NASA Astrophysics Data System (ADS)
Viallon, Joële; Moussay, Philippe; Wielgosz, Robert; Morillo Gomez, Pilar; Sánchez Blaya, Carmen
2009-01-01
As part of the on-going key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of the Instituto de Salud Carlos III (ISCIII) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM). The instruments have been compared over a nominal ozone mole fraction range of 0 nmol/mol to 500 nmol/mol. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Viallon, Joële; Moussay, Philippe; Idrees, Faraz; Wielgosz, Robert; Sanchez, Carmen; Morillo Gomez, Pilar
2015-01-01
As part of the ongoing key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of the Instituto de Salud Carlos III (ISCIII) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM). The instruments have been compared over a nominal ozone amount-of-substance fraction range of 0 nmol/mol to 500 nmol/mol. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Viallon, Joële; Moussay, Philippe; Idrees, Faraz; Wielgosz, Robert; Morillo Gomez, Pilar; Sánchez, Carmen
2011-01-01
As part of the ongoing key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of the Instituto de Salud Carlos III (ISCIII) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM). The instruments have been compared over a nominal ozone amount-of-substance fraction range of 0 nmol/mol to 500 nmol/mol. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Viallon, Joële; Moussay, Philippe; Wielgosz, Robert; Sanchez, Carmen; Morillo Gomez, Pilar
2017-01-01
As part of the ongoing key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of the Instituto de Salud Carlos III (ISCIII) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM). The instruments have been compared over a nominal ozone amount-of-substance fraction range of 0 nmol/mol to 500 nmol/mol. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Viallon, Joële; Moussay, Philippe; Idrees, Faraz; Wielgosz, Robert; Morillo Gomez, Pilar; Sánchez, Carmen
2013-01-01
As part of the ongoing key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of the Instituto de Salud Carlos III (ISCIII) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM). The instruments have been compared over a nominal ozone amount-of-substance fraction range of 0 nmol/mol to 500 nmol/mol. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Viallon, Joële; Idrees, Faraz; Moussay, Philippe; Wielgosz, Robert; Sweeney, Bryan; Quincey, Paul
2018-01-01
As part of the ongoing key comparison BIPM.QM-K1, a comparison has been performed between the ozone standard of the United Kingdom maintained by the National Physical Laboratory (NPL) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM). The instruments have been compared over a nominal ozone amount-of-substance fraction range of 0 nmol/mol to 500 nmol/mol. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Viallon, Joële; Moussay, Philippe; Wielgosz, Robert; Heikens, Dita; van der Veen, Adrian
2017-01-01
As part of the ongoing key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of the Netherlands maintained by the Van Swinden (VSL) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM). The instruments have been compared over a nominal ozone amount-of-substance fraction range from 0 nmol/mol to 500 nmol/mol Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Viallon, Joële; Moussay, Philippe; Wielgosz, Robert; Hodges, Joe; Norris, James E.
2017-01-01
As part of the ongoing key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of the National Institute of Standards and Technology (NIST) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM). The instruments have been compared over a nominal ozone amount-of-substance fraction range of 0 nmol/mol to 500 nmol/mol. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Viallon, Joële; Idrees, Faraz; Moussay, Philippe; Wielgosz, Robert; Fentanes, Oscar; Benítez, Ángeles; Ordoñez, Daniel
2018-01-01
As part of the ongoing key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of Mexico maintained by the National Institute of Ecology and Climate Change (INECC) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM). The instruments have been compared over a nominal ozone amount-of-substance fraction range from 0 nmol/mol to 500 nmol/mol. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Viallon, Joële; Idrees, Faraz; Moussay, Philippe; Wielgosz, Robert; Lin, Tsai-Yin; Norris, James E.; Hodges, Joseph T.
2017-01-01
As part of the on-going key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of the ITRI Center for Measurement Standards (CMS-ITRI) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM), via a transfer standard maintained by the National Institute of Standards and Technology (NIST). The instruments have been compared over a nominal ozone amount-of-substance fraction range of 0 nmol/mol to 500 nmol/mol. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Viallon, J.; Moussay, P.; Wielgosz, R.; Bebic, J.; Norris, J. E.; Guenther, F.
2016-01-01
As part of the on-going key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of the Directorate of Measures and Precious Metals (DMDM) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM), via a transfer standard maintained by the National Institute of Standards and Technology (NIST). The instruments have been compared over a nominal ozone amount-of-substance fraction range of 0 nmol/mol to 500 nmol/mol Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Viallon, Joële; Idrees, Faraz; Moussay, Philippe; Wielgosz, Robert; Ntsasa, Napo G.; Tshilongo, James; Mphaphuli, Gumani E.; Norris, James E.; Hodges, Joseph T.
2018-01-01
As part of the on-going key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of South Africa maintained by the National Metrology Institute of South Africa (NMISA) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM), via a transfer standard maintained by the National Institute of Standards and Technology (NIST). The instruments have been compared over a nominal ozone amount-of-substance fraction range of 0 nmol/mol to 500 nmol/mol. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Goebel, R.; Power, O.; Fletcher, N.; Stock, M.
2012-01-01
This report describes the results obtained from a NML(Ireland)-BIPM bilateral comparison of 1 Ω resistance standards in 2010. The comparison was carried out in the framework of the BIPM ongoing key comparison BIPM.EM-K13.a. Two BIPM 1 Ω travelling standards of CSIRO type were calibrated first at the BIPM, then at the NMLI and again at the BIPM after their return. The stability of the transfer standard was such that the uncertainty associated with the transfer was significantly smaller than the uncertainty arising from the calibrations. The mean difference between the NMLI and the BIPM calibrations was found to be just within the expanded uncertainty (k = 2) of the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Goebel, R.; Kurupakorn, C.; Fletcher, N.; Stock, M.
2010-01-01
This report describes the results obtained from a NIMT (Thailand)-BIPM bilateral comparison of 10 kΩ resistance standards in 2009. The comparison was carried out in the framework of the BIPM ongoing key comparison BIPM.EM-K13.b. Two BIPM 10 kΩ travelling standards of SR104 type were calibrated first at the BIPM, then at the NMIT and again at the BIPM after their return. The stability of the transfer standards was such that the uncertainty associated with the transfer was smaller than the uncertainty arising from the calibrations. The mean difference between the NIMT and the BIPM calibrations was found to be significantly larger than the expanded uncertainty (k = 2) of the comparison. However, this exercise allowed previously undetected sources of errors to be detected in the NIMT facility. A new bilateral comparison can be organized as soon as these problems are fixed. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Gournay, Pierre; Helmy, M.; Raouf, A.; Hamed, Heba A. M.; Eliwa Gad, A.
2017-01-01
This report presents the results of a bilateral comparison of 10 pF and 100 pF capacitance standards between the NIS (Egypt) and the BIPM carried out in 2016. The comparison at 10 pF forms part of the ongoing BIPM key comparison BIPM.EM-K14.a and that at 100 pF of the ongoing BIPM key comparison BIPM.EM-K14.b. The BIPM is the pilot laboratory for both of these comparisons. Two 10 pF and 100 pF travelling standards belonging to the BIPM were used in this comparison carried out with an 'A-B-A' pattern of measurements. The standards were measured first at the BIPM for a period of about one month, then for a similar period at the NIS, and finally again at the BIPM. The measurand was the two terminal-pair capacitance at a frequency of either 1000 Hz or 1592 Hz, for a measuring rms voltage of 15 V at 10 pF and 10 V at 100 pF. One of the 10 pF travelling standards had to be eliminated from the comparison due to a bistable behaviour, possibly due to transportation. The results from the NIS and the BIPM at both 1000 Hz and 1592 Hz were found to be in good agreement, with a difference smaller than the relative expanded uncertainty (95 % confidence, k = 2) of about 0.72 × 10-6 at 10 pF and about 0.65 × 10-6 at 100 pF. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Goebel, R.; Power, O.; Fletcher, N.; Stock, M.
2012-01-01
This report describes the results obtained from a NML(Ireland)-BIPM bilateral comparison of 10 kΩ resistance standards in 2010. The comparison was carried out in the framework of the BIPM ongoing key comparison BIPM.EM-K13.b. Two BIPM 10 kΩ travelling standards of SR104 type were calibrated first at the BIPM, then at the NMLI and again at the BIPM after their return. The stability of the transfer standards was such that the uncertainty associated with the transfer was significantly smaller than the uncertainty arising from the calibrations. The NMLI and the BIPM calibrations were found to be in agreement, with a mean difference smaller than the standard uncertainty of the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Gournay, Pierre; Khoza, Michael
2017-01-01
This report presents the results of a bilateral comparison of 10 pF and 100 pF capacitance standards between the NMISA (South Africa) and the BIPM carried out in 2016. The comparison at 10 pF forms part of the ongoing BIPM key comparison BIPM.EM-K14.a and that at 100 pF of the ongoing BIPM key comparison BIPM.EM-K14.b. The BIPM is the pilot laboratory for both of these comparisons. Two 10 pF and 100 pF travelling standards belonging to the BIPM were used in this comparison carried out with an 'A-B-A' pattern of measurements. The standards were measured first at the BIPM for a period of about one month, then for a similar period at the NMISA, and finally again at the BIPM. The measurand was the two terminal-pair capacitance at a frequency of either 1000 Hz or 1592 Hz, for a measuring rms voltage of 15 V at 10 pF and 10 V at 100 pF. One of the 10 pF travelling standards had to be eliminated from the comparison due to a bistable behaviour, possibly due to transportation. The results from the NMISA and the BIPM at both 1000 Hz and 1592 Hz were found to be in good agreement, with a difference smaller than the relative expanded uncertainty (95 % confidence, k = 2) of maximum value 0.33 × 10-6 at 10 pF and 0.24 × 10-6 at 100 pF (and 1000 Hz in both cases). Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Sapunova, I.; Fletcher, N.; Goebel, R.; Stock, M.
2015-01-01
This report gives the result of a bilateral comparison of capacitance between the BIM (Bulgaria) and the BIPM carried out in 2012. Two 100 pF travelling standards belonging to the BIPM were used. The comparison was carried out with an 'A-B-A' pattern of measurements; the standards were measured first at the BIPM for a period of about one month, then for a similar period at the BIM, and finally again at the BIPM. The measurand was the two terminal-pair capacitance at a frequency of 1000 Hz and for a measuring voltage of 15 V. The BIPM was the pilot laboratory, and the comparison forms part of the ongoing BIPM key comparison BIPM.EM-K14.a. The results from the BIM and the BIPM were found to be in good agreement, with a difference smaller than the relative expanded uncertainty (95% confidence, k = 2) of 1.1 × 10-6. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Sapunova, I.; Fletcher, N.; Goebel, R.; Stock, M.
2015-01-01
This report gives the result of a bilateral comparison of capacitance between the BIM (Bulgaria) and the BIPM carried out in 2012. Two 10 pF travelling standards belonging to the BIPM were used. The comparison was carried out with an 'A-B-A' pattern of measurements; the standards were measured first at the BIPM for a period of about one month, then for a similar period at the BIM, and finally again at the BIPM. The measurand was the two terminal-pair capacitance at a frequency of 1000 Hz and for a measuring voltage of 15 V. The BIPM was the pilot laboratory, and the comparison forms part of the ongoing BIPM key comparison BIPM.EM-K14.a. The results from the BIM and the BIPM were found to be in good agreement, with a difference smaller than the relative expanded uncertainty (95% confidence, k = 2) of 1.1 × 10-6. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Power, O.; Moran, A.; Fletcher, N.; Goebel, R.; Stock, M.
2015-01-01
This report gives the result of a bilateral comparison of capacitance between the NSAI-NML (Ireland) and the BIPM carried out in 2011. Two 100 pF travelling standards belonging to the BIPM were used. The comparison was carried out with an 'A-B-A' pattern of measurements; the standards were measured first at the BIPM for a period of about one month, then for a similar period at the NSAI-NML, and finally again at the BIPM. The measurand was the two terminal-pair capacitance at a frequency of 1000 Hz, for a measuring voltage of 15 V. The BIPM was the pilot laboratory, and the comparison forms part of the ongoing BIPM key comparison BIPM.EM-K14.b. The results from the NSAI-NML and the BIPM were found to be in good agreement, with a difference smaller than the relative expanded uncertainty (95 % confidence, k = 2) of 0.66 × 10-6. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Power, O.; Moran, A.; Fletcher, N.; Goebel, R.; Stock, M.
2015-01-01
This report gives the result of a bilateral comparison of capacitance between the NSAI-NML (Ireland) and the BIPM carried out in 2011. Two 10 pF travelling standards belonging to the BIPM were used. The comparison was carried out with an 'A—B—A' pattern of measurements; the standards were measured first at the BIPM for a period of about one month, then for a similar period at the NSAI-NML, and finally again at the BIPM. The measurand was the two terminal-pair capacitance at a frequency of 1000 Hz for a measuring voltage of 15 V. The BIPM was the pilot laboratory, and the comparison forms part of the ongoing BIPM key comparison BIPM.EM-K14.a. The results from the NSAI-NML and the BIPM were found to be in good agreement, with a difference smaller than the relative expanded uncertainty (95 % confidence, k = 2) of 2.5 × 10-6. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Gournay, Pierre; Power, Oliver
2017-01-01
This report presents the results of a bilateral comparison of capacitance at 100 pF between the NSAI-NML (Ireland) and the BIPM carried out in 2016. This comparison forms part of the ongoing BIPM key comparison BIPM.EM-K14.b in which the BIPM is the pilot laboratory. Two 100 pF travelling standards belonging to the BIPM were used in this comparison carried out with an 'A-B-A' pattern of measurements. The standards were measured first at the BIPM for a period of about one month, then for a similar period at the NSAI-NML, and finally again at the BIPM. The measurand was the two terminal-pair capacitance at a frequency of 1000 Hz, for a measuring rms voltage of 15 V. The results from the NSAI-NML and the BIPM were found to be in relatively good agreement, with a difference smaller than the relative expanded uncertainty (95 % confidence, k = 2) of 0.85 × 10-6. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Power, O.; Solve, S.; Chayramy, R.; Stock, M.
2011-01-01
As a part of the ongoing BIPM key comparison BIPM.EM-K11.b, a comparison of the 10 V voltage reference standards of the BIPM and the National Standards Authority of Ireland-National Metrology Laboratory (NSAI-NML), Dublin, Ireland, was carried out from March to April 2011. Two BIPM Zener diode-based travelling standards (Fluke 732B) were transported by freight to NSAI-NML. At NSAI-NML, the 10 V output EMF of each travelling standard was measured by direct comparison with a group of characterized Zener diode-based electronic voltage standards. At the BIPM, the travelling standards were calibrated before and after the measurements at NSAI-NML, with the Josephson Voltage Standard. Results of all measurements were corrected for the dependence of the output voltages on internal temperature and ambient pressure. The comparison results show that the voltage standards maintained by NSAI-NML and the BIPM were equivalent, within their stated expanded uncertainties, on the mean date of the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Rolland, B.; Fletcher, N.; Khumthukthit, N.; Jassadajin, C.
2017-01-01
This report gives the result of a bilateral comparison of resistance between the NIMT (Thailand) and the BIPM carried out in 2015. Two 1 Ω and two 10 kΩ travelling standards belonging to the BIPM were used. The comparison was carried out with an 'A-B-A' pattern of measurements; the standards were measured first at the BIPM for a period of about one month, then for a similar period at the BIM, and finally again at the BIPM. The measurand was the 4 terminal dc resistance at low power. The BIPM was the pilot laboratory, and the comparison forms part of the ongoing BIPM key comparisons BIPM.EM-K13.a (for 1 Ω) and BIPM.EM-K13b (for 10 kΩ). The results from the NIMT and the BIPM were found to be in good agreement, with a difference smaller than the relative expanded uncertainty (95% confidence, k = 2) of 0.20 × 10-6 for 1 Ω and 0.74 × 10-6 for 10 kΩ. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Rolland, Benjamin; Fletcher, Nick; Vlad, Dana
2017-01-01
This report gives the result of a bilateral comparison of resistance between the SMD (Belgium) and the BIPM carried out in 2017. Two 1 Ω and two 10 kΩ travelling standards belonging to the BIPM were used. The comparison was carried out with an 'A-B-A' pattern of measurements; the standards were measured first at the BIPM for a period of about one month, then for a similar period at the SMD, and finally again at the BIPM. The measurand was the 4 terminal dc resistance at low power. The BIPM was the pilot laboratory, and the comparison forms part of the ongoing BIPM key comparisons BIPM.EM-K13.a (for 1 Ω) and BIPM.EM-K13.b (for 10 kΩ). The results from the SMD and the BIPM were found to be in good agreement, with a difference smaller than the relative expanded uncertainty (95% confidence, k = 2) of 0.080 × 10-6 for 1 Ω and 0.068 × 10-6 for 10 kΩ. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Rolland, B.; Fletcher, N.; Kučera, J.; Chrobok, P.; Vo&jacute; čko&vacute; , L.
2017-01-01
This report gives the result of a bilateral comparison of resistance between the CMI (Czech Republic) and the BIPM carried out in 2015. Two 1 Ω and two 10 kΩ travelling standards belonging to the BIPM were used. The comparison was carried out with an 'A-B-A' pattern of measurements; the standards were measured first at the BIPM for a period of about one month, then for a similar period at the BIM, and finally again at the BIPM. The measurand was the 4 terminal dc resistance at low power. The BIPM was the pilot laboratory, and the comparison forms part of the ongoing BIPM key comparisons BIPM.EM-K13.a (for 1 Ω) and BIPM.EM-K13b (for 10 kΩ). The results from the CMI and the BIPM were found to be in good agreement, with a difference smaller than the relative expanded uncertainty (95% confidence, k = 2) of 0.046 × 10-6 for 1 Ω and 0.034 × 10-6 for 10 kΩ. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Rolland, B.; Fletcher, N.; Power, O.
2017-01-01
This report gives the result of a bilateral comparison of resistance between the NSAI NML (Ireland) and the BIPM carried out in 2014-2015. Two 1 Ω and two 10 kΩ travelling standards belonging to the BIPM were used. The comparison was carried out with an 'A-B-A' pattern of measurements; the standards were measured first at the BIPM for a period of about one month, then for a similar period at the NSAI-NML, and finally again at the BIPM. The measurand was the 4 terminal dc resistance at low power. The BIPM was the pilot laboratory, and the comparison forms part of the ongoing BIPM key comparisons BIPM.EM-K13.a (for 1 Ω) and BIPM.EM-K13b (for 10 kΩ). The results from the NSAI NML and the BIPM were found to be in good agreement, with a difference smaller than the relative expanded uncertainties (95% confidence, k = 2) of 0.16 × 10-6 for 1 Ω and 0.42 × 10-6 for 10 kΩ. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Power, O.; Solve, S.; Chayramy, R.; Stock, M.
2010-01-01
As a part of the ongoing BIPM key comparisons BIPM.EM-K11.a and b, a comparison of the 1.018 V and 10 V voltage reference standards of the BIPM and of the National Standards Authority of Ireland-National Metrology Laboratory (NSAI-NML), Dublin, Ireland, was carried out from March to April 2010. Two BIPM Zener diode-based travelling standards were transported by freight to NSAI-NML. At NSAI-NML, the reference standard for DC voltage is maintained at the 10 V level by means of a group of characterized Zener diode-based electronic voltage standards. The output EMF of each travelling standard, at the 10 V output terminals, was measured by direct comparison with the group standard. Measurements of the output EMF of the travelling standards at the 1.018 V output terminals were made using a potentiometer, standardized against the local 10 V reference standard. At the BIPM, the travelling standards were calibrated at both voltages before and after the measurements at NSAI-NML, using the BIPM Josephson Voltage Standard. Results of all measurements were corrected for the dependence of the output voltages on internal temperature and ambient pressure. The comparison results show that the voltage standards maintained by NSAI-NML and the BIPM were equivalent, within their stated expanded uncertainties, on the mean date of the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Rolland, B.; Fletcher, N.; Tenev, A.; Hadzhistoykova, R.
2017-01-01
This report gives the result of a bilateral comparison of resistance between the BIM (Bulgaria) and the BIPM carried out in 2013. Two 1 Ω and two 10 kΩ travelling standards belonging to the BIPM were used. The comparison was carried out with an 'A-B-A' pattern of measurements; the standards were measured first at the BIPM for a period of about one month, then for a similar period at the BIM, and finally again at the BIPM. The measurand was the 4 terminal dc resistance at low power. The BIPM was the pilot laboratory, and the comparison forms part of the ongoing BIPM key comparisons BIPM.EM-K13.a (for 1 Ω) and BIPM.EM-K13b (for 10 kΩ). The results from the BIM and the BIPM were found to be in good agreement, with a difference smaller than the relative expanded uncertainty (95% confidence, k = 2) of 0.30 × 10-6 at 10 kΩ and in reasonable agreement for 1 Ω with a relative difference of -0.18 × 10-6 with a relative expanded uncertainty of 0.17 × 10-6. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Kessler, C.; Allisy-Roberts, P. J.; Burns, D. T.; Guerra, A. S.; Laitano, R. F.; Pimpinella, M.
2010-01-01
A comparison of the standards for absorbed dose to water of the Istituto Nazionale di Metrologia delle Radiazioni Ionizzanti of the Ente per le Nuove Tecnologie, l'Energia e l'Ambiente, Italy (ENEA-INMRI), and of the Bureau International des Poids et Mesures (BIPM) has been made in 60Co gamma radiation under the auspices of the key comparison BIPM.RI(I)-K4. The comparison result, based on the calibration coefficients for three transfer standards and expressed as a ratio of the ENEA and the BIPM standards for absorbed dose to water, is 0.9999 (0.0044). The present 2007 result replaces the earlier ENEA value in this key comparison. The degrees of equivalence between the ENEA and the other participants in this comparison have been calculated and the results are given in the form of a matrix for the ten national metrology institutes (NMIs) that have published results in this ongoing comparison for absorbed dose to water. A graphical presentation is also given. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI Section I, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Solve, S.; Chayramy, R.; Power, O.; Stock, M.
2016-01-01
As part of the ongoing BIPM key comparison BIPM.EM-K11.b, a comparison of the 10 V voltage reference standards of the BIPM and the National Standards Authority of Ireland - National Metrology Laboratory (NSAI - NML), Dublin, Ireland, was carried out in January and February 2016. Two BIPM Zener diode-based travelling standards (Fluke 732B), BIPM7 (Z7) and BIPM9 (Z9), were transported by freight to NSAI-NML. At NSAI-NML, the reference standard for DC voltage at the 10 V level consists of a group of characterized Zener diode-based electronic voltage standards. The output EMF (Electromotive Force) of each travelling standard was measured by direct comparison with the group standard. At the BIPM the travelling standards were calibrated, before and after the measurements at NSAI-NML, with the Josephson Voltage Standard. Results of all measurements were corrected for the dependence of the output voltages of the Zener standards on internal temperature and ambient atmospheric pressure. The final result of the comparison is presented as the difference between the values assigned to DC voltage standards by NSAI - NML, at the level of 10 V, at NSAI - NML, UNML, and those assigned by the BIPM, at the BIPM, UBIPM, at the reference date of the 31 of January 2016. UNML - UBIPM = + 0.22 μV uc = 1.35 μV , at 10 V where uc is the combined standard uncertainty associated with the measured difference, including the uncertainty of the representation of the volt at the BIPM and at NSAI-NML, based on KJ-90, and the uncertainty related to the comparison. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Solve, S.; Chayramy, R.; Stock, M.; Vlad, D.
