On the intrinsic spectrum of PKS 2155-304 from the H.E.S.S. 2003 data.

NASA Astrophysics Data System (ADS)

Costamante, L.; Aharonian, F.; Benbow, W.; Horns, D.; Reimer, A.; Reimer, O.; Rowell, G.; H.E.S.S. Collaboration

2004-08-01

In 2003, PKS 2155-304 (z=0.116) has been significantly detected by H.E.S.S. ( 44sigma) at TeV energies, with an average spectrum of Γ =3.3. Due to absorption by the Extragalactic Background Light (EBL), the intrinsic spectrum is heavily modified both in shape and intensity. To correct for this effect, and see where could be the Inverse Compton (IC) peak of the SED, we used 3 EBL models (representatives of 3 different flux levels for the stellar peak component). The resulting TeV spectrum has a peak around 1 TeV for stellar peak fluxes above the Primack (2001) calculation, while the spectrum is steeper than 2 (thus locating the IC peak <200 GeV) for fluxes below. With bulk Lorentz factors δ =20-30 (typically used for this object), in the first case the IC peak is in the Klein-Nishina transition region, while in the other case it is in the Thomson regime, and in agreement with the commonly fitted source parameters (e.g. Tavecchio et al. 1998). The constraint on δ given by transparency to 1-2 TeV photons is δ >19 (for historical SED fluxes and 2 hrs variability timescale).

Establishing the spectral turnover of blazar PKS 2155-304 as an outcome of radiative losses

NASA Astrophysics Data System (ADS)

Jagan, Sitha K.; Sahayanathan, S.; Misra, R.; Ravikumar, C. D.; Jeena, K.

2018-07-01

The broad-band optical/UV and X-ray spectra of blazars have been often modelled as synchrotron component arising from a broken power-law distribution of electrons. A broken power-law distribution is expected, since the high-energy electrons undergo radiative losses effectively. The change in the energy index should then be ≈1 and corresponds to a spectral index difference of 0.5. However, one of the long outstanding problems has been that the observed index change is significantly different. On the other hand, recent high-quality observations of blazars suggest that their local spectra may not be a power law, instead have a slight curvature and often represented by a log-parabola model. Using XMM-Newtonobservations spanning over 12 yr for the BL Lac PKS 2155-304, we show that the optical/UV and X-ray spectra can be well represented by a broken log-parabola model. Further, we show that such a spectrum can indicate the energy dependence of the electron escape time-scale from the main acceleration zone. This novel approach, besides addressing the observed difference in the photon spectral indices, also tries to explain the spectral turn over in far-UV/soft X-rays as a result of the radiative losses.

Establishing the spectral turnover of blazar PKS 2155-304 as an outcome of radiative losses

NASA Astrophysics Data System (ADS)

Jagan, Sitha K.; Sahayanathan, S.; Misra, R.; Ravikumar, C. D.; Jeena, K.

2018-06-01

The broad-band optical/UV and X-ray spectra of blazars have been often modelled as synchrotron component arising from a broken power-law distribution of electrons. A broken power-law distribution is expected, since the high energy electrons undergo radiative losses effectively. The change in the energy index should then be ≈1 and corresponds to a spectral index difference of 0.5. However, one of the long outstanding problems has been that the observed index change is significantly different. On the other hand, recent high quality observations of blazars suggest that their local spectra may not be a power-law, instead have a slight curvature and often represented by a log parabola model. Using XMM-Newton observations spanning over 12 years for the BL Lac PKS 2155-304, we show that the optical/UV and X-ray spectra can be well represented by a broken log parabola model. Further, we show that such a spectrum can indicate the energy dependence of the electron escape time-scale from the main acceleration zone. This novel approach, besides addressing the observed difference in the photon spectral indices, also tries to explain the spectral turn over in far-UV/soft X-rays as a result of the radiative losses.

Characterizing the γ-ray long-term variability of PKS 2155-304 with H.E.S.S. and Fermi-LAT

NASA Astrophysics Data System (ADS)

H.E.S.S. Collaboration; Abdalla, H.; Abramowski, A.; Aharonian, F.; Ait Benkhali, F.; Akhperjanian, A. G.; Andersson, T.; Angüner, E. O.; Arrieta, M.; Aubert, P.; Backes, M.; Balzer, A.; Barnard, M.; Becherini, Y.; Becker Tjus, J.; Berge, D.; Bernhard, S.; Bernlöhr, K.; Blackwell, R.; Böttcher, M.; Boisson, C.; Bolmont, J.; Bordas, P.; Bregeon, J.; Brun, F.; Brun, P.; Bryan, M.; Bulik, T.; Capasso, M.; Carr, J.; Casanova, S.; Cerruti, M.; Chakraborty, N.; Chalme-Calvet, R.; Chaves, R. C. G.; Chen, A.; Chevalier, J.; Chrétien, M.; Colafrancesco, S.; Cologna, G.; Condon, B.; Conrad, J.; Cui, Y.; Davids, I. D.; Decock, J.; Degrange, B.; Deil, C.; Devin, J.; deWilt, P.; Dirson, L.; Djannati-Ataï, A.; Domainko, W.; Donath, A.; Drury, L. O.'C.; Dubus, G.; Dutson, K.; Dyks, J.; Edwards, T.; Egberts, K.; Eger, P.; Ernenwein, J.-P.; Eschbach, S.; Farnier, C.; Fegan, S.; Fernandes, M. V.; Fiasson, A.; Fontaine, G.; Förster, A.; Funk, S.; Füßling, M.; Gabici, S.; Gajdus, M.; Gallant, Y. A.; Garrigoux, T.; Giavitto, G.; Giebels, B.; Glicenstein, J. F.; Gottschall, D.; Goyal, A.; Grondin, M.-H.; Hadasch, D.; Hahn, J.; Haupt, M.; Hawkes, J.; Heinzelmann, G.; Henri, G.; Hermann, G.; Hervet, O.; Hinton, J. A.; Hofmann, W.; Hoischen, C.; Holler, M.; Horns, D.; Ivascenko, A.; Jacholkowska, A.; Jamrozy, M.; Janiak, M.; Jankowsky, D.; Jankowsky, F.; Jingo, M.; Jogler, T.; Jouvin, L.; Jung-Richardt, I.; Kastendieck, M. A.; Katarzyński, K.; Katz, U.; Kerszberg, D.; Khélifi, B.; Kieffer, M.; King, J.; Klepser, S.; Klochkov, D.; Kluźniak, W.; Kolitzus, D.; Komin, Nu.; Kosack, K.; Krakau, S.; Kraus, M.; Krayzel, F.; Krüger, P. P.; Laffon, H.; Lamanna, G.; Lau, J.; Lees, J.-P.; Lefaucheur, J.; Lefranc, V.; Lemière, A.; Lemoine-Goumard, M.; Lenain, J.-P.; Leser, E.; Lohse, T.; Lorentz, M.; Liu, R.; López-Coto, R.; Lypova, I.; Marandon, V.; Marcowith, A.; Mariaud, C.; Marx, R.; Maurin, G.; Maxted, N.; Mayer, M.; Meintjes, P. J.; Meyer, M.; Mitchell, A. M. W.; Moderski, R.; Mohamed, M.; Mohrmann, L.; Morå, K.; Moulin, E.; Murach, T.; de Naurois, M.; Niederwanger, F.; Niemiec, J.; Oakes, L.; O'Brien, P.; Odaka, H.; Öttl, S.; Ohm, S.; Ostrowski, M.; Oya, I.; Padovani, M.; Panter, M.; Parsons, R. D.; Pekeur, N. W.; Pelletier, G.; Perennes, C.; Petrucci, P.-O.; Peyaud, B.; Piel, Q.; Pita, S.; Poon, H.; Prokhorov, D.; Prokoph, H.; Pühlhofer, G.; Punch, M.; Quirrenbach, A.; Raab, S.; Reimer, A.; Reimer, O.; Renaud, M.; de los Reyes, R.; Rieger, F.; Romoli, C.; Rosier-Lees, S.; Rowell, G.; Rudak, B.; Rulten, C. B.; Sahakian, V.; Salek, D.; Sanchez, D. A.; Santangelo, A.; Sasaki, M.; Schlickeiser, R.; Schüssler, F.; Schulz, A.; Schwanke, U.; Schwemmer, S.; Settimo, M.; Seyffert, A. S.; Shafi, N.; Shilon, I.; Simoni, R.; Sol, H.; Spanier, F.; Spengler, G.; Spies, F.; Stawarz, Ł.; Steenkamp, R.; Stegmann, C.; Stinzing, F.; Stycz, K.; Sushch, I.; Tavernet, J.-P.; Tavernier, T.; Taylor, A. M.; Terrier, R.; Tibaldo, L.; Tiziani, D.; Tluczykont, M.; Trichard, C.; Tuffs, R.; Uchiyama, Y.; van der Walt, D. J.; van Eldik, C.; van Rensburg, C.; van Soelen, B.; Vasileiadis, G.; Veh, J.; Venter, C.; Viana, A.; Vincent, P.; Vink, J.; Voisin, F.; Völk, H. J.; Vuillaume, T.; Wadiasingh, Z.; Wagner, S. J.; Wagner, P.; Wagner, R. M.; White, R.; Wierzcholska, A.; Willmann, P.; Wörnlein, A.; Wouters, D.; Yang, R.; Zabalza, V.; Zaborov, D.; Zacharias, M.; Zdziarski, A. A.; Zech, A.; Zefi, F.; Ziegler, A.; Żywucka, N.

2017-02-01

Studying the temporal variability of BL Lac objects at the highest energies provides unique insights into the extreme physical processes occurring in relativistic jets and in the vicinity of super-massive black holes. To this end, the long-term variability of the BL Lac object PKS 2155-304 is analyzed in the high (HE, 100 MeV < E < 300 GeV) and very high energy (VHE, E > 200 GeV) γ-ray domain. Over the course of 9 yr of H.E.S.S. observations the VHE light curve in the quiescent state is consistent with a log-normal behavior. The VHE variability in this state is well described by flicker noise (power-spectral-density index ) on timescales larger than one day. An analysis of 5.5 yr of HE Fermi-LAT data gives consistent results (, on timescales larger than 10 days) compatible with the VHE findings. The HE and VHE power spectral densities show a scale invariance across the probed time ranges. A direct linear correlation between the VHE and HE fluxes could neither be excluded nor firmly established. These long-term-variability properties are discussed and compared to the red noise behavior (β 2) seen on shorter timescales during VHE-flaring states. The difference in power spectral noise behavior at VHE energies during quiescent and flaring states provides evidence that these states are influenced by different physical processes, while the compatibility of the HE and VHE long-term results is suggestive of a common physical link as it might be introduced by an underlying jet-disk connection.

First NuSTAR Observations of the BL Lac-Type Blazar PKS 2155-304: Constraints on the Jet Content and Distribution of Radiating Particles

NASA Technical Reports Server (NTRS)

Madejski, G. M.; Nalewajko, K.; Madsen, K. K.; Chiang, J.; Balokovic, M.; Paneque, D.; Furniss, A. K.; Hayashida, M.; Urry, C. M.; Sikora, M.;

First NuSTAR Observations of the BL Lac-type Blazar PKS 2155-304: Constraints on the Jet Content and Distribution of Radiating Particles

NASA Astrophysics Data System (ADS)

Madejski, G. M.; Nalewajko, K.; Madsen, K. K.; Chiang, J.; Baloković, M.; Paneque, D.; Furniss, A. K.; Hayashida, M.; Urry, C. M.; Sikora, M.; Ajello, M.; Blandford, R. D.; Harrison, F. A.; Sanchez, D.; Giebels, B.; Stern, D.; Alexander, D. M.; Barret, D.; Boggs, S. E.; Christensen, F. E.; Craig, W. W.; Forster, K.; Giommi, P.; Grefenstette, B.; Hailey, C.; Hornstrup, A.; Kitaguchi, T.; Koglin, J. E.; Mao, P. H.; Miyasaka, H.; Mori, K.; Perri, M.; Pivovaroff, M. J.; Puccetti, S.; Rana, V.; Westergaard, N. J.; Zhang, W. W.; Zoglauer, A.

2016-11-01

We report the first hard X-ray observations with NuSTAR of the BL Lac-type blazar PKS 2155-304, augmented with soft X-ray data from XMM-Newton and γ-ray data from the Fermi Large Area Telescope, obtained in 2013 April when the source was in a very low flux state. A joint NuSTAR and XMM spectrum, covering the energy range 0.5-60 keV, is best described by a model consisting of a log-parabola component with curvature β ={0.3}-0.1+0.2 and a (local) photon index 3.04 ± 0.15 at photon energy of 2 keV, and a hard power-law tail with photon index 2.2 ± 0.4. The hard X-ray tail can be smoothly joined to the quasi-simultaneous γ-ray spectrum by a synchrotron self-Compton component produced by an electron distribution with index p = 2.2. Assuming that the power-law electron distribution extends down to γ min = 1 and that there is one proton per electron, an unrealistically high total jet power of L p ˜ 1047 erg s-1 is inferred. This can be reduced by two orders of magnitude either by considering a significant presence of electron-positron pairs with lepton-to-proton ratio {n}{{e}+{{e}}-}/{n}{{p}}˜ 30, or by introducing an additional, low-energy break in the electron energy distribution at the electron Lorentz factor γ br1 ˜ 100. In either case, the jet composition is expected to be strongly matter-dominated.

Upper limits from hard X-ray observations of five BL Lacertae objects

NASA Technical Reports Server (NTRS)

Bezler, M.; Gruber, D. E.; Rothschild, R. E.

1988-01-01

Results are presented from hard X-ray observations of the five brightest X-ray BL Lacertae objects: PKS 0548-322, Mrk 421 (=1101+384), 2A 1219+305, Mrk 501 (=1652+398), and PKS 2155-304. The observations covered the energy range 15-165 keV from August 1977 to December 1978. The results are compared with previous studies.

First NuSTAR observations of the BL Lac - type blazar PKS 2155-304: constraints on the jet content and distribution of radiating particles

NASA Astrophysics Data System (ADS)

Madejski, Grzegorz; Nalewajko, Krzysztof; Madsen, Kristin; Chiang, James; Balokovic, Mislav; Paneque, David; Furniss, Amy; NuSTAR Team

2017-01-01

Current scenarios for emission mechanisms operating in relativistic jets in AGN involve synchrotron emission for the radio through UV spectrum, and inverse Compton for hard X-rays through γ-rays, but the particle content of relativistic jets - whether they are dominated by proton-electron, or e +/e- plasma - has not been established. Our first hard X-ray observations with NuSTAR of the BL Lac type blazar PKS 2155-304, augmented by XMM-Newton data, reveal the 0.5-60 keV spectrum as best-described by a soft power law component dominating below 10 keV (photon index of 3 at 2 keV), and a hard power-law tail (index 2), dominating in the 20-60 keV range. The hard X-ray tail can be smoothly joined to the quasi-simultaneous Fermi/LAT γ-ray spectrum by a synchrotron self-Compton component produced by an electron distribution with index p =2.2. The jet content needs to (globally) obey charge neutrality; assuming that the power-law electron distribution extends down to the Lorentz factor of 1, and one proton per electron, yields an unrealistically high total jet power of 1047 erg/s. This can be reduced by two orders of magnitude by considering a significant presence of e +/e- pairs with lepton-to-proton ratio of at least 30.

Chandra Discovery of a Tree in the X-Ray Forest toward PKS 2155-304: The Local Filament?

NASA Astrophysics Data System (ADS)

Nicastro, Fabrizio; Zezas, Andreas; Drake, Jeremy; Elvis, Martin; Fiore, Fabrizio; Fruscione, Antonella; Marengo, Massimo; Mathur, Smita; Bianchi, Stefano

2002-07-01

We present the first X-ray detection of resonant absorption from warm/hot local gas either in our Galaxy, or in the intergalactic space surrounding our Galaxy, along the line of sight toward the blazar PKS 2155-304. The Chandra HRCS/LETG spectrum of this z=0.116 source clearly shows, at >=5 σ level, unresolved (FWHM<=800 km s-1 at a 2 σ confidence level) O VII Kα and Ne IX Kα resonant absorption lines at 21.603+0.014-0.024 and 13.448+0.022-0.024 Å (i.e., cz=14+190-330 km s-1 in the rest frame, from the O VII Kα line). O VIII Kα and O VII Kβ from the same system are also detected at a lower significance level (i.e., ~3 σ), while upper limits are set on O VIII Kβ, Ne X Kα, and Ne IX Kβ. The Far Ultraviolet Spectroscopic Explorer spectrum of this source shows complex O VI 2s-->2p absorption at the same redshift as the X-ray system, made by at least two components: one relatively narrow (FWHM=106+/-9 km s-1) and slightly redshifted (cz=36+/-6 km s-1), and one broader (FWHM=158+/-26 km s-1) and blueshifted (cz=-135+/-14 km s-1). We demonstrate that the physical states of the UV and X-ray absorbers are hard to reconcile with a single, purely collisionally ionized, equilibrium plasma. We propose instead that the X-ray and at least the broader and blueshifted UV absorber are produced in a low-density intergalactic plasma, collapsing toward our Galaxy, consistent with the predictions of a warm-hot intergalactic medium from numerical simulations. We find that any reasonable solution requires overabundance of Ne compared to O by a factor of ~2, with respect to the solar value. We propose several scenarios to account for this observation.

Long and short term variability of seven blazars in six near-infrared/optical bands

NASA Astrophysics Data System (ADS)

Sandrinelli, A.; Covino, S.; Treves, A.

2014-02-01

Context. We present the light curves of six BL Lac objects, PKS 0537-441, PKS 0735+17, OJ 287, PKS 2005-489, PKS 2155-304, and W Comae, and of the flat spectrum radio quasar PKS 1510-089, as a part of a photometric monitoring program in the near-infrared/optical bands started in 2004. All sources are Fermi blazars. Aims: Our purpose is to investigate flux and spectral variability on short and long time scales. Systematic monitoring, independent of the activity of the source, guarantees large sample size statistics, and allows an unbiased view of different activity states on weekly or daily time scales for the whole timeframe and on nightly time scales for some epochs. Methods: Data were obtained with the REM telescope located at the ESO premises of La Silla (Chile). Light curves were gathered in the optical/near-infrared VRIJHK bands from April 2005 to June 2012. Results: Variability ≳3 mag is observed in PKS 0537-441, PKS 1510-089 and PKS 2155-304, the largest ranges spanned in the near-infrared. The color intensity plots show rather different morphologies. The spectral energy distributions in general are well fitted by a power law, with some deviations that are more apparent in low states. Some variability episodes during a night interval are well documented for PKS 0537-441 and PKS 2155-304. For the latter source the variability time scale implies a large relativistic beaming factor. Full Table 3 is only available at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/562/A79

Photometric monitoring of three BL Lacertae objects in 1993-1998

NASA Astrophysics Data System (ADS)

Bai, J. M.; Xie, G. Z.; Li, K. H.; Zhang, X.; Liu, W. W.

1999-05-01

The results of optical photometric (BVRI) monitoring of three BL Lac objects over a time interval of about four years are presented. The sources are three classical radio-selected BL Lac objects, BL Lac, OJ 287 and PKS 0735+178. During our observation OJ 287 was in the stage of a large periodic outburst which consisted of at least two peaks. Almost all the observations obtained over consecutive nights detected intranight variations. In 1995 and 1996 BL Lac kept in faint states, with fewer and smaller rapid flares and fluctuations. On the contrary, in late 1997 BL Lac was at the stage of a large outburst, accompanied with much more large amplitude rapid flares and fluctuations. PKS 0735+178 was almost at its faint end from 1994 to early 1998. Over this time interval, the intraday variations and microvariations in PKS 0735+178 were rare and the amplitude was very small, except a rapid darkening of ~ 0.4 mag on 24 January 1995. Previous work by \\cite[Webb et al. (1988);]{web88} \\cite[Wagner et al. (1996);]{wag96} \\cite[Pian et al. (1997)]{pia97} also showed the same behaviour of variability as BL Lac and PKS 0735+178 in BL Lac, S5 0716+714, PKS 2155-304, respectively. We propose that the motion of orientation of the relativistic jet in a BL Lac object be responsible for these variability behaviours. Table~1 is only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5) or via http://cdsweb.u-strasbg.fr/Abstract.html

Search for extended γ-ray emission around AGN with H.E.S.S. and Fermi-LAT

NASA Astrophysics Data System (ADS)

H. E. S. S. Collaboration; Abramowski, A.; Aharonian, F.; Ait Benkhali, F.; Akhperjanian, A. G.; Angüner, E.; Anton, G.; Backes, M.; Balenderan, S.; Balzer, A.; Barnacka, A.; Becherini, Y.; Becker Tjus, J.; Bernlöhr, K.; Birsin, E.; Bissaldi, E.; Biteau, J.; Böttcher, M.; Boisson, C.; Bolmont, J.; Bordas, P.; Brucker, J.; Brun, F.; Brun, P.; Bulik, T.; Carrigan, S.; Casanova, S.; Chadwick, P. M.; Chalme-Calvet, R.; Chaves, R. C. G.; Cheesebrough, A.; Chrétien, M.; Colafrancesco, S.; Cologna, G.; Conrad, J.; Couturier, C.; Cui, Y.; Dalton, M.; Daniel, M. K.; Davids, I. D.; Degrange, B.; Deil, C.; deWilt, P.; Dickinson, H. J.; Djannati-Atäı, A.; Domainko, W.; Drury, L. O'C.; Dubus, G.; Dutson, K.; Dyks, J.; Dyrda, M.; Edwards, T.; Egberts, K.; Eger, P.; Espigat, P.; Farnier, C.; Fegan, S.; Feinstein, F.; Fernandes, M. V.; Fernandez, D.; Fiasson, A.; Fontaine, G.; Förster, A.; Füßling, M.; Gajdus, M.; Gallant, Y. A.; Garrigoux, T.; Giavitto, G.; Giebels, B.; Glicenstein, J. F.; Grondin, M.-H.; Grudzińska, M.; Häffner, S.; Hahn, J.; Harris, J.; Heinzelmann, G.; Henri, G.; Hermann, G.; Hervet, O.; Hillert, A.; Hinton, J. A.; Hofmann, W.; Hofverberg, P.; Holler, M.; Horns, D.; Jacholkowska, A.; Jahn, C.; Jamrozy, M.; Janiak, M.; Jankowsky, F.; Jung, I.; Kastendieck, M. A.; Katarzyński, K.; Katz, U.; Kaufmann, S.; Khélifi, B.; Kieffer, M.; Klepser, S.; Klochkov, D.; Kluźniak, W.; Kneiske, T.; Kolitzus, D.; Komin, Nu.; Kosack, K.; Krakau, S.; Krayzel, F.; Krüger, P. P.; Laffon, H.; Lamanna, G.; Lefaucheur, J.; Lemie`re, A.; Lemoine-Goumard, M.; Lenain, J.-P.; Lohse, T.; Lopatin, A.; Lu, C.-C.; Marandon, V.; Marcowith, A.; Marx, R.; Maurin, G.; Maxted, N.; Mayer, M.; McComb, T. J. L.; Méhault, J.; Meintjes, P. J.; Menzler, U.; Meyer, M.; Moderski, R.; Mohamed, M.; Moulin, E.; Murach, T.; Naumann, C. L.; de Naurois, M.; Niemiec, J.; Nolan, S. J.; Oakes, L.; Odaka, H.; Ohm, S.; de Oña Wilhelmi, E.; Opitz, B.; Ostrowski, M.; Oya, I.; Panter, M.; Parsons, R. D.; Paz Arribas, M.; Pekeur, N. W.; Pelletier, G.; Perez, J.; Petrucci, P.-O.; Peyaud, B.; Pita, S.; Poon, H.; Pühlhofer, G.; Punch, M.; Quirrenbach, A.; Raab, S.; Raue, M.; Reichardt, I.; Reimer, A.; Reimer, O.; Renaud, M.; de los Reyes, R.; Rieger, F.; Rob, L.; Romoli, C.; Rosier-Lees, S.; Rowell, G.; Rudak, B.; Rulten, C. B.; Sahakian, V.; Sanchez, D. A.; Santangelo, A.; Schlickeiser, R.; Schüssler, F.; Schulz, A.; Schwanke, U.; Schwarzburg, S.; Schwemmer, S.; Sol, H.; Spengler, G.; Spies, F.; Stawarz, Ł.; Steenkamp, R.; Stegmann, C.; Stinzing, F.; Stycz, K.; Sushch, I.; Tavernet, J.-P.; Tavernier, T.; Taylor, A. M.; Terrier, R.; Tluczykont, M.; Trichard, C.; Valerius, K.; van Eldik, C.; van Soelen, B.; Vasileiadis, G.; Venter, C.; Viana, A.; Vincent, P.; Völk, H. J.; Volpe, F.; Vorster, M.; Vuillaume, T.; Wagner, S. J.; Wagner, P.; Wagner, R. M.; Ward, M.; Weidinger, M.; Weitzel, Q.; White, R.; Wierzcholska, A.; Willmann, P.; Wörnlein, A.; Wouters, D.; Yang, R.; Zabalza, V.; Zacharias, M.; Zdziarski, A. A.; Zech, A.; Zechlin, H.-S.; Malyshev, D.

2014-02-01

Context. Very-high-energy (VHE; E > 100 GeV) γ-ray emission from blazars inevitably gives rise to electron-positron pair production through the interaction of these γ-rays with the extragalactic background light (EBL). Depending on the magnetic fields in the proximity of the source, the cascade initiated from pair production can result in either an isotropic halo around an initially beamed source or a magnetically broadened cascade flux. Aims: Both extended pair-halo (PH) and magnetically broadened cascade (MBC) emission from regions surrounding the blazars 1ES 1101-232, 1ES 0229+200, and PKS 2155-304 were searched for using VHE γ-ray data taken with the High Energy Stereoscopic System (H.E.S.S.) and high-energy (HE; 100 MeV < E < 100 GeV) γ-ray data with the Fermi Large Area Telescope (LAT). Methods: By comparing the angular distributions of the reconstructed γ-ray events to the angular profiles calculated from detailed theoretical models, the presence of PH and MBC was investigated. Results: Upper limits on the extended emission around 1ES 1101-232, 1ES 0229+200, and PKS 2155-304 are found to be at a level of a few per cent of the Crab nebula flux above 1 TeV, depending on the assumed photon index of the cascade emission. Assuming strong extra-Galactic magnetic field (EGMF) values, >10-12 G, this limits the production of pair haloes developing from electromagnetic cascades. For weaker magnetic fields, in which electromagnetic cascades would result in MBCs, EGMF strengths in the range (0.3-3)× 10-15 G were excluded for PKS 2155-304 at the 99% confidence level, under the assumption of a 1 Mpc coherence length.

THE JETS OF TeV BLAZARS AT HIGHER RESOLUTION: 43 GHz AND POLARIMETRIC VLBA OBSERVATIONS FROM 2005 TO 2009

DOE Office of Scientific and Technical Information (OSTI.GOV)

Piner, B. Glenn; Pant, Niraj; Edwards, Philip G., E-mail: gpiner@whittier.ed, E-mail: Philip.Edwards@csiro.a

We present 23 new VLBA images of the six established TeV blazars Markarian 421, Markarian 501, H 1426+428, 1ES 1959+650, PKS 2155-304, and 1ES 2344+514, obtained from 2005 to 2009. Most images were obtained at 43 GHz (7 mm), and they reveal the parsec-scale structures of three of these sources (1ES 1959+650, PKS 2155-304, and 1ES 2344+514) at factors of 2-3 higher resolution than has previously been attained. These images reveal new morphological details, including a high degree of jet bending in the inner milliarcsecond in PKS 2155-304. This establishes strong apparent jet bending on VLBI scales as a commonmore » property of TeV blazars, implying viewing angles close to the line of sight. Most of the remaining images map the linear polarization structures at a lower frequency of 22 GHz (1 cm). We discuss the transverse structures of the jets as revealed by the high-frequency and polarimetric imaging. The transverse structures include significant limb brightening in Mrk 421, and 'spine-sheath' structures in the electric vector position angle and fractional polarization distributions in Mrk 421, Mrk 501, and 1ES 1959+650. We use new measured component positions to update measured apparent jet speeds, in many cases significantly reducing the statistical error over previously published results. With the increased resolution at 43 GHz, we detect new components within 0.1-0.2 mas of the core in most of these sources. No motion is apparent in these new components over the time span of our observations, and we place upper limits on the apparent speeds of the components near the core of <2c. From those limits, we conclude that {Gamma}{sub 2} < ({Gamma}{sub 1}){sup 1/2} at {approx}10{sup 5} Schwarzschild radii, where {Gamma}{sub 1} and {Gamma}{sub 2} are the bulk Lorentz factors in the TeV emitting and 43 GHz emitting regions, respectively, assuming that their velocity vectors are aligned.« less

Transparency of the Universe to VHE Gamma rays and EBL Models

NASA Astrophysics Data System (ADS)

Singh, Krishna Kumar; Sahayanathan, Sunder; Bhatt, Nilay; Tickoo, Avtar K.

2012-07-01

GeV/TeV emission spectrum coming from distant blazars is modified en route due to absorption via pair production in presence of extragalactic background (EBL) photons. Hence the knowledge of EBL spectrum from IR to optical-UV band is important to estimate the intrinsic spectra of VHE blazars. Also, this information will help in understanding the evolution of galaxies. Here we study the opacity of VHE gamma rays at different redshifts by considering different EBL models available in the literature. The optical depth values corresponding to different gamma ray energies at a given redshift, are approximated as a fifth order polynomial and a table of the coefficients at different redshifts is produced. We use these estimates to find the intrinsic VHE spectra of the FSRQ 3C279 (z=0.536) and BL Lac object PKS 2155-304 (z=0.116) corresponding to different EBL models. The inferred intrinsic VHE spectra along with the broadband data available for these sources are then modelled using one zone models involving synchrotron and inverse Compton emission mechanisms. For PKS 2155-304 we considered synchrotron and synchrotron self Compton (SSC) emission where as for 3C 279, external Compton (EC) scattering of IR photons from dusty torus is considered in addition to these emission processes. The broadband spectrum including the VHE spectra corresponding to different EBL models is fitted to obtain the parameters using chi-square minimisation. We then compare the EBL models on the basis of minimum chi-square obtained.

32 CFR 215.5 - Policies.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 32 National Defense 2 2010-07-01 2010-07-01 false Policies. 215.5 Section 215.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS EMPLOYMENT OF MILITARY RESOURCES IN THE EVENT OF CIVIL DISTURBANCES § 215.5 Policies. (a) The employment of DoD military...

The intraday variability in the radio-selected and X-ray-selected BL Lacertae objects

NASA Astrophysics Data System (ADS)

Bai, J. M.; Xie, G. Z.; Li, K. H.; Zhang, X.; Liu, W. W.

1998-10-01

Seven BL Lac objects have been photometrically observed in an effort to study the difference of optical intraday variability between the radio-selected BL Lac objects (RBLs) and X-ray-selected BL Lac objects (XBLs). The objects we observed are selected arbitrarily. They are four RBLs, PKS 0735+178, PKS 0754+101, OJ 287 and BL Lac, and three XBLs, H 0323+022, H 0548-322 and H 2154-304. During the observation all of them exhibited microvariation, and H 0323+022 and H 0548-322 sometimes showed brightness oscillation. PKS 0735+178 and BL Lac were in their faint states and not very active. It seems that RBLs do not show microvariability more frequently than XBLs. Table 2 is only available in electronic form at the CDS via anonymous ftp to cdsarc.u-strasbg.fr (130.79.128.5)

25 CFR 215.5 - Royalty rates.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 1 2013-04-01 2013-04-01 false Royalty rates. 215.5 Section 215.5 Indians BUREAU OF..., QUAPAW AGENCY § 215.5 Royalty rates. (a) In leases offered for sale at public auction under the... royalty to be computed and based upon each sale of ore or concentrates separately, the rate of royalty to...

25 CFR 215.5 - Royalty rates.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 1 2014-04-01 2014-04-01 false Royalty rates. 215.5 Section 215.5 Indians BUREAU OF..., QUAPAW AGENCY § 215.5 Royalty rates. (a) In leases offered for sale at public auction under the... royalty to be computed and based upon each sale of ore or concentrates separately, the rate of royalty to...

37 CFR 2.155 - Notice of publication.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Notice of publication. 2.155 Section 2.155 Patents, Trademarks, and Copyrights UNITED STATES PATENT AND TRADEMARK OFFICE, DEPARTMENT OF COMMERCE RULES OF PRACTICE IN TRADEMARK CASES Publication of Marks Registered Under 1905 Act § 2.155 Notice...

29 CFR 215.5 - Processing of amendments.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 2 2013-07-01 2013-07-01 false Processing of amendments. 215.5 Section 215.5 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR GUIDELINES, SECTION 5333(b), FEDERAL TRANSIT LAW § 215.5 Processing of amendments. (a) Grant modifications in the form of grant amendments will be transmitted by the...

29 CFR 215.5 - Processing of amendments.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 2 2014-07-01 2014-07-01 false Processing of amendments. 215.5 Section 215.5 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR GUIDELINES, SECTION 5333(b), FEDERAL TRANSIT LAW § 215.5 Processing of amendments. (a) Grant modifications in the form of grant amendments will be transmitted by the...

