Persistent Identifiers for Data Products: Adoption, Enhancement, and Use

NASA Astrophysics Data System (ADS)

Downs, R. R.; Schumacher, J.; Scialdone, J.; Hansen, M.

2016-12-01

Persistent identifiers offer value for science and for various science community stakeholders, such as data producers, data distributers, science article authors, scientific journal publishers, research sponsors, libraries, and affiliated institutions. However, to attain the benefits of persistent identifiers, they should be assigned to disseminated data products and included within the references reported in publications that describe the studies in which the data were used. Scientific data centers, archives, digital repositories, and other data publishers also need to determine the level of aggregation, or granularity, of data products to be assigned persistent identifiers as well as the elements to be included in the landing pages to which persistent identifiers will resolve. Similarly, policies and procedures should be clear on decisions about maintenance issues, including versioning of data products and how persistent identifiers to previous versions and new locations will be maintained. With some persistent identifiers, such as Digital Object Identifiers (DOIs), which provide capabilities to link to related identifiers of other works, decisions on the establishment of links also must be clear, including links between early versions of data products and subsequent versions, links between data products and associated documentation, and links between data products and other publications that describe the data. We describe decisions for enabling the adoption and assignment of DOIs as persistent identifiers for data products disseminated by the NASA Socioeconomic Data and Applications Center (SEDAC) along with considerations for policy decisions, testing, implementation, and enhancement. The prevalence of the adoption of DOIs for citing the use of Earth science data disseminated by SEDAC also is described to provide insight into how interdisciplinary data users have engaged in the use of DOIs within their publications along with the implications of such use.

A Data Model and Task Space for Data of Interest (DOI) Eye-Tracking Analyses.

PubMed

Jianu, Radu; Alam, Sayeed Safayet

2018-03-01

Eye-tracking data is traditionally analyzed by looking at where on a visual stimulus subjects fixate, or, to facilitate more advanced analyses, by using area-of-interests (AOI) defined onto visual stimuli. Recently, there is increasing interest in methods that capture what users are looking at rather than where they are looking. By instrumenting visualization code that transforms a data model into visual content, gaze coordinates reported by an eye-tracker can be mapped directly to granular data shown on the screen, producing temporal sequences of data objects that subjects viewed in an experiment. Such data collection, which is called gaze to object mapping (GTOM) or data-of-interest analysis (DOI), can be done reliably with limited overhead and can facilitate research workflows not previously possible. Our paper contributes to establishing a foundation of DOI analyses by defining a DOI data model and highlighting its differences to AOI data in structure and scale; by defining and exemplifying a space of DOI enabled tasks; by describing three concrete examples of DOI experimentation in three different domains; and by discussing immediate research challenges in creating a framework of visual support for DOI experimentation and analysis.

Tectonic Storytelling with Open Source and Digital Object Identifiers - a case study about Plate Tectonics and the Geopark Bergstraße-Odenwald

NASA Astrophysics Data System (ADS)

Löwe, Peter; Barmuta, Jan; Klump, Jens; Neumann, Janna; Plank, Margret

2014-05-01

The communication of advances in research to the common public for both education and decision making is an important aspect of scientific work. An even more crucial task is to gain recognition within the scientific community, which is judged by impact factor and citation counts. Recently, the latter concepts have been extended from textual publications to include data and software publications. This paper presents a case study for science communication and data citation. For this, tectonic models, Free and Open Source Software (FOSS), best practices for data citation and a multimedia online-portal for scientific content are combined. This approach creates mutual benefits for the stakeholders: Target audiences receive information on the latest research results, while the use of Digital Object Identifiers (DOI) increases the recognition and citation of underlying scientific data. This creates favourable conditions for every researcher as DOI names ensure citeability and long term availability of scientific research. In the developed application, the FOSS tool for tectonic modelling GPlates is used to visualise and manipulate plate-tectonic reconstructions and associated data through geological time. These capabilities are augmented by the Science on a Halfsphere project (SoaH) with a robust and intuitive visualisation hardware environment. The tectonic models used for science communication are provided by the AGH University of Science and Technology. They focus on the Silurian to Early Carboniferous evolution of Central Europe (Bohemian Massif) and were interpreted for the area of the Geopark Bergstraße Odenwald based on the GPlates/SoaH hardware- and software stack. As scientific story-telling is volatile by nature, recordings are a natural means of preservation for further use, reference and analysis. For this, the upcoming portal for audiovisual media of the German National Library of Science and Technology TIB is expected to become a critical service

Impact location of objects hitting the water surface

NASA Astrophysics Data System (ADS)

Kadri, Usama

2017-04-01

Analysis of data, recorded on March 8th 2014 at the Comprehensive Test ban Treaty Organisation's hydroacoustic station off Cape Leeuwin Western Australia, reveal pressure signatures of objects impacting at the sea surface which could be associated with falling meteorites as well as the missing Malaysian MH370 airplane. The location of the sources are identified analytically by an inverse solution based on acoustic-gravity wave theory (e.g. see references below) which have been developed and validated experimentally. Apart from the direct contribution to the search efforts after the missing airplane, the method we describe here is very efficient for identifying the location of sources that result in a sudden change in the water pressure in general. References 1. T.Yamamoto,1982.Gravity waves and acoustic waves generated by submarine earthquakes, Soil Dyn. Earthquake Eng., 1, 75-82. 2. M. Stiassnie, 2010. Tsunamis and acoustic-gravity waves from underwater earthquakes, J. Eng. Math., 67, 23-32, doi:10.1007/s10665-009-9323-x. 3. U. Kadri and M. Staissnie, 2012. Acoustic-gravity waves interacting with the shelf break. J. Geophys. Res., 117, C03035, doi: 10.1029/2011JC007674. 4. E. Eyov, A. Klar, U. Kadri and M. Stiassnie, 2013. Progressive waves in a compressible ocean with elastic bottom, Wave Motion 50, 929-939. doi: 10.1016/j.wavemoti.2013.03.003 5. G. Hendin and M. Stiassnie, 2013. Tsunami and acoustic-gravity waves in water of constant depth, Phys. Fluids 25, 086103, doi: 10.1063/1.481799. 6. U. Kadri, 2016. Acoustic-gravity waves from an oscillating ice-block in arctic zones. Advances in Acoustics and Vibration, 8076108, http://dx.doi.org/10.1155/2016/8076108 7. T.C.A. Oliveira, U. Kadri, 2016. Acoustic-gravity waves from the 2004 Indian Ocean earthquake and tsunami. Journal of Geophysical Research: Oceans. doi: 10.1002/2016JC011742

Persistent Identifiers for Field Deployments: A Missing Link in the Provenance Chain

NASA Astrophysics Data System (ADS)

Arko, R. A.; Ji, P.; Fils, D.; Shepherd, A.; Chandler, C. L.; Lehnert, K.

2016-12-01

Research in the geosciences is characterized by a wide range of complex and costly field deployments including oceanographic cruises, submersible dives, drilling expeditions, seismic networks, geodetic campaigns, moored arrays, aircraft flights, and satellite missions. Each deployment typically produces a mix of sensor and sample data, spanning a period from hours to decades, that ultimately yields a long tail of post-field products and publications. Publishing persistent, citable identifiers for field deployments will facilitate 1) preservation and reuse of the original field data, 2) reproducibility of the resulting publications, and 3) recognition for both the facilities that operate the platforms and the investigators who secure funding for the experiments. In the ocean domain, sharing unique identifiers for field deployments is a familiar practice. For example, the Biological and Chemical Oceanography Data Management Office (BCO-DMO) routinely links datasets to cruise identifiers published by the Rolling Deck to Repository (R2R) program. In recent years, facilities have started to publish formal/persistent identifiers, typically Digital Object Identifiers (DOIs), for field deployments including seismic networks, oceanographic cruises, and moored arrays. For example, the EarthChem Library (ECL) publishes a DOI for each dataset which, if it derived from an oceanographic research cruise on a US vessel, is linked to a DOI for the cruise published by R2R. Work is underway to create similar links for the IODP JOIDES Resolution Science Operator (JRSO) and the Continental Scientific Drilling Coordination Office (CSDCO). We present results and lessons learned including a draft schema for publishing field deployments as DataCite DOI records; current practice for linking these DOIs with related identifiers such as Open Researcher and Contributor IDs (ORCIDs), Open Funder Registry (OFR) codes, and International Geo Sample Numbers (IGSNs); and consideration of other

20 Years of persistent identifiers - Which systems are here to stay?

NASA Astrophysics Data System (ADS)

Klump, Jens; Huber, Robert; Lehnert, Kerstin

2016-04-01

Web-based persistent identifiers have been around for more than 20 years, a period long enough to start observing patterns of success and failure. Persistent identifiers were invented to address challenges arising from the distributed and disorganised nature of the internet, which not only allowed new technologies to emerge, it also made it difficult to maintain a persistent record of science. Persistent identifiers now allow unambiguous identification of resources on the net. The expectations were that persistent identifiers would lead to greater accessibility, transparency and reproducibility of research results. Over the past two decades a number of persistent identifier systems have been built, one of them being Digital Object Identifiers (DOI). While DOI were originally invented by the publishing industry, they quickly became an established way for the identification of research resources. At first, these resources referred to scholarly literature and related resources. Other identifier systems, some of them using DOI as an example, were developed as grass-roots efforts by the scientific community. The concept of using persistent identifiers has since been expanded to other, non-textual resources, like datasets (DOI, EPIC) and geological specimens (IGSN), and more recently to authors and contributors of scholarly works (ORCID), and to software and instruments. A common witticism states that "a great thing about standards is that there are so many to choose from." Setting up identifier systems is technically trivial. The real challenge lies in creating a governance system for the respective identifiers. Which systems will stand the test of time? Drawing on data from the Registry of Research Data Repositories (re3data.org) and our own experience in the field, this presentation looks at the history and adoption of existing identifier systems and how this gives us some indications towards factors influencing sustainability of these systems.

Implementing DOIs for Oceanographic Satellite Data at PO.DAAC

NASA Astrophysics Data System (ADS)

Hausman, J.; Tauer, E.; Chung, N.; Chen, C.; Moroni, D. F.

2013-12-01

satellite and data center (or archive), but scientific writings do not typically provide enough detail to point to a singular, uniquely identifiable dataset. DOIs provide the means to help researchers be precise in their data citations and provide needed clarity, standardization and permanence.

Persistent Identifiers for Field Expeditions: A Next Step for the US Oceanographic Research Fleet

NASA Astrophysics Data System (ADS)

Arko, Robert; Carbotte, Suzanne; Chandler, Cynthia; Smith, Shawn; Stocks, Karen

2016-04-01

Oceanographic research cruises are complex affairs, typically requiring an extensive effort to secure the funding, plan the experiment, and mobilize the field party. Yet cruises are not typically published online as first-class digital objects with persistent, citable identifiers linked to the scientific literature. The Rolling Deck to Repository (R2R; info@rvdata.us) program maintains a master catalog of oceanographic cruises for the United States research fleet, currently documenting over 6,000 expeditions on 37 active and retired vessels. In 2015, R2R started routinely publishing a Digital Object Identifier (DOI) for each completed cruise. Cruise DOIs, in turn, are linked to related persistent identifiers where available including the Open Researcher and Contributor ID (ORCID) for members of the science party, the International Geo Sample Number (IGSN) for physical specimens collected during the cruise, the Open Funder Registry (FundRef) codes that supported the experiment, and additional DOIs for datasets, journal articles, and other products resulting from the cruise. Publishing a persistent identifier for each field expedition will facilitate interoperability between the many different repositories that hold research products from cruises; will provide credit to the investigators who secured the funding and carried out the experiment; and will facilitate the gathering of fleet-wide altmetrics that demonstrate the broad impact of oceanographic research.

RAPTOR-scan: Identifying and Tracking Objects Through Thousands of Sky Images

DOE Office of Scientific and Technical Information (OSTI.GOV)

Davidoff, Sherri; Wozniak, Przemyslaw

2004-09-28

The RAPTOR-scan system mines data for optical transients associated with gamma-ray bursts and is used to create a catalog for the RAPTOR telescope system. RAPTOR-scan can detect and track individual astronomical objects across data sets containing millions of observed points.Accurately identifying a real object over many optical images (clustering the individual appearances) is necessary in order to analyze object light curves. To achieve this, RAPTOR telescope observations are sent in real time to a database. Each morning, a program based on the DBSCAN algorithm clusters the observations and labels each one with an object identifier. Once clustering is complete, themore » analysis program may be used to query the database and produce light curves, maps of the sky field, or other informative displays.Although RAPTOR-scan was designed for the RAPTOR optical telescope system, it is a general tool designed to identify objects in a collection of astronomical data and facilitate quick data analysis. RAPTOR-scan will be released as free software under the GNU General Public License.« less

WISE Identified Young Stellar Objects In BRC 38

NASA Astrophysics Data System (ADS)

Gibbs, John; Rebull, L. M.; Laurence, W.; Marshall, R.; Murphy, M.; Orr, L.; Whitworth, C.; Burton, A.; Corris, T.; Goodey, S.; McGinnis, S.; Laurence, C.; Aschman, O.; Kikuchi, R.; Prather, J.; Whitley, L.; Billings, C.; Mader, C.

2014-01-01

Bright rimmed clouds (BRCs) are dense clumps of gas and dust within HII regions at the edges of molecular clouds; while the BRCs themselves are dark, their rims are optically bright from illumination by nearby O or B stars. Many BRCs show evidence of active star formation possibly triggered by the ionizing radiation from the nearby O or B stars. The large molecular cloud IC1396 is home to eleven BRCs thought to be driven by the O6.5V star HD206267. BRC 38 is located in the north of IC1396, at 21:40:42 +58:16:13. The immediate ~5'x5' region around BRC 38 has been extensively studied in many wavelengths from X-rays to infrared (IR), identifying ~100 young stellar objects (YSOs). We used data from the Wide-field Infrared Survey Explorer (WISE) to expand the search for YSOs to a 20 arcminute radius from the center of BRC 38. Starting with approximately 7000 sources identified in the WISE catalog, we used an updated version of the IR color selection scheme developed by Koenig et al. (2012) to identify ~40 objects having IR colors consistent with those of YSOs; some overlapping with the literature YSO candidates. Combining confirmed and candidate YSOs from literature with those we identified by color selection, we find 115 unique objects of interest. For each of these sources, we analyzed (a) the WISE, 2MASS, and Spitzer images to determine if they were point-like sources; (b) their IR colors to determine if they exhibited a clear IR excess; and (c) their spectral energy distributions (SEDs) to determine if they had an SED shape consistent with their identification as YSO candidates. Our work adds several new YSO candidates to the list of YSOs in and near BRC 38 and newly identifies IR excesses for many of the previously identified YSOs in the region. We looked for evidence of triggered star formation in BRC 38, but are limited in our conclusions by small-number statistics. Support is provided for this work by the NASA/IPAC Teacher Archive Research Program (NITARP

Using Java to generate globally unique identifiers for DICOM objects.

PubMed

Kamauu, Aaron W C; Duvall, Scott L; Avrin, David E

2009-03-01

Digital imaging and communication in medicine (DICOM) specifies that all DICOM objects have globally unique identifiers (UIDs). Creating these UIDs can be a difficult task due to the variety of techniques in use and the requirement to ensure global uniqueness. We present a simple technique of combining a root organization identifier, assigned descriptive identifiers, and JAVA generated unique identifiers to construct DICOM compliant UIDs.

Choice of crystal surface finishing for a dual-ended readout depth-of-interaction (DOI) detector.

PubMed

Fan, Peng; Ma, Tianyu; Wei, Qingyang; Yao, Rutao; Liu, Yaqiang; Wang, Shi

2016-02-07

The objective of this study was to choose the crystal surface finishing for a dual-ended readout (DER) DOI detector. Through Monte Carlo simulations and experimental studies, we evaluated 4 crystal surface finishing options as combinations of crystal surface polishing (diffuse or specular) and reflector (diffuse or specular) options on a DER detector. We also tested one linear and one logarithm DOI calculation algorithm. The figures of merit used were DOI resolution, DOI positioning error, and energy resolution. Both the simulation and experimental results show that (1) choosing a diffuse type in either surface polishing or reflector would improve DOI resolution but degrade energy resolution; (2) crystal surface finishing with a diffuse polishing combined with a specular reflector appears a favorable candidate with a good balance of DOI and energy resolution; and (3) the linear and logarithm DOI calculation algorithms show overall comparable DOI error, and the linear algorithm was better for photon interactions near the ends of the crystal while the logarithm algorithm was better near the center. These results provide useful guidance in DER DOI detector design in choosing the crystal surface finishing and DOI calculation methods.

Applications for unique identifiers in the geological sciences

NASA Astrophysics Data System (ADS)

Klump, J.; Lehnert, K. A.

2012-12-01

Even though geology has always been a generalist discipline in many parts, approaches towards questions about Earth's past have become increasingly interdisciplinary. At the same time, a wealth of samples has been collected, the resulting data have been stored in in disciplinary databases, the interpretations published in scientific literature. In the past these resources have existed alongside each other, semantically linked only by the knowledge of the researcher and his peers. One of the main drivers towards the inception of the world wide web was the ability to link scientific sources over the internet. The Uniform Resource Locator (URL) used to locate resources on the web soon turned out to be ephemeral in nature. A more reliable way of addressing objects was needed, a way of persistent identification to make digital objects, or digital representations of objects, part of the record of science. With their high degree of centralisation the scientific publishing houses were quick to implement and adopt a system for unique and persistent identification, the Digital Object Identifier (DOI) ®. At the same time other identifier systems exist alongside DOI, e.g. URN, ARK, handle ®, and others. There many uses for persistent identification in science, other than the identification of journal articles. DOI are already used for the identification of data, thus making data citable. There are several initiatives to assign identifiers to authors and institutions to allow unique identification. A recent development is the application of persistent identifiers for geological samples. As most data in the geosciences are derived from samples, it is crucial to be able to uniquely identify the samples from which a set of data were derived. Incomplete documentation of samples in publications, use of ambiguous sample names are major obstacles for synthesis studies and re-use of data. Access to samples for re-analysis and re-appraisal is limited due to the lack of a central

Optical Spectra of Four Objects Identified with Variable Radio Sources

NASA Astrophysics Data System (ADS)

Chavushyan, V.; Mujica, R.; Gorshkov, A. G.; Konnikova, V. K.; Mingaliev, M. G.

2000-06-01

We obtained optical spectra of four objects identified with variable radio sources. Three objects (0029+0554, 0400+0550, 2245+0500) were found to be quasars with redshifts of 1.314, 0.761, and 1.091. One object (2349+0534) has a continuum spectrum characteristic of BL Lac objects. We analyze spectra of the radio sources in the range 0.97-21.7 GHz for the epoch 1997 and in the range 3.9-11.1 GHz for the epoch 1990, as well as the pattern of variability of their flux densities on time scales of 1.5 and 7 years.

Concept for Future Data Services at the Long-Term Archive of WDCC combining DOIs with common PIDs

NASA Astrophysics Data System (ADS)

Stockhause, Martina; Weigel, Tobias; Toussaint, Frank; Höck, Heinke; Thiemann, Hannes; Lautenschlager, Michael

2013-04-01

The World Data Center for Climate (WDCC) hosted at the German Climate Computing Center (DKRZ) maintains a long-term archive (LTA) of climate model data as well as observational data. WDCC distinguishes between two types of LTA data: Structured data: Data output of an instrument or of a climate model run consists of numerous, highly structured individual datasets in a uniform format. Part of these data is also published on an ESGF (Earth System Grid Federation) data node. Detailed metadata is available allowing for fine-grained user-defined data access. Unstructured data: LTA data of finished scientific projects are in general unstructured and consist of datasets of different formats, different sizes, and different contents. For these data compact metadata is available as content information. The structured data is suitable for WDCC's DataCite DOI process, the project data only in exceptional cases. The DOI process includes a thorough quality control process of technical as well as scientific aspects by the publication agent and the data creator. DOIs are assigned to data collections appropriate to be cited in scientific publications, like a simulation run. The data collection is defined in agreement with the data creator. At the moment there is no possibility to identify and cite individual datasets within this DOI data collection analogous to the citation of chapters in a book. Also missing is a compact citation regulation for a user-specified collection of data. WDCC therefore complements its existing LTA/DOI concept by Persistent Identifier (PID) assignment to datasets using Handles. In addition to data identification for internal and external use, the concept of PIDs allows to define relations among PIDs. Such structural information is stored as key-value pair directly in the handles. Thus, relations provide basic provenance or lineage information, even if part of the data like intermediate results are lost. WDCC intends to use additional PIDs on metadata

Components of action representations evoked when identifying manipulable objects

PubMed Central

Bub, Daniel N.; Masson, Michael E. J.; Lin, Terry

2015-01-01

We examined the influence of holding planned hand actions in working memory on the time taken to visually identify objects with handles. Features of the hand actions and position of the object's handle were congruent or incongruent on two dimensions: alignment (left vs. right) and orientation (horizontal vs. vertical). When an object was depicted in an upright view, subjects were slower to name it when its handle was congruent with the planned hand actions on one dimension but incongruent on the other, relative to when the object handle and actions were congruent on both or neither dimension. This pattern is consistent with many other experiments demonstrating that a cost occurs when there is partial feature overlap between a planned action and a perceived target. An opposite pattern of results was obtained when the depicted object appeared in a 90° rotated view (e.g., a beer mug on its side), suggesting that the functional goal associated with the object (e.g., drinking from an upright beer mug) was taken into account during object perception and that this knowledge superseded the influence of the action afforded by the depicted view of the object. These results have implications for the relationship between object perception and action representations, and for the mechanisms that support the identification of rotated objects. PMID:25705187

Identifying the location of a concealed object through unintentional eye movements

PubMed Central

Neuman, Yair; Assaf, Dan; Israeli, Navot

2015-01-01

In some investigative and interrogative contexts, the investigator is seeking to identify the location of an object (e.g., implanted bomb) which is known to a given subject (e.g., a terrorist). In this paper, we present a non-intrusive methodology for uncovering the loci of a concealed object by analyzing the subject's eye movements. Using a combination of eye tracking, psychological manipulation and a search algorithm, we have performed two experiments. In the first experiment, we have gained 58% hit rate in identifying the location of the concealed object and in the second experiment 56% hit rate. The pros and cons of the methodology for forensic investigation are discussed. PMID:25904879

What is the Value Proposition of Persistent Identifiers?

NASA Astrophysics Data System (ADS)

Klump, Jens; Huber, Robert

2017-04-01

Persistent identifiers (PID) are widely used today in scientific communication and documentation. Global unique identification plus persistent resolution of links to referenced digital research objects have been strong selling points for PID Systems as enabling technical infrastructures. Novel applications of PID Systems in research now go beyond the identification of file based objects such as literature or data sets and include the identification of dynamically changing datasets accessed through web services, physical objects, persons and organisations. But not only do we see more use cases but also a proliferation of identifier systems. An analysis of PID Systems used by 1381 repositories listed in the Registry of Research Data Repositories (re3data.org, status of 14 Dec 2015) showed that many disciplinary data repositories make use of PID that are not among the systems promoted by the libraries and publishers (DOI, PURL, ARK). This indicates that a number of communities have developed their own PID Systems. This begs the question, do we need more identifier systems? What makes their value proposition more appealing than those of already existing systems? On the other hand, some of these new use cases deal with entities outside the digital domain, the original scope of application for PIDs. It is therefore necessary to critically appraise the value propositions of available PID Systems and compare these against the requirements of new use cases for PID. Undoubtedly, DOI are the most used persistent identifier in scholarly communication. It was originally designed "to link customers with publishers, facilitate electronic commerce, and enable copyright management systems." Today, the DOI system is described as providing "a technical and social infrastructure for the registration and use of persistent interoperable identifiers for use on digital networks". This example shows how value propositions can change over time. Additional value can be gained by cross

Amae as metalanguage: a critique of Doi's theory of amae.

PubMed

Taketomo, Y

1986-10-01

For many years Doi's ideas on the links between amae and the satisfaction of dependency needs have influenced discussions of the so-called Japanese character. In reviewing Doi's theory, however, major problems emerge. Beginning with the very definition of amae, one finds that Doi has chosen to stress only one aspect of amae. When one returns to his lexical sources, one discovers that the common denominator in the various definitions of amae does not lie in a single, monolithic motivation, as Doi proposes. Instead, it is suggested, amae should be viewed as a metalanguage. To understand the metacommunicational significance of amae, one must consider the rules that govern the behavior of the interactants in amae. Three different situations of amae are delineated. In the childhood interaction, the child playfully mimicks the infant's attachment behavior. With the adult coquetry situation, one observes the female playfully behaving as if she were the child mimicking the infant-mother prototype. Finally, in the third context subset of amae, there is a "trespassing on" or "taking advantage of" another person, with the beneficent approval of the second interactant. The common factor thus appears to be a mutually agreed-upon suspension of certain ordinary restraints on behavior. A metalanguage theory of amae, as an alternative to Doi's proposal, places emphasis on the culture-specific message of the interaction itself rather than on a single, monolithic motivation or an object-language interpretation. Indeed, various motivations are suggested, depending on the specific context of amae as well as the individual case. In this way, it is hoped, a metacommunicational approach to the understanding of amae may broaden the consideration of motivational issues, extending far beyond Doi's insistence on dependency and the search for passive love.

2 CFR 1401.330 - How and when must I identify workplaces?

Code of Federal Regulations, 2011 CFR

2011-01-01

... must identify all known workplaces under each DOI award. A failure to do so is a violation of your drug-free workplace requirements. You may identify the workplaces— (1) To the DOI official that is making... available for inspection upon request by DOI officials or their designated representatives. (b) Your...

Persistent Identifiers Implementation in EOSDIS

NASA Technical Reports Server (NTRS)

Ramapriyan, H. K. " Rama"

2016-01-01

This presentation provides the motivation for and status of implementation of persistent identifiers in NASA's Earth Observation System Data and Information System (EOSDIS). The motivation is provided from the point of view of long-term preservation of datasets such that a number of questions raised by current and future users can be answered easily and precisely. A number of artifacts need to be preserved along with datasets to make this possible, especially when the authors of datasets are no longer available to address users questions. The artifacts and datasets need to be uniquely and persistently identified and linked with each other for full traceability, understandability and scientific reproducibility. Current work in the Earth Science Data and Information System (ESDIS) Project and the Distributed Active Archive Centers (DAACs) in assigning Digital Object Identifiers (DOI) is discussed as well as challenges that remain to be addressed in the future.

Evaluation of unique identifiers used as keys to match identical publications in Pure and SciVal - a case study from health science.

PubMed

Madsen, Heidi Holst; Madsen, Dicte; Gauffriau, Marianne

2016-01-01

Unique identifiers (UID) are seen as an effective key to match identical publications across databases or identify duplicates in a database. The objective of the present study is to investigate how well UIDs work as match keys in the integration between Pure and SciVal, based on a case with publications from the health sciences. We evaluate the matching process based on information about coverage, precision, and characteristics of publications matched versus not matched with UIDs as the match keys. We analyze this information to detect errors, if any, in the matching process. As an example we also briefly discuss how publication sets formed by using UIDs as the match keys may affect the bibliometric indicators number of publications, number of citations, and the average number of citations per publication.  The objective is addressed in a literature review and a case study. The literature review shows that only a few studies evaluate how well UIDs work as a match key. From the literature we identify four error types: Duplicate digital object identifiers (DOI), incorrect DOIs in reference lists and databases, DOIs not registered by the database where a bibliometric analysis is performed, and erroneous optical or special character recognition. The case study explores the use of UIDs in the integration between the databases Pure and SciVal. Specifically journal publications in English are matched between the two databases. We find all error types except erroneous optical or special character recognition in our publication sets. In particular the duplicate DOIs constitute a problem for the calculation of bibliometric indicators as both keeping the duplicates to improve the reliability of citation counts and deleting them to improve the reliability of publication counts will distort the calculation of average number of citations per publication. The use of UIDs as a match key in citation linking is implemented in many settings, and the availability of UIDs may become

Evaluation of unique identifiers used as keys to match identical publications in Pure and SciVal – a case study from health science

PubMed Central

Madsen, Heidi Holst; Madsen, Dicte; Gauffriau, Marianne

2016-01-01

Unique identifiers (UID) are seen as an effective key to match identical publications across databases or identify duplicates in a database. The objective of the present study is to investigate how well UIDs work as match keys in the integration between Pure and SciVal, based on a case with publications from the health sciences. We evaluate the matching process based on information about coverage, precision, and characteristics of publications matched versus not matched with UIDs as the match keys. We analyze this information to detect errors, if any, in the matching process. As an example we also briefly discuss how publication sets formed by using UIDs as the match keys may affect the bibliometric indicators number of publications, number of citations, and the average number of citations per publication.  The objective is addressed in a literature review and a case study. The literature review shows that only a few studies evaluate how well UIDs work as a match key. From the literature we identify four error types: Duplicate digital object identifiers (DOI), incorrect DOIs in reference lists and databases, DOIs not registered by the database where a bibliometric analysis is performed, and erroneous optical or special character recognition. The case study explores the use of UIDs in the integration between the databases Pure and SciVal. Specifically journal publications in English are matched between the two databases. We find all error types except erroneous optical or special character recognition in our publication sets. In particular the duplicate DOIs constitute a problem for the calculation of bibliometric indicators as both keeping the duplicates to improve the reliability of citation counts and deleting them to improve the reliability of publication counts will distort the calculation of average number of citations per publication. The use of UIDs as a match key in citation linking is implemented in many settings, and the availability of UIDs may become

Isolation of 2-deoxy-scyllo-inosose (DOI)-assimilating yeasts and cloning and characterization of the DOI reductase gene of Cryptococcus podzolicus ND1.

PubMed

Ara, Satoshi; Yamazaki, Harutake; Takaku, Hiroaki

2018-04-01

2-Deoxy-scyllo-inosose (DOI) is the first intermediate in the 2-deoxystreptamine-containing aminoglycoside antibiotic biosynthesis pathway and has a six-membered carbocycle structure. DOI is a valuable material because it is easily converted to aromatic compounds and carbasugar derivatives. In this study, we isolated yeast strains capable of assimilating DOI as a carbon source. One of the strains, Cryptococcus podzolicus ND1, mainly converted DOI to scyllo-quercitol and (-)-vibo-quercitol, which is a valuable compound used as an antihypoglycemia agent and as a heat storage material. An NADH-dependent DOI reductase coding gene, DOIR, from C. podzolicus ND1 was cloned and successfully overexpressed in Escherichia coli. The purified protein catalyzed the irreversible reduction of DOI with NADH and converted DOI into (-)-vibo-quercitol. The enzyme had an optimal pH of 8.5 and optimal temperature of 35°C, respectively. The k cat of this enzyme was 9.98 s -1 , and the K m values for DOI and NADH were 4.38 and 0.24 mM, respectively. The enzyme showed a strong preference for NADH and showed no activity with NADPH. Multiple-alignment analysis of DOI reductase revealed that it belongs to the GFO_IDH_MocA protein family and is an inositol dehydrogenase homolog in other fungi, such as Cryptococcus gattii, and bacteria, such as Bacillus subtilis. This is the first identification of a DOI-assimilating yeast and a gene involved in DOI metabolism in fungi. Copyright © 2017 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

PIDs for digital content: Are they used as they should be? The example of DOI and ORCID, told from a research library perspective

NASA Astrophysics Data System (ADS)

Kraft, Angelina; Dreyer, Britta; Löwe, Peter

2017-04-01

For finding, linking and citing research content, persistent digital identifiers are the key, as a persistent identifier is a long-lasting reference to a resource. But are PIDs really used as they should be? With respect to the obstacles of the PID systems, we face a diverse landscape of stakeholders, legacy systems, competing interests and often incomprehensible messaging filled with technical jargon around PIDs. Insufficient metadata quality is another major challenge for these systems. While the principal task for service providers lies in collaborating to provide a shared and easy to use PID infrastructure, it is the key responsibility for data centers to provide rich metadata and structured access to research content. Especially metadata and structured access are imperative for the most basic services such as search, citation tracking and reuse. And of course all needs to be human- and machine interoperable, as we want our machines to be able to interpret PIDs depended on a specific use case. Since 2004, the German National Library of Science and Technology (TIB) has been providing DOI services to data centers in Germany. Recent developments make clear that requirements for PIDs have changed. Science has developed a need for PIDs at multiple content levels: In addition to DOIs for journal articles and research data, PIDs for people, physical objects, collections, software, funders, organizations, expeditions, resources, instruments and even for data management plans are required to enable different platforms to exchange information consistently and unambiguously. In this work we want to emphasize on the distinct increases of total DOI registrations for research data and other research output such as images, videos or software in Germany within the past decade and how research institutes and universities differ in their DOI registration workflows. We present use cases which illustrate the deployment of DOIs e.g. for dynamic data, and demonstrate the need of

Performance evaluation for 120 four-layer DOI block detectors of the jPET-D4.

PubMed

Inadama, Naoko; Murayama, Hideo; Ono, Yusuke; Tsuda, Tomoaki; Hamamoto, Manabu; Yamaya, Taiga; Yoshida, Eiji; Shibuya, Kengo; Nishikido, Fumihiko; Takahashi, Kei; Kawai, Hideyuki

2008-01-01

The jPET-D4 is a brain positron emission tomography (PET) scanner that we have developed to meet user demands for high sensitivity and high spatial resolution. For this scanner, we developed a four-layer depth-of-interaction (DOI) detector. The four-layer DOI detector is a key component for the jPET-D4, its performance has great influence on the overall system performance. Previously, we reported the original technique for encoding four-layer DOI. Here, we introduce the final design of the jPET-D4 detector and present the results of an investigation on uniformity in performance of the detector. The performance evaluation was done over the 120 DOI crystal blocks for the detectors, which are to be assembled into the jPET-D4 scanner. We also introduce the crystal assembly method, which is simple enough, even though each DOI crystal block is composed of 1,024 crystal elements. The jPET-D4 detector consists of four layers of 16 x 16 Gd(2)SiO(5) (GSO) crystals and a 256-channel flat-panel position-sensitive photomultiplier tube (256ch FP-PMT). To identify scintillated crystals in the four-layer DOI detector, we use pulse shape discrimination and position discrimination on the two-dimensional (2D) position histogram. For pulse shape discrimination, two kinds of GSO crystals that show different scintillation decay time constants are used in the upper two and lower two layers, respectively. Proper reflector arrangement in the crystal block then allows the scintillated crystals to be identified in these two-layer groupings with two 2D position histograms. We produced the 120 DOI crystal blocks for the jPET-D4 system, and measured their characteristics such as the accuracy of pulse shape discrimination, energy resolution, and the pulse height of the full energy peak. The results show a satisfactory and uniform performance of the four-layer DOI crystal blocks; for example, misidentification rate in each GSO layer is <5% based on pulse shape discrimination, the averaged energy

Did Oligocene crustal thickening precede basin development in northern Thailand? A geochronological reassessment of Doi Inthanon and Doi Suthep

NASA Astrophysics Data System (ADS)

Gardiner, Nicholas J.; Roberts, Nick M. W.; Morley, Christopher K.; Searle, Michael P.; Whitehouse, Martin J.

2016-01-01

The Doi Inthanon and Doi Suthep metamorphic core complexes in northern Thailand are comprised of amphibolite-grade migmatitic gneisses mantled by lower-grade mylonites and metasedimentary sequences, thought to represent Cordilleran-style core complexes exhumed through the mobilization of a low-angle detachment fault. Previous studies have interpreted two metamorphic events (Late Triassic and Late Cretaceous), followed by ductile extension between the late Eocene and late Oligocene, a model which infers movement on the detachment at ca. 40 Ma, and which culminates in a rapid unroofing of the complexes in the early Miocene. The Chiang Mai Basin, the largest such Cenozoic Basin in the region, lies immediately to the east. Its development is related to the extension observed at Doi Inthanon and Doi Suthep, however it is not definitively dated, and models for its development have difficulty reconciling Miocene cooling ages with Eocene detachment movement. Here we present new in-situ LA-ICP-MS and SIMS U-Pb age data of zircon and monazite grains from gneiss and leucogranite samples taken from Doi Inthanon and Doi Suthep. Our new zircon data exhibit an older age range of 221-210 Ma, with younger ages of ca. 72 Ma, and 32-26 Ma. Our monazite data imply an older age cluster at 83-67 Ma, and a younger age cluster of 34-24 Ma. While our data support the view of Indosinian basement being reworked in the Cretaceous, they also indicate a late Eocene-Oligocene tectonothermal event, resulting in prograde metamorphism and anatexis. We suggest that this later event is related to localized transpressional thickening associated with sinistral movement on the Mae Ping Fault, coupled with thickening at the restraining bend of the Mae Yuan Fault to the immediate west of Doi Inthanon. Further, this upper Oligocene age limit from our zircon and monazite data would imply a younger Miocene constraint on movement of the detachment, which, when combined with the previously recorded Miocene

43 CFR 17.314 - Age distinctions contained in DOI regulations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Age distinctions contained in DOI... Age Standards for Determining Age Discrimination § 17.314 Age distinctions contained in DOI regulations. Any age distinctions contained in a rule or regulation issued by DOI shall be presumed to be...

43 CFR 17.314 - Age distinctions contained in DOI regulations.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 43 Public Lands: Interior 1 2013-10-01 2013-10-01 false Age distinctions contained in DOI... Age Standards for Determining Age Discrimination § 17.314 Age distinctions contained in DOI regulations. Any age distinctions contained in a rule or regulation issued by DOI shall be presumed to be...

43 CFR 17.314 - Age distinctions contained in DOI regulations.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 43 Public Lands: Interior 1 2014-10-01 2014-10-01 false Age distinctions contained in DOI... Age Standards for Determining Age Discrimination § 17.314 Age distinctions contained in DOI regulations. Any age distinctions contained in a rule or regulation issued by DOI shall be presumed to be...

43 CFR 17.314 - Age distinctions contained in DOI regulations.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true Age distinctions contained in DOI... Age Standards for Determining Age Discrimination § 17.314 Age distinctions contained in DOI regulations. Any age distinctions contained in a rule or regulation issued by DOI shall be presumed to be...

43 CFR 17.314 - Age distinctions contained in DOI regulations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Age distinctions contained in DOI... Age Standards for Determining Age Discrimination § 17.314 Age distinctions contained in DOI regulations. Any age distinctions contained in a rule or regulation issued by DOI shall be presumed to be...

STS-87 Mission Specialist Doi in white room

NASA Technical Reports Server (NTRS)

1997-01-01

STS-87 Mission Specialist Takao Doi, Ph.D., of the National Space Development Agency of Japan, is assisted with his ascent and re- entry flight suit by Dave Law, USA mechanical technician, in the white room at Launch Pad 39B as Dr. Doi prepares to enter the Space Shuttle orbiter Columbia on launch day. At right wearing glasses is Danny Wyatt, NASA quality assurance specialist. STS-87 is the fourth flight of the United States Microgravity Payload and Spartan-201. The 16-day mission will include a spacewalk by Dr. Doi and Mission Specialist Winston Scott.

Improvement of crystal identification performance for a four-layer DOI detector composed of crystals segmented by laser processing

NASA Astrophysics Data System (ADS)

Mohammadi, Akram; Inadama, Naoko; Yoshida, Eiji; Nishikido, Fumihiko; Shimizu, Keiji; Yamaya, Taiga

2017-09-01

We have developed a four-layer depth of interaction (DOI) detector with single-side photon readout, in which segmented crystals with the patterned reflector insertion are separately identified by the Anger-type calculation. Optical conditions between segmented crystals, where there is no reflector, affect crystal identification ability. Our objective of this work was to improve crystal identification performance of the four-layer DOI detector that uses crystals segmented with a recently developed laser processing technique to include laser processed boundaries (LPBs). The detector consisted of 2 × 2 × 4mm3 LYSO crystals and a 4 × 4 array multianode photomultiplier tube (PMT) with 4.5 mm anode pitch. The 2D position map of the detector was calculated by the Anger calculation method. At first, influence of optical condition on crystal identification was evaluated for a one-layer detector consisting of a 2 × 2 crystal array with three different optical conditions between the crystals: crystals stuck together using room temperature vulcanized (RTV) rubber, crystals with air coupling and segmented crystals with LPBs. The crystal array with LPBs gave the shortest distance between crystal responses in the 2D position map compared with the crystal array coupled with RTV rubber or air due to the great amount of cross-talk between segmented crystals with LPBs. These results were used to find optical conditions offering the optimum distance between crystal responses in the 2D position map for the four-layer DOI detector. Crystal identification performance for the four-layer DOI detector consisting of an 8 × 8 array of crystals segmented with LPBs was examined and it was not acceptable for the crystals in the first layer. The crystal identification was improved for the first layer by changing the optical conditions between all 2 × 2 crystal arrays of the first layer to RTV coupling. More improvement was observed by combining different optical conditions between all

Identifying Objects via Encased X-Ray-Fluorescent Materials - the Bar Code Inside

NASA Technical Reports Server (NTRS)

Schramm, Harry F.; Kaiser, Bruce

2005-01-01

Systems for identifying objects by means of x-ray fluorescence (XRF) of encased labeling elements have been developed. The XRF spectra of objects so labeled would be analogous to the external bar code labels now used to track objects in everyday commerce. In conjunction with computer-based tracking systems, databases, and labeling conventions, the XRF labels could be used in essentially the same manner as that of bar codes to track inventories and to record and process commercial transactions. In addition, as summarized briefly below, embedded XRF labels could be used to verify the authenticity of products, thereby helping to deter counterfeiting and fraud. A system, as described above, is called an encased core product identification and authentication system (ECPIAS). The ECPIAS concept is a modified version of that of a related recently initiated commercial development of handheld XRF spectral scanners that would identify alloys or detect labeling elements deposited on the surfaces of objects. In contrast, an ECPIAS would utilize labeling elements encased within the objects of interest. The basic ECPIAS concept is best illustrated by means of an example of one of several potential applications: labeling of cultured pearls by labeling the seed particles implanted in oysters to grow the pearls. Each pearl farmer would be assigned a unique mixture of labeling elements that could be distinguished from the corresponding mixtures of other farmers. The mixture would be either incorporated into or applied to the surfaces of the seed prior to implantation in the oyster. If necessary, the labeled seed would be further coated to make it nontoxic to the oyster. After implantation, the growth of layers of mother of pearl on the seed would encase the XRF labels, making these labels integral, permanent parts of the pearls that could not be removed without destroying the pearls themselves. The XRF labels would be read by use of XRF scanners, the spectral data outputs of which

Hyperspectral Technology Transfer to the US Department of Interior: Summary of Results of the NASA/DOI Hyperspectral Technology Transfer Project

NASA Technical Reports Server (NTRS)

Root, Ralph; Wickland, Diane

2001-01-01

In 1997 the Office of Biological Informatics and Outreach (OBIO), Biological Resources Division, US Geological Survey and NASA, Office of Earth Science (OES), initiated a coordinated effort for applying Airborne Visible and Infrared Imaging Spectrometer (AVIRIS) data and analysis, as a technology transfer project, to critical DOI environmental issues in four study sites throughout the United States. This work was accomplished by four US Department of the Interior (DOI) study teams with support from NASA/OES principal investigators and the Office of Earth Science programs. The studies, including personnel, objectives, background, project plans, and milestones were documented in a project website at . This report summarizes the final outcomes of the project, detailing accomplishments, lessons learned, and benefits realized to NASA, the US Geological Survey, and the participating DOI bureaus.

Characterization of stacked-crystal PET detector designs for measurement of both TOF and DOI.

PubMed

Schmall, Jeffrey P; Surti, Suleman; Karp, Joel S

2015-05-07

A PET detector with good timing resolution and two-level depth-of-interaction (DOI) discrimination can be constructed using a single-ended readout of scintillator stacks of Lanthanum Bromide (LaBr3), with various Cerium dopant concentrations, including pure Cerium Bromide (CeBr3). The stacked crystal geometry creates a unique signal shape for interactions occurring in each layer, which can be used to identify the DOI, while retaining the inherently good timing properties of LaBr3 and CeBr3. In this work, single pixel elements are used to optimize the choice of scintillator, coupling of layers, and type of photodetector, evaluating the performance using a fast, single-channel photomultiplier tube (PMT) and a single 4 × 4 mm(2) silicon photomultiplier (SiPM). We also introduce a method to quantify and evaluate the DOI discrimination accuracy. From signal shape measurements using fast waveform sampling, we found that in addition to differences in signal rise times, between crystal layers, there were also differences in the signal fall times. A DOI accuracy of 98% was achieved using our classification method for a stacked crystal pair, consisting of a 15 mm long LaBr3(Ce:20%) crystal on top of a 15 mm long CeBr3 crystal, readout using a PMT. A DOI accuracy of 95% was measured with a stack of two, identical, 12 mm long, CeBr3 crystals. The DOI accuracy of this crystal pair was reduced to 91% when using a SiPM for readout. For the stack of two, 12 mm long, CeBr3 crystals, a coincidence timing resolution (average of timing results from the top and bottom layer) of 199 ps was measured using a PMT, and this was improved to 153 ps when using a SiPM. These results show that with stacked LaBr3/CeBr3 scintillators and fast waveform sampling nearly perfect DOI accuracy can be achieved with excellent timing resolution-timing resolution that is only minimally degraded compared to results from a single CeBr3 crystal of comparable length to the stacked crystals. The

Characterization of stacked-crystal PET detector designs for measurement of both TOF and DOI

PubMed Central

Schmall, Jeffrey P; Surti, Suleman; Karp, Joel S

2015-01-01

A PET detector with good timing resolution and two-level depth-of-interaction (DOI) discrimination can be constructed using a single-ended readout of scintillator stacks of Lanthanum Bromide (LaBr3), with various Cerium dopant concentrations, including pure Cerium Bromide (CeBr3). The stacked crystal geometry creates a unique signal shape for interactions occurring in each layer, which can be used to identify the DOI, while retaining the inherently good timing properties of LaBr3 and CeBr3. In this work, single pixel elements are used to optimize the choice of scintillator, coupling of layers, and type of photodetector, evaluating the performance using a fast, single-channel photomultiplier tube (PMT) and a single 4×4 mm2 silicon photomultiplier (SiPM). We also introduce a method to quantify and evaluate the DOI discrimination accuracy. From signal shape measurements using fast waveform sampling, we found that in addition to differences in signal rise times, between crystal layers, there were also differences in the signal fall times. A DOI accuracy of 98% was achieved using our classification method for a stacked crystal pair, consisting of a 15-mm long LaBr3(Ce:20%) crystal on top of a 15-mm long CeBr3 crystal, readout using a PMT. A DOI accuracy of 95% was measured with a stack of two, identical, 12-mm long, CeBr3 crystals. The DOI accuracy of this crystal pair was reduced to 91% when using a SiPM for readout. For the stack of two, 12-mm long, CeBr3 crystals, a coincidence timing resolution (average of timing results from the top and bottom layer) of 199 ps was measured using a PMT, and this was improved to 153 ps when using a SiPM. These results show that with stacked LaBr3/CeBr3 scintillators and fast waveform sampling nearly perfect DOI accuracy can be achieved with excellent timing resolution—timing resolution that is only minimally degraded compared to results from a single CeBr3 crystal of comparable length to the stacked crystals. The interface in the

STS-87 Mission Specialist Takao Doi during CEIT

NASA Technical Reports Server (NTRS)

1997-01-01

STS-87 Mission Specialist Takao Doi , Ph.D., of the National Space Development Agency of Japan, participates in the Crew Equipment Integration Test (CEIT) in Kennedy Space Centers (KSC's) Vertical Processing Facility. Glenda Laws, the extravehicular activity (EVA) coordinator, Johnson Space Center, stands behind Dr. Doi. The CEIT gives astronauts an opportunity to get a hands-on look at the payloads with which they will be working on-orbit. STS-87 will be the fourth United States Microgravity Payload and flight of the Spartan-201 deployable satellite. During the mission, Dr. Doi will be the first Japanese astronaut to perform a spacewalk. STS-87 is scheduled for a Nov. 19 liftoff from KSC.

Emergence of transformation-tolerant representations of visual objects in rat lateral extrastriate cortex

PubMed Central

Tafazoli, Sina; Safaai, Houman; De Franceschi, Gioia; Rosselli, Federica Bianca; Vanzella, Walter; Riggi, Margherita; Buffolo, Federica; Panzeri, Stefano; Zoccolan, Davide

2017-01-01

Rodents are emerging as increasingly popular models of visual functions. Yet, evidence that rodent visual cortex is capable of advanced visual processing, such as object recognition, is limited. Here we investigate how neurons located along the progression of extrastriate areas that, in the rat brain, run laterally to primary visual cortex, encode object information. We found a progressive functional specialization of neural responses along these areas, with: (1) a sharp reduction of the amount of low-level, energy-related visual information encoded by neuronal firing; and (2) a substantial increase in the ability of both single neurons and neuronal populations to support discrimination of visual objects under identity-preserving transformations (e.g., position and size changes). These findings strongly argue for the existence of a rat object-processing pathway, and point to the rodents as promising models to dissect the neuronal circuitry underlying transformation-tolerant recognition of visual objects. DOI: http://dx.doi.org/10.7554/eLife.22794.001 PMID:28395730

Identifying Accessible Near-Earth Objects For Crewed Missions With Solar Electric Propulsion

NASA Technical Reports Server (NTRS)

Smet, Stijn De; Parker, Jeffrey S.; Herman, Jonathan F. C.; Aziz, Jonathan; Barbee, Brent W.; Englander, Jacob A.

2015-01-01

This paper discusses the expansion of the Near-Earth Object Human Space Flight Accessible Targets Study (NHATS) with Solar Electric Propulsion (SEP). The research investigates the existence of new launch seasons that would have been impossible to achieve using only chemical propulsion. Furthermore, this paper shows that SEP can be used to significantly reduce the launch mass and in some cases the flight time of potential missions as compared to the current, purely chemical trajectories identified by the NHATS project.

Long-Term Repetition Priming of Briefly Identified Objects

ERIC Educational Resources Information Center

Breuer, Andreas T.; Masson, Michael E. J.; Cohen, Anna-Lisa; Lindsay, D. Stephen

2009-01-01

The authors provide evidence that long-term memory encoding can occur for briefly viewed objects in a rapid serial visual presentation list, contrary to claims that the brief presentation and quick succession of objects prevent encoding by disrupting a memory consolidation process that requires hundreds of milliseconds of uninterrupted processing.…

30 CFR 250.1005 - Inspection requirements for DOI pipelines.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Inspection requirements for DOI pipelines. 250.1005 Section 250.1005 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR...-Way § 250.1005 Inspection requirements for DOI pipelines. (a) Pipeline routes shall be inspected at...

30 CFR 250.1005 - Inspection requirements for DOI pipelines.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Inspection requirements for DOI pipelines. 250.1005 Section 250.1005 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT... Pipelines and Pipeline Rights-of-Way § 250.1005 Inspection requirements for DOI pipelines. (a) Pipeline...

Identifying and structuring the objectives of terrorists.

PubMed

Keeney, Gregory L; Von Winterfeldt, Detlof

2010-12-01

The risk of terrorism is of great concern to many countries and significant resources are spent to counter this threat. A better understanding of the motivation of terrorists and their reasons for selecting certain modes and targets of attack can help improve the decisions to allocate resources in the fight against terrorism. The fundamental question addressed in this article is: "What do terrorists want?" We take the view that terrorists' preferences for actions are based on their values and beliefs. An important missing piece in our knowledge of terrorists' preferences is an understanding of their values. This article uses a novel approach to determine these values and state them as objectives, using principles from decision analysis and value-focused thinking. Instead of interviewing decisionmakers and stakeholders, as would be normal in decision analysis, we extract the values of terrorists by examining their own writings and verbal statements. To illustrate the approach, we extract the values of Al-Qaeda and structure them in terms of strategic, fundamental, and means objectives. These objectives are interrelated through a means-ends network. This information is useful for understanding terrorists' motivations, intent, and likely actions, as well as for developing policies to counter terrorism at its root causes. © 2010 Society for Risk Analysis.

Persistent Identifiers, Discoverability and Open Science (Communication)

NASA Astrophysics Data System (ADS)

Murphy, Fiona; Lehnert, Kerstin; Hanson, Brooks

2016-04-01

Early in 2016, the American Geophysical Union announced it was incorporating ORCIDs into its submission workflows. This was accompanied by a strong statement supporting the use of other persistent identifiers - such as IGSNs, and the CrossRef open registry 'funding data'. This was partly in response to funders' desire to track and manage their outputs. However the more compelling argument, and the reason why the AGU has also signed up to the Center for Open Science's Transparency and Openness Promotion (TOP) Guidelines (http://cos.io/top), is that ultimately science and scientists will be the richer for these initiatives due to increased opportunities for interoperability, reproduceability and accreditation. The AGU has appealed to the wider community to engage with these initiatives, recognising that - unlike the introduction of Digital Object Identifiers (DOIs) for articles by CrossRef - full, enriched use of persistent identifiers throughout the scientific process requires buy-in from a range of scholarly communications stakeholders. At the same time, across the general research landscape, initiatives such as Project CRediT (contributor roles taxonomy), Publons (reviewer acknowledgements) and the forthcoming CrossRef DOI Event Tracker are contributing to our understanding and accreditation of contributions and impact. More specifically for earth science and scientists, the cross-functional Coalition for Publishing Data in the Earth and Space Sciences (COPDESS) was formed in October 2014 and is working to 'provide an organizational framework for Earth and space science publishers and data facilities to jointly implement and promote common policies and procedures for the publication and citation of data across Earth Science journals'. Clearly, the judicious integration of standards, registries and persistent identifiers such as ORCIDs and International Geo Sample Numbers (IGSNs) to the research and research output processes is key to the success of this venture

43 CFR 2.31 - How will DOI respond to my appeal?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false How will DOI respond to my appeal? 2.31... OF INFORMATION ACT FOIA Appeals § 2.31 How will DOI respond to my appeal? (a) Appeals will be decided... will state the basis for DOI's decision as follows: (1) Decision to release or withhold records. (i) If...

43 CFR 2.31 - How will DOI respond to my appeal?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false How will DOI respond to my appeal? 2.31... OF INFORMATION ACT FOIA Appeals § 2.31 How will DOI respond to my appeal? (a) Appeals will be decided... will state the basis for DOI's decision as follows: (1) Decision to release or withhold records. (i) If...

Identifying online user reputation of user-object bipartite networks

NASA Astrophysics Data System (ADS)

Liu, Xiao-Lu; Liu, Jian-Guo; Yang, Kai; Guo, Qiang; Han, Jing-Ti

2017-02-01

Identifying online user reputation based on the rating information of the user-object bipartite networks is important for understanding online user collective behaviors. Based on the Bayesian analysis, we present a parameter-free algorithm for ranking online user reputation, where the user reputation is calculated based on the probability that their ratings are consistent with the main part of all user opinions. The experimental results show that the AUC values of the presented algorithm could reach 0.8929 and 0.8483 for the MovieLens and Netflix data sets, respectively, which is better than the results generated by the CR and IARR methods. Furthermore, the experimental results for different user groups indicate that the presented algorithm outperforms the iterative ranking methods in both ranking accuracy and computation complexity. Moreover, the results for the synthetic networks show that the computation complexity of the presented algorithm is a linear function of the network size, which suggests that the presented algorithm is very effective and efficient for the large scale dynamic online systems.

Carbon-free production of 2-deoxy-scyllo-inosose (DOI) in cyanobacterium Synechococcus elongatus PCC 7942.