2015-01-01
As part of the ongoing BIPM key comparison BIPM.EM-K11.a and b, a comparison of the 1 V and 10 V voltage reference standards of the BIPM and the Service Métrologie—Metrologische Dienst (SMD), Brussel, Belgium, was carried out from October to November 2014. Two BIPM Zener diode-based travelling standards (Fluke 732B), BIPM4 (Z4) and BIPM5 (Z5), were transported by freight to SMD and also back to BIPM. At SMD, the reference standard for DC voltage is a Josephson Voltage Standard (JVS). The output EMF (Electromotive Force) of each travelling standard was measured by direct comparison with the primary standard. At the BIPM, the travelling standards were calibrated, before and after the measurements at SMD, with the Josephson Voltage Standard. Results of all measurements were corrected for the dependence of the output voltages of the Zener standards on internal temperature and ambient atmospheric pressure. The final result of the comparison is presented as the difference between the values assigned toDC voltage standards by SMD, at the level of 1.018 V and 10 V, at SMD, USMD, and those assigned by the BIPM, at the BIPM, UBIPM, at the reference date of 5 November 2014. USMD - UBIPM = 0.14 mV; uc = 0.07 mV, at 1 V USMD - UBIPM = 0.09 mV; uc = 0.49 mV , at 10 V where uc is the combined standard uncertainty associated with the measured difference, including the uncertainty of the representation of the volt at the BIPM and at SMD, based on KJ-90, and the uncertainty related to the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Solve, S.; Chayramy, R.; Stock, M.; Sengebush, F.
2015-01-01
As part of the ongoing BIPM key comparison BIPM.EM-K11.a and b, a comparison of the 1 V and 10 V voltage reference standards of the BIPM and the Justervesenet (JV), Kjeller, Norway, was carried out from January to February 2015. Two BIPM Zener diode-based travelling standards (Fluke 732B), BIPM4 (Z4) and BIPM5 (Z5), were transported by freight to JV and also back to BIPM. At JV, the reference standard for DC voltage is a Josephson Voltage Standard. The output EMF (Electromotive Force) of each travelling standard was measured by direct comparison with the primary standard. At the BIPM, the travelling standards were calibrated, before and after the measurements at JV, withthe Josephson Voltage Standard. Results of all measurements were corrected for the dependence of the output voltages of the Zener standards on internal temperature and ambient atmospheric pressure. The final result of the comparison is presented as the difference between the values assigned toDC voltage standards by JV, at the level of 1.018 V and 10 V, at JV, UJV, and those assigned by the BIPM, at the BIPM, UBIPM, at the reference date of 28 January 2015. UJV - UBIPM = 0.23 μV uc = 0.03 μV , at 1 V UJV - UBIPM = 0.63 μV uc = 0.28 μV, at 10 V where uc is the combined standard uncertainty associated with the measured difference, including the uncertainty of the representation of the volt at the BIPM and at JV, based on KJ-90, and the uncertainty related to the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Solve, S.; Chayramy, R.; Stock, M.; Power, O.
2015-01-01
As part of the ongoing BIPM key comparison BIPM.EM-K11.b, a comparison of the 10 V voltage reference standards of the BIPM and the National Standards Authority of Ireland - National Metrology Laboratory (NSAI - NML), Dublin, Ireland, was carried out in February and March 2015. Two BIPM Zener diode-based travelling standards (Fluke 732B), BIPM6 (Z6) and BIPMC (ZC), were transported by freight to NSAI-NML. At NSAI-NML, the reference standard for DC voltage at the 10 V level consists of a group of characterized Zener diode-based electronic voltage standards. The output EMF (Electromotive Force) of each travelling standard was measured by direct comparison with the group standard. At the BIPM the travelling standards were calibrated, before and after the measurements at NSAI-NML, with the Josephson Voltage Standard. Results of all measurements were corrected for the dependence of the output voltages of the Zener standards on internal temperature and ambient atmospheric pressure. The final resultof the comparison is presented as the difference between the values assigned to DC voltage standards by NSAI - NML, at the level of 10 V,at NSAI - NML, UNML, and those assigned by the BIPM, at the BIPM, UBIPM, at the reference date of 24 February 2015. UNML - UBIPM = - 0.82 mV; uc = 1.35 mV , at 10 V where uc is the combined standard uncertainty associated with the measured difference, including the uncertainty of the representation of the volt at the BIPM and at NSAI-NML, based on KJ-90, and the uncertainty related to the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Solve, S.; Chayramy, R.; Stock, M.; Pimsut, S.
2015-01-01
As part of the ongoing BIPM key comparison BIPM.EM-K11.a and b, a comparison of the 1 V and 10 V voltage reference standards of the BIPM and the National Institute of Metrology (Thailand), NIMT, was carried out from October to December 2014. Two BIPM Zener diode-based travelling standards (Fluke 732B), BIPMA (ZA) and BIPM6 (Z6), were transported by freight to NIMT and back to BIPM. At NIMT, the reference standard for DC voltage is a Josephson Voltage Standard. The output EMF (Electromotive Force) of each travelling standard was measured by direct comparison with the primary standard. At the BIPM, the travelling standards were calibrated, before and after the measurements at NIMT, with the Josephson Voltage Standard. Results of all measurements were corrected for the dependence of the output voltages of the Zener standards on internal temperature and ambient atmospheric pressure. The final result of the comparison is presented as the difference between the values assigned toDC voltage standards by NIMT, at the level of 1.018 V and 10 V, at NIMT, UNIMT, and those assigned by the BIPM, at the BIPM, UBIPM, at the reference date of 23 November 2014. UNIMT - UBIPM = 0.16 mV; uc = 0.14 mV, at 1 V UNIMT - UBIPM = - 0.03 mV; uc = 0.11 mV, at 10 V where uc is the combined standard uncertainty associated with the measured difference, including the uncertainty of the representation of the volt at the BIPM and at NIMT, based on KJ-90, and the uncertainty related to the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Solve, S.; Chayramy, R.; Stock, M.; Simionescu, M.; Cîrneanu, L.
2014-01-01
As part of the ongoing BIPM key comparison BIPM.EM-K11.a and b, a comparison of the 1 V and 10 V voltage reference standards of the BIPM and the Institut National de Metrologie (INM), Bucharest, Romania, was carried out from August to October 2013. Two BIPM Zener diode-based travelling standards (Fluke 732B), BIPM_7 (Z7) and BIPM_8 (Z8), were transported by freight to INM. At INM, the reference standard for DC voltage is a Josephson Voltage Standard. The output EMF (electromotive force) of each travelling standard was measured by direct comparison with the primary standard. At the BIPM, the travelling standards were calibrated, before and after the measurements at INM, with the Josephson Voltage Standard. Results of all measurements were corrected for the dependence of the output voltages of the Zener standards on internal temperature and ambient atmospheric pressure. The final result of the comparison is presented as the difference between the values assigned to DC voltage standards by INM, at the level of 1.018 V and 10 V, at INM, UINM, and those assigned by the BIPM, at the BIPM, UBIPM, at the reference date of 6 September 2013. UINM - UBIPM = -0.014 µV uc = 0.051 µV, at 1 V UINM - UBIPM = -0.43 µV uc = 0.34 µV, at 10 V where uc is the combined standard uncertainty associated with the measured difference, including the uncertainty of the representation of the volt at the BIPM and at INM, based on KJ-90, and the uncertainty related to the comparison. These are satisfactory results. The comparison results show that the voltage standards maintained by INM and the BIPM were equivalent, within the comparison uncertainty, on the mean date of the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Power, O.; Chayramy, R.; Solve, S.; Stock, M.
2014-01-01
As part of the ongoing BIPM key comparison BIPM.EM-K11.b, a comparison of the 10 V voltage reference standards of the BIPM and the National Standards Authority of Ireland-National Metrology Laboratory (NSAI-NML), Dublin, Ireland, was carried out from January to February 2013. Two BIPM Zener diode-based travelling standards (Fluke 732B), BIPM_8 (Z8) and BIPM_9 (Z9), were transported by freight to NSAI-NML. At NSAI-NML, the reference standard for DC voltage at the 10 V level consists of a group of characterized Zener diode-based electronic voltage standards. The output EMF (electromotive force) of each travelling standard was measured by direct comparison with the group standard. At the BIPM the travelling standards were calibrated, before and after the measurements at NSAI-NML, with the Josephson Voltage Standard. Results of all measurements were corrected for the dependence of the output voltages of the Zener standards on internal temperature and ambient atmospheric pressure. The final result of the comparison is presented as the difference between the value assigned to DC voltage standard by NSAI-NML, at the level of 10 V, at NSAI-NML, UNML, and that assigned by the BIPM, at the BIPM, UBIPM, at the reference date of 5 February 2013. UNML - UBIPM = -0.63 µV uc = 1.31 µV, at 10 V where uc is thecombined standard uncertainty associated with the measured difference, including the uncertainty of the representation of the volt at the BIPM and at NSAI-NML,based on KJ-90, and the uncertainty related to the comparison. The comparison results show that the voltage standards maintained by NSAI-NML and the BIPM were equivalent, within their stated standard uncertainties, on the mean date of the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Solve, S.; Chayramy, R.; Stock, M.; Abdel Mageed, Hala M.; Aladdin, Omar M.; Raouf, M. Helmy A.
2015-01-01
As part of the ongoing BIPM key comparison BIPM.EM-K11.a and b, a comparison of the 1 V and 10 V voltage reference standards of the BIPM and the National Institute for Standards (NIS), Giza, Egypt, was carried out from August to September 2014. Two BIPM Zener diode-based travelling standards (Fluke 732B), BIPMB (ZB) and BIPMC (ZC), were transported as hand luggage on board an airplane to NIS and back to BIPM. At NIS, the reference standard for DC voltage is a Josephson Voltage Standard. The output EMF (Electromotive Force) of each travelling standard was measured by direct comparison with the primary standard. At the BIPM, the travelling standards were calibrated, before and after the measurements at NIS, with the Josephson Voltage Standard. Results of all measurements were corrected for the dependence of the output voltages of the Zener standards on internal temperature and ambient atmospheric pressure. The final result of the comparison is presented as the difference between the values assigned to DC voltage standards by NIS, at the level of 1.018 V and 10 V, at NIS, UNIS, and those assigned by the BIPM, at the BIPM, UBIPM, at the reference date of the 7 September 2014. UNIS - UBIPM = 0.09 µV uc = 0.08 µV, at 1 V UNIS - UBIPM = 0.22 µV uc = 0.14 µV, at 10 V where uc is the combined standard uncertainty associated with the measured difference, including the uncertainty of the representation of the volt at the BIPM and at NIS, based on KJ-90, and the uncertainty related to the comparison. This is a satisfactory result. The comparison result shows that the voltage standards maintained by NIS and the BIPM were equivalent, within their stated standard uncertainties, on the mean date of the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Solve, S.; Chayramy, R.; Power, O.; Stock, M.
2014-01-01
As part of the ongoing BIPM key comparison BIPM.EM-K11.b, a comparison of the 10 V voltage reference standards of the BIPM and the National Standards Authority of Ireland-National Metrology Laboratory (NSAI-NML), Dublin, Ireland, was carried out in February and March 2014. Two BIPM Zener diode-based travelling standards (Fluke 732B), BIPM_4 (Z4) and BIPM_5 (Z5), were transported by freight to NSAI-NML. At NSAI-NML, the reference standard for DC voltage at the 10 V level consists of a group of characterized Zener diode-based electronic voltage standards. The output EMF (Electromotive Force) of each travelling standard was measured by direct comparison with the group standard. At the BIPM the travelling standards were calibrated, before and after the measurements at NSAI-NML, with the Josephson Voltage Standard. Results of all measurements were corrected for the dependence of the output voltages of the Zener standards on internal temperature and ambient atmospheric pressure. The final result of the comparison is presented as the difference between the value assigned to DC voltage standard by NSAI-NML, at the level of 10 V, at NSAI-NML, UNML, and that assigned by the BIPM, at the BIPM, UBIPM, at the reference date of 10 March 2014. UNML - UBIPM = -0.64 µV uc = 1.35 µV, at 10 V where uc is thecombined standard uncertainty associated with the measured difference, including the uncertainty of the representation of the volt at the BIPM and at NSAI-NML,based on KJ-90, and the uncertainty related to the comparison. The comparison results show that the voltage standards maintained by NSAI-NML and the BIPM were equivalent, within their stated standard uncertainties, on the mean date of the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Michotte, C.; Ratel, G.; Moune, M.; Bobin, C.
2011-01-01
In 2007, the Laboratoire national de métrologie et d'essais-Laboratoire national Henri Becquerel (LNE-LNHB), France submitted a sample of known activity of 124Sb to the International Reference System (SIR) for activity comparison at the Bureau International des Poids et Mesures (BIPM). The activity was about 5.3 MBq. The key comparison reference value (KCRV) has been recalculated to include this new value and the degrees of equivalence between each equivalent activity for the three participants measured in the SIR and the KCRV are presented in a table and graphically. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI Section II, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
ERIC Educational Resources Information Center
Johnson, Clarence; Kritsonis, William Allan
2007-01-01
This article addresses several key ongoing issues in a large urban school district. Literature focuses on what make a large urban school district effective in Human Resource Management. The effectiveness is addressed through recruitment and retention practices. A comparison of the school district with current research is the main approach to the…
NASA Astrophysics Data System (ADS)
Power, O.; Solve, S.; Chayramy, R.; Stock, M.
2012-01-01
As part of the on-going BIPM key comparison BIPM.EM-K11.b, a comparison of the 10 V voltage reference standards of the BIPM and the National Standards Authority of Ireland-National Metrology Laboratory (NSAI-NML), Dublin, Ireland, was carried out from February to March 2012. Two BIPM Zener diode-based travelling standards (Fluke 732B), BIPM_C (ZC) and BIPM_D (ZD), were transported by freight to NSAI-NML. At NSAI-NML, the reference standard for DC voltage at the 10 V level consists of a group of characterized Zener diode-based electronic voltage standards. The output EMF (electromotive force) of each travelling standard was measured by direct comparison with the group standard. At the BIPM the travelling standards were calibrated, before and after the measurements at NSAI-NML, with the Josephson voltage standard. Results of all measurements were corrected for the dependence of the output voltages on internal temperature and ambient atmospheric pressure. The final result of the comparison is presented as the difference between the value assigned to DC voltage standard by NSAI-NML, at the level of 10 V, at NSAI-NML, UNML, and that assigned by the BIPM, at the BIPM, UBIPM, at the reference date of 23 February 2012. UNML - UBIPM = +0.83 µV, uc = 1.35 µV, at 10 V where uc is the combined standard uncertainty associated with the measured difference, including the uncertainty of the representation of the volt at the BIPM and at NSAI-NML, based on KJ-90, and the uncertainty related to the comparison. The final result is impacted by the anomalous offset between the NSAI-NML results for the two transfer standards. The reason for this offset hasn't been determined. However, the difference remains within the total combined standard uncertainty. Therefore, the comparison result shows that the voltage standards maintained by NSAI-NML and the BIPM were equivalent, within their stated expanded uncertainties, on the mean date of the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Gournay, Pierre; Rolland, Benjamin; Mortara, Alessandro; Jeanneret, Blaise
2018-01-01
An on-site comparison of the quantum Hall effect (QHE) resistance standards of the Federal Institute of Metrology METAS (Switzerland) and of the Bureau International des Poids et Mesures (BIPM) was made in December 2017. Measurements of a 100 Ω standard in terms of the conventional value of the von Klitzing constant, RK-90, agreed to 5 parts in 1010 with a relative combined standard uncertainty uc = 23 × 10‑10. Scaling from 100 Ω to 10 kΩ has also been addressed through the measurement of a 10000 Ω/100 Ω ratio. The measurements carried out agreed to 2 parts in 1010 with a relative combined standard uncertainty uc = 19 × 10‑10. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Solve, S.; Chayramy, R.; Matlejoane, A. M.; Magagula, L.; Stock, M.
2018-01-01
As part of the ongoing BIPM key comparison BIPM.EM-K11.a and b, a comparison of the 1.018 V and 10 V voltage reference standards of the BIPM and the National Metrology Institute of South Africa, NMISA (South Africa), was carried out from April to June 2017. Two BIPM Zener diode-based travelling standards (Fluke 732B), BIPMA (ZA) and BIPMB (ZB), were transported by freight to NMISA and back to BIPM. In order to keep the Zeners powered during their transportation phase, a voltage stabilizer developed by BIPM was connected in parallel to the internal battery. It consists of a set of two batteries, electrically protected from surcharge-discharge, easy to recharge and is designed to power two transfer standards for ten consecutive days. At NMISA, the reference standard for DC voltage is a Josephson Voltage Standard. The output EMF (Electromotive Force) of each travelling standard was measured by direct comparison with the primary standard. At the BIPM, the travelling standards were calibrated, before and after the measurements at NMISA, with the Josephson Voltage Standard. Results of all measurements were corrected for the dependence of the output voltages of the Zener standards on internal temperature and atmospheric pressure. The final result of the comparison is presented as the difference between the values assigned to DC voltage standards by NMISA, at the level of 1.018 V and 10 V, at NMISA, UNMISA, and those assigned by the BIPM, at the BIPM, UBIPM, at the reference dates of the 19th and 18th of May 2017, respectively. UNMISA - UBIPM = + 0.07 μV uc = 0.02 μV, at 1.018 V UNMISA - UBIPM = + 0.001 μV uc = 0.34 μV, at 10 V where uc is the combined standard uncertainty associated with the measured difference, including the uncertainty of the representation of the volt at the BIPM and at NMISA, based on KJ-90, and the uncertainty related to the comparison. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Solve, S.; Chayramy, R.; Ben Salah, B.; Mallat, A.; Abene, L.; Stock, M.
2016-01-01
As part of the ongoing BIPM key comparison BIPM.EM-K11.a and b, a comparison of the 1 V and 10 V voltage reference standards of the BIPM and the Laboratoire de Métrologie Electrique, DEFNAT (Tunisia), was carried out from February to March 2016. Two BIPM Zener diode-based travelling standards (Fluke 732B), BIPMC (ZC) and BIPM6 (Z6), were transported by freight to DEFNAT and back to BIPM. In order to keep the Zeners powered during their transportation phase, a BIPM in-house voltage stabiliser was connected in parallel to the internal battery. The voltage stabiliser consists of a set of two batteries, electrically protected from surcharge-discharge, easy to recharge and is designed to power two transfer standards for 10 consecutive days. At DEFNAT, the reference standard for DC voltage is a Josephson Voltage Standard. The output EMF (Electromotive Force) of each travelling standard was measured by direct comparison with the primary standard. At the BIPM, the travelling standards were calibrated, before and after the measurements at DEFNAT, with the Josephson Voltage Standard. Results of all measurements were corrected for the dependence of the output voltages of the Zener standards on internal temperature and ambient atmospheric pressure. The final result of the comparison is presented as the difference between the values assigned to DC voltage standards by DEFNAT, at the level of 1.018 V and 10 V, at DEFNAT, UDEFNAT, and those assigned by the BIPM, at the BIPM, UBIPM, at the reference date of the 26th of February 2016. UDEFNAT - UBIPM = + 0.07 μV uc = 0.04 μV, at 1.018 V UDEFNAT - UBIPM = + 0.38 μV uc = 0.10 μV, at 10 V where uc is the combined standard uncertainty associated with the measured difference, including the uncertainty of the representation of the volt at the BIPM and at NSAI-NML, based on KJ-90, and the uncertainty related to the comparison. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Solve, S.; Chayramy, R.; Stock, M.; Pimsut, S.; Rujirat, N.
2016-01-01
A comparison of the Josephson array voltage standards of the Bureau International des Poids et Mesures (BIPM) and the National Institute of Metrology - (Thailand), NIMT, was carried out in November 2015 at the level of 10 V. For this exercise, options A and B of the BIPM.EM-K10.b comparison protocol were applied. Option B required the BIPM to provide a reference voltage for measurement by the NIMT using its Josephson standard with its own measuring device. Option A required the NIMT to provide a reference voltage with its Josephson voltage standard for measurement by the BIPM using an analogue nanovoltmeter and associated measurement loop. In all cases the BIPM array was kept floating from ground. The final results were in good agreement within the combined relative standard uncertainty of 2.6 parts in 1010 for the nominal voltage of 10 V. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Solve, S.; Chayramy, R.; Stock, M.; Pantelic-Babic, J.; Sofranac, Z.; Zivkovic, V.
2015-01-01
As part of the ongoing BIPM key comparison BIPM.EM-K11.a and b, a comparison of the 1 V and 10 V voltage reference standards of the BIPM and the Directorate of Measures and Precious Metals (DMDM), Beograd, Serbia, was carried out from January to March 2014. Two BIPM Zener diode-based travelling standards (Fluke 732B), BIPM6 (Z6) and BIPMA (ZA), were transported by freight to DMDM. At DMDM, the reference standard for DC voltage is a Josephson Voltage Standard. The output electromotive force of each travelling standard was measured by direct comparison with the primary standard. At the BIPM, the travelling standards were calibrated, before and after the measurements at DMDM, with the Josephson Voltage Standard. Results of all measurements were corrected for the dependence of the output voltages of the Zener standards on internal temperature and ambient atmospheric pressure. The final result of the comparison is presented as the difference between the values assigned to DC voltage standards by DMDM, at the level of 1.018 V and 10 V, at DMDM, UDMDM, and those assigned by the BIPM, at the BIPM, UBIPM, at the reference date of the 13 February 2014. UDMDM - UBIPM = 0.094 µV uc = 0.072 µV, at 1 V UDMDM - UBIPM = 0.39 µV uc = 0.12 µV, at 10 V where uc is the combined standard uncertainty associated with the measured difference, including the uncertainty of the representation of the volt at the BIPM and at DMDM, based on KJ-90, and the uncertainty related to the comparison. The results at the 10 V level are not covered by the uncertainties with a coverage factor of 2. After the distribution of the Draft A, the DMDM discovered that the pressure gauge was defective. Some considerations on the correction to apply on the comparison result and the corresponding uncertainties are presented in the report. Nevertheless, the above results fully cover the CMCs of DMDM which are significantly larger. No corrections for temperature and pressure are applied in calibrations for customers' secondary standards. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Picard, S.; Burns, D. T.; Roger, P.; de Prez, L. A.; Jansen, B. J.; Pooter, J. A.
2017-01-01
A comparison of the dosimetry for accelerator photon beams was carried out between the Dutch Metrology Institute (VSL) and the Bureau International des Poids et Mesures (BIPM) from 23 September to 20 October 2014. The comparison was based on the determination of absorbed dose to water for three radiation qualities of the medical accelerator facilities of the National Physical Laboratory (United Kingdom). After establishing Draft B, the VSL discovered an error in the calculation of the correction factor for excess-heat linked to the VSL glass vessel used in the measurements at the NPL. The comparison results for the revised standard, reported as ratios of the VSL and the BIPM evaluations (and with the combined standard uncertainties given in parentheses), are 0.9959 (54) at 6 MV, 0.9958 (64) at 10 MV and 0.9991 (75) at 25 MV. This result is part of the on-going BIPM.RI(I)-K6 series of comparisons. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Gournay, Pierre; Rolland, Benjamin; Kučera, Jan; Vojáčková, Lucie
2017-01-01
An on-site comparison of the quantum Hall effect (QHE) resistance standards of the Czech Metrology Institute (CMI) and of the Bureau International des Poids et Mesures (BIPM) was made in April 2017. Measurements of a 100 Ω standard in terms of the conventional value of the von Klitzing constant, RK-90, agreed to 6 parts in 1010 with a relative combined standard uncertainty uc = 25 × 10-10. Measurements of 10000 Ω/100 Ω and 100 Ω/1 Ω ratios agreed to 11 parts in 1010 with uc = 22 × 10-10 and to 33 parts in 1010 with uc = 32 × 10-10, respectively. The influence of the current reversal time has been systematically investigated in order to take into account possible errors due to the Peltier effect, which may be particularly large in 1 Ω standards. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Solve, S.; Chayramy, R.; Stock, M.; Pantelic-Babic, J.; Sofranac, Z.; Cincar Vujovic, T.
