Geology and occurrence of ground water in Lyon County, Minnesota
Rodis, Harry G.
1963-01-01
Large quantities of ground water are available from melt-water channels in the county. Moderate quantities, adequate for domestic and small industrial needs, are available from many of the small isolated deposits of sand and gravel in the till. Small quantities of ground water, adequate only for domestic supply, generally can be obtained from Cretaceous sandstone.
Jambor, Helena; Mejstrik, Pavel; Tomancak, Pavel
2016-01-01
Isolation of large quantities of tissue from organisms is essential for many techniques such as genome-wide screens and biochemistry. However, obtaining large quantities of tissues or cells is often the rate-limiting step when working in vivo. Here, we present a rapid method that allows the isolation of intact, single egg chambers at various developmental stages from ovaries of adult female Drosophila flies. The isolated egg chambers are amenable for a variety of procedures such as fluorescent in situ hybridization, RNA isolation, extract preparation, or immunostaining. Isolation of egg chambers from adult flies can be completed in 5 min and results, depending on the input amount of flies, in several milliliters of material. The isolated egg chambers are then further processed depending on the exact requirements of the subsequent application. We describe high-throughput in situ hybridization in 96-well plates as example application for the mass-isolated egg chambers.
Mass culture of photobacteria to obtain luciferase
NASA Technical Reports Server (NTRS)
Chappelle, E. W.; Picciolo, G. L.; Rich, E., Jr.
1969-01-01
Inoculating preheated trays containing nutrient agar with photobacteria provides a means for mass culture of aerobic microorganisms in order to obtain large quantities of luciferase. To determine optimum harvest time, growth can be monitored by automated light-detection instrumentation.
48 CFR 245.7302-5 - Mailing lists.
Code of Federal Regulations, 2010 CFR
2010-10-01
... Mailing lists. (a) The plant clearance officer will ensure the contractor solicits a sufficient number of bidders to obtain adequate competition. (b) When large quantities of property, special commodities, or unusual geographic locations are involved, the plant clearance officer is encouraged to obtain additional...
Quantum confinement effects on superconducting properties of Lead nanocrystals
NASA Astrophysics Data System (ADS)
Aubin, Herve; Moreira, Helena; Mahler, Benoit; Dubertret, Benoit
2008-03-01
We developed a new chemical synthesis method for producing large quantities of monodispersed lead (Pb) nanocrystals. They are obtained from the alcohol reduction of a mixture of two lead carboxylates with alkyl chains of different lengths, dissolved in a high temperature solvent. The nanocrystals obtained are protected from oxydation and aggregation by long chain fatty acids and their diameter can be tuned to reach values as low as 10 nm. Our results suggest that monodispersed particules are obtained when nucleation and growth occur at distincts temperatures, possibly as a consequence of different reactivities of the two lead carboxylates used in the solution. Owing to the large quantities of monodispersed particles produced, thermodynamics studies as function of particles diameter become possible. In particular, we will present a study of the effect of quantum confinement on superconducting properties of these Pb particles through SQUID magnetometry measurements.
An Analysis of the Second Project High Water Data
NASA Technical Reports Server (NTRS)
Woodbridge, David D.; Lasater, James A.; Fultz, Bennett M.; Clark, Richard E.; Wylie, Nancy
1963-01-01
Early in 1962 NASA established "Project High Water" to investigate the sudden release of large quantities of water into the upper atmosphere. The primary objectives of these experiments were to obtain information on the behavior of liquids released in the ionosphere and the localized effects on the ionosphere produced by the injection of large quantities of water. The data obtained in the two (2) Project High Water experiments have yielded an extensive amount of information concerning the complex phenomena associated with the sudden release of liquids in the Ionosphere. The detailed analysis of data obtained during the second Project High Water experiment (i.e., the third Saturn I vehicle test or SA-3) presented in this report demonstrates that the objectives of the Project High Water were achieved. In addition, the Project High Water has provided essential information relevant to a number of problems vital to manned explorations of space.
The production of multiprotein complexes in insect cells using the baculovirus expression system.
Abdulrahman, Wassim; Radu, Laura; Garzoni, Frederic; Kolesnikova, Olga; Gupta, Kapil; Osz-Papai, Judit; Berger, Imre; Poterszman, Arnaud
2015-01-01
The production of a homogeneous protein sample in sufficient quantities is an essential prerequisite not only for structural investigations but represents also a rate-limiting step for many functional studies. In the cell, a large fraction of eukaryotic proteins exists as large multicomponent assemblies with many subunits, which act in concert to catalyze specific activities. Many of these complexes cannot be obtained from endogenous source material, so recombinant expression and reconstitution are then required to overcome this bottleneck. This chapter describes current strategies and protocols for the efficient production of multiprotein complexes in large quantities and of high quality, using the baculovirus/insect cell expression system.
Polynomial complexity despite the fermionic sign
NASA Astrophysics Data System (ADS)
Rossi, R.; Prokof'ev, N.; Svistunov, B.; Van Houcke, K.; Werner, F.
2017-04-01
It is commonly believed that in unbiased quantum Monte Carlo approaches to fermionic many-body problems, the infamous sign problem generically implies prohibitively large computational times for obtaining thermodynamic-limit quantities. We point out that for convergent Feynman diagrammatic series evaluated with a recently introduced Monte Carlo algorithm (see Rossi R., arXiv:1612.05184), the computational time increases only polynomially with the inverse error on thermodynamic-limit quantities.
Prediction of Turbulent Temperature Fluctuations in Hot Jets
NASA Technical Reports Server (NTRS)
Debonis, James R.
2017-01-01
Large-eddy simulations were used to investigate turbulent temperature fluctuations and turbulent heat flux in hot jets. A high-resolution finite-difference Navier-Stokes solver, WRLES, was used to compute the flow from a 2-inch round nozzle. Several different flow conditions, consisting of different jet Mach numbers and temperature ratios, were examined. Predictions of mean and fluctuating velocities were compared to previously obtained particle image velocimetry data. Predictions of mean and fluctuating temperature were compared to new data obtained using Raman spectroscopy. Based on the good agreement with experimental data for the individual quantities, the combined quantity turbulent heat flux was examined.
Photosynthesis-related quantities for education and modeling.
Antal, Taras K; Kovalenko, Ilya B; Rubin, Andrew B; Tyystjärvi, Esa
2013-11-01
A quantitative understanding of the photosynthetic machinery depends largely on quantities, such as concentrations, sizes, absorption wavelengths, redox potentials, and rate constants. The present contribution is a collection of numbers and quantities related mainly to photosynthesis in higher plants. All numbers are taken directly from a literature or database source and the corresponding reference is provided. The numerical values, presented in this paper, provide ranges of values, obtained in specific experiments for specific organisms. However, the presented numbers can be useful for understanding the principles of structure and function of photosynthetic machinery and for guidance of future research.
Quantum communication complexity advantage implies violation of a Bell inequality
Buhrman, Harry; Czekaj, Łukasz; Grudka, Andrzej; Horodecki, Michał; Horodecki, Paweł; Markiewicz, Marcin; Speelman, Florian; Strelchuk, Sergii
2016-01-01
We obtain a general connection between a large quantum advantage in communication complexity and Bell nonlocality. We show that given any protocol offering a sufficiently large quantum advantage in communication complexity, there exists a way of obtaining measurement statistics that violate some Bell inequality. Our main tool is port-based teleportation. If the gap between quantum and classical communication complexity can grow arbitrarily large, the ratio of the quantum value to the classical value of the Bell quantity becomes unbounded with the increase in the number of inputs and outputs. PMID:26957600
A Method for Obtaining Large Populations of Synchronized Caenorhabditis elegans Dauer Larvae.
Ow, Maria C; Hall, Sarah E
2015-01-01
The C. elegans dauer is an attractive model with which to investigate fundamental biological questions, such as how environmental cues are sensed and are translated into developmental decisions through a series of signaling cascades that ultimately result in a transformed animal. Here we describe a simple method of using egg white plates to obtain highly synchronized purified dauers that can be used in downstream applications requiring large quantities of dauers or postdauer animals.
Large scale EMF in current sheets induced by tearing modes
NASA Astrophysics Data System (ADS)
Mizerski, Krzysztof A.
2018-02-01
An extension of the analysis of resistive instabilities of a sheet pinch from a famous work by Furth et al (1963 Phys. Fluids 6 459) is presented here, to study the mean electromotive force (EMF) generated by the developing instability. In a Cartesian configuration and in the presence of a current sheet first the boundary layer technique is used to obtain global, matched asymptotic solutions for the velocity and magnetic field and then the solutions are used to calculate the large-scale EMF in the system. It is reported, that in the bulk the curl of the mean EMF is linear in {{j}}0\\cdot {{B}}0, a simple pseudo-scalar quantity constructed from the large-scale quantities.
Chapter 15. transforming lepidopteran insect cells for continuous recombinant protein expression
USDA-ARS?s Scientific Manuscript database
The baculovirus expression vector system (BEVS) is widely used to produce large quantities of recombinant proteins. However, yields of extracellular and membrane-bound proteins obtained with this system often are very low, possibly due to the adverse effects of baculovirus infection on the host ins...
Mahjouri, Najmeh; Ardestani, Mojtaba
2011-01-01
In this paper, two cooperative and non-cooperative methodologies are developed for a large-scale water allocation problem in Southern Iran. The water shares of the water users and their net benefits are determined using optimization models having economic objectives with respect to the physical and environmental constraints of the system. The results of the two methodologies are compared based on the total obtained economic benefit, and the role of cooperation in utilizing a shared water resource is demonstrated. In both cases, the water quality in rivers satisfies the standards. Comparing the results of the two mentioned approaches shows the importance of acting cooperatively to achieve maximum revenue in utilizing a surface water resource while the river water quantity and quality issues are addressed.
Graviton propagator from background-independent quantum gravity.
Rovelli, Carlo
2006-10-13
We study the graviton propagator in Euclidean loop quantum gravity. We use spin foam, boundary-amplitude, and group-field-theory techniques. We compute a component of the propagator to first order, under some approximations, obtaining the correct large-distance behavior. This indicates a way for deriving conventional spacetime quantities from a background-independent theory.
Purification of Pseudomonas aeruginosa Endotoxin by Membrane Partition Chromatography
Rubio, Nazario; Lopez, Rubens
1972-01-01
A procedure is described for obtaining large quantities of purified endotoxin of Pseudomonas aeruginosa by using Diaflo ultrafiltration. This method allowed us to isolate from the protein-lipopolysaccharide complex two low-molecular-weight substances which do not play any antigenic role. It provides a useful tool for immunological purposes. Images PMID:4622818
Preliminary Survey of Icing Conditions Measured During Routine Transcontinental Airline Operation
NASA Technical Reports Server (NTRS)
Perkins, Porter J.
1952-01-01
Icing data collected on routine operations by four DC-4-type aircraft equipped with NACA pressure-type icing-rate meters are presented as preliminary information obtained from a statistical icing data program sponsored by the NACA with the cooperation of many airline companies and the United States Air Force. The program is continuing on a much greater scale to provide large quantities of data from many air routes in the United States and overseas. Areas not covered by established air routes are also being included in the survey. The four aircraft which collected the data presented in this report were operated by United Air Lines over a transcontinental route from January through May, 1951. An analysis of the pressure-type icing-rate meter was satisfactory for collecting statistical data during routine operations. Data obtained on routine flight icing encounters from.these four instrumented aircraft, although insufficient for a conclusive statistical analysis, provide a greater quantity and considerably more realistic information than that obtained from random research flights. A summary of statistical data will be published when the information obtained daring the 1951-52 icing season and that to be obtained during the 1952-53 season can be analyzed and assembled. The 1951-52 data already analyzed indicate that the quantity, quality, and range of icing information being provided by this expanded program should afford a sound basis for ice-protection-system design by defining the important meteorological parameters of the icing cloud.
Numerical investigation of supersonic turbulent boundary layers with high wall temperature
NASA Technical Reports Server (NTRS)
Guo, Y.; Adams, N. A.
1994-01-01
A direct numerical approach has been developed to simulate supersonic turbulent boundary layers. The mean flow quantities are obtained by solving the parabolized Reynolds-averaged Navier-Stokes equations (globally). Fluctuating quantities are computed locally with a temporal direct numerical simulation approach, in which nonparallel effects of boundary layers are partially modeled. Preliminary numerical results obtained at the free-stream Mach numbers 3, 4.5, and 6 with hot-wall conditions are presented. Approximately 5 million grid points are used in all three cases. The numerical results indicate that compressibility effects on turbulent kinetic energy, in terms of dilatational dissipation and pressure-dilatation correlation, are small. Due to the hot-wall conditions the results show significant low Reynolds number effects and large streamwise streaks. Further simulations with a bigger computational box or a cold-wall condition are desirable.
Sijwali, P S; Brinen, L S; Rosenthal, P J
2001-06-01
The Plasmodium falciparum cysteine protease falcipain-2 is a potential new target for antimalarial chemotherapy. In order to obtain large quantities of active falcipain-2 for biochemical and structural analysis, a systematic assessment of optimal parameters for the expression and refolding of the protease was carried out. High-yield expression was achieved using M15(pREP4) Escherichia coli transformed with the pQE-30 plasmid containing a truncated profalcipain-2 construct. Recombinant falcipain-2 was expressed as inclusion bodies, solubilized, and purified by nickel affinity chromatography. A systematic approach was then used to optimize refolding parameters. This approach utilized 100-fold dilutions of reduced and denatured falcipain-2 into 203 different buffers in a microtiter plate format. Refolding efficiency varied markedly. Optimal refolding was obtained in an alkaline buffer containing glycerol or sucrose and equal concentrations of reduced and oxidized glutathione. After optimization of the expression and refolding protocols and additional purification with anion-exchange chromatography, 12 mg of falcipain-2 was obtained from 5 liters of E. coli, and crystals of the protease were grown. The systematic approach described here allowed the rapid evaluation of a large number of expression and refolding conditions and provided milligram quantities of recombinant falcipain-2. Copyright 2001 Academic Press.
2017-05-01
large sand bed river, with seven sites representing increasingly larger flows along the river length. The data set will be very useful for additional...quantity, quality , and types of data that can be obtained for the study of natural phenomenon. The study of riverine sedimentation is no exception...detail than in previous years. Additionally, new methodologies have been developed that allow the computation of bed-load transport in large sand bed
Hod, Idan; Sampson, Matthew D.; Deria, Pravas; ...
2015-09-18
Realization of heterogeneous electrochemical CO 2-to-fuel conversion via molecular catalysis under high-flux conditions requires the assembly of large quantities of reactant-accessible catalysts on conductive surfaces. As a proof of principle, we demonstrate that electrophoretic deposition of thin films of an appropriately chosen metal–organic framework (MOF) material is an effective method for immobilizing the needed quantity of catalyst. For electrocatalytic CO 2 reduction, we used a material that contains functionalized Fe-porphyrins as catalytically competent, redox-conductive linkers. The approach yields a high effective surface coverage of electrochemically addressable catalytic sites (~10 15 sites/cm 2). The chemical products of the reduction, obtained withmore » ~100% Faradaic efficiency, are mixtures of CO and H 2. The results validate the strategy of using MOF chemistry to obtain porous, electrode-immobilized, networks of molecular catalysts having competency for energy-relevant electrochemical reactions.« less
Current databases on biological variation: pros, cons and progress.
Ricós, C; Alvarez, V; Cava, F; García-Lario, J V; Hernández, A; Jiménez, C V; Minchinela, J; Perich, C; Simón, M
1999-11-01
A database with reliable information to derive definitive analytical quality specifications for a large number of clinical laboratory tests was prepared in this work. This was achieved by comparing and correlating descriptive data and relevant observations with the biological variation information, an approach that had not been used in the previous efforts of this type. The material compiled in the database was obtained from published articles referenced in BIOS, CURRENT CONTENTS, EMBASE and MEDLINE using "biological variation & laboratory medicine" as key words, as well as books and doctoral theses provided by their authors. The database covers 316 quantities and reviews 191 articles, fewer than 10 of which had to be rejected. The within- and between-subject coefficients of variation and the subsequent desirable quality specifications for precision, bias and total error for all the quantities accepted are presented. Sex-related stratification of results was justified for only four quantities and, in these cases, quality specifications were derived from the group with lower within-subject variation. For certain quantities, biological variation in pathological states was higher than in the healthy state. In these cases, quality specifications were derived only from the healthy population (most stringent). Several quantities (particularly hormones) have been treated in very few articles and the results found are highly discrepant. Therefore, professionals in laboratory medicine should be strongly encouraged to study the quantities for which results are discrepant, the 90 quantities described in only one paper and the numerous quantities that have not been the subject of study.
The characterization of high-density polyethylene/organoclay nanocomposites
NASA Astrophysics Data System (ADS)
Rodrigues, Tathiane Cordeiro; Tavares, Maria Inês Bruno; Soares, Igor Lopes; Moreira, Ana M.
2009-01-01
Polymeric nanocomposites, which are hybrids of polymers and modified inorganic clay with organic surfactants, are extremely attractive in both science and industry. These materials present improvements in such polymer properties as modulus, heat capacity, thermal stability, flame resistance, and so on. Research has been conducted in recent decades to obtain high-quality materials that can be used in applications like food packing, car components, and combustible cells. Polymeric nanocomposites present many advantages in relation to composites due to the quantity of filler added to the polymer and also to the improved properties. In a composite, the quantity of filler must be as high as possible (i.e., over 30%). In the polymeric nanocomposite the quantity of filler varies from 1% to 5% because of the nanosize of the particles. These nanoparticles often have a large surface area that results in improved polymer-matrix properties.
Multi-look fusion identification: a paradigm shift from quality to quantity in data samples
NASA Astrophysics Data System (ADS)
Wong, S.
2009-05-01
A multi-look identification method known as score-level fusion is found to be capable of achieving very high identification accuracy, even when low quality target signatures are used. Analysis using measured ground vehicle radar signatures has shown that a 97% correct identification rate can be achieved using this multi-look fusion method; in contrast, only a 37% accuracy rate is obtained when single target signature input is used. The results suggest that quantity can be used to replace quality of the target data in improving identification accuracy. With the advent of sensor technology, a large amount of target signatures of marginal quality can be captured routinely. This quantity over quality approach allows maximum exploitation of the available data to improve the target identification performance and this could have the potential of being developed into a disruptive technology.
USDA-ARS?s Scientific Manuscript database
In addition to microarray technology, which provides a robust method to study protein function in a rapid, economical, and proteome-wide fashion, plasmid-based functional proteomics is an important technology for rapidly obtaining large quantities of protein and determining protein function across a...
Industrial Hardening Demonstration.
1980-09-01
products are obtained without simultaneous formation of coke and large quantities of gas. Purification Processes Sulfuric acid treatment removes sulfur by...attack ranged from 6 to 18 psi at six plants; two plants were rendered essentially invulnerable because of complete removal to a host area; and one...hazards. Such methods include: removal of conbustibles and potential missiles; strengthening or shielding of equipment against missiles and * "Crisis
A simulation of probabilistic wildfire risk components for the continental United States
Mark A. Finney; Charles W. McHugh; Isaac C. Grenfell; Karin L. Riley; Karen C. Short
2011-01-01
This simulation research was conducted in order to develop a large-fire risk assessment system for the contiguous land area of the United States. The modeling system was applied to each of 134 Fire Planning Units (FPUs) to estimate burn probabilities and fire size distributions. To obtain stable estimates of these quantities, fire ignition and growth was simulated for...
A posteriori error estimation for multi-stage Runge–Kutta IMEX schemes
DOE Office of Scientific and Technical Information (OSTI.GOV)
Chaudhry, Jehanzeb H.; Collins, J. B.; Shadid, John N.
Implicit–Explicit (IMEX) schemes are widely used for time integration methods for approximating solutions to a large class of problems. In this work, we develop accurate a posteriori error estimates of a quantity-of-interest for approximations obtained from multi-stage IMEX schemes. This is done by first defining a finite element method that is nodally equivalent to an IMEX scheme, then using typical methods for adjoint-based error estimation. Furthermore, the use of a nodally equivalent finite element method allows a decomposition of the error into multiple components, each describing the effect of a different portion of the method on the total error inmore » a quantity-of-interest.« less
A posteriori error estimation for multi-stage Runge–Kutta IMEX schemes
Chaudhry, Jehanzeb H.; Collins, J. B.; Shadid, John N.
2017-02-05
Implicit–Explicit (IMEX) schemes are widely used for time integration methods for approximating solutions to a large class of problems. In this work, we develop accurate a posteriori error estimates of a quantity-of-interest for approximations obtained from multi-stage IMEX schemes. This is done by first defining a finite element method that is nodally equivalent to an IMEX scheme, then using typical methods for adjoint-based error estimation. Furthermore, the use of a nodally equivalent finite element method allows a decomposition of the error into multiple components, each describing the effect of a different portion of the method on the total error inmore » a quantity-of-interest.« less
NASA Astrophysics Data System (ADS)
Daluge, D. R.; Ruedger, W. H.
1981-06-01
Problems encountered in testing onboard signal processing hardware designed to achieve radiometric and geometric correction of satellite imaging data are considered. These include obtaining representative image and ancillary data for simulation and the transfer and storage of a large quantity of image data at very high speed. The high resolution, high speed preprocessing of LANDSAT-D imagery is considered.
Tunable heat transfer with smart nanofluids.
Bernardin, Michele; Comitani, Federico; Vailati, Alberto
2012-06-01
Strongly thermophilic nanofluids are able to transfer either small or large quantities of heat when subjected to a stable temperature difference. We investigate the bistability diagram of the heat transferred by this class of nanofluids. We show that bistability can be exploited to obtain a controlled switching between a conductive and a convective regime of heat transfer, so as to achieve a controlled modulation of the heat flux.
Improvement of core drill methods
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gatz, J.L.
1975-07-01
This report documents results of a program to evaluate effectiveness of more or less conventional subsurface samplers in obtaining representative and undisturbed samples of noncohesive alluvial materials containing large quantities of gravels and cobbles. This is the first phase of a research program to improve core drill methods. Samplers evaluated consisted of the Lawrence Livermore Laboratory membrane sampler, 4-in. Denison sampler, 6-in. Dension sampler, 5-in. Modified Denison sampler, and 3-in. thinwall drive tube. Small representative samples were obtained with the Dension samplers; no undisturbed samples were obtained. The field work was accomplished in the Rhodes Canyon area, White Sands Misslemore » Range, New Mexico.« less
Explosion Hazards Associated with Spills of Large Quantities of Hazardous Materials. Phase I
1974-10-01
quantities of hazardous material such as liquified natural gas ( LNG ), liquified petroleum gils (LPG), or ethylene. The principal results are (1) a...associated with spills of large quantities of hazardous material such as liquified natural gas ( LNG ), liquified petroleum gas (LPG), or ethylene. The...liquified natural gas ( LNG ). Unfortunately, as the quantity of material shipped at one time increases, so does the potential hazard associated with
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhang, Huili; Liu, Zhifang; Yang, Jiaqin
2014-09-15
Graphical abstract: Generally, large acid quantity and high temperature are beneficial to the formation of anhydrous WO3, but the acidity effect on the crystal phase is weaker than that of temperature. Large acid quantity is found helpful to the oriented growth of tungsten oxides, forming a nanoplate-like product. - Highlights: • Large acid quantity is propitious to the oriented growth of a WO{sub 3} nanoplate. • Effect of acid quantity on crystal phases of products is weaker than that of temperature. • One step hydrothermal synthesis of WO{sub 3} is facile and can be easily scaled up. • A WO{submore » 3} nanoplate shows a fast response and distinct sensing selectivity to acetone gas. - Abstract: WO{sub 3} nanostructures were successfully synthesized by a facile hydrothermal method using Na{sub 2}WO{sub 4}·2H{sub 2}O and HNO{sub 3} as raw materials. They are characterized by X-ray diffraction (XRD), scanning electron microscope (SEM) and transmission electron microscope (TEM). The specific surface area was obtained from N{sub 2} adsorption–desorption isotherm. The effects of the amount of HNO{sub 3}, hydrothermal temperature and reaction time on the crystal phases and morphologies of the WO{sub 3} nanostructures were investigated in detail, and the reaction mechanism was discussed. Large amount of acid is found for the first time to be helpful to the oriented growth of tungsten oxides, forming nanoplate-like products, while hydrothermal temperature has more influence on the crystal phase of the product. Gas-sensing properties of the series of as-prepared WO{sub 3} nanoplates were tested by means of acetone, ethanol, formaldehyde and ammonia. One of the WO{sub 3} nanoplates with high specific surface area and high crystallinity displays high sensitivity, fast response and distinct sensing selectivity to acetone gas.« less
Enforcement of food packaging legislation.
van Lierop, J B
1997-01-01
A survey of the results of the analysis of samples of packaging materials, obtained from the Dutch market during the last 5 years is presented. The diethylether extracts of food contact polymers were analysed by GC-MS according to the Dutch testing system. Lists of the identified constituents in the extracts of polystyrene (PS), polypropylene (PP), polyethylene (PE), polyethylene terephthlate (PET) and polyvinylchloride (PVC) are given. More than 50 constituents were identified in the more than 1000 samples investigated. An estimation of the quantities of the extracted constituents has been made. In PVC the following compounds were present in relatively large quantities (10 times the height of the internal standards): diethylhexyladipate, dinonylphthalate, and other phthalates. However 68% of the extracts contained no peaks higher than the internal standards.
Accelerating Full Configuration Interaction Calculations for Nuclear Structure
DOE Office of Scientific and Technical Information (OSTI.GOV)
Yang, Chao; Sternberg, Philip; Maris, Pieter
2008-04-14
One of the emerging computational approaches in nuclear physics is the full configuration interaction (FCI) method for solving the many-body nuclear Hamiltonian in a sufficiently large single-particle basis space to obtain exact answers - either directly or by extrapolation. The lowest eigenvalues and correspondingeigenvectors for very large, sparse and unstructured nuclear Hamiltonian matrices are obtained and used to evaluate additional experimental quantities. These matrices pose a significant challenge to the design and implementation of efficient and scalable algorithms for obtaining solutions on massively parallel computer systems. In this paper, we describe the computational strategies employed in a state-of-the-art FCI codemore » MFDn (Many Fermion Dynamics - nuclear) as well as techniques we recently developed to enhance the computational efficiency of MFDn. We will demonstrate the current capability of MFDn and report the latest performance improvement we have achieved. We will also outline our future research directions.« less
ERIC Educational Resources Information Center
General Accounting Office, Washington, DC.
The District of Columbia Public Schools system has taken action to ensure that supply items will be obtained at the most competitive prices. Because lack of storage facilities prevented bulk purchase of emergency items at competitive rates, the Division of Buildings and Grounds has remodeled a building as a warehouse to store large quantities of…
NASA Technical Reports Server (NTRS)
Daluge, D. R.; Ruedger, W. H.
1981-01-01
Problems encountered in testing onboard signal processing hardware designed to achieve radiometric and geometric correction of satellite imaging data are considered. These include obtaining representative image and ancillary data for simulation and the transfer and storage of a large quantity of image data at very high speed. The high resolution, high speed preprocessing of LANDSAT-D imagery is considered.
Multi-scale comparison of source parameter estimation using empirical Green's function approach
NASA Astrophysics Data System (ADS)
Chen, X.; Cheng, Y.
2015-12-01
Analysis of earthquake source parameters requires correction of path effect, site response, and instrument responses. Empirical Green's function (EGF) method is one of the most effective methods in removing path effects and station responses by taking the spectral ratio between a larger and smaller event. Traditional EGF method requires identifying suitable event pairs, and analyze each event individually. This allows high quality estimations for strictly selected events, however, the quantity of resolvable source parameters is limited, which challenges the interpretation of spatial-temporal coherency. On the other hand, methods that exploit the redundancy of event-station pairs are proposed, which utilize the stacking technique to obtain systematic source parameter estimations for a large quantity of events at the same time. This allows us to examine large quantity of events systematically, facilitating analysis of spatial-temporal patterns, and scaling relationship. However, it is unclear how much resolution is scarified during this process. In addition to the empirical Green's function calculation, choice of model parameters and fitting methods also lead to biases. Here, using two regional focused arrays, the OBS array in the Mendocino region, and the borehole array in the Salton Sea geothermal field, I compare the results from the large scale stacking analysis, small-scale cluster analysis, and single event-pair analysis with different fitting methods to systematically compare the results within completely different tectonic environment, in order to quantify the consistency and inconsistency in source parameter estimations, and the associated problems.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ishida, Hideshi, E-mail: ishida@me.es.osaka-u.ac.jp
2014-06-15
In this study, a family of local quantities defined on each partition and its averaging on a macroscopic small region, site, are defined on a multibaker chain system. On its averaged quantities, a law of order estimation in the bulk system is proved, making it possible to estimate the order of the quantities with respect to the representative partition scale parameter Δ. Moreover, the form of the leading-order terms of the averaged quantities is obtained, and the form enables us to have the macroscopic quantity in the continuum limit, as Δ → 0, and to confirm its partitioning independency. Thesemore » deliverables fully explain the numerical results obtained by Ishida, consistent with the irreversible thermodynamics.« less
Lunar exploration for resource utilization
NASA Technical Reports Server (NTRS)
Duke, Michael B.
1992-01-01
The strategy for developing resources on the Moon depends on the stage of space industrialization. A case is made for first developing the resources needed to provide simple materials required in large quantities for space operations. Propellants, shielding, and structural materials fall into this category. As the enterprise grows, it will be feasible to develop additional sources - those more difficult to obtain or required in smaller quantities. Thus, the first materials processing on the Moon will probably take the abundant lunar regolith, extract from it major mineral or glass species, and do relatively simple chemical processing. We need to conduct a lunar remote sensing mission to determine the global distribution of features, geophysical properties, and composition of the Moon, information which will serve as the basis for detailed models of and engineering decisions about a lunar mine.
A predictive model for failure properties of thermoset resins
NASA Technical Reports Server (NTRS)
Caruthers, James M.; Bowles, Kenneth J.
1989-01-01
A predictive model for the three-dimensional failure behavior of engineering polymers has been developed in a recent NASA-sponsored research program. This model acknowledges the underlying molecular deformation mechanisms and thus accounts for the effects of different chemical compositions, crosslink density, functionality of the curing agent, etc., on the complete nonlinear stress-strain response including yield. The material parameters required by the model can be determined from test-tube quantities of a new resin in only a few days. Thus, we can obtain a first-order prediction of the applicability of a new resin for an advanced aerospace application without synthesizing the large quantities of material needed for failure testing. This technology will effect order-of-magnitude reductions in the time and expense required to develop new engineering polymers.
A small quantity of sodium arsenite will kill large cull hardwoods
Francis M. Rushmore
1956-01-01
Although it is well known that sodium arsenite is an effective silvicide, forestry literature contains little information about the minimum quantities of this chemical that are required to kill large cull trees. Such information would be of value because if small quantities of a chemical will produce satisfactory results, small holes or frills in the tree will hold it...
Development of a Charged-Particle Accumulator Using an RF Confinement Method
2007-03-12
antiparticles (antiprotons and positrons), and to produce a large quantity of antimatter . Antihydrogen atoms have recently been produced using Penning...ultimate goal is to trap a large number of antiparticles and to produce a large quantity of antimatter . 15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF
Mauchline, T H; Mohan, S; Davies, K G; Schaff, J E; Opperman, C H; Kerry, B R; Hirsch, P R
2010-05-01
To establish a reliable protocol to extract DNA from Pasteuria penetrans endospores for use as template in multiple strand amplification, thus providing sufficient material for genetic analyses. To develop a highly sensitive PCR-based diagnostic tool for P. penetrans. An optimized method to decontaminate endospores, release and purify DNA enabled multiple strand amplification. DNA purity was assessed by cloning and sequencing gyrB and 16S rRNA gene fragments obtained from PCR using generic primers. Samples indicated to be 100%P. penetrans by the gyrB assay were estimated at 46% using the 16S rRNA gene. No bias was detected on cloning and sequencing 12 housekeeping and sporulation gene fragments from amplified DNA. The detection limit by PCR with Pasteuria-specific 16S rRNA gene primers following multiple strand amplification of DNA extracted using the method was a single endospore. Generation of large quantities DNA will facilitate genomic sequencing of P. penetrans. Apparent differences in sample purity are explained by variations in 16S rRNA gene copy number in Eubacteria leading to exaggerated estimations of sample contamination. Detection of single endospores will facilitate investigations of P. penetrans molecular ecology. These methods will advance studies on P. penetrans and facilitate research on other obligate and fastidious micro-organisms where it is currently impractical to obtain DNA in sufficient quantity and quality.
Critical phenomena and chemical potential of a charged AdS black hole
NASA Astrophysics Data System (ADS)
Wei, Shao-Wen; Liang, Bin; Liu, Yu-Xiao
2017-12-01
Inspired by the interpretation of the cosmological constant from the boundary gauge theory, we here treat it as the number of colors N and its conjugate quantity as the associated chemical potential μ in the black hole side. Then the thermodynamics and the chemical potential for a five-dimensional charged AdS black hole are studied. It is found that there exists a small-large black hole phase transition of van der Waals type. The critical phenomena are investigated in the N2-μ chart. The result implies that the phase transition can occur for large number of colors N , while is forbidden for small number. This to some extent implies that the interaction of the system increases with the number. In particular, in the reduced parameter space, all the thermodynamic quantities can be rescaled with the black hole charge such that these reduced quantities are charge-independent. Then we obtain the coexistence curve and the phase diagram. The latent heat is also numerically calculated. Moreover, the heat capacity and the thermodynamic scalar are studied. The result indicates that the information of the first-order black hole phase transition is encoded in the heat capacity and scalar. However, the phase transition point cannot be directly calculated with them. Nevertheless, the critical point linked to a second-order phase transition can be determined by either the heat capacity or the scalar. In addition, we calculate the critical exponents of the heat capacity and the scalar for the saturated small and large black holes near the critical point.
Alonso, Conchita; Navarro-Fernández, Carmen M; Arceo-Gómez, Gerardo; Meindl, George A; Parra-Tabla, Víctor; Ashman, Tia-Lynn
2013-11-01
Insufficient pollination is a function of quantity and quality of pollen receipt, and the relative contribution of each to pollen limitation may vary with intrinsic plant traits and extrinsic ecological properties. Community-level studies are essential to evaluate variation across species in quality limitation under common ecological conditions. This study examined whether endemic species are more limited by pollen quantity or quality than non-endemic co-flowering species in three endemic-rich plant communities located in biodiversity hotspots of different continents (Andalusia, California and Yucatan). Natural variations in pollen receipt and pollen tube formation were analysed for 20 insect-pollinated plants. Endemic and non-endemic species that co-flowered were paired in order to estimate and compare the quantity and quality components of pre-zygotic pollination success, obtained through piecewise regression analysis of the relationship between pollen grains and pollen tubes of naturally pollinated wilted flowers. Pollen tubes did not frequently exceed the number of ovules per flower. Only the combination of abundant and good quality pollen and a low number of ovules per flower conferred relief from pre-zygotic pollen limitation in the three stochastic pollination environments studied. Quality of pollen receipt was found to be as variable as quantity among study species. The relative pollination success of endemic and non-endemic species, and its quantity and quality components, was community dependent. Assessing both quality and quantity of pollen receipt is key to determining the ovule fertilization potential of both endemic and widespread plants in biodiverse hotspot regions. Large natural variation among flowers of the same species in the two components and pollen tube formation deserves further analysis in order to estimate the environmental, phenotypic and intraindividual sources of variation that may affect how plants evolve to overcome this limitation in different communities worldwide.
UHF (Ultra-High-Frequency) Propagation in Vegetative Media.
1980-04-01
Y V /ik) where k = 2A/X is the wave number and the asterisk indicates complex conjugate. In order to obtain useful results for average values that are...easy to make an accurate estimation of the expected effects under one set of conditions on the basis of experimental observa- tions carried out under... systems propagating horizontally through vegetation. The large quantity A-13 of measured data demonstrates the complex effects upon path loss of irregu
Translations on North Korea No. 572 Kulloja, No. 11, 1977.
1978-01-25
thoroughly carry through the chuche-oriented oil production line on obtaining edible oil from corn and industrial oils from rice bran , we will be...industrial oils with rice bran . The great leader Comrade Kim Il-song taught as follows: "The question of processing corn by industrial methods is...great leader on extracting oil from corn and rice bran makes it possible within a short period of time to produce oil in large quantities everywhere
Finite size effects in the thermodynamics of a free neutral scalar field
NASA Astrophysics Data System (ADS)
Parvan, A. S.
2018-04-01
The exact analytical lattice results for the partition function of the free neutral scalar field in one spatial dimension in both the configuration and the momentum space were obtained in the framework of the path integral method. The symmetric square matrices of the bilinear forms on the vector space of fields in both configuration space and momentum space were found explicitly. The exact lattice results for the partition function were generalized to the three-dimensional spatial momentum space and the main thermodynamic quantities were derived both on the lattice and in the continuum limit. The thermodynamic properties and the finite volume corrections to the thermodynamic quantities of the free real scalar field were studied. We found that on the finite lattice the exact lattice results for the free massive neutral scalar field agree with the continuum limit only in the region of small values of temperature and volume. However, at these temperatures and volumes the continuum physical quantities for both massive and massless scalar field deviate essentially from their thermodynamic limit values and recover them only at high temperatures or/and large volumes in the thermodynamic limit.
Tong, Zhaoguo; Qu, Shenchun; Zhang, Jiyu; Wang, Fei; Tao, Jianmin; Gao, Zhihong; Zhang, Zhen
2012-03-01
RNA extraction is the first step in the study of gene isolation and expression. However, it is difficult to extract high quantity and quality RNA from tissues containing large quantities of polysaccharides and polyphenols. Peach (Prunus persica), in addition to containing high levels of polysaccharides and polyphenols, is a challenging starting material for RNA isolation using a single method because of different amounts of those substances in diverse tissues. Based on three reported methods, we developed a modified RNA isolation protocol to solve this problem, leading to high quality and quantity of total RNA from peach mesocarp tissues of fruits which were sampled from all developmental stages and different storage periods, as well as from other tissues including flowers, leaves, stems, and roots. With our modified method, 28-650 μg of total RNA was routinely obtained from per gram of fresh material, gave at least a 1.16-fold improvement by compared with those isolated by other seven methods. The RNA extracts were successfully used in downstream applications such as RT-PCR, RACE, and real-time PCR.
Growth of Foot-and-Mouth Disease Virus in Dispersed Tissue Cells
Patty, R. E.; Tozzini, F.; Seibold, H. R.; Callis, J. J.
1962-01-01
Methods are described for rapid and economical production of large quantities of foot-and-mouth disease virus in stationary cultures of trypsin-dispersed bovine kidney cells in a simple medium. Yields of between 107 and 108 plaque-forming units per milliliter were obtained from serum-free cultures containing approximately a million and a half viable trypsin-dispersed cells per milliliter. Some of the advantages and disadvantages of these methods of virus production are discussed. ImagesFig. 1Fig. 2Fig. 3 PMID:17649388
Economics in the age of big data.
Einav, Liran; Levin, Jonathan
2014-11-07
The quality and quantity of data on economic activity are expanding rapidly. Empirical research increasingly relies on newly available large-scale administrative data or private sector data that often is obtained through collaboration with private firms. Here we highlight some challenges in accessing and using these new data. We also discuss how new data sets may change the statistical methods used by economists and the types of questions posed in empirical research. Copyright © 2014, American Association for the Advancement of Science.
Data acquisition, processing and firing aid software for multichannel EMP simulation
NASA Astrophysics Data System (ADS)
Eumurian, Gregoire; Arbaud, Bruno
1986-08-01
Electromagnetic compatibility testing yields a large quantity of data for systematic analysis. An automated data acquisition system has been developed. It is based on standard EMP instrumentation which allows a pre-established program to be followed whilst orientating the measurements according to the results obtained. The system is controlled by a computer running interactive programs (multitask windows, scrollable menus, mouse, etc.) which handle the measurement channels, files, displays and process data in addition to providing an aid to firing.
Dielectric and vibrational properties of amino acids
NASA Astrophysics Data System (ADS)
Tulip, P. R.; Clark, S. J.
2004-09-01
We calculate polarizability tensors and normal mode frequencies for the amino acids alanine, leucine, isoleucine, and valine using density functional perturbation theory implemented within the plane wave pseudopotential framework. It is found that the behavior of the electron density under external fields depends to a large extent on the geometrical structure of the molecule in question, rather than simply on the constituent functional groups. The normal modes are able to help distinguish between the different types of intramolecular hydrogen bonding present, and help to explain why leucine is found in the zwitterionic form for the gaseous phase. Calculated IR spectra show a marked difference between those obtained for zwitterionic and nonzwitterionic molecules. These differences can be attributed to the different chemical and hydrogen bonds present. Effective dynamical charges are calculated, and compared to atomic charges obtained from Mulliken population analysis. It is found that disagreement exists, largely due to the differing origins of these quantities.
40 CFR 273.37 - Response to releases.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 273.37 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR UNIVERSAL WASTE MANAGEMENT Standards for Large Quantity Handlers of Universal Waste § 273.37... of universal wastes and other residues from universal wastes. (b) A large quantity handler of...
40 CFR 273.38 - Off-site shipments.
Code of Federal Regulations, 2012 CFR
2012-07-01
....38 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR UNIVERSAL WASTE MANAGEMENT Standards for Large Quantity Handlers of Universal Waste § 273.38 Off-site shipments. (a) A large quantity handler of universal waste is prohibited from sending or...
40 CFR 273.38 - Off-site shipments.
Code of Federal Regulations, 2011 CFR
2011-07-01
....38 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR UNIVERSAL WASTE MANAGEMENT Standards for Large Quantity Handlers of Universal Waste § 273.38 Off-site shipments. (a) A large quantity handler of universal waste is prohibited from sending or...
40 CFR 273.38 - Off-site shipments.
Code of Federal Regulations, 2010 CFR
2010-07-01
....38 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR UNIVERSAL WASTE MANAGEMENT Standards for Large Quantity Handlers of Universal Waste § 273.38 Off-site shipments. (a) A large quantity handler of universal waste is prohibited from sending or...
40 CFR 273.38 - Off-site shipments.
Code of Federal Regulations, 2014 CFR
2014-07-01
....38 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR UNIVERSAL WASTE MANAGEMENT Standards for Large Quantity Handlers of Universal Waste § 273.38 Off-site shipments. (a) A large quantity handler of universal waste is prohibited from sending or...
40 CFR 273.38 - Off-site shipments.
Code of Federal Regulations, 2013 CFR
2013-07-01
....38 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR UNIVERSAL WASTE MANAGEMENT Standards for Large Quantity Handlers of Universal Waste § 273.38 Off-site shipments. (a) A large quantity handler of universal waste is prohibited from sending or...
NASA Technical Reports Server (NTRS)
Righetti, Pier Giorgio; Casale, Elena; Carter, Daniel; Snyder, Robert S.; Wenisch, Elisabeth; Faupel, Michel
1990-01-01
Recombinant-DNA (deoxyribonucleic acid) (r-DNA) proteins, produced in large quantities for human consumption, are now available in sufficient amounts for crystal growth. Crystallographic analysis is the only method now available for defining the atomic arrangements within complex biological molecules and decoding, e.g., the structure of the active site. Growing protein crystals in microgravity has become an important aspect of biology in space, since crystals that are large enough and of sufficient quality to permit complete structure determinations are usually obtained. However even small amounts of impurities in a protein preparation are anathema for the growth of a regular crystal lattice. A multicompartment electrolyzer with isoelectric, immobiline membranes, able to purify large quantities of r-DNA proteins is described. The electrolyzer consists of a stack of flow cells, delimited by membranes of very precise isoelectric point (pI, consisting of polyacrylamide supported by glass fiber filters containing Immobiline buffers and titrants to uniquely define a pI value) and very high buffering power, able to titrate all proteins tangent or crossing such membranes. By properly selecting the pI values of two membranes delimiting a flow chamber, a single protein can be kept isoelectric in a single flow chamber and thus, be purified to homogeneity (by the most stringent criterion, charge homogeneity).
NASA Technical Reports Server (NTRS)
Kriegler, F.; Marshall, R.; Sternberg, S.
1976-01-01
MIDAS is a third-generation, fast, low cost, multispectral recognition system able to keep pace with the large quantity and high rates of data acquisition from large regions with present and projected sensors. MIDAS, for example, can process a complete ERTS frame in forty seconds and provide a color map of sixteen constituent categories in a few minutes. A principal objective of the MIDAS Program is to provide a system well interfaced with the human operator and thus to obtain large overall reductions in turn-around time and significant gains in throughput. The need for advanced onboard spacecraft processing of remotely sensed data is stated and approaches to this problem are described which are feasible through the use of charge coupled devices. Tentative mechanizations for the required processing operations are given in large block form. These initial designs can serve as a guide to circuit/system designers.
Method of determining whether radioactive contaminants are inside or outside a structure
Lattin, Kenneth R.
1977-01-01
A measure is obtained of the relative quantities of radioactive material inside and outside a structure such as a pipe by obtaining two spectra of gamma radiation on a dummy structure of the same shape and composition. A first spectrum is obtained with a quantity of the radioactive element to be measured located inside the structure and a second spectrum is obtained with a quantity of the same contaminant located outside the structure. The two spectra are normalized to the same equivalent value in a portion of the spectrum that does not reflect the presence of gamma rays resulting from Compton scattering in the structure. Comparison of that portion of the spectra obtained where Compton scattering is a factor gives a measure of the relative amounts of contaminants inside and outside the structure on a spectrum obtained from a test structure. The invention may also be practiced by obtaining a plurality of spectra at varying known concentrations inside and outside the dummy structure.
NASA Technical Reports Server (NTRS)
Dewitt, H. E.; Hubbard, W. B.
1976-01-01
A large quantity of data on the thermodynamic properties of hydrogen-helium metallic liquids have been obtained in extended computer calculations in which a Monte Carlo code essentially identical to that described by Hubbard (1972) was used. A model free energy for metallic hydrogen with a relatively small mass fraction of helium is discussed, taking into account the definition of variables, a procedure for choosing the free energy, values for the fitting parameters, and the evaluation of the entropy constants. Possibilities concerning a use of the obtained data in studies of the interiors of the outer planets are briefly considered.
Large-scale preparation of plasmid DNA.
Heilig, J S; Elbing, K L; Brent, R
2001-05-01
Although the need for large quantities of plasmid DNA has diminished as techniques for manipulating small quantities of DNA have improved, occasionally large amounts of high-quality plasmid DNA are desired. This unit describes the preparation of milligram quantities of highly purified plasmid DNA. The first part of the unit describes three methods for preparing crude lysates enriched in plasmid DNA from bacterial cells grown in liquid culture: alkaline lysis, boiling, and Triton lysis. The second part describes four methods for purifying plasmid DNA in such lysates away from contaminating RNA and protein: CsCl/ethidium bromide density gradient centrifugation, polyethylene glycol (PEG) precipitation, anion-exchange chromatography, and size-exclusion chromatography.
40 CFR 273.33 - Waste management.
Code of Federal Regulations, 2010 CFR
2010-07-01
... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Waste management. 273.33 Section 273...) STANDARDS FOR UNIVERSAL WASTE MANAGEMENT Standards for Large Quantity Handlers of Universal Waste § 273.33 Waste management. (a) Universal waste batteries. A large quantity handler of universal waste must manage...
Ito, Y; Zhang, T Y
1988-11-25
A preparative capability of the present cross-axis synchronous flow-through coil planet centrifuge was demonstrated with 0.5 cm I.D. multilayer coils. Results of the model studies with short coils indicated that the optimal separations are obtained at low revolutional speeds of 100-200 rpm in both central and lateral coil positions. Preparative separations were successfully performed on 2.5-10 g quantities of test samples in a pair of multilayer coils connected in series with a total capacity of 2.5 l. The sample loading capacity will be scaled up in several folds by increasing the column width.
Large scale isolation and purification of soluble RAGE from lung tissue.
Englert, Judson M; Ramsgaard, Lasse; Valnickova, Zuzana; Enghild, Jan J; Oury, Tim D
2008-09-01
The receptor for advanced glycation end-products (RAGE) has been implicated in numerous disease processes including: atherosclerosis, diabetic nephropathy, impaired wound healing and neuropathy to name a few. Treatment of animals with a soluble isoform of the receptor (sRAGE) has been shown to prevent and even reverse many disease processes. Isolating large quantities of pure sRAGE for in vitro and in vivo studies has hindered its development as a therapeutic strategy in other RAGE mediated diseases that require long-term therapy. This article provides an improvement in both yield and detail of a previously published method to obtain 10mg of pure, endotoxin free sRAGE from 65 g of lung tissue.
Miller, C.M.; Nogar, N.S.
1982-09-02
Photoionization via autoionizing atomic levels combined with conventional mass spectroscopy provides a technique for quantitative analysis of trace quantities of chemical elements in the presence of much larger amounts of other elements with substantially the same atomic mass. Ytterbium samples smaller than 10 ng have been detected using an ArF* excimer laser which provides the atomic ions for a time-of-flight mass spectrometer. Elemental selectivity of greater than 5:1 with respect to lutetium impurity has been obtained. Autoionization via a single photon process permits greater photon utilization efficiency because of its greater absorption cross section than bound-free transitions, while maintaining sufficient spectroscopic structure to allow significant photoionization selectivity between different atomic species. Separation of atomic species from others of substantially the same atomic mass is also described.
Use of bioreactors for culturing human retinal organoids improves photoreceptor yields.
Ovando-Roche, Patrick; West, Emma L; Branch, Matthew J; Sampson, Robert D; Fernando, Milan; Munro, Peter; Georgiadis, Anastasios; Rizzi, Matteo; Kloc, Magdalena; Naeem, Arifa; Ribeiro, Joana; Smith, Alexander J; Gonzalez-Cordero, Anai; Ali, Robin R
2018-06-13
The use of human pluripotent stem cell-derived retinal cells for cell therapy strategies and disease modelling relies on the ability to obtain healthy and organised retinal tissue in sufficient quantities. Generating such tissue is a lengthy process, often taking over 6 months of cell culture, and current approaches do not always generate large quantities of the major retinal cell types required. We adapted our previously described differentiation protocol to investigate the use of stirred-tank bioreactors. We used immunohistochemistry, flow cytometry and electron microscopy to characterise retinal organoids grown in standard and bioreactor culture conditions. Our analysis revealed that the use of bioreactors results in improved laminar stratification as well as an increase in the yield of photoreceptor cells bearing cilia and nascent outer-segment-like structures. Bioreactors represent a promising platform for scaling up the manufacture of retinal cells for use in disease modelling, drug screening and cell transplantation studies.
Theory based scaling of edge turbulence and implications for the scrape-off layer width
NASA Astrophysics Data System (ADS)
Myra, J. R.; Russell, D. A.; Zweben, S. J.
2016-11-01
Turbulence and plasma parameter data from the National Spherical Torus Experiment (NSTX) [Ono et al., Nucl. Fusion 40, 557 (2000)] is examined and interpreted based on various theoretical estimates. In particular, quantities of interest for assessing the role of turbulent transport on the midplane scrape-off layer heat flux width are assessed. Because most turbulence quantities exhibit large scatter and little scaling within a given operation mode, this paper focuses on length and time scales and dimensionless parameters between operational modes including Ohmic, low (L), and high (H) modes using a large NSTX edge turbulence database [Zweben et al., Nucl. Fusion 55, 093035 (2015)]. These are compared with theoretical estimates for drift and interchange rates, profile modification saturation levels, a resistive ballooning condition, and dimensionless parameters characterizing L and H mode conditions. It is argued that the underlying instability physics governing edge turbulence in different operational modes is, in fact, similar, and is consistent with curvature-driven drift ballooning. Saturation physics, however, is dependent on the operational mode. Five dimensionless parameters for drift-interchange turbulence are obtained and employed to assess the importance of turbulence in setting the scrape-off layer heat flux width λq and its scaling. An explicit proportionality of the width λq to the safety factor and major radius (qR) is obtained under these conditions. Quantitative estimates and reduced model numerical simulations suggest that the turbulence mechanism is not negligible in determining λq in NSTX, at least for high plasma current discharges.
Theory based scaling of edge turbulence and implications for the scrape-off layer width
Myra, J. R.; Russell, D. A.; Zweben, S. J.
2016-11-01
Turbulence and plasma parameter data from the National Spherical Torus Experiment (NSTX) is examined and interpreted based on various theoretical estimates. In particular, quantities of interest for assessing the role of turbulent transport on the midplane scrape-off layer heat flux width are assessed. Because most turbulence quantities exhibit large scatter and little scaling within a given operation mode, this paper focuses on length and time scales and dimensionless parameters between operational modes including Ohmic, low (L), and high (H) modes using a large NSTX edge turbulence database. These are compared with theoretical estimates for drift and interchange rates, profile modificationmore » saturation levels, a resistive ballooning condition, and dimensionless parameters characterizing L and H mode conditions. It is argued that the underlying instability physics governing edge turbulence in different operational modes is, in fact, similar, and is consistent with curvature-driven drift ballooning. Saturation physics, however, is dependent on the operational mode. Five dimensionless parameters for drift-interchange turbulence are obtained and employed to assess the importance of turbulence in setting the scrape-off layer heat flux width λ q and its scaling. An explicit proportionality of the width λ q to the safety factor and major radius (qR) is obtained under these conditions. Lastly, quantitative estimates and reduced model numerical simulations suggest that the turbulence mechanism is not negligible in determining λ q in NSTX, at least for high plasma current discharges.« less
Federal Register 2010, 2011, 2012, 2013, 2014
2010-02-01
... services for Large Quantity Generator (``LQG'') customers in the states of Kansas, Missouri, Nebraska, and...; Oklahoma City, Oklahoma; Omaha, Nebraska; and Booneville, Missouri; LQG customer contracts associated with... collection and treatment services for large quantity generator (``LQG'') customers. The resulting combination...
Frankel, Edwin; Bakhouche, Abdelhakim; Lozano-Sánchez, Jesús; Segura-Carretero, Antonio; Fernández-Gutiérrez, Alberto
2013-06-05
This review describes the olive oil production process to obtain extra virgin olive oil (EVOO) enriched in polyphenol and byproducts generated as sources of antioxidants. EVOO is obtained exclusively by mechanical and physical processes including collecting, washing, and crushing of olives, malaxation of olive paste, centrifugation, storage, and filtration. The effect of each step is discussed to minimize losses of polyphenols from large quantities of wastes. Phenolic compounds including phenolic acids, alcohols, secoiridoids, lignans, and flavonoids are characterized in olive oil mill wastewater, olive pomace, storage byproducts, and filter cake. Different industrial pilot plant processes are developed to recover phenolic compounds from olive oil byproducts with antioxidant and bioactive properties. The technological information compiled in this review will help olive oil producers to improve EVOO quality and establish new processes to obtain valuable extracts enriched in polyphenols from byproducts with food ingredient applications.
Štajner, Dubravka; Popović, Boris M.; Ćalić, Dušica; Štajner, Marijana
2014-01-01
In vivo (leaves and seed embryos) and in vitro (androgenic embryos) antioxidant scavenging activity of Aesculus hippocastanum and Aesculus flava medical plants was examined. Here we report antioxidant enzyme activities of superoxide dismutase, catalase, guaiacol peroxidase and glutathione peroxidase, reduced glutathione quantity, flavonoids, soluble protein contents, quantities of malondialdehyde, and •OH radical presence in the investigated plant samples. Total antioxidant capacity of all the samples of A. hippocastanum and A. flava was determined using FRAP, DPPH, and NO• radical scavenger capacity. The leaves of A. flava collected from the botanical garden exhibited stronger antioxidant activity (higher activities of SOD, and higher quantities of GSH, TSH, TPC, and scavenging abilities of DPPH and NO•, and higher FRAP values and lowest quantities of •OH and MDA) than in vitro obtained cultures. However, the leaves of A. flava showed higher antioxidant activity than the leaves of A. hippocastanum, and therefore they have a stronger tolerance of oxidative stress. Androgenic embryos of both species had low amount of antioxidants due to controlled in vitro environmental conditions (T, photoperiod, humidity, nutritive factors, and pathogen-free). Our results confirmed that we found optimal in vitro conditions for producing androgenic embryos of both Aesculus species. Also, we assume that horse chestnut androgenic embryos can be used as an alternative source for large-scale aescin production. PMID:24672369
Štajner, Dubravka; Popović, Boris M; Ćalić, Dušica; Št, Marijana
2014-01-01
In vivo (leaves and seed embryos) and in vitro (androgenic embryos) antioxidant scavenging activity of Aesculus hippocastanum and Aesculus flava medical plants was examined. Here we report antioxidant enzyme activities of superoxide dismutase, catalase, guaiacol peroxidase and glutathione peroxidase, reduced glutathione quantity, flavonoids, soluble protein contents, quantities of malondialdehyde, and (•)OH radical presence in the investigated plant samples. Total antioxidant capacity of all the samples of A. hippocastanum and A. flava was determined using FRAP, DPPH, and NO(•) radical scavenger capacity. The leaves of A. flava collected from the botanical garden exhibited stronger antioxidant activity (higher activities of SOD, and higher quantities of GSH, TSH, TPC, and scavenging abilities of DPPH and NO(•), and higher FRAP values and lowest quantities of (•)OH and MDA) than in vitro obtained cultures. However, the leaves of A. flava showed higher antioxidant activity than the leaves of A. hippocastanum, and therefore they have a stronger tolerance of oxidative stress. Androgenic embryos of both species had low amount of antioxidants due to controlled in vitro environmental conditions (T, photoperiod, humidity, nutritive factors, and pathogen-free). Our results confirmed that we found optimal in vitro conditions for producing androgenic embryos of both Aesculus species. Also, we assume that horse chestnut androgenic embryos can be used as an alternative source for large-scale aescin production.
Ground Water at Grant Village Site, Yellowstone National Park, Wyoming
Gordon, Ellis D.; McCullough, Richard A.; Weeks, Edwin P.
1961-01-01
On behalf of the National Park Service, the U.S. Geological Survey during the summer of 1959 made a study of ground-water conditions in the area of the Grant Village site, along the shore of the West Thumb of Yellowstone Lake, 1 to 2 miles south of the present facilities at West Thumb. The water supply for the present development at West Thumb is obtained from Duck Lake, but the quantity of water available from this source probably will be inadequate for the planned development at Grant Village. During the investigation, 11 auger holes were bored and 6 test wells were drilled. Aquifer tests by pumping and bailing methods were made at two of the test wells. All material penetrated in the auger holes and test wells is of Quaternary age except the welded tuff of possible Pliocene age that was penetrated in the lower part of test well 4. Small to moderate quantities of water were obtained from the test wells in the area. Test well 2 yielded 35 gpm (gallons per minute) at a temperature of nearly 100 deg F. Test well 6 yielded about 15 gpm at a temperature of 48 deg F. The yield of this well might be increased by perforation of additional sections of casing, followed by further development of the well. Water from the other four test wells was of inadequate quantity, too highly mineralized, or too warm to be effectively utilized. Most of the ground water sampled had high concentrations of silica and iron, and part of the water was excessively high in fluoride content. Otherwise, the ground water was of generally suitable quality for most uses. The most favorable area for obtaining water supplies from wells is near the lakeshore, where a large part of the water pumped would be ground-water flow diverted from its normal discharge into the lake. Moderate quantities of relatively cool water of fairly good quality may be available near the lakeshore between test wells 5 and 6 and immediately east of test well 6.
