Sample records for obtain hazard ratios

  1. The Average Hazard Ratio - A Good Effect Measure for Time-to-event Endpoints when the Proportional Hazard Assumption is Violated?

    PubMed

    Rauch, Geraldine; Brannath, Werner; Brückner, Matthias; Kieser, Meinhard

    2018-05-01

    In many clinical trial applications, the endpoint of interest corresponds to a time-to-event endpoint. In this case, group differences are usually expressed by the hazard ratio. Group differences are commonly assessed by the logrank test, which is optimal under the proportional hazard assumption. However, there are many situations in which this assumption is violated. Especially in applications were a full population and several subgroups or a composite time-to-first-event endpoint and several components are considered, the proportional hazard assumption usually does not simultaneously hold true for all test problems under investigation. As an alternative effect measure, Kalbfleisch and Prentice proposed the so-called 'average hazard ratio'. The average hazard ratio is based on a flexible weighting function to modify the influence of time and has a meaningful interpretation even in the case of non-proportional hazards. Despite this favorable property, it is hardly ever used in practice, whereas the standard hazard ratio is commonly reported in clinical trials regardless of whether the proportional hazard assumption holds true or not. There exist two main approaches to construct corresponding estimators and tests for the average hazard ratio where the first relies on weighted Cox regression and the second on a simple plug-in estimator. The aim of this work is to give a systematic comparison of these two approaches and the standard logrank test for different time-toevent settings with proportional and nonproportional hazards and to illustrate the pros and cons in application. We conduct a systematic comparative study based on Monte-Carlo simulations and by a real clinical trial example. Our results suggest that the properties of the average hazard ratio depend on the underlying weighting function. The two approaches to construct estimators and related tests show very similar performance for adequately chosen weights. In general, the average hazard ratio defines a

  2. A balanced hazard ratio for risk group evaluation from survival data.

    PubMed

    Branders, Samuel; Dupont, Pierre

    2015-07-30

    Common clinical studies assess the quality of prognostic factors, such as gene expression signatures, clinical variables or environmental factors, and cluster patients into various risk groups. Typical examples include cancer clinical trials where patients are clustered into high or low risk groups. Whenever applied to survival data analysis, such groups are intended to represent patients with similar survival odds and to select the most appropriate therapy accordingly. The relevance of such risk groups, and of the related prognostic factors, is typically assessed through the computation of a hazard ratio. We first stress three limitations of assessing risk groups through the hazard ratio: (1) it may promote the definition of arbitrarily unbalanced risk groups; (2) an apparently optimal group hazard ratio can be largely inconsistent with the p-value commonly associated to it; and (3) some marginal changes between risk group proportions may lead to highly different hazard ratio values. Those issues could lead to inappropriate comparisons between various prognostic factors. Next, we propose the balanced hazard ratio to solve those issues. This new performance metric keeps an intuitive interpretation and is as simple to compute. We also show how the balanced hazard ratio leads to a natural cut-off choice to define risk groups from continuous risk scores. The proposed methodology is validated through controlled experiments for which a prescribed cut-off value is defined by design. Further results are also reported on several cancer prognosis studies, and the proposed methodology could be applied more generally to assess the quality of any prognostic markers. Copyright © 2015 John Wiley & Sons, Ltd.

  3. On the Interpretation of the Hazard Ratio and Communication of Survival Benefit.

    PubMed

    Sashegyi, Andreas; Ferry, David

    2017-04-01

    This brief communication will clarify the difference between a relative hazard and a relative risk. We highlight the importance of this difference, and demonstrate in practical terms that 1 minus the hazard ratio should not be interpreted as a risk reduction in the commonly understood sense of the term. This article aims to provide a better understanding of the type of risk reduction that a hazard ratio implies, thereby clarifying the intent in the communication among practitioners and researchers and establishing an accurate and realistic foundation for communicating with patients. The Oncologist 2017;22:484-486. © AlphaMed Press 2017.

  4. 25 CFR 170.905 - How can tribes obtain training in handling hazardous material?

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 25 Indians 1 2011-04-01 2011-04-01 false How can tribes obtain training in handling hazardous... Transportation § 170.905 How can tribes obtain training in handling hazardous material? (a) Tribes cannot use IRR Program funds to train personnel to handle radioactive and hazardous material. (b) Tribes can seek...

  5. Hazard ratio estimation and inference in clinical trials with many tied event times.

    PubMed

    Mehrotra, Devan V; Zhang, Yiwei

    2018-06-13

    The medical literature contains numerous examples of randomized clinical trials with time-to-event endpoints in which large numbers of events accrued over relatively short follow-up periods, resulting in many tied event times. A generally common feature across such examples was that the logrank test was used for hypothesis testing and the Cox proportional hazards model was used for hazard ratio estimation. We caution that this common practice is particularly risky in the setting of many tied event times for two reasons. First, the estimator of the hazard ratio can be severely biased if the Breslow tie-handling approximation for the Cox model (the default in SAS and Stata software) is used. Second, the 95% confidence interval for the hazard ratio can include one even when the corresponding logrank test p-value is less than 0.05. To help establish a better practice, with applicability for both superiority and noninferiority trials, we use theory and simulations to contrast Wald and score tests based on well-known tie-handling approximations for the Cox model. Our recommendation is to report the Wald test p-value and corresponding confidence interval based on the Efron approximation. The recommended test is essentially as powerful as the logrank test, the accompanying point and interval estimates of the hazard ratio have excellent statistical properties even in settings with many tied event times, inferential alignment between the p-value and confidence interval is guaranteed, and implementation is straightforward using commonly used software. Copyright © 2018 John Wiley & Sons, Ltd.

  6. The performance of different propensity score methods for estimating marginal hazard ratios.

    PubMed

    Austin, Peter C

    2013-07-20

    Propensity score methods are increasingly being used to reduce or minimize the effects of confounding when estimating the effects of treatments, exposures, or interventions when using observational or non-randomized data. Under the assumption of no unmeasured confounders, previous research has shown that propensity score methods allow for unbiased estimation of linear treatment effects (e.g., differences in means or proportions). However, in biomedical research, time-to-event outcomes occur frequently. There is a paucity of research into the performance of different propensity score methods for estimating the effect of treatment on time-to-event outcomes. Furthermore, propensity score methods allow for the estimation of marginal or population-average treatment effects. We conducted an extensive series of Monte Carlo simulations to examine the performance of propensity score matching (1:1 greedy nearest-neighbor matching within propensity score calipers), stratification on the propensity score, inverse probability of treatment weighting (IPTW) using the propensity score, and covariate adjustment using the propensity score to estimate marginal hazard ratios. We found that both propensity score matching and IPTW using the propensity score allow for the estimation of marginal hazard ratios with minimal bias. Of these two approaches, IPTW using the propensity score resulted in estimates with lower mean squared error when estimating the effect of treatment in the treated. Stratification on the propensity score and covariate adjustment using the propensity score result in biased estimation of both marginal and conditional hazard ratios. Applied researchers are encouraged to use propensity score matching and IPTW using the propensity score when estimating the relative effect of treatment on time-to-event outcomes. Copyright © 2012 John Wiley & Sons, Ltd.

  7. Stratospheric HBr mixing ratio obtained from far infrared emission spectra

    NASA Technical Reports Server (NTRS)

    Park, J. H.; Carli, B.; Barbis, A.

    1989-01-01

    Emission features of HBr isotopes have been identified in high-resolution FIR emission spectra obtained with a balloon-borne Fourier-transform spectrometer in the spring of 1979 at 32 deg N latitude. When six single-scan spectra at a zenith angle of 93.2 deg were averaged, two features of HBr isotopes at 50.054 and 50.069/cm were obtained with a signal-to-noise ratio of 2.5. The volume mixing ratio retrieved from the average spectrum is 2.0 x 10 to the -11th, which is assumed to be constant above 28 km, with an uncertainty of 35 percent. This stratospheric amount of HBr is about the same as the current level of tropospheric organic bromine compounds, 25 pptv. Thus HBr could be the major stratospheric bromine species.

  8. Bias in Hazard Ratios Arising From Misclassification According to Self-Reported Weight and Height in Observational Studies of Body Mass Index and Mortality.

    PubMed

    Flegal, Katherine M; Kit, Brian K; Graubard, Barry I

    2018-01-01

    Misclassification of body mass index (BMI) categories arising from self-reported weight and height can bias hazard ratios in studies of BMI and mortality. We examined the effects on hazard ratios of such misclassification using national US survey data for 1976 through 2010 that had both measured and self-reported weight and height along with mortality follow-up for 48,763 adults and a subset of 17,405 healthy never-smokers. BMI was categorized as <22.5 (low), 22.5-24.9 (referent), 25.0-29.9 (overweight), 30.0-34.9 (class I obesity), and ≥35.0 (class II-III obesity). Misreporting at higher BMI categories tended to bias hazard ratios upwards for those categories, but that effect was augmented, counterbalanced, or even reversed by misreporting in other BMI categories, in particular those that affected the reference category. For example, among healthy male never-smokers, misclassifications affecting the overweight and the reference categories changed the hazard ratio for overweight from 0.85 with measured data to 1.24 with self-reported data. Both the magnitude and direction of bias varied according to the underlying hazard ratios in measured data, showing that findings on bias from one study should not be extrapolated to a study with different underlying hazard ratios. Because of misclassification effects, self-reported weight and height cannot reliably indicate the lowest-risk BMI category. Published by Oxford University Press on behalf of the Johns Hopkins Bloomberg School of Public Health 2017. This work is written by (a) US Government employee(s) and is in the public domain in the US.

  9. Estimating hazard ratios in cohort data with missing disease information due to death.

    PubMed

    Binder, Nadine; Herrnböck, Anne-Sophie; Schumacher, Martin

    2017-03-01

    In clinical and epidemiological studies information on the primary outcome of interest, that is, the disease status, is usually collected at a limited number of follow-up visits. The disease status can often only be retrieved retrospectively in individuals who are alive at follow-up, but will be missing for those who died before. Right-censoring the death cases at the last visit (ad-hoc analysis) yields biased hazard ratio estimates of a potential risk factor, and the bias can be substantial and occur in either direction. In this work, we investigate three different approaches that use the same likelihood contributions derived from an illness-death multistate model in order to more adequately estimate the hazard ratio by including the death cases into the analysis: a parametric approach, a penalized likelihood approach, and an imputation-based approach. We investigate to which extent these approaches allow for an unbiased regression analysis by evaluating their performance in simulation studies and on a real data example. In doing so, we use the full cohort with complete illness-death data as reference and artificially induce missing information due to death by setting discrete follow-up visits. Compared to an ad-hoc analysis, all considered approaches provide less biased or even unbiased results, depending on the situation studied. In the real data example, the parametric approach is seen to be too restrictive, whereas the imputation-based approach could almost reconstruct the original event history information. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Can environmental or occupational hazards alter the sex ratio at birth? A systematic review

    PubMed Central

    Terrell, Metrecia L.; Hartnett, Kathleen P.; Marcus, Michele

    2011-01-01

    More than 100 studies have examined whether environmental or occupational exposures of parents affect the sex ratio of their offspring at birth. For this review, we searched Medline and Web of Science using the terms ‘sex ratio at birth’ and ‘sex ratio and exposure’ for all dates, and reviewed bibliographies of relevant studies to find additional articles. This review focuses on exposures that have been the subject of at least four studies including polychlorinated biphenyls (PCBs), dioxins, pesticides, lead and other metals, radiation, boron, and g-forces. For paternal exposures, only dioxins and PCBs were consistently associated with sex ratios higher or lower than the expected 1.06. Dioxins were associated with a decreased proportion of male births, whereas PCBs were associated with an increased proportion of male births. There was limited evidence for a decrease in the proportion of male births after paternal exposure to DBCP, lead, methylmercury, non-ionizing radiation, ionizing radiation treatment for childhood cancer, boron, or g-forces. Few studies have found higher or lower sex ratios associated with maternal exposures. Studies in humans and animals have found a reduction in the number of male births associated with lower male fertility, but the mechanism by which environmental hazards might change the sex ratio has not yet been established. PMID:24149027

  11. The median hazard ratio: a useful measure of variance and general contextual effects in multilevel survival analysis.

    PubMed

    Austin, Peter C; Wagner, Philippe; Merlo, Juan

    2017-03-15

    Multilevel data occurs frequently in many research areas like health services research and epidemiology. A suitable way to analyze such data is through the use of multilevel regression models (MLRM). MLRM incorporate cluster-specific random effects which allow one to partition the total individual variance into between-cluster variation and between-individual variation. Statistically, MLRM account for the dependency of the data within clusters and provide correct estimates of uncertainty around regression coefficients. Substantively, the magnitude of the effect of clustering provides a measure of the General Contextual Effect (GCE). When outcomes are binary, the GCE can also be quantified by measures of heterogeneity like the Median Odds Ratio (MOR) calculated from a multilevel logistic regression model. Time-to-event outcomes within a multilevel structure occur commonly in epidemiological and medical research. However, the Median Hazard Ratio (MHR) that corresponds to the MOR in multilevel (i.e., 'frailty') Cox proportional hazards regression is rarely used. Analogously to the MOR, the MHR is the median relative change in the hazard of the occurrence of the outcome when comparing identical subjects from two randomly selected different clusters that are ordered by risk. We illustrate the application and interpretation of the MHR in a case study analyzing the hazard of mortality in patients hospitalized for acute myocardial infarction at hospitals in Ontario, Canada. We provide R code for computing the MHR. The MHR is a useful and intuitive measure for expressing cluster heterogeneity in the outcome and, thereby, estimating general contextual effects in multilevel survival analysis. © 2016 The Authors. Statistics in Medicine published by John Wiley & Sons Ltd. © 2016 The Authors. Statistics in Medicine published by John Wiley & Sons Ltd.

  12. The median hazard ratio: a useful measure of variance and general contextual effects in multilevel survival analysis

    PubMed Central

    Wagner, Philippe; Merlo, Juan

    2016-01-01

    Multilevel data occurs frequently in many research areas like health services research and epidemiology. A suitable way to analyze such data is through the use of multilevel regression models (MLRM). MLRM incorporate cluster‐specific random effects which allow one to partition the total individual variance into between‐cluster variation and between‐individual variation. Statistically, MLRM account for the dependency of the data within clusters and provide correct estimates of uncertainty around regression coefficients. Substantively, the magnitude of the effect of clustering provides a measure of the General Contextual Effect (GCE). When outcomes are binary, the GCE can also be quantified by measures of heterogeneity like the Median Odds Ratio (MOR) calculated from a multilevel logistic regression model. Time‐to‐event outcomes within a multilevel structure occur commonly in epidemiological and medical research. However, the Median Hazard Ratio (MHR) that corresponds to the MOR in multilevel (i.e., ‘frailty’) Cox proportional hazards regression is rarely used. Analogously to the MOR, the MHR is the median relative change in the hazard of the occurrence of the outcome when comparing identical subjects from two randomly selected different clusters that are ordered by risk. We illustrate the application and interpretation of the MHR in a case study analyzing the hazard of mortality in patients hospitalized for acute myocardial infarction at hospitals in Ontario, Canada. We provide R code for computing the MHR. The MHR is a useful and intuitive measure for expressing cluster heterogeneity in the outcome and, thereby, estimating general contextual effects in multilevel survival analysis. © 2016 The Authors. Statistics in Medicine published by John Wiley & Sons Ltd. PMID:27885709

  13. Changing tides: Adaptive monitoring, assessment, and management of pharmaceutical hazards in the environment through time.

    PubMed

    Gaw, Sally; Brooks, Bryan W

    2016-04-01

    Pharmaceuticals are ubiquitous contaminants in aquatic ecosystems. Adaptive monitoring, assessment, and management programs will be required to reduce the environmental hazards of pharmaceuticals of concern. Potentially underappreciated factors that drive the environmental dose of pharmaceuticals include regulatory approvals, marketing campaigns, pharmaceutical subsidies and reimbursement schemes, and societal acceptance. Sales data for 5 common antidepressants (duloxetine [Cymbalta], escitalopram [Lexapro], venlafaxine [Effexor], bupropion [Wellbutrin], and sertraline [Zoloft]) in the United States from 2004 to 2008 were modeled to explore how environmental hazards in aquatic ecosystems changed after patents were obtained or expired. Therapeutic hazard ratios for Effexor and Lexapro did not exceed 1; however, the therapeutic hazard ratio for Zoloft declined whereas the therapeutic hazard ratio for Cymbalta increased as a function of patent protection and sale patterns. These changes in therapeutic hazard ratios highlight the importance of considering current and future drivers of pharmaceutical use when prioritizing pharmaceuticals for water quality monitoring programs. When urban systems receiving discharges of environmental contaminants are examined, water quality efforts should identify, prioritize, and select target analytes presently in commerce for effluent monitoring and surveillance. © 2015 SETAC.

  14. Restricted mean survival time: an alternative to the hazard ratio for the design and analysis of randomized trials with a time-to-event outcome

    PubMed Central

    2013-01-01

    Background Designs and analyses of clinical trials with a time-to-event outcome almost invariably rely on the hazard ratio to estimate the treatment effect and implicitly, therefore, on the proportional hazards assumption. However, the results of some recent trials indicate that there is no guarantee that the assumption will hold. Here, we describe the use of the restricted mean survival time as a possible alternative tool in the design and analysis of these trials. Methods The restricted mean is a measure of average survival from time 0 to a specified time point, and may be estimated as the area under the survival curve up to that point. We consider the design of such trials according to a wide range of possible survival distributions in the control and research arm(s). The distributions are conveniently defined as piecewise exponential distributions and can be specified through piecewise constant hazards and time-fixed or time-dependent hazard ratios. Such designs can embody proportional or non-proportional hazards of the treatment effect. Results We demonstrate the use of restricted mean survival time and a test of the difference in restricted means as an alternative measure of treatment effect. We support the approach through the results of simulation studies and in real examples from several cancer trials. We illustrate the required sample size under proportional and non-proportional hazards, also the significance level and power of the proposed test. Values are compared with those from the standard approach which utilizes the logrank test. Conclusions We conclude that the hazard ratio cannot be recommended as a general measure of the treatment effect in a randomized controlled trial, nor is it always appropriate when designing a trial. Restricted mean survival time may provide a practical way forward and deserves greater attention. PMID:24314264

  15. Choline-to-N-acetyl aspartate and lipids-lactate-to-creatine ratios together with age assemble a significant Cox's proportional-hazards regression model for prediction of survival in high-grade gliomas.

    PubMed

    Roldan-Valadez, Ernesto; Rios, Camilo; Motola-Kuba, Daniel; Matus-Santos, Juan; Villa, Antonio R; Moreno-Jimenez, Sergio

    2016-11-01

    A long-lasting concern has prevailed for the identification of predictive biomarkers for high-grade gliomas (HGGs) using MRI. However, a consensus of which imaging parameters assemble a significant survival model is still missing in the literature; we investigated the significant positive or negative contribution of several MR biomarkers in this tumour prognosis. A retrospective cohort of supratentorial HGGs [11 glioblastoma multiforme (GBM) and 17 anaplastic astrocytomas] included 28 patients (9 females and 19 males, respectively, with a mean age of 50.4 years, standard deviation: 16.28 years; range: 13-85 years). Oedema and viable tumour measurements were acquired using regions of interest in T 1 weighted, T 2 weighted, fluid-attenuated inversion recovery, apparent diffusion coefficient (ADC) and MR spectroscopy (MRS). We calculated Kaplan-Meier curves and obtained Cox's proportional hazards. During the follow-up period (3-98 months), 17 deaths were recorded. The median survival time was 1.73 years (range, 0.287-8.947 years). Only 3 out of 20 covariates (choline-to-N-acetyl aspartate and lipids-lactate-to-creatine ratios and age) showed significance in explaining the variability in the survival hazards model; score test: χ 2 (3) = 9.098, p = 0.028. MRS metabolites overcome volumetric parameters of peritumoral oedema and viable tumour, as well as tumour region ADC measurements. Specific MRS ratios (Cho/Naa, L-L/Cr) might be considered in a regular follow-up for these tumours. Advances in knowledge: Cho/Naa ratio is the strongest survival predictor with a log-hazard function of 2.672 in GBM. Low levels of lipids-lactate/Cr ratio represent up to a 41.6% reduction in the risk of death in GBM.

  16. Choline-to-N-acetyl aspartate and lipids-lactate-to-creatine ratios together with age assemble a significant Cox's proportional-hazards regression model for prediction of survival in high-grade gliomas

    PubMed Central

    Rios, Camilo; Motola-Kuba, Daniel; Matus-Santos, Juan; Villa, Antonio R; Moreno-Jimenez, Sergio

    2016-01-01

    Objective: A long-lasting concern has prevailed for the identification of predictive biomarkers for high-grade gliomas (HGGs) using MRI. However, a consensus of which imaging parameters assemble a significant survival model is still missing in the literature; we investigated the significant positive or negative contribution of several MR biomarkers in this tumour prognosis. Methods: A retrospective cohort of supratentorial HGGs [11 glioblastoma multiforme (GBM) and 17 anaplastic astrocytomas] included 28 patients (9 females and 19 males, respectively, with a mean age of 50.4 years, standard deviation: 16.28 years; range: 13–85 years). Oedema and viable tumour measurements were acquired using regions of interest in T1 weighted, T2 weighted, fluid-attenuated inversion recovery, apparent diffusion coefficient (ADC) and MR spectroscopy (MRS). We calculated Kaplan–Meier curves and obtained Cox's proportional hazards. Results: During the follow-up period (3–98 months), 17 deaths were recorded. The median survival time was 1.73 years (range, 0.287–8.947 years). Only 3 out of 20 covariates (choline-to-N-acetyl aspartate and lipids-lactate-to-creatine ratios and age) showed significance in explaining the variability in the survival hazards model; score test: χ2 (3) = 9.098, p = 0.028. Conclusion: MRS metabolites overcome volumetric parameters of peritumoral oedema and viable tumour, as well as tumour region ADC measurements. Specific MRS ratios (Cho/Naa, L-L/Cr) might be considered in a regular follow-up for these tumours. Advances in knowledge: Cho/Naa ratio is the strongest survival predictor with a log-hazard function of 2.672 in GBM. Low levels of lipids–lactate/Cr ratio represent up to a 41.6% reduction in the risk of death in GBM. PMID:27626830

  17. Impaired fasting glucose, ancestry and waist-to-height ratio: main predictors of incident diagnosed diabetes in the Canary Islands.

    PubMed

    de León, A Cabrera; Coello, S Domínguez; González, D Almeida; Díaz, B Brito; Rodríguez, J C del Castillo; Hernández, A González; Aguirre-Jaime, A; Pérez, M del Cristo Rodríguez

    2012-03-01

    To estimate the incidence rate and risk factors for diabetes in the Canary Islands. A total of 5521 adults without diabetes were followed for a median of 3.5 years. Incident cases of diabetes were self-declared and validated in medical records. The following factors were assessed by Cox regression to estimate the hazard ratios for diabetes: impaired fasting glucose (5.6 mmol/l ≤ fasting glucose ≤ 6.9 mmol/l), BMI, waist-to-height ratio (≥ 0.55), insulin resistance (defined as triglycerides/HDL cholesterol ≥ 3), familial antecedents of diabetes, Canarian ancestry, smoking, alcohol intake, sedentary lifestyle, Mediterranean diet, social class and the metabolic syndrome. The incidence rate was 7.5/10(3) person-years (95% CI 6.4-8.8). The greatest risks were obtained for impaired fasting glucose (hazard ratio 2.6; 95% CI 1.8-3.8), Canarian ancestry (hazard ratio 1.9; 95% CI 1.0-3.4), waist-to-height ratio (hazard ratio 1.7; 95% CI 1.1-2.5), insulin resistance (hazard ratio 1.5; 95% CI 1.0-2.2) and paternal history of diabetes (hazard ratio 1.5; 95% CI 1.0-2.3). The metabolic syndrome (hazard ratio 1.9; 95% CI 1.3-2.8) and BMI ≥ 30 kg/m(2) (hazard ratio 1.7; 95% CI 1.0-2.7) were significant only when their effects were not adjusted for impaired fasting glucose and waist-to-height ratio, respectively. The incidence of diabetes in the Canary Islands is 1.5-fold higher than that in continental Spain and 1.7-fold higher than in the UK. The main predictors of diabetes were impaired fasting glucose, Canarian ancestry, waist-to-height ratio and insulin resistance. The metabolic syndrome predicted diabetes only when its effect was not adjusted for impaired fasting glucose. In individuals with Canarian ancestry, genetic susceptibility studies may be advisable. In order to propose preventive strategies, impaired fasting glucose, waist-to-height ratio and triglyceride/HDL cholesterol should be used to identify subjects with an increased risk of developing diabetes.

  18. Effect of liquid-to-solid ratio on semi-solid Fenton process in hazardous solid waste detoxication.

    PubMed

    Hu, Li-Fang; Feng, Hua-Jun; Long, Yu-Yang; Zheng, Yuan-Ge; Fang, Cheng-Ran; Shen, Dong-Sheng

    2011-01-01

    The liquid-to-solid ratio (L/S) of semi-solid Fenton process (SSFP) designated for hazardous solid waste detoxication was investigated. The removal and minimization effects of o-nitroaniline (ONA) in simulate solid waste residue (SSWR) from organic arsenic industry was evaluated by total organic carbon (TOC) and ONA removal efficiency, respectively. Initially, Box-Behnken design (BBD) and response surface methodology (RSM) were used to optimize the key factors of SSFP. Results showed that the removal rates of TOC and ONA decreased as L/S increased. Subsequently, four target initial ONA concentrations including 100 mg kg(-1), 1 g kg(-1), 10 g kg(-1), and 100 gk g(-1) on a dry basis were evaluated for the effect of L/S. A significant cubic empirical model between the initial ONA concentration and L/S was successfully developed to predict the optimal L/S for given initial ONA concentration for SSFP. Moreover, an optimized operation strategy of multi-SSFP for different cases was determined based on the residual target pollutant concentration and the corresponding environmental conditions. It showed that the total L/S of multi-SSFP in all tested scenarios was no greater than 3.8, which is lower than the conventional slurry systems (L/S ≥ 5). The multi-SSFP is environment-friendly when it used for detoxication of hazardous solid waste contaminated by ONA and provides a potential method for the detoxication of hazardous solid waste contaminated by organics. Copyright © 2010 Elsevier Ltd. All rights reserved.

  19. Cancer Survival Estimates Due to Non-Uniform Loss to Follow-Up and Non-Proportional Hazards

    PubMed

    K M, Jagathnath Krishna; Mathew, Aleyamma; Sara George, Preethi

    2017-06-25

    Background: Cancer survival depends on loss to follow-up (LFU) and non-proportional hazards (non-PH). If LFU is high, survival will be over-estimated. If hazard is non-PH, rank tests will provide biased inference and Cox-model will provide biased hazard-ratio. We assessed the bias due to LFU and non-PH factor in cancer survival and provided alternate methods for unbiased inference and hazard-ratio. Materials and Methods: Kaplan-Meier survival were plotted using a realistic breast cancer (BC) data-set, with >40%, 5-year LFU and compared it using another BC data-set with <15%, 5-year LFU to assess the bias in survival due to high LFU. Age at diagnosis of the latter data set was used to illustrate the bias due to a non-PH factor. Log-rank test was employed to assess the bias in p-value and Cox-model was used to assess the bias in hazard-ratio for the non-PH factor. Schoenfeld statistic was used to test the non-PH of age. For the non-PH factor, we employed Renyi statistic for inference and time dependent Cox-model for hazard-ratio. Results: Five-year BC survival was 69% (SE: 1.1%) vs. 90% (SE: 0.7%) for data with low vs. high LFU respectively. Age (<45, 46-54 & >54 years) was a non-PH factor (p-value: 0.036). However, survival by age was significant (log-rank p-value: 0.026), but not significant using Renyi statistic (p=0.067). Hazard ratio (HR) for age using Cox-model was 1.012 (95%CI: 1.004 -1.019) and the same using time-dependent Cox-model was in the other direction (HR: 0.997; 95% CI: 0.997- 0.998). Conclusion: Over-estimated survival was observed for cancer with high LFU. Log-rank statistic and Cox-model provided biased results for non-PH factor. For data with non-PH factors, Renyi statistic and time dependent Cox-model can be used as alternate methods to obtain unbiased inference and estimates. Creative Commons Attribution License

  20. A comparison of methods used to obtain age ratios of snow and Canada geese

    USGS Publications Warehouse

    Higgins, K.F.; Linder, R.L.; Springer, P.F.

    1969-01-01

    The validity of group counts, cannon-net catches, and hunter-bag checks for estimating productivity of lesser snow geese (Anser caerulescens caerulescens) and small Canada geese (Branta canadensis hutchinsii-parvipes complex) was studied at Sand Lake National Wildlife Refuge during the falls of 1965 and 1966. Age ratios of snow geese obtained from net-trapped samples were significantly higher (P < 0.01) than from group counts at the same site. Immature snow geese were shot in a significantly greater (P < 0.01) proportion than they existed in the population as determined by group counts. Cannon-net catches and hunter-bag checks of snow and Canada geese yielded age ratios which were biased because of behavioral characteristics of the geese. Immatures of both species were less wary of trap equipment and immature snow geese were more vulnerable to the gun than adults. It was believed that age ratios from group counts of snow geese were more representative of the population than those from net catches and hunter-bag checks. Sex ratios of net-trapped geese showed a preponderance of males for adult Canada and adult and immature snow geese, whereas females were predominant in the immature segment of Canada geese. Hunter selectivity of blue- or white-phase snow geese was not observed at Sand Lake Refuge. Differential vulnerability to hunting between snow and Canada geese resulted from differences m feeding-flight behavior.

  1. Method for obtaining a collimated near-unity aspect ratio output beam from a DFB-GSE laser with good beam quality.

    PubMed

    Liew, S K; Carlson, N W

    1992-05-20

    A simple method for obtaining a collimated near-unity aspect ratio output beam from laser sources with extremely large (> 100:1) aspect ratios is demonstrated by using a distributed-feedback grating-surfaceemitting laser. Far-field power-in-the-bucket measurements of the laser indicate good beam quality with a high Strehl ratio.

  2. Hazard Regression Models of Early Mortality in Trauma Centers

    PubMed Central

    Clark, David E; Qian, Jing; Winchell, Robert J; Betensky, Rebecca A

    2013-01-01

    Background Factors affecting early hospital deaths after trauma may be different from factors affecting later hospital deaths, and the distribution of short and long prehospital times may vary among hospitals. Hazard regression (HR) models may therefore be more useful than logistic regression (LR) models for analysis of trauma mortality, especially when treatment effects at different time points are of interest. Study Design We obtained data for trauma center patients from the 2008–9 National Trauma Data Bank (NTDB). Cases were included if they had complete data for prehospital times, hospital times, survival outcome, age, vital signs, and severity scores. Cases were excluded if pulseless on admission, transferred in or out, or ISS<9. Using covariates proposed for the Trauma Quality Improvement Program and an indicator for each hospital, we compared LR models predicting survival at 8 hours after injury to HR models with survival censored at 8 hours. HR models were then modified to allow time-varying hospital effects. Results 85,327 patients in 161 hospitals met inclusion criteria. Crude hazards peaked initially, then steadily declined. When hazard ratios were assumed constant in HR models, they were similar to odds ratios in LR models associating increased mortality with increased age, firearm mechanism, increased severity, more deranged physiology, and estimated hospital-specific effects. However, when hospital effects were allowed to vary by time, HR models demonstrated that hospital outliers were not the same at different times after injury. Conclusions HR models with time-varying hazard ratios reveal inconsistencies in treatment effects, data quality, and/or timing of early death among trauma centers. HR models are generally more flexible than LR models, can be adapted for censored data, and potentially offer a better tool for analysis of factors affecting early death after injury. PMID:23036828

  3. Two models for evaluating landslide hazards

    USGS Publications Warehouse

    Davis, J.C.; Chung, C.-J.; Ohlmacher, G.C.

    2006-01-01

    Two alternative procedures for estimating landslide hazards were evaluated using data on topographic digital elevation models (DEMs) and bedrock lithologies in an area adjacent to the Missouri River in Atchison County, Kansas, USA. The two procedures are based on the likelihood ratio model but utilize different assumptions. The empirical likelihood ratio model is based on non-parametric empirical univariate frequency distribution functions under an assumption of conditional independence while the multivariate logistic discriminant model assumes that likelihood ratios can be expressed in terms of logistic functions. The relative hazards of occurrence of landslides were estimated by an empirical likelihood ratio model and by multivariate logistic discriminant analysis. Predictor variables consisted of grids containing topographic elevations, slope angles, and slope aspects calculated from a 30-m DEM. An integer grid of coded bedrock lithologies taken from digitized geologic maps was also used as a predictor variable. Both statistical models yield relative estimates in the form of the proportion of total map area predicted to already contain or to be the site of future landslides. The stabilities of estimates were checked by cross-validation of results from random subsamples, using each of the two procedures. Cell-by-cell comparisons of hazard maps made by the two models show that the two sets of estimates are virtually identical. This suggests that the empirical likelihood ratio and the logistic discriminant analysis models are robust with respect to the conditional independent assumption and the logistic function assumption, respectively, and that either model can be used successfully to evaluate landslide hazards. ?? 2006.

  4. Regression dilution in the proportional hazards model.

    PubMed

    Hughes, M D

    1993-12-01

    The problem of regression dilution arising from covariate measurement error is investigated for survival data using the proportional hazards model. The naive approach to parameter estimation is considered whereby observed covariate values are used, inappropriately, in the usual analysis instead of the underlying covariate values. A relationship between the estimated parameter in large samples and the true parameter is obtained showing that the bias does not depend on the form of the baseline hazard function when the errors are normally distributed. With high censorship, adjustment of the naive estimate by the factor 1 + lambda, where lambda is the ratio of within-person variability about an underlying mean level to the variability of these levels in the population sampled, removes the bias. As censorship increases, the adjustment required increases and when there is no censorship is markedly higher than 1 + lambda and depends also on the true risk relationship.

  5. Hazard Maps in the Classroom.

    ERIC Educational Resources Information Center

    Cross, John A.

    1988-01-01

    Emphasizes the use of geophysical hazard maps and illustrates how they can be used in the classroom from kindergarten to college level. Depicts ways that hazard maps of floods, landslides, earthquakes, volcanoes, and multi-hazards can be integrated into classroom instruction. Tells how maps may be obtained. (SLM)

  6. Detailed pressure distribution measurements obtained on several configurations of an aspect-ratio-7 variable twist wing

    NASA Technical Reports Server (NTRS)

    Holbrook, G. T.; Dunham, D. M.

    1985-01-01

    Detailed pressure distribution measurements were made for 11 twist configurations of a unique, multisegmented wing model having an aspect ratio of 7 and a taper ratio of 1. These configurations encompassed span loads ranging from that of an untwisted wing to simple flapped wings both with and without upper-surface spoilers attached. For each of the wing twist configurations, electronic scanning pressure transducers were used to obtain 580 surface pressure measurements over the wing in about 0.1 sec. Integrated pressure distribution measurements compared favorably with force-balance measurements of lift on the model when the model centerbody lift was included. Complete plots and tabulations of the pressure distribution data for each wing twist configuration are provided.

  7. The hazards of hazard identification in environmental epidemiology.

    PubMed

    Saracci, Rodolfo

    2017-08-09

    Hazard identification is a major scientific challenge, notably for environmental epidemiology, and is often surrounded, as the recent case of glyphosate shows, by debate arising in the first place by the inherently problematic nature of many components of the identification process. Particularly relevant in this respect are components less amenable to logical or mathematical formalization and essentially dependent on scientists' judgment. Four such potentially hazardous components that are capable of distorting the correct process of hazard identification are reviewed and discussed from an epidemiologist perspective: (1) lexical mix-up of hazard and risk (2) scientific questions as distinct from testable hypotheses, and implications for the hierarchy of strength of evidence obtainable from different types of study designs (3) assumptions in prior beliefs and model choices and (4) conflicts of interest. Four suggestions are put forward to strengthen a process that remains in several aspects judgmental, but not arbitrary, in nature.

  8. Orbital and suborbital variability in North Atlantic bottom water temperature obtained from deep-sea ostracod Mg/Ca ratios

    USGS Publications Warehouse

    Cronin, T. M.; Dwyer, G.S.; Baker, P.A.; Rodriguez-Lazaro, J.; DeMartino, D.M.

    2000-01-01

    Magnesium/calcium (Mg/Ca) ratios were measured in the deep-sea ostracod (Crustacea) genus Krithe from Chain core 82-24-4PC from the western mid-Atlantic Ridge (3427 m) in order to estimate ocean circulation and bottom water temperature (BWT) variability over the past 200,000 years. Mg/Ca ratios have been used as a paleothermometer because the ratios are controlled primarily by ambient water temperatures at the time the organism secretes its adult carapace. Over the past two glacial–interglacial cycles, Mg/Ca values oscillated between about 7 mmol/mol and 12 mmol/mol, equivalent to a BWT range of 0 to >3.5°C. The lowest values were obtained on specimens from glacial marine isotope stages (MISs) 2, 4 and 6; the highest values were obtained from specimens from the early part of the Holocene interglacial (MIS 1), and also from MISs 5 and 7. These trends suggest that BWTs in the North Atlantic Ocean fluctuate over orbital time scales.Suborbital variability in Mg/Ca ratios and BWT was also observed for the past 100,000 years. Ratios rose from ∼8 mmol/mol to ∼10 mmol/mol (implying a BWT increase of ∼1 to 3°C) during 14 Mg/Ca excursions. The highest ratios were found in Krithe dated at approximately 32, 36–38, 43, 48, 73, 85 and 93 ka. Although the age model for the Chain 82-24-4PC and temporal resolution do not allow precise correlation, some of these deep-sea bottom temperature excursions appear to correspond to Heinrich events recorded in other regions of the North Atlantic and perhaps Dansgaard–Oeschger interstadial events recorded in Greenland ice cores. If confirmed, this would support the hypothesis that millennial-scale oscillations of climate in the North Atlantic are capable of affecting global climate via thermohaline circulation changes.

  9. Use of the p,p'-DDD: p,p'-DDE concentration ratio to trace contaminant migration from a hazardous waste site.

    PubMed

    Pinkney, Alfred E; McGowan, Peter C

    2006-09-01

    For approximately 50 years, beginning in the 1920s, hazardous wastes were disposed in an 11-hectare area of the Marine Corps Base (MCB) Quantico, Virginia, USA known as the Old Landfill. Polychlorinated biphenyls (PCBs) and DDT compounds were the primary contaminants of concern. These contaminants migrated into the sediments of a 78-hectare area of the Potomac River, the Quantico Embayment. Fish tissue contamination resulted in the MCB posting signs along the embayment shoreline warning fishermen to avoid consumption. In this paper, we interpret total PCB (t-PCBs) and total DDT (t-DDT, sum of six DDT, DDD, and DDE isomers) data from monitoring studies. We use the ratio of p,p'-DDD to p,p'-DDE concentrations as a tracer to distinguish site-related from regional contamination. The median DDD/DDE ratio in Quantico Embayment sediments (3.5) was significantly higher than the median ratio (0.71) in sediments from nearby Powells Creek, used as a reference area. In general, t-PCBs and t-DDT concentrations were significantly higher in killifish (Fundulus diaphanus) and carp (Cyprinus carpio) from the Quantico Embayment compared with Powells Creek. For both species, Quantico Embayment fish had mean or median DDD/DDE ratios greater than one. Median ratios were significantly higher in Quantico Embayment (4.6) than Powells Creek (0.28) whole body carp. In contrast, t-PCBs and t-DDT in channel catfish (Ictalurus punctatus) fillets were similar in Quantico Embayment and Powells Creek collections, with median ratios of 0.34 and 0.26, respectively. Differences between species may be attributable to movement (carp and killifish being more localized) and feeding patterns (carp ingesting sediment while feeding). We recommend that environmental scientists use this ratio when investigating sites with DDT contamination.

  10. Simulation-Based Probabilistic Tsunami Hazard Analysis: Empirical and Robust Hazard Predictions

    NASA Astrophysics Data System (ADS)

    De Risi, Raffaele; Goda, Katsuichiro

    2017-08-01

    Probabilistic tsunami hazard analysis (PTHA) is the prerequisite for rigorous risk assessment and thus for decision-making regarding risk mitigation strategies. This paper proposes a new simulation-based methodology for tsunami hazard assessment for a specific site of an engineering project along the coast, or, more broadly, for a wider tsunami-prone region. The methodology incorporates numerous uncertain parameters that are related to geophysical processes by adopting new scaling relationships for tsunamigenic seismic regions. Through the proposed methodology it is possible to obtain either a tsunami hazard curve for a single location, that is the representation of a tsunami intensity measure (such as inundation depth) versus its mean annual rate of occurrence, or tsunami hazard maps, representing the expected tsunami intensity measures within a geographical area, for a specific probability of occurrence in a given time window. In addition to the conventional tsunami hazard curve that is based on an empirical statistical representation of the simulation-based PTHA results, this study presents a robust tsunami hazard curve, which is based on a Bayesian fitting methodology. The robust approach allows a significant reduction of the number of simulations and, therefore, a reduction of the computational effort. Both methods produce a central estimate of the hazard as well as a confidence interval, facilitating the rigorous quantification of the hazard uncertainties.

  11. Rockfall Hazard Process Assessment : [Project Summary

    DOT National Transportation Integrated Search

    2017-10-01

    The Montana Department of Transportation (MDT) implemented its Rockfall Hazard Rating System (RHRS) between 2003 and 2005, obtaining information on the state's rock slopes and their associated hazards. The RHRS data facilitated decision-making in an ...

  12. Use of generalized population ratios to obtain Fe XV line intensities and linewidths at high electron densities

    NASA Technical Reports Server (NTRS)

    Kastner, S. O.; Bhatia, A. K.

    1980-01-01

    A generalized method for obtaining individual level population ratios is used to obtain relative intensities of extreme ultraviolet Fe XV emission lines in the range 284-500 A, which are density dependent for electron densities in the tokamak regime or higher. Four lines in particular are found to attain quite high intensities in the high-density limit. The same calculation provides inelastic contributions to linewidths. The method connects level populations and level widths through total probabilities t(ij), related to 'taboo' probabilities of Markov chain theory. The t(ij) are here evaluated for a real atomic system, being therefore of potential interest to random-walk theorists who have been limited to idealized systems characterized by simplified transition schemes.

  13. Use of generalized population ratios to obtain Fe XV line intensities and linewidths at high electron densities

    NASA Astrophysics Data System (ADS)

    Kastner, S. O.; Bhatia, A. K.

    1980-08-01

    A generalized method for obtaining individual level population ratios is used to obtain relative intensities of extreme ultraviolet Fe XV emission lines in the range 284-500 A, which are density dependent for electron densities in the tokamak regime or higher. Four lines in particular are found to attain quite high intensities in the high-density limit. The same calculation provides inelastic contributions to linewidths. The method connects level populations and level widths through total probabilities t(ij), related to 'taboo' probabilities of Markov chain theory. The t(ij) are here evaluated for a real atomic system, being therefore of potential interest to random-walk theorists who have been limited to idealized systems characterized by simplified transition schemes.

  14. Near-Earth object hazardous impact: A Multi-Criteria Decision Making approach.

    PubMed

    Sánchez-Lozano, J M; Fernández-Martínez, M

    2016-11-16

    The impact of a near-Earth object (NEO) may release large amounts of energy and cause serious damage. Several NEO hazard studies conducted over the past few years provide forecasts, impact probabilities and assessment ratings, such as the Torino and Palermo scales. These high-risk NEO assessments involve several criteria, including impact energy, mass, and absolute magnitude. The main objective of this paper is to provide the first Multi-Criteria Decision Making (MCDM) approach to classify hazardous NEOs. Our approach applies a combination of two methods from a widely utilized decision making theory. Specifically, the Analytic Hierarchy Process (AHP) methodology is employed to determine the criteria weights, which influence the decision making, and the Technique for Order Performance by Similarity to Ideal Solution (TOPSIS) is used to obtain a ranking of alternatives (potentially hazardous NEOs). In addition, NEO datasets provided by the NASA Near-Earth Object Program are utilized. This approach allows the classification of NEOs by descending order of their TOPSIS ratio, a single quantity that contains all of the relevant information for each object.

  15. Detecting and monitoring water stress states in maize crops using spectral ratios obtained in the photosynthetic domain

    NASA Astrophysics Data System (ADS)

    Baranoski, Gladimir V. G.; Van Leeuwen, Spencer R.

    2017-07-01

    The reliable detection and monitoring of changes in the water status of crops composed of plants like maize, a highly adaptable C4 species in large demand for both food and biofuel production, are longstanding remote sensing goals. Existing procedures employed to achieve these goals rely predominantly on the spectral signatures of plant leaves in the infrared domain where the light absorption within the foliar tissues is dominated by water. It has been suggested that such procedures could be implemented using subsurface reflectance to transmittance ratios obtained in the visible (photosynthetic) domain with the assistance of polarization devices. However, the experiments leading to this proposition were performed on detached maize leaves, which were not influenced by the whole (living) plant's adaptation mechanisms to water stress. In this work, we employ predictive simulations of light-leaf interactions in the photosynthetic domain to demonstrate that the living specimens' physiological responses to dehydration stress should be taken into account in this context. Our findings also indicate that a reflectance to transmittance ratio obtained in the photosynthetic domain at a lower angle of incidence without the use of polarization devices may represent a cost-effective alternative for the assessment of water stress states in maize crops.

  16. Comparison of exact, efron and breslow parameter approach method on hazard ratio and stratified cox regression model

    NASA Astrophysics Data System (ADS)

    Fatekurohman, Mohamat; Nurmala, Nita; Anggraeni, Dian

    2018-04-01

    Lungs are the most important organ, in the case of respiratory system. Problems related to disorder of the lungs are various, i.e. pneumonia, emphysema, tuberculosis and lung cancer. Comparing all those problems, lung cancer is the most harmful. Considering about that, the aim of this research applies survival analysis and factors affecting the endurance of the lung cancer patient using comparison of exact, Efron and Breslow parameter approach method on hazard ratio and stratified cox regression model. The data applied are based on the medical records of lung cancer patients in Jember Paru-paru hospital on 2016, east java, Indonesia. The factors affecting the endurance of the lung cancer patients can be classified into several criteria, i.e. sex, age, hemoglobin, leukocytes, erythrocytes, sedimentation rate of blood, therapy status, general condition, body weight. The result shows that exact method of stratified cox regression model is better than other. On the other hand, the endurance of the patients is affected by their age and the general conditions.

  17. Carbon Structure Hazard Control

    NASA Technical Reports Server (NTRS)

    Yoder, Tommy; Greene, Ben; Porter, Alan

    2015-01-01

    Carbon composite structures are widely used in virtually all advanced technology industries for a multitude of applications. The high strength-to-weight ratio and resistance to aggressive service environments make them highly desirable. Automotive, aerospace, and petroleum industries extensively use, and will continue to use, this enabling technology. As a result of this broad range of use, field and test personnel are increasingly exposed to hazards associated with these structures. No single published document exists to address the hazards and make recommendations for the hazard controls required for the different exposure possibilities from damaged structures including airborne fibers, fly, and dust. The potential for personnel exposure varies depending on the application or manipulation of the structure. The effect of exposure to carbon hazards is not limited to personnel, protection of electronics and mechanical equipment must be considered as well. The various exposure opportunities defined in this document include pre-manufacturing fly and dust, the cured structure, manufacturing/machining, post-event cleanup, and post-event test and/or evaluation. Hazard control is defined as it is applicable or applied for the specific exposure opportunity. The carbon exposure hazard includes fly, dust, fiber (cured/uncured), and matrix vapor/thermal decomposition products. By using the recommendations in this document, a high level of confidence can be assured for the protection of personnel and equipment.

  18. Comparison of Fuzzy-Based Models in Landslide Hazard Mapping

    NASA Astrophysics Data System (ADS)

    Mijani, N.; Neysani Samani, N.

    2017-09-01

    Landslide is one of the main geomorphic processes which effects on the development of prospect in mountainous areas and causes disastrous accidents. Landslide is an event which has different uncertain criteria such as altitude, slope, aspect, land use, vegetation density, precipitation, distance from the river and distance from the road network. This research aims to compare and evaluate different fuzzy-based models including Fuzzy Analytic Hierarchy Process (Fuzzy-AHP), Fuzzy Gamma and Fuzzy-OR. The main contribution of this paper reveals to the comprehensive criteria causing landslide hazard considering their uncertainties and comparison of different fuzzy-based models. The quantify of evaluation process are calculated by Density Ratio (DR) and Quality Sum (QS). The proposed methodology implemented in Sari, one of the city of Iran which has faced multiple landslide accidents in recent years due to the particular environmental conditions. The achieved results of accuracy assessment based on the quantifier strated that Fuzzy-AHP model has higher accuracy compared to other two models in landslide hazard zonation. Accuracy of zoning obtained from Fuzzy-AHP model is respectively 0.92 and 0.45 based on method Precision (P) and QS indicators. Based on obtained landslide hazard maps, Fuzzy-AHP, Fuzzy Gamma and Fuzzy-OR respectively cover 13, 26 and 35 percent of the study area with a very high risk level. Based on these findings, fuzzy-AHP model has been selected as the most appropriate method of zoning landslide in the city of Sari and the Fuzzy-gamma method with a minor difference is in the second order.

  19. Occupational health hazards in veterinary medicine: Zoonoses and other biological hazards

    PubMed Central

    Epp, Tasha; Waldner, Cheryl

    2012-01-01

    This study describes biological hazards reported by veterinarians working in western Canada obtained through a self-administered mailed questionnaire. The potential occupational hazards included as biological hazards were zoonotic disease events, exposure to rabies, injuries due to bites and scratches, and allergies. Only 16.7% (136/812) of responding veterinarians reported the occurrence of a zoonosis or exposure to rabies in the past 5 years; the most commonly reported event was ringworm. Most bites and scratches (86%) described by 586 veterinarians involved encounters with cats; 81% of the resulting 163 infections were due to cat bites or scratches. Approximately 38% of participants reported developing an allergy during their career, with 41% of the affected individuals altering the way they practiced in response to their allergy. PMID:22851775

  20. Prechemotherapy neutrophil : lymphocyte ratio is superior to the platelet : lymphocyte ratio as a prognostic indicator for locally advanced esophageal squamous cell cancer treated with neoadjuvant chemotherapy.

    PubMed

    Ji, W H; Jiang, Y H; Ji, Y L; Li, B; Mao, W M

    2016-07-01

    The study aimed to evaluate the prognostic significance of prechemotherapy neutrophil to lymphocyte ratio and platelet to lymphocyte ratio, and preoperative neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in locally advanced esophageal squamous cell cancer. We analyzed retrospectively locally advanced esophageal squamous cell cancer patients who had received neoadjuvant chemotherapy before undergoing a radical esophagectomy between 2009 and 2012. Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio before chemotherapy and before the surgery were calculated. Univariate analyses showed that prechemotherapy neutrophil to lymphocyte ratio >5 (P = 0.048, hazard ratio = 2.86; 95% confidence interval: 1.01-8.12) and prechemotherapy platelet to lymphocyte ratio >130 (P = 0.025, hazard ratio = 5.50; 95% confidence interval: 1.23-24.55) were associated significantly with overall survival (OS), and prechemotherapy platelet to lymphocyte ratio >130 (P = 0.026, hazard ratio = 3.18; 95% confidence interval: 1.15-8.85) was associated significantly with progression-free survival. However, only prechemotherapy neutrophil to lymphocyte ratio >5 (P = 0.024, hazard ratio = 3.50; 95% confidence interval: 1.18-10.40) remained significantly associated with OS in multivariate analyses. Neither preoperative neutrophil to lymphocyte ratio nor platelet to lymphocyte ratio was associated with OS or progression-free survival. The prechemotherapy neutrophil to lymphocyte ratio >5 to preoperative neutrophil to lymphocyte ratio ≤5 group showed significantly worse OS than the prechemotherapy neutrophil to lymphocyte ratio ≤5 to preoperative neutrophil to lymphocyte ratio ≤5 group (P = 0.050). The prechemotherapy platelet to lymphocyte ratio >130 to preoperative platelet to lymphocyte ratio ≤130 group (P = 0.016) and platelet to lymphocyte ratio >130 to preoperative platelet to lymphocyte ratio >130 group (P = 0.042) showed significantly worse OS than the

  1. The prospect of hazardous sludge reduction through gasification process

    NASA Astrophysics Data System (ADS)

    Hakiki, R.; Wikaningrum, T.; Kurniawan, T.

    2018-01-01

    Biological sludge generated from centralized industrial WWTP is classified as toxic and hazardous waste based on the Indonesian’s Government Regulation No. 101/2014. The amount of mass and volume of sludge produced have an impact in the cost to manage or to dispose. The main objective of this study is to identify the opportunity of gasification technology which can be applied to reduce hazardous sludge quantity before sending to the final disposal. This preliminary study covers the technical and economic assessment of the application of gasification process, which was a combination of lab-scale experimental results and assumptions based on prior research. The results showed that the process was quite effective in reducing the amount and volume of hazardous sludge which results in reducing the disposal costs without causing negative impact on the environment. The reduced mass are moisture and volatile carbon which are decomposed, while residues are fix carbon and other minerals which are not decomposed by thermal process. The economical simulation showed that the project will achieve payback period in 2.5 years, IRR value of 53 % and BC Ratio of 2.3. The further study in the pilot scale to obtain the more accurate design and calculations is recommended.

  2. Hazardous waste incinerators under waste uncertainty: balancing and throughput maximization via heat recuperation.

    PubMed

    Tsiliyannis, Christos Aristeides

    2013-09-01

    Hazardous waste incinerators (HWIs) differ substantially from thermal power facilities, since instead of maximizing energy production with the minimum amount of fuel, they aim at maximizing throughput. Variations in quantity or composition of received waste loads may significantly diminish HWI throughput (the decisive profit factor), from its nominal design value. A novel formulation of combustion balance is presented, based on linear operators, which isolates the wastefeed vector from the invariant combustion stoichiometry kernel. Explicit expressions for the throughput are obtained, in terms of incinerator temperature, fluegas heat recuperation ratio and design parameters, for an arbitrary number of wastes, based on fundamental principles (mass and enthalpy balances). The impact of waste variations, of recuperation ratio and of furnace temperature is explicitly determined. It is shown that in the presence of waste uncertainty, the throughput may be a decreasing or increasing function of incinerator temperature and recuperation ratio, depending on the sign of a dimensionless parameter related only to the uncertain wastes. The dimensionless parameter is proposed as a sharp a' priori waste 'fingerprint', determining the necessary increase or decrease of manipulated variables (recuperation ratio, excess air, auxiliary fuel feed rate, auxiliary air flow) in order to balance the HWI and maximize throughput under uncertainty in received wastes. A 10-step procedure is proposed for direct application subject to process capacity constraints. The results may be useful for efficient HWI operation and for preparing hazardous waste blends. Copyright © 2013 Elsevier Ltd. All rights reserved.

  3. Seismic hazard in the eastern United States

    USGS Publications Warehouse

    Mueller, Charles; Boyd, Oliver; Petersen, Mark D.; Moschetti, Morgan P.; Rezaeian, Sanaz; Shumway, Allison

    2015-01-01

    The U.S. Geological Survey seismic hazard maps for the central and eastern United States were updated in 2014. We analyze results and changes for the eastern part of the region. Ratio maps are presented, along with tables of ground motions and deaggregations for selected cities. The Charleston fault model was revised, and a new fault source for Charlevoix was added. Background seismicity sources utilized an updated catalog, revised completeness and recurrence models, and a new adaptive smoothing procedure. Maximum-magnitude models and ground motion models were also updated. Broad, regional hazard reductions of 5%–20% are mostly attributed to new ground motion models with stronger near-source attenuation. The revised Charleston fault geometry redistributes local hazard, and the new Charlevoix source increases hazard in northern New England. Strong increases in mid- to high-frequency hazard at some locations—for example, southern New Hampshire, central Virginia, and eastern Tennessee—are attributed to updated catalogs and/or smoothing.

  4. Probabilistic Seismic Hazard Maps for Ecuador

    NASA Astrophysics Data System (ADS)

    Mariniere, J.; Beauval, C.; Yepes, H. A.; Laurence, A.; Nocquet, J. M.; Alvarado, A. P.; Baize, S.; Aguilar, J.; Singaucho, J. C.; Jomard, H.

    2017-12-01

    A probabilistic seismic hazard study is led for Ecuador, a country facing a high seismic hazard, both from megathrust subduction earthquakes and shallow crustal moderate to large earthquakes. Building on the knowledge produced in the last years in historical seismicity, earthquake catalogs, active tectonics, geodynamics, and geodesy, several alternative earthquake recurrence models are developed. An area source model is first proposed, based on the seismogenic crustal and inslab sources defined in Yepes et al. (2016). A slightly different segmentation is proposed for the subduction interface, with respect to Yepes et al. (2016). Three earthquake catalogs are used to account for the numerous uncertainties in the modeling of frequency-magnitude distributions. The hazard maps obtained highlight several source zones enclosing fault systems that exhibit low seismic activity, not representative of the geological and/or geodetical slip rates. Consequently, a fault model is derived, including faults with an earthquake recurrence model inferred from geological and/or geodetical slip rate estimates. The geodetical slip rates on the set of simplified faults are estimated from a GPS horizontal velocity field (Nocquet et al. 2014). Assumptions on the aseismic component of the deformation are required. Combining these alternative earthquake models in a logic tree, and using a set of selected ground-motion prediction equations adapted to Ecuador's different tectonic contexts, a mean hazard map is obtained. Hazard maps corresponding to the percentiles 16 and 84% are also derived, highlighting the zones where uncertainties on the hazard are highest.

  5. Stratified aspartate aminotransferase-to-platelet ratio index accurately predicts survival in hepatocellular carcinoma patients undergoing curative liver resection.

    PubMed

    Yang, Hao-Jie; Jiang, Jing-Hang; Yang, Yu-Ting; Guo, Zhe; Li, Ji-Jia; Liu, Xuan-Han; Lu, Fei; Zeng, Feng-Hua; Ye, Jin-Song; Zhang, Ke-Lan; Chen, Neng-Zhi; Xiang, Bang-De; Li, Le-Qun

    2017-03-01

    The aspartate aminotransferase-to-platelet ratio index has been reported to predict prognosis of patients with hepatocellular carcinoma. This study examined the prognostic potential of stratified aspartate aminotransferase-to-platelet ratio index for hepatocellular carcinoma patients undergoing curative liver resection. A total of 661 hepatocellular carcinoma patients were retrieved and the associations between aspartate aminotransferase-to-platelet ratio index and clinicopathological variables and survivals (overall survival and disease-free survival) were analyzed. Higher aspartate aminotransferase-to-platelet ratio index quartiles were significantly associated with poorer overall survival (p = 0.002) and disease-free survival (p = 0.001). Multivariate analysis showed aspartate aminotransferase-to-platelet ratio index to be an independent risk factor for overall survival (p = 0.018) and disease-free survival (p = 0.01). Patients in the highest aspartate aminotransferase-to-platelet ratio index quartile were at 44% greater risk of death than patients in the first quartile (hazard ratio = 1.445, 95% confidence interval = 1.081 - 1.931, p = 0.013), as well as 49% greater risk of recurrence (hazard ratio = 1.49, 95% confidence interval = 1.112-1.998, p = 0.008). Subgroup analysis also showed aspartate aminotransferase-to-platelet ratio index to be an independent predictor of poor overall survival and disease-free survival in patients positive for hepatitis B surface antigen or with cirrhosis (both p < 0.05). Similar results were obtained when aspartate aminotransferase-to-platelet ratio index was analyzed as a dichotomous variable with cutoff values of 0.25 and 0.62. Elevated preoperative aspartate aminotransferase-to-platelet ratio index may be independently associated with poor overall survival and disease-free survival in hepatocellular carcinoma patients following curative resection.

  6. Cause-specific mortality according to urine albumin creatinine ratio in the general population.

    PubMed

    Skaaby, Tea; Husemoen, Lise Lotte Nystrup; Ahluwalia, Tarunveer Singh; Rossing, Peter; Jørgensen, Torben; Thuesen, Betina Heinsbæk; Pisinger, Charlotta; Rasmussen, Knud; Linneberg, Allan

    2014-01-01

    Urine albumin creatinine ratio, UACR, is positively associated with all-cause mortality, cardiovascular disease and diabetes in observational studies. Whether a high UACR is also associated with other causes of death is unclear. We investigated the association between UACR and cause-specific mortality. We included a total of 9,125 individuals from two population-based studies, Monica10 and Inter99, conducted in 1993-94 and 1999-2001, respectively. Urine albumin creatinine ratio was measured from spot urine samples by standard methods. Information on causes of death was obtained from The Danish Register of Causes of Death until 31 December 2010. There were a total of 920 deaths, and the median follow-up was 11.3 years. Multivariable Cox regression analyses with age as underlying time axis showed statistically significant positive associations between UACR status and risk of all-cause mortality, endocrine nutritional and metabolic diseases, mental and behavioural disorders, diseases of the circulatory system, and diseases of the respiratory system with hazard ratios 1.56, 6.98, 2.34, 2.03, and 1.91, for the fourth UACR compared with the first, respectively. Using UACR as a continuous variable, we also found a statistically significant positive association with risk of death caused by diseases of the digestive system with a hazard ratio of 1.02 per 10 mg/g higher UACR. We found statistically significant positive associations between baseline UACR and death from all-cause mortality, endocrine nutritional and metabolic diseases, and diseases of the circulatory system and possibly mental and behavioural disorders, and diseases of the respiratory and digestive system.

  7. Occupational Psychosocial Hazards Among the Emerging US Green Collar Workforce.

    PubMed

    Fernandez, Cristina A; Moore, Kevin; McClure, Laura A; Caban-Martinez, Alberto J; LeBlanc, William G; Fleming, Lora E; Cifuentes, Manuel; Lee, David J

    2017-01-01

    To compare occupational psychosocial hazards in green collar versus non-green collar workers. Standard Occupational Classification codes were used to link the 2010 National Health Interview Survey to the 2010 Occupational Information Network Database. Multivariable logistic regressions were used to predict job insecurity, work life imbalance, and workplace harassment in green versus non-green collar workers. Most participants were white, non-Hispanic, 25 to 64 years of age, and obtained greater than a high school education. The majority of workers reported no job insecurity, work life imbalance, or workplace harassment. Relative to non-green collar workers (n = 12,217), green collar workers (n = 2,588) were more likely to report job insecurity (Odds ratio [OR] = 1.13; 95% confidence interval [CI] = 1.02 to 1.26) and work life imbalance (1.19; 1.05 to 1.35), but less likely to experience workplace harassment (0.77; 0.62 to 0.95). Continuous surveillance of occupational psychosocial hazards is recommended in this rapidly emerging workforce.

  8. An approach to trial design and analysis in the era of non-proportional hazards of the treatment effect.

    PubMed

    Royston, Patrick; Parmar, Mahesh K B

    2014-08-07

    Most randomized controlled trials with a time-to-event outcome are designed and analysed under the proportional hazards assumption, with a target hazard ratio for the treatment effect in mind. However, the hazards may be non-proportional. We address how to design a trial under such conditions, and how to analyse the results. We propose to extend the usual approach, a logrank test, to also include the Grambsch-Therneau test of proportional hazards. We test the resulting composite null hypothesis using a joint test for the hazard ratio and for time-dependent behaviour of the hazard ratio. We compute the power and sample size for the logrank test under proportional hazards, and from that we compute the power of the joint test. For the estimation of relevant quantities from the trial data, various models could be used; we advocate adopting a pre-specified flexible parametric survival model that supports time-dependent behaviour of the hazard ratio. We present the mathematics for calculating the power and sample size for the joint test. We illustrate the methodology in real data from two randomized trials, one in ovarian cancer and the other in treating cellulitis. We show selected estimates and their uncertainty derived from the advocated flexible parametric model. We demonstrate in a small simulation study that when a treatment effect either increases or decreases over time, the joint test can outperform the logrank test in the presence of both patterns of non-proportional hazards. Those designing and analysing trials in the era of non-proportional hazards need to acknowledge that a more complex type of treatment effect is becoming more common. Our method for the design of the trial retains the tools familiar in the standard methodology based on the logrank test, and extends it to incorporate a joint test of the null hypothesis with power against non-proportional hazards. For the analysis of trial data, we propose the use of a pre-specified flexible parametric model

  9. Hazard proximities of childhood cancers in Great Britain from 1953-80.

    PubMed Central

    Knox, E G; Gilman, E A

    1997-01-01

    STUDY OBJECTIVES: Firstly, to examine relationships between the birth and death addresses of children dying from leukaemia and cancer in Great Britain, and the sites of potential environmental hazards; and secondly to measure relative case densities close to, and at increasing distances from, different hazard types. DESIGN: Home address postcodes (PCs) and their map coordinates were identified at birth and at death in children who died from leukaemia or cancer. Potentially hazardous industrial addresses and PCs were listed from business and other directories, and map coordinates obtained from the Central Postcode Directory or else located directly on Ordnance Survey (OS) maps. Railway lines and motorways were digitised from OS maps. Numbers of deaths (and births) at successive radial distances from these hazards were counted and compared with expected numbers. The latter were based on a count of all PCs at similar distances. Relative case density ratios at successive distances from the hazards were obtained from observed and expected numbers, aggregated over similar sites. This was repeated for different hazard types and results were tested for evidence of systematic centrifugal case density gradients. PARTICIPANTS AND SETTING: All 22,458 children dying from leukaemia or cancer aged 0-15 years, in England, Wales, and Scotland, between 1953 and 1980. MAIN RESULTS: Relative excesses of leukaemias and of solid cancers were found near the following: (1) oil refineries, major oil storage installations, railside oil distribution terminals and factories making bitumen products; (2) motor car factories, coach builders, and car body repairers; (3) major users of petroleum products including manufacturers of solvents, paint sprayers, fibreglass fabricators, paint and varnish makers, plastics and detergent manufacturers, and galvanisers; (4) users of kilns and furnaces including steelworks, power stations, galvanisers, cement makers, brickworks, crematoria and aluminium, zinc

  10. Disseminating Landslide Hazard Information for California Local Government

    NASA Astrophysics Data System (ADS)

    Wills, C. J.

    2010-12-01

    Since 1969, the California Geological Survey has produced numerous maps showing landslide features and delineating potential slope-stability problem areas. These maps have been provided to local governments to encourage consideration of landslide hazards in planning and development decisions. Maps produced from 1986 through 1995 under the Landslide Hazard Mapping Act were advisory only, and their use by local government was never consistent. By contrast, maps of Zones of Required Investigation for seismically induced landslides produced under the Seismic Hazard Zoning Act since 1997 come with detailed guidelines and legal requirements. A legislative act that required landslide hazards be mapped and hazard maps disseminated to local government proved ineffective in landslide hazard mitigation. A later act with requirements that the hazard zone maps be used by local government proved more effective. Planning scenarios have proven to be an effective way of transmitting scientific information about natural hazards to emergency response professionals. Numerous earthquake planning scenarios have been prepared and used as the basis for emergency response exercises. An advantage of scenarios that include loss estimates is that the effects can be put in units of measure that everyone understands, principally deaths and dollars. HAZUS software available from FEMA allows calculation of losses for earthquake scenarios, but similar methods for landslides have not been developed. As part of the USGS Multi-Hazard Demonstration Project, we have estimated the landslide losses for a major west-coast winter storm scenario by developing a system based loosely on HAZUS. Data on landslide damage in past storms has been sparse and inconsistent, but a few data sets are available. The most detailed and complete available data on landslide damage was gathered by the City of Los Angeles following the 1978 storms. We extrapolate from that data to the entire state by first generalizing a

  11. Hazardous Material Transportation Risks in the Puget Sound Region

    DOT National Transportation Integrated Search

    1981-09-01

    In order to contribute to workable hazardous materials accident prevention and response systems, public safety risks of transporting hazardous materials in the Central Puget Sound Region of Washington State are determined. Risk spectrums are obtained...

  12. Confidence intervals for the first crossing point of two hazard functions.

    PubMed

    Cheng, Ming-Yen; Qiu, Peihua; Tan, Xianming; Tu, Dongsheng

    2009-12-01

    The phenomenon of crossing hazard rates is common in clinical trials with time to event endpoints. Many methods have been proposed for testing equality of hazard functions against a crossing hazards alternative. However, there has been relatively few approaches available in the literature for point or interval estimation of the crossing time point. The problem of constructing confidence intervals for the first crossing time point of two hazard functions is considered in this paper. After reviewing a recent procedure based on Cox proportional hazard modeling with Box-Cox transformation of the time to event, a nonparametric procedure using the kernel smoothing estimate of the hazard ratio is proposed. The proposed procedure and the one based on Cox proportional hazard modeling with Box-Cox transformation of the time to event are both evaluated by Monte-Carlo simulations and applied to two clinical trial datasets.