PubMed

Watanabe, Satoru; Ozawa, Hiroaki; Kato, Hiroaki; Nimura-Matsune, Kaori; Hirayama, Toshifumi; Kudo, Fumitaka; Eguchi, Tadashi; Kakinuma, Katsumi; Yoshikawa, Hirofumi

2018-01-01

Owing to their photosynthetic capabilities, there is increasing interest in utilizing cyanobacteria to convert solar energy into biomass. 2-Deoxy-scyllo-inosose (DOI) is a valuable starting material for the benzene-free synthesis of catechol and other benzenoids. DOI synthase (DOIS) is responsible for the formation of DOI from d-glucose-6-phosphate (G6P) in the biosynthesis of 2-deoxystreptamine-containing aminoglycoside antibiotics such as neomycin and butirosin. DOI fermentation using a recombinant Escherichia coli strain has been reported, although a carbon source is necessary for high-yield DOI production. We constructed DOI-producing cyanobacteria toward carbon-free and sustainable DOI production. A DOIS gene derived from the butirosin producer strain Bacillus circulans (btrC) was introduced and expressed in the cyanobacterium Synechococcus elongatus PCC 7942. We ultimately succeeded in producing 400 mg/L of DOI in S. elongatus without using a carbon source. DOI production by cyanobacteria represents a novel and efficient approach for producing benzenoids from G6P synthesized by photosynthesis.

Manganese-enhanced magnetic resonance imaging reveals increased DOI-induced brain activity in a mouse model of schizophrenia

PubMed Central

Malkova, Natalia V.; Gallagher, Joseph J.; Yu, Collin Z.; Jacobs, Russell E.; Patterson, Paul H.

2014-01-01

Maternal infection during pregnancy increases the risk for schizophrenia in offspring. In rodent models, maternal immune activation (MIA) yields offspring with schizophrenia-like behaviors. None of these behaviors are, however, specific to schizophrenia. The presence of hallucinations is a key diagnostic symptom of schizophrenia. In mice, this symptom can be defined as brain activation in the absence of external stimuli, which can be mimicked by administration of hallucinogens. We find that, compared with controls, adult MIA offspring display an increased stereotypical behavioral response to the hallucinogen 2,5-dimethoxy-4-iodoamphetamine (DOI), an agonist for serotonin receptor 2A (5-HT2AR). This may be explained by increased levels of 5-HT2AR and downstream signaling molecules in unstimulated MIA prefrontal cortex (PFC). Using manganese-enhanced magnetic resonance imaging to identify neuronal activation elicited by DOI administration, we find that, compared with controls, MIA offspring exhibit a greater manganese (Mn2+) accumulation in several brain areas, including the PFC, thalamus, and striatum. The parafascicular thalamic nucleus, which plays the role in the pathogenesis of hallucinations, is activated by DOI in MIA offspring only. Additionally, compared with controls, MIA offspring demonstrate higher DOI-induced expression of early growth response protein 1, cyclooxygenase-2, and brain-derived neurotrophic factor in the PFC. Chronic treatment with the 5-HT2AR antagonist ketanserin reduces DOI-induced head twitching in MIA offspring. Thus, the MIA mouse model can be successfully used to investigate activity induced by DOI in awake, behaving mice. Moreover, manganese-enhanced magnetic resonance imaging is a useful, noninvasive method for accurately measuring this type of activity. PMID:24889602

Manganese-enhanced magnetic resonance imaging reveals increased DOI-induced brain activity in a mouse model of schizophrenia.

PubMed

Malkova, Natalia V; Gallagher, Joseph J; Yu, Collin Z; Jacobs, Russell E; Patterson, Paul H

2014-06-17

Maternal infection during pregnancy increases the risk for schizophrenia in offspring. In rodent models, maternal immune activation (MIA) yields offspring with schizophrenia-like behaviors. None of these behaviors are, however, specific to schizophrenia. The presence of hallucinations is a key diagnostic symptom of schizophrenia. In mice, this symptom can be defined as brain activation in the absence of external stimuli, which can be mimicked by administration of hallucinogens. We find that, compared with controls, adult MIA offspring display an increased stereotypical behavioral response to the hallucinogen 2,5-dimethoxy-4-iodoamphetamine (DOI), an agonist for serotonin receptor 2A (5-HT2AR). This may be explained by increased levels of 5-HT2AR and downstream signaling molecules in unstimulated MIA prefrontal cortex (PFC). Using manganese-enhanced magnetic resonance imaging to identify neuronal activation elicited by DOI administration, we find that, compared with controls, MIA offspring exhibit a greater manganese (Mn(2+)) accumulation in several brain areas, including the PFC, thalamus, and striatum. The parafascicular thalamic nucleus, which plays the role in the pathogenesis of hallucinations, is activated by DOI in MIA offspring only. Additionally, compared with controls, MIA offspring demonstrate higher DOI-induced expression of early growth response protein 1, cyclooxygenase-2, and brain-derived neurotrophic factor in the PFC. Chronic treatment with the 5-HT2AR antagonist ketanserin reduces DOI-induced head twitching in MIA offspring. Thus, the MIA mouse model can be successfully used to investigate activity induced by DOI in awake, behaving mice. Moreover, manganese-enhanced magnetic resonance imaging is a useful, noninvasive method for accurately measuring this type of activity.

Featured Image: Identifying Weird Galaxies

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2017-08-01

Hoags Object, an example of a ring galaxy. [NASA/Hubble Heritage Team/Ray A. Lucas (STScI/AURA)]The above image (click for the full view) shows PanSTARRSobservationsof some of the 185 galaxies identified in a recent study as ring galaxies bizarre and rare irregular galaxies that exhibit stars and gas in a ring around a central nucleus. Ring galaxies could be formed in a number of ways; one theory is that some might form in a galaxy collision when a smaller galaxy punches through the center of a larger one, triggering star formation around the center. In a recent study, Ian Timmis and Lior Shamir of Lawrence Technological University in Michigan explore ways that we may be able to identify ring galaxies in the overwhelming number of images expected from large upcoming surveys. They develop a computer analysis method that automatically finds ring galaxy candidates based on their visual appearance, and they test their approach on the 3 million galaxy images from the first PanSTARRS data release. To see more of the remarkable galaxies the authors found and to learn more about their identification method, check out the paper below.CitationIan Timmis and Lior Shamir 2017 ApJS 231 2. doi:10.3847/1538-4365/aa78a3

A flood map based DOI decoding method for block detector: a GATE simulation study.

PubMed

Shi, Han; Du, Dong; Su, Zhihong; Peng, Qiyu

2014-01-01

Positron Emission Tomography (PET) systems using detectors with Depth of Interaction (DOI) capabilities could achieve higher spatial resolution and better image quality than those without DOI. Up till now, most DOI methods developed are not cost-efficient for a whole body PET system. In this paper, we present a DOI decoding method based on flood map for low-cost conventional block detector with four-PMT readout. Using this method, the DOI information can be directly extracted from the DOI-related crystal spot deformation in the flood map. GATE simulations are then carried out to validate the method, confirming a DOI sorting accuracy of 85.27%. Therefore, we conclude that this method has the potential to be applied in conventional detectors to achieve a reasonable DOI measurement without dramatically increasing their complexity and cost of an entire PET system.

Actionable, long-term stable and semantic web compatible identifiers for access to biological collection objects

PubMed Central

Hyam, Roger; Hagedorn, Gregor; Chagnoux, Simon; Röpert, Dominik; Casino, Ana; Droege, Gabi; Glöckler, Falko; Gödderz, Karsten; Groom, Quentin; Hoffmann, Jana; Holleman, Ayco; Kempa, Matúš; Koivula, Hanna; Marhold, Karol; Nicolson, Nicky; Smith, Vincent S.; Triebel, Dagmar

2017-01-01

With biodiversity research activities being increasingly shifted to the web, the need for a system of persistent and stable identifiers for physical collection objects becomes increasingly pressing. The Consortium of European Taxonomic Facilities agreed on a common system of HTTP-URI-based stable identifiers which is now rolled out to its member organizations. The system follows Linked Open Data principles and implements redirection mechanisms to human-readable and machine-readable representations of specimens facilitating seamless integration into the growing semantic web. The implementation of stable identifiers across collection organizations is supported with open source provider software scripts, best practices documentations and recommendations for RDF metadata elements facilitating harmonized access to collection information in web portals. Database URL: http://cetaf.org/cetaf-stable-identifiers PMID:28365724

43 CFR 45.25 - What will DOI do with any hearing requests?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false What will DOI do with any hearing requests... PRESCRIPTIONS IN FERC HYDROPOWER LICENSES Hearing Process Initiation of Hearing Process § 45.25 What will DOI do... will refer the case for a hearing as follows: (1) If the hearing is to be conducted by DOI, OEPC will...

43 CFR 45.25 - What will DOI do with any hearing requests?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false What will DOI do with any hearing requests... PRESCRIPTIONS IN FERC HYDROPOWER LICENSES Hearing Process Initiation of Hearing Process § 45.25 What will DOI do... will refer the case for a hearing as follows: (1) If the hearing is to be conducted by DOI, OEPC will...

Physical characterization of Warm Spitzer-observed near-Earth objects

NASA Astrophysics Data System (ADS)

Thomas, Cristina A.; Emery, Joshua P.; Trilling, David E.; Delbó, Marco; Hora, Joseph L.; Mueller, Michael

2014-01-01

Near-infrared spectroscopy of Near-Earth Objects (NEOs) connects diagnostic spectral features to specific surface mineralogies. The combination of spectroscopy with albedos and diameters derived from thermal infrared observations can increase the scientific return beyond that of the individual datasets. For instance, some taxonomic classes can be separated into distinct compositional groupings with albedo and different mineralogies with similar albedos can be distinguished with spectroscopy. To that end, we have completed a spectroscopic observing campaign to complement the ExploreNEOs Warm Spitzer program that obtained albedos and diameters of nearly 600 NEOs (Trilling, D.E. et al. [2010]. Astron. J. 140, 770-784. http://dx.doi.org/10.1088/0004-6256/140/3/770). The spectroscopy campaign included visible and near-infrared observations of ExploreNEOs targets from various observatories. Here we present the results of observations using the low-resolution prism mode (˜0.7-2.5 μm) of the SpeX instrument on the NASA Infrared Telescope Facility (IRTF). We also include near-infrared observations of ExploreNEOs targets from the MIT-UH-IRTF Joint Campaign for Spectral Reconnaissance. Our dataset includes near-infrared spectra of 187 ExploreNEOs targets (125 observations of 92 objects from our survey and 213 observations of 154 objects from the MIT survey). We identify a taxonomic class for each spectrum and use band parameter analysis to investigate the mineralogies for the S-, Q-, and V-complex objects. Our analysis suggests that for spectra that contain near-infrared data but lack the visible wavelength region, the Bus-DeMeo system misidentifies some S-types as Q-types. We find no correlation between spectral band parameters and ExploreNEOs albedos and diameters. We investigate the correlations of phase angle with Band Area Ratio and near-infrared spectral slope. We find slightly negative Band Area Ratio (BAR) correlations with phase angle for Eros and Ivar, but a

STS-87 Mission Specialist Takao Doi suits up

NASA Technical Reports Server (NTRS)

1997-01-01

STS-87 Mission Specialist Takao Doi, Ph.D., of the National Space Development Agency of Japan, gives a thumbs up in his launch and entry suit in the Operations and Checkout Building. He and the five other crew members will depart shortly for Launch Pad 39B, where the Space Shuttle Columbia awaits liftoff on a 16-day mission to perform microgravity and solar research. Dr. Doi is scheduled to perform an extravehicular activity spacewalk with Mission Specialist Winston Scott during STS-87.

Utilization of a cognitive task analysis for laparoscopic appendectomy to identify differentiated intraoperative teaching objectives.

PubMed

Smink, Douglas S; Peyre, Sarah E; Soybel, David I; Tavakkolizadeh, Ali; Vernon, Ashley H; Anastakis, Dimitri J

2012-04-01

Experts become automated when performing surgery, making it difficult to teach complex procedures to trainees. Cognitive task analysis (CTA) enables experts to articulate operative steps and cognitive decisions in complex procedures such as laparoscopic appendectomy, which can then be used to identify central teaching points. Three local surgeon experts in laparoscopic appendectomy were interviewed using critical decision method-based CTA methodology. Interview transcripts were analyzed, and a cognitive demands table (CDT) was created for each expert. The individual CDTs were reviewed by each expert for completeness and then combined into a master CDT. Percentage agreement on operative steps and decision points was calculated for each expert. The experts then participated in a consensus meeting to review the master CDT. Each surgeon expert was asked to identify in the master CDT the most important teaching objectives for junior-level and senior-level residents. The experts' responses for junior-level and senior-level residents were compared using a χ(2) test. The surgeon experts identified 24 operative steps and 27 decision points. Eighteen of the 24 operative steps (75%) were identified by all 3 surgeon experts. The percentage of operative steps identified was high for each surgeon expert (96% for surgeon 1, 79% for surgeon 2, and 83% for surgeon 3). Of the 27 decision points, only 5 (19%) were identified by all 3 surgeon experts. The percentage of decision points identified varied by surgeon expert (78% for surgeon 1, 59% for surgeon 2, and 48% for surgeon 3). When asked to identify key teaching points, the surgeon experts were more likely to identify operative steps for junior residents (9 operative steps and 6 decision points) and decision points for senior residents (4 operative steps and 13 decision points) (P < .01). CTA can deconstruct the essential operative steps and decision points associated with performing a laparoscopic appendectomy. These results

Identifying uncontrolled asthma in young children: clinical scores or objective variables?

PubMed

Leung, T F; Ko, F W S; Sy, H Y; Wong, E; Li, C Y; Yung, E; Hui, D S C; Wong, G W K; Lai, C K W

2009-03-01

Several international asthma guidelines emphasize the importance of assessing asthma control. However, there is limited data on the usefulness of available assessment tools in indicating disease control in young asthmatics. This study investigated the ability of Chinese version of Childhood Asthma Control Test (C-ACT) and other disease-related factors in identifying uncontrolled asthma (UA) in young children. During the same clinic visit, asthma patients 4 to 11 years of age completed C-ACT and underwent exhaled nitric oxide and spirometric measurements. Blinded to these results, the same investigator assigned Disease Severity Score (DSS) and rated asthma control according to Global Initiative for Asthma. The mean (SD) age of 113 recruited patients was 9.1 (2.0) years, and 35% of them had UA. C-ACT, DSS and forced expiratory volume in 1 second (FEV(1)) differed among patients with different control status (p < 0.001 for C-ACT and DSS; p = 0.014 for FEV(1)). Logistic regression confirmed that UA was associated with DSS (p < 0.001), PEF (p = 0.002), C-ACT (p = 0.011), and FEV(1) (p = 0.012). By ROC analysis, C-ACT and DSS were the best predictors for UA (p < 0.001), followed by PEF (p = 0.006) and FEV(1) (p = 0.007). When analyzed by the Classification and Regression Tree (CART) approach, the sequential use of DSS and C-ACT had 77% sensitivity and 84% specificity in identifying UA. C-ACT is better than objective parameters in identifying young Chinese children with UA.

In preparation of the nationwide dissemination of the school-based obesity prevention program DOiT: stepwise development applying the intervention mapping protocol.

PubMed

van Nassau, Femke; Singh, Amika S; van Mechelen, Willem; Brug, Johannes; Chin A Paw, Mai J M

2014-08-01

The school-based Dutch Obesity Intervention in Teenagers (DOiT) program is an evidence-based obesity prevention program. In preparation for dissemination throughout the Netherlands, this study aimed to adapt the initial program and to develop an implementation strategy and materials. We revisited the Intervention Mapping (IM) protocol, using results of the previous process evaluation and additional focus groups and interviews with students, parents, teachers, and professionals. The adapted 2-year DOiT program consists of a classroom, an environmental and a parental component. The year 1 lessons aim to increase awareness and knowledge of healthy behaviors. The lessons in year 2 focus on the influence of the (obesogenic) environment. The stepwise development of the implementation strategy resulted in objectives that support teachers' implementation. We developed a 7-step implementation strategy and supporting materials by translating the objectives into essential elements and practical strategies. This study illustrates how revisiting the IM protocol resulted in an adapted program and tailored implementation strategy based on previous evaluations as well as input from different stakeholders. The stepwise development of DOiT can serve as an example for other evidence-based programs in preparation for wider dissemination. Published 2014. This article is a U.S. Government work and is in the public domain in the USA.

Serial grouping of 2D-image regions with object-based attention in humans

PubMed Central

Jeurissen, Danique; Self, Matthew W; Roelfsema, Pieter R

2016-01-01

After an initial stage of local analysis within the retina and early visual pathways, the human visual system creates a structured representation of the visual scene by co-selecting image elements that are part of behaviorally relevant objects. The mechanisms underlying this perceptual organization process are only partially understood. We here investigate the time-course of perceptual grouping of two-dimensional image-regions by measuring the reaction times of human participants and report that it is associated with the gradual spread of object-based attention. Attention spreads fastest over large and homogeneous areas and is slowed down at locations that require small-scale processing. We find that the time-course of the object-based selection process is well explained by a 'growth-cone' model, which selects surface elements in an incremental, scale-dependent manner. We discuss how the visual cortical hierarchy can implement this scale-dependent spread of object-based attention, leveraging the different receptive field sizes in distinct cortical areas. DOI: http://dx.doi.org/10.7554/eLife.14320.001 PMID:27291188

Featured Image: Revealing Hidden Objects with Color

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2018-02-01

Stunning color astronomical images can often be the motivation for astronomers to continue slogging through countless data files, calculations, and simulations as we seek to understand the mysteries of the universe. But sometimes the stunning images can, themselves, be the source of scientific discovery. This is the case with the below image of Lynds Dark Nebula 673, located in the Aquila constellation, that was captured with the Mayall 4-meter telescope at Kitt Peak National Observatory by a team of scientists led by Travis Rector (University of Alaska Anchorage). After creating the image with a novel color-composite imaging method that reveals faint H emission (visible in red in both images here), Rector and collaborators identified the presence of a dozen new Herbig-Haro objects small cloud patches that are caused when material is energetically flung out from newly born stars. The image adapted above shows three of the new objects, HH 118789, aligned with two previously known objects, HH 32 and 332 suggesting they are driven by the same source. For more beautiful images and insight into the authors discoveries, check out the article linked below!Full view of Lynds Dark Nebula 673. Click for the larger view this beautiful composite image deserves! [T.A. Rector (University of Alaska Anchorage) and H. Schweiker (WIYN and NOAO/AURA/NSF)]CitationT. A. Rector et al 2018 ApJ 852 13. doi:10.3847/1538-4357/aa9ce1

Objective Model Selection for Identifying the Human Feedforward Response in Manual Control.

PubMed

Drop, Frank M; Pool, Daan M; van Paassen, Marinus Rene M; Mulder, Max; Bulthoff, Heinrich H

2018-01-01

Realistic manual control tasks typically involve predictable target signals and random disturbances. The human controller (HC) is hypothesized to use a feedforward control strategy for target-following, in addition to feedback control for disturbance-rejection. Little is known about human feedforward control, partly because common system identification methods have difficulty in identifying whether, and (if so) how, the HC applies a feedforward strategy. In this paper, an identification procedure is presented that aims at an objective model selection for identifying the human feedforward response, using linear time-invariant autoregressive with exogenous input models. A new model selection criterion is proposed to decide on the model order (number of parameters) and the presence of feedforward in addition to feedback. For a range of typical control tasks, it is shown by means of Monte Carlo computer simulations that the classical Bayesian information criterion (BIC) leads to selecting models that contain a feedforward path from data generated by a pure feedback model: "false-positive" feedforward detection. To eliminate these false-positives, the modified BIC includes an additional penalty on model complexity. The appropriate weighting is found through computer simulations with a hypothesized HC model prior to performing a tracking experiment. Experimental human-in-the-loop data will be considered in future work. With appropriate weighting, the method correctly identifies the HC dynamics in a wide range of control tasks, without false-positive results.

43 CFR 17.301 - What is the purpose of DOI's age discrimination regulations?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false What is the purpose of DOI's age... Age General § 17.301 What is the purpose of DOI's age discrimination regulations? The purpose of these regulations is to set out DOI's policies and procedures under the Age Discrimination Act of 1975 and the...

41 CFR 102-75.650 - When must DOI request assignment of the property?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false When must DOI request...-75.650 When must DOI request assignment of the property? Within 30 calendar days after the expiration of the 30-calendar day period specified in § 102-75.640, DOI must submit to the disposal agency an...

43 CFR 17.301 - What is the purpose of DOI's age discrimination regulations?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false What is the purpose of DOI's age... Age General § 17.301 What is the purpose of DOI's age discrimination regulations? The purpose of these regulations is to set out DOI's policies and procedures under the Age Discrimination Act of 1975 and the...

41 CFR 102-75.650 - When must DOI request assignment of the property?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false When must DOI request...-75.650 When must DOI request assignment of the property? Within 30 calendar days after the expiration of the 30-calendar day period specified in § 102-75.640, DOI must submit to the disposal agency an...

Featured Image: Identifying a Glowing Shell

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2018-05-01

New nebulae are being discovered and classified every day and this false-color image reveals one of the more recent objects of interest. This nebula, IPHASX J210204.7+471015, was recently imaged by the Andalucia Faint Object Spectrograph and Camera mounted on the 2.5-m Nordic Optical Telescope in La Palma, Spain. J210204 was initially identified as a possible planetary nebula a remnant left behind at the end of a red giants lifetime. Based on the above imaging, however, a team of authors led by Martn Guerrero (Institute of Astrophysics of Andalusia, Spain) is arguing that this shell of glowing gas was instead expelled around a classical nova. In a classical nova eruption, a white dwarf and its binary companion come very close together, and mass transfers to form a thin atmosphere of hydrogen around the white dwarf. When this hydrogen suddenly ignites in runaway fusion, this outer atmosphere can be expelled, forming a short-lived nova remnant which is what Guerrero and collaborators think were seeing with J210204. If so, this nebula can reveal information about the novathat caused it. To find out more about what the authors learned from this nebula, check out the paper below.CitationMartn A. Guerrero et al 2018 ApJ 857 80. doi:10.3847/1538-4357/aab669

Adopting ORCID as a unique identifier will benefit all involved in scholarly communication.

PubMed

Arunachalam, Subbiah; Madhan, Muthu

2016-01-01

ORCID, the Open Researcher and Contributor ID, is a non- profit, community-driven effort to create and maintain a registry of unique researcher identifiers and a transparent method of linking research activities and outputs to these identifiers. Together with other persistent identifiers for scholarly works such as digital object identifiers (DOIs) and identifiers for organizations, ORCID makes research more discoverable. It helps ensure that one's grants, publications and outputs are correctly attributed. It helps the research community not just in aggregating publications, but in every stage of research, viz. publishing, reviewing, profiling, metrics, accessing and archiving. Funding agencies in Austria, Australia, Denmark, Portugal, Sweden and the UK, and the world's leading scholarly publishers and associations have integrated their systems with ORCID registry. Among the BRICS countries, China and South Africa are adopting ORCID avidly. India is yet to make a beginning. If research councils and funding agencies in India require researchers to adopt ORCID and link ORCID iDs to funding as well as tracking performance, it will help them keep track of the workflow. Journal editors can also keep track of contributions made by different authors and work assigned to different reviewers through their ORCID iDs.

The hallucinogen DOI reduces low-frequency oscillations in rat prefrontal cortex: reversal by antipsychotic drugs.

PubMed

Celada, Pau; Puig, M Victoria; Díaz-Mataix, Llorenç; Artigas, Francesc

2008-09-01

Perceptual and psychic alterations and thought disorder are fundamental elements of schizophrenia symptoms, a pathology associated with an abnormal macro- and microcircuitry of several brain areas including the prefrontal cortex (PFC). Alterations in information processing in PFC may partly underlie schizophrenia symptoms. The 5-HT(2A/2C) agonist DOI and antipsychotic drugs were administered to anesthetized rats. Single unit and local field potential (LFP) extracellular recordings were made in medial PFC (mPFC). Electrolytic lesions were performed in the thalamic nuclei. DOI markedly disrupts cellular and network activity in rat PFC. DOI altered pyramidal discharge in mPFC (39% excited, 27% inhibited, 34% unaffected; n = 51). In all instances, DOI concurrently reduced low-frequency oscillations (.3-4 Hz; power spectrum: .25 +/- .02 and .14 +/- .01 microV(2) in basal conditions and after 50-300 microg/kg intravenous (i.v.) DOI, respectively; n = 51). Moreover, DOI disrupted the temporal association between the active phase of LFP and pyramidal discharge. Both effects were reversed by M100907 (5-HT(2A) receptor antagonist) and were not attenuated by thalamic lesions, supporting an intracortical origin of the effects of DOI. The reduction in low-frequency oscillations induced by DOI was significantly reversed by the antipsychotic drugs haloperidol (.1-.2 mg/kg i.v.) and clozapine (1 mg/kg i.v.). DOI disorganizes network activity in PFC, reducing low-frequency oscillations and desynchronizing pyramidal discharge from active phases of LFP. These effects may underlie DOI's psychotomimetic action. The reversal by clozapine and haloperidol indicates that antipsychotic drugs may reduce psychotic symptoms by normalizing an altered PFC function.

Toward Advancing Nano-Object Count Metrology: A Best Practice Framework

PubMed Central

Boyko, Volodymyr; Meyers, Greg; Voetz, Matthias; Wohlleben, Wendel

2013-01-01

Background: A movement among international agencies and policy makers to classify industrial materials by their number content of sub–100-nm particles could have broad implications for the development of sustainable nanotechnologies. Objectives: Here we highlight current particle size metrology challenges faced by the chemical industry due to these emerging number percent content thresholds, provide a suggested best-practice framework for nano-object identification, and identify research needs as a path forward. Discussion: Harmonized methods for identifying nanomaterials by size and count for many real-world samples do not currently exist. Although particle size remains the sole discriminating factor for classifying a material as “nano,” inconsistencies in size metrology will continue to confound policy and decision making. Moreover, there are concerns that the casting of a wide net with still-unproven metrology methods may stifle the development and judicious implementation of sustainable nanotechnologies. Based on the current state of the art, we propose a tiered approach for evaluating materials. To enable future risk-based refinements of these emerging definitions, we recommend that this framework also be considered in environmental and human health research involving the implications of nanomaterials. Conclusion: Substantial scientific scrutiny is needed in the area of nanomaterial metrology to establish best practices and to develop suitable methods before implementing definitions based solely on number percent nano-object content for regulatory purposes. Strong cooperation between industry, academia, and research institutions will be required to fully develop and implement detailed frameworks for nanomaterial identification with respect to emerging count-based metrics. Citation: Brown SC, Boyko V, Meyers G, Voetz M, Wohlleben W. 2013. Toward advancing nano-object count metrology: a best practice framework. Environ Health Perspect 121:1282–1291; http://dx.doi

Development of 1.45-mm resolution four-layer DOI-PET detector for simultaneous measurement in 3T MRI.

PubMed

Nishikido, Fumihiko; Tachibana, Atsushi; Obata, Takayuki; Inadama, Naoko; Yoshida, Eiji; Suga, Mikio; Murayama, Hideo; Yamaya, Taiga

2015-01-01

Recently, various types of PET-MRI systems have been developed by a number of research groups. However, almost all of the PET detectors used in these PET-MRI systems have no depth-of-interaction (DOI) capability. The DOI detector can reduce the parallax error and lead to improvement of the performance. We are developing a new PET-MRI system which consists of four-layer DOI detectors positioned close to the measured object to achieve high spatial resolution and high scanner sensitivity. As a first step, we are investigating influences the PET detector and the MRI system have on each other using a prototype four-layer DOI-PET detector. This prototype detector consists of a lutetium yttrium orthosilicate crystal block and a 4 × 4 multi-pixel photon counter array. The size of each crystal element is 1.45 mm × 1.45 mm × 4.5 mm, and the crystals are arranged in 6 × 6 elements × 4 layers with reflectors. The detector and some electric components are packaged in an aluminum shielding box. Experiments were carried out with 3.0 T MRI (GE, Signa HDx) and a birdcage-type RF coil. We demonstrated that the DOI-PET detector was normally operated in simultaneous measurements with no influence of the MRI measurement. A slight influence of the PET detector on the static magnetic field of the MRI was observed near the PET detector. The signal-to-noise ratio was decreased by presence of the PET detector due to environmental noise entering the MRI room through the cables, even though the PET detector was not powered up. On the other hand, no influence of electric noise from the PET detector in the simultaneous measurement on the MRI images was observed, even though the PET detector was positioned near the RF coil.

A multiplexed TOF and DOI capable PET detector using a binary position sensitive network.

PubMed

Bieniosek, M F; Cates, J W; Levin, C S

2016-11-07

Time of flight (TOF) and depth of interaction (DOI) capabilities can significantly enhance the quality and uniformity of positron emission tomography (PET) images. Many proposed TOF/DOI PET detectors require complex readout systems using additional photosensors, active cooling, or waveform sampling. This work describes a high performance, low complexity, room temperature TOF/DOI PET module. The module uses multiplexed timing channels to significantly reduce the electronic readout complexity of the PET detector while maintaining excellent timing, energy, and position resolution. DOI was determined using a two layer light sharing scintillation crystal array with a novel binary position sensitive network. A 20 mm effective thickness LYSO crystal array with four 3 mm  ×  3 mm silicon photomultipliers (SiPM) read out by a single timing channel, one energy channel and two position channels achieved a full width half maximum (FWHM) coincidence time resolution of 180  ±  2 ps with 10 mm of DOI resolution and 11% energy resolution. With sixteen 3 mm  ×  3 mm SiPMs read out by a single timing channel, one energy channel and four position channels a coincidence time resolution 204  ±  1 ps was achieved with 10 mm of DOI resolution and 15% energy resolution. The methods presented here could significantly simplify the construction of high performance TOF/DOI PET detectors.

Eliminating Unwanted Far-Field Excitation in Objective-Type TIRF. Part I. Identifying Sources of Nonevanescent Excitation Light

PubMed Central

Brunstein, Maia; Teremetz, Maxime; Hérault, Karine; Tourain, Christophe; Oheim, Martin

2014-01-01

Total internal reflection fluorescence microscopy (TIRFM) achieves subdiffraction axial sectioning by confining fluorophore excitation to a thin layer close to the cell/substrate boundary. However, it is often unknown how thin this light sheet actually is. Particularly in objective-type TIRFM, large deviations from the exponential intensity decay expected for pure evanescence have been reported. Nonevanescent excitation light diminishes the optical sectioning effect, reduces contrast, and renders TIRFM-image quantification uncertain. To identify the sources of this unwanted fluorescence excitation in deeper sample layers, we here combine azimuthal and polar beam scanning (spinning TIRF), atomic force microscopy, and wavefront analysis of beams passing through the objective periphery. Using a variety of intracellular fluorescent labels as well as negative staining experiments to measure cell-induced scattering, we find that azimuthal beam spinning produces TIRFM images that more accurately portray the real fluorophore distribution, but these images are still hampered by far-field excitation. Furthermore, although clearly measureable, cell-induced scattering is not the dominant source of far-field excitation light in objective-type TIRF, at least for most types of weakly scattering cells. It is the microscope illumination optical path that produces a large cell- and beam-angle invariant stray excitation that is insensitive to beam scanning. This instrument-induced glare is produced far from the sample plane, inside the microscope illumination optical path. We identify stray reflections and high-numerical aperture aberrations of the TIRF objective as one important source. This work is accompanied by a companion paper (Pt.2/2). PMID:24606927

Trustworthy persistent identifier systems of the future

NASA Astrophysics Data System (ADS)

Golodoniuc, Pavel; Klump, Jens; Car, Nicholas

2016-04-01

Over the last two decades, persistent identifier (PID) systems have seen some significant changes in their governance policies, system capabilities, and technology. The development of most systems was driven by two main application areas, namely archives and libraries. Guidelines and criteria for trustworthy PID systems have been clearly devised (Bütikofer, 2009) and many PID system implementations for the identification of static digital objects have been built (e.g., PURL). However systems delivering persistent identifiers for dynamic datasets are not yet mature. There has been a rapid proliferation of different PID systems caused by the specific technical or organisational requirements of various communities that could not be met by existing systems such as DOI, ISBN, and EAN. Many of these different systems were limited by their inability to provide native means of persistent identifier resolution. This has prompted a decoupling of PID-associated data from the resolution service and this is where the Handle system has played a significant role. The Handle allowed to build a distributed system of independently managed resolver services. A trustworthy PID system must be designed to outlive the objects it provides persistent identifiers for, which may cease to exist or otherwise be deprecated, and the technology used to implement it, which will certainly need to change with time. We propose that such a system should rest on four pillars of agreements - (i) definitions, (ii) policies, (iii) services, and (iv) data services, to ensure longevity. While we believe all four pillars are equally important, we intentionally leave regulating aspects of issuing of identifiers and their registration out of the scope of this paper and focus on the agreements that have to be established between PID resolver services and the data sources indicated by the persistent identifiers. We propose an approach to development of PID systems that combines the use of (a) the Handle system

A High Resolution Monolithic Crystal, DOI, MR Compatible, PET Detector

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robert S Miyaoka

The principle objective of this proposal is to develop a positron emission tomography (PET) detector with depth-of-interaction (DOI) positioning capability that will achieve state of the art spatial resolution and sensitivity performance for small animal PET imaging. When arranged in a ring or box detector geometry, the proposed detector module will support <1 mm3 image resolution and >15% absolute detection efficiency. The detector will also be compatible with operation in a MR scanner to support simultaneous multi-modality imaging. The detector design will utilize a thick, monolithic crystal scintillator readout by a two-dimensional array of silicon photomultiplier (SiPM) devices using amore » novel sensor on the entrance surface (SES) design. Our hypothesis is that our single-ended readout SES design will provide an effective DOI positioning performance equivalent to more expensive dual-ended readout techniques and at a significantly lower cost. Our monolithic crystal design will also lead to a significantly lower cost system. It is our goal to design a detector with state of the art performance but at a price point that is affordable so the technology can be disseminated to many laboratories. A second hypothesis is that using SiPM arrays, the detector will be able to operate in a MR scanner without any degradation in performance to support simultaneous PET/MR imaging. Having a co-registered MR image will assist in radiotracer localization and may also be used for partial volume corrections to improve radiotracer uptake quantitation. The far reaching goal of this research is to develop technology for medical research that will lead to improvements in human health care.« less

43 CFR 2.34 - Where can I get a copy of DOI's FOIA annual report?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Where can I get a copy of DOI's FOIA... AND TESTIMONY; FREEDOM OF INFORMATION ACT FOIA Annual Report § 2.34 Where can I get a copy of DOI's FOIA annual report? Under 5 U.S.C. 552(e), DOI is required to prepare an annual report regarding its...

Optimization, evaluation and calibration of a cross-strip DOI detector

NASA Astrophysics Data System (ADS)

Schmidt, F. P.; Kolb, A.; Pichler, B. J.

2018-02-01

This study depicts the evaluation of a SiPM detector with depth of interaction (DOI) capability via a dual-sided readout that is suitable for high-resolution positron emission tomography and magnetic resonance (PET/MR) imaging. Two different 12  ×  12 pixelated LSO scintillator arrays with a crystal pitch of 1.60 mm are examined. One array is 20 mm-long with a crystal separation by the specular reflector Vikuiti enhanced specular reflector (ESR), and the other one is 18 mm-long and separated by the diffuse reflector Lumirror E60 (E60). An improvement in energy resolution from 22.6% to 15.5% for the scintillator array with the E60 reflector is achieved by taking a nonlinear light collection correction into account. The results are FWHM energy resolutions of 14.0% and 15.5%, average FWHM DOI resolutions of 2.96 mm and 1.83 mm, and FWHM coincidence resolving times of 1.09 ns and 1.48 ns for the scintillator array with the ESR and that with the E60 reflector, respectively. The measured DOI signal ratios need to be assigned to an interaction depth inside the scintillator crystal. A linear and a nonlinear method, using the intrinsic scintillator radiation from lutetium, are implemented for an easy to apply calibration and are compared to the conventional method, which exploits a setup with an externally collimated radiation beam. The deviation between the DOI functions of the linear or nonlinear method and the conventional method is determined. The resulting average of differences in DOI positions is 0.67 mm and 0.45 mm for the nonlinear calibration method for the scintillator array with the ESR and with the E60 reflector, respectively; Whereas the linear calibration method results in 0.51 mm and 0.32 mm for the scintillator array with the ESR and the E60 reflector, respectively; and is, due to its simplicity, also applicable in assembled detector systems.

Optimization, evaluation and calibration of a cross-strip DOI detector.

PubMed

Schmidt, F P; Kolb, A; Pichler, B J

2018-02-20

This study depicts the evaluation of a SiPM detector with depth of interaction (DOI) capability via a dual-sided readout that is suitable for high-resolution positron emission tomography and magnetic resonance (PET/MR) imaging. Two different 12  ×  12 pixelated LSO scintillator arrays with a crystal pitch of 1.60 mm are examined. One array is 20 mm-long with a crystal separation by the specular reflector Vikuiti enhanced specular reflector (ESR), and the other one is 18 mm-long and separated by the diffuse reflector Lumirror E60 (E60). An improvement in energy resolution from 22.6% to 15.5% for the scintillator array with the E60 reflector is achieved by taking a nonlinear light collection correction into account. The results are FWHM energy resolutions of 14.0% and 15.5%, average FWHM DOI resolutions of 2.96 mm and 1.83 mm, and FWHM coincidence resolving times of 1.09 ns and 1.48 ns for the scintillator array with the ESR and that with the E60 reflector, respectively. The measured DOI signal ratios need to be assigned to an interaction depth inside the scintillator crystal. A linear and a nonlinear method, using the intrinsic scintillator radiation from lutetium, are implemented for an easy to apply calibration and are compared to the conventional method, which exploits a setup with an externally collimated radiation beam. The deviation between the DOI functions of the linear or nonlinear method and the conventional method is determined. The resulting average of differences in DOI positions is 0.67 mm and 0.45 mm for the nonlinear calibration method for the scintillator array with the ESR and with the E60 reflector, respectively; Whereas the linear calibration method results in 0.51 mm and 0.32 mm for the scintillator array with the ESR and the E60 reflector, respectively; and is, due to its simplicity, also applicable in assembled detector systems.

30 CFR 250.1006 - How must I decommission and take out of service a DOI pipeline?

Code of Federal Regulations, 2011 CFR

2011-07-01

... a DOI pipeline? 250.1006 Section 250.1006 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT... out of service a DOI pipeline? (a) The requirements for decommissioning pipelines are listed in § 250.1750 through § 250.1754. (b) The table in this section lists the requirements if you take a DOI...

30 CFR 250.1006 - How must I decommission and take out of service a DOI pipeline?

Code of Federal Regulations, 2010 CFR

2010-07-01

... a DOI pipeline? 250.1006 Section 250.1006 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT... and Pipeline Rights-of-Way § 250.1006 How must I decommission and take out of service a DOI pipeline...) The table in this section lists the requirements if you take a DOI pipeline out of service: If you...

Persistent Identifiers: a Prerequisite to Establish the Framework for Scholarly Link Exchange—Scholix

NASA Astrophysics Data System (ADS)

Stocker, M.; Mokrane, M.; Burton, A.; Koers, H.

2016-12-01

The Scholix framework—Scholarly Link Exchange—is a set of aspirational principles and practical guidelines developed under the umbrella of a joint Working Group of the Research Data Alliance (RDA) and the World Data System (WDS). It supports a global open information ecosystem unveiling the links between scholarly literature and underpinning research data. The core objectives of the framework are to (1) increase visibility and discoverability of data and articles, (2) place data in context to enable re-use, and (3) support credit attribution mechanisms. Thus, facilitating reproducibility and the transparent evaluation of science. Scholix provides an evolving lightweight set of Guidelines to increase interoperability rather than a normative standard. It consists initially of a conceptual and information models, information standards and encoding guidelines, and options for encoding and exchange protocols. An essential prerequisite to enable the proposed framework is the use of global, unique and persistent identifiers for research objects (such as data and literature). Scholix provides incentives and encourages best practice in the use of such identifiers and standardised referencing. The Data and Literature Interlinking Service (DLI: dliservice.research-infrastructures.eu) is the first exemplar of an aggregation and query service supported by the Scholix framework which will allow the emergence of third party services such as domain-specific aggregations, integrations with other global services, discovery tools, impact assessments, etc. Scholix is already implemented by existing hubs or global aggregators of data-literature link information such as DataCite, CrossRef, OpenAIRE, and EMBL-EBI building on the capacities of existing Persistent Identifier Systems (PIDs) such as Digital Object Identifiers (DOI) and Accession Numbers. These hubs in turn work with their natural communities of data centres or literature publishers to collect the information through

77 FR 17493 - Agency Information Collection Activities: Proposed Collection; Comment Request; DOI Generic...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-26

... Don Bieniewicz at DOI via email at [email protected]ios.doi.gov or via facsimile (202) 208-4867. FOR... yield quantitative results that can be generalized to the population of study. This feedback will... operations might improve delivery of products or services. These collections will allow for ongoing...

2 CFR 1401.500 - What are my responsibilities as a DOI awarding official?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false What are my responsibilities as a DOI awarding official? 1401.500 Section 1401.500 Grants and Agreements Federal Agency Regulations for Grants... responsibilities as a DOI awarding official? To obtain a recipient's agreement to comply with applicable...

Technique for identifying, tracing, or tracking objects in image data

DOEpatents

Anderson, Robert J [Albuquerque, NM; Rothganger, Fredrick [Albuquerque, NM

2012-08-28

A technique for computer vision uses a polygon contour to trace an object. The technique includes rendering a polygon contour superimposed over a first frame of image data. The polygon contour is iteratively refined to more accurately trace the object within the first frame after each iteration. The refinement includes computing image energies along lengths of contour lines of the polygon contour and adjusting positions of the contour lines based at least in part on the image energies.

43 CFR 2.34 - Where can I get a copy of DOI's FOIA annual report?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Where can I get a copy of DOI's FOIA annual report? 2.34 Section 2.34 Public Lands: Interior Office of the Secretary of the Interior RECORDS AND TESTIMONY; FREEDOM OF INFORMATION ACT FOIA Annual Report § 2.34 Where can I get a copy of DOI's FOIA annual report? Under 5 U.S.C. 552(e), DOI is...

Use of Persistent Identifiers to link Heterogeneous Data Systems in the Integrated Earth Data Applications (IEDA) Facility

NASA Astrophysics Data System (ADS)

Hsu, L.; Lehnert, K. A.; Carbotte, S. M.; Arko, R. A.; Ferrini, V.; O'hara, S. H.; Walker, J. D.

2012-12-01

The Integrated Earth Data Applications (IEDA) facility maintains multiple data systems with a wide range of solid earth data types from the marine, terrestrial, and polar environments. Examples of the different data types include syntheses of ultra-high resolution seafloor bathymetry collected on large collaborative cruises and analytical geochemistry measurements collected by single investigators in small, unique projects. These different data types have historically been channeled into separate, discipline-specific databases with search and retrieval tailored for the specific data type. However, a current major goal is to integrate data from different systems to allow interdisciplinary data discovery and scientific analysis. To increase discovery and access across these heterogeneous systems, IEDA employs several unique IDs, including sample IDs (International Geo Sample Number, IGSN), person IDs (GeoPass ID), funding award IDs (NSF Award Number), cruise IDs (from the Marine Geoscience Data System Expedition Metadata Catalog), dataset IDs (DOIs), and publication IDs (DOIs). These IDs allow linking of a sample registry (System for Earth SAmple Registration), data libraries and repositories (e.g. Geochemical Research Library, Marine Geoscience Data System), integrated synthesis databases (e.g. EarthChem Portal, PetDB), and investigator services (IEDA Data Compliance Tool). The linked systems allow efficient discovery of related data across different levels of granularity. In addition, IEDA data systems maintain links with several external data systems, including digital journal publishers. Links have been established between the EarthChem Portal and ScienceDirect through publication DOIs, returning sample-level objects and geochemical analyses for a particular publication. Linking IEDA-hosted data to digital publications with IGSNs at the sample level and with IEDA-allocated dataset DOIs are under development. As an example, an individual investigator could sign up

Implementation of Data Citations and Persistent Identifiers at the ORNL DAAC

NASA Astrophysics Data System (ADS)

Cook, R. B.; Santhana Vannan, S.; Devarakonda, Ranjeet; McMurry, B. F.; Kidder, J. H.; Shanafield, H. A.; Palanisamy, G.

2013-12-01

As research in Earth Science becomes more data intensive, a critical requirement of data archives is that data needs to be easily discovered, accessed, and used. One approach to improving data discovery and access is through data citations coupled with Digital Object Identifiers (DOI). Beginning in 1998, the Oak Ridge National Laboratory Distributed Active Archive Center (ORNL DAAC) has issued data product citations that have been accepted and used in AGU and other peer-reviewed journals. Citation elements established by the ORNL DAAC are similar to those used for journal articles (authors, titles, information to locate, and version), and beginning in 2007 included a DOI that is persistent, actionable, specific, and complete. The citation approach used at the DAAC also allows for referring to specific subsets of the data, by including within the citation the temporal and spatial portions of the data actually used. Citations allow others to find data and reproduce the results of the research article, and also use those data to test new hypotheses, design new sample collections, or construct or evaluate models. In addition to enhancing discovery and access of the data used in a research article, the citation gives credit to data generators, data centers and their funders, and, through citation indices, determine the scientific impact of a data set. The ORNL DAAC has developed a database that links research articles and their use of ORNL DAAC data products. The database allows determination of who, in which journal, and how the data have been used, in a manner analogous to author citation indices. The ORNL DAAC has been an initial contributor to the Thomson Reuters Data Citation Index. In addition, research data products deposited at the ORNL DAAC are linked using DOIs to relevant articles in Elsevier journals available on ScienceDirect. The ultimate goal of this implementation is that citations to data products become a routine part of the scientific process.

25 CFR 1000.232 - When must DOI respond to a request for reconsideration?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false When must DOI respond to a request for reconsideration? 1000.232 Section 1000.232 Indians OFFICE OF THE ASSISTANT SECRETARY, INDIAN AFFAIRS, DEPARTMENT OF THE...-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.232 When must DOI respond to a request for...

DOI Use of AVIRIS Data in Natural Resources Management: A Technology Transfer Project Status Report

NASA Technical Reports Server (NTRS)

Getter, James R.; Wickland, Diane

1998-01-01

A meeting was held in December 1996, attended by representatives from Department of the Interior (DOI) and National Aeronautical and Space Administration (NASA) at the request of Department of the Interior Secretary, Bruce Babbitt and NASA, Administrator Director Dan Goldin, to discuss the use of hyperspectral systems and related remote sensing technologies in addressing environmental issues of environmental importance to the (DOI). It was determined that NASA/DOI Coordination be established, comprised of representatives from each agency, designated to address the environmental issues and resulting technologies. A steering committee was formed consisting of representatives from NASA Headquarters, NASA PI's from University California-Davis, University of Colorado-Boulder, University of New Hampshire and DOI Bureaus (Indian Affairs, Land Management, Reclamation, National Park Service, and US Geological Survey).

Student generated learning objectives: extent of congruence with faculty set objectives and factors influencing their generation.

PubMed

Abdul Ghaffar Al-Shaibani, Tarik A; Sachs-Robertson, Annette; Al Shazali, Hafiz O; Sequeira, Reginald P; Hamdy, Hosam; Al-Roomi, Khaldoon

2003-07-01

A problem-based learning strategy is used for curriculum planning and implementation at the Arabian Gulf University, Bahrain. Problems are constructed in a way that faculty-set objectives are expected to be identified by students during tutorials. Students in small groups, along with a tutor functioning as a facilitator, identify learning issues and define their learning objectives. We compared objectives identified by student groups with faculty-set objectives to determine extent of congruence, and identified factors that influenced students' ability at identifying faculty-set objectives. Male and female students were segregated and randomly grouped. A faculty tutor was allocated for each group. This study was based on 13 problems given to entry-level medical students. Pooled objectives of these problems were classified into four categories: structural, functional, clinical and psychosocial. Univariate analysis of variance was used for comparison, and a p > 0.05 was considered significant. The mean of overall objectives generated by the students was 54.2%, for each problem. Students identified psychosocial learning objectives more readily than structural ones. Female students identified more psychosocial objectives, whereas male students identified more of structural objectives. Tutor characteristics such as medical/non-medical background, and the years of teaching were correlated with categories of learning issues identified. Students identify part of the faculty-set learning objectives during tutorials with a faculty tutor acting as a facilitator. Students' gender influences types of learning issues identified. Content expertise of tutors does not influence identification of learning needs by students.

41 CFR 102-75.665 - What happens after the disposal agency receives the assignment recommendation from DOI?

Code of Federal Regulations, 2011 CFR

2011-01-01

... disposal agency receives the assignment recommendation from DOI? 102-75.665 Section 102-75.665 Public... assignment recommendation from DOI? If, after considering other uses for the property, the disposal agency approves the assignment recommendation from DOI, it must assign the property by letter or other document to...

Identifying Anomalous Citations for Objective Evaluation of Scholarly Article Impact.

PubMed

Bai, Xiaomei; Xia, Feng; Lee, Ivan; Zhang, Jun; Ning, Zhaolong

2016-01-01

Evaluating the impact of a scholarly article is of great significance and has attracted great attentions. Although citation-based evaluation approaches have been widely used, these approaches face limitations e.g. in identifying anomalous citations patterns. This negligence would inevitably cause unfairness and inaccuracy to the article impact evaluation. In this study, in order to discover the anomalous citations and ensure the fairness and accuracy of research outcome evaluation, we investigate the citation relationships between articles using the following factors: collaboration times, the time span of collaboration, citing times and the time span of citing to weaken the relationship of Conflict of Interest (COI) in the citation network. Meanwhile, we study a special kind of COI, namely suspected COI relationship. Based on the COI relationship, we further bring forward the COIRank algorithm, an innovative scheme for accurately assessing the impact of an article. Our method distinguishes the citation strength, and utilizes PageRank and HITS algorithms to rank scholarly articles comprehensively. The experiments are conducted on the American Physical Society (APS) dataset. We find that about 80.88% articles contain contributed citations by co-authors in 26,366 articles and 75.55% articles among these articles are cited by the authors belonging to the same affiliation, indicating COI and suspected COI should not be ignored for evaluating impact of scientific papers objectively. Moreover, our experimental results demonstrate COIRank algorithm significantly outperforms the state-of-art solutions. The validity of our approach is verified by using the probability of Recommendation Intensity.

Brain regions involved in subprocesses of small-space episodic object-location memory: a systematic review of lesion and functional neuroimaging studies.

PubMed

Zimmermann, Kathrin; Eschen, Anne

2017-04-01

Object-location memory (OLM) enables us to keep track of the locations of objects in our environment. The neurocognitive model of OLM (Postma, A., Kessels, R. P. C., & Van Asselen, M. (2004). The neuropsychology of object-location memory. In G. L. Allen (Ed.), Human spatial memory: Remembering where (pp. 143-160). Mahwah, NJ: Lawrence Erlbaum, Postma, A., Kessels, R. P. C., & Van Asselen, M. (2008). How the brain remembers and forgets where things are: The neurocognition of object-location memory. Neuroscience & Biobehavioral Reviews, 32, 1339-1345. doi: 10.1016/j.neubiorev.2008.05.001 ) proposes that distinct brain regions are specialised for different subprocesses of OLM (object processing, location processing, and object-location binding; categorical and coordinate OLM; egocentric and allocentric OLM). It was based mainly on findings from lesion studies. However, recent episodic memory studies point to a contribution of additional or different brain regions to object and location processing within episodic OLM. To evaluate and update the neurocognitive model of OLM, we therefore conducted a systematic literature search for lesion as well as functional neuroimaging studies contrasting small-space episodic OLM with object memory or location memory. We identified 10 relevant lesion studies and 8 relevant functional neuroimaging studies. We could confirm some of the proposals of the neurocognitive model of OLM, but also differing hypotheses from episodic memory research, about which brain regions are involved in the different subprocesses of small-space episodic OLM. In addition, we were able to identify new brain regions as well as important research gaps.

41 CFR 102-75.670 - What responsibilities does DOI have after receiving the disposal agency's assignment letter?

Code of Federal Regulations, 2010 CFR

2010-07-01

... does DOI have after receiving the disposal agency's assignment letter? 102-75.670 Section 102-75.670... Property for Use As Public Park Or Recreation Areas § 102-75.670 What responsibilities does DOI have after..., the Secretary may proceed with the transfer. DOI must take all necessary actions to accomplish the...

41 CFR 102-75.670 - What responsibilities does DOI have after receiving the disposal agency's assignment letter?

Code of Federal Regulations, 2011 CFR

2011-01-01

... does DOI have after receiving the disposal agency's assignment letter? 102-75.670 Section 102-75.670... Property for Use As Public Park Or Recreation Areas § 102-75.670 What responsibilities does DOI have after..., the Secretary may proceed with the transfer. DOI must take all necessary actions to accomplish the...

A novel method to calibrate DOI function of a PET detector with a dual-ended-scintillator readout.

PubMed

Shao, Yiping; Yao, Rutao; Ma, Tianyu

2008-12-01

The detection of depth-of-interaction (DOI) is a critical detector capability to improve the PET spatial resolution uniformity across the field-of-view and will significantly enhance, in particular, small bore system performance for brain, breast, and small animal imaging. One promising technique of DOI detection is to use dual-ended-scintillator readout that uses two photon sensors to detect scintillation light from both ends of a scintillator array and estimate DOI based on the ratio of signals (similar to Anger logic). This approach needs a careful DOI function calibration to establish accurate relationship between DOI and signal ratios, and to recalibrate if the detection condition is shifted due to the drift of sensor gain, bias variations, or degraded optical coupling, etc. However, the current calibration method that uses coincident events to locate interaction positions inside a single scintillator crystal has severe drawbacks, such as complicated setup, long and repetitive measurements, and being prone to errors from various possible misalignments among the source and detector components. This method is also not practically suitable to calibrate multiple DOI functions of a crystal array. To solve these problems, a new method has been developed that requires only a uniform flood source to irradiate a crystal array without the need to locate the interaction positions, and calculates DOI functions based solely on the uniform probability distribution of interactions over DOI positions without knowledge or assumption of detector responses. Simulation and experiment have been studied to validate the new method, and the results show that the new method, with a simple setup and one single measurement, can provide consistent and accurate DOI functions for the entire array of multiple scintillator crystals. This will enable an accurate, simple, and practical DOI function calibration for the PET detectors based on the design of dual-ended-scintillator readout. In

A novel method to calibrate DOI function of a PET detector with a dual-ended-scintillator readout

DOE Office of Scientific and Technical Information (OSTI.GOV)

Shao Yiping; Yao Rutao; Ma Tianyu

The detection of depth-of-interaction (DOI) is a critical detector capability to improve the PET spatial resolution uniformity across the field-of-view and will significantly enhance, in particular, small bore system performance for brain, breast, and small animal imaging. One promising technique of DOI detection is to use dual-ended-scintillator readout that uses two photon sensors to detect scintillation light from both ends of a scintillator array and estimate DOI based on the ratio of signals (similar to Anger logic). This approach needs a careful DOI function calibration to establish accurate relationship between DOI and signal ratios, and to recalibrate if the detectionmore » condition is shifted due to the drift of sensor gain, bias variations, or degraded optical coupling, etc. However, the current calibration method that uses coincident events to locate interaction positions inside a single scintillator crystal has severe drawbacks, such as complicated setup, long and repetitive measurements, and being prone to errors from various possible misalignments among the source and detector components. This method is also not practically suitable to calibrate multiple DOI functions of a crystal array. To solve these problems, a new method has been developed that requires only a uniform flood source to irradiate a crystal array without the need to locate the interaction positions, and calculates DOI functions based solely on the uniform probability distribution of interactions over DOI positions without knowledge or assumption of detector responses. Simulation and experiment have been studied to validate the new method, and the results show that the new method, with a simple setup and one single measurement, can provide consistent and accurate DOI functions for the entire array of multiple scintillator crystals. This will enable an accurate, simple, and practical DOI function calibration for the PET detectors based on the design of dual-ended-scintillator readout

Sensitivity booster for DOI-PET scanner by utilizing Compton scattering events between detector blocks

NASA Astrophysics Data System (ADS)

Yoshida, Eiji; Tashima, Hideaki; Yamaya, Taiga

2014-11-01

In a conventional PET scanner, coincidence events are measured with a limited energy window for detection of photoelectric events in order to reject Compton scatter events that occur in a patient, but Compton scatter events caused in detector crystals are also rejected. Scatter events within the patient causes scatter coincidences, but inter crystal scattering (ICS) events have useful information for determining an activity distribution. Some researchers have reported the feasibility of PET scanners based on a Compton camera for tracing ICS into the detector. However, these scanners require expensive semiconductor detectors for high-energy resolution. In the Anger-type block detector, single photons interacting with multiple detectors can be obtained for each interacting position and complete information can be gotten just as for photoelectric events in the single detector. ICS events in the single detector have been used to get coincidence, but single photons interacting with multiple detectors have not been used to get coincidence. In this work, we evaluated effect of sensitivity improvement using Compton kinetics in several types of DOI-PET scanners. The proposed method promises to improve the sensitivity using coincidence events of single photons interacting with multiple detectors, which are identified as the first interaction (FI). FI estimation accuracy can be improved to determine FI validity from the correlation between Compton scatter angles calculated on the coincidence line-of-response. We simulated an animal PET scanner consisting of 42 detectors. Each detector block consists of three types of scintillator crystals (LSO, GSO and GAGG). After the simulation, coincidence events are added as information for several depth-of-interaction (DOI) resolutions. From the simulation results, we concluded the proposed method promises to improve the sensitivity considerably when effective atomic number of a scintillator is low. Also, we showed that FI estimate

The Near-Earth Object Human Space Flight Accessible Targets Study (NHATS) List of Near-Earth Asteroids: Identifying Potential Targets for Future Exploration

NASA Technical Reports Server (NTRS)

Abell, Paul A.; Barbee, B. W.; Mink, R. G.; Alberding, C. M.; Adamo, D. R.; Mazanek, D. D.; Johnson, L. N.; Yeomans, D. K.; Chodas, P. W.; Chamberlin, A. B.;

Implementation of data citations and persistent identifiers at the ORNL DAAC

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cook, Robert B.; Vannan, Suresh K. S.; McMurry, Benjamin F.

