innovative grade crossing protective systems are delineated and guidelines for development indicated. Inventory data has been arranged to permit an estimate of the classes of systems needed, the allowable costs, and contribution of...

  9. Readmission after treatment of Grade 3 and 4 renal injuries at a Level I trauma center: Statewide assessment using the Comprehensive Hospital Abstract Reporting System.

    PubMed

    Winters, Brian; Wessells, Hunter; Voelzke, Bryan B

    2016-03-01

    One criticism of the existing renal trauma research is the limited outpatient follow-up after index hospitalization. We assessed readmission rates following treatment for American Association for the Surgery of Trauma (AAST) Grade 3 and 4 renal injury using the Comprehensive Hospital Abstract Reporting System (CHARS). We evaluated all patients with AAST Grade 3 and 4 renal injuries admitted to Harborview Medical Center (HMC) between 1998 and 2010, the only Level 1 trauma center in Washington state. Grade 4 renal injuries were stratified by collecting system laceration (CSL) or segmental vascular injury. Data were abstracted from the CHARS database for readmissions to any Washington state hospital within 6 months of renal injury. Clinical variables, diagnoses, and procedures were queried based on DRG International Classification of Diseases-9th Rev. codes. A total of 477 Grade 3 and 159 Grade 4 renal injuries were initially treated at HMC. On admission, 111 patients required intervention: 75 (16%) of 477 Grade 3 and 36 (23%) of 159 Grade 4 injuries. Within 6 months of index hospitalization, 86 (18%) of 477 Grade 3 and 38 (24%) of 159 Grade 4 patients were readmitted to any Washington state hospital. Eighty percent of Grade 3 injuries and 66% of Grade 4 injuries returned to HMC compared with secondary hospitals (p = 0.08). At readmission, 19 (22%) of 86 Grade 3 and 16 (42%) of 38 Grade 4 injuries had a urologic diagnosis. Subsequent procedural intervention was required on readmission in 6 (7%) of 86 Grade 3 and 5 (13%) of 38 Grade 4 renal injuries (all CSL injuries). A subset of patients treated for Grade 3 and 4 renal trauma will be readmitted for further management. While urologic diagnoses and additional procedures may be low overall, readmission to outside hospitals may preclude accurate determination of renal trauma outcomes. Based on these data, patients with Grade 4 CSL injuries seem to be at the highest risk for readmission and to require a subsequent urologic procedure. Prognostic/epidemiologic study, level III.

  10. Performance evaluation of image-intensifier-TV fluoroscopy systems

    NASA Astrophysics Data System (ADS)

    van der Putten, Wilhelm J.; Bouley, Shawn

    1995-05-01

    Through use of a computer model and an aluminum low contrast phantom developed in-house, a method has been developed which is able to grade the imaging performance of fluoroscopy systems through use of a variable, K. This parameter was derived from Rose's model of image perception and is here used as a figure of merit to grade fluoroscopy systems. From Rose's model for an ideal system, a typical value of K for the perception of low contrast details should be between 3 and 7, assuming threshold vision by human observers. Thus, various fluoroscopy systems are graded with different values of K, with a lower value of K indicating better imaging performance of the system. A series of fluoroscopy systems have been graded where the best system produces a value in the low teens, while the poorest systems produce a value in the low twenties. Correlation with conventional image quality measurements is good and the method has the potential for automated assessment of image quality.

  11. Subchondral bone histology and grading in osteoarthritis

    PubMed Central

    Aho, Olli-Matti; Finnilä, Mikko; Thevenot, Jerome; Saarakkala, Simo; Lehenkari, Petri

    2017-01-01

    Objective Osteoarthritis (OA) has often regarded as a disease of articular cartilage only. New evidence has shifted the paradigm towards a system biology approach, where also the surrounding tissue, especially bone is studied more vigorously. However, the histological features of subchondral bone are only poorly characterized in current histological grading scales of OA. The aim of this study is to specifically characterize histological changes occurring in subchondral bone at different stages of OA and propose a simple grading system for them. Design 20 patients undergoing total knee replacement surgery were randomly selected for the study and series of osteochondral samples were harvested from the tibial plateaus for histological analysis. Cartilage degeneration was assessed using the standardized OARSI grading system, while a novel four-stage grading system was developed to illustrate the changes in subchondral bone. Subchondral bone histology was further quantitatively analyzed by measuring the thickness of uncalcified and calcified cartilage as well as subchondral bone plate. Furthermore, internal structure of calcified cartilage-bone interface was characterized utilizing local binary patterns (LBP) based method. Results The histological appearance of subchondral bone changed drastically in correlation with the OARSI grading of cartilage degeneration. As the cartilage layer thickness decreases the subchondral plate thickness and disorientation, as measured with LBP, increases. Calcified cartilage thickness was highest in samples with moderate OA. Conclusion The proposed grading system for subchondral bone has significant relationship with the corresponding OARSI grading for cartilage. Our results suggest that subchondral bone remodeling is a fundamental factor already in early stages of cartilage degeneration. PMID:28319157

  12. Mapping the magnonic landscape in patterned magnetic structures

    NASA Astrophysics Data System (ADS)

    Davies, C. S.; Poimanov, V. D.; Kruglyak, V. V.

    2017-09-01

    We report the development of a hybrid numerical/analytical model capable of mapping the spatially varying distributions of the local ferromagnetic resonance (FMR) frequency and dynamic magnetic susceptibility in a wide class of patterned and compositionally modulated magnetic structures. Starting from the numerically simulated static micromagnetic state, the magnetization is deliberately deflected orthogonally to its equilibrium orientation, and the magnetic fields generated in response to this deflection are evaluated using micromagnetic software. This allows us to calculate the elements of the effective demagnetizing tensor, which are then used within a linear analytical formalism to map the local FMR frequency and dynamic magnetic susceptibility. To illustrate the typical results that one can obtain using this model, we analyze three micromagnetic systems boasting nonuniformity in either one or two dimensions, and successfully explain the spin-wave emission observed in each case, demonstrating the ubiquitous nature of the Schlömann excitation mechanism underpinning the observations. Finally, the developed model of local FMR frequency can be used to explain how spin waves could be confined and steered using magnetic nonuniformities of various origins, rendering it a powerful tool for the mapping of the graded magnonic index in magnonics.

  13. Grading NASA's Solar System Exploration Program: A Midterm Report

    NASA Technical Reports Server (NTRS)

    2008-01-01

    The Committee on Assessing the Solar System Exploration Program has reviewed NASA's progress to date in implementing the recommendations made in the National Research Council's (NRC's) solar system exploration decadal survey covering the period 2003-2013, New Frontiers in the Solar System, and in its Mars Architecture report, Assessment of NASA s Mars Architecture 2007-2016. The committee assessed NASA's progress with respect to each individual recommendation in these two reports, assigning an academic-style grade, explaining the rationale for the grade and trend, and offering recommendations for improvement. The committee generally sought to develop recommendations in cases where it determined that the grade, the trend, or both were worrisome and that the achievement of a decadal survey recommendation would require some kind of corrective action on NASA's part. This usually meant that the committee sought to offer a recommendation when the grade was a "C" or lower. However, the committee did offer recommendations in connection with some higher grades when it believed that minor corrective action was possible and desirable. More importantly, the committee did not offer recommendations for some of the activities given lower grades, particularly in the enabling technologies area (Chapter 6), because the committee determined that only the restoration of funding and the development of a strategic technology development program would solve these problems.

  14. Agreement between the Facial Nerve Grading System 2.0 and the House-Brackmann Grading System in Patients with Bell Palsy.

    PubMed

    Lee, Ho Yun; Park, Moon Suh; Byun, Jae Yong; Chung, Ji Hyun; Na, Se Young; Yeo, Seung Geun

    2013-09-01

    We have analyzed the correlation between the House-Brackmann (HB) scale and Facial Nerve Grading System 2.0 (FNGS 2.0) in patients with Bell palsy, and evaluated the usefulness of the new grading system. Sixty patients diagnosed with Bell palsy from May 2009 to December 2010 were evaluated using the HB scale and FNGS 2.0 scale during their initial visit, and after 3 and 6 weeks and 3 months. The overall intraclass correlation coefficient (ICC) was 0.908 (P=0.000) and the Spearman correlation coefficient (SCC) was 0.912 (P<0.05). ICC and SCC displayed differences over time, being 0.604 and 0.626, respectively, at first visit; 0.834 and 0.843, respectively, after 3 weeks; 0.844 and 0.848, respectively, after 6 weeks; and 0.808 and 0.793, respectively, after 3 months. There was a significant difference in full recovery, depending on the scale used (HB, P=0.000; FNGS 2.0, P<0.05). The exact agreements between regional assessment and FNGS 2.0 for the mouth, eyes, and brow were 72%, 63%, and 52%, respectively. FNGS 2.0 shows moderate agreement with HB grading. Regional assessment, rather than HB grading, yields stricter evaluation, resulting in better prognosis and determination of grade.