  13. IR investigation on silicon oxycarbide structure obtained from precursors with 1:1 silicon to carbon atoms ratio and various carbon atoms distribution

    NASA Astrophysics Data System (ADS)

    Niemiec, Wiktor; Szczygieł, Przemysław; Jeleń, Piotr; Handke, Mirosław

    2018-07-01

    Silicon oxycarbide is a material with a number of advantageous properties that strongly depend on its structure. The most common approach to its tailoring is based on varying the silicon to carbon atoms ratio in the preceramic polymeric precursor. This work is the first comparison of the materials obtained from precursors with the same Si to C atoms ratio, but with various distribution of these atoms in the preceramic polymer. In addition to standard mixtures of monomers containing single silicon atom, a number of monomers with high molar masses and well defined structure was used. The IR was used to investigate the structure of the precursors and materials obtained after their annealing in 800 °C. The results show, that not only the distribution of carbon containing groups among the monomers is important, but also the (in)ability of these groups to end up in each other vicinity in the precursor as well as the degree of condensation of each structural unit.

  14. Quantifying the relative risk of sex offenders: risk ratios for static-99R.

    PubMed

    Hanson, R Karl; Babchishin, Kelly M; Helmus, Leslie; Thornton, David

    2013-10-01

    Given the widespread use of empirical actuarial risk tools in corrections and forensic mental health, it is important that evaluators and decision makers understand how scores relate to recidivism risk. In the current study, we found strong evidence for a relative risk interpretation of Static-99R scores using 8 samples from Canada, United Kingdom, and Western Europe (N = 4,037 sex offenders). Each increase in Static-99R score was associated with a stable and consistent increase in relative risk (as measured by an odds ratio or hazard ratio of approximately 1.4). Hazard ratios from Cox regression were used to calculate risk ratios that can be reported for Static-99R. We recommend that evaluators consider risk ratios as a useful, nonarbitrary metric for quantifying and communicating risk information. To avoid misinterpretation, however, risk ratios should be presented with recidivism base rates.

  15. Flight loads measurements obtained from calibrated strain-gage bridges mounted externally on the skin of a low-aspect-ratio wing

    NASA Technical Reports Server (NTRS)

    Eckstrom, C. V.

    1976-01-01

    Flight-test measurements of wingloads (shear, bending moment, and torque) were obtained by means of strain-gage bridges mounted on the exterior surface of a low-aspect-ratio, thin, swept wing which had a structural skin, full-depth honeycomb core, sandwich construction. Details concerning the strain-gage bridges, the calibration procedures used, and the flight-test results are presented along with some pressure measurements and theoretical calculations for comparison purposes.

  16. NASA Hydrogen Peroxide Propellant Hazards Technical Manual

    NASA Technical Reports Server (NTRS)

    Baker, David L.; Greene, Ben; Frazier, Wayne

    2005-01-01

    The Fire, Explosion, Compatibility and Safety Hazards of Hydrogen Peroxide NASA technical manual was developed at the NASA Johnson Space Center White Sands Test Facility. NASA Technical Memorandum TM-2004-213151 covers topics concerning high concentration hydrogen peroxide including fire and explosion hazards, material and fluid reactivity, materials selection information, personnel and environmental hazards, physical and chemical properties, analytical spectroscopy, specifications, analytical methods, and material compatibility data. A summary of hydrogen peroxide-related accidents, incidents, dose calls, mishaps and lessons learned is included. The manual draws from art extensive literature base and includes recent applicable regulatory compliance documentation. The manual may be obtained by United States government agencies from NASA Johnson Space Center and used as a reference source for hazards and safe handling of hydrogen peroxide.

  17. National information network and database system of hazardous waste management in China

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ma Hongchang

    1996-12-31

    Industries in China generate large volumes of hazardous waste, which makes it essential for the nation to pay more attention to hazardous waste management. National laws and regulations, waste surveys, and manifest tracking and permission systems have been initiated. Some centralized hazardous waste disposal facilities are under construction. China`s National Environmental Protection Agency (NEPA) has also obtained valuable information on hazardous waste management from developed countries. To effectively share this information with local environmental protection bureaus, NEPA developed a national information network and database system for hazardous waste management. This information network will have such functions as information collection, inquiry,more » and connection. The long-term objective is to establish and develop a national and local hazardous waste management information network. This network will significantly help decision makers and researchers because it will be easy to obtain information (e.g., experiences of developed countries in hazardous waste management) to enhance hazardous waste management in China. The information network consists of five parts: technology consulting, import-export management, regulation inquiry, waste survey, and literature inquiry.« less

  18. Landslide susceptibility mapping by combining the three methods Fuzzy Logic, Frequency Ratio and Analytical Hierarchy Process in Dozain basin

    NASA Astrophysics Data System (ADS)

    Tazik, E.; Jahantab, Z.; Bakhtiari, M.; Rezaei, A.; Kazem Alavipanah, S.

    2014-10-01

    Landslides are among the most important natural hazards that lead to modification of the environment. Therefore, studying of this phenomenon is so important in many areas. Because of the climate conditions, geologic, and geomorphologic characteristics of the region, the purpose of this study was landslide hazard assessment using Fuzzy Logic, frequency ratio and Analytical Hierarchy Process method in Dozein basin, Iran. At first, landslides occurred in Dozein basin were identified using aerial photos and field studies. The influenced landslide parameters that were used in this study including slope, aspect, elevation, lithology, precipitation, land cover, distance from fault, distance from road and distance from river were obtained from different sources and maps. Using these factors and the identified landslide, the fuzzy membership values were calculated by frequency ratio. Then to account for the importance of each of the factors in the landslide susceptibility, weights of each factor were determined based on questionnaire and AHP method. Finally, fuzzy map of each factor was multiplied to its weight that obtained using AHP method. At the end, for computing prediction accuracy, the produced map was verified by comparing to existing landslide locations. These results indicate that the combining the three methods Fuzzy Logic, Frequency Ratio and Analytical Hierarchy Process method are relatively good estimators of landslide susceptibility in the study area. According to landslide susceptibility map about 51% of the occurred landslide fall into the high and very high susceptibility zones of the landslide susceptibility map, but approximately 26 % of them indeed located in the low and very low susceptibility zones.

  19. [Relations of landslide and debris flow hazards to environmental factors].

    PubMed

    Zhang, Guo-ping; Xu, Jing; Bi, Bao-gui

    2009-03-01

    To clarify the relations of landslide and debris flow hazards to environmental factors is of significance to the prediction and evaluation of landslide and debris flow hazards. Base on the latitudinal and longitudinal information of 18431 landslide and debris flow hazards in China, and the 1 km x 1 km grid data of elevation, elevation difference, slope, slope aspect, vegetation type, and vegetation coverage, this paper analyzed the relations of landslide and debris flow hazards in this country to above-mentioned environmental factors by the analysis method of frequency ratio. The results showed that the landslide and debris flow hazards in China more occurred in lower elevation areas of the first and second transitional zones. When the elevation difference within a 1 km x 1 km grid cell was about 300 m and the slope was around 30 degree, there was the greatest possibility of the occurrence of landslide and debris hazards. Mountain forest land and slope cropland were the two land types the hazards most easily occurred. The occurrence frequency of the hazards was the highest when the vegetation coverage was about 80%-90%.

  20. Identification of cardiometabolic risk: visceral adiposity index versus triglyceride/HDL cholesterol ratio.

    PubMed

    Salazar, Martin R; Carbajal, Horacio A; Espeche, Walter G; Aizpurúa, Marcelo; Maciel, Pablo M; Reaven, Gerald M

    2014-02-01

    The plasma concentration ratio of triglyceride (TG)/high-density lipoprotein cholesterol (HDL-C) can identify cardiometabolic risk and cardiovascular disease. The visceral adiposity index is a sex-specific index, in which measurements of body mass index and waist circumference are combined with TG and HDL-C concentrations. The current analysis was initiated to see if the visceral adiposity index would improve the ability of the TG/HDL-C to identify increased cardiometabolic risk and outcome. Cardiometabolic data were obtained in 2003 from 926 apparently healthy individuals, 796 of whom were evaluated in 2012 for evidence of incident cardiovascular disease. The relationship between TG/HDL-C and values for visceral adiposity index was evaluated by Pearson's correlation coefficient. The relative risks for first cardiovascular event between individuals above and below the TG/HDL-C sex-specific cut points, and in the top quartile of visceral adiposity index versus the remaining 3 quartiles, were estimated using Cox proportional hazard models. TG/HDL-C concentration and visceral adiposity index were highly correlated (r = 0.99) in both men and women. Although more men (133 vs121) and women (73 vs 59) were identified as being at "high risk" by an elevated TG/HDL-C ratio, the individual cardiometabolic risk factors were essentially identical with either index used. However, the hazard ratio of developing cardiovascular disease was significantly increased in individuals with an elevated TG/HDL-C, whereas it was not the case when the visceral adiposity index was used to define "high risk." The visceral adiposity index does not identify individuals with an adverse cardiometabolic profile any better than the TG/HDL-C. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Association between stricter alcohol advertising regulations and lower hazardous drinking across European countries.

    PubMed

    Bosque-Prous, Marina; Espelt, Albert; Guitart, Anna M; Bartroli, Montserrat; Villalbí, Joan R; Brugal, M Teresa

    2014-10-01

    To analyse the association between alcohol advertising restrictions and the prevalence of hazardous drinking among people aged 50-64 years in 16 European countries, taking into account both individual and contextual-level factors (alcohol taxation, availability, etc.). Cross-sectional study based on SHARE project surveys. A total of 27 773 subjects, aged 50-64 years, from 16 European countries who participated in wave 4 of the SHARE (Survey of Health, Ageing and Retirement in Europe) project. We estimated the prevalence of hazardous drinking (through adaptation of the SHARE questions to the scheme used by the Alcohol Use Disorders Identification Test Consumption (AUDIT-C) for each country. To determine whether the degree of advertising restrictions was associated with prevalence of hazardous drinking, we fitted robust variance multi-level Poisson models, adjusting for various individual and contextual variables. Prevalence ratios (PR) and their 95% confidence intervals (95% CI) were obtained. The observed prevalence of hazardous drinking was 24.1%, varying by sex and country. Countries with greater advertising restrictions had lower prevalence of hazardous drinking: 30.6% (95% CI = 29.3-31.8) in countries with no restrictions, 20.3% (95% CI = 19.3-21.2) in countries with some restrictions and 14.4% (95% CI = 11.9-16.8) in those with greatest restrictions. The PR found (with respect to countries with greatest restrictions) were 1.36 (95% CI = 0.90-2.06) for countries with some restrictions and 1.95 (95% CI = 1.31-2.91) for those with no advertising restrictions. The extent of advertising restrictions in European countries is associated inversely with prevalence of hazardous drinking in people aged 50-64 years. © 2014 Society for the Study of Addiction.

  2. LAV@HAZARD: a Web-GIS Framework for Real-Time Forecasting of Lava Flow Hazards

    NASA Astrophysics Data System (ADS)

    Del Negro, C.; Bilotta, G.; Cappello, A.; Ganci, G.; Herault, A.

    2014-12-01

    Crucial to lava flow hazard assessment is the development of tools for real-time prediction of flow paths, flow advance rates, and final flow lengths. Accurate prediction of flow paths and advance rates requires not only rapid assessment of eruption conditions (especially effusion rate) but also improved models of lava flow emplacement. Here we present the LAV@HAZARD web-GIS framework, which combines spaceborne remote sensing techniques and numerical simulations for real-time forecasting of lava flow hazards. By using satellite-derived discharge rates to drive a lava flow emplacement model, LAV@HAZARD allows timely definition of parameters and maps essential for hazard assessment, including the propagation time of lava flows and the maximum run-out distance. We take advantage of the flexibility of the HOTSAT thermal monitoring system to process satellite images coming from sensors with different spatial, temporal and spectral resolutions. HOTSAT was designed to ingest infrared satellite data acquired by the MODIS and SEVIRI sensors to output hot spot location, lava thermal flux and discharge rate. We use LAV@HAZARD to merge this output with the MAGFLOW physics-based model to simulate lava flow paths and to update, in a timely manner, flow simulations. Thus, any significant changes in lava discharge rate are included in the predictions. A significant benefit in terms of computational speed was obtained thanks to the parallel implementation of MAGFLOW on graphic processing units (GPUs). All this useful information has been gathered into the LAV@HAZARD platform which, due to the high degree of interactivity, allows generation of easily readable maps and a fast way to explore alternative scenarios. We will describe and demonstrate the operation of this framework using a variety of case studies pertaining to Mt Etna, Sicily. Although this study was conducted on Mt Etna, the approach used is designed to be applicable to other volcanic areas around the world.

  3. Hazardous Waste: Learn the Basics of Hazardous Waste

    MedlinePlus

    ... to set up a framework for the proper management of hazardous waste. Need More Information on Hazardous Waste? The RCRA Orientation Manual provides ... facility management standards, specific provisions governing hazardous waste management units ... information on the final steps in EPA’s hazardous waste ...

  4. Landslide Hazard from Coupled Inherent and Dynamic Probabilities

    NASA Astrophysics Data System (ADS)

    Strauch, R. L.; Istanbulluoglu, E.; Nudurupati, S. S.

    2015-12-01

    Landslide hazard research has typically been conducted independently from hydroclimate research. We sought to unify these two lines of research to provide regional scale landslide hazard information for risk assessments and resource management decision-making. Our approach couples an empirical inherent landslide probability, based on a frequency ratio analysis, with a numerical dynamic probability, generated by combining subsurface water recharge and surface runoff from the Variable Infiltration Capacity (VIC) macro-scale land surface hydrologic model with a finer resolution probabilistic slope stability model. Landslide hazard mapping is advanced by combining static and dynamic models of stability into a probabilistic measure of geohazard prediction in both space and time. This work will aid resource management decision-making in current and future landscape and climatic conditions. The approach is applied as a case study in North Cascade National Park Complex in northern Washington State.

  5. Volcanic hazard management in dispersed volcanism areas

    NASA Astrophysics Data System (ADS)

    Marrero, Jose Manuel; Garcia, Alicia; Ortiz, Ramon

    2014-05-01

    Traditional volcanic hazard methodologies were developed mainly to deal with the big stratovolcanoes. In such type of volcanoes, the hazard map is an important tool for decision-makers not only during a volcanic crisis but also for territorial planning. According to the past and recent eruptions of a volcano, all possible volcanic hazards are modelled and included in the hazard map. Combining the hazard map with the Event Tree the impact area can be zoned and defining the likely eruptive scenarios that will be used during a real volcanic crisis. But in areas of disperse volcanism is very complex to apply the same volcanic hazard methodologies. The event tree do not take into account unknown vents, because the spatial concepts included in it are only related with the distance reached by volcanic hazards. The volcanic hazard simulation is also difficult because the vent scatter modifies the results. The volcanic susceptibility try to solve this problem, calculating the most likely areas to have an eruption, but the differences between low and large values obtained are often very small. In these conditions the traditional hazard map effectiveness could be questioned, making necessary a change in the concept of hazard map. Instead to delimit the potential impact areas, the hazard map should show the expected behaviour of the volcanic activity and how the differences in the landscape and internal geo-structures could condition such behaviour. This approach has been carried out in La Palma (Canary Islands), combining the concept of long-term hazard map with the short-term volcanic scenario to show the expected volcanic activity behaviour. The objective is the decision-makers understand how a volcanic crisis could be and what kind of mitigation measurement and strategy could be used.

  6. Transportation of Hazardous Materials Emergency Preparedness Hazards Assessment

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Blanchard, A.

    This report documents the Emergency Preparedness Hazards Assessment (EPHA) for the Transportation of Hazardous Materials (THM) at the Department of Energy (DOE) Savannah River Site (SRS). This hazards assessment is intended to identify and analyze those transportation hazards significant enough to warrant consideration in the SRS Emergency Management Program.

  7. A novel hazard assessment method for biomass gasification stations based on extended set pair analysis

    PubMed Central

    Yan, Fang; Xu, Kaili; Li, Deshun; Cui, Zhikai

    2017-01-01

    Biomass gasification stations are facing many hazard factors, therefore, it is necessary to make hazard assessment for them. In this study, a novel hazard assessment method called extended set pair analysis (ESPA) is proposed based on set pair analysis (SPA). However, the calculation of the connection degree (CD) requires the classification of hazard grades and their corresponding thresholds using SPA for the hazard assessment. In regard to the hazard assessment using ESPA, a novel calculation algorithm of the CD is worked out when hazard grades and their corresponding thresholds are unknown. Then the CD can be converted into Euclidean distance (ED) by a simple and concise calculation, and the hazard of each sample will be ranked based on the value of ED. In this paper, six biomass gasification stations are introduced to make hazard assessment using ESPA and general set pair analysis (GSPA), respectively. By the comparison of hazard assessment results obtained from ESPA and GSPA, the availability and validity of ESPA can be proved in the hazard assessment for biomass gasification stations. Meanwhile, the reasonability of ESPA is also justified by the sensitivity analysis of hazard assessment results obtained by ESPA and GSPA. PMID:28938011

  8. Hazard function theory for nonstationary natural hazards

    NASA Astrophysics Data System (ADS)

    Read, L.; Vogel, R. M.

    2015-12-01

    Studies from the natural hazards literature indicate that many natural processes, including wind speeds, landslides, wildfires, precipitation, streamflow and earthquakes, show evidence of nonstationary behavior such as trends in magnitudes through time. Traditional probabilistic analysis of natural hazards based on partial duration series (PDS) generally assumes stationarity in the magnitudes and arrivals of events, i.e. that the probability of exceedance is constant through time. Given evidence of trends and the consequent expected growth in devastating impacts from natural hazards across the world, new methods are needed to characterize their probabilistic behavior. The field of hazard function analysis (HFA) is ideally suited to this problem because its primary goal is to describe changes in the exceedance probability of an event over time. HFA is widely used in medicine, manufacturing, actuarial statistics, reliability engineering, economics, and elsewhere. HFA provides a rich theory to relate the natural hazard event series (x) with its failure time series (t), enabling computation of corresponding average return periods and reliabilities associated with nonstationary event series. This work investigates the suitability of HFA to characterize nonstationary natural hazards whose PDS magnitudes are assumed to follow the widely applied Poisson-GP model. We derive a 2-parameter Generalized Pareto hazard model and demonstrate how metrics such as reliability and average return period are impacted by nonstationarity and discuss the implications for planning and design. Our theoretical analysis linking hazard event series x, with corresponding failure time series t, should have application to a wide class of natural hazards.

  9. Hazard function theory for nonstationary natural hazards

    NASA Astrophysics Data System (ADS)

    Read, Laura K.; Vogel, Richard M.

    2016-04-01

    Impact from natural hazards is a shared global problem that causes tremendous loss of life and property, economic cost, and damage to the environment. Increasingly, many natural processes show evidence of nonstationary behavior including wind speeds, landslides, wildfires, precipitation, streamflow, sea levels, and earthquakes. Traditional probabilistic analysis of natural hazards based on peaks over threshold (POT) generally assumes stationarity in the magnitudes and arrivals of events, i.e., that the probability of exceedance of some critical event is constant through time. Given increasing evidence of trends in natural hazards, new methods are needed to characterize their probabilistic behavior. The well-developed field of hazard function analysis (HFA) is ideally suited to this problem because its primary goal is to describe changes in the exceedance probability of an event over time. HFA is widely used in medicine, manufacturing, actuarial statistics, reliability engineering, economics, and elsewhere. HFA provides a rich theory to relate the natural hazard event series (X) with its failure time series (T), enabling computation of corresponding average return periods, risk, and reliabilities associated with nonstationary event series. This work investigates the suitability of HFA to characterize nonstationary natural hazards whose POT magnitudes are assumed to follow the widely applied generalized Pareto model. We derive the hazard function for this case and demonstrate how metrics such as reliability and average return period are impacted by nonstationarity and discuss the implications for planning and design. Our theoretical analysis linking hazard random variable X with corresponding failure time series T should have application to a wide class of natural hazards with opportunities for future extensions.

  10. A carbon CT system: how to obtain accurate stopping power ratio using a Bragg peak reduction technique

    NASA Astrophysics Data System (ADS)

    Lee, Sung Hyun; Sunaguchi, Naoki; Hirano, Yoshiyuki; Kano, Yosuke; Liu, Chang; Torikoshi, Masami; Ohno, Tatsuya; Nakano, Takashi; Kanai, Tatsuaki

    2018-02-01

    In this study, we investigate the performance of the Gunma University Heavy Ion Medical Center’s ion computed tomography (CT) system, which measures the residual range of a carbon-ion beam using a fluoroscopy screen, a charge-coupled-device camera, and a moving wedge absorber and collects CT reconstruction images from each projection angle. Each 2D image was obtained by changing the polymethyl methacrylate (PMMA) thickness, such that all images for one projection could be expressed as the depth distribution in PMMA. The residual range as a function of PMMA depth was related to the range in water through a calibration factor, which was determined by comparing the PMMA-equivalent thickness measured by the ion CT system to the water-equivalent thickness measured by a water column. Aluminium, graphite, PMMA, and five biological phantoms were placed in a sample holder, and the residual range for each was quantified simultaneously. A novel method of CT reconstruction to correct for the angular deflection of incident carbon ions in the heterogeneous region utilising the Bragg peak reduction (BPR) is also introduced in this paper, and its performance is compared with other methods present in the literature such as the decomposition and differential methods. Stopping power ratio values derived with the BPR method from carbon-ion CT images matched closely with the true water-equivalent length values obtained from the validation slab experiment.

  11. Utility of serum lipid ratios for predicting incident type 2 diabetes: the Isfahan Diabetes Prevention Study.

    PubMed

    Janghorbani, Mohsen; Amini, Masoud

    2016-09-01

    In this study, we evaluate the association between triglyceride to high-density lipoprotein cholesterol (TG/HDL) ratio and total cholesterol (TC) to HDL (TC/HDL) ratio and the risks of type 2 diabetes (T2D) in an Iranian high-risk population. We analysed 7-year follow-up data (n = 1771) in non-diabetic first-degree relatives of consecutive patients with T2D 30-70 years old. The primary outcome was the diagnosis of T2D based on repeated oral glucose tolerance tests. We used Cox proportional hazard models to estimate hazard ratio for incident T2D across tertiles of TG/HDL and TC/HDL ratios and plotted a receiver operating characteristic (ROC) curve to assess discrimination. The highest tertile of TG/HDL and TC/HDL ratios compared with the lowest tertile was not associated with T2D in age- and gender-adjusted models (HR 0.99, 95% CI: 0.88, 1.11 for TG/HDL ratio and 1.10, 95% CI: 0.97, 1.23 for TC/HDL ratio). Further adjustment for waist circumference or body mass index, fasting plasma glucose, and low-density lipoprotein cholesterol did not appreciably alter the hazard ratio compared with the age- and gender-adjusted model. The area under the ROC curve for TG/HDL ratio was 57.7% (95% CI: 54.0, 61.5) and for TC/HDL ratio was 55.1% (95% CI: 51.2, 59.0). TG/HDL and TC/HDL ratios were not robust predictors of T2D in high-risk individuals in Iran. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

  12. Modelling multi-hazard hurricane damages on an urbanized coast with a Bayesian Network approach

    USGS Publications Warehouse

    van Verseveld, H.C.W.; Van Dongeren, A. R.; Plant, Nathaniel G.; Jäger, W.S.; den Heijer, C.

    2015-01-01

    Hurricane flood impacts to residential buildings in coastal zones are caused by a number of hazards, such as inundation, overflow currents, erosion, and wave attack. However, traditional hurricane damage models typically make use of stage-damage functions, where the stage is related to flooding depth only. Moreover, these models are deterministic and do not consider the large amount of uncertainty associated with both the processes themselves and with the predictions. This uncertainty becomes increasingly important when multiple hazards (flooding, wave attack, erosion, etc.) are considered simultaneously. This paper focusses on establishing relationships between observed damage and multiple hazard indicators in order to make better probabilistic predictions. The concept consists of (1) determining Local Hazard Indicators (LHIs) from a hindcasted storm with use of a nearshore morphodynamic model, XBeach, and (2) coupling these LHIs and building characteristics to the observed damages. We chose a Bayesian Network approach in order to make this coupling and used the LHIs ‘Inundation depth’, ‘Flow velocity’, ‘Wave attack’, and ‘Scour depth’ to represent flooding, current, wave impacts, and erosion related hazards.The coupled hazard model was tested against four thousand damage observations from a case site at the Rockaway Peninsula, NY, that was impacted by Hurricane Sandy in late October, 2012. The model was able to accurately distinguish ‘Minor damage’ from all other outcomes 95% of the time and could distinguish areas that were affected by the storm, but not severely damaged, 68% of the time. For the most heavily damaged buildings (‘Major Damage’ and ‘Destroyed’), projections of the expected damage underestimated the observed damage. The model demonstrated that including multiple hazards doubled the prediction skill, with Log-Likelihood Ratio test (a measure of improved accuracy and reduction in uncertainty) scores between 0.02 and 0

  13. Hazard assessment of selenium to endangered razorback suckers (Xyrauchen texanus)

    USGS Publications Warehouse

    Hamilton, S.J.; Holley, K.M.; Buhl, K.J.

    2002-01-01

    A hazard assessment was conducted based on information derived from two reproduction studies conducted with endangered razorback suckers (Xyrauchen texanus) at three sites near Grand Junction, CO, USA. Selenium contamination of the upper and lower Colorado River basin has been documented in water, sediment, and biota in studies by US Department of the Interior agencies and academia. Concern has been raised that this selenium contamination may be adversely affecting endangered fish in the upper Colorado River basin. The reproduction studies with razorback suckers revealed that adults readily accumulated selenium in various tissues including eggs, and that 4.6 μg/g of selenium in food organisms caused increased mortality of larvae. The selenium hazard assessment protocol resulted in a moderate hazard at the Horsethief site and high hazards at the Adobe Creek and North Pond sites. The selenium hazard assessment was considered conservative because an on-site toxicity test with razorback sucker larvae using 4.6 μg/g selenium in zooplankton caused nearly complete mortality, in spite of the moderate hazard at Horsethief. Using the margin of uncertainty ratio also suggested a high hazard for effects on razorback suckers from selenium exposure. Both assessment approaches suggested that selenium in the upper Colorado River basin adversely affects the reproductive success of razorback suckers.

  14. Hazard assessment of selenium to endangered razorback suckers (Xyrauchen texanus).

    PubMed

    Hamilton, Steven J; Holley, Kathleen M; Buhl, Kevin J

    2002-05-27

    A hazard assessment was conducted based on information derived from two reproduction studies conducted with endangered razorback suckers (Xyrauchen texanus) at three sites near Grand Junction, CO, USA. Selenium contamination of the upper and lower Colorado River basin has been documented in water, sediment, and biota in studies by US Department of the Interior agencies and academia. Concern has been raised that this selenium contamination may be adversely affecting endangered fish in the upper Colorado River basin. The reproduction studies with razorback suckers revealed that adults readily accumulated selenium in various tissues including eggs, and that 4.6 microg/g of selenium in food organisms caused increased mortality of larvae. The selenium hazard assessment protocol resulted in a moderate hazard at the Horsethief site and high hazards at the Adobe Creek and North Pond sites. The selenium hazard assessment was considered conservative because an on-site toxicity test with razorback sucker larvae using 4.6 microg/g selenium in zooplankton caused nearly complete mortality, in spite of the moderate hazard at Horsethief. Using the margin of uncertainty ratio also suggested a high hazard for effects on razorback suckers from selenium exposure. Both assessment approaches suggested that selenium in the upper Colorado River basin adversely affects the reproductive success of razorback suckers.

  15. The Relative Severity of Single Hazards within a Multi-Hazard Framework

    NASA Astrophysics Data System (ADS)

    Gill, Joel C.; Malamud, Bruce D.

    2013-04-01

    Here we present a description of the relative severity of single hazards within a multi-hazard framework, compiled through examining, quantifying and ranking the extent to which individual hazards trigger or increase the probability of other hazards. Hazards are broken up into six major groupings (geophysical, hydrological, shallow earth processes, atmospheric, biophysical and space), with the interactions for 21 different hazard types examined. These interactions include both one primary hazard triggering a secondary hazard, and one primary hazard increasing the probability of a secondary hazard occurring. We identify, through a wide-ranging review of grey- and peer-review literature, >90 interactions. The number of hazard-type linkages are then summed for each hazard in terms of their influence (the number of times one hazard type triggers another type of hazard, or itself) and their sensitivity (the number of times one hazard type is triggered by other hazard types, or itself). The 21 different hazards are then ranked based on (i) influence and (ii) sensitivity. We found, by quantification and ranking of these hazards, that: (i) The strongest influencers (those triggering the most secondary hazards) are volcanic eruptions, earthquakes and storms, which when taken together trigger almost a third of the possible hazard interactions identified; (ii) The most sensitive hazards (those being triggered by the most primary hazards) are identified to be landslides, volcanic eruptions and floods; (iii) When sensitivity rankings are adjusted to take into account the differential likelihoods of different secondary hazards being triggered, the most sensitive hazards are found to be landslides, floods, earthquakes and ground heave. We believe that by determining the strongest influencing and the most sensitive hazards for specific spatial areas, the allocation of resources for mitigation measures might be done more effectively.

  16. Hazard function theory for nonstationary natural hazards

    DOE PAGES

    Read, Laura K.; Vogel, Richard M.

    2016-04-11

    Impact from natural hazards is a shared global problem that causes tremendous loss of life and property, economic cost, and damage to the environment. Increasingly, many natural processes show evidence of nonstationary behavior including wind speeds, landslides, wildfires, precipitation, streamflow, sea levels, and earthquakes. Traditional probabilistic analysis of natural hazards based on peaks over threshold (POT) generally assumes stationarity in the magnitudes and arrivals of events, i.e., that the probability of exceedance of some critical event is constant through time. Given increasing evidence of trends in natural hazards, new methods are needed to characterize their probabilistic behavior. The well-developed field ofmore » hazard function analysis (HFA) is ideally suited to this problem because its primary goal is to describe changes in the exceedance probability of an event over time. HFA is widely used in medicine, manufacturing, actuarial statistics, reliability engineering, economics, and elsewhere. HFA provides a rich theory to relate the natural hazard event series ( X) with its failure time series ( T), enabling computation of corresponding average return periods, risk, and reliabilities associated with nonstationary event series. This work investigates the suitability of HFA to characterize nonstationary natural hazards whose POT magnitudes are assumed to follow the widely applied generalized Pareto model. We derive the hazard function for this case and demonstrate how metrics such as reliability and average return period are impacted by nonstationarity and discuss the implications for planning and design. As a result, our theoretical analysis linking hazard random variable  X with corresponding failure time series  T should have application to a wide class of natural hazards with opportunities for future extensions.« less

  17. Hazard function theory for nonstationary natural hazards

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Read, Laura K.; Vogel, Richard M.

    Impact from natural hazards is a shared global problem that causes tremendous loss of life and property, economic cost, and damage to the environment. Increasingly, many natural processes show evidence of nonstationary behavior including wind speeds, landslides, wildfires, precipitation, streamflow, sea levels, and earthquakes. Traditional probabilistic analysis of natural hazards based on peaks over threshold (POT) generally assumes stationarity in the magnitudes and arrivals of events, i.e., that the probability of exceedance of some critical event is constant through time. Given increasing evidence of trends in natural hazards, new methods are needed to characterize their probabilistic behavior. The well-developed field ofmore » hazard function analysis (HFA) is ideally suited to this problem because its primary goal is to describe changes in the exceedance probability of an event over time. HFA is widely used in medicine, manufacturing, actuarial statistics, reliability engineering, economics, and elsewhere. HFA provides a rich theory to relate the natural hazard event series ( X) with its failure time series ( T), enabling computation of corresponding average return periods, risk, and reliabilities associated with nonstationary event series. This work investigates the suitability of HFA to characterize nonstationary natural hazards whose POT magnitudes are assumed to follow the widely applied generalized Pareto model. We derive the hazard function for this case and demonstrate how metrics such as reliability and average return period are impacted by nonstationarity and discuss the implications for planning and design. As a result, our theoretical analysis linking hazard random variable  X with corresponding failure time series  T should have application to a wide class of natural hazards with opportunities for future extensions.« less

  18. Hazard function theory for nonstationary natural hazards

    NASA Astrophysics Data System (ADS)

    Read, L. K.; Vogel, R. M.

    2015-11-01

    Impact from natural hazards is a shared global problem that causes tremendous loss of life and property, economic cost, and damage to the environment. Increasingly, many natural processes show evidence of nonstationary behavior including wind speeds, landslides, wildfires, precipitation, streamflow, sea levels, and earthquakes. Traditional probabilistic analysis of natural hazards based on peaks over threshold (POT) generally assumes stationarity in the magnitudes and arrivals of events, i.e. that the probability of exceedance of some critical event is constant through time. Given increasing evidence of trends in natural hazards, new methods are needed to characterize their probabilistic behavior. The well-developed field of hazard function analysis (HFA) is ideally suited to this problem because its primary goal is to describe changes in the exceedance probability of an event over time. HFA is widely used in medicine, manufacturing, actuarial statistics, reliability engineering, economics, and elsewhere. HFA provides a rich theory to relate the natural hazard event series (X) with its failure time series (T), enabling computation of corresponding average return periods, risk and reliabilities associated with nonstationary event series. This work investigates the suitability of HFA to characterize nonstationary natural hazards whose POT magnitudes are assumed to follow the widely applied Generalized Pareto (GP) model. We derive the hazard function for this case and demonstrate how metrics such as reliability and average return period are impacted by nonstationarity and discuss the implications for planning and design. Our theoretical analysis linking hazard event series X, with corresponding failure time series T, should have application to a wide class of natural hazards with rich opportunities for future extensions.

  19. Aeromagnetic investigations of hazardous waste sites

    USGS Publications Warehouse

    ,

    1995-01-01

    Aeromagnetic survey data collected by helicopter over hazardous waste sites can be used to map the distribution of buried metallic (ferrous) objects at these sites, including drums and scrap metal. Thorough knowledge of the locations and nature of hazardous waste containers and contaminated objects is needed prior to the start of remediation efforts. Non-invasive geophysical techniques such as the aeromagnetic method provide the best way to obtain this knowledge. The U.S. Geological Survey (USGS) not only has experience in processing and interpreting aeromagnetic surveys of this type but also offers aid in the design and monitoring of contracts for such surveys.

  20. Hazard Interactions and Interaction Networks (Cascades) within Multi-Hazard Methodologies

    NASA Astrophysics Data System (ADS)

    Gill, Joel; Malamud, Bruce D.

    2016-04-01

    Here we combine research and commentary to reinforce the importance of integrating hazard interactions and interaction networks (cascades) into multi-hazard methodologies. We present a synthesis of the differences between 'multi-layer single hazard' approaches and 'multi-hazard' approaches that integrate such interactions. This synthesis suggests that ignoring interactions could distort management priorities, increase vulnerability to other spatially relevant hazards or underestimate disaster risk. We proceed to present an enhanced multi-hazard framework, through the following steps: (i) describe and define three groups (natural hazards, anthropogenic processes and technological hazards/disasters) as relevant components of a multi-hazard environment; (ii) outline three types of interaction relationship (triggering, increased probability, and catalysis/impedance); and (iii) assess the importance of networks of interactions (cascades) through case-study examples (based on literature, field observations and semi-structured interviews). We further propose visualisation frameworks to represent these networks of interactions. Our approach reinforces the importance of integrating interactions between natural hazards, anthropogenic processes and technological hazards/disasters into enhanced multi-hazard methodologies. Multi-hazard approaches support the holistic assessment of hazard potential, and consequently disaster risk. We conclude by describing three ways by which understanding networks of interactions contributes to the theoretical and practical understanding of hazards, disaster risk reduction and Earth system management. Understanding interactions and interaction networks helps us to better (i) model the observed reality of disaster events, (ii) constrain potential changes in physical and social vulnerability between successive hazards, and (iii) prioritise resource allocation for mitigation and disaster risk reduction.

  1. Natural hazard fatalities in Switzerland from 1946 to 2015

    NASA Astrophysics Data System (ADS)

    Badoux, Alexandre; Andres, Norina; Techel, Frank; Hegg, Christoph

    2016-12-01

    A database of fatalities caused by natural hazard processes in Switzerland was compiled for the period between 1946 and 2015. Using information from the Swiss flood and landslide damage database and the Swiss destructive avalanche database, the data set was extended back in time and more hazard processes were added by conducting an in-depth search of newspaper reports. The new database now covers all natural hazards common in Switzerland, categorised into seven process types: flood, landslide, rockfall, lightning, windstorm, avalanche and other processes (e.g. ice avalanches, earthquakes). Included were all fatal accidents associated with natural hazard processes in which victims did not expose themselves to an important danger on purpose. The database contains information on 635 natural hazard events causing 1023 fatalities, which corresponds to a mean of 14.6 victims per year. The most common causes of death were snow avalanches (37 %), followed by lightning (16 %), floods (12 %), windstorms (10 %), rockfall (8 %), landslides (7 %) and other processes (9 %). About 50 % of all victims died in one of the 507 single-fatality events; the other half were killed in the 128 multi-fatality events. The number of natural hazard fatalities that occurred annually during our 70-year study period ranged from 2 to 112 and exhibited a distinct decrease over time. While the number of victims in the first three decades (until 1975) ranged from 191 to 269 per decade, it ranged from 47 to 109 in the four following decades. This overall decrease was mainly driven by a considerable decline in the number of avalanche and lightning fatalities. About 75 % of victims were males in all natural hazard events considered together, and this ratio was roughly maintained in all individual process categories except landslides (lower) and other processes (higher). The ratio of male to female victims was most likely to be balanced when deaths occurred at home (in or near a building), a situation

  2. Mini-Sosie high-resolution seismic method aids hazards studies

    USGS Publications Warehouse

    Stephenson, W.J.; Odum, J.; Shedlock, K.M.; Pratt, T.L.; Williams, R.A.

    1992-01-01

    The Mini-Sosie high-resolution seismic method has been effective in imaging shallow-structure and stratigraphic features that aid in seismic-hazard and neotectonic studies. The method is not an alternative to Vibroseis acquisition for large-scale studies. However, it has two major advantages over Vibroseis as it is being used by the USGS in its seismic-hazards program. First, the sources are extremely portable and can be used in both rural and urban environments. Second, the shifting-and-summation process during acquisition improves the signal-to-noise ratio and cancels out seismic noise sources such as cars and pedestrians. -from Authors

  3. Using strain rates to forecast seismic hazards

    USGS Publications Warehouse

    Evans, Eileen

    2017-01-01

    One essential component in forecasting seismic hazards is observing the gradual accumulation of tectonic strain accumulation along faults before this strain is suddenly released as earthquakes. Typically, seismic hazard models are based on geologic estimates of slip rates along faults and historical records of seismic activity, neither of which records actively accumulating strain. But this strain can be estimated by geodesy: the precise measurement of tiny position changes of Earth’s surface, obtained from GPS, interferometric synthetic aperture radar (InSAR), or a variety of other instruments.

  4. Hazard interactions and interaction networks (cascades) within multi-hazard methodologies

    NASA Astrophysics Data System (ADS)

    Gill, Joel C.; Malamud, Bruce D.

    2016-08-01

    This paper combines research and commentary to reinforce the importance of integrating hazard interactions and interaction networks (cascades) into multi-hazard methodologies. We present a synthesis of the differences between multi-layer single-hazard approaches and multi-hazard approaches that integrate such interactions. This synthesis suggests that ignoring interactions between important environmental and anthropogenic processes could distort management priorities, increase vulnerability to other spatially relevant hazards or underestimate disaster risk. In this paper we proceed to present an enhanced multi-hazard framework through the following steps: (i) description and definition of three groups (natural hazards, anthropogenic processes and technological hazards/disasters) as relevant components of a multi-hazard environment, (ii) outlining of three types of interaction relationship (triggering, increased probability, and catalysis/impedance), and (iii) assessment of the importance of networks of interactions (cascades) through case study examples (based on the literature, field observations and semi-structured interviews). We further propose two visualisation frameworks to represent these networks of interactions: hazard interaction matrices and hazard/process flow diagrams. Our approach reinforces the importance of integrating interactions between different aspects of the Earth system, together with human activity, into enhanced multi-hazard methodologies. Multi-hazard approaches support the holistic assessment of hazard potential and consequently disaster risk. We conclude by describing three ways by which understanding networks of interactions contributes to the theoretical and practical understanding of hazards, disaster risk reduction and Earth system management. Understanding interactions and interaction networks helps us to better (i) model the observed reality of disaster events, (ii) constrain potential changes in physical and social vulnerability

  5. A human health assessment of hazardous air pollutants in Portland, OR.

    PubMed

    Tam, B N; Neumann, C M

    2004-11-01

    Ambient air samples collected from five monitoring sites in Portland, OR during July 1999 to August 2000 were analyzed for 43 hazardous air pollutants (HAP). HAP concentrations were compared to carcinogenic and non-carcinogenic benchmark levels. Carcinogenic benchmark concentrations were set at a risk level of one-in-one-million (1x10(-6)). Hazard ratios of 1.0 were used when comparing HAP concentrations to non-carcinogenic benchmarks. Emission sources (point, area, and mobile) were identified and a cumulative cancer risk and total hazard index were calculated for HAPs exceeding these health benchmark levels. Seventeen HAPs exceeded a cancer risk level of 1x10(-6) at all five monitoring sites. Nineteen HAPs exceeded this level at one or more site. Carbon tetrachloride, 1,3-butadiene, formaldehyde, and 1,1,2,2-tetrachloroethane contributed more than 50% to the upper-bound lifetime cumulative cancer risk of 2.47x10(-4). Acrolein was the only non-carcinogenic HAP with hazard ratios that exceeded 1.0 at all five sites. Mobile sources contributed the greatest percentage (68%) of HAP emissions. Additional monitoring and health assessments for HAPs in Portland, OR are warranted, including addressing issues that may have overestimated or underestimated risks in this study. Abatement strategies for HAPs that exceeded health benchmarks should be implemented to reduce potential adverse health risks.

  6. Assessment of Three Flood Hazard Mapping Methods: A Case Study of Perlis

    NASA Astrophysics Data System (ADS)

    Azizat, Nazirah; Omar, Wan Mohd Sabki Wan

    2018-03-01

    Flood is a common natural disaster and also affect the all state in Malaysia. Regarding to Drainage and Irrigation Department (DID) in 2007, about 29, 270 km2 or 9 percent of region of the country is prone to flooding. Flood can be such devastating catastrophic which can effected to people, economy and environment. Flood hazard mapping can be used is an important part in flood assessment to define those high risk area prone to flooding. The purposes of this study are to prepare a flood hazard mapping in Perlis and to evaluate flood hazard using frequency ratio, statistical index and Poisson method. The six factors affecting the occurrence of flood including elevation, distance from the drainage network, rainfall, soil texture, geology and erosion were created using ArcGIS 10.1 software. Flood location map in this study has been generated based on flooded area in year 2010 from DID. These parameters and flood location map were analysed to prepare flood hazard mapping in representing the probability of flood area. The results of the analysis were verified using flood location data in year 2013, 2014, 2015. The comparison result showed statistical index method is better in prediction of flood area rather than frequency ratio and Poisson method.

  7. Uncertainty on shallow landslide hazard assessment: from field data to hazard mapping

    NASA Astrophysics Data System (ADS)

    Trefolini, Emanuele; Tolo, Silvia; Patelli, Eduardo; Broggi, Matteo; Disperati, Leonardo; Le Tuan, Hai

    2015-04-01

    Shallow landsliding that involve Hillslope Deposits (HD), the surficial soil that cover the bedrock, is an important process of erosion, transport and deposition of sediment along hillslopes. Despite Shallow landslides generally mobilize relatively small volume of material, they represent the most hazardous factor in mountain regions due to their high velocity and the common absence of warning signs. Moreover, increasing urbanization and likely climate change make shallow landslides a source of widespread risk, therefore the interest of scientific community about this process grown in the last three decades. One of the main aims of research projects involved on this topic, is to perform robust shallow landslides hazard assessment for wide areas (regional assessment), in order to support sustainable spatial planning. Currently, three main methodologies may be implemented to assess regional shallow landslides hazard: expert evaluation, probabilistic (or data mining) methods and physical models based methods. The aim of this work is evaluate the uncertainty of shallow landslides hazard assessment based on physical models taking into account spatial variables such as: geotechnical and hydrogeologic parameters as well as hillslope morphometry. To achieve this goal a wide dataset of geotechnical properties (shear strength, permeability, depth and unit weight) of HD was gathered by integrating field survey, in situ and laboratory tests. This spatial database was collected from a study area of about 350 km2 including different bedrock lithotypes and geomorphological features. The uncertainty associated to each step of the hazard assessment process (e.g. field data collection, regionalization of site specific information and numerical modelling of hillslope stability) was carefully characterized. The most appropriate probability density function (PDF) was chosen for each numerical variable and we assessed the uncertainty propagation on HD strength parameters obtained by

  8. Lifecycle Management of Hazardous Materials/ Hazardous Waste. Revision 1.

    DTIC Science & Technology

    1997-02-01

    1 WHAT YOU NEED TO KNOW ABOUT HAZARDOUS MATERIALS (HM) ....................... 1 PURCHASING HAZARDOUS MATERIALS...20 Figures 1 . Acquisition Flowchart .................................. 12 2. NRaD Hazardous Material Pre-Purchase Checklist ........ 13 3. NRaD...Hazardous Waste Profile Sheet (Part 111) .................. 18 Tables 1 . Class 1 Ozone Depleting Substances .................... 11 i INTRODUCTION This

  9. Lymphocyte-to-monocyte ratio is associated with survival in pembrolizumab-treated metastatic melanoma patients.

    PubMed

    Failing, Jarrett J; Yan, Yiyi; Porrata, Luis F; Markovic, Svetomir N

    2017-12-01

    The peripheral blood lymphocyte-to-monocyte ratio (LMR) has been associated with prognosis in many malignancies including metastatic melanoma. However, it has not been studied in patients treated with immune checkpoint inhibitors. In this study, we analyzed the baseline LMR with progression-free survival (PFS) and overall survival (OS) in metastatic melanoma patients treated with pembrolizumab. A total of 133 patients with metastatic melanoma treated with pembrolizumab were included in this retrospective study. LMR was calculated from pretherapy peripheral blood counts and the optimal cutoff value was determined by a receiver operator characteristic curve. PFS and OS were evaluated using the Kaplan-Meier method and multivariate Cox proportional hazard modeling. Patients with an LMR of at least 1.7 showed improved PFS (hazard ratio=0.55; 95% confidence interval: 0.34-0.92; P=0.024) and OS (hazard ratio=0.29; 95% confidence interval: 0.15-0.59; P=0.0007). The baseline LMR is associated with PFS and OS in metastatic melanoma patients treated with pembrolizumab, and could represent a convenient and cost-effective prognostic biomarker. Validation of these findings in an independent cohort is needed.

  10. Dietary Sodium to Potassium Ratio and Risk of Stroke in a Multiethnic Urban Population: The Northern Manhattan Study.

    PubMed

    Willey, Joshua; Gardener, Hannah; Cespedes, Sandino; Cheung, Ying K; Sacco, Ralph L; Elkind, Mitchell S V

    2017-11-01

    There is growing evidence that increased dietary sodium (Na) intake increases the risk of vascular diseases, including stroke, at least in part via an increase in blood pressure. Higher dietary potassium (K), seen with increased intake of fruits and vegetables, is associated with lower blood pressure. The goal of this study was to determine the association of a dietary Na:K with risk of stroke in a multiethnic urban population. Stroke-free participants from the Northern Manhattan Study, a population-based cohort study of stroke incidence, were followed-up for incident stroke. Baseline food frequency questionnaires were analyzed for Na and K intake. We estimated the hazard ratios and 95% confidence intervals for the association of Na:K with incident total stroke using multivariable Cox proportional hazards models. Among 2570 participants with dietary data (mean age, 69±10 years; 64% women; 21% white; 55% Hispanic; 24% black), the mean Na:K ratio was 1.22±0.43. Over a mean follow-up of 12 years, there were 274 strokes. In adjusted models, a higher Na:K ratio was associated with increased risk for stroke (hazard ratio, 1.6; 95% confidence interval, 1.2-2.1) and specifically ischemic stroke (hazard ratio, 1.6; 95% confidence interval, 1.2-2.1). Na:K intake is an independent predictor of stroke risk. Further studies are required to understand the joint effect of Na and K intake on risk of cardiovascular disease. © 2017 American Heart Association, Inc.

  11. Physically and psychologically hazardous jobs and mental health in Thailand

    PubMed Central

    Yiengprugsawan, Vasoontara; Strazdins, Lyndall; Lim, Lynette L.-Y.; Kelly, Matthew; Seubsman, Sam-ang; Sleigh, Adrian C.

    2015-01-01

    This paper investigates associations between hazardous jobs, mental health and wellbeing among Thai adults. In 2005, 87 134 distance-learning students from Sukhothai Thammathirat Open University completed a self-administered questionnaire; at the 2009 follow-up 60 569 again participated. Job characteristics were reported in 2005, psychological distress and life satisfaction were reported in both 2005 and 2009. We derived two composite variables grading psychologically and physically hazardous jobs and reported adjusted odds ratios (AOR) from multivariate logistic regressions. Analyses focused on cohort members in paid work: the total was 62 332 at 2005 baseline and 41 671 at 2009 follow-up. Cross-sectional AORs linking psychologically hazardous jobs to psychological distress ranged from 1.52 (one hazard) to 4.48 (four hazards) for males and a corresponding 1.34–3.76 for females. Similarly AORs for physically hazardous jobs were 1.75 (one hazard) to 2.76 (four or more hazards) for males and 1.70–3.19 for females. A similar magnitude of associations was found between psychologically adverse jobs and low life satisfaction (AORs of 1.34–4.34 among males and 1.18–3.63 among females). Longitudinal analyses confirm these cross-sectional relationships. Thus, significant dose–response associations were found linking hazardous job exposures in 2005 to mental health and wellbeing in 2009. The health impacts of psychologically and physically hazardous jobs in developed, Western countries are equally evident in transitioning Southeast Asian countries such as Thailand. Regulation and monitoring of work conditions will become increasingly important to the health and wellbeing of the Thai workforce. PMID:24218225

  12. Physically and psychologically hazardous jobs and mental health in Thailand.

    PubMed

    Yiengprugsawan, Vasoontara; Strazdins, Lyndall; Lim, Lynette L-Y; Kelly, Matthew; Seubsman, Sam-ang; Sleigh, Adrian C

    2015-09-01

    This paper investigates associations between hazardous jobs, mental health and wellbeing among Thai adults. In 2005, 87 134 distance-learning students from Sukhothai Thammathirat Open University completed a self-administered questionnaire; at the 2009 follow-up 60 569 again participated. Job characteristics were reported in 2005, psychological distress and life satisfaction were reported in both 2005 and 2009. We derived two composite variables grading psychologically and physically hazardous jobs and reported adjusted odds ratios (AOR) from multivariate logistic regressions. Analyses focused on cohort members in paid work: the total was 62 332 at 2005 baseline and 41 671 at 2009 follow-up. Cross-sectional AORs linking psychologically hazardous jobs to psychological distress ranged from 1.52 (one hazard) to 4.48 (four hazards) for males and a corresponding 1.34-3.76 for females. Similarly AORs for physically hazardous jobs were 1.75 (one hazard) to 2.76 (four or more hazards) for males and 1.70-3.19 for females. A similar magnitude of associations was found between psychologically adverse jobs and low life satisfaction (AORs of 1.34-4.34 among males and 1.18-3.63 among females). Longitudinal analyses confirm these cross-sectional relationships. Thus, significant dose-response associations were found linking hazardous job exposures in 2005 to mental health and wellbeing in 2009. The health impacts of psychologically and physically hazardous jobs in developed, Western countries are equally evident in transitioning Southeast Asian countries such as Thailand. Regulation and monitoring of work conditions will become increasingly important to the health and wellbeing of the Thai workforce. © The Author 2013. Published by Oxford University Press.

  13. Prevalence of hazardous exposures in veterinary practice

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wiggins, P.; Schenker, M.B.; Green, R.

    1989-01-01

    All female graduates of a major U.S. veterinary school were surveyed by mailed questionnaire to obtain details of work practice and hazard exposure during the most recent year worked and during all pregnancies. Exposure questions were based on previously implicated occupational hazards which included anesthetic gases, radiation, zoonoses, prostaglandins, vaccines, physical trauma, and pesticides. The response rate was 86% (462/537). We found that practice type and pregnancy status were major determinants of hazard exposure within the veterinary profession. Small-animal practitioners reported the highest rates of exposure to anesthetic gas (94%), X-ray (90%), and pesticides (57%). Large-animal practitioners reported greater ratesmore » of trauma (64%) and potential exposure to prostaglandins (92%), Brucella abortus vaccine (23%), and carbon monoxide (18%). Potentially hazardous workplace practices or equipment were common. Forty-one percent of respondents who reported taking X-rays did not wear film badges, and 76% reported physically restraining animals for X-ray procedures. Twenty-seven percent of the respondents exposed to anesthetic gases worked at facilities which did not have waste anesthetic gas scavenging systems. Women who worked as veterinarians during a pregnancy attempted to reduce exposures to X-rays, insecticides, and other potentially hazardous exposures. Some potentially hazardous workplace exposures are common in veterinary practice, and measures to educate workers and to reduce these exposures should not await demonstration of adverse health effects.« less

  14. Modeling of Marine Natural Hazards in the Lesser Antilles

    NASA Astrophysics Data System (ADS)

    Zahibo, Narcisse; Nikolkina, Irina; Pelinovsky, Efim

    2010-05-01

    The Caribbean Sea countries are often affected by various marine natural hazards: hurricanes and cyclones, tsunamis and flooding. The historical data of marine natural hazards for the Lesser Antilles and specially, for Guadeloupe are presented briefly. Numerical simulation of several historical tsunamis in the Caribbean Sea (1755 Lisbon trans-Atlantic tsunami, 1867 Virgin Island earthquake tsunami, 2003 Montserrat volcano tsunami) are performed within the framework of the nonlinear-shallow theory. Numerical results demonstrate the importance of the real bathymetry variability with respect to the direction of propagation of tsunami wave and its characteristics. The prognostic tsunami wave height distribution along the Caribbean Coast is computed using various forms of seismic and hydrodynamics sources. These results are used to estimate the far-field potential for tsunami hazards at coastal locations in the Caribbean Sea. The nonlinear shallow-water theory is also applied to model storm surges induced by tropical cyclones, in particular, cyclones "Lilli" in 2002 and "Dean" in 2007. Obtained results are compared with observed data. The numerical models have been tested against known analytical solutions of the nonlinear shallow-water wave equations. Obtained results are described in details in [1-7]. References [1] N. Zahibo and E. Pelinovsky, Natural Hazards and Earth System Sciences, 1, 221 (2001). [2] N. Zahibo, E. Pelinovsky, A. Yalciner, A. Kurkin, A. Koselkov and A. Zaitsev, Oceanologica Acta, 26, 609 (2003). [3] N. Zahibo, E. Pelinovsky, A. Kurkin and A. Kozelkov, Science Tsunami Hazards. 21, 202 (2003). [4] E. Pelinovsky, N. Zahibo, P. Dunkley, M. Edmonds, R. Herd, T. Talipova, A. Kozelkov and I. Nikolkina, Science of Tsunami Hazards, 22, 44 (2004). [5] N. Zahibo, E. Pelinovsky, E. Okal, A. Yalciner, C. Kharif, T. Talipova and A. Kozelkov, Science of Tsunami Hazards, 23, 25 (2005). [6] N. Zahibo, E. Pelinovsky, T. Talipova, A. Rabinovich, A. Kurkin and I

  15. Ensemble of ground subsidence hazard maps using fuzzy logic

    NASA Astrophysics Data System (ADS)

    Park, Inhye; Lee, Jiyeong; Saro, Lee

    2014-06-01

    Hazard maps of ground subsidence around abandoned underground coal mines (AUCMs) in Samcheok, Korea, were constructed using fuzzy ensemble techniques and a geographical information system (GIS). To evaluate the factors related to ground subsidence, a spatial database was constructed from topographic, geologic, mine tunnel, land use, groundwater, and ground subsidence maps. Spatial data, topography, geology, and various ground-engineering data for the subsidence area were collected and compiled in a database for mapping ground-subsidence hazard (GSH). The subsidence area was randomly split 70/30 for training and validation of the models. The relationships between the detected ground-subsidence area and the factors were identified and quantified by frequency ratio (FR), logistic regression (LR) and artificial neural network (ANN) models. The relationships were used as factor ratings in the overlay analysis to create ground-subsidence hazard indexes and maps. The three GSH maps were then used as new input factors and integrated using fuzzy-ensemble methods to make better hazard maps. All of the hazard maps were validated by comparison with known subsidence areas that were not used directly in the analysis. As the result, the ensemble model was found to be more effective in terms of prediction accuracy than the individual model.

  16. Deterministic seismic hazard macrozonation of India

    NASA Astrophysics Data System (ADS)

    Kolathayar, Sreevalsa; Sitharam, T. G.; Vipin, K. S.

    2012-10-01

    Earthquakes are known to have occurred in Indian subcontinent from ancient times. This paper presents the results of seismic hazard analysis of India (6°-38°N and 68°-98°E) based on the deterministic approach using latest seismicity data (up to 2010). The hazard analysis was done using two different source models (linear sources and point sources) and 12 well recognized attenuation relations considering varied tectonic provinces in the region. The earthquake data obtained from different sources were homogenized and declustered and a total of 27,146 earthquakes of moment magnitude 4 and above were listed in the study area. The sesismotectonic map of the study area was prepared by considering the faults, lineaments and the shear zones which are associated with earthquakes of magnitude 4 and above. A new program was developed in MATLAB for smoothing of the point sources. For assessing the seismic hazard, the study area was divided into small grids of size 0.1° × 0.1° (approximately 10 × 10 km), and the hazard parameters were calculated at the center of each of these grid cells by considering all the seismic sources within a radius of 300 to 400 km. Rock level peak horizontal acceleration (PHA) and spectral accelerations for periods 0.1 and 1 s have been calculated for all the grid points with a deterministic approach using a code written in MATLAB. Epistemic uncertainty in hazard definition has been tackled within a logic-tree framework considering two types of sources and three attenuation models for each grid point. The hazard evaluation without logic tree approach also has been done for comparison of the results. The contour maps showing the spatial variation of hazard values are presented in the paper.

  17. An Analysis of Cumulative Risks Indicated by Biomonitoring Data of Six Phthalates Using the Maximum Cumulative Ratio

    EPA Science Inventory

    The Maximum Cumulative Ratio (MCR) quantifies the degree to which a single component of a chemical mixture drives the cumulative risk of a receptor.1 This study used the MCR, the Hazard Index (HI) and Hazard Quotient (HQ) to evaluate co-exposures to six phthalates using biomonito...

  18. Critical asset and portfolio risk analysis: an all-hazards framework.

    PubMed

    Ayyub, Bilal M; McGill, William L; Kaminskiy, Mark

    2007-08-01

    This article develops a quantitative all-hazards framework for critical asset and portfolio risk analysis (CAPRA) that considers both natural and human-caused hazards. Following a discussion on the nature of security threats, the need for actionable risk assessments, and the distinction between asset and portfolio-level analysis, a general formula for all-hazards risk analysis is obtained that resembles the traditional model based on the notional product of consequence, vulnerability, and threat, though with clear meanings assigned to each parameter. Furthermore, a simple portfolio consequence model is presented that yields first-order estimates of interdependency effects following a successful attack on an asset. Moreover, depending on the needs of the decisions being made and available analytical resources, values for the parameters in this model can be obtained at a high level or through detailed systems analysis. Several illustrative examples of the CAPRA methodology are provided.

  19. Treatment of hazardous waste landfill leachate using Fenton oxidation process

    NASA Astrophysics Data System (ADS)

    Singa, Pradeep Kumar; Hasnain Isa, Mohamed; Ho, Yeek-Chia; Lim, Jun-Wei

    2018-03-01

    The efficiency of Fenton's oxidation was assessed in this study for hazardous waste landfill leachate treatment. The two major reagents, which are generally employed in Fenton's process are H2O2 as oxidizing agent and Fe2+ as catalyst. Batch experiments were conducted to determine the effect of experimental conditions viz., reaction time, molar ratio, and Fenton reagent dosages, which are significant parameters that influence the degradation efficiencies of Fenton process were examined. It was found that under the favorable experimental conditions, maximum COD removal was 56.49%. The optimum experimental conditions were pH=3, H2O2/Fe2+ molar ratio = 3 and reaction time = 150 minutes. The optimal amount of hydrogen peroxide and iron were 0.12 mol/L and 0.04 mol/L respectively. High dosages of H2O2 and iron resulted in scavenging effects on OH• radicals and lowered degradation efficiency of organic compounds in the hazardous waste landfill leachate.

  20. Athletes and Sedentary Individuals: An Intergroup Comparison Utilizing a Pulmonary Function Ratio Obtained During Submaximal Exercise.

    ERIC Educational Resources Information Center

    Maud, Peter J.

    A pulmonary function ratio describing oxygen extraction from alveolar ventilation was used for an intergroup comparison between three groups of athletes (rugby, basketball, and football players) and one group of sedentary subjects during steady-state submaximal exercise. The ratio and its component parts are determined from only three gas…

  1. Probabilistic seismic hazard analysis (PSHA) for Ethiopia and the neighboring region

    NASA Astrophysics Data System (ADS)

    Ayele, Atalay

    2017-10-01

    Seismic hazard calculation is carried out for the Horn of Africa region (0°-20° N and 30°-50°E) based on the probabilistic seismic hazard analysis (PSHA) method. The earthquakes catalogue data obtained from different sources were compiled, homogenized to Mw magnitude scale and declustered to remove the dependent events as required by Poisson earthquake source model. The seismotectonic map of the study area that avails from recent studies is used for area sources zonation. For assessing the seismic hazard, the study area was divided into small grids of size 0.5° × 0.5°, and the hazard parameters were calculated at the center of each of these grid cells by considering contributions from all seismic sources. Peak Ground Acceleration (PGA) corresponding to 10% and 2% probability of exceedance in 50 years were calculated for all the grid points using generic rock site with Vs = 760 m/s. Obtained values vary from 0.0 to 0.18 g and 0.0-0.35 g for 475 and 2475 return periods, respectively. The corresponding contour maps showing the spatial variation of PGA values for the two return periods are presented here. Uniform hazard response spectrum (UHRS) for 10% and 2% probability of exceedance in 50 years and hazard curves for PGA and 0.2 s spectral acceleration (Sa) all at rock site are developed for the city of Addis Ababa. The hazard map of this study corresponding to the 475 return periods has already been used to update and produce the 3rd generation building code of Ethiopia.

  2. Spatial analysis of hazardous waste data using geostatistics

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zirschky, J.H.

    1984-01-01

    The objective of this investigation was to determine if geostatistics could be a useful tool for evaluating hazardous waste sites. Three sites contaminated by dioxin (2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)) were investigated. The first site evaluated was a creek into which TCDD-contaminated soil had eroded. The second site was a town in which TCDD-contaminated wastes had been sprayed onto the streets. Finally, the third site was a highway of which the shoulders were contaminated by dust deposition from a nearby hazardous waste site. The distribution of TCDD at the first and third sites were investigated using kriging, an optimal estimation technique. By usingmore » kriging, the areas of both sites requiring cleanup were successfully identified. At the second site, the town, satisfactory results were not obtained. The distribution of contamination in this town is believed to be very heterogeneous; thus, reasonable estimates could not be obtained. Additional sampling was therefore recommended at this site. Based upon this research, geostatistics appears to be a very useful tool for evaluating a hazardous waste site if the distribution of contaminants at the site is homogeneous, or can be divided into homogeneous areas.« less

  3. Landslide hazard mapping with selected dominant factors: A study case of Penang Island, Malaysia

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Tay, Lea Tien; Alkhasawneh, Mutasem Sh.; Ngah, Umi Kalthum

    Landslide is one of the destructive natural geohazards in Malaysia. In addition to rainfall as triggering factos for landslide in Malaysia, topographical and geological factors play important role in the landslide susceptibility analysis. Conventional topographic factors such as elevation, slope angle, slope aspect, plan curvature and profile curvature have been considered as landslide causative factors in many research works. However, other topographic factors such as diagonal length, surface area, surface roughness and rugosity have not been considered, especially for the research work in landslide hazard analysis in Malaysia. This paper presents landslide hazard mapping using Frequency Ratio (FR) and themore » study area is Penang Island of Malaysia. Frequency ratio approach is a variant of probabilistic method that is based on the observed relationships between the distribution of landslides and each landslide-causative factor. Landslide hazard map of Penang Island is produced by considering twenty-two (22) landslide causative factors. Among these twenty-two (22) factors, fourteen (14) factors are topographic factors. They are elevation, slope gradient, slope aspect, plan curvature, profile curvature, general curvature, tangential curvature, longitudinal curvature, cross section curvature, total curvature, diagonal length, surface area, surface roughness and rugosity. These topographic factors are extracted from the digital elevation model of Penang Island. The other eight (8) non-topographic factors considered are land cover, vegetation cover, distance from road, distance from stream, distance from fault line, geology, soil texture and rainfall precipitation. After considering all twenty-two factors for landslide hazard mapping, the analysis is repeated with fourteen dominant factors which are selected from the twenty-two factors. Landslide hazard map was segregated into four categories of risks, i.e. Highly hazardous area, Hazardous area, Moderately

  4. Hazards and hazard combinations relevant for the safety of nuclear power plants

    NASA Astrophysics Data System (ADS)

    Decker, Kurt; Brinkman, Hans; Raimond, Emmanuel

    2017-04-01

    The potential of the contemporaneous impact of different, yet causally related, hazardous events and event cascades on nuclear power plants is a major contributor to the overall risk of nuclear installations. In the aftermath of the Fukushima accident, which was caused by a combination of severe ground shaking by an earthquake, an earthquake-triggered tsunami and the disruption of the plants from the electrical grid by a seismically induced landslide, hazard combinations and hazard cascades moved into the focus of nuclear safety research. We therefore developed an exhaustive list of external hazards and hazard combinations which pose potential threats to nuclear installations in the framework of the European project ASAMPSAE (Advanced Safety Assessment: Extended PSA). The project gathers 31 partners from Europe, North Amerika and Japan. The list comprises of exhaustive lists of natural hazards, external man-made hazards, and a cross-correlation matrix of these hazards. The hazard list is regarded comprehensive by including all types of hazards that were previously cited in documents by IAEA, the Western European Nuclear Regulators Association (WENRA), and others. 73 natural hazards and 24 man-made external hazards are included. Natural hazards are grouped into seismotectonic hazards, flooding and hydrological hazards, extreme values of meteorological phenomena, rare meteorological phenomena, biological hazards / infestation, geological hazards, and forest fire / wild fire. The list of external man-made hazards includes industry accidents, military accidents, transportation accidents, pipeline accidents and other man-made external events. The large number of different hazards results in the extremely large number of 5.151 theoretically possible hazard combinations (not considering hazard cascades). In principle all of these combinations are possible to occur by random coincidence except for 82 hazard combinations that - depending on the time scale - are mutually

  5. Robust inference in discrete hazard models for randomized clinical trials.

    PubMed

    Nguyen, Vinh Q; Gillen, Daniel L

    2012-10-01

    Time-to-event data in which failures are only assessed at discrete time points are common in many clinical trials. Examples include oncology studies where events are observed through periodic screenings such as radiographic scans. When the survival endpoint is acknowledged to be discrete, common methods for the analysis of observed failure times include the discrete hazard models (e.g., the discrete-time proportional hazards and the continuation ratio model) and the proportional odds model. In this manuscript, we consider estimation of a marginal treatment effect in discrete hazard models where the constant treatment effect assumption is violated. We demonstrate that the estimator resulting from these discrete hazard models is consistent for a parameter that depends on the underlying censoring distribution. An estimator that removes the dependence on the censoring mechanism is proposed and its asymptotic distribution is derived. Basing inference on the proposed estimator allows for statistical inference that is scientifically meaningful and reproducible. Simulation is used to assess the performance of the presented methodology in finite samples.

  6. 12 CFR 760.6 - Required use of standard flood hazard determination form.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Required use of standard flood hazard determination form. 760.6 Section 760.6 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS..., computerized, or electronic manner. A credit union may obtain the standard flood hazard determination form from...

  7. 12 CFR 572.6 - Required use of standard flood hazard determination form.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 5 2011-01-01 2011-01-01 false Required use of standard flood hazard determination form. 572.6 Section 572.6 Banks and Banking OFFICE OF THRIFT SUPERVISION, DEPARTMENT OF THE..., computerized, or electronic manner. A savings association may obtain the standard flood hazard determination...

  8. Hazard Detection Analysis for a Forward-Looking Interferometer

    NASA Technical Reports Server (NTRS)

    West, Leanne; Gimmestad, Gary; Herkert, Ralph; Smith, William L.; Kireev, Stanislav; Schaffner, Philip R.; Daniels, Taumi S.; Cornman, Larry B.; Sharman, Robert; Weekley, Andrew; hide

    2010-01-01

    The Forward-Looking Interferometer (FLI) is a new instrument concept for obtaining the measurements required to alert flight crews to potential weather hazards to safe flight. To meet the needs of the commercial fleet, such a sensor should address multiple hazards to warrant the costs of development, certification, installation, training, and maintenance. The FLI concept is based on high-resolution Infrared Fourier Transform Spectrometry (FTS) technologies that have been developed for satellite remote sensing. These technologies have also been applied to the detection of aerosols and gases for other purposes. The FLI concept is being evaluated for its potential to address multiple hazards including clear air turbulence (CAT), volcanic ash, wake vortices, low slant range visibility, dry wind shear, and icing during all phases of flight (takeoff, cruise, and landing). The research accomplished in this second phase of the FLI project was in three major areas: further sensitivity studies to better understand the potential capabilities and requirements for an airborne FLI instrument, field measurements that were conducted in an effort to provide empirical demonstrations of radiometric hazard detection, and theoretical work to support the development of algorithms to determine the severity of detected hazards

  9. Probabilistic Seismic Hazard Assessment for Northeast India Region

    NASA Astrophysics Data System (ADS)

    Das, Ranjit; Sharma, M. L.; Wason, H. R.