A requirement of data archives is that data holdings can be easily discovered, accessed, and used. One approach to improving data discovery and access is through data citations coupled with Digital Object Identifiers (DOI). The Oak Ridge National Laboratory Distributed Active Archive Center (ORNL DAAC) since 1998 has issued data citations that have been accepted and used in peer-reviewed journals. Citation elements established by the ORNL DAAC are similar to those used for journal articles (authors, year, product title, and information to locate), and beginning in 2007 included a DOI that is persistent, actionable, specific, and complete. The approach usedmore » at the ORNL DAAC also allows for referring to subsets of the data, by including within the citation the temporal and spatial extent, and parameters used. Data citations allow readers to find data and reproduce the results of the research article, and also use those data to test new hypotheses, design new sample collections, or construct or evaluate models. The ORNL DAAC uses a manual method to compile data citations and has developed a database that links research articles and their use of specific ORNL DAAC data products. Automation of the data citation compilation process, as is the case for articles, will enable data citations to become a more common practice. In addition to enhancing discovery and access of the data used in a research article, the citation gives credit to data generators, data centers and their funders, and, through citation indices, determine the scientific impact of a data set.« less

Implementation of data citations and persistent identifiers at the ORNL DAAC

DOE PAGES

Cook, Robert B.; Vannan, Suresh K. S.; McMurry, Benjamin F.; ...

2016-03-08

A requirement of data archives is that data holdings can be easily discovered, accessed, and used. One approach to improving data discovery and access is through data citations coupled with Digital Object Identifiers (DOI). The Oak Ridge National Laboratory Distributed Active Archive Center (ORNL DAAC) since 1998 has issued data citations that have been accepted and used in peer-reviewed journals. Citation elements established by the ORNL DAAC are similar to those used for journal articles (authors, year, product title, and information to locate), and beginning in 2007 included a DOI that is persistent, actionable, specific, and complete. The approach usedmore » at the ORNL DAAC also allows for referring to subsets of the data, by including within the citation the temporal and spatial extent, and parameters used. Data citations allow readers to find data and reproduce the results of the research article, and also use those data to test new hypotheses, design new sample collections, or construct or evaluate models. The ORNL DAAC uses a manual method to compile data citations and has developed a database that links research articles and their use of specific ORNL DAAC data products. Automation of the data citation compilation process, as is the case for articles, will enable data citations to become a more common practice. In addition to enhancing discovery and access of the data used in a research article, the citation gives credit to data generators, data centers and their funders, and, through citation indices, determine the scientific impact of a data set.« less

Erratum: Developmental Changes in Mental Rotation: A Dissociation Between Object-Based and Egocentric Transformations

PubMed Central

Kaltner, Sandra; Jansen, Petra

2017-01-01

This erratum reports an error in “Developmental changes in mental rotation: A dissociation between object-based and egocentric transformations” by Sandra Kaltner & Petra Jansen (Advances in Cognitive Psychology, 12, 67-78. doi: 10.5709/acp-0187-y). The error addresses the fact, that regarding developmental changes in object-based and egocentric transformations, there is only a difference found in children. The incorrect version found changes only in the adult group, but not within children or older adults. PMID:29201259

DOIs for Data: Progress in Data Citation and Publication in the Geosciences

NASA Astrophysics Data System (ADS)

Callaghan, S.; Murphy, F.; Tedds, J.; Allan, R.

2012-12-01

Identifiers for data are the bedrock on which data citation and publication rests. These, in their turn, are widely proposed as methods for encouraging researchers to share their datasets, and at the same time receive academic credit for their efforts in producing them. However, neither data citation nor publication can be properly achieved without a method of identifying clearly what is, and what isn't, part of the dataset. Once a dataset becomes part of the scientific record (either through formal data publication or through being cited) then issues such as dataset stability and permanence become vital to address. In the geosciences, several projects in the UK are concentrating on issues of dataset identification, citation and publication. The UK's Natural Environment Research Council's (NERC) Science Information Strategy data citation and publication project is addressing the issue of identifiers for data, stability, transparency, and credit for data producers through data citation. At a data publication level, 2012 has seen the launch of the new Wiley title Geoscience Data Journal and the PREPARDE (Peer Review for Publication & Accreditation of Research Data in the Earth sciences) project, both aiming to encourage data publication by addressing issues such as data paper submission workflows and the scientific peer-review of data. All of these initiatives work with a range of partners including academic institutions, learned societies, data centers and commercial publishers, both nationally and internationally, with a cross-project aim of developing the mechanisms so data can be identified, cited and published with confidence. This involves investigating barriers and drivers to data publishing and sharing, peer review, and re-use of geoscientific datasets, and specifically such topics as dataset requirements for citation, workflows for dataset ingestion into data centers and publishers, procedures and policies for editors, reviewers and authors of data

Scott and Doi conduct tool evaluations during second EVA of STS-87

NASA Image and Video Library

1997-12-03

STS087-341-004 (3 Dec. 1997) --- Backdropped over Africa, Takao Doi, international mission specialist representing Japan’s National Space Development Agency (NASDA), works with a crane device during a second extravehicular activity (EVA) designed to help evaluate techniques and hardware to be used in constructing the International Space Station (ISS). Takao Doi and astronaut Winston E. Scott (out of frame) were involved in the mission's second EVA in the cargo bay of the Earth-orbiting Space Shuttle Columbia. Takao Doi is working with a 156-pound crane designed to aid spacewalkers in transporting Orbital Replacement Units (ORU) from translation carts on the exterior of the ISS to various worksites on the truss structure. The view of Earth below features an inland delta in Mali (frame center). This view is from the east toward the west and was taken with a 35mm camera.

A Pan-Carina Young Stellar Object Catalog: Intermediate-mass Young Stellar Objects in the Carina Nebula Identified Via Mid-infrared Excess Emission

NASA Astrophysics Data System (ADS)

Povich, Matthew S.; Smith, Nathan; Majewski, Steven R.; Getman, Konstantin V.; Townsley, Leisa K.; Babler, Brian L.; Broos, Patrick S.; Indebetouw, Rémy; Meade, Marilyn R.; Robitaille, Thomas P.; Stassun, Keivan G.; Whitney, Barbara A.; Yonekura, Yoshinori; Fukui, Yasuo

2011-05-01

We present a catalog of 1439 young stellar objects (YSOs) spanning the 1.42 deg2 field surveyed by the Chandra Carina Complex Project (CCCP), which includes the major ionizing clusters and the most active sites of ongoing star formation within the Great Nebula in Carina. Candidate YSOs were identified via infrared (IR) excess emission from dusty circumstellar disks and envelopes, using data from the Spitzer Space Telescope (the Vela-Carina survey) and the Two-Micron All Sky Survey. We model the 1-24 μm IR spectral energy distributions of the YSOs to constrain physical properties. Our Pan-Carina YSO Catalog (PCYC) is dominated by intermediate-mass (2 M sun < m <~ 10 M sun) objects with disks, including Herbig Ae/Be stars and their less evolved progenitors. The PCYC provides a valuable complementary data set to the CCCP X-ray source catalogs, identifying 1029 YSOs in Carina with no X-ray detection. We also catalog 410 YSOs with X-ray counterparts, including 62 candidate protostars. Candidate protostars with X-ray detections tend to be more evolved than those without. In most cases, X-ray emission apparently originating from intermediate-mass, disk-dominated YSOs is consistent with the presence of low-mass companions, but we also find that X-ray emission correlates with cooler stellar photospheres and higher disk masses. We suggest that intermediate-mass YSOs produce X-rays during their early pre-main-sequence evolution, perhaps driven by magnetic dynamo activity during the convective atmosphere phase, but this emission dies off as the stars approach the main sequence. Extrapolating over the stellar initial mass function scaled to the PCYC population, we predict a total population of >2 × 104 YSOs and a present-day star formation rate (SFR) of >0.008 M sun yr-1. The global SFR in the Carina Nebula, averaged over the past ~5 Myr, has been approximately constant.

Color sensitive silicon photomultiplers with micro-cell level encoding for DOI PET detectors

NASA Astrophysics Data System (ADS)

Shimazoe, Kenji; Koyama, Akihiro; Takahashi, Hiroyuki; Ganka, Thomas; Iskra, Peter; Marquez Seco, Alicia; Schneider, Florian; Wiest, Florian

2017-11-01

There have been many studies on Depth Of Interaction (DOI) identification for high resolution Positron Emission Tomography (PET) systems, including those on phoswich detectors, double-sided readout, light sharing methods, and wavelength discrimination. The wavelength discrimination method utilizes the difference in wavelength of stacked scintillators and requires a color sensitive photodetector. Here, a new silicon photomultiplier (SiPM) coupled to a color filter (colorSiPM) was designed and fabricated for DOI detection. The fabricated colorSiPM has two anode readouts that are sensitive to blue and green color. The colorSiPM's response and DOI identification capability for stacked GAGG and LYSO crystals are characterized. The fabricated colorSiPM is sensitive enough to detect a peak of 662 keV from a 137 Cs source.

41 CFR 102-75.635 - What information must the Department of the Interior (DOI) furnish eligible public agencies?

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false What information must the Department of the Interior (DOI) furnish eligible public agencies? 102-75.635 Section 102-75.635... the Interior (DOI) furnish eligible public agencies? Upon request, DOI must furnish eligible public...

41 CFR 102-75.635 - What information must the Department of the Interior (DOI) furnish eligible public agencies?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false What information must the Department of the Interior (DOI) furnish eligible public agencies? 102-75.635 Section 102-75.635... the Interior (DOI) furnish eligible public agencies? Upon request, DOI must furnish eligible public...

43 CFR 2.5 - Does DOI maintain an index of its reading room materials?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Does DOI maintain an index of its reading room materials? 2.5 Section 2.5 Public Lands: Interior Office of the Secretary of the Interior RECORDS... a FOIA Request § 2.5 Does DOI maintain an index of its reading room materials? Each bureau will...

DOI Climate Science Centers--Regional science to address management priorities

USGS Publications Warehouse

O'Malley, Robin

2012-01-01

Our Nation's lands, waters, and ecosystems and the living and cultural resources they contain face myriad challenges from invasive species, the effects of changing land and water use, habitat fragmentation and degradation, and other influences. These challenges are compounded by increasing influences from a changing climate—higher temperatures, increasing droughts, floods, and wildfires, and overall increasing variability in weather and climate. The Department of the Interior (DOI) has established eight regional Climate Science Centers (CSC) (fig. 1) that will provide scientific information and tools to natural and cultural resource managers as they plan for conserving these resources in a changing world. The U.S. Geological Survey (USGS) National Climate Change and Wildlife Science Center (NCCWSC) is managing the CSCs on behalf of the DOI.

Pharmacological modulation of abnormal involuntary DOI-induced head twitch response in male DBA/2J mice: I. Effects of D2/D3 and D2 dopamine receptor selective compounds.

PubMed

Rangel-Barajas, Claudia; Malik, Maninder; Vangveravong, Suwanna; Mach, Robert H; Luedtke, Robert R

2014-08-01

Because of the complexity and heterogeneity of human neuropsychiatric disorders, it has been difficult to identify animal models that mimic the symptoms of these neuropathologies and can be used to screen for antipsychotic agents. For this study we selected the murine 5HT2A/2C receptor agonist-induced head twitch response (HTR) induced by the administration of 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), which has been proposed as an animal model of symptoms associated with a variety of behavioral and psychiatric conditions. We investigated the DOI-induced HTR in male DBA/2J mice using a panel of D2-like (D2, D3 and D4) and D2 dopamine receptor selective compounds. When DBA/2J mice were administered a daily dose of DOI (5 mg/kg), tolerance to the DOI occurs. However, administrations of the same dose of DOI every other day (48 h) or on a weekly basis did not lead to tolerance and the ability to induce tolerance after daily administration of DOI remains intact after repeated weekly administration of DOI. Subsequently, a panel of D2-like dopamine receptor antagonists was found to effectively inhibit the DOI-induced HTR in DBA/2J mice. However, the benzamide eticlopride, which is a high affinity D2-like antagonist, was a notable exception. SV 293, SV-III-130s and N-methylbenperidol, which exhibit a high affinity for D2 versus the D3 dopamine receptor subtypes (60- to 100-fold binding selectivity), were also found to inhibit the HTR in DBA/2J mice. This observation suggests a functional interaction between dopaminergic and serotonergic systems through D2 dopamine receptors and the 5-HT2A serotonin receptors in vivo. Copyright © 2014 Elsevier Ltd. All rights reserved.

Discovering Physical Samples Through Identifiers, Metadata, and Brokering

NASA Astrophysics Data System (ADS)

Arctur, D. K.; Hills, D. J.; Jenkyns, R.

2015-12-01

Physical samples, particularly in the geosciences, are key to understanding the Earth system, its history, and its evolution. Our record of the Earth as captured by physical samples is difficult to explain and mine for understanding, due to incomplete, disconnected, and evolving metadata content. This is further complicated by differing ways of classifying, cataloguing, publishing, and searching the metadata, especially when specimens do not fit neatly into a single domain—for example, fossils cross disciplinary boundaries (mineral and biological). Sometimes even the fundamental classification systems evolve, such as the geological time scale, triggering daunting processes to update existing specimen databases. Increasingly, we need to consider ways of leveraging permanent, unique identifiers, as well as advancements in metadata publishing that link digital records with physical samples in a robust, adaptive way. An NSF EarthCube Research Coordination Network (RCN) called the Internet of Samples (iSamples) is now working to bridge the metadata schemas for biological and geological domains. We are leveraging the International Geo Sample Number (IGSN) that provides a versatile system of registering physical samples, and working to harmonize this with the DataCite schema for Digital Object Identifiers (DOI). A brokering approach for linking disparate catalogues and classification systems could help scale discovery and access to the many large collections now being managed (sometimes millions of specimens per collection). This presentation is about our community building efforts, research directions, and insights to date.

Settlement with the Department of the Interior (DOI) to Resolve Violations at Schools in Indian Country

EPA Pesticide Factsheets

Consent Agreement with the DOI, BIA and Bureau of Indian Education (BIE) on alleged violations at schools and public water systems owned, operated or the responsibility of DOI. Violations occurred under the CAA, CWA, SDWA, TSCA, ADHERA.

43 CFR 2.2 - What is DOI's policy regarding release of records under the FOIA?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false What is DOI's policy regarding release of... RECORDS AND TESTIMONY; FREEDOM OF INFORMATION ACT General Information § 2.2 What is DOI's policy regarding... public consistent with the spirit of the FOIA and the Privacy Act. ...

43 CFR 2.5 - Does DOI maintain an index of its reading room materials?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false Does DOI maintain an index of its reading room materials? 2.5 Section 2.5 Public Lands: Interior Office of the Secretary of the Interior RECORDS AND TESTIMONY; FREEDOM OF INFORMATION ACT Information Routinely Available to the Public without Filing a FOIA Request § 2.5 Does DOI maintain an...

43 CFR 2.5 - Does DOI maintain an index of its reading room materials?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true Does DOI maintain an index of its reading room materials? 2.5 Section 2.5 Public Lands: Interior Office of the Secretary of the Interior RECORDS AND TESTIMONY; FREEDOM OF INFORMATION ACT Information Routinely Available to the Public without Filing a FOIA Request § 2.5 Does DOI maintain an...

43 CFR 2.32 - How long does DOI have to respond to my appeal?

Code of Federal Regulations, 2010 CFR

2010-10-01

... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false How long does DOI have to respond to my appeal? 2.32 Section 2.32 Public Lands: Interior Office of the Secretary of the Interior RECORDS AND TESTIMONY; FREEDOM OF INFORMATION ACT FOIA Appeals § 2.32 How long does DOI have to respond to my appeal? (a...

43 CFR 2.32 - How long does DOI have to respond to my appeal?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false How long does DOI have to respond to my appeal? 2.32 Section 2.32 Public Lands: Interior Office of the Secretary of the Interior RECORDS AND TESTIMONY; FREEDOM OF INFORMATION ACT FOIA Appeals § 2.32 How long does DOI have to respond to my appeal? (a...

76 FR 77244 - Renewal of Information Collection; OMB Control Number 1040-0001, DOI Programmatic Clearance for...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-12

... Number 1040-0001, DOI Programmatic Clearance for Customer Satisfaction Surveys AGENCY: Department of [email protected] . Reference ``DOI Programmatic Clearance for Customer Satisfaction Surveys'' in your email... public accountability by promoting a new focus on results, service quality, and customer satisfaction...

"Doi Moi" (Renovation) and Higher Education Reform in Vietnam

ERIC Educational Resources Information Center

Thanh, Pham Thi Hong

2011-01-01

Vietnam has experienced significant social, economic, political, and educational changes during the last two decades since the "Doi Moi" policy was implemented. To respond to new requirements required by the global economy, Vietnamese education has undergone remarkable reforms. This article critically examines these reforms in three…

Functional genome-wide siRNA screen identifies KIAA0586 as mutated in Joubert syndrome

PubMed Central

Roosing, Susanne; Hofree, Matan; Kim, Sehyun; Scott, Eric; Copeland, Brett; Romani, Marta; Silhavy, Jennifer L; Rosti, Rasim O; Schroth, Jana; Mazza, Tommaso; Miccinilli, Elide; Zaki, Maha S; Swoboda, Kathryn J; Milisa-Drautz, Joanne; Dobyns, William B; Mikati, Mohamed A; İncecik, Faruk; Azam, Matloob; Borgatti, Renato; Romaniello, Romina; Boustany, Rose-Mary; Clericuzio, Carol L; D'Arrigo, Stefano; Strømme, Petter; Boltshauser, Eugen; Stanzial, Franco; Mirabelli-Badenier, Marisol; Moroni, Isabella; Bertini, Enrico; Emma, Francesco; Steinlin, Maja; Hildebrandt, Friedhelm; Johnson, Colin A; Freilinger, Michael; Vaux, Keith K; Gabriel, Stacey B; Aza-Blanc, Pedro; Heynen-Genel, Susanne; Ideker, Trey; Dynlacht, Brian D; Lee, Ji Eun; Valente, Enza Maria; Kim, Joon; Gleeson, Joseph G

2015-01-01

Defective primary ciliogenesis or cilium stability forms the basis of human ciliopathies, including Joubert syndrome (JS), with defective cerebellar vermis development. We performed a high-content genome-wide small interfering RNA (siRNA) screen to identify genes regulating ciliogenesis as candidates for JS. We analyzed results with a supervised-learning approach, using SYSCILIA gold standard, Cildb3.0, a centriole siRNA screen and the GTex project, identifying 591 likely candidates. Intersection of this data with whole exome results from 145 individuals with unexplained JS identified six families with predominantly compound heterozygous mutations in KIAA0586. A c.428del base deletion in 0.1% of the general population was found in trans with a second mutation in an additional set of 9 of 163 unexplained JS patients. KIAA0586 is an orthologue of chick Talpid3, required for ciliogenesis and Sonic hedgehog signaling. Our results uncover a relatively high frequency cause for JS and contribute a list of candidates for future gene discoveries in ciliopathies. DOI: http://dx.doi.org/10.7554/eLife.06602.001 PMID:26026149

Use of internal scintillator radioactivity to calibrate DOI function of a PET detector with a dual-ended-scintillator readout

PubMed Central

Bircher, Chad; Shao, Yiping

2012-01-01

Purpose: Positron emission tomography (PET) detectors that use a dual-ended-scintillator readout to measure depth-of-interaction (DOI) must have an accurate DOI function to provide the relationship between DOI and signal ratios to be used for detector calibration and recalibration. In a previous study, the authors used a novel and simple method to accurately and quickly measure DOI function by irradiating the detector with an external uniform flood source; however, as a practical concern, implementing external uniform flood sources in an assembled PET system is technically challenging and expensive. In the current study, therefore, the authors investigated whether the same method could be used to acquire DOI function from scintillator-generated (i.e., internal) radiation. The authors also developed a method for calibrating the energy scale necessary to select the events within the desired energy window. Methods: The authors measured the DOI function of a PET detector with lutetium yttrium orthosilicate (LYSO) scintillators. Radiation events originating from the scintillators’ internal Lu-176 beta decay were used to measure DOI functions which were then compared with those measured from both an external uniform flood source and an electronically collimated external point source. The authors conducted these studies with several scintillators of differing geometries (1.5 × 1.5 and 2.0 × 2.0 mm2 cross-section area and 20, 30, and 40 mm length) and various surface finishes (mirror-finishing, saw-cut rough, and other finishes in between), and in a prototype array. Results: All measured results using internal and external radiation sources showed excellent agreement in DOI function measurement. The mean difference among DOI values for all scintillators measured from internal and external radiation sources was less than 1.0 mm for different scintillator geometries and various surface finishes. Conclusions: The internal radioactivity of LYSO scintillators can be

Use of internal scintillator radioactivity to calibrate DOI function of a PET detector with a dual-ended-scintillator readout.

PubMed

Bircher, Chad; Shao, Yiping

2012-02-01

Positron emission tomography (PET) detectors that use a dual-ended-scintillator readout to measure depth-of-interaction (DOI) must have an accurate DOI function to provide the relationship between DOI and signal ratios to be used for detector calibration and recalibration. In a previous study, the authors used a novel and simple method to accurately and quickly measure DOI function by irradiating the detector with an external uniform flood source; however, as a practical concern, implementing external uniform flood sources in an assembled PET system is technically challenging and expensive. In the current study, therefore, the authors investigated whether the same method could be used to acquire DOI function from scintillator-generated (i.e., internal) radiation. The authors also developed a method for calibrating the energy scale necessary to select the events within the desired energy window. The authors measured the DOI function of a PET detector with lutetium yttrium orthosilicate (LYSO) scintillators. Radiation events originating from the scintillators' internal Lu-176 beta decay were used to measure DOI functions which were then compared with those measured from both an external uniform flood source and an electronically collimated external point source. The authors conducted these studies with several scintillators of differing geometries (1.5 × 1.5 and 2.0 × 2.0 mm(2) cross-section area and 20, 30, and 40 mm length) and various surface finishes (mirror-finishing, saw-cut rough, and other finishes in between), and in a prototype array. All measured results using internal and external radiation sources showed excellent agreement in DOI function measurement. The mean difference among DOI values for all scintillators measured from internal and external radiation sources was less than 1.0 mm for different scintillator geometries and various surface finishes. The internal radioactivity of LYSO scintillators can be used to accurately measure DOI function

Use of internal scintillator radioactivity to calibrate DOI function of a PET detector with a dual-ended-scintillator readout

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bircher, Chad; Shao Yiping

Purpose: Positron emission tomography (PET) detectors that use a dual-ended-scintillator readout to measure depth-of-interaction (DOI) must have an accurate DOI function to provide the relationship between DOI and signal ratios to be used for detector calibration and recalibration. In a previous study, the authors used a novel and simple method to accurately and quickly measure DOI function by irradiating the detector with an external uniform flood source; however, as a practical concern, implementing external uniform flood sources in an assembled PET system is technically challenging and expensive. In the current study, therefore, the authors investigated whether the same method couldmore » be used to acquire DOI function from scintillator-generated (i.e., internal) radiation. The authors also developed a method for calibrating the energy scale necessary to select the events within the desired energy window. Methods: The authors measured the DOI function of a PET detector with lutetium yttrium orthosilicate (LYSO) scintillators. Radiation events originating from the scintillators' internal Lu-176 beta decay were used to measure DOI functions which were then compared with those measured from both an external uniform flood source and an electronically collimated external point source. The authors conducted these studies with several scintillators of differing geometries (1.5 x 1.5 and 2.0 x 2.0 mm{sup 2} cross-section area and 20, 30, and 40 mm length) and various surface finishes (mirror-finishing, saw-cut rough, and other finishes in between), and in a prototype array. Results: All measured results using internal and external radiation sources showed excellent agreement in DOI function measurement. The mean difference among DOI values for all scintillators measured from internal and external radiation sources was less than 1.0 mm for different scintillator geometries and various surface finishes. Conclusions: The internal radioactivity of LYSO scintillators can

Visual object recognition and tracking

NASA Technical Reports Server (NTRS)

Chang, Chu-Yin (Inventor); English, James D. (Inventor); Tardella, Neil M. (Inventor)

2010-01-01

This invention describes a method for identifying and tracking an object from two-dimensional data pictorially representing said object by an object-tracking system through processing said two-dimensional data using at least one tracker-identifier belonging to the object-tracking system for providing an output signal containing: a) a type of the object, and/or b) a position or an orientation of the object in three-dimensions, and/or c) an articulation or a shape change of said object in said three dimensions.

43 CFR 2.2 - What is DOI's policy regarding release of records under the FOIA?

Code of Federal Regulations, 2012 CFR

2012-10-01

... 43 Public Lands: Interior 1 2012-10-01 2011-10-01 true What is DOI's policy regarding release of records under the FOIA? 2.2 Section 2.2 Public Lands: Interior Office of the Secretary of the Interior RECORDS AND TESTIMONY; FREEDOM OF INFORMATION ACT General Information § 2.2 What is DOI's policy regarding...

43 CFR 2.2 - What is DOI's policy regarding release of records under the FOIA?

Code of Federal Regulations, 2011 CFR

2011-10-01

... 43 Public Lands: Interior 1 2011-10-01 2011-10-01 false What is DOI's policy regarding release of records under the FOIA? 2.2 Section 2.2 Public Lands: Interior Office of the Secretary of the Interior RECORDS AND TESTIMONY; FREEDOM OF INFORMATION ACT General Information § 2.2 What is DOI's policy regarding...

30 CFR 250.1002 - Design requirements for DOI pipelines.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 30 Mineral Resources 2 2011-07-01 2011-07-01 false Design requirements for DOI pipelines. 250.1002 Section 250.1002 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, REGULATION, AND ENFORCEMENT... ratings based on stresses for pipe of the same or equivalent material. The actual bursting strength of the...

Demonstrating the value of publishing open data by linking DOI-based citations of source datasets to uses in research and policy

NASA Astrophysics Data System (ADS)

Copas, K.; Legind, J. K.; Hahn, A.; Braak, K.; Høftt, M.; Noesgaard, D.; Robertson, T.; Méndez Hernández, F.; Schigel, D.; Ko, C.

2017-12-01

GBIF—the Global Biodiversity Information Facility—has recently demonstrated a system that tracks publications back to individual datasets, giving data providers demonstrable evidence of the benefit and utility of sharing data to support an array of scholarly topics and practical applications. GBIF is an open-data network and research infrastructure funded by the world's governments. Its community consists of more than 90 formal participants and almost 1,000 data-publishing institutions, which currently make tens of thousands of datasets containing nearly 800 million species occurrence records freely and publicly available for discovery, use and reuse across a wide range of biodiversity-related research and policy investigations. Starting in 2015 with the help of DataONE, GBIF introduced DOIs as persistent identifiers for the datasets shared through its network. This enhancement soon extended to the assignment of DOIs to user downloads from GBIF.org, which typically filter the available records with a variety of taxonomic, geographic, temporal and other search terms. Despite the lack of widely accepted standards for citing data among researchers and publications, this technical infrastructure is beginning to take hold and support open, transparent, persistent and repeatable use and reuse of species occurrence data. These `download DOIs' provide canonical references for the search results researchers process and use in peer-reviewed articles—a practice GBIF encourages by confirming new DOIs with each download and offering guidelines on citation. GBIF has recently started linking these citation results back to dataset and publisher pages, offering more consistent, traceable evidence of the value of sharing data to support others' research. GBIF's experience may be a useful model for other repositories to follow.

30 CFR 250.1002 - Design requirements for DOI pipelines.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 30 Mineral Resources 2 2010-07-01 2010-07-01 false Design requirements for DOI pipelines. 250.1002 Section 250.1002 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF THE INTERIOR OFFSHORE OIL... stresses for pipe of the same or equivalent material. The actual bursting strength of the fitting shall at...

Object-Based Classification as an Alternative Approach to the Traditional Pixel-Based Classification to Identify Potential Habitat of the Grasshopper Sparrow

NASA Astrophysics Data System (ADS)

Jobin, Benoît; Labrecque, Sandra; Grenier, Marcelle; Falardeau, Gilles

2008-01-01

The traditional method of identifying wildlife habitat distribution over large regions consists of pixel-based classification of satellite images into a suite of habitat classes used to select suitable habitat patches. Object-based classification is a new method that can achieve the same objective based on the segmentation of spectral bands of the image creating homogeneous polygons with regard to spatial or spectral characteristics. The segmentation algorithm does not solely rely on the single pixel value, but also on shape, texture, and pixel spatial continuity. The object-based classification is a knowledge base process where an interpretation key is developed using ground control points and objects are assigned to specific classes according to threshold values of determined spectral and/or spatial attributes. We developed a model using the eCognition software to identify suitable habitats for the Grasshopper Sparrow, a rare and declining species found in southwestern Québec. The model was developed in a region with known breeding sites and applied on other images covering adjacent regions where potential breeding habitats may be present. We were successful in locating potential habitats in areas where dairy farming prevailed but failed in an adjacent region covered by a distinct Landsat scene and dominated by annual crops. We discuss the added value of this method, such as the possibility to use the contextual information associated to objects and the ability to eliminate unsuitable areas in the segmentation and land cover classification processes, as well as technical and logistical constraints. A series of recommendations on the use of this method and on conservation issues of Grasshopper Sparrow habitat is also provided.

ACHP | News | ACHP Member Wins DOI Historic Preservation Award

Science.gov Websites

ACHP Member Wins DOI Historic Preservation Award WASHINGTON, D.C.- Secretary of the Interior Ken Salazar honored four government and tribal employees with the annual Secretary of the Interior Historic innovative design and layout of Randolph AFB has not been significantly altered and it retains an exceptional

The Delphi Technique in Identifying Learning Objectives for the Development of Science, Technology and Society Modules for Palestinian Ninth Grade Science Curriculum

NASA Astrophysics Data System (ADS)

Abualrob, Marwan M. A.; Gnanamalar Sarojini Daniel, Esther

2013-10-01

This article outlines how learning objectives based upon science, technology and society (STS) elements for Palestinian ninth grade science textbooks were identified, which was part of a bigger study to establish an STS foundation in the ninth grade science curriculum in Palestine. First, an initial list of STS elements was determined. Second, using this list, ninth grade science textbooks and curriculum document contents were analyzed. Third, based on this content analysis, a possible list of 71 learning objectives for the integration of STS elements was prepared. This list of learning objectives was refined by using a two-round Delphi technique. The Delphi study was used to rate and to determine the consensus regarding which items (i.e. learning objectives for STS in the ninth grade science textbooks in Palestine) are to be accepted for inclusion. The results revealed that of the initial 71 objectives in round one, 59 objectives within round two had a mean score of 5.683 or higher, which indicated that the learning objectives could be included in the development of STS modules for ninth grade science in Palestine.

STS-87 Mission Specialist Doi with EVA coordinator Laws participates in the CEIT for his mission

NASA Technical Reports Server (NTRS)

1997-01-01

STS-87 Mission Specialist Takao Doi , Ph.D., of the National Space Development Agency of Japan, participates in the Crew Equipment Integration Test (CEIT) at Kennedy Space Center (KSC). Glenda Laws, the extravehicular activity (EVA) coordinator, Johnson Space Center, stands behind Dr. Doi. The CEIT gives astronauts an opportunity to get a hands-on look at the payloads with which they will be working on-orbit. STS-87 will be the fourth United States Microgravity Payload and flight of the Spartan-201 deployable satellite. During the mission, Dr. Doi will be the first Japanese astronaut to perform a spacewalk. STS- 87 is scheduled for a Nov. 19 liftoff from KSC.

Trajectory Recognition as the Basis for Object Individuation: A Functional Model of Object File Instantiation and Object-Token Encoding

PubMed Central

Fields, Chris

2011-01-01

The perception of persisting visual objects is mediated by transient intermediate representations, object files, that are instantiated in response to some, but not all, visual trajectories. The standard object file concept does not, however, provide a mechanism sufficient to account for all experimental data on visual object persistence, object tracking, and the ability to perceive spatially disconnected stimuli as continuously existing objects. Based on relevant anatomical, functional, and developmental data, a functional model is constructed that bases visual object individuation on the recognition of temporal sequences of apparent center-of-mass positions that are specifically identified as trajectories by dedicated “trajectory recognition networks” downstream of the medial–temporal motion-detection area. This model is shown to account for a wide range of data, and to generate a variety of testable predictions. Individual differences in the recognition, abstraction, and encoding of trajectory information are expected to generate distinct object persistence judgments and object recognition abilities. Dominance of trajectory information over feature information in stored object tokens during early infancy, in particular, is expected to disrupt the ability to re-identify human and other individuals across perceptual episodes, and lead to developmental outcomes with characteristics of autism spectrum disorders. PMID:21716599

The DIS, the CODD, IGSNs and DOIs: Tools you need to succeed with your ocean and continental scientific drilling project

NASA Astrophysics Data System (ADS)

Gorgas, Thomas; Conze, Ronald; Lorenz, Henning; Elger, Kirsten; Ulbricht, Damian; Wilkens, Roy; Lyle, Mitchell; Westerhold, Thomas; Drury, Anna Joy; Tian, Jun; Hahn, Annette

2017-04-01

Scientific ocean drilling over the past >40 years and corresponding efforts on land (by now for more than >20 years) has led to the accumulation of an enormous amount of valuable petrophysical, geochemical, biological and geophysical data obtained through laboratory and field experiments across a multitude of scale-and time dimensions. Such data can be utilized comprehensively in a holistic fashion, and thereby provide base toward an enhanced "Core-Log-Integration", modeling small-scale basin processes to large-scale Earth phenomena, while also storing and managing all relevant information in an "Open Access" fashion. Since the early 1990's members of our team have acquired and measured a large dataset of physical and geochemical properties representing both terrestrial and marine geological environments. This dataset cover a variety of both macro-to-microscale dimensions, and thereby allowing this type of interdisciplinary data examination. Over time, data management and processing tools have been developed and were recently merged with modern data publishing methods, which allow identifying and tracking data and associated publications in a trackable and concise manner. Our current presentation summarizes an important part of the value chain in geosciences, comprising: 1) The state-of-the-art in data management for continental and lake drilling projects performed with and through ICDP's Drilling Information System (DIS). 2) The CODD (Code for Ocean Drilling Data) as numerical-based, programmable data processing toolbox and applicable for both continental and marine drilling projects. 3) The implementation of Persistent Identifiers, such as the International Geo Sample Number (IGSN) to identify and track sample material as part of Digital-Object-Identifier (DOI)-tagged operation reports and research publications. 4) A list of contacts provided for scientists with an interest in learning and applying methods and techniques we offer in form of basic and advanced

41 CFR 102-75.665 - What happens after the disposal agency receives the assignment recommendation from DOI?

Code of Federal Regulations, 2010 CFR

2010-07-01

... disposal agency receives the assignment recommendation from DOI? 102-75.665 Section 102-75.665 Public Contracts and Property Management Federal Property Management Regulations System (Continued) FEDERAL... assignment recommendation from DOI? If, after considering other uses for the property, the disposal agency...

41 CFR 102-75.640 - When must DOI notify the disposal agency that an eligible applicant is interested in acquiring...

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false When must DOI notify the... Disposal Property for Use As Public Park Or Recreation Areas § 102-75.640 When must DOI notify the disposal agency that an eligible applicant is interested in acquiring the property? DOI must notify the disposal...

41 CFR 102-75.660 - What happens if DOI does not approve any applications or does not submit an assignment...

Code of Federal Regulations, 2011 CFR

2011-01-01

... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false What happens if DOI does... Disposal Property for Use As Public Park Or Recreation Areas § 102-75.660 What happens if DOI does not approve any applications or does not submit an assignment recommendation? If DOI does not approve any...

41 CFR 102-75.640 - When must DOI notify the disposal agency that an eligible applicant is interested in acquiring...

Code of Federal Regulations, 2011 CFR

2011-01-01

... 41 Public Contracts and Property Management 3 2011-01-01 2011-01-01 false When must DOI notify the... Disposal Property for Use As Public Park Or Recreation Areas § 102-75.640 When must DOI notify the disposal agency that an eligible applicant is interested in acquiring the property? DOI must notify the disposal...

25 CFR 900.208 - How are non-medical related tort claims and lawsuits filed for DOI?

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false How are non-medical related tort claims and lawsuits filed for DOI? 900.208 Section 900.208 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR, AND... Related Claims § 900.208 How are non-medical related tort claims and lawsuits filed for DOI? Non-medical...

25 CFR 900.208 - How are non-medical related tort claims and lawsuits filed for DOI?

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false How are non-medical related tort claims and lawsuits filed for DOI? 900.208 Section 900.208 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR, AND... Related Claims § 900.208 How are non-medical related tort claims and lawsuits filed for DOI? Non-medical...

A Method for Identifying Prevalent Chemical Combinations in the U.S. Population

PubMed Central

Wambaugh, John F.; Ring, Caroline L.; Tornero-Velez, Rogelio; Setzer, R. Woodrow

2017-01-01

Background: Through the food and water they ingest, the air they breathe, and the consumer products with which they interact at home and at work, humans are exposed to tens of thousands of chemicals, many of which have not been evaluated to determine their potential toxicities. Furthermore, while current chemical testing tends to focus on individual chemicals, the exposures that people actually experience involve mixtures of chemicals. Unfortunately, the number of mixtures that can be formed from the thousands of environmental chemicals is enormous, and testing all of them would be impossible. Objectives: We seek to develop and demonstrate a method for identifying those mixtures that are most prevalent in humans. Methods: We applied frequent itemset mining, a technique traditionally used for market basket analysis, to biomonitoring data from the 2009–2010 cycle of the continuous National Health and Nutrition Examination Survey (NHANES) to identify combinations of chemicals that frequently co-occur in people. Results: We identified 90 chemical combinations consisting of relatively few chemicals that occur in at least 30% of the U.S. population, as well as three supercombinations consisting of relatively many chemicals that occur in a small but nonnegligible proportion of the U.S. population. Conclusions: We demonstrated how FIM can be used in conjunction with biomonitoring data to narrow a large number of possible chemical combinations down to a smaller set of prevalent chemical combinations. https://doi.org/10.1289/EHP1265 PMID:28858827

STS-87 Mission Specialist Doi and his wife pose at LC 39B

NASA Technical Reports Server (NTRS)

1997-01-01

STS-87 Mission Specialist Takao Doi, Ph.D., of the National Space Development Agency of Japan poses with his wife, Hitomi Doi, in front of Kennedy Space Center's Launch Pad 39B during final prelaunch activities leading up to the scheduled Nov. 19 liftoff. The other STS-87 crew members are Commander Kevin Kregel; Pilot Steven Lindsey; Mission Specialists Kalpana Chawla, Ph.D., and Winston Scott; and Payload Specialist Leonid Kadenyuk of the National Space Agency of Ukraine. STS-87 will be the fourth flight of the United States Microgravity Payload and the Spartan- 201 deployable satellite.

USMP-4 MGBX ELF, Doi and Lindsey with glovebox experiment

NASA Image and Video Library

1997-11-29

STS087-330-009 (19 November – 5 December 1997) --- Astronauts Takao Doi (left) and Steven W. Lindsey check out the Enclosed Laminar Flames (ELF) experiment on the mid-deck of the Earth-orbiting Space Shuttle Columbia. ELF has been designed to examine the effect of different air flow velocities on the stability of laminar (non-turbulent) flames. Enclosed laminar flames are commonly found in combustion systems such as power plant and gas turbine combustors, and jet engine afterburners. It is hoped that results of this investigation may help to optimize the performance of industrial combustors, including pollutant emissions and heat transfer. The microgravity environment of space makes a perfect setting for a laboratory involving combustion, an activity that creates convection in normal gravity. In microgravity, scientists can study subtle processes ordinarily masked by the effects of gravity. Doi is an international mission specialist representing Japan's National Space Development Agency (NASDA) and Lindsey is the pilot. Both are alumni of NASA's 1995 class of Astronaut Candidates (ASCAN).

Using a binaural biomimetic array to identify bottom objects ensonified by echolocating dolphins

USGS Publications Warehouse

Heiweg, D.A.; Moore, P.W.; Martin, S.W.; Dankiewicz, L.A.

2006-01-01

The development of a unique dolphin biomimetic sonar produced data that were used to study signal processing methods for object identification. Echoes from four metallic objects proud on the bottom, and a substrate-only condition, were generated by bottlenose dolphins trained to ensonify the targets in very shallow water. Using the two-element ('binaural') receive array, object echo spectra were collected and submitted for identification to four neural network architectures. Identification accuracy was evaluated over two receive array configurations, and five signal processing schemes. The four neural networks included backpropagation, learning vector quantization, genetic learning and probabilistic network architectures. The processing schemes included four methods that capitalized on the binaural data, plus a monaural benchmark process. All the schemes resulted in above-chance identification accuracy when applied to learning vector quantization and backpropagation. Beam-forming or concatenation of spectra from both receive elements outperformed the monaural benchmark, with higher sensitivity and lower bias. Ultimately, best object identification performance was achieved by the learning vector quantization network supplied with beam-formed data. The advantages of multi-element signal processing for object identification are clearly demonstrated in this development of a first-ever dolphin biomimetic sonar. ?? 2006 IOP Publishing Ltd.

5-HT2A serotonin receptor agonist DOI alleviates cytotoxicity in neuroblastoma cells: role of the ERK pathway.

PubMed

Marinova, Zoya; Walitza, Susanne; Grünblatt, Edna

2013-07-01

Disturbances of serotonergic signaling, including the serotonin 2A (5-HT2A) receptor, have been implicated in neuropsychiatric and neurodegenerative disorders. The aim of the present study was to characterize the effect of a 5-HT2A receptor agonist on cytotoxicity in a neuronal cell line and address the involved mechanism. HTR2A mRNA and protein expression in human neuroblastoma SK-N-SH cells was confirmed. Cells were subjected to serum deprivation and cell viability was monitored continuously with xCELLigence. In a dose-response study the 5-HT2A agonist (±)-2,5-dimethoxy-4-iodoamphetamine hydrochloride (DOI) (25 nM to 5 μM) protected against serum deprivation cytotoxicity. The selective 5-HT2A receptor antagonist MDL 11,939, the general protein tyrosine kinase inhibitor genistein, and the extracellular signal-regulated kinase (ERK) pathway MEK inhibitor U0126, all attenuated DOI's protective effect. An antibody array suggested that 1 μM DOI affected phosphorylation of several tyrosine kinases. Western blot further confirmed that DOI transiently increased ERK phosphorylation, indicating its activation. Finally, protective concentrations of DOI increased cellular mitochondrial mass, an effect prevented by pretreatment with U0126. In conclusion, our results suggest that DOI protects SK-N-SH cells against serum deprivation through ERK pathway activation. They imply 5-HT2A receptor modulation as a potential target for neuroprotection. Copyright © 2013 Elsevier Inc. All rights reserved.

Relaxation spectra of binary blends: Extension of the Doi-Edwards theory

NASA Astrophysics Data System (ADS)

Tchesnokov, M. A.; Molenaar, J.; Slot, J. J. M.; Stepanyan, R.

2007-10-01

A molecular model is presented which allows the calculation of the stress relaxation function G for binary blends consisting of two monodisperse samples with arbitrary molecular weights. It extends the Doi-Edwards reptation theory (Doi M. and Edwards S. F., The Theory of Polymer Dynamics (Oxford Press, New York) 1986) to highly polydisperse melts by including constraint release (CR) and thermal fluctuations (CLF), yet making use of the same input parameters. The model reveals an explicit nonlinear dependence of CR frequency in the blend on the blend's molecular weight distribution (MWD). It provides an alternative way to quantify polydisperse systems compared to the widely used "double-reptation" theories. The results of the present model are in a good agreement with the experimental data given in Rubinstein M. and Colby R. H., J. Chem. Phys., 89 (1988) 5291.

2 CFR 1401.335 - Whom in the DOI does a recipient other than an individual notify about a criminal drug conviction?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Whom in the DOI does a recipient other than... Individuals § 1401.335 Whom in the DOI does a recipient other than an individual notify about a criminal drug conviction? The DOI is not designating a central location for the receipt of these reports. Therefore you...

2 CFR 1401.401 - Whom in the DOI does a recipient who is an individual notify about a criminal drug conviction?

Code of Federal Regulations, 2011 CFR

2011-01-01

... 2 Grants and Agreements 1 2011-01-01 2011-01-01 false Whom in the DOI does a recipient who is an individual notify about a criminal drug conviction? 1401.401 Section 1401.401 Grants and Agreements Federal... Whom in the DOI does a recipient who is an individual notify about a criminal drug conviction? The DOI...

Quantification of Impervious Surfaces Along the Wasatch Front, Utah: AN Object-Based Image Analysis Approach to Identifying AN Indicator for Wetland Stress

NASA Astrophysics Data System (ADS)

Leydsman-McGinty, E. I.; Ramsey, R. D.; McGinty, C.

2013-12-01

The Remote Sensing/GIS Laboratory at Utah State University, in cooperation with the United States Environmental Protection Agency, is quantifying impervious surfaces for three watershed sub-basins in Utah. The primary objective of developing watershed-scale quantifications of impervious surfaces is to provide an indicator of potential impacts to wetlands that occur within the Wasatch Front and along the Great Salt Lake. A geospatial layer of impervious surfaces can assist state agencies involved with Utah's Wetlands Program Plan (WPP) in understanding the impacts of impervious surfaces on wetlands, as well as support them in carrying out goals and actions identified in the WPP. The three watershed sub-basins, Lower Bear-Malad, Lower Weber, and Jordan, span the highly urbanized Wasatch Front and are consistent with focal areas in need of wetland monitoring and assessment as identified in Utah's WPP. Geospatial layers of impervious surface currently exist in the form of national and regional land cover datasets; however, these datasets are too coarse to be utilized in fine-scale analyses. In addition, the pixel-based image processing techniques used to develop these coarse datasets have proven insufficient in smaller scale or detailed studies, particularly when applied to high-resolution satellite imagery or aerial photography. Therefore, object-based image analysis techniques are being implemented to develop the geospatial layer of impervious surfaces. Object-based image analysis techniques employ a combination of both geospatial and image processing methods to extract meaningful information from high-resolution imagery. Spectral, spatial, textural, and contextual information is used to group pixels into image objects and then subsequently used to develop rule sets for image classification. eCognition, an object-based image analysis software program, is being utilized in conjunction with one-meter resolution National Agriculture Imagery Program (NAIP) aerial

The efficacy of three objective systems for identifying beef cuts that can be guaranteed tender.

PubMed

Wheeler, T L; Vote, D; Leheska, J M; Shackelford, S D; Belk, K E; Wulf, D M; Gwartney, B L; Koohmaraie, M

2002-12-01

The objective of this study was to determine the accuracy of three objective systems (prototype BeefCam, colorimeter, and slice shear force) for identifying guaranteed tender beef. In Phase I, 308 carcasses (105 Top Choice, 101 Low Choice, and 102 Select) from two commercial plants were tested. In Phase II, 400 carcasses (200 rolled USDA Select and 200 rolled USDA Choice) from one commercial plant were tested. The three systems were evaluated based on progressive certification of the longissimus as "tender" in 10% increments (the best 10, 20, 30%, etc., certified as "tender" by each technology; 100% certification would mean no sorting for tenderness). In Phase I, the error (percentage of carcasses certified as tender that had Warner-Bratzler shear force of > or = 5 kg at 14 d postmortem) for 100% certification using all carcasses was 14.1%. All certification levels up to 80% (slice shear force) and up to 70% (colorimeter) had less error (P < 0.05) than 100% certification. Errors in all levels of certification by prototype BeefCam (13.8 to 9.7%) were not different (P > 0.05) from 100% certification. In Phase I, the error for 100% certification for USDA Select carcasses was 30.7%. For Select carcasses, all slice shear force certification levels up to 60% (0 to 14.8%) had less error (P < 0.05) than 100% certification. For Select carcasses, errors in all levels of certification by colorimeter (20.0 to 29.6%) and by BeefCam (27.5 to 31.4%) were not different (P > 0.05) from 100% certification. In Phase II, the error for 100% certification for all carcasses was 9.3%. For all levels of slice shear force certification less than 90% (for all carcasses) or less than 80% (Select carcasses), errors in tenderness certification were less than (P < 0.05) for 100% certification. In Phase II, for all carcasses or Select carcasses, colorimeter and prototype BeefCam certifications did not significantly reduce errors (P > 0.05) compared to 100% certification. Thus, the direct measure

Investigating the impact of atmospheric blocking on temperature extremes across Europe using an objective index

NASA Astrophysics Data System (ADS)

Brunner, Lukas; Steiner, Andrea; Sillmann, Jana

2017-04-01

Atmospheric blocking is a key contributor to European temperature extremes. It leads to stable, long-lasting weather patterns, which favor the development of cold and warm spells. The link between blocking and such temperature extremes differs significantly across Europe. In northern Europe a majority of warm spells are connected to blocking, while cold spells are suppressed during blocked conditions. In southern Europe the opposite picture arises with most cold spells occurring during blocking and warm spells suppressed. Building on earlier work by Brunner et al. (2017) this study aims at a better understanding of the connection between blocking and temperature extremes in Europe. We investigate cold and warm spells with and without blocking in observations from the European daily high-resolution gridded dataset (E-OBS) from 1979 to 2015. We use an objective extreme index (Russo et al. 2015) to identify and compare cold and warm spells across Europe. Our work is lead by the main question: Are cold/warm spells coinciding with blocking different from cold/warm spells during unblocked conditions in regard to duration, extend, or amplitude? Here we present our research question and the study setup, and show first results of our analysis on European temperature extremes. Brunner, L., G. Hegerl, and A. Steiner (2017): Connecting Atmospheric Blocking to European Temperature Extremes in Spring. J. Climate, 30, 585-594, doi: 10.1175/JCLI-D-16-0518.1. Russo, S., J. Sillmann, and E. M. Fischer (2015): Top ten European heatwaves since 1950 and their occurrence in the coming decades. Environ. Res. Lett. 10.12, S. 124003. doi: 10.1088/1748-9326/10/12/124003.

Persistent Identifiers for Dutch cultural heritage institutions

NASA Astrophysics Data System (ADS)

Ras, Marcel; Kruithof, Gijsbert

2016-04-01

Over the past years, more and more collections belonging to archives, libraries, media, museums, and knowledge institutes are being digitised and made available online. These are exciting times for ALM institutions. They are realising that, in the information society, their collections are goldmines. Unfortunately most heritage institutions in the Netherlands do not yet meet the basic preconditions for long-term availability of their collections. The digital objects often have no long lasting fixed reference yet. URL's and web addresses change. Some digital objects that were referenced in Europeana and other portals can no longer be found. References in scientific articles have a very short life span, which is damaging for scholarly research. In 2015, the Dutch Digital Heritage Network (NDE) has started a two-year work program to co-ordinate existing initiatives in order to improve the (long-term) accessibility of the Dutch digital heritage for a wide range of users, anytime, anyplace. The Digital Heritage Network is a partnership established on the initiative of the Ministry of Education, Culture and Science. The members of the NDE are large, national institutions that strive to professionally preserve and manage digital data, e.g. the National Library, The Netherlands Institute for Sound and Vision, the Netherlands Cultural Heritage Agency, the Royal Netherlands Academy of Arts and Sciences, the National Archive of the Netherlands and the DEN Foundation, and a growing number of associations and individuals both within and outside the heritage sector. By means of three work programmes the goals of the Network should be accomplished and improve the visibility, the usability and the sustainability of digital heritage. Each programme contains of a set of projects. Within the sustainability program a project on creating a model for persistent identifiers is taking place. The main goals of the project are (1) raise awareness among cultural heritage institutions on the

Identification of uncommon objects in containers

DOEpatents

Bremer, Peer-Timo; Kim, Hyojin; Thiagarajan, Jayaraman J.

2017-09-12

A system for identifying in an image an object that is commonly found in a collection of images and for identifying a portion of an image that represents an object based on a consensus analysis of segmentations of the image. The system collects images of containers that contain objects for generating a collection of common objects within the containers. To process the images, the system generates a segmentation of each image. The image analysis system may also generate multiple segmentations for each image by introducing variations in the selection of voxels to be merged into a segment. The system then generates clusters of the segments based on similarity among the segments. Each cluster represents a common object found in the containers. Once the clustering is complete, the system may be used to identify common objects in images of new containers based on similarity between segments of images and the clusters.

The Delphi Technique in Identifying Learning Objectives for the Development of Science, Technology and Society Modules for Palestinian Ninth Grade Science Curriculum

ERIC Educational Resources Information Center

Abualrob, Marwan M. A.; Daniel, Esther Gnanamalar Sarojini

2013-01-01

This article outlines how learning objectives based upon science, technology and society (STS) elements for Palestinian ninth grade science textbooks were identified, which was part of a bigger study to establish an STS foundation in the ninth grade science curriculum in Palestine. First, an initial list of STS elements was determined. Second,…

Doi looks through food locker in the MDDK during STS-123 mission

NASA Image and Video Library

2008-03-11

S123-E-005126 (11 March 2008) --- Japan Aerospace Exploration Agency (JAXA) astronaut Takao Doi, STS-123 mission specialist, prepares a meal at the galley on the middeck of Space Shuttle Endeavour late in flight day one activities.

Side readout of long scintillation crystal elements with digital SiPM for TOF-DOI PET.