  15. Teacher's Guide to the Internet

    ERIC Educational Resources Information Center

    Blaylock, Jenny L.

    2005-01-01

    This paper is designed for teachers of students in grades Pre-K through 12 and will introduce them to the numerous curriculum resources on the Internet. More often today supplements to course curriculum can be found on any text book company web site. Even more important is the amount of curriculum resources available for free on the Internet.…

  16. Tutoring Programs for Struggling Readers: The America Reads Challenge. Rutgers Invitational Symposia on Education.

    ERIC Educational Resources Information Center

    Morrow, Lesley Mandel, Ed.; Woo, Deborah Gee, Ed.

    As a result of the America Reads Challenge Act of 1997, numerous tutoring programs have been established to help ensure that every child reads independently by the end of third grade. This book describes exemplary America Reads programs across the country as well as other effective early literacy interventions, including Reading Recovery, the…

  17. School Students' Food Services in Primorskii Krai: Reality and Prospects

    ERIC Educational Resources Information Center

    Shemetova, E. V.; Shchenikova, N. V.

    2009-01-01

    In the past ten years, children's health has become qualitatively worse. According to the data from numerous studies in Russia, only 10 percent of the upper-grade students in secondary school can be considered healthy. At the same time, half the students have morphofunctional impairments, and 40 percent suffer from chronic pathology. In the past…

  18. A Comparison of the Intellectual Abilities of Good and Poor Problem Solvers: An Exploratory Study.

    ERIC Educational Resources Information Center

    Meyer, Ruth Ann

    This study examined a selected sample of fourth-grade students who had been previously identified as good or poor problem solvers. The pupils were compared on variables considered as "reference tests" for Verbal, Induction, Numerical, Word Fluency, Memory, Spatial Visualization, and Perceptual Speed abilities. The data were compiled to…

  19. Probing the Natural World, Level III, Student Guide: Investigating Variation. Intermediate Science Curriculum Study.

    ERIC Educational Resources Information Center

    Bonar, John R., Ed.; Hathway, James A., Ed.

    This is the student's text of one unit of the Intermediate Science Curriculum Study (ISCS) for level III students (grade 9). This unit focuses on diversity in human populations, measurement, and data collection. Numerous activities are given and optional excursions encourage students to pursue a topic in greater depth. Data tables within the…

  20. The Impact of Course Length on Online Numeric-Based Course Grades

    ERIC Educational Resources Information Center

    Mensch, Scott

    2013-01-01

    When offering online classes, it is necessary to ensure that all course material and objectives will be covered and learners will be successful in the course. This becomes especially important when the same class material and objectives are offered in a three-, five-, and fourteen-week format. This paper outlines the difficulty of delivering…

  1. Improving Access to Elementary School Social Studies Instruction: Strategies to Support Students with Learning Disabilities

    ERIC Educational Resources Information Center

    Ciullo, Stephen

    2015-01-01

    Social studies instruction in upper elementary school (Grades 3-5) is important for building foundational content knowledge to equip students for the secondary school curriculum. Due to numerous school initiatives and demands on the time of teachers, social studies instruction can play second fiddle to reading and mathematics instruction, which…

  2. Number Sense Routines: Building Numerical Literacy Every Day in Grades K-3

    ERIC Educational Resources Information Center

    Shumway, Jessica

    2011-01-01

    Just as athletes stretch their muscles before every game and musicians play scales to keep their technique in tune, mathematical thinkers and problem solvers can benefit from daily warm-up exercises. Jessica Shumway has developed a series of routines designed to help young students internalize and deepen their facility with numbers. The daily use…

  3. Numerical Distance Effect in Developmental Dyscalculia

    ERIC Educational Resources Information Center

    Ashkenazi, Sarit; Mark-Zigdon, Nitza; Henik, Avishai

    2009-01-01

    Children in third and fourth grades suffering from developmental dyscalculia (DD) and typically developing children were asked to compare numbers to a standard. In two separate blocks, they were asked to compare a number between 1 and 9 to 5, or a two-digit number between 10 and 99 to 55. In the single-digit comparisons, DD children were…

  4. Track Picture Book. Elementary Science Study.

    ERIC Educational Resources Information Center

    Webster, David; And Others

    This picture book was designed to be used with an Elementary Science Study unit that provides opportunities for students in grades 4-6 to study animal tracks. Shown within this book are numerous examples of tracks, including those of tires, human beings, animal tracks, and others in various media, such as snow, sand, mud, dust, and cement. (CS)

  5. The Relationship of Life Events to Academic Performance in College Students.

    ERIC Educational Resources Information Center

    Knapp, Samuel

    Numerous studies have shown a correlation between life events and physical health, mental health, and behavioral measures such as impaired grade point average. Most of these studies have measured stressfulness by summing the total number of events experienced in a given time period. However, Vinokur and Selzer have shown that the amount of…

  6. Modelling of Factors Influencing Gender Difference in Mathematics Achievement Using TIMSS 2011 Data for Singaporean Eighth Grade Students

    ERIC Educational Resources Information Center

    Yoo, Yang Seok

    2018-01-01

    Numerous studies have attributed gender difference in mathematics achievement to various sociocultural influences. Singapore is a country of higher gender equality as represented in the Global Gender Gap Index and Singaporean girls perform as well or higher than boys in international mathematics assessments. This study develops a conceptual model…

  7. International collaborative studies on potency assays of diphtheria and tetanus toxoids.

    PubMed

    Van Ramshorst, J D; Sundaresan, T K; Outschoorn, A S

    1972-01-01

    Collaborative studies showed that relative potency assays for a particular type of diphtheria toxoid (adsorbed) and for tetanus toxoid (plain and adsorbed) gave very similar results, whether the assays were carried out by toxin challenge or by antitoxin titration after immunization of experimental animals with graded doses of toxoid. The same numerical results were obtained with a scoring system as with a system based on survivals only. Although skin tests were used on a very limited scale in these studies, it seems likely that they could replace lethal tests for the diphtheria challenge assays.For both tetanus and diphtheria, the adsorbed toxoid gave a higher relative potency when combined with other antigens than as a single toxoid. Both mice and guinea-pigs were used for the lethal challenge test of adsorbed tetanus toxoid. For the single tetanus toxoid the results were the same, but for the combined toxoid (DPT vaccine) the mouse assay results were about twice those of guinea-pig assays.

  8. International collaborative studies on potency assays of diphtheria and tetanus toxoids

    PubMed Central

    van Ramshorst, J. D.; Sundaresan, T. K.; Outschoorn, A. S.