    2016-08-01

    Northeast India bounded by latitudes 20°-30°N and longitudes 87°-98°E is one of the most seismically active areas in the world. This region has experienced several moderate-to-large-sized earthquakes, including the 12 June, 1897 Shillong earthquake ( M w 8.1) and the 15 August, 1950 Assam earthquake ( M w 8.7) which caused loss of human lives and significant damages to buildings highlighting the importance of seismic hazard assessment for the region. Probabilistic seismic hazard assessment of the region has been carried out using a unified moment magnitude catalog prepared by an improved General Orthogonal Regression methodology (Geophys J Int, 190:1091-1096, 2012; Probabilistic seismic hazard assessment of Northeast India region, Ph.D. Thesis, Department of Earthquake Engineering, IIT Roorkee, Roorkee, 2013) with events compiled from various databases (ISC, NEIC,GCMT, IMD) and other available catalogs. The study area has been subdivided into nine seismogenic source zones to account for local variation in tectonics and seismicity characteristics. The seismicity parameters are estimated for each of these source zones, which are input variables into seismic hazard estimation of a region. The seismic hazard analysis of the study region has been performed by dividing the area into grids of size 0.1° × 0.1°. Peak ground acceleration (PGA) and spectral acceleration ( S a) values (for periods of 0.2 and 1 s) have been evaluated at bedrock level corresponding to probability of exceedance (PE) of 50, 20, 10, 2 and 0.5 % in 50 years. These exceedance values correspond to return periods of 100, 225, 475, 2475, and 10,000 years, respectively. The seismic hazard maps have been prepared at the bedrock level, and it is observed that the seismic hazard estimates show a significant local variation in contrast to the uniform hazard value suggested by the Indian standard seismic code [Indian standard, criteria for earthquake-resistant design of structures, fifth edition, Part

  10. Probabilistic Seismic Hazard Assessment of the Chiapas State (SE Mexico)

    NASA Astrophysics Data System (ADS)

    Rodríguez-Lomelí, Anabel Georgina; García-Mayordomo, Julián

    2015-04-01

    The Chiapas State, in southeastern Mexico, is a very active seismic region due to the interaction of three tectonic plates: Northamerica, Cocos and Caribe. We present a probabilistic seismic hazard assessment (PSHA) specifically performed to evaluate seismic hazard in the Chiapas state. The PSHA was based on a composited seismic catalogue homogenized to Mw and was used a logic tree procedure for the consideration of different seismogenic source models and ground motion prediction equations (GMPEs). The results were obtained in terms of peak ground acceleration as well as spectral accelerations. The earthquake catalogue was compiled from the International Seismological Center and the Servicio Sismológico Nacional de México sources. Two different seismogenic source zones (SSZ) models were devised based on a revision of the tectonics of the region and the available geomorphological and geological maps. The SSZ were finally defined by the analysis of geophysical data, resulting two main different SSZ models. The Gutenberg-Richter parameters for each SSZ were calculated from the declustered and homogenized catalogue, while the maximum expected earthquake was assessed from both the catalogue and geological criteria. Several worldwide and regional GMPEs for subduction and crustal zones were revised. For each SSZ model we considered four possible combinations of GMPEs. Finally, hazard was calculated in terms of PGA and SA for 500-, 1000-, and 2500-years return periods for each branch of the logic tree using the CRISIS2007 software. The final hazard maps represent the mean values obtained from the two seismogenic and four attenuation models considered in the logic tree. For the three return periods analyzed, the maps locate the most hazardous areas in the Chiapas Central Pacific Zone, the Pacific Coastal Plain and in the Motagua and Polochic Fault Zone; intermediate hazard values in the Chiapas Batholith Zone and in the Strike-Slip Faults Province. The hazard decreases

  11. Identification of Potential Hazard using Hazard Identification and Risk Assessment

    NASA Astrophysics Data System (ADS)

    Sari, R. M.; Syahputri, K.; Rizkya, I.; Siregar, I.

    2017-03-01

    This research was conducted in the paper production’s company. These Paper products will be used as a cigarette paper. Along in the production’s process, Company provides the machines and equipment that operated by workers. During the operations, all workers may potentially injured. It known as a potential hazard. Hazard identification and risk assessment is one part of a safety and health program in the stage of risk management. This is very important as part of efforts to prevent occupational injuries and diseases resulting from work. This research is experiencing a problem that is not the identification of potential hazards and risks that would be faced by workers during the running production process. The purpose of this study was to identify the potential hazards by using hazard identification and risk assessment methods. Risk assessment is done using severity criteria and the probability of an accident. According to the research there are 23 potential hazard that occurs with varying severity and probability. Then made the determination Risk Assessment Code (RAC) for each potential hazard, and gained 3 extreme risks, 10 high risks, 6 medium risks and 3 low risks. We have successfully identified potential hazard using RAC.

  12. Occupational Hazard Exposures and Depressive Symptoms of Pregnant Workers.

    PubMed

    Yeh, Sherri S; Lee, Chien-Nan; Wu, Ying-Hsuan; Tu, Nai-Chi; Guo, Yue-Leon; Chen, Pau-Chung; Chen, Chi-Hsien

    2018-03-01

    The aim of this study was to explore the prevalence of exposure to occupational hazards and depressive mood with associated underlying risk factors among pregnant workers. Women at 12 weeks of gestation (n = 172) were recruited during regular prenatal screening. Data were obtained via questionnaires that explored job details and Edinburgh Postnatal Depression Scale. The most commonly encountered hazard was prolonged standing. The majority of women reported that the workplace provided no information on the safety or rights of pregnant women, but those exposed to at least four hazards had more access to such services (P < 0.05). Thirteen percent may have suffered from depressive symptomatology. Higher-level work-related burnout, lower job control, and reduced workplace support were significantly associated with possible antenatal depressive symptoms. Pregnant workers are exposed to substantial levels of occupational hazards and may experience depressive symptoms; thus, their work conditions require monitoring and improvement.

  13. Probabilistic seismic hazard assessment of southern part of Ghana

    NASA Astrophysics Data System (ADS)

    Ahulu, Sylvanus T.; Danuor, Sylvester Kojo; Asiedu, Daniel K.

    2018-05-01

    This paper presents a seismic hazard map for the southern part of Ghana prepared using the probabilistic approach, and seismic hazard assessment results for six cities. The seismic hazard map was prepared for 10% probability of exceedance for peak ground acceleration in 50 years. The input parameters used for the computations of hazard were obtained using data from a catalogue that was compiled and homogenised to moment magnitude (Mw). The catalogue covered a period of over a century (1615-2009). The hazard assessment is based on the Poisson model for earthquake occurrence, and hence, dependent events were identified and removed from the catalogue. The following attenuation relations were adopted and used in this study—Allen (for south and eastern Australia), Silva et al. (for Central and eastern North America), Campbell and Bozorgnia (for worldwide active-shallow-crust regions) and Chiou and Youngs (for worldwide active-shallow-crust regions). Logic-tree formalism was used to account for possible uncertainties associated with the attenuation relationships. OpenQuake software package was used for the hazard calculation. The highest level of seismic hazard is found in the Accra and Tema seismic zones, with estimated peak ground acceleration close to 0.2 g. The level of the seismic hazard in the southern part of Ghana diminishes with distance away from the Accra/Tema region to a value of 0.05 g at a distance of about 140 km.

  14. Landslide Hazards

    USGS Publications Warehouse

    ,

    2000-01-01

    Landslide hazards occur in many places around What Can You Do If You Live Near Steep Hills? the world and include fast-moving debris flows, slow-moving landslides, and a variety of flows and slides initiating from volcanoes. Each year, these hazards cost billions of dollars and cause numerous fatalities and injuries. Awareness and education about these hazards is a first step toward reducing damaging effects. The U.S. Geological Survey conducts research and distributes information about geologic hazards. This Fact Sheet is published in English and Spanish and can be reproduced in any form for further distribution. 

  15. High variable mixture ratio oxygen/hydrogen engine

    NASA Technical Reports Server (NTRS)

    Erickson, C. M.; Tu, W. H.; Weiss, A. H.

    1988-01-01

    The ability of an O2/H2 engine to operate over a range of high-propellant mixture ratios was previously shown to be advantageous in single stage to orbit (SSTO) vehicles. The results are presented for the analysis of high-performance engine power cycles operating over propellant mixture ratio ranges of 12 to 6 and 9 to 6. A requirement to throttle up to 60 percent of nominal thrust was superimposed as a typical throttle range to limit vehicle acceleration as propellant is expended. The object of the analysis was to determine areas of concern relative to component and engine operability or potential hazards resulting from the operating requirements and ranges of conditions that derive from the overall engine requirements. The SSTO mission necessitates a high-performance, lightweight engine. Therefore, staged combustion power cycles employing either dual fuel-rich preburners or dual mixed (fuel-rich and oxygen-rich) preburners were examined. Engine mass flow and power balances were made and major component operating ranges were defined. Component size and arrangement were determined through engine layouts for one of the configurations evaluated. Each component is being examined to determine if there are areas of concern with respect to component efficiency, operability, reliability, or hazard. The effects of reducing the maximum chamber pressure were investigated for one of the cycles.

  16. Time to achieving therapeutic international normalized ratio increases hospital length of stay after heart valve replacement surgery.

    PubMed

    Arendt, Christopher J; Hong, Joon Hwa; Daly, Richard C; Scott, Christopher; Mehta, Ramila A; Bailey, Kent; Pathak, Jyotishman; Pereira, Naveen L

    2017-05-01

    Achieving a therapeutic international normalized ratio (INR) before hospital discharge is an important inpatient goal for patients undergoing mechanical cardiac valve replacement (MCVR). The use of clinical algorithms has reduced the time to achieve therapeutic INR (TTI) with warfarin therapy. Whether TTI prolongs length of stay (LOS) is unknown. Patients who underwent MCVR over a consecutive 42-month period were included. Clinical data were obtained from the Society of Thoracic Surgeons Adult Cardiac Surgery database and electronic medical records. Therapeutic INR was defined as per standard guidelines. Warfarin dose was prescribed using an inpatient pharmacy-managed algorithm and computer-based dosing tool. International normalized ratio trajectory, procedural needs, and drug interactions were included in warfarin dose determination. There were 708 patients who underwent MCVR, of which 159 were excluded for reasons that would preclude or interrupt warfarin use. Among the remainder of 549 patients, the average LOS was 6.4days and mean TTI was 3.5days. Landmark analysis showed that subjects in hospital on day 4 (n=542) who achieved therapeutic INR were more likely to be discharged by day 6 compared with those who did not achieve therapeutic INR (75% vs 59%, P<.001). Multivariable proportional hazards regression with TTI as a time-dependent effect showed a strong association with discharge (P=.0096, hazard ratio1.3) after adjustment for other significant clinical covariates. Time to achieve therapeutic INR is an independent predictor of LOS in patients requiring anticoagulation with warfarin after MCVR surgery. Alternative dosing and anticoagulation strategies will need to be adopted to reduce LOS in these patients. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. 12 CFR 22.6 - Required use of standard flood hazard determination form.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 1 2011-01-01 2011-01-01 false Required use of standard flood hazard determination form. 22.6 Section 22.6 Banks and Banking COMPTROLLER OF THE CURRENCY, DEPARTMENT OF THE TREASURY... electronic manner. A bank may obtain the standard flood hazard determination form from FEMA, P.O. Box 2012...

  18. NASA Hazard Analysis Process

    NASA Technical Reports Server (NTRS)

    Deckert, George

    2010-01-01

    This viewgraph presentation reviews The NASA Hazard Analysis process. The contents include: 1) Significant Incidents and Close Calls in Human Spaceflight; 2) Subsystem Safety Engineering Through the Project Life Cycle; 3) The Risk Informed Design Process; 4) Types of NASA Hazard Analysis; 5) Preliminary Hazard Analysis (PHA); 6) Hazard Analysis Process; 7) Identify Hazardous Conditions; 8) Consider All Interfaces; 9) Work a Preliminary Hazard List; 10) NASA Generic Hazards List; and 11) Final Thoughts

  19. Earthquake Hazard Assessment: an Independent Review

    NASA Astrophysics Data System (ADS)

    Kossobokov, Vladimir

    2016-04-01

    Seismic hazard assessment (SHA), from term-less (probabilistic PSHA or deterministic DSHA) to time-dependent (t-DASH) including short-term earthquake forecast/prediction (StEF), is not an easy task that implies a delicate application of statistics to data of limited size and different accuracy. Regretfully, in many cases of SHA, t-DASH, and StEF, the claims of a high potential and efficiency of the methodology are based on a flawed application of statistics and hardly suitable for communication to decision makers. The necessity and possibility of applying the modified tools of Earthquake Prediction Strategies, in particular, the Error Diagram, introduced by G.M. Molchan in early 1990ies for evaluation of SHA, and the Seismic Roulette null-hypothesis as a measure of the alerted space, is evident, and such a testing must be done in advance claiming hazardous areas and/or times. The set of errors, i.e. the rates of failure and of the alerted space-time volume, compared to those obtained in the same number of random guess trials permits evaluating the SHA method effectiveness and determining the optimal choice of the parameters in regard to specified cost-benefit functions. These and other information obtained in such a testing may supply us with a realistic estimate of confidence in SHA results and related recommendations on the level of risks for decision making in regard to engineering design, insurance, and emergency management. These basics of SHA evaluation are exemplified with a few cases of misleading "seismic hazard maps", "precursors", and "forecast/prediction methods".

  20. Evaluation of seismic hazard at the northwestern part of Egypt

    NASA Astrophysics Data System (ADS)

    Ezzelarab, M.; Shokry, M. M. F.; Mohamed, A. M. E.; Helal, A. M. A.; Mohamed, Abuoelela A.; El-Hadidy, M. S.

    2016-01-01

    The objective of this study is to evaluate the seismic hazard at the northwestern Egypt using the probabilistic seismic hazard assessment approach. The Probabilistic approach was carried out based on a recent data set to take into account the historic seismicity and updated instrumental seismicity. A homogenous earthquake catalogue was compiled and a proposed seismic sources model was presented. The doubly-truncated exponential model was adopted for calculations of the recurrence parameters. Ground-motion prediction equations that recently recommended by experts and developed based upon earthquake data obtained from tectonic environments similar to those in and around the studied area were weighted and used for assessment of seismic hazard in the frame of logic tree approach. Considering a grid of 0.2° × 0.2° covering the study area, seismic hazard curves for every node were calculated. Hazard maps at bedrock conditions were produced for peak ground acceleration, in addition to six spectral periods (0.1, 0.2, 0.3, 1.0, 2.0 and 3.0 s) for return periods of 72, 475 and 2475 years. The unified hazard spectra of two selected rock sites at Alexandria and Mersa Matruh Cities were provided. Finally, the hazard curves were de-aggregated to determine the sources that contribute most of hazard level of 10% probability of exceedance in 50 years for the mentioned selected sites.

  1. The Role of Plasma Triglyceride/High-Density Lipoprotein Cholesterol Ratio to Predict New Cardiovascular Events in Essential Hypertensive Patients.

    PubMed

    Turak, Osman; Afşar, Barış; Ozcan, Fırat; Öksüz, Fatih; Mendi, Mehmet Ali; Yayla, Çagrı; Covic, Adrian; Bertelsen, Nathan; Kanbay, Mehmet

    2016-08-01

    Triglyceride (TG) to high-density lipoprotein cholesterol (HDL-C) ratio (TG/HDL-C) has been suggested as a simple method to identify unfavorable cardiovascular outcomes in the general population. The effect of the TG/HDL-C ratio on essential hypertensive patients is unclear. About 900 consecutive essential hypertensive patients (mean age 52.9±12.6 years, 54.2% male) who visited our outpatient hypertension clinic were analyzed. Participants were divided into quartiles based on baseline TG/HDL-C ratio and medical records were obtained periodically for the occurrence of fatal events and composite major adverse cardiovascular events (MACEs) including transient ischemic attack, stroke, aortic dissection, acute coronary syndrome, and death. Participants were followed for a median of 40 months (interquartile range, 35-44 months). Overall, a higher quartile of TG/HDL-C ratio at baseline was significantly linked with higher incidence of fatal and nonfatal cardiovascular events. Using multivariate Cox regression analysis, plasma TG/HDL-C ratio was independently associated with increased risk of fatal events (hazard ratio [HR], 1.25; 95% confidence interval [CI], 1.13-1.37; P≤.001] and MACEs (HR, 1.13; 95% CI, 1.06-1.21; P≤.001). Increased plasma TG/HDL-C ratio was associated with more fatal events and MACEs in essential hypertensive patients. © 2015 Wiley Periodicals, Inc.

  2. The influence of maximum magnitude on seismic-hazard estimates in the Central and Eastern United States

    USGS Publications Warehouse

    Mueller, C.S.

    2010-01-01

    I analyze the sensitivity of seismic-hazard estimates in the central and eastern United States (CEUS) to maximum magnitude (mmax) by exercising the U.S. Geological Survey (USGS) probabilistic hazard model with several mmax alternatives. Seismicity-based sources control the hazard in most of the CEUS, but data seldom provide an objective basis for estimating mmax. The USGS uses preferred mmax values of moment magnitude 7.0 and 7.5 for the CEUS craton and extended margin, respectively, derived from data in stable continental regions worldwide. Other approaches, for example analysis of local seismicity or judgment about a source's seismogenic potential, often lead to much smaller mmax. Alternative models span the mmax ranges from the 1980s Electric Power Research Institute/Seismicity Owners Group (EPRI/SOG) analysis. Results are presented as haz-ard ratios relative to the USGS national seismic hazard maps. One alternative model specifies mmax equal to moment magnitude 5.0 and 5.5 for the craton and margin, respectively, similar to EPRI/SOG for some sources. For 2% probability of exceedance in 50 years (about 0.0004 annual probability), the strong mmax truncation produces hazard ratios equal to 0.35-0.60 for 0.2-sec spectral acceleration, and 0.15-0.35 for 1.0-sec spectral acceleration. Hazard-controlling earthquakes interact with mmax in complex ways. There is a relatively weak dependence on probability level: hazardratios increase 0-15% for 0.002 annual exceedance probability and decrease 5-25% for 0.00001 annual exceedance probability. Although differences at some sites are tempered when faults are added, mmax clearly accounts for some of the discrepancies that are seen in comparisons between USGS-based and EPRI/SOG-based hazard results.

  3. Working towards a clearer and more helpful hazard map: investigating the influence of hazard map design on hazard communication

    NASA Astrophysics Data System (ADS)

    Thompson, M. A.; Lindsay, J. M.; Gaillard, J.

    2015-12-01

    Globally, geological hazards are communicated using maps. In traditional hazard mapping practice, scientists analyse data about a hazard, and then display the results on a map for stakeholder and public use. However, this one-way, top-down approach to hazard communication is not necessarily effective or reliable. The messages which people take away will be dependent on the way in which they read, interpret, and understand the map, a facet of hazard communication which has been relatively unexplored. Decades of cartographic studies suggest that variables in the visual representation of data on maps, such as colour and symbology, can have a powerful effect on how people understand map content. In practice, however, there is little guidance or consistency in how hazard information is expressed and represented on maps. Accordingly, decisions are often made based on subjective preference, rather than research-backed principles. Here we present the results of a study in which we explore how hazard map design features can influence hazard map interpretation, and we propose a number of considerations for hazard map design. A series of hazard maps were generated, with each one showing the same probabilistic volcanic ashfall dataset, but using different verbal and visual variables (e.g., different colour schemes, data classifications, probabilistic formats). Following a short pilot study, these maps were used in an online survey of 110 stakeholders and scientists in New Zealand. Participants answered 30 open-ended and multiple choice questions about ashfall hazard based on the different maps. Results suggest that hazard map design can have a significant influence on the messages readers take away. For example, diverging colour schemes were associated with concepts of "risk" and decision-making more than sequential schemes, and participants made more precise estimates of hazard with isarithmic data classifications compared to binned or gradational shading. Based on such

  4. Preoperative Platelet to Albumin Ratio Predicts Outcome of Patients with Cholangiocarcinoma.

    PubMed

    Saito, Nobuhiro; Shirai, Yoshihiro; Horiuchi, Takashi; Sugano, Hiroshi; Shiba, Hiroaki; Sakamoto, Taro; Uwagawa, Tadashi; Yanaga, Katsuhiko

    2018-02-01

    The purpose of this study was to evaluate the prognostic index of the preoperative platelet to albumin ratio (PAR) in patients who underwent primary resection for cholangiocarcinoma. A total of 59 patients were divided into two groups: those with PAR ≥72.6×10 3 or <72.6×10 3 according to the area under the receiver operating characteristics curve. PAR was significantly inversely associated with overall (OS) and disease-free (DFS) survival on univariate analysis. PAR showed significance on multivariate analysis for OS (hazard ratio=6.232, 95% confidence interval=1.283-30.279, p=0.023), along with tumor differentiation (p=0.009), nodal involvement (p=0.001), intraoperative blood loss (p=0.001), and serum carcinoembryonic antigen (CEA) (p=0.012). High PAR was also significantly associated poor DFS on multivariate analysis (hazard ratio(HR)=4.422, 95% confidence interval(CI)=1.168-16.732, p=0.029), along with tumor differentiation (p=0.009). PAR is a useful prognostic index for OS and DFS in patients with cholangiocarcinoma after primary resection. By accumulating cases prospectively, this new index may be a reference for use before neoadjuvant chemotherapy. Copyright© 2018, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  5. Mercury leaching from hazardous industrial wastes stabilized by sulfur polymer encapsulation.

    PubMed

    López, Félix A; Alguacil, Francisco J; Rodríguez, Olga; Sierra, María José; Millán, Rocío

    2015-01-01

    European Directive 2013/39/EU records mercury as a priority hazardous substance. Regulation n° 2008/1102/EC banned the exportation of mercury and required the safe storage of any remaining mercury compounds. The present work describes the encapsulation of three wastes containing combinations of HgS, HgSe, HgCl2, HgO2, Hg3Se2Cl2, HgO and Hg(0), according to patent of Spanish National Research Council WO2011/029970A2. The materials obtained were subjected to leaching tests according to standards UNE-EN-12457 and CEN/TS 14405:2004. The results are compared with the criteria established in the Council Decision 2003/33/EC for the acceptance of waste at landfills. The Hg concentrations of all leachates were <0.01mgHg/kg for a liquid/solid ratio of 10l/kg. All three encapsulated materials therefore meet the requirements for storage in inert waste landfills. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. 16 CFR 1500.231 - Guidance for hazardous liquid chemicals in children's products.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... hazardous chemicals, such as mercury, ethylene glycol, diethylene glycol, methanol, methylene chloride... purchasing products for resale, importers, distributors, and retailers obtain assurances from manufacturers... retailers obtain assurances from the manufacturers that liquid-filled children's products do not contain...

  7. Chemical incidents resulted in hazardous substances releases in the context of human health hazards.

    PubMed

    Pałaszewska-Tkacz, Anna; Czerczak, Sławomir; Konieczko, Katarzyna

    2017-02-21

    The research purpose was to analyze data concerning chemical incidents in Poland collected in 1999-2009 in terms of health hazards. The data was obtained, using multimodal information technology (IT) system, from chemical incidents reports prepared by rescuers at the scene. The final analysis covered sudden events associated with uncontrolled release of hazardous chemical substances or mixtures, which may potentially lead to human exposure. Releases of unidentified substances where emergency services took action to protect human health or environment were also included. The number of analyzed chemical incidents in 1999-2009 was 2930 with more than 200 different substances released. The substances were classified into 13 groups of substances and mixtures posing analogous risks. Most common releases were connected with non-flammable corrosive liquids, including: hydrochloric acid (199 cases), sulfuric(VI) acid (131 cases), sodium and potassium hydroxides (69 cases), ammonia solution (52 cases) and butyric acid (32 cases). The next group were gases hazardous only due to physico-chemical properties, including: extremely flammable propane-butane (249 cases) and methane (79 cases). There was no statistically significant trend associated with the total number of incidents. Only with the number of incidents with flammable corrosive, toxic and/or harmful liquids, the regression analysis revealed a statistically significant downward trend. The number of victims reported was 1997, including 1092 children and 18 fatalities. The number of people injured, number of incidents and the high 9th place of Poland in terms of the number of Seveso establishments, and 4 times higher number of hazardous industrial establishments not covered by the Seveso Directive justify the need for systematic analysis of hazards and their proper identification. It is advisable enhance health risk assessment, both qualitative and quantitative, by slight modification of the data collection system so as

  8. Study of Seismic Hazards in the Center of the State of Veracruz, MÉXICO.

    NASA Astrophysics Data System (ADS)

    Torres Morales, G. F.; Leonardo Suárez, M.; Dávalos Sotelo, R.; Mora González, I.; Castillo Aguilar, S.

    2015-12-01

    Preliminary results obtained from the project "Microzonation of geological and hydrometeorological hazards for conurbations of Orizaba, Veracruz, and major sites located in the lower sub-basins: The Antigua and Jamapa" are presented. These project was supported by the Joint Funds CONACyT-Veracruz state government. It was developed a probabilistic seismic hazard assessment (henceforth PSHA) in the central area of Veracruz State, mainly in a region bounded by the watersheds of the rivers Jamapa and Antigua, whit the aim to evaluate the geological and hydrometeorological hazards in this region. The project pays most attention to extreme weather phenomena, floods and earthquakes, in order to calculate the risk induced by previous for landslides and rock falls. In addition, as part of the study, the PSHA was developed considered the site effect in the urban zones of the cities Xalapa and Orizaba; the site effects were incorporated by a standard format proposed in studies of microzonation and its application in computer systems, which allows to optimize and condense microzonation studies in a city. The results obtained from the PSHA are presented through to seismic hazard maps (hazard footprints), exceedance rate curves and uniform hazard spectrum for different spectral ordinates, between 0.01 and 5.0 seconds, associated to selected return periods: 72, 225, 475 and 2475 years.

  9. The utility of the apolipoprotein A1 remnant ratio in predicting incidence coronary heart disease in a primary prevention cohort: The Jackson Heart Study.

    PubMed

    May, Heidi T; Nelson, John R; Lirette, Seth T; Kulkarni, Krishnaji R; Anderson, Jeffrey L; Griswold, Michael E; Horne, Benjamin D; Correa, Adolfo; Muhlestein, Joseph B

    2016-05-01

    Dyslipidemia plays a significant role in the progression of cardiovascular disease. The apolipoprotein (apo) A1 remnant ratio (apo A1/VLDL3-C + IDL-C) has recently been shown to be a strong predictor of death/myocardial infarction risk among women >50 years undergoing angiography. However, whether this ratio is associated with coronary heart disease risk among other populations is unknown. We evaluated the apo A1 remnant ratio and its components for coronary heart disease incidence. Observational. Participants (N = 4722) of the Jackson Heart Study were evaluated. Baseline clinical characteristics and lipoprotein subfractions (Vertical Auto Profile method) were collected. Cox hazard regression analysis, adjusted by standard cardiovascular risk factors, was utilized to determine associations of lipoproteins with coronary heart disease. Those with new-onset coronary heart disease were older, diabetic, smokers, had less education, used more lipid-lowering medication, and had a more atherogenic lipoprotein profile. After adjustment, the apo A1 remnant ratio (hazard ratio = 0.67 per 1-SD, p = 0.002) was strongly associated with coronary heart disease incidence. This association appears to be driven by the IDL-C denominator (hazard ratio = 1.23 per 1-SD, p = 0.007). Remnants (hazard ratio = 1.21 per 1-SD, p = 0.017), but not apo A1 (hazard ratio = 0.85 per 1-SD, p = 0.121) or VLDL3-C (hazard ratio = 1.13 per 1-SD, p = 0.120) were associated with coronary heart disease. Standard lipids were not associated with coronary heart disease incidence. We found the apo A1 remnant ratio to be strongly associated with coronary heart disease. This ratio appears to better stratify risk than standard lipids, apo A1, and remnants among a primary prevention cohort of African Americans. Its utility requires further study as a lipoprotein management target for risk reduction. © The European Society of Cardiology 2015.

  10. Automated Hazard Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Riddle, F. J.

    2003-06-26

    The Automated Hazard Analysis (AHA) application is a software tool used to conduct job hazard screening and analysis of tasks to be performed in Savannah River Site facilities. The AHA application provides a systematic approach to the assessment of safety and environmental hazards associated with specific tasks, and the identification of controls regulations, and other requirements needed to perform those tasks safely. AHA is to be integrated into existing Savannah River site work control and job hazard analysis processes. Utilization of AHA will improve the consistency and completeness of hazard screening and analysis, and increase the effectiveness of the workmore » planning process.« less

  11. Job Loss, Unemployment and the Incidence of Hazardous Drinking during the Late 2000s Recession in Europe among Adults Aged 50-64 Years.

    PubMed

    Bosque-Prous, Marina; Espelt, Albert; Sordo, Luis; Guitart, Anna M; Brugal, M Teresa; Bravo, Maria J

    2015-01-01

    To estimate the incidence of hazardous drinking in middle-aged people during an economic recession and ascertain whether individual job loss and contextual changes in unemployment influence the incidence rate in that period. Longitudinal study based on two waves of the SHARE project (Survey of Health, Ageing and Retirement in Europe). Individuals aged 50-64 years from 11 European countries, who were not hazardous drinkers at baseline (n = 7,615), were selected for this study. We estimated the cumulative incidence of hazardous drinking (≥40g and ≥20g of pure alcohol on average in men and women, respectively) between 2006 and 2012. Furthermore, in the statistical analysis, multilevel Poisson regression models with robust variance were fitted and obtained Risk Ratios (RR) and their 95% Confidence Intervals (95%CI). Over a 6-year period, 505 subjects became hazardous drinkers, with cumulative incidence of 6.6 per 100 persons between 2006 and 2012 (95%CI:6.1-7.2). Age [RR = 1.02 (95%CI:1.00-1.04)] and becoming unemployed [RR = 1.55 (95%CI:1.08-2.23)] were independently associated with higher risk of becoming a hazardous drinker. Conversely, having poorer self-perceived health was associated with lower risk of becoming a hazardous drinker [RR = 0.75 (95%CI:0.60-0.95)]. At country-level, an increase in the unemployment rate during the study period [RR = 1.32 (95%CI:1.17-1.50)] and greater increases in the household disposable income [RR = 0.97 (95%CI:0.95-0.99)] were associated with risk of becoming a hazardous drinker. Job loss among middle-aged individuals during the economic recession was positively associated with becoming a hazardous drinker. Changes in country-level variables were also related to this drinking pattern.

  12. Hazardous Waste

    MedlinePlus

    ... use them properly, many chemicals can still harm human health and the environment. When you throw these substances away, they become hazardous waste. Some hazardous wastes come from products in our ...

  13. Effect of Variable Compression Ratio on Performance of a Diesel Engine Fueled with Karanja Biodiesel and its Blends

    NASA Astrophysics Data System (ADS)

    Mishra, Rahul Kumar; soota, Tarun, Dr.; singh, Ranjeet

    2017-08-01

    Rapid exploration and lavish consumption of underground petroleum resources have led to the scarcity of underground fossil fuels moreover the toxic emissions from such fuels are pernicious which have increased the health hazards around the world. So the aim was to find an alternative fuel which would meet the requirements of petroleum or fossil fuels. Biodiesel is a clean, renewable and bio-degradable fuel having several advantages, one of the most important of which is being its eco-friendly and better knocking characteristics than diesel fuel. In this work the performance of Karanja oil was analyzed on a four stroke, single cylinder, water cooled, variable compression ratio diesel engine. The fuel used was 5% - 25% karanja oil methyl ester by volume in diesel. The results such obtained are compared with standard diesel fuel. Several properties i.e. Brake Thermal Efficiency, Brake Specific Fuel Consumptions, Exhaust Gas Temperature are determined at all operating conditions & at variable compression ratio 17 and 17.5.

  14. The West Virginia university forest hazard rating study: the hazards of hazard rating

    Treesearch

    Ray R., Jr. Hicks; David E. Fosbroke; Shrivenkar Kosuri; Charles B. Yuill

    1991-01-01

    The West Virginia University (WVU) Forest is a 7,600-acre tract located along the leading edge of gypsy moth infestation. The hazard rating study at the WVU Forest serves three objectives. First, hazard rating is being used to determine the extent and distribution of damage that can be expected when gypsy moth defoliation occurs. Second, susceptibility and...

  15. Probabilistic, Seismically-Induced Landslide Hazard Mapping of Western Oregon

    NASA Astrophysics Data System (ADS)

    Olsen, M. J.; Sharifi Mood, M.; Gillins, D. T.; Mahalingam, R.

    2015-12-01

    Earthquake-induced landslides can generate significant damage within urban communities by damaging structures, obstructing lifeline connection routes and utilities, generating various environmental impacts, and possibly resulting in loss of life. Reliable hazard and risk maps are important to assist agencies in efficiently allocating and managing limited resources to prepare for such events. This research presents a new methodology in order to communicate site-specific landslide hazard assessments in a large-scale, regional map. Implementation of the proposed methodology results in seismic-induced landslide hazard maps that depict the probabilities of exceeding landslide displacement thresholds (e.g. 0.1, 0.3, 1.0 and 10 meters). These maps integrate a variety of data sources including: recent landslide inventories, LIDAR and photogrammetric topographic data, geology map, mapped NEHRP site classifications based on available shear wave velocity data in each geologic unit, and USGS probabilistic seismic hazard curves. Soil strength estimates were obtained by evaluating slopes present along landslide scarps and deposits for major geologic units. Code was then developed to integrate these layers to perform a rigid, sliding block analysis to determine the amount and associated probabilities of displacement based on each bin of peak ground acceleration in the seismic hazard curve at each pixel. The methodology was applied to western Oregon, which contains weak, weathered, and often wet soils at steep slopes. Such conditions have a high landslide hazard even without seismic events. A series of landslide hazard maps highlighting the probabilities of exceeding the aforementioned thresholds were generated for the study area. These output maps were then utilized in a performance based design framework enabling them to be analyzed in conjunction with other hazards for fully probabilistic-based hazard evaluation and risk assessment. a) School of Civil and Construction

  16. International normalized ratio (INR) testing in Europe: between-laboratory comparability of test results obtained by Quick and Owren reagents.

    PubMed

    Meijer, Piet; Kynde, Karin; van den Besselaar, Antonius M H P; Van Blerk, Marjan; Woods, Timothy A L

    2018-04-12

    This study was designed to obtain an overview of the analytical quality of the prothrombin time, reported as international normalized ratio (INR) and to assess the variation of INR results between European laboratories, the difference between Quick-type and Owren-type methods and the effect of using local INR calibration or not. In addition, we assessed the variation in INR results obtained for a single donation in comparison with a pool of several plasmas. A set of four different lyophilized plasma samples were distributed via national EQA organizations to participating laboratories for INR measurement. Between-laboratory variation was lower in the Owren group than in the Quick group (on average: 6.7% vs. 8.1%, respectively). Differences in the mean INR value between the Owren and Quick group were relatively small (<0.20 INR). Between-laboratory variation was lower after local INR calibration (CV: 6.7% vs. 8.6%). For laboratories performing local calibration, the between-laboratory variation was quite similar for the Owren and Quick group (on average: 6.5% and 6.7%, respectively). Clinically significant differences in INR results (difference in INR>0.5) were observed between different reagents. No systematic significant differences in the between-laboratory variation for a single-plasma sample and a pooled plasma sample were observed. The comparability for laboratories using local calibration of their thromboplastin reagent is better than for laboratories not performing local calibration. Implementing local calibration is strongly recommended for the measurement of INR.

  17. Assessment of Uncertainties Related to Seismic Hazard Using Fuzzy Analysis

    NASA Astrophysics Data System (ADS)

    Jorjiashvili, N.; Yokoi, T.; Javakhishvili, Z.

    2013-05-01

    Seismic hazard analysis in last few decades has been become very important issue. Recently, new technologies and available data have been improved that helped many scientists to understand where and why earthquakes happen, physics of earthquakes, etc. They have begun to understand the role of uncertainty in Seismic hazard analysis. However, there is still significant problem how to handle existing uncertainty. The same lack of information causes difficulties to quantify uncertainty accurately. Usually attenuation curves are obtained in statistical way: regression analysis. Statistical and probabilistic analysis show overlapped results for the site coefficients. This overlapping takes place not only at the border between two neighboring classes, but also among more than three classes. Although the analysis starts from classifying sites using the geological terms, these site coefficients are not classified at all. In the present study, this problem is solved using Fuzzy set theory. Using membership functions the ambiguities at the border between neighboring classes can be avoided. Fuzzy set theory is performed for southern California by conventional way. In this study standard deviations that show variations between each site class obtained by Fuzzy set theory and classical way are compared. Results on this analysis show that when we have insufficient data for hazard assessment site classification based on Fuzzy set theory shows values of standard deviations less than obtained by classical way which is direct proof of less uncertainty.

  18. Flood hazard assessment in areas prone to flash flooding

    NASA Astrophysics Data System (ADS)

    Kvočka, Davor; Falconer, Roger A.; Bray, Michaela

    2016-04-01

    Contemporary climate projections suggest that there will be an increase in the occurrence of high-intensity rainfall events in the future. These precipitation extremes are usually the main cause for the emergence of extreme flooding, such as flash flooding. Flash floods are among the most unpredictable, violent and fatal natural hazards in the world. Furthermore, it is expected that flash flooding will occur even more frequently in the future due to more frequent development of extreme weather events, which will greatly increase the danger to people caused by flash flooding. This being the case, there will be a need for high resolution flood hazard maps in areas susceptible to flash flooding. This study investigates what type of flood hazard assessment methods should be used for assessing the flood hazard to people caused by flash flooding. Two different types of flood hazard assessment methods were tested: (i) a widely used method based on an empirical analysis, and (ii) a new, physically based and experimentally calibrated method. Two flash flood events were considered herein, namely: the 2004 Boscastle flash flood and the 2007 Železniki flash flood. The results obtained in this study suggest that in the areas susceptible to extreme flooding, the flood hazard assessment should be conducted using methods based on a mechanics-based analysis. In comparison to standard flood hazard assessment methods, these physically based methods: (i) take into account all of the physical forces, which act on a human body in floodwater, (ii) successfully adapt to abrupt changes in the flow regime, which often occur for flash flood events, and (iii) rapidly assess a flood hazard index in a relatively short period of time.

  19. Charon/Pluto Mass Ratio Obtained with HST CCD Observations in 1991 and 1993

    NASA Technical Reports Server (NTRS)

    Null, George W.

    1995-01-01

    We have analyzed Hubble Space Telescope wide field camera observations of Pluto, Charon, and a reference star, acquired in 1991 and 1993, to observe Pluto's barycentric motion and determine the Charon/Pluto mass ratio, q = 0.1237 +/-0.0081, with 6.5% accuracy. Solution values for Charon orbital elements include the semimajor axis, a = 19662 +/-81 km; inclination, i = 96.57 +/-0.24 deg; eccentricity, e = 0.0072 +/-0.0067; longitude of periapsis, w = 2 +/-35 deg; and mean longitude, l = 123.58 +/-0.43 deg. These elements are referred to the J2000 Earth equator and equinox at epoch JED 2446600.5.

  20. Updated Colombian Seismic Hazard Map

    NASA Astrophysics Data System (ADS)

    Eraso, J.; Arcila, M.; Romero, J.; Dimate, C.; Bermúdez, M. L.; Alvarado, C.

    2013-05-01

    possible to determinate environments and scenarios where the seismic hazard is a function of distance and magnitude and also the principal seismic sources that contribute to the seismic hazard at each site (dissagregation). This project was conducted by the Servicio Geológico Colombiano (Colombian Geological Survey) and the Universidad Nacional de Colombia (National University of Colombia), with the collaboration of national and foreign experts and the National System of Prevention and Attention of Disaster (SNPAD). It is important to stand out that this new seismic hazard map was used in the updated national building code (NSR-10). A new process is ongoing in order to improve and present the Seismic Hazard Map in terms of intensity. This require new knowledge in site effects, in both local and regional scales, checking the existing and develop new acceleration to intensity relationships, in order to obtain results more understandable and useful for a wider range of users, not only in the engineering field, but also all the risk assessment and management institutions, research and general community.

  1. Hazard evaluation of inorganics, singly and in mixtures, to Flannelmouth Sucker Catostomus latipinnis in the San Juan River, New Mexico

    USGS Publications Warehouse

    Hamilton, S.J.; Buhl, K.J.

    1997-01-01

    Larval flannelmouth sucker (Catostomus latipinnis) were exposed to arsenate, boron, copper, molybdenum, selenate, selenite, uranium, vanadium, and zinc singly, and to five mixtures of five to nine inorganics. The exposures were conducted in reconstituted water representative of the San Juan River near Shiprock, New Mexico. The mixtures simulated environmental ratios reported for sites along the San Juan River (San Juan River backwater, Fruitland marsh, Hogback East Drain, Mancos River, and McElmo Creek). The rank order of the individual inorganics, from most to least toxic, was: copper > zinc > vanadium > selenite > selenate > arsenate > uranium > boron > molybdenum. All five mixtures exhibited additive toxicity to flannelmouth sucker. In a limited number of tests, 44-day-old and 13-day-old larvae exhibited no difference in sensitivity to three mixtures. Copper was the major toxic component in four mixtures (San Juan backwater, Hogback East Drain, Mancos River, and McElmo Creek), whereas zinc was the major toxic component in the Fruitland marsh mixture, which did not contain copper. The Hogback East Drain was the most toxic mixture tested. Comparison of 96-h LC50values with reported environmental water concentrations from the San Juan River revealed low hazard ratios for arsenic, boron, molybdenum, selenate, selenite, uranium, and vanadium, moderate hazard ratios for zinc and the Fruitland marsh mixture, and high hazard ratios for copper at three sites and four environmental mixtures representing a San Juan backwater, Hogback East Drain, Mancos River, and McElmo Creek. The high hazard ratios suggest that inorganic contaminants could adversely affect larval flannelmouth sucker in the San Juan River at four sites receiving elevated inorganics.

  2. Flood hazard, vulnerability, and risk assessment for human life

    NASA Astrophysics Data System (ADS)

    Pan, T.; Chang, T.; Lai, J.; Hsieh, M.; Tan, Y.; Lin, Y.

    2011-12-01

    Flood risk assessment is an important issue for the countries suffering tropical cyclones and monsoon. Taiwan is located in the hot zone of typhoon tracks in the Western Pacific. There are three to five typhoons landing Taiwan every year. Typhoons and heavy rainfalls often cause inundation disaster rising with the increase of population and the development of social economy. The purpose of this study is to carry out the flood hazard, vulnerability and risk in term of human life. Based on the concept that flood risk is composed by flood hazard and vulnerability, a inundation simulation is performed to evaluate the factors of flood hazard for human life according to base flood (100-year return period). The flood depth, velocity and rising ratio are the three factors of flood hazards. Furthermore, the factors of flood vulnerability are identified in terms of human life that are classified into two main factors, residents and environment. The sub factors related to residents are the density of population and the density of vulnerable people including elders, youngers and disabled persons. The sub factors related to environment include the the number of building floors, the locations of buildings, the and distance to rescue center. The analytic hierarchy process (AHP) is adopted to determine the weights of these factors. The risk matrix is applied to show the risk from low to high based on the evaluation of flood hazards and vulnerabilities. The Tseng-Wen River watershed is selected as the case study because a serious flood was induced by Typhoon Morakot in 2009, which produced a record-breaking rainfall of 2.361mm in 48 hours in the last 50 years. The results of assessing the flood hazard, vulnerability and risk in term of human life could improve the emergency operation for flood disaster to prepare enough relief goods and materials during typhoon landing.

  3. Multi-hazards risk assessment at different levels

    NASA Astrophysics Data System (ADS)

    Frolova, N.; Larionov, V.; Bonnin, J.

    2012-04-01

    Natural and technological disasters are becoming more frequent and devastating. Social and economic losses due to those events increase annually, which is definitely in relation with evolution of society. Natural hazards identification and analysis, as well natural risk assessment taking into account secondary technological accidents are the first steps in prevention strategy aimed at saving lives and protecting property against future events. The paper addresses methodological issues of natural and technological integrated risk assessment and mapping at different levels [1, 2]. At the country level the most hazardous natural processes, which may results in fatalities, injuries and economic loss in the Russian Federation, are considered. They are earthquakes, landslides, mud flows, floods, storms, avalanches. The special GIS environment for the country territory was developed which includes information about hazards' level and reoccurrence, an impact databases for the last 20 years, as well as models for estimating damage and casualties caused by these hazards. Federal maps of seismic individual and collective risk, as well as multi-hazards natural risk maps are presented. The examples of regional seismic risk assessment taking into account secondary accidents at fire, explosion and chemical hazardous facilities and regional integrated risk assessment are given for the earthquake prone areas of the Russian Federation. The paper also gives examples of loss computations due to scenario earthquakes taking into account accidents trigged by strong events at critical facilities: fire and chemical hazardous facilities, including oil pipe lines routes located in the earthquake prone areas. The estimations of individual seismic risk obtained are used by EMERCOM of the Russian Federation, as well as by other federal and local authorities, for planning and implementing preventive measures, aimed at saving lives and protecting property against future disastrous events. The

  4. Hazardous Waste Roundup

    ERIC Educational Resources Information Center

    Farenga, Stephen J.; Joyce, Beverly A.; Ness, Daniel

    2004-01-01

    According to the Environmental Protection Agency (EPA), Americans generate approximately 1.6 million tons of hazardous household waste every year. When most people think of hazardous waste, they generally think of materials used in construction, the defense industry, mining, manufacturing, and agriculture. Few people think of hazardous substances…

  5. Risk assessment of debris flow hazards in natural slope

    NASA Astrophysics Data System (ADS)

    Choi, Junghae; Chae, Byung-gon; Liu, Kofei; Wu, Yinghsin

    2016-04-01

    The study area is located at north-east part of South Korea. Referring to the map of landslide sus-ceptibility (KIGAM, 2009) from Korea Institute of Geoscience and Mineral Resources (KIGAM for short), there are large areas of potential landslide in high probability on slope land of mountain near the study area. Besides, recently some severe landslide-induced debris flow hazards occurred in this area. So this site is convinced to be prone to debris flow haz-ards. In order to mitigate the influence of hazards, the assessment of potential debris flow hazards is very important and essential. In this assessment, we use Debris-2D, debris flow numerical program, to assess the potential debris flow hazards. The worst scenario is considered for simulation. The input mass sources are determined using landslide susceptibility map. The water input is referred to the daily accumulative rainfall in the past debris flow event in study area. The only one input material property, i.e. yield stress, is obtained using calibration test. The simulation results show that the study area has po-tential to be impacted by debris flow. Therefore, based on simulation results, to mitigate debris flow hazards, we can propose countermeasures, including building check dams, constructing a protection wall in study area, and installing instruments for active monitoring of debris flow hazards. Acknowledgements:This research was supported by the Public Welfare & Safety Research Program through the National Research Foundation of Korea(NRF) funded by the Ministry of Science, ICT & Future Planning (NRF-2012M3A2A1050983)

  6. Social vulnerability of rural households to flood hazards in western mountainous regions of Henan province, China

    NASA Astrophysics Data System (ADS)

    Liu, D. L.; Li, Y.

    2015-11-01

    Evaluating social vulnerability is a crucial issue in risk and disaster management. In this study, a household social vulnerability index (HSVI) to flood hazards was developed and used to assess the social vulnerability of rural households in western mountainous regions of Henan province, China. Eight key indicators were indentified through interactive discussions with multidisciplinary specialists and local farmers, and their weights were determined using principle component analysis (PCA). The results showed that (1) the ratio of perennial working in other places, hazard-related training and illiteracy ratio (15+) were the most dominant factors to social vulnerability. (2) The numbers of high, moderate and low vulnerable households were 14, 64 and 16, respectively, which accounted for 14.9, 68.1, and 17.0 % of the total interviewed rural households, respectively. (3) The correlation coefficient between household social vulnerability scores and casualties in a storm flood in July 2010 was significant at 0.05 significance level (r = 0.248), which indicated that the selected indicators and their weights were valid. (4) Some mitigation strategies to reduce the household social vulnerability to flood hazards were proposed based on the assessment results. The results provide useful information for rural households and local governments to prepare, mitigate and response to flood hazards.

  7. Assessment of the Casualty Risk of Multiple Meteorological Hazards in China

    PubMed Central

    Xu, Wei; Zhuo, Li; Zheng, Jing; Ge, Yi; Gu, Zhihui; Tian, Yugang

    2016-01-01

    A study of the frequency, intensity, and risk of extreme climatic events or natural hazards is important for assessing the impacts of climate change. Many models have been developed to assess the risk of multiple hazards, however, most of the existing approaches can only model the relative levels of risk. This paper reports the development of a method for the quantitative assessment of the risk of multiple hazards based on information diffusion. This method was used to assess the risks of loss of human lives from 11 types of meteorological hazards in China at the prefectural and provincial levels. Risk curves of multiple hazards were obtained for each province and the risks of 10-year, 20-year, 50-year, and 100-year return periods were mapped. The results show that the provinces (municipalities, autonomous regions) in southeastern China are at higher risk of multiple meteorological hazards as a result of their geographical location and topography. The results of this study can be used as references for the management of meteorological disasters in China. The model can be used to quantitatively calculate the risks of casualty, direct economic losses, building collapse, and agricultural losses for any hazards at different spatial scales. PMID:26901210

  8. Assessment of the Casualty Risk of Multiple Meteorological Hazards in China.

    PubMed

    Xu, Wei; Zhuo, Li; Zheng, Jing; Ge, Yi; Gu, Zhihui; Tian, Yugang

    2016-02-17

    A study of the frequency, intensity, and risk of extreme climatic events or natural hazards is important for assessing the impacts of climate change. Many models have been developed to assess the risk of multiple hazards, however, most of the existing approaches can only model the relative levels of risk. This paper reports the development of a method for the quantitative assessment of the risk of multiple hazards based on information diffusion. This method was used to assess the risks of loss of human lives from 11 types of meteorological hazards in China at the prefectural and provincial levels. Risk curves of multiple hazards were obtained for each province and the risks of 10-year, 20-year, 50-year, and 100-year return periods were mapped. The results show that the provinces (municipalities, autonomous regions) in southeastern China are at higher risk of multiple meteorological hazards as a result of their geographical location and topography. The results of this study can be used as references for the management of meteorological disasters in China. The model can be used to quantitatively calculate the risks of casualty, direct economic losses, building collapse, and agricultural losses for any hazards at different spatial scales.

  9. Occupational hazards and safety measures amongst the paint factory workers in lagos, Nigeria.

    PubMed

    Awodele, Olufunsho; Popoola, Temidayo D; Ogbudu, Bawo S; Akinyede, Akin; Coker, Herbert A B; Akintonwa, Alade

    2014-06-01

    The manufacture of paint involves a variety of processes that present with medical hazards. Safety initiatives are hence introduced to limit hazard exposures and promote workplace safety. This aim of this study is to assess the use of available control measures/initiatives in selected paint factories in Lagos West Senatorial District, Nigeria. A total of 400 randomly selected paint factory workers were involved in the study. A well-structured World Health Organization standard questionnaire was designed and distributed to the workers to elicit information on awareness to occupational hazards, use of personal protective devices, and commonly experienced adverse symptoms. Urine samples were obtained from 50 workers randomly selected from these 400 participants, and the concentrations of the heavy metals (lead, cadmium, arsenic, and chromium) were determined using atomic absorption spectroscopy. The results show that 72.5% of the respondents are aware of the hazards associated with their jobs; 30% have had formal training on hazards and safety measures; 40% do not use personal protective devices, and 90% of the respondents reported symptoms relating to hazard exposure. There was a statistically significant (p < 0.05) increase in the mean heavy metal concentrations in the urine samples obtained from paint factory workers as compared with nonfactory workers. The need to develop effective frameworks that will initiate the integration and ensure implementation of safety regulations in paint factories is evident. Where these exist, there is a need to promote adherence to these practice guidelines.

  10. Effect of mixing ratio of food waste and rice husk co-digestion and substrate to inoculum ratio on biogas production.

    PubMed

    Haider, Muhammad Rizwan; Zeshan; Yousaf, Sohail; Malik, Riffat Naseem; Visvanathan, Chettiyappan

    2015-08-01

    Aim of this study was to find out suitable mixing ratio of food waste and rice husk for their co-digestion in order to overcome VFA accumulation in digestion of food waste alone. Four mixing ratios of food waste and rice husk with C/N ratios of 20, 25, 30 and 35 were subjected to a lab scale anaerobic batch experiment under mesophilic conditions. Highest specific biogas yield of 584L/kgVS was obtained from feedstock with C/N ratio of 20. Biogas yield decreased with decrease in food waste proportion. Further, fresh cow dung was used as inoculum to investigate optimum S/I ratio with the selected feedstock. In experiment 2, feedstock with C/N ratio 20 was subjected to anaerobic digestion at five S/I ratios of 0.25, 0.5, 1.0, 1.5 and 2.0. Specific biogas yield of 557L/kgVS was obtained at S/I ratio of 0.25. However, VFA accumulation occurred at higher S/I ratios due to higher organic loadings. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Applied Prevalence Ratio estimation with different Regression models: An example from a cross-national study on substance use research.

    PubMed

    Espelt, Albert; Marí-Dell'Olmo, Marc; Penelo, Eva; Bosque-Prous, Marina

    2016-06-14

    To examine the differences between Prevalence Ratio (PR) and Odds Ratio (OR) in a cross-sectional study and to provide tools to calculate PR using two statistical packages widely used in substance use research (STATA and R). We used cross-sectional data from 41,263 participants of 16 European countries participating in the Survey on Health, Ageing and Retirement in Europe (SHARE). The dependent variable, hazardous drinking, was calculated using the Alcohol Use Disorders Identification Test - Consumption (AUDIT-C). The main independent variable was gender. Other variables used were: age, educational level and country of residence. PR of hazardous drinking in men with relation to women was estimated using Mantel-Haenszel method, log-binomial regression models and poisson regression models with robust variance. These estimations were compared to the OR calculated using logistic regression models. Prevalence of hazardous drinkers varied among countries. Generally, men have higher prevalence of hazardous drinking than women [PR=1.43 (1.38-1.47)]. Estimated PR was identical independently of the method and the statistical package used. However, OR overestimated PR, depending on the prevalence of hazardous drinking in the country. In cross-sectional studies, where comparisons between countries with differences in the prevalence of the disease or condition are made, it is advisable to use PR instead of OR.

  12. ThinkHazard!: an open-source, global tool for understanding hazard information

    NASA Astrophysics Data System (ADS)

    Fraser, Stuart; Jongman, Brenden; Simpson, Alanna; Nunez, Ariel; Deparday, Vivien; Saito, Keiko; Murnane, Richard; Balog, Simone

    2016-04-01

    Rapid and simple access to added-value natural hazard and disaster risk information is a key issue for various stakeholders of the development and disaster risk management (DRM) domains. Accessing available data often requires specialist knowledge of heterogeneous data, which are often highly technical and can be difficult for non-specialists in DRM to find and exploit. Thus, availability, accessibility and processing of these information sources are crucial issues, and an important reason why many development projects suffer significant impacts from natural hazards. The World Bank's Global Facility for Disaster Reduction and Recovery (GFDRR) is currently developing a new open-source tool to address this knowledge gap: ThinkHazard! The main aim of the ThinkHazard! project is to develop an analytical tool dedicated to facilitating improvements in knowledge and understanding of natural hazards among non-specialists in DRM. It also aims at providing users with relevant guidance and information on handling the threats posed by the natural hazards present in a chosen location. Furthermore, all aspects of this tool will be open and transparent, in order to give users enough information to understand its operational principles. In this presentation, we will explain the technical approach behind the tool, which translates state-of-the-art probabilistic natural hazard data into understandable hazard classifications and practical recommendations. We will also demonstrate the functionality of the tool, and discuss limitations from a scientific as well as an operational perspective.

  13. Expanding CyberShake Physics-Based Seismic Hazard Calculations to Central California

    NASA Astrophysics Data System (ADS)

    Silva, F.; Callaghan, S.; Maechling, P. J.; Goulet, C. A.; Milner, K. R.; Graves, R. W.; Olsen, K. B.; Jordan, T. H.

    2016-12-01

    As part of its program of earthquake system science, the Southern California Earthquake Center (SCEC) has developed a simulation platform, CyberShake, to perform physics-based probabilistic seismic hazard analysis (PSHA) using 3D deterministic wave propagation simulations. CyberShake performs PSHA by first simulating a tensor-valued wavefield of Strain Green Tensors. CyberShake then takes an earthquake rupture forecast and extends it by varying the hypocenter location and slip distribution, resulting in about 500,000 rupture variations. Seismic reciprocity is used to calculate synthetic seismograms for each rupture variation at each computation site. These seismograms are processed to obtain intensity measures, such as spectral acceleration, which are then combined with probabilities from the earthquake rupture forecast to produce a hazard curve. Hazard curves are calculated at seismic frequencies up to 1 Hz for hundreds of sites in a region and the results interpolated to obtain a hazard map. In developing and verifying CyberShake, we have focused our modeling in the greater Los Angeles region. We are now expanding the hazard calculations into Central California. Using workflow tools running jobs across two large-scale open-science supercomputers, NCSA Blue Waters and OLCF Titan, we calculated 1-Hz PSHA results for over 400 locations in Central California. For each location, we produced hazard curves using both a 3D central California velocity model created via tomographic inversion, and a regionally averaged 1D model. These new results provide low-frequency exceedance probabilities for the rapidly expanding metropolitan areas of Santa Barbara, Bakersfield, and San Luis Obispo, and lend new insights into the effects of directivity-basin coupling associated with basins juxtaposed to major faults such as the San Andreas. Particularly interesting are the basin effects associated with the deep sediments of the southern San Joaquin Valley. We will compare hazard

  14. Multi-Hazard Interactions in Guatemala

    NASA Astrophysics Data System (ADS)

    Gill, Joel; Malamud, Bruce D.

    2017-04-01

    In this paper, we combine physical and social science approaches to develop a multi-scale regional framework for natural hazard interactions in Guatemala. The identification and characterisation of natural hazard interactions is an important input for comprehensive multi-hazard approaches to disaster risk reduction at a regional level. We use five transdisciplinary evidence sources to organise and populate our framework: (i) internationally-accessible literature; (ii) civil protection bulletins; (iii) field observations; (iv) stakeholder interviews (hazard and civil protection professionals); and (v) stakeholder workshop results. These five evidence sources are synthesised to determine an appropriate natural hazard classification scheme for Guatemala (6 hazard groups, 19 hazard types, and 37 hazard sub-types). For a national spatial extent (Guatemala), we construct and populate a "21×21" hazard interaction matrix, identifying 49 possible interactions between 21 hazard types. For a sub-national spatial extent (Southern Highlands, Guatemala), we construct and populate a "33×33" hazard interaction matrix, identifying 112 possible interactions between 33 hazard sub-types. Evidence sources are also used to constrain anthropogenic processes that could trigger natural hazards in Guatemala, and characterise possible networks of natural hazard interactions (cascades). The outcomes of this approach are among the most comprehensive interaction frameworks for national and sub-national spatial scales in the published literature. These can be used to support disaster risk reduction and civil protection professionals in better understanding natural hazards and potential disasters at a regional scale.

  15. School-based exposure to hazardous air pollutants and grade point average: A multi-level study.

    PubMed

    Grineski, Sara E; Clark-Reyna, Stephanie E; Collins, Timothy W

    2016-05-01

    The problem of environmental health hazards around schools is serious but it has been neglected by researchers and analysts. This is concerning because children are highly susceptible to the effects of chemical hazards. Some ecological studies have demonstrated that higher school-level pollution is associated with lower aggregate school-level standardized test scores likely, related to increased respiratory illnesses and/or impaired cognitive development. However, an important question remains unexamined: How do school-level exposures impact individual children's academic performance? To address this, we obtained socio-demographic and grades data from the parents of 1888 fourth and fifth grade children in the El Paso (Texas, USA) Independent School District in 2012. El Paso is located on the US-side of the Mexican border and has a majority Mexican-origin population. School-based hazardous air pollution (HAP) exposure was calculated using census block-level US Environmental Protection Agency National Air Toxics Assessment risk estimates for respiratory and diesel particulate matter (PM). School-level demographics were obtained from the school district. Multi-level models adjusting for individual-level covariates (e.g., age, sex, race/ethnicity, English proficiency, and economic deprivation) and school-level covariates (e.g., percent of students economically disadvantaged and student-teacher ratio) showed that higher school-level HAPs were associated with lower individual-level grade point averages. An interquartile range increase in school-level HAP exposure was associated with an adjusted 0.11-0.40 point decrease in individual students' grade point averages (GPAs), depending on HAP type and emission source. Respiratory risk from HAPs had a larger effect on GPA than did diesel PM risk. Non-road mobile and total respiratory risk had the largest effects on children's GPA of all HAP variables studied and only mother's level of education had a larger effect than those

  16. 78 FR 69310 - Hazardous Materials Table, Special Provisions, Hazardous Materials Communications, Emergency...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-11-19

    ... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Part 172 Hazardous Materials Table, Special Provisions, Hazardous Materials Communications, Emergency Response Information, Training Requirements, and Security Plans CFR Correction In Title 49 of the Code of...

  17. Time prediction of failure a type of lamps by using general composite hazard rate model

    NASA Astrophysics Data System (ADS)

    Riaman; Lesmana, E.; Subartini, B.; Supian, S.

    2018-03-01

    This paper discusses the basic survival model estimates to obtain the average predictive value of lamp failure time. This estimate is for the parametric model, General Composite Hazard Level Model. The random time variable model used is the exponential distribution model, as the basis, which has a constant hazard function. In this case, we discuss an example of survival model estimation for a composite hazard function, using an exponential model as its basis. To estimate this model is done by estimating model parameters, through the construction of survival function and empirical cumulative function. The model obtained, will then be used to predict the average failure time of the model, for the type of lamp. By grouping the data into several intervals and the average value of failure at each interval, then calculate the average failure time of a model based on each interval, the p value obtained from the tes result is 0.3296.

  18. Health Hazard Appraisal Counseling—Continuing Evaluation

    PubMed Central

    LaDou, Joseph; Sherwood, John N.; Hughes, Lewis

    1979-01-01

    A program of annual health examinations was expanded to include counseling based on a computerized appraisal of individual patients' specific health risk factors. Data obtained from a specially designed questionnaire, laboratory tests and a physical examination yielded a health hazard appraisal showing a number of weighted risk factors and their relation to ten leading causes of death as determined for that patient. From all of this information, a “risk age” was developed which could then be compared with the patient's “true age.” The results were reviewed with each patient, and methods of correcting health hazards were stressed. The first annual retesting of a group of 107 examinees showed a net risk age reduction of 1.4 years (formerly reported in this journal). The longer term follow-up reported in this paper showed a net risk reduction of 2.38 years in a group of 26 examinees. The net risk age reduction in the two groups represented 32 and 40 percent, respectively, of the achievable risk age reduction when patients comply with suggestions made during risk reduction counseling. These findings indicate that health hazard appraisal counseling is an effective method of altering priorities of health practices. PMID:425518

  19. How natural hazards influence Internet searches

    NASA Astrophysics Data System (ADS)

    Geyer, Adelina; Martí, Joan; Villaseñor, Antonio

    2017-04-01

    Effective dissemination of correct and easy-to-understand scientific information is one of the most imperative tasks of natural hazard assessment and risk management, being the media and the population the two fundamental groups of receptors. It has been observed how during the occurrence of hazardous natural phenomena, media and population desperately seek for information in all possible channels. Traditionally, these have been the radio and television, but over the past decades, the Internet has also become a significant information resource. Nevertheless, how the Internet search behavior changes during the occurrence of natural phenomena of significant societal impact (i.e. involving important human and/or economic losses) has never been analyzed so far. Focusing mainly on volcanism, we use here for the first time Internet search data provided by Google Trends to examine the search patterns of volcanology-related terms and how these may change during unrest periods or volcanic crises. Results obtained allow us to evaluate, at a global and local scale, the interest of society towards volcanological phenomena and its potential background knowledge of Earth Sciences. We show here how Internet search data turns to be a promising tool for the global and local monitoring of awareness and education background of society on natural phenomena in general, and volcanic hazards in particular.

  20. Seismic Hazard Assessment at Esfaraen‒Bojnurd Railway, North‒East of Iran

    NASA Astrophysics Data System (ADS)

    Haerifard, S.; Jarahi, H.; Pourkermani, M.; Almasian, M.

    2018-01-01

    The objective of this study is to evaluate the seismic hazard at the Esfarayen-Bojnurd railway using the probabilistic seismic hazard assessment (PSHA) method. This method was carried out based on a recent data set to take into account the historic seismicity and updated instrumental seismicity. A homogenous earthquake catalogue was compiled and a proposed seismic sources model was presented. Attenuation equations that recently recommended by experts and developed based upon earthquake data obtained from tectonic environments similar to those in and around the studied area were weighted and used for assessment of seismic hazard in the frame of logic tree approach. Considering a grid of 1.2 × 1.2 km covering the study area, ground acceleration for every node was calculated. Hazard maps at bedrock conditions were produced for peak ground acceleration, in addition to return periods of 74, 475 and 2475 years.

  1. Health Hazard Appraisal in Patient Counseling

    PubMed Central

    LaDou, Joseph; Sherwood, John N.; Hughes, Lewis

    1975-01-01

    A program of annual health examinations was expanded to include counseling based on a computerized appraisal of individual patients' specific health hazard factors. Data obtained from a specially designed questionnaire, laboratory tests and a physical examination yielded a printout showing a number of weighted risk factors and their relation to ten leading causes of death as determined for that patient. From all of this information, a risk (“apparent”) age was developed for the patient. The results were reviewed with each patient, and methods of correcting health hazards were stressed. A total of 488 persons were appraised, and 107 were randomly reappraised in less than a year, with the finding that the net risk age was reduced by 1.4 years. Such a reduction in risk age is significant; it indicates that appraisal-based counseling is an effective method of altering priorities of health practices. PMID:1114813

  2. Wind shear modeling for aircraft hazard definition

    NASA Technical Reports Server (NTRS)

    Frost, W.; Camp, D. W.; Wang, S. T.

    1978-01-01

    Mathematical models of wind profiles were developed for use in fast time and manned flight simulation studies aimed at defining and eliminating these wind shear hazards. A set of wind profiles and associated wind shear characteristics for stable and neutral boundary layers, thunderstorms, and frontal winds potentially encounterable by aircraft in the terminal area are given. Engineering models of wind shear for direct hazard analysis are presented in mathematical formulae, graphs, tables, and computer lookup routines. The wind profile data utilized to establish the models are described as to location, how obtained, time of observation and number of data points up to 500 m. Recommendations, engineering interpretations and guidelines for use of the data are given and the range of applicability of the wind shear models is described.

  3. Fast Risk Assessment Software For Natural Hazard Phenomena Using Georeference Population And Infrastructure Data Bases

    NASA Astrophysics Data System (ADS)

    Marrero, J. M.; Pastor Paz, J. E.; Erazo, C.; Marrero, M.; Aguilar, J.; Yepes, H. A.; Estrella, C. M.; Mothes, P. A.

    2015-12-01

    Disaster Risk Reduction (DRR) requires an integrated multi-hazard assessment approach towards natural hazard mitigation. In the case of volcanic risk, long term hazard maps are generally developed on a basis of the most probable scenarios (likelihood of occurrence) or worst cases. However, in the short-term, expected scenarios may vary substantially depending on the monitoring data or new knowledge. In this context, the time required to obtain and process data is critical for optimum decision making. Availability of up-to-date volcanic scenarios is as crucial as it is to have this data accompanied by efficient estimations of their impact among populations and infrastructure. To address this impact estimation during volcanic crises, or other natural hazards, a web interface has been developed to execute an ANSI C application. This application allows one to compute - in a matter of seconds - the demographic and infrastructure impact that any natural hazard may cause employing an overlay-layer approach. The web interface is tailored to users involved in the volcanic crises management of Cotopaxi volcano (Ecuador). The population data base and the cartographic basis used are of public domain, published by the National Office of Statistics of Ecuador (INEC, by its Spanish acronym). To run the application and obtain results the user is expected to upload a raster file containing information related to the volcanic hazard or any other natural hazard, and determine categories to group population or infrastructure potentially affected. The results are displayed in a user-friendly report.