2016-01-01
A comparison of the Josephson array voltage standards of the Bureau International des Poids et Mesures (BIPM) and the Directorate of Measures and Precious Metals (DMDM), Belgrade, Serbia, was carried out in June 2015 at the level of 10 V. For this exercise, options A and B of the BIPM.EM-K10.b comparison protocol were applied. Option B required the BIPM to provide a reference voltage for measurement by the DMDM using its Josephson standard with its own measuring device. Option A required the DMDM to provide a reference voltage with its Josephson voltage standard for measurement by the BIPM using an analogue nanovoltmeter and associated measurement loop. Since no sufficiently stable voltage could be achieved in this configuration, a digital detector was used. In all cases the BIPM array was kept floating from ground. The final results were in good agreement within the combined relative standard uncertainty of 1.5 parts in 1010 for the nominal voltage of 10 V. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Clinical and Functional Outcome of Childhood ADHD 33 Years Later
Klein, Rachel G.; Mannuzza, Salvatore; Ramos Olazagasti, María A.; Roizen Belsky, Erica; Hutchison, Jesse A.; Lashua-Shriftman, Erin; Castellanos, F. Xavier
2012-01-01
Context Prospective studies of childhood attention deficit/hyperactivity disorder (ADHD) have not extended beyond early adulthood. Objective To test whether children diagnosed with ADHD at mean age 8 (probands) have worse educational, occupational, economic, social, marital outcomes; higher rates of ongoing ADHD, antisocial personality disorder (ASPD), substance disorders (SD); adult onset psychiatric disorders, psychiatric hospitalizations and incarcerations, than non-ADHD comparisons, at mean age 41. To test for: positive associations between probands’ ongoing ADHD and ASPD, and SD’s; and for worse social and occupational functioning in probands without ongoing psychiatric disorders, than comparisons. Design Prospective, 33 year follow-up study, with blind clinical assessments. Setting Research clinic. Participants 135 Caucasian males with ADHD in childhood, free of conduct disorder, and 136 male comparisons without childhood ADHD (65% and 76% of original cohort, respectively). Main Outcome Measures Occupational, economic, and educational attainment; marital history; occupational and social functioning; ongoing and lifetime psychiatric disorders; psychiatric hospitalizations, and incarcerations. Results Probands had significantly worse educational, occupational, economic, social outcomes, and more divorces than comparisons; higher rates of ongoing ADHD (22% vs 5%, p<.001), ASPD (16% vs 0%, p<.001)and SD (14% vs 5%, p<.01), but not more mood or anxiety disorders (p’s=.36 and .33). Ongoing ADHD was weakly related to ongoing SD (phi=.19, p=.04), and ASPD+SD (phi=.20, p=.04). Lifetime, probands had significantly more ASPD and SD’s, but not mood or anxiety disorders, and more psychiatric hospitalizations and incarcerations than comparisons. Relative to comparisons, psychiatric disorders with onsets at age 21 or beyond were not significantly elevated in probands. Probands without ongoing psychiatric disorders had worse social, but not occupational, functioning. Conclusions The multiple disadvantages predicted by childhood ADHD well into adulthood began in adolescence, without increased onsets of new disorders after age 20. Findings highlight the importance of extended monitoring and treatment of children with ADHD. PMID:23070149
NASA Astrophysics Data System (ADS)
Michotte, C.; Nonis, M.; Bergeron, D.; Cessna, J.; Fitzgerald, R.; Pibida, L.; Zimmerman, B.; Fenwick, A.; Ferreira, K.; Keightley, J.; Da Silva, I.
2017-01-01
In 2016, comparisons of activity measurements of 18F and 64Cu using the Transfer Instrument of the International Reference System (SIRTI) took place at the National Institute of Standards and Technology (NIST, USA). This is the first SIRTI comparison for 64Cu. Ampoules containing about 27 kBq of 18F and 100 kBq of 64Cu solutions were measured in the SIRTI for about 5 and 1.5 half-lives, respectively. The NIST standardized the activity in the ampoules by ionization chamber measurements traceable to 4π(LS)β-γ anticoincidence measurements. The comparisons, identifiers BIPM.RI(II)-K4.F-18 and BIPM.RI(II)-K4.Cu-64, are linked to the corresponding BIPM.RI(II)-K1.F-18 and BIPM.RI(II)-K1.Cu-64 comparisons and degrees of equivalence with the respective key comparison reference values have been evaluated. The NIST replaces its earlier degree of equivalence for 18F obtained in the frame of the CCRI(II)-K3.F-18 comparison in 2001. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Application of He ion microscopy for material analysis
NASA Astrophysics Data System (ADS)
Altmann, F.; Simon, M.; Klengel, R.
2009-05-01
Helium ion beam microscopy (HIM) is a new high resolution imaging technique. The use of Helium ions instead of electrons enables none destructive imaging combined with contrasts quite similar to that from Gallium ion beam imaging. The use of very low probe currents and the comfortable charge compensation using low energy electrons offer imaging of none conductive samples without conductive coating. An ongoing microelectronic sample with Gold/Aluminum interconnects and polymer electronic devices were chosen to evaluate HIM in comparison to scanning electron microscopy (SEM). The aim was to look for key applications of HIM in material analysis. Main focus was on complementary contrast mechanisms and imaging of none conductive samples.
Conrad, Agatha M; Lewin, Terry J; Sly, Ketrina A; Schall, Ulrich; Halpin, Sean A; Hunter, Mick; Carr, Vaughan J
2014-11-18
Despite strong research interest in psychosis risk identification and the potential for early intervention, few papers have sought to document the implementation and evaluation of specialised psychosis related services. Assessment of Ultra High Risk (UHR) has been given priority, but it is equally as important to identify appropriate comparison groups and other baseline differences. This largely descriptive service evaluation paper focuses on the 'baseline characteristics' of referred clients (i.e., previously assessed characteristics or those identified within the first two months following service presentation). Data are reported from a 10-year layered service audit of all presentations to a 'Psychological Assistance Service' for young people (PAS, Newcastle, Australia). Baseline socio-demographic and clinical characteristics (N =1,997) are described (including clients' psychosis and UHR status, previous service contacts, hospitalisation rates, and diagnostic and comorbidity profiles). Key groups are identified and comparisons made between clients who received ongoing treatment and those who were primarily assessed and referred elsewhere. Clients averaged 19.2 (SD =4.5) years of age and 59% were male. One-tenth of clients (9.6%) were categorised as UHR, among whom there were relatively high rates of attenuated psychotic symptoms (69.1%), comorbid depression (62.3%), anxiety (42.9%), and attentional and related problems (67.5%). Overall, one-fifth (19.8%) experienced a recent psychotic episode, while a further 14.5% were categorised as having an existing psychosis (46.7% with a schizophrenia diagnosis), amongst whom there were relatively high rates of comorbid substance misuse (52.9%), psychosocial (70.2%) and physical health (37.7%) problems. The largest group presenting to PAS were those with non-psychotic disorders (43.7%), who provide a valuable comparison group against which to contrast the health trajectories of those with UHR and recent psychosis. Ongoing treatment by PAS was preferentially given to those experiencing or at risk for psychosis and those reporting greater current distress or dysfunction. Whether or not UHR clients transition to psychosis, they displayed high rates of comorbid depression and anxiety at service presentation, with half receiving ongoing treatment from PAS. Although international comparisons with similar services are difficult, the socio-demographic and comorbidity patterns observed here were viewed as largely consistent with those reported elsewhere.
Space, place and (waiting) time: reflections on health policy and politics.
Sheard, Sally
2018-02-19
Health systems have repeatedly addressed concerns about efficiency and equity by employing trans-national comparisons to draw out the strengths and weaknesses of specific policy initiatives. This paper demonstrates the potential for explicit historical analysis of waiting times for hospital treatment to add value to spatial comparative methodologies. Waiting times and the size of the lists of waiting patients have become key operational indicators. In the United Kingdom, as National Health Service (NHS) financial pressures intensified from the 1970s, waiting times have become a topic for regular public and political debate. Various explanations for waiting times include the following: hospital consultants manipulate NHS waiting lists to maintain their private practice; there is under-investment in the NHS; and available (and adequate) resources are being used inefficiently. Other countries have also experienced ongoing tensions between the public and private delivery of universal health care in which national and trans-national comparisons of waiting times have been regularly used. The paper discusses the development of key UK policies, and provides a limited Canadian comparative perspective, to explore wider issues, including whether 'waiting crises' were consciously used by policymakers, especially those brought into government to implement new economic and managerial strategies, to diminish the autonomy and authority of the medical professional in the hospital environment.
Focus on Alectinib and Competitor Compounds for Second-Line Therapy in ALK-Rearranged NSCLC
Tran, Phu N.; Klempner, Samuel J.
2016-01-01
The management of anaplastic lymphoma kinase rearranged (ALK+) non-small cell lung cancer (NSCLC) exemplifies the potential of a precision medicine approach to cancer care. The ALK inhibitor crizotinib has led to improved outcomes in the first- and second-line setting; however, toxicities, intracranial activity, and acquired resistance necessitated the advent of later generation ALK inhibitors. A large portion of acquired resistance to ALK inhibitors is caused by secondary mutations in the ALK kinase domain. Alectinib is a second-generation ALK inhibitor capable of overcoming multiple crizotinib-resistant ALK mutations and has demonstrated improved outcomes after crizotinib failure. Favorable toxicity profile and improved intracranial activity have spurred ongoing front-line trials and comparisons to other ALK inhibitors. However, important questions regarding comparability to competitor compounds, acquired alectinib resistance, and ALK inhibitor sequencing remain. Here, we review the key clinical data supporting alectinib in the second-line therapy of ALK+ NSCLC and provide context in comparison to other ALK inhibitors in development. PMID:27965961
Focus on Alectinib and Competitor Compounds for Second-Line Therapy in ALK-Rearranged NSCLC.
Tran, Phu N; Klempner, Samuel J
2016-01-01
The management of anaplastic lymphoma kinase rearranged (ALK+) non-small cell lung cancer (NSCLC) exemplifies the potential of a precision medicine approach to cancer care. The ALK inhibitor crizotinib has led to improved outcomes in the first- and second-line setting; however, toxicities, intracranial activity, and acquired resistance necessitated the advent of later generation ALK inhibitors. A large portion of acquired resistance to ALK inhibitors is caused by secondary mutations in the ALK kinase domain. Alectinib is a second-generation ALK inhibitor capable of overcoming multiple crizotinib-resistant ALK mutations and has demonstrated improved outcomes after crizotinib failure. Favorable toxicity profile and improved intracranial activity have spurred ongoing front-line trials and comparisons to other ALK inhibitors. However, important questions regarding comparability to competitor compounds, acquired alectinib resistance, and ALK inhibitor sequencing remain. Here, we review the key clinical data supporting alectinib in the second-line therapy of ALK+ NSCLC and provide context in comparison to other ALK inhibitors in development.
Current Challenges for HTCMC Aero-Propulsion Components
NASA Technical Reports Server (NTRS)
DiCarlo, James A.; Bansal, Narottam P.
2007-01-01
In comparison to the best metallic materials, HTCMC aero-propulsion engine components offer the opportunity of reduced weight and higher temperature operation, with corresponding improvements in engine cooling requirements, emissions, thrust, and specific fuel consumption. Although much progress has been made in the development of advanced HTCMC constituent materials and processes, major challenges still remain for their implementation into these components. The objectives of this presentation are to briefly review (1) potential HTCMC aero-propulsion components and their generic material performance requirements, (2) recent progress at NASA and elsewhere concerning advanced constituents and processes for meeting these requirements, (3) key HTCMC component implementation challenges that are currently being encountered, and (4) on-going activities within the new NASA Fundamental Aeronautics Program that are addressing these challenges.
Designing an activity-based costing model for a non-admitted prisoner healthcare setting.
Cai, Xiao; Moore, Elizabeth; McNamara, Martin
2013-09-01
To design and deliver an activity-based costing model within a non-admitted prisoner healthcare setting. Key phases from the NSW Health clinical redesign methodology were utilised: diagnostic, solution design and implementation. The diagnostic phase utilised a range of strategies to identify issues requiring attention in the development of the costing model. The solution design phase conceptualised distinct 'building blocks' of activity and cost based on the speciality of clinicians providing care. These building blocks enabled the classification of activity and comparisons of costs between similar facilities. The implementation phase validated the model. The project generated an activity-based costing model based on actual activity performed, gained acceptability among clinicians and managers, and provided the basis for ongoing efficiency and benchmarking efforts.
Silove, D M; Tay, A K; Tol, W A; Tam, N; Dos Reis, N; da Costa, Z; Soares, C; Rees, S
2016-11-15
Adult separation anxiety (ASA) symptoms are prevalent amongst young women in low and middle-income countries and symptoms may be common in pregnancy. No studies have focused on defining distinctive patterns of ASA symptoms amongst pregnant women in these settings or possible associations with trauma exposure and ongoing stressors. In a consecutive sample of 1672 women attending antenatal clinics in Dili, Timor-Leste (96% response), we assessed traumatic events of conflict, ongoing adversity, intimate partner violence (IPV), ASA, post-traumatic stress disorder (PTSD) and severe psychological distress. Latent Class Analysis was used to identify classes of women based on their distinctive profiles of ASA symptoms, comparisons then being made with key covariates including trauma domains of conflict, intimate partner violence (IPV) and ongoing stressors. LCA yielded three classes, comprising a core ASA (4%), a limited ASA (25%) and a low symptom class (61%). The core ASA class reported exposure to multiple traumatic losses and IPV and showed a pattern of comorbidity with PTSD; the limited ASA class predominantly reported exposure to ongoing stressors and was comorbid with severe psychological distress; the low symptom class reported relatively low levels of exposure to trauma and stressors. The study is cross-sectional, cautioning against inferring causal inferences. The core ASA group may be in need of immediate intervention given the high rate of exposure to IPV amongst this class. A larger number of women experiencing a limited array of non-specific ASA symptoms may need assistance to address the immediate stressors of pregnancy. Copyright © 2016 Elsevier B.V. All rights reserved.
Cost analysis of open radical cystectomy versus robot-assisted radical cystectomy.
Bansal, Sukhchain S; Dogra, Tara; Smith, Peter W; Amran, Maisarah; Auluck, Ishna; Bhambra, Maninder; Sura, Manraj S; Rowe, Edward; Koupparis, Anthony
2018-03-01
To perform a cost analysis comparing the cost of robot-assisted radical cystectomy (RARC) with open RC (ORC) in a UK tertiary referral centre and to identify the key cost drivers. Data on hospital length of stay (LOS), operative time (OT), transfusion rate, and volume and complication rate were obtained from a prospectively updated institutional database for patients undergoing RARC or ORC. A cost decision tree model was created. Sensitivity analysis was performed to find key drivers of overall cost and to find breakeven points with ORC. Monte Carlo analysis was performed to quantify the variability in the dataset. One RARC procedure costs £12 449.87, or £12 106.12 if the robot was donated via charitable funds. In comparison, one ORC procedure costs £10 474.54. RARC is 18.9% more expensive than ORC. The key cost drivers were OT, LOS, and the number of cases performed per annum. High ongoing equipment costs remain a large barrier to the cost of RARC falling. However, minimal improvements in patient quality of life would be required to offset this difference. © 2017 The Authors BJU International © 2017 BJU International Published by John Wiley & Sons Ltd.
Contribution of Temperature and Precipitation Anomalies to the Ongoing California Drought
NASA Astrophysics Data System (ADS)
Luo, L.; Apps, D.; Arcand, S. E.
2015-12-01
The ongoing multiyear drought over California is a major concern for the residents of the golden state as it brings water restrictions in preparing for water shortages and wild fires due to dry and hot conditions. Both positive temperature and negative precipitation anomalies can contribute to drought developments, but how important are these anomalies for the ongoing California drought? Using the VIC hydrological model, this study investigated the relative contribution of temperature and precipitation anomalies to the ongoing 2011-2015 drought in comparison with another multiyear drought between 1987 and 1992 over the same region. By swapping the observed temperature and precipitation anomalies between two drought events, the study was able to show how temperature and precipitation anomalies and their spatial variability affect other elements of the hydrological cycle including evapotranspiration, soil moisture and streamflow, thus the severity of the drought. The comparison between these two events helps to reveal the unique characteristics of the current drought and provides useful insights for drought prediction and mitigation.
The protostar OMC-2 FIR 4: Results from the CHESS Herschel/HIFI spectral survey
NASA Astrophysics Data System (ADS)
Kama, Mihkel; Lopez-Sepulcre, Ana; Ceccarelli, Cecilia; Dominik, Carsten; Caux, Emmanuel; Fuente, Asuncion
2013-07-01
The intermediate-mass protostar OMC-2 FIR 4 in Orion is the focus of several ongoing studies, including a CHESS key programme Herschel/HIFI spectral survey. In this poster, we review recent CHESS results on this source, including the properties of the central hot core, the presence of a compact outflow, the spatial variation of the chemical composition, and the discovery of a tenuous foreground cloud. The HIFI spectrum of FIR 4 contains 719 lines from 40 species and isotopologs. Cooling by lines detectable with our sensitivity contributes 2% of the total in the 480 to 1900 GHz range. The total line flux is dominated by CO, followed by H2O and CH3OH. Initial comparisons with spectral surveys of other sources will also be presented.
Liang, Lin-Fu; Chen, Wen-Ting; Mollo, Ernesto; Yao, Li-Gong; Wang, He-Yao; Xiao, Wei; Guo, Yue-Wei
2017-06-01
Minor metabolic components, six new cembranoids sarcophytrols G - L (1 - 6) along with two known related analogues 7 and 8, were isolated from the South China Sea soft coral Sarcophyton trocheliophorum. Their structures were elucidated by extensive spectroscopic analyses (1D-, 2D-NMR, and ESI-MS) as well as comparison with literature data. As part of our ongoing research project for discovering bioactive substances from Chinese marine invertebrates, compounds 1 - 8 were tested for their inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), a key target for the treatment of Type-II diabetes and obesity. However, none of them exhibited potent PTP1B inhibitory activities. © 2017 Wiley-VHCA AG, Zurich, Switzerland.
America's Children: Key National Indicators of Well-Being, 2011
ERIC Educational Resources Information Center
Cook, Traci; Blachman, Dara; Dye, Jane; Macartney, Suzanne; Lukacs, Susan; Howie, LaJeana; Kena, Grace; Sonnenberg, William; Axelrad, Daniel; Steffen, Barry; Truman, Jennifer; Cotto, Jessica; Jekielek, Susan; Mueggenborg, Mary; Coleman-Jensen, Alisha; Denton, Stephanie; Avenevoli, Shelli; Singleton, James; Knighton, Cindi; Han, Beth; O'Connell, Kellie; Guenther, Patricia; Hiza, Hazel; Kuczynski, Kevin; Koegel, Kristin; Radel, Laura
2011-01-01
"America's Children: Key National Indicators of Well-Being, 2011" is a compendium of indicators depicting both the promises and the challenges confronting our Nation's young people. The report, the 15th in an ongoing series, presents 41 key indicators on important aspects of children's lives. These indicators are drawn from the most…
NASA Astrophysics Data System (ADS)
Dutton, Gregory
Forensic science is a collection of applied disciplines that draws from all branches of science. A key question in forensic analysis is: to what degree do a piece of evidence and a known reference sample share characteristics? Quantification of similarity, estimation of uncertainty, and determination of relevant population statistics are of current concern. A 2016 PCAST report questioned the foundational validity and the validity in practice of several forensic disciplines, including latent fingerprints, firearms comparisons and DNA mixture interpretation. One recommendation was the advancement of objective, automated comparison methods based on image analysis and machine learning. These concerns parallel the National Institute of Justice's ongoing R&D investments in applied chemistry, biology and physics. NIJ maintains a funding program spanning fundamental research with potential for forensic application to the validation of novel instruments and methods. Since 2009, NIJ has funded over 179M in external research to support the advancement of accuracy, validity and efficiency in the forensic sciences. An overview of NIJ's programs will be presented, with examples of relevant projects from fluid dynamics, 3D imaging, acoustics, and materials science.
Towards an International Classification for Patient Safety: key concepts and terms
Runciman, William; Hibbert, Peter; Thomson, Richard; Van Der Schaaf, Tjerk; Sherman, Heather; Lewalle, Pierre
2009-01-01
Background Understanding the patient safety literature has been compromised by the inconsistent use of language. Objectives To identify key concepts of relevance to the International Patient Safety Classification (ICPS) proposed by the World Alliance For Patient Safety of the World Health Organization (WHO), and agree on definitions and preferred terms. Methods Six principles were agreed upon—that the concepts and terms should: be applicable across the full spectrum of healthcare; be consistent with concepts from other WHO Classifications; have meanings as close as possible to those in colloquial use; convey the appropriate meanings with respect to patient safety; be brief and clear, without unnecessary or redundant qualifiers; be fit-for-purpose for the ICPS. Results Definitions and preferred terms were agreed for 48 concepts of relevance to the ICPS; these were described and the relationships between them and the ICPS were outlined. Conclusions The consistent use of key concepts, definitions and preferred terms should pave the way for better understanding, for comparisons between facilities and jurisdictions, and for trends to be tracked over time. Changes and improvements, translation into other languages and alignment with other sets of patient safety definitions will be necessary. This work represents the start of an ongoing process of progressively improving a common international understanding of terms and concepts relevant to patient safety. PMID:19147597
Koh, Eun; Choi, Ga-Young; Cho, Ji Young
2016-02-01
The study evaluates the effectiveness of an ongoing, community-based breast cancer prevention program offered by a local social services agency in the Washington, DC, metropolitan area. Korean American women who participated in this breast cancer prevention program were compared with those who did not participate in their knowledge, attitude, and screening behaviors. The study found that the intervention group was more knowledgeable on breast cancer and related services and reported more positive attitudes toward breast cancer screening services than the comparison group. The participants in the intervention group were also more likely to plan to receive a mammogram than those in the comparison group. However, significant differences were not observed in the two groups in their intention to receive a clinical breast examination. The study findings suggest that an ongoing, community-based breast cancer prevention program can be an effective method of addressing breast cancer prevention disparities observed among Korean American women.
Real-space observation of strong metal-support interaction: state-of-the-art and what's the next.
Shi, X Y; Zhang, W; Zhang, C; Zheng, W T; Chen, H; Qi, J G
2016-06-01
The real-space resolving of the encapsulated overlayer in the well-known model and industry catalysts, ascribed to the advent of dedicated transmission electron microscopy, enables us to probe novel nano/micro architecture chemistry for better application, revisiting our understanding of this key issue in heterogeneous catalysis. In this review, we summarize the latest progress of real-space observation of SMSI in several well-known systems mainly covered from the metal catalysts (mostly Pt) supported by the TiO2 , CeO2 and Fe3 O4 . As a comparison with the model catalyst Pt/Fe3 O4 , the industrial catalyst Cu/ZnO is also listed, followed with the suggested ongoing directions in the field. © 2015 The Authors Journal of Microscopy © 2015 Royal Microscopical Society.
