Using Separate Answer Sheets with Grade 3 Students

ERIC Educational Resources Information Center

Brooks, Thomas; O'Malley, Kimberly; Ragland, Shelley; Young, Michael; Kirkpatrick, Rob

2014-01-01

The authors compared the performance of third-grade students testing on answer sheets with those testing on machine-scored test booklets. The 1,832 students in the nationally representative sample were assigned at the campus level to complete the Stanford Achievement Test Series, Tenth Edition in 1 of 4 conditions: (a) Form A answer sheet, (b)…

Retailing. Instructor's Guide Sheets and Instructor's Package, Modules R 1-45. Competency-Based Education.

ERIC Educational Resources Information Center

Kentucky State Dept. of Education, Frankfort.

This package contains instructor's guide sheets and student task assignment sheets for Modules R 1-45 of the competency-based curriculum in retailing developed for use in secondary and postsecondary schools in Kentucky. Some of the topics covered in the modules include the following: retailing--past, present, and future; retailing occupations;…

76 FR 47550 - Certain Tissue Paper Products From the People's Republic of China: Notice of Rescission of the...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-05

... products produced from Chinese-origin jumbo rolls/ sheets.\\3\\ We determined in the Preliminary Results, as... paper products produced using Chinese-origin jumbo rolls/sheets. Further, based on AFA, we preliminarily... produced by MFVN from Chinese-origin jumbo rolls/sheets is China. Consequently, we assigned MFVN a cash...

14 CFR Section 6 - Objective Classification of Balance Sheet Elements

Code of Federal Regulations, 2010 CFR

2010-01-01

... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Objective Classification of Balance Sheet... AIR CARRIERS Balance Sheet Classifications Section 6 Objective Classification of Balance Sheet...) Record here all general and working funds available on demand as of the date of the balance sheet which...

14 CFR Section 6 - Objective Classification of Balance Sheet Elements

Code of Federal Regulations, 2011 CFR

2011-01-01

... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Objective Classification of Balance Sheet... AIR CARRIERS Balance Sheet Classifications Section 6 Objective Classification of Balance Sheet...) Record here all general and working funds available on demand as of the date of the balance sheet which...

Structure and luminescence properties of 10-BN sheets

NASA Astrophysics Data System (ADS)

Han, Wei-Qiang; Liu, Lijia; Sham, T. K.; Liu, Zhenxian

2012-10-01

Isotopic 10BN sheets were first prepared using graphene sheets as templates to react with 10B2O3. The edge-areas of BN sheets have much higher oxygen-doping ratios compared to other areas. The emission peak of X-ray excited optical luminescence spectra of the 10BN-sheets is broader and red-shifted because of the isotopic effect. A broad violet-blue emission at a wavelength centered at ~400 nm is assigned to the defect emission due to oxygen-doping and defects in the BN network.

Over the counter drugs (and dietary supplement) exercise: a team-based introduction to biochemistry for health professional students.

PubMed

Phadtare, Sangita; Abali, Emine; Brodsky, Barbara

2013-01-01

For successful delivery of basic science topics for health-professional students, it is critical to reduce apprehension and illustrate relevance to clinical settings and everyday life. At the beginning of the Biochemistry course for Physician Assistants, a team-based assignment was designed to develop an understanding of the mechanism of action, effectiveness, and toxicity of five common over the counter (OTC) drugs and dietary supplements, and place these familiar medicines in a political and historical context. The objectives of this exercise were to stimulate interest in biochemistry; to provide basic information on enzymes and enzyme inhibitors related to these drugs to be expanded upon later in the course; and to encourage active and interactive learning. Teams of five students were formed, and each student was given an information sheet on aspirin, alpha-galactosidase, orlistat, dextromethorphan, or simvastatin, a low dose statin, which was previously available without prescription at pharmacies in the UK. After each member of the team acquired information on one OTC drug/dietary supplement by reading an assigned information sheet, the team was asked to go through a series of questions, and then submit answers to a quiz as a group. A high rate of success on the quiz, an overwhelmingly positive response on formal course evaluations, and enthusiastic exchanges during class suggested this team-based session accomplished its goals. Copyright © 2013 Wiley-Liss, Inc.

Writing by Number: Teaching Students to Read the Balance Sheet.

ERIC Educational Resources Information Center

Cross, Mary

1990-01-01

Describes an assignment in which students write a short memo report analyzing and comparing both what a company says in its annual report and what its balance sheet shows. Describes four simple mathematical formulas students can use to quickly diagnose a company's financial health. Appends a sample of the short report format. (RS)

A Multidisciplinary First-Year Seminar about Tuberculosis.

ERIC Educational Resources Information Center

Fluck, Richard A.

2001-01-01

Describes a writing intensive seminar for college freshman. Includes goals, reading assignments, writing assignments, and group projects. Provides web-based resources on tuberculosis along with an evaluation sheet for web site reviews. Concludes that students exhibited great interest in the topic and course feedback was positive. (DLH)

Method and apparatus for assessing material properties of sheet-like materials

DOEpatents

Telschow, Kenneth L.; Deason, Vance A.

2002-01-01

Apparatus for producing an indication of a material property of a sheet-like material according to the present invention may comprise an excitation source for vibrating the sheet-like material to produce at least one traveling wave therein. A light source configured to produce an object wavefront and a reference wavefront directs the object wavefront toward the sheet-like material to produce a modulated object wavefront. A modulator operatively associated with the reference wavefront modulates the reference wavefront in synchronization with the traveling wave on the sheet-like material to produce a modulated reference wavefront. A sensing medium positioned to receive the modulated object wavefront and the modulated reference wavefront produces an image of the traveling wave in the sheet-like material, the image of the anti-symmetric traveling wave being related to a displacement amplitude of the anti-symmetric traveling wave over a two-dimensional area of the vibrating sheet-like material. A detector detects the image of the traveling wave in the sheet-like material.

The Effect on One's Own Performance of Evaluating Peers.

ERIC Educational Resources Information Center

Cohen, Stuart J.

Fifty-three high school males took a minicourse on library usage. All were randomly assigned a topic and given response sheets requiring the use of dictionaries, encyclopedias, periodicals, and books. In a discussion session, all received instructional handouts. Students were assigned either to evaluating two peers' pretests (experimental) or…

ELECTRICAL AND ELECTRONIC INDUSTRIAL CONTROL. D-C MAGNETIC MOTOR CONTROL, UNIT 7, ASSIGNMENTS.

ERIC Educational Resources Information Center

SUTTON, MACK C.

THIS GUIDE IS FOR INDIVIDUAL STUDENT USE IN STUDYING DIRECT CURRENT MAGNETIC MOTOR CONTROL IN ELECTRICAL-ELECTRONIC PROGRAMS. IT WAS DEVELOPED BY AN INSTRUCTIONAL MATERIALS SPECIALIST AND ADVISERS. EACH OF THE 15 ASSIGNMENT SHEETS PROVIDES THE LESSON SUBJECT, PURPOSE, INTRODUCTORY INFORMATION, STUDY REFERENCES, AND PROBLEMS. SOME OF THE LESSONS…

ELECTRICAL AND ELECTRONIC INDUSTRIAL CONTROL. A-C CONVENTIONAL MAGNETIC MOTOR CONTROL, PART I, UNIT 5, ASSIGNMENTS.

ERIC Educational Resources Information Center

SUTTON, MACK C.

THIS GUIDE IS FOR INDIVIDUAL STUDENT USE IN STUDYING ALTERNATING CURRENT CONVENTIONAL MAGNETIC MOTOR CONTROL IN ELECTRICAL-ELECTRONIC PROGRAMS. IT WAS DEVELOPED BY AN INSTRUCTIONAL MATERIALS SPECIALIST AND ADVISERS. EACH OF THE 10 ASSIGNMENT SHEETS PROVIDES THE LESSON SUBJECT, PURPOSE, INTRODUCTORY INFORMATION, STUDY REFERENCES, SUPPLEMENTARY…

BARBERING, A STUDY GUIDE AND PROGRESSION RECORD FOR BARBERING STUDENTS IN A COOPERATIVE TRAINING PROGRAM.

ERIC Educational Resources Information Center

Alabama Univ., University.

QUESTION-TYPE JOB OR ASSIGNMENT SHEETS IN THIS GUIDE DIRECT THE STUDENT'S RELATED STUDY IN COOPERATIVE TRAINING PROGRAMS. THE MATERIAL WAS DEVELOPED BY TRADE AND INDUSTRIAL COORDINATORS, SUBJECT MATTER SPECIALISTS, AND TEACHER EDUCATORS. IT WAS TESTED BY USE IN HIGH SCHOOL PROGRAMS. THE 61 JOB SHEETS ARE KEYED TO THREE RELATED REFERENCE BOOKS, BUT…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wemmer, D.E.; Kumar, N.V.; Metrione, R.M.

Toxin II from Radianthus paumotensis (Rp/sub II/) has been investigated by high-resolution NMR and chemical sequencing methods. Resonance assignments have been obtained for this protein by the sequential approach. NMR assignments could not be made consistent with the previously reported primary sequence for this protein, and chemical methods have been used to determine a sequence with which the NMR data are consistent. Analysis of the 2D NOE spectra shows that the protein secondary structure is comprised of two sequences of ..beta..-sheet, probably joined into a distorted continuous sheet, connected by turns and extended loops, without any regular ..cap alpha..-helical segments.more » The residues previously implicated in activity in this class of proteins, D8 and R13, occur in a loop region.« less

Automated Rapid Prototyping of 3D Ceramic Parts

NASA Technical Reports Server (NTRS)

McMillin, Scott G.; Griffin, Eugene A.; Griffin, Curtis W.; Coles, Peter W. H.; Engle, James D.

2005-01-01

An automated system of manufacturing equipment produces three-dimensional (3D) ceramic parts specified by computational models of the parts. The system implements an advanced, automated version of a generic rapid-prototyping process in which the fabrication of an object having a possibly complex 3D shape includes stacking of thin sheets, the outlines of which closely approximate the horizontal cross sections of the object at their respective heights. In this process, the thin sheets are made of a ceramic precursor material, and the stack is subsequently heated to transform it into a unitary ceramic object. In addition to the computer used to generate the computational model of the part to be fabricated, the equipment used in this process includes: 1) A commercially available laminated-object-manufacturing machine that was originally designed for building woodlike 3D objects from paper and was modified to accept sheets of ceramic precursor material, and 2) A machine designed specifically to feed single sheets of ceramic precursor material to the laminated-object-manufacturing machine. Like other rapid-prototyping processes that utilize stacking of thin sheets, this process begins with generation of the computational model of the part to be fabricated, followed by computational sectioning of the part into layers of predetermined thickness that collectively define the shape of the part. Information about each layer is transmitted to rapid-prototyping equipment, where the part is built layer by layer. What distinguishes this process from other rapid-prototyping processes that utilize stacking of thin sheets are the details of the machines and the actions that they perform. In this process, flexible sheets of ceramic precursor material (called "green" ceramic sheets) suitable for lamination are produced by tape casting. The binder used in the tape casting is specially formulated to enable lamination of layers with little or no applied heat or pressure. The tape is cut into individual sheets, which are stacked in the sheet-feeding machine until used. The sheet-feeding machine can hold enough sheets for about 8 hours of continuous operation.

AVAILABLE INSTRUCTIONAL MATERIALS.

ERIC Educational Resources Information Center

Indiana State Univ., Terre Haute.

THE INSTRUCTIONAL MATERIALS INCLUDE PROGRAM BROCHURES, CHARTS, COURSE OUTLINES, OVERHEAD TRANSPARENCIES, ASSIGNMENT SHEETS, STUDENT MANUALS, TEACHER MANUALS, TECHNICAL INFORMATION, AND RELATED INFORMATION IN VOCATIONAL EDUCATION. A BRIEF NOTE DESCRIBES EACH. (EM)

Developing effective assignment feedback for an interprofessional learning module-An action research project.

PubMed

Strudwick, Ruth; Day, Jane

2015-09-01

The first year interprofessional learning module at University Campus Suffolk (UCS) is delivered to 300 students and the students' assignments are marked by 20 members of staff from different health and social care professions. We were keen to find a way to reduce any inconsistencies and work with both staff and students to ensure that the essay and subsequent feedback were useful for all involved. The aims of the project were to evaluate the current marking process and feedback sheets used for year one inter-professional learning (IPL) marking, and to develop an appropriate marking tool and feedback sheet that would enable markers to provide more consistent feedback to the students. Participatory action research was used with both students and staff members being involved. Focus group and questions were used to ascertain views about the assignment feedback. The feedback from this action learning project helped us to enhance the feedback for students. There was also an increase in engagement with the assessment and feedback process amongst both staff and students. Copyright © 2015 Elsevier Ltd. All rights reserved.

General Metal Trades Book I. Units of Instruction. Teacher's Guide.

ERIC Educational Resources Information Center

East Texas State Univ., Commerce. Occupational Curriculum Lab.

This teacher's guide provides instructional materials for a 10-unit course in the General Metal Trades program. Each unit includes most or all of these basic components: performance objectives (unit and specific objectives), suggested teaching activities (a sheet outlining steps to follow to accomplish specific objectives), information sheets,…

Object memory effects on figure assignment: conscious object recognition is not necessary or sufficient.

PubMed

Peterson, M A; de Gelder, B; Rapcsak, S Z; Gerhardstein, P C; Bachoud-Lévi, A

2000-01-01

In three experiments we investigated whether conscious object recognition is necessary or sufficient for effects of object memories on figure assignment. In experiment 1, we examined a brain-damaged participant, AD, whose conscious object recognition is severely impaired. AD's responses about figure assignment do reveal effects from memories of object structure, indicating that conscious object recognition is not necessary for these effects, and identifying the figure-ground test employed here as a new implicit test of access to memories of object structure. In experiments 2 and 3, we tested a second brain-damaged participant, WG, for whom conscious object recognition was relatively spared. Nevertheless, effects from memories of object structure on figure assignment were not evident in WG's responses about figure assignment in experiment 2, indicating that conscious object recognition is not sufficient for effects of object memories on figure assignment. WG's performance sheds light on AD's performance, and has implications for the theoretical understanding of object memory effects on figure assignment.

3D 14N/1H Double Quantum/1H Single Quantum Correlation Solid-State NMR for Probing Parallel and Anti-Parallel Beta-Sheet Arrangement of Oligo-Peptides at Natural Abundance.

PubMed

Hong, You-Lee; Asakura, Tetsuo; Nishiyama, Yusuke

2018-05-08

β-sheet structure of oligo- and poly-peptides can be formed in anti-parallel (AP)- and parallel (P)-structure, which is the important feature to understand the structures. In principle, P- and AP-β-sheet structures can be identified by the presence (AP) and absence (P) of the interstrand 1HNH/1HNH correlations on a diagonal in 2D 1H double quantum (DQ)/1H single quantum (SQ) spectrum due to the different interstrand 1HNH/1HNH distances between these two arrangements. However, the 1HNH/1HNH peaks overlap to the 1HNH3+/1HNH3+ peaks, which always give cross peaks regardless of the β-sheet arrangement. The 1HNH3+/1HNH3+ peaks disturb the observation of the presence/absence of 1HNH/1HNH correlations and the assignment of 1HNH and 1HNH3+ is not always available. Here, 3D 14N/1H DQ/1H SQ correlation solid-state NMR experiments at fast magic angle spinning (70 kHz) are introduced to distinguish AP and P β-sheet structure. The 14N dimension allows the separate observation of 1HNH/1HNH peaks from 1HNH3+/1HNH3+ peaks with clear assignment of 1HNH and 1HNH3+. In addition, the high natural abundance of 1H and 14N enables 3D 14N/1H DQ/1H SQ experiments of oligo-alanines (Ala3-6) in four hours without any isotope labelling. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Single objective light-sheet microscopy for high-speed whole-cell 3D super-resolution

PubMed Central

Meddens, Marjolein B. M.; Liu, Sheng; Finnegan, Patrick S.; Edwards, Thayne L.; James, Conrad D.; Lidke, Keith A.

2016-01-01

We have developed a method for performing light-sheet microscopy with a single high numerical aperture lens by integrating reflective side walls into a microfluidic chip. These 45° side walls generate light-sheet illumination by reflecting a vertical light-sheet into the focal plane of the objective. Light-sheet illumination of cells loaded in the channels increases image quality in diffraction limited imaging via reduction of out-of-focus background light. Single molecule super-resolution is also improved by the decreased background resulting in better localization precision and decreased photo-bleaching, leading to more accepted localizations overall and higher quality images. Moreover, 2D and 3D single molecule super-resolution data can be acquired faster by taking advantage of the increased illumination intensities as compared to wide field, in the focused light-sheet. PMID:27375939

Wave-induced drift of large floating sheets

NASA Astrophysics Data System (ADS)

Christensen, K. H.; Weber, J. E.

In this article we study the wave-induced drift of large, flexible shallow floating objects, referred to as sheets. When surface waves propagate through a sheet, they provide a mean stress on the sheet, resulting in a mean drift. In response, the sheet generates an Ekman current. The drift velocity of the sheet is determined by (i) the wave-induced stress, (ii) the viscous stress due to the Ekman current, and (iii) the Coriolis force. The sheet velocity and the current beneath the sheet are determined for constant and depth-varying eddy viscosities.

Forced tearing of ductile and brittle thin sheets.

PubMed

Tallinen, T; Mahadevan, L

2011-12-09

Tearing a thin sheet by forcing a rigid object through it leads to complex crack morphologies; a single oscillatory crack arises when a tool is driven laterally through a brittle sheet, while two diverging cracks and a series of concertinalike folds forms when a tool is forced laterally through a ductile sheet. On the other hand, forcing an object perpendicularly through the sheet leads to radial petallike tears in both ductile and brittle materials. To understand these different regimes we use a combination of experiments, simulations, and simple theories. In particular, we describe the transition from brittle oscillatory tearing via a single crack to ductile concertina tearing with two tears by deriving laws that describe the crack paths and wavelength of the concertina folds and provide a simple phase diagram for the morphologies in terms of the material properties of the sheet and the relative size of the tool.

Single objective light-sheet microscopy for high-speed whole-cell 3D super-resolution

DOE PAGES

Meddens, Marjolein B. M.; Liu, Sheng; Finnegan, Patrick S.; ...

2016-01-01

Here, we have developed a method for performing light-sheet microscopy with a single high numerical aperture lens by integrating reflective side walls into a microfluidic chip. These 45° side walls generate light-sheet illumination by reflecting a vertical light-sheet into the focal plane of the objective. Light-sheet illumination of cells loaded in the channels increases image quality in diffraction limited imaging via reduction of out-of-focus background light. Single molecule super-resolution is also improved by the decreased background resulting in better localization precision and decreased photo-bleaching, leading to more accepted localizations overall and higher quality images. Moreover, 2D and 3D single moleculemore » super-resolution data can be acquired faster by taking advantage of the increased illumination intensities as compared to wide field, in the focused light-sheet.« less

Microwave. Instructor's Edition. Louisiana Vocational-Technical Education.

ERIC Educational Resources Information Center

Blanton, William

This publication contains related study assignments and job sheets for a course in microwave technology. The course is organized into 12 units covering the following topics: introduction to microwave, microwave systems, microwave oscillators, microwave modulators, microwave transmission lines, transmission lines, detectors and mixers, microwave…

Fuels planning: science synthesis and integration; social issues fact sheet 06: Important considerations for communicating about hazards

Treesearch

Rocky Mountain Research Station USDA Forest Service

2004-01-01

Effective public education and communication campaigns about wildland fire and fuels management should have clear objectives, and use the right techniques to achieve these objectives. This fact sheet lists seven important considerations for planning or implementing a hazard communication effort.

Topical Silicone Sheet Application in the Treatment of Hypertrophic Scars and Keloids.

PubMed

Westra, Iris; Pham, Hth; Niessen, Frank B

2016-10-01

Objective: Since the early 1980s, topical silicone sheets have been used in the treatment of hypertrophic scars and keloids.This study aimed to determine the optimal duration and application of these sheets. Design: multi-centered therapeutic study. Setting and participants: A total of 224 patients were included in this study; 205 patients with hypertrophic scars and 19 patients with keloids. Patients received treatment with a topical silicone sheet. Treated scars varied in age, ranging from two weeks to 62 years and treatment time ranged from one month to 16 months. Assessment of the scars was performed by the use of standardized study forms and digital photography. Measurements: Skin therapists objectively assessed the scars on its color, thickness, and elasticity. Patients themselves subjectively assessed their perception of their scar and their experience with the usage of the topical silicone sheet. Results: After applying the topical silicone sheet, all scars, regardless of type of scar and maturity, improved significantly in color, thickness, and elasticity. Conclusion: In this study, treatment with the topical silicone sheet showed significant improvement on both hypertrophic scars and keloids. Best results were reached when the silicone sheet was applied at least four hours per day.

Controllable curvature from planar polymer sheets in response to light.

PubMed

Hubbard, Amber M; Mailen, Russell W; Zikry, Mohammed A; Dickey, Michael D; Genzer, Jan

2017-03-22

The ability to change shape and control curvature in 3D structures starting from planar sheets can aid in assembly and add functionality to an object. Herein, we convert planar sheets of shape memory polymers (SMPs) into 3D objects with controllable curvature by dictating where the sheets shrink. Ink patterned on the surface of the sheet absorbs infrared (IR) light, resulting in localized heating, and the material shrinks locally wherever the temperature exceeds the activation temperature, T a . We introduce two different mechanisms for controlling curvature within SMP sheets. The 'direct' mechanism uses localized shrinkage to induce curvature only in regions patterned with ink. The 'indirect' mechanism uses localized shrinkage in regions patterned with ink to induce curvature in neighboring regions without ink through a balance of internal stresses. Finite element analysis predicts the final shape of the polymer sheets with excellent qualitative agreement with experimental studies. Results from this study show that curvature can be controlled by the distribution and darkness of the ink pattern on the polymer sheet. Additionally, we utilize the direct and indirect curvature mechanisms to demonstrate the formation and actuation of gripper devices, which represent the potential utility of this approach.

IDEAS.

ERIC Educational Resources Information Center

Young, Sharon L.

1991-01-01

Presented are four activities that focus on gathering and interpreting data about pizza as a basis for integrating mathematics, health, and social studies. Reproducible sheets for parents to use with their children, class-activity sheets, and a data sheet are provided. Each activity includes the objective, needed materials, directions, extensions,…

Large Ice Discharge From the Greenland Ice Sheet

NASA Technical Reports Server (NTRS)

Rignot, Eric

1999-01-01

The objectives of this work are to measure the ice discharge of the Greenland Ice Sheet close to the grounding line and/or calving front, and compare the results with mass accumulation and ablation in the interior to estimate the ice sheet mass balance.

Drafting. Competency Based Curriculum.

ERIC Educational Resources Information Center

Everly, Al; And Others

This competency based drafting curriculum is presented in seven specialization sections with units in each section containing a competency statement, performance objective, learning activities, evaluation, and quiz or problem sheets. Some units also contain answer sheets and/or handout sheets. Sections and number of units presented are (1) basic…

Are safety data sheets for cleaning products used in Norway a factor contributing to the risk of workers exposure to chemicals?

PubMed

Suleiman, Abdulqadir M; Svendsen, Kristin V H

2014-10-01

Cleaning products are considered less hazardous than those used in other sectors. Suppliers and distributors are less conscientious when it comes to informing users on health risks. The aim of the study was to elaborate on the usefulness and clarity of information in the safety data sheets (SDS) for cleaning products, and considering if the use of these SDSs can be seen as a risk factor towards occupational exposure to hazardous chemicals in the sector. Safety data sheets were selected based on the risk level of the product assigned in an industrial sector scheme. 320 SDSs for cleaning products were reviewed. Constituent components found in the products over a given threshold were listed and available information thereof used to assess the perceived non-hazard consideration of the chemicals. The contents of the SDSs was generic and mostly incomplete. Safety measures and health information lacked sufficient specificity despite varying compositions and concentrations of components. There is generally incompatibility between mentioned sections on the suggested non-hazardous nature of the products and health effects. Not all substances used in these products have harmonized classifications, which makes them open to various classification of the products and the suggested safety measures. This results in different companies classifying similar products differently. Risk management measures and suggested personal protective equipment (PPEs) are given haphazardly. Physical properties relevant to risk assessment are not included. The safety data sheets are ambiguous, and they lack relevant and important information. Inadequate information and risk assessment concerning the products can lead to workers being exposed to hazardous chemicals. Underestimation of the hazard contribution of the components of the products and the insufficient, non-objective mention of appropriate control and protective measures are the major contributing elements. There is a need to test the products in order to establish health effects and product specific safety measures.

Bio-sheet graft therapy for artificial gastric ulcer after endoscopic submucosal dissection: an animal feasibility study.

PubMed

Kwon, Chang-Il; Kim, Gwangil; Ko, Kwang Hyun; Jung, Yunho; Chung, Il-Kwun; Jeong, Seok; Lee, Don Haeng; Hong, Sung Pyo; Hahm, Ki Baik

2015-04-01

Various bio-sheet grafts have been attempted either to accelerate healing of artificial ulcers or to prevent adverse events after endoscopic submucosal dissection (ESD), but neither prospective nor mechanistic studies were available. To evaluate the substantial effect of a bio-sheet graft on artificial ulcer healing and its feasibility as an endoscopic treatment modality. Preclinical, in vivo animal experiment and proof-of-concept study. Animal laboratory. Three mini-pigs, Sus scrofa, mean age 14 months. Multiple ulcers sized 2.5 cm in diameter were generated by ESD in 3 mini-pigs and were assigned randomly into the following 3 groups; control group, bio-sheet group, or combination (bio-sheet plus drug) group. Bio-sheet grafts or bio-sheet plus drug combinations were applied on the artificial ulcers immediately after the ESD. Feasibility and efficacy of endoscopic bio-sheet graft therapy for the management of artificial ulcers and the evaluation of healing conditions based on histology changes in the remaining gastric bed tissues harvested from the stomachs. Thirty-three ESD specimens were obtained. On an image analysis of the ratio of healed area in the remaining gastric bed tissue compared with the matched dissected gastric mucosa, the control group showed the most significant improvement in healing activity among the 3 groups (P < .05), whereas the severity of inflammation in the remaining ulcer tissue was significantly attenuated in bio-sheet and combination groups (P < .05). Animal model. Although the bio-sheet grafts provided physical protection from gastric acid attack as reflected in the attenuated inflammation on the ulcer beds, unexpected delayed ulcer healing was noted in the bio-sheet graft group because of its physical hindrance of the healing process. Copyright © 2015 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.

33 CFR 331.6 - Filing an appeal.

Code of Federal Regulations, 2010 CFR

2010-07-01

... objections to the permit. The district engineer, upon evaluation of the applicant's objections, may: Modify... such modified permit to the applicant, enclosing an NAP fact sheet and an RFA form as well. Should the... an NAP fact sheet, RFA form, and a copy of the decision document for the project. If the district...

Validation of Welding Curriculum Manual.

ERIC Educational Resources Information Center

Stone, Sheila D.

A study was conducted to validate the welding curriculum materials developed and published by the Oklahoma State Department of Vocational and Technical Education. Twelve instructors collected achievement data (unit tests, assignment sheets, and evaluation forms) concerning the performance of 280 students on a total of 46 instructional units. Item…

Introduction to Natural Resources: Advanced Applications.

ERIC Educational Resources Information Center

Crummett, Dan

This guide, which is designed for use with student and teacher guides to a 10-unit secondary-level course in natural resources, contains a series of student supplements and advanced assignment and job sheets that provide students with additional opportunities to explore the following areas of natural resources and conservation education: outdoor…

Computer-Assisted Law Instruction: Clinical Education's Bionic Sibling

ERIC Educational Resources Information Center

Henn, Harry G.; Platt, Robert C.

1977-01-01

Computer-assisted instruction (CAI), like clinical education, has considerable potential for legal training. As an initial Cornell Law School experiment, a lesson in applying different corporate statutory dividend formulations, with a cross-section of balance sheets and other financial data, was used to supplement regular class assignments.…

Small Business Course for Older Americans. Student Handbook.

ERIC Educational Resources Information Center

American Association of Community and Junior Colleges, Washington, DC.

This student handbook was designed for a course which offers people aged 55 and older guidance in starting and operating a small business. Following introductory remarks concerning small businesses, information and assignment sheets related to each of the course's basic units are presented. Course units include the following: (1) Small Business…

SeaRISE: A Multidisciplinary Research Initiative to Predict Rapid Changes in Global Sea Level Caused by Collapse of Marine Ice Sheets

NASA Technical Reports Server (NTRS)

Bindschadler, Robert A. (Editor)

1990-01-01

The results of a workshop held to discuss the role of the polar ice sheets in global climate change are reported. The participants agreed that the most important aspect of the ice sheets' involvement in climate change is the potential of marine ice sheets to cause a rapid change in global sea level. To address this concern, a research initiative is called for that considers the full complexity of the coupled atmosphere-ocean-cryosphere-lithosphere system. This initiative, called SeaRISE (Sea-level Response to Ice Sheet Evolution) has the goal of predicting the contribution of marine ice sheets to rapid changes in global sea level in the next decade to few centuries. To attain this goal, a coordinated program of multidisciplinary investigations must be launched with the linked objectives of understanding the current state, internal dynamics, interactions, and history of this environmental system. The key questions needed to satisfy these objectives are presented and discussed along with a plan of action to make the SeaRISE project a reality.

Intraoperative use of a reflective blanket (Sirius rescue sheet) for temperature management in dogs less than 10 kg.

PubMed

Tünsmeyer, J; Bojarski, I; Nolte, I; Kramer, S

2009-07-01

To compare the effects of the Sirius rescue sheet with gel pads versus gel pads alone on intraoperative body temperature in dogs less than 10 kg. Forty small breed dogs undergoing elective surgical procedures were randomly assigned to two groups. One group was intraoperatively laid on warmed gel pads, and the other group was additionally wrapped in a Sirius rescue sheet. Oesophageal body temperature was determined every 10 minutes and compared between groups. Temperature of gel pads was measured preoperatively and postoperatively to compare heat loss of the gel pads between groups. The body temperature of dogs wrapped with the Sirius rescue sheet increased intraoperatively. In dogs just lying on warmed gel pads, a decrease in mean body temperature was revealed and mean body temperatures differed between groups after 40 minutes. Extent of heat loss from the gel pads did not differ between the groups. The Sirius rescue sheet, used in addition to warmed gel pads, led to higher intraoperative body temperatures in small breed dogs undergoing surgical procedures to the extremities and the head. The cost-effectiveness and ease of handling make this a useful addition to clinical practice.

LITE microscopy: Tilted light-sheet excitation of model organisms offers high resolution and low photobleaching

PubMed Central

Gerbich, Therese M.; Rana, Kishan; Suzuki, Aussie; Schaefer, Kristina N.; Heppert, Jennifer K.; Boothby, Thomas C.; Allbritton, Nancy L.; Gladfelter, Amy S.; Maddox, Amy S.

2018-01-01

Fluorescence microscopy is a powerful approach for studying subcellular dynamics at high spatiotemporal resolution; however, conventional fluorescence microscopy techniques are light-intensive and introduce unnecessary photodamage. Light-sheet fluorescence microscopy (LSFM) mitigates these problems by selectively illuminating the focal plane of the detection objective by using orthogonal excitation. Orthogonal excitation requires geometries that physically limit the detection objective numerical aperture (NA), thereby limiting both light-gathering efficiency (brightness) and native spatial resolution. We present a novel live-cell LSFM method, lateral interference tilted excitation (LITE), in which a tilted light sheet illuminates the detection objective focal plane without a sterically limiting illumination scheme. LITE is thus compatible with any detection objective, including oil immersion, without an upper NA limit. LITE combines the low photodamage of LSFM with high resolution, high brightness, and coverslip-based objectives. We demonstrate the utility of LITE for imaging animal, fungal, and plant model organisms over many hours at high spatiotemporal resolution. PMID:29490939

Measuring Discrimination in Education. NBER Working Paper No. 15057

ERIC Educational Resources Information Center

Hanna, Rema; Linden. Leigh

2009-01-01

In this paper, we illustrate a methodology to measure discrimination in educational contexts. In India, we ran an exam competition through which children compete for a large financial prize. We recruited teachers to grade the exams. We then randomly assigned child "characteristics" (age, gender, and caste) to the cover sheets of the…

The Effects of a Computerized Study Program on the Acquisition of Science Vocabulary

ERIC Educational Resources Information Center

Rollins, Karen F.

2012-01-01

The following study examined the difference in science vocabulary acquisition comparing computer-assisted learning and a traditional study review sheet. Fourth and fifth grade students from a suburban school in central Texas were randomly selected and randomly assigned to either experimental group or control group. Both groups were given a…

40 CFR 370.42 - What is Tier II inventory information?

Code of Federal Regulations, 2013 CFR

2013-07-01

... common name of the chemical as provided on the Material Safety Data Sheet and its Chemical Abstract....64(a). (2) Indicate whether the chemical is: pure or mixture; solid, liquid, or gas; and whether the... Inventory (TRI) and Risk Management Program. If your facility has not been assigned an identification number...

Exploring Norms and Moral Authority through Content Analysis of Classic Texts.

ERIC Educational Resources Information Center

Wallace, Richard Cheever

1993-01-01

Describes a class assignment for a college-level sociology course in which students read from religious texts to identify norms and sanctions. Reports that students expressed positive comments about the activity. Includes suggestions for preparing materials, instructions for implementing the activity, and a coding sheet to be used by students.…

Area Reports. Advanced materials and devices research area. Silicon materials research task, and advanced silicon sheet task

NASA Technical Reports Server (NTRS)

1986-01-01

The objectives of the Silicon Materials Task and the Advanced Silicon Sheet Task are to identify the critical technical barriers to low-cost silicon purification and sheet growth that must be overcome to produce a PV cell substrate material at a price consistent with Flat-plate Solar Array (FSA) Project objectives and to overcome these barriers by performing and supporting appropriate R&D. Progress reports are given on silicon refinement using silane, a chemical vapor transport process for purifying metallurgical grade silicon, silicon particle growth research, and modeling of silane pyrolysis in fluidized-bed reactors.

Incorporation of ice sheet models into an Earth system model: Focus on methodology of coupling

NASA Astrophysics Data System (ADS)

Rybak, Oleg; Volodin, Evgeny; Morozova, Polina; Nevecherja, Artiom

2018-03-01

Elaboration of a modern Earth system model (ESM) requires incorporation of ice sheet dynamics. Coupling of an ice sheet model (ICM) to an AOGCM is complicated by essential differences in spatial and temporal scales of cryospheric, atmospheric and oceanic components. To overcome this difficulty, we apply two different approaches for the incorporation of ice sheets into an ESM. Coupling of the Antarctic ice sheet model (AISM) to the AOGCM is accomplished via using procedures of resampling, interpolation and assigning to the AISM grid points annually averaged meanings of air surface temperature and precipitation fields generated by the AOGCM. Surface melting, which takes place mainly on the margins of the Antarctic peninsula and on ice shelves fringing the continent, is currently ignored. AISM returns anomalies of surface topography back to the AOGCM. To couple the Greenland ice sheet model (GrISM) to the AOGCM, we use a simple buffer energy- and water-balance model (EWBM-G) to account for orographically-driven precipitation and other sub-grid AOGCM-generated quantities. The output of the EWBM-G consists of surface mass balance and air surface temperature to force the GrISM, and freshwater run-off to force thermohaline circulation in the oceanic block of the AOGCM. Because of a rather complex coupling procedure of GrIS compared to AIS, the paper mostly focuses on Greenland.

Flat-plate solar array project. Volume 3: Silicon sheet: Wafers and ribbons

NASA Technical Reports Server (NTRS)

Briglio, A.; Dumas, K.; Leipold, M.; Morrison, A.

1986-01-01

The primary objective of the Silicon Sheet Task of the Flat-Plate Solar Array (FSA) Project was the development of one or more low cost technologies for producing silicon sheet suitable for processing into cost-competitive solar cells. Silicon sheet refers to high purity crystalline silicon of size and thickness for fabrication into solar cells. Areas covered in the project were ingot growth and casting, wafering, ribbon growth, and other sheet technologies. The task made and fostered significant improvements in silicon sheet including processing of both ingot and ribbon technologies. An additional important outcome was the vastly improved understanding of the characteristics associated with high quality sheet, and the control of the parameters required for higher efficiency solar cells. Although significant sheet cost reductions were made, the technology advancements required to meet the task cost goals were not achieved.

Low cost light-sheet microscopy for whole brain imaging

NASA Astrophysics Data System (ADS)

Kumar, Manish; Nasenbeny, Jordan; Kozorovitskiy, Yevgenia

2018-02-01

Light-sheet microscopy has evolved as an indispensable tool in imaging biological samples. It can image 3D samples at fast speed, with high-resolution optical sectioning, and with reduced photobleaching effects. These properties make light-sheet microscopy ideal for imaging fluorophores in a variety of biological samples and organisms, e.g. zebrafish, drosophila, cleared mouse brains, etc. While most commercial turnkey light-sheet systems are expensive, the existing lower cost implementations, e.g. OpenSPIM, are focused on achieving high-resolution imaging of small samples or organisms like zebrafish. In this work, we substantially reduce the cost of light-sheet microscope system while targeting to image much larger samples, i.e. cleared mouse brains, at single-cell resolution. The expensive components of a lightsheet system - excitation laser, water-immersion objectives, and translation stage - are replaced with an incoherent laser diode, dry objectives, and a custom-built Arduino-controlled translation stage. A low-cost CUBIC protocol is used to clear fixed mouse brain samples. The open-source platforms of μManager and Fiji support image acquisition, processing, and visualization. Our system can easily be extended to multi-color light-sheet microscopy.

Issues in subsurface exploration of ice sheets

NASA Technical Reports Server (NTRS)

French, L.; Carsey, F.; Zimmerman, W.

2000-01-01

Exploration of the deep subsurface ice sheets of Earth, Mars, Europa, and Titan has become a major consideration in addressing scientific objectives in climate change, extremophile biology, exobiology,chemical weathering, planetary evolution and ice dynamics.

A New Secondary Structure Assignment Algorithm Using Cα Backbone Fragments

PubMed Central

Cao, Chen; Wang, Guishen; Liu, An; Xu, Shutan; Wang, Lincong; Zou, Shuxue

2016-01-01

The assignment of secondary structure elements in proteins is a key step in the analysis of their structures and functions. We have developed an algorithm, SACF (secondary structure assignment based on Cα fragments), for secondary structure element (SSE) assignment based on the alignment of Cα backbone fragments with central poses derived by clustering known SSE fragments. The assignment algorithm consists of three steps: First, the outlier fragments on known SSEs are detected. Next, the remaining fragments are clustered to obtain the central fragments for each cluster. Finally, the central fragments are used as a template to make assignments. Following a large-scale comparison of 11 secondary structure assignment methods, SACF, KAKSI and PROSS are found to have similar agreement with DSSP, while PCASSO agrees with DSSP best. SACF and PCASSO show preference to reducing residues in N and C cap regions, whereas KAKSI, P-SEA and SEGNO tend to add residues to the terminals when DSSP assignment is taken as standard. Moreover, our algorithm is able to assign subtle helices (310-helix, π-helix and left-handed helix) and make uniform assignments, as well as to detect rare SSEs in β-sheets or long helices as outlier fragments from other programs. The structural uniformity should be useful for protein structure classification and prediction, while outlier fragments underlie the structure–function relationship. PMID:26978354

Validation and Design of Sheet Retrofits

DTIC Science & Technology

2010-10-31

enough to allow for rotation of the top of the wall without development of an axial force. Obviously, these walls are not load bearing . This type...structures are commonly constructed using CMU blocks to infill non- load bearing walls (Hammons, 1999). Many of these structures were built in a... axial loads within the sheet. 3 Figure 1. Infill Masonry Wall Retrofit Concept 2.1. Objective The objective of the research documented in

Improved Production Of Wrought Articles From Powders

NASA Technical Reports Server (NTRS)

Thomas, James R.; Singleton, Ogle R.

1994-01-01

Improved technique for consolidation of powders into dense articles developed. Peripheral bands used in consolidation, forging, and rolling operations. Facilitates consolidation of dispersion-hardened aluminous powders and composite mixtures for processing to such useful wrought articles as plates and sheets. Potential use in production of plates and sheets and perhaps other objects from "hard" powders, particularly from powders, objects made from which have propensity to crack when mechanically worked to other forms.

High-speed volume measurement system

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lane, Michael H.; Doyle, Jr., James L.; Brinkman, Michael J.

2018-01-30

Disclosed is a volume sensor having a first axis, a second axis, and a third axis, each axis including a laser source configured to emit a beam; a parallel beam generating assembly configured to receive the beam and split the beam into a first parallel beam and a second parallel beam, a beam-collimating assembly configured to receive the first parallel beam and the second parallel beam and output a first beam sheet and a second beam sheet, the first beam sheet and the second beam sheet being configured to traverse the object aperture; a first collecting lens and a secondmore » collecting lens; and a first photodetector and a second photodetector, the first photodetector and the second photodetector configured to output an electrical signal proportional to the object; wherein the first axis, the second axis, and the third axis are arranged at an angular offset with respect to each other.« less

Ice sheet radar altimetry

NASA Technical Reports Server (NTRS)

Zwally, J.

1988-01-01

The surface topography of the Greenland and Antarctic ice sheets between 72 degrees north and south was mapped using radar altimetry data from the U.S. Navy GEOSAT. The glaciological objectives of this activity were to study the dynamics of the ice flow, changes in the position of floating ice-shelf fronts, and ultimately to measure temporal changes in ice surface elevation indicative of ice sheet mass balance.

Valuing Exercises for the Middle School. Resource Monograph No. 11.

ERIC Educational Resources Information Center

Casteel, J. Doyle; And Others

One of the major goals of the middle school is to help students gain and refine skills in the area of values clarification. One way of securing such value clarification is to plan and assign value sheets--carefully planned and written activities designed to elicit value clarification patterns of language usage from students. Six different formats…

Military Curriculum Materials for Vocational and Technical Education. Fundamentals of Electricity, 3-7.

ERIC Educational Resources Information Center

Ohio State Univ., Columbus. National Center for Research in Vocational Education.

This self-paced correspondence course for independent study in electricity was adapted from military curriculum materials for use in vocational education. This basic course is designed to provide the student with some fundamentals of electricity--not with specific job skills. The seven lessons of the course each have a lesson assignment sheet with…

On the problem of resonance assignments in solid state NMR of uniformly 15N, 13C-labeled proteins

NASA Astrophysics Data System (ADS)

Tycko, Robert

2015-04-01

Determination of accurate resonance assignments from multidimensional chemical shift correlation spectra is one of the major problems in biomolecular solid state NMR, particularly for relative large proteins with less-than-ideal NMR linewidths. This article investigates the difficulty of resonance assignment, using a computational Monte Carlo/simulated annealing (MCSA) algorithm to search for assignments from artificial three-dimensional spectra that are constructed from the reported isotropic 15N and 13C chemical shifts of two proteins whose structures have been determined by solution NMR methods. The results demonstrate how assignment simulations can provide new insights into factors that affect the assignment process, which can then help guide the design of experimental strategies. Specifically, simulations are performed for the catalytic domain of SrtC (147 residues, primarily β-sheet secondary structure) and the N-terminal domain of MLKL (166 residues, primarily α-helical secondary structure). Assuming unambiguous residue-type assignments and four ideal three-dimensional data sets (NCACX, NCOCX, CONCA, and CANCA), uncertainties in chemical shifts must be less than 0.4 ppm for assignments for SrtC to be unique, and less than 0.2 ppm for MLKL. Eliminating CANCA data has no significant effect, but additionally eliminating CONCA data leads to more stringent requirements for chemical shift precision. Introducing moderate ambiguities in residue-type assignments does not have a significant effect.

Learning in depth with the bespoke rubric-supported online poster presentation

NASA Astrophysics Data System (ADS)

Lajevardipour, Alireza; Wood, Andrew

2017-08-01

In our course of Biomedical Imaging, we introduced a research project as an assignment that included an online poster presentation. To assess the assignment, an adjusted criteria sheet was created, where it facilitated providing students with an effective feedback linked to particular criteria. Students are expected to produce a scientific poster to present the result of their investigation and upload it to an online discussion board. In addition, they are required to read their colleagues' works and provide peer-feedback by asking quality questions about principles and results, also on-line. Subtle distribution of marks in the rubric balances focus between preparing poster and providing peer-feedbacks.

Text block identification in restoration process of Javanese script damage

NASA Astrophysics Data System (ADS)

Himamunanto, A. R.; Setyowati, E.

2018-05-01

Generally, in a sheet of documents there are two objects of information, namely text and image. A text block area in the sheet of manuscript is a vital object because the restoration process would be done only in this object. Text block or text area identification becomes an important step before. This paper describes the steps leading to the restoration of Java script destruction. The process stages are: pre-processing, identification of text block, segmentation, damage identification, restoration. The test result based on the input manuscript “Hamong Tani” show that the system works with a success rate of 82.07%

Strain and mechanical properties of the VCM multilayer sheet and their composites using the digital speckle correlation method.

PubMed

Zhang, Dehai; Xie, Guizhong; Li, Yanqin; Liu, Jianxiu

2015-09-01

The digital speckle correlation method (DSCM) is introduced to solve the challenging problems in the related geometric measurement. Theoretical calculations of strain are deduced using the DSCM. Corresponding strains along x and y directions are obtained from uniaxial tension experiments and digital speckle measurements, using the VCM nondeep drawing multilayer sheet, the VCM deep-drawing multilayer sheet, clad films, nondeep drawing substrate, and deep-drawing substrate sheet as the targeted experimental objects. The results show that the maximum strains along the x direction of the VCM nondeep drawing multilayer sheet, the VCM deep-drawing multilayer sheet, clad film, nondeep drawing substrate, and deep-drawing substrate sheet are 68.473%, 48.632%, 91.632%, 50.784% and 40.068%, respectively, while the maximum strains along the y direction are -2.657%, -15.381%, 2.826%, -9.780% and -7.783%, respectively. The mechanical properties of the VCM multilayer sheet are between those of the substrate and clad film, while mechanical properties of the VCM deep-drawing multilayer sheet are superior to those of the VCM nondeep drawing multi-layer sheet.

Color inference in visual communication: the meaning of colors in recycling.

PubMed

Schloss, Karen B; Lessard, Laurent; Walmsley, Charlotte S; Foley, Kathleen

2018-01-01

People interpret abstract meanings from colors, which makes color a useful perceptual feature for visual communication. This process is complicated, however, because there is seldom a one-to-one correspondence between colors and meanings. One color can be associated with many different concepts (one-to-many mapping) and many colors can be associated with the same concept (many-to-one mapping). We propose that to interpret color-coding systems, people perform assignment inference to determine how colors map onto concepts. We studied assignment inference in the domain of recycling. Participants saw images of colored but unlabeled bins and were asked to indicate which bins they would use to discard different kinds of recyclables and trash. In Experiment 1, we tested two hypotheses for how people perform assignment inference. The local assignment hypothesis predicts that people simply match objects with their most strongly associated color. The global assignment hypothesis predicts that people also account for the association strengths between all other objects and colors within the scope of the color-coding system. Participants discarded objects in bins that optimized the color-object associations of the entire set, which is consistent with the global assignment hypothesis. This sometimes resulted in discarding objects in bins whose colors were weakly associated with the object, even when there was a stronger associated option available. In Experiment 2, we tested different methods for encoding color-coding systems and found that people were better at assignment inference when color sets simultaneously maximized the association strength between assigned color-object parings while minimizing associations between unassigned pairings. Our study provides an approach for designing intuitive color-coding systems that facilitate communication through visual media such as graphs, maps, signs, and artifacts.

The First Annual West Antarctic Ice Sheet (WAIS) Science Workshop

NASA Technical Reports Server (NTRS)

Bindschadler, Robert A. (Editor)

1993-01-01

A compilation of abstracts presented at the workshop are presented. The goal was to answer the question, what is the future behavior and potential for rapid collapse of the West Antarctic Ice Sheet (WAIS)? The workshop was organized into four sessions corresponding to the four objectives identified as necessary to reach the WAIS workshop goal: history, current behavior, internal dynamics, and environmental interactions. Presentations were organized by their relevance to each objective, rather than by discipline.

Sequence-specific sup 1 H NMR resonance assignments of Bacillus subtilis HPr: Use of spectra obtained from mutants to resolve spectral overlap

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wittekind, M.; Klevit, R.E.; Reizer, J.

1990-08-07

On the basis of an analysis of two-dimensional {sup 1}H NMR spectra, the complete sequence-specific {sup 1}H NMR assignments are presented for the phosphocarrier protein HPr from the Gram-positive bacterium Bacillus subtilis. During the assignment procedure, extensive use was made of spectra obtained from point mutants of HPr in order to resolve spectral overlap and to provide verification of assignments. Regions of regular secondary structure were identified by characteristic patterns of sequential backbone proton NOEs and slowly exchanging amide protons. B subtilis HPr contains four {beta}-strands that form a single antiparallel {beta}-sheet and two well-defined {alpha}-helices. There are two stretchesmore » of extended backbone structure, one of which contains the active site His{sub 15}. The overall fold of the protein is very similar to that of Escherichia coli HPr determined by NMR studies.« less

Flat-plate solar array project. Volume 4: High-efficiency solar cells

NASA Technical Reports Server (NTRS)

Leipold, M.; Cheng, L.; Daud, T.; Mokashi, A.; Burger, D.; Christensen, E. (Editor); Murry, J. (Editor); Bengelsdorf, I. (Editor)

1986-01-01

The High Efficiency Solar Cell Task was assigned the objective of understanding and developing high efficiency solar cell devices that would meet the cost and performance goals of the Flat Plate Solar Array (FSA) Project. The need for research dealing with high efficiency devices was considered important because of the role efficiency plays in reducing price per watt of generated energy. The R&D efforts conducted during the 1982 to 1986 period are summarized to provide understanding and control of energy conversion losses associated with crystalline silicon solar cells. New levels of conversion efficiency were demonstrated. Major contributions were made both to the understanding and reduction of bulk and surface losses in solar cells. For example, oxides, nitrides, and polysilicon were all shown to be potentially useful surface passivants. Improvements in measurement techniques were made and Auger coefficients and spectral absorption data were obtained for unique types of silicon sheets. New modelling software was developed including a program to optimize a device design based on input characteristics of a cell.

Recent progress in terrestrial photovoltaic collector technology

NASA Technical Reports Server (NTRS)

Ferber, R. R.

1982-01-01

The U.S. Photovoltaic Research and Development Program has the objective to develop the technology necessary to foster widespread grid-competitive electric power generation by the late 1980s. The flat-plate and the concentrator collector activities form the nucleus of the program. The project is concerned with the refining of silicon, silicon sheet production, solar cell processing and fabrication, encapsulation materials development, and collector design and production. The Large-Area Silicon Sheet Task has the objective to develop and demonstrate the feasibility of several methods for producing large area silicon sheet material suitable for fabricating low-cost, high-efficiency solar cells. It is expected that a variety of economic flat-plate and concentrator collectors will become commercially available for grid-connected applications.

Effects of flow sheet implementation on physician performance in the management of asthmatic patients.

PubMed

Ruoff, Gary

2002-01-01

This project focused on increasing compliance, in a large family practice group, with quality indicators for the management of asthma. The objective was to determine if use of a flow sheet incorporating the Global Initiative for Asthma (GINA) guidelines could improve compliance with those guidelines if the flow sheet was placed in patients' medical records. After review and selection of 14 clinical quality indicators, physicians in the practice implemented a flow sheet as an intervention. These flow sheets were inserted into the records of 122 randomly selected patients with asthma. Medical records were reviewed before the flow sheets were placed in the records, and again approximately 6 months later, to determine if there was a change in compliance with the quality indicators. Improvement of documentation was demonstrated in 13 of the 14 quality indicators. The results indicate that compliance with asthma management quality indicators can improve with the use of a flow sheet.

Technology Systems. Laboratory Activities.

ERIC Educational Resources Information Center

Brame, Ray; And Others

This guide contains 43 modules of laboratory activities for technology education courses. Each module includes an instructor's resource sheet and the student laboratory activity. Instructor's resource sheets include some or all of the following elements: module number, course title, activity topic, estimated time, essential elements, objectives,…

Prevention of postsurgical scars: comparsion of efficacy and convenience between silicone gel sheet and topical silicone gel.

PubMed

Kim, Sue-Min; Choi, Jung-Sik; Lee, Jung-Ho; Kim, Young-Jin; Jun, Young-Joon

2014-11-01

To date, few studies have compared the effectiveness of topical silicone gels versus that of silicone gel sheets in preventing scars. In this prospective study, we compared the efficacy and the convenience of use of the 2 products. We enrolled 30 patients who had undergone a surgical procedure 2 weeks to 3 months before joining the study. These participants were randomly assigned to 2 treatment arms: one for treatment with a silicone gel sheet, and the other for treatment with a topical silicone gel. Vancouver Scar Scale (VSS) scores were obtained for all patients; in addition, participants completed scoring patient questionnaires 1 and 3 months after treatment onset. Our results reveal not only that no significant difference in efficacy exists between the 2 products but also that topical silicone gels are more convenient to use. While previous studies have advocated for silicone gel sheets as first-line therapies in postoperative scar management, we maintain that similar effects can be expected with topical silicone gel. The authors recommend that, when clinicians have a choice of silicone-based products for scar prevention, they should focus on each patient's scar location, lifestyle, and willingness to undergo scar prevention treatment.

The Efficacy of a Silicone Sheet in Postoperative Scar Management.

PubMed

Kim, Jin Sam; Hong, Joon Pio; Choi, Jong Woo; Seo, Dong Kyo; Lee, Eun Sook; Lee, Ho Seong

2016-09-01

Silicone gel sheeting has been introduced to prevent scarring, but objective evidence for its usefulness in scar healing is limited. Therefore, the authors' objective was to examine the effectiveness of silicone gel sheeting by randomly applying it to only unilateral scars from a bilateral hallux valgus surgery with symmetrical closure. In a prospective randomized, blinded, intraindividual comparison study, the silicone gel sheeting was applied to 1 foot of a hallux valgus incision scar (an experiment group) for 12 weeks upon removal of the stitches, whereas the symmetrical scar from the other foot was left untreated (a control group). The scars were evaluated at 4 and 12 weeks after the silicon sheet application. The Vancouver Scar Scale was used to measure the vascularity, pigmentation, pliability, height, and length of the scars. Adverse effects were also evaluated, and they included pain, itchiness, rash, erythema, and skin softening. At weeks 4 and 12, the experiment group scored significantly better on the Vancouver Scar Scale in all items, except length (P < .05 for all except the length of scar), compared with the control group. In all items, adverse effects of the experiment group were significantly lower than those of the control group at week 12, suggesting that direct attachment of the silicone sheet does not cause adverse effects (P < .05). To the authors' knowledge, this is one of the first models to minimize bias related to scar evaluation by using symmetrical scars. The early silicone sheet application did show a significant improvement in prevention of postoperative scarring.

Vacuum forming of thermoplastic sheet results in low-cost investment casting patterns

NASA Technical Reports Server (NTRS)

Clarke, A. E., Jr.

1964-01-01

Vacuum forming of a sheet of thermoplastic material around a mandrel conforming to the shape of the finished object provides a pattern for an investment mold. The thickness of the metal part is determined by the thickness of the plastic pattern.