    1972-01-01

    Collaborative studies showed that relative potency assays for a particular type of diphtheria toxoid (adsorbed) and for tetanus toxoid (plain and adsorbed) gave very similar results, whether the assays were carried out by toxin challenge or by antitoxin titration after immunization of experimental animals with graded doses of toxoid. The same numerical results were obtained with a scoring system as with a system based on survivals only. Although skin tests were used on a very limited scale in these studies, it seems likely that they could replace lethal tests for the diphtheria challenge assays. For both tetanus and diphtheria, the adsorbed toxoid gave a higher relative potency when combined with other antigens than as a single toxoid. Both mice and guinea-pigs were used for the lethal challenge test of adsorbed tetanus toxoid. For the single tetanus toxoid the results were the same, but for the combined toxoid (DPT vaccine) the mouse assay results were about twice those of guinea-pig assays. PMID:4537488

  9. Fuxianhuiid ventral nerve cord and early nervous system evolution in Panarthropoda

    PubMed Central

    Yang, Jie; Ortega-Hernández, Javier; Butterfield, Nicholas J.; Liu, Yu; Boyan, George S.; Hou, Jin-bo; Lan, Tian; Zhang, Xi-guang

    2016-01-01

    Panarthropods are typified by disparate grades of neurological organization reflecting a complex evolutionary history. The fossil record offers a unique opportunity to reconstruct early character evolution of the nervous system via exceptional preservation in extinct representatives. Here we describe the neurological architecture of the ventral nerve cord (VNC) in the upper-stem group euarthropod Chengjiangocaris kunmingensis from the early Cambrian Xiaoshiba Lagerstätte (South China). The VNC of C. kunmingensis comprises a homonymous series of condensed ganglia that extend throughout the body, each associated with a pair of biramous limbs. Submillimetric preservation reveals numerous segmental and intersegmental nerve roots emerging from both sides of the VNC, which correspond topologically to the peripheral nerves of extant Priapulida and Onychophora. The fuxianhuiid VNC indicates that ancestral neurological features of Ecdysozoa persisted into derived members of stem-group Euarthropoda but were later lost in crown-group representatives. These findings illuminate the VNC ground pattern in Panarthropoda and suggest the independent secondary loss of cycloneuralian-like neurological characters in Tardigrada and Euarthropoda. PMID:26933218

  10. Fuxianhuiid ventral nerve cord and early nervous system evolution in Panarthropoda.

    PubMed

    Yang, Jie; Ortega-Hernández, Javier; Butterfield, Nicholas J; Liu, Yu; Boyan, George S; Hou, Jin-Bo; Lan, Tian; Zhang, Xi-Guang

    2016-03-15

    Panarthropods are typified by disparate grades of neurological organization reflecting a complex evolutionary history. The fossil record offers a unique opportunity to reconstruct early character evolution of the nervous system via exceptional preservation in extinct representatives. Here we describe the neurological architecture of the ventral nerve cord (VNC) in the upper-stem group euarthropod Chengjiangocaris kunmingensis from the early Cambrian Xiaoshiba Lagerstätte (South China). The VNC of C. kunmingensis comprises a homonymous series of condensed ganglia that extend throughout the body, each associated with a pair of biramous limbs. Submillimetric preservation reveals numerous segmental and intersegmental nerve roots emerging from both sides of the VNC, which correspond topologically to the peripheral nerves of extant Priapulida and Onychophora. The fuxianhuiid VNC indicates that ancestral neurological features of Ecdysozoa persisted into derived members of stem-group Euarthropoda but were later lost in crown-group representatives. These findings illuminate the VNC ground pattern in Panarthropoda and suggest the independent secondary loss of cycloneuralian-like neurological characters in Tardigrada and Euarthropoda.

  11. Analytical and numerical study of electroosmotic slip flows of fractional second grade fluids

    NASA Astrophysics Data System (ADS)

    Wang, Xiaoping; Qi, Haitao; Yu, Bo; Xiong, Zhen; Xu, Huanying

    2017-09-01

    This work investigates the unsteady electroosmotic slip flow of viscoelastic fluid through a parallel plate micro-channel under combined influence of electroosmotic and pressure gradient forcings with asymmetric zeta potentials at the walls. The generalized second grade fluid with fractional derivative was used for the constitutive equation. The Navier slip model with different slip coefficients at both walls was also considered. By employing the Debye-Hückel linearization and the Laplace and sin-cos-Fourier transforms, the analytical solutions for the velocity distribution are derived. And the finite difference method for this problem was also given. Finally, the influence of pertinent parameters on the generation of flow is presented graphically.

  12. Effect of gradient dielectric coefficient in a functionally graded material (FGM) substrate on the propagation behavior of love waves in an FGM-piezoelectric layered structure.

    PubMed

    Cao, Xiaoshan; Shi, Junping; Jin, Feng

    2012-06-01

    The propagation behavior of Love waves in a layered structure that includes a functionally graded material (FGM) substrate carrying a piezoelectric thin film is investigated. Analytical solutions are obtained for both constant and gradient dielectric coefficients in the FGM substrate. Numerical results show that the gradient dielectric coefficient decreases phase velocity in any mode, and the electromechanical coupling factor significantly increases in the first- and secondorder modes. In some modes, the difference in Love waves' phase velocity between these two types of structure might be more than 1%, resulting in significant differences in frequency of the surface acoustic wave devices.

  13. Oncogenic role of fibroblast growth factor receptor 3 in tumorigenesis of urinary bladder cancer.

    PubMed

    Pandith, Arshad A; Shah, Zafar A; Siddiqi, Mushtaq A

    2013-05-01

    Bladder cancer is the second most common genitourinary tumor and constitutes a very heterogeneous disease. Molecular and pathologic studies suggest that low-grade noninvasive and high-grade invasive urothelial cell carcinoma (UCC) arise via distinct pathways. Low-grade noninvasive UCC represent the majority of tumors at presentation. A high proportion of patients with low-grade UCC develop recurrences but usually with no progression to invasive disease. At presentation, a majority of the bladder tumors (70%-80%) are low-grade noninvasive (pTa). Several genetic changes may occur in bladder cancer, but activating mutations in the fibroblast growth factor receptor 3 (FGFR3) genes are the most common and most specific genetic abnormality in bladder cancer. Interestingly, these mutations are associated with bladder tumors of low stage and grade, which makes the FGFR3 mutation the first marker that can be used for diagnosis of noninvasive bladder tumors. Since the first report of FGFR3 involvement in bladder tumors, numerous studies have been conducted to understand its function and thereby confirm the oncogenic role of this receptor particularly in noninvasive groups. Efforts are on to exploit this receptor as a therapeutic target, which holds much promise in the treatment of bladder cancer, particularly low-grade noninvasive tumors. Further studies need to explore the potential use of FGFR3 mutations in bladder cancer diagnosis, prognosis, and in surveillance of patients with bladder cancer. This review focuses on the role of FGFR3 in bladder tumors in the backdrop of various studies published. Copyright © 2013 Elsevier Inc. All rights reserved.

  14. Longitudinal prediction and concurrent functioning of adolescent girls demonstrating various profiles of dating violence and victimization.

    PubMed

    Chiodo, Debbie; Crooks, Claire V; Wolfe, David A; McIsaac, Caroline; Hughes, Ray; Jaffe, Peter G

    2012-08-01

    Adolescent girls are involved in physical dating violence as both perpetrators and victims, and there are negative consequences associated with each of these behaviors. This article used a prospective design with 519 girls dating in grade 9 to predict profiles of dating violence in grade 11 based on relationships with families of origin (child maltreatment experiences, harsh parenting), and peers (harassment, delinquency, relational aggression). In addition, dating violence profiles were compared on numerous indices of adjustment (school connectedness, grades, self-efficacy and community connectedness) and maladjustment (suicide attempts, distress, delinquency, sexual behavior) for descriptive purposes. The most common profile was no dating violence (n = 367) followed by mutual violence (n = 81). Smaller numbers of girls reported victimization or perpetration only (ns = 39 and 32, respectively). Predicting grade 11 dating violence profile membership from grade 9 relationships was limited, although delinquency, parental rejection, and sexual harassment perpetration predicted membership to the mutually violent group, and delinquency predicted the perpetrator-only group. Compared to the non-violent group, the mutually violent girls in grade 11 had lower grades, poorer self-efficacy, and lower school connectedness and community involvement. Furthermore, they had higher rates of peer aggression and delinquency, were less likely to use condoms and were much more likely to have considered suicide. There were fewer differences among the profiles for girls involved with dating violence. In addition, the victims-only group reported higher rates of sexual intercourse, comparable to the mutually violent group and those involved in nonviolent relationships. Implications for prevention and intervention are highlighted.

  15. 49 CFR 234.303 - Emergency notification systems for telephonic reporting of unsafe conditions at highway-rail and...

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... reporting of unsafe conditions at highway-rail and pathway grade crossings. 234.303 Section 234.303... at Highway-Rail and Pathway Grade Crossings § 234.303 Emergency notification systems for telephonic reporting of unsafe conditions at highway-rail and pathway grade crossings. (a) Duty of dispatching railroad...

  16. 49 CFR 234.303 - Emergency notification systems for telephonic reporting of unsafe conditions at highway-rail and...