NASA Astrophysics Data System (ADS)
van der Veen, A. M. H.; Nieuwenkamp, G.; Oudwater, R.; Wessel, R. M.; Novak, J.; Perrochet, J.-F.; Ackermann, A.; Rakowska, A.; Cortez, L.; Dias, F.; Konopelko, L.; Kustikov, Y.; Sutour, C.; Masé, T.; Milton, M. J. T.; Uprichard, I. J.; Woods, P. T.; Walden, J.; Lopez Esteban, M. T.
2005-01-01
Following-up the key comparison CCQM-K1c, EUROMET organized a regional key comparison involving ten laboratories. The objectives of this EUROMET key comparison were essentially the same as for the CCQM-K1c comparison: to compare the measurement capabilities of national metrological institutes (NMIs) in measuring amount of substance fractions of nitrogen monoxide in nitrogen. The nominal amount of substance fraction of the standards used for the comparison was 100 µmol/mol. The pilot laboratory in this key comparison also piloted the CCQM key comparison and has long-term experience in the behaviour of these mixtures and the technical challenges in preparing batches of very similar mixtures. Most participants used chemiluminescence as the measurement method; two participants used UV techniques and one ND-IR. The degrees of equivalence between this comparison and CCQM-K1c were calculated; four laboratories participated in both key comparisons, thus providing sufficient data for demonstrating the comparability. Main text. To reach the main text of this paper, click on Final Report. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the Mutual Recognition Arrangement (MRA).
20 CFR 404.1519s - Authorizing and monitoring the consultative examination.
Code of Federal Regulations, 2011 CFR
2011-04-01
... evaluating claimant reactions to key providers; and (11) A program of systematic, onsite reviews of key...) A process for orientation, training, and review of new consultative examination providers, with....1519m. (7) Procedures for the ongoing review of consultative examination results to ensure compliance...
The longevity of lava dome eruptions
NASA Astrophysics Data System (ADS)
Wolpert, Robert L.; Ogburn, Sarah E.; Calder, Eliza S.
2016-02-01
Understanding the duration of past, ongoing, and future volcanic eruptions is an important scientific goal and a key societal need. We present a new methodology for forecasting the duration of ongoing and future lava dome eruptions based on a database (DomeHaz) recently compiled by the authors. The database includes duration and composition for 177 such eruptions, with "eruption" defined as the period encompassing individual episodes of dome growth along with associated quiescent periods during which extrusion pauses but unrest continues. In a key finding, we show that probability distributions for dome eruption durations are both heavy tailed and composition dependent. We construct objective Bayesian statistical models featuring heavy-tailed Generalized Pareto distributions with composition-specific parameters to make forecasts about the durations of new and ongoing eruptions that depend on both eruption duration to date and composition. Our Bayesian predictive distributions reflect both uncertainty about model parameter values (epistemic uncertainty) and the natural variability of the geologic processes (aleatoric uncertainty). The results are illustrated by presenting likely trajectories for 14 dome-building eruptions ongoing in 2015. Full representation of the uncertainty is presented for two key eruptions, Soufriére Hills Volcano in Montserrat (10-139 years, median 35 years) and Sinabung, Indonesia (1-17 years, median 4 years). Uncertainties are high but, importantly, quantifiable. This work provides for the first time a quantitative and transferable method and rationale on which to base long-term planning decisions for lava dome-forming volcanoes, with wide potential use and transferability to forecasts of other types of eruptions and other adverse events across the geohazard spectrum.
Community Evaluation of the National Diabetes Education Program's Diabetes HealthSense Website.
Sadler, Michele DeBarthe; Saperstein, Sandra L; Carpenter, Carrie; Devchand, Roshni; Tuncer, Diane; O'Brian, Catherine; Nicols, Christina; Gallivan, Joanne
2017-10-01
Purpose The purpose of this study was to assess the impact of Diabetes HealthSense on knowledge, attitudes, and behavior changes that prevent, delay, or manage diabetes among people at risk (PAR) for diabetes and people with diabetes (PWD). Methods Using a 2-group pretest-posttest design, 15 community sites were randomly assigned to either an intervention or comparison group. Intervention participants attended a group education session with a diabetes educator, followed by 4 weeks of independent use of the Diabetes HealthSense website. The comparison group received no intervention. A total of 311 adults (n = 135 intervention, n = 176 comparison) completed both a pretest and posttest. Outcome measures examined changes in self-reported knowledge, self-efficacy, and behaviors that support diabetes prevention or management. Results Statistically significant within-group pretest to posttest changes were found for almost all outcome measures in the intervention group, with no significant changes in the comparison group. Significant between-group differences were also found for almost all outcome measures at posttest, with the intervention group having more positive outcomes than the comparison group. Conclusions Patient referral to online tools is considered one key component of initial and ongoing diabetes self-management education and support (DSME/S) and is recommended as a way to enhance and extend the reach of in-person diabetes education. Positive outcomes were found for PWD/PAR who used Diabetes HealthSense following a guided education session. Study results suggested that with guided exploration, Diabetes HealthSense provided a valuable tool for educators to use with patients to support and extend the reach of DSME/S.
Caravanos, Jack; Ericson, Bret; Ponce-Canchihuamán, Johny; Hanrahan, David; Block, Meredith; Susilorini, Budi; Fuller, Richard
2013-11-01
Previous studies have evaluated associated health risks and human exposure pathways at mining sites. Others have provided estimates of the scale of the issue based in part on surveys. However, a global census of mining-related hazardous waste sites has been lacking. The Toxic Sites Identification Program (TSIP) implemented by Blacksmith Institute (New York, NY, USA) since 2009 is an ongoing effort to catalogue a wide range of chemically contaminated sites with a potential human health risk (Ericson et al., Environ Monit Assess doi:10.1007/s 10661-012-2665-2, 2012). The TSIP utilizes a rapid assessment instrument, the Initial Site Screening (ISS), to quickly and affordably identify key site criteria including human exposure pathways, estimated populations at risk, and sampling information. The resulting ISS allows for comparison between sites exhibiting different contaminants and pollution sources. This paper explores the results of a subset of ISSs completed at 131 artisanal and small-scale gold mining areas and 275 industrial mining and ore processing sites in 45 countries. The authors show that the ISS captures key data points, allowing for prioritization of sites for further investigation or remedial activity.
Statistical and Spatial Analysis of Bathymetric Data for the St. Clair River, 1971-2007
Bennion, David
2009-01-01
To address questions concerning ongoing geomorphic processes in the St. Clair River, selected bathymetric datasets spanning 36 years were analyzed. Comparisons of recent high-resolution datasets covering the upper river indicate a highly variable, active environment. Although statistical and spatial comparisons of the datasets show that some changes to the channel size and shape have taken place during the study period, uncertainty associated with various survey methods and interpolation processes limit the statistically certain results. The methods used to spatially compare the datasets are sensitive to small variations in position and depth that are within the range of uncertainty associated with the datasets. Characteristics of the data, such as the density of measured points and the range of values surveyed, can also influence the results of spatial comparison. With due consideration of these limitations, apparently active and ongoing areas of elevation change in the river are mapped and discussed.
Discriminated Timeout Avoidance in Pigeons: The Roles of Added Stimuli
ERIC Educational Resources Information Center
DeFulio, Anthony; Hackenberg, Timothy D.
2007-01-01
Two experiments examined pigeons' postponement of a signaled extinction period, or timeout (TO), from an ongoing schedule of response-dependent food delivery. A concurrent-operant procedure was used in which responses on one (food) key produced food according to a variable-interval schedule and responses on a second (postponement) key delayed the…
Flood risk perception and adaptation capacity: a contribution to the socio-hydrology debate
NASA Astrophysics Data System (ADS)
Fuchs, Sven; Karagiorgos, Konstantinos; Kitikidou, Kyriaki; Maris, Fotios; Paparrizos, Spyridon; Thaler, Thomas
2017-04-01
Dealing with flood hazard and risk requires approaches rooted both in natural and social sciences, which provided the nexus for the ongoing debate on socio-hydrology. Various combinations of non-structural and structural flood risk reduction options are available to communities. Focusing on flood risk and the information associated with it, developing risk management plans is required but often overlooking public perception of a threat. The perception of risk varies in many different ways, especially between the authorities and the affected public. It is because of this disconnection that many risk management plans concerning floods have failed in the past. This paper examines the private adaptation capacity and willingness with respect to flooding in two different catchments in Greece prone to multiple flood events during the last 20 years. Two studies (East Attica and Evros) were carried out, comprised of a survey questionnaire of 155 and 157 individuals, from a peri-urban (East Attica) and a rural (Evros) area, respectively, and they focused on those vulnerable to periodical (rural area) and flash floods (peri-urban area). Based on the comparisons drawn from these responses, and identifying key issues to be addressed when flood risk management plans are implemented, improvements are being recommended for the social dimension surrounding such implementation. As such, the paper contributes to the ongoing discussion on human-environment interaction in socio-hydrology.
Flood risk perception and adaptation capacity: a contribution to the socio-hydrology debate
NASA Astrophysics Data System (ADS)
Fuchs, Sven; Karagiorgos, Konstantinos; Kitikidou, Kyriaki; Maris, Fotios; Paparrizos, Spyridon; Thaler, Thomas
2017-06-01
Dealing with flood hazard and risk requires approaches rooted in both natural and social sciences, which provided the nexus for the ongoing debate on socio-hydrology. Various combinations of non-structural and structural flood risk reduction options are available to communities. Focusing on flood risk and the information associated with it, developing risk management plans is required but often overlooks public perception of a threat. The perception of risk varies in many different ways, especially between the authorities and the affected public. It is because of this disconnection that many risk management plans concerning floods have failed in the past. This paper examines the private adaptation capacity and willingness with respect to flooding in two different catchments in Greece prone to multiple flood events during the last 20 years. Two studies (East Attica and Evros) were carried out, comprised of a survey questionnaire of 155 and 157 individuals, from a peri-urban (East Attica) and a rural (Evros) area, respectively, and they focused on those vulnerable to periodic (rural area) and flash floods (peri-urban area). Based on the comparisons drawn from these responses, and identifying key issues to be addressed when flood risk management plans are implemented, improvements are being recommended for the social dimension surrounding such implementation. As such, the paper contributes to the ongoing discussion on human-environment interaction in socio-hydrology.
ERIC Educational Resources Information Center
Smidt, Jon
2011-01-01
What are the "key competencies" needed in our time? What literacy is needed to make students active participants in their societies and contributors to changing cultures? This article offers a contribution to the ongoing discussion about these questions. It takes as its point of departure the "key competencies" formulated in…
Holtyn, August F; Kaminski, Barbara J; Weerts, Elise M
2017-10-01
Baclofen, a GABA B receptor agonist, is under investigation as a pharmacotherapy for alcohol use disorder. Treatment with a pharmacotherapeutic can be initiated during alcohol abstinence or active drinking, which may influence treatment outcomes. This study examined whether baclofen treatment initiated and maintained during alcohol abstinence would reduce alcohol seeking and self-administration upon return to alcohol access, and whether effects differed from treatment initiated and maintained during ongoing alcohol access. Naltrexone was tested under similar conditions for comparison. Five baboons self-administered alcohol under a three-component chained schedule of reinforcement that modeled periods of anticipation (Component 1), seeking (Component 2), and consumption (Component 3). Alcohol was only available in Component 3. In Experiment 1, baclofen (0.1-1.8mg/kg) or naltrexone (1.0-5.6mg/kg) was administered daily beginning on the first day of a 5-day abstinence period and treatment was continued for 5days of alcohol access. In Experiment 2, selected doses of both drugs were administered during ongoing alcohol access. When treatment was initiated during alcohol abstinence, baclofen and naltrexone did not significantly reduce total alcohol intake (g/kg) or alcohol seeking. In comparison, when treatment was initiated during ongoing alcohol access, both baclofen (1.8mg/kg) and naltrexone (3.2 and 5.6mg/kg) significantly reduced total alcohol intake (g/kg). Naltrexone (5.6mg/kg), but not baclofen, significantly reduced alcohol seeking. Initiation of baclofen treatment (or other alcohol use disorder treatments) during abstinence or active drinking may be an important factor in influencing efficacy and appropriate dose selection. Copyright © 2017 Elsevier B.V. All rights reserved.
International comparison CCQM-K111.1—propane in nitrogen
NASA Astrophysics Data System (ADS)
van der Veen, Adriaan M. H.; Wouter van der Hout, J.; Ziel, Paul R.; Jozela, Mudalo; Tshilongo, James; Ntsasa, Napo G.; Botha, Angelique
2017-01-01
This key comparison aims to assess the core capabilities of the participants in gas analysis. Such competences include, among others, the capability of preparing Primary Standard gas Mixtures (PSMs), performing the necessary purity analysis on the materials used in the gas mixture preparation, the verification of the composition of newly prepared PSMs against existing ones, and the capability of calibrating the composition of a gas mixture. According to the Strategy for Key Comparisons of the Gas Analysis Working Group, this subsequent key comparison is classified as a track B key comparison, which means that the results of this key comparison can be used to underpin calibration and measurement capabilities for propane under the default scheme. The artefact was a binary mixture of propane in nitrogen at a nominal amount-of-substance fraction level of 1000 μmol/mol. The values and uncertainties from the gravimetric gas mixture preparation were used as key comparison reference values (KCRVs). Each transfer standard had its own KCRV. The result of the participating laboratory is consistent with the key comparison reference value within the respective expanded uncertainties and deviates less than 0.1 %. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Immune Checkpoint Inhibition in Hepatocellular Carcinoma: Basics and Ongoing Clinical Trials.
Kudo, Masatoshi
2017-01-01
Clinical trials of antibodies targeting the immune checkpoint inhibitors programmed cell death 1 (PD-1), programmed cell death ligand 1 (PD-L1), or cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) for the treatment of advanced hepatocellular carcinoma (HCC) are ongoing. Expansion cohorts of a phase I/II trial of the anti-PD-1 antibody nivolumab in advanced HCC showed favorable results. Two phase III studies are currently ongoing: a comparison of nivolumab and sorafenib in the first-line setting for advanced HCC, and a comparison of the anti-PD-1 antibody pembrolizumab and a placebo in the second-line setting for patients with advanced HCC who progressed on sorafenib therapy. The combination of anti-PD-1/PD-L1 and anti-CTLA-4 antibodies is being evaluated in other phase I/II trials, and the results suggest that an anti-PD-1 antibody combined with locoregional therapy or other molecular targeted agents is an effective treatment strategy for HCC. Immune checkpoint inhibitors may therefore open new doors to the treatment of HCC. © 2017 S. Karger AG, Basel.
Final report on COOMET Vickers PTB/VNIIFTRI key comparison (COOMET.M.H-K1.b and COOMET.M.H-K1.c)
NASA Astrophysics Data System (ADS)
Aslanyan, E.; Herrmann, K.
2013-01-01
This report describes a COOMET key comparison on Vickers hardness scales of two National Metrology Institutes—PTB and VNIIFTRI. The pilot laboratory was PTB, which was the linking institute with the key comparison reference values of CCM.H-K1. In the key comparison two sets of hardness reference blocks for the Vickers hardness scales HV1 and HV30, each consisting of three hardness reference blocks with the hardness levels 240 HV, 540 HV and 840 HV, are used. The same hardness reference blocks were used previously in the key comparison CCM.H-K1. The measurement results and uncertainty assessments, announced by VNIIFTRI, are in good agreement with the key comparison reference values of CCM.H-K1. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Hotel shows health system keys to service excellence.
2003-08-01
Ritz-Carlton partnership part of broader program pursuing service excellence. Nearly 600 system leaders will participate in day-long seminars. GE, Harvard serve as strategic partners for ongoing educational efforts.
NASA Technical Reports Server (NTRS)
1974-01-01
Key lessons learned during the Skylab Program that could have impact on on-going and future programs are presented. They present early and sometimes subjective opinions; however, they give insights into key areas of concern. These experiences from a complex space program management and space flight serve as an early assessment to provide the most advantage to programs underway. References to other more detailed reports are provided.
Mahat-Shamir, Michal; Hamama-Raz, Yaira; Ben-Ezra, Menachem; Pitcho-Prelorentzos, Shani; Zaken, Adi; David, Udi Y; Bergman, Yoav S
2018-03-01
The current study examined whether emotional concern over one's security situation is connected with death anxiety during an ongoing terror wave, and whether type of exposure (media exposure vs. contact with witnesses) moderates this connection. A total of 345 individuals, aged 18-70, were sampled during an ongoing wave of terror in Israel and filled out scales measuring death anxiety, concern over security situation, and type of exposure. Results indicated that increased concern was connected with enhanced death anxiety. Moreover, this connection was more pronounced among individuals exposed to the events through the media, in comparison with individuals who had first-hand contact with witnesses.
KEY COMPARISON: Final report on CCQM-K69 key comparison: Testosterone glucuronide in human urine
NASA Astrophysics Data System (ADS)
Liu, Fong-Ha; Mackay, Lindsey; Murby, John
2010-01-01
The CCQM-K69 key comparison of testosterone glucuronide in human urine was organized under the auspices of the CCQM Organic Analysis Working Group (OAWG). The National Measurement Institute Australia (NMIA) acted as the coordinating laboratory for the comparison. The samples distributed for the key comparison were prepared at NMIA with funding from the World Anti-Doping Agency (WADA). WADA granted the approval for this material to be used for the intercomparison provided the distribution and handling of the material were strictly controlled. Three national metrology institutes (NMIs)/designated institutes (DIs) developed reference methods and submitted data for the key comparison along with two other laboratories who participated in the parallel pilot study. A good selection of analytical methods and sample workup procedures was displayed in the results submitted considering the complexities of the matrix involved. The comparability of measurement results was successfully demonstrated by the participating NMIs. Only the key comparison data were used to estimate the key comparison reference value (KCRV), using the arithmetic mean approach. The reported expanded uncertainties for results ranged from 3.7% to 6.7% at the 95% level of confidence and all results agreed within the expanded uncertainty of the KCRV. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
Fatigue and Fracture Branch: A compendium of recently completed and on-going research projects
NASA Technical Reports Server (NTRS)
Elber, W.
1984-01-01
This compendium of recently completed and ongoing research projects from the Fatigue and Fracture Branch at NASA Langley Research Center provides technical descriptions and key results of all such projects expected to lead to publication of significant findings. The common thread to all these studies is the application of fracture mechanics analyses to engineering problems in metals and composites, with particular emphasis on airframe structural materials. References to recent publications are included where appropriate.
Stone, Mark H; Stenner, A Jackson
2014-01-01
Several concepts from Georg Rasch's last papers are discussed. The key one is comparison because Rasch considered the method of comparison fundamental to science. From the role of comparison stems scientific inference made operational by a properly developed frame of reference producing specific objectivity. The exact specifications Rasch outlined for making comparisons are explicated from quotes, and the role of causality derived from making comparisons is also examined. Understanding causality has implications for what can and cannot be produced via Rasch measurement. His simple examples were instructive, but the implications are far reaching upon first establishing the key role of comparison.
Livingood, William C; Peden, Angela H; Shah, Gulzar H; Marshall, Nandi A; Gonzalez, Ketty M; Toal, Russell B; Alexander, Dayna S; Wright, Alesha R; Woodhouse, Lynn D
2015-07-31
Public health agencies in the USA are increasingly challenged to adopt Quality Improvement (QI) strategies to enhance performance. Many of the functional and structural barriers to effective use of QI can be found in the organizational culture of public health agencies. The purpose of this study was to assess the impact of public health practice based research network (PBRN) evaluation and technical assistance for QI interventions on the organizational culture of public health agencies in Georgia, USA. An online survey of key informants in Georgia's districts and county health departments was used to compare perceptions of characteristics of organizational QI culture between PBRN supported QI districts and non-PBRN supported districts before and after the QI interventions. The primary outcomes of concern were number and percentage of reported increases in characteristics of QI culture as measured by key informant responses to items assessing organizational QI practices from a validated instrument on QI Collaboratives. Survey results were analyzed using Multi-level Mixed Effects Logistic Model, which accounts for clustering/nesting. Increases in QI organizational culture were consistent for all 10- items on a QI organizational culture survey related to: leadership support, use of data, on-going QI, and team collaboration. Statistically significant odds ratios were calculated for differences in increased QI organizational culture between PBRN-QI supported districts compared to Non-PBRN supported districts for 5 of the 10 items, after adjusting for District clustering of county health departments. Agency culture, considered by many QI experts as the main goal of QI, is different than use of specific QI methods, such as Plan-Do-Study-Act (PDSA) cycles or root-cause analyses. The specific use of a QI method does not necessarily reflect culture change. Attempts to measure QI culture are newly emerging. This study documented significant improvements in characteristics of organizational culture and demonstrated the potential of PBRNs to support agency QI activities.
Final report of the APMP water flow key comparison: APMP.M.FF-K1
NASA Astrophysics Data System (ADS)
Lee, Kwang-Bock; Chun, Sejong; Terao, Yoshiya; Thai, Nguyen Hong; Tsair Yang, Cheng; Tao, Meng; Gutkin, Mikhail B.