Facts About Drug Abuse: Trainer's Manual.

ERIC Educational Resources Information Center

Link, William E.; And Others

Following an introductory survey of the course, this modular drug abuse trainer's manual contains all course-specified materials. These materials are: the course goals and objectives; time/activity sheets; trainer guidelines, process notes, and exercise instructions; detailed lectures and supplementary information. The time/activity sheets contain…

International Energy Agency (IEA): Implementing Agreement for Co-operation in the Research and Development of Wind Turbine Systems (IEA Wind)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sinclair, Karin C

This fact sheet covers the work that is being done via the International Energy Agency Task 34 (WREN). The fact sheet highlights the objective, strategy, primary activities, members, and contacts for this task.

Permission Form Synopses to Improve Parents' Understanding of Research: A Randomized Trial

PubMed Central

D'Angio, Carl T.; Wang, Hongyue; Hunn, Julianne E.; Pryhuber, Gloria S.; Chess, Patricia R.; Lakshminrusimha, Satyan

2017-01-01

Objective We hypothesized that, among parents of potential neonatal research subjects, an accompanying cover sheet added to the permission form (intervention) would increase understanding of the research, when compared to a standard form (control). Study Design This pilot study enrolled parents approached for one of two index studies: one randomized trial and one observational study. A one-page cover sheet described critical study information. Families were randomized 1:1 to receive the cover sheet or not. Objective and subjective understanding and satisfaction were measured. Result Thirty-two parents completed all measures (17 control, 15 intervention). There were no differences in comprehension score (16.8 ± 5.7 v. 16.3 ± 3.5), subjective understanding (median 6.0 v. 6.5), or overall satisfaction with consent (median 7.0 v. 6.5) between control and intervention groups (all p>0.50). Conclusion A simplified permission form cover sheet had no effect on parents' understanding of studies for which their newborns were being recruited. PMID:28358380

Strike Up the Score: Deriving Searchable and Playable Digital Formats from Sheet Music; Smart Objects and Open Archives; Building the Archives of the Future: Advanced in Preserving Electronic Records at the National Archives and Records Administration; From the Digitized to the Digital Library.

ERIC Educational Resources Information Center

Choudhury, G. Sayeed; DiLauro, Tim; Droettboom, Michael; Fujinaga, Ichiro; MacMillan, Karl; Nelson, Michael L.; Maly, Kurt; Thibodeau, Kenneth; Thaller, Manfred

2001-01-01

These articles describe the experiences of the Johns Hopkins University library in digitizing their collection of sheet music; motivation for buckets, Smart Object, Dumb Archive (SODA) and the Open Archives Initiative (OAI), and initial experiences using them in digital library (DL) testbeds; requirements for archival institutions, the National…

Further exploration of the conformational space of α-synuclein fibrils: solid-state NMR assignment of a high-pH polymorph.

PubMed

Verasdonck, Joeri; Bousset, Luc; Gath, Julia; Melki, Ronald; Böckmann, Anja; Meier, Beat H

2016-04-01

Polymorphism is a common and important phenomenon for protein fibrils which has been linked to the appearance of strains in prion and other neurodegenerative diseases. Parkinson disease is a frequently occurring neurodegenerative pathology, tightly associated with the formation of Lewy bodies. These deposits mainly consist of α-synuclein in fibrillar, β-sheet-rich form. α-synuclein is known to form numerous different polymorphs, which show distinct structural features. Here, we describe the chemical shift assignments, and derive the secondary structure, of a polymorph that was fibrillized at higher-than-physiological pH conditions. The fibrillar core contains residues 40-95, with both the C- and N-terminus not showing any ordered, rigid parts. The chemical shifts are similar to those recorded previously for an assigned polymorph that was fibrillized at neutral pH.

Drilling Machines: Vocational Machine Shop.

ERIC Educational Resources Information Center

Thomas, John C.

The lessons and supportive information in this field tested instructional block provide a guide for teachers in developing a machine shop course of study in drilling. The document is comprised of operation sheets, information sheets, and transparency masters for 23 lessons. Each lesson plan includes a performance objective, material and tools,…

14 CFR Section 14 - Objective Classification-Nonoperating Income and Expense

Code of Federal Regulations, 2010 CFR

2010-01-01

.... [ER-1401, 50 FR 245, Jan. 3, 1985] 81Interest on Long-term Debt and Capital Leases. (a) Record here... sheet classification purposes. 81.2Interest expense—capital leases. Record here for all capitalized... reasonably identifiable. (c) Amortization expense attributable to capital leases recorded in balance sheet...

Math for Masons. (Revised).

ERIC Educational Resources Information Center

Heppa, Victor

This student manual is concerned with the practical application of mathematics as used by masons. The manual's design allows students to work at their own pace. Included in each of the five units are individual lesson sheets with written instructions and explanations. Each information sheet states that topic's objectives, information about the…

Medical-Surgical II. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This publication is designed to provide students with the knowledge they need to pursue a career in medical-surgical nursing. Fifteen units are provided. Each instructional unit includes some or all of the basic components of a unit of instruction: performance objectives, suggested activities for the teacher, information sheets, job sheets,…

Machine Shop Practice. Trade and Industrial Education Course of Study.

ERIC Educational Resources Information Center

Emerly, Robert J.; And Others

Designed for secondary school students who are interested in becoming machinists, this beginning course guide in machine shop practice is organized into the following sections: (1) Introduction, (2) instructional plan, (3) educational philosophy, (4) specific course objectives, (5) course outline, (6) job sheets, and (7) operation sheets. The…

14 CFR Section 14 - Objective Classification-Nonoperating Income and Expense

Code of Federal Regulations, 2011 CFR

2011-01-01

.... [ER-1401, 50 FR 245, Jan. 3, 1985] 81Interest on Long-term Debt and Capital Leases. (a) Record here... sheet classification purposes. 81.2Interest expense—capital leases. Record here for all capitalized... reasonably identifiable. (c) Amortization expense attributable to capital leases recorded in balance sheet...

Medical-Surgical I. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This publication is designed to provide students with the knowledge they need to pursue a career in medical-surgical nursing. Eight units are provided. Each instructional unit includes some or all of the basic components of a unit of instruction: performance objectives, suggested activities for the teacher, information sheets, job sheets, written…

Laboratory and field measurements and evaluations of vibration at the handles of riveting hammers

PubMed Central

McDOWELL, THOMAS W.; WARREN, CHRISTOPHER; WELCOME, DANIEL E.; DONG, REN G.

2015-01-01

The use of riveting hammers can expose workers to harmful levels of hand-transmitted vibration (HTV). As a part of efforts to reduce HTV exposures through tool selection, the primary objective of this study was to evaluate the applicability of a standardized laboratory-based riveting hammer assessment protocol for screening riveting hammers. The second objective was to characterize the vibration emissions of reduced vibration riveting hammers and to make approximations of the HTV exposures of workers operating these tools in actual work tasks. Eight pneumatic riveting hammers were selected for the study. They were first assessed in a laboratory using the standardized method for measuring vibration emissions at the tool handle. The tools were then further assessed under actual working conditions during three aircraft sheet metal riveting tasks. Although the average vibration magnitudes of the riveting hammers measured in the laboratory test were considerably different from those measured in the field study, the rank orders of the tools determined via these tests were fairly consistent, especially for the lower vibration tools. This study identified four tools that consistently exhibited lower frequency-weighted and unweighted accelerations in both the laboratory and workplace evaluations. These observations suggest that the standardized riveting hammer test is acceptable for identifying tools that could be expected to exhibit lower vibrations in workplace environments. However, the large differences between the accelerations measured in the laboratory and field suggest that the standardized laboratory-based tool assessment is not suitable for estimating workplace riveting hammer HTV exposures. Based on the frequency-weighted accelerations measured at the tool handles during the three work tasks, the sheet metal mechanics assigned to these tasks at the studied workplace are unlikely to exceed the daily vibration exposure action value (2.5 m s−2) using any of the evaluated riveting hammers. PMID:22539561

Magnetic Modeling of a Rotating Flux Concentrator System Designed to Mitigate Noise in Large Magnetic Sensors

DTIC Science & Technology

2010-09-01

region were defined as a background. The flux concentrators were drawn as solid pieces and assigned the material properties of permalloy ( NiFe ), with...assigning properties (coercivity, permeability, etc.) to the objects, assigning boundaries or sources, seeding the objects and creating a mesh, and then...a permeability of 5000 as that is a value readily achieved in this material. The material properties assigned to this background are those of a

Assessing the formability of metallic sheets by means of localized and diffuse necking models

NASA Astrophysics Data System (ADS)

Comşa, Dan-Sorin; Lǎzǎrescu, Lucian; Banabic, Dorel

2016-10-01

The main objective of the paper consists in elaborating a unified framework that allows the theoretical assessment of sheet metal formability. Hill's localized necking model and the Extended Maximum Force Criterion proposed by Mattiasson, Sigvant, and Larsson have been selected for this purpose. Both models are thoroughly described together with their solution procedures. A comparison of the theoretical predictions with experimental data referring to the formability of a DP600 steel sheet is also presented by the authors.

An object-oriented, coprocessor-accelerated model for ice sheet simulations

NASA Astrophysics Data System (ADS)

Seddik, H.; Greve, R.

2013-12-01

Recently, numerous models capable of modeling the thermo-dynamics of ice sheets have been developed within the ice sheet modeling community. Their capabilities have been characterized by a wide range of features with different numerical methods (finite difference or finite element), different implementations of the ice flow mechanics (shallow-ice, higher-order, full Stokes) and different treatments for the basal and coastal areas (basal hydrology, basal sliding, ice shelves). Shallow-ice models (SICOPOLIS, IcIES, PISM, etc) have been widely used for modeling whole ice sheets (Greenland and Antarctica) due to the relatively low computational cost of the shallow-ice approximation but higher order (ISSM, AIF) and full Stokes (Elmer/Ice) models have been recently used to model the Greenland ice sheet. The advance in processor speed and the decrease in cost for accessing large amount of memory and storage have undoubtedly been the driving force in the commoditization of models with higher capabilities, and the popularity of Elmer/Ice (http://elmerice.elmerfem.com) with an active user base is a notable representation of this trend. Elmer/Ice is a full Stokes model built on top of the multi-physics package Elmer (http://www.csc.fi/english/pages/elmer) which provides the full machinery for the complex finite element procedure and is fully parallel (mesh partitioning with OpenMPI communication). Elmer is mainly written in Fortran 90 and targets essentially traditional processors as the code base was not initially written to run on modern coprocessors (yet adding support for the recently introduced x86 based coprocessors is possible). Furthermore, a truly modular and object-oriented implementation is required for quick adaptation to fast evolving capabilities in hardware (Fortran 2003 provides an object-oriented programming model while not being clean and requiring a tricky refactoring of Elmer code). In this work, the object-oriented, coprocessor-accelerated finite element code Sainou is introduced. Sainou is an Elmer fork which is reimplemented in Objective C and used for experimenting with ice sheet models running on coprocessors, essentially GPU devices. GPUs are highly parallel processors that provide opportunities for fine-grained parallelization of the full Stokes problem using the standard OpenCL language (http://www.khronos.org/opencl/) to access the device. Sainou is built upon a collection of Objective C base classes that service a modular kernel (itself a base class) which provides the core methods to solve the finite element problem. An early implementation of Sainou will be presented with emphasis on the object architecture and the strategies of parallelizations. The computation of a simple heat conduction problem is used to test the implementation which also provides experimental support for running the global matrix assembly on GPU.

Resonance assignment of the NMR spectra of disordered proteins using a multi-objective non-dominated sorting genetic algorithm.

PubMed

Yang, Yu; Fritzsching, Keith J; Hong, Mei

2013-11-01

A multi-objective genetic algorithm is introduced to predict the assignment of protein solid-state NMR (SSNMR) spectra with partial resonance overlap and missing peaks due to broad linewidths, molecular motion, and low sensitivity. This non-dominated sorting genetic algorithm II (NSGA-II) aims to identify all possible assignments that are consistent with the spectra and to compare the relative merit of these assignments. Our approach is modeled after the recently introduced Monte-Carlo simulated-annealing (MC/SA) protocol, with the key difference that NSGA-II simultaneously optimizes multiple assignment objectives instead of searching for possible assignments based on a single composite score. The multiple objectives include maximizing the number of consistently assigned peaks between multiple spectra ("good connections"), maximizing the number of used peaks, minimizing the number of inconsistently assigned peaks between spectra ("bad connections"), and minimizing the number of assigned peaks that have no matching peaks in the other spectra ("edges"). Using six SSNMR protein chemical shift datasets with varying levels of imperfection that was introduced by peak deletion, random chemical shift changes, and manual peak picking of spectra with moderately broad linewidths, we show that the NSGA-II algorithm produces a large number of valid and good assignments rapidly. For high-quality chemical shift peak lists, NSGA-II and MC/SA perform similarly well. However, when the peak lists contain many missing peaks that are uncorrelated between different spectra and have chemical shift deviations between spectra, the modified NSGA-II produces a larger number of valid solutions than MC/SA, and is more effective at distinguishing good from mediocre assignments by avoiding the hazard of suboptimal weighting factors for the various objectives. These two advantages, namely diversity and better evaluation, lead to a higher probability of predicting the correct assignment for a larger number of residues. On the other hand, when there are multiple equally good assignments that are significantly different from each other, the modified NSGA-II is less efficient than MC/SA in finding all the solutions. This problem is solved by a combined NSGA-II/MC algorithm, which appears to have the advantages of both NSGA-II and MC/SA. This combination algorithm is robust for the three most difficult chemical shift datasets examined here and is expected to give the highest-quality de novo assignment of challenging protein NMR spectra.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meddens, Marjolein B. M.; Liu, Sheng; Finnegan, Patrick S.

Here, we have developed a method for performing light-sheet microscopy with a single high numerical aperture lens by integrating reflective side walls into a microfluidic chip. These 45° side walls generate light-sheet illumination by reflecting a vertical light-sheet into the focal plane of the objective. Light-sheet illumination of cells loaded in the channels increases image quality in diffraction limited imaging via reduction of out-of-focus background light. Single molecule super-resolution is also improved by the decreased background resulting in better localization precision and decreased photo-bleaching, leading to more accepted localizations overall and higher quality images. Moreover, 2D and 3D single moleculemore » super-resolution data can be acquired faster by taking advantage of the increased illumination intensities as compared to wide field, in the focused light-sheet.« less

Chemical vapor deposition growth

NASA Technical Reports Server (NTRS)

Ruth, R. P.; Manasevit, H. M.; Kenty, J. L.; Moudy, L. A.; Simpson, W. I.; Yang, J. J.

1976-01-01

The chemical vapor deposition (CVD) method for the growth of Si sheet on inexpensive substrate materials is investigated. The objective is to develop CVD techniques for producing large areas of Si sheet on inexpensive substrate materials, with sheet properties suitable for fabricating solar cells meeting the technical goals of the Low Cost Silicon Solar Array Project. Specific areas covered include: (1) modification and test of existing CVD reactor system; (2) identification and/or development of suitable inexpensive substrate materials; (3) experimental investigation of CVD process parameters using various candidate substrate materials; (4) preparation of Si sheet samples for various special studies, including solar cell fabrication; (5) evaluation of the properties of the Si sheet material produced by the CVD process; and (6) fabrication and evaluation of experimental solar cell structures, using standard and near-standard processing techniques.

An efficient randomized algorithm for contact-based NMR backbone resonance assignment.

PubMed

Kamisetty, Hetunandan; Bailey-Kellogg, Chris; Pandurangan, Gopal

2006-01-15

Backbone resonance assignment is a critical bottleneck in studies of protein structure, dynamics and interactions by nuclear magnetic resonance (NMR) spectroscopy. A minimalist approach to assignment, which we call 'contact-based', seeks to dramatically reduce experimental time and expense by replacing the standard suite of through-bond experiments with the through-space (nuclear Overhauser enhancement spectroscopy, NOESY) experiment. In the contact-based approach, spectral data are represented in a graph with vertices for putative residues (of unknown relation to the primary sequence) and edges for hypothesized NOESY interactions, such that observed spectral peaks could be explained if the residues were 'close enough'. Due to experimental ambiguity, several incorrect edges can be hypothesized for each spectral peak. An assignment is derived by identifying consistent patterns of edges (e.g. for alpha-helices and beta-sheets) within a graph and by mapping the vertices to the primary sequence. The key algorithmic challenge is to be able to uncover these patterns even when they are obscured by significant noise. This paper develops, analyzes and applies a novel algorithm for the identification of polytopes representing consistent patterns of edges in a corrupted NOESY graph. Our randomized algorithm aggregates simplices into polytopes and fixes inconsistencies with simple local modifications, called rotations, that maintain most of the structure already uncovered. In characterizing the effects of experimental noise, we employ an NMR-specific random graph model in proving that our algorithm gives optimal performance in expected polynomial time, even when the input graph is significantly corrupted. We confirm this analysis in simulation studies with graphs corrupted by up to 500% noise. Finally, we demonstrate the practical application of the algorithm on several experimental beta-sheet datasets. Our approach is able to eliminate a large majority of noise edges and to uncover large consistent sets of interactions. Our algorithm has been implemented in the platform-independent Python code. The software can be freely obtained for academic use by request from the authors.

NMR analysis of cross strand aromatic interactions in an 8 residue hairpin and a 14 residue three stranded β-sheet peptide.

PubMed

Sonti, Rajesh; Rai, Rajkishor; Ragothama, Srinivasarao; Balaram, Padmanabhan

2012-12-13

Cross strand aromatic interactions between a facing pair of phenylalanine residues in antiparallel β-sheet structures have been probed using two structurally defined model peptides. The octapeptide Boc-LFV(D)P(L)PLFV-OMe (peptide 1) favors the β-hairpin conformation nucleated by the type II' β-turn formed by the (D)Pro-(L)Pro segment, placing Phe2 and Phe7 side chains in proximity. Two centrally positioned (D)Pro-(L)Pro segments facilitate the three stranded β-sheet formation in the 14 residue peptide Boc-LFV(D)P(L)PLFVA(D)P(L)PLFV-OMe (peptide 2) in which the Phe2/Phe7 orientations are similar to that in the octapeptide. The anticipated folded conformations of peptides 1 and 2 are established by the delineation of intramolecularly hydrogen bonded NH groups and by the observation of specific cross strand NOEs. The observation of ring current shifted aromatic protons is a diagnostic of close approach of the Phe2 and Phe7 side chains. Specific assignment of aromatic proton resonances using HSQC and HSQC-TOCSY methods allow an analysis of interproton NOEs between the spatially proximate aromatic rings. This approach facilitates specific assignments in systems containing multiple aromatic rings in spectra at natural abundance. Evidence is presented for a dynamic process which invokes a correlated conformational change about the C(α)-C(β)(χ(1)) bond for the pair of interacting Phe residues. NMR results suggest that aromatic ring orientations observed in crystals are maintained in solution. Anomalous temperature dependence of ring current induced proton chemical shifts suggests that solvophobic effects may facilitate aromatic ring clustering in apolar solvents.

Enhanced osseointegration of titanium implants in a rat model of osteoporosis using multilayer bone mesenchymal stem cell sheets

PubMed Central

Duan, Yan; Ma, Wei; Li, Dehua; Wang, Tongfei; Liu, Baolin

2017-01-01

The present study aimed to investigate whether bone marrow-derived mesenchymal stem cell (BMSC) sheets combined with titanium implants enhanced implant osseointegration in an ovariectomized (OVX) rat model of osteoporosis. Sprague-Dawley rats were randomly assigned into a test group and control group. Allogenic BMSCs were collected from the rats, cultured and stored via cryopreservation. At 6 months post-ovariectomy, establishment of the OVX model was confirmed by micro-computed tomography (CT) measurements. BMSC sheets were subsequently layered and wrapped over titanium implants for implantation. Unmodified implants served as the control. At 8 weeks post-implantation, samples were observed by micro-CT reconstruction and histomorphometric evaluation. Micro-CT reconstruction identified a marked improvement in the surrounding bone volume following treatment, with data analyses indicating a significant increase in bone volume in the BMSC-implant group compared with the control implant group (P<0.05). In addition, histological staining identified new bone formation and an increased rate of bone-implant contact surrounding the BMSC-implant constructs. These results indicate that the use of BMSC sheets as a novel tissue engineering approach improves the osseointegration of titanium implants in an osteoporosis model. This method may expand the operative indications in patients with osteoporosis and improve the success rate of clinical dental implant treatments. PMID:29250137

The cosmic web and the orientation of angular momenta

NASA Astrophysics Data System (ADS)

Libeskind, Noam I.; Hoffman, Yehuda; Knebe, Alexander; Steinmetz, Matthias; Gottlöber, Stefan; Metuki, Ofer; Yepes, Gustavo

2012-03-01

We use a 64 h-1 Mpc dark-matter-only cosmological simulation to examine the large-scale orientation of haloes and substructures with respect to the cosmic web. A web classification scheme based on the velocity shear tensor is used to assign to each halo in the simulation a web type: knot, filament, sheet or void. Using ˜106 haloes that span ˜3 orders of magnitude in mass, the orientation of the halo's spin and the orbital angular momentum of subhaloes with respect to the eigenvectors of the shear tensor is examined. We find that the orbital angular momentum of subhaloes tends to align with the intermediate eigenvector of the velocity shear tensor for all haloes in knots, filaments and sheets. This result indicates that the kinematics of substructures located deep within the virialized regions of a halo is determined by its infall which in turn is determined by the large-scale velocity shear, a surprising result given the virialized nature of haloes. The non-random nature of subhalo accretion is thus imprinted on the angular momentum measured at z= 0. We also find that the haloes' spin axis is aligned with the third eigenvector of the velocity shear tensor in filaments and sheets: the halo spin axis points along filaments and lies in the plane of cosmic sheets.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fogh, R.H.; Mabbutt, B.C.; Kem, W.R.

Sequence-specific assignments are reported for the 500-MHz H nuclear magnetic resonance (NMR) spectrum of the 48-residue polypeptide neurotoxin I from the sea anemone Stichodactyla helianthus (Sh I). Spin systems were first identified by using two-dimensional relayed or multiple quantum filtered correlation spectroscopy, double quantum spectroscopy, and spin lock experiments. Specific resonance assignments were then obtained from nuclear Overhauser enhancement (NOE) connectivities between protons from residues adjacent in the amino acid sequence. Of a total of 265 potentially observable resonances, 248 (i.e., 94%) were assigned, arising from 39 completely and 9 partially assigned amino acid spin systems. The secondary structure ofmore » Sh I was defined on the basis of the pattern of sequential NOE connectivities. NOEs between protons on separate strands of the polypeptide backbone, and backbone amide exchange rates. Sh I contains a four-stranded antiparallel {beta}-sheet encompassing residues 1-5, 16-24, 30-33, and 40-46, with a {beta}-bulge at residues 17 and 18 and a reverse turn, probably a type II {beta}-turn, involving residues 27-30. No evidence of {alpha}-helical structure was found.« less

Improving the knowledge of labour and delivery nurses in India: a randomized controlled trial of mentoring and case sheets in primary care centres.

PubMed

Bradley, Janet; Jayanna, Krishnamurthy; Shaw, Souradet; Cunningham, Troy; Fischer, Elizabeth; Mony, Prem; Ramesh, B M; Moses, Stephen; Avery, Lisa; Crockett, Maryanne; Blanchard, James F

2017-01-07

Birthing in health facilities in India has increased over the last few years, yet maternal and neonatal mortality rates remain high. Clinical mentoring with case sheets or checklists for nurses is viewed as essential for on-going knowledge transfer, particularly where basic training is inadequate. This paper summarizes a study of the effect of such a programme on staff knowledge and skills in a randomized trial of 295 nurses working in 108 Primary Health Centres (PHCs) in Karnataka, India. Stratifying by district, half of the PHCs were randomly assigned to be intervention sites and provided with regular mentoring visits where case sheet/checklists were a central job and teaching aid, and half to be control sites, where no support was provided except provision of case sheets. Nurses' knowledge and skills around normal labour, labour complications and neonate issues were tested before the intervention began and again one year later. Univariate and multivariate analyses were conducted to examine the effect of mentoring and case sheets. Overall, on none of the 3 measures, did case sheet use without mentoring add anything to the basic nursing training when controlling for other factors. Only individuals who used both case-sheets and received mentoring scored significantly higher on the normal labour and neonate indices, scoring almost twice as high as those who only used case-sheets. This group was also associated with significantly higher scores on the complications of labour index, with their scores 2.3 times higher on average than the case sheet only control group. Individuals from facilities with 21 or more deliveries in a month tended to fare worse on all 3 indices. There were no differences in outcomes according to district or years of experience. This study demonstrates that provision of case sheets or checklists alone is insufficient to improve knowledge and practices. However, on-site mentoring in combination with case sheets can have a demonstrable effect on improving nurse knowledge and skills around essential obstetric and neonatal care in remote rural areas of India. We recommend scaling up of this mentoring model in order to improve staff knowledge and skills and reduce maternal and neonatal mortality in India. This study is registered at clinicaltrials.gov, Identifier No. NCT02004912 , November 27, 2013.

Magneto-hydrodynamics of coupled fluid-sheet interface with mass suction and blowing

NASA Astrophysics Data System (ADS)

Ahmad, R.

2016-01-01

There are large number of studies which prescribe the kinematics of the sheet and ignore the sheet's mechanics. However, the current boundary layer analysis investigates the mechanics of both the electrically conducting fluid and a permeable sheet, which makes it distinct from the other studies in the literature. One of the objectives of the current study is to (i) examine the behaviour of magnetic field effect for both the surface and the electrically conducting fluid (ii) investigate the heat and mass transfer between a permeable sheet and the surrounding electrically conducting fluid across the hydro, thermal and mass boundary layers. Self-similar solutions are obtained by considering the RK45 technique. Analytical solution is also found for the stretching sheet case. The skin friction dual solutions are presented for various types of sheet. The influence of pertinent parameters on the dimensionless velocity, shear stress, temperature, mass concentration, heat and mass transfer rates on the fluid-sheet interface is presented graphically as well as numerically. The obtained results are of potential benefit for studying the electrically conducting flow over various soft surfaces such as synthetic plastics, soft silicone sheet and soft synthetic rubber sheet. These surfaces are easily deformed by thermal fluctuations or thermal stresses.

Detailed test objectives for the extended long tank delta launch vehicle, spacecraft: AE-C

NASA Technical Reports Server (NTRS)

1973-01-01

The test objectives for the extended long tank Delta Launch Vehicle are presented. The subjects discussed are: (1) mission and vehicle objectives, (2) nominal flight plan, (3) trajectory analysis, (4) weight summary and inflight mass properties, and (5) instrumentation channel assignments and ground monitoring assignments.

Energy. Overview: ERIC Fact Sheet No. 6.

ERIC Educational Resources Information Center

Arrington, Larry

This fact sheet provides a basic overview of energy problems and programs in the United States and discusses the role that vocational education can play in solving those problems. The National Energy Plan is described including its objectives, strategies, and seven legislative acts: (1) The National Energy Conservation Act; (2) The Power Plant and…

Electrical Experiments. VT-214-12-5. Part V. Transformers.

ERIC Educational Resources Information Center

Connecticut State Dept. of Education, Hartford. Div. of Vocational Education.

Designed for high school electronics students, this fifth document in a series of six electrical learning activity packages focuses on transformers. An introductory section gives the objective for the activities, an introduction, and an outline of the content. The remainder of the activity book is comprised of information sheets and job sheets on…

Multi-Objective Parallel Test-Sheet Composition Using Enhanced Particle Swarm Optimization

ERIC Educational Resources Information Center

Ho, Tsu-Feng; Yin, Peng-Yeng; Hwang, Gwo-Jen; Shyu, Shyong Jian; Yean, Ya-Nan

2009-01-01

For large-scale tests, such as certification tests or entrance examinations, the composed test sheets must meet multiple assessment criteria. Furthermore, to fairly compare the knowledge levels of the persons who receive tests at different times owing to the insufficiency of available examination halls or the occurrence of certain unexpected…

Programmable matter by folding

PubMed Central

Hawkes, E.; An, B.; Benbernou, N. M.; Tanaka, H.; Kim, S.; Demaine, E. D.; Rus, D.; Wood, R. J.

2010-01-01

Programmable matter is a material whose properties can be programmed to achieve specific shapes or stiffnesses upon command. This concept requires constituent elements to interact and rearrange intelligently in order to meet the goal. This paper considers achieving programmable sheets that can form themselves in different shapes autonomously by folding. Past approaches to creating transforming machines have been limited by the small feature sizes, the large number of components, and the associated complexity of communication among the units. We seek to mitigate these difficulties through the unique concept of self-folding origami with universal crease patterns. This approach exploits a single sheet composed of interconnected triangular sections. The sheet is able to fold into a set of predetermined shapes using embedded actuation. To implement this self-folding origami concept, we have developed a scalable end-to-end planning and fabrication process. Given a set of desired objects, the system computes an optimized design for a single sheet and multiple controllers to achieve each of the desired objects. The material, called programmable matter by folding, is an example of a system capable of achieving multiple shapes for multiple functions. PMID:20616049

Programmable matter by folding.

PubMed

Hawkes, E; An, B; Benbernou, N M; Tanaka, H; Kim, S; Demaine, E D; Rus, D; Wood, R J

2010-07-13

Programmable matter is a material whose properties can be programmed to achieve specific shapes or stiffnesses upon command. This concept requires constituent elements to interact and rearrange intelligently in order to meet the goal. This paper considers achieving programmable sheets that can form themselves in different shapes autonomously by folding. Past approaches to creating transforming machines have been limited by the small feature sizes, the large number of components, and the associated complexity of communication among the units. We seek to mitigate these difficulties through the unique concept of self-folding origami with universal crease patterns. This approach exploits a single sheet composed of interconnected triangular sections. The sheet is able to fold into a set of predetermined shapes using embedded actuation. To implement this self-folding origami concept, we have developed a scalable end-to-end planning and fabrication process. Given a set of desired objects, the system computes an optimized design for a single sheet and multiple controllers to achieve each of the desired objects. The material, called programmable matter by folding, is an example of a system capable of achieving multiple shapes for multiple functions.

40 CFR 305.4 - Powers and duties of the Review Officer and the Presiding Officer; disqualification.

Code of Federal Regulations, 2010 CFR

2010-07-01

... notify the parties of his assignment pursuant to § 305.4(c). The Presiding Officer shall conduct a fair... findings of fact, conclusions of law, and a final order; (11) Assess costs of the proceeding pursuant to... assignment of the Presiding Officer, make any objection to his assignment. Otherwise, any objections to the...

Geometry of thin liquid sheet flows

NASA Technical Reports Server (NTRS)

Chubb, Donald L.; Calfo, Frederick D.; Mcconley, Marc W.; Mcmaster, Matthew S.; Afjeh, Abdollah A.

1994-01-01

Incompresible, thin sheet flows have been of research interest for many years. Those studies were mainly concerned with the stability of the flow in a surrounding gas. Squire was the first to carry out a linear, invicid stability analysis of sheet flow in air and compare the results with experiment. Dombrowski and Fraser did an experimental study of the disintegration of sheet flows using several viscous liquids. They also detected the formulation of holes in their sheet flows. Hagerty and Shea carried out an inviscid stability analysis and calculated growth rates with experimental values. They compared their calculated growth rates with experimental values. Taylor studied extensively the stability of thin liquid sheets both theoretically and experimentally. He showed that thin sheets in a vacuum are stable. Brown experimentally investigated thin liquid sheet flows as a method of application of thin films. Clark and Dumbrowski carried out second-order stability analysis for invicid sheet flows. Lin introduced viscosity into the linear stability analysis of thin sheet flows in a vacuum. Mansour and Chigier conducted an experimental study of the breakup of a sheet flow surrounded by high-speed air. Lin et al. did a linear stability analysis that included viscosity and a surrounding gas. Rangel and Sirignano carried out both a linear and nonlinear invisid stability analysis that applies for any density ratio between the sheet liquid and the surrounding gas. Now there is renewed interest in sheet flows because of their possible application as low mass radiating surfaces. The objective of this study is to investigate the fluid dynamics of sheet flows that are of interest for a space radiator system. Analytical expressions that govern the sheet geometry are compared with experimental results. Since a space radiator will operate in a vacuum, the analysis does not include any drag force on the sheet flow.

Case in Point: Stronach v. Virginia State U. (2008): Does Academic Freedom Give a Professor the Final Say on Grades?

ERIC Educational Resources Information Center

White, Lawrence

2008-01-01

Virginia State University Carey E. Stronach assigned an undergraduate a final grade of D after the student had failed three classroom quizzes. The student, who claimed to have received A's on two of the quizzes, submitted fax copies of his score sheets to Stronach, who concluded that the student had doctored his scores. The student appealed to the…

¹⁵N, ¹³C and ¹H resonance assignments and secondary structure determination of a variable heavy domain of a heavy chain antibody.

PubMed

Prosser, Christine E; Waters, Lorna C; Muskett, Frederick W; Veverka, Vaclav; Addis, Philip W; Griffin, Laura M; Baker, Terry S; Lawson, Alastair D G; Wernery, Ulrich; Kinne, Jorg; Henry, Alistair J; Taylor, Richard J; Carr, Mark D

2014-04-01

Heavy chain antibodies differ in structure to conventional antibodies lacking both the light chain and the first heavy chain constant domain (CH1). Characteristics of the antigen-binding variable heavy domain of the heavy chain antibody (VHH) including the smaller size, high solubility and stability make them an attractive alternative to more traditional antibody fragments for detailed NMR-based structural analysis. Here we report essentially complete backbone and side chain (15)N, (13)C and (1)H assignments for a free VHH. Analysis of the backbone chemical shift data obtained indicates that the VHH is comprised predominantly of β-sheets corresponding to nearly 60% of the protein backbone.

Deformation Analysis of RC Ties Externally Strengthened with FRP Sheets

NASA Astrophysics Data System (ADS)

Gribniak, V.; Arnautov, A. K.; Kaklauskas, G.; Jakstaite, R.; Tamulenas, V.; Gudonis, E.

2014-11-01

The current study has two objectives: to validate the ability of the Atena finite-element software to estimate the deformations of reinforced concrete (RC) elements strengthened with fiber-reinforced polymer (FRP) sheets and to assess the effect of FRP-to-concrete bond strength on the results of numerical simulation. It is shown that the bond strength has to be selected according to the overall stiffness of the composite element. The numerical results found are corroborated experimentally by tensile tests of RC elements strengthened with basalt FRP sheets.

3D surface parameterization using manifold learning for medial shape representation

NASA Astrophysics Data System (ADS)

Ward, Aaron D.; Hamarneh, Ghassan

2007-03-01

The choice of 3D shape representation for anatomical structures determines the effectiveness with which segmentation, visualization, deformation, and shape statistics are performed. Medial axis-based shape representations have attracted considerable attention due to their inherent ability to encode information about the natural geometry of parts of the anatomy. In this paper, we propose a novel approach, based on nonlinear manifold learning, to the parameterization of medial sheets and object surfaces based on the results of skeletonization. For each single-sheet figure in an anatomical structure, we skeletonize the figure, and classify its surface points according to whether they lie on the upper or lower surface, based on their relationship to the skeleton points. We then perform nonlinear dimensionality reduction on the skeleton, upper, and lower surface points, to find the intrinsic 2D coordinate system of each. We then center a planar mesh over each of the low-dimensional representations of the points, and map the meshes back to 3D using the mappings obtained by manifold learning. Correspondence between mesh vertices, established in their intrinsic 2D coordinate spaces, is used in order to compute the thickness vectors emanating from the medial sheet. We show results of our algorithm on real brain and musculoskeletal structures extracted from MRI, as well as an artificial multi-sheet example. The main advantages to this method are its relative simplicity and noniterative nature, and its ability to correctly compute nonintersecting thickness vectors for a medial sheet regardless of both the amount of coincident bending and thickness in the object, and of the incidence of local concavities and convexities in the object's surface.

Directory of research projects: Planetary geology and geophysics program

NASA Technical Reports Server (NTRS)

Holt, Henry (Editor)

1992-01-01

Information about currently funded scientific research within the Planetary Geology and Geophysics Program is provided. The directory consists of the proposal summary sheet from each proposal funded under the program during Fiscal Year 1992. The sheets provide information about the research project, including title, principal investigator, institution, summary of research objectives, past accomplishments, and proposed new investigations.

Fuels planning: science synthesis and integration; social issues fact sheet 18: Issues affecting social acceptability of fuels treatments

Treesearch

Christine Esposito

2006-01-01

Researchers have tried to understand how information about forest management can influence a person's landscape preferences and aesthetic appreciation. These findings are relevant for fuels management projects, since these projects are often characterized by conflicts between aesthetic and ecological objectives. This fact sheet discusses different aspects and ways...

Moral Dilemmas/Value Sheets: Writing for Content-Centered Social Studies Classrooms.

ERIC Educational Resources Information Center

Stahl, Robert J.; And Others

The purpose of the paper is to stress the development of content-centered classroom activities useful for attaining values clarification and/or moral development goals. The objective is to help teachers understand the formulation of content-centered learning activities so that they will be able to plan and produce their own value sheets or moral…

High-speed volume measurement system and method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lane, Michael H.; Doyle, Jr., James L.; Brinkman, Michael J.

2017-12-12

Disclosed is a volume sensor having first, second, and third laser sources emitting first, second, and third laser beams; first, second, and third beam splitters splitting the first, second, and third laser beams into first, second, and third beam pairs; first, second, and third optical assemblies expanding the first, second, and third beam pairs into first, second, and third pairs of parallel beam sheets; fourth, fifth, and sixth optical assemblies focusing the first, second, and third beam sheet pairs into fourth, fifth, and sixth beam pairs; and first, second, and third detector pairs receiving the fourth, fifth, and sixth beammore » pairs and converting a change in intensity of at least one of the beam pairs resulting from an object passing through at least one of the first, second, and third parallel beam sheets into at least one electrical signal proportional to a three-dimensional representation of the object.« less

Hazard banding in compliance with the new Globally Harmonised System (GHS) for use in control banding tools.

PubMed

Arnone, Mario; Koppisch, Dorothea; Smola, Thomas; Gabriel, Stefan; Verbist, Koen; Visser, Remco

2015-10-01

Many control banding tools use hazard banding in risk assessments for the occupational handling of hazardous substances. The outcome of these assessments can be combined with advice for the required risk management measures (RMMs). The Globally Harmonised System of Classification and Labelling of Chemicals (GHS) has resulted in a change in the hazard communication elements, i.e. Hazard (H) statements instead of Risk-phrases. Hazard banding schemes that depend on the old form of safety information have to be adapted to the new rules. The purpose of this publication is to outline the rationales for the assignment of hazard bands to H statements under the GHS. Based on this, this publication proposes a hazard banding scheme that uses the information from the safety data sheets as the basis for assignment. The assignment of hazard bands tiered according to the severity of the underlying hazards supports the important principle of substitution. Additionally, the set of assignment rules permits an exposure-route-specific assignment of hazard bands, which is necessary for the proposed route-specific RMMs. Ideally, all control banding tools should apply the same assignment rules. This GHS-compliant hazard banding scheme can hopefully help to establish a unified hazard banding strategy in the various control banding tools. Copyright © 2015 Elsevier Inc. All rights reserved.

Program for Arctic Regional Climate Assessment (PARCA)

NASA Technical Reports Server (NTRS)

Gogineni, Sivaprasad; Thomas, Robert H.; Abdalati, Waleed (Editor)

1999-01-01

The Program for Arctic Regional Climate Assessment (PARCA) is a NASA-sponsored initiative with the prime objective of understanding the mass balance of the Greenland ice sheet. In October 1998, PARCA investigators met to review activities of the previous year, assess the program's progress, and plan future investigations directed at accomplishing that objective. Some exciting results were presented and discussed, including evidence of dramatic thinning of the ice sheet near the southeastern coast. Details of the investigations and many of the accomplishments are given in this report, but major highlights are given in the Executive Summary of the report.

Skiving stacked sheets of paper into test paper for rapid and multiplexed assay

PubMed Central

Yang, Mingzhu; Zhang, Wei; Yang, Junchuan; Hu, Binfeng; Cao, Fengjing; Zheng, Wenshu; Chen, Yiping; Jiang, Xingyu

2017-01-01

This paper shows that stacked sheets of paper preincubated with different biological reagents and skiving them into uniform test paper sheets allow mass manufacturing of multiplexed immunoassay devices and simultaneous detection of multiplex targets that can be read out by a barcode scanner. The thickness of one sheet of paper can form the width of a module for the barcode; when stacked, these sheets of paper can form a series of barcodes representing the targets, depending on the color contrast provided by a colored precipitate of an immunoassay. The uniform thickness of sheets of paper allows high-quality signal readout. The manufacturing method allows highly efficient fabrication of the materials and substrates for a straightforward assay of targets that range from drugs of abuse to biomarkers of blood-transmitted infections. In addition, as a novel alternative to the conventional point-of-care testing method, the paper-based barcode assay system can provide highly efficient, accurate, and objective diagnoses. PMID:29214218

Position And Force Control For Multiple-Arm Robots

NASA Technical Reports Server (NTRS)

Hayati, Samad A.

1988-01-01

Number of arms increased without introducing undue complexity. Strategy and computer architecture developed for simultaneous control of positions of number of robot arms manipulating same object and of forces and torques that arms exert on object. Scheme enables coordinated manipulation of object, causing it to move along assigned trajectory and be subjected to assigned internal forces and torques.

Chemical vapor deposition growth

NASA Technical Reports Server (NTRS)

Ruth, R. P.; Manasevit, H. M.; Campbell, A. G.; Johnson, R. E.; Kenty, J. L.; Moudy, L. A.; Shaw, G. L.; Simpson, W. I.; Yang, J. J.

1978-01-01

The objective was to investigate and develop chemical vapor deposition (CVD) techniques for the growth of large areas of Si sheet on inexpensive substrate materials, with resulting sheet properties suitable for fabricating solar cells that would meet the technical goals of the Low Cost Silicon Solar Array Project. The program involved six main technical tasks: (1) modification and test of an existing vertical-chamber CVD reactor system; (2) identification and/or development of suitable inexpensive substrate materials; (3) experimental investigation of CVD process parameters using various candidate substrate materials; (4) preparation of Si sheet samples for various special studies, including solar cell fabrication; (5) evaluation of the properties of the Si sheet material produced by the CVD process; and (6) fabrication and evaluation of experimental solar cell structures, using impurity diffusion and other standard and near-standard processing techniques supplemented late in the program by the in situ CVD growth of n(+)/p/p(+) sheet structures subsequently processed into experimental cells.

Asian Americans: A Status Report. Fact Sheet for the Chairman, Select Committee on Hunger, House of Representatives.

ERIC Educational Resources Information Center

General Accounting Office, Washington, DC. Div. of Human Resources.

This fact sheet presents information on the status of Asians in the United States. The following sections are included: (1) "Introduction," which includes Asian American population statistics, and the objectives, scope, and methodology of the study; (2) "Overall Income and Employment Status Comparable With U.S. Population, But Varies Widely Among…

Facts on Grants, 1982. A Report on Grant-Making.

ERIC Educational Resources Information Center

Mott (C.S.) Foundation, Flint, MI.

Summaries of 361 grants made in 1982 by the Charles Stewart Mott Foundation are presented. The guide contains fact sheets on grants for $15,000 or more; all grants for amounts under $15,000 are listed with brief descriptions. Most of the fact sheets provide information on how the grants meet the objectives of the Foundation, what they might…

Land, Ocean and Ice sheet surface elevation retrieval from CALIPSO lidar measurements

NASA Astrophysics Data System (ADS)

Lu, X.; Hu, Y.

2013-12-01

Since launching in April 2006 the main objective of the Cloud-Aerosol Lidar and Infrared Pathfinder Satellite Observations (CALIPSO) mission has been studying the climate impact of clouds and aerosols in the atmosphere. However, CALIPSO also collects information about other components of the Earth's ecosystem, such as lands, oceans and polar ice sheets. The objective of this study is to propose a Super-Resolution Altimetry (SRA) technique to provide high resolution of land, ocean and polar ice sheet surface elevation from CALIPSO single shot lidar measurements (70 m spot size). The land surface results by the new technique agree with the United States Geological Survey (USGS) National Elevation Database (NED) high-resolution elevation maps, and the ice sheet surface results in the region of Greenland and Antarctic compare very well with the Ice, Cloud and land Elevation Satellite (ICESat) laser altimetry measurements. The comparisons suggest that the obtained CALIPSO surface elevation information by the new technique is accurate to within 1 m. The effects of error sources on the retrieved surface elevation are discussed. Based on the new technique, the preliminary data products of along-track topography retrieved from the CALIPSO lidar measurements is available to the altimetry community for evaluation.

Metals. Industrial Arts. Performance Objectives, Junior High School.

ERIC Educational Resources Information Center

Bunch, Edwood; And Others

Several intermediate performance objectives and corresponding criterion measures are listed for a metals course for seventh, eighth, and ninth grade students. The seventh grade section includes 13 terminal objectives for a 9-week course and provides exploratory units in bench metals and sheet metals. Industrial materials and processes receive…

Three-dimensional structure of the human immunodeficiency virus type 1 matrix protein.

PubMed

Massiah, M A; Starich, M R; Paschall, C; Summers, M F; Christensen, A M; Sundquist, W I

1994-11-25

The HIV-1 matrix protein forms an icosahedral shell associated with the inner membrane of the mature virus. Genetic analyses have indicated that the protein performs important functions throughout the viral life-cycle, including anchoring the transmembrane envelope protein on the surface of the virus, assisting in viral penetration, transporting the proviral integration complex across the nuclear envelope, and localizing the assembling virion to the cell membrane. We now report the three-dimensional structure of recombinant HIV-1 matrix protein, determined at high resolution by nuclear magnetic resonance (NMR) methods. The HIV-1 matrix protein is the first retroviral matrix protein to be characterized structurally and only the fourth HIV-1 protein of known structure. NMR signal assignments required recently developed triple-resonance (1H, 13C, 15N) NMR methodologies because signals for 91% of 132 assigned H alpha protons and 74% of the 129 assignable backbone amide protons resonate within chemical shift ranges of 0.8 p.p.m. and 1 p.p.m., respectively. A total of 636 nuclear Overhauser effect-derived distance restraints were employed for distance geometry-based structure calculations, affording an average of 13.0 NMR-derived distance restraints per residue for the experimentally constrained amino acids. An ensemble of 25 refined distance geometry structures with penalties (sum of the squares of the distance violations) of 0.32 A2 or less and individual distance violations under 0.06 A was generated; best-fit superposition of ordered backbone heavy atoms relative to mean atom positions afforded root-mean-square deviations of 0.50 (+/- 0.08) A. The folded HIV-1 matrix protein structure is composed of five alpha-helices, a short 3(10) helical stretch, and a three-strand mixed beta-sheet. Helices I to III and the 3(10) helix pack about a central helix (IV) to form a compact globular domain that is capped by the beta-sheet. The C-terminal helix (helix V) projects away from the beta-sheet to expose carboxyl-terminal residues essential for early steps in the HIV-1 infectious cycle. Basic residues implicated in membrane binding and nuclear localization functions cluster about an extruded cationic loop that connects beta-strands 1 and 2. The structure suggests that both membrane binding and nuclear localization may be mediated by complex tertiary structures rather than simple linear determinants.

Effect of Temperature and Sheet Temper on Isothermal Solidification Kinetics in Clad Aluminum Brazing Sheet

NASA Astrophysics Data System (ADS)

Benoit, Michael J.; Whitney, Mark A.; Wells, Mary A.; Winkler, Sooky

2016-09-01

Isothermal solidification (IS) is a phenomenon observed in clad aluminum brazing sheets, wherein the amount of liquid clad metal is reduced by penetration of the liquid clad into the core. The objective of the current investigation is to quantify the rate of IS through the use of a previously derived parameter, the Interface Rate Constant (IRC). The effect of peak temperature and initial sheet temper on IS kinetics were investigated. The results demonstrated that IS is due to the diffusion of silicon (Si) from the liquid clad layer into the solid core. Reduced amounts of liquid clad at long liquid duration times, a roughened sheet surface, and differences in resolidified clad layer morphology between sheet tempers were observed. Increased IS kinetics were predicted at higher temperatures by an IRC model as well as by experimentally determined IRC values; however, the magnitudes of these values are not in good agreement due to deficiencies in the model when applied to alloys. IS kinetics were found to be higher for sheets in the fully annealed condition when compared with work-hardened sheets, due to the influence of core grain boundaries providing high diffusivity pathways for Si diffusion, resulting in more rapid liquid clad penetration.

Monitoring Sand Sheets and Dunes

NASA Image and Video Library

2017-06-12

NASA's Mars Reconnaissance Orbiter (MRO) captured this crater featuring sand dunes and sand sheets on its floor. What are sand sheets? Snow fall on Earth is a good example of sand sheets: when it snows, the ground gets blanketed with up to a few meters of snow. The snow mantles the ground and "mimics" the underlying topography. Sand sheets likewise mantle the ground as a relatively thin deposit. This kind of environment has been monitored by HiRISE since 2007 to look for movement in the ripples covering the dunes and sheets. This is how scientists who study wind-blown sand can track the amount of sand moving through the area and possibly where the sand came from. Using the present environment is crucial to understanding the past: sand dunes, sheets, and ripples sometimes become preserved as sandstone and contain clues as to how they were deposited The map is projected here at a scale of 25 centimeters (9.8 inches) per pixel. [The original image scale is 25 centimeters (9.8 inches) per pixel (with 1 x 1 binning); objects on the order of 75 centimeters (29.5 inches) across are resolved.] North is up. https://photojournal.jpl.nasa.gov/catalog/PIA21757

A Dyadic Interactive Approach to the Study of Leader Behavior

DTIC Science & Technology

1975-07-01

supervisors and workers in a bogus greeting card company performed experimental tasks involving construction of " origami " cranes. The following variables...comprised of a supervisor and three workers who, in turn, were assigned the task of producing " origami " paper cranes and were paid on a piece-rate basis...behaviors as he inter- acted with his followers. Experimental Task The experimental task involved the construction of " origami " cranes from sheets of

Usefulness of FTIR spectroscopy to distinguish rough and smooth variants of Lactobacillus farciminis CNCM-I-3699.

PubMed

Tareb, R; Bernardeau, M; Amiel, C; Vernoux, J P

2017-02-01

In this study, the potential of Fourier transform infrared (FTIR) spectroscopy for assessing putative biochemical and structural differences between the two variants, rough (R) and smooth (S), of Lactobacillus farciminis CNCM-I-3699, a pleomorphic strain, was investigated. The main differences observed were localized in the polysaccharide (1200-900 cm-1) and protein (1700-1500 cm-1) regions. Based on spectral information in these two spectral ranges, clustering resulted in a dendrogram that showed a clear discrimination between both morphotypes. Significant increases in favor of morphotype S compared to R at specific wavenumbers for polysaccharides (22.18% vs. 5.24% at 1068 cm-1) and capsular polysaccharides (16% vs. 13.17% at 1048 cm-1) were recorded. Compared to S, the morphotype R exhibits a 1.27-fold higher signal at the wavenumber of 1637 cm-1 assigned to the amide I β-sheet and a 2.71-fold higher signal at the wavenumber of 1513 cm-1 assigned to the tyrosine involved in the β-sheet arrangement of proteins. The FTIR analysis is efficient to separate and give data on mainly surface component differences observed previously between S colony morphotype (ropy and exopolysaccharide positive) and the R colony morphotype (non-ropy but highly autoaggregative). © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Fuels planning: science synthesis and integration; social issues fact sheet 01: Developing personal responsibility for fuels reduction: Building a successful program to engage property owners

Treesearch

Rocky Mountain Research Station USDA Forest Service

2004-01-01

In the course of work as a land manager, you will no doubt be involved in developing programs to achieve various objectives, including the improvement of fuels management on private lands. This fact sheet describes six steps that will help you plan and conduct a successful program.

Facts on Grants, 1983. A Report on Grantmaking of the Charles Stewart Mott Foundation.

ERIC Educational Resources Information Center

Mott (C.S.) Foundation, Flint, MI.

Summaries of 349 grants made in 1983 by the Charles Stewart Mott Foundation are presented. The guide contains fact sheets on grants for $15,000 or above; all grants for amounts under $15,000 are listed with brief descriptions. Most of the fact sheets provide information on how grants meet the objectives of the foundation, what they might…

Achieving spectrum conservation for the minimum-span and minimum-order frequency assignment problems

NASA Technical Reports Server (NTRS)

Heyward, Ann O.

1992-01-01

Effective and efficient solutions of frequency assignment problems assumes increasing importance as the radiofrequency spectrum experiences ever increasing utilization by diverse communications services, requiring that the most efficient use of this resource be achieved. The research presented explores a general approach to the frequency assignment problem, in which such problems are categorized by the appropriate spectrum conserving objective function, and are each treated as an N-job, M-machine scheduling problem appropriate for the objective. Results obtained and presented illustrate that such an approach presents an effective means of achieving spectrum conserving frequency assignments for communications systems in a variety of environments.

Comparison of efficacy of silicone gel, silicone gel sheeting, and topical onion extract including heparin and allantoin for the treatment of postburn hypertrophic scars.

PubMed

Karagoz, Huseyin; Yuksel, Fuat; Ulkur, Ersin; Evinc, Rahmi

2009-12-01

We compared the efficacy of silicone gel (Scarfade), silicone gel sheet (Epi-Derm), and topical onion extract including heparin and allantoin (Contractubex) for the treatment of hypertrophic scars. Forty-five postburn scars were included in the study. Patients with scars less than 6 months from injury were assigned at random to three groups each containing 15 scars, and their treatment was continued for 6 months. Scars were treated with Scarfade, Epiderm and Contractubex. Scar assessment was performed at the beginning of the treatment, and at the end of the sixth month when the treatment was completed by using the Vancouver scar scale. The difference between before and after treatment scores for each three groups was statistically significant. The difference between Scarfade group and Epi-Derm group was not significant; however, the differences of the other groups (Scarfade-Contractubex, Epiderm-Contractubex) were significant. Silicone products, either in gel or sheet, are superior to Contractubex in the treatment of the hypertrophic scar. The therapist should select the most appropriate agent according to the patient's need and guidelines of these signs.

Characterization and optimization of flexible dual mode sensor based on Carbon Micro Coils

NASA Astrophysics Data System (ADS)

Dat Nguyen, Tien; Kim, Taeseung; Han, Hyoseung; Shin, Hyun Yeong; Nguyen, Canh Toan; Phung, Hoa; Ryeol Choi, Hyouk

2018-01-01

Carbon Microcoils (CMCs) is a 3D helical micro structure grown via a chemical vapor deposition process. It is noted that composites in which CMCs are embedded in polymer matrixes, called CMC sheets, experience a drastic change of electrical impedance depending on the proximity and contact of external objects. In this paper, a dual functional sensor, that is, tactile and proximity sensor fabricated with CMC/silicone composite is presented to demonstrate the advanced characteristics of CMCs sheets. Characteristics of sensor responses depending on CMC compositions are investigated and optimal conditions are determined. The candidates of polymer matrices are also investigated. As the results, the CMC sheet consisting of Ecoflex 30, CMC 30 {{wt}} % , and multiwall carbon nanotubes 1 {{wt}} % shows the most appropriate tactile sensing characteristics with more than 1 mm of thickness. The proximity sensing capability is the maximum when the 1.5 {{wt}} % CMC content is mixed with Dragon skin 30 silicone substrate. Finally, multiple target objects are recognized with the results and their feasibilities are experimentally validated.