  4. Factors associated with home hazards: Findings from the Malaysian Elders Longitudinal Research study.

    PubMed

    Romli, Muhammad H; Tan, Maw P; Mackenzie, Lynette; Lovarini, Meryl; Kamaruzzaman, Shahrul B; Clemson, Lindy

    2018-03-01

    Previous studies have investigated home hazards as a risk factor for falls without considering factors associated with the presence of home hazards. The present study aimed to determine patterns of home hazards among urban community-dwelling older Malaysians, and to identify factors contributing to home hazards. Cross-sectional data from the initial wave of the Malaysian Elders Longitudinal Research study were used. Basic demographics were obtained from the Global Questionnaire. Basic and instrumental activities of daily living were measured using the Katz and Lawton-Brody scales, and home hazards were identified using the Home Falls and Accidents Screening Tool. Participants were also asked if they had fallen in the previous 12 months. Data were analyzed from 1489 participants. Hazards were frequently identified (>30%) in the toilet and bathroom areas (no grab rail, no non-slip mat, distant toilet), slippery floors, no bedside light access and inappropriate footwear. Lower educational attainment, traditional housing, Chinese ethnicity, greater number of home occupants, lower monthly expenditure, poor vision and younger age were the factors independently associated with home hazards. This study provides evidence that home hazards are a product of the interaction of the individual's function within their home environment. Hazards are also influenced by local sociocultural and environmental factors. The relationship between home hazards and falls appears complex and deserves further evaluation. Geriatr Gerontol Int 2018; 18: 387-395. © 2017 Japan Geriatrics Society.

  5. Induction Hazard Assessment: The Variability of Geoelectric Responses During Geomagnetic Storms Within Common Hazard Zones

    NASA Astrophysics Data System (ADS)

    Cuttler, S. W.; Love, J. J.; Swidinsky, A.

    2017-12-01

    Geomagnetic field data obtained through the INTERMAGNET program are convolved with four validated EarthScope USArray impedances to estimate the geoelectric variations throughout the duration of a geomagnetic storm. A four day long geomagnetic storm began on June 22, 2016, and was recorded at the Brandon (BRD), Manitoba and Fredericksburg (FRD), Virginia magnetic observatories over four days. Two impedance tensors corresponding to each magnetic observatory produce extremely different responses, despite being within close geographical proximity. Estimated time series of the geoelectric field throughout the duration of the geomagnetic storm were calculated, providing an understanding of how the geoelectric field differs across small geographic distances within the same geomagnetic hazard zones derived from prior geomagnetic hazard assessment. We show that the geoelectric response of two sites within 200km of one another can differ by up to two orders of magnitude (4245 mV/km at one location and 38 mV/km at another location 125km away). In addition, we compare these results with estimations of the geoelectric field generated from synthetic 1-dimensional resistivity models commonly used to represent large geographic regions when assessing geomagnetically induced current (GIC) hazards. This comparison shows that estimations of the geomagnetic field from these models differ greatly from estimations produced from Earthscope USArray sites (1205 mV/km in the 1D and 4245 mV/km in the 3D case in one example). This study demonstrates that the application of uniform 1-dimensional resistivity models of the subsurface to wide geographic regions is insufficient to predict the geoelectric hazard at a given location. Furthermore an evaluation of the 3-dimensional resistivity distribution at a given location is necessary to produce a reliable estimation of how the geoelectric field evolves over the course of a geomagnetic storm.

  6. Migration and Environmental Hazards

    PubMed Central

    Hunter, Lori M.

    2011-01-01

    Losses due to natural hazards (e.g., earthquakes, hurricanes) and technological hazards (e.g., nuclear waste facilities, chemical spills) are both on the rise. One response to hazard-related losses is migration, with this paper offering a review of research examining the association between migration and environmental hazards. Using examples from both developed and developing regional contexts, the overview demonstrates that the association between migration and environmental hazards varies by setting, hazard types, and household characteristics. In many cases, however, results demonstrate that environmental factors play a role in shaping migration decisions, particularly among those most vulnerable. Research also suggests that risk perception acts as a mediating factor. Classic migration theory is reviewed to offer a foundation for examination of these associations. PMID:21886366

  7. 40 CFR 270.66 - Permits for boilers and industrial furnaces burning hazardous waste.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... blended, and blending ratios. (3) A detailed engineering description of the boiler or industrial furnace... 40 Protection of Environment 27 2011-07-01 2011-07-01 false Permits for boilers and industrial... PROGRAM Special Forms of Permits § 270.66 Permits for boilers and industrial furnaces burning hazardous...

  8. 40 CFR 270.66 - Permits for boilers and industrial furnaces burning hazardous waste.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... blended, and blending ratios. (3) A detailed engineering description of the boiler or industrial furnace... 40 Protection of Environment 28 2013-07-01 2013-07-01 false Permits for boilers and industrial... PROGRAM Special Forms of Permits § 270.66 Permits for boilers and industrial furnaces burning hazardous...

  9. 40 CFR 270.66 - Permits for boilers and industrial furnaces burning hazardous waste.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... blended, and blending ratios. (3) A detailed engineering description of the boiler or industrial furnace... 40 Protection of Environment 28 2012-07-01 2012-07-01 false Permits for boilers and industrial... PROGRAM Special Forms of Permits § 270.66 Permits for boilers and industrial furnaces burning hazardous...

  10. 40 CFR 270.66 - Permits for boilers and industrial furnaces burning hazardous waste.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... blended, and blending ratios. (3) A detailed engineering description of the boiler or industrial furnace... 40 Protection of Environment 27 2014-07-01 2014-07-01 false Permits for boilers and industrial... PROGRAM Special Forms of Permits § 270.66 Permits for boilers and industrial furnaces burning hazardous...

  11. 40 CFR 270.66 - Permits for boilers and industrial furnaces burning hazardous waste.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... blended, and blending ratios. (3) A detailed engineering description of the boiler or industrial furnace... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Permits for boilers and industrial... PROGRAM Special Forms of Permits § 270.66 Permits for boilers and industrial furnaces burning hazardous...

  12. The impact of neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio among patients with intrahepatic cholangiocarcinoma.

    PubMed

    Buettner, Stefan; Spolverato, Gaya; Kimbrough, Charles W; Alexandrescu, Sorin; Marques, Hugo P; Lamelas, Jorge; Aldrighetti, Luca; Gamblin, T Clark; Maithel, Shishir K; Pulitano, Carlo; Weiss, Matthew; Bauer, Todd W; Shen, Feng; Poultsides, George A; Marsh, J Wallis; IJzermans, Jan N M; Koerkamp, Bas Groot; Pawlik, Timothy M

    2018-06-11

    (hazard ratio: 1.04, 95% CI: 1.01-1.07; P = .002). Patients could be stratified into low- versus high-risk groups based on standard tumor-specific factors such as lymph node status, tumor size, number, and vascular invasion (C index 0.62). When neutrophil-to-lymphocyte ratio was added to the prognostic model, the discriminatory ability of the model improved (C index 0.71). Elevated neutrophil-to-lymphocyte ratio was independently associated with worse overall survival and improved the prognostic estimation of long-term survival among patients with intrahepatic cholangiocarcinoma undergoing resection. Copyright © 2018 Elsevier Inc. All rights reserved.

  13. Seismic hazard estimation of northern Iran using smoothed seismicity

    NASA Astrophysics Data System (ADS)

    Khoshnevis, Naeem; Taborda, Ricardo; Azizzadeh-Roodpish, Shima; Cramer, Chris H.

    2017-07-01

    This article presents a seismic hazard assessment for northern Iran, where a smoothed seismicity approach has been used in combination with an updated seismic catalog and a ground motion prediction equation recently found to yield good fit with data. We evaluate the hazard over a geographical area including the seismic zones of Azerbaijan, the Alborz Mountain Range, and Kopeh-Dagh, as well as parts of other neighboring seismic zones that fall within our region of interest. In the chosen approach, seismic events are not assigned to specific faults but assumed to be potential seismogenic sources distributed within regular grid cells. After performing the corresponding magnitude conversions, we decluster both historical and instrumental seismicity catalogs to obtain earthquake rates based on the number of events within each cell, and smooth the results to account for the uncertainty in the spatial distribution of future earthquakes. Seismicity parameters are computed for each seismic zone separately, and for the entire region of interest as a single uniform seismotectonic region. In the analysis, we consider uncertainties in the ground motion prediction equation, the seismicity parameters, and combine the resulting models using a logic tree. The results are presented in terms of expected peak ground acceleration (PGA) maps and hazard curves at selected locations, considering exceedance probabilities of 2 and 10% in 50 years for rock site conditions. According to our results, the highest levels of hazard are observed west of the North Tabriz and east of the North Alborz faults, where expected PGA values are between about 0.5 and 1 g for 10 and 2% probability of exceedance in 50 years, respectively. We analyze our results in light of similar estimates available in the literature and offer our perspective on the differences observed. We find our results to be helpful in understanding seismic hazard for northern Iran, but recognize that additional efforts are necessary to

  14. EFFECT OF LIQUID TO SOLID RATIO ON LEACHING OF METALS FROM MINERAL PROCESSING WASTE

    EPA Science Inventory

    Various anthropogenic activities generate hazardous solid wastes that are affluent in heavy metals, which can cause significant damage to the environment an human health. A mineral processing waste was used to study the effect of liquid to solid ratio (L/S) on the leaching behav...

  15. Natural hazards science strategy

    USGS Publications Warehouse

    Holmes, Robert R.; Jones, Lucile M.; Eidenshink, Jeffery C.; Godt, Jonathan W.; Kirby, Stephen H.; Love, Jeffrey J.; Neal, Christina A.; Plant, Nathaniel G.; Plunkett, Michael L.; Weaver, Craig S.; Wein, Anne; Perry, Suzanne C.

    2012-01-01

    The mission of the U.S. Geological Survey (USGS) in natural hazards is to develop and apply hazard science to help protect the safety, security, and economic well-being of the Nation. The costs and consequences of natural hazards can be enormous, and each year more people and infrastructure are at risk. USGS scientific research—founded on detailed observations and improved understanding of the responsible physical processes—can help to understand and reduce natural hazard risks and to make and effectively communicate reliable statements about hazard characteristics, such as frequency, magnitude, extent, onset, consequences, and where possible, the time of future events.To accomplish its broad hazard mission, the USGS maintains an expert workforce of scientists and technicians in the earth sciences, hydrology, biology, geography, social and behavioral sciences, and other fields, and engages cooperatively with numerous agencies, research institutions, and organizations in the public and private sectors, across the Nation and around the world. The scientific expertise required to accomplish the USGS mission in natural hazards includes a wide range of disciplines that this report refers to, in aggregate, as hazard science.In October 2010, the Natural Hazards Science Strategy Planning Team (H–SSPT) was charged with developing a long-term (10-year) Science Strategy for the USGS mission in natural hazards. This report fulfills that charge, with a document hereinafter referred to as the Strategy, to provide scientific observations, analyses, and research that are critical for the Nation to become more resilient to natural hazards. Science provides the information that decisionmakers need to determine whether risk management activities are worthwhile. Moreover, as the agency with the perspective of geologic time, the USGS is uniquely positioned to extend the collective experience of society to prepare for events outside current memory. The USGS has critical statutory

  16. The effects of building design on hazard of first service in Norwegian dairy cows.

    PubMed

    Martin, A D; Kielland, C; Nelson, S T; Østerås, O

    2015-12-01

    Reproductive inefficiency is one of the major production and economic constraints on modern dairy farms. The environment affects onset of ovarian activity in a cow postcalving and influences estrus behavior, which in turn affects a stockperson's ability to inseminate her at the correct time. This study used survival analysis to investigate effects of building design and animal factors on the postpartum hazard of first service (HFS) in freestall-housed Norwegian Red cows. The study was performed on 232 Norwegian dairy farms between 2004 and 2007. Data were obtained through on farm measurements and by accessing the Norwegian Dairy Herd Recording System. The final data set contained data on 38,436 calvings and 27,127 services. Univariate Cox proportional hazard analyses showed that herd size and milk yield were positively associated with HFS. Total free accessible area and free accessible area available per cow year were positively associated with the HFS, as was the number of freestalls available per cow. Cows housed on slatted floors had a lower HFS than those housed on solid floors. Conversely, cows housed on rubber floors had a higher HFS than cows on concrete floors. Dead-ending alleyways reduced the hazard of AI after calving. A multivariable Cox proportional hazards model, accounting for herd management by including a frailty term for herd, showed relationships between hazard of postpartum service and explanatory variables. Animals in herds with more than 50 cows had a higher HFS [hazard ratio (HR)=3.0] compared with those in smaller herds. The HFS was also higher (HR=4.3) if more than 8.8 m(2) of space was available per cow year compared with herds in which animals had less space. The HFS after calving increased with parity (parity 2 HR=0.5, parity ≥3 HR=1.7), and was reduced if a lactation began with dystocia (HR=0.82) or was a breed other than Norwegian Red (HR=0.2). The frailty term, herd, was large and highly significant indicating a significant

  17. Tourism hazard potentials in Mount Merapi: how to deal with the risk

    NASA Astrophysics Data System (ADS)

    Muthiah, J.; Muntasib, E. K. S. H.; Meilani, R.

    2018-05-01

    Mount Merapi as one of the most popular natural tourism destination in Indonesia, indicated as disaster prone area. Hazard management is required to ensure visitors safety. Hazard identification and mapping are prerequisite in developing proper hazard management recommendation. This study aimed to map hazard potentials’ geographical positions obtained with geographical positioning system and to identify the hazard management being implemented. Data collection was carried out in Mei – June 2017 through observation and interview. Hiking trail and Lava tour area was selected as the study site, since the sites are the main areas for tourism activities in Mount Merapi. The type of hazards found in the area included lava, tephra, eruption cloud, ash, earthquake, land slide, extreme weather, slope and loose rock. Early warning system had been developed in this area, however the mechanism to regulate tourism activities still had to be improved. Local tourism entrepreneurs should be involved in the network of early warning system stakeholders to ensure tourist safety, and their capacity should be improved in order to be able to perform the measures needed for handling accident and disaster occurrences. Interpretive media explaining hazard potentials may be used to improve visitors’ awareness and ability to cope with the risk.

  18. UNSAFE SEXUAL BEHAVIOUR ASSOCIATED WITH HAZARDOUS ALCOHOL USE AMONG STREET-INVOLVED YOUTH

    PubMed Central

    Fairbairn, Nadia; Wood, Evan; Dong, Huiru; Kerr, Thomas; DeBeck, Kora

    2016-01-01

    While risky sexual behaviours related to illicit drug use among street youth have been explored, the impacts of alcohol use have received less attention. This longitudinal study examined hazardous alcohol use among a population of street-involved youth, with particular attention to sexual and drug-related risk behaviours. Data were derived from the At-Risk Youth Study, a prospective cohort of street-involved youth in Vancouver, Canada. The outcome of interest was hazardous alcohol use defined by the US National Institute on Alcohol Abuse and Alcoholism. We used generalized estimating equations (GEEs) analyses to identify factors associated with hazardous alcohol use. Between 2005 and 2014, 1149 drug-using youth were recruited and 629 (55%) reported hazardous alcohol use in the previous 6 months during study follow-up. In multivariable GEE analyses, unprotected sex (adjusted odds ratio [AOR] = 1.28, 95% confidence interval [95% CI] = 1.12–1.46) and homelessness (AOR = 1.35, 95% CI = 1.19–1.54) were independently associated with hazardous alcohol use (all p < .001). Older age (AOR = 0.95, 95% CI = 0.92–0.99), Caucasian ethnicity (AOR = 0.74, 95% CI = 0.61–0.90), daily heroin use (AOR = 0.53, 95% CI = 0.42– 0.67), daily crack cocaine smoking (AOR = 0.73, 95% CI = 0.59–0.91), and daily crystal methamphetamine use (AOR = 0.52, 95% CI = 0.42–0.64) were negatively associated with hazardous alcohol use (all p < .05). In sub-analysis, consistent dose–response patterns were observed between levels of alcohol use and unprotected sex, homelessness, and daily heroin injection. In sum, hazardous alcohol use was positively associated with unsafe sexual behaviour and negatively associated with high-intensity drug use. Interventions to address hazardous alcohol use should be central to HIV prevention efforts for street-involved youth. PMID:27539676

  19. 76 FR 4276 - Hazardous Materials: Improving the Safety of Railroad Transportation of Hazardous Materials

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-25

    ...-0004] Hazardous Materials: Improving the Safety of Railroad Transportation of Hazardous Materials... hazardous materials program. DATES: The public meeting will be held on Tuesday, February 22, 2011, starting...--Hazardous Materials, FRA Office of Safety Assurance and Compliance, at least 4 business days before the date...

  20. Characteristics of hazardous material spills from reporting systems in California.

    PubMed Central

    Shaw, G M; Windham, G C; Leonard, A; Neutra, R R

    1986-01-01

    Data on hazardous material releases that occurred between January 1, 1982 and September 30, 1983 in California were obtained from the California Highway Patrol (CHP) and the US Department of Transportation (DOT). The majority of incidents involved highway transport of hazardous materials, although some information was available on air, rail, and stationary facility releases. Vehicle accidents and failure of or damage to the container were the most frequent causes of releases. Proportionately more hazardous materials incidents occurred in early summer than at other times of the year, during weekdays, and daytime hours. The largest proportions of incidents involved the chemical categories of corrosives and fuels. Reported exposures and injuries to response personnel and other people at the scene were relatively few; no fatalities were reported. Few incidents were reported in both data sources, suggesting that the examination of only one data source would yield a gross underestimate of the total number of hazardous materials incidents in California. The lack of available denominator data limits the interpretation of the findings. Images FIGURE 1 FIGURE 2 FIGURE 3 PMID:3963282

  1. Poisson's ratio of fiber-reinforced composites

    NASA Astrophysics Data System (ADS)

    Christiansson, Henrik; Helsing, Johan

    1996-05-01

    Poisson's ratio flow diagrams, that is, the Poisson's ratio versus the fiber fraction, are obtained numerically for hexagonal arrays of elastic circular fibers in an elastic matrix. High numerical accuracy is achieved through the use of an interface integral equation method. Questions concerning fixed point theorems and the validity of existing asymptotic relations are investigated and partially resolved. Our findings for the transverse effective Poisson's ratio, together with earlier results for random systems by other authors, make it possible to formulate a general statement for Poisson's ratio flow diagrams: For composites with circular fibers and where the phase Poisson's ratios are equal to 1/3, the system with the lowest stiffness ratio has the highest Poisson's ratio. For other choices of the elastic moduli for the phases, no simple statement can be made.

  2. The Ratio of Arginine to Dimethylarginines is Reduced and Predicts Outcomes in Patients with Severe Sepsis

    PubMed Central

    Gough, Michael S.; Morgan, Mary Anne M.; Mack, Cynthia M.; Darling, Denise C.; Frasier, Lauren M.; Doolin, Kathleen P.; Apostolakos, Michael J.; Stewart, Judith C.; Graves, Brian T.; Arning, Erland; Bottiglieri, Teodoro; Mooney, Robert A.; Frampton, Mark W.; Pietropaoli, Anthony P.

    2011-01-01

    Objective Arginine deficiency may contribute to microvascular dysfunction, but previous studies suggest that arginine supplementation may be harmful in sepsis. Systemic arginine availability can be estimated by measuring the ratio of arginine to its endogenous inhibitors, asymmetric and symmetric dimethylarginine. We hypothesized that the arginine to dimethylarginine (Arg/DMA) ratio is reduced in patients with severe sepsis and associated with severity of illness and outcomes. Design Case-control and prospective cohort study Setting Medical and surgical intensive care units of an academic medical center Patients and Subjects 109 severe sepsis and 50 control subjects Measurements and Main Results Plasma and urine were obtained in control subjects and within 48 hours of diagnosis in severe sepsis patients. The Arg/DMA ratio was higher in control subjects vs. sepsis patients ((median = 95 [inter-quartile range = 85 – 114]) vs. 34 [24 – 48], p < 0.001), and in hospital survivors vs. non-survivors ((39 [26 – 52]) vs. 27 [19 – 32], p = 0.004). The Arg/DMA ratio was correlated with Acute Physiology and Chronic Health Evaluation II score (Spearman’s correlation coefficient [rho] = − 0.40, p < 0.001) and organ-failure free days (rho = 0.30, p = 0.001). A declining Arg/DMA ratio was independently associated with hospital mortality (odds ratio =1.63 per quartile, 95% confidence interval [CI] = 1.00 – 2.65, p = 0.048) and risk of death over 6 months (hazard ratio = 1.41 per quartile, 95% CI = 1.01 – 1.98, p = 0.043). The Arg/DMA ratio was correlated with the urinary nitrate to creatinine ratio (rho = 0.46, p < 0.001). Conclusions The Arg/DMA ratio is associated with severe sepsis, severity of illness, and clinical outcomes. The Arg/DMA ratio may be a useful biomarker, and interventions designed to augment systemic arginine availability in severe sepsis may still be worthy of investigation. PMID:21378552

  3. Flood Hazard and Risk Analysis in Urban Area

    NASA Astrophysics Data System (ADS)

    Huang, Chen-Jia; Hsu, Ming-hsi; Teng, Wei-Hsien; Lin, Tsung-Hsien

    2017-04-01

    Typhoons always induce heavy rainfall during summer and autumn seasons in Taiwan. Extreme weather in recent years often causes severe flooding which result in serious losses of life and property. With the rapid industrial and commercial development, people care about not only the quality of life, but also the safety of life and property. So the impact of life and property due to disaster is the most serious problem concerned by the residents. For the mitigation of the disaster impact, the flood hazard and risk analysis play an important role for the disaster prevention and mitigation. In this study, the vulnerability of Kaohsiung city was evaluated by statistics of social development factor. The hazard factors of Kaohsiung city was calculated by simulated flood depth of six different return periods and four typhoon events which result in serious flooding in Kaohsiung city. The flood risk can be obtained by means of the flood hazard and social vulnerability. The analysis results provide authority to strengthen disaster preparedness and to set up more resources in high risk areas.

  4. Total lightning characteristics of recent hazardous weather events in Japan

    NASA Astrophysics Data System (ADS)

    Hobara, Y.; Kono, S.; Ogawa, T.; Heckman, S.; Stock, M.; Liu, C.

    2017-12-01

    In recent years, the total lightning (IC + CG) activity have attracted a lot of attention to improve the quality of prediction of hazardous weather phenomena (hail, wind gusts, tornadoes, heavy precipitation). Sudden increases of the total lightning flash rate so-called lightning jump (LJ) preceding the hazardous weather, reported in several studies, are one of the promising precursors. Although, increases in the frequency and intensity of these extreme weather events were reported in Japan, relationship with these events with total lightning have not studied intensively yet. In this paper, we will demonstrate the recent results from Japanese total lightning detection network (JTLN) in relation with hazardous weather events occurred in Japan in the period of 2014-2016. Automatic thunderstorm cell tracking was carried out based on the very high spatial and temporal resolution X-band MP radar echo data (1 min and 250 m) to correlate with total lightning activity. Results obtained reveal promising because the flash rate of total lightning tends to increase about 10 40 minutes before the onset of the extreme weather events. We also present the differences in lightning characteristics of thunderstorm cells between hazardous weather events and non-hazardous weather events, which is a vital information to improve the prediction efficiency.

  5. Action on Hazardous Wastes.

    ERIC Educational Resources Information Center

    EPA Journal, 1979

    1979-01-01

    U.S. EPA is gearing up to investigate about 300 hazardous waste dump sites per year that could pose an imminent health hazard. Prosecutions are expected to result from the priority effort at investigating illegal hazardous waste disposal. (RE)

  6. Volcano Hazards Program

    USGS Publications Warehouse

    Venezky, Dina Y.; Myers, Bobbie; Driedger, Carolyn

    2008-01-01

    Diagram of common volcano hazards. The U.S. Geological Survey Volcano Hazards Program (VHP) monitors unrest and eruptions at U.S. volcanoes, assesses potential hazards, responds to volcanic crises, and conducts research on how volcanoes work. When conditions change at a monitored volcano, the VHP issues public advisories and warnings to alert emergency-management authorities and the public. See http://volcanoes.usgs.gov/ to learn more about volcanoes and find out what's happening now.

  7. Documentation for the 2008 Update of the United States National Seismic Hazard Maps

    USGS Publications Warehouse

    Petersen, Mark D.; Frankel, Arthur D.; Harmsen, Stephen C.; Mueller, Charles S.; Haller, Kathleen M.; Wheeler, Russell L.; Wesson, Robert L.; Zeng, Yuehua; Boyd, Oliver S.; Perkins, David M.; Luco, Nicolas; Field, Edward H.; Wills, Chris J.; Rukstales, Kenneth S.

    2008-01-01

    The 2008 U.S. Geological Survey (USGS) National Seismic Hazard Maps display earthquake ground motions for various probability levels across the United States and are applied in seismic provisions of building codes, insurance rate structures, risk assessments, and other public policy. This update of the maps incorporates new findings on earthquake ground shaking, faults, seismicity, and geodesy. The resulting maps are derived from seismic hazard curves calculated on a grid of sites across the United States that describe the frequency of exceeding a set of ground motions. The USGS National Seismic Hazard Mapping Project developed these maps by incorporating information on potential earthquakes and associated ground shaking obtained from interaction in science and engineering workshops involving hundreds of participants, review by several science organizations and State surveys, and advice from two expert panels. The National Seismic Hazard Maps represent our assessment of the 'best available science' in earthquake hazards estimation for the United States (maps of Alaska and Hawaii as well as further information on hazard across the United States are available on our Web site at http://earthquake.usgs.gov/research/hazmaps/).

  8. Toward uniform probabilistic seismic hazard assessments for Southeast Asia

    NASA Astrophysics Data System (ADS)

    Chan, C. H.; Wang, Y.; Shi, X.; Ornthammarath, T.; Warnitchai, P.; Kosuwan, S.; Thant, M.; Nguyen, P. H.; Nguyen, L. M.; Solidum, R., Jr.; Irsyam, M.; Hidayati, S.; Sieh, K.

    2017-12-01

    Although most Southeast Asian countries have seismic hazard maps, various methodologies and quality result in appreciable mismatches at national boundaries. We aim to conduct a uniform assessment across the region by through standardized earthquake and fault databases, ground-shaking scenarios, and regional hazard maps. Our earthquake database contains earthquake parameters obtained from global and national seismic networks, harmonized by removal of duplicate events and the use of moment magnitude. Our active-fault database includes fault parameters from previous studies and from the databases implemented for national seismic hazard maps. Another crucial input for seismic hazard assessment is proper evaluation of ground-shaking attenuation. Since few ground-motion prediction equations (GMPEs) have used local observations from this region, we evaluated attenuation by comparison of instrumental observations and felt intensities for recent earthquakes with predicted ground shaking from published GMPEs. We then utilize the best-fitting GMPEs and site conditions into our seismic hazard assessments. Based on the database and proper GMPEs, we have constructed regional probabilistic seismic hazard maps. The assessment shows highest seismic hazard levels near those faults with high slip rates, including the Sagaing Fault in central Myanmar, the Sumatran Fault in Sumatra, the Palu-Koro, Matano and Lawanopo Faults in Sulawesi, and the Philippine Fault across several islands of the Philippines. In addition, our assessment demonstrates the important fact that regions with low earthquake probability may well have a higher aggregate probability of future earthquakes, since they encompass much larger areas than the areas of high probability. The significant irony then is that in areas of low to moderate probability, where building codes are usually to provide less seismic resilience, seismic risk is likely to be greater. Infrastructural damage in East Malaysia during the 2015

  9. Hazard assessment of inorganics to three endangered fish in the Green River, Utah

    USGS Publications Warehouse

    Hamilton, S.J.

    1995-01-01

    Acute toxicity tests were conducted with three life stages of Colorado squawfish (Ptychocheilus lucius), razorback sucker (Xyrauchen texanus), and bonytail (Gila elegans) in a reconstituted water quality simulating the middle part of the Green River of Utah. Tests were conducted with boron, lithium, selenate, selenite, uranium, vanadium, and zinc. The overall rank order of toxicity to all species and life stages combined from most to least toxic was vanadium = zinc > selenite > lithium = uranium > selenate > boron. There was no difference between the three species in their sensitivity to the seven inorganics based on a rank-order evaluation at the species level. Colorado squawfish were 2-5 times more sensitive to selenate and selenite at the swimup life stage than older stages, whereas razorback suckers displayed equal sensitivity among life stages. Bonytail exhibited equal sensitivity to selenite, but were five times more sensitive to selenate at the swimup life stage than the older stages. Comparison of 96-hr LC50 values with a limited number of environmental water concentrations in Ashley Creek, Utah, which receives irrigation drainwater, revealed moderate hazard ratios for boron, selenate, selenite, and zinc, low hazard ratios for uranium and vanadium, but unknown ratios for lithium. These inorganic contaminants in drainwaters may adversely affect endangered fish in the Green River.

  10. A geostatistical extreme-value framework for fast simulation of natural hazard events

    PubMed Central

    Stephenson, David B.

    2016-01-01

    We develop a statistical framework for simulating natural hazard events that combines extreme value theory and geostatistics. Robust generalized additive model forms represent generalized Pareto marginal distribution parameters while a Student’s t-process captures spatial dependence and gives a continuous-space framework for natural hazard event simulations. Efficiency of the simulation method allows many years of data (typically over 10 000) to be obtained at relatively little computational cost. This makes the model viable for forming the hazard module of a catastrophe model. We illustrate the framework by simulating maximum wind gusts for European windstorms, which are found to have realistic marginal and spatial properties, and validate well against wind gust measurements. PMID:27279768

  11. Introduction: Hazard mapping

    USGS Publications Warehouse

    Baum, Rex L.; Miyagi, Toyohiko; Lee, Saro; Trofymchuk, Oleksandr M

    2014-01-01

    Twenty papers were accepted into the session on landslide hazard mapping for oral presentation. The papers presented susceptibility and hazard analysis based on approaches ranging from field-based assessments to statistically based models to assessments that combined hydromechanical and probabilistic components. Many of the studies have taken advantage of increasing availability of remotely sensed data and nearly all relied on Geographic Information Systems to organize and analyze spatial data. The studies used a range of methods for assessing performance and validating hazard and susceptibility models. A few of the studies presented in this session also included some element of landslide risk assessment. This collection of papers clearly demonstrates that a wide range of approaches can lead to useful assessments of landslide susceptibility and hazard.

  12. Doubly Robust Additive Hazards Models to Estimate Effects of a Continuous Exposure on Survival.

    PubMed

    Wang, Yan; Lee, Mihye; Liu, Pengfei; Shi, Liuhua; Yu, Zhi; Abu Awad, Yara; Zanobetti, Antonella; Schwartz, Joel D

    2017-11-01

    The effect of an exposure on survival can be biased when the regression model is misspecified. Hazard difference is easier to use in risk assessment than hazard ratio and has a clearer interpretation in the assessment of effect modifications. We proposed two doubly robust additive hazards models to estimate the causal hazard difference of a continuous exposure on survival. The first model is an inverse probability-weighted additive hazards regression. The second model is an extension of the doubly robust estimator for binary exposures by categorizing the continuous exposure. We compared these with the marginal structural model and outcome regression with correct and incorrect model specifications using simulations. We applied doubly robust additive hazard models to the estimation of hazard difference of long-term exposure to PM2.5 (particulate matter with an aerodynamic diameter less than or equal to 2.5 microns) on survival using a large cohort of 13 million older adults residing in seven states of the Southeastern United States. We showed that the proposed approaches are doubly robust. We found that each 1 μg m increase in annual PM2.5 exposure was associated with a causal hazard difference in mortality of 8.0 × 10 (95% confidence interval 7.4 × 10, 8.7 × 10), which was modified by age, medical history, socioeconomic status, and urbanicity. The overall hazard difference translates to approximately 5.5 (5.1, 6.0) thousand deaths per year in the study population. The proposed approaches improve the robustness of the additive hazards model and produce a novel additive causal estimate of PM2.5 on survival and several additive effect modifications, including social inequality.

  13. A Comprehensive Probabilistic Tsunami Hazard Assessment: Multiple Sources and Short-Term Interactions

    NASA Astrophysics Data System (ADS)

    Anita, G.; Selva, J.; Laura, S.

    2011-12-01

    We develop a comprehensive and total probabilistic tsunami hazard assessment (TotPTHA), in which many different possible source types concur to the definition of the total tsunami hazard at given target sites. In a multi-hazard and multi-risk perspective, such an innovative approach allows, in principle, to consider all possible tsunamigenic sources, from seismic events, to slides, asteroids, volcanic eruptions, etc. In this respect, we also formally introduce and discuss the treatment of interaction/cascade effects in the TotPTHA analysis. We demonstrate how external triggering events may induce significant temporary variations in the tsunami hazard. Because of this, such effects should always be considered, at least in short-term applications, to obtain unbiased analyses. Finally, we prove the feasibility of the TotPTHA and of the treatment of interaction/cascade effects by applying this methodology to an ideal region with realistic characteristics (Neverland).

  14. Hazardous Waste Generators

    EPA Pesticide Factsheets

    Many industries generate hazardous waste. EPA regulates hazardous waste under the Resource Conservation and Recovery Act to ensure these wastes are managed in ways that are protective of human health and the environment.

  15. 76 FR 4823 - Hazardous Waste Management System; Identifying and Listing Hazardous Waste Exclusion

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-01-27

    ... Waste Management System; Identifying and Listing Hazardous Waste Exclusion AGENCY: Environmental... hazardous wastes. The Agency has decided to grant the petition based on an evaluation of waste-specific... excludes the petitioned waste from the requirements of hazardous waste regulations under the Resource...

  16. Hazardous Waste Permitting

    EPA Pesticide Factsheets

    To provide RCRA hazardous waste permitting regulatory information and resources permitted facilities, hazardous waste generators, and permit writers. To provide the public with information on how they can be involved in the permitting process.

  17. 76 FR 55846 - Hazardous Waste Management System: Identification and Listing of Hazardous Waste: Carbon Dioxide...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-09

    ... 2050-AG60 Hazardous Waste Management System: Identification and Listing of Hazardous Waste: Carbon... hazardous waste management under the Resource Conservation and Recovery Act (RCRA) to conditionally exclude... and recordkeeping requirements. 40 CFR Part 261 Environmental protection, Hazardous waste, Solid waste...

  18. Demonstration of improvement in the signal-to-noise ratio of Thomson scattering signal obtained by using a multi-pass optical cavity on the Tokyo Spherical Tokamak-2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Togashi, H., E-mail: togashi@fusion.k.u-tokyo.ac.jp; Ejiri, A.; Nakamura, K.

    2014-11-15

    The multi-pass Thomson scattering (TS) scheme enables obtaining many photons by accumulating multiple TS signals. The signal-to-noise ratio (SNR) depends on the accumulation number. In this study, we performed multi-pass TS measurements for ohmically heated plasmas, and the relationship between SNR and the accumulation number was investigated. As a result, improvement of SNR in this experiment indicated similar tendency to that calculated for the background noise dominant situation.

  19. Connecting Hazard Analysts and Risk Managers to Sensor Information.

    PubMed

    Le Cozannet, Gonéri; Hosford, Steven; Douglas, John; Serrano, Jean-Jacques; Coraboeuf, Damien; Comte, Jérémie

    2008-06-11

    Hazard analysts and risk managers of natural perils, such as earthquakes, landslides and floods, need to access information from sensor networks surveying their regions of interest. However, currently information about these networks is difficult to obtain and is available in varying formats, thereby restricting accesses and consequently possibly leading to decision-making based on limited information. As a response to this issue, state-of-the-art interoperable catalogues are being currently developed within the framework of the Group on Earth Observations (GEO) workplan. This article provides an overview of the prototype catalogue that was developed to improve access to information about the sensor networks surveying geological hazards (geohazards), such as earthquakes, landslides and volcanoes.

  20. Connecting Hazard Analysts and Risk Managers to Sensor Information

    PubMed Central

    Le Cozannet, Gonéri; Hosford, Steven; Douglas, John; Serrano, Jean-Jacques; Coraboeuf, Damien; Comte, Jérémie

    2008-01-01

    Hazard analysts and risk managers of natural perils, such as earthquakes, landslides and floods, need to access information from sensor networks surveying their regions of interest. However, currently information about these networks is difficult to obtain and is available in varying formats, thereby restricting accesses and consequently possibly leading to decision-making based on limited information. As a response to this issue, state-of-the-art interoperable catalogues are being currently developed within the framework of the Group on Earth Observations (GEO) workplan. This article provides an overview of the prototype catalogue that was developed to improve access to information about the sensor networks surveying geological hazards (geohazards), such as earthquakes, landslides and volcanoes. PMID:27879915

  1. Informing Workers of Chemical Hazards: The OSHA Hazard Communication Standard.

    ERIC Educational Resources Information Center

    American Chemical Society, Washington, DC.

    Practical information on how to implement a chemical-related safety program is outlined in this publication. Highlights of the federal Occupational Safety and Health Administrations (OSHA) Hazard Communication Standard are presented and explained. These include: (1) hazard communication requirements (consisting of warning labels, material safety…

  2. Seismic hazard maps for Haiti

    USGS Publications Warehouse

    Frankel, Arthur; Harmsen, Stephen; Mueller, Charles; Calais, Eric; Haase, Jennifer

    2011-01-01

    We have produced probabilistic seismic hazard maps of Haiti for peak ground acceleration and response spectral accelerations that include the hazard from the major crustal faults, subduction zones, and background earthquakes. The hazard from the Enriquillo-Plantain Garden, Septentrional, and Matheux-Neiba fault zones was estimated using fault slip rates determined from GPS measurements. The hazard from the subduction zones along the northern and southeastern coasts of Hispaniola was calculated from slip rates derived from GPS data and the overall plate motion. Hazard maps were made for a firm-rock site condition and for a grid of shallow shear-wave velocities estimated from topographic slope. The maps show substantial hazard throughout Haiti, with the highest hazard in Haiti along the Enriquillo-Plantain Garden and Septentrional fault zones. The Matheux-Neiba Fault exhibits high hazard in the maps for 2% probability of exceedance in 50 years, although its slip rate is poorly constrained.

  3. Documentation for Initial Seismic Hazard Maps for Haiti

    USGS Publications Warehouse

    Frankel, Arthur; Harmsen, Stephen; Mueller, Charles; Calais, Eric; Haase, Jennifer

    2010-01-01

    In response to the urgent need for earthquake-hazard information after the tragic disaster caused by the moment magnitude (M) 7.0 January 12, 2010, earthquake, we have constructed initial probabilistic seismic hazard maps for Haiti. These maps are based on the current information we have on fault slip rates and historical and instrumental seismicity. These initial maps will be revised and improved as more data become available. In the short term, more extensive logic trees will be developed to better capture the uncertainty in key parameters. In the longer term, we will incorporate new information on fault parameters and previous large earthquakes obtained from geologic fieldwork. These seismic hazard maps are important for the management of the current crisis and the development of building codes and standards for the rebuilding effort. The boundary between the Caribbean and North American Plates in the Hispaniola region is a complex zone of deformation. The highly oblique ~20 mm/yr convergence between the two plates (DeMets and others, 2000) is partitioned between subduction zones off of the northern and southeastern coasts of Hispaniola and strike-slip faults that transect the northern and southern portions of the island. There are also thrust faults within the island that reflect the compressional component of motion caused by the geometry of the plate boundary. We follow the general methodology developed for the 1996 U.S. national seismic hazard maps and also as implemented in the 2002 and 2008 updates. This procedure consists of adding the seismic hazard calculated from crustal faults, subduction zones, and spatially smoothed seismicity for shallow earthquakes and Wadati-Benioff-zone earthquakes. Each one of these source classes will be described below. The lack of information on faults in Haiti requires many assumptions to be made. These assumptions will need to be revisited and reevaluated as more fieldwork and research are accomplished. We made two sets of

  4. Prevalence and Correlates of Hazardous Drinking among Female Sex Workers in 13 Mexican Cities.

    PubMed

    Semple, Shirley J; Pitpitan, Eileen V; Chavarin, Claudia V; Strathdee, Steffanie A; Zavala, Rosa Icela; Aarons, Gregory A; Patterson, Thomas L

    2016-07-01

    To describe the prevalence and correlates of hazardous drinking among female sex workers (FSWs) at 13 sites throughout Mexico. FSWs (N = 1089) who were enrolled in a brief sexual risk reduction intervention (Mujer Segura) were queried about their sexual risk and substance use practices and their work contexts. Participants were classified as hazardous or non-hazardous drinkers based on the Alcohol Use Disorders test (AUDIT-C). Logistic regression models were used to examine individual, contextual, and community-level factors as correlates of hazardous drinking. Ninety-two percent of participants reported alcohol consumption in the past month. Among drinkers (N = 1001), 83% met AUDIT-C criteria for hazardous drinking. Factors that were independently associated with hazardous drinking included: drug use in the past month (adjusted odds ratio (AOR) = 3.31; 95% CI 1.29-8.45), being a cigarette smoker (AOR = 1.71; 95% CI 1.13-2.58), being a barmaid or dance hostess (AOR = 3.40; 95% CI 1.95-5.91), alcohol use before or during sex with clients (AOR = 7.78; 95% CI 4.84-12.52), and working in a city with a higher marginalization index (AOR = 1.07; 95% CI 1.04-1.11). Findings support the high prioritization by public health authorities of alcohol prevention and treatment programs for FSWs. © The Author 2015. Medical Council on Alcohol and Oxford University Press. All rights reserved.

  5. Prevalence and Correlates of Hazardous Drinking among Female Sex Workers in 13 Mexican Cities

    PubMed Central

    Semple, Shirley J.; Pitpitan, Eileen V.; Chavarin, Claudia V.; Strathdee, Steffanie A.; Zavala, Rosa Icela; Aarons, Gregory A.; Patterson, Thomas L.

    2016-01-01

    Aims To describe the prevalence and correlates of hazardous drinking among female sex workers (FSWs) at 13 sites throughout Mexico. Methods FSWs (N = 1089) who were enrolled in a brief sexual risk reduction intervention (Mujer Segura) were queried about their sexual risk and substance use practices and their work contexts. Participants were classified as hazardous or non-hazardous drinkers based on the Alcohol Use Disorders test (AUDIT-C). Logistic regression models were used to examine individual, contextual, and community-level factors as correlates of hazardous drinking. Results Ninety-two percent of participants reported alcohol consumption in the past month. Among drinkers (N = 1001), 83% met AUDIT-C criteria for hazardous drinking. Factors that were independently associated with hazardous drinking included: drug use in the past month (adjusted odds ratio (AOR) = 3.31; 95% CI 1.29—8.45), being a cigarette smoker (AOR = 1.71; 95% CI 1.13—2.58), being a barmaid or dance hostess (AOR = 3.40; 95% CI 1.95–5.91), alcohol use before or during sex with clients (AOR = 7.78; 95% CI 4.84–12.52), and working in a city with a higher marginalization index (AOR = 1.07; 95% CI 1.04–1.11). Conclusions Findings support the high prioritization by public health authorities of alcohol prevention and treatment programs for FSWs. PMID:26546017

  6. INTERNAL HAZARDS ANALYSIS FOR LICENSE APPLICATION

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    R.J. Garrett

    2005-02-17

    The purpose of this internal hazards analysis is to identify and document the internal hazards and potential initiating events associated with preclosure operations of the repository at Yucca Mountain. Internal hazards are those hazards presented by the operation of the facility and by its associated processes that can potentially lead to a radioactive release or cause a radiological hazard. In contrast to external hazards, internal hazards do not involve natural phenomena and external man-made hazards. This internal hazards analysis was performed in support of the preclosure safety analysis and the License Application for the Yucca Mountain Project. The methodology formore » this analysis provides a systematic means to identify internal hazards and potential initiating events that may result in a radiological hazard or radiological release during the repository preclosure period. These hazards are documented in tables of potential internal hazards and potential initiating events (Section 6.6) for input to the repository event sequence categorization process. The results of this analysis will undergo further screening and analysis based on the criteria that apply to the performance of event sequence analyses for the repository preclosure period. The evolving design of the repository will be re-evaluated periodically to ensure that internal hazards that have not been previously evaluated are identified.« less

  7. Alaska Seismic Hazards Safety Commission

    Science.gov Websites

    State Employees ASHSC State of Alaska search Alaska Seismic Hazards Safety Commission View of Anchorage and Commissions Alaska Seismic Hazards Safety Commission (ASHSC) main contant Alaska Seismic Hazards Safety Commission logo Alaska Seismic Hazards Safety Commission (ASHSC) - Mission The Alaska Seismic

  8. Risk assessment of major hazards and its application in urban planning: a case study.

    PubMed

    Zhou, Yafei; Liu, Mao

    2012-03-01

    With the rapid development of industry in China, the number of establishments that are proposed or under construction is increasing year by year, and many are industries that handle flammable, explosive, toxic, harmful, and dangerous substances. Accidents such as fire, explosion, and toxic diffusion inevitably happen. Accidents resulting from these major hazards in cities cause a large number of casualties and property losses. It is increasingly important to analyze the risk of major hazards in cities realistically and to suitably plan and utilize the surrounding land based on the risk analysis results, thereby reducing the hazards. A theoretical system for risk assessment of major hazards in cities is proposed in this article, and the major hazard risk for the entire city is analyzed quantitatively. Risks of various major accidents are considered together, superposition effect is analyzed, individual risk contours of the entire city are drawn out, and the level of risk in the city is assessed using "as low as reasonably practicable" guidelines. After the entire city's individual risk distribution is obtained, risk zones are divided according to corresponding individual risk value of HSE, and land-use planning suggestions are proposed. Finally, a city in China is used as an example to illustrate the risk assessment process of the city's major hazard and its application in urban land-use planning. The proposed method has a certain theoretical and practical significance in establishing and improving risk analysis of major hazard and urban land-use planning. On the one hand, major urban public risk is avoided; further, the land is utilized in the best possible way in order to obtain the maximum benefit from its use. © 2011 Society for Risk Analysis.

  9. Health behaviours as a predictor of quitting hazardous alcohol use in the Stockholm Public Health Cohort.

    PubMed

    Säfsten, Eleonor; Forsell, Yvonne; Ramstedt, Mats; Galanti, Maria R

    2018-06-01

    Adopting healthy behaviours may facilitate the transition from hazardous to non-hazardous use of alcohol, yet, longitudinal studies of health behaviours in relation to the cessation of hazardous alcohol use are rare. We addressed this question using data from a large population-based cohort of adults in Sweden (Stockholm Public Health Cohort). Participants from two sub-cohorts (inception in 2002 and 2010), with follow-up until the year 2014 were included. Health behaviours (tobacco use, diet and physical activity) and alcohol use were self-reported in questionnaire-based surveys. Hazardous alcohol use was defined as either usual weekly consumption (2002 sub-cohort) or heavy occasional alcohol consumption (2010 sub-cohort). Baseline hazardous drinkers with complete data constituted the analytical sample (n = 8946). Logistic regression was used to calculate the Odds Ratios and their 95% confidence intervals of quitting hazardous alcohol use, with tobacco use, diet and physical activity as predictors of change. In the 2002 sub-cohort, 28% reported non-hazardous use sustained through two consecutive follow-up points. In the 2010 sub-cohort, 36% of the participants reported non-hazardous use of alcohol at follow-up. Favourable health behaviours at baseline (e.g. no tobacco use, sufficient fruit intake and physical activity) were associated with a 19% to 75% higher of odds quitting hazardous alcohol use. Further, favourable changes in diet and tobacco cessation were associated with non-hazardous alcohol use at follow-up. As many as one-third of hazardous alcohol users may quit this drinking pattern in a medium-long term. Holding or achieving a healthy lifestyle may facilitate this transition.

  10. Probabilistic Volcanic Hazard and Risk Assessment

    NASA Astrophysics Data System (ADS)

    Marzocchi, W.; Neri, A.; Newhall, C. G.; Papale, P.

    2007-08-01

    Quantifying Long- and Short-Term Volcanic Hazard: Building Up a Common Strategy for Italian Volcanoes, Erice Italy, 8 November 2006 The term ``hazard'' can lead to some misunderstanding. In English, hazard has the generic meaning ``potential source of danger,'' but for more than 30 years [e.g., Fournier d'Albe, 1979], hazard has been also used in a more quantitative way, that reads, ``the probability of a certain hazardous event in a specific time-space window.'' However, many volcanologists still use ``hazard'' and ``volcanic hazard'' in purely descriptive and subjective ways. A recent meeting held in November 2006 at Erice, Italy, entitled ``Quantifying Long- and Short-Term Volcanic Hazard: Building up a Common Strategy for Italian Volcanoes'' (http://www.bo.ingv.it/erice2006) concluded that a more suitable term for the estimation of quantitative hazard is ``probabilistic volcanic hazard assessment'' (PVHA).

  11. Hazard pay: An effective antagonist

    NASA Technical Reports Server (NTRS)

    Alexander, R. E.

    1971-01-01

    Procedures for allocating hazardous pay to employees are outlined. According to the guidelines, only top level management can authorize hazardous tasks and decide if said task is indeed hazardous. The guidelines also state that hazardous jobs may be performed only if it is essential to finish a project and cannot be adequately safequarded.

  12. Hazard maps of Colima volcano, Mexico

    NASA Astrophysics Data System (ADS)

    Suarez-Plascencia, C.; Nunez-Cornu, F. J.; Escudero Ayala, C. R.

    2011-12-01

    (rockfall) and pyroclastic flows, b) Hazard map of lahars and debris flow, and c) Hazard map of ash-fall. The cartographic and database information obtained will be the basis for updating the Operational Plan of the Colima Volcano by the State Civil & Fire Protection Unit of Jalisco, Mexico, and the urban development plans of surrounding municipalities, in order to reduce their vulnerability to the hazards of the volcanic activity.

  13. Hazards in volcanic arcs

    NASA Astrophysics Data System (ADS)

    Sparks, S. R.

    2008-12-01

    Volcanic eruptions in arcs are complex natural phenomena, involving the movement of magma to the Earth's surface and interactions with the surrounding crust during ascent and with the surface environment during eruption, resulting in secondary hazards. Magma changes its properties profoundly during ascent and eruption and many of the underlying processes of heat and mass transfer and physical property changes that govern volcanic flows and magmatic interactions with the environment are highly non-linear. Major direct hazards include tephra fall, pyroclastic flows from explosions and dome collapse, volcanic blasts, lahars, debris avalanches and tsunamis. There are also health hazards related to emissions of gases and very fine volcanic ash. These hazards and progress in their assessment are illustrated mainly from the ongoing eruption of the Soufriere Hills volcano. Montserrat. There are both epistemic and aleatory uncertainties in the assessment of volcanic hazards, which can be large, making precise prediction a formidable objective. Indeed in certain respects volcanic systems and hazardous phenomena may be intrinsically unpredictable. As with other natural phenomena, predictions and hazards inevitably have to be expressed in probabilistic terms that take account of these uncertainties. Despite these limitations significant progress is being made in the ability to anticipate volcanic activity in volcanic arcs and, in favourable circumstances, make robust hazards assessments and predictions. Improvements in monitoring ground deformation, gas emissions and seismicity are being combined with more advanced models of volcanic flows and their interactions with the environment. In addition more structured and systematic methods for assessing hazards and risk are emerging that allow impartial advice to be given to authorities during volcanic crises. There remain significant issues of how scientific advice and associated uncertainties are communicated to provide effective

  14. Technical Guidance for Hazardous Analysis, Emergency Planning for Extremely Hazardous Substances

    EPA Pesticide Factsheets

    This current guide supplements NRT-1 by providing technical assistance to LEPCs to assess the lethal hazards related to potential airborne releases of extremely hazardous substances (EHSs) as designated under Section 302 of Title Ill of SARA.

  15. Chemical hazards in health care: high hazard, high risk, but low protection.

    PubMed

    McDiarmid, Melissa A

    2006-09-01

    It is counter-intuitive that the healthcare industry, whose mission is the care of the sick, is itself a "high-hazard" industry for the workers it employs. Possessing every hazard class, with chemical agents in the form of pharmaceuticals, sterilants, and germicidals in frequent use, this industry sector consistently demonstrates poor injury and illness statistics, among the highest in the United States, and in the European Union (EU), 34% higher than the average work-related accident rate. In both the United States and the EU, about 10% of all workers are employed in the healthcare sector, and in developing countries as well, forecasts for the increasing need of healthcare workers (HCW) suggests a large population at potential risk of health harm. The explosion of technology growth in the healthcare sector, most obvious in pharmaceutical applications, has not been accompanied by a stepped up safety program in hospitals. Where there is hazard recognition, the remedies are often voluntary, and often poorly enforced. The wrong assumption that this industry would police itself, given its presumed knowledge base, has also been found wanting. The healthcare industry is also a significant waste generator threatening the natural environment with chemical and infectious waste and products of incineration. The ILO has recommended that occupational health goals for industrial nations focus on the hazards of new technology of which pharma and biopharma products are the leaders. This unchecked growth cannot continue without a parallel commitment to the health and safety of workers encountering these "high tech" hazards. Simple strategies to improve the present state include: (a) recognizing healthcare as a "high-hazard" employment sector; (b) fortifying voluntary safety guidelines to the level of enforceable regulation; (c) "potent" inspections; (d) treating hazardous pharmaceuticals like the chemical toxicants they are; and (e) protecting HCWs at least as well as workers in

  16. Association Between Cortisol to DHEA-s Ratio and Sickness Absence in Japanese Male Workers.

    PubMed

    Hirokawa, Kumi; Fujii, Yasuhito; Taniguchi, Toshiyo; Takaki, Jiro; Tsutsumi, Akizumi

    2018-06-01

    This study aimed to investigate the association between serum levels of cortisol and dehydroepiandrosterone sulfate (DHEA-s) and sickness absence over 2 years in Japanese male workers. A baseline survey including questions about health behavior, along with blood sampling for cortisol and DHEA-s, was conducted in 2009. In total, 429 men (mean ± SD age, 52.9 ± 8.6 years) from whom blood samples were collected at baseline were followed until December 31, 2011. The hazard ratios (HR) and 95% confidence intervals (CI) for sickness absence were calculated using a Cox proportional hazard model, adjusted for potential confounders. Among 35 workers who took sickness absences, 31 had physical illness. A high cortisol to DHEA-s ratio increased the risk of sickness absence (crude HR = 2.68, 95% CI 1.12-6.41; adjusted HR = 3.33, 95% CI 1.35-8.20). The cortisol to DHEA-s ratio was linearly associated with an increased risk of sickness absence (p for trend < .050). Single effects of cortisol and DHEA-s levels were not associated with sickness absences. This trend did not change when limited to absences resulting from physical illness. Hormonal conditions related to the hypothalamus-pituitary-adrenocortical axis and adrenal function should be considered when predicting sickness absence. The cortisol to DHEA-s ratio may be more informative than single effects of cortisol and DHEA-s levels.

  17. Tumor-stroma ratio(TSR) as a potential novel predictor of prognosis in digestive system cancers: A meta-analysis.

    PubMed

    Zhang, Runjin; Song, Wei; Wang, Kai; Zou, Shubing

    2017-09-01

    The tumor-stroma ratio (TSR) has been reported as a prognosis predictor in multiple cancers. The aim of this meta-analysis was to investigate the potential value of TSR as a prognostic predictor of cancer in the digestive system. We searched PubMed, Embase, Elsevier and Web of Science. All studies exploring the association of TSR with overall survival (OS) or disease-free survival (DFS), and lymph node metastasis (LNM) were identified. In total, eight studies were eligible for analysis, and they included 1959 patients. Meta-analysis showed that the low TSR in the tumor could predict poor overall survival (OS) in multiple cancers (pooled Hazard Ratio [HR]: 2.15, 95%CI: 1.80-2.57, P<0.00001, fixed effects). For disease-free survival (DFS), low TSR was also a significant predictor (pooled Hazard Ratio [HR]: 2.31, 95%CI: 1.88-2.83, P<0.00001, fixed effects). In addition, low TSR was correlated with tumor stage. The tumor-stroma ratio (TSR) may potentially serve as a poor prognostic predictor for the metastasis and prognosis of cancer. Copyright © 2017. Published by Elsevier B.V.

  18. Passive versus active hazard detection and avoidance systems

    NASA Astrophysics Data System (ADS)

    Neveu, D.; Mercier, G.; Hamel, J.-F.; Simard Bilodeau, V.; Woicke, S.; Alger, M.; Beaudette, D.

    2015-06-01

    Upcoming planetary exploration missions will require advanced guidance, navigation and control technologies to reach landing sites with high precision and safety. Various technologies are currently in development to meet that goal. Some technologies rely on passive sensors and benefit from the low mass and power of such solutions while others rely on active sensors and benefit from an improved robustness and accuracy. This paper presents two different hazard detection and avoidance (HDA) system design approaches. The first architecture relies only on a camera as the passive HDA sensor while the second relies, in addition, on a Lidar as the active HDA sensor. Both options use in common an innovative hazard map fusion algorithm aiming at identifying the safest landing locations. This paper presents the simulation tools and reports the closed-loop software simulation results obtained using each design option. The paper also reports the Monte Carlo simulation campaign that was used to assess the robustness of each design option. The performance of each design option is compared against each other in terms of performance criteria such as percentage of success, mean distance to nearest hazard, etc. The applicability of each design option to planetary exploration missions is also discussed.

  19. Association of Serum Triglyceride to HDL Cholesterol Ratio with All-Cause and Cardiovascular Mortality in Incident Hemodialysis Patients.

    PubMed

    Chang, Tae Ik; Streja, Elani; Soohoo, Melissa; Kim, Tae Woo; Rhee, Connie M; Kovesdy, Csaba P; Kashyap, Moti L; Vaziri, Nosratola D; Kalantar-Zadeh, Kamyar; Moradi, Hamid

    2017-04-03

    Elevated serum triglyceride/HDL cholesterol (TG/HDL-C) ratio has been identified as a risk factor for cardiovascular (CV) disease and mortality in the general population. However, the association of this important clinical index with mortality has not been fully evaluated in patients with ESRD on maintenance hemodialysis (MHD). We hypothesized that the association of serum TG/HDL-C ratio with all-cause and CV mortality in patients with ESRD on MHD is different from the general population. We studied the association of serum TG/HDL-C ratio with all-cause and CV mortality in a nationally representative cohort of 50,673 patients on incident hemodialysis between January 1, 2007 and December 31, 2011. Association of baseline and time-varying TG/HDL-C ratios with mortality was assessed using Cox proportional hazard regression models, with adjustment for multiple variables, including statin therapy. During the median follow-up of 19 months (interquartile range, 11-32 months), 12,778 all-cause deaths and 4541 CV deaths occurred, respectively. We found that the 10th decile group (reference: sixth deciles of TG/HDL-C ratios) had significantly lower risk of all-cause mortality (hazard ratio, 0.91 [95% confidence interval, 0.83 to 0.99] in baseline and 0.86 [95% confidence interval, 0.79 to 0.94] in time-varying models) and CV mortality (hazard ratio, 0.83 [95% confidence interval, 0.72 to 0.96] in baseline and 0.77 [95% confidence interval, 0.66 to 0.90] in time-varying models). These associations remained consistent and significant across various subgroups. Contrary to the general population, elevated TG/HDL-C ratio was associated with better CV and overall survival in patients on hemodialysis. Our findings provide further support that the nature of CV disease and mortality in patients with ESRD is unique and distinct from other patient populations. Hence, it is vital that future studies focus on identifying risk factors unique to patients on MHD and decipher the underlying

  20. Association of Serum Triglyceride to HDL Cholesterol Ratio with All-Cause and Cardiovascular Mortality in Incident Hemodialysis Patients

    PubMed Central

    Chang, Tae Ik; Streja, Elani; Soohoo, Melissa; Kim, Tae Woo; Rhee, Connie M.; Kovesdy, Csaba P.; Kashyap, Moti L.; Vaziri, Nosratola D.; Kalantar-Zadeh, Kamyar

    2017-01-01

    Background and objectives Elevated serum triglyceride/HDL cholesterol (TG/HDL-C) ratio has been identified as a risk factor for cardiovascular (CV) disease and mortality in the general population. However, the association of this important clinical index with mortality has not been fully evaluated in patients with ESRD on maintenance hemodialysis (MHD). We hypothesized that the association of serum TG/HDL-C ratio with all-cause and CV mortality in patients with ESRD on MHD is different from the general population. Design, setting, participants, & measurements We studied the association of serum TG/HDL-C ratio with all-cause and CV mortality in a nationally representative cohort of 50,673 patients on incident hemodialysis between January 1, 2007 and December 31, 2011. Association of baseline and time-varying TG/HDL-C ratios with mortality was assessed using Cox proportional hazard regression models, with adjustment for multiple variables, including statin therapy. Results During the median follow-up of 19 months (interquartile range, 11–32 months), 12,778 all-cause deaths and 4541 CV deaths occurred, respectively. We found that the 10th decile group (reference: sixth deciles of TG/HDL-C ratios) had significantly lower risk of all-cause mortality (hazard ratio, 0.91 [95% confidence interval, 0.83 to 0.99] in baseline and 0.86 [95% confidence interval, 0.79 to 0.94] in time-varying models) and CV mortality (hazard ratio, 0.83 [95% confidence interval, 0.72 to 0.96] in baseline and 0.77 [95% confidence interval, 0.66 to 0.90] in time-varying models). These associations remained consistent and significant across various subgroups. Conclusions Contrary to the general population, elevated TG/HDL-C ratio was associated with better CV and overall survival in patients on hemodialysis. Our findings provide further support that the nature of CV disease and mortality in patients with ESRD is unique and distinct from other patient populations. Hence, it is vital that future

  1. A Windshear Hazard Index

    NASA Technical Reports Server (NTRS)

    Proctor, Fred H.; Hinton, David A.; Bowles, Roland L.

    2000-01-01

    An aircraft exposed to hazardous low-level windshear may suffer a critical loss of airspeed and altitude, thus endangering its ability to remain airborne. In order to characterize this hazard, a nondimensional index was developed based oil aerodynamic principals and understanding of windshear phenomena, 'This paper reviews the development and application of the Bowles F-tactor. which is now used by onboard sensors for the detection of hazardous windshear. It was developed and tested during NASA/I:AA's airborne windshear program and is now required for FAA certification of onboard radar windshear detection systems. Reviewed in this paper are: 1) definition of windshear and description of atmospheric phenomena that may cause hazardous windshear. 2) derivation and discussion of the F-factor. 3) development of the F-factor hazard threshold, 4) its testing during field deployments, and 5) its use in accident reconstructions,

  2. EU landfill waste acceptance criteria and EU Hazardous Waste Directive compliance testing of incinerated sewage sludge ash.

    PubMed

    Donatello, S; Tyrer, M; Cheeseman, C R

    2010-01-01

    A hazardous waste assessment has been completed on ash samples obtained from seven sewage sludge incinerators operating in the UK, using the methods recommended in the EU Hazardous Waste Directive. Using these methods, the assumed speciation of zinc (Zn) ultimately determines if the samples are hazardous due to ecotoxicity hazard. Leaching test results showed that two of the seven sewage sludge ash samples would require disposal in a hazardous waste landfill because they exceed EU landfill waste acceptance criteria for stabilised non-reactive hazardous waste cells for soluble selenium (Se). Because Zn cannot be proven to exist predominantly as a phosphate or oxide in the ashes, it is recommended they be considered as non-hazardous waste. However leaching test results demonstrate that these ashes cannot be considered as inert waste, and this has significant implications for the management, disposal and re-use of sewage sludge ash.

  3. Exploring the effects of driving experience on hazard awareness and risk perception via real-time hazard identification, hazard classification, and rating tasks.

    PubMed

    Borowsky, Avinoam; Oron-Gilad, Tal

    2013-10-01

    This study investigated the effects of driving experience on hazard awareness and risk perception skills. These topics have previously been investigated separately, yet a novel approach is suggested where hazard awareness and risk perception are examined concurrently. Young, newly qualified drivers, experienced drivers, and a group of commercial drivers, namely, taxi drivers performed three consecutive tasks: (1) observed 10 short movies of real-world driving situations and were asked to press a button each time they identified a hazardous situation; (2) observed one of three possible sub-sets of 8 movies (out of the 10 they have seen earlier) for the second time, and were asked to categorize them into an arbitrary number of clusters according to the similarity in their hazardous situation; and (3) observed the same sub-set for a third time and following each movie were asked to rate its level of hazardousness. The first task is considered a real-time identification task while the other two are performed using hindsight. During it participants' eye movements were recorded. Results showed that taxi drivers were more sensitive to hidden hazards than the other driver groups and that young-novices were the least sensitive. Young-novice drivers also relied heavily on materialized hazards in their categorization structure. In addition, it emerged that risk perception was derived from two major components: the likelihood of a crash and the severity of its outcome. Yet, the outcome was rarely considered under time pressure (i.e., in real-time hazard identification tasks). Using hindsight, when drivers were provided with the opportunity to rate the movies' hazardousness more freely (rating task) they considered both components. Otherwise, in the categorization task, they usually chose the severity of the crash outcome as their dominant criterion. Theoretical and practical implications are discussed. Copyright © 2013 Elsevier Ltd. All rights reserved.

  4. Probabilistic Tsunami Hazard Analysis

    NASA Astrophysics Data System (ADS)

    Thio, H. K.; Ichinose, G. A.; Somerville, P. G.; Polet, J.

    2006-12-01

    The recent tsunami disaster caused by the 2004 Sumatra-Andaman earthquake has focused our attention to the hazard posed by large earthquakes that occur under water, in particular subduction zone earthquakes, and the tsunamis that they generate. Even though these kinds of events are rare, the very large loss of life and material destruction caused by this earthquake warrant a significant effort towards the mitigation of the tsunami hazard. For ground motion hazard, Probabilistic Seismic Hazard Analysis (PSHA) has become a standard practice in the evaluation and mitigation of seismic hazard to populations in particular with respect to structures, infrastructure and lifelines. Its ability to condense the complexities and variability of seismic activity into a manageable set of parameters greatly facilitates the design of effective seismic resistant buildings but also the planning of infrastructure projects. Probabilistic Tsunami Hazard Analysis (PTHA) achieves the same goal for hazards posed by tsunami. There are great advantages of implementing such a method to evaluate the total risk (seismic and tsunami) to coastal communities. The method that we have developed is based on the traditional PSHA and therefore completely consistent with standard seismic practice. Because of the strong dependence of tsunami wave heights on bathymetry, we use a full waveform tsunami waveform computation in lieu of attenuation relations that are common in PSHA. By pre-computing and storing the tsunami waveforms at points along the coast generated for sets of subfaults that comprise larger earthquake faults, we can efficiently synthesize tsunami waveforms for any slip distribution on those faults by summing the individual subfault tsunami waveforms (weighted by their slip). This efficiency make it feasible to use Green's function summation in lieu of attenuation relations to provide very accurate estimates of tsunami height for probabilistic calculations, where one typically computes

  5. Probabilistic tsunami hazard assessment in Greece for seismic sources along the segmented Hellenic Arc

    NASA Astrophysics Data System (ADS)

    Novikova, Tatyana; Babeyko, Andrey; Papadopoulos, Gerassimos

    2017-04-01

    Greece and adjacent coastal areas are characterized by a high population exposure to tsunami hazard. The Hellenic Arc is the most active geotectonic structure for the generation of earthquakes and tsunamis. We performed probabilistic tsunami hazard assessment for selected locations of Greek coastlines which are the forecasting points officially used in the tsunami warning operations by the Hellenic National Tsunami Warning Center and the NEAMTWS/IOC/UNESCO. In our analysis we considered seismic sources for tsunami generation along the western, central and eastern segments of the Hellenic Arc. We first created a synthetic catalog as long as 10,000 years for all the significant earthquakes with magnitudes in the range from 6.0 to 8.5, the real events being included in this catalog. For each event included in the synthetic catalog a tsunami was generated and propagated using Boussinesq model. The probability of occurrence for each event was determined by Gutenberg-Richter magnitude-frequency distribution. The results of our study are expressed as hazard curves and hazard maps. The hazard curves were obtained for the selected sites and present the annual probability of exceedance as a function of pick coastal tsunami amplitude. Hazard maps represent the distribution of peak coastal tsunami amplitudes corresponding to a fixed annual probability. In such forms our results can be easily compared to the ones obtained in other studies and further employed for the development of tsunami risk management plans. This research is a contribution to the EU-FP7 tsunami research project ASTARTE (Assessment, Strategy And Risk Reduction for Tsunamis in Europe), grant agreement no: 603839, 2013-10-30.

  6. Updated earthquake catalogue for seismic hazard analysis in Pakistan

    NASA Astrophysics Data System (ADS)

    Khan, Sarfraz; Waseem, Muhammad; Khan, Muhammad Asif; Ahmed, Waqas

    2018-03-01

    A reliable and homogenized earthquake catalogue is essential for seismic hazard assessment in any area. This article describes the compilation and processing of an updated earthquake catalogue for Pakistan. The earthquake catalogue compiled in this study for the region (quadrangle bounded by the geographical limits 40-83° N and 20-40° E) includes 36,563 earthquake events, which are reported as 4.0-8.3 moment magnitude (M W) and span from 25 AD to 2016. Relationships are developed between the moment magnitude and body, and surface wave magnitude scales to unify the catalogue in terms of magnitude M W. The catalogue includes earthquakes from Pakistan and neighbouring countries to minimize the effects of geopolitical boundaries in seismic hazard assessment studies. Earthquakes reported by local and international agencies as well as individual catalogues are included. The proposed catalogue is further used to obtain magnitude of completeness after removal of dependent events by using four different algorithms. Finally, seismicity parameters of the seismic sources are reported, and recommendations are made for seismic hazard assessment studies in Pakistan.