29 CFR 215.5 - Processing of amendments.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 2 2011-07-01 2011-07-01 false Processing of amendments. 215.5 Section 215.5 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR GUIDELINES, SECTION 5333(b), FEDERAL TRANSIT LAW § 215.5 Processing of amendments. (a) Grant modifications in the form of grant amendments will be transmitted by the...

29 CFR 215.5 - Processing of amendments.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 2 2010-07-01 2010-07-01 false Processing of amendments. 215.5 Section 215.5 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR GUIDELINES, SECTION 5333(b), FEDERAL TRANSIT LAW § 215.5 Processing of amendments. (a) Grant modifications in the form of grant amendments will be transmitted by the...

29 CFR 215.5 - Processing of amendments.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 2 2012-07-01 2012-07-01 false Processing of amendments. 215.5 Section 215.5 Labor Regulations Relating to Labor OFFICE OF LABOR-MANAGEMENT STANDARDS, DEPARTMENT OF LABOR GUIDELINES, SECTION 5333(b), FEDERAL TRANSIT LAW § 215.5 Processing of amendments. (a) Grant modifications in the form of grant amendments will be transmitted by the...

40 CFR 721.2155 - Alkoxyamino-alkyl-coumarin (generic).

Code of Federal Regulations, 2010 CFR

2010-07-01

...). 721.2155 Section 721.2155 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT SIGNIFICANT NEW USES OF CHEMICAL SUBSTANCES Significant New Uses for Specific Chemical Substances § 721.2155 Alkoxyamino-alkyl-coumarin (generic). (a) Chemical substance and significant new uses...

10 CFR 215.5 - Pricing and volume reports.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 3 2011-01-01 2011-01-01 false Pricing and volume reports. 215.5 Section 215.5 Energy DEPARTMENT OF ENERGY OIL COLLECTION OF FOREIGN OIL SUPPLY AGREEMENT INFORMATION § 215.5 Pricing and volume... change (including changes in the timing of collection) by the host government in official selling prices...

10 CFR 215.5 - Pricing and volume reports.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Pricing and volume reports. 215.5 Section 215.5 Energy DEPARTMENT OF ENERGY OIL COLLECTION OF FOREIGN OIL SUPPLY AGREEMENT INFORMATION § 215.5 Pricing and volume reports. To the extent not reported pursuant to § 215.3, any person lifting for export crude oil from a...

Observations of blazars with ASCA

NASA Technical Reports Server (NTRS)

Makino, F.; Edelson, R.; Fujimoto, R.; Kii, T.; Idesawa, E.; Makishima, K.; Takahashi, T.; Sasaki, K.; Kamae, T.; Kubo, H.;

Studies of BL Lacertae objects with the Einstein Observatory - The soft X-ray spectra of OJ 287 and PKS 0735+178

NASA Technical Reports Server (NTRS)

Madejski, Greg M.; Schwartz, Daniel A.

1988-01-01

Accurate, soft X-ray spectra of two BL Lac objects, OJ 287 and PKS 0735+178, are presented. The X-ray spectra are well described by a power-law model with a low-energy cutoff consistent with photoelectric absorption within the Galaxy. The best-fit values of the energy spectral index in the 0.2-4.0 keV band are 0.91 and 0.76 respectively. The X-ray flux from OJ 287 is variable by a ratio of three from low to high state; PKS 0735+178 shows no indication of X-ray variability. The X-ray emission in OJ 287 is interpreted to be due to the synchrotron process from a volume common with either a beamed radio component or a stationary optical component. In PKS 0735+178, where the X-ray emission is most likely due to the Compton process operating in one of the VLBI radio components. The synchrotron self-Compton process with modest kinematic Doppler factors predicts the measured X-ray flux from PKS 0735+178 and lower than the measured flux in OJ 287.

37 CFR 2.155 - Notice of publication.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 37 Patents, Trademarks, and Copyrights 1 2011-07-01 2011-07-01 false Notice of publication. 2.155... COMMERCE RULES OF PRACTICE IN TRADEMARK CASES Publication of Marks Registered Under 1905 Act § 2.155 Notice of publication. The Office will send the registrant a notice of publication of the mark and of the...

37 CFR 2.155 - Notice of publication.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 37 Patents, Trademarks, and Copyrights 1 2013-07-01 2013-07-01 false Notice of publication. 2.155... COMMERCE RULES OF PRACTICE IN TRADEMARK CASES Publication of Marks Registered Under 1905 Act § 2.155 Notice of publication. The Office will send the registrant a notice of publication of the mark and of the...

Fermi LAT detection of a GeV flare from the BL Lac object PKS 2233-148

NASA Astrophysics Data System (ADS)

Ciprini, Stefano

2012-06-01

The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed gamma-ray flaring activity from a source positionally consistent with the BL Lac object PKS 2233-148 (also known as 2FGL J2236.5-1431, Nolan et al. 2012, ApJS, 199, 31, and OY -156) placed at R.A.: 339.1420296 deg, Dec.: -14.5561633 (J2000, Petrov et al. 2008, AJ, 136, 580). No redshift for the source has been measured up to now, demonstrating the BL Lac object character type of this source.

GLAST answers about high-energy peaked BL Lacs: double-humped {gamma}-ray peak and extreme accelerators?

DOE Office of Scientific and Technical Information (OSTI.GOV)

Costamante, L.; Aharonian, F.; Khangulyan, D.

2007-07-12

An often overlooked fact is that the MeV-GeV emission from High-energy peaked BL Lacs (HBL) is basically unknown: there are only 3 objects of this type among all EGRET identified blazars with measured spectra. GLAST will be able to measure the spectrum for many of them, in particular TeV-blazars, and surprises are expected. GLAST will tell if the {gamma}-ray peak in some HBL is actually a ''double peak'', as suggested by the comparison of EGRET and HESS data in PKS 2155-304, We also remind and argue that a new class of BL Lacs could exist, where particles are shock-accelerated nearmore » the maximum possible rate, characterized by the synchrotron emission peaking in the GLAST band (100 MeV - few GeV). Such objects could easily have escaped detection or identification so far, and could now be unveiled by GLAST.« less

Observations and analysis activities of the International Ultraviolet Explorer satellite telescope

NASA Technical Reports Server (NTRS)

Shull, J. Michael

1996-01-01

The funds from this grant were used to support observations and analysis with the International Ultraviolet Explorer (IUE) satellite telescope. The main area of scientific research concerned the variability analyses of ultraviolet spectra of Active Galactic Nuclei, primarily quasars, Seyfert galaxies, and BL Lacertae objects. The Colorado group included, at various times, the P.I. (J.M. Shull), Research Associate Dr. Rick Edelson, and graduate students Jon Saken, Elise Sachs, and Steve Penton. A portion of the work was also performed by CU undergraduate student Cheong-ming Fu. A major product of the effort was a database of all IUE spectra of active galactic nuclei. This database is being analyzed to obtain spectral indices, line fluxes, and continuum fluxes for over 500 AGN. As a by-product of this project, we implemented a new, improved technique of spectral extraction of IUE spectra, which has been used in several AGN-WATCH campaigns (on the Seyfert galaxy NGC 4151 and on the BL Lac object PKS 2155-304).

X-Ray Intraday Variability of Five TeV Blazars with NuSTAR

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pandey, Ashwani; Gupta, Alok C.; Wiita, Paul J., E-mail: ashwanitapan@gmail.com, E-mail: acgupta30@gmail.com, E-mail: wiitap@tcnj.edu

We have examined 40 Nuclear Spectroscopic Telescope Array ( NuSTAR ) light curves (LCs) of five TeV emitting high synchrotron peaked blazars: 1ES 0229+200, Mrk 421, Mrk 501, 1ES 1959+650, and PKS 2155−304. Four of the blazars showed intraday variability in the NuSTAR energy range of 3–79 keV. Using an autocorrelation function analysis we searched for intraday variability timescales in these LCs and found indications of several between 2.5 and 32.8 ks in eight LCs of Mrk 421, a timescale around 8.0 ks for one LC of Mrk 501, and timescales of 29.6 and 57.4 ks in two LCs ofmore » PKS 2155-304. The other two blazars’ LCs do not show any evidence for intraday variability timescales shorter than the lengths of those observations; however, the data were both sparser and noisier for them. We found positive correlations with zero lag between soft (3–10 keV) and hard (10–79 keV) bands for most of the LCs, indicating that their emissions originate from the same electron population. We examined spectral variability using a hardness ratio analysis and noticed a general “harder-when-brighter” behavior. The 22 LCs of Mrk 421 observed between 2012 July and 2013 April show that this source was in a quiescent state for an extended period of time and then underwent an unprecedented double-peaked outburst while monitored on a daily basis during 2013 April 10–16. We briefly discuss models capable of explaining these blazar emissions.« less

Near-infrared and gamma-ray monitoring of TANAMI gamma-ray bright sources

DOE PAGES

Nesci, R.; Tosti, G.; Pursimo, T.; ...

2013-06-18

Context. We present that spectral energy distribution and its variability are basic tools for understanding the physical processes operating in active galactic nuclei (AGN). Aims. In this paper we report the results of a one-year near-infrared (NIR) and optical monitoring of a sample of 22 AGN known to be gamma-ray emitters, aimed at discovering correlations between optical and gamma-ray emission. Methods. We observed our objects with the Rapid Eye Mount (REM) telescope in J,H,K, and R bands nearly twice every month during their visibility window and derived light curves and spectral indexes. We also analyzed the gamma-ray data from themore » Fermi gamma-ray Space Telescope, making weekly averages. Results. Six sources were never detected during our monitoring, proving to be fainter than their historical Two micron all sky survey (2MASS) level. All of the sixteen detected sources showed marked flux density variability, while the spectral indexes remained unchanged within our sensitivity limits. Steeper sources showed, on average, a larger variability. From the NIR light curves we also computed a variability speed index for each detected source. Only one source (PKS 0208-512) underwent an NIR flare during our monitoring. Half of the sources showed a regular flux density trend on a one-year time scale, but do not show any other peculiar characteristic. The broadband spectral index α ro appears to be a good proxy of the NIR spectral index only for BL Lac objects. No clear correlation between NIR and gamma-ray data is evident in our data, save for PKS 0537-441, PKS 0521-360, PKS 2155-304, and PKS 1424-418. In conclusion, the gamma-ray/NIR flux ratio showed a large spread, QSO being generally gamma-louder than BL Lac, with a marked correlation with the estimated peak frequency (ν peak) of the synchrotron emission.« less

8 CFR 215.5 - Hearing procedure before special inquiry officer.

Code of Federal Regulations, 2010 CFR

2010-01-01

... officer. 215.5 Section 215.5 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION... opportunity reserved to the alien to testify thereafter in his own behalf, if he so chooses. (4) The special... may request and, in the discretion of the special inquiry officer, be given an opportunity to...

Fermi LAT detection of a GeV flare from the high redshift BL Lac object PKS 2131-021

NASA Astrophysics Data System (ADS)

Ciprini, Stefano

2012-08-01

The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed gamma-ray flaring activity from a source positionally consistent with the BL Lac object PKS 2131-021 (also known as 2FGL J2133.8-0154, Nolan et al. 2012, ApJS, 199, 31, and 4C -02.81) placed at radio coordinates R.A.: 323.5429567 deg, Dec.: -1.8881217 deg (J2000, Johnston et al. 1995, AJ, 110, 880).

PKS 0537-441 - A gravitationally lensed blazar?

NASA Astrophysics Data System (ADS)

Stickel, M.; Fried, J. W.; Kuehr, H.

1988-11-01

Deep direct optical imaging data and spectroscopic observations of the southern blazar PKS 0537-441 (z = 0.894) and a neighboring galaxy are reported. The blazar has an extended, spatially resolved appearance. Image decomposition reveals a foreground disk galaxy seen nearly face-on which lies along the line of sight to the blazar. This foreground galaxy is mainly responsible for the extended image of PKS 0537-441, and its morphology is similar to that of a neighboring disk galaxy 11 arcsec to the east and slightly south of the blazar with a redshift of z = 0.186. Both objects presumably form a close pair at the same redshift. It is argued that the observed properties of the blazar are influenced by gravitational lensing in the foreground galaxy.

Strong intraday variability in the southern blazar PKS 0537-441 at 1.42 GHz

NASA Astrophysics Data System (ADS)

Romero, G. E.; Combi, J. A.; Colomb, F. R.

1994-08-01

Results of intraday variability observations with a sampling of ~20 minutes of the southern blazars PKS 0521-365 and PKS 0537-441 at 1.42 GHz are presented. PKS 0521-365 did not display flux density variability whilst PKS 0537-441 showed strong fluctuations with a major outburst towards J.D. 2449011 caracterized by a fluctuation index of ~15%, variability amplitudes of ~45% and time scales of ~10^4^s. After a discussion of possible scenarios for such kind of variability, this extremely violent behaviour is interpreted in terms of strong scattering by compact ionized structures in the interstellar medium. The physical properties of the refractors are estimated from the observed light curves, and a brief discussion about the possible origin of these objects is presented.

The HI Environment of Nearby Lyman-alpha Absorbers

NASA Technical Reports Server (NTRS)

VanGorkom, J. H.; Carilli, C. L.; Stocke, John T.; Perlman, Eric S.; Shull, J. Michael

1996-01-01

We present the results of a VLA and WSRT search for H I emission from the vicinity of seven nearby clouds, which were observed in Ly-alpha absorption with HST toward Mrk 335, Mrk 501, and PKS 2155-304. Around the absorbers, we searched a volume of 4O' x 40' x 1000 km/s; for one of the absorbers we probed a velocity range of only 600 km/s. The H I mass sensitivity (5 sigma) very close to the lines of sight varies from 5 x 10(exp 6) solar mass at best to 5 x 10(exp 8) solar mass at worst. We detected H I emission in the vicinity of four out of seven absorbers. The closest galaxy we find to the absorbers is a small dwarf galaxy at a projected distance of 68 h(exp -1) kpc from the sight line toward Mrk 335. This optically uncataloged galaxy has the same velocity (V = 1970 km/s) as one of the absorbers, is fainter than the SMC, and has an H I mass of only 4 x 10(exp 7) solar mass. We found a somewhat more luminous galaxy at exactly the velocity (V = 5100 km/s) of one of the absorbers toward PKS 2155-304 at a projected distance of 230 h(exp -1) kpc from the sight line. Two other, stronger absorbers toward PKS 2155-304 at V approx. 17,000 km/s appear to be associated with a loose group of three bright spiral galaxies, at projected distances of 300 to 600 h(exp -1) kpc. These results support the conclusions emerging from optical searches that most nearby Ly-alpha forest clouds trace the large-scale structures outlined by the optically luminous galaxies, although this is still based on small-number statistics. We do not find any evidence from the H I distribution or kinematics that there is a physical association between an absorber and its closest galaxy. While the absorbing clouds are at the systemic velocity of the galaxies, the H I extent of the galaxies is fairly typical, and at least an order of magnitude smaller than the projected distance to the sight line at which the absorbers are seen. On the other hand, we also do not find evidence against such a connection. In

The X-ray spectra of the BL Lacertae objects PKS 0548 - 322 and 3C 66A

NASA Technical Reports Server (NTRS)

Maccacaro, T.; Maccagni, D.; Tarenghi, M.

1983-01-01

Einstein Observatory simultaneous imaging proportional counter and monitor proportional counter data are combined in order to derive the energy spectra of the BL Lac objects PKS 0548-322 and 3C 66A between 0.2 and 10 keV. While the latter is found to be variable in both intensity and spectral shape, the former, although constant in the present data, is found to have experienced a spectrum variation in view of results from other experiments. Attention is given to the implications of flux and spectral variability in BL Lac objects for models of X-ray emission mechanisms. It is suggested that the wide spread of the spectral index distribution is due to the detection of the highly variable synchrotron-produced X-rays that are generally undetected in QSOs.

Host galaxy and environment of the BL Lacertae object PKS 0548-322: Observations with subarcsecond resolution

NASA Technical Reports Server (NTRS)

Falomo, Renato; Pesce, Joseph E.; Treves, Aldo

1995-01-01

We report on direct, subarcsecond resolution imaging of the nebulosity and spectroscopy of galaxies in the field of the BL Lacertae object PKS 0548-322. Surface photometry of the nebulosity is used to derive the properties of the host galaxy (M(sub V) = -23.4), which exhibits signs of interaction with a close companion galaxy at approximately 25 kpc. The radial brightness profile of the nebulosity is well fitted by the contribution of a bulge (r(exp 1/4)) plus a point source and a small internal disk. An analysis of the galaxies in the field shows that the source is located in a rich cluster of galaxies. Spectra of five galaxies in the field indicate that they are at the same redshift as the BL Lac object, thus supporting the imaging result of a surrounding cluster associated with the BL Lac. This cluster is most likely Abell S0549.

49 CFR 215.5 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-10-01

... TRANSPORTATION RAILROAD FREIGHT CAR SAFETY STANDARDS General § 215.5 Definitions. As used in this part: (a) Break... significantly diminish the strength of the member are not considered to be “cracked”; (c) Railroad freight car means a car designed to carry freight, or railroad personnel, by rail and includes a: (1) Box car; (2...

49 CFR 215.5 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-10-01

... TRANSPORTATION RAILROAD FREIGHT CAR SAFETY STANDARDS General § 215.5 Definitions. As used in this part: (a) Break... significantly diminish the strength of the member are not considered to be “cracked”; (c) Railroad freight car means a car designed to carry freight, or railroad personnel, by rail and includes a: (1) Box car; (2...

49 CFR 215.5 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... TRANSPORTATION RAILROAD FREIGHT CAR SAFETY STANDARDS General § 215.5 Definitions. As used in this part: (a) Break... significantly diminish the strength of the member are not considered to be “cracked”; (c) Railroad freight car means a car designed to carry freight, or railroad personnel, by rail and includes a: (1) Box car; (2...

49 CFR 215.5 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-10-01

... TRANSPORTATION RAILROAD FREIGHT CAR SAFETY STANDARDS General § 215.5 Definitions. As used in this part: (a) Break... significantly diminish the strength of the member are not considered to be “cracked”; (c) Railroad freight car means a car designed to carry freight, or railroad personnel, by rail and includes a: (1) Box car; (2...

47 CFR 27.1102 - Designated Entities in the 1710-1755 MHz and 2110-2155 MHz bands.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 2110-2155 MHz bands. 27.1102 Section 27.1102 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES 1710-1755 MHz, 2110-2155... the 1710-1755 MHz and 2110-2155 MHz bands. (a) Eligibility for small business provisions. (1) A small...

Multifrequency observations of the BL Lacertae object PKS 0537 - 441

NASA Technical Reports Server (NTRS)

Maraschi, L.; Treves, A.; Schwartz, D. A.; Tanzi, E. G.

1985-01-01

PKS 0537 - 441 was repeatedly observed in the UV band with the International Ultraviolet Explorer and in the X-ray with the Einstein Observatory. On September 27, 1980, simultaneous observations in the two bands were obtained. Near-infrared photometry preceding and following the simultaneous observations by about one month is available from the literature, as is radio monitoring at 408 and 5000 MHz. Comparison of the observed X-ray flux with that predicted by the standard synchrotron self-Compton formalism, with a source dimension deduced from radio variability at 5 GHz, indicates that this component of the radio emission must be moving at relativistic speed with an effective projected Doppler beaming factor of about 10.

Extended X-ray emission in PKS 1718-649

NASA Astrophysics Data System (ADS)

Beuchert, T.; Rodríguez-Ardila, A.; Moss, V. A.; Schulz, R.; Kadler, M.; Wilms, J.; Angioni, R.; Callingham, J. R.; Gräfe, C.; Krauß, F.; Kreikenbohm, A.; Langejahn, M.; Leiter, K.; Maccagni, F. M.; Müller, C.; Ojha, R.; Ros, E.; Tingay, S. J.

2018-04-01

PKS 1718-649 is one of the closest and most comprehensively studied candidates of a young active galactic nucleus (AGN) that is still embedded in its optical host galaxy. The compact radio structure, with a maximal extent of a few parsecs, makes it a member of the group of compact symmetric objects (CSO). Its environment imposes a turnover of the radio synchrotron spectrum towards lower frequencies, also classifying PKS 1718-649 as gigahertz-peaked radio spectrum (GPS) source. Its close proximity has allowed the first detection of extended X-ray emission in a GPS/CSO source with Chandra that is for the most part unrelated to nuclear feedback. However, not much is known about the nature of this emission. By co-adding all archival Chandra data and complementing these datasets with the large effective area of XMM-Newton, we are able to study the detailed physics of the environment of PKS 1718-649. Not only can we confirm that the bulk of the ≲kiloparsec-scale environment emits in the soft X-rays, but we also identify the emitting gas to form a hot, collisionally ionized medium. While the feedback of the central AGN still seems to be constrained to the inner few parsecs, we argue that supernovae are capable of producing the observed large-scale X-ray emission at a rate inferred from its estimated star formation rate.

Bacterial competition reveals differential regulation of the pks genes by Bacillus subtilis.

PubMed

Vargas-Bautista, Carol; Rahlwes, Kathryn; Straight, Paul

2014-02-01

Bacillus subtilis is adaptable to many environments in part due to its ability to produce a broad range of bioactive compounds. One such compound, bacillaene, is a linear polyketide/nonribosomal peptide. The pks genes encode the enzymatic megacomplex that synthesizes bacillaene. The majority of pks genes appear to be organized as a giant operon (>74 kb from pksC-pksR). In previous work (P. D. Straight, M. A. Fischbach, C. T. Walsh, D. Z. Rudner, and R. Kolter, Proc. Natl. Acad. Sci. U. S. A. 104:305-310, 2007, doi:10.1073/pnas.0609073103), a deletion of the pks operon in B. subtilis was found to induce prodiginine production by Streptomyces coelicolor. Here, colonies of wild-type B. subtilis formed a spreading population that induced prodiginine production from Streptomyces lividans, suggesting differential regulation of pks genes and, as a result, bacillaene. While the parent colony showed widespread induction of pks expression among cells in the population, we found the spreading cells uniformly and transiently repressed the expression of the pks genes. To identify regulators that control pks genes, we first determined the pattern of pks gene expression in liquid culture. We next identified mutations in regulatory genes that disrupted the wild-type pattern of pks gene expression. We found that expression of the pks genes requires the master regulator of development, Spo0A, through its repression of AbrB and the stationary-phase regulator, CodY. Deletions of degU, comA, and scoC had moderate effects, disrupting the timing and level of pks gene expression. The observed patterns of expression suggest that complex regulation of bacillaene and other antibiotics optimizes competitive fitness for B. subtilis.

40 CFR 799.2155 - Commercial hexane.

Code of Federal Regulations, 2013 CFR

2013-07-01

... least 40 liquid volume percent n-hexane (CAS No. 110-54-3) and at least 5 liquid volume percent... contains at least 40 liquid volume percent but no more than 55 liquid volume percent n-hexane and no less... 40 Protection of Environment 33 2013-07-01 2013-07-01 false Commercial hexane. 799.2155 Section...

40 CFR 799.2155 - Commercial hexane.

Code of Federal Regulations, 2014 CFR

2014-07-01

... least 40 liquid volume percent n-hexane (CAS No. 110-54-3) and at least 5 liquid volume percent... contains at least 40 liquid volume percent but no more than 55 liquid volume percent n-hexane and no less... 40 Protection of Environment 32 2014-07-01 2014-07-01 false Commercial hexane. 799.2155 Section...

Bacterial Competition Reveals Differential Regulation of the pks Genes by Bacillus subtilis

PubMed Central

Vargas-Bautista, Carol; Rahlwes, Kathryn

2014-01-01

Bacillus subtilis is adaptable to many environments in part due to its ability to produce a broad range of bioactive compounds. One such compound, bacillaene, is a linear polyketide/nonribosomal peptide. The pks genes encode the enzymatic megacomplex that synthesizes bacillaene. The majority of pks genes appear to be organized as a giant operon (>74 kb from pksC-pksR). In previous work (P. D. Straight, M. A. Fischbach, C. T. Walsh, D. Z. Rudner, and R. Kolter, Proc. Natl. Acad. Sci. U. S. A. 104:305–310, 2007, doi:10.1073/pnas.0609073103), a deletion of the pks operon in B. subtilis was found to induce prodiginine production by Streptomyces coelicolor. Here, colonies of wild-type B. subtilis formed a spreading population that induced prodiginine production from Streptomyces lividans, suggesting differential regulation of pks genes and, as a result, bacillaene. While the parent colony showed widespread induction of pks expression among cells in the population, we found the spreading cells uniformly and transiently repressed the expression of the pks genes. To identify regulators that control pks genes, we first determined the pattern of pks gene expression in liquid culture. We next identified mutations in regulatory genes that disrupted the wild-type pattern of pks gene expression. We found that expression of the pks genes requires the master regulator of development, Spo0A, through its repression of AbrB and the stationary-phase regulator, CodY. Deletions of degU, comA, and scoC had moderate effects, disrupting the timing and level of pks gene expression. The observed patterns of expression suggest that complex regulation of bacillaene and other antibiotics optimizes competitive fitness for B. subtilis. PMID:24187085

40 CFR 62.2155 - Identification of plan-negative declaration.

Code of Federal Regulations, 2010 CFR

2010-07-01

... District of Columbia Emissions from Existing Commercial/industrial Solid Waste Incineration Units § 62.2155... commercial/industrial solid waste incineration units within the District of Columbia that are subject to 40...

40 CFR 62.2155 - Identification of plan-negative declaration.

Code of Federal Regulations, 2011 CFR

2011-07-01

... District of Columbia Emissions from Existing Commercial/industrial Solid Waste Incineration Units § 62.2155... commercial/industrial solid waste incineration units within the District of Columbia that are subject to 40...

Eukaryotic Protein Kinases (ePKs) of the Helminth Parasite Schistosoma mansoni

PubMed Central

2011-01-01

Background Schistosomiasis remains an important parasitic disease and a major economic problem in many countries. The Schistosoma mansoni genome and predicted proteome sequences were recently published providing the opportunity to identify new drug candidates. Eukaryotic protein kinases (ePKs) play a central role in mediating signal transduction through complex networks and are considered druggable targets from the medical and chemical viewpoints. Our work aimed at analyzing the S. mansoni predicted proteome in order to identify and classify all ePKs of this parasite through combined computational approaches. Functional annotation was performed mainly to yield insights into the parasite signaling processes relevant to its complex lifestyle and to select some ePKs as potential drug targets. Results We have identified 252 ePKs, which corresponds to 1.9% of the S. mansoni predicted proteome, through sequence similarity searches using HMMs (Hidden Markov Models). Amino acid sequences corresponding to the conserved catalytic domain of ePKs were aligned by MAFFT and further used in distance-based phylogenetic analysis as implemented in PHYLIP. Our analysis also included the ePK homologs from six other eukaryotes. The results show that S. mansoni has proteins in all ePK groups. Most of them are clearly clustered with known ePKs in other eukaryotes according to the phylogenetic analysis. None of the ePKs are exclusively found in S. mansoni or belong to an expanded family in this parasite. Only 16 S. mansoni ePKs were experimentally studied, 12 proteins are predicted to be catalytically inactive and approximately 2% of the parasite ePKs remain unclassified. Some proteins were mentioned as good target for drug development since they have a predicted essential function for the parasite. Conclusions Our approach has improved the functional annotation of 40% of S. mansoni ePKs through combined similarity and phylogenetic-based approaches. As we continue this work, we will

The Varied Variability of PKS 0736+017

NASA Astrophysics Data System (ADS)

Clements, S. D.; Cubides, L. A.; Greiwe, C. L.; Habermas, K. S.; Jenks, A. K.; Long, A. M.; Patel, J. A.; Torres, Y. V.

2003-05-01

The flat spectrum radio quasar PKS 0736+017 has been an exciting observing target, exhibiting diverse optical variability behaviors and even sharing its field one evening with a minor planet. The behavior of PKS 0736+017 has included persistently faint and quiescent periods, episodes of quasi-periodic microvariability, dramatic flaring events, and periods of unusual oscillations. These assorted behaviors are examined, with particular emphasis on the quasi-periodic variations and unusual oscillations that accompanied a dramatic flare.

PKS1 plays a role in red-light-based positive phototropism in roots.

PubMed

Molas, Maria Lia; Kiss, John Z

2008-06-01

Aerial parts of plants curve towards the light (i.e. positive phototropism), and roots typically grow away from the light (i.e. negative phototropism). In addition, Arabidopsis roots exhibit positive phototropism relative to red light (RL), and this response is mediated by phytochromes A and B (phyA and phyB). Upon light stimulation, phyA and phyB interact with the phytochrome kinase substrate (PKS1) in the cytoplasm. In this study, we investigated the role of PKS1, along with phyA and phyB, in the positive phototropic responses to RL in roots. Using a high-resolution feedback system, we studied the phenotypic responses of roots of phyA, phyB, pks1, phyA pks1 and phyB pks1 null mutants as well as the PKS1-overexpressing line in response to RL. PKS1 emerged as an intermediary in the signalling pathways and appears to promote a negative curvature to RL in roots. In addition, phyA and phyB were both essential for a positive response to RL and act in a complementary fashion. However, either photoreceptor acting without the other results in negative curvature in response to red illumination so that the mode of action differs depending on whether phyA and phyB act independently or together. Our results suggest that PKS1 is part of a signalling pathway independent of phyA and phyB and that PKS1 modulates RL-based root phototropism.

Emitting electron spectra and acceleration processes in the jet of PKS 0447-439

NASA Astrophysics Data System (ADS)

Zhou, Yao; Yan, Dahai; Dai, Benzhong; Zhang, Li

2014-02-01

We investigate the electron energy distributions (EEDs) and the corresponding acceleration processes in the jet of PKS 0447-439, and estimate its redshift through modeling its observed spectral energy distribution (SED) in the frame of a one-zone synchrotron-self Compton (SSC) model. Three EEDs formed in different acceleration scenarios are assumed: the power-law with exponential cut-off (PLC) EED (shock-acceleration scenario or the case of the EED approaching equilibrium in the stochastic-acceleration scenario), the log-parabolic (LP) EED (stochastic-acceleration scenario and the acceleration dominating), and the broken power-law (BPL) EED (no acceleration scenario). The corresponding fluxes of both synchrotron and SSC are then calculated. The model is applied to PKS 0447-439, and modeled SEDs are compared to the observed SED of this object by using the Markov Chain Monte Carlo method. The results show that the PLC model fails to fit the observed SED well, while the LP and BPL models give comparably good fits for the observed SED. The results indicate that it is possible that a stochastic acceleration process acts in the emitting region of PKS 0447-439 and the EED is far from equilibrium (acceleration dominating) or no acceleration process works (in the emitting region). The redshift of PKS 0447-439 is also estimated in our fitting: z = 0.16 ± 0.05 for the LP case and z = 0.17 ± 0.04 for BPL case.

Bioinformatic perspectives on NRPS/PKS megasynthases: advances and challenges.

PubMed

Jenke-Kodama, Holger; Dittmann, Elke

2009-07-01

The increased understanding of both fundamental principles and mechanistic variations of NRPS/PKS megasynthases along with the unprecedented availability of microbial sequences has inspired a number of in silico studies of both enzyme families. The insights that can be extracted from these analyses go far beyond a rough classification of data and have turned bioinformatics into a frontier field of natural products research. As databases are flooded with NRPS/PKS gene sequence of microbial genomes and metagenomes, increasingly reliable structural prediction methods can help to uncover hidden treasures. Already, phylogenetic analyses have revealed that NRPS/PKS pathways should not simply be regarded as enzyme complexes, specifically evolved to product a selected natural product. Rather, they represent a collection of genetic opinions, allowing biosynthetic pathways to be shuffled in a process of perpetual chemical innovations and pathways diversification in nature can give impulses for specificities, protein interactions and genetic engineering of libraries of novel peptides and polyketides. The successful translation of the knowledge obtained from bioinformatic dissection of NRPS/PKS megasynthases into new techniques for drug discovery and design remain challenges for the future.

7 CFR 215.5 - Method of payment to States.

Code of Federal Regulations, 2012 CFR

2012-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL MILK PROGRAM FOR CHILDREN § 215.5 Method of payment to States. (a... Authorities and child-care institutions through presentation by designated State officials of a Payment...

7 CFR 215.5 - Method of payment to States.

Code of Federal Regulations, 2011 CFR

2011-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL MILK PROGRAM FOR CHILDREN § 215.5 Method of payment to States. (a... Authorities and child-care institutions through presentation by designated State officials of a Payment...

7 CFR 215.5 - Method of payment to States.

Code of Federal Regulations, 2013 CFR

2013-01-01

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7 CFR 215.5 - Method of payment to States.

Code of Federal Regulations, 2014 CFR

2014-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL MILK PROGRAM FOR CHILDREN § 215.5 Method of payment to States. (a... Authorities and child-care institutions through presentation by designated State officials of a Payment...

7 CFR 215.5 - Method of payment to States.

Code of Federal Regulations, 2010 CFR

2010-01-01

... AGRICULTURE CHILD NUTRITION PROGRAMS SPECIAL MILK PROGRAM FOR CHILDREN § 215.5 Method of payment to States. (a... Authorities and child-care institutions through presentation by designated State officials of a Payment... delay for the purpose for which drawn. Notwithstanding the foregoing provisions, if funds are made...