2011-01-01
The key comparison, APMP.M.FF-K1, was undertaken by APMP/TCFF, the Technical Committee for Fluid Flow (TCFF) under the Asia Pacific Metrology Program (APMP). One objective of the key comparison was to demonstrate the degree of equivalence among six participating laboratories (KRISS, NMIJ, VMI, CMS, NIM and VNIIM) in water flow rate metrology by comparing the results with the key comparison reference value (KCRV) determined from the CCM.FF-K1 key comparison. The other objective of this key comparison was to provide supporting evidence for the calibration and measurement capabilities (CMCs), which had been declared by the participating laboratories during this key comparison. The Transfer Standard Package (TSP) was a Coriolis mass flowmeter, which had been used in the CCM.FF-K1 key comparison. Because the K-factors in the APMP.M.FF-K1 key comparison were slightly lower than the K-factors of the CCM.FF-K1 key comparison due to long-term drifts of the TSP, a correction value D was introduced. The value of D was given by a weighted sum between two link laboratories (NMIJ and KRISS), which participated in both the CCM.FF-K1 and the APMP.M.FF-K1 key comparisons. By this correction, the K-factors were laid between 12.004 and 12.017 at either low (Re = 254 000) or high (Re = 561 000) flow rates. Most of the calibration data were within expected uncertainty bounds. However, some data showed undulations, which gave large fluctuations of the metering factor at Re = 561 000. Calculation of degrees of equivalence showed that all the participating laboratories had deviations between -0.009 and 0.007 pulses/kg from the CCM.FF-K1 KCRV at either the low or the high flow rates. In case of En calculation, all the participating laboratories showed values less than 1, indicating that the corrected K-factors of all the laboratories were equivalent with the KCRV at both Re = 254 000 and 561 000. When the corrected K-factors from two participating laboratories were compared, all the numbers of equivalence showed values less than 1, indicating equivalence. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Hung, Chen-Chuan; Jian, Wu; Changpan, Tawat
2009-01-01
This report describes the key comparison APMP.M.P-K6.1 among the three national metrology institutes, Center for Measurement Standards-ITRI (CMS-ITRI, Taiwan), SPRING Singapore and National Institute of Metrology (NIMT), in the pressure range from 20 kPa to 105 kPa in gas media and gauge mode executed during the period April 2003 to April 2004. This comparison was conducted by CMS-ITRI and was based on the calibration procedure of APMP pneumatic pressure comparison APMP.M.P-K6. We intended to link to the CCM.P-K6 key comparison through the APMP.M.P-K6 key comparison by using the proposed linkage method in the APMP.M.P-K6 key comparison to determine a linking factor that can transform the quantities measured in the APMP.M.P-K6.1 key comparison. All three participating institutes used pneumatic piston gauges as their pressure standards. The Ruska 2465 gas-operated piston-cylinder assembly TL-1409 used as transfer standard offered by CMS-ITRI was calibrated three times by the pilot institute during the comparison period and showed that it was very stable after evaluation. The comparison was conducted on the basis of cross-float experiments to determine the effective area of transfer standards from the national standards of three institutes. The comparison results (as shown in Table 6) were equivalent to the CCM.P-K6 comparison and the relative bilateral degrees of equivalence between two laboratories were smaller than 39.7 × 10-6 from 20 kPa to 105 kPa. These results showed all participating institutes measuring the same quantity in the whole pressure range lay within their expanded uncertainty with confidence level 95%. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
APMP.QM-K111—propane in nitrogen
NASA Astrophysics Data System (ADS)
Lin, Tsai-Yin; Liu, Hsin-Wang; Huang, Chiung-Kun; Kang, Namgoo; Bae, Hyun Kil; Woo, Jin Chun; Bi, Zhe; Zhou, Zeyi; Sinweeruthai, Ratirat; Wongjuk, Arnuttachai; Li, Hou; Beng Keat, Teo; Hui, Liu; Wu, Thomas; Hock Ann, Chua; Smeulders, Damian; Briton McCallum, John; Tendai Satumba, Raymond; Shimosaka, Takuya; Matsumoto, Nobuhiro; Kadir, Haslina Abdul; Fauzi Ahmad, Mohamad; Nasir, Noor Hidaya Abdul; Nishino, Tomoe; Akima, Dai; Uehara, Shinji
2018-01-01
This document describes the result of a key comparison for propane in nitrogen. The nominal amount-of-substance fraction of propane is 1000 μmol/mol. The comparison aimed to assess the measurement capability of participants in gas analysis. Nine NMIs or DIs participated in the comparison. CERI participated in a key comparison CCQM-K111—propane in nitrogen, and coordinated this key comparison. Therefore, every participants' results of this comparison are linking to the CCQM-K111. Gravimetric values of the samples were used as key comparison reference values (KCRVs). Measured values of eight participants were within +/- 0.25 % of the KCRVs. Many participants reported purity or impurity analysis of materials. These results are also able to assess the participants' capability of the analysis. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Francis, Olivier; Klein, Gilbert; Baumann, Henri; Dando, Nicolas; Tracey, Ray; Ullrich, Christian; Castelein, Stefaan; Hua, Hu; Kang, Wu; Chongyang, Shen; Songbo, Xuan; Hongbo, Tan; Zhengyuan, Li; Pálinkás, Vojtech; Kostelecký, Jakub; Mäkinen, Jaakko; Näränen, Jyri; Merlet, Sébastien; Farah, Tristan; Guerlin, Christine; Pereira Dos Santos, Franck; Le Moigne, Nicolas; Champollion, Cédric; Deville, Sabrina; Timmen, Ludger; Falk, Reinhard; Wilmes, Herbert; Iacovone, Domenico; Baccaro, Francesco; Germak, Alessandro; Biolcati, Emanuele; Krynski, Jan; Sekowski, Marcin; Olszak, Tomasz; Pachuta, Andrzej; Agren, Jonas; Engfeldt, Andreas; Reudink, René; Inacio, Pedro; McLaughlin, Daniel; Shannon, Geoff; Eckl, Marc; Wilkins, Tim; van Westrum, Derek; Billson, Ryan
2012-01-01
During November 2011 a EURAMET key comparison of absolute gravimeters was organized in the Underground Laboratory for Geodynamics in Walferdange, Luxemburg. The comparison assembled 22 participants coming from 16 countries and four different continents. The comparison was divided into two parts: a key comparison that included six National Metrology Institutes or Designated Institutes, and a pilot study including all participants. The global result given by the pilot study confirms that all instruments are absolutely coherent with each other. The results obtained in the key comparison confirm a good agreement between the NMI instruments. Finally, a link to ICAG-2009 shows also that the NMI gravimeters are stable in time. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Powell, Justin J W; Dusdal, Jennifer
2017-01-01
Charting significant growth in science production over the 20th century in four European Union member states, this neo-institutional analysis describes the development and current state of universities and research institutes that bolster Europe's position as a key region in global science. On-going internationalization and Europeanization of higher education and science has been accompanied by increasing competition as well as collaboration. Despite the policy goals to foster innovation and further expand research capacity, in cross-national and historical comparison neither the level of R&D investments nor country size accounts completely for the differential growth of scientific productivity. Based on a comprehensive historical database from 1900 to 2010, this analysis uncovers both stable and dynamic patterns of production and productivity in Germany, France, Belgium, and Luxembourg. Measured in peer-reviewed research articles collected in Thomson Reuters' Science Citation Index Expanded, which includes journals in the fields of Science, Technology, Engineering, Mathematics, and Health, we show the varying contributions of different organizational forms, especially research universities and research institutes. Comparing the institutionalization pathways that created the conditions necessary for continuous and strong growth in scientific productivity in the European center of global science emphasizes that the research university is the key organizational form across countries.
Geodetic mass balance of key glaciers across High Mountain Asia: a multi-decadal survey
NASA Astrophysics Data System (ADS)
Maurer, J. M.; Schaefer, J. M.; Rupper, S.; Corley, A. D.
2016-12-01
Glaciers in High Mountain Asia (HMA) supply seasonal meltwater for large populations, yet field observations are scarce and glacier sensitivities are poorly understood. In order to link complex atmospheric driving factors with heterogeneous glacier responses, detailed remote sensing observations of past changes in ice volume are needed. Here we compile a spatially and temporally extensive satellite-based remote sensing record to quantify multi-decadal geodetic mass balance of large mountain glaciers across key regions in HMA, including the Pamir, Himachal Pradesh, Uttarakhand, Nepal, Sikkim, and Bhutan regions. By utilizing declassified spy satellite imagery from the 1970's, ASTER scenes spanning 2000-present, and the ALOS global digital surface model, a methodologically homogenous assessment of regional and individual glacier responses to climate change over several decades is obtained. Although gaps due to low radiometric contrast result in significant uncertainties, the consistent approach across the HMA provides a useful comparison of relative geodetic changes between climatically diverse regions. Various patterns of ice loss are observed, including dynamic retreat of clean-ice glaciers and downwasting of debris-covered glaciers. In particular, we highlight the pronounced thinning and retreat of glaciers undergoing calving into proglacial lakes, which has important implications regarding ongoing and future ice loss of HMA glaciers.
NASA Astrophysics Data System (ADS)
Impey, C.; Buxner, S.; Antonellis, J.; CATS
2013-04-01
This talk presents findings related to our ongoing work investigating students' knowledge and attitudes towards science and technology. We present an overview of research studies and findings including a comparison of the science literacy measures of University of Arizona students compared to national studies, conceptions related to astrology, views of radiation, and students' pseudoscience and religious beliefs. We discuss implications for instructors and researchers interested in improving students' science literacy scores and diagnosing alternative beliefs.
Annemans, Lieven
2008-01-01
The optimal adjuvant hormonal strategy in post-menopausal women with early breast cancer is a subject of ongoing debate. Aromatase inhibitors (AIs) have been successfully evaluated in clinical trials that have compared them with a standard treatment of 5 years of tamoxifen. However, several options are available in terms of treatment schedule and selected drug. Systematic reviews of clinical trials and health economic evaluations attempt to contribute to the debate. The objective of this paper is to provide a critical review of existing health economic evaluations with a focus on those parameters and assumptions with the largest impact on final outcomes.A wide range of different inputs and assumptions exist, which make a comparison of results difficult, if not impossible. In particular, the modelling of recurrence rates over longer time horizons than those observed in clinical trials, a cornerstone of health economic modelling, is subject to quite different approaches. The practice of indirect comparison of different AIs without sufficiently acknowledging population differences is also bothersome. A list of key features (related to time horizon, clinical data input, patient subtypes, budget impact and model calibration) that an ideal model should have in order to better assist decision makers in this field is proposed.
Evaluation of simulated ocean carbon in the CMIP5 earth system models
NASA Astrophysics Data System (ADS)
Orr, James; Brockmann, Patrick; Seferian, Roland; Servonnat, Jérôme; Bopp, Laurent
2013-04-01
We maintain a centralized model output archive containing output from the previous generation of Earth System Models (ESMs), 7 models used in the IPCC AR4 assessment. Output is in a common format located on a centralized server and is publicly available through a web interface. Through the same interface, LSCE/IPSL has also made available output from the Coupled Model Intercomparison Project (CMIP5), the foundation for the ongoing IPCC AR5 assessment. The latter includes ocean biogeochemical fields from more than 13 ESMs. Modeling partners across 3 EU projects refer to the combined AR4-AR5 archive and comparison as OCMIP5, building on previous phases of OCMIP (Ocean Carbon Cycle Intercomparison Project) and making a clear link to IPCC AR5 (CMIP5). While now focusing on assessing the latest generation of results (AR5, CMIP5), this effort is also able to put them in context (AR4). For model comparison and evaluation, we have also stored computed derived variables (e.g., those needed to assess ocean acidification) and key fields regridded to a common 1°x1° grid, thus complementing the standard CMIP5 archive. The combined AR4-AR5 output (OCMIP5) has been used to compute standard quantitative metrics, both global and regional, and those have been synthesized with summary diagrams. In addition, for key biogeochemical fields we have deconvolved spatiotemporal components of the mean square error in order to constrain which models go wrong where. Here we will detail results from these evaluations which have exploited gridded climatological data. The archive, interface, and centralized evaluation provide a solid technical foundation, upon which collaboration and communication is being broadened in the ocean biogeochemical modeling community. Ultimately we aim to encourage wider use of the OCMIP5 archive.
Robinson, C A; Smith, K L; Norris, S
2010-06-01
This paper provides an overview of key issues associated with the application of currently available biota dose assessment methods to consideration of potential environmental impacts from geological disposal facilities. It explores philosophical, methodological and practical assessment issues and reviews the implications of test assessment results in the context of recent and on-going challenges and debates.
Sports Injury Surveillance Systems: A Review of Methods and Data Quality.
Ekegren, Christina L; Gabbe, Belinda J; Finch, Caroline F
2016-01-01
Data from sports injury surveillance systems are a prerequisite to the development and evaluation of injury prevention strategies. This review aimed to identify ongoing sports injury surveillance systems and determine whether there are gaps in our understanding of injuries in certain sport settings. A secondary aim was to determine which of the included surveillance systems have evaluated the quality of their data, a key factor in determining their usefulness. A systematic search was carried out to identify (1) publications presenting methodological details of sports injury surveillance systems within clubs and organisations; and (2) publications describing quality evaluations and the quality of data from these systems. Data extracted included methodological details of the surveillance systems, methods used to evaluate data quality, and results of these evaluations. Following literature search and review, a total of 15 sports injury surveillance systems were identified. Data relevant to each aim were summarised descriptively. Most systems were found to exist within professional and elite sports. Publications concerning data quality were identified for seven (47%) systems. Validation of system data through comparison with alternate sources has been undertaken for only four systems (27%). This review identified a shortage of ongoing injury surveillance data from amateur and community sport settings and limited information about the quality of data in professional and elite settings. More surveillance systems are needed across a range of sport settings, as are standards for data quality reporting. These efforts will enable better monitoring of sports injury trends and the development of sports safety strategies.
Methodology or method? A critical review of qualitative case study reports.
Hyett, Nerida; Kenny, Amanda; Dickson-Swift, Virginia
2014-01-01
Despite on-going debate about credibility, and reported limitations in comparison to other approaches, case study is an increasingly popular approach among qualitative researchers. We critically analysed the methodological descriptions of published case studies. Three high-impact qualitative methods journals were searched to locate case studies published in the past 5 years; 34 were selected for analysis. Articles were categorized as health and health services (n=12), social sciences and anthropology (n=7), or methods (n=15) case studies. The articles were reviewed using an adapted version of established criteria to determine whether adequate methodological justification was present, and if study aims, methods, and reported findings were consistent with a qualitative case study approach. Findings were grouped into five themes outlining key methodological issues: case study methodology or method, case of something particular and case selection, contextually bound case study, researcher and case interactions and triangulation, and study design inconsistent with methodology reported. Improved reporting of case studies by qualitative researchers will advance the methodology for the benefit of researchers and practitioners.
A comparison of WEC control strategies
DOE Office of Scientific and Technical Information (OSTI.GOV)
Wilson, David G.; Bacelli, Giorgio; Coe, Ryan Geoffrey
2016-04-01
The operation of Wave Energy Converter (WEC) devices can pose many challenging problems to the Water Power Community. A key research question is how to significantly improve the performance of these WEC devices through improving the control system design. This report summarizes an effort to analyze and improve the performance of WEC through the design and implementation of control systems. Controllers were selected to span the WEC control design space with the aim of building a more comprehensive understanding of different controller capabilities and requirements. To design and evaluate these control strategies, a model scale test-bed WEC was designed formore » both numerical and experimental testing (see Section 1.1). Seven control strategies have been developed and applied on a numerical model of the selected WEC. This model is capable of performing at a range of levels, spanning from a fully-linear realization to varying levels of nonlinearity. The details of this model and its ongoing development are described in Section 1.2.« less
Outage differences between Diablo Canyon and Unterweser power plants
DOE Office of Scientific and Technical Information (OSTI.GOV)
Mehrens, H.
Diablo Canyon (DCPP) of Pacific Gas and Electric Company and Unterweser (KKU) of PreussenElektra have had an ongoing exchange program since 1989, which includes mutual visits by their employees at the optimum time for observing outages. Both DCPP and Unterweser use four-loop pressurized water reactors (PWRs), DCPP with two 1,100-MW units and KKU with a single 1,300-MW unit. Unterweser finished its 11th outage in 1990; DCPP units 1 and 2 will have their fourth outages in 1991. The scope of the maintenance and refueling work is quite similar in both plants and offers, therefore, a good basis for comparison. Outagemore » durations at European Kraftwerk Union KWU-PWR plants average {approximately}30 days as compared to the 60 to 80 days for PWRs in the US. Diablo Canyon has reduced outage durations from > 100 days to < 60. The key areas that contribute to the differences in outage duration are plant design and layout and outage execution.« less
International comparison CCQM-K111—propane in nitrogen
NASA Astrophysics Data System (ADS)
van der Veen, Adriaan M. H.; Wouter van der Hout, J.; Ziel, Paul R.; Oudwater, Rutger J.; Fioravante, Andreia L.; Augusto, Cristiane R.; Coutinho Brum, Mariana; Uehara, Shinji; Akima, Dai; Bae, Hyun Kil; Kang, Namgoo; Woo, Jin-Chun; Liaskos, Christina E.; Rhoderick, George C.; Jozela, Mudalo; Tshilongo, James; Ntsasa, Napo G.; Botha, Angelique; Brewer, Paul J.; Brown, Andrew S.; Bartlett, Sam; Downey, Michael L.; Konopelko, L. A.; Kolobova, A. V.; Pankov, A. A.; Orshanskaya, A. A.; Efremova, O. V.
2017-01-01
This key comparison aims to assess the core capabilities of the participants in gas analysis. Such competences include, among others, the capabilities to prepare primary standard gas Mixtures (PSMs), perform the necessary purity analysis on the materials used in the gas mixture preparation, the verification of the composition of newly prepared PSMs against existing ones, and the capability of calibrating the composition of a gas mixture. According to the Strategy for Key Comparisons of the Gas Analysis Working Group, this key comparison is classified as a track A key comparison, which means that the results of this key comparison can be used to underpin calibration and measurement capabilities using the flexible scheme, and for propane under the default scheme. The artefacts were binary mixtures of propane in nitrogen at a nominal amount-of-substance fraction level of 1000 μmol/mol. The values and uncertainties from the gravimetric gas mixture preparation were used as key comparison reference values (KCRVs). Each transfer standard had its own KCRV. The results are generally good. All results but one are within +/- 0.2 % of the KCRV. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Clinical Investigation Program Annual Progress Report
1993-09-30
272 93/200A 0 Comparison of Healing Rates of Bones Plated Following Fracture, Among Yucatan Swine Having Open and Closed Physes...Study Objective: Compare two enteral formulas in respect to nutritional aspects. (16) Technical Approach: Protocol will take place in SICU. (17...Protocol #: 93/200A (3) Status: Ongoing (4) Title: Comparison of Healing Rates of Bones Plated Following Fractures, Among Yucatan Swine Having Open and
NASA Astrophysics Data System (ADS)
Becerra, Luis Omar
2009-01-01
This SIM comparison on the calibration of high accuracy hydrometers was carried out within fourteen laboratories in the density range from 600 kg/m3 to 1300 kg/m3 in order to evaluate the degree of equivalence among participant laboratories. This key comparison anticipates the planned key comparison CCM.D-K4, and is intended to be linked with CCM.D-K4 when results are available. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
International comparison Euramet.QM-K111—propane in nitrogen
NASA Astrophysics Data System (ADS)
Wouter van der Hout, J.; van der Veen, Adriaan M. H.; Ziel, Paul R.; Kipphardt, Heinrich; Tuma, Dirk; Maiwald, Michael; Fernández, Teresa E.; Gómez, Concepción; Cieciora, Dariusz; Ochman, Grzegorz; Dias, Florbela; Silvino, Victor; Macé, Tatiana; Sutour, Christophe; Marioni, Fabrice; Ackermann, Andreas; Niederhauser, Bernhard; Fükő, Judit; Büki, Tamás; Nagyné Szilágyi, Zsófia; Tarhan, Tanıl; Engin, Erinç
2017-01-01
This key comparison aims to assess the core capabilities of the participants in gas analysis. Such competences include, among others, the capabilities to prepare Primary Standard gas Mixtures (PSMs), perform the necessary purity analysis on the materials used in the gas mixture preparation, the verification of the composition of newly prepared PSMs against existing ones, and the capability of calibrating the composition of a gas mixture. According to the Strategy for Key Comparisons of the Gas Analysis Working Group, this key comparison is classified as an RMO track A key comparison. The artefacts were binary mixtures of propane in nitrogen at a nominal amount-of-substance fraction level of 1000 μmol/mol. The values and uncertainties from the gravimetric gas mixture preparation were used as key comparison reference values (KCRVs). Each transfer standard had its own KCRV. The results are generally good. All results are within +/- 1 % of the KCRV. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Final report on RMO Vickers key comparison COOMET M.H-K1
NASA Astrophysics Data System (ADS)
Aslanyan, E.; Menelao, F.; Herrmann, K.; Aslanyan, A.; Pivovarov, V.; Galat, E.; Dovzhenko, Y.; Zhamanbalin, M.
2013-01-01
This report describes a COOMET key comparison on Vickers hardness scales involving five National Metrology Institutes: PTB (Germany), BelGIM (Belarus), NSC IM (Ukraine), KazInMetr (Kazakhstan) and VNIIFTRI (Russia). The pilot laboratory was VNIIFTRI, and PTB acted as the linking institute to key comparisons CCM.H-K1.b and CCM.H-K1.c conducted for the Vickers hardness scales HV1 and HV30, respectively. The comparison was also conducted for the HV5 Vickers hardness scale, since this scale is most frequently used in practice in Russia and CIS countries that work according to GOST standards. In the key comparison, two sets of hardness reference blocks for the Vickers hardness scales HV1, HV5 and HV30 consisting each of three hardness reference blocks with hardness levels of 450 HV and 750 HV were used. The measurement results and uncertainty assessments for HV1 and HV30 hardness scales, as announced by BelGIM, NSC IM, KazInMetr and VNIIFTRI, are in good agreement with the key comparison reference values of CCM.H-K1.b and CCM.H-K1.c. The comparison results for the HV5 hardness scale are viewed as additional information, since up to today no CCM key comparisons on this scale have yet been carried out. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Heinonen, Martti
2010-01-01
The first humidity CIPM key comparison, CCT-K6, will be completed in 2010. The corresponding European regional key comparison, EUROMET.T-K6, was carried out in 2004 to 2008. National metrology institutes from 24 countries participated in the comparison. The comparison covered the dew-point temperature range from -50 °C to +20 °C. It was organized as three parallel loops with two specially manufactured precision chilled mirror hygrometers as transfer standards in each loop. The comparison scheme was designed to ensure high quality results with evenly spread workload for the participants. MIKES was coordinating the project. This report presents the results of the comparison and provides detailed information on the measurements performed by all participating laboratories and the analysis of the results. Conclusions on the equivalence of the dew-point temperature standards are drawn on the basis of calculated bilateral degrees of equivalence and deviations from EURAMET comparison reference values (ERV). Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Burns, D. T.; Kessler, C.; Büermann, L.; Ketelhut, S.
2018-01-01
A key comparison has been made between the absorbed dose to water standards of the PTB, Germany and the BIPM in the medium-energy x-ray range. The results show the standards to be in general agreement at the level of the standard uncertainty of the comparison of 9 to 11 parts in 103. The results are combined with those of a EURAMET comparison and presented in terms of degrees of equivalence for entry in the BIPM key comparison database. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Reinforcer control by comparison-stimulus color and location in a delayed matching-to-sample task.
Alsop, Brent; Jones, B Max
2008-05-01
Six pigeons were trained in a delayed matching-to-sample task involving bright- and dim-yellow samples on a central key, a five-peck response requirement to either sample, a constant 1.5-s delay, and the presentation of comparison stimuli composed of red on the left key and green on the right key or vice versa. Green-key responses were occasionally reinforced following the dimmer-yellow sample, and red-key responses were occasionally reinforced following the brighter-yellow sample. Reinforcer delivery was controlled such that the distribution of reinforcers across both comparison-stimulus color and comparison-stimulus location could be varied systematically and independently across conditions. Matching accuracy was high throughout. The ratio of left to right side-key responses increased as the ratio of left to right reinforcers increased, the ratio of red to green responses increased as the ratio of red to green reinforcers increased, and there was no interaction between these variables. However, side-key biases were more sensitive to the distribution of reinforcers across key location than were comparison-color biases to the distribution of reinforcers across key color. An extension of Davison and Tustin's (1978) model of DMTS performance fit the data well, but the results were also consistent with an alternative theory of conditional discrimination performance (Jones, 2003) that calls for a conceptually distinct quantitative model.
Reducing Toxicity of Radiation Treatment of Advanced Prostate Cancer
2015-10-01
steady state hematopoiesis with normalization of the frequency of hematopoietic stem and progenitor cells. Moreover, hematopoietic stem cells from RTA...ongoing. 7 KEY RESEARCH ACCOMPLISHMENTS: • Identified radiation protection of different organ systems (GI tract, skin and hematopoiesis ) by RTA
Present and future of astronomy in Thailand
NASA Astrophysics Data System (ADS)
Soonthornthum, Boonrucksar
2018-05-01
Investments in national astronomical facilities and human resources through the National Astronomical Research Institute of Thailand have led to the rapid growth of astronomy in Thailand. Ongoing activities in key research areas, education and outreach will lead to further sustainable development.