  7. Associations With Eicosapentaenoic Acid to Arachidonic Acid Ratio and Mortality in Hospitalized Heart Failure Patients.

    PubMed

    Watanabe, Shunsuke; Yoshihisa, Akiomi; Kanno, Yuki; Takiguchi, Mai; Yokokawa, Tetsuro; Sato, Akihiko; Miura, Shunsuke; Shimizu, Takeshi; Abe, Satoshi; Sato, Takamasa; Suzuki, Satoshi; Oikawa, Masayoshi; Sakamoto, Nobuo; Yamaki, Takayoshi; Sugimoto, Koichi; Kunii, Hiroyuki; Nakazato, Kazuhiko; Suzuki, Hitoshi; Saitoh, Shu-Ichi; Takeishi, Yasuchika

    2016-12-01

    Intake of n-3 polyunsaturated fatty acids (n-3 PUFAs) lowers the risk of atherosclerotic cardiovascular events, particularly ischemic heart disease. In addition, the ratio of eicosapentaenoic acid (EPA; n-3 PUFA) to arachidonic acid (AA; n-6 PUFA) has recently been recognized as a risk marker of cardiovascular disease. In contrast, the prognostic impact of the EPA/AA ratio on patients with heart failure (HF) remains unclear. A total of 577 consecutive patients admitted for HF were divided into 2 groups based on median of the EPA/AA ratio: low EPA/AA (EPA/AA <0.32 mg/dl, n = 291) and high EPA/AA (EPA/AA ≥0.32, n = 286) groups. We compared laboratory data and echocardiographic findings and followed cardiac mortality. Although body mass index, blood pressure, B-type natriuretic peptide, hemoglobin, estimated glomerular filtration rate, total protein, albumin, sodium, C-reactive protein, and left ventricular ejection fraction did not differ between the 2 groups, cardiac mortality was significantly higher in the low EPA/AA group than in the high EPA/AA group (12.7 vs 5.9%, log-rank P = .004). Multivariate Cox proportional hazard analysis revealed that the EPA/AA ratio was an independent predictor of cardiac mortality (hazard ratio 0.677, 95% confidence interval 0.453-0.983, P = .041) in patients with HF. The EPA/AA ratio was an independent predictor of cardiac mortality in patients with HF; therefore, the prognosis of patients with HF may be improved by taking appropriate management to control the EPA/AA balance. Copyright © 2016 The Author(s). Published by Elsevier Inc. All rights reserved.

  8. Usability Evaluation of a Flight-Deck Airflow Hazard Visualization System

    NASA Technical Reports Server (NTRS)

    Aragon, Cecilia R.

    2004-01-01

    Many aircraft accidents each year are caused by encounters with unseen airflow hazards near the ground, such as vortices, downdrafts, low level wind shear, microbursts, or turbulence from surrounding vegetation or structures near the landing site. These hazards can be dangerous even to airliners; there have been hundreds of fatalities in the United States in the last two decades attributable to airliner encounters with microbursts and low level wind shear alone. However, helicopters are especially vulnerable to airflow hazards because they often have to operate in confined spaces and under operationally stressful conditions (such as emergency search and rescue, military or shipboard operations). Providing helicopter pilots with an augmented-reality display visualizing local airflow hazards may be of significant benefit. However, the form such a visualization might take, and whether it does indeed provide a benefit, had not been studied before our experiment. We recruited experienced military and civilian helicopter pilots for a preliminary usability study to evaluate a prototype augmented-reality visualization system. The study had two goals: first, to assess the efficacy of presenting airflow data in flight; and second, to obtain expert feedback on sample presentations of hazard indicators to refine our design choices. The study addressed the optimal way to provide critical safety information to the pilot, what level of detail to provide, whether to display specific aerodynamic causes or potential effects only, and how to safely and effectively shift the locus of attention during a high-workload task. Three-dimensional visual cues, with varying shape, color, transparency, texture, depth cueing, and use of motion, depicting regions of hazardous airflow, were developed and presented to the pilots. The study results indicated that such a visualization system could be of significant value in improving safety during critical takeoff and landing operations, and also

  9. Thermal co-treatment of combustible hazardous waste and waste incineration fly ash in a rotary kiln.

    PubMed

    Huber, Florian; Blasenbauer, Dominik; Mallow, Ole; Lederer, Jakob; Winter, Franz; Fellner, Johann

    2016-12-01

    As current disposal practices for municipal solid waste incineration (MSWI) fly ash are either associated with significant costs or negative environmental impacts, an alternative treatment was investigated in a field scale experiment. Thereto, two rotary kilns were fed with hazardous waste, and moistened MSWI fly ash (water content of 23%) was added to the fuel of one kiln with a ratio of 169kg/Mg hazardous waste for 54h and 300kg/Mg hazardous waste for 48h while the other kiln was used as a reference. It was shown that the vast majority (>90%) of the inserted MSWI fly ash was transferred to the bottom ash of the rotary kiln. This bottom ash complied with the legal limits for non-hazardous waste landfills, thereby demonstrating the potential of the investigated method to transfer hazardous waste (MSWI fly ash) into non-hazardous waste (bottom ash). The results of a simple mixing test (MSWI fly ash and rotary kiln bottom ash have been mixed accordingly without thermal treatment) revealed that the observed transformation of hazardous MSWI fly ash into non-hazardous bottom ash during thermal co-treatment cannot be referred to dilution, as the mixture did not comply with legal limits for non-hazardous waste landfills. For the newly generated fly ash of the kiln, an increase in the concentration of Cd, K and Pb by 54%, 57% and 22%, respectively, was observed. In general, the operation of the rotary kiln was not impaired by the MSWI fly ash addition. Copyright © 2016 Elsevier Ltd. All rights reserved.

  10. Earthquake Hazard Assessment: Basics of Evaluation

    NASA Astrophysics Data System (ADS)

    Kossobokov, Vladimir

    2016-04-01

    Seismic hazard assessment (SHA) is not an easy task that implies a delicate application of statistics to data of limited size and different accuracy. Earthquakes follow the Unified Scaling Law that generalizes the Gutenberg-Richter relationship by taking into account naturally fractal distribution of their sources. Moreover, earthquakes, including the great and mega events, are clustered in time and their sequences have irregular recurrence intervals. Furthermore, earthquake related observations are limited to the recent most decades (or centuries in just a few rare cases). Evidently, all this complicates reliable assessment of seismic hazard and associated risks. Making SHA claims, either termless or time dependent (so-called t-DASH), quantitatively probabilistic in the frames of the most popular objectivists' viewpoint on probability requires a long series of "yes/no" trials, which cannot be obtained without an extended rigorous testing of the method predictions against real observations. Therefore, we reiterate the necessity and possibility of applying the modified tools of Earthquake Prediction Strategies, in particular, the Error Diagram, introduced by G.M. Molchan in early 1990ies for evaluation of SHA, and the Seismic Roulette null-hypothesis as a measure of the alerted space. The set of errors, i.e. the rates of failure and of the alerted space-time volume, compared to those obtained in the same number of random guess trials permits evaluating the SHA method effectiveness and determining the optimal choice of the parameters in regard to specified cost-benefit functions. These and other information obtained in such a testing supplies us with a realistic estimate of confidence in SHA results and related recommendations on the level of risks for decision making in regard to engineering design, insurance, and emergency management. These basics of SHA evaluation are exemplified in brief with a few examples, which analyses in more detail are given in a poster of

  11. Characterization of the Subsurface Using Vp, Vs, Vp/Vs, and Poisson's Ratio from Body and Surface Waves

    NASA Astrophysics Data System (ADS)

    Catchings, R.

    2017-12-01

    P- and S-wave propagation differ in varying materials in the Earth's crust. As a result, combined measurements of P- and S-wave data can be used to infer properties of the shallow crust, including bulk composition, fluid saturation, faulting and fracturing, seismic velocities, reflectivity, and general structures. Ratios of P- to S-wave velocities and Poisson's ratio, which can be derived from the P- and S-wave data, can be particularly diagnostic of subsurface materials and their physical state. In field studies, S-wave data can be obtained directly with S-wave sources or from surface waves associated with P-wave sources. P- and S-wave data can be processed using reflection, refraction, and surface-wave-analysis methods. With the combined data, unconsolidated sediments, consolidated sediments, and rocks can be differentiated on the basis of seismic velocities and their ratios, as can saturated versus unsaturated sediments. We summarize studies where we have used combined P- and S-wave measurements to reliably map the top of ground water, prospect for minerals, locate subsurface faults, locate basement interfaces, determine basin shapes, and measure shear-wave velocities (with calculated Vs30), and other features of the crust that are important for hazards, engineering, and exploration purposes. When compared directly, we find that body waves provide more accurate measures than surface waves.

  12. 21 CFR 120.7 - Hazard analysis.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Hazard analysis. 120.7 Section 120.7 Food and... hazards. The written hazard analysis shall consist of at least the following: (1) Identification of food..., including food hazards that can occur before, during, and after harvest. The hazard analysis shall be...

  13. 21 CFR 120.7 - Hazard analysis.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 21 Food and Drugs 2 2013-04-01 2013-04-01 false Hazard analysis. 120.7 Section 120.7 Food and... hazards. The written hazard analysis shall consist of at least the following: (1) Identification of food..., including food hazards that can occur before, during, and after harvest. The hazard analysis shall be...

  14. 21 CFR 120.7 - Hazard analysis.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 21 Food and Drugs 2 2011-04-01 2011-04-01 false Hazard analysis. 120.7 Section 120.7 Food and... hazards. The written hazard analysis shall consist of at least the following: (1) Identification of food..., including food hazards that can occur before, during, and after harvest. The hazard analysis shall be...

  15. 21 CFR 120.7 - Hazard analysis.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 21 Food and Drugs 2 2014-04-01 2014-04-01 false Hazard analysis. 120.7 Section 120.7 Food and... hazards. The written hazard analysis shall consist of at least the following: (1) Identification of food..., including food hazards that can occur before, during, and after harvest. The hazard analysis shall be...

  16. Structural estimation of a principal-agent model: moral hazard in medical insurance.

    PubMed

    Vera-Hernández, Marcos

    2003-01-01

    Despite the importance of principal-agent models in the development of modern economic theory, there are few estimations of these models. I recover the estimates of a principal-agent model and obtain an approximation to the optimal contract. The results show that out-of-pocket payments follow a concave profile with respect to costs of treatment. I estimate the welfare loss due to moral hazard, taking into account income effects. I also propose a new measure of moral hazard based on the conditional correlation between contractible and noncontractible variables.

  17. Quantifying Fall-Related Hazards in the Homes of Persons with Glaucoma.

    PubMed

    Yonge, Andrea V; Swenor, Bonnielin K; Miller, Rhonda; Goldhammer, Victoria; West, Sheila K; Friedman, David S; Gitlin, Laura N; Ramulu, Pradeep Y

    2017-04-01

    To characterize fall-related hazards in the homes of persons with suspected or diagnosed glaucoma, and to determine whether those with worse visual field (VF) damage have fewer home hazards. Cross-sectional study using baseline (2013-2015) data from the ongoing Falls in Glaucoma Study (FIGS). One-hundred seventy-four of 245 (71.0%) FIGS participants agreeing to the home assessment. Participants' homes were assessed using the Home Environment Assessment for the Visually Impaired (HEAVI). A single evaluator assessed up to 127 potential hazards in 8 home regions. In the clinic, binocular contrast sensitivity (CS) and better-eye visual acuity (VA) were evaluated, and 24-2 VFs were obtained to calculate average integrated VF (IVF) sensitivity. Total number of home hazards. No significant visual or demographic differences were noted between participants who did and did not complete the home assessment (P > 0.09 for all measures). Mean age among those completing the home assessment (n = 174) was 71.1 years, and IVF sensitivity ranged from 5.6 to 33.4 dB (mean = 27.2 dB, standard deviation [SD] = 4.0 dB). The mean number of items graded per home was 85.2 (SD = 13.2), and an average of 32.7 (38.3%) were identified as hazards. IVF sensitivity, CS, and VA were not associated with total home hazards or the number of hazards in any given room (P > 0.06 for all visual measures and rooms). The bathroom contained the greatest number of hazards (mean = 7.9; 54.2% of graded items classified as hazardous), and the most common hazards identified in at least 1 room were ambient lighting <300 lux and exposed light bulbs. Only 27.9% of graded rooms had adequate lighting. IVF sensitivity, CS, and VA were not associated with home lighting levels (P > 0.18 for all), but brighter room lighting was noted in the homes of participants with higher median income (P < 0.001). Multiple home fall hazards were identified in the study population, and hazard numbers were not lower for persons with

  18. Social vulnerability of rural households to flood hazards in western mountainous regions of Henan province, China

    NASA Astrophysics Data System (ADS)

    Liu, Delin; Li, Yue

    2016-05-01

    Evaluating social vulnerability is a crucial issue in risk and disaster management. In this study, a household social vulnerability index (HSVI) to flood hazards was developed and used to assess the social vulnerability of rural households in western mountainous regions of Henan province, China. Eight key indicators were identified using existing literature and discussions with experts from multiple disciplines and local farmers, and their weights were determined using principle component analysis (PCA) and an expert scoring method. The results showed that (1) the ratio of perennial work in other places, hazard-related training and illiteracy ratio (15+) were the most dominant factors of social vulnerability. (2) The numbers of high, moderate and low vulnerability households were 14, 64 and 16, respectively, which accounted for 14.9, 68.1 and 17.0 % of the total interviewed rural households, respectively. (3) The correlation coefficient between household social vulnerability scores and casualties in a storm flood in July 2010 was significant at 0.05 significance level (r = 0.748), which indicated that the selected indicators and their weights were valid. (4) Some mitigation strategies to reduce household social vulnerability to flood hazards were proposed, which included (1) improving the local residents' income and their disaster-related knowledge and evacuation skills, (2) developing emergency plans and carrying out emergency drills and training, (3) enhancing the accuracy of disaster monitoring and warning systems and (4) establishing a specific emergency management department and comprehensive rescue systems. These results can provide useful information for rural households and local governments to prepare, mitigate and respond to flood hazards, and the corresponding strategies can help local households to reduce their social vulnerability and improve their ability to resist flood hazard.

  19. 78 FR 38730 - Announcement of Funding Awards for Lead-Based Paint Hazard Control, and Lead Hazard Reduction...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-06-27

    ... Awards for Lead-Based Paint Hazard Control, and Lead Hazard Reduction Demonstration Grant Programs for... (OHHLHC) Lead-Based Paint Hazard Control, and Lead Hazard Reduction Demonstration Grant Program Notices of... Grants.gov on December 3, 2012, and amended on January 18, 2013, for the Lead Based Paint Hazard Control...

  20. Neutrophil-to-lymphocyte ratio in head and neck cancer prognosis: A systematic review and meta-analysis.

    PubMed

    Mascarella, Marco A; Mannard, Erin; Silva, Sabrina Daniela; Zeitouni, Anthony

    2018-05-01

    Hematologic markers, such as the neutrophil-to-lymphocyte ratio (NLR), characterize the inflammatory response to cancer and are associated with poorer survival in various malignancies. We evaluate the effect of pretreatment NLR on overall survival (OS) in patients with head and neck squamous cell carcinoma (HNSCC). Using multiple databases, a systematic search for articles evaluating the effect of NLR on OS in patients with HNSCC was performed. An inverse variation, random-effects model was used to analyze the data. A total of 24 of 241 articles, including 6479 patients, were analyzed. The combined hazard ratio for OS in patients with an elevated NLR (range 2.04-5) was 1.78 (confidence interval [CI] 1.53-2.07; P < .0001). The hazard ratios for site-specific cancer: oral cavity 1.56 CI 1.23-1.98 (P < .001), nasopharynx 1.66 CI 1.35-2.04 (P < .001), larynx 1.55 CI 1.26-1.92 (P < .001), and hypopharynx 2.36 CI 1.54-3.61 (P < .001). An elevated NLR is predictive of poorer OS in patients with HNSCC. © 2018 Wiley Periodicals, Inc.

  1. Hazardous materials regulation in Virginia.

    DOT National Transportation Integrated Search

    1987-01-01

    The report covered four subjects: (1) significance of hazardous materials in Virginia, (2) federal regulation, (3) laws on the transport of hazardous materials in Virginia, and (4) Virginia regulations on hazardous materials emergency response.

  2. A Gis Model Application Supporting The Analysis of The Seismic Hazard For The Urban Area of Catania (italy)

    NASA Astrophysics Data System (ADS)

    Grasso, S.; Maugeri, M.

    After the Summit held in Washington on August 20-22 2001 to plan the first World Conference on the mitigation of Natural Hazards, a Group for the analysis of Natural Hazards within the Mediterranean area has been formed. The Group has so far determined the following hazards: (1) Seismic hazard (hazard for historical buildings included); (2) Hazard linked to the quantity and quality of water; (3) Landslide hazard; (4) Volcanic hazard. The analysis of such hazards implies the creation and the management of data banks, which can only be used if the data are properly geo-settled to allow a crossed use of them. The obtained results must be therefore represented on geo-settled maps. The present study is part of a research programme, namely "Detailed Scenarios and Actions for Seismic Prevention of Damage in the Urban Area of Catania", financed by the National Department for the Civil Protection and the National Research Council-National Group for the Defence Against Earthquakes (CNR-GNDT). Nowadays the south-eastern area of Sicily, called the "Iblea" seismic area of Sicily, is considered as one of the most intense seismic zones in Italy, based on the past and current seismic history and on the typology of civil buildings. Safety against earthquake hazards has two as pects: structural safety against potentially destructive dynamic forces and site safety related to geotechnical phenomena such as amplification, land sliding and soil liquefaction. So the correct evaluation of seismic hazard is highly affected by risk factors due to geological nature and geotechnical properties of soils. The effect of local geotechnical conditions on damages suffered by buildings under seismic conditions has been widely recognized, as it is demonstrated by the Manual for Zonation on Seismic Geotechnical Hazards edited by the International Society for Soil Mechanics and Geotechnical Engineering (TC4, 1999). The evaluation of local amplification effects may be carried out by means of either

  3. Understanding earthquake hazards in urban areas - Evansville Area Earthquake Hazards Mapping Project

    USGS Publications Warehouse

    Boyd, Oliver S.

    2012-01-01

    The region surrounding Evansville, Indiana, has experienced minor damage from earthquakes several times in the past 200 years. Because of this history and the proximity of Evansville to the Wabash Valley and New Madrid seismic zones, there is concern among nearby communities about hazards from earthquakes. Earthquakes currently cannot be predicted, but scientists can estimate how strongly the ground is likely to shake as a result of an earthquake and are able to design structures to withstand this estimated ground shaking. Earthquake-hazard maps provide one way of conveying such information and can help the region of Evansville prepare for future earthquakes and reduce earthquake-caused loss of life and financial and structural loss. The Evansville Area Earthquake Hazards Mapping Project (EAEHMP) has produced three types of hazard maps for the Evansville area: (1) probabilistic seismic-hazard maps show the ground motion that is expected to be exceeded with a given probability within a given period of time; (2) scenario ground-shaking maps show the expected shaking from two specific scenario earthquakes; (3) liquefaction-potential maps show how likely the strong ground shaking from the scenario earthquakes is to produce liquefaction. These maps complement the U.S. Geological Survey's National Seismic Hazard Maps but are more detailed regionally and take into account surficial geology, soil thickness, and soil stiffness; these elements greatly affect ground shaking.

  4. NASA LaRC Hazardous Material Pharmacy

    NASA Technical Reports Server (NTRS)

    Esquenet, Remy

    1995-01-01

    In 1993-1994 the Office of Environmental Engineering contracted SAIC to develop NASA Langley's Pollution Prevention (P2) Program. One of the priority projects identified in this contract was the development of a hazardous waste minimization (HAZMIN)/hazardous materials reutilization (HAZMART) program in the form of a Hazardous Materials Pharmacy. A hazardous materials pharmacy is designed to reduce hazardous material procurement costs and hazardous waste disposal costs. This is accomplished through the collection and reissue of excess hazardous material. Currently, a rarely used hazardous material may be stored in a shop area, unused, until it passes its expiration date. The material is then usually disposed of as a hazardous waste, often at a greater expense than the original cost of the material. While this material was on the shelf expiring, other shop areas may have ordered new supplies of the same material. The hazardous material pharmacy would act as a clearinghouse for such materials. Material that is not going to be used would be turned in to the pharmacy. Other users could then be issued this material free of charge, thereby reducing procurement costs. The use of this material by another shop prevents it from expiring, thereby reducing hazardous waste disposal costs.

  5. Seismic hazard assessment: Issues and alternatives

    USGS Publications Warehouse

    Wang, Z.

    2011-01-01

    Seismic hazard and risk are two very important concepts in engineering design and other policy considerations. Although seismic hazard and risk have often been used inter-changeably, they are fundamentally different. Furthermore, seismic risk is more important in engineering design and other policy considerations. Seismic hazard assessment is an effort by earth scientists to quantify seismic hazard and its associated uncertainty in time and space and to provide seismic hazard estimates for seismic risk assessment and other applications. Although seismic hazard assessment is more a scientific issue, it deserves special attention because of its significant implication to society. Two approaches, probabilistic seismic hazard analysis (PSHA) and deterministic seismic hazard analysis (DSHA), are commonly used for seismic hazard assessment. Although PSHA has been pro-claimed as the best approach for seismic hazard assessment, it is scientifically flawed (i.e., the physics and mathematics that PSHA is based on are not valid). Use of PSHA could lead to either unsafe or overly conservative engineering design or public policy, each of which has dire consequences to society. On the other hand, DSHA is a viable approach for seismic hazard assessment even though it has been labeled as unreliable. The biggest drawback of DSHA is that the temporal characteristics (i.e., earthquake frequency of occurrence and the associated uncertainty) are often neglected. An alternative, seismic hazard analysis (SHA), utilizes earthquake science and statistics directly and provides a seismic hazard estimate that can be readily used for seismic risk assessment and other applications. ?? 2010 Springer Basel AG.

  6. 29 CFR 1917.25 - Fumigants, pesticides, insecticides and hazardous preservatives (see also § 1917.2 Hazardous...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... preservatives (see also § 1917.2 Hazardous cargo, material, substance or atmosphere). 1917.25 Section 1917.25..., insecticides and hazardous preservatives (see also § 1917.2 Hazardous cargo, material, substance or atmosphere... treat cargo shall be: (1) Appropriate for the hazard involved; (2) Conducted by designated persons; and...

  7. 29 CFR 1917.25 - Fumigants, pesticides, insecticides and hazardous preservatives (see also § 1917.2 Hazardous...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... preservatives (see also § 1917.2 Hazardous cargo, material, substance or atmosphere). 1917.25 Section 1917.25..., insecticides and hazardous preservatives (see also § 1917.2 Hazardous cargo, material, substance or atmosphere... treat cargo shall be: (1) Appropriate for the hazard involved; (2) Conducted by designated persons; and...

  8. 29 CFR 1917.25 - Fumigants, pesticides, insecticides and hazardous preservatives (see also § 1917.2 Hazardous...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... preservatives (see also § 1917.2 Hazardous cargo, material, substance or atmosphere). 1917.25 Section 1917.25..., insecticides and hazardous preservatives (see also § 1917.2 Hazardous cargo, material, substance or atmosphere... treat cargo shall be: (1) Appropriate for the hazard involved; (2) Conducted by designated persons; and...

  9. 29 CFR 1917.25 - Fumigants, pesticides, insecticides and hazardous preservatives (see also § 1917.2 Hazardous...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... preservatives (see also § 1917.2 Hazardous cargo, material, substance or atmosphere). 1917.25 Section 1917.25..., insecticides and hazardous preservatives (see also § 1917.2 Hazardous cargo, material, substance or atmosphere... treat cargo shall be: (1) Appropriate for the hazard involved; (2) Conducted by designated persons; and...

  10. 29 CFR 1917.25 - Fumigants, pesticides, insecticides and hazardous preservatives (see also § 1917.2 Hazardous...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... preservatives (see also § 1917.2 Hazardous cargo, material, substance or atmosphere). 1917.25 Section 1917.25..., insecticides and hazardous preservatives (see also § 1917.2 Hazardous cargo, material, substance or atmosphere... treat cargo shall be: (1) Appropriate for the hazard involved; (2) Conducted by designated persons; and...

  11. Hazard Analysis Guidelines for Transit Projects

    DOT National Transportation Integrated Search

    2000-01-01

    These hazard analysis guidelines discuss safety critical systems and subsystems, types of hazard analyses, when hazard analyses should be performed, and the hazard analysis philosophy. These guidelines are published by FTA to assist the transit indus...

  12. Explosion Hazards Associated with Spills of Large Quantities of Hazardous Materials. Phase I

    DTIC Science & Technology

    1974-10-01

    quantities of hazardous material such as liquified natural gas ( LNG ), liquified petroleum gils (LPG), or ethylene. The principal results are (1) a...associated with spills of large quantities of hazardous material such as liquified natural gas ( LNG ), liquified petroleum gas (LPG), or ethylene. The...liquified natural gas ( LNG ). Unfortunately, as the quantity of material shipped at one time increases, so does the potential hazard associated with

  13. Final Hazard Search

    NASA Image and Video Library

    2015-07-08

    This single frame from a four-frame movie shows New Horizons' final deep search for hazardous material around Pluto, obtained on July 1, 2015. These data allow a highly sensitive search for any new moons. The images were taken with the spacecraft's Long Range Reconnaissance Imager (LORRI) over a 100-minute period, and were the final observations in the series of dedicated searches for hazards in the Pluto system which began on May 11. The images show all five known satellites of Pluto moving in their orbits around the dwarf planet, but analysis of these data has so far not revealed the existence of any additional moons. This means that any undiscovered Plutonian moons further than a few thousand miles from Pluto must be smaller than about 1 mile (1.6 kilometers) in diameter, if their surfaces have similar brightness to Pluto's big moon Charon. For comparison, Pluto's faintest known moon, Styx, which is conspicuous in the lower left quadrant of these images, is about 4 miles (7 kilometers) across, assuming the same surface brightness. The absence of additional moons, and also the absence of detectable rings in the hazard search data, imply that the spacecraft is very unlikely to be damaged by collisions with rings, or dust particles ejected from moons, during its high-speed passage through the Pluto system. The four movie frames were taken at 16:28, 16:38, 17:52, and 18:04 UTC on July 1, from a range of 9.4 million miles (15.2 million kilometers). Each frame is a mosaic of four sets of overlapping images, with a total exposure time of 120 seconds. The images have been heavily processed to remove the glare of Pluto and Charon, and the dense background of stars, though blemishes remain at the locations of many of the brighter stars. The "tails" extending to the right or downward from Pluto and Charon are camera artifacts caused by the extreme overexposure of both objects. Pluto and its five moons Charon, Styx, Nix, Kerberos and Hydra are identified by their initials

  14. 78 FR 42998 - Hazardous Materials: Improving the Safety of Railroad Transportation of Hazardous Materials

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-18

    ... Materials: Improving the Safety of Railroad Transportation of Hazardous Materials AGENCY: Pipeline and... that affect the safety of the transportation of hazardous materials by rail and are seeking input from... authority to FRA. 49 CFR 1.89(a) through (q). The Federal hazardous materials transportation laws, 49 U.S.C...

  15. Applications of a Forward-Looking Interferometer for the On-board Detection of Aviation Weather Hazards

    NASA Technical Reports Server (NTRS)

    West, Leanne; Gimmestad, Gary; Smith, William; Kireev, Stanislav; Cornman, Larry B.; Schaffner, Philip R.; Tsoucalas, George

    2008-01-01

    The Forward-Looking Interferometer (FLI) is a new instrument concept for obtaining measurements of potential weather hazards to alert flight crews. The FLI concept is based on high-resolution Infrared (IR) Fourier Transform Spectrometry (FTS) technologies that have been developed for satellite remote sensing, and which have also been applied to the detection of aerosols and gases for other purposes. It is being evaluated for multiple hazards including clear air turbulence (CAT), volcanic ash, wake vortices, low slant range visibility, dry wind shear, and icing, during all phases of flight. Previous sensitivity and characterization studies addressed the phenomenology that supports detection and mitigation by the FLI. Techniques for determining the range, and hence warning time, were demonstrated for several of the hazards, and a table of research instrument parameters was developed for investigating all of the hazards discussed above. This work supports the feasibility of detecting multiple hazards with an FLI multi-hazard airborne sensor, and for producing enhanced IR images in reduced visibility conditions; however, further research must be performed to develop a means to estimate the intensities of the hazards posed to an aircraft and to develop robust algorithms to relate sensor measurables to hazard levels. In addition, validation tests need to be performed with a prototype system.

  16. Hazard Identification and Risk Assessment in Water Treatment Plant considering Environmental Health and Safety Practice

    NASA Astrophysics Data System (ADS)

    Falakh, Fajrul; Setiani, Onny

    2018-02-01

    Water Treatment Plant (WTP) is an important infrastructure to ensure human health and the environment. In its development, aspects of environmental safety and health are of concern. This paper case study was conducted at the Water Treatment Plant Company in Semarang, Central Java, Indonesia. Hazard identification and risk assessment is one part of the occupational safety and health program at the risk management stage. The purpose of this study was to identify potential hazards using hazard identification methods and risk assessment methods. Risk assessment is done using criteria of severity and probability of accident. The results obtained from this risk assessment are 22 potential hazards present in the water purification process. Extreme categories that exist in the risk assessment are leakage of chlorine and industrial fires. Chlorine and fire leakage gets the highest value because its impact threatens many things, such as industrial disasters that could endanger human life and the environment. Control measures undertaken to avoid potential hazards are to apply the use of personal protective equipment, but management will also be better managed in accordance with hazard control hazards, occupational safety and health programs such as issuing work permits, emergency response training is required, Very useful in overcoming potential hazards that have been determined.

  17. Resilience to Interacting multi-natural hazards

    NASA Astrophysics Data System (ADS)

    Zhuo, Lu; Han, Dawei

    2016-04-01

    Conventional analyses of hazard assessment tend to focus on individual hazards in isolation. However, many parts of the world are usually affected by multiple natural hazards with the potential for interacting relationships. The understanding of such interactions, their impacts and the related uncertainties, are an important and topical area of research. Interacting multi-hazards may appear in different forms, including 1) CASCADING HAZARDS (a primary hazard triggering one or more secondary hazards such as an earthquake triggering landslides which may block river channels with dammed lakes and ensued floods), 2) CONCURRING HAZARDS (two or more primary hazards coinciding to trigger or exacerbate secondary hazards such as an earthquake and a rainfall event simultaneously creating landslides), and 3) ALTERING HAZARDS (a primary hazard increasing the probability of a secondary hazard occurring such as major earthquakes disturbing soil/rock materials by violent ground shaking which alter the regional patterns of landslides and debris flows in the subsequent years to come). All three types of interacting multi-hazards may occur in natural hazard prone regions, so it is important that research on hazard resilience should cover all of them. In the past decades, great progresses have been made in tackling disaster risk around the world. However, there are still many challenging issues to be solved, and the disasters over recent years have clearly demonstrated the inadequate resilience in our highly interconnected and interdependent systems. We have identified the following weaknesses and knowledge gaps in the current disaster risk management: 1) although our understanding in individual hazards has been greatly improved, there is a lack of sound knowledge about mechanisms and processes of interacting multi-hazards. Therefore, the resultant multi-hazard risk is often significantly underestimated with severe consequences. It is also poorly understood about the spatial and

  18. Probabilistic seismic hazard analysis for a nuclear power plant site in southeast Brazil

    NASA Astrophysics Data System (ADS)

    de Almeida, Andréia Abreu Diniz; Assumpção, Marcelo; Bommer, Julian J.; Drouet, Stéphane; Riccomini, Claudio; Prates, Carlos L. M.

    2018-05-01

    A site-specific probabilistic seismic hazard analysis (PSHA) has been performed for the only nuclear power plant site in Brazil, located 130 km southwest of Rio de Janeiro at Angra dos Reis. Logic trees were developed for both the seismic source characterisation and ground-motion characterisation models, in both cases seeking to capture the appreciable ranges of epistemic uncertainty with relatively few branches. This logic-tree structure allowed the hazard calculations to be performed efficiently while obtaining results that reflect the inevitable uncertainty in long-term seismic hazard assessment in this tectonically stable region. An innovative feature of the study is an additional seismic source zone added to capture the potential contributions of characteristics earthquake associated with geological faults in the region surrounding the coastal site.

  19. Arcjet nozzle area ratio effects

    NASA Technical Reports Server (NTRS)

    Curran, Francis M.; Sarmiento, Charles J.; Birkner, Bjorn W.; Kwasny, James

    1990-01-01

    An experimental investigation was conducted to determine the effect of nozzle area ratio on the operating characteristics and performance of a low power dc arcjet thruster. Conical thoriated tungsten nozzle inserts were tested in a modular laboratory arcjet thruster run on hydrogen/nitrogen mixtures simulating the decomposition products of hydrazine. The converging and diverging sides of the inserts had half angles of 30 and 20 degrees, respectively, similar to a flight type unit currently under development. The length of the diverging side was varied to change the area ratio. The nozzle inserts were run over a wide range of specific power. Current, voltage, mass flow rate, and thrust were monitored to provide accurate comparisons between tests. While small differences in performance were observed between the two nozzle inserts, it was determined that for each nozzle insert, arcjet performance improved with increasing nozzle area ratio to the highest area ratio tested and that the losses become very pronounced for area ratios below 50. These trends are somewhat different than those obtained in previous experimental and analytical studies of low Re number nozzles. It appears that arcjet performance can be enhanced via area ratio optimization.

  20. Arcjet Nozzle Area Ratio Effects

    NASA Technical Reports Server (NTRS)

    Curran, Francis M.; Sarmiento, Charles J.; Birkner, Bjorn W.; Kwasny, James

    1990-01-01

    An experimental investigation was conducted to determine the effect of nozzle area ratio on the operating characteristics and performance of a low power dc arcjet thruster. Conical thoriated tungsten nozzle inserts were tested in a modular laboratory arcjet thruster run on hydrogen/nitrogen mixtures simulating the decomposition products of hydrazine. The converging and diverging sides of the inserts had half angles of 30 and 20 degrees, respectively, similar to a flight type unit currently under development. The length of the diverging side was varied to change the area ratio. The nozzle inserts were run over a wide range of specific power. Current, voltage, mass flow rate, and thrust were monitored to provide accurate comparisons between tests. While small differences in performance were observed between the two nozzle inserts, it was determined that for each nozzle insert, arcjet performance improved with increasing nozzle area ratio to the highest area ratio tested and that the losses become very pronounced for area ratios below 50. These trends are somewhat different than those obtained in previous experimental and analytical studies of low Re number nozzles. It appears that arcjet performance can be enhanced via area ratio optimization.

  1. Moral hazard.

    PubMed

    Chambers, David W

    2009-01-01

    Civil societies set aside a common pool of resources to help those with whom chance has dealt harshly. Frequently we allow access to these common resources when bad luck is assisted by foolishness and lack of foresight. Sometimes we may even help ourselves to a few of those common assets since others are doing so and they are public goods, the cost of which is shared and has already been paid. Moral hazard is the questionable ethical practice of increasing opportunity for individual gain while shifting risk for loss to the group. Bailout is an example. What makes moral hazard so widespread and difficult to manage is that it is easier for individuals to see their advantage than it is for groups to see theirs. Runaway American healthcare costs can be explained in these terms. Cheating, overtreatment, commercialism, and other moral problems in dentistry can be traced to the interaction between opportunistic individual behavior and permissive group responses common in moral hazard.

  2. Hazards in the theater.

    PubMed

    Rossol, M; Hinkamp, D

    2001-01-01

    The authors offer a survey of the myriad and unique safety and health hazards faced past and present by performers and theatrical workers, from preproduction work, through the show, and during the strike (dismantling). Special emphasis is given to health hazards posed by the many new plastic resin systems and adhesives used in set, prop, and costume construction; the hazards of special-effect fogs, smokes, haze, dusts, and pyrotechnic emissions; and theatrical makeup.

  3. The Improved Estimation of Ratio of Two Population Proportions

    ERIC Educational Resources Information Center

    Solanki, Ramkrishna S.; Singh, Housila P.

    2016-01-01

    In this article, first we obtained the correct mean square error expression of Gupta and Shabbir's linear weighted estimator of the ratio of two population proportions. Later we suggested the general class of ratio estimators of two population proportions. The usual ratio estimator, Wynn-type estimator, Singh, Singh, and Kaur difference-type…

  4. St. Louis area earthquake hazards mapping project; seismic and liquefaction hazard maps

    USGS Publications Warehouse

    Cramer, Chris H.; Bauer, Robert A.; Chung, Jae-won; Rogers, David; Pierce, Larry; Voigt, Vicki; Mitchell, Brad; Gaunt, David; Williams, Robert; Hoffman, David; Hempen, Gregory L.; Steckel, Phyllis; Boyd, Oliver; Watkins, Connor M.; Tucker, Kathleen; McCallister, Natasha

    2016-01-01

    We present probabilistic and deterministic seismic and liquefaction hazard maps for the densely populated St. Louis metropolitan area that account for the expected effects of surficial geology on earthquake ground shaking. Hazard calculations were based on a map grid of 0.005°, or about every 500 m, and are thus higher in resolution than any earlier studies. To estimate ground motions at the surface of the model (e.g., site amplification), we used a new detailed near‐surface shear‐wave velocity model in a 1D equivalent‐linear response analysis. When compared with the 2014 U.S. Geological Survey (USGS) National Seismic Hazard Model, which uses a uniform firm‐rock‐site condition, the new probabilistic seismic‐hazard estimates document much more variability. Hazard levels for upland sites (consisting of bedrock and weathered bedrock overlain by loess‐covered till and drift deposits), show up to twice the ground‐motion values for peak ground acceleration (PGA), and similar ground‐motion values for 1.0 s spectral acceleration (SA). Probabilistic ground‐motion levels for lowland alluvial floodplain sites (generally the 20–40‐m‐thick modern Mississippi and Missouri River floodplain deposits overlying bedrock) exhibit up to twice the ground‐motion levels for PGA, and up to three times the ground‐motion levels for 1.0 s SA. Liquefaction probability curves were developed from available standard penetration test data assuming typical lowland and upland water table levels. A simplified liquefaction hazard map was created from the 5%‐in‐50‐year probabilistic ground‐shaking model. The liquefaction hazard ranges from low (60% of area expected to liquefy) in the lowlands. Because many transportation routes, power and gas transmission lines, and population centers exist in or on the highly susceptible lowland alluvium, these areas in the St. Louis region are at significant potential risk from seismically induced liquefaction and associated

  5. The Association between Triglyceride/High-Density Lipoprotein Cholesterol Ratio and All-Cause Mortality in Acute Coronary Syndrome after Coronary Revascularization

    PubMed Central

    Wan, Ke; Zhao, Jianxun; Huang, Hao; Zhang, Qing; Chen, Xi; Zeng, Zhi; Zhang, Li; Chen, Yucheng

    2015-01-01

    Aims High triglycerides (TG) and low high-density lipoprotein cholesterol (HDL-C) are cardiovascular risk factors. A positive correlation between elevated TG/HDL-C ratio and all-cause mortality and cardiovascular events exists in women. However, utility of TG to HDL-C ratio for prediction is unknown among acute coronary syndrome (ACS). Methods Fasting lipid profiles, detailed demographic data, and clinical data were obtained at baseline from 416 patients with ACS after coronary revascularization. Subjects were stratified into three levels of TG/HDL-C. We constructed multivariate Cox-proportional hazard models for all-cause mortality over a median follow-up of 3 years using log TG to HDL-C ratio as a predictor variable and analyzing traditional cardiovascular risk factors. We constructed a logistic regression model for major adverse cardiovascular events (MACEs) to prove that the TG/HDL-C ratio is a risk factor. Results The subject’s mean age was 64 ± 11 years; 54.5% were hypertensive, 21.8% diabetic, and 61.0% current or prior smokers. TG/HDL-C ratio ranged from 0.27 to 14.33. During the follow-up period, there were 43 deaths. In multivariate Cox models after adjusting for age, smoking, hypertension, diabetes, and severity of angiographic coronary disease, patients in the highest tertile of ACS had a 5.32-fold increased risk of mortality compared with the lowest tertile. After adjusting for conventional coronary heart disease risk factors by the logistic regression model, the TG/HDL-C ratio was associated with MACEs. Conclusion The TG to HDL-C ratio is a powerful independent predictor of all-cause mortality and is a risk factor of cardiovascular events. PMID:25880982

  6. Landslide hazard assessment of the Black sea coastline (Caucasus, Russia) via drones

    NASA Astrophysics Data System (ADS)

    Kazeev, Andrey; Postoev, German; Fedotova, Ksenia

    2017-04-01

    Landslide hazard assessment of slopes of Sochi was performed along the railway between the cities Tuapse and Adler (total length 103 km). The railway passes through the territory with active development of hazardous geological processes such as landslides, rock falls and debris-flows. By the beginning of 2016, 36 landslide sites were discovered along the railway (total length 34 km), 48 rock-fall sites (length 31 km), and 5 debris-flow sites (length 0.14 km). In recent years the intensification of deformations was observed. For instance, during previous 10 years (1996¬¬-2005) 28 sudden deformations occurred due to slope processes, which caused interruptions in traffic. And in the present decade (2006-2015), 72 deformations were recorded. High landslide activity and economic loss determined the necessity of complex investigations of engineering geological conditions of landslides development and causes of its intensification. The protection strategy development was needed to minimize negative consequences. Thus, the investigations of landslide situation along the railway "Tuapse - Adler" included the categorization of landslide sites by level of hazard, with risk assessment based on numerical criteria. Preliminary evaluation of landslide hazard for the railway was conducted via the analysis of archived engineering-geological documents. 13 of 36 landslide sites (total length 13 km) were selected, reflecting the variety and peculiarities of landslide displacements on slopes (both active and inactive sites). Visual field observations of landslide slopes using drone "DJI Phantom 4" were completed during the second stage of this investigation. High-resolution photographs of landslide cirques, cracks, scarp walls, vegetation features were obtained via drone, which would have been impossible to obtain from the ground in conditions of dense subtropical vegetation cover. Possible approaches to the landslide activity and hazard assessment were evaluated: slope stability

  7. 21 CFR 123.6 - Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 21 Food and Drugs 2 2012-04-01 2012-04-01 false Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan. 123.6 Section 123.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... processor shall have and implement a written HACCP plan whenever a hazard analysis reveals one or more food...

  8. 21 CFR 123.6 - Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan. 123.6 Section 123.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF... processor shall have and implement a written HACCP plan whenever a hazard analysis reveals one or more food...

  9. 76 FR 37283 - Hazardous Materials: Revision to the List of Hazardous Substances and Reportable Quantities

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-06-27

    ... DEPARTMENT OF TRANSPORTATION Pipeline and Hazardous Materials Safety Administration 49 CFR Part... under the Federal hazardous materials transportation law (49 U.S.C. 5101-5128). PHMSA carries out the rulemaking responsibilities of the Secretary of Transportation under the Federal hazardous materials...

  10. Hazardous Waste: Cleanup and Prevention.

    ERIC Educational Resources Information Center

    Vandas, Steve; Cronin, Nancy L.

    1996-01-01

    Discusses hazardous waste, waste disposal, unsafe exposure, movement of hazardous waste, and the Superfund clean-up process that consists of site discovery, site assessment, clean-up method selection, site clean up, and site maintenance. Argues that proper disposal of hazardous waste is everybody's responsibility. (JRH)

  11. Diffuse-direct ultraviolet ratios with a compact double monochromator

    NASA Technical Reports Server (NTRS)

    Garrison, L. M.; Murray, L. E.; Doda, D. D.; Green, A. E. S.

    1978-01-01

    An improved system has been implemented for measuring the ratio of the diffuse skylight to the direct sunlight in the biologically active region of the UV near the atmospheric limit. It combines a double monochromator employing holographic gratings for reduction of stray light with a cooled photomultiplier tube to provide a greatly improved SNR below 300 nm. Data may be obtained in either a scan mode or a narrowband photometry mode; in the latter mode accurate ratios have been obtained near 290 nm. Representative data are discussed along with a theoretical model of the ratio. The system is compact enough for use in a mobile monitoring system.

  12. Impact of graft-to-recipient weight ratio on small-for-size syndrome following living donor liver transplantation.

    PubMed

    Bell, Richard; Pandanaboyana, Sanjay; Upasani, Vivek; Prasad, Raj

    2018-05-01

    This meta-analysis aimed to compare living donor liver transplantation (LDLT) grafts with a graft-to-recipient weight ratio (GRWR) of <0.8 to grafts with a GRWR ≥0.8 with regards to small-for-size syndrome (SFSS) and short and longer term outcomes. An electronic search was performed of the MEDLINE, EMBASE and PubMed databases until December 2016 using both subject headings (MeSH) and free text. Pooled odds ratios and hazard ratios were calculated using fixed- and random-effects models for meta-analysis. Eight studies including 1833 patients met the inclusion criteria. The rate of SFSS was 10% in the <0.8 group and 5% in the ≥0.8 group (odds ratio: 1.69 (1.09, 2.61) (P = 0.020)). No significant difference was noted between the two groups with regards to graft survival up to 5 years (hazard ratio: 1.31 (0.88, 1.94) (P = 0.190)). Similarly, no significant difference was noted in overall complications (P = 0.06), biliary (P = 0.290) or vascular complications (P = 0.190), perioperative haemorrhage (P = 0.150), post-operative mortality (P = 0.810) and rejection (P = 0.160). The incidence of SFSS in grafts with a GRWR <0.8 is more than in GRWR ≥0.8; however, the low GRWR does not appear to impact perioperative outcomes or graft survival. © 2018 Royal Australasian College of Surgeons.

  13. The Impact Hazard

    NASA Technical Reports Server (NTRS)

    Morrison, David

    1994-01-01

    The Earth has been subject to hypervelocity impacts from comets and asteroids since its formation, and such impacts have played an important role in the evolution of life on our planet. We now recognize not only the historical role of impacts, but the contemporary hazard posed by such events. In the absence of a complete census of potentially threatening Earth-crossing asteroids or comets (called collectively Near Earth Objects, or NEOs), or even of a comprehensive cur-rent search program to identify NEOs, we can consider the hazard only from a probabilistic perspective. We know the steep power-law relationship between NEO numbers and size, with many more small bodies than large ones. We also know that few objects less than about 50 m in diameter (with kinetic energy near 10 megatons) penetrate the atmosphere and are capable of doing surface damage. But there is a spectrum of possible impact hazards associated with objects from this 10-megaton threshold all the way up to NEOs 5 km or larger in diameter, which are capable of inflicting severe damage on the environment, leading to mass extinction's of species. Detailed analysis has shown that, in general, the larger the object the greater the hazard, even when allowance is made for the infrequency of large impacts. Most of the danger to human life is associated with impacts by objects roughly 2 km or larger (energy greater than 1 million megatons), which can inject sufficient submicrometer dust into the atmosphere to produce a severe short-term global cooling with subsequent loss of crops, leading to starvation. Hazard estimates suggest that the chance of such an event occurring during a human lifetime is about 1:5000, and the global probability of death from such impacts is of the order of 1:20000, values that can be compared with risks associated with other natural hazards such as earthquakes, volcanic eruptions, and severe storms. However, the impact hazard differs from the others in that it can be largely

  14. 14 CFR 417.413 - Hazard areas.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... controls during public access. A launch operator must establish procedural controls that prevent hazardous... that system hazard controls are in place that prevent initiation of a hazardous event. Hazard controls... devices or other restraints on system actuation switches or other controls to eliminate the possibility of...

  15. 14 CFR 417.413 - Hazard areas.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... controls during public access. A launch operator must establish procedural controls that prevent hazardous... that system hazard controls are in place that prevent initiation of a hazardous event. Hazard controls... devices or other restraints on system actuation switches or other controls to eliminate the possibility of...

  16. 14 CFR 417.413 - Hazard areas.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... controls during public access. A launch operator must establish procedural controls that prevent hazardous... that system hazard controls are in place that prevent initiation of a hazardous event. Hazard controls... devices or other restraints on system actuation switches or other controls to eliminate the possibility of...

  17. Natural Hazards, Second Edition

    NASA Astrophysics Data System (ADS)

    Rouhban, Badaoui

    Natural disaster loss is on the rise, and the vulnerability of the human and physical environment to the violent forces of nature is increasing. In many parts of the world, disasters caused by natural hazards such as earthquakes, floods, landslides, drought, wildfires, intense windstorms, tsunami, and volcanic eruptions have caused the loss of human lives, injury, homelessness, and the destruction of economic and social infrastructure. Over the last few years, there has been an increase in the occurrence, severity, and intensity of disasters, culminating with the devastating tsunami of 26 December 2004 in South East Asia.Natural hazards are often unexpected or uncontrollable natural events of varying magnitude. Understanding their mechanisms and assessing their distribution in time and space are necessary for refining risk mitigation measures. This second edition of Natural Hazards, (following a first edition published in 1991 by Cambridge University Press), written by Edward Bryant, associate dean of science at Wollongong University, Australia, grapples with this crucial issue, aspects of hazard prediction, and other issues. The book presents a comprehensive analysis of different categories of hazards of climatic and geological origin.

  18. Property-close source separation of hazardous waste and waste electrical and electronic equipment--a Swedish case study.

    PubMed

    Bernstad, Anna; la Cour Jansen, Jes; Aspegren, Henrik

    2011-03-01

    Through an agreement with EEE producers, Swedish municipalities are responsible for collection of hazardous waste and waste electrical and electronic equipment (WEEE). In most Swedish municipalities, collection of these waste fractions is concentrated to waste recycling centres where households can source-separate and deposit hazardous waste and WEEE free of charge. However, the centres are often located on the outskirts of city centres and cars are needed in order to use the facilities in most cases. A full-scale experiment was performed in a residential area in southern Sweden to evaluate effects of a system for property-close source separation of hazardous waste and WEEE. After the system was introduced, results show a clear reduction in the amount of hazardous waste and WEEE disposed of incorrectly amongst residual waste or dry recyclables. The systems resulted in a source separation ratio of 70 wt% for hazardous waste and 76 wt% in the case of WEEE. Results show that households in the study area were willing to increase source separation of hazardous waste and WEEE when accessibility was improved and that this and similar collection systems can play an important role in building up increasingly sustainable solid waste management systems. Copyright © 2010 Elsevier Ltd. All rights reserved.

  19. Direction based Hazard Routing Protocol (DHRP) for disseminating road hazard information using road side infrastructures in VANETs.

    PubMed

    Berlin, M A; Anand, Sheila

    2014-01-01

    This paper presents Direction based Hazard Routing Protocol (DHRP) for disseminating information about fixed road hazards such as road blocks, tree fall, boulders on road, snow pile up, landslide, road maintenance work and other obstacles to the vehicles approaching the hazardous location. The proposed work focuses on dissemination of hazard messages on highways with sparse traffic. The vehicle coming across the hazard would report the presence of the hazard. It is proposed to use Road Side fixed infrastructure Units for reliable and timely delivery of hazard messages to vehicles. The vehicles can then take appropriate safety action to avoid the hazardous location. The proposed protocol has been implemented and tested using SUMO simulator to generate road traffic and NS 2.33 network simulator to analyze the performance of DHRP. The performance of the proposed protocol was also compared with simple flooding protocol and the results are presented.

  20. Estimating piecewise exponential frailty model with changing prior for baseline hazard function

    NASA Astrophysics Data System (ADS)

    Thamrin, Sri Astuti; Lawi, Armin

    2016-02-01

    Piecewise exponential models provide a very flexible framework for modelling univariate survival data. It can be used to estimate the effects of different covariates which are influenced by the survival data. Although in a strict sense it is a parametric model, a piecewise exponential hazard can approximate any shape of a parametric baseline hazard. In the parametric baseline hazard, the hazard function for each individual may depend on a set of risk factors or explanatory variables. However, it usually does not explain all such variables which are known or measurable, and these variables become interesting to be considered. This unknown and unobservable risk factor of the hazard function is often termed as the individual's heterogeneity or frailty. This paper analyses the effects of unobserved population heterogeneity in patients' survival times. The issue of model choice through variable selection is also considered. A sensitivity analysis is conducted to assess the influence of the prior for each parameter. We used the Markov Chain Monte Carlo method in computing the Bayesian estimator on kidney infection data. The results obtained show that the sex and frailty are substantially associated with survival in this study and the models are relatively quite sensitive to the choice of two different priors.

  1. Designing Effective Natural Hazards Preparedness Communications: Factors that Influence Perceptions and Action

    NASA Astrophysics Data System (ADS)

    Wong-Parodi, G.; Fischhoff, B.

    2012-12-01

    Even though most people believe that natural hazards preparation is important for mitigating damage to their homes and basic survival in the aftermath of a disaster, few actually disaster-proof their homes, create plans, or obtain supplies recommended by agencies such as the Federal Emergency Management Agency. Several observational studies suggest that socio-demographic characteristics such as income and psychological characteristics such as self-efficacy affect whether or not an individual takes action to prepare for a natural hazard. These studies, however, only suggest that these characteristics may play a role. There has been little research that systematically investigates how these characteristics play a role in people's perceptions of recommended preparatory activities and decisions to perform them. Therefore, in Study 1, we explore people's perceptions of natural hazards preparedness measures on four dimensions: time, cost, helpfulness, and sense of preparedness. We further investigate if these responses vary by the socio-demographic and psychological characteristics of self-efficacy, knowledge, and income level. In Study 2, we experimentally test whether people's sense of self-efficacy, as it relates to natural hazards, can be manipulated through exposure to an "easy-and-effective" versus a "hard-and-effective" set of preparation measures. Our findings have implications for the design of natural hazards communication materials for the general public.

  2. Peripheral CD4+ naïve/memory ratio is an independent predictor of survival in non-small cell lung cancer

    PubMed Central

    Yang, Peng; Ma, Junhong; Yang, Xin; Li, Wei

    2017-01-01

    Background To investigate the clinical significance of naïve T cells, memory T cells, CD45RA+CD45RO+ T cells, and naïve/memory ratio in non-small cell lung cancer (NSCLC) patients. Methods Pretreatment peripheral blood samples from 76 NSCLC patients and 28 age- and sex-matched healthy volunteers were collected and tested for immune cells by flow cytometry. We compared the expression of these immune cells between patients and healthy controls and evaluated their predictive roles for survival in NSCLC by cox proportional hazards model. Results Decreased naïve CD4+ T cells, naïve CD8+ T cells, CD4+ naïve/memory ratios and CD4+CD45RA+CD45RO+ T cells, and increased memory CD4+ T cells, were observed in 76 NSCLC patients compared to healthy volunteers. Univariate analysis revealed that elevated CD4+ naïve/memory ratio correlated with prolonged progression-free survival (P=0.013). Multivariate analysis confirmed its predictive role with a hazard ratio of 0.35 (95% confidence interval, 0.19-0.75, P=0.012). Conclusions Peripheral CD4+ naïve/memory ratio can be used as a predictive biomarker in NSCLC patients and used to optimize personalized treatment strategies. PMID:29137371

  3. A stochastic automata network for earthquake simulation and hazard estimation

    NASA Astrophysics Data System (ADS)

    Belubekian, Maya Ernest

    1998-11-01

    This research develops a model for simulation of earthquakes on seismic faults with available earthquake catalog data. The model allows estimation of the seismic hazard at a site of interest and assessment of the potential damage and loss in a region. There are two approaches for studying the earthquakes: mechanistic and stochastic. In the mechanistic approach, seismic processes, such as changes in stress or slip on faults, are studied in detail. In the stochastic approach, earthquake occurrences are simulated as realizations of a certain stochastic process. In this dissertation, a stochastic earthquake occurrence model is developed that uses the results from dislocation theory for the estimation of slip released in earthquakes. The slip accumulation and release laws and the event scheduling mechanism adopted in the model result in a memoryless Poisson process for the small and moderate events and in a time- and space-dependent process for large events. The minimum and maximum of the hazard are estimated by the model when the initial conditions along the faults correspond to a situation right after a largest event and after a long seismic gap, respectively. These estimates are compared with the ones obtained from a Poisson model. The Poisson model overestimates the hazard after the maximum event and underestimates it in the period of a long seismic quiescence. The earthquake occurrence model is formulated as a stochastic automata network. Each fault is divided into cells, or automata, that interact by means of information exchange. The model uses a statistical method called bootstrap for the evaluation of the confidence bounds on its results. The parameters of the model are adjusted to the target magnitude patterns obtained from the catalog. A case study is presented for the city of Palo Alto, where the hazard is controlled by the San Andreas, Hayward and Calaveras faults. The results of the model are used to evaluate the damage and loss distribution in Palo Alto

  4. An international perspective on hazardous waste practices.

    PubMed

    Orloff, Kenneth; Falk, Henry

    2003-08-01

    In developing countries, public health attention is focused on urgent health problems such as infectious diseases, malnutrition, and infant mortality. As a country develops and gains economic resources, more attention is directed to health concerns related to hazardous chemical wastes. Even if a country has little industry of its own that generates hazardous wastes, the importation of hazardous wastes for recycling or disposal can present health hazards. It is difficult to compare the quantities of hazardous wastes produced in different countries because of differences in how hazardous wastes are defined. In most countries, landfilling is the most common means of hazardous waste disposal, although substantial quantities of hazardous wastes are incinerated in some countries. Hazardous wastes that escape into the environment most often impact the public through air and water contamination. An effective strategy for managing hazardous wastes should encourage waste minimization, recycling, and reuse over disposal. Developing countries are especially in need of low-cost technologies for managing hazardous wastes.

  5. Hazardous waste: cleanup and prevention

    USGS Publications Warehouse

    Vandas, Stephen; Cronin, Nancy L.; Farrar, Frank; Serrano, Guillermo Eliezer Ávila; Yajimovich, Oscar Efraín González; Muñoz, Aurora R.; Rivera, María del C.

    1996-01-01

    Our lifestyles are supported by complex Industrial activities that produce many different chemicals and chemical wastes. The Industries that produce our clothing, cars, medicines, paper, food, fuels, steel, plastics, and electric components use and discard thousands of chemicals every year. At home we may use lawn chemicals, solvents, disinfectants, cleaners, and auto products to Improve our quality of life. A chemical that presents a threat or unreasonable risk to people or the environment Is a hazardous material. When a hazardous material can no longer be used, It becomes a hazardous waste. Hazardous wastes come from a variety of sources, from both present and past activities. Impacts to human health and the environment can result from Improper handling and disposal of hazardous waste.

  6. Hydrothermal Liquefaction Treatment Hazard Analysis Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lowry, Peter P.; Wagner, Katie A.

    Hazard analyses were performed to evaluate the modular hydrothermal liquefaction treatment system. The hazard assessment process was performed in 2 stages. An initial assessment utilizing Hazard Identification and Preliminary Hazards Analysis (PHA) techniques identified areas with significant or unique hazards (process safety-related hazards) that fall outside of the normal operating envelope of PNNL and warranted additional analysis. The subsequent assessment was based on a qualitative What-If analysis. The analysis was augmented, as necessary, by additional quantitative analysis for scenarios involving a release of hazardous material or energy with the potential for affecting the public. The following selected hazardous scenarios receivedmore » increased attention: •Scenarios involving a release of hazardous material or energy, controls were identified in the What-If analysis table that prevent the occurrence or mitigate the effects of the release. •Scenarios with significant consequences that could impact personnel outside the immediate operations area, quantitative analyses were performed to determine the potential magnitude of the scenario. The set of “critical controls” were identified for these scenarios (see Section 4) which prevent the occurrence or mitigate the effects of the release of events with significant consequences.« less

  7. Proposed method for hazard mapping of landslide propagation zone

    NASA Astrophysics Data System (ADS)

    Serbulea, Manole-Stelian; Gogu, Radu; Manoli, Daniel-Marcel; Gaitanaru, Dragos Stefan; Priceputu, Adrian; Andronic, Adrian; Anghel, Alexandra; Liviu Bugea, Adrian; Ungureanu, Constantin; Niculescu, Alexandru

    2013-04-01

    Sustainable development of communities situated in areas with landslide potential requires a fully understanding of the mechanisms that govern the triggering of the phenomenon as well as the propagation of the sliding mass, with catastrophic consequences on the nearby inhabitants and environment. Modern analysis methods for areas affected by the movement of the soil bodies are presented in this work, as well as a new procedure to assess the landslide hazard. Classical soil mechanics offer sufficient numeric models to assess the landslide triggering zone, such as Limit Equilibrium Methods (Fellenius, Janbu, Morgenstern-Price, Bishop, Spencer etc.), blocks model or progressive mobilization models, Lagrange-based finite element method etc. The computation methods for assessing the propagation zones are quite recent and have high computational requirements, thus not being sufficiently used in practice to confirm their feasibility. The proposed procedure aims to assess not only the landslide hazard factor, but also the affected areas, by means of simple mathematical operations. The method can easily be employed in GIS software, without requiring engineering training. The result is obtained by computing the first and second derivative of the digital terrain model (slope and curvature maps). Using the curvature maps, it is shown that one can assess the areas most likely to be affected by the propagation of the sliding masses. The procedure is first applied on a simple theoretical model and then used on a representative section of a high exposure area in Romania. The method is described by comparison with Romanian legislation for risk and vulnerability assessment, which specifies that the landslide hazard is to be assessed, using an average hazard factor Km, obtained from various other factors. Following the employed example, it is observed that using the Km factor there is an inconsistent distribution of the polygonal surfaces corresponding to different landslide

  8. Transportation of hazardous materials

    DOT National Transportation Integrated Search

    1986-07-01

    This report discusses transportation of all hazardous materials (commodities, : radioactive materials including spent nuclear fuel, and hazardous wastes) that : travel by truck, rail, water, or air. The Office of Technology Assessment (OTA) : has ide...

  9. Hydrolysis of aluminum dross material to achieve zero hazardous waste.

    PubMed

    David, E; Kopac, J

    2012-03-30

    A simple method with high efficiency for generating high pure hydrogen by hydrolysis in tap water of highly activated aluminum dross is established. Aluminum dross is activated by mechanically milling to particles of about 45 μm. This leads to removal of surface layer of the aluminum particles and creation of a fresh chemically active metal surface. In contact with water the hydrolysis reaction takes place and hydrogen is released. In this process a Zero Waste concept is achieved because the other product of reaction is aluminum oxide hydroxide (AlOOH), which is nature-friendly and can be used to make high quality refractory or calcium aluminate cement. For comparison we also used pure aluminum powder and alkaline tap water solution (NaOH, KOH) at a ratio similar to that of aluminum dross content. The rates of hydrogen generated in hydrolysis reaction of pure aluminum and aluminum dross have been found to be similar. As a result of the experimental setup, a hydrogen generator was designed and assembled. Hydrogen volume generated by hydrolysis reaction was measured. The experimental results obtained reveal that aluminum dross could be economically recycled by hydrolysis process with achieving zero hazardous aluminum dross waste and hydrogen generation. Copyright © 2012 Elsevier B.V. All rights reserved.

  10. 75 FR 67919 - Hazardous Waste Management System; Proposed Exclusion for Identifying and Listing Hazardous Waste

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-11-04

    ...-R05-RCRA-2010-0843; SW-FRL-9221-2] Hazardous Waste Management System; Proposed Exclusion for Identifying and Listing Hazardous Waste AGENCY: Environmental Protection Agency (EPA). ACTION: Proposed rule... hazardous wastes. The Agency has tentatively decided to grant the petition based on an evaluation of waste...

  11. Occupational health hazards in veterinary medicine: Physical, psychological, and chemical hazards

    PubMed Central

    Epp, Tasha; Waldner, Cheryl

    2012-01-01

    This paper reports physical, psychological, and chemical hazards relevant to western Canadian veterinarians as obtained by a self-administered mailed questionnaire. Nine-three percent (750/806) of veterinarians reported some form of injury during the previous 5 years; 17% of respondents (131/791) indicated injuries that resulted in 1 or more days off work. Median stress levels were similar across work environments; overall, 7% (57/813) indicated either no stress or severe stress, while 53% (428/813) indicated moderate stress. Twenty percent (3/15) of food animal practitioners and 37% (114/308) of companion animal practitioners who took X-rays reported accidental exposure. Accidental exposure to gas anesthetic was reported by 69% (394/570) of those in private practice. Exposure to chemicals occurred in all work environments. Veterinarians in western Canada are at risk of minor to severe injury due to both animal and non-animal related causes. PMID:22851776

  12. Occupational health hazards in veterinary medicine: physical, psychological, and chemical hazards.

    PubMed

    Epp, Tasha; Waldner, Cheryl

    2012-02-01

    This paper reports physical, psychological, and chemical hazards relevant to western Canadian veterinarians as obtained by a self-administered mailed questionnaire. Nine-three percent (750/806) of veterinarians reported some form of injury during the previous 5 years; 17% of respondents (131/791) indicated injuries that resulted in 1 or more days off work. Median stress levels were similar across work environments; overall, 7% (57/813) indicated either no stress or severe stress, while 53% (428/813) indicated moderate stress. Twenty percent (3/15) of food animal practitioners and 37% (114/308) of companion animal practitioners who took X-rays reported accidental exposure. Accidental exposure to gas anesthetic was reported by 69% (394/570) of those in private practice. Exposure to chemicals occurred in all work environments. Veterinarians in western Canada are at risk of minor to severe injury due to both animal and non-animal related causes.

  13. 49 CFR 172.205 - Hazardous waste manifest.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 49 Transportation 2 2010-10-01 2010-10-01 false Hazardous waste manifest. 172.205 Section 172.205 Transportation Other Regulations Relating to Transportation PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS REGULATIONS HAZARDOUS MATERIALS TABLE, SPECIAL PROVISIONS, HAZARDOUS MATERIALS...

  14. Image processing for hazard recognition in on-board weather radar

    NASA Technical Reports Server (NTRS)

    Kelly, Wallace E. (Inventor); Rand, Timothy W. (Inventor); Uckun, Serdar (Inventor); Ruokangas, Corinne C. (Inventor)

    2003-01-01

    A method of providing weather radar images to a user includes obtaining radar image data corresponding to a weather radar image to be displayed. The radar image data is image processed to identify a feature of the weather radar image which is potentially indicative of a hazardous weather condition. The weather radar image is displayed to the user along with a notification of the existence of the feature which is potentially indicative of the hazardous weather condition. Notification can take the form of textual information regarding the feature, including feature type and proximity information. Notification can also take the form of visually highlighting the feature, for example by forming a visual border around the feature. Other forms of notification can also be used.

  15. Transportation of Hazardous Evidentiary Material.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Osborn, Douglas.

    2005-06-01

    This document describes the specimen and transportation containers currently available for use with hazardous and infectious materials. A detailed comparison of advantages, disadvantages, and costs of the different technologies is included. Short- and long-term recommendations are also provided.3 DraftDraftDraftExecutive SummaryThe Federal Bureau of Investigation's Hazardous Materials Response Unit currently has hazardous material transport containers for shipping 1-quart paint cans and small amounts of contaminated forensic evidence, but the containers may not be able to maintain their integrity under accident conditions or for some types of hazardous materials. This report provides guidance and recommendations on the availability of packages for themore » safe and secure transport of evidence consisting of or contaminated with hazardous chemicals or infectious materials. Only non-bulk containers were considered because these are appropriate for transport on small aircraft. This report will addresses packaging and transportation concerns for Hazardous Classes 3, 4, 5, 6, 8, and 9 materials. If the evidence is known or suspected of belonging to one of these Hazardous Classes, it must be packaged in accordance with the provisions of 49 CFR Part 173. The anthrax scare of several years ago, and less well publicized incidents involving unknown and uncharacterized substances, has required that suspicious substances be sent to appropriate analytical laboratories for analysis and characterization. Transportation of potentially hazardous or infectious material to an appropriate analytical laboratory requires transport containers that maintain both the biological and chemical integrity of the substance in question. As a rule, only relatively small quantities will be available for analysis. Appropriate transportation packaging is needed that will maintain the integrity of the substance, will not allow biological alteration, will not react chemically with the substance

  16. Hazardous Chemical Fluorometer Development.

    DTIC Science & Technology

    1981-02-01

    RD-0129 997 HAZARDOUS CHEMICAL FLUOROMETER DEYELOPNENT(U) JOHNS HOPKINS UNIV LAUREL RD APPLIED PHYSICS LAB 6 S KEYS FEB Bi JHU/RPL/EED-Bi-6B USCO-D...TEST CHART REr-CRT NO: Cr-n-79-81 Hazardous Chemical Fluorometer Development -- Gary S. Keys q Ft THE JOHNS HOPKINS UNIVERSITYqFt. ill) APPLIED PHYSICS...Connecticut 06340 - 0 I CG-D-79-81/ Ah 7_> Hazardous Chemical Fluorometer Development February 1981 88898 7. ,~rrro z 9. NO-0.C as, 0-a ., AII=q1. Wo

  17. 14 CFR 437.29 - Hazard analysis.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Hazard analysis. 437.29 Section 437.29... Documentation § 437.29 Hazard analysis. (a) An applicant must perform a hazard analysis that complies with § 437.55(a). (b) An applicant must provide to the FAA all the results of each step of the hazard analysis...