Comparative genomic analysis of the PKS genes in five species and expression analysis in upland cotton

PubMed Central

Cheng, Xi; Wang, Yanan; Abdullah, Muhammad; Li, Manli; Li, Dahui; Gao, Junshan

2017-01-01

Plant type III polyketide synthase (PKS) can catalyse the formation of a series of secondary metabolites with different structures and different biological functions; the enzyme plays an important role in plant growth, development and resistance to stress. At present, the PKS gene has been identified and studied in a variety of plants. Here, we identified 11 PKS genes from upland cotton (Gossypium hirsutum) and compared them with 41 PKS genes in Populus tremula, Vitis vinifera, Malus domestica and Arabidopsis thaliana. According to the phylogenetic tree, a total of 52 PKS genes can be divided into four subfamilies (I–IV). The analysis of gene structures and conserved motifs revealed that most of the PKS genes were composed of two exons and one intron and there are two characteristic conserved domains (Chal_sti_synt_N and Chal_sti_synt_C) of the PKS gene family. In our study of the five species, gene duplication was found in addition to Arabidopsis thaliana and we determined that purifying selection has been of great significance in maintaining the function of PKS gene family. From qRT-PCR analysis and a combination of the role of the accumulation of proanthocyanidins (PAs) in brown cotton fibers, we concluded that five PKS genes are candidate genes involved in brown cotton fiber pigment synthesis. These results are important for the further study of brown cotton PKS genes. It not only reveals the relationship between PKS gene family and pigment in brown cotton, but also creates conditions for improving the quality of brown cotton fiber. PMID:29104824

Fermi LAT detection of renewed and strong GeV gamma-ray flares from blazars PKS 0903-57 and PKS 0346-27

NASA Astrophysics Data System (ADS)

Ciprini, Stefano

2018-05-01

The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed high-level gamma-ray activity from sources positionally consistent with the active galaxy PKS 0903-57 (also known as MRC 0903-573 and 3FGL J0904.8-5734, Acero et al. 2015, ApJS, 218, 23) and with the flat spectrum radio quasar PKS 0346-27 (also known as OE -278, TXS 0346-279, MRC 0346-279 and 3FGL J0348.6-2748).

Biosynthesis of the mycotoxin tenuazonic acid by a fungal NRPS–PKS hybrid enzyme

PubMed Central

Yun, Choong-Soo; Motoyama, Takayuki; Osada, Hiroyuki

2015-01-01

Tenuazonic acid (TeA) is a well-known mycotoxin produced by various plant pathogenic fungi. However, its biosynthetic gene has been unknown to date. Here we identify the TeA biosynthetic gene from Magnaporthe oryzae by finding two TeA-inducing conditions of a low-producing strain. We demonstrate that TeA is synthesized from isoleucine and acetoacetyl-coenzyme A by TeA synthetase 1 (TAS1). TAS1 is a unique non-ribosomal peptide synthetase and polyketide synthase (NRPS–PKS) hybrid enzyme that begins with an NRPS module. In contrast to other NRPS/PKS hybrid enzymes, the PKS portion of TAS1 has only a ketosynthase (KS) domain and this domain is indispensable for TAS1 activity. Phylogenetic analysis classifies this KS domain as an independent clade close to type I PKS KS domain. We demonstrate that the TAS1 KS domain conducts the final cyclization step for TeA release. These results indicate that TAS1 is a unique type of NRPS–PKS hybrid enzyme. PMID:26503170

K2-155: A Bright Metal-poor M Dwarf with Three Transiting Super-Earths

NASA Astrophysics Data System (ADS)

Hirano, Teruyuki; Dai, Fei; Livingston, John H.; Fujii, Yuka; Cochran, William D.; Endl, Michael; Gandolfi, Davide; Redfield, Seth; Winn, Joshua N.; Guenther, Eike W.; Prieto-Arranz, Jorge; Albrecht, Simon; Barragan, Oscar; Cabrera, Juan; Cauley, P. Wilson; Csizmadia, Szilard; Deeg, Hans; Eigmüller, Philipp; Erikson, Anders; Fridlund, Malcolm; Fukui, Akihiko; Grziwa, Sascha; Hatzes, Artie P.; Korth, Judith; Narita, Norio; Nespral, David; Niraula, Prajwal; Nowak, Grzegorz; Pätzold, Martin; Palle, Enric; Persson, Carina M.; Rauer, Heike; Ribas, Ignasi; Smith, Alexis M. S.; Van Eylen, Vincent

2018-03-01

We report on the discovery of three transiting super-Earths around K2-155 (EPIC 210897587), a relatively bright early M dwarf (V = 12.81 mag) observed during Campaign 13 of the NASA K2 mission. To characterize the system and validate the planet candidates, we conducted speckle imaging and high-dispersion optical spectroscopy, including radial velocity measurements. Based on the K2 light curve and the spectroscopic characterization of the host star, the planet sizes and orbital periods are {1.55}-0.17+0.20 {R}\\oplus and 6.34365 ± 0.00028 days for the inner planet; {1.95}-0.22+0.27 {R}\\oplus and 13.85402 ± 0.00088 days for the middle planet; and {1.64}-0.17+0.18 {R}\\oplus and 40.6835 ± 0.0031 days for the outer planet. The outer planet (K2-155d) is near the habitable zone, with an insolation 1.67 ± 0.38 times that of the Earth. The planet’s radius falls within the range between that of smaller rocky planets and larger gas-rich planets. To assess the habitability of this planet, we present a series of three-dimensional global climate simulations, assuming that K2-155d is tidally locked and has an Earth-like composition and atmosphere. We find that the planet can maintain a moderate surface temperature if the insolation proves to be smaller than ∼1.5 times that of the Earth. Doppler mass measurements, transit spectroscopy, and other follow-up observations should be rewarding, as K2-155 is one of the optically brightest M dwarfs known to harbor transiting planets.

The Polyketide Synthase Gene pks4 of Trichoderma reesei Provides Pigmentation and Stress Resistance

PubMed Central

Atanasova, Lea; Knox, Benjamin P.; Kubicek, Christian P.; Baker, Scott E.

2013-01-01

Species of the fungal genus Trichoderma (Hypocreales, Ascomycota) are well-known for their production of various secondary metabolites. Nonribosomal peptides and polyketides represent a major portion of these products. In a recent phylogenomic investigation of Trichoderma polyketide synthase (PKS)-encoding genes, the pks4 from T. reesei was shown to be an orthologue of pigment-forming PKSs involved in synthesis of aurofusarin and bikaverin in Fusarium spp. In this study, we show that deletion of this gene in T. reesei results in loss of green conidial pigmentation and in pigmentation alteration of teleomorph structures. It also has an impact on conidial cell wall stability and the antagonistic abilities of T. reesei against other fungi, including formation of inhibitory metabolites. In addition, deletion of pks4 significantly influences the expression of other PKS-encoding genes of T. reesei. To our knowledge, this is the first indication that a low-molecular-weight pigment-forming PKS is involved in defense, mechanical stability, and stress resistance in fungi. PMID:24036343

RXTE, VLBA, Optical, and Radio Monitoring of the Quasars 3C 279, PKS 1510--089, and 3C 273

NASA Technical Reports Server (NTRS)

Marscher, A. P.; Jorstad, S. G.; Aller, M. F.; McHardy, I. M.; Balonek, T. J.

2001-01-01

We are continuing our combined RXTE X-ray, VLBA imaging (at 43 GHz), optical (several observatories), and radio (University of Michigan Radio Astronomy Observatory) monitoring of the quasars 3C 279 and PKS 1510-089, and have started similar monitoring of 3C 273. X-ray flares in 3C 279 and PKS 1510-089 are associated with ejections of superluminal components. In addition, there is a close connection between the optical and X-ray variability of 3C 279. There is a strong correlation between the 14.5 GHz and X-ray variability of PKS 1510-089 in 1997 and 1998 (with the radio leading the X-ray) that becomes weaker in subsequent years. X-ray fluctuations occur on a variety of timescales in 3C 273, with a major prolonged outburst in mid-2001. The lead author will discuss the correlations in terms of inverse Compton models for the X-ray emission coupled with synchrotron models for the lower-frequency radiation. Synchrotron self-Compton models can explain the "reverse" time lag in PKS 1510-089 is well as the variable correlation between the X-ray variations and those at lower frequencies in this object and in 3C 279.

Increased Gamma-ray Activity from the FSRQ PKS 1424-41

NASA Astrophysics Data System (ADS)

Ojha, Roopesh; Dutka, Michael

2012-10-01

The Large Area Telescope (LAT) on the Fermi Gamma-ray Space Telescope has observed increased gamma-ray emission from a source positionally coincident with the flat spectrum radio quasar PKS 1424-41 (1424-418; 2FGL J1428.0-4206, Nolan et al. 2012, ApJS, 199, 31). PKS 1424-41 has the coordinates RA=14h27m56.3s, DEC= -42d06'19.4", J2000, (Johnston et al. 1995, AJ, 110, 880).

Convergence of isoprene and polyketide biosynthetic machinery: isoprenyl-S-carrier proteins in the pksX pathway of Bacillus subtilis.

PubMed

Calderone, Christopher T; Kowtoniuk, Walter E; Kelleher, Neil L; Walsh, Christopher T; Dorrestein, Pieter C

2006-06-13

The pksX gene cluster from Bacillus subtilis is predicted to encode the biosynthesis of an as yet uncharacterized hybrid nonribosomal peptide/polyketide secondary metabolite. We used a combination of biochemical and mass spectrometric techniques to assign functional roles to the proteins AcpK, PksC, PksL, PksF, PksG, PksH, and PksI, and we conclude that they act to incorporate an acetate-derived beta-methyl branch on an acetoacetyl-S-carrier protein and ultimately generate a Delta(2)-isoprenyl-S-carrier protein. This work highlights the power of mass spectrometry to elucidate the functions of orphan biosynthetic enzymes, and it details a mechanism by which single-carbon beta-branches can be inserted into polyketide-like structures. This pathway represents a noncanonical route to the construction of prenyl units and serves as a prototype for the intersection of isoprenoid and polyketide biosynthetic manifolds in other natural product biosynthetic pathways.

H.E.S.S. discovery of VHE γ-rays from the quasar PKS 1510-089

NASA Astrophysics Data System (ADS)

H.E.S.S. Collaboration; Abramowski, A.; Acero, F.; Aharonian, F.; Akhperjanian, A. G.; Anton, G.; Balenderan, S.; Balzer, A.; Barnacka, A.; Becherini, Y.; Becker Tjus, J.; Behera, B.; Bernlöhr, K.; Birsin, E.; Biteau, J.; Bochow, A.; Boisson, C.; Bolmont, J.; Bordas, P.; Brucker, J.; Brun, F.; Brun, P.; Bulik, T.; Carrigan, S.; Casanova, S.; Cerruti, M.; Chadwick, P. M.; Chaves, R. C. G.; Cheesebrough, A.; Colafrancesco, S.; Cologna, G.; Conrad, J.; Couturier, C.; Dalton, M.; Daniel, M. K.; Davids, I. D.; Degrange, B.; Deil, C.; deWilt, P.; Dickinson, H. J.; Djannati-Ataï, A.; Domainko, W.; O'C. Drury, L.; Dubus, G.; Dutson, K.; Dyks, J.; Dyrda, M.; Egberts, K.; Eger, P.; Espigat, P.; Fallon, L.; Farnier, C.; Fegan, S.; Feinstein, F.; Fernandes, M. V.; Fernandez, D.; Fiasson, A.; Fontaine, G.; Förster, A.; Füßling, M.; Gajdus, M.; Gallant, Y. A.; Garrigoux, T.; Gast, H.; Giebels, B.; Glicenstein, J. F.; Glück, B.; Göring, D.; Grondin, M.-H.; Grudzińska, M.; Häffner, S.; Hague, J. D.; Hahn, J.; Hampf, D.; Harris, J.; Hauser, M.; Heinz, S.; Heinzelmann, G.; Henri, G.; Hermann, G.; Hillert, A.; Hinton, J. A.; Hofmann, W.; Hofverberg, P.; Holler, M.; Horns, D.; Jacholkowska, A.; Jahn, C.; Jamrozy, M.; Jung, I.; Kastendieck, M. A.; Katarzyński, K.; Katz, U.; Kaufmann, S.; Khélifi, B.; Klepser, S.; Klochkov, D.; Kluźniak, W.; Kneiske, T.; Kolitzus, D.; Komin, Nu.; Kosack, K.; Kossakowski, R.; Krayzel, F.; Krüger, P. P.; Laffon, H.; Lamanna, G.; Lefaucheur, J.; Lemoine-Goumard, M.; Lenain, J.-P.; Lennarz, D.; Lohse, T.; Lopatin, A.; Lu, C.-C.; Marandon, V.; Marcowith, A.; Masbou, J.; Maurin, G.; Maxted, N.; Mayer, M.; McComb, T. J. L.; Medina, M. C.; Méhault, J.; Menzler, U.; Moderski, R.; Mohamed, M.; Moulin, E.; Naumann, C. L.; Naumann-Godo, M.; de Naurois, M.; Nedbal, D.; Nguyen, N.; Niemiec, J.; Nolan, S. J.; Ohm, S.; de Oña Wilhelmi, E.; Opitz, B.; Ostrowski, M.; Oya, I.; Panter, M.; Parsons, R. D.; Paz Arribas, M.; Pekeur, N. W.; Pelletier, G.; Perez, J.; Petrucci, P.-O.; Peyaud, B.; Pita, S.; Pühlhofer, G.; Punch, M.; Quirrenbach, A.; Raab, S.; Raue, M.; Reimer, A.; Reimer, O.; Renaud, M.; de los Reyes, R.; Rieger, F.; Ripken, J.; Rob, L.; Rosier-Lees, S.; Rowell, G.; Rudak, B.; Rulten, C. B.; Sahakian, V.; Sanchez, D. A.; Santangelo, A.; Schlickeiser, R.; Schulz, A.; Schwanke, U.; Schwarzburg, S.; Schwemmer, S.; Sheidaei, F.; Skilton, J. L.; Sol, H.; Spengler, G.; Stawarz, Ł.; Steenkamp, R.; Stegmann, C.; Stinzing, F.; Stycz, K.; Sushch, I.; Szostek, A.; Tavernet, J.-P.; Terrier, R.; Tluczykont, M.; Trichard, C.; Valerius, K.; van Eldik, C.; Vasileiadis, G.; Venter, C.; Viana, A.; Vincent, P.; Völk, H. J.; Volpe, F.; Vorobiov, S.; Vorster, M.; Wagner, S. J.; Ward, M.; White, R.; Wierzcholska, A.; Wouters, D.; Zacharias, M.; Zajczyk, A.; Zdziarski, A. A.; Zech, A.; Zechlin, H. S.

2013-06-01

The quasar PKS 1510-089 (z = 0.361) was observed with the H.E.S.S. array of imaging atmospheric Cherenkov telescopes during high states in the optical and GeV bands, to search for very high energy (VHE, defined as E ≥ 0.1 TeV) emission. VHE γ-rays were detected with a statistical significance of 9.2 standard deviations in 15.8 h of H.E.S.S. data taken during March and April 2009. A VHE integral flux of I(0.15 TeV < E < 1.0 TeV)= (1.0 ± 0.2stat ± 0.2sys) × 10-11 cm-2 s-1 is measured. The best-fit power law to the VHE data has a photon index of Γ = 5.4 ± 0.7stat ± 0.3sys. The GeV and optical light curves show pronounced variability during the period of H.E.S.S. observations. However, there is insufficient evidence to claim statistically significant variability in the VHE data. Because of its relatively high redshift, the VHE flux from PKS 1510-089 should suffer considerable attenuation in the intergalactic space due to the extragalactic background light (EBL). Hence, the measured γ-ray spectrum is used to derive upper limits on the opacity due to EBL, which are found to be comparable with the previously derived limits from relatively-nearby BL Lac objects. Unlike typical VHE-detected blazars where the broadband spectrum is dominated by nonthermal radiation at all wavelengths, the quasar PKS 1510-089 has a bright thermal component in the optical to UV frequency band. Among all VHE detected blazars, PKS 1510-089 has the most luminous broad line region. The detection of VHE emission from this quasar indicates a low level of γ - γ absorption on the internal optical to UV photon field.

An unusually strong Einstein ring in the radio source PKS1830 - 211

NASA Technical Reports Server (NTRS)

Jauncey, D. L.; Reynolds, J. E.; Tzioumis, A. K.; Murphy, D. W.; Preston, R. A.; Jones, D. L.; Meier, D. L.; Hoard, D. W.; Lobdell, E. T.; Skjerve, L.

1991-01-01

High-resolution radio images of PKS1830 - 211 are obtained to study the possibility that the double structure is a gravitationally lensed object. The VLBI observations, taken from interferometric radiotelescope networks, reveal an elliptical ring that connects two bright spots of similar composition. Because the lens and the lensed object are closely aligned, and because of the structure of the two spots, the source is concluded to be a radio Einstein ring. The source is found to be close to the galactic plane, and the lens and the lensed object are extragalactic. The source is also found to be unusually bright, suggesting that it is aligned with a bright background source or amplified by some mechanism related to a source that is not so bright.

X-Ray Absorption Toward the Einstein Ring Source PKS 1830-211

NASA Technical Reports Server (NTRS)

Mathur, Smita; Nair, Sunita

1997-01-01

PKS 1830-211 is an unusually radio-loud gravitationally lensed quasar. In the radio spectrum, the system appears as two compact, dominant features surrounded by relatively extended radio emission that forms an Einstein ring. As the line of sight to it passes close to our Galactic center, PKS 1830-211 has not been detected in wave bands other than the radio and X-ray so far. Here we present X-ray data of PKS 1830-211 observed with ROSAT Position Sensitive Proportional Counter. The X-ray spectrum shows that absorption in excess of the Galactic contribution is highly likely, which at the redshift of the lensing galaxy (z(sub t)=0.886) corresponds to N(sub H)=3.5((sup 0.6)(sub -0.5))x10(exp 22) atoms sq cm. The effective optical extinction is large, A(sub V)(observed) is greater than or approximately 5.8. When corrected for this additional extinction, the two-point optical to X-ray slope alpha(sub ox) of PKS 1830-211 lies just within the observed range of quasars. It is argued here that both compact images must be covered by the X-ray absorber(s) that we infer to be the lensing galaxy (galaxies). The dust-to-gas ratio along the line of sight within the lensing galaxy is likely to be somewhat larger than for our Galaxy.

Molecular epidemiology and phylogenetic distribution of the Escherichia coli pks genomic island.

PubMed

Johnson, James R; Johnston, Brian; Kuskowski, Michael A; Nougayrede, Jean-Philippe; Oswald, Eric

2008-12-01

Epidemiological and phylogenetic associations of the pks genomic island of extraintestinal pathogenic Escherichia coli (ExPEC), which encodes the genotoxin colibactin, are incompletely defined. clbB and clbN (as markers for the 5' and 3' regions of the pks island, respectively), clbA and clbQ (as supplemental pks island markers), and 12 other putative ExPEC virulence genes were newly sought by PCR among 131 published E. coli isolates from hospitalized veterans (62 blood isolates and 69 fecal isolates). Blood and fecal isolates and clbB-positive and -negative isolates were compared for 66 newly and previously assessed traits. Among the 14 newly sought traits, clbB and clbN (colibactin polyketide synthesis system), hra (heat-resistant agglutinin), and vat (vacuolating toxin) were significantly associated with bacteremia. clbB and clbN identified a subset within phylogenetic group B2 with extremely high virulence scores and a high proportion of blood isolates. However, by multivariable analysis, other traits were more predictive of blood source than clbB and clbN were; indeed, among the newly sought traits, only pic significantly predicted bacteremia (negative association). By correspondence analysis, clbB and clbN were closely associated with group B2 and multiple B2-associated traits; by principal coordinate analysis, clbB and clbN partitioned the data set better than did blood versus fecal source. Thus, the pks island was significantly associated with bacteremia, multiple ExPEC-associated virulence genes, and group B2, and within group B2, it identified an especially high-virulence subset. This extends previous work regarding the pks island and supports investigation of the colibactin system as a potential therapeutic target.

A model for the flux-r.m.s. correlation in blazar variability or the minijets-in-a-jet statistical model

NASA Astrophysics Data System (ADS)

Biteau, J.; Giebels, B.

2012-12-01

Very high energy gamma-ray variability of blazar emission remains of puzzling origin. Fast flux variations down to the minute time scale, as observed with H.E.S.S. during flares of the blazar PKS 2155-304, suggests that variability originates from the jet, where Doppler boosting can be invoked to relax causal constraints on the size of the emission region. The observation of log-normality in the flux distributions should rule out additive processes, such as those resulting from uncorrelated multiple-zone emission models, and favour an origin of the variability from multiplicative processes not unlike those observed in a broad class of accreting systems. We show, using a simple kinematic model, that Doppler boosting of randomly oriented emitting regions generates flux distributions following a Pareto law, that the linear flux-r.m.s. relation found for a single zone holds for a large number of emitting regions, and that the skewed distribution of the total flux is close to a log-normal, despite arising from an additive process.

Reduced phototropism in pks mutants may be due to altered auxin-regulated gene expression or reduced lateral auxin transport.

PubMed

Kami, Chitose; Allenbach, Laure; Zourelidou, Melina; Ljung, Karin; Schütz, Frédéric; Isono, Erika; Watahiki, Masaaki K; Yamamoto, Kotaro T; Schwechheimer, Claus; Fankhauser, Christian

2014-02-01

Phototropism allows plants to orient their photosynthetic organs towards the light. In Arabidopsis, phototropins 1 and 2 sense directional blue light such that phot1 triggers phototropism in response to low fluence rates, while both phot1 and phot2 mediate this response under higher light conditions. Phototropism results from asymmetric growth in the hypocotyl elongation zone that depends on an auxin gradient across the embryonic stem. How phototropin activation leads to this growth response is still poorly understood. Members of the phytochrome kinase substrate (PKS) family may act early in this pathway, because PKS1, PKS2 and PKS4 are needed for a normal phototropic response and they associate with phot1 in vivo. Here we show that PKS proteins are needed both for phot1- and phot2-mediated phototropism. The phototropic response is conditioned by the developmental asymmetry of dicotyledonous seedlings, such that there is a faster growth reorientation when cotyledons face away from the light compared with seedlings whose cotyledons face the light. The molecular basis for this developmental effect on phototropism is unknown; here we show that PKS proteins play a role at the interface between development and phototropism. Moreover, we present evidence for a role of PKS genes in hypocotyl gravi-reorientation that is independent of photoreceptors. pks mutants have normal levels of auxin and normal polar auxin transport, however they show altered expression patterns of auxin marker genes. This situation suggests that PKS proteins are involved in auxin signaling and/or lateral auxin redistribution. © 2013 The Authors The Plant Journal © 2013 John Wiley & Sons Ltd.

The polyketide synthase gene pks4 is essential for sexual development and regulates fruiting body morphology in Sordaria macrospora.

PubMed

Schindler, Daniel; Nowrousian, Minou

2014-07-01

Filamentous ascomycetes have long been known as producers of a variety of secondary metabolites, many of which have toxic effects on other organisms. However, the role of these metabolites in the biology of the fungi that produce them remains in most cases enigmatic. A major group of fungal secondary metabolites are polyketides. They are chemically diverse, but have in common that their chemical scaffolds are synthesized by polyketide synthases (PKSs). In a previous study, we analyzed development-dependent expression of pks genes in the filamentous ascomycete Sordaria macrospora. Here, we show that a deletion mutant of the pks4 gene is sterile, producing only protoperithecia but no mature perithecia, whereas overexpression of pks4 leads to enlarged, malformed fruiting bodies. Thus, correct expression levels of pks4 are essential for wild type-like perithecia formation. The predicted PKS4 protein has a domain structure that is similar to homologs in other fungi, but conserved residues of a methyl transferase domain present in other fungi are mutated in PKS4. Expression of several developmental genes is misregulated in the pks4 mutant. Surprisingly, the development-associated app gene is not downregulated in the mutant, in contrast to all other previously studied mutants with a block at the protoperithecial stage. Our data show that the polyketide synthase gene pks4 is essential for sexual development and plays a role in regulating fruiting body morphology. Copyright © 2014 Elsevier Inc. All rights reserved.

Polyketide synthases of Diaporthe helianthi and involvement of DhPKS1 in virulence on sunflower.

PubMed

Ruocco, Michelina; Baroncelli, Riccardo; Cacciola, Santa Olga; Pane, Catello; Monti, Maurilia Maria; Firrao, Giuseppe; Vergara, Mariarosaria; Magnano di San Lio, Gaetano; Vannacci, Giovanni; Scala, Felice

2018-01-06

The early phases of Diaporthe helianthi pathogenesis on sunflower are characterized by the production of phytotoxins that may play a role in host colonisation. In previous studies, phytotoxins of a polyketidic nature were isolated and purified from culture filtrates of virulent strains of D. helianthi isolated from sunflower. A highly aggressive isolate (7/96) from France contained a gene fragment of a putative nonaketide synthase (lovB) which was conserved in a virulent D. helianthi population. In order to investigate the role of polyketide synthases in D. helianthi 7/96, a draft genome of this isolate was examined. We were able to find and phylogenetically analyse 40 genes putatively coding for polyketide synthases (PKSs). Analysis of their domains revealed that most PKS genes of D. helianthi are reducing PKSs, whereas only eight lacked reducing domains. Most of the identified PKSs have orthologs shown to be virulence factors or genetic determinants for toxin production in other pathogenic fungi. One of the genes (DhPKS1) corresponded to the previously cloned D. helianthi lovB gene fragment and clustered with a nonribosomal peptide synthetase (NRPS) -PKS hybrid/lovastatin nonaketide like A. nidulans LovB. We used DhPKS1 as a case study and carried out its disruption through Agrobacterium-mediated transformation in the isolate 7/96. D. helianthi DhPKS1 deleted mutants were less virulent to sunflower compared to the wild type, indicating a role for this gene in the pathogenesis of the fungus. The PKS sequences analysed and reported here constitute a new genomic resource that will be useful for further research on the biology, ecology and evolution of D. helianthi and generally of fungal plant pathogens.

Fermi LAT detection of renewed GeV flaring activity from PKS 0426-380

NASA Astrophysics Data System (ADS)

Ciprini, Stefano

2012-12-01

The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed gamma-ray flaring activity from a source positionally consistent with the BL Lac object PKS 0426-380 (also known as 2FGL J0428.6-3756, Nolan et al. 2012, ApJS, 199, 31, and RX J0428.6-3756) with radio coordinates R.A.: 67.16843 deg, Dec: -37.93877 deg, J2000 (Johnston et al. 1995, AJ, 110, 880) and redshift z=1.111 (Heidt et al....

Interstellar Scattering and the Einstein Ring PKS 1830-211

NASA Technical Reports Server (NTRS)

Jones, D. L.; Preston, R. A.; Murphy, D. W.; Meier, D. L.; Jauncey, D. L.; Reynolds, J. E.; Tziomis, A. K.

1995-01-01

High frequency (22 GHz) data have been used two resolve two compact components of the strong gravitational lens PKS 1830-211. The two bright components are at opposite sides of a one arcsecond diameter Einstein ring.

Characterisation of pks15/1 in clinical isolates of Mycobacterium tuberculosis from Mexico

PubMed Central

Zenteno-Cuevas, Roberto; Silva-Hernández, Francisco X; Mendoza-Damián, Fabiola; Ramírez-Hernández, Maria Dolores; Vázquez-Medina, Karen; Widrobo-García, Lorena; Cuellar-Sanchez, Aremy; Muñíz-Salazar, Raquel; Enciso-Moreno, Leonor; Pérez-Navarro, Lucia Monserrat; Enciso-Moreno, José Antonio

2013-01-01

Tuberculosis (TB) is an infectocontagious respiratory disease caused by members of the Mycobacterium tuberculosis complex. A 7 base pair (bp) deletion in the locus polyketide synthase (pks)15/1 is described as polymorphic among members of the M. tuberculosis complex, enabling the identification of Euro-American, Indo-Oceanic and Asian lineages. The aim of this study was to characterise this locus in TB isolates from Mexico. One hundred twenty clinical isolates were recovered from the states of Veracruz and Estado de Mexico. We determined the nucleotide sequence of a ± 400 bp fragment of the locus pks15/1, while genotypic characterisation was performed by spoligotyping. One hundred and fifty isolates contained the 7 bp deletion, while five had the wild type locus. Lineages X (22%), LAM (18%) and T (17%) were the most frequent; only three (2%) of the isolates were identified as Beijing and two (1%) EAI-Manila. The wild type pks15/1 locus was observed in all Asian lineage isolates tested. Our results confirm the utility of locus pks15/1 as a molecular marker for identifying Asian lineages of the M. tuberculosis complex. This marker could be of great value in the epidemiological surveillance of TB, especially in countries like Mexico, where the prevalence of such lineages is unknown. PMID:24037193

PKS 2123-463: A Confirmed Gamma-ray Blazar at High Redshift

NASA Technical Reports Server (NTRS)

DAmmando, F.; Rau, A.; Schady, P.; Finke, J.; Orienti, M.; Greiner, J.; Kann, D. A.; Ojha, R.; Foley, A. R.; Stevens, J.;

Both a PKS and a PPTase are involved in melanin biosynthesis and regulation of Aureobasidium melanogenum XJ5-1 isolated from the Taklimakan desert.

PubMed

Jiang, Hong; Liu, Guang-Lei; Chi, Zhe; Wang, Jian-Ming; Zhang, Ly-Ly; Chi, Zhen-Ming

2017-02-20

A PKS1 gene responsible for the melanin biosynthesis and a NPG1 gene in Aureobasidium melanogenum XJ5-1 were cloned and characterized. An ORF of the PKS1 gene encoding a protein with 2165 amino acids contained 6495bp while an ORF of the NPG1 gene encoding a protein with 340 amino acids had 1076bp. After analysis of their promoters, it was found that expression of both the PKS1 gene and the NPG1 gene was repressed by nitrogen sources and glucose, respectively. The PKS deduced from the cloned gene consisted of one ketosynthase, one acyl transferase, two acyl carrier proteins, one thioesterase and one cyclase while the PPTase belonged to the family Sfp-type. After disruption of the PKS1 gene and the NPG1 gene, expression of the PKS1 gene and the NPG1 gene and the melanin biosynthesis in the disruptants K5 and DP107 disappeared and expression of the PKS1 gene in the disruptant DP107 was also negatively influenced. However, after the NPG1 gene was complemented in the disruptant DP107, the melanin biosynthesis in the complementary strain BP17 was restored and expression of the PKS1 gene and the NPG1 gene was greatly enhanced, suggesting that the PKS was indeed activated and regulated by the PPTase and expression of the PKS1 gene and the NPG1 gene had a coordinate regulation. Copyright © 2016 Elsevier B.V. All rights reserved.

Fermi LAT Detection of a GeV Flare from FSRQ PKS 2320-035

NASA Astrophysics Data System (ADS)

Carpenter, Bryce; Ojha, Roopesh

2013-04-01

The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed increasing gamma-ray flux from a source positionally consistent with the flat spectrum radio quasar PKS 2320-035 (also known as 2FGL J2323.6-0316, Nolan et al. 2012, ApJS, 199, 31). PKS 2320-035 has coordinates RA=23h23m31.9537s DEC=-03d17m05.023s, J2000, (Johnston et al. 1995, AJ, 110, 880) and redshift z=1.41 (Browne et al.