Energy saving by using natural energy from the shallow ground depths - many years operating results
NASA Astrophysics Data System (ADS)
Besler, Maciej; Skrzycki, Maciej; Cepiński, Wojciech
2017-11-01
We pay back more and more larger attention on solutions which saving energy produced from conventional fuels. This is possible to obtainment in significant quantities in fields in which use up the large quantities of energy. The formation the microclimate of interiors is an example of such situation. Especially in the case air conditioning, heating and mechanical ventilation. There is, however, a possibility of energy saving as well as considerable reducing the pollution coming from combustion of raw materials by utilising the natural renewable energy from the shallow ground. In the paper the results gained during several year of continuous measurement on the exchanger were presented. In summer periods an air cooling occurs 10-12 K, e. g. from +30 °C to +20 °C. In winter on the other hand, a preparatory preheating of the air is possible, e.g. from-18°C to about ± 0°C. It is then possible to obtain for the air conditioning system the total energy needed for cooling purposes at the summer periods, or up to 50% of the ventilation heat energy in winter picks.
Comonotonic bounds on the survival probabilities in the Lee-Carter model for mortality projection
NASA Astrophysics Data System (ADS)
Denuit, Michel; Dhaene, Jan
2007-06-01
In the Lee-Carter framework, future survival probabilities are random variables with an intricate distribution function. In large homogeneous portfolios of life annuities, value-at-risk or conditional tail expectation of the total yearly payout of the company are approximately equal to the corresponding quantities involving random survival probabilities. This paper aims to derive some bounds in the increasing convex (or stop-loss) sense on these random survival probabilities. These bounds are obtained with the help of comonotonic upper and lower bounds on sums of correlated random variables.
Spectroscopic diagnostics of solar flares
NASA Astrophysics Data System (ADS)
Bely-Dubau, F.; Dubau, J.; Faucher, P.; Loulergue, M.; Steenman-Clarke, L.
Observations made with the X-ray polychromator (XRP) on board the Solar Maximum Mission satellite were analyzed. Data from the bent crystal spectrometer portion of the XRP experiment, in the spectral domain 1 to 3 A, with high spectral and temporal resolution, were used. Results for the spectrum analysis of iron are given. The possibility of polarization effects is considered. Although it is demonstrated that hyperfine analyses of a given spectrum are obtainable, provided calculations include large quantities of high precision atomic data, the interpretation is limited by the hypothesis of homogeneity of the emitting plasma.
Peng, Mei; Jaeger, Sara R; Hautus, Michael J
2014-03-01
Psychometric functions are predominately used for estimating detection thresholds in vision and audition. However, the requirement of large data quantities for fitting psychometric functions (>30 replications) reduces their suitability in olfactory studies because olfactory response data are often limited (<4 replications) due to the susceptibility of human olfactory receptors to fatigue and adaptation. This article introduces a new method for fitting individual-judge psychometric functions to olfactory data obtained using the current standard protocol-American Society for Testing and Materials (ASTM) E679. The slope parameter of the individual-judge psychometric function is fixed to be the same as that of the group function; the same-shaped symmetrical sigmoid function is fitted only using the intercept. This study evaluated the proposed method by comparing it with 2 available methods. Comparison to conventional psychometric functions (fitted slope and intercept) indicated that the assumption of a fixed slope did not compromise precision of the threshold estimates. No systematic difference was obtained between the proposed method and the ASTM method in terms of group threshold estimates or threshold distributions, but there were changes in the rank, by threshold, of judges in the group. Overall, the fixed-slope psychometric function is recommended for obtaining relatively reliable individual threshold estimates when the quantity of data is limited.
Levitt, Steven D.; List, John A.; Neckermann, Susanne; Nelson, David
2016-01-01
We report on a natural field experiment on quantity discounts involving more than 14 million consumers. Implementing price reductions ranging from 9–70% for large purchases, we found remarkably little impact on revenue, either positively or negatively. There was virtually no increase in the quantity of customers making a purchase; all the observed changes occurred for customers who already were buyers. We found evidence that infrequent purchasers are more responsive to discounts than frequent purchasers. There was some evidence of habit formation when prices returned to pre-experiment levels. There also was some evidence that consumers contemplating small purchases are discouraged by the presence of extreme quantity discounts for large purchases. PMID:27382146
Lie-Mei symmetry and conserved quantities of the Rosenberg problem
NASA Astrophysics Data System (ADS)
Liu, Xiao-Wei; Li, Yuan-Cheng
2011-07-01
The Rosenberg problem is a typical but not too complicated problem of nonholonomic mechanical systems. The Lie—Mei symmetry and the conserved quantities of the Rosenberg problem are studied. For the Rosenberg problem, the Lie and the Mei symmetries for the equation are obtained, the conserved quantities are deduced from them and then the definition and the criterion for the Lie—Mei symmetry of the Rosenberg problem are derived. Finally, the Hojman conserved quantity and the Mei conserved quantity are deduced from the Lie—Mei symmetry.
Comparison between two methods of scorpion venom milking in Morocco
2013-01-01
Background The present study compared two methods used successfully in a large-scale program for the collection of scorpion venoms, namely the milking of adult scorpions via manual and electrical stimulation. Results Our immunobiochemical characterizations clearly demonstrate that regularly applied electrical stimulation obtains scorpion venom more easily and, most importantly, in greater quantity. Qualitatively, the electrically collected venom showed lack of hemolymph contaminants such as hemocyanin. In contrast, manual obtainment of venom subjects scorpions to maximal trauma, leading to hemocyanin secretion. Our study highlighted the importance of reducing scorpion trauma during venom milking. Conclusions In conclusion, to produce high quality antivenom with specific antibodies, it is necessary to collect venom by the gentler electrical stimulation method. PMID:23849043
Growing Large Quantities of Containerized Seedlings
Tim Pittman
2002-01-01
The sowing of large quantities of longleaf pine (Pinus palustris Mill.) seed into trays depends on the quality of the seed and the timing of seed sowing. This can be accomplished with mechanization. Seed quality is accomplished by using a gravity table. Tray filling can be accomplished by using a ribbon-type soil mixer and an automated tray-filling...
USDA-ARS?s Scientific Manuscript database
Lunasin is a 5-kDa soybean bioactive peptide with demonstrated anti-cancer and anti-inflammatory properties. The use of lunasin as a chemopreventive agent in large-scale animal studies and human clinical trials is hampered by the paucity of large quantities of lunasin. Recently, purification methods...
VizieR Online Data Catalog: Tully-Fisher relation for SDSS galaxies (Reyes+, 2011)
NASA Astrophysics Data System (ADS)
Reyes, R.; Mandelbaum, R.; Gunn, J. E.; Pizagno, J.; Lackner, C. N.
2012-05-01
In this paper, we derive scaling relations between photometric observable quantities and disc galaxy rotation velocity Vrot or Tully-Fisher relations (TFRs). Our methodology is dictated by our purpose of obtaining purely photometric, minimal-scatter estimators of Vrot applicable to large galaxy samples from imaging surveys. To achieve this goal, we have constructed a sample of 189 disc galaxies at redshifts z<0.1 with long-slit Hα spectroscopy from Pizagno et al. (2007, Cat. J/AJ/134/945) and new observations. By construction, this sample is a fair subsample of a large, well-defined parent disc sample of ~170000 galaxies selected from the Sloan Digital Sky Survey Data Release 7 (SDSS DR7). (4 data files).
Formation of Nanodimensional 3C-SiC Structures from Rice Husks
NASA Astrophysics Data System (ADS)
Gorzkowski, E. P.; Qadri, S. B.; Rath, B. B.; Goswami, R.; Caldwell, J. D.
2013-05-01
We have demonstrated that large quantities of β-SiC nanostructures can be obtained from rice husk agricultural waste by using controlled conditions in a thermogravimetric setup. This simple and inexpensive method of producing these structures on a large scale is critical for applications in nanoelectronics, nanosensors, and biotechnology. The temperature and atmosphere are two critical elements in forming either α-cristobalite (SiO2) or β-SiC. Using different characterization methods (x-ray diffraction, scanning electron microscopy, transmission electron microscopy, and Raman spectroscopy), we have shown that pyrolysis of rice husks in argon atmosphere at 1375°C results in simultaneous formation of carbon nanotubes, β-SiC nanowires/nanorods, and β-SiC powder.
NASA Astrophysics Data System (ADS)
Santos, Marlus Alves Dos; Teixeira, Francesco Brugnera; Moreira, Heline Hellen Teixeira; Rodrigues, Adele Aud; Machado, Fabrício Castro; Clemente, Tatiana Mordente; Brigido, Paula Cristina; Silva, Rebecca Tavares E.; Purcino, Cecílio; Gomes, Rafael Gonçalves Barbosa; Bahia, Diana; Mortara, Renato Arruda; Munte, Claudia Elisabeth; Horjales, Eduardo; da Silva, Claudio Vieira
2014-03-01
Structural studies of proteins normally require large quantities of pure material that can only be obtained through heterologous expression systems and recombinant technique. In these procedures, large amounts of expressed protein are often found in the insoluble fraction, making protein purification from the soluble fraction inefficient, laborious, and costly. Usually, protein refolding is avoided due to a lack of experimental assays that can validate correct folding and that can compare the conformational population to that of the soluble fraction. Herein, we propose a validation method using simple and rapid 1D 1H nuclear magnetic resonance (NMR) spectra that can efficiently compare protein samples, including individual information of the environment of each proton in the structure.
Wilkins, Chris; Sweetsur, Paul; Girling, Melissa
2008-11-01
A large legal market for party pills containing benzylpiperazine (BZP) and trifluoromethylphenylpiperazine (TFMPP) developed in New Zealand after 2004. The use of these party pills has been associated with adverse health effects. The purpose of this paper was to assess a general population sample of party pill users to investigate the relationship between (1) patterns of use of BZP/TFMPP party pills and concurrent use of other drug types, and (2) adverse side effects from BZP/TFMPP party pill use. A national household survey of the use of BZP/TFMPP party pills was conducted using a computer-assisted telephone interviewing (CATI) facility. The quantity of BZP and TFMPP in each brand of party pill was obtained from the National Poisons Centre. Multiple logistic regression analysis was used to identify independent predictors of having experienced adverse side effects from party pills. The mean quantity of BZP/TFMPP taken on an occasion of greatest use was 533 mg (median 400 mg, range 43-2500 mg). Being female, using cannabis and other drugs concurrently with BZP/TFMPP party pills, taking large quantities of party pills in a single session and taking 5-hydroxytryptophan (5-HTP) recovery pills at the same time as party pills were independent predictors of having experienced an adverse problem from party pills. Females may be at greater risk of experiencing problems from BZP/TFMPP party pills due to their smaller physical size. Taking 5-HTP 'recovery' pills with party pills may increase the risk of adverse effects as both substances increase users' levels of serotonin.
Polymer Nanosheet Containing Star-Like Copolymers: A Novel Scalable Controlled Release System.
Cao, Peng-Fei; de Leon, Al; Rong, Lihan; Yin, Ke-Zhen; Abenojar, Eric C; Su, Zhe; Tiu, Brylee David B; Exner, Agata A; Baer, Eric; Advincula, Rigoberto C
2018-04-26
Poly(ε-caprolactone) (PCL)-based nanomaterials, such as nanoparticles and liposomes, have exhibited great potential as controlled release systems, but the difficulties in large-scale fabrication limit their practical applications. Among the various methods being developed to fabricate polymer nanosheets (PNSs) for different applications, such as Langmuir-Blodgett technique and layer-by-layer assembly, are very effort consuming, and only a few PNSs can be obtained. In this paper, poly(ε-caprolactone)-based PNSs with adjustable thickness are obtained in large quantity by simple water exposure of multilayer polymer films, which are fabricated via a layer multiplying coextrusion method. The PNS is also demonstrated as a novel controlled guest release system, in which release kinetics are adjustable by the nanosheet thickness, pH values of the media, and the presence of protecting layers. Theoretical simulations, including Korsmeyer-Peppas model and Finite-element analysis, are also employed to discern the observed guest-release mechanisms. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Biennial Hazardous Waste Report
Federal regulations require large quantity generators to submit a report (EPA form 8700-13A/B) every two years regarding the nature, quantities and disposition of hazardous waste generated at their facility.
CO2 microbubble contrast enhancement in x-ray angiography.
Kariya, S; Komemushi, A; Nakatani, M; Yoshida, R; Sawada, S; Tanigawa, N
2013-04-01
To demonstrate that carbon dioxide (CO2) microbubble contrast enhancement depicts blood vessels when used for x-ray examinations. Microbubbles were generated by cavitation of physiological saline to which CO2 gas had been added using an ejector-type microbubble generator. The input pressure values for CO2 gas and physiological saline that produced a large quantity of CO2 microbubbles were obtained in a phantom. In an animal study, angiography was performed in three swine using three types of contrast: CO2 microbubbles, conventional CO2 gas, and iodinated contrast medium. For CO2 microbubble contrast enhancement, physiological saline, and CO2 gas were supplied at the input pressures calculated in the phantom experiment. Regions of interest were set in the abdominal aorta, external iliac arteries, and background. The difference in digital values between each artery and the background was calculated. The input pressures obtained in the phantom experiment were 0.16 MPa for physiological saline and 0.5 MPa for CO2 gas, with physiological saline input volume being 8.1 ml/s. Three interventional radiologists all evaluated the depictions of all arteries as "present" in the CO2 microbubble contrast enhancement, conventional CO2 contrast enhancement, and iodinated contrast enhancement performed in three swine. Digital values for all vessels with microbubble CO2 contrast enhancement were higher than background values. In x-ray angiography, blood vessels can be depicted by CO2 microbubble contrast enhancement, in which a large quantity of CO2 microbubbles is generated within blood vessels. Copyright © 2012 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.
14 CFR 29.1553 - Fuel quantity indicator.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Placards § 29.1553 Fuel quantity indicator. If the unusable fuel supply for any tank exceeds one gallon, or... extending from the calibrated zero reading to the lowest reading obtainable in level flight. ...
14 CFR 25.1553 - Fuel quantity indicator.
Code of Federal Regulations, 2010 CFR
2010-01-01
... Placards § 25.1553 Fuel quantity indicator. If the unusable fuel supply for any tank exceeds one gallon, or... extending from the calibrated zero reading to the lowest reading obtainable in level flight. ...
Discovery of Newer Therapeutic Leads for Prostate Cancer
2009-06-01
promising plant extracts and then prepare large-scale quantities of the plant extracts using supercritical fluid extraction techniques and use this...quantities of the plant extracts using supercritical fluid extraction techniques. Large scale plant collections were conducted for 14 of the top 20...material for bioassay-guided fractionation of the biologically active constituents using modern chromatography techniques. The chemical structures of
Henderson, Timothy M.; Wuttke, Gilbert H.
1977-01-01
A variable leak gas source and a method for obtaining the same which includes filling a quantity of hollow glass micro-spheres with a gas, storing said quantity in a confined chamber having a controllable outlet, heating said chamber above room temperature, and controlling the temperature of said chamber to control the quantity of gas passing out of said controllable outlet. Individual gas filled spheres may be utilized for calibration purposes by breaking a sphere having a known quantity of a known gas to calibrate a gas detection apparatus.
Calculation and analysis of velocity and viscous drag in an artery with a periodic pressure gradient
NASA Astrophysics Data System (ADS)
Alizadeh, M.; Seyedpour, S. M.; Mozafari, V.; Babazadeh, Shayan S.
2012-07-01
Blood as a fluid that human and other living creatures are dependent on has been always considered by scientists and researchers. Any changes in blood pressure and its normal velocity can be a sign of a disease. Whatever significant in blood fluid's mechanics is Constitutive equations and finding some relations for analysis and description of drag, velocity and periodic blood pressure in vessels. In this paper, by considering available experimental quantities, for blood pressure and velocity in periodic time of a thigh artery of a living dog, at first it is written into Fourier series, then by solving Navier-Stokes equations, a relation for curve drawing of vessel blood pressure with rigid wall is obtained. Likewise in another part of this paper, vessel wall is taken in to consideration that vessel wall is elastic and its pressure and velocity are written into complex Fourier series. In this case, by solving Navier-Stokes equations, some relations for blood velocity, viscous drag on vessel wall and blood pressure are obtained. In this study by noting that vessel diameter is almost is large (3.7 mm), and blood is considered as a Newtonian fluid. Finally, available experimental quantities of pressure with obtained curve of solving Navier-Stokes equations are compared. In blood analysis in rigid vessel, existence of 48% variance in pressure curve systole peak caused vessel blood flow analysis with elastic wall, results in new relations for blood flow description. The Resultant curve is obtained from new relations holding 10% variance in systole peak.
Quantity Representation in Children and Rhesus Monkeys: Linear Versus Logarithmic Scales
ERIC Educational Resources Information Center
Beran, Michael J.; Johnson-Pynn, Julie S.; Ready, Christopher
2008-01-01
The performances of 4- and 5-year-olds and rhesus monkeys were compared using a computerized task for quantity assessment. Participants first learned two quantity anchor values and then responded to intermediate values by classifying them as similar to either the large anchor or the small anchor. Of primary interest was an assessment of where the…
NASA Astrophysics Data System (ADS)
Miyazaki, Jun
2013-10-01
We present an analytical method for quantifying exciton hopping in an energetically disordered system with quenching sites. The method is subsequently used to provide a quantitative understanding of exciton hopping in a quantum dot (QD) array. Several statistical quantities that characterize the dynamics (survival probability, average number of distinct sites visited, average hopping distance, and average hopping rate in the initial stage) are obtained experimentally by measuring time-resolved fluorescence intensities at various temperatures. The time evolution of these quantities suggests in a quantitative way that at low temperature an exciton tends to be trapped at a local low-energy site, while at room temperature, exciton hopping occurs repeatedly, leading to a large hopping distance. This method will serve to facilitate highly efficient optoelectronic devices using QDs such as photovoltaic cells and light-emitting diodes, since exciton hopping is considered to strongly influence their operational parameters. The presence of a dark QD (quenching site) that exhibits fast decay is also quantified.
Experimental models for studying mucociliary clearance.
King, M
1998-01-01
Respiratory tract mucus is a viscoelastic gel, the rheological properties of which are determined mainly by its content of mucous glycoproteins and water. The rheology and quantity of mucus, in concert with ciliary factors, are the major determinants of mucociliary clearance. A wide range of animal models for studying the secretion and clearance of mucus are available. Ex vivo models, such as the frog palate or excised bovine trachea, provide direct, meaningful data regarding the clearability of mucus. Rodent models of chronic bronchitis, based on irritant gas or cigarette smoke exposure, show important features of the human condition in a relatively short time. The rheological characterization of mucus is made difficult by the small quantities obtainable, particularly from normal animals. Large animal models, such as the dog or sheep, although more expensive, offer many advantages, such as the ability to carry out long-term serial measurements, and to make integrated measurements of the clearance of mucus, ciliary function, epithelial ion transport, and the rheology of mucus in the same preparation.
Self-Taught Learning Based on Sparse Autoencoder for E-Nose in Wound Infection Detection
He, Peilin; Jia, Pengfei; Qiao, Siqi; Duan, Shukai
2017-01-01
For an electronic nose (E-nose) in wound infection distinguishing, traditional learning methods have always needed large quantities of labeled wound infection samples, which are both limited and expensive; thus, we introduce self-taught learning combined with sparse autoencoder and radial basis function (RBF) into the field. Self-taught learning is a kind of transfer learning that can transfer knowledge from other fields to target fields, can solve such problems that labeled data (target fields) and unlabeled data (other fields) do not share the same class labels, even if they are from entirely different distribution. In our paper, we obtain numerous cheap unlabeled pollutant gas samples (benzene, formaldehyde, acetone and ethylalcohol); however, labeled wound infection samples are hard to gain. Thus, we pose self-taught learning to utilize these gas samples, obtaining a basis vector θ. Then, using the basis vector θ, we reconstruct the new representation of wound infection samples under sparsity constraint, which is the input of classifiers. We compare RBF with partial least squares discriminant analysis (PLSDA), and reach a conclusion that the performance of RBF is superior to others. We also change the dimension of our data set and the quantity of unlabeled data to search the input matrix that produces the highest accuracy. PMID:28991154
Erny, Guillaume L; Gonçalves, Bruna M; Esteves, Valdemar I
2013-09-06
In this work, humic substances (HS) immobilized, as a thin layer or as aggregates, on silica gel were tested as material for solid phase extraction. Some triazines (simazine, atrazine, therbutylazine, atrazine-desethyl-desisopropyl-2-hydroxy, ametryn and terbutryn), have been selected as test analytes due to their environmental importance and to span a large range of solubility and octanol/water partition coefficient (logP). The sorbent was obtained immobilizing a thin layer of HS via physisorption on a pre-coated silica gel with a cationic polymer (polybrene). While the sorbent could be used as it is, it was demonstrated that additional HS could be immobilized, via weak interactions, to form stable humic aggregates. However, while a higher quantity of HS could be immobilized, no significant differences were observed in the sorption parameters. This sorbent have been tested for solid phase extraction to concentrate triazines from aqueous matrixes. The sorbent demonstrated performances equivalent to commercial alternatives as a concentration factor between 50 and 200, depending on the type of triazines, was obtained. Moreover the low cost and the high flow rate of sample through the column allowed using high quantity of sorbent. The analytical procedure was tested with different matrixes including tap water, river water and estuarine water. Copyright © 2013 Elsevier B.V. All rights reserved.
Cell Expansion During Directed Differentiation of Stem Cells Toward the Hepatic Lineage.
Raju, Ravali; Chau, David; Cho, Dong Seong; Park, Yonsil; Verfaillie, Catherine M; Hu, Wei-Shou
2017-02-15
The differentiation of human pluripotent stem cells toward the hepatocyte lineage can potentially provide an unlimited source of functional hepatocytes for transplantation and extracorporeal bioartificial liver applications. It is anticipated that the quantities of cells needed for these applications will be in the order of 10 9 -10 10 cells, because of the size of the liver. An ideal differentiation protocol would be to enable directed differentiation to the hepatocyte lineage with simultaneous cell expansion. We introduced a cell expansion stage after the commitment of human embryonic stem cells to the endodermal lineage, to allow for at least an eightfold increase in cell number, with continuation of cell maturation toward the hepatocyte lineage. The progressive changes in the transcriptome were measured by expression array, and the expression dynamics of certain lineage markers was measured by mass cytometry during the differentiation and expansion process. The findings revealed that while cells were expanding they were also capable of progressing in their differentiation toward the hepatocyte lineage. In addition, our transcriptome, protein and functional studies, including albumin secretion, drug-induced CYP450 expression and urea production, all indicated that the hepatocyte-like cells obtained with or without cell expansion are very similar. This method of simultaneous cell expansion and hepatocyte differentiation should facilitate obtaining large quantities of cells for liver cell applications.
Mousavi, Seyed Mohsen; Niaki, S. T. A.; Bahreininejad, Ardeshir; Musa, Siti Nurmaya
2014-01-01
A multi-item multiperiod inventory control model is developed for known-deterministic variable demands under limited available budget. Assuming the order quantity is more than the shortage quantity in each period, the shortage in combination of backorder and lost sale is considered. The orders are placed in batch sizes and the decision variables are assumed integer. Moreover, all unit discounts for a number of products and incremental quantity discount for some other items are considered. While the objectives are to minimize both the total inventory cost and the required storage space, the model is formulated into a fuzzy multicriteria decision making (FMCDM) framework and is shown to be a mixed integer nonlinear programming type. In order to solve the model, a multiobjective particle swarm optimization (MOPSO) approach is applied. A set of compromise solution including optimum and near optimum ones via MOPSO has been derived for some numerical illustration, where the results are compared with those obtained using a weighting approach. To assess the efficiency of the proposed MOPSO, the model is solved using multi-objective genetic algorithm (MOGA) as well. A large number of numerical examples are generated at the end, where graphical and statistical approaches show more efficiency of MOPSO compared with MOGA. PMID:25093195
Potential of derived lunar volatiles for life support
NASA Technical Reports Server (NTRS)
Bula, R. J.; Wittenberg, L. J.; Tibbitts, T. W.; Kulcinski, G. L.
1992-01-01
The lunar regolith contains small quantities of solar wind implanted volatile compounds that have vital, basic uses for maintaining life support systems of lunar or space settlements. Recent proposals to utilize the helium-3 isotope (He-3) derived from the lunar regolith as a fuel for fusion reactors would result in the availability of large quantities of other lunar volatile compounds. The quantities obtained would provide the annual life support replacement requirements of 1150 to 23,000 inhabitants per ton of He-3 recovered, depending on the volatile compound. Utilization of the lunar volatile compounds for life support depends on the costs, in terms of materials and energy, associated with their extraction from the lunar regolith as compared to the delivery costs of these compounds from Earth resources. Considering today's conservative estimated transportation costs ($10,000 dollars per kilogram) and regolith mining costs ($5 dollars per ton), the life support replacement requirements could be more economically supplied by recovering the lunar volatile compounds than transporting these materials from Earth resources, even before He-3 will be utilized as a fusion fuel. In addition, availability of lunar volatile compounds could have a significant cost impact on maintaining the life support systems of the space station and a Mars base.
Hernández-Osorio, L A; Márquez-Dueñas, C; Florencio-Martínez, L E; Ballesteros-Rodea, G; Martínez-Calvillo, S; Manning-Cela, R G
2010-01-01
Trypanosoma cruzi undergoes a biphasic life cycle that consists of four alternate developmental stages. In vitro conditions to obtain a synchronic transformation and efficient rates of pure intermediate forms (IFs), which are indispensable for further biochemical, biological, and molecular studies, have not been reported. In the present study, we established an improved method to obtain IFs from secondary amastigogenesis. During the transformation kinetics, we observed progressive decreases in the size of the parasite body, undulating membrane and flagellum that were concomitant with nucleus remodeling and kinetoplast displacement. In addition, a gradual reduction in parasite movement and acquisition of the amastigote-specific Ssp4 antigen were observed. Therefore, our results showed that the in vitro conditions used obtained large quantities of highly synchronous and pure IFs that were clearly distinguished by morphometrical and molecular analyses. Obtaining these IFs represents the first step towards an understanding of the molecular mechanisms involved in amastigogenesis.
NASA Technical Reports Server (NTRS)
Squires, Kyle D.; Eaton, John K.
1991-01-01
Direct numerical simulation is used to study dispersion in decaying isotropic turbulence and homogeneous shear flow. Both Lagrangian and Eulerian data are presented allowing direct comparison, but at fairly low Reynolds number. The quantities presented include properties of the dispersion tensor, isoprobability contours of particle displacement, Lagrangian and Eulerian velocity autocorrelations and time scale ratios, and the eddy diffusivity tensor. The Lagrangian time microscale is found to be consistently larger than the Eulerian microscale, presumably due to the advection of the small scales by the large scales in the Eulerian reference frame.
NASA Technical Reports Server (NTRS)
Mccutchen, D. K.; Brose, J. F.; Palm, W. E.
1982-01-01
One nemesis of the structural dynamist is the tedious task of reviewing large quantities of data. This data, obtained from various types of instrumentation, may be represented by oscillogram records, root-mean-squared (rms) time histories, power spectral densities, shock spectra, 1/3 octave band analyses, and various statistical distributions. In an attempt to reduce the laborious task of manually reviewing all of the space shuttle orbiter wideband frequency-modulated (FM) analog data, an automated processing system was developed to perform the screening process based upon predefined or predicted threshold criteria.
Morreale, A C; Novog, D R; Luxat, J C
2012-01-01
Technetium-99m is an important medical isotope utilized worldwide in nuclear medicine and is produced from the decay of its parent isotope, molybdenum-99. The online fueling capability and compact fuel of the CANDU(®)(1) reactor allows for the potential production of large quantities of (99)Mo. This paper proposes (99)Mo production strategies using modified target fuel bundles loaded into CANDU fuel channels. Using a small group of channels a yield of 89-113% of the weekly world demand for (99)Mo can be obtained. Copyright © 2011 Elsevier Ltd. All rights reserved.
NASA Astrophysics Data System (ADS)
Diggs, Angela; Balachandar, Sivaramakrishnan
2015-06-01
The present work addresses the numerical methods required for particle-gas and particle-particle interactions in Eulerian-Lagrangian simulations of multiphase flow. Local volume fraction as seen by each particle is the quantity of foremost importance in modeling and evaluating such interactions. We consider a general multiphase flow with a distribution of particles inside a fluid flow discretized on an Eulerian grid. Particle volume fraction is needed both as a Lagrangian quantity associated with each particle and also as an Eulerian quantity associated with the flow. In Eulerian Projection (EP) methods, the volume fraction is first obtained within each cell as an Eulerian quantity and then interpolated to each particle. In Lagrangian Projection (LP) methods, the particle volume fraction is obtained at each particle and then projected onto the Eulerian grid. Traditionally, EP methods are used in multiphase flow, but sub-grid resolution can be obtained through use of LP methods. By evaluating the total error and its components we compare the performance of EP and LP methods. The standard von Neumann error analysis technique has been adapted for rigorous evaluation of rate of convergence. The methods presented can be extended to obtain accurate field representations of other Lagrangian quantities. Most importantly, we will show that such careful attention to numerical methodologies is needed in order to capture complex shock interaction with a bed of particles. Supported by U.S. Department of Defense SMART Program and the U.S. Department of Energy PSAAP-II program under Contract No. DE-NA0002378.
Ground-water resources and geology of northern and central Johnson County, Wyoming
Whitcomb, Harold A.; Cummings, T. Ray; McCullough, Richard A.
1966-01-01
Northern and central Johnson County, Wyo., is an area of about 2,600 square miles that lies principally in the western part of the Powder River structural basin but also includes the east flank of the Bighorn Mountains. Sedimentary rocks exposed range in age from Cambrian to Recent and have an average total thickness of about 16,000 feet. Igneous and metamorphic rocks of Precambrian age crop out in the Bighorn Mountains. Rocks of pre-Tertiary age, exposed on the flanks and in the foothills of the Bighorns, dip steeply eastward and lie at great depth in the Powder River basin. The rest of the project area is underlain by a thick sequence of interbedded sandstone, siltstone, and shale of Paleocene and Eocene age. Owing to the regional structure, most aquifers in Johnson County contain water under artesian pressure. The Madison Limestone had not been tapped for water in Johnson County at the time of the present investigation (1963), but several wells in eastern Big Horn and Washakie Counties, on the west flank of the Bighorn Mountains, reportedly have flows ranging from 1,100 to 2,800 gallons per minute. Comparable yields can probably be obtained from the Madison in Johnson County in those areas where the limestone is fractured or cavernous. The Tensleep Sandstone reportedly yields 600 gallons per minute to a pumped irrigation well near its outcrop in the southwestern part of the project area. Several flowing wells tap the formation on the west flank of the Bighorn Mountains. The Madison Limestone and the Tensleep Sandstone have limited potential as sources of water because they can be developed economically only in a narrow band paralleling the Bighorn Mountain front in the southwestern part of the project area. Overlying the Tensleep Sandstone is about 6,000 feet of shale, siltstone, and fine-grained sandstone that, with a few exceptions, normally yields only small quantities of water to wells. The Cloverly Formation and the Newcastle Sandstone may yield moderate quantities of water to wells; but, in some areas, properly constructed wells tapping both formations might yield large quantities of water. The Shannon Sandstone Member of the Cody Shale will probably yield only small quantities of water to Wells, but it is the best potential source of ground water in the stratigraphic interval between the Newcastle and Parkman Sandstones. The Parkman Sandstone and the Lance Formation yield water to relatively shallow wells principally in the southwestern part of the project area. The Fort Union Formation yields adequate supplies of water for stock and domestic use from relatively shallow wells near its outcrop almost everywhere in the county. A few deep wells tap the Fort Union along the Powder River valley in the northeastern part of Johnson County. Some of these wells flow, but their flows rarely exceed 10 gallons per minute; larger yields could be undoubtedly be obtained by pumping. The Wasatch Formation is the principal source of ground water in Johnson County. It yields adequate supplies to many relatively shallow stock and domestic wells, some of which flow, but much larger yields probably would require pumping lifts that are prohibitive for most purposes. The Kingsbury Conglomerate and Moncrief Members of the Wasatch Formation, though, may yield moderate quantities of water in some places. Alluvial deposits underlying the valleys of the Powder River and Crazy Woman, Clear, and Piney Creeks are potential sources of moderate to large supplies of water in the Powder River drainage basin. The permeability of these deposits decreases with distance from the Bighorn Mountain front, so that largest yields can probably be obtained along the upper reaches of these streams. Most ground water utilized in the project area is for domestic and stock supplies and is obtained from drilled wells and from springs. Water for irrigation is obtained almost entirely by diverting flows of perennial streams. The discharge of wel
NASA Technical Reports Server (NTRS)
Turner, J. W. (Inventor)
1973-01-01
A measurement system is described for providing an indication of a varying physical quantity represented by or converted to a variable frequency signal. Timing pulses are obtained marking the duration of a fixed number, or set, of cycles of the sampled signal and these timing pulses are employed to control the period of counting of cycles of a higher fixed and known frequency source. The counts of cycles obtained from the fixed frequency source provide a precise measurement of the average frequency of each set of cycles sampled, and thus successive discrete values of the quantity being measured. The frequency of the known frequency source is made such that each measurement is presented as a direct digital representation of the quantity measured.
Large-Eddy Simulation of Turbulent Wall-Pressure Fluctuations
NASA Technical Reports Server (NTRS)
Singer, Bart A.
1996-01-01
Large-eddy simulations of a turbulent boundary layer with Reynolds number based on displacement thickness equal to 3500 were performed with two grid resolutions. The computations were continued for sufficient time to obtain frequency spectra with resolved frequencies that correspond to the most important structural frequencies on an aircraft fuselage. The turbulent stresses were adequately resolved with both resolutions. Detailed quantitative analysis of a variety of statistical quantities associated with the wall-pressure fluctuations revealed similar behavior for both simulations. The primary differences were associated with the lack of resolution of the high-frequency data in the coarse-grid calculation and the increased jitter (due to the lack of multiple realizations for averaging purposes) in the fine-grid calculation. A new curve fit was introduced to represent the spanwise coherence of the cross-spectral density.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Perkins, R. J., E-mail: rperkins@pppl.gov; Bellan, P. M.
Action integrals are often used to average a system over fast oscillations and obtain reduced dynamics. It is not surprising, then, that action integrals play a central role in the Hellmann-Feynman theorem of classical mechanics, which furnishes the values of certain quantities averaged over one period of rapid oscillation. This paper revisits the classical Hellmann-Feynman theorem, rederiving it in connection to an analogous theorem involving the time-averaged evolution of canonical coordinates. We then apply a modified version of the Hellmann-Feynman theorem to obtain a new result: the magnetic flux enclosed by one period of gyro-motion of a charged particle inmore » a non-uniform magnetic field. These results further demonstrate the utility of the action integral in regards to obtaining orbit-averaged quantities and the usefulness of this formalism in characterizing charged particle motion.« less
Nagle, J F; Wiener, M C
1989-01-01
Three relations are derived that connect low angle diffraction/scattering results obtained from lipid bilayers to other structural quantities of interest. The first relates the area along the surface of the bilayer, the measured specific volume, and the zeroth order structure factor, F(0). The second relates the size of the trough in the center of the electron density profile, the volume of the terminal methyl groups, and the volume of the methylene groups in the fatty acid chains. The third relates the size of the headgroup electron density peak, the volume of the headgroup, and the volumes of water and hydrocarbon in the headgroup region. These relations, which are easily modified for neutron diffraction, are useful for obtaining structural quantities from electron density profiles obtained by fitting model profiles to measured low angle x-ray intensities. PMID:2713444
MANAGEMENT OF HOUSEHOLD AND SMALL-QUANTITY-GENERATOR HAZARDOUS WASTE IN THE UNITED STATES
The International Solid Waste and Public Cleansing Association (ISWA), an international nongovernmental organization comprising twenty-seven national organizations of waste management professionals, conducted a survey to obtain information regarding household and small-quantity-g...
An efficient method for the fusion of light field refocused images
NASA Astrophysics Data System (ADS)
Wang, Yingqian; Yang, Jungang; Xiao, Chao; An, Wei
2018-04-01
Light field cameras have drawn much attention due to the advantage of post-capture adjustments such as refocusing after exposure. The depth of field in refocused images is always shallow because of the large equivalent aperture. As a result, a large number of multi-focus images are obtained and an all-in-focus image is demanded. Consider that most multi-focus image fusion algorithms do not particularly aim at large numbers of source images and traditional DWT-based fusion approach has serious problems in dealing with lots of multi-focus images, causing color distortion and ringing effect. To solve this problem, this paper proposes an efficient multi-focus image fusion method based on stationary wavelet transform (SWT), which can deal with a large quantity of multi-focus images with shallow depth of fields. We compare SWT-based approach with DWT-based approach on various occasions. And the results demonstrate that the proposed method performs much better both visually and quantitatively.
ERIC Educational Resources Information Center
Cheema, Jehanzeb R.; Zhang, Bo
2013-01-01
This study looked at the effect of both quantity and quality of computer use on achievement. The Program for International Student Assessment (PISA) 2003 student survey comprising of 4,356 students (boys, n = 2,129; girls, n = 2,227) was used to predict academic achievement from quantity and quality of computer use while controlling for…
Conformal invariance and conserved quantities of mechanical system with unilateral constraints
NASA Astrophysics Data System (ADS)
Wang, Peng
2018-06-01
By distinguishing the different constraint cases, the whole course and piecewise conserved quantities, which deduced from conformal invariance of mechanical systems with unilateral constraints, are given. The determining equation of conformal invariance of the system is obtained. The sufficient and necessary conditions for the conformal invariance must be Lie symmetry of the system are given. The forms of conformal factors are obtained. An example is given to illustrate the results in this paper.
Sun, Chenjing; Zhang, Hongliang; Xu, Jiang; Gao, Jie
2013-01-01
Introduction Human myasthenia gravis (MG) is an autoimmune disorder of the neuromuscular system. Experimental autoimmune myasthenia gravis (EAMG) is a well-established animal model for MG that can be induced by active immunization with the Torpedo californica-derived acetylcholine receptor (AChR). Due to the expensive cost of purifying AChR from Torpedo californica, the development of an easier and more economical way of inducing EAMG remains critically needed. Material and methods Full-length cDNA of the human skeletal muscle AChR α1 subunit was obtained from TE671 cells. The DNA fragment encoding the extracellular domain (ECD) was then amplified by polymerase chain reaction (PCR) and inserted into pET-16b. The reconstructed plasmid was transformed into the host strain BL21(DE3)pLysS, which was derived from Escherichia coli. Isopropyl-β-D-thiogalactopyranoside (IPTG) was used to induce the expression of the N-terminal ECD. The produced protein was purified with immobilized Ni2+ affinity chromatography and refolded by dialysis. Results The recombinant protein was efficiently refolded to soluble active protein, which was verified by ELISA. After immunization with the recombinant ECD, all rats acquired clinical signs of EAMG. The titer of AChR antibodies in the serum was significantly higher in the EAMG group than in the control group, indicating successful induction of EAMG. Conclusions We describe an improved procedure for refolding recombinant ECD of human muscle AChR. This improvement allows for the generation of large quantities of correctly folded recombinant ECD of human muscle AChR, which provides for an easier and more economical way of inducing the animal model of MG. PMID:24904677
Avula, Bharathi; Chittiboyina, Amar G; Sagi, Satyanarayanaraju; Wang, Yan-Hong; Wang, Mei; Khan, Ikhlas A; Cohen, Pieter A
2016-01-01
Vinpocetine and picamilon are drugs prescribed in many countries to treat a variety of cerebrovascular disorders. In the United States, vinpocetine and picamilon have never been approved by the US Food and Drug Administration, but they are both available for sale directly to consumers as dietary supplements. We designed our study to determine the accuracy of supplement labels with regard to the presence and quantity of vinpocetine and picamilon. A validated ultra-high performance liquid chromatography-photodiode-array method was developed for the quantification of vinpocetine and picamilon. The separation was achieved using a reversed phase (C-18) column, photodiode array detection, and water/acetonitrile as the mobile phase. Vinpocetine and picamilon were detected at concentrations as low as 10 and 50 ng/mL, respectively. The presence of vinpocetine and picamilon was confirmed using reference standards. Twenty-three supplements labelled as containing vinpocetine were available for sale at two large supplement retail chains; 17 contained vinpocetine with quantities ranging from 0.3 to 32 mg per recommended daily serving. No vinpocetine was detected in six of the sampled supplements. The supplement label implied that vinpocetine was a constituent of lesser periwinkle in three of the supplements. Of the 31 picamilon supplements available for sale from a variety of retailers: 30 contained picamilon in quantities ranging from 2.7 to 721.5 mg per recommended daily serving. We found that consumers cannot obtain accurate information from supplement labels regarding the presence or quantity of vinpocetine and picamilon. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.
Rose, Jennifer S; Dierker, Lisa C; Hedeker, Donald; Mermelstein, Robin
2013-04-01
Research identifying nicotine dependence (ND) symptoms most appropriate for measurement of adolescent ND and invariant across the range of smoking exposure is hampered by limited sample size and variability of smoking behavior within independent studies. Integrative data analysis, the process of pooling and analyzing data from multiple studies, produces larger and more heterogeneous samples with which to evaluate measurement equivalence across the full continuum of smoking quantity and frequency. Data from two studies were pooled to obtain a large sample of adolescent and young adult smokers with considerable variability in smoking. We used moderated nonlinear factor analysis, which produces study equivalent ND scores, to simultaneously evaluate whether 14 DSM ND symptoms had equivalent psychometric properties (1) at different levels of smoking frequency and (2) across a continuous range of smoking quantity, after accounting for study differences. Nine of 14 symptoms were equivalent across levels of smoking frequency and quantity in probability of endorsement at different levels of ND and in ability to discriminate between levels of ND severity. A more precise ND factor score accounted for study and smoking related differences in symptom psychometric properties. DSM-IV symptoms may be used to reliably assess ND in young populations across a wide range of smoking quantity and frequency and within both nationally representative and geographically restricted samples with different study designs. Symptoms shared across studies produced an equivalently scaled ND factor score, demonstrating that integrating data for the purpose of studying ND in young smokers is viable. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
Venable, Rachel O; Stoker, Aaron M; Cook, Cristi R; Cockrell, Mary K; Cook, James L
2008-12-01
To determine the quantity (concentration) and quality (molecular weight) of synovial fluid hyaluronan with respect to presence and severity of osteoarthritis in stifle joints of dogs. 21 purpose-bred dogs and 6 clinically affected large-breed dogs (cranial cruciate ligament [CrCL] disease with secondary osteoarthritis). Research dogs underwent arthroscopic surgery in 1 stifle joint to induce osteoarthritis via CrCL transection (CrCLt; n=5 stifle joints), femoral condylar articular cartilage groove creation (GR; 6), or meniscal release (MR; 5); 5 had sham surgery (SH) performed. Contralateral stifle joints (n=21) were used as unoperated control joints. Synovial fluid was obtained from research dogs at time 0 and 12 weeks after surgery and from clinically affected dogs prior to surgery. All dogs were assessed for lameness, radiographic signs of osteoarthritis, and pathologic findings on arthroscopy as well as for quantity and quality of hyaluronan. Clinically affected dogs had significantly greater degrees of pathologic findings, compared with dogs with surgically induced osteoarthritis (ie, those with CrCLt, GR, and MR stifle joints), and with respect to lameness scores, radiographic signs of osteoarthritis, pathologic findings on arthroscopy, and synovial fluid hyaluronan concentration. Synovial fluid from stifle joints of dogs with surgically induced osteoarthritis had hyaluronan bands at 35 kd on western blots that synovial fluid from SH and clinically affected stifle joints did not. Synovial fluid hyaluronan quantity and quality were altered in stifle joints of dogs with osteoarthritis, compared with control stifle joints. A specific hyaluronan protein fragment may be associated with early pathologic changes in affected joints.
Unleashing Empirical Equations with "Nonlinear Fitting" and "GUM Tree Calculator"
NASA Astrophysics Data System (ADS)
Lovell-Smith, J. W.; Saunders, P.; Feistel, R.
2017-10-01
Empirical equations having large numbers of fitted parameters, such as the international standard reference equations published by the International Association for the Properties of Water and Steam (IAPWS), which form the basis of the "Thermodynamic Equation of Seawater—2010" (TEOS-10), provide the means to calculate many quantities very accurately. The parameters of these equations are found by least-squares fitting to large bodies of measurement data. However, the usefulness of these equations is limited since uncertainties are not readily available for most of the quantities able to be calculated, the covariance of the measurement data is not considered, and further propagation of the uncertainty in the calculated result is restricted since the covariance of calculated quantities is unknown. In this paper, we present two tools developed at MSL that are particularly useful in unleashing the full power of such empirical equations. "Nonlinear Fitting" enables propagation of the covariance of the measurement data into the parameters using generalized least-squares methods. The parameter covariance then may be published along with the equations. Then, when using these large, complex equations, "GUM Tree Calculator" enables the simultaneous calculation of any derived quantity and its uncertainty, by automatic propagation of the parameter covariance into the calculated quantity. We demonstrate these tools in exploratory work to determine and propagate uncertainties associated with the IAPWS-95 parameters.
LES tests on airfoil trailing edge serration
NASA Astrophysics Data System (ADS)
Zhu, Wei Jun; Shen, Wen Zhong
2016-09-01
In the present study, a large number of acoustic simulations are carried out for a low noise airfoil with different Trailing Edge Serrations (TES). The Ffowcs Williams-Hawkings (FWH) acoustic analogy is used for noise prediction at trailing edge. The acoustic solver is running on the platform of our in-house incompressible flow solver EllipSys3D. The flow solution is first obtained from the Large Eddy Simulation (LES), the acoustic part is then carried out based on the instantaneous hydrodynamic pressure and velocity field. To obtain the time history data of sound pressure, the flow quantities are integrated around the airfoil surface through the FWH approach. For all the simulations, the chord based Reynolds number is around 1.5x106. In the test matrix, the effects from angle of attack, the TE flap angle, the length/width of the TES are investigated. Even though the airfoil under investigation is already optimized for low noise emission, most numerical simulations and wind tunnel experiments show that the noise level is further decreased by adding the TES device.
NASA Astrophysics Data System (ADS)
Honda, Z.; Sato, S.; Hagiwara, M.; Kida, T.; Sakai, M.; Fukuda, T.; Kamata, N.
2016-07-01
A simple method for the preparation of bulk quantities of magnetic carbon materials, which contain uniformly dispersed transition metals (M = Fe, Co, Ni, and Cu) as the magnetic components, is presented. By using highly chlorinated metal phthalocyanine as the building block and potassium as the coupling reagent, phthalocyanine-based carbon materials (PBCMs) containing transition metals were obtained. Our experiments demonstrate the structure of these PBCMs consists of transition metals embedded in graphitic carbon that includes a square planar MN4 magnetic core and the Fe and Co-PBCM possess spontaneous magnetization at room temperature. In addition, carbon-coated transition metal particles were obtained by the Wurtz-type reaction with excess amount of potassium coupling agent. The large transition metal surface area and magnetization of these M-PBCMs are useful for spintronic and catalytic applications.
NASA Astrophysics Data System (ADS)
Guo, Yu-Feng; Fang, Wei-Jun; Fu, Jie-Ru; Wu, Yun; Zheng, Jun; Gao, Gui-Qi; Chen, Cheng; Yan, Rui-Wen; Huang, Shou-Guo; Wang, Chun-Chang
2018-03-01
Compared with pure MOFs, core-shell heterostructures of noble-metal@MOFs have attracted tremendous interest due to their unique structure and extensive applications. In the present study, we have successfully synthesized well-defined core-shell Ag@ZIF-8 nanowires. The products growth process has been investigated by examining the products obtained at different intervals and the thickness of ZIF-8 shell ranging from 30 to 100 nm can be technically obtained by tuning the quantity of Ag nanowires. Ag@ZIF-8 has been proven to possess large specific surfaces and high thermal stability. Additionally, the antibacterial activity of Ag@ZIF-8 is further tested against Bacillus subtilis and Escherichia coli BL21. The results reveal that Ag@ZIF-8 core-shell heterostructure nanowires have effective activities against the two types of bacterial strains.
Zero-gravity quantity gaging system
NASA Technical Reports Server (NTRS)
1989-01-01
The Zero-Gravity Quantity Gaging System program is a technology development effort funded by NASA-LeRC and contracted by NASA-JSC to develop and evaluate zero-gravity quantity gaging system concepts suitable for application to large, on-orbit cryogenic oxygen and hydrogen tankage. The contract effective date was 28 May 1985. During performance of the program, 18 potential quantity gaging approaches were investigated for their merit and suitability for gaging two-phase cryogenic oxygen and hydrogen in zero-gravity conditions. These approaches were subjected to a comprehensive trade study and selection process, which found that the RF modal quantity gaging approach was the most suitable for both liquid oxygen and liquid hydrogen applications. This selection was made with NASA-JSC concurrence.
NASA Technical Reports Server (NTRS)
Kriegler, F. J.
1974-01-01
The MIDAS System is described as a third-generation fast multispectral recognition system able to keep pace with the large quantity and high rates of data acquisition from present and projected sensors. A principal objective of the MIDAS program is to provide a system well interfaced with the human operator and thus to obtain large overall reductions in turnaround time and significant gains in throughput. The hardware and software are described. The system contains a mini-computer to control the various high-speed processing elements in the data path, and a classifier which implements an all-digital prototype multivariate-Gaussian maximum likelihood decision algorithm operating at 200,000 pixels/sec. Sufficient hardware was developed to perform signature extraction from computer-compatible tapes, compute classifier coefficients, control the classifier operation, and diagnose operation.
An ab initio electronic transport database for inorganic materials.
Ricci, Francesco; Chen, Wei; Aydemir, Umut; Snyder, G Jeffrey; Rignanese, Gian-Marco; Jain, Anubhav; Hautier, Geoffroy
2017-07-04
Electronic transport in materials is governed by a series of tensorial properties such as conductivity, Seebeck coefficient, and effective mass. These quantities are paramount to the understanding of materials in many fields from thermoelectrics to electronics and photovoltaics. Transport properties can be calculated from a material's band structure using the Boltzmann transport theory framework. We present here the largest computational database of electronic transport properties based on a large set of 48,000 materials originating from the Materials Project database. Our results were obtained through the interpolation approach developed in the BoltzTraP software, assuming a constant relaxation time. We present the workflow to generate the data, the data validation procedure, and the database structure. Our aim is to target the large community of scientists developing materials selection strategies and performing studies involving transport properties.
NASA Technical Reports Server (NTRS)
Spradley, L. W.; Dean, W. G.; Karu, Z. S.
1976-01-01
The thermal acoustic oscillations (TAO) data base was expanded by running a large number of tubes over a wide range of parameters known to affect the TAO phenomenon. These parameters include tube length, wall thickness, diameter, material, insertion length and length-to-diameter ratio. Emphasis was placed on getting good boiloff data. A large quantity of data was obtained, reduced, correlated and analyzed and is presented. Also presented are comparisons with previous types of correlations. These comparisons show that the boiloff data did not correlate with intensity. The data did correlate in the form used by Rott, that is boiloff versus TAO pressure squared times frequency to the one-half power. However, this latter correlation required a different set of correlation constants, slope and intercept, for each tube tested.
Study of Polyolefines Waste Thermo-Destruction in Large Laboratory and in Industrial Installations
2014-12-15
coke ”–waste after thermo-destruction carried out on the module No 2 showed an content to 46.1% of ash [20]. This ash content indicates a very large... coke (post-production waste) from the wastes thermo-destruction on 2 modules of vertical modular installation for thermo-destruction of used polymer...of receivedwaste water, the quantity of received coke , the quantity of gaseous product in periods of carrying out installation work before (first
Applied research of shaking table for scandium concentration from a silicate ore
NASA Astrophysics Data System (ADS)
Yan, P.; Zhang, G. F.; Gao, L.; Shi, B. H.; Shi, Z.; Yang, Y. D.
2018-03-01
A poor magnetite iron ore is a super large independent scandium deposit with over the multi-billion potential utilizable value. Shaking table separation is very useful for impurities removing and scandium content increasing as a follow-up step of high-intensity magnetic separation. In the present study, a satisfactory index, namely scandium content of 83.10 g/t and recovery rate of 79.45 wt%, was obtained by shaking table separation. The good result was achieved under the conditions which the parameters were feed concentrate of 18 wt%, feeding quantity of 11 L/min, stroke frequency of 275 times/min and stroke of 17mm.
Sum and mean. Standard programs for activation analysis.
Lindstrom, R M
1994-01-01
Two computer programs in use for over a decade in the Nuclear Methods Group at NIST illustrate the utility of standard software: programs widely available and widely used, in which (ideally) well-tested public algorithms produce results that are well understood, and thereby capable of comparison, within the community of users. Sum interactively computes the position, net area, and uncertainty of the area of spectral peaks, and can give better results than automatic peak search programs when peaks are very small, very large, or unusually shaped. Mean combines unequal measurements of a single quantity, tests for consistency, and obtains the weighted mean and six measures of its uncertainty.
SALT EFFECTS ON EGGS AND NAUPLII OF ARTEMIA SALINA L
Boone, Eleanor; Baas-Becking, L. G. M.
1931-01-01
Eggs of Artemia salina L., the brine shrimp, are easily obtainable in large quantities. Ecdysis takes place in two stages: (a) extrusion of the inner membrane, and (b) ecdysis of the nauplius from that membrane. The conditions which allow for the former are much more varied than those for the latter. Nauplii form in only solutions of a few sodium salts; and, in Mg, Ca, and Sr salts, potassium is very toxic. The possible environment for the nauplii (1 M total molarity) has been ascertained for chlorides of Na, K, Mg, and Ca. The facts observed account for the peculiar distribution of the organism. PMID:19872620
UNIX-based data management system for the Mobile Satellite Propagation Experiment (PiFEx)
NASA Technical Reports Server (NTRS)
Kantak, Anil V.
1987-01-01
A new method is presented for handling data resulting from Mobile Satellite propagation experiments such as the Pilot Field Experiment (PiFEx) conducted by JPL. This method uses the UNIX operating system and C programming language. The data management system is implemented on a VAX minicomputer. The system automatically divides the large data file housing data from various experiments under a predetermined format into various individual files containing data from each experiment. The system also has a number of programs written in C and FORTRAN languages to allow the researcher to obtain meaningful quantities from the data at hand.
Simplified formula for mean cycle-slip time of phase-locked loops with steady-state phase error.
NASA Technical Reports Server (NTRS)
Tausworthe, R. C.
1972-01-01
Previous work shows that the mean time from lock to a slipped cycle of a phase-locked loop is given by a certain double integral. Accurate numerical evaluation of this formula for the second-order loop is extremely vexing because the difference between exponentially large quantities is involved. The presented article demonstrates a method in which a much-reduced precision program can be used to obtain the mean first-cycle slip time for a loop of arbitrary degree tracking at a specified SNR and steady-state phase error. It also presents a simple approximate formula that is asymptotically tight at higher loop SNR.
2011-03-04
direct relationships between calculated quantities obtained by DFT and the “conveniently measurable” quantities α and rn...VCH Verlag, Weinheim, 2004). [11] A. D. Becke, “Density- funtional Thermochemistry. III. The Role of Exact Exchange”, J. Chem. Phys. 98, 5648-5652
Atomic Layer Deposition on Gram Quantities of Multi-Walled Carbon Nanotubes
2009-06-03
the amount of reactant that is lost to the vacuum pump . Recent work has demonstrated the feasibility of ALD on gram quantities of nanopowders in a...and left to outgas under vacuum for 24 h. Vacuum was obtained using a dual-stage rotary vane pump . Pressure was monitored with a Baratron capacitance...Atomic layer deposition on gram quantities of multi-walled carbon nanotubes This article has been downloaded from IOPscience. Please scroll down to
Detector Dewar cooler assemblies trade-off with equipment needs: a key issue for cost reduction
NASA Astrophysics Data System (ADS)
Chatard, Jean-Pierre
1996-06-01
Low cost equipment is the universal motto with the decrease in military budgets. A large panoply exists to solve partially this problem, such as simplification of the process, industrialization and the use of a collective manufacturing concept; but this is not enough. In the field of IRFPA using Mercury Cadmium Telluride (MCT), Sofradir has spent a lot of time in order to develop a very simple process to ensure producibility which has been totally demonstrated today. The production of more than 25 complex IRFPA per month has also allowed us to industrialize the process. A key factor is quantities. Today the only solution to increase quantities is to standardize detectors but in the field of IRFPA it is not so easy because each imaging system is specific. One solution to decrease the cost is to obtain the best trade-off between the application and the technology. As an example, people focus on indium antimonide staring array detectors today as they consider them as less expensive than other cooled infrared detector technologies. This is just because people focus on the FPA only, not on the global cost of the equipment. It will be demonstrated in this paper that MCT is a material so flexible that it is possible to obtain InSb detector performance at a higher temperature which allows decreased cost, volume and weight of the infrared equipment.
Cell Expansion During Directed Differentiation of Stem Cells Toward the Hepatic Lineage
Raju, Ravali; Chau, David; Cho, Dong Seong; Park, Yonsil; Verfaillie, Catherine M.