  18. 14 CFR 437.29 - Hazard analysis.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 14 Aeronautics and Space 4 2011-01-01 2011-01-01 false Hazard analysis. 437.29 Section 437.29... Documentation § 437.29 Hazard analysis. (a) An applicant must perform a hazard analysis that complies with § 437.55(a). (b) An applicant must provide to the FAA all the results of each step of the hazard analysis...

  19. Long-term multi-hazard assessment for El Misti volcano (Peru)

    NASA Astrophysics Data System (ADS)

    Sandri, Laura; Thouret, Jean-Claude; Constantinescu, Robert; Biass, Sébastien; Tonini, Roberto

    2014-02-01

    We propose a long-term probabilistic multi-hazard assessment for El Misti Volcano, a composite cone located <20 km from Arequipa. The second largest Peruvian city is a rapidly expanding economic centre and is classified by UNESCO as World Heritage. We apply the Bayesian Event Tree code for Volcanic Hazard (BET_VH) to produce probabilistic hazard maps for the predominant volcanic phenomena that may affect c.900,000 people living around the volcano. The methodology accounts for the natural variability displayed by volcanoes in their eruptive behaviour, such as different types/sizes of eruptions and possible vent locations. For this purpose, we treat probabilistically several model runs for some of the main hazardous phenomena (lahars, pyroclastic density currents (PDCs), tephra fall and ballistic ejecta) and data from past eruptions at El Misti (tephra fall, PDCs and lahars) and at other volcanoes (PDCs). The hazard maps, although neglecting possible interactions among phenomena or cascade effects, have been produced with a homogeneous method and refer to a common time window of 1 year. The probability maps reveal that only the north and east suburbs of Arequipa are exposed to all volcanic threats except for ballistic ejecta, which are limited to the uninhabited but touristic summit cone. The probability for pyroclastic density currents reaching recently expanding urban areas and the city along ravines is around 0.05 %/year, similar to the probability obtained for roof-critical tephra loading during the rainy season. Lahars represent by far the most probable threat (around 10 %/year) because at least four radial drainage channels can convey them approximately 20 km away from the volcano across the entire city area in heavy rain episodes, even without eruption. The Río Chili Valley represents the major concern to city safety owing to the probable cascading effect of combined threats: PDCs and rockslides, dammed lake break-outs and subsequent lahars or floods

  20. The California Hazards Institute

    NASA Astrophysics Data System (ADS)

    Rundle, J. B.; Kellogg, L. H.; Turcotte, D. L.

    2006-12-01

    California's abundant resources are linked with its natural hazards. Earthquakes, landslides, wildfires, floods, tsunamis, volcanic eruptions, severe storms, fires, and droughts afflict the state regularly. These events have the potential to become great disasters, like the San Francisco earthquake and fire of 1906, that overwhelm the capacity of society to respond. At such times, the fabric of civic life is frayed, political leadership is tested, economic losses can dwarf available resources, and full recovery can take decades. A patchwork of Federal, state and local programs are in place to address individual hazards, but California lacks effective coordination to forecast, prevent, prepare for, mitigate, respond to, and recover from, the harmful effects of natural disasters. Moreover, we do not know enough about the frequency, size, time, or locations where they may strike, nor about how the natural environment and man-made structures would respond. As California's population grows and becomes more interdependent, even moderate events have the potential to trigger catastrophes. Natural hazards need not become natural disasters if they are addressed proactively and effectively, rather than reactively. The University of California, with 10 campuses distributed across the state, has world-class faculty and students engaged in research and education in all fields of direct relevance to hazards. For that reason, the UC can become a world leader in anticipating and managing natural hazards in order to prevent loss of life and property and degradation of environmental quality. The University of California, Office of the President, has therefore established a new system-wide Multicampus Research Project, the California Hazards Institute (CHI), as a mechanism to research innovative, effective solutions for California. The CHI will build on the rich intellectual capital and expertise of the Golden State to provide the best available science, knowledge and tools for

  1. Ground motion models used in the 2014 U.S. National Seismic Hazard Maps

    USGS Publications Warehouse

    Rezaeian, Sanaz; Petersen, Mark D.; Moschetti, Morgan P.

    2015-01-01

    The National Seismic Hazard Maps (NSHMs) are an important component of seismic design regulations in the United States. This paper compares hazard using the new suite of ground motion models (GMMs) relative to hazard using the suite of GMMs applied in the previous version of the maps. The new source characterization models are used for both cases. A previous paper (Rezaeian et al. 2014) discussed the five NGA-West2 GMMs used for shallow crustal earthquakes in the Western United States (WUS), which are also summarized here. Our focus in this paper is on GMMs for earthquakes in stable continental regions in the Central and Eastern United States (CEUS), as well as subduction interface and deep intraslab earthquakes. We consider building code hazard levels for peak ground acceleration (PGA), 0.2-s, and 1.0-s spectral accelerations (SAs) on uniform firm-rock site conditions. The GMM modifications in the updated version of the maps created changes in hazard within 5% to 20% in WUS; decreases within 5% to 20% in CEUS; changes within 5% to 15% for subduction interface earthquakes; and changes involving decreases of up to 50% and increases of up to 30% for deep intraslab earthquakes for most U.S. sites. These modifications were combined with changes resulting from modifications in the source characterization models to obtain the new hazard maps.

  2. Susceptibility patterns for amoxicillin/clavulanate tests mimicking the licensed formulations and pharmacokinetic relationships: do the MIC obtained with 2:1 ratio testing accurately reflect activity against beta-lactamase-producing strains of Haemophilus influenzae and Moraxella catarrhalis?

    PubMed

    Pottumarthy, Sudha; Sader, Helio S; Fritsche, Thomas R; Jones, Ronald N

    2005-11-01

    Amoxicillin/clavulanate has recently undergone formulation changes (XR and ES-600) that represent 14:1 and 16:1 ratios of amoxicillin/clavulanate. These ratios greatly differ from the 2:1 ratio used in initial formulations and in vitro susceptibility testing. The objective of this study was to determine if the reference method using a 2:1 ratio accurately reflects the susceptibility to the various clinically used amoxicillin/clavulanate formulations and their respective serum concentration ratios. A collection of 330 Haemophilus influenzae strains (300 beta-lactamase-positive and 30 beta-lactamase-negative) and 40 Moraxella catarrhalis strains (30 beta-lactamase-positive and 10 beta-lactamase-negative) were tested by the broth microdilution method against eight amoxicillin/clavulanate combinations (4:1, 5:1, 7:1, 9:1, 14:1, and 16:1 ratios; 0.5 and 2 microg/mL fixed clavulanate concentrations) and the minimum inhibitory concentration (MIC) results were compared with those obtained with the reference 2:1 ratio testing. For the beta-lactamase-negative strains of both genera, there was no demonstrable change in the MIC values obtained for all ratios analyzed (2:1 to 16:1). For the beta-lactamase-positive strains of H. influenzae and M. catarrhalis, at ratios >or=4:1 there was a shift in the central tendency of the MIC scatterplot compared with the results of testing 2:1 ratio. As a result, there was a 2-fold dilution increase in the MIC(50) and MIC(90) values, most evident for H. influenzae and BRO-1-producing M. catarrhalis strains. For beta-lactamase-positive strains of H. influenzae, the shift resulted in a change in the interpretive result for 3 isolates (1.0%) from susceptible using the reference method (2:1 ratio) to resistant (8/4 microg/mL; very major error) at the 16:1 ratio. In addition, the number of isolates with MIC values at or 1 dilution lower than the breakpoint (4/2 microg/mL) increased from 5% at 2:1 ratio to 32-33% for ratios 14:1 and 16:1. Our

  3. Lymph node ratio predicts disease-specific survival in melanoma patients.

    PubMed

    Xing, Yan; Badgwell, Brian D; Ross, Merrick I; Gershenwald, Jeffrey E; Lee, Jeffrey E; Mansfield, Paul F; Lucci, Anthony; Cormier, Janice N

    2009-06-01

    The objectives of this analysis were to compare various measures associated with lymph node (LN) dissection and to identify threshold values associated with disease-specific survival (DSS) outcomes in patients with melanoma. Patients with lymph node-positive melanoma who underwent therapeutic LN dissection of the neck, axilla, and inguinal region were identified from the SEER database (1988-2005). We performed Cox multivariate analyses to determine the impact of the total number of LNs removed, number of negative LNs removed, and LN ratio on DSS. Multivariate cut-point analyses were conducted for each anatomic region to identify the threshold values associated with the largest improvement in DSS. The LN ratio was significantly associated with DSS for all LN regions. The LN ratio thresholds resulting in the greatest difference in 5-year DSS were .07, .13, and .18 for neck, axillary, and inguinal regions, respectively, corresponding to 15, 8, and 6 LNs removed per positive lymph node. After adjustment for other clinicopathologic factors, the hazard ratios (HRs) were .53 (95% confidence interval [CI], .40 to .71) in the neck, .52 (95% CI, .42 to .65) in the axillary, and .47 (95% CI, .36 to .61) in the inguinal regions for patients who met the LN ratio threshold. Among the prognostic factors examined, LN ratio was the best indicator of the extent of LN dissection, regardless of anatomic nodal region. These data provide evidence-based guidelines for defining adequate LN dissections in melanoma patients. (c) 2009 American Cancer Society.

  4. Occupational, social, and relationship hazards and psychological distress among low-income workers: implications of the 'inverse hazard law'.

    PubMed

    Krieger, Nancy; Kaddour, Afamia; Koenen, Karestan; Kosheleva, Anna; Chen, Jarvis T; Waterman, Pamela D; Barbeau, Elizabeth M

    2011-03-01

    Few studies have simultaneously included exposure information on occupational hazards, relationship hazards (eg, intimate partner violence) and social hazards (eg, poverty and racial discrimination), especially among low-income multiracial/ethnic populations. A cross-sectional study (2003-2004) of 1202 workers employed at 14 worksites in the greater Boston area of Massachusetts investigated the independent and joint association of occupational, social and relationship hazards with psychological distress (K6 scale). Among this low-income cohort (45% were below the US poverty line), exposure to occupational, social and relationship hazards, per the 'inverse hazard law,' was high: 82% exposed to at least one occupational hazard, 79% to at least one social hazard, and 32% of men and 34% of women, respectively, stated they had been the perpetrator or target of intimate partner violence (IPV). Fully 15.4% had clinically significant psychological distress scores (K6 score ≥ 13). All three types of hazards, and also poverty, were independently associated with increased risk of psychological distress. In models including all three hazards, however, significant associations with psychological distress occurred among men and women for workplace abuse and high exposure to racial discrimination only; among men, for IPV; and among women, for high exposure to occupational hazards, poverty and smoking. Reckoning with the joint and embodied reality of diverse types of hazards involving how people live and work is necessary for understanding determinants of health status.

  5. Volcanic Hazard Maps; the results and progress made by the IAVCEI Hazard Map working group

    NASA Astrophysics Data System (ADS)

    Calder, Eliza; Lindsay, Jan; Wright, Heather

    2017-04-01

    The IAVCEI Commission on Volcanic Hazards and Risk set up a working group on Hazard Maps in 2014. Since then, the group has led or co-organised three major workshops, and organized two thematic conference sessions. In particular we have initiated a series of workshops, named the "State of the Hazard Map" which we plan to continue (the first was held at COV8 (State of the Hazard Map 1) and second at COV9 (State of the Hazard Map 2) and the third will be held at IAVCEI General Assembly in Portland. The broad aim of these activities is to work towards an IAVCEI-endorsed considerations or guidelines document for volcanic hazard map generation. The workshops have brought together people from around the world working on volcanic hazard maps, and have had four primary objectives: 1) to review (and collect further data on) the diverse variety of methods and rationales currently used to develop maps; 2) to openly discuss approaches and experiences regarding how hazard maps are interpreted and used by different groups; 3) to discuss and prepare the IAVCEI Guidelines document; and lastly, 4) Discuss options for finalizing, publishing and disseminating the Guidelines document (e.g. wiki, report, open-source publication). This presentation will provide an update of the results and outcomes of those initiatives. This includes brief outcomes of the reviews undertaken, a survey that has been constructed in order to gather additional data, the planned structure for the guidelines documents and a summary of the key findings to date. The majority of the participants of these activities so far have come from volcano observatories or geological surveys, as these institutions commonly have primary responsibility for making operational hazard map. It is important however that others in the scientific community that work on quantification of volcanic hazard contribute to these guidelines. We therefore invite interested parties to become involved.

  6. There's Life in Hazard Trees

    Treesearch

    Mary Torsello; Toni McLellan

    The goals of hazard tree management programs are to maximize public safety and maintain a healthy sustainable tree resource. Although hazard tree management frequently targets removal of trees or parts of trees that attract wildlife, it can take into account a diversity of tree values. With just a little extra planning, hazard tree management can be highly beneficial...

  7. Dietary sodium to potassium ratio and the incidence of hypertension and cardiovascular disease: A population-based longitudinal study.

    PubMed

    Mirmiran, Parvin; Bahadoran, Zahra; Nazeri, Pantea; Azizi, Fereidoun

    2018-01-30

    There is an interaction between dietary sodium/potassium intake in the pathogenesis of hypertension (HTN) and cardiovascular disease (CVD). The aim of this study was to investigate the association of dietary sodium to potassium (Na/K) ratio and the risk of HTN and CVD in a general population of Iranian adults. In this prospective cohort study, adults men and women with complete baseline data were selected from among participants of the Tehran Lipid and Glucose Study and were followed up for 6.3 years for incidence of HTN and CVD outcomes. Dietary sodium and potassium were assessed using a valid and reliable 168-item food frequency questionnaire. Cox proportional hazards regression models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for the association between dietary sodium, potassium and their ratio and risk of outcomes. During the study follow-up, 291 (15.1%) and 79 (5.0%) new cases of HTN and CVD were identified, respectively. No significant association was observed between usual intakes of sodium, potassium and dietary Na/K ratio with the incidence of HTN. There was no significant association between dietary intakes of sodium and potassium per se and the risk of CVD, whereas when dietary sodium to potassium ratio was considered as exposure in the fully-adjusted Cox regression model, and participants in the highest compared to lowest tertile had a significantly increased risk of CVD (HR = 2.19, 95% CI = 1.16-4.14). Our findings suggest that high dietary Na/K ratio could contribute to increased risk of CVD events.

  8. NEUTROPHIL/LYMPHOCYTE RATIO AND PLATELET/LYMPHOCYTE RATIO IN PATIENTS WITH NSCLC

    PubMed Central

    Cukic, Vesna

    2016-01-01

    Objective: to compare neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) in patients with NSCLC (Non- Small- Cell Lung Cancer): with and without metastases at the time of diagnosis to find out if there is the importance of these cell ratios in the assessment of severity NSCLC. Material and Methods: this is the retrospective analysis of NRL and PRL in patients with NSCLC at the time of the diagnosis of disease before any anti tumor treatment (chemotherapy, radiotherapy, surgery). 57 of patients with NSCLC treated in the first three months of 2016. year were chosen at random regardless of sex and age. We examined full blood count cells (FBC), calculated NLR and PLR in every patient and compared obtained values in patients with and patients without metastases. Results: In 57 patients with NSCLC there were 15 males with metastases, 28 without metastases, and 8 females with metastases, 6 without metastases. Since there was no regularity in the distribution of obtained values of NLR and PLR we made the Mann-Whitney U test. Mean values are presented with a median and interquartile percentiles. There was no significant difference in NLR between patients without and with metastases (p = 0.614; p = NS) as well as in PLR (p=0,068; p=NS). Conclusion: There must be a link between the immune status of the organism and lung cancer development. Immune cells have become of interest in recent years and much work has been done to study their role in the genesis of cancer but it did not give satisfactory results. Further clinical studies on large number of patients and further laboratory examination of the role of immune cells in cancer development and suppression are required. PMID:27999489

  9. Space Debris Hazard Evaluation

    NASA Technical Reports Server (NTRS)

    Davison, Elmer H.; Winslow, Paul C., Jr.

    1961-01-01

    The hazard to space vehicles from natural space debris has been explored. A survey of the available information pertinent to this problem is presented. The hope is that this presentation gives a coherent picture of the knowledge to date in terms of the topic covered. The conclusion reached is that a definite hazard exists but that it can only be poorly assessed on the basis of present information. The need for direct measurement of this hazard is obvious, and some of the problems involved in making these direct measurements have been explored.

  10. Integrated approach for coastal hazards and risks in Sri Lanka

    NASA Astrophysics Data System (ADS)

    Garcin, M.; Desprats, J. F.; Fontaine, M.; Pedreros, R.; Attanayake, N.; Fernando, S.; Siriwardana, C. H. E. R.; de Silva, U.; Poisson, B.

    2008-06-01

    The devastating impact of the tsunami of 26 December 2004 on the shores of the Indian Ocean recalled the importance of knowledge and the taking into account of coastal hazards. Sri Lanka was one of the countries most affected by this tsunami (e.g. 30 000 dead, 1 million people homeless and 70% of the fishing fleet destroyed). Following this tsunami, as part of the French post-tsunami aid, a project to establish a Geographical Information System (GIS) on coastal hazards and risks was funded. This project aims to define, at a pilot site, a methodology for multiple coastal hazards assessment that might be useful for the post-tsunami reconstruction and for development planning. This methodology could be applied to the whole coastline of Sri Lanka. The multi-hazard approach deals with very different coastal processes in terms of dynamics as well as in terms of return period. The first elements of this study are presented here. We used a set of tools integrating a GIS, numerical simulations and risk scenario modelling. While this action occurred in response to the crisis caused by the tsunami, it was decided to integrate other coastal hazards into the study. Although less dramatic than the tsunami these remain responsible for loss of life and damage. Furthermore, the establishment of such a system could not ignore the longer-term effects of climate change on coastal hazards in Sri Lanka. This GIS integrates the physical and demographic data available in Sri Lanka that is useful for assessing the coastal hazards and risks. In addition, these data have been used in numerical modelling of the waves generated during periods of monsoon as well as for the December 2004 tsunami. Risk scenarios have also been assessed for test areas and validated by field data acquired during the project. The results obtained from the models can be further integrated into the GIS and contribute to its enrichment and to help in better assessment and mitigation of these risks. The coastal-hazards

  11. Integrating volcanic hazard data in a systematic approach to develop volcanic hazard maps in the Lesser Antilles

    NASA Astrophysics Data System (ADS)

    Lindsay, Jan M.; Robertson, Richard E. A.

    2018-04-01

    We report on the process of generating the first suite of integrated volcanic hazard zonation maps for the islands of Dominica, Grenada (including Kick 'em Jenny and Ronde/Caille), Nevis, Saba, St. Eustatius, St. Kitts, Saint Lucia and St Vincent in the Lesser Antilles. We developed a systematic approach that accommodated the range in prior knowledge of the volcanoes in the region. A first-order hazard assessment for each island was used to develop one or more scenario(s) of likely future activity, for which scenario-based hazard maps were generated. For the most-likely scenario on each island we also produced a poster-sized integrated volcanic hazard zonation map, which combined the individual hazardous phenomena depicted in the scenario-based hazard maps into integrated hazard zones. We document the philosophy behind the generation of this suite of maps, and the method by which hazard information was combined to create integrated hazard zonation maps, and illustrate our approach through a case study of St. Vincent. We also outline some of the challenges we faced using this approach, and the lessons we have learned by observing how stakeholders have interacted with the maps over the past 10 years. Based on our experience, we recommend that future map makers involve stakeholders in the entire map generation process, especially when making design choices such as type of base map, use of colour and gradational boundaries, and indeed what to depict on the map. We also recommend careful consideration of how to evaluate and depict offshore hazard of island volcanoes, and recommend computer-assisted modelling of all phenomena to generate more realistic hazard footprints. Finally, although our systematic approach to integrating individual hazard data into zones generally worked well, we suggest that a better approach might be to treat the integration of hazards on a case-by-case basis to ensure the final product meets map users' needs. We hope that the documentation of

  12. Successive ratio subtraction as a novel manipulation of ratio spectra for quantitative determination of a mixture of furosemide, spironolactone and canrenone

    NASA Astrophysics Data System (ADS)

    Emam, Aml A.; Abdelaleem, Eglal A.; Naguib, Ibrahim A.; Abdallah, Fatma F.; Ali, Nouruddin W.

    2018-03-01

    Furosemide and spironolactone are commonly prescribed antihypertensive drugs. Canrenone is the main degradation product and main metabolite of spironolactone. Ratio subtraction and extended ratio subtraction spectrophotometric methods were previously applied for quantitation of only binary mixtures. An extension of the above mentioned methods; successive ratio subtraction, is introduced in the presented work for quantitative determination of ternary mixtures exemplified by furosemide, spironolactone and canrenone. Manipulating the ratio spectra of the ternary mixture allowed their determination at 273.6 nm, 285 nm and 240 nm and in the concentration ranges of (2-16 μg mL- 1), (4-32 μg mL- 1) and (1-18 μg mL- 1) for furosemide, spironolactone and canrenone, respectively. Method specificity was ensured by the application to laboratory prepared mixtures. The introduced method was ensured to be accurate and precise. Validation of the developed method was done with respect to ICH guidelines and its validity was further ensured by the application to the pharmaceutical formulation. Statistical comparison between the obtained results and those obtained from the reported HPLC method was achieved concerning student's t-test and F ratio test where no significant difference was observed.

  13. Seismic hazard assessment of Syria using seismicity, DEM, slope, active tectonic and GIS

    NASA Astrophysics Data System (ADS)

    Ahmad, Raed; Adris, Ahmad; Singh, Ramesh

    2016-07-01

    In the present work, we discuss the use of an integrated remote sensing and Geographical Information System (GIS) techniques for evaluation of seismic hazard areas in Syria. The present study is the first time effort to create seismic hazard map with the help of GIS. In the proposed approach, we have used Aster satellite data, digital elevation data (30 m resolution), earthquake data, and active tectonic maps. Many important factors for evaluation of seismic hazard were identified and corresponding thematic data layers (past earthquake epicenters, active faults, digital elevation model, and slope) were generated. A numerical rating scheme has been developed for spatial data analysis using GIS to identify ranking of parameters to be included in the evaluation of seismic hazard. The resulting earthquake potential map delineates the area into different relative susceptibility classes: high, moderate, low and very low. The potential earthquake map was validated by correlating the obtained different classes with the local probability that produced using conventional analysis of observed earthquakes. Using earthquake data of Syria and the peak ground acceleration (PGA) data is introduced to the model to develop final seismic hazard map based on Gutenberg-Richter (a and b values) parameters and using the concepts of local probability and recurrence time. The application of the proposed technique in Syrian region indicates that this method provides good estimate of seismic hazard map compared to those developed from traditional techniques (Deterministic (DSHA) and probabilistic seismic hazard (PSHA). For the first time we have used numerous parameters using remote sensing and GIS in preparation of seismic hazard map which is found to be very realistic.

  14. The Impact Hazard in the Context of Other Natural Hazards and Predictive Science

    NASA Astrophysics Data System (ADS)

    Chapman, C. R.

    1998-09-01

    The hazard due to impact of asteroids and comets has been recognized as analogous, in some ways, to other infrequent but consequential natural hazards (e.g. floods and earthquakes). Yet, until recently, astronomers and space agencies have felt no need to do what their colleagues and analogous agencies must do in order the assess, quantify, and communicate predictions to those with a practical interest in the predictions (e.g. public officials who must assess the threats, prepare for mitigation, etc.). Recent heightened public interest in the impact hazard, combined with increasing numbers of "near misses" (certain to increase as Spaceguard is implemented) requires that astronomers accept the responsibility to place their predictions and assessments in terms that may be appropriately considered. I will report on preliminary results of a multi-year GSA/NCAR study of "Prediction in the Earth Sciences: Use and Misuse in Policy Making" in which I have represented the impact hazard, while others have treated earthquakes, floods, weather, global climate change, nuclear waste disposal, acid rain, etc. The impact hazard presents an end-member example of a natural hazard, helping those dealing with more prosaic issues to learn from an extreme. On the other hand, I bring to the astronomical community some lessons long adopted in other cases: the need to understand the policy purposes of impact predictions, the need to assess potential societal impacts, the requirements to very carefully assess prediction uncertainties, considerations of potential public uses of the predictions, awareness of ethical considerations (e.g. conflicts of interest) that affect predictions and acceptance of predictions, awareness of appropriate means for publicly communicating predictions, and considerations of the international context (especially for a hazard that knows no national boundaries).

  15. Special Issue "Natural Hazards' Impact on Urban Areas and Infrastructure" in Natural Hazards

    NASA Astrophysics Data System (ADS)

    Bostenaru Dan, M.

    2009-04-01

    In 2006 and 2007, at the 3rd and 4th General Assembly of the European Geosciences Union respectivelly, the session on "Natural Hazards' Impact on Urban Areas and Infrastructure" was convened by Maria Bostenaru Dan, then at the Istituto Universitario di Studi Superiori di Pavia, ROSE School, Italy, who conducts research on earthquake management and Heidi Kreibich from the GFZ Potsdam, Germany, who conducts research on flood hazards, in 2007 being co-convened also by Agostino Goretti from the Civil Protection in Rome, Italy. The session initially started from an idea of Friedemann Wenzel from the Universität Karlsruhe (TH), Germany, the former speaker of the SFB 461 "Strong earthquakes", the university where also Maria Bostenaru graduated and worked and which runs together with the GFZ Potsdam the CEDIM, the Center for Disaster Management and Risk Reduction Technology. Selected papers from these two sessions as well as invited papers from other specialists were gathered for a special issue to be published in the journal "Natural Hazards" under the guest editorship of Heidi Kreibich and Maria Bostenaru Dan. Unlike the former special issue, this one contains a well balanced mixture of many hazards: climate change, floods, mountain hazards like avalanches, volcanoes, earthquakes. Aim of the issue was to enlarge the co-operation prospects between geosciences and other professions in field of natural hazards. Earthquake engineering and engineering seismology are seen more frequently co-operating, but in field of natural hazards there is a need to co-operate with urban planners, and, looking to the future, also in the field of integrated conservation, which implies co-operation between architecture and urban planning for the preservation of our environment. Integrated conservation is stipulated since the 1970s, which are the years when the participatism, and so the involvment of social sciences started.

  16. Understanding risk and resilience to natural hazards

    USGS Publications Warehouse

    Wood, Nathan

    2011-01-01

    Natural hazards threaten the safety and economic wellbeing of communities. These hazards include sudden-onset hazards, such as earthquakes, and slowly emerging, chronic hazards, such as those associated with climate change. To help public officials, emergency and other managers, the business community, and at-risk individuals reduce the risks posed by such hazards, the USGS Western Geographic Science Center is developing new ways to assess and communicate societal risk and resilience to catastrophic and chronic natural hazards.

  17. Federal Agency Hazardous Waste Compliance Docket

    EPA Pesticide Factsheets

    The Federal Agency Hazardous Waste Compliance Docket contains information reported to EPA by federal facilities that manage hazardous waste or from which hazardous substances, pollutants, or contaminants have been - or may be - released.

  18. An Introduction to Hazardous Material Management.

    ERIC Educational Resources Information Center

    Reinhardt, Peter A.; And Others

    1987-01-01

    Colleges must have a system to safely control the ordering, delivery, transport, storage, and use of hazardous material. Information on hazardous material management is excerpted from "Managing Hazardous Waste at Educational Institutions. (MLW)

  19. Hazardous Waste Manifest System

    EPA Pesticide Factsheets

    EPA’s hazardous waste manifest system is designed to track hazardous waste from the time it leaves the generator facility where it was produced, until it reaches the off-site waste management facility that will store, treat, or dispose of the waste.

  20. Multidisciplinary Geo-scientific Hazard Analyses: Istanbul Microzonation Projects

    NASA Astrophysics Data System (ADS)

    Kara, Sema; Baş, Mahmut; Kılıç, Osman; Tarih, Ahmet; Yahya Menteşe, Emin; Duran, Kemal

    2017-04-01

    Istanbul (Turkey) is located on the west edge of North Anatolia Fault and hence is an earthquake prone city with a population that exceeds 15 million people. In addition, the city is still growing as center of commerce, tourism and culture that increases the exposure more and more. During the last decade, although Istanbul grew faster than ever in its history, precautions against a possible earthquake have also increased steadily. The two big earthquakes (in Kocaeli and Duzce Provinces) occurred in 1999 alongside Istanbul and these events became the trigger events that accelerated the disaster risk reduction activities in Istanbul. Following a loss estimation study carried out by Japanese International Cooperation Agency (JICA) in 2001 and Istanbul Earthquake Master Plan prepared by four major universities' researchers in 2003; it was evaluated that understanding and analyzing the geological structure in Istanbul was the main concern. Thereafter Istanbul Metropolitan Municipality's Directorate of Earthquake and Ground Research (DEGRE) carried out two major geo-scientific studies called "microzonation studies" covering 650 km2 of Istanbul's urbanized areas between 2006 and 2009. The studies were called "microzonation" because the analysis resolution was as dense as 250m grids and included various assessments on hazards such as ground shaking, liquefaction, karstification, landslide, flooding, and surface faulting. After the evaluation of geological, geotechnical and geophysical measurements; Earthquake and Tsunami Hazard Maps for all Istanbul, slope, engineering geology, ground water level, faulting, ground shaking, inundation, shear wave velocity and soil classification maps for the project areas were obtained. In the end "Land Suitability Maps" are derived from the combination of inputs using multi-hazard approach. As a result, microzonation is tool for risk oriented urban planning; consisting of interdisciplinary multi-hazard risk analyses. The outputs of

  1. Increased Rate of Hospitalization for Diabetes and Residential Proximity of Hazardous Waste Sites

    PubMed Central

    Kouznetsova, Maria; Huang, Xiaoyu; Ma, Jing; Lessner, Lawrence; Carpenter, David O.

    2007-01-01

    Background Epidemiologic studies suggest that there may be an association between environmental exposure to persistent organic pollutants (POPs) and diabetes. Objective The aim of this study was to test the hypothesis that residential proximity to POP-contaminated waste sites result in increased rates of hospitalization for diabetes. Methods We determined the number of hospitalized patients 25–74 years of age diagnosed with diabetes in New York State exclusive of New York City for the years 1993–2000. Descriptive statistics and negative binomial regression were used to compare diabetes hospitalization rates in individuals who resided in ZIP codes containing or abutting hazardous waste sites containing POPs (“POP” sites); ZIP codes containing hazardous waste sites but with wastes other than POPs (“other” sites); and ZIP codes without any identified hazardous waste sites (“clean” sites). Results Compared with the hospitalization rates for diabetes in clean sites, the rate ratios for diabetes discharges for people residing in POP sites and “other” sites, after adjustment for potential confounders were 1.23 [95% confidence interval (CI), 1.15–1.32] and 1.25 (95% CI, 1.16–1.34), respectively. In a subset of POP sites along the Hudson River, where there is higher income, less smoking, better diet, and more exercise, the rate ratio was 1.36 (95% CI, 1.26–1.47) compared to clean sites. Conclusions After controlling for major confounders, we found a statistically significant increase in the rate of hospitalization for diabetes among the population residing in the ZIP codes containing toxic waste sites. PMID:17366823

  2. Rail-highway crossing hazard prediction : research results

    DOT National Transportation Integrated Search

    1979-12-01

    This document presents techniques for constructing and evaluating railroad grade : crossing hazard indexes. Hazard indexes are objective formulas for comparing or ranking : crossings according to relative hazard or for calculating absolute hazard (co...

  3. TREATMENT OF METAL-LADEN HAZARDOUS WASTES WITH ADVANCED CLEAN COAL TECHNOLOGY BY-PRODUCTS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    James T. Cobb, Jr.

    2003-09-12

    Metal-laden wastes can be stabilized and solidified using advanced clean coal technology by-products (CCTBs)--fluid bed combustor ash and spray drier solids. These utility-generated treatment chemicals are available for purchase through brokers, and commercial applications of this process are being practiced by treaters of metal-laden hazardous waste. A complex of regulations governs this industry, and sensitivities to this complex has discouraged public documentation of treatment of metal-laden hazardous wastes with CCTBs. This report provides a comprehensive public documentation of laboratory studies that show the efficacy of the stabilization and solidification of metal-laden hazardous wastes--such as lead-contaminated soils and sandblast residues--through treatmentmore » with CCTBs. It then describes the extensive efforts that were made to obtain the permits allowing a commercial hazardous waste treater to utilize CCTBs as treatment chemicals and to install the equipment required to do so. It concludes with the effect of this lengthy process on the ability of the treatment company to realize the practical, physical outcome of this effort, leading to premature termination of the project.« less

  4. Hazard Detection Software for Lunar Landing

    NASA Technical Reports Server (NTRS)

    Huertas, Andres; Johnson, Andrew E.; Werner, Robert A.; Montgomery, James F.

    2011-01-01

    The Autonomous Landing and Hazard Avoidance Technology (ALHAT) Project is developing a system for safe and precise manned lunar landing that involves novel sensors, but also specific algorithms. ALHAT has selected imaging LIDAR (light detection and ranging) as the sensing modality for onboard hazard detection because imaging LIDARs can rapidly generate direct measurements of the lunar surface elevation from high altitude. Then, starting with the LIDAR-based Hazard Detection and Avoidance (HDA) algorithm developed for Mars Landing, JPL has developed a mature set of HDA software for the manned lunar landing problem. Landing hazards exist everywhere on the Moon, and many of the more desirable landing sites are near the most hazardous terrain, so HDA is needed to autonomously and safely land payloads over much of the lunar surface. The HDA requirements used in the ALHAT project are to detect hazards that are 0.3 m tall or higher and slopes that are 5 or greater. Steep slopes, rocks, cliffs, and gullies are all hazards for landing and, by computing the local slope and roughness in an elevation map, all of these hazards can be detected. The algorithm in this innovation is used to measure slope and roughness hazards. In addition to detecting these hazards, the HDA capability also is able to find a safe landing site free of these hazards for a lunar lander with diameter .15 m over most of the lunar surface. This software includes an implementation of the HDA algorithm, software for generating simulated lunar terrain maps for testing, hazard detection performance analysis tools, and associated documentation. The HDA software has been deployed to Langley Research Center and integrated into the POST II Monte Carlo simulation environment. The high-fidelity Monte Carlo simulations determine the required ground spacing between LIDAR samples (ground sample distances) and the noise on the LIDAR range measurement. This simulation has also been used to determine the effect of

  5. Prognostic impact of the pretreatment aspartate transaminase/alanine transaminase ratio in patients treated with first-line systemic tyrosine kinase inhibitor therapy for metastatic renal cell carcinoma.

    PubMed

    Kang, Minyong; Yu, Jiwoong; Sung, Hyun Hwan; Jeon, Hwang Gyun; Jeong, Byong Chang; Park, Se Hoon; Jeon, Seong Soo; Lee, Hyun Moo; Choi, Han Yong; Seo, Seong Il

    2018-05-13

    To examine the prognostic role of the pretreatment aspartate transaminase/alanine transaminase or De Ritis ratio in patients with metastatic renal cell carcinoma receiving first-line systemic tyrosine kinase inhibitor therapy. We retrospectively searched the medical records of 579 patients with metastatic renal cell carcinoma who visited Samsung Medical Center, Seoul, Korea, from January 2001 through August 2016. After excluding 210 patients, we analyzed 360 patients who received first-line tyrosine kinase inhibitor therapy. Cancer-specific survival and overall survival were defined as the primary and secondary end-points, respectively. A multivariate Cox proportional hazards regression model was used to identify independent prognosticators of survival outcomes. The overall population was divided into two groups according to the pretreatment De Ritis ratio as an optimal cut-off value of 1.2, which was determined by a time-dependent receiver operating characteristic curve analysis. Patients with a higher pretreatment De Ritis ratio (≥1.2) had worse cancer-specific survival and overall survival outcomes, compared with those with a lower De Ritis ratio (<1.2). Notably, a higher De Ritis ratio (≥1.2) was found to be an independent predictor of both cancer-specific survival (hazard ratio 1.61, 95% confidence interval 1.13-2.30) and overall survival outcomes (hazard ratio 1.69, 95% confidence interval 1.19-2.39), along with male sex, multiple metastasis (≥2), non-clear cell histology, advanced pT stage (≥3), previous metastasectomy and the Memorial Sloan Kettering Cancer Center risk classification. Our findings show that the pretreatment De Ritis ratio can provide valuable information about the survival outcomes of metastatic renal cell carcinoma patients receiving first-line tyrosine kinase inhibitor therapy. © 2018 The Japanese Urological Association.

  6. Hydrothermal Liquefaction Treatment Preliminary Hazard Analysis Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lowry, Peter P.; Wagner, Katie A.

    A preliminary hazard assessment was completed during February 2015 to evaluate the conceptual design of the modular hydrothermal liquefaction treatment system. The hazard assessment was performed in 2 stages. An initial assessment utilizing Hazard Identification and Preliminary Hazards Analysis (PHA) techniques identified areas with significant or unique hazards (process safety-related hazards) that fall outside of the normal operating envelope of PNNL and warranted additional analysis. The subsequent assessment was based on a qualitative What-If analysis. This analysis was augmented, as necessary, by additional quantitative analysis for scenarios involving a release of hazardous material or energy with the potential for affectingmore » the public.« less

  7. Los Angeles County Department of Public Health's Health Hazard Assessment: putting the "health" into hazard assessment.

    PubMed

    Dean, Brandon; Bagwell, Dee Ann; Dora, Vinita; Khan, Sinan; Plough, Alonzo

    2013-01-01

    A ll communities, explicitly or implicitly, assess and prepare for the natural and manmade hazards that they know could impact their community. The commonality of hazard-based threats in most all communities does not usually result in standard or evidence-based preparedness practice and outcomes across those communities. Without specific efforts to build a shared perspective and prioritization, "all-hazards" preparedness can result in a random hodgepodge of priorities and preparedness strategies, resulting in diminished emergency response capabilities. Traditional risk assessments, with a focus on physical infrastructure, do not present the potential health and medical impacts of specific hazards and threats. With the implementation of Centers for Disease Control and Prevention's capability-based planning, there is broad recognition that a health-focused hazard assessment process--that engages the "Whole of Community"--is needed. Los Angeles County's Health Hazard Assessment and Prioritization tool provides a practical and innovative approach to enhance existing planning capacities. Successful utilization of this tool can provide a way for local and state health agencies and officials to more effectively identify the health consequences related to hazard-specific threats and risk, determine priorities, and develop improved and better coordinated agency planning, including community engagement in prioritization.

  8. Applying the Land Use Portfolio Model with Hazus to analyse risk from natural hazard events

    USGS Publications Warehouse

    Dinitz, Laura B.; Taketa, Richard A.

    2013-01-01

    This paper describes and demonstrates the integration of two geospatial decision-support systems for natural-hazard risk assessment and management. Hazus is a risk-assessment tool developed by the Federal Emergency Management Agency to identify risks and estimate the severity of risk from natural hazards. The Land Use Portfolio Model (LUPM) is a risk-management tool developed by the U.S. Geological Survey to evaluate plans or actions intended to reduce risk from natural hazards. We analysed three mitigation policies for one earthquake scenario in the San Francisco Bay area to demonstrate the added value of using Hazus and the LUPM together. The demonstration showed that Hazus loss estimates can be input to the LUPM to obtain estimates of losses avoided through mitigation, rates of return on mitigation investment, and measures of uncertainty. Together, they offer a more comprehensive approach to help with decisions for reducing risk from natural hazards.

  9. 24 CFR 201.28 - Flood and hazard insurance, and Coastal Barriers properties.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... Coastal Barriers properties. 201.28 Section 201.28 Housing and Urban Development Regulations Relating to... Disbursement Requirements § 201.28 Flood and hazard insurance, and Coastal Barriers properties. (a) Flood... obtained by the borrower in compliance with section 102 of the Flood Disaster Protection Act of 1973 (42 U...

  10. 24 CFR 201.28 - Flood and hazard insurance, and Coastal Barriers properties.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... Coastal Barriers properties. 201.28 Section 201.28 Housing and Urban Development Regulations Relating to... Disbursement Requirements § 201.28 Flood and hazard insurance, and Coastal Barriers properties. (a) Flood... obtained by the borrower in compliance with section 102 of the Flood Disaster Protection Act of 1973 (42 U...

  11. 24 CFR 201.28 - Flood and hazard insurance, and Coastal Barriers properties.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... Coastal Barriers properties. 201.28 Section 201.28 Housing and Urban Development Regulations Relating to... Disbursement Requirements § 201.28 Flood and hazard insurance, and Coastal Barriers properties. (a) Flood... obtained by the borrower in compliance with section 102 of the Flood Disaster Protection Act of 1973 (42 U...

  12. 24 CFR 201.28 - Flood and hazard insurance, and Coastal Barriers properties.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... Coastal Barriers properties. 201.28 Section 201.28 Housing and Urban Development Regulations Relating to... Disbursement Requirements § 201.28 Flood and hazard insurance, and Coastal Barriers properties. (a) Flood... obtained by the borrower in compliance with section 102 of the Flood Disaster Protection Act of 1973 (42 U...

  13. 24 CFR 201.28 - Flood and hazard insurance, and Coastal Barriers properties.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... Coastal Barriers properties. 201.28 Section 201.28 Housing and Urban Development Regulations Relating to... Disbursement Requirements § 201.28 Flood and hazard insurance, and Coastal Barriers properties. (a) Flood... obtained by the borrower in compliance with section 102 of the Flood Disaster Protection Act of 1973 (42 U...

  14. 12 CFR 614.4940 - Required use of standard flood hazard determination form.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 6 2011-01-01 2011-01-01 false Required use of standard flood hazard determination form. 614.4940 Section 614.4940 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM... used in a printed, computerized, or electronic manner. A System institution may obtain the standard...

  15. 12 CFR 339.6 - Required use of standard flood hazard determination form.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 12 Banks and Banking 4 2011-01-01 2011-01-01 false Required use of standard flood hazard determination form. 339.6 Section 339.6 Banks and Banking FEDERAL DEPOSIT INSURANCE CORPORATION REGULATIONS AND... a printed, computerized, or electronic manner. A non-member bank may obtain the standard flood...

  16. An apparatus and procedure for evaluating the toxic hazards of smoldering seating and bedding materials

    NASA Technical Reports Server (NTRS)

    Hilado, C. J.; Brandt, D. L.; Brauer, D. P.

    1978-01-01

    An apparatus and procedure are described for evaluating the toxicity of the gases evolved from the smoldering combustion of seating and bedding materials. The method combines initiation of smoldering combustion in fabric/cushion combinations by a lighted cigarette and exposure of laboratory animals to the gases evolved. The ratio of the surface available for smoldering to the compartment volume in this apparatus is approximately five times the ratio expected in a California living room, and 100 times the ratio expected in a wide-body aircraft passenger cabin. Based on fabric/cushion combinations tested, the toxicity of gases from smoldering combustion does not appear to be a significant hazard in aircraft passenger cabins, but seems to be a basis for careful selection of materials for residential environments.

  17. 75 FR 58346 - Hazardous Waste Management System; Identification and Listing of Hazardous Waste

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-24

    ... Chemical Company-Texas Operations (Eastman) to exclude (or delist) certain solid wastes generated by its Longview, Texas, facility from the lists of hazardous wastes. EPA used the Delisting Risk Assessment... Waste Management System; Identification and Listing of Hazardous Waste AGENCY: Environmental Protection...

  18. Use of biological assay systems to assess the relative carcinogenic hazards of disinfection by-products.

    PubMed Central

    Bull, R J; Robinson, M; Meier, J R; Stober, J

    1982-01-01

    Other workers have clearly shown that most, if not all, drinking water in the U.S. contains chemicals that possess mutagenic and/or carcinogenic activity by using bacterial and in vitro methods. In the present work, increased numbers of tumors were observed with samples of organic material isolated from 5 U.S. cities administered as tumor initiators in mouse skin initiation/promotion studies. Only in one case was the result significantly different from control. In studies designed to test whether disinfection practice contributes significantly to the tumor initiating activity found in drinking water mixed results have been obtained. In one experiment, water disinfected by chlorination, ozonation or combined chlorine resulted in a significantly greater number of papillomas when compared to nondisinfected water. In two subsequent experiments, where water was obtained from the Ohio River at different times of the year, no evidence of increased initiating activity was observed with any disinfectant. Analysis of water obtained at the comparable times of the year for total organic halogen, and trihalomethane formation revealed a substantial variation in the formation of these products. Considering the problems such variability poses for estimating risks associated with disinfection by-products, a model system which makes use of commercially obtained humic acid as a substrate for chlorination was investigated using the Ames test. Humic and fulvic acids obtained from two surface waters as well as the commercially obtained humic acid were without activity in TA 1535, TA 1537, TA 1538, TA 98 or TA 100 strains of S. typhimurium. Following treatment with a 0.8 molar ratio of chlorine (based on carbon) significant mutagenic activity was observed with all humic and fulvic acid samples. Comparisons of the specific mutagenic activity of the chlorinated products suggests that the commercial material might provide a useful model for studying health hazards associated with

  19. Coastal pollution hazards in southern California observed by SAR imagery: stormwater plumes, wastewater plumes, and natural hydrocarbon seeps

    NASA Technical Reports Server (NTRS)

    Digiacomo, Paul M.; Washburn, Libe; Holt, Benjamin; Jones, Burton H.

    2004-01-01

    Stormwater runoff plumes, municipal wastewater plumes, and natural hydrocarbon seeps are important pollution hazards for the heavily populated Southern California Bight (SCB). Due to their small size, dynamic and episodic nature, these hazards are difficult to sample adequately using traditional in situ oceanographic methods. Complex coastal circulation and persistent cloud cover can further complicate detection and monitoring of these hazards. We use imagery from space-borne synthetic aperture radar (SAR), complemented by field measurements, to examine these hazards in the SCB. The hazards are detectable in SAR imagery because they deposit surfactants on the sea surface, smoothing capillary and small gravity waves to produce areas of reduced backscatter compared with the surrounding ocean. We suggest that high-resolution SAR, which obtains useful data regardless of darkness or cloud cover, could be an important observational tool for assessment and monitoring of coastal marine pollution hazards in the SCB and other urbanized coastal regions.

  20. Using hazard maps to identify and eliminate workplace hazards: a union-led health and safety training program.

    PubMed

    Anderson, Joe; Collins, Michele; Devlin, John; Renner, Paul

    2012-01-01

    The Institute for Sustainable Work and Environment and the Utility Workers Union of America worked with a professional evaluator to design, implement, and evaluate the results of a union-led system of safety-based hazard identification program that trained workers to use hazard maps to identify workplace hazards and target them for elimination. The evaluation documented program implementation and impact using data collected from both qualitative interviews and an on-line survey from worker trainers, plant managers, and health and safety staff. Managers and workers reported that not only were many dangerous hazards eliminated as a result of hazard mapping, some of which were long-standing, difficult-to-resolve issues, but the evaluation also documented improved communication between union members and management that both workers and managers agreed resulted in better, more sustainable hazard elimination.

  1. Risk analysis based on hazards interactions

    NASA Astrophysics Data System (ADS)

    Rossi, Lauro; Rudari, Roberto; Trasforini, Eva; De Angeli, Silvia; Becker, Joost

    2017-04-01

    Despite an increasing need for open, transparent, and credible multi-hazard risk assessment methods, models, and tools, the availability of comprehensive risk information needed to inform disaster risk reduction is limited, and the level of interaction across hazards is not systematically analysed. Risk assessment methodologies for different hazards often produce risk metrics that are not comparable. Hazard interactions (consecutive occurrence two or more different events) are generally neglected, resulting in strongly underestimated risk assessment in the most exposed areas. This study presents cases of interaction between different hazards, showing how subsidence can affect coastal and river flood risk (Jakarta and Bandung, Indonesia) or how flood risk is modified after a seismic event (Italy). The analysis of well documented real study cases, based on a combination between Earth Observation and in-situ data, would serve as basis the formalisation of a multi-hazard methodology, identifying gaps and research frontiers. Multi-hazard risk analysis is performed through the RASOR platform (Rapid Analysis and Spatialisation Of Risk). A scenario-driven query system allow users to simulate future scenarios based on existing and assumed conditions, to compare with historical scenarios, and to model multi-hazard risk both before and during an event (www.rasor.eu).

  2. Retrieval of constituent mixing ratios from limb thermal emission spectra

    NASA Technical Reports Server (NTRS)

    Shaffer, William A.; Kunde, Virgil G.; Conrath, Barney J.

    1988-01-01

    An onion-peeling iterative, least-squares relaxation method to retrieve mixing ratio profiles from limb thermal emission spectra is presented. The method has been tested on synthetic data, containing various amounts of added random noise for O3, HNO3, and N2O. The retrieval method is used to obtain O3 and HNO3 mixing ratio profiles from high-resolution thermal emission spectra. Results of the retrievals compare favorably with those obtained previously.

  3. Canister Storage Building (CSB) Hazard Analysis Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    POWERS, T.B.

    2000-03-16

    This report describes the methodology used in conducting the Canister Storage Building (CSB) Hazard Analysis to support the final CSB Safety Analysis Report and documents the results. This report describes the methodology used in conducting the Canister Storage Building (CSB) hazard analysis to support the CSB final safety analysis report (FSAR) and documents the results. The hazard analysis process identified hazardous conditions and material-at-risk, determined causes for potential accidents, identified preventive and mitigative features, and qualitatively estimated the frequencies and consequences of specific occurrences. The hazard analysis was performed by a team of cognizant CSB operations and design personnel, safetymore » analysts familiar with the CSB, and technical experts in specialty areas. The material included in this report documents the final state of a nearly two-year long process. Attachment A provides two lists of hazard analysis team members and describes the background and experience of each. The first list is a complete list of the hazard analysis team members that have been involved over the two-year long process. The second list is a subset of the first list and consists of those hazard analysis team members that reviewed and agreed to the final hazard analysis documentation. The material included in this report documents the final state of a nearly two-year long process involving formal facilitated group sessions and independent hazard and accident analysis work. The hazard analysis process led to the selection of candidate accidents for further quantitative analysis. New information relative to the hazards, discovered during the accident analysis, was incorporated into the hazard analysis data in order to compile a complete profile of facility hazards. Through this process, the results of the hazard and accident analyses led directly to the identification of safety structures, systems, and components, technical safety requirements, and

  4. Elevated sacroilac joint uptake ratios in systemic lupus erythematosus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    De Smet, A.A.; Mahmood, T.; Robinson, R.G.

    1984-08-01

    Sacroiliac joint radiographs and radionuclide sacroiliac joint uptake ratios were obtained on 14 patients with active systemic lupus erythematosus. Elevated joint ratios were found unilaterally in two patients and bilaterally in seven patients when their lupus was active. In patients whose disease became quiescent, the uptake ratios returned to normal. Two patients had persistently elevated ratios with continued clinical and laboratory evidence of active lupus. Mild sacroiliac joint sclerosis and erosions were detected on pelvic radiographs in these same two patients. Elevated quantitative sacroiliac joint uptake ratios may occur as a manifestation of active systemic lupus erythematosus.

  5. Change detection from synthetic aperture radar images based on neighborhood-based ratio and extreme learning machine

    NASA Astrophysics Data System (ADS)

    Gao, Feng; Dong, Junyu; Li, Bo; Xu, Qizhi; Xie, Cui

    2016-10-01

    Change detection is of high practical value to hazard assessment, crop growth monitoring, and urban sprawl detection. A synthetic aperture radar (SAR) image is the ideal information source for performing change detection since it is independent of atmospheric and sunlight conditions. Existing SAR image change detection methods usually generate a difference image (DI) first and use clustering methods to classify the pixels of DI into changed class and unchanged class. Some useful information may get lost in the DI generation process. This paper proposed an SAR image change detection method based on neighborhood-based ratio (NR) and extreme learning machine (ELM). NR operator is utilized for obtaining some interested pixels that have high probability of being changed or unchanged. Then, image patches centered at these pixels are generated, and ELM is employed to train a model by using these patches. Finally, pixels in both original SAR images are classified by the pretrained ELM model. The preclassification result and the ELM classification result are combined to form the final change map. The experimental results obtained on three real SAR image datasets and one simulated dataset show that the proposed method is robust to speckle noise and is effective to detect change information among multitemporal SAR images.

  6. USGS National Seismic Hazard Maps

    USGS Publications Warehouse

    Frankel, A.D.; Mueller, C.S.; Barnhard, T.P.; Leyendecker, E.V.; Wesson, R.L.; Harmsen, S.C.; Klein, F.W.; Perkins, D.M.; Dickman, N.C.; Hanson, S.L.; Hopper, M.G.

    2000-01-01

    The U.S. Geological Survey (USGS) recently completed new probabilistic seismic hazard maps for the United States, including Alaska and Hawaii. These hazard maps form the basis of the probabilistic component of the design maps used in the 1997 edition of the NEHRP Recommended Provisions for Seismic Regulations for New Buildings and Other Structures, prepared by the Building Seismic Safety Council arid published by FEMA. The hazard maps depict peak horizontal ground acceleration and spectral response at 0.2, 0.3, and 1.0 sec periods, with 10%, 5%, and 2% probabilities of exceedance in 50 years, corresponding to return times of about 500, 1000, and 2500 years, respectively. In this paper we outline the methodology used to construct the hazard maps. There are three basic components to the maps. First, we use spatially smoothed historic seismicity as one portion of the hazard calculation. In this model, we apply the general observation that moderate and large earthquakes tend to occur near areas of previous small or moderate events, with some notable exceptions. Second, we consider large background source zones based on broad geologic criteria to quantify hazard in areas with little or no historic seismicity, but with the potential for generating large events. Third, we include the hazard from specific fault sources. We use about 450 faults in the western United States (WUS) and derive recurrence times from either geologic slip rates or the dating of pre-historic earthquakes from trenching of faults or other paleoseismic methods. Recurrence estimates for large earthquakes in New Madrid and Charleston, South Carolina, were taken from recent paleoliquefaction studies. We used logic trees to incorporate different seismicity models, fault recurrence models, Cascadia great earthquake scenarios, and ground-motion attenuation relations. We present disaggregation plots showing the contribution to hazard at four cities from potential earthquakes with various magnitudes and

  7. Preliminary hazards analysis -- vitrification process

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Coordes, D.; Ruggieri, M.; Russell, J.

    1994-06-01

    This paper presents a Preliminary Hazards Analysis (PHA) for mixed waste vitrification by joule heating. The purpose of performing a PHA is to establish an initial hazard categorization for a DOE nuclear facility and to identify those processes and structures which may have an impact on or be important to safety. The PHA is typically performed during and provides input to project conceptual design. The PHA is then followed by a Preliminary Safety Analysis Report (PSAR) performed during Title 1 and 2 design. The PSAR then leads to performance of the Final Safety Analysis Report performed during the facility`s constructionmore » and testing. It should be completed before routine operation of the facility commences. This PHA addresses the first four chapters of the safety analysis process, in accordance with the requirements of DOE Safety Guidelines in SG 830.110. The hazards associated with vitrification processes are evaluated using standard safety analysis methods which include: identification of credible potential hazardous energy sources; identification of preventative features of the facility or system; identification of mitigative features; and analyses of credible hazards. Maximal facility inventories of radioactive and hazardous materials are postulated to evaluate worst case accident consequences. These inventories were based on DOE-STD-1027-92 guidance and the surrogate waste streams defined by Mayberry, et al. Radiological assessments indicate that a facility, depending on the radioactive material inventory, may be an exempt, Category 3, or Category 2 facility. The calculated impacts would result in no significant impact to offsite personnel or the environment. Hazardous materials assessment indicates that a Mixed Waste Vitrification facility will be a Low Hazard facility having minimal impacts to offsite personnel and the environment.« less

  8. Wake-Vortex Hazards During Cruise

    NASA Technical Reports Server (NTRS)

    Rossow, Vernon J.; James, Kevin D.; Nixon, David (Technical Monitor)

    1998-01-01

    Even though the hazard posed by lift-generated wakes of subsonic transport aircraft has been studied extensively for approach and departure at airports, only a small amount of effort has gone into the potential hazard at cruise altitude. This paper reports on a studio of the wake-vortex hazard during cruise because encounters may become more prevalent when free-flight becomes available and each aircraft, is free to choose its own route between destinations. In order to address the problem, the various fluid-dynamic stages that vortex wakes usually go through as they age will be described along with estimates of the potential hazard that each stage poses. It appears that a rolling-moment hazard can be just as severe at cruise as for approach at airports, but it only persists for several minutes. However, the hazard posed by the downwash in the wake due to the lift on the generator aircraft persists for tens of minutes in a long narrow region behind the generating aircraft. The hazard consists of severe vertical loads when an encountering aircraft crosses the wake. A technique for avoiding vortex wakes at cruise altitude will be described. To date the hazard posed by lift-generated vortex wakes and their persistence at cruise altitudes has been identified and subdivided into several tasks. Analyses of the loads to be encounter and are underway and should be completed shortly. A review of published literature on the subject has been nearly completed (see text) and photographs of vortex wakes at cruise altitudes have been taken and the various stages of decay have been identified. It remains to study and sort the photographs for those that best illustrate the various stages of decay after they are shed by subsonic transport aircraft at cruise altitudes. The present status of the analysis and the paper are described.

  9. Hazards on Hazards, Ensuring Spacecraft Safety While Sampling Asteroid Surface Materials

    NASA Astrophysics Data System (ADS)

    Johnson, C. A.; DellaGiustina, D. N.

    2016-12-01

    The near-Earth object Bennu is a carbonaceous asteroid that is a remnant from the earliest stages of the solar-system formation. It is also a potentially hazardous asteroid with a relatively high probability of impacting Earth late in the 22nd century. While the primary focus of the NASA funded OSIRIS-REx mission is the return of pristine organic material from the asteroid's surface, information about Bennu's physical and chemical properties gleaned throughout operations will be critical for a possible future impact mitigation mission. In order to ensure a regolith sample can be successfully acquired, the sample site and surrounding area must be thoroughly assessed for any potential hazards to the spacecraft. The OSIRIS-REx Image Processing Working Group has been tasked with generating global and site-specific hazard maps using mosaics and a trio of fea­­­ture identification techniques. These techniques include expert-lead manual classification, internet-based amateur classification using the citizen science platform CosmoQuest, and automated classification using machine learning and computer vision tools. Because proximity operations around Bennu do not begin until the end of 2018, we have an opportunity to test t­­­he performance of our software on analogue surfaces of other asteroids from previous NASA and other space agencies missions. The entire pipeline from image processing and mosaicking to hazard identification, analysis and mapping will be performed on asteroids of varying size, shape and surface morphology. As a result, upon arrival at Bennu, we will have the software and processes in place to quickly and confidently produce the hazard maps needed to ensure the success of our mission.

  10. A situational analysis of priority disaster hazards in Uganda: findings from a hazard and vulnerability analysis.

    PubMed

    Mayega, R W; Wafula, M R; Musenero, M; Omale, A; Kiguli, J; Orach, G C; Kabagambe, G; Bazeyo, W

    2013-06-01

    Most countries in sub-Saharan Africa have not conducted a disaster risk analysis. Hazards and vulnerability analyses provide vital information that can be used for development of risk reduction and disaster response plans. The purpose of this study was to rank disaster hazards for Uganda, as a basis for identifying the priority hazards to guide disaster management planning. The study as conducted in Uganda, as part of a multi-country assessment. A hazard, vulnerability and capacity analysis was conducted in a focus group discussion of 7 experts representing key stakeholder agencies in disaster management in Uganda. A simple ranking method was used to rank the probability of occurance of 11 top hazards, their potential impact and the level vulnerability of people and infrastructure. In-terms of likelihood of occurance and potential impact, the top ranked disaster hazards in Uganda are: 1) Epidemics of infectious diseases, 2) Drought/famine, 3) Conflict and environmental degradation in that order. In terms of vulnerability, the top priority hazards to which people and infrastructure were vulnerable were: 1) Conflicts, 2) Epidemics, 3) Drought/famine and, 4) Environmental degradation in that order. Poverty, gender, lack of information, and lack of resilience measures were some of the factors promoting vulnerability to disasters. As Uganda develops a disaster risk reduction and response plan, it ought to prioritize epidemics of infectious diseases, drought/famine, conflics and environmental degradation as the priority disaster hazards.

  11. Natural Hazards In Mexico City

    NASA Astrophysics Data System (ADS)

    Torres-Vera, M.

    2001-12-01

    earthquakes. This information was used to generate maps, which delimited zones that may suffer damage by rain, fire or earthquake. The convolution of the obtained maps produces a map of the city, where the areas with higher probability to suffer a hazard are defined. These results can be used to propose land use planning to avoid the growth of urban areas in high-risk zones.

  12. Probabilistic Tsunami Hazard Assessment: the Seaside, Oregon Pilot Study

    NASA Astrophysics Data System (ADS)

    Gonzalez, F. I.; Geist, E. L.; Synolakis, C.; Titov, V. V.

    2004-12-01

    events could benefit the NTHMP. The joint NFIP/NTHMP pilot study at Seaside, Oregon is organized into three closely related components: Probabilistic, Modeling, and Impact studies. Probabilistic studies (Geist, et al., this session) are led by the USGS and include the specification of near- and far-field seismic tsunami sources and their associated probabilities. Modeling studies (Titov, et al., this session) are led by NOAA and include the development and testing of a Seaside tsunami inundation model and an associated database of computed wave height and flow velocity fields. Impact studies (Synolakis, et al., this session) are led by USC and include the computation and analyses of indices for the categorization of hazard zones. The results of each component study will be integrated to produce a Seaside tsunami hazard map. This presentation will provide a brief overview of the project and an update on progress, while the above-referenced companion presentations will provide details on the methods used and the preliminary results obtained by each project component.

  13. Assessment of natural radionuclides and its radiological hazards from tiles made in Nigeria

    NASA Astrophysics Data System (ADS)

    Joel, E. S.; Maxwell, O.; Adewoyin, O. O.; Ehi-Eromosele, C. O.; Embong, Z.; Saeed, M. A.

    2018-03-01

    Activity concentration of 10 different brands of tiles made in Nigeria were analyzed using High purity Germanium gamma detector and its hazard indices such as absorbed dose rate, radium equivalent activity, external Hazard Index (Hex), internal Hazard Index (Hin), Annual Effective Dose (mSv/y), Gamma activity Index (Iγ) and Alpha Index (Iα) were determined. The result showed that the average activity concentrations of radionuclides (226Ra, 232Th and 40K) content are within the recommended limit. The average radium equivalent is within the recommended limit of 370 Bq/kg. The result obtained further showed that the mean values for the absorbed dose rate (D), external and internal hazard index, the annual effective dose (AEDR) equivalent, gamma activity index and Alpha Index were: 169.22 nGyh-1, 0.95 and 1.14, 1.59 mSv/y, 1.00 Sv yr-1 and 0.34 respectively. The result established that radiological hazards such as absorbed dose rate, internal hazard, annual effective dose rate, gamma activity index and Alpha Index for some samples are found to be slightly close or above international recommended values. The result for the present study was compared with tiles sample from others countries, it was observed that the concentration of tiles made in Nigeria and other countries are closer, however recommends proper radiation monitoring for some tiles made in Nigeria before usage due to the long term health effect.

  14. Avoiding the Hazards of Hazardous Waste.

    ERIC Educational Resources Information Center

    Hiller, Richard

    1996-01-01

    Under a 1980 law, colleges and universities can be liable for cleanup of hazardous waste on properties, in companies, and related to stocks they invest in or are given. College planners should establish clear policy concerning gifts, investigate gifts, distance university from business purposes, sell real estate gifts quickly, consult a risk…

  15. New insights on the seismic hazard in the Balkans inferred from GPS

    NASA Astrophysics Data System (ADS)

    D'Agostino, Nicola; Métois, Marianne; Avallone, Antonio; Chamot-Rooke, Nicolas

    2014-05-01

    associated seismic hazard of the Balkan region. We processed all the currently available data acquired on these new networks using the precise point positioning strategy of the Gipsy-Oasis software (Bertiger et al. 2010) and the daily ITF2008 transformation parameters (x-files) from JPL. Daily coordinates are obtained in a Eurasia-fix reference frame obtained using the strategy developed by Blewitt et al. (2012). Here we present this new velocity field combined with previously published data sets covering the Balkan Peninsula. This unusually dense picture of the current deformation, in particular in Slovenia and Serbia, enables us to derive a continuous map of the strain rate over the region using the approach of Haines and Holt (1993). We then derive the seismogenic potential of the region combining the geodetic strain rate and the available regional CMT moment tensor solutions. These maps bring new insights on areas of significant strain accumulation over the Balkan Peninsula and are a first step to better assess seismic hazard there.

  16. Considering the ranges of uncertainties in the New Probabilistic Seismic Hazard Assessment of Germany - Version 2016

    NASA Astrophysics Data System (ADS)

    Grunthal, Gottfried; Stromeyer, Dietrich; Bosse, Christian; Cotton, Fabrice; Bindi, Dino

    2017-04-01

    The seismic load parameters for the upcoming National Annex to the Eurocode 8 result from the reassessment of the seismic hazard supported by the German Institution for Civil Engineering . This 2016 version of hazard assessment for Germany as target area was based on a comprehensive involvement of all accessible uncertainties in models and parameters into the approach and the provision of a rational framework for facilitating the uncertainties in a transparent way. The developed seismic hazard model represents significant improvements; i.e. it is based on updated and extended databases, comprehensive ranges of models, robust methods and a selection of a set of ground motion prediction equations of their latest generation. The output specifications were designed according to the user oriented needs as suggested by two review teams supervising the entire project. In particular, seismic load parameters were calculated for rock conditions with a vS30 of 800 ms-1 for three hazard levels (10%, 5% and 2% probability of occurrence or exceedance within 50 years) in form of, e.g., uniform hazard spectra (UHS) based on 19 sprectral periods in the range of 0.01 - 3s, seismic hazard maps for spectral response accelerations for different spectral periods or for macroseismic intensities. The developed hazard model consists of a logic tree with 4040 end branches and essential innovations employed to capture epistemic uncertainties and aleatory variabilities. The computation scheme enables the sound calculation of the mean and any quantile of required seismic load parameters. Mean, median and 84th percentiles of load parameters were provided together with the full calculation model to clearly illustrate the uncertainties of such a probabilistic assessment for a region of a low-to-moderate level of seismicity. The regional variations of these uncertainties (e.g. ratios between the mean and median hazard estimations) were analyzed and discussed.

  17. Applying Additive Hazards Models for Analyzing Survival in Patients with Colorectal Cancer in Fars Province, Southern Iran

    PubMed

    Madadizadeh, Farzan; Ghanbarnejad, Amin; Ghavami, Vahid; Zare Bandamiri, Mohammad; Mohammadianpanah, Mohammad

    2017-04-01

    Introduction: Colorectal cancer (CRC) is a commonly fatal cancer that ranks as third worldwide and third and the fifth in Iranian women and men, respectively. There are several methods for analyzing time to event data. Additive hazards regression models take priority over the popular Cox proportional hazards model if the absolute hazard (risk) change instead of hazard ratio is of primary concern, or a proportionality assumption is not made. Methods: This study used data gathered from medical records of 561 colorectal cancer patients who were admitted to Namazi Hospital, Shiraz, Iran, during 2005 to 2010 and followed until December 2015. The nonparametric Aalen’s additive hazards model, semiparametric Lin and Ying’s additive hazards model and Cox proportional hazards model were applied for data analysis. The proportionality assumption for the Cox model was evaluated with a test based on the Schoenfeld residuals and for test goodness of fit in additive models, Cox-Snell residual plots were used. Analyses were performed with SAS 9.2 and R3.2 software. Results: The median follow-up time was 49 months. The five-year survival rate and the mean survival time after cancer diagnosis were 59.6% and 68.1±1.4 months, respectively. Multivariate analyses using Lin and Ying’s additive model and the Cox proportional model indicated that the age of diagnosis, site of tumor, stage, and proportion of positive lymph nodes, lymphovascular invasion and type of treatment were factors affecting survival of the CRC patients. Conclusion: Additive models are suitable alternatives to the Cox proportionality model if there is interest in evaluation of absolute hazard change, or no proportionality assumption is made. Creative Commons Attribution License

  18. Success in transmitting hazard science

    NASA Astrophysics Data System (ADS)

    Price, J. G.; Garside, T.