PKS 2005-489 at VHE: four years of monitoring with HESS and simultaneous multi-wavelength observations

NASA Astrophysics Data System (ADS)

H.E.S.S. Collaboration; Acero, F.; Aharonian, F.; Akhperjanian, A. G.; Anton, G.; Barres de Almeida, U.; Bazer-Bachi, A. R.; Becherini, Y.; Behera, B.; Benbow, W.; Bernlöhr, K.; Bochow, A.; Boisson, C.; Bolmont, J.; Borrel, V.; Brucker, J.; Brun, F.; Brun, P.; Bühler, R.; Bulik, T.; Büsching, I.; Boutelier, T.; Chadwick, P. M.; Charbonnier, A.; Chaves, R. C. G.; Cheesebrough, A.; Chounet, L.-M.; Clapson, A. C.; Coignet, G.; Costamante, L.; Dalton, M.; Daniel, M. K.; Davids, I. D.; Degrange, B.; Deil, C.; Dickinson, H. J.; Djannati-Ataï, A.; Domainko, W.; O'C. Drury, L.; Dubois, F.; Dubus, G.; Dyks, J.; Dyrda, M.; Egberts, K.; Eger, P.; Espigat, P.; Fallon, L.; Farnier, C.; Fegan, S.; Feinstein, F.; Fiasson, A.; Förster, A.; Fontaine, G.; Füßling, M.; Gabici, S.; Gallant, Y. A.; Gérard, L.; Gerbig, D.; Giebels, B.; Glicenstein, J. F.; Glück, B.; Goret, P.; Göring, D.; Hauser, M.; Heinz, S.; Heinzelmann, G.; Henri, G.; Hermann, G.; Hinton, J. A.; Hoffmann, A.; Hofmann, W.; Hofverberg, P.; Holleran, M.; Hoppe, S.; Horns, D.; Jacholkowska, A.; de Jager, O. C.; Jahn, C.; Jung, I.; Katarzyński, K.; Katz, U.; Kaufmann, S.; Kerschhaggl, M.; Khangulyan, D.; Khélifi, B.; Keogh, D.; Klochkov, D.; Kluźniak, W.; Kneiske, T.; Komin, Nu.; Kosack, K.; Kossakowski, R.; Lamanna, G.; Lenain, J.-P.; Lohse, T.; Marandon, V.; Martineau-Huynh, O.; Marcowith, A.; Masbou, J.; Maurin, D.; McComb, T. J. L.; Medina, M. C.; Méhault, J.; Moderski, R.; Moulin, E.; Naumann-Godo, M.; de Naurois, M.; Nedbal, D.; Nekrassov, D.; Nicholas, B.; Niemiec, J.; Nolan, S. J.; Ohm, S.; Olive, J.-F.; de Oña Wilhelmi, E.; Orford, K. J.; Ostrowski, M.; Panter, M.; Paz Arribas, M.; Pedaletti, G.; Pelletier, G.; Petrucci, P.-O.; Pita, S.; Pühlhofer, G.; Punch, M.; Quirrenbach, A.; Raubenheimer, B. C.; Raue, M.; Rayner, S. M.; Renaud, M.; Rieger, F.; Ripken, J.; Rob, L.; Rosier-Lees, S.; Rowell, G.; Rudak, B.; Rulten, C. B.; Ruppel, J.; Sahakian, V.; Santangelo, A.; Schlickeiser, R.; Schöck, F. M.; Schwanke, U.; Schwarzburg, S.; Schwemmer, S.; Shalchi, A.; Sikora, M.; Skilton, J. L.; Sol, H.; Stawarz, Ł.; Steenkamp, R.; Stegmann, C.; Stinzing, F.; Superina, G.; Szostek, A.; Tam, P. H.; Tavernet, J.-P.; Terrier, R.; Tibolla, O.; Tluczykont, M.; van Eldik, C.; Vasileiadis, G.; Venter, C.; Venter, L.; Vialle, J. P.; Vincent, P.; Vivier, M.; Völk, H. J.; Volpe, F.; Wagner, S. J.; Ward, M.; Zdziarski, A. A.; Zech, A.

2010-02-01

Aims: Our aim is to study the very high energy (VHE; E>100 GeV) γ-ray emission from BL Lac objects and the evolution in time of their broad-band spectral energy distribution (SED). Methods: VHE observations of the high-frequency peaked BL Lac object PKS 2005-489 were made with the High Energy Stereoscopic System (HESS) from 2004 through 2007. Three simultaneous multi-wavelength campaigns at lower energies were performed during the HESS data taking, consisting of several individual pointings with the XMM-Newton and RXTE satellites. Results: A strong VHE signal, ~17σ total, from PKS 2005-489 was detected during the four years of HESS observations (90.3 h live time). The integral flux above the average analysis threshold of 400 GeV is ~3% of the flux observed from the Crab Nebula and varies weakly on time scales from days to years. The average VHE spectrum measured from ~300 GeV to ~5 TeV is characterized by a power law with a photon index, Γ = 3.20± 0.16_stat± 0.10_syst. At X-ray energies the flux is observed to vary by more than an order of magnitude between 2004 and 2005. Strong changes in the X-ray spectrum (ΔΓX ≈ 0.7) are also observed, which appear to be mirrored in the VHE band. Conclusions: The SED of PKS 2005-489, constructed for the first time with contemporaneous data on both humps, shows significant evolution. The large flux variations in the X-ray band, coupled with weak or no variations in the VHE band and a similar spectral behavior, suggest the emergence of a new, separate, harder emission component in September 2005. Supported by CAPES Foundation, Ministry of Education of Brazil.Now at Harvard-Smithsonian Center for Astrophysics, Cambridge, USA.Now at W.W. Hansen Experimental Physics Laboratory & Kavli Institute for Particle Astrophysics and Cosmology, Stanford University, Stanford, USA.

PKS 1830-211: A Possible Compound Gravitational Lens

NASA Technical Reports Server (NTRS)

Lovell, J. E. J.; Reynolds, J. E.; Jauncey, D. L.; Backus, P. R.; McCullock, P. M.; Sinclair, M. W.; Wilson, W. E.; Tzioumis, A. K.; Gough, R. G.; Ellingsen, S. P.;

The Arabidopsis Chaperone J3 Regulates the Plasma Membrane H+-ATPase through Interaction with the PKS5 Kinase[C][W

PubMed Central

Yang, Yongqing; Qin, Yunxia; Xie, Changgen; Zhao, Feiyi; Zhao, Jinfeng; Liu, Dafa; Chen, Shouyi; Fuglsang, Anja T.; Palmgren, Michael G.; Schumaker, Karen S.; Deng, Xing Wang; Guo, Yan

2010-01-01

The plasma membrane H+-ATPase (PM H+-ATPase) plays an important role in the regulation of ion and metabolite transport and is involved in physiological processes that include cell growth, intracellular pH, and stomatal regulation. PM H+-ATPase activity is controlled by many factors, including hormones, calcium, light, and environmental stresses like increased soil salinity. We have previously shown that the Arabidopsis thaliana Salt Overly Sensitive2-Like Protein Kinase5 (PKS5) negatively regulates the PM H+-ATPase. Here, we report that a chaperone, J3 (DnaJ homolog 3; heat shock protein 40-like), activates PM H+-ATPase activity by physically interacting with and repressing PKS5 kinase activity. Plants lacking J3 are hypersensitive to salt at high external pH and exhibit decreased PM H+-ATPase activity. J3 functions upstream of PKS5 as double mutants generated using j3-1 and several pks5 mutant alleles with altered kinase activity have levels of PM H+-ATPase activity and responses to salt at alkaline pH similar to their corresponding pks5 mutant. Taken together, our results demonstrate that regulation of PM H+-ATPase activity by J3 takes place via inactivation of the PKS5 kinase. PMID:20418496

Unusual flaring activity in the blazar PKS 1424-418 during 2008-2011

DOE PAGES

Buson, S.; Longo, F.; Larsson, S.; ...

2014-09-01

Context. Blazars are a subset of active galactic nuclei (AGN) with jets that are oriented along our line of sight. Variability and spectral energy distribution (SED) studies are crucial tools for understanding the physical processes responsible for observed AGN emission. Aims. We report peculiar behaviour in the bright γ-ray blazar PKS 1424-418 and use its strong variability to reveal information about the particle acceleration and interactions in the jet. Methods. Correlation analysis of the extensive optical coverage by the ATOM telescope and nearly continuous γ-ray coverage by the Fermi Large Area Telescope is combined with broadband, time-dependent modeling of themore » SED incorporating supplemental information from radio and X-ray observations of this blazar. Results. We analyse in detail four bright phases at optical-GeV energies. These flares of PKS 1424-418 show high correlation between these energy ranges, with the exception of one large optical flare that coincides with relatively low γ-ray activity. Although the optical/ γ-ray behaviour of PKS 1424-418 shows variety, the multiwavelength modeling indicates that these differences can largely be explained by changes in the flux and energy spectrum of the electrons in the jet that are radiating. We find that for all flares the SED is adequately represented by a leptonic model that includes inverse Compton emission from external radiation fields with similar parameters. Conclusions. Detailed studies of individual blazars like PKS 1424-418 during periods of enhanced activity in different wavebands are helping us identify underlying patterns in the physical parameters in this class of AGN.« less

Very high energy gamma-ray emission detected from PKS 1440-389 with H.E.S.S.

NASA Astrophysics Data System (ADS)

Hofmann, W.

2012-04-01

The BL Lac object PKS 1440-389, located at a tentative redshift of z=0.065 (6dF Galaxy Survey, Jones, D.H. et al. MNRAS 355, 747-763, 2004), has been reported as a hard (G=1.75+/-0.05), bright, and steady extragalactic source at GeV energies in the Fermi-LAT catalogue (2FGL J1443.9-3908, P.L. Nolan et al., 2012, ApJS, 199, 31). The extrapolation of the Fermi-LAT spectrum to very high energies (VHE; E> 100 GeV), together with its brightness in the radio and X-ray bands, makes this BL Lac object a good candidate for VHE emission.

Is the GeV-TeV emission of PKS 0447-439 from the proton synchrotron radiation?

NASA Astrophysics Data System (ADS)

Gao, Quan-Gui; Lu, Fang-Wu; Ma, Ju; Ren, Ji-Yang; Li, Huai-Zhen

2018-06-01

We study the multi-wavelength emission features of PKS 0447-439 in the frame of the one-zone homogeneous lepto-hadronic model. In this model, we assumed that the steady power-laws with exponential cut-offs distributions of protons and electrons are injected into the source. The non-linear time-dependent kinematic equations, describing the evolution of protons, electrons and photons, are defined; these equations self-consistently involve synchrotron radiation of protons, photon-photon interaction, synchrotron radiation of electron/positron pairs, inverse Compton scattering and synchrotron self-absorption. The model is applied to reproduce the multi-wavelength spectrum of PKS 0447-439. Our results indicate that the spectral energy distribution (SED) of PKS 0447-439 can be reproduced well by the model. In particular, the GeV-TeV emission is produced by the synchrotron radiation of relativistic protons. The physically plausible solutions require the magnetic strength 10 G≲ B ≲ 100 G. We found that the observed spectrum of PKS 0447-439 can be reproduced well by the model whether z = 0.16 or z = 0.2, and the acceptable upper limit of redshift is z=0.343.

Intergalactic Extinction of High Energy Gamma-Rays

NASA Technical Reports Server (NTRS)

Stecker, F. W.

1998-01-01

We discuss the determination of the intergalactic pair-production absorption coefficient as derived by Stecker and De Jager by making use of a new empirically based calculation of the spectral energy distribution of the intergalactic infrared radiation field as given by Malkan and Stecker. We show that the results of the Malkan and Stecker calculation agree well with recent data on the infrared background. We then show that Whipple observations of the flaring gamma-ray spectrum of Mrk 421 hint at extragalactic absorption and that the HEGRA observations of the flaring spectrum of Mrk 501 appear to strongly indicate extragalactic absorption. We also discuss the determination of the y-ray opacity at higher redshifts, following the treatment of Salamon and Stecker. We give a predicted spectrum, with absorption included for PKS 2155-304. This XBL lies at a redshift of 0.12, the highest redshift source yet observed at an energy above 0.3 TeV. This source should have its spectrum steepened by approx. 1 in its spectral index between approx. 0.3 and approx. 3 TeV and should show an absorption cutoff above approx. 6 TeV.

Unveiling the nature of the  $$\\gamma$$-ray emitting active galactic nucleus PKS 0521-36

DOE PAGES

D'Ammando, F.; Orienti, M.; Tavecchio, F.; ...

2015-05-19

PKS 0521-36 is an active galactic nucleus (AGN) with uncertain classification. Here, we investigate the properties of this source from radio to γ-rays. The broad emission lines in the optical and ultraviolet bands and steep radio spectrum indicate a possible classification as an intermediate object between broad-line radio galaxies (BLRG) and steep spectrum radio quasars (SSRQ). On pc-scales PKS 0521-36 shows a knotty structure similar to misaligned AGN. The core dominance and the γ-ray properties are similar to those estimated for other SSRQ and BLRG detected in γ-rays, suggesting an intermediate viewing angle with respect to the observer. In thismore » context the flaring activity detected from this source by Fermi-Large Area Telescope between 2010 June and 2012 February is very intriguing. We discuss the γ-ray emission of this source in the framework of the structured jet scenario, comparing the spectral energy distribution (SED) of the flaring state in 2010 June with that of a low state. We present three alternative models corresponding to three different choices of the viewing angles θv = 6°, 15°, and 20°. We obtain a good fit for the first two cases, but the SED obtained with θv = 15° if observed at a small angle does not resemble that of a typical blazar since the synchrotron emission should dominate by a large factor (~100) the inverse Compton component. This suggests that a viewing angle between 6° and 15° is preferred, with the rapid variability observed during γ-ray flares favouring a smaller angle. However, we cannot rule out that PKS 0521-36 is the misaligned counterpart of a synchrotron-dominated blazar.« less

PKS 2123-463: A Confirmed Gamma-ray Blazar at High Redshift

NASA Technical Reports Server (NTRS)

D'Ammando, F.; Rau, A.; Schady, P.; Finke, J.; Orienti, M.; Greiner, J.; Kann, D. A.; Ojha, R.; Foley, A. R.; Stevens, J.;

Fermi LAT detection of a GeV flare from the blazar PKS 0250-225

NASA Astrophysics Data System (ADS)

Dutka, Michael; Ojha, Roopesh

2012-11-01

The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed increasing gamma-ray flux from a source positionally consistent with the flat spectrum radio quasar PKS 0250-225 (also known as 2FGL J0252.7-2218, Nolan et al. 2012 ApJS, 199, 31). PKS 0250-225 has the coordinates RA=02h52m47.9536s, DEC=-22d19m25.465s, J2000, (Beasley et al. 2002 ApJS, 141, 13) and redshift z=1.419 (Shaw et al.

Fermi LAT detection of a new gamma-ray flare from FSRQ PKS 0502+049

NASA Astrophysics Data System (ADS)

Ojha, Roopesh; Dutka, Michael

2013-03-01

The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed increasing gamma-ray flux from a source positionally consistent with the flat spectrum radio quasar PKS 0502+049 (also known as 2FGL J0505.5+0501, Nolan et al. 2012 ApJS, 199, 31). PKS 0502+049 has coordinates RA=05h05m23.1847s DEC=+04d59m42.725s, J2000, (Johnston et al. 1995, AJ, 110, 880) and redshift z=0.954 (Drinkwater et al.

A ketoreductase domain in the PksJ protein of the bacillaene assembly line carries out both α- and β-ketone reduction during chain growth

PubMed Central

Calderone, Christopher T.; Bumpus, Stefanie B.; Kelleher, Neil L.; Walsh, Christopher T.; Magarvey, Nathan A.

2008-01-01

The polyketide signaling metabolites bacillaene and dihydrobacillaene are biosynthesized in Bacillus subtilis on an enzymatic assembly line with both nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) modules acting along with catalytic domains servicing the assembly line in trans. These signaling metabolites possess the unusual starter unit α-hydroxyisocaproate (α-HIC). We show here that it arises from initial activation of α-ketoisocaproate (α-KIC) by the first adenylation domain of PksJ (a hybrid PKS/NRPS) and installation on the pantetheinyl arm of the adjacent thiolation (T) domain. The α-KIC unit is elongated to α-KIC-Gly by the second NRPS module in PksJ as demonstrated by mass spectrometric analysis. The third module of PksJ uses PKS logic and contains an embedded ketoreductase (KR) domain along with two adjacent T domains. We show that this KR domain reduces canonical 3-ketobutyryl chains but also the α-keto group of α-KIC-containing intermediates on the PksJ T-domain doublet. This KR activity accounts for the α-HIC moiety found in the dihydrobacillaene/bacillaene pair and represents an example of an assembly-line dual-function α- and β-KR acting on disparate positions of a growing chain intermediate. PMID:18723688

Enhanced gamma-ray emission from the FSRQ PKS 0131-522

NASA Astrophysics Data System (ADS)

Piano, G.; Pittori, C.; Verrecchia, F.; Minervini, G.; Lucarelli, F.; Munar-Adrover, P.; Ursi, A.; Bulgarelli, A.; Fioretti, V.; Parmiggiani, N.; Tavani, M.; Donnarumma, I.; Vercellone, S.; Striani, E.; Cardillo, M.; Gianotti, F.; Trifoglio, M.; Giuliani, A.; Mereghetti, S.; Caraveo, P.; Perotti, F.; Chen, A.; Argan, A.; Costa, E.; Del Monte, E.; Evangelista, Y.; Feroci, M.; Lazzarotto, F.; Lapshov, I.; Pacciani, L.; Soffitta, P.; Sabatini, S.; Vittorini, V.; Pucella, G.; Rapisarda, M.; Di Cocco, G.; Fuschino, F.; Galli, M.; Labanti, C.; Marisaldi, M.; Pellizzoni, A.; Pilia, M.; Trois, A.; Barbiellini, G.; Vallazza, E.; Longo, F.; Morselli, A.; Picozza, P.; Prest, M.; Lipari, P.; Zanello, D.; Cattaneo, P. W.; Rappoldi, A.; Colafrancesco, S.; Ferrari, A.; Paoletti, F.; Antonelli, A.; Giommi, P.; Salotti, L.; Valentini, G.; D'Amico, F.

2017-11-01

AGILE is detecting enhanced gamma-ray emission above 100 MeV from the FSRQ PKS 0131-522 (z=0.02; also known as 3FGL J0133.2-5159), at Galactic coordinates (l, b) = (288.4, -63.8) +/- 0.6 deg (stat.) +/- 0.1 deg (sys.).

Interkingdom Gene Transfer of a Hybrid NPS/PKS from Bacteria to Filamentous Ascomycota

PubMed Central

Lawrence, Daniel P.; Kroken, Scott; Pryor, Barry M.; Arnold, A. Elizabeth

2011-01-01

Nonribosomal peptides (NRPs) and polyketides (PKs) are ecologically important secondary metabolites produced by bacteria and fungi using multidomain enzymes called nonribosomal peptide synthetases (NRPSs) and polyketide synthases (PKSs), respectively. Previous phylogenetic analyses of fungal NRPSs and PKSs have suggested that a few of these genes were acquired by fungi via horizontal gene transfer (HGT) from bacteria, including a hybrid NPS/PKS found in Cochliobolus heterostrophus (Dothideomycetes, Ascomycota). Here, we identify this hybrid gene in fungi representing two additional classes of Ascomycota (Aspergillus spp., Microsporum canis, Arthroderma spp., and Trichophyton spp., Eurotiomycetes; Chaetomium spp. and Metarhizium spp., Sordariomycetes) and use phylogenetic analyses of the most highly conserved domains from NRPSs (adenylation (A) domain) and PKSs (ketoacyl synthase (KS) domain) to examine the hypothesis that the hybrid NPS7/PKS24 was acquired by fungi from bacteria via HGT relatively early in the evolution of the Pezizomycotina. Our results reveal a unique ancestry of the A domain and KS domain in the hybrid gene relative to known fungal NRPSs and PKSs, provide strong evidence for HGT of the hybrid gene from a putative bacterial donor in the Burkholderiales, and suggest the HGT event occurred early in the evolution of the filamentous Ascomycota. PMID:22140558

Ketide Synthase (KS) Domain Prediction and Analysis of Iterative Type II PKS Gene in Marine Sponge-Associated Actinobacteria Producing Biosurfactants and Antimicrobial Agents

PubMed Central

Selvin, Joseph; Sathiyanarayanan, Ganesan; Lipton, Anuj N.; Al-Dhabi, Naif Abdullah; Valan Arasu, Mariadhas; Kiran, George S.

2016-01-01

The important biological macromolecules, such as lipopeptide and glycolipid biosurfactant producing marine actinobacteria were analyzed and their potential linkage between type II polyketide synthase (PKS) genes was explored. A unique feature of type II PKS genes is their high amino acid (AA) sequence homology and conserved gene organization. These enzymes mediate the biosynthesis of polyketide natural products with enormous structural complexity and chemical nature by combinatorial use of various domains. Therefore, deciphering the order of AA sequence encoded by PKS domains tailored the chemical structure of polyketide analogs still remains a great challenge. The present work deals with an in vitro and in silico analysis of PKS type II genes from five actinobacterial species to correlate KS domain architecture and structural features. Our present analysis reveals the unique protein domain organization of iterative type II PKS and KS domain of marine actinobacteria. The findings of this study would have implications in metabolic pathway reconstruction and design of semi-synthetic genomes to achieve rational design of novel natural products. PMID:26903957

Multiwavelength observations of a VHE gamma-ray flare from PKS 1510-089 in 2015

NASA Astrophysics Data System (ADS)

Ahnen, M. L.; Ansoldi, S.; Antonelli, L. A.; Arcaro, C.; Babić, A.; Banerjee, B.; Bangale, P.; Barres de Almeida, U.; Barrio, J. A.; Bednarek, W.; Bernardini, E.; Berti, A.; Biasuzzi, B.; Biland, A.; Blanch, O.; Bonnefoy, S.; Bonnoli, G.; Borracci, F.; Bretz, T.; Carosi, R.; Carosi, A.; Chatterjee, A.; Colin, P.; Colombo, E.; Contreras, J. L.; Cortina, J.; Covino, S.; Cumani, P.; Da Vela, P.; Dazzi, F.; De Angelis, A.; De Lotto, B.; de Oña Wilhelmi, E.; Di Pierro, F.; Doert, M.; Domínguez, A.; Dominis Prester, D.; Dorner, D.; Doro, M.; Einecke, S.; Eisenacher Glawion, D.; Elsaesser, D.; Engelkemeier, M.; Fallah Ramazani, V.; Fernández-Barral, A.; Fidalgo, D.; Fonseca, M. V.; Font, L.; Fruck, C.; Galindo, D.; García López, R. J.; Garczarczyk, M.; Gaug, M.; Giammaria, P.; Godinović, N.; Gora, D.; Guberman, D.; Hadasch, D.; Hahn, A.; Hassan, T.; Hayashida, M.; Herrera, J.; Hose, J.; Hrupec, D.; Hughes, G.; Ishio, K.; Konno, Y.; Kubo, H.; Kushida, J.; Kuveždić, D.; Lelas, D.; Lindfors, E.; Lombardi, S.; Longo, F.; López, M.; Majumdar, P.; Makariev, M.; Maneva, G.; Manganaro, M.; Mannheim, K.; Maraschi, L.; Mariotti, M.; Martínez, M.; Mazin, D.; Menzel, U.; Mirzoyan, R.; Moralejo, A.; Moretti, E.; Nakajima, D.; Neustroev, V.; Niedzwiecki, A.; Nievas Rosillo, M.; Nilsson, K.; Nishijima, K.; Noda, K.; Nogués, L.; Paiano, S.; Palacio, J.; Palatiello, M.; Paneque, D.; Paoletti, R.; Paredes, J. M.; Paredes-Fortuny, X.; Pedaletti, G.; Peresano, M.; Perri, L.; Persic, M.; Poutanen, J.; Prada Moroni, P. G.; Prandini, E.; Puljak, I.; Garcia, J. R.; Reichardt, I.; Rhode, W.; Ribó, M.; Rico, J.; Saito, T.; Satalecka, K.; Schroeder, S.; Schweizer, T.; Shore, S. N.; Sillanpää, A.; Sitarek, J.; Šnidarić, I.; Sobczynska, D.; Stamerra, A.; Strzys, M.; Surić, T.; Takalo, L.; Tavecchio, F.; Temnikov, P.; Terzić, T.; Tescaro, D.; Teshima, M.; Torres, D. F.; Torres-Albà, N.; Toyama, T.; Treves, A.; Vanzo, G.; Vazquez Acosta, M.; Vovk, I.; Ward, J. E.; Will, M.; Wu, M. H.; Zarić, D.; Desiante, R.; Becerra González, J.; D'Ammando, F.; Larsson, S.; Raiteri, C. M.; Reinthal, R.; Lähteenmäki, A.; Järvelä, E.; Tornikoski, M.; Ramakrishnan, V.; Jorstad, S. G.; Marscher, A. P.; Bala, V.; MacDonald, N. R.; Kaur, N.; Sameer; Baliyan, K.; Acosta-Pulido, J. A.; Lazaro, C.; Martí-nez-Lombilla, C.; Grinon-Marin, A. B.; Pastor Yabar, A.; Protasio, C.; Carnerero, M. I.; Jermak, H.; Steele, I. A.; Larionov, V. M.; Borman, G. A.; Grishina, T. S.

2017-07-01

Context. PKS 1510-089 is one of only a few flat spectrum radio quasars detected in the very-high-energy (VHE, > 100 GeV) gamma-ray band. Aims: We study the broadband spectral and temporal properties of the PKS 1510-089 emission during a high gamma-ray state. Methods: We performed VHE gamma-ray observations of PKS 1510-089 with the Major Atmospheric Gamma Imaging Cherenkov (MAGIC) telescopes during a long, high gamma-ray state in May 2015. In order to perform broadband modeling of the source, we have also gathered contemporaneous multiwavelength data in radio, IR, optical photometry and polarization, UV, X-ray, and GeV gamma-ray ranges. We construct a broadband spectral energy distribution (SED) in two periods, selected according to VHE gamma-ray state. Results: PKS 1510-089 was detected by MAGIC during a few day-long observations performed in the middle of a long, high optical and gamma-ray state, showing for the first time a significant VHE gamma-ray variability. Similarly to the optical and gamma-ray high state of the source detected in 2012, it was accompanied by a rotation of the optical polarization angle and the emission of a new jet component observed in radio. However, owing to large uncertainty on the knot separation time, the association with the VHE gamma-ray emission cannot be firmly established. The spectral shape in the VHE band during the flare is similar to those obtained during previous measurements of the source. The observed flux variability sets constraints for the first time on the size of the region from which VHE gamma rays are emitted. We model the broadband SED in the framework of the external Compton scenario and discuss the possible emission site in view of multiwavelength data and alternative emission models.

Examining the nature of very-high-energy gamma-ray emission from the AGN PKS 1222+216 and 3C 279

NASA Astrophysics Data System (ADS)

Price, Sharleen; Brill, Ari; Mukherjee, Reshmi; VERITAS

2018-01-01

Blazars are a type of active galactic nuclei (AGN) that emit jets of ionized matter which move towards the Earth at relativistic speeds. In this research we carried out a study of two objects, 3C 279 and PKS 1222+216, which belong to the subset of blazars known as FSRQs (flat spectrum radio quasars), the most powerful TeV-detected sources at gamma-ray energies with bolometric luminosities exceeding 1048 erg/s. The high-energy emission of quasars peaks in the MeV-GeV band, making these sources very rarely detectable in the TeV energy range. In fact, only six FSRQs have ever been detected in this range by very-high-energy gamma-ray telescopes. We will present results from observing campaigns on 3C 279 in 2014 and 2016, when the object was detected in high flux states by Fermi-LAT. Observations include simultaneous coverage with the Fermi-LAT satellite and the VERITAS ground-based array spanning four decades in energy from 100 MeV to 1 TeV. We will also report VERITAS observations of PKS 1222+216 between 2008 and 2017. The detection/non-detection of TeV emission during flaring episodes at MeV energies will further contribute to our understanding of particle acceleration and gamma-ray emission mechanisms in blazar jets.

Phylogeny and Expression Analyses Reveal Important Roles for Plant PKS III Family during the Conquest of Land by Plants and Angiosperm Diversification

PubMed Central

Xie, Lulu; Liu, Pingli; Zhu, Zhixin; Zhang, Shifan; Zhang, Shujiang; Li, Fei; Zhang, Hui; Li, Guoliang; Wei, Yunxiao; Sun, Rifei

2016-01-01

Polyketide synthases (PKSs) utilize the products of primary metabolism to synthesize a wide array of secondary metabolites in both prokaryotic and eukaryotic organisms. PKSs can be grouped into three distinct classes, types I, II, and III, based on enzyme structure, substrate specificity, and catalytic mechanisms. The type III PKS enzymes function as homodimers, and are the only class of PKS that do not require acyl carrier protein. Plant type III PKS enzymes, also known as chalcone synthase (CHS)-like enzymes, are of particular interest due to their functional diversity. In this study, we mined type III PKS gene sequences from the genomes of six aquatic algae and 25 land plants (1 bryophyte, 1 lycophyte, 2 basal angiosperms, 16 core eudicots, and 5 monocots). PKS III sequences were found relatively conserved in all embryophytes, but not exist in algae. We also examined gene expression patterns by analyzing available transcriptome data, and identified potential cis-regulatory elements in upstream sequences. Phylogenetic trees of dicots angiosperms showed that plant type III PKS proteins fall into three clades. Clade A contains CHS/STS-type enzymes coding genes with diverse transcriptional expression patterns and enzymatic functions, while clade B is further divided into subclades b1 and b2, which consist of anther-specific CHS-like enzymes. Differentiation regions, such as amino acids 196-207 between clades A and B, and predicted positive selected sites within α-helixes in late appeared branches of clade A, account for the major diversification in substrate choice and catalytic reaction. The integrity and location of conserved cis-elements containing MYB and bHLH binding sites can affect transcription levels. Potential binding sites for transcription factors such as WRKY, SPL, or AP2/EREBP may contribute to tissue- or taxon-specific differences in gene expression. Our data shows that gene duplications and functional diversification of plant type III PKS enzymes

The unique, optically-dominated quasar jet of PKS 1421-490

NASA Astrophysics Data System (ADS)

Gelbord, J. M.; Marshall, H. L.; Worrall, D. M.; Birkinshaw, M.; Lovell, J. E. J.; Ojha, R.; Godfrey, L.; Schwartz, D. A.; Perlman, E. S.; Georganopoulos, M.; Murphy, D. W.; Jauncey, D. L.

2004-12-01

The unique, optically-dominated quasar jet of PKS 1421-490 We report the discovery of extremely strong optical and X-ray emission associated with a knot in the radio jet of PKS 1421-490. The SDSS g' = 17.8 magnitude makes this the second-brightest optical jet known. The jet-to-core flux ratio in the X-ray band is unusually large (3.7), and the optical flux ratio ( ˜300) is unprecedented. The broad-band spectrum of the knot is flat from the radio through the optical bands, and has a similar slope with a lower normalization in the X-ray band. This emission is difficult to interpret without resorting to extreme model parameters or physically unlikely scenarios (flat electron distributions, non-equipartition magnetic fields, huge Doppler factors, etc.). We discuss several alternative models for the radio-to-X-ray continuum, including pure synchrotron, synchrotron plus inverse Compton scattering of cosmic microwave background photons, and a decelerating jet. JMG was supported under Chandra grant GO4-5124X to MIT from the CXC. HLM was supported under NASA contract SAO SV1-61010 for the Chandra X-Ray Center (CXC).

Involvement of a Polyketide Synthetase ClPKS18 in the Regulation of Vegetative Growth, Melanin and Toxin Synthesis, and Virulence in Curvularia lunata.

PubMed

Gao, Jin-Xin; Chen, Jie

2017-12-01

The clpks18 gene was first cloned and identified in Curvularia lunata. It contains 6571 base pairs (bp) and an 6276 bp open reading frame encoding 2091 amino acids. The ClPKS18 deletion mutant displayed an albino phenotype, and almost lost the ability to product 5-(hydroxymethyl) furan-2-carboxylate (M5HF2C) toxin, implying that clpks18 gene in C. lunata is not only involved in 1,8-dihydroxynaphthalene melanin synthesis, but also relatively associated with M5HF2C toxin biosynthesis of the pathogen. The pathogenicity assays revealed that ΔClPKS18 was impaired in colonizing the maize leaves, which corresponds to the finding that ClPKS18 controls the production of melanin and M5HF2C in C. lunata . Results indicate that ClPKS18 plays a vital role in regulating pathogenicity of in C. lunata .

48 CFR 6103.304 - Reply to the audit division and agency responses [Rule 304].

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Reply to the audit division and agency responses [Rule 304]. 6103.304 Section 6103.304 Federal Acquisition Regulations System CIVILIAN BOARD OF CONTRACT APPEALS, GENERAL SERVICES ADMINISTRATION TRANSPORTATION RATE CASES 6103.304 Reply to the audit division and agency...

Identification of PaPKS1, a polyketide synthase involved in melanin formation and its use as a genetic tool in Podospora anserina.

PubMed

Coppin, Evelyne; Silar, Philippe

2007-08-01

In the filamentous fungus Podospora anserina, many pigmentation mutations map to the median region of the complex locus '14', called segment '29'. The data presented in this paper show that segment 29 corresponds to a gene encoding a polyketide synthase, designated PaPKS1, and identifies two mutations that completely or partially abolish the activity of the PaPKS1 polypeptide. We present evidence that the P. anserina green pigment is a (DHN)-melanin. Using the powerful genetic system of PaPKS1 cloning, we demonstrate that in P. anserina trans-duplicated sequences are subject to the RIP process as previously demonstrated for the cis-duplicated regions.

Role of the pks15/1 gene in the biosynthesis of phenolglycolipids in the Mycobacterium tuberculosis complex. Evidence that all strains synthesize glycosylated p-hydroxybenzoic methyl esters and that strains devoid of phenolglycolipids harbor a frameshift mutation in the pks15/1 gene.

PubMed

Constant, Patricia; Perez, Esther; Malaga, Wladimir; Lanéelle, Marie-Antoinette; Saurel, Olivier; Daffé, Mamadou; Guilhot, Christophe

2002-10-11

Diesters of phthiocerol and phenolphthiocerol are important virulence factors of Mycobacterium tuberculosis and Mycobacterium leprae, the two main mycobacterial pathogens in humans. They are both long-chain beta-diols, and their biosynthetic pathway is beginning to be elucidated. Although the two classes of molecules share a common lipid core, phthiocerol diesters have been found in all the strains of the M. tuberculosis complex examined although phenolphthiocerol diesters are produced by only a few groups of strains. To address the question of the origin of this diversity 8 reference strains and 10 clinical isolates of M. tuberculosis were analyzed. We report the presence of glycosylated p-hydroxybenzoic acid methyl esters, structurally related to the type-specific phenolphthiocerol glycolipids, in the culture media of all reference strains of M. tuberculosis, suggesting that the strains devoid of phenolphthiocerol derivatives are unable to elongate the putative p-hydroxybenzoic acid precursor. We also show that all the strains of M. tuberculosis examined and deficient in the production of phenolphthiocerol derivatives are natural mutants with a frameshift mutation in pks15/1 whereas a single open reading frame for pks15/1 is found in Mycobacterium bovis BCG, M. leprae, and strains of M. tuberculosis that produce phenolphthiocerol derivatives. Complementation of the H37Rv strain of M. tuberculosis, which is devoid of phenolphthiocerol derivatives, with the fused pks15/1 gene from M. bovis BCG restored phenolphthiocerol glycolipids production. Conversely, disruption of the pks15/1 gene in M. bovis BCG led to the abolition of the synthesis of type-specific phenolphthiocerol glycolipid. These data indicate that Pks15/1 is involved in the elongation of p-hydroxybenzoic acid to give p-hydroxyphenylalkanoates, which in turn are converted, presumably by the PpsA-E synthase, to phenolphthiocerol derivatives.