PubMed

Yeom, Jung Yeol; Vinke, Ruud; Levin, Craig S

2014-12-01

Side readout of scintillation light from crystal elements in positron emission tomography (PET) is an alternative to conventional end-readout configurations, with the benefit of being able to provide accurate depth-of-interaction (DOI) information and good energy resolution while achieving excellent timing resolution required for time-of-flight PET. This paper explores different readout geometries of scintillation crystal elements with the goal of achieving a detector that simultaneously achieves excellent timing resolution, energy resolution, spatial resolution, and photon sensitivity. The performance of discrete LYSO scintillation elements of different lengths read out from the end/side with digital silicon photomultipliers (dSiPMs) has been assessed. Compared to 3 × 3 × 20 mm(3) LYSO crystals read out from their ends with a coincidence resolving time (CRT) of 162 ± 6 ps FWHM and saturated energy spectra, a side-readout configuration achieved an excellent CRT of 144 ± 2 ps FWHM after correcting for timing skews within the dSiPM and an energy resolution of 11.8% ± 0.2% without requiring energy saturation correction. Using a maximum likelihood estimation method on individual dSiPM pixel response that corresponds to different 511 keV photon interaction positions, the DOI resolution of this 3 × 3 × 20 mm(3) crystal side-readout configuration was computed to be 0.8 mm FWHM with negligible artifacts at the crystal ends. On the other hand, with smaller 3 × 3 × 5 mm(3) LYSO crystals that can also be tiled/stacked to provide DOI information, a timing resolution of 134 ± 6 ps was attained but produced highly saturated energy spectra. The energy, timing, and DOI resolution information extracted from the side of long scintillation crystal elements coupled to dSiPM have been acquired for the first time. The authors conclude in this proof of concept study that such detector configuration has the potential to enable outstanding detector performance in terms of timing

Side readout of long scintillation crystal elements with digital SiPM for TOF-DOI PET

DOE Office of Scientific and Technical Information (OSTI.GOV)

Yeom, Jung Yeol, E-mail: yeomjy@kumoh.ac.kr, E-mail: cslevin@stanford.edu; Vinke, Ruud; Levin, Craig S., E-mail: yeomjy@kumoh.ac.kr, E-mail: cslevin@stanford.edu

Purpose: Side readout of scintillation light from crystal elements in positron emission tomography (PET) is an alternative to conventional end-readout configurations, with the benefit of being able to provide accurate depth-of-interaction (DOI) information and good energy resolution while achieving excellent timing resolution required for time-of-flight PET. This paper explores different readout geometries of scintillation crystal elements with the goal of achieving a detector that simultaneously achieves excellent timing resolution, energy resolution, spatial resolution, and photon sensitivity. Methods: The performance of discrete LYSO scintillation elements of different lengths read out from the end/side with digital silicon photomultipliers (dSiPMs) has been assessed.more » Results: Compared to 3 × 3 × 20 mm{sup 3} LYSO crystals read out from their ends with a coincidence resolving time (CRT) of 162 ± 6 ps FWHM and saturated energy spectra, a side-readout configuration achieved an excellent CRT of 144 ± 2 ps FWHM after correcting for timing skews within the dSiPM and an energy resolution of 11.8% ± 0.2% without requiring energy saturation correction. Using a maximum likelihood estimation method on individual dSiPM pixel response that corresponds to different 511 keV photon interaction positions, the DOI resolution of this 3 × 3 × 20 mm{sup 3} crystal side-readout configuration was computed to be 0.8 mm FWHM with negligible artifacts at the crystal ends. On the other hand, with smaller 3 × 3 × 5 mm{sup 3} LYSO crystals that can also be tiled/stacked to provide DOI information, a timing resolution of 134 ± 6 ps was attained but produced highly saturated energy spectra. Conclusions: The energy, timing, and DOI resolution information extracted from the side of long scintillation crystal elements coupled to dSiPM have been acquired for the first time. The authors conclude in this proof of concept study that such detector configuration has the potential to

Visual Priming of Inverted and Rotated Objects

ERIC Educational Resources Information Center

Knowlton, Barbara J.; McAuliffe, Sean P.; Coelho, Chase J.; Hummel, John E.

2009-01-01

Object images are identified more efficiently after prior exposure. Here, the authors investigated shape representations supporting object priming. The dependent measure in all experiments was the minimum exposure duration required to correctly identify an object image in a rapid serial visual presentation stream. Priming was defined as the change…

Intrinsic and contextual features in object recognition.

PubMed

Schlangen, Derrick; Barenholtz, Elan

2015-01-28

The context in which an object is found can facilitate its recognition. Yet, it is not known how effective this contextual information is relative to the object's intrinsic visual features, such as color and shape. To address this, we performed four experiments using rendered scenes with novel objects. In each experiment, participants first performed a visual search task, searching for a uniquely shaped target object whose color and location within the scene was experimentally manipulated. We then tested participants' tendency to use their knowledge of the location and color information in an identification task when the objects' images were degraded due to blurring, thus eliminating the shape information. In Experiment 1, we found that, in the absence of any diagnostic intrinsic features, participants identified objects based purely on their locations within the scene. In Experiment 2, we found that participants combined an intrinsic feature, color, with contextual location in order to uniquely specify an object. In Experiment 3, we found that when an object's color and location information were in conflict, participants identified the object using both sources of information equally. Finally, in Experiment 4, we found that participants used whichever source of information-either color or location-was more statistically reliable in order to identify the target object. Overall, these experiments show that the context in which objects are found can play as important a role as intrinsic features in identifying the objects. © 2015 ARVO.

[Research of Identify Spatial Object Using Spectrum Analysis Technique].

PubMed

Song, Wei; Feng, Shi-qi; Shi, Jing; Xu, Rong; Wang, Gong-chang; Li, Bin-yu; Liu, Yu; Li, Shuang; Cao Rui; Cai, Hong-xing; Zhang, Xi-he; Tan, Yong

2015-06-01

The high precision scattering spectrum of spatial fragment with the minimum brightness of 4.2 and the resolution of 0.5 nm has been observed using spectrum detection technology on the ground. The obvious differences for different types of objects are obtained by the normalizing and discrete rate analysis of the spectral data. Each of normalized multi-frame scattering spectral line shape for rocket debris is identical. However, that is different for lapsed satellites. The discrete rate of the single frame spectrum of normalized space debris for rocket debris ranges from 0.978% to 3.067%, and the difference of oscillation and average value is small. The discrete rate for lapsed satellites ranges from 3.118 4% to 19.472 7%, and the difference of oscillation and average value relatively large. The reason is that the composition of rocket debris is single, while that of the lapsed satellites is complex. Therefore, the spectrum detection technology on the ground can be used to the classification of the spatial fragment.

25 CFR 1000.232 - When must DOI respond to a request for reconsideration?

Code of Federal Regulations, 2010 CFR

2010-04-01

... INTERIOR ANNUAL FUNDING AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT Waiver of Regulations § 1000.232 When must DOI respond to a request for...

Scalable persistent identifier systems for dynamic datasets

NASA Astrophysics Data System (ADS)

Golodoniuc, P.; Cox, S. J. D.; Klump, J. F.

2016-12-01

Reliable and persistent identification of objects, whether tangible or not, is essential in information management. Many Internet-based systems have been developed to identify digital data objects, e.g., PURL, LSID, Handle, ARK. These were largely designed for identification of static digital objects. The amount of data made available online has grown exponentially over the last two decades and fine-grained identification of dynamically generated data objects within large datasets using conventional systems (e.g., PURL) has become impractical. We have compared capabilities of various technological solutions to enable resolvability of data objects in dynamic datasets, and developed a dataset-centric approach to resolution of identifiers. This is particularly important in Semantic Linked Data environments where dynamic frequently changing data is delivered live via web services, so registration of individual data objects to obtain identifiers is impractical. We use identifier patterns and pattern hierarchies for identification of data objects, which allows relationships between identifiers to be expressed, and also provides means for resolving a single identifier into multiple forms (i.e. views or representations of an object). The latter can be implemented through (a) HTTP content negotiation, or (b) use of URI querystring parameters. The pattern and hierarchy approach has been implemented in the Linked Data API supporting the United Nations Spatial Data Infrastructure (UNSDI) initiative and later in the implementation of geoscientific data delivery for the Capricorn Distal Footprints project using International Geo Sample Numbers (IGSN). This enables flexible resolution of multi-view persistent identifiers and provides a scalable solution for large heterogeneous datasets.

Basic performance of Mg co-doped new scintillator used for TOF-DOI-PET systems

NASA Astrophysics Data System (ADS)

Kobayashi, Takahiro; Yamamoto, Seiichi; Okumura, Satoshi; Yeom, Jung Yeol; Kamada, Kei; Yoshikawa, Akira

2017-01-01

Phoswich depth-of-interaction (DOI) detectors utilizing multiple scintillators with different decay time are a useful device for developing a high spatial resolution, high sensitivity PET scanner. However, in order to apply pulse shape discrimination (PSD), there are not many combinations of scintillators for which phoswich technique can be implemented. Ce doped Gd3Ga3Al2O12 (GFAG) is a recently developed scintillator with a fast decay time. This scintillator is similar to Ce doped Gd3Al2Ga3O12 (GAGG), which is a promising scintillator for PET detector with high light yield. By stacking these scintillators, it may be possible to realize a high spatial resolution and high timing resolution phoswich DOI detector. Such phoswich DOI detector may be applied to time-of-flight (TOF) systems with high timing performance. Therefore, in this study, we tested the basic performance of the new scintillator -GFAG for use in a TOF phoswich detector. The measured decay time of a GFAG element of 2.9 mmx2.9 mmx10 mm in dimension, which was optically coupled to a photomultiplier tube (PMT), was faster (66 ns) than that of same sized GAGG (103 ns). The energy resolution of the GFAG element was 5.7% FWHM which was slightly worse than that of GAGG with 4.9% FWHM for 662 keV gamma photons without saturation correction. Then we assembled the GFAG and the GAGG crystals in the depth direction to form a 20 mm long phoswich element (GFAG/GAGG). By pulse shape analysis, the two types of scintillators were clearly resolved. Measured timing resolution of a pair of opposing GFAG/GAGG phoswich scintillator coupled to Silicon Photomultipliers (Si-PM) was good with coincidence resolving time of 466 ps FWHM. These results indicate that the GFAG combined with GAGG can be a candidate for TOF-DOI-PET systems.

DOI Determination by Rise Time Discrimination in Single-Ended Readout for TOF PET Imaging

PubMed Central

Wiener, R.I.; Surti, S.; Karp, J.S.

2013-01-01

Clinical TOF PET systems achieve detection efficiency using thick crystals, typically of thickness 2–3cm. The resulting dispersion in interaction depths degrades spatial resolution for increasing radial positions due to parallax error. Furthermore, interaction depth dispersion results in time pickoff dispersion and thus in degraded timing resolution, and is therefore of added concern in TOF scanners. Using fast signal digitization, we characterize the timing performance, pulse shape and light output of LaBr3:Ce, CeBr3 and LYSO. Coincidence timing resolution is shown to degrade by ~50ps/cm for scintillator pixels of constant cross section and increasing length. By controlling irradiation depth in a scintillator pixel, we show that DOI-dependence of time pickoff is a significant factor in the loss of timing performance in thick detectors. Using the correlated DOI-dependence of time pickoff and charge collection, we apply a charge-based correction to the time pickoff, obtaining improved coincidence timing resolution of <200ps for a uniform 4×4×30mm3 LaBr3 pixel. In order to obtain both DOI identification and improved timing resolution, we design a two layer LaBr3[5%Ce]/LaBr3[30%Ce] detector of total size 4×4×30mm3, exploiting the dependence of scintillator rise time on [Ce] in LaBr3:Ce. Using signal rise time to determine interaction layer, excellent interaction layer discrimination is achieved, while maintaining coincidence timing resolution of <250ps and energy resolution <7% using a R4998 PMT. Excellent layer separation and timing performance is measured with several other commercially-available TOF photodetectors, demonstrating the practicality of this design. These results indicate the feasibility of rise time discrimination as a technique for measuring event DOI while maintaining sensitivity, timing and energy performance, in a well-known detector architecture. PMID:24403611

DOI Determination by Rise Time Discrimination in Single-Ended Readout for TOF PET Imaging.

PubMed

Wiener, R I; Surti, S; Karp, J S

2013-06-01

Clinical TOF PET systems achieve detection efficiency using thick crystals, typically of thickness 2-3cm. The resulting dispersion in interaction depths degrades spatial resolution for increasing radial positions due to parallax error. Furthermore, interaction depth dispersion results in time pickoff dispersion and thus in degraded timing resolution, and is therefore of added concern in TOF scanners. Using fast signal digitization, we characterize the timing performance, pulse shape and light output of LaBr 3 :Ce, CeBr 3 and LYSO. Coincidence timing resolution is shown to degrade by ~50ps/cm for scintillator pixels of constant cross section and increasing length. By controlling irradiation depth in a scintillator pixel, we show that DOI-dependence of time pickoff is a significant factor in the loss of timing performance in thick detectors. Using the correlated DOI-dependence of time pickoff and charge collection, we apply a charge-based correction to the time pickoff, obtaining improved coincidence timing resolution of <200ps for a uniform 4×4×30mm 3 LaBr 3 pixel. In order to obtain both DOI identification and improved timing resolution, we design a two layer LaBr 3 [5%Ce]/LaBr 3 [30%Ce] detector of total size 4×4×30mm 3 , exploiting the dependence of scintillator rise time on [Ce] in LaBr 3 :Ce. Using signal rise time to determine interaction layer, excellent interaction layer discrimination is achieved, while maintaining coincidence timing resolution of <250ps and energy resolution <7% using a R4998 PMT. Excellent layer separation and timing performance is measured with several other commercially-available TOF photodetectors, demonstrating the practicality of this design. These results indicate the feasibility of rise time discrimination as a technique for measuring event DOI while maintaining sensitivity, timing and energy performance, in a well-known detector architecture.

Identifying mangrove species and their surrounding land use and land cover classes using object-oriented approach with a lacunarity spatial measure

USGS Publications Warehouse

Myint, S.W.; Giri, C.P.; Wang, L.; Zhu, Z.; Gillete, S.C.

2008-01-01

Accurate and reliable information on the spatial distribution of mangrove species is needed for a wide variety of applications, including sustainable management of mangrove forests, conservation and reserve planning, ecological and biogeographical studies, and invasive species management. Remotely sensed data have been used for such purposes with mixed results. Our study employed an object-oriented approach with the use of a lacunarity technique to identify different mangrove species and their surrounding land use and land cover classes in a tsunami-affected area of Thailand using Landsat satellite data. Our results showed that the object-oriented approach with lacunarity-transformed bands is more accurate (over-all accuracy 94.2%; kappa coefficient = 0.91) than traditional per-pixel classifiers (overall accuracy 62.8%; and kappa coefficient = 0.57). Copyright ?? 2008 by Bellwether Publishing, Ltd. All rights reserved.

Perceptual Learning of Object Shape

PubMed Central

Golcu, Doruk; Gilbert, Charles D.

2009-01-01

Recognition of objects is accomplished through the use of cues that depend on internal representations of familiar shapes. We used a paradigm of perceptual learning during visual search to explore what features human observers use to identify objects. Human subjects were trained to search for a target object embedded in an array of distractors, until their performance improved from near-chance levels to over 80% of trials in an object specific manner. We determined the role of specific object components in the recognition of the object as a whole by measuring the transfer of learning from the trained object to other objects sharing components with it. Depending on the geometric relationship of the trained object with untrained objects, transfer to untrained objects was observed. Novel objects that shared a component with the trained object were identified at much higher levels than those that did not, and this could be used as an indicator of which features of the object were important for recognition. Training on an object also transferred to the components of the object when these components were embedded in an array of distractors of similar complexity. These results suggest that objects are not represented in a holistic manner during learning, but that their individual components are encoded. Transfer between objects was not complete, and occurred for more than one component, regardless of how well they distinguish the object from distractors. This suggests that a joint involvement of multiple components was necessary for full performance. PMID:19864574

Doi looks at food packages in the FWD MDDK during Joint Operations

NASA Image and Video Library

2008-03-15

S123-E-006367 (15 March 2008) --- Japan Aerospace Exploration Agency (JAXA) astronaut Takao Doi, STS-123 mission specialists, looks over his choices of beverages and snacks at the galley on the middeck of Space Shuttle Endeavour while docked with the International Space Station.

A Temporal Same-Object Advantage in the Tunnel Effect: Facilitated Change Detection for Persisting Objects

ERIC Educational Resources Information Center

Flombaum, Jonathan I.; Scholl, Brian J.

2006-01-01

Meaningful visual experience requires computations that identify objects as the same persisting individuals over time, motion, occlusion, and featural change. This article explores these computations in the tunnel effect: When an object moves behind an occluder, and then an object later emerges following a consistent trajectory, observers…

Setting objectives for managing Key deer

USGS Publications Warehouse

Diefenbach, Duane R.; Wagner, Tyler; Stauffer, Glenn E.

2014-01-01

The U.S. Fish and Wildlife Service (FWS) is responsible for the protection and management of Key deer (Odocoileus virginianus clavium) because the species is listed as Endangered under the Endangered Species Act (ESA). The purpose of the ESA is to protect and recover imperiled species and the ecosystems upon which they depend. There are a host of actions that could possibly be undertaken to recover the Key deer population, but without a clearly defined problem and stated objectives it can be difficult to compare and evaluate alternative actions. In addition, management goals and the acceptability of alternative management actions are inherently linked to stakeholders, who should be engaged throughout the process of developing a decision framework. The purpose of this project was to engage a representative group of stakeholders to develop a problem statement that captured the management problem the FWS must address with Key deer and identify objectives that, if met, would help solve the problem. In addition, the objectives were organized in a hierarchical manner (i.e., an objectives network) to show how they are linked, and measurable attributes were identified for each objective. We organized a group of people who represented stakeholders interested in and potentially affected by the management of Key deer. These stakeholders included individuals who represented local, state, and federal governments, non-governmental organizations, the general public, and local businesses. This stakeholder group met five full days over the course of an eight-week period to identify objectives that would address the following problem:“As recovery and removal from the Endangered Species list is the purpose of the Endangered Species Act, the U.S. Fish and Wildlife Service needs a management approach that will ensure a sustainable, viable, and healthy Key deer population. Urbanization has affected the behavior and population dynamics of the Key deer and the amount and characteristics

The effect of the sigma-1 receptor selective compound LS-1-137 on the DOI-induced head twitch response in mice.

PubMed

Malik, Maninder; Rangel-Barajas, Claudia; Mach, Robert H; Luedtke, Robert R

2016-09-01

Several receptor mediated pathways have been shown to modulate the murine head twitch response (HTR). However, the role of sigma receptors in the murine (±)-2,5-dimethoxy-4-iodoamphetamine (DOI)-induced HTR has not been previously investigated. We examined the ability of LS-1-137, a novel sigma-1 vs. sigma-2 receptor selective phenylacetamide, to modulate the DOI-induced HTR in DBA/2J mice. We also assessed the in vivo efficacy of reference sigma-1 receptor antagonists and agonists PRE-084 and PPCC. The effect of the sigma-2 receptor selective antagonist RHM-1-86 was also examined. Rotarod analysis was performed to monitor motor coordination after LS-1-137 administration. Radioligand binding techniques were used to determine the affinity of LS-1-137 at 5-HT2A and 5-HT2C receptors. LS-1-137 and the sigma-1 receptor antagonists haloperidol and BD 1047 were able to attenuate a DOI-induced HTR, indicating that LS-1-137 was acting in vivo as a sigma-1 receptor antagonist. LS-1-137 did not compromise rotarod performance within a dose range capable of attenuating the effects of DOI. Radioligand binding studies indicate that LS-1-137 exhibits low affinity binding at both 5-HT2A and 5-HT2C receptors. Based upon the results from these and our previous studies, LS-1-137 is a neuroprotective agent that attenuates the murine DOI-induced HTR independent of activity at 5-HT2 receptor subtypes, D2-like dopamine receptors, sigma-2 receptors and NMDA receptors. LS-1-137 appears to act as a sigma-1 receptor antagonist to inhibit the DOI-induced HTR. Therefore, the DOI-induced HTR can be used to assess the in vivo efficacy of sigma-1 receptor selective compounds. Copyright © 2016. Published by Elsevier Inc.

Tracking target objects orbiting earth using satellite-based telescopes

DOEpatents

De Vries, Willem H; Olivier, Scot S; Pertica, Alexander J

2014-10-14

A system for tracking objects that are in earth orbit via a constellation or network of satellites having imaging devices is provided. An object tracking system includes a ground controller and, for each satellite in the constellation, an onboard controller. The ground controller receives ephemeris information for a target object and directs that ephemeris information be transmitted to the satellites. Each onboard controller receives ephemeris information for a target object, collects images of the target object based on the expected location of the target object at an expected time, identifies actual locations of the target object from the collected images, and identifies a next expected location at a next expected time based on the identified actual locations of the target object. The onboard controller processes the collected image to identify the actual location of the target object and transmits the actual location information to the ground controller.

Scott and Doi conduct tool evaluations during second EVA of STS-87

NASA Image and Video Library

1997-12-03

STS087-341-036 (3 Dec. 1997) --- Backdropped against a dark Earth and a light blue horizon, astronaut Takao Doi (right), international mission specialist representing Japan's National Space Development Agency (NASDA), works with a crane while astronaut Winston E. Scott looks on. This second extravehicular activity (EVA) of the mission continued the evaluation of techniques and hardware to be used in constructing the International Space Station (ISS). Near Scott can be seen the representation of a small Orbital Replacement Unit (ORU) in the grasp of the 156-pound crane operated by Doi. A similar crane could be used to transport various sized ORU’s from translation carts on the exterior of the ISS to various worksites on the truss structure. This view was captured, on 35mm film, by a crew mate in the shirt sleeve environment of the Space Shuttle Columbia's cabin. The SPARTAN-201 satellite is in its stowed position at frame center.

The Near-Earth Object Human Space Flight Accessible Targets Study (NHATS) List of Near-Earth Asteroids: Identifying Potential Targets for Future Exploration

NASA Astrophysics Data System (ADS)

Abell, Paul; Barbee, B. W.; Mink, R. G.; Adamo, D. R.; Alberding, C. M.; Mazanek, D. D.; Johnson, L. N.; Yeomans, D. K.; Chodas, P. W.; Chamberlin, A. B.; Benner, L. A. M.; Drake, B. G.; Friedensen, V. P.

2012-10-01

Introduction: Much attention has recently been focused on human exploration of near-Earth asteroids (NEAs). Detailed planning for deep space exploration and identification of potential NEA targets for human space flight requires selecting objects from the growing list of known NEAs. NASA therefore initiated the Near-Earth Object Human Space Flight Accessible Target Study (NHATS), which uses dynamical trajectory performance constraints to identify potentially accessible NEAs. Accessibility Criteria: Future NASA human space flight capability is being defined while the Orion Multi-Purpose Crew Vehicle and Space Launch System are under development. Velocity change and mission duration are two of the most critical factors in any human spaceflight endeavor, so the most accessible NEAs tend to be those with orbits similar to Earth’s. To be classified as NHATS-compliant, a NEA must offer at least one round-trip trajectory solution satisfying purposely inclusive constraints, including total mission change in velocity ≤ 12 km/s, mission duration ≤ 450 days (with at least 8 days at the NEA), Earth departure between Jan 1, 2015 and Dec 31, 2040, Earth departure C3 ≤ 60 km2/s2, and Earth return atmospheric entry speed ≤ 12 km/s. Monitoring and Updates: The NHATS list of potentially accessible targets is continuously updated as NEAs are discovered and orbit solutions for known NEAs are improved. The current list of accessible NEAs identified as potentially viable for future human exploration under the NHATS criteria is available to the international community via a website maintained by NASA’s NEO Program Office (http://neo.jpl.nasa.gov/nhats/). This website also lists predicted optical and radar observing opportunities for each NHATS-compliant NEA to facilitate acquisition of follow-up observations. Conclusions: This list of NEAs will be useful for analyzing robotic mission opportunities, identifying optimal round trip human space flight trajectories, and

Object-based attention: strength of object representation and attentional guidance.

PubMed

Shomstein, Sarah; Behrmann, Marlene

2008-01-01

Two or more features belonging to a single object are identified more quickly and more accurately than are features belonging to different objects--a finding attributed to sensory enhancement of all features belonging to an attended or selected object. However, several recent studies have suggested that this "single-object advantage" may be a product of probabilistic and configural strategic prioritizations rather than of object-based perceptual enhancement per se, challenging the underlying mechanism that is thought to give rise to object-based attention. In the present article, we further explore constraints on the mechanisms of object-based selection by examining the contribution of the strength of object representations to the single-object advantage. We manipulated factors such as exposure duration (i.e., preview time) and salience of configuration (i.e., objects). Varying preview time changes the magnitude of the object-based effect, so that if there is ample time to establish an object representation (i.e., preview time of 1,000 msec), then both probability and configuration (i.e., objects) guide attentional selection. If, however, insufficient time is provided to establish a robust object-based representation, then only probabilities guide attentional selection. Interestingly, at a short preview time of 200 msec, when the two objects were sufficiently different from each other (i.e., different colors), both configuration and probability guided attention selection. These results suggest that object-based effects can be explained both in terms of strength of object representations (established at longer exposure durations and by pictorial cues) and probabilistic contingencies in the visual environment.

Influence of detector pixel size, TOF resolution and DOI on image quality in MR-compatible whole-body PET.

PubMed

Thoen, Hendrik; Keereman, Vincent; Mollet, Pieter; Van Holen, Roel; Vandenberghe, Stefaan

2013-09-21

The optimization of a whole-body PET system remains a challenging task, as the imaging performance is influenced by a complex interaction of different design parameters. However, it is not always clear which parameters have the largest impact on image quality and are most eligible for optimization. To determine this, we need to be able to assess their influence on image quality. We performed Monte-Carlo simulations of a whole-body PET scanner to predict the influence on image quality of three detector parameters: the TOF resolution, the transverse pixel size and depth-of-interaction (DOI)-correction. The inner diameter of the PET scanner was 65 cm, small enough to allow physical integration into a simultaneous PET-MR system. Point sources were used to evaluate the influence of transverse pixel size and DOI-correction on spatial resolution as function of radial distance. To evaluate the influence on contrast recovery and pixel noise a cylindrical phantom of 35 cm diameter was used, representing a large patient. The phantom contained multiple hot lesions with 5 mm diameter. These lesions were placed at radial distances of 50, 100 and 150 mm from the center of the field-of-view, to be able to study the effects at different radial positions. The non-prewhitening (NPW) observer was used for objective analysis of the detectability of the hot lesions in the cylindrical phantom. Based on this analysis the NPW-SNR was used to quantify the relative improvements in image quality due to changes of the variable detector parameters. The image quality of a whole-body PET scanner can be improved significantly by reducing the transverse pixel size from 4 to 2.6 mm and improving the TOF resolution from 600 to 400 ps and further from 400 to 200 ps. Compared to pixel size, the TOF resolution has the larger potential to increase image quality for the simulated phantom. The introduction of two layer DOI-correction only leads to a modest improvement for the spheres at radial

Investigation of depth-of-interaction (DOI) effects in single- and dual-layer block detectors by the use of light sharing in scintillators.

PubMed

Yamamoto, Seiichi

2012-01-01

In block detectors for PET scanners that use different lengths of slits in scintillators to share light among photomultiplier tubes (PMTs), a position histogram is distorted when the depth of interaction (DOI) of the gamma photons is near the PMTs (DOI effect). However, it remains unclear whether a DOI effect is observed for block detectors that use light sharing in scintillators. To investigate the effect, I tested the effect for single- and dual-layer block detectors. In the single-layer block detector, Ce doped Gd₂SiO₅ (GSO) crystals of 1.9 × 1.9 × 15 mm³ (0.5 mol% Ce) were used. In the dual-layer block detector, GSO crystals of a 1.9 × 1.9 × 6 mm³ (1.5 mol% Ce) were used for the front layer and GSO crystals of 1.9 × 1.9 × 9 mm³ (0.5 mol% Ce) for the back layer. These scintillators were arranged to form an 8 × 8 matrix with multi-layer optical film inserted partly between the scintillators for obtaining an optimized position response with use of two dual-PMTs. Position histograms and energy responses were measured for these block detectors at three different DOI positions, and the flood histograms were obtained. The results indicated that DOI effects are observed in both block detectors, but the dual-layer block showed more severe distortion in the position histogram as well as larger energy variations. We conclude that, in the block detectors that use light sharing in the scintillators, the DOI effect is an important factor for the performance of the detectors, especially for DOI block detectors.

Bindings in working memory: The role of object-based attention.

PubMed

Gao, Zaifeng; Wu, Fan; Qiu, Fangfang; He, Kaifeng; Yang, Yue; Shen, Mowei

2017-02-01

Over the past decade, it has been debated whether retaining bindings in working memory (WM) requires more attention than retaining constituent features, focusing on domain-general attention and space-based attention. Recently, we proposed that retaining bindings in WM needs more object-based attention than retaining constituent features (Shen, Huang, & Gao, 2015, Journal of Experimental Psychology: Human Perception and Performance, doi: 10.1037/xhp0000018 ). However, only unitized visual bindings were examined; to establish the role of object-based attention in retaining bindings in WM, more emperical evidence is required. We tested 4 new bindings that had been suggested requiring no more attention than the constituent features in the WM maintenance phase: The two constituent features of binding were stored in different WM modules (cross-module binding, Experiment 1), from auditory and visual modalities (cross-modal binding, Experiment 2), or temporally (cross-time binding, Experiments 3) or spatially (cross-space binding, Experiments 4-6) separated. In the critical condition, we added a secondary object feature-report task during the delay interval of the change-detection task, such that the secondary task competed for object-based attention with the to-be-memorized stimuli. If more object-based attention is required for retaining bindings than for retaining constituent features, the secondary task should impair the binding performance to a larger degree relative to the performance of constituent features. Indeed, Experiments 1-6 consistently revealed a significantly larger impairment for bindings than for the constituent features, suggesting that object-based attention plays a pivotal role in retaining bindings in WM.

How do you assign persistent identifiers to extracts from large, complex, dynamic data sets that underpin scholarly publications?

NASA Astrophysics Data System (ADS)

Wyborn, Lesley; Car, Nicholas; Evans, Benjamin; Klump, Jens

2016-04-01

Persistent identifiers in the form of a Digital Object Identifier (DOI) are becoming more mainstream, assigned at both the collection and dataset level. For static datasets, this is a relatively straight-forward matter. However, many new data collections are dynamic, with new data being appended, models and derivative products being revised with new data, or the data itself revised as processing methods are improved. Further, because data collections are becoming accessible as services, researchers can log in and dynamically create user-defined subsets for specific research projects: they also can easily mix and match data from multiple collections, each of which can have a complex history. Inevitably extracts from such dynamic data sets underpin scholarly publications, and this presents new challenges. The National Computational Infrastructure (NCI) has been experiencing and making progress towards addressing these issues. The NCI is large node of the Research Data Services initiative (RDS) of the Australian Government's research infrastructure, which currently makes available over 10 PBytes of priority research collections, ranging from geosciences, geophysics, environment, and climate, through to astronomy, bioinformatics, and social sciences. Data are replicated to, or are produced at, NCI and then processed there to higher-level data products or directly analysed. Individual datasets range from multi-petabyte computational models and large volume raster arrays, down to gigabyte size, ultra-high resolution datasets. To facilitate access, maximise reuse and enable integration across the disciplines, datasets have been organized on a platform called the National Environmental Research Data Interoperability Platform (NERDIP). Combined, the NERDIP data collections form a rich and diverse asset for researchers: their co-location and standardization optimises the value of existing data, and forms a new resource to underpin data-intensive Science. New publication

Estimation of position resolution for DOI-PET detector using diameter 0.2 mm WLS fibers

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kaneko, Naomi; Ito, Hiroshi; Kawai, Hideyuki

We have been developing sub mm resolution andmore » $$ 1 million DOI-PET detector using wavelength shifting fibers (WLSF), scintillation crystals of plate shape and SiPM (MPPC: HAMAMATSU K. K.). Conventional design of DOI-PET detector is obtained about mm{sup 3} of resolution by using some blocks detecting gamma-ray in mm 3 voxel. It requires the production cost of $$ a few ten million or more for high technique of processing crystal and a lot of number of photo-devices, and this technology is reaching the limit of the resolution. Both higher resolution and lower cost of DOI-PET detector production is challenging for PET diagnosis population. We propose two type of detector. One is a whole body PET system, and the other for brain or small animal. Both PET system consist 6 blocks. the former consist of 6 layers 300 mm x 300 mm x 4 mm crystal plate. The latter consist 16 crystal layers, 4 x 4 crystal array. The size of crystal plate is 40 mm x 40 mm x 1 mm.The WLSF sheets connect to upper and lower plane. The whole PET systems connect 8 SiPMs are bonded on each side. For the brain PET, 9 WLSF fibers are bond on the each side. The expected position resolution maybe less than 1 mm at the former. We have estimation experimental performance the system using {sup 22}Na radioactive source. The collection efficiency of WLSF (R-3) sheet was achieved 10% with GAGG at 511 keV. The relation between reconstruction position and incident position is obtained linearity and achieved the resolution of 0.7 mm FWHM for x-axis of DOI by readout WLSF. (authors)« less

Basic performance evaluation of a Si-PM array-based LGSO phoswich DOI block detector for a high-resolution small animal PET system.

PubMed

Yamamoto, Seiichi

2013-07-01

The silicon photomultiplier (Si-PM) is a promising photodetector for PET. However, it remains unclear whether Si-PM can be used for a depth-of-interaction (DOI) detector based on the decay time differences of the scintillator where pulse shape analysis is used. For clarification, we tested the Hamamatsu 4 × 4 Si-PM array (S11065-025P) combined with scintillators that used different decay times to develop DOI block detectors using the pulse shape analysis. First, Ce-doped Gd(2)SiO(5) (GSO) scintillators of 0.5 mol% Ce were arranged in a 4 × 4 matrix and were optically coupled to the center of each pixel of the Si-PM array for measurement of the energy resolution as well as its gain variations according to the temperature. Then two types of Ce-doped Lu(1.9)Gd(0.1)Si0(5) (LGSO) scintillators, 0.025 mol% Ce (decay time: ~31 ns) and 0.75 mol% Ce (decay time: ~46 ns), were optically coupled in the DOI direction, arranged in a 11 × 7 matrix, and optically coupled to a Si-PM array for testing of the possibility of a high-resolution DOI detector. The energy resolution of the Si-PM array-based GSO block detector was 18 ± 4.4 % FWHM for a Cs-137 gamma source (662 keV). Less than 1 mm crystals were clearly resolved in the position map of the LGSO DOI block detector. The peak-to-valley ratio (P/V) derived from the pulse shape spectra of the LGSO DOI block detector was 2.2. These results confirmed that Si-PM array-based DOI block detectors are promising for high-resolution small animal PET systems.

Research on Objectives for High-School Biology

ERIC Educational Resources Information Center

Korgan, John J., Jr.; Wilson, John T.

1973-01-01

Describes procedures to develop instructional objectives for high school biology. Two kinds of objectives are identified as pre-objectives and performance objectives. Models to classify these in branches of biology and to ensure quality control are provided. (PS)

Selective amputation of the pharynx identifies a FoxA-dependent regeneration program in planaria

PubMed Central

Adler, Carolyn E; Seidel, Chris W; McKinney, Sean A; Sánchez Alvarado, Alejandro

2014-01-01

Planarian flatworms regenerate every organ after amputation. Adult pluripotent stem cells drive this ability, but how injury activates and directs stem cells into the appropriate lineages is unclear. Here we describe a single-organ regeneration assay in which ejection of the planarian pharynx is selectively induced by brief exposure of animals to sodium azide. To identify genes required for pharynx regeneration, we performed an RNAi screen of 356 genes upregulated after amputation, using successful feeding as a proxy for regeneration. We found that knockdown of 20 genes caused a wide range of regeneration phenotypes and that RNAi of the forkhead transcription factor FoxA, which is expressed in a subpopulation of stem cells, specifically inhibited regrowth of the pharynx. Selective amputation of the pharynx therefore permits the identification of genes required for organ-specific regeneration and suggests an ancient function for FoxA-dependent transcriptional programs in driving regeneration. DOI: http://dx.doi.org/10.7554/eLife.02238.001 PMID:24737865

Using raster and vector data to identify objects for classify in flood risk. A case study: Raciborz

NASA Astrophysics Data System (ADS)

Porczek, Mariusz; Rucińska, Dorota; Lewiński, Stanisław

2018-01-01

The severe flood of 1997, which seriously affected Polish, Czech and German territories, gave impetus to research into the management of flood-prone areas. The material losses caused by the "Flood of the Millennium" totalled billions of Polish zloty. The extent of the disaster and of infrastructure repair costs changed the attitude of many branches of the economy, and of science. This is the direct result of consideration of the introduction of changes into spatial management and crisis management. At the same time, it focused the interest of many who were trained in analysing the vulnerability of land-use features to natural disasters such as floods. Research into the spatial distribution of geographic environmental features susceptible to flood in the Odra valley was conducted at the Faculty of Geography and Regional Studies of the University of Warsaw using Geographic Information Systems (GIS). This study seeks to examine the possibility of adapting vector and raster data and using them for land-use classification in the context of risk of flood and inundation damage. The analysed area of the city and surrounding area of Raciborz, on the upper Odra River, is a case study for identifying objects and lands susceptible to natural hazards based on publicly available satellite databases of the highest resolution, which is a very important factor in the quality of further risk analyses for applied use. The objective of the research was to create a 10×10-m-pixel raster network using raster data made available by ESA (Copernicus Land Monitoring Service) and vector data from Open Street Map.

Active faults newly identified in Pacific Northwest

NASA Astrophysics Data System (ADS)

Balcerak, Ernie

2012-05-01

The Bellingham Basin, which lies north of Seattle and south of Vancouver around the border between the United States and Canada in the northern part of the Cascadia subduction zone, is important for understanding the regional tectonic setting and current high rates of crustal deformation in the Pacific Northwest. Using a variety of new data, Kelsey et al. identified several active faults in the Bellingham Basin that had not been previously known. These faults lie more than 60 kilometers farther north of the previously recognized northern limit of active faulting in the area. The authors note that the newly recognized faults could produce earthquakes with magnitudes between 6 and 6.5 and thus should be considered in hazard assessments for the region. (Journal of Geophysical Reserch-Solid Earth, doi:10.1029/2011JB008816, 2012)

Efficient system modeling for a small animal PET scanner with tapered DOI detectors.

PubMed

Zhang, Mengxi; Zhou, Jian; Yang, Yongfeng; Rodríguez-Villafuerte, Mercedes; Qi, Jinyi

2016-01-21

A prototype small animal positron emission tomography (PET) scanner for mouse brain imaging has been developed at UC Davis. The new scanner uses tapered detector arrays with depth of interaction (DOI) measurement. In this paper, we present an efficient system model for the tapered PET scanner using matrix factorization and a virtual scanner geometry. The factored system matrix mainly consists of two components: a sinogram blurring matrix and a geometrical matrix. The geometric matrix is based on a virtual scanner geometry. The sinogram blurring matrix is estimated by matrix factorization. We investigate the performance of different virtual scanner geometries. Both simulation study and real data experiments are performed in the fully 3D mode to study the image quality under different system models. The results indicate that the proposed matrix factorization can maintain image quality while substantially reduce the image reconstruction time and system matrix storage cost. The proposed method can be also applied to other PET scanners with DOI measurement.

Object memory effects on figure assignment: conscious object recognition is not necessary or sufficient.

PubMed

Peterson, M A; de Gelder, B; Rapcsak, S Z; Gerhardstein, P C; Bachoud-Lévi, A

2000-01-01

In three experiments we investigated whether conscious object recognition is necessary or sufficient for effects of object memories on figure assignment. In experiment 1, we examined a brain-damaged participant, AD, whose conscious object recognition is severely impaired. AD's responses about figure assignment do reveal effects from memories of object structure, indicating that conscious object recognition is not necessary for these effects, and identifying the figure-ground test employed here as a new implicit test of access to memories of object structure. In experiments 2 and 3, we tested a second brain-damaged participant, WG, for whom conscious object recognition was relatively spared. Nevertheless, effects from memories of object structure on figure assignment were not evident in WG's responses about figure assignment in experiment 2, indicating that conscious object recognition is not sufficient for effects of object memories on figure assignment. WG's performance sheds light on AD's performance, and has implications for the theoretical understanding of object memory effects on figure assignment.

25 CFR 1000.55 - Can a Tribe/Consortium appeal within DOI the Director's decision not to award a grant under this...

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Can a Tribe/Consortium appeal within DOI the Director's decision not to award a grant under this subpart? 1000.55 Section 1000.55 Indians OFFICE OF THE ASSISTANT... Negotiation Grants Advance Planning Grant Funding § 1000.55 Can a Tribe/Consortium appeal within DOI the...

25 CFR 1000.55 - Can a Tribe/Consortium appeal within DOI the Director's decision not to award a grant under this...

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Can a Tribe/Consortium appeal within DOI the Director's decision not to award a grant under this subpart? 1000.55 Section 1000.55 Indians OFFICE OF THE ASSISTANT... Negotiation Grants Advance Planning Grant Funding § 1000.55 Can a Tribe/Consortium appeal within DOI the...

Systems and Methods for Imaging of Falling Objects

NASA Technical Reports Server (NTRS)

Fallgatter, Cale (Inventor); Garrett, Tim (Inventor)

2014-01-01

Imaging of falling objects is described. Multiple images of a falling object can be captured substantially simultaneously using multiple cameras located at multiple angles around the falling object. An epipolar geometry of the captured images can be determined. The images can be rectified to parallelize epipolar lines of the epipolar geometry. Correspondence points between the images can be identified. At least a portion of the falling object can be digitally reconstructed using the identified correspondence points to create a digital reconstruction.

A procedural, pragmatist account of ethical objectivity.

PubMed

Roth, Amanda

2013-06-01

This article offers a procedural, pragmatist account of objectivity in the domain of the good that is inspired by pragmatic and feminist critiques of objectivity in philosophy of science and epistemology. I begin by asking first what we want to capture--or ought to want to capture--with a notion of ethical objectivity and in answer to this question I identify four "points" to ethical objectivity: undergirding the possibility of mistakenness, making genuine disagreement possible, making sense of our appreciation of the ethical perspectives of others, and making possible a sense of ethical improvement or learning. I then lay out a process-based account of objectivity in ethics that makes good on the four points I have identified. Finally, I consider worries related to convergence, bias, and ontology and defend the procedural, pragmatist account in light of those potential objections.

An Achievement Degree Analysis Approach to Identifying Learning Problems in Object-Oriented Programming

ERIC Educational Resources Information Center

Allinjawi, Arwa A.; Al-Nuaim, Hana A.; Krause, Paul

2014-01-01

Students often face difficulties while learning object-oriented programming (OOP) concepts. Many papers have presented various assessment methods for diagnosing learning problems to improve the teaching of programming in computer science (CS) higher education. The research presented in this article illustrates that although max-min composition is…

Method for Statically Checking an Object-oriented Computer Program Module

NASA Technical Reports Server (NTRS)

Bierhoff, Kevin M. (Inventor); Aldrich, Jonathan (Inventor)

2012-01-01

A method for statically checking an object-oriented computer program module includes the step of identifying objects within a computer program module, at least one of the objects having a plurality of references thereto, possibly from multiple clients. A discipline of permissions is imposed on the objects identified within the computer program module. The permissions enable tracking, from among a discrete set of changeable states, a subset of states each object might be in. A determination is made regarding whether the imposed permissions are violated by a potential reference to any of the identified objects. The results of the determination are output to a user.

Serotonergic and dopaminergic distinctions in the behavioral pharmacology of (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD).

PubMed

Schindler, Emmanuelle A D; Dave, Kuldip D; Smolock, Elaine M; Aloyo, Vincent J; Harvey, John A

2012-03-01

After decades of social stigma, hallucinogens have reappeared in the clinical literature demonstrating unique benefits in medicine. The precise behavioral pharmacology of these compounds remains unclear, however. Two commonly studied hallucinogens, (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD), were investigated both in vivo and in vitro to determine the pharmacology of their behavioral effects in an animal model. Rabbits were administered DOI or LSD and observed for head bob behavior after chronic drug treatment or after pretreatment with antagonist ligands. The receptor binding characteristics of DOI and LSD were studied in vitro in frontocortical homogenates from naïve rabbits or ex vivo in animals receiving an acute drug injection. Both DOI- and LSD-elicited head bobs required serotonin(2A) (5-HT(2A)) and dopamine(1) (D(1)) receptor activation. Serotonin(2B/2C) receptors were not implicated in these behaviors. In vitro studies demonstrated that LSD and the 5-HT(2A/2C) receptor antagonist, ritanserin, bound frontocortical 5-HT(2A) receptors in a pseudo-irreversible manner. In contrast, DOI and the 5-HT(2A/2C) receptor antagonist, ketanserin, bound reversibly. These binding properties were reflected in ex vivo binding studies. The two hallucinogens also differed in that LSD showed modest D(1) receptor binding affinity whereas DOI had negligible binding affinity at this receptor. Although DOI and LSD differed in their receptor binding properties, activation of 5-HT(2A) and D(1) receptors was a common mechanism for eliciting head bob behavior. These findings implicate these two receptors in the mechanism of action of hallucinogens. Copyright © 2011 Elsevier Inc. All rights reserved.

Gorie and Doi look over crew procedures on aft FD of Space Shuttle Endeavour

NASA Image and Video Library

2008-03-13

S123-E-006512 (13 March 2008) --- NASA astronaut Dominic Gorie (right), STS-123 commander, and Japan Aerospace Exploration Agency (JAXA) astronaut Takao Doi, mission specialist, look over checklists on the flight deck of Space Shuttle Endeavour while docked with the International Space Station.

Acoustically-Evoked Auditory Change Complex in Children with Auditory Neuropathy Spectrum Disorder: A Potential Objective Tool for Identifying Cochlear Implant Candidates

PubMed Central

He, Shuman; Grose, John H.; Teagle, Holly F.B.; Woodard, Jennifer; Park, Lisa R.; Hatch, Debora R.; Roush, Patricia; Buchman, Craig A.

2014-01-01

Objective: The overall aim of the study was to evaluate the feasibility of using electrophysiological measures of the auditory change complex (ACC) to identify candidates for cochlear implantation in children with auditory neuropathy spectrum disorder (ANSD). In order to achieve this overall aim, this study 1) assessed the feasibility of measuring the ACC evoked by temporal gaps in a group of children with ANSD across a wide age range; and 2) investigated the association between gap detection thresholds (GDTs) measured by the ACC recordings and open-set speech-perception performance in these subjects. Design: Nineteen children with bilateral ANSD ranging in age between 1.9 to 14.9 yrs (mean: 7.8 yrs) participated in this study. Electrophysiological recordings of the auditory event-related potential (ERP), including the onset ERP response and the ACC, were completed in all subjects and open-set speech perception was evaluated for a subgroup of sixteen subjects. For the ERP recordings, the stimulus was a Gaussian noise presented through ER-3A insert earphones to the test ear. Two stimulation conditions were used. In the “control condition,” the stimulus was an 800-ms Gaussian noise. In the “gapped condition”, the stimuli were two noise segments, each being 400 ms in duration, separated by one of five gaps (i.e. 5, 10, 20, 50, or 100 ms). The inter-stimulation interval was 1200 ms. The aided open-set speech perception ability was assessed using the Phonetically Balanced Kindergarten (PBK) word lists presented at 60 dB SPL using recorded testing material in a sound booth. For speech perception tests, subjects wore their hearing aids at the settings recommended by their clinical audiologists. For a subgroup of five subjects, psychophysical gap detection thresholds for the Gaussian noise were also assessed using a three-interval, three-alternative forced-choice procedure. Results: Responses evoked by the onset of the Gaussian noise (i.e. onset responses) were

Bottlenose dolphins perceive object features through echolocation.

PubMed

Harley, Heidi E; Putman, Erika A; Roitblat, Herbert L

2003-08-07

How organisms (including people) recognize distant objects is a fundamental question. The correspondence between object characteristics (distal stimuli), like visual shape, and sensory characteristics (proximal stimuli), like retinal projection, is ambiguous. The view that sensory systems are 'designed' to 'pick up' ecologically useful information is vague about how such mechanisms might work. In echolocating dolphins, which are studied as models for object recognition sonar systems, the correspondence between echo characteristics and object characteristics is less clear. Many cognitive scientists assume that object characteristics are extracted from proximal stimuli, but evidence for this remains ambiguous. For example, a dolphin may store 'sound templates' in its brain and identify whole objects by listening for a particular sound. Alternatively, a dolphin's brain may contain algorithms, derived through natural endowments or experience or both, which allow it to identify object characteristics based on sounds. The standard method used to address this question in many species is indirect and has led to equivocal results with dolphins. Here we outline an appropriate method and test it to show that dolphins extract object characteristics directly from echoes.

STS-87 Mission Specialists Scott and Doi with EVA coordinator Laws participate in the CEIT for their

NASA Technical Reports Server (NTRS)

1997-01-01

Participating in the Crew Equipment Integration Test (CEIT) at Kennedy Space Center are STS-87 crew members, assisted by Glenda Laws, extravehicular activity (EVA) coordinator, Johnson Space Center, at left. Next to Laws is Mission Specialist Takao Doi, Ph.D., of the National Space Development Agency of Japan, who is looking on as Mission Specialist Winston Scott gets a hands-on look at some of the equipment. The STS-87 mission will be the fourth United States Microgravity Payload and flight of the Spartan-201 deployable satellite. During the mission, scheduled for a Nov. 19 liftoff from KSC, Dr. Doi and Scott will both perform spacewalks.

Impulsive behaviour in rats induced by intracortical DOI infusions is antagonized by co-administration of an mGlu2/3 receptor agonist.

PubMed

Wischhof, Lena; Hollensteiner, Karl J; Koch, Michael

2011-12-01

The orbitofrontal cortex (OFC) and the medial prefrontal cortex (mPFC) modulate impulsive behaviours. Serotonin [5-hydroxytryptamine (5-HT)] 2A receptors have also been implicated in impulsivity and govern antagonistic interactions with metabotropic glutamate (mGlu)2/3 receptors. This study examined the interactions between 5-HT2A and mGlu2/3 receptors in the OFC and mPFC with relevance to impulsive choice and impulsive action. Impulsive choice was assessed in Lister Hooded rats, trained in a delay-discounting T-maze task, after bilateral intra-OFC infusions of the 5-HT2A/C receptor agonist DOI [(+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropan hydrochloride; 5 μg/0.5 μl] and the mGlu2/3 receptor agonist LY379268 (1 μg/0.5 μl). Impulsive action was assessed in a second group of rats trained in a five-choice serial reaction time task (5-CSRTT) and receiving bilateral intra-mPFC infusions of DOI (5 μg/0.5 μl) and LY379268 (1 μg/0.5 μl). Intra-OFC DOI increased impulsive choice, which was not seen when DOI was co-administered with LY379268. LY379268 itself had no effect on choice behaviour. Intra-mPFC DOI caused impulsive over-responding in the 5-CSRTT that was attenuated when DOI and LY379268 were co-injected. Local mPFC-infusions of LY379268 had no effect on 5-CSRTT performance. This study suggests a differential involvement of OFC and mPFC 5-HT2A receptors in impulsive choice and impulsive action. Moreover, compounds acting at mGlu2/3 receptors might have the potential to improve impulsivity-related impairments.

The Transformation of Higher Education in Vietnam after DoiMoi: A Story of "Dualism"

ERIC Educational Resources Information Center

Tran, Hien

2009-01-01

This research was undertaken to investigate the transformation of higher education reform in Vietnam since "DoiMoi," which involves examining its rationale and practical implementation. The reform reveals an interesting picture of Vietnam's higher education system, in which two development visions--a "market-led" vision and a…

The Accuracy of the VISA-P Questionnaire, Single-Leg Decline Squat, and Tendon Pain History to Identify Patellar Tendon Abnormalities in Adult Athletes.

PubMed

Mendonça, Luciana de Michelis; Ocarino, Juliana Melo; Bittencourt, Natália Franco Netto; Fernandes, Ludmila Maria Oliveira; Verhagen, Evert; Fonseca, Sérgio Teixeira

2016-08-01

Study Design Cross-sectional clinical assessment. Background Patellar tendinopathy is not always accompanied by patellar tendon abnormalities (PTAs). Thus, clinical screening tools to help identify patients with patellar tendon pain who have PTAs could enhance clinical decision making and patient prognosis. Objectives To test the diagnostic accuracy of the Victorian Institute of Sport Assessment-Patella (VISA-P) questionnaire, a single-leg decline squat (SLDS), tendon pain history, age, and years of sports participation to identify athletes with symptomatic patellar tendons who have PTAs confirmed on imaging. Methods Data provided by ultrasound examination, the VISA-P questionnaire, the SLDS, tendon pain history, age, and years of sport participation were collected in 43 athletes. A classification and regression tree (CART) model was developed to verify variables associated with PTA occurrence. Likelihood ratios (LRs) were computed for positive and negative tests. Results The SLDS, VISA-P questionnaire, and tendon pain history were associated with PTA occurrence. Athletes with negative results on all 3 tests (CART model) had a lower likelihood of having PTAs (negative LR = 0.3; 95% confidence interval [CI]: 0.2, 0.5). The isolated use of the SLDS or tendon pain history (positive LR = 4.2; 95% CI: 2.3, 7.14 and 4.5; 95% CI: 1.8, 11.1, respectively) had similar influence on probability of PTA presence compared to the CART model (positive LR = 4.1; 95% CI: 2.5, 6.3). Conclusion Although the objective was to investigate a clinical test to identify PTAs, the combined use of the tests had greater accuracy to identify individuals without PTAs. Level of Evidence Diagnosis, level 3b. J Orthop Sports Phys Ther 2016;46(8):673-680. Epub 3 Jul 2016. doi:10.2519/jospt.2016.6192.

Investigation of metabolic objectives in cultured hepatocytes.

PubMed

Uygun, Korkut; Matthew, Howard W T; Huang, Yinlun

2007-06-15

Using optimization based methods to predict fluxes in metabolic flux balance models has been a successful approach for some microorganisms, enabling construction of in silico models and even inference of some regulatory motifs. However, this success has not been translated to mammalian cells. The lack of knowledge about metabolic objectives in mammalian cells is a major obstacle that prevents utilization of various metabolic engineering tools and methods for tissue engineering and biomedical purposes. In this work, we investigate and identify possible metabolic objectives for hepatocytes cultured in vitro. To achieve this goal, we present a special data-mining procedure for identifying metabolic objective functions in mammalian cells. This multi-level optimization based algorithm enables identifying the major fluxes in the metabolic objective from MFA data in the absence of information about critical active constraints of the system. Further, once the objective is determined, active flux constraints can also be identified and analyzed. This information can be potentially used in a predictive manner to improve cell culture results or clinical metabolic outcomes. As a result of the application of this method, it was found that in vitro cultured hepatocytes maximize oxygen uptake, coupling of urea and TCA cycles, and synthesis of serine and urea. Selection of these fluxes as the metabolic objective enables accurate prediction of the flux distribution in the system given a limited amount of flux data; thus presenting a workable in silico model for cultured hepatocytes. It is observed that an overall homeostasis picture is also emergent in the findings.

Hamiltonian dynamics of extended objects

NASA Astrophysics Data System (ADS)

Capovilla, R.; Guven, J.; Rojas, E.

2004-12-01

We consider relativistic extended objects described by a reparametrization-invariant local action that depends on the extrinsic curvature of the worldvolume swept out by the object as it evolves. We provide a Hamiltonian formulation of the dynamics of such higher derivative models which is motivated by the ADM formulation of general relativity. The canonical momenta are identified by looking at boundary behaviour under small deformations of the action; the relationship between the momentum conjugate to the embedding functions and the conserved momentum density is established. The canonical Hamiltonian is constructed explicitly; the constraints on the phase space, both primary and secondary, are identified and the role they play in the theory is described. The multipliers implementing the primary constraints are identified in terms of the ADM lapse and shift variables and Hamilton's equations are shown to be consistent with the Euler Lagrange equations.

Parallel Processing of Objects in a Naming Task

ERIC Educational Resources Information Center

Meyer, Antje S.; Ouellet, Marc; Hacker, Christine

2008-01-01

The authors investigated whether speakers who named several objects processed them sequentially or in parallel. Speakers named object triplets, arranged in a triangle, in the order left, right, and bottom object. The left object was easy or difficult to identify and name. During the saccade from the left to the right object, the right object shown…

Locating an imaging radar in Canada for identifying spaceborne objects

NASA Astrophysics Data System (ADS)

Schick, William G.