    2010-12-01

    Money motivates mitigation. An example of success in communicating scientific information about hazards, coupled with information about available money, is the follow-up action by local governments to actually mitigate. The Nevada Hazard Mitigation Planning Committee helps local governments prepare competitive proposals for federal funds to reduce risks from natural hazards. Composed of volunteers with expertise in emergency management, building standards, and earthquake, flood, and wildfire hazards, the committee advises the Nevada Division of Emergency Management on (1) the content of the State’s hazard mitigation plan and (2) projects that have been proposed by local governments and state agencies for funding from various post- and pre-disaster hazard mitigation programs of the Federal Emergency Management Agency. Local governments must have FEMA-approved hazard mitigation plans in place before they can receive this funding. The committee has been meeting quarterly with elected and appointed county officials, at their offices, to encourage them to update their mitigation plans and apply for this funding. We have settled on a format that includes the county’s giving the committee an overview of its infrastructure, hazards, and preparedness. The committee explains the process for applying for mitigation grants and presents the latest information that we have about earthquake hazards, including locations of nearby active faults, historical seismicity, geodetic strain, loss-estimation modeling, scenarios, and documents about what to do before, during, and after an earthquake. Much of the county-specific information is available on the web. The presentations have been well received, in part because the committee makes the effort to go to their communities, and in part because the committee is helping them attract federal funds for local mitigation of not only earthquake hazards but also floods (including canal breaches) and wildfires, the other major concerns in

  19. Constraints on Long-Term Seismic Hazard From Vulnerable Stalagmites

    NASA Astrophysics Data System (ADS)

    Gribovszki, Katalin; Bokelmann, Götz; Mónus, Péter; Kovács, Károly; Konecny, Pavel; Lednicka, Marketa; Bednárik, Martin; Brimich, Ladislav

    2015-04-01

    Earthquakes hit urban centers in Europe infrequently, but occasionally with disastrous effects. This raises the important issue for society, how to react to the natural hazard: potential damages are huge, but infrastructure costs for addressing these hazards are huge as well. Furthermore, seismic hazard is only one of the many hazards facing society. Societal means need to be distributed in a reasonable manner - to assure that all of these hazards (natural as well as societal) are addressed appropriately. Obtaining an unbiased view of seismic hazard (and risk) is very important therefore. In principle, the best way to test PSHA models is to compare with observations that are entirely independent of the procedure used to produce the PSHA models. Arguably, the most valuable information in this context should be information on long-term hazard, namely maximum intensities (or magnitudes) occuring over time intervals that are at least as long as a seismic cycle - if that exists. Such information would be very valuable, even if it concerned only a single site, namely that of a particularly sensitive infrastructure. Such a request may seem hopeless - but it is not. Long-term information can in principle be gained from intact stalagmites in natural caves. These have survived all earthquakes that have occurred, over thousands of years - depending on the age of the stalagmite. Their "survival" requires that the horizontal ground acceleration has never exceeded a certain critical value within that period. We are focusing here on case studies in Austria, which has moderate seismicity, but a well-documented history of major earthquake-induced damage, e.g., Villach in 1348 and 1690, Vienna in 1590, Leoben in 1794, and Innsbruck in 1551, 1572, and 1589. Seismic intensities have reached levels up to 10. It is clearly important to know which "worst-case" damages to expect. We have identified sets of particularly sensitive stalagmites in the general vicinity of two major cities in

  20. Relationship between chemical structure and the occupational asthma hazard of low molecular weight organic compounds

    PubMed Central

    Jarvis, J; Seed, M; Elton, R; Sawyer, L; Agius, R

    2005-01-01

    Aims: To investigate quantitatively, relationships between chemical structure and reported occupational asthma hazard for low molecular weight (LMW) organic compounds; to develop and validate a model linking asthma hazard with chemical substructure; and to generate mechanistic hypotheses that might explain the relationships. Methods: A learning dataset used 78 LMW chemical asthmagens reported in the literature before 1995, and 301 control compounds with recognised occupational exposures and hazards other than respiratory sensitisation. The chemical structures of the asthmagens and control compounds were characterised by the presence of chemical substructure fragments. Odds ratios were calculated for these fragments to determine which were associated with a likelihood of being reported as an occupational asthmagen. Logistic regression modelling was used to identify the independent contribution of these substructures. A post-1995 set of 21 asthmagens and 77 controls were selected to externally validate the model. Results: Nitrogen or oxygen containing functional groups such as isocyanate, amine, acid anhydride, and carbonyl were associated with an occupational asthma hazard, particularly when the functional group was present twice or more in the same molecule. A logistic regression model using only statistically significant independent variables for occupational asthma hazard correctly assigned 90% of the model development set. The external validation showed a sensitivity of 86% and specificity of 99%. Conclusions: Although a wide variety of chemical structures are associated with occupational asthma, bifunctional reactivity is strongly associated with occupational asthma hazard across a range of chemical substructures. This suggests that chemical cross-linking is an important molecular mechanism leading to the development of occupational asthma. The logistic regression model is freely available on the internet and may offer a useful but inexpensive adjunct to the

  1. Aortic Cross-Sectional Area/Height Ratio and Outcomes in Patients With Bicuspid Aortic Valve and a Dilated Ascending Aorta.

    PubMed

    Masri, Ahmad; Kalahasti, Vidyasagar; Svensson, Lars G; Alashi, Alaa; Schoenhagen, Paul; Roselli, Eric E; Johnston, Douglas R; Rodriguez, L Leonardo; Griffin, Brian P; Desai, Milind Y

    2017-06-01

    In patients with bicuspid aortic valve and dilated proximal ascending aorta, we sought to assess (1) factors associated with increased longer-term cardiovascular mortality and (2) incremental prognostic use of indexing aortic root to patient height. We studied 969 consecutive bicuspid aortic valve patients (50±13 years; 87% men) with proximal aorta ≥4 cm, who also had a gated contrast-enhanced thoracic computed tomography or magnetic resonance angiography. A ratio of ascending aortic area/height was calculated on tomography, and ≥10 cm 2 /m was considered abnormal, as previously reported. Society of Thoracic Surgeons score and cardiovascular death were recorded. Greater than or equal to III+ aortic regurgitation and severe aortic stenosis were seen in 37% and 10%, respectively. Society of Thoracic Surgeons score and right ventricular systolic pressure were 2±3 and 15±16 mm Hg, respectively. Abnormal ascending aortic area/height ratio was noted in 33%; 44% underwent ascending aortic surgery at 34 days. At 10.8 years (interquartile range, 9.6-12.3), 82 (9%) died (0.4% in-hospital postoperative mortality). On multivariable Cox survival analysis, ascending aortic area/height ratio (hazard ratio, 2; 95% confidence interval, 1.20-3.35) was associated with cardiovascular death, whereas aortic surgery (hazard ratio, 0.46; confidence interval, 0.26-0.80) was associated with improved survival (both P <0.01). Of the 405 patients with ascending aortic diameter of 4.5 to 5.5 cm, 64% had an abnormal ascending aortic area/height ratio, and 70% deaths occurred in patients with an abnormal ratio. In bicuspid aortic valve patients with dilated proximal ascending aorta, ascending aortic area/height ratio was independently associated with cardiovascular death. © 2017 American Heart Association, Inc.

  2. Natural Hazards within the West Indies.

    ERIC Educational Resources Information Center

    Cross, John A.

    1992-01-01

    Outlines the vulnerability of the West Indies to various natural hazards, especially hurricanes, earthquakes, and volcanic eruptions. Reviews the geologic and meteorologic causes and consequences of the hazards. Suggests methods of incorporating hazards information in geography classes. Includes maps and a hurricane tracking chart. (DK)

  3. 30 CFR 47.21 - Identifying hazardous chemicals.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 30 Mineral Resources 1 2011-07-01 2011-07-01 false Identifying hazardous chemicals. 47.21 Section... TRAINING HAZARD COMMUNICATION (HazCom) Hazard Determination § 47.21 Identifying hazardous chemicals. The operator must evaluate each chemical brought on mine property and each chemical produced on mine property...

  4. 30 CFR 47.21 - Identifying hazardous chemicals.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Identifying hazardous chemicals. 47.21 Section... TRAINING HAZARD COMMUNICATION (HazCom) Hazard Determination § 47.21 Identifying hazardous chemicals. The operator must evaluate each chemical brought on mine property and each chemical produced on mine property...

  5. 30 CFR 47.21 - Identifying hazardous chemicals.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 30 Mineral Resources 1 2013-07-01 2013-07-01 false Identifying hazardous chemicals. 47.21 Section... TRAINING HAZARD COMMUNICATION (HazCom) Hazard Determination § 47.21 Identifying hazardous chemicals. The operator must evaluate each chemical brought on mine property and each chemical produced on mine property...

  6. 30 CFR 47.21 - Identifying hazardous chemicals.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 30 Mineral Resources 1 2012-07-01 2012-07-01 false Identifying hazardous chemicals. 47.21 Section... TRAINING HAZARD COMMUNICATION (HazCom) Hazard Determination § 47.21 Identifying hazardous chemicals. The operator must evaluate each chemical brought on mine property and each chemical produced on mine property...

  7. 30 CFR 47.21 - Identifying hazardous chemicals.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 30 Mineral Resources 1 2014-07-01 2014-07-01 false Identifying hazardous chemicals. 47.21 Section... TRAINING HAZARD COMMUNICATION (HazCom) Hazard Determination § 47.21 Identifying hazardous chemicals. The operator must evaluate each chemical brought on mine property and each chemical produced on mine property...

  8. Application of decision tree model for the ground subsidence hazard mapping near abandoned underground coal mines.

    PubMed

    Lee, Saro; Park, Inhye

    2013-09-30

    Subsidence of ground caused by underground mines poses hazards to human life and property. This study analyzed the hazard to ground subsidence using factors that can affect ground subsidence and a decision tree approach in a geographic information system (GIS). The study area was Taebaek, Gangwon-do, Korea, where many abandoned underground coal mines exist. Spatial data, topography, geology, and various ground-engineering data for the subsidence area were collected and compiled in a database for mapping ground-subsidence hazard (GSH). The subsidence area was randomly split 50/50 for training and validation of the models. A data-mining classification technique was applied to the GSH mapping, and decision trees were constructed using the chi-squared automatic interaction detector (CHAID) and the quick, unbiased, and efficient statistical tree (QUEST) algorithms. The frequency ratio model was also applied to the GSH mapping for comparing with probabilistic model. The resulting GSH maps were validated using area-under-the-curve (AUC) analysis with the subsidence area data that had not been used for training the model. The highest accuracy was achieved by the decision tree model using CHAID algorithm (94.01%) comparing with QUEST algorithms (90.37%) and frequency ratio model (86.70%). These accuracies are higher than previously reported results for decision tree. Decision tree methods can therefore be used efficiently for GSH analysis and might be widely used for prediction of various spatial events. Copyright © 2013. Published by Elsevier Ltd.

  9. A Model for Generating Multi-hazard Scenarios

    NASA Astrophysics Data System (ADS)

    Lo Jacomo, A.; Han, D.; Champneys, A.

    2017-12-01

    Communities in mountain areas are often subject to risk from multiple hazards, such as earthquakes, landslides, and floods. Each hazard has its own different rate of onset, duration, and return period. Multiple hazards tend to complicate the combined risk due to their interactions. Prioritising interventions for minimising risk in this context is challenging. We developed a probabilistic multi-hazard model to help inform decision making in multi-hazard areas. The model is applied to a case study region in the Sichuan province in China, using information from satellite imagery and in-situ data. The model is not intended as a predictive model, but rather as a tool which takes stakeholder input and can be used to explore plausible hazard scenarios over time. By using a Monte Carlo framework and varrying uncertain parameters for each of the hazards, the model can be used to explore the effect of different mitigation interventions aimed at reducing the disaster risk within an uncertain hazard context.

  10. Reviewing and visualizing the interactions of natural hazards

    NASA Astrophysics Data System (ADS)

    Gill, Joel C.; Malamud, Bruce D.

    2014-12-01

    This paper presents a broad overview, characterization, and visualization of the interaction relationships between 21 natural hazards, drawn from six hazard groups (geophysical, hydrological, shallow Earth, atmospheric, biophysical, and space hazards). A synthesis is presented of the identified interaction relationships between these hazards, using an accessible visual format particularly suited to end users. Interactions considered are primarily those where a primary hazard triggers or increases the probability of secondary hazards occurring. In this paper we do the following: (i) identify, through a wide-ranging review of grey- and peer-review literature, 90 interactions; (ii) subdivide the interactions into three levels, based on how well we can characterize secondary hazards, given information about the primary hazard; (iii) determine the spatial overlap and temporal likelihood of the triggering relationships occurring; and (iv) examine the relationship between primary and secondary hazard intensities for each identified hazard interaction and group these into five possible categories. In this study we have synthesized, using accessible visualization techniques, large amounts of information drawn from many scientific disciplines. We outline the importance of constraining hazard interactions and reinforce the importance of a holistic (or multihazard) approach to natural hazard assessment. This approach allows those undertaking research into single hazards to place their work within the context of other hazards. It also communicates important aspects of hazard interactions, facilitating an effective analysis by those working on reducing and managing disaster risk within both the policy and practitioner communities.

  11. The Nature of Natural Hazards Communication (Invited)

    NASA Astrophysics Data System (ADS)

    Kontar, Y. Y.

    2013-12-01

    Some of the many issues of interest to natural hazards professionals include the analysis of proactive approaches to the governance of risk from natural hazards and approaches to broaden the scope of public policies related to the management of risks from natural hazards, as well as including emergency and environmental management, community development and spatial planning related to natural hazards. During the talk we will present results of scientific review, analysis and synthesis, which emphasize same new trends in communication of the natural hazards theories and practices within an up-to-the-minute context of new environmental and climate change issues, new technologies, and a new focus on resiliency. The presentation is divided into five sections that focus on natural hazards communication in terms of education, risk management, public discourse, engaging the public, theoretical perspectives, and new media. It includes results of case studies and best practices. It delves into natural hazards communication theories, including diffusion, argumentation, and constructivism, to name a few. The presentation will provide information about: (1) A manual of natural hazards communication for scientists, policymakers, and media; (2) An up-to-the-minute context of environmental hazards, new technologies & political landscape; (3) A work by natural hazards scientists for geoscientists working with social scientists and communication principles; (4) A work underpinned by key natural hazards communication theories and interspersed with pragmatic solutions; (5) A work that crosses traditional natural hazards boundaries: international, interdisciplinary, theoretical/applied. We will further explore how spatial planning can contribute to risk governance by influencing the occupation of natural hazard-prone areas, and review the central role of emergency management in risk policy. The goal of this presentation is to contribute to the augmentation of the conceptual framework

  12. Environmental management of industrial hazardous wastes in India.

    PubMed

    Dutta, Shantanu K; Upadhyay, V P; Sridharan, U

    2006-04-01

    Hazardous wastes are considered highly toxic and therefore disposal of such wastes needs proper attention so as to reduce possible environmental hazards. Industrial growth has resulted in generation of huge volume of hazardous wastes in the country. In addition to this, hazardous wastes sometimes get imported mainly from the western countries for re-processing or recycling. Inventorisation of hazardous wastes generating units in the country is not yet completed. Scientific disposal of hazardous wastes has become a major environmental issue in India. Hazardous Wastes (Management and Handling) Rules, 1989 have been framed by the Central Government and amended in 2000 and 2003 to deal with the hazardous wastes related environmental problems that may arise in the near future. This paper gives details about the hazardous wastes management in India. Health effects of the selected hazardous substances are also discussed in the paper.

  13. Comparison of landslide hazard and risk assessment practices in Europe

    NASA Astrophysics Data System (ADS)

    Corominas, J.; Mavrouli, O.

    2012-04-01

    An overview is made of the landslide hazard and risk assessment practices that are officially promoted or applied in Europe by administration offices, geological surveys, and decision makers (recommendations, regulations and codes). The reported countries are: Andorra, Austria, France, Italy (selected river basins), Romania, Spain (Catalonia), Switzerland and United Kingdom. The objective here was to compare the different practices for hazard and risk evaluation with respect to the official policies, the methodologies used (qualitative and quantitative), the provided outputs and their contents, and the terminology and map symbols used. The main observations made are illustrated with examples and the possibility of harmonization of the policies and the application of common practices to bridge the existing gaps is discussed. Some of the conclusions reached include the following: zoning maps are legally binding for public administrators and land owners only in some cases and generally when referring to site-specific or local scales rather than regional or national ones; so far, information is mainly provided on landslide susceptibility and hazard and risk assessment is performed only in a few countries; there is a variation in the use of scales between countries; the classification criteria for landslide types and mechanisms present large diversity even within the same country (in some cases no landslide mechanisms are specified while in others there is an exhaustive list); the techniques to obtain input data for the landslide inventory and susceptibility maps vary from basic to sophisticated, resulting in various levels of data quality and quantity; the procedures followed for hazard and risk assessment include analytical procedures supported by computer simulation, weighted-indicators, expert judgment and field survey-based, or a combination of all; there is an important variation between hazard and risk matrices with respect to the used parameters, the thresholds

  14. Augmenting the logrank test in the design of clinical trials in which non-proportional hazards of the treatment effect may be anticipated.

    PubMed

    Royston, Patrick; Parmar, Mahesh K B

    2016-02-11

    Most randomized controlled trials with a time-to-event outcome are designed assuming proportional hazards (PH) of the treatment effect. The sample size calculation is based on a logrank test. However, non-proportional hazards are increasingly common. At analysis, the estimated hazards ratio with a confidence interval is usually presented. The estimate is often obtained from a Cox PH model with treatment as a covariate. If non-proportional hazards are present, the logrank and equivalent Cox tests may lose power. To safeguard power, we previously suggested a 'joint test' combining the Cox test with a test of non-proportional hazards. Unfortunately, a larger sample size is needed to preserve power under PH. Here, we describe a novel test that unites the Cox test with a permutation test based on restricted mean survival time. We propose a combined hypothesis test based on a permutation test of the difference in restricted mean survival time across time. The test involves the minimum of the Cox and permutation test P-values. We approximate its null distribution and correct it for correlation between the two P-values. Using extensive simulations, we assess the type 1 error and power of the combined test under several scenarios and compare with other tests. We investigate powering a trial using the combined test. The type 1 error of the combined test is close to nominal. Power under proportional hazards is slightly lower than for the Cox test. Enhanced power is available when the treatment difference shows an 'early effect', an initial separation of survival curves which diminishes over time. The power is reduced under a 'late effect', when little or no difference in survival curves is seen for an initial period and then a late separation occurs. We propose a method of powering a trial using the combined test. The 'insurance premium' offered by the combined test to safeguard power under non-PH represents about a single-digit percentage increase in sample size. The

  15. Seismic Hazard analysis of Adjaria Region in Georgia

    NASA Astrophysics Data System (ADS)

    Jorjiashvili, Nato; Elashvili, Mikheil

    2014-05-01

    The most commonly used approach to determining seismic-design loads for engineering projects is probabilistic seismic-hazard analysis (PSHA). The primary output from a PSHA is a hazard curve showing the variation of a selected ground-motion parameter, such as peak ground acceleration (PGA) or spectral acceleration (SA), against the annual frequency of exceedance (or its reciprocal, return period). The design value is the ground-motion level that corresponds to a preselected design return period. For many engineering projects, such as standard buildings and typical bridges, the seismic loading is taken from the appropriate seismic-design code, the basis of which is usually a PSHA. For more important engineering projects— where the consequences of failure are more serious, such as dams and chemical plants—it is more usual to obtain the seismic-design loads from a site-specific PSHA, in general, using much longer return periods than those governing code based design. Calculation of Probabilistic Seismic Hazard was performed using Software CRISIS2007 by Ordaz, M., Aguilar, A., and Arboleda, J., Instituto de Ingeniería, UNAM, Mexico. CRISIS implements a classical probabilistic seismic hazard methodology where seismic sources can be modelled as points, lines and areas. In the case of area sources, the software offers an integration procedure that takes advantage of a triangulation algorithm used for seismic source discretization. This solution improves calculation efficiency while maintaining a reliable description of source geometry and seismicity. Additionally, supplementary filters (e.g. fix a sitesource distance that excludes from calculation sources at great distance) allow the program to balance precision and efficiency during hazard calculation. Earthquake temporal occurrence is assumed to follow a Poisson process, and the code facilitates two types of MFDs: a truncated exponential Gutenberg-Richter [1944] magnitude distribution and a characteristic magnitude

  16. Revision of Time-Independent Probabilistic Seismic Hazard Maps for Alaska

    USGS Publications Warehouse

    Wesson, Robert L.; Boyd, Oliver S.; Mueller, Charles S.; Bufe, Charles G.; Frankel, Arthur D.; Petersen, Mark D.

    2007-01-01

    We present here time-independent probabilistic seismic hazard maps of Alaska and the Aleutians for peak ground acceleration (PGA) and 0.1, 0.2, 0.3, 0.5, 1.0 and 2.0 second spectral acceleration at probability levels of 2 percent in 50 years (annual probability of 0.000404), 5 percent in 50 years (annual probability of 0.001026) and 10 percent in 50 years (annual probability of 0.0021). These maps represent a revision of existing maps based on newly obtained data and assumptions reflecting best current judgments about methodology and approach. These maps have been prepared following the procedures and assumptions made in the preparation of the 2002 National Seismic Hazard Maps for the lower 48 States. A significant improvement relative to the 2002 methodology is the ability to include variable slip rate along a fault where appropriate. These maps incorporate new data, the responses to comments received at workshops held in Fairbanks and Anchorage, Alaska, in May, 2005, and comments received after draft maps were posted on the National Seismic Hazard Mapping Web Site. These maps will be proposed for adoption in future revisions to the International Building Code. In this documentation we describe the maps and in particular explain and justify changes that have been made relative to the 1999 maps. We are also preparing a series of experimental maps of time-dependent hazard that will be described in future documents.

  17. 16 CFR 1306.3 - Banned hazardous products.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... 16 Commercial Practices 2 2014-01-01 2014-01-01 false Banned hazardous products. 1306.3 Section 1306.3 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS BAN OF HAZARDOUS LAWN DARTS § 1306.3 Banned hazardous products. Any lawn dart is a banned hazardous...

  18. 16 CFR 1306.3 - Banned hazardous products.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 16 Commercial Practices 2 2012-01-01 2012-01-01 false Banned hazardous products. 1306.3 Section 1306.3 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS BAN OF HAZARDOUS LAWN DARTS § 1306.3 Banned hazardous products. Any lawn dart is a banned hazardous...

  19. 16 CFR 1306.3 - Banned hazardous products.

    Code of Federal Regulations, 2010 CFR

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Banned hazardous products. 1306.3 Section 1306.3 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS BAN OF HAZARDOUS LAWN DARTS § 1306.3 Banned hazardous products. Any lawn dart is a banned hazardous...

  20. 16 CFR 1306.3 - Banned hazardous products.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... 16 Commercial Practices 2 2011-01-01 2011-01-01 false Banned hazardous products. 1306.3 Section 1306.3 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS BAN OF HAZARDOUS LAWN DARTS § 1306.3 Banned hazardous products. Any lawn dart is a banned hazardous...

  1. A Natural Hazards Workbook.

    ERIC Educational Resources Information Center

    Kohler, Fred

    This paper discusses the development of and provides examples of exercises from a student workbook for a college-level course about natural hazards. The course is offered once a year to undergraduates at Western Illinois University. Students are introduced to 10 hazards (eight meteorological plus earthquakes and volcanoes) through slides, movies,…

  2. Prognostic value of serum heavy/light chain ratios in patients with POEMS syndrome.

    PubMed

    Wang, Chen; Su, Wei; Cai, Qian-Qian; Cai, Hao; Ji, Wei; Di, Qian; Duan, Ming-Hui; Cao, Xin-Xin; Zhou, Dao-Bin; Li, Jian

    2016-07-01

    POEMS syndrome is a rare plasma cell dyscrasia. Serum concentrations of the monoclonal protein in this disorder are typically low, and inapplicable to monitor disease activity in most cases, resulting in limited practical and prognostic values. Novel immunoassays measuring isotype-specific heavy/light chain (HLC) pairs showed its utility in disease monitoring and outcome prediction in several plasma cell dyscrasias. We report results of HLC measurements in 90 patients with POEMS syndrome. Sixty-six patients (73%; 95% confidence interval, 63-82%) had an abnormal HLC ratio at baseline. It could stratify the risk of disease relapse and was strongly associated with worse progression-free survival in a multivariate analysis (P = 0.021; hazard ratio [HR] 6.89, 95% CI 1.34-35.43). After therapy, HLC ratios improved, with 43 patients (48%) remaining abnormal. The post-therapeutic HLC ratio, if abnormal, also remained as an independent prognostic factor associated with worse progression-free survival (P = 0.019; HR 4.30, 95% CI 1.27-14.56). These results suggest the prognostic utility of HLC ratios in clinical management of POEMS patients. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  3. Integrated Risk Assessment to Natural Hazards in Motozintla, Chiapas, Mexico

    NASA Astrophysics Data System (ADS)

    Novelo-Casanova, D. A.

    2012-12-01

    An integrated risk assessment includes the analysis of all components of individual constituents of risk such as baseline study, hazard identification and categorization, hazard exposure, and vulnerability. Vulnerability refers to the inability of people, organizations, and societies to withstand adverse impacts from multiple stressors to which they are exposed. These impacts are due to characteristics inherent in social interactions, institutions, and systems of cultural values. Thus, social vulnerability is a pre-existing condition that affects a society's ability to prepare for and recover from a disruptive event. Risk is the probability of a loss, and this loss depends on three elements: hazard, exposure, and vulnerability. Thus, risk is the estimated impact that a hazard event would have on people, services, facilities, structures and assets in a community. In this work we assess the risk to natural hazards in the community of Motozintla located in southern Mexico in the state of Chiapas (15.37N, 92.25W) with a population of about 20 000 habitants. Due to its geographical and geological location, this community is continuously exposed to many different natural hazards (earthquakes, landslides, volcanic eruptions, and floods). To determine the level of exposure of the community to natural hazards, we developed integrated studies and analysis of seismic microzonation, landslide and flood susceptibility as well as volcanic impact using standard methodologies. Social vulnerability was quantified from data obtained from local families interviews. Five variables were considered: household structure quality and design, availability of basic public services, family economic conditions, existing family plans for disaster preparedness, and risk perception.The number of families surveyed was determined considering a sample statistically significant. The families that were interviewed were selected using the simple random sampling technique with replacement. With these

  4. Multi Hazard Assessment: The Azores Archipelagos (PT) case

    NASA Astrophysics Data System (ADS)

    Aifantopoulou, Dorothea; Boni, Giorgio; Cenci, Luca; Kaskara, Maria; Kontoes, Haris; Papoutsis, Ioannis; Paralikidis, Sideris; Psichogyiou, Christina; Solomos, Stavros; Squicciarino, Giuseppe; Tsouni, Alexia; Xerekakis, Themos

    2016-04-01

    The COPERNICUS EMS Risk & Recovery Mapping (RRM) activity offers services to support efficient design and implementation of mitigation measures and recovery planning based on EO data exploitation. The Azores Archipelagos case was realized in the context of the FWC 259811 Copernicus EMS RRM, and provides potential impact information for a number of natural disasters. The analysis identified population and assets at risk (infrastructures and environment). The risk assessment was based on hazard and vulnerability of structural elements, road network characteristics, etc. Integration of different hazards and risks was accounted in establishing the necessary first response/ first aid infrastructure. EO data (Pleiades and WV-2), were used to establish a detailed background information, common for the assessment of the whole of the risks. A qualitative Flood hazard level was established, through a "Flood Susceptibility Index" that accounts for upstream drainage area and local slope along the drainage network (Manfreda et al. 2014). Indicators, representing different vulnerability typologies, were accounted for. The risk was established through intersecting hazard and vulnerability (risk- specific lookup table). Probabilistic seismic hazards maps (PGA) were obtained by applying the Cornell (1968) methodology as implemented in CRISIS2007 (Ordaz et al. 2007). The approach relied on the identification of potential sources, the assessment of earthquake recurrence and magnitude distribution, the selection of ground motion model, and the mathematical model to calculate seismic hazard. Lava eruption areas and a volcanic activity related coefficient were established through available historical data. Lava flow paths and their convergence were estimated through applying a cellular, automata based, Lava Flow Hazard numerical model (Gestur Leó Gislason, 2013). The Landslide Hazard Index of NGI (Norwegian Geotechnical Institute) for heavy rainfall (100 year extreme monthly rainfall

  5. Hazardous-Materials Robot

    NASA Technical Reports Server (NTRS)

    Stone, Henry W.; Edmonds, Gary O.

    1995-01-01

    Remotely controlled mobile robot used to locate, characterize, identify, and eventually mitigate incidents involving hazardous-materials spills/releases. Possesses number of innovative features, allowing it to perform mission-critical functions such as opening and unlocking doors and sensing for hazardous materials. Provides safe means for locating and identifying spills and eliminates risks of injury associated with use of manned entry teams. Current version of vehicle, called HAZBOT III, also features unique mechanical and electrical design enabling vehicle to operate safely within combustible atmosphere.

  6. 46 CFR 151.03-30 - Hazardous material.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Hazardous material. 151.03-30 Section 151.03-30 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Definitions § 151.03-30 Hazardous material. In this part hazardous material means a liquid material or substance that is— (a) Flammable or combustible; (b...

  7. 46 CFR 151.03-30 - Hazardous material.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 5 2012-10-01 2012-10-01 false Hazardous material. 151.03-30 Section 151.03-30 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Definitions § 151.03-30 Hazardous material. In this part hazardous material means a liquid material or substance that is— (a) Flammable or combustible; (b...

  8. 46 CFR 151.03-30 - Hazardous material.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 5 2013-10-01 2013-10-01 false Hazardous material. 151.03-30 Section 151.03-30 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Definitions § 151.03-30 Hazardous material. In this part hazardous material means a liquid material or substance that is— (a) Flammable or combustible; (b...

  9. Quantifying asymmetry: ratios and alternatives.

    PubMed

    Franks, Erin M; Cabo, Luis L

    2014-08-01

    Traditionally, the study of metric skeletal asymmetry has relied largely on univariate analyses, utilizing ratio transformations when the goal is comparing asymmetries in skeletal elements or populations of dissimilar dimensions. Under this approach, raw asymmetries are divided by a size marker, such as a bilateral average, in an attempt to produce size-free asymmetry indices. Henceforth, this will be referred to as "controlling for size" (see Smith: Curr Anthropol 46 (2005) 249-273). Ratios obtained in this manner often require further transformations to interpret the meaning and sources of asymmetry. This model frequently ignores the fundamental assumption of ratios: the relationship between the variables entered in the ratio must be isometric. Violations of this assumption can obscure existing asymmetries and render spurious results. In this study, we examined the performance of the classic indices in detecting and portraying the asymmetry patterns in four human appendicular bones and explored potential methodological alternatives. Examination of the ratio model revealed that it does not fulfill its intended goals in the bones examined, as the numerator and denominator are independent in all cases. The ratios also introduced strong biases in the comparisons between different elements and variables, generating spurious asymmetry patterns. Multivariate analyses strongly suggest that any transformation to control for overall size or variable range must be conducted before, rather than after, calculating the asymmetries. A combination of exploratory multivariate techniques, such as Principal Components Analysis, and confirmatory linear methods, such as regression and analysis of covariance, appear as a promising and powerful alternative to the use of ratios. © 2014 Wiley Periodicals, Inc.

  10. Health concerns and hazardous waste

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Yassi, A.; Weeks, J.; Kraut, A.

    1990-01-01

    This report discusses health effects of hazardous waste and emphasizes human health concerns related to establishing a hazardous waste management facility. The study reviewed world epidemiological and public health literature to identify cases of suspected or substantiated claims of public health impacts associated with hazardous waste management facilities and potential products or emissions from such facilities, and placed them into perspective, including possible routes and consequences of exposure, risk assessment, and the toxicity of selected organic and inorganic compounds.

  11. 14 CFR 437.55 - Hazard analysis.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... 14 Aeronautics and Space 4 2013-01-01 2013-01-01 false Hazard analysis. 437.55 Section 437.55... TRANSPORTATION LICENSING EXPERIMENTAL PERMITS Safety Requirements § 437.55 Hazard analysis. (a) A permittee must... safety of property resulting from each permitted flight. This hazard analysis must— (1) Identify and...

  12. 14 CFR 437.55 - Hazard analysis.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... 14 Aeronautics and Space 4 2012-01-01 2012-01-01 false Hazard analysis. 437.55 Section 437.55... TRANSPORTATION LICENSING EXPERIMENTAL PERMITS Safety Requirements § 437.55 Hazard analysis. (a) A permittee must... safety of property resulting from each permitted flight. This hazard analysis must— (1) Identify and...

  13. BEHAVIORAL HAZARD IN HEALTH INSURANCE*

    PubMed Central

    Baicker, Katherine; Mullainathan, Sendhil; Schwartzstein, Joshua

    2015-01-01

    A fundamental implication of standard moral hazard models is overuse of low-value medical care because copays are lower than costs. In these models, the demand curve alone can be used to make welfare statements, a fact relied on by much empirical work. There is ample evidence, though, that people misuse care for a different reason: mistakes, or “behavioral hazard.” Much high-value care is underused even when patient costs are low, and some useless care is bought even when patients face the full cost. In the presence of behavioral hazard, welfare calculations using only the demand curve can be off by orders of magnitude or even be the wrong sign. We derive optimal copay formulas that incorporate both moral and behavioral hazard, providing a theoretical foundation for value-based insurance design and a way to interpret behavioral “nudges.” Once behavioral hazard is taken into account, health insurance can do more than just provide financial protection—it can also improve health care efficiency. PMID:23930294

  14. Ultrasonic dental scaler: associated hazards.

    PubMed

    Trenter, S C; Walmsley, A D

    2003-02-01

    The ultrasonic dental scaler is a valuable tool in the prevention of periodontal disease; however, this equipment has a number of hazards with which it is associated. These include heating of the tooth during scaling, vibrational hazards causing cell disruption, possible platelet damage by cavitation, associated electromagnetic fields that can interrupt pacemakers, auditory damage to patient and clinician and the release of aerosols containing dangerous bacteria. To collate the research reported on the various hazards associated with the ultrasonic dental scaler and discuss possible future research areas. The scientific literature was searched using Web of Science, EMBASE and Medline, and the results of these were then hand-searched to eliminate nonrelevant papers. This review outlines some of the research conducted into these areas of associated hazard in order to assess their significance in the clinical situation, and discusses ideas for future research. Suggestions of recommendations are given, which have been previously investigated for their aid in reducing possible hazards, to ensure the safe working of ultrasonic scalers in the dental practice.

  15. Quantitative estimation of time-variable earthquake hazard by using fuzzy set theory

    NASA Astrophysics Data System (ADS)

    Deyi, Feng; Ichikawa, M.

    1989-11-01

    In this paper, the various methods of fuzzy set theory, called fuzzy mathematics, have been applied to the quantitative estimation of the time-variable earthquake hazard. The results obtained consist of the following. (1) Quantitative estimation of the earthquake hazard on the basis of seismicity data. By using some methods of fuzzy mathematics, seismicity patterns before large earthquakes can be studied more clearly and more quantitatively, highly active periods in a given region and quiet periods of seismic activity before large earthquakes can be recognized, similarities in temporal variation of seismic activity and seismic gaps can be examined and, on the other hand, the time-variable earthquake hazard can be assessed directly on the basis of a series of statistical indices of seismicity. Two methods of fuzzy clustering analysis, the method of fuzzy similarity, and the direct method of fuzzy pattern recognition, have been studied is particular. One method of fuzzy clustering analysis is based on fuzzy netting, and another is based on the fuzzy equivalent relation. (2) Quantitative estimation of the earthquake hazard on the basis of observational data for different precursors. The direct method of fuzzy pattern recognition has been applied to research on earthquake precursors of different kinds. On the basis of the temporal and spatial characteristics of recognized precursors, earthquake hazards in different terms can be estimated. This paper mainly deals with medium-short-term precursors observed in Japan and China.

  16. Hazard avoidance via descent images for safe landing

    NASA Astrophysics Data System (ADS)

    Yan, Ruicheng; Cao, Zhiguo; Zhu, Lei; Fang, Zhiwen

    2013-10-01

    In planetary or lunar landing missions, hazard avoidance is critical for landing safety. Therefore, it is very important to correctly detect hazards and effectively find a safe landing area during the last stage of descent. In this paper, we propose a passive sensing based HDA (hazard detection and avoidance) approach via descent images to lower the landing risk. In hazard detection stage, a statistical probability model on the basis of the hazard similarity is adopted to evaluate the image and detect hazardous areas, so that a binary hazard image can be generated. Afterwards, a safety coefficient, which jointly utilized the proportion of hazards in the local region and the inside hazard distribution, is proposed to find potential regions with less hazards in the binary hazard image. By using the safety coefficient in a coarse-to-fine procedure and combining it with the local ISD (intensity standard deviation) measure, the safe landing area is determined. The algorithm is evaluated and verified with many simulated descent downward looking images rendered from lunar orbital satellite images.

  17. Household Hazardous Waste and Demolition

    EPA Pesticide Factsheets

    Household wastes that are toxic, corrosive, ignitable, or reactive are known as Household Hazardous Waste (HHW). Household Hazardous Waste may be found during residential demolitions, and thus require special handling for disposal.

  18. Composition and health hazards of water-based construction paints: results from a survey in the Netherlands.

    PubMed Central

    van Faassen, A; Borm, P J

    1991-01-01

    Water-based construction paints may have beneficial effects toward man's occupational and general environment when compared to traditional paints that contain large amounts of organic solvents. The aim of this study was to describe the health hazards of the application of these alternative paints. The composition of these paints was obtained by a questionnaire survey among the main producers and importers in The Netherlands. Physicochemical parameters and toxicity data of the constituents were used to estimate occupational and environmental health hazards. Mucous membrane of skin irritation and sensitization are predicted to be the most frequently occurring health hazards after contact with these paints during professional or do-it-yourself application. Health hazards from environmental pollution may be irritation of the mucous membranes when the indoor environment is painted and fish mortality due to slowly degradable polyacrylate binders. The health hazards can be reduced by replacing some toxic compounds with less toxic ones and by hygienic (ventilation, skincare, no cleaning of application materials under the tap) measures. PMID:1935844

  19. 49 CFR 173.2 - Hazardous materials classes and index to hazard class definitions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ....50 1 1.6 Extremely insensitive detonating substances 173.50 2 2.1 Flammable gas 173.115 2 2.2 Non-flammable compressed gas 173.115 2 2.3 Poisonous gas 173.115 3 Flammable and combustible liquid 173.120 4 4... PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS...

  20. 49 CFR 173.2 - Hazardous materials classes and index to hazard class definitions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ....50 1 1.6 Extremely insensitive detonating substances 173.50 2 2.1 Flammable gas 173.115 2 2.2 Non-flammable compressed gas 173.115 2 2.3 Poisonous gas 173.115 3 Flammable and combustible liquid 173.120 4 4... PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS...

  1. 49 CFR 173.2 - Hazardous materials classes and index to hazard class definitions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ....50 1 1.6 Extremely insensitive detonating substances 173.50 2 2.1 Flammable gas 173.115 2 2.2 Non-flammable compressed gas 173.115 2 2.3 Poisonous gas 173.115 3 Flammable and combustible liquid 173.120 4 4... PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS...

  2. 49 CFR 173.2 - Hazardous materials classes and index to hazard class definitions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ....50 1 1.6 Extremely insensitive detonating substances 173.50 2 2.1 Flammable gas 173.115 2 2.2 Non-flammable compressed gas 173.115 2 2.3 Poisonous gas 173.115 3 Flammable and combustible liquid 173.120 4 4... PIPELINE AND HAZARDOUS MATERIALS SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION HAZARDOUS MATERIALS...

  3. Thinking of Wildfire as a Natural Hazard

    Treesearch

    Sarah McCaffrey

    2004-01-01

    Natural hazards theory with its emphasis on understanding the human-hazard interaction has much to offer in better understanding how individuals respond to the wildfire hazard. Ironically, very few natural hazards studies have actually looked at wildfires, despite the insights the field might offer. This report is structured around four interrelated questions that are...

  4. RADIATION HAZARD

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Savenko, I.A.; Pisarenko, N.F.; Shavrin, P.I.

    1961-01-01

    Analysis of data obtained by Sputnik V (August 19, 1961) at about 320 km made it possible to delineate the position of the radiation belts and to estimate the amount of radiation hazard present. Scintillation counter data show that the radiation in the belts is anisotropic and that the energy flux under a layer of matter of 2 x 10/sup -3/ g cm/sup -2/ is 10/sup 10/ ev cm/sup -2/ sec/sup -1/. The mean energy released per quantum in the scintillation counter crystal is computed at 2.0 x 10/sup 5/ ev and the intensity of electrons in the outer beltmore » at 5 x 10/sup 4/ particles cm/sup -2/ sec/sup -1/. The radiation dosage absorbed inside Sputnik V was determined by dividing the amount of energy liberated in the sodium iodide crystal of the scinitillation counter by the weight of the crystal (36.4 g) without the need of a detailed examination of the composition and spectrum of the radiation. A dosage value of 7 mrad/24 hr was obtained; in terms of the RBE (relative biological effect) of the cosmic charged particles this amounted to 5O mrem/24 hr. This dosage is considered relatively safe for astronauts during flights along trajectories similar to that of Sputnik V when the sun is quiet. Solar flares, however, could bring about an increase in radiation. Owing to latitude and longitude effects and the specifi distribution of radiation at this height, the dosage per orbit ranged from 0.35 to 0.70 mrad. (OTS)« less

  5. Stable Carbon Isotope Ratios in Atmospheric VOC across the Asian Summer Monsoon Anticyclone obtained during the OMO-ASIA campaign

    NASA Astrophysics Data System (ADS)

    Krebsbach, Marc; Koppmann, Ralf; Meisehen, Thomas

    2017-04-01

    The automated high volume air sampling system (MIRAH) has been deployed during the atmospheric measurement campaign OMO-ASIA (Oxidation Mechanism Observations) with the German High Altitude - Long-range research aircraft (HALO) in July and August 2015. The intensive measurement period with base stations in Paphos (Cyprus) and Gan (Maldives) focussed on oxidation processes and air pollution chemistry downwind of the South Asia summer monsoon anticyclone, a pivot area critical for air quality and climate change, both regionally and worldwide. The measurement region covered the Eastern Mediterranean region, the Arabian Peninsula, Egypt, and the Arabian Sea. In total 194 air samples were collected on 17 flights in a height region from 3 km up to 15 km. The air samples were analysed for stable carbon isotope ratios in VOC with GC-C-IRMS in the laboratory afterwards. We determined stable carbon isotope ratios and mixing ratios of several aldehydes, ketones, alcohols, and aromatics. The large extent of the investigated area allowed for encountering air masses with different origin, characteristic, and atmospheric processing, e.g. Mediterranean air masses, crossing of polluted filaments and remnants of the Asian monsoon outflow, split of the Asian monsoon anticyclone. In this presentation we will show first results and interpretations supported by HYSPLIT backward trajectories.

  6. Federal Register Notice: State Authorization To Regulate the Hazardous Components of Radioactive Mixed Wastes Under the Resource Conservation and Recovery Act

    EPA Pesticide Factsheets

    The Environmental Protection Agency (EPA) is today publishing a notice that in order to obtain and maintain authorization to administer and enforce a hazardous waste program pursuant to Subtitle C of the Resource Conservation and Recovery Act (RCRA), States must have authority to regulate the hazardous components of 'radioactive mixed wastes.

  7. Estimating surface hardening profile of blank for obtaining high drawing ratio in deep drawing process using FE analysis

    NASA Astrophysics Data System (ADS)

    Tan, C. J.; Aslian, A.; Honarvar, B.; Puborlaksono, J.; Yau, Y. H.; Chong, W. T.

    2015-12-01

    We constructed an FE axisymmetric model to simulate the effect of partially hardened blanks on increasing the limiting drawing ratio (LDR) of cylindrical cups. We partitioned an arc-shaped hard layer into the cross section of a DP590 blank. We assumed the mechanical property of the layer is equivalent to either DP980 or DP780. We verified the accuracy of the model by comparing the calculated LDR for DP590 with the one reported in the literature. The LDR for the partially hardened blank increased from 2.11 to 2.50 with a 1 mm depth of DP980 ring-shaped hard layer on the top surface of the blank. The position of the layer changed with drawing ratios. We proposed equations for estimating the inner and outer diameters of the layer, and tested its accuracy in the simulation. Although the outer diameters fitted in well with the estimated line, the inner diameters are slightly less than the estimated ones.

  8. Prognostic value of the neutrophil to lymphocyte ratio in lung cancer: A meta-analysis.

    PubMed

    Yin, Yongmei; Wang, Jun; Wang, Xuedong; Gu, Lan; Pei, Hao; Kuai, Shougang; Zhang, Yingying; Shang, Zhongbo

    2015-07-01

    Recently, a series of studies explored the correlation between the neutrophil to lymphocyte ratio and the prognosis of lung cancer. However, the current opinion regarding the prognostic role of the neutrophil to lymphocyte ratio in lung cancer is inconsistent. We performed a meta-analysis of published articles to investigate the prognostic value of the neutrophil to lymphocyte ratio in lung cancer. The hazard ratio (HR) and its 95% confidence interval (CI) were calculated. An elevated neutrophil to lymphocyte ratio predicted worse overall survival, with a pooled HR of 1.243 (95%CI: 1.106-1.397; P(heterogeneity)=0.001) from multivariate studies and 1.867 (95%CI: 1.487-2.344; P(heterogeneity)=0.047) from univariate studies. Subgroup analysis showed that a high neutrophil to lymphocyte ratio yielded worse overall survival in non-small cell lung cancer (NSCLC) (HR=1.192, 95%CI: 1.061-1.399; P(heterogeneity)=0.003) as well as small cell lung cancer (SCLC) (HR=1.550, 95% CI: 1.156-2.077; P(heterogeneity)=0.625) in multivariate studies. The synthesized evidence from this meta-analysis of published articles demonstrated that an elevated neutrophil to lymphocyte ratio was a predictor of poor overall survival in patients with lung cancer.

  9. Hazardous waste management in the Pacific basin

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Cirillo, R.R.; Chiu, S.; Chun, K.C.

    1994-11-01

    Hazardous waste control activities in Asia and the Pacific have been reviewed. The review includes China (mainland, Hong Kong, and Taiwan), Indonesia, Korea, Malaysia, Papua New Guinea, the Philippines, Singapore, and Thailand. It covers the sources of hazardous waste, the government structure for dealing with hazardous waste, and current hazardous waste control activities in each country. In addition, the hazardous waste program activities of US government agencies, US private-sector organizations, and international organizations are reviewed. The objective of these reviews is to provide a comprehensive picture of the current hazardous waste problems and the waste management approaches being used tomore » address them so that new program activities can be designed more efficiently.« less

  10. High normal urine albumin-to-creatinine ratio predicts development of hypertension in Korean men.

    PubMed

    Park, Sung Keun; Moon, Soo Young; Oh, Chang-Mo; Ryoo, Jae-Hong; Park, Min Suk

    2014-01-01

    Microalbuminuria is known as a risk factor for hypertension. Recently it was suggested that urine albumin-to-creatinine ratio (UACR), even within the normal range, can be associated with hypertension, but the temporal relationship between normal range UACR and hypertension was not confirmed. Therefore the aim of this study was to verify an association between normal range UACR and the development of hypertension in Korean men. This prospective cohort study was performed on 1,284 initially non-hypertensive Korean men. The total follow-up period was 4,109.5 person-years and the mean follow-up period was 3.2±1.51 years. Cox proportional hazards model was used to estimate the hazard ratios (HR) for the risk of hypertension development. After adjusting for multiple covariates, the HR (95% confidence interval [CI]) for incident hypertension, comparing the second to the fourth quartiles of UACR level to the first quartile, were 1.35 (95% CI: 0.93-1.97), 1.55 (95% CI: 1.07-2.25) and 1.89 (95% CI: 1.31-2.71), respectively (P for trend=0.001). High UACR within the normal range was significantly associated with hypertension development. Furthermore, this association remained significant after adjusting for multiple baseline covariates. 

  11. Utilization of Zn-containing electric arc furnace dust for multi-metal doped ferrite with enhanced magnetic property: From hazardous solid waste to green product.

    PubMed

    Wang, Hui-Gang; Zhang, Mei; Guo, Min

    2017-10-05

    One-step solid state reaction method was proposed for the first time to realize the transformation of the Zn-containing EAFD from hazardous solid waste to multi-metal doped ferrite with enhanced magnetic property. The effect of Zn-containing EAFD to NiCl 2 ·6H 2 O mass ratio (R ZE/N , g·g -1 ) on the phases transformation was investigated by X-ray diffraction (XRD), Scanning electron microscopy (SEM) and Raman spectroscopy. The as-synthesized samples were treated by toxicity characteristic leaching procedure (TCLP). It is shown that the TCPL played a key role in determining both the purity and toxicity of the obtained ferrites. The pure metal doped Ni-Zn ferrite with higher saturation magnetization (Ms, 56.8 emu·g -1 ) and lower coercivity (Hc, 58.5Oe) was gained under the optimum conditions. And the pure ferrite was a green product according to the TCLP and EN12457 standards. Moreover, the evaluation of environmental impact and the recovery ratio of the dust were also discussed. Copyright © 2017. Published by Elsevier B.V.

  12. The situation of hazardous chemical accidents in China between 2000 and 2006.

    PubMed

    Duan, Weili; Chen, Guohua; Ye, Qing; Chen, Qingguang

    2011-02-28

    From the aspects of the total quantity of accidents, regional inequality, enterprises scale and environmental pollution accidents, this study makes an analysis of hazardous chemical accidents in China for the period spanning from 2000 to 2006. The following results are obtained: firstly, there were lots of accidents and fatalities in hazardous chemical business, i.e., the number of casualty accidents fluctuated between 200 and 600/year, the number of fatality fluctuated between 220 and 1100/year. Secondly, the accident rate in developed southeast coastal areas, e.g., Guangdong, Zhejiang and Jiangsu, was far higher than that in the northwest regions, e.g., Xizang, Xinjiang, and Qinghai. Thirdly, nearly 80% of dangerous chemical accidents had occurred in small and medium-sized enterprises (SMEs). Finally, various sudden environmental pollution accidents resulted from hazardous chemicals were frequent in recent years, causing a huge damage to human and property. Then, based on the readjustment of economic structure in the last decades, the development status of Occupational Health and Safety (OHS) in SMEs and other factors, the paper explores the main causes, which offers valuable insight into measures that should be taken to reduce hazardous chemical accidents. Copyright © 2010 Elsevier B.V. All rights reserved.

  13. Simulation program for estimating statistical power of Cox's proportional hazards model assuming no specific distribution for the survival time.

    PubMed

    Akazawa, K; Nakamura, T; Moriguchi, S; Shimada, M; Nose, Y

    1991-07-01

    Small sample properties of the maximum partial likelihood estimates for Cox's proportional hazards model depend on the sample size, the true values of regression coefficients, covariate structure, censoring pattern and possibly baseline hazard functions. Therefore, it would be difficult to construct a formula or table to calculate the exact power of a statistical test for the treatment effect in any specific clinical trial. The simulation program, written in SAS/IML, described in this paper uses Monte-Carlo methods to provide estimates of the exact power for Cox's proportional hazards model. For illustrative purposes, the program was applied to real data obtained from a clinical trial performed in Japan. Since the program does not assume any specific function for the baseline hazard, it is, in principle, applicable to any censored survival data as long as they follow Cox's proportional hazards model.

  14. Controlling organic chemical hazards in food manufacturing: a hazard analysis critical control points (HACCP) approach.

    PubMed

    Ropkins, K; Beck, A J

    2002-08-01

    Hazard analysis by critical control points (HACCP) is a systematic approach to the identification, assessment and control of hazards. Effective HACCP requires the consideration of all hazards, i.e., chemical, microbiological and physical. However, to-date most 'in-place' HACCP procedures have tended to focus on the control of microbiological and physical food hazards. In general, the chemical component of HACCP procedures is either ignored or limited to applied chemicals, e.g., food additives and pesticides. In this paper we discuss the application of HACCP to a broader range of chemical hazards, using organic chemical contaminants as examples, and the problems that are likely to arise in the food manufacturing sector. Chemical HACCP procedures are likely to result in many of the advantages previously identified for microbiological HACCP procedures: more effective, efficient and economical than conventional end-point-testing methods. However, the high costs of analytical monitoring of chemical contaminants and a limited understanding of formulation and process optimisation as means of controlling chemical contamination of foods are likely to prevent chemical HACCP becoming as effective as microbiological HACCP.

  15. Adjusted variable plots for Cox's proportional hazards regression model.

    PubMed

    Hall, C B; Zeger, S L; Bandeen-Roche, K J

    1996-01-01

    Adjusted variable plots are useful in linear regression for outlier detection and for qualitative evaluation of the fit of a model. In this paper, we extend adjusted variable plots to Cox's proportional hazards model for possibly censored survival data. We propose three different plots: a risk level adjusted variable (RLAV) plot in which each observation in each risk set appears, a subject level adjusted variable (SLAV) plot in which each subject is represented by one point, and an event level adjusted variable (ELAV) plot in which the entire risk set at each failure event is represented by a single point. The latter two plots are derived from the RLAV by combining multiple points. In each point, the regression coefficient and standard error from a Cox proportional hazards regression is obtained by a simple linear regression through the origin fit to the coordinates of the pictured points. The plots are illustrated with a reanalysis of a dataset of 65 patients with multiple myeloma.

  16. Characteristics of civil aviation atmospheric hazards

    NASA Technical Reports Server (NTRS)

    Marshall, Robert E.; Montoya, J.; Richards, Mark A.; Galliano, J.

    1994-01-01

    Clear air turbulence, wake vortices, dry hail, and volcanic ash are hazards to civil aviation that have not been brought to the forefront of public attention by a catastrophic accident. However, these four hazards are responsible for major and minor injuries, emotional trauma, significant aircraft damage, and in route and terminal area inefficiency. Most injuries occur during clear air turbulence. There is significant aircraft damage for any volcanic ash encounter. Rolls induced by wake vortices occur near the ground. Dry hail often appears as an area of weak echo on the weather radar. This paper will present the meteorological, electromagnetic, and spatiotemporal characteristics of each hazard. A description of a typical aircraft encounter with each hazard will be given. Analyzed microwave and millimeter wave sensor systems to detect each hazard will be presented.

  17. Potential primary and secondary hazards of avicides

    USGS Publications Warehouse

    Schafer, E.W.; Clark, Dell O.

    1984-01-01

    There are six chemicals or groups of chemicals that are currently registered as avicides that can be used in some or all of the U.S. Most of these chemicals, because of their diverse chemical composition and innate toxicological effects, present somewhat different primary and secondary hazards to avian and mammalian predators and scavengers. Of the chemicals reviewed, all appear to present some degree of primary hazard to non-target birds and mammals; however, PA-14, the Starlicide family of chemicals and fenthion appear to be the least hazardous when used according to use directions. 4-Aminopyridine, endrin and strychnine, because of their high acute toxicity and lack of selectivity, must be considered potentially more hazardous. With respect to secondary hazards, the ranking of chemicals changes considerably and only PA-14 appears to present a negligible hazard. The Starlicide family of chemicals presents negligible hazards to most animal species under currently registered uses, but may be potentially hazardous to cats and owls under specific use conditions. Two chemicals, 4-aminopyridine and strychnine, are potentially more hazardous to predatory and scavenger animals due to their highly toxic nature and rapid lethal effects in target species, leaving unassimilated chemical in the gastrointestinal tract. The remaining chemicals, endrin and fenthion, have been shown to possess the potential for more significant secondary poisoning; however, because of restrictive uses, most of the potential hazards have been avoided in operational use.

  18. Evaluation of neutrophil/leukocyte ratio and organ failure score as predictors of reversibility and survival following an acute-on-chronic liver failure event.

    PubMed

    Agiasotelli, Danai; Alexopoulou, Alexandra; Vasilieva, Larisa; Kalpakou, Georgia; Papadaki, Sotiria; Dourakis, Spyros P

    2016-05-01

    Acute-on-chronic liver failure (ACLF) is defined as an acute deterioration of liver disease with high mortality in patients with cirrhosis. The early mortality in ACLF is associated with organ failure and high leukocyte count. The time needed to reverse this condition and the factors affecting mortality after the early 30-day-period were evaluated. One hundred and ninety-seven consecutive patients with cirrhosis were included. Patients were prospectively followed up for 180 days. ACLF was diagnosed in 54.8% of the patients. Infection was the most common precipitating event in patients with ACLF. On multivariate analysis, only the neutrophil/leukocyte ratio and Chronic Liver Failure Consortium Organ Failure (CLIF-C OF) score were associated with mortality. Hazard ratios for mortality of patients with ACLF compared with those without at different time end-points post-enrollment revealed that the relative risk of death in the ACLF group was 8.54 during the first 30-day period and declined to 1.94 during the second period of observation. The time varying effect of neutrophil/leukocyte ratio and CLIF-C score was negative (1% and 18% decline in the hazard ratio per month) while that of Model for End-Stage Liver Disease (MELD) was positive (3% increase in the hazard ratio per month). The condition of ACLF was reversible in patients who survived. During the 30-180-day period following the acute event, the probability of death in ACLF became gradually similar to the non-ACLF group. The impact of inflammatory response and organ failure on survival is powerful during the first 30-day period and weakens thereafter while that of MELD increases. © 2015 The Japan Society of Hepatology.

  19. Swirl ratio effects on tornado-like vortices

    NASA Astrophysics Data System (ADS)

    Hashemi-Tari, Pooyan; Gurka, Roi; Hangen, Horia

    2007-11-01

    The effect of swirl ratio on the flow field for a tornado-like vortex simulator (TVS) is investigated. Different swirl ratios are obtained by changing the geometry and tangential velocity which determine the vortex evolution. Flow visualizations, surface pressure and Particle Image Velocimetry (PIV) measurements are performed in a small TVS for swirl ratios S between 0 and 1. The PIV data was acquired for two orthogonal planes: normal and parallel to the solid boundary at several height locations. The ratio between the angular momentum and the radial momentum which characterize the swirl ratio is investigated. Statistical analysis to the turbulent field is performed by mean and rms profiles of the velocity, stresses and vorticity are presented. A Proper Orthogonal Decomposition (POD) is performed on the vorticity field. The results are used to: (i) provide a relation between these 3 sets of qualitative and quantitative measurements and the swirl ratio in an attempt to relate the fluid dynamics parameters to the forensic, Fujita scale, and (ii) understand the spatio-temporal distribution of the most energetic POD modes in a tornado-like vortex.

  20. Food-safety hazards in the pork chain in Nagaland, North East India: implications for human health.

    PubMed

    Fahrion, Anna Sophie; Jamir, Lanu; Richa, Kenivole; Begum, Sonuwara; Rutsa, Vilatuo; Ao, Simon; Padmakumar, Varijaksha P; Deka, Ram Pratim; Grace, Delia

    2013-12-24

    Pork occupies an important place in the diet of the population of Nagaland, one of the North East Indian states. We carried out a pilot study along the pork meat production chain, from live animal to end consumer. The goal was to obtain information about the presence of selected food borne hazards in pork in order to assess the risk deriving from these hazards to the health of the local consumers and make recommendations for improving food safety. A secondary objective was to evaluate the utility of risk-based approaches to food safety in an informal food system. We investigated samples from pigs and pork sourced at slaughter in urban and rural environments, and at retail, to assess a selection of food-borne hazards. In addition, consumer exposure was characterized using information about hygiene and practices related to handling and preparing pork. A qualitative hazard characterization, exposure assessment and hazard characterization for three representative hazards or hazard proxies, namely Enterobacteriaceae, T. solium cysticercosis and antibiotic residues, is presented. Several important potential food-borne pathogens are reported for the first time including Listeria spp. and Brucella suis. This descriptive pilot study is the first risk-based assessment of food safety in Nagaland. We also characterise possible interventions to be addressed by policy makers, and supply data to inform future risk assessments.

  1. Correlates of household seismic hazard adjustment adoption.

    PubMed

    Lindell, M K; Whitney, D J

    2000-02-01

    This study examined the relationships of self-reported adoption of 12 seismic hazard adjustments (pre-impact actions to reduce danger to persons and property) with respondents' demographic characteristics, perceived risk, perceived hazard knowledge, perceived protection responsibility, and perceived attributes of the hazard adjustments. Consistent with theoretical predictions, perceived attributes of the hazard adjustments differentiated among the adjustments and had stronger correlations with adoption than any of the other predictors. These results identify the adjustments and attributes that emergency managers should address to have the greatest impact on improving household adjustment to earthquake hazard.

  2. Hazardous Waste: Cleanup and Prevention.

    ERIC Educational Resources Information Center

    Vandas, Steve; Cronin, Nancy L.

    1996-01-01

    Describes the Superfund, a federal cleanup program created in response to growing public concern over the health and environmental risks posed by hazardous waste sites. Discusses sources, disposal, and movement and risk of hazardous waste. (JRH)

  3. Development of vulnerability curves to typhoon hazards based on insurance policy and claim dataset

    NASA Astrophysics Data System (ADS)

    Mo, Wanmei; Fang, Weihua; li, Xinze; Wu, Peng; Tong, Xingwei

    2016-04-01

    Vulnerability refers to the characteristics and circumstances of an exposure that make it vulnerable to the effects of some certain hazards. It can be divided into physical vulnerability, social vulnerability, economic vulnerabilities and environmental vulnerability. Physical vulnerability indicates the potential physical damage of exposure caused by natural hazards. Vulnerability curves, quantifying the loss ratio against hazard intensity with a horizontal axis for the intensity and a vertical axis for the Mean Damage Ratio (MDR), is essential to the vulnerability assessment and quantitative evaluation of disasters. Fragility refers to the probability of diverse damage states under different hazard intensity, revealing a kind of characteristic of the exposure. Fragility curves are often used to quantify the probability of a given set of exposure at or exceeding a certain damage state. The development of quantitative fragility and vulnerability curves is the basis of catastrophe modeling. Generally, methods for quantitative fragility and vulnerability assessment can be categorized into empirical, analytical and expert opinion or judgment-based ones. Empirical method is one of the most popular methods and it relies heavily on the availability and quality of historical hazard and loss dataset, which has always been a great challenge. Analytical method is usually based on the engineering experiments and it is time-consuming and lacks built-in validation, so its credibility is also sometimes criticized widely. Expert opinion or judgment-based method is quite effective in the absence of data but the results could be too subjective so that the uncertainty is likely to be underestimated. In this study, we will present the fragility and vulnerability curves developed with empirical method based on simulated historical typhoon wind, rainfall and induced flood, and insurance policy and claim datasets of more than 100 historical typhoon events. Firstly, an insurance exposure

  4. Are Global Economic Losses from Natural Hazards Increasing?

    NASA Astrophysics Data System (ADS)

    McMullan, Caroline; Simic, Milan; Tosco, Antonello; Latchman, Shane

    2016-04-01

    Global society has long been influenced by natural hazards, but it has been widely noted that the economic cost of natural hazards has been rising rapidly over recent decades. This upward trend highlights the increasing exposure of the global economy to natural hazards and the need for society to understand the driving factors to help improve the resilience of communities. However disaster risk is driven by a plethora of factors, including population, wealth, land-use, and demographics. Consider also the natural variability in the frequency and severity of events, climate change, and implementation of resilience policies, and it becomes clear that disaster-risk management is a challenging field. To investigate the apparent upward trend in reported annual economic losses from natural disasters, socioeconomic factors known to influence the magnitude of losses must first be accounted for. Adjustment for these factors, known as loss normalisation, aims to estimate the losses sustained if historical events were to impact present day society. We have undertaken a detailed assessment of global economic losses from natural disasters for the period 1995 through 2013. Although the studied time-period is relatively short, expanding the investigated period would not necessarily produce more reliable insights owing to the inherent difficulty in obtaining accurate economic loss estimates for earlier periods and the challenge of finding consistent and reliable sources of socioeconomic data for the normalisation process. The results of the study, presented at a global and regional level, appear to suggest that the main driver of perceived increase in economic losses over the last ~20 years was the development of nations' economies (i.e. increase in population and wealth/GDP) and not in the natural hazards themselves. As populations all over the world migrate into areas of higher natural hazards regions (e.g. coastal areas or floodplain zones) and global wealth continues to

  5. Southern Dietary Pattern is Associated With Hazard of Acute Coronary Heart Disease in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study.

    PubMed

    Shikany, James M; Safford, Monika M; Newby, P K; Durant, Raegan W; Brown, Todd M; Judd, Suzanne E

    2015-09-01

    The association of overall diet, as characterized by dietary patterns, with risk of incident acute coronary heart disease (CHD) has not been studied extensively in samples including sociodemographic and regional diversity. We used data from 17 418 participants in Reasons for Geographic and Racial Differences in Stroke (REGARDS), a national, population-based, longitudinal study of white and black adults aged ≥45 years, enrolled from 2003 to 2007. We derived dietary patterns with factor analysis and used Cox proportional hazards regression to examine hazard of incident acute CHD events - nonfatal myocardial infarction and acute CHD death - associated with quartiles of consumption of each pattern, adjusted for various levels of covariates. Five primary dietary patterns emerged: Convenience, Plant-based, Sweets, Southern, and Alcohol and Salad. A total of 536 acute CHD events occurred over a median (interquartile range) 5.8 (2.1) years of follow-up. After adjustment for sociodemographics, lifestyle factors, and energy intake, highest consumers of the Southern pattern (characterized by added fats, fried food, eggs, organ and processed meats, and sugar-sweetened beverages) experienced a 56% higher hazard of acute CHD (comparing quartile 4 with quartile 1: hazard ratio, 1.56; 95% confidence interval, 1.17-2.08; P for trend across quartiles=0.003). Adding anthropometric and medical history variables to the model attenuated the association somewhat (hazard ratio, 1.37; 95% confidence interval, 1.01-1.85; P=0.036). A dietary pattern characteristic of the southern United States was associated with greater hazard of CHD in this sample of white and black adults in diverse regions of the United States. © 2015 American Heart Association, Inc.

  6. Urban Heat Wave Hazard Assessment

    NASA Astrophysics Data System (ADS)

    Quattrochi, D. A.; Jedlovec, G.; Crane, D. L.; Meyer, P. J.; LaFontaine, F.

    2016-12-01

    Heat waves are one of the largest causes of environmentally-related deaths globally and are likely to become more numerous as a result of climate change. The intensification of heat waves by the urban heat island effect and elevated humidity, combined with urban demographics, are key elements leading to these disasters. Better warning of the potential hazards may help lower risks associated with heat waves. Moderate resolution thermal data from NASA satellites is used to derive high spatial resolution estimates of apparent temperature (heat index) over urban regions. These data, combined with demographic data, are used to produce a daily heat hazard/risk map for selected cities. MODIS data are used to derive daily composite maximum and minimum land surface temperature (LST) fields to represent the amplitude of the diurnal temperature cycle and identify extreme heat days. Compositing routines are used to generate representative daily maximum and minimum LSTs for the urban environment. The limited effect of relative humidity on the apparent temperature (typically 10-15%) allows for the use of modeled moisture fields to convert LST to apparent temperature without loss of spatial variability. The daily max/min apparent temperature fields are used to identify abnormally extreme heat days relative to climatological values in order to produce a heat wave hazard map. Reference to climatological values normalizes the hazard for a particular region (e.g., the impact of an extreme heat day). A heat wave hazard map has been produced for several case study periods and then computed on a quasi-operational basis during the summer of 2016 for Atlanta, GA, Chicago, IL, St. Louis, MO, and Huntsville, AL. A hazard does not become a risk until someone or something is exposed to that hazard at a level that might do harm. Demographic information is used to assess the urban risk associated with the heat wave hazard. Collectively, the heat wave hazard product can warn people in urban

  7. Aortic Cross-Sectional Area/Height Ratio and Outcomes in Patients With a Trileaflet Aortic Valve and a Dilated Aorta.

    PubMed

    Masri, Ahmad; Kalahasti, Vidyasagar; Svensson, Lars G; Roselli, Eric E; Johnston, Douglas; Hammer, Donald; Schoenhagen, Paul; Griffin, Brian P; Desai, Milind Y

    2016-11-29

    In patients with a dilated proximal ascending aorta and trileaflet aortic valve, we aimed to assess (1) factors independently associated with increased long-term mortality and (2) the incremental prognostic utility of indexing aortic root to patient height. We studied consecutive patients with a dilated aortic root (≥4 cm) that underwent echocardiography and gated contrast-enhanced thoracic aortic computed tomography or magnetic resonance angiography between 2003 and 2007. A ratio of aortic root area over height was calculated (cm 2 /m) on tomography, and a cutoff of 10 cm 2 /m was chosen as abnormal, on the basis of previous reports. All-cause death was recorded. The cohort comprised 771 patients (63 years [interquartile range, 53-71], 87% men, 85% hypertension, 51% hyperlipidemia, 56% smokers). Inherited aortopathies, moderate to severe aortic regurgitation, and severe aortic stenosis were seen in 7%, 18%, and 2%, whereas 91% and 54% were on β-blockers and angiotensin-converting enzyme inhibitors, respectively. Aortic root area/height ratio was ≥10 cm 2 /m in 24%. The Society of Thoracic Surgeons score and right ventricular systolic pressure were 3.3±3 and 31±7 mm Hg, respectively. At 7.8 years (interquartile range, 6.6-8.9), 280 (36%) patients underwent aortic surgery (76% within 1 year) and 130 (17%) died (1% in-hospital postoperative mortality). A lower proportion of patients in the surgical (versus nonsurgical) group died (13% versus 19%, P<0.01). On multivariable Cox proportional hazard analysis, aortic root area/height ratio (hazard ratio, 4.04; 95% confidence interval [CI], 2.69-6.231) was associated with death, whereas aortic surgery (hazard ratio, 0.47; 95% CI, 0.27-0.81) was associated with improved survival (both P<0.01). For longer-term mortality, the addition of aortic root area/height ratio ≥10 cm 2 /m to a clinical model (Society of Thoracic Surgeons score, inherited aortopathies, hypertension, hyperlipidemia, medications, aortic

  8. Probabilistic analysis of tsunami hazards

    USGS Publications Warehouse

    Geist, E.L.; Parsons, T.