Swift/XRT follow-up of the flaring blazar PKS 1424-41

NASA Astrophysics Data System (ADS)

D'Ammando, F.; Orienti, M.

2013-01-01

Following the optical and gamma-ray flaring activity of the flat spectrum radio quasar PKS 1424-41 (also known as 2FGL J1428.0-4206, Nolan et al. 2012, ApJS, 199, 31) detected by ATOM and Fermi LAT on 2013 January 6 (ATel #4714), a Swift target of opportunity observation was performed on January 7.

Swift follow-up of the flaring blazar PKS 0250-225

NASA Astrophysics Data System (ADS)

Dutka, Michael; Ojha, Roopesh; Donato, DavidePottschmidt, Katja

2012-11-01

Following the gamma-ray flaring activity of the flat spectrum radio quasar PKS 0250-225 (also known as 2FGL J0252.7-2218, Nolan et al. 2012, ApJS, 199, 31) detected by Fermi LAT on 2012 November 13 (ATel #4574) two Swift target of opportunity observations were performed on November 14 and 16. As no significant differences were found between the two epochs the combined results are reported here.

Multiwavelength observations of the gamma-ray blazar PKS 0528+134 in quiescence

DOE PAGES

Palma, N. I.; Böttcher, M.; de la Calle, I.; ...

2011-06-16

Here, we present multiwavelength observations of the ultraluminous blazar-type radio loud quasar PKS 0528+134 in quiescence during the period July to December 2009. Four Target-of-Opportunity (ToO) observations with the XMM-Newton Satellite in the 0.2 – 10 keV range were supplemented with optical observations.

Fermi LAT detection of GeV flares from blazars PKS 0458-02 and B2 1144+40

NASA Astrophysics Data System (ADS)

Antolini, Elisa; Buson, Sara

2014-03-01

The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed increasing gamma-ray flux from two sources positionally consistent with the flat spectrum radio quasars PKS 0458-02 (also known as 2FGL J0501.2-0155, Nolan et al. 2012 ApJS, 199, 31) and B2 1144+40 (also known as S4 1144+40 and 2FGL J1146.9+4000). PKS 0458-02 has the radio coordinates RA=05h01m12.8098s, Dec=-1d59m14.255s (J2000, Johnston et al.

50 CFR 300.304 - Prohibitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Prohibitions. 300.304 Section 300.304... Vessels on IUU Vessel Lists § 300.304 Prohibitions. (a) It is unlawful for a foreign, listed IUU vessel... arrangement with a listed IUU vessel. (d) The prohibitions listed in § 300.304(c) shall not apply when the...

48 CFR 1827.304 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Procedures. 1827.304 Section 1827.304 Federal Acquisition Regulations System NATIONAL AERONAUTICS AND SPACE ADMINISTRATION... 1827.304 Procedures. ...

Radial Profiles of PKS 0745-191 Galaxy Cluster with XMM-Newton X-Ray Observations

NASA Astrophysics Data System (ADS)

Tumer, A.; Ezer, C.; Ercan, E.

2017-10-01

Since clusters of galaxies are the largest comprehensive samples of the universe, they provide essential information on from the most basic to the most complex physical mechanisms such as nucleosynthesis and supernovae events. Some of these information are provided by the X-ray emission data from Intra Cluster Medium (ICM) which contains hot dilute gas. Recent archieved observation of the X-Ray spectrum of the cool core galaxy cluster PKS 0745-191 provided by XMM-Newton is subjected to data analysis using ESAS package. Followed by spectra analysis utilizing Xspec spectral fitting software, we present the radial profiles of temperature and abundance from the core to 0.5R_500 of brightest distant cluster (z ˜ 0.102) PKS 0745-191. Using the deprojected spectra, the radial distribution of pressure and entropy in the aforementioned region are also presented.

ALMA observations of AGN fuelling. The case of PKS B1718-649

NASA Astrophysics Data System (ADS)

Maccagni, F. M.; Morganti, R.; Oosterloo, T. A.; Oonk, J. B. R.; Emonts, B. H. C.

2018-06-01

We present ALMA observations of the 12CO (2-1) line of the newly born (tradio 102 years) active galactic nucleus (AGN), PKS B1718-649. These observations reveal that the carbon monoxide in the innermost 15 kpc of the galaxy is distributed in a complex warped disk. In the outer parts of this disk, the CO gas follows the rotation of the dust lane and of the stellar body of the galaxy hosting the radio source. In the innermost kiloparsec, the gas abruptly changes orientation and forms a circumnuclear disk (r ≲ 700 pc) with its major axis perpendicular to that of the outer disk. Against the compact radio emission of PKS B1718-649 (r 2 pc), we detect an absorption line at red-shifted velocities with respect to the systemic velocity (Δv = +365 ± 22 km s-1). This absorbing CO gas could trace molecular clouds falling onto the central super-massive black hole. A comparison with the near-infrared H2 1-0 S(1) observations shows that the clouds must be close to the black hole (r ≲ 75 pc). The physical conditions of these clouds are different from the gas at larger radii, and are in good agreement with the predictions for the conditions of the gas when cold chaotic accretion triggers an active galactic nucleus. These observations on the centre of PKS B1718-649 provide one of the best indications that a population of cold clouds is falling towards a radio AGN, likely fuelling its activity. The reduced datacube is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/614/A42

Crystallization and preliminary X-ray diffraction studies of polyketide synthase-1 (PKS-1) from Cannabis sativa

DOE Office of Scientific and Technical Information (OSTI.GOV)

Taguchi, Chiho; Quantum Beam Science Directorate, Japan Atomic Energy Agency; Taura, Futoshi

Polyketide synthase-1 from C. sativa has been crystallized. The crystal diffracted to 1.55 Å resolution with sufficient quality for further structure determination. Polyketide synthase-1 (PKS-1) is a novel type III polyketide synthase that catalyzes the biosynthesis of hexanoyl triacetic acid lactone in Cannabis sativa (Mexican strain). PKS-1 was overproduced in Escherichia coli, purified and finally crystallized in two different space groups. The crystal obtained in 0.1 M HEPES buffer pH 7.5 containing 0.2 M calcium acetate and 20%(w/v) polyethylene glycol 3350 diffracted to 1.65 Å resolution and belonged to space group P1, with unit-cell parameters a = 54.3, b =more » 59.3, c = 62.6 Å, α = 69, β = 81, γ = 80°. Another crystal obtained in 0.1 M HEPES buffer pH 7.5 containing 0.2 M sodium chloride and 20%(w/v) polyethylene glycol 3350 diffracted to 1.55 Å resolution and belonged to space group P2{sub 1}2{sub 1}2{sub 1}, with unit-cell parameters a = 54.3, b = 110, c = 130 Å. These data will enable us to determine the crystal structure of PKS-1.« less

The Gamma-Ray Emitting Radio-Loud Narrow-Line Seyfert 1 Galaxy PKS 2004-447 II. The Radio View

NASA Technical Reports Server (NTRS)

Schulz, R.; Kreikenbohm, A.; Kadler, M.; Ojha, R.; Ros, E.; Stevens, J.; Edwards, P. G.; Carpenter, B.; Elsaesser, D.; Gehrels, N.;

High radio fluxes of PKS2023-07 measured with RATAN-600

NASA Astrophysics Data System (ADS)

Trushkin, S. A.; Nizhelskij, N. A.; Tsybulev, P. G.

2016-04-01

After the AGILE detection the gamma-ray flare from the quasar PSK2023-07 (correctly PKS B2022-077) by Piano et al, ATel #8879 we carried out its observations with the RATAN-600 radio telescope SAO RAS. The measured flux densities are equal to 1.50, 1.96, 2.54 Jy at 4.8, 11.2, 21.7 GHz respectively on 1 Apr 2016.

45 CFR 304.95 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false [Reserved] 304.95 Section 304.95 Public Welfare Regulations Relating to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT (CHILD SUPPORT ENFORCEMENT PROGRAM... § 304.95 [Reserved] ...

45 CFR 304.27 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false [Reserved] 304.27 Section 304.27 Public Welfare Regulations Relating to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT (CHILD SUPPORT ENFORCEMENT PROGRAM... § 304.27 [Reserved] ...

48 CFR 932.304 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Procedures. 932.304 Section 932.304 Federal Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Loan Guarantees for Defense Production 932.304 Procedures. ...

48 CFR 32.304 - Procedures.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Procedures. 32.304 Section 32.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Loan Guarantees for Defense Production 32.304 Procedures. ...

48 CFR 1432.304 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Procedures. 1432.304 Section 1432.304 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL CONTRACTING REQUIREMENTS CONTRACT FINANCING Loan Guarantees for Defense Production 1432.304 Procedures. ...

48 CFR 13.304 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false [Reserved] 13.304 Section 13.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACTING METHODS AND CONTRACT TYPES SIMPLIFIED ACQUISITION PROCEDURES Simplified Acquisition Methods 13.304 [Reserved] ...

48 CFR 1227.304 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Procedures. 1227.304 Section 1227.304 Federal Acquisition Regulations System DEPARTMENT OF TRANSPORTATION GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 1227.304 Procedures. ...

48 CFR 1327.304 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Procedures. 1327.304 Section 1327.304 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 1327.304 Procedures. ...

48 CFR 27.304 - Procedures.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Procedures. 27.304 Section 27.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights under Government Contracts 27.304 Procedures. ...

48 CFR 627.304 - Procedures.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Procedures. 627.304 Section 627.304 Federal Acquisition Regulations System DEPARTMENT OF STATE GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 627.304 Procedures. ...

23 CFR 450.304 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 23 Highways 1 2012-04-01 2012-04-01 false Definitions. 450.304 Section 450.304 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Metropolitan Transportation Planning and Programming § 450.304 Definitions. Except as otherwise...

23 CFR 450.304 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 23 Highways 1 2013-04-01 2013-04-01 false Definitions. 450.304 Section 450.304 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Metropolitan Transportation Planning and Programming § 450.304 Definitions. Except as otherwise...

23 CFR 450.304 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 23 Highways 1 2014-04-01 2014-04-01 false Definitions. 450.304 Section 450.304 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Metropolitan Transportation Planning and Programming § 450.304 Definitions. Except as otherwise...

49 CFR 1016.304 - Reply.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 8 2011-10-01 2011-10-01 false Reply. 1016.304 Section 1016.304 Transportation... BOARD ADJUDICATORY PROCEEDINGS Procedures for Considering Applications § 1016.304 Reply. Within 15 days... supporting affidavits or a request for further proceedings under § 1016.307. ...

49 CFR 1016.304 - Reply.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 8 2010-10-01 2010-10-01 false Reply. 1016.304 Section 1016.304 Transportation... BOARD ADJUDICATORY PROCEEDINGS Procedures for Considering Applications § 1016.304 Reply. Within 15 days... supporting affidavits or a request for further proceedings under § 1016.307. ...

48 CFR 927.304 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Procedures. 927.304 Section 927.304 Federal Acquisition Regulations System DEPARTMENT OF ENERGY GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts 927.304 Procedures. Where...

48 CFR 1427.304 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Procedures. 1427.304 Section 1427.304 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR GENERAL CONTRACTING REQUIREMENTS PATENTS, DATA, AND COPYRIGHTS Patent Rights Under Government Contracts. 1427.304 Procedures. ...

48 CFR 304.602 - General.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false General. 304.602 Section 304.602 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATIVE MATTERS Contract Reporting 304.602 General. HHS' Departmental Contracts Information System (DCIS) captures...

48 CFR 9.304 - Exceptions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Exceptions. 9.304 Section 9.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS First Article Testing and Approval 9.304 Exceptions. Normally, testing and approval...

23 CFR 450.304 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 23 Highways 1 2010-04-01 2010-04-01 false Definitions. 450.304 Section 450.304 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Metropolitan Transportation Planning and Programming § 450.304 Definitions. Except as otherwise...

23 CFR 450.304 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 23 Highways 1 2011-04-01 2011-04-01 false Definitions. 450.304 Section 450.304 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION PLANNING AND RESEARCH PLANNING ASSISTANCE AND STANDARDS Metropolitan Transportation Planning and Programming § 450.304 Definitions. Except as otherwise...

7 CFR 1205.304 - Cotton.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false Cotton. 1205.304 Section 1205.304 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE COTTON RESEARCH AND PROMOTION Cotton Research and Promotion Order Definitions § 1205.304 Cotton. Cotton means: (a) All Upland cotton harvested...

7 CFR 1205.304 - Cotton.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 10 2013-01-01 2013-01-01 false Cotton. 1205.304 Section 1205.304 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE COTTON RESEARCH AND PROMOTION Cotton Research and Promotion Order Definitions § 1205.304 Cotton. Cotton means: (a) All Upland cotton harvested...

7 CFR 1205.304 - Cotton.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Cotton. 1205.304 Section 1205.304 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE COTTON RESEARCH AND PROMOTION Cotton Research and Promotion Order Definitions § 1205.304 Cotton. Cotton means: (a) All Upland cotton harvested...

7 CFR 1205.304 - Cotton.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Cotton. 1205.304 Section 1205.304 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE COTTON RESEARCH AND PROMOTION Cotton Research and Promotion Order Definitions § 1205.304 Cotton. Cotton means: (a) All Upland cotton harvested...

7 CFR 1205.304 - Cotton.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 10 2012-01-01 2012-01-01 false Cotton. 1205.304 Section 1205.304 Agriculture... AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE COTTON RESEARCH AND PROMOTION Cotton Research and Promotion Order Definitions § 1205.304 Cotton. Cotton means: (a) All Upland cotton harvested...

40 CFR 82.304 - Prohibitions.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 18 2014-07-01 2014-07-01 false Prohibitions. 82.304 Section 82.304 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PROTECTION OF STRATOSPHERIC OZONE Ban on Refrigeration and Air-Conditioning Appliances Containing HCFCs § 82.304 Prohibitions...

40 CFR 82.304 - Prohibitions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 18 2013-07-01 2013-07-01 false Prohibitions. 82.304 Section 82.304 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PROTECTION OF STRATOSPHERIC OZONE Ban on Refrigeration and Air-Conditioning Appliances Containing HCFCs § 82.304 Prohibitions...

40 CFR 82.304 - Prohibitions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 18 2012-07-01 2012-07-01 false Prohibitions. 82.304 Section 82.304 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PROTECTION OF STRATOSPHERIC OZONE Ban on Refrigeration and Air-Conditioning Appliances Containing HCFCs § 82.304 Prohibitions...

40 CFR 82.304 - Prohibitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 17 2011-07-01 2011-07-01 false Prohibitions. 82.304 Section 82.304 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PROTECTION OF STRATOSPHERIC OZONE Ban on Refrigeration and Air-Conditioning Appliances Containing HCFCs § 82.304 Prohibitions...

40 CFR 82.304 - Prohibitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Prohibitions. 82.304 Section 82.304 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) PROTECTION OF STRATOSPHERIC OZONE Ban on Refrigeration and Air-Conditioning Appliances Containing HCFCs § 82.304 Prohibitions...

44 CFR 304.4 - Allocations.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Allocations. 304.4 Section 304.4 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS CONSOLIDATED GRANTS TO INSULAR AREAS § 304.4 Allocations. For each Federal fiscal...

40 CFR 304.10 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 27 2010-07-01 2010-07-01 false Purpose. 304.10 Section 304.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND... § 304.10 Purpose. This regulation establishes and governs procedures for the arbitration of EPA cost...

7 CFR 1210.304 - Board.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Board. 1210.304 Section 1210.304 Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS... PLAN Watermelon Research and Promotion Plan Definitions § 1210.304 Board. Board means the National...

48 CFR 304.7100 - Policy.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Policy. 304.7100 Section 304.7100 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATIVE MATTERS Review and Approval of Proposed Contract Actions 304.7100 Policy. (a) The HCA (non-delegable...

44 CFR 304.2 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Definitions. 304.2 Section 304.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS CONSOLIDATED GRANTS TO INSULAR AREAS § 304.2 Definitions. Except as otherwise stated...

48 CFR 244.304 - Surveillance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Surveillance. 244.304 Section 244.304 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT... Reviews 244.304 Surveillance. (b) The ACO, or the purchasing system analyst (PSA) with the concurrence of...

5 CFR 304.101 - Coverage.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Coverage. 304.101 Section 304.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EXPERT AND CONSULTANT APPOINTMENTS § 304.101 Coverage. These regulations apply to the appointment of experts and consultants as...

5 CFR 304.101 - Coverage.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Coverage. 304.101 Section 304.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EXPERT AND CONSULTANT APPOINTMENTS § 304.101 Coverage. These regulations apply to the appointment of experts and consultants as...

5 CFR 304.101 - Coverage.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Coverage. 304.101 Section 304.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EXPERT AND CONSULTANT APPOINTMENTS § 304.101 Coverage. These regulations apply to the appointment of experts and consultants as...

5 CFR 304.101 - Coverage.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Coverage. 304.101 Section 304.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EXPERT AND CONSULTANT APPOINTMENTS § 304.101 Coverage. These regulations apply to the appointment of experts and consultants as...

5 CFR 304.101 - Coverage.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Coverage. 304.101 Section 304.101 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EXPERT AND CONSULTANT APPOINTMENTS § 304.101 Coverage. These regulations apply to the appointment of experts and consultants as...

17 CFR 229.304 - (Item 304) Changes in and disagreements with accountants on accounting and financial disclosure.

Code of Federal Regulations, 2014 CFR

2014-04-01

... disagreements with accountants on accounting and financial disclosure. 229.304 Section 229.304 Commodity and...-REGULATION S-K Financial Information § 229.304 (Item 304) Changes in and disagreements with accountants on... subsequent interim period, an independent accountant who was previously engaged as the principal accountant...

17 CFR 229.304 - (Item 304) Changes in and disagreements with accountants on accounting and financial disclosure.

Code of Federal Regulations, 2011 CFR

2011-04-01

... disagreements with accountants on accounting and financial disclosure. 229.304 Section 229.304 Commodity and...-REGULATION S-K Financial Information § 229.304 (Item 304) Changes in and disagreements with accountants on... subsequent interim period, an independent accountant who was previously engaged as the principal accountant...

17 CFR 229.304 - (Item 304) Changes in and disagreements with accountants on accounting and financial disclosure.

Code of Federal Regulations, 2012 CFR

2012-04-01

... disagreements with accountants on accounting and financial disclosure. 229.304 Section 229.304 Commodity and...-REGULATION S-K Financial Information § 229.304 (Item 304) Changes in and disagreements with accountants on... subsequent interim period, an independent accountant who was previously engaged as the principal accountant...

17 CFR 229.304 - (Item 304) Changes in and disagreements with accountants on accounting and financial disclosure.

Code of Federal Regulations, 2013 CFR

2013-04-01

... disagreements with accountants on accounting and financial disclosure. 229.304 Section 229.304 Commodity and...-REGULATION S-K Financial Information § 229.304 (Item 304) Changes in and disagreements with accountants on... subsequent interim period, an independent accountant who was previously engaged as the principal accountant...

Discovery of very high energy gamma rays from PKS 1424+240 and multiwavelength constraints on its redshift

DOE PAGES

Acciari, V. A.; Aliu, E.; Arlen, T.; ...

2009-12-18

Here, we report the first detection of very high energy 83Gamma-ray emission above 100 GeV. (VHE) gamma-ray emission above 140 GeV from PKS 1424+240, a BL Lac object with an unknown redshift. The photon spectrum above 140 GeV measured by VERITAS is well described by a power law with a photon index of 3.8 ± 0.5 stat ± 0.3 syst and a flux normalization at 200 GeV of (5.1 ± 0.9 stat ± 0.5 syst) × 10 –11 TeV –1 cm –2 s –1, where stat and syst denote the statistical and systematical uncertainties, respectively. The VHE flux is steadymore » over the observation period between MJD 54881 and 55003 (from 2009 February 19 to June 21). Flux variability is also not observed in contemporaneous high-energy observations with the Fermi Large Area Telescope. Contemporaneous X-ray and optical data were also obtained from the Swift XRT and MDM observatory, respectively. The broadband spectral energy distribution is well described by a one-zone synchrotron self-Compton model favoring a redshift of less than 0.1. We can conclude after using the photon index measured with Fermi in combination with recent extragalactic background light absorption models that the VERITAS data has a redshift of PKS 1424+240 less than 0.66.« less

28 CFR 24.304 - Settlement.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Settlement. 24.304 Section 24.304... DEPARTMENT OF JUSTICE ADMINISTRATIVE PROCEEDINGS Procedures for Considering Applications § 24.304 Settlement. A prevailing party and Department counsel may agree on a proposed settlement of an award before...

31 CFR 537.304 - Entity.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Entity. 537.304 Section 537.304 Money... CONTROL, DEPARTMENT OF THE TREASURY BURMESE SANCTIONS REGULATIONS General Definitions § 537.304 Entity. The term entity means a partnership, association, trust, joint venture, corporation, group, subgroup...

31 CFR 537.304 - Entity.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Entity. 537.304 Section 537.304 Money... CONTROL, DEPARTMENT OF THE TREASURY BURMESE SANCTIONS REGULATIONS General Definitions § 537.304 Entity. The term entity means a partnership, association, trust, joint venture, corporation, group, subgroup...

5 CFR 2610.304 - Reply.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Reply. 2610.304 Section 2610.304 Administrative Personnel OFFICE OF GOVERNMENT ETHICS ORGANIZATION AND PROCEDURES IMPLEMENTATION OF THE EQUAL ACCESS TO JUSTICE ACT Procedures for Considering Applications § 2610.304 Reply. Within 15 days after...

7 CFR 1942.304 - Definitions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 13 2011-01-01 2009-01-01 true Definitions. 1942.304 Section 1942.304 Agriculture Regulations of the Department of Agriculture (Continued) RURAL HOUSING SERVICE, RURAL BUSINESS-COOPERATIVE... § 1942.304 Definitions. Project. For rural business enterprise grants, the result of the use of program...

16 CFR 304.3 - Applicability.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Applicability. 304.3 Section 304.3 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS RULES AND REGULATIONS UNDER THE HOBBY PROTECTION ACT § 304.3 Applicability. Any person engaged in the manufacturing, or...

5 CFR 610.304 - Coverage.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Coverage. 610.304 Section 610.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS HOURS OF DUTY Administrative Dismissals of Daily, Hourly, and Piecework Employees § 610.304 Coverage. This subpart applies to regular...

5 CFR 610.304 - Coverage.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Coverage. 610.304 Section 610.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS HOURS OF DUTY Administrative Dismissals of Daily, Hourly, and Piecework Employees § 610.304 Coverage. This subpart applies to regular...

5 CFR 610.304 - Coverage.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Coverage. 610.304 Section 610.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS HOURS OF DUTY Administrative Dismissals of Daily, Hourly, and Piecework Employees § 610.304 Coverage. This subpart applies to regular...

5 CFR 610.304 - Coverage.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Coverage. 610.304 Section 610.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS HOURS OF DUTY Administrative Dismissals of Daily, Hourly, and Piecework Employees § 610.304 Coverage. This subpart applies to regular...

5 CFR 610.304 - Coverage.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Coverage. 610.304 Section 610.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS HOURS OF DUTY Administrative Dismissals of Daily, Hourly, and Piecework Employees § 610.304 Coverage. This subpart applies to regular...

31 CFR 551.304 - Interest.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Interest. 551.304 Section 551.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY SOMALIA SANCTIONS REGULATIONS General Definitions § 551.304...

14 CFR 1245.304 - Procedures.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 5 2011-01-01 2010-01-01 true Procedures. 1245.304 Section 1245.304 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PATENTS AND OTHER INTELLECTUAL PROPERTY RIGHTS NASA Foreign Patent Program § 1245.304 Procedures. (a) The patent counsel at each NASA field...

14 CFR 1245.304 - Procedures.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Procedures. 1245.304 Section 1245.304 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PATENTS AND OTHER INTELLECTUAL PROPERTY RIGHTS NASA Foreign Patent Program § 1245.304 Procedures. (a) The patent counsel at each NASA field...

30 CFR 585.304 - [Reserved

Code of Federal Regulations, 2012 CFR

2012-07-01

... 30 Mineral Resources 2 2012-07-01 2012-07-01 false [Reserved] 585.304 Section 585.304 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND... and Easement Grants for Renewable Energy Activities Row Grants and Rue Grants § 585.304 [Reserved...

30 CFR 585.304 - [Reserved

Code of Federal Regulations, 2014 CFR

2014-07-01

... 30 Mineral Resources 2 2014-07-01 2014-07-01 false [Reserved] 585.304 Section 585.304 Mineral Resources BUREAU OF OCEAN ENERGY MANAGEMENT, DEPARTMENT OF THE INTERIOR OFFSHORE RENEWABLE ENERGY AND... and Easement Grants for Renewable Energy Activities Row Grants and Rue Grants § 585.304 [Reserved...

31 CFR 546.304 - Entity.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Entity. 546.304 Section 546.304 Money... CONTROL, DEPARTMENT OF THE TREASURY DARFUR SANCTIONS REGULATIONS General Definitions § 546.304 Entity. The term entity means a partnership, association, trust, joint venture, corporation, group, subgroup, or...

31 CFR 576.304 - Entity.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Entity. 576.304 Section 576.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS... Definitions § 576.304 Entity. The term entity means a partnership, association, trust, joint venture...

31 CFR 546.304 - Entity.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Entity. 546.304 Section 546.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY DARFUR SANCTIONS REGULATIONS General Definitions § 546.304 Entity. The...

44 CFR 304.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Purpose. 304.1 Section 304.1 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS CONSOLIDATED GRANTS TO INSULAR AREAS § 304.1 Purpose. The purpose of the regulations in this part...

14 CFR 1209.304 - Membership.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Membership. 1209.304 Section 1209.304 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION BOARDS AND COMMITTEES Contract Adjustment Board § 1209.304 Membership. The Board will consist of a chairperson and four other members, all of whom...

22 CFR 304.5 - Investigations.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Investigations. 304.5 Section 304.5 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.5 Investigations. The Peace Corps may investigate, or the General Counsel may request any other Federal agency to...

22 CFR 304.5 - Investigations.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Investigations. 304.5 Section 304.5 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.5 Investigations. The Peace Corps may investigate, or the General Counsel may request any other Federal agency to...

5 CFR 304.103 - Authority.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Authority. 304.103 Section 304.103... APPOINTMENTS § 304.103 Authority. (a) Basic authority. (1) When authorized by an appropriation or other statute... expert or consultant who works on a strictly intermittent basis may be appointed under this authority...

5 CFR 304.107 - Reports.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Reports. 304.107 Section 304.107 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EXPERT AND CONSULTANT APPOINTMENTS § 304.107 Reports. As required by 5 U.S.C. 3109(e), each agency shall report to the Office of...

5 CFR 304.107 - Reports.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Reports. 304.107 Section 304.107 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EXPERT AND CONSULTANT APPOINTMENTS § 304.107 Reports. As required by 5 U.S.C. 3109(e), each agency shall report to the Office of...

5 CFR 304.107 - Reports.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Reports. 304.107 Section 304.107 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EXPERT AND CONSULTANT APPOINTMENTS § 304.107 Reports. As required by 5 U.S.C. 3109(e), each agency shall report to the Office of...

5 CFR 304.107 - Reports.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Reports. 304.107 Section 304.107 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS EXPERT AND CONSULTANT APPOINTMENTS § 304.107 Reports. As required by 5 U.S.C. 3109(e), each agency shall report to the Office of...

Performance Characteristics of 1977 American Motors 304 CID Engine

DOT National Transportation Integrated Search

1980-02-01

Experimental data were obtained in dynamometer tests of a 1977 AM 304 CID engine to determine fuel consumption and emissions (hydrocarbons, carbon monoxide, and oxides of nitrogen) at steady-state engine operating modes. The objective of the test was...

21 CFR 522.304 - Carprofen.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Carprofen. 522.304 Section 522.304 Food and Drugs..., AND RELATED PRODUCTS IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS § 522.304 Carprofen. (a) Specifications. Each milliliter of solution contains 50 milligrams (mg) carprofen. (b) Sponsor. See No. 000069 in...

21 CFR 522.304 - Carprofen.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 21 Food and Drugs 6 2013-04-01 2013-04-01 false Carprofen. 522.304 Section 522.304 Food and Drugs..., AND RELATED PRODUCTS IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS § 522.304 Carprofen. (a) Specifications. Each milliliter of solution contains 50 milligrams (mg) carprofen. (b) Sponsor. See No. 000069 in...

21 CFR 522.304 - Carprofen.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 21 Food and Drugs 6 2014-04-01 2014-04-01 false Carprofen. 522.304 Section 522.304 Food and Drugs..., AND RELATED PRODUCTS IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS § 522.304 Carprofen. (a) Specifications. Each milliliter of solution contains 50 milligrams (mg) carprofen. (b) Sponsor. See No. 054771 in...

21 CFR 522.304 - Carprofen.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 21 Food and Drugs 6 2012-04-01 2012-04-01 false Carprofen. 522.304 Section 522.304 Food and Drugs..., AND RELATED PRODUCTS IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS § 522.304 Carprofen. (a) Specifications. Each milliliter of solution contains 50 milligrams (mg) carprofen. (b) Sponsor. See No. 000069 in...

21 CFR 522.304 - Carprofen.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Carprofen. 522.304 Section 522.304 Food and Drugs..., AND RELATED PRODUCTS IMPLANTATION OR INJECTABLE DOSAGE FORM NEW ANIMAL DRUGS § 522.304 Carprofen. (a) Specifications. Each milliliter of solution contains 50 milligrams (mg) carprofen. (b) Sponsor. See No. 000069 in...

10 CFR 800.304 - Default.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Default. 800.304 Section 800.304 Energy DEPARTMENT OF ENERGY LOANS FOR BID OR PROPOSAL PREPARATION BY MINORITY BUSINESS ENTERPRISES SEEKING DOE CONTRACTS AND ASSISTANCE Loan Administration § 800.304 Default. (a) In the event that the borrower fails to perform the...

12 CFR 304.3 - Reports.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 12 Banks and Banking 5 2012-01-01 2012-01-01 false Reports. 304.3 Section 304.3 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE FORMS, INSTRUCTIONS, AND REPORTS § 304.3 Reports. (a) Consolidated Reports of Condition and Income, Forms FFIEC 031 and 041. Pursuant to...

12 CFR 304.3 - Reports.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Reports. 304.3 Section 304.3 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE FORMS, INSTRUCTIONS, AND REPORTS § 304.3 Reports. (a) Consolidated Reports of Condition and Income, Forms FFIEC 031 and 041. Pursuant to...

12 CFR 304.3 - Reports.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 5 2013-01-01 2013-01-01 false Reports. 304.3 Section 304.3 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE FORMS, INSTRUCTIONS, AND REPORTS § 304.3 Reports. (a) Consolidated Reports of Condition and Income, Forms FFIEC 031 and 041. Pursuant to...

12 CFR 304.3 - Reports.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 12 Banks and Banking 5 2014-01-01 2014-01-01 false Reports. 304.3 Section 304.3 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION PROCEDURE AND RULES OF PRACTICE FORMS, INSTRUCTIONS, AND REPORTS § 304.3 Reports. (a) Consolidated Reports of Condition and Income, Forms FFIEC 031 and 041. Pursuant to...

Multi-wavelength observations of PKS 2142-75 during active and quiescent gamma-ray states

DOE Office of Scientific and Technical Information (OSTI.GOV)

Dutka, Michael S.; Ojha, Roopesh; Pottschmidt, Katja

2013-12-04

Here, PKS 2142–75 (a.k.a. 2FGL J2147.4–7534) is a flat-spectrum radio quasar that was observed quasi-simultaneously by a suite of instruments across the electromagnetic spectrum during two flaring states in 2010 April and 2011 August as well as a quiescent state from 2011 December through 2012 January. The results of these campaigns and model spectral energy distributions (SEDs) from the active and quiescent states are presented. The SED model parameters of PKS 2142–75 indicate that the two flares of the source are created by unique physical conditions. SED studies of flat-spectrum radio quasars are beginning to indicate that there might bemore » two types of flares, those that can be described purely by changes in the electron distribution and those that require changes in other parameters, such as the magnetic field strength or the size of the emitting region.« less

An Intriguing Convex Break in the EGRET SED of Mrk 421

NASA Technical Reports Server (NTRS)

Nandikotkur, Giridhar; Jahoda, Keith M.; Georganopoulos, M.; Hartman, R. C.; Mukherjee, R.; Thompson, D. J.; Swank, Jean H.