KEY COMPARISON: CCQM-K21 Key Comparison Determination of pp’-DDT in fish oil
NASA Astrophysics Data System (ADS)
Webb, K. S.; Carter, D.; Wolff Briche, C. S. J.
2003-01-01
A key comparison on the determination of (pp'-dichlorodiphenyl) trichloroethane (pp'-DDT) in a fish oil matrix has been successfully completed. Nine NMIs participated in this key comparison and used the technique of isotope dilution gas-chromatography mass spectrometry (ID/GC/MS) for the determinations. Two samples (A and B) of fish oil were distributed to participants, each gravimetrically spiked with pp'-DDT. The KCRV for Sample A is 0.0743 +/- 0.0020 µg g-1 and that of Sample B is 0.1655 +/- 0.0014 µg g-1 of pp'-DDT in fish oil. The results for Sample A showed a RSD of 3.5%, the RSD for Sample B was within 1%. These results were an improvement over those of the corresponding pilot study (CCQM-P21), where at a mass fraction of pp'-DDT in fish oil of 0.311 µg g-1 the RSD was 2.6%. The compound pp'-DDT is a typical organochlorine pesticide and this key comparison has shown that NMIs have the ability to measure such compounds at levels typically found in the environment. The compound (pp'-dichlorodiphenyl) dichloroethylene (pp'-DDE), a metabolite of pp'-DDT, was the subject of a previous key comparison (CCQM-K5). The compound pp'-DDT is technically more challenging than that of pp'-DDE since it can decompose during the measurement procedure. Consequently the success of this key comparison, combined with that of CCQM-K5 demonstrates a broad measurement capability by NMIs for organochlorine compounds in the environment. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the Mutual Recognition Arrangement (MRA).
Acquisition of delayed matching in the pigeon.
Berryman, R; Cumming, W W; Nevin, J A
1963-01-01
Pigeons were exposed to three successive matching-to-sample procedures. On a given trial, the sample (red, green or blue light) appeared on a center key; observing responses to this key produced the comparison stimuli on two side keys. Seven different experimental conditions could govern the temporal relations between the sample and comparison stimuli. In the "simultaneous" condition, the center key response was followed immediately by illumination of the side key comparison stimuli, with the center key remaining on. In "zero delay" the center key response simultaneously turned the side keys on and the center key off, while in the "variable delay" conditions, intervals of 1, 2, 4, 10, and 24 sec were interposed between the offset of the sample and the appearance of the comparison stimuli on the side keys. In all conditions, a response to the side key of matching hue produced reinforcement, while a response to the non-matching side key was followed by a blackout. In procedure I all seven experimental conditions were presented in randomly permutated order. After nine sessions of exposure (at 191 trials per session, for a total of 1719 trials) the birds gave no evidence of acquisition in any of the conditions. They were therefore transferred to Procedure II, which required them to match only in the "simultaneous" condition, with both the sample and comparison stimuli present at the same time. With the exception of one bird, all subjects acquired this performance to near 100% levels. Next, in Procedure III, they were once more exposed to presentation of all seven experimental conditions in random order. In contrast to Procedure I, they now acquired the delay performance, and were able to match effectively at delays of about 4 sec.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Hill, P; Labby, Z; Bayliss, R A
Purpose: To develop a plan comparison tool that will ensure robustness and deliverability through analysis of baseline and online-adaptive radiotherapy plans using similarity metrics. Methods: The ViewRay MRIdian treatment planning system allows export of a plan file that contains plan and delivery information. A software tool was developed to read and compare two plans, providing information and metrics to assess their similarity. In addition to performing direct comparisons (e.g. demographics, ROI volumes, number of segments, total beam-on time), the tool computes and presents histograms of derived metrics (e.g. step-and-shoot segment field sizes, segment average leaf gaps). Such metrics were investigatedmore » for their ability to predict that an online-adapted plan reasonably similar to a baseline plan where deliverability has already been established. Results: In the realm of online-adaptive planning, comparing ROI volumes offers a sanity check to verify observations found during contouring. Beyond ROI analysis, it has been found that simply editing contours and re-optimizing to adapt treatment can produce a delivery that is substantially different than the baseline plan (e.g. number of segments increased by 31%), with no changes in optimization parameters and only minor changes in anatomy. Currently the tool can quickly identify large omissions or deviations from baseline expectations. As our online-adaptive patient population increases, we will continue to develop and refine quantitative acceptance criteria for adapted plans and relate them historical delivery QA measurements. Conclusion: The plan comparison tool is in clinical use and reports a wide range of comparison metrics, illustrating key differences between two plans. This independent check is accomplished in seconds and can be performed in parallel to other tasks in the online-adaptive workflow. Current use prevents large planning or delivery errors from occurring, and ongoing refinements will lead to increased assurance of plan quality.« less
Chromaticity calculations and code comparisons for x-ray lithography source XLS and SXLS rings
DOE Office of Scientific and Technical Information (OSTI.GOV)
Parsa, Z.
1988-06-16
This note presents the chromaticity calculations and code comparison results for the (x-ray lithography source) XLS (Chasman Green, XUV Cosy lattice) and (2 magnet 4T) SXLS lattices, with the standard beam optic codes, including programs SYNCH88.5, MAD6, PATRICIA88.4, PATPET88.2, DIMAD, BETA, and MARYLIE. This analysis is a part of our ongoing accelerator physics code studies. 4 figs., 10 tabs.
Building a virtual network in a community health research training program.
Lau, F; Hayward, R
2000-01-01
To describe the experiences, lessons, and implications of building a virtual network as part of a two-year community health research training program in a Canadian province. An action research field study in which 25 health professionals from 17 health regions participated in a seven-week training course on health policy, management, economics, research methods, data analysis, and computer technology. The participants then returned to their regions to apply the knowledge in different community health research projects. Ongoing faculty consultations and support were provided as needed. Each participant was given a notebook computer with the necessary software, Internet access, and technical support for two years, to access information resources, engage in group problem solving, share ideas and knowledge, and collaborate on projects. Data collected over two years consisted of program documents, records of interviews with participants and staff, meeting notes, computer usage statistics, automated online surveys, computer conference postings, program Web site, and course feedback. The analysis consisted of detailed review and comparison of the data from different sources. NUD*IST was then used to validate earlier study findings. The ten key lessons are that role clarity, technology vision, implementation staging, protected time, just-in-time training, ongoing facilitation, work integration, participatory design, relationship building, and the demonstration of results are essential ingredients for building a successful network. This study provides a descriptive model of the processes involved in developing, in the community health setting, virtual networks that can be used as the basis for future research and as a practical guide for managers.
The Practical Guide to Classroom Literacy Assessment
ERIC Educational Resources Information Center
Barone, Diane M.; Taylor, Joan M.
2006-01-01
Whether it is standardized test data, student journals, or informal classroom question and answer, assessments provide invaluable, ongoing diagnostic information for making key instructional decisions. In this engaging and comprehensive resource, the authors demonstrate practical ways for embedding test preparation into teaching by integrating…
Computational Exposure Science: An Emerging Discipline to Support 21st-Century Risk Assessment
Background: Computational exposure science represents a frontier of environmental science that is emerging and quickly evolving.Objectives: In this commentary, we define this burgeoning discipline, describe a framework for implementation, and review some key ongoing research elem...
Report #2005-P-00007, February 17, 2005. We asked stakeholders to define stewardship, list motivators and obstacles to participating in stewardship programs, and outline key roles for EPA to play to foster participating in environmental stewardship.
Adaptive governance to promote ecosystem services in urban green spaces
Managing urban green space as part of an ongoing social-ecological transformationposes novel governance issues, particularly in post-industrial settings. Urban green spaces operate as small-scale nodes in larger networks of ecological reserves that provide and maintain key ecosys...
NASA Astrophysics Data System (ADS)
Allal, Djamel
2009-01-01
A bilateral comparison subsequent to key comparison CCEM.RF-K9 was decided between VNIIFTRI and PTB. It was registered into the BIPM KCDB under the identifier CCEM.RF-K9.1. The results of this comparison were gathered by the pilot laboratory of comparison CCEM.RF-K9, the LNE, and a very good agreement was found between the two participants. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Gavrilkin, V.; Prokopenko, L.; Bakovec, N.; Zolotorevich, E.; Suvorov, V.; Ovchinnikov, Yu; Pilishvili, T.; Buleishvili, M.; Zhasanbaeva, B.; Aytzhatova, G.; Ticona, G.; Vyskocil, L.
2015-01-01
The COOMET.QM-K36 key comparison 'Electrolytic conductivity: 0.5 S/m' is a comparison in the field of electrolytic conductivity measurements conducted by COOMET and carried out in 2012. It used a solution of KCl in water and the results are connected to those of the CCQM key comparison CCQM-K36.a through common participation of VNIIFTRI (Russia), SMU (Slovakia) and Ukrmetrteststandart (Ukraine). The purpose of this key comparison was to establish the equivalence of measurements of electrolytic conductivity performed at the National Metrology Institutes of COOMET member states for the value of 0.5 S/m. The results can be used to support the CMCs claims over the range of 0.1 S/m to 1.3 S/m. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
2012-01-01
Background Reducing low-density lipoprotein cholesterol (LDL-C) is associated with reduced risk for major coronary events. Despite statin efficacy, a considerable proportion of statin-treated hypercholesterolemic patients fail to reach therapeutic LDL-C targets as defined by guidelines. This study compared the efficacy of ezetimibe added to ongoing statins with doubling the dose of ongoing statin in a population of Taiwanese patients with hypercholesterolemia. Methods This was a randomized, open-label, parallel-group comparison study of ezetimibe 10 mg added to ongoing statin compared with doubling the dose of ongoing statin. Adult Taiwanese hypercholesterolemic patients not at optimal LDL-C levels with previous statin treatment were randomized (N = 83) to ongoing statin + ezetimibe (simvastatin, atorvastatin or pravastatin + ezetimibe at doses of 20/10, 10/10 or 20/10 mg) or doubling the dose of ongoing statin (simvastatin 40 mg, atorvastatin 20 mg or pravastatin 40 mg) for 8 weeks. Percent change in total cholesterol, LDL-C, high-density lipoprotein cholesterol (HDL-C) and triglycerides, and specified safety parameters were assessed at 4 and 8 weeks. Results At 8 weeks, patients treated with statin + ezetimibe experienced significantly greater reductions compared with doubling the statin dose in LDL-C (26.2% vs 17.9%, p = 0.0026) and total cholesterol (20.8% vs 12.2%, p = 0.0003). Percentage of patients achieving treatment goal was greater for statin + ezetimibe (58.6%) vs doubling statin (41.2%), but the difference was not statistically significant (p = 0.1675). The safety and tolerability profiles were similar between treatments. Conclusion Ezetimibe added to ongoing statin therapy resulted in significantly greater lipid-lowering compared with doubling the dose of statin in Taiwanese patients with hypercholesterolemia. Studies to assess clinical outcome benefit are ongoing. Trial registration Registered at ClinicalTrials.gov: NCT00652327 PMID:22621316
Burns, D T; Kessler, C; O'Brien, M; Minniti, R
2012-01-01
A key comparison has been made between the air-kerma standards of the NIST, USA and the BIPM in the medium-energy x-ray range. The results show the standards to be in agreement at the level of the standard uncertainty of the comparison of 3.8 parts in 10 3 , except at 250 kV where the difference is 1.5 times the standard uncertainty. The results are analysed and presented in terms of degrees of equivalence, suitable for entry in the BIPM key comparison database.
Report on the bilateral comparison between BIM (Bulgaria) and VSL (The Netherlands)
NASA Astrophysics Data System (ADS)
Dekker, Paul; Kunova, Angela; Dierikx, Erik
2017-01-01
A bilateral comparison has been organized between VSL, The Netherlands and BIM, Bulgaria in the field of spectral regular transmittance measurements. This comparison is registered as EURAMET project nr. 1073 and EURAMET.PR-K6.2 in the BIPM key comparison database. The aim of the comparison is to demonstrate the improvement of calibration measurement capabilities of BIM in this working field. If this comparison is successful, i.e. the results support the claimed improvement in uncertainties, the improved CMC's for BIM will be included in Appendix C of the CIPM mutual recognition arrangement (MRA). The results of this comparison are linked to key comparison CCPR K6. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCPR, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Tonina, A.; Currás, M.; Navarro, M.
2014-01-01
The CIPM MRA states that its technical basis is a set of results obtained in a course of time through key comparisons carried out by the Consultative Committees of the CIPM, the BIPM and the Regional Metrology Organizations (RMOs). As part of this process, INTI (Argentina) has participated in several key and supplementary comparisons. By means of procedures for linking key comparison data, a bilateral comparison would help to provide assurance of equality in measurements between the participating laboratories. With this end, the comparison SIM.EM-S9.b of 1 ohm and 10 kiloohm standard resistors of INIMET (Cuba) and INTI was carried out from March to October 2012. The obtained results were very good. They show that the resistance standards maintained by INTI and INIMET were equivalent, within their combined uncertainties, on the mean date of the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by SIM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Developing leadership talent in healthcare organizations.
Wells, Wendy; Hejna, William
2009-01-01
Effective initiatives for developing and retaining leadership talent are built around five supporting elements: Identification of key leader competencies. Effective job design. A strong focus on leadership recruitment, development, and retention. Leadership training and development throughout all levels of the organization. Ongoing leadership assessment and performance management.
School Leadership in the Caribbean: Perceptions, Practices, Paradigms
ERIC Educational Resources Information Center
Miller, Paul, Ed.
2013-01-01
Successful school leadership is an issue currently being debated up and down Caribbean territories. Key issues in the ongoing debate include: students' outcomes and participation in the regional Caribbean Secondary Examinations (CSEC); teacher recruitment and retention; teacher training and continuing professional development (upgrading); and…
20 CFR 416.919s - Authorizing and monitoring the consultative examination.
Code of Federal Regulations, 2011 CFR
2011-04-01
...) A process for orientation, training, and review of new consultative examination providers, with.... (7) procedures for the ongoing review of consultative examination results to ensure compliance with...) Procedures for evaluating claimant reactions to key providers; and (11) A program of systematic, onsite...
Six Key Principles for Music Assessment
ERIC Educational Resources Information Center
Hale, Connie L.; Green, Susan K.
2009-01-01
Evaluating students' performance and measuring growth are ongoing foundational activities in the educational process. This article evolved from conversations between the authors about essential information that preservice teachers need to be able to assess their students fairly and effectively. Although the authors' expertise is in different…
DOE Office of Scientific and Technical Information (OSTI.GOV)
Ogilvie, Jennifer P.
Photosystem II (PSII) is the only known natural enzyme that uses solar energy to split water, making the elucidation of its design principles critical for our fundamental understanding of photosynthesis and for our ability to mimic PSII’s remarkable properties. This report discusses progress towards addressing key open questions about the PSII RC. It describes new spectroscopic methods that were developed to answer these questions, and summarizes the outcomes of applying these methods to study the PSII RC. Using 2D electronic spectroscopy and 2D electronic Stark spectroscopy, models for the PSII RC were tested and refined. Work is ongoing to usemore » the collected data to elucidate the charge separation mechanism in the PSII RC. Coherent dynamics were also observed in the PSII RC for the first time. Through extensive characterization and modeling we have assigned these coherences as vibronic in nature, and believe that they reflect resonances between key vibrational pigment modes and electronic energy gaps that may facilitate charge separation. Work is ongoing to definitively test the functional relevance of electronic-vibrational resonances.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fleming, P. A.; van Wingerden, J. W.; Wright, A. D.
2011-12-01
This paper presents the structure of an ongoing controller comparison experiment at NREL's National Wind Technology Center; the design process for the two controllers compared in this phase of the experiment, and initial comparison results obtained in field-testing. The intention of the study is to demonstrate the advantage of using modern multivariable methods for designing control systems for wind turbines versus conventional approaches. We will demonstrate the advantages through field-test results from experimental turbines located at the NWTC. At least two controllers are being developed side-by-side to meet an incrementally increasing number of turbine load-reduction objectives. The first, a multiplemore » single-input, single-output (m-SISO) approach, uses separately developed decoupled and classicially tuned controllers, which is, to the best of our knowledge, common practice in the wind industry. The remaining controllers are developed using state-space multiple-input and multiple-output (MIMO) techniques to explicity account for coupling between loops and to optimize given known frequency structures of the turbine and disturbance. In this first publication from the study, we present the structure of the ongoing controller comparison experiment, the design process for the two controllers compared in this phase, and initial comparison results obtained in field-testing.« less
NASA Astrophysics Data System (ADS)
Dobrowolska, D.; Kosterov, A.
2016-01-01
This is the final report for regional key comparison COOMET.AUV.A-K5 on the pressure calibration of laboratory standard microphones in the frequency range from 2 Hz to 10 kHz. Two laboratories—Central Office of Measures (GUM)—the national metrology institute for Poland and the State Enterprise Scientific-Research Institute for Metrology of Measurement and Control Systems (DP NDI Systema)— the designated institute for acoustics in Ukraine took part in this comparison with the GUM as a pilot. One travelling type LS1P microphone was circulated to the participants and results in the form of regular calibration certificates were collected. The results of the DP NDI Systema obtained in this comparison were linked to the CCAUV.A-K5 key comparison through the joint participation of the GUM. The degrees of equivalence were computed for DP NDI Systema with respect to the CCAUV.A-K5 key comparison reference value. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCAUV, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Messinger, Lauren B.; Alford, Connie E.; Csokmay, John M.; Henne, Melinda B.; Mumford, Sunni L.; Segars, James H.; Armstrong, Alicia Y.
2016-01-01
Objective To compare cost and efficacy of tubal anastomosis to in vitro fertilization (IVF) in women who desired fertility after a tubal ligation. Design Cost-effectiveness analysis. Setting Not applicable. Patient(s) Not applicable. Intervention(s) Not applicable. Main Outcome Measure(s) Cost per ongoing pregnancy. Result(s) Cost per ongoing pregnancy for women after tubal anastomosis ranged from $16,446 to $223,482 (2014 USD), whereas IVF ranged from $32,902 to $111,679 (2014 USD). Across maternal age groups <35 and 35–40, years tubal anastomosis was more cost effective than IVF for ongoing pregnancy. Sensitivity analyses validated these findings across a wide range of ongoing pregnancy probabilities as well as costs per procedure. Conclusion(s) Tubal anastomosis was the most cost-effective approach for most women less than 41 years of age, whereas IVF was the most cost-effective approach for women aged ≥41 years who desired fertility after tubal ligation. A model was created that can be modified based on cost and success rates in individual clinics for improved patient counseling. PMID:26006734
Messinger, Lauren B; Alford, Connie E; Csokmay, John M; Henne, Melinda B; Mumford, Sunni L; Segars, James H; Armstrong, Alicia Y
2015-07-01
To compare cost and efficacy of tubal anastomosis to in vitro fertilization (IVF) in women who desired fertility after a tubal ligation. Cost-effectiveness analysis. Not applicable. Not applicable. Not applicable. Cost per ongoing pregnancy. Cost per ongoing pregnancy for women after tubal anastomosis ranged from $16,446 to $223,482 (2014 USD), whereas IVF ranged from $32,902 to $111,679 (2014 USD). Across maternal age groups <35 and 35-40, years tubal anastomosis was more cost effective than IVF for ongoing pregnancy. Sensitivity analyses validated these findings across a wide range of ongoing pregnancy probabilities as well as costs per procedure. Tubal anastomosis was the most cost-effective approach for most women less than 41 years of age, whereas IVF was the most cost-effective approach for women aged ≥41 years who desired fertility after tubal ligation. A model was created that can be modified based on cost and success rates in individual clinics for improved patient counseling. Copyright © 2015 American Society for Reproductive Medicine. All rights reserved.
Time course of ongoing activity during neuritis and following axonal transport disruption.
Satkeviciute, Ieva; Goodwin, George; Bove, Geoffrey M; Dilley, Andrew
2018-05-01
Local nerve inflammation (neuritis) leads to ongoing activity and axonal mechanical sensitivity (AMS) along intact nociceptor axons and disrupts axonal transport. This phenomenon forms the most feasible cause of radiating pain, such as sciatica. We have previously shown that axonal transport disruption without inflammation or degeneration also leads to AMS but does not cause ongoing activity at the time point when AMS occurs, despite causing cutaneous hypersensitivity. However, there have been no systematic studies of ongoing activity during neuritis or noninflammatory axonal transport disruption. In this study, we present the time course of ongoing activity from primary sensory neurons following neuritis and vinblastine-induced axonal transport disruption. Whereas 24% of C/slow Aδ-fiber neurons had ongoing activity during neuritis, few (<10%) A- and C-fiber neurons showed ongoing activity 1-15 days following vinblastine treatment. In contrast, AMS increased transiently at the vinblastine treatment site, peaking on days 4-5 (28% of C/slow Aδ-fiber neurons) and resolved by day 15. Conduction velocities were slowed in all groups. In summary, the disruption of axonal transport without inflammation does not lead to ongoing activity in sensory neurons, including nociceptors, but does cause a rapid and transient development of AMS. Because it is proposed that AMS underlies mechanically induced radiating pain, and a transient disruption of axonal transport (as previously reported) leads to transient AMS, it follows that processes that disrupt axonal transport, such as neuritis, must persist to maintain AMS and the associated symptoms. NEW & NOTEWORTHY Many patients with radiating pain lack signs of nerve injury on clinical examination but may have neuritis, which disrupts axonal transport. We have shown that axonal transport disruption does not induce ongoing activity in primary sensory neurons but does cause transient axonal mechanical sensitivity. The present data complete a profile of key axonal sensitivities following axonal transport disruption. Collectively, this profile supports that an active peripheral process is necessary for maintained axonal sensitivities.
Simulation of Guided Wave Interaction with In-Plane Fiber Waviness
NASA Technical Reports Server (NTRS)
Leckey, Cara A. C.; Juarez, Peter D.
2016-01-01
Reducing the timeline for certification of composite materials and enabling the expanded use of advanced composite materials for aerospace applications are two primary goals of NASA's Advanced Composites Project (ACP). A key a technical challenge area for accomplishing these goals is the development of rapid composite inspection methods with improved defect characterization capabilities. Ongoing work at NASA Langley is focused on expanding ultrasonic simulation capabilities for composite materials. Simulation tools can be used to guide the development of optimal inspection methods. Custom code based on elastodynamic finite integration technique is currently being developed and implemented to study ultrasonic wave interaction with manufacturing defects, such as in-plane fiber waviness (marcelling). This paper describes details of validation comparisons performed to enable simulation of guided wave propagation in composites containing fiber waviness. Simulation results for guided wave interaction with in-plane fiber waviness are also discussed. The results show that the wavefield is affected by the presence of waviness on both the surface containing fiber waviness, as well as the opposite surface to the location of waviness.
Immune correlates of protection for dengue: State of the art and research agenda.
Katzelnick, Leah C; Harris, Eva
2017-08-24
Dengue viruses (DENV1-4) are mosquito-borne flaviviruses estimated to cause up to ∼400 million infections and ∼100 million dengue cases each year. Factors that contribute to protection from and risk of dengue and severe dengue disease have been studied extensively but are still not fully understood. Results from Phase 3 vaccine efficacy trials have recently become available for one vaccine candidate, now licensed for use in several countries, and more Phase 2 and 3 studies of additional vaccine candidates are ongoing, making these issues all the more urgent and timely. At the "Summit on Dengue Immune Correlates of Protection", held in Annecy, France, on March 8-9, 2016, dengue experts from diverse fields came together to discuss the current understanding of the immune response to and protection from DENV infection and disease, identify key unanswered questions, discuss data on immune correlates and plans for comparison of results across assays/consortia, and propose a research agenda for investigation of dengue immune correlates, all in the context of both natural infection studies and vaccine trials. Copyright © 2017.