1992-12-01

This research presents a study of the maximal coverage p-median facility location problem as applied to the location of an imaging radar in Canada for imaging spaceborne objects. The classical mathematical formulation of the maximal coverage p-median problem is converted into network-flow with side constraint formulations that are developed using a scaled down version of the imaging radar location problem. Two types of network-flow with side constraint formulations are developed: a network using side constraints that simulates the gains in a generalized network; and a network resembling a multi-commodity flow problem that uses side constraints to force flow along identical arcs. These small formulations are expanded to encompass a case study using 12 candidate radar sites, and 48 satellites divided into three states. SAS/OR PROC NETFLOW was used to solve the network-flow with side constraint formulations. The case study show that potential for both formulations, although the simulated gains formulation encountered singular matrix computational difficulties as a result of the very organized nature of its side constraint matrix. The multi-commodity flow formulation, when combined with equi-distribution of flow constraints, provided solutions for various values of p, the number of facilities to be selected.

Identification of simple objects in image sequences

NASA Astrophysics Data System (ADS)

Geiselmann, Christoph; Hahn, Michael

1994-08-01

We present an investigation in the identification and location of simple objects in color image sequences. As an example the identification of traffic signs is discussed. Three aspects are of special interest. First regions have to be detected which may contain the object. The separation of those regions from the background can be based on color, motion, and contours. In the experiments all three possibilities are investigated. The second aspect focuses on the extraction of suitable features for the identification of the objects. For that purpose the border line of the region of interest is used. For planar objects a sufficient approximation of perspective projection is affine mapping. In consequence, it is near at hand to extract affine-invariant features from the border line. The investigation includes invariant features based on Fourier descriptors and moments. Finally, the object is identified by maximum likelihood classification. In the experiments all three basic object types are correctly identified. The probabilities for misclassification have been found to be below 1%

From Phenomena to Objects: Segmentation of Fuzzy Objects and its Application to Oceanic Eddies

NASA Astrophysics Data System (ADS)

Wu, Qingling

A challenging image analysis problem that has received limited attention to date is the isolation of fuzzy objects---i.e. those with inherently indeterminate boundaries---from continuous field data. This dissertation seeks to bridge the gap between, on the one hand, the recognized need for Object-Based Image Analysis of fuzzy remotely sensed features, and on the other, the optimization of existing image segmentation techniques for the extraction of more discretely bounded features. Using mesoscale oceanic eddies as a case study of a fuzzy object class evident in Sea Surface Height Anomaly (SSHA) imagery, the dissertation demonstrates firstly, that the widely used region-growing and watershed segmentation techniques can be optimized and made comparable in the absence of ground truth data using the principle of parsimony. However, they both have significant shortcomings, with the region growing procedure creating contour polygons that do not follow the shape of eddies while the watershed technique frequently subdivides eddies or groups together separate eddy objects. Secondly, it was determined that these problems can be remedied by using a novel Non-Euclidian Voronoi (NEV) tessellation technique. NEV is effective in isolating the extrema associated with eddies in SSHA data while using a non-Euclidian cost-distance based procedure (based on cumulative gradients in ocean height) to define the boundaries between fuzzy objects. Using this procedure as the first stage in isolating candidate eddy objects, a novel "region-shrinking" multicriteria eddy identification algorithm was developed that includes consideration of shape and vorticity. Eddies identified by this region-shrinking technique compare favorably with those identified by existing techniques, while simplifying and improving existing automated eddy detection algorithms. However, it also tends to find a larger number of eddies as a result of its ability to separate what other techniques identify as connected

What's the object of object working memory in infancy? Unraveling 'what' and 'how many'.

PubMed

Kibbe, Melissa M; Leslie, Alan M

2013-06-01

Infants have a bandwidth-limited object working memory (WM) that can both individuate and identify objects in a scene, (answering 'how many?' or 'what?', respectively). Studies of infants' WM for objects have typically looked for limits on either 'how many' or 'what', yielding different estimates of infant capacity. Infants can keep track of about three individuals (regardless of identity), but appear to be much more limited in the number of specific identities they can recall. Why are the limits on 'how many' and 'what' different? Are the limits entirely separate, do they interact, or are they simply two different aspects of the same underlying limit? We sought to unravel these limits in a series of experiments which tested 9- and 12-month-olds' WM for object identities under varying degrees of difficulty. In a violation-of-expectation looking-time task, we hid objects one at a time behind separate screens, and then probed infants' WM for the shape identity of the penultimate object in the sequence. We manipulated the difficulty of the task by varying both the number of objects in hiding locations and the number of means by which infants could detect a shape change to the probed object. We found that 9-month-olds' WM for identities was limited by the number of hiding locations: when the probed object was one of two objects hidden (one in each of two locations), 9-month-olds succeeded, and they did so even though they were given only one means to detect the change. However, when the probed object was one of three objects hidden (one in each of three locations), they failed, even when they were given two means to detect the shape change. Twelve-month-olds, by contrast, succeeded at the most difficult task level. Results show that WM for 'how many' and for 'what' are not entirely separate. Individuated objects are tracked relatively cheaply. Maintaining bindings between indexed objects and identifying featural information incurs a greater attentional/memory cost

Foreman, Behnken, and Doi in the MDDK during Expedition 16 / STS-123 Joint Operations

NASA Image and Video Library

2008-03-18

S123-E-007123 (18 March 2008) --- Japan Aerospace Exploration Agency (JAXA) astronaut Takao Doi (top right), NASA astronauts Robert L. Behnken (top left) and Mike Foreman, all STS-123 mission specialists, are pictured on the middeck of Space Shuttle Endeavour while docked with the International Space Station.

bioGUID: resolving, discovering, and minting identifiers for biodiversity informatics

PubMed Central

Page, Roderic DM

2009-01-01

Background Linking together the data of interest to biodiversity researchers (including specimen records, images, taxonomic names, and DNA sequences) requires services that can mint, resolve, and discover globally unique identifiers (including, but not limited to, DOIs, HTTP URIs, and LSIDs). Results bioGUID implements a range of services, the core ones being an OpenURL resolver for bibliographic resources, and a LSID resolver. The LSID resolver supports Linked Data-friendly resolution using HTTP 303 redirects and content negotiation. Additional services include journal ISSN look-up, author name matching, and a tool to monitor the status of biodiversity data providers. Conclusion bioGUID is available at . Source code is available from . PMID:19900301

Object knowledge modulates colour appearance.

PubMed

Witzel, Christoph; Valkova, Hanna; Hansen, Thorsten; Gegenfurtner, Karl R

2011-01-01

We investigated the memory colour effect for colour diagnostic artificial objects. Since knowledge about these objects and their colours has been learned in everyday life, these stimuli allow the investigation of the influence of acquired object knowledge on colour appearance. These investigations are relevant for questions about how object and colour information in high-level vision interact as well as for research about the influence of learning and experience on perception in general. In order to identify suitable artificial objects, we developed a reaction time paradigm that measures (subjective) colour diagnosticity. In the main experiment, participants adjusted sixteen such objects to their typical colour as well as to grey. If the achromatic object appears in its typical colour, then participants should adjust it to the opponent colour in order to subjectively perceive it as grey. We found that knowledge about the typical colour influences the colour appearance of artificial objects. This effect was particularly strong along the daylight axis.

Object knowledge modulates colour appearance

PubMed Central

Witzel, Christoph; Valkova, Hanna; Hansen, Thorsten; Gegenfurtner, Karl R

2011-01-01

We investigated the memory colour effect for colour diagnostic artificial objects. Since knowledge about these objects and their colours has been learned in everyday life, these stimuli allow the investigation of the influence of acquired object knowledge on colour appearance. These investigations are relevant for questions about how object and colour information in high-level vision interact as well as for research about the influence of learning and experience on perception in general. In order to identify suitable artificial objects, we developed a reaction time paradigm that measures (subjective) colour diagnosticity. In the main experiment, participants adjusted sixteen such objects to their typical colour as well as to grey. If the achromatic object appears in its typical colour, then participants should adjust it to the opponent colour in order to subjectively perceive it as grey. We found that knowledge about the typical colour influences the colour appearance of artificial objects. This effect was particularly strong along the daylight axis. PMID:23145224

Identifying the perceptive users for online social systems

PubMed Central

Liu, Xiao-Lu; Guo, Qiang; Han, Jing-Ti

2017-01-01

In this paper, the perceptive user, who could identify the high-quality objects in their initial lifespan, is presented. By tracking the ratings given to the rewarded objects, we present a method to identify the user perceptibility, which is defined as the capability that a user can identify these objects at their early lifespan. Moreover, we investigate the behavior patterns of the perceptive users from three dimensions: User activity, correlation characteristics of user rating series and user reputation. The experimental results for the empirical networks indicate that high perceptibility users show significantly different behavior patterns with the others: Having larger degree, stronger correlation of rating series and higher reputation. Furthermore, in view of the hysteresis in finding the rewarded objects, we present a general framework for identifying the high perceptibility users based on user behavior patterns. The experimental results show that this work is helpful for deeply understanding the collective behavior patterns for online users. PMID:28704382

Identifying the perceptive users for online social systems.

PubMed

Liu, Jian-Guo; Liu, Xiao-Lu; Guo, Qiang; Han, Jing-Ti

2017-01-01

In this paper, the perceptive user, who could identify the high-quality objects in their initial lifespan, is presented. By tracking the ratings given to the rewarded objects, we present a method to identify the user perceptibility, which is defined as the capability that a user can identify these objects at their early lifespan. Moreover, we investigate the behavior patterns of the perceptive users from three dimensions: User activity, correlation characteristics of user rating series and user reputation. The experimental results for the empirical networks indicate that high perceptibility users show significantly different behavior patterns with the others: Having larger degree, stronger correlation of rating series and higher reputation. Furthermore, in view of the hysteresis in finding the rewarded objects, we present a general framework for identifying the high perceptibility users based on user behavior patterns. The experimental results show that this work is helpful for deeply understanding the collective behavior patterns for online users.

Negative decision outcomes are more common among people with lower decision-making competence: an item-level analysis of the Decision Outcome Inventory (DOI).

PubMed

Parker, Andrew M; Bruine de Bruin, Wändi; Fischhoff, Baruch

2015-01-01

Most behavioral decision research takes place in carefully controlled laboratory settings, and examination of relationships between performance and specific real-world decision outcomes is rare. One prior study shows that people who perform better on hypothetical decision tasks, assessed using the Adult Decision-Making Competence (A-DMC) measure, also tend to experience better real-world decision outcomes, as reported on the Decision Outcomes Inventory (DOI). The DOI score reflects avoidance of outcomes that could result from poor decisions, ranging from serious (e.g., bankruptcy) to minor (e.g., blisters from sunburn). The present analyses go beyond the initial work, which focused on the overall DOI score, by analyzing the relationships between specific decision outcomes and A-DMC performance. Most outcomes are significantly more likely among people with lower A-DMC scores, even after taking into account two variables expected to produce worse real-world decision outcomes: younger age and lower socio-economic status. We discuss the usefulness of DOI as a measure of successful real-world decision-making.

Multiple Object Based RFID System Using Security Level

NASA Astrophysics Data System (ADS)

Kim, Jiyeon; Jung, Jongjin; Ryu, Ukjae; Ko, Hoon; Joe, Susan; Lee, Yongjun; Kim, Boyeon; Chang, Yunseok; Lee, Kyoonha

2007-12-01

RFID systems are increasingly applied for operational convenience in wide range of industries and individual life. However, it is uneasy for a person to control many tags because common RFID systems have the restriction that a tag used to identify just a single object. In addition, RFID systems can make some serious problems in violation of privacy and security because of their radio frequency communication. In this paper, we propose a multiple object RFID tag which can keep multiple object identifiers for different applications in a same tag. The proposed tag allows simultaneous access for their pair applications. We also propose an authentication protocol for multiple object tag to prevent serious problems of security and privacy in RFID applications. Especially, we focus on efficiency of the authentication protocol by considering security levels of applications. In the proposed protocol, the applications go through different authentication procedures according to security level of the object identifier stored in the tag. We implemented the proposed RFID scheme and made experimental results about efficiency and stability for the scheme.

Feasibility of Deploying Inhaler Sensors to Identify the Impacts of Environmental Triggers and Built Environment Factors on Asthma Short-Acting Bronchodilator Use.

PubMed

Su, Jason G; Barrett, Meredith A; Henderson, Kelly; Humblet, Olivier; Smith, Ted; Sublett, James W; Nesbitt, LaQuandra; Hogg, Chris; Van Sickle, David; Sublett, James L

2017-02-01

Epidemiological asthma research has relied upon self-reported symptoms or healthcare utilization data, and used the residential address as the primary location for exposure. These data sources can be temporally limited, spatially aggregated, subjective, and burdensome for the patient to collect. First, we aimed to test the feasibility of collecting rescue inhaler use data in space-time using electronic sensors. Second, we aimed to evaluate whether these data have the potential to identify environmental triggers and built environment factors associated with rescue inhaler use and to determine whether these findings would be consistent with the existing literature. We utilized zero-truncated negative binomial models to identify triggers associated with inhaler use, and implemented three sensitivity analyses to validate our findings. Electronic sensors fitted on metered dose inhalers tracked 5,660 rescue inhaler use events in space and time for 140 participants from 13 June 2012 to 28 February 2014. We found that the inhaler sensors were feasible in passively collecting objective rescue inhaler use data. We identified several environmental triggers with a positive and significant association with inhaler use, including: AQI, PM10, weed pollen, and mold. Conversely, the spatial distribution of tree cover demonstrated a negative and significant association with inhaler use. Utilizing a sensor to capture the signal of rescue inhaler use in space-time offered a passive and objective signal of asthma activity. This approach enabled detailed analyses to identify environmental triggers and built environment factors that are associated with asthma symptoms beyond the residential address. The application of these new technologies has the potential to improve our surveillance and understanding of asthma. Citation: Su JG, Barrett MA, Henderson K, Humblet O, Smith T, Sublett JW, Nesbitt L, Hogg C, Van Sickle D, Sublett JL. 2017. Feasibility of deploying inhaler sensors to

A chemical proteomic atlas of brain serine hydrolases identifies cell type-specific pathways regulating neuroinflammation

PubMed Central

Viader, Andreu; Ogasawara, Daisuke; Joslyn, Christopher M; Sanchez-Alavez, Manuel; Mori, Simone; Nguyen, William; Conti, Bruno; Cravatt, Benjamin F

2016-01-01

Metabolic specialization among major brain cell types is central to nervous system function and determined in large part by the cellular distribution of enzymes. Serine hydrolases are a diverse enzyme class that plays fundamental roles in CNS metabolism and signaling. Here, we perform an activity-based proteomic analysis of primary mouse neurons, astrocytes, and microglia to furnish a global portrait of the cellular anatomy of serine hydrolases in the brain. We uncover compelling evidence for the cellular compartmentalization of key chemical transmission pathways, including the functional segregation of endocannabinoid (eCB) biosynthetic enzymes diacylglycerol lipase-alpha (DAGLα) and –beta (DAGLβ) to neurons and microglia, respectively. Disruption of DAGLβ perturbed eCB-eicosanoid crosstalk specifically in microglia and suppressed neuroinflammatory events in vivo independently of broader effects on eCB content. Mapping the cellular distribution of metabolic enzymes thus identifies pathways for regulating specialized inflammatory responses in the brain while avoiding global alterations in CNS function. DOI: http://dx.doi.org/10.7554/eLife.12345.001 PMID:26779719

Data Identifiers and Citations Enable Reproducible Science

NASA Astrophysics Data System (ADS)

Tilmes, C.

2011-12-01

Modern science often involves data processing with tremendous volumes of data. Keeping track of that data has been a growing challenge for data center. Researchers who access and use that data don't always reference and cite their data sources adequately for consumers of their research to follow their methodology or reproduce their analyses or experiments. Recent research has led to recommendations for good identifiers and citations that can help address this problem. This paper will describe some of the best practices in data identifiers, reference and citation. Using a simplified example scenario based on a long term remote sensing satellite mission, it will explore issues in identifying dynamic data sets and the importance of good data citations for reproducibility. It will describe the difference between granule and collection level identifiers, using UUIDs and DOIs to illustrate some recommendations for developing identifiers and assigning them during data processing. As data processors create data products, the provenance of the input products and precise steps that led to their creation are recorded and published for users of the data to see. As researchers access the data from an archive, they can use the provenance to help understand the genesis of the data, which could have effects on their usage of the data. By citing the data on publishing their research, others can retrieve the precise data used in their research and reproduce the analyses and experiments to confirm the results. Describing the experiment to a sufficient extent to reproduce the research enforces a formal approach that lends credibility to the results, and ultimately, to the policies of decision makers depending on that research.

What Does it Mean to Publish Data in Earth System Science Data Journal?

NASA Astrophysics Data System (ADS)

Carlson, D.; Pfeiffenberger, H.

2015-12-01

The availability of more than 120 data sets in ESSD represents an unprecedented effort by providers, data centers and ESSD. ESSD data sets and their accompanying data descriptions undergo rigorous review. The data sets reside at any of more than 20 cooperating data centers. The ESSD publication process depends on but challenges the concepts of digital object identification and exacerbates the varied interpretations of the phrase 'data publication'. ESSD adopts the digital object identifier (doi). Key questions apply to doi's and other identifiers. How will persistent identifiers point accurately to distributed or replicated data? How should data centers and data publishers use identifier technologies to ensure authenticity and integrity? Should metadata associated with identifiers distinguish among raw, quality controlled and derived data processing levels, or indicate license or copyright status?Data centers publish data sets according to internal metadata standards but without indicators of quality control. Publication in this sense indicates availability. National data portals compile, serve and publish data products as a service to national researchers and, often, to meet national requirements. Publication in this second case indicates availability in a national context; the data themselves may still reside at separate data centers. Data journals such as ESSD or Scientific Data publish peer-reviewed, quality controlled data sets. These data sets almost always reside at a separate data center - the journal and the center maintain explicit identifier linkages. Data journals add quality to the feature of availability. A single data set processed through these layers will generate three independent doi's but the doi's will provide little information about availability or quality. Could the data world learn from the URL world to consider additions? Suffixes? Could we use our experience with processing levels or data maturity to propose and agree such extensions?

Gamifying Video Object Segmentation.

PubMed

Spampinato, Concetto; Palazzo, Simone; Giordano, Daniela

2017-10-01

Video object segmentation can be considered as one of the most challenging computer vision problems. Indeed, so far, no existing solution is able to effectively deal with the peculiarities of real-world videos, especially in cases of articulated motion and object occlusions; limitations that appear more evident when we compare the performance of automated methods with the human one. However, manually segmenting objects in videos is largely impractical as it requires a lot of time and concentration. To address this problem, in this paper we propose an interactive video object segmentation method, which exploits, on one hand, the capability of humans to identify correctly objects in visual scenes, and on the other hand, the collective human brainpower to solve challenging and large-scale tasks. In particular, our method relies on a game with a purpose to collect human inputs on object locations, followed by an accurate segmentation phase achieved by optimizing an energy function encoding spatial and temporal constraints between object regions as well as human-provided location priors. Performance analysis carried out on complex video benchmarks, and exploiting data provided by over 60 users, demonstrated that our method shows a better trade-off between annotation times and segmentation accuracy than interactive video annotation and automated video object segmentation approaches.

On the Utility of ToxCast™ and ToxPi as Methods for Identifying New Obesogens

PubMed Central

Janesick, Amanda Shaine; Dimastrogiovanni, Giorgio; Vanek, Lenka; Boulos, Christy; Chamorro-García, Raquel; Tang, Weiyi; Blumberg, Bruce

2016-01-01

Background: In ToxCast™ Phase I, the U.S. EPA commissioned screening of 320 pesticides, herbicides, fungicides, and other chemicals in a series of high-throughput assays. The agency also developed a toxicological prioritization tool, ToxPi, to facilitate using ToxCast™ assays to predict biological function. Objectives: We asked whether top-scoring PPARγ activators identified in ToxCast™ Phase I were genuine PPARγ activators and inducers of adipogenesis. Next, we identified ToxCast™ assays that should predict adipogenesis, developed an adipogenesis ToxPi, and asked how well the ToxPi predicted adipogenic activity. Methods: We used transient transfection to test the ability of ToxCast™ chemicals to modulate PPARγ and RXRα, and differentiation assays employing 3T3-L1 preadipocytes and mouse bone marrow-derived mesenchymal stem cells (mBMSCs) to evaluate the adipogenic capacity of ToxCast™ chemicals. Results: Only 5/21 of the top scoring ToxCast™ PPARγ activators were activators in our assays, 3 were PPARγ antagonists, the remainder were inactive. The bona fide PPARγ activators we identified induced adipogenesis in 3T3-L1 cells and mBMSCs. Only 7 of the 17 chemicals predicted to be active by the ToxPi promoted adipogenesis, 1 inhibited adipogenesis, and 2 of the 7 predicted negatives were also adipogenic. Of these 9 adipogenic chemicals, 3 activated PPARγ, and 1 activated RXRα. Conclusions: ToxCast™ PPARγ and RXRα assays do not correlate well with laboratory measurements of PPARγ and RXRα activity. The adipogenesis ToxPi performed poorly, perhaps due to the performance of ToxCast™ assays. We observed a modest predictive value of ToxCast™ for PPARγ and RXRα activation and adipogenesis and it is likely that many obesogenic chemicals remain to be identified. Citation: Janesick AS, Dimastrogiovanni G, Vanek L, Boulos C, Chamorro-García R, Tang W, Blumberg B. 2016. On the utility of ToxCast™ and ToxPi as methods for identifying new

Standards-based metadata procedures for retrieving data for display or mining utilizing persistent (data-DOI) identifiers.

PubMed

Harvey, Matthew J; Mason, Nicholas J; McLean, Andrew; Rzepa, Henry S

2015-01-01

We describe three different procedures based on metadata standards for enabling automated retrieval of scientific data from digital repositories utilising the persistent identifier of the dataset with optional specification of the attributes of the data document such as filename or media type. The procedures are demonstrated using the JSmol molecular visualizer as a component of a web page and Avogadro as a stand-alone modelling program. We compare our methods for automated retrieval of data from a standards-compliant data repository with those currently in operation for a selection of existing molecular databases and repositories. Our methods illustrate the importance of adopting a standards-based approach of using metadata declarations to increase access to and discoverability of repository-based data. Graphical abstract.

Sexual Health Curricula in U.S. Medical Schools: Current Educational Objectives

ERIC Educational Resources Information Center

Galletly, Carol; Lechuga, Julia; Layde, Joseph B.; Pinkerton, Steven

2010-01-01

Objective: The authors identify the explicit and implicit objectives that shape decisions about what medical schools teach regarding human sexuality. Methods: The authors reviewed relevant articles in journals, physician licensing examinations, and publications by professional organizations to identify learning objectives for human sexuality in…

Multiscale, multispectral and multitemporal satellite data to identify archaeological remains in the archaeological area of Tiwanaku (Bolivia)

NASA Astrophysics Data System (ADS)

Masini, Nicola; Lasaponara, Rosa

2015-04-01

The aim of this paper is to investigate the cultural landscape of the archaeological area of Tiwanaku (Bolivia) using multiscale, multispectral and multitemporal satellite data. Geospatial analysis techniques were applied to the satellite data sets in order to enhance and map traces of past human activities and perform a spatial characterization of environmental and cultural patterns. In particular, in the Tiwanaku area, the approach based on local indicators of spatial autocorrelation (LISA) applied to ASTER data allowed us to identify traces of a possible ancient hydrographic network with a clear spatial relation with the well-known moat surrounding the core of the monumental area. The same approach applied to QuickBird data, allowed us to identify numerous traces of archaeological interest, in Mollo Kontu mound, less investigated than the monumental area. Some of these traces were in perfect accordance with the results of independent studies, other were completely unknown. As a whole, the detected features, composing a geometric pattern with roughly North-South orientation, closely match those of the other residential contexts at Tiwanaku. These new insights, captured from multitemporal ASTER and QuickBird data processing, suggested new questions on the ancient landscape and provided important information for planning future field surveys and archaeogeophyical investigations. Reference [1] Lasaponara R., Masini N. 2014. Beyond modern landscape features: New insights in thearchaeological area of Tiwanaku in Bolivia from satellite data. International Journal of Applied Earth Observation and Geoinformation, 26, 464-471, http://dx.doi.org/10.1016/j.jag.2013.09.00. [2] Tapete D., Cigna F., Masini N., Lasaponara R. 2013. Prospection and monitoring of the archaeological heritage of Nasca, Peru, with ENVISAT ASAR, Archaeological Prospection, 20, 133-147, doi: 10.1002/arp.1449. [3] Lasaponara R, N Masini, 2012 Satellite Remote Sensing, A New Tool for Archaeology (Series

A new forest-dwelling Bent-toed Gecko (Squamata: Gekkonidae: Cyrtodactylus) from Doi Inthanon, Chiang Mai Province, northern Thailand.

PubMed

Kunya, Kirati; Sumontha, Montri; Panitvong, Nonn; Dongkumfu, Wuttipong; Sirisamphan, Thana; Pauwels, Olivier S G

2015-01-14

We describe a new forest-dwelling Cyrtodactylus from Doi Inthanon, Chiang Mai Province, northern Thailand. Cyrtodactylus inthanon sp. nov. is characterized by a maximum known SVL of 87.3 mm; 18 to 20 longitudinal rows of dorsal tubercles; a continuous series of 34 to 37 enlarged femoro-precloacal scales, including four to six pitted (female) or pore-bearing (male) scales on each femur separated by a diastema from five pitted (females) or pore-bearing (male) precloacal scales; no precloacal groove or depression; transversely enlarged subcaudal scales; and three to five irregular beige dorsal bands between limb insertions. The discovery of a new reptile endemic to Doi Inthanon reinforces the high importance of this mountain in terms of biodiversity conservation.

Mission objectives and trajectories

NASA Technical Reports Server (NTRS)

1973-01-01

The present state of the knowledge of asteroids was assessed to identify mission and target priorities for planning asteroidal flights in the 1980's and beyond. Mission objectives, mission analysis, trajectory studies, and cost analysis are discussed. A bibliography of reports and technical memoranda is included.

First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass

PubMed Central

Wang, Guangliang; Rajpurohit, Surendra K; Delaspre, Fabien; Walker, Steven L; White, David T; Ceasrine, Alexis; Kuruvilla, Rejji; Li, Ruo-jing; Shim, Joong S; Liu, Jun O; Parsons, Michael J; Mumm, Jeff S

2015-01-01

Whole-organism chemical screening can circumvent bottlenecks that impede drug discovery. However, in vivo screens have not attained throughput capacities possible with in vitro assays. We therefore developed a method enabling in vivo high-throughput screening (HTS) in zebrafish, termed automated reporter quantification in vivo (ARQiv). In this study, ARQiv was combined with robotics to fully actualize whole-organism HTS (ARQiv-HTS). In a primary screen, this platform quantified cell-specific fluorescent reporters in >500,000 transgenic zebrafish larvae to identify FDA-approved (Federal Drug Administration) drugs that increased the number of insulin-producing β cells in the pancreas. 24 drugs were confirmed as inducers of endocrine differentiation and/or stimulators of β-cell proliferation. Further, we discovered novel roles for NF-κB signaling in regulating endocrine differentiation and for serotonergic signaling in selectively stimulating β-cell proliferation. These studies demonstrate the power of ARQiv-HTS for drug discovery and provide unique insights into signaling pathways controlling β-cell mass, potential therapeutic targets for treating diabetes. DOI: http://dx.doi.org/10.7554/eLife.08261.001 PMID:26218223

The probability of object-scene co-occurrence influences object identification processes.

PubMed

Sauvé, Geneviève; Harmand, Mariane; Vanni, Léa; Brodeur, Mathieu B

2017-07-01

Contextual information allows the human brain to make predictions about the identity of objects that might be seen and irregularities between an object and its background slow down perception and identification processes. Bar and colleagues modeled the mechanisms underlying this beneficial effect suggesting that the brain stocks information about the statistical regularities of object and scene co-occurrence. Their model suggests that these recurring regularities could be conceptualized along a continuum in which the probability of seeing an object within a given scene can be high (probable condition), moderate (improbable condition) or null (impossible condition). In the present experiment, we propose to disentangle the electrophysiological correlates of these context effects by directly comparing object-scene pairs found along this continuum. We recorded the event-related potentials of 30 healthy participants (18-34 years old) and analyzed their brain activity in three time windows associated with context effects. We observed anterior negativities between 250 and 500 ms after object onset for the improbable and impossible conditions (improbable more negative than impossible) compared to the probable condition as well as a parieto-occipital positivity (improbable more positive than impossible). The brain may use different processing pathways to identify objects depending on whether the probability of co-occurrence with the scene is moderate (rely more on top-down effects) or null (rely more on bottom-up influences). The posterior positivity could index error monitoring aimed to ensure that no false information is integrated into mental representations of the world.

Phospholipase C mediates (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-, but not lysergic acid diethylamide (LSD)-elicited head bobs in rabbit medial prefrontal cortex.

PubMed

Schindler, Emmanuelle A D; Harvey, John A; Aloyo, Vincent J

2013-01-23

The phenethylamine and indoleamine classes of hallucinogens demonstrate distinct pharmacological properties, although they share a serotonin(2A) (5-HT(2A)) receptor mechanism of action (MOA). The 5-HT(2A) receptor signals through phosphatidylinositol (PI) hydrolysis, which is initiated upon activation of phospholipase C (PLC). The role of PI hydrolysis in the effects of hallucinogens remains unclear. In order to better understand the role of PI hydrolysis in the MOA of hallucinogens, the PLC inhibitor, 1-[6-((17β-3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl]-1H-pyrrole-2,5-dione (U73122), was used to study the effects of two hallucinogens, the phenethylamine, (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), and the indoleamine, lysergic acid diethylamide (LSD). PI hydrolysis was quantified through release of [3H]inositol-4-phosphate from living rabbit frontocortical tissue prisms. Head bobs were counted after hallucinogens were infused into the medial prefrontal cortex (mPFC) of rabbits. Both DOI and LSD stimulated PI hydrolysis in frontocortical tissue through activation of PLC. DOI-stimulated PI hydrolysis was blocked by 5-HT(2A/2C) receptor antagonist, ketanserin, whereas the LSD signal was blocked by 5-HT(2B/2C) receptor antagonist, SB206553. When infused into the mPFC, both DOI- and LSD-elicited head bobs. Pretreatment with U73122 blocked DOI-, but not LSD-elicited head bobs. The two hallucinogens investigated were distinct in their activation of the PI hydrolysis signaling pathway. The serotonergic receptors involved with DOI and LSD signals in frontocortical tissue were different. Furthermore, PLC activation in mPFC was necessary for DOI-elicited head bobs, whereas LSD-elicited head bobs were independent of this pathway. These novel findings urge closer investigation into the intracellular mechanism of action of these unique compounds. Published by Elsevier B.V.

3D-Modeling of deformed halite hopper crystals: Object based image analysis and support vector machine, a first evaluation

NASA Astrophysics Data System (ADS)

Leitner, Christoph; Hofmann, Peter; Marschallinger, Robert

2014-05-01

Halite hopper crystals are thought to develop by displacive growth in unconsolidated mud (Gornitz & Schreiber, 1984). The Alpine Haselgebirge, but also e.g. the salt deposits of the Rhine graben (mined at the beginning of the 20th century), comprise hopper crystals with shapes of cuboids, parallelepipeds and rhombohedrons (Görgey, 1912). Obviously, they deformed under oriented stress, which had been tried to reconstruct with respect to the sedimentary layering (Leitner et al., 2013). In the present work, deformed halite hopper crystals embedded in mudrock were automated reconstructed. Object based image analysis (OBIA) has been used successfully in remote sensing for 2D images before. The present study represents the first time that the method was used for reconstruction of three dimensional geological objects. First, manually a reference (gold standard) was created by redrawing contours of the halite crystals on each HRXCT scanning slice. Then, for OBIA, the computer program eCognition was used. For the automated reconstruction a rule set was developed. Thereby, the strength of OBIA was to recognize all objects similar to halite hopper crystals and in particular to eliminate cracks. In a second step, all the objects unsuitable for a structural deformation analysis were dismissed using a support vector machine (SVM) (clusters, polyhalite-coated crystals and spherical halites) The SVM simultaneously drastically reduced the number of halites. From 184 OBIA-objects 67 well shaped remained, which comes close to the number of pre-selected 52 objects. To assess the accuracy of the automated reconstruction, the result before and after SVM was compared to the reference, i.e. the gold standard. State-of the art per-scene statistics were extended to a per-object statistics. Görgey R (1912) Zur Kenntnis der Kalisalzlager von Wittelsheim im Ober-Elsaß. Tschermaks Mineral Petrogr Mitt 31:339-468 Gornitz VM, Schreiber BC (1981) Displacive halite hoppers from the dead sea

Online-Based Approaches to Identify Real Journals and Publishers from Hijacked Ones.

PubMed

Asadi, Amin; Rahbar, Nader; Asadi, Meisam; Asadi, Fahime; Khalili Paji, Kokab

2017-02-01

The aim of the present paper was to introduce some online-based approaches to evaluate scientific journals and publishers and to differentiate them from the hijacked ones, regardless of their disciplines. With the advent of open-access journals, many hijacked journals and publishers have deceitfully assumed the mantle of authenticity in order to take advantage of researchers and students. Although these hijacked journals and publishers can be identified through checking their advertisement techniques and their websites, these ways do not always result in their identification. There exist certain online-based approaches, such as using Master Journal List provided by Thomson Reuters, and Scopus database, and using the DOI of a paper, to certify the realness of a journal or publisher. It is indispensable that inexperienced students and researchers know these methods so as to identify hijacked journals and publishers with a higher level of probability.

STS-87 Mission Specialist Doi addresses the media at the SLF

NASA Technical Reports Server (NTRS)

1997-01-01

As STS-87 Commander Kevin Kregel looks on, Mission Specialist Takao Doi, Ph.D., of the National Space Development Agency of Japan addresses members of the press and media at Kennedy Space Center's Shuttle Landing Facility after arriving for the final prelaunch activities leading up to the scheduled Nov. 19 liftoff. Other STS-87 crew members not pictured are Pilot Steven Lindsey; Mission Specialists Kalpana Chawla, Ph.D., and Winston Scott; and Payload Specialist Leonid Kadenyuk of the National Space Agency of Ukraine. STS-87 will be the fourth flight of the United States Microgravity Payload and the Spartan-201 deployable satellite.

Doi-Peliti path integral methods for stochastic systems with partial exclusion

NASA Astrophysics Data System (ADS)

Greenman, Chris D.

2018-09-01

Doi-Peliti methods are developed for stochastic models with finite maximum occupation numbers per site. We provide a generalized framework for the different Fock spaces reported in the literature. Paragrassmannian techniques are then utilized to construct path integral formulations of factorial moments. We show that for many models of interest, a Magnus expansion is required to construct a suitable action, meaning actions containing a finite number of terms are not always feasible. However, for such systems, perturbative techniques are still viable, and for some examples, including carrying capacity population dynamics, and diffusion with partial exclusion, the expansions are exactly summable.

The effect of colour congruency on shape discriminations of novel objects.

PubMed

Nicholson, Karen G; Humphrey, G Keith

2004-01-01

Although visual object recognition is primarily shape driven, colour assists the recognition of some objects. It is unclear, however, just how colour information is coded with respect to shape in long-term memory and how the availability of colour in the visual image facilitates object recognition. We examined the role of colour in the recognition of novel, 3-D objects by manipulating the congruency of object colour across the study and test phases, using an old/new shape-identification task. In experiment 1, we found that participants were faster at correctly identifying old objects on the basis of shape information when these objects were presented in their original colour, rather than in a different colour. In experiments 2 and 3, we found that participants were faster at correctly identifying old objects on the basis of shape information when these objects were presented with their original part-colour conjunctions, rather than in different or in reversed part-colour conjunctions. In experiment 4, we found that participants were quite poor at the verbal recall of part-colour conjunctions for correctly identified old objects, presented as grey-scale images at test. In experiment 5, we found that participants were significantly slower at correctly identifying old objects when object colour was incongruent across study and test, than when background colour was incongruent across study and test. The results of these experiments suggest that both shape and colour information are stored as part of the long-term representation of these novel objects. Results are discussed in terms of how colour might be coded with respect to shape in stored object representations.

Does object view influence the scene consistency effect?

PubMed

Sastyin, Gergo; Niimi, Ryosuke; Yokosawa, Kazuhiko

2015-04-01

Traditional research on the scene consistency effect only used clearly recognizable object stimuli to show mutually interactive context effects for both the object and background components on scene perception (Davenport & Potter in Psychological Science, 15, 559-564, 2004). However, in real environments, objects are viewed from multiple viewpoints, including an accidental, hard-to-recognize one. When the observers named target objects in scenes (Experiments 1a and 1b, object recognition task), we replicated the scene consistency effect (i.e., there was higher accuracy for the objects with consistent backgrounds). However, there was a significant interaction effect between consistency and object viewpoint, which indicated that the scene consistency effect was more important for identifying objects in the accidental view condition than in the canonical view condition. Therefore, the object recognition system may rely more on the scene context when the object is difficult to recognize. In Experiment 2, the observers identified the background (background recognition task) while the scene consistency and object views were manipulated. The results showed that object viewpoint had no effect, while the scene consistency effect was observed. More specifically, the canonical and accidental views both equally provided contextual information for scene perception. These findings suggested that the mechanism for conscious recognition of objects could be dissociated from the mechanism for visual analysis of object images that were part of a scene. The "context" that the object images provided may have been derived from its view-invariant, relatively low-level visual features (e.g., color), rather than its semantic information.

Cognitive object recognition system (CORS)

NASA Astrophysics Data System (ADS)

Raju, Chaitanya; Varadarajan, Karthik Mahesh; Krishnamurthi, Niyant; Xu, Shuli; Biederman, Irving; Kelley, Troy

2010-04-01

We have developed a framework, Cognitive Object Recognition System (CORS), inspired by current neurocomputational models and psychophysical research in which multiple recognition algorithms (shape based geometric primitives, 'geons,' and non-geometric feature-based algorithms) are integrated to provide a comprehensive solution to object recognition and landmarking. Objects are defined as a combination of geons, corresponding to their simple parts, and the relations among the parts. However, those objects that are not easily decomposable into geons, such as bushes and trees, are recognized by CORS using "feature-based" algorithms. The unique interaction between these algorithms is a novel approach that combines the effectiveness of both algorithms and takes us closer to a generalized approach to object recognition. CORS allows recognition of objects through a larger range of poses using geometric primitives and performs well under heavy occlusion - about 35% of object surface is sufficient. Furthermore, geon composition of an object allows image understanding and reasoning even with novel objects. With reliable landmarking capability, the system improves vision-based robot navigation in GPS-denied environments. Feasibility of the CORS system was demonstrated with real stereo images captured from a Pioneer robot. The system can currently identify doors, door handles, staircases, trashcans and other relevant landmarks in the indoor environment.

Wikipedia as a gateway to biomedical research: The relative distribution and use of citations in the English Wikipedia.

PubMed

Maggio, Lauren A; Willinsky, John M; Steinberg, Ryan M; Mietchen, Daniel; Wass, Joseph L; Dong, Ting

2017-01-01

Wikipedia is a gateway to knowledge. However, the extent to which this gateway ends at Wikipedia or continues via supporting citations is unknown. Wikipedia's gateway functionality has implications for information design and education, notably in medicine. This study aims to establish benchmarks for the relative distribution and referral (click) rate of citations-as indicated by presence of a Digital Object Identifier (DOI)-from Wikipedia, with a focus on medical citations. DOIs referred from the English Wikipedia in August 2016 were obtained from Crossref.org. Next, based on a DOI's presence on a WikiProject Medicine page, all DOIs in Wikipedia were categorized as medical (WP:MED) or non-medical (non-WP:MED). Using this categorization, referred DOIs were classified as WP:MED, non-WP:MED, or BOTH, meaning the DOI may have been referred from either category. Data were analyzed using descriptive and inferential statistics. Out of 5.2 million Wikipedia pages, 4.42% (n = 229,857) included at least one DOI. 68,870 were identified as WP:MED, with 22.14% (n = 15,250) featuring one or more DOIs. WP:MED pages featured on average 8.88 DOI citations per page, whereas non-WP:MED pages had on average 4.28 DOI citations. For DOIs only on WP:MED pages, a DOI was referred every 2,283 pageviews and for non-WP:MED pages every 2,467 pageviews. DOIs from BOTH pages accounted for 12% (n = 58,475). The referral of DOI citations found in BOTH could not be assigned to WP:MED or non-WP:MED, as the page from which the referral was made was not provided with the data. While these results cannot provide evidence of greater citation referral from WP:MED than non-WP:MED, they do provide benchmarks to assess strategies for changing referral patterns. These changes might include editors adopting new methods for designing and presenting citations or the introduction of teaching strategies that address the value of consulting citations as a tool for extending learning.

77 FR 19307 - Renewal of Information Collection; OMB Control Number 1040-0001, DOI Programmatic Clearance for...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-30

... Number 1040-0001, DOI Programmatic Clearance for Customer Satisfaction Surveys AGENCY: Department of the... Customer Satisfaction Surveys'' in your email subject line. Include your name and return address in your... accountability by promoting a new focus on results, service quality, and customer satisfaction.'' In order to...

Object Oriented Learning Objects

ERIC Educational Resources Information Center

Morris, Ed

2005-01-01

We apply the object oriented software engineering (OOSE) design methodology for software objects (SOs) to learning objects (LOs). OOSE extends and refines design principles for authoring dynamic reusable LOs. Our learning object class (LOC) is a template from which individualised LOs can be dynamically created for, or by, students. The properties…

Auditory memory can be object based.

PubMed

Dyson, Benjamin J; Ishfaq, Feraz

2008-04-01

Identifying how memories are organized remains a fundamental issue in psychology. Previous work has shown that visual short-term memory is organized according to the object of origin, with participants being better at retrieving multiple pieces of information from the same object than from different objects. However, it is not yet clear whether similar memory structures are employed for other modalities, such as audition. Under analogous conditions in the auditory domain, we found that short-term memories for sound can also be organized according to object, with a same-object advantage being demonstrated for the retrieval of information in an auditory scene defined by two complex sounds overlapping in both space and time. Our results provide support for the notion of an auditory object, in addition to the continued identification of similar processing constraints across visual and auditory domains. The identification of modality-independent organizational principles of memory, such as object-based coding, suggests possible mechanisms by which the human processing system remembers multimodal experiences.

The foundations of object permanence: does perceived cohesion determine infants' appreciation of the continuous existence of material objects?

PubMed

Cacchione, Trix

2013-09-01

One of the most fundamental achievements in infants' cognitive development is their appreciation that material objects exist permanently in space and time. Recent findings suggest that infants fail to identify fragmented material objects as continuously existing items. Four experiments assessed 8-12-month-old infants' ability to further represent an object that was fragmented into two or more parts. Results suggest that infants successfully trace the spatiotemporal displacement of fragmented objects, but that their processing of size/quantity-related property information may be affected. This suggests that, contrary to recent claims, 8- to 12-month-old infants can and do appreciate the continuity of fragmented objects. Copyright © 2013 Elsevier B.V. All rights reserved.

Does long-term object priming depend on the explicit detection of object identity at encoding?

PubMed Central

Gomes, Carlos A.; Mayes, Andrew

2015-01-01

It is currently unclear whether objects have to be explicitly identified at encoding for reliable behavioral long-term object priming to occur. We conducted two experiments that investigated long-term object and non-object priming using a selective-attention encoding manipulation that reduces explicit object identification. In Experiment 1, participants either counted dots flashed within an object picture (shallow encoding) or engaged in an animacy task (deep encoding) at study, whereas, at test, they performed an object-decision task. Priming, as measured by reaction times (RTs), was observed for both types of encoding, and was of equivalent magnitude. In Experiment 2, non-object priming (faster RTs for studied relative to unstudied non-objects) was also obtained under the same selective-attention encoding manipulation as in Experiment 1, and the magnitude of the priming effect was equivalent between experiments. In contrast, we observed a linear decrement in recognition memory accuracy across conditions (deep encoding of Experiment 1 > shallow encoding Experiment 1 > shallow encoding of Experiment 2), suggesting that priming was not contaminated by explicit memory strategies. We argue that our results are more consistent with the identification/production framework than the perceptual/conceptual distinction, and we conclude that priming of pictures largely ignored at encoding can be subserved by the automatic retrieval of two types of instances: one at the motor level and another at an object-decision level. PMID:25852594

Multi-objective vs. single-objective calibration of a hydrologic model using single- and multi-objective screening

NASA Astrophysics Data System (ADS)

Mai, Juliane; Cuntz, Matthias; Shafii, Mahyar; Zink, Matthias; Schäfer, David; Thober, Stephan; Samaniego, Luis; Tolson, Bryan

2016-04-01

Hydrologic models are traditionally calibrated against observed streamflow. Recent studies have shown however, that only a few global model parameters are constrained using this kind of integral signal. They can be identified using prior screening techniques. Since different objectives might constrain different parameters, it is advisable to use multiple information to calibrate those models. One common approach is to combine these multiple objectives (MO) into one single objective (SO) function and allow the use of a SO optimization algorithm. Another strategy is to consider the different objectives separately and apply a MO Pareto optimization algorithm. In this study, two major research questions will be addressed: 1) How do multi-objective calibrations compare with corresponding single-objective calibrations? 2) How much do calibration results deteriorate when the number of calibrated parameters is reduced by a prior screening technique? The hydrologic model employed in this study is a distributed hydrologic model (mHM) with 52 model parameters, i.e. transfer coefficients. The model uses grid cells as a primary hydrologic unit, and accounts for processes like snow accumulation and melting, soil moisture dynamics, infiltration, surface runoff, evapotranspiration, subsurface storage and discharge generation. The model is applied in three distinct catchments over Europe. The SO calibrations are performed using the Dynamically Dimensioned Search (DDS) algorithm with a fixed budget while the MO calibrations are achieved using the Pareto Dynamically Dimensioned Search (PA-DDS) algorithm allowing for the same budget. The two objectives used here are the Nash Sutcliffe Efficiency (NSE) of the simulated streamflow and the NSE of the logarithmic transformation. It is shown that the SO DDS results are located close to the edges of the Pareto fronts of the PA-DDS. The MO calibrations are hence preferable due to their supply of multiple equivalent solutions from which the

Pharmacological modulation of abnormal involuntary DOI-induced head twitch response movements in male DBA/2J mice: II. Effects of D3 dopamine receptor selective compounds.

PubMed

Rangel-Barajas, Claudia; Malik, Maninder; Mach, Robert H; Luedtke, Robert R

2015-06-01

We recently reported on the characterization of the hallucinogen 2,5-dimethoxy-4-methylamphetamine's (DOI) ability to elicit a head twitch response (HTR) in DBA/2J mice and the ability of D2 vs. D3 dopamine receptor selective compounds to modulate that response. For these studies, the ability of D3 vs. D2 dopamine receptor selective compounds to attenuate the DOI-dependent HTR was examined. WC 10, a D3 dopamine receptor weak partial agonist with 40-fold binding selectivity for D3 vs. D2 dopamine receptors, produced a dose-dependent decrease in the DOI-induced HTR (IC50 = 3.7 mg/kg). WC 44, a D3 receptor selective full agonist, also inhibited the DOI-induced HTR (IC50 = 5.1 mg/kg). The effect of two D3 receptor selective partial agonists, LAX-4-136 and WW-III-55, were also evaluated. These analogs exhibit 150-fold and 800-fold D3 vs. D2 binding selectivity, respectively. Both compounds inhibited the HTR with similar potency but with different maximum efficacies. At 10 mg/kg WW-III-55 inhibited the HTR by 95%, while LAX-4-136 administration resulted in a 50% reduction. In addition, DOI (5 mg/kg) was administered at various times after LAX-4-136 or WW-III-55 administration to compare the duration of action. The homopiperazine analog LAX-4-136 exhibited greater stability. An assessment of our test compounds on motor performance and coordination was performed using a rotarod test. None of the D3 dopamine receptor selective compounds significantly altered latency to fall, suggesting that these compounds a) did not attenuate the DOI-dependent HTR due to sedative or adverse motor effects and b) may have antipsychotic/antihallucinogenic activity. Copyright © 2015. Published by Elsevier Ltd.

Wikipedia as a gateway to biomedical research: The relative distribution and use of citations in the English Wikipedia

PubMed Central

Willinsky, John M.; Steinberg, Ryan M.; Mietchen, Daniel; Wass, Joseph L.; Dong, Ting

2017-01-01

Wikipedia is a gateway to knowledge. However, the extent to which this gateway ends at Wikipedia or continues via supporting citations is unknown. Wikipedia’s gateway functionality has implications for information design and education, notably in medicine. This study aims to establish benchmarks for the relative distribution and referral (click) rate of citations—as indicated by presence of a Digital Object Identifier (DOI)—from Wikipedia, with a focus on medical citations. DOIs referred from the English Wikipedia in August 2016 were obtained from Crossref.org. Next, based on a DOI’s presence on a WikiProject Medicine page, all DOIs in Wikipedia were categorized as medical (WP:MED) or non-medical (non-WP:MED). Using this categorization, referred DOIs were classified as WP:MED, non-WP:MED, or BOTH, meaning the DOI may have been referred from either category. Data were analyzed using descriptive and inferential statistics. Out of 5.2 million Wikipedia pages, 4.42% (n = 229,857) included at least one DOI. 68,870 were identified as WP:MED, with 22.14% (n = 15,250) featuring one or more DOIs. WP:MED pages featured on average 8.88 DOI citations per page, whereas non-WP:MED pages had on average 4.28 DOI citations. For DOIs only on WP:MED pages, a DOI was referred every 2,283 pageviews and for non-WP:MED pages every 2,467 pageviews. DOIs from BOTH pages accounted for 12% (n = 58,475). The referral of DOI citations found in BOTH could not be assigned to WP:MED or non-WP:MED, as the page from which the referral was made was not provided with the data. While these results cannot provide evidence of greater citation referral from WP:MED than non-WP:MED, they do provide benchmarks to assess strategies for changing referral patterns. These changes might include editors adopting new methods for designing and presenting citations or the introduction of teaching strategies that address the value of consulting citations as a tool for extending learning. PMID:29267345

Bibliographical index of objects observed by IUE

NASA Technical Reports Server (NTRS)

Mead, J. M.; Boggess, A.

1982-01-01

Six astronomical journals were searched and 343 papers describing studies using data obtained with the International Ultraviolet Explorer satellite were identified. From a review of these papers, the names of the astronomical objects discussed were recorded and compiled into a list of 2460 entries, along with each reference, and sorted by object name or catalogue number. This index enables a user to tell immediately where to find published papers describing IUE observation of the objects of interest to him.

Kuiper Belt Objects Along the Pluto-Express Path

NASA Technical Reports Server (NTRS)

Jewitt, David (Principal Investigator)

1997-01-01

The science objective of this work is to identify objects in the Kuiper Belt which will, in the 5 years following Pluto encounter, be close to the flight path of NASA's Pluto Express. Our hope is that we will find a Kuiper Belt object or objects close enough that a spacecraft flyby will be possible. If we find a suitable object, the science yield of Pluto Express will be substantially enhanced. The density of objects in the Kuiper Belt is such that we are reasonably likely to find an object close enough to the flight path that on-board gas thrusters can effect a close encounter.

Connection-based and object-based grouping in multiple-object tracking: A developmental study.

PubMed

Van der Hallen, Ruth; Reusens, Julie; Evers, Kris; de-Wit, Lee; Wagemans, Johan

2018-03-30

Developmental research on Gestalt laws has previously revealed that, even as young as infancy, we are bound to group visual elements into unitary structures in accordance with a variety of organizational principles. Here, we focus on the developmental trajectory of both connection-based and object-based grouping, and investigate their impact on object formation in participants, aged 9-21 years old (N = 113), using a multiple-object tracking paradigm. Results reveal a main effect of both age and grouping type, indicating that 9- to 21-year-olds are sensitive to both connection-based and object-based grouping interference, and tracking ability increases with age. In addition to its importance for typical development, these results provide an informative baseline to understand clinical aberrations in this regard. Statement of contribution What is already known on this subject? The origin of the Gestalt principles is still an ongoing debate: Are they innate, learned over time, or both? Developmental research has revealed how each Gestalt principle has its own trajectory and unique relationship to visual experience. Both connectedness and object-based grouping play an important role in object formation during childhood. What does this study add? The study identifies how sensitivity to connectedness and object-based grouping evolves in individuals, aged 9-21 years old. Using multiple-object tracking, results reveal that the ability to track multiple objects increases with age. These results provide an informative baseline to understand clinical aberrations in different types of grouping. © 2018 The Authors. British Journal of Developmental Psychology published by John Wiley & Sons Ltd on behalf of British Psychological Society.

The Scattered Kuiper Belt Objects

NASA Astrophysics Data System (ADS)

Trujillo, C. A.; Jewitt, D. C.; Luu, J. X.

1999-09-01

We describe a continuing survey of the Kuiper Belt conducted at the 3.6-m Canada France Hawaii Telescope on Mauna Kea, Hawaii. The survey employs a 12288 x 8192 pixel CCD mosaic to image the sky to red magnitude 24. All detected objects are targeted for systematic follow-up observations, allowing us to determine their orbital characteristics. Three new members of the rare Scattered Kuiper Belt Object class have been identified, bringing the known population of such objects to four. The SKBOs are thought to have been scattered outward by Neptune, and are a potential source of the short-period comets. Using a Maximum Likelihood method, we place observational constraints on the total number and mass of the SKBOs.

Objectively classifying Southern Hemisphere extratropical cyclones

NASA Astrophysics Data System (ADS)

Catto, Jennifer

2016-04-01

There has been a long tradition in attempting to separate extratropical cyclones into different classes depending on their cloud signatures, airflows, synoptic precursors, or upper-level flow features. Depending on these features, the cyclones may have different impacts, for example in their precipitation intensity. It is important, therefore, to understand how the distribution of different cyclone classes may change in the future. Many of the previous classifications have been performed manually. In order to be able to evaluate climate models and understand how extratropical cyclones might change in the future, we need to be able to use an automated method to classify cyclones. Extratropical cyclones have been identified in the Southern Hemisphere from the ERA-Interim reanalysis dataset with a commonly used identification and tracking algorithm that employs 850 hPa relative vorticity. A clustering method applied to large-scale fields from ERA-Interim at the time of cyclone genesis (when the cyclone is first detected), has been used to objectively classify identified cyclones. The results are compared to the manual classification of Sinclair and Revell (2000) and the four objectively identified classes shown in this presentation are found to match well. The relative importance of diabatic heating in the clusters is investigated, as well as the differing precipitation characteristics. The success of the objective classification shows its utility in climate model evaluation and climate change studies.

Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator

PubMed Central

Jung, Jennifer; Nayak, Arnab; Schaeffer, Véronique; Starzetz, Tatjana; Kirsch, Achim K; Müller, Stefan; Dikic, Ivan; Mittelbronn, Michel; Behrends, Christian

2017-01-01

Autophagy is an intracellular recycling and degradation pathway that depends on membrane trafficking. Rab GTPases are central for autophagy but their regulation especially through the activity of Rab GEFs remains largely elusive. We employed a RNAi screen simultaneously monitoring different populations of autophagosomes and identified 34 out of 186 Rab GTPase, GAP and GEF family members as potential autophagy regulators, amongst them SMCR8. SMCR8 uses overlapping binding regions to associate with C9ORF72 or with a C9ORF72-ULK1 kinase complex holo-assembly, which function in maturation and formation of autophagosomes, respectively. While focusing on the role of SMCR8 during autophagy initiation, we found that kinase activity and gene expression of ULK1 are increased upon SMCR8 depletion. The latter phenotype involved association of SMCR8 with the ULK1 gene locus. Global mRNA expression analysis revealed that SMCR8 regulates transcription of several other autophagy genes including WIPI2. Collectively, we established SMCR8 as multifaceted negative autophagy regulator. DOI: http://dx.doi.org/10.7554/eLife.23063.001 PMID:28195531

Three new BL Lacertae objects in the Palomar-Green survey

NASA Technical Reports Server (NTRS)

Fleming, Thomas A.; Green, Richard F.; Jannuzi, Buell T.; Liebert, James; Smith, Paul S.; Fink, Henner

1993-01-01

We have identified three BL Lacertae objects in the Palomar-Green Survey which were previously misclassified as DC white dwarfs, namely PG 1246+586, PG 1424+240, and PG 1437+398. Our reclassification is based on the detection of these objects as x-ray sources in the ROSAT all-sky survey and upon our subsequent detection of intrinsic linearly polarized and variable optical emission from these sources. As a result of the ROSAT survey, the number of identified BL Lac objects in the Palomar-Green catalog of UV excess objects has been doubled. Corrected optical positions are presented for PG 1246+586 and PG 1437+398.