Assessment of a Diversity Assignment in a PR Principles Course

ERIC Educational Resources Information Center

Gallicano, Tiffany Derville; Stansberry, Kathleen

2012-01-01

This study assesses an assignment for incorporating diversity into the principles of public relations course. The assignment is tailored to the challenges of using an active learning approach in a large lecture class. For the assignment, students write a goal, objectives, strategies, an identification of tactics, and evaluation plans for either…

Multi-objective optimization for model predictive control.

PubMed

Wojsznis, Willy; Mehta, Ashish; Wojsznis, Peter; Thiele, Dirk; Blevins, Terry

2007-06-01

This paper presents a technique of multi-objective optimization for Model Predictive Control (MPC) where the optimization has three levels of the objective function, in order of priority: handling constraints, maximizing economics, and maintaining control. The greatest weights are assigned dynamically to control or constraint variables that are predicted to be out of their limits. The weights assigned for economics have to out-weigh those assigned for control objectives. Control variables (CV) can be controlled at fixed targets or within one- or two-sided ranges around the targets. Manipulated Variables (MV) can have assigned targets too, which may be predefined values or current actual values. This MV functionality is extremely useful when economic objectives are not defined for some or all the MVs. To achieve this complex operation, handle process outputs predicted to go out of limits, and have a guaranteed solution for any condition, the technique makes use of the priority structure, penalties on slack variables, and redefinition of the constraint and control model. An engineering implementation of this approach is shown in the MPC embedded in an industrial control system. The optimization and control of a distillation column, the standard Shell heavy oil fractionator (HOF) problem, is adequately achieved with this MPC.

Increased alpha band activity indexes inhibitory competition across a border during figure assignment.

PubMed

Sanguinetti, Joseph L; Trujillo, Logan T; Schnyer, David M; Allen, John J B; Peterson, Mary A

2016-09-01

Figure-ground assignment is thought to entail inhibitory competition between potential objects on opposite sides of a shared border; the winner is perceived as the figure, and the loser as the shapeless ground. Computational models and response time measures support this understanding but to date no online measure of inhibitory competition during figure-ground assignment has been reported. The current study assays electroencephalogram (EEG) alpha power as a measure of inhibitory competition during figure-ground assignment. Activity in the EEG alpha band has been linked to functional inhibition in the brain, and it has been proposed that increased alpha power reflects increased inhibition. In 2 experiments participants viewed silhouettes designed so that the insides would be perceived as figures. Real-world silhouettes depicted namable objects. Novel silhouettes depicted novel objects on the insides of their borders, but varied in the amount of hypothesized cross-border competition for figural status: In "Low-Competition" silhouettes, the borders suggested novel objects on the outside as well as on the inside. In "High-Competition" silhouettes the borders suggested portions of real-world objects on the outside; these compete with the figural properties favoring the inside as figure. Participants accurately categorized both types of novel silhouettes as "novel" objects and were unaware of the real world objects suggested on the outside of the High-Competition silhouettes. In both experiments, we observed more alpha power while participants viewed High- rather than Low-Competition novel silhouettes. These are the first results to show via an online index of neural activity that figure assignment entails inhibitory competition. Copyright © 2015 Elsevier Ltd. All rights reserved.

SPED light sheet microscopy: fast mapping of biological system structure and function

PubMed Central

Tomer, Raju; Lovett-Barron, Matthew; Kauvar, Isaac; Andalman, Aaron; Burns, Vanessa M.; Sankaran, Sethuraman; Grosenick, Logan; Broxton, Michael; Yang, Samuel; Deisseroth, Karl

2016-01-01

The goal of understanding living nervous systems has driven interest in high-speed and large field-of-view volumetric imaging at cellular resolution. Light-sheet microscopy approaches have emerged for cellular-resolution functional brain imaging in small organisms such as larval zebrafish, but remain fundamentally limited in speed. Here we have developed SPED light sheet microscopy, which combines large volumetric field-of-view via an extended depth of field with the optical sectioning of light sheet microscopy, thereby eliminating the need to physically scan detection objectives for volumetric imaging. SPED enables scanning of thousands of volumes-per-second, limited only by camera acquisition rate, through the harnessing of optical mechanisms that normally result in unwanted spherical aberrations. We demonstrate capabilities of SPED microscopy by performing fast sub-cellular resolution imaging of CLARITY mouse brains and cellular-resolution volumetric Ca2+ imaging of entire zebrafish nervous systems. Together, SPED light sheet methods enable high-speed cellular-resolution volumetric mapping of biological system structure and function. PMID:26687363

The Great Balancing Act. Nutrition Comes Alive. Level 4. Nutrition Educator's Guide and Work Sheets, Information Sheets, Story, Letters to Parents. Revised Edition.

ERIC Educational Resources Information Center

Waldron, Laurie

This guide offers a nutrition education program for students in Kindergarten through Grade 6. Activities span all grades as well as activities for the specific level. Nutrition education objectives are stated for each grade level: (1) grade four--students will explore how to balance food intake and energy output for overall health and physical…

Dehydration of main-chain amides in the final folding step of single-chain monellin revealed by time-resolved infrared spectroscopy

PubMed Central

Kimura, Tetsunari; Maeda, Akio; Nishiguchi, Shingo; Ishimori, Koichiro; Morishima, Isao; Konno, Takashi; Goto, Yuji; Takahashi, Satoshi

2008-01-01

Kinetic IR spectroscopy was used to reveal β-sheet formation and water expulsion in the folding of single-chain monellin (SMN) composed of a five-stranded β-sheet and an α-helix. The time-resolved IR spectra between 100 μs and 10 s were analyzed based on two consecutive intermediates, I1 and I2, appearing within 100 μs and with a time constant of ≈100 ms, respectively. The initial unfolded state showed broad amide I′ corresponded to a fluctuating conformation. In contrast, I1 possessed a feature at 1,636 cm−1 for solvated helix and weak features assignable to turns, demonstrating the rapid formation of helix and turns. I2 possessed a line for solvated helix at 1,637 cm−1 and major and minor lines for β-sheet at 1,625 and 1,680 cm−1, respectively. The splitting of the major and minor lines is smaller than that of the native state, implying an incomplete formation of the β-sheet. Furthermore, both major and minor lines demonstrated a low-frequency shift compared to those of the native state, which was interpreted to be caused by hydration of the CO group in the β-sheet. Together with the identification of solvated helix, the core domain of I2 was interpreted as being hydrated. Finally, slow conversion of the water-penetrated core of I2 to the dehydrated core of the native state was observed. We propose that both the expulsion of water, hydrogen-bonded to main-chain amides, and the completion of the secondary structure formation contribute to the energetic barrier of the rate-limiting step in SMN folding. PMID:18757727

Interface between hospital and fire authorities--a concept for management of incidents in hospitals.

PubMed

Gretenkort, Peter; Harke, Henning; Blazejak, Jan; Pache, Bernd; Leledakis, Georgios

2002-01-01

Although every hospital needs a security plan for the support of immobile patients who do not possess autonomous escape capabilities, little information exists to assist in the development of practical patient evacuation methods. 1) In hospitals during disasters, incident leadership of the fire authorities can be supported effectively by hospital executives experienced in the management of mass casualties; and 2) As an alternative for canvas carry sheets, rescue drag sheets can be employed for emergency, elevator-independent, patient evacuation. A hospital evacuation exercise was planned and performed to obtain experiences in incident command and to permit calculation of elevator-independent patient transport times. Performance of incident leadership was observed by means of pre-defined checklists. The effectiveness and efficiency of carrying teams with five persons each were compared to those with a rescue drag sheet employed by a single person. Incident command for hospitals during a disaster is enhanced considerably by pre-defined and trained executives who are placed at the immediate disposal of the fire authorities. For elevator-independent patient transport, the rescue drag sheet was superior to conventional carrying measures because of a reduced number of transport personnel required to move each patient. With this method, patient transport times averaged 54 m/min. flat and 18 seconds for one floor descent. Experiences from a hospital during an evacuation exercise provided decision criteria for changes in the disaster preparedness plan. Hospital incident leadership was assigned to executives-in-charge in close co-operation with the fire authorities. All beds were equipped with a rescue drag sheet. Both concepts may help to cope with an emergency evacuation of a hospital.

Higher-order molecular packing in amyloid-like fibrils constructed with linear arrangements of hydrophobic and hydrogen-bonding side-chains.

PubMed

Saiki, Masatoshi; Honda, Shinya; Kawasaki, Kazunori; Zhou, Deshan; Kaito, Akira; Konakahara, Takeo; Morii, Hisayuki

2005-05-13

Various mutants of the protein fragment, barnase module-1 (1-24) were investigated in order to reveal the structural principle of amyloid-like fibrils. By means of circular dichroism spectroscopy, X-ray diffraction, electron microscopy, and thioflavin T binding assay, we found that the molecules containing two beta-strands and an intervening turn structure are assembled to form a cross-beta structure. Stabilization by both the hydrophobic interactions and hydrogen bonding between the respective paired side-chains on the coupled beta-strands was essential for fibril formation. These two types of interaction can also arrange the corresponding residues in lines on both sheet surfaces of protofilaments with a cross-beta structure. This leads to the most probable fibril structure constructed with the line-matching interactions between protofilaments. Consideration of the geometrical symmetry resulted in our finding that a limited number of essential models for molecular packing in fibril structure are stable, which would rationally explain the occurrence of two or three morphologies from an identical molecular species. The ribbon-like fibrils exhibited striped texture along the axis, which was assigned to a stacked two-sheet repeat as a structural unit. The comprehensively proposed structural model, that is, the sheet-sheet interaction between left-handed cross-beta structures, results in a slightly right-handed twist of beta-sheet stacking, which reasonably elucidates the intrinsic sizes of the fibril width and its helical period along the fibril axis, as the bias in the orientation of the hydrogen-bonded beta-strand pair at the lateral edge is larger than that at the central protofilament.

An efficient sequential approach to tracking multiple objects through crowds for real-time intelligent CCTV systems.

PubMed

Li, Liyuan; Huang, Weimin; Gu, Irene Yu-Hua; Luo, Ruijiang; Tian, Qi

2008-10-01

Efficiency and robustness are the two most important issues for multiobject tracking algorithms in real-time intelligent video surveillance systems. We propose a novel 2.5-D approach to real-time multiobject tracking in crowds, which is formulated as a maximum a posteriori estimation problem and is approximated through an assignment step and a location step. Observing that the occluding object is usually less affected by the occluded objects, sequential solutions for the assignment and the location are derived. A novel dominant color histogram (DCH) is proposed as an efficient object model. The DCH can be regarded as a generalized color histogram, where dominant colors are selected based on a given distance measure. Comparing with conventional color histograms, the DCH only requires a few color components (31 on average). Furthermore, our theoretical analysis and evaluation on real data have shown that DCHs are robust to illumination changes. Using the DCH, efficient implementations of sequential solutions for the assignment and location steps are proposed. The assignment step includes the estimation of the depth order for the objects in a dispersing group, one-by-one assignment, and feature exclusion from the group representation. The location step includes the depth-order estimation for the objects in a new group, the two-phase mean-shift location, and the exclusion of tracked objects from the new position in the group. Multiobject tracking results and evaluation from public data sets are presented. Experiments on image sequences captured from crowded public environments have shown good tracking results, where about 90% of the objects have been successfully tracked with the correct identification numbers by the proposed method. Our results and evaluation have indicated that the method is efficient and robust for tracking multiple objects (>or= 3) in complex occlusion for real-world surveillance scenarios.

Personalized disease-specific protein corona influences the therapeutic impact of graphene oxide

NASA Astrophysics Data System (ADS)

Hajipour, Mohammad Javad; Raheb, Jamshid; Akhavan, Omid; Arjmand, Sareh; Mashinchian, Omid; Rahman, Masoud; Abdolahad, Mohammad; Serpooshan, Vahid; Laurent, Sophie; Mahmoudi, Morteza

2015-05-01

The hard corona, the protein shell that is strongly attached to the surface of nano-objects in biological fluids, is recognized as the first layer that interacts with biological objects (e.g., cells and tissues). The decoration of the hard corona (i.e., the type, amount, and conformation of the attached proteins) can define the biological fate of the nanomaterial. Recent developments have revealed that corona decoration strongly depends on the type of disease in human patients from which the plasma is obtained as a protein source for corona formation (referred to as the `personalized protein corona'). In this study, we demonstrate that graphene oxide (GO) sheets can trigger different biological responses in the presence of coronas obtained from various types of diseases. GO sheets were incubated with plasma from human subjects with different diseases/conditions, including hypofibrinogenemia, blood cancer, thalassemia major, thalassemia minor, rheumatism, fauvism, hypercholesterolemia, diabetes, and pregnancy. Identical sheets coated with varying protein corona decorations exhibited significantly different cellular toxicity, apoptosis, and uptake, reactive oxygen species production, lipid peroxidation and nitrogen oxide levels. The results of this report will help researchers design efficient and safe, patient-specific nano biomaterials in a disease type-specific manner for clinical and biological applications.The hard corona, the protein shell that is strongly attached to the surface of nano-objects in biological fluids, is recognized as the first layer that interacts with biological objects (e.g., cells and tissues). The decoration of the hard corona (i.e., the type, amount, and conformation of the attached proteins) can define the biological fate of the nanomaterial. Recent developments have revealed that corona decoration strongly depends on the type of disease in human patients from which the plasma is obtained as a protein source for corona formation (referred to as the `personalized protein corona'). In this study, we demonstrate that graphene oxide (GO) sheets can trigger different biological responses in the presence of coronas obtained from various types of diseases. GO sheets were incubated with plasma from human subjects with different diseases/conditions, including hypofibrinogenemia, blood cancer, thalassemia major, thalassemia minor, rheumatism, fauvism, hypercholesterolemia, diabetes, and pregnancy. Identical sheets coated with varying protein corona decorations exhibited significantly different cellular toxicity, apoptosis, and uptake, reactive oxygen species production, lipid peroxidation and nitrogen oxide levels. The results of this report will help researchers design efficient and safe, patient-specific nano biomaterials in a disease type-specific manner for clinical and biological applications. Electronic supplementary information (ESI) available. See DOI: 10.1039/c5nr00520e

The Cryosphere Model Comparison Tool (CmCt): Ice Sheet Model Validation and Comparison Tool for Greenland and Antarctica

NASA Astrophysics Data System (ADS)

Simon, E.; Nowicki, S.; Neumann, T.; Tyahla, L.; Saba, J. L.; Guerber, J. R.; Bonin, J. A.; DiMarzio, J. P.

2017-12-01

The Cryosphere model Comparison tool (CmCt) is a web based ice sheet model validation tool that is being developed by NASA to facilitate direct comparison between observational data and various ice sheet models. The CmCt allows the user to take advantage of several decades worth of observations from Greenland and Antarctica. Currently, the CmCt can be used to compare ice sheet models provided by the user with remotely sensed satellite data from ICESat (Ice, Cloud, and land Elevation Satellite) laser altimetry, GRACE (Gravity Recovery and Climate Experiment) satellite, and radar altimetry (ERS-1, ERS-2, and Envisat). One or more models can be uploaded through the CmCt website and compared with observational data, or compared to each other or other models. The CmCt calculates statistics on the differences between the model and observations, and other quantitative and qualitative metrics, which can be used to evaluate the different model simulations against the observations. The qualitative metrics consist of a range of visual outputs and the quantitative metrics consist of several whole-ice-sheet scalar values that can be used to assign an overall score to a particular simulation. The comparison results from CmCt are useful in quantifying improvements within a specific model (or within a class of models) as a result of differences in model dynamics (e.g., shallow vs. higher-order dynamics approximations), model physics (e.g., representations of ice sheet rheological or basal processes), or model resolution (mesh resolution and/or changes in the spatial resolution of input datasets). The framework and metrics could also be used for use as a model-to-model intercomparison tool, simply by swapping outputs from another model as the observational datasets. Future versions of the tool will include comparisons with other datasets that are of interest to the modeling community, such as ice velocity, ice thickness, and surface mass balance.

Improving postoperative tonsillectomy pain management in children--a double blinded randomised control trial of a patient analgesia information sheet.

PubMed

Bailey, Lucas; Sun, Jing; Courtney, Mark; Murphy, Paul

2015-05-01

To evaluate paediatric post-tonsillectomy pain management using oxycodone when a specific analgesia information sheet is included with standard postoperative information. Oxycodone information sheets were randomly allocated to half the study children's post-tonsillectomy information pack. The trial was double-blinded to the surgeon, anaesthetist, nursing and administrative staff. Parents and children completed the pain assessment on day 3, 5 and 7. On day 10 the parents completed a questionnaire. A postoperative analgesia information sheet provides for higher satisfaction and knowledge for parents using oxycodone (p<0.001) and children have improved postoperative pain control, most significantly at day 5 (p<0.05). Parent assessment of the child's analgesia was superior with the oxycodone information sheet, most significantly at day 3 and 7 post operatively (p<0.05). There is also a positive correlation between the parents' observed pain score and children's self reported pain score, with a low correlation efficient level observed (p<0.001). Information sheets are useful in education and use of postoperative analgesia. The primary objective to explore the efficacy of the information sheet has proved to be successful in this setting. Given risks of opioid analgesia, it is recommended that postoperative information sheets be given to all parents, to provide for improved analgesia control and safe management of children in the postoperative period. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Use of Polypentapeptides of Elastin to Prevent Postoperative Adhesions: Efficacy in a Contaminated Peritoneal Model

DTIC Science & Technology

1994-02-01

short-gut syndrome, rotomy was conducted to reveal the cranial portion of chronic pain , and female infertility [3, 4]. Many sub- the ileum. The abdominal ...hold the sheets in the proper position. The presence of nal adhesions, chronic abdominal pain , and infertility. Gynecol. suture material acting as a...intra- abdominal landmarks. Opera- of 88 rats were studied with random assignment of ani- tions in this situation are often associated with mals to three

The GLAS Standard Data Products Specification--Level 2, Version 9. Volume 14

NASA Technical Reports Server (NTRS)

Lee, Jeffrey E.

2013-01-01

The Geoscience Laser Altimeter System (GLAS) is the primary instrument for the ICESat (Ice, Cloud and Land Elevation Satellite) laser altimetry mission. ICESat was the benchmark Earth Observing System (EOS) mission for measuring ice sheet mass balance, cloud and aerosol heights, as well as land topography and vegetation characteristics. From 2003 to 2009, the ICESat mission provided multi-year elevation data needed to determine ice sheet mass balance as well as cloud property information, especially for stratospheric clouds common over polar areas. It also provided topography and vegetation data around the globe, in addition to the polar-specific coverage over the Greenland and Antarctic ice sheets.This document defines the Level-2 GLAS standard data products. This document addresses the data flow, interfaces, record and data formats associated with the GLAS Level 2 standard data products. The term standard data products refers to those EOS instrument data that are routinely generated for public distribution. The National Snow and Ice Data Center (NSDIC) distribute these products. Each data product has a unique Product Identification code assigned by the Senior Project Scientist. The Level 2 Standard Data Products specifically include those derived geophysical data values (i.e., ice sheet elevation, cloud height, vegetation height, etc.). Additionally, the appropriate correction elements used to transform the Level 1A and Level 1B Data Products into Level 2 Data Products are included. The data are packaged with time tags, precision orbit location coordinates, and data quality and usage flags.

A pilot study of simple interventions to improve informed consent in clinical research: feasibility, approach, and results.

PubMed

Kass, Nancy E; Taylor, Holly A; Ali, Joseph; Hallez, Kristina; Chaisson, Lelia

2015-02-01

Research suggests that participants do not always adequately understand studies. While some consent interventions increase understanding, methodologic challenges have been raised in studying consent outside of actual trial settings. This study examined the feasibility of testing two consent interventions in actual studies and measured effectiveness of interventions in improving understanding. Participants enrolling in any of eight ongoing clinical trials were sequentially assigned to one of three different informed consent strategies for enrollment in their clinical trial. Control participants received standard consent procedures for their trial. Participants in the first intervention arm received a bulleted fact sheet summarizing key study information. Participants in the second intervention arm received the bulleted fact sheet and also engaged in a feedback Q&A session. Later, patients answered closed- and open-ended questions to assess patient understanding and literacy. Descriptive statistics, Wilcoxon -Mann -Whitney and Kruskal-Wallis tests were generated to assess correlations; regression analysis determined predictors of understanding. 144 participants enrolled. Using regression analysis, participants receiving the second intervention scored 7.6 percentage points higher (p = .02) on open-ended questions about understanding than participants in the control, although unadjusted comparisons did not reach statistical significance. Our study supports the hypothesis that patients receiving both bulleted fact sheets and a Q&A session had higher understanding compared to standard consent. Fact sheets and short structured dialog are quick to administer and easy to replicate across studies and should be tested in larger samples. © The Author(s) 2014.

Carpentry. Student Learning Guide.

ERIC Educational Resources Information Center

Palm Beach County Board of Public Instruction, West Palm Beach, FL.

This student learning guide contains 17 modules for completing a course in carpentry. It is designed especially for use in secondary schools in Palm Beach County, Florida. Each module covers one task, and consists of a purpose, performance objective, enabling objectives, learning activities keyed to resources, information sheets, student…

Masonry. Student Learning Guide.

ERIC Educational Resources Information Center

Palm Beach County Board of Public Instruction, West Palm Beach, FL.

This student learning guide contains nine modules for completing a course in masonry. It is designed especially for use in secondary schools in Palm Beach County, Florida. Each module covers one task, and consists of a purpose, performance objective, enabling objectives, learning activities keyed to resources, information sheets, student…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Driscoll, P.C.; Clore, G.M.; Beress, L.

The sequential resonance assignment of the {sup 1}H NMR spectrum of the antihypertensive and antiviral protein BDS-I from the sea anemone Anemonia sulcata is presented. This is carried out with two-dimensional NMR techniques to identify through-bond and through-space (< 5{angstrom}) connectivities. Added spectral complexity arises from the fact that the sample is an approximately 1:1 mixture of two BDS-I isoproteins, (Leu-18)-BDS-I and (Phe-18)-BDS-I. Complete assignments, however, are obtained, largely due to the increased resolution and sensitivity afforded at 600 MHz. In addition, the stereospecific assignment of a large number of {beta}-methylene protons is achieved from an analysis of the patternmore » of {sup 3}J{sub {alpha}{beta}} coupling constants and the relative magnitudes of intraresidue NOEs involving the NH, C{sup {alpha}}H, and C{sup {beta}}H protons. Regular secondary structure elements are deduced from a qualitative interpretation of the nuclear Overhauser enhancement, {sup 3}J{sub HN{alpha}} coupling constant, and amide NH exchange data. A triple-stranded antiparallel {beta}-sheet is found to be related to that found in partially homologous sea anemone polypeptide toxins.« less

Multi objective Taguchi optimization approach for resistance spot welding of cold rolled TWIP steel sheets

NASA Astrophysics Data System (ADS)

Tutar, Mumin; Aydin, Hakan; Bayram, Ali

2017-08-01

Formability and energy absorption capability of a steel sheet are highly desirable properties in manufacturing components for automotive applications. TWinning Induced Plastisity (TWIP) steels are, new generation high Mn alloyed steels, attractive for the automotive industry due to its outstanding elongation (%40-45) and tensile strength (~1000MPa). So, TWIP steels provide excellent formability and energy absorption capability. Another required property from the steel sheets is suitability for manufacturing methods such as welding. The use of the steel sheets in the automotive applications inevitably involves welding. Considering that there are 3000-5000 welded spots on a vehicle, it can be interpreted that one of the most important manufacturing method is Resistance Spot Welding (RSW) for the automotive industry. In this study; firstly, TWIP steel sheet were cold rolled to 15% reduction in thickness. Then, the cold rolled TWIP steel sheets were welded with RSW method. The welding parameters (welding current, welding time and electrode force) were optimized for maximizing the peak tensile shear load and minimizing the indentation of the joints using a Taguchi L9 orthogonal array. The effect of welding parameters was also evaluated by examining the signal-to-noise ratio and analysis of variance (ANOVA) results.

Superplastic Forming/Adhesive Bonding of Aluminum (SPF/AB) Multi-Sheet Structures

NASA Technical Reports Server (NTRS)

Wagner, John A. (Technical Monitor); Will, Jeff D.; Cotton, James D.

2003-01-01

A significant fraction of airframe structure consists of stiffened panels that are costly and difficult to fabricate. This program explored a potentially lower-cost processing route for producing such panels. The alternative process sought to apply concurrent superplastic forming and adhesive bonding of aluminum alloy sheets. Processing conditions were chosen to balance adequate superplasticity of the alloy with thermal stability of the adhesive. As a first objective, an air-quenchable, superplastic aluminum-lithium alloy and a low-volatile content, low-viscosity adhesive with compatible forming/curing cycles were identified. A four-sheet forming pack was assembled which consisted of a welded two-sheet core separated from the face sheets by a layer of adhesive. Despite some preliminary success, of over 30 forming trials none was completely successful. The main problem was inadequate superplasticity in the heat-affected zones of the rib welds, which generally fractured prior to completion of the forming cycle. The welds are a necessary component in producing internal ribs by the 'four-sheet' process. Other challenges, such as surface preparation and adhesive bonding, were adequately solved. But without the larger issue of tearing at the weld locations, complex panel fabrication by SPF/AB does not appear viable.

Effect of the material properties on the crumpling of a thin sheet.

PubMed

Habibi, Mehdi; Adda-Bedia, Mokhtar; Bonn, Daniel

2017-06-07

While simple at first glance, the dense packing of sheets is a complex phenomenon that depends on material parameters and the packing protocol. We study the effect of plasticity on the crumpling of sheets of different materials by performing isotropic compaction experiments on sheets of different sizes and elasto-plastic properties. First, we quantify the material properties using a dimensionless foldability index. Then, the compaction force required to crumple a sheet into a ball as well as the average number of layers inside the ball are measured. For each material, both quantities exhibit a power-law dependence on the diameter of the crumpled ball. We experimentally establish the power-law exponents and find that both depend nonlinearly on the foldability index. However the exponents that characterize the mechanical response and morphology of the crumpled materials are related linearly. A simple scaling argument explains this in terms of the buckling of the sheets, and recovers the relation between the crumpling force and the morphology of the crumpled structure. Our results suggest a new approach to tailor the mechanical response of the crumpled objects by carefully selecting their material properties.

Low-cost solar array project progress and plans

NASA Technical Reports Server (NTRS)

Callaghan, W. T.

1981-01-01

The considered project is part of the DOE Photovoltaic Technology and Market Development Program. This program is concerned with the development and the utilization of cost-competitive photovoltaic systems. The project has the objective to develop, by 1986, the national capability to manufacture low-cost, long-life photovoltaic arrays at production rates that will realize economies of scale, and at a price of less than $0.70/watt. The array performance objectives include an efficiency greater than 10% and an operating lifetime longer than 20 years. The objective of the silicon material task is to establish the practicality of processes for producing silicon suitable for terrestrial photovoltaic applications at a price of $14/kg. The large-area sheet task is concerned with the development of process technology for sheet formation. Low-cost encapsulation material systems are being developed in connection with the encapsulation task. Another project goal is related to the development of economical process sequences.

Self-Contained Math Manual. Teacher's Guide.

ERIC Educational Resources Information Center

Grant, Shelia I.

This instructional manual consists of 11 competency-based units for a mathematics course for trade and industrial programs in Texas. Each instructional unit includes the following basic components: unit and specific objectives, notes to the instructor (outline of steps to follow in accomplishing specific objectives), information sheets,…

Welding. Student Learning Guide.

ERIC Educational Resources Information Center

Palm Beach County Board of Public Instruction, West Palm Beach, FL.

This student learning guide contains 30 modules for completing a course in welding. It is designed especially for use in secondary schools in Palm Beach County, Florida. Each module covers one task, and consists of a purpose, performance objective, enabling objectives, learning activities keyed to resources, information sheets, student self-check…

Research on NC laser combined cutting optimization model of sheet metal parts

NASA Astrophysics Data System (ADS)

Wu, Z. Y.; Zhang, Y. L.; Li, L.; Wu, L. H.; Liu, N. B.

2017-09-01

The optimization problem for NC laser combined cutting of sheet metal parts was taken as the research object in this paper. The problem included two contents: combined packing optimization and combined cutting path optimization. In the problem of combined packing optimization, the method of “genetic algorithm + gravity center NFP + geometric transformation” was used to optimize the packing of sheet metal parts. In the problem of combined cutting path optimization, the mathematical model of cutting path optimization was established based on the parts cutting constraint rules of internal contour priority and cross cutting. The model played an important role in the optimization calculation of NC laser combined cutting.

High-efficiency cell concepts on low-cost silicon sheets

NASA Technical Reports Server (NTRS)

Bell, R. O.; Ravi, K. V.

1985-01-01

The limitations on sheet growth material in terms of the defect structure and minority carrier lifetime are discussed. The effect of various defects on performance are estimated. Given these limitations designs for a sheet growth cell that will make the best of the material characteristics are proposed. Achievement of optimum synergy between base material quality and device processing variables is proposed. A strong coupling exists between material quality and the variables during crystal growth, and device processing variables. Two objectives are outlined: (1) optimization of the coupling for maximum performance at minimal cost; and (2) decoupling of materials from processing by improvement in base material quality to make it less sensitive to processing variables.

PRODUCTION OF SHEET FROM PARTICULATE MATERIAL

DOEpatents

Blainey, A.

1959-05-12

A process is presented for forming coherent sheet material from particulate material such as granular or powdered metal, granular or powdered oxide, slurries, pastes, and plastic mixes which cohere under pressure. The primary object is to avoid the use of expensive and/ or short lived pressing tools, that is, dies and specially profiled rolls, and so to reduce the cost of the product and to prcvide in a simple manner for the making of the product in a variety of shapes or sizes. The sheet material is formed when the particulate material is laterally confined in a boundary material deformable in all lateral directions under axial pressure and then axially compressing the layer of particulate material together with the boundary material.

Glacial dynamics (glaciology)

NASA Technical Reports Server (NTRS)

Whillans, Ian

1991-01-01

Recent results are reviewed from studies of ice dynamics that relate to the objectives of the West Antarctic Ice Sheet initiative. The large amount of knowledge gained is emphasized. The best evidence shows that the ice sheet in West Antarctic is the most rapidly changing ice sheet on earth today. Its rate of change is much faster than most glaciologists had expected and it is changing in a manner much more complex than foreseen. It appears that the changes have two broad causes: a delayed but ongoing response to the termination of the last glaciation about 10,000 years ago; and automatic, internally caused flow adjustments. It is not fully known why the response to the last global termination is so delayed, nor is the operation of internal instabilities understood, and certainly the position has not yet been attained to predict the future course of the evolution of the ice sheet.

Effects of electric current on individual graphene oxide sheets combining in situ transmission electron microscopy and Raman spectroscopy

NASA Astrophysics Data System (ADS)

Martín, Gemma; Varea, Aïda; Cirera, Albert; Estradé, Sònia; Peiró, Francesca; Cornet, Albert

2018-07-01

Graphene oxide (GO) is currently the object of extensive research because of its potential use in mass production of graphene-based materials, but also due to its tunability which holds great promise for new nanoscale electronic devices and sensors. To obtain a better understanding of the role of GO in electronic nano-devices, the elucidation of the effects of electrical current on a single GO sheet is of great interest. In this work, in situ transmission electron microscopy is used to study the effects of the electrical current flow through single GO sheets using an scanning tunneling microscope holder. In order to correlate the applied current with the structural properties of GO, Raman spectroscopy is carried out and data analysis is used to obtain information regarding the reduction grade and the disorder degree of the GO sheets before and after the application of current.

Effects of electric current on individual graphene oxide sheets combining in situ transmission electron microscopy and Raman spectroscopy.

PubMed

Martín, Gemma; Varea, Aïda; Cirera, Albert; Estradé, Sònia; Peiró, Francesca; Cornet, Albert

2018-04-17

Graphene oxide (GO) is currently the object of extensive research because of its potential use in mass production of graphene-based materials, but also due to its tunability which holds great promise for new nanoscale electronic devices and sensors. To obtain a better understanding of the role of GO in electronic nano-devices, the elucidation of the effects of electrical current on a single GO sheet is of great interest. In this work, in situ transmission electron microscopy is used to study the effects of the electrical current flow through single GO sheets using an scanning tunneling microscope holder. In order to correlate the applied current with the structural properties of GO, Raman spectroscopy is carried out and data analysis is used to obtain information regarding the reduction grade and the disorder degree of the GO sheets before and after the application of current.

Use of proline mutants to help solve the NMR solution structure of type III antifreeze protein.

PubMed Central

Chao, H.; Davies, P. L.; Sykes, B. D.; Sönnichsen, F. D.

1993-01-01

To help understand the structure/function relationships in antifreeze proteins (AFP), and to define the motifs required for ice binding, a Type III AFP suitable for two-dimensional (2D) NMR studies was produced in Escherichia coli. A synthetic gene for one of the Type III AFP isoforms was assembled in a T7 polymerase-directed expression vector. The 67-amino acid-long gene product differed from the natural AFP by inclusion of an N-terminal methionine but was indistinguishable in activity. The NMR spectra of this AFP were complicated by cis-trans proline isomerization from the C-terminal sequence YPPA. Substitution of this sequence by YAA eliminated isomer signals without altering the activity or structure of the mutant AFP. This variant (rQAE m1.1) was selected for sequential assignment and the secondary structure determination using 2D 1H NMR spectroscopy. Nine beta-strands are paired to form two triple-stranded antiparallel sheets and one double-stranded antiparallel sheet. Two further proline replacements, P29A and P33A, were made to delineate the role of conserved prolines in Type III AFP. These mutants were valuable in clarifying ambiguous NMR spectral assignments amongst the remaining six prolines of rQAE m1.1. In contrast to the replacement of the C-terminal prolyl residues, the exchange of P29 and P33 caused some structural changes and significantly decreased protein solubility and antifreeze activity. PMID:8401227

Electrophysiological Evidence for Use of the Animacy Hierarchy, but not Thematic Role Assignment, During Verb Argument Processing

PubMed Central

Paczynski, Martin; Kuperberg, Gina R.

2011-01-01

Animacy is known to play an important role in language processing and production, but debate remains as to how it exerts its effects: 1) through links to syntactic ordering, 2) through inherent differences between animate and inanimate entities in their salience/lexico-semantic accessibility, 3) through links to specific thematic roles. We contrasted these three accounts in two event related potential (ERP) experiments examining the processing of direct object arguments in simple English sentences. In Experiment 1, we found a larger N400 to animate than inanimate direct object arguments assigned the Patient role, ruling out the second account. In Experiment 2 we found no difference in the N400 evoked by animate direct object arguments assigned the Patient role (prototypically inanimate) and those assigned the Experiencer role (prototypically animate), ruling out the third account. We therefore suggest that animacy may impact processing through a direct link to syntactic linear ordering, at least on post-verbal arguments in English. We also examined processing on direct object arguments that violated the animacy-based selection restriction constraints of their preceding verbs. These violations evoked a robust P600, which was not modulated by thematic role assignment or reversibility, suggesting that the so-called semantic P600 is driven by overall propositional impossibility, rather than thematic role reanalysis. PMID:22199415

Communication and social competencies in medical education in German-speaking countries: the Basel consensus statement. Results of a Delphi survey.

PubMed

Kiessling, Claudia; Dieterich, Anja; Fabry, Götz; Hölzer, Henrike; Langewitz, Wolf; Mühlinghaus, Isabel; Pruskil, Susanne; Scheffer, Simone; Schubert, Sebastian

2010-11-01

To propose a comprehensive set of competencies and educational objectives for communication and social competencies in undergraduate medical education and to support the nationwide implementation of these issues in all medical schools. Thirty experts from different medical and psychosocial disciplines participated in a 2-day workshop using the Nominal Group Technique (NGT) to develop an initial set of educational objectives. These were refined, structured, and rated according to their importance by means of a two-step Delphi Survey involving additional experts in medical education. The initial workshop resulted in 188 educational objectives assigned to 26 different topics. After the Delphi Survey, 131 objectives remained, assigned to 19 different topics. Some objectives that could be assigned to more than one topic were subsumed under a new more general category. The described consensus process proved successful as one method to develop a set of educational objectives. The Basel consensus statement can be used to orientate curriculum reform and development in medical education. Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.

Finite Element Modeling and Analysis of Mars Entry Aeroshell Baseline Concept

NASA Technical Reports Server (NTRS)

Ahmed, Samee W.; Lane, Brittney M.

2017-01-01

The structure that is developed and analyzed in this project must be able to survive all the various load conditions that it will encounter along its course to Mars with the minimal amount of weight and material. At this stage, the goal is to study the capability of the structure using a finite element model (FEM). This FEM is created using a python script, and is numerically solved in Nastran. The purpose of the model is to achieve an optimization of mass given specific constraints on launch and entry. The generation and analysis of the baseline Rigid Mid-Range Lift to Drag Ratio Aeroshell model is a continuation and an improvement on previous work done for the FEM. The model is generated using Python programming with the axisymmetric placement of nodes for beam and shell elements. The shells are assigned a honeycomb sandwich material with an aluminum honeycomb core and composite face sheets, and the beams are assigned the same material as the shell face sheets. There are two load cases assigned to the model: Earth launch and Mars entry. The Earth launch case consists of pressure, gravity, and vibration loads, and the Mars entry case consists of just pressure and gravity loads. The Earth launch case was determined to be the driving case, though the analyses are performed for both cases to ensure the constraints are satisfied. The types of analysis performed with the model are design optimization, statics, buckling, normal modes, and frequency response, the last of which is only for the Earth launch load case. The final results indicated that all of the requirements are satisfied except the thermal limits, which could not yet be tested, and the normal modes for the Mars entry. However, the frequency limits during Mars entry are expected to be much higher than the lower frequency limits set for the analysis. In addition, there are still improvements that can be made in order to reduce the weight while still meeting all requirements.

Principles of Technology, Units 1-7. Curriculum Guide.

ERIC Educational Resources Information Center

Campbell, Robert, Comp.

This Idaho secondary education curriculum guide provides lists of tasks, performance objectives, and enabling objectives for instruction intended to impart entry-level employment skills in industrial technology. The first list is a general job competencies task profile, followed by a sheet on which teachers can evaluate students' general job…

Farm Business Management. Volume I. Vocational Agriculture Education.

ERIC Educational Resources Information Center

Hodgens, Jim; Meyers, Leland

This curriculum guide provides a basic core of instruction for the first year of a three-year adult program in farm business management. It contains 12 units of instruction. Each unit consists of seven basic components: performance objectives, teacher activities, information sheets (content essential for meeting the cognitive objectives),…

Machine Shop. Student Learning Guide.

ERIC Educational Resources Information Center

Palm Beach County Board of Public Instruction, West Palm Beach, FL.

This student learning guide contains eight modules for completing a course in machine shop. It is designed especially for use in Palm Beach County, Florida. Each module covers one task, and consists of a purpose, performance objective, enabling objectives, learning activities and resources, information sheets, student self-check with answer key,…

Film holder for radiographing tubing

DOEpatents

Davis, Earl V.; Foster, Billy E.

1976-01-01

A film cassette is provided which may be easily placed about tubing or piping and readily held in place while radiographic inspection is performed. A pair of precurved light-impervious semi-rigid plastic sheets, hinged at one edge, enclose sheet film together with any metallic foils or screens. Other edges are made light-tight with removable caps, and the entire unit is held securely about the object to be radiographed with a releasable fastener such as a strip of Velcro.

A Module Experimental Process System Development Unit (MEPSDU)

NASA Technical Reports Server (NTRS)

1982-01-01

Restructuring research objectives from a technical readiness demonstration program to an investigation of high risk, high payoff activities associated with producing photovoltaic modules using non-CZ sheet material is reported. Deletion of the module frame in favor of a frameless design, and modification in cell series parallel electrical interconnect configuration are reviewed. A baseline process sequence was identified for the fabrication of modules using the selected dendritic web sheet material, and economic evaluations of the sequence were completed.

Spectroscopic studies on the conformational transitions of a bovine growth hormone releasing factor analog

NASA Astrophysics Data System (ADS)

Sarver, Ronald W.; Friedman, Alan R.; Thamann, Thomas J.

1997-10-01

The secondary structure of the bovine growth hormone releasing factor analog, [Ile 2, Ser 8,28, Ala 15, Leu 27, Hse 30] bGRF(1-30)-NH-Ethyl, acetate salt (U-90699F) was studied in solution by Fourier transform infrared and Raman spectroscopies. Spectroscopic studies revealed that concentrated aqueous solutions of U-90699F (100 mg ml -1) undergo a secondary structure transition from disordered coil/α-helix to intermolecular β-sheet. Disordered coil and α-helical structure were grouped together in the infrared and Raman studies since the amide I vibrations are close in frequency and overlap in assignments was possible. Before the conformational transition, the facile exchange of the peptide's amide hydrogens for deuterium indicated that the majority of amide hydrogens were readily accessible to solvent. The kinetics of the conformational transition coincided with an increase in solution viscosity and turbidity. An initiation phase preceded the conformational transition during which only minor spectral changes were observed by infrared spectroscopy. The initiation phase and reaction kinetics were consistent with a highly cooperative nucleation ultimately leading to a network of intermolecular β-sheet structure and gel formation. Increased temperature accelerated the conformational transition. The conformational transition was thermally irreversible but the β-sheet structure of aggregated or gelled peptide could be disrupted by dilution and agitation.

Image Classification of Ribbed Smoked Sheet using Learning Vector Quantization

NASA Astrophysics Data System (ADS)

Rahmat, R. F.; Pulungan, A. F.; Faza, S.; Budiarto, R.

2017-01-01

Natural rubber is an important export commodity in Indonesia, which can be a major contributor to national economic development. One type of rubber used as rubber material exports is Ribbed Smoked Sheet (RSS). The quantity of RSS exports depends on the quality of RSS. RSS rubber quality has been assigned in SNI 06-001-1987 and the International Standards of Quality and Packing for Natural Rubber Grades (The Green Book). The determination of RSS quality is also known as the sorting process. In the rubber factones, the sorting process is still done manually by looking and detecting at the levels of air bubbles on the surface of the rubber sheet by naked eyes so that the result is subjective and not so good. Therefore, a method is required to classify RSS rubber automatically and precisely. We propose some image processing techniques for the pre-processing, zoning method for feature extraction and Learning Vector Quantization (LVQ) method for classifying RSS rubber into two grades, namely RSS1 and RSS3. We used 120 RSS images as training dataset and 60 RSS images as testing dataset. The result shows that our proposed method can give 89% of accuracy and the best perform epoch is in the fifteenth epoch.

[Developing patient information sheets in general practice. Proposal for a methodology].

PubMed

Sustersic, Mélanie; Meneau, Aurélia; Drémont, Roger; Paris, Adeline; Laborde, Laurent; Bosson, Jean-Luc

2008-12-15

Health information is patients' wish and right. For general practitioners, it is a duty, a legal obligation and a pre-requisite in any preventive approach. Written information must complete oral information since it improves health care quality. However, in general practice, there are no patient documents which are scientifically valid, understandable and efficient in terms of communication. To develop a method for creating patient information sheets and to experiment its feasibility through the development of 125 sheets focused on the most common clinical conditions in general practice. Research and literature review pour the development of specifications, and creation of 125 sheets following these specifications. The specifications developed consist of the 10 following steps: selection of the topic and the objectives, literature review, selection of the sections, drafting, validation of the scientific contents, assessment among patients, validation of the layout, selection of the media, delivery to patients and update. Following these specifications, we developed 125 information sheets. Each of these was reviewed by several physicians and assessed with R. Flesh readability test (the established acceptable threshold value was 40). The 30 sheets associated with the lowest scores were selected and reviewed to improve their overall readability. Even though some difficulties cannot be avoided when developing patient information sheets, each physician or physician association can create its own documents following the proposed specifications and thus deliver a customized message.

IGLOO: an Intermediate Complexity Framework to Simulate Greenland Ice-Ocean Interactions

NASA Astrophysics Data System (ADS)

Perrette, M.; Calov, R.; Beckmann, J.; Alexander, D.; Beyer, S.; Ganopolski, A.

2017-12-01

The Greenland ice-sheet is a major contributor to current and future sea level rise associated to climate warming. It is widely believed that over a century time scale, surface melting is the main driver of Greenland ice volume change, in contrast to melting by the ocean. It is due to relatively warmer air and less ice area exposed to melting by ocean water compared to Antarctica, its southern, larger twin. Yet most modeling studies do not have adequate grid resolution to represent fine-scale outlet glaciers and fjords at the margin of the ice sheet, where ice-ocean interaction occurs, and must use rather crude parameterizations to represent this process. Additionally, the ice-sheet area grounded below sea level has been reassessed upwards in the most recent estimates of bedrock elevation under the Greenland ice sheet, revealing a larger potential for marine-mediated melting than previously thought. In this work, we develop an original approach to estimate potential Greenland ice sheet contribution to sea level rise from ocean melting, in an intermediate complexity framework, IGLOO. We use a medium-resolution (5km) ice-sheet model coupled interactively to a number of 1-D flowline models for the individual outlet glaciers. We propose a semi-objective methodology to derive 1-D glacier geometries from 2-D Greenland datasets, as well as preliminary results of coupled ice-sheet-glaciers simulations with IGLOO.

Two-dimensional sup 1 H NMR studies on HPr protein from Staphylococcus aureus: Complete sequential assignments and secondary structure

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kalbitzer, H.R.; Neidig, K.P.; Hengstenberg, W.

1991-11-19

Complete sequence-specific assignments of the {sup 1}H NMR spectrum of HPr protein from Staphylococcus aureus were obtained by two-dimensional NMR methods. Important secondary structure elements that can be derived from the observed nuclear Overhauser effects are a large antiparallel {beta}-pleated sheet consisting of four strands, A, B, C, D, a segment S{sub AB} consisting of an extended region around the active-center histidine (His-15) and an {alpha}-helix, a half-turn between strands B and C, a segment S{sub CD} which shows no typical secondary structure, and the {alpha}-helical, C-terminal segment S{sub term}. These general structural features are similar to those found earliermore » in HPr proteins from different microorganisms such as Escherichia coli, Bacillus subtilis, and Streptococcus faecalis.« less

Teaching Theory in Occupational Therapy Using a Cooperative Learning: A Mixed-Methods Study.

PubMed

Howe, Tsu-Hsin; Sheu, Ching-Fan; Hinojosa, Jim

2018-01-01

Cooperative learning provides an important vehicle for active learning, as knowledge is socially constructed through interaction with others. This study investigated the effect of cooperative learning on occupational therapy (OT) theory knowledge attainment in professional-level OT students in a classroom environment. Using a pre- and post-test group design, 24 first-year, entry-level OT students participated while taking a theory course in their second semester of the program. Cooperative learning methods were implemented via in-class group assignments. The students were asked to complete two questionnaires regarding their attitudes toward group environments and their perception toward group learning before and after the semester. MANCOVA was used to examine changes in attitudes and perceived learning among groups. Students' summary sheets for each in-class assignment and course evaluations were collected for content analysis. Results indicated significant changes in students' attitude toward working in small groups regardless of their prior group experience.

Conversion of finished leather waste incorporated with plant fibers into value added consumer products - An effort to minimize solid waste in Ethiopia.

PubMed

Teklay, A; Gebeyehu, G; Getachew, T; Yaynshet, T; Sastry, T P

2017-10-01

Presently, the leftovers from leather product industries are discarded as waste in Ethiopia. The objective of the present study was therefore, to prepare composite sheets by incorporating various plant fibers like enset (Ensete ventricosum), hibiscus (Hibiscus cannabinus), jute (Corchorus trilocularis L.), palm (Phoenix dactylifera) and sisal (Agave sisal) in various proportions into the leather waste. Resin binder (RB) and natural rubber latex (NRL) were used as binding agents for the preparation of the composite sheets. The composite sheets prepared were characterized for their physicochemical properties (tensile strength, elongation at break, stitch tear strength, water absorption, water desorption and flexing strength). Composite sheets prepared using RB having 10% hibiscus, 20% palm and 40% sisal fibers showed better mechanical properties than their respective controls. In composite sheets prepared using NRL having 30% jute fiber exhibited better mechanical properties than its control. Most of the plant fibers used in this study played a role in increasing the performance of the sheets. However, as seen from the results, the contribution of these plant fibers on performance of the composite sheets prepared is dependent on the ratio used and the nature of binder. The SEM studies have exhibited the composite nature of the sheets and FTIR studies have shown the functional groups of collagen protein, cellulose and binders. The prepared sheets were used as raw materials for preparation of items like stiff hand bags, ladies' purse, keychain, chappal upper, wallet, wall cover, mouse pad and other interior decorating products. By preparing such value added products, we can reduce solid waste; minimize environmental pollution and thereby securing environmental sustainability. Copyright © 2017 Elsevier Ltd. All rights reserved.

Selected DOE headquarters publications

DOE Office of Scientific and Technical Information (OSTI.GOV)

None

1979-07-01

Selected DOE Headquarters Publications provides cumulative listings, from October 1, 1977 onward, of two groups of publications issued by headquarters organizations of the Department of Energy, and an index to their title keywords. The two groups consist of publications assigned a DOE/XXX-type report number code and headquarters contractor publications, prepared by contractors (and published by DOE) to describe research and development work they have performed for the Department. Publications such as pamphlets, fact sheets, bulletins, newsletters, and telephone directories, are omitted, as are publications issued under the DOE-tr, CONF, DOE/JPL, and DOE/NASA codes. (RWR)

Archive of post-Hurricane Charley coastal oblique aerial photographs collected during U.S. Geological Survey field activity 04CCH01 from Marco Island to Fort DeSoto, Florida, August 15, 2004

USGS Publications Warehouse

Subino, Janice A.; Morgan, Karen L.M.; Krohn, M. Dennis; Miller, Gregory K.; Dadisman, Shawn V.; Forde, Arnell S.

2012-01-01

To view the survey maps and navigation files, and for more information about these items, see the Navigation page. Figure 1 displays the acquisition geometry. The tables provide detailed information about the assigned location, name, data, and time the photograph was taken along with links to the photo and corresponding 5-min contact sheet. Refer to table 1 and table 2 for details of the northern and southern county photographs, respectively.

Use of an appendicitis medical information sheet in the pediatric primary care system.

PubMed

Oyachi, Noboru; Yagasaki, Hideaki; Suzuki, Takeyuki; Higashida, Kosuke; Komai, Takayuki; Hasuda, Norio; Takano, Kunio; Obana, Kazuko

2016-10-01

Accurate and prompt diagnosis is required for the primary evaluation of pediatric appendicitis. Among pediatricians and surgeons working in Yamanashi Prefecture, the pediatric appendicitis medical information (PAMI) sheet was edited in April 2011 to reflect the diagnostic results of the pediatric primary and emergency medical service and used as a referral document for surgical consultation to secondary hospitals. The PAMI sheet consisted of sections for history taking, symptoms, physical signs and laboratory findings without a scoring system. For 32 consecutive months starting in April 2011, 59 patients hospitalized for suspected appendicitis were retrospectively reviewed. In particular, a total of 17 referral patients evaluated with the PAMI sheet were assessed in order to evaluate the utility of the form. The pediatric surgeons were able to easily determine patient condition from the PAMI sheet. In total, 13 of 17 patients had appendicitis. According to the physical findings of the 17 studied patients, the judgment of right lower quadrant tenderness (κ = 0.63) and guarding (κ = 1.00) was consistent between the pediatric surgeons and primary attending pediatricians. The PAMI sheet aids in the collection of detailed history and objective data with a high level of accuracy, and provides useful referral diagnostic information to the secondary-level hospitals. © 2016 Japan Pediatric Society.

Imaging galectin-3 dependent endocytosis with lattice light-sheet microscopy

NASA Astrophysics Data System (ADS)

Baek, Jongho; Lou, Jieqiong; Coelho, Simao; Lim, Yean Jin; Seidlitz, Silvia; Nicovich, Philip R.; Wunder, Christian; Johannes, Ludger; Gaus, Katharina

2017-04-01

Lattice light-sheet (LLS) microscopy provides ultrathin light sheets of a two-dimensional optical lattice that allows us imaging three-dimensional (3D) objects for hundreds of time points at sub-second intervals and at or below the diffraction limit. Galectin-3 (Gal3), a carbohydrate-binding protein, triggers glycosphingolipid (GSL)-dependent biogenesis of morphologically distinct endocytic vesicles that are cargo specific and clathrin independent. In this study, we apply LLS microscopy to study the dynamics of Gal3 dependent endocytosis in live T cells. This will allow us to observe Gal3-mediated endocytosis at high temporal and excellent 3D spatial resolution, which may shed light on our understanding of the mechanism and physiological function of Gal3-induced endocytosis.

Research on cutting path optimization of sheet metal parts based on ant colony algorithm

NASA Astrophysics Data System (ADS)

Wu, Z. Y.; Ling, H.; Li, L.; Wu, L. H.; Liu, N. B.

2017-09-01

In view of the disadvantages of the current cutting path optimization methods of sheet metal parts, a new method based on ant colony algorithm was proposed in this paper. The cutting path optimization problem of sheet metal parts was taken as the research object. The essence and optimization goal of the optimization problem were presented. The traditional serial cutting constraint rule was improved. The cutting constraint rule with cross cutting was proposed. The contour lines of parts were discretized and the mathematical model of cutting path optimization was established. Thus the problem was converted into the selection problem of contour lines of parts. Ant colony algorithm was used to solve the problem. The principle and steps of the algorithm were analyzed.

Assessment of present state-of-the-art sawing technology of large diameter ingots for solar sheet material

NASA Technical Reports Server (NTRS)

Yoo, H. I.

1977-01-01

The objective of this program is to assess the present state-of-the-art sawing technology of large diameter silicon ingots (3 inch and 4 inch diameter) for solar sheet materials. During this period, work has progressed in three areas: (1) slicing of the ingots with the multiblade slurry saw and the I.D. saw, (2) characterization of the sliced wafers, and (3) analysis of direct labor, expendable material costs, and wafer productivity.