2017-01-01
The differentiation of human pluripotent stem cells toward the hepatocyte lineage can potentially provide an unlimited source of functional hepatocytes for transplantation and extracorporeal bioartificial liver applications. It is anticipated that the quantities of cells needed for these applications will be in the order of 109–1010 cells, because of the size of the liver. An ideal differentiation protocol would be to enable directed differentiation to the hepatocyte lineage with simultaneous cell expansion. We introduced a cell expansion stage after the commitment of human embryonic stem cells to the endodermal lineage, to allow for at least an eightfold increase in cell number, with continuation of cell maturation toward the hepatocyte lineage. The progressive changes in the transcriptome were measured by expression array, and the expression dynamics of certain lineage markers was measured by mass cytometry during the differentiation and expansion process. The findings revealed that while cells were expanding they were also capable of progressing in their differentiation toward the hepatocyte lineage. In addition, our transcriptome, protein and functional studies, including albumin secretion, drug-induced CYP450 expression and urea production, all indicated that the hepatocyte-like cells obtained with or without cell expansion are very similar. This method of simultaneous cell expansion and hepatocyte differentiation should facilitate obtaining large quantities of cells for liver cell applications. PMID:27806669
Bayesian Analysis of a Simple Measurement Model Distinguishing between Types of Information
NASA Astrophysics Data System (ADS)
Lira, Ignacio; Grientschnig, Dieter
2015-12-01
Let a quantity of interest, Y, be modeled in terms of a quantity X and a set of other quantities Z. Suppose that for Z there is type B information, by which we mean that it leads directly to a joint state-of-knowledge probability density function (PDF) for that set, without reference to likelihoods. Suppose also that for X there is type A information, which signifies that a likelihood is available. The posterior for X is then obtained by updating its prior with said likelihood by means of Bayes' rule, where the prior encodes whatever type B information there may be available for X. If there is no such information, an appropriate non-informative prior should be used. Once the PDFs for X and Z have been constructed, they can be propagated through the measurement model to obtain the PDF for Y, either analytically or numerically. But suppose that, at the same time, there is also information of type A, type B or both types together for the quantity Y. By processing such information in the manner described above we obtain another PDF for Y. Which one is right? Should both PDFs be merged somehow? Is there another way of applying Bayes' rule such that a single PDF for Y is obtained that encodes all existing information? In this paper we examine what we believe should be the proper ways of dealing with such a (not uncommon) situation.
Konował, Emilia; Sybis, Marta; Modrzejewska-Sikorska, Anna; Milczarek, Grzegorz
2017-11-01
Various commercial dextrins were used as reducing and stabilizing agents for a novel one-step synthesis of silver nanoparticles from ammonia complexes of silver ions. As a result, stable colloids of silver were formed during the reaction with the particle size being the function of the dextrin type. The obtained colloids were characterized by UV-vis spectrophotometry, size distribution (using Non-Invasive Backscatter optics) and transmission electron microscopy (TEM). The achieved results clearly indicate the possibility of low-cost production of large quantities of colloidal silver nanoparticles using materials derived from renewable sources. The resulting silver colloids can be used for different purposes, e.g. as bactericidal agents. Combination of the aforementioned properties of nanosilver particles with plasticizing properties of dextrin enables to obtain cement mortars with increased workability and enhanced compressive strength. Moreover, the obtained material is also characterized by increased immunity to adverse impact of microorganisms. Copyright © 2017 Elsevier B.V. All rights reserved.
Drilling to Extract Liquid Water on Mars: Feasible and Worth the Investment
NASA Technical Reports Server (NTRS)
Stoker, C.
2004-01-01
A critical application for the success of the Exploration Mission is developing cost effective means to extract resources from the Moon and Mars needed to support human exploration. Water is the most important resource in this regard, providing a critical life support consumable, the starting product of energy rich propellants, energy storage media (e.g. fuel cells), and a reagent used in virtually all manufacturing processes. Water is adsorbed and chemically bound in Mars soils, ice is present near the Martian surface at high latitudes, and water vapor is a minor atmospheric constituent, but extracting meaningful quantities requires large complex mechanical systems, massive feedstock handling, and large energy inputs. Liquid water aquifers are almost certain to be found at a depth of several kilometers on Mars based on our understanding of the average subsurface thermal gradient, and geological evidence from recent Mars missions suggests liquid water may be present much closer to the surface at some locations. The discovery of hundreds of recent water-carved gullies on Mars indicates liquid water can be found at depths of 200-500 meters in many locations. Drilling to obtain liquid water via pumping is therefore feasible and could lower the cost and improve the return of Mars exploration more than any other ISRU technology on the horizon. On the Moon, water ice may be found in quantity in permanently shadowed regions near the poles.
Nava-Valente, Noemí; Alvarado-Lassman, Alejandro; Nativitas-Sandoval, Liliana S; Mendez-Contreras, Juan M
2016-01-01
Thermal pretreatment effect of a mixture of organic wastes (physicochemical sludge, excreta of broiler chickens and sugarcane wastes (SCW)) in the solubilization and biodegradability organic matter as well as bioenergy production by anaerobic digestion was evaluated. Two different mixtures of physicochemical sludge, excreta of broiler chickens and SCW (70%, 15%, 15% and 60%, 20%, 20% of VS, respectively) were treated at different temperatures (80 °C, 85 °C and 90 °C) and contact time (30, 60 and 90 min). Results indicate that, organic matter solubilization degree increased from 1.14 to 6.56%; subsequently, in the anaerobic digestion process, an increase of 50% in the volatile solids removal and 10% in biogas production was observed, while, retention time decreased from 23 up to 9 days. The results obtained were similar to pilot-scale. In both experimental scales it showed that the synergy produced by the simultaneous anaerobic digestion of different substrates could increase bioenergy production up to 1.3 L bio g(-1) VS removed and 0.82 L CH4 g(-1) VS removed. The treatment conditions presented in this study allow for large residue quantities to be treated and large bioenergy quantities to be produced (10% higher than during conventional treatment) without increasing the anaerobic digester volume.
Conservation laws and conserved quantities for (1+1)D linearized Boussinesq equations
NASA Astrophysics Data System (ADS)
Carvalho, Cindy; Harley, Charis
2017-05-01
Conservation laws and physical conserved quantities for the (1+1)D linearized Boussinesq equations at a constant water depth are presented. These equations describe incompressible, inviscid, irrotational fluid flow in the form of a non steady solitary wave. A systematic multiplier approach is used to obtain the conservation laws of the system of third order partial differential equations (PDEs) in dimensional form. Physical conserved quantities are derived by integrating the conservation laws in the direction of wave propagation and imposing decaying boundary conditions in the horizontal direction. One of these is a newly discovered conserved quantity which relates to an energy flux density.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Medeiros, L.C.; Belden, R.P.
Selenium (Se) content of elk, deer, bison and beef were measured and compared. Samples were obtained from animals grazed on soil known to contain high, but variable amounts of Se. Beef were feedlot grazed and elk, deer, and bison were from captive or semi-captive herds. Selenium content was determined by graphite furnace after high pressure wet microwave digestion of samples. Deer and bison contained more Se than elk or beef. On a dry weight basis, deer contained more Se than bison. Game species contained more Se than beef. Within samples from male elk and deer and elk and bison ofmore » both genders, there were interactions between specie and muscle effects. Muscle and gender did not significantly influence Se content. The animals from which these samples were taken were supplemented with feeds grown on high Se containing soils, which was reflected in all values. Se values were twofold higher than those previously reported for meat. Those consuming large quantities of game from areas with high Se soil may need to monitor Se intake to avoid consuming excessive quantities.« less
Review of probabilistic analysis of dynamic response of systems with random parameters
NASA Technical Reports Server (NTRS)
Kozin, F.; Klosner, J. M.
1989-01-01
The various methods that have been studied in the past to allow probabilistic analysis of dynamic response for systems with random parameters are reviewed. Dynamic response may have been obtained deterministically if the variations about the nominal values were small; however, for space structures which require precise pointing, the variations about the nominal values of the structural details and of the environmental conditions are too large to be considered as negligible. These uncertainties are accounted for in terms of probability distributions about their nominal values. The quantities of concern for describing the response of the structure includes displacements, velocities, and the distributions of natural frequencies. The exact statistical characterization of the response would yield joint probability distributions for the response variables. Since the random quantities will appear as coefficients, determining the exact distributions will be difficult at best. Thus, certain approximations will have to be made. A number of techniques that are available are discussed, even in the nonlinear case. The methods that are described were: (1) Liouville's equation; (2) perturbation methods; (3) mean square approximate systems; and (4) nonlinear systems with approximation by linear systems.
NASA Technical Reports Server (NTRS)
Van Volkenburgh, E.; Cleland, R. E.; Watanabe, M.
1990-01-01
The quantity and quality of light required for light-stimulated cell expansion in leaves of Phaseolus vulgaris L. have been determined. Seedlings were grown in dim red light (RL; 4 micromoles photons m-2 s-1) until cell division in the primary leaves was completed, then excised discs were incubated in 10 mM sucrose plus 10 mM KCl in a variety of light treatments. The growth response of discs exposed to continuous white light (WL) for 16 h was saturated at 100 micromoles m-2 s-1, and did not show reciprocity. Extensive, but not continuous, illumination was needed for maximal growth. The wavelength dependence of disc expansion was determined from fluence-response curves obtained from 380 to 730 nm provided by the Okazaki Large Spectrograph. Blue (BL; 460 nm) and red light (RL; 660 nm) were most effective in promoting leaf cell growth, both in photosynthetically active and inhibited leaf discs. Far-red light (FR; 730 nm) reduced the effectiveness of RL, but not BL, indicating that phytochrome and a separate blue-light receptor mediate expansion of leaf cells.
Improved artificial saliva for studying the cariogenic effect of carbohydrates.
Björklund, Marika; Ouwehand, Arthur C; Forssten, Sofia D
2011-07-01
Saliva is a complex fluid that possesses many important functions regarding oral health. Many in vitro studies require relatively large quantities of saliva. While natural saliva would be the material of choice, it is difficult to obtain in sufficient quantities and varies in composition. Substitutes mimicking the physicochemical properties of saliva have been developed, but these are not appropriate to study the growth of mutans streptococci. Brain Heart Infusion (BHI) has been commonly used for this, but this medium is richer in nutrients than saliva. We therefore developed artificial saliva (AS) with nutrient levels resembling those in natural saliva as a substitute for natural human saliva (HS) to study the influence of different carbon sources on mutans streptococci growth. Growth of a wild-type Streptococcus mutans strain and S. mutans ATCC 15175 in BHI, HS, and AS was monitored anaerobically. Growth of S. mutans in the modified AS was very similar to the growth in HS, both in the absence and presence of different carbon sources. We therefore conclude that the developed AS is suitable for in vitro tests on S. mutans growth.
A nonlinear model for ionic polymer metal composites as actuators
NASA Astrophysics Data System (ADS)
Bonomo, C.; Fortuna, L.; Giannone, P.; Graziani, S.; Strazzeri, S.
2007-02-01
This paper introduces a comprehensive nonlinear dynamic model of motion actuators based on ionic polymer metal composites (IPMCs) working in air. Significant quantities ruling the acting properties of IPMC-based actuators are taken into account. The model is organized as follows. As a first step, the dependence of the IPMC absorbed current on the voltage applied across its thickness is taken into account; a nonlinear circuit model is proposed to describe this relationship. In a second step the transduction of the absorbed current into the IPMC mechanical reaction is modelled. The model resulting from the cascade of both the electrical and the electromechanical stages represents a novel contribution in the field of IPMCs, capable of describing the electromechanical behaviour of these materials and predicting relevant quantities in a large range of applied signals. The effect of actuator scaling is also investigated, giving interesting support to the activities involved in the design of actuating devices based on these novel materials. Evidence of the excellent agreement between the estimations obtained by using the proposed model and experimental signals is given.
Preparation, purification and analyses of thirteen alkali-stable dinucleotides from ribonucleic acid
Trim, A. R.; Parker, Janet E.
1970-01-01
Of the 16 alkali-stable dinucleotides known to be obtained by hydrolysis of commercial yeast RNA with alkali, 13 were prepared in quantities of the order of 10mg or more. The samples, with only one exception, contain at least 90% of dinucleotide, and spectroscopic constants and nucleotide-sequence determinations, although not conclusive, indicate a high degree of purity of these products. The small dinucleotide fraction in 150g of RNA hydrolysed with alkali (1–2% of the total nucleotides) was separated from the mononucleotides by stepwise ion-exchange chromatography on DEAE-cellulose columns and resolved into seven fractions containing from one to four different dinucleotides by electrophoresis on paper at pH3.0. These fractions were resolved into their constituent dinucleotides by chromatography in ammonium sulphate. Contamination of the products by impurities from the paper was minimized by washing it before using it for chromatography or electrophoresis and, by using a thick grade of paper (Whatman no. 17), it was possible to handle and purify relatively large quantities of nucleotides. PMID:5435489
Multivessel supercritical fluid extraction of food items in Total Diet Study.
Hopper, M L; King, J W; Johnson, J H; Serino, A A; Butler, R J
1995-01-01
An off-line, large capacity, multivessel supercritical fluid extractor (SFE) was designed and constructed for extraction of large samples. The extractor can simultaneously process 1-6 samples (15-25 g) by using supercritical carbon dioxide (SC-CO2), which is relatively nontoxic and nonflammable, as the solvent extraction medium. Lipid recoveries for the SFE system were comparable to those obtained by blending or Soxhlet extraction procedures. Extractions at 10,000 psi, 80 degrees C, expanded gaseous CO2 flow rates of 4-5 L/min (35 degrees C), and 1-3 h extraction times gave reproducible lipid recoveries for pork sausage (relative standard deviation [RSD], 1.32%), corn chips (RSD, 0.46%), cheddar cheese (RSD, 1.14%), and peanut butter (RSD, 0.44%). In addition, this SFE system gave reproducible recoveries (> 93%) for butter fortified with cis-chlordane and malathion at the 100 ppm and 0.1 ppm levels. Six portions each of cheddar cheese, saltine crackers, sandwich cookies, and ground hamburger also were simultaneously extracted with SC-CO2 and analyzed for incurred pesticide residues. Results obtained with this SFE system were reproducible and comparable with results from organic-solvent extraction procedures currently used in the Total Diet Study; therefore, use and disposal of large quantities of organic solvents can be eliminated.
An Equation-Free Reduced-Order Modeling Approach to Tropical Pacific Simulation
NASA Astrophysics Data System (ADS)
Wang, Ruiwen; Zhu, Jiang; Luo, Zhendong; Navon, I. M.
2009-03-01
The “equation-free” (EF) method is often used in complex, multi-scale problems. In such cases it is necessary to know the closed form of the required evolution equations about oscopic variables within some applied fields. Conceptually such equations exist, however, they are not available in closed form. The EF method can bypass this difficulty. This method can obtain oscopic information by implementing models at a microscopic level. Given an initial oscopic variable, through lifting we can obtain the associated microscopic variable, which may be evolved using Direct Numerical Simulations (DNS) and by restriction, we can obtain the necessary oscopic information and the projective integration to obtain the desired quantities. In this paper we apply the EF POD-assisted method to the reduced modeling of a large-scale upper ocean circulation in the tropical Pacific domain. The computation cost is reduced dramatically. Compared with the POD method, the method provided more accurate results and it did not require the availability of any explicit equations or the right-hand side (RHS) of the evolution equation.
Measuring the degradation level of polymer films subjected to partial discharges
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bozzo, R.; Gemme, C.; Guastavino, F.
1996-12-31
Polymer films have been subjected to partial discharge (PD) aging. It is shown that statistical quantities derived from partial discharges patterns can be related to test conditions, film characteristics and degradation level. PDs have been measured by means of a digital system. Several resulting PD patterns have been elaborated and about 50 derived and statistical quantities have been obtained for each pattern. The effects of the test conditions on the derived quantities has been studied with relevance to the following items: To recognize the kind of film under test; to correlate the value of quantities with the degradation level ofmore » the film (i.e., to focus at the quantities which change with time); to find a link between the quantities values and the test ambient conditions (i.e., relative humidity); to determine the influence of the film thickness; and to evidence the effect of the voltage level.« less
Deterministic photon bias in speckle imaging
NASA Technical Reports Server (NTRS)
Beletic, James W.
1989-01-01
A method for determining photo bias terms in speckle imaging is presented, and photon bias is shown to be a deterministic quantity that can be calculated without the use of the expectation operator. The quantities obtained are found to be identical to previous results. The present results have extended photon bias calculations to the important case of the bispectrum where photon events are assigned different weights, in which regime the bias is a frequency dependent complex quantity that must be calculated for each frame.
Increased urbanization results in a larger percentage of connected impervious areas and can contribute large quantities of stormwater runoff and significant quantities of debris and pollutants (e.g., litter, oils, microorganisms, sediments, nutrients, organic matter, and heavy me...
The plasma separation process as a pre-cursor for large scale radioisotope production
NASA Astrophysics Data System (ADS)
Stevenson, Nigel R.
2001-07-01
Radioisotope production generally employs either accelerators or reactors to convert stable (usually enriched) isotopes into the desired product species. Radioisotopes have applications in industry, environmental sciences, and most significantly in medicine. The production of many potentially useful radioisotopes is significantly hindered by the lack of availability or by the high cost of key enriched stable isotopes. To try and meet this demand, certain niche enrichment processes have been developed and commercialized. Calutrons, centrifuges, and laser separation processes are some of the devices and techniques being employed to produce large quantities of selective enriched stable isotopes. Nevertheless, the list of enriched stable isotopes in sufficient quantities remains rather limited and this continues to restrict the availability of many radioisotopes that otherwise could have a significant impact on society. The Plasma Separation Process is a newly available commercial technique for producing large quantities of a wide range of enriched isotopes and thereby holds promise of being able to open the door to producing new and exciting applications of radioisotopes in the future.
NASA Technical Reports Server (NTRS)
Christenson, D.; Gordon, M.; Kistler, R.; Kriegler, F.; Lampert, S.; Marshall, R.; Mclaughlin, R.
1977-01-01
A third-generation, fast, low cost, multispectral recognition system (MIDAS) able to keep pace with the large quantity and high rates of data acquisition from large regions with present and projected sensots is described. The program can process a complete ERTS frame in forty seconds and provide a color map of sixteen constituent categories in a few minutes. A principle objective of the MIDAS program is to provide a system well interfaced with the human operator and thus to obtain large overall reductions in turn-around time and significant gains in throughput. The hardware and software generated in the overall program is described. The system contains a midi-computer to control the various high speed processing elements in the data path, a preprocessor to condition data, and a classifier which implements an all digital prototype multivariate Gaussian maximum likelihood or a Bayesian decision algorithm. Sufficient software was developed to perform signature extraction, control the preprocessor, compute classifier coefficients, control the classifier operation, operate the color display and printer, and diagnose operation.
Comparison of results obtained with various sensors used to measure fluctuating quantities in jets.
NASA Technical Reports Server (NTRS)
Parthasarathy, S. P.; Massier, P. F.; Cuffel, R. F.
1973-01-01
An experimental investigation has been conducted to compare the results obtained with six different instruments that sense fluctuating quantities in free jets. These sensors are typical of those that have recently been used by various investigators who are engaged in experimental studies of jet noise. Intensity distributions and two-point correlations with space separation and time delay were obtained. The static pressure, density, and velocity fluctuations are well correlated over the entire cross section of the jet and the cross-correlations persist for several jet diameters along the flow direction. The eddies appear to be flattened in the flow direction by a ratio of 0.4.
NASA Astrophysics Data System (ADS)
Siregar, A. P.; Juniati, D.; Sulaiman, R.
2018-01-01
This study involving 2 grade VIII students was taken place in SMPK Anak Bangsa Surabaya. Subjects were selected using equal mathematics ability criteria. Data was collected using provision of problem-solving tasks and followed by a task-based interview. Obtained data was analysed through the following steps, which are data reduction, data presentation, and conclusions. Meanwhile, to obtain a valid data, in this study, researchers used data triangulation. The results indicated that in the problem number 1 about identifying patterns, the subjects of male and female show a tendency of similarities in stating what is known and asked the question. However, the male students provided a more specific answer in explaining the magnitude of the difference between the first quantity and the increased differences in the other quantities. Related the activities in determining the relationship between two quantities, male subjects and women subject tended to have similarities in the sense of using trial and error on existing mathematical operations. It can be concluded that the functional way of thinking both subjects is relatively identic. Nevertheless, the male subject showed the more specific answer in finding the difference between the two quantities and finding the correspondence relationship between the quantities.
Quantity, Revisited: An Object-Oriented Reusable Class
NASA Technical Reports Server (NTRS)
Funston, Monica Gayle; Gerstle, Walter; Panthaki, Malcolm
1998-01-01
"Quantity", a prototype implementation of an object-oriented class, was developed for two reasons: to help engineers and scientists manipulate the many types of quantities encountered during routine analysis, and to create a reusable software component to for large domain-specific applications. From being used as a stand-alone application to being incorporated into an existing computational mechanics toolkit, "Quantity" appears to be a useful and powerful object. "Quantity" has been designed to maintain the full engineering meaning of values with respect to units and coordinate systems. A value is a scalar, vector, tensor, or matrix, each of which is composed of Value Components, each of which may be an integer, floating point number, fuzzy number, etc., and its associated physical unit. Operations such as coordinate transformation and arithmetic operations are handled by member functions of "Quantity". The prototype has successfully tested such characteristics as maintaining a numeric value, an associated unit, and an annotation. In this paper we further explore the design of "Quantity", with particular attention to coordinate systems.
Variability and Maintenance of Turbulence in the Very Stable Boundary Layer
NASA Astrophysics Data System (ADS)
Mahrt, Larry
2010-04-01
The relationship of turbulence quantities to mean flow quantities, such as the Richardson number, degenerates substantially for strong stability, at least in those studies that do not place restrictions on minimum turbulence or non-stationarity. This study examines the large variability of the turbulence for very stable conditions by analyzing four months of turbulence data from a site with short grass. Brief comparisons are made with three additional sites, one over short grass on flat terrain and two with tall vegetation in complex terrain. For very stable conditions, any dependence of the turbulence quantities on the mean wind speed or bulk Richardson number becomes masked by large scatter, as found in some previous studies. The large variability of the turbulence quantities is due to random variations and other physical influences not represented by the bulk Richardson number. There is no critical Richardson number above which the turbulence vanishes. For very stable conditions, the record-averaged vertical velocity variance and the drag coefficient increase with the strength of the submeso motions (wave motions, solitary waves, horizontal modes and numerous more complex signatures). The submeso motions are on time scales of minutes and not normally considered part of the mean flow. The generation of turbulence by such unpredictable motions appears to preclude universal similarity theory for predicting the surface stress for very stable conditions. Large variation of the stress direction with respect to the wind direction for the very stable regime is also examined. Needed additional work is noted.
Method for obtaining structure and interactions from oriented lipid bilayers
Lyatskaya, Yulia; Liu, Yufeng; Tristram-Nagle, Stephanie; Katsaras, John; Nagle, John F.
2009-01-01
Precise calculations are made of the scattering intensity I(q) from an oriented stack of lipid bilayers using a realistic model of fluctuations. The quantities of interest include the bilayer bending modulus Kc , the interbilayer interaction modulus B, and bilayer structure through the form factor F(qz). It is shown how Kc and B may be obtained from data at large qz where fluctuations dominate. Good estimates of F(qz) can be made over wide ranges of qz by using I(q) in q regions away from the peaks and for qr≠0 where details of the scattering domains play little role. Rough estimates of domain sizes can also be made from smaller qz data. Results are presented for data taken on fully hydrated, oriented DOPC bilayers in the Lα phase. These results illustrate the advantages of oriented samples compared to powder samples. PMID:11304287
NASA Technical Reports Server (NTRS)
Ahmadi, A. R.
1981-01-01
A low frequency unsteady lifting-line theory is developed for a harmonically oscillating wing of large aspect ratio. The wing is assumed to be chordwise rigid but completely flexible in the span direction. The theory is developed by use of the method of matched asymptotic expansions which reduces the problem from a singular integral equation to quadrature. The wing displacements are prescribed and the pressure field, airloads, and unsteady induced downwash are obtained in closed form. The influence of reduced frequency, aspect ratio, planform shape, and mode of oscillation on wing aerodynamics is demonstrated through numerical examples. Compared with lifting-surface theory, computation time is reduced significantly. Using the present theory, the energetic quantities associated with the propulsive performance of a finite wing oscillating in combined pitch and heave are obtained in closed form. Numerical examples are presented for an elliptic wing.
Ethnically diverse pluripotent stem cells for drug development.
Fakunle, Eyitayo S; Loring, Jeanne F
2012-12-01
Genetic variation is an identified factor underlying drug efficacy and toxicity, and adverse drug reactions, such as liver toxicity, are the primary reasons for post-marketing drug failure. Genetic predisposition to toxicity might be detected early in the drug development pipeline by introducing cell-based assays that reflect the genetic and ethnic variation of the expected treatment population. One challenge for this approach is obtaining a collection of suitable cell lines derived from ethnically diverse populations. Induced pluripotent stem cells (iPSCs) seem ideal for this purpose. They can be obtained from any individual, can be differentiated into multiple relevant cell types, and their self-renewal capability makes it possible to generate large quantities of quality-controlled cell types. Here, we discuss the benefits and challenges of using iPSCs to introduce genetic diversity into the drug development process. Copyright © 2012 Elsevier Ltd. All rights reserved.
Stormwater runoff characterized by GIS determined source areas and runoff volumes.
Liu, Yang; Soonthornnonda, Puripus; Li, Jin; Christensen, Erik R
2011-02-01
Runoff coefficients are usually considered in isolation for each drainage area with resulting large uncertainties in the areas and coefficients. Accurate areas and coefficients are obtained here by optimizing runoff coefficients for characteristic Geographic Information Systems (GIS) subareas within each drainage area so that the resulting runoff coefficients of each drainage area are consistent with those obtained from runoff and rainfall volumes. Lack of fit can indicate that the ArcGIS information is inaccurate or more likely, that the drainage area needs adjustment. Results for 18 drainage areas in Milwaukee, WI for 2000-2004 indicate runoff coefficients ranging from 0.123 for a mostly residential area to 0.679 for a freeway-related land, with a standard error of 0.047. Optimized runoff coefficients are necessary input parameters for monitoring, and for the analysis and design of in situ stormwater unit operations and processes for the control of both urban runoff quantity and quality.
Biofiltration of methanol in an organic biofilter using peanut shells as medium.
Ramirez-Lopez, E M; Corona-Hernandez, J; Avelar-Gonzalez, F J; Omil, F; Thalasso, F
2010-01-01
Biofiltration consists of a filter-bed of organic matter serving both as carrier for the active biomass and as nutrient supply, through which the polluted gas passes. The selection of a suitable medium material is of major importance to ensure optimum biofilter efficiency. Peanut shells are an agricultural byproduct locally available in large quantities at a low price in most tropical and sub-tropical countries. A previous study showed that peanut shells are physically and chemically suitable for biofiltration. This paper presents the results obtained during a six month biofiltration experiment using peanut shells as medium and methanol as air pollutant. It is shown that peanut shells are potentially suitable as biofiltration medium, since degradation rates of up to 30 kg MeOH/m(3)d with an empty bed residence time of 19s was obtained. The biofilter showed a good resistance to shock load and no operational problems were observed.
Proper expression of metabolizable energy in avian energetics
Miller, M.R.; Reinecke, K.J.
1984-01-01
We review metabolizable energy (ME) concepts and present evidence suggesting that the form of ME used for analyses of avian energetics can affect interpretation of results. Apparent ME (AME) is the most widely used measure of food energy available to birds. True ME(TME) differs from AME in recognizing fecal and urinary energy of nonfood origin as metabolized energy. Only AME values obtained from test birds fed at maintenance levels should be used for energy analyses. A practical assay for TME has shown that TME estimates are less sensitive than AME to variation in food intake. The TME assay may be particularly useful in studies of natural foods that are difficult to obtain in quantities large enough to supply test birds with maintenance requirements. Energy budgets calculated from existence metabolism should be expressed as kJ of AME and converted to food requirements with estimates of metabolizability given in kJ AME/g.
Code of Federal Regulations, 2011 CFR
2011-01-01
... quantity or quality of water, or in which such a decline is considered imminent, to obtain or maintain adequate quantities of water that meets the standards set by the Safe Drinking Water Act (42 U.S.C. 300f et... (CONTINUED) EMERGENCY AND IMMINENT COMMUNITY WATER ASSISTANCE GRANTS § 1778.3 Objective. The objective of the...
Increased urbanization results in a larger percentage of connected impervious areas and can contribute large quantities of stormwater runoff and significant quantities of debris and pollutants (e.g., litter, oils, microorganisms, sediments, nutrients, organic matter, and heavy me...
NASA Astrophysics Data System (ADS)
Song, Enzhe; Fan, Liyun; Chen, Chao; Dong, Quan; Ma, Xiuzhen; Bai, Yun
2013-09-01
A simulation model of an electronically controlled two solenoid valve fuel injection system for a diesel engine is established in the AMESim environment. The accuracy of the model is validated through comparison with experimental data. The influence of pre-injection control parameters on main-injection quantity under different control modes is analyzed. In the spill control valve mode, main-injection fuel quantity decreases gradually and then reaches a stable level because of the increase in multi-injection dwell time. In the needle control valve mode, main-injection fuel quantity increases with rising multi-injection dwell time; this effect becomes more obvious at high-speed revolutions and large main-injection pulse widths. Pre-injection pulse width has no obvious influence on main-injection quantity under the two control modes; the variation in main-injection quantity is in the range of 1 mm3.
Do Social Conditions Affect Capuchin Monkeys' (Cebus apella) Choices in a Quantity Judgment Task?
Beran, Michael J; Perdue, Bonnie M; Parrish, Audrey E; Evans, Theodore A
2012-01-01
Beran et al. (2012) reported that capuchin monkeys closely matched the performance of humans in a quantity judgment test in which information was incomplete but a judgment still had to be made. In each test session, subjects first made quantity judgments between two known options. Then, they made choices where only one option was visible. Both humans and capuchin monkeys were guided by past outcomes, as they shifted from selecting a known option to selecting an unknown option at the point at which the known option went from being more than the average rate of return to less than the average rate of return from earlier choices in the test session. Here, we expanded this assessment of what guides quantity judgment choice behavior in the face of incomplete information to include manipulations to the unselected quantity. We manipulated the unchosen set in two ways: first, we showed the monkeys what they did not get (the unchosen set), anticipating that "losses" would weigh heavily on subsequent trials in which the same known quantity was presented. Second, we sometimes gave the unchosen set to another monkey, anticipating that this social manipulation might influence the risk-taking responses of the focal monkey when faced with incomplete information. However, neither manipulation caused difficulty for the monkeys who instead continued to use the rational strategy of choosing known sets when they were as large as or larger than the average rate of return in the session, and choosing the unknown (riskier) set when the known set was not sufficiently large. As in past experiments, this was true across a variety of daily ranges of quantities, indicating that monkeys were not using some absolute quantity as a threshold for selecting (or not) the known set, but instead continued to use the daily average rate of return to determine when to choose the known versus the unknown quantity.
Nebulization Reflux Concentrator
NASA Technical Reports Server (NTRS)
Cofer, Wesley R., III; Collins, V. G.
1986-01-01
Nebulization reflux concentrator extracts and concentrates trace quantities of water-soluble gases for subsequent chemical analysis. Hydrophobic membrane and nebulizing nozzles form scrubber for removing trace quantities of soluble gases or other contaminants from atmosphere. Although hydrophobic membrane virtually blocks all transport of droplets, it offers little resistance to gas flow; hence, device permits relatively large volumes of gas scrubbed efficiently with very small volumes of liquid. This means analyzable quantities of contaminants concentrate in extracting solutions in much shorter times than with conventional techniques.
An ab initio electronic transport database for inorganic materials
Ricci, Francesco; Chen, Wei; Aydemir, Umut; ...
2017-07-04
Electronic transport in materials is governed by a series of tensorial properties such as conductivity, Seebeck coefficient, and effective mass. These quantities are paramount to the understanding of materials in many fields from thermoelectrics to electronics and photovoltaics. Transport properties can be calculated from a material’s band structure using the Boltzmann transport theory framework. We present here the largest computational database of electronic transport properties based on a large set of 48,000 materials originating from the Materials Project database. Our results were obtained through the interpolation approach developed in the BoltzTraP software, assuming a constant relaxation time. We present themore » workflow to generate the data, the data validation procedure, and the database structure. In conclusion, our aim is to target the large community of scientists developing materials selection strategies and performing studies involving transport properties.« less
NASA Technical Reports Server (NTRS)
Kriegler, F. J.; Christenson, D.; Gordon, M.; Kistler, R.; Lampert, S.; Marshall, R.; Mclaughlin, R.
1974-01-01
The Midas System is a third-generation, fast, multispectral recognition system able to keep pace with the large quantity and high rates of data acquisition from present and projected sensors. A principal objective of the MIDAS Program is to provide a system well interfaced with the human operator and thus to obtain large overall reductions in turn-around time and significant gains in throughput. The hardware and software generated in Phase I of the overall program are described. The system contains a mini-computer to control the various high-speed processing elements in the data path and a classifier which implements an all-digital prototype multivariate-Gaussian maximum likelihood decision algorithm operating at 2 x 100,000 pixels/sec. Sufficient hardware was developed to perform signature extraction from computer-compatible tapes, compute classifier coefficients, control the classifier operation, and diagnose operation. The MIDAS construction and wiring diagrams are given.
NASA Technical Reports Server (NTRS)
Kriegler, F. J.; Christenson, D.; Gordon, M.; Kistler, R.; Lampert, S.; Marshall, R.; Mclaughlin, R.
1974-01-01
The MIDAS System is a third-generation, fast, multispectral recognition system able to keep pace with the large quantity and high rates of data acquisition from present and projected sensors. A principal objective of the MIDAS Program is to provide a system well interfaced with the human operator and thus to obtain large overall reductions in turn-around time and significant gains in throughout. The hardware and software generated in Phase I of the over-all program are described. The system contains a mini-computer to control the various high-speed processing elements in the data path and a classifier which implements an all-digital prototype multivariate-Gaussian maximum likelihood decision algorithm operating 2 x 105 pixels/sec. Sufficient hardware was developed to perform signature extraction from computer-compatible tapes, compute classifier coefficients, control the classifier operation, and diagnose operation. Diagnostic programs used to test MIDAS' operations are presented.
NASA Technical Reports Server (NTRS)
Nguyen, Truong X.; Dudley, Kenneth L.; Scearce, Stephen A.; Ely, Jay J.; Richardson, Robert E.; Hatfield, Michael O.
2000-01-01
An investigation was performed to study the potential for radio frequency (RF) power radiated from Portable Electronic Devices (PEDs) to create an arcing/sparking event within the fuel tank of a large transport aircraft. This paper describes the experimental methods used for measuring RF coupling to the fuel tank and Fuel Quantity Indication System (FQIS) wiring from PED sources located in the passenger cabin. To allow comparison of voltage/current data obtained in a laboratory chamber FQIS installation to an actual aircraft FQIS installation, aircraft fuel tank RF reverberation characteristics were also measured. Results from the measurements, along with a survey of threats from typical intentional transmitting PEDs are presented. The resulting worst-case power coupled onto fuel tank FQIS wiring is derived. The same approach can be applied to measure RF coupling into various other aircraft systems.
NASA Astrophysics Data System (ADS)
Sabater, David; Arriarán, Sofía; Romero, María Del Mar; Agnelli, Silvia; Remesar, Xavier; Fernández-López, José Antonio; Alemany, Marià
2014-01-01
White adipose tissue (WAT) produces lactate in significant amount from circulating glucose, especially in obesity;Under normoxia, 3T3L1 cells secrete large quantities of lactate to the medium, again at the expense of glucose and proportionally to its levels. Most of the glucose was converted to lactate with only part of it being used to synthesize fat. Cultured adipocytes were largely anaerobic, but this was not a Warburg-like process. It is speculated that the massive production of lactate, is a process of defense of the adipocyte, used to dispose of excess glucose. This way, the adipocyte exports glucose carbon (and reduces the problem of excess substrate availability) to the liver, but the process may be also a mechanism of short-term control of hyperglycemia. The in vivo data obtained from adipose tissue of male rats agree with this interpretation.
Logistics and quality control for DNA sampling in large multicenter studies.
Nederhand, R J; Droog, S; Kluft, C; Simoons, M L; de Maat, M P M
2003-05-01
To study associations between genetic variation and disease, large bio-banks need to be created in multicenter studies. Therefore, we studied the effects of storage time and temperature on DNA quality and quantity in a simulation experiment with storage up to 28 days frozen, at 4 degrees C and at room temperature. In the simulation experiment, the conditions did not influence the amount or quality of DNA to an unsatisfactory level. However, the amount of extracted DNA was decreased in frozen samples and in samples that were stored for > 7 days at room temperature. In a sample of patients from 24 countries of the EUROPA trial obtained by mail with transport times up to 1 month DNA yield and quality were adequate. From these results we conclude that transport of non-frozen blood by ordinary mail is usable and practical for DNA isolation for polymerase chain reaction in clinical and epidemiological studies.
An ab initio electronic transport database for inorganic materials
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ricci, Francesco; Chen, Wei; Aydemir, Umut
Electronic transport in materials is governed by a series of tensorial properties such as conductivity, Seebeck coefficient, and effective mass. These quantities are paramount to the understanding of materials in many fields from thermoelectrics to electronics and photovoltaics. Transport properties can be calculated from a material’s band structure using the Boltzmann transport theory framework. We present here the largest computational database of electronic transport properties based on a large set of 48,000 materials originating from the Materials Project database. Our results were obtained through the interpolation approach developed in the BoltzTraP software, assuming a constant relaxation time. We present themore » workflow to generate the data, the data validation procedure, and the database structure. In conclusion, our aim is to target the large community of scientists developing materials selection strategies and performing studies involving transport properties.« less
Relaxation rates of low-field gas-phase ^129Xe storage cells
NASA Astrophysics Data System (ADS)
Limes, Mark; Saam, Brian
2010-10-01
A study of longitudinal nuclear relaxation rates T1 of ^129Xe and Xe-N2 mixtures in a magnetic field of 3.8 mT is presented. In this regime, intrinsic spin relaxation is dominated by the intramolecular spin-rotation interaction due to persistent xenon dimers, a mechanism that can be quelled by introducing large amounts of N2 into the storage cell. Extrinsic spin relaxation is dominated by the wall-relaxation rate, which is the primary quantity of interest for the various low-field storage cells and coatings that we have tested. Previous group work has shown that extremely long gas-phase relaxation times T1 can be obtained, but only at large magnetic fields and low xenon densities. The current work is motivated by the practical benefits of retaining hyperpolarized ^129Xe for extended periods of time in a small magnetic field.
Cocoa Shell: A By-Product with Great Potential for Wide Application.
Panak Balentić, Jelena; Ačkar, Đurđica; Jokić, Stela; Jozinović, Antun; Babić, Jurislav; Miličević, Borislav; Šubarić, Drago; Pavlović, Nika
2018-06-09
Solving the problem of large quantities of organic waste, which represents an enormous ecological and financial burden for all aspects of the process industry, is a necessity. Therefore, there is an emerged need to find specific solutions to utilize raw materials as efficiently as possible in the production process. The cocoa shell is a valuable by-product obtained from the chocolate industry. It is rich in protein, dietary fiber, and ash, as well as in some other valuable bioactive compounds, such as methylxanthines and phenolics. This paper gives an overview of published results related to the cocoa shell, mostly on important bioactive compounds and possible applications of the cocoa shell in different areas. The cocoa shell, due to its nutritional value and high-value bioactive compounds, could become a desirable raw material in a large spectrum of functional, pharmaceutical, or cosmetic products, as well as in the production of energy or biofuels in the near future.
Diffusion with stochastic resetting at power-law times.
Nagar, Apoorva; Gupta, Shamik
2016-06-01
What happens when a continuously evolving stochastic process is interrupted with large changes at random intervals τ distributed as a power law ∼τ^{-(1+α)};α>0? Modeling the stochastic process by diffusion and the large changes as abrupt resets to the initial condition, we obtain exact closed-form expressions for both static and dynamic quantities, while accounting for strong correlations implied by a power law. Our results show that the resulting dynamics exhibits a spectrum of rich long-time behavior, from an ever-spreading spatial distribution for α<1, to one that is time independent for α>1. The dynamics has strong consequences on the time to reach a distant target for the first time; we specifically show that there exists an optimal α that minimizes the mean time to reach the target, thereby offering a step towards a viable strategy to locate targets in a crowded environment.
NASA Astrophysics Data System (ADS)
Xiao, Suo; Liu, Songhang; Zhang, Jianqiu; Wang, Yong
2015-10-01
Environmental pollution and energy deficiency are two key issues for the sustainable development of the modern society. Polyurethane foam is a typical commercial polymer with a large production quantity and its waste needs to be recycled. Lithium-sulfur battery is a promising energy-storage device with high energy density and low cost, but its demerits such as poor conductivity of the sulfur and severe capacity degradation due to the soluble lithium polysulfides are still a big challenge. This work reports a facile method to prepare nitrogen-doped porous carbon (NPC) from the polyurethane foam (PUF) waste and use it as a reservoir to impregnate sulfur for lithium-sulfur batteries. The obtained NPC has a unique interconnected sheet-like porous morphology with a large surface area of 1315 m2 g-1. The NPC-S composite delivers a large reversible capacity of 1118 mAh g-1 with good cycling performances and excellent high-rate capabilities. A large reversible capacity of 460 mAh g-1 can be retained at a large current of 5C (8.35 A g-1) after 100 cycles.
NASA Technical Reports Server (NTRS)
Allen, N. C.
1978-01-01
Implementation of SOLARES will input large quantities of heat continuously into a stationary location on the Earth's surface. The quantity of heat released by each of the SOlARES ground receivers, having a reflector orbit height of 6378 km, exceeds by 30 times that released by large power parks which were studied in detail. Using atmospheric models, estimates are presented for the local weather effects, the synoptic scale effects, and the global scale effects from such intense thermal radiation.
Fast, Dense Low Cost Scintillator for Nuclear Physics
DOE Office of Scientific and Technical Information (OSTI.GOV)
Woody, Craig
2009-07-31
We have studied the morphology, transparency, and optical properties of SrHfO{sub 3}:Ce ceramics. Ceramics can be made transparent by carefully controlling the stoichiometry of the precursor powders. When fully dense, transparent samples can be obtained. Ceramics with a composition close to stoichiometry (Sr:Hf ~ 1) appear to show good transparency and a reasonable light yield several times that of BGO. The contact and distance transparency of ceramics hot-pressed at about 1450ºC is very good, but deteriorates at increasingly higher hot-press temperatures. If these ceramics can be produced in large quantities and sizes, at low cost, they may be of considerablemore » interest for PET and CT.« less
Performance of Air-cooled Engine Cylinders Using Blower Cooling
NASA Technical Reports Server (NTRS)
Schey, Oscar W; Ellerbrock, Herman H , Jr
1936-01-01
An investigation was made to obtain information on the minimum quantity of air and power required to cool conventional air cooled cylinders at various operating conditions when using a blower. The results of these tests show that the minimum power required for satisfactory cooling with an overall blower efficiency of 100 percent varied from 2 to 6 percent of the engine power depending on the operating conditions. The shape of the jacket had a large effect on the cylinder temperatures. Increasing the air speed over the front of the cylinder by keeping the greater part of the circumference of the cylinder covered by the jacket reduced the temperatures over the entire cylinder.
NASA Astrophysics Data System (ADS)
Linbo, GU; Yixi, CAI; Yunxi, SHI; Jing, WANG; Xiaoyu, PU; Jing, TIAN; Runlin, FAN
2017-11-01
To explore the effect of the gas source flow rate on the actual diesel exhaust particulate matter (PM), a test bench for diesel engine exhaust purification was constructed, using indirect non-thermal plasma technology. The effects of different gas source flow rates on the quantity concentration, composition, and apparent activation energy of PM were investigated, using an engine exhaust particle sizer and a thermo-gravimetric analyzer. The results show that when the gas source flow rate was large, not only the maximum peak quantity concentrations of particles had a large drop, but also the peak quantity concentrations shifted to smaller particle sizes from 100 nm to 80 nm. When the gas source flow rate was 10 L min-1, the total quantity concentration greatly decreased where the removal rate of particles was 79.2%, and the variation of the different mode particle proportion was obvious. Non-thermal plasma (NTP) improved the oxidation ability of volatile matter as well as that of solid carbon. However, the NTP gas source rate had little effects on oxidation activity of volatile matter, while it strongly influenced the oxidation activity of solid carbon. Considering the quantity concentration and oxidation activity of particles, a gas source flow rate of 10 L min-1 was more appropriate for the purification of particles.
NASA Astrophysics Data System (ADS)
Lesiuk, Michał; Moszynski, Robert
2014-12-01
In this paper we consider the calculation of two-center exchange integrals over Slater-type orbitals (STOs). We apply the Neumann expansion of the Coulomb interaction potential and consider calculation of all basic quantities which appear in the resulting expression. Analytical closed-form equations for all auxiliary quantities have already been known but they suffer from large digital erosion when some of the parameters are large or small. We derive two differential equations which are obeyed by the most difficult basic integrals. Taking them as a starting point, useful series expansions for small parameter values or asymptotic expansions for large parameter values are systematically derived. The resulting expansions replace the corresponding analytical expressions when the latter introduce significant cancellations. Additionally, we reconsider numerical integration of some necessary quantities and present a new way to calculate the integrand with a controlled precision. All proposed methods are combined to lead to a general, stable algorithm. We perform extensive numerical tests of the introduced expressions to verify their validity and usefulness. Advances reported here provide methodology to compute two-electron exchange integrals over STOs for a broad range of the nonlinear parameters and large angular momenta.
The Impact of Work Quality and Quantity on the Development of Career Decision Status
ERIC Educational Resources Information Center
Earl, Joanne K.; Bright, Jim E. H.
2004-01-01
A study is reported that investigates the relationship between career decision status, quantity and quality of work experience obtained by university students. Career decision status is the term used to capture an individual's level of decidedness and comfort with their career decisions and the reasons underlying this state (Jones & Lohmann,…
21 CFR 1303.22 - Procedure for applying for individual manufacturing quotas.
Code of Federal Regulations, 2010 CFR
2010-04-01
... manufacturing quotas. Any person who is registered to manufacture any basic class of controlled substance listed in Schedule I or II and who desires to manufacture a quantity of such class shall apply on DEA Form 189 for a manufacturing quota for such quantity of such class. Copies of DEA Form 189 may be obtained...
Testing of transition-region models: Test cases and data
NASA Technical Reports Server (NTRS)
Singer, Bart A.; Dinavahi, Surya; Iyer, Venkit
1991-01-01
Mean flow quantities in the laminar turbulent transition region and in the fully turbulent region are predicted with different models incorporated into a 3-D boundary layer code. The predicted quantities are compared with experimental data for a large number of different flows and the suitability of the models for each flow is evaluated.
Large-scale generation of cell-derived nanovesicles
NASA Astrophysics Data System (ADS)
Jo, W.; Kim, J.; Yoon, J.; Jeong, D.; Cho, S.; Jeong, H.; Yoon, Y. J.; Kim, S. C.; Gho, Y. S.; Park, J.
2014-09-01
Exosomes are enclosed compartments that are released from cells and that can transport biological contents for the purpose of intercellular communications. Research into exosomes is hindered by their rarity. In this article, we introduce a device that uses centrifugal force and a filter with micro-sized pores to generate a large quantity of cell-derived nanovesicles. The device has a simple polycarbonate structure to hold the filter, and operates in a common centrifuge. Nanovesicles are similar in size and membrane structure to exosomes. Nanovesicles contain intracellular RNAs ranging from microRNA to mRNA, intracellular proteins, and plasma membrane proteins. The quantity of nanovesicles produced using the device is 250 times the quantity of naturally secreted exosomes. Also, the quantity of intracellular contents in nanovesicles is twice that in exosomes. Nanovesicles generated from murine embryonic stem cells can transfer RNAs to target cells. Therefore, this novel device and the nanovesicles that it generates are expected to be used in exosome-related research, and can be applied in various applications such as drug delivery and cell-based therapy.
NASA Astrophysics Data System (ADS)
Anthony, Abigail Walker
This research focuses on the relative advantages and disadvantages of using price-based and quantity-based controls for electricity markets. It also presents a detailed analysis of one specific approach to quantity based controls: the SmartAC program implemented in Stockton, California. Finally, the research forecasts electricity demand under various climate scenarios, and estimates potential cost savings that could result from a direct quantity control program over the next 50 years in each scenario. The traditional approach to dealing with the problem of peak demand for electricity is to invest in a large stock of excess capital that is rarely used, thereby greatly increasing production costs. Because this approach has proved so expensive, there has been a focus on identifying alternative approaches for dealing with peak demand problems. This research focuses on two approaches: price based approaches, such as real time pricing, and quantity based approaches, whereby the utility directly controls at least some elements of electricity used by consumers. This research suggests that well-designed policies for reducing peak demand might include both price and quantity controls. In theory, sufficiently high peak prices occurring during periods of peak demand and/or low supply can cause the quantity of electricity demanded to decline until demand is in balance with system capacity, potentially reducing the total amount of generation capacity needed to meet demand and helping meet electricity demand at the lowest cost. However, consumers need to be well informed about real-time prices for the pricing strategy to work as well as theory suggests. While this might be an appropriate assumption for large industrial and commercial users who have potentially large economic incentives, there is not yet enough research on whether households will fully understand and respond to real-time prices. Thus, while real-time pricing can be an effective tool for addressing the peak load problems, pricing approaches are not well suited to ensure system reliability. This research shows that direct quantity controls are better suited for avoiding catastrophic failure that results when demand exceeds supply capacity.
Piskulich, Zeke A; Mesele, Oluwaseun O; Thompson, Ward H
2017-10-07
General approaches for directly calculating the temperature dependence of dynamical quantities from simulations at a single temperature are presented. The method is demonstrated for self-diffusion and OH reorientation in liquid water. For quantities which possess an activation energy, e.g., the diffusion coefficient and the reorientation time, the results from the direct calculation are in excellent agreement with those obtained from an Arrhenius plot. However, additional information is obtained, including the decomposition of the contributions to the activation energy. These results are discussed along with prospects for additional applications of the direct approach.
Condensation and critical exponents of an ideal non-Abelian gas
NASA Astrophysics Data System (ADS)
Talaei, Zahra; Mirza, Behrouz; Mohammadzadeh, Hosein
2017-11-01
We investigate an ideal gas obeying non-Abelian statistics and derive the expressions for some thermodynamic quantities. It is found that thermodynamic quantities are finite at the condensation point where their derivatives diverge and, near this point, they behave as \\vert T-Tc\\vert^{-ρ} in which Tc denotes the condensation temperature and ρ is a critical exponent. The critical exponents related to the heat capacity and compressibility are obtained by fitting numerical results and others are obtained using the scaling law hypothesis for a three-dimensional non-Abelian ideal gas. This set of critical exponents introduces a new universality class.
Particle number dependence in the non-linear evolution of N-body self-gravitating systems
NASA Astrophysics Data System (ADS)
Benhaiem, D.; Joyce, M.; Sylos Labini, F.; Worrakitpoonpon, T.
2018-01-01
Simulations of purely self-gravitating N-body systems are often used in astrophysics and cosmology to study the collisionless limit of such systems. Their results for macroscopic quantities should then converge well for sufficiently large N. Using a study of the evolution from a simple space of spherical initial conditions - including a region characterized by so-called 'radial orbit instability' - we illustrate that the values of N at which such convergence is obtained can vary enormously. In the family of initial conditions we study, good convergence can be obtained up to a few dynamical times with N ∼ 103 - just large enough to suppress two body relaxation - for certain initial conditions, while in other cases such convergence is not attained at this time even in our largest simulations with N ∼ 105. The qualitative difference is due to the stability properties of fluctuations introduced by the N-body discretisation, of which the initial amplitude depends on N. We discuss briefly why the crucial role which such fluctuations can potentially play in the evolution of the N body system could, in particular, constitute a serious problem in cosmological simulations of dark matter.
First principles calculation of finite temperature magnetism in Fe and Fe3C
NASA Astrophysics Data System (ADS)
Eisenbach, M.; Nicholson, D. M.; Rusanu, A.; Brown, G.
2011-04-01
Density functional calculations have proven to be a useful tool in the study of ground state properties of many materials. The investigation of finite temperature magnetism, on the other hand, has to rely usually on the usage of empirical models that allow the large number of evaluations of the systems Hamiltonian that are required to obtain the phase space sampling needed to obtain the free energy, specific heat, magnetization, susceptibility, and other quantities as function of temperature. We have demonstrated a solution to this problem that harnesses the computational power of today's large massively parallel computers by combining a classical Wang-Landau Monte-Carlo calculation [F. Wang and D. P. Landau, Phys. Rev. Lett. 86, 2050 (2001)] with our first principles multiple scattering electronic structure code [Y. Wang et al., Phys. Rev. Lett. 75, 2867 (1995)] that allows the energy calculation of constrained magnetic states [M. Eisenbach et al., Proceedings of the Conference on High Performance Computing, Networking, Storage and Analysis (ACM, New York, 2009)]. We present our calculations of finite temperature properties of Fe and Fe3C using this approach and we find the Curie temperatures to be 980 and 425K, respectively.
The chromograph, a new analytical tool for laboratory and field use
Stevens, Rollin Elbert; Lakin, Hubert William
1949-01-01
Water supplies in the Greater Atlanta Region, Georgia, are obtained mainly from surface-water sources, but there is concern that these sources may be unable to meet rising demands. This study indicates that large quantities of good-quality ground water are obtainable from selected sites in the crystalline rocks of the area. Hydrogeologic investigations of 1,051 wells that produce 20 to nearly 500 gallons per minute revealed that large supplies can be developed where favorable structural, stratigraphic, and topographic features result in localized increases in bedrock permeability. These features are described in detail and methods are presented for using them in selecting sites for locating high-producing wells. Most of the site-selection methods are applicable to the north half of the report area, which has rectangular and trellis drainage systems, but their use is restricted in the south half where a dendritic drainage system predominates. Borehole geophysical logs and core drilling revealed that some of the highest production wells derive water from 1- to 8-inch wide horizontal fractures. These fractures occur in a variety of topographic settings and are believed to be stress-relief fractures. (USGS)
NASA Astrophysics Data System (ADS)
Fedi, Filippo; Miglietta, Maria Lucia; Polichetti, Tiziana; Ricciardella, Filiberto; Massera, Ettore; Ninno, Domenico; Di Francia, Girolamo
2015-03-01
Straightforward methods to produce pristine graphene flakes in large quantities are based on the liquid-phase exfoliation processes. These one-step physical transformations of graphite into graphene offer many unique advantages. To date, a large number of liquids have been employed as exfoliation media exploiting their thermodynamic and chemical features as compared to those of graphene. Here, we pursued the goal of realizing water based mixtures to exfoliate graphite and disperse graphene without the aid of surfactants. To this aim, aqueous mixtures with suitable values of surface tension and Hansen solubility parameters (HSPs), were specifically designed and used. The very high water surface tension was decreased by the addition of solvents with lower surface tensions such as alcohols, obtaining, in this way, more favourable HSP distances. The specific role of each of these thermodynamic features was finally investigated. The results showed that the designed hydroalcoholic solutions were effective in both the graphite exfoliation and dispersion without the addition of any surfactants or other stabilizing agents. Stable graphene suspensions were obtained at concentration comparable to those produced with low-boiling solvents and water/surfactants.
Application of sensitivity-analysis techniques to the calculation of topological quantities
NASA Astrophysics Data System (ADS)
Gilchrist, Stuart
2017-08-01
Magnetic reconnection in the corona occurs preferentially at sites where the magnetic connectivity is either discontinuous or has a large spatial gradient. Hence there is a general interest in computing quantities (like the squashing factor) that characterize the gradient in the field-line mapping function. Here we present an algorithm for calculating certain (quasi)topological quantities using mathematical techniques from the field of ``sensitivity-analysis''. The method is based on the calculation of a three dimensional field-line mapping Jacobian from which all the present topological quantities of interest can be derived. We will present the algorithm and the details of a publicly available set of libraries that implement the algorithm.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Romero, Vicente; Bonney, Matthew; Schroeder, Benjamin
When very few samples of a random quantity are available from a source distribution of unknown shape, it is usually not possible to accurately infer the exact distribution from which the data samples come. Under-estimation of important quantities such as response variance and failure probabilities can result. For many engineering purposes, including design and risk analysis, we attempt to avoid under-estimation with a strategy to conservatively estimate (bound) these types of quantities -- without being overly conservative -- when only a few samples of a random quantity are available from model predictions or replicate experiments. This report examines a classmore » of related sparse-data uncertainty representation and inference approaches that are relatively simple, inexpensive, and effective. Tradeoffs between the methods' conservatism, reliability, and risk versus number of data samples (cost) are quantified with multi-attribute metrics use d to assess method performance for conservative estimation of two representative quantities: central 95% of response; and 10 -4 probability of exceeding a response threshold in a tail of the distribution. Each method's performance is characterized with 10,000 random trials on a large number of diverse and challenging distributions. The best method and number of samples to use in a given circumstance depends on the uncertainty quantity to be estimated, the PDF character, and the desired reliability of bounding the true value. On the basis of this large data base and study, a strategy is proposed for selecting the method and number of samples for attaining reasonable credibility levels in bounding these types of quantities when sparse samples of random variables or functions are available from experiments or simulations.« less
How tobacco companies have used package quantity for consumer targeting.
Persoskie, Alexander; Donaldson, Elisabeth A; Ryant, Chase
2018-05-31
Package quantity refers to the number of cigarettes or amount of other tobacco product in a package. Many countries restrict minimum cigarette package quantities to avoid low-cost packs that may lower barriers to youth smoking. We reviewed Truth Tobacco Industry Documents to understand tobacco companies' rationales for introducing new package quantities, including companies' expectations and research regarding how package quantity may influence consumer behaviour. A snowball sampling method (phase 1), a static search string (phase 2) and a follow-up snowball search (phase 3) identified 216 documents, mostly from the 1980s and 1990s, concerning cigarettes (200), roll-your-own tobacco (9), smokeless tobacco (6) and 'smokeless cigarettes' (1). Companies introduced small and large packages to motivate brand-switching and continued use among current users when faced with low market share or threats such as tax-induced price increases or competitors' use of price promotions. Companies developed and evaluated package quantities for specific brands and consumer segments. Large packages offered value-for-money and matched long-term, heavy users' consumption rates. Small packages were cheaper, matched consumption rates of newer and lighter users, and increased products' novelty, ease of carrying and perceived freshness. Some users also preferred small packages as a way to try to limit consumption or quit. Industry documents speculated about many potential effects of package quantity on appeal and use, depending on brand and consumer segment. The search was non-exhaustive, and we could not assess the quality of much of the research or other information on which the documents relied. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
ZnO and ZnTiO3 nanopowders for antimicrobial stone coating
NASA Astrophysics Data System (ADS)
Ruffolo, S. A.; La Russa, M. F.; Malagodi, M.; Oliviero Rossi, C.; Palermo, A. M.; Crisci, G. M.