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... reporting of unsafe conditions at highway-rail and pathway grade crossings. 234.303 Section 234.303... at Highway-Rail and Pathway Grade Crossings § 234.303 Emergency notification systems for telephonic reporting of unsafe conditions at highway-rail and pathway grade crossings. (a) Duty of dispatching railroad...

  17. 49 CFR 234.303 - Emergency notification systems for telephonic reporting of unsafe conditions at highway-rail and...

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... reporting of unsafe conditions at highway-rail and pathway grade crossings. 234.303 Section 234.303... at Highway-Rail and Pathway Grade Crossings § 234.303 Emergency notification systems for telephonic reporting of unsafe conditions at highway-rail and pathway grade crossings. (a) Duty of dispatching railroad...

  18. Plus and Minus Grading Options: Toward Accurate Student Performance Evaluations.

    ERIC Educational Resources Information Center

    California Community Colleges, Sacramento. Academic Senate.

    Although both the University of California and the California State University systems have the option to use plus or minus grades in student evaluations, the Board of Governors of the California Community Colleges (CCC) does not allow the use of such a grading system. Since 1985, the CCC's Academic Senate has lobbied the Board to allow local…

  19. Economics of Grading and Sorting Pallet Parts

    Treesearch

    Daniel L. Schmoldt; John A. McLeod; Philip A. Araman

    1993-01-01

    Before trying to develop an automated inspection system for pallet part grading we analyzed the economics of such a system. Our results suggest that higher quality pallets produced by grading and sorting pallet parts would be attractive to both manufacturers and their customers, who would have to pay increased prices for higher quality pallets. Reductions in cost-per-...

  20. Resource Allocation Patterns and Student Achievement

    ERIC Educational Resources Information Center

    James, Lori; Pate, James; Leech, Donald; Martin, Ellice; Brockmeier, Lantry; Dees, Elizabeth

    2011-01-01

    This quantitative research study was designed to examine the relationship between system resource allocation patterns and student achievement, as measured by eighth grade Criterion-Referenced Competency Test (CRCT) mathematics, eighth grade CRCT reading, eleventh grade Georgia High School Graduation Test (GHSGT) mathematics, eleventh grade and…

  1. Evaluating Sermons: The Function of Grades in Teaching Preaching

    ERIC Educational Resources Information Center

    Helsel, Carolyn Browning

    2017-01-01

    What are grades doing in a homiletics classroom? This article traces the function of grades through the broader history of the educational system in the United States and then makes suggestions for how grades can be used more effectively in teaching preaching. Beginning in the nineteenth century, teachers used grades to rank and motivate students,…

  2. Measuring Anatomic Severity in Pediatric Appendicitis: Validation of the American Association for the Surgery of Trauma Appendicitis Severity Grade.

    PubMed

    Hernandez, Matthew C; Polites, Stephanie F; Aho, Johnathon M; Haddad, Nadeem N; Kong, Victor Y; Saleem, Humza; Bruce, John L; Laing, Grant L; Clarke, Damian L; Zielinski, Martin D

    2018-01-01

    To assess whether the American Association for the Surgery of Trauma (AAST) grading system accurately corresponds with appendicitis outcomes in a US pediatric population. This single-institution retrospective review included patients <18 years of age (n = 331) who underwent appendectomy for acute appendicitis from 2008 to 2012. Demographic, clinical, procedural, and follow-up data (primary outcome was measured as Clavien-Dindo grade of complication severity) were abstracted. AAST grades were generated based on intraoperative findings. Summary, univariate, and multivariable regression analyses were performed to compare AAST grade and outcomes. Overall, 331 patients (46% female) were identified with a median age of 12 (IQR, 8-15) years. Appendectomy was laparoscopic in 90% and open in 10%. AAST grades included: Normal (n = 13, 4%), I (n = 152, 46%), II (n = 90, 27%), III (n = 43, 13%), IV (n = 24 7.3%), and V (n = 9 2.7%). Increased AAST grade was associated with increased Clavien-Dindo severity, P =.001. The overall complication rate was 13.6% and was comprised by superficial surgical site infection (n = 13, 3.9%), organ space infection (n = 15, 4.5%), and readmission (n = 17, 5.1%). Median duration of stay increased with AAST grade (P < .0001). Nominal logistic regression identified the following as predictors of any complication (P < .05): AAST grade and febrile temperature at admission. The AAST appendicitis grading system is valid in a single-institution pediatric population. Increasing AAST grade incrementally corresponds with patient outcomes including increased risk of complications and severity of complications. Determination of the generalizability of this grading system is required. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. An Investigation of the Generalizability of Medical School Grades.

    PubMed

    Kreiter, Clarence D; Ferguson, Kristi J

    2016-01-01

    Construct/Background: Medical school grades are currently unstandardized, and their level of reliability is unknown. This means their usefulness for reporting on student achievement is also not well documented. This study investigates grade reliability within 1 medical school. Generalizability analyses are conducted on grades awarded. Grades from didactic and clerkship-based courses were treated as 2 levels of a fixed facet within a univariate mixed model. Grades from within the 2 levels (didactic and clerkship) were also entered in a multivariate generalizability study. Grades from didactic courses were shown to produce a highly reliable mean score (G = .79) when averaged over as few as 5 courses. Although the universe score correlation between didactic and clerkship courses was high (r = .80), the clerkship courses required almost twice as many grades to reach a comparable level of reliability. When grades were converted to a Pass/Fail metric, almost all information contained in the grades was lost. Although it has been suggested that the imprecision of medical school grades precludes their use as a reliable indicator of student achievement, these results suggest otherwise. While it is true that a Pass/Fail system of grading provides very little information about a student's level of performance, a multi-tiered grading system was shown to be a highly reliable indicator of student achievement within the medical school. Although grades awarded during the first 2 didactic years appear to be more reliable than clerkship grades, both yield useful information about student performance within the medical college.

  4. Online evaluation of a commercial video image analysis system (Computer Vision System) to predict beef carcass red meat yield and for augmenting the assignment of USDA yield grades. United States Department of Agriculture.

    PubMed

    Cannell, R C; Belk, K E; Tatum, J D; Wise, J W; Chapman, P L; Scanga, J A; Smith, G C

    2002-05-01

    Objective quantification of differences in wholesale cut yields of beef carcasses at plant chain speeds is important for the application of value-based marketing. This study was conducted to evaluate the ability of a commercial video image analysis system, the Computer Vision System (CVS) to 1) predict commercially fabricated beef subprimal yield and 2) augment USDA yield grading, in order to improve accuracy of grade assessment. The CVS was evaluated as a fully installed production system, operating on a full-time basis at chain speeds. Steer and heifer carcasses (n = 296) were evaluated using CVS, as well as by USDA expert and online graders, before the fabrication of carcasses into industry-standard subprimal cuts. Expert yield grade (YG), online YG, CVS estimated carcass yield, and CVS measured ribeye area in conjunction with expert grader estimates of the remaining YG factors (adjusted fat thickness, percentage of kidney-pelvic-heart fat, hot carcass weight) accounted for 67, 39, 64, and 65% of the observed variation in fabricated yields of closely trimmed subprimals. The dual component CVS predicted wholesale cut yields more accurately than current online yield grading, and, in an augmentation system, CVS ribeye measurement replaced estimated ribeye area in determination of USDA yield grade, and the accuracy of cutability prediction was improved, under packing plant conditions and speeds, to a level close to that of expert graders applying grades at a comfortable rate of speed offline.

  5. Bruxism defined and graded: an international consensus.

    PubMed

    Lobbezoo, F; Ahlberg, J; Glaros, A G; Kato, T; Koyano, K; Lavigne, G J; de Leeuw, R; Manfredini, D; Svensson, P; Winocur, E

    2013-01-01

    To date, there is no consensus about the definition and diagnostic grading of bruxism. A written consensus discussion was held among an international group of bruxism experts as to formulate a definition of bruxism and to suggest a grading system for its operationalisation. The expert group defined bruxism as a repetitive jaw-muscle activity characterised by clenching or grinding of the teeth and/or by bracing or thrusting of the mandible. Bruxism has two distinct circadian manifestations: it can occur during sleep (indicated as sleep bruxism) or during wakefulness (indicated as awake bruxism). For the operationalisation of this definition, the expert group proposes a diagnostic grading system of 'possible', 'probable' and 'definite' sleep or awake bruxism. The proposed definition and grading system are suggested for clinical and research purposes in all relevant dental and medical domains. © 2012 Blackwell Publishing Ltd.

