Seeking Common Ground: Deliberative Democracy and Sustainable Communities.

ERIC Educational Resources Information Center

Hyman, Drew; Clinehens, Brad

Public deliberation, sometimes called deliberative democracy, offers alternatives to what are often adversarial governmental debates and hearings. This paper provides a case example of applying the deliberative democracy process to development issues and an analysis of data comparing the effectiveness of the process for creating a consensus for…

Working with Culture: Psychotherapeutic Interventions with Ethnic Minority Children and Adolescents.

ERIC Educational Resources Information Center

Vargas, Luis A., Ed.; Koss-Chioino, Joan D., Ed.

This book presents essays concerning culturally responsive psychotherapeutic interventions for specific problems commonly experienced by ethnic-minority youth. Each essay offers case examples, along with a clinical how-to approach for dealing with problems such as cross-racial foster care, gang involvement, child abuse, and substance abuse. Essays…

An Ecological Perspective on Deafness.

ERIC Educational Resources Information Center

Harvey, Michael A.; Dym, Barry

1988-01-01

The article offers an ecological view of deafness through identification of the hierarchically arranged, bio-psych-social levels which influence development and the sequences of interaction within and between levels. The organization of ecological fields is described by a cybernetic model from family therapy. A detailed case example is presented.…

The Effects of Meal Schedule and Quantity on Problematic Behavior.

ERIC Educational Resources Information Center

Wacker, David P.; And Others

1996-01-01

Two case examples (a toddler with severe developmental delays and a 7-year old with severe mental retardation) illustrating effects of meal schedule and food quantity on displays of problematic behavior are offered. Brief functional analyses of aberrant behavior provided useful information for interpreting distinct patterns of behavior. (DB)

Transnational Academic Mobility, Knowledge, and Identity Capital

ERIC Educational Resources Information Center

Kim, Terri

2010-01-01

This article begins with the contemporary context of transnational academic mobility, and sketches a typology of mobile academics according to their self-identification. UK examples are offered as the main case study here. The article will then explore the relations of mobile academics and their embodied and encultured knowledge. It employs a…

Orthodontics

PubMed Central

Hemrend, Bernard; Altuna, Gurkan; Tompson, Bryan

1989-01-01

The authors of this article offer an introduction to the field of orthodontics. They present the latest advances in orthodontic appliances and some of the possible consequences of orthodontic treatment. They discuss a number of cases and offer examples of some of the more common problems that the orthodontist is asked to treat. Such cases include severe Class II, division 1 malocclusion, surgical orthodontics, “long-face” syndrome, adult orthodontics-TMJ-periodontics, late adult growth, and post-retention changes. Practical information useful to the physician who encounters patient with these disorders is balanced with good research data to support the various claims. ImagesFigure 1Figure 2Figure 3Figure 4Figure 5Figure 6Figure 7Figure 8Figure 9 PMID:21249042

Testing the Consolidated Framework for Implementation Research on health care innovations from South Yorkshire.

PubMed

Ilott, Irene; Gerrish, Kate; Booth, Andrew; Field, Becky

2013-10-01

There is an international imperative to implement research into clinical practice to improve health care. Understanding the dynamics of change requires knowledge from theoretical and empirical studies. This paper presents a novel approach to testing a new meta theoretical framework: the Consolidated Framework for Implementation Research. The utility of the Framework was evaluated using a post hoc, deductive analysis of 11 narrative accounts of innovation in health care services and practice from England, collected in 2010. A matrix, comprising the five domains and 39 constructs of the Framework was developed to examine the coherence of the terminology, to compare results across contexts and to identify new theoretical developments. The Framework captured the complexity of implementation across 11 diverse examples, offering theoretically informed, comprehensive coverage. The Framework drew attention to relevant points in individual cases together with patterns across cases; for example, all were internally developed innovations that brought direct or indirect patient advantage. In 10 cases, the change was led by clinicians. Most initiatives had been maintained for several years and there was evidence of spread in six examples. Areas for further development within the Framework include sustainability and patient/public engagement in implementation. Our analysis suggests that this conceptual framework has the potential to offer useful insights, whether as part of a situational analysis or by developing context-specific propositions for hypothesis testing. Such studies are vital now that innovation is being promoted as core business for health care. © 2012 John Wiley & Sons Ltd.

[Prosthetic rehabilitation of patients with parodontitis based upon the use of 3D-technologies--clinical case example].

PubMed

Riakhovskiĭ, A N

2011-01-01

Clinical case of prosthetic rehabilitation of patient (female) with generalized parodontitis complicated by defects and deformations of dentitions was offered. Using 3D-technologies position of teeth was corrected with the help of a series of temporary transparent splints-modifiers with subsequent guy splintage and esthetic 3D-planning of front teeth forms. Teeth forms correction was made by composite using preliminary prepared templet.

Live Cases: Service-Learning Consulting Projects in Business Courses.

ERIC Educational Resources Information Center

Godar, Susan Hayes

2000-01-01

Offers suggestions to community service coordinators on how to encourage the use of service learning projects among business faculty in the form of consulting for non-profit organizations. Provides examples of projects in marketing and management courses and discusses how to implement this type of activity in a business course. (EV)

Strategies for Reforming University/State Relationships: Australia's Experience Sets Examples.

ERIC Educational Resources Information Center

McGuire, Harriet C.

1997-01-01

The World Bank's recommendations for higher education policy in Africa offer an appropriate framework for comparison with recent educational policy changes in Australia, particularly in the area of university financing. Australia provides a case study of how national policies have had a dramatic and rapid effect on education and have quickly…

Explicating Practicum Program Theory: A Case Example in Human Ecology

ERIC Educational Resources Information Center

Chandler, Kathryn M. M.; Williamson, Deanna L.

2013-01-01

This study explicated the theory underpinning the Human Ecology Practicum Program offered in the Department of Human Ecology at the University of Alberta. The program has operated for 40 years but never been formally evaluated. Using a document analysis, focus group and individual interviews, and a stakeholder working group, we explored…

Designing a Programmatic Digital Learning Environment: Lessons from Prototyping

ERIC Educational Resources Information Center

Gal, Diane; Lewis, Mark

2018-01-01

Promoted as a way to enhance learning and improve efficiencies, the steady rise of technology adoption across higher education has created both new opportunities and new challenges. Borrowing principles of design thinking and related user- or learner-centered design practices, this descriptive case study offers an example of how institutions of…

Entrepreneurship Education for Executive MBAs: The Case of a Caribbean Business School

ERIC Educational Resources Information Center

Allahar, Haven; Brathwaite, Candace

2017-01-01

Entrepreneurship courses are now a feature of the curricula of many tertiary-level business schools. While there is a growing body of research on the subject of entrepreneurship education and learning, studies of the executive master of business administration (EMBA) are relatively sparse. This article offers an example of an entrepreneurship…

Making Outreach Visible: A Guide to Documenting Professional Service and Outreach. AAHE Forum on Faculty Roles and Rewards.

ERIC Educational Resources Information Center

Driscoll, Amy; Lynton, Ernest A.

This guidebook is intended to help faculty and administrators, and departments and schools, document faculty professional service and outreach, offering detailed examples of work from various universities. Following a Foreword by R. Eugene Rice, short introductory chapters make the case for professional service, define professional…

Globalization of the pharmaceutical industry and the growing dependency of developing countries: the case of Turkey.

PubMed

Semin, Semih; Güldal, Dilek

2008-01-01

In developing countries, the effect of globalization on the pharmaceutical sector has resulted in a decrease in exportation and domestic production, accompanied by an increase in importation of pharmaceuticals and a rise in prices and expenditures. As an example of a developing country, Turkey has been facing the long-standing and increasing pressure of global regulations placed on its pharmaceutical sector. This has led to an increasing dependency on multinational companies and a gradual deterioration of an already weakened domestic pharmaceutical sector. This case study of Turkey offers points to consider in the world of increasing globalization, as it offers lessons on ways of examining the effects of globalization on the pharmaceutical industry of developing countries.

Using Framework Analysis in nursing research: a worked example.

PubMed

Ward, Deborah J; Furber, Christine; Tierney, Stephanie; Swallow, Veronica

2013-11-01

To demonstrate Framework Analysis using a worked example and to illustrate how criticisms of qualitative data analysis including issues of clarity and transparency can be addressed. Critics of the analysis of qualitative data sometimes cite lack of clarity and transparency about analytical procedures; this can deter nurse researchers from undertaking qualitative studies. Framework Analysis is flexible, systematic, and rigorous, offering clarity, transparency, an audit trail, an option for theme-based and case-based analysis and for readily retrievable data. This paper offers further explanation of the process undertaken which is illustrated with a worked example. Data were collected from 31 nursing students in 2009 using semi-structured interviews. The data collected are not reported directly here but used as a worked example for the five steps of Framework Analysis. Suggestions are provided to guide researchers through essential steps in undertaking Framework Analysis. The benefits and limitations of Framework Analysis are discussed. Nurses increasingly use qualitative research methods and need to use an analysis approach that offers transparency and rigour which Framework Analysis can provide. Nurse researchers may find the detailed critique of Framework Analysis presented in this paper a useful resource when designing and conducting qualitative studies. Qualitative data analysis presents challenges in relation to the volume and complexity of data obtained and the need to present an 'audit trail' for those using the research findings. Framework Analysis is an appropriate, rigorous and systematic method for undertaking qualitative analysis. © 2013 Blackwell Publishing Ltd.

Use of Business-Naming Practices to Delineate Vernacular Regions: A Michigan Example

ERIC Educational Resources Information Center

Liesch, Matthew; Dunklee, Linda M.; Legg, Robert J.; Feig, Anthony D.; Krause, Austin Jena

2015-01-01

This article provides a history of efforts to map vernacular regions as context for offering readers a way of using business directories in order to construct a GIS-based map of vernacular regions. With Michigan as a case study, the article discusses regional-naming conventions, boundaries, and inclusions and omissions of areas from regional…

The Achieving Success Everyday Group Counseling Model: Implications for Professional School Counselors

ERIC Educational Resources Information Center

Steen, Sam; Henfield, Malik S.; Booker, Beverly

2014-01-01

This article presents the Achieving Success Everyday (ASE) group counseling model, which is designed to help school counselors integrate students' academic and personal-social development into their group work. We first describe this group model in detail and then offer one case example of a middle school counselor using the ASE model to conduct a…

What Makes Racial Diversity Work in Higher Education: Academic Leaders Present Successful Policies and Strategies.

ERIC Educational Resources Information Center

Hale, Frank W., Jr., Ed.

The essays in this collection establish the case for racial diversity , outline the challenges diversity offers the academic community, presents examples of how some institutions have developed successful models of diversity, and discusses how the history of racial diversity has influenced aspects of diversity today. Following a foreword,…

In Search of the Dream: Designing Schools and Classrooms That Work for High Potential Students from Diverse Cultural Backgrounds

ERIC Educational Resources Information Center

Tomlinson, Carol Ann; Ford, Donna Y.; Reis, Sally M.; Briggs, Christine J.; Strickland, Cindy A.

2004-01-01

This book offers guiding principles for culturally diverse environments and curricular choices to support multicultural inclusiveness. Case studies provide examples of exemplary gifted education programs, emphasizing the aspects of the program that best respond to diverse student populations. Subsequent chapters on gifted and general education…

Motivating Students to Offer Their Best: Evidence Based Effective Course Design

ERIC Educational Resources Information Center

Stearns, Susan A.

2013-01-01

Sometimes we question whether students are incapable or capable and/or willing or unwilling in regards to their academics. This study determined where students lie in regards to these concepts and showed one example of motivating students to do their best via course design, in this particular case by the use of a writing process model.

Understanding Teamwork in the Provision of Cancer Care: Highlighting the Role of Trust.

PubMed

Lazzara, Elizabeth H; Keebler, Joseph R; Day, Soosi; DiazGranados, Deborah; Pan, Minggui; King, Michael A; Tu, Shin-Ping

2016-11-01

Team science research has indicated that trust is a critical variable of teamwork, contributing greatly to a team's performance. Trust has long been examined in health care with research focusing on the development of trust by patients with their health care practitioners. Studies have indicated that trust is linked to patient satisfaction, adherence to treatment, continuity of care, and improved outcomes. We explore the construct of trust using a case example of a patient who received a surgical procedure for a precancerous polyp. We apply the principle of trust to the case as well as present the literature on trust and key definitions for understanding trust. Additionally, we apply the definitions presented to the specific case example by highlighting moments where trust is developed or violated. Lastly, we offer insights to health care practitioners on the development of trust in their own patient interactions to improve care.

Understanding Teamwork in the Provision of Cancer Care: Highlighting the Role of Trust

PubMed Central

Keebler, Joseph R.; Day, Soosi; DiazGranados, Deborah; Pan, Minggui; King, Michael A.; Tu, Shin-Ping

2016-01-01

Team science research has indicated that trust is a critical variable of teamwork, contributing greatly to a team’s performance. Trust has long been examined in health care with research focusing on the development of trust by patients with their health care practitioners. Studies have indicated that trust is linked to patient satisfaction, adherence to treatment, continuity of care, and improved outcomes. We explore the construct of trust using a case example of a patient who received a surgical procedure for a precancerous polyp. We apply the principle of trust to the case as well as present the literature on trust and key definitions for understanding trust. Additionally, we apply the definitions presented to the specific case example by highlighting moments where trust is developed or violated. Lastly, we offer insights to health care practitioners on the development of trust in their own patient interactions to improve care. PMID:27601505

48 CFR 25.504 - Evaluation Examples.

Code of Federal Regulations, 2011 CFR

2011-10-01

... PROGRAMS FOREIGN ACQUISITION Evaluating Foreign Offers-Supply Contracts 25.504 Evaluation Examples. The... examples assume that the contracting officer has eliminated all offers that are unacceptable for reasons... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false Evaluation Examples. 25...

Determining rules for closing customer service centers: A public utility company's fuzzy decision

NASA Technical Reports Server (NTRS)

Dekorvin, Andre; Shipley, Margaret F.

1992-01-01

In the present work, we consider the general problem of knowledge acquisition under uncertainty. A commonly used method is to learn by examples. We observe how the expert solves specific cases and from this infer some rules by which the decision was made. Unique to this work is the fuzzy set representation of the conditions or attributes upon which the decision make may base his fuzzy set decision. From our examples, we infer certain and possible rules containing fuzzy terms. It should be stressed that the procedure determines how closely the expert follows the conditions under consideration in making his decision. We offer two examples pertaining to the possible decision to close a customer service center of a public utility company. In the first example, the decision maker does not follow too closely the conditions. In the second example, the conditions are much more relevant to the decision of the expert.

The Science Manager's Guide to Case Studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Branch, Kristi M.; Peffers, Melissa S.; Ruegg, Rosalie T.

2001-09-24

This guide takes the science manager through the steps of planning, implementing, validating, communicating, and using case studies. It outlines the major methods of analysis, describing their relative merits and applicability while providing relevant examples and sources of additional information. Well-designed case studies can provide a combination of rich qualitative and quantitative information, offering valuable insights into the nature, outputs, and longer-term impacts of the research. An objective, systematic, and credible approach to the evaluation of U.S. Department of Energy Office of Science programs adds value to the research process and is the subject of this guide.

Sexual Misconduct and Enactment

PubMed Central

Plakun, Eric M.

1999-01-01

Sexual misconduct remains a significant problem in the behavioral health professions. Although it is tempting to view sexual misconduct as perpetrated by “bad” clinicians against patients who are “victims,” this is an oversimplification of a complex problem. In this article, the author explores the psychoanalytic concept of enactment as a mechanism that can lead well-meaning clinicians to engage in sexual misconduct; defines enactment and differentiates it from near neighbor phenomena; uses case examples to illustrate how enactments may lead to sexual misconduct or may offer opportunities to deepen and enhance psychotherapeutic work; and offers recommendations for prevention of sexual misconduct. PMID:10523431

The Teaching Portfolio: Capturing the Scholarship in Teaching.

ERIC Educational Resources Information Center

Edgerton, Russell; And Others

This report argues a case for the use of professional teaching portfolios by educators in higher education, advances a point of view about portfolio issues, and offers examples of portfolio entries. A work-sample-plus-reflection model is presented as a guide for what might be included in a portfolio and why it might be used at a particular campus.…

Rapid Prototyping as Method for Developing Instructional Strategies for Supporting Computer-Mediated Communication among University Students

ERIC Educational Resources Information Center

Knowlton, Dave S.

2006-01-01

Because rapid prototyping results in the quick development of curriculum, materials, and processes, it is a form of design that could be particularly useful to professors in higher education. Yet, literature documenting the use of rapid prototyping in higher education is scarce. This paper offers a case example of rapid prototyping being used as a…

Schools Going Solar: A Guide to Schools Enjoying the Power of Solar Energy. Volume 2.

ERIC Educational Resources Information Center

Hitchcock, Susan Tyler

This companion document updates an April 1998 volume on designing schools to use solar energy as a power source. Volume 2 presents numerous case studies of solar installations in new and existing schools across the United States and Europe, updates and presents new examples of solar education programs, and offers an updated resource listing of…

Best Practices in Academic Assessment in Higher Education: A Case in Formative and Shared Assessment

ERIC Educational Resources Information Center

López Pastor, Víctor M.

2011-01-01

The aim of this article is three-fold: (a) to present an example of best practices in formative assessment in university instruction, offering three different methods of learning and assessment to pass a subject; (b) to analyze differences in academic performance depending on method of learning and assessment chosen; (c) to consider professors'…

The Relevance of Campus Outdoor Recreation Programs to Higher Education: A University of Utah Example

ERIC Educational Resources Information Center

Dustin, Daniel; Furman, Nate; Bricker, Nate; Cederquist, John; Schumann, Scott

2017-01-01

This paper illustrates the relevance of campus recreation to higher education through a University of Utah case study. Offering Utah's Experiential Learning and Outdoor Recreation Education (U-EXPLORE) program as our exemplar, we advance four lines of thought. First, we establish the relationship between an active body and an active mind. Second,…

Education as Instrument or as Empowerment? Untangling White Privilege in the Politics of Ethnic Studies: The Case of the Tucson Unified School District

ERIC Educational Resources Information Center

Dotts, Brian W.

2015-01-01

Public school curriculum battles offer great examples for illustrating how politics saturates education policy, particularly in the State of Texas. However, Arizona has emerged as another peculiar contender in contemporary battles to control high school curricula. Curriculum battles have deep historical roots in Arizona and elsewhere that go…

Treating the Tough Adolescent: A Family-Based, Step-by-Step Guide. The Guilford Family Therapy Series.

ERIC Educational Resources Information Center

Sells, Scott P.

A model for treating difficult adolescents and their families is presented. Part 1 offers six basic assumptions about the causes of severe behavioral problems and presents the treatment model with guidelines necessary to address each of these six causes. Case examples highlight and clarify major points within each of the 15 procedural steps of the…

Mentoring Student Participation in Undergraduate Research: A Case Study of Twists and Turns from Two Perspectives

ERIC Educational Resources Information Center

Perez, Ismael; Bowers, Janet; Salamon, Peter

2017-01-01

Undergraduate research experiences provide excellent examples of high-impact practices. They rely on inquiry-based learning to provide important capstone experiences for the students. However, they are time-intensive for mentor faculty. In an attempt to scale up our faculty's ability to offer such experiences, we combined a number of projects into…

When Does an Argument Use a Generic Example?

ERIC Educational Resources Information Center

Yopp, David A.; Ely, Rob

2016-01-01

We offer criteria that an observer can use to determine whether an argument that uses an example to argue for a general claim appeals to that example generically. We review existing literature on generic example and note the strengths of each contribution, as well as inconsistencies among uses of the term. We offer several examples from the…

Using National Newspapers in the College Classroom: Resources To Improve Teaching and Learning. The First-Year Experience & Students in Transition. Monograph Series, No. 28.

ERIC Educational Resources Information Center

Knowlton, Steven R., Ed.; Barefoot, Betsy O., Ed.

Thirty-eight brief articles first make the case for using newspapers in the college classroom and then offer examples of how newspapers should be used in the following subject areas: business (advertising, business writing, management); English (composition, research writing, women's studies); first-year seminar (honors seminar, reading, study…

The Catholic child, adolescent, and family.

PubMed

Murrell, Kevin

2004-01-01

This article identifies core features of Catholic spiritual and religious tradition and worldview. It reviews clinical implications of this worldview in working with the psychiatric problems of Catholic children and adolescents. Core Catholic beliefs and practices are discussed, with case examples illustrating principles of assessment and treatment. Collaboration between child and adolescent psychiatrists and Catholic clergy and counselors is encouraged, and recommendations for successful collaborative efforts are offered.

Accelerated Learning and Retention: Literature Review and Workshop Review

DTIC Science & Technology

2011-03-01

effectiveness, and the committee found that neurolinguistic programming (NLP) had promise, but had not been shown to be effective. They also...Meier, 2000) have used accelerated learning in training programs . Table 3 provides concrete examples of some of the results offered by approaches...minute counts (as is the case in accelerated programs ), motivation is of critical importance. This is one reason why training interventions aimed to

Student-Staff Partnerships as Transformational: The "Students as Learners and Teachers" Program as a Case Study in Changing Higher Education

ERIC Educational Resources Information Center

Cook-Sather, Alison

2014-01-01

In this article the author offers an example of a student-staff partnership program based in a higher education context in the United States. This program positions undergraduate students as pedagogical consultants to academic staff. The goal of the program is to counter traditional hierarchies and imbalanced power relations and foster a shift in…

Comment faire de la grammaire sans trahir le discours: Le cas des exercices grammaticaux (How to Teach Grammar without Betraying Discourse: The Case of Grammatical Exercises).

ERIC Educational Resources Information Center

Calve, Pierre

1994-01-01

Discusses the various functions of grammar in second-language (SL) education, and examines the relationship between discourse and grammar in SL education. Two problems are then examined concerning the relationship between discourse and grammar within grammatical exercises, and with the help of concrete examples, suggestions are offered to better…

Parallel-vector unsymmetric Eigen-Solver on high performance computers

NASA Technical Reports Server (NTRS)

Nguyen, Duc T.; Jiangning, Qin

1993-01-01

The popular QR algorithm for solving all eigenvalues of an unsymmetric matrix is reviewed. Among the basic components in the QR algorithm, it was concluded from this study, that the reduction of an unsymmetric matrix to a Hessenberg form (before applying the QR algorithm itself) can be done effectively by exploiting the vector speed and multiple processors offered by modern high-performance computers. Numerical examples of several test cases have indicated that the proposed parallel-vector algorithm for converting a given unsymmetric matrix to a Hessenberg form offers computational advantages over the existing algorithm. The time saving obtained by the proposed methods is increased as the problem size increased.

Pandemic influenza preparedness and response in Israel: a unique model of civilian-defense collaboration.

PubMed

Kohn, Sivan; Barnett, Daniel J; Leventhal, Alex; Reznikovich, Shmuel; Oren, Meir; Laor, Danny; Grotto, Itamar; Balicer, Ran D

2010-07-01

In April 2009, the World Health Organization announced the emergence of a novel influenza A(H1N1-09) virus and in June 2009 declared the outbreak a pandemic. The value of military structures in responding to pandemic influenza has become widely acknowledged in recent years. In 2005, the Israeli Government appointed the Ministry of Defense to be in charge of national preparedness and response for a severe pandemic influenza scenario. The Israeli case offers a unique example of civilian-defense partnership where the interface between the governmental, military and civilian spheres has formed a distinctive structure. The Israeli pandemic preparedness protocols represent an example of a collaboration in which aspects of an inherently medical problem can be managed by the defense sector. Although distinctive concepts of the model are not applicable to all countries, it offers a unique forum for governments and international agencies to evaluate this interface within the context of pandemic influenza.

Science and the Energy Security Challenge: The Example of Solid-State Lighting

ScienceCinema

Philips, Julia [Sandia

2017-12-09

Securing a viable, carbon neutral energy future for humankind will require an effort of gargantuan proportions. As outlined clearly in a series of workshops sponsored by the DOE Office of Basic Energy Sciences (http://www.sc.doe.gov/bes/reports/list.html), fundamental advances in scientific understanding are needed to broadly implement many of the technologies that are held out as promising options to meet future energy needs, ranging from solar energy, to nuclear energy, to approaches to clean combustion. Using solid state lighting based on inorganic materials as an example, I will discuss some recent results and new directions, emphasizing the multidisciplinary, team nature of the endeavor. I will also offer some thoughts about how to encourage translation of the science into attractive, widely available products – a significant challenge that cannot be ignored. This case study offers insight into approaches that are likely to be beneficial for addressing other aspects of the energy security challenge.

Trust Building as a Strategy to Avoid Unintended Consequences of Education. The Case Study of International Summer Camps Designed to Promote Peace and Intercultural Dialogue among Adolescents

ERIC Educational Resources Information Center

Farini, Federico

2014-01-01

This article aims to offer both a theoretical contribution and examples of practices of trust building in peace education; the article presents an empirical analysis of videotaped interactions in the context of peace education activities in international groups of adolescents. The analysis regards two international summer camps promoted by the…

Ethics consultation on demand: concepts, practical experiences and a case study.

PubMed

Reiter-Theil, S

2000-06-01

Despite the increasing interest in clinical ethics, ethics consultation as a professional service is still rare in Europe. In this paper I refer to examples in the United States. In Germany, university hospitals and medical faculties are still hesitant about establishing yet another "committee". One of the reasons for this hesitation lies in the ignorance that exists here about how to provide medical ethics services; another reason is that medical ethics itself is not yet institutionalised at many German universities. The most important obstacle, however, may be that medical ethics has not yet demonstrated its relevance to the needs of those caring for patients. The Centre for Ethics and Law, Freiburg, has therefore taken a different approach from that offered elsewhere: clinical ethics consultation is offered on demand, the consultation being available to clinician(s) in different forms. This paper describes our experiences with this approach; practical issues are illustrated by a case study.

Cognitive Behavioural Suicide Prevention for Male Prisoners: Case examples

PubMed Central

Pratt, Daniel; Gooding, Patricia; Awenat, Yvonne; Eccles, Steve; Tarrier, Nicholas

2015-01-01

Suicide is a serious public health problem but a problem that is preventable. This complex and challenging problem is particularly prevalent amongst prisoners; associated with a five-fold increase in risk compared to the general community. Being in prison can lead people to experience fear, distrust, lack of control, isolation, and shame, which is often experienced as overwhelming and intolerable with some choosing suicide as a way to escape. Few effective psychological interventions exist to prevent suicide although cognitive behaviour therapies appear to offer some promise. Offering cognitive behaviour suicide prevention (CBSP) therapy to high risk prisoners may help to reduce the likelihood of preventable self-inflicted deaths. In this paper we present three cases drawn from a randomised controlled trial designed to investigate the feasibility of CBSP for male prisoners. Implications of the current findings for future research and clinical practice are considered. PMID:27713616

[Application of nested case-control study on safe evaluation of post-marketing traditional Chinese medicine injection].

PubMed

Xiao, Ying; Zhao, Yubin; Xie, Yanming

2011-10-01

The nested case-control study design (or the case-control in a cohort study) is described here as a new study design used in safe evaluation of post-marketing traditional Chinese medicine injection. In the nested case-control study, cases of a disease that occur in a defined cohort are identified and, for each, a specified number of matched controls is selected from among those in the cohort who have not developed the disease by the time of disease occurrence in the case. For many research questions, the nested case-control design potentially offers impressive reductions in costs and efforts of data collection and analysis compared with the full cohort approach, with relatively minor loss in statistical efficiency. The nested case-control design is particularly advantageous for studies in safe evaluation of post-marketing traditional Chinese medicine injection. Some examples of the application of nested case-control study were given.

Socratic Circles in World History: Reflections on a Year in Dialogue

ERIC Educational Resources Information Center

Thomas, Corey; Goering, Christian Z.

2018-01-01

This article examines and offers insights to a year of Socratic circles in the context of a world history classroom. Grounding this practice in relevant research before offering examples from the classroom and providing advice to practitioners, this discussion strategy offers an antidote to the often divisive and destructive examples of…

Knowledge acquisition for case-based reasoning systems

NASA Technical Reports Server (NTRS)

Riesbeck, Christopher K.

1988-01-01

Case-based reasoning (CBR) is a simple idea: solve new problems by adapting old solutions to similar problems. The CBR approach offers several potential advantages over rule-based reasoning: rules are not combined blindly in a search for solutions, solutions can be explained in terms of concrete examples, and performance can improve automatically as new problems are solved and added to the case library. Moving CBR for the university research environment to the real world requires smooth interfaces for getting knowledge from experts. Described are the basic elements of an interface for acquiring three basic bodies of knowledge that any case-based reasoner requires: the case library of problems and their solutions, the analysis rules that flesh out input problem specifications so that relevant cases can be retrieved, and the adaptation rules that adjust old solutions to fit new problems.

Considerations for the effects of military deployment on children and families.

PubMed

Lincoln, Alan J; Sweeten, Kathie

2011-01-01

Children of deployed military personnel represent a unique subculture in the United States. While many children exhibit high levels of resiliency, others will struggle with the impact of a parent who has gone to war. This article looks at some of the stressors of deployment as experienced by children and offers three case examples as well as clinical considerations for those who work with the children and families of the deployed.

12 CFR Appendix A to Part 610 - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2013 CFR

2013-01-01

... mechanism function for a specific loan product is communicated without authority to negotiate the rate. (ii... details of that offer. (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain...

12 CFR Appendix A to Subpart F of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2011 CFR

2011-01-01

... mechanism function for a specific loan product is communicated without authority to negotiate the rate. (ii...) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain.” (1) Offering or...

12 CFR Appendix A to Part 610 - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2011 CFR

2011-01-01

... mechanism function for a specific loan product is communicated without authority to negotiate the rate. (ii... details of that offer. (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain...

12 CFR Appendix A to Subpart B of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2014 CFR

2014-01-01

... by the bank's loan approval mechanism function for a specific loan product is communicated without... details of that offer. (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain...

12 CFR Appendix A to Subpart F of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2012 CFR

2012-01-01

... mechanism function for a specific loan product is communicated without authority to negotiate the rate. (ii...) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain.” (1) Offering or...

12 CFR Appendix A to Subpart F of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2014 CFR

2014-01-01

... mechanism function for a specific loan product is communicated without authority to negotiate the rate. (ii...) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain.” (1) Offering or...

12 CFR Appendix A to Subpart B of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2012 CFR

2012-01-01

... by the bank's loan approval mechanism function for a specific loan product is communicated without... details of that offer. (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain...

12 CFR Appendix A to Subpart B of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2011 CFR

2011-01-01

... by the bank's loan approval mechanism function for a specific loan product is communicated without... details of that offer. (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain...

12 CFR Appendix A to Part 610 - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2012 CFR

2012-01-01

... mechanism function for a specific loan product is communicated without authority to negotiate the rate. (ii... details of that offer. (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain...

12 CFR Appendix A to Subpart F of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2013 CFR

2013-01-01

... mechanism function for a specific loan product is communicated without authority to negotiate the rate. (ii...) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain.” (1) Offering or...

12 CFR Appendix A to Subpart B of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2013 CFR

2013-01-01

... by the bank's loan approval mechanism function for a specific loan product is communicated without... details of that offer. (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain...

12 CFR Appendix A to Subpart I of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2013 CFR

2013-01-01

... loan process; or (D) Only the rate approved by the bank's loan approval mechanism function for a... details of that offer. (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain...

12 CFR Appendix A to Subpart I of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2012 CFR

2012-01-01

... loan process; or (D) Only the rate approved by the bank's loan approval mechanism function for a... details of that offer. (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain...

12 CFR Appendix A to Subpart I of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2011 CFR

2011-01-01

... loan process; or (D) Only the rate approved by the bank's loan approval mechanism function for a... details of that offer. (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain...

12 CFR Appendix A to Subpart I of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2014 CFR

2014-01-01

... loan process; or (D) Only the rate approved by the bank's loan approval mechanism function for a... details of that offer. (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain...

Discovery of the hot Big Bang: What happened in 1948

NASA Astrophysics Data System (ADS)

Peebles, Phillip James Edwin

2014-04-01

The idea that the universe is filled with the thermal radiation now termed the Cosmic Microwave Background was discussed in eleven publications in the year 1948. These papers offer a detailed example of the process of development of a new and now very productive line of research, and of the confusion that can attend new ideas. The confusion in this case left a common misunderstanding of the considerations that motivated the idea of the sea of radiation.

Supervisor self-disclosure: balancing the uncontrollable narcissist with the indomitable altruist.

PubMed

Ladany, Nicholas; Walker, Jessica A

2003-05-01

The purpose of this article is to provide supervisors with a framework to determine the effectiveness of self-disclosure in supervision. We posit how self-disclosures can be both memorable to the trainee and facilitative of supervision process and outcome, specifically the supervisory working alliance, trainee disclosure, and trainee edification. Case examples based on the literature and our own personal experiences are offered to illustrate the models' applicability. Copyright 2003 Wiley Periodicals, Inc.

Sports pairs: insights on athletic talent; research reviews: twins with leukemia; parents and twins.

PubMed

Segal, Nancy L

2007-06-01

Twin research exploring genetic and environmental influences on athletic interests and talents is reviewed. Illustrative examples of twin athletes representing a variety of sports activities are presented. This is followed by an overview of twin studies offering critical insights into the onset and progress of leukemia. In the last section, timely events involving twins and parents of twins will be described--each case provides a new look at an old question.

Reforming health care for the elderly--the example of Vorarlberg.

PubMed

Badelt, C

1987-01-01

Vorarlberg--Austria's most western province with a population of about 325,000--has always implemented forms of social policy in which the principles of subsidiarity and solidarity play an important role. This is reflected in the structure of the organizations traditionally providing social services as well as in the more recent programmes the government has developed for social policy. This paper discusses two cases in point: the private associations for home care (Krankenpflegerverbände)--which now exist in 65 Vorarlberg communities and cover 85% of the population in the province--offering nursing services at home to members or to persons who are willing to join the organization when they need care, and the new organizational model, called Gesunder Lebensraum Vorarlberg (GLV), which is successfully operating in a few pilot communities. GLV has spawned umbrella organizations, run by volunteers, and offering a variety of social services relevant to the elderly, for example visiting services or neighbourhood help in case of emergencies. The volunteers get organizational help from a profit-making firm financed by the government. The Vorarlberg models can be interpreted as a step towards demedicalization and deinstitutionalization of health care for the elderly. Nevertheless, they also show the problems that arise when professionals and volunteers must cooperate. The models may lead to savings for the governments involved, although details are still subject to future empirical investigations.

The Lysenko effect: undermining the autonomy of science.

PubMed

Roll-Hansen, Nils

2005-12-01

The "Lysenko affair", which lasted roughly from the mid-1930s to the mid-1960s, was the big scandal of 20th-century science: a classic example of how politics can corrupt and undermine its rational basis. Under Stalin's leadership the Soviet Government suppressed genuine genetics and other sound biology, with devastating consequences for agriculture and health. The worst example of this occurred in August 1948 when the Politburo outlawed the teaching of and research into classical Mendelian genetics. There is broad agreement that this case offers a stark warning against politicians interfering with science. But what, precisely, is this interference that we are being warned about? Whereas the fate of genetics in Soviet Russia was a clear-cut example of direct suppression, there were also other less obvious ways in which politics subverted the scientific process. This indirect interference with science is a persistent feature of modern politics that we need to be on the lookout for.

[Effects of residents' care needs classification (and misclassification) in nursing homes: the example of SOSIA classification].

PubMed

Nebuloni, G; Di Giulio, P; Gregori, D; Sandonà, P; Berchialla, P; Foltran, F; Renga, G

2011-01-01

Since 2003, the Lombardy region has introduced a case-mix reimbursement system for nursing homes based on the SOSIA form which classifies residents into eight classes of frailty. In the present study the agreement between SOSIA classification and other well documented instruments, including Barthel Index, Mini Mental State Examination and Clinical Dementia Rating Scale is evaluated in 100 nursing home residents. Only 50% of residents with severe dementia have been recognized as seriously impaired when assessed with SOSIA form; since misclassification errors underestimate residents' care needs, they determine an insufficient reimbursement limiting nursing home possibility to offer care appropriate for the case-mix.

Migration and Environmental Hazards

PubMed Central

Hunter, Lori M.

2011-01-01

Losses due to natural hazards (e.g., earthquakes, hurricanes) and technological hazards (e.g., nuclear waste facilities, chemical spills) are both on the rise. One response to hazard-related losses is migration, with this paper offering a review of research examining the association between migration and environmental hazards. Using examples from both developed and developing regional contexts, the overview demonstrates that the association between migration and environmental hazards varies by setting, hazard types, and household characteristics. In many cases, however, results demonstrate that environmental factors play a role in shaping migration decisions, particularly among those most vulnerable. Research also suggests that risk perception acts as a mediating factor. Classic migration theory is reviewed to offer a foundation for examination of these associations. PMID:21886366

Wisdom and folly in death and dying.

PubMed

Fitchett, G

1980-09-01

This author presents the argument, in the context of homiletic reflections on Psalm 90∶12, that psychosocial care for the terminally ill continues to be compromised by the anxiety and denial of the staff who provide such care. An illustrative case example is offered. An explanation is provided in terms of the support for such denial in the instrumental values of our technological culture. The work of Kübler-Ross is presented as an example of the religious function of science in modern culture. A paradoxical prescription, based on Psalm 90∶12, is proposed as a solution to the problem. A postscript by a colleague of the author illustrates the subjective attitude of the staff advocated in the paradoxical prescription.

Using Nuclear Medicine Imaging Wisely in Diagnosing Infectious Diseases

PubMed Central

Censullo, Andrea

2017-01-01

Abstract In recent years, there has been an increasing emphasis on efficient and accurate diagnostic testing, exemplified by the American Board of Internal Medicine’s “Choosing Wisely” campaign. Nuclear imaging studies can provide early and accurate diagnoses of many infectious disease syndromes, particularly in complex cases where the differential remains broad. This review paper offers clinicians a rational, evidence-based guide to approaching nuclear medicine tests, using an example case of methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia in a patient with multiple potential sources. Fluorodeoxyglucose-positron emission tomography (FDG-PET) with computed tomography (CT) and sulfur colloid imaging with tagged white blood cell (WBC) scanning offer the most promise in facilitating rapid and accurate diagnoses of endovascular graft infections, vertebral osteomyelitis (V-OM), diabetic foot infections, and prosthetic joint infections (PJIs). However, radiologists at different institutions may have varying degrees of expertise with these modalities. Regardless, infectious disease consultants would benefit from knowing what nuclear medicine tests to order when considering patients with complex infectious disease syndromes. PMID:28480283

Learning With Case-Injected Genetic Algorithms

DTIC Science & Technology

2004-08-01

JSSP ) offers an example of a problem that is suited to an 001 1 L[]1 order-based encoding where where the order of the allelles 010 1 1 matters. Order...8217 t. ýt2 * .tl problem. The next section uses the JSSP to propose and evaluate a solution similarity distance metric for order-based encodings. P1’ P2...P3 . Pn Fig. 7. Individual represents an allocation of platforms to targets. VII. JOB SHOP SCHEDULING ( JSSP ) The JSSP has been well studied elsewhere

Empirical factors and structure transference: Returning to the London account

NASA Astrophysics Data System (ADS)

Bueno, Otávio; French, Steven; Ladyman, James

2012-05-01

We offer a framework to represent the roles of empirical and theoretical factors in theory construction, and examine a case study to illustrate how the framework can be used to illuminate central features of scientific reasoning. The case study provides an extension of French and Ladyman's (1997) analysis of Fritz and Heinz London's model of superconductivity to accommodate the role of the analogy between superconductivity and diamagnetic phenomena in the development of the model between 1935 and 1937. We focus on this case since it allows us to separate the roles of empirical and theoretical factors, and so provides an example of the utility of the approach that we have adopted. We conclude the paper by drawing on the particular framework here developed to address a range of concerns.

Capturing Crime: The Qualitative Analysis of Individual Cases for Advancing Criminological Knowledge.

PubMed

Wright, Kevin A; Bouffard, Leana A

2016-02-01

The qualitative analysis of individual cases has a prominent place in the development of criminological theory, yet progression in the scientific study of crime has largely been viewed as a distinctly quantitative endeavor. In the process, much of the theoretical depth and precision supplied by earlier methods of criminological knowledge production have been sacrificed. The current work argues for a return to our criminological roots by supplementing quantitative analyses with the qualitative inspection of individual cases. We provide a specific example of a literature (i.e., criminal specialization/versatility) that has become increasingly quantitative and could benefit from the use of the proposed approach. We conclude by offering additional areas of research that might be advanced by our framework presented here. © The Author(s) 2014.

Students' Reactions to Climate Change Adaptation Risks and Opportunities

NASA Astrophysics Data System (ADS)

Thiel, M.; Grant, J. H.

2015-12-01

Objectives/Scope How undergraduate (UG) business students at a major public university in the Rocky Mountain region develop appreciation, and some understanding of physical and natural sciences causing climate change (CC) and their implications for society through examples drawn from the students' immediate and meaningful physical environments. Methods, Procedures, Process Three regional examples of ways in which CC impacts the lives of students on the local campus will provide practical approaches for students' environmentally responsible actions beyond the classroom. The cases from different industries will help UG students learn how they play critical roles in preventing and managing natural hazards, disaster management, ecology, development, famine, and secure livelihoods. Observations, Results, Conclusions Classroom discussions of "businesses' ecological responsibilities" in some remote location often fail to "connect" with students who have spent most of their lives within 300 miles of campus. However, when businesses in Asia are adding particulate to the atmosphere in the jet stream over the Pacific, and subsequently graying the local ski slopes, causing early melting and delaying the start of ski seasons, that is a different matter! However, more summer activities offer economic opportunities! A second example is found among the local entrepreneurial woodworkers who take "beetle kill" pine trees that are wildfire hazards and convert them into beautiful, creatively described "blue pine" furniture, interior beams, wall panels and table-top decorations. The "industrial scale" anaerobic digesters used in the "circular economy" of giant cheese factories, dairy farms and packing plants offer a third example for linking business to chemistry, engineering, and aesthetics (odor reduction).

Case study: Mapping tsunami hazards associated with debris flow into a reservoir

USGS Publications Warehouse

Walder, J.S.; Watts, P.; Waythomas, C.F.

2006-01-01

Debris-flow generated impulse waves (tsunamis) pose hazards in lakes, especially those used for hydropower or recreation. We describe a method for assessing tsunami-related hazards for the case in which inundation by coherent water waves, rather than chaotic splashing, is of primary concern. The method involves an experimentally based initial condition (tsunami source) and a Boussinesq model for tsunami propagation and inundation. Model results are used to create hazard maps that offer guidance for emergency planners and responders. An example application explores tsunami hazards associated with potential debris flows entering Baker Lake, a reservoir on the flanks of the Mount Baker volcano in the northwestern United States. ?? 2006 ASCE.

Some life lessons in the work place: personal narrative/case study.

PubMed

Schwartz, Michael A

2014-01-01

Michael Schwartz, a lawyer deaf since birth, describes his journey as a professional for the last 32 years since his graduation from NYU School of Law in 1981. He offers a case study of his experiences with accommodations on the job as required by federal and state law. The study includes specific examples of what worked and what did not work for a deaf lawyer like him working at his craft. Schwartz wraps up with the lessons he learned over the last three decades as we moved from the model of non-compliance to that of compliance, even beyond compliance, with the mandates of law in the employment context.

Three-dimensional solutions of the magnetohydrostatic equations for rigidly rotating magnetospheres in cylindrical coordinates

NASA Astrophysics Data System (ADS)

Wilson, F.; Neukirch, T.

2018-01-01

We present new analytical three-dimensional solutions of the magnetohydrostatic equations, which are applicable to the co-rotating frame of reference outside a rigidly rotating cylindrical body, and have potential applications to planetary magnetospheres and stellar coronae. We consider the case with centrifugal force only, and use a transformation method in which the governing equation for the "pseudo-potential" (from which the magnetic field can be calculated) becomes the Laplace partial differential equation. The new solutions extend the set of previously found solutions to those of a "fractional multipole" nature, and offer wider possibilities for modelling than before. We consider some special cases, and present example solutions.

The costs and benefits of occasional sex: theoretical predictions and a case study.

PubMed

D'Souza, Thomas G; Michiels, Nico K

2010-01-01

Theory predicts that occasional sexual reproduction in predominantly parthenogenetic organisms offers all the advantages of obligate sexuality without paying its full costs. However, empirical examples identifying and evaluating the costs and benefits of rare sex are scarce. After reviewing the theoretical perspective on rare sex, we present our findings of potential costs and benefits of occasional sex in polyploid, sperm-dependent parthenogens of the planarian flatworm Schmidtea polychroa. Despite costs associated with the production of less fertile tetraploids as sexual intermediates, the benefits of rare sex prevail in S. polychroa and may be sufficiently strong to prevent extinction of parthenogenetic populations. This offers an explanation for the dominance of parthenogenesis in S. polychroa. We discuss the enigmatic question why not all organisms show a mixed reproduction mode.

Development of Integrative STEM Curriculum: A Multiple Case Study of Multi-Disciplinary Teams in Two Pennsylvania High Schools

NASA Astrophysics Data System (ADS)

Rider-Bertrand, Joey H.

At the start of the 21st century, STEM education was a new priority in many schools as the focus shifted from separate disciplines to integrative STEM education. Unfortunately, there was limited research to offer guidance to practitioners (Brown, 2012; Honey, Pearson & Schweingruber, 2014). This qualitative, multiple case study explored the experiences of two multi-disciplinary teams of secondary teachers from Pennsylvania who developed and implemented integrative STEM curriculum. Four teachers from a rural high school and four teachers from a suburban high school participated in the study. A document review of integrative STEM curriculum and semi-structured interviews were conducted to learn about the curriculum development process and teachers' perceptions regarding conditions that support or hinder success. Individual and cross-case analyses were performed to establish findings and themes. Although the individual case themes varied slightly, the cross-case themes and assertions that emerged provided highly sought after guidance to practitioners and added to the limited body of research on integrative STEM education. This study found that current curriculum models do not fit integrative STEM curriculum, the development process is fluid, and substantial administrative support and resources are necessary to develop, implement, and sustain integrative STEM education programs. The results offered implications for all educators, as well as two examples of how teachers navigated the terrain of integrative STEM curriculum.

Interface through Cooperative Agreements: Eleven Examples of How It Can Work.

ERIC Educational Resources Information Center

Jellison, Holly M., Ed.

Designed as a resource for community colleges wishing to initiate a cooperative agreement with a local agency to offer community education programs, this publication offers 11 representative examples of such agreements. After explaining that the Center for Community Education collected the agreements as part of a 1981 study of community education…

12 CFR Appendix A to Part 761 - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2013 CFR

2013-01-01

... by the credit union's loan approval mechanism function for a specific loan product is communicated.... (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain.” (1...

12 CFR Appendix A to Part 761 - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2012 CFR

2012-01-01

... by the credit union's loan approval mechanism function for a specific loan product is communicated.... (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain.” (1...

12 CFR Appendix A to Part 1007 - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2013 CFR

2013-01-01

... approved by the covered financial institution's loan approval mechanism function for a specific loan.... (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain.” (1...

12 CFR Appendix A to Part 1007 - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2014 CFR

2014-01-01

... approved by the covered financial institution's loan approval mechanism function for a specific loan.... (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain.” (1...

12 CFR Appendix A to Part 1007 - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2012 CFR

2012-01-01

... approved by the covered financial institution's loan approval mechanism function for a specific loan.... (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain.” (1...

12 CFR Appendix A to Part 761 - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2011 CFR

2011-01-01

... by the credit union's loan approval mechanism function for a specific loan product is communicated.... (c) Offering or negotiating a loan for compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain.” (1...

GO2OGS 1.0: a versatile workflow to integrate complex geological information with fault data into numerical simulation models

NASA Astrophysics Data System (ADS)

Fischer, T.; Naumov, D.; Sattler, S.; Kolditz, O.; Walther, M.