THE DERIVATION, ANALYSIS, AND CLASSIFICATION OF INSTRUCTIONAL OBJECTIVES.

ERIC Educational Resources Information Center

AMMERMAN, HARRY L.; MELCHING, WILLIAM H.

THIS REPORT EXAMINES THE METHODS, TERMS, AND CRITERIA ASSOCIATED WITH THE DETERMINATION OF STUDENT PERFORMANCE OBJECTIVES. SELECTED EDUCATIONAL AND TRAINING RESEARCH LITERATURE WAS REVIEWED TO IDENTIFY PROCEDURES CURRENTLY USED IN DETERMINING INSTRUCTIONAL OBJECTIVES. A SURVEY OF EIGHT ARMY SERVICE SCHOOLS WAS CONDUCTED TO DETERMINE PROCEDURES…

Mapping Robots to Therapy and Educational Objectives for Children with Autism Spectrum Disorder.

PubMed

Huijnen, Claire A G J; Lexis, Monique A S; Jansens, Rianne; de Witte, Luc P

2016-06-01

The aim of this study was to increase knowledge on therapy and educational objectives professionals work on with children with autism spectrum disorder (ASD) and to identify corresponding state of the art robots. Focus group sessions (n = 9) with ASD professionals (n = 53) from nine organisations were carried out to create an objectives overview, followed by a systematic literature study to identify state of the art robots matching these objectives. Professionals identified many ASD objectives (n = 74) in 9 different domains. State of the art robots addressed 24 of these objectives in 8 domains. Robots can potentially be applied to a large scope of objectives for children with ASD. This objectives overview functions as a base to guide development of robot interventions for these children.

23 CFR 657.7 - Objective.

Code of Federal Regulations, 2010 CFR

2010-04-01

... of an enforcement process which identifies vehicles of excessive size and weight and provides a... 23 Highways 1 2010-04-01 2010-04-01 false Objective. 657.7 Section 657.7 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION ENGINEERING AND TRAFFIC OPERATIONS CERTIFICATION OF SIZE AND WEIGHT...

Rethinking Trends in Instructional Objectives: Exploring the Alignment of Objectives with Activities and Assessment in Higher Education--A Case Study

ERIC Educational Resources Information Center

Yamanaka, Akio; Wu, Leon Yufeng

2014-01-01

This study explored higher education level syllabi to identify trends in educational objectives. Bloom's Taxonomy and various strategic models were used to classify 714 objectives from 114 sections of courses administered through a Midwest teacher education institution in the United States. 1229 verbs and verb phrases were classified through the…

An evaluation of object-oriented image analysis techniques to identify motorized vehicle effects in semi-arid to arid ecosystems of the American West

USGS Publications Warehouse

Mladinich, C.

2010-01-01

Human disturbance is a leading ecosystem stressor. Human-induced modifications include transportation networks, areal disturbances due to resource extraction, and recreation activities. High-resolution imagery and object-oriented classification rather than pixel-based techniques have successfully identified roads, buildings, and other anthropogenic features. Three commercial, automated feature-extraction software packages (Visual Learning Systems' Feature Analyst, ENVI Feature Extraction, and Definiens Developer) were evaluated by comparing their ability to effectively detect the disturbed surface patterns from motorized vehicle traffic. Each package achieved overall accuracies in the 70% range, demonstrating the potential to map the surface patterns. The Definiens classification was more consistent and statistically valid. Copyright ?? 2010 by Bellwether Publishing, Ltd. All rights reserved.

Children's Comprehension of Object Relative Sentences: It's Extant Language Knowledge That Matters, Not Domain-General Working Memory.

PubMed

Rusli, Yazmin Ahmad; Montgomery, James W

2017-10-17

The aim of this study was to determine whether extant language (lexical) knowledge or domain-general working memory is the better predictor of comprehension of object relative sentences for children with typical development. We hypothesized that extant language knowledge, not domain-general working memory, is the better predictor. Fifty-three children (ages 9-11 years) completed a word-level verbal working-memory task, indexing extant language (lexical) knowledge; an analog nonverbal working-memory task, representing domain-general working memory; and a hybrid sentence comprehension task incorporating elements of both agent selection and cross-modal picture-priming paradigms. Images of the agent and patient were displayed at the syntactic gap in the object relative sentences, and the children were asked to select the agent of the sentence. Results of general linear modeling revealed that extant language knowledge accounted for a unique 21.3% of variance in the children's object relative sentence comprehension over and above age (8.3%). Domain-general working memory accounted for a nonsignificant 1.6% of variance. We interpret the results to suggest that extant language knowledge and not domain-general working memory is a critically important contributor to children's object relative sentence comprehension. Results support a connectionist view of the association between working memory and object relative sentence comprehension. https://doi.org/10.23641/asha.5404573.

Health Care Financial Management: Curriculum Objectives and Bibliography.

ERIC Educational Resources Information Center

Zelman, William N., Ed.; And Others

Curriculum objectives for health care financial management, a bibliography and examples of financial management curricula are presented. The outline of curriculum objectives identifies a core of knowledge and skills in financial management that health administration students might obtain in their academic training. The outline's content is divided…

Identifying Objective Physiological Markers and Modifiable Behaviors for Self-Reported Stress and Mental Health Status Using Wearable Sensors and Mobile Phones: Observational Study.

PubMed

Sano, Akane; Taylor, Sara; McHill, Andrew W; Phillips, Andrew Jk; Barger, Laura K; Klerman, Elizabeth; Picard, Rosalind

2018-06-08

Wearable and mobile devices that capture multimodal data have the potential to identify risk factors for high stress and poor mental health and to provide information to improve health and well-being. We developed new tools that provide objective physiological and behavioral measures using wearable sensors and mobile phones, together with methods that improve their data integrity. The aim of this study was to examine, using machine learning, how accurately these measures could identify conditions of self-reported high stress and poor mental health and which of the underlying modalities and measures were most accurate in identifying those conditions. We designed and conducted the 1-month SNAPSHOT study that investigated how daily behaviors and social networks influence self-reported stress, mood, and other health or well-being-related factors. We collected over 145,000 hours of data from 201 college students (age: 18-25 years, male:female=1.8:1) at one university, all recruited within self-identified social groups. Each student filled out standardized pre- and postquestionnaires on stress and mental health; during the month, each student completed twice-daily electronic diaries (e-diaries), wore two wrist-based sensors that recorded continuous physical activity and autonomic physiology, and installed an app on their mobile phone that recorded phone usage and geolocation patterns. We developed tools to make data collection more efficient, including data-check systems for sensor and mobile phone data and an e-diary administrative module for study investigators to locate possible errors in the e-diaries and communicate with participants to correct their entries promptly, which reduced the time taken to clean e-diary data by 69%. We constructed features and applied machine learning to the multimodal data to identify factors associated with self-reported poststudy stress and mental health, including behaviors that can be possibly modified by the individual to improve

Object detection and tracking system

DOEpatents

Ma, Tian J.

2017-05-30

Methods and apparatuses for analyzing a sequence of images for an object are disclosed herein. In a general embodiment, the method identifies a region of interest in the sequence of images. The object is likely to move within the region of interest. The method divides the region of interest in the sequence of images into sections and calculates signal-to-noise ratios for a section in the sections. A signal-to-noise ratio for the section is calculated using the section in the image, a prior section in a prior image to the image, and a subsequent section in a subsequent image to the image. The signal-to-noise ratios are for potential velocities of the object in the section. The method also selects a velocity from the potential velocities for the object in the section using a potential velocity in the potential velocities having a highest signal-to-noise ratio in the signal-to-noise ratios.

Magnetic Resonance Spectroscopy: An Objective Modality to Identify the Pathology of Breast Neoplasms

DTIC Science & Technology

1999-05-01

Zealand Journal or Surgery Appendix IV: Attached Manuscript published in Life Sciences Appendix V: Attached Figures 1-13 Appendix VI: Attached Tables 1... early diagnosis and effective management. The triage of mammography, clinical examination and fine needle aspiration biopsy is currently used to...identify early breast cancers. Magnetic resonance imaging (MRI) has now been added to select women with breast abnormalities requiring biopsy. However

The role of judgment frames and task precision in object attention: Reduced template sharpness limits dual-object performance.

PubMed

Liu, Shiau-Hua; Dosher, Barbara Anne; Lu, Zhong-Lin

2009-06-01

Multiple attributes of a single-object are often processed more easily than attributes of different objects-a phenomenon associated with object attention. Here we investigate the influence of two factors, judgment frames and judgment precision, on dual-object report deficits as an index of object attention. [Han, S., Dosher, B., & Lu, Z.-L. (2003). Object attention revisited: Identifying mechanisms and boundary conditions. Psychological Science, 14, 598-604] predicted that consistency of the frame for judgments about two separate objects could reduce or eliminate the expression of object attention limitations. The current studies examine the effects of judgment frames and of task precision in orientation identification and find that dual-object report deficits within one feature are indeed affected modestly by the congruency of the judgments and more substantially by the required precision of judgments. The observed dual-object deficits affected contrast thresholds for incongruent frame conditions and for high precision judgments and reduce psychometric asymptotes. These dual-object deficits reflect a combined effect of multiplicative noise and external noise exclusion in dual-object conditions, both related to the effects of attention on the tuning of perceptual templates. These results have implications for modification of object attention theory, for understanding limitations on concurrent tasks.

Object-Oriented Programming When Developing Software in Geology and Geophysics

NASA Astrophysics Data System (ADS)

Ahmadulin, R. K.; Bakanovskaya, L. N.

2017-01-01

The paper reviews the role of object-oriented programming when developing software in geology and geophysics. Main stages have been identified at which it is worthwhile to apply principles of object-oriented programming when developing software in geology and geophysics. The research was based on a number of problems solved in Geology and Petroleum Production Institute. Distinctive features of these problems are given and areas of application of the object-oriented approach are identified. Developing applications in the sphere of geology and geophysics has shown that the process of creating such products is simplified due to the use of object-oriented programming, firstly when designing structures for data storage and graphical user interfaces.

Parallel object-oriented data mining system

DOEpatents

Kamath, Chandrika; Cantu-Paz, Erick

2004-01-06

A data mining system uncovers patterns, associations, anomalies and other statistically significant structures in data. Data files are read and displayed. Objects in the data files are identified. Relevant features for the objects are extracted. Patterns among the objects are recognized based upon the features. Data from the Faint Images of the Radio Sky at Twenty Centimeters (FIRST) sky survey was used to search for bent doubles. This test was conducted on data from the Very Large Array in New Mexico which seeks to locate a special type of quasar (radio-emitting stellar object) called bent doubles. The FIRST survey has generated more than 32,000 images of the sky to date. Each image is 7.1 megabytes, yielding more than 100 gigabytes of image data in the entire data set.

Twitter Conversation Patterns Related to Research Papers

ERIC Educational Resources Information Center

Nelhans, Gustaf; Lorentzen, David Gunnarsson

2016-01-01

Introduction: This paper deals with what academic texts and datasets are referred to and discussed on Twitter. We used document object identifiers as references to these items. Method: We streamed tweets from the Twitter application programming interface including the strings "dx" and "doi" while simultaneously streaming tweets…

Setting a research question, aim and objective.

PubMed

Doody, Owen; Bailey, Maria E

2016-03-01

To describe the development of a research question, aim and objective. The first steps of any study are developing the research question, aim and objective. Subsequent steps develop from these and they govern the researchers' choice of population, setting, data to be collected and time period for the study. Clear, succinctly posed research questions, aims and objectives are essential if studies are to be successful. Researchers developing their research questions, aims and objectives generally experience difficulties. They are often overwhelmed trying to convert what they see as a relevant issue from practice into research. This necessitates engaging with the relevant published literature and knowledgeable people. This paper identifies the issues to be considered when developing a research question, aim and objective. Understanding these considerations will enable researchers to effectively present their research question, aim and objective. To conduct successful studies, researchers should develop clear research questions, aims and objectives.

Kuiper Belt Objects Along the Pluto Express Path

NASA Technical Reports Server (NTRS)

Jewitt, David C.

1998-01-01

The science objective of this work was to identify objects in the Kuiper Belt which will, in the 5 years following Pluto encounter, be close to the flight path of NASA's Pluto-Kuiper Express. Currently, launch is scheduled for 2004 with a flight time of about 1 decade. Early identification of post-Pluto targets is important for mission design and orbit refinement. An object or objects close enough to the flight path can be visited and studied at high resolution, using only residual gas in the thrusters to affect a close encounter.

A metadata schema for data objects in clinical research.

PubMed

Canham, Steve; Ohmann, Christian

2016-11-24

A large number of stakeholders have accepted the need for greater transparency in clinical research and, in the context of various initiatives and systems, have developed a diverse and expanding number of repositories for storing the data and documents created by clinical studies (collectively known as data objects). To make the best use of such resources, we assert that it is also necessary for stakeholders to agree and deploy a simple, consistent metadata scheme. The relevant data objects and their likely storage are described, and the requirements for metadata to support data sharing in clinical research are identified. Issues concerning persistent identifiers, for both studies and data objects, are explored. A scheme is proposed that is based on the DataCite standard, with extensions to cover the needs of clinical researchers, specifically to provide (a) study identification data, including links to clinical trial registries; (b) data object characteristics and identifiers; and (c) data covering location, ownership and access to the data object. The components of the metadata scheme are described. The metadata schema is proposed as a natural extension of a widely agreed standard to fill a gap not tackled by other standards related to clinical research (e.g., Clinical Data Interchange Standards Consortium, Biomedical Research Integrated Domain Group). The proposal could be integrated with, but is not dependent on, other moves to better structure data in clinical research.

Monocular Vision-Based Underwater Object Detection

PubMed Central

Zhang, Zhen; Dai, Fengzhao; Bu, Yang; Wang, Huibin

2017-01-01

In this paper, we propose an underwater object detection method using monocular vision sensors. In addition to commonly used visual features such as color and intensity, we investigate the potential of underwater object detection using light transmission information. The global contrast of various features is used to initially identify the region of interest (ROI), which is then filtered by the image segmentation method, producing the final underwater object detection results. We test the performance of our method with diverse underwater datasets. Samples of the datasets are acquired by a monocular camera with different qualities (such as resolution and focal length) and setups (viewing distance, viewing angle, and optical environment). It is demonstrated that our ROI detection method is necessary and can largely remove the background noise and significantly increase the accuracy of our underwater object detection method. PMID:28771194

Target-object integration, attention distribution, and object orientation interactively modulate object-based selection.

PubMed

Al-Janabi, Shahd; Greenberg, Adam S

2016-10-01

The representational basis of attentional selection can be object-based. Various studies have suggested, however, that object-based selection is less robust than spatial selection across experimental paradigms. We sought to examine the manner by which the following factors might explain this variation: Target-Object Integration (targets 'on' vs. part 'of' an object), Attention Distribution (narrow vs. wide), and Object Orientation (horizontal vs. vertical). In Experiment 1, participants discriminated between two targets presented 'on' an object in one session, or presented as a change 'of' an object in another session. There was no spatial cue-thus, attention was initially focused widely-and the objects were horizontal or vertical. We found evidence of object-based selection only when targets constituted a change 'of' an object. Additionally, object orientation modulated the sign of object-based selection: We observed a same-object advantage for horizontal objects, but a same-object cost for vertical objects. In Experiment 2, an informative cue preceded a single target presented 'on' an object or as a change 'of' an object (thus, attention was initially focused narrowly). Unlike in Experiment 1, we found evidence of object-based selection independent of target-object integration. We again found that the sign of selection was modulated by the objects' orientation. This result may reflect a meridian effect, which emerged due to anisotropies in the cortical representations when attention is oriented endogenously. Experiment 3 revealed that object orientation did not modulate object-based selection when attention was oriented exogenously. Our findings suggest that target-object integration, attention distribution, and object orientation modulate object-based selection, but only in combination.

Structural Elements in a Persistent Identifier Infrastructure and Resulting Benefits for the Earth Science Community

NASA Astrophysics Data System (ADS)

Weigel, T.; Toussaiant, F.; Stockhause, M.; Höck, H.; Kindermann, S.; Lautenschlager, M.; Ludwig, T.

2012-12-01

We propose a wide adoption of structural elements (typed links, collections, trees) in the Handle System to improve identification and access of scientific data, metadata and software as well as traceability of data provenance. Typed links target the issue of data provenance as a means to assess the quality of scientific data. Data provenance is seen here as a directed acyclic graph with nodes representing data and vertices representing derivative operations (Moreau 2010). Landing pages can allow a human user to explore the provenance graph back to the primary unprocessed data, thereby also giving credit to the original data producer. As in Earth System Modeling no single infrastructure with complete data lifecycle coverage exists, we propose to split the problem domain in two parts. Project-specific infrastructures such as the German project C3-Grid or the Earth System Grid Federation (ESGF) for CMIP5 data are aware of data and data operations (Toussaint et al. 2012) and can thus detect and accumulate single nodes and vertices in the provenance graph, assigning Handles to data, metadata and software. With a common schema for typed links, the provenance graph is established as downstream infrastructures refer incoming Handles. Data in this context is for example hierarchically structured Earth System model output data, which receives DataCite DOIs only for the most coarse-granular elements. Using Handle tree structures, the lower levels of the hierarchy can also receive Handles, allowing authors to more precisely identify the data they used (Lawrence et al. 2011). We can e.g. define a DOI for just the 2m-temperature variable of CMIP5 data across many CMIP5 experiments or a DOI for model and observational data coming from different sources. The structural elements should be implemented through Handle values at the Handle infrastructure level for two reasons. Handle values are more durable than downstream websites or databases, and thus the provenance chain does not

Cosmic Dust Collection Facility: Scientific objectives and programmatic relations

NASA Technical Reports Server (NTRS)

Hoerz, Fred (Editor); Brownlee, D. E.; Bunch, T. E.; Grounds, D.; Grun, E.; Rummel, Y.; Quaide, W. L.; Walker, R. M.

1990-01-01

The science objectives are summarized for the Cosmic Dust Collection Facility (CDCF) on Space Station Freedom and these objectives are related to ongoing science programs and mission planning within NASA. The purpose is to illustrate the potential of the CDCF project within the broad context of early solar system sciences that emphasize the study of primitive objects in state-of-the-art analytical and experimental laboratories on Earth. Current knowledge about the sources of cosmic dust and their associated orbital dynamics is examined, and the results are reviewed of modern microanalytical investigations of extraterrestrial dust particles collected on Earth. Major areas of scientific inquiry and uncertainty are identified and it is shown how CDCF will contribute to their solution. General facility and instrument concepts that need to be pursued are introduced, and the major development tasks that are needed to attain the scientific objectives of the CDCF project are identified.

Inventory of water objects for purposes of development objectives and design of natural frame of Kazan (Russia)

NASA Astrophysics Data System (ADS)

Mingazova, N. M.

2018-01-01

The article is devoted to the results of the inventory and certification of water objects in the city of Kazan in 2007-2017. Inventory of water objects contributes to the formation of the natural framework of the city, improvement of the quality of the environment, preservation of the local gene pool of flora and fauna in urban conditions. During the research, 236 small lakes, rivers and their tributaries, as well as wetlands, were identified. The environmental passports were developed for each of them. Registries of water bodies were developed for administrative regions. The inventory and certification of water objects are an effective measure in the conservation of lakes and rivers in urban conditions.

Estimation of position resolution for DOI-PET detector using diameter 0.2 mm WLS fibers [ANIMMA--2015-IO-x5

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kaneko, Naomi; Ito, H.; Han, S.

We have been developing a submillimeter resolution and low-cost DOI-PET detector using wavelength shifting fibers (WLSF), scintillating crystal plates and MPPCs (Hamamatsu Photonics). Conventional design of DOI-PET detectors had approximately mm{sup 3} of resolution by using some scintillating blocks with a volume of 1 mm{sup 3}, which detects gamma-ray. They are expensive due to difficulties in processing scintillating crystals and a large number of photo-detectors, and these technologies are likely to reach the limit of the resolution. Development of a lower cost DOI-PET detector with higher resolution is challenging to popularize the PET diagnosis. We propose two type of PETmore » detector. One is a whole body PET system, and the other is a PET system for brain or small animals. Each PET system consists 6 blocks. The former consists of 6 layers of crystal plates with 300 mm x 300 mm x 4 mm. The latter consists of 16 crystal layers, forming 4 x 4 crystal arrays. The size of the crystal plate is 40 mm x 40 mm x 1 mm. Wavelength shifting fiber (WLSF) sheets are attached to above and up and down side of crystal planes. The whole PET system has 8 MPPCs attached on each side. For the brain PET detector, 9 WLSF fibers are attached on the each side. The expected position resolution would be less than 1 mm at the former system. We have performed an experimental performance estimation for the system component using {sup 22}Na radioactive source. We achieved a collection efficiency of 10% using the WLSF sheet and Ce:Gd{sub 3}(Al,Ga){sub 5}O{sub 12} (GAGG) crystals at 511 keV. The linear relationship between reconstruction position and incident position was obtained, and a resolution of 0.7 mm (FWHM) for x-axis of DOI by the WLSF readout was achieved. (authors)« less

"Geriatricizing" Hospitalists: Identifying Educational Opportunities

ERIC Educational Resources Information Center

Friedman, Susan M.; Gillespie, Suzanne M.; Medina-Walpole, Annette M.; Caprio, Thomas V.; Karuza, Jurgis; McCann, Robert M.

2013-01-01

The objective of this study was to identify differences between geriatricians and hospitalists in caring for hospitalized older adults, so as to inform faculty development programs that have the goal of improving older patient care. Eleven hospitalists and 13 geriatricians were surveyed regarding knowledge, confidence, and practice patterns in…

Neural Correlates of the Perception for Novel Objects

PubMed Central

Zhang, Hao; Liu, Jia; Zhang, Qinglin

2013-01-01

Perception of novel objects is of enormous importance in our lives. People have to perceive or understand novel objects when seeing an original painting, admiring an unconventional construction, and using an inventive device. However, very little is known about neural mechanisms underlying the perception for novel objects. Perception of novel objects relies on the integration of unusual features of novel objects in order to identify what such objects are. In the present study, functional Magnetic Resonance Imaging (MRI) was employed to investigate neural correlates of perception of novel objects. The neuroimaging data on participants engaged in novel object viewing versus ordinary object viewing revealed that perception of novel objects involves significant activation in the left precuneus (Brodmann area 7) and the right visual cortex. The results suggest that the left precuneus is associated with the integration of unusual features of novel objects, while the right visual cortex is sensitive to the detection of such features. Our findings highlight the left precuneus as a crucial component of the neural circuitry underlying perception of novel objects. PMID:23646167

Non-coding cancer driver candidates identified with a sample- and position-specific model of the somatic mutation rate

PubMed Central

Juul, Malene; Bertl, Johanna; Guo, Qianyun; Nielsen, Morten Muhlig; Świtnicki, Michał; Hornshøj, Henrik; Madsen, Tobias; Hobolth, Asger; Pedersen, Jakob Skou

2017-01-01

Non-coding mutations may drive cancer development. Statistical detection of non-coding driver regions is challenged by a varying mutation rate and uncertainty of functional impact. Here, we develop a statistically founded non-coding driver-detection method, ncdDetect, which includes sample-specific mutational signatures, long-range mutation rate variation, and position-specific impact measures. Using ncdDetect, we screened non-coding regulatory regions of protein-coding genes across a pan-cancer set of whole-genomes (n = 505), which top-ranked known drivers and identified new candidates. For individual candidates, presence of non-coding mutations associates with altered expression or decreased patient survival across an independent pan-cancer sample set (n = 5454). This includes an antigen-presenting gene (CD1A), where 5’UTR mutations correlate significantly with decreased survival in melanoma. Additionally, mutations in a base-excision-repair gene (SMUG1) correlate with a C-to-T mutational-signature. Overall, we find that a rich model of mutational heterogeneity facilitates non-coding driver identification and integrative analysis points to candidates of potential clinical relevance. DOI: http://dx.doi.org/10.7554/eLife.21778.001 PMID:28362259

Method for contour extraction for object representation

DOEpatents

Skourikhine, Alexei N.; Prasad, Lakshman

2005-08-30

Contours are extracted for representing a pixelated object in a background pixel field. An object pixel is located that is the start of a new contour for the object and identifying that pixel as the first pixel of the new contour. A first contour point is then located on the mid-point of a transition edge of the first pixel. A tracing direction from the first contour point is determined for tracing the new contour. Contour points on mid-points of pixel transition edges are sequentially located along the tracing direction until the first contour point is again encountered to complete tracing the new contour. The new contour is then added to a list of extracted contours that represent the object. The contour extraction process associates regions and contours by labeling all the contours belonging to the same object with the same label.

Multi-Objective Community Detection Based on Memetic Algorithm

PubMed Central

2015-01-01

Community detection has drawn a lot of attention as it can provide invaluable help in understanding the function and visualizing the structure of networks. Since single objective optimization methods have intrinsic drawbacks to identifying multiple significant community structures, some methods formulate the community detection as multi-objective problems and adopt population-based evolutionary algorithms to obtain multiple community structures. Evolutionary algorithms have strong global search ability, but have difficulty in locating local optima efficiently. In this study, in order to identify multiple significant community structures more effectively, a multi-objective memetic algorithm for community detection is proposed by combining multi-objective evolutionary algorithm with a local search procedure. The local search procedure is designed by addressing three issues. Firstly, nondominated solutions generated by evolutionary operations and solutions in dominant population are set as initial individuals for local search procedure. Then, a new direction vector named as pseudonormal vector is proposed to integrate two objective functions together to form a fitness function. Finally, a network specific local search strategy based on label propagation rule is expanded to search the local optimal solutions efficiently. The extensive experiments on both artificial and real-world networks evaluate the proposed method from three aspects. Firstly, experiments on influence of local search procedure demonstrate that the local search procedure can speed up the convergence to better partitions and make the algorithm more stable. Secondly, comparisons with a set of classic community detection methods illustrate the proposed method can find single partitions effectively. Finally, the method is applied to identify hierarchical structures of networks which are beneficial for analyzing networks in multi-resolution levels. PMID:25932646

Multi-objective community detection based on memetic algorithm.

PubMed

Wu, Peng; Pan, Li

2015-01-01

Community detection has drawn a lot of attention as it can provide invaluable help in understanding the function and visualizing the structure of networks. Since single objective optimization methods have intrinsic drawbacks to identifying multiple significant community structures, some methods formulate the community detection as multi-objective problems and adopt population-based evolutionary algorithms to obtain multiple community structures. Evolutionary algorithms have strong global search ability, but have difficulty in locating local optima efficiently. In this study, in order to identify multiple significant community structures more effectively, a multi-objective memetic algorithm for community detection is proposed by combining multi-objective evolutionary algorithm with a local search procedure. The local search procedure is designed by addressing three issues. Firstly, nondominated solutions generated by evolutionary operations and solutions in dominant population are set as initial individuals for local search procedure. Then, a new direction vector named as pseudonormal vector is proposed to integrate two objective functions together to form a fitness function. Finally, a network specific local search strategy based on label propagation rule is expanded to search the local optimal solutions efficiently. The extensive experiments on both artificial and real-world networks evaluate the proposed method from three aspects. Firstly, experiments on influence of local search procedure demonstrate that the local search procedure can speed up the convergence to better partitions and make the algorithm more stable. Secondly, comparisons with a set of classic community detection methods illustrate the proposed method can find single partitions effectively. Finally, the method is applied to identify hierarchical structures of networks which are beneficial for analyzing networks in multi-resolution levels.

System and method for detecting a faulty object in a system

DOEpatents

Gunnels, John A.; Gustavson, Fred Gehrung; Engle, Robert Daniel

2010-12-14

A method (and system) for detecting at least one faulty object in a system including a plurality of objects in communication with each other in an n-dimensional architecture, includes probing a first plane of objects in the n-dimensional architecture and probing at least one other plane of objects in the n-dimensional architecture which would result in identifying a faulty object in the system.

System and method for detecting a faulty object in a system

DOEpatents

Gunnels, John A [Brewster, NY; Gustavson, Fred Gehrung [Briarcliff Manor, NY; Engle, Robert Daniel [St. Louis, MO

2009-03-17

A method (and system) for detecting at least one faulty object in a system including a plurality of objects in communication with each other in an n-dimensional architecture, includes probing a first plane of objects in the n-dimensional architecture and probing at least one other plane of objects in the n-dimensional architecture which would result in identifying a faulty object in the system.

Object-based benefits without object-based representations.

PubMed

Fougnie, Daryl; Cormiea, Sarah M; Alvarez, George A

2013-08-01

Influential theories of visual working memory have proposed that the basic units of memory are integrated object representations. Key support for this proposal is provided by the same object benefit: It is easier to remember multiple features of a single object than the same set of features distributed across multiple objects. Here, we replicate the object benefit but demonstrate that features are not stored as single, integrated representations. Specifically, participants could remember 10 features better when arranged in 5 objects compared to 10 objects, yet memory for one object feature was largely independent of memory for the other object feature. These results rule out the possibility that integrated representations drive the object benefit and require a revision of the concept of object-based memory representations. We propose that working memory is object-based in regard to the factors that enhance performance but feature based in regard to the level of representational failure. PsycINFO Database Record (c) 2013 APA, all rights reserved.

Objective Use of Climate Indices to Inform Ensemble Streamflow Forecasts in the Columbia River Basin - An Initial Review

NASA Astrophysics Data System (ADS)

Pytlak, E.; McManamon, A.; Hughes, S. P.; Van Der Zweep, R. A.; Butcher, P.; Karafotias, C.; Beckers, J.; Welles, E.

2016-12-01

value in incorporating objectively-identified climate signals into ESP-based streamflow forecasts.Beckers, J. V. L., Weerts, A. H., Tijdeman, E., and Welles, E.: ENSO-Conditioned Weather Resampling Method for Seasonal Ensemble Streamflow Prediction, Hydrol. Earth Syst. Sci. Discuss., doi:10.5194/hess-2016-72, in review, 2016.

Consent Agreement with the US Department of Interior (DOI), Bureau of Indian Affairs (BIA) and Bureau of Indian Education (BIE)

EPA Pesticide Factsheets

Consent Agreement between EPA and the Department of Interior (DOI), Bureau of Indian Affairs and Bureau of Indian Education (BIE) for violations of RCRA, CAA, TSCA, AHERA, and SDWA. These violations involve schools and public water systems.

Objects of attention, objects of perception.

PubMed

Avrahami, J

1999-11-01

Four experiments were conducted, to explore the notion of objects in perception. Taking as a starting point the effects of display content on rapid attention transfer and manipulating curvature, closure, and processing time, a link between objects of attention and objects of perception is proposed. In Experiment 1, a number of parallel, equally spaced, straight lines facilitated attention transfer along the lines, relative to transfer across the lines. In Experiment 2, with curved, closed-contour shapes, no "same-object" facilitation was observed. However, when a longer time interval was provided, in Experiment 3, a same-object advantage started to emerge. In Experiment 4, using the same curved shapes but in a non-speeded distance estimation task, a strong effect of objects was observed. It is argued that attention transfer is facilitated by line tracing but that line tracing is encouraged by objects.

Accessible Near-Earth Objects (NEOs)

NASA Technical Reports Server (NTRS)

Barbee, Brent W.

2015-01-01

Near Earth Objects (NEOs) are asteroids and comets whose orbits are in close proximity to Earth's orbit; specifically, they have perihelia less than 1.3 astronomical units. NEOs particularly near Earth asteroids (NEAs) are identified as potential destinations for future human exploration missions. In this presentation I provide an overview of the current state of knowledge regarding the astrodynamical accessibility of NEAs according to NASA's Near Earth Object Human Space Flight Accessible Targets Study (NHATS). I also investigate the extremes of NEA accessibility using case studies and illuminate the fact that a space-based survey for NEOs is essential to expanding the set of known accessible NEAs for future human exploration missions.

Persistent Identifiers in Earth science data management environments

NASA Astrophysics Data System (ADS)

Weigel, Tobias; Stockhause, Martina; Lautenschlager, Michael

2014-05-01

Globally resolvable Persistent Identifiers (PIDs) that carry additional context information (which can be any form of metadata) are increasingly used by data management infrastructures for fundamental tasks. The notion of a Persistent Identifier is originally an abstract concept that aims to provide identifiers that are quality-controlled and maintained beyond the life time of the original issuer, for example through the use of redirection mechanisms. Popular implementations of the PID concept are for example the Handle System and the DOI System based on it. These systems also move beyond the simple identification concept by providing facilities that can hold additional context information. Not only in the Earth sciences, data managers are increasingly attracted to PIDs because of the opportunities these facilities provide; however, long-term viable principles and mechanisms for efficient organization of PIDs and context information are not yet available or well established. In this respect, promising techniques are to type the information that is associated with PIDs and to construct actionable collections of PIDs. There are two main drivers for extended PID usage: Earth science data management middleware use cases and applications geared towards scientific end-users. Motivating scenarios from data management include hierarchical data and metadata management, consistent data tracking and improvements in the accountability of processes. If PIDs are consistently assigned to data objects, context information can be carried over to subsequent data life cycle stages much easier. This can also ease data migration from one major curation domain to another, e.g. from early dissemination within research communities to formal publication and long-term archival stages, and it can help to document processes across technical and organizational boundaries. For scientific end users, application scenarios include for example more personalized data citation and improvements in the

Diversity Outbred Mice Identify Population-Based Exposure Thresholds and Genetic Factors that Influence Benzene-Induced Genotoxicity

PubMed Central

Gatti, Daniel M.; Morgan, Daniel L.; Kissling, Grace E.; Shockley, Keith R.; Knudsen, Gabriel A.; Shepard, Kim G.; Price, Herman C.; King, Deborah; Witt, Kristine L.; Pedersen, Lars C.; Munger, Steven C.; Svenson, Karen L.; Churchill, Gary A.

2014-01-01

Background Inhalation of benzene at levels below the current exposure limit values leads to hematotoxicity in occupationally exposed workers. Objective We sought to evaluate Diversity Outbred (DO) mice as a tool for exposure threshold assessment and to identify genetic factors that influence benzene-induced genotoxicity. Methods We exposed male DO mice to benzene (0, 1, 10, or 100 ppm; 75 mice/exposure group) via inhalation for 28 days (6 hr/day for 5 days/week). The study was repeated using two independent cohorts of 300 animals each. We measured micronuclei frequency in reticulocytes from peripheral blood and bone marrow and applied benchmark concentration modeling to estimate exposure thresholds. We genotyped the mice and performed linkage analysis. Results We observed a dose-dependent increase in benzene-induced chromosomal damage and estimated a benchmark concentration limit of 0.205 ppm benzene using DO mice. This estimate is an order of magnitude below the value estimated using B6C3F1 mice. We identified a locus on Chr 10 (31.87 Mb) that contained a pair of overexpressed sulfotransferases that were inversely correlated with genotoxicity. Conclusions The genetically diverse DO mice provided a reproducible response to benzene exposure. The DO mice display interindividual variation in toxicity response and, as such, may more accurately reflect the range of response that is observed in human populations. Studies using DO mice can localize genetic associations with high precision. The identification of sulfotransferases as candidate genes suggests that DO mice may provide additional insight into benzene-induced genotoxicity. Citation French JE, Gatti DM, Morgan DL, Kissling GE, Shockley KR, Knudsen GA, Shepard KG, Price HC, King D, Witt KL, Pedersen LC, Munger SC, Svenson KL, Churchill GA. 2015. Diversity Outbred mice identify population-based exposure thresholds and genetic factors that influence benzene-induced genotoxicity. Environ Health Perspect 123:237�

Identification of everyday objects on the basis of Gaborized outline versions

PubMed Central

Sassi, Michaël; Vancleef, Kathleen; Machilsen, Bart; Panis, Sven; Wagemans, Johan

2010-01-01

Using outlines derived from a widely used set of line drawings, we created stimuli geared towards the investigation of contour integration and texture segmentation using shapes of everyday objects. Each stimulus consisted of Gabor elements positioned and oriented curvilinearly along the outline of an object, embedded within a larger Gabor array of homogeneous density. We created six versions of the resulting Gaborized outline stimuli by varying the orientations of elements inside and outside the outline. Data from two experiments, in which participants attempted to identify the objects in the stimuli, provide norms for identifiability and name agreement, and show differences in identifiability between stimulus versions. While there was substantial variability between the individual objects in our stimulus set, further analyses suggest a number of stimulus properties which are generally predictive of identification performance. The stimuli and the accompanying normative data, both available on our website (http://www.gestaltrevision.be/sources/gaboroutlines), provide a useful tool to further investigate contour integration and texture segmentation in both normal and clinical populations, especially when top-down influences on these processes, such as the role of prior knowledge of familiar objects, are of main interest. PMID:23145218

Identification of everyday objects on the basis of Gaborized outline versions.

PubMed

Sassi, Michaël; Vancleef, Kathleen; Machilsen, Bart; Panis, Sven; Wagemans, Johan

2010-01-01

Using outlines derived from a widely used set of line drawings, we created stimuli geared towards the investigation of contour integration and texture segmentation using shapes of everyday objects. Each stimulus consisted of Gabor elements positioned and oriented curvilinearly along the outline of an object, embedded within a larger Gabor array of homogeneous density. We created six versions of the resulting Gaborized outline stimuli by varying the orientations of elements inside and outside the outline. Data from two experiments, in which participants attempted to identify the objects in the stimuli, provide norms for identifiability and name agreement, and show differences in identifiability between stimulus versions. While there was substantial variability between the individual objects in our stimulus set, further analyses suggest a number of stimulus properties which are generally predictive of identification performance. The stimuli and the accompanying normative data, both available on our website (http://www.gestaltrevision.be/sources/gaboroutlines), provide a useful tool to further investigate contour integration and texture segmentation in both normal and clinical populations, especially when top-down influences on these processes, such as the role of prior knowledge of familiar objects, are of main interest.

Atypical antipsychotic clozapine reversed deficit on prepulse inhibition of the acoustic startle reflex produced by microinjection of DOI into the inferior colliculus in rats.

PubMed

de Oliveira, Rodolpho Pereira; Nagaishi, Karen Yuriko; Barbosa Silva, Regina Cláudia

2017-05-15

Dysfunctions of the serotonergic system have been suggested to be important in the neurobiology of schizophrenia. Patients with schizophrenia exhibit deficits in an operational measure of sensorimotor gating: prepulse inhibition (PPI) of startle. PPI is the normal reduction in the startle response caused by a low intensity non-startling stimulus (prepulse) which is presented shortly before the startle stimulus (pulse). The hallucinogen 2,5-dimethoxy-4-iodoamphetamine (DOI), a 5-hydroxytryptamine(HT) 2 receptor agonist disrupted PPI in rats. The inferior colliculus (IC) is a critical nucleus of the auditory pathway mediating acoustic PPI. The activation of the IC by the acoustic prepulse reduces startle magnitude. The present study investigated the role of serotonergic transmission in the IC on the expression of acoustic PPI. For that we investigated whether 5-HT2A receptor activation or blockade would affect this response. Unilateral microinjection of DOI (10μg/0.3μl) into the IC disrupted PPI, while microinjection of the 5-HT2A receptor antagonist ritanserin (4μg/0.3μl), into this structure did not alter PPI. We also examined the ability of the atypical antipsychotic clozapine (5.0mg/kg; I.P.) to reverse the disruption of PPI produced by unilateral microinjections of DOI into the IC of rats. Pretreatment with clozapine blocked DOI-induced disruption of PPI. Altogether, these results suggest that serotonin-mediated mechanisms of the IC are involved in the expression of PPI in rodents and that this response is sensitive to atypical antipsychotic clozapine. Copyright © 2017 Elsevier B.V. All rights reserved.

Object width modulates object-based attentional selection.

PubMed

Nah, Joseph C; Neppi-Modona, Marco; Strother, Lars; Behrmann, Marlene; Shomstein, Sarah

2018-04-24

Visual input typically includes a myriad of objects, some of which are selected for further processing. While these objects vary in shape and size, most evidence supporting object-based guidance of attention is drawn from paradigms employing two identical objects. Importantly, object size is a readily perceived stimulus dimension, and whether it modulates the distribution of attention remains an open question. Across four experiments, the size of the objects in the display was manipulated in a modified version of the two-rectangle paradigm. In Experiment 1, two identical parallel rectangles of two sizes (thin or thick) were presented. Experiments 2-4 employed identical trapezoids (each having a thin and thick end), inverted in orientation. In the experiments, one end of an object was cued and participants performed either a T/L discrimination or a simple target-detection task. Combined results show that, in addition to the standard object-based attentional advantage, there was a further attentional benefit for processing information contained in the thick versus thin end of objects. Additionally, eye-tracking measures demonstrated increased saccade precision towards thick object ends, suggesting that Fitts's Law may play a role in object-based attentional shifts. Taken together, these results suggest that object-based attentional selection is modulated by object width.

Integrating ergonomics into engineering design: the role of objects.

PubMed

Hall-Andersen, Lene Bjerg; Broberg, Ole

2014-05-01

The objective of this study was to explore the role of objects in integrating ergonomic knowledge in engineering design processes. An engineering design case was analyzed using the theoretical concepts of boundary objects and intermediary objects: Boundary objects facilitate collaboration between different knowledge domains, while the aim of an intermediary object is to circulate knowledge and thus produce a distant effect. Adjustable layout drawings served as boundary objects and had a positive impact on the dialog between an ergonomist and designers. An ergonomic guideline document was identified as an intermediary object. However, when the ergonomic guidelines were circulated in the design process, only some of the guidelines were transferred to the design of the sterile processing plant. Based on these findings, recommendations for working with objects in design processes are included. Copyright © 2013 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Variability of Massive Young Stellar Objects in Cygnus-X

NASA Astrophysics Data System (ADS)

Thomas, Nancy H.; Hora, J. L.; Smith, H. A.

2013-01-01

Young stellar objects (YSOs) are stars in the process of formation. Several recent investigations have shown a high rate of photometric variability in YSOs at near- and mid-infrared wavelengths. Theoretical models for the formation of massive stars (1-10 solar masses) remain highly idealized, and little is known about the mechanisms that produce the variability. An ongoing Spitzer Space Telescope program is studying massive star formation in the Cygnus-X region. In conjunction with the Spitzer observations, we have conducted a ground-based near-infrared observing program of the Cygnus-X DR21 field using PAIRITEL, the automated infrared telescope at Whipple Observatory. Using the Stetson index for variability, we identified variable objects and a number of variable YSOs in our time-series PAIRITEL data of DR21. We have searched for periodicity among our variable objects using the Lomb-Scargle algorithm, and identified periodic variable objects with an average period of 8.07 days. Characterization of these variable and periodic objects will help constrain models of star formation present. This work is supported in part by the NSF REU and DOD ASSURE programs under NSF grant no. 0754568 and by the Smithsonian Institution.

Network of TAMCNS: Identifying Influence Regions Within the GCSS-MC Database

DTIC Science & Technology

2017-06-01

relationships between objects and provides tools to quantitatively determine objects whose influence impacts other objects or the system as a whole. This... methodology identifies the most important TAMCN and provides a list of TAMCNs in order of importance. We also analyze the community and core structure of...relationships between objects and provides tools to quantitatively determine objects whose influence impacts other objects or the system as a whole. This

P- T- t constraints on the development of the Doi Inthanon metamorphic core complex domain and implications for the evolution of the western gneiss belt, northern Thailand

NASA Astrophysics Data System (ADS)

Macdonald, A. S.; Barr, S. M.; Miller, B. V.; Reynolds, P. H.; Rhodes, B. P.; Yokart, B.

2010-01-01

The western gneiss belt in northern Thailand is exposed within two overlapping Cenozoic structural domains: the extensional Doi Inthanon metamorphic core complex domain located west of the Chiang Mai basin, and the Mae Ping strike-slip fault domain located west of the Tak batholith. New P- T estimates and U-Pb and 40Ar/ 39Ar age determinations from the Doi Inthanon domain show that the gneiss there records a complex multi-stage history that can be represented by a clockwise P- T- t path. U-Pb zircon and titanite dating of mylonitic calc-silicate gneiss from the Mae Wang area of the complex indicates that the paragneissic sequence experienced high-grade, medium-pressure metamorphism (M1) in the Late Triassic - Early Jurassic (ca. 210 Ma), in good agreement with previously determined zircon ages from the underlying core orthogneiss exposed on Doi Inthanon. Late Cretaceous monazite ages of 84 and 72 Ma reported previously from the core orthogneiss are attributed to a thermal overprint (M2) to upper-amphibolite facies in the sillimanite field. U-Pb zircon and monazite dating of granitic mylonite from the Doi Suthep area of the complex provides an upper age limit of 40 Ma (Late Eocene) for the early stage(s) of development of the actual core complex, by initially ductile, low-angle extensional shearing under lower amphibolite-facies conditions (M3), accompanied by near-isothermal diapiric rise and decompression melting. 40Ar/ 39Ar laserprobe dating of muscovite from both Doi Suthep and Doi Inthanon provided Miocene ages of ca. 26-15 Ma, representing cooling through the ca. 350 °C isotherm and marking late-stage development of the core complex by detachment faulting of the cover rocks and isostatic uplift of the sheared core zone and mantling gneisses in the footwall. Similarities in the thermochronology of high-grade gneisses exposed in the core complex and shear zone domains in the western gneiss belt of northern Thailand (and also in northern Vietnam, Laos, Yunnan

Mechanisms underlying selecting objects for action

PubMed Central

Wulff, Melanie; Laverick, Rosanna; Humphreys, Glyn W.; Wing, Alan M.; Rotshtein, Pia

2015-01-01

We assessed the factors which affect the selection of objects for action, focusing on the role of action knowledge and its modulation by distracters. Fourteen neuropsychological patients and 10 healthy aged-matched controls selected pairs of objects commonly used together among distracters in two contexts: with real objects and with pictures of the same objects presented sequentially on a computer screen. Across both tasks, semantically related distracters led to slower responses and more errors than unrelated distracters and the object actively used for action was selected prior to the object that would be passively held during the action. We identified a sub-group of patients (N = 6) whose accuracy was 2SDs below the controls performances in the real object task. Interestingly, these impaired patients were more affected by the presence of unrelated distracters during both tasks than intact patients and healthy controls. Note that the impaired patients had lesions to left parietal, right anterior temporal and bilateral pre-motor regions. We conclude that: (1) motor procedures guide object selection for action, (2) semantic knowledge affects action-based selection, (3) impaired action decision making is associated with the inability to ignore distracting information and (4) lesions to either the dorsal or ventral visual stream can lead to deficits in making action decisions. Overall, the data indicate that impairments in everyday tasks can be evaluated using a simulated computer task. The implications for rehabilitation are discussed. PMID:25954177

Haptic identification of objects and their depictions.

PubMed

Klatzky, R L; Loomis, J M; Lederman, S J; Wake, H; Fujita, N

1993-08-01

Haptic identification of real objects is superior to that of raised two-dimensional (2-D) depictions. Three explanations of real-object superiority were investigated: contribution of material information, contribution of 3-D shape and size, and greater potential for integration across the fingers. In Experiment 1, subjects, while wearing gloves that gently attenuated material information, haptically identified real objects that provided reduced cues to compliance, mass, and part motion. The gloves permitted exploration with free hand movement, a single outstretched finger, or five outstretched fingers. Performance decreased over these three conditions but was superior to identification of pictures of the same objects in all cases, indicating the contribution of 3-D structure and integration across the fingers. Picture performance was also better with five fingers than with one. In Experiment 2, the subjects wore open-fingered gloves, which provided them with material information. Consequently, the effect of type of exploration was substantially reduced but not eliminated. Material compensates somewhat for limited access to object structure but is not the primary basis for haptic object identification.

Profiling of the Tox21 Chemical Collection for Mitochondrial Function to Identify Compounds that Acutely Decrease Mitochondrial Membrane Potential

PubMed Central

Attene-Ramos, Matias S.; Huang, Ruili; Michael, Sam; Witt, Kristine L.; Richard, Ann; Tice, Raymond R.; Simeonov, Anton; Austin, Christopher P.

2014-01-01

Background: Mitochondrial dysfunction has been implicated in the pathogenesis of a variety of disorders including cancer, diabetes, and neurodegenerative and cardiovascular diseases. Understanding whether different environmental chemicals and druglike molecules impact mitochondrial function represents an initial step in predicting exposure-related toxicity and defining a possible role for such compounds in the onset of various diseases. Objectives: We sought to identify individual chemicals and general structural features associated with changes in mitochondrial membrane potential (MMP). Methods: We used a multiplexed [two end points in one screen; MMP and adenosine triphosphate (ATP) content] quantitative high throughput screening (qHTS) approach combined with informatics tools to screen the Tox21 library of 10,000 compounds (~ 8,300 unique chemicals) at 15 concentrations each in triplicate to identify chemicals and structural features that are associated with changes in MMP in HepG2 cells. Results: Approximately 11% of the compounds (913 unique compounds) decreased MMP after 1 hr of treatment without affecting cell viability (ATP content). In addition, 309 compounds decreased MMP over a concentration range that also produced measurable cytotoxicity [half maximal inhibitory concentration (IC50) in MMP assay/IC50 in viability assay ≤ 3; p < 0.05]. More than 11% of the structural clusters that constitute the Tox21 library (76 of 651 clusters) were significantly enriched for compounds that decreased the MMP. Conclusions: Our multiplexed qHTS approach allowed us to generate a robust and reliable data set to evaluate the ability of thousands of drugs and environmental compounds to decrease MMP. The use of structure-based clustering analysis allowed us to identify molecular features that are likely responsible for the observed activity. Citation: Attene-Ramos MS, Huang R, Michael S, Witt KL, Richard A, Tice RR, Simeonov A, Austin CP, Xia M. 2015. Profiling of the Tox

Use of Self-to-Object and Object-to-Object Spatial Relations in Locomotion

ERIC Educational Resources Information Center

Xiao, Chengli; Mou, Weimin; McNamara, Timothy P.

2009-01-01

In 8 experiments, the authors examined the use of representations of self-to-object or object-to-object spatial relations during locomotion. Participants learned geometrically regular or irregular layouts of objects while standing at the edge or in the middle and then pointed to objects while blindfolded in 3 conditions: before turning (baseline),…

AN OBJECTIVE CLIMATOLOGY OF CAROLINA COASTAL FRONTS

EPA Science Inventory

This study describes a simple objective method to identify cases of coastal frontogenesis offshore of the Carolinas and to characterize the sensible weather associated with frontal passage at measurement sites near the coast. The identification method, based on surface hourly d...

Object detection with a multistatic array using singular value decomposition

DOEpatents

Hallquist, Aaron T.; Chambers, David H.

2014-07-01

A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across a surface and that travels down the surface. The detection system converts the return signals from a time domain to a frequency domain, resulting in frequency return signals. The detection system then performs a singular value decomposition for each frequency to identify singular values for each frequency. The detection system then detects the presence of a subsurface object based on a comparison of the identified singular values to expected singular values when no subsurface object is present.

Learning Objects, Repositories, Sharing and Reusability

ERIC Educational Resources Information Center

Koppi, Tony; Bogle, Lisa; Bogle, Mike

2005-01-01

The online Learning Resource Catalogue (LRC) Project has been part of an international consortium for several years and currently includes 25 institutions worldwide. The LRC Project has evolved for several pragmatic reasons into an academic network whereby members can identify and share reusable learning objects as well as collaborate in a number…

Salient Object Detection via Structured Matrix Decomposition.

PubMed

Peng, Houwen; Li, Bing; Ling, Haibin; Hu, Weiming; Xiong, Weihua; Maybank, Stephen J

2016-05-04

Low-rank recovery models have shown potential for salient object detection, where a matrix is decomposed into a low-rank matrix representing image background and a sparse matrix identifying salient objects. Two deficiencies, however, still exist. First, previous work typically assumes the elements in the sparse matrix are mutually independent, ignoring the spatial and pattern relations of image regions. Second, when the low-rank and sparse matrices are relatively coherent, e.g., when there are similarities between the salient objects and background or when the background is complicated, it is difficult for previous models to disentangle them. To address these problems, we propose a novel structured matrix decomposition model with two structural regularizations: (1) a tree-structured sparsity-inducing regularization that captures the image structure and enforces patches from the same object to have similar saliency values, and (2) a Laplacian regularization that enlarges the gaps between salient objects and the background in feature space. Furthermore, high-level priors are integrated to guide the matrix decomposition and boost the detection. We evaluate our model for salient object detection on five challenging datasets including single object, multiple objects and complex scene images, and show competitive results as compared with 24 state-of-the-art methods in terms of seven performance metrics.

Buried object detection in GPR images

DOEpatents

Paglieroni, David W; Chambers, David H; Bond, Steven W; Beer, W. Reginald

2014-04-29

A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes the return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.

The Automaticity of Affordance of Dangerous Object.

PubMed

Zhao, Liang

2016-11-03

Objects observation automatically elicits the activation of a reach-to-grasp response specifically directed to interact with the object, which is termed affordance. Murphy, van Velzen, and de Fockert (2012) found that only when an irrelevant object receives sufficient attention, it can potentiate an action. However, it remains unclear whether the dangerous object would afford an action when it receives insufficient attention. In this study, we manipulated the perceptual load in a letter identification task. Participants were required to identify a target letter with the right or left hand while ignoring a neutral or dangerous graspable object. The target letter was presented either on its own (low perceptual load), alongside five non-target letters (high load), or alongside eight non-target letters (super high load). Under the low perceptual load, for both neutral and dangerous object, responses were faster when the action afforded by the ignored object was congruent (vs. incongruent) with the current target response (t(27) = 4.44, p < .001; t(27) = 7.99, p < .001, respectively). However, during the high perceptual load, for dangerous object, responses were slower when the action afforded by the ignored object was congruent (vs. incongruent) with the current target response (t(27) = 4.97, p < .001). There was not any effect for both neutral object and dangerous object under super high perceptual load. These results suggest the affordance of dangerous object is also sensitive to the perceptual load. An irrelevant dangerous object can't potentiate an action if it receives insufficient attention.

Designing personal grief rituals: An analysis of symbolic objects and actions.

PubMed

Sas, Corina; Coman, Alina

2016-10-01

Personal grief rituals are beneficial in dealing with complicated grief, but challenging to design, as they require symbolic objects and actions meeting clients' emotional needs. The authors reported interviews with 10 therapists with expertise in both grief therapy and grief rituals. Findings indicate three types of rituals supporting honoring, letting go, and self transformation, with the latter being particularly complex. Outcomes also point to a taxonomy of ritual objects for framing and remembering ritual experience, and for capturing and processing grief. Besides symbolic possessions, the authors identified other types of ritual objects including transformational and future-oriented ones. Symbolic actions include creative craft of ritual objects, respectful handling, disposal, and symbolic play. They conclude with theoretical implications of these findings, and a reflection on their value for tailored, creative co-design of grief rituals. In particular, several implications for designing grief rituals were identified that include accounting for the client's need, selecting (or creating) the most appropriate objects and actions from the identified types, integrating principles of both grief and art/drama therapy, exploring clients' affinity for the ancient elements as medium of disposal in letting go rituals, and the value of technology for recording and reflecting on ritual experience.