  6. Tranpsort phenomena in solidification processing of functionally graded materials

    NASA Astrophysics Data System (ADS)

    Gao, Juwen

    A combined numerical and experimental study of the transport phenomena during solidification processing of metal matrix composite functionally graded materials (FGMs) is conducted in this work. A multiphase transport model for the solidification of metal-matrix composite FGMs has been developed that accounts for macroscopic particle segregation due to liquid-particle flow and particle-solid interactions. An experimental study has also been conducted to gain physical insight as well as to validate the model. A novel method to in-situ measure the particle volume fraction using fiber optic probes is developed for transparent analogue solidification systems. The model is first applied to one-dimensional pure matrix FGM solidification under gravity or centrifugal field and is extensively validated against the experimental results. The mechanisms for the formation of particle concentration gradient are identified. Two-dimensional solidification of pure matrix FGM with convection is then studied using the model as well as experiments. The interaction among convection flow, solidification process and the particle transport is demonstrated. The results show the importance of convection in the particle concentration gradient formation. Then, simulations for alloy FGM solidification are carried out for unidirectional solidification as well as two-dimensional solidification with convection. The interplay among heat and species transport, convection and particle motion is investigated. Finally, future theoretical and experimental work is outlined.

  7. Perception of Science Standards' Effectiveness and Their Implementation by Science Teachers

    NASA Astrophysics Data System (ADS)

    Klieger, Aviva; Yakobovitch, Anat

    2011-06-01

    The introduction of standards into the education system poses numerous challenges and difficulties. As with any change, plans should be made for teachers to understand and implement the standards. This study examined science teachers' perceptions of the effectiveness of the standards for teaching and learning, and the extent and ease/difficulty of implementing science standards in different grades. The research used a mixed methods approach, combining qualitative and quantitative research methods. The research tools were questionnaires that were administered to elementary school science teachers. The majority of the teachers perceived the standards in science as effective for teaching and learning and only a small minority viewed them as restricting their pedagogical autonomy. Differences were found in the extent of implementation of the different standards and between different grades. The teachers perceived a different degree of difficulty in the implementation of the different standards. The standards experienced as easiest to implement were in the field of biology and materials, whereas the standards in earth sciences and the universe and technology were most difficult to implement, and are also those evaluated by the teachers as being implemented to the least extent. Exposure of teachers' perceptions on the effectiveness of standards and the implementation of the standards may aid policymakers in future planning of teachers' professional development for the implementation of standards.

  8. Accountability and Grade Inflation in a Rural School.

    ERIC Educational Resources Information Center

    Goodwin, Deborah Hayes; Holman, David M.

    In an effort to hold schools accountable, Arkansas added grade inflation into the accountability system. The Arkansas Legislature mandated that the Arkansas Department of Education identify high schools with "statistically significant variance" between students' grade point averages (GPAs) and ACT performances. A grade inflation index…

  9. Reliability of macroscopic grading of intervertebral disk degeneration in dogs by use of the Thompson system and comparison with low-field magnetic resonance imaging findings.

    PubMed

    Bergknut, Niklas; Grinwis, Guy; Pickee, Emile; Auriemma, Edoardo; Lagerstedt, Anne-Sofie; Hagman, Ragnvi; Hazewinkel, Herman A W; Meij, Björn P

    2011-07-01

    To evaluate the reliability of the Thompson system for use in grading the gross pathological changes of intervertebral disk (IVD) degeneration in dogs and to investigate the agreement between gross pathological findings and low-field (0.2-T) magnetic resonance imaging (MRI) findings. Vertebral columns from cadavers of 19 dogs of various ages, breeds, and origins. 182 intervertebral segments were collected from 19 canine cadavers. Sagittal T2-weighted MRI of the T11 through S1 portion of the vertebral column was performed within 24 hours after the dogs were euthanized. The vertebral columns were subsequently divided in the midsagittal plane, and high-resolution photographs were obtained of each intervertebral segment (end plate-disk-end plate). The MRI images and photographs were graded separately in a blinded manner by 4 observers who used both Pfirrmann and Thompson grading criteria. The interobserver agreement for Thompson scores ranged from 0.76 to 0.88, and the intraobserver agreement ranged from 0.88 to 0.94 (Cohen weighted κ analysis). Agreement between scores for the Pfirrmann and Thompson grading criteria was κ = 0.70. Grading of IVD degeneration in dogs by use of the Thompson system resulted in high interobserver and intraobserver agreement, and scores for the Thompson system had substantial agreement with low-field MRI findings graded by use of the Pfirrmann system. This suggested that low-field MRI can be used to diagnose IVD degeneration in dogs.

  10. Application of a novel severity grading system for surgical complications after colorectal resection.

    PubMed

    Mazeh, Haggi; Samet, Yacov; Abu-Wasel, Bassam; Beglaibter, Nahum; Grinbaum, Ronit; Cohen, Tzeela; Pinto, Meir; Hamburger, Tamar; Freund, Herbert R; Nissan, Aviram

    2009-03-01

    Uniform and accurate reporting of surgical complications is the basis for quality control. We developed a computerized system for reporting and grading surgical complications in colorectal surgery. This study was conducted to evaluate this computerized reporting system. A retrospective chart review was conducted of all surgical complications in patients who underwent resection of the colon or rectum at our institution between the years 1999 and 2004 (n = 408). All complications were recorded using the computerized reporting system and compared with complications reported in the literature. Elective operations were performed in 75.7% of patients, and 24.3% required emergency operations. Of the 408 patients in the study, 239 (58.6%) had an uneventful recovery without complications. At least 1 complication was recorded in 169 (41.4%) patients. Grades 1 and 2 complications were recorded in 83 (20.3%) and 105 (25.7%) patients, respectively, requiring observation or medical treatment only, and 59 patients (14.5%) had grades 3 to 5 complications. The three leading complications were surgical site infection, intraabdominal abscess, and hemorrhage requiring blood transfusion. The grades 3 to 5 complication rate was within the range described in the literature, and the rate of grades 1 and 2 complications was substantially higher. These grades 1 and 2 complications were associated with a substantially longer hospital stay. This novel complication reporting system was found feasible and proved to have a higher sensitivity for recording minor but meaningful complications that tend to prolong hospital stay.

  11. The SCHEIE Visual Field Grading System

    PubMed Central

    Sankar, Prithvi S.; O’Keefe, Laura; Choi, Daniel; Salowe, Rebecca; Miller-Ellis, Eydie; Lehman, Amanda; Addis, Victoria; Ramakrishnan, Meera; Natesh, Vikas; Whitehead, Gideon; Khachatryan, Naira; O’Brien, Joan

    2017-01-01

    Objective No method of grading visual field (VF) defects has been widely accepted throughout the glaucoma community. The SCHEIE (Systematic Classification of Humphrey visual fields-Easy Interpretation and Evaluation) grading system for glaucomatous visual fields was created to convey qualitative and quantitative information regarding visual field defects in an objective, reproducible, and easily applicable manner for research purposes. Methods The SCHEIE grading system is composed of a qualitative and quantitative score. The qualitative score consists of designation in one or more of the following categories: normal, central scotoma, paracentral scotoma, paracentral crescent, temporal quadrant, nasal quadrant, peripheral arcuate defect, expansive arcuate, or altitudinal defect. The quantitative component incorporates the Humphrey visual field index (VFI), location of visual defects for superior and inferior hemifields, and blind spot involvement. Accuracy and speed at grading using the qualitative and quantitative components was calculated for non-physician graders. Results Graders had a median accuracy of 96.67% for their qualitative scores and a median accuracy of 98.75% for their quantitative scores. Graders took a mean of 56 seconds per visual field to assign a qualitative score and 20 seconds per visual field to assign a quantitative score. Conclusion The SCHEIE grading system is a reproducible tool that combines qualitative and quantitative measurements to grade glaucomatous visual field defects. The system aims to standardize clinical staging and to make specific visual field defects more easily identifiable. Specific patterns of visual field loss may also be associated with genetic variants in future genetic analysis. PMID:28932621

  12. Causal Loop Analysis of coastal geomorphological systems

    NASA Astrophysics Data System (ADS)

    Payo, Andres; Hall, Jim W.; French, Jon; Sutherland, James; van Maanen, Barend; Nicholls, Robert J.; Reeve, Dominic E.