My Favorite Assignment: From the ABC 2010 Annual Convention, Chicago, Illinois

ERIC Educational Resources Information Center

Whalen, D. Joel

2011-01-01

The seven Favorite Assignments featured in this article were originally presented at the 2010 ABC Annual Convention, Chicago, Illinois. The reader can consider a variety of learning objectives from team building to persuasion, application of electronic media to face-to-face communication, and much more. Some Favorite Assignments take a full…

Accounting for Protein Subcellular Localization: A Compartmental Map of the Rat Liver Proteome*

PubMed Central

Jadot, Michel; Boonen, Marielle; Thirion, Jaqueline; Wang, Nan; Xing, Jinchuan; Zhao, Caifeng; Tannous, Abla; Qian, Meiqian; Zheng, Haiyan; Everett, John K.; Moore, Dirk F.; Sleat, David E.; Lobel, Peter

2017-01-01

Accurate knowledge of the intracellular location of proteins is important for numerous areas of biomedical research including assessing fidelity of putative protein-protein interactions, modeling cellular processes at a system-wide level and investigating metabolic and disease pathways. Many proteins have not been localized, or have been incompletely localized, partly because most studies do not account for entire subcellular distribution. Thus, proteins are frequently assigned to one organelle whereas a significant fraction may reside elsewhere. As a step toward a comprehensive cellular map, we used subcellular fractionation with classic balance sheet analysis and isobaric labeling/quantitative mass spectrometry to assign locations to >6000 rat liver proteins. We provide quantitative data and error estimates describing the distribution of each protein among the eight major cellular compartments: nucleus, mitochondria, lysosomes, peroxisomes, endoplasmic reticulum, Golgi, plasma membrane and cytosol. Accounting for total intracellular distribution improves quality of organelle assignments and assigns proteins with multiple locations. Protein assignments and supporting data are available online through the Prolocate website (http://prolocate.cabm.rutgers.edu). As an example of the utility of this data set, we have used organelle assignments to help analyze whole exome sequencing data from an infant dying at 6 months of age from a suspected neurodegenerative lysosomal storage disorder of unknown etiology. Sequencing data was prioritized using lists of lysosomal proteins comprising well-established residents of this organelle as well as novel candidates identified in this study. The latter included copper transporter 1, encoded by SLC31A1, which we localized to both the plasma membrane and lysosome. The patient harbors two predicted loss of function mutations in SLC31A1, suggesting that this may represent a heretofore undescribed recessive lysosomal storage disease gene. PMID:27923875

Accounting for Protein Subcellular Localization: A Compartmental Map of the Rat Liver Proteome.

PubMed

Jadot, Michel; Boonen, Marielle; Thirion, Jaqueline; Wang, Nan; Xing, Jinchuan; Zhao, Caifeng; Tannous, Abla; Qian, Meiqian; Zheng, Haiyan; Everett, John K; Moore, Dirk F; Sleat, David E; Lobel, Peter

2017-02-01

Accurate knowledge of the intracellular location of proteins is important for numerous areas of biomedical research including assessing fidelity of putative protein-protein interactions, modeling cellular processes at a system-wide level and investigating metabolic and disease pathways. Many proteins have not been localized, or have been incompletely localized, partly because most studies do not account for entire subcellular distribution. Thus, proteins are frequently assigned to one organelle whereas a significant fraction may reside elsewhere. As a step toward a comprehensive cellular map, we used subcellular fractionation with classic balance sheet analysis and isobaric labeling/quantitative mass spectrometry to assign locations to >6000 rat liver proteins. We provide quantitative data and error estimates describing the distribution of each protein among the eight major cellular compartments: nucleus, mitochondria, lysosomes, peroxisomes, endoplasmic reticulum, Golgi, plasma membrane and cytosol. Accounting for total intracellular distribution improves quality of organelle assignments and assigns proteins with multiple locations. Protein assignments and supporting data are available online through the Prolocate website (http://prolocate.cabm.rutgers.edu). As an example of the utility of this data set, we have used organelle assignments to help analyze whole exome sequencing data from an infant dying at 6 months of age from a suspected neurodegenerative lysosomal storage disorder of unknown etiology. Sequencing data was prioritized using lists of lysosomal proteins comprising well-established residents of this organelle as well as novel candidates identified in this study. The latter included copper transporter 1, encoded by SLC31A1, which we localized to both the plasma membrane and lysosome. The patient harbors two predicted loss of function mutations in SLC31A1, suggesting that this may represent a heretofore undescribed recessive lysosomal storage disease gene. © 2017 by The American Society for Biochemistry and Molecular Biology, Inc.

Simulated and Real Sheet-of-Light 3D Object Scanning Using a-Si:H Thin Film PSD Arrays.

PubMed

Contreras, Javier; Tornero, Josep; Ferreira, Isabel; Martins, Rodrigo; Gomes, Luis; Fortunato, Elvira

2015-11-30

A MATLAB/SIMULINK software simulation model (structure and component blocks) has been constructed in order to view and analyze the potential of the PSD (Position Sensitive Detector) array concept technology before it is further expanded or developed. This simulation allows changing most of its parameters, such as the number of elements in the PSD array, the direction of vision, the viewing/scanning angle, the object rotation, translation, sample/scan/simulation time, etc. In addition, results show for the first time the possibility of scanning an object in 3D when using an a-Si:H thin film 128 PSD array sensor and hardware/software system. Moreover, this sensor technology is able to perform these scans and render 3D objects at high speeds and high resolutions when using a sheet-of-light laser within a triangulation platform. As shown by the simulation, a substantial enhancement in 3D object profile image quality and realism can be achieved by increasing the number of elements of the PSD array sensor as well as by achieving an optimal position response from the sensor since clearly the definition of the 3D object profile depends on the correct and accurate position response of each detector as well as on the size of the PSD array.

Spiral arms and massive star formation: Analysis of the CO face-on pictures of the galaxy

NASA Technical Reports Server (NTRS)

Clemens, D. P.; Sanders, D. B.; Scoville, N. Z.

1986-01-01

The face-on distribution of molecular gas in the first Galactic quadrant, derived from the Massachusetts-Stony Brook Galactic Plane CO Survey, was compared to the Galactic distribution of giant radio HII regions. The HII regions were found to preferentially select gas regions of higher than average density (more than twice the mean) and showed a strong correlation with the second power of the gas density. Systematic effects were tested with a Monte Carlo simulated HII region distribution and found to be negligible. The 135 HII regions were selected from the radio catalogs of Downes et at. (1980) and Wink et al. (1982). The HII regions were required to be within the CO survey 1 and b limits, within the solar circle, and not part of the 3 kpc expanding arm. The velocities of the HII regions were tabulated by the catalog authors and obvious associations with known objects and H2CO absorptions were used by them to assign distances. The distance assignments were here grouped into two categories; (1) those HII regions with definite distance assignments (85 objects); and (2) those HII regions with less secure distance assignments and those for which no near-far assignment was possible (50 objects).

Personal cooling apparatus and method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Siman-Tov, Moshe; Crabtree, Jerry Allen

2001-01-01

A portable lightweight cooling apparatus for cooling a human body is disclosed, having a channeled sheet which absorbs sweat and/or evaporative liquid, a layer of highly conductive fibers adjacent the channeled sheet; and, an air-moving device for moving air through the channeled sheet, wherein the layer of fibers redistributes heat uniformly across the object being cooled, while the air moving within the channeled sheet evaporates sweat and/or other evaporative liquid, absorbs evaporated moisture and the uniformly distributed heat generated by the human body, and discharges them into the environment. Also disclosed is a method for removing heat generated by themore » human body, comprising the steps of providing a garment to be placed in thermal communication with the body; placing a layer of highly conductive fibers within the garment adjacent the body for uniformly distributing the heat generated by the body; attaching an air-moving device in communication with the garment for forcing air into the garment; removably positioning an exchangeable heat sink in communication with the air-moving device for cooling the air prior to the air entering the garment; and, equipping the garment with a channeled sheet in communication with the air-moving device so that air can be directed into the channeled sheet and adjacent the layer of fibers to expell heat and moisture from the body by the air being directed out of the channeled sheet and into the environment. The cooling system may be configured to operate in both sealed and unsealed garments.« less

Personal cooling apparatus and method

DOE Office of Scientific and Technical Information (OSTI.GOV)

Siman-Tov, Moshe; Crabtree, Jerry Allen

A portable lightweight cooling apparatus for cooling a human body is disclosed, having a channeled sheet which absorbs sweat and/or evaporative liquid, a layer of highly conductive fibers adjacent the channeled sheet; and, an air-moving device for moving air through the channeled sheet, wherein the layer of fibers redistributes heat uniformly across the object being cooled, while the air moving within the channeled sheet evaporates sweat and/or other evaporative liquid, absorbs evaporated moisture and the uniformly distributed heat generated by the human body, and discharges them into the environment. Also disclosed is a method for removing heat generated by themore » human body, comprising the steps of providing a garment to be placed in thermal communication with the body; placing a layer of highly conductive fibers within the garment adjacent the body for uniformly distributing the heat generated by the body; attaching an air-moving device in communication with the garment for forcing air into the garment; removably positioning an exchangeable heat sink in communication with the air-moving device for cooling the air prior to the air entering the garment; and, equipping the garment with a channeled sheet in communication with the air-moving device so that air can be directed into the channeled sheet and adjacent the layer of fibers to expell heat and moisture from the body by the air being directed out of the channeled sheet and into the environment. The cooling system may be configured to operate in both sealed and unsealed garments.« less

Personal cooling apparatus and method

DOEpatents

Siman-Tov, Moshe; Crabtree, Jerry Allen

2001-01-01

A portable lightweight cooling apparatus for cooling a human body is disclosed, having a channeled sheet which absorbs sweat and/or evaporative liquid, a layer of highly conductive fibers adjacent the channeled sheet; and, an air-moving device for moving air through the channeled sheet, wherein the layer of fibers redistributes heat uniformly across the object being cooled, while the air moving within the channeled sheet evaporates sweat and/or other evaporative liquid, absorbs evaporated moisture and the uniformly distributed heat generated by the human body, and discharges them into the environment. Also disclosed is a method for removing heat generated by the human body, comprising the steps of providing a garment to be placed in thermal communication with the body; placing a layer of highly conductive fibers within the garment adjacent the body for uniformly distributing the heat generated by the body; attaching an air-moving device in communication with the garment for forcing air into the garment; removably positioning an exchangeable heat sink in communication with the air-moving device for cooling the air prior to the air entering the garment; and, equipping the garment with a channeled sheet in communication with the air-moving device so that air can be directed into the channeled sheet and adjacent the layer of fibers to expell heat and moisture from the body by the air being directed out of the channeled sheet and into the environment. The cooling system may be configured to operate in both sealed and unsealed garments.

Identification of Biomarkers for Footpad Dermatitis Development and Wound Healing

PubMed Central

Chen, Juxing; Tellez, Guillermo; Escobar, Jeffery

2016-01-01

Footpad dermatitis (FPD) is a type of skin inflammation that causes necrotic lesions on the plantar surface of the footpads in commercial poultry, with significant animal welfare, and economic implications. To identify biomarkers for FPD development and wound healing, a battery cage trial was conducted in which a paper sheet was put on the bottom of cages to hold feces to induce FPD of broilers. Day-of-hatch Ross 308 male broiler chicks were fed a corn–soybean meal diet and assigned to 3 treatments with 8 cages per treatment and 11 birds per cage. Cages without paper sheets were used as a negative control (NEG). Cages with paper sheets during the entire growth period (d 0–30) were used as a positive control (POS) to continually induce FPD. Cages with paper sheets during d 0–13 and without paper sheets during d 14–30 were used to examine the dynamic of FPD development and lesion wound healing (LWH). Footpad lesions were scored to grade (G) 1–5 with no lesion in G1 and most severe lesion in G5. Covering with paper sheets in POS and LWH induced 99% incidence of G3 footpads on d 13. Removing paper sheets from LWH healed footpad lesions by d 30. One representative bird, with lesions most close to pen average lesion score, was chosen to collect footpad skin samples for biomarker analysis. Total collagen protein and mRNA levels of tenascin X (TNX), type I α1 collagen (COL1A1), type III α1 collagen (COL3A1), tissue inhibitor of metalloproteinase 3 (TIMP3), and integrin α1 (ITGA1) mRNA levels were decreased (P < 0.05), while mRNA levels of tenascin C (TNC), tumor necrosis factor (TNF) α, Toll-like receptor (TLR) 4 and vascular endothelial growth factor (VEGF), IL-1β, and the ratio of MMP2 to all TIMP were increased (P < 0.03) in G3 footpads in POS and LWH compared to G1 footpads in NEG on d 14. These parameters continued to worsen with development of more severe lesions in POS. After paper sheets were removed (i.e., LWH), levels of these parameters gradually or rapidly returned to levels measured in NEG. Regression analysis indicated significant quadratic changes of these parameters to footpad lesion scores. In summary, these biomarkers were interrelated with dynamic changes of footpad lesion scores, suggesting they may be used as potential biomarkers for footpad lesion development and wound healing process. PMID:26973819

NMR resonance assignments of a hypoallergenic isoform of the major birch pollen allergen Bet v 1.

PubMed

Ahammer, Linda; Grutsch, Sarina; Wallner, Michael; Ferreira, Fatima; Tollinger, Martin

2017-10-01

In Northern America and Europe a great number of people are suffering from birch pollen allergy and pollen related food allergies. The trigger for these immunological reactions is the 17.5 kDa major birch pollen allergen Bet v 1, which belongs to the family of PR-10 (pathogenesis-related) proteins. In nature, Bet v 1 occurs as a mixture of various isoforms that possess different immunological properties despite their high sequence identities. Bet v 1.0102 (Bet v 1d), which is investigated here, is a hypoallergenic isoform of Bet v 1 and a potential candidate for allergen-specific immunotherapy. We assigned the backbone and side chain 1 H, 13 C and 15 N resonances of this protein and predicted its secondary structure. The NMR-chemical shift data indicate that Bet v 1.0102 is composed of three α-helices and a seven stranded β-sheet, in agreement with the known structure of the hyperallergenic isoform Bet v 1.0101 (Bet v 1a). Our resonance assignments create the foundation for detailed characterization of the dynamic properties of Bet v 1 isoforms by NMR relaxation measurements.

The Personal Computer in Mechanical Engineering Thermodynamics Courses.

ERIC Educational Resources Information Center

Romer, I. C., Jr.; Balmer, R. T.

1986-01-01

Describes experiences over several semesters with microcomputers in a mechanical engineering applied thermodynamics course. Includes course objectives, computer assignment structure, typical assignments, prewritten versus student-written software, and other topic areas. (JN)

The airport gate assignment problem: a survey.

PubMed

Bouras, Abdelghani; Ghaleb, Mageed A; Suryahatmaja, Umar S; Salem, Ahmed M

2014-01-01

The airport gate assignment problem (AGAP) is one of the most important problems operations managers face daily. Many researches have been done to solve this problem and tackle its complexity. The objective of the task is assigning each flight (aircraft) to an available gate while maximizing both conveniences to passengers and the operational efficiency of airport. This objective requires a solution that provides the ability to change and update the gate assignment data on a real time basis. In this paper, we survey the state of the art of these problems and the various methods to obtain the solution. Our survey covers both theoretical and real AGAP with the description of mathematical formulations and resolution methods such as exact algorithms, heuristic algorithms, and metaheuristic algorithms. We also provide a research trend that can inspire researchers about new problems in this area.

The Airport Gate Assignment Problem: A Survey

PubMed Central

Ghaleb, Mageed A.; Salem, Ahmed M.

2014-01-01

The airport gate assignment problem (AGAP) is one of the most important problems operations managers face daily. Many researches have been done to solve this problem and tackle its complexity. The objective of the task is assigning each flight (aircraft) to an available gate while maximizing both conveniences to passengers and the operational efficiency of airport. This objective requires a solution that provides the ability to change and update the gate assignment data on a real time basis. In this paper, we survey the state of the art of these problems and the various methods to obtain the solution. Our survey covers both theoretical and real AGAP with the description of mathematical formulations and resolution methods such as exact algorithms, heuristic algorithms, and metaheuristic algorithms. We also provide a research trend that can inspire researchers about new problems in this area. PMID:25506074

Curvature-induced stiffness and the spatial variation of wavelength in wrinkled sheets

PubMed Central

Hohlfeld, Evan; King, Hunter; Huang, Jiangshui; Qiu, Zhanlong; Russell, Thomas P.; Menon, Narayanan; Vella, Dominic; Davidovitch, Benny

2016-01-01

Wrinkle patterns in compressed thin sheets are ubiquitous in nature and technology, from the furrows on our foreheads to crinkly plant leaves, from ripples on plastic-wrapped objects to the protein film on milk. The current understanding of an elementary descriptor of wrinkles—their wavelength—is restricted to deformations that are parallel, spatially uniform, and nearly planar. However, most naturally occurring wrinkles do not satisfy these stipulations. Here we present a scheme that quantitatively explains the wrinkle wavelength beyond such idealized situations. We propose a local law that incorporates both mechanical and geometrical effects on the spatial variation of wrinkle wavelength. Our experiments on thin polymer films provide strong evidence for its validity. Understanding how wavelength depends on the properties of the sheet and the underlying liquid or elastic subphase is crucial for applications where wrinkles are used to sculpt surface topography, to measure properties of the sheet, or to infer forces applied to a film. PMID:26787902

Solution 1H NMR determination of secondary structure for the three-iron form of ferredoxin from the hyperthermophilic archaeon Pyrococcus furiosus.

PubMed

Teng, Q; Zhou, Z H; Smith, E T; Busse, S C; Howard, J B; Adams, M W; La Mar, G N

1994-05-24

Two-dimensional 1H NMR data have been used to make sequence-specific assignments and define the secondary structure of the three-iron form of the oxidized ferredoxin, Fd, from the hyperthermophilic archaeon Pyrococcus furiosus, Pf. Signals for at least some protons were located for 65 of the 66 amino acids in the sequence, in spite of the paramagnetic (S = 1/2) ground state, but not all could be assigned. Unassigned and missing signals could be qualitatively correlated with the expected proximity of the protons to the paramagnetic cluster. The secondary structure was deduced from qualitative analysis of the 2D nuclear Overhauser effect, which identified two antiparallel beta-sheets, one triple-stranded including Ala1-Ser5, Val39-Glu41, and Thr62-Ala66, and one double-stranded consisting of Glu26-Asn28 and Lys32-Glu34, as well as an alpha-helix involving Glu43-Glu54. Three tight type I turns are located at residues Asp7-Thr10, Pro22-Phe25, and Asp29-Gly31. Comparison with the crystal structure of Desulfovibrio gigas, Dg, Fd (Kissinger et al., 1991) reveals a very similar folding topology, although several secondary structural elements are extended in Pf relative to Dg Fd. Thus the beta-sheet involving the two termini is expanded to include the two terminal residues and incorporates a third strand from the internal loop that is lengthened by several insertions in Pf relative to Dg Fd. The double-stranded beta-sheet in the interior of Pf Fd is lengthened slightly due to a much tighter type I turn between the two strands. The helix near the C-terminus is three residues longer in Pf than in Dg Fd, as well as being shifted toward the N-terminus. The disulfide link between the two nonligating Cys residues (Cys21 and Cys48) is conserved in Pf Fd, but the link near the C-terminus is in the middle of the long alpha-helix in Pf Fd, instead of at the N-terminus of the helix as in Dg Fd. The extensions of the beta-sheets and alpha-helix increase the number of main-chain hydrogen bonds in Pf Fd by approximately 8 relative to those in Dg Fd and likely contribute to its remarkable thermostability (it is unaffected by anaerobic incubation at 95 degrees C for 24 h).(ABSTRACT TRUNCATED AT 400 WORDS)

Thin laser light sheet microscope for microbial oceanography

NASA Astrophysics Data System (ADS)

Fuchs, Eran; Jaffe, Jules S.; Long, Richard A.; Azam, Farooq

2002-01-01

Despite a growing need, oceanographers are limited by existing technological constrains and are unable to observe aquatic microbes in their natural setting. In order to provide a simple and easy to implement solution for such studies, a new Thin Light Sheet Microscope (TLSM) has been developed. The TLSM utilizes a well-defined sheet of laser light, which has a narrow (23 micron) axial dimension over a 1 mm x 1 mm field of view. This light sheet is positioned precisely within the depth of field of the microscope’s objective lens. The technique thus utilizes conventional microscope optics but replaces the illumination system. The advantages of the TLSM are two-fold: First, it concentrates light only where excitation is needed, thus maximizing the efficiency of the illumination source. Secondly, the TLSM maximizes image sharpness while at the same time minimizing the level of background noise. Particles that are not located within the objective's depth of field are not illuminated and therefore do not contribute to an out-of-focus image. Images from a prototype system that used SYBR Green I fluorescence stain in order to localize single bacteria are reported. The bacteria were in a relatively large and undisturbed volume of 4ml, which contained natural seawater. The TLSM can be used for fresh water studies of bacteria with no modification. The microscope permits the observation of interactions at the microscale and has potential to yield insights into how microbes structure pelagic ecosystems.

The Use of Homework Assignments in Physical Education among High School Students

ERIC Educational Resources Information Center

Pantanowitz, Michal; Lidor, Ronnie; Nemet, Dan; Eliakim, Alon

2011-01-01

Only a few studies have examined how students and their parents perceive the contribution of homework (HW) assignments given in physical education (PE) classes to the students' development. The main objective of our study was to explore the attitude and compliance towards HW assignments in PE among Israeli high school students and their parents.…

Parallel grid population

DOEpatents

Wald, Ingo; Ize, Santiago

2015-07-28

Parallel population of a grid with a plurality of objects using a plurality of processors. One example embodiment is a method for parallel population of a grid with a plurality of objects using a plurality of processors. The method includes a first act of dividing a grid into n distinct grid portions, where n is the number of processors available for populating the grid. The method also includes acts of dividing a plurality of objects into n distinct sets of objects, assigning a distinct set of objects to each processor such that each processor determines by which distinct grid portion(s) each object in its distinct set of objects is at least partially bounded, and assigning a distinct grid portion to each processor such that each processor populates its distinct grid portion with any objects that were previously determined to be at least partially bounded by its distinct grid portion.

Kelvin-Helmholtz instability of stratified jets.

NASA Astrophysics Data System (ADS)

Hanasz, M.; Sol, H.

1996-11-01

We investigate the Kelvin-Helmholtz instability of stratified jets. The internal component (core) is made of a relativistic gas moving with a relativistic bulk speed. The second component (sheath or envelope) flows between the core and external gas with a nonrelativistic speed. Such a two-component jet describes a variety of possible astrophysical jet configurations like e.g. (1) a relativistic electron-positron beam penetrating a classical electron-proton disc wind or (2) a beam-cocoon structure. We perform a linear stability analysis of such a configuration in the hydrodynamic, plane-parallel, vortex-sheet approximation. The obtained solutions of the dispersion relation show very apparent differences with respect to the single-jet solutions. Due to the reflection of sound waves at the boundary between sheet and external gas, the growth rate as a function of wavenumber presents a specific oscillation pattern. Overdense sheets can slow down the growth rate and contribute to stabilize the configuration. Moreover, we obtain the result that even for relatively small sheet widths the properties of sheet start to dominate the jet dynamics. Such effects could have important astrophysical implications, for instance on the origin of the dichotomy between radio-loud and radio-quiet objects.

Use of a gentamicin-impregnated collagen sheet (Collatamp(®)) in the management of major soft tissue complications in pediatric cochlear implants.

PubMed

Benito-González, Fernando; Benito, Jose; Sánchez, Luis Alberto Guardado; Estevez Alonso, Santiago; Muñoz Herrera, Angel; Batuecas-Caletrio, Angel

2014-09-01

The objective was to report the effectiveness of salvage treatment in soft tissue infection around cochlear implants with an absorbable gentamicin collagen sheet and a periosteum and skin rotation flaps. Three patients with cochlear implant and persistent surrounding soft tissue infection are included. All of them underwent antibiotic treatment prior to surgery without any response. In this study preoperative and postoperative audiograms were practiced. Surgical excision of infectious skin and a periosteum and skin rotation flaps were performed. The cochlear implant was refixed in the temporal bone and a gentamicin-impregnated collagen sheet was located covering the cochlear implant. headings In all patients with soft tissue infection around the cochlear implant, infection was completely resolved. It was not necessary to remove the device in any case. The use of an absorbable gentamicin-impregnated collagen sheet is not described for the management of soft tissue complications in pediatric cochlear implant patients. The local application of high concentrations of antibiotic administered by this sheet may be effective against resistant bacteria and, in conjunction with surgery, may resolve this type of complications.

Personalized disease-specific protein corona influences the therapeutic impact of graphene oxide.

PubMed

Hajipour, Mohammad Javad; Raheb, Jamshid; Akhavan, Omid; Arjmand, Sareh; Mashinchian, Omid; Rahman, Masoud; Abdolahad, Mohammad; Serpooshan, Vahid; Laurent, Sophie; Mahmoudi, Morteza

2015-05-21

The hard corona, the protein shell that is strongly attached to the surface of nano-objects in biological fluids, is recognized as the first layer that interacts with biological objects (e.g., cells and tissues). The decoration of the hard corona (i.e., the type, amount, and conformation of the attached proteins) can define the biological fate of the nanomaterial. Recent developments have revealed that corona decoration strongly depends on the type of disease in human patients from which the plasma is obtained as a protein source for corona formation (referred to as the 'personalized protein corona'). In this study, we demonstrate that graphene oxide (GO) sheets can trigger different biological responses in the presence of coronas obtained from various types of diseases. GO sheets were incubated with plasma from human subjects with different diseases/conditions, including hypofibrinogenemia, blood cancer, thalassemia major, thalassemia minor, rheumatism, fauvism, hypercholesterolemia, diabetes, and pregnancy. Identical sheets coated with varying protein corona decorations exhibited significantly different cellular toxicity, apoptosis, and uptake, reactive oxygen species production, lipid peroxidation and nitrogen oxide levels. The results of this report will help researchers design efficient and safe, patient-specific nano biomaterials in a disease type-specific manner for clinical and biological applications.

Assessment of the core learning objectives curriculum for the urology clerkship.

PubMed

Rapp, David E; Gong, Edward M; Reynolds, W Stuart; Lucioni, Alvaro; Zagaja, Gregory P

2007-11-01

The traditional approach to the surgical clerkship has limitations, including variability of clinical exposure. To optimize student education we developed and introduced the core learning objectives curriculum, which is designed to allow students freedom to direct their learning and focus on core concepts. We performed a prospective, randomized, controlled study to compare the efficacy of core learning objectives vs traditional curricula through objective and subjective measures. Medical students were randomly assigned to the core learning objectives or traditional curricula during the 2-week urology clerkship. Faculty was blinded to student assignment. Upon rotation completion all students were given a 20-question multiple choice examination covering basic urology concepts. In addition, students completed a questionnaire addressing subjective clerkship satisfaction, comprising 15 questions. Between June 2005 and January 2007, 10 core learning objectives students and 10 traditional students completed the urology clerkship. The average +/- SEM multiple choice examination score was 12.1 +/- 0.87 and 9.8 +/- 0.59 for students assigned to the core learning objectives and traditional curricula, respectively (p <0.05). Subjective scores were higher in the core learning objectives cohort, although this result did not attain statistical significance (124.9 +/- 3.72 vs 114.3 +/- 4.96, p = 0.1). Core learning objectives students reported higher satisfaction in all 15 assessed subjective end points. Our experience suggests that the core learning objectives model may be an effective educational tool to help students achieve a broad and directed exposure to the core urological concepts.

Sequential /sup 1/H NMR assignments and secondary structure of hen egg white lysozyme in solution

DOE Office of Scientific and Technical Information (OSTI.GOV)

Redfield, C.; Dobson, C.M.

Assignments of /sup 1/H NMR resonances of 121 of the 129 residues of hen egg white lysozyme have been obtained by sequence-specific methods. Spin systems were identified with phase-sensitive two-dimensional (2-D) correlated spectroscopy and single and double relayed coherence transfer spectroscopy. For key types of amino acid residues, particularly alanine, threonine, valine, and glycine, complete spin systems were identified. For other residues a less complete definition of the spin system was found to be adequate for the purpose of sequential assignment. Sequence-specific assignments were achieved by phase-sensitive 2-D nuclear Overhauser enhancement spectroscopy (NOESY). Exploitation of the wide range of hydrogenmore » exchange rates found in lysozyme was a useful approach to overcoming the problem of spectral overlap. The sequential assignment was built up from 21 peptide segments ranging in length from 2 to 13 residues. The NOESY spectra were also used to provide information about the secondary structure of the protein in solution. Three helical regions and two regions of ..beta..-sheet were identified from the NOESY data; these regions are identical with those found in the X-ray structure of hen lysozyme. Slowly exchanging amides are generally correlated with hydrogen bonding identified in the X-ray structure; a number of exceptions to this general trend were, however, found. The results presented in this paper indicate that highly detailed information can be obtained from 2-D NMR spectra of a protein that is significantly larger than those studies previously.« less

Effect of CFRP Schemes on the Flexural Behavior of RC Beams Modeled by Using a Nonlinear Finite-element Analysis

NASA Astrophysics Data System (ADS)

Al-Rousan, R. Z.

2015-09-01

The main objective of this study was to assess the effect of the number and schemes of carbon-fiber-reinforced polymer (CFRP) sheets on the capacity of bending moment, the ultimate displacement, the ultimate tensile strain of CFRP, the yielding moment, concrete compression strain, and the energy absorption of RC beams and to provide useful relationships that can be effectively utilized to determine the required number of CFRP sheets for a necessary increase in the flexural strength of the beams without a major loss in their ductility. To accomplish this, various RC beams, identical in their geometric and reinforcement details and having different number and configurations of CFRP sheets, are modeled and analyzed using the ANSYS software and a nonlinear finite-element analysis.

Formation of Sprays From Conical Liquid Sheets

NASA Technical Reports Server (NTRS)

Peck, Bill; Mansour, N. N.; Koga, Dennis (Technical Monitor)

1999-01-01

Our objective is to predict droplet size distributions created by fuel injector nozzles in Jet turbines. These results will be used to determine the initial conditions for numerical simulations of the combustion process in gas turbine combustors. To predict the droplet size distribution, we are currently constructing a numerical model to understand the instability and breakup of thin conical liquid sheets. This geometry serves as a simplified model of the liquid jet emerging from a real nozzle. The physics of this process is difficult to study experimentally as the time and length scales are very short. From existing photographic data, it does seem clear that three-dimensional effects such as the formation of streamwise ligaments and the pulling back of the sheet at its edges under the action of surface tension are important.

Space Object Query Tool

NASA Technical Reports Server (NTRS)

Phillips, Veronica J.

2017-01-01

STI is for a fact sheet on the Space Object Query Tool being created by the MDC. When planning launches, NASA must first factor in the tens of thousands of objects already in orbit around the Earth. The number of human-made objects, including nonfunctional spacecraft, abandoned launch vehicle stages, mission-related debris and fragmentation debris orbiting Earth has grown steadily since Sputnik 1 was launched in 1957. Currently, the U.S. Department of Defenses Joint Space Operations Center, or JSpOC, tracks over 15,000 distinct objects and provides data for more than 40,000 objects via its Space-Track program, found at space-track.org.

The GLAS Standard Data Products Specification-Level 1, Version 9

NASA Technical Reports Server (NTRS)

Lee, Jeffrey E.

2013-01-01

The Geoscience Laser Altimeter System (GLAS) is the primary instrument for the ICESat (Ice, Cloud and Land Elevation Satellite) laser altimetry mission. ICESat was the benchmark Earth Observing System (EOS) mission for measuring ice sheet mass balance, cloud and aerosol heights, as well as land topography and vegetation characteristics. From 2003 to 2009, the ICESat mission provided multi-year elevation data needed to determine ice sheet mass balance as well as cloud property information, especially for stratospheric clouds common over polar areas. It also provided topography and vegetation data around the globe, in addition to the polar-specific coverage over the Greenland and Antarctic ice sheets.This document defines the Level-1 GLAS standard data products. This document addresses the data flow, interfaces, record and data formats associated with the GLAS Level 1 standard data products. GLAS Level 1 standard data products are composed of Level 1A and Level 1B data products. The term standard data products refers to those EOS instrument data that are routinely generated for public distribution. The National Snow and Ice Data Center (NSDIC) distribute these products. Each data product has a unique Product Identification code assigned by the Senior Project Scientist. GLAS Level 1A and Level 1B Data Products are composed from those Level 0 data that have been reformatted or transformed to corrected and calibrated data in physical units at the full instrument rate and resolution.

Protein structure and the sequential structure of mRNA: alpha-helix and beta-sheet signals at the nucleotide level.

PubMed

Brunak, S; Engelbrecht, J

1996-06-01

A direct comparison of experimentally determined protein structures and their corresponding protein coding mRNA sequences has been performed. We examine whether real world data support the hypothesis that clusters of rare codons correlate with the location of structural units in the resulting protein. The degeneracy of the genetic code allows for a biased selection of codons which may control the translational rate of the ribosome, and may thus in vivo have a catalyzing effect on the folding of the polypeptide chain. A complete search for GenBank nucleotide sequences coding for structural entries in the Brookhaven Protein Data Bank produced 719 protein chains with matching mRNA sequence, amino acid sequence, and secondary structure assignment. By neural network analysis, we found strong signals in mRNA sequence regions surrounding helices and sheets. These signals do not originate from the clustering of rare codons, but from the similarity of codons coding for very abundant amino acid residues at the N- and C-termini of helices and sheets. No correlation between the positioning of rare codons and the location of structural units was found. The mRNA signals were also compared with conserved nucleotide features of 16S-like ribosomal RNA sequences and related to mechanisms for maintaining the correct reading frame by the ribosome.

Space Station needs, attributes and architectural options. Volume 2, book 1, part 4: Payload element mission data sheets

NASA Technical Reports Server (NTRS)

1984-01-01

Data sheets are presented for 11 internal payloads, 30 externally mounted payloads, and 46 free flyers. The importance of the space station to each payload element is rated on a scale of 1 to 10. The type of experiment noncommercial science and applications, commercial, technological, and operational is indicated and the payload and its objectives are described. Space is provided for noting requirements for power; data/communication; thermal environment; equipment physical characteristics; crew size; and service and maintenance.

High-fidelity large area nano-patterning of silicon with femtosecond light sheet

NASA Astrophysics Data System (ADS)

Sidhu, Mehra S.; Munjal, Pooja; Singh, Kamal P.

2018-01-01

We employ a femtosecond light sheet generated by a cylindrical lens to rapidly produce high-fidelity nano-structures over large area on silicon surface. The Fourier analysis of electron microscopy images of the laser-induced surface structures reveals sharp peaks indicating good homogeneity. We observed an emergence of second-order spatial periodicity on increasing the scan speed. Our reliable approach may rapidly nano-pattern curved solid surfaces and tiny objects for diverse potential applications in optical devices, structural coloring, plasmonic substrates and in high-harmonic generation.

Characterizing the Secondary Protein Structure of Black Widow Dragline Silk Using Solid-State NMR & X-ray Diffraction

PubMed Central

Jenkins, Janelle E.; Sampath, Sujatha; Butler, Emily; Kim, Jihyun; Henning, Robert W.; Holland, Gregory P.; Yarger, Jeffery L.

2013-01-01

This study provides a detailed secondary structural characterization of major ampullate dragline silk from Latrodectus hesperus (black widow) spiders. X-ray diffraction results show that the structure of black widow major ampullate silk fibers is comprised of stacked β-sheet nanocrystallites oriented parallel to the fiber axis and an amorphous region with oriented (anisotropic) and isotropic components. The combination of two-dimensional (2D) 13C-13C through-space and through-bond solid-state NMR experiments provide chemical shifts that are used to determine detailed information about amino acid motif secondary structure in black widow spider dragline silk. Individual amino acids are incorporated into different repetitive motifs that make up the majority of this protein-based biopolymer. From the solid-state NMR measurements, we assign distinct secondary conformations to each repetitive amino acid motif and hence to the amino acids that make up the motifs. Specifically, alanine is incorporated in β-sheet (poly(Alan) and poly(Gly-Ala)), 31-helix (poly(Gly-Gly-Xaa), and α-helix (poly(Gln-Gln-Ala-Tyr)) components. Glycine is determined to be in β-sheet (poly(Gly-Ala)) and 31-helical (poly(Gly-Gly-Xaa)) regions, while serine is present in β-sheet (poly(Gly-Ala-Ser)), 31-helix (poly(Gly-Gly-Ser)), and β-turn (poly(Gly-Pro-Ser)) structures. These various motif-specific secondary structural elements are quantitatively correlated to the primary amino acid sequence of major ampullate spidroin 1 and 2 (MaSp1 and MaSp2) and are shown to form a self-consistent model for black widow dragline silk. PMID:24024617

Three-dimensional fluorescent microscopy via simultaneous illumination and detection at multiple planes.

PubMed

Ma, Qian; Khademhosseinieh, Bahar; Huang, Eric; Qian, Haoliang; Bakowski, Malina A; Troemel, Emily R; Liu, Zhaowei

2016-08-16

The conventional optical microscope is an inherently two-dimensional (2D) imaging tool. The objective lens, eyepiece and image sensor are all designed to capture light emitted from a 2D 'object plane'. Existing technologies, such as confocal or light sheet fluorescence microscopy have to utilize mechanical scanning, a time-multiplexing process, to capture a 3D image. In this paper, we present a 3D optical microscopy method based upon simultaneously illuminating and detecting multiple focal planes. This is implemented by adding two diffractive optical elements to modify the illumination and detection optics. We demonstrate that the image quality of this technique is comparable to conventional light sheet fluorescent microscopy with the advantage of the simultaneous imaging of multiple axial planes and reduced number of scans required to image the whole sample volume.

Metallurgical characterization of brass objects from the Akko 1 shipwreck, Israel

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ashkenazi, D., E-mail: dana@eng.tau.ac.il; Cvikel, D.; Stern, A.

2014-06-01

The Akko 1 shipwreck was a small Egyptian armed vessel or auxiliary naval brig built in the eastern Mediterranean at the beginning of the 19th century. During the underwater excavations, about 230 brass hook-and-eye closures were found, mainly in the bow area. In addition, 158 brass cases were found, mainly between midships and the aft extremity of the shipwreck. Metallurgical non-destructive and destructive characterizations of selected items were performed, including radiographic testing, XRF, lead isotope analysis, optical microscopy, SEM–EDS and microhardness tests. The hook-and-eye closures and the cases were both found to be made of binary copper–zinc alloy (about 30more » wt.% zinc). While the brass cases were made from rolled sheets, hand-made using simple tools, and joined by tin–lead soldering material, the brass hook-and-eye closures were hand-made from drawn brass wire, and manufactured from commercial drawn brass bars by a cold-working process. The lead isotope analyses suggest different provenances of the raw materials used for making the brass objects, thus the different origins of the ores may hint that the brass wire and sheet were imported to the workshops in which the objects were manufactured. - Highlights: • Brass cases and hook-and-eye closures were retrieved from the Akko 1 shipwreck. • Both types of objects were made of binary copper–zinc alloy (about 30 wt.% zinc). • The cases were hand-made from rolled sheets and joined by tin–lead soldering. • Hook-and-eye closures were made from drawn brass wire manufactured by cold-working. • Lead isotope analyses suggest that the origins of the raw material were diverse.« less

Nature of science in instruction materials of science through the model of educational reconstruction

NASA Astrophysics Data System (ADS)

Azizah, Nur; Mudzakir, Ahmad

2016-02-01

The study was carried out to reconstruct the science teaching materials charged view of the nature of science (VNOS). This reconstruction process using the Model of Educational Reconstruction (MER), which is the framework for research and development of science education as well as a guide for planning the teaching of science in the schools is limited in two stages, namely: content structure analysis, and empirical studies of learners. The purpose of this study is to obtain a pre-conception of learners and prospective scientists to the topic of the nature of the material and utilization. The method used to descriptive with the instruments is guidelines for interviews for 15 students of class VIII, text analysis sheet, sheet analysis of the concept, and the validation sheet indicators and learning objectives NOS charged on cognitive and affective aspects. The results obtained in the form of pre-conceptions of learners who demonstrate almost 100% of students know the types of materials and some of its nature, the results of the scientist's perspective on the topic of the nature of the material and its use, as well as the results of the validation indicators and learning objectives charged NOS and competencies PISA 2015 cognitive and affective aspects with CVI value of 0.99 and 1.0 after being validated by five experts. This suggests that the indicators and the resulting learning objectives feasible and can proceed to the reconstruction of teaching materials on the topic of material properties and utilization.

NEPA assignment training PowerPoints and quizzes.

DOT National Transportation Integrated Search

2016-10-01

The objective of these training materials is to provide National Environmental : Policy Act (NEPA) Assignment information to all professionals involved in the NEPA : process. This training is not intended to be a replication of existing NEPA training...

Awareness-based game-theoretic space resource management

NASA Astrophysics Data System (ADS)

Chen, Genshe; Chen, Huimin; Pham, Khanh; Blasch, Erik; Cruz, Jose B., Jr.

2009-05-01

Over recent decades, the space environment becomes more complex with a significant increase in space debris and a greater density of spacecraft, which poses great difficulties to efficient and reliable space operations. In this paper we present a Hierarchical Sensor Management (HSM) method to space operations by (a) accommodating awareness modeling and updating and (b) collaborative search and tracking space objects. The basic approach is described as follows. Firstly, partition the relevant region of interest into district cells. Second, initialize and model the dynamics of each cell with awareness and object covariance according to prior information. Secondly, explicitly assign sensing resources to objects with user specified requirements. Note that when an object has intelligent response to the sensing event, the sensor assigned to observe an intelligent object may switch from time-to-time between a strong, active signal mode and a passive mode to maximize the total amount of information to be obtained over a multi-step time horizon and avoid risks. Thirdly, if all explicitly specified requirements are satisfied and there are still more sensing resources available, we assign the additional sensing resources to objects without explicitly specified requirements via an information based approach. Finally, sensor scheduling is applied to each sensor-object or sensor-cell pair according to the object type. We demonstrate our method with realistic space resources management scenario using NASA's General Mission Analysis Tool (GMAT) for space object search and track with multiple space borne observers.

[Development, implementation, and analysis of a "collaborative decision-making for reasonable care" document in pediatric palliative care].

PubMed

Paoletti, M; Litnhouvongs, M-N; Tandonnet, J

2015-05-01

In France, a legal framework and guidelines state that decisions to limit treatments (DLT) require a collaborative decision meeting and a transcription of decisions in the patient's file. The do-not-attempt-resuscitation order involves the same decision-making process for children in palliative care. To fulfill the law's requirements and encourage communication within the teams, the Resource Team in Pediatric Palliative Care in Aquitaine created a document shared by all children's hospital units, tracing the decision-making process. This study analyzed the decision-making process, quality of information transmission, and most particularly the relevance of this new "collaborative decision-making for reasonable care" card. Retrospective study evaluating the implementation of a traceable document relating the DLT process. All the data sheets collected between January and December 2013 were analyzed. A total of 58 data sheets were completed between January and December 2013. We chose to collect the most relevant data to evaluate the relevance of the items to be completed and the transmission of the document, to draw up the patients' profile, and the contents of discussions with families. Of the 58 children for whom DLT was discussed, 41 data sheets were drawn up in the pediatric intensive care unit, seven in the oncology and hematology unit, five in the neonatology unit, four in the neurology unit, and one in the pneumology unit. For 30 children, one sheet was created, for 11 children, two sheets and for two children, three sheets were filled out. Thirty-nine decisions were made for withholding lifesaving treatment, 11 withdrawing treatment, and for five children, no limitation was set. Nine children survived after DLT. Of the 58 data sheets, only 31 discussions with families were related to the content of the data sheet. Of the 14 children transferred out of the unit with a completed data sheet, it was transmitted to the new unit for 11 children (79%). The number of data sheets collected in 1 year shows the value of this document. The participation of several pediatric specialities' referents in its creation, then its progressive presentation in the children's hospital units, were essential steps in introducing and establishing its use. Items describing the situation, management proposals, and adaptation of the children's supportive care were completed in the majority of cases. They correspond to a clinical description, the object of the discussion, and the daily caregiver's practices, respectively. On the other hand, discussions with families were related to the card's contents in only 53% of the cases. This can be explained by the time required to complete the DLT process. It is difficult for referring doctors to systematically, faithfully, and objectively transcribe discussions with parents. Although this process has been used for a long time in intensive care units, this document made possible an indispensable formalisation in the decision-making process. In other pediatric specialities, the sheet allowed introducing the palliative approach and was a starter and a tool for reflection on the do-not-attempt-resuscitation order, thus suggesting the need for anticipation in these situations. With the implementation of this new document, the DLT, data transmission, and continuity of care conditions were improved in the children's hospital units. Sharing this sheet with all professionals in charge of these children would support homogeneity and quality of management and care for children and their parents. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

Porcine wound healing in full-thickness skin defects using Integra™ with and without fibrin glue with keratinocytes

PubMed Central

Melendez, Mark M; Martinez, Rodrigo R; Dagum, Alexander B; McClain, Steve A; Simon, Marcia; Sobanko, Joseph; Zimmerman, Thomas; Wetterau, Meredith; Muller, Douglas; Xu, Xiaoti; Singer, Adam J; Arora, Balvantray

2008-01-01

BACKGROUND: An artificial dermal matrix such as Integra (Integra Life Sciences Corporation, USA) provides a wound bed template for vascular and fibrocyte ingrowth as well as collagen remodelling. Dermal repair leads to epidermal and basement membrane regeneration. Burn wounds in particular have been shown to benefit from Integra by enhanced wound healing. OBJECTIVE: To evaluate the effect of fibrin glue to modify the integration of Integra in large excised cutaneous wounds. It was hypothesized that applying fibrin glue on a wound bed would reduce the time needed for matrix vascularization and incorporation of Integra and take of the cultured keratinocytes. METHODS: Four separate full-thickness wounds were created on the dorsum of two swine. Wound beds were randomly assigned to either application of fibrin glue or no application of fibrin glue before application of Integra. Full-thickness biopsies were performed at days 7, 14, 21, 29 and 35. On day 21, keratinocytes were applied either as sheets or aerosolized fibrin glue suspension. RESULTS: Histological analysis revealed a wave of inflammatory cells and early granulation tissue ingrowth into the Integra from the fascia below on day 7. Only this initial phase was augmented by application of fibrin glue to the wound bed. By day 14, most and by day 21, all of the Integra thickness was incorporated. Accelerated dermal repair proceeded from the base with new collagen deposition in Integra spaces. There was no evidence of keratinocyte engraftment, although re-epithelialization occurred at wound edges extending onto the incorporated Integra. CONCLUSIONS: It appears there is an acceleration of early phase (day 7 to day 21) dermal incorporation with fibrin glue application to the wound bed, perhaps secondary to increased cellular migration. Day 21 appears to be too early to apply cultured keratinocytes either as sheets or aerosolized suspension. PMID:19721792

Climate Proxies: An Inquiry-Based Approach to Discovering Climate Change on Antarctica

NASA Astrophysics Data System (ADS)

Wishart, D. N.

2016-12-01

An attractive way to advance climate literacy in higher education is to emphasize its relevance while teaching climate change across the curriculum to science majors and non-science majors. An inquiry-based pedagogical approach was used to engage five groups of students on a "Polar Discovery Project" aimed at interpreting the paleoclimate history of ice cores from Antarctica. Learning objectives and student learning outcomes were clearly defined. Students were assigned several exercises ranging from examination of Antarctic topography to the application of physical and chemical measurements as proxies for climate change. Required materials included base and topographic maps of Antarctica; graph sheets for construction of topographic cross-sectional profiles from profile lines of the Western Antarctica Ice Sheet (WAIS) Divide and East Antarctica; high-resolution photographs of Antarctic ice cores; stratigraphic columns of ice cores; borehole and glaciochemical data (i.e. anions, actions, δ18O, δD etc.); and isotope data on greenhouse gases (CH4, O2, N2) extracted from gas bubbles in ice cores. The methodology was to engage students in (2) construction of topographic profiles; (2) suggest directions for ice flow based on simple physics; (3) formulate decisions on suitable locations for drilling ice cores; (4) visual ice stratigraphy including ice layer counting; (5) observation of any insoluble particles (i.e. meteoritic and volcanic material); (6) analysis of borehole temperature profiles; and (7) the interpretation of several datasets to derive a paleoclimate history of these areas of the continent. The overall goal of the project was to improve the students analytical and quantitative skills; their ability to evaluate relationships between physical and chemical properties in ice cores, and to advance the understanding the impending consequences of climate change while engaging science, technology, engineering and mathematics (STEM). Student learning outcomes were assessed at the completion of the `Polar Discovery Project' for their curiosity, analytical strength, creativity, group collaboration, problem-solving, innovation, and interest in level climate change and the implications of the its effects on polar regions.

Hazard Analysis for Pneumatic Flipper Suitport/Z-1 Manned Evaluation, Chamber B, Building 32. Revision: Basic

NASA Technical Reports Server (NTRS)

2012-01-01

One of the characteristics of an effective safety program is the recognition and control of hazards before mishaps or failures occur. Conducting potentially hazardous tests necessitates a thorough hazard analysis in order to protect our personnel from injury and our equipment from damage. The purpose of this hazard analysis is to define and address the potential hazards and controls associated with the Z1 Suit Port Test in Chamber B located in building 32, and to provide the applicable team of personnel with the documented results. It is imperative that each member of the team be familiar with the hazards and controls associated with his/her particular tasks, assignments, and activities while interfacing with facility test systems, equipment, and hardware. The goal of this hazard analysis is to identify all hazards that have the potential to harm personnel and/or damage facility equipment, flight hardware, property, or harm the environment. This analysis may also assess the significance and risk, when applicable, of lost test objectives when substantial monetary value is involved. The hazards, causes, controls, verifications, and risk assessment codes have been documented on the hazard analysis work sheets in appendix A of this document. The preparation and development of this report is in accordance with JPR 1700.1, JSC Safety and Health Handbook.

Synthesis, crystal structure, and vibrational spectroscopic and UV-visible studies of Cs{sub 2}MnP{sub 2}O{sub 7}

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kaoua, Saida; Krimi, Saida; Pechev, Stanislav

2013-02-15

A new member of the A{sub 2}MP{sub 2}O{sub 7} diphosphate family, Cs{sub 2}MnP{sub 2}O{sub 7}, has been synthesized and structurally characterized. The crystal structure was determined by single crystal X-Ray diffraction. Cs{sub 2}MnP{sub 2}O{sub 7} crystallizes in the orthorhombic system, space group Pnma ( Music-Sharp-Sign 62), with the unit cell parameters a=16.3398(3), b=5.3872(1), c=9.8872(2) A, Z=4 and V=870.33(3) A{sup 3}. The structure parameters were refined to a final R{sub 1}/wR{sub 2}=0.0194/0.0441 for 1650 observed reflections. The 2D framework of Cs{sub 2}MnP{sub 2}O{sub 7} structure consists of P{sub 2}O{sub 7} and MnO{sub 5} units. The corner-shared MnO{sub 5} and P{sub 2}O{submore » 7} units are alternately arranged along the b axis to form [(MnO)P{sub 2}O{sub 7}]{sub {infinity}} chains. These chains are interconnected by an oxygen atom to form sheets parallel to the (b, c) plane. The cesium atoms are located between the sheets in 9- and 10-fold coordinated sites. The infrared and Raman vibrational spectra have been investigated. A factor group analysis leads to the determination of internal modes of (P{sub 2}O{sub 7}) groups. UV-visible spectrum consists of weak bands, between 340 and 700 nm, assigned to the forbidden d-d transitions of Mn{sup 2+} ion, and of a strong band around 250 nm, attributed to the O--Mn charge transfer. - Graphical abstract: Structure of Cs{sub 2}MnP{sub 2}O{sub 7}: The 2D structure of Cs{sub 2}MnP{sub 2}O{sub 7} is built from P{sub 2}O{sub 7} diphosphate groups and MnO{sub 5} square pyramids which share corners and form [(MnO)P{sub 2}O{sub 7}]{sub {infinity}} chains along b axis. These chains are interconnected by an oxygen atom to form wavy (MnP{sub 2}O{sub 7}){sup 2-} sheets parallel to the (b, c) plane. The cesium ions are located between these sheets in the inter-layers space, in zigzag positions. Highlights: Black-Right-Pointing-Pointer A new diphosphate, Cs{sub 2}MnP{sub 2}O{sub 7}, has been synthesized and structurally characterized. Black-Right-Pointing-Pointer The structure consists of a 2D framework built up from (MnP{sub 2}O{sub 7}) sheets. Black-Right-Pointing-Pointer The sheets consist of [(MnO)P{sub 2}O{sub 7}]{sub {infinity}} chains formed by P{sub 2}O{sub 7} units and MnO{sub 5} square pyramids. Black-Right-Pointing-Pointer A factor group analysis leads to the determination of internal modes of (P{sub 2}O{sub 7}) groups. Black-Right-Pointing-Pointer UV-visible spectrum consists bands assigned to d-d transitions of Mn{sup 2+} ion and to O--Mn CT.« less

Error Checking and Graphical Representation of Multiple–Complete–Digest (MCD) Restriction-Fragment Maps

PubMed Central

Thayer, Edward C.; Olson, Maynard V.; Karp, Richard M.

1999-01-01

Genetic and physical maps display the relative positions of objects or markers occurring within a target DNA molecule. In constructing maps, the primary objective is to determine the ordering of these objects. A further objective is to assign a coordinate to each object, indicating its distance from a reference end of the target molecule. This paper describes a computational method and a body of software for assigning coordinates to map objects, given a solution or partial solution to the ordering problem. We describe our method in the context of multiple–complete–digest (MCD) mapping, but it should be applicable to a variety of other mapping problems. Because of errors in the data or insufficient clone coverage to uniquely identify the true ordering of the map objects, a partial ordering is typically the best one can hope for. Once a partial ordering has been established, one often seeks to overlay a metric along the map to assess the distances between the map objects. This problem often proves intractable because of data errors such as erroneous local length measurements (e.g., large clone lengths on low-resolution physical maps). We present a solution to the coordinate assignment problem for MCD restriction-fragment mapping, in which a coordinated set of single-enzyme restriction maps are simultaneously constructed. We show that the coordinate assignment problem can be expressed as the solution of a system of linear constraints. If the linear system is free of inconsistencies, it can be solved using the standard Bellman–Ford algorithm. In the more typical case where the system is inconsistent, our program perturbs it to find a new consistent system of linear constraints, close to those of the given inconsistent system, using a modified Bellman–Ford algorithm. Examples are provided of simple map inconsistencies and the methods by which our program detects candidate data errors and directs the user to potential suspect regions of the map. PMID:9927487

Fluctuations in Conjunction Miss Distance Projections as Time Approaches Time of Closest Approach

NASA Technical Reports Server (NTRS)

Christian, John A., III

2005-01-01

A responsibility of the Trajectory Operations Officer is to ensure that the International Space Station (ISS) avoids colliding with debris. United States Space Command (USSPACECOM) tracks and catalogs a portion of the debris in Earth orbit, but only objects with a perigee less than 600 km and a radar cross section (RCS) greater than 10 cm-objects that, in fact, represent only a small fraction of the objects in Earth orbit. To accommodate for this, the ISS uses shielding to protect against collisions with smaller objects. This study provides a better understanding of how quickly, and to what degree, USSPACECOM projections tend to converge to the final, true miss distance. The information included is formulated to better predict the behavior of miss distance data during real-time operations. It was determined that the driving components, in order of impact on miss distance fluctuations, are energy dissipation rate (EDR), RCS, and inclination. Data used in this analysis, calculations made, and conclusions drawn are stored in Microsoft Excel log sheets. A separate log sheet, created for each conjunction, contains information such as predicted miss distances, apogee and perigee of debris orbit, EDR, RCS, inclination, tracks and observations, statistical data, and other evaluation/orbital parameters.

Applications of Future NASA Decadal Missions for Observing Earth's Land and Water Processes

NASA Technical Reports Server (NTRS)

Luvall, Jeffrey C.; Hook, Simon; Brown, Molly E.; Tzortziou, Maria A.; Carroll, Mark; Escobar, Vanessa M.; Omar, Ali

2013-01-01

Misson Objective: To collect altimetry data of the Earth's surface optimized to measure ice sheet elevation change and sea ice thickness, while also generating an estimate of global vegetation biomass.