2010-09-01
In the past a great variety of biocidal compounds and persistent organic pesticides were applied on a large scale for preventive measures aimed at the long-term preservation of our cultural heritage. Only recently, public and expert attention has started to focus increasingly on the risks resulting from these treatments on human health, works of art and environment in general. The work done in this field demonstrated that the most effective way for inactivation can be achieved by using highly efficient photocatalysts with the illumination of UV radiation. Following this direction our group focused its attention on well-known photocatalysts, ZnO and ZnTiO3, in the degradation and complete mineralisation of environmental pollutants. This explorative work deals with an experimental investigation on biocidal efficient of ZnO and ZnTiO3. In particular micro-quantities of the two nanopowdered photocatalysts were spread on plated dishes. They were filled by the MEA (Malt Extract Agar) medium containing given quantities of Aspergillus Niger (a chromogen filamentous fungus involved in biodeterioration). At the same time the two oxides were dispersed in different polymeric matrices, acrylic and fluorinated, in order to obtain a new coating technology, with hydrophobic, consolidant and biocidal properties for the restoration of building stone material. The mixtures obtained were applied on marble samples and capillary water absorption, simulated solar ageing, colourimetric measurements and contact angle measurements have been performed to evaluate its properties.
Property of Fluctuations of Sales Quantities by Product Category in Convenience Stores.
Fukunaga, Gaku; Takayasu, Hideki; Takayasu, Misako
2016-01-01
The ability to ascertain the extent of product sale fluctuations for each store and locality is indispensable to inventory management. This study analyzed POS data from 158 convenience stores in Kawasaki City, Kanagawa Prefecture, Japan and found a power scaling law between the mean and standard deviation of product sales quantities for several product categories. For the statistical domains of low sales quantities, the power index was 1/2; for large sales quantities, the power index was 1, so called Taylor's law holds. The value of sales quantities with changing power indixes differed according to product category. We derived a Poissonian compound distribution model taking into account fluctuations in customer numbers to show that the scaling law could be explained theoretically for most of items. We also examined why the scaling law did not hold in some exceptional cases.
A Functional Model for Management of Large Scale Assessments.
ERIC Educational Resources Information Center
Banta, Trudy W.; And Others
This functional model for managing large-scale program evaluations was developed and validated in connection with the assessment of Tennessee's Nutrition Education and Training Program. Management of such a large-scale assessment requires the development of a structure for the organization; distribution and recovery of large quantities of…
VERY LARGE INTERSTELLAR GRAINS AS EVIDENCED BY THE MID-INFRARED EXTINCTION
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wang, Shu; Jiang, B. W.; Li, Aigen, E-mail: shuwang@mail.bnu.edu.cn, E-mail: bjiang@bnu.edu.cn, E-mail: wanshu@missouri.edu, E-mail: lia@missouri.edu
The sizes of interstellar grains are widely distributed, ranging from a few angstroms to a few micrometers. The ultraviolet (UV) and optical extinction constrains the dust in the size range of a couple hundredths of micrometers to several submicrometers. The near and mid infrared (IR) emission constrains the nanometer-sized grains and angstrom-sized very large molecules. However, the quantity and size distribution of micrometer-sized grains remain unknown because they are gray in the UV/optical extinction and they are too cold and emit too little in the IR to be detected by IRAS, Spitzer, or Herschel. In this work, we employ themore » ∼3–8 μm mid-IR extinction, which is flat in both diffuse and dense regions to constrain the quantity, size, and composition of the μm-sized grain component. We find that, together with nano- and submicron-sized silicate and graphite (as well as polycyclic aromatic hydrocarbons), μm-sized graphite grains with C/H ≈ 137 ppm and a mean size of ∼1.2 μm closely fit the observed interstellar extinction of the Galactic diffuse interstellar medium from the far-UV to the mid-IR, as well as the near-IR to millimeter thermal emission obtained by COBE/DIRBE, COBE/FIRAS, and Planck up to λ ≲ 1000 μm. The μm-sized graphite component accounts for ∼14.6% of the total dust mass and ∼2.5% of the total IR emission.« less
Chemical Waste Management for the Conditionally Exempt Small Quantity Generator
NASA Astrophysics Data System (ADS)
Zimmer, Steven W.
1999-06-01
Management of hazardous chemical wastes generated as a part of the curriculum poses a significant task for the individual responsible for maintaining compliance with all rules and regulations from the Environmental Protection Agency and the Department of Transportation while maintaining the principles of OSHA's Lab Standard and the Hazard Communication Standard. For schools that generate relatively small quantities of waste, an individual can effectively manage the waste program without becoming overly burdened by the EPA regulations required for those generating large quantities of waste, if given the necessary support from the institution.
Production Planning and Simulation for Reverse Supply Chain
NASA Astrophysics Data System (ADS)
Murayama, Takeshi; Yoda, Mitsunobu; Eguchi, Toru; Oba, Fuminori
This paper describes a production planning method for a reverse supply chain, in which a disassembly company takes reusable components from returned used products and supplies the reusable components for a product manufacturer. This method addresses the issue that the timings and quantities of returned products and reusable components obtained from them are unknown. This method first predicts the quantities of returned products and reusable components at each time period by using reliability models. Using the prediction result, the method performs production planning based on Material Requirements Planning (MRP). This method enables us to plan at each time period: the quantity of the products to be disassembled; the quantity of the reusable components to be used; and the quantity of the new components to be produced. The flow of the components and products through a forward and reverse supply chain is simulated to show the effectiveness of the method.
NASA Astrophysics Data System (ADS)
Siripatana, Adil; Mayo, Talea; Sraj, Ihab; Knio, Omar; Dawson, Clint; Le Maitre, Olivier; Hoteit, Ibrahim
2017-08-01
Bayesian estimation/inversion is commonly used to quantify and reduce modeling uncertainties in coastal ocean model, especially in the framework of parameter estimation. Based on Bayes rule, the posterior probability distribution function (pdf) of the estimated quantities is obtained conditioned on available data. It can be computed either directly, using a Markov chain Monte Carlo (MCMC) approach, or by sequentially processing the data following a data assimilation approach, which is heavily exploited in large dimensional state estimation problems. The advantage of data assimilation schemes over MCMC-type methods arises from the ability to algorithmically accommodate a large number of uncertain quantities without significant increase in the computational requirements. However, only approximate estimates are generally obtained by this approach due to the restricted Gaussian prior and noise assumptions that are generally imposed in these methods. This contribution aims at evaluating the effectiveness of utilizing an ensemble Kalman-based data assimilation method for parameter estimation of a coastal ocean model against an MCMC polynomial chaos (PC)-based scheme. We focus on quantifying the uncertainties of a coastal ocean ADvanced CIRCulation (ADCIRC) model with respect to the Manning's n coefficients. Based on a realistic framework of observation system simulation experiments (OSSEs), we apply an ensemble Kalman filter and the MCMC method employing a surrogate of ADCIRC constructed by a non-intrusive PC expansion for evaluating the likelihood, and test both approaches under identical scenarios. We study the sensitivity of the estimated posteriors with respect to the parameters of the inference methods, including ensemble size, inflation factor, and PC order. A full analysis of both methods, in the context of coastal ocean model, suggests that an ensemble Kalman filter with appropriate ensemble size and well-tuned inflation provides reliable mean estimates and uncertainties of Manning's n coefficients compared to the full posterior distributions inferred by MCMC.
Tian, Zi-Qiang; Liu, Jun-Feng; Zhang, Shao-Wei; Li, Bao-Qing; Wang, Fu-Shun; Zhang, Yue-Feng
2004-03-01
Unbuffered formalin is widely used to fix resected specimens in China. The DNA in unbuffered formalin-fixed and paraffin-embedded tissues is usually degraded seriously, so the extraction of DNA from these samples is difficult. This study was conducted to seek an optimal method to extract DNA from these samples. Fifteen blocks of esophageal carcinoma resected in Fourth Hospital of Hebei Medical University in 2000 were selected. The cells were lyzed by proteinase K digestion or heating under different pH values, then DNA was extracted by phenol:chloroform. After that, four parameters (deparaffined by xylene or histolene; digested for 48 h or 72 h at 37 degrees C or 56 degrees C; extracted by salting-out or phenol:chloroform) were optimized according to the principle of cross design. At last, the quality of obtained DNA was analyzed with electrophoresis and PCR amplification. The quality and quantity of DNA obtained by proteinase K digestion (the average yield is 17.88 microg) were better than that of heating under different pH (7-12)(P< 0.05). The quality and quantity of DNA digested at 56 degrees C were better than that at 37 degrees C, and similarly, digestion for 72 hours was better than that for 48 hours. The methods of deparaffin and extraction had no obvious influence on the quality and quantity of DNA. By means of NaCl salting-out after proteinase K digestion, more reliable quality of DNA can be obtained from unbuffered formalin-fixed and paraffin-embedded samples. Furthermore,digestion for three days at 56 degrees C is more likely to obtain DNA with high quality and quantity.
Obtaining and Storing House Sparrow Eggs in Quantity for Nest-Predation Experiments
Richard M. DeGraaf; Thomas J. Maier
2001-01-01
House Sparrow (Passer domesticus) eggs are useful in artificial nest experiments because they are approximately the same size and shell thickness as those of many forest passerines. House Sparrow eggs can be readily collected in quantity by providing nest boxes in active livestock barns. We collected over 1200 eggs in three years (320-567 per year)...
21 CFR 1303.22 - Procedure for applying for individual manufacturing quotas.
Code of Federal Regulations, 2011 CFR
2011-04-01
... in Schedule I or II and who desires to manufacture a quantity of such class shall apply on DEA Form 189 for a manufacturing quota for such quantity of such class. Copies of DEA Form 189 may be obtained... Administration. See the Table of DEA Mailing Addresses in § 1321.01 of this chapter for the current mailing...
1992-12-27
quantities, but they are not continuously dependent on these quantities. This pure open-loop programmed-control-like behaviour is called precognitive . Like...and largely accomplished by the precognitive action and then may be completed with compeisatory eor-reducuon operations. 304. A quasilinear or
Variation of organic matter quantity and quality in streams at Critical Zone Observatory watersheds
Matthew P. Miller; Elizabeth W. Boyer; Diane M. McKnight; Michael G. Brown; Rachel S. Gabor; Carolyn Hunsaker; Lidiia Iavorivska; Shreeram Inamdar; Dale W. Johnson; Louis A. Kaplan; Henry Lin; William H. McDowell; Julia N. Perdrial
2016-01-01
The quantity and chemical composition of dissolved organic matter (DOM) in surface waters influence ecosystem processes and anthropogenic use of freshwater. However, despite the importance of understanding spatial and temporal patterns in DOM, measures of DOM quality are not routinely included as part of large-scale ecosystem monitoring programs and variations in...
Elberson, Benjamin W.; Whisenant, Ty E.; Cortes, D. Marien; Cuello, Luis G.
2017-01-01
The Erwinia chrisanthemi ligand-gated ion channel, ELIC, is considered an excellent structural and functional surrogate for the whole pentameric ligand-gated ion channel family. Despite its simplicity, ELIC is structurally capable of undergoing ligand-dependent activation and a concomitant desensitization process. To determine at the molecular level the structural changes underlying ELIC’s function, it is desirable to produce large quantities of protein. This protein should be properly folded, fully-functional and amenable to structural determinations. In the current paper, we report a completely new protocol for the expression and purification of milligram quantities of fully-functional, more stable and crystallizable ELIC. The use of an autoinduction media and inexpensive detergents during ELIC extraction, in addition to the high-quality and large quantity of the purified channel, are the highlights of this improved biochemical protocol. PMID:28279818
Wester, Dennis W; Steele, Richard T; Rinehart, Donald E; DesChane, Jaquetta R; Carson, Katharine J; Rapko, Brian M; Tenforde, Thomas S
2003-07-01
A major limitation on the supply of the short-lived medical isotope 90Y (t1/2 = 64 h) is the available quantity of highly purified 90Sr generator material. A radiochemical production campaign was therefore undertaken to purify 1,500 Ci of 90Sr that had been isolated from fission waste materials. A series of alkaline precipitation steps removed all detectable traces of 137Cs, alpha emitters, and uranium and transuranic elements. Technical obstacles such as the buildup of gas pressure generated upon mixing large quantities of acid with solid 90Sr carbonate were overcome through safety features incorporated into the custom-built equipment used for 90Sr purification. Methods are described for analyzing the chemical and radiochemical purity of the final product and for accurately determining by gravimetry the quantities of 90Sr immobilized on stainless steel filters for future use.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Garza, Jorge; Nichols, Jeffrey A.; Dixon, David A.
2000-01-15
The Hartree product is analyzed in the context of Kohn-Sham theory. The differential equations that emerge from this theory are solved with the optimized effective potential using the Krieger, Li, and Iafrate approximation, in order to get a local potential as required by the ordinary Kohn-Sham procedure. Because the diagonal terms of the exact exchange energy are included in Hartree theory, it is self-interaction free and the exchange potential has the proper asymptotic behavior. We have examined the impact of this correct asymptotic behavior on local and global properties using this simple model to approximate the exchange energy. Local quantities,more » such as the exchange potential and the average local electrostatic potential are used to examine whether the shell structure in an atom is revealed by this theory. Global quantities, such as the highest occupied orbital energy (related to the ionization potential) and the exchange energy are also calculated. These quantities are contrasted with those obtained from calculations with the local density approximation, the generalized gradient approximation, and the self-interaction correction approach proposed by Perdew and Zunger. We conclude that the main characteristics in an atomic system are preserved with the Hartree theory. In particular, the behavior of the exchange potential obtained in this theory is similar to those obtained within other Kohn-Sham approximations. (c) 2000 American Institute of Physics.« less
NASA Astrophysics Data System (ADS)
Asfarizal; Kasim, Anwar; Gunawarman; Santosa
2017-12-01
Empty Palm bunches of fiber is local ingredient in Indonesia that easy to obtain. Empty Palm bunches of fiber can be obtained from the palm oil industry such as in West Pasaman. The character of the empty Palm bunches of fiber that is strong and pliable has high-potential for particle board. To transform the large quantities of fiber become particles in size 0-10 mm requires a specially designed cut machine. Therefore, the machine is designed in two-stage system that is mechanical system, structure and cutting knife. Components that have been made, assembled and then tested to reveal the ability of the machine to cut. The results showed that the straight back and forth motion cut machine is able to cut out the empty oil palm bunches of fiber with a length 0-1 cm, 2 cm, 8 cm and the surface of the cut is not stringy. The cutting capacity is at a length of 2 cm in the result 24.4 (kg/h) and 8 cm obtained results of up to 84 (kg/h)
A wide angle and high Mach number parabolic equation.
Lingevitch, Joseph F; Collins, Michael D; Dacol, Dalcio K; Drob, Douglas P; Rogers, Joel C W; Siegmann, William L
2002-02-01
Various parabolic equations for advected acoustic waves have been derived based on the assumptions of small Mach number and narrow propagation angles, which are of limited validity in atmospheric acoustics. A parabolic equation solution that does not require these assumptions is derived in the weak shear limit, which is appropriate for frequencies of about 0.1 Hz and above for atmospheric acoustics. When the variables are scaled appropriately in this limit, terms involving derivatives of the sound speed, density, and wind speed are small but can have significant cumulative effects. To obtain a solution that is valid at large distances from the source, it is necessary to account for linear terms in the first derivatives of these quantities [A. D. Pierce, J. Acoust. Soc. Am. 87, 2292-2299 (1990)]. This approach is used to obtain a scalar wave equation for advected waves. Since this equation contains two depth operators that do not commute with each other, it does not readily factor into outgoing and incoming solutions. An approximate factorization is obtained that is correct to first order in the commutator of the depth operators.
Optical selection and collection of DNA fragments
Roslaniec, Mary C.; Martin, John C.; Jett, James H.; Cram, L. Scott
1998-01-01
Optical selection and collection of DNA fragments. The present invention includes the optical selection and collection of large (>.mu.g) quantities of clonable, chromosome-specific DNA from a sample of chromosomes. Chromosome selection is based on selective, irreversible photoinactivation of unwanted chromosomal DNA. Although more general procedures may be envisioned, the invention is demonstrated by processing chromosomes in a conventional flow cytometry apparatus, but where no droplets are generated. All chromosomes in the sample are first stained with at least one fluorescent analytic dye and bonded to a photochemically active species which can render chromosomal DNA unclonable if activated. After passing through analyzing light beam(s), unwanted chromosomes are irradiated using light which is absorbed by the photochemically active species, thereby causing photoinactivation. As desired chromosomes pass this photoinactivation point, the inactivating light source is deflected by an optical modulator; hence, desired chromosomes are not photoinactivated and remain clonable. The selection and photoinactivation processes take place on a microsecond timescale. By eliminating droplet formation, chromosome selection rates 50 times greater than those possible with conventional chromosome sorters may be obtained. Thus, usable quantities of clonable DNA from any source thereof may be collected.
Pelletier, Jennifer E; Schreiber, Liana R N; Laska, Melissa N
2017-07-01
To examine state variation in minimum stocking requirements for Special Supplemental Nutrition Program for Women, Infants, and Children (WIC)-authorized small food retailers. We obtained minimum stocking requirements for 50 states and the District of Columbia in 2017 from WIC Web pages or e-mail from the state WIC agency. We developed a coding protocol to compare minimum quantities and varieties required for 12 food and beverage categories. We calculated the median, range, and interquartile range for each measure. Nearly all states set minimum varieties and quantities of fruits and vegetables, 100% juice, whole grain-rich foods, breakfast cereal, milk, cheese, eggs, legumes, and peanut butter. Fewer states set requirements for canned fish, yogurt, and tofu. Most measures had a large range in minimum requirements (e.g., $8-$100 of fruits and vegetables, 60-144 oz of breakfast cereal). WIC-participating retailers must adhere to very different minimum stocking requirements across states, which may result in disparities in food and beverage products available to WIC recipients. Public Health Implications. The results provide benchmarks that can inform new local, state, and federal program and policy efforts to increase healthy food availability in retail settings.
Pollution monitoring using networks of honey bees
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bromenshenk, J.J.; Dewart, M.L.; Thomas, J.M.
1983-08-01
Each year thousands of chemicals in large quantities are introduced into the global environment and the need for effective methods of monitoring these substances has steadily increased. Most monitoring programs rely upon instrumentation to measure specific contaminants in air, water, or soil. However, it has become apparent that humans and their environment are exposed to complex mixtures of chemicals rather than single entities. As our ability to detect ever smaller quantities of pollutants has increased, the biological significance of these findings has become more uncertain. Also, it is clear that monitoring efforts should shift from short-term studies of easily identifiablemore » sources in localized areas to long-term studies of multiple sources over widespread regions. Our investigations aim at providing better tools to meet these exigencies. Honey bees are discussed as an effective, long-term, self-sustaining system for monitoring environmental impacts. Our results indicate that the use of regional, and possibly national or international, capability can be realized with the aid of beekeepers in obtaining samples and conducting measurements. This approach has the added advantage of public involvement in environmental problem solving and protection of human health and environmental quality.« less
NASA Astrophysics Data System (ADS)
Hendi, S. H.; Dehghani, A.
2015-03-01
In this paper, we obtain topological black hole solutions of third-order Lovelock gravity coupled with two classes of Born-Infeld-type nonlinear electrodynamics with anti-de Sitter asymptotic structure. We investigate geometric and thermodynamics properties of the solutions and obtain conserved quantities of the black holes. We examine the first law of thermodynamics and find that the conserved and thermodynamic quantities of the black hole solutions satisfy the first law of thermodynamics. Finally, we calculate the heat capacity and determinant of the Hessian matrix to evaluate thermal stability in both canonical and grand canonical ensembles. Moreover, we consider the extended phase space thermodynamics to obtain a generalized first law of thermodynamics as well as the extended Smarr formula.
Non-symbolic arithmetic in adults and young children.
Barth, Hilary; La Mont, Kristen; Lipton, Jennifer; Dehaene, Stanislas; Kanwisher, Nancy; Spelke, Elizabeth
2006-01-01
Five experiments investigated whether adults and preschool children can perform simple arithmetic calculations on non-symbolic numerosities. Previous research has demonstrated that human adults, human infants, and non-human animals can process numerical quantities through approximate representations of their magnitudes. Here we consider whether these non-symbolic numerical representations might serve as a building block of uniquely human, learned mathematics. Both adults and children with no training in arithmetic successfully performed approximate arithmetic on large sets of elements. Success at these tasks did not depend on non-numerical continuous quantities, modality-specific quantity information, the adoption of alternative non-arithmetic strategies, or learned symbolic arithmetic knowledge. Abstract numerical quantity representations therefore are computationally functional and may provide a foundation for formal mathematics.
Property of Fluctuations of Sales Quantities by Product Category in Convenience Stores
Fukunaga, Gaku; Takayasu, Hideki; Takayasu, Misako
2016-01-01
The ability to ascertain the extent of product sale fluctuations for each store and locality is indispensable to inventory management. This study analyzed POS data from 158 convenience stores in Kawasaki City, Kanagawa Prefecture, Japan and found a power scaling law between the mean and standard deviation of product sales quantities for several product categories. For the statistical domains of low sales quantities, the power index was 1/2; for large sales quantities, the power index was 1, so called Taylor’s law holds. The value of sales quantities with changing power indixes differed according to product category. We derived a Poissonian compound distribution model taking into account fluctuations in customer numbers to show that the scaling law could be explained theoretically for most of items. We also examined why the scaling law did not hold in some exceptional cases. PMID:27310915
Ward identities and consistency relations for the large scale structure with multiple species
DOE Office of Scientific and Technical Information (OSTI.GOV)
Peloso, Marco; Pietroni, Massimo, E-mail: peloso@physics.umn.edu, E-mail: pietroni@pd.infn.it
2014-04-01
We present fully nonlinear consistency relations for the squeezed bispectrum of Large Scale Structure. These relations hold when the matter component of the Universe is composed of one or more species, and generalize those obtained in [1,2] in the single species case. The multi-species relations apply to the standard dark matter + baryons scenario, as well as to the case in which some of the fields are auxiliary quantities describing a particular population, such as dark matter halos or a specific galaxy class. If a large scale velocity bias exists between the different populations new terms appear in the consistencymore » relations with respect to the single species case. As an illustration, we discuss two physical cases in which such a velocity bias can exist: (1) a new long range scalar force in the dark matter sector (resulting in a violation of the equivalence principle in the dark matter-baryon system), and (2) the distribution of dark matter halos relative to that of the underlying dark matter field.« less
The Automatic Recognition of the Abnormal Sky-subtraction Spectra Based on Hadoop
NASA Astrophysics Data System (ADS)
An, An; Pan, Jingchang
2017-10-01
The skylines, superimposing on the target spectrum as a main noise, If the spectrum still contains a large number of high strength skylight residuals after sky-subtraction processing, it will not be conducive to the follow-up analysis of the target spectrum. At the same time, the LAMOST can observe a quantity of spectroscopic data in every night. We need an efficient platform to proceed the recognition of the larger numbers of abnormal sky-subtraction spectra quickly. Hadoop, as a distributed parallel data computing platform, can deal with large amounts of data effectively. In this paper, we conduct the continuum normalization firstly and then a simple and effective method will be presented to automatic recognize the abnormal sky-subtraction spectra based on Hadoop platform. Obtain through the experiment, the Hadoop platform can implement the recognition with more speed and efficiency, and the simple method can recognize the abnormal sky-subtraction spectra and find the abnormal skyline positions of different residual strength effectively, can be applied to the automatic detection of abnormal sky-subtraction of large number of spectra.
NASA Astrophysics Data System (ADS)
Suryanarayana, Phanish; Pratapa, Phanisri P.; Sharma, Abhiraj; Pask, John E.
2018-03-01
We present SQDFT: a large-scale parallel implementation of the Spectral Quadrature (SQ) method for O(N) Kohn-Sham Density Functional Theory (DFT) calculations at high temperature. Specifically, we develop an efficient and scalable finite-difference implementation of the infinite-cell Clenshaw-Curtis SQ approach, in which results for the infinite crystal are obtained by expressing quantities of interest as bilinear forms or sums of bilinear forms, that are then approximated by spatially localized Clenshaw-Curtis quadrature rules. We demonstrate the accuracy of SQDFT by showing systematic convergence of energies and atomic forces with respect to SQ parameters to reference diagonalization results, and convergence with discretization to established planewave results, for both metallic and insulating systems. We further demonstrate that SQDFT achieves excellent strong and weak parallel scaling on computer systems consisting of tens of thousands of processors, with near perfect O(N) scaling with system size and wall times as low as a few seconds per self-consistent field iteration. Finally, we verify the accuracy of SQDFT in large-scale quantum molecular dynamics simulations of aluminum at high temperature.
NASA Astrophysics Data System (ADS)
Wang, Bo-Zhi; Deng, Biao; Su, Shi-Jun; Ding, Sang-Lan; Sun, Wei-Yi
2018-03-01
Electrolytic manganese is conventionally produced through low-grade manganese ore leaching in SO2, with the combustion of high sulfur coal. Subsequently the coal ash and manganese slag, produced by the combustion of high sulfur coal and preparation of electrolytic manganese, can be used as raw ingredients for the preparation of sulphoaluminate cement. In order to realize the `coal-electricity-sulfur-manganese-building material' system of complementary resource utilization, the conditions of material inflow and outflow in each process were determined using material flow analysis. The material flow models in each unit and process can be obtained by analyzed of material flow for new technology, and the input-output model could be obtained. Through the model, it is possible to obtain the quantity of all the input and output material in the condition of limiting the quantity of a substance. Taking one ton electrolytic manganese as a basis, the quantity of other input material and cements can be determined with the input-output model. The whole system had thusly achieved a cleaner production level. Therefore, the input-output model can be used for guidance in practical production.
NASA Astrophysics Data System (ADS)
Kwak, G.; Kim, K.; Park, Y.
2014-02-01
As the maritime boundary delimitation is important for the purpose of securing marine resources, in addition to the aspect of maritime security, interest in maritime boundary delimitation to help national benefits are increasing over the world. In Korea, the importance of maritime boundary delimitation with the neighbouring countries is also increasing in practice. The quantity of obtainable marine resources depending on maritime boundary acts as an important factor for maritime boundary delimitation. Accordingly, a study is required to calculate quantity of our obtainable marine resources depending on maritime boundary delimitation. This study intends to calculate obtainable marine resources depending on various maritime boundary scenarios insisted by several countries. It mainly aims at developing a GIS-based automation system to be utilized for decision making of the maritime boundary delimitation. For this target, it has designed a module using spatial analysis technique to automatically calculate profit and loss waters area of each country upon maritime boundary and another module to estimate economic profits and losses obtained by each country using the calculated waters area and pricing information of the marine resources. By linking both the designed modules, it has implemented an automatic economic profit and loss calculation system for the GIS-based maritime boundary delimitation. The system developed from this study automatically calculate quantity of the obtainable marine resources of a country for the maritime boundary to be added and created in the future. Thus, it is expected to support decision making for the maritime boundary negotiators.
On the Lagrangian description of dissipative systems
NASA Astrophysics Data System (ADS)
Martínez-Pérez, N. E.; Ramírez, C.
2018-03-01
We consider the Lagrangian formulation with duplicated variables of dissipative mechanical systems. The application of Noether theorem leads to physical observable quantities which are not conserved, like energy and angular momentum, and conserved quantities, like the Hamiltonian, that generate symmetry transformations and do not correspond to observables. We show that there are simple relations among the equations satisfied by these two types of quantities. In the case of the damped harmonic oscillator, from the quantities obtained by the Noether theorem follows the algebra of Feshbach and Tikochinsky. Furthermore, if we consider the whole dynamics, the degrees of freedom separate into a physical and an unphysical sector. We analyze several cases, with linear and nonlinear dissipative forces; the physical consistency of the solutions is ensured, observing that the unphysical sector has always the trivial solution.
Hansen, Mark; Howd, Peter; Sallenger, Asbury; Wright, C. Wayne; Lillycrop, Jeff
2007-01-01
Hurricane Katrina severely impacted coastal Mississippi, creating large quantities of building and vegetation debris. This paper summarizes techniques to estimate vegetation and nonvegetation debris quantities from light detection and ranging (lidar) data and presents debris volume results for Harrison County, Miss.
7 CFR 201.33 - Seed in bulk or large quantities; seed for cleaning or processing.
Code of Federal Regulations, 2014 CFR
2014-01-01
... quantities; seed for cleaning or processing. (a) In the case of seed in bulk, the information required under... seeds. (b) Seed consigned to a seed cleaning or processing establishment, for cleaning or processing for... pertaining to such seed show that it is “Seed for processing,” or, if the seed is in containers and in...
7 CFR 201.33 - Seed in bulk or large quantities; seed for cleaning or processing.
Code of Federal Regulations, 2012 CFR
2012-01-01
... quantities; seed for cleaning or processing. (a) In the case of seed in bulk, the information required under... seeds. (b) Seed consigned to a seed cleaning or processing establishment, for cleaning or processing for... pertaining to such seed show that it is “Seed for processing,” or, if the seed is in containers and in...
7 CFR 201.33 - Seed in bulk or large quantities; seed for cleaning or processing.
Code of Federal Regulations, 2011 CFR
2011-01-01
... quantities; seed for cleaning or processing. (a) In the case of seed in bulk, the information required under... seeds. (b) Seed consigned to a seed cleaning or processing establishment, for cleaning or processing for... pertaining to such seed show that it is “Seed for processing,” or, if the seed is in containers and in...
7 CFR 201.33 - Seed in bulk or large quantities; seed for cleaning or processing.
Code of Federal Regulations, 2010 CFR
2010-01-01
... quantities; seed for cleaning or processing. (a) In the case of seed in bulk, the information required under... seeds. (b) Seed consigned to a seed cleaning or processing establishment, for cleaning or processing for... pertaining to such seed show that it is “Seed for processing,” or, if the seed is in containers and in...
7 CFR 201.33 - Seed in bulk or large quantities; seed for cleaning or processing.
Code of Federal Regulations, 2013 CFR
2013-01-01
... quantities; seed for cleaning or processing. (a) In the case of seed in bulk, the information required under... seeds. (b) Seed consigned to a seed cleaning or processing establishment, for cleaning or processing for... pertaining to such seed show that it is “Seed for processing,” or, if the seed is in containers and in...
A Kinetic Study Using Evaporation of Different Types of Hand-Rub Sanitizers
ERIC Educational Resources Information Center
Pinhas, Allan R.
2010-01-01
Alcohol-based hand-rub sanitizers are the types of products that hospital professionals use very often. These sanitizers can be classified into two major groups: those that contain a large quantity of thickener, and thus are a gel, and those that contain a small quantity of thickener, and thus remain a liquid. In an effort to create a laboratory…
NASA Technical Reports Server (NTRS)
Rothrock, A M; Lee, D W
1932-01-01
Tests were made to determine the effect of the reservoir volume on the discharge pressures in the injection system of the N.A.C.A. spray photography equipment. The data obtained are applicable to the design of a common rail fuel-injection system. The data show that an injection system of the type described can be designed so that not more than full load fuel quantity can be injected into the engine cylinders, and so that the fuel spray characteristics remain constant over a large range of engine speeds. Formulas are presented for computing the volume of the reservoir and the diameter of the discharge orifice.
High-throughput density-functional perturbation theory phonons for inorganic materials
NASA Astrophysics Data System (ADS)
Petretto, Guido; Dwaraknath, Shyam; P. C. Miranda, Henrique; Winston, Donald; Giantomassi, Matteo; van Setten, Michiel J.; Gonze, Xavier; Persson, Kristin A.; Hautier, Geoffroy; Rignanese, Gian-Marco
2018-05-01
The knowledge of the vibrational properties of a material is of key importance to understand physical phenomena such as thermal conductivity, superconductivity, and ferroelectricity among others. However, detailed experimental phonon spectra are available only for a limited number of materials, which hinders the large-scale analysis of vibrational properties and their derived quantities. In this work, we perform ab initio calculations of the full phonon dispersion and vibrational density of states for 1521 semiconductor compounds in the harmonic approximation based on density functional perturbation theory. The data is collected along with derived dielectric and thermodynamic properties. We present the procedure used to obtain the results, the details of the provided database and a validation based on the comparison with experimental data.
Formulation and Characterization of Epoxy Resin Copolymer for Graphite Composites
NASA Technical Reports Server (NTRS)
Keck, F. L.
1983-01-01
Maximum char yield was obtained with a copolymer containing 25% mol fraction DGEBE and 75% mol fraction DGEBA (Epon 828). To achieve the high values (above 40%), a large quantity of catalyst (trimethoxyboroxine) was necessary. Although a graphite laminate 1/8" thick was successfully fabricated, the limited life of the catalyzed epoxy copolymer system precludes commercial application. Char yields of 45% can be achieved with phenolic cured epoxy systems as indicated by data generated under NAS2-10207 contract. A graphite laminate using this type of resin system was fabricated for comparison purposes. The resultant laminate was easier to process and because the graphite prepreg is more stable, the fabrication process could readily be adapted to commercial applications.
Improved synthesis of phosphatidylserine using bio-based solvents, limonene and p-cymene.
Bi, Yan-Hong; Duan, Zhang-Qun; Du, Wen-Ying; Wang, Zhao-Yu
2015-01-01
The bio-based solvents limonene and p-cymene obtained from citrus waste were innovatively employed as the reaction media for enzymatic synthesis of phosphatidylserine. (R)-(+)-Limonene, which is available in large quantities from citrus waste, and its close derivative p-cymene, are promising green solvents. Herein, they were successfully employed as reaction media for enzyme-mediated transphosphatidylation of phosphatidylcholine with L-serine for phosphatidylserine synthesis for the first time. A 95 % yield of phosphatidylserine was achieved after 12 h and the side-reactions (which are the undesirable hydrolysis of phosphatidylcholine and phosphatidylserine) did not happen. This work presents an alternative strategy for preparing phosphatidylserine that possesses obvious advantages over the traditional processes in terms of high efficiency combined with environmental friendliness.
NASA Astrophysics Data System (ADS)
DeGregorio, P.; Lawlor, A.; Dawson, K. A.
2006-04-01
We introduce a new method to describe systems in the vicinity of dynamical arrest. This involves a map that transforms mobile systems at one length scale to mobile systems at a longer length. This map is capable of capturing the singular behavior accrued across very large length scales, and provides a direct route to the dynamical correlation length and other related quantities. The ideas are immediately applicable in two spatial dimensions, and have been applied to a modified Kob-Andersen type model. For such systems the map may be derived in an exact form, and readily solved numerically. We obtain the asymptotic behavior across the whole physical domain of interest in dynamical arrest.
Simple formalism for efficient derivatives and multi-determinant expansions in quantum Monte Carlo
DOE Office of Scientific and Technical Information (OSTI.GOV)
Filippi, Claudia, E-mail: c.filippi@utwente.nl; Assaraf, Roland, E-mail: assaraf@lct.jussieu.fr; Moroni, Saverio, E-mail: moroni@democritos.it
2016-05-21
We present a simple and general formalism to compute efficiently the derivatives of a multi-determinant Jastrow-Slater wave function, the local energy, the interatomic forces, and similar quantities needed in quantum Monte Carlo. Through a straightforward manipulation of matrices evaluated on the occupied and virtual orbitals, we obtain an efficiency equivalent to algorithmic differentiation in the computation of the interatomic forces and the optimization of the orbital parameters. Furthermore, for a large multi-determinant expansion, the significant computational gain afforded by a recently introduced table method is here extended to the local value of any one-body operator and to its derivatives, inmore » both all-electron and pseudopotential calculations.« less
Plant species evaluated for new crop potential
DOE Office of Scientific and Technical Information (OSTI.GOV)
Carr, M.E.
1985-01-01
Ninety-two plant species from various regions of the USA were screened for their energy-producing potential. Samples were analysed for oil, polyphenol, hydrocarbon and protein. Oil fractions of some species were analysed for classes of lipid constituents and yields of unsaponifiable matter and fatty acids were determined. Hydrocarbon fractions of some species were analysed for rubber, gutta and waxes. Average MW and MW distribution of rubber and gutta were determined. Complete analytical data for 16 species is presented. Large quantities of oil were obtained from Philadelphus coronarius, Cacalia muhlenbergii, Lindera benzoin and Koelreuteria paniculata. High yields of polyphenols came from Acermore » ginnala, Cornus obliqua and Salix caprea and maximum yields of hydrocarbon and protein were from Elymus virginicus and Lindera benzoin, respectively.« less
760 nm high-performance VCSEL growth and characterization
NASA Astrophysics Data System (ADS)
Rinaldi, Fernando; Ostermann, Johannes M.; Kroner, Andrea; Riedl, Michael C.; Michalzik, Rainer
2006-04-01
High-performance vertical-cavity surface-emitting lasers (VCSELs) with an emission wavelength of approximately 764 nm are demonstrated. This wavelength is very attractive for oxygen sensing. Low threshold currents, high optical output power, single-mode operation, and stable polarization are obtained. Using the surface relief technique and in particular the grating relief technique, we have increased the single-mode output power to more than 2.5mW averaged over a large device quantity. The laser structure was grown by molecular beam epitaxy (MBE) on GaAs (100)-oriented substrates. The devices are entirely based on the AlGaAs mixed compound semiconductor material system. The growth process, the investigations of the epitaxial material together with the device fabrication and characterization are discussed in detail.
Entanglement of purification in free scalar field theories
NASA Astrophysics Data System (ADS)
Bhattacharyya, Arpan; Takayanagi, Tadashi; Umemoto, Koji
2018-04-01
We compute the entanglement of purification (EoP) in a 2d free scalar field theory with various masses. This quantity measures correlations between two subsystems and is reduced to the entanglement entropy when the total system is pure. We obtain explicit numerical values by assuming minimal gaussian wave functionals for the purified states. We find that when the distance between the subsystems is large, the EoP behaves like the mutual information. However, when the distance is small, the EoP shows a characteristic behavior which qualitatively agrees with the conjectured holographic computation and which is different from that of the mutual information. We also study behaviors of mutual information in purified spaces and violations of monogamy/strong superadditivity.
Large number discrimination by mosquitofish.
Agrillo, Christian; Piffer, Laura; Bisazza, Angelo
2010-12-22
Recent studies have demonstrated that fish display rudimentary numerical abilities similar to those observed in mammals and birds. The mechanisms underlying the discrimination of small quantities (<4) were recently investigated while, to date, no study has examined the discrimination of large numerosities in fish. Subjects were trained to discriminate between two sets of small geometric figures using social reinforcement. In the first experiment mosquitofish were required to discriminate 4 from 8 objects with or without experimental control of the continuous variables that co-vary with number (area, space, density, total luminance). Results showed that fish can use the sole numerical information to compare quantities but that they preferentially use cumulative surface area as a proxy of the number when this information is available. A second experiment investigated the influence of the total number of elements to discriminate large quantities. Fish proved to be able to discriminate up to 100 vs. 200 objects, without showing any significant decrease in accuracy compared with the 4 vs. 8 discrimination. The third experiment investigated the influence of the ratio between the numerosities. Performance was found to decrease when decreasing the numerical distance. Fish were able to discriminate numbers when ratios were 1:2 or 2:3 but not when the ratio was 3:4. The performance of a sample of undergraduate students, tested non-verbally using the same sets of stimuli, largely overlapped that of fish. Fish are able to use pure numerical information when discriminating between quantities larger than 4 units. As observed in human and non-human primates, the numerical system of fish appears to have virtually no upper limit while the numerical ratio has a clear effect on performance. These similarities further reinforce the view of a common origin of non-verbal numerical systems in all vertebrates.
NASA Astrophysics Data System (ADS)
Fradinata, Edy; Marli Kesuma, Zurnila
2018-05-01
Polynomials and Spline regression are the numeric model where they used to obtain the performance of methods, distance relationship models for cement retailers in Banda Aceh, predicts the market area for retailers and the economic order quantity (EOQ). These numeric models have their difference accuracy for measuring the mean square error (MSE). The distance relationships between retailers are to identify the density of retailers in the town. The dataset is collected from the sales of cement retailer with a global positioning system (GPS). The sales dataset is plotted of its characteristic to obtain the goodness of fitted quadratic, cubic, and fourth polynomial methods. On the real sales dataset, polynomials are used the behavior relationship x-abscissa and y-ordinate to obtain the models. This research obtains some advantages such as; the four models from the methods are useful for predicting the market area for the retailer in the competitiveness, the comparison of the performance of the methods, the distance of the relationship between retailers, and at last the inventory policy based on economic order quantity. The results, the high-density retail relationship areas indicate that the growing population with the construction project. The spline is better than quadratic, cubic, and four polynomials in predicting the points indicating of small MSE. The inventory policy usages the periodic review policy type.
Parrish, Audrey E.; Beran, Michael J.
2014-01-01
The context in which food is presented can alter quantity judgments leading to sub-optimal choice behavior. Humans often over-estimate food quantity on the basis of how food is presented. Food appears larger if plated on smaller dishes than larger dishes and liquid volumes appear larger in taller cups than shorter cups. Moreover, smaller but fuller containers are preferred in comparison to larger, but less full containers with a truly larger quantity. Here, we assessed whether similar phenomena occur in chimpanzees. Four chimpanzees chose between two amounts of food presented in different sized containers, a large (2 oz.) and small (1 oz.) cup. When different quantities were presented in the same-sized cups or when the small cup contained the larger quantity, chimpanzees were highly accurate in choosing the larger food amount. However, when different-sized cups contained the same amount of food or the smaller cup contained the smaller amount of food (but looked relatively fuller), the chimpanzees often showed a bias to select the smaller but fuller cup. These findings contribute to our understanding of how quantity estimation and portion judgment is impacted by the surrounding context in which it is presented. PMID:24374384
NASA Astrophysics Data System (ADS)
Daukšys, M.; Klovas, A.; Venčkauskas, L.
2017-09-01
This study mainly lays emphasis on examining the influence of concrete mixture rheological properties on the quality of formed concrete surfaces. Mixture’s fine aggregate change was taken into the consideration. Over the course of concrete mixture preparation the inner ratio of fine aggregate (sand: fraction of 0/1 and 0/4) was changed. The idea was to increase the quantity of fine particles in the total aggregate’s volume therefore quantity of sand (fraction 0/1) was increased. Six different concrete mixture’s compositions were designed as well as three specimens (concrete piles of 1m2 surface area) were casted. Rheological properties of concrete mixtures were analytically obtained and the quality of formed concrete surfaces was evaluated using image analysis method “BetonGUY 2.0”. As can be obtained from the dependence between concrete mixture rheological properties and its formed surface quality, the increase of concrete mixture’s yield stress and plastic viscosity reduces the quantity of air pores on formed concrete surfaces.
The NCI Cohort Consortium is an extramural-intramural partnership formed by the National Cancer Institute to address the need for large-scale collaborations to pool the large quantity of data and biospecimens necessary to conduct a wide range of cancer studies.
27 CFR 40.183 - Record of tobacco products.
Code of Federal Regulations, 2010 CFR
2010-04-01
..., DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO MANUFACTURE OF TOBACCO PRODUCTS, CIGARETTE PAPERS AND TUBES... quantities of all tobacco products, by kind (small cigars-large cigars; small cigarettes-large cigarettes... inventory; (e) Removed subject to tax (itemize large cigars by sale price in accordance with § 40.22, except...
27 CFR 40.183 - Record of tobacco products.
Code of Federal Regulations, 2013 CFR
2013-04-01
..., DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO MANUFACTURE OF TOBACCO PRODUCTS, CIGARETTE PAPERS AND TUBES... quantities of all tobacco products, by kind (small cigars-large cigars; small cigarettes-large cigarettes... inventory; (e) Removed subject to tax (itemize large cigars by sale price in accordance with § 40.22, except...
27 CFR 40.183 - Record of tobacco products.
Code of Federal Regulations, 2011 CFR
2011-04-01
..., DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO MANUFACTURE OF TOBACCO PRODUCTS, CIGARETTE PAPERS AND TUBES... quantities of all tobacco products, by kind (small cigars-large cigars; small cigarettes-large cigarettes... inventory; (e) Removed subject to tax (itemize large cigars by sale price in accordance with § 40.22, except...
NASA Astrophysics Data System (ADS)
Guidi, Giovanni; Scannapieco, Cecilia; Walcher, C. Jakob
2015-12-01
We study the sources of biases and systematics in the derivation of galaxy properties from observational studies, focusing on stellar masses, star formation rates, gas and stellar metallicities, stellar ages, magnitudes and colours. We use hydrodynamical cosmological simulations of galaxy formation, for which the real quantities are known, and apply observational techniques to derive the observables. We also analyse biases that are relevant for a proper comparison between simulations and observations. For our study, we post-process the simulation outputs to calculate the galaxies' spectral energy distributions (SEDs) using stellar population synthesis models and also generate the fully consistent far-UV-submillimetre wavelength SEDs with the radiative transfer code SUNRISE. We compared the direct results of simulations with the observationally derived quantities obtained in various ways, and found that systematic differences in all studied galaxy properties appear, which are caused by: (1) purely observational biases, (2) the use of mass-weighted and luminosity-weighted quantities, with preferential sampling of more massive and luminous regions, (3) the different ways of constructing the template of models when a fit to the spectra is performed, and (4) variations due to different calibrations, most notably for gas metallicities and star formation rates. Our results show that large differences can appear depending on the technique used to derive galaxy properties. Understanding these differences is of primary importance both for simulators, to allow a better judgement of similarities and differences with observations, and for observers, to allow a proper interpretation of the data.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Dorfman, D.
Earthworms can live in soils containing high quantities of mercury, lead, and zinc. The worms (Lumbricus terrestris) concentrate these heavy metals in their tissues. The use of these worms to reduce the quantities of mercury and other heavy metals in soils may be practical. In July, 1993, a preliminary study was made using earthworms and soils with differing amounts of mercury, The quantities were 0.0 grams, 0.5 grams, and 1.0 grams of mercury as mercuric chloride. Earthworms were placed into these soils for two or more weeks, then harvested. The worms were rinsed with deionized water, then dissolved in nitricmore » acid. Each sample was prepared for analysis with the addition of HNO{sub 3}, H{sub 2}SO{sub 4}, potassium permanganate, and hydrozylamine hydrochloride. A Jerome Instrument gold foil analyzer was used to determine levels of mercury after volatilizing the sample with stannous chloride. Worms exposed to contaminated soils remove 50 to 1,400 times as much mercury as do worms in control soils. In a hypothetical case, a site contaminated with one pound of mercury, 1,000 to 45,000 worms would be required to reduce mercury levels to background levels in the soil (about 250 ppb). After harvesting worms in contaminated soil they could be dried (90% of their weight is water), and the mercury regained by chemical processes. Soil conducive to earthworm survival is required. This includes a well aerated loamy soil, proper pH (7.0), and periodic watering and feeding. There are several methods of harvesting worms, including flooding and electricity. Large numbers of worms can be obtained from commercial growers.« less
Deterministically estimated fission source distributions for Monte Carlo k-eigenvalue problems
Biondo, Elliott D.; Davidson, Gregory G.; Pandya, Tara M.; ...
2018-04-30
The standard Monte Carlo (MC) k-eigenvalue algorithm involves iteratively converging the fission source distribution using a series of potentially time-consuming inactive cycles before quantities of interest can be tallied. One strategy for reducing the computational time requirements of these inactive cycles is the Sourcerer method, in which a deterministic eigenvalue calculation is performed to obtain an improved initial guess for the fission source distribution. This method has been implemented in the Exnihilo software suite within SCALE using the SPNSPN or SNSN solvers in Denovo and the Shift MC code. The efficacy of this method is assessed with different Denovo solutionmore » parameters for a series of typical k-eigenvalue problems including small criticality benchmarks, full-core reactors, and a fuel cask. Here it is found that, in most cases, when a large number of histories per cycle are required to obtain a detailed flux distribution, the Sourcerer method can be used to reduce the computational time requirements of the inactive cycles.« less
Need for optimizing catalyst loading for achieving affordable microbial fuel cells.
Singh, Inderjeet; Chandra, Amreesh
2013-08-01
Microbial fuel cell (MFC) technology is a promising technology for electricity production together with simultaneous water treatment. Catalysts play an important role in deciding the MFC performance. In most reports, effect of catalyst - both type and quantity is not optimized. In this paper, synthesis of nanorods of MnO2-catalyst particles for application in Pt-free MFCs is reported. The effect of catalyst loading i.e., weight ratio, with respect to conducting element and binder has been optimized by employing large number of combinations. Using simple theoretical model, it is shown that too high (or low) concentration of catalysts result in loss of MFC performance. The operation of MFC has been investigated using domestic wastewater as source of bio-waste for obtaining real world situation. Maximum power density of ∼61 mW/m(2) was obtained when weight ratio of catalyst and conducting species was 1:1. Suitable reasons are given to explain the outcomes. Copyright © 2013 Elsevier Ltd. All rights reserved.
A Quadtree-gridding LBM with Immersed Boundary for Two-dimension Viscous Flows
NASA Astrophysics Data System (ADS)
Yao, Jieke; Feng, Wenliang; Chen, Bin; Zhou, Wei; Cao, Shikun
2017-07-01
An un-uniform quadtree grids lattice Boltzmann method (LBM) with immersed boundary is presented in this paper. In overlapping for different level grids, temporal and spatial interpolation are necessary to ensure the continuity of physical quantity. In order to take advantage of the equation for temporal and spatial step in the same level grids, equal interval interpolation, which is simple to apply to any refined boundary grids in the LBM, is adopted in temporal and spatial aspects to obtain second-order accuracy. The velocity correction, which can guarantee more preferably no-slip boundary condition than the direct forcing method and the momentum exchange method in the traditional immersed-boundary LBM, is used for solid boundary to make the best of Cartesian grid. In present quadtree-gridding immersed-boundary LBM, large eddy simulation (LES) is adopted to simulate the flows over obstacle in higher Reynolds number (Re). The incompressible viscous flows over circular cylinder are carried out, and a great agreement is obtained.
A high-accuracy optical linear algebra processor for finite element applications
NASA Technical Reports Server (NTRS)
Casasent, D.; Taylor, B. K.
1984-01-01
Optical linear processors are computationally efficient computers for solving matrix-matrix and matrix-vector oriented problems. Optical system errors limit their dynamic range to 30-40 dB, which limits their accuray to 9-12 bits. Large problems, such as the finite element problem in structural mechanics (with tens or hundreds of thousands of variables) which can exploit the speed of optical processors, require the 32 bit accuracy obtainable from digital machines. To obtain this required 32 bit accuracy with an optical processor, the data can be digitally encoded, thereby reducing the dynamic range requirements of the optical system (i.e., decreasing the effect of optical errors on the data) while providing increased accuracy. This report describes a new digitally encoded optical linear algebra processor architecture for solving finite element and banded matrix-vector problems. A linear static plate bending case study is described which quantities the processor requirements. Multiplication by digital convolution is explained, and the digitally encoded optical processor architecture is advanced.
Deterministically estimated fission source distributions for Monte Carlo k-eigenvalue problems
DOE Office of Scientific and Technical Information (OSTI.GOV)
Biondo, Elliott D.; Davidson, Gregory G.; Pandya, Tara M.
The standard Monte Carlo (MC) k-eigenvalue algorithm involves iteratively converging the fission source distribution using a series of potentially time-consuming inactive cycles before quantities of interest can be tallied. One strategy for reducing the computational time requirements of these inactive cycles is the Sourcerer method, in which a deterministic eigenvalue calculation is performed to obtain an improved initial guess for the fission source distribution. This method has been implemented in the Exnihilo software suite within SCALE using the SPNSPN or SNSN solvers in Denovo and the Shift MC code. The efficacy of this method is assessed with different Denovo solutionmore » parameters for a series of typical k-eigenvalue problems including small criticality benchmarks, full-core reactors, and a fuel cask. Here it is found that, in most cases, when a large number of histories per cycle are required to obtain a detailed flux distribution, the Sourcerer method can be used to reduce the computational time requirements of the inactive cycles.« less
NASA Technical Reports Server (NTRS)
Elson, Lee S.; Froidevaux, Lucien
1993-01-01
Fourier analysis has been applied to data obtained from limb viewing instruments on the Upper Atmosphere Research Satellite. A coordinate system rotation facilitates the efficient computation of Fourier transforms in the temporal and longitudinal domains. Fields such as ozone (O3), chlorine monoxide (ClO), temperature, and water vapor have been transformed by this process. The transforms have been inverted to provide maps of these quantities at selected times, providing a method of accurate time interpolation. Maps obtained by this process show evidence of both horizontal and vertical transport of important trace species such as O3 and ClO. An examination of the polar regions indicates that large-scale planetary variations are likely to play a significant role in transporting midstratospheric O3 into the polar regions. There is also evidence that downward transport occurs, providing a means of moving O3 into the polar vortex at lower altitudes. The transforms themselves show the structure and propagation characteristics of wave variations.
High-Yield Synthesis of Stoichiometric Boron Nitride Nanostructures
Nocua, José E.; Piazza, Fabrice; Weiner, Brad R.; ...
2009-01-01
Boron nimore » tride (BN) nanostructures are structural analogues of carbon nanostructures but have completely different bonding character and structural defects. They are chemically inert, electrically insulating, and potentially important in mechanical applications that include the strengthening of light structural materials. These applications require the reliable production of bulk amounts of pure BN nanostructures in order to be able to reinforce large quantities of structural materials, hence the need for the development of high-yield synthesis methods of pure BN nanostructures. Using borazine ( B 3 N 3 H 6 ) as chemical precursor and the hot-filament chemical vapor deposition (HFCVD) technique, pure BN nanostructures with cross-sectional sizes ranging between 20 and 50 nm were obtained, including nanoparticles and nanofibers. Their crystalline structure was characterized by (XRD), their morphology and nanostructure was examined by (SEM) and (TEM), while their chemical composition was studied by (EDS), (FTIR), (EELS), and (XPS). Taken altogether, the results indicate that all the material obtained is stoichiometric nanostructured BN with hexagonal and rhombohedral crystalline structure.« less
NASA Astrophysics Data System (ADS)
Lin, Wei; Chen, Yu-hua; Wang, Ji-yuan; Gao, Hong-sheng; Wang, Ji-jun; Su, Rong-hua; Mao, Wei
2011-04-01
Detection probability is an important index to represent and estimate target viability, which provides basis for target recognition and decision-making. But it will expend a mass of time and manpower to obtain detection probability in reality. At the same time, due to the different interpretation of personnel practice knowledge and experience, a great difference will often exist in the datum obtained. By means of studying the relationship between image features and perception quantity based on psychology experiments, the probability model has been established, in which the process is as following.Firstly, four image features have been extracted and quantified, which affect directly detection. Four feature similarity degrees between target and background were defined. Secondly, the relationship between single image feature similarity degree and perception quantity was set up based on psychological principle, and psychological experiments of target interpretation were designed which includes about five hundred people for interpretation and two hundred images. In order to reduce image features correlativity, a lot of artificial synthesis images have been made which include images with single brightness feature difference, images with single chromaticity feature difference, images with single texture feature difference and images with single shape feature difference. By analyzing and fitting a mass of experiments datum, the model quantitys have been determined. Finally, by applying statistical decision theory and experimental results, the relationship between perception quantity with target detection probability has been found. With the verification of a great deal of target interpretation in practice, the target detection probability can be obtained by the model quickly and objectively.
ERIC Educational Resources Information Center
Papenberg, Martin; Musch, Jochen
2017-01-01
In multiple-choice tests, the quality of distractors may be more important than their number. We therefore examined the joint influence of distractor quality and quantity on test functioning by providing a sample of 5,793 participants with five parallel test sets consisting of items that differed in the number and quality of distractors.…
USDA-ARS?s Scientific Manuscript database
Large quantities of biofuel production are expected from bioenergy crops at a national scale to meet US biofuel goals. It is important to study biomass production of bioenergy crops and the impacts of these crops on water quantity and quality to identify environment-friendly and productive biofeeds...
Facile photoreduction of graphene oxide by an NAD(P)H model: Hantzsch 1,4-dihydropyridine.
Zhang, Hui-Hui; Liu, Qiang; Feng, Ke; Chen, Bin; Tung, Chen-Ho; Wu, Li-Zhu
2012-05-29
To make "clean" reduced GO sheets in high quality and in large scale, a natural reduced nicotinamine adenine dinucleotide NAD(P)H model, Hantzsch 1,4-dihydropyridine (HEH), is used as a mild organic photoreductant in this work. Benefiting from the intense absorption of HEH in the range of 300-420 nm, the graphene oxide (GO) can be readily reduced by HEH under UV light irradiation (λ > 320 nm) to afford single or few-layer reduced graphene oxide at room temperature. Studies on reduction extent reveal that both irradiation time and concentration ratio of HEH to GO are important for effective reduction of GO under UV light. The as-prepared photochemically reduced graphene oxide (PRGO) dispersion is stable without the need for any polymeric or surfactant stabilizers. Simply by extraction treatment, the "clean" PRGO sheets can be obtained in large quantities, and its conductivity approaches to 4680 S·m(-1) that is the highest value reported by photochemical approaches so far.
Forsberg, Björn; Ulander, Johan; Kjellander, Roland
2005-02-08
The effects of ionic size asymmetry on long-range electrostatic interactions in electrolyte solutions are investigated within the primitive model. Using the formalism of dressed ion theory we analyze correlation functions from Monte Carlo simulations and the hypernetted chain approximation for size asymmetric 1:1 electrolytes. We obtain decay lengths of the screened Coulomb potential, effective charges of ions, and effective permittivity of the solution. It is found that the variation of these quantities with the degree of size asymmetry depends in a quite intricate manner on the interplay between the electrostatic coupling and excluded volume effects. In most cases the magnitude of the effective charge of the small ion species is larger than that of the large species; the difference increases with increasing size asymmetry. The effective charges of both species are larger (in absolute value) than the bare ionic charge, except for high asymmetry where the effective charge of the large ions can become smaller than the bare charge.
NASA Astrophysics Data System (ADS)
Mishra, S. K.; Sahithi, V. V. D.; Rao, C. S. P.
2016-09-01
The lot sizing problem deals with finding optimal order quantities which minimizes the ordering and holding cost of product mix. when multiple items at multiple levels with all capacity restrictions are considered, the lot sizing problem become NP hard. Many heuristics were developed in the past have inevitably failed due to size, computational complexity and time. However the authors were successful in the development of PSO based technique namely iterative improvement binary particles swarm technique to address very large capacitated multi-item multi level lot sizing (CMIMLLS) problem. First binary particle Swarm Optimization algorithm is used to find a solution in a reasonable time and iterative improvement local search mechanism is employed to improvise the solution obtained by BPSO algorithm. This hybrid mechanism of using local search on the global solution is found to improve the quality of solutions with respect to time thus IIBPSO method is found best and show excellent results.
Scanning electron microscopy study of adhesion in sea urchin blastulae. M.S. Thesis
NASA Technical Reports Server (NTRS)
Crowther, Susan D.