2015-11-01

We offer a versatile workflow to convert geological models built with the ParadigmTM GOCAD© (Geological Object Computer Aided Design) software into the open-source VTU (Visualization Toolkit unstructured grid) format for usage in numerical simulation models. Tackling relevant scientific questions or engineering tasks often involves multidisciplinary approaches. Conversion workflows are needed as a way of communication between the diverse tools of the various disciplines. Our approach offers an open-source, platform-independent, robust, and comprehensible method that is potentially useful for a multitude of environmental studies. With two application examples in the Thuringian Syncline, we show how a heterogeneous geological GOCAD model including multiple layers and faults can be used for numerical groundwater flow modeling, in our case employing the OpenGeoSys open-source numerical toolbox for groundwater flow simulations. The presented workflow offers the chance to incorporate increasingly detailed data, utilizing the growing availability of computational power to simulate numerical models.

See around the corner using active imaging

NASA Astrophysics Data System (ADS)

Steinvall, Ove; Elmqvist, Magnus; Larsson, Håkan

2011-11-01

This paper investigates the prospects of "seeing around the corner" using active imaging. A monostatic active imaging system offers interesting capabilities in the presence of glossy reflecting objects. Examples of such surfaces are windows in buildings and cars, calm water, signs and vehicle surfaces. During daylight it might well be possible to use mirrorlike reflection by the naked eye or a CCD camera for non-line of sight imaging. However the advantage with active imaging is that one controls the illumination. This will not only allow for low light and night utilization but also for use in cases where the sun or other interfering lights limit the non-line of sight imaging possibility. The range resolution obtained by time gating will reduce disturbing direct reflections and allow simultaneous view in several directions using range discrimination. Measurements and theoretical considerations in this report support the idea of using laser to "see around the corner". Examples of images and reflectivity measurements will be presented together with examples of potential system applications.

12 CFR Appendix A to Subpart D of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2014 CFR

2014-01-01

... by the savings association's loan approval mechanism function for a specific loan product is... compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain.” (1) Offering or negotiating terms of a loan for compensation...

12 CFR Appendix A to Subpart D of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2011 CFR

2011-01-01

... by the savings association's loan approval mechanism function for a specific loan product is... compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain.” (1) Offering or negotiating terms of a loan for compensation...

12 CFR Appendix A to Subpart D of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2013 CFR

2013-01-01

... by the savings association's loan approval mechanism function for a specific loan product is... compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain.” (1) Offering or negotiating terms of a loan for compensation...

12 CFR Appendix A to Subpart D of... - Examples of Mortgage Loan Originator Activities

Code of Federal Regulations, 2012 CFR

2012-01-01

... by the savings association's loan approval mechanism function for a specific loan product is... compensation or gain. The following examples illustrate when an employee does or does not offer or negotiate terms of a loan “for compensation or gain.” (1) Offering or negotiating terms of a loan for compensation...

Physical approaches to biomaterial design

PubMed Central

Mitragotri, Samir; Lahann, Joerg

2009-01-01

The development of biomaterials for drug delivery, tissue engineering and medical diagnostics has traditionally been based on new chemistries. However, there is growing recognition that the physical as well as the chemical properties of materials can regulate biological responses. Here, we review this transition with regard to selected physical properties including size, shape, mechanical properties, surface texture and compartmentalization. In each case, we present examples demonstrating the significance of these properties in biology. We also discuss synthesis methods and biological applications for designer biomaterials, which offer unique physical properties. PMID:19096389

Collaborative teaching models for health professionals.

PubMed

Falk-Kessler, Janet; Macrae, Nancy; Dyer, Jean

2005-01-01

Multidisciplinary faculty collaboration within the health professions educational system is explored. The definitions for the concepts of intradisciplinary, multidisciplinary, interdisciplinary and transdisciplinary faculty teams are provided along with the strengths and weaknesses of collaborative teaching and course development across various health profession programs. Examples of these teaching models are described using case studies to illustrate collaborative course development by faculty from Occupational Therapy, Nursing, Physician Assistant, Social Work and Dental Hygiene, Nurse Anesthesia, and Health Services Management programs offered at the University of New England in Portland, Maine, United States of America.

[Care organization at French pediatric emergency department].

PubMed

Gras-Le Guen, Christèle; Vrignaud, Bénédicte; Levieux, Karine

2015-05-01

The number of children admitted to paediatric emergencies is increasing steadily, and is responsible for an altered quality in the patients' reception and some major perturbations in the care organization. In this context, the primary care physicians play a major role in explaining their patients "how to use" the paediatric emergency department (priority in case of vital emergency, periods with lot of admissions and increased waiting time ...). Everything must be done to find an altemative to the pediatric emergency department passage by facilitating communication between caregivers and for example by offering semi urgent consultations possibility.

Enzyme-potentiated desensitization in otolaryngic allergy.

PubMed

Pulec, Jack L

2002-03-01

This is a preliminary report of a new method of treating otolaryngic allergy with enzyme-potentiated desensitization (EPD). The nature of EPD and its use in otolaryngology are described. Thirty-six patients have been treated and followed in a private medical practice since February 1997. This article reviews the clinical features of EPD and provides six cases as examples; the clinical features described include allergic rhinitis, serous otitis media, asthma, dermatitis, fixed food allergy, and Ménière's disease. EPD is an effective technique for the treatment of otolaryngic allergy and offers advantages over conventional techniques.

A cloud-based production system for information and service integration: an internet of things case study on waste electronics

NASA Astrophysics Data System (ADS)

Wang, Xi Vincent; Wang, Lihui

2017-08-01

Cloud computing is the new enabling technology that offers centralised computing, flexible data storage and scalable services. In the manufacturing context, it is possible to utilise the Cloud technology to integrate and provide industrial resources and capabilities in terms of Cloud services. In this paper, a function block-based integration mechanism is developed to connect various types of production resources. A Cloud-based architecture is also deployed to offer a service pool which maintains these resources as production services. The proposed system provides a flexible and integrated information environment for the Cloud-based production system. As a specific type of manufacturing, Waste Electrical and Electronic Equipment (WEEE) remanufacturing experiences difficulties in system integration, information exchange and resource management. In this research, WEEE is selected as the example of Internet of Things to demonstrate how the obstacles and bottlenecks are overcome with the help of Cloud-based informatics approach. In the case studies, the WEEE recycle/recovery capabilities are also integrated and deployed as flexible Cloud services. Supporting mechanisms and technologies are presented and evaluated towards the end of the paper.

48 CFR 25.504 - Evaluation Examples.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Evaluation Examples. 25... PROGRAMS FOREIGN ACQUISITION Evaluating Foreign Offers-Supply Contracts 25.504 Evaluation Examples. The following examples illustrate the application of the evaluation procedures in 25.502 and 25.503. The...

48 CFR 225.504 - Evaluation examples.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 3 2011-10-01 2011-10-01 false Evaluation examples. 225..., DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Evaluating Foreign Offers-Supply Contracts 225.504 Evaluation examples. For examples that illustrate the evaluation procedures in 225.502(c)(ii...

Analysis of methods of processing of expert information by optimization of administrative decisions

NASA Astrophysics Data System (ADS)

Churakov, D. Y.; Tsarkova, E. G.; Marchenko, N. D.; Grechishnikov, E. V.

2018-03-01

In the real operation the measure definition methodology in case of expert estimation of quality and reliability of application-oriented software products is offered. In operation methods of aggregation of expert estimates on the example of a collective choice of an instrumental control projects in case of software development of a special purpose for needs of institutions are described. Results of operation of dialogue decision making support system are given an algorithm of the decision of the task of a choice on the basis of a method of the analysis of hierarchies and also. The developed algorithm can be applied by development of expert systems to the solution of a wide class of the tasks anyway connected to a multicriteria choice.

eHealth Advances in Support of People with Complex Care Needs: Case Examples from Canada, Scotland and the US.

PubMed

Gray, Carolyn Steele; Mercer, Stewart; Palen, Ted; McKinstry, Brian; Hendry, Anne

2016-01-01

Information technology (IT) in healthcare, also referred to as eHealth technologies, may offer a promising solution to the provision of better care and support for people who have multiple conditions and complex care needs, and their caregivers. eHealth technologies can include electronic medical records, telemonitoring systems and web-based portals, and mobile health (mHealth) technologies that enable information sharing between providers, patients, clients and their families. IT often acts as an enabler of improved care delivery, rather than being an intervention per se. But how are different countries seeking to leverage adoption of these technologies to support people who have chronic conditions and complex care needs? This article presents three case examples from Ontario (Canada), Scotland and Kaiser Permanente Colorado (United States) to identify how these jurisdictions are currently using technology to address multimorbidity. A SWOT (strengths, weaknesses, opportunities, threats) analysis is presented for each case and a final discussion addresses the future of eHealth for complex care needs. The case reports presented in this manuscript mark the foundational work of the Multi-National eHealth Research Partnership Supporting Complex Chronic Disease and Disability (the eCCDD Network); a CIHR-funded project intended to support the international development and uptake of eHealth tools for people with complex care needs.

Illustrated Examples of the Effects of Risk Preferences and Expectations on Bargaining Outcomes.

ERIC Educational Resources Information Center

Dickinson, David L.

2003-01-01

Describes bargaining examples that use expected utility theory. Provides example results that are intuitive, shown graphically and algebraically, and offer upper-level student samples that illustrate the usefulness of the expected utility theory. (JEH)

Passive solar design strategies: Remodeling guidelines for conserving energy at home

NASA Astrophysics Data System (ADS)

The idea of passive solar is simple, but applying it effectively does require information and attention to the details of design and construction. Some passive solar techniques are modest and low-cost, and require only small changes in remodeler's typical practice. At the other end of the spectrum, some passive solar systems can almost eliminate a house's need for purchased heating (and in some cases, cooling) energy - but probably at a relatively high first cost. In between are a broad range of energy-conserving passive solar techniques. Whether or not they are cost-effective, practical, and attractive enough to offer a market advantage to any individual remodeler depends on very specific factors such as local costs, climate, and market characteristics. Passive Solar Design Strategies: Remodeling Guidelines For Conserving Energy At Home is written to help give remodelers the information they need to make these decisions. Passive Solar Design Strategies is a package in three basic parts: the guidelines contain information about passive solar techniques and how they work, and provides specific examples of systems which will save various percentages of energy; the worksheets offer a simple, fill-in-the-blank method to pre-evaluate the performance of a specific design; and the worked example demonstrates how to complete the worksheets for a typical residence.

Diseases in marine invertebrates associated with mariculture and commercial fisheries

NASA Astrophysics Data System (ADS)

Sweet, Michael J.; Bateman, Kelly S.

2015-10-01

Diseases in marine invertebrates are increasing in both frequency and intensity around the globe. Diseases in individuals which offer some commercial value are often well documented and subsequently well studied in comparison to those wild groups offering little commercial gain. This is particularly the case with those associated with mariculture or the commercial fisheries. Specifically, these include many Holothuroidea, and numerous crustacea and mollusca species. Pathogens/parasites consisting of both prokaryotes and eukaryotes from all groups have been associated with diseases from such organisms, including bacteria, viruses, fungi and protozoa. Viral pathogens in particular, appear to be an increasingly important group and research into this group will likely highlight a larger number of diseases and pathogens being described in the near future. Interestingly, although there are countless examples of the spread of disease usually associated with transportation of specific infected hosts for development of aquaculture practices, this process appears to be continuing with no real sign of effective management and mitigation strategies being implicated. Notably, even in well developed countries such as the UK and the US, even though live animal trade may be well managed, the transport of frozen food appears to be less well so and as evidence suggests, even these to have the potential to transmit pathogens when used as a food source for example.

Reprint of 'Diseases in marine invertebrates associated with mariculture and commercial fisheries'

NASA Astrophysics Data System (ADS)

Sweet, Michael J.; Bateman, Kelly S.

2016-07-01

Diseases in marine invertebrates are increasing in both frequency and intensity around the globe. Diseases in individuals which offer some commercial value are often well documented and subsequently well studied in comparison to those wild groups offering little commercial gain. This is particularly the case with those associated with mariculture or the commercial fisheries. Specifically, these include many Holothuroidea, and numerous crustacea and mollusca species. Pathogens/parasites consisting of both prokaryotes and eukaryotes from all groups have been associated with diseases from such organisms, including bacteria, viruses, fungi and protozoa. Viral pathogens in particular, appear to be an increasingly important group and research into this group will likely highlight a larger number of diseases and pathogens being described in the near future. Interestingly, although there are countless examples of the spread of disease usually associated with transportation of specific infected hosts for development of aquaculture practices, this process appears to be continuing with no real sign of effective management and mitigation strategies being implicated. Notably, even in well developed countries such as the UK and the US, even though live animal trade may be well managed, the transport of frozen food appears to be less well so and as evidence suggests, even these to have the potential to transmit pathogens when used as a food source for example.

U.N. official urges business to support HIV prevention.

PubMed

1997-02-21

Executive Director Peter Piot of the Joint United Nations Programme on HIV/AIDS called on companies to initiate aggressive measures to prevent the further spread of HIV. The global total of HIV cases reached 23 million in 1996. The epidemic threatens the growth of the global economy, particularly in developing nations where private corporations are seeking new markets. The economic toll due to AIDS is devastating because it affects young people who are at the height of their earning power. Piot offered examples of prevention initiatives that have been undertaken by companies to control the epidemic.

Evaluation of the Child with Short Stature.

PubMed

Mehlman, Charles T; Ain, Michael C

2015-10-01

Orthopedic surgeons frequently encounter short statured patients. A systematic approach is needed for proper evaluation of these children. The differential diagnosis includes both proportionate and disproportionate short stature types. A proper history and physical examination and judicious use of plain film radiography will establish the diagnosis in most cases. In addition to the orthopedic surgeon, most of these patients will also be evaluated by other specialists, including endocrinologists and geneticists. This article provides an overview of the evaluation of the child with short stature and offers several illustrative examples. Copyright © 2015 Elsevier Inc. All rights reserved.

Quantification of uncertainties for application in detonation simulation

NASA Astrophysics Data System (ADS)

Zheng, Miao; Ma, Zhibo

2016-06-01

Numerical simulation has become an important means in designing detonation systems, and the quantification of its uncertainty is also necessary to reliability certification. As to quantifying the uncertainty, it is the most important to analyze how the uncertainties occur and develop, and how the simulations develop from benchmark models to new models. Based on the practical needs of engineering and the technology of verification & validation, a framework of QU(quantification of uncertainty) is brought forward in the case that simulation is used on detonation system for scientific prediction. An example is offered to describe the general idea of quantification of simulation uncertainties.

Characterization of Nighttime Light Variability Over the Southeastern United States

NASA Technical Reports Server (NTRS)

Cole, Tony A.; Molthan, Andrew L.; Schultz, Lori A.

2016-01-01

City lights provide indications of human activity at night. Nighttime satellite imagery offers daily snapshots of this activity. With calibrated, science-quality imagery, long-term monitoring can also be achieved. The degree to which city lights fluctuate, however, is not well known. For the application of detecting power outages, this degree of variability is crucial for assessing reductions to city lights based on historical trends. Eight southeastern U.S. cities are analyzed to understand the relationship between emission variability and several population centers. A preliminary, example case power outage study is also discussed as a transition into future work.

Telepsychotherapy and the Therapeutic Relationship: Principles, Advantages, and Case Examples.

PubMed

Kocsis, Barbara J; Yellowlees, Peter

2018-05-01

As the use of technology continues to expand within our mental healthcare system, there has been an increasing interest in conducting psychotherapy online using videoconferencing. Literature pertaining to telepsychotherapy has explored possible drawbacks of this modality on the therapeutic relationship, although several studies have shown that the efficacy of online psychotherapy is equivalent to in-person approaches. Little is written about the potential advantages to the psychotherapeutic relationship when psychotherapy is carried out over videoconferencing. The available literature was reviewed, as were the general principles of telepsychotherapy and the therapeutic relationship, followed by a more in-depth consideration of patient populations for whom telepsychotherapy may offer distinct advantages. The current literature, as well as our own clinical experience, suggests that telepsychotherapy may be effective for a broad range of patients, and it may offer distinct advantages in the building of a trusting psychotherapeutic relationship. Telepsychotherapy offers a novel way to reach and form strong psychotherapeutic relationships with many different types of patients, and it may foster therapeutic intimacy in ways that in-person psychotherapy cannot. More research is needed to further explore this unique modality.

A history of nursing: a history of caring?

PubMed

Maggs, C

1996-03-01

The history of nursing is, itself, a fit subject for research. It is unclear what would constitute history in this case, its time frame or its methodology. It is also the case that the purpose of history needs exploration, since it can meet many goals, including the goal of professionalization. This paper explores these issues in some detail, using examples from the literature in the history of nursing. It explores historical inquiry and purpose and the problems of sources. The paper also addresses the relationship between the history of nursing and nursing theory and questions whether existing historical scholarship is integrated with or is outwith mainstream nursing theory. The paper questions the relevance of the history of nursing and suggests that the history of caring may offer one way through history to nursing theory.

Political Impetus: Towards a Successful Agenda-Setting for Inclusive Health Policies in Low- and Middle-Income Countries Comment on "Shaping the Health Policy Agenda: The Case of Safe Motherhood Policy in Vietnam".

PubMed

Yang, Xiaoguang; Qian, Xu

2016-02-04

Agenda-setting is a crucial step for inclusive health policies in the low- and middle-income countries (LMICs). Enlightened by Ha et al manuscript, this commentary paper argues that 'political impetus' is the key to the successful agenda-setting of health policies in LMICs, though other determinants may also play the role during the process. This Vietnamese case study presents a good example for policy-makers of other LMICs; it offers insights for contexts where there are limited health resources and poor health performance. Further research which compares various stages of the health policy process across countries, is much needed. © 2016 by Kerman University of Medical Sciences.

Ten tools of continuous quality improvement: a review and case example of hospital discharge.

PubMed

Ziegenfuss, J T; McKenna, C K

1995-01-01

Concepts and methods of continuous quality improvement have been endorsed by quality specialists in American Health care, and their use has convinced CEOs that industrial methods can make a contribution to health and medical care. For all the quality improvement publications, there are still few that offer a clear, concise definition and an explanation of the primary tools for teaching purposes. This report reviews ten continuous quality improvement methods including: problem solving cycle, affinity diagrams, cause and effect diagrams, Pareto diagrams, histograms, bar charts, control charts, scatter diagrams, checklists, and a process decision program chart. These do not represent an exhaustive list, but a set of commonly used tools. They are applied to a case study of bed utilization in a university hospital.

Time-dependent landslide probability mapping

USGS Publications Warehouse

Campbell, Russell H.; Bernknopf, Richard L.; ,

1993-01-01

Case studies where time of failure is known for rainfall-triggered debris flows can be used to estimate the parameters of a hazard model in which the probability of failure is a function of time. As an example, a time-dependent function for the conditional probability of a soil slip is estimated from independent variables representing hillside morphology, approximations of material properties, and the duration and rate of rainfall. If probabilities are calculated in a GIS (geomorphic information system ) environment, the spatial distribution of the result for any given hour can be displayed on a map. Although the probability levels in this example are uncalibrated, the method offers a potential for evaluating different physical models and different earth-science variables by comparing the map distribution of predicted probabilities with inventory maps for different areas and different storms. If linked with spatial and temporal socio-economic variables, this method could be used for short-term risk assessment.

Piecewise polynomial representations of genomic tracks.

PubMed

Tarabichi, Maxime; Detours, Vincent; Konopka, Tomasz

2012-01-01

Genomic data from micro-array and sequencing projects consist of associations of measured values to chromosomal coordinates. These associations can be thought of as functions in one dimension and can thus be stored, analyzed, and interpreted as piecewise-polynomial curves. We present a general framework for building piecewise polynomial representations of genome-scale signals and illustrate some of its applications via examples. We show that piecewise constant segmentation, a typical step in copy-number analyses, can be carried out within this framework for both array and (DNA) sequencing data offering advantages over existing methods in each case. Higher-order polynomial curves can be used, for example, to detect trends and/or discontinuities in transcription levels from RNA-seq data. We give a concrete application of piecewise linear functions to diagnose and quantify alignment quality at exon borders (splice sites). Our software (source and object code) for building piecewise polynomial models is available at http://sourceforge.net/projects/locsmoc/.

Balancing the Budget through Social Exploitation: Why Hard Times Are Even Harder for Some.

PubMed

Tropman, John; Nicklett, Emily

2012-01-01

In all societies needs and wants regularly exceed resources. Thus societies are always in deficit; demand always exceeds supply and "balancing the budget" is a constant social problem. To make matters somewhat worse, research suggests that need- and want-fulfillment tends to further stimulate the cycle of wantseeking rather than satiating desire. Societies use various resource-allocation mechanisms, including price, to cope with gaps between wants and resources. Social exploitation is a second mechanism, securing labor from population segments that can be coerced or convinced to perform necessary work for free or at below-market compensation. Using practical examples, this article develops a theoretical framework for understanding social exploitation. It then offers case examples of how different segments of the population emerge as exploited groups in the United States, due to changes in social policies. These exploitative processes have been exacerbated and accelerated by the economic downturn that began in 2007.

Individuals' decisions affecting radiation exposure after a nuclear explosion.

PubMed

Florig, H Keith; Fischhoff, Baruch

2007-05-01

In the aftermath of a nuclear attack, shelters can offer potentially important protection. How well they fill that role depends on a set of interdependent decisions made by the individuals and organizations that must prepare and use them. We look at three such decisions. For each, we begin with formal analysis of the consequences expected from different possible actions. Those analyses are, then, reviewed in terms of how individuals facing these choices will perceive them, given the information that they are likely to have. The first example suggests that preparing a home shelter according to guidelines from the Department of Homeland Security may not pass a cost-benefit test. The second example explores the use of readily available information about a blast to infer how urgently shelter should be sought. The third example considers when shelters should be left, suggesting that individuals with the best shelters and slowest evacuation speeds should evacuate last, if they have the provisions needed to remain. In each case, helping people to protect themselves requires prior risk analyses and communication development.

Misinformation in eating disorder communications: Implications for science communication policy

NASA Astrophysics Data System (ADS)

Radford, Benjamin

Though eating disorders are a serious public health threat, misinformation about these potentially deadly diseases is widespread. This study examines eating disorder information from a wide variety of sources including medical journals, news reports, and popular social activist authors. Examples of misinformation were identified, and three aspects of eating disorders (prevalence, mortality, and etiology) were chosen as key indicators of scientific illiteracy about those illnesses. A case study approach was then adopted to trace examples of misinformation to their original sources whenever possible. A dozen examples include best-selling books, national eating disorder information clearinghouses; the news media; documentary feature films; and a PBS television Nova documentary program. The results provide an overview of the ways in which valid information becomes flawed, including poor journalism, lack of fact-checking, plagiarism, and typographical errors. Less obvious---and perhaps even more important---much of the misinformation results from scientific research being co-opted to promote specific sociopolitical agendas. These results highlight a significant gap in science communication between researchers, the medical community, and the public regarding these diseases, and recommendations to address the problem are offered.

Who's Looking? Examining the Role of Gender and Rank in Faculty Outside Offers

ERIC Educational Resources Information Center

O'Meara, KerryAnn; Fink, John; White-Lewis, Damani Khary

2017-01-01

Outside offers, defined as comparable offers of employment at another organization, are means by which faculty determine their relative market worth and increase their salary at their home institution. Despite the career advantages associated with outside offers, little is known about the groups of faculty most likely to receive them. For example,…

Realizing good care within a context of cross-cultural diversity: an ethical guideline for healthcare organizations in Flanders, Belgium.

PubMed

Denier, Yvonne; Gastmans, Chris

2013-09-01

In our globalizing world, health care professionals and organizations increasingly experience cross-cultural challenges in care relationships, which give rise to ethical questions regarding "the right thing to do" in such situations. For the time being, the international literature lacks examples of elaborated ethical guidelines for cross-cultural healthcare on the organizational level. As such, the ethical responsibility of healthcare organizations in realizing cross-cultural care remains underexposed. This paper aims to fill this gap by offering a case-study that illustrates the bioethical practice on a large-scale organizational level by presenting the ethical guideline developed in the period 2007-2011 by the Ethics Committee of Zorgnet Vlaanderen, a Christian-inspired umbrella organization for over 500 social profit healthcare organizations in Flanders, Belgium. The guideline offers an ethical framework within which fundamental ethical values are being analyzed within the context of cross-cultural care. The case study concludes with implications for healthcare practice on four different levels: (1) the level of the healthcare organization, (2) staff, (3) care receivers, and (4) the level of care supply. The study combines content-based ethics with process-based benchmarks. Copyright © 2013. Published by Elsevier Ltd.

Schematic representation of case study research designs.

PubMed

Rosenberg, John P; Yates, Patsy M

2007-11-01

The paper is a report of a study to demonstrate how the use of schematics can provide procedural clarity and promote rigour in the conduct of case study research. Case study research is a methodologically flexible approach to research design that focuses on a particular case - whether an individual, a collective or a phenomenon of interest. It is known as the 'study of the particular' for its thorough investigation of particular, real-life situations and is gaining increased attention in nursing and social research. However, the methodological flexibility it offers can leave the novice researcher uncertain of suitable procedural steps required to ensure methodological rigour. This article provides a real example of a case study research design that utilizes schematic representation drawn from a doctoral study of the integration of health promotion principles and practices into a palliative care organization. The issues discussed are: (1) the definition and application of case study research design; (2) the application of schematics in research; (3) the procedural steps and their contribution to the maintenance of rigour; and (4) the benefits and risks of schematics in case study research. The inclusion of visual representations of design with accompanying explanatory text is recommended in reporting case study research methods.

Post-deployment Multi-symptom Disorder rehabilitation: An integrated approach to rehabilitation.

PubMed

Bosco, Michelle A; Murphy, Jennifer; Peters, Walter E; Clark, Michael E

2015-01-01

Veterans and active duty service members returning from Operation New Dawn and those having returned from Operations Iraqi and Enduring Freedom frequently report the presence of overlapping, co-morbid symptom clusters consisting of chronic pain, mild cognitive complaints, and posttraumatic stress symptoms/disorder or mood disturbance. This presentation has been called Post-deployment Multi-symptom Disorder (PMD) and its implications not only impact various functional domains, but have also influenced a system/continuum of care to rise to meet the challenges of treating PMD. This continuum is based on innovation informed by evidence-based therapies, systemic limitations, and a focus on functional improvement rather than diagnostic classification. The purpose of this paper is to describe the symptomatic, functional and systemic challenges inherent to PMD conceptualization and treatment. The constituent clusters of PMD are defined and exemplified, its functional impact is illustrated, and a continuum of care at a large southeastern Veterans Affairs (VA) hospital offering an interdisciplinary approach to integrated rehabilitation is described. Three case examples are provided that that underscore the importance of vocation for improved behavioral health and quality of life. The case examples demonstrate how vocational rehabilitation services are an integral component of PMD treatment.}

Posttraumatic stress disorder in tort actions: forensic minefield.

PubMed

Sparr, L F; Boehnlein, J K

1990-01-01

The authors discuss posttraumatic stress disorder (PTSD) as a basis for personal injury litigation. Three case examples raise issues related to: (1) the controversy surrounding expansion of tort liability, (2) the courtroom use of psychiatric nomenclature as represented in the DSM (e.g., PTSD), and (3) ethical concerns regarding psychiatric expert witnesses. Psychiatrists became easy targets when problems related to personal injury "stress" cases developed. A careful analysis, however, demonstrates that the issues are complex and multifaceted. For example, tort liability expansion was primarily instituted to compel a greater provision of liability insurance, not to reward stress claims. The increasing use of psychiatry's DSM in the courtroom has occurred despite explicit precautions against forensic application. Finally, the need for psychiatric expert witnesses has increased because courts have gradually usurped some psychiatric clinical prerogatives and because there has been a trend toward greater consideration of emotional pain and suffering. Although psychiatric expert witnesses have not been beyond reproach, critics have attempted to impeach the entire psychiatric profession for the questionable actions of the minority. The authors provide a detailed analysis of current problems, offer suggestions for improvement, and provide an educational counterpoint to the "hysterical invective" that often greets psychiatric testimony.

Assessing formal teaching of ethics in physiology: an empirical survey, patterns, and recommendations.

PubMed

Goswami, Nandu; Batzel, Jerry Joseph; Hinghofer-Szalkay, Helmut

2012-09-01

Ethics should be an important component of physiological education. In this report, we examined to what extent teaching of ethics is formally being incorporated into the physiology curriculum. We carried out an e-mail survey in which we asked the e-mail recipients whether their institution offered a course or lecture on ethics as part of the physiology teaching process at their institution, using the following query: "We are now doing an online survey in which we would like to know whether you offer a course or a lecture on ethics as part of your physiology teaching curriculum." The response rate was 53.3%: we received 104 responses of a total of 195 sent out. Our responses came from 45 countries. While all of our responders confirmed that there was a need for ethics during medical education and scientific training, the degree of inclusion of formal ethics in the physiology curriculum varied widely. Our survey showed that, in most cases (69%), including at our Medical University of Graz, ethics in physiology is not incorporated into the physiology curriculum. Given this result, we suggest specific topics related to ethics and ethical considerations that could be integrated into the physiology curriculum. We present here a template example of a lecture "Teaching Ethics in Physiology" (structure, content, examples, and references), which was based on guidelines and case reports provided by experts in this area (e.g., Benos DJ. Ethics revisited. Adv Physiol Educ 25: 189-190, 2001). This lecture, which we are presently using in Graz, could be used as a base that could lead to greater awareness of important ethical issues in students at an early point in the educational process.

Into the development of a model to assess beam shaping and polarization control effects on laser cutting

NASA Astrophysics Data System (ADS)

Rodrigues, Gonçalo C.; Duflou, Joost R.

2018-02-01

This paper offers an in-depth look into beam shaping and polarization control as two of the most promising techniques for improving industrial laser cutting of metal sheets. An assessment model is developed for the study of such effects. It is built upon several modifications to models as available in literature in order to evaluate the potential of a wide range of considered concepts. This includes different kinds of beam shaping (achieved by extra-cavity optical elements or asymmetric diode staking) and polarization control techniques (linear, cross, radial, azimuthal). A fully mathematical description and solution procedure are provided. Three case studies for direct diode lasers follow, containing both experimental data and parametric studies. In the first case study, linear polarization is analyzed for any given angle between the cutting direction and the electrical field. In the second case several polarization strategies are compared for similar cut conditions, evaluating, for example, the minimum number of spatial divisions of a segmented polarized laser beam to achieve a target performance. A novel strategy, based on a 12-division linear-to-radial polarization converter with an axis misalignment and capable of improving cutting efficiency with more than 60%, is proposed. The last case study reveals different insights in beam shaping techniques, with an example of a beam shape optimization path for a 30% improvement in cutting efficiency. The proposed techniques are not limited to this type of laser source, neither is the model dedicated to these specific case studies. Limitations of the model and opportunities are further discussed.

Two-dimensional assemblies of soft repulsive colloids confined at fluid interfaces

NASA Astrophysics Data System (ADS)

Isa, L.; Buttinoni, I.; Fernandez-Rodriguez, M. A.; Vasudevan, S. A.

2017-07-01

Colloidal systems are an excellent example of a materials class for which interrogating fundamental questions leads to answers of direct applied relevance. In our group, we in particular focus on two-dimensional assemblies of micro- and nano-particles confined at the interface between two fluids, e.g., oil-water. Here, we review our work on systems interacting through soft repulsive forces of different origin, i.e., electrostatic and steric. By starting from the paradigmatic case of charged colloids at an interface, we show how they are both offering great opportunities as model systems to investigate the structural and mechanical response of materials and as versatile patterning tools for surface nanostructuring. We then move to the case of deformable particles interacting via steric contacts. We first examine microgel particles, which we also demonstrate as very promising models for structural investigations and robust elements for tunable nanolithography. We conclude by briefly discussing the case of particles comprising a hard inorganic core and a deformable polymer shell, which maintain some of the advantageous features of microgel particles, but also enable the realization of two-dimensional functional materials. This article offers our perspective on a very active field of research, where many interesting developments are expected in the near future. Contribution to the Focus Issue Self-assemblies of Inorganic and Organic Nanomaterials edited by Marie-Paule Pileni.

Interprofessional anatomy education in the United Kingdom and Ireland: Perspectives from students and teachers.

PubMed

Smith, Claire F; Hall, Samuel; Border, Scott; Adds, Philip J; Finn, Gabrielle M

2015-01-01

There is increasing recognition of multiprofessional learning in anatomy and its role in medical and healthcare professions. This study utilized two components to investigate anatomy interprofessional education (AIPE) in the United Kingdom and Ireland. First, a survey involving qualitative and quantitative components asked Heads of Anatomy to report on their institutions' uptake of AIPE. Second, a series of case studies explored the experiences of students by using evaluation forms and an in-depth analysis of thematic concepts to understand the learners' perspectives on designing and delivering AIPE. Out of the 13 institutions that took part in the survey, eight did not offer an AIPE program. Between the remaining five institutions that deliver AIPE programs, 10 different modules are offered with the majority involving healthcare professions. The AIPE component is rated highly by students. The themes from the case studies highlight how valuable AIPE is from the student perspective both in terms of engaging them in anatomy as well as in the broader skills of teamwork and communication. The case studies also revealed how AIPE can be engaging for groups of students who might not have previously had access to cadaveric anatomy, for example, engineers and archeologists. The results of this study have implications for curriculum design in medicine and healthcare but also for further engagement of professional groups from non-healthcare backgrounds. © 2015 American Association of Anatomists.

MID-LATITUDE CYCLONES WITH TROPICAL ORIGINS: lessons from two historical case studies.

NASA Astrophysics Data System (ADS)

García-Herrera, R.; Vaquero, J. M.; Wheeler, D.

2009-04-01

Interest in storm and hurricane activity has grown over recent years, their changing incidence being seen, rightly or wrongly, as a gauge of ‘global warming'. Yet such judgements can be confidently offered only on the basis of a reliable long period of record that provides more informative perspective on the events of the past few decades. This presentation is concerned with two examples of hurricane activity, both of which make valuable use of historical source material but provide different lessons for climatologists. The first example is from 1680 and demonstrates the value of historical source material in reconstructing events from the distant past and suggests a way forward in developing and improving the long-term storm chronologies. The other, based on the analogous events of 1842 and 2005, offers a convincing demonstration of the need to call upon such comprehensive long-term chronologies in order to avoid making mistaken and unintentionally ill-informed observations on the seeming idiosyncrasies of recent climatic variation. The first example, from August 1680, reconstructs the trajectory and development of an Atlantic tropical cyclone, and draws upon a notable variety of documentary sources ranging from ships' logbooks, official and unofficial correspondence and some early examples of instrumental data. It serves as a model of how such sources, which remain largely unexploited, can be called upon to provide important climatic information. It allows also for the reconstruction the tropical and extratropical phases of the cyclone's trajectory and its possible impact over the UK. The second example, which compares hurricane Vince (2005) with an earlier but overlooked analogue from 1842, demonstrates the caution with which recent events should be interpreted and the need to take as long-term view as possible. Hurricane Vince, which moved directly from the eastern Atlantic towards Iberia, was widely proclaimed as a unique event and a consequence of global warming. Yet a careful search of the historical record provided an almost perfect analogue from 1842 and in doing so offered a salutary warning of our need for caution and for a clearer picture of the past. This presentation reviews both examples and discusses their implications in terms of the possibility of improving the cyclone chronology and, thereby, of assisting in our understanding of present-day events. References Vaquero J.M., R. García-Herrera, D. Wheeler, M. Chenoweth and C. J. Mock, 2008: An historical analogue of 2005 hurricane Vince. Bulletin of the American Meteorological Society, 89, 191 - 201. WheelerD., R. García-Herrera, J.M.Vaquero, M. Chenoweth and C. J. Mock, 2009: Reconstructing the trajectory of the August 1680 Hurricane from contemporary records Bulletin of the American Meteorological Society,(accepted).

Role of prospective registries in defining the value and effectiveness of spine care.

PubMed

McGirt, Matthew J; Parker, Scott L; Asher, Anthony L; Norvell, Dan; Sherry, Ned; Devin, Clinton J

2014-10-15

Literature review and case example. Describe methodological considerations of spine surgery registries. Review existing spine surgery registries. Describe the Vanderbilt Prospective Spine Registry (VPSR) as a case example and demonstrate its impact on comparative effectiveness research, value analysis, quality improvement, and practice-based learning. To bend the cost curve and ultimately achieve sustainability in health care, medical providers and surgical treatments of the highest quality and effectiveness must be preferentially used and purchased. As the current US health care environment continues to evolve, it will be essential for all spine clinicians to understand and be facile with the principles of evidence-based health care reform. We describe the methodological considerations of spine surgery registries, review the literature to describe existing spine surgery registries, and discuss the VPSR as a case example. We were able to obtain detailed information on 13 existing spine surgery registries through various internet-based resources. Of the 13, 2 registries had start dates before 2000, 3 between 2001 and 2005, 5 starting in 2006, and 3 were indeterminate. Follow-up rates were in the range from 22% to 79%, with longer follow-up times consistently producing lower follow-up rates. Prospective, longitudinal, patient-reported outcomes registries are powerful tools that allow measurement of cost, safety, effectiveness, and health care value across clinically meaningful episodes of care. Registries entirely based on claims or billing data, safety measures alone, process measures, or other proxies of outcome offer valuable insights, but do not provide comprehensive data to drive patient-centered value-based reform. As more spine-focused registries emerge and their integration into the US health care delivery evolve, the evidence to power value-based reform will be enabled.

AstroFest: A Case Study of an Astronomy Outreach Program at Penn State University

NASA Astrophysics Data System (ADS)

Palma, C.; Charlton, J. C.

2003-12-01

The Pennsylvania State University Department of Astronomy & Astrophysics has developed a multi-faceted approach to outreach in astronomy. Our programs include In-Service Workshops in Astronomy for middle-school and high-school science teachers, planetarium shows for local elementary school classes, and a series of sponsored, popular level talks, for example. One of our most popular outreach events is called ``AstroFest"; this is a four night festival of astronomy that we hold concurrently with the Central Pennsylvania Festival of the Arts (``ArtsFest"). The AstroFest program was devised by undergraduate students during the summer of 1999, and we continue to hold it annually. Each night of the event, we offer talks at a popular level on subjects such as black holes, life on Mars, and the world's largest telescopes. Throughout the night we also offer planetarium shows, a chance to use our rooftop telescopes, a question & answer table with prizes, kids' activities that include launching bubble rockets, and a number of other demonstrations and tours. In this poster, I present the full complement of astronomy outreach programs offered by Penn State, and I focus in particular on AstroFest as a case study that highlights the challenges we face and the positive outcomes we have realized. Funding for our outreach program has come from several sources, including NASA E/PO supplement grants, the STScI IDEAS program, The Pennsylvania Space Grant Consortium, and the Pennsylvania State University Eberly College of Science.

The impact of health-care service guarantees on consumer decision-making: an experimental investigation.

PubMed

Kennett-Hensel, Pamela A; Min, Kyeong Sam; Totten, Jeff W

2012-01-01

While examples of the successful use of service guarantees in health-care do exist, to-date, researchers have yet to examine this industry-specific application beyond a case study perspective. The results of this experiment begin to shed light on whether or not guarantees should be used, and if so, under what conditions are they appropriate. Respondents indicate that the thoughtful use of service guarantees can positively impact their perceptions of the health-care provider's reputation and, ultimately, their behavioral intentions towards the same provider. However, consideration must be given to the type of guarantee being offered and to whom the guarantee is targeted.

Preliminary Work Domain Analysis for Human Extravehicular Activity

NASA Technical Reports Server (NTRS)

McGuire, Kerry; Miller, Matthew; Feigh, Karen

2015-01-01

A work domain analysis (WDA) of human extravehicular activity (EVA) is presented in this study. A formative methodology such as Cognitive Work Analysis (CWA) offers a new perspective to the knowledge gained from the past 50 years of living and working in space for the development of future EVA support systems. EVA is a vital component of human spaceflight and provides a case study example of applying a work domain analysis (WDA) to a complex sociotechnical system. The WDA presented here illustrates how the physical characteristics of the environment, hardware, and life support systems of the domain guide the potential avenues and functional needs of future EVA decision support system development.

Policy Perspective: Ensuring Comprehensive Care and Support for Gender Nonconforming Children and Adolescents

PubMed Central

Dowshen, Nadia; Meadows, Rachel; Byrnes, Maureen; Hawkins, Linda; Eder, Jennifer; Noonan, Kathleen

2016-01-01

Abstract Despite recent notable advances in societal equality for lesbian, gay, bisexual, and transgender (LGBT) individuals, youth who identify as trans* or gender nonconforming, in particular, continue to experience significant challenges accessing the services they need to grow into healthy adults. This policy perspective first offers background information describing this population, their unique healthcare needs, and obstacles when seeking care, including case study examples. The authors then provide recommendations for medical education, health systems, and insurance payers, as well as recommendations for school systems and broader public policy changes to improve the health and well-being of gender nonconforming youth. PMID:28861528

Astronomy 3.0 Style

NASA Astrophysics Data System (ADS)

Accomazzi, A.

2010-10-01

Over the next decade, we will witness the development of a new infrastructure in support of data-intensive scientific research, which includes Astronomy. This new networked environment will offer both challenges and opportunities to our community and has the potential to transform the way data are described, curated and preserved. Based on the lessons learned during the development and management of the ADS, a case is made for adopting the emerging technologies and practices of the Semantic Web to support the way Astronomy research will be conducted. Examples of how small, incremental steps can, in the aggregate, make a significant difference in the provision and repurposing of astronomical data are provided.

Neyman, Markov processes and survival analysis.

PubMed

Yang, Grace

2013-07-01

J. Neyman used stochastic processes extensively in his applied work. One example is the Fix and Neyman (F-N) competing risks model (1951) that uses finite homogeneous Markov processes to analyse clinical trials with breast cancer patients. We revisit the F-N model, and compare it with the Kaplan-Meier (K-M) formulation for right censored data. The comparison offers a way to generalize the K-M formulation to include risks of recovery and relapses in the calculation of a patient's survival probability. The generalization is to extend the F-N model to a nonhomogeneous Markov process. Closed-form solutions of the survival probability are available in special cases of the nonhomogeneous processes, like the popular multiple decrement model (including the K-M model) and Chiang's staging model, but these models do not consider recovery and relapses while the F-N model does. An analysis of sero-epidemiology current status data with recurrent events is illustrated. Fix and Neyman used Neyman's RBAN (regular best asymptotic normal) estimates for the risks, and provided a numerical example showing the importance of considering both the survival probability and the length of time of a patient living a normal life in the evaluation of clinical trials. The said extension would result in a complicated model and it is unlikely to find analytical closed-form solutions for survival analysis. With ever increasing computing power, numerical methods offer a viable way of investigating the problem.

Energy and Environment Guide to Action - Chapter 4.5: Lead by Example

EPA Pesticide Factsheets

Provides recommendations on designing, implementing, and evaluating lead by example programs, which offer states opportunities to achieve substantial energy cost savings within their operations. State success stories are included for reference.

More examples of chimpanzees teaching.

PubMed

Scheel, Matthew H; Shaw, Heidi L; Gardner, R Allen

2015-01-01

Darwinism is a principle of biological continuity. This commentary argues against any claim of discontinuity between humans and other animals that must be based on absence of evidence. Instead, we offer additional examples of active teaching by chimpanzees.

Trans-kingdom small RNA transfer during host-pathogen interactions: The case of P. falciparum and erythrocytes.

PubMed

Walzer, Katelyn A; Chi, Jen-Tsan

2017-04-03

This review focuses on the role of trans-kingdom movement of small RNA (sRNA) molecules between parasites, particularly Plasmodium falciparum, and their respective host cells. While the intercellular transfer of sRNAs within organisms is well recognized, recent studies illustrate many examples of trans-kingdom sRNA exchange within the context of host-parasite interactions. These interactions are predominantly found in the transfer of host sRNAs between erythrocytes and the invading P. falciparum, as well as other host cell types. In addition, parasite-encoded sRNAs can also be transferred to host cells to evade the immune system. The transport of these parasite sRNAs in the body fluids of the host may also offer means to detect and monitor the parasite infection. These isolated examples may only represent the tip of the iceberg in which the transfer of sRNA between host and parasites is a critical aspect of host-pathogen interactions. In addition, the levels of these sRNAs and their speed of transfer may vary dramatically under different contexts to push the biologic equilibrium toward the benefit of hosts vs. parasites. Therefore, these sRNA transfers may offer potential strategies to detect, prevent or treat parasite infections. Here, we review a brief history of the discovery of host erythrocyte sRNAs, their transfers and interactions in the context of P. falciparum infection. We also provide examples and discuss the functional significance of the reciprocal transfer of parasite-encoded sRNAs into hosts. These understandings of sRNA exchanges are put in the context of their implications for parasite pathogenesis, host defenses and the evolution of host polymorphisms driven by host interactions with these parasites.

libmpdata++ 1.0: a library of parallel MPDATA solvers for systems of generalised transport equations

NASA Astrophysics Data System (ADS)

Jaruga, A.; Arabas, S.; Jarecka, D.; Pawlowska, H.; Smolarkiewicz, P. K.; Waruszewski, M.

2015-04-01

This paper accompanies the first release of libmpdata++, a C++ library implementing the multi-dimensional positive-definite advection transport algorithm (MPDATA) on regular structured grid. The library offers basic numerical solvers for systems of generalised transport equations. The solvers are forward-in-time, conservative and non-linearly stable. The libmpdata++ library covers the basic second-order-accurate formulation of MPDATA, its third-order variant, the infinite-gauge option for variable-sign fields and a flux-corrected transport extension to guarantee non-oscillatory solutions. The library is equipped with a non-symmetric variational elliptic solver for implicit evaluation of pressure gradient terms. All solvers offer parallelisation through domain decomposition using shared-memory parallelisation. The paper describes the library programming interface, and serves as a user guide. Supported options are illustrated with benchmarks discussed in the MPDATA literature. Benchmark descriptions include code snippets as well as quantitative representations of simulation results. Examples of applications include homogeneous transport in one, two and three dimensions in Cartesian and spherical domains; a shallow-water system compared with analytical solution (originally derived for a 2-D case); and a buoyant convection problem in an incompressible Boussinesq fluid with interfacial instability. All the examples are implemented out of the library tree. Regardless of the differences in the problem dimensionality, right-hand-side terms, boundary conditions and parallelisation approach, all the examples use the same unmodified library, which is a key goal of libmpdata++ design. The design, based on the principle of separation of concerns, prioritises the user and developer productivity. The libmpdata++ library is implemented in C++, making use of the Blitz++ multi-dimensional array containers, and is released as free/libre and open-source software.

libmpdata++ 0.1: a library of parallel MPDATA solvers for systems of generalised transport equations

NASA Astrophysics Data System (ADS)

Jaruga, A.; Arabas, S.; Jarecka, D.; Pawlowska, H.; Smolarkiewicz, P. K.; Waruszewski, M.

2014-11-01

This paper accompanies first release of libmpdata++, a C++ library implementing the Multidimensional Positive-Definite Advection Transport Algorithm (MPDATA). The library offers basic numerical solvers for systems of generalised transport equations. The solvers are forward-in-time, conservative and non-linearly stable. The libmpdata++ library covers the basic second-order-accurate formulation of MPDATA, its third-order variant, the infinite-gauge option for variable-sign fields and a flux-corrected transport extension to guarantee non-oscillatory solutions. The library is equipped with a non-symmetric variational elliptic solver for implicit evaluation of pressure gradient terms. All solvers offer parallelisation through domain decomposition using shared-memory parallelisation. The paper describes the library programming interface, and serves as a user guide. Supported options are illustrated with benchmarks discussed in the MPDATA literature. Benchmark descriptions include code snippets as well as quantitative representations of simulation results. Examples of applications include: homogeneous transport in one, two and three dimensions in Cartesian and spherical domains; shallow-water system compared with analytical solution (originally derived for a 2-D case); and a buoyant convection problem in an incompressible Boussinesq fluid with interfacial instability. All the examples are implemented out of the library tree. Regardless of the differences in the problem dimensionality, right-hand-side terms, boundary conditions and parallelisation approach, all the examples use the same unmodified library, which is a key goal of libmpdata++ design. The design, based on the principle of separation of concerns, prioritises the user and developer productivity. The libmpdata++ library is implemented in C++, making use of the Blitz++ multi-dimensional array containers, and is released as free/libre and open-source software.