Computer-Aided Engineering Of Cabling

NASA Technical Reports Server (NTRS)

Billitti, Joseph W.

1989-01-01

Program generates data sheets, drawings, and other information on electrical connections. DFACS program, centered around single data base, has built-in menus providing easy input of, and access to, data for all personnel involved in system, subsystem, and cabling. Enables parallel design of circuit-data sheets and drawings of harnesses. Also recombines raw information to generate automatically various project documents and drawings, including index of circuit-data sheets, list of electrical-interface circuits, lists of assemblies and equipment, cabling trees, and drawings of cabling electrical interfaces and harnesses. Purpose of program to provide engineering community with centralized data base for putting in, and gaining access to, functional definition of system as specified in terms of details of pin connections of end circuits of subsystems and instruments and data on harnessing. Primary objective to provide instantaneous single point of interchange of information, thus avoiding

Design, assembly, and metrology of an oil-immersion microscope objective with long working distance

NASA Astrophysics Data System (ADS)

Peng, Wei-Jei; Lin, Wen-Lung; Kuo, Hui-Jean; Ho, Cheng-Fang; Hsu, Wei-Yao

2016-10-01

The design, tolerance sensitivity reduction, assembly, and optical bench test for an oil-immersion microscope objective with long working distance employed in a lattice light-sheet microscope is presented in this paper. In this application, the orthogonal excitation and detection objectives are dipped in an oil medium. The excitation objective focuses the incident laser beam to generate fluorescence on specimen for collecting by detection objective. The excitation objective is custom-designed to meet the requirement specification such as oil-immersion, the long working distance, and numerical aperture (NA) of 0.5, etc. To produce an acceptable point spread function (PSF) for effective excitation, the performance of the objective needs to be close to diffraction limit. Because the tolerance of the modulation transfer function (MTF) is more and more sensitive at higher spatial frequency, it is extremely critical to keep the performance after manufacture. Consequently, an insensitive optical design is very important for relaxing tolerance. We compare the design with and without tolerance sensitivity reduction, and the as-built MTF shows the result. Furthermore, the method for sensitivity reduction is presented. The opto-mechanical design and assembly method are also discussed. Eventually, the objective with five spherical lenses was fabricated. In optical bench test, the depth of the oil is sensitive to MTF, and it leads to the complicated adjustment. For solving this issue, we made an index-matching lens to replace oil for measurement easily. Finally, the measured MTF of the excitation objective can accomplish the requirement specification and successfully employed in a lattice light-sheet microscope.

Developing learning community model with soft skill integration for the building engineering apprenticeship programme in vocational high school

NASA Astrophysics Data System (ADS)

Sutrisno, Dardiri, Ahmad; Sugandi, R. Machmud

2017-09-01

This study aimed to address the procedure, effectiveness, and problems in the implementation of learning model for Building Engineering Apprenticeship Training Programme. This study was carried out through survey method and experiment. The data were collected using questionnaire, test, and assessment sheet. The collected data were examined through description, t-test, and covariance analysis. The results of the study showed that (1) the model's procedure covered preparation course, readiness assessment, assignment distribution, handing over students to apprenticeship instructors, task completion, assisting, field assessment, report writing, and follow-up examination, (2) the Learning Community model could significantly improve students' active learning, but not improve students' hard skills and soft skills, and (3) the problems emerging in the implementation of the model were (1) students' difficulties in finding apprenticeship places and qualified instructors, and asking for relevant tasks, (2) teachers' difficulties in determining relevant tasks and monitoring students, and (3) apprenticeship instructors' difficulties in assigning, monitoring, and assessing students.

Sheetmetal. Performance Objectives. Basic Course.

ERIC Educational Resources Information Center

Murwin, Roland

Several intermediate performance objectives and corresponding criterion measures are listed for each of six terminal objectives for a basic high school sheetmetal work course. The titles of the terminal objectives are Orientation, Shop Machinery and Material, Soldering, Measurements and Layouts, Assigned Shop Projects, and Radial and Triangulation…

Use of a spread sheet to calculate the current-density distribution produced in human and rat models by low-frequency electric fields.

PubMed

Hart, F X

1990-01-01

The current-density distribution produced inside irregularly shaped, homogeneous human and rat models by low-frequency electric fields is obtained by a two-stage finite-difference procedure. In the first stage the model is assumed to be equipotential. Laplace's equation is solved by iteration in the external region to obtain the capacitive-current densities at the model's surface elements. These values then provide the boundary conditions for the second-stage relaxation solution, which yields the internal current-density distribution. Calculations were performed with the Excel spread-sheet program on a Macintosh-II microcomputer. A spread sheet is a two-dimensional array of cells. Each cell of the sheet can represent a square element of space. Equations relating the values of the cells can represent the relationships between the potentials in the corresponding spatial elements. Extension to three dimensions is readily made. Good agreement was obtained with current densities measured on human models with both, one, or no legs grounded and on rat models in four different grounding configurations. The results also compared well with predictions of more sophisticated numerical analyses. Spread sheets can provide an inexpensive and relatively simple means to perform good, approximate dosimetric calculations on irregularly shaped objects.

Dip coating process: Silicon sheet growth development for the large-area silicon sheet task of the low-cost silicon solar array project

NASA Technical Reports Server (NTRS)

Heaps, J. D.; Maciolek, R. B.; Zook, J. D.; Harrison, W. B.; Scott, M. W.; Hendrickson, G.; Wolner, H. A.; Nelson, L. D.; Schuller, T. L.; Peterson, A. A.

1976-01-01

The technical and economic feasibility of producing solar cell quality sheet silicon by dip-coating one surface of carbonized ceramic substrates with a thin layer of large grain polycrystalline silicon was investigated. The dip-coating methods studied were directed toward a minimum cost process with the ultimate objective of producing solar cells with a conversion efficiency of 10% or greater. The technique shows excellent promise for low cost, labor-saving, scale-up potentialities and would provide an end product of sheet silicon with a rigid and strong supportive backing. An experimental dip-coating facility was designed and constructed, several substrates were successfully dip-coated with areas as large as 25 sq cm and thicknesses of 12 micron to 250 micron. There appears to be no serious limitation on the area of a substrate that could be coated. Of the various substrate materials dip-coated, mullite appears to best satisfy the requirement of the program. An inexpensive process was developed for producing mullite in the desired geometry.

The future of spaceborne altimetry. Oceans and climate change: A long-term strategy

NASA Technical Reports Server (NTRS)

Koblinsky, C. J. (Editor); Gaspar, P. (Editor); Lagerloef, G. (Editor)

1992-01-01

The ocean circulation and polar ice sheet volumes provide important memory and control functions in the global climate. Their long term variations are unknown and need to be understood before meaningful appraisals of climate change can be made. Satellite altimetry is the only method for providing global information on the ocean circulation and ice sheet volume. A robust altimeter measurement program is planned which will initiate global observations of the ocean circulation and polar ice sheets. In order to provide useful data about the climate, these measurements must be continued with unbroken coverage into the next century. Herein, past results of the role of the ocean in the climate system is summarized, near term goals are outlined, and requirements and options are presented for future altimeter missions. There are three basic scientific objectives for the program: ocean circulation; polar ice sheets; and mean sea level change. The greatest scientific benefit will be achieved with a series of dedicated high precision altimeter spacecraft, for which the choice of orbit parameters and system accuracy are unencumbered by requirements of companion instruments.

Frustules to fragments, diatoms to dust: How degradation of microfossil shape and microstructures can teach us how ice sheets work

USGS Publications Warehouse

Scherer, R.P.; Sjunneskog, C.M.; Iverson, M.R.; Hooyer, T.S.

2005-01-01

In a laboratory experiment we investigated micro- and nanoscale changes in fossil diatom valves and in the texture of diatomaceous sediments that result from ice sheet overburden and subglacial shearing. Our experiment included compression and shearing of Antarctic diatom-rich sediments in a ring shear device and comparison of experimental samples with natural glacial sediments from the Antarctic continental shelf. The purpose of the experiment is to establish objective criteria for analyzing subglacial processes and interpreting the origin of glacial-geologic features on the Antarctic continental shelf. We find distinct changes resulting from different glacial settings, with respect to whole diatom frustules, diatom micromorphology, and microtextural properties of sedimentary units. By providing constraints on subglacial shearing, these observations of genetically controlled micro- and nanoscale diatom structures and architecture are contributing to the understanding of large-scale glacial processes, aiding the development of models of modern ice sheet processes, and guiding interpretation of past ice sheet configurations. Copyright ?? 2005 American Scientific Publishers. All rights reserved.

Efficacy of a polyurethane dressing versus a soft silicone sheet on hypertrophic scars.

PubMed

Wigger-Albert, W; Kuhlmann, M; Wilhelm, D; Mrowietz, U; Eichhorn, K; Ortega, J; Bredehorst, A; Wilhelm, K-P

2009-05-01

To compare the efficacy and safety of a polyurethane dressing with a silicone sheet in the treatment of hypertrophic scars. Sixty patients participated in this intra-individual 12-week clinical trial. Each scar was divided into two areas, to which the polyurethane dressing and the silicone sheet were randomly allocated. The primary outcome measure was the percentage change in the overall scar index (SI) between baseline and week 12. Secondary outcome measures included changes in skin redness, objectively measured by chromametry, and patients views on the aesthetic outcome of treatment. Both therapies achieved favourable results for all of the above outcome measures. Results were comparable for the primary outcome measure: 29.4% versus 33.7% for the silicone sheet and polyurethane product respectively. The decrease in the overall SI was significantly more pronounced for the polyurethane product after week 4 (5.6% versus 15.8% for the silicone sheet; p<0.0001) and week 8 (20.2% versus 27.1%; p=0.012). Both regimens were associated with a significant reduction in the clinical signs of hypertrophic scars over 12 weeks of treatment. The polyurethane dressing demonstrated a significantly more pronounced reduction in severity of these clinical signs after four and eight weeks of treatment and was better tolerated than the silicone sheet. l This study was funded by Beiersdorf AG. proDERM is an independent research company, and none of the authors have an interest in the sponsors commercial activities.

"Is It the Real Thing?" Cola Lab.

ERIC Educational Resources Information Center

McGuire, Neva; McGraw, Dana

1988-01-01

Introduces an interdisciplinary activity using a cola drink. Describes the lesson plan, including objectives, procedures, evaluation, projects, and conclusions. Provides two laboratory sheets containing problem, hypothesis, materials, procedure, observations, and conclusions, vocabulary table, and data table. (YP)

Contact replacement for NMR resonance assignment.

PubMed

Xiong, Fei; Pandurangan, Gopal; Bailey-Kellogg, Chris

2008-07-01

Complementing its traditional role in structural studies of proteins, nuclear magnetic resonance (NMR) spectroscopy is playing an increasingly important role in functional studies. NMR dynamics experiments characterize motions involved in target recognition, ligand binding, etc., while NMR chemical shift perturbation experiments identify and localize protein-protein and protein-ligand interactions. The key bottleneck in these studies is to determine the backbone resonance assignment, which allows spectral peaks to be mapped to specific atoms. This article develops a novel approach to address that bottleneck, exploiting an available X-ray structure or homology model to assign the entire backbone from a set of relatively fast and cheap NMR experiments. We formulate contact replacement for resonance assignment as the problem of computing correspondences between a contact graph representing the structure and an NMR graph representing the data; the NMR graph is a significantly corrupted, ambiguous version of the contact graph. We first show that by combining connectivity and amino acid type information, and exploiting the random structure of the noise, one can provably determine unique correspondences in polynomial time with high probability, even in the presence of significant noise (a constant number of noisy edges per vertex). We then detail an efficient randomized algorithm and show that, over a variety of experimental and synthetic datasets, it is robust to typical levels of structural variation (1-2 AA), noise (250-600%) and missings (10-40%). Our algorithm achieves very good overall assignment accuracy, above 80% in alpha-helices, 70% in beta-sheets and 60% in loop regions. Our contact replacement algorithm is implemented in platform-independent Python code. The software can be freely obtained for academic use by request from the authors.

1H, 13C, and 15N backbone assignment and secondary structure of the receptor-binding domain of vascular endothelial growth factor.

PubMed Central

Fairbrother, W. J.; Champe, M. A.; Christinger, H. W.; Keyt, B. A.; Starovasnik, M. A.

1997-01-01

Nearly complete sequence-specific 1H, 13C, and 15N resonance assignments are reported for the backbone atoms of the receptor-binding domain of vascular endothelial growth factor (VEGF), a 23-kDa homodimeric protein that is a major regulator of both normal and pathological angiogenesis. The assignment strategy relied on the use of seven 3D triple-resonance experiments [HN(CO)CA, HNCA, HNCO, (HCA)CONH, HN(COCA)HA, HN(CA)HA, and CBCA-(CO)NH] and a 3D 15N-TOCSY-HSQC experiment recorded on a 0.5 mM (12 mg/mL) sample at 500 MHz, pH 7.0, 45 degrees C. Under these conditions, 15N relaxation data show that the protein has a rotational correlation time of 15.0 ns. Despite this unusually long correlation time, assignments were obtained for 94 of the 99 residues; 8 residues lack amide 1H and 15N assignments, presumably due to rapid exchange of the amide 1H with solvent under the experimental conditions used. The secondary structure of the protein was deduced from the chemical shift indices of the 1H alpha, 13C alpha, 13C beta, and 13CO nuclei, and from analysis of backbone NOEs observed in a 3D 15N-NOESY-HSQC spectrum. Two helices and a significant amount of beta-sheet structure were identified, in general agreement with the secondary structure found in a recently determined crystal structure of a similar VEGF construct [Muller YA et al., 1997, Proc Natl Acad Sci USA 94:7192-7197]. PMID:9336848

A high precision instrument to measure angular and binocular deviation introduced by aircraft windscreens by using a shadow casting technique

NASA Astrophysics Data System (ADS)

Shivananju, B. N.; Yamdagni, S.; Vasu, R. M.; Asokan, S.

2012-12-01

Objects viewed through transparent sheets with residual non-parallelism and irregularity appear shifted and distorted. This distortion is measured in terms of angular and binocular deviation of an object viewed through the transparent sheet. The angular and binocular deviations introduced are particularly important in the context of aircraft windscreens and canopies as they can interfere with decision making of pilots especially while landing, leading to accidents. In this work, we have developed an instrument to measure both the angular and binocular deviations introduced by transparent sheets. This instrument is especially useful in the qualification of aircraft windscreens and canopies. It measures the deviation in the geometrical shadow cast by a periodic dot pattern trans-illuminated by the distorted light beam from the transparent test specimen compared to the reference pattern. Accurate quantification of the shift in the pattern is obtained by cross-correlating the reference shadow pattern with the specimen shadow pattern and measuring the location of the correlation peak. The developed instrument is handy to use and computes both angular and binocular deviation with an accuracy of less than ±0.1 mrad (≈0.036 mrad) and has an excellent repeatability with an error of less than 2%.

Two-dimensional sup 1 H nuclear magnetic resonance study of AaH IT, an anti-insect toxin from the scorpion Androctonus australis Hector. Sequential resonance assignments and folding of the polypeptide chain

DOE Office of Scientific and Technical Information (OSTI.GOV)

Darbon, H.; Weber, C.; Braun, W.

1991-02-19

Sequence-specific nuclear magnetic resonance assignments for the polypeptide backbone and for most of the amino acid side-chain protons, as well as the general folding of AaH IT, are described. AaH IT is a neurotoxin purified from the venom of the scorpion Androctonus australis Hector and is specifically active on the insect nervous system. The secondary structure and the hydrogen-bonding patterns in the regular secondary structure elements are deduced from nuclear Overhauser effects and the sequence locations of the slowly exchanging amide protons. The backbone folding is determined by distance geometry calculations with the DISMAN program. The regular secondary structure includesmore » two and a half turns of {alpha}-helix running from residues 21 to 30 and a three-stranded antiparallel {beta}-sheet including peptides 3-5, 34-38, and 41-46. Two tight turns are present, one connecting the end of the {alpha}-helix to an external strand of the {beta}-sheet, i.e., turn 31-34, and another connecting this same strand to the central one, i.e., turn 38-41. The differences in the specificity of these related proteins, which are able to discriminate between mammalian and insect voltage-dependent sodium channels of excitable tissues, are most probably brought about by the position of the C-terminal peptide with regard to a hydrophobic surface common to all scorpion toxins examined thus far. Thus, the interaction of a given scorpion toxin with its receptor might well be governed by the presence of this solvent-exposed hydrophobic surface, whereas adjacent areas modulate the specificity of the interaction.« less

Real life working shift assignment problem

NASA Astrophysics Data System (ADS)

Sze, San-Nah; Kwek, Yeek-Ling; Tiong, Wei-King; Chiew, Kang-Leng

2017-07-01

This study concerns about the working shift assignment in an outlet of Supermarket X in Eastern Mall, Kuching. The working shift assignment needs to be solved at least once in every month. Current approval process of working shifts is too troublesome and time-consuming. Furthermore, the management staff cannot have an overview of manpower and working shift schedule. Thus, the aim of this study is to develop working shift assignment simulation and propose a working shift assignment solution. The main objective for this study is to fulfill manpower demand at minimum operation cost. Besides, the day off and meal break policy should be fulfilled accordingly. Demand based heuristic is proposed to assign working shift and the quality of the solution is evaluated by using the real data.

Flexible thermal apparatus for mounting of thermoelectric cooler

NASA Technical Reports Server (NTRS)

Jones, Jack A. (Inventor); Petrick, S. Walter (Inventor); Bard, Steven (Inventor)

1991-01-01

A flexible heat transfer apparatus used to flexibly connect and thermally couple a thermoelectric cooler to an object to be cooled is disclosed. The flexible heat transfer apparatus consists of a pair of flexible corrugated sheets made from high thermal conductivity materials such as copper, aluminum, gold, or silver. The ridges of the corrugated sheets are oriented perpendicular to one another and bonded sandwich-fashion between three plates to define an upper section and a lower section. The upper section provides X flexure, the lower section provides Y flexure, and both sections together provide Z flexure.

Capillary origami: spontaneous wrapping of a droplet with an elastic sheet.

PubMed

Py, Charlotte; Reverdy, Paul; Doppler, Lionel; Bico, José; Roman, Benoît; Baroud, Charles N

2007-04-13

The interaction between elasticity and capillarity is used to produce three-dimensional structures through the wrapping of a liquid droplet by a planar sheet. The final encapsulated 3D shape is controlled by tailoring the initial geometry of the flat membrane. Balancing interfacial energy with elastic bending energy provides a critical length scale below which encapsulation cannot occur, which is verified experimentally. This length is found to depend on the thickness as h3/2, a scaling favorable to miniaturization which suggests a new way of mass production of 3D micro- or nanoscale objects.

Laser-zone growth in a Ribbon-To-Ribbon (RTR) process, silicon sheet growth development for the large area silicon sheet task of the low cost silicon solar array project

NASA Technical Reports Server (NTRS)

Gurtler, R. W.; Baghdadi, A.

1976-01-01

The objective of this research is to fully investigate the Ribbon-To-Ribbon (R-T-R) approach to silicon ribbon growth. Initial work has concentrated on modification and characterization of an existing R-T-R apparatus. In addition, equipment for auxiliary heating of the melt is being evaluated and acquired. Modification of the remote viewing system and mechanical staging are nearly complete. Characterization of the laser and other components is in progress and several auxiliary heating techniques are being investigated.

Transplantation of Scaffold-Free Cartilage-Like Cell-Sheets Made from Human Bone Marrow Mesenchymal Stem Cells for Cartilage Repair: A Preclinical Study.

PubMed

Itokazu, Maki; Wakitani, Shigeyuki; Mera, Hisashi; Tamamura, Yoshihiro; Sato, Yasushi; Takagi, Mutsumi; Nakamura, Hiroaki

2016-10-01

The object of this study was to determine culture conditions that create stable scaffold-free cartilage-like cell-sheets from human bone marrow-derived mesenchymal stem cells (hBMSCs) and to assess their effects after transplantation into osteochondral defects in nude rats. (Experiment 1) The hBMSCs were harvested from 3 males, the proliferative and chondrogenic capacities were assessed at passage 1, and the cells were expanded in 3 different culture conditions: (1) 5% fetal bovine serum (FBS), (2) 10% FBS, and (3) 5% FBS with fibroblast growth factor 2 (FGF-2). The cells were harvested and made chondrogenic pellet culture. The cell proliferation rate, glycosaminoglycan/DNA ratio, and safranin-O staining intensity of pellets cultured condition 3 were higher than those of conditions 1 and 2. (Experiment 2) The hBMSCs were expanded and passaged 3 times under culture condition 3, and fabricate the cell-sheets in chondrogenic medium either with or without FBS. The cell-sheets fabricated with FBS maintained their size with flat edges. (Experiment 3) The cell-sheets were transplanted into osteochondral defects in nude rats. Histological analysis was performed at 2, 4, and 12 weeks after surgery. The osteochondral repair was better after sheet transplantation than in the control group and significantly improved Wakitani score. Immunostaining with human-specific vimentin antibody showed that the transplanted cells became fewer and disappeared at 12 weeks. These results indicate that culture with FGF-2 may help to quickly generate sufficient numbers of cells to create stable and reliable scaffold-free cartilage-like cell-sheets, which contribute to the regeneration of osteochondral defects.

Ice_Sheets_CCI: Essential Climate Variables for the Greenland Ice Sheet

NASA Astrophysics Data System (ADS)

Forsberg, R.; Sørensen, L. S.; Khan, A.; Aas, C.; Evansberget, D.; Adalsteinsdottir, G.; Mottram, R.; Andersen, S. B.; Ahlstrøm, A.; Dall, J.; Kusk, A.; Merryman, J.; Hvidberg, C.; Khvorostovsky, K.; Nagler, T.; Rott, H.; Scharrer, M.; Shepard, A.; Ticconi, F.; Engdahl, M.

2012-04-01

As part of the ESA Climate Change Initiative (www.esa-cci.org) a long-term project "ice_sheets_cci" started January 1, 2012, in addition to the existing 11 projects already generating Essential Climate Variables (ECV) for the Global Climate Observing System (GCOS). The "ice_sheets_cci" goal is to generate a consistent, long-term and timely set of key climate parameters for the Greenland ice sheet, to maximize the impact of European satellite data on climate research, from missions such as ERS, Envisat and the future Sentinel satellites. The climate parameters to be provided, at first in a research context, and in the longer perspective by a routine production system, would be grids of Greenland ice sheet elevation changes from radar altimetry, ice velocity from repeat-pass SAR data, as well as time series of marine-terminating glacier calving front locations and grounding lines for floating-front glaciers. The ice_sheets_cci project will involve a broad interaction of the relevant cryosphere and climate communities, first through user consultations and specifications, and later in 2012 optional participation in "best" algorithm selection activities, where prototype climate parameter variables for selected regions and time frames will be produced and validated using an objective set of criteria ("Round-Robin intercomparison"). This comparative algorithm selection activity will be completely open, and we invite all interested scientific groups with relevant experience to participate. The results of the "Round Robin" exercise will form the algorithmic basis for the future ECV production system. First prototype results will be generated and validated by early 2014. The poster will show the planned outline of the project and some early prototype results.

Stationary Engineering Science Manual--3.

ERIC Educational Resources Information Center

Steingress, Frederick M.; And Others

This manual provides in-depth coverage of topics related to boiler operations. The assignments contain an objective, descriptive information, reference sources, procedures, and assignments. Sixteen units are provided and address topics such as: (1) steam engineering concepts; (2) boiler fittings; (3) feed-water, steam, and combustion accessories;…

Grouping puts figure-ground assignment in context by constraining propagation of edge-assignment

PubMed Central

Brooks, Joseph L.; Driver, Jon

2010-01-01

Figure-ground organization involves assignment of edges to a figural shape on one or the other side of each dividing edge. Established visual cues for edge-assignment primarily concern relatively local rather than contextual factors. Here we show that assignment for a locally-unbiased edge can be affected by assignment of a remote contextual edge that has its own locally-biased assignment. We find that such propagation of edge-assignment from the biased remote context occurs only when the biased and unbiased edges are grouped. This new principle, whereby grouping constrains propagation of figural edge-assignment, emerges from both subjective reports and from an objective short-term edge-matching task. It generalizes from moving displays involving grouping by common fate and collinearity, to static displays with grouping by similarity of edge-contrast polarity, or apparent occlusion. Our results identify a new contextual influence upon edge-assignment. They also identify a new mechanistic relation between grouping and figure-ground processes, whereby grouping between remote elements can constrain propagation of edge-assignment between those elements. PMID:20436200

In vitro fabrication of functional three-dimensional tissues with perfusable blood vessels

PubMed Central

Sekine, Hidekazu; Shimizu, Tatsuya; Sakaguchi, Katsuhisa; Dobashi, Izumi; Wada, Masanori; Yamato, Masayuki; Kobayashi, Eiji; Umezu, Mitsuo; Okano, Teruo

2013-01-01

In vitro fabrication of functional vascularized three-dimensional tissues has been a long-standing objective in the field of tissue engineering. Here we report a technique to engineer cardiac tissues with perfusable blood vessels in vitro. Using resected tissue with a connectable artery and vein as a vascular bed, we overlay triple-layer cardiac cell sheets produced from coculture with endothelial cells, and support the tissue construct with media perfused in a bioreactor. We show that endothelial cells connect to capillaries in the vascular bed and form tubular lumens, creating in vitro perfusable blood vessels in the cardiac cell sheets. Thicker engineered tissues can be produced in vitro by overlaying additional triple-layer cell sheets. The vascularized cardiac tissues beat and can be transplanted with blood vessel anastomoses. This technique may create new opportunities for in vitro tissue engineering and has potential therapeutic applications. PMID:23360990

Catalogue of X-Ray Texture Data for Al-Cu-Li Alloy 1460, 2090, 2096 and 2195 Near-Net-Shape Extrusions, Sheet and Plate

NASA Technical Reports Server (NTRS)

Hales, Stephen J.; Hafley, Robert A.; Alexa, Joel A.

1998-01-01

The effect of crystallographic texture on the mechanical properties of near-net-shape extrusions is of major interest ff these products are to find application in launch vehicle or aircraft structures. The objective of this research was to produce a catalogue containing quantitative texture information for extruded product, sheet and plate. The material characterized was extracted from wide, integrally stiffened panels fabricated from the Al-Cu-Li alloys 1460, 2090, 2096 and 2195. The textural characteristics of sheet and plate products of the same alloys were determined for comparison purposes. The approach involved using X-ray diffraction to generate pole figures in combination with orientation distribution function analysis. The data were compiled as a function of location in the extruded cross-sections and the variation in the major deformation- and recrystallization-related texture components was identified.

Dip-coating process: Silicon sheet growth development for the large-area silicon sheet task of the low-cost silicon solar array project

NASA Technical Reports Server (NTRS)

Zook, J. D.; Heaps, J. D.; Maciolek, R. B.; Koepke, B. G.; Gutter, C. D.; Schuldt, S. B.

1977-01-01

The objective of this research program is to investigate the technical and economic feasibility of producing solar-cell-quality sheet silicon by coating one surface of carbonized ceramic substrates with a thin layer of large-grain polycrystalline silicon from the melt. The past quarter demonstrated significant progress in several areas. Seeded growth of silicon-on-ceramic (SOC) with an EFG ribbon seed was demonstrated. Different types of mullite were successfully coated with silicon. A new method of deriving minority carrier diffusion length, L sub n from spectral response measurements was evaluated. ECOMOD cost projections were found to be in good agreement with the interim SAMIS method proposed by JPL. On the less positive side, there was a decrease in cell performance which we believe to be due to an unidentified source of impurities.

TESS Objects of Interest

NASA Astrophysics Data System (ADS)

Guerrero, Natalia; Glidden, Ana; Fausnaugh, Michael; TESS Team

2018-01-01

We describe the search for TESS Objects of Interest (TOIs), led by the MIT branch of the TESS Science Office (TSO). TSO has developed a tool called TESS Exoplanet Vetter (TEV) to facilitate this process. Individuals independently examine data validation products for each target and assign a category to the object: planet candidate, eclipsing binary, other astrophysical, stellar variability, or instrument noise/systematic. TEV assigns a preliminary follow-up priority designation to each object and allows for modification when final dispositions are decided on in a group setting. When all targets are vetted, TEV exports a catalogue of TOIs which is delivered to the TESS Follow-Up Observing Program (TFOP), working with ExoFOP-TESS, and made publicly available on the official TESS website and the Mikulski Archive for Space Telescopes (MAST).

Macro-magnetic Modeling of the ARL Microelectromechanical System (MEMS) Flux Concentrator

DTIC Science & Technology

2011-09-01

are drawn as solid pieces and assigned the material properties of permalloy (nickel-iron [ NiFe ]) with a permeability of 5,000 as that is a value...energy densities, and saturation. The modeling process consists of drawing the objects of interest, assigning properties (coercivity, permeability...that is readily achieved in thin films of the material. The material properties assigned to this background are those of a vacuum, with a relative

Turbidite pathways in Cascadia Basin and Tufts abyssal plain, Part A, Astoria Channel, Blanco Valley, and Gorda Basin

USGS Publications Warehouse

Wolf, Stephen C.; Hamer, Michael R.

1999-01-01

This open-file report was prepared in support of the USGS Earthquake Hazards of Cascadia Project. The primary objective of this phase of the project is to determine recurrence intervals of turbidites in Cascadia basin-floor channel systems and evaluate implications of this event record for the paleoseismic history of the Cascadia subduction zone. The purpose of this study is to determine whether the canyon/channel systems themselves are blocked or deformed in such a way that the downstream turbidite stratigraphy might be biased. To accomplish this investigation approximately 7500 kilometers of pre-existing 3.5 KHz seismic data were evaluated to determine the direction and extent of the Astoria Channel/pathway system, which originates at the base of the Astoria Fan. Additionally, distribution and thickness of turbidite sediment sequences were determined along each identified pathway. Bathymetery and distance were used to determine gradients along the main pathway axis and for each of the secondary pathways that feed into it. Channel pathways were identified on the basis of channel phyisiography, where visible at the seafloor, subbottom channel configuration, and acoustic packets of sediments that might represent turbidite deposits. A principal result of this study is that the Astoria Channel/pathway extends continuously from the base of the Astoria Fan southward along the base of the continental slope through the Blanco Valley, then heads southwestward through the Gorda Basin and into the region of the Escanaba Trough. Additionally it was determined that the Astoria Channel is filled and basically buried for it's full length south of 44 degrees latitude. The 44 North Slump, as defined by Goldfinger (1999, see Map 3 ref.), may have been instrumental in blocking the pathway and thus contributed to the filling of the channel/pathway. Sheets 1 and 2 show the Astoria and secondary turbidite pathways highlighted in blue. Ship survey tracklines are shown for the area studied; they are time and date coded, and color keyed to each ship ID data base listed at the bottom of each sheet. The first letter in the cruise ID is an abbreviation letter for the ship name, the following numbers represent the consecutive cruise number of that year, followed by the year number. The letters at the end of the ID represent the survey area, ie. NC- northern California, NP- north Pacific. Locations of selected sample seismic sections illustrated on sheets 3-5 also are shown. Scales for each of the sheets are the same as for sheets 3-5, which allows for overlaying of track data onto the interpretations shown on Maps A-C. Sheets 3 (MAP A), 4 (MAP B), and 5 (MAP C) show channel pathway location, bathymetric depth based on the USGS COW data base (Ca/Or/Wa), pathway morphology, and thickness of turbidite sediment fill at various locations. The interpreted turbidite sediments are color highlighted on the selected seismic sections to differentiate them from the typical deep sea sediments below and to the side of the turbidite pathways. Thickness of sediment fill, in meters, is shown along major pathways in white circular highlights. The data and interpretations rest on a background of USGS GLORIA side scan sonar imagery (1984) to illustrate the relationship of pathway position to sub sea features. Channel distance points are plotted along channel centerlines at 20,000 m intervals. These points begin at the start of each interpreted channel pathway. A bathymetric depth was assigned to each distance point. These data points were then used to construct channel gradient curves for the Astoria, Eel, Bear Valley, and Mendocino channel pathways. These gradients are plotted on sheet 6 of this report and illustrate the similarities and differences between each of the pathways. Sheet 7 shows various views of the Mendocino/Mattole Canyon heads as an example of useful derivative information of the Seabeam bathymetric data. These views illustrate that the Mendocino pathway probably was directed from it's canyon mouth, to the northwest at an earlier time, but was diverted to the west along the base of the Mendocino Ridge by a major fault event in the recent past. Offset of the southwest channel wall is readily evident in views B and D. This apparent disruption complicates the turbidite history of the Mendocino pathway.

Frequency assignments for HFDF receivers in a search and rescue network

NASA Astrophysics Data System (ADS)

Johnson, Krista E.

1990-03-01

This thesis applies a multiobjective linear programming approach to the problem of assigning frequencies to high frequency direction finding (HFDF) receivers in a search-and-rescue network in order to maximize the expected number of geolocations of vessels in distress. The problem is formulated as a multiobjective integer linear programming problem. The integrality of the solutions is guaranteed by the totally unimodularity of the A-matrix. Two approaches are taken to solve the multiobjective linear programming problem: (1) the multiobjective simplex method as implemented in ADBASE; and (2) an iterative approach. In this approach, the individual objective functions are weighted and combined in a single additive objective function. The resulting single objective problem is expressed as a network programming problem and solved using SAS NETFLOW. The process is then repeated with different weightings for the objective functions. The solutions obtained from the multiobjective linear programs are evaluated using a FORTRAN program to determine which solution provides the greatest expected number of geolocations. This solution is then compared to the sample mean and standard deviation for the expected number of geolocations resulting from 10,000 random frequency assignments for the network.

The Pleistocene evolution of the East Antarctic Ice Sheet in the Prydz bay region: Stable isotopic evidence from ODP Site 1167

USGS Publications Warehouse

Theissen, K.M.; Dunbar, R.B.; Cooper, A. K.; Mucciarone, D.A.; Hoffmann, D.

2003-01-01

Ocean Drilling Program Leg 188, Prydz Bay, East Antarctica is part of a larger initiative to explore the Cenozoic history of the Antarctic Ice Sheet through direct drilling and sampling of the continental margins. In this paper, we present stable isotopic results from Ocean Drilling Program (ODP) Site 1167 located on the Prydz Channel Trough Mouth Fan (TMF), the first Antarctic TMF to be drilled. The foraminifer-based ??18O record is interpreted along with sedimentary and downhole logging evidence to reconstruct the Quaternary glacial history of Prydz Bay and the adjacent Lambert Glacier Amery Ice Shelf System (LGAISS). We report an electron spin resonance age date of 36. 9 ?? 3.3 ka at 0.45 m below sea floor and correlate suspected glacial-interglacial cycles with the global isotopic stratigraphy to improve the chronology for Site 1167. The ??18O record based on planktonic (Neogloboquadrina pachyderma (s.)) and limited benthic results (Globocassidulina crassa), indicates a trend of ice sheet expansion that was interrupted by a period of reduced ice volume and possibly warmer conditions during the early-mid-Pleistocene (0.9-1.38 Ma). An increase in ?? 18O values after ??? 900 ka appears to coincide with the mid-Pleistocene climate transition and the expansion of the northern hemisphere ice sheet. The ??18O record in the upper 50 m of the stratigraphic section indicates as few as three glacial-interglacial cycles, tentatively assigned as marine isotopic stages (MIS) 16-21, are preserved since the Brunhes/Matuyama paleomagnetic reversal (780 ka). This suggests that there is a large unconformity near the top of the section and/or that there may have been few extreme advances of the ice sheet since the mid-Pleistocene climate transition resulting in lowered sedimentation rates on the Prydz Channel TMF. The stable isotopic record from Site 1167 is one of the few available from the area south of the Antarctic Polar Front that has been linked with the global isotopic stratigraphy. Our results suggest the potential for the recovery of useful stable isotopic records in other TMFs. ?? 2003 Elsevier B.V. All rights reserved.

41 CFR 109-38.5105 - Motor vehicle local use objectives.

Code of Federal Regulations, 2011 CFR

2011-01-01

... performance of daily work assignments, would have uniquely tailored use objectives, different from those set... future motor vehicle requirements, must be established and documented by the Organizational Motor Equipment Fleet Manager. The objectives should take into consideration past performance, future requirements...

Nuclear Data Sheets for A=243

DOE Office of Scientific and Technical Information (OSTI.GOV)

Nesaraja, Caroline D; McCutchan, Elizabeth A.

2014-09-30

We present available information pertaining to the nuclear structure of all nuclei with mass numbers A=243. Various decay and reaction data are evaluated and compared. Adopted data, levels, spin, parity and configuration assignments are given. When there are insufficient data, expected values from systematics of nuclear properties or/and theoretical calculations are quoted. Unexpected or discrepant experimental results are also noted. A summary and compilation of the discovery of various isotopes in this mass region is given in 2013Fr02 ( 243Np, 243Pu, 243Am, 243Cm, 243Bk, and 243Cf), 2011Me01 ( 243Es), and 2013Th02 ( 243Fm).

"The Chemicals Project": Connecting General Chemistry to Students' Lives

NASA Astrophysics Data System (ADS)

Stout, Roland

2000-10-01

"The Chemicals Project" described here strives to bring freshman chemistry alive for students by emphasizing its connection to the real world and to their own lives and experiences. Its major assignments deal with chemical phobias, recognizing the chemicals found in everyday life and chemical hazards (using Material Data Safety Sheets). The project is described in a cooperative learning format, employs portfolio grading, and includes a significant writing component. Ways of linking this project with the course lecture and student evaluations of the project are described. The bottom line: pre- and post-testing shows that it works. The Chemicals Project brings chemistry alive for students.

Images of intravitreal objects projected onto posterior surface of model eye.

PubMed

Kawamura, Ryosuke; Shinoda, Kei; Inoue, Makoto; Noda, Toru; Ohnuma, Kazuhiko; Hirakata, Akito

2013-11-01

To try to recreate the images reported by patients during vitreous surgery in a model eye. A fluid-filled model eye with a posterior frosted translucent surface which corresponded to the retina was used. Three holes were made in the model eye through which an endoillumination pipe and intraocular forceps could be inserted. A thin plastic sheet simulating an epiretinal membrane and an intraocular lens (IOL) simulating a dislocated IOL were placed on the retina. The images falling on the posterior surface were photographed from the rear. The images seen through the surgical microscope were also recorded. The images from the rear were mirror images of those seen through the surgical microscope. Intraocular instruments were seen as black shafts from the rear. When the plastic sheet was picked up, the tip of the forceps was seen more sharply on the posterior surface. The images of the dislocated IOL from the posterior were similar to that seen through the surgical microscope, including the yellow optics and blue haptics. Intravitreal objects can form images on the surface of a model eye. Objects located closer to the surface are seen more sharply, and the colour of the objects can be identified. © 2013 Acta Ophthalmologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.

Residential Carpentry.

ERIC Educational Resources Information Center

Hendrix, Laborn J.

This curriculum guide provides instructional materials for a course to train carpenters who will make careers in construction. It includes 6 sections and 21 instructional units. Each unit of instruction consists of eight basic components: performance objectives, teacher activities, information sheets (content essential for meeting the cognitive…

Are we reaching the target audience? Evaluation of a fish fact sheet.

PubMed

Burger, J; Waishwell, L

2001-09-28

According to the US Environmental Protection Agency, over 16% of freshwater lakes and 7% of the rivers are under some sort of fish consumption advisory because of the presence of toxic chemicals. There is considerable interest in the issuing of information, advisories, and fact sheets concerning the consumption of wild-caught fish from contaminated waters, and in the actual consumption patterns of subsistence and recreational anglers. Despite the large number of consumption advisories issued by state agencies, there is little information on how these advisories, or other forms of risk communication, are perceived by target audiences, notably fishermen and women of child-bearing age. The states of South Carolina and Georgia issue consumption advisories for fish from the Savannah River, among other sites. To gain a greater insight into the perception of anglers about a supplemental fish fact sheet jointly developed by South Carolina, Georgia, federal agencies, and the Consortium for Risk Evaluation with Stakeholder Participation, we interviewed fisherman along the Savannah River. The objectives were to determine: (1) whether they had previously read the Fish Fact Sheet or had heard about the consumption advisories; (2) what major message they obtained from the sheet; (3) who they felt the fact sheet was aimed at, and who should get the Fish Fact Sheet; (4) who should be concerned about health risks from consuming the fish; and (5) the best method of disseminating such information. We interviewed 92 fishermen (37% black, 62% white) during the fishing season of 1999. Half had heard some information about consumption advisories, mainly from the media (64%). The study concluded that there were no ethnic differences in whether they had heard about the advisories, understood the major message of the fact sheet, felt they could reduce their risk from consuming the fish, or felt that it made a difference which agency issued the fact sheet. There were significant ethnic differences in the ways people thought the risk from eating fish could be reduced, sources of information about the risks from consuming fish, and what other information they would like about the risks associated with contaminated fish.

Shaped-Based Recognition of 3D Objects From 2D Projections

DTIC Science & Technology

2006-12-01

functions for a typical minimization by the graduated assignment algorithm. (The solid line is E , which uses the Euclid- ean distances to the nearest...of E and E0 generally decrease during the optimiza- tion process, but they can also rise because of changes in the assignment variables Mjk...m+ 1)× (n+ 1) match matrix M that minimizes the objective function E = mX j=1 nX k=1 Mjk ³ d (T (lj) , l 0 k) 2 − δ2 ´ . (7) M defines the

Early Spacelab missions

NASA Technical Reports Server (NTRS)

Pace, R. E., Jr.; Craft, H. G., Jr.

1977-01-01

NASA has issued payload flight assignments for the first three Spacelab missions. The first two of these missions will have dual objectives, that of verifying Spacelab system performance and accomplishing meaningful space research. The first of these missions will be a joint NASA and ESA mission with a multidisciplinary payload. The second mission will verify a different Spacelab configuration while addressing the scientific disciplines of astrophysics. The third assigned mission will concentrate on utilizing the capabilities of Spacelab to perform meaningful experiments in space applications, primarily space processing. The paper describes these missions with their objectives, planned configuration and accommodation.

Microstructural investigations of the trimmed edge of DP980 steel sheets

NASA Astrophysics Data System (ADS)

Bhattacharya, S.; Green, D. E.; Sohmshetty, R.; Alpas, A. T.

2017-10-01

In order to reduce vehicle weight while maintaining crashworthiness, advanced high strength steels (AHSSs), such as DP980, are extensively used for manufacturing automotive body components. During trimming operations, the high tensile strength of DP980 sheets tends to cause damage of the trim edge of D2 die inserts, which result in deterioration of the edge quality. The objective of this work is to study the damage microstructures at the trimmed edge of DP980 steel sheets as a function of the number of trimming cycles. A mechanical press equipped with AISI D2 tool steel inserts was used to continuously trim 1.4 mm thick sheets of DP980 at a rate of 30 strokes/min. Cross-sectional SEM images of the trimmed edges revealed that the sheared edge quality of the DP980 sheets decreased, indicated by an increase in the burr width, with an increase in the number of trims from 40,000 to 70,000. Plastic strains were estimated using the displacements of the martensite plates within plastic flow fields of ferrite. Site-specific cross-sectional TEM samples, excised from the trimmed edge using the in-situ `lift-out' technique by focused ion-beam (FIB)-milling, revealed cracking at the ferrite/martensite interfaces after 70,000 cycles indicating an increase in the depth of deformation zone possibly due to trimming with a chipped and blunted die edge.

Detection of defects in formed sheet metal using medial axis transformation

NASA Astrophysics Data System (ADS)

Murmu, Naresh C.; Velgan, Roman

2003-05-01

In the metal forming processes, the sheet metals are often prone to various defects such as thinning, dents, wrinkles etc. In the present manufacturing environments with ever increasing demand of higher quality, detecting the defects of formed sheet metal using an effective and objective inspection system is the foremost norm to remain competitive in market. The defect detection using optical techniques aspire to satisfy its needs to be non-contact and fast. However, the main difficulties to achieve this goal remain essentially on the development of efficient evaluation technique and accurate interpretation of extracted data. The defect like thinning is detected by evaluating the deviations of the thickness in the formed sheet metal against its nominal value. The present evaluation procedure for determination of thickness applied on the measurements data is not without deficiency. To improve this procedure, a new evaluation approach based on medial axis transformation is proposed here. The formed sheet metals are digitized using fringe projection systems in different orientations, and afterwards registered into one coordinate frame. The medial axis transformation (MAT) is applied on the point clouds, generating the point clouds of MAT. This data is further processed and medial surface is determined. The thinning defect is detected by evaluating local wall thickness and other defects like wrinkles are determined using the shape recognition on the medial surface. The applied algorithm is simple, fast and robust.

The Decisional Balance Sheet to Promote Healthy Behavior Among Ethnically Diverse Older Adults

PubMed Central

Geller, Karly S.; Mendoza, Ilora D.; Timbobolan, Jasah; Montjoy, Holly L.; Nigg, Claudio R.

2012-01-01

Objective The rising health care costs and increasing older adult population in the United States make preventive medicine for this age group especially crucial. Regular physical activity and fruit and vegetable consumption may prevent or delay the onset of many chronic conditions that are common among older adults. The decisional balance sheet is a promotional tool targeting the perceived pros and cons of behavior adoption. The current study tested the efficiency and effectiveness of a single-day decisional balance sheet program, targeting increased physical activity and fruit and vegetable intake among older adults. Design and Sample Participating adults (N = 21, age = 72.2) who represented a diverse population in Hawaii (Japanese = 5, Filipino = 4, Caucasian = 4, Native American = 1, Native Hawaiian = 1, Hispanic = 1, and Others = 5) were recruited from housing communities and randomized to a decisional balance sheet program adapted for physical activity or fruit and vegetable consumption. Measures Physical activity was assessed using the International Physical Activity Questionnaire (IPAQ) short form, and daily fruit and vegetable intake with the National Health and Nutrition Examination Survey single item instrument. Baseline and follow-up data were collected. Results Both programs were implemented efficiently, and participants in both groups improved their daily physical activity. The decisional balance sheet for fruit and vegetable consumption appeared less effective. Conclusions Specific suggestions for similar programs are reported. PMID:22512425

Modeling the fracture of ice sheets on parallel computers.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Waisman, Haim; Bell, Robin; Keyes, David

2010-03-01

The objective of this project is to investigate the complex fracture of ice and understand its role within larger ice sheet simulations and global climate change. At the present time, ice fracture is not explicitly considered within ice sheet models due in part to large computational costs associated with the accurate modeling of this complex phenomena. However, fracture not only plays an extremely important role in regional behavior but also influences ice dynamics over much larger zones in ways that are currently not well understood. Dramatic illustrations of fracture-induced phenomena most notably include the recent collapse of ice shelves inmore » Antarctica (e.g. partial collapse of the Wilkins shelf in March of 2008 and the diminishing extent of the Larsen B shelf from 1998 to 2002). Other fracture examples include ice calving (fracture of icebergs) which is presently approximated in simplistic ways within ice sheet models, and the draining of supraglacial lakes through a complex network of cracks, a so called ice sheet plumbing system, that is believed to cause accelerated ice sheet flows due essentially to lubrication of the contact surface with the ground. These dramatic changes are emblematic of the ongoing change in the Earth's polar regions and highlight the important role of fracturing ice. To model ice fracture, a simulation capability will be designed centered around extended finite elements and solved by specialized multigrid methods on parallel computers. In addition, appropriate dynamic load balancing techniques will be employed to ensure an approximate equal amount of work for each processor.« less

Credit assignment between body and object probed by an object transportation task.

PubMed

Kong, Gaiqing; Zhou, Zhihao; Wang, Qining; Kording, Konrad; Wei, Kunlin

2017-10-17

It has been proposed that learning from movement errors involves a credit assignment problem: did I misestimate properties of the object or those of my body? For example, an overestimate of arm strength and an underestimate of the weight of a coffee cup can both lead to coffee spills. Though previous studies have found signs of simultaneous learning of the object and of the body during object manipulation, there is little behavioral evidence about their quantitative relation. Here we employed a novel weight-transportation task, in which participants lift the first cup filled with liquid while assessing their learning from errors. Specifically, we examined their transfer of learning when switching to a contralateral hand, the second identical cup, or switching both hands and cups. By comparing these transfer behaviors, we found that 25% of the learning was attributed to the object (simply because of the use of the same cup) and 58% of the learning was attributed to the body (simply because of the use of the same hand). The nervous system thus seems to partition the learning of object manipulation between the object and the body.

Effects of structured versus non-structured learning on achievement and attitudes of fifth graders in a public aquarium

NASA Astrophysics Data System (ADS)

Kafka, Merryl Audrey

The investigator analyzed the main effect of a structured-learning experience in an informal setting, as well as interactions between the students' learning-style variations toward the element of structure and the imposed instructional conditions. The subjects consisted of 170 students enrolled in two public schools located in Brooklyn, New York. The students were predominantly a White multi-ethnic population consisting of 118 Caucasians, 25 Hispanics, 24 Asians, and 3 African-Americans. Three randomly assigned classes (n = 81) were provided trip sheets, which directed students on how to learn new information with written questions and directives. Three randomly assigned non-structured classes (n = 89) experienced the same exhibit in a free-form manner. Science-based criterion-referenced pre- and posttests were administered, in addition to Learning Style Inventories (Dunn, Dunn, & Price, 1996) and a modified Semantic Differential Scale (Pizzo, 1981), which was used to measure attitudinal levels. The non-structured group had access to similar content information in the form of exhibit graphics, but apparently they chose not to read it as carefully or engage in the information-seeking process as intensely as the students equipped with trip sheets. Analysis of covariance (ANCOVA) indicated that a structured-learning experience produced significantly higher science-achievement test scores than in a non-structured-learning experience (p = .0001). In addition, there was no single learning-style variation (preference, aversion, or no preference) to structure that produced significantly higher gains than another. Furthermore, attitudinal scores were not significantly different between structured and non-structured groups, as well as among homogeneous subsets of students with learning-style variations that matched, mismatched, or indicated no-preferenced positions on the element of structure. Hence, a moderate amount of structure resulted in academic gains without diminishing attitudinal scores. The fact that students' learning-style variations for sociological, design, and perceptual preferences were simultaneously accommodated in this setting may have contributed to the overall positive effects of this structure-based intervention. The diversified teaching resources of the exhibit and the sense of self-empowerment in a student-directed environment may have elevated students' attitudes regardless of their learning-style need for structure. The students' acceptance of a trip sheet that promoted the understanding of science concepts may have contributed to academic success.

The Orthographic Norm in Secondary School Students' Written Assignments

ERIC Educational Resources Information Center

Ðordev, Ivana

2016-01-01

This paper presents the results of research conducted with the primary objective to determine in which areas secondary school students usually make orthographic mistakes when writing (official) written assignments. Starting from the hypothesis that the punctuation writing of whole and split words are areas in which secondary school students…

Evaluation of a School-Based Teen Obesity Prevention Minimal Intervention

ERIC Educational Resources Information Center

Abood, Doris A.; Black, David R.; Coster, Daniel C.

2008-01-01

Objective: A school-based nutrition education minimal intervention (MI) was evaluated. Design: The design was experimental, with random assignment at the school level. Setting: Seven schools were randomly assigned as experimental, and 7 as delayed-treatment. Participants: The experimental group included 551 teens, and the delayed treatment group…

76 FR 81295 - Cost Accounting Standards: Cost Accounting Standards 412 and 413-Cost Accounting Standards...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-27

... accounting standards governing measurement, assignment, and allocation of costs to contracts with the United... contracting parties; Measurement of pension costs must be objectively verifiable; Accounting rules must keep... cost accounting that preclude their use for the appropriate measurement, assignment and allocation of...

Foods and Nutrition. Student Modules and Instructor's Guide.

ERIC Educational Resources Information Center

South Carolina State Dept. of Education, Columbia. Office of Vocational Education.

These 64 performance-based instructional modules are for the home economics content area of food and nutrition. Each module is composed of an introduction for the student, a performance objective, a variety of learning activities (reading assignments, tasks, written assignments), content information, a student self-check, recommended references,…

Merchandise Display, a Distributive Education Manual and Answer Book.

ERIC Educational Resources Information Center

Hatchett, Melvin S.

This revised manual in basic merchandise display for trainees in distributive education, together with a separate answer key, contains 23 self-study assignments, each with training objectives, questions to answer, and student projects. Developed by a distributive education coordinator, these assignments cover a wide range of topics, from the…

Unraveling metamaterial properties in zigzag-base folded sheets.

PubMed

Eidini, Maryam; Paulino, Glaucio H

2015-09-01

Creating complex spatial objects from a flat sheet of material using origami folding techniques has attracted attention in science and engineering. In the present work, we use the geometric properties of partially folded zigzag strips to better describe the kinematics of known zigzag/herringbone-base folded sheet metamaterials such as Miura-ori. Inspired by the kinematics of a one-degree of freedom zigzag strip, we introduce a class of cellular folded mechanical metamaterials comprising different scales of zigzag strips. This class of patterns combines origami folding techniques with kirigami. Using analytical and numerical models, we study the key mechanical properties of the folded materials. We show that our class of patterns, by expanding on the design space of Miura-ori, is appropriate for a wide range of applications from mechanical metamaterials to deployable structures at small and large scales. We further show that, depending on the geometry, these materials exhibit either negative or positive in-plane Poisson's ratios. By introducing a class of zigzag-base materials in the current study, we unify the concept of in-plane Poisson's ratio for similar materials in the literature and extend it to the class of zigzag-base folded sheet materials.

Preliminary characterization of a laser-generated plasma sheet

DOE PAGES

Keiter, P. A.; Malamud, G.; Trantham, M.; ...

2014-12-10

We present the results from recent experiments to create a flowing plasma sheet. Two groups of three laser beams with nominally 1.5 kJ of energy per group were focused to separate pointing locations, driving a shock into a wedge target. As the shock breaks out of the wedge, the plasma is focused on center, creating a sheet of plasma. Measurements at 60 ns indicate the plasma sheet has propagated 2825 microns with an average velocity of 49 microns/ns. These experiments follow previous experiments, which are aimed at studying similar physics as that found in the hot spot region of cataclysmicmore » variables. Krauland et al created a flowing plasma, which represents the flowing plasma from the secondary star. This flow interacted with a stationary object, which represented the disk around the white dwarf. A reverse shock is a shock formed when a freely expanding plasma encounters an obstacle. Reverse shocks can be generated by a blast wave propagating through a medium. As a result, they can also be found in binary star systems where the flowing gas from a companion star interacts with the accretion disk of the primary star.« less

Light sheet theta microscopy for rapid high-resolution imaging of large biological samples.

PubMed

Migliori, Bianca; Datta, Malika S; Dupre, Christophe; Apak, Mehmet C; Asano, Shoh; Gao, Ruixuan; Boyden, Edward S; Hermanson, Ola; Yuste, Rafael; Tomer, Raju

2018-05-29

Advances in tissue clearing and molecular labeling methods are enabling unprecedented optical access to large intact biological systems. These developments fuel the need for high-speed microscopy approaches to image large samples quantitatively and at high resolution. While light sheet microscopy (LSM), with its high planar imaging speed and low photo-bleaching, can be effective, scaling up to larger imaging volumes has been hindered by the use of orthogonal light sheet illumination. To address this fundamental limitation, we have developed light sheet theta microscopy (LSTM), which uniformly illuminates samples from the same side as the detection objective, thereby eliminating limits on lateral dimensions without sacrificing the imaging resolution, depth, and speed. We present a detailed characterization of LSTM, and demonstrate its complementary advantages over LSM for rapid high-resolution quantitative imaging of large intact samples with high uniform quality. The reported LSTM approach is a significant step for the rapid high-resolution quantitative mapping of the structure and function of very large biological systems, such as a clarified thick coronal slab of human brain and uniformly expanded tissues, and also for rapid volumetric calcium imaging of highly motile animals, such as Hydra, undergoing non-isomorphic body shape changes.