2007-01-01

Based upon analysis of the entire EGRET data from Mrk 421, it is found that the time-averaged spectra are inconsistent with the predictions of current theoretical models that have had success in describing simultaneous X-ray/TeV observations, and suggest additional components in the GeV band, as well as complex time variability. Current theoretical pictures explain the GeV emission as comptonization of the synchrotron photons in the jet, and predict hard spectra that should join smoothly with the TeV emission. Our analysis shows that the situation is more complex. The spectrum ranges from hard to soft during individual epochs, and shows a convext break in the aggregated data. We also present the mission-averaged EGRET spectrum for PKS 2155-304, which shows a similar (but not as pronounced) convex curvature. We discuss a series of possible explanations for the 10(exp 22) - 10(exp 23) HZ declining part of the EGRET nu F(sub nu), spectrum for Mrk 421, and suggest that it is synchrotron emission from the high energy tail of the electron population that produces the X-rays during the highest X-ray states. Such multi-MeV photons are produced by electrons accelerated close to the limit of diffusive shock acceleration. Simultaneous GLAST and X-ray observations of high X-ray states will address the issue of the convex curvature in the future.

31 CFR 562.304 - Interest.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Interest. 562.304 Section 562.304... Definitions § 562.304 Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct...

31 CFR 589.304 - Interest.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Interest. 589.304 Section 589.304... § 589.304 Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct or...

31 CFR 588.304 - Interest.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Interest. 588.304 Section 588.304... § 588.304 Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct or...

31 CFR 562.304 - Interest.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Interest. 562.304 Section 562.304... Definitions § 562.304 Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct...

31 CFR 588.304 - Interest.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Interest. 588.304 Section 588.304... § 588.304 Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct or...

31 CFR 588.304 - Interest.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Interest. 588.304 Section 588.304... § 588.304 Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct or...

31 CFR 562.304 - Interest.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Interest. 562.304 Section 562.304... Definitions § 562.304 Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct...

31 CFR 562.304 - Interest.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Interest. 562.304 Section 562.304... Definitions § 562.304 Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct...

31 CFR 558.304 - Interest.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Interest. 558.304 Section 558.304....304 Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct or indirect. ...

31 CFR 588.304 - Interest.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Interest. 588.304 Section 588.304... § 588.304 Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct or...

48 CFR 806.304 - Approval of the justification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... justification. 806.304 Section 806.304 Federal Acquisition Regulations System DEPARTMENT OF VETERANS AFFAIRS COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 806.304....304(c), Table 806.304-1 provides the authorities who may approve a justification: Table 806.304.1...

5 CFR 304.108 - Compliance.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Compliance. 304.108 Section 304.108... APPOINTMENTS § 304.108 Compliance. (a) Each agency using 5 U.S.C. 3109 must establish and maintain a system of controls and oversight necessary to assure compliance with 5 U.S.C. 3109 and these regulations. The system...

5 CFR 304.108 - Compliance.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Compliance. 304.108 Section 304.108... APPOINTMENTS § 304.108 Compliance. (a) Each agency using 5 U.S.C. 3109 must establish and maintain a system of controls and oversight necessary to assure compliance with 5 U.S.C. 3109 and these regulations. The system...

Broadband Spectral Modeling of the Extreme Gigahertz-peaked Spectrum Radio Source PKS B0008-421

NASA Astrophysics Data System (ADS)

Callingham, J. R.; Gaensler, B. M.; Ekers, R. D.; Tingay, S. J.; Wayth, R. B.; Morgan, J.; Bernardi, G.; Bell, M. E.; Bhat, R.; Bowman, J. D.; Briggs, F.; Cappallo, R. J.; Deshpande, A. A.; Ewall-Wice, A.; Feng, L.; Greenhill, L. J.; Hazelton, B. J.; Hindson, L.; Hurley-Walker, N.; Jacobs, D. C.; Johnston-Hollitt, M.; Kaplan, D. L.; Kudrayvtseva, N.; Lenc, E.; Lonsdale, C. J.; McKinley, B.; McWhirter, S. R.; Mitchell, D. A.; Morales, M. F.; Morgan, E.; Oberoi, D.; Offringa, A. R.; Ord, S. M.; Pindor, B.; Prabu, T.; Procopio, P.; Riding, J.; Srivani, K. S.; Subrahmanyan, R.; Udaya Shankar, N.; Webster, R. L.; Williams, A.; Williams, C. L.

2015-08-01

We present broadband observations and spectral modeling of PKS B0008-421 and identify it as an extreme gigahertz-peaked spectrum (GPS) source. PKS B0008-421 is characterized by the steepest known spectral slope below the turnover, close to the theoretical limit of synchrotron self-absorption, and the smallest known spectral width of any GPS source. Spectral coverage of the source spans from 0.118 to 22 GHz, which includes data from the Murchison Widefield Array and the wide bandpass receivers on the Australia Telescope Compact Array. We have implemented a Bayesian inference model fitting routine to fit the data with internal free-free absorption (FFA), single- and double-component FFA in an external homogeneous medium, FFA in an external inhomogeneous medium, or single- and double-component synchrotron self-absorption models, all with and without a high-frequency exponential break. We find that without the inclusion of a high-frequency break these models cannot accurately fit the data, with significant deviations above and below the peak in the radio spectrum. The addition of a high-frequency break provides acceptable spectral fits for the inhomogeneous FFA and double-component synchrotron self-absorption models, with the inhomogeneous FFA model statistically favored. The requirement of a high-frequency spectral break implies that the source has ceased injecting fresh particles. Additional support for the inhomogeneous FFA model as being responsible for the turnover in the spectrum is given by the consistency between the physical parameters derived from the model fit and the implications of the exponential spectral break, such as the necessity of the source being surrounded by a dense ambient medium to maintain the peak frequency near the gigahertz region. This implies that PKS B0008-421 should display an internal H i column density greater than 1020 cm-2. The discovery of PKS B0008-421 suggests that the next generation of low radio frequency surveys could reveal a

A Single Sfp-Type Phosphopantetheinyl Transferase Plays a Major Role in the Biosynthesis of PKS and NRPS Derived Metabolites in Streptomyces ambofaciens ATCC23877

PubMed Central

Bunet, Robert; Riclea, Ramona; Laureti, Luisa; Hôtel, Laurence; Paris, Cédric; Girardet, Jean-Michel; Spiteller, Dieter; Dickschat, Jeroen S.; Leblond, Pierre; Aigle, Bertrand

2014-01-01

The phosphopantetheinyl transferases (PPTases) are responsible for the activation of the carrier protein domains of the polyketide synthases (PKS), non ribosomal peptide synthases (NRPS) and fatty acid synthases (FAS). The analysis of the Streptomyces ambofaciens ATCC23877 genome has revealed the presence of four putative PPTase encoding genes. One of these genes appears to be essential and is likely involved in fatty acid biosynthesis. Two other PPTase genes, samT0172 (alpN) and samL0372, are located within a type II PKS gene cluster responsible for the kinamycin production and an hybrid NRPS-PKS cluster involved in antimycin production, respectively, and their products were shown to be specifically involved in the biosynthesis of these secondary metabolites. Surprisingly, the fourth PPTase gene, which is not located within a secondary metabolite gene cluster, appears to play a pleiotropic role. Its product is likely involved in the activation of the acyl- and peptidyl-carrier protein domains within all the other PKS and NRPS complexes encoded by S. ambofaciens. Indeed, the deletion of this gene affects the production of the spiramycin and stambomycin macrolide antibiotics and of the grey spore pigment, all three being PKS-derived metabolites, as well as the production of the nonribosomally produced compounds, the hydroxamate siderophore coelichelin and the pyrrolamide antibiotic congocidine. In addition, this PPTase seems to act in concert with the product of samL0372 to activate the ACP and/or PCP domains of the antimycin biosynthesis cluster which is also responsible for the production of volatile lactones. PMID:24498152

5 CFR 179.304 - Notification procedures.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Notification procedures. 179.304 Section 179.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS CLAIMS COLLECTION STANDARDS Administrative Offset § 179.304 Notification procedures. Before collecting any debt...

48 CFR 304.7001 - Numbering acquisitions.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Numbering acquisitions. 304.7001 Section 304.7001 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATIVE MATTERS Acquisition Instrument Identification Numbering System 304.7001 Numbering acquisitions. (a...

41 CFR 51-9.304 - Fees.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 1 2010-07-01 2010-07-01 true Fees. 51-9.304 Section 51-9.304 Public Contracts and Property Management Other Provisions Relating to Public Contracts... Access to Records § 51-9.304 Fees. ...

48 CFR 370.304 - Contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Contract clauses. 370.304 Section 370.304 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES HHS SUPPLEMENTATIONS SPECIAL PROGRAMS AFFECTING ACQUISITION Acquisitions Involving Human Subjects 370.304 Contract clauses. (a...

40 CFR 304.42 - Miscellaneous provisions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 27 2010-07-01 2010-07-01 false Miscellaneous provisions. 304.42 Section 304.42 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY... CLAIMS Other Provisions § 304.42 Miscellaneous provisions. (a) Any party who proceeds with the...

48 CFR 37.304 - Contract clauses.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Contract clauses. 37.304 Section 37.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SPECIAL CATEGORIES OF CONTRACTING SERVICE CONTRACTING Dismantling, Demolition, or Removal of Improvements 37.304 Contract clauses...

29 CFR 1603.304 - Commission decision.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false Commission decision. 1603.304 Section 1603.304 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

29 CFR 1603.304 - Commission decision.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 29 Labor 4 2012-07-01 2012-07-01 false Commission decision. 1603.304 Section 1603.304 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

29 CFR 1603.304 - Commission decision.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 29 Labor 4 2013-07-01 2013-07-01 false Commission decision. 1603.304 Section 1603.304 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

29 CFR 1603.304 - Commission decision.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 29 Labor 4 2014-07-01 2014-07-01 false Commission decision. 1603.304 Section 1603.304 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

29 CFR 1603.304 - Commission decision.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 4 2011-07-01 2011-07-01 false Commission decision. 1603.304 Section 1603.304 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION PROCEDURES FOR PREVIOUSLY EXEMPT STATE AND LOCAL GOVERNMENT EMPLOYEE COMPLAINTS OF EMPLOYMENT DISCRIMINATION UNDER SECTION 304 OF...

7 CFR 765.304 - Unapproved disposition.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 7 2010-01-01 2010-01-01 false Unapproved disposition. 765.304 Section 765.304 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN SERVICING-REGULAR Disposal of Chattel Security § 765.304 Unapproved...

7 CFR 765.304 - Unapproved disposition.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 7 2011-01-01 2011-01-01 false Unapproved disposition. 765.304 Section 765.304 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN SERVICING-REGULAR Disposal of Chattel Security § 765.304 Unapproved...

7 CFR 1416.304 - Payment calculations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Payment calculations. 1416.304 Section 1416.304 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT... PROGRAMS Citrus Disaster Program § 1416.304 Payment calculations. (a) Payments will be calculated by...

49 CFR 172.304 - Marking requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 2 2011-10-01 2011-10-01 false Marking requirements. 172.304 Section 172.304 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY... SECURITY PLANS Marking § 172.304 Marking requirements. (a) The marking required in this subpart— (1) Must...

48 CFR 26.304 - Solicitation provision.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Solicitation provision. 26.304 Section 26.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC... Institutions 26.304 Solicitation provision. Insert the provision at 52.226-2, Historically Black College or...

13 CFR 304.4 - Performance evaluations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Performance evaluations. 304.4 Section 304.4 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF COMMERCE ECONOMIC DEVELOPMENT DISTRICTS § 304.4 Performance evaluations. (a) EDA shall evaluate the management...

Long-term Study of the Light Curve of PKS 1510-089 in GeV Energies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Prince, Raj; Gupta, Nayantara; Majumdar, Pratik, E-mail: rajprince@rri.res.in

2017-07-20

We have analyzed data from the flat-spectrum radio quasar PKS 1510-089 collected over a period of eight years from 2008 August to 2016 December with the Fermi -LAT. We have identified several flares of this highly variable source, studied their temporal and spectral properties in detail, and compared with previous works on flares of PKS 1510-089. Five major flares and a few subflares or substructures have been identified in our study. The fastest variability time is found to be 1.30 ± 0.18 hr between MJD 55852.063 and 55852.188, where we estimate the minimum size of the emission region to bemore » 4.85 × 10{sup 15} cm. In most of the flares, the spectral energy distributions are better fitted with a log-parabolic distribution compared to a simple power law or a power law with exponential cutoffs. This has strong physics implications regarding the nature of the high-energy gamma-ray emission region.« less

49 CFR 195.304 - Test pressure.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 49 Transportation 3 2012-10-01 2012-10-01 false Test pressure. 195.304 Section 195.304... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Pressure Testing § 195.304 Test pressure. The test pressure for each pressure test conducted under...

49 CFR 195.304 - Test pressure.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 49 Transportation 3 2010-10-01 2010-10-01 false Test pressure. 195.304 Section 195.304... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Pressure Testing § 195.304 Test pressure. The test pressure for each pressure test conducted under...

49 CFR 195.304 - Test pressure.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 49 Transportation 3 2011-10-01 2011-10-01 false Test pressure. 195.304 Section 195.304... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Pressure Testing § 195.304 Test pressure. The test pressure for each pressure test conducted under...

49 CFR 195.304 - Test pressure.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 49 Transportation 3 2014-10-01 2014-10-01 false Test pressure. 195.304 Section 195.304... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) PIPELINE SAFETY TRANSPORTATION OF HAZARDOUS LIQUIDS BY PIPELINE Pressure Testing § 195.304 Test pressure. The test pressure for each pressure test conducted under...

48 CFR 11.304 - Contract clause.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Contract clause. 11.304 Section 11.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING DESCRIBING AGENCY NEEDS Acceptable Material 11.304 Contract clause. Insert the clause at 52.211-5, Material...

45 CFR 304.12 - Incentive payments.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false Incentive payments. 304.12 Section 304.12 Public Welfare Regulations Relating to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT (CHILD SUPPORT... FEDERAL FINANCIAL PARTICIPATION § 304.12 Incentive payments. (a) Definitions. For the purposes of this...

16 CFR 304.2 - General requirement.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false General requirement. 304.2 Section 304.2 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS RULES AND REGULATIONS UNDER THE HOBBY PROTECTION ACT § 304.2 General requirement. Imitation political or numismatic...

24 CFR 1003.304 - Funding process.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 24 Housing and Urban Development 4 2012-04-01 2012-04-01 false Funding process. 1003.304 Section 1003.304 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED... Application and Selection Process § 1003.304 Funding process. (a) Notification. Area ONAPs will notify...

24 CFR 1003.304 - Funding process.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 4 2011-04-01 2011-04-01 false Funding process. 1003.304 Section 1003.304 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED... Application and Selection Process § 1003.304 Funding process. (a) Notification. Area ONAPs will notify...

24 CFR 1003.304 - Funding process.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 24 Housing and Urban Development 4 2014-04-01 2014-04-01 false Funding process. 1003.304 Section 1003.304 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED... Application and Selection Process § 1003.304 Funding process. (a) Notification. Area ONAPs will notify...

24 CFR 1003.304 - Funding process.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 24 Housing and Urban Development 4 2013-04-01 2013-04-01 false Funding process. 1003.304 Section 1003.304 Housing and Urban Development REGULATIONS RELATING TO HOUSING AND URBAN DEVELOPMENT (CONTINUED... Application and Selection Process § 1003.304 Funding process. (a) Notification. Area ONAPs will notify...

24 CFR 1003.304 - Funding process.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Funding process. 1003.304 Section 1003.304 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... Application and Selection Process § 1003.304 Funding process. (a) Notification. Area ONAPs will notify...

Swift detection of an X-ray flare from the flaring blazar PKS 0502+049

NASA Astrophysics Data System (ADS)

Ojha, Roopesh; Dutka, Michael

2013-03-01

Following the recent gamma-ray flaring activity of the flat spectrum radio quasar PKS 0502+049 (also known as 2FGL J0505.5+0501, Nolan et al. 2012, ApJS, 199, 31), detected by Fermi LAT on 2013 March 2 (ATel#4858), a Swift target of opportunity observation was performed on March 13.

47 CFR 65.304 - Capital structure.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 3 2010-10-01 2010-10-01 false Capital structure. 65.304 Section 65.304... OF RETURN PRESCRIPTION PROCEDURES AND METHODOLOGIES Exchange Carriers § 65.304 Capital structure. The proportion of each cost of capital component in the capital structure is equal to: Proportion in the capital...

16 CFR 304.1 - Terms defined.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Terms defined. 304.1 Section 304.1 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS RULES AND REGULATIONS UNDER THE HOBBY PROTECTION ACT § 304.1 Terms defined. (a) Act means the Hobby Protection Act...

Fermi LAT detection of renewed GeV gamma-ray activity from the gravitationally lensed blazar PKS 1830-211

NASA Astrophysics Data System (ADS)

Ciprini, Stefano

2012-06-01

The Large Area Telescope (LAT), one of the two instruments on the Fermi Gamma-ray Space Telescope, has observed increasing gamma-ray flux from a source positionally consistent with PKS 1830-211 (also known as 2FGL J1833.6-2104, Nolan et al. 2012, ApJS, 199, 31, placed at RA: 18h 33m 39.9s, Dec -21d 03m 40s, J2000, van Ommen et al., 1995, ApJ, 444, 561). PKS 1830-211 (z=2.507, Lovell et al. 1998, ApJ, 508, L51) is a distant and peculiar flat spectrum radio quasar with intervening absorption systems and being subject to gravitational lensing by a galaxy placed at z=0.886 (Wiklind & Combes 1996, Nature, 379, 11).

34 CFR 685.304 - Counseling borrowers.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 34 Education 4 2013-07-01 2013-07-01 false Counseling borrowers. 685.304 Section 685.304 Education... Payments for Direct Loan Program Schools § 685.304 Counseling borrowers. (a) Entrance counseling. (1) Except as provided in paragraph (a)(8) of this section, a school must ensure that entrance counseling is...

34 CFR 685.304 - Counseling borrowers.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 3 2010-07-01 2010-07-01 false Counseling borrowers. 685.304 Section 685.304 Education... Direct Loan Program Schools § 685.304 Counseling borrowers. (a) Entrance counseling. (1) Except as provided in paragraph (a)(8) of this section, a school must ensure that entrance counseling is conducted...

34 CFR 685.304 - Counseling borrowers.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 4 2011-07-01 2011-07-01 false Counseling borrowers. 685.304 Section 685.304 Education... Payments for Direct Loan Program Schools § 685.304 Counseling borrowers. (a) Entrance counseling. (1) Except as provided in paragraph (a)(8) of this section, a school must ensure that entrance counseling is...

34 CFR 685.304 - Counseling borrowers.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 34 Education 4 2012-07-01 2012-07-01 false Counseling borrowers. 685.304 Section 685.304 Education... Payments for Direct Loan Program Schools § 685.304 Counseling borrowers. (a) Entrance counseling. (1) Except as provided in paragraph (a)(8) of this section, a school must ensure that entrance counseling is...

34 CFR 685.304 - Counseling borrowers.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 34 Education 4 2014-07-01 2014-07-01 false Counseling borrowers. 685.304 Section 685.304 Education... Payments for Direct Loan Program Schools § 685.304 Counseling borrowers. (a) Entrance counseling. (1) Except as provided in paragraph (a)(8) of this section, a school must ensure that entrance counseling is...

1 CFR 304.7 - Business information.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 1 General Provisions 1 2012-01-01 2012-01-01 false Business information. 304.7 Section 304.7... Procedures for Disclosure of Records Under the Freedom of Information Act § 304.7 Business information. (a) In general. Business information obtained by the agency will be disclosed under the FOIA only under...

1 CFR 304.7 - Business information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 1 General Provisions 1 2013-01-01 2012-01-01 true Business information. 304.7 Section 304.7... Procedures for Disclosure of Records Under the Freedom of Information Act § 304.7 Business information. (a) In general. Business information obtained by the agency will be disclosed under the FOIA only under...

1 CFR 304.7 - Business information.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 1 General Provisions 1 2014-01-01 2012-01-01 true Business information. 304.7 Section 304.7... Procedures for Disclosure of Records Under the Freedom of Information Act § 304.7 Business information. (a) In general. Business information obtained by the agency will be disclosed under the FOIA only under...

22 CFR 304.1 - Scope; definitions.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Scope; definitions. 304.1 Section 304.1 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT General Provisions § 304.1 Scope; definitions. (a) This subpart applies to claims asserted under the Federal Tort Claims Act, as...

22 CFR 304.1 - Scope; definitions.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Scope; definitions. 304.1 Section 304.1 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT General Provisions § 304.1 Scope; definitions. (a) This subpart applies to claims asserted under the Federal Tort Claims Act, as...

48 CFR 3027.304-1 - General.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 7 2013-10-01 2012-10-01 true General. 3027.304-1 Section 3027.304-1 Federal Acquisition Regulations System DEPARTMENT OF HOMELAND SECURITY, HOMELAND SECURITY... subcontracts for experimental, developmental, or research work (FAR) 48 CFR 27.304-1(e)(2)(ii) may be submitted...

24 CFR 291.304 - Bidding process.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 24 Housing and Urban Development 2 2011-04-01 2011-04-01 false Bidding process. 291.304 Section 291.304 Housing and Urban Development Regulations Relating to Housing and Urban Development (Continued... Family Mortgage Loans § 291.304 Bidding process. (a) Submission of bids. All bids must be submitted to...

1 CFR 304.1 - General provisions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 1 General Provisions 1 2013-01-01 2012-01-01 true General provisions. 304.1 Section 304.1 General Provisions ADMINISTRATIVE CONFERENCE OF THE UNITED STATES DISCLOSURE OF RECORDS OR INFORMATION Procedures for Disclosure of Records Under the Freedom of Information Act § 304.1 General provisions. (a) This subpart...

1 CFR 304.1 - General provisions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 1 General Provisions 1 2012-01-01 2012-01-01 false General provisions. 304.1 Section 304.1 General Provisions ADMINISTRATIVE CONFERENCE OF THE UNITED STATES DISCLOSURE OF RECORDS OR INFORMATION Procedures for Disclosure of Records Under the Freedom of Information Act § 304.1 General provisions. (a) This subpart...

1 CFR 304.1 - General provisions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 1 General Provisions 1 2014-01-01 2012-01-01 true General provisions. 304.1 Section 304.1 General Provisions ADMINISTRATIVE CONFERENCE OF THE UNITED STATES DISCLOSURE OF RECORDS OR INFORMATION Procedures for Disclosure of Records Under the Freedom of Information Act § 304.1 General provisions. (a) This subpart...

10 CFR 205.304 - Other information.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 10 Energy 3 2013-01-01 2013-01-01 false Other information. 205.304 Section 205.304 Energy... to A Foreign Country § 205.304 Other information. Where the application is for authority to export less than 1,000,000 kilowatt hours annually, applicants need not furnish the information called for in...

20 CFR 801.304 - Business hours.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 20 Employees' Benefits 3 2011-04-01 2011-04-01 false Business hours. 801.304 Section 801.304 Employees' Benefits BENEFITS REVIEW BOARD, DEPARTMENT OF LABOR ESTABLISHMENT AND OPERATION OF THE BOARD Action by the Board § 801.304 Business hours. The office of the Clerk of the Board at Washington, DC...

20 CFR 801.304 - Business hours.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 20 Employees' Benefits 4 2012-04-01 2012-04-01 false Business hours. 801.304 Section 801.304 Employees' Benefits BENEFITS REVIEW BOARD, DEPARTMENT OF LABOR ESTABLISHMENT AND OPERATION OF THE BOARD Action by the Board § 801.304 Business hours. The office of the Clerk of the Board at Washington, DC...

20 CFR 801.304 - Business hours.

Code of Federal Regulations, 2013 CFR

2013-04-01

... 20 Employees' Benefits 4 2013-04-01 2013-04-01 false Business hours. 801.304 Section 801.304 Employees' Benefits BENEFITS REVIEW BOARD, DEPARTMENT OF LABOR ESTABLISHMENT AND OPERATION OF THE BOARD Action by the Board § 801.304 Business hours. The office of the Clerk of the Board at Washington, DC...

20 CFR 801.304 - Business hours.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 20 Employees' Benefits 4 2014-04-01 2014-04-01 false Business hours. 801.304 Section 801.304 Employees' Benefits BENEFITS REVIEW BOARD, DEPARTMENT OF LABOR ESTABLISHMENT AND OPERATION OF THE BOARD Action by the Board § 801.304 Business hours. The office of the Clerk of the Board at Washington, DC...

22 CFR 304.6 - Claims investigation.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Claims investigation. 304.6 Section 304.6 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.6 Claims investigation. (a) When a claim has been filed with the Peace Corps, the General Counsel will send...

22 CFR 304.6 - Claims investigation.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Claims investigation. 304.6 Section 304.6 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.6 Claims investigation. (a) When a claim has been filed with the Peace Corps, the General Counsel will send...

20 CFR 801.304 - Business hours.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Business hours. 801.304 Section 801.304 Employees' Benefits BENEFITS REVIEW BOARD, DEPARTMENT OF LABOR ESTABLISHMENT AND OPERATION OF THE BOARD Action by the Board § 801.304 Business hours. The office of the Clerk of the Board at Washington, DC...

49 CFR 195.304 - Test pressure.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 49 Transportation 3 2013-10-01 2013-10-01 false Test pressure. 195.304 Section 195.304... PIPELINE Pressure Testing § 195.304 Test pressure. The test pressure for each pressure test conducted under... case of a pipeline that is not visually inspected for leakage during the test, for at least an...

29 CFR 16.304 - Further proceedings.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 29 Labor 1 2011-07-01 2011-07-01 false Further proceedings. 16.304 Section 16.304 Labor Office of the Secretary of Labor EQUAL ACCESS TO JUSTICE ACT Procedures for Considering Applications § 16.304 Further proceedings. (a) Ordinarily, the determination of an award will be made on the basis of the...

5 CFR 847.304 - Time limit.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Time limit. 847.304 Section 847.304... Procedures for Elections Under the Retroactive Provisions § 847.304 Time limit. (a) Except as provided in paragraph (b) of this section, the time limit for making an election under subpart D of this part is August...

5 CFR 847.304 - Time limit.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 2 2013-01-01 2013-01-01 false Time limit. 847.304 Section 847.304... Procedures for Elections Under the Retroactive Provisions § 847.304 Time limit. (a) Except as provided in paragraph (b) of this section, the time limit for making an election under subpart D of this part is August...

5 CFR 847.304 - Time limit.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 2 2014-01-01 2014-01-01 false Time limit. 847.304 Section 847.304... Procedures for Elections Under the Retroactive Provisions § 847.304 Time limit. (a) Except as provided in paragraph (b) of this section, the time limit for making an election under subpart D of this part is August...

45 CFR 304.12 - Incentive payments.

Code of Federal Regulations, 2010 CFR

2010-10-01

... paid to the Federal government to reimburse its share of assistance payments under §§ 302.51 and 302.52... 45 Public Welfare 2 2010-10-01 2010-10-01 false Incentive payments. 304.12 Section 304.12 Public... FEDERAL FINANCIAL PARTICIPATION § 304.12 Incentive payments. (a) Definitions. For the purposes of this...

Metagenomic Analysis of Upwelling-Affected Brazilian Coastal Seawater Reveals Sequence Domains of Type I PKS and Modular NRPS

PubMed Central

Cuadrat, Rafael R. C.; Cury, Juliano C.; Dávila, Alberto M. R.

2015-01-01

Marine environments harbor a wide range of microorganisms from the three domains of life. These microorganisms have great potential to enable discovery of new enzymes and bioactive compounds for industrial use. However, only ~1% of microorganisms from the environment can currently be identified through cultured isolates, limiting the discovery of new compounds. To overcome this limitation, a metagenomics approach has been widely adopted for biodiversity studies on samples from marine environments. In this study, we screened metagenomes in order to estimate the potential for new natural compound synthesis mediated by diversity in the Polyketide Synthase (PKS) and Nonribosomal Peptide Synthetase (NRPS) genes. The samples were collected from the Praia dos Anjos (Angel’s Beach) surface water—Arraial do Cabo (Rio de Janeiro state, Brazil), an environment affected by upwelling. In order to evaluate the potential for screening natural products in Arraial do Cabo samples, we used KS (keto-synthase) and C (condensation) domains (from PKS and NRPS, respectively) to build Hidden Markov Models (HMM) models. From both samples, a total of 84 KS and 46 C novel domain sequences were obtained, showing the potential of this environment for the discovery of new genes of biotechnological interest. These domains were classified by phylogenetic analysis and this was the first study conducted to screen PKS and NRPS genes in an upwelling affected sample PMID:26633360

Effects of disrupting the polyketide synthase gene WdPKS1 in Wangiella [Exophiala] dermatitidis on melanin production and resistance to killing by antifungal compounds, enzymatic degradation, and extremes in temperature

PubMed Central

Paolo, William F; Dadachova, Ekaterina; Mandal, Piyali; Casadevall, Arturo; Szaniszlo, Paul J; Nosanchuk, Joshua D

2006-01-01

Background Wangiella dermatitidis is a human pathogenic fungus that is an etiologic agent of phaeohyphomycosis. W. dermatitidis produces a black pigment that has been identified as a dihydroxynaphthalene melanin and the production of this pigment is associated with its virulence. Cell wall pigmentation in W. dermatitidis depends on the WdPKS1 gene, which encodes a polyketide synthase required for generating the key precursor for dihydroxynaphthalene melanin biosynthesis. Results We analyzed the effects of disrupting WdPKS1 on dihydroxynaphthalene melanin production and resistance to antifungal compounds. Transmission electron microscopy revealed that wdpks1Δ-1 yeast had thinner cell walls that lacked an electron-opaque layer compared to wild-type cells. However, digestion of the wdpks1Δ-1 yeast revealed small black particles that were consistent with a melanin-like compound, because they were acid-resistant, reacted with melanin-binding antibody, and demonstrated a free radical signature by electron spin resonance analysis. Despite lacking the WdPKS1 gene, the mutant yeast were capable of catalyzing the formation of melanin from L-3,4-dihyroxyphenylalanine. The wdpks1Δ-1 cells were significantly more susceptible to killing by voriconazole, amphotericin B, NP-1 [a microbicidal peptide], heat and cold, and lysing enzymes than the heavily melanized parental or complemented strains. Conclusion In summary, W. dermatitidis makes WdPKS-dependent and -independent melanins, and the WdPKS1-dependent deposition of melanin in the cell wall confers protection against antifungal agents and environmental stresses. The biological role of the WdPKS-independent melanin remains unclear. PMID:16784529

Time delay in the Einstein ring PKS 1830-211

NASA Technical Reports Server (NTRS)

Van Ommen, T. D.; Jones, D. L.; Preston, R. A.; Jauncey, D. L.

1995-01-01

We present radio observations of the gravitational lens PKS 1830-211 at 8.4 and 15 GHz acquired using the Very Large Array. The observations were made over a 13 month period. Significant flux density changes over this period provide strong constraints on the time delay between the two lensed images and suffest a value of 44 +/- 9 days. This offers new direct evidence that this source is indeed a gravitational lens. The lens distance is dependent upon the model chosen, but reasonable limits on the mass of the lensing galaxy suggest that it is unlikely to be at a redshift less than a few tenths, and may well be significantly more distant.

48 CFR 1306.304 - Approval of the justification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... justification. 1306.304 Section 1306.304 Federal Acquisition Regulations System DEPARTMENT OF COMMERCE COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 1306.304... open competition at the dollar thresholds in FAR 6.304 is set forth in CAM 1301.70. ...

Sharp increase of radio flux in flaring blazar PKS 1424-41

NASA Astrophysics Data System (ADS)

Nemenashi, Pfesesani; Gaylard, Michael; Ojha, Roopesh

2013-02-01

The Hartebeesthoek Radio Astronomy Observatory (HartRAO) 26m telescope has detected a sharp increase in the flux density of PKS 1424-41 (also known as 2FGL J1428.0-4206, Nolan et al. 2012, ApJS, 199, 31) coinciding with the flaring activity reported at gamma-ray and optical (ATel#4714), X-ray (ATel#4717, ATel#4770) and OIR (ATel#4775) bands. At 8.4 GHz, its flux has risen from 6.1 Jy on 2013 Jan 08 to 7.0 Jy on 2013 Jan 28 and it remains at that level.

40 CFR 304.23 - Disclosure and challenge procedures.

Code of Federal Regulations, 2010 CFR

2010-07-01

.... 304.23 Section 304.23 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND... RECOVERY CLAIMS Jurisdiction of Arbitrator, Referral of Claims, and Appointment of Arbitrator § 304.23 Disclosure and challenge procedures. (a) A person appointed as an Arbitrator under § 304.22 of this part...

48 CFR 570.304 - General source selection procedures.

Code of Federal Regulations, 2011 CFR

2011-10-01

... procedures. 570.304 Section 570.304 Federal Acquisition Regulations System GENERAL SERVICES ADMINISTRATION... Leasehold Interests in Real Property Over the Simplified Lease Acquisition Threshold 570.304 General source... disadvantaged business concerns in performance of the contract, and other factors as required by FAR 15.304 as...