Dynamic modelling and simulation of linear Fresnel solar field model based on molten salt heat transfer fluid

NASA Astrophysics Data System (ADS)

Hakkarainen, Elina; Tähtinen, Matti

2016-05-01

Demonstrations of direct steam generation (DSG) in linear Fresnel collectors (LFC) have given promising results related to higher steam parameters compared to the current state-of-the-art parabolic trough collector (PTC) technology using oil as heat transfer fluid (HTF). However, DSG technology lacks feasible solution for long-term thermal energy storage (TES) system. This option is important for CSP technology in order to offer dispatchable power. Recently, molten salts have been proposed to be used as HTF and directly as storage medium in both line-focusing solar fields, offering storage capacity of several hours. This direct molten salt (DMS) storage concept has already gained operational experience in solar tower power plant, and it is under demonstration phase both in the case of LFC and PTC systems. Dynamic simulation programs offer a valuable effort for design and optimization of solar power plants. In this work, APROS dynamic simulation program is used to model a DMS linear Fresnel solar field with two-tank TES system, and example simulation results are presented in order to verify the functionality of the model and capability of APROS for CSP modelling and simulation.

Health insurance exchanges of past and present offer examples of features that could attract small-business customers.

PubMed

Gardiner, Terry

2012-02-01

The Affordable Care Act calls on states to create health insurance exchanges serving small businesses by 2014. These exchanges will allow small-business owners to pool their buying power, have more choices of health plans, and buy affordable health insurance. However, creating an exchange that appeals to small-business owners poses several challenges. Past and current exchanges provide valuable insights into the role exchanges can play, services they can offer, and design features that can make them successful. For example, states should allow insurance brokers to provide employers with advice and analysis regarding plans offered in the exchanges. Exchanges should also provide services to ease enrollment, such as a single application for all of the plans they offer, and make additional benefits, such as wellness programs, available on a stand-alone basis or within insurance plans.

Promoting geodiversity education with the help of earthcaching in Geoparks

NASA Astrophysics Data System (ADS)

Zecha, Stefanie

2016-04-01

The term 'geodiversity' was used as the geological equivalent of biodiversity for the first time in 1993. Education is especially relevant in the case of geodiversity and nature conservation because the greatest threat to geodiversity is ignorance (Gray 2004). Education for approving geodiversity sites can be supported by offering earth science themes in schools, in university or in national parks. The educators can use different methods, such as guided tours or normal wandering trails, in order to foster education in the field of geodiversity. In the last years the method of EarthCaching is coming up more and more, which offers the possibility of a virtual community, a physical place and the real world. Here, the question is how EarthCaching can foster geodiversity education in Geoparks. To answer this question, logged Earthcaches were also analyzed regarding to their educational content and if they function as a tool for tourism. At the end, best practice examples are presented.

Inhibition-Based Biomarkers for Autism Spectrum Disorder.

PubMed

Levin, April R; Nelson, Charles A

2015-07-01

Autism spectrum disorder (ASD) is a behaviorally defined and heterogeneous disorder. Biomarkers for ASD offer the opportunity to improve prediction, diagnosis, stratification by severity and subtype, monitoring over time and in response to interventions, and overall understanding of the underlying biology of this disorder. A variety of potential biomarkers, from the level of genes and proteins to network-level interactions, is currently being examined. Many of these biomarkers relate to inhibition, which is of particular interest because in many cases ASD is thought to be a disorder of imbalance between excitation and inhibition. Abnormalities in inhibition at the cellular level lead to emergent properties in networks of neurons. These properties take into account a more complete genetic and cellular background than findings at the level of individual genes or cells, and are able to be measured in live humans, offering additional potential as diagnostic biomarkers and predictors of behaviors. In this review we provide examples of how altered inhibition may inform the search for ASD biomarkers at multiple levels, from genes to cells to networks.

Daylighting in the workplace: Two new buildings offer a guiding light

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jackaway, A.; Littler, J.

1996-10-01

As environmental pressures intensify and energy efficiency remains paramount, there has been renewed interest in daylighting the workplace. Interestingly, daylighting`s resurgence is being furthered by mounting evidence of occupant dissatisfaction with predominantly electrically-lit offices, and two recent reports support growing concern that the lack of daylighting in these interiors has led not only to unhappy workers, but to potentially significant reductions in workplace productivity. Clearly pressure is mounting on designers to produce buildings responding to these concerns, and as the role of precedents in the evolution of design practice is unquestioned, demand has been increasing for publication of office-based daylightingmore » case studies. In an attempt to address this need, this paper examines two recently completed British buildings in which daylight has explicitly informed the architecture, and although data concerning the resulting energy savings is not yet available, these projects currently offer the design community two excellent examples of workplace daylighting where compelling visual environments are generating noteworthy occupant satisfaction.« less

[Anatomia sacra. Religiously motivated interventions on human or animal bodies].

PubMed

Gladigow, B

1995-01-01

Controlled surgery in the interior of human or animal bodies in classical antiquity was allowed only under certain circumstances. Bloody animal sacrifice and its rules for the interpretation of entrails as well as the rare examples of 'ritual anatomy' presented a religious framework for the opening of bodies. Greek mythology provided several examples of medical operations, for example, the Caesarean section, transplantations and plastic surgery. Great cultic significance was given to organ votives or reproductions of human inner organs which were offered in temples ex voto or with request for their curing. The anatomical knowledge transported along with these offerings represents a separate tradition different from the state of anatomical knowledge found in medical literature of the period.

Balancing the Budget through Social Exploitation: Why Hard Times Are Even Harder for Some

PubMed Central

Tropman, John; Nicklett, Emily

2013-01-01

In all societies needs and wants regularly exceed resources. Thus societies are always in deficit; demand always exceeds supply and “balancing the budget” is a constant social problem. To make matters somewhat worse, research suggests that need- and want-fulfillment tends to further stimulate the cycle of wantseeking rather than satiating desire. Societies use various resource-allocation mechanisms, including price, to cope with gaps between wants and resources. Social exploitation is a second mechanism, securing labor from population segments that can be coerced or convinced to perform necessary work for free or at below-market compensation. Using practical examples, this article develops a theoretical framework for understanding social exploitation. It then offers case examples of how different segments of the population emerge as exploited groups in the United States, due to changes in social policies. These exploitative processes have been exacerbated and accelerated by the economic downturn that began in 2007. PMID:23936753

Human Error: A Concept Analysis

NASA Technical Reports Server (NTRS)

Hansen, Frederick D.

2007-01-01

Human error is the subject of research in almost every industry and profession of our times. This term is part of our daily language and intuitively understood by most people however, it would be premature to assume that everyone's understanding of human error s the same. For example, human error is used to describe the outcome or consequence of human action, the causal factor of an accident, deliberate violations,a nd the actual action taken by a human being. As a result, researchers rarely agree on the either a specific definition or how to prevent human error. The purpose of this article is to explore the specific concept of human error using Concept Analysis as described by Walker and Avant (1995). The concept of human error is examined as currently used in the literature of a variety of industries and professions. Defining attributes and examples of model, borderline, and contrary cases are described. The antecedents and consequences of human error are also discussed and a definition of human error is offered.

Sports science needs more interdisciplinary, constraints-led research programmes: The case of water safety in New Zealand.

PubMed

Button, C; Croft, J L

2017-12-01

In the lead article of this special issue, Paul Glazier proposes that Newell's constraints model has the potential to contribute to a grand unified theory of sports performance in that it can help to integrate the disciplinary silos that have typically operated in isolation in sports and exercise science. With a few caveats discussed in this commentary, we agree with Glazier's proposal. However, his ideas suggest that there is a need to demonstrate explicitly how such an integration might occur within applied scientific research. To help fill this perceived 'gap' and thereby illustrate the value of adopting a constraints-led approach, we offer an example of our own interdisciplinary research programme. We believe our research on water safety is ideally suited to this task due to the diverse range of interacting constraints present and as such provides a tangible example of how this approach can unify different disciplinary perspectives examining an important aspect of sport performance. Copyright © 2017 Elsevier B.V. All rights reserved.

Argumentation in Legal Reasoning

NASA Astrophysics Data System (ADS)

Bench-Capon, Trevor; Prakken, Henry; Sartor, Giovanni

A popular view of what Artificial Intelligence can do for lawyers is that it can do no more than deduce the consequences from a precisely stated set of facts and legal rules. This immediately makes many lawyers sceptical about the usefulness of such systems: this mechanical approach seems to leave out most of what is important in legal reasoning. A case does not appear as a set of facts, but rather as a story told by a client. For example, a man may come to his lawyer saying that he had developed an innovative product while working for Company A. Now Company B has made him an offer of a job, to develop a similar product for them. Can he do this? The lawyer firstly must interpret this story, in the context, so that it can be made to fit the framework of applicable law. Several interpretations may be possible. In our example it could be seen as being governed by his contract of employment, or as an issue in Trade Secrets law.

Ambulatory Assessment.

PubMed

Carpenter, Ryan W; Wycoff, Andrea M; Trull, Timothy J

2016-08-01

In recent years, significant technological advances have changed our understanding of dynamic processes in clinical psychology. A particularly important agent of change has been ambulatory assessment (AA). AA is the assessment of individuals in their daily lives, combining the twin benefits of increased ecological validity and minimized retrospective biases. These benefits make AA particularly well-suited to the assessment of dynamic processes, and recent advancements in technology are providing exciting new opportunities to understand these processes in new ways. In the current article, we briefly detail the capabilities currently offered by smartphones and mobile physiological devices, as well as some of the practical and ethical challenges of incorporating these new technologies into AA research. We then provide several examples of recent innovative applications of AA methodology in clinical research, assessment, and intervention and provide a case example of AA data generated from a study utilizing multiple mobile devices. In this way, we aim to provide a sense of direction for researchers planning AA studies of their own.

The Case for Laboratory Developed Procedures

PubMed Central

Sabatini, Linda M.; Tsongalis, Gregory J.; Caliendo, Angela M.; Olsen, Randall J.; Ashwood, Edward R.; Bale, Sherri; Benirschke, Robert; Carlow, Dean; Funke, Birgit H.; Grody, Wayne W.; Hayden, Randall T.; Hegde, Madhuri; Lyon, Elaine; Pessin, Melissa; Press, Richard D.; Thomson, Richard B.

2017-01-01

An explosion of knowledge and technology is revolutionizing medicine and patient care. Novel testing must be brought to the clinic with safety and accuracy, but also in a timely and cost-effective manner, so that patients can benefit and laboratories can offer testing consistent with current guidelines. Under the oversight provided by the Clinical Laboratory Improvement Amendments, laboratories have been able to develop and optimize laboratory procedures for use in-house. Quality improvement programs, interlaboratory comparisons, and the ability of laboratories to adjust assays as needed to improve results, utilize new sample types, or incorporate new mutations, information, or technologies are positive aspects of Clinical Laboratory Improvement Amendments oversight of laboratory-developed procedures. Laboratories have a long history of successful service to patients operating under Clinical Laboratory Improvement Amendments. A series of detailed clinical examples illustrating the quality and positive impact of laboratory-developed procedures on patient care is provided. These examples also demonstrate how Clinical Laboratory Improvement Amendments oversight ensures accurate, reliable, and reproducible testing in clinical laboratories. PMID:28815200

Real World of Industrial Chemistry: The SHOP Process: An Example of Industrial Creativity.

ERIC Educational Resources Information Center

Reuben, Bryan; Wittcoff, Harold

1988-01-01

Discusses the Shell Higher Olefins Process (SHOP) in the manufacture of primary C11-C15 fatty alcohols. Offers examples and explanations of the four-step process. Gives uses for reaction products. (ML)

Foresight Study on the Risk Governance of New Technologies: The Case of Nanotechnology.

PubMed

Read, Sheona A K; Kass, Gary S; Sutcliffe, Hilary R; Hankin, Steven M

2016-05-01

Technology-led innovation represents an important driver of European economic and industrial competitiveness and offers solutions to societal challenges. In order to facilitate responsible innovation and public acceptance, a need exists to identify and implement oversight approaches focused on the effective risk governance of emerging technologies. This article describes a foresight study on the governance of new technologies, using nanotechnology as a case example. Following a mapping of the governance landscape, four plausible foresight scenarios were developed, capturing critical uncertainties for nanotechnology governance. Key governance elements were then stress tested within these scenarios to see how well they might perform in a range of possible futures and to inform identification of the strengths, weaknesses, opportunities, and threats for nanotechnology governance in Europe. Based on the study outcomes, recommendations are proposed regarding the development of governance associated with the responsible development of new technologies. © 2015 Society for Risk Analysis.

From OLS to VIIRS, an overview of nighttime satellite aerosol retrievals using artificial light sources

NASA Astrophysics Data System (ADS)

Zhang, J.; Miller, S. D.; Reid, J. S.; Hyer, E. J.; McHardy, T. M.

2015-12-01

Compared to abundant daytime satellite-based observations of atmospheric aerosol, observations at night are relatively scarce. In particular, conventional satellite passive imaging radiometers, which offer expansive swaths of spatial coverage compared to non-scanning lidar systems, lack sensitivity to most aerosol types via the available thermal infrared bands available at night. In this talk, we make the fundamental case for the importance of nighttime aerosol information in forecast models, and the need to mitigate the existing nocturnal gap. We review early attempts at estimating nighttime aerosol optical properties using the modulation of stable artificial surface lights. Initial algorithm development using DMSP Operational Linescan System (OLS) has graduated to refined techniques based on the Suomi-NPP Visible Infrared Imaging Radiometer Suite (VIIRS) Day/Night Band (DNB). We present examples of these retrievals for selected cases and compare the results to available surface-based point-source validation data.

A review of improved ethical practices in environmental and public health research: case examples from native communities.

PubMed

Quigley, Dianne

2006-04-01

This article presents a review of 14 case studies and articles of research ethics issues in the conduct of environmental and public health research with Native American and other indigenous populations. The purpose of this review is to highlight new practices in the ethical conduct of research with native community populations. The findings from this review can promote more dialogue and policy development on the issue of community protections in research. Formal guidelines exist in ethical codes for individual rights as human subjects, but there is a lack of development on community rights in the ethics of research. This review illustrates how community-based participatory research practices can provide working guidelines that can overcome past research harms. More important, the compilations of guidelines offer tested field methods for improving the ethical conduct of research with native community populations.

Harnessing Implementation Science to Increase the Impact of Health Equity Research.

PubMed

Chinman, Matthew; Woodward, Eva N; Curran, Geoffrey M; Hausmann, Leslie R M

2017-09-01

Health disparities are differences in health or health care between groups based on social, economic, and/or environmental disadvantage. Disparity research often follows 3 steps: detecting (phase 1), understanding (phase 2), and reducing (phase 3), disparities. Although disparities have narrowed over time, many remain. We argue that implementation science could enhance disparities research by broadening the scope of phase 2 studies and offering rigorous methods to test disparity-reducing implementation strategies in phase 3 studies. We briefly review the focus of phase 2 and phase 3 disparities research. We then provide a decision tree and case examples to illustrate how implementation science frameworks and research designs could further enhance disparity research. Most health disparities research emphasizes patient and provider factors as predominant mechanisms underlying disparities. Applying implementation science frameworks like the Consolidated Framework for Implementation Research could help disparities research widen its scope in phase 2 studies and, in turn, develop broader disparities-reducing implementation strategies in phase 3 studies. Many phase 3 studies of disparity-reducing implementation strategies are similar to case studies, whose designs are not able to fully test causality. Implementation science research designs offer rigorous methods that could accelerate the pace at which equity is achieved in real-world practice. Disparities can be considered a "special case" of implementation challenges-when evidence-based clinical interventions are delivered to, and received by, vulnerable populations at lower rates. Bringing together health disparities research and implementation science could advance equity more than either could achieve on their own.

Scenarios for Motivating the Learning of Variability: An Example in Finances

ERIC Educational Resources Information Center

Cordani, Lisbeth K.

2013-01-01

This article explores an example in finances in order to motivate the random variable learning to the very beginners in statistics. In addition, it offers a relationship between standard deviation and range in a very specific situation.

Lightning research: A user's lament

NASA Technical Reports Server (NTRS)

Golub, C. N.

1984-01-01

As a user of devices and procedures for lightning protection, the author is asking the lightning research community for cookbook recipes to help him solve his problems. He is lamenting that realistic devices are scarce and that his mission does not allow him the time nor the wherewithal to bridge the gap between research and applications. A few case histories are presented. In return for their help he is offering researchers a key to lightning technology--the use of the Eastern Test Range and its extensive resources as a proving ground for their experiment in the lightning capital of the United States. A current example is given--a joint lightning characterization project to take place there. Typical resources are listed.

Random functions via Dyson Brownian Motion: progress and problems

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wang, Gaoyuan; Battefeld, Thorsten

2016-09-05

We develope a computationally efficient extension of the Dyson Brownian Motion (DBM) algorithm to generate random function in C{sup 2} locally. We further explain that random functions generated via DBM show an unstable growth as the traversed distance increases. This feature restricts the use of such functions considerably if they are to be used to model globally defined ones. The latter is the case if one uses random functions to model landscapes in string theory. We provide a concrete example, based on a simple axionic potential often used in cosmology, to highlight this problem and also offer an ad hocmore » modification of DBM that suppresses this growth to some degree.« less

A framework for providing telecommuting as a reasonable accommodation: some considerations on a comparative case study.

PubMed

Kaplan, Shelley; Weiss, Sally; Moon, Nathan W; Baker, Paul

2006-01-01

Telecommuting, whether full time, part time, or over short periods when the need arises, can be an important accommodation for employees with disabilities. Indeed, telecommuting may be the only form of accommodation that offers employees whose disabilities fluctuate a means to stay consistently and gainfully employed. This article describes one employer's experience in considering a request for telecommuting as a reasonable accommodation for a particular employee. Drawing on real-life examples, both positive and negative, this article provides a win/win framework for decision-making that can help employers evaluate the use of telecommuting as a possible accommodation and facilitates open and ongoing communication between employer and employee.

Space astrophysics with large structures - CASES and P/OF. [Controls, Astrophysics, and Structures Experiment in Space and Pinhole/Occulter Facility

NASA Technical Reports Server (NTRS)

Hudson, Hugh S.; Davis, J. M.

1990-01-01

Space instruments for remote sensing, of the types used for astrophysics and solar-terrestrial physics among many disciplines, will grow to larger physical sizes in the future. The zero-g space environment does not inherently restrict such growth, because relatively lightweight structures can be used. Active servo control of the structures can greatly increase their size for a given mass. The Pinhole/Occulter Facility, a candidate Space Station attached payload, offers an example: it will achieve 0.2 arc s resolution by use of a 50-m baseline for coded-aperture telescopes for hard X-ray and gamma-ray imagers.

An Interdisciplinary Practical for Multimedia Engineering Students

ERIC Educational Resources Information Center

Marcos-Jorquera, Diego; Pertegal-Felices, María Luisa; Jimeno-Morenilla, Antonio; Gilar-Corbí, Raquel

2017-01-01

Interdisciplinary projects in the industry typically require collaboration between professionals from various fields. However, this relationship is not generally addressed in the training offered by university programs, which often ignore this interdisciplinary approach. This paper offers an example of interdisciplinary interaction through joint…

Intercultural Business Communication, International Students, and Experiential Learning.

ERIC Educational Resources Information Center

Cheney, Rebecca S.

2001-01-01

Outlines the relevance of experiential learning to the teaching of intercultural business communication. Offers several examples of activities offering structured interactions between United States and international students, which help students apply principles of intercultural business communication to a given situation. Discusses several…

Commentary: Binding Early Offers versus Caps for Medical Malpractice Claims?

PubMed Central

O'Connell, Jeffrey

2007-01-01

Like damages caps, early offer reform promises reduction in the costs of medical liability cases. In contrast to damages caps, early offer reform offers advantages to both claimant and defendant. Under early offer, the defendant would have the option to offer an injured patient periodic payments for the patient's net economic losses as they accrue, but not payments for noneconomic losses (pain and suffering). If an early offer were made and accepted, that would settle the claim. This commentary1 explains how an early offer reform might work and summarizes data from a recent closed claim study of medical malpractice cases in Texas and Florida. The data show widespread opportunities for successful early offers and provide evidence that substantial per case savings would result. PMID:17517116

On the Cutting Edge: Movements and Institutional Examples of Technological Disruption

ERIC Educational Resources Information Center

Leon, Marjorie Roth; Price, Todd Alan

2016-01-01

This chapter describes technological disruptions in higher education that pose challenges and offer opportunities to college and university students, faculty, and administrators. It provides examples of innovative responses being explored by 2-year and 4-year higher education institutions.

BioXSD: the common data-exchange format for everyday bioinformatics web services.

PubMed

Kalas, Matús; Puntervoll, Pål; Joseph, Alexandre; Bartaseviciūte, Edita; Töpfer, Armin; Venkataraman, Prabakar; Pettifer, Steve; Bryne, Jan Christian; Ison, Jon; Blanchet, Christophe; Rapacki, Kristoffer; Jonassen, Inge

2010-09-15

The world-wide community of life scientists has access to a large number of public bioinformatics databases and tools, which are developed and deployed using diverse technologies and designs. More and more of the resources offer programmatic web-service interface. However, efficient use of the resources is hampered by the lack of widely used, standard data-exchange formats for the basic, everyday bioinformatics data types. BioXSD has been developed as a candidate for standard, canonical exchange format for basic bioinformatics data. BioXSD is represented by a dedicated XML Schema and defines syntax for biological sequences, sequence annotations, alignments and references to resources. We have adapted a set of web services to use BioXSD as the input and output format, and implemented a test-case workflow. This demonstrates that the approach is feasible and provides smooth interoperability. Semantics for BioXSD is provided by annotation with the EDAM ontology. We discuss in a separate section how BioXSD relates to other initiatives and approaches, including existing standards and the Semantic Web. The BioXSD 1.0 XML Schema is freely available at http://www.bioxsd.org/BioXSD-1.0.xsd under the Creative Commons BY-ND 3.0 license. The http://bioxsd.org web page offers documentation, examples of data in BioXSD format, example workflows with source codes in common programming languages, an updated list of compatible web services and tools and a repository of feature requests from the community.

Redirecting traditional professional values to support safety: changing organisational culture in health care.

PubMed

Carroll, J S; Quijada, M A

2004-12-01

Professionals in healthcare organisations who seek to enhance safety and quality in an increasingly demanding industry environment often identify culture as a barrier to change. The cultural focus on individual autonomy, for example, seems to conflict with desired norms of teamwork, problem reporting, and learning. We offer a definition and explication of why culture is important to change efforts. A cultural analysis of health care suggests professional values that can be redirected to support change. We offer examples of organisations that drew upon cultural strengths to create new ways of working and gradually shifted the culture.

Redirecting traditional professional values to support safety: changing organisational culture in health care

PubMed Central

Carroll, J; Quijada, M

2004-01-01

Professionals in healthcare organisations who seek to enhance safety and quality in an increasingly demanding industry environment often identify culture as a barrier to change. The cultural focus on individual autonomy, for example, seems to conflict with desired norms of teamwork, problem reporting, and learning. We offer a definition and explication of why culture is important to change efforts. A cultural analysis of health care suggests professional values that can be redirected to support change. We offer examples of organisations that drew upon cultural strengths to create new ways of working and gradually shifted the culture. PMID:15576686

Examples of Sports-Based Youth Development Programs

ERIC Educational Resources Information Center

Berlin, Richard A.; Dworkin, Aaron; Eames, Ned; Menconi, Arn; Perkins, Daniel F.

2007-01-01

The authors provide examples of sports-based youth development programs and offer information about program mission and vision, program design and content, evaluation results, and program sustainability. The four sports-based youth development programs presented are Harlem RBI, Tenacity, Snowsports Outreach Society, and Hoops & Leaders…

Teaching Burke Using Advertisements.

ERIC Educational Resources Information Center

Larson, Charles U.

Kenneth Burke's concepts of identification, the five terms of dramatism, and strategic uses of ambiguity can be successfully taught to undergraduates if appropriate and familiar examples are used. Print and electronic advertising offer the instructor an up-to-date, familiar, and abundant source of classroom examples. Market segmentation models…

Maximizing Effectiveness Trials in PTSD and SUD Through Secondary Analysis: Benefits and Limitations Using the National Institute on Drug Abuse Clinical Trials Network "Women and Trauma" Study as a Case Example.

PubMed

Hien, Denise A; Campbell, Aimee N C; Ruglass, Lesia M; Saavedra, Lissette; Mathews, Abigail G; Kiriakos, Grace; Morgan-Lopez, Antonio

2015-09-01

Recent federal legislation and a renewed focus on integrative care models underscore the need for economical, effective, and science-based behavioral health care treatment. As such, maximizing the impact and reach of treatment research is of great concern. Behavioral health issues, including the frequent co-occurrence of substance use disorders (SUD) and posttraumatic stress disorder (PTSD), are often complex, with a myriad of factors contributing to the success of interventions. Although treatment guides for comorbid SUD/PTSD exist, most patients continue to suffer symptoms following the prescribed treatment course. Further, the study of efficacious treatments has been hampered by methodological challenges (e.g., overreliance on "superiority" designs (i.e., designs structured to test whether or not one treatment statistically surpasses another in terms of effect sizes) and short term interventions). Secondary analyses of randomized controlled clinical trials offer potential benefits to enhance understanding of findings and increase the personalization of treatment. This paper offers a description of the limits of randomized controlled trials as related to SUD/PTSD populations, highlights the benefits and potential pitfalls of secondary analytic techniques, and uses a case example of one of the largest effectiveness trials of behavioral treatment for co-occurring SUD/PTSD conducted within the National Drug Abuse Treatment Clinical Trials Network (NIDA CTN) and producing 19 publications. The paper concludes with implications of this secondary analytic approach to improve addiction researchers' ability to identify best practices for community-based treatment of these disorders. Innovative methods are needed to maximize the benefits of clinical studies and better support SUD/PTSD treatment options for both specialty and non-specialty healthcare settings. Moving forward, planning for and description of secondary analyses in randomized trials should be given equal consideration and care to the primary outcome analysis. Copyright © 2015 Elsevier Inc. All rights reserved.

What do external consultants from private and not-for-profit companies offer healthcare commissioners? A qualitative study of knowledge exchange

PubMed Central

Wye, Lesley; Brangan, Emer; Cameron, Ailsa; Gabbay, John; Klein, Jonathan H; Anthwal, Rachel; Pope, Catherine

2015-01-01

Objectives The use of external consultants from private and not-for-profit providers in the National Health Service (NHS) is intended to improve the quality of commissioning. The aim of this study was to learn about the support offered to healthcare commissioners, how external consultants and their clients work together and the perceived impact on the quality of commissioning. Setting NHS commissioning organisations and private and not-for-profit providers. Design Mixed methods case study of eight cases. Data collection 92 interviews with external consultants (n=36), their clients (n=47) and others (n=9). Observation of 25 training events and meetings. Documentation, for example, meeting minutes and reports. Analysis Constant comparison. Data were coded, summarised and analysed by the research team with a coding framework to facilitate cross-case comparison. Results In the four contracts presented here, external providers offered technical solutions (eg, software tools), outsourcing and expertise including project management, data interpretation and brokering relationships with experts. In assessing perceived impact on quality of commissioning, two contracts had limited value, one had short-term benefits and one provided short and longer term benefits. Contracts with commissioners actively learning, embedding and applying new skills were more valued. Other elements of success were: (1) addressing clearly agreed problems of relevance to managerial and operational staff (2) solutions co-produced at all organisational levels (3) external consultants working directly with clients to interpret data outputs to inform locally contextualised commissioning strategies. Without explicit knowledge exchange strategies, outsourcing commissioning to external providers resulted in the NHS clients becoming dependent. Conclusions NHS commissioning will be disadvantaged if commissioners both fail to learn in the short term from the knowledge of external providers and in the longer term lose local skills. Knowledge exchange mechanisms are a vital component of commissioning and should be embedded in external provider contracts. PMID:25716174

Overcoming barriers in care for the dying: Theoretical analysis of an innovative program model.

PubMed

Wallace, Cara L

2016-08-01

This article explores barriers to end-of-life (EOL) care (including development of a death denying culture, ongoing perceptions about EOL care, poor communication, delayed access, and benefit restrictions) through the theoretical lens of symbolic interactionism (SI), and applies general systems theory (GST) to a promising practice model appropriate for addressing these barriers. The Compassionate Care program is a practice model designed to bridge gaps in care for the dying and is one example of a program offering concurrent care, a recent focus of evaluation though the Affordable Care Act. Concurrent care involves offering curative care alongside palliative or hospice care. Additionally, the program offers comprehensive case management and online resources to enrollees in a national health plan (Spettell et al., 2009).SI and GST are compatible and interrelated theories that provide a relevant picture of barriers to end-of-life care and a practice model that might evoke change among multiple levels of systems. These theories promote insight into current challenges in EOL care, as well as point to areas of needed research and interventions to address them. The article concludes with implications for policy and practice, and discusses the important role of social work in impacting change within EOL care.

Periodic Vesicle Formation in Tectonic Fault Zones--an Ideal Scenario for Molecular Evolution.

PubMed

Mayer, Christian; Schreiber, Ulrich; Dávila, María J

2015-06-01

Tectonic fault systems in the continental crust offer huge networks of interconnected channels and cavities. Filled mainly with water and carbon dioxide (CO2), containing a wide variety of hydrothermal chemistry and numerous catalytic surfaces, they may offer ideal reaction conditions for prebiotic chemistry. In these systems, an accumulation zone for organic compounds will develop at a depth of approximately 1 km where CO2 turns sub-critical and dissolved components precipitate. At this point, periodic pressure changes caused for example by tidal influences or geyser activity may generate a cyclic process involving repeated phase transitions of carbon dioxide. In the presence of amphiphilic compounds, this will necessarily lead to the transient formation of coated water droplets in the gas phase and corresponding vesicular structures in the aqueous environment. During this process, the concentration of organic components inside the droplets and vesicles would be drastically increased, allowing for favorable reaction conditions and, in case of the vesicles generated, large trans-membrane concentration gradients. Altogether, the process of periodic formation and destruction of vesicles could offer a perfect environment for molecular evolution in small compartments and for the generation of protocells. The basic process of vesicle formation is reproduced experimentally with a lipid in a water/CO2 system.

Automated Simultaneous Assembly for Multistage Testing

ERIC Educational Resources Information Center

Breithaupt, Krista; Ariel, Adelaide; Veldkamp, Bernard P.

2005-01-01

This article offers some solutions used in the assembly of the computerized Uniform Certified Public Accountancy (CPA) licensing examination as practical alternatives for operational programs producing large numbers of forms. The Uniform CPA examination was offered as an adaptive multistage test (MST) beginning in April of 2004. Examples of…

Interfaith Leaders as Social Entrepreneurs

ERIC Educational Resources Information Center

Patel, Eboo; Meyer, Cassie

2012-01-01

Social entrepreneurs work to find concrete solutions to large-scale problems that are scalable and sustainable. In this article, the authors explore what the framework of social entrepreneurship might offer those seeking to positively engage religious diversity on college campuses, and highlight two programs that offer examples of what such…

Creating Poetry.

ERIC Educational Resources Information Center

Drury, John

Encouraging exploration and practice, this book offers hundreds of exercises and numerous tips covering every step involved in creating poetry. Each chapter is a self-contained unit offering an overview of material in the chapter, a definition of terms, and poetry examples from well-known authors designed to supplement the numerous exercises.…

Digital Storytelling: Expanding Media Possibilities for Learning

ERIC Educational Resources Information Center

McLellan, Hilary, Ed.

2008-01-01

Stories offer a powerful framework for engagement, reflection, and other important skills that young people need to learn. As digital media have expanded, so have the possibilities for creating stories. Here, several examples of those new possibilities are examined, examples that highlight student-produced online broadcasting initiatives,…

Newspapers in Adult Education. A Sourcebook.

ERIC Educational Resources Information Center

United Nations Educational, Scientific, and Cultural Organization, Paris (France).

This sourcebook offers 10 examples of how partnerships between educators and newspapers can play an active role in preparing informed citizens and in making adult education more attractive and effective. The examples are drawn from newspaper-education partnerships in the following countries: Argentina, Cameroon, Mali, Mexico, the Netherlands,…

Disintegration, Recognition, and Violence: A Theoretical Perspective

ERIC Educational Resources Information Center

Heitmeyer, Wilhelm; Anhut, Reimund

2008-01-01

The literature explaining deviance, criminality, or violence offers a broad spectrum of approaches in criminology and sociology. Mostly the theories focus on specific levels of explanation like the macrolevel (for example, strain theories) or the microlevel (for example, self-control theory). This article presents a relatively new theoretical…

The Importance of Studying Past Extreme Floods to Prepare for Uncertain Future Extremes

NASA Astrophysics Data System (ADS)

Burges, S. J.

2016-12-01

Hoyt and Langbein, 1955 in their book `Floods' wrote: " ..meteorologic and hydrologic conditions will combine to produce superfloods of unprecedented magnitude. We have every reason to believe that in most rivers past floods may not be an accurate measure of ultimate flood potentialities. It is this superflood with which we are always most concerned". I provide several examples to offer some historical perspective on assessing extreme floods. In one example, flooding in the Miami Valley, OH in 1913 claimed 350 lives. The engineering and socio-economic challenges facing the Morgan Engineering Co in how to mitigate against future flood damage and loss of life when limited information was available provide guidance about ways to face an uncertain hydroclimate future, particularly one of a changed climate. A second example forces us to examine mixed flood populations and illustrates the huge uncertainty in assigning flood magnitude and exceedance probability to extreme floods in such cases. There is large uncertainty in flood frequency estimates; knowledge of the total flood hydrograph, not the peak flood flow rate alone, is what is needed for hazard mitigation assessment or design. Some challenges in estimating the complete flood hydrograph in an uncertain future climate, including demands on hydrologic models and their inputs, are addressed.

Performance Scripts Creation: Processes and Applications

ERIC Educational Resources Information Center

Lyons, Paul

2006-01-01

Purpose: Seeks to explain some of the dynamics of scripts creation as used in training, to offer some theoretical underpinning regarding the influence of script creation on behavior and performance, and to offer some examples of how script creation is applied in training activities. Design/methodology/approach: The paper explains in detail and…

Institutional Ethics and Values. The Fundamentals. Board Basics.

ERIC Educational Resources Information Center

Corts, Thomas E.

1998-01-01

This booklet offers trustees of institutions of higher education a guide to the ethical principles upon which the institution should base its decisions. An introductory section offers actual examples of unethical decisions by single officials for which the institution was responsible. The following sections each explain a principle and offer…

Writing an Entertainment Review.

ERIC Educational Resources Information Center

Greenman, Robert; Aimone, Logan

2000-01-01

Discusses what a review should do, journalistic standards, and presenting a strong and consistent critique. Suggests other things to review besides movies, gives an example of success, and offers an exercise on writing a sidebar to accompany a movie review. Offers four reviews written by students, and a short essay about the occasional danger of…

Using Metacognition to Promote Learning. IDEA Paper #63

ERIC Educational Resources Information Center

Millis, Barbara J.

2016-01-01

Metacognition has increasingly been recognized as essential for learning. This paper defines metacognition, discusses its importance, and specifies how faculty can nurture it in students to promote positive learning outcomes. The paper then offers extensive examples based on two formats: (1) activities offered before, during, and after lessons or…

Actionable Postcolonial Theory in Education. Postcolonial Studies in Education

ERIC Educational Resources Information Center

Andreotti, Vanessa

2011-01-01

"Actionable Postcolonial Theory in Education" illustrates how postcolonial theory can be put to work in education. It offers an accessible and handy overview and comparison of postcolonial theory and other theoretical debates related to critiques of Western ethnocentrism and hegemony. It also offers examples that illustrate how a discursive strand…

77 FR 74283 - Clearing Requirement Determination Under Section 2(h) of the CEA

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-13

... where no DCO offers customer clearing.\\41\\ Freddie Mac requested clarification regarding the legal... represented by London Interbank Offered Rate (LIBOR), and three-month Treasury Bills. LIBOR contains credit... preparing for the move to mandatory clearing. For example, the Japanese Financial Services Authority (JFSA...

Lessons from "The Little Prince": Therapeutic Relationships with Children.

ERIC Educational Resources Information Center

Cowles, Janelle

1997-01-01

Explores the power of metaphor in therapy and offers as a relationship metaphor an example drawn from Saint-Exupery's classic children's tale. Discusses rituals and the necessity of counselors developing and nourishing relationships with their child clients. Claims that "The Little Prince" offers a way of being with children. (RJM)

Making DATA Work: A Process for Conducting Action Research

ERIC Educational Resources Information Center

Young, Anita; Kaffenberger, Carol

2013-01-01

This conceptual model introduces a process to help school counselors use data to drive decision making and offers examples to implement the process. A step-by-step process is offered to help school counselors and school counselor supervisors address educational issues, close achievement gaps, and demonstrate program effectiveness. To illustrate…

RUGs and "Medi-Cal" systems for classifying nursing home patients.

PubMed

Grimaldi, P L

1985-12-01

Medicare and most state Medicaid programs currently use indirect case-mix measures to determine reimbursement for nursing home care. In the future, however, they probably will incorporate more direct case-mix measures into their payment systems. Care must be exercised in designing a case-based prospective payment system to ensure that its financial incentives motivate providers to expedite recovery, prevent deterioration, and admit heavy-care patients. For example, although use of a services-rendered approach helps guarantee that care will be provided when needed, it also offers providers an incentive to furnish a service regardless of whether it is in the patient's best interest. Consideration must be given to the frequency with which patients are reassessed. The implications of the timing of reassessments for quality of care also must be studied. Ideally, quality would be measured on an outcome basis--that is, payment would depend on whether targeted goals for individual patients are reached--rather than on structural or process measures alone. Two recent classification systems--Resource Utilization Groups and Medi-Cal groups--may serve as models for case-based prospective payment systems. Each method classifies patients into distinct, meaningful categories based on activities of daily living and services received.

Noticing the Way: Translingual Possibility and Basic Writers

ERIC Educational Resources Information Center

Stanley, Sarah

2013-01-01

This article presents a pedagogical practice for noticing and negotiating error in a multilingual classroom. Two examples from a classroom are compared to demonstrate the importance of "noticing" in the context of translingual pedagogy. The author's first example offers an attempt to negotiate an error with a multilingual writer without…

75 FR 36395 - Guidance on Sound Incentive Compensation Policies

Federal Register 2010, 2011, 2012, 2013, 2014

2010-06-25

... response to comments. For example, the final guidance includes several provisions designed to reduce burden..., FDIC and OTS (collectively, the Agencies) are adopting final guidance designed to help ensure that... risks that are not consistent with the long-term health of the organization. For example, offering large...

76 FR 16570 - Interest Rate Risk

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-24

... greater than 10 years in the statement of financial condition of its most recent call report. For example..., asset valuation, or net economic value); Choose tests, such as interest rate shocks, that the credit... activities. For example, a credit union that offers basic share accounts, only short-term loans, i.e., no...

Using Multimedia To Develop Musicianship.

ERIC Educational Resources Information Center

Fenton, Kevin

1998-01-01

Proposes that high school choir teachers utilize multimedia technology in order to provide students with simultaneous aural and visual examples of various musical concepts. Offers examples using a multimedia approach to teach John Bennet's "Weep, O Mine Eyes" and Randall Thompson's "The Road Not Taken." Includes a list for selected software. (CMK)

Adapting the Individual Placement and Support Model with Homeless Young Adults

ERIC Educational Resources Information Center

Ferguson, Kristin M.; Xie, Bin; Glynn, Shirley

2012-01-01

Background: Prior research reveals high unemployment rates among homeless young adults. The literature offers many examples of using evidence-based supported employment models with vulnerable populations to assist them in obtaining and maintaining competitive employment; yet few examples exist to date with homeless young adults with mental…

Learning Styles of African American Children: Instructional Implications

ERIC Educational Resources Information Center

Hale, Janice Ellen

2016-01-01

This article offers examples of valiant efforts to develop meaningful instructional implications from learning styles scholarship. Additionally, an example is given of an advance in the public policy arena that merges the efforts of psychological scholars with that of lawmakers to apply their research to effect change for children. The…

Evaluation Practice and Theory: Up and down the Ladder of Abstraction

ERIC Educational Resources Information Center

Leviton, Laura C.

2015-01-01

Debra Rog presented the 2014 Eleanor Chelimsky Forum address, offering ways to integrate evaluation theory and practice by abundant use of practice examples. These examples illustrate the effective use of the Ladder of Abstraction from semantics, working from the concrete to the abstract and back again.

Video-Based Test Questions: A Novel Means of Evaluation

ERIC Educational Resources Information Center

Hertenstein, Matthew J.; Wayand, Joseph F.

2008-01-01

Many psychology instructors present videotaped examples of behavior at least occasionally during their courses. However, few include video clips during examinations. We provide examples of video-based questions, offer guidelines for their use, and discuss their benefits and drawbacks. In addition, we provide empirical evidence to support the use…

Chemistry. Focus on Excellence, Volume 3, Number 2.

ERIC Educational Resources Information Center

Penick, John E., Ed.; Krajcik, Joseph, Ed.

Eight examples of innovative and outstanding chemistry programs are described. These programs were selected using state criteria and at least four independent reviewers. While Project Synthesis offered a desired state, these examples of excellence provided views of what is already a reality. Included are the goals of an exemplary science program…

Bringing the Sociological into the Discussion: Teaching the Sociology of Genocide and the Holocaust.

ERIC Educational Resources Information Center

Abowitz, Deborah A.

2002-01-01

Illustrates how to use sociological concepts and theory in teaching about genocide and the Holocaust. Offers three examples to demonstrate how sociology can be integrated into the study of genocide and the Holocaust. Relates topics addressed in examples, such as gender issues. (CMK)

The Role of New Media in the Knowledge Explosion.

ERIC Educational Resources Information Center

Hawkridge, David

This paper examines two examples in Third World countries of new media being used for national development through education. The first example is the increase in television universities in China, i.e., universities that offer courses through broadcast educational television as well as videotaped recordings of television programs. Positive results…

Online Book Clubs: Bridges between Old and New Literacies Practices

ERIC Educational Resources Information Center

Scharber, Cassandra

2009-01-01

In this Digital Literacies column, online book clubs are offered as one example of how to effectively bridge old and new literacy practices. These Internet-based book clubs capitalize on children's interest in new literacy practices while complementing, and hopefully encouraging, traditional reading practices. Examples from online book clubs…

Revisiting Information Technology tools serving authorship and editorship: a case-guided tutorial to statistical analysis and plagiarism detection

PubMed Central

Bamidis, P D; Lithari, C; Konstantinidis, S T

2010-01-01

With the number of scientific papers published in journals, conference proceedings, and international literature ever increasing, authors and reviewers are not only facilitated with an abundance of information, but unfortunately continuously confronted with risks associated with the erroneous copy of another's material. In parallel, Information Communication Technology (ICT) tools provide to researchers novel and continuously more effective ways to analyze and present their work. Software tools regarding statistical analysis offer scientists the chance to validate their work and enhance the quality of published papers. Moreover, from the reviewers and the editor's perspective, it is now possible to ensure the (text-content) originality of a scientific article with automated software tools for plagiarism detection. In this paper, we provide a step-bystep demonstration of two categories of tools, namely, statistical analysis and plagiarism detection. The aim is not to come up with a specific tool recommendation, but rather to provide useful guidelines on the proper use and efficiency of either category of tools. In the context of this special issue, this paper offers a useful tutorial to specific problems concerned with scientific writing and review discourse. A specific neuroscience experimental case example is utilized to illustrate the young researcher's statistical analysis burden, while a test scenario is purpose-built using open access journal articles to exemplify the use and comparative outputs of seven plagiarism detection software pieces. PMID:21487489

Integration of Spatial and Social Network Analysis in Disease Transmission Studies.

PubMed

Emch, Michael; Root, Elisabeth D; Giebultowicz, Sophia; Ali, Mohammad; Perez-Heydrich, Carolina; Yunus, Mohammad

2012-01-01

This study presents a case study of how social network and spatial analytical methods can be used simultaneously for disease transmission modeling. The paper first reviews strategies employed in previous studies and then offers the example of transmission of two bacterial diarrheal diseases in rural Bangladesh. The goal is to understand how diseases vary socially above and beyond the effects of the local neighborhood context. Patterns of cholera and shigellosis incidence are analyzed in space and within kinship-based social networks in Matlab, Bangladesh. Data include a spatially referenced longitudinal demographic database which consists of approximately 200,000 people and laboratory-confirmed cholera and shigellosis cases from 1983 to 2003. Matrices are created of kinship ties between households using a complete network design and distance matrices are also created to model spatial relationships. Moran's I statistics are calculated to measure clustering within both social and spatial matrices. Combined spatial effects-spatial disturbance models are built to simultaneously analyze spatial and social effects while controlling for local environmental context. Results indicate that cholera and shigellosis always clusters in space and only sometimes within social networks. This suggests that the local environment is most important for understanding transmission of both diseases however kinship-based social networks also influence their transmission. Simultaneous spatial and social network analysis can help us better understand disease transmission and this study has offered several strategies on how.

Integration of Spatial and Social Network Analysis in Disease Transmission Studies

PubMed Central

Root, Elisabeth D; Giebultowicz, Sophia; Ali, Mohammad; Perez-Heydrich, Carolina; Yunus, Mohammad

2013-01-01

This study presents a case study of how social network and spatial analytical methods can be used simultaneously for disease transmission modeling. The paper first reviews strategies employed in previous studies and then offers the example of transmission of two bacterial diarrheal diseases in rural Bangladesh. The goal is to understand how diseases vary socially above and beyond the effects of the local neighborhood context. Patterns of cholera and shigellosis incidence are analyzed in space and within kinship-based social networks in Matlab, Bangladesh. Data include a spatially referenced longitudinal demographic database which consists of approximately 200,000 people and laboratory-confirmed cholera and shigellosis cases from 1983 to 2003. Matrices are created of kinship ties between households using a complete network design and distance matrices are also created to model spatial relationships. Moran's I statistics are calculated to measure clustering within both social and spatial matrices. Combined spatial effects-spatial disturbance models are built to simultaneously analyze spatial and social effects while controlling for local environmental context. Results indicate that cholera and shigellosis always clusters in space and only sometimes within social networks. This suggests that the local environment is most important for understanding transmission of both diseases however kinship-based social networks also influence their transmission. Simultaneous spatial and social network analysis can help us better understand disease transmission and this study has offered several strategies on how. PMID:24163443

Stressors associated with dyspnea in childhood: patients' insights and a case report.

PubMed

Anbar, Ran D

2004-10-01

To highlight the concept that stress can be associated with dyspnea in children. A chart review identified 22 patients (age range, 9-17 years) referred to a pediatric pulmonologist, who were offered instruction in self-hypnosis for treatment of dyspnea that persisted despite medical therapy. Patients were offered the opportunity to use hypnosis to gain insight into the causes of their dyspnea. The dyspnea resolved in 18 of the 22 patients within 1 month of instruction in self-hypnosis for relaxation and symptom reduction. Eight of the 22 patients (age range, 11-16 years) chose to use hypnosis for insight. Using automatic word processing, they explained that their dyspnea was associated with stressful situations, or that it reduced the chances of having to experience an uncomfortable situation. For example, a girl with dyspnea resulting from vocal cord dysfunction realized during hypnosis that she developed her symptom in order to prevent herself from talking about information that might cause discomfort were it disclosed. As soon as the patient decided that she could trust herself to handle the information appropriately, her symptom resolved. Dyspnea may provide patients with a way of expressing their reactions to perceived or anticipated stress. Thus, stress reduction interventions may prove very helpful in resolving this symptom. However, in some cases gaining an insight into the potential cause of the dyspnea may increase the effectiveness of therapy.

Revisiting Information Technology tools serving authorship and editorship: a case-guided tutorial to statistical analysis and plagiarism detection.

PubMed

Bamidis, P D; Lithari, C; Konstantinidis, S T

2010-12-01

With the number of scientific papers published in journals, conference proceedings, and international literature ever increasing, authors and reviewers are not only facilitated with an abundance of information, but unfortunately continuously confronted with risks associated with the erroneous copy of another's material. In parallel, Information Communication Technology (ICT) tools provide to researchers novel and continuously more effective ways to analyze and present their work. Software tools regarding statistical analysis offer scientists the chance to validate their work and enhance the quality of published papers. Moreover, from the reviewers and the editor's perspective, it is now possible to ensure the (text-content) originality of a scientific article with automated software tools for plagiarism detection. In this paper, we provide a step-bystep demonstration of two categories of tools, namely, statistical analysis and plagiarism detection. The aim is not to come up with a specific tool recommendation, but rather to provide useful guidelines on the proper use and efficiency of either category of tools. In the context of this special issue, this paper offers a useful tutorial to specific problems concerned with scientific writing and review discourse. A specific neuroscience experimental case example is utilized to illustrate the young researcher's statistical analysis burden, while a test scenario is purpose-built using open access journal articles to exemplify the use and comparative outputs of seven plagiarism detection software pieces.