Optimal processor assignment for pipeline computations

NASA Technical Reports Server (NTRS)

Nicol, David M.; Simha, Rahul; Choudhury, Alok N.; Narahari, Bhagirath

1991-01-01

The availability of large scale multitasked parallel architectures introduces the following processor assignment problem for pipelined computations. Given a set of tasks and their precedence constraints, along with their experimentally determined individual responses times for different processor sizes, find an assignment of processor to tasks. Two objectives are of interest: minimal response given a throughput requirement, and maximal throughput given a response time requirement. These assignment problems differ considerably from the classical mapping problem in which several tasks share a processor; instead, it is assumed that a large number of processors are to be assigned to a relatively small number of tasks. Efficient assignment algorithms were developed for different classes of task structures. For a p processor system and a series parallel precedence graph with n constituent tasks, an O(np2) algorithm is provided that finds the optimal assignment for the response time optimization problem; it was found that the assignment optimizing the constrained throughput in O(np2log p) time. Special cases of linear, independent, and tree graphs are also considered.

Optical elements formed by compressed gases: Analysis and potential applications

NASA Technical Reports Server (NTRS)

Howes, W. L.

1986-01-01

Spherical, cylindrical, and conical shock waves are optically analogous to gas lenses. The geometrical optics of these shock configurations are analyzed as they pertain to flow visualization instruments, particularly the rainbow schlieren apparatus and single-pass interferometers. It is proposed that a lens or mirror formed by gas compressed between plastic sheets has potential as a fluid visualization test object; as the objective mirror in a very large space-based telescope, communication antenna, or energy collector; as the objective mirror in inexpensive commercial telescopes; and as a component in fluid visualization apparatuses.

Fuel Cells for Backup Power in Telecommunications Facilities (Fact Sheet)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

2009-04-01

Telecommunications providers rely on backup power to maintain a constant power supply, to prevent power outages, and to ensure the operability of cell towers, equipment, and networks. The backup power supply that best meets these objectives is fuel cell technology.

South Carolina Guide for Selling.

ERIC Educational Resources Information Center

Elliott, Ronald T.

This curriculum guide provides materials for a secondary course in salesmanship. It contains 6 units that cover 33 competencies. Each competency is presented in a standard format: performance objective, resources, teaching activities, evaluation, and supplementary materials, including an information sheet, exercises, and checklists. Units and…

New evidence of the nonglaciated development of the northern part of the Western Siberian lowland in the Quaternary period

NASA Astrophysics Data System (ADS)

Sheinkman, V. S.; Melnikov, V. P.; Sedov, S. N.; Parnachev, V. P.

2017-12-01

To solve the controversially debated problem related to the areal extent of the ice sheet in Western Siberia in the Quaternary period, we have studied the development of cold born objects of this area estimating the relationships between them in terms of cryogenic diversity. We have obtained a field of new cross data related to the development of cryogenic and glacial phenomena, their relationship, and traces they left. The research showed that, in this area, the trend of rock freezing is clearly reflected in the Quaternary formations, but there were no conditions for ice sheet development even during the cryochrons.

Structure of deformed silicon and implications for low cost solar cells

NASA Technical Reports Server (NTRS)

Mardesich, N.; Leipold, M. H.; Turner, G. B.; Digges, T. G., Jr.

1978-01-01

The microstructure and minority carrier lifetime of silicon were investigated in uniaxially compressed silicon samples. The objective of the investigation was to determine if it is feasible to produce silicon solar cells from sheet formed by high temperature rolling. The initial structure of the silicon samples ranged from single crystal to fine-grained polycrystals. The samples had been deformed at strain rates of 0.1 to 8.5/sec and temperatures of 1270-1380 C with subsequent annealing at 1270-1380 C. The results suggest that high temperature rolling of silicon to produce sheet for cells of high efficiency is not practical.

Grouping puts figure-ground assignment in context by constraining propagation of edge assignment.

PubMed

Brooks, Joseph L; Brook, Joseph L; Driver, Jon

2010-05-01

Figure-ground organization involves the assignment of edges to a figural shape on one or the other side of each dividing edge. Established visual cues for edge assignment primarily concern relatively local rather than contextual factors. In the present article, we show that an assignment for a locally unbiased edge can be affected by an assignment of a remote contextual edge that has its own locally biased assignment. We find that such propagation of edge assignment from the biased remote context occurs only when the biased and unbiased edges are grouped. This new principle, whereby grouping constrains the propagation of figural edge assignment, emerges from both subjective reports and an objective short-term edge-matching task. It generalizes from moving displays involving grouping by common fate and collinearity, to static displays with grouping by similarity of edge-contrast polarity, or apparent occlusion. Our results identify a new contextual influence on edge assignment. They also identify a new mechanistic relation between grouping and figure-ground processes, whereby grouping between remote elements can constrain the propagation of edge assignment between those elements. Supplemental materials for this article may be downloaded from http://app.psychonomic-journals.org/content/supplemental.

A Multiple Ant Colony Metahuristic for the Air Refueling Tanker Assignment Problem

DTIC Science & Technology

2002-03-01

Problem The tanker assignment problem can be modeled as a job shop scheduling problem ( JSSP ). The JSSP is made up of n jobs, composed of m ordered...points) to be processed on all the machines (tankers). The problem with using JSSP is that the tanker assignment problem has multiple objectives... JSSP will minimize the time it takes for all jobs, but this may take an inordinate number of tankers. Thus using JSSP alone is not necessarily a good

Searching objective criteria for patient assignment in addiction treatment.

PubMed

López-Goñi, José J; Fernández-Montalvo, Javier; Arteaga, Alfonso; Esarte, Sonia

2017-05-01

The main aim of this study was to objectify the treatment assignment criteria used in a clinical centre for addiction treatment in Spain. A sample of 162 patients (87 inpatients and 75 outpatients) who sought treatment between 2010 and 2012 was assessed. Clinical characteristics (addiction severity, psychopathological symptoms, impulsiveness and maladjustment) of the two treatment groups (inpatient and outpatient) into which patients were assigned according to the clinical criteria of therapists were analysed to identify which variables were more relevant for patient placement. Moreover, the therapeutic progression of patients who met and did not meet the assignment criteria received was studied. According to the results, a score above 4 in the family/social support area of the European Addiction Severity Index (EuropASI), or, in cases of a score between 2 and 4 in the family/social area of EuropASI, a score above 2 in the partner subscale of the Maladjustment Scale correctly classified 73.5% of cases (96.6% of inpatients and 46.7% of outpatients). Comparisons of therapeutic results depending on matching or mismatching these assignment criteria showed a larger effect size in mismatching patient assignment criteria for outpatient treatment. The results obtained in this study provide an objective criterion for addicted patient placement. Moreover, from a cost-effective perspective, they question the necessity of inpatient treatment in most cases, demonstrating that outpatient treatment is a sufficient level of care. This study addresses the approach to assigning patients to the treatment modality that best fits them, implementing the least expensive level of care needed to achieve treatment success. Copyright © 2017 Elsevier Inc. All rights reserved.

Hazard Analysis for Building 34 Vacuum Glove Box Assembly

NASA Technical Reports Server (NTRS)

Meginnis, Ian

2014-01-01

One of the characteristics of an effective safety program is the recognition and control of hazards before mishaps or failures occur. Conducting potentially hazardous tests necessitates a thorough hazard analysis in order to prevent injury to personnel, and to prevent damage to facilities and equipment. The primary purpose of this hazard analysis is to define and address the potential hazards and controls associated with the Building 34 Vacuum Glove Box Assembly, and to provide the applicable team of personnel with the documented results. It is imperative that each member of the team be familiar with the hazards and controls associated with his/her particular tasks, assignments and activities while interfacing with facility test systems, equipment and hardware. In fulfillment of the stated purposes, the goal of this hazard analysis is to identify all hazards that have the potential to harm personnel, damage the facility or its test systems or equipment, test articles, Government or personal property, or the environment. This analysis may also assess the significance and risk, when applicable, of lost test objectives when substantial monetary value is involved. The hazards, causes, controls, verifications, and risk assessment codes have been documented on the hazard analysis work sheets in Appendix A of this document. The preparation and development of this report is in accordance with JPR 1700.1, "JSC Safety and Health Handbook" and JSC 17773 Rev D "Instructions for Preparation of Hazard Analysis for JSC Ground Operations".

Variability in Clinical Integration Achieved by Athletic Training Students across Different Clinical Sport Assignments

ERIC Educational Resources Information Center

Dodge, Thomas M.; Mazerolle, Stephanie M.; Bowman, Thomas G.

2015-01-01

Context: Clinical integration impacts athletic training students' (ATSs) motivation and persistence. Research has yet to elucidate the manner in which different clinical placements can influence clinical integration. Objective: To examine differences in the levels of clinical integration achieved by ATSs across various clinical sport assignments.…

Guidelines for assigning allowable properties to visually graded foreign species based on test data from full sized specimens

Treesearch

David W. Green; Bradley E. Shelley

2006-01-01

The objective of this document is to provide philosophy and guidelines for the assignment of allowable properties to visually graded dimension lumber produced from trees not grown in the United States. This document assumes, as a starting point, the procedures of ASTM D 1990.

Using a Wiki to Collaborate on a Study Guide

ERIC Educational Resources Information Center

Lending, Diane

2010-01-01

This paper introduces an end-of-semester assignment to create a study guide for the final exam. This assignment helps with two objectives of an introductory Management Information Systems course: collaboration and using Web 2.0 technologies. We argue that to truly understand collaboration, students must learn more than what collaboration is, they…

Entre Dos Mundos/Between Two Worlds: Youth Violence Prevention for Acculturating Latino Families

ERIC Educational Resources Information Center

Smokowski, Paul R.; Bacallao, Martica

2009-01-01

Objective: This study evaluated the efficacy of Entre Dos Mundos/Between Two Worlds (EDM) prevention for Latino adolescents. Method: In an experimental trial to compare implementation formats, 41 Latino families were randomly assigned to EDM action-oriented skills training groups, and 47 families were randomly assigned to unstructured EDM support…

Computer Assisted Assignment of Students to Schools to Achieve Desegregation.

ERIC Educational Resources Information Center

Illinois Inst. of Tech., Chicago. Research Inst.

To help school districts with the task of assigning students to schools in order to achieve desegregation, the Illinois Institute of Technology has developed a system involving the use of planning techniques and computer technology that greatly simplifies the school district's job. The key features of the system are objectivity, minimum…

UAB UTC domain 2 : development of a dynamic traffic assignment and simulation model for incident and emergency management applications in the Birmingham Region (Aim 1).

DOT National Transportation Integrated Search

2010-12-01

A number of initiatives were undertaken to support education, training, and technology transfer objectives related to UAB UTC Domain 2 Project: Development of a Dynamic Traffic Assignment and Simulation Model for Incident and Emergency Management App...

Teaching Technoliteracy: Assignments Requiring Microcomputer Applications in Oral Communication Courses.

ERIC Educational Resources Information Center

Reppert, James E.

This paper outlines methods for students in an introductory speech course at Southern Arkansas University to use microcomputers as essential research tools in class assignments. The outline is divided into seven projects, each with two objectives and a list of activities and procedures: (1) speech of introduction; (2) impromptu speech; (3)…

Cue Conflicts in Context: Interplay between Morphosyntax and Discourse Context in Danish Preschoolers' Semantic Role Assignment

ERIC Educational Resources Information Center

Thomsen, Ditte Boeg; Poulsen, Mads

2015-01-01

When learning their first language, children develop strategies for assigning semantic roles to sentence structures, depending on morphosyntactic cues such as case and word order. Traditionally, comprehension experiments have presented transitive clauses in isolation, and cross-linguistically children have been found to misinterpret object-first…

Fact Sheet: EPCRA Guidance on Reporting Options for Sections 311 and 312 and Some Interpretations

EPA Pesticide Factsheets

The objective is to streamline the reporting requirements for facilities under sections 311 and 312 of the Emergency Planning and Community Right-to-Know Act, and provide state and local agencies with flexibility in implementing these sections.

Introductory Industrial Technology I. Laboratory Activities.

ERIC Educational Resources Information Center

Towler, Alan L.; And Others

This guide contains 36 learning modules intended for use by technology teachers and students in grades 7 and 8. Each module includes a student laboratory activity and instructor's resource sheet. Each student activity includes the following: activity topic and overview, challenge statement, objectives, vocabulary/concepts reinforced,…

Aircraft Environmental Systems Mechanic. Part 2.

ERIC Educational Resources Information Center

Chanute AFB Technical Training Center, IL.

This packet contains learning modules designed for a self-paced course in aircraft environmental systems mechanics that was developed for the Air Force. Learning modules consist of some or all of the following materials: objectives, instructions, equipment, procedures, information sheets, handouts, workbooks, self-tests with answers, review…

Introductory Industrial Technology II. Laboratory Activities.

ERIC Educational Resources Information Center

Towler, Alan L.

This guide contains 29 learning modules intended for use by technology teachers and students in grade 8. Each module includes a student laboratory activity and instructor's resource sheet. Each student activity includes the following: activity topic and overview, challenge statement, objectives, vocabulary/concepts reinforced, equipment/supplies,…

Multi-objective optimization of hole characteristics during pulsed Nd:YAG laser microdrilling of gamma-titanium aluminide alloy sheet

NASA Astrophysics Data System (ADS)

Biswas, R.; Kuar, A. S.; Mitra, S.

2014-09-01

Nd:YAG laser microdrilled holes on gamma-titanium aluminide, a newly developed alloy having wide applications in turbine blades, engine valves, cases, metal cutting tools, missile components, nuclear fuel and biomedical engineering, are important from the dimensional accuracy and quality of hole point of view. Keeping this in mind, a central composite design (CCD) based on response surface methodology (RSM) is employed for multi-objective optimization of pulsed Nd:YAG laser microdrilling operation on gamma-titanium aluminide alloy sheet to achieve optimum hole characteristics within existing resources. The three characteristics such as hole diameter at entry, hole diameter at exit and hole taper have been considered for simultaneous optimization. The individual optimization of all three responses has also been carried out. The input parameters considered are lamp current, pulse frequency, assist air pressure and thickness of the job. The responses at predicted optimum parameter level are in good agreement with the results of confirmation experiments conducted for verification tests.

A submerged singularity method for calculating potential flow velocities at arbitrary near-field points

NASA Technical Reports Server (NTRS)

Maskew, B.

1976-01-01

A discrete singularity method has been developed for calculating the potential flow around two-dimensional airfoils. The objective was to calculate velocities at any arbitrary point in the flow field, including points that approach the airfoil surface. That objective was achieved and is demonstrated here on a Joukowski airfoil. The method used combined vortices and sources ''submerged'' a small distance below the airfoil surface and incorporated a near-field subvortex technique developed earlier. When a velocity calculation point approached the airfoil surface, the number of discrete singularities effectively increased (but only locally) to keep the point just outside the error region of the submerged singularity discretization. The method could be extended to three dimensions, and should improve nonlinear methods, which calculate interference effects between multiple wings, and which include the effects of force-free trailing vortex sheets. The capability demonstrated here would extend the scope of such calculations to allow the close approach of wings and vortex sheets (or vortices).

Contextual effects on perceived contrast: figure-ground assignment and orientation contrast.

PubMed

Self, Matthew W; Mookhoek, Aart; Tjalma, Nienke; Roelfsema, Pieter R

2015-02-02

Figure-ground segregation is an important step in the path leading to object recognition. The visual system segregates objects ('figures') in the visual scene from their backgrounds ('ground'). Electrophysiological studies in awake-behaving monkeys have demonstrated that neurons in early visual areas increase their firing rate when responding to a figure compared to responding to the background. We hypothesized that similar changes in neural firing would take place in early visual areas of the human visual system, leading to changes in the perception of low-level visual features. In this study, we investigated whether contrast perception is affected by figure-ground assignment using stimuli similar to those in the electrophysiological studies in monkeys. We measured contrast discrimination thresholds and perceived contrast for Gabor probes placed on figures or the background and found that the perceived contrast of the probe was increased when it was placed on a figure. Furthermore, we tested how this effect compared with the well-known effect of orientation contrast on perceived contrast. We found that figure-ground assignment and orientation contrast produced changes in perceived contrast of a similar magnitude, and that they interacted. Our results demonstrate that figure-ground assignment influences perceived contrast, consistent with an effect of figure-ground assignment on activity in early visual areas of the human visual system. © 2015 ARVO.

Silk: Optical Properties over 12.6 Octaves THz-IR-Visible-UV Range

PubMed Central

Balčytis, Armandas; Ryu, Meguya; Wang, Xuewen; Novelli, Fabio; Seniutinas, Gediminas; Du, Shan; Wang, Xungai; Li, Jingliang; Davis, Jeffrey; Appadoo, Dominique; Morikawa, Junko; Juodkazis, Saulius

2017-01-01

Domestic (Bombyx mori) and wild (Antheraea pernyi) silk fibers were characterised over a wide spectral range from THz 8 cm−1 (λ= 1.25 mm, f= 0.24 THz) to deep-UV 50×103 cm−1 (λ= 200 nm, f= 1500 THz) wavelengths or over a 12.6 octave frequency range. Spectral features at β-sheet, α-coil and amorphous fibroin were analysed at different spectral ranges. Single fiber cross sections at mid-IR were used to determine spatial distribution of different silk constituents and revealed an α-coil rich core and more broadly spread β-sheets in natural silk fibers obtained from wild Antheraea pernyi moths. Low energy T-ray bands at 243 and 229 cm−1 were observed in crystalline fibers of domestic and wild silk fibers, respectively, and showed no spectral shift down to 78 K temperature. A distinct 20±4 cm−1 band was observed in the crystalline Antheraea pernyi silk fibers. Systematic analysis and assignment of the observed spectral bands is presented. Water solubility and biodegradability of silk, required for bio-medical and sensor applications, are directly inferred from specific spectral bands. PMID:28772716

HEALTHY study school food service revenue and expense report.

PubMed

Treviño, Roberto P; Pham, Trang; Mobley, Connie; Hartstein, Jill; El Ghormli, Laure; Songer, Thomas

2012-09-01

Food service directors have a concern that federal reimbursement is not meeting the demands of increasing costs of healthier meals. The purpose of this article is to report the food option changes and the annual revenues and expenses of the school food service environment. The HEALTHY study was a 3-year (2006 to 2009) randomized, cluster-designed trial conducted in 42 middle schools at 7 field centers. The schools selected had at least 50% of students who were eligible for free or reduced-price lunch or who belonged to a minority group. A randomly assigned half of the HEALTHY schools received a school health intervention program consisting of 4 integrated components: nutrition, physical activity, behavioral knowledge and skills, and social marketing. The nutrition component consisted of changing the meal plans to meet 5 nutrition goals. Revenue and expense data were collected from income statements, federal meal records, à la carte sale sheets, school store sale sheets, donated money/food records, and vending machines. Although more intervention schools reached the nutritional goals than control schools, revenues and expenses were not significantly different between groups. The HEALTHY study showed no adverse effect of school food policies on food service finances. © 2012, American School Health Association.

HEALTHY Study School Food Service Revenue and Expense Report

PubMed Central

Treviño, Roberto P.; Pham, Trang; Mobley, Connie; Hartstein, Jill; El ghormli, Laure; Songer, Thomas

2013-01-01

BACKGROUND Food service directors have a concern that federal reimbursement is not meeting the demands of increasing costs of healthier meals. The purpose of this article is to report the food option changes and the annual revenues and expenses of the school food service environment. METHODS The HEALTHY study was a 3-year (2006 to 2009) randomized, cluster-designed trial conducted in 42 middle schools at 7 field centers. The schools selected had at least 50% of students who were eligible for free or reduced-price lunch or who belonged to a minority group. A randomly assigned half of the HEALTHY schools received a school health intervention program consisting of 4 integrated components: nutrition, physical activity, behavioral knowledge and skills, and social marketing. The nutrition component consisted of changing the meal plans to meet 5 nutrition goals. Revenue and expense data were collected from income statements, federal meal records, à la carte sale sheets, school store sale sheets, donated money/food records, and vending machines. RESULTS Although more intervention schools reached the nutritional goals than control schools, revenues and expenses were not significantly different between groups. CONCLUSION The HEALTHY study showed no adverse effect of school food policies on food service finances. PMID:22882105

Constraining Future Sea Level Rise Estimates from the Amundsen Sea Embayment, West Antarctica

NASA Astrophysics Data System (ADS)

Nias, I.; Cornford, S. L.; Edwards, T.; Gourmelen, N.; Payne, A. J.

2016-12-01

The Amundsen Sea Embayment (ASE) is the primary source of mass loss from the West Antarctic Ice Sheet. The catchment is particularly susceptible to grounding line retreat, because the ice sheet is grounded on bedrock that is below sea level and deepening towards its interior. Mass loss from the ASE ice streams, which include Pine Island, Thwaites and Smith glaciers, is a major uncertainty on future sea level rise, and understanding the dynamics of these ice streams is essential to constraining this uncertainty. The aim of this study is to construct a distribution of future ASE sea level contributions from an ensemble of ice sheet model simulations and observations of surface elevation change. A 284 member ensemble was performed using BISICLES, a vertically-integrated ice flow model with adaptive mesh refinement. Within the ensemble parameters associated with basal traction, ice rheology and sub-shelf melt rate were perturbed, and the effect of bed topography and sliding law were also investigated. Initially each configuration was run to 50 model years. Satellite observations of surface height change were then used within a Bayesian framework to assign likelihoods to each ensemble member. Simulations that better reproduced the current thinning patterns across the catchment were given a higher score. The resulting posterior distribution of sea level contributions is narrower than the prior distribution, although the central estimates of sea level rise are similar between the prior and posterior. The most extreme simulations were eliminated and the remaining ensemble members were extended to 200 years, using a simple melt rate forcing.

Contact Prediction for Beta and Alpha-Beta Proteins Using Integer Linear Optimization and its Impact on the First Principles 3D Structure Prediction Method ASTRO-FOLD

PubMed Central

Rajgaria, R.; Wei, Y.; Floudas, C. A.

2010-01-01

An integer linear optimization model is presented to predict residue contacts in β, α + β, and α/β proteins. The total energy of a protein is expressed as sum of a Cα – Cα distance dependent contact energy contribution and a hydrophobic contribution. The model selects contacts that assign lowest energy to the protein structure while satisfying a set of constraints that are included to enforce certain physically observed topological information. A new method based on hydrophobicity is proposed to find the β-sheet alignments. These β-sheet alignments are used as constraints for contacts between residues of β-sheets. This model was tested on three independent protein test sets and CASP8 test proteins consisting of β, α + β, α/β proteins and was found to perform very well. The average accuracy of the predictions (separated by at least six residues) was approximately 61%. The average true positive and false positive distances were also calculated for each of the test sets and they are 7.58 Å and 15.88 Å, respectively. Residue contact prediction can be directly used to facilitate the protein tertiary structure prediction. This proposed residue contact prediction model is incorporated into the first principles protein tertiary structure prediction approach, ASTRO-FOLD. The effectiveness of the contact prediction model was further demonstrated by the improvement in the quality of the protein structure ensemble generated using the predicted residue contacts for a test set of 10 proteins. PMID:20225257

Determining Greenland Ice Sheet Accumulation Rates from Radar Remote Sensing

NASA Technical Reports Server (NTRS)

Jezek, Kenneth C.

2002-01-01

An important component of NASA's Program for Arctic Regional Climate Assessment (PARCA) is a mass balance investigation of the Greenland Ice Sheet. The mass balance is calculated by taking the difference between the areally Integrated snow accumulation and the net ice discharge of the ice sheet. Uncertainties in this calculation Include the snow accumulation rate, which has traditionally been determined by interpolating data from ice core samples taken from isolated spots across the ice sheet. The sparse data associated with ice cores juxtaposed against the high spatial and temporal resolution provided by remote sensing , has motivated scientists to investigate relationships between accumulation rate and microwave observations as an option for obtaining spatially contiguous estimates. The objective of this PARCA continuation proposal was to complete an estimate of surface accumulation rate on the Greenland Ice Sheet derived from C-band radar backscatter data compiled in the ERS-1 SAR mosaic of data acquired during, September-November, 1992. An empirical equation, based on elevation and latitude, is used to determine the mean annual temperature. We examine the influence of accumulation rate, and mean annual temperature on C-band radar backscatter using a forward model, which incorporates snow metamorphosis and radar backscatter components. Our model is run over a range of accumulation and temperature conditions. Based on the model results, we generate a look-up table, which uniquely maps the measured radar backscatter, and mean annual temperature to accumulation rate. Our results compare favorably with in situ accumulation rate measurements falling within our study area.

Unusual radar echoes from the Greenland ice sheet

NASA Technical Reports Server (NTRS)

Rignot, E. J.; Vanzyl, J. J.; Ostro, S. J.; Jezek, K. C.

1993-01-01

In June 1991, the NASA/Jet Propulsion Laboratory airborne synthetic-aperture radar (AIRSAR) instrument collected the first calibrated data set of multifrequency, polarimetric, radar observations of the Greenland ice sheet. At the time of the AIRSAR overflight, ground teams recorded the snow and firn (old snow) stratigraphy, grain size, density, and temperature at ice camps in three of the four snow zones identified by glaciologists to characterize four different degrees of summer melting of the Greenland ice sheet. The four snow zones are: (1) the dry-snow zone, at high elevation, where melting rarely occurs; (2) the percolation zone, where summer melting generates water that percolates down through the cold, porous, dry snow and then refreezes in place to form massive layers and pipes of solid ice; (3) the soaked-snow zone where melting saturates the snow with liquid water and forms standing lakes; and (4) the ablation zone, at the lowest elevations, where melting is vigorous enough to remove the seasonal snow cover and ablate the glacier ice. There is interest in mapping the spatial extent and temporal variability of these different snow zones repeatedly by using remote sensing techniques. The objectives of the 1991 experiment were to study changes in radar scattering properties across the different melting zones of the Greenland ice sheet, and relate the radar properties of the ice sheet to the snow and firn physical properties via relevant scattering mechanisms. Here, we present an analysis of the unusual radar echoes measured from the percolation zone.

Apparatus for and method of simulating turbulence

DOEpatents

Dimas, Athanassios; Lottati, Isaac; Bernard, Peter; Collins, James; Geiger, James C.

2003-01-01

In accordance with a preferred embodiment of the invention, a novel apparatus for and method of simulating physical processes such as fluid flow is provided. Fluid flow near a boundary or wall of an object is represented by a collection of vortex sheet layers. The layers are composed of a grid or mesh of one or more geometrically shaped space filling elements. In the preferred embodiment, the space filling elements take on a triangular shape. An Eulerian approach is employed for the vortex sheets, where a finite-volume scheme is used on the prismatic grid formed by the vortex sheet layers. A Lagrangian approach is employed for the vortical elements (e.g., vortex tubes or filaments) found in the remainder of the flow domain. To reduce the computational time, a hairpin removal scheme is employed to reduce the number of vortex filaments, and a Fast Multipole Method (FMM), preferably implemented using parallel processing techniques, reduces the computation of the velocity field.

Cardiac Light-Sheet Fluorescent Microscopy for Multi-Scale and Rapid Imaging of Architecture and Function

NASA Astrophysics Data System (ADS)

Fei, Peng; Lee, Juhyun; Packard, René R. Sevag; Sereti, Konstantina-Ioanna; Xu, Hao; Ma, Jianguo; Ding, Yichen; Kang, Hanul; Chen, Harrison; Sung, Kevin; Kulkarni, Rajan; Ardehali, Reza; Kuo, C.-C. Jay; Xu, Xiaolei; Ho, Chih-Ming; Hsiai, Tzung K.

2016-03-01

Light Sheet Fluorescence Microscopy (LSFM) enables multi-dimensional and multi-scale imaging via illuminating specimens with a separate thin sheet of laser. It allows rapid plane illumination for reduced photo-damage and superior axial resolution and contrast. We hereby demonstrate cardiac LSFM (c-LSFM) imaging to assess the functional architecture of zebrafish embryos with a retrospective cardiac synchronization algorithm for four-dimensional reconstruction (3-D space + time). By combining our approach with tissue clearing techniques, we reveal the entire cardiac structures and hypertrabeculation of adult zebrafish hearts in response to doxorubicin treatment. By integrating the resolution enhancement technique with c-LSFM to increase the resolving power under a large field-of-view, we demonstrate the use of low power objective to resolve the entire architecture of large-scale neonatal mouse hearts, revealing the helical orientation of individual myocardial fibers. Therefore, our c-LSFM imaging approach provides multi-scale visualization of architecture and function to drive cardiovascular research with translational implication in congenital heart diseases.

Some recent developments in sheet metal forming for production of lightweight automotive parts

NASA Astrophysics Data System (ADS)

Tisza, M.; Lukács, Zs; Kovács, P.; Budai, D.

2017-09-01

Low cost manufacturing in the automotive industry is one of the main targets due to the ever increasing global competition among car manufacturers all over the World. Sheet metal forming is one of the most important key technologies in the automotive industry; therefore the elaboration of new, innovative low cost manufacturing processes is one of the main objectives in sheet metal forming as well. In 2015 with the initiative of the Imperial College London a research consortium was established under the umbrella Low Cost Materials Processing Technologies for Mass Production of Lightweight Vehicles. The primary aim of this project is to provide affordable low cost weight reduction in mass production of vehicles considering the entire life-cycle. In this project, 19 European Institutions (Universities and Research Institutions) from 9 European countries are participating with the above targets. The University of Miskolc is one of the members of this research Consortium. In this paper, some preliminary results with the contributions of the University of Miskolc will be introduced.

Evaluation of the ion implantation process for production of solar cells from silicon sheet materials

NASA Technical Reports Server (NTRS)

Spitzer, M. B.

1983-01-01

The objective of this program is the investigation and evaluation of the capabilities of the ion implantation process for the production of photovoltaic cells from a variety of present-day, state-of-the-art, low-cost silicon sheet materials. Task 1 of the program concerns application of ion implantation and furnace annealing to fabrication of cells made from dendritic web silicon. Task 2 comprises the application of ion implantation and pulsed electron beam annealing (PEBA) to cells made from SEMIX, SILSO, heat-exchanger-method (HEM), edge-defined film-fed growth (EFG) and Czochralski (CZ) silicon. The goals of Task 1 comprise an investigation of implantation and anneal processes applied to dendritic web. A further goal is the evaluation of surface passivation and back surface reflector formation. In this way, processes yielding the very highest efficiency can be evaluated. Task 2 seeks to evaluate the use of PEBA for various sheet materials. A comparison of PEBA to thermal annealing will be made for a variety of ion implantation processes.

The Interactive Effects of the Availability of Objectives and/or Rules on Computer-Based Learning: A Replication.

ERIC Educational Resources Information Center

Merrill, Paul F.; And Others

To replicate and extend the results of a previous study, this project investigated the effects of behavioral objectives and/or rules on computer-based learning task performance. The 133 subjects were randomly assigned to an example-only, objective-example, rule example, or objective-rule example group. The availability of rules and/or objectives…

Asteroid selection for mission opportunities. Appendix: Asteroid data sheets

NASA Technical Reports Server (NTRS)

1972-01-01

The characteristics of asteroids selected as possible space mission objectives are presented. The asteroids are described according to: (1) magnitude, (2) spectral reflectivity; (3) phase factors, (4) polarization, (5) light curve, and (6) physical parameters. The data are tabulated on specific formats for each asteroid considered.

Housing and Home Furnishings Modules.

ERIC Educational Resources Information Center

Clemson Univ., SC. Vocational Education Media Center.

These sixty-seven modules provide student materials for a home economics course in housing and home furnishings. (A companion instructor's guide is available separately--see note.) Each module contains an objective, student information, learning activities (and activity sheets as needed), student self-checks, student self-check answers, check-out…

Aircraft Environmental Systems Mechanic. Part 1.

ERIC Educational Resources Information Center

Chanute AFB Technical Training Center, IL.

This packet contains learning modules for a self-paced course in aircraft environmental systems mechanics that was developed for the Air Force. Each learning module consists of some or all of the following: objectives, instructions, equipment, procedures, information sheets, handouts, self-tests with answers, review section, tests, and response…

Practical Nursing. Volume II. Health Occupations Education. Revised.

ERIC Educational Resources Information Center

Rogers, Helen V.; Reid-Sloan, Jamee

This curriculum guide, revised from a 1975 edition, provides teachers with up-to-date information and skill-related applications needed by practical nurses. It includes 4 sections and 24 instructional units. Each unit of instruction consists of eight basic components: performance objectives, teacher activities, information sheets, assignment…

Microelectronics and Special Education. CET/MEP Information Sheet.

ERIC Educational Resources Information Center

Council for Educational Technology, London (England).

Used as an additional aid by the teacher, microelectronics can assist mentally and physically handicapped children to meet educational objectives that have been specifically agreed upon for the individual child. Microelectronics can help deaf children develop speech production, communication skills, and grammar and sentence construction;…

Basics of Desktop Publishing. Teacher Edition.

ERIC Educational Resources Information Center

Beeby, Ellen

This color-coded teacher's guide contains curriculum materials designed to give students an awareness of various desktop publishing techniques before they determine their computer hardware and software needs. The guide contains six units, each of which includes some or all of the following basic components: objective sheet, suggested activities…

Forestry. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum is designed to provide training in skills used by technicians and foresters throughout the world who plant, care for, and harvest trees. It contains 16 units. Each instructional unit includes some or all of the basic components of a unit of instruction: performance objectives, suggested activities, handouts, information sheets,…

Learn, Grow, Become. TSA Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This revised curriculum guide contains five units that are designed to help students develop an understanding of the mission of the Technology Student Association (TSA). Each unit follows a standard format that includes some or all of these basic components: performance objectives, suggested activities, handouts, information sheets, supplements,…

How Does XML Help Libraries?

ERIC Educational Resources Information Center

Banerjee, Kyle

2002-01-01

Discusses XML, how it has transformed the way information is managed and delivered, and its impact on libraries. Topics include how XML differs from other markup languages; the document object model (DOM); style sheets; practical applications for archival materials, interlibrary loans, digital collections, and MARC data; and future possibilities.…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fact sheet describing the National Renewable Energy Laboratory's (NREL's) Fuel Cell Technology Status Analysis Project. NREL is seeking fuel cell industry partners from the United States and abroad to participate in an objective and credible analysis of commercially available fuel cell products to benchmark the current state of the technology and support industry growth.

Aquaculture. Teacher Edition.

ERIC Educational Resources Information Center

Walker, Susan S.

This color-coded guide was developed to assist teachers in helping interested students plan, build, stock, and run aquaculture facilities of varied sizes. The guide contains 15 instructional units, each of which includes some or all of the following basic components: objective sheet, suggested activities for the teacher, instructor supplements,…

System Engineering of Aerospace and Advanced Technology Programs at AN Astronautics Company

NASA Astrophysics Data System (ADS)

Kennedy, Mike O.

The purpose of this Record of Study is to document an internship with the Martin Marietta Astronautics Group in Denver, Colorado that was performed in partial fulfillment of the requirements for the Doctor of Engineering degree at Texas A&M University, and to demonstrate that the internship objectives have been met. The internship included assignments with two Martin Marietta companies, on three different programs and in four areas of engineering. The Record of Study takes a first-hand look at system engineering, SDI and advanced program management, and the way Martin Marietta conducts business. The five internship objectives were related to assignments in system modeling, system integration, engineering analysis and technical management. In support of the first objective, the effects of thermally and mechanically induced mirror surface distortions upon the wavefront intensity field of a high energy laser beam passing through the optical train of a space-based laser system were modeled. To satisfy the second objective, the restrictive as opposed to the broad interpretation of the 1972 ABM Treaty, and the capability of the Strategic Defense Initiative Zenith Star Program to comply with the Treaty were evaluated. For the third objective, the capability of Martin Marietta to develop an automated analysis system to integrate and analyze Superconducting Super Collider detector designs was investigated. For the fourth objective, the thermal models that were developed in support of the Small Intercontinental Ballistic Missile flight tests were described. And in response to the fifth objective, the technical management role of the Product Integrity Engineer assigned to the Zenith Star spacecraft's Beam Control and Transfer Subsystem was discussed. This Record of Study explores the relationships between the engineering, business, security and social concerns associated with the practice of engineering and the management of programs by a major defense contractor.

Short-period oscillations in photoemission from thin films of Cr(100)

NASA Astrophysics Data System (ADS)

Vyalikh, Denis V.; Zahn, Peter; Richter, Manuel; Dedkov, Yu. S.; Molodtsov, S. L.

2005-07-01

Angle-resolved photoemission (PE) study of thin films of Cr grown on Fe(100) reveals thickness-dependent short-period oscillations of the PE intensity close to the Fermi energy at k‖˜0 . The oscillations are assigned to quantum-well states (QWS) caused by the nesting between the Fermi-surface sheets around the Γ and the X points in the Brillouin zone of antiferromagnetic Cr. The experimental data are confirmed by density-functional calculations applying a screened Korringa-Kohn-Rostoker Green’s function method. The period of the experimentally observed QWS oscillations amounts to about 2.6 monolayers and is larger than the fundamental 2-monolayer period of antiferromagnetic coupling in Cr.

The vibrational spectrum of the hydrated alanine-leucine peptide in the amide region from IR experiments and first principles calculations

NASA Astrophysics Data System (ADS)

Hassan, Irtaza; Donati, Luca; Stensitzki, Till; Keller, Bettina G.; Heyne, Karsten; Imhof, Petra

2018-04-01

We have combined infrared (IR) experiments with molecular dynamics (MD) simulations in solution at finite temperature to analyse the vibrational signature of the small floppy peptide Alanine-Leucine. IR spectra computed from first-principles MD simulations exhibit no distinct differences between conformational clusters of α -helix or β -sheet-like folds with different orientations of the bulky leucine side chain. All computed spectra show two prominent bands, in good agreement with the experiment, that are assigned to the stretch vibrations of the carbonyl and carboxyl group, respectively. Variations in band widths and exact maxima are likely due to small fluctuations in the backbone torsion angles.

Educational Strategies for Learning to Learn from Role Models.

ERIC Educational Resources Information Center

Williams, Martha

The way that socialization, via role modeling, can be enhanced in professional education is discussed, and 10 class assignments are used to illustrate teaching methods for enhancing role modeling, based on a course on women in administration at The University of Texas at Austin. Among the objectives of the course assignments are the following: to…

Multicultural Media Authorship: Using Technology to Create Children's Literature Texts

ERIC Educational Resources Information Center

Byker, Erik Jon; Good, Amy J.; Miller, Erin; Kissel, Brian

2018-01-01

The purpose of this article is to describe and report on how a group of teacher candidates used technology to create multicultural texts which integrated literacy and social studies. To meet this purpose, the authors briefly describe the objectives of the assignment, examine 41 teacher candidates' perceptions of the assignment, and discuss media…

The "Mentor Paper" Writing Assignment in One Community College Puente Class: Preliminary Report from a Participant Observer.

ERIC Educational Resources Information Center

Cazden, Courtney B.

An educator participating in a community college Puente class as both participant and observer analyzes the structure and experience of one writing assignment representative of the program's objectives. The Puente program combines teaching, counseling, and mentoring to California community college students as a means of promoting learning,…

"The Goal" Project: A Group Assignment to Encourage Creative Thinking, Leadership Abilities and Communication Skills

ERIC Educational Resources Information Center

Huff, Patricia Lee

2014-01-01

The classroom assignment described in this paper, "The Goal" Project, gives students an opportunity to develop four of the skills and abilities required to be a successful accountant. In 1990, the Accounting Education Change Commission issued Position Statement Number One, Objectives of Education for Accountants. Appendix B of that…

41 CFR 102-3.125 - How should agencies consider the roles of advisory committee members and staff?

Code of Federal Regulations, 2010 CFR

2010-07-01

... consider the roles of advisory committee members and staff? 102-3.125 Section 102-3.125 Public Contracts... How should agencies consider the roles of advisory committee members and staff? FACA does not assign... critical roles in achieving the goals and objectives assigned to advisory committees. Agency heads...

The Influence of Consistent Assignment on Nursing Home Deficiency Citations

ERIC Educational Resources Information Center

Castle, Nicholas G.

2011-01-01

Objective: The association of consistent assignment of nurse aides (NAs) with quality of care and quality of life of nursing home residents is examined (using 5 groups of deficiency citations). Methods: Data used came from a survey of nursing home administrators, the Online Survey Certification and Reporting data, and the Area Resource File. The…

TH-AB-209-04: 3D Light Sheet Luminescence Imaging with Cherenkov Radiation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bruza, P; Lin, H; Jarvis, L

Purpose: To recover a three-dimensional density distribution of luminescent molecular probes located several centimeters deep within a highly scattering tissue. Methods: We developed a novel sheet beam Cherenkov-excited luminescence scanned imaging (CELSI) methodology. The sample was irradiated by a horizontally oriented, vertically scanned 6 MV X-ray sheet beam (200mm × 5mm, 0.2mm vertical step) from a radiotherapy linear accelerator. The resulting Cherenkov light emission – and thus luminescent probe excitation – occurred exclusively along the irradiation plane due to a short diffusion path of secondary particles and Cherenkov photons. Cherenkov-excited luminescence was detected orthogonally to the sheet beam by gated,more » intensified charge coupled device camera. Analogously to light sheet microscopy, a series of luminescence images was taken for varied axial positions (depths) of the Cherenkov light sheet in sample. Knowledge of the excitation plane position allowed a 3D image stack deconvolution and depth-variant attenuation correction. The 3D image post-processing yielded a true spatial density distribution of luminescent molecules in highly scattering tissue. Results: We recovered a three-dimensional shape and position of 400 µL lesion-mimicking phantom tubes containing 25 µM solution of PtG4 molecular probe from 3 centimeter deep tissue-like media. The high sensitivity of CELSI also allowed resolving 100 micron capillaries of test solution. Functional information of partial oxygen pressure at the site of PtG4 molecular probe was recovered from luminescence lifetime CELSI. Finally, in-vivo sheet beam CELSI localized milimeter-sized PtG4-labelled tumor phantoms in multiple biological objects (hairless mice) from single scan. Conclusion: Presented sheet beam CELSI technique greatly extended the useful depth range of luminescence molecular imaging. More importantly, the light sheet microscopy approach was successfully adapted to CELSI, providing means to recover a completely attenuation-corrected 3D image of luminescent probe distribution. Gated CELSI acquisition yielded functional information of a spatially resolved oxygen concentration map of deep lying targets. This work was supported by NIH research grant R01CA109558 and R21EB017559, as well as by Pilot Grant Funds from the Norris Cotton Cancer Center.« less

Assessing Students' Structured Programming Skills with Java: The "Blue, Berry, and Blueberry" Assignment

ERIC Educational Resources Information Center

Zhang, Xihui

2010-01-01

Java is an object-oriented programming language. From a software engineering perspective, object-oriented design and programming is used at the architectural design, and structured design and programming is used at the detailed design within methods. As such, structured programming skills are fundamental to more advanced object-oriented…

Laser processing for strengthening of the self-restoring metal-elastomer interface on a silicone sheet

NASA Astrophysics Data System (ADS)

Yasuda, Kiyokazu

2012-08-01

A self-restoring microsystem is a unique concept which realizes the sensing functionality and robust interface which mechanically and electrically connects a deformable object such as a human body with printed electronic devices. For this purpose, the formation of conductive wiring on an elastomer substrate was attempted using the nickel ink printing process. Before the wiring process, surface patterning of a silicone sheet by a galvano-scanned infrared laser was conducted for the enhancement of interface adhesion of the metal deposit and polymer. Characterization of the fabricated pattern was conducted by optical microscopy. The novel method was successfully demonstrated as a fabrication of selective patterns of metal particles on self-restoring MEMS.

Local laser-strengthening: Customizing the forming behavior of car body steel sheets

NASA Astrophysics Data System (ADS)

Wagner, M.; Jahn, A.; Beyer, E.; Balzani, D.

2018-05-01

Future trends in designing lightweight components especially for automotive applications increasingly require complex and delicate structures with highest possible level of capacity [1]. The manufacturing of metallic car body components is primarily realized by deep or stretch drawing. The forming process of especially cold rolled and large-sized components is typically characterized by inhomogeneous stress and strain distributions. As a result, the avoidance of undesirable deep drawing effects like earing and local necking is among the greatest challenges in forming complex car body structures [2]. Hence, a novel local laser-treatment approach with the objective of customizing the forming behavior of car body steel sheets is currently explored.

van der Waals interactions between nanostructures: Some analytic results from series expansions

NASA Astrophysics Data System (ADS)

Stedman, T.; Drosdoff, D.; Woods, L. M.

2014-01-01

The van der Waals force between objects of nontrivial geometries is considered. A technique based on a perturbation series approach is formulated in the dilute limit. We show that the dielectric response and object size can be decoupled and dominant contributions in terms of object separations can be obtained. This is a powerful method, which enables straightforward calculations of the interaction for different geometries. Our results for planar structures, such as thin sheets, infinitely long ribbons, and ribbons with finite dimensions, may be applicable for nanostructured devices where the van der Waals interaction plays an important role.

Inter-annual Variations in Snow/Firn Density over the Greenland Ice Sheet by Combining GRACE gravimetry and Envisat Altimetry

NASA Astrophysics Data System (ADS)

Su, X.; Shum, C. K.; Guo, J.; Howat, I.; Jezek, K. C.; Luo, Z.; Zhou, Z.

2017-12-01

Satellite altimetry has been used to monitor elevation and volume change of polar ice sheets since the 1990s. In order to derive mass change from the measured volume change, different density assumptions are commonly used in the research community, which may cause discrepancies on accurately estimating ice sheets mass balance. In this study, we investigate the inter-annual anomalies of mass change from GRACE gravimetry and elevation change from Envisat altimetry during years 2003-2009, with the objective of determining inter-annual variations of snow/firn density over the Greenland ice sheet (GrIS). High positive correlations (0.6 or higher) between these two inter-annual anomalies at are found over 93% of the GrIS, which suggests that both techniques detect the same geophysical process at the inter-annual timescale. Interpreting the two anomalies in terms of near surface density variations, over 80% of the GrIS, the inter-annual variation in average density is between the densities of snow and pure ice. In particular, at the Summit of Central Greenland, we validate the satellite data estimated density with the in situ data available from 75 snow pits and 9 ice cores. This study provides constraints on the currently applied density assumptions for the GrIS.

Comprehensive computerized diabetes registry. Serving the Cree of Eeyou Istchee (eastern James Bay).

PubMed Central

Dannenbaum, D.; Verronneau, M.; Torrie, J.; Smeja, H.; Robinson, E.; Dumont, C.; Kovitch, I.; Webster, T.

1999-01-01

PROBLEM BEING ADDRESSED: Diabetes is rapidly evolving as a major health concern in the Cree population of eastern James Bay (Eeyou Istchee). The Cree Board of Health and Social Services of James Bay (CBHSSJB) diabetes registry was the initial phase in the development of a comprehensive program for diabetes in this region. OBJECTIVE OF PROGRAM: The CBHSSJB diabetes registry was developed to provide a framework to track the prevalence of diabetes and the progression of diabetic complications. The database will also identify patients not receiving appropriate clinical and laboratory screening for diabetic complications, and will provide standardized clinical flow sheets for routine patient management. MAIN COMPONENTS OF PROGRAM: The CBHSSJB diabetes registry uses a system of paper registration forms and clinical flow sheets kept in the nine community clinics. Information from these sheets is entered into a computer database annually. The flow sheets serve as a guideline for appropriate management of patients with diabetes, and provide a one-page summary of relevant clinical and laboratory information. CONCLUSIONS: A diabetes registry is vital to follow the progression of diabetes and diabetic complications in the region served by the CBHSSJB. The registry system incorporates both a means for regional epidemiologic monitoring of diabetes mellitus and clinical tools for managing patients with the disease. PMID:10065310

Entrepreneur Training Program. Getting Started.

ERIC Educational Resources Information Center

De Maria, Richard

This student workbook on starting a small business is part of the entrepreneur training program at Ocean County (New Jersey) Vocational-Technical Schools. The workbook consists of 16 units containing goals and objectives, study questions, exercises, sample materials, and information sheets. Unit topics are as follows: being a small business owner;…

A Beginner's Course in Tunisian Arabic.

ERIC Educational Resources Information Center

Amor, Taoufik Ben

This guide is designed for the Arabic language training of Peace Corps volunteers serving in Tunisia and focuses on daily communication skills needed in that context. It contains 15 lessons, each made up of: a teacher's guide sheet, which outlines specific objectives, contents, and materials needed; a dialogue introducing the lesson's theme; a…

Nutrition. Learning Activity Package.

ERIC Educational Resources Information Center

Lee, Carolyn

This learning activity package on nutrition is one of a series of 12 titles developed for use in health occupations education programs. Materials in the package include objectives, a list of materials needed, a list of definitions, information sheets, reviews (self evaluations) of portions of the content, and answers to reviews. These topics are…

Shock & Anaphylactic Shock. Learning Activity Package.

ERIC Educational Resources Information Center

Hime, Kirsten

This learning activity package on shock and anaphylactic shock is one of a series of 12 titles developed for use in health occupations education programs. Materials in the package include objectives, a list of materials needed, information sheets, reviews (self evaluations) of portions of the content, and answers to reviews. These topics are…

Introduction to Surgical Technology. Teacher Edition.

ERIC Educational Resources Information Center

Bushey, Vicki; And Others

This instructor's manual contains 14 units of instruction for a course on surgical technology designed to include the entry-level competencies students need to enter any of the more advanced surgical technology courses. Each unit includes some or all of the following basic components of a unit of instruction: objective sheet, suggested activities…

New Mexico State Secondary School Science-Based Nutrition Curriculum.

ERIC Educational Resources Information Center

Ecklund, Susan, Ed.; Smalley, Katherine, Ed.

This curriculum guide provides instructional materials for a 10-unit secondary-level science-based nutrition course. Each unit contains some or all of the following components: a summary sheet for each function, including generalizations with corresponding objectives, additional learning activities, and additional resources; unit outline; pretest;…

Humane Education: Resource Guide. A Guide for Elementary School Teachers.

ERIC Educational Resources Information Center

New York City Board of Education, Brooklyn, NY. Div. of Curriculum and Instruction.

Humane education promotes responsible behavior and improves the quality of life for animals and humans. Teaching the humane treatment of animals is a complex, philosophical, and values-oriented subject. Lessons for each grade level have performance objectives, materials, and activities. Student activity sheets are provided for follow-up…

Introduction to Natural Resources. Teacher Edition.

ERIC Educational Resources Information Center

Hehn, Darold; Newport, Bob

This color-coded teacher's guide contains curriculum materials designed to help students develop an awareness of renewable and nonrenewable natural resources and to identify occupations in the area of natural resources. The guide contains nine units, each of which includes some or all of the following basic components: objective sheet, suggested…

Soil, Plant, and Crop Science. Teacher Edition.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This package contains an instructor's manual, an instructor's resource package, and a student workbook for a course in agricultural production and management as it relates to crop production. The module contains 17 units of instruction, each of which contains some or all of the following components: objective sheet, instructor's guide, information…

Oral Hygiene. Learning Activity Package.

ERIC Educational Resources Information Center

Hime, Kirsten

This learning activity package on oral hygiene is one of a series of 12 titles developed for use in health occupations education programs. Materials in the package include objectives, a list of materials needed, a list of definitions, information sheets, reviews (self evaluations) of portions of the content, and answers to reviews. These topics…

Custom Sewing, Modules One, Two, and Three. Instructor Guide.

ERIC Educational Resources Information Center

Missouri Univ., Columbia. Instructional Materials Lab.

This document consists of three modules designed for a custom apparel and garment sewing program teaching students to construct, alter, and prepare garments and home fashions to customer specifications. Each module includes some or all of the following components: performance objectives, lesson plans, suggested activities, information sheets,…

Grooming. Learning Activity Package.

ERIC Educational Resources Information Center

Stark, Pamela

This learning activity package on grooming for health workers is one of a series of 12 titles developed for use in health occupations education programs. Materials in the package include objectives, a list of materials needed, information sheets, reviews (self evaluations) of portions of the content, and answers to reviews. These topics are…

Army FY 1999 Financial Reporting of Conventional Ammunition

DTIC Science & Technology

2000-09-01

financial reporting of operating materials and supplies. This report discusses the Army reporting of conventional ammunition, which is a material part of the Army operating materials and supplies. In general, conventional ammunition consists of any item containing explosives. At $18.9 billion, conventional ammunition, reported as operating materials and supplies, represented 26 percent of the $72.3 billion in total assets that the Army reported and was the largest tangible asset amount on the balance sheet. Objectives. The overall objective of our audit was to obtain

Undergraduate Electronics Projects Based on the Design of an Optical Wireless Audio Transmission System

ERIC Educational Resources Information Center

Oliveira, Luis Bica; Paulino, Nuno; Oliveira, João P.; Santos-Tavares, Rui; Pereira, Nuno; Goes, João

2017-01-01

The two projects presented in this paper can be used either as two separate assignments in two different semesters or as a final assignment for undergraduate students of electrical engineering. They have two main objectives: first, to teach basic electronic circuit design concepts and, second, to motivate the students to learn more about analog…

75 FR 63780 - Fisheries of the Caribbean, Gulf of Mexico, and South Atlantic; Reef Fish Fishery of the Gulf of...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-18

... objective of the 2009 Southeast Data, Assessment, and Review (SEDAR) update assessment for Gulf red grouper... resulted from the discard sizes for headboats, which were assigned using headboat observer data, and the discard sizes for the private and charter boats, which were assigned using a combination of the Mote...

Delivery versus Time Devoted to Assignments: The Effect on Course Performance

ERIC Educational Resources Information Center

Guidry, Krisandra

2017-01-01

Research in the area of amount of time spent on assignments and effect on course performance has focused exclusively either on the lecture or online format, but not comparison of the two. Nowhere has both modes of delivery been studied using an objective measure of course involvement. This study examines what is most significant in predicting a…

ConfChem Conference on Select 2016 BCCE Presentations: Specifications Grading in the Flipped Organic Classroom

ERIC Educational Resources Information Center

Ring, Joshua

2017-01-01

Specifications Grading is a system of course-long student assessment based on the division of learning objectives into clearly defined skill tests or assignments. Each skill is evaluated at a mastery level, with opportunities for students to learn from their mistakes and then be re-evaluated for skill tests, or resubmit assignments. Specifications…

Software Method for Computed Tomography Cylinder Data Unwrapping, Re-slicing, and Analysis

NASA Technical Reports Server (NTRS)

Roth, Don J.