48 CFR 2806.304 - Approval of the justification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... justification. 2806.304 Section 2806.304 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE Competition and Acquisition Planning COMPETITION REQUIREMENTS Other Than Full and Open Competition 2806.304...) Pursuant to FAR 6.304(c), a class justification for other than full and open competition shall be approved...

7 CFR 1437.304 - Floriculture.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Floriculture. 1437.304 Section 1437.304 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS NONINSURED CROP DISASTER ASSISTANCE PROGRAM Determining...

7 CFR 1437.304 - Floriculture.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 10 2014-01-01 2014-01-01 false Floriculture. 1437.304 Section 1437.304 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS NONINSURED CROP DISASTER ASSISTANCE PROGRAM Determining...

7 CFR 1437.304 - Floriculture.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Floriculture. 1437.304 Section 1437.304 Agriculture Regulations of the Department of Agriculture (Continued) COMMODITY CREDIT CORPORATION, DEPARTMENT OF AGRICULTURE LOANS, PURCHASES, AND OTHER OPERATIONS NONINSURED CROP DISASTER ASSISTANCE PROGRAM Determining...

5 CFR 9701.304 - Definitions.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Definitions. 9701.304 Section 9701.304 Administrative Personnel DEPARTMENT OF HOMELAND SECURITY HUMAN RESOURCES MANAGEMENT SYSTEM (DEPARTMENT OF HOMELAND SECURITY-OFFICE OF PERSONNEL MANAGEMENT) DEPARTMENT OF HOMELAND SECURITY HUMAN RESOURCES...

5 CFR 582.304 - Nonliability for disclosure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Nonliability for disclosure. 582.304 Section 582.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS COMMERCIAL GARNISHMENT OF FEDERAL EMPLOYEES' PAY Compliance With Legal Process § 582.304 Nonliability for...

5 CFR 582.304 - Nonliability for disclosure.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Nonliability for disclosure. 582.304 Section 582.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS COMMERCIAL GARNISHMENT OF FEDERAL EMPLOYEES' PAY Compliance With Legal Process § 582.304 Nonliability for...

5 CFR 582.304 - Nonliability for disclosure.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Nonliability for disclosure. 582.304 Section 582.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS COMMERCIAL GARNISHMENT OF FEDERAL EMPLOYEES' PAY Compliance With Legal Process § 582.304 Nonliability for...

5 CFR 582.304 - Nonliability for disclosure.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Nonliability for disclosure. 582.304 Section 582.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS COMMERCIAL GARNISHMENT OF FEDERAL EMPLOYEES' PAY Compliance With Legal Process § 582.304 Nonliability for...

5 CFR 582.304 - Nonliability for disclosure.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Nonliability for disclosure. 582.304 Section 582.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS COMMERCIAL GARNISHMENT OF FEDERAL EMPLOYEES' PAY Compliance With Legal Process § 582.304 Nonliability for...

28 CFR 301.304 - Representation of claimant.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Representation of claimant. 301.304 Section 301.304 Judicial Administration FEDERAL PRISON INDUSTRIES, INC., DEPARTMENT OF JUSTICE INMATE ACCIDENT COMPENSATION Compensation for Work-Related Physical Impairment or Death § 301.304 Representation...

48 CFR 28.304 - Risk-pooling arrangements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Risk-pooling arrangements. 28.304 Section 28.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS BONDS AND INSURANCE Insurance 28.304 Risk-pooling arrangements. Agencies may...

40 CFR 304.20 - Jurisdiction of Arbitrator.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 27 2010-07-01 2010-07-01 false Jurisdiction of Arbitrator. 304.20 Section 304.20 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY... CLAIMS Jurisdiction of Arbitrator, Referral of Claims, and Appointment of Arbitrator § 304.20...

48 CFR 306.304 - Approval of the justification.

Code of Federal Regulations, 2011 CFR

2011-10-01

... justification. 306.304 Section 306.304 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 306.304... acquisitions in the dollar amount cited in FAR 6.304(a)(2) through (a)(4), the CCO, if applicable, and the HCA...

The ordinary life of the γ-ray emitting narrow-line Seyfert 1 galaxy PKS 1502+036

DOE PAGES

D'Ammando, F.; Orienti, M.; Doi, A.; ...

2013-06-03

In this paper, we report on multifrequency observations of the γ-ray emitting narrow-line Seyfert 1 galaxy PKS 1502+036 performed from radio to γ-rays during 2008 August–2012 November by Fermi-Large Area Telescope (LAT), Swift (X-ray Telescope and Ultraviolet/Optical Telescope), Owens Valley Radio Observatory, Very Long Baseline Array (VLBA) and Very Large Array. No significant variability has been observed in γ-rays, with 0.1–100 GeV flux that ranged between (3–7) × 10 –8 ph cm –2 s –1 using 3-month time bins. The photon index of the LAT spectrum (Γ = 2.60 ± 0.06) and the apparent isotropic γ-ray luminosity (L0.1-100 GeV =more » 7.8 × 10 45 erg s –1) over 51 months are typical of a flat spectrum radio quasar. The radio spectral variability and the one-sided structure, in addition to the observed γ-ray luminosity, suggest a relativistic jet with a high Doppler factor. In contrast to SBS 0846+513, the VLBA at 15 GHz did not observe superluminal motion for PKS 1502+036. Despite having the optical characteristics typical of a narrow-line Seyfert 1 galaxy, radio and γ-ray properties of PKS 1502+036 are found to be similar to those of a blazar at the low end of the black hole mass distribution for blazars. As a result, this is in agreement with what has been found in the case of the other γ-ray emitting narrow-line Seyfert 1 SBS 0846+513.« less

48 CFR 9901.304 - Membership.

Code of Federal Regulations, 2010 CFR

2010-10-01

... Administrator. (d) An individual who is particularly knowledgeable about cost accounting problems and systems... Section 9901.304 Federal Acquisition Regulations System COST ACCOUNTING STANDARDS BOARD, OFFICE OF FEDERAL PROCUREMENT POLICY, OFFICE OF MANAGEMENT AND BUDGET ADMINISTRATION RULES AND PROCEDURES 9901.304 Membership...

5 CFR 581.304 - Nonliability for disclosure.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 1 2012-01-01 2012-01-01 false Nonliability for disclosure. 581.304 Section 581.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROCESSING GARNISHMENT ORDERS FOR CHILD SUPPORT AND/OR ALIMONY Compliance With Process § 581.304 Nonliability...

5 CFR 581.304 - Nonliability for disclosure.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Nonliability for disclosure. 581.304 Section 581.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROCESSING GARNISHMENT ORDERS FOR CHILD SUPPORT AND/OR ALIMONY Compliance With Process § 581.304 Nonliability...

5 CFR 581.304 - Nonliability for disclosure.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Nonliability for disclosure. 581.304 Section 581.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROCESSING GARNISHMENT ORDERS FOR CHILD SUPPORT AND/OR ALIMONY Compliance With Process § 581.304 Nonliability...

5 CFR 581.304 - Nonliability for disclosure.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Nonliability for disclosure. 581.304 Section 581.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROCESSING GARNISHMENT ORDERS FOR CHILD SUPPORT AND/OR ALIMONY Compliance With Process § 581.304 Nonliability...

5 CFR 581.304 - Nonliability for disclosure.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Nonliability for disclosure. 581.304 Section 581.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PROCESSING GARNISHMENT ORDERS FOR CHILD SUPPORT AND/OR ALIMONY Compliance With Process § 581.304 Nonliability...

12 CFR 1102.304 - Federal Register publication.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 12 Banks and Banking 7 2010-01-01 2010-01-01 false Federal Register publication. 1102.304 Section 1102.304 Banks and Banking FEDERAL FINANCIAL INSTITUTIONS EXAMINATION COUNCIL APPRAISER REGULATION Description of Office, Procedures, Public Information § 1102.304 Federal Register publication. The ASC...

40 CFR 304.25 - Ex parte communication.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 27 2010-07-01 2010-07-01 false Ex parte communication. 304.25 Section 304.25 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY... CLAIMS Jurisdiction of Arbitrator, Referral of Claims, and Appointment of Arbitrator § 304.25 Ex parte...

48 CFR 304.7000 - Scope of subpart.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Scope of subpart. 304.7000 Section 304.7000 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATIVE MATTERS Acquisition Instrument Identification Numbering System 304.7000 Scope of subpart. This subpart...

40 CFR 304.11 - Scope and applicability.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 27 2010-07-01 2010-07-01 false Scope and applicability. 304.11 Section 304.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY... CLAIMS General § 304.11 Scope and applicability. The procedures established by this regulation govern the...

45 CFR 304.10 - General administrative requirements.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false General administrative requirements. 304.10 Section 304.10 Public Welfare Regulations Relating to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT... HUMAN SERVICES FEDERAL FINANCIAL PARTICIPATION § 304.10 General administrative requirements. As a...

10 CFR 600.304 - Special award conditions.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Special award conditions. 600.304 Section 600.304 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES Administrative Requirements for Grants and Cooperative Agreements With For-Profit Organizations General § 600.304 Special...

12 CFR 1102.304 - Federal Register publication.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 12 Banks and Banking 9 2013-01-01 2013-01-01 false Federal Register publication. 1102.304 Section 1102.304 Banks and Banking FEDERAL FINANCIAL INSTITUTIONS EXAMINATION COUNCIL APPRAISER REGULATION Description of Office, Procedures, Public Information § 1102.304 Federal Register publication. The ASC...

5 CFR 410.304 - Funding training programs.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false Funding training programs. 410.304 Section 410.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS TRAINING Establishing and Implementing Training Programs § 410.304 Funding training programs. Section 4112 of title 5...

Diverse bacterial PKS sequences derived from okadaic acid-producing dinoflagellates.

PubMed

Perez, Roberto; Liu, Li; Lopez, Jose; An, Tianying; Rein, Kathleen S

2008-05-22

Okadaic acid (OA) and the related dinophysistoxins are isolated from dinoflagellates of the genus Prorocentrum and Dinophysis. Bacteria of the Roseobacter group have been associated with okadaic acid producing dinoflagellates and have been previously implicated in OA production. Analysis of 16S rRNA libraries reveals that Roseobacter are the most abundant bacteria associated with OA producing dinoflagellates of the genus Prorocentrum and are not found in association with non-toxic dinoflagellates. While some polyketide synthase (PKS) genes form a highly supported Prorocentrum clade, most appear to be bacterial, but unrelated to Roseobacter or Alpha-Proteobacterial PKSs or those derived from other Alveolates Karenia brevis or Crytosporidium parvum.

Diverse Bacterial PKS Sequences Derived From Okadaic Acid-Producing Dinoflagellates

PubMed Central

Perez, Roberto; Liu, Li; Lopez, Jose; An, Tianying; Rein, Kathleen S.

2008-01-01

Okadaic acid (OA) and the related dinophysistoxins are isolated from dinoflagellates of the genus Prorocentrum and Dinophysis. Bacteria of the Roseobacter group have been associated with okadaic acid producing dinoflagellates and have been previously implicated in OA production. Analysis of 16S rRNA libraries reveals that Roseobacter are the most abundant bacteria associated with OA producing dinoflagellates of the genus Prorocentrum and are not found in association with non-toxic dinoflagellates. While some polyketide synthase (PKS) genes form a highly supported Prorocentrum clade, most appear to be bacterial, but unrelated to Roseobacter or Alpha-Proteobacterial PKSs or those derived from other Alveolates Karenia brevis or Crytosporidium parvum. PMID:18728765

47 CFR 27.304-27.307 - [Reserved

Code of Federal Regulations, 2011 CFR

2011-10-01

... 47 Telecommunication 2 2011-10-01 2011-10-01 false [Reserved] 27.304-27.307 Section 27.304-27.307 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Application, Licensing, and Processing Rules for WCS §§ 27.304-27.307 [Reserved] ...

47 CFR 27.304-27.307 - [Reserved

Code of Federal Regulations, 2010 CFR

2010-10-01

... 47 Telecommunication 2 2010-10-01 2010-10-01 false [Reserved] 27.304-27.307 Section 27.304-27.307 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) COMMON CARRIER SERVICES MISCELLANEOUS WIRELESS COMMUNICATIONS SERVICES Application, Licensing, and Processing Rules for WCS §§ 27.304-27.307 [Reserved] ...

41 CFR 105-54.304 - Cost guidelines.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Cost guidelines. 105-54.304 Section 105-54.304 Public Contracts and Property Management Federal Property Management... Administration 54-ADVISORY COMMITTEE MANAGEMENT 54.3-Advisory Committee Procedures § 105-54.304 Cost guidelines...

5 CFR 362.304 - Movement between agencies.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 5 Administrative Personnel 1 2014-01-01 2014-01-01 false Movement between agencies. 362.304 Section 362.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PATHWAYS PROGRAMS Recent Graduates Program § 362.304 Movement between agencies. (a) A Recent Graduate may apply for...

5 CFR 362.304 - Movement between agencies.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 5 Administrative Personnel 1 2013-01-01 2013-01-01 false Movement between agencies. 362.304 Section 362.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PATHWAYS PROGRAMS Recent Graduates Program § 362.304 Movement between agencies. (a) A Recent Graduate may apply for...

40 CFR 304.31 - Pre-hearing conference.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 27 2010-07-01 2010-07-01 false Pre-hearing conference. 304.31 Section 304.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY... CLAIMS Hearings Before the Arbitrator § 304.31 Pre-hearing conference. (a) The Arbitrator and the parties...

34 CFR 304.1 - Purpose.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false Purpose. 304.1 Section 304.1 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION SERVICE OBLIGATIONS UNDER SPECIAL EDUCATION-PERSONNEL DEVELOPMENT TO...

34 CFR 304.1 - Purpose.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true Purpose. 304.1 Section 304.1 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION SERVICE OBLIGATIONS UNDER SPECIAL EDUCATION-PERSONNEL DEVELOPMENT TO...

48 CFR 44.304 - Surveillance.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Surveillance. 44.304... SUBCONTRACTING POLICIES AND PROCEDURES Contractors' Purchasing Systems Reviews 44.304 Surveillance. (a) The ACO shall maintain a sufficient level of surveillance to ensure that the contractor is effectively managing...

48 CFR 44.304 - Surveillance.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Surveillance. 44.304... SUBCONTRACTING POLICIES AND PROCEDURES Contractors' Purchasing Systems Reviews 44.304 Surveillance. (a) The ACO shall maintain a sufficient level of surveillance to ensure that the contractor is effectively managing...

48 CFR 44.304 - Surveillance.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Surveillance. 44.304... SUBCONTRACTING POLICIES AND PROCEDURES Contractors' Purchasing Systems Reviews 44.304 Surveillance. (a) The ACO shall maintain a sufficient level of surveillance to ensure that the contractor is effectively managing...

48 CFR 44.304 - Surveillance.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Surveillance. 44.304... SUBCONTRACTING POLICIES AND PROCEDURES Contractors' Purchasing Systems Reviews 44.304 Surveillance. (a) The ACO shall maintain a sufficient level of surveillance to ensure that the contractor is effectively managing...

48 CFR 44.304 - Surveillance.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Surveillance. 44.304... SUBCONTRACTING POLICIES AND PROCEDURES Contractors' Purchasing Systems Reviews 44.304 Surveillance. (a) The ACO shall maintain a sufficient level of surveillance to ensure that the contractor is effectively managing...

46 CFR 502.304 - Procedure and filing fee.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 9 2011-10-01 2011-10-01 false Procedure and filing fee. 502.304 Section 502.304... Informal Procedure for Adjudication of Small Claims § 502.304 Procedure and filing fee. (a) A sworn claim... recommence. [Rule 304.] [49 FR 44369, Nov. 6, 1984, as amended at 59 FR 59170, Nov. 16, 1994; 67 FR 39859...

High-energy properties of the high-redshift flat spectrum radio quasar PKS 2149-306

DOE PAGES

D'Ammando, F.; Orienti, M.

2015-11-19

We investigate the γ-ray and X-ray properties of the flat spectrum radio quasar PKS 2149-306 at redshift z = 2.345. A strong γ-ray flare from this source was detected by the Large Area Telescope on board the Fermi Gamma-ray Space Telescope satellite in 2013 January, reaching on January 20 a daily peak flux of (301 ± 36)×10 -8 ph cm -2 s -1 in the 0.1–100 GeV energy range. This flux corresponds to an apparent isotropic luminosity of (1.5±0.2)×1050 erg s -1, comparable to the highest values observed by a blazar so far. During the flare the increase of fluxmore » was accompanied by a significant change of the spectral properties. Moreover significant flux variations on a 6-h time- scale were observed, compatible with the light crossing time of the event horizon of the central black hole. The broad band X-ray spectra of PKS 2149-306 observed by Swift-XRT and NuSTAR are well described by a broken power-law model, with a very hard spectrum (Γ 1 ~1) below the break energy, at Ebreak = 2.5–3.0 keV, and Γ 2 ~ 1.4–1.5 above the break energy. The steepening of the spectrum below ~3 keV may indicate that the soft X- ray emission is produced by the low-energy relativistic electrons. This is in agreement with the small variability amplitude and the lack of spectral changes in that part of the X-ray spectrum observed between the two NuSTAR and Swift joint observations. As for the other high-redshift FSRQ detected by both Fermi-LAT and Swift-BAT, the photon index of PKS 2149-306 in hard X-ray is 1.6 or lower and the average γ-ray luminosity higher than 2×1048 erg s -1.« less

High-energy properties of the high-redshift flat spectrum radio quasar PKS 2149-306

NASA Astrophysics Data System (ADS)

D'Ammando, F.; Orienti, M.

2016-01-01

We investigate the γ-ray and X-ray properties of the flat spectrum radio quasar PKS 2149-306 at redshift z = 2.345. A strong γ-ray flare from this source was detected by the Large Area Telescope on board the Fermi Gamma-ray Space Telescope satellite in 2013 January, reaching on January 20 a daily peak flux of (301 ± 36) × 10-8 ph cm-2 s-1 in the 0.1-100 GeV energy range. This flux corresponds to an apparent isotropic luminosity of (1.5 ± 0.2) × 1050 erg s-1, comparable to the highest values observed by a blazar so far. During the flare the increase of flux was accompanied by a significant change of the spectral properties. Moreover significant flux variations on a 6-h time-scale were observed, compatible with the light crossing time of the event horizon of the central black hole. The broad-band X-ray spectra of PKS 2149-306 observed by Swift-XRT and NuSTAR are well described by a broken power-law model, with a very hard spectrum (Γ1 ˜ 1) below the break energy, at E break = 2.5-3.0 keV, and Γ2 ˜ 1.4-1.5 above the break energy. The steepening of the spectrum below ˜3 keV may indicate that the soft X-ray emission is produced by the low-energy relativistic electrons. This is in agreement with the small variability amplitude and the lack of spectral changes in that part of the X-ray spectrum observed between the two NuSTAR and Swift joint observations. As for the other high-redshift FSRQ detected by both Fermi-LAT and Swift-BAT, the photon index of PKS 2149-306 in hard X-ray is 1.6 or lower and the average γ-ray luminosity higher than 2 × 1048 erg s-1.

Investigation of Thermal Processing on the Properties of PS304: A Solid Lubricant Coating

NASA Technical Reports Server (NTRS)

Benoy, Patricia A.; Williams, Syreeta (Technical Monitor)

2002-01-01

The effect of thermal processing on PS304, a solid lubricant coating, was investigated. PS304 is a plasma sprayed solid lubricant consisting of 10% Ag and 10% BaF2 and CaF2 in a eutectic mixture for low and high temperature lubricity respectively. In addition, PS304 contains 20% Cr2O3 for increased hardness and 60% NiCr which acts as a binder. All percents are in terms of weight not volume. Previous research on thermal processing (NAG3-2245) of PS304 revealed that substrate affected both the pre- and post-anneal hardness of the plasma spray coating. The objective of this grant was to both quantify this effect and determine whether the root cause was an artifact of the substrate or an actual difference in hardness due to interaction between the substrate and the coating. In addition to clarifying past research developments new data was sought in terms of coating growth due to annealing.

10 CFR 590.304 - Protests and answers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 10 Energy 4 2010-01-01 2010-01-01 false Protests and answers. 590.304 Section 590.304 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) ADMINISTRATIVE PROCEDURES WITH RESPECT TO THE IMPORT AND EXPORT OF NATURAL GAS Procedures § 590.304 Protests and answers. (a) Any...

10 CFR 590.304 - Protests and answers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Protests and answers. 590.304 Section 590.304 Energy DEPARTMENT OF ENERGY (CONTINUED) NATURAL GAS (ECONOMIC REGULATORY ADMINISTRATION) ADMINISTRATIVE PROCEDURES WITH RESPECT TO THE IMPORT AND EXPORT OF NATURAL GAS Procedures § 590.304 Protests and answers. (a) Any...

7 CFR 868.304 - Broken kernels determination.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 7 2011-01-01 2011-01-01 false Broken kernels determination. 868.304 Section 868.304 Agriculture Regulations of the Department of Agriculture (Continued) GRAIN INSPECTION, PACKERS AND STOCKYARD... Application of Standards § 868.304 Broken kernels determination. Broken kernels shall be determined by the use...

5 CFR 2604.304 - Appeal of denials.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 3 2010-01-01 2010-01-01 false Appeal of denials. 2604.304 Section 2604.304 Administrative Personnel OFFICE OF GOVERNMENT ETHICS ORGANIZATION AND PROCEDURES FREEDOM OF... Production and Disclosure of Records Under FOIA § 2604.304 Appeal of denials. (a) Right of appeal. If a...

46 CFR 535.304 - Agency agreements-exemption.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 46 Shipping 9 2011-10-01 2011-10-01 false Agency agreements-exemption. 535.304 Section 535.304 Shipping FEDERAL MARITIME COMMISSION REGULATIONS AFFECTING OCEAN SHIPPING IN FOREIGN COMMERCE OCEAN COMMON CARRIER AND MARINE TERMINAL OPERATOR AGREEMENTS SUBJECT TO THE SHIPPING ACT OF 1984 Exemptions § 535.304...

50 CFR 222.304 - Renewal of permits.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 50 Wildlife and Fisheries 9 2011-10-01 2011-10-01 false Renewal of permits. 222.304 Section 222.304 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND ATMOSPHERIC... Permit Procedures § 222.304 Renewal of permits. When the permit is renewable and a permittee intends to...

10 CFR 1023.304 - Eligibility of applicants.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Eligibility of applicants. 1023.304 Section 1023.304 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) CONTRACT APPEALS Procedures Relating to Awards Under the Equal Access to Justice Act General Provisions § 1023.304 Eligibility of applicants. (a) To be eligible...

7 CFR 868.304 - Broken kernels determination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 7 2010-01-01 2010-01-01 false Broken kernels determination. 868.304 Section 868.304 Agriculture Regulations of the Department of Agriculture (Continued) GRAIN INSPECTION, PACKERS AND STOCKYARD... Application of Standards § 868.304 Broken kernels determination. Broken kernels shall be determined by the use...

40 CFR 304.24 - Intervention and withdrawal.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 40 Protection of Environment 27 2010-07-01 2010-07-01 false Intervention and withdrawal. 304.24 Section 304.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY... Intervention and withdrawal. (a)(1) No later than thirty days prior to the pre-hearing conference (see § 304.31...

40 CFR 304.24 - Intervention and withdrawal.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 40 Protection of Environment 28 2014-07-01 2014-07-01 false Intervention and withdrawal. 304.24 Section 304.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY... Intervention and withdrawal. (a)(1) No later than thirty days prior to the pre-hearing conference (see § 304.31...

40 CFR 304.24 - Intervention and withdrawal.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 29 2012-07-01 2012-07-01 false Intervention and withdrawal. 304.24 Section 304.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY... Intervention and withdrawal. (a)(1) No later than thirty days prior to the pre-hearing conference (see § 304.31...

40 CFR 304.24 - Intervention and withdrawal.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 28 2011-07-01 2011-07-01 false Intervention and withdrawal. 304.24 Section 304.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY... Intervention and withdrawal. (a)(1) No later than thirty days prior to the pre-hearing conference (see § 304.31...

40 CFR 304.24 - Intervention and withdrawal.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 29 2013-07-01 2013-07-01 false Intervention and withdrawal. 304.24 Section 304.24 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY... Intervention and withdrawal. (a)(1) No later than thirty days prior to the pre-hearing conference (see § 304.31...

31 CFR 543.304 - Entity.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Entity. 543.304 Section 543.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS... Entity. The term entity means a partnership, association, trust, joint venture, corporation, group...

31 CFR 543.304 - Entity.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Entity. 543.304 Section 543.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS... Entity. The term entity means a partnership, association, trust, joint venture, corporation, group...

31 CFR 510.304 - Interest.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Interest. 510.304 Section 510.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY NORTH KOREA SANCTIONS REGULATIONS General Definitions § 510...

31 CFR 510.304 - Interest.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Interest. 510.304 Section 510.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY NORTH KOREA SANCTIONS REGULATIONS General Definitions § 510...

31 CFR 510.304 - Interest.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Interest. 510.304 Section 510.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY NORTH KOREA SANCTIONS REGULATIONS General Definitions § 510...

31 CFR 593.304 - Interest.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Interest. 593.304 Section 593.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY FORMER LIBERIAN REGIME OF CHARLES TAYLOR SANCTIONS REGULATIONS...

31 CFR 593.304 - Interest.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Interest. 593.304 Section 593.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY FORMER LIBERIAN REGIME OF CHARLES TAYLOR SANCTIONS REGULATIONS...

31 CFR 593.304 - Interest.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Interest. 593.304 Section 593.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY FORMER LIBERIAN REGIME OF CHARLES TAYLOR SANCTIONS REGULATIONS...

31 CFR 593.304 - Interest.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Interest. 593.304 Section 593.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY FORMER LIBERIAN REGIME OF CHARLES TAYLOR SANCTIONS REGULATIONS...

31 CFR 593.304 - Interest.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Interest. 593.304 Section 593.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY FORMER LIBERIAN REGIME OF CHARLES TAYLOR SANCTIONS REGULATIONS...

31 CFR 510.304 - Interest.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Interest. 510.304 Section 510.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY NORTH KOREA SANCTIONS REGULATIONS General Definitions § 510...

31 CFR 547.304 - Entity.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Entity. 547.304 Section 547.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY DEMOCRATIC REPUBLIC OF THE CONGO SANCTIONS REGULATIONS General...

31 CFR 547.304 - Entity.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Entity. 547.304 Section 547.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY DEMOCRATIC REPUBLIC OF THE CONGO SANCTIONS REGULATIONS General...

31 CFR 547.304 - Entity.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Entity. 547.304 Section 547.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY DEMOCRATIC REPUBLIC OF THE CONGO SANCTIONS REGULATIONS General...

31 CFR 547.304 - Entity.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Entity. 547.304 Section 547.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY DEMOCRATIC REPUBLIC OF THE CONGO SANCTIONS REGULATIONS General...

31 CFR 547.304 - Entity.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Entity. 547.304 Section 547.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY DEMOCRATIC REPUBLIC OF THE CONGO SANCTIONS REGULATIONS General...

7 CFR 764.304 - Rates and terms.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 7 2010-01-01 2010-01-01 false Rates and terms. 764.304 Section 764.304 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN MAKING Youth Loan Program § 764.304 Rates and terms. (a) Rates. (1) The...

7 CFR 764.304 - Rates and terms.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 7 2011-01-01 2011-01-01 false Rates and terms. 764.304 Section 764.304 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE SPECIAL PROGRAMS DIRECT LOAN MAKING Youth Loan Program § 764.304 Rates and terms. (a) Rates. (1) The...

22 CFR 304.8 - Limitations on authority.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Limitations on authority. 304.8 Section 304.8 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.8 Limitations on authority. (a) An award, compromise, or settlement of a claim under section 2672 of title 28...

22 CFR 304.8 - Limitations on authority.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Limitations on authority. 304.8 Section 304.8 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.8 Limitations on authority. (a) An award, compromise, or settlement of a claim under section 2672 of title 28...

25 CFR 304.6 - Responsibility of dealer.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 25 Indians 2 2010-04-01 2010-04-01 false Responsibility of dealer. 304.6 Section 304.6 Indians INDIAN ARTS AND CRAFTS BOARD, DEPARTMENT OF THE INTERIOR NAVAJO, PUEBLO, AND HOPI SILVER, USE OF GOVERNMENT MARK § 304.6 Responsibility of dealer. All dies will be numbered, and each wholesaler or dealer...

31 CFR 560.304 - Government of Iran.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Government of Iran. 560.304 Section 560.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF... § 560.304 Government of Iran. The term Government of Iran includes: (a) The state and the Government of...

44 CFR 304.5 - Audits and records.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Audits and records. 304.5 Section 304.5 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS CONSOLIDATED GRANTS TO INSULAR AREAS § 304.5 Audits and records. (a) Audits. FEMA will maintain adequate auditing,...

33 CFR 20.304 - Service of documents.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 33 Navigation and Navigable Waters 1 2011-07-01 2011-07-01 false Service of documents. 20.304 Section 20.304 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY GENERAL RULES... Pleadings and Motions § 20.304 Service of documents. (a) The ALJ shall serve upon each party to the...

48 CFR 801.304 - Department control and compliance procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... compliance procedures. 801.304 Section 801.304 Federal Acquisition Regulations System DEPARTMENT OF VETERANS... Regulations 801.304 Department control and compliance procedures. The Assistant Secretary for Management is... responsible for amending the VAAR for compliance with FAR 1.304. ...

Optical activity of the flaring gamma-ray blazar PKS 0458-02

NASA Astrophysics Data System (ADS)

Pursimo, Tapio; Ojha, Roopesh; Kiaeerad, Fatemeh

2012-09-01

We report optical photometry of the high redshift (z=2.286 Strittmatter et al. 1974, ApJ, 190, 509) flat spectrum radio quasar PKS 0458-02 obtained with the 2.56m Nordic Optical Telescope in La Palma. This superluminal FSRQ (apparent speed of 16.51c; Lister et al. 2009, AJ, 138,1874), is also known as 2FGL J0501.2-0155 (Nolan et al. 2012, ApJS, 199, 31) and was reported to be 30 times brighter than its average daily Fermi/LAT (E > 100 MeV) flux on 17 September (Atel#4396).

Confirming the gamma-ray blazar nature of the low energy counterpart QSO PKS1725+123 of 2FGL J1727.9+1220 with WISE

NASA Astrophysics Data System (ADS)

Massaro, F.; Paggi, A.; D'Abrusco, R.

2012-06-01

Following the near infrared NIR brightening of the QSO PKS1725+123 (=BZQJ1728+1215) (ATEL #4201), associated to the gamma-ray source 2FGL J1727.9+1220 in Nolan et al. (2012 ApJS, 199, 31), we searched in the Wide-field Infrared Survey Explorer (WISE; Wright et al. 2010 AJ, 140, 1868) catalog at the VLBI position of the QSO PKS1725+123 (R.A.(J2000): 17h28m07.0512s, Dec.(J2000): +12d15m39.485s) reported in Beasley et al.

48 CFR 2801.304 - Agency control and compliance procedures.

Code of Federal Regulations, 2010 CFR

2010-10-01

... compliance procedures. 2801.304 Section 2801.304 Federal Acquisition Regulations System DEPARTMENT OF JUSTICE General DEPARTMENT OF JUSTICE ACQUISITION REGULATIONS SYSTEM Agency Acquisition Regulations 2801.304 Agency control and compliance procedures. Pursuant to FAR 1.304, the Procurement Executive (PE) is...

29 CFR 1614.304 - Contents of petition.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 29 Labor 4 2010-07-01 2010-07-01 false Contents of petition. 1614.304 Section 1614.304 Labor Regulations Relating to Labor (Continued) EQUAL EMPLOYMENT OPPORTUNITY COMMISSION FEDERAL SECTOR EQUAL EMPLOYMENT OPPORTUNITY Related Processes § 1614.304 Contents of petition. (a) Form. Petitions must be written or typed, but may use any format includin...

The First GeV Outburst of the Radio-loud Narrow-line Seyfert 1 Galaxy PKS 1502+036

NASA Astrophysics Data System (ADS)

Paliya, Vaidehi S.; Stalin, C. S.

2016-03-01

The γ-ray-loud narrow-line Seyfert 1 (γ-NLSy1) galaxy PKS 1502+036 (z = 0.409) exhibited its first γ-ray outburst on 2015 December 20. In the energy range of 0.1-300 GeV, the highest flux measured by the Fermi-Large Area Telescope is (3.90 ± 1.52) × 10-6 {ph} {{cm}}-2 {{{s}}}-1, which is the highest γ-ray flux ever detected from this object. The associated spectral shape is soft (Γ0.1-300 GeV = 2.57 ± 0.17) and this corresponds to an isotropic γ-ray luminosity of (1.2 ± 0.6) × 1048 erg s-1. We generate the broadband spectral energy distribution (SED) during the GeV flare and reproduce it using a one-zone leptonic emission model. The optical-UV spectrum can be explained by a combination of synchrotron and accretion disk emission, whereas the X-ray-to-γ-ray SED can be satisfactorily reproduced by inverse-Compton scattering of thermal photons that originated from the torus. The derived SED parameters hint that the increase in the bulk Lorentz factor is a major cause of the flare and the location of the emission region is estimated as being outside the broad-line region but still inside the torus. A comparison of the GeV-flaring SED of PKS 1502+036 with that of two other γ-NLSy1 galaxies, namely, 1H 0323+342 (z = 0.061) and PMN J0948+0022 (z = 0.585), and also with flat spectrum radio quasar (FSRQ) 3C 279 (z = 0.536), has led to the conclusion that the GeV-flaring SEDs of γ-NLSy1 galaxies resemble FSRQs and a major fraction of their bolometric luminosities are emitted at γ-ray energies.