Simulation of guided wave interaction with in-plane fiber waviness
NASA Astrophysics Data System (ADS)
Leckey, Cara A. C.; Juarez, Peter D.
2017-02-01
Reducing the timeline for certification of composite materials and enabling the expanded use of advanced composite materials for aerospace applications are two primary goals of NASA's Advanced Composites Project (ACP). A key a technical challenge area for accomplishing these goals is the development of rapid composite inspection methods with improved defect characterization capabilities. Ongoing work at NASA Langley is focused on expanding ultrasonic simulation capabilities for composite materials. Simulation tools can be used to guide the development of optimal inspection methods. Custom code based on elastodynamic finite integration technique is currently being developed and implemented to study ultrasonic wave interaction with manufacturing defects, such as in-plane fiber waviness (marcelling). This paper describes details of validation comparisons performed to enable simulation of guided wave propagation in composites containing fiber waviness. Simulation results for guided wave interaction with in-plane fiber waviness are also discussed. The results show that the wavefield is affected by the presence of waviness on both the surface containing fiber waviness, as well as the opposite surface to the location of waviness.
Methodology or method? A critical review of qualitative case study reports
Hyett, Nerida; Kenny, Amanda; Dickson-Swift, Virginia
2014-01-01
Despite on-going debate about credibility, and reported limitations in comparison to other approaches, case study is an increasingly popular approach among qualitative researchers. We critically analysed the methodological descriptions of published case studies. Three high-impact qualitative methods journals were searched to locate case studies published in the past 5 years; 34 were selected for analysis. Articles were categorized as health and health services (n=12), social sciences and anthropology (n=7), or methods (n=15) case studies. The articles were reviewed using an adapted version of established criteria to determine whether adequate methodological justification was present, and if study aims, methods, and reported findings were consistent with a qualitative case study approach. Findings were grouped into five themes outlining key methodological issues: case study methodology or method, case of something particular and case selection, contextually bound case study, researcher and case interactions and triangulation, and study design inconsistent with methodology reported. Improved reporting of case studies by qualitative researchers will advance the methodology for the benefit of researchers and practitioners. PMID:24809980
Reinforcer Control by Comparison-Stimulus Color and Location in a Delayed Matching-to-Sample Task
ERIC Educational Resources Information Center
Alsop, Brent; Jones, B. Max
2008-01-01
Six pigeons were trained in a delayed matching-to-sample task involving bright- and dim-yellow samples on a central key, a five-peck response requirement to either sample, a constant 1.5-s delay, and the presentation of comparison stimuli composed of red on the left key and green on the right key or vice versa. Green-key responses were…
Burns, D T; Kessler, C; O’Brien, M; Minniti, R
2017-01-01
A key comparison has been made between the air-kerma standards of the NIST, USA and the BIPM in the medium-energy x–ray range. The results show the standards to be in agreement at the level of the standard uncertainty of the comparison of 3.8 parts in 103, except at 250 kV where the difference is 1.5 times the standard uncertainty. The results are analysed and presented in terms of degrees of equivalence, suitable for entry in the BIPM key comparison database. PMID:28966399
Assessing the Effectiveness of the International Counterproliferation Program
2011-01-01
a box labeled “Ongoing needs assessment.” Within this box are the two key planning actions that contribute to this type of assessment: identification ...nation, all participating countries tend to receive a fairly standardized set of courses. This course lineup is determined largely by the ICP
GOALS AND CURRENT RESEARCH OF EPA'S STREAM RESTORATION RESEARCH PROGRAM
The US EPA is involved in ongoing research on stream and riparian restoration. This presentation is designed to discuss current EPA research efforts, identify key issues in the science and practice of stream restoration, and to help frame a future National Research Council study...
What's wrong with novel ecosystems, really?
USDA-ARS?s Scientific Manuscript database
The novel ecosystems concept has gained much traction in the restoration community. It has also drawn the ire of several prominent ecologists and is the focus of an ongoing debate. We consider three key aspects of this debate: irreversible thresholds, non-native species, and the hybrid state. Irreve...
KEY COMPARISON Final report on international comparison CCQM-K71: Measurement of stack gas
NASA Astrophysics Data System (ADS)
Nieuwenkamp, G.; van der Veen, A. M. H.; Wessel, R. M.; Qiao, Han; Oh, Sang-Hyub; Kim, Byung-Moon; Kim, Kwang-Sub; Pérez Castorena, Alejandro; Ramírez Nambo, Carlos; Koelliker Delgado, Jorge; Serrano Caballero, Victor M.; Rangel Murillo, Francisco; Avila Salas, Manuel de Jesus; Dias, Florbela; Baptista, Gonçalo; Konopelko, L. A.; Kustikov, Y. A.; Pankratov, V. V.; Selyukov, D. N.; Balandovich, V. S.; Vishnyakov, I. M.; Pavlov, M. V.; Maltsev, M. A.; Botha, Angelique; Valkova, Miroslava; Stovcik, Viliam; Musil, Stanislav; Milton, M. J. T.; Uprichard, I. J.; Vargha, G. M.; Guenther, F.; Gameson, L.; da Cunha, V.
2010-01-01
Industrial stack gas emission measurements are important for process control, control of air pollution, and for implementing legislation regarding carbon dioxide emission rights. Measurements are typically performed using a range of process analysers for carbon monoxide (CO), carbon dioxide (CO2), nitrogen oxides (NOx), sulphur dioxide (SO2) and miscellaneous hydrocarbons. The calibration of these analysers is often performed using a series of binary mixtures of each component in nitrogen. For reasons of efficiency as well as a better match with true stack gas, the use of multi-component mixtures for this purpose would be preferred. The aim of this key comparison is to evaluate the measurement capabilities of national metrology institutes for carbon monoxide, carbon dioxide, nitrogen monoxide, sulphur dioxide and propane in nitrogen. Ten laboratories participated in the key comparison and one in the associated study. The key comparison reference value is based on the gravimetric preparation data. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Ojanen, M.; Shpak, M.; Kärhä, P.; Leecharoen, R.; Ikonen, E.
2009-01-01
A bilateral comparison of the spectral irradiance scales between MIKES (Finland) and NIMT (Thailand) was carried out at 22 wavelengths between 290 nm and 900 nm. MIKES acted as the pilot and link to the results of the key comparison CCPR-K1.a. The spectral irradiance values measured by NIMT generally agree with the key comparison reference value within the expanded uncertainty. The only exceptions are results at wavelengths 300 nm, 450 nm and 500 nm, where the ratios between the degree of equivalence (DoE) and the expanded uncertainty of DoE (k = 2) are 1.0, 1.4 and 1.2, respectively. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCPR, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Zhou, Z.; Han, Q.; Wang, D.; Macé, T.; Kipphardt, H.; Maiwald, M.; Tuma, D.; Uehara, S.; Akima, D.; Shimosaka, T.; Jung, J.; Oh, S.-H.; van der Veen, A.; van Wijk, J. I. T.; Ziel, P. R.; Konopelko, L.; Valkova, M.; Mogale, David M.; Botha, A.; Brewer, P.; Murugan, A.; Doval Minnaro, M.; Miller, M.; Guenther, F.; Kelly, M. E.
2016-01-01
This key comparison aims to assess the capabilities of the participants to determine the amount-of-substance fraction oxygen in nitrogen. The GAWG has classified this as a track B comparison, due to the unexpected 50 μmol/mol argon mole fraction content of the transfer standards, which effects the achievable performance of some measurement techniques such a GC-TCD. The separation of oxygen and argon is challenging, and not all systems in use are equally well designed for it. As this analytical challenge due to a substantial fraction of argon in the transfer standards became a reality, the Gas Analysis Working Group (GAWG) decided to qualify this key comparison as a regular key comparison and not as a core comparison, which may be used to support calibration and measurement capabilities (CMCs) for oxygen in nitrogen, or for oxygen in nitrogen mixtures containing argon only (see also the section on support to CMCs). Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Evaluation of an Ongoing Diabetes Group Medical Visit in a Family Medicine Practice.
Cunningham, Amy T; Delgado, David J; Jackson, Joseph D; Crawford, Albert G; Jabbour, Serge; Lieberthal, Robert D; Diaz, Victor; LaNoue, Marianna
2018-01-01
Group medical visits (GMVs), which combine 1-on-1 clinical consultations and group self-management education, have emerged as a promising vehicle for supporting type 2 diabetes management in primary care. However, few evaluations exist of ongoing diabetes GMVs embedded in medical practices. This study used a quasi-experimental design to evaluate diabetes GMV at a large family medicine practice. We examined program attendance and attrition, used propensity score matching to create a matched comparison group, and compared participants and the matched group on clinical, process of care, and utilization outcomes. GMV participants (n = 230) attended an average of 1 session. Participants did not differ significantly from the matched comparison group (n = 230) on clinical, process of care or utilization outcomes. The diabetes GMV was not associated with improvements in outcomes. Further studies should examine diabetes GMV implementation challenges to enhance their effectiveness in everyday practice. © Copyright 2018 by the American Board of Family Medicine.
NASA Astrophysics Data System (ADS)
Sobina, E.; Zimathis, A.; Prinz, C.; Emmerling, F.; Unger, W.; de Santis Neves, R.; Galhardo, C. E.; De Robertis, E.; Wang, H.; Mizuno, K.; Kurokawa, A.
2016-01-01
CCQM key comparison K-136 Measurement of porosity properties (specific adsorption, BET specific surface area, specific pore volume and pore diameter) of nanoporous Al2O3 has been performed by the Surface Analysis Working Group (SAWG) of the Consultative Committee for Amount of Substance (CCQM). The objective of this key comparison is to compare the equivalency of the National Metrology Institutes (NMIs) and Designated Institutes (DIs) for the measurement of specific adsorption, BET specific surface area, specific pore volume and pore diameter) of nanoporous substances (sorbents, catalytic agents, cross-linkers, zeolites, etc) used in advanced technology. In this key comparison, a commercial sorbent (aluminum oxide) was supplied as a sample. Five NMIs participated in this key comparison. All participants used a gas adsorption method, here nitrogen adsorption at 77.3 K, for analysis according to the international standards ISO 15901-2 and 9277. In this key comparison, the degrees of equivalence uncertainties for specific adsorption, BET specific surface area, specific pore volume and pore diameter was established. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Evaluation of the Introduction of an e-Health Skills Component for Dietetics Students.
Rollo, Megan E; Collins, Clare E; MacDonald-Wicks, Lesley
2017-11-01
Appropriate and effective use of technology within practice is a key competency outlined in Australian dietetics training standards. An e-health skills component (lecture and workshop) was introduced to undergraduate students enrolled in an Australian nutrition and dietetics program. The lecture orientated students to key e-health terms and concepts relating to telehealth and m-health technologies, while the workshop provided an opportunity to apply knowledge. The workshop consisted of four stations with activities relating to (1) orientation to telehealth equipment; (2) comparison of dietetic consultation components completed in person versus remotely via video call; (3) quality assessment of mobile apps; and (4) exploration of advantages and disadvantages, and the ethical, security, and privacy issues relating to use of e-health technologies in dietetic practice. Student experience of the training was evaluated via questionnaire. Forty-five students (62.2% aged ≤19-24 years, 86.7% female) completed the survey. Following the workshop, the level of understanding relating to each key e-health concept improved significantly (p < 0.001). The aspects relating to the impact and need for initial training and ongoing professional education to support the use of e-health technologies within dietetic practice were rated a high level of importance by most students (78-80%). The majority of students (93.3% to 97.8%) reported a positive experience at each of the four workshop stations, with "informative" the most common word selected to rate each station (37.8% to 44.4% of students across the four stations). The introduction of an e-health skills component resulted in an improved understanding of concepts for using these technologies. These findings provide preliminary support for integration of further e-health training within the dietetics program.
A School-Based Quality Improvement Program.
ERIC Educational Resources Information Center
Rappaport, Lewis A.
1993-01-01
As one Brooklyn high school discovered, quality improvement begins with administrator commitment and participants' immersion in the literature. Other key elements include ongoing training of personnel involved in the quality-improvement process, tools such as the Deming Cycle (plan-do-check-act), voluntary and goal-oriented teamwork, and a worthy…
The Management Development Needs of Front-Line Managers: Voices from the Field.
ERIC Educational Resources Information Center
Longenecker, Clinton O.; Neubert, Mitchell
2003-01-01
A survey of 524 managers identified key practices to improve performance in a changing environment: clarifying roles, goals, and expectations; ongoing performance evaluation, feedback, and coaching; mentoring; challenging assignments; formal career planning; customer contact; cross-training; and 360-degree feedback. (Contains 31 references.) (SK)
Asia Society's Ongoing Chinese Language Initiatives
ERIC Educational Resources Information Center
Livaccari, Chris; Wang, Jeff
2009-01-01
Asia Society remains committed to promoting the teaching and learning of Chinese in American schools as an integral part of the broader agenda of building students' global competency, the key goal of its Partnership for Global Learning. Under the leadership of Asia Society's new Vice President for Education Tony Jackson and with continuing…
Magnet Marketing: Drawing Prospects to Your Center Until They Enroll.
ERIC Educational Resources Information Center
Wassom, Julie
1999-01-01
The key to achieving effective marketing of centers and services is to make messages creative, consistent, and continual. Creative marketing involves creating an awareness of the program. A consistent, identifiable image will create program recognition. Effective, continual marketing utilizes a mix of marketing methods on an ongoing basis to…
A Multiyear Investigation of Combating Bullying in Middle School: Stakeholder Perspectives
ERIC Educational Resources Information Center
Shriberg, David; Burns, Mallory; Desai, Poonam; Grunewald, Stephanie; Pitt, Rachel
2015-01-01
Working collaboratively to address bullying among middle school students is an ongoing challenge. This study used participatory action research to collaborate with key stakeholders within a middle school to identify needs and implement more effective practices. Extensive qualitative and quantitative data are presented, along with process…
Conflict, Militarization, and Their After-Effects: Key Challenges for TESOL
ERIC Educational Resources Information Center
Nelson, Cynthia D.; Appleby, Roslyn
2015-01-01
Skyrocketing military spending, ongoing military conflicts, and human displacement worldwide have significant consequences for the teaching and learning of English. TESOL increasingly requires a robust research base that can provide informed, critical guidance in preparing English language teachers for work in and near conflict zones, for teaching…
Preparing School Leaders to Work with and in Community
ERIC Educational Resources Information Center
FitzGerald, Anne Marie; Militello, Matthew
2016-01-01
We used Q methodology, a form of factor analysis, to explore and establish correlations across the perceptions of key stakeholders (i.e., deans, faculty members, doctoral students) about how doctoral programs in educational leadership engage in work with diverse communities. Four distinct viewpoints emerged suggesting the ongoing need to: develop…
The Validity of Two Education Requirement Measures
ERIC Educational Resources Information Center
van der Meer, Peter H.
2006-01-01
In this paper we investigate the validity of two education requirement measures. This is important because a key part of the ongoing discussion concerning overeducation is about measurement. Thanks to the Dutch Institute for Labour Studies, we have been given a unique opportunity to compare two education requirement measures: first, Huijgen's…
Key Emerging Technologies for Elementary and Secondary Education
ERIC Educational Resources Information Center
Johnson, Laurence F.; Levine, Alan; Smith, Rachel S.; Haywood, Keene
2010-01-01
The Horizon Report series is the most visible outcome of the New Media Consortium's Horizon Project, an ongoing research effort that identifies and describes emerging technologies likely to have a large impact on teaching, learning, research, or creative expression within education around the globe. The report examines emerging technologies for…
Key Emerging Technologies for Elementary and Secondary Education
ERIC Educational Resources Information Center
Johnson, Laurence F.; Levine, Alan; Smith, Rachel S.; Haywood, Keene
2010-01-01
The "Horizon Report" series is the most visible outcome of the New Media Consortium's Horizon Project, an ongoing research effort that identifies and describes emerging technologies likely to have a large impact on teaching, learning, research, or creative expression within education around the globe. The report examines emerging technologies for…
Skills for Innovation and Research
ERIC Educational Resources Information Center
OECD Publishing (NJ3), 2011
2011-01-01
Innovation holds the key to ongoing improvements in living standards, as well as to solving pressing social challenges. Skilled people play a crucial role in innovation through the new knowledge they generate, how they adopt and develop existing ideas, and through their ability to learn new competencies and adapt to a changing environment. This…
Palomar College: A Technological Transformation.
ERIC Educational Resources Information Center
Halttunen, Lynda Gavigan
2002-01-01
Offers advice for colleges intending to undergo software conversions, asserting that sufficient resources are key to a smooth process. Describes the conversion process at Palomar College (California) in 1997, when Palomar purchased PeopleSoft enterprise-wide software in response to Y2K compliance issues. Stresses the ongoing need for training and…
California Colleges and Universities Collaborate to Support Student Mental Health
ERIC Educational Resources Information Center
Woodbridge, Michelle W.; Goldweber, Asha; Yu, Jennifer; Golan, Shari; Stein, Bradley D.
2014-01-01
One key objective of California's Prevention and Early Intervention (PEI) Student Mental Health (SMH) initiative funded under Proposition 63 is to establish a formal process for ongoing collaboration between higher education systems and county mental health, as well as to increase collaboration among higher education campuses to improve student…
This poster provides an overview of three key lines of ongoing work at EPA/ORD/NCEA-CIN: Provisional Peer-Reviewed Toxicity Values (PPRTVs), Alternative Methods in Human Health Risk Assessment, and the RapidTox Dashboard collaboration.
Market Demand for Sustainability in Management Education
ERIC Educational Resources Information Center
Gitsham, Matthew; Clark, Timothy S.
2014-01-01
Purpose: This paper aims to contribute to the ongoing debate about the relevance of sustainability in management education through exploration of the needs and expectations of a key group of business schools' stakeholders--senior executives of leading corporations. Design/methodology/approach: The paper presents findings from a survey regarding…
The Potential Contribution of Intermediary Organizations for Implementation of School Mental Health
ERIC Educational Resources Information Center
Corcoran, Tim; Rowling, Louise; Wise, Marilyn
2015-01-01
Questions persist regarding implementation of mental health promotion, prevention, and early intervention initiatives in schools. To date, attention has targeted the "Whats" and "Hows" in design and implementation. Ongoing clarification of "Who" the key proponents are working in this space receives less consideration.…
A Collaborative Professional Development Initiative Supporting Early Literacy Coaches
ERIC Educational Resources Information Center
Mraz, Maryann; Kissel, Brian; Algozzine, Bob; Babb, Julie; Foxworth, Kimberly
2011-01-01
Many believe that the key to translating research into successful practice lies in providing teachers with continuous professional development and ongoing coaching support. In this article, we provide an overview of the relevant coaching literature and describe 4 critical features of an evidence-based preschool literacy coaching model: the coach…
Final Report on the Key Comparison CCM.P-K4.2012 in Absolute Pressure from 1 Pa to 10 kPa
Ricker, Jacob; Hendricks, Jay; Bock, Thomas; Dominik, Pražák; Kobata, Tokihiko; Torres, Jorge; Sadkovskaya, Irina
2017-01-01
The report summarizes the Consultative Committee for Mass (CCM) key comparison CCM.P-K4.2012 for absolute pressure spanning the range of 1 Pa to 10 000 Pa. The comparison was carried out at six National Metrology Institutes (NMIs), including National Institute of Standards and Technology (NIST), Physikalisch-Technische Bundesanstalt (PTB), Czech Metrology Institute (CMI), National Metrology Institute of Japan (NMIJ), Centro Nacional de Metrología (CENAM), and DI Mendeleyev Institute for Metrology (VNIIM). The comparison was made via a calibrated transfer standard measured at each of the NMIs facilities using their laboratory standard during the period May 2012 to September 2013. The transfer package constructed for this comparison preformed as designed and provided a stable artifact to compare laboratory standards. Overall the participants were found to be statistically equivalent to the key comparison reference value. PMID:28216793
All about Eve: Secret Sharing using Quantum Effects
NASA Technical Reports Server (NTRS)
Jackson, Deborah J.
2005-01-01
This document discusses the nature of light (including classical light and photons), encryption, quantum key distribution (QKD), light polarization and beamsplitters and their application to information communication. A quantum of light represents the smallest possible subdivision of radiant energy (light) and is called a photon. The QKD key generation sequence is outlined including the receiver broadcasting the initial signal indicating reception availability, timing pulses from the sender to provide reference for gated detection of photons, the sender generating photons through random polarization while the receiver detects photons with random polarization and communicating via data link to mutually establish random keys. The QKD network vision includes inter-SATCOM, point-to-point Gnd Fiber and SATCOM-fiber nodes. QKD offers an unconditionally secure method of exchanging encryption keys. Ongoing research will focus on how to increase the key generation rate.
Comparison of Bottomless Lift Nets and Breder Traps for Sampling Salt-Marsh Nekton
Vegetated salt-marsh surfaces provide refuge, forage, and spawning habitat for estuarine nekton, yet are threatened by accelerating rates of sea-level rise in southern New England and elsewhere. Nekton responses to ongoing marsh surface changes need to be evaluated with effective...
NASA Astrophysics Data System (ADS)
Nagakura, H.; Richers, S.; Ott, C. D.; Iwakami, W.; Furusawa, S.; Sumiyoshi, K.; Yamada, S.; Matsufuru, H.; Imakura, A.
2016-10-01
We have developed a 7-dimensional Full Boltzmann-neutrino-radiation-hydrodynamical code and carried out ab-initio axisymmetric CCSNe simulations. I will talk about main results of our simulations and also discuss current ongoing projects.
The Comparison Of Dome And HMD Delivery Systems: A Case Study
NASA Technical Reports Server (NTRS)
Chen, Jian; Harm, Deborah L.; Loftin, R. Bowen; Tyalor, Laura C.; Leiss, Ernst L.
2002-01-01
For effective astronaut training applications, choosing the right display devices to present images is crucial. In order to assess what devices are appropriate, it is important to design a successful virtual environment for a comparison study of the display devices. We present a comprehensive system, a Virtual environment testbed (VET), for the comparison of Dome and Head Mounted Display (HMD) systems on an SGI Onyx workstation. By writing codelets, we allow a variety of virtual scenarios and subjects' information to be loaded without programming or changing the code. This is part of an ongoing research project conducted by the NASA / JSC.
Seismic and Infrasound Location
DOE Office of Scientific and Technical Information (OSTI.GOV)
Arrowsmith, Stephen J.; Begnaud, Michael L.
2014-03-19
This presentation includes slides on Signal Propagation Through the Earth/Atmosphere Varies at Different Scales; 3D Seismic Models: RSTT; Ray Coverage (Pn); Source-Specific Station Corrections (SSSCs); RSTT Conclusions; SALSA3D (SAndia LoS Alamos) Global 3D Earth Model for Travel Time; Comparison of IDC SSSCs to RSTT Predictions; SALSA3D; Validation and Model Comparison; DSS Lines in the Siberian Platform; DSS Line CRA-4 Comparison; Travel Time Δak135; Travel Time Prediction Uncertainty; SALSA3D Conclusions; Infrasound Data Processing: An example event; Infrasound Data Processing: An example event; Infrasound Location; How does BISL work?; BISL: Application to the 2013 DPRK Test; and BISL: Ongoing Research.