2013-01-01

A software method has been developed that is applicable for analyzing cylindrical and partially cylindrical objects inspected using computed tomography (CT). This method involves unwrapping and re-slicing data so that the CT data from the cylindrical object can be viewed as a series of 2D sheets (or flattened onion skins ) in addition to a series of top view slices and 3D volume rendering. The advantages of viewing the data in this fashion are as follows: (1) the use of standard and specialized image processing and analysis methods is facilitated having 2D array data versus a volume rendering; (2) accurate lateral dimensional analysis of flaws is possible in the unwrapped sheets versus volume rendering; (3) flaws in the part jump out at the inspector with the proper contrast expansion settings in the unwrapped sheets; and (4) it is much easier for the inspector to locate flaws in the unwrapped sheets versus top view slices for very thin cylinders. The method is fully automated and requires no input from the user except proper voxel dimension from the CT experiment and wall thickness of the part. The software is available in 32-bit and 64-bit versions, and can be used with binary data (8- and 16-bit) and BMP type CT image sets. The software has memory (RAM) and hard-drive based modes. The advantage of the (64-bit) RAM-based mode is speed (and is very practical for users of 64-bit Windows operating systems and computers having 16 GB or more RAM). The advantage of the hard-drive based analysis is one can work with essentially unlimited-sized data sets. Separate windows are spawned for the unwrapped/re-sliced data view and any image processing interactive capability. Individual unwrapped images and un -wrapped image series can be saved in common image formats. More information is available at http://www.grc.nasa.gov/WWW/OptInstr/ NDE_CT_CylinderUnwrapper.html.

Podcasts as Tools in Introductory Environmental Studies

PubMed Central

Vatovec, Christine; Balser, Teri

2009-01-01

Technological tools have increasingly become a part of the college classroom, often appealing to teachers because of their potential to increase student engagement with course materials. Podcasts in particular have gained popularity as tools to better inform students by providing access to lectures outside of the classroom. In this paper, we argue that educators should expand course materials to include prepublished podcasts to engage students with both course topics and a broader skill set for evaluating readily available media. We present a pre- and postassignment survey evaluation assessing student preferences for using podcasts and the ability of a podcast assignment to support learning objectives in an introductory environmental studies course. Overall, students reported that the podcasts were useful tools for learning, easy to use, and increased their understanding of course topics. However, students also provided insightful comments on visual versus aural learning styles, leading us to recommend assigning video podcasts or providing text-based transcripts along with audio podcasts. A qualitative analysis of survey data provides evidence that the podcast assignment supported the course learning objective for students to demonstrate critical evaluation of media messages. Finally, we provide recommendations for selecting published podcasts and designing podcast assignments. PMID:23653686

Designing and Developing Web-Based Administrative Tools for Program Management

NASA Technical Reports Server (NTRS)

Gutensohn, Michael

2017-01-01

The task assigned for this internship was to develop a new tool for tracking projects, their subsystems, the leads, backups, and other employees assigned to them, as well as all the relevant information related to the employee (WBS (time charge) codes, time distribution, certifications, and assignments). Currently, this data is tracked manually using a number of different spreadsheets and other tools simultaneously by a number of different people; some of these documents are then merged into one large document. This often leads to inconsistencies and loss in data due to human error. By simplifying the process of tracking this data and aggregating it into a single tool, it is possible to significantly decrease the potential for human error and time spent collecting and checking this information. II. Objective The main objective of this internship is to develop a web-based tool using Ruby on Rails to serve as a method of easily tracking projects, subsystems, and points of contact, along with employees, their assignments, time distribution, certifications, and contact information. Additionally, this tool must be capable of generating a number of different reports based on the data collected. It was important that this tool deliver all of this information using a readable and intuitive interface.

Teaching Undergraduate Students to Visualize and Communicate Public Health Data with Infographics

PubMed Central

Shanks, Justin D.; Izumi, Betty; Sun, Christina; Martin, Allea; Byker Shanks, Carmen

2017-01-01

The purpose of this study was to explore the degree to which an infographic assignment facilitated student learning around health science issues, as well as the ways in which the assignment was an effective teaching tool. The objectives of the assignment were to (1) understand the purposes of and potential uses for infographics, (2) cultivate creative visual communication skills, and (3) disseminate a complex health topic to diverse audiences. The infographic assignment was developed at Montana State University and piloted at Portland State University. Students were assigned to small groups of three or four to create an infographic focused on a health science issue. The assignment was divided into four steps: brainstorming, developing, designing, and finalizing. Focus groups were conducted to assess how learning occurred throughout the assignment and identify any opportunities for modification of the assignment. This study was conducted with freshman students enrolled at Portland State University, a public university located in downtown Portland, OR, USA. Thirty four students completed the assignment and 31 students participated in one of three focus groups. Four themes emerged from focus groups: (1) Communicating Science-Related Topics to Non-experts, (2) Developing Professional Skills, (3) Understanding Health Issues, and (4) Overall Experience. This article outlines the assignment, discusses focus group results, and presents assignment modifications. It is clear that the infographic assignment facilitated learning about accessing and translating data. This assignment is ideally suited for use with diverse college-age audiences in health education and health promotion fields. PMID:29226120

Teaching Undergraduate Students to Visualize and Communicate Public Health Data with Infographics.

PubMed

Shanks, Justin D; Izumi, Betty; Sun, Christina; Martin, Allea; Byker Shanks, Carmen

2017-01-01

The purpose of this study was to explore the degree to which an infographic assignment facilitated student learning around health science issues, as well as the ways in which the assignment was an effective teaching tool. The objectives of the assignment were to (1) understand the purposes of and potential uses for infographics, (2) cultivate creative visual communication skills, and (3) disseminate a complex health topic to diverse audiences. The infographic assignment was developed at Montana State University and piloted at Portland State University. Students were assigned to small groups of three or four to create an infographic focused on a health science issue. The assignment was divided into four steps: brainstorming, developing, designing, and finalizing. Focus groups were conducted to assess how learning occurred throughout the assignment and identify any opportunities for modification of the assignment. This study was conducted with freshman students enrolled at Portland State University, a public university located in downtown Portland, OR, USA. Thirty four students completed the assignment and 31 students participated in one of three focus groups. Four themes emerged from focus groups: (1) Communicating Science-Related Topics to Non-experts, (2) Developing Professional Skills, (3) Understanding Health Issues, and (4) Overall Experience. This article outlines the assignment, discusses focus group results, and presents assignment modifications. It is clear that the infographic assignment facilitated learning about accessing and translating data. This assignment is ideally suited for use with diverse college-age audiences in health education and health promotion fields.

Multi-Objectivising Combinatorial Optimisation Problems by Means of Elementary Landscape Decompositions.

PubMed

Ceberio, Josu; Calvo, Borja; Mendiburu, Alexander; Lozano, Jose A

2018-02-15

In the last decade, many works in combinatorial optimisation have shown that, due to the advances in multi-objective optimisation, the algorithms from this field could be used for solving single-objective problems as well. In this sense, a number of papers have proposed multi-objectivising single-objective problems in order to use multi-objective algorithms in their optimisation. In this article, we follow up this idea by presenting a methodology for multi-objectivising combinatorial optimisation problems based on elementary landscape decompositions of their objective function. Under this framework, each of the elementary landscapes obtained from the decomposition is considered as an independent objective function to optimise. In order to illustrate this general methodology, we consider four problems from different domains: the quadratic assignment problem and the linear ordering problem (permutation domain), the 0-1 unconstrained quadratic optimisation problem (binary domain), and the frequency assignment problem (integer domain). We implemented two widely known multi-objective algorithms, NSGA-II and SPEA2, and compared their performance with that of a single-objective GA. The experiments conducted on a large benchmark of instances of the four problems show that the multi-objective algorithms clearly outperform the single-objective approaches. Furthermore, a discussion on the results suggests that the multi-objective space generated by this decomposition enhances the exploration ability, thus permitting NSGA-II and SPEA2 to obtain better results in the majority of the tested instances.

"Object Lesson": Using Family Heirlooms to Engage Students in Art History

ERIC Educational Resources Information Center

Rose, Marice

2012-01-01

This first written assignment of the semester for the author's undergraduate introductory art history class--an essay where students describe and reflect upon the significance of a family heirloom--is instrumental in meeting class objectives. The author's objectives in this class are for students: (1) to broaden their conception of what art is…

Do Sex, Sex-Role Orientation, and Exposure to Gender-Congruent Therapy Models Influence Receptivity to Psychotherapy?

ERIC Educational Resources Information Center

Park, Heather L.; Hatchett, Gregory T.

2006-01-01

This study had two objectives. The first objective was to evaluate how well sex and sex-role orientation predicted receptivity to psychotherapy. The second objective was to evaluate whether exposure to gender-congruent therapy videos influenced participants' receptivity to psychotherapy. Participants were randomly assigned to three conditions: (1)…

Ability of College Students to Simulate ADHD on Objective Measures of Attention

ERIC Educational Resources Information Center

Booksh, Randee Lee; Pella, Russell D.; Singh, Ashvind N.; Gouvier, William Drew

2010-01-01

Objective: The authors examined the ability of college students to simulate ADHD symptoms on objective and self-report measures and the relationship between knowledge of ADHD and ability to simulate ADHD. Method: Undergraduate students were assigned to a control or a simulated ADHD malingering condition and compared with a clinical AD/HD group.…

Teaching Mediated Public Relations.

ERIC Educational Resources Information Center

Kent, Michael L.

2001-01-01

Discusses approaches to teaching a mediated public relations course, emphasizing the World Wide Web. Outlines five course objectives, assignments and activities, evaluation, texts, and lecture topics. Argues that students mastering these course objectives will understand ethical issues relating to media use, using mediated technology in public…

Large scale superres 3D imaging: light-sheet single-molecule localization microscopy (Conference Presentation)

NASA Astrophysics Data System (ADS)

Lu, Chieh Han; Chen, Peilin; Chen, Bi-Chang

2017-02-01

Optical imaging techniques provide much important information in understanding life science especially cellular structure and morphology because "seeing is believing". However, the resolution of optical imaging is limited by the diffraction limit, which is discovered by Ernst Abbe, i.e. λ/2(NA) (NA is the numerical aperture of the objective lens). Fluorescence super-resolution microscopic techniques such as Stimulated emission depletion microscopy (STED), Photoactivated localization microscopy (PALM), and Stochastic optical reconstruction microscopy (STORM) are invented to have the capability of seeing biological entities down to molecular level that are smaller than the diffraction limit (around 200-nm in lateral resolution). These techniques do not physically violate the Abbe limit of resolution but exploit the photoluminescence properties and labelling specificity of fluorescence molecules to achieve super-resolution imaging. However, these super-resolution techniques limit most of their applications to the 2D imaging of fixed or dead samples due to the high laser power needed or slow speed for the localization process. Extended from 2D imaging, light sheet microscopy has been proven to have a lot of applications on 3D imaging at much better spatiotemporal resolutions due to its intrinsic optical sectioning and high imaging speed. Herein, we combine the advantage of localization microscopy and light-sheet microscopy to have super-resolved cellular imaging in 3D across large field of view. With high-density labeled spontaneous blinking fluorophore and wide-field detection of light-sheet microscopy, these allow us to construct 3D super-resolution multi-cellular imaging at high speed ( minutes) by light-sheet single-molecule localization microscopy.

A useful method to overcome the difficulties of applying silicone gel sheet on irregular surfaces.

PubMed

Grella, Roberto; Nicoletti, Gianfranco; D'Ari, Antonio; Romanucci, Vincenza; Santoro, Mariangela; D'Andrea, Francesco

2015-04-01

To date, silicone gel and silicone occlusive plates are the most useful and effective treatment options for hypertrophic scars (surgical and traumatic). Use of silicone sheeting has also been demonstrated to be effective in the treatment of minor keloids in association with corticosteroid intralesional infiltration. In our practice, we encountered four problems: maceration, rashes, pruritus and infection. Not all patients are able to tolerate the cushion, especially children, and certain anatomical regions as the face and the upper chest are not easy to dress for obvious social, psychological and aesthetic reasons. In other anatomical regions, it is also difficult to obtain adequate compression and occlusion of the scar. To overcome such problems of applying silicone gel sheeting, we tested the use of liquid silicone gel (LSG) in the treatment of 18 linear hypertrophic scars (HS group) and 12 minor keloids (KS group) as an alternative to silicone gel sheeting or cushion. Objective parameters (volume, thickness and colour) and subjective symptoms such as pain and pruritus were examined. Evaluations were made when the therapy started and after 30, 90 and 180 days of follow-up. After 90 days of treatment with silicone gel alone (two applications daily), HS group showed a significant improvement in terms of volume decrease, reduced inflammation and redness and improved elasticity. In conclusion, on the basis of our clinical data, we find LSG to be a useful method to overcome the difficulties of applying silicone gel sheeting on irregular surface. © 2013 The Authors. International Wound Journal © 2013 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

BOOK REVIEW: Key Science Physics: New Edition and Key Science Physics for International Schools: Extension File

NASA Astrophysics Data System (ADS)

Maybank, Maureen

1999-09-01

When handling , I recalled how one set of sixth-form students that I taught affectionately referred to Jim Breithaupt's large format book Understanding Physics for Advanced Level as `Big Jim'. This package, for GCSE students and teachers, is its younger brother. Key Science Physics was reviewed in this journal over four years ago. Now it is in a new edition with an expanded ring file of teacher resources (a Teacher's Guide and Extension File). It has been expanded for a wider range of students to meet the requirements of all GCSE syllabuses with additional topics for IGCSE and IB. The international bit seems to be among materials in the file of resources and does not appear in the title of the students' textbook. This is not one of those purchases that will only get occasional use and be left in a department library but it is one that contains sufficient excellent material to become central to any GCSE Physics course. For the students there is a single-volume 396-page textbook in full colour (not a heavyweight book). Marginal comments point out places where an Activity or Assignment from the Extension File fits in. All the materials in the teacher's Extension File are cross referenced to the numbering of this textbook, i.e. its Themes, Topics, Checkpoints, Tests etc, not to page numbers. The margin is used in other attractive ways to highlight a summary, propose a first thought or provide a topic summary. The text is fruitful mix of pure physics, applications and personalities. To support the students' practical work the Extension File contains photocopiable sheets. For the activities and assignments a few contain a harder version to give access to the higher levels of attainment. Four alternatives to practical questions are given; there are also exam questions and multiple choice questions for each topic. These all have helpful mark schemes on the teacher's answers pages. What else do you get? A Glossary collection of sheets to photocopy with space to enter a definition in a second language. Versions of many key diagrams in the student book are enlarged and reworked in clear black and white to make OHP transparencies. There is a mention of these also being in colour on a CD-ROM. The organization of the Extension File is as clear as is reasonably possible. As a user, I would add coloured page dividers to mark the sections within it. The Teacher's Guide is admirable in its restraint - just 26 sides of topic notes - which includes the answers to the non-numerical checkpoint questions missing in the student book. It is not wordy or full of educational theory but succinct and relevant to the day-to-day business of learning with these materials. Reading it, I was aware of the snags that a novice teacher might be glad to know but were missing. As always, materials like these should come with a health warning - try out all homework sheets, instructions for activities and assignments before your students!

Production and characterization of novel starch and poly(butylene adipate-co-terephthalate)-based materials and their applications

NASA Astrophysics Data System (ADS)

Stagner, Jacqueline Ann

This work focuses on the production and characterization of blends of maleated thermoplastic starch (MTPS) and poly(butylenes adipate-co-terephthalate) and their application for use as thermoformed objects, films, and foams. First, by the production and characterization of maleated thermoplastic starch (MTPS) synthesized by reactive extrusion in a twin-screw extruder, a better understanding of MTPS was gained. This reactive thermoplastic starch was prepared with glycerol as the plasticizer, maleic anhydride (MA), and free-radical initiator, 2,5-bis(tert-butylperoxy)-2,5-dimethylhexane (Luperox 101). Dynamic light scattering (DLS), differential scanning calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR), soxhlet extraction in acetone, and environmental scanning electron microscopy (ESEM) were performed to determine the effect of maleation, extrusion temperature, initiator concentration, and maleic anhydride concentration on the resulting MTPS. Next, maleated thermoplastic starch (MTPS) and thermoplastic starch (TPS) were reactively blended in a twin-screw extruder with a biodegradable polyester, poly(butylene adipate-co-terephthalate) (PBAT). The blends were extruded to produce thermoformable sheets. The mechanical properties of the sheets were characterized by tensile and puncture tests. Proof of grafting was determined by soxhlet extraction in dichloromethane and FTIR analysis. Observations of the thermal properties were made using DSC, while the surface of the sheets was imaged using ESEM. Blends of MTPS and PBAT were also extruded to produce films. Mechanical testing (tensile and puncture tests) and barrier performance testing (carbon dioxide, oxygen, and water vapor permeability) were performed on the films. Transmission electron microscopy (TEM) was used to image the blends and to view the dispersion of the various phases. Finally, blends of MTPS and PBAT were extruded with an endothermic chemical blowing agent to produce foams. The foams were characterized by measuring density, expansion ratio, specific length, compressive strength, resiliency, and moisture sorption. Also, digital light microscopy was used to image the cell structure of the foams. This work demonstrates that blends of starch and PBAT can be produced and formed into thermoformed objects, films, and foams. These objects can replace current objects made from non-biodegradable, petroleum-based plastics. By blending the starch and PBAT together, one receives advantages over using either component separately.

Learning Bridge Tool to Improve Student Learning, Preceptor Training, and Faculty Teamwork

PubMed Central

Cawley, Pauline; Arendt, Cassandra S.

2011-01-01

Objectives To implement a Learning Bridge tool to improve educational outcomes for pharmacy students as well as for preceptors and faculty members. Design Pharmacy faculty members collaborated to write 9 case-based assignments that first-year pharmacy (P1) students worked with preceptors to complete while at experiential sites. Assessment Students, faculty members, and preceptors were surveyed about their perceptions of the Learning Bridge process. As in our pilot study,1 the Learning Bridge process promoted student learning. Additionally, the Learning Bridge assignments familiarized preceptors with the school's P1 curriculum and its content. Faculty teamwork also was increased through collaborating on the assignments. Conclusions The Learning Bridge assignments provided a compelling learning environment and benefited students, preceptors, and faculty members. PMID:21655400

Evidence for two interconverting protein isomers in the methotrexate complex of dihydrofolate reductase from Escherichia coli

DOE Office of Scientific and Technical Information (OSTI.GOV)

Falzone, C.J.; Benkovic, S.J.; Wright, P.E.

1991-02-26

Two-dimensional {sup 1}H NMR methods and a knowledge of the X-ray crystal structure have been used to make resonance assignments for the amino acid side chains of dihydrofolate reductase from Escherichia coli complexed with methotrexate. The H7 proton on the pteridine ring of methotrexate was found to have NOEs to the methyl protons of Leu-28 which were assigned by using the L28F mutant. These NOEs indicated that the orientation of the methotrexate pteridine ring is similar in both solution and crystal structures. During the initial assignment process, it became evident that many of the resonances in this complex, unlike thosemore » of the folate complex, are severally broadened or doubled. The observation of two distinct sets of resonances in a ratio of approximately 2:1 was attributed to the presence of two protein isomers. Many of the side chains with clearly doubled resonances were located in the {beta}-sheet and the active site. Preliminary studies on the apoprotein also revealed doubled resonances in the absence of the inhibitor, indicating the existence of the protein isomers prior to methotrexate binding. In contrast to the methotrexate complex, the binary complex with folate and the ternary MTX-NADPH-DHFR complex presented a single enzyme form. These results are proposed to reflect the ability of folate and NADPH to bind predominantly to one protein isomer.« less

Conflict Resolution Unit.

ERIC Educational Resources Information Center

Busselle, Tish

This 7-day unit, intended for use with secondary students, contains a statement of rationale and objectives, lesson plans, class assignments, teacher and student bibliographies, and suggestions for instructional materials on conflict resolution between individuals, groups, and nations. Among the six objectives listed for the unit are: 1) explain…

Directory of research projects, 1991. Planetary geology and geophysics program

NASA Technical Reports Server (NTRS)

Maxwell, Ted A. (Editor)

1991-01-01

Information is provided about currently funded scientific research within the Planetary Geology and Geophysics Program. The directory consists of the proposal summary sheet from each proposal funded by the program during fiscal year 1991. Information is provided on the research topic, principal investigator, institution, summary of research objectives, past accomplishments, and proposed investigators.

The Gould-Wysinger Awards: A Tradition of Excellence. Fact Sheet #44.

ERIC Educational Resources Information Center

Goodnow, Michael

A primary goal of the Office of Juvenile Justice and Delinquency Prevention (OJJDP) is to identify and promote programs that enhance the field of juvenile justice. Since 1992, the Gould-Wysinger Awards, commemorating two OJJDP professionals, have recognized programs that advance the objectives of the Juvenile Justice and Delinquency Prevention Act…

Four Day School Week for Small Rural Schools. Small Schools Fact Sheet.

ERIC Educational Resources Information Center

Culbertson, Jeanne

The four-day school week is a Monday-Thursday or Tuesday-Friday alternative to the traditional four-day week, which can be implemented with many variables and differing objectives. The four-day week saves heating, transportation, maintenance, electricity and some instructional costs, while providing better educational opportunities and use of…

76 FR 51060 - Guidelines for Ensuring and Maximizing the Quality, Objectivity, Utility, and Integrity of...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-08-17

... Science Foundation specify that the agency ``may reject claims made in bad faith, or without justification... communication or representation of facts or data in any medium or form including textual, numerical... individuals or persons. Press releases, fact sheets, press conferences, or similar communications in any...

Electrical Experiments. VT-214-12-3. Part III. Basic Electronics.

ERIC Educational Resources Information Center

Connecticut State Dept. of Education, Hartford. Div. of Vocational Education.

Designed for high school electronics students, this third document in a series of six electrical learning activity packages focuses on basic electronics. An introductory section gives the objective for the activities, an introduction, and an outline of the content. The remainder of the activity book is comprised of information sheets and job…

Biotechnology in Agriculture. Teacher Edition.

ERIC Educational Resources Information Center

Peterson, Dennis R.; Rehberger, Thomas

This curriculum guide is designed to help teachers to present a course that emphasizes the interrelationship of science and technology and the impact of this technology on agriculture and agricultural products. The guide contains six units that each contain some or all of the following basic components of a unit of instruction: objective sheet,…

Automatic Transmission/Transaxle Specialist. Instructor Manual and Student Workbook. Automotive Service Series.

ERIC Educational Resources Information Center

Oklahoma State Dept. of Vocational and Technical Education, Stillwater. Curriculum and Instructional Materials Center.

This curriculum guide for transmission/transaxle specialist is one in a series of automotive service speciality publications that is based on the National Institute of Automotive Service Excellence task lists. The curriculum contains nine units. Each unit of instruction includes some or all of the following components: objective sheet,…

Directory of research projects: Planetary geology and geophysics program

NASA Technical Reports Server (NTRS)

Holt, Henry (Editor)

1990-01-01

Information about currently funded scientific research within the Planetary Geology and Geophysics Program is provided, including the proposal summary sheet from each proposal funded under the program during fiscal year 1990. Information about the research project, including title, principal investigator, institution, summary of research objectives, past accomplishments, and proposed new investigations is also provided.

14 CFR 6 - Objective Classification of Balance Sheet Elements

Code of Federal Regulations, 2012 CFR

2012-01-01

...] Current Liabilities 2000Current Maturities of Long-term Debt. Record here the face value or principal... not properly classifiable as current. 2005Notes Payable—Banks. Record here the face value of all notes... should be included in account 2000. 2015Notes Payable—Other. Record here the face value of all notes...

14 CFR Section 6 - Objective Classification of Balance Sheet Elements

Code of Federal Regulations, 2014 CFR

2014-01-01

...] Current Liabilities 2000Current Maturities of Long-term Debt. Record here the face value or principal... not properly classifiable as current. 2005Notes Payable—Banks. Record here the face value of all notes... should be included in account 2000. 2015Notes Payable—Other. Record here the face value of all notes...

14 CFR Section 6 - Objective Classification of Balance Sheet Elements

Code of Federal Regulations, 2013 CFR

2013-01-01

...] Current Liabilities 2000Current Maturities of Long-term Debt. Record here the face value or principal... not properly classifiable as current. 2005Notes Payable—Banks. Record here the face value of all notes... should be included in account 2000. 2015Notes Payable—Other. Record here the face value of all notes...

Fuel Cell Technology Status Analysis Project: Partnership Opportunities

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fact sheet describing the National Renewable Energy Laboratory's (NREL's) Fuel Cell Technology Status Analysis Project. NREL is seeking fuel cell industry partners from the United States and abroad to participate in an objective and credible analysis of commercially available fuel cell products to benchmark the current state of the technology and support industry growth.

The Surgical Scrub. Learning Activity Package.

ERIC Educational Resources Information Center

Runge, Lillian

This learning activity package on the surgical scrub is one of a series of 12 titles developed for use in health occupations education programs. Materials in the package include objectives, a list of materials needed, a list of definitions, information sheets, reviews (self evaluations) of portions of the content, and answers to reviews. These…

Nonaerodynamic sabot stripper for research gas gun

NASA Astrophysics Data System (ADS)

Mock, W., Jr.; Holt, W. H.

1994-07-01

A nonaerodynamic sabot stripper has been designed and implemented for use with a 40.00-mm smooth bore research gas gun. The stripper consists of several metal parts to stop and contain the sabot while allowing the carried object to pass unhindered through it. The single-piece sabot is stopped by impacting replaceable layers of 19-mm-thick aluminum and steel plates and 3.2-mm-thick rubber sheets. The metal plates and rubber sheets have 25.4- and 31.8-mm diam holes, respectively, for passage of the carried object. The sabot stripper is located 230 mm from the muzzle of the gas gun and is aligned before each shot using a special metal fixture that is inserted into the gun muzzle. Cubes measuring 12.7 mm have been launched in a flat-faced orientation. Targets consisting of 76.2 mm×76.2 mm plates of various thicknesses are positioned in an assembly that attaches to the sabot stripper and is located 57 mm behind it. The velocity range for the experiments was from 0.61 to 0.94 km/s.

Sheet-like assemblies of spherical particles with point-symmetrical patches.

PubMed

Mani, Ethayaraja; Sanz, Eduardo; Roy, Soumyajit; Dijkstra, Marjolein; Groenewold, Jan; Kegel, Willem K

2012-04-14

We report a computational study on the spontaneous self-assembly of spherical particles into two-dimensional crystals. The experimental observation of such structures stabilized by spherical objects appeared paradoxical so far. We implement patchy interactions with the patches point-symmetrically (icosahedral and cubic) arranged on the surface of the particle. In these conditions, preference for self-assembly into sheet-like structures is observed. We explain our findings in terms of the inherent symmetry of the patches and the competition between binding energy and vibrational entropy. The simulation results explain why hollow spherical shells observed in some Keplerate-type polyoxometalates (POM) appear. Our results also provide an explanation for the experimentally observed layer-by-layer growth of apoferritin--a quasi-spherical protein.

72-directional display having VGA resolution for high-appearance image generation

NASA Astrophysics Data System (ADS)

Takaki, Yasuhiro; Dairiki, Takeshi

2006-02-01

The high-density directional display, which was originally developed in order to realize a natural 3D display, is not only a 3D display but also a high-appearance display. The appearances of objects, such as glare and transparency, are the results of the reflection and the refraction of rays. The faithful reproduction of such appearances of objects is impossible using conventional 2D displays because rays diffuse on the display screen. The high-density directional display precisely controls the horizontal ray directions so that it can reproduce the appearances of objects. The fidelity of the reproduction of object appearances depends on the ray angle sampling pitch. The angle sampling pitch is determined by considering the human eye imaging system. In the present study the high-appearance display which has the resolution of 640×400 and emits rays in 72 different horizontal directions with the angle pitch of 0.38° was constructed. Two 72-directional displays were combined, each of which consisted of a high-resolution LCD panel (3,840×2,400) and a slanted lenticular sheet. Two images produced by two displays were superimposed by a half mirror. A slit array was placed at the focal plane of the lenticular sheet for each display to reduce the horizontal image crosstalk in the combined image. The impression analysis shows that the high-appearance display provides higher appearances and presence than the conventional 2D displays do.

Concentration-dependent effects of spermine on apoptosis and consequent generation of multilayer myotube sheets from mouse embryoid bodies in vitro.

PubMed

Saito, Mikako; Abe, Natsuki; Ishida, Ayano; Nakagawa, Shota; Matsuoka, Hideaki

2014-12-01

The concentration-dependent effect of spermine was investigated on the spermine-induced generation of multilayer myotube sheets (MMTS) from mouse embryoid bodies (EBs). During spermine treatment for 24 h, a monolayer cell sheet that had already grown radially from the periphery of an EB was exfoliated. The exfoliation was inhibited by z-VAD.fmk, indicating the occurrence of apoptosis, and inhibited also by aminoguanidine, indicating the involvement of amine oxidase. Following the exfoliation, the cell growth restarted from the fresh periphery of EB in a spermine-free medium and finally formed MMTS. To analyze the contribution of apoptosis to the cell death causing exfoliation, the numbers of apoptotic, necrotic, and 2nd apoptotic cells were counted by staining with Annexin V-Cyanine-3 (AVC3) and 7-aminoactinomycin (7AAC). AVC3-positive, 7AAC-positive, and AVC3/7AAC doubly positive cells were assigned as apoptotic, necrotic, and 2nd necrotic cells, respectively. The relative number of apoptotic and 2nd necrotic cells (N A + N A/7) to the total number of dying cells (N T) was 84 ∼ 94%, which was independent of spermine concentration in the range from 0.1 to 2.0 mM. The MMTS generation rate at the final stage, however, was dependent on the spermine concentration. It was 60 ∼ 80% in the range from 0.1 to 1.5 mM, while it decreased sharply to 1% at 2 mM. This suggests another role of spermine in the MMTS generation in addition to the induction of apoptosis. This 2nd role seems to be inhibited at a spermine concentration higher than a critical limit between 1.5 and 2.0 mM.

The turbomachine blading design using S2-S1 approach

NASA Technical Reports Server (NTRS)

Luu, T. S.; Bencherif, L.; Viney, B.; Duc, J. M. Nguyen

1991-01-01

The boundary conditions corresponding to the design problem when the blades being simulated by the bound vorticity distribution are presented. The 3D flow is analyzed by the two steps S2 - S1 approach. In the first step, the number of blades is supposed to be infinite, the vortex distribution is transformed into an axisymmetric one, so that the flow field can be analyzed in a meridional plane. The thickness distribution of the blade producing the flow channel striction is taken into account by the modification of metric tensor in the continuity equation. Using the meridional stream function to define the flow field, the mass conservation is satisfied automatically. The governing equation is deduced from the relation between the azimuthal component of the vorticity and the meridional velocity. The value of the azimuthal component of the vorticity is provided by the hub to shroud equilibrium condition. This step leads to the determination of the axisymmetric stream sheets as well as the approximate camber surface of the blade. In the second step, the finite number of blades is taken into account, the inverse problem corresponding to the blade to blade flow confined in each stream sheet is analyzed. The momentum equation implies that the free vortex of the absolute velocity must be tangential to the stream sheet. The governing equation for the blade to blade flow stream function is deduced from this condition. At the beginning, the upper and the lower surfaces of the blades are created from the camber surface obtained from the first step with the assigned thickness distribution. The bound vorticity distribution and the penetrating flux conservation applied on the presumed blade surface constitute the boundary conditions of the inverse problem. The detection of this flux leads to the rectification of the geometry of the blades.

Single Machine Scheduling and Due Date Assignment with Past-Sequence-Dependent Setup Time and Position-Dependent Processing Time

PubMed Central

Zhao, Chuan-Li; Hsu, Hua-Feng

2014-01-01

This paper considers single machine scheduling and due date assignment with setup time. The setup time is proportional to the length of the already processed jobs; that is, the setup time is past-sequence-dependent (p-s-d). It is assumed that a job's processing time depends on its position in a sequence. The objective functions include total earliness, the weighted number of tardy jobs, and the cost of due date assignment. We analyze these problems with two different due date assignment methods. We first consider the model with job-dependent position effects. For each case, by converting the problem to a series of assignment problems, we proved that the problems can be solved in O(n 4) time. For the model with job-independent position effects, we proved that the problems can be solved in O(n 3) time by providing a dynamic programming algorithm. PMID:25258727

Single machine scheduling and due date assignment with past-sequence-dependent setup time and position-dependent processing time.

PubMed

Zhao, Chuan-Li; Hsu, Chou-Jung; Hsu, Hua-Feng

2014-01-01

This paper considers single machine scheduling and due date assignment with setup time. The setup time is proportional to the length of the already processed jobs; that is, the setup time is past-sequence-dependent (p-s-d). It is assumed that a job's processing time depends on its position in a sequence. The objective functions include total earliness, the weighted number of tardy jobs, and the cost of due date assignment. We analyze these problems with two different due date assignment methods. We first consider the model with job-dependent position effects. For each case, by converting the problem to a series of assignment problems, we proved that the problems can be solved in O(n(4)) time. For the model with job-independent position effects, we proved that the problems can be solved in O(n(3)) time by providing a dynamic programming algorithm.

Multi Objective Decision Analysis for Assignment Problems

DTIC Science & Technology

2011-03-01

needed data or try to get data from related databases. 2.3.8 Deterministic Analysis In order to determine an overall score for each...The views expressed in this thesis are those of the author and do not reflect the official policy or position of the Turkish Air...DECISION ANALYSIS FOR ASSIGNMENT PROBLEMS THESIS Presented to the Faculty Department of Operational Sciences Graduate School of

Bricklayer and Stonemason. U.S.O.E. 46.0102 D.O.T. 861.381, 861.781, 861.884. Student's Manual [and] Instructor's Guide.

ERIC Educational Resources Information Center

Grimes, L. A., Jr.

The student's manual in this two-part instructional kit is designed to help students in individualized courses in bricklaying and stone masonry to tie together classroom learning and on-the-job practice. The manual includes assignments, technical information, objectives that tell what the student is to learn from each assignment, and exercise…

The Benefit of Surface Uniformity for Encoding Boundary Features in Visual Working Memory

ERIC Educational Resources Information Center

Kim, Sung-Ho; Kim, Jung-Oh

2011-01-01

Using a change detection paradigm, the present study examined an object-based encoding benefit in visual working memory (VWM) for two boundary features (two orientations in Experiments 1-2 and two shapes in Experiments 3-4) assigned to a single object. Participants remembered more boundary features when they were conjoined into a single object of…

Nuclear Data Sheets for A = 70

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gürdal, G.; McCutchan, E. A.

2016-09-01

We evaluated spectroscopic data for all nuclei with mass number A = 70, and the corresponding level schemes from radioactive decay and reaction studies are presented. Since the previous evaluation, the half-life of 70Mn has been measured and excited states in 70Fe observed for the first time. Furthermore we studied the excited states in 70Ni extensively while Coulomb excitation and collinear laser spectroscopy measurements in 70Cu have allowed for firm Jπ assignments. Despite new measurements, there remain some discrepancies in half-lives of low lying states in 70Zn. New measurements have extended the knowledge of high-spin band structures in 70Ge andmore » 70As. Our evaluation supersedes the prior A = 70 evaluation of 2004Tu09.« less

Science education: A meta-analysis of major questions

NASA Astrophysics Data System (ADS)

Anderson, Ronald D.; Kahl, Stuart R.; Glass, Gene V.; Smith, Mary Lee

A multi-institutional endeavor was initiated to integrate the findings of extant research studies directed toward the major science education research questions. The research questions were selected by a largely empirical process of identifiying the most frequently researched questions in the literature. These questions were assigned to various researchers who developed coding sheets and procedures with many features in common. This article describes the overall operation of the project, the research questions identified, and some rudiments of meta-analysis. The results of the several meta-analysis are reported in the other articles of this issue of the Journal. The final article in this issue deals with research topics for which data are drawn from one or more of the separate meta-analyses.

Molecular dynamics in aluminum layered double hydroxides as studied by 1H T1ρ NMR measurements

NASA Astrophysics Data System (ADS)

Vyalikh, Anastasia; Wang, De-Yi; Wagenknecht, Udo; Heinrich, Gert; Scheler, Ulrich

2011-06-01

Proton dynamics in pristine and organically-modified layered double hydroxide has been studied by 1H T1ρ. Inverse Laplace transform with spectral resolution results in a correlation of T1ρ and chemical shift. In LDH two contributions are resolved. They are assigned to the metal hydroxides, forming the LDH sheets (4-8 ms), and mobile interlayer water (2 ms). Apparent T1ρ values of OH-protons in surfactant-modified LDH are different in dodecylbenzenesulfonate- (SDBS) and sodium octasulfonate- (C8) modified LDH. This difference is explained by the presence of water in LDH-SDBS. The effects of spin diffusion have been studied by performing 2D 1H RFDR in the LDH-SDBS.

E-tracers: A New Technique for Wireless Sensing Under Ice Sheets

NASA Astrophysics Data System (ADS)

Burrow, S.; Wadham, J. L.; Salter, M.; Barnes, R.

2009-12-01

A significant hurdle to the understanding of ice sheet basal hydrology and its coupling with ice motion is the difficulty in making in-situ measurements along a flow path. While dye tracing techniques may be used in small glaciers to determine transit times of surface melt water through the sub-glacial system, they provide no information on in situ conditions (e.g. pressure) and are ineffective at ice-sheet scale where dilution is high. The use of tethered sensor packages is complicated by the long lengths (~100’s m) and torturous path of the moulins and conduits within ice sheets. Recent attempts to pass solid objects (rubber ducks) and other sensor packages through glacial moulins have confirmed the difficultly in deploying sensors into the sub glacial environment. Here, we report the first successful deployment and recovery of compact, electronic units to moulins up to 7 km from the margin of a large land-terminating Greenland outlet. The technique uses RF (Radio Frequency) location to create an electronic tracer (an ‘e-tracer’) enabling a data-logging sensor package to be located in the pro-glacial flood plain once it has passed through the ice sheet. A number of individual packages are used in each deployment mitigating for the risk that some may become stuck within the moulin or lodge in an inaccessible part of the floodplain. In preliminary tests on the Leverett glacier in West Greenland during August 2009 we have demonstrated that this technique can be used to locate and retrieve dummy sensor packages: 50% and 20% of the dummy sensor packages introduced to moulins at 1 and 7 km from the ice sheet terminus respectively, emerged in the sub-glacial stream. It was possible to effectively detect the e-tracer units (which broadcast on 151MHz with 10mW of power) over a horizontal range of up to 5km across the pro-glacial floodplain and locate them to a high accuracy, allowing visual recognition and manual recovery. These performance statistics give this technique strong potential for investigating in-situ conditions along a flow path at ice sheet scale.

Imaging of trabecular meshwork using Bessel-Gauss light sheet with fluorescence

NASA Astrophysics Data System (ADS)

Jie Jeesmond Hong, Xun; Shinoj, V. K.; Murukeshan, V. M.; Baskaran, M.; Aung, Tin

2017-03-01

Ocular imaging technology that holds promise for both fundamental investigation and clinical detection of glaucoma is still a challenging research area. A direct view of the trabecular meshwork (TM) with high resolution is not generally possible because the iridocorneal angle region is obstructed by the sclera overlap. The best approach to observe the aqueous outflow system (AOS) is therefore to view from the opposite angle. In this research work, we developed two imaging systems for the high resolution ex vivo studies of the AOS inside porcine eye, based on a Gaussian illuminated and a digitally scanned Bessel-Gauss beam light sheet fluorescence configurations. The digitally scanned Bessel-Gauss beam is able to overcome the trade-off between the length and thickness of the Gaussian light sheet to give better imaging performance. It has adequate spatial resolution to resolve critical anatomical structures such as the TM, thereby enabling objective information about the AOS. This non-contact and non-invasive imaging methodology with excellent safety profile is expected to be well received by vision researchers and clinicians in the evaluation and management of glaucoma.

Statistical Investigation of the Effect of Process Parameters on the Shear Strength of Metal Adhesive Joints

NASA Astrophysics Data System (ADS)

Rajkumar, Goribidanur Rangappa; Krishna, Munishamaih; Narasimhamurthy, Hebbale Narayanrao; Keshavamurthy, Yalanabhalli Channegowda

2017-06-01

The objective of the work was to optimize sheet metal joining parameters such as adhesive material, adhesive thickness, adhesive overlap length and surface roughness for single lap joint of aluminium sheet shear strength using robust design. An orthogonal array, main effect plot, signal-to-noise ratio and analysis of variance were employed to investigate the shear strength of the joints. The statistical result shows vinyl ester is best candidate among other two polymers viz. epoxy and polyester due to its low viscosity value compared to other two polymers. The experiment results shows that the adhesive thickness 0.6 mm, overlap length 50 mm and surface roughness 2.12 µm for obtained maximum shear strength of Al sheet joints. The ANOVA result shows one of the most significant factors is overlap length which affect joint strength in addition to adhesive thickness, adhesive material, and surface roughness. A confirmation test was carried out as the optimal combination of parameters will not match with the any of the experiments in the orthogonal array.

Equivalent orthotropic elastic moduli identification method for laminated electrical steel sheets

NASA Astrophysics Data System (ADS)

Saito, Akira; Nishikawa, Yasunari; Yamasaki, Shintaro; Fujita, Kikuo; Kawamoto, Atsushi; Kuroishi, Masakatsu; Nakai, Hideo

2016-05-01

In this paper, a combined numerical-experimental methodology for the identification of elastic moduli of orthotropic media is presented. Special attention is given to the laminated electrical steel sheets, which are modeled as orthotropic media with nine independent engineering elastic moduli. The elastic moduli are determined specifically for use with finite element vibration analyses. We propose a three-step methodology based on a conventional nonlinear least squares fit between measured and computed natural frequencies. The methodology consists of: (1) successive augmentations of the objective function by increasing the number of modes, (2) initial condition updates, and (3) appropriate selection of the natural frequencies based on their sensitivities on the elastic moduli. Using the results of numerical experiments, it is shown that the proposed method achieves more accurate converged solution than a conventional approach. Finally, the proposed method is applied to measured natural frequencies and mode shapes of the laminated electrical steel sheets. It is shown that the method can successfully identify the orthotropic elastic moduli that can reproduce the measured natural frequencies and frequency response functions by using finite element analyses with a reasonable accuracy.

Vertex Models of Epithelial Morphogenesis

PubMed Central

Fletcher, Alexander G.; Osterfield, Miriam; Baker, Ruth E.; Shvartsman, Stanislav Y.

2014-01-01

The dynamic behavior of epithelial cell sheets plays a central role during numerous developmental processes. Genetic and imaging studies of epithelial morphogenesis in a wide range of organisms have led to increasingly detailed mechanisms of cell sheet dynamics. Computational models offer a useful means by which to investigate and test these mechanisms, and have played a key role in the study of cell-cell interactions. A variety of modeling approaches can be used to simulate the balance of forces within an epithelial sheet. Vertex models are a class of such models that consider cells as individual objects, approximated by two-dimensional polygons representing cellular interfaces, in which each vertex moves in response to forces due to growth, interfacial tension, and pressure within each cell. Vertex models are used to study cellular processes within epithelia, including cell motility, adhesion, mitosis, and delamination. This review summarizes how vertex models have been used to provide insight into developmental processes and highlights current challenges in this area, including progressing these models from two to three dimensions and developing new tools for model validation. PMID:24896108

Early Representations of Ownership

ERIC Educational Resources Information Center

Blake, Peter R.; Harris, Paul L.

2011-01-01

To navigate a world filled with private property, children must be able to assign ownership information to objects and update that information when appropriate. In this chapter, the authors propose that children include ownership as an attribute of their object representations. Children can learn about ownership attributes either by witnessing…

A robust approach towards unknown transformation, regional adjacency graphs, multigraph matching, segmentation video frames from unnamed aerial vehicles (UAV)

NASA Astrophysics Data System (ADS)

Gohatre, Umakant Bhaskar; Patil, Venkat P.

2018-04-01

In computer vision application, the multiple object detection and tracking, in real-time operation is one of the important research field, that have gained a lot of attentions, in last few years for finding non stationary entities in the field of image sequence. The detection of object is advance towards following the moving object in video and then representation of object is step to track. The multiple object recognition proof is one of the testing assignment from detection multiple objects from video sequence. The picture enrollment has been for quite some time utilized as a reason for the location the detection of moving multiple objects. The technique of registration to discover correspondence between back to back casing sets in view of picture appearance under inflexible and relative change. The picture enrollment is not appropriate to deal with event occasion that can be result in potential missed objects. In this paper, for address such problems, designs propose novel approach. The divided video outlines utilizing area adjancy diagram of visual appearance and geometric properties. Then it performed between graph sequences by using multi graph matching, then getting matching region labeling by a proposed graph coloring algorithms which assign foreground label to respective region. The plan design is robust to unknown transformation with significant improvement in overall existing work which is related to moving multiple objects detection in real time parameters.

Spore ornamentation of Haplosporidium pickfordi Barrow, 1961 (Haplosporidia), a parasite of freshwater snails in Michigan, USA.

PubMed

Burreson, E M

2001-01-01

Spore ornamentation is increasingly recognized as a key character for species differentiation and genus assignment in the phylum Haplosporidia. Unfortunately, spore ornamentation is known for only a small number of described species so it is difficult to assign most species to genera with any confidence. Scanning and transmission electron microscopy were used to determine the presence and morphology of spore ornamentation of Haplosporidium pickfordi collected from the digestive gland of the snail Physella parkeri in Douglas Lake, Michigan. Spores possess filaments that are derived from the spore wall and originate from two separate areas at the posterior end of the spore. When spores are first isolated from host tissue, filaments are fused into a sheet that wraps around the spore, passing under the opercular lid. These filaments gradually unravel when spores are held in water and after about 14 d most filaments project freely from the posterior end of the spore. The number of filaments could not be determined with certainty, but appears to be approximately nine. Filaments are 100 nm in diam. and up to 50 microm in length. The presence of spore wall-derived filaments confirms the placement of the parasite in the genus Haplosporidium.

Ion selection of charge-modified large nanopores in a graphene sheet

NASA Astrophysics Data System (ADS)

Zhao, Shijun; Xue, Jianming; Kang, Wei

2013-09-01

Water desalination becomes an increasingly important approach for clean water supply to meet the rapidly growing demand of population boost, industrialization, and urbanization. The main challenge in current desalination technologies lies in the reduction of energy consumption and economic costs. Here, we propose to use charged nanopores drilled in a graphene sheet as ion exchange membranes to promote the efficiency and capacity of desalination systems. Using molecular dynamics simulations, we investigate the selective ion transport behavior of electric-field-driven KCl electrolyte solution through charge modified graphene nanopores. Our results reveal that the presence of negative charges at the edge of graphene nanopore can remarkably impede the passage of Cl- while enhance the transport of K+, which is an indication of ion selectivity for electrolytes. We further demonstrate that this selectivity is dependent on the pore size and total charge number assigned at the nanopore edge. By adjusting the nanopore diameter and electric charge on the graphene nanopore, a nearly complete rejection of Cl- can be realized. The electrical resistance of nanoporous graphene, which is a key parameter to evaluate the performance of ion exchange membranes, is found two orders of magnitude lower than commercially used membranes. Our results thus suggest that graphene nanopores are promising candidates to be used in electrodialysis technology for water desalinations with a high permselectivity.

Radio-echo sounding at Dome C, East Antarctica: A comparison of measured and modeled data

NASA Astrophysics Data System (ADS)

Winter, Anna; Eisen, Olaf; Steinhage, Daniel; Zirizzotti, Achille; Urbini, Stefano; Cavitte, Marie; Blankenship, Donald D.; Wolff, Eric

2016-04-01

The internal layering architecture of ice sheets, detected with radio-echo sounding (RES), contains clues to past ice-flow dynamics and mass balance. A common way of relating the recorded travel time of RES reflections to depth is by integrating a wave-speed distribution. This results in an increasing absolute error with depth. We present a synchronization of RES-internal layers of different radar systems (Alfred Wegener Institute, Center for Remote Sensing of Ice Sheets, Istituto Nazionale di Geofisica e Vulcanologia, British Antarctic Survey and University of Texas Institute for Geophysics) with ice-core records from the Antarctic deep drill site Dome C. Synthetic radar traces are obtained from measurements of ice-core density and conductivity with a 1D model of Maxwell's equations. The reflection peaks of the different radar systems' measurements are shifted by a wiggle-matching algorithm, so they match the synthetic trace. In this way, we matched pronounced internal reflections in the RES data to conductivity peaks with considerably smaller depth uncertainties, and assigned them with the ice-core age. We examine the differences in shifts and resolution of the different RES data to address the question of their comparability and combined analysis for an extensive age-depth distribution.

Time needed to achieve completeness and accuracy in bedside lung ultrasound reporting in intensive care unit.

PubMed

Tutino, Lorenzo; Cianchi, Giovanni; Barbani, Francesco; Batacchi, Stefano; Cammelli, Rita; Peris, Adriano

2010-08-12

The use of lung ultrasound (LUS) in ICU is increasing but ultrasonographic patterns of lung are often difficult to quantify by different operators. The aim of this study was to evaluate the accuracy and quality of LUS reporting after the introduction of a standardized electronic recording sheet. Intensivists were trained for LUS following a teaching programme. From April 2008, an electronic sheet was designed and introduced in ICU database in order to uniform LUS examination reporting. A mark from 0 to 24 has been given for each exam by two senior intensivists not involved in the survey. The mark assigned was based on completeness of a precise reporting scheme, concerning the main finding of LUS. A cut off of 15 was considered sufficiency. The study comprehended 12 months of observations and a total of 637 LUS. Initially, although some improvement in the reports completeness, still the accuracy and precision of examination reporting was below 15. The time required to reach a sufficient quality was 7 months. A linear trend in physicians progress was observed. The uniformity in teaching programme and examinations reporting system permits to improve the level of completeness and accuracy of LUS reporting, helping physicians in following lung pathology evolution.

Structural effects of simvastatin on liver rate tissue: Fourier transform infrared and Raman microspectroscopic studies

NASA Astrophysics Data System (ADS)

Garip, Sebnem; Bayari, Sevgi Haman; Severcan, Mete; Abbas, Sherif; Lednev, Igor K.; Severcan, Feride

2016-02-01

Simvastatin is one of the most frequently prescribed statins because of its efficacy in the treatment of hypercholesterolemia, reducing cardiovascular risk and related mortality. Determination of its side effects on different tissues is mandatory to improve safe use of this drug. In the present study, the effects of simvastatin on molecular composition and structure of healthy rat livers were investigated by Fourier transform infrared and Raman imaging. Simvastatin-treated groups received 50 mg/kg/day simvastatin for 30 days. The ratio of the area and/or intensity of the bands assigned to lipids, proteins, and nucleic acids were calculated to get information about the drug-induced changes in tissues. Loss of unsaturation, accumulation of end products of lipid peroxidation, and alterations in lipid-to-protein ratio were observed in the treated group. Protein secondary structure studies revealed significant decrease in α-helix and increase in random coil, while native β-sheet decreases and aggregated β-sheet increases in treated group implying simvastatin-induced protein denaturation. Moreover, groups were successfully discriminated using principal component analysis. Consequently, high-dose simvastatin treatment induces hepatic lipid peroxidation and changes in molecular content and protein secondary structure, implying the risk of liver disorders in drug therapy.

Incorporating Floating Surface Objects into a Fully Dispersive Surface Wave Model

DTIC Science & Technology

2016-04-19

surface objects Sigma -coordinate Navier-Stokes Finite volume Immersed boundary a b s t r a c t The shock-capturing, non-hydrostatic, three...ontaining object or fluid, respectively. A 3D object with geometry escribed in Cartesian coordinates ( x, y, z ) was first projected onto he NHWAVE...17) . Specifically, the mask values re assigned by ASK = 0 if object projection includes u , v point (i, j) and k = k b ∼ k t ASK = 1 otherwise

Rapid Freeform Sheet Metal Forming: Technology Development and System Verification

DOE Office of Scientific and Technical Information (OSTI.GOV)

Kiridena, Vijitha; Verma, Ravi; Gutowski, Timothy

The objective of this project is to develop a transformational RApid Freeform sheet metal Forming Technology (RAFFT) in an industrial environment, which has the potential to increase manufacturing energy efficiency up to ten times, at a fraction of the cost of conventional technologies. The RAFFT technology is a flexible and energy-efficient process that eliminates the need for having geometry-specific forming dies. The innovation lies in the idea of using the energy resource at the local deformation area which provides greater formability, process control, and process flexibility relative to traditional methods. Double-Sided Incremental Forming (DSIF), the core technology in RAFFT, ismore » a new concept for sheet metal forming. A blank sheet is clamped around its periphery and gradually deformed into a complex 3D freeform part by two strategically aligned stylus-type tools that follow a pre-described toolpath. The two tools, one on each side of the blank, can form a part with sharp features for both concave and convex shapes. Since deformation happens locally, the forming force at any instant is significantly decreased when compared to traditional methods. The key advantages of DSIF are its high process flexibility, high energy-efficiency, low capital investment, and the elimination of the need for massive amounts of die casting and machining. Additionally, the enhanced formability and process flexibility of DSIF can open up design spaces and result in greater weight savings.« less

Development of powder metallurgy 2XXX series Al alloy plate and sheet materials for high temperature aircraft structural applications, FY 1983/1984

NASA Technical Reports Server (NTRS)

Chellman, D. J.

1985-01-01

The objective of this investigation is to fabricate and evaluate PM 2124 Al alloy plate and sheet materials according to NASA program goals for damage tolerance and fatigue resistance. Previous research has indicated the outstanding strength-toughness relationship available with PM 2124 Al-Zr modified alloy compositions in extruded product forms. The range of processing conditions was explored in the fabrication of plate and sheet gage materials, as well as the resultant mechanical and metallurgical properties. The PM composition based on Al-3.70 Cu-1.85 Mg-0.20 Mn with 0.60 wt. pct. Zr was selected. Flat rolled material consisting of 0.250 in. thick plate was fabricated using selected thermal mechanical treatments (TMT). The schedule of TMT operations was designed to yield the extreme conditions of grain structure normally encountered in the fabrication of flat rolled products, specifically recrystallized and unrecrystallized. The PM Al alloy plate and sheet materials exhibited improved strength properties at thin gages compared to IM Al alloys, as a consequence of their enhanced ability to inhibit recrystallization and grain growth. In addition, the PM 2124 Al alloys offer much better combinations of strength and toughnessover equivalent IM Al. The alloy microstructures were examined by optical metallographic texture techniques in order to establish the metallurgical basis for these significant property improvements.

Laboratory reconnection experiments

NASA Astrophysics Data System (ADS)

Grulke, Olaf

Laboratory experiments dedicated for the study of magnetic reconnection have been contributed considerably to a more detailed understanding of the involved processes. Their strength is to disentangle parameter dependencies, to diagnose in detail the plasma and field response, and to form an excellent testbed for the validation of numerical simulations. In the present paper recent results obtained from the new cylindrical reconnection experiment VINETA II are presented. The experimental setup allows to independently vary plasma parameters, reconnection drive strength/timescale, and current sheet amplitude. Current research objectives focus on two major scientific issues: Guide field effects on magnetic reconnection and the evolution of electromagnetic fluctuations. The superimposed homogeneous magnetic guide field has a strong influence on the spatiotemporal evolution of the current sheet, predominantly due to magnetic pitch angle effects, which leads to a strong elongation of the sheet along the separatrices and results in axial gradients of the reconnection rates. Within the current sheet, incoherent electromagnetic fluctuations are observed. Their magnetic signature is characterized by a broad spectrum somewhat centered around the lower-hybrid frequency and extremely short spatial correlation lengths being typically smaller than the local ion sound radius. The fluctuation amplitude correlates with the local current density and, thus, for low guide fields, displays also axial gradients. Despite the quantitatively different parameter regime and geometry the basic fluctuation properties are in good agreement with studies conducted at the MRX experiment (PPPL).