Adjuncts in the IVF laboratory: where is the evidence for 'add-on' interventions?

PubMed

Harper, Joyce; Jackson, Emily; Sermon, Karen; Aitken, Robert John; Harbottle, Stephen; Mocanu, Edgar; Hardarson, Thorir; Mathur, Raj; Viville, Stephane; Vail, Andy; Lundin, Kersti

2017-03-01

Globally, IVF patients are routinely offered and charged for a selection of adjunct treatments and tests or 'add-ons' that they are told may improve their chance of a live birth, despite there being no clinical evidence supporting the efficacy of the add-on. Any new IVF technology claiming to improve live birth rates (LBR) should, in most cases, first be tested in an appropriate animal model, then in clinical trials, to ensure safety, and finally in a randomized controlled trial (RCT) to provide high-quality evidence that the procedure is safe and effective. Only then should the technique be considered as 'routine' and only when applied to the similar patient population as those studied in the RCT. Even then, further pediatric and long-term follow-up studies will need to be undertaken to examine the long-term safety of the procedure. Alarmingly, there are currently numerous examples where adjunct treatments are used in the absence of evidence-based medicine and often at an additional fee. In some cases, when RCTs have shown the technique to be ineffective, it is eventually withdrawn from the clinic. In this paper, we discuss some of the adjunct treatments currently being offered globally in IVF laboratories, including embryo glue and adherence compounds, sperm DNA fragmentation, time-lapse imaging, preimplantation genetic screening, mitochondria DNA load measurement and assisted hatching. We examine the evidence for their safety and efficacy in increasing LBRs. We conclude that robust studies are needed to confirm the safety and efficacy of any adjunct treatment or test before they are offered routinely to IVF patients. © The Author 2017. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

An industry update: what is the latest news in the therapeutic delivery field?

PubMed

Reis, Catarina Pinto

2018-05-01

The present industry update covers the period 1-31 December 2017. Information was sourced primarily from scientific literature and various news websites, company press releases, regulatory and patent agencies. The most representative (not all) examples of research are herein described and they are mainly focused on metabolic diseases, cancer, blood pressure diseases, eyes diseases and, in some cases, in rare diseases. In this paper, there was a clear positive approval tendency for several companies where they offered novel therapeutic delivery candidates. Some patents related to the therapeutic field were also published during this month. Finally, the US FDA announced the availability of a draft guidance for industry for products containing nanomaterials (investigational, pre-market and post-market submissions).

Cultural evolution: The case of babies’ first names

NASA Astrophysics Data System (ADS)

Xi, Ning; Zhang, Zi-Ke; Zhang, Yi-Cheng; Ge, Zehui; She, Li; Zhang, Kui

2014-07-01

In social sciences, there is currently rare consensus on the underlying mechanism for cultural evolution, partially due to lack of suitable data. The evolution of first names of newborn babies offers a remarkable example for such researches. In this paper, we employ the historical data on baby names from the United States to investigate the evolutionary process of culture, in particular focusing on how inequality among baby names changes over time. Then we propose a stochastic model where individual choice is determined by both individual preference and social influence, and show that the decrease in the strength of social influence can account for all the observed empirical features. Therefore, we claim that the weakening of social influence drives cultural evolution.

OntoGene web services for biomedical text mining.

PubMed

Rinaldi, Fabio; Clematide, Simon; Marques, Hernani; Ellendorff, Tilia; Romacker, Martin; Rodriguez-Esteban, Raul

2014-01-01

Text mining services are rapidly becoming a crucial component of various knowledge management pipelines, for example in the process of database curation, or for exploration and enrichment of biomedical data within the pharmaceutical industry. Traditional architectures, based on monolithic applications, do not offer sufficient flexibility for a wide range of use case scenarios, and therefore open architectures, as provided by web services, are attracting increased interest. We present an approach towards providing advanced text mining capabilities through web services, using a recently proposed standard for textual data interchange (BioC). The web services leverage a state-of-the-art platform for text mining (OntoGene) which has been tested in several community-organized evaluation challenges,with top ranked results in several of them.

Ethical Issues in mHealth Research Involving Persons Living with HIV/AIDS and Substance Abuse

PubMed Central

Labrique, Alain B.; Kirk, Gregory D.; Westergaard, Ryan P.; Merritt, Maria W.

2013-01-01

We aim to raise awareness and stimulate dialogue among investigators and research ethics committees regarding ethical issues that arise specifically in the design and conduct of mHealth research involving persons living with HIV/AIDS and substance abuse. Following a brief background discussion of mHealth research in general, we offer a case example to illustrate the characteristics of mHealth research involving people living with HIV/AIDS and substance abuse. With reference to a well-established systematic general ethical framework for biomedical research with human participants, we identify a range of ethical issues that have particular salience for the protection of participants in mHealth research on HIV/AIDS and substance abuse. PMID:24171110

An ecological process model of systems change.

PubMed

Peirson, Leslea J; Boydell, Katherine M; Ferguson, H Bruce; Ferris, Lorraine E

2011-06-01

In June 2007 the American Journal of Community Psychology published a special issue focused on theories, methods and interventions for systems change which included calls from the editors and authors for theoretical advancement in this field. We propose a conceptual model of systems change that integrates familiar and fundamental community psychology principles (succession, interdependence, cycling of resources, adaptation) and accentuates a process orientation. To situate our framework we offer a definition of systems change and a brief review of the ecological perspective and principles. The Ecological Process Model of Systems Change is depicted, described and applied to a case example of policy driven systems level change in publicly funded social programs. We conclude by identifying salient implications for thinking and action which flow from the Model.

Distributing responsibility in the debate on sustainable biofuels.

PubMed

Landeweerd, Laurens; Osseweijer, Patricia; Kinderlerer, Julian

2009-12-01

In the perception of technology innovation two world views compete for domination: technological and social determinism. Technological determinism holds that societal change is caused by technological developments, social determinism holds the opposite. Although both were quite central to discussion in the philosophy, history and sociology of technology in the 1970s and 1980s, neither is seen as mainstream now. They do still play an important role as background philosophies in societal debates and offer two very different perspectives on where the responsibilities for an ethically sound development of novel technologies lie. In this paper we will elaborate on these to two opposing views on technology development taking the recent debate on the implementation of biofuels as a case example.

Plant parasite control and soil fauna diversity.

PubMed

Lavelle, Patrick; Blouin, Manuel; Boyer, Johnny; Cadet, Patrice; Laffray, Daniel; Pham-Thi, Anh-Thu; Reversat, Georges; Settle, William; Zuily, Yasmine

2004-07-01

The use of pesticides to control plant parasites and diseases has generated serious problems of public health and environmental quality, leading to the promotion of alternative Integrated Pest Management strategies that tend to rely more on natural processes and the active participation of farmers as observers and experimenters in their own fields. We present three case studies that point at different options provided by locally available populations of soil organisms, the maintenance of diverse populations of pests or increased resistance of plants to pest attacks by their interactions with earthworms and other useful soil organisms. These examples demonstrate the diversity of options offered by the non-planned agro-ecosystem diversity in pest control and the need to identify management options that maintain this biodiversity.

EEOC says temporary workers qualify for ADA protection. Equal Employment Opportunity Commission.

PubMed

1998-01-23

The Equal Employment Opportunity Commission (EEOC) issued guidelines clarifying that both employers and staffing agencies can be held liable for discrimination and harassment of temporary or contingent workers. These workers are often viewed as independent contractors, and not employees. The guidance clarifies the employee-employer relationship, holding both the employment firm and the client accountable for discrimination and harassment and offering protection for this class of worker under the Americans with Disabilities Act (ADA) and other anti-discrimination statutes. The guidance also contains two case examples of how the ADA applies to contractual workers with HIV. The staffing firm and client each must count every worker with whom there is an employment relationship, and are prohibited from discriminating against each other's employees.

Resolving the sexual intimacy paradox: a developmental model for the treatment of sexual desire disorders.

PubMed

Lobitz, W C; Lobitz, G K

1996-01-01

Although relationship factors are an important component in the evaluation and treatment of hypoactive sexual desire (HSD) disorders, a sexual intimacy paradox often occurs wherein many couples increase the intimacy in their relationship while their sexual desire continues to decline. To resolve the apparent paradox and to further our understanding of the relationship between intimacy and eroticism, we offer a developmental model of sexual intimacy as a guide to treating the interpersonal aspects of HSD and other sexual dysfunctions. This model expands Erikson's developmental phase of intimacy into five elements: conflagration, merger, fusion, differentiation, and integration. The model is described and case examples are presented as illustrations of the therapeutic issues and resolutions within each element.

OntoGene web services for biomedical text mining

PubMed Central

2014-01-01

Text mining services are rapidly becoming a crucial component of various knowledge management pipelines, for example in the process of database curation, or for exploration and enrichment of biomedical data within the pharmaceutical industry. Traditional architectures, based on monolithic applications, do not offer sufficient flexibility for a wide range of use case scenarios, and therefore open architectures, as provided by web services, are attracting increased interest. We present an approach towards providing advanced text mining capabilities through web services, using a recently proposed standard for textual data interchange (BioC). The web services leverage a state-of-the-art platform for text mining (OntoGene) which has been tested in several community-organized evaluation challenges, with top ranked results in several of them. PMID:25472638

Online citizen science games: Opportunities for the biological sciences.

PubMed

Curtis, Vickie

2014-12-01

Recent developments in digital technologies and the rise of the Internet have created new opportunities for citizen science. One of these has been the development of online citizen science games where complex research problems have been re-imagined as online multiplayer computer games. Some of the most successful examples of these can be found within the biological sciences, for example, Foldit, Phylo and EteRNA. These games offer scientists the opportunity to crowdsource research problems, and to engage with those outside the research community. Games also enable those without a background in science to make a valid contribution to research, and may also offer opportunities for informal science learning.

Attachment-Focused Psychotherapy and the Wounded Self.

PubMed

Spiegel, Eric B

2016-07-01

The concept of the "wounded self" (Wolfe, 2005) offers an integrative theoretical framework for self-wounds and their developmental origins. Alladin (2013, 2014, 2016) integrated hypnotherapy into this model to comprehensively address the unconscious protective mechanisms and maladaptive conscious cognitive strategies of the wounded self. The purpose of this article is to propose how an attachment-focused psychotherapy could be utilized in working with the wounded self. With its emphasis on developmental maturation through the frame of the attachment relationship, attachment theory is well-positioned to offer conceptual and treatment insights in treating the wounded self. E. B. Spiegel's (2016) attunement, representation, and mentalization approach to attachment-focused psychotherapy described how hypnosis can be utilized across attachment processes of attunement, representation, and mentalization toward structural maturation and developmental repair of patients with histories of complex relational trauma. In this article, the attunement, representation, and mentalization attachment approach and associated interventions are further explicated in the treatment of self-wounds in the borderline and narcissistic spectrums of personality organization. These principles of conceptualization and treatment interventions are then applied in a case example.

Capillary glucose meter accuracy and sources of error in the ambulatory setting.

PubMed

Lunt, Helen; Florkowski, Christopher; Bignall, Michael; Budgen, Christopher

2010-03-05

Hand-held glucose meters are used throughout the health system by both patients with diabetes and also by health care practitioners. Glucose meter technology is constantly evolving. The current generation of meters and strips are quick to use and require a very small volume of blood. This review aims to describe meters currently available in New Zealand, for use in the ambulatory setting. It also aims to discuss the limits of meter performance and provide technical information that is relevant to the clinician, using locally available data. Commoner causes and consequences of end-user (patient and health professional) error are illustrated using clinical case examples. No meter offers definite advantages over other meters in all clinical situations, rather meters should be chosen because they fit the needs of individual patients and because the provider is able to offer appropriate educational and quality assurance backup to the meter user. A broad understanding of the advantages and disadvantages of the subsidised meter systems available in New Zealand will help the health practitioner decide when it is in the best interests of their patients to change or update meter technology.

The use of music therapy to address the suffering in advanced cancer pain.

PubMed

Magill, L

2001-01-01

Pain associated with advanced cancer is multifaceted and complex, and is influenced by physiological, psychological, social, and spiritual phenomena. Suffering may be identified in patients when pain is associated with impending loss, increased dependency, and an altered understanding of one's existential purpose. Comprehensive pain management aims to address problematic symptoms in order to improve comfort, peace of mind, and quality of life. Music therapy is a treatment modality of great diversity that can offer a range of benefits to patients with advanced cancer pain and symptoms of suffering. Music therapists perform comprehensive assessments that include reviews of social, cultural, and medical history; current medical status; and the ways in which emotions are affecting the pain. A variety of music therapy techniques may be used, including vocal techniques, listening, and instrumental techniques. These techniques provide opportunities for exploration of the feelings and issues compounding the pain experience. Case examples are presented to demonstrate the "lifting", "transporting", and "bringing of peace" qualities of music that offer patients moments of release, reflection, and renewal.

Advanced multispectral dynamic thermography as a new tool for inspection of gas-fired furnaces

NASA Astrophysics Data System (ADS)

Pregowski, Piotr; Goleniewski, Grzegorz; Komosa, Wojciech; Korytkowski, Waldemar

2004-04-01

The main special feature of elaborated method is that the dynamic IR thermography (DIRT) bases on forming of single image consisting of pixels of chosen minimum (IMAX) or maximum (IMAX) value, noted during adequately long sequence of thermograms with total independence to the moment of its (image's) capture. In this way, additive or suppressed interferences of fluctuating character become bypassed. Due to this method thereafter elaborated in classic way such "artificial thermogram" offers the quality impossible to achieve with a classic "one shot" method. Although preliminary, results obtained clearly show great potential of the method. and confirmed the validity in decreasing errors caused by fluctuating disturbances. In the case of process furnaces of gas-fired type and especially of coal-fired, application of presented solutions should result in significant increasing the reliability of IR thermography application. By use of properly chosen optical filters and algorithm, elaborated method offers a new potential attractive to test temperature problems other than in tubes , as for example symmetry and efficiency of the furnace heaters.

Toward a Conceptual Framework for Blending Social and Biophysical Attributes in Conservation Planning: A Case-Study of Privately-Conserved Lands

NASA Astrophysics Data System (ADS)

Pasquini, Lorena; Twyman, Chasca; Wainwright, John

2010-11-01

There has been increasing recognition within systematic conservation planning of the need to include social data alongside biophysical assessments. However, in the approaches to identify potential conservation sites, there remains much room for improvement in the treatment of social data. In particular, few rigorous methods to account for the diversity of less-easily quantifiable social attributes that influence the implementation success of conservation sites (such as willingness to conserve) have been developed. We use a case-study analysis of private conservation areas within the Little Karoo, South Africa, as a practical example of the importance of incorporating social data into the process of selecting potential conservation sites to improve their implementation likelihood. We draw on extensive data on the social attributes of our case study obtained from a combination of survey questionnaires and semi-structured interviews. We discuss the need to determine the social attributes that are important for achieving the chosen implementation strategy by offering four tested examples of important social attributes in the Little Karoo: the willingness of landowners to take part in a stewardship arrangement, their willingness to conserve, their capacity to conserve, and the social capital among private conservation area owners. We then discuss the process of using an implementation likelihood ratio (derived from a combined measure of the social attributes) to assist the choice of potential conservation sites. We conclude by summarizing our discussion into a simple conceptual framework for identifying biophysically-valuable sites which possess a high likelihood that the desired implementation strategy will be realized on them.

Patient-centered innovation in health care organizations: a conceptual framework and case study application.

PubMed

Hernandez, Susan E; Conrad, Douglas A; Marcus-Smith, Miriam S; Reed, Peter; Watts, Carolyn

2013-01-01

Patient-centered innovation is spreading at the federal and state levels. A conceptual framework can help frame real-world examples and extract systematic learning from an array of innovative applications currently underway. The statutory, economic, and political environment in Washington State offers a special contextual laboratory for observing the interplay of these factors. We propose a framework for understanding the process of initiating patient-centered innovations-particularly innovations addressing patient-centered goals of improved access, continuity, communication and coordination, cultural competency, and family- and person-focused care over time. The framework to a case study of a provider organization in Washington State actively engaged in such innovations was applied in this article. We conducted a selective review of peer-reviewed evidence and theory regarding determinants of organizational change. On the basis of the literature review and the particular examples of patient-centric innovation, we developed a conceptual framework. Semistructured key informant interviews were conducted to illustrate the framework with concrete examples of patient-centered innovation. The primary determinants of initiating patient-centered innovation are (a) effective leadership, with the necessary technical and professional expertise and creative skills; (b) strong internal and external motivation to change; (c) clear and internally consistent organizational mission; (d) aligned organizational strategy; (e) robust organizational capability; and (f) continuous feedback and organizational learning. The internal hierarchy of actors is important in shaping patient-centered innovation. External financial incentives and government regulations also significantly shape innovation. Patient-centered care innovation is a complex process. A general framework that could help managers and executives organize their thoughts around innovation within their organization is presented.

Patient autonomy and choice in healthcare: self-testing devices as a case in point.

PubMed

Greaney, Anna-Marie; O'Mathúna, Dónal P; Scott, P Anne

2012-11-01

This paper aims to critique the phenomenon of advanced patient autonomy and choice in healthcare within the specific context of self-testing devices. A growing number of self-testing medical devices are currently available for home use. The premise underpinning many of these devices is that they assist individuals to be more autonomous in the assessment and management of their health. Increased patient autonomy is assumed to be a good thing. We take issue with this assumption and argue that self-testing provides a specific example how increased patient autonomy and choice within healthcare might not best serve the patient population. We propose that current interpretations of autonomy in healthcare are based on negative accounts of liberty to the detriment of a more relational understanding. We also propose that Kantian philosophy is often applied to the healthcare arena in an inappropriate manner. We draw on the philosophical literature and examples from the self-testing process to support these claims. We conclude by offering an alternative account of autonomy based on the interrelated concepts of relationality, care and responsibility.

Developing public policy to advance the use of big data in health care.

PubMed

Heitmueller, Axel; Henderson, Sarah; Warburton, Will; Elmagarmid, Ahmed; Pentland, Alex Sandy; Darzi, Ara

2014-09-01

The vast amount of health data generated and stored around the world each day offers significant opportunities for advances such as the real-time tracking of diseases, predicting disease outbreaks, and developing health care that is truly personalized. However, capturing, analyzing, and sharing health data is difficult, expensive, and controversial. This article explores four central questions that policy makers should consider when developing public policy for the use of "big data" in health care. We discuss what aspects of big data are most relevant for health care and present a taxonomy of data types and levels of access. We suggest that successful policies require clear objectives and provide examples, discuss barriers to achieving policy objectives based on a recent policy experiment in the United Kingdom, and propose levers that policy makers should consider using to advance data sharing. We argue that the case for data sharing can be won only by providing real-life examples of the ways in which it can improve health care. Project HOPE—The People-to-People Health Foundation, Inc.

Causal Models for Mediation Analysis: An Introduction to Structural Mean Models.

PubMed

Zheng, Cheng; Atkins, David C; Zhou, Xiao-Hua; Rhew, Isaac C

2015-01-01

Mediation analyses are critical to understanding why behavioral interventions work. To yield a causal interpretation, common mediation approaches must make an assumption of "sequential ignorability." The current article describes an alternative approach to causal mediation called structural mean models (SMMs). A specific SMM called a rank-preserving model (RPM) is introduced in the context of an applied example. Particular attention is given to the assumptions of both approaches to mediation. Applying both mediation approaches to the college student drinking data yield notable differences in the magnitude of effects. Simulated examples reveal instances in which the traditional approach can yield strongly biased results, whereas the RPM approach remains unbiased in these cases. At the same time, the RPM approach has its own assumptions that must be met for correct inference, such as the existence of a covariate that strongly moderates the effect of the intervention on the mediator and no unmeasured confounders that also serve as a moderator of the effect of the intervention or the mediator on the outcome. The RPM approach to mediation offers an alternative way to perform mediation analysis when there may be unmeasured confounders.

Teaching Thousands with Cloud-based GIS

NASA Astrophysics Data System (ADS)

Gould, Michael; DiBiase, David; Beale, Linda

2016-04-01

Teaching Thousands with Cloud-based GIS Educators often draw a distinction between "teaching about GIS" and "teaching with GIS." Teaching about GIS involves helping students learn what GIS is, what it does, and how it works. On the other hand, teaching with GIS involves using the technology as a means to achieve education objectives in the sciences, social sciences, professional disciplines like engineering and planning, and even the humanities. The same distinction applies to CyberGIS. Understandably, early efforts to develop CyberGIS curricula and educational resources tend to be concerned primarily with CyberGIS itself. However, if CyberGIS becomes as functional, usable and scalable as it aspires to be, teaching with CyberGIS has the potential to enable large and diverse global audiences to perform spatial analysis using hosted data, mapping and analysis services all running in the cloud. Early examples of teaching tens of thousands of students across the globe with cloud-based GIS include the massive open online courses (MOOCs) offered by Penn State University and others, as well as the series of MOOCs more recently developed and offered by Esri. In each case, ArcGIS Online was used to help students achieve educational objectives in subjects like business, geodesign, geospatial intelligence, and spatial analysis, as well as mapping. Feedback from the more than 100,000 total student participants to date, as well as from the educators and staff who supported these offerings, suggest that online education with cloud-based GIS is scalable to very large audiences. Lessons learned from the course design, development, and delivery of these early examples may be useful in informing the continuing development of CyberGIS education. While MOOCs may have passed the peak of their "hype cycle" in higher education, the phenomenon they revealed persists: namely, a global mass market of educated young adults who turn to free online education to expand their horizons. The ability of CyberGIS to attract and effectively serve this market may be one measure of its success.

Development of Palliative Care in China: A Tale of Three Cities.

PubMed

Yin, Zhenyu; Li, Jinxiang; Ma, Ke; Ning, Xiaohong; Chen, Huiping; Fu, Haiyan; Zhang, Haibo; Wang, Chun; Bruera, Eduardo; Hui, David

2017-11-01

China is the most populous country in the world, but access to palliative care is extremely limited. A better understanding of the development of palliative care programs in China and how they overcome the barriers to provide services would inform how we can further integrate palliative care into oncology practices in China. Here, we describe the program development and infrastructure of the palliative care programs at three Chinese institutions, using these as examples to discuss strategies to accelerate palliative care access for cancer patients in China. Case study of three palliative care programs in Chengdu, Kunming, and Beijing. The three examples of palliative care delivery in China ranged from a comprehensive program that includes all major branches of palliative care in Chengdu, a program that is predominantly inpatient-based in Kunming, and a smaller program at an earlier stage of development in Beijing. Despite the numerous challenges related to the limited training opportunities, stigma on death and dying, and lack of resources and policies to support clinical practice, these programs were able to overcome many barriers to offer palliative care services to patients with advanced diseases and to advance this discipline in China through visionary leadership, collaboration with other countries to acquire palliative care expertise, committed staff members, and persistence. Palliative care is limited in China, although a few comprehensive programs exist. Our findings may inform palliative care program development in other Chinese hospitals. With a population of 1.3 billion, China is the most populous country in the world, and cancer is the leading cause of death. However, only 0.7% of hospitals offer palliative care services, which significantly limits palliative care access for Chinese cancer patients. Here, we describe the program development and infrastructure of three palliative care programs in China, using these as examples to discuss how they were able to overcome various barriers to implement palliative care. Lessons from these programs may help to accelerate the progress of palliative cancer care in China. © AlphaMed Press 2017.

Case-Based Learning with Worked Examples in Complex Domains: Two Experimental Studies in Undergraduate Medical Education

ERIC Educational Resources Information Center

Stark, Robin; Kopp, Veronika; Fischer, Martin R.

2011-01-01

To investigate the effects of example format (erroneous examples vs. correct examples) and feedback format (elaborated feedback vs. knowledge of results feedback) on medical students' diagnostic competence in the context of a web-based learning environment containing case-based worked examples, two studies with a 2 x 2 design were conducted in the…

Re-Framing Race in Teaching Writing across the Curriculum

ERIC Educational Resources Information Center

Poe, Mya

2013-01-01

Although faculty across the curriculum are often faced with issues of racial identity in the teaching of writing, WAC has offered little support for addressing race in assignment design, classroom interactions, and assessment. Through examples from teaching workshops, I offer specific ways that we can engage discussions about teaching writing and…

Fostering Academic Creativity in Gifted Students. ERIC Digest #E484.

ERIC Educational Resources Information Center

Torrance, E. Paul; Goff, Kathy

This digest describes academic creativity and offers suggestions for its development in gifted students. Creative learning and learning by authority are contrasted and examples of each are given. The naturally creative behavior of young children is noted. Among suggestions offered to teachers are: respect the unusual questions of children; show…

General Education Today. A Critical Analysis of Controversies, Practices, and Reforms.

ERIC Educational Resources Information Center

Gaff, Jerry G.

The range of controversies and changes emerging from the current revival of general education are examined, and many ideas, examples, and recommendations for achieving realistic and successful curricular reform are offered. Instead of either offering an apology for general education or advocating any particular approach, the book draws on solid…

Lessons learned from the Apple stores.

PubMed

Pinkney, Henry; Baum, Neil

2012-01-01

Medical practices have an opportunity to improve the services that they offer their patients. Practices can look at other businesses and industries for examples of outstanding customer service. This article will discuss the services provided by Apple, Inc., and how medical practices can learn from this industry giant and improve the services that they offer patients.

16 CFR 254.7 - Deceptive sales practices.

Code of Federal Regulations, 2010 CFR

2010-01-01

... implication, that employment is being offered or that a talent hunt or contest is being conducted. For example, captions such as, “Men/women wanted to train for * * *,” “Help Wanted,” “Employment,” “Business Opportunities,” and words or terms of similar import, may falsely convey that employment is being offered and...

16 CFR 254.7 - Deceptive sales practices.

Code of Federal Regulations, 2011 CFR

2011-01-01

... implication, that employment is being offered or that a talent hunt or contest is being conducted. For example, captions such as, “Men/women wanted to train for * * *,” “Help Wanted,” “Employment,” “Business Opportunities,” and words or terms of similar import, may falsely convey that employment is being offered and...

48 CFR 25.504-3 - FTA/Israeli Trade Act.

Code of Federal Regulations, 2014 CFR

2014-10-01

... 48 Federal Acquisition Regulations System 1 2014-10-01 2014-10-01 false FTA/Israeli Trade Act. 25.504-3 Section 25.504-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Evaluating Foreign Offers-Supply Contracts 25.504-3 FTA/Israeli Trade Act. (a) Example 1. Offer A $105,000...

48 CFR 25.504-3 - FTA/Israeli Trade Act.

Code of Federal Regulations, 2010 CFR

2010-10-01

... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false FTA/Israeli Trade Act. 25.504-3 Section 25.504-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Evaluating Foreign Offers-Supply Contracts 25.504-3 FTA/Israeli Trade Act. (a) Example 1. Offer A $105,000...

48 CFR 25.504-3 - FTA/Israeli Trade Act.

Code of Federal Regulations, 2011 CFR

2011-10-01

... 48 Federal Acquisition Regulations System 1 2011-10-01 2011-10-01 false FTA/Israeli Trade Act. 25.504-3 Section 25.504-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Evaluating Foreign Offers-Supply Contracts 25.504-3 FTA/Israeli Trade Act. (a) Example 1. Offer A $105,000...

48 CFR 25.504-3 - FTA/Israeli Trade Act.

Code of Federal Regulations, 2013 CFR

2013-10-01

... 48 Federal Acquisition Regulations System 1 2013-10-01 2013-10-01 false FTA/Israeli Trade Act. 25.504-3 Section 25.504-3 Federal Acquisition Regulations System FEDERAL ACQUISITION REGULATION SOCIOECONOMIC PROGRAMS FOREIGN ACQUISITION Evaluating Foreign Offers-Supply Contracts 25.504-3 FTA/Israeli Trade Act. (a) Example 1. Offer A $105,000...

Coming of Age: The Advanced Writing Curriculum [and CD-ROM]. CrossCurrents.

ERIC Educational Resources Information Center

Shamoon, Linda K., Ed.; Howard, Rebecca Moore, Ed.; Jamieson, Sandra, Ed.; Schwegler, Robert A., Ed.

Part book, part CD-ROM, this publication offers new ideas for transforming advanced writing courses. The 33 essays in the publication describe and offer concrete examples of curriculum that incorporates discipline-based theory and history, that situates writers in public discourse, and that fully prepares students for careers as writers. The…

Professional Development in Teaching and Learning for Early Career Academic Geographers: Contexts, Practices and Tensions

ERIC Educational Resources Information Center

Vajoczki, Susan; Biegas, Tamara C.; Crenshaw, Melody; Healey, Ruth L.; Osayomi, Tolulope; Bradford, Michael; Monk, Janice

2011-01-01

This paper provides a review of the practices and tensions informing approaches to professional development for early career academic geographers who are teaching in higher education. We offer examples from Britain, Canada, Nigeria and the USA. The tensions include: institutional and departmental cultures; models that offer generic and…

Science/Technology/Society. Focus on Excellence, Volume 1, Number 5.

ERIC Educational Resources Information Center

Penick, John E., Ed.; Meinhard-Pellens, Richard, Ed.

This document describes 10 examples of innovative and outstanding science/technology/society (STS) programs. These programs were selected using state criteria and at least four independent reviewers. While Project Synthesis offered a desired state, these examples of excellence provided views of what is already a reality. The goals of an exemplary…

29 CFR 2590.715-2704 - Prohibition of preexisting condition exclusions.

Code of Federal Regulations, 2010 CFR

2010-07-01

... exclusions—(1) In general. A group health plan, or a health insurance issuer offering group health insurance... examples illustrating the definition of a preexisting condition exclusion, see § 2590.701-3(a)(1)(ii) of this part): Example 1. (i) Facts. A group health plan provides benefits solely through an insurance...

Intuitive Ethics: Understanding and Critiquing the Role of Intuition in Ethical Decisions.

ERIC Educational Resources Information Center

Faber, Brenton

1999-01-01

Examines the role intuition plays in forming ethical decisions. Reviews examples of intuitive ethics in professional-communication research. Suggests that intuition is the naturalization of dominant cultural values and beliefs. Offers a pedagogical example of the theory and concludes by suggesting the value that a "critique of intuition"…

Effects of fabrication methods on spin relaxation and crystallite quality in Tm-doped ? powders studied using spectral hole burning

NASA Astrophysics Data System (ADS)

Lutz, Thomas; Veissier, Lucile; Thiel, Charles W.; Woodburn, Philip J. T.; Cone, Rufus L.; Barclay, Paul E.; Tittel, Wolfgang

2016-01-01

High-quality rare-earth-ion (REI) doped materials are a prerequisite for many applications such as quantum memories, ultra-high-resolution optical spectrum analyzers and information processing. Compared to bulk materials, REI doped powders offer low-cost fabrication and a greater range of accessible material systems. Here we show that crystal properties, such as nuclear spin lifetime, are strongly affected by mechanical treatment, and that spectral hole burning can serve as a sensitive method to characterize the quality of REI doped powders. We focus on the specific case of thulium doped ? (Tm:YAG). Different methods for obtaining the powders are compared and the influence of annealing on the spectroscopic quality of powders is investigated on a few examples. We conclude that annealing can reverse some detrimental effects of powder fabrication and, in certain cases, the properties of the bulk material can be reached. Our results may be applicable to other impurities and other crystals, including color centers in nano-structured diamond.

[Who is the guardian of our own health? Individual and social responsibility for health].

PubMed

Puyol, Angel

2014-10-01

Most people believe they have a duty to promote and protect the health of the population and treating the sick in case of medical need. And many also believe each person have a responsibility to his/her own health. Both beliefs can lead to a conflict of values with social and political implications. If people sick from individual choices (or unhealthy lifestyles), should we offer them a lower priority in access to health resources? The most popular example to refer to this situation is that of the diseases associated with smoking, but it is extensible to any disease that originates in a voluntary choice of the patient, as the abandonment of the medication, the practice of sport or unsafe sex, or the lack of preventive measures against influenza. In such cases, does social responsibility still prevail? My answer is yes. In this article, I argue that social responsibility for the health of the population prevails even if morally can and must empower people about their health.

Harm and the Boundaries of Disease.

PubMed

McGivern, Patrick; Sorial, Sarah

2017-08-01

What is the relationship between harm and disease? Discussions of the relationship between harm and disease typically suffer from two shortcomings. First, they offer relatively little analysis of the concept of harm itself, focusing instead on examples of clear cases of harm such as death and dismemberment. This makes it difficult to evaluate such accounts in borderline cases, where the putative harms are less severe. Second, they assume that harm-based accounts of disease must be understood normatively rather than naturalistically, in the sense that they are inherently value based. This makes such accounts vulnerable to more general objections of normative accounts of disease. Here we draw on an influential account of harm from the philosophy of law to develop a harm-based account of disease that overcomes both of these shortcomings. © The Author 2017. Published by Oxford University Press, on behalf of the Journal of Medicine and Philosophy Inc. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Risk and supervised exercise: the example of anorexia to illustrate a new ethical issue in the traditional debates of medical ethics

PubMed Central

Giordano, S

2005-01-01

Sport and physical activity is an area that remains relatively unexplored by contemporary bioethics. It is, however, an area in which important ethical issues arise. This paper explores the case of the participation of people with anorexia nervosa in exercise. Exercise is one of the central features of anorexia. The presence of anorexics in exercise classes is becoming an increasingly sensitive issue for instructors and fitness professionals. The ethics of teaching exercise to anorexics has, however, seldom, if ever, been addressed. Codes of ethics and legislation do not offer guidelines pertinent to the case and it is left unclear whether anorexics should be allowed to participate in exercise classes. It is shown by this paper that there are strong ethical reasons to let anorexics participate in exercise classes. However, the paper also explains why, despite these apparently cogent ethical reasons, there is no moral obligation to allow a person with anorexia to take part in exercise/sports activities. PMID:15634747

A delicate subject: The impact of cultural factors on neonatal and perinatal decision making.

PubMed

Van McCrary, S; Green, H C; Combs, A; Mintzer, J P; Quirk, J G

2014-01-01

The neonatal intensive care unit (NICU) is a high-stress environment for both families and health care providers that can sometimes make appropriate medical decisions challenging. We present a review article of non-medical barriers to effective decision making in the NICU, including: miscommunication, mixed messages, denial, comparative social and cultural influences, and the possible influence of perceived legal issues and family reliance on information from the Internet. As examples of these barriers, we describe and discuss two cases that occurred simultaneously in the same NICU where decisions were influenced by social and cultural differences that were misunderstood by both medical staff and patients' families. The resulting stress and emotional discomfort created an environment with sub-optimal relationships between patients' families and health care providers. We provide background on the sources of conflict in these particular cases. We also offer suggestions for possible amelioration of similar conflicts with the twin goals of facilitating compassionate decision making in NICU settings and promoting enhanced well-being of both families and providers.

Stranger than fiction: literary and clinical amnesia.

PubMed

Dieguez, Sebastian; Annoni, Jean-Marie

2013-01-01

This chapter broadly covers literary uses of amnesia and memory disorders. Amnesia in fiction offers authors an efficient and dramatic device to tackle themes such as identity, personal liberty, or guilt. We argue against the common complaint that fictional amnesia is scientifically inaccurate, pointing out that the goals of literature are different from those of science, that amnesia is still poorly understood, and that real-life cases can sometimes be stranger than fiction. The chapter provides examples from the neuropsychological literature, media reports, mythology, historical cases, detective stories, war stories, theatrical plays, and other genres. Special attention is given to retrograde and dissociative amnesia, as these are the most frequent types of amnesia portrayed in fiction, while other types of memory disorders are more shortly treated. We argue that the predominance of disorders affecting autobiographical memory in fiction is in itself a revealing fact about the mechanisms of human memory, illustrating how fictional treatments of pathology can inform back neurological and psychological research. Copyright © 2013 S. Karger AG, Basel.

Narrating practice: reflective accounts and the textual construction of reality.

PubMed

Taylor, Carolyn

2003-05-01

Two approaches dominate current thinking in health and welfare: evidence-based practice and reflective practice. Whilst there is debate about the merits of evidence-based practice, reflective practice is generally accepted with critical debate as an important educational tool. Where critique does exist it tends to adopt a Foucauldian approach, focusing on the surveillance and self-regulatory aspects of reflective practice. This article acknowledges the critical purchase on the concept of reflective practice offered by Foucauldian approaches but argues that microsociological and discourse analytic approaches can further illuminate the subject and thus serve as a complement to them. The claims of proponents of reflective practice are explored, in opposition to the technical-rational approach of evidence-based practice. Reflective practice tends to adopt a naive or romantic realist position and fails to acknowledge the ways in which reflective accounts construct the world of practice. Microsociological approaches can help us to understand reflective accounts as examples of case-talk, constructed in a narrative form in the same way as case records and presentations.

BioXSD: the common data-exchange format for everyday bioinformatics web services

PubMed Central

Kalaš, Matúš; Puntervoll, Pæl; Joseph, Alexandre; Bartaševičiūtė, Edita; Töpfer, Armin; Venkataraman, Prabakar; Pettifer, Steve; Bryne, Jan Christian; Ison, Jon; Blanchet, Christophe; Rapacki, Kristoffer; Jonassen, Inge

2010-01-01

Motivation: The world-wide community of life scientists has access to a large number of public bioinformatics databases and tools, which are developed and deployed using diverse technologies and designs. More and more of the resources offer programmatic web-service interface. However, efficient use of the resources is hampered by the lack of widely used, standard data-exchange formats for the basic, everyday bioinformatics data types. Results: BioXSD has been developed as a candidate for standard, canonical exchange format for basic bioinformatics data. BioXSD is represented by a dedicated XML Schema and defines syntax for biological sequences, sequence annotations, alignments and references to resources. We have adapted a set of web services to use BioXSD as the input and output format, and implemented a test-case workflow. This demonstrates that the approach is feasible and provides smooth interoperability. Semantics for BioXSD is provided by annotation with the EDAM ontology. We discuss in a separate section how BioXSD relates to other initiatives and approaches, including existing standards and the Semantic Web. Availability: The BioXSD 1.0 XML Schema is freely available at http://www.bioxsd.org/BioXSD-1.0.xsd under the Creative Commons BY-ND 3.0 license. The http://bioxsd.org web page offers documentation, examples of data in BioXSD format, example workflows with source codes in common programming languages, an updated list of compatible web services and tools and a repository of feature requests from the community. Contact: matus.kalas@bccs.uib.no; developers@bioxsd.org; support@bioxsd.org PMID:20823319

Ensembles generated from crystal structures of single distant homologues solve challenging molecular-replacement cases in AMPLE.

PubMed

Rigden, Daniel J; Thomas, Jens M H; Simkovic, Felix; Simpkin, Adam; Winn, Martyn D; Mayans, Olga; Keegan, Ronan M

2018-03-01

Molecular replacement (MR) is the predominant route to solution of the phase problem in macromolecular crystallography. Although routine in many cases, it becomes more effortful and often impossible when the available experimental structures typically used as search models are only distantly homologous to the target. Nevertheless, with current powerful MR software, relatively small core structures shared between the target and known structure, of 20-40% of the overall structure for example, can succeed as search models where they can be isolated. Manual sculpting of such small structural cores is rarely attempted and is dependent on the crystallographer's expertise and understanding of the protein family in question. Automated search-model editing has previously been performed on the basis of sequence alignment, in order to eliminate, for example, side chains or loops that are not present in the target, or on the basis of structural features (e.g. solvent accessibility) or crystallographic parameters (e.g. B factors). Here, based on recent work demonstrating a correlation between evolutionary conservation and protein rigidity/packing, novel automated ways to derive edited search models from a given distant homologue over a range of sizes are presented. A variety of structure-based metrics, many readily obtained from online webservers, can be fed to the MR pipeline AMPLE to produce search models that succeed with a set of test cases where expertly manually edited comparators, further processed in diverse ways with MrBUMP, fail. Further significant performance gains result when the structure-based distance geometry method CONCOORD is used to generate ensembles from the distant homologue. To our knowledge, this is the first such approach whereby a single structure is meaningfully transformed into an ensemble for the purposes of MR. Additional cases further demonstrate the advantages of the approach. CONCOORD is freely available and computationally inexpensive, so these novel methods offer readily available new routes to solve difficult MR cases.

Ensembles generated from crystal structures of single distant homologues solve challenging molecular-replacement cases in AMPLE

PubMed Central

Simpkin, Adam; Mayans, Olga; Keegan, Ronan M.

2018-01-01

Molecular replacement (MR) is the predominant route to solution of the phase problem in macromolecular crystallography. Although routine in many cases, it becomes more effortful and often impossible when the available experimental structures typically used as search models are only distantly homologous to the target. Nevertheless, with current powerful MR software, relatively small core structures shared between the target and known structure, of 20–40% of the overall structure for example, can succeed as search models where they can be isolated. Manual sculpting of such small structural cores is rarely attempted and is dependent on the crystallographer’s expertise and understanding of the protein family in question. Automated search-model editing has previously been performed on the basis of sequence alignment, in order to eliminate, for example, side chains or loops that are not present in the target, or on the basis of structural features (e.g. solvent accessibility) or crystallographic parameters (e.g. B factors). Here, based on recent work demonstrating a correlation between evolutionary conservation and protein rigidity/packing, novel automated ways to derive edited search models from a given distant homologue over a range of sizes are presented. A variety of structure-based metrics, many readily obtained from online webservers, can be fed to the MR pipeline AMPLE to produce search models that succeed with a set of test cases where expertly manually edited comparators, further processed in diverse ways with MrBUMP, fail. Further significant performance gains result when the structure-based distance geometry method CONCOORD is used to generate ensembles from the distant homologue. To our knowledge, this is the first such approach whereby a single structure is meaningfully transformed into an ensemble for the purposes of MR. Additional cases further demonstrate the advantages of the approach. CONCOORD is freely available and computationally inexpensive, so these novel methods offer readily available new routes to solve difficult MR cases. PMID:29533226

Worked Examples Leads to Better Performance in Analyzing and Solving Real-Life Decision Cases

ERIC Educational Resources Information Center

Cevik, Yasemin Demiraslan; Andre, Thomas

2012-01-01

This study compared the impact of three types of case-based methods (worked example, faded worked example, and case-based reasoning) on preservice teachers' (n=71) decision making and reasoning related to realistic classroom management situations. Participants in this study received a short-term implementation of one of these three major…

Medical Information Management System (MIMS): A generalized interactive information system

NASA Technical Reports Server (NTRS)

Alterescu, S.; Friedman, C. A.; Hipkins, K. R.

1975-01-01

An interactive information system is described. It is a general purpose, free format system which offers immediate assistance where manipulation of large data bases is required. The medical area is a prime area of application. Examples of the system's operation, commentary on the examples, and a complete listing of the system program are included.

Violence in the Schools: Programs and Policies for Prevention. A Report from the Canadian Education Association.

ERIC Educational Resources Information Center

MacDougall, Jyl

This publication offers some insight into the problem of violence in Canadian schools and provides examples of ways to reduce it. The forms of violent activities examined include youth/youth-gang violence, violence against teachers, bullying, sexual harassment, and sexual assault. Each chapter presents research findings and examples of programs…

Pattern-Forming Instabilities: A Phenomenological Approach through Simple Examples

ERIC Educational Resources Information Center

Brunet, Philippe

2007-01-01

From the streets of clouds to the submarine sand ripples or the striations on the coats of some animals, nature offers many examples of spontaneous patterned structures originating from various instabilities. These patterns can in turn destabilize and show a rich, complex dynamics and possibly end up in disordered behaviours. For over 20 years,…

Orchestrating Policy Ideas: Philanthropies and Think Tanks in US Education Policy Advocacy Networks

ERIC Educational Resources Information Center

Lubienski, Christopher; Brewer, T. Jameson; La Londe, Priya Goel

2016-01-01

While think tanks are a global phenomenon, their role in shaping US policy offers an instructive example of think tank influence on policymaking due to the immensity of resources directed towards those ends, with education policy serving as a prime example. Focusing on a distinct set of "incentivist" education policies, this analysis…

Reconstruction of disease transmission rates: Applications to measles, dengue, and influenza.

PubMed

Lange, Alexander

2016-07-07

Transmission rates are key in understanding the spread of infectious diseases. Using the framework of compartmental models, we introduce a simple method to reconstruct time series of transmission rates directly from incidence or disease-related mortality data. The reconstruction employs differential equations, which model the time evolution of infective stages and strains. Being sensitive to initial values, the method produces asymptotically correct solutions. The computations are fast, with time complexity being quadratic. We apply the reconstruction to data of measles (England and Wales, 1948-1967), dengue (Thailand, 1982-1999), and influenza (U.S., 1910-1927). The Measles example offers comparison with earlier work. Here we re-investigate reporting corrections, include and exclude demographic information. The dengue example deals with the failure of vector-control measures in reducing dengue hemorrhagic fever (DHF) in Thailand. Two competing mechanisms have been held responsible: strain interaction and demographic transitions. Our reconstruction reveals that both explanations are possible, showing that the increase in DHF cases is consistent with decreasing transmission rates resulting from reduced vector counts. The flu example focuses on the 1918/1919 pandemic, examining the transmission rate evolution for an invading strain. Our analysis indicates that the pandemic strain could have circulated in the population for many months before the pandemic was initiated by an event of highly increased transmission. Copyright © 2016 Elsevier Ltd. All rights reserved.

Developing Interactive Exhibits with Scientists: Three Example Collaborations from the Life Sciences Collection at the Exploratorium.

PubMed

King, Denise; Ma, Joyce; Armendariz, Angela; Yu, Kristina

2018-04-25

Science museums have made a concerted effort to work with researchers to incorporate current scientific findings and practices into informal learning opportunities for museum visitors. Many of these efforts have focused on creating opportunities and support for researchers to interact face-to-face with the public through, for example, speaker series, community forums, and engineering competitions. However, there are other means by which practicing scientists can find a voice on the museum floor - through the design and development of exhibits. Here we describe how researchers and museum professionals have worked together to create innovative exhibit experiences for an interactive science museum. For each example: scientist as (1) data providers, (2) advisors, and (3) co-developers, we highlight essential components for a successful partnership and pitfalls to avoid when collaborating on museum exhibits. Not many museums prototype and build their own exhibits like the Exploratorium. In those cases, there may be similar opportunities in more mediated offerings such as public demonstrations or lectures or in other formats that allow for direct interactions between scientists and visitors.We believe there are many opportunities for researchers to share natural phenomena, to advise on exhibit development and interpretation, to provide much needed materials, and to otherwise incorporate authentic research into the learning experiences at museums, no matter what the format.

Comparative effectiveness regulations and pharmaceutical innovation.

PubMed

Vernon, John A; Golec, Joseph H; Stevens, J Stedman

2010-01-01

As healthcare reform evolves and takes shape, comparative effectiveness research (CER) appears to be one of the central topics on the national healthcare agenda. Over the past couple of years, comparative effectiveness has been explicitly incorporated in more than ten bills. For example, the passage of the American Recovery and Reinvestment Act of 2009 authorized $US1.1 billion for CER. Comparative effectiveness, when costs are formally considered, offers the hope of efficient resource allocation within US healthcare markets. However, the future operationalization and implementation of comparative effectiveness is uncertain, and there exist potentially negative, and unintended, consequences under certain scenarios. One example, and the focus of this article, is pharmaceutical innovation. Incentives for pharmaceutical R&D could be affected if drug development costs increase as a result of firms having to bear, directly or indirectly, the costs of running larger, randomized, head-to-head comparative effectiveness trials. While this may or may not be the case with current and future comparative effectiveness legislation and its subsequent implementation, the potential consequences for pharmaceutical innovation warrant recognition. This is the purpose of the article. To achieve this goal, we develop several models of clinical trial design, drug development costs and R&D investment. By example, we shed light on the causal links between the models and the ways in which industry R&D investment can be affected.