    2006-01-01

    Determining the likelihood of a disaster is a key component of any comprehensive hazard assessment. This is particularly true for tsunamis, even though most tsunami hazard assessments have in the past relied on scenario or deterministic type models. We discuss probabilistic tsunami hazard analysis (PTHA) from the standpoint of integrating computational methods with empirical analysis of past tsunami runup. PTHA is derived from probabilistic seismic hazard analysis (PSHA), with the main difference being that PTHA must account for far-field sources. The computational methods rely on numerical tsunami propagation models rather than empirical attenuation relationships as in PSHA in determining ground motions. Because a number of source parameters affect local tsunami runup height, PTHA can become complex and computationally intensive. Empirical analysis can function in one of two ways, depending on the length and completeness of the tsunami catalog. For site-specific studies where there is sufficient tsunami runup data available, hazard curves can primarily be derived from empirical analysis, with computational methods used to highlight deficiencies in the tsunami catalog. For region-wide analyses and sites where there are little to no tsunami data, a computationally based method such as Monte Carlo simulation is the primary method to establish tsunami hazards. Two case studies that describe how computational and empirical methods can be integrated are presented for Acapulco, Mexico (site-specific) and the U.S. Pacific Northwest coastline (region-wide analysis).

  9. 21 CFR 123.6 - Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... identified food safety hazards, including as appropriate: (i) Critical control points designed to control... control points designed to control food safety hazards introduced outside the processing plant environment... Control Point (HACCP) plan. 123.6 Section 123.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF...

  10. 21 CFR 123.6 - Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... identified food safety hazards, including as appropriate: (i) Critical control points designed to control... control points designed to control food safety hazards introduced outside the processing plant environment... Control Point (HACCP) plan. 123.6 Section 123.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF...

  11. 21 CFR 123.6 - Hazard analysis and Hazard Analysis Critical Control Point (HACCP) plan.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... identified food safety hazards, including as appropriate: (i) Critical control points designed to control... control points designed to control food safety hazards introduced outside the processing plant environment... Control Point (HACCP) plan. 123.6 Section 123.6 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF...

  12. The rockfall hazard rating system.

    DOT National Transportation Integrated Search

    1991-11-01

    The development and dissemination of the Rockfall Hazard Rating System (RHRS) is complete. RHRS is intended to be a proactive tool that will allow transportation agencies to address rationally their rockfall hazards instead of simply reacting to rock...

  13. Analytical investigation of different mathematical approaches utilizing manipulation of ratio spectra

    NASA Astrophysics Data System (ADS)

    Osman, Essam Eldin A.

    2018-01-01

    This work represents a comparative study of different approaches of manipulating ratio spectra, applied on a binary mixture of ciprofloxacin HCl and dexamethasone sodium phosphate co-formulated as ear drops. The proposed new spectrophotometric methods are: ratio difference spectrophotometric method (RDSM), amplitude center method (ACM), first derivative of the ratio spectra (1DD) and mean centering of ratio spectra (MCR). The proposed methods were checked using laboratory-prepared mixtures and were successfully applied for the analysis of pharmaceutical formulation containing the cited drugs. The proposed methods were validated according to the ICH guidelines. A comparative study was conducted between those methods regarding simplicity, limitations and sensitivity. The obtained results were statistically compared with those obtained from the reported HPLC method, showing no significant difference with respect to accuracy and precision.

  14. Occupational hazards to health of port workers.

    PubMed

    Wang, Yukun; Zhan, Shuifen; Liu, Yan; Li, Yan

    2017-12-01

    The aim of this article is to reduce the risk of occupational hazards and improve safety conditions by enhancing hazard knowledge and identification as well as improving safety behavior for freight port enterprises. In the article, occupational hazards to health and their prevention measures of freight port enterprises have been summarized through a lot of occupational health evaluation work, experience and understanding. Workers of freight port enterprises confront an equally wide variety of chemical, physical and psychological hazards in production technology, production environment and the course of labor. Such health hazards have been identified, the risks evaluated, the dangers to health notified and effective prevention measures which should be put in place to ensure the health of the port workers summarized. There is still a long way to go for the freight port enterprises to prevent and control the occupational hazards. Except for occupational hazards and their prevention measures, other factors that influence the health of port workers should also be paid attention to, such as age, work history, gender, contraindication and even the occurrence and development rules of occupational hazards in current production conditions.

  15. Seismic Hazard and Ground Motion Characterization at the Itoiz Dam (Northern Spain)

    NASA Astrophysics Data System (ADS)

    Rivas-Medina, A.; Santoyo, M. A.; Luzón, F.; Benito, B.; Gaspar-Escribano, J. M.; García-Jerez, A.

    2012-08-01

    This paper presents a new hazard-consistent ground motion characterization of the Itoiz dam site, located in Northern Spain. Firstly, we propose a methodology with different approximation levels to the expected ground motion at the dam site. Secondly, we apply this methodology taking into account the particular characteristics of the site and of the dam. Hazard calculations were performed following the Probabilistic Seismic Hazard Assessment method using a logic tree, which accounts for different seismic source zonings and different ground-motion attenuation relationships. The study was done in terms of peak ground acceleration and several spectral accelerations of periods coinciding with the fundamental vibration periods of the dam. In order to estimate these ground motions we consider two different dam conditions: when the dam is empty ( T = 0.1 s) and when it is filled with water to its maximum capacity ( T = 0.22 s). Additionally, seismic hazard analysis is done for two return periods: 975 years, related to the project earthquake, and 4,975 years, identified with an extreme event. Soil conditions were also taken into account at the site of the dam. Through the proposed methodology we deal with different forms of characterizing ground motion at the study site. In a first step, we obtain the uniform hazard response spectra for the two return periods. In a second step, a disaggregation analysis is done in order to obtain the controlling earthquakes that can affect the dam. Subsequently, we characterize the ground motion at the dam site in terms of specific response spectra for target motions defined by the expected values SA ( T) of T = 0.1 and 0.22 s for the return periods of 975 and 4,975 years, respectively. Finally, synthetic acceleration time histories for earthquake events matching the controlling parameters are generated using the discrete wave-number method and subsequently analyzed. Because of the short relative distances between the controlling

  16. Hydrogen Hazards Assessment Protocol (HHAP): Approach and Methodology

    NASA Technical Reports Server (NTRS)

    Woods, Stephen

    2009-01-01

    This viewgraph presentation reviews the approach and methodology to develop a assessment protocol for hydrogen hazards. Included in the presentation are the reasons to perform hazards assessment, the types of hazard assessments that exist, an analysis of hydrogen hazards, specific information about the Hydrogen Hazards Assessment Protocol (HHAP). The assessment is specifically tailored for hydrogen behavior. The end product of the assesment is a compilation of hazard, mitigations and associated factors to facilitate decision making and achieve the best practice.

  17. Natural radioactivity and radiation hazards in some building materials used in Isparta, Turkey

    NASA Astrophysics Data System (ADS)

    Mavi, B.; Akkurt, I.

    2010-09-01

    The activity concentrations of uranium, thorium and potassium can vary from material to material and it should be measured as the radiation is hazardous for human health. Thus first studies have been planned to obtain radioactivity of building material used in the Isparta region of Turkey. The radioactivity of some building materials used in this region has been measured using a γ-ray spectrometry, which contains a NaI(Tl) detector connected to MCA. The specific activity for 226Ra, 232Th and 40K, from the selected building materials, were in the range 17.91-58.88, 6.77-19.49 and 65.72-248.76 Bq/kg, respectively. Absorbed dose rate in air ( D), annual effective dose (AED), radium equivalent activities (Ra eq), and external hazard index ( Hex) associated with the natural radionuclide are calculated to assess the radiation hazard of the natural radioactivity in the building materials. It was found that none of the results exceeds the recommended limit value.

  18. Natural Hazards - A National Threat

    USGS Publications Warehouse

    Geological Survey, U.S.

    2007-01-01

    The USGS Role in Reducing Disaster Losses -- In the United States each year, natural hazards cause hundreds of deaths and cost billions of dollars in disaster aid, disruption of commerce, and destruction of homes and critical infrastructure. Although the number of lives lost to natural hazards each year generally has declined, the economic cost of major disaster response and recovery continues to rise. Each decade, property damage from natural hazards events doubles or triples. The United States is second only to Japan in economic damages resulting from natural disasters. A major goal of the U.S. Geological Survey (USGS) is to reduce the vulnerability of the people and areas most at risk from natural hazards. Working with partners throughout all sectors of society, the USGS provides information, products, and knowledge to help build more resilient communities.

  19. A Sensor-Independent Gust Hazard Metric

    NASA Technical Reports Server (NTRS)

    Stewart, Eric C.

    2001-01-01

    A procedure for calculating an intuitive hazard metric for gust effects on airplanes is described. The hazard metric is for use by pilots and is intended to replace subjective pilot reports (PIREPs) of the turbulence level. The hazard metric is composed of three numbers: the first describes the average airplane response to the turbulence, the second describes the positive peak airplane response to the gusts, and the third describes the negative peak airplane response to the gusts. The hazard metric is derived from any time history of vertical gust measurements and is thus independent of the sensor making the gust measurements. The metric is demonstrated for one simulated airplane encountering different types of gusts including those derived from flight data recorder measurements of actual accidents. The simulated airplane responses to the gusts compare favorably with the hazard metric.

  20. National Practice Patterns of Obtaining Informed Consent for Stroke Thrombolysis.

    PubMed

    Mendelson, Scott J; Courtney, D Mark; Gordon, Elisa J; Thomas, Leena F; Holl, Jane L; Prabhakaran, Shyam

    2018-03-01

    No standard approach to obtaining informed consent for stroke thrombolysis with tPA (tissue-type plasminogen activator) currently exists. We aimed to assess current nationwide practice patterns of obtaining informed consent for tPA. An online survey was developed and distributed by e-mail to clinicians involved in acute stroke care. Multivariable logistic regression analyses were performed to determine independent factors contributing to always obtaining informed consent for tPA. Among 268 respondents, 36.7% reported always obtaining informed consent and 51.8% reported the informed consent process caused treatment delays. Being an emergency medicine physician (odds ratio, 5.8; 95% confidence interval, 2.9-11.5) and practicing at a nonacademic medical center (odds ratio, 2.1; 95% confidence interval, 1.0-4.3) were independently associated with always requiring informed consent. The most commonly cited cause of delay was waiting for a patient's family to reach consensus about treatment. Most clinicians always or often require informed consent for stroke thrombolysis. Future research should focus on standardizing content and delivery of tPA information to reduce delays. © 2018 American Heart Association, Inc.

  1. Laser-induced fluorescence ratios of Cajanus cajan L. under the stress of cadmium and its correlation with pigment content and pigment ratios.

    PubMed

    Maurya, Renu; Gopal, R

    2008-04-01

    Laser-induced fluorescence spectra were used to characterize the effect of cadmium on the pigment status of the leaves of Cajanus cajan L. Laser-induced fluorescence spectra of untreated as well as cadmium treated (0.01 mM, 0.10 mM, and 1.00 mM) Cajanus cajan L. were recorded using the 355 nm line of a Nd:YAG laser as the excitation source and a monochromator with an intensified charge-coupled device as a detector in the region 400-800 nm. The fluorescence intensity ratios (FIR) of control as well as treated Cajanus cajan L. have been calculated by evaluating curve fitted parameters using a Gaussian spectral function. In addition, some growth parameters, such as photosynthetic pigment content, were also measured. The 355 nm line of the laser-light-excited leaves not only showed a fluorescence emission in the red spectral region (650-800 nm), but also in the blue-green region (400-570 nm). The chlorophyll FIR F690/F740 strongly correlated with the photosynthetic pigment content (total chlorophyll and carotenoids) and its ratio. Consequently, a correlation was also seen between the ratio of the blue-green fluorescence F470/F540 and the photosynthetic pigment content. The results indicated that the plants treated with 0.01 mM of cadmium exhibited better growth, while higher concentrations of cadmium were hazardous for Cajanus cajan L.

  2. HAZARDOUS SUBSTANCES DATA BANK (HSDB)

    EPA Science Inventory

    Hazardous Substances Data Bank (HSDB) is a factual, non-bibliographic data bank focusing upon the toxicology of potentially hazardous chemicals. It is enhanced with data from such related areas as emergency handling procedures, environmental fate, human exposure, detection method...

  3. Model uncertainties of the 2002 update of California seismic hazard maps

    USGS Publications Warehouse

    Cao, T.; Petersen, M.D.; Frankel, A.D.

    2005-01-01

    In this article we present and explore the source and ground-motion model uncertainty and parametric sensitivity for the 2002 update of the California probabilistic seismic hazard maps. Our approach is to implement a Monte Carlo simulation that allows for independent sampling from fault to fault in each simulation. The source-distance dependent characteristics of the uncertainty maps of seismic hazard are explained by the fundamental uncertainty patterns from four basic test cases, in which the uncertainties from one-fault and two-fault systems are studied in detail. The California coefficient of variation (COV, ratio of the standard deviation to the mean) map for peak ground acceleration (10% of exceedance in 50 years) shows lower values (0.1-0.15) along the San Andreas fault system and other class A faults than along class B faults (0.2-0.3). High COV values (0.4-0.6) are found around the Garlock, Anacapa-Dume, and Palos Verdes faults in southern California and around the Maacama fault and Cascadia subduction zone in northern California.

  4. The efficacy of a brief intervention in reducing hazardous drinking in working age men in Russia: the HIM (Health for Izhevsk men) individually randomised parallel group exploratory trial

    PubMed Central

    2011-01-01

    intention to treat analyses. The unadjusted odds ratio (95% CI) for the effect of MI on hazardous and harmful drinking was 0.77 (0.51, 1.16). An adjusted odds ratio of 0.52 (0.28, 0.94) was obtained in the pre-specified per protocol analysis. Conclusions This trial demonstrates that it is possible to engage Russian men who drink hazardously in a brief intervention aimed at reducing alcohol related harm. However the results with respect to the efficacy are equivocal and further, larger-scale trials are warranted. Trial Registration ISRCTN: ISRCTN82405938 PMID:22053775

  5. Phytoremediation of Hazardous Wastes

    DTIC Science & Technology

    1995-07-26

    TITLE AND SUBTITLE Phytoremediation of Hazardous Wastes 6. AUTHOR(S) Steven C. McCutcheon, N. Lee Wolfe, Laura H. Carreria and Tse-Yuan Ou 5... phytoremediation (the use of plants to degrade hazardous contaminants) was developed. The new approach to phytoremediation involves rigorous pathway analyses...SUBJECT TERMS phytoremediation , nitroreductase, laccase enzymes, SERDP 15. NUMBER OF PAGES 8 16. PRICE CODE N/A 17. SECURITY CLASSIFICATION OF

  6. K Basin Hazard Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    PECH, S.H.

    This report describes the methodology used in conducting the K Basins Hazard Analysis, which provides the foundation for the K Basins Final Safety Analysis Report. This hazard analysis was performed in accordance with guidance provided by DOE-STD-3009-94, Preparation Guide for U. S. Department of Energy Nonreactor Nuclear Facility Safety Analysis Reports and implements the requirements of DOE Order 5480.23, Nuclear Safety Analysis Report.

  7. SCADA data and the quantification of hazardous events for QMRA.

    PubMed

    Nilsson, P; Roser, D; Thorwaldsdotter, R; Petterson, S; Davies, C; Signor, R; Bergstedt, O; Ashbolt, N

    2007-01-01

    The objective of this study was to assess the use of on-line monitoring to support the QMRA at water treatment plants studied in the EU MicroRisk project. SCADA data were obtained from three Catchment-to-Tap Systems (CTS) along with system descriptions, diary records, grab sample data and deviation reports. Particular attention was paid to estimating hazardous event frequency, duration and magnitude. Using Shewart and CUSUM we identified 'change-points' corresponding to events of between 10 min and >1 month duration in timeseries data. Our analysis confirmed it is possible to quantify hazardous event durations from turbidity, chlorine residual and pH records and distinguish them from non-hazardous variability in the timeseries dataset. The durations of most 'events' were short-term (0.5-2.3 h). These data were combined with QMRA to estimate pathogen infection risk arising from such events as chlorination failure. While analysis of SCADA data alone could identify events provisionally, its interpretation was severely constrained in the absence of diary records and other system information. SCADA data analysis should only complement traditional water sampling, rather than replace it. More work on on-line data management, quality control and interpretation is needed before it can be used routinely for event characterization.

  8. Airborne characterization of smoke marker ratios from prescribed burning

    NASA Astrophysics Data System (ADS)

    Sullivan, A. P.; May, A. A.; Lee, T.; McMeeking, G. R.; Kreidenweis, S. M.; Akagi, S. K.; Yokelson, R. J.; Urbanski, S. P.; Collett, J. L., Jr.

    2014-05-01

    A Particle-into-Liquid Sampler - Total Organic Carbon and fraction collector system was flown aboard aTwin Otter aircraft sampling prescribed burning emissions in South Carolina in November2011 to obtain smoke marker measurements. The fraction collector provided 2 min time-integrated off-line samples for carbohydrate (i.e., smoke markers levoglucosan, mannosan, galactosan) analysis by high-performance anion-exchange chromatography with pulsed amperometric detection. Each fire location appeared to have aunique Δ levoglucosan / Δ water-soluble organic carbon (WSOC) ratio (RF01/RF02/RF03/RF05 = 0.163 ± 0.007 μg C μg C-1, RF08 = 0.115 ± 0.011 μg C μg C-1, RF09A = 0.072 ± 0.028 μg C μg C-1, RF09B = 0.042 ± 0.008 μg C μg C-1). These ratios were comparable to those obtained from controlled laboratory burns and suggested that the emissions sampled during RF01/RF02/RF03/RF05 were dominated by the burning of grasses, RF08 by leaves, RF09A by needles, and RF09B by marsh grasses. These findings were further supported by the Δ galactosan / Δ levoglucosan ratios (RF01/RF02/RF03/RF05 = 0.067 ± 0.004 μg μg-1, RF08 = 0.085 ± 0.009 μg μg-1, RF09A = 0.101 ± 0.029 μg μg-1) obtained as well as by the ground-based fuel and filter sample analyses during RF01/RF02/RF03/RF05. Differences between Δ potassium / Δ levoglucosan ratios obtained for these prescribed fires vs. laboratory-scale measurements suggest that some laboratory burns may not accurately represent potassium emissions from prescribed burns. The Δ levoglucosan / Δ WSOC ratio had no clear dependence on smoke age or fire dynamics suggesting that this ratio is more dependent on the type of fuel being burned. Levoglucosan was stable over a timescale of at least 1.5 h and could be useful to help estimate the air quality impacts of biomass burning.

  9. Airborne characterization of smoke marker ratios from prescribed burning

    NASA Astrophysics Data System (ADS)

    Sullivan, A. P.; May, A. A.; Lee, T.; McMeeking, G. R.; Kreidenweis, S. M.; Akagi, S. K.; Yokelson, R. J.; Urbanski, S. P.; Collett, J. L., Jr.

    2014-10-01

    A Particle-Into-Liquid Sampler - Total Organic Carbon (PILS-TOC) and fraction collector system was flown aboard a Twin Otter aircraft sampling prescribed burning emissions in South Carolina in November 2011 to obtain smoke marker measurements. The fraction collector provided 2 min time-integrated offline samples for carbohydrate (i.e., smoke markers levoglucosan, mannosan, and galactosan) analysis by high-performance anion-exchange chromatography with pulsed amperometric detection. Each fire location appeared to have a unique Δlevoglucosan/Δwater-soluble organic carbon (WSOC) ratio (RF01/RF02/RF03/RF05 = 0.163 ± 0.007 μg C μg-1 C, RF08 = 0.115 ± 0.011 μg C μg-1 C, RF09A = 0.072 ± 0.028 μg C μg-1 C, and RF09B = 0.042 ± 0.008 μg C μg-1 C, where RF means research flight). These ratios were comparable to those obtained from controlled laboratory burns and suggested that the emissions sampled during RF01/F02/RF03/RF05 were dominated by the burning of grasses, RF08 by leaves, RF09A by needles, and RF09B by marsh grasses. These findings were further supported by the Δgalactosan/Δlevoglucosan ratios (RF01/RF02/RF03/RF05 = 0.067 ± 0.004 μg μg-1, RF08 = 0.085 ± 0.009 μg μg-1, and RF09A = 0.101 ± 0.029 μg μg-1) obtained as well as by the ground-based fuel and filter sample analyses during RF01/RF02/RF03/RF05. Differences between Δpotassium/Δlevoglucosan ratios obtained for these prescribed fires vs. laboratory-scale measurements suggest that some laboratory burns may not accurately represent potassium emissions from prescribed burns. The Δlevoglucosan/ΔWSOC ratio had no clear dependence on smoke age or fire dynamics suggesting that this ratio is more dependent on the type of fuel being burned. Levoglucosan was stable over a timescale of at least 1.5 h and could be useful to help estimate the air quality impacts of biomass burning.

  10. Geological hazard monitoring system in Georgia

    NASA Astrophysics Data System (ADS)

    Gaprindashvili, George

    2017-04-01

    Georgia belongs to one of world's most complex mountainous regions according to the scale and frequency of Geological processes and damage caused to population, farmlands, and Infrastructure facilities. Geological hazards (landslide, debrisflow/mudflow, rockfall, erosion and etc.) are affecting many populated areas, agricultural fields, roads, oil and gas pipes, high-voltage electric power transmission towers, hydraulic structures, and tourist complexes. Landslides occur almost in all geomorphological zones, resulting in wide differentiation in the failure types and mechanisms and in the size-frequency distribution. In Georgia, geological hazards triggered by: 1. Activation of highly intense earthquakes; 2. Meteorological events provoking the disaster processes on the background of global climatic change; 3. Large-scale Human impact on the environment. The prediction and monitoring of Geological Hazards is a very wide theme, which involves different researchers from different spheres. Geological hazard monitoring is essential to prevent and mitigate these hazards. In past years in Georgia several monitoring system, such as Ground-based geodetic techniques, Debrisflow Early Warning System (EWS) were installed on high sensitive landslide and debrisflow areas. This work presents description of Geological hazard monitoring system in Georgia.

  11. Sensing Hazards with Operational Unmanned Technology

    NASA Astrophysics Data System (ADS)

    Hood, R. E.

    2016-12-01

    The Unmanned Aircraft Systems (UAS) Program of the National Oceanic and Atmospheric Administration (NOAA) is working with the National Weather Service, the National Ocean Service, other Federal agencies, private industry, and academia to evaluate the feasibility of UAS observations to provide time critical information needed for situational awareness, prediction, warning, and damage assessment of hazards. This activity is managed within a portfolio of projects entitled "Sensing Hazards with Operational Unmanned Technology (SHOUT)." The diversity of this portfolio includes evaluations of high altitude UAS observations for high impact oceanic storms prediction to low altitude UAS observations of rivers, severe storms, and coastal areas for pre-hazard situational awareness and post-hazard damage assessments. Each SHOUT evaluation project begins with a proof-of-concept field demonstration of a UAS observing strategy for a given hazard and then matures to joint studies of both scientific data impact along with cost and operational feasibility of the observing strategy for routine applications. The technology readiness and preliminary evaulation results will be presented for several UAS observing strategies designed for improved observations of oceanic storms, floods, severe storms, and coastal ecosystem hazards.

  12. The Cox proportional Hazard model on duration of birth process

    NASA Astrophysics Data System (ADS)

    Wuryandari, Triastuti; Haryatmi Kartiko, Sri; Danardono

    2018-05-01

    The duration of birth process, which is measured from the birth sign until baby born, is one important factor to the whole outcome of delivery process. There is a method of birth process that given relaxing and gentle treatment to the mother caled as gentlebirth. Gentlebirth is a method of birth process that combines brain science, birth science and technology to empower positive birth without pain. However the effect of method to the duration of birth process is still need empirical investigations. Therefore, the objective of this paper is to analyze the duration of birth process using the appropriate statistical methods for durational data, survival data or time to event data. Since there are many variables or factor that may affect the duration, a regression model is considerated. The flexibility of the Cox Proportional Hazard Model in the sense that there is no distributional assumption required, makes the Cox Model as the appropriate model and method to analyze the duration birth process. It is concluded that the Gentlebirth method affects on duration of birth process, with Hazard Ratio of 2.073, showing that the duration of birth process with gentlebirth method is faster than the other method.

  13. J-SHIS - an integrated system for knowing seismic hazard information in Japan

    NASA Astrophysics Data System (ADS)

    Azuma, H.; Fujiwara, H.; Kawai, S.; Hao, K. X.; Morikawa, N.

    2015-12-01

    An integrated system of Japan seismic hazard information station (J-SHIS) was established in 2005 for issuing and exchanging information of the National Seismic Hazard Maps for Japan that are based on seismic hazard assessment (SHA). A simplified app, also named J-SHIS, for smartphones is popularly used in Japan based on the integrated system of http://www.j-shis.bosai.go.jp/map/?lang=en. "Smartphone tells hazard" is realized on a cellphone, a tablet and/or a PC. At a given spot, the comprehensive information of SHA map can be easily obtained as below: 1) A SHA probability at given intensity (JMA=5-, 5+, 6-, 6+) within 30 years. 2) A site amplification factor varies within 0.5 ~ 3.0 and expectation is 1 based on surface geology map information. 3) A depth of seismic basement down to ~3,000m based on deeper borehole and geological structure. 4) Scenario earthquake maps: By choosing an active fault, one got the average case for different parameters of the modeling. Then choose a case, you got the shaking map of intensity with color scale. "Seismic Hazard Karte tells more hazard" is another app based on website of http://www.j-shis.bosai.go.jp/labs/karte/. (1) For every mesh of 250m x 250m, professional service SHA information is provided over national-world. (2) With five ranks for eight items, comprehensive SHA information could be delivered. (3) Site amplification factor with an average index is given. (4) Deeper geologic structure modeling is provided with borehole profiling. (5) A SHA probability is assessed within 30 and/or 50 years for the given site. (6) Seismic Hazard curves are given for earthquake sources from inland active fault, subduction zone, undetermined and their summarization. (7) The JMA seismic intensities are assessed in long-term averaged periods of 500-years to ~100,000 years. The app of J-SHIS can be downloaded freely from http://www.j-shis.bosai.go.jp/app-jshis.

  14. Workplace hazards to women's reproductive health.

    PubMed

    Rice, Heidi Roeber; Baker, Beth A

    2007-09-01

    Women make up nearly half of Minnesota's workforce. Thus, many women, including those of reproductive age, are exposed to workplace hazards. These hazards may be chemical-toxicants such as heavy metals, pesticides, and endocrine disruptors; physical--the result of activities or proximity to something in the environment; or biological-infectious agents. And they are of growing concern among scientists and the public. Although data on the effect of these hazards on the reproductive health of women is limited, there is evidence indicating they ought to be of concern to women and the physicians who treat them. Clinicians are encouraged to assess women for exposure to workplace hazards and to communicate with them about whether such exposure might increase their risk for problems such as infertility, miscarriage, and preterm birth. This article highlights selected job-related hazards and offers suggestions for caring for working women of reproductive age.

  15. Laboratory Safety and Chemical Hazards.

    ERIC Educational Resources Information Center

    Journal of Chemical Education, 1983

    1983-01-01

    Toxicology/chemical hazards, safety policy, legal responsibilities, adequacy of ventilation, chemical storage, evaluating experimental hazards, waste disposal, and laws governing chemical safety were among topics discussed in 10 papers presented at the Seventh Biennial Conference on Chemical Education (Stillwater, Oklahoma 1982). Several topics…

  16. Hazardous Materials Flow by Rail

    DOT National Transportation Integrated Search

    1990-03-01

    The report presents a quantitative overview of the movement of hazardous materials by rail in the United States. The data used is a hazardous materials rail waybill sample developed at TSC from the 1983 Rail Waybill Sample. The report examines (1) th...

  17. Environmental Hazards Education for Childbirth Educators

    PubMed Central

    Ondeck, Michele; Focareta, Judith

    2009-01-01

    The purpose of this article is to educate childbirth educators about environmental hazards and provide resources. Hazardous chemicals have been found in cord blood, placenta, meconium, and breastmilk samples. These chemicals include commonly known hazards such as lead, mercury, and environmental tobacco smoke, as well as some pesticides, solvents, products containing chlorine, and other chemicals referred to as “persistent organic pollutants.” The fetus is particularly vulnerable to environmental chemicals that can disrupt the developmental process at critical times during gestation. Childbirth educators are encouraged to inform themselves in order to inform childbearing families to take preventive action and explore alternative behaviors to reduce exposure to environmental hazards. PMID:20808430

  18. Health and Ecological Hazards Caused by Hazardous Substances

    EPA Pesticide Factsheets

    In some cases, hazardous substances may irritate the skin or eyes, make it difficult to breathe, cause headaches and nausea, result in other types of illness, or far more severe health effects. Toxic effects on the environment can be just as devastating.

  19. TRENDS IN MORTALITY FROM OCCUPATIONAL HAZARDS AMONG MEN IN ENGLAND AND WALES DURING 1979-2010

    PubMed Central

    Harris, E Clare; Palmer, Keith T; Cox, Vanessa; Darnton, Andrew; Osman, John; Coggon, David

    2016-01-01

    Objectives To monitor the impact of health and safety provisions and inform future preventive strategies, we investigated trends in mortality from established occupational hazards in England and Wales. Methods We analysed data from death certificates on underlying cause of death and last full-time occupation for 3,688,916 deaths among men aged 20-74 years in England and Wales during 1979-2010 (excluding 1981 when records were incomplete). Proportional mortality ratios (PMRs), standardised for age and social class, were calculated for occupations at risk of specified hazards. Observed and expected numbers of deaths for each hazard were summed across occupations, and the differences summarised as average annual excesses. Results Excess mortality declined substantially for most hazards. For example, the annual excess of deaths from chronic bronchitis and emphysema fell from 170.7 during 1979-90 to 36.0 in 2001-10, and that for deaths from injury and poisoning from 237.0 to 87.5. In many cases the improvements were associated with falling PMRs (suggesting safer working practices), but they also reflected reductions in the numbers of men employed in more hazardous jobs, and declining mortality from some diseases across the whole population. Notable exceptions to the general improvement were diseases caused by asbestos, especially in some construction trades and sinonasal cancer in woodworkers. Conclusions The highest priority for future prevention of work-related fatalities is the minority of occupational disorders for which excess mortality remains static or is increasing, in particular asbestos-related disease among certain occupations in the construction industry and sinonasal cancer in woodworkers. PMID:26976946

  20. Recent advances to obtain real - Time displacements for engineering applications

    USGS Publications Warehouse

    Celebi, M.

    2005-01-01

    This paper presents recent developments and approaches (using GPS technology and real-time double-integration) to obtain displacements and, in turn, drift ratios, in real-time or near real-time to meet the needs of the engineering and user community in seismic monitoring and assessing the functionality and damage condition of structures. Drift ratios computed in near real-time allow technical assessment of the damage condition of a building. Relevant parameters, such as the type of connections and story structural characteristics (including geometry) are used in computing drifts corresponding to several pre-selected threshold stages of damage. Thus, drift ratios determined from real-time monitoring can be compared to pre-computed threshold drift ratios. The approaches described herein can be used for performance evaluation of structures and can be considered as building health-monitoring applications.

  1. The Impact of the Crown-Root Ratio on Survival of Abutment Teeth for Dentures.

    PubMed

    Tada, S; Allen, P F; Ikebe, K; Zheng, H; Shintani, A; Maeda, Y

    2015-09-01

    Crown-root ratio (CRR) is commonly recorded when planning prosthodontic procedures. However, there is a lack of longitudinal clinical data evaluating the association between CRR and tooth survival. The aim of this longitudinal practice-based study was to assess the impact of CRR on the survival of abutment teeth for removable partial dentures (RPDs). Data were collected from 147 patients provided with RPDs at a dental hospital in Japan. In total, 236 clasp-retained RPDs and 856 abutment teeth were analyzed. Survival of abutment teeth was assessed using Kaplan-Meier methods and Cox's proportional hazard (PH) regression. The Cox PH regression was used to assess the prognostic significance of initial CRR value with adjustments for clinically relevant factors, including age, sex, frequency of periodontal maintenance programs, occlusal support area, type of abutment tooth, status of endodontic treatment, and probing pocket depth. Abutment teeth were divided into 1 of 5 risk groups according to CRR: A (≤0.75), B (0.76-1.00), C (1.01-1.25), D (1.26-1.50) and E (≥1.51). The 7-year survival rate was 89.1% for group A, 85.9% for group B, 86.5% for group C, 76.9% for group D, and 46.7% for group E. The survival curves of groups A, B, and C were illustrated to be quite similar and favorable. The multivariable analysis treating CRR as a continuous variable allowed estimation of the hazard ratio at any specific CRR value. When CRR = 0.80 was set as a reference, the estimated hazard ratio was 0.58 for CRR = 0.50 (95% confidence interval [CI], 0.36-0.91), 1.13 for CRR = 1.00 (95% CI, 0.93-1.37), 1.35 for CRR = 1.25 (95% CI, 1.02-1.80), 1.53 for CRR = 1.50 (95% CI, 1.15-2.08), or 1.95 for CRR = 2.00 (95% CI, 1.44-2.65). These practice-based longitudinal data provide information to improve the evidence-based prognosis of teeth in providing prosthodontic procedures. © International & American Associations for Dental Research.

  2. Hazard assessment for small torrent catchments - lessons learned

    NASA Astrophysics Data System (ADS)

    Eisl, Julia; Huebl, Johannes

    2013-04-01

    The documentation of extreme events as a part of the integral risk management cycle is an important basis for the analysis and assessment of natural hazards. In July 2011 a flood event occurred in the Wölzer-valley in the province of Styria, Austria. For this event at the "Wölzerbach" a detailed event documentation was carried out, gathering data about rainfall, runoff and sediment transport as well as information on damaged objects, infrastructure or crops using various sources. The flood was triggered by heavy rainfalls in two tributaries of the Wölzer-river. Though a rain as well as a discharge gaging station exists for the Wölzer-river, the torrents affected by the high intensity rainfalls are ungaged. For these ungaged torrent catchments the common methods for hazard assessment were evaluated. The back-calculation of the rainfall event was done using a new approach for precipitation analysis. In torrent catchments especially small-scale and high-intensity rainfall events are mainly responsible for extreme events. Austria's weather surveillance radar is operated by the air traffic service "AustroControl". The usually available dataset is interpreted and shows divergences especially when it comes to high intensity rainfalls. For this study the raw data of the radar were requested and analysed. Further on the event was back-calculated with different rainfall-runoff models, hydraulic models and sediment transport models to obtain calibration parameters for future use in hazard assessment for this region. Since there are often problems with woody debris different scenarios were simulated. The calibrated and plausible results from the runoff models were used for the comparison with empirical approaches used in the practical sector. For the planning of mitigation measures of the Schöttl-torrent, which is one of the affected tributaries of the Wölzer-river, a physical scale model was used in addition to the insights of the event analysis to design a check dam

  3. A more powerful test based on ratio distribution for retention noninferiority hypothesis.

    PubMed

    Deng, Ling; Chen, Gang

    2013-03-11

    Rothmann et al. ( 2003 ) proposed a method for the statistical inference of fraction retention noninferiority (NI) hypothesis. A fraction retention hypothesis is defined as a ratio of the new treatment effect verse the control effect in the context of a time to event endpoint. One of the major concerns using this method in the design of an NI trial is that with a limited sample size, the power of the study is usually very low. This makes an NI trial not applicable particularly when using time to event endpoint. To improve power, Wang et al. ( 2006 ) proposed a ratio test based on asymptotic normality theory. Under a strong assumption (equal variance of the NI test statistic under null and alternative hypotheses), the sample size using Wang's test was much smaller than that using Rothmann's test. However, in practice, the assumption of equal variance is generally questionable for an NI trial design. This assumption is removed in the ratio test proposed in this article, which is derived directly from a Cauchy-like ratio distribution. In addition, using this method, the fundamental assumption used in Rothmann's test, that the observed control effect is always positive, that is, the observed hazard ratio for placebo over the control is greater than 1, is no longer necessary. Without assuming equal variance under null and alternative hypotheses, the sample size required for an NI trial can be significantly reduced if using the proposed ratio test for a fraction retention NI hypothesis.

  4. Tsunami hazard map in eastern Bali

    NASA Astrophysics Data System (ADS)

    Afif, Haunan; Cipta, Athanasius

    2015-04-01

    Bali is a popular tourist destination both for Indonesian and foreign visitors. However, Bali is located close to the collision zone between the Indo-Australian Plate and Eurasian Plate in the south and back-arc thrust off the northern coast of Bali resulted Bali prone to earthquake and tsunami. Tsunami hazard map is needed for better understanding of hazard level in a particular area and tsunami modeling is one of the most reliable techniques to produce hazard map. Tsunami modeling conducted using TUNAMI N2 and set for two tsunami sources scenarios which are subduction zone in the south of Bali and back thrust in the north of Bali. Tsunami hazard zone is divided into 3 zones, the first is a high hazard zones with inundation height of more than 3m. The second is a moderate hazard zone with inundation height 1 to 3m and the third is a low tsunami hazard zones with tsunami inundation heights less than 1m. Those 2 scenarios showed southern region has a greater potential of tsunami impact than the northern areas. This is obviously shown in the distribution of the inundated area in the south of Bali including the island of Nusa Penida, Nusa Lembongan and Nusa Ceningan is wider than in the northern coast of Bali although the northern region of the Nusa Penida Island more inundated due to the coastal topography.

  5. Tsunami hazard map in eastern Bali

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Afif, Haunan, E-mail: afif@vsi.esdm.go.id; Cipta, Athanasius; Australian National University, Canberra

    Bali is a popular tourist destination both for Indonesian and foreign visitors. However, Bali is located close to the collision zone between the Indo-Australian Plate and Eurasian Plate in the south and back-arc thrust off the northern coast of Bali resulted Bali prone to earthquake and tsunami. Tsunami hazard map is needed for better understanding of hazard level in a particular area and tsunami modeling is one of the most reliable techniques to produce hazard map. Tsunami modeling conducted using TUNAMI N2 and set for two tsunami sources scenarios which are subduction zone in the south of Bali and backmore » thrust in the north of Bali. Tsunami hazard zone is divided into 3 zones, the first is a high hazard zones with inundation height of more than 3m. The second is a moderate hazard zone with inundation height 1 to 3m and the third is a low tsunami hazard zones with tsunami inundation heights less than 1m. Those 2 scenarios showed southern region has a greater potential of tsunami impact than the northern areas. This is obviously shown in the distribution of the inundated area in the south of Bali including the island of Nusa Penida, Nusa Lembongan and Nusa Ceningan is wider than in the northern coast of Bali although the northern region of the Nusa Penida Island more inundated due to the coastal topography.« less

  6. Fixed-ratio discrimination: effects of response-produced blackouts1

    PubMed Central

    Lydersen, Tore; Crossman, E. K.

    1974-01-01

    For three pigeons, reinforcement depended upon a left side-key response after execution of a fixed ratio 10 on the center key, and upon a right side-key response after fixed ratio 20. Each response during the fixed ratios produced a 0.5-sec blackout. The time between the first and last response in fixed ratio 10 was then equated with the time between the first and last response in fixed ratio 20 by increasing the blackout duration. The accuracy of side-key choice was disrupted, thereby suggesting that time, rather than number of responses, controlled choice responding. When the time between the first and last response was equated during both ratios, asymptotic accuracy was approximately equal to (two birds) or somewhat higher than (one bird) that obtained previously. The results of probes with intermediate fixed ratios and blackouts suggested that control of side-key choice had transferred from the time between the first and last response in ratios to blackout duration. PMID:16811819

  7. 78 FR 45938 - Final Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-07-30

    ...] Final Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Final notice. SUMMARY: Flood hazard determinations, which may include additions or modifications of Base Flood Elevations (BFEs), base flood depths, Special Flood Hazard Area (SFHA) boundaries or zone designations, or...

  8. Identifying Hazards

    EPA Pesticide Factsheets

    The federal government has established a system of labeling hazardous materials to help identify the type of material and threat posed. Summaries of information on over 300 chemicals are maintained in the Envirofacts Master Chemical Integrator.

  9. Welfare state regimes and gender inequalities in the exposure to work-related psychosocial hazards.

    PubMed

    Campos-Serna, Javier; Ronda-Pérez, Elena; Moen, Bente E; Artazcoz, Lucia; Benavides, Fernando G

    2013-01-01

    Gender inequalities in the exposure to work-related psychosocial hazards are well established. However, little is known about how welfare state regimes influence these inequalities. To examine the relationship between welfare state regimes and gender inequalities in the exposure to work-related psychosocial hazards in Europe, considering occupational social class. We used a sample of 27, 465 workers from 28 European countries. Dependent variables were high strain, iso-strain, and effort-reward imbalance, and the independent was gender. We calculated the prevalence and prevalence ratio separately for each welfare state regime and occupational social class, using multivariate logistic regression models. More female than male managers/professionals were exposed to: high strain, iso-strain, and effort-reward imbalance in Scandinavian [adjusted prevalence ratio (aPR) = 2·26; 95% confidence interval (95% CI): 1·87-2·75; 2·12: 1·72-2·61; 1·41: 1·15-1·74; respectively] and Continental regimes (1·43: 1·23-1·54; 1·51: 1·23-1·84; 1·40: 1·17-1·67); and to high strain and iso-strain in Anglo-Saxon (1·92: 1·40-2·63; 1·85: 1·30-2·64; respectively), Southern (1·43: 1·14-1·79; 1·60: 1·18-2·18), and Eastern regimes (1·56: 1·35-1·81; 1·53: 1·28-1·83). Gender inequalities in the exposure to work-related psychosocial hazards were not lower in those welfare state regimes with higher levels of universal social protection policies.

  10. Isotopic Ratio, Isotonic Ratio, Isobaric Ratio and Shannon Information Uncertainty

    NASA Astrophysics Data System (ADS)

    Ma, Chun-Wang; Wei, Hui-Ling

    2014-11-01

    The isoscaling and the isobaric yield ratio difference (IBD) probes, both of which are constructed by yield ratio of fragment, provide cancelation of parameters. The information entropy theory is introduced to explain the physical meaning of the isoscaling and IBD probes. The similarity between the isoscaling and IBD results is found, i.e., the information uncertainty determined by the IBD method equals to β - α determined by the isoscaling (α (β) is the parameter fitted from the isotopic (isotonic) yield ratio).

  11. 29 CFR 1917.23 - Hazardous atmospheres and substances (see also § 1917.2 Hazardous cargo, material, substance or...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 29 Labor 7 2014-07-01 2014-07-01 false Hazardous atmospheres and substances (see also § 1917.2 Hazardous cargo, material, substance or atmosphere). 1917.23 Section 1917.23 Labor Regulations Relating to... TERMINALS Marine Terminal Operations § 1917.23 Hazardous atmospheres and substances (see also § 1917.2...

  12. 29 CFR 1917.23 - Hazardous atmospheres and substances (see also § 1917.2 Hazardous cargo, material, substance or...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 29 Labor 7 2012-07-01 2012-07-01 false Hazardous atmospheres and substances (see also § 1917.2 Hazardous cargo, material, substance or atmosphere). 1917.23 Section 1917.23 Labor Regulations Relating to... TERMINALS Marine Terminal Operations § 1917.23 Hazardous atmospheres and substances (see also § 1917.2...

  13. 29 CFR 1917.23 - Hazardous atmospheres and substances (see also § 1917.2 Hazardous cargo, material, substance or...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 29 Labor 7 2013-07-01 2013-07-01 false Hazardous atmospheres and substances (see also § 1917.2 Hazardous cargo, material, substance or atmosphere). 1917.23 Section 1917.23 Labor Regulations Relating to... TERMINALS Marine Terminal Operations § 1917.23 Hazardous atmospheres and substances (see also § 1917.2...

  14. 29 CFR 1917.23 - Hazardous atmospheres and substances (see also § 1917.2 Hazardous cargo, material, substance or...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 29 Labor 7 2011-07-01 2011-07-01 false Hazardous atmospheres and substances (see also § 1917.2 Hazardous cargo, material, substance or atmosphere). 1917.23 Section 1917.23 Labor Regulations Relating to... TERMINALS Marine Terminal Operations § 1917.23 Hazardous atmospheres and substances (see also § 1917.2...

  15. A methodology for physically based rockfall hazard assessment

    NASA Astrophysics Data System (ADS)

    Crosta, G. B.; Agliardi, F.

    Rockfall hazard assessment is not simple to achieve in practice and sound, physically based assessment methodologies are still missing. The mobility of rockfalls implies a more difficult hazard definition with respect to other slope instabilities with minimal runout. Rockfall hazard assessment involves complex definitions for "occurrence probability" and "intensity". This paper is an attempt to evaluate rockfall hazard using the results of 3-D numerical modelling on a topography described by a DEM. Maps portraying the maximum frequency of passages, velocity and height of blocks at each model cell, are easily combined in a GIS in order to produce physically based rockfall hazard maps. Different methods are suggested and discussed for rockfall hazard mapping at a regional and local scale both along linear features or within exposed areas. An objective approach based on three-dimensional matrixes providing both a positional "Rockfall Hazard Index" and a "Rockfall Hazard Vector" is presented. The opportunity of combining different parameters in the 3-D matrixes has been evaluated to better express the relative increase in hazard. Furthermore, the sensitivity of the hazard index with respect to the included variables and their combinations is preliminarily discussed in order to constrain as objective as possible assessment criteria.

  16. Volcanic hazards on the Island of Hawaii

    USGS Publications Warehouse

    Mullineaux, Donal Ray; Peterson, Donald W.

    1974-01-01

    Volcanic hazards on the Island of Hawaii have been determined to be chiefly products of eruptions: lava flows, falling fragments, gases, and particle-and-gas clouds. Falling fragments and particle-and-gas clouds can be substantial hazards to life, but they are relatively rare. Lava flows are the chief hazard to property; they are frequent and cover broad areas. Rupture, subsidence, earthquakes, and sea waves (tsunamis) caused by eruptions are minor hazards; those same events caused by large-scale crustal movements, however, are major hazards to both life and property. Volcanic hazards are greatest on Mauna Loa and Kilauea, and the risk is highest along the rift zones of those volcanoes. The hazards are progressively less severe on Hualalai, Mauna Kea, and Kohala volcanoes. Some risk from earthquakes extends across the entire island, and the risk from tsunamis is high all along the coast. The island has been divided into geographic zones of different relative risk for each volcanic hazard, and for all those hazards combined. Each zone is assigned a relative risk for that area as a whole; the degree of risk varies within the zones, however, and in some of them the risk decreases gradationally across the entire zone. Moreover, the risk in one zone may be locally as great or greater than that at some points in the zone of next higher overall risk. Nevertheless, the zones can be highly useful for land-use planning. Planning decisions to which the report is particularly applicable include the selection of kinds of structures and kinds of land use that are appropriate for the severity and types of hazards present. For example, construction of buildings that can resist a lava flow is generally not feasible, but it is both feasible and desirable to build structures that can resist falling rock fragments, earthquakes, and tsunamis in areas where risk from those hazards is relatively high. The report can also be used to select sites where overall risk is relatively low, to

  17. Hazardous Materials Hazard Analysis, Portland, Oregon.

    DTIC Science & Technology

    1981-06-01

    combustible liquids, primarily petroleum products such as gasoline and fuel oil . Although less prevalent, compressed flammable gases (such as liquid...magnitude when hazardous materials are involved. -- Texas City, Texas, 1947--A ship being loaded with ammonium nitrate exploded, killing 468 people...An overturned gasoline or home heating fuel oil tanker or natural gas leak which does not ignite would be a Level 1 emergency. Level 2: A spill or

  18. Seismic hazard in the Intermountain West

    USGS Publications Warehouse

    Haller, Kathleen; Moschetti, Morgan P.; Mueller, Charles; Rezaeian, Sanaz; Petersen, Mark D.; Zeng, Yuehua

    2015-01-01

    The 2014 national seismic-hazard model for the conterminous United States incorporates new scientific results and important model adjustments. The current model includes updates to the historical catalog, which is spatially smoothed using both fixed-length and adaptive-length smoothing kernels. Fault-source characterization improved by adding faults, revising rates of activity, and incorporating new results from combined inversions of geologic and geodetic data. The update also includes a new suite of published ground motion models. Changes in probabilistic ground motion are generally less than 10% in most of the Intermountain West compared to the prior assessment, and ground-motion hazard in four Intermountain West cities illustrates the range and magnitude of change in the region. Seismic hazard at reference sites in Boise and Reno increased as much as 10%, whereas hazard in Salt Lake City decreased 5–6%. The largest change was in Las Vegas, where hazard increased 32–35%.

  19. EVA Hazards due to TPS Inspection and Repair

    NASA Technical Reports Server (NTRS)

    Stewart, Christine E.

    2007-01-01

    Tile inspection and repair activities have implicit hazards associated with them. When an Extra Vehicular Activities (EVA) crewmember and associated hardware are added into the equation, additional hazards are introduced. Potential hazards to the Extravehicular Mobility Unit (EMU), the Orbiter or the crew member themselves are created. In order to accurately assess the risk of performing a TPS inspection or repair, an accurate evaluation of potential hazards and how adequately these hazards are controlled is essential. The EMU could become damaged due to sharp edges, protrusions, thermal extremes, molten metal or impact with the Orbiter. Tools, tethers and the presence of a crew member in the vicinity of the Orbiter Thermal Protection System (TPS) pose hazards to the Orbiter. Hazards such as additional tile or Reinforced Carbon-Carbon (RCC) damage from a loose tool, safety tethers, crewmember or arm impact are introduced. Additionally, there are hazards to the crew which should be addressed. Crew hazards include laser injury, electrical shock, inability to return to the airlock for EMU failures or Orbiter rapid safing scenarios, as well as the potential inadvertent release of a crew member from the arm/boom. The aforementioned hazards are controlled in various ways. Generally, these controls are addressed operationally versus by design, as the majority of the interfaces are to the Orbiter and the Orbiter design did not originally account for tile repair. The Shuttle Remote Manipulator System (SRMS), for instance, was originally designed to deploy experiments, and therefore has insufficient design controls for retention of the Orbiter Boom Sensor System (OBSS). Although multiple methods to repair the Orbiter TPS exist, the majority of the hazards are applicable no matter which specific repair method is being performed. TPS Inspection performed via EVA also presents some of the same hazards. Therefore, the hazards common to all TPS inspection or repair methods will

  20. Hazard ranking systems for chemical wastes and chemical waste sites. Hazardous waste ranking systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Waters, R.D.; Parker, F.L.; Crutcher, M.R.

    Hazardous materials and substances have always existed in the environment. Mankind has evolved to live with some degree of exposure to toxic materials. Until recently the risk has been from natural toxins or natural background radiation. While rapid technological advances over the past few decades have improved the lifestyle of our society, they have also dramatically increased the availability, volume and types of synthetic and natural hazardous materials. Many of their effects are as yet uncertain. Products and manufacturing by-products that no longer serve a useful purpose are deemed wastes. For some waste products land disposal will always be theirmore » ultimate fate. Hazardous substances are often included in the waste products. One needs to classify wastes by degree of hazard (risk). Risk (degree of probability of loss) is usually defined for risk assessment as probability of an occurrence times the consequences of the occurrence. Perhaps even more important than the definition of risk is the choice of a risk management strategy. The choice of strategy will be strongly influenced by the decision criteria used. Those decision criteria could be utility (the greatest happiness of the greatest number), rights or technology based or some combination of the three. It is necessary to make such choices about the definition of risks and criteria for management. It is clear that these are social (i.e., political) and value choices and science has little to say on this matter. This is another example of what Alvin Weinberg has named Transcience where the subject matter is scientific and technical but the choices are social, political and moral. This paper shall deal only with the scientific and technical aspects of the hazardous waste problem to create a hazardous substances classification system.« less

  1. Linking rainfall-induced landslides with debris flows runout patterns towards catchment scale hazard assessment

    NASA Astrophysics Data System (ADS)

    Fan, Linfeng; Lehmann, Peter; McArdell, Brian; Or, Dani

    2017-03-01

    Debris flows and landslides induced by heavy rainfall represent an ubiquitous and destructive natural hazard in steep mountainous regions. For debris flows initiated by shallow landslides, the prediction of the resulting pathways and associated hazard is often hindered by uncertainty in determining initiation locations, volumes and mechanical state of the mobilized debris (and by model parameterization). We propose a framework for linking a simplified physically-based debris flow runout model with a novel Landslide Hydro-mechanical Triggering (LHT) model to obtain a coupled landslide-debris flow susceptibility and hazard assessment. We first compared the simplified debris flow model of Perla (1980) with a state-of-the art continuum-based model (RAMMS) and with an empirical model of Rickenmann (1999) at the catchment scale. The results indicate that predicted runout distances by the Perla model are in reasonable agreement with inventory measurements and with the other models. Predictions of localized shallow landslides by LHT model provides information on water content of released mass. To incorporate effects of water content and flow viscosity as provided by LHT on debris flow runout, we adapted the Perla model. The proposed integral link between landslide triggering susceptibility quantified by LHT and subsequent debris flow runout hazard calculation using the adapted Perla model provides a spatially and temporally resolved framework for real-time hazard assessment at the catchment scale or along critical infrastructure (roads, railroad lines).

  2. 78 FR 14584 - Proposed Flood Hazard Determinations

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-03-06

    ...; Internal Agency Docket No. FEMA-B-1296] Proposed Flood Hazard Determinations AGENCY: Federal Emergency Management Agency, DHS. ACTION: Notice. SUMMARY: Comments are requested on proposed flood hazard..., Special Flood Hazard Area (SFHA) boundary or zone designation, or regulatory floodway on the Flood...

  3. True gender ratios and stereotype rating norms

    PubMed Central

    Garnham, Alan; Doehren, Sam; Gygax, Pascal

    2015-01-01

    We present a study comparing, in English, perceived distributions of men and women in 422 named occupations with actual real world distributions. The first set of data was obtained from previous a large-scale norming study, whereas the second set was mostly drawn from UK governmental sources. In total, real world ratios for 290 occupations were obtained for our perceive vs. real world comparison, of which 205 were deemed to be unproblematic. The means for the two sources were similar and the correlation between them was high, suggesting that people are generally accurate at judging real gender ratios, though there were some notable exceptions. Beside this correlation, some interesting patterns emerged from the two sources, suggesting some response strategies when people complete norming studies. We discuss these patterns in terms of the way real world data might complement norming studies in determining gender stereotypicality. PMID:26257681

  4. Association of triglyceride-to-high density lipoprotein cholesterol ratio to cardiorespiratory fitness in men.

    PubMed

    Vega, Gloria Lena; Grundy, Scott M; Barlow, Carolyn E; Leonard, David; Willis, Benjamin L; DeFina, Laura F; Farrell, Stephen W

    Both triglyceride-to-high density lipoprotein cholesterol (TG/HDL-C) and cardiorespiratory fitness (CRF) impart risk for all-cause morbidity and mortality independently of conventional risk factors. To determine prevalence and/or incidence of high TG/HDL-C ratio in men with low CRF. Clinical characteristics and CRF were used to determine prevalence of a TG/HDL-C ratio ≥ 3.5 (high ratio) in 13,954 men of the Cooper Center Longitudinal Study. High-ratio conversion was determined in 10,424 men with normal baseline TG/HDL-C ratio. Hazard ratio (HR) of incident high TG/HDL-C was adjusted for age and waist girth. Men with low CRF had the highest prevalence of a high TG/HDL-C ratio. In the population with normal TG/HDL-C, age-adjusted HR of incident high TG/HDL-C ratio was 2.77 times higher in men with lowest CRF than in those with highest CRF. Incidence of conversion of normal to high ratio was 5.5% per year in low CRF population, compared with 1.7% in high CRF subjects. Incidence HR was independent of waist girth. Men who converted from normal to high TG/HDL-C ratio during the follow-up period had increased number of metabolic risk factors and a higher prevalence of metabolic syndrome. Men who did not convert to a high TG/HDL-C ratio retained a low prevalence of metabolic syndrome risk factors. A high TG/HDL-C ratio is common in men with low CRF. Metabolic syndrome also is common among those with a high ratio. Copyright © 2016 National Lipid Association. All rights reserved.

  5. 48 CFR 252.223-7001 - Hazard warning labels.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...

  6. 48 CFR 252.223-7001 - Hazard warning labels.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...

  7. 48 CFR 252.223-7001 - Hazard warning labels.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...

  8. 48 CFR 252.223-7001 - Hazard warning labels.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...

  9. 48 CFR 252.223-7001 - Hazard warning labels.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Hazardous Material Identification and Material Safety Data clause of this contract. (b) The Contractor shall label the item package (unit container) of any hazardous material to be delivered under this contract in... which hazardous material listed in the Hazardous Material Identification and Material Safety Data clause...

  10. Gender differences in hazardous drinking among middle-aged in Europe: the role of social context and women's empowerment.

    PubMed

    Bosque-Prous, Marina; Espelt, Albert; Borrell, Carme; Bartroli, Montse; Guitart, Anna M; Villalbí, Joan R; Brugal, M Teresa

    2015-08-01

    The aim of this study was to estimate the magnitude of gender differences in hazardous drinking among middle-aged people and to analyse whether these differences are associated with contextual factors, such as public policies or socioeconomic factors. Cross-sectional design. The study population included 50- to 64-year-old residents of 16 European countries who participated in the Survey of Health, Ageing and Retirement in Europe project conducted in 2010-12 (n = 26 017). We estimated gender differences in hazardous drinking in each country. To determine whether different social context or women's empowerment variables were associated with gender differences in hazardous drinking, we fitted multilevel Poisson regression models adjusted for various individual and country-level variables, which yielded prevalence ratios and their 95% confidence intervals (95% CI). Prevalence of hazardous drinking was significantly higher in men than women [30.2% (95% CI: 29.1-31.4%) and 18.6% (95% CI: 17.7-19.4%), respectively] in most countries, although the extent of these differences varied between countries. Among individuals aged 50-64 years in Europe, risk of becoming a hazardous drinker was 1.69 times higher (95% CI: 1.45-1.97) in men, after controlling for individual and country-level variables. We also found that lower values of the gender empowerment measure and higher unemployment rates were associated with higher gender differences in hazardous drinking. Countries with the greatest gender differences in hazardous drinking were those with the most restrictions on women's behaviour, and the greatest gender inequalities in daily life. Lower gender differences in hazardous drinking seem to be related to higher consumption among women. © The Author 2015. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  11. Hydrotreater/Distillation Column Hazard Analysis Report Rev. 2

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lowry, Peter P.; Wagner, Katie A.

    This project Hazard and Risk Analysis Report contains the results of several hazard analyses and risk assessments. An initial assessment was conducted in 2012, which included a multi-step approach ranging from design reviews to a formal What-If hazard analysis. A second What-If hazard analysis was completed during February 2013 to evaluate the operation of the hydrotreater/distillation column processes to be installed in a process enclosure within the Process Development Laboratory West (PDL-West) facility located on the PNNL campus. The qualitative analysis included participation of project and operations personnel and applicable subject matter experts. The analysis identified potential hazardous scenarios, eachmore » based on an initiating event coupled with a postulated upset condition. The unmitigated consequences of each hazardous scenario were generally characterized as a process upset; the exposure of personnel to steam, vapors or hazardous material; a spray or spill of hazardous material; the creation of a flammable atmosphere; or an energetic release from a pressure boundary.« less

  12. ImmunoRatio: a publicly available web application for quantitative image analysis of estrogen receptor (ER), progesterone receptor (PR), and Ki-67

    PubMed Central

    2010-01-01

    Introduction Accurate assessment of estrogen receptor (ER), progesterone receptor (PR), and Ki-67 is essential in the histopathologic diagnostics of breast cancer. Commercially available image analysis systems are usually bundled with dedicated analysis hardware and, to our knowledge, no easily installable, free software for immunostained slide scoring has been described. In this study, we describe a free, Internet-based web application for quantitative image analysis of ER, PR, and Ki-67 immunohistochemistry in breast cancer tissue sections. Methods The application, named ImmunoRatio, calculates the percentage of positively stained nuclear area (labeling index) by using a color deconvolution algorithm for separating the staining components (diaminobenzidine and hematoxylin) and adaptive thresholding for nuclear area segmentation. ImmunoRatio was calibrated using cell counts defined visually as the gold standard (training set, n = 50). Validation was done using a separate set of 50 ER, PR, and Ki-67 stained slides (test set, n = 50). In addition, Ki-67 labeling indexes determined by ImmunoRatio were studied for their prognostic value in a retrospective cohort of 123 breast cancer patients. Results The labeling indexes by calibrated ImmunoRatio analyses correlated well with those defined visually in the test set (correlation coefficient r = 0.98). Using the median Ki-67 labeling index (20%) as a cutoff, a hazard ratio of 2.2 was obtained in the survival analysis (n = 123, P = 0.01). ImmunoRatio was shown to adapt to various staining protocols, microscope setups, digital camera models, and image acquisition settings. The application can be used directly with web browsers running on modern operating systems (e.g., Microsoft Windows, Linux distributions, and Mac OS). No software downloads or installations are required. ImmunoRatio is open source software, and the web application is publicly accessible on our website. Conclusions We anticipate that free web applications

  13. ImmunoRatio: a publicly available web application for quantitative image analysis of estrogen receptor (ER), progesterone receptor (PR), and Ki-67.

    PubMed

    Tuominen, Vilppu J; Ruotoistenmäki, Sanna; Viitanen, Arttu; Jumppanen, Mervi; Isola, Jorma

    2010-01-01

    Accurate assessment of estrogen receptor (ER), progesterone receptor (PR), and Ki-67 is essential in the histopathologic diagnostics of breast cancer. Commercially available image analysis systems are usually bundled with dedicated analysis hardware and, to our knowledge, no easily installable, free software for immunostained slide scoring has been described. In this study, we describe a free, Internet-based web application for quantitative image analysis of ER, PR, and Ki-67 immunohistochemistry in breast cancer tissue sections. The application, named ImmunoRatio, calculates the percentage of positively stained nuclear area (labeling index) by using a color deconvolution algorithm for separating the staining components (diaminobenzidine and hematoxylin) and adaptive thresholding for nuclear area segmentation. ImmunoRatio was calibrated using cell counts defined visually as the gold standard (training set, n = 50). Validation was done using a separate set of 50 ER, PR, and Ki-67 stained slides (test set, n = 50). In addition, Ki-67 labeling indexes determined by ImmunoRatio were studied for their prognostic value in a retrospective cohort of 123 breast cancer patients. The labeling indexes by calibrated ImmunoRatio analyses correlated well with those defined visually in the test set (correlation coefficient r = 0.98). Using the median Ki-67 labeling index (20%) as a cutoff, a hazard ratio of 2.2 was obtained in the survival analysis (n = 123, P = 0.01). ImmunoRatio was shown to adapt to various staining protocols, microscope setups, digital camera models, and image acquisition settings. The application can be used directly with web browsers running on modern operating systems (e.g., Microsoft Windows, Linux distributions, and Mac OS). No software downloads or installations are required. ImmunoRatio is open source software, and the web application is publicly accessible on our website. We anticipate that free web applications, such as ImmunoRatio, will make the

  14. Exposure to hazardous volatile pollutants back diffusing from automobile exhaust systems.

    PubMed

    Rahman, Md Mahmudur; Kim, Ki-Hyun

    2012-11-30

    As back diffusion gases from automobiles are significant sources of in-vehicular pollution, we investigated eight automobiles, five for back diffusion (driving) measurements and three for reference conditions (non-driving). To characterize the back diffusion emission conditions, seven volatile organic compounds (VOC) and four carbonyl compounds (CCs) were measured along with dilution-to-threshold (D/T) ratio. The data obtained from back diffusion measurements were examined after having been divided into three subcategories: (i) driving and non-driving, (ii) with and without automobile upgrading (sealing the inner line), and (iii) differences in CO emission levels. Among the VOCs, the concentrations of toluene (T) was found to be the highest (range: 13.6-155 ppb), while benzene (0.19-1.47 ppb) was hardly distinguishable from its ambient levels. Other VOCs (xylene, trimethylbenzene, and styrene) were generally below <1 ppb. Unlike VOCs, the concentrations (ppb) of CCs were seen at fairly enhanced levels: 30.1-95 (formaldehyde), 34.6-87.2 (acetaldehyde), 4.56-34.7 (propionaldehyde), and 3.45-68.8 (butyraldehyde). The results of our study suggest that the back diffusion phenomenon, if occurring, can deteriorate in-vehicle air, especially with the most imminent health hazards from a compound such as formaldehyde in view of its exceedance pattern over common guidelines. Copyright © 2012 Elsevier B.V. All rights reserved.

  15. Coastal Hazards.

    ERIC Educational Resources Information Center

    Vandas, Steve

    1998-01-01

    Focuses on hurricanes and tsunamis and uses these topics to address other parts of the science curriculum. In addition to a discussion on beach erosion, a poster is provided that depicts these natural hazards that threaten coastlines. (DDR)

  16. 46 CFR 71.25-45 - Fire hazards.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Fire hazards. 71.25-45 Section 71.25-45 Shipping COAST... Inspection § 71.25-45 Fire hazards. (a) At each annual inspection, the inspector shall examine the tank tons... fire hazard. (b) [Reserved] ...

  17. Removal of radioactive and other hazardous material from fluid waste

    DOEpatents

    Tranter, Troy J [Idaho Falls, ID; Knecht, Dieter A [Idaho Falls, ID; Todd, Terry A [Aberdeen, ID; Burchfield, Larry A [W. Richland, WA; Anshits, Alexander G [Krasnoyarsk, RU; Vereshchagina, Tatiana [Krasnoyarsk, RU; Tretyakov, Alexander A [Zheleznogorsk, RU; Aloy, Albert S [St. Petersburg, RU; Sapozhnikova, Natalia V [St. Petersburg, RU

    2006-10-03

    Hollow glass microspheres obtained from fly ash (cenospheres) are impregnated with extractants/ion-exchangers and used to remove hazardous material from fluid waste. In a preferred embodiment the microsphere material is loaded with ammonium molybdophosphonate (AMP) and used to remove radioactive ions, such as cesium-137, from acidic liquid wastes. In another preferred embodiment, the microsphere material is loaded with octyl(phenyl)-N-N-diisobutyl-carbamoylmethylphosphine oxide (CMPO) and used to remove americium and plutonium from acidic liquid wastes.

  18. Analysis and improved design considerations for airborne pulse Doppler radar signal processing in the detection of hazardous windshear

    NASA Technical Reports Server (NTRS)

    Lee, Jonggil

    1990-01-01

    High resolution windspeed profile measurements are needed to provide reliable detection of hazardous low altitude windshear with an airborne pulse Doppler radar. The system phase noise in a Doppler weather radar may degrade the spectrum moment estimation quality and the clutter cancellation capability which are important in windshear detection. Also the bias due to weather return Doppler spectrum skewness may cause large errors in pulse pair spectral parameter estimates. These effects are analyzed for the improvement of an airborne Doppler weather radar signal processing design. A method is presented for the direct measurement of windspeed gradient using low pulse repetition frequency (PRF) radar. This spatial gradient is essential in obtaining the windshear hazard index. As an alternative, the modified Prony method is suggested as a spectrum mode estimator for both the clutter and weather signal. Estimation of Doppler spectrum modes may provide the desired windshear hazard information without the need of any preliminary processing requirement such as clutter filtering. The results obtained by processing a NASA simulation model output support consideration of mode identification as one component of a windshear detection algorithm.

  19. Countermeasures to Hazardous Chemicals,

    DTIC Science & Technology

    1989-04-01

    Chemical Engineers (AIChE), 3. Hazardous Materials Advisery, Council (HMAC), (not the same as the Memphis/Shelby County HMAC), 4. American Petroleum...retired chemical engineers , will volunteer to avos t the I wcal communities in their pl. ining efforts. S1i !NSTITrTE OF HAZARDOUS MATERIALS MANAGEMENT The... chemicals may be considered to be a man-made wind. Such large gas volumes can be produced by blowcr equipment incorporating surplus jet engines . Such blowers

  20. Noise and contrast comparison of visual and infrared images of hazards as seen inside an automobile

    NASA Astrophysics Data System (ADS)

    Meitzler, Thomas J.; Bryk, Darryl; Sohn, Eui J.; Lane, Kimberly; Bednarz, David; Jusela, Daniel; Ebenstein, Samuel; Smith, Gregory H.; Rodin, Yelena; Rankin, James S., II; Samman, Amer M.

    2000-06-01

    The purpose of this experiment was to quantitatively measure driver performance for detecting potential road hazards in visual and infrared (IR) imagery of road scenes containing varying combinations of contrast and noise. This pilot test is a first step toward comparing various IR and visual sensors and displays for the purpose of an enhanced vision system to go inside the driver compartment. Visible and IR road imagery obtained was displayed on a large screen and on a PC monitor and subject response times were recorded. Based on the response time, detection probabilities were computed and compared to the known time of occurrence of a driving hazard. The goal was to see what combinations of sensor, contrast and noise enable subjects to have a higher detection probability of potential driving hazards.