1988-01-01
The dissociation supernatant (DS) isolated by disaggregating Strongylocentrotus purpuratus blastulae in calcium- and magnesium-free seawater specifically promotes reaggregation of S. purpuratus blastula cells. The purpose of this study was to use scanning electron microscopy to examine the gross morphology of aggregates formed in the presence of DS to see if it resembles adhesion in partially dissociated blastulae. A new reaggregation procedure developed here, using large volumes of cell suspension and a large diameter of rotation, was utilized to obtain sufficient quantities of aggregates for scanning electron microscopy. The results indicate that aggregates formed in the presence of DS resemble partially dissociated intact embryos in terms of the direct cell-cell adhesion observed. DS did not cause aggregation to form as a result of the entrapment of cells in masses of extracellular material. These studies provide the groundwork for further studies using transmission electron microscopy to more precisely define the adhesive contacts made by cells in the presence of the putative adhesion molecules present in DS.
Perturbation of Large Anti-deSitter Black Holes and AdS/CFT Correspondence
NASA Astrophysics Data System (ADS)
Ahmadzadegan, Aida
As the main goal of this thesis, the canonical form of the perturbation metric of anti-de Sitter black holes in four dimensions is derived by choosing the Regge-Wheeler gauge in the standard Schwarzschild coordinates (t, r, theta, ϕ). By assuming the perturbations to be small, the differential equations governing the perturbations are obtained from the equations deltaRmunu(h ) = 0. Then, by taking the limit of m > > R where R is the radius of AdS space, the perturbation metric and field equations of large AdS black holes are found. Finally, under the shadow of AdS/CFT correspondence, these perturbations can be compared to their corresponding three-dimensional theory of fluid dynamics on the dual space, R x S2. Furthermore, by using the definitions of stress-energy tensor and its perturbation, we can find energy density, pressure and shear viscosity which are the quantities we need to describe the behavior of the fluid on the boundary of the AdS space.
Possibilities and limits concerning the substitution of oil by nuclear energy and coal
NASA Astrophysics Data System (ADS)
Penczynski, P.
1981-05-01
The energy situation in West Germany is discussed. About 96% of the crude oil consumed has to be imported. It is pointed out that this situation together with general developments concerning the diminishing petroleum resources of the world will make it necessary to replace the oil with other energy carriers. Coal resources in West Germany are large enough to last for a few hundred years. However, the consumption of coal as energy carrier should not exceed certain limits in connection with ecological considerations. Uranium as raw material for nuclear energy must also be imported. However, the quantities involved are very small, in connection with the high-energy density of the material. Consequently, a storage of uranium corresponding to a large amount of energy does not present any problems. Various approaches for replacing oil are discussed, taking into account the heat pump, possibilities for storing electric energy generated during the night, automobiles operated with electric energy, energy carriers obtained from coal, and the direct use of coal.
Wafer scale fabrication of carbon nanotube thin film transistors with high yield
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tian, Boyuan; Liang, Xuelei, E-mail: liangxl@pku.edu.cn, E-mail: ssxie@iphy.ac.cn; Yan, Qiuping
Carbon nanotube thin film transistors (CNT-TFTs) are promising candidates for future high performance and low cost macro-electronics. However, most of the reported CNT-TFTs are fabricated in small quantities on a relatively small size substrate. The yield of large scale fabrication and the performance uniformity of devices on large size substrates should be improved before the CNT-TFTs reach real products. In this paper, 25 200 devices, with various geometries (channel width and channel length), were fabricated on 4-in. size ridged and flexible substrates. Almost 100% device yield were obtained on a rigid substrate with high out-put current (>8 μA/μm), high on/off current ratiomore » (>10{sup 5}), and high mobility (>30 cm{sup 2}/V·s). More importantly, uniform performance in 4-in. area was achieved, and the fabrication process can be scaled up. The results give us more confidence for the real application of the CNT-TFT technology in the near future.« less
Thermodynamics of water structural reorganization due to geometric confinement
NASA Astrophysics Data System (ADS)
Stroberg, Wylie; Lichter, Seth
2015-03-01
Models of aqueous solvation have successfully quantified the behavior of water near convex bodies. However, many important processes occurring in aqueous solution involve interactions between solutes and surfaces with complicated non-convex geometries. Examples include the folding of proteins, hydrophobic association of solutes, ligand-receptor binding, and water confined within nanotubes and pores. For these geometries, models for solvation of convex bodies fail to account for the added interactions associated with structural confinement. Due to water's propensity to form networks of hydrogen bonds, small alterations to the confining geometry can induce large structural rearrangement within the water. We perform systematic Monte Carlo simulations of water confined to cylindrical cavities of varying aspect ratio to investigate how small geometric changes to the confining geometry may cause large changes to the structure and thermodynamic state of water. Using the Wang-Landau algorithm, we obtain free energies, enthalpies, entropies, and heat capacities across a broad range of temperatures, and show how these quantities are influenced by the structural rearrangement of water molecules due to geometric perturbations.
Eastern Colorado mobility study : final report
DOT National Transportation Integrated Search
2002-04-01
Colorado, with an economy based in large part on agriculture, has a need to transport large quantities of commodities. The rapidly growing urban areas in the state also need many products and goods to support the growth. Furthermore, Colorado is stra...
Free-ranging dogs assess the quantity of opponents in intergroup conflicts.
Bonanni, Roberto; Natoli, Eugenia; Cafazzo, Simona; Valsecchi, Paola
2011-01-01
In conflicts between social groups, the decision of competitors whether to attack/retreat should be based on the assessment of the quantity of individuals in their own and the opposing group. Experimental studies on numerical cognition in animals suggest that they may represent both large and small numbers as noisy mental magnitudes subject to scalar variability, and small numbers (≤4) also as discrete object-files. Consequently, discriminating between large quantities, but not between smaller ones, should become easier as the asymmetry between quantities increases. Here, we tested these hypotheses by recording naturally occurring conflicts in a population of free-ranging dogs, Canis lupus familiaris, living in a suburban environment. The overall probability of at least one pack member approaching opponents aggressively increased with a decreasing ratio of the number of rivals to that of companions. Moreover, the probability that more than half of the pack members withdrew from a conflict increased when this ratio increased. The skill of dogs in correctly assessing relative group size appeared to improve with increasing the asymmetry in size when at least one pack comprised more than four individuals, and appeared affected to a lesser extent by group size asymmetries when dogs had to compare only small numbers. These results provide the first indications that a representation of quantity based on noisy mental magnitudes may be involved in the assessment of opponents in intergroup conflicts and leave open the possibility that an additional, more precise mechanism may operate with small numbers.
Glycine glycinium picrate—Reinvestigation of the structure and vibrational spectra
NASA Astrophysics Data System (ADS)
Ghazaryan, V. V.; Fleck, M.; Petrosyan, A. M.
2011-01-01
The crystal of diglycine picrate (glycine glycinum picrate) has been obtained from an aqueous solution containing stoichiometric quantities of the components. The species crystallizes in the monoclinic system (space group P2 1/ c). The crystal structure was determined with high accuracy, IR and Raman spectra are discussed and compared with previous results, and the molecular structure is presented. It was shown that crystals of diglycine picrate obtained from the solution containing equimolar quantities may contain picric acid as impurity, which is the reason for the previously reported observation of second harmonic generation in this centrosymmetric crystal. With this example we want to point out the risk of misinterpretation of SHG signals in general.
NASA Astrophysics Data System (ADS)
Vasanth, K. R.; Hanumagowda, B. N.; Santhosh Kumar, J.
2018-04-01
Squeeze film investigations focus upon film pressure, load bearing quantity and the minimum thickness of film. The combined effect of pressure viscous dependent and non- Newtonian couple stress in porous annular plate is studied. The modified equations of one dimensional pressure, load bearing quantity, non dimensional squeeze time are obtained. The conclusions obtained in the study are found to be in very good agreement compared to the previous results which are published. The load carrying capacity is increased due to the variation in the pressure dependent viscosity and also due to the couple stress effect. Finally this results in change in the squeeze film timings.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mezei, Márk
A global quench is an interesting setting where we can study thermalization of subsystems in a pure state. We investigate entanglement entropy (EE) growth in global quenches in holographic field theories and relate some of its aspects to quantities characterizing chaos. More specifically we obtain four key results: 1. We prove holographic bounds on the entanglement velocity vE and the butterfly effect speed vB that arises in the study of chaos. 2. We obtain the EE as a function of time for large spherical entangling surfaces analytically. We show that the EE is insensitive to the details of the initialmore » state or quench protocol. 3. In a thermofield double state we determine analytically the two-sided mutual information between two large concentric spheres separated in time. 4. We derive a bound on the rate of growth of EE for arbitrary shapes, and develop an expansion for EE at early times. In a companion paper, these results are put in the broader context of EE growth in chaotic systems: we relate EE growth to the chaotic spreading of operators, derive bounds on EE at a given time, and compare the holographic results to spin chain numerics and toy models. In this paper, we perform holographic calculations that provide the basis of arguments presented in that paper.« less
On entanglement spreading from holography
Mezei, Márk
2017-05-11
A global quench is an interesting setting where we can study thermalization of subsystems in a pure state. We investigate entanglement entropy (EE) growth in global quenches in holographic field theories and relate some of its aspects to quantities characterizing chaos. More specifically we obtain four key results: 1. We prove holographic bounds on the entanglement velocity vE and the butterfly effect speed vB that arises in the study of chaos. 2. We obtain the EE as a function of time for large spherical entangling surfaces analytically. We show that the EE is insensitive to the details of the initialmore » state or quench protocol. 3. In a thermofield double state we determine analytically the two-sided mutual information between two large concentric spheres separated in time. 4. We derive a bound on the rate of growth of EE for arbitrary shapes, and develop an expansion for EE at early times. In a companion paper, these results are put in the broader context of EE growth in chaotic systems: we relate EE growth to the chaotic spreading of operators, derive bounds on EE at a given time, and compare the holographic results to spin chain numerics and toy models. In this paper, we perform holographic calculations that provide the basis of arguments presented in that paper.« less
Chatrchyan, Serguei
2014-07-23
Dijet production has been measured in pPb collisions at a nucleon-nucleon centre-of-mass energy of 5.02 TeV. A data sample corresponding to an integrated luminosity of 35 inverse-nanobarns was collected using the Compact Muon Solenoid detector at the Large Hadron Collider. The dijet transverse momentum balance, azimuthal angle correlations, and pseudorapidity distributions are studied as a function of the transverse energy in the forward calorimeters (more » $$E_T^{4\\lt |\\eta| \\lt 5.2}$$). For pPb collisions, the dijet transverse momentum ratio and the width of the distribution of dijet azimuthal angle difference are comparable to the same quantities obtained from a simulated pp reference and insensitive to $$E_T^{4\\lt |\\eta| \\lt 5.2}$$. In contrast, the mean value of the dijet pseudorapidity is found to change monotonically with increasing $$E_T^{4\\lt |\\eta| \\lt 5.2}$$, indicating a correlation between the energy emitted at large pseudorapidity and the longitudinal motion of the dijet frame. As a result, the pseudorapidity distribution of the dijet system is compared with next-to-leading-order perturbative QCD predictions obtained from both nucleon and nuclear parton distribution functions, and the data more closely match the latter.« less
Fan, T W; Lane, A N; Pedler, J; Crowley, D; Higashi, R M
1997-08-15
Root exudates in the rhizosphere are vital to the normal life cycle of plants. A key factor is phytometallophores, which function in the nutritional acquisition of iron and zinc and are likely to be important in the uptake of pollutant metals by plants. Unraveling the biochemistry of these compounds is tedious using traditional analyses, which also fall short in providing the overall chemical composition or in detecting unknown or unexpected organic ligands in the exudates. Here, we demonstrate a comprehensive analysis of the exudate composition directly by 1H and 13C multidimensional NMR and silylation GC-MS. The advantages are (a) minimal sample preparation, with no loss of unknown compounds, and reduced net analysis time; (b) structure-based analysis for universal detection and identification; and (c) simultaneous analysis of a large number of constituents in a complex mixture. Using barley root exudates, a large number of common organic and amino acids were identified. Three derivatives of mugineic acid phytosiderophores were also determined, the major one being 3-epihydroxymugineic acid, for which complete 1H and 13C NMR assignments were obtained. Quantification of all major components using these methods revealed a sevenfold increase in total exudation under moderate iron deficiency, with 3-epihydroxymugineic acid comprising approximately 22% of the exudate mixture. As iron deficiency increased, total quantities of exudate per gram of root remained unchanged, but the relative quantity of carbon allocated to phytosiderophore increased to approximately 50% of the total exudate in response to severe iron deficiency.
Splitting of the weak hypercharge quantum
NASA Astrophysics Data System (ADS)
Nielsen, H. B.; Brene, N.
1991-08-01
The ratio between the weak hypercharge quantum for particles having no coupling to the gauge bosons corresponding to the semi-simple component of the gauge group and the smallest hypercharge quantum for particles that do have such couplings is exceptionally large for the standard model, considering its rank. To compare groups with respect to this property we propose a quantity χ which depends on the rank of the group and the splitting ratio of the hypercharge(s) to be found in the group. The quantity χ has maximal value for the gauge group of the standard model. This suggests that the hypercharge splitting may play an important rôle either in the origin of the gauge symmetry at a fundamental scale or in some kind of selection mechanism at a scale perhaps nearer to the experimental scale. Such a selection mechanism might be what we have called confusion which removes groups with many (so-called generalized) automorphisms. The quantity χ tends to be large for groups with few generalized automorphisms.
Quantities of Arsenic-Treated Wood in Demolition Debris Generated by Hurricane Katrina
Dubey, Brajesh; Solo-Gabriele, Helena M.; Townsend, Timothy G.
2008-01-01
The disaster debris from Hurricane Katrina is one of the largest in terms of volume and economic loss in American history. One of the major components of the demolition debris is wood waste of which a significant proportion is treated with preservatives, including preservatives containing arsenic. As a result of the large scale destruction of treated wood structures such as electrical poles, fences, decks, and homes a considerable amount of treated wood and consequently arsenic will be disposed as disaster debris. In this study an effort was made to estimate the quantity of arsenic disposed through demolition debris generated in the Louisiana and Mississippi area through Hurricane Katrina. Of the 72 million cubic meters of disaster debris generated, roughly 12 million cubic meters were in the form of construction and demolition wood resulting in an estimated 1740 metric tons of arsenic disposed. Management of disaster debris should consider the relatively large quantities of arsenic associated with pressure-treated wood. PMID:17396637
A Improved and Highly Effective Seabed Surface Sand Sampling Device
NASA Astrophysics Data System (ADS)
Liu, Ying
2017-04-01
In marine geology research, it is necessary to obtain a sufficient quantity of seabed surface samples, while also ensuring that the samples are in their original state. Currently, there are a number of seabed surface sampling devices available, but it is very difficult to obtain sand samples using ordinary seabed surface sampling devices, whereas machine-controlled seabed surface sampling devices are unable to dive into deeper regions of water. To obtain larger quantities of samples in their original states, many researchers have tried to improve seabed surface sampling devices, but these efforts have generally produced ambiguous results. To resolve the aforementioned issue, we have designed an improved and highly effective seabed surface sand sampling device, which incorporates the strengths of a variety of sampling devices; it is capable of diving into deeper water regions to obtain sand samples, and is also suited for use in streams, rivers, lakes and seas with varying levels of flow velocities and depth.
Large trees losing out to drought
Michael G. Ryan
2015-01-01
Large trees provide many ecological services in forests. They provide seeds for reproduction and food, habitat for plants and animals, and shade for understory vegetation. Older trees and forests store large quantities of carbon, tend to release more water to streams than their more rapidly growing younger counterparts, and provide wood for human use. Mature...
Birdwell, Justin E.
2017-01-01
Oil shales are fine-grained sedimentary rocks formed in many different depositional environments (terrestrial, lacustrine, marine) containing large quantities of thermally immature organic matter in the forms of kerogen and bitumen. If defined from an economic standpoint, a rock containing a sufficient concentration of oil-prone kerogen to generate economic quantities of synthetic crude oil upon heating to high temperatures (350–600 °C) in the absence of oxygen (pyrolysis) can be considered an oil shale.
A Semi-Vectorization Algorithm to Synthesis of Gravitational Anomaly Quantities on the Earth
NASA Astrophysics Data System (ADS)
Abdollahzadeh, M.; Eshagh, M.; Najafi Alamdari, M.
2009-04-01
The Earth's gravitational potential can be expressed by the well-known spherical harmonic expansion. The computational time of summing up this expansion is an important practical issue which can be reduced by an efficient numerical algorithm. This paper proposes such a method for block-wise synthesizing the anomaly quantities on the Earth surface using vectorization. Fully-vectorization means transformation of the summations to the simple matrix and vector products. It is not a practical for the matrices with large dimensions. Here a semi-vectorization algorithm is proposed to avoid working with large vectors and matrices. It speeds up the computations by using one loop for the summation either on degrees or on orders. The former is a good option to synthesize the anomaly quantities on the Earth surface considering a digital elevation model (DEM). This approach is more efficient than the two-step method which computes the quantities on the reference ellipsoid and continues them upward to the Earth surface. The algorithm has been coded in MATLAB which synthesizes a global grid of 5â²Ã- 5â² (corresponding 9 million points) of gravity anomaly or geoid height using a geopotential model to degree 360 in 10000 seconds by an ordinary computer with 2G RAM.
Foster, Stephen P; Anderson, Karin G; Casas, Jérôme
2018-05-10
Moths are exemplars of chemical communication, especially with regard to specificity and the minute amounts they use. Yet, little is known about how females manage synthesis and storage of pheromone to maintain release rates attractive to conspecific males and why such small amounts are used. We developed, for the first time, a quantitative model, based on an extensive empirical data set, describing the dynamical relationship among synthesis, storage (titer) and release of pheromone over time in a moth (Heliothis virescens). The model is compartmental, with one major state variable (titer), one time-varying (synthesis), and two constant (catabolism and release) rates. The model was a good fit, suggesting it accounted for the major processes. Overall, we found the relatively small amounts of pheromone stored and released were largely a function of high catabolism rather than a low rate of synthesis. A paradigm shift may be necessary to understand the low amounts released by female moths, away from the small quantities synthesized to the (relatively) large amounts catabolized. Future research on pheromone quantity should focus on structural and physicochemical processes that limit storage and release rate quantities. To our knowledge, this is the first time that pheromone gland function has been modeled for any animal.
Sequential monitoring of beach litter using webcams.
Kako, Shin'ichiro; Isobe, Atsuhiko; Magome, Shinya
2010-05-01
This study attempts to establish a system for the sequential monitoring of beach litter using webcams placed at the Ookushi beach, Goto Islands, Japan, to establish the temporal variability in the quantities of beach litter every 90 min over a one and a half year period. The time series of the quantities of beach litter, computed by counting pixels with a greater lightness than a threshold value in photographs, shows that litter does not increase monotonically on the beach, but fluctuates mainly on a monthly time scale or less. To investigate what factors influence this variability, the time derivative of the quantity of beach litter is compared with satellite-derived wind speeds. It is found that the beach litter quantities vary largely with winds, but there may be other influencing factors. (c) 2010 Elsevier Ltd. All rights reserved.
Seafood prices reveal impacts of a major ecological disturbance
Smith, Martin D.; Oglend, Atle; Kirkpatrick, A. Justin; Asche, Frank; Bennear, Lori S.; Craig, J. Kevin; Nance, James M.
2017-01-01
Coastal hypoxia (dissolved oxygen ≤ 2 mg/L) is a growing problem worldwide that threatens marine ecosystem services, but little is known about economic effects on fisheries. Here, we provide evidence that hypoxia causes economic impacts on a major fishery. Ecological studies of hypoxia and marine fauna suggest multiple mechanisms through which hypoxia can skew a population’s size distribution toward smaller individuals. These mechanisms produce sharp predictions about changes in seafood markets. Hypoxia is hypothesized to decrease the quantity of large shrimp relative to small shrimp and increase the price of large shrimp relative to small shrimp. We test these hypotheses using time series of size-based prices. Naive quantity-based models using treatment/control comparisons in hypoxic and nonhypoxic areas produce null results, but we find strong evidence of the hypothesized effects in the relative prices: Hypoxia increases the relative price of large shrimp compared with small shrimp. The effects of fuel prices provide supporting evidence. Empirical models of fishing effort and bioeconomic simulations explain why quantifying effects of hypoxia on fisheries using quantity data has been inconclusive. Specifically, spatial-dynamic feedbacks across the natural system (the fish stock) and human system (the mobile fishing fleet) confound “treated” and “control” areas. Consequently, analyses of price data, which rely on a market counterfactual, are able to reveal effects of the ecological disturbance that are obscured in quantity data. Our results are an important step toward quantifying the economic value of reduced upstream nutrient loading in the Mississippi Basin and are broadly applicable to other coupled human-natural systems. PMID:28137850
Seafood prices reveal impacts of a major ecological disturbance.
Smith, Martin D; Oglend, Atle; Kirkpatrick, A Justin; Asche, Frank; Bennear, Lori S; Craig, J Kevin; Nance, James M
2017-02-14
Coastal hypoxia (dissolved oxygen ≤ 2 mg/L) is a growing problem worldwide that threatens marine ecosystem services, but little is known about economic effects on fisheries. Here, we provide evidence that hypoxia causes economic impacts on a major fishery. Ecological studies of hypoxia and marine fauna suggest multiple mechanisms through which hypoxia can skew a population's size distribution toward smaller individuals. These mechanisms produce sharp predictions about changes in seafood markets. Hypoxia is hypothesized to decrease the quantity of large shrimp relative to small shrimp and increase the price of large shrimp relative to small shrimp. We test these hypotheses using time series of size-based prices. Naive quantity-based models using treatment/control comparisons in hypoxic and nonhypoxic areas produce null results, but we find strong evidence of the hypothesized effects in the relative prices: Hypoxia increases the relative price of large shrimp compared with small shrimp. The effects of fuel prices provide supporting evidence. Empirical models of fishing effort and bioeconomic simulations explain why quantifying effects of hypoxia on fisheries using quantity data has been inconclusive. Specifically, spatial-dynamic feedbacks across the natural system (the fish stock) and human system (the mobile fishing fleet) confound "treated" and "control" areas. Consequently, analyses of price data, which rely on a market counterfactual, are able to reveal effects of the ecological disturbance that are obscured in quantity data. Our results are an important step toward quantifying the economic value of reduced upstream nutrient loading in the Mississippi Basin and are broadly applicable to other coupled human-natural systems.
NASA Astrophysics Data System (ADS)
Roşu, M. M.; Tarbă, C. I.; Neagu, C.
2016-11-01
The current models for inventory management are complementary, but together they offer a large pallet of elements for solving complex problems of companies when wanting to establish the optimum economic order quantity for unfinished products, row of materials, goods etc. The main objective of this paper is to elaborate an automated decisional model for the calculus of the economic order quantity taking into account the price regressive rates for the total order quantity. This model has two main objectives: first, to determine the periodicity when to be done the order n or the quantity order q; second, to determine the levels of stock: lighting control, security stock etc. In this way we can provide the answer to two fundamental questions: How much must be ordered? When to Order? In the current practice, the business relationships with its suppliers are based on regressive rates for price. This means that suppliers may grant discounts, from a certain level of quantities ordered. Thus, the unit price of the products is a variable which depends on the order size. So, the most important element for choosing the optimum for the economic order quantity is the total cost for ordering and this cost depends on the following elements: the medium price per units, the stock cost, the ordering cost etc.
Towards large-scale plasma-assisted synthesis of nanowires
NASA Astrophysics Data System (ADS)
Cvelbar, U.
2011-05-01
Large quantities of nanomaterials, e.g. nanowires (NWs), are needed to overcome the high market price of nanomaterials and make nanotechnology widely available for general public use and applications to numerous devices. Therefore, there is an enormous need for new methods or routes for synthesis of those nanostructures. Here plasma technologies for synthesis of NWs, nanotubes, nanoparticles or other nanostructures might play a key role in the near future. This paper presents a three-dimensional problem of large-scale synthesis connected with the time, quantity and quality of nanostructures. Herein, four different plasma methods for NW synthesis are presented in contrast to other methods, e.g. thermal processes, chemical vapour deposition or wet chemical processes. The pros and cons are discussed in detail for the case of two metal oxides: iron oxide and zinc oxide NWs, which are important for many applications.
Zhu, Yuyang; Yan, Maomao; Lasanajak, Yi; Smith, David F; Song, Xuezheng
2018-07-15
Despite the important advances in chemical and chemoenzymatic synthesis of glycans, access to large quantities of complex natural glycans remains a major impediment to progress in Glycoscience. Here we report a large-scale preparation of N-glycans from a kilogram of commercial soy proteins using oxidative release of natural glycans (ORNG). The high mannose and paucimannose N-glycans were labeled with a fluorescent tag and purified by size exclusion and multidimensional preparative HPLC. Side products are identified and potential mechanisms for the oxidative release of natural N-glycans from glycoproteins are proposed. This study demonstrates the potential for using the ORNG approach as a complementary route to synthetic approaches for the preparation of multi-milligram quantities of biomedically relevant complex glycans. Copyright © 2018 Elsevier Ltd. All rights reserved.
USDA-ARS?s Scientific Manuscript database
An analytical and statistical method has been developed to measure the ultrasound-enhanced bioscouring performance of milligram quantities of endo- and exo-polygalacturonase enzymes obtained from Rhizopus oryzae fungi. UV-Vis spectrophotometric data and a general linear mixed models procedure indic...
Charoud-Got, Jean; Emma, Giovanni; Seghers, John; Tumba-Tshilumba, Marie-France; Santoro, Anna; Held, Andrea; Snell, James; Emteborg, Håkan
2017-12-01
A reference material of a PM 2.5 -like atmospheric dust material has been prepared using a newly developed method. It is intended to certify values for the mass fraction of SO 4 2- , NO 3 - , Cl - (anions) and Na + , K + , NH 4 + , Ca 2+ , Mg 2+ (cations) in this material. A successful route for the preparation of the candidate reference material is described alongside with two alternative approaches that were abandoned. First, a PM 10 -like suspension was allowed to stand for 72 h. Next, 90% of the volume was siphoned off. The suspension was spiked with appropriate levels of the desired ions just prior to drop-wise shock-freezing in liquid nitrogen. Finally, freeze drying of the resulting ice kernels took place. In using this approach, it was possible to produce about 500 g of PM 2.5 -like material with appropriate characteristics. Fine dust in 150-mg portions was filled into vials under an inert atmosphere. The final candidate material approaches the EN12341 standard of a PM 2.5 -material containing the ions mentioned in Directive 2008/50/EC of the European Union. The material should be analysed using the CEN/TR 16269:2011 method for anions and cations in PM 2.5 collected on filters. The method described here is a relatively rapid means to obtain large quantities of PM 2.5 . With access to smaller freeze dryers, still 5 to 10 g per freeze-drying cycle can be obtained. Access to such quantities of PM 2.5 -like material could potentially be used for different kinds of experiments when performing research in this field. Graphical abstract The novelty of the method lies in transformation of a suspension with fine particulate matter to a homogeneous and stable powder with characteristics similar to air-sampled PM 2,5 . The high material yield in a relatively short time is a distinct advantage in comparison with collection of air-sampled PM 2,5 .
Purification, characterization and crystallization of the human 80S ribosome
Khatter, Heena; Myasnikov, Alexander G.; Mastio, Leslie; Billas, Isabelle M. L.; Birck, Catherine; Stella, Stefano; Klaholz, Bruno P.
2014-01-01
Ribosomes are key macromolecular protein synthesis machineries in the cell. Human ribosomes have so far not been studied to atomic resolution because of their particularly complex structure as compared with other eukaryotic or prokaryotic ribosomes, and they are difficult to prepare to high homogeneity, which is a key requisite for high-resolution structural work. We established a purification protocol for human 80S ribosomes isolated from HeLa cells that allows obtaining large quantities of homogenous samples as characterized by biophysical methods using analytical ultracentrifugation and multiangle laser light scattering. Samples prepared under different conditions were characterized by direct single particle imaging using cryo electron microscopy, which helped optimizing the preparation protocol. From a small data set, a 3D reconstruction at subnanometric resolution was obtained showing all prominent structural features of the human ribosome, and revealing a salt concentration dependence of the presence of the exit site tRNA, which we show is critical for obtaining crystals. With these well-characterized samples first human 80S ribosome crystals were obtained from several crystallization conditions in capillaries and sitting drops, which diffract to 26 Å resolution at cryo temperatures and for which the crystallographic parameters were determined, paving the way for future high-resolution work. PMID:24452798
Temperature scaling method for Markov chains.
Crosby, Lonnie D; Windus, Theresa L
2009-01-22
The use of ab initio potentials in Monte Carlo simulations aimed at investigating the nucleation kinetics of water clusters is complicated by the computational expense of the potential energy determinations. Furthermore, the common desire to investigate the temperature dependence of kinetic properties leads to an urgent need to reduce the expense of performing simulations at many different temperatures. A method is detailed that allows a Markov chain (obtained via Monte Carlo) at one temperature to be scaled to other temperatures of interest without the need to perform additional large simulations. This Markov chain temperature-scaling (TeS) can be generally applied to simulations geared for numerous applications. This paper shows the quality of results which can be obtained by TeS and the possible quantities which may be extracted from scaled Markov chains. Results are obtained for a 1-D analytical potential for which the exact solutions are known. Also, this method is applied to water clusters consisting of between 2 and 5 monomers, using Dynamical Nucleation Theory to determine the evaporation rate constant for monomer loss. Although ab initio potentials are not utilized in this paper, the benefit of this method is made apparent by using the Dang-Chang polarizable classical potential for water to obtain statistical properties at various temperatures.
Techniques for determining physical zones of influence
Hamann, Hendrik F; Lopez-Marrero, Vanessa
2013-11-26
Techniques for analyzing flow of a quantity in a given domain are provided. In one aspect, a method for modeling regions in a domain affected by a flow of a quantity is provided which includes the following steps. A physical representation of the domain is provided. A grid that contains a plurality of grid-points in the domain is created. Sources are identified in the domain. Given a vector field that defines a direction of flow of the quantity within the domain, a boundary value problem is defined for each of one or more of the sources identified in the domain. Each of the boundary value problems is solved numerically to obtain a solution for the boundary value problems at each of the grid-points. The boundary problem solutions are post-processed to model the regions affected by the flow of the quantity on the physical representation of the domain.
Overcomplete compact representation of two-particle Green's functions
NASA Astrophysics Data System (ADS)
Shinaoka, Hiroshi; Otsuki, Junya; Haule, Kristjan; Wallerberger, Markus; Gull, Emanuel; Yoshimi, Kazuyoshi; Ohzeki, Masayuki
2018-05-01
Two-particle Green's functions and the vertex functions play a critical role in theoretical frameworks for describing strongly correlated electron systems. However, numerical calculations at the two-particle level often suffer from large computation time and massive memory consumption. We derive a general expansion formula for the two-particle Green's functions in terms of an overcomplete representation based on the recently proposed "intermediate representation" basis. The expansion formula is obtained by decomposing the spectral representation of the two-particle Green's function. We demonstrate that the expansion coefficients decay exponentially, while all high-frequency and long-tail structures in the Matsubara-frequency domain are retained. This representation therefore enables efficient treatment of two-particle quantities and opens a route to the application of modern many-body theories to realistic strongly correlated electron systems.
Monte Carlo calculation of the radiation field at aircraft altitudes.
Roesler, S; Heinrich, W; Schraube, H
2002-01-01
Energy spectra of secondary cosmic rays are calculated for aircraft altitudes and a discrete set of solar modulation parameters and rigidity cut-off values covering all possible conditions. The calculations are based on the Monte Carlo code FLUKA and on the most recent information on the interstellar cosmic ray flux including a detailed model of solar modulation. Results are compared to a large variety of experimental data obtained on the ground and aboard aircraft and balloons, such as neutron, proton, and muon spectra and yields of charged particles. Furthermore, particle fluence is converted into ambient dose equivalent and effective dose and the dependence of these quantities on height above sea level, solar modulation, and geographical location is studied. Finally, calculated dose equivalent is compared to results of comprehensive measurements performed aboard aircraft.
Effect of oil on an electrowetting lenticular lens and related optical characteristics.
Shin, Dooseub; Kim, Junoh; Kim, Cheoljoong; Koo, Gyo Hyun; Sim, Jee Hoon; Lee, Junsik; Won, Yong Hyub
2017-03-01
While there are many ways to realize autostereoscopic 2D/3D switchable displays, the electrowetting lenticular lens is superior due to the high optical efficiency and short response time. In this paper, we propose a more stable electrowetting lenticular lens by controlling the quantity of oil. With a large amount of oil, the oil layer was broken and the lenticular lens was damaged at relatively low voltage. Therefore, controlling the amount of oil is crucial to obtain the required dioptric power with stability. We proposed a new structure to evenly adjust the volume of oil and the dioptric power was measured by varying the volume of oil. Furthermore, the optical characteristics were finally analyzed in the electrowetting lenticular lens array with a proper amount of oil.
Electronic Structure Calculation of Permanent Magnets using the KKR Green's Function Method
NASA Astrophysics Data System (ADS)
Doi, Shotaro; Akai, Hisazumi
2014-03-01
Electronic structure and magnetic properties of permanent magnetic materials, especially Nd2Fe14B, are investigated theoretically using the KKR Green's function method. Important physical quantities in magnetism, such as magnetic moment, Curie temperature, and anisotropy constant, which are obtained from electronics structure calculations in both cases of atomic-sphere-approximation and full-potential treatment, are compared with past band structure calculations and experiments. The site preference of heavy rare-earth impurities are also evaluated through the calculation of formation energy with the use of coherent potential approximations. Further, the development of electronic structure calculation code using the screened KKR for large super-cells, which is aimed at studying the electronic structure of realistic microstructures (e.g. grain boundary phase), is introduced with some test calculations.
Process for the removal of radium from acidic solutions containing same
Scheitlin, F.M.
The invention is a process for the removal of radium from acidic aqueous solutions. In one aspect, the invention is a process for removing radium from an inorganic-acid solution. The process comprises contacting the solution with coal fly ash to effect adsorption of the radium on the ash. The radium-containing ash then is separated from the solution. The process is simple, comparatively inexpensive, and efficient. High radium-distribution coefficients are obtained even at room temperature. Coal fly ash is an inexpensive, acid-resistant, high-surface-area material which is available in large quantities throughout the United States. The invention is applicable, for example, to the recovery of /sup 226/Ra from nitric acid solutions which have been used to leach radium from uranium-mill tailings.
Separation of granulocytes from whole blood by leukoadhesion, phase 1
NASA Technical Reports Server (NTRS)
1976-01-01
Capillary glass tubes are investigated for the separation and retrieval of large quantities of viable granulocytes and monocytes from whole blood on a continuous basis from a single donor. This effort represented the feasibility demonstration of a three phase program for development of a capillary tube cell separation device. The activity included the analysis and parametric laboratory testing with subscale models required to design a prototype device. Capillary tubes 40 cm long with a nominal 0.030 cm internal diameter yielded the highest total process efficiency. Recovery efficiencies as high as 89% of the adhering cell population were obtained. Granulocyte phagocytosis of latex particles indicated approximately 90% viability. Monocytes recovered from the separation column retained their capability to stimulate human bone marrow colony growth, as demonstrated in an in vitro cell culture assay.
Removal of radium from acidic solutions containing same by adsorption on coal fly ash
Scheitlin, Frank M.
1984-01-01
The invention is a process for the removal of radium from acidic aqueous solutions. In one aspect, the invention is a process for removing radium from an inorganic-acid solution. The process comprises contacting the solution with coal fly ash to effect adsorption of the radium on the ash. The radium-containing ash then is separated from the solution. The process is simple, comparatively inexpensive, and efficient. High radium-distribution coefficients are obtained even at room temperature. Coal fly ash is an inexpensive, acid-resistant, high-surface-area material which is available in large quantities throughout the United States. The invention is applicable, for example, to the recovery of .sup.226 Ra from nitric acid solutions which have been used to leach radium from uranium-mill tailings.
Analysis and optimization of population annealing
NASA Astrophysics Data System (ADS)
Amey, Christopher; Machta, Jonathan
2018-03-01
Population annealing is an easily parallelizable sequential Monte Carlo algorithm that is well suited for simulating the equilibrium properties of systems with rough free-energy landscapes. In this work we seek to understand and improve the performance of population annealing. We derive several useful relations between quantities that describe the performance of population annealing and use these relations to suggest methods to optimize the algorithm. These optimization methods were tested by performing large-scale simulations of the three-dimensional (3D) Edwards-Anderson (Ising) spin glass and measuring several observables. The optimization methods were found to substantially decrease the amount of computational work necessary as compared to previously used, unoptimized versions of population annealing. We also obtain more accurate values of several important observables for the 3D Edwards-Anderson model.
Neutron production mechanism in a plasma focus.
NASA Technical Reports Server (NTRS)
Lee, J. H.; Shomo, L. P.; Williams, M. D.; Hermansdorfer, H.
1971-01-01
The neutrons emitted by a plasma focus were analyzed by using a time-of-flight method. Flight paths as large as 80 m were used to obtain better than 10% energy resolution. The energy spectrum of neutrons from d-d reactions in the plasma focus shows a sharp onset with average maximum energies of 2.8 and 3.2 MeV in the radial and the axial directions, respectively. The average half-width of the energy spectrum was 270 keV with a shot-to-shot variation between 150 and 400 keV. Simultaneous measurements in the axial and radial directions showed no appreciable difference in the half-widths and thus indicated randomly oriented ion velocities in the plasma. A converging ion model is described which is found to be in agreement with the measured quantities.
Ruhoff, J.R.; Winters, C.E.
1957-11-12
A process is described for the purification of uranyl nitrate by an extraction process. A solution is formed consisting of uranyl nitrate, together with the associated impurities arising from the HNO/sub 3/ leaching of the ore, in an organic solvent such as ether. If this were back extracted with water to remove the impurities, large quantities of uranyl nitrate will also be extracted and lost. To prevent this, the impure organic solution is extracted with small amounts of saturated aqueous solutions of uranyl nitrate thereby effectively accomplishing the removal of impurities while not allowing any further extraction of the uranyl nitrate from the organic solvent. After the impurities have been removed, the uranium values are extracted with large quantities of water.
Bär, David; Debus, Heiko; Grune, Christian; Tosch, Stephan; Fischer, Wolfgang; Mäder, Karsten; Imming, Peter
2017-12-01
Naproxen is a typical and well-known analgesic classified as non-steroidal anti-inflammatory drug (NSAID) and is commercialized as tablets or liquid-filled capsules. Naproxen is typically used asa sodium salt because of its better processability compared to Naproxen free acid. This entails hygroscopicity and gives rise to the existence of four different hydrates, which show polymorphic and pseudopolymorphic properties. Solid dosage forms containing Naproxen Sodium often have to be processed in an applicable dosage form by granulation and tablet compression. During granulation, Naproxen Sodium will be in contact with water and is exposed to the drop and rise in temperature and to mechanical stress. The result could be a mixture of different hydrates of Naproxen Sodium. This study showed that a modified designed fluid bed granulation was not affected by differences in the mixing ratio of hydrates when using different water contents after spraying and at the end with the finished granules. Here, X-ray diffraction combined with Rietveld refinement was used to analyze the ratio of the hydrates and its identity. All granulation batches showed a large amount of Naproxen Sodium Monohydrate (>87%) and no differences could be observed during tablet compression. Quantities of other hydrates were negligibly small. Furthermore, this study also demonstrated the influence of tablet compression by transforming the hydrates of the granules. In addition to Naproxen Sodium Monohydrate, a large quantity of amorphous structures has also been found. Rietveld evaluation combined with the preliminary studies of the raw hydrates provided conclusions on the drug release of the tablets containing hydrates of Naproxen Sodium which were influenced by tablet compression. Fast drug release was obtained when a maximum water content of about 21% was used after spraying during granulation, independently of the final water content of the finished granules. A maximum water content of less than 21% after spraying yielded a high quantity of amorphous components after tablet compression and thus worsened the drug release. Copyright © 2017 Elsevier B.V. All rights reserved.
Akmalov, Artem E; Chistyakov, Alexander A; Kotkovskii, Gennadii E
2017-08-01
Application of laser-induced desorption was investigated as a method of increasing the efficiency of gas phase analyzers on principles of field asymmetric ion mobility spectrometry. Mass spectrometric data of investigations of laser desorption of pentaerythritoltetranitrate molecules and cyclotetramethylenetetranitramine molecules from quartz substrate under vacuum were obtained. Laser sources a Nd 3+ :YAG with nanosecond pulse duration (λ = 532 nm) and a continuous wave diode laser (λ = 440 nm) were used. It was shown that both laser sources have different desorption abilities. This is expressed in various time of appearance of desorbed products that is caused by different heating mechanisms of surface layer. The desorbed quantity under action of both laser sources exceeds the detection threshold for all modern gas phase analyzers. It should be noted that despite the presence of surface dissociation of explosives under laser radiation, the quantity of nondissociated molecules is large enough for detection by ion mobility and field asymmetric ion mobility spectrometers. The optimal parameters of laser radiation for effective removal (evaporation) molecules of low-volatile compounds from surfaces are defined. The conclusion about preferable use of a Nd 3+ :YAG laser for increasing the detection ability of detectors based on ion mobility spectrometry was made.
Sensitivity Analysis of the Static Aeroelastic Response of a Wing
NASA Technical Reports Server (NTRS)
Eldred, Lloyd B.
1993-01-01
A technique to obtain the sensitivity of the static aeroelastic response of a three dimensional wing model is designed and implemented. The formulation is quite general and accepts any aerodynamic and structural analysis capability. A program to combine the discipline level, or local, sensitivities into global sensitivity derivatives is developed. A variety of representations of the wing pressure field are developed and tested to determine the most accurate and efficient scheme for representing the field outside of the aerodynamic code. Chebyshev polynomials are used to globally fit the pressure field. This approach had some difficulties in representing local variations in the field, so a variety of local interpolation polynomial pressure representations are also implemented. These panel based representations use a constant pressure value, a bilinearly interpolated value. or a biquadraticallv interpolated value. The interpolation polynomial approaches do an excellent job of reducing the numerical problems of the global approach for comparable computational effort. Regardless of the pressure representation used. sensitivity and response results with excellent accuracy have been produced for large integrated quantities such as wing tip deflection and trim angle of attack. The sensitivities of such things as individual generalized displacements have been found with fair accuracy. In general, accuracy is found to be proportional to the relative size of the derivatives to the quantity itself.
Solving lot-sizing problem with quantity discount and transportation cost
NASA Astrophysics Data System (ADS)
Lee, Amy H. I.; Kang, He-Yau; Lai, Chun-Mei
2013-04-01
Owing to today's increasingly competitive market and ever-changing manufacturing environment, the inventory problem is becoming more complicated to solve. The incorporation of heuristics methods has become a new trend to tackle the complex problem in the past decade. This article considers a lot-sizing problem, and the objective is to minimise total costs, where the costs include ordering, holding, purchase and transportation costs, under the requirement that no inventory shortage is allowed in the system. We first formulate the lot-sizing problem as a mixed integer programming (MIP) model. Next, an efficient genetic algorithm (GA) model is constructed for solving large-scale lot-sizing problems. An illustrative example with two cases in a touch panel manufacturer is used to illustrate the practicality of these models, and a sensitivity analysis is applied to understand the impact of the changes in parameters to the outcomes. The results demonstrate that both the MIP model and the GA model are effective and relatively accurate tools for determining the replenishment for touch panel manufacturing for multi-periods with quantity discount and batch transportation. The contributions of this article are to construct an MIP model to obtain an optimal solution when the problem is not too complicated itself and to present a GA model to find a near-optimal solution efficiently when the problem is complicated.
Worldwide photometry of the January 1989 Tau Persei eclipse
NASA Technical Reports Server (NTRS)
Hall, Douglas S.; Curott, David R.; Barksdale, William S.; Diethelm-Sutter, Roger; Ells, Jack
1991-01-01
New UBV photoelectric photometry of Tau Persei obtained at 19 different observatories during its recent January 1989 eclipse is presented. Mideclipse occurred at JD 2 447 542.31 + or - 0.01. The resulting light curve, though not complete at all phases, is solved for the elements with the help of two quantities derived from spectroscopy: the eclipse is 84 percent total at mideclipse, and the ratio of the radii is 0.135 + or - 0.01. Radii relative to the semimajor axis are 0.0236 for the G5 giant and 0.0032 for the A2 star. With a reasonable total mass assumed, the absolute radii say the A2 star could be luminosity class V or somewhat evolved and the G5 star is between III and II but could be closer to II. The G5 giant is brighter than the A2 star by 1.72 mag in V and the color excess in B - V is 0.06 mag, both quantities consistent (within uncertainties) with earlier estimates of Ake (1986). The eclipse duration, from first to fourth contact, is 2.09 day. The orbital inclination is 88.74 deg, consistent with what McAlister derived from speckle interferometry. Because of the large (e = 0.73) eccentricity, there is no secondary eclipse at all.
Ecophysiology of avian migration in the face of current global hazards
Klaassen, Marcel; Hoye, Bethany J.; Nolet, Bart A.; Buttemer, William A.
2012-01-01
Long-distance migratory birds are often considered extreme athletes, possessing a range of traits that approach the physiological limits of vertebrate design. In addition, their movements must be carefully timed to ensure that they obtain resources of sufficient quantity and quality to satisfy their high-energy needs. Migratory birds may therefore be particularly vulnerable to global change processes that are projected to alter the quality and quantity of resource availability. Because long-distance flight requires high and sustained aerobic capacity, even minor decreases in vitality can have large negative consequences for migrants. In the light of this, we assess how current global change processes may affect the ability of birds to meet the physiological demands of migration, and suggest areas where avian physiologists may help to identify potential hazards. Predicting the consequences of global change scenarios on migrant species requires (i) reconciliation of empirical and theoretical studies of avian flight physiology; (ii) an understanding of the effects of food quality, toxicants and disease on migrant performance; and (iii) mechanistic models that integrate abiotic and biotic factors to predict migratory behaviour. Critically, a multi-dimensional concept of vitality would greatly facilitate evaluation of the impact of various global change processes on the population dynamics of migratory birds. PMID:22566678
Big data in health care: using analytics to identify and manage high-risk and high-cost patients.
Bates, David W; Saria, Suchi; Ohno-Machado, Lucila; Shah, Anand; Escobar, Gabriel
2014-07-01
The US health care system is rapidly adopting electronic health records, which will dramatically increase the quantity of clinical data that are available electronically. Simultaneously, rapid progress has been made in clinical analytics--techniques for analyzing large quantities of data and gleaning new insights from that analysis--which is part of what is known as big data. As a result, there are unprecedented opportunities to use big data to reduce the costs of health care in the United States. We present six use cases--that is, key examples--where some of the clearest opportunities exist to reduce costs through the use of big data: high-cost patients, readmissions, triage, decompensation (when a patient's condition worsens), adverse events, and treatment optimization for diseases affecting multiple organ systems. We discuss the types of insights that are likely to emerge from clinical analytics, the types of data needed to obtain such insights, and the infrastructure--analytics, algorithms, registries, assessment scores, monitoring devices, and so forth--that organizations will need to perform the necessary analyses and to implement changes that will improve care while reducing costs. Our findings have policy implications for regulatory oversight, ways to address privacy concerns, and the support of research on analytics. Project HOPE—The People-to-People Health Foundation, Inc.
A high-yield procedure for isolation of metaphase chromosomes from root tips of Vicia faba L.
Doležel, J; Cíhalíková, J; Lucretti, S
1992-08-01
A new method is described for the isolation of large quantities of Vicia faba metaphase chromosomes. Roots were treated with 2.5 mM hydroxyurea for 18 h to accumulate meristem tip cells at the G1/S interface. After release from the block, the cells re-entered the cell cycle with a high degree of synchrony. A treatment with 2.5 μM amiprophos-methyl (APM) was used to accumulate mitotic cells in metaphase. The highest metaphase index (53.9%) was achieved when, 6 h after the release from the hydroxyurea block, the roots were exposed to APM for 4 h. The chromosomes were released from formaldehyde-fixed root tips by chopping with a scalpel in LB01 lysis buffer. Both the quality and the quantity of isolated chromosomes, examined microscopically and by flow cytometry, depended on the extent of the fixation. The best results were achieved after fixation with 6% formaldehyde for 30 min. Under these conditions, 1 · 10(6) chromosomes were routinely obtained from 30 root tips. The chromosomes were morphologically intact and suitable both for high-resolution chromosome studies and for flow-cytometric analysis and sorting. After the addition of hexylene glycol, the chromosome suspensions could be stored at 4° C for six months without any signs of deterioration.
Nonconservative and reverse spectral transfer in Hasegawa-Mima turbulence
DOE Office of Scientific and Technical Information (OSTI.GOV)
Terry, P.W.; Newman, D.E.
1993-01-01
The dual cascade is generally represented as a conservative cascade of enstrophy to short wavelengths through an enstrophy similarity range and an inverse cascade of energy to long wavelengths through an energy similarity range. This picture, based on a proof due to Kraichnan [Phys. Fluids 10, 1417 (1967)], is found to be significantly modified for a spectra of finite extent. Dimensional arguments and direct measurement of spectral flow in Hasegawa-Mima turbulence indicate that for both the energy and enstrophy cascades, transfer of the conserved quantity is accompanied by a nonconservative transfer of the other quantity. The decrease of a givenmore » invariant (energy or enstrophy) in the nonconservative transfer in one similarity range is balanced by the increase of that quantity in the other similarity range, thus maintaining net invariance. The increase or decrease of a given invariant quantity in one similarity range depends on the injection scale and is consistent with that quantity being carried in a self-similar transfer of the other invariant quantity. This leads, in an inertial range of finite size, to some energy being carried to small scales and some enstrophy being carried to large scales.« less
Nonconservative and reverse spectral transfer in Hasegawa--Mima turbulence
DOE Office of Scientific and Technical Information (OSTI.GOV)
Terry, P.W.; Newman, D.E.
1993-07-01
The dual cascade is generally represented as a conservative cascade of enstrophy to short wavelengths through an enstrophy similarity range and an inverse cascade of energy to long wavelengths through an energy similarity range. This picture, based on a proof due to Kraichnan [Phys. Fluids [bold 10], 1417 (1967)], is found to be significantly modified for spectra of finite extent. Dimensional arguments and direct measurement of spectral flow in Hasegawa--Mima turbulence indicate that for both the energy and enstrophy cascades, transfer of the conserved quantity is accompanied by a nonconservative transfer of the other quantity. The decrease of a givenmore » invariant (energy or enstrophy) in the nonconservative transfer in one similarity range is balanced by the increase of that quantity in the other similarity range, thus maintaining net invariance. The increase or decrease of a given invariant quantity in one similarity range depends on the injection scale and is consistent with that quantity being carried in a self-similar transfer of the other invariant quantity. This leads, in an inertial range of finite size, to some energy being carried to small scales and some enstrophy being carried to large scales.« less
Physical Uncertainty Bounds (PUB)
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vaughan, Diane Elizabeth; Preston, Dean L.
2015-03-19
This paper introduces and motivates the need for a new methodology for determining upper bounds on the uncertainties in simulations of engineered systems due to limited fidelity in the composite continuum-level physics models needed to simulate the systems. We show that traditional uncertainty quantification methods provide, at best, a lower bound on this uncertainty. We propose to obtain bounds on the simulation uncertainties by first determining bounds on the physical quantities or processes relevant to system performance. By bounding these physics processes, as opposed to carrying out statistical analyses of the parameter sets of specific physics models or simply switchingmore » out the available physics models, one can obtain upper bounds on the uncertainties in simulated quantities of interest.« less
NASA Astrophysics Data System (ADS)
Sue-Ann, Goh; Ponnambalam, S. G.
This paper focuses on the operational issues of a Two-echelon Single-Vendor-Multiple-Buyers Supply chain (TSVMBSC) under vendor managed inventory (VMI) mode of operation. To determine the optimal sales quantity for each buyer in TSVMBC, a mathematical model is formulated. Based on the optimal sales quantity can be obtained and the optimal sales price that will determine the optimal channel profit and contract price between the vendor and buyer. All this parameters depends upon the understanding of the revenue sharing between the vendor and buyers. A Particle Swarm Optimization (PSO) is proposed for this problem. Solutions obtained from PSO is compared with the best known results reported in literature.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Gates, A.A.; McCarthy, P.G.; Edl, J.W.
1975-05-01
Elemental tritium is shipped at low pressure in a stainless steel container (LP-50) surrounded by an aluminum vessel and Celotex insulation at least 4 in. thick in a steel drum. Each package contains a large quantity (greater than a Type A quantity) of nonfissile material, as defined in AECM 0529. This report provides the details of the safety analysis performed for this type container.
Code of Federal Regulations, 2011 CFR
2011-07-01
.... S = Concentration of SS from a user above a base level. Pc = O&M cost for treatment of a unit of any...(B)=Sc(S)=Pc(P)]Vu (3) Model No. 3. This model is commonly called the “quantity/quality formula”: Cu = Vc Vu=Bc Bu=Sc Su=Pc Pu (h) Other considerations. (1) Quantity discounts to large volume users will...
Forecasting Science and Technology for the Department of Defense
2009-12-01
Watson and Francis Crick announced that they had elucidated the structure of DNA and had therefore “discovered the secret of life.” While this was a...an organic chemist, figured out a process by which very small quantities of DNA could be amplified with high fidelity. This process, known as...polymerase chain reaction (PCR), for the first time, allowed scientists to produce DNA in large quantities. Roughly during this period, Leroy Hood and
Genistein Enhances or Reduces Glycosaminoglycan Quantity in a Cell Type-Specific Manner.
Lan, Ying; Li, Xiulian; Liu, Xuebo; Hao, Cui; Song, Ni; Ren, Sumei; Wang, Wei; Feng, Ningchuan; Zhang, Lijuan
2018-06-27
Genistein is a natural isoflavone enriched in soybeans. It has beneficial effects for patients with mucopolysaccharidose type III through inhibiting glycosaminoglycan biosynthesis. However, other studies indicate that genistein does not always inhibit glycosaminoglycan biosynthesis. To understand the underlying molecular mechanisms, CHOK1, CHO3.1, CHO3.3, and HCT116 cells were treated with genistein and the monosaccharide compositions and quantity of all glycans from the cell lysate were measured after thorough acid hydrolysis followed by HPLC analysis. In addition, the glycosaminoglycan disaccharide compositions were obtained by stable isotope labeling coupled with LC/MS analysis. Genistein treatment reduced the amount of glycans but increased the amount of glycosaminoglycans in HCT116 cells. In contrast, genistein treatment reduced both glycan and glycosaminoglycan quantities in CHOK1, CHO3.1, and CHO3.3 cells in addition to differential changes in glycosaminoglycan disaccharide compositions. Genistein treatment reduced overall glycan quantity but glycosaminoglycan quantities were either increased or decreased in a cell type-dependent manner. © 2018 The Author(s). Published by S. Karger AG, Basel.
NASA Technical Reports Server (NTRS)
Aboudi, Jacob; Pindera, Marek-Jerzy; Arnold, Steven M.
1993-01-01
A new micromechanical theory is presented for the response of heterogeneous metal matrix composites subjected to thermal gradients. In contrast to existing micromechanical theories that utilize classical homogenization schemes in the course of calculating microscopic and macroscopic field quantities, in the present approach the actual microstructural details are explicitly coupled with the macrostructure of the composite. Examples are offered that illustrate limitations of the classical homogenization approach in predicting the response of thin-walled metal matrix composites with large-diameter fibers when subjected to thermal gradients. These examples include composites with a finite number of fibers in the thickness direction that may be uniformly or nonuniformly spaced, thus admitting so-called functionally gradient composites. The results illustrate that the classical approach of decoupling micromechanical and macromechanical analyses in the presence of a finite number of large-diameter fibers, finite dimensions of the composite, and temperature gradient may produce excessively conservative estimates for macroscopic field quantities, while both underestimating and overestimating the local fluctuations of the microscopic quantities in different regions of the composite. Also demonstrated is the usefulness of the present approach in generating favorable stress distributions in the presence of thermal gradients by appropriately tailoring the internal microstructure details of the composite.
High-flexibility, noncollapsing lightweight hose
Williams, David A.
1993-01-01
A high-flexibility, noncollapsing, lightweight, large-bore, wire-reinforced hose is inside fiber-reinforced PVC tubing that is flexible, lightweight, and abrasion resistant. It provides a strong, kink- and collapse-free conduit for moving large quantities of dangerous fluids, e.g., removing radioactive waste water or processing chemicals.
High-flexibility, noncollapsing lightweight hose
Williams, D.A.
1993-04-20
A high-flexibility, noncollapsing, lightweight, large-bore, wire-reinforced hose is inside fiber-reinforced PVC tubing that is flexible, lightweight, and abrasion resistant. It provides a strong, kink- and collapse-free conduit for moving large quantities of dangerous fluids, e.g., removing radioactive waste water or processing chemicals.
NASA Technical Reports Server (NTRS)
Snyder, C. T.; Drinkwater, F. J., III; Fry, E. B.; Forrest, R. D.
1973-01-01
Data for use in development of takeoff airworthiness standards for new aircraft designs such as the supersonic transport (SST) and the large wide-body subsonic jet transport are provided. An advanced motion simulator was used to compare the performance and handling characteristics of three representative large jet transports during specific flight certification tasks. Existing regulatory constraints and methods for determining rotation speed were reviewed, and the effects on takeoff performance of variations in rotation speed, pitch attitude, and pitch attitude rate during the rotation maneuver were analyzed. A limited quantity of refused takeoff information was obtained. The aerodynamics, wing loading, and thrust-to-weight ratio of the subject SST resulted in takeoff speeds limited by climb (rather than lift-off) considerations. Take-off speeds based on U.S. subsonic transport requirements were found unacceptable because of the criticality of rotation-abuse effects on one-engine-inoperative climb performance. Adequate safety margin was provided by takeoff speeds based on proposed Anglo-French supersonic transport (TSS) criteria, with the limiting criterion being that takeoff safety speed be at least 1.15 times the one-engine-inoperative zero-rate-of-climb speed. Various observations related to SST certification are presented.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Suryanarayana, Phanish; Pratapa, Phanisri P.; Sharma, Abhiraj
We present SQDFT: a large-scale parallel implementation of the Spectral Quadrature (SQ) method formore » $$\\mathscr{O}(N)$$ Kohn–Sham Density Functional Theory (DFT) calculations at high temperature. Specifically, we develop an efficient and scalable finite-difference implementation of the infinite-cell Clenshaw–Curtis SQ approach, in which results for the infinite crystal are obtained by expressing quantities of interest as bilinear forms or sums of bilinear forms, that are then approximated by spatially localized Clenshaw–Curtis quadrature rules. We demonstrate the accuracy of SQDFT by showing systematic convergence of energies and atomic forces with respect to SQ parameters to reference diagonalization results, and convergence with discretization to established planewave results, for both metallic and insulating systems. Here, we further demonstrate that SQDFT achieves excellent strong and weak parallel scaling on computer systems consisting of tens of thousands of processors, with near perfect $$\\mathscr{O}(N)$$ scaling with system size and wall times as low as a few seconds per self-consistent field iteration. Finally, we verify the accuracy of SQDFT in large-scale quantum molecular dynamics simulations of aluminum at high temperature.« less
Large deviations of a long-time average in the Ehrenfest urn model
NASA Astrophysics Data System (ADS)
Meerson, Baruch; Zilber, Pini
2018-05-01
Since its inception in 1907, the Ehrenfest urn model (EUM) has served as a test bed of key concepts of statistical mechanics. Here we employ this model to study large deviations of a time-additive quantity. We consider two continuous-time versions of the EUM with K urns and N balls: with and without interactions between the balls in the same urn. We evaluate the probability distribution that the average number of balls in one urn over time T, , takes any specified value aN, where . For long observation time, , a Donsker–Varadhan large deviation principle holds: , where … denote additional parameters of the model. We calculate the rate function exactly by two different methods due to Donsker and Varadhan and compare the exact results with those obtained with a variant of WKB approximation (after Wentzel, Kramers and Brillouin). In the absence of interactions the WKB prediction for is exact for any N. In the presence of interactions the WKB method gives asymptotically exact results for . The WKB method also uncovers the (very simple) time history of the system which dominates the contribution of different time histories to .