    2016-03-01

    As geomorphologists embrace ever more sophisticated theoretical frameworks that shift from simple notions of evolution towards single steady equilibria to recognise the possibility of multiple response pathways and outcomes, morphodynamic modellers are facing the problem of how to keep track of an ever-greater number of system feedbacks. Within coastal geomorphology, capturing these feedbacks is critically important, especially as the focus of activity shifts from reductionist models founded on sediment transport fundamentals to more synthesist ones intended to resolve emergent behaviours at decadal to centennial scales. This paper addresses the challenge of mapping the feedback structure of processes controlling geomorphic system behaviour with reference to illustrative applications of Causal Loop Analysis at two study cases: (1) the erosion-accretion behaviour of graded (mixed) sediment beds, and (2) the local alongshore sediment fluxes of sand-rich shorelines. These case study examples are chosen on account of their central role in the quantitative modelling of geomorphological futures and as they illustrate different types of causation. Causal loop diagrams, a form of directed graph, are used to distil the feedback structure to reveal, in advance of more quantitative modelling, multi-response pathways and multiple outcomes. In the case of graded sediment bed, up to three different outcomes (no response, and two disequilibrium states) can be derived from a simple qualitative stability analysis. For the sand-rich local shoreline behaviour case, two fundamentally different responses of the shoreline (diffusive and anti-diffusive), triggered by small changes of the shoreline cross-shore position, can be inferred purely through analysis of the causal pathways. Explicit depiction of feedback-structure diagrams is beneficial when developing numerical models to explore coastal morphological futures. By explicitly mapping the feedbacks included and neglected within a model, the modeller can readily assess if critical feedback loops are included.

  13. The Project MACULA Retinal Pigment Epithelium Grading System for Histology and Optical Coherence Tomography in Age-Related Macular Degeneration

    PubMed Central

    Zanzottera, Emma C.; Messinger, Jeffrey D.; Ach, Thomas; Smith, R. Theodore; Freund, K. Bailey; Curcio, Christine A.

    2015-01-01

    Purpose. To seek pathways of retinal pigment epithelium (RPE) fate in age-related macular degeneration via a morphology grading system; provide nomenclature, visualization targets, and metrics for clinical imaging and model systems. Methods. Donor eyes with geographic atrophy (GA) or choroidal neovascularization (CNV) and one GA eye with previous clinical spectral-domain optical coherence tomography (SDOCT) imaging were processed for histology, photodocumented, and annotated at predefined locations. Retinal pigment epithelial cells contained spindle-shaped melanosomes, apposed a basal lamina or basal laminar deposit (BLamD), and exhibited recognizable morphologies. Thicknesses and unbiased estimates of frequencies were obtained. Results. In 13 GA eyes (449 locations), ‘Shedding,’ ‘Sloughed,’ and ‘Dissociated’ morphologies were abundant; 22.2% of atrophic locations had ‘Dissociated’ RPE. In 39 CNV eyes (1363 locations), 37.3% of locations with fibrovascular/fibrocellular scar had ‘Entombed’ RPE; ‘Sloughed,’ ‘Dissociated,’ and ‘Bilaminar’ morphologies were abundant. Of abnormal RPE, CNV and GA both had ∼35% ‘Sloughed’/‘Intraretinal,’ with more Intraretinal in CNV (9.5% vs. 1.8%). ‘Shedding’ cells associated with granule aggregations in BLamD. The RPE layer did not thin, and BLamD remained thick, with progression. Granule-containing material consistent with three morphologies correlated to SDOCT hyperreflective foci in the previously examined GA patient. Conclusions. Retinal pigment epithelium morphology indicates multiple pathways in GA and CNV. Atrophic/scarred areas have numerous cells capable of transcribing genes and generating imaging signals. Shed granule aggregates, possibly apoptotic, are visible in SDOCT, as are ‘Dissociated’ and ‘Sloughed’ cells. The significance of RPE phenotypes is addressable in longitudinal, high-resolution imaging in clinic populations. Data can motivate future molecular phenotyping studies. PMID:25813989

  14. Gender, age, and psychosocial context of the perception of facial esthetics.

    PubMed

    Tole, Nikoleta; Lajnert, Vlatka; Kovacevic Pavicic, Daniela; Spalj, Stjepan

    2014-01-01

    To explore the effects of gender, age, and psychosocial context on the perception of facial esthetics. The study included 1,444 Caucasian subjects aged 16 to 85 years. Two sets of color photographs illustrating 13 male and 13 female Caucasian facial type alterations, representing different skeletal and dentoalveolar components of sagittal maxillary-mandibular relationships, were used to estimate the facial profile attractiveness. The examinees graded the profiles based on a 0 to 10 numerical rating scale. The examinees graded the profiles of their own sex only from a social perspective, whereas opposite sex profiles were graded both from the social and emotional perspective separately. The perception of facial esthetics was found to be related to the gender, age, and psychosocial context of evaluation (p < 0.05). The most attractive profiles to men are the orthognathic female profile from the social perspective and the moderate bialveolar protrusion from the emotional perspective. The most attractive profile to women is the orthognathic male profile, when graded from the social aspect, and the mild bialveolar retrusion when graded from the emotional aspect. The age increase of the assessor results in a higher attractiveness grade. When planning treatment that modifies the facial profile, the clinician should bear in mind that the perception of facial profile esthetics is a complex phenomenon influenced by biopsychosocial factors. This study allows a better understanding of the concept of perception of facial esthetics that includes gender, age, and psychosocial context. © 2013 Wiley Periodicals, Inc.

  15. Independent Contributions of the Central Executive, Intelligence, and In-Class Attentive Behavior to Developmental Change in the Strategies Used to Solve Addition Problems

    PubMed Central

    Geary, David C.; Hoard, Mary K.; Nugent, Lara

    2012-01-01

    Children’s (n = 275) use of retrieval, decomposition (e.g., 7 = 4+3, and thus 6+7=6+4+3), and counting to solve additional problems was longitudinally assessed from first to fourth grade, and intelligence, working memory, and in-class attentive behavior was assessed in one or several grades. The goal was to assess the relation between capacity of the central executive component of working memory, controlling for intelligence and in-class attentive behavior, and grade-related changes in children’s use of these strategies. The predictor on intercept effects from multilevel models revealed that children with higher central executive capacity correctly retrieved more facts and used the most sophisticated counting procedure more frequently and accurately than did their lower capacity peers at the beginning of first grade, but the predictor on slope effects indicated that this advantage disappeared (retrieval) or declined in importance (counting) from first to fourth grade. The predictor on slope effects also revealed that from first through fourth grade, children with higher capacity adopted the decomposition strategy more quickly than did other children. The results remained robust with controls for children’s sex, race, school site, speed of encoding Arabic numerals and articulating number words, and mathematics achievement in kindergarten. The results also revealed that intelligence and in-class attentive behavior independently contributed to children’s strategy development. PMID:22698947

  16. The Effect of the DISTAR Instructional System on First and Second Grade Achievement: An Evaluation of the 1971-1972 Title I Program of Winthrop, Massachusetts.

    ERIC Educational Resources Information Center

    Kaufman, Maurice

    The Distar I Reading, Language and Arithmetic programs were used with two first grade classes. The Distar II programs were used with two second grade classes. One first grade Distar class appeared to make some progress in oral language. Comparison of the first grade Distar classes with a first grade control class that used a Scott-Foresman basal…

  17. Development of Grading Systems for Short-Length Lumber

    Treesearch

    Eugene M. Wengert; Robert W. Rice; James G. Schroeder

    1987-01-01

    The abundance of low grade hardwood timber and a shortage of high grade timber of many species has led to the examination of alternative processing methods for converting logs to lumber. However, present grading rules for short length lumber are not good predictors of the lumber's true value. A new method of grading short length lumber is proposed, with furniture...