Floor Sensing System Using Laser Reflectivity for Localizing Everyday Objects and Robot

PubMed Central

Pyo, Yoonseok; Hasegawa, Tsutomu; Tsuji, Tokuo; Kurazume, Ryo; Morooka, Ken'ichi

2014-01-01

This paper describes a new method of measuring the position of everyday objects and a robot on the floor using distance and reflectance acquired by laser range finder (LRF). The information obtained by this method is important for a service robot working in a human daily life environment. Our method uses only one LRF together with a mirror installed on the wall. Moreover, since the area of sensing is limited to a LRF scanning plane parallel to the floor and just a few centimeters above the floor, the scanning covers the whole room with minimal invasion of privacy of a resident, and occlusion problem is mitigated by using mirror. We use the reflection intensity and position information obtained from the target surface. Although it is not possible to identify all objects by additionally using reflection values, it would be easier to identify unknown objects if we can eliminate easily identifiable objects by reflectance. In addition, we propose a method for measuring the robot's pose using the tag which has the encoded reflection pattern optically identified by the LRF. Our experimental results validate the effectiveness of the proposed method. PMID:24763253

Memory Load Affects Object Individuation in 18-Month-Old Infants

ERIC Educational Resources Information Center

Zosh, Jennifer M.; Feigenson, Lisa

2012-01-01

Accurate representation of a changing environment requires individuation--the ability to determine how many numerically distinct objects are present in a scene. Much research has characterized early individuation abilities by identifying which object features infants can use to individuate throughout development. However, despite the fact that…

An international survey to identify the intrinsic and extrinsic factors of research studies most likely to change orthopaedic practice.

PubMed

Thornley, P; de Sa, D; Evaniew, N; Farrokhyar, F; Bhandari, M; Ghert, M

2016-04-01

Evidence -based medicine (EBM) is designed to inform clinical decision-making within all medical specialties, including orthopaedic surgery. We recently published a pilot survey of the Canadian Orthopaedic Association (COA) membership and demonstrated that the adoption of EBM principles is variable among Canadian orthopaedic surgeons. The objective of this study was to conduct a broader international survey of orthopaedic surgeons to identify characteristics of research studies perceived as being most influential in informing clinical decision-making. A 29-question electronic survey was distributed to the readership of an established orthopaedic journal with international readership. The survey aimed to analyse the influence of both extrinsic (journal quality, investigator profiles, etc.) and intrinsic characteristics (study design, sample size, etc.) of research studies in relation to their influence on practice patterns. A total of 353 surgeons completed the survey. Surgeons achieved consensus on the 'importance' of three key designs on their practices: randomised controlled trials (94%), meta-analyses (75%) and systematic reviews (66%). The vast majority of respondents support the use of current evidence over historical clinical training; however subjective factors such as journal reputation (72%) and investigator profile (68%) continue to influence clinical decision-making strongly. Although intrinsic factors such as study design and sample size have some influence on clinical decision-making, surgeon respondents are equally influenced by extrinsic factors such as investigator reputation and perceived journal quality.Cite this article: Dr M. Ghert. An international survey to identify the intrinsic and extrinsic factors of research studies most likely to change orthopaedic practice. Bone Joint Res 2016;5:130-136. DOI: 10.1302/2046-3758.54.2000578. © 2016 Ghert et al.

41 CFR 102-75.660 - What happens if DOI does not approve any applications or does not submit an assignment...

Code of Federal Regulations, 2010 CFR

2010-07-01

... not approve any applications or does not submit an assignment recommendation? 102-75.660 Section 102-75.660 Public Contracts and Property Management Federal Property Management Regulations System... approve any applications or does not submit an assignment recommendation? If DOI does not approve any...

Object Extraction in Cluttered Environments via a P300-Based IFCE

PubMed Central

He, Huidong; Xian, Bin; Zeng, Ming; Zhou, Huihui; Niu, Linwei; Chen, Genshe

2017-01-01

One of the fundamental issues for robot navigation is to extract an object of interest from an image. The biggest challenges for extracting objects of interest are how to use a machine to model the objects in which a human is interested and extract them quickly and reliably under varying illumination conditions. This article develops a novel method for segmenting an object of interest in a cluttered environment by combining a P300-based brain computer interface (BCI) and an improved fuzzy color extractor (IFCE). The induced P300 potential identifies the corresponding region of interest and obtains the target of interest for the IFCE. The classification results not only represent the human mind but also deliver the associated seed pixel and fuzzy parameters to extract the specific objects in which the human is interested. Then, the IFCE is used to extract the corresponding objects. The results show that the IFCE delivers better performance than the BP network or the traditional FCE. The use of a P300-based IFCE provides a reliable solution for assisting a computer in identifying an object of interest within images taken under varying illumination intensities. PMID:28740505

Road detection and buried object detection in elevated EO/IR imagery

NASA Astrophysics Data System (ADS)

Kennedy, Levi; Kolba, Mark P.; Walters, Joshua R.

2012-06-01

To assist the warfighter in visually identifying potentially dangerous roadside objects, the U.S. Army RDECOM CERDEC Night Vision and Electronic Sensors Directorate (NVESD) has developed an elevated video sensor system testbed for data collection. This system provides color and mid-wave infrared (MWIR) imagery. Signal Innovations Group (SIG) has developed an automated processing capability that detects the road within the sensor field of view and identifies potentially threatening buried objects within the detected road. The road detection algorithm leverages system metadata to project the collected imagery onto a flat ground plane, allowing for more accurate detection of the road as well as the direct specification of realistic physical constraints in the shape of the detected road. Once the road has been detected in an image frame, a buried object detection algorithm is applied to search for threatening objects within the detected road space. The buried object detection algorithm leverages textural and pixel intensity-based features to detect potential anomalies and then classifies them as threatening or non-threatening objects. Both the road detection and the buried object detection algorithms have been developed to facilitate their implementation in real-time in the NVESD system.

Kyiv Small Rivers in Metropolis Water Objects System

NASA Astrophysics Data System (ADS)

Krelshteyn, P.; Dubnytska, M.

2017-12-01

The article answers the question, what really are the small underground rivers with artificial watercourses: water bodies or city engineering infrastructure objects? The place of such rivers in metropolis water objects system is identified. The ecological state and the degree of urbanization of small rivers, as well as the dynamics of change in these indicators are analysed on the Kiev city example with the help of water objects cadastre. It was found that the registration of small rivers in Kyiv city is not conducted, and the summary information on such water objects is absent and is not taken into account when making managerial decisions at the urban level. To solve this problem, we propose to create some water bodies accounting system (water cadastre).

Model-based occluded object recognition using Petri nets

NASA Astrophysics Data System (ADS)

Zhou, Chuan; Hura, Gurdeep S.

1998-09-01

This paper discusses the use of Petri nets to model the process of the object matching between an image and a model under different 2D geometric transformations. This transformation finds its applications in sensor-based robot control, flexible manufacturing system and industrial inspection, etc. A description approach for object structure is presented by its topological structure relation called Point-Line Relation Structure (PLRS). It has been shown how Petri nets can be used to model the matching process, and an optimal or near optimal matching can be obtained by tracking the reachability graph of the net. The experiment result shows that object can be successfully identified and located under 2D transformation such as translations, rotations, scale changes and distortions due to object occluded partially.

A memory span of one? Object identification in 6.5-month-old infants.

PubMed

Káldy, Zsuzsa; Leslie, Alan M

2005-09-01

Infants' abilities to identify objects based on their perceptual features develop gradually during the first year and possibly beyond. Earlier we reported [Káldy, Z., & Leslie, A. M. (2003). Identification of objects in 9-month-old infants: Integrating 'what' and 'where' information. Developmental Science, 6, 360-373] that infants at 9 months of age are able to use shape information to identify two objects and follow their spatiotemporal trajectories behind occlusion. On the other hand, another recent study suggests that infants at 4-5 months of age cannot identify objects by features and bind them to locations [Mareschal, D., & Johnson, M. H. (2003). The "what" and "where" of object representations in infancy. Cognition, 88, 259-276]. In the current study, we investigated the developmental steps between these two benchmark ages by testing 6.5-month-old infants. Experiment 1 and 2 adapted the paradigm used in our previous studies with 9-month-olds that involves two objects hidden sequentially behind separate occluders. This technique allows us to address object identification and to examine whether only one or both object identities are being tracked. Results of experiment 1 showed that 6.5-month-old infants could identify at least one of two objects based on shape and experiment 2 found that this ability holds for only one, the last object hidden. We propose that at this age, infants' working memory capacity is limited to one occluded object if there is a second intervening hiding. If their attention is distracted by an intervening object during the memory maintenance period, the memory of the first object identity appears to be lost. Results of experiment 3 supported this hypothesis with a simpler one-screen setup. Finally, results of experiment 4 show that temporal decay of the memory trace (without an intervening hiding) by itself cannot explain the observed pattern of results. Taken together, our findings suggest that at six months of age infants can store

Object tracking using multiple camera video streams

NASA Astrophysics Data System (ADS)

Mehrubeoglu, Mehrube; Rojas, Diego; McLauchlan, Lifford

2010-05-01

Two synchronized cameras are utilized to obtain independent video streams to detect moving objects from two different viewing angles. The video frames are directly correlated in time. Moving objects in image frames from the two cameras are identified and tagged for tracking. One advantage of such a system involves overcoming effects of occlusions that could result in an object in partial or full view in one camera, when the same object is fully visible in another camera. Object registration is achieved by determining the location of common features in the moving object across simultaneous frames. Perspective differences are adjusted. Combining information from images from multiple cameras increases robustness of the tracking process. Motion tracking is achieved by determining anomalies caused by the objects' movement across frames in time in each and the combined video information. The path of each object is determined heuristically. Accuracy of detection is dependent on the speed of the object as well as variations in direction of motion. Fast cameras increase accuracy but limit the speed and complexity of the algorithm. Such an imaging system has applications in traffic analysis, surveillance and security, as well as object modeling from multi-view images. The system can easily be expanded by increasing the number of cameras such that there is an overlap between the scenes from at least two cameras in proximity. An object can then be tracked long distances or across multiple cameras continuously, applicable, for example, in wireless sensor networks for surveillance or navigation.

Using FMRI brain activation to identify cognitive states associated with perception of tools and dwellings.

PubMed

Shinkareva, Svetlana V; Mason, Robert A; Malave, Vicente L; Wang, Wei; Mitchell, Tom M; Just, Marcel Adam

2008-01-02

Previous studies have succeeded in identifying the cognitive state corresponding to the perception of a set of depicted categories, such as tools, by analyzing the accompanying pattern of brain activity, measured with fMRI. The current research focused on identifying the cognitive state associated with a 4s viewing of an individual line drawing (1 of 10 familiar objects, 5 tools and 5 dwellings, such as a hammer or a castle). Here we demonstrate the ability to reliably (1) identify which of the 10 drawings a participant was viewing, based on that participant's characteristic whole-brain neural activation patterns, excluding visual areas; (2) identify the category of the object with even higher accuracy, based on that participant's activation; and (3) identify, for the first time, both individual objects and the category of the object the participant was viewing, based only on other participants' activation patterns. The voxels important for category identification were located similarly across participants, and distributed throughout the cortex, focused in ventral temporal perceptual areas but also including more frontal association areas (and somewhat left-lateralized). These findings indicate the presence of stable, distributed, communal, and identifiable neural states corresponding to object concepts.

Abstract Representations of Object-Directed Action in the Left Inferior Parietal Lobule.

PubMed

Chen, Quanjing; Garcea, Frank E; Jacobs, Robert A; Mahon, Bradford Z

2018-06-01

Prior neuroimaging and neuropsychological research indicates that the left inferior parietal lobule in the human brain is a critical substrate for representing object manipulation knowledge. In the present functional MRI study we used multivoxel pattern analyses to test whether action similarity among objects can be decoded in the inferior parietal lobule independent of the task applied to objects (identification or pantomime) and stimulus format in which stimuli are presented (pictures or printed words). Participants pantomimed the use of objects, cued by printed words, or identified pictures of objects. Classifiers were trained and tested across task (e.g., training data: pantomime; testing data: identification), stimulus format (e.g., training data: word format; testing format: picture) and specific objects (e.g., training data: scissors vs. corkscrew; testing data: pliers vs. screwdriver). The only brain region in which action relations among objects could be decoded across task, stimulus format and objects was the inferior parietal lobule. By contrast, medial aspects of the ventral surface of the left temporal lobe represented object function, albeit not at the same level of abstractness as actions in the inferior parietal lobule. These results suggest compulsory access to abstract action information in the inferior parietal lobe even when simply identifying objects.

Neural basis for dynamic updating of object representation in visual working memory.

PubMed

Takahama, Sachiko; Miyauchi, Satoru; Saiki, Jun

2010-02-15

In real world, objects have multiple features and change dynamically. Thus, object representations must satisfy dynamic updating and feature binding. Previous studies have investigated the neural activity of dynamic updating or feature binding alone, but not both simultaneously. We investigated the neural basis of feature-bound object representation in a dynamically updating situation by conducting a multiple object permanence tracking task, which required observers to simultaneously process both the maintenance and dynamic updating of feature-bound objects. Using an event-related design, we separated activities during memory maintenance and change detection. In the search for regions showing selective activation in dynamic updating of feature-bound objects, we identified a network during memory maintenance that was comprised of the inferior precentral sulcus, superior parietal lobule, and middle frontal gyrus. In the change detection period, various prefrontal regions, including the anterior prefrontal cortex, were activated. In updating object representation of dynamically moving objects, the inferior precentral sulcus closely cooperates with a so-called "frontoparietal network", and subregions of the frontoparietal network can be decomposed into those sensitive to spatial updating and feature binding. The anterior prefrontal cortex identifies changes in object representation by comparing memory and perceptual representations rather than maintaining object representations per se, as previously suggested. Copyright 2009 Elsevier Inc. All rights reserved.

Nine-month-old infants generalize object labels, but not object preferences across individuals.

PubMed

Henderson, Annette M E; Woodward, Amanda L

2012-09-01

As with all culturally relevant human behaviours, words are meaningful because they are shared by the members of a community. This research investigates whether 9-month-old infants understand this fundamental fact about language. Experiment 1 examined whether infants who are trained on, and subsequently habituated to, a new word-referent link expect the link to be consistent across a second speaker. Experiment 2 examined whether 9-month-old infants distinguish between behaviours that are shared across individuals (i.e. words) from those that are not (i.e. object preferences). The present findings indicate that infants as young as 9 months of age expect new word-referent links, but not object preferences, to be consistent across individuals. Thus, by 9 months, infants have identified at least one of the aspects of human behaviour that is shared across individuals within a community. The implications for children's acquisition of language and culture are discussed. © 2012 Blackwell Publishing Ltd.

Nine-month-old infants generalize object labels, but not object preferences across individuals

PubMed Central

Woodward, Amanda L.

2012-01-01

As with all culturally relevant human behaviours, words are meaningful because they are shared by the members of a community. This research investigates whether 9-month-old infants understand this fundamental fact about language. Experiment 1 examined whether infants who are trained on, and subsequently habituated to, a new word-referent link expect the link to be consistent across a second speaker. Experiment 2 examined whether 9-month-old infants distinguish between behaviours that are shared across individuals (i.e., words) from those that are not (i.e., object preferences). The present findings indicate that infants as young as 9 months of age expect new word-referent links, but not object preferences, to be consistent across individuals. Thus, by 9 months, infants have identified at least one of the aspects of human behaviour that is shared across individuals within a community. The implications for children’s acquisition of language and culture are discussed. PMID:22925512

Environmental Management System Objectives & Targets Results Summary - FY 2015.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vetter, Douglas W.

2016-02-01

Sandia National Laboratories (SNL) Environmental Management System is the integrated approach for members of the workforce to identify and manage environmental risks. Each Fiscal Year (FY) SNL performs an analysis to identify environmental aspects, and the environmental programs associated with them are charged with the task of routinely monitoring and measuring the objectives and targets that are established to mitigate potential impacts of SNL's operations on the environment. An annual summary of the results achieved towards meeting established Sandia Corporation and SNL Site-specific objectives and targets provides a connection to, and rational for, annually revised environmental aspects. The purpose ofmore » this document is to summarize the results achieved and documented in FY 2015.« less

Serotonin (5-HT)2A/2C receptor agonist (2,5-dimethoxy-4-idophenyl)-2-aminopropane hydrochloride (DOI) improves voiding efficiency in the diabetic rat.

PubMed

Tu, Hongjian; Cao, Nailong; Gu, Baojun; Si, Jiemin; Chen, Zhong; Andersson, Karl-Erik

2015-07-01

To examine the effects of the serotonin (5-HT)2A/2C receptor agonist (2,5-dimethoxy-4-idophenyl)-2-aminopropane hydrochloride (DOI) on micturition in rats with diabetes mellitus (DM). Female Sprague-Dawley rats (n = 16) were divided into two groups: rats with Type 1 DM and age-matched control rats. DM was induced by i.p. injection of streptozotocin (65 mg/kg) and detailed cystometrogram (CMG) studies were performed 8 weeks post-injection in all rats under urethane anaesthesia. The selective 5-HT2A antagonist ketanserin was administered after each DOI dose-response curve was plotted. All drugs were administered i.v. Compared with controls, comprehensive urodynamic studies showed that DM rats had a higher bladder capacity and post-void residual urine volume (PVR), and a markedly lower voiding efficiency. In DM rats, DOI (0.01-0.3 mg/kg) induced significant dose-dependent increases in micturition volume and reductions in PVR, resulting in greater voiding efficiency. CMG measurements showed a dose-dependent increase in high-frequency oscillation (HFO) activity, evidenced by an increased duration of HFOs per voiding. This correlated with the improved voiding efficiency. Ketanserin (0.1 mg/kg) partially or completely reversed the DOI-induced changes. The HFOs observed in the present study seem to correlate with external urethral sphincter bursting activity during voiding. Bladder voiding efficiency was reduced in DM rats. The 5-HT2A receptor agonist can enhance HFO activity and improves voiding efficiency, and so may represent a new strategy to improve voiding efficiency after DM in experimental studies. © 2014 The Authors BJU International © 2014 BJU International Published by John Wiley & Sons Ltd.

Learning Objects as Tools for Teaching Information Literacy Online: A Survey of Librarian Usage

ERIC Educational Resources Information Center

Mestre, Lori S.; Baures, Lisa; Niedbala, Mona; Bishop, Corinne; Cantrell, Sarah; Perez, Alice; Silfen, Kate

2011-01-01

Based on information gathered from two discussion sessions moderated by members of the Education and Behavioral Sciences Section's Online Learning Research Committee a survey was conducted to identify how librarians use course/learning management systems and learning objects to deliver instruction. Objectives of the study were to identify the…

Implemented or Not Implemented? Process Evaluation of the School-Based Obesity Prevention Program DOiT and Associations with Program Effectiveness

ERIC Educational Resources Information Center

van Nassau, Femke; Singh, Amika S.; Hoekstra, Trynke; van Mechelen, Willem; Brug, Johannes; Chinapaw, Mai J. M.

2016-01-01

This study investigates if and to what extent the Dutch Obesity Intervention in Teenagers (DOiT) program was implemented as intended and how this affected program effectiveness. We collected data at 20 prevocational education schools in the Netherlands. We assessed seven process indicators: recruitment, reach, dosage, fidelity, satisfaction,…

The Past, Present and Future of the Compact Disc, Multimedia and the Industry: An Interview with Sony's Dr. Toshi Doi.

ERIC Educational Resources Information Center

Herther, Nancy

1992-01-01

This interview with Dr. Toshi Doi, director of the Sony Corporation, covers his work at Sony, the multimedia industry, industry cooperation, Sony compact disc products and formats, multimedia standards and pricing, multimedia formats, and the future of the industry. A diagram of computer companies and corresponding multimedia platforms is…

Recognition of 3-D Scene with Partially Occluded Objects

NASA Astrophysics Data System (ADS)

Lu, Siwei; Wong, Andrew K. C...

1987-03-01

This paper presents a robot vision system which is capable of recognizing objects in a 3-D scene and interpreting their spatial relation even though some objects in the scene may be partially occluded by other objects. An algorithm is developed to transform the geometric information from the range data into an attributed hypergraph representation (AHR). A hypergraph monomorphism algorithm is then used to compare the AHR of objects in the scene with a set of complete AHR's of prototypes. The capability of identifying connected components and interpreting various types of edges in the 3-D scene enables us to distinguish objects which are partially blocking each other in the scene. Using structural information stored in the primitive area graph, a heuristic hypergraph monomorphism algorithm provides an effective way for recognizing, locating, and interpreting partially occluded objects in the range image.

Monitoring Object Library Usage and Changes

NASA Technical Reports Server (NTRS)

Owen, R. K.; Craw, James M. (Technical Monitor)

1995-01-01

The NASA Ames Numerical Aerodynamic Simulation program Aeronautics Consolidated Supercomputing Facility (NAS/ACSF) supercomputing center services over 1600 users, and has numerous analysts with root access. Several tools have been developed to monitor object library usage and changes. Some of the tools do "noninvasive" monitoring and other tools implement run-time logging even for object-only libraries. The run-time logging identifies who, when, and what is being used. The benefits are that real usage can be measured, unused libraries can be discontinued, training and optimization efforts can be focused at those numerical methods that are actually used. An overview of the tools will be given and the results will be discussed.

Secondary school biology teaching, 1983--2004: Objectives as stated in periodical literature

NASA Astrophysics Data System (ADS)

Russell, James W., Sr.

Purpose of the study. The major purpose of this study was to identify and to classify objectives for teaching biology in secondary school in the United States during the period 1983-2004. These objectives were identified by objective statements in articles from selected professional periodicals. Procedure. The 1983-2004 period was divided into four subperiods on the basis of major historical events. Selected professional periodicals were searched for statements of objectives of secondary school biology teaching. These statements were catalogued into Knowledge, Process, Product, Attitude and Interest, or Cultural Awareness categories. The resulting data were classified within and across the four subperiods according to frequency of occurrence, category, authorship, and year. Findings. The major findings of this investigation included the following: (1) Authorships in Higher Education produced the most articles and the most statements in each subperiod. Miscellaneous authors produced the least articles and statements. (2) Statements in the Attitude and Interest category were the most frequent in the four subperiods. (3) The "most important" objectives for secondary school biology teaching were Presents major facts, principles, or fundamentals (from the Knowledge category), Expresses scientific attitudes and appreciation, Identifies the nature of science and scientists, and Identifies scientific interest and career development (from the Attitude and Interest category), and Develops scientific method of thinking (from the Process category). Conclusions. Based on the findings of this investigation, the following conclusions were made: (1) The objectives for teaching secondary school biology were influenced by historical events, especially the publication of A Nation at Risk: The Imperative for Educational Reform in 1983, America 2000 in 1988, Goals 2000 in 1994, No Child Left Behind in 2000. The rapid growth and expansion of technology and the World Wide Web during the

Towards an Artificial Space Object Taxonomy

NASA Astrophysics Data System (ADS)

Wilkins, M.; Schumacher, P.; Jah, M.; Pfeffer, A.

2013-09-01

Object recognition is the first step in positively identifying a resident space object (RSO), i.e. assigning an RSO to a category such as GPS satellite or space debris. Object identification is the process of deciding that two RSOs are in fact one and the same. Provided we have appropriately defined a satellite taxonomy that allows us to place a given RSO into a particular class of object without any ambiguity, one can assess the probability of assignment to a particular class by determining how well the object satisfies the unique criteria of belonging to that class. Ultimately, tree-based taxonomies delineate unique signatures by defining the minimum amount of information required to positively identify a RSO. Therefore, taxonomic trees can be used to depict hypotheses in a Bayesian object recognition and identification process. This work describes a new RSO taxonomy along with specific reasoning behind the choice of groupings. An alternative taxonomy was recently presented at the Sixth Conference on Space Debris in Darmstadt, Germany. [1] The best example of a taxonomy that enjoys almost universal scientific acceptance is the classical Linnaean biological taxonomy. A strength of Linnaean taxonomy is that it can be used to organize the different kinds of living organisms, simply and practically. Every species can be given a unique name. This uniqueness and stability are a result of the acceptance by biologists specializing in taxonomy, not merely of the binomial names themselves. Fundamentally, the taxonomy is governed by rules for the use of these names, and these are laid down in formal Nomenclature Codes. We seek to provide a similar formal nomenclature system for RSOs through a defined tree-based taxonomy structure. Each categorization, beginning with the most general or inclusive, at any level is called a taxon. Taxon names are defined by a type, which can be a specimen or a taxon of lower rank, and a diagnosis, a statement intended to supply characters that

Scout: orbit analysis and hazard assessment for NEOCP objects

NASA Astrophysics Data System (ADS)

Farnocchia, Davide; Chesley, Steven R.; Chamberlin, Alan B.

2016-10-01

It typically takes a few days for a newly discovered asteroid to be officially recognized as a real object. During this time, the tentative discovery is published on the Minor Planet Center's Near-Earth Object Confirmation Page (NEOCP) until additional observations confirm that the object is a real asteroid rather than an observational artifact or an artificial object. Also, NEOCP objects could have a limited observability window and yet be scientifically interesting, e.g., radar and lightcurve targets, mini-moons (temporary Earth captures), mission accessible targets, close approachers or even impactors. For instance, the only two asteroids discovered before an impact, 2008 TC3 and 2014 AA, both reached the Earth less than a day after discovery. For these reasons we developed Scout, an automated system that provides an orbital and hazard assessment for NEOCP objects within minutes after the observations are available. Scout's rapid analysis increases the chances of securing the trajectory of interesting NEOCP objects before the ephemeris uncertainty grows too large or the observing geometry becomes unfavorable. The generally short observation arcs, perhaps only a few hours or even less, lead severe degeneracies in the orbit estimation process. To overcome these degeneracies Scout relies on systematic ranging, a technique that derives possible orbits by scanning a grid in the poorly constrained space of topocentric range and range rate, while the plane-of-sky position and motion are directly tied to the recorded observations. This scan allows us to derive a distribution of the possible orbits and in turn identify the NEOCP objects of most interest to prioritize followup efforts. In particular, Scout ranks objects according to the likelihood of an impact, estimates the close approach distance, the Earth-relative minimum orbit intersection distance and v-infinity, and computes scores to identify objects more likely to be an NEO, a km-sized NEO, a Potentially

Hallucinogenic 5-HT2AR agonists LSD and DOI enhance dopamine D2R protomer recognition and signaling of D2-5-HT2A heteroreceptor complexes.

PubMed

Borroto-Escuela, Dasiel O; Romero-Fernandez, Wilber; Narvaez, Manuel; Oflijan, Julia; Agnati, Luigi F; Fuxe, Kjell

2014-01-03

Dopamine D2LR-serotonin 5-HT2AR heteromers were demonstrated in HEK293 cells after cotransfection of the two receptors and shown to have bidirectional receptor-receptor interactions. In the current study the existence of D2L-5-HT2A heteroreceptor complexes was demonstrated also in discrete regions of the ventral and dorsal striatum with in situ proximity ligation assays (PLA). The hallucinogenic 5-HT2AR agonists LSD and DOI but not the standard 5-HT2AR agonist TCB2 and 5-HT significantly increased the density of D2like antagonist (3)H-raclopride binding sites and significantly reduced the pKiH values of the high affinity D2R agonist binding sites in (3)H-raclopride/DA competition experiments. Similar results were obtained in HEK293 cells and in ventral striatum. The effects of the hallucinogenic 5-HT2AR agonists on D2R density and affinity were blocked by the 5-HT2A antagonist ketanserin. In a forskolin-induced CRE-luciferase reporter gene assay using cotransfected but not D2R singly transfected HEK293 cells DOI and LSD but not TCB2 significantly enhanced the D2LR agonist quinpirole induced inhibition of CRE-luciferase activity. Haloperidol blocked the effects of both quinpirole alone and the enhancing actions of DOI and LSD while ketanserin only blocked the enhancing actions of DOI and LSD. The mechanism for the allosteric enhancement of the D2R protomer recognition and signalling observed is likely mediated by a biased agonist action of the hallucinogenic 5-HT2AR agonists at the orthosteric site of the 5-HT2AR protomer. This mechanism may contribute to the psychotic actions of LSD and DOI and the D2-5-HT2A heteroreceptor complex may thus be a target for the psychotic actions of hallunicogenic 5-HT2A agonists. Copyright © 2013 Elsevier Inc. All rights reserved.

Key Objectives Bank: Year 9. Key Stage 3: National Strategy.

ERIC Educational Resources Information Center

Department for Education and Skills, London (England).

In each sub-section of the "Framework for Teaching English: Years 7, 8 and 9," certain key objectives are identified in boldface print. These objectives are key because they signify skills or understanding which are crucial to pupils' language development. They are challenging for the age group and are important markers of progress. This…

Identification of Object Dynamics Using Hand Worn Motion and Force Sensors

PubMed Central

Kortier, Henk G.; Schepers, H. Martin; Veltink, Peter H.

2016-01-01

Emerging microelectromechanical system (MEMS)-based sensors become much more applicable for on-body measurement purposes lately. Especially, the development of a finger tip-sized tri-axial force sensor gives the opportunity to measure interaction forces between the human hand and environmental objects. We have developed a new prototype device that allows simultaneous 3D force and movement measurements at the finger and thumb tips. The combination of interaction forces and movements makes it possible to identify the dynamical characteristics of the object being handled by the hand. With this device attached to the hand, a subject manipulated mass and spring objects under varying conditions. We were able to identify and estimate the weight of two physical mass objects (0.44 kg: 29.3%±18.9% and 0.28 kg: 19.7%±10.6%) and the spring constant of a physical spring object (16.3%±12.6%). The system is a first attempt to quantify the interactions of the hand with the environment and has many potential applications in rehabilitation, ergonomics and sports. PMID:27898040

Object-oriented design tools for supramolecular devices and biomedical nanotechnology.

PubMed

Lee, Stephen C; Bhalerao, Khaustaub; Ferrari, Mauro

2004-05-01

Nanotechnology provides multifunctional agents for in vivo use that increasingly blur the distinction between pharmaceuticals and medical devices. Realization of such therapeutic nanodevices requires multidisciplinary effort that is difficult for individual device developers to sustain, and identification of appropriate collaborations outside ones own field can itself be challenging. Further, as in vivo nanodevices become increasingly complex, their design will increasingly demand systems level thinking. System engineering tools such as object-oriented analysis, object-oriented design (OOA/D) and unified modeling language (UML) are applicable to nanodevices built from biological components, help logically manage the knowledge needed to design them, and help identify useful collaborative relationships for device designers. We demonstrate the utility of these systems engineering tools by reverse engineering an existing molecular device (the bacmid molecular cloning system) using them, and illustrate how object-oriented approaches identify fungible components (objects) in nanodevices in a way that facilitates design of families of related devices, rather than single inventions. We also explore the utility of object-oriented approaches for design of another class of therapeutic nanodevices, vaccines. While they are useful for design of current nanodevices, the power of systems design tools for biomedical nanotechnology will become increasingly apparent as the complexity and sophistication of in vivo nanosystems increases. The nested, hierarchical nature of object-oriented approaches allows treatment of devices as objects in higher-order structures, and so will facilitate concatenation of multiple devices into higher-order, higher-function nanosystems.

Automatic Recognition of Object Names in Literature

NASA Astrophysics Data System (ADS)

Bonnin, C.; Lesteven, S.; Derriere, S.; Oberto, A.

2008-08-01

SIMBAD is a database of astronomical objects that provides (among other things) their bibliographic references in a large number of journals. Currently, these references have to be entered manually by librarians who read each paper. To cope with the increasing number of papers, CDS develops a tool to assist the librarians in their work, taking advantage of the Dictionary of Nomenclature of Celestial Objects, which keeps track of object acronyms and of their origin. The program searches for object names directly in PDF documents by comparing the words with all the formats stored in the Dictionary of Nomenclature. It also searches for variable star names based on constellation names and for a large list of usual names such as Aldebaran or the Crab. Object names found in the documents often correspond to several astronomical objects. The system retrieves all possible matches, displays them with their object type given by SIMBAD, and lets the librarian make the final choice. The bibliographic reference can then be automatically added to the object identifiers in the database. Besides, the systematic usage of the Dictionary of Nomenclature, which is updated manually, permitted to automatically check it and to detect errors and inconsistencies. Last but not least, the program collects some additional information such as the position of the object names in the document (in the title, subtitle, abstract, table, figure caption...) and their number of occurrences. In the future, this will permit to calculate the 'weight' of an object in a reference and to provide SIMBAD users with an important new information, which will help them to find the most relevant papers in the object reference list.

The role of connectedness in haptic object perception.

PubMed

Plaisier, Myrthe A; van Polanen, Vonne; Kappers, Astrid M L

2017-03-02

We can efficiently detect whether there is a rough object among a set of smooth objects using our sense of touch. We can also quickly determine the number of rough objects in our hand. In this study, we investigated whether the perceptual processing of rough and smooth objects is influenced if these objects are connected. In Experiment 1, participants were asked to identify whether there were exactly two rough target spheres among smooth distractor spheres, while we recorded their response times. The spheres were connected to form pairs: rough spheres were paired together and smooth spheres were paired together ('within pairs arrangement'), or a rough and a smooth sphere were connected ('between pairs arrangement'). Participants responded faster when the spheres in a pair were identical. In Experiment 2, we found that the advantage for within pairs arrangements was not driven by feature saliency. Overall our results show that haptic information is processed faster when targets were connected together compared to when targets were connected to distractors.

Resolving human object recognition in space and time

PubMed Central

Cichy, Radoslaw Martin; Pantazis, Dimitrios; Oliva, Aude

2014-01-01

A comprehensive picture of object processing in the human brain requires combining both spatial and temporal information about brain activity. Here, we acquired human magnetoencephalography (MEG) and functional magnetic resonance imaging (fMRI) responses to 92 object images. Multivariate pattern classification applied to MEG revealed the time course of object processing: whereas individual images were discriminated by visual representations early, ordinate and superordinate category levels emerged relatively later. Using representational similarity analysis, we combine human fMRI and MEG to show content-specific correspondence between early MEG responses and primary visual cortex (V1), and later MEG responses and inferior temporal (IT) cortex. We identified transient and persistent neural activities during object processing, with sources in V1 and IT., Finally, human MEG signals were correlated to single-unit responses in monkey IT. Together, our findings provide an integrated space- and time-resolved view of human object categorization during the first few hundred milliseconds of vision. PMID:24464044

Scientists' Prioritization of Communication Objectives for Public Engagement.

PubMed

Dudo, Anthony; Besley, John C

2016-01-01

Amid calls from scientific leaders for their colleagues to become more effective public communicators, this study examines the objectives that scientists' report drive their public engagement behaviors. We explore how scientists evaluate five specific communication objectives, which include informing the public about science, exciting the public about science, strengthening the public's trust in science, tailoring messages about science, and defending science from misinformation. We use insights from extant research, the theory of planned behavior, and procedural justice theory to identify likely predictors of scientists' views about these communication objectives. Results show that scientists most prioritize communication designed to defend science from misinformation and educate the public about science, and least prioritize communication that seeks to build trust and establish resonance with the public. Regression analyses reveal factors associated with scientists who prioritize each of the five specific communication objectives. Our findings highlight the need for communication trainers to help scientists select specific communication objectives for particular contexts and audiences.

Scientists’ Prioritization of Communication Objectives for Public Engagement

PubMed Central

2016-01-01

Amid calls from scientific leaders for their colleagues to become more effective public communicators, this study examines the objectives that scientists’ report drive their public engagement behaviors. We explore how scientists evaluate five specific communication objectives, which include informing the public about science, exciting the public about science, strengthening the public’s trust in science, tailoring messages about science, and defending science from misinformation. We use insights from extant research, the theory of planned behavior, and procedural justice theory to identify likely predictors of scientists' views about these communication objectives. Results show that scientists most prioritize communication designed to defend science from misinformation and educate the public about science, and least prioritize communication that seeks to build trust and establish resonance with the public. Regression analyses reveal factors associated with scientists who prioritize each of the five specific communication objectives. Our findings highlight the need for communication trainers to help scientists select specific communication objectives for particular contexts and audiences. PMID:26913869

Object-graphs for context-aware visual category discovery.

PubMed

Lee, Yong Jae; Grauman, Kristen

2012-02-01

How can knowing about some categories help us to discover new ones in unlabeled images? Unsupervised visual category discovery is useful to mine for recurring objects without human supervision, but existing methods assume no prior information and thus tend to perform poorly for cluttered scenes with multiple objects. We propose to leverage knowledge about previously learned categories to enable more accurate discovery, and address challenges in estimating their familiarity in unsegmented, unlabeled images. We introduce two variants of a novel object-graph descriptor to encode the 2D and 3D spatial layout of object-level co-occurrence patterns relative to an unfamiliar region and show that by using them to model the interaction between an image’s known and unknown objects, we can better detect new visual categories. Rather than mine for all categories from scratch, our method identifies new objects while drawing on useful cues from familiar ones. We evaluate our approach on several benchmark data sets and demonstrate clear improvements in discovery over conventional purely appearance-based baselines.

"Commentary": Object and Spatial Visualization in Geosciences

ERIC Educational Resources Information Center

Kastens, Kim

2010-01-01

Cognitive science research shows that the brain has two systems for processing visual information, one specialized for spatial information such as position, orientation, and trajectory, and the other specialized for information used to identify objects, such as color, shape and texture. Some individuals seem to be more facile with the spatial…

Casimir Repulsion between Metallic Objects in Vacuum

DTIC Science & Technology

2010-08-27

levitation , as the particle is unstable to displacements away from the symmetry axis. DOI: 10.1103/PhysRevLett.105.090403 PACS numbers: 03.70.+k, 03.65.w...force. The geometry consists of an elongated metal particle centered above a metal plate with a hole. We prove that this geometry has a repulsive regime...ever be repulsive? In this Letter, we answer this question in the affirmative by showing that a small elongated metal particle centered above a thin

An Objective Rationale for the Choice of Regularisation Parameter with Application to Global Multiple-Frequency S-Wave Tomography

NASA Astrophysics Data System (ADS)

Zaroli, C.; Sambridge, M.; Leveque, J. J.; Debayle, E.; Nolet, G.

2014-12-01

In a linear ill-posed inverse problem, the regularisation parameter (damping) controls the balance between minimising both the residual data misfit and the model norm. Poor knowledge of data uncertainties often makes the selection of damping rather arbitrary. To go beyond that subjectivity, an objective rationale for the choice of damping is presented, which is based on the coherency of delay-time estimates in different frequency bands. Our method is tailored to the problem of global Multiple-Frequency Tomography, using a data set of 287078 S-wave delay-times measured in five frequency bands (10, 15, 22, 34, 51 s central periods). Whereas for each ray path the delay-time estimates should vary coherently from one period to the other, the noise most likely is not coherent. Thus, the lack of coherency of the information in different frequency bands is exploited, using an analogy with the cross-validation method, to identify models dominated by noise.In addition, a sharp change of behaviour of the model infinity-norm, as the damping becomes lower than a threshold value, is interpreted as the signature of data noise starting to significantly pollute at least one model component. Models with damping larger than this threshold are diagnosed as being constructed with poor data exploitation.Finally, a preferred model is selected from the remaining range of permitted model solutions. This choice is quasi-objective in terms of model interpretation, as the selected model shows a high degree of similarity with almost all other permitted models. The obtained tomographic model is displayed in mid lower-mantle (660-1910 km depth), and is shown to be mostly compatible with three other recent global shear-velocity models, while significant differences can be noticed. A wider application of the presented rationale should permit us to converge towards more objective seismic imaging of the Earth's mantle, using as much as possible of the relevant structural information in the data

Learning to explore the structure of kinematic objects in a virtual environment

PubMed Central

Buckmann, Marcus; Gaschler, Robert; Höfer, Sebastian; Loeben, Dennis; Frensch, Peter A.; Brock, Oliver

2015-01-01

The current study tested the quantity and quality of human exploration learning in a virtual environment. Given the everyday experience of humans with physical object exploration, we document substantial practice gains in the time, force, and number of actions needed to classify the structure of virtual chains, marking the joints as revolute, prismatic, or rigid. In line with current work on skill acquisition, participants could generalize the new and efficient psychomotor patterns of object exploration to novel objects. On the one hand, practice gains in exploration performance could be captured by a negative exponential practice function. On the other hand, they could be linked to strategies and strategy change. After quantifying how much was learned in object exploration and identifying the time course of practice-related gains in exploration efficiency (speed), we identified what was learned. First, we identified strategy components that were associated with efficient (fast) exploration performance: sequential processing, simultaneous use of both hands, low use of pulling rather than pushing, and low use of force. Only the latter was beneficial irrespective of the characteristics of the other strategy components. Second, we therefore characterized efficient exploration behavior by strategies that simultaneously take into account the abovementioned strategy components. We observed that participants maintained a high level of flexibility, sampling from a pool of exploration strategies trading the level of psycho-motoric challenges with exploration speed. We discuss the findings pursuing the aim of advancing intelligent object exploration by combining analytic (object exploration in humans) and synthetic work (object exploration in robots) in the same virtual environment. PMID:25904878

Educational Objectives of International Medical Electives – a narrative literature review

PubMed Central

Cherniak, William A.; Drain, Paul K.; Brewer, Timothy F.

2014-01-01

Purpose Most medical schools and residency programs offer international medical electives [IMEs], but there is little guidance on educational objectives for these rotations. We reviewed the literature to compile and categorize a comprehensive set of educational objectives for IMEs. Methods We conducted a narrative literature review with specified search criteria using SciVerse Scopus online, which includes Embase and Medline databases. From manuscripts that met inclusion criteria, we extracted data on educational objectives and sorted them into pre-elective, intra-elective, and post-elective categories. Results We identified and reviewed 255 articles, of which 11 (4%) manuscripts described 22 unique educational objectives. Among those, 5 (23%), 15 (68%), and 2 (9%) objectives were categorized in the pre-elective, intra-elective, and post-elective periods, respectively. Among pre-elective objectives, only cultural awareness was listed by more than two articles (3/11, 27%). Among intra-elective objectives, the most commonly defined objectives for students were enhancing clinical skills and understanding different health care systems (9/11, 82%). Learning to manage diseases rarely seen at home and increasing cultural awareness were described by nearly half (5/11, 46%) of all papers. Among post-elective objectives, reflecting on experiences through a written project was most common (9/11, 82%). Conclusions We identified 22 unique educational objectives for IMEs in the published literature, some of which were consistent. These consistencies can be used as a framework upon which institutions can build their own IME curriculums, ultimately helping to ensure that their students have a meaningful learning experience while abroad. PMID:24072105

A method of object recognition for single pixel imaging

NASA Astrophysics Data System (ADS)

Li, Boxuan; Zhang, Wenwen

2018-01-01

Computational ghost imaging(CGI), utilizing a single-pixel detector, has been extensively used in many fields. However, in order to achieve a high-quality reconstructed image, a large number of iterations are needed, which limits the flexibility of using CGI in practical situations, especially in the field of object recognition. In this paper, we purpose a method utilizing the feature matching to identify the number objects. In the given system, approximately 90% of accuracy of recognition rates can be achieved, which provides a new idea for the application of single pixel imaging in the field of object recognition

Use of an HIV-risk screening tool to identify optimal candidates for PrEP scale-up among men who have sex with men in Toronto, Canada: disconnect between objective and subjective HIV risk.

PubMed

Wilton, James; Kain, Taylor; Fowler, Shawn; Hart, Trevor A; Grennan, Troy; Maxwell, John; Tan, Darrell Hs

2016-01-01

Identifying appropriate pre-exposure prophylaxis (PrEP) candidates is a challenge in planning for the safe and effective roll-out of this strategy. We explored the use of a validated HIV risk screening tool, HIV Incidence Risk Index for Men who have Sex with Men (HIRI-MSM), to identify "optimal" candidates among MSM testing at a busy sexual health clinic's community testing sites in Toronto, Canada. Between November 2014 and April 2015, we surveyed MSM undergoing anonymous HIV testing at community testing sites in Toronto, Canada, to quantify "optimal" candidates for scaling up PrEP roll-out, defined as being at high objective HIV risk (scoring ≥10 on the HIRI-MSM), perceiving oneself at moderate-to-high HIV risk and being willing to use PrEP. Cascades were constructed to identify barriers to broader PrEP uptake. The association between HIRI-MSM score and both willingness to use PrEP and perceived HIV risk were explored in separate multivariable logistic regression analyses. Of 420 respondents, 64.4% were objectively at high risk, 52.5% were willing to use PrEP and 27.2% perceived themselves at moderate-to-high HIV risk. Only 16.4% were "optimal" candidates. Higher HIRI-MSM scores were positively associated with both willingness to use PrEP (aOR=1.7 per 10 score increase, 95%CI=1.3-2.2) and moderate-to-high perceived HIV risk (aOR=1.7 per 10 score increase, 95%CI=1.2-2.3). The proportion of men who were "optimal" candidates increased to 42.9% when the objective HIV risk cut-off was changed to top quartile of HIRI-MSM scores (≥26). In our full cascade, a very low proportion (5.3%) of MSM surveyed could potentially benefit from PrEP under current conditions. The greatest barrier in the cascade was low perception of HIV risk among high-risk men, but considerable numbers were also lost in downstream cascade steps. Of men at high objective HIV risk, 68.3% did not perceive themselves to be at moderate-to-high HIV risk, 23.6% were unaware of PrEP, 40.1% were not

Use of an HIV-risk screening tool to identify optimal candidates for PrEP scale-up among men who have sex with men in Toronto, Canada: disconnect between objective and subjective HIV risk

PubMed Central

Wilton, James; Kain, Taylor; Fowler, Shawn; Hart, Trevor A; Grennan, Troy; Maxwell, John; Tan, Darrell HS

2016-01-01

Introduction Identifying appropriate pre-exposure prophylaxis (PrEP) candidates is a challenge in planning for the safe and effective roll-out of this strategy. We explored the use of a validated HIV risk screening tool, HIV Incidence Risk Index for Men who have Sex with Men (HIRI-MSM), to identify “optimal” candidates among MSM testing at a busy sexual health clinic's community testing sites in Toronto, Canada. Methods Between November 2014 and April 2015, we surveyed MSM undergoing anonymous HIV testing at community testing sites in Toronto, Canada, to quantify “optimal” candidates for scaling up PrEP roll-out, defined as being at high objective HIV risk (scoring ≥10 on the HIRI-MSM), perceiving oneself at moderate-to-high HIV risk and being willing to use PrEP. Cascades were constructed to identify barriers to broader PrEP uptake. The association between HIRI-MSM score and both willingness to use PrEP and perceived HIV risk were explored in separate multivariable logistic regression analyses. Results Of 420 respondents, 64.4% were objectively at high risk, 52.5% were willing to use PrEP and 27.2% perceived themselves at moderate-to-high HIV risk. Only 16.4% were “optimal” candidates. Higher HIRI-MSM scores were positively associated with both willingness to use PrEP (aOR=1.7 per 10 score increase, 95%CI=1.3–2.2) and moderate-to-high perceived HIV risk (aOR=1.7 per 10 score increase, 95%CI=1.2–2.3). The proportion of men who were “optimal” candidates increased to 42.9% when the objective HIV risk cut-off was changed to top quartile of HIRI-MSM scores (≥26). In our full cascade, a very low proportion (5.3%) of MSM surveyed could potentially benefit from PrEP under current conditions. The greatest barrier in the cascade was low perception of HIV risk among high-risk men, but considerable numbers were also lost in downstream cascade steps. Of men at high objective HIV risk, 68.3% did not perceive themselves to be at moderate-to-high HIV risk

A practical approach to object based requirements analysis

NASA Technical Reports Server (NTRS)

Drew, Daniel W.; Bishop, Michael

1988-01-01

Presented here is an approach developed at the Unisys Houston Operation Division, which supports the early identification of objects. This domain oriented analysis and development concept is based on entity relationship modeling and object data flow diagrams. These modeling techniques, based on the GOOD methodology developed at the Goddard Space Flight Center, support the translation of requirements into objects which represent the real-world problem domain. The goal is to establish a solid foundation of understanding before design begins, thereby giving greater assurance that the system will do what is desired by the customer. The transition from requirements to object oriented design is also promoted by having requirements described in terms of objects. Presented is a five step process by which objects are identified from the requirements to create a problem definition model. This process involves establishing a base line requirements list from which an object data flow diagram can be created. Entity-relationship modeling is used to facilitate the identification of objects from the requirements. An example is given of how semantic modeling may be used to improve the entity-relationship model and a brief discussion on how this approach might be used in a large scale development effort.

Identifying resource manager information needs for the North Pacific Landscape Conservation Cooperative

USGS Publications Warehouse

Woodward, Andrea; Liedtke, Theresa; Jenni, Karen

2014-01-01

Landscape Conservation Cooperatives (LCCs) are a network of 22 public-private partnerships, defined by ecoregion, that share and provide science to ensure the sustainability of land, water, wildlife and cultural resources in North America. LLCs were established by the U.S. Department of Interior (DOI) in recognition that response to climate change must be coordinated on a landscape-level basis because important resources, ecosystem processes and resource management challenges extend beyond national wildlife refuges, Bureau of Land Management lands, national parks, and even international boundaries. Therefore, DOI agencies must work with other Federal, State, Tribal (U.S. indigenous peoples), First Nation (Canadian indigenous peoples), and local governments, as well as private landowners, to develop landscape-level strategies for understanding and responding to climate change.

Temperature data acquired from the DOI/GTN-P Deep Borehole Array on the Arctic Slope of Alaska, 1973-2013

USGS Publications Warehouse

Clow, Gary D.

2014-01-01

System (GTOS). The data will also be useful for refining our basic understanding of the physical conditions in permafrost in Arctic Alaska, as well as providing important information for validating predictive models used for climate impact assessments. The processed data are available from the Advanced Cooperative Arctic Data and Information Service (ACADIS) repository at doi:10.5065/D6N014HK.

Numerical Analysis Objects

NASA Astrophysics Data System (ADS)

Henderson, Michael

1997-08-01

The Numerical Analysis Objects project (NAO) is a project in the Mathematics Department of IBM's TJ Watson Research Center. While there are plenty of numerical tools available today, it is not an easy task to combine them into a custom application. NAO is directed at the dual problems of building applications from a set of tools, and creating those tools. There are several "reuse" projects, which focus on the problems of identifying and cataloging tools. NAO is directed at the specific context of scientific computing. Because the type of tools is restricted, problems such as tools with incompatible data structures for input and output, and dissimilar interfaces to tools which solve similar problems can be addressed. The approach we've taken is to define interfaces to those objects used in numerical analysis, such as geometries, functions and operators, and to start collecting (and building) a set of tools which use these interfaces. We have written a class library (a set of abstract classes and implementations) in C++ which demonstrates the approach. Besides the classes, the class library includes "stub" routines which allow the library to be used from C or Fortran, and an interface to a Visual Programming Language. The library has been used to build a simulator for petroleum reservoirs, using a set of tools for discretizing nonlinear differential equations that we have written, and includes "wrapped" versions of packages from the Netlib repository. Documentation can be found on the Web at "http://www.research.ibm.com/nao". I will describe the objects and their interfaces, and give examples ranging from mesh generation to solving differential equations.

Spondylolisthesis Identified Using Ultrasound Imaging.

PubMed

Beneck, George J; Gard, Andrea N; Fodran, Kimberly A

2017-12-01

57-year-old woman was recruited for a research study of muscle activation in persons with low back pain. She described a progressive worsening of left lower lumbar pain, which began 5 years prior without any precipitating incident, and intermittent pain at the left gluteal fold (diagnosed as a proximal hamstring tear 2 years prior). Ultrasound revealed marked anterior displacement of the L3-4 and L4-5 facet joints. The subject was recommended for a radiograph using a lateral recumbent view, which demonstrated a grade II spondylolisthesis. J Orthop Sports Phys Ther 2017;47(12):970. doi:10.2519/jospt.2017.7363.

3-D Object Recognition from Point Cloud Data

NASA Astrophysics Data System (ADS)

Smith, W.; Walker, A. S.; Zhang, B.

2011-09-01

The market for real-time 3-D mapping includes not only traditional geospatial applications but also navigation of unmanned autonomous vehicles (UAVs). Massively parallel processes such as graphics processing unit (GPU) computing make real-time 3-D object recognition and mapping achievable. Geospatial technologies such as digital photogrammetry and GIS offer advanced capabilities to produce 2-D and 3-D static maps using UAV data. The goal is to develop real-time UAV navigation through increased automation. It is challenging for a computer to identify a 3-D object such as a car, a tree or a house, yet automatic 3-D object recognition is essential to increasing the productivity of geospatial data such as 3-D city site models. In the past three decades, researchers have used radiometric properties to identify objects in digital imagery with limited success, because these properties vary considerably from image to image. Consequently, our team has developed software that recognizes certain types of 3-D objects within 3-D point clouds. Although our software is developed for modeling, simulation and visualization, it has the potential to be valuable in robotics and UAV applications. The locations and shapes of 3-D objects such as buildings and trees are easily recognizable by a human from a brief glance at a representation of a point cloud such as terrain-shaded relief. The algorithms to extract these objects have been developed and require only the point cloud and minimal human inputs such as a set of limits on building size and a request to turn on a squaring option. The algorithms use both digital surface model (DSM) and digital elevation model (DEM), so software has also been developed to derive the latter from the former. The process continues through the following steps: identify and group 3-D object points into regions; separate buildings and houses from trees; trace region boundaries; regularize and simplify boundary polygons; construct complex roofs. Several case

System and method for automated object detection in an image

DOEpatents

Kenyon, Garrett T.; Brumby, Steven P.; George, John S.; Paiton, Dylan M.; Schultz, Peter F.

2015-10-06

A contour/shape detection model may use relatively simple and efficient kernels to detect target edges in an object within an image or video. A co-occurrence probability may be calculated for two or more edge features in an image or video using an object definition. Edge features may be differentiated between in response to measured contextual support, and prominent edge features may be extracted based on the measured contextual support. The object may then be identified based on the extracted prominent edge features.

Buried object remote detection technology for law enforcement

DOE Office of Scientific and Technical Information (OSTI.GOV)

Del Grande, N.K.; Clark, G.A.; Durbin, P.F.

1991-03-01

We have developed a precise airborne temperature-sensing technology to detect buried objects for use by law enforcement. Demonstrations have imaged the sites of buried foundations, walls and trenches; mapped underground waterways and aquifers; and been used to locate underground military objects. Our patented methodology is incorporated in a commercially available, high signal-to-noise, dual-band infrared scanner with real-time, 12-bit digital image processing software and display. Our method creates color-coded images based on surface temperature variations of 0.2 {degrees}C. Unlike other less-sensitive methods, it maps true (corrected) temperatures by removing the (decoupled) surface emissivity mask equivalent to 1{degrees}C or 2{degrees}C; this maskmore » hinders interpretation of apparent (blackbody) temperatures. Once removed, were are able to identify surface temperature patterns from small diffusivity changes at buried object sites which heat and cool differently from their surroundings. Objects made of different materials and buried at different depths are identified by their unique spectra, spatial, thermal, temporal, emissivity and diffusivity signatures. We have successfully located the sites of buried (inert) simulated land mines 0.1 to 0.2 m deep; sod-covered rock pathways alongside dry ditches, deeper than 0.2 m; pavement covered burial trenches and cemetery structures as deep as 0.8 m; and aquifers more than 6 m and less 60 m deep. Our technology could be adapted for drug interdiction and pollution control. 16 refs., 14 figs.« less

Object-processing neural efficiency differentiates object from spatial visualizers.

PubMed

Motes, Michael A; Malach, Rafael; Kozhevnikov, Maria

2008-11-19

The visual system processes object properties and spatial properties in distinct subsystems, and we hypothesized that this distinction might extend to individual differences in visual processing. We conducted a functional MRI study investigating the neural underpinnings of individual differences in object versus spatial visual processing. Nine participants of high object-processing ability ('object' visualizers) and eight participants of high spatial-processing ability ('spatial' visualizers) were scanned, while they performed an object-processing task. Object visualizers showed lower bilateral neural activity in lateral occipital complex and lower right-lateralized neural activity in dorsolateral prefrontal cortex. The data indicate that high object-processing ability is associated with more efficient use of visual-object resources, resulting in less neural activity in the object-processing pathway.

The subjective experience of object recognition: comparing metacognition for object detection and object categorization.