Nakano, Yu; Iwanaga, Shinya; Mizumoto, Hiroshi; Kajiwara, Toshihisa
2018-03-03
Hematopoietic stem cells (HSCs) have the ability to differentiate into all types of blood cells and can be transplanted to treat blood disorders. However, it is difficult to obtain HSCs in large quantities because of the shortage of donors. Recent efforts have focused on acquiring HSCs by differentiation of pluripotent stem cells. As a conventional differentiation method of pluripotent stem cells, the formation of embryoid bodies (EBs) is often employed. However, the size of EBs is limited by depletion of oxygen and nutrients, which prevents them from being efficient for the production of HSCs. In this study, we developed a large-scale hematopoietic differentiation approach for mouse embryonic stem (ES) cells by applying a hollow fiber (HF)/organoid culture method. Cylindrical organoids, which had the potential for further spontaneous differentiation, were established inside of hollow fibers. Using this method, we improved the proliferation rate of mouse ES cells to produce an increased HSC population and achieved around a 40-fold higher production volume of HSCs in HF culture than in conventional EB culture. Therefore, the HF/organoid culture method may be a new mass culture method to acquire pluripotent stem cell-derived HSCs.
Suryanarayana, Phanish; Pratapa, Phanisri P.; Sharma, Abhiraj; ...
2017-12-07
We present SQDFT: a large-scale parallel implementation of the Spectral Quadrature (SQ) method formore » $$\\mathscr{O}(N)$$ Kohn–Sham Density Functional Theory (DFT) calculations at high temperature. Specifically, we develop an efficient and scalable finite-difference implementation of the infinite-cell Clenshaw–Curtis SQ approach, in which results for the infinite crystal are obtained by expressing quantities of interest as bilinear forms or sums of bilinear forms, that are then approximated by spatially localized Clenshaw–Curtis quadrature rules. We demonstrate the accuracy of SQDFT by showing systematic convergence of energies and atomic forces with respect to SQ parameters to reference diagonalization results, and convergence with discretization to established planewave results, for both metallic and insulating systems. Here, we further demonstrate that SQDFT achieves excellent strong and weak parallel scaling on computer systems consisting of tens of thousands of processors, with near perfect $$\\mathscr{O}(N)$$ scaling with system size and wall times as low as a few seconds per self-consistent field iteration. Finally, we verify the accuracy of SQDFT in large-scale quantum molecular dynamics simulations of aluminum at high temperature.« less
Estimation of gloss from rough surface parameters
NASA Astrophysics Data System (ADS)
Simonsen, Ingve; Larsen, Åge G.; Andreassen, Erik; Ommundsen, Espen; Nord-Varhaug, Katrin
2005-12-01
Gloss is a quantity used in the optical industry to quantify and categorize materials according to how well they scatter light specularly. With the aid of phase perturbation theory, we derive an approximate expression for this quantity for a one-dimensional randomly rough surface. It is demonstrated that gloss depends in an exponential way on two dimensionless quantities that are associated with the surface randomness: the root-mean-square roughness times the perpendicular momentum transfer for the specular direction, and a correlation function dependent factor times a lateral momentum variable associated with the collection angle. Rigorous Monte Carlo simulations are used to access the quality of this approximation, and good agreement is observed over large regions of parameter space.
Suh, D C; Manning, W G; Schondelmeyer, S; Hadsall, R S
2000-01-01
OBJECTIVE: To analyze the effect of multiple-source drug entry on price competition after patent expiration in the pharmaceutical industry. DATA SOURCES: Originators and their multiple-source drugs selected from the 35 chemical entities whose patents expired from 1984 through 1987. Data were obtained from various primary and secondary sources for the patents' expiration dates, sales volume and units sold, and characteristics of drugs in the sample markets. STUDY DESIGN: The study was designed to determine significant factors using the study model developed under the assumption that the off-patented market is an imperfectly segmented market. PRINCIPAL FINDINGS: After patent expiration, the originators' prices continued to increase, while the price of multiple-source drugs decreased significantly over time. By the fourth year after patent expiration, originators' sales had decreased 12 percent in dollars and 30 percent in quantity. Multiple-source drugs increased their sales twofold in dollars and threefold in quantity, and possessed about one-fourth (in dollars) and half (in quantity) of the total market three years after entry. CONCLUSION: After patent expiration, multiple-source drugs compete largely with other multiple-source drugs in the price-sensitive sector, but indirectly with the originator in the price-insensitive sector. Originators have first-mover advantages, and therefore have a market that is less price sensitive after multiple-source drugs enter. On the other hand, multiple-source drugs target the price-sensitive sector, using their lower-priced drugs. This trend may indicate that the off-patented market is imperfectly segmented between the price-sensitive and insensitive sector. Consumers as a whole can gain from the entry of multiple-source drugs because the average price of the market continually declines after patent expiration. PMID:10857475
Lin, Xiao-Li; Pan, Qin-Jian; Tian, Hong-Gang; Douglas, Angela E; Liu, Tong-Xian
2015-03-01
Microbial abundance and diversity of different life stages (fourth instar larvae, pupae and adults) of the diamondback moth, Plutella xylostella L., collected from field and reared in laboratory, were investigated using bacteria culture-dependent method and PCR-DGGE analysis based on the sequence of bacteria 16S rRNA V3 region gene. A large quantity of bacteria was found in all life stages of P. xylostella. Field population had higher quantity of bacteria than laboratory population, and larval gut had higher quantity than pupae and adults. Culturable bacteria differed in different life stages of P. xylostella. Twenty-five different bacterial strains were identified in total, among them 20 strains were presented in larval gut, only 8 strains in pupae and 14 strains in adults were detected. Firmicutes bacteria, Bacillus sp., were the most dominant species in every life stage. 15 distinct bands were obtained from DGGE electrophoresis gel. The sequences blasted in GenBank database showed these bacteria belonged to six different genera. Phylogenetic analysis showed the sequences of the bacteria belonged to the Actinobacteri, Proteobacteria and Firmicutes. Serratia sp. in Proteobacteria was the most abundant species in larval gut. In pupae, unculturable bacteria were the most dominant species, and unculturable bacteria and Serratia sp. were the most dominant species in adults. Our study suggested that a combination of molecular and traditional culturing methods can be effectively used to analyze and to determine the diversity of gut microflora. These known bacteria may play important roles in development of P. xylostella. © 2013 Institute of Zoology, Chinese Academy of Sciences.
Large-Scale Survey of the Structure of the Dayside Magnetopause by MMS
NASA Astrophysics Data System (ADS)
Paschmann, G.; Haaland, S. E.; Phan, T. D.; Sonnerup, B. U. Ö.; Burch, J. L.; Torbert, R. B.; Gershman, D. J.; Dorelli, J. C.; Giles, B. L.; Pollock, C.; Saito, Y.; Lavraud, B.; Russell, C. T.; Strangeway, R. J.; Baumjohann, W.; Fuselier, S. A.
2018-03-01
This paper describes the generation and initial utilization of a database containing 80 vector and scalar quantities, for a total of 8,670 magnetopause and magnetosheath current sheet crossings by MMS1, using plasma and magnetic field data from the Fast Plasma Investigation, Fluxgate Magnetometer, and Hot Plasma Composition Analyzer instruments, augmented by solar wind and interplanetary magnetic field data from CDAWeb. Based on a determination of the current sheet width, measured and calculated vector and scalar quantities are stored for the two sides of the current sheet and for selected times within the current sheet. The only manual operations were the classification of the current sheets according to the type of boundary, the character of the magnetic field transition, and the quality of the current sheet fit. To characterize the database, histograms of selected key quantities are presented. We then give the statistics for the duration, motion, and thicknesses of the magnetopause current sheet, using single-spacecraft techniques for the determination of the normal velocities, obtaining median results of 12.9 s, 38.5 km/s, and 705.4 km, respectively. When scaled to the ion inertial length, the median thickness became 12.6; there were no thicknesses less than one. Next, we apply the Walén relation to find crossings that are rotational discontinuities and thus may indicate ongoing magnetic reconnection. For crossings where the velocities in the outflow region exceed the velocity on the magnetosheath side by at least 250 km/s, 47% meet our rotational discontinuity criteria. If we require the outflow to exceed 250 km/s along the L direction, then the percentage rises to 68%.
The Event Horizon Telescope: Future Polarimetric Capabilities
NASA Astrophysics Data System (ADS)
Fish, Vincent L.; Doeleman, S. S.; EHT Collaboration
2010-01-01
The Event Horizon Telescope (EHT) is a (sub)mm wavelength VLBI network that will achieve angular resolutions sufficient to resolve and image the Event Horizons of the nearest supermassive black holes. Recent millimeter observations with the initial three stations of the EHT (located in Hawaii, Arizona, and California) have constrained the size of the emitting region of Sgr A*, the Galactic Center radio/infrared/X-ray source associated with a supermassive black hole, to be no more than a few Schwarzschild radii. While EHT observations have heretofore focused on detecting Sgr A* in total intensity, theoretical models predict large polarization signatures well in excess of the few percent linear polarization detected by low resolution arrays (e.g., SMA). Here, we generalize our previous total intensity simulations of future EHT observations to include full polarimetric quantities. Ratios of polarimetric visibilities provide baseline-based observables that are robust against most calibration errors. We find that the shortest VLBI baselines track the integrated polarization fraction and position angle, as presently observed by connected-element arrays, while longer VLBI baselines are sensitive to highly-polarized substructures that are beam-diluted at lower angular resolution. Ratios of polarized visibilities may be even more sensitive to detecting periodic structural changes, as might be expected from a hot spot near the innermost stable circular orbit of the black hole, than closure quantities obtained from total intensity quantities. These results suggest that high priority should be given to upgrading telescopes in the EHT collaboration in order to allow full polarimetric observations of Sgr A* and other supermassive black hole sources. This research is made possible thanks to funding provided by the National Science Foundation.
Ground water in Utah - A summary description of the resource and its related physical environment
Price, Don; Arnow, Ted
1985-01-01
Ground water is one of Utah’s most extensive and valuable natural resources. Because of its widespread occurrence in both wet and dry areas, ground water has been, and is a major factor affecting economic growth and development of the State. In some areas, ground water is used to supplement streamflow for irrigation, public supply, and other uses. In other areas, it is the only water available for use. Many communities obtain their entire water supply from ground-water sources (wells and springs) as do numerous rural and suburban households throughout the State.The ground-water reservoirs of Utah contain tremendous quantities of water – many times more than the quantity stored in all the lakes (including Great Salt Lake) and the surface-water reservoirs of the State combined. Water that discharges from those underground reservoirs in seeps and springs is vital in sustaining the flow of streams during dry summer months and in providing the water needed to maintain important wetland habitats. Those same underground reservoirs also provide large quantities of water in carryover storage for use during prolonged droughts.The U.S. Geological survey, under cooperative programs with the Utah department of Natural resources and other Federal, State, and local agencies has been studying Utah’s ground-water resources since 1897. Much information has been gained during those studies about the occurrence, availability, and quality of ground water; the withdrawal and use of the water; and the effects of withdrawal. This report summarizes that information in nontechnical language, which is designed for all readers. Readers interested in more detailed information about ground water in specific areas of Utah are referred to the reports listed by LaPray and Hamblin (1980).
Zhan, Liang-Tong; Xu, Hui; Chen, Yun-Min; Lan, Ji-Wu; Lin, Wei-An; Xu, Xiao-Bing; He, Pin-Jing
2017-10-01
The high food waste content (HFWC) MSW at a landfill has the characteristics of rapid hydrolysis process, large leachate production rate and fast gas generation. The liquid-gas interactions at HFWC-MSW landfills are prominent and complex, and still remain significant challenges. This paper focuses on the liquid-gas interactions of HFWC-MSW observed from a large-scale bioreactor landfill experiment (5m×5m×7.5m). Based on the connected and quantitative analyses on the experimental observations, the following findings were obtained: (1) The high leachate level observed at Chinese landfills was attributed to the combined contribution from the great quantity of self-released leachate, waste compression and gas entrapped underwater. The contribution from gas entrapped underwater was estimated to be 21-28% of the total leachate level. (2) The gas entrapped underwater resulted in a reduction of hydraulic conductivity, decreasing by one order with an increase in gas content from 13% to 21%. (3) The "breakthrough value" in the gas accumulation zone was up to 11kPa greater than the pore liquid pressure. The increase of the breakthrough value was associated with the decrease of void porosity induced by surcharge loading. (4) The self-released leachate from HFWC-MSW was estimated to contribute to over 30% of the leachate production at landfills in Southern China. The drainage of leachate with a high organic loading in the rapid hydrolysis stage would lead to a loss of landfill gas (LFG) potential of 13%. Based on the above findings, an improved method considering the quantity of self-released leachate was proposed for the prediction of leachate production at HFWC-MSW landfills. In addition, a three-dimensional drainage system was proposed to drawdown the high leachate level and hence to improve the slope stability of a landfill, reduce the hydraulic head on a bottom liner and increase the collection efficiency for LFG. Copyright © 2017. Published by Elsevier Ltd.
Quintana, Gabriel; Gerbino, Esteban; Gómez-Zavaglia, Andrea
2017-01-01
Okara is a nutritionally valuable by-product produced in large quantities as result of soymilk elaboration. This work proposes its use as both culture and dehydration medium during freeze-drying, spray-drying, and storage of Lactobacillus plantarum CIDCA 83114. Whole and defatted okara were employed as culture media for L. plantarum CIDCA 83114. The growth kinetics were followed by plate counting and compared with those of bacteria grown in MRS broth (control). No significant differences in plate counting were observed in the three media. The fatty acid composition of bacteria grown in whole and defatted okara showed a noticeable increase in the unsaturated/saturated (U/S) fatty acid ratio, with regard to bacteria grown in MRS. This change was mainly due to the increase in polyunsaturated fatty acids, namely C18:2. For dehydration assays, cultures in the stationary phase were neutralized and freeze-dried (with or without the addition of 250 mM sucrose) or spray-dried. Bacteria were plate counted immediately after freeze-drying or spray-drying and during storage at 4°C for 90 days. Freeze-drying in whole okara conducted to the highest bacterial recovery. Regarding storage, spray-dried bacteria previously grown in whole and defatted okara showed higher plate counts than those grown in MRS. On the contrary, freeze-dried bacteria previously grown in all the three culture media were those with the lowest plate counts. The addition of sucrose to the dehydration media improved their recovery. The higher recovery of microorganisms grown in okara after freeze-drying and spray-drying processes and during storage was ascribed to both the presence of fiber and proteins in the dehydration media, and the increase in U/S fatty acids ratio in bacterial membranes. The obtained results support for the first time the use of okara as an innovative matrix to deliver L. plantarum . Considering that okara is an agro-waste obtained in large quantities, these results represent an innovative strategy to add it value, providing a symbiotic ingredient with promising industrial applications in the development of novel functional foods and feeds.
Quintana, Gabriel; Gerbino, Esteban; Gómez-Zavaglia, Andrea
2017-01-01
Okara is a nutritionally valuable by-product produced in large quantities as result of soymilk elaboration. This work proposes its use as both culture and dehydration medium during freeze-drying, spray-drying, and storage of Lactobacillus plantarum CIDCA 83114. Whole and defatted okara were employed as culture media for L. plantarum CIDCA 83114. The growth kinetics were followed by plate counting and compared with those of bacteria grown in MRS broth (control). No significant differences in plate counting were observed in the three media. The fatty acid composition of bacteria grown in whole and defatted okara showed a noticeable increase in the unsaturated/saturated (U/S) fatty acid ratio, with regard to bacteria grown in MRS. This change was mainly due to the increase in polyunsaturated fatty acids, namely C18:2. For dehydration assays, cultures in the stationary phase were neutralized and freeze-dried (with or without the addition of 250 mM sucrose) or spray-dried. Bacteria were plate counted immediately after freeze-drying or spray-drying and during storage at 4°C for 90 days. Freeze-drying in whole okara conducted to the highest bacterial recovery. Regarding storage, spray-dried bacteria previously grown in whole and defatted okara showed higher plate counts than those grown in MRS. On the contrary, freeze-dried bacteria previously grown in all the three culture media were those with the lowest plate counts. The addition of sucrose to the dehydration media improved their recovery. The higher recovery of microorganisms grown in okara after freeze-drying and spray-drying processes and during storage was ascribed to both the presence of fiber and proteins in the dehydration media, and the increase in U/S fatty acids ratio in bacterial membranes. The obtained results support for the first time the use of okara as an innovative matrix to deliver L. plantarum. Considering that okara is an agro-waste obtained in large quantities, these results represent an innovative strategy to add it value, providing a symbiotic ingredient with promising industrial applications in the development of novel functional foods and feeds. PMID:28446905
17. CUPOLA TENDERS FILLED THE LARGE LADLES WORKERS USED TO ...
17. CUPOLA TENDERS FILLED THE LARGE LADLES WORKERS USED TO POUR MOLDS ON THE CONVEYORS FROM BULL LADLES THAT WERE USED TO STORE BATCH QUANTITIES OF IRON TAPPED FROM THE CUPOLA, CA. 1950. - Stockham Pipe & Fittings Company, 4000 Tenth Avenue North, Birmingham, Jefferson County, AL
Aćimović, Jugoslava; Mäki-Marttunen, Tuomo; Linne, Marja-Leena
2015-01-01
We developed a two-level statistical model that addresses the question of how properties of neurite morphology shape the large-scale network connectivity. We adopted a low-dimensional statistical description of neurites. From the neurite model description we derived the expected number of synapses, node degree, and the effective radius, the maximal distance between two neurons expected to form at least one synapse. We related these quantities to the network connectivity described using standard measures from graph theory, such as motif counts, clustering coefficient, minimal path length, and small-world coefficient. These measures are used in a neuroscience context to study phenomena from synaptic connectivity in the small neuronal networks to large scale functional connectivity in the cortex. For these measures we provide analytical solutions that clearly relate different model properties. Neurites that sparsely cover space lead to a small effective radius. If the effective radius is small compared to the overall neuron size the obtained networks share similarities with the uniform random networks as each neuron connects to a small number of distant neurons. Large neurites with densely packed branches lead to a large effective radius. If this effective radius is large compared to the neuron size, the obtained networks have many local connections. In between these extremes, the networks maximize the variability of connection repertoires. The presented approach connects the properties of neuron morphology with large scale network properties without requiring heavy simulations with many model parameters. The two-steps procedure provides an easier interpretation of the role of each modeled parameter. The model is flexible and each of its components can be further expanded. We identified a range of model parameters that maximizes variability in network connectivity, the property that might affect network capacity to exhibit different dynamical regimes.
NASA Technical Reports Server (NTRS)
Mahtani, H. K.; Richmond, R. C.; Chang, T. Y.; Chang, C. C. Y.; Rose, M. Franklin (Technical Monitor)
2001-01-01
The enzyme acyl-coenzyme A:cholesterol acyltransferase (ACAT) is an important contributor to the pathological expression of plaque leading to artherosclerosis n a major health problem. Adequate knowledge of the structure of this protein will enable pharmaceutical companies to design drugs specific to the enzyme. ACAT is a membrane protein located in the endoplasmic reticulum.t The protein has never been purified to homogeneity.T.Y. Chang's laboratory at Dartmouth College provided a 4-kb cDNA clone (K1) coding for a structural gene of the protein. We have modified the gene sequence and inserted the cDNA into the BioGreen His Baculovirus transfer vector. This was successfully expressed in Sf2l insect cells as a GFP-labeled ACAT protein. The advantage to this ACAT-GFP fusion protein (abbreviated GCAT) is that one can easily monitor its expression as a function of GFP excitation at 395 nm and emission at 509 nm. Moreover, the fusion protein GCAT can be detected on Western blots with the use of commercially available GFP antibodies. Antibodies against ACAT are not readily available. The presence of the 6xHis tag in the transfer vector facilitates purification of the recombinant protein since 6xHis fusion proteins bind with high affinity to Ni-NTA agarose. Obtaining highly pure protein in large quantities is essential for subsequent crystallization. The purified GCAT fusion protein can readily be cleaved into distinct GFP and ACAT proteins in the presence of thrombin. Thrombin digests the 6xHis tag linking the two protein sequences. Preliminary experiments have indicated that both GCAT and ACAT are expressed as functional proteins. The ultimate aim is to obtain large quantities of the ACAT protein in pure and functional form appropriate for protein crystal growth. Determining protein structure is the key to the design and development of effective drugs. X-ray analysis requires large homogeneous crystals that are difficult to obtain in the gravity environment of earth. Protein crystals grown in microgravity are often larger and have fewer defects than those grown on earth. The analysis of higher quality space-grown crystals will assist in structure-based drug design. We have successfully grown GCAT-infected Sf21 cells in both adhesion and suspension cultures. Expression levels of GCAT in cell lines such as Sf9 and High Five appear to be reduced. We intend to replicate GCAT expression in all three cell lines using the NASA rotating wall bioreactor which effectively duplicates a microgravity environment. The bioreactor itself could be launched to study the expression of the GFP and GCAT proteins in the actual microgravity environment achieved in orbit.
Uher, Jana; Call, Josep
2008-05-01
We tested 6 chimpanzees (Pan troglodytes), 3 orangutans (Pongo pygmaeus), 4 bonobos (Pan paniscus), and 2 gorillas (Gorilla gorilla) in the reversed reward contingency task. Individuals were presented with pairs of quantities ranging between 0 and 6 food items. Prior to testing, some experienced apes had solved this task using 2 quantities while others were totally naïve. Experienced apes transferred their ability to multiple-novel pairs after 6 to 19 months had elapsed since their initial testing. Two out of 6 naïve apes (1 chimpanzee, 1 bonobo) solved the task--a proportion comparable to that of a previous study using 2 pairs of quantities. Their acquisition speed was also comparable to the successful subjects from that study. The ratio between quantities explained a large portion of the variance but affected naïve and experienced individuals differently. For smaller ratios, naïve individuals were well below 50% correct and experienced ones were well above 50%, yet both groups tended to converge toward 50% for larger ratios. Thus, some apes require no procedural modifications to overcome their strong bias for selecting the larger of 2 quantities. PsycINFO Database Record (c) 2008 APA, all rights reserved.
Theobald, P.K.; Lakin, H.W.; Hawkins, D.B.
1963-01-01
The oxidation of disseminated pyrite in relatively acid schists and gneisses of the Snake River drainage basin provides abundant iron sulfate and sulfuric acid to ground and surface water. This acid water dissolves large quantities of many elements, particularly aluminum and surprisingly large quantities of elements, such as magnesium and zinc, not expected to be abundant in the drainage basin. The adjoining drainage to the west, Deer Creek, is underlain by basic rocks, from which the water inherits a high pH. Despite the presence of base- and precious- metal veins in the drainage basin of Deer Creek, it carries less metal than the Snake River. The principal precipitate on the bed of the Snake River is hydrated iron oxide with small quantities of the other metals. In Deer Creek manganese oxide is precipitated with iron oxide and large quantities of other metals are carried down with this precipitate. Below the junction of these streams the pH stabilizes at a near-neutral value. Iron is removed from the Snake River water at the junction, and aluminum is precipitated for some distance downstream. The aluminum precipitate carries down other metals in concentrations slightly less than that in the manganese precipitate on Deer Creek. The natural processes observed in this junction if carried to a larger scale could provide the mechanism described by Ansheles (1927) for the formation of bauxite. In the environment described, geochemical exploration by either water or stream sediment techniques is difficult because of (1) the extreme pH differential between the streams above their junction and (2) the difference in the precipitates formed on the streambeds. ?? 1963.
Converting solid wastes into liquid fuel using a novel methanolysis process.
Xiao, Ye; He, Peng; Cheng, Wei; Liu, Jacqueline; Shan, Wenpo; Song, Hua
2016-03-01
Biomass fast pyrolysis followed by hydrodeoxygenation upgrading is the most popular way to produce upgraded bio-oil from biomass. This process requires large quantities of expensive hydrogen and operates under high pressure condition (70-140 atm). Therefore, a novel methanolysis (i.e., biomass pyrolysis under methane environment) process is developed in this study, which is effective in upgraded bio-oil formation at atmospheric pressure and at about 400-600°C. Instead of using pure methane, simulated biogas (60% CH4+40% CO2) was used to test the feasibility of this novel methanolysis process for the conversion of different solid wastes. The bio-oil obtained from canola straw is slightly less than that from sawdust in term of quantity, but the oil quality from canola straw is better in terms of lower acidity, lower Bromine Number, higher H/C atomic ratio and lower O/C atomic ratio. The municipal solid waste and newspaper can also obtain relatively high oil yields, but the oil qualities of them are both lower than those from sawdust and canola straw. Compared with catalysts of 5%Zn/ZSM-5 and 1%Ag/ZSM-5, the 5%Zn-1%Ag/ZSM-5 catalyst performed much better in terms of upgraded bio-oil yield as well as oil quality. During the methanolysis process, the metal silver may be used to reduce the total acid number of the oil while the metal zinc might act to decrease the bromine number of the oil. The highly dispersed Zn and Ag species on/in the catalyst benefit the achievement of better upgrading performance and make it be a very promising catalyst for bio-oil upgrading by biogas. Copyright © 2015 Elsevier Ltd. All rights reserved.
A parametric method for determining the number of signals in narrow-band direction finding
NASA Astrophysics Data System (ADS)
Wu, Qiang; Fuhrmann, Daniel R.
1991-08-01
A novel and more accurate method to determine the number of signals in the multisource direction finding problem is developed. The information-theoretic criteria of Yin and Krishnaiah (1988) are applied to a set of quantities which are evaluated from the log-likelihood function. Based on proven asymptotic properties of the maximum likelihood estimation, these quantities have the properties required by the criteria. Since the information-theoretic criteria use these quantities instead of the eigenvalues of the estimated correlation matrix, this approach possesses the advantage of not requiring a subjective threshold, and also provides higher performance than when eigenvalues are used. Simulation results are presented and compared to those obtained from the nonparametric method given by Wax and Kailath (1985).
Monte Carlo calculation of proton stopping power and ranges in water for therapeutic energies
NASA Astrophysics Data System (ADS)
Bozkurt, Ahmet
2017-09-01
Monte Carlo is a statistical technique for obtaining numerical solutions to physical or mathematical problems that are analytically impractical, if not impossible, to solve. For charged particle transport problems, it presents many advantages over deterministic methods since such problems require a realistic description of the problem geometry, as well as detailed tracking of every source particle. Thus, MC can be considered as a powerful alternative to the well-known Bethe-Bloche equation where an equation with various corrections is used to obtain stopping power and ranges of electrons, positrons, protons, alphas, etc. This study presents how a stochastic method such as MC can be utilized to obtain certain quantities of practical importance related to charged particle transport. Sample simulation geometries were formed for water medium where disk shaped thin detectors were employed to compute average values of absorbed dose and flux at specific distances. For each detector cell, these quantities were utilized to evaluate the values of the range and the stopping power, as well as the shape of Bragg curve, for mono-energetic point source pencil beams of protons. The results were found to be ±2% compared to the data from the NIST compilation. It is safe to conclude that this approach can be extended to determine dosimetric quantities for other media, energies and charged particle types.
Fe(0) Nanomotors in Ton Quantities (10(20) Units) for Environmental Remediation.
Teo, Wei Zhe; Zboril, Radek; Medrik, Ivo; Pumera, Martin
2016-03-24
Despite demonstrating potential for environmental remediation and biomedical applications, the practical environmental applications of autonomous self-propelled micro-/nanorobots have been limited by the inability to fabricate these devices in large (kilograms/tons) quantities. In view of the demand for large-scale environmental remediation by micro-/nanomotors, which are easily synthesized and powered by nontoxic fuel, we have developed bubble-propelled Fe(0) Janus nanomotors by a facile thermally induced solid-state procedure and investigated their potential as decontamination agents of pollutants. These Fe(0) Janus nanomotors, stabilized by an ultrathin iron oxide shell, were fuelled by their decomposition in citric acid, leading to the asymmetric bubble propulsion. The degradation of azo-dyes was dramatically increased in the presence of moving self-propelled Fe(0) nanomotors, which acted as reducing agents. Such enhanced pollutant decomposition triggered by biocompatible Fe(0) (nanoscale zero-valent iron motors), which can be handled in the air and fabricated in ton quantities for low cost, will revolutionize the way that environmental remediation is carried out. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Developing a national stream morphology data exchange: needs, challenges, and opportunities
Collins, Mathias J.; Gray, John R.; Peppler, Marie C.; Fitzpatrick, Faith A.; Schubauer-Berigan, Joseph P.
2012-01-01
Stream morphology data, primarily consisting of channel and foodplain geometry and bed material size measurements, historically have had a wide range of applications and uses including culvert/ bridge design, rainfall- runoff modeling, food inundation mapping (e.g., U.S. Federal Emergency Management Agency food insurance studies), climate change studies, channel stability/sediment source investigations, navigation studies, habitat assessments, and landscape change research. The need for stream morphology data in the United States, and thus the quantity of data collected, has grown substantially over the past 2 decades because of the expanded interests of resource management agencies in watershed management and restoration. The quantity of stream morphology data collected has also increased because of state-of-the-art technologies capable of rapidly collecting high-resolution data over large areas with heretofore unprecedented precision. Despite increasing needs for and the expanding quantity of stream morphology data, neither common reporting standards nor a central data archive exist for storing and serving these often large and spatially complex data sets. We are proposing an open- access data exchange for archiving and disseminating stream morphology data.
Developing a national stream morphology data exchange: Needs, challenges, and opportunities
NASA Astrophysics Data System (ADS)
Collins, Mathias J.; Gray, John R.; Peppler, Marie C.; Fitzpatrick, Faith A.; Schubauer-Berigan, Joseph P.
2012-05-01
Stream morphology data, primarily consisting of channel and foodplain geometry and bed material size measurements, historically have had a wide range of applications and uses including culvert/ bridge design, rainfall- runoff modeling, food inundation mapping (e.g., U.S. Federal Emergency Management Agency food insurance studies), climate change studies, channel stability/sediment source investigations, navigation studies, habitat assessments, and landscape change research. The need for stream morphology data in the United States, and thus the quantity of data collected, has grown substantially over the past 2 decades because of the expanded interests of resource management agencies in watershed management and restoration. The quantity of stream morphology data collected has also increased because of state-of-the-art technologies capable of rapidly collecting high-resolution data over large areas with heretofore unprecedented precision. Despite increasing needs for and the expanding quantity of stream morphology data, neither common reporting standards nor a central data archive exist for storing and serving these often large and spatially complex data sets. We are proposing an open- access data exchange for archiving and disseminating stream morphology data.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Karch, Andreas; Robinson, Brandon
Thermodynamic quantities associated with black holes in Anti-de Sitter space obey an interesting identity when the cosmological constant is included as one of the dynamical variables, the generalized Smarr relation. Here, we show that this relation can easily be understood from the point of view of the dual holographic field theory. It amounts to the simple statement that the extensive thermodynamic quantities of a large N gauge theory only depend on the number of colors, N, via an overall factor of N 2.
Collective synthesis of natural products by means of organocascade catalysis
Jones, Spencer B.; Simmons, Bryon; Mastracchio, Anthony; MacMillan, David W. C.
2012-01-01
Organic chemists are now able to synthesize small quantities of almost any known natural product, given sufficient time, resources and effort. However, translation of the academic successes in total synthesis to the large-scale construction of complex natural products and the development of large collections of biologically relevant molecules present significant challenges to synthetic chemists. Here we show that the application of two nature-inspired techniques, namely organocascade catalysis and collective natural product synthesis, can facilitate the preparation of useful quantities of a range of structurally diverse natural products from a common molecular scaffold. The power of this concept has been demonstrated through the expedient, asymmetric total syntheses of six well-known alkaloid natural products: strychnine, aspidospermidine, vincadifformine, akuammicine, kopsanone and kopsinine. PMID:21753848
Zlatić, Nenad M; Stanković, Milan S; Simić, Zoran S
2017-03-01
The purpose of this comparative analysis is the determination of the total quantity of metals (Mg, Ca, K, Ni, Fe, Mn, Zn, Cu, Cr and Pb) in soil samples, above ground plant parts and tea made of plants Teucrium montanum and T. chamaedrys from different serpentine and calcareous habitats as well as of the total quantity of phenolic compounds and antioxidant activity. The obtained results showed that the quantities of certain metals (Mg, Fe, Ni and Mn) in the soil from the serpentine habitats were greater in comparison with other metals (Ca, Zn and Pb) which were more frequently found in the soil from the calcareous habitats. The results demonstrated that the analysed plant samples from the serpentine habitats contained higher quantity of Fe, Ni and Cr as opposed to the plant samples from the calcareous habitats which contained greater quantity of Ca and Zn. Although the studied species accumulate analysed metals in different quantities, depending on the substrate type, they are not hyperaccumulators of these metals. The use of these species from serpentine habitats for tea preparation is safe to a great extent, because in spite of the determined metal absorption by plant organs, the tea does not contain dangerous quantity of heavy metals. The results showed greater total quantity of phenolic compounds and the higher level of antioxidant activity in the plant samples from serpentine habitats in comparison with the samples from calcareous habitats, which is an indicator of one of the mechanisms of adaptation to the serpentine habitat conditions.
Categories of Large Numbers in Line Estimation
ERIC Educational Resources Information Center
Landy, David; Charlesworth, Arthur; Ottmar, Erin
2017-01-01
How do people stretch their understanding of magnitude from the experiential range to the very large quantities and ranges important in science, geopolitics, and mathematics? This paper empirically evaluates how and whether people make use of numerical categories when estimating relative magnitudes of numbers across many orders of magnitude. We…
27 CFR 41.11 - Meaning of terms.
Code of Federal Regulations, 2010 CFR
2010-04-01
... be smoked. Cigar. Any roll of tobacco wrapped in leaf tobacco or in any substance containing tobacco... mean that the bonded manufacturer has ascertained the quantity and kind (small cigars, large cigars... tobacco products and the sale price of large cigars being shipped to the United States; that adequate bond...
Surface Elevation Change And Vertical Accretion In Created Mangroves In Tampa Bay, Florida, Usa
Mangroves protect coastlines, provide faunal habitat, and store large quantities of carbon (C). In South Florida and other parts of the Gulf of Mexico, large wetland areas, including mangrove forests, have been removed, degraded, or damaged. Wetland creation efforts have been use...
Control of decay in bolts and logs of northern hardwoods during storage
Theodore C. Scheffer; T. W. Jones
1953-01-01
Many wood-using plants in the Northeast store large quantities of hardwood logs for rather long periods. Sometimes a large volume of the wood is spoiled by decay during the storage period. A number of people have asked: "How can we prevent this loss?"
Generalized ensemble theory with non-extensive statistics
NASA Astrophysics Data System (ADS)
Shen, Ke-Ming; Zhang, Ben-Wei; Wang, En-Ke
2017-12-01
The non-extensive canonical ensemble theory is reconsidered with the method of Lagrange multipliers by maximizing Tsallis entropy, with the constraint that the normalized term of Tsallis' q -average of physical quantities, the sum ∑ pjq, is independent of the probability pi for Tsallis parameter q. The self-referential problem in the deduced probability and thermal quantities in non-extensive statistics is thus avoided, and thermodynamical relationships are obtained in a consistent and natural way. We also extend the study to the non-extensive grand canonical ensemble theory and obtain the q-deformed Bose-Einstein distribution as well as the q-deformed Fermi-Dirac distribution. The theory is further applied to the generalized Planck law to demonstrate the distinct behaviors of the various generalized q-distribution functions discussed in literature.
NASA Astrophysics Data System (ADS)
Rodriguez, M.; Brualla, L.
2018-04-01
Monte Carlo simulation of radiation transport is computationally demanding to obtain reasonably low statistical uncertainties of the estimated quantities. Therefore, it can benefit in a large extent from high-performance computing. This work is aimed at assessing the performance of the first generation of the many-integrated core architecture (MIC) Xeon Phi coprocessor with respect to that of a CPU consisting of a double 12-core Xeon processor in Monte Carlo simulation of coupled electron-photonshowers. The comparison was made twofold, first, through a suite of basic tests including parallel versions of the random number generators Mersenne Twister and a modified implementation of RANECU. These tests were addressed to establish a baseline comparison between both devices. Secondly, through the p DPM code developed in this work. p DPM is a parallel version of the Dose Planning Method (DPM) program for fast Monte Carlo simulation of radiation transport in voxelized geometries. A variety of techniques addressed to obtain a large scalability on the Xeon Phi were implemented in p DPM. Maximum scalabilities of 84 . 2 × and 107 . 5 × were obtained in the Xeon Phi for simulations of electron and photon beams, respectively. Nevertheless, in none of the tests involving radiation transport the Xeon Phi performed better than the CPU. The disadvantage of the Xeon Phi with respect to the CPU owes to the low performance of the single core of the former. A single core of the Xeon Phi was more than 10 times less efficient than a single core of the CPU for all radiation transport simulations.
Pan, Long; Liu, Yi-Tao; Xie, Xu-Ming; Ye, Xiong-Ying
2016-12-01
To obtain 2D materials with large quantity, low cost, and little pollution, liquid-phase exfoliation of their bulk form in water is a particularly fascinating concept. However, the current strategies for water-borne exfoliation exclusively employ stabilizers, such as surfactants, polymers, or inorganic salts, to minimize the extremely high surface energy of these nanosheets and stabilize them by steric repulsion. It is worth noting, however, that the remaining impurities inevitably bring about adverse effects to the ultimate performances of 2D materials. Here, a facile and green route to large-scale production of impurity-free aqueous solutions of WS 2 nanosheets is reported by direct exfoliation in water. Crucial parameters such as initial concentration, sonication time, centrifugation speed, and centrifugation time are systematically evaluated to screen out an optimized condition for scaling up. Statistics based on morphological characterization prove that substantial fraction (66%) of the obtained WS 2 nanosheets are one to five layers. X-ray diffraction and Raman characterizations reveal a high quality with few, if any, structural distortions. The water-borne exfoliation route opens up new opportunities for easy, clean processing of WS 2 -based film devices that may shine in the fields of, e.g., energy storage and functional nanocomposites owing to their excellent electrochemical, mechanical, and thermal properties. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Capturing the Large Scale Behavior of Many Particle Systems Through Coarse-Graining
NASA Astrophysics Data System (ADS)
Punshon-Smith, Samuel
This dissertation is concerned with two areas of investigation: the first is understanding the mathematical structures behind the emergence of macroscopic laws and the effects of small scales fluctuations, the second involves the rigorous mathematical study of such laws and related questions of well-posedness. To address these areas of investigation the dissertation involves two parts: Part I concerns the theory of coarse-graining of many particle systems. We first investigate the mathematical structure behind the Mori-Zwanzig (projection operator) formalism by introducing two perturbative approaches to coarse-graining of systems that have an explicit scale separation. One concerns systems with little dissipation, while the other concerns systems with strong dissipation. In both settings we obtain an asymptotic series of `corrections' to the limiting description which are small with respect to the scaling parameter, these corrections represent the effects of small scales. We determine that only certain approximations give rise to dissipative effects in the resulting evolution. Next we apply this framework to the problem of coarse-graining the locally conserved quantities of a classical Hamiltonian system. By lumping conserved quantities into a collection of mesoscopic cells, we obtain, through a series of approximations, a stochastic particle system that resembles a discretization of the non-linear equations of fluctuating hydrodynamics. We study this system in the case that the transport coefficients are constant and prove well-posedness of the stochastic dynamics. Part II concerns the mathematical description of models where the underlying characteristics are stochastic. Such equations can model, for instance, the dynamics of a passive scalar in a random (turbulent) velocity field or the statistical behavior of a collection of particles subject to random environmental forces. First, we study general well-posedness properties of stochastic transport equation with rough diffusion coefficients. Our main result is strong existence and uniqueness under certain regularity conditions on the coefficients, and uses the theory of renormalized solutions of transport equations adapted to the stochastic setting. Next, in a work undertaken with collaborator Scott-Smith we study the Boltzmann equation with a stochastic forcing. The noise describing the forcing is white in time and colored in space and describes the effects of random environmental forces on a rarefied gas undergoing instantaneous, binary collisions. Under a cut-off assumption on the collision kernel and a coloring hypothesis for the noise coefficients, we prove the global existence of renormalized (DiPerna/Lions) martingale solutions to the Boltzmann equation for large initial data with finite mass, energy, and entropy. Our analysis includes a detailed study of weak martingale solutions to a class of linear stochastic kinetic equations. Tightness of the appropriate quantities is proved by an extension of the Skorohod theorem to non-metric spaces.
Weighting factors for radiation quality: how to unite the two current concepts.
Kellerer, Albrecht M
2004-01-01
The quality factor, Q(L), used to be the universal weighting factor to account for radiation quality, until--in its 1991 Recommendations--the ICRP established a dichotomy between 'computable' and 'measurable' quantities. The new concept of the radiation weighting factor, w(R), was introduced for use with the 'computable' quantities, such as the effective dose, E. At the same time, the application of Q(L) was restricted to 'measurable' quantities, such as the operational quantities ambient dose equivalent or personal dose equivalent. The result has been a dual system of incoherent dosimetric quantities. The most conspicuous inconsistency resulted for neutrons, for which the new concept of wR had been primarily designed. While its definition requires an accounting for the gamma rays produced by neutron capture in the human body, this effect is not adequately reflected in the numerical values of wR, which are now suitable for mice, but are--at energies of the incident neutrons below 1 MeV--conspicuously too large for man. A recent Report 92 to ICRP has developed a proposal to correct the current imbalance and to define a linkage between the concepts Q(L) and wR. The proposal is here considered within a broader assessment of the rationale that led to the current dual system of dosimetric quantities.
Noroozi, Monir; Zakaria, Azmi; Radiman, Shahidan; Abdul Wahab, Zaidan
2016-01-01
In this paper, we report how few layers graphene that can be produced in large quantity with low defect ratio from exfoliation of graphite by using a high intensity probe sonication in water containing liquid hand soap and PVP. It was founded that the graphene powder obtained by this simple exfoliation method after the heat treatment had an excellent exfoliation into a single or layered graphene sheets. The UV-visible spectroscopy, FESEM, TEM, X-ray powder diffraction and Raman spectroscopy was used to analyse the graphene product. The thermal diffusivity of the samples was analysed using a highly accurate thermal-wave cavity photothermal technique. The data obtained showed excellent enhancement in the thermal diffusivity of the graphene dispersion. This well-dispersed graphene was then used to fabricate an electrically conductive polymer-graphene film composite. The results demonstrated that this low cost and environmental friendly technique allowed to the production of high quality layered graphene sheets, improved the thermal and electrical properties. This may find use in the wide range of applications based on graphene.
Noroozi, Monir; Zakaria, Azmi; Radiman, Shahidan; Abdul Wahab, Zaidan
2016-01-01
In this paper, we report how few layers graphene that can be produced in large quantity with low defect ratio from exfoliation of graphite by using a high intensity probe sonication in water containing liquid hand soap and PVP. It was founded that the graphene powder obtained by this simple exfoliation method after the heat treatment had an excellent exfoliation into a single or layered graphene sheets. The UV-visible spectroscopy, FESEM, TEM, X-ray powder diffraction and Raman spectroscopy was used to analyse the graphene product. The thermal diffusivity of the samples was analysed using a highly accurate thermal-wave cavity photothermal technique. The data obtained showed excellent enhancement in the thermal diffusivity of the graphene dispersion. This well-dispersed graphene was then used to fabricate an electrically conductive polymer-graphene film composite. The results demonstrated that this low cost and environmental friendly technique allowed to the production of high quality layered graphene sheets, improved the thermal and electrical properties. This may find use in the wide range of applications based on graphene. PMID:27064575
Optimization and characterization of gelatin and chitosan extracted from fish and shrimp waste
NASA Astrophysics Data System (ADS)
Ait Boulahsen, M.; Chairi, H.; Laglaoui, A.; Arakrak, A.; Zantar, S.; Bakkali, M.; Hassani, M.
2018-05-01
Fish and seafood processing industries generate large quantities of waste which are at the origin of several environmental, economic and social problems. However fish waste could contain high value-added substances such as biopolymers. This work focuses on optimizing the gelatin and chitosan extraction from tilapia fish skins and shrimp shells respectively. The gelatin extraction process was optimized using alkali acid treatment prior to thermal hydrolysis. Three different acids were tested at different concentrations. Chitosan was obtained after acid demineralization followed by simultaneous hydrothermal deproteinization and deacetylation by an alkali treatment with different concentrations of HCl and NaOH. The extracted gelatin and chitosan with the highest yield were characterized by determining their main physicochemical properties (Degree of deacetylation, viscosity, pH, moisture and ash content). Results show a significant influence of the acid type and concentration on the extraction yield of gelatin and chitosan, with an average yield of 12.24% and 3.85% respectively. Furthermore, the obtained physicochemical properties of both extracted gelatin and chitosan were within the recommended standard values of the commercial ones used in the industry.
NASA Technical Reports Server (NTRS)
Dahlback, Arne; Stamnes, Knut
1991-01-01
Accurate computation of atmospheric photodissociation and heating rates is needed in photochemical models. These quantities are proportional to the mean intensity of the solar radiation penetrating to various levels in the atmosphere. For large solar zenith angles a solution of the radiative transfer equation valid for a spherical atmosphere is required in order to obtain accurate values of the mean intensity. Such a solution based on a perturbation technique combined with the discrete ordinate method is presented. Mean intensity calculations are carried out for various solar zenith angles. These results are compared with calculations from a plane parallel radiative transfer model in order to assess the importance of using correct geometry around sunrise and sunset. This comparison shows, in agreement with previous investigations, that for solar zenith angles less than 90 deg adequate solutions are obtained for plane parallel geometry as long as spherical geometry is used to compute the direct beam attenuation; but for solar zenith angles greater than 90 deg this pseudospherical plane parallel approximation overstimates the mean intensity.
Automotive sulfate emission data.
Somers, J H
1975-01-01
This paper discusses automotive sulfate emission results obtained by the Office of Mobile Source Air Pollution Control of EPA, General Motors, Ford, Chrysler, and Esso. This work has been directed towards obtaining sulfate emission factors for cars with and without catalyst. While the EPA and Chrysler investigations have found significant sulfate formation in noncatalyst cars, GM, Ford, and Esso have found only trace levels from noncatalyst cars. All of these investigators agree that much higher quantities of sulfate are emitted from catalyst cars. The work done to date shows pelleted catalysts to have much lower sulfate emissions over the low speed-EPA Federal Test Procedures than monolith catalysts. This is probably due to temporary storage of sulfates on the catalyst due to chemical interaction with the alumina pellets. The sulfate compounds are, to a large degree, emitted later under higher speed conditions which result in higher catalyst temperatures which decompose the alumina salt. Future work will be directed towards further elucidation of this storage mechanism as well as determining in detail how factors such as air injection rate and catalyst location affect sulfate emissions. PMID:50932
NASA Astrophysics Data System (ADS)
Dragoni, Daniele; Daff, Thomas D.; Csányi, Gábor; Marzari, Nicola
2018-01-01
We show that the Gaussian Approximation Potential (GAP) machine-learning framework can describe complex magnetic potential energy surfaces, taking ferromagnetic iron as a paradigmatic challenging case. The training database includes total energies, forces, and stresses obtained from density-functional theory in the generalized-gradient approximation, and comprises approximately 150,000 local atomic environments, ranging from pristine and defected bulk configurations to surfaces and generalized stacking faults with different crystallographic orientations. We find the structural, vibrational, and thermodynamic properties of the GAP model to be in excellent agreement with those obtained directly from first-principles electronic-structure calculations. There is good transferability to quantities, such as Peierls energy barriers, which are determined to a large extent by atomic configurations that were not part of the training set. We observe the benefit and the need of using highly converged electronic-structure calculations to sample a target potential energy surface. The end result is a systematically improvable potential that can achieve the same accuracy of density-functional theory calculations, but at a fraction of the computational cost.
a Method of Generating dem from Dsm Based on Airborne Insar Data
NASA Astrophysics Data System (ADS)
Lu, W.; Zhang, J.; Xue, G.; Wang, C.
2018-04-01
Traditional methods of terrestrial survey to acquire DEM cannot meet the requirement of acquiring large quantities of data in real time, but the DSM can be quickly obtained by using the dual antenna synthetic aperture radar interferometry and the DEM generated by the DSM is more fast and accurate. Therefore it is most important to acquire DEM from DSM based on airborne InSAR data. This paper aims to the method that generate DEM from DSM accurately. Two steps in this paper are applied to acquire accurate DEM. First of all, when the DSM is generated by interferometry, unavoidable factors such as overlay and shadow will produce gross errors to affect the data accuracy, so the adaptive threshold segmentation method is adopted to remove the gross errors and the threshold is selected according to the coherence of the interferometry. Secondly DEM will be generated by the progressive triangulated irregular network densification filtering algorithm. Finally, experimental results are compared with the existing high-precision DEM results. The results show that this method can effectively filter out buildings, vegetation and other objects to obtain the high-precision DEM.
Microphytobenthos in ecotoxicology: a review of the use of marine benthic diatoms in bioassays.
Araújo, Cristiano V M; Blasco, Julián; Moreno-Garrido, Ignacio
2010-08-01
Contamination in coastal zones is an increasing problem that adversely affects biological diversity and the functioning of coastal ecosystems. Sediment is an important compartment of these zones since large quantities of diverse contaminants can accumulate there. Whole-sediment toxicity assays are of increasing importance, and several assay methods using mainly invertebrates have been developed. However, an important part of the benthic community, the microphytobenthos (represented principally by benthic diatoms and cyanobacteria), has surprisingly been neglected. Recently, comprehensive studies have been conducted using benthic marine microalgae with the object of establishing a toxicity assay method for sediment samples. The main results published to date in the literature and obtained by our own team have been compiled and are discussed in this review. The value and feasibility of using certain organisms of the microphytobenthos group in ecotoxicology studies are also discussed, and a sediment quality guideline based on multivariate procedure has been derived from data obtained in previous studies. Finally, future perspectives for research in this field are discussed. Copyright 2010 Elsevier Ltd. All rights reserved.
Effect of nylon fiber on mechanical properties of cement based mortar
NASA Astrophysics Data System (ADS)
Hanif, I. M.; Syuhaili, M. R. Noor; Hasmori, M. F.; Shahmi, S. M.
2017-11-01
An investigation has been carried out to study the effect of nylon fiber on the mechanical properties of cement based mortar after receiving large quantities of nylon waste. Subsequently, this research was conducted to compare the compressive, tensile and flexural strength of normal cement based mortar with nylon fiber cement based mortar. All samples using constant water-cement ratio of 0.63 and three different percentages of nylon fiber were added in the mixture during the samples preparation period which consists of 0.5%, 1.5% and 2.5% by total weight of cement based mortar. The results obtained with different nylon percentage marked an increases in compressive strength (up to 17%), tensile strength (up to 21%) and flexural strength (up to 13%) when compared with control cement based mortar samples. Therefore, the results obtained from this study shows that by using nylon fiber as additive material can improve the mechanical properties of the cement based mortar and at the same time produce a good sustainable product that can protects and conserve the marine environment.
Obtaining high-resolution stage forecasts by coupling large-scale hydrologic models with sensor data
NASA Astrophysics Data System (ADS)
Fries, K. J.; Kerkez, B.
2017-12-01
We investigate how "big" quantities of distributed sensor data can be coupled with a large-scale hydrologic model, in particular the National Water Model (NWM), to obtain hyper-resolution forecasts. The recent launch of the NWM provides a great example of how growing computational capacity is enabling a new generation of massive hydrologic models. While the NWM spans an unprecedented spatial extent, there remain many questions about how to improve forecast at the street-level, the resolution at which many stakeholders make critical decisions. Further, the NWM runs on supercomputers, so water managers who may have access to their own high-resolution measurements may not readily be able to assimilate them into the model. To that end, we ask the question: how can the advances of the large-scale NWM be coupled with new local observations to enable hyper-resolution hydrologic forecasts? A methodology is proposed whereby the flow forecasts of the NWM are directly mapped to high-resolution stream levels using Dynamical System Identification. We apply the methodology across a sensor network of 182 gages in Iowa. Of these sites, approximately one third have shown to perform well in high-resolution flood forecasting when coupled with the outputs of the NWM. The quality of these forecasts is characterized using Principal Component Analysis and Random Forests to identify where the NWM may benefit from new sources of local observations. We also discuss how this approach can help municipalities identify where they should place low-cost sensors to most benefit from flood forecasts of the NWM.
Fauchald, Per; Langeland, Knut; Ims, Rolf A.; Yoccoz, Nigel G.; Bråthen, Kari Anne
2014-01-01
The spatial and temporal distribution of forage quality is among the most central factors affecting herbivore habitat selection. Yet, for high latitude areas, forage quantity has been found to be more important than quality. Studies on large ungulate foraging patterns are faced with methodological challenges in both assessing animal movements at the scale of forage distribution, and in assessing forage quality with relevant metrics. Here we use first-passage time analyses to assess how reindeer movements relate to forage quality and quantity measured as the phenology and cover of growth forms along reindeer tracks. The study was conducted in a high latitude ecosystem dominated by low-palatable growth forms. We found that the scale of reindeer movement was season dependent, with more extensive area use as the summer season advanced. Small-scale movement in the early season was related to selection for younger stages of phenology and for higher abundances of generally phenologically advanced palatable growth forms (grasses and deciduous shrubs). Also there was a clear selection for later phenological stages of the most dominant, yet generally phenologically slow and low-palatable growth form (evergreen shrubs). As the summer season advanced only quantity was important, with selection for higher quantities of one palatable growth form and avoidance of a low palatable growth form. We conclude that both forage quality and quantity are significant predictors to habitat selection by a large herbivore at high latitude. The early season selectivity reflected that among dominating low palatability growth forms there were palatable phenological stages and palatable growth forms available, causing herbivores to be selective in their habitat use. The diminishing selectivity and the increasing scale of movement as the season developed suggest a response by reindeer to homogenized forage availability of low quality. PMID:24972188
Iversen, Marianne; Fauchald, Per; Langeland, Knut; Ims, Rolf A; Yoccoz, Nigel G; Bråthen, Kari Anne
2014-01-01
The spatial and temporal distribution of forage quality is among the most central factors affecting herbivore habitat selection. Yet, for high latitude areas, forage quantity has been found to be more important than quality. Studies on large ungulate foraging patterns are faced with methodological challenges in both assessing animal movements at the scale of forage distribution, and in assessing forage quality with relevant metrics. Here we use first-passage time analyses to assess how reindeer movements relate to forage quality and quantity measured as the phenology and cover of growth forms along reindeer tracks. The study was conducted in a high latitude ecosystem dominated by low-palatable growth forms. We found that the scale of reindeer movement was season dependent, with more extensive area use as the summer season advanced. Small-scale movement in the early season was related to selection for younger stages of phenology and for higher abundances of generally phenologically advanced palatable growth forms (grasses and deciduous shrubs). Also there was a clear selection for later phenological stages of the most dominant, yet generally phenologically slow and low-palatable growth form (evergreen shrubs). As the summer season advanced only quantity was important, with selection for higher quantities of one palatable growth form and avoidance of a low palatable growth form. We conclude that both forage quality and quantity are significant predictors to habitat selection by a large herbivore at high latitude. The early season selectivity reflected that among dominating low palatability growth forms there were palatable phenological stages and palatable growth forms available, causing herbivores to be selective in their habitat use. The diminishing selectivity and the increasing scale of movement as the season developed suggest a response by reindeer to homogenized forage availability of low quality.
Drooling in Parkinson's disease: a novel tool for assessment of swallow frequency.
Marks, L; Weinreich, J
2001-01-01
A non-invasive way to obtain objective measurements of swallowing frequency and thus indirectly, drooling was required as part of the study 'Drooling in Parkinson's disease: objective measurement and response to therapy'. A hard disk, digital recorder was developed, for use on a laptop computer, which was capable of collecting large quantities of swallowing data from an anticipated 40 patients and 10 controls. An electric microphone was taped to the subjects' larynx for recording the swallow sounds when drinking 150 ml of water and at rest for 30 minutes. The software provides an accurate visual display of the audio-signal allowing the researcher easy access to any segment of the recording and to mark and extract the swallow events, so that swallow frequency may be efficiently and accurately ascertained. Preliminary results are presented.
Modeling Adsorption Based Filters (Bio-remediation of Heavy Metal Contaminated Water)
NASA Astrophysics Data System (ADS)
McCarthy, Chris
I will discuss kinetic models of adsorption, as well as models of filters based on those mechanisms. These mathematical models have been developed in support of our interdisciplinary lab group, which is centered at BMCC/CUNY (City University of New York). Our group conducts research into bio-remediation of heavy metal contaminated water via filtration. The filters are constructed out of biomass, such as spent tea leaves. The spent tea leaves are available in large quantities as a result of the industrial production of tea beverages. The heavy metals bond with the surfaces of the tea leaves (adsorption). The models involve differential equations, stochastic methods, and recursive functions. I will compare the models' predictions to data obtained from computer simulations and experimentally by our lab group. Funding: CUNY Collaborative Incentive Research Grant (Round 12); CUNY Research Scholars Program.
Flotation-separation of aluminum from some water samples using powdered marble waste and oleic acid.