  18. A Study of the Results of the Implementation of a Non-Punitive Grading Practice at Mattatuck Community College.

    ERIC Educational Resources Information Center

    Maxwell, James

    Mattatuck Community College implemented non-punitive grading practices into its grading system in the Fall 1973 semester. These practices centered about the elimination of plus and minus grades, elimination of the grade of F, and liberalizing the course withdrawal policy to allow for withdrawal without penalty throughout the semester. A comparison…

  19. The Impact of Classroom Performance System-Based Instruction with Peer Instruction upon Student Achievement and Motivation in Eighth Grade Math Students

    ERIC Educational Resources Information Center

    Allison, Tracy Michelle Hunter

    2012-01-01

    The researcher employed two designs to address the research question for this particular study. This quasi-experimental non-equivalent control group study compared the math achievement of 92 eighth grade students who received Classroom Performance System (CPS)-based instruction using Peer Instruction (PI) to 76 eighth grade students who received…

  20. TRSys: A hardwood lumber grading training and remanufacturing system

    Treesearch

    P. Klinkhachorn; R. Kothari; R. Annavajjhala; Charles W. McMillin

    1994-01-01

    The Training and Remanufacturing System (TRSys) is a new training tool for teaching both hardwood lumber grading and remanufacturing of lower grade boards into smaller boards of higher total value. TRSys is based on the HaLT2, ReGS, and enhanced HaRem computer programs. The most important feature of this new program is its ablilty to evaluate remanufacturing beyond...

  1. TRSys: a hardwood lumber grading training and remanufacturing system

    Treesearch

    P. Klinkhachorn; R. Kotharl; R. annavajjhala; Charles W. McMilling

    1994-01-01

    The training and remanufacturing system( TRsys) is a new training tool for teaching both hardwood lumber and grading and remanufacturing of lower grade boards into smaller boards of higher total value. TRSys is based on HaLT2. REGS, and enhanced HARem computer programs. The mosti mportant feature of this new program is its ability to evaluate remanufacturing beyond...

  2. The Most Preferred and Effective Reviewer of L2 Writing among Automated Grading System, Peer Reviewer and Teacher

    ERIC Educational Resources Information Center

    Tsai, Min-Hsiu

    2017-01-01

    Who is the most preferred and deemed the most helpful reviewer in improving student writing? This study exercised a blended teaching method which consists of three currently prevailing reviewers: the automated grading system (AGS, a web-based method), the peer review (a process-oriented approach), and the teacher grading technique (the…

  3. Social Validity of the Social Skills Improvement System--Classwide Intervention Program (SSIS-CIP) in the Primary Grades

    ERIC Educational Resources Information Center

    Wollersheim Shervey, Sarah; Sandilos, Lia E.; DiPerna, James C.; Lei, Pui-Wa

    2017-01-01

    The purpose of this study was to examine the social validity of the Social Skills Improvement System--Classwide Intervention Program (SSIS-CIP) for teachers in the primary grades. Participants included 45 first and second grade teachers who completed a 16-item social validity questionnaire during each year of the SSIS-CIP efficacy trial. Findings…

  4. Social Validity of the Social Skills Improvement System--Classwide Intervention Program (SSIS-CIP) in the Primary Grades

    ERIC Educational Resources Information Center

    Wollersheim Shervey, Sarah; Sandilos, Lia E.; DiPerna, James C.; Lei, Pui-Wa

    2017-01-01

    The purpose of this study was to examine the social validity of the Social Skills Improvement System-Classwide Intervention Program (SSIS-CIP) for teachers in the primary grades. Participants included 45 first and second grade teachers who completed a 16-item social validity questionnaire during each year of the SSIS-CIP efficacy trial. Findings…

  5. Automated grading, upgrading, and cuttings prediction of surfaced dry hardwood lumber

    Treesearch

    Sang-Mook Lee; Phil Araman; A.Lynn Abbott; Matthew F. Winn

    2010-01-01

    This paper concerns the scanning, sawing, and grading of kiln-dried hardwood lumber. A prototype system is described that uses laser sources and a video camera to scan boards. The system automatically detects defects and wane, searches for optimal sawing solutions, and then estimates the grades of the boards that would result. The goal is to derive maximum commercial...

  6. Hardwood lumber scanning tests to determine NHLA lumber grades

    Treesearch

    Philip A. Araman; Ssang-Mook Lee; A. Lynn Abbott; Matthew F. Winn

    2011-01-01

    This paper concerns the scanning, and grading of kiln-dried hardwood lumber. A prototype system is described that uses laser sources and a video camera to scan boards. The system automatically detects defects and wane, grades the boards, and then searches for higher value boards within the original board. The goal is to derive maximum commercial value based on current...

  7. Development of a cost-effective machine vision system for in-field sorting and grading of apples: Fruit orientation and size estimation

    USDA-ARS?s Scientific Manuscript database

    The objective of this research was to develop an in-field apple presorting and grading system to separate undersized and defective fruit from fresh market-grade apples. To achieve this goal, a cost-effective machine vision inspection prototype was built, which consisted of a low-cost color camera, L...

  8. Use of an audience response system (ARS) in a dual-campus classroom environment.

    PubMed

    Medina, Melissa S; Medina, Patrick J; Wanzer, Donald S; Wilson, Jane E; Er, Nelson; Britton, Mark L

    2008-04-15

    To implement an audience response system in a dual-campus classroom that aggregated data during graded (attendance and quizzes) and non-graded classroom activities (formative quizzes, case discussions, examination reviews, and team activities) and explore its strengths, weaknesses, and impact on active learning. After extensive research, an appropriate audience response system was selected and implemented in a dual-classroom setting for a third-year required PharmD course. Students were assigned a clicker and training and policies regarding clicker use were reviewed. Activities involving clicker use were carefully planned to simultaneously engage students in both classrooms in real time. Focus groups were conducted with students to gather outcomes data. Students and faculty members felt that the immediate feedback the automated response system (ARS) provided was most beneficial during non-graded activities. Student anxiety increased with use of ARS during graded activities due to fears regarding technology failure, user error, and academic integrity. ARS is a viable tool for increasing active learning in a doctor of pharmacy (PharmD) program, especially when used for non-graded class activities. Faculty members should proceed cautiously with using ARS for graded classroom activities and develop detailed and documented policies for ARS use.

  9. Grading for Understanding--Standards-Based Grading

    ERIC Educational Resources Information Center

    Zimmerman, Todd

    2017-01-01

    Standards-based grading (SBG), sometimes called learning objectives-based assessment (LOBA), is an assessment model that relies on students demonstrating mastery of learning objectives (sometimes referred to as standards). The goal of this grading system is to focus students on mastering learning objectives rather than on accumulating points. I…

  10. Susceptibility Imaging in Glial Tumor Grading; Using 3 Tesla Magnetic Resonance (MR) System and 32 Channel Head Coil.

    PubMed

    Aydin, Omer; Buyukkaya, Ramazan; Hakyemez, Bahattin

    2017-01-01

    Susceptibility weighted imaging (SWI) is a velocity compensated, high-resolution three-dimensional (3D) spoiled gradient-echo sequence that uses magnitude and filtered-phase data. SWI seems to be a valuable tool for non-invasive evaluation of central nervous system gliomas. Relative cerebral blood volume (rCBV) ratio is one of the best noninvasive methods for glioma grading. Degree of intratumoral susceptibility signal (ITSS) on SWI correlates with rCBV ratio and histopathological grade. This study investigated the effectiveness of ITSS grading and rCBV ratio in preoperative assessment. Thirty-one patients (17 males and 14 females) with histopathogical diagnosis of glial tumor undergoing routine cranial MRI, SWI, and perfusion MRI examinations between October 2011 and July 2013 were retrospectively enrolled. All examinations were performed using 3T apparatus with 32-channel head coil. We used ITSS number for SWI grading. Correlations between SWI grade, rCBV ratio, and pathological grading were evaluated. ROC analysis was performed to determine the optimal rCBV ratio to distinguish between high-grade and low-grade glial tumors. There was a strong positive correlation between both pathological and SWI grading. We determined the optimal rCBV ratio to discriminate between high-grade and low-grade tumors to be 2.21. In conclusion, perfusion MRI and SWI using 3T MR and 32-channel head coil may provide useful information for preoperative glial tumor grading. SWI can be used as an accessory to perfusion MR technique in preoperative tumor grading.

  11. 78 FR 33146 - Importance of Clear Safety Procedures for Temporary Removal From Service of Highway-Rail Grade...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-03

    ... Systems and Wayside Signal Systems AGENCY: Federal Railroad Administration (FRA), Department of... traveling public and railroad employees when highway- rail grade crossing warning systems and wayside signal systems are temporarily removed from service for purposes of testing, inspection, maintenance, or repair...