Time perception: the bad news and the good

PubMed Central

Matthews, William J; Meck, Warren H

2014-01-01

Time perception is fundamental and heavily researched, but the field faces a number of obstacles to theoretical progress. In this advanced review, we focus on three pieces of ‘bad news’ for time perception research: temporal perception is highly labile across changes in experimental context and task; there are pronounced individual differences not just in overall performance but in the use of different timing strategies and the effect of key variables; and laboratory studies typically bear little relation to timing in the ‘real world’. We describe recent examples of these issues and in each case offer some ‘good news’ by showing how new research is addressing these challenges to provide rich insights into the neural and information-processing bases of timing and time perception. PMID:25210578

HIV/AIDS, social capital, and online social networks.

PubMed

Drushel, Bruce E

2013-01-01

The prospects for online social networks as sites of information-gathering and affiliation for persons with AIDS and others concerned about HIV/AIDS not only represent the latest development in a trend toward circumventing traditional media and official information sources, but also may offer hope for a revitalization of HIV/AIDS discourse in the public sphere. This article provides an overview of three decades of information-seeking on the pandemic and its social and personal implications, as well as case studies of three examples of social networking surrounding HIV/AIDS. It finds preliminary evidence of the formation of strong and weak ties as described in Social Network Theory and suggests that the online accumulation of social capital by opinion leaders could facilitate dissemination of messages on HIV/AIDS awareness and testing.

[Invisible and almost invisible orthodontic appliances].

PubMed

Baron, Pascal

2014-03-01

Patient demand for invisible esthetic orthodontic appliances is steadily increasing. Two types of orthodontic appliances have a high rate of patient acceptance. The lingual technique has continually evolved by offering both prefabricated brackets or custom-made brackets. The various techniques have been improved over time, and the results are better than ever. Thermoplastic aligners are an alternative to lingual devices and their use is rapidly growing. Their specific properties make it easier to assess their indications and limitations. A review of the literature, the development of these systems and a presentation of some clinical examples of treated cases will help us to provide some of the basics for understanding each of these two types of appliances and to demonstrate the advantages and disadvantages of each system. © EDP Sciences, SFODF, 2014.

Novel Routes for Improving Biocontrol Activity of Bacillus Based Bioinoculants

PubMed Central

Wu, Liming; Wu, Hui-Jun; Qiao, Junqing; Gao, Xuewen; Borriss, Rainer

2015-01-01

Biocontrol (BC) formulations prepared from plant-growth-promoting bacteria are increasingly applied in sustainable agriculture. Especially inoculants prepared from endospore-forming Bacillus strains have been proven as efficient and environmental-friendly alternative to chemical pesticides due to their long shelf life, which is comparable with that of agrochemicals. However, these formulations of the first generation are sometimes hampered in their action and do not fulfill in each case the expectations of the appliers. In this review we use the well-known plant-associated Bacillus amyloliquefaciens type strain FZB42 as example for the successful application of different techniques offered today by comparative, evolutionary and functional genomics, site-directed mutagenesis and strain construction including marker removal, for paving the way for preparing a novel generation of BC agents. PMID:26696998

A class of Box-Cox transformation models for recurrent event data.

PubMed

Sun, Liuquan; Tong, Xingwei; Zhou, Xian

2011-04-01

In this article, we propose a class of Box-Cox transformation models for recurrent event data, which includes the proportional means models as special cases. The new model offers great flexibility in formulating the effects of covariates on the mean functions of counting processes while leaving the stochastic structure completely unspecified. For the inference on the proposed models, we apply a profile pseudo-partial likelihood method to estimate the model parameters via estimating equation approaches and establish large sample properties of the estimators and examine its performance in moderate-sized samples through simulation studies. In addition, some graphical and numerical procedures are presented for model checking. An example of application on a set of multiple-infection data taken from a clinic study on chronic granulomatous disease (CGD) is also illustrated.

Does intuition have a role in psychiatric diagnosis?

PubMed

Srivastava, Anil; Grube, Michael

2009-06-01

Psychiatric diagnosis is invariably guided by self-report. When such self-report is questioned, reliance on formalized testing predominates. The situation is less certain, however, when such methods and clinical "feel", or intuition, conflict. While many argue for the supremacy of actuarial methods, fields such as Management have increasingly emphasized the importance of intuition; Psychiatry, although with few objective tests and reliance on the clinical encounter, offers surprisingly few answers. We explore here the use of intuition in decision-making through a case example and suggest that it is not inferior to other diagnostic methods: intuition should be used to suggest, guide, and modify psychiatric diagnosis. Mostly, there is a need for greater discussion among Psychiatrists including consideration to the clinical, legal, and ethical implications of the use of intuition in psychiatric decision-making.

Carbonate aquifers

USGS Publications Warehouse

Cunningham, Kevin J.; Sukop, Michael; Curran, H. Allen

2012-01-01

Only limited hydrogeological research has been conducted using ichnology in carbonate aquifer characterization. Regardless, important applications of ichnology to carbonate aquifer characterization include its use to distinguish and delineate depositional cycles, correlate mappable biogenically altered surfaces, identify zones of preferential groundwater flow and paleogroundwater flow, and better understand the origin of ichnofabric-related karst features. Three case studies, which include Pleistocene carbonate rocks of the Biscayne aquifer in southern Florida and Cretaceous carbonate strata of the Edwards–Trinity aquifer system in central Texas, demonstrate that (1) there can be a strong relation between ichnofabrics and groundwater flow in carbonate aquifers and (2) ichnology can offer a useful methodology for carbonate aquifer characterization. In these examples, zones of extremely permeable, ichnofabric-related macroporosity are mappable stratiform geobodies and as such can be represented in groundwater flow and transport simulations.

Negotiating for more: the multiple equivalent simultaneous offer.

PubMed

Heller, Richard E

2014-02-01

Whether a doctor, professional baseball manager, or a politician, having successful negotiation skills is a critical part of being a leader. Building upon prior journal articles on negotiation strategy, the author presents the concept of the multiple equivalent simultaneous offer (MESO). The concept of a MESO is straightforward: as opposed to making a single offer, make multiple offers with several variables. Each offer alters the different variables, such that the end result of each offer is equivalent from the perspective of the party making the offer. Research has found several advantages to the use of MESOs. For example, using MESOs, an offer was more likely to be accepted, and the counterparty was more likely to be satisfied with the negotiated deal. Additional benefits have been documented as well, underscoring why a prepared radiology business leader should understand the theory and practice of MESO. Copyright © 2014 American College of Radiology. Published by Elsevier Inc. All rights reserved.

Traditional Chinese Medicine as a Basis for Treating Psychiatric Disorders: A Review of Theory with Illustrative Cases

PubMed Central

Aung, Steven K.H.; Fay, Heather

2013-01-01

Abstract Background: Integrative medicine is becoming increasingly accepted in the global scheme of health care. Traditional Chinese Medicine (TCM) is often included among integrative medicine modalities. Objective: This article provides a background for integration of acupuncture and other TCM-derived approaches to managing psychiatric conditions. Methods: Classical theories of TCM that pertain to psychiatric conditions are reviewed, focusing on concepts of energetic imbalance, the implications of mind–body–spirit connections, and treatment strategies that involve TCM modalities. An example of correlation between TCM patterns of disharmony and the Western diagnosis of generalized anxiety disorder (GAD) is given, along with an illustrative case in which counseling, medications, and acupuncture were combined in treatment. TCM principles are incorporated in certain energy psychology modalities, such as Emotional Freedom Technique (EFT). A case is presented demonstrating the integration of energy psychology with acupuncture, Qigong and hypnosis as an avenue for releasing pathogenic emotions. In classical TCM theory, assessing and treating spiritual disharmonies is fundamental for dealing with emotional disorders. Practical application in a clinical case is described. Conclusions: TCM offers a cogent theoretical basis for assessing and clinically managing patients presenting with mental health issues. TCM principles integrate well with other systems, including Western medicine. PMID:24761185

Organizational values in the provision of access to care for the uninsured

PubMed Central

Harrison, Krista Lyn; Taylor, Holly A.

2017-01-01

Background For the last 20 years, health provider organizations have made efforts to align mission, values, and everyday practices to ensure high-quality, high-value, and ethical care. However, little attention has been paid to the organizational values and practices of community-based programs that organize and facilitate access to care for uninsured populations. This study aimed to identify and describe organizational values relevant to resource allocation and policy decisions that affect the services offered to members, using the case of community access programs: county-based programs that provide access to care for the uninsured working poor. Methods Comparative and qualitative case study methodology was used, including document review, observations, and key informant interviews, at two geographically diverse programs. Results Nine values were identified as relevant to decision making: stewardship, quality care, access to care, service to others, community well-being, member independence, organizational excellence, decency, and fairness. The way these values were deployed in resource allocation decisions that affected services offered to the uninsured are illustrated in one example per site. Conclusions This study addresses the previous dearth in the literature regarding an empirical description of organizational values employed in decision making of community organizations. To assess the transferability of the values identified, we compared our empirical results to prior empirical and conceptual work in the United States and internationally and found substantial alignment. Future studies can examine whether the identified organizational values are reflective of those at other health care organizations. PMID:28781981

Very-low-power and footprint integrated photonic modulators and switches for ICT

NASA Astrophysics Data System (ADS)

Thylén, Lars; Holmström, Petter; Wosinski, Lech

2013-03-01

The current development in photonics for communications and interconnects pose increasing requirements on reduction of footprint, power dissipation and cost, as well as increased bandwidth. Integrated nanophotonics has been viewed as one solution to this, capitalizing on development in nanotechnology as such as well as on increased insights into light matter interaction on the nanoscale. The latter can be exemplified by plasmonics and low-dimensional semiconductors such as quantum dots (QDs). In this scenario the development of better electrooptic materials is also of great importance, the electrooptic polymers being an example, since they potentially offer improved properties for optical phase modulators in terms of power and probably cost and general flexibility. Phase modulators are essential for e.g. the rapidly developing advanced modulation formats for telecom, since phase modulation basically can generate any type of modulation. The electrooptic polymers, e.g. in combination with plasmonics nanoparticle array waveguides or nanostructured hybrid plasmonic media can theoretically give extremely compact and low power dissipation modulators, still to be demonstrated. The low-dimensional semiconductors, e.g. in the shape of QDs, can be employed for modulation or switching functions, offering possibilities in the future for scaling to 2 or 3 dimensions for advanced switching functions. In both the plasmonics and QD cases, nanosizing and low power dissipation are generally due to near-field interactions, albeit being of different physical origin in the two cases. A comparison of all-optical and electronically controlled switching is given.

Validation of Satellite-Based Objective Overshooting Cloud-Top Detection Methods Using CloudSat Cloud Profiling Radar Observations

NASA Technical Reports Server (NTRS)

Bedka, Kristopher M.; Dworak, Richard; Brunner, Jason; Feltz, Wayne

2012-01-01

Two satellite infrared-based overshooting convective cloud-top (OT) detection methods have recently been described in the literature: 1) the 11-mm infrared window channel texture (IRW texture) method, which uses IRW channel brightness temperature (BT) spatial gradients and thresholds, and 2) the water vapor minus IRW BT difference (WV-IRW BTD). While both methods show good performance in published case study examples, it is important to quantitatively validate these methods relative to overshooting top events across the globe. Unfortunately, no overshooting top database currently exists that could be used in such study. This study examines National Aeronautics and Space Administration CloudSat Cloud Profiling Radar data to develop an OT detection validation database that is used to evaluate the IRW-texture and WV-IRW BTD OT detection methods. CloudSat data were manually examined over a 1.5-yr period to identify cases in which the cloud top penetrates above the tropopause height defined by a numerical weather prediction model and the surrounding cirrus anvil cloud top, producing 111 confirmed overshooting top events. When applied to Moderate Resolution Imaging Spectroradiometer (MODIS)-based Geostationary Operational Environmental Satellite-R Series (GOES-R) Advanced Baseline Imager proxy data, the IRW-texture (WV-IRW BTD) method offered a 76% (96%) probability of OT detection (POD) and 16% (81%) false-alarm ratio. Case study examples show that WV-IRW BTD.0 K identifies much of the deep convective cloud top, while the IRW-texture method focuses only on regions with a spatial scale near that of commonly observed OTs. The POD decreases by 20% when IRW-texture is applied to current geostationary imager data, highlighting the importance of imager spatial resolution for observing and detecting OT regions.

Twenty Years On!: Updating the IEA BESTEST Building Thermal Fabric Test Cases for ASHRAE Standard 140

DOE Office of Scientific and Technical Information (OSTI.GOV)

Judkoff, R.; Neymark, J.

2013-07-01

ANSI/ASHRAE Standard 140, Standard Method of Test for the Evaluation of Building Energy Analysis Computer Programs applies the IEA BESTEST building thermal fabric test cases and example simulation results originally published in 1995. These software accuracy test cases and their example simulation results, which comprise the first test suite adapted for the initial 2001 version of Standard 140, are approaching their 20th anniversary. In response to the evolution of the state of the art in building thermal fabric modeling since the test cases and example simulation results were developed, work is commencing to update the normative test specification and themore » informative example results.« less

Twenty Years On!: Updating the IEA BESTEST Building Thermal Fabric Test Cases for ASHRAE Standard 140: Preprint

DOE Office of Scientific and Technical Information (OSTI.GOV)

Judkoff, R.; Neymark, J.

2013-07-01

ANSI/ASHRAE Standard 140, Standard Method of Test for the Evaluation of Building Energy Analysis Computer Programs applies the IEA BESTEST building thermal fabric test cases and example simulation results originally published in 1995. These software accuracy test cases and their example simulation results, which comprise the first test suite adapted for the initial 2001 version of Standard 140, are approaching their 20th anniversary. In response to the evolution of the state of the art in building thermal fabric modeling since the test cases and example simulation results were developed, work is commencing to update the normative test specification and themore » informative example results.« less

28 CFR Appendix B to Part 36 - Preamble to Regulation on Nondiscrimination on the Basis of Disability by Public Accommodations...

Code of Federal Regulations, 2010 CFR

2010-07-01

... that limited his or her enjoyment of the goods or services being offered. For example, persons with.... It also applies, in accordance with section 309 of the ADA, to private entities that offer... relay services. Title IV of the Act provides adequate protections for ensuring the confidentiality of...

Creating Learning Communities: A Practical Guide to Winning Support, Organizing for Change, and Implementing Programs. Jossey-Bass Higher and Adult Education Series.

ERIC Educational Resources Information Center

Shapiro, Nancy S.; Levine, Jodi H.

This book offers guidance for the development of learning communities at the college level. The book analyzes examples of learning communities at a wide variety of institutions, including research universities, commuter campuses, residential campuses, and four- and two-year institutions. Chapter 1 offers definitions and characteristics of learning…

The Postmodern Educator: Arts-Based Inquiries and Teacher Development. Counterpoints: Studies in the Postmodern Theory of Education, Vol. 89.

ERIC Educational Resources Information Center

Diamond, C. T. Patrick, Ed.; Mullen, Carol A., Ed.

This collection offers research stories of teachers and teacher educators who explore their own artistic and analytic practices in many different settings. Divided into two parts, the collection examines why arts-based inquiry and teacher development are needed and offers examples of them. Following a prologue entitled "An Invitation to an…

What serious video games can offer child obesity prevention.

PubMed

Thompson, Debbe

2014-07-16

Childhood obesity is a worldwide issue, and effective methods encouraging children to adopt healthy diet and physical activity behaviors are needed. This viewpoint addresses the promise of serious video games, and why they may offer one method for helping children eat healthier and become more physically active. Lessons learned are provided, as well as examples gleaned from personal experiences.

Clinical review: Checklists - translating evidence into practice

PubMed Central

2009-01-01

Checklists are common tools used in many industries. Unfortunately, their adoption in the field of medicine has been limited to equipment operations or part of specific algorithms. Yet they have tremendous potential to improve patient outcomes by democratizing knowledge and helping ensure that all patients receive evidence-based best practices and safe high-quality care. Checklist adoption has been slowed by a variety of factors, including provider resistance, delays in knowledge dissemination and integration, limited methodology to guide development and maintenance, and lack of effective technical strategies to make them available and easy to use. In this article, we explore some of the principles and possible strategies to further develop and encourage the implementation of checklists into medical practice. We describe different types of checklists using examples and explore the benefits they offer to improve care. We suggest methods to create checklists and offer suggestions for how we might apply them, using some examples from our own experience, and finally, offer some possible directions for future research. PMID:20064195

When we give more: reflections on intangible gifts from therapist to patient.

PubMed

Smolar, Andrew I

2003-01-01

Since Freud's time, psychoanalytically oriented therapists have been wary of accepting gifts from patients, and have also been reluctant to give them to patients. This article first provides a literal definition of the word "gift," and then defines it within the context of the therapeutic relationship. It then reviews the literature on gifts and presents clinical examples describing five categories of offerings from therapist to patient, experienced by the patient as gifts, namely: 1. the gift of a transitional object; 2. the gift of self-disclosure; 3. the gift of time; 4. the gift of physical touch; and 5. the gift of developmental presence. Examples of therapists' considering but not offering gifts to patients are discussed and viewed from the perspective of whether they are requested by the patient, whether they arise from within the therapist, or whether they are offered in a context of reciprocation. Guidelines for how and when the therapist could attempt such interventions most safely are suggested, placing particular emphasis on counter-transferences.

Noncredit Continuing Education: Who Does what for Whom...and Why?

ERIC Educational Resources Information Center

Long, Norma R.

1988-01-01

A case study illustrates the need to examine criteria used to select noncredit continuing education offerings. In this case, the physics faculty protested that the offering "Fundamentals of Astrology" was inappropriate as a university noncredit course. A survey of 77 continuing education divisions revealed how course offering choices are made. (CH)

Example-Based Super-Resolution Fluorescence Microscopy.

PubMed

Jia, Shu; Han, Boran; Kutz, J Nathan

2018-04-23

Capturing biological dynamics with high spatiotemporal resolution demands the advancement in imaging technologies. Super-resolution fluorescence microscopy offers spatial resolution surpassing the diffraction limit to resolve near-molecular-level details. While various strategies have been reported to improve the temporal resolution of super-resolution imaging, all super-resolution techniques are still fundamentally limited by the trade-off associated with the longer image acquisition time that is needed to achieve higher spatial information. Here, we demonstrated an example-based, computational method that aims to obtain super-resolution images using conventional imaging without increasing the imaging time. With a low-resolution image input, the method provides an estimate of its super-resolution image based on an example database that contains super- and low-resolution image pairs of biological structures of interest. The computational imaging of cellular microtubules agrees approximately with the experimental super-resolution STORM results. This new approach may offer potential improvements in temporal resolution for experimental super-resolution fluorescence microscopy and provide a new path for large-data aided biomedical imaging.

Musings on privacy issues in health research involving disaggregate geographic data about individuals.

PubMed

Boulos, Maged N Kamel; Curtis, Andrew J; Abdelmalik, Philip

2009-07-20

This paper offers a state-of-the-art overview of the intertwined privacy, confidentiality, and security issues that are commonly encountered in health research involving disaggregate geographic data about individuals. Key definitions are provided, along with some examples of actual and potential security and confidentiality breaches and related incidents that captured mainstream media and public interest in recent months and years. The paper then goes on to present a brief survey of the research literature on location privacy/confidentiality concerns and on privacy-preserving solutions in conventional health research and beyond, touching on the emerging privacy issues associated with online consumer geoinformatics and location-based services. The 'missing ring' (in many treatments of the topic) of data security is also discussed. Personal information and privacy legislations in two countries, Canada and the UK, are covered, as well as some examples of recent research projects and events about the subject. Select highlights from a June 2009 URISA (Urban and Regional Information Systems Association) workshop entitled 'Protecting Privacy and Confidentiality of Geographic Data in Health Research' are then presented. The paper concludes by briefly charting the complexity of the domain and the many challenges associated with it, and proposing a novel, 'one stop shop' case-based reasoning framework to streamline the provision of clear and individualised guidance for the design and approval of new research projects (involving geographical identifiers about individuals), including crisp recommendations on which specific privacy-preserving solutions and approaches would be suitable in each case.

Harm is all you need? Best interests and disputes about parental decision-making

PubMed Central

Birchley, Giles

2016-01-01

A growing number of bioethics papers endorse the harm threshold when judging whether to override parental decisions. Among other claims, these papers argue that the harm threshold is easily understood by lay and professional audiences and correctly conforms to societal expectations of parents in regard to their children. English law contains a harm threshold which mediates the use of the best interests test in cases where a child may be removed from her parents. Using Diekema's seminal paper as an example, this paper explores the proposed workings of the harm threshold. I use examples from the practical use of the harm threshold in English law to argue that the harm threshold is an inadequate answer to the indeterminacy of the best interests test. I detail two criticisms: First, the harm standard has evaluative overtones and judges are loath to employ it where parental behaviour is misguided but they wish to treat parents sympathetically. Thus, by focusing only on ‘substandard’ parenting, harm is problematic where the parental attempts to benefit their child are misguided or wrong, such as in disputes about withdrawal of medical treatment. Second, when harm is used in genuine dilemmas, court judgments offer different answers to similar cases. This level of indeterminacy suggests that, in practice, the operation of the harm threshold would be indistinguishable from best interests. Since indeterminacy appears to be the greatest problem in elucidating what is best, bioethicists should concentrate on discovering the values that inform best interests. PMID:26401048

Musings on privacy issues in health research involving disaggregate geographic data about individuals

PubMed Central

Boulos, Maged N Kamel; Curtis, Andrew J; AbdelMalik, Philip

2009-01-01

This paper offers a state-of-the-art overview of the intertwined privacy, confidentiality, and security issues that are commonly encountered in health research involving disaggregate geographic data about individuals. Key definitions are provided, along with some examples of actual and potential security and confidentiality breaches and related incidents that captured mainstream media and public interest in recent months and years. The paper then goes on to present a brief survey of the research literature on location privacy/confidentiality concerns and on privacy-preserving solutions in conventional health research and beyond, touching on the emerging privacy issues associated with online consumer geoinformatics and location-based services. The 'missing ring' (in many treatments of the topic) of data security is also discussed. Personal information and privacy legislations in two countries, Canada and the UK, are covered, as well as some examples of recent research projects and events about the subject. Select highlights from a June 2009 URISA (Urban and Regional Information Systems Association) workshop entitled 'Protecting Privacy and Confidentiality of Geographic Data in Health Research' are then presented. The paper concludes by briefly charting the complexity of the domain and the many challenges associated with it, and proposing a novel, 'one stop shop' case-based reasoning framework to streamline the provision of clear and individualised guidance for the design and approval of new research projects (involving geographical identifiers about individuals), including crisp recommendations on which specific privacy-preserving solutions and approaches would be suitable in each case. PMID:19619311

The Social History of Open Education: Austrian and Soviet Schools in the 1920s

ERIC Educational Resources Information Center

Hein, George E.

1975-01-01

Discusses how open education arose in the United States, what its relations are to the society around it, and what it has to offer to the American scene by examining past attempts to institute it in two other countries, noting that the two examples each present graphic examples of the interrelationship between education and politics. (Author/JM)

Analyzing free fall with a smartphone acceleration sensor

NASA Astrophysics Data System (ADS)

Wogt, Patrik; Kuhn, Jochen

2012-03-01

This paper provides a first example of experiments in this column using smartphones as experimental tools. More examples concerning this special tool will follow in the next issues. The differences between a smartphone and a ``regular'' cell phone are that smartphones offer more advanced computing ability and connectivity. Smartphones combine the functions of personal digital assistants (PDAs) and cell phones.

Enabling Prosecutors To Address Drug, Gang, and Youth Violence. Juvenile Accountability Incentive Block Grants (JAIBG) Program Bulletin.

ERIC Educational Resources Information Center

Gramckow, Heike P.; Tompkins, Elena

This bulletin offers data on recent trends in juvenile violence, juvenile drug offenses, and gang-related juvenile offending, and describes prosecutorial responses to such offenses. Examples of promising prosecutor-led programs combating the illicit use of guns, violence, drugs, and gangs are also provided. These examples provide a range of ideas…

What do external consultants from private and not-for-profit companies offer healthcare commissioners? A qualitative study of knowledge exchange.

PubMed

Wye, Lesley; Brangan, Emer; Cameron, Ailsa; Gabbay, John; Klein, Jonathan H; Anthwal, Rachel; Pope, Catherine

2015-02-25

The use of external consultants from private and not-for-profit providers in the National Health Service (NHS) is intended to improve the quality of commissioning. The aim of this study was to learn about the support offered to healthcare commissioners, how external consultants and their clients work together and the perceived impact on the quality of commissioning. NHS commissioning organisations and private and not-for-profit providers. Mixed methods case study of eight cases. 92 interviews with external consultants (n=36), their clients (n=47) and others (n=9). Observation of 25 training events and meetings. Documentation, for example, meeting minutes and reports. Constant comparison. Data were coded, summarised and analysed by the research team with a coding framework to facilitate cross-case comparison. In the four contracts presented here, external providers offered technical solutions (eg, software tools), outsourcing and expertise including project management, data interpretation and brokering relationships with experts. In assessing perceived impact on quality of commissioning, two contracts had limited value, one had short-term benefits and one provided short and longer term benefits. Contracts with commissioners actively learning, embedding and applying new skills were more valued. Other elements of success were: (1) addressing clearly agreed problems of relevance to managerial and operational staff (2) solutions co-produced at all organisational levels (3) external consultants working directly with clients to interpret data outputs to inform locally contextualised commissioning strategies. Without explicit knowledge exchange strategies, outsourcing commissioning to external providers resulted in the NHS clients becoming dependent. NHS commissioning will be disadvantaged if commissioners both fail to learn in the short term from the knowledge of external providers and in the longer term lose local skills. Knowledge exchange mechanisms are a vital component of commissioning and should be embedded in external provider contracts. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Production Design: Holding It Together.

ERIC Educational Resources Information Center

Connelly, James O.

1994-01-01

Discusses production design for videos. Outlines general considerations (opening, transitions, content areas, and closing) and specific considerations (typography, screen design, music, and sound effects). Offers an example. (SR)

Non-traditional isotopes in analytical ecogeochemistry assessed by MC-ICP-MS

NASA Astrophysics Data System (ADS)

Prohaska, Thomas; Irrgeher, Johanna; Horsky, Monika; Hanousek, Ondřej; Zitek, Andreas

2014-05-01

Analytical ecogeochemistry deals with the development and application of tools of analytical chemistry to study dynamic biological and ecological processes within ecosystems and across ecosystem boundaries in time. It can be best described as a linkage between modern analytical chemistry and a holistic understanding of ecosystems ('The total human ecosystem') within the frame of transdisciplinary research. One focus of analytical ecogeochemistry is the advanced analysis of elements and isotopes in abiotic and biotic matrices and the application of the results to basic questions in different research fields like ecology, environmental science, climatology, anthropology, forensics, archaeometry and provenancing. With continuous instrumental developments, new isotopic systems have been recognized for their potential to study natural processes and well established systems could be analyzed with improved techniques, especially using multi collector inductively coupled plasma mass spectrometry (MC-ICP-MS). For example, in case of S, isotope ratio measurements at high mass resolution could be achieved at much lower S concentrations with ICP-MS as compared to IRMS, still keeping suitable uncertainty. Almost 50 different isotope systems have been investigated by ICP-MS, so far, with - besides Sr, Pb and U - Ca, Mg, Cd, Li, Hg, Si, Ge and B being the most prominent and considerably pushing the limits of plasma based mass spectrometry also by applying high mass resolution. The use of laser ablation in combination with MC-ICP-MS offers the possibility to achieve isotopic information on high spatial (µm-range) and temporal scale (in case of incrementally growing structures). The information gained with these analytical techniques can be linked between different hierarchical scales in ecosystems, offering means to better understand ecosystem processes. The presentation will highlight the use of different isotopic systems in ecosystem studies accomplished by ICP-MS. Selected examples on combining isotopic systems for the study of ecosystem processes on different spatial scales will underpin the great opportunities substantiated by the field of analytical ecogeochemistry. Moreover, recent developments in plasma mass spectrometry and the application of new isotopic systems require sound metrological approaches in order to prevent scientific conclusions drawn from analytical artifacts.

A nodal discontinuous Galerkin approach to 3-D viscoelastic wave propagation in complex geological media

NASA Astrophysics Data System (ADS)

Lambrecht, L.; Lamert, A.; Friederich, W.; Möller, T.; Boxberg, M. S.

2018-03-01

A nodal discontinuous Galerkin (NDG) approach is developed and implemented for the computation of viscoelastic wavefields in complex geological media. The NDG approach combines unstructured tetrahedral meshes with an element-wise, high-order spatial interpolation of the wavefield based on Lagrange polynomials. Numerical fluxes are computed from an exact solution of the heterogeneous Riemann problem. Our implementation offers capabilities for modelling viscoelastic wave propagation in 1-D, 2-D and 3-D settings of very different spatial scale with little logistical overhead. It allows the import of external tetrahedral meshes provided by independent meshing software and can be run in a parallel computing environment. Computation of adjoint wavefields and an interface for the computation of waveform sensitivity kernels are offered. The method is validated in 2-D and 3-D by comparison to analytical solutions and results from a spectral element method. The capabilities of the NDG method are demonstrated through a 3-D example case taken from tunnel seismics which considers high-frequency elastic wave propagation around a curved underground tunnel cutting through inclined and faulted sedimentary strata. The NDG method was coded into the open-source software package NEXD and is available from GitHub.

Expanding the eco-evolutionary context of herbicide resistance research.

PubMed

Neve, Paul; Busi, Roberto; Renton, Michael; Vila-Aiub, Martin M

2014-09-01

The potential for human-driven evolution in economically and environmentally important organisms in medicine, agriculture and conservation management is now widely recognised. The evolution of herbicide resistance in weeds is a classic example of rapid adaptation in the face of human-mediated selection. Management strategies that aim to slow or prevent the evolution of herbicide resistance must be informed by an understanding of the ecological and evolutionary factors that drive selection in weed populations. Here, we argue for a greater focus on the ultimate causes of selection for resistance in herbicide resistance studies. The emerging fields of eco-evolutionary dynamics and applied evolutionary biology offer a means to achieve this goal and to consider herbicide resistance in a broader and sometimes novel context. Four relevant research questions are presented, which examine (i) the impact of herbicide dose on selection for resistance, (ii) plant fitness in herbicide resistance studies, (iii) the efficacy of herbicide rotations and mixtures and (iv) the impacts of gene flow on resistance evolution and spread. In all cases, fundamental ecology and evolution have the potential to offer new insights into herbicide resistance evolution and management. © 2014 Society of Chemical Industry.

Grief and mourning in schizophrenia.

PubMed

Wittmann, Daniela; Keshavan, Matcheri

2007-01-01

Depression and suicidality after first episode of psychosis are well-documented responses in patients with schizophrenia (Addington, Williams, Young, & Addington, 2004). The understanding of depression and suicidality has been increasingly refined through careful study. Researchers have identified a number of factors that may cause depression such as insight into the illness, feelings of loss and inferiority about the illness as a damaging life event, hopelessness about having a viable future with the illness and mourning for losses engendered by the illness. The authors argue that grief and mourning are not just an occasional reaction to the diagnosis of schizophrenia, but are a necessary part of coming to terms with having the illness. They offer three case examples, each of which illuminates a distinct way in which psychosis and mourning may be related--psychosis as a loss of former identity, psychosis as offering meaning and transformation, and psychosis as a way of coping with the inability to mourn. In their view, recovery depends on mourning illness-related losses, developing personal meaning for the illness, and moving forward with "usable insight" and new identity (Lewis, 2004) that reflects a new understanding of one's strengths and limitations with the illness.

Updating biological bases of social behavior.

PubMed

O'Connor, Thomas G

2014-09-01

This month's collation of papers deals with social behaviors that operationalize key constructs in fields covered by the journal, including attachment theory and parenting; emotional regulation; psychopathology of several forms; general and specific cognitive abilities. Notably, many examples are offered of how these social behaviors link with biology. That is an obvious and important direction for clinical research insofar as it helps to erase a perceptual chasm and artificial duality between 'behavior' and 'biology'. But, although it must be the case that social behavior has biological connections of one sort or other, identifying reliable connections with practical application has proved to be a non-trivial challenge. In particular, the challenge seems to be in measuring social behavior meaningfully enough that it could be expected to have a biological pulse, and in measuring biological markers systematically enough that emergent-downstream effects would surface. Associations are not especially uncommon, but it has been a frustrating task in constructing a practically broad model from a bricolage of scattered and disconnected parts and findings in the literature. Several reports in this issue offer contrasts that may help move along this line of study. © 2014 Association for Child and Adolescent Mental Health.

[Parkinson's disease in literature, cinema and television].

PubMed

Collado-Vázquez, Susana; Cano-de-la-Cuerda, Roberto; Carrillo, Jesús M

2014-02-01

INTRODUCTION. Since James Parkinson published what can be considered the first treaty on the disease that bears his name in 1817, the scientific literature on this pathology has not ceased to grow. But the illness has also been represented in literature, the cinema and on television, where the symptoms, treatment and socio-familial context of the disease have often been examined very closely. AIM. To address the cases in which Parkinson's disease appears in literature, cinema and television, as well as to reflect on the image of the condition presented in those contexts. DEVELOPMENT. We reviewed some of the most important works in the literature dealing with Parkinson's disease from any period of history and many of them were found to offer very faithful portrayals of the disease. Likewise, we also reviewed major films and TV series that sometimes offer the general public a close look at the vision and the impact of the disease on patients or their relatives. CONCLUSIONS. Literature, cinema and television have helped provide a realistic view of both Parkinson's disease and the related healthcare professionals, and there are many examples that portray the actual experiences of the patients themselves, while also highlighting the importance of healthcare and socio-familial care.

The Evolution of the Penn State University Astronomy Outreach Program

NASA Astrophysics Data System (ADS)

Palma, C.; Charlton, J. C.

2008-06-01

The Penn State Dept. of Astronomy & Astrophysics has a long tradition of outreach. Faculty, students, and staff all participate as volunteers to create and deliver a variety of outreach programming to diverse audiences, including for example K-12 students, K-12 teachers, and senior citizens, in addition to open events that invite all members of the general public to attend. In the past four years, the University and the Department have provided institutional support for science outreach efforts. Many of our programs also receive financial support through NASA Education and Public outreach awards and through NSF awards to PSU Astronomy faculty. We actively collaborate with the NASA Pennsylvania Space Grant Consortium, the Penn State Center for Science and the Schools, four local school districts, and our colleagues from other science disciplines at the University. With this set of partners we are able to continue to innovate and offer new outreach programming annually. In this poster, we present an overview of the variety of outreach programs offered recently and those in the development stages. We describe how each program fits into the Department and University structure. In this way we provide a case study of a large, dynamic, university-based astronomy outreach venture.

Best Practices for Wind Energy Development in the Great Lakes Region

DOE Office of Scientific and Technical Information (OSTI.GOV)

Pebbles, Victoria; Hummer, John; Haven, Celia

2011-07-19

This report offers a menu of 18 different, yet complementary, preferred practices and policies. The best practices cover all phases of the wind energy development process - from the policies that allow for wind development, to the sustainable operation of a wind project, to the best practices for decommissioning a spent turbine - including applications for offshore wind. Each best practice describes the opportunities and challenges (pros and cons), and offers a case example that illustrates how that best practice is being utilized by a particular jurisdiction or wind project. The practices described in this publication were selected by amore » diverse group of interests from the Great Lakes Wind Collaborative that included environmental groups, industry, academia, and federal, state and local government regulators. The practices were identified through a year-long process that included a literature review, online survey and interviews with individuals from the public, private and non-profit sectors. Optimally, a suite of these best practices would be applied in an appropriate combination to fit the conditions of a particular wind project or a set of wind projects within a given locality or region.« less

A robust ordering strategy for retailers facing a free shipping option.

PubMed

Meng, Qing-chun; Wan, Xiao-le; Rong, Xiao-xia

2015-01-01

Free shipping with conditions has become one of the most effective marketing tools available. An increasing number of companies, especially e-businesses, prefer to offer free shipping with some predetermined condition, such as a minimum purchase amount by the customer. However, in practice, the demands of buyers are uncertain; they are often affected by many factors, such as the weather and season. We begin by modeling the centralized ordering problem in which the supplier offers a free shipping service and retailers face stochastic demands. As these random data are considered, only partial information such as the known mean, support, and deviation is needed. The model is then analyzed via a robust optimization method, and the two types of equivalent sets of uncertainty constraints that are obtained provide good mathematical properties with consideration of the robustness of solutions. Subsequently, a numerical example is used to compare the results achieved from a robust optimization method and the linear decision rules. Additionally, the robustness of the optimal solution is discussed, as it is affected by the minimum quantity parameters. The increasing cost-threshold relationship is divided into three periods. In addition, the case study shows that the proposed method achieves better stability as well as computational complexity.

Dental practice websites: creating a Web presence.

PubMed

Miller, Syrene A; Forrest, Jane L

2002-07-01

Web technology provides an opportunity for dentists to showcase their practice philosophy, quality of care, office setting, and staff in a creative manner. Having a Website provides a practice with innovative and cost-effective communications and marketing tools for current and potential patients who use the Internet. The main benefits of using a Website to promote one's practice are: Making office time more productive, tasks more timely, follow-up less necessary Engaging patients in an interactive and visual learning process Providing online forms and procedure examples for patients Projecting a competent and current image Tracking the usage of Web pages. Several options are available when considering the development of a Website. These options range in cost based on customization of the site and ongoing support services, such as site updates, technical assistance, and Web usage statistics. In most cases, Websites are less expensive than advertising in the phone book. Options in creating a Website include building one's own, employing a company that offers Website templates, and employing a company that offers customized sites. These development options and benefits will continue to grow as individuals access the Web and more information and sites become available.

Reflections of the social environment in chimpanzee memory: applying rational analysis beyond humans.

PubMed

Stevens, Jeffrey R; Marewski, Julian N; Schooler, Lael J; Gilby, Ian C

2016-08-01

In cognitive science, the rational analysis framework allows modelling of how physical and social environments impose information-processing demands onto cognitive systems. In humans, for example, past social contact among individuals predicts their future contact with linear and power functions. These features of the human environment constrain the optimal way to remember information and probably shape how memory records are retained and retrieved. We offer a primer on how biologists can apply rational analysis to study animal behaviour. Using chimpanzees ( Pan troglodytes ) as a case study, we modelled 19 years of observational data on their social contact patterns. Much like humans, the frequency of past encounters in chimpanzees linearly predicted future encounters, and the recency of past encounters predicted future encounters with a power function. Consistent with the rational analyses carried out for human memory, these findings suggest that chimpanzee memory performance should reflect those environmental regularities. In re-analysing existing chimpanzee memory data, we found that chimpanzee memory patterns mirrored their social contact patterns. Our findings hint that human and chimpanzee memory systems may have evolved to solve similar information-processing problems. Overall, rational analysis offers novel theoretical and methodological avenues for the comparative study of cognition.

Reflections of the social environment in chimpanzee memory: applying rational analysis beyond humans

PubMed Central

Marewski, Julian N.; Schooler, Lael J.; Gilby, Ian C.

2016-01-01

In cognitive science, the rational analysis framework allows modelling of how physical and social environments impose information-processing demands onto cognitive systems. In humans, for example, past social contact among individuals predicts their future contact with linear and power functions. These features of the human environment constrain the optimal way to remember information and probably shape how memory records are retained and retrieved. We offer a primer on how biologists can apply rational analysis to study animal behaviour. Using chimpanzees (Pan troglodytes) as a case study, we modelled 19 years of observational data on their social contact patterns. Much like humans, the frequency of past encounters in chimpanzees linearly predicted future encounters, and the recency of past encounters predicted future encounters with a power function. Consistent with the rational analyses carried out for human memory, these findings suggest that chimpanzee memory performance should reflect those environmental regularities. In re-analysing existing chimpanzee memory data, we found that chimpanzee memory patterns mirrored their social contact patterns. Our findings hint that human and chimpanzee memory systems may have evolved to solve similar information-processing problems. Overall, rational analysis offers novel theoretical and methodological avenues for the comparative study of cognition. PMID:27853606

Connecting the Space between Design and Research: Explorations in Participatory Research Supervision

ERIC Educational Resources Information Center

Caldwell, Glenda Amayo; Osborne, Lindy; Mewburn, Inger; Nottingham, Anitra

2016-01-01

In this article we offer a single case study using an action research method for gathering and analysing data offering insights valuable to both design and research supervision practice. We do not attempt to generalise from this single case, but offer it as an instance that can improve our understanding of research supervision practice. We…

Valuation of design adaptability in aerospace systems

NASA Astrophysics Data System (ADS)

Fernandez Martin, Ismael

As more information is brought into early stages of the design, more pressure is put on engineers to produce a reliable, high quality, and financially sustainable product. Unfortunately, requirements established at the beginning of a new project by customers, and the environment that surrounds them, continue to change in some unpredictable ways. The risk of designing a system that may become obsolete during early stages of production is currently tackled by the use of robust design simulation, a method that allows to simultaneously explore a plethora of design alternatives and requirements with the intention of accounting for uncertain factors in the future. Whereas this design technique has proven to be quite an improvement in design methods, under certain conditions, it fails to account for the change of uncertainty over time and the intrinsic value embedded in the system when certain design features are activated. This thesis introduces the concepts of adaptability and real options to manage risk foreseen in the face of uncertainty at early design stages. The method described herein allows decision-makers to foresee the financial impact of their decisions at the design level, as well as the final exposure to risk. In this thesis, cash flow models, traditionally used to obtain the forecast of a project's value over the years, were replaced with surrogate models that are capable of showing fluctuations on value every few days. This allowed a better implementation of real options valuation, optimization, and strategy selection. Through the option analysis model, an optimization exercise allows the user to obtain the best implementation strategy in the face of uncertainty as well as the overall value of the design feature. Here implementation strategy refers to the decision to include a new design feature in the system, after the design has been finalized, but before the end of its production life. The ability to do this in a cost efficient manner after the system design is under production is referred to as adaptability. This thesis contains two relevant examples regarding the decision of introducing new technologies. First, the case study of Southwest Airlines, and the decision it took to retrofit blended winglets technology in its already delivered Boeing 737-700, is introduced as a validation exercise and for calibration purposes. Such case also demonstrates that the method is applicable to a real life example with simple technologies. The second example analyzes the decision of introducing new technologies into the design of the new jet engine to power the next generation of narrow body aircraft. The development of such aircraft, set to replace the Boeing 737 and Airbus 320 models, is currently at conceptual levels. In this case, the manufacturer evaluates whether technologies should be included in the design, left out, or offered as an option to retrofit in the future. This case demonstrates the benefits of each of these actions and the monetary value of offering retrofitting options as upgrades to the airlines when the value of the technology fluctuates considerably between profitable and not profitable. The purpose of this case is to demonstrate the applicability of the method to the preliminary design phases of complex systems while accounting for uncertainty of external factors over time.

Hepatitis A Cases Among Food Handlers: A Local Health Department Response-New York City, 2013.

PubMed

Ridpath, Alison; Reddy, Vasudha; Layton, Marcelle; Misener, Mark; Scaccia, Allison; Starr, David; Stavinsky, Faina; Varma, Jay K; Waechter, HaeNa; Zucker, Jane R; Balter, Sharon

During 2013, the New York City Department of Health and Mental Hygiene (DOHMH) received reports of 6 hepatitis A cases among food handlers. We describe our decision-making process for public notification, type of postexposure prophylaxis (PEP) offered, and lessons learned. For 3 cases, public notification was issued and DOHMH offered only hepatitis A vaccine as PEP. Subsequent outbreaks resulted from 1 case for which no public notification was issued or PEP offered, and 1 for which public notification was issued and PEP was offered too late. DOHMH continues to use environmental assessments to guide public notification decisions and offer only hepatitis A vaccine as PEP after public notification but recognizes the need to evaluate each situation individually. The PEP strategy employed by DOHMH should be considered because hepatitis A vaccine is immunogenic in all age groups, can be obtained by local jurisdictions more quickly, and is logistically easier to administer in mass clinics than immunoglobulin.

U-series disequilibria in crystals: ages as tracers

NASA Astrophysics Data System (ADS)

Cooper, K. M.

2005-12-01

U-series disequilibria offer a unique perspective on the fates of crystals within magmatic systems. In addition to delimiting the timescales of magmatic processes, crystal ages can be used as a tracer of different crystal populations even in the case where only subtle differences exist between major- and trace-element chemistries of populations. For example, 226Ra-230Th ages of crystals in Mt St Helens lavas erupted since 2 ka are in some cases several kyr older than eruption ages which, when combined with significant Ra-Th disequilibria in the whole-rocks, suggests protracted crystal storage and entrainment in subsequent batches of magma passing through the reservoir. More broadly, in many cases 230Th-238U and 226Ra-230Th ages measured in the same crystals are discordant. This pattern likely indicates progressive and/or episodic crystal growth where the Th-U ages more closely represent average crystallization ages while Ra-Th ages are weighted toward recent growth, suggesting in turn that some significant fraction of the mass of crystals represent xenocrysts or "antecrysts" recycled from earlier generations of magmas within the same system. Conversely, in cases where ages of different parent-daughter pairs are concordant, mineral separates must be dominated by crystal growth within a relatively narrow time interval relative to the half-life of the shortest-lived daughter isotope. The duration of the crystal record within a given magma can be complicated by crystal recycling and obscured by average ages derived from measurement of bulk mineral separates. One way to extract more information about the proportion and ages of older and younger parts of the crystal population(s) is to analyze different size fractions within the same sample; for example, analyses of different sizes of plagioclase from the ongoing eruption at Mt St Helens are in progress. U-series ages and other crystal-scale geochemical information can also be a powerful combination. For example, preservation of major- or trace-element disequilibrium between zones within crystals limits the duration of crystal residence at high temperature; when combined with absolute age information from U-series disequilibria, these data can provide clues about the thermal conditions of crystal storage and thus whether such storage is likely to have occurred in a mostly-liquid or mostly-crystalline part of the magma system.

Integrating art into science education: a survey of science teachers' practices

NASA Astrophysics Data System (ADS)

Turkka, Jaakko; Haatainen, Outi; Aksela, Maija

2017-07-01

Numerous case studies suggest that integrating art and science education could engage students with creative projects and encourage students to express science in multitude of ways. However, little is known about art integration practices in everyday science teaching. With a qualitative e-survey, this study explores the art integration of science teachers (n = 66). A pedagogical model for science teachers' art integration emerged from a qualitative content analysis conducted on examples of art integration. In the model, art integration is characterised as integration through content and activities. Whilst the links in the content were facilitated either directly between concepts and ideas or indirectly through themes or artefacts, the integration through activity often connected an activity in one domain and a concept, idea or artefact in the other domain with the exception of some activities that could belong to both domains. Moreover, the examples of art integration in everyday classroom did not include expression of emotions often associated with art. In addition, quantitative part of the survey confirmed that integration is infrequent in all mapped areas. The findings of this study have implications for science teacher education that should offer opportunities for more consistent art integration.

Consent to medical research of vulnerable subjects from the French point of view: the example of consent in research in the case of Alzheimer disease.

PubMed

Duguet, Anne-Marie; Boyer-Beviere, Bénédicte

2011-12-01

The consent to research is the expression of autonomy. Some groups are vulnerable and cannot give free consent because their conditions limit their decision making or because they are unable to consent themselves (minor, incompetent adults). International standards and recommendations for medical research protect vulnerable subjects (article 17 of the Helsinki declaration, guidelines 9 and 13 of the CIOMS, article 17 of the Oviedo Convention). French Law protects mostly three categories of vulnerable people: minors, adults with a legal representative, and the people living in sanitary and social establishments. Specific protection is given as well to pregnant women, detainees and persons with psychiatric disorders in involuntary commitment. From the example of research with Alzheimer patients the authors show the original provisions of French legislation to involve in medical research incompetent patients with or without legal protection. Clinical research on Alzheimer's disease poses challenges as never before to research ethics. In fact, the development of the disease progressively reduces the patient's ability to make choices: the latter is no longer capable, but is not totally incapacitated. Several solutions are offered for a "proxy" consent or authorisation.

TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data

PubMed Central

Colaprico, Antonio; Silva, Tiago C.; Olsen, Catharina; Garofano, Luciano; Cava, Claudia; Garolini, Davide; Sabedot, Thais S.; Malta, Tathiane M.; Pagnotta, Stefano M.; Castiglioni, Isabella; Ceccarelli, Michele; Bontempi, Gianluca; Noushmehr, Houtan

2016-01-01

The Cancer Genome Atlas (TCGA) research network has made public a large collection of clinical and molecular phenotypes of more than 10 000 tumor patients across 33 different tumor types. Using this cohort, TCGA has published over 20 marker papers detailing the genomic and epigenomic alterations associated with these tumor types. Although many important discoveries have been made by TCGA's research network, opportunities still exist to implement novel methods, thereby elucidating new biological pathways and diagnostic markers. However, mining the TCGA data presents several bioinformatics challenges, such as data retrieval and integration with clinical data and other molecular data types (e.g. RNA and DNA methylation). We developed an R/Bioconductor package called TCGAbiolinks to address these challenges and offer bioinformatics solutions by using a guided workflow to allow users to query, download and perform integrative analyses of TCGA data. We combined methods from computer science and statistics into the pipeline and incorporated methodologies developed in previous TCGA marker studies and in our own group. Using four different TCGA tumor types (Kidney, Brain, Breast and Colon) as examples, we provide case studies to illustrate examples of reproducibility, integrative analysis and utilization of different Bioconductor packages to advance and accelerate novel discoveries. PMID:26704973

Ritual uses of palms in traditional medicine in sub-Saharan Africa: a review

PubMed Central

2014-01-01

Palms (Arecaceae) are prominent elements in African traditional medicines. It is, however, a challenge to find detailed information on the ritual use of palms, which are an inextricable part of African medicinal and spiritual systems. This work reviews ritual uses of palms within African ethnomedicine. We studied over 200 publications on uses of African palms and found information about ritual uses in 26 of them. At least 12 palm species in sub-Saharan Africa are involved in various ritual practices: Borassus aethiopum, Cocos nucifera, Dypsis canaliculata, D. fibrosa, D. pinnatifrons, Elaeis guineensis, Hyphaene coriacea, H. petersiana, Phoenix reclinata, Raphia farinifera, R. hookeri, and R. vinifera. In some rituals, palms play a central role as sacred objects, for example the seeds accompany oracles and palm leaves are used in offerings. In other cases, palms are added as a support to other powerful ingredients, for example palm oil used as a medium to blend and make coherent the healing mixture. A better understanding of the cultural context of medicinal use of palms is needed in order to obtain a more accurate and complete insight into palm-based traditional medicines. PMID:25056559

An overview of STRUCTURE: applications, parameter settings, and supporting software

PubMed Central

Porras-Hurtado, Liliana; Ruiz, Yarimar; Santos, Carla; Phillips, Christopher; Carracedo, Ángel; Lareu, Maria V.

2013-01-01

Objectives: We present an up-to-date review of STRUCTURE software: one of the most widely used population analysis tools that allows researchers to assess patterns of genetic structure in a set of samples. STRUCTURE can identify subsets of the whole sample by detecting allele frequency differences within the data and can assign individuals to those sub-populations based on analysis of likelihoods. The review covers STRUCTURE's most commonly used ancestry and frequency models, plus an overview of the main applications of the software in human genetics including case-control association studies (CCAS), population genetics, and forensic analysis. The review is accompanied by supplementary material providing a step-by-step guide to running STRUCTURE. Methods: With reference to a worked example, we explore the effects of changing the principal analysis parameters on STRUCTURE results when analyzing a uniform set of human genetic data. Use of the supporting software: CLUMPP and distruct is detailed and we provide an overview and worked example of STRAT software, applicable to CCAS. Conclusion: The guide offers a simplified view of how STRUCTURE, CLUMPP, distruct, and STRAT can be applied to provide researchers with an informed choice of parameter settings and supporting software when analyzing their own genetic data. PMID:23755071

Monitoring and Modeling: The Future of Volcanic Eruption Forecasting

NASA Astrophysics Data System (ADS)

Poland, M. P.; Pritchard, M. E.; Anderson, K. R.; Furtney, M.; Carn, S. A.

2016-12-01

Eruption forecasting typically uses monitoring data from geology, gas geochemistry, geodesy, and seismology, to assess the likelihood of future eruptive activity. Occasionally, months to years of warning are possible from specific indicators (e.g., deep LP earthquakes, elevated CO2 emissions, and aseismic deformation) or a buildup in one or more monitoring parameters. More often, observable changes in unrest occur immediately before eruption, as magma is rising toward the surface. In some cases, little or no detectable unrest precedes eruptive activity. Eruption forecasts are usually based on the experience of volcanologists studying the activity, but two developing fields offer a potential leap beyond this practice. First, remote sensing data, which can track thermal, gas, and ash emissions, as well as surface deformation, are increasingly available, allowing statistically significant research into the characteristics of unrest. For example, analysis of hundreds of volcanoes indicates that deformation is a more common pre-eruptive phenomenon than thermal anomalies, and that most episodes of satellite-detected unrest are not immediately followed by eruption. Such robust datasets inform the second development—probabilistic models of eruption potential, especially those that are based on physical-chemical models of the dynamics of magma accumulation and ascent. Both developments are essential for refining forecasts and reducing false positives. For example, many caldera systems have not erupted but are characterized by unrest that, in another context, would elicit strong concern from volcanologists. More observations of this behavior and better understanding of the underlying physics of unrest will improve forecasts of such activity. While still many years from implementation as a forecasting tool, probabilistic physio-chemical models incorporating satellite data offer a complement to expert assessments that, together, can form a powerful forecasting approach.

Up in Smoke.

ERIC Educational Resources Information Center

Black, Susan

2002-01-01

Reviews research on adolescent smoking and nicotine addiction. Finds, for example, that smoking is linked to depression. Describes five stages of nicotine addiction. Offers tips for prevention. (Contains 12 references.) (PKP)

Designs for Change: Libraries and Productive Aging. Report on the National Library Leaders Forum (Washington, DC, September 26-27, 2005)

ERIC Educational Resources Information Center

Zeisel, William

2006-01-01

As the first of the baby boomers turn 60, public libraries are preparing to offer creative alternatives to retirement to a generation notorious for their idealism and activism. This report from the Americans for Libraries Council (ALC) and the Institute of Museum and Library Services (IMLS) offers guidelines, demographics, and examples of model…

How to Teach Yourself Physical Skills: An Audio Tape for College Students with Some Introductory Comments and a Detailed Outline.

ERIC Educational Resources Information Center

Hodges, Daniel L.

This guide provides a detailed summary of the information, techniques, and examples offered in an audiotape developed to help students teach themselves physical skills. After section I introduces the topic and the objectives of the tape, section II provides concrete examples of adults learning motor skills. Section III presents and discusses nine…

An Inexpensive Toroidal Solenoid for an Investigative Student Lab

NASA Astrophysics Data System (ADS)

Ferstl, Andrew; Broberg, John

2008-09-01

Magnetism and Ampère's law is a common subject in most calculus-based introductory physics courses. Many textbooks offer examples to calculate the magnetic field produced by a symmetric current by using Ampère's law. These examples include the solenoid and the toroidal solenoid (sometimes called a torus; see Fig. 1), which are used in many applications, including the study of plasmas.

Navigating Institutions and Institutional Leadership to Address Sexual Violence

ERIC Educational Resources Information Center

Sisneros, Kathy; Rivera, Monica

2018-01-01

Using an institutional example, this chapter offers strategies to effectively navigate institutional culture, processes, and structures to engage the entire campus community in addressing sexual violence.

Survey highlights the need to expand offerings of introductory pharmacy practice experiences in psychiatry and neurology: Benefits and example experiences.

PubMed

Bostwick, Jolene R; Leung, Gillian P; Smith, Tawny L; Ahmed, Uzma; Bainbridge, Jacquelyn L; Peyronnet, Jean-Xavier

2018-01-01

Introductory pharmacy practice experiences (IPPEs) are 1 requirement schools and colleges of pharmacy must fulfill to meet accreditation standards. The purpose of this manuscript is to report existing IPPEs in psychiatry and neurology across the United States. Two separate electronic surveys were administered to individual College of Psychiatric and Neurologic Pharmacists members with board certification in psychiatric pharmacy with an academic affiliation and academic institutions in the 2014-15 academic year to assess the neuropsychiatric curriculum in pharmacy programs. Results focusing on IPPEs were summarized using descriptive statistics. Academic institutional data reveal only 37.3% offered IPPEs in psychiatry, and 6.7% offered neurology. The number of available IPPEs is low even if a program offered an available rotation. The majority of College of Psychiatric and Neurologic Pharmacists member respondents (69.9%) did not offer IPPEs in psychiatry in the 2014-15 academic year, and none offered an IPPE in neurology. More than half of individual respondents feel their institution should increase IPPEs in psychiatry and neurology in order to enhance their curriculum. To expand IPPE availability, pharmacy programs should increase early exposure of pharmacy students to patients with psychiatric and neurologic conditions. Longitudinal experiences may allow students to engage in hands-on experiences, which may impact future career aspirations and reduce stigma. Current example IPPEs at the authors' institutions are included to stimulate discussion and action among readers on how IPPEs in these practice areas may be developed. Implementation of IPPEs in psychiatry and neurology is needed for students to gain experience working with these patients.

Shifting the focus: outcomes of care for older people.

PubMed

Heath, Hazel; Phair, Lynne

2009-06-01

Internationally there is commitment to work towards eradicating the abuse of older people and to develop services that promote their equality, dignity and human rights. The emphasis on service users is gradually increasing and, along with this, the focus within health and social care policy, service provision and professional practice is shifting. In UK health and social care policy the emphasis on service structure and provision is being replaced by a focus on outcomes for service users, including outcomes which patients themselves evaluate. The focus of UK Adult Protection services is also shifting from intervention to prevention through developing greater understanding of the factors which contribute to abuse, changing attitudes towards entrenched poor care, identifying preventative services and safeguarding vulnerable adults. Nursing literature is also beginning to acknowledge the evolution of an outcomes focus. This paper discusses the shifting emphasis in UK health and social care in the safeguarding of vulnerable people and in nursing practice. It offers an overview of literature on outcomes. The paper then describes a research study which sought to identify outcomes of care for older people living in UK care homes. The outcomes framework developed through the research is offered, along with a discussion of the advantages of an outcome-focused approach to care and some of the remaining challenges. A case example is offered to illustrate an outcomes-focused approach. Finally, the paper draws conclusions on how shifting the focus of care delivery from traditional problem-orientated approaches and ritualized practice towards the outcomes of care that individual older people choose and evaluate for themselves offers potential towards eradicating abuse and neglect in formal care settings. © 2009 Blackwell Publishing Ltd.

MPH education for the 21st century: motivation, rationale, and key principles for the new Columbia public health curriculum.

PubMed

Fried, Linda P; Begg, Melissa D; Bayer, Ronald; Galea, Sandro

2014-01-01

Public health is at a watershed moment. The world's health needs are changing, and complex problems require interdisciplinary approaches and systems-based solutions. Our longer lives and changing environments necessitate life-course and structural approaches to prevention. This argues strongly for public health graduate education that adequately prepares trainees to tackle emerging challenges and to lead now and in the future. Nearly a century of scholarship and scientific advances may offer a blueprint for training the next generation of public health leaders. We articulate a case for change; discuss some of the foundational principles that should guide public health education; and discuss what such a change might look like building on prior scholarship, on the examples set by other disciplines, and on our own experience.

MPH Education for the 21st Century: Motivation, Rationale, and Key Principles for the New Columbia Public Health Curriculum

PubMed Central

Fried, Linda P.; Begg, Melissa D.; Bayer, Ronald

2014-01-01

Public health is at a watershed moment. The world’s health needs are changing, and complex problems require interdisciplinary approaches and systems-based solutions. Our longer lives and changing environments necessitate life-course and structural approaches to prevention. This argues strongly for public health graduate education that adequately prepares trainees to tackle emerging challenges and to lead now and in the future. Nearly a century of scholarship and scientific advances may offer a blueprint for training the next generation of public health leaders. We articulate a case for change; discuss some of the foundational principles that should guide public health education; and discuss what such a change might look like building on prior scholarship, on the examples set by other disciplines, and on our own experience. PMID:24228646

Organization and management of space grant programs

NASA Technical Reports Server (NTRS)

Sheppard, Sallie; Nichols, Steve

1990-01-01

The 21 Space Grant Programs represent a broad range of organizational structures which operate programs ranging in size from single university organizations to organizations including up to 41 members involving a composite of industrial organizations such as state agencies, and universities. Some of the space grant awards were made to organizations already in existence with on-going programs while other awards were made to consortia newly formed for the purpose of applying to the Space Grant Program. The workshop on organization and management of Space Grant Programs provided an opportunity for directors and program representatives to discuss and compare the relative advantages and disadvantages of the various models being used. This paper offers examples of the diversity of organizations, summarizes the common concerns to be met by each organizational model, and provides a case study of the Texas Space Grant Consortium organization.

Dynamics of Receptor-Mediated Nanoparticle Internalization into Endothelial Cells

PubMed Central

Gonzalez-Rodriguez, David; Barakat, Abdul I.

2015-01-01

Nanoparticles offer a promising medical tool for targeted drug delivery, for example to treat inflamed endothelial cells during the development of atherosclerosis. To inform the design of such therapeutic strategies, we develop a computational model of nanoparticle internalization into endothelial cells, where internalization is driven by receptor-ligand binding and limited by the deformation of the cell membrane and cytoplasm. We specifically consider the case of nanoparticles targeted against ICAM-1 receptors, of relevance for treating atherosclerosis. The model computes the kinetics of the internalization process, the dynamics of binding, and the distribution of stresses exerted between the nanoparticle and the cell membrane. The model predicts the existence of an optimal nanoparticle size for fastest internalization, consistent with experimental observations, as well as the role of bond characteristics, local cell mechanical properties, and external forces in the nanoparticle internalization process. PMID:25901833

Pelvic and lower extremity injuries in Homer's Iliad: a review of the literature.

PubMed

Galanakos, Spyridon P; Bot, Arjan G J; Macheras, George A

2015-01-01

The Iliad, composed approximately in the middle of the eighth century bc, constitutes the leading and oldest known example of heroic epic. The Homeric epic presents the conflicts that took place during the last year of the 10-year lasting Trojan War, offering a realistic description of battle wounds. We studied the text of The Iliad in ancient Greek and in the translations in modern Greek and English and searched for all recorded injuries to the pelvis and lower extremities. A total of 16 traumatic injuries of pelvis and lower extremities were described, including 7 fatal wounds, while in 9 cases, the outcome was unknown.The Iliad remains the oldest record of Greek medicine and a unique source of surgical history. To study the vividly reported events is a great experience, particularly for a surgeon.

Efficient hydrogen isotopologues separation through a tunable potential barrier: The case of a C2N membrane.

PubMed

Qu, Yuanyuan; Li, Feng; Zhao, Mingwen

2017-05-03

Isotopes separation through quantum sieving effect of membranes is quite promising for industrial applications. For the light hydrogen isotopologues (eg. H 2 , D 2 ), the confinement of potential wells in porous membranes to isotopologues was commonly regarded to be crucial for highly efficient separation ability. Here, we demonstrate from first-principles that a potential barrier is also favorable for efficient hydrogen isotopologues separation. Taking an already-synthesized two-dimensional carbon nitride (C 2 N-h2D) as an example, we predict that the competition between quantum tunneling and zero-point-energy (ZPE) effects regulated by the tensile strain leads to high selectivity and permeance. Both kinetic quantum sieving and equilibrium quantum sieving effects are considered. The quantum effects revealed in this work offer a prospective strategy for highly efficient hydrogen isotopologues separation.

Intranasal delivery: physicochemical and therapeutic aspects.

PubMed

Costantino, Henry R; Illum, Lisbeth; Brandt, Gordon; Johnson, Paul H; Quay, Steven C

2007-06-07

Interest in intranasal (IN) administration as a non-invasive route for drug delivery continues to grow rapidly. The nasal mucosa offers numerous benefits as a target issue for drug delivery, such as a large surface area for delivery, rapid drug onset, potential for central nervous system delivery, and no first-pass metabolism. A wide variety of therapeutic compounds can be delivered IN, including relatively large molecules such as peptides and proteins, particularly in the presence of permeation enhancers. The current review provides an in-depth discussion of therapeutic aspects of IN delivery including consideration of the intended indication, regimen, and patient population, as well as physicochemical properties of the drug itself. Case examples are provided to illustrate the utility of IN dosing. It is anticipated that the present review will prove useful for formulation scientists considering IN delivery as a delivery route.

Cross-Training: The Tactical View.

ERIC Educational Resources Information Center

Kaeter, Margaret

1993-01-01

Discusses the advantages of and problems associated with cross-training. Looks at the issue of remuneration and offers examples of how two companies that cross-train presently pay their employees. (JOW)

Water supply management using an extended group fuzzy decision-making method: a case study in north-eastern Iran

NASA Astrophysics Data System (ADS)

Minatour, Yasser; Bonakdari, Hossein; Zarghami, Mahdi; Bakhshi, Maryam Ali

2015-09-01

The purpose of this study was to develop a group fuzzy multi-criteria decision-making method to be applied in rating problems associated with water resources management. Thus, here Chen's group fuzzy TOPSIS method extended by a difference technique to handle uncertainties of applying a group decision making. Then, the extended group fuzzy TOPSIS method combined with a consistency check. In the presented method, initially linguistic judgments are being surveyed via a consistency checking process, and afterward these judgments are being used in the extended Chen's fuzzy TOPSIS method. Here, each expert's opinion is turned to accurate mathematical numbers and, then, to apply uncertainties, the opinions of group are turned to fuzzy numbers using three mathematical operators. The proposed method is applied to select the optimal strategy for the rural water supply of Nohoor village in north-eastern Iran, as a case study and illustrated example. Sensitivity analyses test over results and comparing results with project reality showed that proposed method offered good results for water resources projects.

Designing and assessing a sustainable networked delivery (SND) system: hybrid business-to-consumer book delivery case study.

PubMed

Kim, Junbeum; Xu, Ming; Kahhat, Ramzy; Allenby, Braden; Williams, Eric

2009-01-01

We attempted to design and assess an example of a sustainable networked delivery (SND) system: a hybrid business-to-consumer book delivery system. This system is intended to reduce costs, achieve significant reductions in energy consumption, and reduce environmental emissions of critical local pollutants and greenhouse gases. The energy consumption and concomitant emissions of this delivery system compared with existing alternative delivery systems were estimated. We found that regarding energy consumption, an emerging hybrid delivery system which is a sustainable networked delivery system (SND) would consume 47 and 7 times less than the traditional networked delivery system (TND) and e-commerce networked delivery system (END). Regarding concomitant emissions, in the case of CO2, the SND system produced 32 and 7 times fewer emissions than the TND and END systems. Also the SND system offer meaningful economic benefit such as the costs of delivery and packaging, to the online retailer, grocery, and consumer. Our research results show that the SND system has a lot of possibilities to save local transportation energy consumption and delivery costs, and reduce environmental emissions in delivery system.

Neuroethics: A New Way of Doing Ethics

PubMed Central

Levy, Neil

2011-01-01

The aim of this article is to argue, by example, for neuroethics as a new way of doing ethics. Rather than simply giving us a new subject matter—the ethical issues arising from neuroscience—to attend to, neuroethics offers us the opportunity to refine the tools we use. Ethicists often need to appeal to the intuitions provoked by consideration of cases to evaluate the permissibility of types of actions; data from the sciences of the mind give us reason to believe that some of these intuitions are less reliable than others. I focus on the doctrine of double effect to illustrate my case, arguing that experimental results suggest that appeal to it might be question-begging. The doctrine of double effect is supposed to show that there is a moral difference between effects that are brought about intentionally and those that are merely foreseen; I argue that the data suggest that we regard some effects as merely foreseen only because we regard bringing them about as permissible. Appeal to the doctrine of double effect therefore cannot establish that there are such moral differences. PMID:22318976

Point-of-care testing in the early diagnosis of acute pesticide intoxication: The example of paraquat.

PubMed

Wei, Ting-Yen; Yen, Tzung-Hai; Cheng, Chao-Min

2018-01-01

Acute pesticide intoxication is a common method of suicide globally. This article reviews current diagnostic methods and makes suggestions for future development. In the case of paraquat intoxication, it is characterized by multi-organ failure, causing substantial mortality and morbidity. Early diagnosis may save the life of a paraquat intoxication patient. Conventional paraquat intoxication diagnostic methods, such as symptom review and urine sodium dithionite assay, are time-consuming and impractical in resource-scarce areas where most intoxication cases occur. Several experimental and clinical studies have shown the potential of portable Surface Enhanced Raman Scattering (SERS), paper-based devices, and machine learning for paraquat intoxication diagnosis. Portable SERS and new SERS substrates maintain the sensitivity of SERS while being less costly and more convenient than conventional SERS. Paper-based devices provide the advantages of price and portability. Machine learning algorithms can be implemented as a mobile phone application and facilitate diagnosis in resource-limited areas. Although these methods have not yet met all features of an ideal diagnostic method, the combination and development of these methods offer much promise.

Domino: Extracting, Comparing, and Manipulating Subsets across Multiple Tabular Datasets

PubMed Central

Gratzl, Samuel; Gehlenborg, Nils; Lex, Alexander; Pfister, Hanspeter; Streit, Marc

2016-01-01

Answering questions about complex issues often requires analysts to take into account information contained in multiple interconnected datasets. A common strategy in analyzing and visualizing large and heterogeneous data is dividing it into meaningful subsets. Interesting subsets can then be selected and the associated data and the relationships between the subsets visualized. However, neither the extraction and manipulation nor the comparison of subsets is well supported by state-of-the-art techniques. In this paper we present Domino, a novel multiform visualization technique for effectively representing subsets and the relationships between them. By providing comprehensive tools to arrange, combine, and extract subsets, Domino allows users to create both common visualization techniques and advanced visualizations tailored to specific use cases. In addition to the novel technique, we present an implementation that enables analysts to manage the wide range of options that our approach offers. Innovative interactive features such as placeholders and live previews support rapid creation of complex analysis setups. We introduce the technique and the implementation using a simple example and demonstrate scalability and effectiveness in a use case from the field of cancer genomics. PMID:26356916

Narrative methods in quality improvement research

PubMed Central

Greenhalgh, T; Russell, J; Swinglehurst, D

2005-01-01



 This paper reviews and critiques the different approaches to the use of narrative in quality improvement research. The defining characteristics of narrative are chronology (unfolding over time); emplotment (the literary juxtaposing of actions and events in an implicitly causal sequence); trouble (that is, harm or the risk of harm); and embeddedness (the personal story nests within a particular social, historical and organisational context). Stories are about purposeful action unfolding in the face of trouble and, as such, have much to offer quality improvement researchers. But the quality improvement report (a story about efforts to implement change), which is common, must be distinguished carefully from narrative based quality improvement research (focused systematic enquiry that uses narrative methods to generate new knowledge), which is currently none. We distinguish four approaches to the use of narrative in quality improvement research—narrative interview; naturalistic story gathering; organisational case study; and collective sense-making—and offer a rationale, describe how data can be collected and analysed, and discuss the strengths and limitations of each using examples from the quality improvement literature. Narrative research raises epistemological questions about the nature of narrative truth (characterised by sense-making and emotional impact rather than scientific objectivity), which has implications for how rigour should be defined (and how it might be achieved) in this type of research. We offer some provisional guidance for distinguishing high quality narrative research in a quality improvement setting from other forms of narrative account such as report, anecdote, and journalism. PMID:16326792

Must the show go on? The case for Theatre for Development.

PubMed

Prentki, T

1998-11-01

This article discusses the reasons for use and nonuse of folk theater for communicating development messages. Theater for Development (TFD) is a tool used by development agencies for improving the quality of life among vulnerable populations. TFD uses fiction and the "safe space" of performance to comment on reality and offer alternatives. The medium offers the opportunity to explore roles that would normally be denied in real life and to explore a community's developmental aspirations. Most TFD draws on talent from the dramatic arts that is unfamiliar with development perspectives. TFD is finally being recognized as important for cultural expression suitable for self-development. Communication is the single most important aspect in the process of development. The constraints to TFD are lack of inclusion within development policy, the lack of development artists, and most importantly, time. Groups with a history of silence, oppression, and marginalization need facilitators. The Freirean model is a consciousness raising one. Participatory theater is centuries old. The most vigorous, sustained TFD theaters are in places with deprivation, poverty, disease, and hunger. These situations are well suited to TFD as a critical intervention for change. An example from the Nigerian Popular Theater Alliance is used to illustrate consciousness raising about government provision of services. TFD allows communities to draw agendas of their own. India has a substantial tradition of Social Action Groups and street theater. TFD can reverse power relations, is not dependent on literacy, and offers an entertaining way of spreading information.

Development of Palliative Care in China: A Tale of Three Cities

PubMed Central

Yin, Zhenyu; Li, Jinxiang; Ma, Ke; Ning, Xiaohong; Chen, Huiping; Fu, Haiyan; Zhang, Haibo; Wang, Chun; Bruera, Eduardo

2017-01-01

Abstract Background. China is the most populous country in the world, but access to palliative care is extremely limited. A better understanding of the development of palliative care programs in China and how they overcome the barriers to provide services would inform how we can further integrate palliative care into oncology practices in China. Here, we describe the program development and infrastructure of the palliative care programs at three Chinese institutions, using these as examples to discuss strategies to accelerate palliative care access for cancer patients in China. Methods. Case study of three palliative care programs in Chengdu, Kunming, and Beijing. Results. The three examples of palliative care delivery in China ranged from a comprehensive program that includes all major branches of palliative care in Chengdu, a program that is predominantly inpatient‐based in Kunming, and a smaller program at an earlier stage of development in Beijing. Despite the numerous challenges related to the limited training opportunities, stigma on death and dying, and lack of resources and policies to support clinical practice, these programs were able to overcome many barriers to offer palliative care services to patients with advanced diseases and to advance this discipline in China through visionary leadership, collaboration with other countries to acquire palliative care expertise, committed staff members, and persistence. Conclusion. Palliative care is limited in China, although a few comprehensive programs exist. Our findings may inform palliative care program development in other Chinese hospitals. Implications for Practice. With a population of 1.3 billion, China is the most populous country in the world, and cancer is the leading cause of death. However, only 0.7% of hospitals offer palliative care services, which significantly limits palliative care access for Chinese cancer patients. Here, we describe the program development and infrastructure of three palliative care programs in China, using these as examples to discuss how they were able to overcome various barriers to implement palliative care. Lessons from these programs may help to accelerate the progress of palliative cancer care in China. PMID:28739870

Isolating the Effects of Training Using Simple Regression Analysis: An Example of the Procedure.

ERIC Educational Resources Information Center

Waugh, C. Keith

This paper provides a case example of simple regression analysis, a forecasting procedure used to isolate the effects of training from an identified extraneous variable. This case example focuses on results of a three-day sales training program to improve bank loan officers' knowledge, skill-level, and attitude regarding solicitation and sale of…

5 CFR 2635.203 - Definitions.

Code of Federal Regulations, 2013 CFR

2013-01-01

... paid for by the Government or secured by the Government under Government contract; Note: Some airlines... offered because of their official positions. Example 2: Employees at a regional office of the Department...

5 CFR 2635.203 - Definitions.

Code of Federal Regulations, 2012 CFR

2012-01-01

... paid for by the Government or secured by the Government under Government contract; Note: Some airlines... offered because of their official positions. Example 2: Employees at a regional office of the Department...

5 CFR 2635.203 - Definitions.

Code of Federal Regulations, 2014 CFR

2014-01-01

... paid for by the Government or secured by the Government under Government contract; Note: Some airlines... offered because of their official positions. Example 2: Employees at a regional office of the Department...

Seeing Glass Contractors Clearly.

ERIC Educational Resources Information Center

Deliberato, Jerry

2003-01-01

Offers seven tips for finding and working with an effective glass contractor. For example, schools should consider the company's reputation and longevity of service, and whether it has in-house engineering capabilities. (EV)

Data Use and Inquiry in Research-Practice Partnerships: Four Case Examples

ERIC Educational Resources Information Center

Biag, Manuelito; Gerstein, Amy; Fehrer, Kendra; Sanchez, Monika; Sipes, Laurel

2016-01-01

The four case examples presented in this brief are drawn from the Gardner Center's substantial experience conducting rigorous research in research-practice partnerships. The first case describes a partnership approach that enhances a school district's capacity to use integrated longitudinal data to tackle persistent problems of practice and…

Nuclear reactor melt arrest and coolability device

DOEpatents

Theofanous, Theo G.; Dinh, Nam Truc; Wachowiak, Richard M.

2016-06-14

Example embodiments provide a Basemat-Internal Melt Arrest and Coolability device (BiMAC) that offers improved spatial and mechanical characteristics for use in damage prevention and risk mitigation in accident scenarios. Example embodiments may include a BiMAC having an inclination of less than 10-degrees from the basemat floor and/or coolant channels of less than 4 inches in diameter, while maintaining minimum safety margins required by the Nuclear Regulatory Commission.

Integrating Asian Film into Film Studies and Film Production Courses Using Examples from Yasujiro Ozu (Japan) and Zhang Yimou (China). Asian Studies Module, 1997.

ERIC Educational Resources Information Center

Carson, Diane

This curriculum module offers concrete and specific examples for instructors who wish to integrate the films of Yasujiro Ozu of Japan and Zhang Yimou from China into film studies courses. Through this module, students should learn to compare and contrast conventional screen space, color, and editing to alternative forms. By becoming more familiar…

Polio Pictures

MedlinePlus

... dimensional representation of poliovirus. A few examples from public health professionals Child in Nigeria with a leg partly ... for these sites, which offer more images/photos. Public Health Image Library (PHIL) Immunization Action Coalition Polio Eradication ...

7 CFR 1410.31 - Acceptability of offers.

Code of Federal Regulations, 2010 CFR

2010-01-01

... include, but are not limited to: (1) Soil erosion; (2) Water quality (both surface and ground water); (3... use beyond the contract period, considering, for example, tree planting, permanent wildlife habitat...

7 CFR 1410.31 - Acceptability of offers.

Code of Federal Regulations, 2011 CFR

2011-01-01

... include, but are not limited to: (1) Soil erosion; (2) Water quality (both surface and ground water); (3... use beyond the contract period, considering, for example, tree planting, permanent wildlife habitat...

Adolescent Homosexual Behavior and the Health Educator.

ERIC Educational Resources Information Center

Chng, Chwee Lye

1980-01-01

Approaches for teaching about homosexuality as part of the school health curriculum are offered. Suggestions include discussion of popular values and stereotypes, teaching by example, and teaching through role playing. (JMF)

Biology Today: Parasites and Human Ecology.

ERIC Educational Resources Information Center

Flannery, Maura C.

1984-01-01

Offers various reasons why the study of parasites and the diseases they cause should be incorporated into classroom biology discussions. Examples of several parasitic diseases and their ecological significance are provided. (JN)

Illustrating the Interaction of Nature and People in Ecosystem Services: The Case of Terroir in Wine

NASA Astrophysics Data System (ADS)

Nicholas, K. A.

2014-12-01

The ecosystem services (ES) approach is increasingly used in research and policy, with the Common International Framework on Ecosystem Services (CICES) "cascade" gaining traction as a framework for conceptualizing the production of ecosystem services by the natural environment, and then people consuming these services and obtaining benefits depending on their values. However, uptake of the ES concept on the ground by ecosystem managers, and understanding by everyday citizens, is still limited. One barrier is the challenge of providing tangible, examples of everyday benefits and values that people can readily connect with the biophysical structures and functions that underlie their provision. Winegrowing offers one promising case to illustrate the linkages all along the chain of production and consumption of ecosystem services. The sensitive winegrape has long been known for its properties of terroir, where the taste of wine reflects the environmental conditions of the place where it is grown, a feature valued by consumers. Here the CICES framework is illustrated with the case of winegrowing, demonstrating that the current linear model of natural production and human consumption of ES needs to be modified for this case because people influence each of the five stages by shaping and responding to their environment, producing a two-way interaction between people and the environment throughout. For example, while natural drivers such as climate and soils are key to the provision of the service of winegrape yields, landowners modify the biophysical environment through site selection and growers modify plant ecophysiological function through farming practices such as pruning and irrigation in order to influence the final service. Similarly, winemakers' expertise is needed to transform the service of winegrape yields into the product of wine that can be enjoyed and valued by consumers, whose preferences shape wine styles as well. This case illustrates how incorporating both natural and human factors all along the chain of production and consumption of ecosystem services can better represent the potential services provided, and highlights the need to identify relevant decisionmakers at each stage to better understand and manage ecosystem services under environmental change.

Habitability as a Tier One Criterion in Exploration Mission and Vehicle Design. Part 1; Habitability

NASA Technical Reports Server (NTRS)

Adams, Constance M.; McCurdy, Matthew Riegel

1999-01-01

Habitability and human factors are necessary criteria to include in the iterative process of Tier I mission design. Bringing these criteria in at the first, conceptual stage of design for exploration and other human-rated missions can greatly reduce mission development costs, raise the level of efficiency and viability, and improve the chances of success. In offering a rationale for this argument, the authors give an example of how the habitability expert can contribute to early mission and vehicle architecture by defining the formal implications of a habitable vehicle, assessing the viability of units already proposed for exploration missions on the basis of these criteria, and finally, by offering an optimal set of solutions for an example mission. In this, the first of three papers, we summarize the basic factors associated with habitability, delineate their formal implications for crew accommodations in a long-duration environment, and show examples of how these principles have been applied in two projects at NASA's Johnson Space Center: the BIO-Plex test facility, and TransHab.

MO-F-16A-04: Case Study: Estimation of Peak Skin Dose Following a Physician Reported “High Dose” Case and Sentinel Event Considerations

DOE Office of Scientific and Technical Information (OSTI.GOV)

Supanich, M; Chu, J; Wehmeyer, A

2014-06-15

Purpose: This work offers as a teaching example a reported high dose fluoroscopy case and the workflow the institution followed to self-report a radiation overdose sentinel event to the Joint Commission. Methods: Following the completion of a clinical case in a hybrid OR room with a reported air kerma of >18 Gy at the Interventional Reference Point (IRP) the physicians involved in the case referred study to the institution's Radiation Safety Committee (RSC) for review. The RSC assigned a Diagnostic Medical Physicist (DMP) to estimate the patient's Peak Skin Dose (PSD) and analyze the case. Following the DMP's analysis andmore » estimate of a PSD of >15 Gy the institution's adverse event committee was convened to discuss the case and to self-report the case as a radiation overdose sentinel event to the Joint Commission. The committee assigned a subgroup to perform the root cause analysis and develop institutional responses to the event. Results: The self-reporting of the sentinel event and the associated root cause analysis resulted in several institutional action items that are designed to improve process and safety. A formal reporting and analysis mechanism was adopted to review fluoroscopy cases with air kerma greater than 6 Gy at the IRP. An improved and formalized radiation safety training program for physicians using fluoroscopy equipment was implemented. Additionally efforts already under way to monitor radiation exposure in the Radiology department were expanded to include all fluoroscopy equipment capable of automated dose reporting. Conclusion: The adverse event review process and the root cause analysis following the self-reporting of the sentinel event resulted in policies and procedures that are expected to improve the quality and safe usage of fluoroscopy throughout the institution.« less

Virtual patients in continuing medical education and residency training: a pilot project for acceptance analysis in the framework of a residency revision course in pediatrics.

PubMed

Lehmann, Ronny; Hanebeck, Benjamin; Oberle, Stephan; Simon, Anke; Choukair, Daniela; Tönshoff, Burkhard; Huwendiek, Sören

2015-01-01

Virtual patients (VPs) are a one-of-a-kind e-learning resource, fostering clinical reasoning skills through clinical case examples. The combination with face-to-face teaching is important for their successful integration, which is referred to as "blended learning". So far little is known about the use of VPs in the field of continuing medical education and residency training. The pilot study presented here inquired the application of VPs in the framework of a pediatric residency revision course. Around 200 participants of a pediatric nephology lecture ('nephrotic and nephritic syndrome in children') were offered two VPs as a wrap-up session at the revision course of the German Society for Pediatrics and Adolescent Medicine (DGKJ) 2009 in Heidelberg, Germany. Using a web-based survey form, different aspects were evaluated concerning the learning experiences with VPs, the combination with the lecture, and the use of VPs for residency training in general. N=40 evaluable survey forms were returned (approximately 21%). The return rate was impaired by a technical problem with the local Wi-Fi firewall. The participants perceived the work-up of the VPs as a worthwhile learning experience, with proper preparation for diagnosing and treating real patients with similar complaints. Case presentations, interactivity, and locally and timely independent repetitive practices were, in particular, pointed out. On being asked about the use of VPs in general for residency training, there was a distinct demand for more such offers. VPs may reasonably complement existing learning activities in residency training.

Web portal on environmental sciences "ATMOS''

NASA Astrophysics Data System (ADS)

Gordov, E. P.; Lykosov, V. N.; Fazliev, A. Z.

2006-06-01

The developed under INTAS grant web portal ATMOS (http://atmos.iao.ru and http://atmos.scert.ru) makes available to the international research community, environmental managers, and the interested public, a bilingual information source for the domain of Atmospheric Physics and Chemistry, and the related application domain of air quality assessment and management. It offers access to integrated thematic information, experimental data, analytical tools and models, case studies, and related information and educational resources compiled, structured, and edited by the partners into a coherent and consistent thematic information resource. While offering the usual components of a thematic site such as link collections, user group registration, discussion forum, news section etc., the site is distinguished by its scientific information services and tools: on-line models and analytical tools, and data collections and case studies together with tutorial material. The portal is organized as a set of interrelated scientific sites, which addressed basic branches of Atmospheric Sciences and Climate Modeling as well as the applied domains of Air Quality Assessment and Management, Modeling, and Environmental Impact Assessment. Each scientific site is open for external access information-computational system realized by means of Internet technologies. The main basic science topics are devoted to Atmospheric Chemistry, Atmospheric Spectroscopy and Radiation, Atmospheric Aerosols, Atmospheric Dynamics and Atmospheric Models, including climate models. The portal ATMOS reflects current tendency of Environmental Sciences transformation into exact (quantitative) sciences and is quite effective example of modern Information Technologies and Environmental Sciences integration. It makes the portal both an auxiliary instrument to support interdisciplinary projects of regional environment and extensive educational resource in this important domain.

Harnessing Implementation Science to Increase the Impact of Health Disparity Research

PubMed Central

Chinman, Matthew; Woodward, Eva N.; Curran, Geoffrey M.; Hausmann, Leslie R. M.

2017-01-01

Background Health disparities are differences in health or health care between groups based on social, economic, and/or environmental disadvantage. Disparity research often follows three steps: detecting (Phase 1), understanding (Phase 2), and reducing (Phase 3), disparities. While disparities have narrowed over time, many remain. Objectives We argue that implementation science could enhance disparities research by broadening the scope of Phase 2 studies and offering rigorous methods to test disparity-reducing implementation strategies in Phase 3 studies. Methods We briefly review the focus of Phase 2 and Phase 3 disparities research. We then provide a decision tree and case examples to illustrate how implementation science frameworks and research designs could further enhance disparity research. Results Most health disparities research emphasizes patient and provider factors as predominant mechanisms underlying disparities. Applying implementation science frameworks like the Consolidated Framework for Implementation Research could help disparities research widen its scope in Phase 2 studies and, in turn, develop broader disparities-reducing implementation strategies in Phase 3 studies. Many Phase 3 studies of disparity reducing implementation strategies are similar to case studies, whose designs are not able to fully test causality. Implementation science research designs offer rigorous methods that could accelerate the pace at which equity is achieved in real world practice. Conclusions Disparities can be considered a “special case” of implementation challenges—when evidence-based clinical interventions are delivered to, and received by, vulnerable populations at lower rates. Bringing together health disparities research and implementation science could advance equity more than either could achieve on their own. PMID:28806362

Examples and Case Studies for the 2012 Chemical Data Reporting

EPA Pesticide Factsheets

This document presents examples and case studies to help you in reporting for 2012 Chemical Data Reporting (CDR), formerly known as Inventory Update Reporting (IUR).EPA designed these examples to illustrate the new reporting requirements, which were published as part of the CDR Rule (published August 16, 2011), and to address general reporting issues from the 2006 IUR.

Crafty Corner.

ERIC Educational Resources Information Center

Naturescope, 1986

1986-01-01

Presents step-by-step procedures for two arts and crafts lessons that focus on mammals. Directions are offered for making mammal-shaped dough magnets and also for creating mammal note cards. Examples of each are illustrated. (ML)

Transportation systems health : concepts, applications & significance.

DOT National Transportation Integrated Search

2015-12-01

This report offers conceptual and analytical frameworks and application examples to address the question: how can broader statewide (or national) objectives be achieved while formally taking into consideration different regional priorities and constr...

Utilities Expense Report.

ERIC Educational Resources Information Center

Moore, Deborah P.

2001-01-01

Examines how deregulation has affected school district utility costs. Offers ideas that can help school districts save money and energy. Provides several examples of state-wide initiatives intended to help school districts control utility costs. (GR)

Observational evidence and strength of evidence domains: case examples

PubMed Central

2014-01-01

Background Systematic reviews of healthcare interventions most often focus on randomized controlled trials (RCTs). However, certain circumstances warrant consideration of observational evidence, and such studies are increasingly being included as evidence in systematic reviews. Methods To illustrate the use of observational evidence, we present case examples of systematic reviews in which observational evidence was considered as well as case examples of individual observational studies, and how they demonstrate various strength of evidence domains in accordance with current Agency for Healthcare Research and Quality (AHRQ) Evidence-based Practice Center (EPC) methods guidance. Results In the presented examples, observational evidence is used when RCTs are infeasible or raise ethical concerns, lack generalizability, or provide insufficient data. Individual study case examples highlight how observational evidence may fulfill required strength of evidence domains, such as study limitations (reduced risk of selection, detection, performance, and attrition); directness; consistency; precision; and reporting bias (publication, selective outcome reporting, and selective analysis reporting), as well as additional domains of dose-response association, plausible confounding that would decrease the observed effect, and strength of association (magnitude of effect). Conclusions The cases highlighted in this paper demonstrate how observational studies may provide moderate to (rarely) high strength evidence in systematic reviews. PMID:24758494

Time to address gender discrimination and inequality in the health workforce

PubMed Central

2014-01-01

Gender is a key factor operating in the health workforce. Recent research evidence points to systemic gender discrimination and inequalities in health pre-service and in-service education and employment systems. Human resources for health (HRH) leaders’ and researchers’ lack of concerted attention to these inequalities is striking, given the recognition of other forms of discrimination in international labour rights and employment law discourse. If not acted upon, gender discrimination and inequalities result in systems inefficiencies that impede the development of the robust workforces needed to respond to today’s critical health care needs. This commentary makes the case that there is a clear need for sex- and age-disaggregated and qualitative data to more precisely illuminate gender-related trends and dynamics in the health workforce. Because of their importance for measurement, the paper also presents definitions and examples of sex or gender discrimination and offers specific case examples. At a broader level, the commentary argues that gender equality should be an HRH research, leadership, and governance priority, where the aim is to strengthen health pre-service and continuing professional education and employment systems to achieve better health systems outcomes, including better health coverage. Good HRH leadership, governance, and management involve recognizing the diversity of health workforces, acknowledging gender constraints and opportunities, eliminating gender discrimination and equalizing opportunity, making health systems responsive to life course events, and protecting health workers’ labour rights at all levels. A number of global, national and institution-level actions are proposed to move the gender equality and HRH agendas forward. PMID:24885565

Equifinality in empirical studies of cultural transmission.

PubMed

Barrett, Brendan J

2018-01-31

Cultural systems exhibit equifinal behavior - a single final state may be arrived at via different mechanisms and/or from different initial states. Potential for equifinality exists in all empirical studies of cultural transmission including controlled experiments, observational field research, and computational simulations. Acknowledging and anticipating the existence of equifinality is important in empirical studies of social learning and cultural evolution; it helps us understand the limitations of analytical approaches and can improve our ability to predict the dynamics of cultural transmission. Here, I illustrate and discuss examples of equifinality in studies of social learning, and how certain experimental designs might be prone to it. I then review examples of equifinality discussed in the social learning literature, namely the use of s-shaped diffusion curves to discern individual from social learning and operational definitions and analytical approaches used in studies of conformist transmission. While equifinality exists to some extent in all studies of social learning, I make suggestions for how to address instances of it, with an emphasis on using data simulation and methodological verification alongside modern statistical approaches that emphasize prediction and model comparison. In cases where evaluated learning mechanisms are equifinal due to non-methodological factors, I suggest that this is not always a problem if it helps us predict cultural change. In some cases, equifinal learning mechanisms might offer insight into how both individual learning, social learning strategies and other endogenous social factors might by important in structuring cultural dynamics and within- and between-group heterogeneity. Copyright © 2018 Elsevier B.V. All rights reserved.

Time to address gender discrimination and inequality in the health workforce.

PubMed

Newman, Constance

2014-05-06

Gender is a key factor operating in the health workforce. Recent research evidence points to systemic gender discrimination and inequalities in health pre-service and in-service education and employment systems. Human resources for health (HRH) leaders' and researchers' lack of concerted attention to these inequalities is striking, given the recognition of other forms of discrimination in international labour rights and employment law discourse. If not acted upon, gender discrimination and inequalities result in systems inefficiencies that impede the development of the robust workforces needed to respond to today's critical health care needs.This commentary makes the case that there is a clear need for sex- and age-disaggregated and qualitative data to more precisely illuminate gender-related trends and dynamics in the health workforce. Because of their importance for measurement, the paper also presents definitions and examples of sex or gender discrimination and offers specific case examples.At a broader level, the commentary argues that gender equality should be an HRH research, leadership, and governance priority, where the aim is to strengthen health pre-service and continuing professional education and employment systems to achieve better health systems outcomes, including better health coverage. Good HRH leadership, governance, and management involve recognizing the diversity of health workforces, acknowledging gender constraints and opportunities, eliminating gender discrimination and equalizing opportunity, making health systems responsive to life course events, and protecting health workers' labour rights at all levels. A number of global, national and institution-level actions are proposed to move the gender equality and HRH agendas forward.

a Web-Based Interactive Tool for Multi-Resolution 3d Models of a Maya Archaeological Site

NASA Astrophysics Data System (ADS)

Agugiaro, G.; Remondino, F.; Girardi, G.; von Schwerin, J.; Richards-Rissetto, H.; De Amicis, R.

2011-09-01

Continuous technological advances in surveying, computing and digital-content delivery are strongly contributing to a change in the way Cultural Heritage is "perceived": new tools and methodologies for documentation, reconstruction and research are being created to assist not only scholars, but also to reach more potential users (e.g. students and tourists) willing to access more detailed information about art history and archaeology. 3D computer-simulated models, sometimes set in virtual landscapes, offer for example the chance to explore possible hypothetical reconstructions, while on-line GIS resources can help interactive analyses of relationships and change over space and time. While for some research purposes a traditional 2D approach may suffice, this is not the case for more complex analyses concerning spatial and temporal features of architecture, like for example the relationship of architecture and landscape, visibility studies etc. The project aims therefore at creating a tool, called "QueryArch3D" tool, which enables the web-based visualisation and queries of an interactive, multi-resolution 3D model in the framework of Cultural Heritage. More specifically, a complete Maya archaeological site, located in Copan (Honduras), has been chosen as case study to test and demonstrate the platform's capabilities. Much of the site has been surveyed and modelled at different levels of detail (LoD) and the geometric model has been semantically segmented and integrated with attribute data gathered from several external data sources. The paper describes the characteristics of the research work, along with its implementation issues and the initial results of the developed prototype.

Research-to-policy translation for prevention of disordered weight and shape control behaviors: A case example targeting dietary supplements sold for weight loss and muscle building.

PubMed

Austin, S Bryn; Yu, Kimberly; Tran, Alvin; Mayer, Beth

2017-04-01

New approaches to universal eating disorders prevention and interventions targeting macro-environmental change are greatly needed, and research-to-policy translation efforts hold promise for advancing both of these goals. This paper describes as a policy-translation case example an academic-community-government partnership of the Strategic Training Initiative for the Prevention of Eating Disorders, Multi-Service Eating Disorders Association, and the office of Massachusetts Representative Kay Khan, all based in Massachusetts, USA. The partnership's research-to-policy translation project focused on dietary supplements sold for weight loss and muscle building, which have been linked with serious injury and death in consumers. Youth and people of all ages with eating disorders and body dysmorphic disorder may be especially vulnerable to use these products due to deceptive promises of fast and safe weight loss and muscle gain. The research-to-policy translation project was informed by a triggers-to-action framework to establish the evidentiary base of harm to consumers, operationalize policy solutions to mitigate harm through legislation, and generate political will to support action through legislation introduced in the Massachusetts legislature to restrict sales of weight-loss and muscle-building dietary supplements. The paper concludes with lessons learned from this unique policy translation effort for the prevention of disordered weight and shape control behaviors and offers recommendations for next steps for the field to advance research and practice for universal, macro-environmentally targeted prevention. Copyright © 2016 Elsevier Ltd. All rights reserved.