Ghazy, Shaban el-Sayed; Samra, Salem el-Sayed; Mahdy, Abd el-Fattah Mohammed; el-Morsy, Sherin Mohammed
2003-10-01
Bench-scale experiments were conducted in the laboratory, aiming to remove aluminum from water. They were based on the use of powdered marble wastes (PMW), which are inexpensive and produced in large quantity, and thus potentially cause environmental problems, as an effective inorganic sorbent and oleic acid (HOL) as surfactant. The main parameters (solution pHs, sorbent, surfactant and aluminum concentrations, shaking time, ionic strength and the presence of foreign ions) that influence the sorptive-flotation process were examined. Good results were obtained under the optimum conditions, for which nearly 100% of aluminum at pH 7 and at room temperature (approximately 25 degrees C) was removed. The procedure was successfully applied to the recovery of aluminum spiked to some natural water samples. Moreover, a sorption and flotation mechanism is suggested.
Bathen, Marianne Etzelmüller; Linder, Jacob
2017-01-01
We theoretically consider the spin Seebeck effect, the charge Seebeck coefficient, and the thermoelectric figure of merit in superconducting hybrid structures including either magnetic textures or intrinsic spin-orbit coupling. We demonstrate that large magnitudes for all these quantities are obtainable in Josephson-based systems with either zero or a small externally applied magnetic field. This provides an alternative to the thermoelectric effects generated in high-field (~1 T) superconducting hybrid systems, which were recently experimentally demonstrated. The systems studied contain either conical ferromagnets, spin-active interfaces, or spin-orbit coupling. We present a framework for calculating the linear thermoelectric response for both spin and charge of a system upon applying temperature and voltage gradients based on quasiclassical theory which allows for arbitrary spin-dependent textures and fields to be conveniently incorporated. PMID:28139667
Biodiesel production from heterotrophic microalgal oil.
Miao, Xiaoling; Wu, Qingyu
2006-04-01
The present study introduced an integrated method for the production of biodiesel from microalgal oil. Heterotrophic growth of Chlorella protothecoides resulted in the accumulation of high lipid content (55%) in cells. Large amount of microalgal oil was efficiently extracted from these heterotrophic cells by using n-hexane. Biodiesel comparable to conventional diesel was obtained from heterotrophic microalgal oil by acidic transesterification. The best process combination was 100% catalyst quantity (based on oil weight) with 56:1 molar ratio of methanol to oil at temperature of 30 degrees C, which reduced product specific gravity from an initial value of 0.912 to a final value of 0.8637 in about 4h of reaction time. The results suggested that the new process, which combined bioengineering and transesterification, was a feasible and effective method for the production of high quality biodiesel from microalgal oil.
VizieR Online Data Catalog: BVI photometry of LMC bar variables (Di Fabrizio+, 2005)
NASA Astrophysics Data System (ADS)
di Fabrizio, L.; Clementini, G.; Maio, M.; Bragaglia, A.; Carretta, E.; Gratton, R.; Montegriffo, P.; Zoccali, M.
2005-01-01
We present the Johnson-Cousins B,V and I time series data obtained for 162 variable stars (135 RR Lyrae, 4 candidate Anomalous Cepheids, 11 Classical Cepheids, 11 eclipsing binaries and 1 delta Scuti star) in two 13x13 square arcmin areas close to the bar of the Large Magellanic Cloud. The photometric observations presented in this paper were carried out at the 1.54m Danish telescope located in La Silla, Chile, on the nights 4-7 January 1999, UT, and 23-24 January 2001, UT, respectively. In the paper we give coordinates, finding charts, periods, epochs, amplitudes, and mean quantities (intensity- and magnitude-averaged luminosities) of the variables with full coverage of the light variations, along with a discussion of the pulsation properties of the RR Lyrae stars in the sample. (8 data files).
Ocean Chlorophyll Studies from a U-2 Aircraft Platform
NASA Technical Reports Server (NTRS)
Kim, H. H.; Mcclain, C. R.; Blaine, L. R.; Hart, W. D.; Atkinson, L. P.; Yoder, J. A.
1979-01-01
Chlorophyll gradient maps of large ocean areas were generated from U-2 ocean color scanner data obtained over test sites in the Pacific and Atlantic Oceans. The delineation of oceanic features using the upward radiant intensity relies on an analysis method which presupposes that radiation backscattered from the atmosphere and ocean surface can be properly modeled using a measurement made at 778 nm. An estimation of the chlorophyll concentration was performed by properly ratioing radiances measured at 472 nm and 548 nm after removing the atmospheric effects. The correlation between the remotely sensed data and in-situ surface chlorophyll measurements was validated in two sets of data. The results show that the correlation between the in-situ measured chlorophyll and the derived quantity is a negative exponential function and the correlation coefficient was calculated to be -0.965.
A model for ionic polymer metal composites as sensors
NASA Astrophysics Data System (ADS)
Bonomo, C.; Fortuna, L.; Giannone, P.; Graziani, S.; Strazzeri, S.
2006-06-01
This paper introduces a comprehensive model of sensors based on ionic polymer metal composites (IPMCs) working in air. Significant quantities ruling the sensing properties of IPMC-based sensors are taken into account and the dynamics of the sensors are modelled. A large amount of experimental evidence is given for the excellent agreement between estimations obtained using the proposed model and the observed signals. Furthermore, the effect of sensor scaling is investigated, giving interesting support to the activities involved in the design of sensing devices based on these novel materials. We observed that the need for a wet environment is not a key issue for IPMC-based sensors to work well. This fact allows us to put IPMC-based sensors in a totally different light to the corresponding actuators, showing that sensors do not suffer from the same drawbacks.
Bathen, Marianne Etzelmüller; Linder, Jacob
2017-01-31
We theoretically consider the spin Seebeck effect, the charge Seebeck coefficient, and the thermoelectric figure of merit in superconducting hybrid structures including either magnetic textures or intrinsic spin-orbit coupling. We demonstrate that large magnitudes for all these quantities are obtainable in Josephson-based systems with either zero or a small externally applied magnetic field. This provides an alternative to the thermoelectric effects generated in high-field (~1 T) superconducting hybrid systems, which were recently experimentally demonstrated. The systems studied contain either conical ferromagnets, spin-active interfaces, or spin-orbit coupling. We present a framework for calculating the linear thermoelectric response for both spin and charge of a system upon applying temperature and voltage gradients based on quasiclassical theory which allows for arbitrary spin-dependent textures and fields to be conveniently incorporated.
Presence of emerging contaminants in Natural Wetlands: L
NASA Astrophysics Data System (ADS)
Roig, P. V.; Blasco, C.; Andreu, V.; Pascual, J. A.; Rubio, J. L.; Picó, Y.
2009-04-01
A wide range of pharmaceutical compounds have been identified in the environment, and their presence is a topic of growing concern for human and ecological health. The antibiotics group are relevant in the formation of antibiotic resistances in pathogenic bacteria. Other pharmaceuticals, such as analgesics and lipid regulators, are consumed in large quantities and have been frequently found in high concentrations in several environmental compartments. ĹAlbufera Lake (Valencia, Spain) is a marsh area of a great interest because it is the habitat of a large quantity of unique species of flora and fauna, and a zone of refuge, feeding and breeding for a large number of migratory birds, because of that, was included in the RAMSAR network. However, this area is threatened by the tourist industry; urban, industrial, and agricultural pressures; and the disappearance of its marshes by transformation to rice or orchard fields. The aim of this work was to establish the occurrence and distribution of pharmaceuticals in water, as indicative of human sewage pouring into the lake. A representative set of pharmaceuticals of different therapeutic classes was chosen for this purpose, including: analgesics, antibiotics, anti-inflammatories, β-blockers, anticonvulsants, antidepressants and lipid regulators. In April 2008 and October 2008 a total of 65 samples of water were collected, corresponding to different sampling points previously designed, and covering the most important channels that flow in to the lake. Water samples were concentrated by Solid Phase Extraction through an Oasis HLB cartridge, and subsequently eluted with methanol. Quantification was carried out by LC-MS/MS with an ESI interface. Separation was made with a Sunfire 3.5 C18 (Waters®) analytical column. When possible, two transitions were selected to obtain unambiguous confirmation. Acetaminophen (paracetamol) and carbamazepine were the pharmaceuticals that more frequently appeared in water samples, being the latter found in 63 of the 65 analyzed samples in concentrations between 0.01 g/L and 248 mg/L. Others pharmaceuticals present in less quantities were: ciprofloxacin, codeine, diazepam, fenofibrate, ibuprofen, norfloxacin, metoprolol, ofloxacin, propanolol, sulfamethoxazole and trimethoprim. These results demonstrate the incidence of these pollutants in the Natural Park of ĹAlbufera, probably because raw sewage flows into the lake from houses and industries nears its shores. Increased pollution is threatening the sustainable use of ĹAlbufera, a vital resource for this touristic area. References: [1] N. Esiobu, L. Armenta, J. Ike, Int. J. Environ. Health 12. (2002), 133. [2] D. Löffler, T. A. Ternes, J. Chromatogr. A. 1021 (2003), 133-144.
Precise and efficient evaluation of gravimetric quantities at arbitrarily scattered points in space
NASA Astrophysics Data System (ADS)
Ivanov, Kamen G.; Pavlis, Nikolaos K.; Petrushev, Pencho
2017-12-01
Gravimetric quantities are commonly represented in terms of high degree surface or solid spherical harmonics. After EGM2008, such expansions routinely extend to spherical harmonic degree 2190, which makes the computation of gravimetric quantities at a large number of arbitrarily scattered points in space using harmonic synthesis, a very computationally demanding process. We present here the development of an algorithm and its associated software for the efficient and precise evaluation of gravimetric quantities, represented in high degree solid spherical harmonics, at arbitrarily scattered points in the space exterior to the surface of the Earth. The new algorithm is based on representation of the quantities of interest in solid ellipsoidal harmonics and application of the tensor product trigonometric needlets. A FORTRAN implementation of this algorithm has been developed and extensively tested. The capabilities of the code are demonstrated using as examples the disturbing potential T, height anomaly ζ , gravity anomaly Δ g , gravity disturbance δ g , north-south deflection of the vertical ξ , east-west deflection of the vertical η , and the second radial derivative T_{rr} of the disturbing potential. After a pre-computational step that takes between 1 and 2 h per quantity, the current version of the software is capable of computing on a standard PC each of these quantities in the range from the surface of the Earth up to 544 km above that surface at speeds between 20,000 and 40,000 point evaluations per second, depending on the gravimetric quantity being evaluated, while the relative error does not exceed 10^{-6} and the memory (RAM) use is 9.3 GB.
Ion composition and energy distribution during 10 magnetic storms
NASA Technical Reports Server (NTRS)
Lennartsson, W.; Sharp, R. D.; Shelley, E. G.; Johnson, R. G.; Balsiger, H.
1981-01-01
Data from the plasma composition experiment of ISEE 1 are used to investigate the relative quantities and energy characteristics of H(+), He(++), He(+), and O(+) ions in the near-equatorial magnetosphere during magnetic storm conditions. The ions in the study had energies between 0.1 and 17 keV/e and pitch angles between 45 and 135 deg. The data were obtained during 10 storms, for the most part at or immediately following the peak Dst, covering all major local time sectors and geocentric distances between 2 and 15 earth radii. The ion fluxes are averaged over the spacecraft spin angle and over time for periods ranging from about 20 min close to the earth to more than an hour in most distant regions. The inferred 'isotropic' number densities are characterized by a large to dominant fraction of terrestrial ions throughout the energy range covered. The data are found to be consistent with a terrestrial origin for all of the O(+), most of the He(+), and a large but varying fraction of the H(+), whereas the He(++) and part of the H(+) appear to be of solar wind origin.
Mesons in strong magnetic fields: (I) General analyses
Hattori, Koichi; Kojo, Toru; Su, Nan
2016-03-21
Here, we study properties of neutral and charged mesons in strong magnetic fields |eB| >> Λ 2 QCD with Λ QCD being the QCD renormalization scale. Assuming long-range interactions, we examine magnetic-field dependences of various quantities such as the constituent quark mass, chiral condensate, meson spectra, and meson wavefunctions by analyzing the Schwinger–Dyson and Bethe–Salpeter equations. Based on the density of states obtained from these analyses, we extend the hadron resonance gas (HRG) model to investigate thermodynamics at large B. As B increases the meson energy behaves as a slowly growing function of the meson's transverse momenta, and thus amore » large number of meson states is accommodated in the low energy domain; the density of states at low temperature is proportional to B 2. This extended transverse phase space in the infrared regime significantly enhances the HRG pressure at finite temperature, so that the system reaches the percolation or chiral restoration regime at lower temperature compared to the case without a magnetic field; this simple picture would offer a gauge invariant and intuitive explanation of the inverse magnetic catalysis.« less
Production of brown and black pigments by using flotation waste from copper slag.
Ozel, Emel; Turan, Servet; Coruh, Semra; Ergun, Osman Nuri
2006-04-01
One of the major problems in copper-producing countries is the treatment of the large amount of copper slag or copper flotation waste generated from copper slag which contains significant amounts of heavy metals such as Cu, Zn, Pb and Co. Dumping or disposal of such large quantities of flotation waste from copper slag causes environmental and space problems. In this study, the treatment of flotation waste from copper slag by a thermal method and its use as an iron source in the production of inorganic brown and black pigments that are used in the ceramic industry were investigated. The pigments were produced by calcining different amounts of flotation waste and chromite, Cr2O3, ZnO and CoO mixtures. The pigments obtained were added to transparent ceramic glazes and porcelainized tile bodies. Their colours were defined by L*a*b* measurements with a spectrophotometer. The results showed that flotation waste from copper slag could be used as an iron source to produce brown and black pigments in both ceramic body and glazes.
New Precise Measurement of the Hyperfine Splitting of Positronium
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ishida, A., E-mail: ishida@icepp.s.u-tokyo.ac.jp
Positronium (Ps) is an ideal system for precision test of bound state quantum electrodynamics. The hyperfine splitting (HFS) of the ground state of Ps, which is one of the most precisely tested quantity, has a large discrepancy of 16 ppm (4.5 σ) between previous experiments and theoretical calculation up to O(α{sup 3}lnα{sup −1}) and part of O(α{sup 3}) corrections. A new experiment which reduces possible systematic uncertainties of Ps thermalization effect and nonuniformity of magnetic field was performed. It revealed that the Ps thermalization effect was as large as 10 ± 2 ppm. Treating the thermalization effect correctly, a newmore » result of 203.3942 ± 0.0016(stat., 8.0 ppm) ± 0.0013(sys., 6.4 ppm) GHz was obtained. This result is consistent with theory within 1.1 σ, whereas it disfavors the previous experimental result by 2.6 σ. It shows that the Ps thermalization effect is crucial for precision measurement of HFS. Future prospects for improved precision are briefly discussed.« less
Interactive and coordinated visualization approaches for biological data analysis.
Cruz, António; Arrais, Joel P; Machado, Penousal
2018-03-26
The field of computational biology has become largely dependent on data visualization tools to analyze the increasing quantities of data gathered through the use of new and growing technologies. Aside from the volume, which often results in large amounts of noise and complex relationships with no clear structure, the visualization of biological data sets is hindered by their heterogeneity, as data are obtained from different sources and contain a wide variety of attributes, including spatial and temporal information. This requires visualization approaches that are able to not only represent various data structures simultaneously but also provide exploratory methods that allow the identification of meaningful relationships that would not be perceptible through data analysis algorithms alone. In this article, we present a survey of visualization approaches applied to the analysis of biological data. We focus on graph-based visualizations and tools that use coordinated multiple views to represent high-dimensional multivariate data, in particular time series gene expression, protein-protein interaction networks and biological pathways. We then discuss how these methods can be used to help solve the current challenges surrounding the visualization of complex biological data sets.
A transthyretin-related protein is functionally expressed in Herbaspirillum seropedicae.
Matiollo, Camila; Vernal, Javier; Ecco, Gabriela; Bertoldo, Jean Borges; Razzera, Guilherme; de Souza, Emanuel M; Pedrosa, Fábio O; Terenzi, Hernán
2009-10-02
Transthyretin-related proteins (TRPs) constitute a family of proteins structurally related to transthyretin (TTR) and are found in a large range of bacterial, fungal, plant, invertebrate, and vertebrate species. However, it was recently recognized that both prokaryotic and eukaryotic members of this family are not functionally related to transthyretins. TRPs are in fact involved in the purine catabolic pathway and function as hydroxyisourate hydrolases. An open reading frame encoding a protein similar to the Escherichia coli TRP was identified in Herbaspirillum seropedicae genome (Hs_TRP). It was cloned, overexpressed in E. coli, and purified to homogeneity. Mass spectrometry data confirmed the identity of this protein, and circular dichroism spectrum indicated a predominance of beta-sheet structure, as expected for a TRP. We have demonstrated that Hs_TRP is a 5-hydroxyisourate hydrolase and by site-directed mutagenesis the importance of three conserved catalytic residues for Hs_TRP activity was further confirmed. The production of large quantities of this recombinant protein opens up the possibility of obtaining its 3D-structure and will help further investigations into purine catabolism.
Formation of Enhanced Uniform Chiral Fields in Symmetric Dimer Nanostructures
Tian, Xiaorui; Fang, Yurui; Sun, Mengtao
2015-01-01
Chiral fields with large optical chirality are very important in chiral molecules analysis, sensing and other measurements. Plasmonic nanostructures have been proposed to realize such super chiral fields for enhancing weak chiral signals. However, most of them cannot provide uniform chiral near-fields close to the structures, which makes these nanostructures not so efficient for applications. Plasmonic helical nanostructures and blocked squares have been proved to provide uniform chiral near-fields, but structure fabrication is a challenge. In this paper, we show that very simple plasmonic dimer structures can provide uniform chiral fields in the gaps with large enhancement of both near electric fields and chiral fields under linearly polarized light illumination with polarization off the dimer axis at dipole resonance. An analytical dipole model is utilized to explain this behavior theoretically. 30 times of volume averaged chiral field enhancement is gotten in the whole gap. Chiral fields with opposite handedness can be obtained simply by changing the polarization to the other side of the dimer axis. It is especially useful in Raman optical activity measurement and chiral sensing of small quantity of chiral molecule. PMID:26621558
Obtaining accurate amounts of mercury from mercury compounds via electrolytic methods
Grossman, Mark W.; George, William A.
1987-01-01
A process for obtaining pre-determined, accurate rate amounts of mercury. In one embodiment, predetermined, precise amounts of Hg are separated from HgO and plated onto a cathode wire. The method for doing this involves dissolving a precise amount of HgO which corresponds to a pre-determined amount of Hg desired in an electrolyte solution comprised of glacial acetic acid and H.sub.2 O. The mercuric ions are then electrolytically reduced and plated onto a cathode producing the required pre-determined quantity of Hg. In another embodiment, pre-determined, precise amounts of Hg are obtained from Hg.sub.2 Cl.sub.2. The method for doing this involves dissolving a precise amount of Hg.sub.2 Cl.sub.2 in an electrolyte solution comprised of concentrated HCl and H.sub.2 O. The mercurous ions in solution are then electrolytically reduced and plated onto a cathode wire producing the required, pre-determined quantity of Hg.
The Reliability and Stability of an Inferred Phylogenetic Tree from Empirical Data.
Katsura, Yukako; Stanley, Craig E; Kumar, Sudhir; Nei, Masatoshi
2017-03-01
The reliability of a phylogenetic tree obtained from empirical data is usually measured by the bootstrap probability (Pb) of interior branches of the tree. If the bootstrap probability is high for most branches, the tree is considered to be reliable. If some interior branches show relatively low bootstrap probabilities, we are not sure that the inferred tree is really reliable. Here, we propose another quantity measuring the reliability of the tree called the stability of a subtree. This quantity refers to the probability of obtaining a subtree (Ps) of an inferred tree obtained. We then show that if the tree is to be reliable, both Pb and Ps must be high. We also show that Ps is given by a bootstrap probability of the subtree with the closest outgroup sequence, and computer program RESTA for computing the Pb and Ps values will be presented. © The Author 2017. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.
Two opposed lateral jets injected into swirling crossflow
NASA Technical Reports Server (NTRS)
Lilley, D. G.; Mcmurry, C. B.; Ong, L. H.
1987-01-01
Experiments have been conducted to obtain the time-mean and turbulent quantities of opposed lateral jets in a low speed, nonreacting flowfield. A jet-to-crossflow velocity ratio of R = 4 was used throughout the experiments, with swirl vane angles of 0 (swirler removed), 45 and 70 degrees used with the crossflow. Flow visualization techniques used were neutrally-buoyant helium-filled soap bubbles and multispark photography in order to obtain the gross flowfield characteristics. Measurements of time-mean and turbulent quantities were obtained utilizing a six-orientation single hot-wire technique. For the nonswirling case, the jets were found not to penetrate past the test-section centerline, in contrast to the single lateral jet with the same jet-to-crossflow velocity ratio. In the swirling cases, the crossflow remains in a narrow region near the wall of the test section. The opposed jets are swept from their vertical courses into spiral trajectories close to the confining walls. Extensive results are presented in r-x plane plots.
Obtaining accurate amounts of mercury from mercury compounds via electrolytic methods
Grossman, M.W.; George, W.A.
1987-07-07
A process is described for obtaining pre-determined, accurate rate amounts of mercury. In one embodiment, predetermined, precise amounts of Hg are separated from HgO and plated onto a cathode wire. The method for doing this involves dissolving a precise amount of HgO which corresponds to a pre-determined amount of Hg desired in an electrolyte solution comprised of glacial acetic acid and H[sub 2]O. The mercuric ions are then electrolytically reduced and plated onto a cathode producing the required pre-determined quantity of Hg. In another embodiment, pre-determined, precise amounts of Hg are obtained from Hg[sub 2]Cl[sub 2]. The method for doing this involves dissolving a precise amount of Hg[sub 2]Cl[sub 2] in an electrolyte solution comprised of concentrated HCl and H[sub 2]O. The mercurous ions in solution are then electrolytically reduced and plated onto a cathode wire producing the required, pre-determined quantity of Hg. 1 fig.
Holographic black hole chemistry
Karch, Andreas; Robinson, Brandon
2015-12-14
Thermodynamic quantities associated with black holes in Anti-de Sitter space obey an interesting identity when the cosmological constant is included as one of the dynamical variables, the generalized Smarr relation. Here, we show that this relation can easily be understood from the point of view of the dual holographic field theory. It amounts to the simple statement that the extensive thermodynamic quantities of a large N gauge theory only depend on the number of colors, N, via an overall factor of N 2.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Vorobev, A.M.; Kuzmina, V.P.
A method is described for determining Pu in the presence of large quantities of U. Pu is extracted using thenoyltrifluoroacetone (TTA) and precipitated using bismuth phosphate. In contrast to U (VI), plutonium (IV) is easily separated by TTA from 1M nitric acid and lends itself to quantitative precipitation. The yield of Pu amounted to 90%. The presence of U/sup 235/ in quantities exceeding 200-fold the Pu content did not influence the determination in 10-mg specimens. The order of error was plus or minus 20%. (R.V.J.)
NASA Astrophysics Data System (ADS)
Ilgin, Irfan; Yang, I.-Sheng
2014-08-01
We show that for every qubit of quantum information, there is a well-defined notion of "the amount of energy that carries it," because it is a conserved quantity. This generalizes to larger systems and any conserved quantities: the eigenvalue spectrum of conserved charges has to be preserved while transferring quantum information. It is possible to "apparently" violate these conservations by losing a small fraction of information, but that must invoke a specific process which requires a large scale coherence. We discuss its implication regarding the black hole information paradox.
Budget of Turbulent Kinetic Energy in a Shock Wave Boundary-Layer Interaction
NASA Technical Reports Server (NTRS)
Vyas, Manan; Waindim, Mbu; Gaitonde, Datta
2016-01-01
Implicit large-eddy simulation (ILES) of a shock wave boundary-layer interaction (SBLI) was performed. Quantities present in the exact equation of the turbulent kinetic energy (TKE) transport were accumulated. These quantities will be used to calculate the components of TKE-like production, dissipation, transport, and dilatation. Correlations of these terms will be presented to study the growth and interaction between various terms. A comparison with its RANS (Reynolds-Averaged Navier-Stokes) counterpart will also be presented.
Active Subspaces of Airfoil Shape Parameterizations
NASA Astrophysics Data System (ADS)
Grey, Zachary J.; Constantine, Paul G.
2018-05-01
Design and optimization benefit from understanding the dependence of a quantity of interest (e.g., a design objective or constraint function) on the design variables. A low-dimensional active subspace, when present, identifies important directions in the space of design variables; perturbing a design along the active subspace associated with a particular quantity of interest changes that quantity more, on average, than perturbing the design orthogonally to the active subspace. This low-dimensional structure provides insights that characterize the dependence of quantities of interest on design variables. Airfoil design in a transonic flow field with a parameterized geometry is a popular test problem for design methodologies. We examine two particular airfoil shape parameterizations, PARSEC and CST, and study the active subspaces present in two common design quantities of interest, transonic lift and drag coefficients, under each shape parameterization. We mathematically relate the two parameterizations with a common polynomial series. The active subspaces enable low-dimensional approximations of lift and drag that relate to physical airfoil properties. In particular, we obtain and interpret a two-dimensional approximation of both transonic lift and drag, and we show how these approximation inform a multi-objective design problem.
Bounds on stochastic chemical kinetic systems at steady state
NASA Astrophysics Data System (ADS)
Dowdy, Garrett R.; Barton, Paul I.
2018-02-01
The method of moments has been proposed as a potential means to reduce the dimensionality of the chemical master equation (CME) appearing in stochastic chemical kinetics. However, attempts to apply the method of moments to the CME usually result in the so-called closure problem. Several authors have proposed moment closure schemes, which allow them to obtain approximations of quantities of interest, such as the mean molecular count for each species. However, these approximations have the dissatisfying feature that they come with no error bounds. This paper presents a fundamentally different approach to the closure problem in stochastic chemical kinetics. Instead of making an approximation to compute a single number for the quantity of interest, we calculate mathematically rigorous bounds on this quantity by solving semidefinite programs. These bounds provide a check on the validity of the moment closure approximations and are in some cases so tight that they effectively provide the desired quantity. In this paper, the bounded quantities of interest are the mean molecular count for each species, the variance in this count, and the probability that the count lies in an arbitrary interval. At present, we consider only steady-state probability distributions, intending to discuss the dynamic problem in a future publication.
NASA Astrophysics Data System (ADS)
Bhattacharya, Krishnakanta; Das, Ashmita; Majhi, Bibhas Ranjan
2018-06-01
We revisit the thermodynamic aspects of the scalar-tensor theory of gravity in the Jordan and in the Einstein frame. Examining the missing links of this theory carefully, we establish the thermodynamic descriptions from the conserved currents and potentials by following both the Noether and the Abbott-Deser-Tekin (ADT) formalism. With the help of conserved Noether current and potential, we define the thermodynamic quantities, which we show to be conformally invariant. Moreover, the defined quantities are shown to fit nicely in the laws of (the first and the second) black hole thermodynamics formulated by the Wald's method. We stretch the study of the conformal equivalence of the physical quantities in these two frames by following the ADT formalism. Our further study reveals that there is a connection between the ADT and the Noether conserved quantities, which signifies that the ADT approach provide the equivalent thermodynamic description in the two frames as obtained in Noether prescription. Our whole analysis is very general as the conserved Noether and ADT currents and potentials are formulated off-shell and the analysis is exempted from any prior assumption or boundary condition.
Dissimilarities of reduced density matrices and eigenstate thermalization hypothesis
NASA Astrophysics Data System (ADS)
He, Song; Lin, Feng-Li; Zhang, Jia-ju
2017-12-01
We calculate various quantities that characterize the dissimilarity of reduced density matrices for a short interval of length ℓ in a two-dimensional (2D) large central charge conformal field theory (CFT). These quantities include the Rényi entropy, entanglement entropy, relative entropy, Jensen-Shannon divergence, as well as the Schatten 2-norm and 4-norm. We adopt the method of operator product expansion of twist operators, and calculate the short interval expansion of these quantities up to order of ℓ9 for the contributions from the vacuum conformal family. The formal forms of these dissimilarity measures and the derived Fisher information metric from contributions of general operators are also given. As an application of the results, we use these dissimilarity measures to compare the excited and thermal states, and examine the eigenstate thermalization hypothesis (ETH) by showing how they behave in high temperature limit. This would help to understand how ETH in 2D CFT can be defined more precisely. We discuss the possibility that all the dissimilarity measures considered here vanish when comparing the reduced density matrices of an excited state and a generalized Gibbs ensemble thermal state. We also discuss ETH for a microcanonical ensemble thermal state in a 2D large central charge CFT, and find that it is approximately satisfied for a small subsystem and violated for a large subsystem.
CFD determination of flow perturbation boundary conditions for seal rotordynamic modeling
NASA Astrophysics Data System (ADS)
Venkatesan, Ganesh
2002-09-01
A new approach has been developed and utilized to determine the flow field perturbations (i.e. disturbance due to rotor eccentricity and/or motion) upstream of and within a non-contacting seal. The results are proposed for use with bulk-flow perturbation and CFD-perturbation seal rotordynamic models, as well as in fully 3-D CFD models, to specify approximate boundary conditions for the first-order variables at the computational domain inlet. The perturbation quantities were evaluated by subtracting the numerical flow field solutions corresponding to the concentric rotor position from that for an eccentric rotor position. The disturbance pressure quantities predicted from the numerical solutions were validated by comparing with previous pressure measurements. A parametric study was performed to understand the influence of upstream chamber height, seal clearance, shaft speed, whirl speed, zeroth-order streamwise and swirl velocities, and downstream pressure on the distribution of the first-order quantities in the upstream chamber, seal inlet and seal exit regions. Radially bulk-averaged first-order quantities were evaluated in the upstream chamber, as well as at the seal inlet and exit. The results were finally presented in the form of generalized dimensionless boundary condition correlations so that they can be applied to seal rotordynamic models over a wide range of operating conditions and geometries. To examine the effect of the proposed, approximate first-order boundary conditions on the solutions of the fully 3-D CFD rotordynamic models, the first-order boundary condition correlations for the upstream chamber were used to adjust the circumferential distribution of domain inlet values. The benefit of the boundary condition expressions was assessed for two previously measured test cases, one for a gas seal and the other for a liquid seal. For the gas seal case, a significant improvement in the prediction of the cross-coupled stiffness, when including the proposed first-order inlet boundary values, was found. In the case of liquid seals the tangential impedance values obtained with boundary condition adjustments showed a very slight improvement for a range of whirl speeds over those obtained without them. The radial impedance values obtained with the new adjustments showed a significant improvement over those obtained without them.
López-Mondéjar, Rubén; Antón, Anabel; Raidl, Stefan; Ros, Margarita; Pascual, José Antonio
2010-04-01
The species of the genus Trichoderma are used successfully as biocontrol agents against a wide range of phytopathogenic fungi. Among them, Trichoderma harzianum is especially effective. However, to develop more effective fungal biocontrol strategies in organic substrates and soil, tools for monitoring the control agents are required. Real-time PCR is potentially an effective tool for the quantification of fungi in environmental samples. The aim of this study consisted of the development and application of a real-time PCR-based method to the quantification of T. harzianum, and the extrapolation of these data to fungal biomass values. A set of primers and a TaqMan probe for the ITS region of the fungal genome were designed and tested, and amplification was correlated to biomass measurements obtained with optical microscopy and image analysis, of the hyphal length of the mycelium of the colony. A correlation of 0.76 between ITS copies and biomass was obtained. The extrapolation of the quantity of ITS copies, calculated based on real-time PCR data, into quantities of fungal biomass provides potentially a more accurate value of the quantity of soil fungi. Copyright 2009 Elsevier Ltd. All rights reserved.
Water requirements of the carbon-black industry
Conklin, Howard L.
1956-01-01
Carbon blacks include an important group of industrial carbons used chiefly as a reinforcing agent in rubber tires. In 1953 more than 1,610 million pounds of carbon black was produced, of which approximately 1,134 million pounds was consumed by the rubber industry. The carbon-black industry uses small quantities of water as compared to some industries; however, the water requirements of the industry are important because of the dependence of the rubber-tire industry on carbon black.Two methods are used in the manufacture of carbon black - contact and furnace. The only process use of water in the contact method is that used in pelleting. Water is used also in the plant washhouse and for cleaning, and sometimes the company camp may be supplied by the plant. A survey made during the last quarter of 1953 showed that the average values of unit water use at contact plants for process use, all plant uses, and all uses including company camps are 0.08, 0.14, and 0.98 gallon of water per pound of carbon black respectively.In addition to use in wet pelleting, large quantities of water are required in continuous and cyclic furnace methods to reduce the temperature of the gases of decomposition in order to separate and collect the entrained carbon black. The 22 furnace plants in operation in 1953 used a total of 12.4 million gallons per day for process use. Four furnace plants generate electric power for plant use; condenser-cooling water for one such plant may nearly equal the requirements of the entire industry for process use. The average values of unit water use at furnace plants for process use, all plant uses and all uses including company camps but excluding power generation are 3.26, 3.34, and 3.45 gallons of water per pound of carbon black respectively.Carbon-black plants in remote, sparsely settled areas often must maintain company camps for employees. Twenty-one of twenty-seven contact plants surveyed in 1953 had company camps. These camps used large quantities of water: 0.84 gallon per pound of carbon black as compared to 0.14 gallon per pound used in the plants.Furnace plants can generally be located near a labor supply and, therefore, do not require company camps. Ten of the twenty-two furnace plants surveyed in 1953 had company camps.Because water used for pelleting and gas quenching is evaporated, leaving the dissolved minerals in the product as objectionable impurities, particular attention was paid to the quality of water available for use at the plants visited during the 1953 survey. Reports of chemical analyses of water samples were obtained at 23 plants. A study of these reports does not develop a pattern of the limits of tolerance of dissolved solids in water used in process or of the need for water treatment based on geographical location of the plant. However these analyses show that water used for quenching contains less dissolved solids than water used by the industry for any other purpose.Based on trends in the industry it is expected that the quantity of water used by the carbon-black industry will increase more rapidly than will the quantity of carbon black produced because of the increasing percentage produced in furnace plants, and that selection of sites for modern furnace plants will be influenced more by quantity and quality of the available water supply than was the case in selecting sites for contact plants for which low-cost natural gas was the primary consideration.
At Birth, Humans Associate "Few" with Left and "Many" with Right.
de Hevia, Maria Dolores; Veggiotti, Ludovica; Streri, Arlette; Bonn, Cory D
2017-12-18
Humans use spatial representations to structure abstract concepts [1]. One of the most well-known examples is the "mental number line"-the propensity to imagine numbers oriented in space [2, 3]. Human infants [4, 5], children [6, 7], adults [8], and nonhuman animals [9, 10] associate small numbers with the left side of space and large numbers with the right. In humans, cultural artifacts, such as the direction of reading and writing, modulate the directionality of this representation, with right-to-left reading cultures associating small numbers with right and large numbers with left [11], whereas the opposite association permeates left-to-right reading cultures [8]. Number-space mapping plays a central role in human mathematical concepts [12], but its origins remain unclear: is it the result of an innate bias or does it develop after birth? Infant humans are passively exposed to a spatially coded environment, so experience and culture could underlie the mental number line. To rule out this possibility, we tested neonates' responses to small or large auditory quantities paired with geometric figures presented on either the left or right sides of the screen. We show that 0- to 3-day-old neonates associate a small quantity with the left and a large quantity with the right when the multidimensional stimulus contains discrete numerical information, providing evidence that representations of number are associated to an oriented space at the start of postnatal life, prior to experience with language, culture, or with culture-specific biases. Copyright © 2017 Elsevier Ltd. All rights reserved.
Electrochemical cell for obtaining oxygen from carbon dioxide atmospheres
NASA Technical Reports Server (NTRS)
Hooker, M. W.; Rast, H. E.; Rogers, D. K.
1989-01-01
For manned missions to Mars to become a reality, an efficient and reliable means of obtaining oxygen from the carbon dioxide-rich atmosphere will be required. Otherwise, the high cost of transporting the oxygen needed to sustain the astronauts will severely restrict the expedition to the martian surface. Recently, the use of electrochemical devices has been explored as a means of obtaining oxygen from the carbon dioxide-rich atmosphere. In these devices, oxygen ions diffuse through solid oxide membranes, thus, separating oxygen from the other gases presented. This phenomenon has only recently been explored as a means of obtaining large quantities of oxygen from toxic atmospheres, although first observed by Walter nernst in 1899. Nernst observed that stabilized zirconia will conduct oxygen ions when an electrical potential is applied across metallic electrodes applied to the ceramic membrane. Diatomic oxygen molecules are dissociated at the positive electrode/electrolyte interface. The oxygen ions enter the ceramic body due to the ion density gradient which is produced by the electrical potential across the electrolytic membrane. Once the ions have diffused through the membrane, they reform diatomic oxygen molecules at the anode. The separation of oxygen from carbon dioxide is achieved by the combination of thermal and electrochemical processes. The thermal decomposition of carbon dioxide (at 1000 C) results in the production of carbon monoxide and oxygen by the reaction.
Past clearing and harvesting of the deciduous hardwood forests of eastern USA released large amount of carbon dioxide into the atmosphere, but through recovery and regrowth these forests are now accumulating atmospheric carbon (C). This study examined quantities and distribution ...
Brunborg, Geir Scott; Østhus, Ståle
2015-02-01
We investigated if increased drinking frequency among adults in the second half of life co-occurred with increased usual quantity and increased intoxication frequency. Two-wave panel study. Norway. Norwegian adults (1017 women and 959 men) aged 40-79 years. Drinking frequency, usual quantity and intoxication frequency was measured by self-report in 2002/03 and again in 2007/08. Information about gender, age and level of education was obtained from the public register. Health was collected by self-report. Because of a significant gender × change in drinking frequency interaction effect on change in intoxication frequency (b = 0.02, P = 0.013), women and men were analysed separately. After adjusting for covariates, women who increase their drinking frequency showed a non-significant decrease in usual quantity [low initial usual quantity (LIUQ): β = -0.01, P = 0.879; high initial usual quantity (HIUQ): β = -0.06, P = 0.164] and a non-significant increase in intoxication frequency (LIUQ: β = 0.04, P = 0.569; HIUQ: β = 0.09, P = 0.251). Men who increased their drinking frequency showed a small decrease in usual quantity (LIUQ: β = -0.06, P = 0.049; HIUQ: β = -0.05, P = 0.002) and a small increase in intoxication frequency (LIUQ: β = 0.05, P = 0.035; HIUQ: β = 0.13, P = 0.004). Among Norwegian adults in the second half of life, increased drinking frequency appears to be associated with a small reduction in usual quantity, and a small increase in frequency of drinking to intoxication. © 2014 Society for the Study of Addiction.
Presidential Green Chemistry Challenge: 2011 Small Business Award
Presidential Green Chemistry Challenge 2011 award winner, BioAmber, developed an integrated technology to produce large, commercial quantities of succinic acid by bacterial fermentation, replacing petroleum-based feedstocks.
Collective synthesis of natural products by means of organocascade catalysis.
Jones, Spencer B; Simmons, Bryon; Mastracchio, Anthony; MacMillan, David W C
2011-07-13
Organic chemists are now able to synthesize small quantities of almost any known natural product, given sufficient time, resources and effort. However, translation of the academic successes in total synthesis to the large-scale construction of complex natural products and the development of large collections of biologically relevant molecules present significant challenges to synthetic chemists. Here we show that the application of two nature-inspired techniques, namely organocascade catalysis and collective natural product synthesis, can facilitate the preparation of useful quantities of a range of structurally diverse natural products from a common molecular scaffold. The power of this concept has been demonstrated through the expedient, asymmetric total syntheses of six well-known alkaloid natural products: strychnine, aspidospermidine, vincadifformine, akuammicine, kopsanone and kopsinine. ©2011 Macmillan Publishers Limited. All rights reserved
Cryptic species of Paracoccidioides brasiliensis: impact on paracoccidioidomycosis immunodiagnosis
Machado, Gabriel Capella; Moris, Daniela Vanessa; Arantes, Thales Domingos; Silva, Luciane Regina Franciscone; Theodoro, Raquel Cordeiro; Mendes, Rinaldo Pôncio; Vicentini, Adriana Pardini; Bagagli, Eduardo
2013-01-01
We aimed to evaluate whether the occurrence of cryptic species of Paracoccidioides brasiliensis, S1, PS2, PS3 and Paracoccidioides lutzii, has implications in the immunodiagnosis of paracoccidioidomycosis (PCM). Small quantities of the antigen gp43 were found in culture filtrates of P. lutzii strains and this molecule appeared to be more variable within P. lutzii because the synonymous-nonsynonymous mutation rate was lower, indicating an evolutionary process different from that of the remaining genotypes. The production of gp43 also varied between isolates belonging to the same species, indicating that speciation events are important, but not sufficient to fully explain the diversity in the production of this antigen. The culture filtrate antigen AgEpm83, which was obtained from a PS3 isolate, showed large quantities of gp43 and reactivity by immunodiffusion assays, similar to the standard antigen (AgB-339) from an S1 isolate. Furthermore, AgEpm83 was capable of serologically differentiating five serum samples from patients from the Botucatu and Jundiaí regions. These patients had confirmed PCM but, were non-reactive to the standard antigen, thus demonstrating an alternative for serological diagnosis in regions in which S1 and PS2 occur. We also emphasise that it is not advisable to use a single antigen preparation to diagnose PCM, a disease that is caused by highly diverse pathogens. PMID:23903981
Brodmann, Paul A; Reyer, H-U; Bollmann, Kurt; Schläpfer, Alex R; Rauter, Claudia
1997-01-01
Studies relating reproduction to food availability are usually restricted to food quantity, but ignore food quality and the effects of habitat structure on obtaining the food. This is particularly true for insectivorous birds. In this study we relate measures of reproductive success, time of reproduction and nestling size of water pipits (Anthus spinoletta) to biomass, taxonomic composition and nutritional content of available food, and to vegetation structure and distance to feeding sites. Clutch size was positively correlated with the proportion of grass at the feeding sites, which facilitates foraging. This suggests that water pipits adapt their clutch size to environmental conditions. Also, pipits started breeding earlier and produced more fledglings when abundant food and a large proportion of grass were available, probably because these conditions allow the birds to gain more energy in less time. The number of fledglings was positively correlated with the energy content of available food. No significant relationships were found between feeding conditions and nestling size or the time that nestlings took to fledge. This suggests that water pipits do not invest more in individual nestlings when food conditions are favourable but rather start breeding earlier and produce more young. Taxonomic composition and nutritional content of prey were not correlated with any of the reproductive parameters, indicating that profitability rather than quality of food affects reproductive success.
[Prokaryotic expression systems].
Porowińska, Dorota; Wujak, Magdalena; Roszek, Katarzyna; Komoszyński, Michał
2013-03-01
For overproduction of recombinant proteins both eukaryotic and prokaryotic expression systems are used. Choosing the right system depends, among other things, on the growth rate and culture of host cells, level of the target gene expression and posttranslational processing of the synthesized protein. Regardless of the type of expression system, its basic elements are the vector and the expression host. The most widely used system for protein overproduction, both on a laboratory and industrial scale, is the prokaryotic system. This system is based primarily on the bacteria E. coli, although increasingly often Bacillus species are used. The prokaryotic system allows one to obtain large quantities of recombinant proteins in a short time. A simple and inexpensive bacterial cell culture and well-known mechanisms of transcription and translation facilitate the use of these microorganisms. The simplicity of genetic modifications and the availability of many bacterial mutants are additional advantages of the prokaryotic system. In this article we characterize the structural elements of prokaryotic expression vectors. Also strategies for preparation of the target protein gene that increase productivity, facilitate detection and purification of recombinant protein and provide its activity are discussed. Bacterial strains often used as host cells in expression systems as well as the potential location of heterologous proteins are characterized. Knowledge of the basic elements of the prokaryotic expression system allows for production of biologically active proteins in a short time and in satisfactory quantities.
Rapid isolation of mycoviral double-stranded RNA from Botrytis cinerea and Saccharomyces cerevisiae.
Castillo, Antonio; Cottet, Luis; Castro, Miguel; Sepúlveda, Felipe
2011-01-25
In most of the infected fungi, the mycoviruses are latent or cryptic, the infected fungus does not show disease symptoms, and it is phenotypically identical to a non-infected strain of the same species. Because of these properties, the initial stage in the search for fungi infected with mycoviruses is the detection of their viral genome, which in most of the described cases corresponds to double-stranded RNA (dsRNA). So to analyze a large number of fungal isolates it is necessary to have a simple and rapid method to detect dsRNA. A rapid method to isolate dsRNA from a virus-infected filamentous fungus, Botrytis cinerea, and from a killer strain of Saccharomyces cerevisiae using commercial minicolumns packed with CF11 cellulose was developed. In addition to being a rapid method, it allows to use small quantities of yeasts or mycelium as starting material, being obtained sufficient dsRNA quantity that can later be analyzed by agarose gel electrophoresis, treated with enzymes for its partial characterization, amplified by RT-PCR and cloned in appropriate vectors for further sequencing. The method yields high quality dsRNA, free from DNA and ssRNA. The use of nucleases to degrade the DNA or the ssRNA is not required, and it can be used to isolate dsRNA from any type of fungi or any biological sample that contains dsRNA.
In vivo MRI Using Laser Polarized Noble Gases.
NASA Astrophysics Data System (ADS)
Cates, G. D.
1996-03-01
A new technique for magnetic resonance imaging (MRI) will be reviewed in which the noble gas nuclei ^3He and ^129Xe are used as the source of signal instead of the protons in water, as is the case in conventional MRI. The noble gas nuclei are polarized by spin exchange with laser optically pumped alkali-metal vapor. The noble gas, which under appropriate conditions can exhibit spin relaxation times of hours to days, can be inhaled, making it possible to obtain images of the gas space of the lungs of unprecedented resolution. In the case of ^129Xe, substantial quantities of gas dissolves into the blood, opening up the prospect of imaging other parts of the body such as the heart and the brain. Recent results will be reviewed, including lung images of both guinea pigs and humans from a Duke/Princeton collaboration, and spectroscopic measurements of ^129Xe that is dissolved in mouse blood, from the Stony Brook group. Other results will be reviewed as available. Attention will be given to the issues involved in producing large quantities of polarized noble gas for imaging, including a discussion of the use of high power diode laser arrays, a technology that has helped this new MRI technique grow quickly to be of potential clinical value. Finally, future prospects for the diagnosis of disease will be discussed.
Shiraki, D.; Commaux, N.; Baylor, L. R.; ...
2016-06-27
Injection of large shattered pellets composed of variable quantities of the main ion species (deuterium) and high-Z impurities (neon) in the DIII-D tokamak demonstrate control of thermal quench (TQ) and current quench (CQ) properties in mitigated disruptions. As the pellet composition is varied, TQ radiation fractions increase continuously with the quantity of radiating impurity in the pellet, with a corresponding decrease in divertor heating. Post-TQ plasma resistivities increase as a result of the higher radiation fraction, allowing control of current decay timescales based on the pellet composition. Magnetic reconstructions during the CQ show that control of the current decay ratemore » allows continuous variation of the minimum safety factor during the vertically unstable disruption, reducing the halo current fraction and resulting vessel displacement. Both TQ and CQ characteristics are observed to saturate at relatively low quantities of neon, indicating that effective mitigation of disruption loads by shattered pellet injection (SPI) can be achieved with modest impurity quantities, within injection quantities anticipated for ITER. In conclusion, this mixed species SPI technique provides apossible approach for tuning disruption properties to remain within the limited ranges allowed in the ITER design.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shiraki, D.; Commaux, N.; Baylor, L. R.
Injection of large shattered pellets composed of variable quantities of the main ion species (deuterium) and high-Z impurities (neon) in the DIII-D tokamak demonstrate control of thermal quench (TQ) and current quench (CQ) properties in mitigated disruptions. As the pellet composition is varied, TQ radiation fractions increase continuously with the quantity of radiating impurity in the pellet, with a corresponding decrease in divertor heating. Post-TQ plasma resistivities increase as a result of the higher radiation fraction, allowing control of current decay timescales based on the pellet composition. Magnetic reconstructions during the CQ show that control of the current decay ratemore » allows continuous variation of the minimum safety factor during the vertically unstable disruption, reducing the halo current fraction and resulting vessel displacement. Both TQ and CQ characteristics are observed to saturate at relatively low quantities of neon, indicating that effective mitigation of disruption loads by shattered pellet injection (SPI) can be achieved with modest impurity quantities, within injection quantities anticipated for ITER. In conclusion, this mixed species SPI technique provides apossible approach for tuning disruption properties to remain within the limited ranges allowed in the ITER design.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Shiraki, D.; Commaux, N.; Baylor, L. R.
Injection of large shattered pellets composed of variable quantities of the main ion species (deuterium) and high-Z impurities (neon) in the DIII-D tokamak demonstrates control of thermal quench (TQ) and current quench (CQ) properties in mitigated disruptions. As the pellet composition is varied, TQ radiation fractions increase continuously with the quantity of radiating impurity in the pellet, with a corresponding decrease in divertor heating. Post-TQ plasma resistivities increase as a result of the higher radiation fraction, allowing control of current decay timescales based on the pellet composition. Magnetic reconstructions during the CQ show that control of the current decay ratemore » allows continuous variation of the minimum safety factor during the vertically unstable disruption, reducing the halo current fraction and resulting vessel displacement. Both TQ and CQ characteristics are observed to saturate at relatively low quantities of neon, indicating that effective mitigation of disruption loads by shattered pellet injection (SPI) can be achieved with modest impurity quantities, within injection quantities anticipated for ITER. This mixed species SPI technique provides a possible approach for tuning disruption properties to remain within the limited ranges allowed in the ITER design.« less
Analytical test results for archived core composite samples from tanks 241-TY-101 and 241-TY-103
DOE Office of Scientific and Technical Information (OSTI.GOV)
Beck, M.A.
1993-07-16
This report describes the analytical tests performed on archived core composite samples form a 1.085 sampling of the 241-TY-101 (101-TY) and 241-TY-103 (103-TY) single shell waste tanks. Both tanks are suspected of containing quantities of ferrocyanide compounds, as a result of process activities in the late 1950`s. Although limited quantities of the composite samples remained, attempts were made to obtain as much analytical information as possible, especially regarding the chemical and thermal properties of the material.
Calabi-Yau Volumes and Reflexive Polytopes
NASA Astrophysics Data System (ADS)
He, Yang-Hui; Seong, Rak-Kyeong; Yau, Shing-Tung
2018-04-01
We study various geometrical quantities for Calabi-Yau varieties realized as cones over Gorenstein Fano varieties, obtained as toric varieties from reflexive polytopes in various dimensions. Focus is made on reflexive polytopes up to dimension 4 and the minimized volumes of the Sasaki-Einstein base of the corresponding Calabi-Yau cone are calculated. By doing so, we conjecture new bounds for the Sasaki-Einstein volume with respect to various topological quantities of the corresponding toric varieties. We give interpretations about these volume bounds in the context of associated field theories via the AdS/CFT correspondence.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Reyne, G.; Magnin, H.; Berliat, G.
A supervisor has been developed so as to allow successive 3D computations of different quantities by different softwares on the same physical problem. Noise of a given power oil transformer can be deduced from the surface vibrations of the tank. These vibrations are obtained through a mechanic computation whose Inputs are the electromagnetic forces provided . by an electromagnetic computation. Magnetic, mechanic and acoustic experimental data are compared with the results of the 3D computations. Stress Is put on the main characteristics of the supervisor such as the transfer of a given quantity from one mesh to the other.
Hamiltonization of Solids of Revolution Through Reduction
NASA Astrophysics Data System (ADS)
Balseiro, Paula
2017-12-01
In this paper, we study the relation between conserved quantities of nonholonomic systems and the hamiltonization problem employing the geometric methods of Balseiro (Arch Ration Mech Anal 214:453-501, 2014) and Balseiro and Garcia-Naranjo (Arch Ration Mech Anal 205(1):267-310, 2012). We illustrate the theory with classical examples describing the dynamics of solids of revolution rolling without sliding on a plane. In these cases, using the existence of two conserved quantities we obtain, by means of gauge transformations and symmetry reduction, genuine Poisson brackets describing the reduced dynamics.
Sensitive method to monitor trace quantities of benzanthrone in workers of dyestuff industries
DOE Office of Scientific and Technical Information (OSTI.GOV)
Joshi, A.; Khanna, S.K.; Singh, G.B.
1986-03-01
Dyestuff workers coming in contact with benzanthrone (an intermediate used for the synthesis of a variety of dyes) develop skin lesions, gastritis, liver malfunctions, and sexual disturbances. A highly sensitive fluorometric method to monitor trace quantities of benzanthrone in urine, serum, and biological tissues for experimental studies, has been developed. Coupled with simple extraction and resolution, optimum fluorescence is obtained in an equal mixture of chloroform:methanol, detecting as low as 2 ng benzanthrone. This method is approximately 250 times more sensitive than currently available colorimetric assay.
Numerical Simulation of a Spatially Evolving Supersonic Turbulent Boundary Layer
NASA Technical Reports Server (NTRS)
Gatski, T. B.; Erlebacher, G.
2002-01-01
The results from direct numerical simulations of a spatially evolving, supersonic, flat-plate turbulent boundary-layer flow, with free-stream Mach number of 2.25 are presented. The simulated flow field extends from a transition region, initiated by wall suction and blowing near the inflow boundary, into the fully turbulent regime. Distributions of mean and turbulent flow quantities are obtained and an analysis of these quantities is performed at a downstream station corresponding to Re(sub x)= 5.548 x10(exp 6) based on distance from the leading edge.
NASA Astrophysics Data System (ADS)
Lotfy, Kh.
2018-05-01
In this article, theoretical discussions for a novel mathematical-physical Photothermal diffusion (PTD) model in the generalized thermoelasticity theory with photothermal processes and chemical action are introduced. The mean idea of this model depends on the interaction between quasi-particles (plasma waves) that depends on the kind of the used materials, the mechanical forces acting on the surface, the generalized thermo and mass diffusion (due to coupling of temperature fields with thermal waves and chemical potential) and the elastic waves. The one dimensional Laplace transforms is used to obtain the exact solution for some physical and chemical quantities for a thin circular plate of a semiconducting polymer nanocomposite such as silicon (Si). New variables are deduced and discussed. The obtained results of the physical quantities are presented analytically and illustrated graphically with some important applications.
NASA Astrophysics Data System (ADS)
Sibley, David; Nold, Andreas; Kalliadasis, Serafim
2015-11-01
Density Functional Theory (DFT), a statistical mechanics of fluids approach, captures microscopic details of the fluid density structure in the vicinity of contact lines, as seen in computations in our recent study. Contact lines describe the location where interfaces between two fluids meet solid substrates, and have stimulated a wealth of research due to both their ubiquity in nature and technological applications and also due to their rich multiscale behaviour. Whilst progress can be made computationally to capture the microscopic to mesoscopic structure from DFT, complete analytical results to fully bridge to the macroscale are lacking. In this work, we describe our efforts to bring asymptotic methods to DFT to obtain results for contact angles and other macroscopic quantities in various parameter regimes. We acknowledge financial support from European Research Council via Advanced Grant No. 247031.
Real-time and imaginary-time quantum hierarchal Fokker-Planck equations
NASA Astrophysics Data System (ADS)
Tanimura, Yoshitaka
2015-04-01
We consider a quantum mechanical system represented in phase space (referred to hereafter as "Wigner space"), coupled to a harmonic oscillator bath. We derive quantum hierarchal Fokker-Planck (QHFP) equations not only in real time but also in imaginary time, which represents an inverse temperature. This is an extension of a previous work, in which we studied a spin-boson system, to a Brownian system. It is shown that the QHFP in real time obtained from a correlated thermal equilibrium state of the total system possesses the same form as those obtained from a factorized initial state. A modified terminator for the hierarchal equations of motion is introduced to treat the non-Markovian case more efficiently. Using the imaginary-time QHFP, numerous thermodynamic quantities, including the free energy, entropy, internal energy, heat capacity, and susceptibility, can be evaluated for any potential. These equations allow us to treat non-Markovian, non-perturbative system-bath interactions at finite temperature. Through numerical integration of the real-time QHFP for a harmonic system, we obtain the equilibrium distributions, the auto-correlation function, and the first- and second-order response functions. These results are compared with analytically exact results for the same quantities. This provides a critical test of the formalism for a non-factorized thermal state and elucidates the roles of fluctuation, dissipation, non-Markovian effects, and system-bath coherence. Employing numerical solutions of the imaginary-time QHFP, we demonstrate the capability of this method to obtain thermodynamic quantities for any potential surface. It is shown that both types of QHFP equations can produce numerical results of any desired accuracy. The FORTRAN source codes that we developed, which allow for the treatment of Wigner space dynamics with any potential form (TanimuranFP15 and ImTanimuranFP15), are provided as the supplementary material.
Jia, Jia; Wang, Lili; Gao, Dong; Geng, Xindu
2010-06-01
Flt3 ligand (FL) is a class of cytokines with the functions of promoting early hematopoiesis. It has important clinical value in promoting growth and development of hematopoietic cells and hematopoietic mobilization. In order to obtain large quantities of recombinant human FL (rhFL) by genetic engineering methods for clinic and research, in this work, rhFL was expressed in E. coli as inclusion bodies. The inclusion bodies were recovered, cleaned and solubilized in 8 mol/L urea, the solubilized rhFL was renatured by high performance hydrophobic interaction chromatography (HPHIC) with simultaneous purification, the retention feature and renaturation regularity were studied. The results showed that when the denatured protein concentration was 8.51 g/L, and the end group of stationary phase was PEG800, under the conditions of mobile phase of pH 7.0 and with the addition of 4 mol/L urea, 1.8 mmol/L glutathione (GSH) and 0.3 mmol/L oxidative glutathione (GSSG), a mass recovery of 36.9% and a purity of 94.5% were obtained after refolding with simultaneous purification. The obtained rhFL was successfully renatured with simultaneous purification in only one step of HPHIC, and it provided a foundation for the manufacturing of high quality rhFL.