PubMed

Meuwese, Julia D I; van Loon, Anouk M; Lamme, Victor A F; Fahrenfort, Johannes J

2014-05-01

Perceptual decisions seem to be made automatically and almost instantly. Constructing a unitary subjective conscious experience takes more time. For example, when trying to avoid a collision with a car on a foggy road you brake or steer away in a reflex, before realizing you were in a near accident. This subjective aspect of object recognition has been given little attention. We used metacognition (assessed with confidence ratings) to measure subjective experience during object detection and object categorization for degraded and masked objects, while objective performance was matched. Metacognition was equal for degraded and masked objects, but categorization led to higher metacognition than did detection. This effect turned out to be driven by a difference in metacognition for correct rejection trials, which seemed to be caused by an asymmetry of the distractor stimulus: It does not contain object-related information in the detection task, whereas it does contain such information in the categorization task. Strikingly, this asymmetry selectively impacted metacognitive ability when objective performance was matched. This finding reveals a fundamental difference in how humans reflect versus act on information: When matching the amount of information required to perform two tasks at some objective level of accuracy (acting), metacognitive ability (reflecting) is still better in tasks that rely on positive evidence (categorization) than in tasks that rely more strongly on an absence of evidence (detection).

Shape detection of Gaborized outline versions of everyday objects

PubMed Central

Sassi, Michaël; Machilsen, Bart; Wagemans, Johan

2012-01-01

We previously tested the identifiability of six versions of Gaborized outlines of everyday objects, differing in the orientations assigned to elements inside and outside the outline. We found significant differences in identifiability between the versions, and related a number of stimulus metrics to identifiability [Sassi, M., Vancleef, K., Machilsen, B., Panis, S., & Wagemans, J. (2010). Identification of everyday objects on the basis of Gaborized outline versions. i-Perception, 1(3), 121–142]. In this study, after retesting the identifiability of new variants of three of the stimulus versions, we tested their robustness to local orientation jitter in a detection experiment. In general, our results replicated the key findings from the previous study, and allowed us to substantiate our earlier interpretations of the effects of our stimulus metrics and of the performance differences between the different stimulus versions. The results of the detection task revealed a different ranking order of stimulus versions than the identification task. By examining the parallels and differences between the effects of our stimulus metrics in the two tasks, we found evidence for a trade-off between shape detectability and identifiability. The generally simple and smooth shapes that yield the strongest contour integration and most robust detectability tend to lack the distinguishing features necessary for clear-cut identification. Conversely, contours that do contain such identifying features tend to be inherently more complex and, therefore, yield weaker integration and less robust detectability. PMID:23483752

Methods for identifying high collision concentration locations (HCCL) for potential safety improvements : phase II, Evaluation of alternative methods for identifying HCCL.

DOT National Transportation Integrated Search

2011-01-01

The objective of network screening should ideally be to not only identify sites for safety : investigation but also to prioritize those sites efficiently. Using roadway, intersection, and : collision data from California, this study compared the perf...

Location of geographical objects in crisis situations

NASA Astrophysics Data System (ADS)

Rybansky, M.; Kratochvil, V.

2014-02-01

This article summarizes the various expressions of object positioning using different coordinate data and different methods, such as use of maps, exploiting the properties of digital Global System for Mobile Communications (GSM) networks, Global Navigational Satellite Systems (GNSS), Inertial Navigation Systems (INS), Inertial Measurement Systems (IMS), hybrid methods and non-contact (remote sensing) methods; all with varying level of accuracy. Furthermore, the article describes some geographical identifiers and verbal means to describe location of geographical objects such as settlements, rivers, forest, roads, etc. All of the location methods have some advantages and disadvantages, especially in emergency situations, when usually the crisis management has a lack of time in a decision process.

Integrating regional conservation priorities for multiple objectives into national policy

PubMed Central

Beger, Maria; McGowan, Jennifer; Treml, Eric A.; Green, Alison L.; White, Alan T.; Wolff, Nicholas H.; Klein, Carissa J.; Mumby, Peter J.; Possingham, Hugh P.

2015-01-01

Multinational conservation initiatives that prioritize investment across a region invariably navigate trade-offs among multiple objectives. It seems logical to focus where several objectives can be achieved efficiently, but such multi-objective hotspots may be ecologically inappropriate, or politically inequitable. Here we devise a framework to facilitate a regionally cohesive set of marine-protected areas driven by national preferences and supported by quantitative conservation prioritization analyses, and illustrate it using the Coral Triangle Initiative. We identify areas important for achieving six objectives to address ecosystem representation, threatened fauna, connectivity and climate change. We expose trade-offs between areas that contribute substantially to several objectives and those meeting one or two objectives extremely well. Hence there are two strategies to guide countries choosing to implement regional goals nationally: multi-objective hotspots and complementary sets of single-objective priorities. This novel framework is applicable to any multilateral or global initiative seeking to apply quantitative information in decision making. PMID:26364769

On the objective identification of flood seasons

NASA Astrophysics Data System (ADS)

Cunderlik, Juraj M.; Ouarda, Taha B. M. J.; BobéE, Bernard

2004-01-01

The determination of seasons of high and low probability of flood occurrence is a task with many practical applications in contemporary hydrology and water resources management. Flood seasons are generally identified subjectively by visually assessing the temporal distribution of flood occurrences and, then at a regional scale, verified by comparing the temporal distribution with distributions obtained at hydrologically similar neighboring sites. This approach is subjective, time consuming, and potentially unreliable. The main objective of this study is therefore to introduce a new, objective, and systematic method for the identification of flood seasons. The proposed method tests the significance of flood seasons by comparing the observed variability of flood occurrences with the theoretical flood variability in a nonseasonal model. The method also addresses the uncertainty resulting from sampling variability by quantifying the probability associated with the identified flood seasons. The performance of the method was tested on an extensive number of samples with different record lengths generated from several theoretical models of flood seasonality. The proposed approach was then applied on real data from a large set of sites with different flood regimes across Great Britain. The results show that the method can efficiently identify flood seasons from both theoretical and observed distributions of flood occurrence. The results were used for the determination of the main flood seasonality types in Great Britain.

Object-based warping: an illusory distortion of space within objects.

PubMed

Vickery, Timothy J; Chun, Marvin M

2010-12-01

Visual objects are high-level primitives that are fundamental to numerous perceptual functions, such as guidance of attention. We report that objects warp visual perception of space in such a way that spatial distances within objects appear to be larger than spatial distances in ground regions. When two dots were placed inside a rectangular object, they appeared farther apart from one another than two dots with identical spacing outside of the object. To investigate whether this effect was object based, we measured the distortion while manipulating the structure surrounding the dots. Object displays were constructed with a single object, multiple objects, a partially occluded object, and an illusory object. Nonobject displays were constructed to be comparable to object displays in low-level visual attributes. In all cases, the object displays resulted in a more powerful distortion of spatial perception than comparable non-object-based displays. These results suggest that perception of space within objects is warped.

The role of serotonin-2 (5-HT2) and dopamine receptors in the behavioral actions of the 5-HT2A/2C agonist, DOI, and putative 5-HT2C inverse agonist, SR46349B.

PubMed

Scarlota, Laura C; Harvey, John A; Aloyo, Vincent J

2011-02-01

Atypical antipsychotic efficacy is often attributed to actions at serotonin-2 (5-HT(2)) and dopamine receptors, indicating a potential benefit of understanding the interplay between these systems. Currently, it is known that 5-HT(2) receptors modulate dopamine release, although the role of specific dopamine receptors in 5-HT(2)-mediated behavior is not well understood. We examined the role of 5-HT(2A), 5-HT(2C), and dopamine (D1 and D2) receptors in the behavioral response to a 5-HT(2A/2C) agonist (DOI) and 5-HT(2A/2C) antagonist (SR46349B). Effects were assessed by measuring rabbit head bobs (previously characterized as 5-HT(2A) receptor-mediated) and body shakes (5-HT(2C)-mediated). As expected, DOI produced head bobs and body shakes, and these DOI-elicited behaviors were attenuated by the SR46349B pretreatment. Unexpectedly, SR46349B also induced head bobs when administered alone. However, SR46349B-elicited head bobs are distinguishable from those produced by DOI since the 5-HT(2A) antagonist, ketanserin, only attenuated DOI-elicited head bobs. Conversely, 5-HT(2C) ligands (SB242084 and SB206553) inhibited SR46349B but not DOI-induced head bobs. Furthermore, when administered alone, SB206553 (a 5-HT(2C) inverse agonist) produced head bobs, indicating the behavior can be either 5-HT(2A) or 5-HT(2C) mediated. Next, it was revealed that D1 and D2 receptors play a role in DOI-elicited head bobs, but only D1 receptors are required for SR46349B-elicited head bobs. 5-HT(2A) receptor agonism and 5-HT(2C) inverse agonism produce the same behavior, likely due to similar downstream actions at D1 receptors. Consequently, 5-HT(2C) agonism or D1 agonism may be effective therapies for disorders, such as schizophrenia, currently being treated with 5-HT(2A) antagonists.

American Literature: Performance Objectives and Classroom Activities.

ERIC Educational Resources Information Center

Ascher, Hope; And Others

This guide is a sampler of ideas and activities based on 22 minimum objectives in speech, reading, writing, and research that have been identified for American literature study. Many of the activities involve an integration of several skills that are cross-referenced to other skills in the margins of the guide. A separate section on research…

Effects of visual cues of object density on perception and anticipatory control of dexterous manipulation.

PubMed

Crajé, Céline; Santello, Marco; Gordon, Andrew M

2013-01-01

Anticipatory force planning during grasping is based on visual cues about the object's physical properties and sensorimotor memories of previous actions with grasped objects. Vision can be used to estimate object mass based on the object size to identify and recall sensorimotor memories of previously manipulated objects. It is not known whether subjects can use density cues to identify the object's center of mass (CM) and create compensatory moments in an anticipatory fashion during initial object lifts to prevent tilt. We asked subjects (n = 8) to estimate CM location of visually symmetric objects of uniform densities (plastic or brass, symmetric CM) and non-uniform densities (mixture of plastic and brass, asymmetric CM). We then asked whether subjects can use density cues to scale fingertip forces when lifting the visually symmetric objects of uniform and non-uniform densities. Subjects were able to accurately estimate an object's center of mass based on visual density cues. When the mass distribution was uniform, subjects could scale their fingertip forces in an anticipatory fashion based on the estimation. However, despite their ability to explicitly estimate CM location when object density was non-uniform, subjects were unable to scale their fingertip forces to create a compensatory moment and prevent tilt on initial lifts. Hefting object parts in the hand before the experiment did not affect this ability. This suggests a dichotomy between the ability to accurately identify the object's CM location for objects with non-uniform density cues and the ability to utilize this information to correctly scale their fingertip forces. These results are discussed in the context of possible neural mechanisms underlying sensorimotor integration linking visual cues and anticipatory control of grasping.

Genome Wide Gene by Environment Interaction Analysis Identifies Common SNPs at 17q21.2 that Are Associated with Increased Body Mass Index Only among Asthmatics

DTIC Science & Technology

2015-12-16

polymorphisms (SNPs), a candidate gene association study was conducted to identify shared genetic variants between childhood asthma and obesity , but no SNP was...10):969– 76. doi: 10.1093/aje/kwh303 PMID: 15522853. 33. von Kries R, Hermann M, Grunert VP, von Mutius E. Is obesity a risk factor for childhood ...88PA, Case # 2014-4685, 7 Oct 2014. PLoS One. 2015; 10(12):e0144114. 14. ABSTRACT Asthmatics have an increased risk of being overweight/ obese

Citation Classics in the Burn Literature During the Past 55 Years

DTIC Science & Technology

2014-04-01

Association. 1559-047X/2014 DOI: 10.1097/BCR.0b013e31828cb25e The objective of this study was to identify the 100 most cited, peer-reviewed burn -related...the goal of this study was to identify and analyze the 100 most cited burn -related articles published in the peer-reviewed biomedical literature...Figure 1) illustrates the substantial increase in burn -related articles cited during the study period. The year of publication ranged from 1955 to

A multi-objective decision-making approach to the journal submission problem.

PubMed

Wong, Tony E; Srikrishnan, Vivek; Hadka, David; Keller, Klaus

2017-01-01

When researchers complete a manuscript, they need to choose a journal to which they will submit the study. This decision requires to navigate trade-offs between multiple objectives. One objective is to share the new knowledge as widely as possible. Citation counts can serve as a proxy to quantify this objective. A second objective is to minimize the time commitment put into sharing the research, which may be estimated by the total time from initial submission to final decision. A third objective is to minimize the number of rejections and resubmissions. Thus, researchers often consider the trade-offs between the objectives of (i) maximizing citations, (ii) minimizing time-to-decision, and (iii) minimizing the number of resubmissions. To complicate matters further, this is a decision with multiple, potentially conflicting, decision-maker rationalities. Co-authors might have different preferences, for example about publishing fast versus maximizing citations. These diverging preferences can lead to conflicting trade-offs between objectives. Here, we apply a multi-objective decision analytical framework to identify the Pareto-front between these objectives and determine the set of journal submission pathways that balance these objectives for three stages of a researcher's career. We find multiple strategies that researchers might pursue, depending on how they value minimizing risk and effort relative to maximizing citations. The sequences that maximize expected citations within each strategy are generally similar, regardless of time horizon. We find that the "conditional impact factor"-impact factor times acceptance rate-is a suitable heuristic method for ranking journals, to strike a balance between minimizing effort objectives and maximizing citation count. Finally, we examine potential co-author tension resulting from differing rationalities by mapping out each researcher's preferred Pareto front and identifying compromise submission strategies. The explicit

New Herbig-Haro objects in star-forming regions

NASA Technical Reports Server (NTRS)

Reipurth, BO; Graham, J. A.

1988-01-01

A list of 25 new Herbig-Haro objects, HH 58 to HH 82, in the Orion molecular clouds and in southern molecular cloud complexes has been compiled. CCD images in the S II 6717, 6731 forbidden lines are presented for the objects, together with a few spectra and some IR observations. The individual objects and, when identified, their energy sources are discussed. HH 65 is located in the red lobe of the bipolar outflow associated with the highly variable reflection nebula Re 50. HH 67 is a 22-arcsec long sinusoidal jet. HH 68/69 consists of a long, linear chain of four HH knots. HH 72 emerges from a 120-solar luminosity IRAS source embedded in a Bok globule. HH 79 is the first HH object discovered in the Ophiuchus clouds. HH 80/81 in Sagittarius are among the brightest HH objects known, have complex velocities, high excitation conditions and emerge from a 6000-solar luminosity young B-star. HH 82 is associated with the bright variable star S Coronae Australis.

Optimizing Monitoring Designs under Alternative Objectives

DOE PAGES

Gastelum, Jason A.; USA, Richland Washington; Porter, Ellen A.; ...

2014-12-31

This paper describes an approach to identify monitoring designs that optimize detection of CO2 leakage from a carbon capture and sequestration (CCS) reservoir and compares the results generated under two alternative objective functions. The first objective function minimizes the expected time to first detection of CO2 leakage, the second more conservative objective function minimizes the maximum time to leakage detection across the set of realizations. The approach applies a simulated annealing algorithm that searches the solution space by iteratively mutating the incumbent monitoring design. The approach takes into account uncertainty by evaluating the performance of potential monitoring designs across amore » set of simulated leakage realizations. The approach relies on a flexible two-tiered signature to infer that CO2 leakage has occurred. This research is part of the National Risk Assessment Partnership, a U.S. Department of Energy (DOE) project tasked with conducting risk and uncertainty analysis in the areas of reservoir performance, natural leakage pathways, wellbore integrity, groundwater protection, monitoring, and systems level modeling.« less

Exploration of complex visual feature spaces for object perception

PubMed Central

Leeds, Daniel D.; Pyles, John A.; Tarr, Michael J.

2014-01-01

The mid- and high-level visual properties supporting object perception in the ventral visual pathway are poorly understood. In the absence of well-specified theory, many groups have adopted a data-driven approach in which they progressively interrogate neural units to establish each unit's selectivity. Such methods are challenging in that they require search through a wide space of feature models and stimuli using a limited number of samples. To more rapidly identify higher-level features underlying human cortical object perception, we implemented a novel functional magnetic resonance imaging method in which visual stimuli are selected in real-time based on BOLD responses to recently shown stimuli. This work was inspired by earlier primate physiology work, in which neural selectivity for mid-level features in IT was characterized using a simple parametric approach (Hung et al., 2012). To extend such work to human neuroimaging, we used natural and synthetic object stimuli embedded in feature spaces constructed on the basis of the complex visual properties of the objects themselves. During fMRI scanning, we employed a real-time search method to control continuous stimulus selection within each image space. This search was designed to maximize neural responses across a pre-determined 1 cm3 brain region within ventral cortex. To assess the value of this method for understanding object encoding, we examined both the behavior of the method itself and the complex visual properties the method identified as reliably activating selected brain regions. We observed: (1) Regions selective for both holistic and component object features and for a variety of surface properties; (2) Object stimulus pairs near one another in feature space that produce responses at the opposite extremes of the measured activity range. Together, these results suggest that real-time fMRI methods may yield more widely informative measures of selectivity within the broad classes of visual features

Patterns of muscle activity underlying object-specific grasp by the macaque monkey.

PubMed

Brochier, T; Spinks, R L; Umilta, M A; Lemon, R N

2004-09-01

During object grasp, a coordinated activation of distal muscles is required to shape the hand in relation to the physical properties of the object. Despite the fundamental importance of the grasping action, little is known of the muscular activation patterns that allow objects of different sizes and shapes to be grasped. In a study of two adult macaque monkeys, we investigated whether we could distinguish between EMG activation patterns associated with grasp of 12 differently shaped objects, chosen to evoke a wide range of grasping postures. Each object was mounted on a horizontal shuttle held by a weak spring (load force 1-2 N). Objects were located in separate sectors of a "carousel," and inter-trial rotation of the carousel allowed sequential presentation of the objects in pseudorandom order. EMG activity from 10 to 12 digit, hand, and arm muscles was recorded using chronically implanted electrodes. We show that the grasp of different objects was characterized by complex but distinctive patterns of EMG activation. Cluster analysis shows that these object-related EMG patterns were specific and consistent enough to identify the object unequivocally from the EMG recordings alone. EMG-based object identification required a minimum of six EMGs from simultaneously recorded muscles. EMG patterns were consistent across recording sessions in a given monkey but showed some differences between animals. These results identify the specific patterns of activity required to achieve distinct hand postures for grasping, and they open the way to our understanding of how these patterns are generated by the central motor network.

Acoustic facilitation of object movement detection during self-motion

PubMed Central

Calabro, F. J.; Soto-Faraco, S.; Vaina, L. M.

2011-01-01

In humans, as well as most animal species, perception of object motion is critical to successful interaction with the surrounding environment. Yet, as the observer also moves, the retinal projections of the various motion components add to each other and extracting accurate object motion becomes computationally challenging. Recent psychophysical studies have demonstrated that observers use a flow-parsing mechanism to estimate and subtract self-motion from the optic flow field. We investigated whether concurrent acoustic cues for motion can facilitate visual flow parsing, thereby enhancing the detection of moving objects during simulated self-motion. Participants identified an object (the target) that moved either forward or backward within a visual scene containing nine identical textured objects simulating forward observer translation. We found that spatially co-localized, directionally congruent, moving auditory stimuli enhanced object motion detection. Interestingly, subjects who performed poorly on the visual-only task benefited more from the addition of moving auditory stimuli. When auditory stimuli were not co-localized to the visual target, improvements in detection rates were weak. Taken together, these results suggest that parsing object motion from self-motion-induced optic flow can operate on multisensory object representations. PMID:21307050

Hydro-geomorphic connectivity and landslide features extraction to identifying potential threats and hazardous areas

NASA Astrophysics Data System (ADS)

Tarolli, Paolo; Fuller, Ian C.; Basso, Federica; Cavalli, Marco; Sofia, Giulia

2017-04-01

Hydro-geomorphic connectivity has significantly emerged as a new concept to understand the transfer of surface water and sediment through landscapes. A further scientific challenge is determining how the concept can be used to enable sustainable land and water management. This research proposes an interesting approach to integrating remote sensing techniques, connectivity theory, and geomorphometry based on high-resolution digital terrain model (HR-DTMs) to automatically extract landslides crowns and gully erosion, to determine the different rate of connectivity among the main extracted features and the river network, and thus determine a possible categorization of hazardous areas. The study takes place in two mountainous regions in the Wellington Region (New Zealand). The methodology is a three step approach. Firstly, we performed an automatic detection of the likely landslides crowns through the use of thresholds obtained by the statistical analysis of the variability of landform curvature. After that, the research considered the Connectivity Index to analyse how a complex and rugged topography induces large variations in erosion and sediment delivery in the two catchments. Lastly, the two methods have been integrated to create a unique procedure able to classify the different rate of connectivity among the main features and the river network and thus identifying potential threats and hazardous areas. The methodology is fast, and it can produce a detailed and updated inventory map that could be a key tool for erosional and sediment delivery hazard mitigation. This fast and simple method can be a useful tool to manage emergencies giving priorities to more failure-prone zones. Furthermore, it could be considered to do a preliminary interpretations of geomorphological phenomena and more in general, it could be the base to develop inventory maps. References Cavalli M, Trevisani S, Comiti F, Marchi L. 2013. Geomorphometric assessment of spatial sediment connectivity

40 CFR 255.11 - Criteria for identifying agencies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... quality management planning agencies designated under section 208 of the Federal Water Pollution Control... State water quality management agencies. (d) Planning objectives will influence agency selection... IDENTIFICATION OF REGIONS AND AGENCIES FOR SOLID WASTE MANAGEMENT Criteria for Identifying Regions and Agencies...

Object extraction in photogrammetric computer vision

NASA Astrophysics Data System (ADS)

Mayer, Helmut

This paper discusses state and promising directions of automated object extraction in photogrammetric computer vision considering also practical aspects arising for digital photogrammetric workstations (DPW). A review of the state of the art shows that there are only few practically successful systems on the market. Therefore, important issues for a practical success of automated object extraction are identified. A sound and most important powerful theoretical background is the basis. Here, we particularly point to statistical modeling. Testing makes clear which of the approaches are suited best and how useful they are for praxis. A key for commercial success of a practical system is efficient user interaction. As the means for data acquisition are changing, new promising application areas such as extremely detailed three-dimensional (3D) urban models for virtual television or mission rehearsal evolve.

Linking objects in the process of mourning for sons disappeared in war: Croatia 2001.

PubMed

Jurcević, Slavica; Urlić, Ivan

2002-04-01

Mothers use linking object to externalize the complex aspects of their relationship to the loss of their child. We analyzed the linking objects that mothers kept in memory of their sons who disappeared in the 1991-1995 war in Croatia or whose remains were uncovered and identified long time after they had gone missing. The case study of disturbed mourning included 26 mothers of Croatian soldiers from Croatian Osijek-Baranja County who went missing in war or whose remains were recovered and identified long after they had gone missing. The mothers were selected independently by the president of the Association of Families of Missing and Detained Croatian Soldiers and agreed to participate in the study in 2001. They were interviewed in their homes, their testimonies were recorded, and photographs of the linking objects taken. Linking objects were classified according to the Volkan's four-group classification. Out of four Volkan's groups of linking objects, we identified the objects belonging to the first three. Those were 1) objects that had been worn by the deceased (clothes, wrist-watch, ring, or glasses), (6/26); 2) objects that could be viewed in the psychoanalytic sense as an extension of the body of the disappeared or dead person, such as a camera (4/26); and 3) objects with realistic or symbolic resemblance to the deceased, usually a photograph (8/26). None of the examined objects belonged to the fourth Volkan's group (objects at hand when the news of the death came or objects present at the funeral, things that could be considered last-minute objects, ie, related to the moment when the deceased was last seen alive). However, 8/26 objects formed a new hitherto undescribed group. Mothers used such objects to create a memorial shrine to their sons. A photograph of the missing person or person whose remains were identified long after he had gone missing occupied a central place at the shrine, and was surrounded by other symbols of the Catholic iconography (Virgin

Emerging Fabric of Science: Persistent Identifiers and Knowledge Networks

NASA Astrophysics Data System (ADS)

Hugo, W.

2017-12-01

There is an increasing emphasis on the use of persistent identifiers in the description of scientific activity, whether this is done to cite scholarly publications and research output, reliably identify role players such as funders and researchers, or to provide long-lasting references to controlled vocabulary. The ICSU World Data System has been promoting the establishment of a "Knowledge Network" to describe research activity, realising that parts of the network will be established as a federated `system', based on linkages between registries of persistent identifiers. In addition, there is a growing focus on not only the relationship between these major role players and associated digital objects, but also on the processes of science: provenance, reproducibility, and re-usability being significant topics of discussion. The paper will focus on description of the `Fabric of Science' from the perspectives of both structure and processes, review the state of implementation of real services and infrastructure in support of it. A case is made for inclusion of persistent identifiers into the mainstream activities of scientists and data infrastructure managers, and for the development of services, such as Scholix, to make better use of the relationships between digital objects and major role players. A proposal is made for the adoption of a federated system of services that are based on a hybrid graph-object framework similar to Scholix for recording the activity of scientific research. Finally, links to related ideas are explored: novel ways of representing of knowledge (such as Nanopublications) and the possibility that the publication paradigm currently in use may have to be amended.

Object Manipulation Facilitates Kind-Based Object Individuation of Shape-Similar Objects

ERIC Educational Resources Information Center

Kingo, Osman S.; Krojgaard, Peter

2011-01-01

Five experiments investigated the importance of shape and object manipulation when 12-month-olds were given the task of individuating objects representing exemplars of kinds in an event-mapping design. In Experiments 1 and 2, results of the study from Xu, Carey, and Quint (2004, Experiment 4) were partially replicated, showing that infants were…

Identifying Bright X-Ray Beasts

NASA Astrophysics Data System (ADS)

Kohler, Susanna

2017-10-01

Ultraluminous X-ray sources (ULXs) are astronomical sources of X-rays that, while dimmer than active galactic nuclei, are nonetheless brighter than any known stellar process. What are these beasts and why do they shine so brightly?Exceeding the LimitFirst discovered in the 1980s, ULXs are rare sources that have nonetheless been found in all types of galaxies. Though the bright X-ray radiation seems likely to be coming from compact objects accreting gas, theres a problem with this theory: ULXs outshine the Eddington luminosity for stellar-mass compact objects. This means that a stellar-mass object couldnt emit this much radiation isotropically without blowing itself apart.There are two alternative explanations commonly proposed for ULXs:Rather than being accreting stellar-mass compact objects, they are accreting intermediate-mass black holes. A hypothetical black hole of 100 solar masses or more would have a much higher Eddington luminosity than a stellar-mass black hole, making the luminosities that we observe from ULXs feasible.An example of one of the common routes the authors find for a binary system to become a ULX. In this case, the binary begins as two main sequence stars. As one star evolves off the main sequence, the binary undergoes a common envelope phase and a stage of mass transfer. The star ends its life as a supernova, and the resulting neutron star then accretes matter from the main sequence star as a ULX. [Wiktorowicz et al. 2017]They are ordinary X-ray binaries (a stellar-mass compact object accreting matter from a companion star), but they are undergoing a short phase of extreme accretion. During this time, their emission is beamed into jets, making them appear brighter than the Eddington luminosity.Clues from a New DiscoveryA few years ago, a new discovery shed some light on ULXs: M82 X-2, a pulsing ULX. Two more pulsing ULXs have been discovered since then, demonstrating that at least some ULXs contain pulsars i.e., neutron stars as the

Multi-objects recognition for distributed intelligent sensor networks

NASA Astrophysics Data System (ADS)

He, Haibo; Chen, Sheng; Cao, Yuan; Desai, Sachi; Hohil, Myron E.

2008-04-01

This paper proposes an innovative approach for multi-objects recognition for homeland security and defense based intelligent sensor networks. Unlike the conventional way of information analysis, data mining in such networks is typically characterized with high information ambiguity/uncertainty, data redundancy, high dimensionality and real-time constrains. Furthermore, since a typical military based network normally includes multiple mobile sensor platforms, ground forces, fortified tanks, combat flights, and other resources, it is critical to develop intelligent data mining approaches to fuse different information resources to understand dynamic environments, to support decision making processes, and finally to achieve the goals. This paper aims to address these issues with a focus on multi-objects recognition. Instead of classifying a single object as in the traditional image classification problems, the proposed method can automatically learn multiple objectives simultaneously. Image segmentation techniques are used to identify the interesting regions in the field, which correspond to multiple objects such as soldiers or tanks. Since different objects will come with different feature sizes, we propose a feature scaling method to represent each object in the same number of dimensions. This is achieved by linear/nonlinear scaling and sampling techniques. Finally, support vector machine (SVM) based learning algorithms are developed to learn and build the associations for different objects, and such knowledge will be adaptively accumulated for objects recognition in the testing stage. We test the effectiveness of proposed method in different simulated military environments.

Organizing and Typing Persistent Objects Within an Object-Oriented Framework

NASA Technical Reports Server (NTRS)

Madany, Peter W.; Campbell, Roy H.

1991-01-01

Conventional operating systems provide little or no direct support for the services required for an efficient persistent object system implementation. We have built a persistent object scheme using a customization and extension of an object-oriented operating system called Choices. Choices includes a framework for the storage of persistent data that is suited to the construction of both conventional file system and persistent object system. In this paper we describe three areas in which persistent object support differs from file system support: storage organization, storage management, and typing. Persistent object systems must support various sizes of objects efficiently. Customizable containers, which are themselves persistent objects and can be nested, support a wide range of object sizes in Choices. Collections of persistent objects that are accessed as an aggregate and collections of light-weight persistent objects can be clustered in containers that are nested within containers for larger objects. Automated garbage collection schemes are added to storage management and have a major impact on persistent object applications. The Choices persistent object store provides extensible sets of persistent object types. The store contains not only the data for persistent objects but also the names of the classes to which they belong and the code for the operation of the classes. Besides presenting persistent object storage organization, storage management, and typing, this paper discusses how persistent objects are named and used within the Choices persistent data/file system framework.

Action relations facilitate the identification of briefly-presented objects.

PubMed

Roberts, Katherine L; Humphreys, Glyn W

2011-02-01

The link between perception and action allows us to interact fluently with the world. Objects which 'afford' an action elicit a visuomotor response, facilitating compatible responses. In addition, positioning objects to interact with one another appears to facilitate grouping, indicated by patients with extinction being better able to identify interacting objects (e.g. a corkscrew going towards the top of a wine bottle) than the same objects when positioned incorrectly for action (Riddoch, Humphreys, Edwards, Baker, & Willson, Nature Neuroscience, 6, 82-89, 2003). Here, we investigate the effect of action relations on the perception of normal participants. We found improved identification of briefly-presented objects when in correct versus incorrect co-locations for action. For the object that would be 'active' in the interaction (the corkscrew), this improvement was enhanced when it was oriented for use by the viewer's dominant hand. In contrast, the position-related benefit for the 'passive' object was stronger when the objects formed an action-related pair (corkscrew and bottle) compared with an unrelated pair (corkscrew and candle), and it was reduced when spatial cues disrupted grouping between the objects. We propose that these results indicate two separate effects of action relations on normal perception: a visuomotor response to objects which strongly afford an action; and a grouping effect between objects which form action-related pairs.

Tagging partially reconstructed objects with jet substructure

DOE PAGES

Freytsis, Marat; Volansky, Tomer; Walsh, Jonathan R.

2016-08-24

Here, we present a new tagger which aims at identifying partially reconstructed objects, in which only some of the constituents are collected in a single jet. As an example, we also focus on top decays in which either part of the hadronically decaying W or the b jet is soft or falls outside of the top jet cone. Furthermore, we construct an observable to identify remnant substructure from the decay and employ aggressive jet grooming to reject QCD backgrounds. The tagger is complementary to existing ones and works well in the intermediate boost regime where jet substructure techniques usually fail.more » It is anticipated that a similar tagger can be used to identify non-QCD hadronic jets, such as those expected from hidden valleys.« less

Diffraction gratings used as identifying markers

DOEpatents

Deason, V.A.; Ward, M.B.

1991-03-26

A finely detailed diffraction grating is applied to an object as an identifier or tag which is unambiguous, difficult to duplicate, or remove and transfer to another item, and can be read and compared with prior readings with relative ease. The exact pattern of the diffraction grating is mapped by diffraction moire techniques and recorded for comparison with future readings of the same grating. 7 figures.

Diffraction gratings used as identifying markers

DOEpatents

Deason, Vance A.; Ward, Michael B.

1991-01-01

A finely detailed defraction grating is applied to an object as an identifier or tag which is unambiguous, difficult to duplicate, or remove and transfer to another item, and can be read and compared with prior readings with relative ease. The exact pattern of the defraction grating is mapped by diffraction moire techniques and recorded for comparison with future readings of the same grating.

Objective assessment of attention in delirium: a narrative review.

PubMed

Tieges, Zoë; Brown, Laura J E; MacLullich, Alasdair M J

2014-12-01

Inattention is a core feature of delirium, and valid assessment of attention is central to diagnosis. Methods of measuring attention in delirium can be divided into two broad categories: (i) objective neuropsychological testing; and (ii) subjective grading of behaviour during interview and clinical examination. Here, we review and critically evaluate studies of objective neuropsychological testing of attention in delirium. We examine the implications of these studies for delirium detection and monitoring in clinical practice and research, and how these studies inform understanding of the nature of attentional deficits in delirium. Searches of MEDLINE and ISI Web of Knowledge databases were performed to identify studies in which objective tests of attention had been administered to patients with delirium, who had been diagnosed using DSM or ICD criteria. Sixteen publications were identified. The attention tests administered in these studies were grouped into the following categories: measures of attention span, vigilance tests, other pen-and-paper tests (e.g. Trail Making Test) and computerised tests of speeded reaction, vigilance and sustained attention. Patients with delirium showed deficits on all tasks, although most tasks were not considered pure measures of attention. Five papers provided data on differential diagnosis from dementia. Cancellation tests, spatial span tests and computerised tests of sustained attention discriminated delirium from dementia. Five studies presented reliability or validity statistics. The existing evidence base on objective assessment of attention in delirium is small. Objective testing of attention is underdeveloped but shows considerable promise in clinical practice and research. Copyright © 2014 John Wiley & Sons, Ltd.

Digital Equivalent Data System for XRF Labeling of Objects

NASA Technical Reports Server (NTRS)

Schramm, Harry F.; Kaiser, Bruce

2005-01-01

A digital equivalent data system (DEDS) is a system for identifying objects by means of the x-ray fluorescence (XRF) spectra of labeling elements that are encased in or deposited on the objects. As such, a DEDS is a revolutionary new major subsystem of an XRF system. A DEDS embodies the means for converting the spectral data output of an XRF scanner to an ASCII alphanumeric or barcode label that can be used to identify (or verify the assumed or apparent identity of) an XRF-scanned object. A typical XRF spectrum of interest contains peaks at photon energies associated with specific elements on the Periodic Table (see figure). The height of each spectral peak above the local background spectral intensity is proportional to the relative abundance of the corresponding element. Alphanumeric values are assigned to the relative abundances of the elements. Hence, if an object contained labeling elements in suitably chosen proportions, an alphanumeric representation of the object could be extracted from its XRF spectrum. The mixture of labeling elements and for reading the XRF spectrum would be compatible with one of the labeling conventions now used for bar codes and binary matrix patterns (essentially, two-dimensional bar codes that resemble checkerboards). A further benefit of such compatibility is that it would enable the conversion of the XRF spectral output to a bar or matrix-coded label, if needed. In short, a process previously used only for material composition analysis has been reapplied to the world of identification. This new level of verification is now being used for "authentication."

Objectives and Contents of the Educational Activity Oriented Toward the Small Child.

ERIC Educational Resources Information Center

Walczyna, Jadwiga

This paper emphasizes the importance of educational activities for small children and discusses the issues and problems associated with choice of educational objectives and activity content. Three factors which influence the formation of educational objectives are identified: (1) tradition, (2) specific character of socio-economic conditions in…

The construction of learning objects on communicable diseases for community health agents.

PubMed

Pacheco, Kátia Cilene Ferreira; Azambuja, Marcelo Schenk de; Bonamigo, Andrea Wander

2018-06-07

To describe the creation of a learning object about communicable diseases and their identification, monitoring, and prevention for community health agents. The qualitative, exploratory, case study conducted in the North District Management Zone - Baltazar of the Universidade Federal de Ciências da Saúde de Porto Alegre, from October to January 2015 2016. The study had 58 participants and consisted of the stages field research, Bardin's content analysis, and design of the learning object. The profile of the professionals working in the location was established. These agents identified the most commonly found diseases and stressed their needs in relation to a technological resource. The identified needs were considered to define the content and structure the learning object. The learning object is an alternative method for sharing knowledge on communicable diseases. The tool allows the combination of technology with teaching, which makes the learning process and the work of the community health agents more rewarding and productive.

Early object relations into new objects.

PubMed

Downey, T W

2001-01-01

dramatic change that has hitherto been poorly identified and conceptualized. In child analysis, play is the medium for picking the lock of both arrested maturation and stultified development. Realizing that should permit the child analyst to engage more freely with the child in their own style of play without being overly concerned about the presence or absence of relational dynamic material. Non-dynamic play may not usually be defensive play, though it has often been misinterpreted as such. It may represent activity supporting renewed maturation--practice play in the service of memory, motility, or small or large motor function rather than in the service of the playful, repetitive externalization of threatening introjects. Dynamic play highlights the stagnant or emerging functions of the ego with regard to defense and affect management, which may then be interpreted using the play as key or using words as key to unlock the troubled relationship that is being dramatized. The analyst remains in a non-defensive stance, assigned by the analysand as audience or benign participant. Similarly, in adult analyses some individuals come pre-programmed not so much for interpretation as to discover the analyst as new object. They are in search of near psychobiological maturational closure on an object, already constituted in fantasy, that is respectful, attentive, objective, interested, and sometimes enlightening in their attempts at analytic understanding and developmental homeostasis. This phenomenon is akin to love at first sight, though without the flagrant libidinal romantic element. It occurs as the analytic narrative unfolds and the patient comes to a new sense of self, often around some developmental role or mix of roles, such as spouse, lover, mother, student, sibling, or worker. The point is that playing on the black and white keys of development and maturation leads to the appreciation of a psychoanalytic instrument that is at once more complex and yet easier to get music

Identifying Future Unexpected Survivors: A Retrospective Cohort Study of Fatal Injury Patterns in Victims of Improvised Explosive Devices

DTIC Science & Technology

2013-01-01

e003130. doi:10.1136/ bmjopen-2013-003130 ▸ Prepublication history for this paper is available online . To view these files please visit the journal... online (http://dx.doi.org/10.1136/ bmjopen-2013-003130). Received 26 April 2013 Revised 21 June 2013 Accepted 24 June 2013 For numbered affiliations see...harass and often incorporating military stores ’.2 IEDs have been shown to generate a different injury profile compared to con- ventional munitions, and

Effects of Near-Term Sea-Level Rise on Coastal Infrastructure

DTIC Science & Technology

2013-03-01

methodology is more objective, and more robust, than the standard methods of counting overwash sand layers or identifying marine microfossils in the...duration thresholds on Atlantic tropical cyclone counts , J. Climate, 23, 2508-2519, doi:10.1175/2009JCLI3034.1. Lane, P., Donnelly, J.P., Woodruff...Holocene Climate in the Northern Great Plains Inferred from Sediment Stratigraphy, Stable Isotopes, Carbonate Geochemistry, Diatoms, and Pollen at Moon

Implementing RDA Data Citation Recommendations: Case Study in South Africa

NASA Astrophysics Data System (ADS)

Hugo, Wim

2016-04-01

SAEON operates a shared research data infrastructure for its own data sets and for clients and end users in the Earth and Environmental Sciences domain. SAEON has a license to issue Digital Object Identifiers via DataCite on behalf of third parties, and have recently concluded development work to make a universal data deposit, description, and DOI minting facility available. This facility will be used to develop a number of end user gateways, including DataCite South Africa (in collaboration with National Research Foundation and addressing all grant-funded research in the country), DIRISA (Data-intensive Research Infrastructure for South Africa - in collaboration with Meraka Institute and Department of Science and Technology), and SASDI (South African Spatial Data Infrastructure). The RDA recently published Data Citation Recommendations [1], and this was used as a basis for specification of Digital Object Identifier implementation, raising two significant challenges: 1. Synchronisation of frequently harvested meta-data sets where version management practice did not align with the RDA recommendations, and 2. Handling sub-sets of and queries on large, continuously updated data sets. In the first case, we have developed a set of tests that determine the logical course of action when discrepancies are found during synchronization, and we have incorporated these into meta-data harvester configurations. Additionally, we have developed a state diagram and attendant workflow for meta-data that includes problem states emanating from DOI management, reporting services for data depositors, and feedback to end users in respect of synchronisation issues. In the second case, in the absence of firm guidelines from DataCite, we are seeking community consensus and feedback on an approach that caches all queries performed and subsets derived from data, and provide these with anchor-style extensions linked to the dataset's original DOI. This allows extended DOIs to resolve to a meta

Application of a single-objective, hybrid genetic algorithm approach to pharmacokinetic model building.

PubMed

Sherer, Eric A; Sale, Mark E; Pollock, Bruce G; Belani, Chandra P; Egorin, Merrill J; Ivy, Percy S; Lieberman, Jeffrey A; Manuck, Stephen B; Marder, Stephen R; Muldoon, Matthew F; Scher, Howard I; Solit, David B; Bies, Robert R

2012-08-01

A limitation in traditional stepwise population pharmacokinetic model building is the difficulty in handling interactions between model components. To address this issue, a method was previously introduced which couples NONMEM parameter estimation and model fitness evaluation to a single-objective, hybrid genetic algorithm for global optimization of the model structure. In this study, the generalizability of this approach for pharmacokinetic model building is evaluated by comparing (1) correct and spurious covariate relationships in a simulated dataset resulting from automated stepwise covariate modeling, Lasso methods, and single-objective hybrid genetic algorithm approaches to covariate identification and (2) information criteria values, model structures, convergence, and model parameter values resulting from manual stepwise versus single-objective, hybrid genetic algorithm approaches to model building for seven compounds. Both manual stepwise and single-objective, hybrid genetic algorithm approaches to model building were applied, blinded to the results of the other approach, for selection of the compartment structure as well as inclusion and model form of inter-individual and inter-occasion variability, residual error, and covariates from a common set of model options. For the simulated dataset, stepwise covariate modeling identified three of four true covariates and two spurious covariates; Lasso identified two of four true and 0 spurious covariates; and the single-objective, hybrid genetic algorithm identified three of four true covariates and one spurious covariate. For the clinical datasets, the Akaike information criterion was a median of 22.3 points lower (range of 470.5 point decrease to 0.1 point decrease) for the best single-objective hybrid genetic-algorithm candidate model versus the final manual stepwise model: the Akaike information criterion was lower by greater than 10 points for four compounds and differed by less than 10 points for three

Systems and methods for maintaining multiple objects within a camera field-of-view

DOEpatents

Gans, Nicholas R.; Dixon, Warren

2016-03-15

In one embodiment, a system and method for maintaining objects within a camera field of view include identifying constraints to be enforced, each constraint relating to an attribute of the viewed objects, identifying a priority rank for the constraints such that more important constraints have a higher priority that less important constraints, and determining the set of solutions that satisfy the constraints relative to the order of their priority rank such that solutions that satisfy lower ranking constraints are only considered viable if they also satisfy any higher ranking constraints, each solution providing an indication as to how to control the camera to maintain the objects within the camera field of view.

Detecting objects in radiographs for homeland security

NASA Astrophysics Data System (ADS)

Prasad, Lakshman; Snyder, Hans

2005-05-01

We present a general scheme for segmenting a radiographic image into polygons that correspond to visual features. This decomposition provides a vectorized representation that is a high-level description of the image. The polygons correspond to objects or object parts present in the image. This characterization of radiographs allows the direct application of several shape recognition algorithms to identify objects. In this paper we describe the use of constrained Delaunay triangulations as a uniform foundational tool to achieve multiple visual tasks, namely image segmentation, shape decomposition, and parts-based shape matching. Shape decomposition yields parts that serve as tokens representing local shape characteristics. Parts-based shape matching enables the recognition of objects in the presence of occlusions, which commonly occur in radiographs. The polygonal representation of image features affords the efficient design and application of sophisticated geometric filtering methods to detect large-scale structural properties of objects in images. Finally, the representation of radiographs via polygons results in significant reduction of image file sizes and permits the scalable graphical representation of images, along with annotations of detected objects, in the SVG (scalable vector graphics) format that is proposed by the world wide web consortium (W3C). This is a textual representation that can be compressed and encrypted for efficient and secure transmission of information over wireless channels and on the Internet. In particular, our methods described here provide an algorithmic framework for developing image analysis tools for screening cargo at ports of entry for homeland security.

A superluminous object in the Large Cloud of Magellan

NASA Astrophysics Data System (ADS)

Mathis, J. S.; Savage, B. D.; Cassinelli, J. P.

1984-08-01

The superluminous object R136a of the nebula 30 Dor in the Large Cloud of Magellan is characterized, summarizing the results of recent optical and (IUE) UV observations. Photographs, spectra, and diagrams are provided; and the techniques used to determine the parameters of the object are explained. The UV spectra exhibit a typical P Cygni profile like that of O-type stars, but R136a is much brighter (5 x 10 to the 7th solar luminosity). Speckle interferometry has identified a main component and two fainter objects at distances of 0.5 and 0.1 arcsec. The main component R136a1 is probably either a very massive single star (400-1000 solar mass) or a tight cluster of stars of known types. Evidence for the existence of other similar objects is reviewed.

The impact of Life Science Identifier on informatics data.

PubMed

Martin, Sean; Hohman, Moses M; Liefeld, Ted

2005-11-15

Since the Life Science Identifier (LSID) data identification and access standard made its official debut in late 2004, several organizations have begun to use LSIDs to simplify the methods used to uniquely name, reference and retrieve distributed data objects and concepts. In this review, the authors build on introductory work that describes the LSID standard by documenting how five early adopters have incorporated the standard into their technology infrastructure and by outlining several common misconceptions and difficulties related to LSID use, including the impact of the byte identity requirement for LSID-identified objects and the opacity recommendation for use of the LSID syntax. The review describes several shortcomings of the LSID standard, such as the lack of a specific metadata standard, along with solutions that could be addressed in future revisions of the specification.

The Dynamic Multisensory Engram: Neural Circuitry Underlying Crossmodal Object Recognition in Rats Changes with the Nature of Object Experience.

PubMed

Jacklin, Derek L; Cloke, Jacob M; Potvin, Alphonse; Garrett, Inara; Winters, Boyer D

2016-01-27

Rats, humans, and monkeys demonstrate robust crossmodal object recognition (CMOR), identifying objects across sensory modalities. We have shown that rats' performance of a spontaneous tactile-to-visual CMOR task requires functional integration of perirhinal (PRh) and posterior parietal (PPC) cortices, which seemingly provide visual and tactile object feature processing, respectively. However, research with primates has suggested that PRh is sufficient for multisensory object representation. We tested this hypothesis in rats using a modification of the CMOR task in which multimodal preexposure to the to-be-remembered objects significantly facilitates performance. In the original CMOR task, with no preexposure, reversible lesions of PRh or PPC produced patterns of impairment consistent with modality-specific contributions. Conversely, in the CMOR task with preexposure, PPC lesions had no effect, whereas PRh involvement was robust, proving necessary for phases of the task that did not require PRh activity when rats did not have preexposure; this pattern was supported by results from c-fos imaging. We suggest that multimodal preexposure alters the circuitry responsible for object recognition, in this case obviating the need for PPC contributions and expanding PRh involvement, consistent with the polymodal nature of PRh connections and results from primates indicating a key role for PRh in multisensory object representation. These findings have significant implications for our understanding of multisensory information processing, suggesting that the nature of an individual's past experience with an object strongly determines the brain circuitry involved in representing that object's multisensory features in memory. The ability to integrate information from multiple sensory modalities is crucial to the survival of organisms living in complex environments. Appropriate responses to behaviorally relevant objects are informed by integration of multisensory object features

STS-87 M.S. Takao Doi, Ph.D., of NASDA after landing

NASA Technical Reports Server (NTRS)

1997-01-01

STS-87 Mission Specialist Takao Doi, Ph.D., of the National Space Development Agency (NASDA) of Japan greets a NASDA official shortly after the orbiter Columbia returned to KSC, touching down on Runway 33 at KSC's Shuttle Landing Facility. STS-87 concluded its mission with a main gear touchdown at 7:20:04 a.m. EST Dec. 5, drawing the 15-day, 16-hour and 34-minute-long mission of 6.5 million miles to a close. Also onboard the orbiter were Commander Kevin Kregel; Pilot Steven Lindsey; Mission Specialists Winston Scott and Kalpana Chawla, Ph.D.; and Payload Specialist Leonid Kadenyuk of the National Space Agency of Ukraine. During the 88th Space Shuttle mission, the crew performed experiments on the United States Microgravity Payload-4 and pollinated plants as part of the Collaborative Ukrainian Experiment. This was the 12th landing for Columbia at KSC and the 41st KSC landing in the history of the Space Shuttle program.

Distributed design approach in persistent identifiers systems

NASA Astrophysics Data System (ADS)

Golodoniuc, Pavel; Car, Nicholas; Klump, Jens

2017-04-01

The need to identify both digital and physical objects is ubiquitous in our society. Past and present persistent identifier (PID) systems, of which there is a great variety in terms of technical and social implementations, have evolved with the advent of the Internet, which has allowed for globally unique and globally resolvable identifiers. PID systems have catered for identifier uniqueness, integrity, persistence, and trustworthiness, regardless of the identifier's application domain, the scope of which has expanded significantly in the past two decades. Since many PID systems have been largely conceived and developed by small communities, or even a single organisation, they have faced challenges in gaining widespread adoption and, most importantly, the ability to survive change of technology. This has left a legacy of identifiers that still exist and are being used but which have lost their resolution service. We believe that one of the causes of once successful PID systems fading is their reliance on a centralised technical infrastructure or a governing authority. Golodoniuc et al. (2016) proposed an approach to the development of PID systems that combines the use of (a) the Handle system, as a distributed system for the registration and first-degree resolution of persistent identifiers, and (b) the PID Service (Golodoniuc et al., 2015), to enable fine-grained resolution to different information object representations. The proposed approach solved the problem of guaranteed first-degree resolution of identifiers, but left fine-grained resolution and information delivery under the control of a single authoritative source, posing risk to the long-term availability of information resources. Herein, we develop these approaches further and explore the potential of large-scale decentralisation at all levels: (i) persistent identifiers and information resources registration; (ii) identifier resolution; and (iii) data delivery. To achieve large-scale decentralisation

Identifying synergies between water resource protection and farm business objectives: the role of soil management

NASA Astrophysics Data System (ADS)

Stoate, Chris

2017-04-01

We use a 3,000 ha BACI experiment on clay soils in central England as a focus for exploring synergies between Water Framework Directive targets for water quality (sediment, nutrients and pesticides) and crop production objectives of farm businesses. Based on base of catchment annual sediment loads, we estimate annual soil loss from farmland to be in the order of 0.3 - 0.6 tonnes per hectare. This has impacts on aquatic ecology, reservoir storage capacity and downstream flood risk through sedimentation of drainage channels. Soil loss is relatively low in a European context but reflects poorly functioning soils with high runoff risk, and poor crop performance due to compaction, low organic matter, waterlogging, and competition from the grass weed, blackgrass (Alopecuris alopoides). We use a range of mechanisms to increase farmers' awareness, understanding and motivation for improving soil management to meet multiple public and private benefits of soil function and present results for soil organic matter testing, earthworm surveying, and horizontal and vertical soil compaction mapping.

Visual attention is required for multiple object tracking.

PubMed

Tran, Annie; Hoffman, James E

2016-12-01

In the multiple object tracking task, participants attempt to keep track of a moving set of target objects embedded in an identical set of moving distractors. Depending on several display parameters, observers are usually only able to accurately track 3 to 4 objects. Various proposals attribute this limit to a fixed number of discrete indexes (Pylyshyn, 1989), limits in visual attention (Cavanagh & Alvarez, 2005), or "architectural limits" in visual cortical areas (Franconeri, 2013). The present set of experiments examined the specific role of visual attention in tracking using a dual-task methodology in which participants tracked objects while identifying letter probes appearing on the tracked objects and distractors. As predicted by the visual attention model, probe identification was faster and/or more accurate when probes appeared on tracked objects. This was the case even when probes were more than twice as likely to appear on distractors suggesting that some minimum amount of attention is required to maintain accurate tracking performance. When the need to protect tracking accuracy was relaxed, participants were able to allocate more attention to distractors when probes were likely to appear there but only at the expense of large reductions in tracking accuracy. A final experiment showed that people attend to tracked objects even when letters appearing on them are task-irrelevant, suggesting that allocation of attention to tracked objects is an obligatory process. These results support the claim that visual attention is required for tracking objects. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

The efficacy of wire and glue hair snares in identifying mesocarnivores

Treesearch

William J. Zielinski; Fredrick V. Schlexer; Kristine L. Pilgrim; Michael K. Schwartz

2006-01-01

Track plates and cameras are proven methods for detecting and identifying fishers (Martes pennant) and other mesocarnivores. But these methods are inadequate to achieve demographic and population-monitoring objectives that require identifying sex and individuals. Although noninvasive collection of biological material for genetic analysis (i.e.,...

Identifying web usage behavior of bank customers

NASA Astrophysics Data System (ADS)

Araya, Sandro; Silva, Mariano; Weber, Richard

2002-03-01

The bank Banco Credito e Inversiones (BCI) started its virtual bank in 1996 and its registered customers perform currently more than 10,000 Internet transactions daily, which typically cause les than 10% of traditional transaction costs. Since most of the customers are still not registered for online banking, one of the goals of the virtual bank is to increase then umber of registered customers. Objective of the presented work was to identify customers who are likely to perform online banking but still do not use this medium for their transactions. This objective has been reached by determining profiles of registered customers who perform many transactions online. Based on these profiles the bank's Data Warehouse is explored for twins of these heavy users that are still not registered for online banking. We applied clustering in order to group the registered customers into five classes. One of these classes contained almost 30% of all registered customers and could clearly be identified as class of heavy users. Next a neural network assigned online customers to the previously found five classes. Applying the network trained on online customers to all the bank customers identified twins of heavy users that, however had not performed online transactions so far. A mailing to these candidates informing about the advantages of online banking doubled the number of registrations compared to previous campaigns.

Sloppy morphological tuning in identified neurons of the crustacean stomatogastric ganglion

PubMed Central

Otopalik, Adriane G; Goeritz, Marie L; Sutton, Alexander C; Brookings, Ted; Guerini, Cosmo; Marder, Eve

2017-01-01

Neuronal physiology depends on a neuron’s ion channel composition and unique morphology. Variable ion channel compositions can produce similar neuronal physiologies across animals. Less is known regarding the morphological precision required to produce reliable neuronal physiology. Theoretical studies suggest that moraphology is tightly tuned to minimize wiring and conduction delay of synaptic events. We utilize high-resolution confocal microscopy and custom computational tools to characterize the morphologies of four neuron types in the stomatogastric ganglion (STG) of the crab Cancer borealis. Macroscopic branching patterns and fine cable properties are variable within and across neuron types. We compare these neuronal structures to synthetic minimal spanning neurite trees constrained by a wiring cost equation and find that STG neurons do not adhere to prevailing hypotheses regarding wiring optimization principles. In this highly modulated and oscillating circuit, neuronal structures appear to be governed by a space-filling mechanism that outweighs the cost of inefficient wiring. DOI: http://dx.doi.org/10.7554/eLife.22352.001 PMID:28177286

In Preparation of the Nationwide Dissemination of the School-Based Obesity Prevention Program DOiT: Stepwise Development Applying the Intervention Mapping Protocol

ERIC Educational Resources Information Center

van Nassau, Femke; Singh, Amika S.; van Mechelen, Willem; Brug, Johannes; Chin A. Paw, Mai J. M.