PUMAS (Practical Uses of Math And Science) - Low Cost, High Impact

NASA Astrophysics Data System (ADS)

Kahn, R. A.

2004-12-01

PUMAS is an on-line journal, aimed at giving pre-college teachers brief examples showing how math and science topics taught in K-12 classes can be used in interesting settings, including everyday life. The concept is a simple one - (1) ask scientists, engineers, and other content experts to write up their favorite examples of practical uses, (2) ask the authors to key their examples to the National Standards and Benchmarks, so the material is grade-appropriate and useful in the classroom, (3) have each example peer-reviewed by at least one scientist with a relevant background, and at least one teacher at an appropriate grade level, helping keep an emphasis on quality, and (4) disseminate the examples widely and inexpensively through the PUMAS Web Site (http://pumas.jpl.nasa.gov). PUMAS examples may be activities, anecdotes, descriptions of "neat ideas," formal exercises, puzzles, or demonstrations; each one is a gem, written in the voice of its author. The PUMAS site also provides opportunities for feedback on individual examples and on the journal as a whole. As with most scientific journals, the writing, reviewing, and editing efforts are volunteered; they leverage the "community service" offered by so many teachers and scientists. We have streamlined all aspects of the example submission, review, and search processes so participants can contribute at a high level, with a minimum of extraneous effort. The primary PUMAS operating expenses cover Web Site technical maintenance and computer security. The PUMAS site receives several thousand unique queries per week, and publishes an average of about one new example per month. Maintaining a strong user base has been helped by endorsements from such organizations as the NSTA and NCTM. To contributors we offer an avenue for making a real impact on pre-college education with a relatively small time commitment, and the opportunity for peer-reviewed publication. We are always looking for good examples of the Practical Uses of Math And Science. This work is performed at the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space Administration.

Examining Preservice Teachers' Decision Behaviors and Individual Differences in Three Online Case-Based Approaches

ERIC Educational Resources Information Center

Cevik, Yasemin Demiraslan; Andre, Thomas

2013-01-01

This study compared the impact of three types of case-based methods (case-based reasoning, worked example, and faded worked example) on preservice teachers' (n = 71) interaction with decision tasks and whether decision related measures (task difficulty, mental effort, decision making performance) were associated with the differences in student…

What the comprehensive economics of blindness and visual impairment can help us understand

PubMed Central

Frick, Kevin D

2012-01-01

Since the year 2000, the amount written about the economics of blindness and visual impairment has increased substantially. In some cases, the studies listed under this heading are calculations of the costs related to vision impairment and blindness at a national or global level; in other cases the studies examine the cost-effectiveness of strategies to prevent or modify visual impairment or blindness that are intended to be applied as a guide to treatment recommendations and coverage decisions. In each case the references are just examples of many that could be cited. These important studies have helped advocates, policy makers, practitioners, educators, and others interested in eye and vision health to understand the magnitude of the impact that visual impairment and blindness have on the world, regions, nations, and individuals and the tradeoffs that need to be made to limit the impact. However, these studies only begin to tap into the insights that economic logic might offer to those interested in this field. This paper presents multiple case studies that demonstrate that the economics of blindness and visual impairment encompasses much more than simply measures of the burden of the condition. Case studies demonstrating the usefulness of economic insight include analysis of the prevention of conditions that lead to impairment, decisions about refractive error and presbyopia, decisions about disease and injury treatment, decisions about behavior among those with uncorrectable impairment, and decisions about how to regulate the market all have important economic inputs. PMID:22944750

What the comprehensive economics of blindness and visual impairment can help us understand.

PubMed

Frick, Kevin D

2012-01-01

Since the year 2000, the amount written about the economics of blindness and visual impairment has increased substantially. In some cases, the studies listed under this heading are calculations of the costs related to vision impairment and blindness at a national or global level; in other cases the studies examine the cost-effectiveness of strategies to prevent or modify visual impairment or blindness that are intended to be applied as a guide to treatment recommendations and coverage decisions. In each case the references are just examples of many that could be cited. These important studies have helped advocates, policy makers, practitioners, educators, and others interested in eye and vision health to understand the magnitude of the impact that visual impairment and blindness have on the world, regions, nations, and individuals and the tradeoffs that need to be made to limit the impact. However, these studies only begin to tap into the insights that economic logic might offer to those interested in this field. This paper presents multiple case studies that demonstrate that the economics of blindness and visual impairment encompasses much more than simply measures of the burden of the condition. Case studies demonstrating the usefulness of economic insight include analysis of the prevention of conditions that lead to impairment, decisions about refractive error and presbyopia, decisions about disease and injury treatment, decisions about behavior among those with uncorrectable impairment, and decisions about how to regulate the market all have important economic inputs.

Virtual lab for learning equipment and treatment of experimental measurements of rainfall, runoff and erosion in small rural catchments

NASA Astrophysics Data System (ADS)

Ángel Bajo, José; Redel-Macías, María Dolores; Nichols, Mary; Pérez, Rafael; Bellido, Francisco; Marín-Moreno, Víctor; Taguas, Encarnación V.

2017-04-01

A virtual lab for learning to use devices and to treat experimental measurements of hydrological and erosive processes in small agricultural catchments was created to support the practical content of the subject Restoration of Forest Ecosystems of the Master of Forest Engineer (University of Cordoba). The objective was to build a virtual place representing a real site equipped to make measurements of rainfall, runoff and sediment concentration. The virtual lab included pictures, videos and explanations that facilitate learning. Moreover, some practical cases were proposed to apply the explained terms. The structure of menu consisted of: Experimental measurements in catchments; Gallery of videos; Equipment; Practical case; Glossary and Additional Information. Their contents were carefully carried out by professors and scientists of Hydrology and Electronics. The main advantages of the virtual lab were its compatibility with on-line platforms such as Moodle and the presentation of examples for the direct analysis as a basis for solving the proposed practical cases. It has been successfully used for two years and was well-values by the students due the opportunities offered by self-access learning tools. In addition, constraints associated with field trips such as logistical complexity and economic aspects are removed.

Emotions and Strategic Behaviour: The Case of the Ultimatum Game.

PubMed

Tamarit, Ignacio; Sánchez, Angel

2016-01-01

Human behaviour in economic interactions has attracted an increasing amount of attention over the last decades. The economic assumption that people would behave focusing on their own material self-interest was proved incomplete, once the empirical evidence consistently showed that many other motives may influence such behaviour. Therefore, models that can incorporate rational decision process as well as other intervening factors are a key issue to both understand the observations from economic experiments and to apply the lessons learned from them. In this paper, we incorporate the influence of emotions to the utility function in an explicit manner, using the Ultimatum Game as a case study. Our model is amenable to analytical study, and is connected with the Circumplex model of emotions and with Kahneman's two-system theory. The simplicity of the model allows to obtain predictions for the offers and acceptance thresholds. We study two specific examples, when the model parameters are distributed uniformly or normally, and show that in the latter case the results are already qualitatively correct. Although this work can be considered as a first approach, it includes what we believe are the main stylized facts, is able to qualitatively reproduce experimental results in a very simple manner, and can be straightforwardly extended to other games.

Novel flood risk assessment framework for rapid decision making

NASA Astrophysics Data System (ADS)

Valyrakis, Manousos; Koursari, Eftychia; Solley, Mark

2016-04-01

The impacts of catastrophic flooding, have significantly increased over the last few decades. This is due to primarily the increased urbanisation in ever-expanding mega-cities as well as due to the intensification both in magnitude and frequency of extreme hydrologic events. Herein a novel conceptual framework is presented that incorporates the use of real-time information to inform and update low dimensionality hydraulic models, to allow for rapid decision making towards preventing loss of life and safeguarding critical infrastructure. In particular, a case study from the recent UK floods in the area of Whitesands (Dumfries), is presented to demonstrate the utility of this approach. It is demonstrated that effectively combining a wealth of readily available qualitative information (such as crowdsourced visual documentation or using live data from sensing techniques), with existing quantitative data, can help appropriately update hydraulic models and reduce modelling uncertainties in future flood risk assessments. This approach is even more useful in cases where hydraulic models are limited, do not exist or were not needed before unpredicted dynamic modifications to the river system took place (for example in the case of reduced or eliminated hydraulic capacity due to blockages). The low computational cost and rapid assessment this framework offers, render it promising for innovating in flood management.

Generic project definitions for improvement of health care delivery: a case-based approach.

PubMed

Niemeijer, Gerard C; Does, Ronald J M M; de Mast, Jeroen; Trip, Albert; van den Heuvel, Jaap

2011-01-01

The purpose of this article is to create actionable knowledge, making the definition of process improvement projects in health care delivery more effective. This study is a retrospective analysis of process improvement projects in hospitals, facilitating a case-based reasoning approach to project definition. Data sources were project documentation and hospital-performance statistics of 271 Lean Six Sigma health care projects from 2002 to 2009 of general, teaching, and academic hospitals in the Netherlands and Belgium. Objectives and operational definitions of improvement projects in the sample, analyzed and structured in a uniform format and terminology. Extraction of reusable elements of earlier project definitions, presented in the form of 9 templates called generic project definitions. These templates function as exemplars for future process improvement projects, making the selection, definition, and operationalization of similar projects more efficient. Each template includes an explicated rationale, an operationalization in the form of metrics, and a prototypical example. Thus, a process of incremental and sustained learning based on case-based reasoning is facilitated. The quality of project definitions is a crucial success factor in pursuits to improve health care delivery. We offer 9 tried and tested improvement themes related to patient safety, patient satisfaction, and business-economic performance of hospitals.

Emotions and Strategic Behaviour: The Case of the Ultimatum Game

PubMed Central

Sánchez, Angel

2016-01-01

Human behaviour in economic interactions has attracted an increasing amount of attention over the last decades. The economic assumption that people would behave focusing on their own material self-interest was proved incomplete, once the empirical evidence consistently showed that many other motives may influence such behaviour. Therefore, models that can incorporate rational decision process as well as other intervening factors are a key issue to both understand the observations from economic experiments and to apply the lessons learned from them. In this paper, we incorporate the influence of emotions to the utility function in an explicit manner, using the Ultimatum Game as a case study. Our model is amenable to analytical study, and is connected with the Circumplex model of emotions and with Kahneman’s two-system theory. The simplicity of the model allows to obtain predictions for the offers and acceptance thresholds. We study two specific examples, when the model parameters are distributed uniformly or normally, and show that in the latter case the results are already qualitatively correct. Although this work can be considered as a first approach, it includes what we believe are the main stylized facts, is able to qualitatively reproduce experimental results in a very simple manner, and can be straightforwardly extended to other games. PMID:27385254

"No More Bologna Sandwiches."

ERIC Educational Resources Information Center

Book, Daisy; And Others

1990-01-01

The article describes a six-week cooking program for developmentally disabled adults offered through the county continuing education program. The program utilizes illustrated recipes (an example is included). Significant outcomes and implementation pointers are noted. (DB)

Helping Emotionally Disturbed Children Deal with the Separation Process.

ERIC Educational Resources Information Center

Kreger, Robert D.; Kreger, Linda R.

1989-01-01

The article presents examples of emotionally disturbed children's reactions to separation from a teacher with whom they have become involved. Suggestions are offered for facilitating healthy separation from the teacher. (JDD)

Taking a Case Method Capstone Course Online: A Comparative Case Study

ERIC Educational Resources Information Center

Gill, T. Grandon; Mullarkey, Matthew T.

2015-01-01

A capstone course is normally offered at the end of a program of study with the goal of helping students synthesize what they have learned in the courses preceding it. The paper describes such a course--an undergraduate capstone course for MIS majors--that was built around case discussions and projects and originally offered in a face-to-face…

Identifying Barriers to Knowledge Management in the US Military

DTIC Science & Technology

2002-12-16

research as: ethnographies , grounded theory , case studies , and phenomenological studies . Myers (1997) offers a slightly...different view offering that the more common qualitative research designs include action research , case study research , and ethnography . Regardless of...many meanings. “It can be used to describe a unit of analysis (e.g., a case study of a particular organization) or to describe a

Survey highlights the need to expand offerings of introductory pharmacy practice experiences in psychiatry and neurology: Benefits and example experiences

PubMed Central

2018-01-01

Introduction: Introductory pharmacy practice experiences (IPPEs) are 1 requirement schools and colleges of pharmacy must fulfill to meet accreditation standards. The purpose of this manuscript is to report existing IPPEs in psychiatry and neurology across the United States. Methods: Two separate electronic surveys were administered to individual College of Psychiatric and Neurologic Pharmacists members with board certification in psychiatric pharmacy with an academic affiliation and academic institutions in the 2014-15 academic year to assess the neuropsychiatric curriculum in pharmacy programs. Results focusing on IPPEs were summarized using descriptive statistics. Results: Academic institutional data reveal only 37.3% offered IPPEs in psychiatry, and 6.7% offered neurology. The number of available IPPEs is low even if a program offered an available rotation. The majority of College of Psychiatric and Neurologic Pharmacists member respondents (69.9%) did not offer IPPEs in psychiatry in the 2014-15 academic year, and none offered an IPPE in neurology. More than half of individual respondents feel their institution should increase IPPEs in psychiatry and neurology in order to enhance their curriculum. Discussion: To expand IPPE availability, pharmacy programs should increase early exposure of pharmacy students to patients with psychiatric and neurologic conditions. Longitudinal experiences may allow students to engage in hands-on experiences, which may impact future career aspirations and reduce stigma. Current example IPPEs at the authors' institutions are included to stimulate discussion and action among readers on how IPPEs in these practice areas may be developed. Implementation of IPPEs in psychiatry and neurology is needed for students to gain experience working with these patients. PMID:29955538

Medical electronics: A need and a challenge

NASA Technical Reports Server (NTRS)

Dimeoff, J.

1973-01-01

Space programs have led to the development of telemetry pills for diagnosis of diseases of the digestive tract, reusable X-ray image storage plates that require no chemical processing, and muscular augmentation systems for the handicapped. These examples, together with countless other examples of technological innovation that can be drawn from research and development programs supported by government funds, offer a potential opportunity to stimulate growth and to control rising costs in medical electronics.

Scientist Participation in Education and Public Outreach - Using Web Tools to Communicate the Scientific Process and Engage an Audience in Understanding Planetary Science: Examples with Lunar Reconnaissance Orbiter (LRO) Data (Invited)

NASA Astrophysics Data System (ADS)

Petro, N. E.

2013-12-01

Scientists often speak to the public about their science and the current state of understanding of their field. While many talks (including those by this author) typically feature static plots, figures, diagrams, and the odd movie/animation/visualization (when technology allows), it is now possible, using the web to guide an audience through the thought process of how a scientist tackles certain questions. The presentation will highlight examples of web tools that effectively illustrate how datasets are used to address questions of lunar science. Why would a scientist use precious time during a talk to interact with data, in real time? Why not just show the results and move on? Through experience it is evident that illustrating how data is analyzed, even in a simple form, engages an audience, and demonstrates the thought process when interacting with data. While it is clear that scientists are unlikely to use such a tool to conduct science, it illustrates how a member of the public can engage with mission data. An example is discussed below. When discussing the geology of the Moon, there is an enormous volume of data that can be used to explain what we know (or think we know) and how we know it. For example, the QuickMap interface (http://www.actgate.com/home/quickmap.htm) enables interaction with a set of data (images, spectral data, topography, radar data) across the entire Moon (http://target.lroc.asu.edu/q3/). This webtool enables a speaker the opportunity (given adequate web connectivity) to talk about features, such as a crater, and show it from multiple perspectives (e.g., plan view, oblique, topographically exaggerated) in a logical flow. The tool enables illustration of topographic profiles, 3-D perspectives, and data overlays. Now, one might ask why doing this demonstration in real time is valuable, over a set of static slides. In some cases static slides are best, and doing any real time demos is unfeasible. However, guiding an engaged audience through the thought process, in real time, also offers the audience the opportunity to interact with both the scientist and the data. When a presenter offers the audience the chance to identify a target to explore, the presentation becomes a two-way dialog and guided discussion, over a lecture with little interaction. The demonstration also allows for questions of what additional data is needed or desired to address a given question. All told, this is a method for illustrating how a scientist (primarily interested in remote sensing) can use an available tool to walk through how a focused science question can be addressed, or how typical analysis are conducted. For example, one can show how, for a small set of craters, the depth-diameter ratio varies as a function of degradation. This leads to the question of why, and hopefully a discussion of the erosion process on the Moon. Additional examples will be discussed and illustrated. Example of Quickmap interface illustrating perspective view of Tycho Crater.

Examining Preservice Teachers' Classroom Management Decisions in Three Case-Based Teaching Approaches

ERIC Educational Resources Information Center

Cevik, Yasemin Demiraslan; Andre, Thomas

2013-01-01

This study was aimed at comparing the impact of three types of case-based approaches (worked example, faded work example, and case-based reasoning) on preservice teachers' decision making and reasoning skills related to realistic classroom management situations. Participants in this study received a short-term implementation of one of these three…

The Double Feature of Musical "Folkbildning": Three Swedish Examples

ERIC Educational Resources Information Center

Brandstrom, Sture; Soderman, Johan; Thorgersen, Ketil

2012-01-01

The purpose of this article is to analyse three case study examples of musical "folkbildning" in Sweden. The first case study is from the establishment of the state-funded Framnas Folk High Music School in the middle of the last century. The second case study, Hagstrom's music education, is from the same time but describes a music school…

Qualitative case study data analysis: an example from practice.

PubMed

Houghton, Catherine; Murphy, Kathy; Shaw, David; Casey, Dympna

2015-05-01

To illustrate an approach to data analysis in qualitative case study methodology. There is often little detail in case study research about how data were analysed. However, it is important that comprehensive analysis procedures are used because there are often large sets of data from multiple sources of evidence. Furthermore, the ability to describe in detail how the analysis was conducted ensures rigour in reporting qualitative research. The research example used is a multiple case study that explored the role of the clinical skills laboratory in preparing students for the real world of practice. Data analysis was conducted using a framework guided by the four stages of analysis outlined by Morse ( 1994 ): comprehending, synthesising, theorising and recontextualising. The specific strategies for analysis in these stages centred on the work of Miles and Huberman ( 1994 ), which has been successfully used in case study research. The data were managed using NVivo software. Literature examining qualitative data analysis was reviewed and strategies illustrated by the case study example provided. Discussion Each stage of the analysis framework is described with illustration from the research example for the purpose of highlighting the benefits of a systematic approach to handling large data sets from multiple sources. By providing an example of how each stage of the analysis was conducted, it is hoped that researchers will be able to consider the benefits of such an approach to their own case study analysis. This paper illustrates specific strategies that can be employed when conducting data analysis in case study research and other qualitative research designs.

An approach to decision-making with triangular fuzzy reciprocal preference relations and its application

NASA Astrophysics Data System (ADS)

Meng, Fanyong

2018-02-01

Triangular fuzzy reciprocal preference relations (TFRPRs) are powerful tools to denoting decision-makers' fuzzy judgments, which permit the decision-makers to apply triangular fuzzy ratio rather than real numbers to express their judgements. Consistency analysis is one of the most crucial issues in preference relations that can guarantee the reasonable ranking order. However, all previous consistency concepts cannot well address this type of preference relations. Based on the operational laws on triangular fuzzy numbers, this paper introduces an additive consistency concept for TFRPRs by using quasi TFRPRs, which can be seen as a natural extension of the crisp case. Using this consistency concept, models to judging the additive consistency of TFRPRs and to estimating missing values in complete TFRPRs are constructed. Then, an algorithm to decision-making with TFRPRs is developed. Finally, two numerical examples are offered to illustrate the application of the proposed procedure, and comparison analysis is performed.

The RWJ Executive Nurse Fellows Program, Part 2: Mentoring for leadership success.

PubMed

Bellack, Janis P; Morjikian, Robin L

2005-12-01

This article is the second in a 3-part series describing the RWJ Executive Nurse Fellows Program, an advanced leadership program for nurses in senior executive roles who aspire to help lead and shape the US healthcare system of the future. Part 1 (October 2005) described the program, its core leadership competencies, and the primary components. This article discusses the mentor experience that is a cornerstone of the 3-year fellowship program. Fellows are encouraged to have this experience with senior-level executives outside of healthcare in order to broaden their leadership perspectives. Examples of these mentor experiences are described from the viewpoints of both fellows and mentors, including successes, challenges, and lessons learned. Part 3 (February 2006) will explain how fellows are required to create a business plan for their leadership project because it is so important for nurse leaders to offer a strong business case for proceeding with anew initiative, service, or program.

Pizza again? On the division of polygons into sections with a common origin

NASA Astrophysics Data System (ADS)

Sinitsky, Ilya; Stupel, Moshe; Sinitsky, Marina

2018-02-01

The paper explores the division of a polygon into equal-area pieces using line segments originating at a common point. The mathematical background of the proposed method is very simple and belongs to secondary school geometry. Simple examples dividing a square into two, four or eight congruent pieces provide a starting point to discovering how to divide a regular polygon into any number of equal-area pieces using line segments originating from the centre. Moreover, it turns out that there are infinite ways to do the division. Discovering the basic invariant involved allows application of the same procedure to divide any tangential polygon, as after suitable adjustment, it can be used also for rectangles and parallelograms. Further generalization offers many additional solutions of the problem, and some of them are presented for the case of an arbitrary triangle and a square. Links to dynamic demonstrations in GeoGebra serve to illustrate the main results.

Key Reconciliation for High Performance Quantum Key Distribution

PubMed Central

Martinez-Mateo, Jesus; Elkouss, David; Martin, Vicente

2013-01-01

Quantum Key Distribution is carving its place among the tools used to secure communications. While a difficult technology, it enjoys benefits that set it apart from the rest, the most prominent is its provable security based on the laws of physics. QKD requires not only the mastering of signals at the quantum level, but also a classical processing to extract a secret-key from them. This postprocessing has been customarily studied in terms of the efficiency, a figure of merit that offers a biased view of the performance of real devices. Here we argue that it is the throughput the significant magnitude in practical QKD, specially in the case of high speed devices, where the differences are more marked, and give some examples contrasting the usual postprocessing schemes with new ones from modern coding theory. A good understanding of its implications is very important for the design of modern QKD devices. PMID:23546440

Model-Driven Safety Analysis of Closed-Loop Medical Systems

PubMed Central

Pajic, Miroslav; Mangharam, Rahul; Sokolsky, Oleg; Arney, David; Goldman, Julian; Lee, Insup

2013-01-01

In modern hospitals, patients are treated using a wide array of medical devices that are increasingly interacting with each other over the network, thus offering a perfect example of a cyber-physical system. We study the safety of a medical device system for the physiologic closed-loop control of drug infusion. The main contribution of the paper is the verification approach for the safety properties of closed-loop medical device systems. We demonstrate, using a case study, that the approach can be applied to a system of clinical importance. Our method combines simulation-based analysis of a detailed model of the system that contains continuous patient dynamics with model checking of a more abstract timed automata model. We show that the relationship between the two models preserves the crucial aspect of the timing behavior that ensures the conservativeness of the safety analysis. We also describe system design that can provide open-loop safety under network failure. PMID:24177176

Evaluating the decision accuracy and speed of clinical data visualizations.

PubMed

Pieczkiewicz, David S; Finkelstein, Stanley M

2010-01-01

Clinicians face an increasing volume of biomedical data. Assessing the efficacy of systems that enable accurate and timely clinical decision making merits corresponding attention. This paper discusses the multiple-reader multiple-case (MRMC) experimental design and linear mixed models as means of assessing and comparing decision accuracy and latency (time) for decision tasks in which clinician readers must interpret visual displays of data. These tools can assess and compare decision accuracy and latency (time). These experimental and statistical techniques, used extensively in radiology imaging studies, offer a number of practical and analytic advantages over more traditional quantitative methods such as percent-correct measurements and ANOVAs, and are recommended for their statistical efficiency and generalizability. An example analysis using readily available, free, and commercial statistical software is provided as an appendix. While these techniques are not appropriate for all evaluation questions, they can provide a valuable addition to the evaluative toolkit of medical informatics research.

Model-Driven Safety Analysis of Closed-Loop Medical Systems.

PubMed

Pajic, Miroslav; Mangharam, Rahul; Sokolsky, Oleg; Arney, David; Goldman, Julian; Lee, Insup

2012-10-26

In modern hospitals, patients are treated using a wide array of medical devices that are increasingly interacting with each other over the network, thus offering a perfect example of a cyber-physical system. We study the safety of a medical device system for the physiologic closed-loop control of drug infusion. The main contribution of the paper is the verification approach for the safety properties of closed-loop medical device systems. We demonstrate, using a case study, that the approach can be applied to a system of clinical importance. Our method combines simulation-based analysis of a detailed model of the system that contains continuous patient dynamics with model checking of a more abstract timed automata model. We show that the relationship between the two models preserves the crucial aspect of the timing behavior that ensures the conservativeness of the safety analysis. We also describe system design that can provide open-loop safety under network failure.

Focus: global currents in national histories of science: the "global turn" and the history of science in Latin America.

PubMed

McCook, Stuart

2013-12-01

The "global turn" in the history of science offers new ways to think about how to do national and regional histories of science, in this case the history of science in Latin America. For example, it questions structuralist and diffusionist models of the spread of science and shows the often active role that people in Latin America (and the rest of the Global South) played in the construction of "universal" scientific knowledge. It suggests that even national or regional histories of science must be situated in a global context; all too often, such histories have treated global processes as a distant backdrop. At the same time, historians need to pay constant attention to the role of power in the construction of scientific knowledge. Finally, this essay highlights a methodological tool for writing globally inflected histories of science: the method of "following".

Fostering engagement during termination: Applying attachment theory and research.

PubMed

Marmarosh, Cheri L

2017-03-01

Therapists often struggle to determine the most important things to focus on during termination. Reviewing the treatment, identifying plans for the future, summarizing positive gains, and saying goodbye receive the most attention. Despite our best intentions, termination can end up becoming intellectualized. Attachment theory and recent developments in neuroscience offer us a road map for facilitating endings that address client's underlying relational needs, direct us to foster engagement, and help us facilitate new relational experience that can be transformative for clients. We argue that endings in therapy activate client's and therapist's attachments and these endings trigger emotion regulating strategies that can elicit client's engagement or more defensiveness. The current paper will highlight through de-identified case examples how clients automatically respond termination and how therapists can foster rich relational experiences in the here-and-now that clients can take with them. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Integrating Parenting Support Within and Beyond the Pediatric Medical Home.

PubMed

Linton, Julie M; Stockton, Maria Paz; Andrade, Berta; Daniel, Stephanie

2018-01-01

Positive parenting programs, developmental support services, and evidence-based home visiting programs can effectively provide parenting support and improve health and developmental outcomes for at-risk children. Few models, however, have integrated referrals for on-site support and home visiting programs into the provision of routine pediatric care within a medical home. This article describes an innovative approach, through partnership with a community-based organization, to deliver on-site and home visiting support services for children and families within and beyond the medical home. Our model offers a system of on-site services, including parenting, behavior, and/or development support, with optional intensive home visiting services. Assessment included description of the population served, delineation of services provided, and qualitative identification of key themes of the impact of services, illustrated by case examples. This replicable model describes untapped potential of the pediatric medical home as a springboard to mitigate risk and optimize children's health and development.

Synthesis and chemistry of elemental 2D materials

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mannix, Andrew J.; Kiraly, Brian; Hersam, Mark C.

2017-01-25

2D materials have attracted considerable attention in the past decade for their superlative physical properties. These materials consist of atomically thin sheets exhibiting covalent in-plane bonding and weak interlayer and layer-substrate bonding. Following the example of graphene, most emerging 2D materials are derived from structures that can be isolated from bulk phases of layered materials, which form a limited library for new materials discovery. Entirely synthetic 2D materials provide access to a greater range of properties through the choice of constituent elements and substrates. Of particular interest are elemental 2D materials, because they provide the most chemically tractable case formore » synthetic exploration. In this Review, we explore the progress made in the synthesis and chemistry of synthetic elemental 2D materials, and offer perspectives and challenges for the future of this emerging field.« less

The effects of migrant remittances on population–environment dynamics in migrant origin areas: international migration, fertility, and consumption in highland Guatemala

PubMed Central

Lopez-Carr, David

2010-01-01

International migration impacts origin regions in many ways. As examples, remittances from distant migrants may alter consumption patterns within sending communities, while exposure to different cultural norms may alter other behaviors. This paper combines these insights to offer a unique lens on migration’s environmental impact. From an environmental perspective, we ask the following question: is the likely rise in consumption brought about by remittances counterbalanced by a reduction in fertility in migrant households following exposure to lower fertility cultures? Based on ethnographic case studies in two western highland Guatemalan communities, we argue that the near-term rise in consumption due to remittances is not counterbalanced by rapid decline in migrant household fertility. However, over time, the environmental cost of consumption may be mitigated at the community level through diffusion of contraception and family planning norms yielding lower family size. PMID:21258636

Shapes and features of the primordial bispectrum

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gong, Jinn-Ouk; Palma, Gonzalo A.; Sypsas, Spyros, E-mail: jinn-ouk.gong@apctp.org, E-mail: gpalmaquilod@ing.uchile.cl, E-mail: s.sypsas@gmail.com

If time-dependent disruptions from slow-roll occur during inflation, the correlation functions of the primordial curvature perturbation should have scale-dependent features, a case which is marginally supported from the cosmic microwave background (CMB) data. We offer a new approach to analyze the appearance of such features in the primordial bispectrum that yields new consistency relations and justifies the search of oscillating patterns modulated by orthogonal and local templates. Under the assumption of sharp features, we find that the cubic couplings of the curvature perturbation can be expressed in terms of the bispectrum in two specific momentum configurations, for example local andmore » equilateral. This allows us to derive consistency relations among different bispectrum shapes, which in principle could be tested in future CMB surveys. Furthermore, based on the form of the consistency relations, we construct new two-parameter templates for features that include all the known shapes.« less

Cultural unconscious in research: integrating multicultural and depth paradigms in qualitative research.

PubMed

Yakushko, Oksana; Miles, Pekti; Rajan, Indhushree; Bujko, Biljana; Thomas, Douglas

2016-11-01

Culturally focused research has gained momentum in many disciplines, including psychology. However, much of this research fails to pay attention to the unconscious dynamics that underlie the study of culture and culturally influenced human beings. Such dynamics may be especially significant when issues of marginalization and oppression are present. Therefore, this paper seeks to contribute a framework for understanding cultural dynamics, especially unconscious cultural dynamics, within depth psychological qualitative research influenced by Jungian and post-Jungian scholarship. Inquiry that is approached with a commitment to making the unconscious conscious seeks to empower and liberate not only the subject/object studied but also the researchers themselves. Following a brief review of multiculturalism in the context of analytically informed psychology, this paper offers several case examples that focus on researchers' integration of awareness of the cultural unconscious in their study of cultural beings and topics. © 2016, The Society of Analytical Psychology.

How much separation for LC-MS/MS quantitative bioanalysis of drugs and metabolites?

PubMed

Tan, Aimin; Fanaras, John C

2018-05-01

LC-MS/MS has been the dominant analytical technology for quantitative bioanalysis of drugs and metabolites for more than two decades. Despite this, a very fundamental question like how much separation is required for LC-MS/MS quantitative bioanalysis of drugs and metabolites has not been adequately addressed. Some think that no or only very limited separation is necessary thanks to the unparalleled selectivity offered by tandem mass spectrometry. Others think that the more separation, the better, because of the potential detrimental impact of matrix effect (ion suppression or enhancement). Still others just use a rule-of-thumb approach by keeping the adjusted retention/capacity factor always between 2 and 5. The purpose of this article is to address this fundamental question through rational thinking together with various real case examples drawn from regulated bioanalytical laboratories. Copyright © 2018 Elsevier B.V. All rights reserved.

Transformism in Alberta: The Environmental Political Economy of the Bituminous Sands

NASA Astrophysics Data System (ADS)

Katz-Rosene, Ryan

This thesis attempts to help establish environmental political economy as a viable academic field while providing an example of work in the discipline. It offers an analysis of societal processes resulting in the co-optation and/or neutralization of critical environmentalist ideas. Using Alberta's bituminous sands as a case study, and a Gramsci-influenced eco-Marxist theory as a foundation, the thesis argues that the term 'environmental transformism' (inspired by the Gramscian term trasformismo) is helpful in describing and framing such processes. Accordingly, the ensuing chapters provide an analysis of why environmental transformism is happening in Alberta, and demonstrate how this mechanism works at protecting the status quo from threatening ideologies, thereby consolidating neoliberal capitalism. A concluding argument discusses the inherent dangers posed to society by the transformism of certain environmental subjectivities. The thesis begins by introducing the contentious social and environmental issues surrounding the development of the bituminous sands.

Formate production through carbon dioxide hydrogenation with recombinant whole cell biocatalysts.

PubMed

Alissandratos, Apostolos; Kim, Hye-Kyung; Easton, Christopher J

2014-07-01

The biological conversion of CO2 and H2 into formate offers a sustainable route to a valuable commodity chemical through CO2 fixation, and a chemical form of hydrogen fuel storage. Here we report the first example of CO2 hydrogenation utilising engineered whole-cell biocatalysts. Escherichia coli JM109(DE3) cells transformed for overexpression of either native formate dehydrogenase (FDH), the FDH from Clostridium carboxidivorans, or genes from Pyrococcus furiosus and Methanobacterium thermoformicicum predicted to express FDH based on their similarity to known FDH genes were all able to produce levels of formate well above the background, when presented with H2 and CO2, the latter in the form of bicarbonate. In the case of the FDH from P. furiosus the yield was highest, reaching more than 1 g L(-1)h(-1) when a hydrogen-sparging reactor design was used. Copyright © 2014 Elsevier Ltd. All rights reserved.

A Computational and Experimental Study of Slit Resonators

NASA Technical Reports Server (NTRS)

Tam, C. K. W.; Ju, H.; Jones, M. G.; Watson, W. R.; Parrott, T. L.

2003-01-01

Computational and experimental studies are carried out to offer validation of the results obtained from direct numerical simulation (DNS) of the flow and acoustic fields of slit resonators. The test cases include slits with 90-degree corners and slits with 45-degree bevel angle housed inside an acoustic impedance tube. Three slit widths are used. Six frequencies from 0.5 to 3.0 kHz are chosen. Good agreement is found between computed and measured reflection factors. In addition, incident sound waves having white noise spectrum and a prescribed pseudo-random noise spectrum are used in subsequent series of tests. The computed broadband results are again found to agree well with experimental data. It is believed the present results provide strong support that DNS can eventually be a useful and accurate prediction tool for liner aeroacoustics. The usage of DNS as a design tool is discussed and illustrated by a simple example.

[Archaeology and criminology--Strengths and weaknesses of interdisciplinary cooperation].

PubMed

Bachhiesl, Christian

2015-01-01

Interdisciplinary cooperation of archaeology and criminology is often focussed on the scientific methods applied in both fields of knowledge. In combination with the humanistic methods traditionally used in archaeology, the finding of facts can be enormously increased and the subsequent hermeneutic deduction of human behaviour in the past can take place on a more solid basis. Thus, interdisciplinary cooperation offers direct and indirect advantages. But it can also cause epistemological problems, if the weaknesses and limits of one method are to be corrected by applying methods used in other disciplines. This may result in the application of methods unsuitable for the problem to be investigated so that, in a way, the methodological and epistemological weaknesses of two disciplines potentiate each other. An example of this effect is the quantification of qualia. These epistemological reflections are compared with the interdisciplinary approach using the concrete case of the "Eulau Crime Scene".

Supervised Learning for Dynamical System Learning.

PubMed

Hefny, Ahmed; Downey, Carlton; Gordon, Geoffrey J

2015-01-01

Recently there has been substantial interest in spectral methods for learning dynamical systems. These methods are popular since they often offer a good tradeoff between computational and statistical efficiency. Unfortunately, they can be difficult to use and extend in practice: e.g., they can make it difficult to incorporate prior information such as sparsity or structure. To address this problem, we present a new view of dynamical system learning: we show how to learn dynamical systems by solving a sequence of ordinary supervised learning problems, thereby allowing users to incorporate prior knowledge via standard techniques such as L 1 regularization. Many existing spectral methods are special cases of this new framework, using linear regression as the supervised learner. We demonstrate the effectiveness of our framework by showing examples where nonlinear regression or lasso let us learn better state representations than plain linear regression does; the correctness of these instances follows directly from our general analysis.

Organic Solar Cells beyond One Pair of Donor-Acceptor: Ternary Blends and More.

PubMed

Yang, Liqiang; Yan, Liang; You, Wei

2013-06-06

Ternary solar cells enjoy both an increased light absorption width, and an easy fabrication process associated with their simple structures. Significant progress has been made for such solar cells with demonstrated efficiencies over 7%; however, their fundamental working principles are still under investigation. This Perspective is intended to offer our insights on the three major governing mechanisms in these intriguing ternary solar cells: charge transfer, energy transfer, and parallel-linkage. Through careful analysis of exemplary cases, we summarize the advantages and limitations of these three major mechanisms and suggest future research directions. For example, incorporating additional singlet fission or upconversion materials into the energy transfer dominant ternary solar cells has the potential to break the theoretical efficiency limit in single junction organic solar cells. Clearly, a feedback loop between fundamental understanding and materials selection is in urgent need to accelerate the efficiency improvement of these ternary solar cells.

Spatiotemporal multivariate mixture models for Bayesian model selection in disease mapping.

PubMed

Lawson, A B; Carroll, R; Faes, C; Kirby, R S; Aregay, M; Watjou, K

2017-12-01

It is often the case that researchers wish to simultaneously explore the behavior of and estimate overall risk for multiple, related diseases with varying rarity while accounting for potential spatial and/or temporal correlation. In this paper, we propose a flexible class of multivariate spatio-temporal mixture models to fill this role. Further, these models offer flexibility with the potential for model selection as well as the ability to accommodate lifestyle, socio-economic, and physical environmental variables with spatial, temporal, or both structures. Here, we explore the capability of this approach via a large scale simulation study and examine a motivating data example involving three cancers in South Carolina. The results which are focused on four model variants suggest that all models possess the ability to recover simulation ground truth and display improved model fit over two baseline Knorr-Held spatio-temporal interaction model variants in a real data application.

Continuity and change in local immigrant policies in times of austerity.

PubMed

Schiller, Maria; Hackett, Sarah

2018-01-01

European cities are increasingly being recognised for the role they play in devising and implementing their own migration, integration and diversity policies. Yet very little is known about the local dimension of immigrant policymaking in crisis contexts. This introductory piece offers a rationale for analysing city-level immigrant policies in times of crisis and the salience of using crisis as a metaphor for the state of things, and outlines key scholarly works, debates, concepts and theories. It provides a range of historical and contemporary examples and considerations, and introduces an empirical city case study that is published as part of this mini-symposium. It argues that a crisis lens leads to a systematic understanding of local-level immigrant policymaking in recent and contemporary Western Europe. The mini-symposium's focus and findings should be relevant to both on-going academic and policy debates.

Unexpected Outcomes of Thai Cassava Trade: A Case of Global Complexity and Local Unsustainability

PubMed Central

CURRAN, SARA R.; COOKE, ABIGAIL M.

2014-01-01

Tracing the Thai cassava (Manihot esculenta) trade network, between 1960 and 2000, offers a compelling example of global complexity at work. The emergence of Thailand’s dominance of world export markets caught the world by surprise. The opening up of a European market for cassava was supposed to be met by Brazilian and Indonesian producers. Instead, Thailand took over the market by 1975. Several factors facilitated this emergence including: entrepreneurial diasporic networks of Thai-Chinese traders, local political economy conditions in both Europe and Thailand, and ecological conditions in Thailand. These same factors also shaped the subsequent timing of the closing of the European market, the emergence of a new industry association, the creation of new cassava products, and the expansion to other markets. Furthermore, the dynamic nature of cassava market yielded equivocal outcomes for both Europe and Thai farmers. PMID:25328444

A Pilot Study of Mindfulness Meditation for Pediatric Chronic Pain

PubMed Central

Waelde, Lynn C.; Feinstein, Amanda B.; Bhandari, Rashmi; Griffin, Anya; Yoon, Isabel A.; Golianu, Brenda

2017-01-01

Despite advances in psychological interventions for pediatric chronic pain, there has been little research examining mindfulness meditation for these conditions. This study presents data from a pilot clinical trial of a six-week manualized mindfulness meditation intervention offered to 20 adolescents aged 13–17 years. Measures of pain intensity, functional disability, depression and parent worry about their child’s pain were obtained at baseline and post-treatment. Results indicated no significant changes in pain or depression, however functional disability and frequency of pain functioning complaints improved with small effect sizes. Parents’ worry about child’s pain significantly decreased with a large effect size. Participants rated intervention components positively and most teens suggested that the number of sessions be increased. Three case examples illustrate mindfulness meditation effects and precautions. Mindfulness meditation shows promise as a feasible and acceptable intervention for youth with chronic pain. Future research should optimize intervention components and determine treatment efficacy. PMID:28445406

Consumer Education in Any Class

ERIC Educational Resources Information Center

Wingo, Rosetta F.

1977-01-01

Examples are offered of how the classroom teacher can blend consumer education into typewriting, business English, business math, and other classes by intentionally focusing on principles and concepts or by including it incidentally when the opportunity arises. (TA)

A methodology to evaluate unplanned proposed transportation projects.

DOT National Transportation Integrated Search

2008-01-01

The Virginia Department of Transportation may be asked to consider proposed transportation projects that have not originated within the transportation planning process. Examples include offers by the private sector to build infrastructure in exchange...

Toward an Organic Chemist's Periodic Table.

ERIC Educational Resources Information Center

Hall, H. K., Jr.

1980-01-01

An analogy between electron transfer reactions of the elements and those of organic molecules is offered. Examples of organic electron transfer reactions are presented. The rationale of constructing an organic chemists' periodic table is also discussed. (HM)

Is Science Biased Toward Natural?

EPA Science Inventory

Having widely available, accurate, understandable, and unbiased scientific information is central to the successful resolution of the typically contentious, divisive, and litigious natural resource policy issue. Three examples are offered to illustrate how science is often misus...

Eldercare at Home: Choosing a Nursing Home

MedlinePlus

... a stay of two to four weeks for physical therapy. An example of a long-term stay would ... by a qualified pharmacist? Does the home offer physical therapy and other rehabilitative services? Are interesting activities scheduled? ...

Catalysis of Photochemical Reactions.

ERIC Educational Resources Information Center

Albini, A.

1986-01-01

Offers a classification system of catalytic effects in photochemical reactions, contrasting characteristic properties of photochemical and thermal reactions. Discusses catalysis and sensitization, examples of catalyzed reactions of excepted states, complexing ground state substrates, and catalysis of primary photoproducts. (JM)

Making Connections.

ERIC Educational Resources Information Center

Garbe, Edward

1998-01-01

Discusses enhancing a college's competitive position by offering technological capabilities to its students, including the planning process and wiring installation issues to be considered. Highlights two examples concerning building the wiring infrastructure to support multipurpose, technology-rich learning environments. (GR)

Ultrasonic material property determinations

NASA Technical Reports Server (NTRS)

Serabian, S.

1986-01-01

The use and potential offered by ultrasonic velocity and attenuation measurements to determine and/or monitor material properties is explored. The basis for such unique measurements along with examples of materials from a variety of industries are presented.

Examples of Strategic Planning at Several Levels.

ERIC Educational Resources Information Center

Pailthorp, Keith G.

1986-01-01

Three different approaches to environmental scanning for strategic planning are offered. Long-range planning in the San Francisco Community College District, the University of Nevada, Reno, and the California Postsecondary Education Commission are described. (MLW)

Visual Thinking, Algebraic Thinking, and a Full Unit-Circle Diagram.

ERIC Educational Resources Information Center

Shear, Jonathan

1985-01-01

The study of trigonometric functions in terms of the unit circle offer an example of how students can learn algebraic relations and operations while using visually oriented thinking. Illustrations are included. (MNS)

OMNY PIN—A versatile sample holder for tomographic measurements at room and cryogenic temperatures

NASA Astrophysics Data System (ADS)

Holler, M.; Raabe, J.; Wepf, R.; Shahmoradian, S. H.; Diaz, A.; Sarafimov, B.; Lachat, T.; Walther, H.; Vitins, M.

2017-11-01

Nowadays ptychographic tomography in the hard x-ray regime, i.e., at energies above about 2 keV, is a well-established measurement technique. At the Paul Scherrer Institut, currently two instruments are available: one is measuring at room temperature and atmospheric pressure, and the other, the so-called OMNY (tOMography Nano crYo) instrument, is operating at ultra-high vacuum and offering cryogenic sample temperatures down to 10 K. In this manuscript, we present the sample mounts that were developed for these instruments. Aside from excellent mechanical stability and thermal conductivity, they also offer highly reproducible mounting. Various types were developed for different kinds of samples and are presented in detail, including examples of how specimens can be mounted on these holders. We also show the first hard x-ray ptychographic tomography measurements of high-pressure frozen biological samples, in the present case Chlamydomonas cells, the related sample pins and preparation steps. For completeness, we present accessories such as transportation containers for both room temperature and cryogenic samples and a gripper mechanism for automatic sample changing. The sample mounts are not limited to x-ray tomography or hard x-ray energies, and we believe that they can be very useful for other instrumentation projects.

‘In the Moment’: An Analysis of Facilitator Impact During a Quality Improvement Process

PubMed Central

Shaw, Erik; Looney, Anna; Chase, Sabrina; Navalekar, Rohini; Stello, Brian; Lontok, Oliver; Crabtree, Benjamin

2010-01-01

Facilitators frequently act ‘in the moment’ – deciding if, when and how to intervene into group process discussions. This paper offers a unique look at how facilitators impacted eleven primary care teams engaged in a 12-week quality improvement (QI) process. Participating in a federally funded QI trial, primary care practices in New Jersey and Pennsylvania formed practice-based teams comprised of physicians, nurses, administrative staff, and patients. External facilitators met with each team to help them identify and implement changes aimed at improving the organization, work relationships, office functions, and patient care. Audio-recordings of the meetings and descriptive field notes were collected. These qualitative data provided information on how facilitators acted ‘in the moment’ and how their interventions impacted group processes over time. Our findings reveal that facilitators impacted groups in multiple ways throughout the QI process, rather than through a linear progression of stages or events. We present five case examples that show what acting ‘in the moment’ looked like during the QI meetings and how these facilitator actions/interventions impacted the primary care teams. These accounts provide practical lessons learned and insights into effective facilitation that may encourage others in their own facilitation work and offer beneficial strategies to facilitators in other contexts. PMID:22557936

A Robust Ordering Strategy for Retailers Facing a Free Shipping Option

PubMed Central

Meng, Qing-chun; Wan, Xiao-le; Rong, Xiao-xia

2015-01-01

Free shipping with conditions has become one of the most effective marketing tools available. An increasing number of companies, especially e-businesses, prefer to offer free shipping with some predetermined condition, such as a minimum purchase amount by the customer. However, in practice, the demands of buyers are uncertain; they are often affected by many factors, such as the weather and season. We begin by modeling the centralized ordering problem in which the supplier offers a free shipping service and retailers face stochastic demands. As these random data are considered, only partial information such as the known mean, support, and deviation is needed. The model is then analyzed via a robust optimization method, and the two types of equivalent sets of uncertainty constraints that are obtained provide good mathematical properties with consideration of the robustness of solutions. Subsequently, a numerical example is used to compare the results achieved from a robust optimization method and the linear decision rules. Additionally, the robustness of the optimal solution is discussed, as it is affected by the minimum quantity parameters. The increasing cost-threshold relationship is divided into three periods. In addition, the case study shows that the proposed method achieves better stability as well as computational complexity. PMID:25993533

Acute movement disorders in the medical setting.