A light sheet confocal microscope for image cytometry with a variable linear slit detector

NASA Astrophysics Data System (ADS)

Hutcheson, Joshua A.; Khan, Foysal Z.; Powless, Amy J.; Benson, Devin; Hunter, Courtney; Fritsch, Ingrid; Muldoon, Timothy J.

2016-03-01

We present a light sheet confocal microscope (LSCM) capable of high-resolution imaging of cell suspensions in a microfluidic environment. In lieu of conventional pressure-driven flow or mechanical translation of the samples, we have employed a novel method of fluid transport, redox-magnetohydrodynamics (redox-MHD). This method achieves fluid motion by inducing a small current into the suspension in the presence of a magnetic field via electrodes patterned onto a silicon chip. This on-chip transportation requires no moving parts, and is coupled to the remainder of the imaging system. The microscopy system comprises a 450 nm diode 20 mW laser coupled to a single mode fiber and a cylindrical lens that converges the light sheet into the back aperture of a 10x, 0.3 NA objective lens in an epi-illumination configuration. The emission pathway contains a 150 mm tube lens that focuses the light onto the linear sensor at the conjugate image plane. The linear sensor (ELiiXA+ 8k/4k) has three lateral binning modes which enables variable detection aperture widths between 5, 10, or 20 μm, which can be used to vary axial resolution. We have demonstrated redox-MHD-enabled light sheet microscopy in suspension of fluorescent polystyrene beads. This approach has potential as a high-throughput image cytometer with myriad cellular diagnostic applications.

Whillans Ice Stream Subglacial Access Research Drilling (WISSARD): Integrative Study of Marine Ice Sheet Stability and Subglacial Life Habitats (Invited)

NASA Astrophysics Data System (ADS)

Tulaczyk, S. M.; Anandakrishnan, S.; Behar, A. E.; Christner, B. C.; Fisher, A. T.; Fricker, H. A.; Holland, D. M.; Jacobel, R. W.; Mikucki, J.; Mitchell, A. C.; Powell, R. D.; Priscu, J. C.; Scherer, R. P.; Severinghaus, J. P.

2009-12-01

The WISSARD project is a large, NSF-funded, interdisciplinary initiative focused on scientific drilling, exploration, and investigation of Antarctic subglacial aquatic environments. The project consists of three interrelated components: (1) LISSARD - Lake and Ice Stream Subglacial Access Research Drilling, (2) RAGES - Robotic Access to Grounding-zones for Exploration and Science, and (3) GBASE - GeomicroBiology of Antarctic Subglacial Environments). A number of previous studies in West Antarctica highlighted the importance of understanding ice sheet interactions with water, either at the basal boundary where ice streams come in contact with active subglacial hydrologic and geological systems or at the marine margin where the ice sheet is exposed to forcing from the global ocean and sedimentation. Recent biological investigations of Antarctic subglacial environments show that they provide a significant habitat for life and source of bacterial carbon in a setting that was previously thought to be inhospitable. Subglacial microbial ecosystems also enhance biogeochemical weathering, mobilizing elements from long term geological storage. The overarching scientific objective of WISSARD is to examine the subglacial hydrological system of West Antarctica in glaciological, geological, microbiological, geochemical, and oceanographic contexts. Direct sampling will yield seminal information on these systems and test the overarching hypothesis that active hydrological systems connect various subglacial environments and exert major control on ice sheet dynamics, subglacial sediment transfer, geochemistry, metabolic and phylogenetic diversity, and biogeochemical transformations and geological records of ice sheet history. Technological advances during WISSARD will provide the US-science community with a capability to access and study sub-ice sheet environments. Developing this technological infrastructure will benefit the broader science community and it will be available for future use. Furthermore, these projects will pioneer an approach implementing recommendations from the National Research Council committee on Principles of Environmental Stewardship for the Exploration and Study of Subglacial Environments.

Automated drumlin shape and volume estimation using high resolution LiDAR imagery (Curvature Based Relief Separation): A test from the Wadena Drumlin Field, Minnesota

NASA Astrophysics Data System (ADS)

Yu, Peter; Eyles, Nick; Sookhan, Shane

2015-10-01

Resolving the origin(s) of drumlins and related megaridges in areas of megascale glacial lineations (MSGL) left by paleo-ice sheets is critical to understanding how ancient ice sheets interacted with their sediment beds. MSGL is now linked with fast-flowing ice streams but there is a broad range of erosional and depositional models. Further progress is reliant on constraining fluxes of subglacial sediment at the ice sheet base which in turn is dependent on morphological data such as landform shape and elongation and most importantly landform volume. Past practice in determining shape has employed a broad range of geomorphological methods from strictly visualisation techniques to more complex semi-automated and automated drumlin extraction methods. This paper reviews and builds on currently available visualisation, semi-automated and automated extraction methods and presents a new, Curvature Based Relief Separation (CBRS) technique; for drumlin mapping. This uses curvature analysis to generate a base level from which topography can be normalized and drumlin volume can be derived. This methodology is tested using a high resolution (3 m) LiDAR elevation dataset from the Wadena Drumlin Field, Minnesota, USA, which was constructed by the Wadena Lobe of the Laurentide Ice Sheet ca. 20,000 years ago and which as a whole contains 2000 drumlins across an area of 7500 km2. This analysis demonstrates that CBRS provides an objective and robust procedure for automated drumlin extraction. There is strong agreement with manually selected landforms but the method is also capable of resolving features that were not detectable manually thereby considerably expanding the known population of streamlined landforms. CBRS provides an effective automatic method for visualisation of large areas of the streamlined beds of former ice sheets and for modelling sediment fluxes below ice sheets.

Making a georeferenced mosaic of historical map series using constrained polynomial fit

NASA Astrophysics Data System (ADS)

Molnár, G.

2009-04-01

Present day GIS software packages make it possible to handle several hundreds of rasterised map sheets. For proper usage of such datasets we usually have two requirements: First these map sheets should be georeferenced, secondly these georeferenced maps should fit properly together, without overlap and short. Both requirements can be fulfilled easily, if the geodetic background for the map series is accurate, and the projection of the map series is known. In this case the individual map sheets should be georeferenced in the projected coordinate system of the map series. This means every individual map sheets are georeferenced using overprinted coordinate grid or image corner projected coordinates as ground control points (GCPs). If after this georeferencing procedure the map sheets do not fit together (for example because of using different projection for every map sheet, as it is in the case of Third Military Survey) a common projection can be chosen, and all the georeferenced maps should be transformed to this common projection using a map-to-map transformation. If the geodetic background is not so strong, ie. there are distortions inside the map sheets, a polynomial (linear quadratic or cubic) polynomial fit can be used for georeferencing the map sheets. Finding identical surface objects (as GCPs) on the historical map and on a present day cartographic map, let us to determine a transformation between raw image coordinates (x,y) and the projected coordinates (Easting, Northing, E,N). This means, for all the map sheets, several GCPs should be found, (for linear, quadratic of cubic transformations at least 3, 5 or 10 respectively) and every map sheets should be transformed to a present day coordinate system individually using these GCPs. The disadvantage of this method is that, after the transformation, the individual transformed map sheets not necessarily fit together properly any more. To overcome this problem neither the reverse order of procedure helps: if we make the mosaic first (eg. graphically) and we try the polynomial fit of this mosaic afterwards, neither using this can we reduce the error of internal inaccuracy of the map-sheets. We can overcome this problem by calculating the transformation parameters of polynomial fit with constrains (Mikhail, 1976). The constrain is that the common edge of two neighboring map-sheets should be transformed identically, ie. the right edge of the left image and the left edge of the right image should fit together after the transformation. This condition should fulfill for all the internal (not only the vertical, but also for the horizontal) edges of the mosaic. Constrains are expressed as a relationship between parameters: The parameters of the polynomial transformation should fulfill not only the least squares adjustment criteria but also the constrain: the transformed coordinates should be identical on the image edges. (With the example mentioned above, for image points of the rightmost column of the left image the transformed coordinates should be the same a for the image points of the leftmost column of the right image, and these transformed coordinates can depend on the line number image coordinate of the raster point.) The normal equation system can be calculated with Lagrange-multipliers. The resulting set of parameters for all map-sheets should be applied on the transformation of the images. This parameter set can not been directly applied in GIS software for the transformation. The simplest solution applying this parameters is ‘simulating' GCPs for every image, and applying these simulated GCPs for the georeferencing of the individual map sheets. This method is applied on a set of map-sheets of the First military Survey of the Habsburg Empire with acceptable results. Reference: Mikhail, E. M.: Observations and Least Squares. IEP—A Dun-Donnelley Publisher, New York, 1976. 497 pp.

An Effective Evolutionary Approach for Bicriteria Shortest Path Routing Problems

NASA Astrophysics Data System (ADS)

Lin, Lin; Gen, Mitsuo

Routing problem is one of the important research issues in communication network fields. In this paper, we consider a bicriteria shortest path routing (bSPR) model dedicated to calculating nondominated paths for (1) the minimum total cost and (2) the minimum transmission delay. To solve this bSPR problem, we propose a new multiobjective genetic algorithm (moGA): (1) an efficient chromosome representation using the priority-based encoding method; (2) a new operator of GA parameters auto-tuning, which is adaptively regulation of exploration and exploitation based on the change of the average fitness of parents and offspring which is occurred at each generation; and (3) an interactive adaptive-weight fitness assignment mechanism is implemented that assigns weights to each objective and combines the weighted objectives into a single objective function. Numerical experiments with various scales of network design problems show the effectiveness and the efficiency of our approach by comparing with the recent researches.

Minimizing the health and climate impacts of emissions from heavy-duty public transportation bus fleets through operational optimization.

PubMed

Gouge, Brian; Dowlatabadi, Hadi; Ries, Francis J

2013-04-16

In contrast to capital control strategies (i.e., investments in new technology), the potential of operational control strategies (e.g., vehicle scheduling optimization) to reduce the health and climate impacts of the emissions from public transportation bus fleets has not been widely considered. This case study demonstrates that heterogeneity in the emission levels of different bus technologies and the exposure potential of bus routes can be exploited though optimization (e.g., how vehicles are assigned to routes) to minimize these impacts as well as operating costs. The magnitude of the benefits of the optimization depend on the specific transit system and region. Health impacts were found to be particularly sensitive to different vehicle assignments and ranged from worst to best case assignment by more than a factor of 2, suggesting there is significant potential to reduce health impacts. Trade-offs between climate, health, and cost objectives were also found. Transit agencies that do not consider these objectives in an integrated framework and, for example, optimize for costs and/or climate impacts alone, risk inadvertently increasing health impacts by as much as 49%. Cost-benefit analysis was used to evaluate trade-offs between objectives, but large uncertainties make identifying an optimal solution challenging.

The effect of wind and moisture gradients on the arbitrary assignment of cloud motions to a vertical coordinate system in two Sesame cases

NASA Technical Reports Server (NTRS)

Peslen, C. A.; Koch, S. E.; Uccellini, L. W.

1984-01-01

Satellite-derived cloud motion 'wind' vectors (CMV) are increasingly used in mesoscale and in global analyses, and questions have been raised regarding the uncertainty of the level assignment for the CMV. One of two major problems in selecting a level for the CMV is related to uncertainties in assigning the motion vector to either the cloud top or base. The second problem is related to the inability to transfer the 'wind' derived from the CMV at individually specified heights to a standard coordinated surface. The present investigation has the objective to determine if the arbitrary level assignment represents a serious obstacle to the use of cloud motion wind vectors in the mesoscale analysis of a severe storm environment.

Force/torque and tactile sensors for sensor-based manipulator control

NASA Technical Reports Server (NTRS)

Vanbrussel, H.; Belieen, H.; Bao, Chao-Ying

1989-01-01

The autonomy of manipulators, in space and in industrial environments, can be dramatically enhanced by the use of force/torque and tactile sensors. The development and future use of a six-component force/torque sensor for the Hermes Robot Arm (HERA) Basic End-Effector (BEE) is discussed. Then a multifunctional gripper system based on tactile sensors is described. The basic transducing element of the sensor is a sheet of pressure-sensitive polymer. Tactile image processing algorithms for slip detection, object position estimation, and object recognition are described.

The "p"-Median Model as a Tool for Clustering Psychological Data

ERIC Educational Resources Information Center

Kohn, Hans-Friedrich; Steinley, Douglas; Brusco, Michael J.

2010-01-01

The "p"-median clustering model represents a combinatorial approach to partition data sets into disjoint, nonhierarchical groups. Object classes are constructed around "exemplars", that is, manifest objects in the data set, with the remaining instances assigned to their closest cluster centers. Effective, state-of-the-art implementations of…

Assessing Knowledge Change in Computer Science

ERIC Educational Resources Information Center

Nash, Jane Gradwohl; Bravaco, Ralph J.; Simonson, Shai

2006-01-01

The purpose of this study was to assess structural knowledge change across a two-week workshop designed to provide high-school teachers with training in Java and Object Oriented Programming. Both before and after the workshop, teachers assigned relatedness ratings to pairs of key concepts regarding Java and Object Oriented Programming. Their…

Object Interest in Autism Spectrum Disorder: A Treatment Comparison

ERIC Educational Resources Information Center

McDuffie, Andrea S.; Lieberman, Rebecca G.; Yoder, Paul J.

2012-01-01

A randomized control trial comparing two social communication treatments for children with autism spectrum disorder examined the effect of treatment on object interest. Thirty-two children, 18-60 months, were randomly assigned to the Picture Exchange Communication System (PECS) or Responsive Education and Prelinguistic Milieu Teaching (RPMT)…

Classification of Clinically Relevant Microorganisms in Non-Medical Environments

DTIC Science & Technology

2004-05-06

settings largely due to the rapidity of its evolutionary response to treatment. The first antibiotic-resistant strains of S . aureus were isolated only...studies have assigned isolates of the bacteria to known strains. The objectives of this study were to collect, isolate and characterize samples of S ...internal fragments of seven genes were obtained for 36 S . aureus isolates and assigned a unique allelic profile. These profiles, like fingerprints

40 CFR 471.02 - General definitions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... metal into a mold to produce an object of desired shape. (g) “Cladding” or “metal cladding” is the art... sheet, rod, or other long shapes by solidifying the metal while it is being poured through an open-ended mold. (j) “Degreasing” is the removal of oils and greases from the surface of the metal workpiece. This...

40 CFR 471.02 - General definitions.

Code of Federal Regulations, 2011 CFR

2011-07-01

... metal into a mold to produce an object of desired shape. (g) “Cladding” or “metal cladding” is the art... sheet, rod, or other long shapes by solidifying the metal while it is being poured through an open-ended mold. (j) “Degreasing” is the removal of oils and greases from the surface of the metal workpiece. This...

Aircraft Metal Skin Repair and Honeycomb Structure Repair; Sheet Metal Work 3: 9857.02.

ERIC Educational Resources Information Center

Dade County Public Schools, Miami, FL.

The course helps students determine types of repairs, compute repair sizes, and complete the repair through surface protection. Course content includes goals, specific objectives, protection of metals, repairs to metal skin, and honeycomb structure repair. A bibliography and post-test are appended. A prerequisite for this course is mastery of the…

Beyond the Point Charge: Equipotential Surfaces and Electric Fields of Various Charge Configurations

ERIC Educational Resources Information Center

Phillips, Jeffrey A.; Sanny, Jeff; Berube, David; Hoemke, Anatol

2017-01-01

A laboratory experiment often performed in an introductory electricity and magnetism course involves the mapping of equipotential lines on a conductive sheet between two objects at different potentials. In this article, we describe how we have expanded this experiment so that it can be used to illustrate the electrostatic properties of conductors.…

Single Sheet Agricultural Mechanics Plans.

ERIC Educational Resources Information Center

Schumacher, Leon, Ed.

This packet contains 25 single-page plans for agricultural mechanics projects. Each plan consists of a one-page set of drawings of the object to be made with a list of needed materials, a cut list, and step-by-step construction procedures on the back of the page. Plans for the following wood projects are included: bluebird house, lawn seat, dog…

Heating and Air Conditioning. Auto Mechanics Curriculum Guide Module 9. Instructor's Guide.

ERIC Educational Resources Information Center

Hevel, David

This unit of instruction is one of a series of modules in the Missouri Auto Mechanics Curriculum Guide. The module's format was developed for competency-based teaching and testing. The module contains 11 units, each of which contains the following components: a competency profile, objective sheets, references, notes to the instructor, lesson…

Electrical Experiments. VT-214-12-1. Part I. Electric Motor Control.

ERIC Educational Resources Information Center

Connecticut State Dept. of Education, Hartford. Div. of Vocational Education.

Designed for high school electronics students, this first document in a series of six electrical learning activity packages focuses on electric motor control. An introductory section gives the objective for the activities, an introduction, and an outline of the content. The remainder of the activity book is comprised of information sheets and job…

The Antartic Ice Borehole Probe

NASA Technical Reports Server (NTRS)

Behar, A.; Carsey, F.; Lane, A.; Engelhardt, H.

2000-01-01

The Antartic Ice Borehole Probe mission is a glaciological investigation, scheduled for November 2000-2001, that will place a probe in a hot-water drilled hole in the West Antartic ice sheet. The objectives of the probe are to observe ice-bed interactions with a downward looking camera, and ice inclusions and structure, including hypothesized ice accretion, with a side-looking camera.

Cecil Cereal's Supermarket Search. Teacher's Guide [and] Student Materials.

ERIC Educational Resources Information Center

Estes, Cynthia

The document presents objectives, teaching methods, activities, and work sheets for a unit on choosing breakfast cereal. The unit is intended to be used as an integral part of the fifth grade health program. Activities take place in a classroom learning center and can be completed in approximately four to six hours of classroom time. Objectives…

The Assignment of Scale to Object-Oriented Software Measures

NASA Technical Reports Server (NTRS)

Neal, Ralph D.; Weistroffer, H. Roland; Coppins, Richard J.

1997-01-01

In order to improve productivity (and quality), measurement of specific aspects of software has become imperative. As object oriented programming languages have become more widely used, metrics designed specifically for object-oriented software are required. Recently a large number of new metrics for object- oriented software has appeared in the literature. Unfortunately, many of these proposed metrics have not been validated to measure what they purport to measure. In this paper fifty (50) of these metrics are analyzed.

Towards an Artificial Space Object Taxonomy

NASA Astrophysics Data System (ADS)

Wilkins, M.; Schumacher, P.; Jah, M.; Pfeffer, A.

2013-09-01

Object recognition is the first step in positively identifying a resident space object (RSO), i.e. assigning an RSO to a category such as GPS satellite or space debris. Object identification is the process of deciding that two RSOs are in fact one and the same. Provided we have appropriately defined a satellite taxonomy that allows us to place a given RSO into a particular class of object without any ambiguity, one can assess the probability of assignment to a particular class by determining how well the object satisfies the unique criteria of belonging to that class. Ultimately, tree-based taxonomies delineate unique signatures by defining the minimum amount of information required to positively identify a RSO. Therefore, taxonomic trees can be used to depict hypotheses in a Bayesian object recognition and identification process. This work describes a new RSO taxonomy along with specific reasoning behind the choice of groupings. An alternative taxonomy was recently presented at the Sixth Conference on Space Debris in Darmstadt, Germany. [1] The best example of a taxonomy that enjoys almost universal scientific acceptance is the classical Linnaean biological taxonomy. A strength of Linnaean taxonomy is that it can be used to organize the different kinds of living organisms, simply and practically. Every species can be given a unique name. This uniqueness and stability are a result of the acceptance by biologists specializing in taxonomy, not merely of the binomial names themselves. Fundamentally, the taxonomy is governed by rules for the use of these names, and these are laid down in formal Nomenclature Codes. We seek to provide a similar formal nomenclature system for RSOs through a defined tree-based taxonomy structure. Each categorization, beginning with the most general or inclusive, at any level is called a taxon. Taxon names are defined by a type, which can be a specimen or a taxon of lower rank, and a diagnosis, a statement intended to supply characters that differentiate the taxon from others with which it is likely to be confused. Each taxon will have a set of uniquely distinguishing features that will allow one to place a given object into a specific group without any ambiguity. When a new object does not fall into a specific taxon that is already defined, the entire tree structure will need to be evaluated to determine if a new taxon should be created. Ultimately, an online learning process to facilitate tree growth would be desirable. One can assess the probability of assignment to a particular taxon by determining how well the object satisfies the unique criteria of belonging to that taxon. Therefore, we can use taxonomic trees in a Bayesian process to assign prior probabilities to each of our object recognition and identification hypotheses. We will show that this taxonomy is robust by demonstrating specific stressing classification examples. We will also demonstrate how to implement this taxonomy in Figaro, an open source probabilistic programming language.

Relationships between episodic memory performance prediction and sociodemographic variables among healthy older adults.

PubMed

de Oliveira, Glaucia Martins; Cachioni, Meire; Falcão, Deusivania; Batistoni, Samila; Lopes, Andrea; Guimarães, Vanessa; Lima-Silva, Thais Bento; Neri, Anita Liberalesso; Yassuda, Mônica Sanches

2015-01-01

Previous studies have suggested that performance prediction, an aspect of metamemory, may be associated with objective performance on memory tasks. The objective of the study was to describe memory prediction before performing an episodic memory task, in community-dwelling older adults, stratified by sex, age group and educational level. Additionally, the association between predicted and objective performance on a memory task was investigated. The study was based on data from 359 participants in the FIBRA study carried out at Ermelino Matarazzo, São Paulo. Memory prediction was assessed by posing the question: "If someone showed you a sheet with drawings of 10 pictures to observe for 30 seconds, how many pictures do you think you could remember without seeing the sheet?". Memory performance was assessed by the memorization of 10 black and white pictures from the Brief Cognitive Screening Battery (BCSB). No differences were found between men and women, nor for age group and educational level, in memory performance prediction before carrying out the memory task. There was a modest association (rho=0.11, p=0.041) between memory prediction and performance in immediate memory. On multivariate linear regression analyses, memory performance prediction was moderately significantly associated with immediate memory (p=0.061). In this study, sociodemographic variables did not influence memory prediction, which was only modestly associated with immediate memory on the Brief Cognitive Screening Battery (BCSB).

Investigating the Correlation Between Pharmacy Student Performance on the Health Science Reasoning Test and a Critical Thinking Assignment.

PubMed

Nornoo, Adwoa O; Jackson, Jonathan; Axtell, Samantha

2017-03-25

Objective. To determine whether there is a correlation between pharmacy students' scores on the Health Science Reasoning Test (HSRT) and their grade on a package insert assignment designed to assess critical thinking. Methods. The HSRT was administered to first-year pharmacy students during a critical-thinking course in the spring semester. In the same semester, a required package insert assignment was completed in a pharmacokinetics course. To determine whether there was a relationship between HSRT scores and grades on the assignment, a Spearman's rho correlation test was performed. Results. A very weak but significant positive correlation was found between students' grades on the assignment and their overall HSRT score (r=0.19, p <0.05), as well as deduction (a scale score of the HSRT; r=0.26, p <0.01). Conclusion. Based on a very weak but significant correlation to HSRT scores, this study demonstrated the potential of a package insert assignment to be used as one of the components to measure critical-thinking skills in pharmacy students.

Investigating the Correlation Between Pharmacy Student Performance on the Health Science Reasoning Test and a Critical Thinking Assignment

PubMed Central

Jackson, Jonathan; Axtell, Samantha

2017-01-01

Objective. To determine whether there is a correlation between pharmacy students’ scores on the Health Science Reasoning Test (HSRT) and their grade on a package insert assignment designed to assess critical thinking. Methods. The HSRT was administered to first-year pharmacy students during a critical-thinking course in the spring semester. In the same semester, a required package insert assignment was completed in a pharmacokinetics course. To determine whether there was a relationship between HSRT scores and grades on the assignment, a Spearman’s rho correlation test was performed. Results. A very weak but significant positive correlation was found between students’ grades on the assignment and their overall HSRT score (r=0.19, p<0.05), as well as deduction (a scale score of the HSRT; r=0.26, p<0.01). Conclusion. Based on a very weak but significant correlation to HSRT scores, this study demonstrated the potential of a package insert assignment to be used as one of the components to measure critical-thinking skills in pharmacy students. PMID:28381884

An Improved Hierarchical Genetic Algorithm for Sheet Cutting Scheduling with Process Constraints

PubMed Central

Rao, Yunqing; Qi, Dezhong; Li, Jinling

2013-01-01

For the first time, an improved hierarchical genetic algorithm for sheet cutting problem which involves n cutting patterns for m non-identical parallel machines with process constraints has been proposed in the integrated cutting stock model. The objective of the cutting scheduling problem is minimizing the weighted completed time. A mathematical model for this problem is presented, an improved hierarchical genetic algorithm (ant colony—hierarchical genetic algorithm) is developed for better solution, and a hierarchical coding method is used based on the characteristics of the problem. Furthermore, to speed up convergence rates and resolve local convergence issues, a kind of adaptive crossover probability and mutation probability is used in this algorithm. The computational result and comparison prove that the presented approach is quite effective for the considered problem. PMID:24489491

The balance sheet of benefits and harms of breast cancer population-based screening in Europe: outcome research, practice and future challenges.

PubMed

Broeders, Mireille; Paci, Eugenio

2015-11-01

Breast cancer screening programs are still object of harsh debate. In 2012, the Independent UK Panel reviewed the benefits and harms of mammography screening based on randomized trials and the EUROSCREEN Working Group reviewed European observational outcome studies. The conclusion was that screening programs should continue, while acknowledging that harms, such as the occurrence of false-positive results and overdiagnosis, can have a negative impact on a woman's life. Information on the balance sheet of the benefits and harms of breast cancer screening should help women and their physicians to make an informed choice. The future challenge for breast screening programs is to assess the feasibility, acceptability, effectiveness and impact of risk-based screening in order to maximize benefit-to-harm ratios.

An improved hierarchical genetic algorithm for sheet cutting scheduling with process constraints.

PubMed

Rao, Yunqing; Qi, Dezhong; Li, Jinling

2013-01-01

For the first time, an improved hierarchical genetic algorithm for sheet cutting problem which involves n cutting patterns for m non-identical parallel machines with process constraints has been proposed in the integrated cutting stock model. The objective of the cutting scheduling problem is minimizing the weighted completed time. A mathematical model for this problem is presented, an improved hierarchical genetic algorithm (ant colony--hierarchical genetic algorithm) is developed for better solution, and a hierarchical coding method is used based on the characteristics of the problem. Furthermore, to speed up convergence rates and resolve local convergence issues, a kind of adaptive crossover probability and mutation probability is used in this algorithm. The computational result and comparison prove that the presented approach is quite effective for the considered problem.

Development of Mathematics Learning Strategy Module, Based on Higher Order Thinking Skill (Hots) To Improve Mathematic Communication And Self Efficacy On Students Mathematics Department

NASA Astrophysics Data System (ADS)

Andriani, Ade; Dewi, Izwita; Halomoan, Budi

2018-03-01

In general, this research is conducted to improve the quality of lectures on mathematics learning strategy in Mathematics Department. The specific objective of this research is to develop learning instrument of mathematics learning strategy based on Higher Order Thinking Skill (HOTS) that can be used to improve mathematical communication and self efficacy of mathematics education students. The type of research is development research (Research & Development), where this research aims to develop a new product or improve the product that has been made. This development research refers to the four-D Model, which consists of four stages: defining, designing, developing, and disseminating. The instrument of this research is the validation sheet and the student response sheet of the instrument.

Scribbling on the blank sheet: Eddington's structuralist conception of objects

NASA Astrophysics Data System (ADS)

French, Steven

Although Eddington's philosophy of physics has been subjected to critical re-evaluation in recent years, neither the exact nature of his structuralist views nor his response to criticism by the likes of Braithwaite have been made clear. In this paper I trace, in particular, the incorporation into Eddington's structuralism of the non-classical indistinguishability of quantum objects. His metaphysical view of such objects as the product of group-theoretical analysis is crucial for understanding his response to Braithwaite's criticisms of the whole structuralist endeavor. These criticisms closely resemble more recent attacks on structural realism in the philosophy of science. I conclude with a brief comparison between these more modern forms of structuralism and Eddington's.

Software Techniques for Non-Von Neumann Architectures

DTIC Science & Technology

1990-01-01

Commtopo programmable Benes net.; hypercubic lattice for QCD Control CENTRALIZED Assign STATIC Memory :SHARED Synch UNIVERSAL Max-cpu 566 Proessor...boards (each = 4 floating point units, 2 multipliers) Cpu-size 32-bit floating point chips Perform 11.4 Gflops Market quantum chromodynamics ( QCD ...functions there should exist a capability to define hierarchies and lattices of complex objects. A complex object can be made up of a set of simple objects

A Pilot Study of Simple Interventions to Improve Informed Consent in Clinical Research: Feasibility, Approach, and Results

PubMed Central

Kass, Nancy; Taylor, Holly; Ali, Joseph; Hallez, Kristina; Chaisson, Lelia

2014-01-01

Background Informed consent is intended to ensure that individuals understand the purpose, risks, and benefits of research studies, and then can decide, voluntarily, whether to enroll. However, research suggests that consent procedures do not always lead to adequate participant understanding and may be longer and more complex than necessary. Studies also suggest some consent interventions, including enhanced consent forms and extended discussions with patients, increase understanding, yet methodologic challenges have been raised in studying consent in actual trial settings. This study aimed to examine the feasibility of testing two consent interventions in actual studies and also to measure effectiveness of interventions in improving understanding of trials. Methods Participants enrolling in any of eight ongoing clinical trials (“collaborating studies”) were, for the purposes of this study, sequentially assigned to one of three study arms involving different informed consent procedures (one control and two intervention). Control participants received standard consent form and processes. Participants in the 1st intervention arm received a bulleted fact-sheet providing simple summaries of all study components in addition to the standard consent form. Participants in the 2nd intervention arm received the bulleted fact-sheet and standard consent materials and then also engaged with a member of the collaborating study staff in a feedback Q&A session. Following consent procedures, we administered closed and open ended questions to assess patient understanding and we assessed literacy level. Descriptive statistics, Wilcoxon-Mann-Whitney and Kruskal-Wallis tests were generated to assess correlations; regression analysis determined predictors of patient understanding. Results 144 participants enrolled. Using regression analysis participants receiving the 2nd intervention, which included a standard consent form, bulleted fact sheet and structured question and answer session with a study staff member, had open-ended question scores that were 7.6 percentage points higher (p=.02) than participants who received the control arm (standard consent only), although unadjusted comparisons did not reach statistical significance. Eleven clinical trial investigators agreed to participate and 8 trials provided sufficient data to be included, thereby demonstrating feasibility of consent research in actual settings. Conclusions Our study supports the hypothesis that patients receiving both bulleted fact sheets and a question and answer session have higher understanding compared to patients receiving standard consent form and procedures alone. Fact sheets and short structured dialog are quick to administer and easy to replicate across studies and should be tested in larger samples for effectiveness. PMID:25475879

A randomized controlled trial of contingency management for psycho-stimulant use in community mental health outpatients with co-occurring serious mental illness

PubMed Central

McDonell, Michael G.; Srebnik, Debra; Angelo, Frank; McPherson, Sterling; Lowe, Jessica M.; Sugar, Andrea; Short, Robert A.; Roll, John M.; Ries, Richard K.

2014-01-01

Objective The primary objective of this study was to determine if contingency management was associated with increased stimulant drug abstinence in community mental health outpatients with serious mental illness and stimulant dependence. Secondary objectives were to determine if contingency management was associated with reductions in use of other substances, psychiatric symptoms, HIV-risk behavior, and inpatient service utilization. Method A randomized controlled design compared outcomes of 176 outpatients with serious mental illness and stimulant dependence. Participants were randomized to three months of contingency management for stimulant abstinence plus treatment-as-usual or treatment-as-usual with reinforcement for study participation only. Urine drug tests, self-report, clinician-report, and service utilization outcomes were assessed during three-month treatment and three-month follow-up periods. Results While participants in the contingency management condition were less likely to complete the treatment period (n=38; 42%) than those assigned to the control condition (n=55; 65%), X2(1)=9.8, p=0.02; those assigned to the contingency management condition were 2.4 (CI=1.9-3.0) times more likely to submit a stimulant-negative urine test during treatment. Participants assigned to contingency management experienced significantly lower levels of alcohol use, injection drug use, psychiatric symptoms, and were five times less likely than those assigned to the control condition to be admitted for psychiatric hospitalization, X2(1)=5.4, p=0.02. Contingency management participants reported significantly fewer days of stimulant drug use, relative to controls during the three-month follow-up. Conclusions When added to treatment-as-usual, contingency management is associated with large reductions in stimulant, injection drug, and alcohol use. Reductions in psychiatric symptoms and hospitalizations were important secondary benefits. PMID:23138961

Learning by Doing--Teaching Systematic Review Methods in 8 Weeks

ERIC Educational Resources Information Center

Li, Tianjing; Saldanha, Ian J.; Vedula, S. Swaroop; Yu, Tsung; Rosman, Lori; Twose, Claire; Goodman, Steven N.; Dickersin, Kay

2014-01-01

Objective: The objective of this paper is to describe the course "Systematic Reviews and Meta-analysis" at the Johns Hopkins Bloomberg School of Public Health. Methods: A distinct feature of our course is a group project in which students, assigned to multi-disciplinary groups, conduct a systematic review. In-class sessions comprise…

Preservice Elementary Teachers Increase Descriptive Science Vocabulary by Making Descriptive Adjective Object Boxes

ERIC Educational Resources Information Center

Rule, Audrey C.; Crisafulli, Sherry; DeCare, Heather; DeLeo, Tonya; Eastman, Keri; Farrell, Liz; Geblein, Jennifer; Gioia, Chelsea; Joyce, Ashley; Killian, Kali; Knoop, Kelly; LaRocca, Alison; Meyer, Katie; Miller, Julianne; Roth, Vicki; Throo, Julie; Van Arsdale, Jim; Walker, Malissa

2007-01-01

Descriptive vocabulary is needed for communication and mental processing of science observations. Elementary preservice teachers in a science methods class at a mid-sized public college in central New York State increased their descriptive vocabularies through a course assignment of making a descriptive adjective object box. This teaching material…

A New Zero-Inflated Negative Binomial Methodology for Latent Category Identification

ERIC Educational Resources Information Center

Blanchard, Simon J.; DeSarbo, Wayne S.

2013-01-01

We introduce a new statistical procedure for the identification of unobserved categories that vary between individuals and in which objects may span multiple categories. This procedure can be used to analyze data from a proposed sorting task in which individuals may simultaneously assign objects to multiple piles. The results of a synthetic…

Violence and Objectivity in Psychology.

ERIC Educational Resources Information Center

Kenny, Wade

The subject and the object are more strategically assigned than some might readily assume, both as people speak and as they live them. Subjectivity is associated with doing, hence responsibility, and therefore it noticeably slides in matters of credit and blame, with issues like Newton's or LaPlace's discovery. In scientific papers the subject has…

A Multidimensional Scaling Approach to Developmental Dimensions in Object Permanence and Tracking Stimuli.

ERIC Educational Resources Information Center

Townes-Rosenwein, Linda

This paper discusses a longitudinal, exploratory study of developmental dimensions related to object permanence theory and explains how multidimensional scaling techniques can be used to identify developmental dimensions. Eighty infants, randomly assigned to one of four experimental groups and one of four counterbalanced orders of stimuli, were…

Order-Constrained Solutions in K-Means Clustering: Even Better than Being Globally Optimal

ERIC Educational Resources Information Center

Steinley, Douglas; Hubert, Lawrence

2008-01-01

This paper proposes an order-constrained K-means cluster analysis strategy, and implements that strategy through an auxiliary quadratic assignment optimization heuristic that identifies an initial object order. A subsequent dynamic programming recursion is applied to optimally subdivide the object set subject to the order constraint. We show that…

Static assignment of complex stochastic tasks using stochastic majorization

NASA Technical Reports Server (NTRS)

Nicol, David; Simha, Rahul; Towsley, Don

1992-01-01

We consider the problem of statically assigning many tasks to a (smaller) system of homogeneous processors, where a task's structure is modeled as a branching process, and all tasks are assumed to have identical behavior. We show how the theory of majorization can be used to obtain a partial order among possible task assignments. Our results show that if the vector of numbers of tasks assigned to each processor under one mapping is majorized by that of another mapping, then the former mapping is better than the latter with respect to a large number of objective functions. In particular, we show how measurements of finishing time, resource utilization, and reliability are all captured by the theory. We also show how the theory may be applied to the problem of partitioning a pool of processors for distribution among parallelizable tasks.

Unravelling source regions of ice rafted debris within three NE Atlantic marine sediment cores during the deglacial interval: a multi-proxy approach

NASA Astrophysics Data System (ADS)

Small, David; Hibbert, Fiona; Austin, Bill

2010-05-01

Ice-rafted debris (IRD) within marine sediments of the North Atlantic provide an important archive of glacial activity on adjacent landmasses and attest to the activity of multiple calving ice margins during the last glacial cycle. IRD records therefore provide a means to reconstruct ice sheet dynamics and their interaction with the climate system, providing evidence of both the source of the ice and the location of melting (e.g. Ruddiman, 1977; Bond and Lotti, 1995). The complex interaction of the circum-Atlantic ice sheets and limitations of individual techniques often hinders firm source designations (i.e. IRD may be derived from multiple sources which cannot be differentiated by, for example, visual characterisation). Initial work identified diagnostic grain types that could be attributed to source areas of palaeo ice-sheets (eg: Bond & Lotti 1995) however, for the BIS, "diagnostic" basalt may be derived from sources to the east and west of the cores (Hibbert et al 2009, Scourse et al 2009). We therefore, utilise a multi-proxy approach to investigate the deglacial dynamics of the last British Ice Sheet (BIS) using inter alia lithic characterisation, fluxes of IRD to the core sites, magnetic susceptibility and a magnetic un-mixing model. A novel application of major element geochemistry of garnets contained within ice-rafted debris of the three high resolution marine sediment cores is presented. Garnets can be used to infer provenance (e.g. Oliver 2001) as major element composition may be assigned to specific metamorphic terranes. The IRD present within these cores is believed to be predominantly sourced from the BIS (cf: Knutz et al 2001, Hibbert et al 2009). This assertion is tested through multiple analytical techniques used and replication of records across the Hebridean shelf into the deep ocean. References • Bond, G.C. & Lotti, R., 1995. Iceberg discharges into the North Atlantic on millennial timescales during the last glaciation. Science 267. pp. 1005-1010. • Hibbert, F.D., Austin, W.E.N., Leng, M.J. and Gatliff, R.W., 2009. British Ice Sheet Dynamics inferred from North Atlantice ice-rafted debris records spanning the last 175,000 years. Journal of Quaternary Science. ISSN 0267-8179. • Knutz, P.C., Austin, W.E.N. and Jones, E.J.W., 2001. Millenial-scale depositional cycles related to British Ice Sheet variability and North Atlantic paleocirculation since 45kyr B.P., Barra Fan, U.K. margin. Paleoceanography 16. pp.53-64. • Oliver, G.J.H., 2001. Reconstruction of the Grampian episode in Scotland: it's place in the Caledonian Orogeny. Tectonphysics 332. pp.23-49. • Ruddiman, W.F., 1977. Late Quaternary deposition of ice-rafted sand in the sub-polar North Atlantic (lat 40° to 65°). Geological Society of America Bulletin 88. pp.1813-1821. • Scourse, J.D., Haapaniemi, A.I., Colmenero-Hidalgo, E., Peck, V.L., Hall, I.R., Austin, W.E.N., Knutz, P.C. and Zahn, R., 2009. Growth, dynamics and deglaciation of the last British-Irish Ice Sheet: the deep-sea ice-rafted detritus record. Quaternary Science Reviews 28. pp.3066-3084.

MGmapper: Reference based mapping and taxonomy annotation of metagenomics sequence reads

PubMed Central

Lukjancenko, Oksana; Thomsen, Martin Christen Frølund; Maddalena Sperotto, Maria; Lund, Ole; Møller Aarestrup, Frank; Sicheritz-Pontén, Thomas

2017-01-01

An increasing amount of species and gene identification studies rely on the use of next generation sequence analysis of either single isolate or metagenomics samples. Several methods are available to perform taxonomic annotations and a previous metagenomics benchmark study has shown that a vast number of false positive species annotations are a problem unless thresholds or post-processing are applied to differentiate between correct and false annotations. MGmapper is a package to process raw next generation sequence data and perform reference based sequence assignment, followed by a post-processing analysis to produce reliable taxonomy annotation at species and strain level resolution. An in-vitro bacterial mock community sample comprised of 8 genuses, 11 species and 12 strains was previously used to benchmark metagenomics classification methods. After applying a post-processing filter, we obtained 100% correct taxonomy assignments at species and genus level. A sensitivity and precision at 75% was obtained for strain level annotations. A comparison between MGmapper and Kraken at species level, shows MGmapper assigns taxonomy at species level using 84.8% of the sequence reads, compared to 70.5% for Kraken and both methods identified all species with no false positives. Extensive read count statistics are provided in plain text and excel sheets for both rejected and accepted taxonomy annotations. The use of custom databases is possible for the command-line version of MGmapper, and the complete pipeline is freely available as a bitbucked package (https://bitbucket.org/genomicepidemiology/mgmapper). A web-version (https://cge.cbs.dtu.dk/services/MGmapper) provides the basic functionality for analysis of small fastq datasets. PMID:28467460

MGmapper: Reference based mapping and taxonomy annotation of metagenomics sequence reads.

PubMed

Petersen, Thomas Nordahl; Lukjancenko, Oksana; Thomsen, Martin Christen Frølund; Maddalena Sperotto, Maria; Lund, Ole; Møller Aarestrup, Frank; Sicheritz-Pontén, Thomas

2017-01-01

An increasing amount of species and gene identification studies rely on the use of next generation sequence analysis of either single isolate or metagenomics samples. Several methods are available to perform taxonomic annotations and a previous metagenomics benchmark study has shown that a vast number of false positive species annotations are a problem unless thresholds or post-processing are applied to differentiate between correct and false annotations. MGmapper is a package to process raw next generation sequence data and perform reference based sequence assignment, followed by a post-processing analysis to produce reliable taxonomy annotation at species and strain level resolution. An in-vitro bacterial mock community sample comprised of 8 genuses, 11 species and 12 strains was previously used to benchmark metagenomics classification methods. After applying a post-processing filter, we obtained 100% correct taxonomy assignments at species and genus level. A sensitivity and precision at 75% was obtained for strain level annotations. A comparison between MGmapper and Kraken at species level, shows MGmapper assigns taxonomy at species level using 84.8% of the sequence reads, compared to 70.5% for Kraken and both methods identified all species with no false positives. Extensive read count statistics are provided in plain text and excel sheets for both rejected and accepted taxonomy annotations. The use of custom databases is possible for the command-line version of MGmapper, and the complete pipeline is freely available as a bitbucked package (https://bitbucket.org/genomicepidemiology/mgmapper). A web-version (https://cge.cbs.dtu.dk/services/MGmapper) provides the basic functionality for analysis of small fastq datasets.

Evaluation of the appropriateness and outcome of in-hospital telemetry monitoring.

PubMed

Fålun, Nina; Nordrehaug, Jan Erik; Hoff, Per Ivar; Langørgen, Jørund; Moons, Philip; Norekvål, Tone M

2013-10-15

The American Heart Association classifies monitored patients into 3 categories. The aims of this study were to (1) investigate how patients are assigned according to the American Heart Association classification, (2) determine the number and type of arrhythmic events experienced by these patients, and (3) describe subsequent changes in management. A prospective observational study design was used. All patients assigned to telemetry during a 3-month period were consecutively enrolled in our study. Data were collected 24/7. Only arrhythmias that might require a change in management were recorded. Monitor watchers at the central monitoring station completed a standard data sheet assessing 64 variables. These data, as well as medical records, were reviewed by the investigator. Overall, 1,194 patients were included. Eighteen percent of the patients were assigned to American Heart Association class I (monitoring indicated), 71% to class II (monitoring may be of benefit), and 11% to class III (monitoring not indicated). The overall arrhythmia event rate was 33%. Forty-three percent of class I patients, 28% of class II patients, and 47% of class III patients experienced arrhythmia events. Change in management occurred in 25% of class I patients, 14% of class II patients, and 29% of class III patients. Although the number of class III indications should have been reduced, nearly 1/2 of class III patients experienced arrhythmia events and 1/3 of them received management changes. This outcome challenges existing guidelines. In conclusion, most patients in this study were monitored appropriately, according to class I and II indications. Copyright © 2013 Elsevier Inc. All rights reserved.

Ant colony optimization for solving university facility layout problem

NASA Astrophysics Data System (ADS)

Mohd Jani, Nurul Hafiza; Mohd Radzi, Nor Haizan; Ngadiman, Mohd Salihin

2013-04-01

Quadratic Assignment Problems (QAP) is classified as the NP hard problem. It has been used to model a lot of problem in several areas such as operational research, combinatorial data analysis and also parallel and distributed computing, optimization problem such as graph portioning and Travel Salesman Problem (TSP). In the literature, researcher use exact algorithm, heuristics algorithm and metaheuristic approaches to solve QAP problem. QAP is largely applied in facility layout problem (FLP). In this paper we used QAP to model university facility layout problem. There are 8 facilities that need to be assigned to 8 locations. Hence we have modeled a QAP problem with n ≤ 10 and developed an Ant Colony Optimization (ACO) algorithm to solve the university facility layout problem. The objective is to assign n facilities to n locations such that the minimum product of flows and distances is obtained. Flow is the movement from one to another facility, whereas distance is the distance between one locations of a facility to other facilities locations. The objective of the QAP is to obtain minimum total walking (flow) of lecturers from one destination to another (distance).

Nuclear Data Sheets for A = 70

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gürdal, G.; McCutchan, E.A.

2016-09-15

Spectroscopic data for all nuclei with mass number A = 70 have been evaluated, and the corresponding level schemes from radioactive decay and reaction studies are presented. Since the previous evaluation, the half-life of {sup 70}Mn has been measured and excited states in {sup 70}Fe observed for the first time. Excited states in {sup 70}Ni have been more extensively studied while Coulomb excitation and collinear laser spectroscopy measurements in {sup 70}Cu have allowed for firm Jπ assignments. Despite new measurements, there remain some discrepancies in half-lives of low lying states in {sup 70}Zn. New measurements have extended the knowledge ofmore » high-spin band structures in {sup 70}Ge and {sup 70}As. This evaluation supersedes the prior A = 70 evaluation of 2004Tu09.« less

Nuclear Data Sheets for A=241

DOE PAGES

Nesaraja, Caroline D.

2015-11-27

This paper presents available information pertaining to the nuclear structure of ground and excited states for all known nuclei with mass numbers A=24, which have been compiled and evaluated. The adopted level and decay schemes, as well as the detailed nuclear properties and configuration assignments based on experimental data are presented for these nuclides. When there are insufficient data, expected values from systematics of nuclear properties or/and theoretical calculations are quoted. Unexpected or discrepant experimental results are also noted. A summary and compilation of the discovery of various isotopes in this mass region is given in 2013Fr02 ( 241Np, 241Pu,more » 241Am, 241Cm, 241Bk, and 241Cf), 2011Me01 (241Es), and 2013Th02 ( 241Fm).« less

QAPgrid: A Two Level QAP-Based Approach for Large-Scale Data Analysis and Visualization

PubMed Central

Inostroza-Ponta, Mario; Berretta, Regina; Moscato, Pablo

2011-01-01

Background The visualization of large volumes of data is a computationally challenging task that often promises rewarding new insights. There is great potential in the application of new algorithms and models from combinatorial optimisation. Datasets often contain “hidden regularities” and a combined identification and visualization method should reveal these structures and present them in a way that helps analysis. While several methodologies exist, including those that use non-linear optimization algorithms, severe limitations exist even when working with only a few hundred objects. Methodology/Principal Findings We present a new data visualization approach (QAPgrid) that reveals patterns of similarities and differences in large datasets of objects for which a similarity measure can be computed. Objects are assigned to positions on an underlying square grid in a two-dimensional space. We use the Quadratic Assignment Problem (QAP) as a mathematical model to provide an objective function for assignment of objects to positions on the grid. We employ a Memetic Algorithm (a powerful metaheuristic) to tackle the large instances of this NP-hard combinatorial optimization problem, and we show its performance on the visualization of real data sets. Conclusions/Significance Overall, the results show that QAPgrid algorithm is able to produce a layout that represents the relationships between objects in the data set. Furthermore, it also represents the relationships between clusters that are feed into the algorithm. We apply the QAPgrid on the 84 Indo-European languages instance, producing a near-optimal layout. Next, we produce a layout of 470 world universities with an observed high degree of correlation with the score used by the Academic Ranking of World Universities compiled in the The Shanghai Jiao Tong University Academic Ranking of World Universities without the need of an ad hoc weighting of attributes. Finally, our Gene Ontology-based study on Saccharomyces cerevisiae fully demonstrates the scalability and precision of our method as a novel alternative tool for functional genomics. PMID:21267077

QAPgrid: a two level QAP-based approach for large-scale data analysis and visualization.

PubMed

Inostroza-Ponta, Mario; Berretta, Regina; Moscato, Pablo

2011-01-18

The visualization of large volumes of data is a computationally challenging task that often promises rewarding new insights. There is great potential in the application of new algorithms and models from combinatorial optimisation. Datasets often contain "hidden regularities" and a combined identification and visualization method should reveal these structures and present them in a way that helps analysis. While several methodologies exist, including those that use non-linear optimization algorithms, severe limitations exist even when working with only a few hundred objects. We present a new data visualization approach (QAPgrid) that reveals patterns of similarities and differences in large datasets of objects for which a similarity measure can be computed. Objects are assigned to positions on an underlying square grid in a two-dimensional space. We use the Quadratic Assignment Problem (QAP) as a mathematical model to provide an objective function for assignment of objects to positions on the grid. We employ a Memetic Algorithm (a powerful metaheuristic) to tackle the large instances of this NP-hard combinatorial optimization problem, and we show its performance on the visualization of real data sets. Overall, the results show that QAPgrid algorithm is able to produce a layout that represents the relationships between objects in the data set. Furthermore, it also represents the relationships between clusters that are feed into the algorithm. We apply the QAPgrid on the 84 Indo-European languages instance, producing a near-optimal layout. Next, we produce a layout of 470 world universities with an observed high degree of correlation with the score used by the Academic Ranking of World Universities compiled in the The Shanghai Jiao Tong University Academic Ranking of World Universities without the need of an ad hoc weighting of attributes. Finally, our Gene Ontology-based study on Saccharomyces cerevisiae fully demonstrates the scalability and precision of our method as a novel alternative tool for functional genomics.

Force Protection Basing: Fact Sheet

DTIC Science & Technology

2017-11-29

experimentation and demonstrations during FY15. The FY16 demonstration assessed the capability to protect a contingency base within objective metrics for time and...protection technologies 2 had baseline capabilities assessed in early FY15; followed by integration experimentation and demonstrations during FY15...included DOTMLPF integration and the finalization of CONOPs and TTPs for basing protection using experimental data. CONOPs/TTPs for the phases of

Chapter 8:Properties of red maple laminated veneer lumber

Treesearch

Robert J. Ross; Xiping Wang; Brian K. Brashaw; John W. Forsman; John R. Erickson

2005-01-01

The purpose of the work reported in this chapter was to examine the flexural properties of LVL manufactured from ultrasonically rated red maple veneer sheets. The specific objectives were: 1. to determine the flatwise and edgewise bending properties of ½ inch-(1.3-cm-) thick red maple LVL billets, and 2. to examine the relationship between nondestructive parameters of...

77 FR 40897 - Notice of Intent to Repatriate Cultural Items: Gregg County Historical Museum, Longview, TX

Federal Register 2010, 2011, 2012, 2013, 2014

2012-07-11

... and thereafter, six unassociated funerary objects were removed from burials at the C.D. Marsh site... piece of sheet brass, and 1 brass musket butt plate. The Millsey Williamson site dates to A.D. 1650-1800..., the Late-Historic Caddo period. Sometime between the mid-1950s and the mid-1960s, six unassociated...

Let's Go Exploring. Nutrition Comes Alive. Level 1. Nutrition Educator's Guide and Work Sheets, Letters to Parents, Recipes. Revised Edition.

ERIC Educational Resources Information Center

Farrell, Tracy J.

This guide provides a nutrition education program for elementary school students that spans kindergarten through Grade 3 as well as providing activities for specific levels. Nutrition education objectives are stated for each grade level: (1) kindergarten--students will become familiar with and motivated to eat a variety of foods; (2) grade…

Skills for Health Care Assistants. Supplemental Units for Health Care and Nurse Assistants Programs. Student Guide. Revised.

ERIC Educational Resources Information Center

Missouri Univ., Columbia. Instructional Materials Lab.

This guide contains 13 units to be used as a supplement in nurse assistant and health services courses. The units are self-paced and contain simplified line drawings, controlled text, vocabulary development, and mathematics practice exercises. Units consist of objectives, an introduction, a content outline, steps of a procedure, skill sheets,…

Skills for Health Care Assistants Vol. II. Supplemental Units for Health Care and Nurse Assistants Programs. Student Guide. Instructor Key. Revised.

ERIC Educational Resources Information Center

Missouri Univ., Columbia. Instructional Materials Lab.

This student guide for courses for health care assistants and nurse assistants contains 16 self-paced units with simplified line drawings, controlled text, vocabulary development, and mathematics practice exercises. Units consist of the following: objectives, introduction to the unit, content outline, steps of the procedure, skill sheets, written…

Qualification of an Acceptable Alternative to Halon 1211 DOD Flightline Extinguishers

DTIC Science & Technology

2008-09-01

Minimum Performance Standard MSDS Material Safety Data Sheet NATO North Atlantic Treaty Organization NAWCAD Naval Air Warfare Center Aircraft...included chronic and acute occupational exposure limits and cardiotoxicity. Alternatives that were carcinogens or that had any adverse developmental...gear to fight the fires Does not exceed pain threshold for exposed skin Each unit tested met this performance objective 2. Firefighting

Fuels planning: science synthesis and integration; economic uses fact sheet 08: prescribed fire costs

Treesearch

Rocky Mountain Research Station USDA Forest Service

2004-01-01

Although the use of prescribed fire as a management tool is widespread, there is great variability and uncertainty in the treatment costs. Given specific site variables and management objectives, how much will it cost to use prescribed fire? This paper describes the FASTRACS database, a tool that has been developed to aid managers in addressing this question.

Flow pathways and sediment trapping in a field-scale vegetative filter

Treesearch

M. J. Helmers; D. E. Eisenhauer; Mike G. Dosskey; T. G. Franti; J. M. Brothers; M. C. McCullough

2005-01-01

Vegetative filters (VF) are a best management practive installed in many areas to control sediment movement to water bodies. It is commonly assumed that runoff proceeds perpendicularly across a VF as sheet flow. However, there is little research information on natural pathways of water movement and performance of field-scale VF. The objectives of this study were: (1)...