Scalar and tensor perturbations in loop quantum cosmology: high-order corrections
DOE Office of Scientific and Technical Information (OSTI.GOV)
Zhu, Tao; Wang, Anzhong; Wu, Qiang
2015-10-01
Loop quantum cosmology (LQC) provides promising resolutions to the trans-Planckian issue and initial singularity arising in the inflationary models of general relativity. In general, due to different quantization approaches, LQC involves two types of quantum corrections, the holonomy and inverse-volume, to both of the cosmological background evolution and perturbations. In this paper, using the third-order uniform asymptotic approximations, we derive explicitly the observational quantities of the slow-roll inflation in the framework of LQC with these quantum corrections. We calculate the power spectra, spectral indices, and running of the spectral indices for both scalar and tensor perturbations, whereby the tensor-to-scalar ratiomore » is obtained. We expand all the observables at the time when the inflationary mode crosses the Hubble horizon. As the upper error bounds for the uniform asymptotic approximation at the third-order are ∼< 0.15%, these results represent the most accurate results obtained so far in the literature. It is also shown that with the inverse-volume corrections, both scalar and tensor spectra exhibit a deviation from the usual shape at large scales. Then, using the Planck, BAO and SN data we obtain new constraints on quantum gravitational effects from LQC corrections, and find that such effects could be within the detection of the forthcoming experiments.« less
Low-energy ion irradiation in HiPIMS to enable anatase TiO2 selective growth
NASA Astrophysics Data System (ADS)
Cemin, Felipe; Tsukamoto, Makoto; Keraudy, Julien; Antunes, Vinícius Gabriel; Helmersson, Ulf; Alvarez, Fernando; Minea, Tiberiu; Lundin, Daniel
2018-06-01
High power impulse magnetron sputtering (HiPIMS) has already demonstrated great potential for synthesizing the high-energy crystalline phase of titanium dioxide (rutile TiO2) due to large quantities of highly energetic ions present in the discharge. In this work, it is shown that the metastable anatase phase can also be obtained by HiPIMS. The required deposition conditions have been identified by systematically studying the phase formation, microstructure and chemical composition as a function of mode of target operation as well as of substrate temperature, working pressure, and peak current density. It is found that films deposited in the metal and transition modes are predominantly amorphous and contain substoichiometric TiO x compounds, while in compound mode they are well-crystallized and present only O2‑ ions bound to Ti4+, i.e. pure TiO2. Anatase TiO2 films are obtained for working pressures between 1 and 2 Pa, a peak current density of ~1 A cm‑2 and deposition temperatures lower than 300 °C. Rutile is favored at lower pressures (<1 Pa) and higher peak current densities (>2 A cm‑2), while amorphous films are obtained at higher pressures (5 Pa). Microstructural characterization of selected films is also presented.
Vibrations of a Mindlin plate subjected to a pair of inertial loads moving in opposite directions
NASA Astrophysics Data System (ADS)
Dyniewicz, Bartłomiej; Pisarski, Dominik; Bajer, Czesław I.
2017-01-01
A Mindlin plate subjected to a pair of inertial loads traveling at a constant high speed in opposite directions along arbitrary trajectory, straight or curved, is presented. The masses represent vehicles passing a bridge or track plates. A numerical solution is obtained using the space-time finite element method, since it allows a clear and simple derivation of the characteristic matrices of the time-stepping procedure. The transition from one spatial finite element to another must be energetically consistent. In the case of the moving inertial load the classical time-integration schemes are methodologically difficult, since we consider the Dirac delta term with a moving argument. The proposed numerical approach provides the correct definition of force equilibrium in the time interval. The given approach closes the problem of the numerical analysis of vibration of a structure subjected to inertial loads moving arbitrarily with acceleration. The results obtained for a massless and an inertial load traveling over a Mindlin plate at various speeds are compared with benchmark results obtained for a Kirchhoff plate. The pair of inertial forces traveling in opposite directions causes displacements and stresses more than twice as large as their corresponding quantities observed for the passage of a single mass.
Automation of large scale transient protein expression in mammalian cells
Zhao, Yuguang; Bishop, Benjamin; Clay, Jordan E.; Lu, Weixian; Jones, Margaret; Daenke, Susan; Siebold, Christian; Stuart, David I.; Yvonne Jones, E.; Radu Aricescu, A.
2011-01-01
Traditional mammalian expression systems rely on the time-consuming generation of stable cell lines; this is difficult to accommodate within a modern structural biology pipeline. Transient transfections are a fast, cost-effective solution, but require skilled cell culture scientists, making man-power a limiting factor in a setting where numerous samples are processed in parallel. Here we report a strategy employing a customised CompacT SelecT cell culture robot allowing the large-scale expression of multiple protein constructs in a transient format. Successful protocols have been designed for automated transient transfection of human embryonic kidney (HEK) 293T and 293S GnTI− cells in various flask formats. Protein yields obtained by this method were similar to those produced manually, with the added benefit of reproducibility, regardless of user. Automation of cell maintenance and transient transfection allows the expression of high quality recombinant protein in a completely sterile environment with limited support from a cell culture scientist. The reduction in human input has the added benefit of enabling continuous cell maintenance and protein production, features of particular importance to structural biology laboratories, which typically use large quantities of pure recombinant proteins, and often require rapid characterisation of a series of modified constructs. This automated method for large scale transient transfection is now offered as a Europe-wide service via the P-cube initiative. PMID:21571074
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ubeda, Carlos, E-mail: cubeda@uta.cl; Miranda, Patricia; Vano, Eliseo
Purpose: To present the results of a patient dose evaluation program in pediatric cardiology and propose local diagnostic reference levels (DRLs) for different types of procedure and age range, in addition to suggesting approaches to correlate patient dose values with patient weight. This study was the first conducted in Latin America for pediatric interventional cardiology under the auspices of the International Atomic Energy Agency. Methods: Over three years, the following data regarding demographic and patient dose values were collected: age, gender, weight, height, number of cine series, total number of cine frames, fluoroscopy time (FT), and two dosimetric quantities, dose-areamore » product (DAP) and cumulative dose (CD), at the patient entrance reference point. The third quartile values for FT, DAP, CD, number of cine series, and the DAP/body weight ratio were proposed as the set of quantities to use as local DRLs. Results: Five hundred and seventeen patients were divided into four age groups. Sample sizes by age group were 120 for <1 yr; 213 for 1 to <5 yr; 82 for 5 to <10 yr; and 102 for 10 to <16 yr. The third quartile values obtained for DAP by diagnostic and therapeutic procedures and age range were 1.17 and 1.11 Gy cm{sup 2} for <1 yr; 1.74 and 1.90 Gy cm{sup 2} for 1 to <5 yr; 2.83 and 3.22 Gy cm{sup 2} for 5 to <10 yr; and 7.34 and 8.68 Gy cm{sup 2} for 10 to <16 yr, respectively. The third quartile value obtained for the DAP/body weight ratio for the full sample of procedures was 0.17 (Gy cm{sup 2}/kg) for diagnostic and therapeutic procedures. Conclusions: The data presented in this paper are an initial attempt at establishing local DRLs in pediatric interventional cardiology, from a large sample of procedures for the standard age bands used in Europe, complemented with the values of the ratio between DAP and patient weight. This permits a rough estimate of DRLs for different patient weights and the refining of these values for the age bands when there may be large differences in child size. These DRLs were obtained at the largest pediatric hospital in Chile, with an active optimization program, and could be used by other hospitals in the Latin America region to compare their current patient dose values and determine whether corrective action is appropriate.« less
Ubeda, Carlos; Miranda, Patricia; Vano, Eliseo
2015-02-01
To present the results of a patient dose evaluation program in pediatric cardiology and propose local diagnostic reference levels (DRLs) for different types of procedure and age range, in addition to suggesting approaches to correlate patient dose values with patient weight. This study was the first conducted in Latin America for pediatric interventional cardiology under the auspices of the International Atomic Energy Agency. Over three years, the following data regarding demographic and patient dose values were collected: age, gender, weight, height, number of cine series, total number of cine frames, fluoroscopy time (FT), and two dosimetric quantities, dose-area product (DAP) and cumulative dose (CD), at the patient entrance reference point. The third quartile values for FT, DAP, CD, number of cine series, and the DAP/body weight ratio were proposed as the set of quantities to use as local DRLs. Five hundred and seventeen patients were divided into four age groups. Sample sizes by age group were 120 for <1 yr; 213 for 1 to <5 yr; 82 for 5 to <10 yr; and 102 for 10 to <16 yr. The third quartile values obtained for DAP by diagnostic and therapeutic procedures and age range were 1.17 and 1.11 Gy cm 2 for <1 yr; 1.74 and 1.90 Gy cm 2 for 1 to <5 yr; 2.83 and 3.22 Gy cm 2 for 5 to <10 yr; and 7.34 and 8.68 Gy cm 2 for 10 to <16 yr, respectively. The third quartile value obtained for the DAP/body weight ratio for the full sample of procedures was 0.17 (Gy cm 2 /kg) for diagnostic and therapeutic procedures. The data presented in this paper are an initial attempt at establishing local DRLs in pediatric interventional cardiology, from a large sample of procedures for the standard age bands used in Europe, complemented with the values of the ratio between DAP and patient weight. This permits a rough estimate of DRLs for different patient weights and the refining of these values for the age bands when there may be large differences in child size. These DRLs were obtained at the largest pediatric hospital in Chile, with an active optimization program, and could be used by other hospitals in the Latin America region to compare their current patient dose values and determine whether corrective action is appropriate. © 2015 American Association of Physicists in Medicine.
Development of Large-Eddy Interaction Model for inhomogeneous turbulent flows
NASA Technical Reports Server (NTRS)
Hong, S. K.; Payne, F. R.
1987-01-01
The objective of this paper is to demonstrate the applicability of a currently proposed model, with minimum empiricism, for calculation of the Reynolds stresses and other turbulence structural quantities in a channel. The current Large-Eddy Interaction Model not only yields Reynolds stresses but also presents an opportunity to illuminate typical characteristic motions of large-scale turbulence and the phenomenological aspects of engineering models for two Reynolds numbers.
Remakus, Sanda; Ma, Xueying; Tang, Lingjuan; Xu, Ren-Huan; Knudson, Cory; Melo-Silva, Carolina R; Rubio, Daniel; Kuo, Yin-Ming; Andrews, Andrew; Sigal, Luis J
2018-05-15
Numerous attempts to produce antiviral vaccines by harnessing memory CD8 T cells have failed. A barrier to progress is that we do not know what makes an Ag a viable target of protective CD8 T cell memory. We found that in mice susceptible to lethal mousepox (the mouse homolog of human smallpox), a dendritic cell vaccine that induced memory CD8 T cells fully protected mice when the infecting virus produced Ag in large quantities and with rapid kinetics. Protection did not occur when the Ag was produced in low amounts, even with rapid kinetics, and protection was only partial when the Ag was produced in large quantities but with slow kinetics. Hence, the amount and timing of Ag expression appear to be key determinants of memory CD8 T cell antiviral protective immunity. These findings may have important implications for vaccine design. Copyright © 2018 by The American Association of Immunologists, Inc.
Glacial melting: an overlooked threat to Antarctic krill.
Fuentes, Verónica; Alurralde, Gastón; Meyer, Bettina; Aguirre, Gastón E; Canepa, Antonio; Wölfl, Anne-Cathrin; Hass, H Christian; Williams, Gabriela N; Schloss, Irene R
2016-06-02
Strandings of marine animals are relatively common in marine systems. However, the underlying mechanisms are poorly understood. We observed mass strandings of krill in Antarctica that appeared to be linked to the presence of glacial meltwater. Climate-induced glacial meltwater leads to an increased occurrence of suspended particles in the sea, which is known to affect the physiology of aquatic organisms. Here, we study the effect of suspended inorganic particles on krill in relation to krill mortality events observed in Potter Cove, Antarctica, between 2003 and 2012. The experimental results showed that large quantities of lithogenic particles affected krill feeding, absorption capacity and performance after only 24 h of exposure. Negative effects were related to both the threshold concentrations and the size of the suspended particles. Analysis of the stomach contents of stranded krill showed large quantities of large particles ( > 10(6 )μm(3)), which were most likely mobilized by glacial meltwater. Ongoing climate-induced glacial melting may impact the coastal ecosystems of Antarctica that rely on krill.
Glacial melting: an overlooked threat to Antarctic krill
Fuentes, Verónica; Alurralde, Gastón; Meyer, Bettina; Aguirre, Gastón E.; Canepa, Antonio; Wölfl, Anne-Cathrin; Hass, H. Christian; Williams, Gabriela N.; Schloss, Irene R.
2016-01-01
Strandings of marine animals are relatively common in marine systems. However, the underlying mechanisms are poorly understood. We observed mass strandings of krill in Antarctica that appeared to be linked to the presence of glacial meltwater. Climate-induced glacial meltwater leads to an increased occurrence of suspended particles in the sea, which is known to affect the physiology of aquatic organisms. Here, we study the effect of suspended inorganic particles on krill in relation to krill mortality events observed in Potter Cove, Antarctica, between 2003 and 2012. The experimental results showed that large quantities of lithogenic particles affected krill feeding, absorption capacity and performance after only 24 h of exposure. Negative effects were related to both the threshold concentrations and the size of the suspended particles. Analysis of the stomach contents of stranded krill showed large quantities of large particles ( > 106 μm3), which were most likely mobilized by glacial meltwater. Ongoing climate-induced glacial melting may impact the coastal ecosystems of Antarctica that rely on krill. PMID:27250339
Development of marijuana and tobacco detectors using potassium-40 gamma-ray emissions
NASA Astrophysics Data System (ADS)
Kirby, John A.; Lindquist, Roy P.
1994-10-01
Measurements were made at the Otay Mesa, CA, border crossing between November 30 and December 4, 1992, to demonstrate proof of concept and the practicality of using potassium 40 (K40) gamma emissions to detect the presence of marijuana in vehicles. Lawrence Livermore National Laboratory personnel, with the assistance of the EPA, set up three large volume gamma ray detectors with lead brick shielding and collimation under a stationary trailer and pickup truck. Measurements were performed for various positions and quantities of marijuana. Also, small quantities of marijuana, cigarettes, and other materials were subjected to gamma counting measurements under controlled geometry conditions to determine their K40 concentration. Larger quantities of heroin and cocaine were subjected to undefined geometry gamma counts for significant K40 gamma emissions.
Set size and culture influence children's attention to number.
Cantrell, Lisa; Kuwabara, Megumi; Smith, Linda B
2015-03-01
Much research evidences a system in adults and young children for approximately representing quantity. Here we provide evidence that the bias to attend to discrete quantity versus other dimensions may be mediated by set size and culture. Preschool-age English-speaking children in the United States and Japanese-speaking children in Japan were tested in a match-to-sample task where number was pitted against cumulative surface area in both large and small numerical set comparisons. Results showed that children from both cultures were biased to attend to the number of items for small sets. Large set responses also showed a general attention to number when ratio difficulty was easy. However, relative to the responses for small sets, attention to number decreased for both groups; moreover, both U.S. and Japanese children showed a significant bias to attend to total amount for difficult numerical ratio distances, although Japanese children shifted attention to total area at relatively smaller set sizes than U.S. children. These results add to our growing understanding of how quantity is represented and how such representation is influenced by context--both cultural and perceptual. Copyright © 2014 Elsevier Inc. All rights reserved.
Haeckel, Rainer; Wosniok, Werner
2010-10-01
The distribution of many quantities in laboratory medicine are considered to be Gaussian if they are symmetric, although, theoretically, a Gaussian distribution is not plausible for quantities that can attain only non-negative values. If a distribution is skewed, further specification of the type is required, which may be difficult to provide. Skewed (non-Gaussian) distributions found in clinical chemistry usually show only moderately large positive skewness (e.g., log-normal- and χ(2) distribution). The degree of skewness depends on the magnitude of the empirical biological variation (CV(e)), as demonstrated using the log-normal distribution. A Gaussian distribution with a small CV(e) (e.g., for plasma sodium) is very similar to a log-normal distribution with the same CV(e). In contrast, a relatively large CV(e) (e.g., plasma aspartate aminotransferase) leads to distinct differences between a Gaussian and a log-normal distribution. If the type of an empirical distribution is unknown, it is proposed that a log-normal distribution be assumed in such cases. This avoids distributional assumptions that are not plausible and does not contradict the observation that distributions with small biological variation look very similar to a Gaussian distribution.
Yeom, Dong Woo; Chae, Bo Ram; Son, Ho Yong; Kim, Jin Han; Chae, Jun Soo; Song, Seh Hyon; Oh, Dongho; Choi, Young Wook
2017-01-01
A novel, supersaturable self-microemulsifying drug delivery system (S-SMEDDS) was successfully formulated to enhance the dissolution and oral absorption of valsartan (VST), a poorly water-soluble drug, while reducing the total quantity for administration. Poloxamer 407 is a selectable, supersaturating agent for VST-containing SMEDDS composed of 10% Capmul ® MCM, 45% Tween ® 20, and 45% Transcutol ® P. The amounts of SMEDDS and Poloxamer 407 were chosen as formulation variables for a 3-level factorial design. Further optimization was established by weighting different levels of importance on response variables for dissolution and total quantity, resulting in an optimal S-SMEDDS in large quantity (S-SMEDDS_LQ; 352 mg in total) and S-SMEDDS in reduced quantity (S-SMEDDS_RQ; 144.6 mg in total). Good agreement was observed between predicted and experimental values for response variables. Consequently, compared with VST powder or suspension and SMEDDS, both S-SMEDDS_LQ and S-SMEDDS_RQ showed excellent in vitro dissolution and in vivo oral bioavailability in rats. The magnitude of dissolution and absorption-enhancing capacities using quantity-based comparisons was in the order S-SMEDDS_RQ > S-SMEDDS_LQ > SMEDDS > VST powder or suspension. Thus, we concluded that, in terms of developing an effective SMEDDS preparation with minimal total quantity, S-SMEDDS_RQ is a promising candidate.
Structure and interactions of fully hydrated dioleoylphosphatidylcholine bilayers.
Tristram-Nagle, S; Petrache, H I; Nagle, J F
1998-01-01
This study focuses on dioleoylphosphatidylcholine (DOPC) bilayers near full hydration. Volumetric data and high-resolution synchrotron x-ray data are used in a method that compares DOPC with well determined gel phase dipalmitoylphosphatidylcholine (DPPC). The key structural quantity obtained is fully hydrated area/lipid A0 = 72.2 +/- 1.1 A2 at 30 degrees C, from which other quantities such as thickness of the bilayer are obtained. Data for samples over osmotic pressures from 0 to 56 atmospheres give an estimate for the area compressibility of KA = 188 dyn/cm. Obtaining the continuous scattering transform and electron density profiles requires correction for liquid crystal fluctuations. Quantitation of these fluctuations opens an experimental window on the fluctuation pressure, the primary repulsive interaction near full hydration. The fluctuation pressure decays exponentially with water spacing, in agreement with analytical results for soft confinement. However, the ratio of decay length lambda(fl) = 5.8 A to hydration pressure decay length lambda = 2.2 A is significantly larger than the value of 2 predicted by analytical theory and close to the ratio obtained in recent simulations. We also obtain the traditional osmotic pressure versus water spacing data. Our analysis of these data shows that estimates of the Hamaker parameter H and the bending modulus Kc are strongly coupled. PMID:9675192
Zhang, Hongcai; Yun, Sanyue; Song, Lingling; Zhang, Yiwen; Zhao, Yanyun
2017-03-01
The crustacean shells of crabs and shrimps produces quantities of by-products, leading to seriously environmental pollution and human health problems during industrial processing, yet they turned into high-value useful products, such as chitin and chitosan. To prepare them under large-scale submerged fermentation level, shrimp shell powders (SSPs) was fermented by successive three-step fermentation of Serratia marcescens B742, Lactobacillus plantarum ATCC 8014 and Rhizopus japonicus M193 to extract chitin and chitosan based on previously optimal conditions. Moreover, the key parameters was investigated to monitor the changes of resulted products during fermentation process. The results showed that the yield of prepared chitin and chitosan reached 21.35 and 13.11% with the recovery rate of 74.67 and 63.42%, respectively. The degree of deacetylation (DDA) and molecular mass (MM) of produced chitosan were 81.23% and 512.06kDa, respectively. The obtained chitin and chitosan was characterized using Fourier transform infrared spectrometer (FT-IR) and X-ray diffraction (XRD) analysis. The established microbial fermentation method can be applied for the industrial large-scale production of chitin and chitosan, while the use of chemical reagents was significantly reduced. Copyright © 2016 Elsevier B.V. All rights reserved.
NASA Astrophysics Data System (ADS)
Zhang, Haina; Li, Decai; Wang, Qinglei; Zhang, Zhili
2013-07-01
The existing researches of the magnetic liquid rotation seal have been mainly oriented to the seal at normal temperature and the seal with the smaller shaft diameter less than 100 mm. However, the large-diameter magnetic liquid rotation seal at low temperature has not been reported both in theory and in application up to now. A key factor restricting the application of the large-diameter magnetic liquid rotation seal at low temperature is the high breakaway torque. In this paper, the factors that influence the breakaway torque including the number of seal stages, the injected quantity of magnetic liquid and the standing time at normal temperature are studied. Two kinds of magnetic liquid with variable content of large particles are prepared first, and a seal feedthrough with 140 mm shaft diameter is used in the experiments. All experiments are carried out in a low temperature chamber with a temperature range from 200°C to -100°C. Different numbers of seal stages are tested under the same condition to study the relation between the breakaway torque and the number of seal stages. Variable quantity of magnetic liquid is injected in the seal gap to get the relation curve of the breakaway torque and the injecting quantity of magnetic liquid. In the experiment for studying the relation between the breakaway torque and the standing time at the normal temperature, the seal feedtrough is laid at normal temperature for different period of time before it is put in the low temperature chamber. The experimental results show that the breakaway torque is proportional to the number of seal stages, the injected quantity of magnetic liquid and the standing time at the normal temperature. Meanwhile, the experimental results are analyzed and the torque formula of magnetic liquid rotation seal at low temperature is deduced from the Navier-Stokes equation on the base of the model of magnetic liquid rotation seal. The presented research can make wider application of the magnetic liquid seal in general. And the large-diameter magnetic liquid rotation seal at low temperature designed by using present research results are to be used in some special fields, such as the military field, etc.
A Improved Seabed Surface Sand Sampling Device
NASA Astrophysics Data System (ADS)
Luo, X.
2017-12-01
In marine geology research it is necessary to obtain a suf fcient quantity of seabed surface samples, while also en- suring that the samples are in their original state. Currently,there are a number of seabed surface sampling devices available, but we fnd it is very diffcult to obtain sand samples using these devices, particularly when dealing with fne sand. Machine-controlled seabed surface sampling devices are also available, but generally unable to dive into deeper regions of water. To obtain larger quantities of seabed surface sand samples in their original states, many researchers have tried to improve upon sampling devices,but these efforts have generally produced ambiguous results, in our opinion.To resolve this issue, we have designed an improved andhighly effective seabed surface sand sampling device that incorporates the strengths of a variety of sampling devices. It is capable of diving into deepwater to obtain fne sand samples and is also suited for use in streams, rivers, lakes and seas with varying levels of depth (up to 100 m). This device can be used for geological mapping, underwater prospecting, geological engineering and ecological, environmental studies in both marine and terrestrial waters.
Estimating combustion of large downed woody debris from residual white ash
Alistair M. S. Smith; Andrew T. Hudak
2005-01-01
The production of residual white ash patches within wildfires represents near-complete combustion of the available fuel and releases a considerable quantity of gases to the atmosphere. These patches are generally produced from combustion of large downed woody debris (LDWD) such as fallen trees and snags. However, LDWD are generally ignored in calculations of fuel...
Code of Federal Regulations, 2014 CFR
2014-01-01
... INSPECTION Standards Official Standard Grades for Dark Air-Cured Tobacco (u.s. Types 35, 36, 37 and Foreign... separated by sorting; (b) Tobacco which contains an abnormally large quantity of foreign matter or an...
Code of Federal Regulations, 2013 CFR
2013-01-01
... INSPECTION Standards Official Standard Grades for Dark Air-Cured Tobacco (u.s. Types 35, 36, 37 and Foreign... separated by sorting; (b) Tobacco which contains an abnormally large quantity of foreign matter or an...
Code of Federal Regulations, 2012 CFR
2012-01-01
... INSPECTION Standards Official Standard Grades for Dark Air-Cured Tobacco (u.s. Types 35, 36, 37 and Foreign... separated by sorting; (b) Tobacco which contains an abnormally large quantity of foreign matter or an...
Ghorbani Moghaddam, Masoud; Achuthan, Ajit; Bednarcyk, Brett A; Arnold, Steven M; Pineda, Evan J
2016-05-04
A multiscale computational model is developed for determining the elasto-plastic behavior of polycrystal metals by employing a single crystal plasticity constitutive model that can capture the microstructural scale stress field on a finite element analysis (FEA) framework. The generalized method of cells (GMC) micromechanics model is used for homogenizing the local field quantities. At first, the stand-alone GMC is applied for studying simple material microstructures such as a repeating unit cell (RUC) containing single grain or two grains under uniaxial loading conditions. For verification, the results obtained by the stand-alone GMC are compared to those from an analogous FEA model incorporating the same single crystal plasticity constitutive model. This verification is then extended to samples containing tens to hundreds of grains. The results demonstrate that the GMC homogenization combined with the crystal plasticity constitutive framework is a promising approach for failure analysis of structures as it allows for properly predicting the von Mises stress in the entire RUC, in an average sense, as well as in the local microstructural level, i.e. , each individual grain. Two-three orders of saving in computational cost, at the expense of some accuracy in prediction, especially in the prediction of the components of local tensor field quantities and the quantities near the grain boundaries, was obtained with GMC. Finally, the capability of the developed multiscale model linking FEA and GMC to solve real-life-sized structures is demonstrated by successfully analyzing an engine disc component and determining the microstructural scale details of the field quantities.
Age-dependent biochemical quantities: an approach for calculating reference intervals.
Bjerner, J
2007-01-01
A parametric method is often preferred when calculating reference intervals for biochemical quantities, as non-parametric methods are less efficient and require more observations/study subjects. Parametric methods are complicated, however, because of three commonly encountered features. First, biochemical quantities seldom display a Gaussian distribution, and there must either be a transformation procedure to obtain such a distribution or a more complex distribution has to be used. Second, biochemical quantities are often dependent on a continuous covariate, exemplified by rising serum concentrations of MUC1 (episialin, CA15.3) with increasing age. Third, outliers often exert substantial influence on parametric estimations and therefore need to be excluded before calculations are made. The International Federation of Clinical Chemistry (IFCC) currently recommends that confidence intervals be calculated for the reference centiles obtained. However, common statistical packages allowing for the adjustment of a continuous covariate do not make this calculation. In the method described in the current study, Tukey's fence is used to eliminate outliers and two-stage transformations (modulus-exponential-normal) in order to render Gaussian distributions. Fractional polynomials are employed to model functions for mean and standard deviations dependent on a covariate, and the model is selected by maximum likelihood. Confidence intervals are calculated for the fitted centiles by combining parameter estimation and sampling uncertainties. Finally, the elimination of outliers was made dependent on covariates by reiteration. Though a good knowledge of statistical theory is needed when performing the analysis, the current method is rewarding because the results are of practical use in patient care.
Ghorbani Moghaddam, Masoud; Achuthan, Ajit; Bednarcyk, Brett A.; Arnold, Steven M.; Pineda, Evan J.
2016-01-01
A multiscale computational model is developed for determining the elasto-plastic behavior of polycrystal metals by employing a single crystal plasticity constitutive model that can capture the microstructural scale stress field on a finite element analysis (FEA) framework. The generalized method of cells (GMC) micromechanics model is used for homogenizing the local field quantities. At first, the stand-alone GMC is applied for studying simple material microstructures such as a repeating unit cell (RUC) containing single grain or two grains under uniaxial loading conditions. For verification, the results obtained by the stand-alone GMC are compared to those from an analogous FEA model incorporating the same single crystal plasticity constitutive model. This verification is then extended to samples containing tens to hundreds of grains. The results demonstrate that the GMC homogenization combined with the crystal plasticity constitutive framework is a promising approach for failure analysis of structures as it allows for properly predicting the von Mises stress in the entire RUC, in an average sense, as well as in the local microstructural level, i.e., each individual grain. Two–three orders of saving in computational cost, at the expense of some accuracy in prediction, especially in the prediction of the components of local tensor field quantities and the quantities near the grain boundaries, was obtained with GMC. Finally, the capability of the developed multiscale model linking FEA and GMC to solve real-life-sized structures is demonstrated by successfully analyzing an engine disc component and determining the microstructural scale details of the field quantities. PMID:28773458
Finite coupling corrections to holographic predictions for hot QCD
Waeber, Sebastian; Schafer, Andreas; Vuorinen, Aleksi; ...
2015-11-13
Finite ’t Hooft coupling corrections to multiple physical observables in strongly coupled N=4 supersymmetric Yang-Mills plasma are examined, in an attempt to assess the stability of the expansion in inverse powers of the ’t Hooft coupling λ. Observables considered include thermodynamic quantities, transport coefficients, and quasinormal mode frequencies. Furthermore large λ expansions for quasinormal mode frequencies are notably less well behaved than the expansions of other quantities, we find that a partial resummation of higher order corrections can significantly reduce the sensitivity of the results to the value of λ.
NASA Technical Reports Server (NTRS)
Matolak, D. W.; Apaza, Rafael; Foore, Lawrence R.
2006-01-01
We describe a recently completed wideband wireless channel characterization project for the 5 GHz Microwave Landing System (MLS) extension band, for airport surface areas. This work included mobile measurements at large and small airports, and fixed point-to-point measurements. Mobile measurements were made via transmission from the air traffic control tower (ATCT), or from an airport field site (AFS), to a receiving ground vehicle on the airport surface. The point-to-point measurements were between ATCT and AFSs. Detailed statistical channel models were developed from all these measurements. Measured quantities include propagation path loss and power delay profiles, from which we obtain delay spreads, frequency domain correlation (coherence bandwidths), fading amplitude statistics, and channel parameter correlations. In this paper we review the project motivation, measurement coordination, and illustrate measurement results. Example channel modeling results for several propagation conditions are also provided, highlighting new findings.
Park, Hae-Min; Park, Ju-Hyeong; Kim, Yoon-Woo; Kim, Kyoung-Jin; Jeong, Hee-Jin; Jang, Kyoung-Soon; Kim, Byung-Gee; Kim, Yun-Gon
2013-11-15
In recent years, the improvement of mass spectrometry-based glycomics techniques (i.e. highly sensitive, quantitative and high-throughput analytical tools) has enabled us to obtain a large dataset of glycans. Here we present a database named Xeno-glycomics database (XDB) that contains cell- or tissue-specific pig glycomes analyzed with mass spectrometry-based techniques, including a comprehensive pig glycan information on chemical structures, mass values, types and relative quantities. It was designed as a user-friendly web-based interface that allows users to query the database according to pig tissue/cell types or glycan masses. This database will contribute in providing qualitative and quantitative information on glycomes characterized from various pig cells/organs in xenotransplantation and might eventually provide new targets in the α1,3-galactosyltransferase gene-knock out pigs era. The database can be accessed on the web at http://bioinformatics.snu.ac.kr/xdb.
Time irreversibility and multifractality of power along single particle trajectories in turbulence
NASA Astrophysics Data System (ADS)
Cencini, Massimo; Biferale, Luca; Boffetta, Guido; De Pietro, Massimo
2017-10-01
The irreversible turbulent energy cascade epitomizes strongly nonequilibrium systems. At the level of single fluid particles, time irreversibility is revealed by the asymmetry of the rate of kinetic energy change, the Lagrangian power, whose moments display a power-law dependence on the Reynolds number, as recently shown by Xu et al. [H. Xu et al., Proc. Natl. Acad. Sci. USA 111, 7558 (2014), 10.1073/pnas.1321682111]. Here Lagrangian power statistics are rationalized within the multifractal model of turbulence, whose predictions are shown to agree with numerical and empirical data. Multifractal predictions are also tested, for very large Reynolds numbers, in dynamical models of the turbulent cascade, obtaining remarkably good agreement for statistical quantities insensitive to the asymmetry and, remarkably, deviations for those probing the asymmetry. These findings raise fundamental questions concerning time irreversibility in the infinite-Reynolds-number limit of the Navier-Stokes equations.
A Method to Analyze How Various Parts of Clouds Influence Each Other's Brightness
NASA Technical Reports Server (NTRS)
Varnai, Tamas; Marshak, Alexander; Lau, William (Technical Monitor)
2001-01-01
This paper proposes a method for obtaining new information on 3D radiative effects that arise from horizontal radiative interactions in heterogeneous clouds. Unlike current radiative transfer models, it can not only calculate how 3D effects change radiative quantities at any given point, but can also determine which areas contribute to these 3D effects, to what degree, and through what mechanisms. After describing the proposed method, the paper illustrates its new capabilities both for detailed case studies and for the statistical processing of large datasets. Because the proposed method makes it possible, for the first time, to link a particular change in cloud properties to the resulting 3D effect, in future studies it can be used to develop new radiative transfer parameterizations that would consider 3D effects in practical applications currently limited to 1D theory-such as remote sensing of cloud properties and dynamical cloud modeling.
Directive and enhanced spontaneous emission using shifted cubes nanoantenna
DOE Office of Scientific and Technical Information (OSTI.GOV)
Bahari, B.; Tellez-Limon, R.; Kante, B., E-mail: bkante@ucsd.edu
2016-09-07
Recent studies have demonstrated that nano-patch antennas formed by metallic nanocubes placed on top of a metallic film largely enhance the spontaneous emission rate of quantum emitters due to the confinement of the electromagnetic field in the small nanogap cavity. The popularity of this architecture is, in part, due to the ease in fabrication. In this contribution, we theoretically demonstrate that a dimer formed by two metallic nanocubes embedded in a dielectric medium exhibits enhanced emission rate compared to the nano-patch antenna. Furthermore, we compare the directivity and radiation efficiency of both nanoantennas. From these characteristics, we obtained information aboutmore » the “material efficiency” and the coupling mismatch efficiency between a dipole emitter and the nanoantenna. These quantities provide a more intuitive insight than the Purcell factor or localized density of states, opening new perspectives in nanoantenna design for ultra-directive light emission.« less
Electron Beam Brazing of Titanium for Construction in Space
NASA Technical Reports Server (NTRS)
Flom, Yury
2006-01-01
An extended presence of humans in space requires an in-situ capability to construct various permanent structures to support scientific research, power generation, communication, radiation shielding and other functions. Electron Beam (EB) vacuum brazing has been identified as one of the best joining processes for in-space joining, particular for making a large quantity of permanent joints as required for construction of the sizeable truss structures. Thin wall titanium tubes are perhaps the best choice because of their high stiffness, excellent strength-to-weight ratio and great metal forming and joining ability. An innovative EB vacuum spot brazing process is being developed at Goddard Space Flight Center to be used for robotic as well as human-assisted construction in space. This paper describes experimental results obtained during the initial effort of EB brazing of titanium tubes with the special emphasis on low temperature aluminum filler metals.
NASA Technical Reports Server (NTRS)
Scudder, Nathan F
1934-01-01
This report presents the results of an investigation of the spinning characteristics of NY-1 naval training biplane. The results of flight tests and an analysis based on wind-tunnel test data are given and compared. The primary purpose of the investigation was the determination in flight of the effect of changes in mass distribution along the longitudinal axis, without change of mass quantity or centroid. Other effects were also investigated, such as those due to wing loading, center-of-gravity position, dihedral of wings, control setting, and the removal of a large portion of the fabric from the fin and rudder. The wind tunnel test results used in the numerical analysis were obtained in the 7 by 10 foot wind tunnel through an angle-of-attack.
Ion composition in a noctilucent cloud
NASA Technical Reports Server (NTRS)
Goldberg, R. A.; Witt, G.
1976-01-01
Ion composition at mesospheric altitudes was measured and compared between high and mid-latitude sites under summer daytime conditions. Rocket-borne measurements were made with pumped quadrupole ion mass spectrometers. The mid-latitude data were obtained at Wallops Island, Virginia on June 30, 1973, at 1510 LMT. Large quantities of hydronium cluster ions were observed through 109+, with maximum concentrations at 55+ and 73+. Also, cluster ions of nitric oxide were observed through 84+. The high latitude launch occurred at Kiruna, Sweden on August 2, 1973, at 0700 LMT following visual sighting of a noctilucent cloud on the prior evening. The data near mesopause shows cluster ions, but also a preponderance of heavy ions between 90 and 145 AMU, with groupings 18 AMU apart but unrelated to the more typical cluster ions. One possible set of consistent identifications leads to iron and iron oxide hydrates. These results may suggest the presence of metallic particulates and ions which form hydrated clusters ions.
Liquid crystal thermography and true-colour digital image processing
NASA Astrophysics Data System (ADS)
Stasiek, J.; Stasiek, A.; Jewartowski, M.; Collins, M. W.
2006-06-01
In the last decade thermochromic liquid crystals (TLC) and true-colour digital image processing have been successfully used in non-intrusive technical, industrial and biomedical studies and applications. Thin coatings of TLCs at surfaces are utilized to obtain detailed temperature distributions and heat transfer rates for steady or transient processes. Liquid crystals also can be used to make visible the temperature and velocity fields in liquids by the simple expedient of directly mixing the liquid crystal material into the liquid (water, glycerol, glycol, and silicone oils) in very small quantities to use as thermal and hydrodynamic tracers. In biomedical situations e.g., skin diseases, breast cancer, blood circulation and other medical application, TLC and image processing are successfully used as an additional non-invasive diagnostic method especially useful for screening large groups of potential patients. The history of this technique is reviewed, principal methods and tools are described and some examples are also presented.
Nogueira, Francisco G E; Castro, Isabela A; Bastos, Ana R R; Souza, Guilherme A; de Carvalho, Janice G; Oliveira, Luiz C A
2011-02-28
The leather industry produces a large quantity of solid waste (wet blue leather), which contains a high amount of chromium. After its removal from wet blue leather, a solid collagenic material is recovered, containing high nitrogen levels, which can be used as a nitrogen source in agriculture. In order to take more advantage of the collagen, it was enriched with mineral P and K in order to produce NPK formulations. The objective was also to evaluate the efficiency of such formulations as a nutrient supply for rice plants in an Oxisoil, under greenhouse conditions. The application of PK enriched-collagen formulations resulted in N contents in the vegetative parts and grains of rice plants which were equivalent or superior to those obtained with urea and commercial NPK formulations. Copyright © 2010 Elsevier B.V. All rights reserved.
Identifying financial crises in real time
NASA Astrophysics Data System (ADS)
da Fonseca, Eder Lucio; Ferreira, Fernando F.; Muruganandam, Paulsamy; Cerdeira, Hilda A.
2013-03-01
Following the thermodynamic formulation of a multifractal measure that was shown to enable the detection of large fluctuations at an early stage, here we propose a new index which permits us to distinguish events like financial crises in real time. We calculate the partition function from which we can obtain thermodynamic quantities analogous to the free energy and specific heat. The index is defined as the normalized energy variation and it can be used to study the behavior of stochastic time series, such as financial market daily data. Famous financial market crashes-Black Thursday (1929), Black Monday (1987) and the subprime crisis (2008)-are identified with clear and robust results. The method is also applied to the market fluctuations of 2011. From these results it appears as if the apparent crisis of 2011 is of a different nature to the other three. We also show that the analysis has forecasting capabilities.
Production of mycotoxins by filamentous fungi in untreated surface water.
Oliveira, Beatriz R; Mata, Ana T; Ferreira, João P; Barreto Crespo, Maria T; Pereira, Vanessa J; Bronze, Maria R
2018-04-16
Several research studies reported that mycotoxins and other metabolites can be produced by fungi in certain matrices such as food. In recent years, attention has been drawn to the wide occurrence and identification of fungi in drinking water sources. Due to the large demand of water for drinking, watering, or food production purposes, it is imperative that further research is conducted to investigate if mycotoxins may be produced in water matrices. This paper describes the results obtained when a validated analytical method was applied to detect and quantify the presence of mycotoxins as a result of fungi inoculation and growth in untreated surface water. Aflatoxins B1 and B2, fumonisin B3, and ochratoxin A were detected at concentrations up to 35 ng/L. These results show that fungi can produce mycotoxins in water matrices in a non-negligible quantity and, as such, attention must be given to the presence of fungi in water.
Nanofiltration/reverse osmosis for treatment of coproduced waters
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mondal, S.; Hsiao, C.L.; Wickramasinghe, S.R.
2008-07-15
Current high oil and gas prices have lead to renewed interest in exploration of nonconventional energy sources such as coal bed methane, tar sand, and oil shale. However oil and gas production from these nonconventional sources has lead to the coproduction of large quantities of produced water. While produced water is a waste product from oil and gas exploration it is a very valuable natural resource in the arid Western United States. Thus treated produced water could be a valuable new source of water. Commercially available nanofiltration and low pressure reverse osmosis membranes have been used to treat three producedmore » waters. The results obtained here indicate that the permeate could be put to beneficial uses such as crop and livestock watering. However minimizing membrane fouling will be essential for the development of a practical process. Field Emission Scanning Electron Microscopy imaging may be used to observe membrane fouling.« less
Input-output identification of controlled discrete manufacturing systems
NASA Astrophysics Data System (ADS)
Estrada-Vargas, Ana Paula; López-Mellado, Ernesto; Lesage, Jean-Jacques
2014-03-01
The automated construction of discrete event models from observations of external system's behaviour is addressed. This problem, often referred to as system identification, allows obtaining models of ill-known (or even unknown) systems. In this article, an identification method for discrete event systems (DESs) controlled by a programmable logic controller is presented. The method allows processing a large quantity of observed long sequences of input/output signals generated by the controller and yields an interpreted Petri net model describing the closed-loop behaviour of the automated DESs. The proposed technique allows the identification of actual complex systems because it is sufficiently efficient and well adapted to cope with both the technological characteristics of industrial controllers and data collection requirements. Based on polynomial-time algorithms, the method is implemented as an efficient software tool which constructs and draws the model automatically; an overview of this tool is given through a case study dealing with an automated manufacturing system.
Transient Dynamics of Double Quantum Dots Coupled to Two Reservoirs
NASA Astrophysics Data System (ADS)
Fukadai, Takahisa; Sasamoto, Tomohiro
2018-05-01
We study the time-dependent properties of double quantum dots coupled to two reservoirs using the nonequilibrium Green function method. For an arbitrary time-dependent bias, we derive an expression for the time-dependent electron density of a dot and several currents, including the current between the dots in the wide-band-limit approximation. For the special case of a constant bias, we calculate the electron density and the currents numerically. As a result, we find that these quantities oscillate and that the number of crests in a single period of the current from a dot changes with the bias voltage. We also obtain an analytical expression for the relaxation time, which expresses how fast the system converges to its steady state. From the expression, we find that the relaxation time becomes constant when the coupling strength between the dots is sufficiently large in comparison with the difference of coupling strength between the dots and the reservoirs.
Electric-discharge-pumped nitrogen ion laser
NASA Technical Reports Server (NTRS)
Laudenslager, J. B.; Pacala, T. J.; Wittig, C.
1976-01-01
The routine operation is described of an N2(+) laser oscillating on the first negative band system of N2(+) which is produced in a preionized transverse discharge device. The discharge design incorporates features which favor the efficient production of the excitation transfer reaction of He2(+) with N2. A capacitive discharge switched by means of a high-current grounded grid thyratron is used to meet the design requirement of a volumetric discharge in high-pressure gas mixtures where the electric discharge need not have an ultrafast rise time (greater than 10 nsec) but should be capable of transferring large quantities of stored electric energy to the gas. A peak power of 180 kW in an 8-nsec laser pulse was obtained with a 0.1% mixture of N2 in helium at a total pressure of 3 atm. The most intense laser oscillations were observed on the (0,1) vibrational transition at 427.8 microns.
Studies on cellulose nanocrystals isolated from groundnut shells.
Bano, Saleheen; Negi, Yuvraj Singh
2017-02-10
Today, various renewable biomass resources are accepted as waste material and are mostly burnt or used as cattle feed. The commercial value of these wastes can be increased by utilising them in production of nanomaterials. So, the present work was conducted for isolation of cellulose nanocrystals (CNCs) from groundnut shells which are produced annually as waste in large quantity (∼7 million tons). The structural, thermal, morphological & elemental analyses were assessed through corresponding techniques. Light Scattering studies were performed to analyse more likely weight average molecular weight (M w ) & radius of radius (R g ). The high M w ∼10 5 g/mol obtained for CNCs in lithium chloride (LiCl)/N,N-dimethylacetamide (DMAc) system, was an interesting feature which gets affected by LiCl and polymer concentrations. Solution with high polymer and low LiCl concentration was found to show higher values of M w & R g . Copyright © 2016 Elsevier Ltd. All rights reserved.
Communicating the rigor behind science results
NASA Astrophysics Data System (ADS)
Jackson, R.; Callery, S.
2015-12-01
Communicating the rigor behind science resultsNASA's Global Climate Change website and companion Facebook page have an exceptionally large reach. Moderating the vast quantity of questions, feedback and comments from these public platforms has provided a unique perspective on the way the public views science, the scientific method and how science is funded. Email feedback and social media interactions reveal widespread misperceptions about how science is carried out: There is considerable criticism and suspicion surrounding methods of funding, and the difficulty of obtaining grants is underestimated. There appears to be limited public awareness of the peer review process. This talk will highlight the need for better communication not only of science results, but the process of science--from proposal writing and getting funded to peer-review and fundamental science terminology. As a community of science communicators, we also need to highlight the inaccuracies sometimes introduced by media reports of peer-reviewed science papers.
Gould, S J; Hong, S T; Carney, J R
1998-01-01
The genes for most of the biosynthesis of the kinamycin antibiotics have been cloned and heterologously expressed. Genomic DNA of Streptomyces murayamaensis was partially digested with MboI and a library of approximately 40 kb fragments in E. coli XL1-BlueMR was prepared using the cosmid vector pOJ446. Hybridization with the actI probe from the actinorhodin polyketide synthase genes identified two clusters of polyketide genes. After transferal of these clusters to S. lividans ZX7, expression of one cluster was established by HPLC with photodiode array detection. Peaks were identified from the kin cluster for dehydrorabelomycin, kinobscurinone, and stealthin C, which are known intermediates in kinamycin biosynthesis. Two shunt metabolites, kinafluorenone and seongomycin were also identified. The structure of the latter was determined from a quantity obtained from large-scale fermentation of one of the clones.
Nature of self-diffusion in two-dimensional fluids
NASA Astrophysics Data System (ADS)
Choi, Bongsik; Han, Kyeong Hwan; Kim, Changho; Talkner, Peter; Kidera, Akinori; Lee, Eok Kyun
2017-12-01
Self-diffusion in a two-dimensional simple fluid is investigated by both analytical and numerical means. We investigate the anomalous aspects of self-diffusion in two-dimensional fluids with regards to the mean square displacement, the time-dependent diffusion coefficient, and the velocity autocorrelation function (VACF) using a consistency equation relating these quantities. We numerically confirm the consistency equation by extensive molecular dynamics simulations for finite systems, corroborate earlier results indicating that the kinematic viscosity approaches a finite, non-vanishing value in the thermodynamic limit, and establish the finite size behavior of the diffusion coefficient. We obtain the exact solution of the consistency equation in the thermodynamic limit and use this solution to determine the large time asymptotics of the mean square displacement, the diffusion coefficient, and the VACF. An asymptotic decay law of the VACF resembles the previously known self-consistent form, 1/(t\\sqrt{{ln}t}), however with a rescaled time.
Linear actuation using milligram quantities of CL-20 and TAGDNAT.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Snedigar, Shane; Salton, Jonathan Robert; Tappan, Alexander Smith
2009-07-01
There are numerous applications for small-scale actuation utilizing pyrotechnics and explosives. In certain applications, especially when multiple actuation strokes are needed, or actuator reuse is required, it is desirable to have all gaseous combustion products with no condensed residue in the actuator cylinder. Toward this goal, we have performed experiments on utilizing milligram quantities of high explosives to drive a millimeter-diameter actuator with a stroke of 30 mm. Calculations were performed to select proper material quantities to provide 0.5 J of actuation energy. This was performed utilizing the thermochemical code Cheetah to calculate the impetus for numerous propellants and tomore » select quantities based on estimated efficiencies of these propellants at small scales. Milligram quantities of propellants were loaded into a small-scale actuator and ignited with an ignition increment and hot wire ignition. Actuator combustion chamber pressure was monitored with a pressure transducer and actuator stroke was monitored using a laser displacement meter. Total actuation energy was determined by calculating the kinetic energy of reaction mass motion against gravity. Of the materials utilized, the best performance was obtained with a mixture of 2,4,6,8,10,12-hexanitro-2,4,6,8,10,12-hexaazaisowurtzitane (CL-20) and bis-triaminoguanidinium(3,3{prime}dinitroazotriazolate) (TAGDNAT).« less
Assessing quantities and disposal routes for household hazardous products in the United Kingdom.
Slack, Rebecca J; Zerva, Panagoula; Gronow, Jan R; Voulvoulis, Nikolaos
2005-03-15
The disposal of household products containing hazardous substances (household hazardous wastes; HHW) is of concern due to possible health and environmental effects as a consequence of environmental pollution. The potential risks of disposal are proportional to the amounts of products used and waste generated, but much of the data relating to quantities are old, inconsistent, or nonexistent. Hence, full-scale risk assessment is not yet feasible. This pilot study was aimed at an initial assessment of the amounts of hazardous products used or stored within the household and potential disposal routes. Representatives of 400 households from southeast England were interviewed about socio-demographic factors, perception of the risks associated with the use and disposal of hazardous waste generated in households, quantities of particular products currently in use or stored within the household, and times and methods of disposal of such products. The estimates of quantities obtained were compared with sales figures and waste estimates to improve understanding of product flow through to the HHW stream. The disposal routes investigated demonstrated that most householders claim to use the entire product priorto disposal in the general refuse bin. The relationship with socio-demographic factors demonstrated a difference between neighborhood size and length of residence in a household with regard to product quantities possessed and the disposal habits adopted.
[Chemical weapons and chemical terrorism].
Nakamura, Katsumi
2005-10-01
Chemical Weapons are kind of Weapons of Mass Destruction (WMD). They were used large quantities in WWI. Historically, large quantities usage like WWI was not recorded, but small usage has appeared now and then. Chemical weapons are so called "Nuclear weapon for poor countrys" because it's very easy to produce/possession being possible. They are categorized (1) Nerve Agents, (2) Blister Agents, (3) Cyanide (blood) Agents, (4) Pulmonary Agents, (5) Incapacitating Agents (6) Tear Agents from the viewpoint of human body interaction. In 1997 the Chemical Weapons Convention has taken effect. It prohibits chemical weapons development/production, and Organization for the Prohibition of Chemical Weapons (OPCW) verification regime contributes to the chemical weapons disposal. But possibility of possession/use of weapons of mass destruction by terrorist group represented in one by Matsumoto and Tokyo Subway Sarin Attack, So new chemical terrorism countermeasures are necessary.
1974-01-01
A survey of 763 patients with rheumatoid arthritis and 145 with osteoarthritis in six clinics in New Zealand showed no association between aspirin intake and a score designed to detect analgesic nephropathy. Analgesic nephropathy was diagnosed clinically in three patients taking APC (aspirin, phenacetin, and caffeine or codeine or both) and in one who took aspirin and phenylbutazone and was suspected in one who took aspirin and paracetamol. Isolated aspirin was not implicated. The study showed that most people can take large quantities of salicylates without renal injury. The findings are, however, consistent with the view that there is a risk from APC compounds taken in large quantity, but the numbers at risk in this study were small. Aspirin may have an additive effect with other analgesics in causing renal damage. An increased frequency of urinary tract symptoms in those taking analgesics requires further investigation. PMID:4821007
Community archiving of imaging studies
NASA Astrophysics Data System (ADS)
Fritz, Steven L.; Roys, Steven R.; Munjal, Sunita
1996-05-01
The quantity of image data created in a large radiology practice has long been a challenge for available archiving technology. Traditional methods ofarchiving the large quantity of films generated in radiology have relied on warehousing in remote sites, with courier delivery of film files for historical comparisons. A digital community archive, accessible via a wide area network, represents a feasible solution to the problem of archiving digital images from a busy practice. In addition, it affords a physician caring for a patient access to imaging studies performed at a variety ofhealthcare institutions without the need to repeat studies. Security problems include both network security issues in the WAN environment and access control for patient, physician and imaging center. The key obstacle to developing a community archive is currently political. Reluctance to participate in a community archive can be reduced by appropriate design of the access mechanisms.
Multi-Scale Computational Modeling of Two-Phased Metal Using GMC Method
NASA Technical Reports Server (NTRS)
Moghaddam, Masoud Ghorbani; Achuthan, A.; Bednacyk, B. A.; Arnold, S. M.; Pineda, E. J.
2014-01-01
A multi-scale computational model for determining plastic behavior in two-phased CMSX-4 Ni-based superalloys is developed on a finite element analysis (FEA) framework employing crystal plasticity constitutive model that can capture the microstructural scale stress field. The generalized method of cells (GMC) micromechanics model is used for homogenizing the local field quantities. At first, GMC as stand-alone is validated by analyzing a repeating unit cell (RUC) as a two-phased sample with 72.9% volume fraction of gamma'-precipitate in the gamma-matrix phase and comparing the results with those predicted by finite element analysis (FEA) models incorporating the same crystal plasticity constitutive model. The global stress-strain behavior and the local field quantity distributions predicted by GMC demonstrated good agreement with FEA. High computational saving, at the expense of some accuracy in the components of local tensor field quantities, was obtained with GMC. Finally, the capability of the developed multi-scale model linking FEA and GMC to solve real life sized structures is demonstrated by analyzing an engine disc component and determining the microstructural scale details of the field quantities.
Transportation profiles for MAFC commodities.
DOT National Transportation Integrated Search
2011-08-01
Effective planning for freight in the public sector is often hindered by the difficulty in obtaining reliable estimates of the quantity of : freight commodities flowing between points in the planning area. In an effort to address this issue, the stat...
Asano, Masanari; Basieva, Irina; Khrennikov, Andrei; Ohya, Masanori; Tanaka, Yoshiharu; Yamato, Ichiro
2012-06-01
We developed a quantum-like model describing the gene regulation of glucose/lactose metabolism in a bacterium, Escherichia coli. Our quantum-like model can be considered as a kind of the operational formalism for microbiology and genetics. Instead of trying to describe processes in a cell in the very detail, we propose a formal operator description. Such a description may be very useful in situation in which the detailed description of processes is impossible or extremely complicated. We analyze statistical data obtained from experiments, and we compute the degree of E. coli's preference within adaptive dynamics. It is known that there are several types of E. coli characterized by the metabolic system. We demonstrate that the same type of E. coli can be described by the well determined operators; we find invariant operator quantities characterizing each type. Such invariant quantities can be calculated from the obtained statistical data.
NASA Astrophysics Data System (ADS)
Hendi, S. H.; Panahiyan, S.
2014-12-01
Motivated by the string corrections on the gravity and electrodynamics sides, we consider a quadratic Maxwell invariant term as a correction of the Maxwell Lagrangian to obtain exact solutions of higher dimensional topological black holes in Gauss-Bonnet gravity. We first investigate the asymptotically flat solutions and obtain conserved and thermodynamic quantities which satisfy the first law of thermodynamics. We also analyze thermodynamic stability of the solutions by calculating the heat capacity and the Hessian matrix. Then, we focus on horizon-flat solutions with an anti-de Sitter (AdS) asymptote and produce a rotating spacetime with a suitable transformation. In addition, we calculate the conserved and thermodynamic quantities for asymptotically AdS black branes which satisfy the first law of thermodynamics. Finally, we perform thermodynamic instability criterion to investigate the effects of nonlinear electrodynamics in canonical and grand canonical ensembles.
Form of prior for constrained thermodynamic processes with uncertainty
NASA Astrophysics Data System (ADS)
Aneja, Preety; Johal, Ramandeep S.
2015-05-01
We consider the quasi-static thermodynamic processes with constraints, but with additional uncertainty about the control parameters. Motivated by inductive reasoning, we assign prior distribution that provides a rational guess about likely values of the uncertain parameters. The priors are derived explicitly for both the entropy-conserving and the energy-conserving processes. The proposed form is useful when the constraint equation cannot be treated analytically. The inference is performed using spin-1/2 systems as models for heat reservoirs. Analytical results are derived in the high-temperatures limit. An agreement beyond linear response is found between the estimates of thermal quantities and their optimal values obtained from extremum principles. We also seek an intuitive interpretation for the prior and the estimated value of temperature obtained therefrom. We find that the prior over temperature becomes uniform over the quantity kept conserved in the process.
Application of the Probabilistic Dynamic Synthesis Method to the Analysis of a Realistic Structure
NASA Technical Reports Server (NTRS)
Brown, Andrew M.; Ferri, Aldo A.
1998-01-01
The Probabilistic Dynamic Synthesis method is a new technique for obtaining the statistics of a desired response engineering quantity for a structure with non-deterministic parameters. The method uses measured data from modal testing of the structure as the input random variables, rather than more "primitive" quantities like geometry or material variation. This modal information is much more comprehensive and easily measured than the "primitive" information. The probabilistic analysis is carried out using either response surface reliability methods or Monte Carlo simulation. A previous work verified the feasibility of the PDS method on a simple seven degree-of-freedom spring-mass system. In this paper, extensive issues involved with applying the method to a realistic three-substructure system are examined, and free and forced response analyses are performed. The results from using the method are promising, especially when the lack of alternatives for obtaining quantitative output for probabilistic structures is considered.
Application of the Probabilistic Dynamic Synthesis Method to Realistic Structures
NASA Technical Reports Server (NTRS)
Brown, Andrew M.; Ferri, Aldo A.
1998-01-01
The Probabilistic Dynamic Synthesis method is a technique for obtaining the statistics of a desired response engineering quantity for a structure with non-deterministic parameters. The method uses measured data from modal testing of the structure as the input random variables, rather than more "primitive" quantities like geometry or material variation. This modal information is much more comprehensive and easily measured than the "primitive" information. The probabilistic analysis is carried out using either response surface reliability methods or Monte Carlo simulation. In previous work, the feasibility of the PDS method applied to a simple seven degree-of-freedom spring-mass system was verified. In this paper, extensive issues involved with applying the method to a realistic three-substructure system are examined, and free and forced response analyses are performed. The results from using the method are promising, especially when the lack of alternatives for obtaining quantitative output for probabilistic structures is considered.
Measurement of some potentially hazardous materials in the atmosphere of rubber factories.
Nutt, A
1976-01-01
Two separate topics of work are outlined: methods for the measurement of chlorinated monomers in PVC and polychloroprene, and also methods for the measurement of these materials in factory air. Typical results which have been obtained in supplies of raw materials, in finished products, and in the working atmosphere at manufacturing operations are given. The second topic concerns the measurement of benzo[a]pyrene in the atmosphere of a tire manufacturing plant. This material is present in trace quantities in the mineral oils and carbon blacks used by the industry. The atmospheric concentrations present at various processes in this plant were measured on a daily basis over a period of two years, and the results obtained compared with results taken concurrently from an outside air station. It is shown that no significant quantities of benzo[a]pyrene are produced by tire manufacturing operations. Images FIGURE 1. FIGURE 2. FIGURE 4. FIGURE 5. PMID:1026396