PubMed

Zawar, Ifrah; Caro, Mario A; Feldman, Lara; Jimenez, Xavier F

2016-07-01

Objective Psychosomatic medicine psychiatrists are often tasked with the evaluation and treatment of complex neuropsychiatric states which may be motoric in phenotype. Little energy has been dedicated to understanding acute movement disorders in the hospital environment. Method Recognizing the importance of frontal-subcortical (corticostriatothalamocortical) circuitry and basal ganglia structures, we present a case series of acute movement disorder phenotypes resulting from underlying medical conditions, commonly-administered medications, or the interaction of both. We organize these scenarios into neurodegenerative disorders, primary psychiatric disorders, neuroinflammation, and polypharmacy, demonstrating a clinical example of each followed by background references on a variety of clinical states and medications contributing to acute movement disorders. In addition, we offer visual illustration of implicated neurocircuitry as well as proposed neurotransmitter imbalances involving glutamate, gamma aminobutyric acid, and dopamine. Furthermore, we review the various clinical syndromes and medications involved in the development of acute movement disorders. Results Acute movement disorder's involve complex interactions between frontal-subcortical circuits and acute events. Given the complexity of interactions, psychopharmacological considerations become critical, as some treatments may alleviate acute movement disorders while others will exacerbate them. Conclusion Integrating underlying medical conditions and acutely administered (or discontinued) pharmacological agents offers an interactional, neuromedical approach to acute movement disorders that is critical to the work of psychosomatic medicine.

Poroelastic Modeling as a Proof of Concept for Modular Representation of Coupled Geophysical Processes

NASA Astrophysics Data System (ADS)

Walker, R. L., II; Knepley, M.; Aminzadeh, F.

2017-12-01

We seek to use the tools provided by the Portable, Extensible Toolkit for Scientific Computation (PETSc) to represent a multiphysics problem in a form that decouples the element definition from the fully coupled equation through the use of pointwise functions that imitate the strong form of the governing equation. This allows allows individual physical processes to be expressed as independent kernels that may be then coupled with the existing finite element framework, PyLith, and capitalizes upon the flexibility offered by the solver, data management, and time stepping algorithms offered by PETSc. To demonstrate a characteristic example of coupled geophysical simulation devised in this manner, we present a model of a synthetic poroelastic environment, with and without the consideration of inertial effects, with fluid initially represented as a single phase. Matrix displacement and fluid pressure serve as the desired unknowns, with the option for various model parameters represented as dependent variables of the central unknowns. While independent of PyLith, this model also serves to showcase the adaptability of physics kernels for synthetic forward modeling. In addition, we seek to expand the base case to demonstrate the impact of modeling fluid as single phase compressible versus a single incompressible phase. As a goal, we also seek to include multiphase fluid modeling, as well as capillary effects.

SPATE applications in North America - Report on U.S. SPATE users group

NASA Astrophysics Data System (ADS)

Oliver, David E.; Jaeger, Paul

1987-04-01

This paper offers an overview of SPATE activities in the U.S. Examples of industrial applications range from small aero-engine turbine blades tested at excitation frequencies in excess of 20 kHz to composite pressure vessels loaded at 0.5 Hz. Particular attention is given to some activities of the University of Wisconsin (Madison) and Virginia Polytechnic Institute and State University, both of which are offering some pioneering work in SPATE applications research.

HIFI-C: a robust and fast method for determining NMR couplings from adaptive 3D to 2D projections.

PubMed

Cornilescu, Gabriel; Bahrami, Arash; Tonelli, Marco; Markley, John L; Eghbalnia, Hamid R

2007-08-01

We describe a novel method for the robust, rapid, and reliable determination of J couplings in multi-dimensional NMR coupling data, including small couplings from larger proteins. The method, "High-resolution Iterative Frequency Identification of Couplings" (HIFI-C) is an extension of the adaptive and intelligent data collection approach introduced earlier in HIFI-NMR. HIFI-C collects one or more optimally tilted two-dimensional (2D) planes of a 3D experiment, identifies peaks, and determines couplings with high resolution and precision. The HIFI-C approach, demonstrated here for the 3D quantitative J method, offers vital features that advance the goal of rapid and robust collection of NMR coupling data. (1) Tilted plane residual dipolar couplings (RDC) data are collected adaptively in order to offer an intelligent trade off between data collection time and accuracy. (2) Data from independent planes can provide a statistical measure of reliability for each measured coupling. (3) Fast data collection enables measurements in cases where sample stability is a limiting factor (for example in the presence of an orienting medium required for residual dipolar coupling measurements). (4) For samples that are stable, or in experiments involving relatively stronger couplings, robust data collection enables more reliable determinations of couplings in shorter time, particularly for larger biomolecules. As a proof of principle, we have applied the HIFI-C approach to the 3D quantitative J experiment to determine N-C' RDC values for three proteins ranging from 56 to 159 residues (including a homodimer with 111 residues in each subunit). A number of factors influence the robustness and speed of data collection. These factors include the size of the protein, the experimental set up, and the coupling being measured, among others. To exhibit a lower bound on robustness and the potential for time saving, the measurement of dipolar couplings for the N-C' vector represents a realistic "worst case analysis". These couplings are among the smallest currently measured, and their determination in both isotropic and anisotropic media demands the highest measurement precision. The new approach yielded excellent quantitative agreement with values determined independently by the conventional 3D quantitative J NMR method (in cases where sample stability in oriented media permitted these measurements) but with a factor of 2-5 in time savings. The statistical measure of reliability, measuring the quality of each RDC value, offers valuable adjunct information even in cases where modest time savings may be realized.

The effect of verbal context on olfactory neural responses.

PubMed

Bensafi, Moustafa; Croy, Ilona; Phillips, Nicola; Rouby, Catherine; Sezille, Caroline; Gerber, Johannes; Small, Dana M; Hummel, Thomas

2014-03-01

Odor names refer usually to "source" object categories. For example, the smell of rose is often described with its source category (flower). However, linguistic studies suggest that odors can also be named with labels referring to categories of "practices". This is the case when rose odor is described with a verbal label referring to its use in fragrance practices ("body lotion," cosmetic for example). It remains unknown whether naming an odor by its practice category influences olfactory neural responses differently than that observed when named with its source category. The aim of this study was to investigate this question. To this end, functional MRI was used in a within-subjects design comparing brain responses to four different odors (peach, chocolate, linden blossom, and rose) under two conditions whereby smells were described either (1) with their source category label (food and flower) or (2) with a practice category label (body lotion). Both types of labels induced activations in secondary olfactory areas (orbitofrontal cortex), whereas only the source label condition induced activation in the cingulate cortex and the insula. In summary, our findings offer a new look at olfactory perception by indicating differential brain responses depending on whether odors are named according to their source or practice category. Copyright © 2012 Wiley Periodicals, Inc.

Two-Stage Residual Inclusion Estimation in Health Services Research and Health Economics.

PubMed

Terza, Joseph V

2018-06-01

Empirical analyses in health services research and health economics often require implementation of nonlinear models whose regressors include one or more endogenous variables-regressors that are correlated with the unobserved random component of the model. In such cases, implementation of conventional regression methods that ignore endogeneity will likely produce results that are biased and not causally interpretable. Terza et al. (2008) discuss a relatively simple estimation method that avoids endogeneity bias and is applicable in a wide variety of nonlinear regression contexts. They call this method two-stage residual inclusion (2SRI). In the present paper, I offer a 2SRI how-to guide for practitioners and a step-by-step protocol that can be implemented with any of the popular statistical or econometric software packages. We introduce the protocol and its Stata implementation in the context of a real data example. Implementation of 2SRI for a very broad class of nonlinear models is then discussed. Additional examples are given. We analyze cigarette smoking as a determinant of infant birthweight using data from Mullahy (1997). It is hoped that the discussion will serve as a practical guide to implementation of the 2SRI protocol for applied researchers. © Health Research and Educational Trust.

Retailer Stackelberg game in a supply chain with pricing and service decisions and simple price discount contract.

PubMed

Sadjadi, Seyed Jafar; Asadi, Hashem; Sadeghian, Ramin; Sahebi, Hadi

2018-01-01

This paper studies the Retailer Stackelberg game in a supply chain consisting of two manufacturers and one retailer where they compete simultaneously under three factors including price, service and simple price discount contract. It is assumed that the second manufacturer provides service directly to his customers, and the retailer provides service for the first product's customers, while the retailer buys the first product under price discount from the first manufacturer. The analysis of the optimal equilibrium solutions and the results of the numerical examples show that if a manufacturer chooses the appropriate range of discount rate, he will gain more profit than when there is no discount given to the retailer. This situation can be considered as an effective tool for the coordination of the first manufacturer and the retailer to offer discount by manufacturer and to provide the service by the retailer. We obtain equilibrium solution of Retailer Stackelberg game and analyze the numerical examples under two cases: a) the manufacturers sell their products to the retailer without price discount contract. b) The first manufacturer sells his products to the retailer with the simple price discount contract. The preliminary results show that the service and the price discount contract can improve the performance of supply chain.

Human research ethics committees in technical universities.

PubMed

Koepsell, David; Brinkman, Willem-Paul; Pont, Sylvia

2014-07-01

Human research ethics has developed in both theory and practice mostly from experiences in medical research. Human participants, however, are used in a much broader range of research than ethics committees oversee, including both basic and applied research at technical universities. Although mandated in the United States, the United Kingdom, Canada, and Australia, non-medical research involving humans need not receive ethics review in much of Europe, Asia, Latin America, and Africa. Our survey of the top 50 technical universities in the world shows that, where not specifically mandated by law, most technical universities do not employ ethics committees to review human studies. As the domains of basic and applied sciences expand, ethics committees are increasingly needed to guide and oversee all such research regardless of legal requirements. We offer as examples, from our experience as an ethics committee in a major European technical university, ways in which such a committee provides needed services and can help ensure more ethical studies involving humans outside the standard medical context. We provide some arguments for creating such committees, and in our supplemental article, we provide specific examples of cases and concerns that may confront technical, engineering, and design research, as well as outline the general framework we have used in creating our committee. © The Author(s) 2014.

Beyond the feminisation of poverty: gender-aware poverty reduction.

PubMed

Lockwood, M; Baden, S

1995-09-01

There must be an awareness of gender issues in poverty reduction programs. For example, program efforts that direct aid to the promotion of labor intensive employment options disregard women's already overburdened work regime. Public expenditures to benefit the poor, such as primary education or reformed agricultural extension, may be based on the assumption that men and women will benefit equally, yet there is often gender bias in the delivery of services. One recommendation is to target female headed households in budget-constrained anti-poverty programs. One of the few examples of such programs provides urban female household heads in Chile with employment training, housing, health care, child care, and legal aid services. Causes of female headship vary, and a simple correlation with poverty is not always the case. Well-intentioned women-in-development credit programs in Ghana and Bangladesh have been "hijacked" by men. Programs to address gender discrimination only among the poor may overlook other oppressed women. In India gender discrimination is often greatest among women in wealthy households. Programs must offer more than economic resources, they must help women stretch traditional gender boundaries and obtain skills such as literacy or financial management. They must help women organize collectively to protest injustices and achieve institutional reforms.

Retailer Stackelberg game in a supply chain with pricing and service decisions and simple price discount contract

PubMed Central

Sadjadi, Seyed Jafar; Sadeghian, Ramin; Sahebi, Hadi

2018-01-01

This paper studies the Retailer Stackelberg game in a supply chain consisting of two manufacturers and one retailer where they compete simultaneously under three factors including price, service and simple price discount contract. It is assumed that the second manufacturer provides service directly to his customers, and the retailer provides service for the first product’s customers, while the retailer buys the first product under price discount from the first manufacturer. The analysis of the optimal equilibrium solutions and the results of the numerical examples show that if a manufacturer chooses the appropriate range of discount rate, he will gain more profit than when there is no discount given to the retailer. This situation can be considered as an effective tool for the coordination of the first manufacturer and the retailer to offer discount by manufacturer and to provide the service by the retailer. We obtain equilibrium solution of Retailer Stackelberg game and analyze the numerical examples under two cases: a) the manufacturers sell their products to the retailer without price discount contract. b) The first manufacturer sells his products to the retailer with the simple price discount contract. The preliminary results show that the service and the price discount contract can improve the performance of supply chain. PMID:29649315

Understanding molecular structure from molecular mechanics.

PubMed

Allinger, Norman L

2011-04-01

Molecular mechanics gives us a well known model of molecular structure. It is less widely recognized that valence bond theory gives us structures which offer a direct interpretation of molecular mechanics formulations and parameters. The electronic effects well-known in physical organic chemistry can be directly interpreted in terms of valence bond structures, and hence quantitatively calculated and understood. The basic theory is outlined in this paper, and examples of the effects, and their interpretation in illustrative examples is presented.

Using client feedback in psychotherapy from an interpersonal process perspective.

PubMed

Reese, Robert J; Slone, Norah C; Miserocchi, Kristin M

2013-09-01

The process of monitoring treatment outcome, also known as "client feedback," is increasingly becoming a recommended practice for psychotherapy. One concern, however, is how to integrate such a process into the work that psychotherapists typically do. Three clinical examples are presented, illustrating how a client feedback system can be used in conjunction with a specific theoretical framework, interpersonal process therapy (Teyber, 2006). The examples highlight that client feedback not only can be of minimal disruption to the psychotherapy process, but may also offer the potential to augment a clinician's approach to helping. Theoretical and research support are provided for each example. 2013 APA, all rights reserved

Physics in Literature

NASA Astrophysics Data System (ADS)

Manos, Harry

2014-01-01

Physics offers a cross-discipline perspective to understanding other subjects. The purpose of this paper is to provide examples of physics in literature that physics and astronomy teachers can use to give students an indication of the relevance of science as depicted in the humanities. It is not possible to cite the thousands of examples available. I have tried to select authors whom students would be reading in high school and in college undergraduate English classes: in particular Joseph Conrad, Samuel Taylor Coleridge, William Shakespeare, H. G. Wells, Fyodor Dostoevsky, Norman Mailer, and an author currently in vogue, Dan Brown. I am sure many reading this article will come up with their own examples.

Interagency Cooperation for Irregular Warfare at the Combatant Command

DTIC Science & Technology

2009-01-01

Directorate, and the USSOCOM Interagency Task Force ( IATF ) offer examples of JIACGs coping with the issues of IW. Each organization possesses strengths...46 USSOCOM IATF History...Force for Irregular Warfare ( IATF IW).33 EUCOM conducts interagency

Principled 'Bastard' Leadership? A Rejoinder to Gold, Evans, Earley, Halpin and Collarbone.

ERIC Educational Resources Information Center

Wright, Nigel

2003-01-01

Rejoinder to "Principled Principals" article (EA0000000). Asserts, for example, that offering second-order values such as questioning as evidence of principled leadership does not obviate "bastard leadership." (Contains 10 references.) (PKP)

Corporate Advertisements and Environmental Futures: An Educational Odyssey.

ERIC Educational Resources Information Center

Thomashow, Mitchell

1988-01-01

Analyzes advertisements as vision, myth, and mirror. Provides an interpretive technique that can be used as a curriculum for studying issues advertisements. Offers eight advertisements as examples and provides an analysis and critique of each. (MVL)

Office Sexism--Women Against Themselves

ERIC Educational Resources Information Center

Tillar, Darrel Long; Maidment, Robert

1978-01-01

The existence of discrimination toward women managers by other women is examined briefly, with examples of attitudes and office situations cited. Suggestions are offered for an effective manager to minimize the potential nonproductivity caused by women against themselves. (LBH)

Power and Efficiency.

ERIC Educational Resources Information Center

Boyd, James N.

1991-01-01

Presents a mathematical problem that, when examined and generalized, develops the relationships between power and efficiency in energy transfer. Offers four examples of simple electrical and mechanical systems to illustrate the principle that maximum power occurs at 50 percent efficiency. (MDH)

Change Strategies Used by a Proprietary School: The Dale Carnegie Organization.

ERIC Educational Resources Information Center

Mackey, Paul J.

1983-01-01

Discusses recent developments regarding proprietary schools: recognition by accrediting associations, increased federal aid, and increased need for the specific training offered by these schools. Uses the Dale Carnegie organization as an example. (JOW)

Creative Visualization Activities.

ERIC Educational Resources Information Center

Fugitt, Eva D.

1986-01-01

Presents a series of classroom exercises and activities that stimulate children's creativity through the use of visualization. Discusses procedures for guided imagery and offers some examples of "trips" to imaginary places. Proposes visualization as a warm-up exercise before art lessons. (DR)

Enhanced reproducibility of SADI web service workflows with Galaxy and Docker.

PubMed

Aranguren, Mikel Egaña; Wilkinson, Mark D

2015-01-01

Semantic Web technologies have been widely applied in the life sciences, for example by data providers such as OpenLifeData and through web services frameworks such as SADI. The recently reported OpenLifeData2SADI project offers access to the vast OpenLifeData data store through SADI services. This article describes how to merge data retrieved from OpenLifeData2SADI with other SADI services using the Galaxy bioinformatics analysis platform, thus making this semantic data more amenable to complex analyses. This is demonstrated using a working example, which is made distributable and reproducible through a Docker image that includes SADI tools, along with the data and workflows that constitute the demonstration. The combination of Galaxy and Docker offers a solution for faithfully reproducing and sharing complex data retrieval and analysis workflows based on the SADI Semantic web service design patterns.

Risk-based requirements management framework with applications to assurance cases

NASA Astrophysics Data System (ADS)

Feng, D.; Eyster, C.

The current regulatory approach for assuring device safety primarily focuses on compliance with prescriptive safety regulations and relevant safety standards. This approach, however, does not always lead to a safe system design even though safety regulations and standards have been met. In the medical device industry, several high profile recalls involving infusion pumps have prompted the regulatory agency to reconsider how device safety should be managed, reviewed and approved. An assurance case has been cited as a promising tool to address this growing concern. Assurance cases have been used in safety-critical systems for some time. Most assurance cases, if not all, in literature today are developed in an ad hoc fashion, independent from risk management and requirement development. An assurance case is a resource-intensive endeavor that requires additional effort and documentation from equipment manufacturers. Without a well-organized requirements infrastructure in place, such “ additional effort” can be substantial, to the point where the cost of adoption outweighs the benefit of adoption. In this paper, the authors present a Risk-Based Requirements and Assurance Management (RBRAM) methodology. The RBRAM is an elaborate framework that combines Risk-Based Requirements Management (RBRM) with assurance case methods. Such an integrated framework can help manufacturers leverage an existing risk management to present a comprehensive assurance case with minimal additional effort while providing a supplementary means to reexamine the integrity of the system design in terms of the mission objective. Although the example used is from the medical industry, the authors believe that the RBRAM methodology underlines the fundamental principle of risk management, and offers a simple, yet effective framework applicable to aerospace industry, perhaps, to any industry.

Non-Abelian clouds around Reissner-Nordström black holes: The existence line

NASA Astrophysics Data System (ADS)

Radu, Eugen; Tchrakian, D. H.; Yang, Yisong

2016-06-01

A known feature of electrically charged Reissner-Nordström-anti-de Sitter planar black holes is that they can become unstable when considered as solutions of Einstein-Yang-Mills theory. The mechanism for this is that the linearized Yang-Mills equations in the background of the Reissner-Nordström (RN) black holes possess a normalizable zero mode, resulting in non-Abelian (nA) magnetic clouds near the horizon. In this work we show that the same pattern may occur also for asymptotically flat RN black holes. Different from the anti-de Sitter case, in the Minkowskian background the prerequisites for the existence of the nA clouds are (i) a large enough gauge group, and (ii) the presence of some extra interaction terms in the matter Lagrangian. To illustrate this mechanism we present two specific examples, one in four- and the other in five-dimensional asymptotically flat spacetime. In the first case, we augment the usual S U (3 ) Yang-Mills Lagrangian with a higher-order (quartic) curvature term, while for the second one we add the Chern-Simons density to the S O (6 ) Yang-Mills system. In both cases, an Abelian gauge symmetry is spontaneously broken near a RN black hole horizon with the appearance of a condensate of nA gauge fields. In addition to these two examples, we review the corresponding picture for anti-de Sitter black holes. All these solutions are studied both analytically and numerically, existence proofs being provided for nA clouds in the background of RN black holes. The proofs use shooting techniques which are suggested by and in turn offer insights for our numerical methods. They indicate that, for a black hole of given mass, appropriate electric charge values are required to ensure the existence of solutions interpolating desired boundary behavior at the horizons and spatial infinity.

FEL for the polymer processing industries

NASA Astrophysics Data System (ADS)

Kelley, Michael J.

1997-05-01

Polymers are everywhere in modern life because of their unique combination of end-use functionalities, ease of processing, recycling potential and modest cost. The physical and economic scope of the infrastructure committed to present polymers makes the introduction of entirely new chemistry unlikely. Rather, the breadth of commercial offerings more likely to shrink in the face of the widening mandate for recycling, especially of packaging. Improved performance and new functionality must therefore come by routes such as surface modification. However they must come with little environmental impact and at painfully low cost. Processing with strongly absorbed light offers unique advantages. The journal and patent literatures disclose a number of examples of benefits that can be achieved, principally by use of excimer lasers or special UV lamps. Examples of commercialization are few, however, because of the unit cost and maximum scale of existing light sources. A FEL, however, offers unique advantages: tunability to the optimum wavelength, potential for scale up to high average power, and a path to attractively low unit cost of light. A business analysis of prospective applications defines the technical and economic requirements a FEL for polymer surface processing must meet. These are compared to FEL technology as it now stands and as it is envisioned.

Virtual patients: practical advice for clinical authors using Labyrinth.

PubMed

Begg, Michael

2010-09-01

Labyrinth is a tool originally developed in the University of Edinburgh's Learning Technology Section for authoring and delivering branching case scenarios. The scenarios can incorporate game-informed elements such as scoring, randomising, avatars and counters. Labyrinth has grown more popular internationally since a version of the build was made available on the open source network Source Forge. This paper offers help and advice for clinical educators interested in creating cases. Labyrinth is increasingly recognised as a tool offering great potential for delivering cases that promote rich, situated learning opportunities for learners. There are, however, significant challenges to generating such cases, not least of which is the challenge for potential authors in approaching the process of constructing narrative-rich, context-sensitive cases in an unfamiliar authoring environment. This paper offers a brief overview of the principles informing Labyrinth cases (game-informed learning), and offers some practical advice to better prepare educators with little or no prior experience. Labyrinth has continued to grow and develop, from its roots as a research and development environment to one that is optimised for use by non-technical clinical educators. The process becomes increasingly iterative and better informed as the teaching community push the software further. The positive implications of providing practical advice and concept insight to new case authors is that it ideally leads to a broader base of users who will inform future iterations of the software. © Blackwell Publishing Ltd 2010.

26 CFR 1.1014-7 - Example applying rules of §§ 1.1014-4 through 1.1014-6 to case involving multiple interests.

Code of Federal Regulations, 2010 CFR

2010-04-01

... 26 Internal Revenue 11 2010-04-01 2010-04-01 true Example applying rules of §§ 1.1014-4 through... REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Basis Rules of General Application § 1.1014-7 Example applying rules of §§ 1.1014-4 through 1.1014-6 to case involving...

Microdiamond grade as a regionalised variable - some basic requirements for successful local microdiamond resource estimation of kimberlites

NASA Astrophysics Data System (ADS)

Stiefenhofer, Johann; Thurston, Malcolm L.; Bush, David E.

2018-04-01

Microdiamonds offer several advantages as a resource estimation tool, such as access to deeper parts of a deposit which may be beyond the reach of large diameter drilling (LDD) techniques, the recovery of the total diamond content in the kimberlite, and a cost benefit due to the cheaper treatment cost compared to large diameter samples. In this paper we take the first step towards local estimation by showing that micro-diamond samples can be treated as a regionalised variable suitable for use in geostatistical applications and we show examples of such output. Examples of microdiamond variograms are presented, the variance-support relationship for microdiamonds is demonstrated and consistency of the diamond size frequency distribution (SFD) is shown with the aid of real datasets. The focus therefore is on why local microdiamond estimation should be possible, not how to generate such estimates. Data from our case studies and examples demonstrate a positive correlation between micro- and macrodiamond sample grades as well as block estimates. This relationship can be demonstrated repeatedly across multiple mining operations. The smaller sample support size for microdiamond samples is a key difference between micro- and macrodiamond estimates and this aspect must be taken into account during the estimation process. We discuss three methods which can be used to validate or reconcile the estimates against macrodiamond data, either as estimates or in the form of production grades: (i) reconcilliation using production data, (ii) by comparing LDD-based grade estimates against microdiamond-based estimates and (iii) using simulation techniques.

A Model for Shear Layer Effects on Engine Noise Radiation

NASA Technical Reports Server (NTRS)

Nark, Douglas M.; Farassat, F.; Pope, D. Stuart; Vatsa, V.

2004-01-01

Prediction of aircraft engine noise is an important aspect of addressing the issues of community noise and cabin noise control. The development of physics based methodologies for performing such predictions has been a focus of Computational Aeroacoustics (CAA). A recent example of code development in this area is the ducted fan noise propagation and radiation code CDUCT-LaRC. Included within the code is a duct radiation model that is based on the solution of FfowcsWilliams-Hawkings (FW-H) equation with a penetrable data surface. Testing of this equation for many acoustic problems has shown it to provide generally better results than the Kirchhoff formula for moving surfaces. Currently, the data surface is taken to be the inlet or exhaust plane for inlet or aft-fan cases, respectively. While this provides reasonable results in many situations, these choices of data surface location lead to a few limitations. For example, the shear layer between the bypass ow and external stream can refract the sound waves radiated to the far field. Radiation results can be improved by including this effect, as well as the rejection of the sound in the bypass region from the solid surface external to the bypass duct surrounding the core ow. This work describes the implementation, and possible approximation, of a shear layer boundary condition within CDUCT-LaRC. An example application also illustrates the improvements that this extension offers for predicting noise radiation from complex inlet and bypass duct geometries, thereby providing a means to evaluate external treatments in the vicinity of the bypass duct exhaust plane.

A Large-Scale, Multiagency Approach to Defining a Reference Network for Pacific Northwest Streams

NASA Astrophysics Data System (ADS)

Miller, Stephanie; Eldred, Peter; Muldoon, Ariel; Anlauf-Dunn, Kara; Stein, Charlie; Hubler, Shannon; Merrick, Lesley; Haxton, Nick; Larson, Chad; Rehn, Andrew; Ode, Peter; Vander Laan, Jake

2016-12-01

Aquatic monitoring programs vary widely in objectives and design. However, each program faces the unifying challenge of assessing conditions and quantifying reasonable expectations for measured indicators. A common approach for setting resource expectations is to define reference conditions that represent areas of least human disturbance or most natural state of a resource characterized by the range of natural variability across a region of interest. Identification of reference sites often relies heavily on professional judgment, resulting in varying and unrepeatable methods. Standardized methods for data collection, site characterization, and reference site selection facilitate greater cooperation among assessment programs and development of assessment tools that are readily shareable and comparable. We illustrate an example that can serve the broader global monitoring community on how to create a consistent and transparent reference network for multiple stream resource agencies. We provide a case study that offers a simple example of how reference sites can be used, at the landscape level, to link upslope management practices to a specific in-channel response. We found management practices, particularly areas with high road densities, have more fine sediments than areas with fewer roads. While this example uses data from only one of the partner agencies, if data were collected in a similar manner they can be combined and create a larger, more robust dataset. We hope that this starts a dialog regarding more standardized ways through inter-agency collaborations to evaluate data. Creating more consistency in physical and biological field protocols will increase the ability to share data.

Hyperspectral Sulfur Detection Using an SVM with Extreme Minority Positive Examples Onboard EO-1

NASA Astrophysics Data System (ADS)

Mandrake, Lukas; Wagstaff, Kiri L.; Gleeson, Damhnait; Rebbapragada, Umaa; Tran, Daniel; Castano, Rebecca; Chien, Steven; Pappalardo, Robert T.

2009-09-01

Onboard classification of remote sensing data is of general interest given that it can be used as a trigger to initiate alarms, data download, additional higher- resolution scans, or more frequent scans of an area without ground interaction. In our case, we study the sulfur-rich Borup-Fiord glacial springs in Canada utilizing the Hyperion instrument aboard the EO-1 spacecraft. This system consists of naturally occurring sulfur-rich springs emerging from glacial ice, which are a known environment for microbial life. The biological activity of the spring is associated with sulfur compounds that can be detected remotely via spectral analysis. This system may offer an analog to far more exotic locales such as Europa where remote sensing of biogenic indicators is of considerable interest. Unfortunately, spacecraft processing power and memory is severely limited which places strong constraints on the algorithms available. Previous work has been performed in the generation and execution of an onboard SVM (support vector machine) classifier to autonomously identify the presence of sulfur compounds associated with the activity of microbial life. However, those results were limited in the number of positive examples available to be labeled. In this paper we extend the sample size from 1 to 7 example scenes between 2006 and 2008, corresponding to a change from 18 to 235 positive labels. Of key interest is our assessment of the classifier's behavior on non-sulfur-bearing imagery far from the training region. Selection of the most relevant spectral bands and parameters for the SVM are also explored.

An Example of a Practical Biochemistry Examination for Health Professional Students.

ERIC Educational Resources Information Center

Otsuka, Allen; Kadis, Barney

1988-01-01

Uses clinical cases taken from the medical or dental literature for examination of understanding certain aspects of the dental profession. Formulates questions derived from data presented in the case or attempts to present broad principles. Includes 15 example test questions. (MVL)

Simulating Laboratory Procedures.

ERIC Educational Resources Information Center

Baker, J. E.; And Others

1986-01-01

Describes the use of computer assisted instruction in a medical microbiology course. Presents examples of how computer assisted instruction can present case histories in which the laboratory procedures are simulated. Discusses an authoring system used to prepare computer simulations and provides one example of a case history dealing with fractured…

Alternative Splicing in the Hippo Pathway—Implications for Disease and Potential Therapeutic Targets

PubMed Central

Porazinski, Sean; Ladomery, Michael

2018-01-01

Alternative splicing is a well-studied gene regulatory mechanism that produces biological diversity by allowing the production of multiple protein isoforms from a single gene. An involvement of alternative splicing in the key biological signalling Hippo pathway is emerging and offers new therapeutic avenues. This review discusses examples of alternative splicing in the Hippo pathway, how deregulation of these processes may contribute to disease and whether these processes offer new potential therapeutic targets. PMID:29534050

Advice offered by practitioners of complementary/ alternative medicine: an important ethical issue.

PubMed

Ernst, E

2009-12-01

The current popularity of complementary/alternative medicine (CAM) generates many challenges to medical ethics. The one discussed here is the advice offered by CAM practitioners. Using selected examples, the author tries to demonstrate that some of the advice issued through the popular media or provided by acupuncturists, chiropractors, herbalists, homeopaths, pharmacists, and doctors is misleading or dangerous. This, the author argues, can impinge on the main principle of medical ethics: beneficence, nonmaleficence, and autonomy. We should work toward correcting this deplorable situation.

Case studies on design, simulation and visualization of control and measurement applications using REX control system

NASA Astrophysics Data System (ADS)

Ozana, Stepan; Pies, Martin; Docekal, Tomas

2016-06-01

REX Control System is a professional advanced tool for design and implementation of complex control systems that belongs to softPLC category. It covers the entire process starting from simulation of functionality of the application before deployment, through implementation on real-time target, towards analysis, diagnostics and visualization. Basically it consists of two parts: the development tools and the runtime system. It is also compatible with Simulink environment, and the way of implementation of control algorithm is very similar. The control scheme is finally compiled (using RexDraw utility) and uploaded into a chosen real-time target (using RexView utility). There is a wide variety of hardware platforms and real-time operating systems supported by REX Control System such as for example Windows Embedded, Linux, Linux/Xenomai deployed on SBC, IPC, PAC, Raspberry Pi and others with many I/O interfaces. It is modern system designed both for measurement and control applications, offering a lot of additional functions concerning data archiving, visualization based on HTML5, and communication standards. The paper will sum up possibilities of its use in educational process, focused on control of case studies of physical models with classical and advanced control algorithms.

How Intersectoral Health Promotion Changes Professional Practices: A Case Study From Denmark.

PubMed

Christensen, Mads; Burau, Viola; Ledderer, Loni

2018-05-01

Intersectoral health promotion (IHP) has pushed health professions to engage in new tasks and interprofessional ways of working. We studied how care assistants from a nursing home and school teachers implemented a cookery project targeted at children ("Cool Beans") as an example of an IHP project in Denmark. Our aim was to examine the impact of the IHP project on the practices of the professions involved. We used a qualitative case study to investigate joint care and teaching situations with the two professions and their users. Our data consisted of documents, participatory observations, and informal interviews (17 hours) as well as semistructured interviews with professionals (n = 4). We used a sociological institutional framework to analyze the professional practices emerging in joint care and teaching situations and identified three themes of new professional activities: (1) "interplay" related to making different generations collaborate on the tasks involved in the cookery session; (2) "care" concerned with caregiving activities; and (3) "learning" focused on schooling on healthy food and cooking. We conclude that changes in professional practices occurred informally and were induced by the concrete activities in the cookery project. The specific, practical tasks of the IHP project thus offered an important leverage for future interprofessional collaborations.

Teaching the Ethical Aspects of Environmental Science

NASA Astrophysics Data System (ADS)

Palinkas, C. M.

2014-12-01

Environmental and societal issues are often inherently linked, especially in coastal and estuarine environments, and science and social values must often be balanced in ecosystem management and decision-making. A new seminar course has been developed for the Marine Estuarine and Environmental Science (MEES) graduate program, an inter-institutional program within the University System of Maryland, to examine these issues. This 1-credit course, offered for the first time in Spring 2015, takes a complex systems perspective on major environmental and societal challenges to examine these linked issues in a variety of contexts. After a brief introduction to the emerging field of "geoethics," students develop a list of issues to examine throughout the seminar. Example topics could include fracking, offshore wind technology, dam removal, and iron fertilization, among others. A case-study approach is taken, with each class meeting focusing on one issue. For each case study, students are asked to 1) identify relevant scientific principles and major knowledge gaps, 2) predict potential outcomes, 3) identify stakeholders and likely viewpoints, and 4) construct communication plans to disseminate findings to these stakeholders. At the end of the semester, students give a brief presentation of the ethical aspects of their own research topics.

Empowerment Praxis: Community Organizing to Redress Systemic Health Disparities.

PubMed

Douglas, Jason A; Grills, Cheryl T; Villanueva, Sandra; Subica, Andrew M

2016-12-01

Social and environmental determinants of childhood obesity present a public health dilemma, particularly in low-income communities of color. Case studies of two community-based organizations participating in the Robert Wood Johnson Foundation's Communities Creating Healthy Environments (CCHE) childhood obesity initiative demonstrate multilevel, culturally situated community organizing strategies to address the root causes of this public health disparity. Informed by a 3-lens prescription-Social Justice, Culture-Place, and Organizational Capacity-contained in the CCHE Change Model and Evaluation Frame, we present examples of individual, organizational, and community empowerment to redress systemic inequities that manifest in poor health outcomes for people of color. These case studies offer compelling evidence that public health disparities in these communities may effectively be abated through strategies that employ bottom-up, community-level approaches for (a) identifying proximal and distal determinants of public health disparities, and (b) empowering communities to directly redress these inequities. Guided by this ecological framework, application of the CCHE evaluation approach demonstrated the necessity to document the granularity of community organizing for community health, adding to the community psychology literature on empowering processes and outcomes. © Society for Community Research and Action 2016.

Potential application of the consistency approach for vaccine potency testing.

PubMed

Arciniega, J; Sirota, L A

2012-01-01

The Consistency Approach offers the possibility of reducing the number of animals used for a potency test. However, it is critical to assess the effect that such reduction may have on assay performance. Consistency of production, sometimes referred to as consistency of manufacture or manufacturing, is an old concept implicit in regulation, which aims to ensure the uninterrupted release of safe and effective products. Consistency of manufacture can be described in terms of process capability, or the ability of a process to produce output within specification limits. For example, the standard method for potency testing of inactivated rabies vaccines is a multiple-dilution vaccination challenge test in mice that gives a quantitative, although highly variable estimate. On the other hand, a single-dilution test that does not give a quantitative estimate, but rather shows if the vaccine meets the specification has been proposed. This simplified test can lead to a considerable reduction in the number of animals used. However, traditional indices of process capability assume that the output population (potency values) is normally distributed, which clearly is not the case for the simplified approach. Appropriate computation of capability indices for the latter case will require special statistical considerations.

[Hemoglobinopathies. Current therapeutic possibilities].

PubMed

Birgens, H S; Karle, H

1995-05-29

In recent years, the number of immigrants has increased considerably in Denmark. Consequently, a series of new clinical pictures has appeared in the Danish health care system. Typical examples are the genetic diseases, the haemoglobinopathies. Most of the immigrants come from areas, where the gene frequency of these disorders is widely distributed, for instance the Mediterranean countries, the Middle East, Southeast Asia and Africa. Most frequent are the heterozygous thalassaemias, but also the number of patients with severe thalassaemia and other clinically important haemoglobinopathies such as sickle cell anaemia has also increased in recent years. The clinical problems concerning these patients focus on two important topics, namely genetic counselling of heterozygous individuals (in some cases combined with prenatal diagnostics) and the treatment of patients with clinically severe haemoglobinopathy. The only curative treatment of the haemoglobinopathies is allogeneic bone marrow transplantation, but this treatment can only be offered to a few of these patients. However, a variety of therapeutic options exist which can improve their prognosis and quality of life. Since the number of patients with these diseases will probably increase over the next years we find it relevant, based on typical case stories, to give a review of the present therapeutic possibilities for these disorders.

In defence of mandatory bicycle helmet legislation: response to Hooper and Spicer.

PubMed

Biegler, Paul; Johnson, Marilyn

2015-08-01

We invoke a triple rationale to rebut Hooper and Spicer's argument against mandatory helmet laws. First, we use the laws of physics and empirical studies to show how bicycle helmets afford substantial protection to the user. We show that Hooper and Spicer erroneously downplay helmet utility and that, as a result, their attack on the utilitarian argument for mandatory helmet laws is weakened. Next, we refute their claim that helmet legislation comprises unjustified paternalism. We show the healthcare costs of bareheaded riding to pose significant third party harms. It follows, we argue, that a utilitarian case for helmet laws can be sustained by appeal to Mill's Harm Principle. Finally, we reject Hooper and Spicer's claim that helmet laws unjustly penalise cyclists for their own health-affecting behaviour. Rather, we show their argument to suffer by disanalogy with medical cases where injustice may be more evident, for example, denial of bypass surgery to smokers. We conclude that mandatory helmet laws offer substantial utility and are entirely defensible within the framework of a liberal democracy. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Measuring resilience of coupled human-water systems using ecosystem services compatible indicators

NASA Astrophysics Data System (ADS)

Hannah, D. M.; Mao, F.; Karpouzoglou, T.; Clark, J.; Buytaert, W.

2017-12-01

To explore the dynamics of socio-hydrological systems under change, the concepts of resilience and ecosystem services serve as useful tools. In this context, resilience refers to the capacity of a socio-hydrological system to retain its structural and functional state despite perturbations, while ecosystem services offer a good proxy of the state that reflects human-water intersections. Efforts are needed to maintain and improve socio-hydrological resilience for future contingencies to secure hydrological ecosystem services supply. This requires holistic indicators of resilience for coupled human-water systems that are essential for quantitative assessment, change tracking, inter-case comparison, as well as resilience management. However, such indicators are still lacking. Our research aims to propose widely applicable resilience indicators that are suitable for the coupled human-water context, and compatible with ecosystem services. The existing resilience indicators for both eco-hydrological and socio-economic sectors are scrutinised, screened and analysed to build these new indicators. Using the proposed indicators, we compare the resilience and its temporal change among a set of example regions, and discusses the linkages between socio-hydrological resilience and hydrological ecosystem services with empirical cases.

Diameter Versus Mass in the Development of the Orion Life Support Umbilical: A Case Study in Systems Engineering

NASA Technical Reports Server (NTRS)

Jordan, Nicole; Falconi, Eric; Barido, Richard; Lewis, John

2009-01-01

Systems engineering could also be called the art of compromise. At its heart, systems engineering seeks to find that solution which maximizes the utility of the system, usually compromising the performance of each individual subsystem. While seemingly straightforward, systems engineering methodology is complicated when the utility to be maximized is unclear and the costs to each individual subsystem are not - or not easily - quantifiable. In this paper, we explore one such systems engineering problem within the Constellation Program as a case study in applied systems engineering. During suited operations, astronauts within Orion will be connected to an umbilical to receive and return breathing gas. The pressure drop associated with this umbilical must be overcome by the Orion vehicle. A smaller umbilical, which is desirable for crew operations, means a higher pressure drop, resulting in additional mass and power for the vehicle. We outline the technical considerations in the development of this integrated system and discuss the method by which we reached the ultimate solution. This paper, while just one example of the kind of problem solving that happens every day, offers insight into what happens when the theories of systems engineering are put into practice.

Blending technology in teaching advanced health assessment in a family nurse practitioner program: using personal digital assistants in a simulation laboratory.

PubMed

Elliott, Lydia; DeCristofaro, Claire; Carpenter, Alesia

2012-09-01

This article describes the development and implementation of integrated use of personal handheld devices (personal digital assistants, PDAs) and high-fidelity simulation in an advanced health assessment course in a graduate family nurse practitioner (NP) program. A teaching tool was developed that can be utilized as a template for clinical case scenarios blending these separate technologies. Review of the evidence-based literature, including peer-reviewed articles and reviews. Blending the technologies of high-fidelity simulation and handheld devices (PDAs) provided a positive learning experience for graduate NP students in a teaching laboratory setting. Combining both technologies in clinical case scenarios offered a more real-world learning experience, with a focus on point-of-care service and integration of interview and physical assessment skills with existing standards of care and external clinical resources. Faculty modeling and advance training with PDA technology was crucial to success. Faculty developed a general template tool and systems-based clinical scenarios integrating PDA and high-fidelity simulation. Faculty observations, the general template tool, and one scenario example are included in this article. ©2012 The Author(s) Journal compilation ©2012 American Academy of Nurse Practitioners.

Sherlock Holmes and the case of the plagiarised paper.

PubMed

Kennedy, David

2011-07-01

Narrative pedagogy has the power to explore issues in a way that expository teaching cannot match. Moon and Fowler (2008, p.236), for example, point out that fiction has much to offer in focusing creatively on issues, exploring subtleties and discussing related emotional dynamics. But they comment that in nurse education fiction is 'a relatively untapped' (though valuable) resource for teaching. 'Sherlock Holmes and the Case of the Plagiarised Paper' is a fictional account that responds to Moon and Fowler's challenge. It explores a controversial issue--student plagiarism. The narrative sets the discussion in a fictional context--an interaction between fictional characters and a real character. It explores difficulties that novice writers have in avoiding plagiarism. It debates how teachers may respond to student plagiarism. It contextualises student plagiarism in the wider world of academic plagiarism. Its purpose is to enable the reader to identify and act on these issues in a way that an expository examination of student plagiarism could not achieve. In response to suggestions from reviewers, the article has an Appendix which outlines some of the issues and techniques associated with the use of fiction in nursing education. Copyright © 2010 Elsevier Ltd. All rights reserved.

Eco-Balance analysis of the disused lead-acid-batteries recycling technology

NASA Astrophysics Data System (ADS)

Kamińska, Ewa; Kamiński, Tomasz

2017-10-01

The article presents the results of the eco-balance analysis of the disused lead-acid batteries recycling process. Test-dedicated technology offers the possibility to recover other elements, for example, polypropylene of the battery case or to obtain crystalline sodium sulphate. The life cycle assessment was made using ReCiPe and IMPACT2002 + methods. The results are shown as environmental points [Pt]. The results are shown in the environmental categories, specific for each of the methods grouped in the impact categories. 1 Mg of the processed srap was a dopted as the functional unit. The results of the analyses indicate that recycling processes may provide the environmental impact of recycling technology less harmful. Repeated use of lead causes that its original sources are not explored. Similarly, the use of granule production-dedicated polypropylene extracted from battery casings that are used in the plastics industry, has environmental benefits. Due to the widespread use of lead-acid batteries, the attention should be paid to their proper utilization, especially in terms of heavy metals, especially lead. According to the calculations, the highest level of environmental benefits from the use of lead from secondary sources in the production of new products, was observed in the refining process.

Nonlinear Pattern Selection in Bi-Modal Interfacial Instabilities

NASA Astrophysics Data System (ADS)

Picardo, Jason; Narayanan, Ranga

2016-11-01

We study the evolution of two interacting unstable interfaces, with the aim of understanding the role of non-linearity in pattern selection. Specifically, we consider two superposed thin films on a heated surface, that are susceptible to thermocapillary and Rayleigh-Taylor instabilities. Due to the presence of two unstable interfaces, the dispersion curve (linear growth rate plotted as a function of the perturbation wavelength) exhibits two peaks. If these peaks have equal heights, then the two corresponding disturbance patterns will grow with the same linear growth rate. Therefore, any selection between the two must occur via nonlinear effects. The two-interface problem under consideration provides a variety of such bi-modal situations, in which the role of nonlinearity in pattern selection is unveiled. We use a combination of long wave asymptotics, numerical simulations and amplitude expansions to understand the subtle nonlinear interactions between the two peak modes. Our results offer a counter-example to Rayleigh's principle of pattern formation, that the fastest growing linear mode will dominate the final pattern. Far from being governed by any such general dogma, the final selected pattern varies considerably from case to case. The authors acknowledge funding from NSF (0968313) and the Fulbright-Nehru fellowship.

Assessing Social – Ecological Trade-Offs to Advance Ecosystem-Based Fisheries Management

PubMed Central

Voss, Rudi; Quaas, Martin F.; Schmidt, Jörn O.; Tahvonen, Olli; Lindegren, Martin; Möllmann, Christian

2014-01-01

Modern resource management faces trade-offs in the provision of various ecosystem goods and services to humanity. For fisheries management to develop into an ecosystem-based approach, the goal is not only to maximize economic profits, but to consider equally important conservation and social equity goals. We introduce such a triple-bottom line approach to the management of multi-species fisheries using the Baltic Sea as a case study. We apply a coupled ecological-economic optimization model to address the actual fisheries management challenge of trading-off the recovery of collapsed cod stocks versus the health of ecologically important forage fish populations. Management strategies based on profit maximization would rebuild the cod stock to high levels but may cause the risk of stock collapse for forage species with low market value, such as Baltic sprat (Fig. 1A). Economically efficient conservation efforts to protect sprat would be borne almost exclusively by the forage fishery as sprat fishing effort and profits would strongly be reduced. Unless compensation is paid, this would challenge equity between fishing sectors (Fig. 1B). Optimizing equity while respecting sprat biomass precautionary levels would reduce potential profits of the overall Baltic fishery, but may offer an acceptable balance between overall profits, species conservation and social equity (Fig. 1C). Our case study shows a practical example of how an ecosystem-based fisheries management will be able to offer society options to solve common conflicts between different resource uses. Adding equity considerations to the traditional trade-off between economy and ecology will greatly enhance credibility and hence compliance to management decisions, a further footstep towards healthy fish stocks and sustainable fisheries in the world ocean. PMID:25268117

When holistic care is not holistic enough: The role of sexual health in mental health settings.

PubMed

Hendry, Avril; Snowden, Austyn; Brown, Michael

2018-03-01

To explore the preparation that mental health nurses receive to address sexual health in practice. People who use the mental health services often have complex sexual health needs. Mental health nurses are well placed to offer support. However, this rarely happens in practice, and therefore, people's sexual health needs are not being routinely addressed. It is not known why this is the case. Systematic review and meta-ethnography. EBSCO, PsycINFO, MEDLINE and ASSIA databases were searched using Booleans with Mesh and key terms including "mental health nurse" and "sexual health". Date range was June 2006 to June 2016. Discursive papers were excluded. Included papers (n = 7) were synthesised using a meta-ethnographic approach. The search yielded seven studies. Five key themes were identified: the (not so) therapeutic relationship; personal values dictating professional ones; institutionalised fear; being human; and education: the answer but where is it? The findings illustrate the complexity of supporting people with mental health and sexual health needs. They show the discomfort many nurses have about broaching sexual health. Arguably more than with most issues, personal values impacted strongly on professional practice. Understanding the depth and multifaceted nature of these themes is important, because strategies can then be developed to mitigate the barriers to best practice. For example, the findings presented here offer a framework from which structured education and support can be built. There is a need for Mental health nurses to be more responsive to concerns around sexual health and it should be routinely included in their practice. This study illuminates why this is not currently the case. By understanding this, remedial action can be taken by nurse educators. Implications are also discussed in relation to policy, research and practice. © 2017 John Wiley & Sons Ltd.