24 CFR 51.304 - Responsibilities.

Code of Federal Regulations, 2010 CFR

2010-04-01

... ENVIRONMENTAL CRITERIA AND STANDARDS Siting of HUD Assisted Projects in Runway Clear Zones at Civil Airports and Clear Zones and Accident Potential Zones at Military Airfields § 51.304 Responsibilities. (a) The... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Responsibilities. 51.304 Section 51...

24 CFR 51.304 - Responsibilities.

Code of Federal Regulations, 2013 CFR

2013-04-01

... ENVIRONMENTAL CRITERIA AND STANDARDS Siting of HUD Assisted Projects in Runway Clear Zones at Civil Airports and Clear Zones and Accident Potential Zones at Military Airfields § 51.304 Responsibilities. (a) The... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Responsibilities. 51.304 Section 51...

24 CFR 51.304 - Responsibilities.

Code of Federal Regulations, 2012 CFR

2012-04-01

... ENVIRONMENTAL CRITERIA AND STANDARDS Siting of HUD Assisted Projects in Runway Clear Zones at Civil Airports and Clear Zones and Accident Potential Zones at Military Airfields § 51.304 Responsibilities. (a) The... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Responsibilities. 51.304 Section 51...

24 CFR 51.304 - Responsibilities.

Code of Federal Regulations, 2014 CFR

2014-04-01

... ENVIRONMENTAL CRITERIA AND STANDARDS Siting of HUD Assisted Projects in Runway Clear Zones at Civil Airports and Clear Zones and Accident Potential Zones at Military Airfields § 51.304 Responsibilities. (a) The... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Responsibilities. 51.304 Section 51...

24 CFR 51.304 - Responsibilities.

Code of Federal Regulations, 2011 CFR

2011-04-01

... ENVIRONMENTAL CRITERIA AND STANDARDS Siting of HUD Assisted Projects in Runway Clear Zones at Civil Airports and Clear Zones and Accident Potential Zones at Military Airfields § 51.304 Responsibilities. (a) The... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Responsibilities. 51.304 Section 51...

21 CFR 556.304 - Gonadotropin.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 21 Food and Drugs 6 2011-04-01 2011-04-01 false Gonadotropin. 556.304 Section 556.304 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS TOLERANCES FOR RESIDUES OF NEW ANIMAL DRUGS IN FOOD Specific Tolerances for...

21 CFR 556.304 - Gonadotropin.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Gonadotropin. 556.304 Section 556.304 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS TOLERANCES FOR RESIDUES OF NEW ANIMAL DRUGS IN FOOD Specific Tolerances for...

1 CFR 304.2 - Public reading room.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 1 General Provisions 1 2012-01-01 2012-01-01 false Public reading room. 304.2 Section 304.2 General Provisions ADMINISTRATIVE CONFERENCE OF THE UNITED STATES DISCLOSURE OF RECORDS OR INFORMATION Procedures for Disclosure of Records Under the Freedom of Information Act § 304.2 Public reading room. (a) ACUS maintains a public reading room that...

1 CFR 304.2 - Public reading room.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 1 General Provisions 1 2013-01-01 2012-01-01 true Public reading room. 304.2 Section 304.2 General Provisions ADMINISTRATIVE CONFERENCE OF THE UNITED STATES DISCLOSURE OF RECORDS OR INFORMATION Procedures for Disclosure of Records Under the Freedom of Information Act § 304.2 Public reading room. (a) ACUS maintains a public reading room that...

1 CFR 304.2 - Public reading room.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 1 General Provisions 1 2014-01-01 2012-01-01 true Public reading room. 304.2 Section 304.2 General Provisions ADMINISTRATIVE CONFERENCE OF THE UNITED STATES DISCLOSURE OF RECORDS OR INFORMATION Procedures for Disclosure of Records Under the Freedom of Information Act § 304.2 Public reading room. (a) ACUS maintains a public reading room that...

22 CFR 304.10 - Review of claim.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Review of claim. 304.10 Section 304.10 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.10 Review of... the written determination. [34 FR 5840, Mar. 28, 1969, as amended at 73 FR 21528, Apr. 22, 2008; 73 FR...

22 CFR 304.10 - Review of claim.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Review of claim. 304.10 Section 304.10 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.10 Review of... the written determination. [34 FR 5840, Mar. 28, 1969, as amended at 73 FR 21528, Apr. 22, 2008; 73 FR...

CCD photometry of 1218+304 1219+28 and 1727+50: Point sources, associated nebulosity and broadband spectra

NASA Technical Reports Server (NTRS)

Weistrop, D.; Shaffer, D. B.; Mushotzky, R. F.; Reitsma, H. J.; Smith, B. A.

1981-01-01

Visual and far red surface photometry were obtained of two X-ray emitting BL Lacertae objects, 1218+304 (2A1219+305) and 1727+50 (Izw 187), as well as the highly variable object 1219+28 (ON 231, W Com). The intensity distribution for 1727+50 can be modeled using a central point source plus a de Vaucouleurs intensity law for an underlying galaxy. The broad band spectral energy distribution so derived is consistent with what is expected for an elliptical galaxy. The spectral index of the point source is alpha = 0.97. Additional VLBI and X-ray data are also reported for 1727+50. There is nebulosity associated with the recently discovered object 1218+304. No nebulosity is found associated with 1219+28. A comparison of the results with observations at X-ray and radio frequencies suggests that all the emission from 1727+50 and 1218+304 can be interpreted as due solely to direct synchrotron emission. If this is the case, the data further imply the existence of relativistic motion effects and continuous particle injection.

31 CFR 551.304 - Interest.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 31 Money and Finance:Treasury 3 2011-07-01 2011-07-01 false Interest. 551.304 Section 551.304... Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct or indirect. ...

31 CFR 551.304 - Interest.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Interest. 551.304 Section 551.304... Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct or indirect. ...

31 CFR 552.304 - Interest.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Interest. 552.304 Section 552.304... Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct or indirect. ...

31 CFR 551.304 - Interest.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Interest. 551.304 Section 551.304... Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct or indirect. ...

31 CFR 551.304 - Interest.

Code of Federal Regulations, 2014 CFR

2014-07-01

... 31 Money and Finance:Treasury 3 2014-07-01 2014-07-01 false Interest. 551.304 Section 551.304... Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct or indirect. ...

31 CFR 552.304 - Interest.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Interest. 552.304 Section 552.304... Interest. Except as otherwise provided in this part, the term interest, when used with respect to property (e.g., “an interest in property”), means an interest of any nature whatsoever, direct or indirect. ...

Identification of a hybrid PKS-NRPS required for the biosynthesis of NG-391 in Metarhizium anisopliae var. anisopliae

USDA-ARS?s Scientific Manuscript database

A 19,818 kb genomic region harboring six predicted ORFs was identified in M. anisopliae ARSEF 2575. ORF4, putatively encoding a hybrid polyketide synthase-nonribosomal peptide synthetase (PKS-NRPS) was targeted using Agrobacterium-mediated gene knockout. Homologous recombinants failed to produce det...

48 CFR 49.304 - Procedure for partial termination.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Procedure for partial termination. 49.304 Section 49.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION... Terminated for Convenience 49.304 Procedure for partial termination. ...

5 CFR 950.304 - Responsibilities of local federations.

Code of Federal Regulations, 2011 CFR

2011-01-01

... CONTRIBUTIONS TO PRIVATE VOLUNTARY ORGANIZATIONS Federations § 950.304 Responsibilities of local federations. (a) Local federations must ensure that only those member organizations that comply with all eligibility.... 950.304 Section 950.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL...

5 CFR 950.304 - Responsibilities of local federations.

Code of Federal Regulations, 2010 CFR

2010-01-01

... CONTRIBUTIONS TO PRIVATE VOLUNTARY ORGANIZATIONS Federations § 950.304 Responsibilities of local federations. (a) Local federations must ensure that only those member organizations that comply with all eligibility.... 950.304 Section 950.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL...

5 CFR 950.304 - Responsibilities of local federations.

Code of Federal Regulations, 2012 CFR

2012-01-01

... CONTRIBUTIONS TO PRIVATE VOLUNTARY ORGANIZATIONS Federations § 950.304 Responsibilities of local federations. (a) Local federations must ensure that only those member organizations that comply with all eligibility.... 950.304 Section 950.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL...

5 CFR 950.304 - Responsibilities of local federations.

Code of Federal Regulations, 2013 CFR

2013-01-01

... CONTRIBUTIONS TO PRIVATE VOLUNTARY ORGANIZATIONS Federations § 950.304 Responsibilities of local federations. (a) Local federations must ensure that only those member organizations that comply with all eligibility.... 950.304 Section 950.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL...

5 CFR 950.304 - Responsibilities of local federations.

Code of Federal Regulations, 2014 CFR

2014-01-01

... CONTRIBUTIONS TO PRIVATE VOLUNTARY ORGANIZATIONS Federations § 950.304 Responsibilities of local federations. (a) Local federations must ensure that only those member organizations that comply with all eligibility.... 950.304 Section 950.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL...

48 CFR 47.304 - Determination of delivery terms.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Determination of delivery terms. 47.304 Section 47.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TRANSPORTATION Transportation in Supply Contracts 47.304 Determination of delivery...

40 CFR 304.33 - Arbitral decision and public comment.

Code of Federal Regulations, 2010 CFR

2010-07-01

.... 304.33 Section 304.33 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND... RECOVERY CLAIMS Hearings Before the Arbitrator § 304.33 Arbitral decision and public comment. (a) The... jurisdiction as defined by § 304.20 of this part, and shall, if such issues have been jointly submitted by the...

48 CFR 29.304 - Matters requiring special consideration.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false Matters requiring special consideration. 29.304 Section 29.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS TAXES State and Local Taxes 29.304 Matters requiring special...

48 CFR 29.304 - Matters requiring special consideration.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false Matters requiring special consideration. 29.304 Section 29.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS TAXES State and Local Taxes 29.304 Matters requiring special...

48 CFR 29.304 - Matters requiring special consideration.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 1 2012-10-01 2012-10-01 false Matters requiring special consideration. 29.304 Section 29.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS TAXES State and Local Taxes 29.304 Matters requiring special...

48 CFR 29.304 - Matters requiring special consideration.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Matters requiring special consideration. 29.304 Section 29.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS TAXES State and Local Taxes 29.304 Matters requiring special...

48 CFR 29.304 - Matters requiring special consideration.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Matters requiring special consideration. 29.304 Section 29.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION GENERAL CONTRACTING REQUIREMENTS TAXES State and Local Taxes 29.304 Matters requiring special...

48 CFR 606.304 - Approval of the justification.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 4 2011-10-01 2011-10-01 false Approval of the justification. 606.304 Section 606.304 Federal Acquisition Regulations System DEPARTMENT OF STATE COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 606.304...

48 CFR 46.304 - Fixed-price service contracts.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Fixed-price service contracts. 46.304 Section 46.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT QUALITY ASSURANCE Contract Clauses 46.304 Fixed-price service contracts. The...

5 CFR 430.304 - SES performance management systems.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 1 2011-01-01 2011-01-01 false SES performance management systems. 430.304 Section 430.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PERFORMANCE MANAGEMENT Managing Senior Executive Performance § 430.304 SES performance management systems. (a...

13 CFR 304.3 - District modification and termination.

Code of Federal Regulations, 2010 CFR

2010-01-01

... termination. 304.3 Section 304.3 Business Credit and Assistance ECONOMIC DEVELOPMENT ADMINISTRATION, DEPARTMENT OF COMMERCE ECONOMIC DEVELOPMENT DISTRICTS § 304.3 District modification and termination. (a... for economic development. (b) Termination. EDA may, upon sixty (60) days prior written notice to the...

7 CFR 22.304 - Multiyear planning and programming.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 1 2012-01-01 2012-01-01 false Multiyear planning and programming. 22.304 Section 22.304 Agriculture Office of the Secretary of Agriculture RURAL DEVELOPMENT COORDINATION Roles and Responsibilities of State Governments § 22.304 Multiyear planning and programming. State and multicounty...

7 CFR 22.304 - Multiyear planning and programming.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 1 2014-01-01 2014-01-01 false Multiyear planning and programming. 22.304 Section 22.304 Agriculture Office of the Secretary of Agriculture RURAL DEVELOPMENT COORDINATION Roles and Responsibilities of State Governments § 22.304 Multiyear planning and programming. State and multicounty...

7 CFR 22.304 - Multiyear planning and programming.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 1 2013-01-01 2013-01-01 false Multiyear planning and programming. 22.304 Section 22.304 Agriculture Office of the Secretary of Agriculture RURAL DEVELOPMENT COORDINATION Roles and Responsibilities of State Governments § 22.304 Multiyear planning and programming. State and multicounty...

48 CFR 6.304 - Approval of the justification.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Approval of the justification. 6.304 Section 6.304 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 6.304 Approval of the...

48 CFR 1406.304 - Approval of the justification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Approval of the justification. 1406.304 Section 1406.304 Federal Acquisition Regulations System DEPARTMENT OF THE INTERIOR COMPETITION AND ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 1406.304...

45 CFR 304.24 - Equipment-Federal financial participation.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false Equipment-Federal financial participation. 304.24 Section 304.24 Public Welfare Regulations Relating to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT... HUMAN SERVICES FEDERAL FINANCIAL PARTICIPATION § 304.24 Equipment—Federal financial participation...

48 CFR 906.304 - Approval of the justification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Approval of the justification. 906.304 Section 906.304 Federal Acquisition Regulations System DEPARTMENT OF ENERGY COMPETITION ACQUISITION PLANNING COMPETITION REQUIREMENTS Other Than Full and Open Competition 906.304 Approval of the...

7 CFR 22.304 - Multiyear planning and programming.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 1 2010-01-01 2010-01-01 false Multiyear planning and programming. 22.304 Section 22.304 Agriculture Office of the Secretary of Agriculture RURAL DEVELOPMENT COORDINATION Roles and Responsibilities of State Governments § 22.304 Multiyear planning and programming. State and multicounty...

7 CFR 22.304 - Multiyear planning and programming.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 1 2011-01-01 2011-01-01 false Multiyear planning and programming. 22.304 Section 22.304 Agriculture Office of the Secretary of Agriculture RURAL DEVELOPMENT COORDINATION Roles and Responsibilities of State Governments § 22.304 Multiyear planning and programming. State and multicounty...

22 CFR 1203.735-304 - Coercion.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Coercion. 1203.735-304 Section 1203.735-304 Foreign Relations UNITED STATES INTERNATIONAL DEVELOPMENT COOPERATION AGENCY EMPLOYEE RESPONSIBILITIES AND... one with whom the employee has family, business, or financial ties. ...

[Screening and characterization of marine bacteria with antibacterial and cytotoxic activities, and existence of PKS I and NRPS genes in bioactive strains].

PubMed

Zhu, Peng; Zheng, Li; Li, Jing; Shao, Jian-zhong; Yan, Xiao-jun

2007-04-01

Antibacterial and cytotoxic activities were screened for marine bacteria which have been isolated from organism, sediments and seawater in China coastal area. The results showed that 42 isolates had antimicrobial activity and 12 isolates had cytotoxicity. Molecular phylogenetic analysis of marine bacteria with cytotoxicity based on 16S rRNA sequences indicated that they were belong to the genera Aerococcus, Agrobacterium, Alteromona, Bacillus, Exiguobacterium, Paracoccus, Pseudoalteromons, Rheinheimera. Furthermore, marine bacteria with cytotoxicity were also screened for PKS I and NRPS genes which could be responsible for bioactive secondary metabolites biosynthesis, 4 strains having KS domain or A domain were obtained, which provide strong evidence that marine bioactive bacteria can produce natural products through PKS and NRPS pathways.

48 CFR 304.804-70 - Contract closeout audits.

Code of Federal Regulations, 2012 CFR

2012-10-01

... 48 Federal Acquisition Regulations System 4 2012-10-01 2012-10-01 false Contract closeout audits. 304.804-70 Section 304.804-70 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATIVE MATTERS Government Contract Files 304.804-70 Contract closeout audits. (a) Contracting Officers...

48 CFR 304.804-70 - Contract closeout audits.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 4 2014-10-01 2014-10-01 false Contract closeout audits. 304.804-70 Section 304.804-70 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATIVE MATTERS Government Contract Files 304.804-70 Contract closeout audits. (a) Contracting Officers...

48 CFR 304.804-70 - Contract closeout audits.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 4 2013-10-01 2013-10-01 false Contract closeout audits. 304.804-70 Section 304.804-70 Federal Acquisition Regulations System HEALTH AND HUMAN SERVICES GENERAL ADMINISTRATIVE MATTERS Government Contract Files 304.804-70 Contract closeout audits. (a) Contracting Officers...

48 CFR 2406.304 - Approval of the justification.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Approval of the justification. 2406.304 Section 2406.304 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN... 2406.304 Approval of the justification. (c) A class justification for other than full and open...

45 CFR 304.29 - Applicability of other regulations.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false Applicability of other regulations. 304.29 Section 304.29 Public Welfare Regulations Relating to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT... HUMAN SERVICES FEDERAL FINANCIAL PARTICIPATION § 304.29 Applicability of other regulations. Sections 201...

40 CFR 304.32 - Arbitral hearing.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 29 2013-07-01 2013-07-01 false Arbitral hearing. 304.32 Section 304.32 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS ARBITRATION PROCEDURES FOR SMALL SUPERFUND COST RECOVERY...

40 CFR 304.42 - Miscellaneous provisions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 40 Protection of Environment 28 2011-07-01 2011-07-01 false Miscellaneous provisions. 304.42 Section 304.42 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS ARBITRATION PROCEDURES FOR SMALL SUPERFUND COST RECOVERY...

40 CFR 304.42 - Miscellaneous provisions.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 40 Protection of Environment 29 2013-07-01 2013-07-01 false Miscellaneous provisions. 304.42 Section 304.42 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS ARBITRATION PROCEDURES FOR SMALL SUPERFUND COST RECOVERY...

40 CFR 304.42 - Miscellaneous provisions.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 29 2012-07-01 2012-07-01 false Miscellaneous provisions. 304.42 Section 304.42 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS ARBITRATION PROCEDURES FOR SMALL SUPERFUND COST RECOVERY...

40 CFR 304.32 - Arbitral hearing.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 40 Protection of Environment 29 2012-07-01 2012-07-01 false Arbitral hearing. 304.32 Section 304.32 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SUPERFUND, EMERGENCY PLANNING, AND COMMUNITY RIGHT-TO-KNOW PROGRAMS ARBITRATION PROCEDURES FOR SMALL SUPERFUND COST RECOVERY...

48 CFR 49.304-1 - General.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false General. 49.304-1 Section 49.304-1 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION CONTRACT MANAGEMENT TERMINATION OF CONTRACTS Additional Principles for Cost-Reimbursement Contracts Terminated for Convenience 49...

7 CFR 718.304 - Failure to fully comply.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 7 2010-01-01 2010-01-01 false Failure to fully comply. 718.304 Section 718.304 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF... MULTIPLE PROGRAMS Equitable Relief From Ineligibility § 718.304 Failure to fully comply. (a) Under a...

7 CFR 718.304 - Failure to fully comply.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 7 2011-01-01 2011-01-01 false Failure to fully comply. 718.304 Section 718.304 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF... MULTIPLE PROGRAMS Equitable Relief From Ineligibility § 718.304 Failure to fully comply. (a) Under a...

31 CFR 594.304 - Foreign person.

Code of Federal Regulations, 2013 CFR

2013-07-01

... 31 Money and Finance:Treasury 3 2013-07-01 2013-07-01 false Foreign person. 594.304 Section 594.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS REGULATIONS General...

31 CFR 594.304 - Foreign person.

Code of Federal Regulations, 2012 CFR

2012-07-01

... 31 Money and Finance:Treasury 3 2012-07-01 2012-07-01 false Foreign person. 594.304 Section 594.304 Money and Finance: Treasury Regulations Relating to Money and Finance (Continued) OFFICE OF FOREIGN ASSETS CONTROL, DEPARTMENT OF THE TREASURY GLOBAL TERRORISM SANCTIONS REGULATIONS General...

34 CFR 304.21 - Allowable costs.

Code of Federal Regulations, 2011 CFR

2011-07-01

... 34 Education 2 2011-07-01 2010-07-01 true Allowable costs. 304.21 Section 304.21 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION SERVICE OBLIGATIONS UNDER SPECIAL EDUCATION-PERSONNEL...

34 CFR 304.21 - Allowable costs.

Code of Federal Regulations, 2010 CFR

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false Allowable costs. 304.21 Section 304.21 Education Regulations of the Offices of the Department of Education (Continued) OFFICE OF SPECIAL EDUCATION AND REHABILITATIVE SERVICES, DEPARTMENT OF EDUCATION SERVICE OBLIGATIONS UNDER SPECIAL EDUCATION-PERSONNEL...

13 CFR 304.4 - Performance evaluations.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 13 Business Credit and Assistance 1 2011-01-01 2011-01-01 false Performance evaluations. 304.4... ECONOMIC DEVELOPMENT DISTRICTS § 304.4 Performance evaluations. (a) EDA shall evaluate the management standards, financial accountability and program performance of each District Organization within three (3...

13 CFR 304.4 - Performance evaluations.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 13 Business Credit and Assistance 1 2014-01-01 2014-01-01 false Performance evaluations. 304.4... ECONOMIC DEVELOPMENT DISTRICTS § 304.4 Performance evaluations. (a) EDA shall evaluate the management standards, financial accountability and program performance of each District Organization within three (3...

13 CFR 304.4 - Performance evaluations.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 13 Business Credit and Assistance 1 2013-01-01 2013-01-01 false Performance evaluations. 304.4... ECONOMIC DEVELOPMENT DISTRICTS § 304.4 Performance evaluations. (a) EDA shall evaluate the management standards, financial accountability and program performance of each District Organization within three (3...

7 CFR 1250.304 - Egg Board or Board.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 7 Agriculture 10 2010-01-01 2010-01-01 false Egg Board or Board. 1250.304 Section 1250.304... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE EGG RESEARCH AND PROMOTION Egg Research and Promotion Order Definitions § 1250.304 Egg Board or Board. Egg Board or Board or other...

45 CFR 304.11 - Effect of State rules.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false Effect of State rules. 304.11 Section 304.11 Public Welfare Regulations Relating to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT (CHILD SUPPORT... FEDERAL FINANCIAL PARTICIPATION § 304.11 Effect of State rules. Subject to the provisions and limitations...

45 CFR 304.50 - Treatment of program income.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 45 Public Welfare 2 2011-10-01 2011-10-01 false Treatment of program income. 304.50 Section 304.50 Public Welfare Regulations Relating to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT (CHILD SUPPORT... FEDERAL FINANCIAL PARTICIPATION § 304.50 Treatment of program income. The IV-D agency must exclude from...

45 CFR 304.11 - Effect of State rules.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false Effect of State rules. 304.11 Section 304.11 Public Welfare Regulations Relating to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT (CHILD SUPPORT... FEDERAL FINANCIAL PARTICIPATION § 304.11 Effect of State rules. Subject to the provisions and limitations...

45 CFR 304.50 - Treatment of program income.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 45 Public Welfare 2 2010-10-01 2010-10-01 false Treatment of program income. 304.50 Section 304.50 Public Welfare Regulations Relating to Public Welfare OFFICE OF CHILD SUPPORT ENFORCEMENT (CHILD SUPPORT... FEDERAL FINANCIAL PARTICIPATION § 304.50 Treatment of program income. The IV-D agency must exclude from...

7 CFR 1250.304 - Egg Board or Board.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 7 Agriculture 10 2011-01-01 2011-01-01 false Egg Board or Board. 1250.304 Section 1250.304... AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE EGG RESEARCH AND PROMOTION Egg Research and Promotion Order Definitions § 1250.304 Egg Board or Board. Egg Board or Board or other...

22 CFR 304.12 - Action on approved claim.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Action on approved claim. 304.12 Section 304.12 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.12 Action on approved claim. (a) Payment of a claim approved under this subpart is contingent on claimant's...

22 CFR 304.11 - Final denial of claim.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 22 Foreign Relations 2 2011-04-01 2009-04-01 true Final denial of claim. 304.11 Section 304.11 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.11 Final denial of claim. The General Counsel will send notification of the final denial of an...

22 CFR 304.12 - Action on approved claim.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Action on approved claim. 304.12 Section 304.12 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.12 Action on approved claim. (a) Payment of a claim approved under this subpart is contingent on claimant's...

22 CFR 304.11 - Final denial of claim.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 22 Foreign Relations 2 2014-04-01 2014-04-01 false Final denial of claim. 304.11 Section 304.11 Foreign Relations PEACE CORPS CLAIMS AGAINST GOVERNMENT UNDER FEDERAL TORT CLAIMS ACT Procedures § 304.11 Final denial of claim. The General Counsel will send notification of the final denial of an...

10 CFR 1015.304 - Joint and several liability.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 10 Energy 4 2011-01-01 2011-01-01 false Joint and several liability. 1015.304 Section 1015.304 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) COLLECTION OF CLAIMS OWED THE UNITED STATES Standards for the Compromise of Claims § 1015.304 Joint and several liability. (a) When two or more debtors are...

7 CFR 718.304 - Failure to fully comply.

Code of Federal Regulations, 2013 CFR

2013-01-01

... 7 Agriculture 7 2013-01-01 2013-01-01 false Failure to fully comply. 718.304 Section 718.304... MULTIPLE PROGRAMS Equitable Relief From Ineligibility § 718.304 Failure to fully comply. (a) Under a covered program, when the failure of a participant to fully comply with the terms and conditions of a...

7 CFR 718.304 - Failure to fully comply.

Code of Federal Regulations, 2014 CFR

2014-01-01

... 7 Agriculture 7 2014-01-01 2014-01-01 false Failure to fully comply. 718.304 Section 718.304... MULTIPLE PROGRAMS Equitable Relief From Ineligibility § 718.304 Failure to fully comply. (a) Under a covered program, when the failure of a participant to fully comply with the terms and conditions of a...

7 CFR 718.304 - Failure to fully comply.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 7 Agriculture 7 2012-01-01 2012-01-01 false Failure to fully comply. 718.304 Section 718.304... MULTIPLE PROGRAMS Equitable Relief From Ineligibility § 718.304 Failure to fully comply. (a) Under a covered program, when the failure of a participant to fully comply with the terms and conditions of a...

20 CFR 638.304 - Historical preservation.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Historical preservation. 638.304 Section 638.304 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR JOB CORPS PROGRAM UNDER TITLE IV-B OF THE JOB TRAINING PARTNERSHIP ACT Funding, Site Selection, and Facilities Management...

48 CFR 37.304 - Contract clauses.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Contract clauses. 37.304... CONTRACTING SERVICE CONTRACTING Dismantling, Demolition, or Removal of Improvements 37.304 Contract clauses. (a) The contracting officer shall insert the clause at 52.237-4, Payment by Government to Contractor...

5 CFR 880.304 - FEGLI coverage.

Code of Federal Regulations, 2012 CFR

2012-01-01

... 5 Administrative Personnel 2 2012-01-01 2012-01-01 false FEGLI coverage. 880.304 Section 880.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED... FEGLI coverage. (a) FEGLI premiums will not be collected during periods when an annuitant is a missing...

5 CFR 880.304 - FEGLI coverage.

Code of Federal Regulations, 2011 CFR

2011-01-01

... 5 Administrative Personnel 2 2011-01-01 2011-01-01 false FEGLI coverage. 880.304 Section 880.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED... FEGLI coverage. (a) FEGLI premiums will not be collected during periods when an annuitant is a missing...

5 CFR 880.304 - FEGLI coverage.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false FEGLI coverage. 880.304 Section 880.304 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL SERVICE REGULATIONS (CONTINUED... FEGLI coverage. (a) FEGLI premiums will not be collected during periods when an annuitant is a missing...

5 CFR 304.104 - Determining rate of pay.

Code of Federal Regulations, 2010 CFR

2010-01-01

... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Determining rate of pay. 304.104 Section... CONSULTANT APPOINTMENTS § 304.104 Determining rate of pay. (a) The rate of basic pay for experts and... appropriate rate of basic pay on an hourly or daily basis, subject to the limitations described in section 304...

The host galaxy of the γ-ray-emitting narrow-line Seyfert 1 galaxy PKS 1502+036

NASA Astrophysics Data System (ADS)

D'Ammando, F.; Acosta-Pulido, J. A.; Capetti, A.; Baldi, R. D.; Orienti, M.; Raiteri, C. M.; Ramos Almeida, C.

2018-07-01

The detection of γ-ray emission from narrow-line Seyfert 1 galaxies (NLSy1) has challenged the idea that large black hole (BH) masses (≥108 M⊙) are needed to launch relativistic jets. We present near-infrared imaging data of the γ-ray-emitting NLSy1 PKS 1502+036 obtained with the Very Large Telescope. Its surface brightness profile, extending to ˜20 kpc, is well described by the combination of a nuclear component and a bulge with a Sérsic index n = 3.5, which is indicative of an elliptical galaxy. A circumnuclear structure observed near PKS 1502+036 may be the result of galaxy interactions. A BH mass of ˜7 × 108 M⊙ has been estimated by the bulge luminosity. The presence of an additional faint disc component cannot be ruled out with the present data, but this would reduce the BH mass estimate by only ˜30 per cent. These results, together with analogous findings obtained for FBQS J1644+2619, indicate that the relativistic jets in γ-ray-emitting NLSy1 are likely produced by massive black holes at the centre of elliptical galaxies.

The host galaxy of the γ-ray-emitting narrow-line Seyfert 1 galaxy PKS 1502+036

NASA Astrophysics Data System (ADS)

D'Ammando, F.; Acosta-Pulido, J. A.; Capetti, A.; Baldi, R. D.; Orienti, M.; Raiteri, C. M.; Ramos Almeida, C.

2018-04-01

The detection of γ-ray emission from narrow-line Seyfert 1 galaxies (NLSy1) has challenged the idea that large black hole (BH) masses (≥108 M⊙) are needed to launch relativistic jets. We present near-infrared imaging data of the γ-ray-emitting NLSy1 PKS 1502+036 obtained with the Very Large Telescope. Its surface brightness profile, extending to ˜ 20 kpc, is well described by the combination of a nuclear component and a bulge with a Sérsic index n = 3.5, which is indicative of an elliptical galaxy. A circumnuclear structure observed near PKS 1502+036 may be the result of galaxy interactions. A BH mass of ˜7 × 108 M⊙ has been estimated by the bulge luminosity. The presence of an additional faint disc component cannot be ruled out with the present data, but this would reduce the BH mass estimate by only ˜ 30%. These results, together with analogous findings obtained for FBQS J1644+2619, indicate that the relativistic jets in γ-ray-emitting NLSy1 are likely produced by massive black holes at the center of elliptical galaxies.

17 CFR 229.304 - (Item 304) Changes in and disagreements with accountants on accounting and financial disclosure.

Code of Federal Regulations, 2010 CFR

2010-04-01

... disagreements with accountants on accounting and financial disclosure. 229.304 Section 229.304 Commodity and... accounting and financial disclosure. (a)(1) If during the registrant's two most recent fiscal years or any... any matter of accounting principles or practices, financial statement disclosure, or auditing scope or...

25 CFR 304.5 - Dies to identify tribe.

Code of Federal Regulations, 2014 CFR

2014-04-01

... 25 Indians 2 2014-04-01 2014-04-01 false Dies to identify tribe. 304.5 Section 304.5 Indians INDIAN ARTS AND CRAFTS BOARD, DEPARTMENT OF THE INTERIOR NAVAJO, PUEBLO, AND HOPI SILVER, USE OF GOVERNMENT MARK § 304.5 Dies to identify tribe. Dies are marked with name of tribe. A Navajo stamp will be...

25 CFR 304.5 - Dies to identify tribe.

Code of Federal Regulations, 2011 CFR

2011-04-01

... 25 Indians 2 2011-04-01 2011-04-01 false Dies to identify tribe. 304.5 Section 304.5 Indians INDIAN ARTS AND CRAFTS BOARD, DEPARTMENT OF THE INTERIOR NAVAJO, PUEBLO, AND HOPI SILVER, USE OF GOVERNMENT MARK § 304.5 Dies to identify tribe. Dies are marked with name of tribe. A Navajo stamp will be...

25 CFR 304.5 - Dies to identify tribe.

Code of Federal Regulations, 2012 CFR

2012-04-01

... 25 Indians 2 2012-04-01 2012-04-01 false Dies to identify tribe. 304.5 Section 304.5 Indians INDIAN ARTS AND CRAFTS BOARD, DEPARTMENT OF THE INTERIOR NAVAJO, PUEBLO, AND HOPI SILVER, USE OF GOVERNMENT MARK § 304.5 Dies to identify tribe. Dies are marked with name of tribe. A Navajo stamp will be...