  12. The Minnesota Grading System of eye bank eyes for age-related macular degeneration.

    PubMed

    Olsen, Timothy W; Feng, Xiao

    2004-12-01

    The Minnesota Grading System (MGS) is a method to evaluate human eye bank eyes and determine the level of age-related macular degeneration (AMD), by using criteria and definitions from the Age-Related Eye Disease Study (AREDS). Donor eyes (108 pairs) from the Minnesota Lions Eye Bank were cut circumferentially at the pars plana to remove the anterior segment. A 1000 +/- 2.5-microm ruby sphere was placed on the optic nerve as a size reference. A digital, high-resolution, color macular photograph was taken through a dissecting microscope. The neurosensory retina was removed from one globe of the pair. The underlying retinal pigment epithelium was rephotographed, localizing the fovea with a proportional triangle. A grid was superimposed in the macular photographs and images were graded according to AREDS criteria. Twenty pairs were dissected bilaterally and graded for symmetry. Eighty-eight globes were graded into one of four MGS categories. Nineteen (95%) of 20 globes had symmetric grades. The MGS provides a methodology to grade donor tissue from eye bank eyes to correspond to the AREDS classification system. Donor tissue may be used for subsequent molecular analysis, including genomics and proteomics.

  13. Revised definition of neuropathic pain and its grading system: an open case series illustrating its use in clinical practice.

    PubMed

    Geber, Christian; Baumgärtner, Ulf; Schwab, Rainer; Müller, Harald; Stoeter, Peter; Dieterich, Marianne; Sommer, Clemens; Birklein, Frank; Treede, Rolf-Detlef

    2009-10-01

    The definition of neuropathic pain has recently been revised by an expert committee of the Neuropathic Pain Special Interest Group of the International Association for the Study of Pain (NeuPSIG) as "pain arising as direct consequence of a lesion or disease affecting the somatosensory system," and a grading system of "definite," "probable," and "possible" neuropathic pain has been introduced. This open case series of 5 outpatients (3 men, 2 women; mean age 48 +/- 12 years) demonstrates how the grading system can be applied, in combination with appropriate confirmatory testing, to diagnosis neuropathic conditions in clinical practice. The proposed grading system includes a dynamic algorithm that enhances the physician's ability to determine with a greater level of certainty whether a pain condition is neuropathic. Its clinical use should be further validated in prospective studies.

  14. NASA Tech Briefs, November 2007

    NASA Technical Reports Server (NTRS)

    2007-01-01

    Topics include: Wireless Measurement of Contact and Motion Between Contact Surfaces; Wireless Measurement of Rotation and Displacement Rate; Portable Microleak-Detection System; Free-to-Roll Testing of Airplane Models in Wind Tunnels; Cryogenic Shrouds for Testing Thermal-Insulation Panels; Optoelectronic System Measures Distances to Multiple Targets; Tachometers Derived From a Brushless DC Motor; Algorithm-Based Fault Tolerance for Numerical Subroutines; Computational Support for Technology- Investment Decisions; DSN Resource Scheduling; Distributed Operations Planning; Phase-Oriented Gear Systems; Freeze Tape Casting of Functionally Graded Porous Ceramics; Electrophoretic Deposition on Porous Non- Conductors; Two Devices for Removing Sludge From Bioreactor Wastewater; Portable Unit for Metabolic Analysis; Flash Diffusivity Technique Applied to Individual Fibers; System for Thermal Imaging of Hot Moving Objects; Large Solar-Rejection Filter; Improved Readout Scheme for SQUID-Based Thermometry; Error Rates and Channel Capacities in Multipulse PPM; Two Mathematical Models of Nonlinear Vibrations; Simpler Adaptive Selection of Golomb Power-of- Two Codes; VCO PLL Frequency Synthesizers for Spacecraft Transponders; Wide Tuning Capability for Spacecraft Transponders; Adaptive Deadband Synchronization for a Spacecraft Formation; Analysis of Performance of Stereoscopic-Vision Software; Estimating the Inertia Matrix of a Spacecraft; Spatial Coverage Planning for Exploration Robots; and Increasing the Life of a Xenon-Ion Spacecraft Thruster.

  15. Social validity of the Social Skills Improvement System-Classwide Intervention Program (SSIS-CIP) in the primary grades.

    PubMed

    Wollersheim Shervey, Sarah; Sandilos, Lia E; DiPerna, James C; Lei, Pui-Wa

    2017-09-01

    The purpose of this study was to examine the social validity of the Social Skills Improvement System-Classwide Intervention Program (SSIS-CIP) for teachers in the primary grades. Participants included 45 first and second grade teachers who completed a 16-item social validity questionnaire during each year of the SSIS-CIP efficacy trial. Findings indicated that teachers generally perceived the SSIS-CIP as a socially valid and feasible intervention for primary grades; however, teachers' ratings regarding ease of implementation and relevance and sequence demonstrated differences across grade levels in the second year of implementation. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  16. Comparison of severity classification in Japanese patients with antineutrophil cytoplasmic antibody-associated vasculitis in a nationwide, prospective, inception cohort study.

    PubMed

    Sada, Ken-Ei; Harigai, Masayoshi; Amano, Koichi; Atsumi, Tatsuya; Fujimoto, Shouichi; Yuzawa, Yukio; Takasaki, Yoshinari; Banno, Shogo; Sugihara, Takahiko; Kobayashi, Masaki; Usui, Joichi; Yamagata, Kunihiro; Homma, Sakae; Dobashi, Hiroaki; Tsuboi, Naotake; Ishizu, Akihiro; Sugiyama, Hitoshi; Okada, Yasunori; Arimura, Yoshihiro; Matsuo, Seiichi; Makino, Hirofumi

    2016-09-01

    To compare disease severity classification systems for six-month outcome prediction in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). Patients with newly diagnosed AAV from 53 tertiary institutions were enrolled. Six-month remission, overall survival, and end-stage renal disease (ESRD)-free survival were evaluated. According to the European Vasculitis Study Group (EUVAS)-defined disease severity, the 321 enrolled patients were classified as follows: 14, localized; 71, early systemic; 170, generalized; and 66, severe disease. According to the rapidly progressive glomerulonephritis (RPGN) clinical grading system, the patients were divided as follows: 60, grade I; 178, grade II; 66, grade III; and 12, grade IV. According to the Five-Factor Score (FFS) 2009, 103, 109, and 109 patients had ≤1, 2, and ≥3 points, respectively. No significant difference in remission rates was found in any severity classification. The overall and ESRD-free survival rates significantly differed between grades I/II, III, and IV, regardless of renal involvement. Severe disease was a good predictor of six-month overall and ESRD-free survival. The FFS 2009 was useful to predict six-month ESRD-free survival but not overall survival. The RPGN grading system was more useful to predict six-month overall and ESRD-free survival than the EUVAS-defined severity or FFS 2009.

  17. 25 CFR 36.30 - Standard X-Grading requirements.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 25 Indians 1 2012-04-01 2011-04-01 true Standard X-Grading requirements. 36.30 Section 36.30 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION MINIMUM ACADEMIC STANDARDS FOR THE... Evaluation § 36.30 Standard X—Grading requirements. (a) Each school shall implement a uniform grading system...

  18. 25 CFR 36.30 - Standard X-Grading requirements.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 25 Indians 1 2013-04-01 2013-04-01 false Standard X-Grading requirements. 36.30 Section 36.30 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION MINIMUM ACADEMIC STANDARDS FOR THE... Evaluation § 36.30 Standard X—Grading requirements. (a) Each school shall implement a uniform grading system...

  19. 25 CFR 36.30 - Standard X-Grading requirements.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false Standard X-Grading requirements. 36.30 Section 36.30 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION MINIMUM ACADEMIC STANDARDS FOR THE... Evaluation § 36.30 Standard X—Grading requirements. (a) Each school shall implement a uniform grading system...

  20. 25 CFR 36.30 - Standard X-Grading requirements.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 25 Indians 1 2014-04-01 2014-04-01 false Standard X-Grading requirements. 36.30 Section 36.30 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR EDUCATION MINIMUM ACADEMIC STANDARDS FOR THE... Evaluation § 36.30 Standard X—Grading requirements. (a) Each school shall implement a uniform grading system...

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