Final report on the key comparison CCM.P-K4.2012 in absolute pressure from 1 Pa to 10 kPa
NASA Astrophysics Data System (ADS)
Ricker, Jacob; Hendricks, Jay; Bock, Thomas; Dominik, Pražák; Kobata, Tokihiko; Torres, Jorge; Sadkovskaya, Irina
2017-01-01
The report summarizes the Consultative Committee for Mass (CCM) key comparison CCM.P-K4.2012 for absolute pressure spanning the range of 1 Pa to 10 000 Pa. The comparison was carried out at six National Metrology Institutes (NMIs), including National Institute of Standards and Technology (NIST), Physikalisch-Technische Bundesanstalt (PTB), Czech Metrology Institute (CMI), National Metrology Institute of Japan (NMIJ), Centro Nacional de Metrología (CENAM), and DI Mendeleyev Institute for Metrology (VNIIM). The comparison was made via a calibrated transfer standard measured at each of the NMIs facilities using their laboratory standard during the period May 2012 to September 2013. The transfer package constructed for this comparison preformed as designed and provided a stable artifact to compare laboratory standards. Overall the participants were found to be statistically equivalent to the key comparison reference value. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Fedchak, J. A.; Bock, Th; Jousten, K.
2014-01-01
This report describes the bilateral key comparison CCM.P-K3.1 between the National Institute of Standards and Technology (NIST) and Physikalisch-Technische Bundesanstalt (PTB) for absolute pressure in the range from 3 × 10-6 Pa to 9 × 10-4 Pa. This comparison was a follow-up to the comparison CCM.P-K3. Two ionization gauges and two spinning rotor gauges (SRGs) were used as the transfer standards for the comparison. The SRGs were used to compare the standards at a pressure of 9 × 10-4 Pa and to normalize the ionization gauge readings. The two ionization gauges were used to compare the standards in the pressure range of from 3 × 10-6 Pa to 3 × 10-4 Pa. Both laboratories used dynamic expansion chambers as standards in the comparison. The two labs showed excellent agreement with each other and with the CCM.P-K3 key comparison reference value (KCRV) over the entire range. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Kessler, C.; Burns, D.; Durný, N.
2018-01-01
A key comparison of the standards for air kerma of the Slovak Institute of Metrology (SMU), Slovakia and of the Bureau International des Poids et Mesures (BIPM) was carried out in the 60Co radiation beam of the BIPM in June 2017. The comparison result, evaluated as a ratio of the SMU and the BIPM standards for air kerma, is 1.0042 with a combined standard uncertainty of 2.7 × 10-3. The results for an indirect comparison made at the same time are consistent with the direct results at the level of 2 parts in 104. The results are analysed and presented in terms of degrees of equivalence, suitable for entry in the BIPM key comparison database. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Silva, H.; Monasterios, G.
2016-01-01
The first key comparison in microwave frequencies within the SIM (Sistema Interamericano de Metrología) region has been carried out. The measurands were the S-parameters of 50 ohm coaxial devices with Type-N connectors and were measured at 2 GHz, 9 GHz and 18 GHz. SIM.EM.RF-K5b.CL was the identification assigned and it was based on a parent CCEM key comparison named CCEM.RF-K5b.CL. For this reason, the measurements standards and their nominal values were selected accordingly, i.e. two one-port devices (a matched and a mismatched load) to cover low and high reflection coefficients and two attenuators (3dB and 20 dB) to cover low and high transmission coefficients. This key comparison has met the need for ensuring traceability in high-frequency measurements across America by linking SIM's results to CCEM. Six NMIs have participated in this comparison which was piloted by the Instituto Nacional de Tecnología Industrial (Argentina). A linking method of multivariate values was proposed and implemented in order to allow the linking of 2-dimensional results. KEY WORDS FOR SEARCH Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
DOE Office of Scientific and Technical Information (OSTI.GOV)
Fleming, P. A.; Van Wingerden, J. W.; Wright, A. D.
2012-01-01
In this paper we present results from an ongoing controller comparison study at the National Renewable Energy Laboratory's (NREL's) National Wind Technology Center (NWTC). The intention of the study is to demonstrate the advantage of using modern multivariable methods for designing control systems for wind turbines versus conventional approaches. We will demonstrate the advantages through field-test results from experimental turbines located at the NWTC. At least two controllers are being developed side-by-side to meet an incrementally increasing number of turbine load-reduction objectives. The first, a multiple single-input, single-output (m-SISO) approach, uses separately developed decoupled and classicially tuned controllers, which is,more » to the best of our knowledge, common practice in the wind industry. The remaining controllers are developed using state-space multiple-input and multiple-output (MIMO) techniques to explicity account for coupling between loops and to optimize given known frequency structures of the turbine and disturbance. In this first publication from the study, we present the structure of the ongoing controller comparison experiment, the design process for the two controllers compared in this phase, and initial comparison results obtained in field-testing.« less
This presentation will focus on MED's past and ongoing research in Lake Superior wetlands, and will include data on habitat, water quality, and biological condition of these systems. Comparisons of the condition of Lake Superior wetlands relative to those found around the Great ...
COMPARISON OF TWO PARTICLE-SIZE SPECTROMETERS FOR AMBIENT AEROSOL MEASUREMENTS. (R827354C002)
There is an ongoing debate on the question which size fraction of particles in ambient air may be responsible for human health effects observed in epidemiological studies. Since there is no single instrument available for the measurement of the particle-size distribution over ...
COMPARISON OF GEOCODING METHODS USED IN CASE-CONTROL STUDY OF AIR QUALITY AND BIRTH DEFECTS
Introduction: Accurate geocoding of maternal residence is critical to the success of an ongoing case-control study of exposure to five criteria air pollutants and the risk of selected birth defects in seven Texas counties between 1997 and 2000. The geocoded maternal residence a...
Nursing Distance Learning Course Comparison of Assignments and Examination Scores
ERIC Educational Resources Information Center
Mundine, Jennifer
2016-01-01
Nursing programs have embraced distance learning in their curricula, but discussion is ongoing about course assignments and grading criteria to increase examination scores in nursing distance learning courses. Because course examinations are a predictor of success on the postgraduate licensing examination (NCLEX-RN), the purpose of this study was…
Advanced CRM training for instructors and evaluators
NASA Technical Reports Server (NTRS)
Taggart, William R.
1991-01-01
It is seen that if the maximum operational benefit of crew resource management (CRM) is to be achieved, the evaluator group is the principal key and specialized training that is ongoing is necessary for this group. The training must be customized to fit the needs of a particular organization, and the training must address key topical issues that influence organizational dynamics. Attention is given to the use of video and full length scripted NASA research LOFTS, behavioral markers and debriefing skills, the importance of policy and written CRM standards, and line oriented simulations debriefing performance indicators.
NASA Technical Reports Server (NTRS)
Bennett, Gary L.; Brandhorst, Henry W., Jr.; Atkins, Kenneth L.
1991-01-01
In July 1989, President Bush announced his space exploration initiative of going back to the Moon to stay and then going to Mars. Building upon its ongoing research and technology base, NASA has established an exploration technology program to develop the technologies needed for piloted missions to the Moon and Mars. A key element for the flights and for the planned bases is power. The NASA research and technology program on space power encompasses power sources, energy storage, and power management.
An overview of key technology thrusts at Bell Helicopter Textron
NASA Technical Reports Server (NTRS)
Harse, James H.; Yen, Jing G.; Taylor, Rodney S.
1988-01-01
Insight is provided into several key technologies at Bell. Specific topics include the results of ongoing research and development in advanced rotors, methodology development, and new configurations. The discussion on advanced rotors highlight developments on the composite, bearingless rotor, including the development and testing of full scale flight hardware as well as some of the design support analyses and verification testing. The discussion on methodology development concentrates on analytical development in aeromechanics, including correlation studies and design application. New configurations, presents the results of some advanced configuration studies including hardware development.
Progress in satellite quantum key distribution
NASA Astrophysics Data System (ADS)
Bedington, Robert; Arrazola, Juan Miguel; Ling, Alexander
2017-08-01
Quantum key distribution (QKD) is a family of protocols for growing a private encryption key between two parties. Despite much progress, all ground-based QKD approaches have a distance limit due to atmospheric losses or in-fibre attenuation. These limitations make purely ground-based systems impractical for a global distribution network. However, the range of communication may be extended by employing satellites equipped with high-quality optical links. This manuscript summarizes research and development which is beginning to enable QKD with satellites. It includes a discussion of protocols, infrastructure, and the technical challenges involved with implementing such systems, as well as a top level summary of on-going satellite QKD initiatives around the world.
Mumusoglu, Sezcan; Ozbek, Irem Y; Sokmensuer, Lale K; Polat, Mehtap; Bozdag, Gurkan; Papanikolaou, Evangelos; Yarali, Hakan
2017-12-01
Not all euploid embryos implant, necessitating additional tools to select viable blastocysts in preimplantation genetic screening cycles. In this retrospective cohort study, 129 consecutive patients who underwent 129 single euploid blastocyst transfers in cryopreserved embryo transfer cycles were included. All embryos were individually cultured in a time-lapse incubator from intracytoplasmic sperm injection up to trophoectoderm biopsy. Twenty-three time-lapse morphokinetic variables were tested among patients with (n = 68) or without (n = 61) ongoing pregnancy. All 23 time-lapse morphokinetic variables, apart from duration of blastulation (tB-tSB), were comparable between patients with or without ongoing pregnancy. Duration of blastulation was significantly shorter in patients with ongoing pregnancy (8.1 ± 3.2 versus 9.5 ± 3.4 h; P = 0.014); shorter duration of blastulation remained an independent predictor for ongoing pregnancy, when tested by logistic regression analysis (OR 0.81; 95% CI 0.70 to 0.93). One important limitation of this study, and a reason for caution, is the use of multiple comparisons, which can lead to differences at the 0.05 level simply by chance or random variation. Nonetheless, the study suggests that when more than one euploid blastocyst is available, priority might be given to those with a shorter duration of blastulation. Copyright © 2017 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
Adolescents' View of Family Functioning: A Validation of the RES.
ERIC Educational Resources Information Center
Chambliss, Catherine; And Others
The contextual model argues that people in a relationship must experience a sense of loyalty, fairness, and reciprocity in order to build commitment and trust and provide ongoing mutual care. The Relational Ethics Scale (RES), which assess key relational variables, was developed for use in empirical research to test the theoretical framework of…
Education Business Plan 2008-11: Ministry Business Plan
ERIC Educational Resources Information Center
Alberta Education, 2008
2008-01-01
The Ministry of Education has identified one core business that is an ongoing key responsibility. It is called "Core Business One: Lead and Support the Education System So That All Students Are Successful at Learning." The core business includes three goals with specific outcomes that describe the end results the Ministry wants to…
A Review of Parent Education Programs for Parents of Children with Autism Spectrum Disorders
ERIC Educational Resources Information Center
Schultz, Tia R.; Schmidt, Carla T.; Stichter, Janine P.
2011-01-01
Benefits of parent education have been demonstrated for decades. However, there exists a lack of formative evaluation of parent education for parents of children with autism spectrum disorders (ASD), limiting the interpretation of ongoing and future research. To understand the current status, key characteristics, and evaluation methods of parent…
75 FR 1803 - Lower Florida Keys Refuges, Monroe County, FL
Federal Register 2010, 2011, 2012, 2013, 2014
2010-01-13
... fully assessed and the effect of climate change (e.g., sea level rise) is not known. We would protect... (e.g., hurricanes, wildfire) and global climate change, particularly sea level rise. Current ongoing... evaluate the potential impacts of sea level rise on the ecology of wading birds. Since a primary purpose of...
ERIC Educational Resources Information Center
D'Angelo, Anne Marie
2010-01-01
Internationalization is a multi-faceted, multi-dimensional and complex concept described most notably as a higher educational process that integrates an international perspective into its organizational leadership, vision, and curricular goals. Success is dependent upon ongoing engagement of a multitude of internal and external stakeholders with…
Developing Inclusive Schools: A Systemic Approach
ERIC Educational Resources Information Center
Kinsella, William; Senior, Joyce
2008-01-01
This paper emerges from an ongoing study which involved, firstly, key informant interviews with strategic personnel within the Irish education system, such personnel representing both service providers and service users. The first part of this paper provides a brief summary of the findings of that aspect of the study in relation to the key…
Canadian Schools in Transition: Moving from Dual Education Systems to Inclusive Schools.
ERIC Educational Resources Information Center
Lupart, Judy; Webber, Charles
2002-01-01
This article analyzes the many meanings of school restructuring and highlights the ongoing nature of school reform in Canadian schools. Following a selective chronology of general and special education reform, it attempts to capture what appear to be the key features of school reform and progressive inclusion. (Contains references.) (Author/CR)
Identifying and Articulating Library Connections to Student Success
ERIC Educational Resources Information Center
Massengale, Lisa; Piotrowski, Pattie; Savage, Devin
2016-01-01
Engaging in ongoing assessment is key to libraries demonstrating their value to their institutions. This study is an initial step in a STEM library's long-term goal of measuring the library's connection to, and impact on, student academic success markers such as retention and persistence. Initial results showed that any library usage was always…
ERIC Educational Resources Information Center
Maxwell, Aimee; Riley, Philip
2017-01-01
Most research into emotional labour is focussed on front-line service staff and health professionals, in short-term interactions. Little exists exploring the emotional labour involved in repeated on-going interactions by educational leaders with key stakeholders. This study explored the relationships between emotional demands, three emotional…
Marking Extended Essays on Screen: Exploring the Link between Marking Processes and Comprehension
ERIC Educational Resources Information Center
Johnson, Martin; Hopkin, Rebecca; Shiell, Hannah
2012-01-01
Technological developments are impacting upon UK assessment practices in many ways. For qualification awarding bodies, a key example of such impact is the ongoing shift towards examiners marking digitally scanned copies of examination scripts on screen rather than the original paper documents. This digitisation process has obvious benefits,…
Stirling engines for automobiles
NASA Technical Reports Server (NTRS)
Beremand, D. G.
1979-01-01
The results of recent and ongoing automobile Stirling engine development efforts are reviewed and technology status and requirements are identified. Key technology needs include those for low cost, high temperature (1300 - 1500 F) metal alloys for heater heads, and reliable long-life, low-leakage shaft seals. Various fuel economy projections for Stirling powered automobiles are reviewed and assessed.
ERIC Educational Resources Information Center
Woodbridge, Michelle W.; Yu, Jennifer; Goldweber, Asha; Golan, Shari; Stein, BradleyD.
2015-01-01
One key objective of California's Statewide Prevention and Early Intervention (PEI) Student Mental Health (SMH) initiative funded under Proposition 63 was to establish a formal process for ongoing collaboration between higher education systems and county mental health, and to increase collaboration among higher education campuses to improve…
Clones, Drones and Dragons: Ongoing Uncertainties around School Leader Development
ERIC Educational Resources Information Center
Walker, Allan
2015-01-01
This article examines a number of key issues around successful school leadership and leader development. Three metaphors are used to frame, track and analyse recent research and commentary in the area--these are clones, drones and dragons. Although development mechanisms rarely fall neatly within one category, the metaphors provide a useful way to…
A Need for a Framework for Curriculum Evaluation in Oman
ERIC Educational Resources Information Center
Al-Jardani, Khalid Salim; Siraj, Saedah; Abedalaziz, Nabeel
2012-01-01
The field of curriculum evaluation is a key part of the educational process. This means that this area needs to be developed continuously and requires ongoing research. This paper highlights curriculum evaluation in Oman, different evaluation procedures and methods and instruments used. The need for a framework for curriculum evaluation is a vital…
The Bradley Challenge: A Sea Change for Australian Universities?
ERIC Educational Resources Information Center
Putnam, Thomas; Gill, Judith
2011-01-01
This paper begins with a focus on the problematic nature of one key term in the Bradley Report. "Socioeconomic status," or SES as commonly used, lacks clear definition leading to ongoing debates about its measurement. A working consensus on SES and its measurement is necessary for the report's recommendations to proceed effectively. Next…
Inclusion of Indigenous Peoples in CONFINTEA VI and Follow-Up Processes
ERIC Educational Resources Information Center
Morrison, Sandra L.; Vaioleti, Timote M.
2011-01-01
This paper discusses key issues raised by indigenous peoples during CONFINTEA VI and proposes strategies to enable them to participate in ongoing processes. Indigenous peoples are not involved in the design, implementation and monitoring of adult education programmes, and this often results in a "one-size-fits-all" model. This article…
Interview with Hilla Patell on the History of the Observation
ERIC Educational Resources Information Center
O'Shaughnessy, Molly; Patell, Hilla
2016-01-01
In this interview conducted at the NAMTA conference, "Observation: The Key to Unlocking the Child's Potential", Molly O'Shaughnessy discusses the history of observation with Hilla Patell. Patell shares stories of the people who were instrumental in creating a culture of observation as an ongoing discipline to be practiced. She goes on to…
Board Member Development in the Public, Voluntary and Social Housing Sectors
ERIC Educational Resources Information Center
Ward, Carolyn; Preece, David
2012-01-01
Purpose: Given a number of recent and ongoing changes to the role and responsibilities of executive and non-executive board members of UK social housing organisations, the paper aims to offer a literature review which explores the development provision for board members within such organisations. The paper's key question is: "How are…
Final report of the key comparison of APMP.AUV.V-K2
NASA Astrophysics Data System (ADS)
Usuda, Takashi; Ota, Akihiro; Nozato, Hideaki; Ishigami, Tamio; Kokuyama, Wataru; Plangsangmas, Virat; Rattanangkul, Pairoj; Yih Tsuei, Kuang; Huang, Yu-Chung; Chee Keong, Chan; Shan, Cui
2017-01-01
A key comparison of vibration acceleration APMP.AUV.V-K2, which is an upgrade from APMP.AUV.V-K1.1, has been made within the Asia Pacific Metrology Programme (APMP) to include three national laboratories; the CMS-ITRI (Chinese Taipei), the NIMT (Thailand) and the A*Star (Singapore). One pilot laboratory, the NMIJ (Japan), participated to link the RMO APMP results to the CIPM CC key comparison (CCAUV.V-K2), according to the decision of the CCAUV10/D7 during the 10th CCAUV meeting. The admissible acceleration amplitude ranges from 10 m/s2 to 200 m/s2 over the frequency range from 40 Hz to 5 kHz. The RMO APMP results demonstrate the agreement with the key comparison reference value of CCAUV.V-K2 within the expanded uncertainties considering the armature effect of vibration exciter in a high-frequency range. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCAUV, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Avison, Janine; Barham, Richard
2014-01-01
This document and the accompanying spreadsheets constitute the final report for key comparison CCAUV.A-K5 on the pressure calibration of laboratory standard microphones in the frequency range from 2 Hz to 10 kHz. Twelve national measurement institutes took part in the key comparison and the National Physical Laboratory piloted the project. Two laboratory standard microphones IEC type LS1P were circulated to the participants and results in the form of regular calibration certificates were collected throughout the project. One of the microphones was subsequently deemed to have compromised stability for the purpose of deriving a reference value. Consequently the key comparison reference value (KCRV) has been made based on the weighted mean results for sensitivity level and for sensitivity phase from just one of the microphones. Corresponding degrees of equivalence (DoEs) have also been calculated and are presented. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCAUV, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Final report of the key comparison APMP.QM-K9: APMP comparison on pH measurement of phosphate buffer
NASA Astrophysics Data System (ADS)
Hioki, Akiharu; Ohata, Masaki; Cherdchu, Chainarong; Tangpaisarnkul, Nongluck
2011-01-01
The APMP.QM-K9 was organised by TCQM of APMP to test the abilities of the national metrology institutes in the APMP region to measure a pH value of a phosphate buffer. This APMP comparison on pH measurement was proposed by the National Metrology Institute of Japan, NMIJ, and the National Institute of Metrology of Thailand, NIMT, in August 2009. After approval by TCQM, the comparison has been conducted by NMIJ and NIMT. The comparison is a key comparison following CCQM-K9, CCQM-K9.1 and CCQM-K9.2. The comparison material was a phosphate buffer of pH around 6.86 and the measurement temperatures were 15 °C, 25 °C and 37 °C. This is the first APMP key comparison on pH measurement and the third APMP comparison on pH measurement following APMP.QM-P06 (two phosphate buffers) in 2004 and APMP.QM-P09 (a phthalate buffer) in 2006. The results can be used further by any participant to support its CMC claim for a phosphate buffer. That claim will concern the pH method employed by the participant during this comparison and will cover the temperature(s) used or the full temperature range between 15 °C and 37 °C for the participant which measured pH values at the three temperatures. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
GenColors: annotation and comparative genomics of prokaryotes made easy.
Romualdi, Alessandro; Felder, Marius; Rose, Dominic; Gausmann, Ulrike; Schilhabel, Markus; Glöckner, Gernot; Platzer, Matthias; Sühnel, Jürgen
2007-01-01
GenColors (gencolors.fli-leibniz.de) is a new web-based software/database system aimed at an improved and accelerated annotation of prokaryotic genomes considering information on related genomes and making extensive use of genome comparison. It offers a seamless integration of data from ongoing sequencing projects and annotated genomic sequences obtained from GenBank. A variety of export/import filters manages an effective data flow from sequence assembly and manipulation programs (e.g., GAP4) to GenColors and back as well as to standard GenBank file(s). The genome comparison tools include best bidirectional hits, gene conservation, syntenies, and gene core sets. Precomputed UniProt matches allow annotation and analysis in an effective manner. In addition to these analysis options, base-specific quality data (coverage and confidence) can also be handled if available. The GenColors system can be used both for annotation purposes in ongoing genome projects and as an analysis tool for finished genomes. GenColors comes in two types, as dedicated genome browsers and as the Jena Prokaryotic Genome Viewer (JPGV). Dedicated genome browsers contain genomic information on a set of related genomes and offer a large number of options for genome comparison. The system has been efficiently used in the genomic sequencing of Borrelia garinii and is currently applied to various ongoing genome projects on Borrelia, Legionella, Escherichia, and Pseudomonas genomes. One of these dedicated browsers, the Spirochetes Genome Browser (sgb.fli-leibniz.de) with Borrelia, Leptospira, and Treponema genomes, is freely accessible. The others will be released after finalization of the corresponding genome projects. JPGV (jpgv.fli-leibniz.de) offers information on almost all finished bacterial genomes, as compared to the dedicated browsers with reduced genome comparison functionality, however. As of January 2006, this viewer includes 632 genomic elements (e.g., chromosomes and plasmids) of 293 species. The system provides versatile quick and advanced search options for all currently known prokaryotic genomes and generates circular and linear genome plots. Gene information sheets contain basic gene information, database search options, and links to external databases. GenColors is also available on request for local installation.
Results and evaluation of key comparison CCM.P-K12.1 for very low helium flow rates (leak rates)
NASA Astrophysics Data System (ADS)
Šetina, Janez; Vičar, Martin; Pražák, Dominik
2015-01-01
The Czech Metrology Institute (CMI) took part and failed to prove equivalence in the Key Comparison CCM.P-K12 of helium leak artefacts (leak rates) into vacuum. After identifying and eliminating the cause of the failure, the Institute of Metals and Technology (IMT) of Slovenia, a successful participant in CCM.P-K12, volunteered to serve as pilot and link in a following bilateral comparison of IMT and CMI that obtained designation CCM.P-K12.1 in June 2012. It was decided to perform the comparison with a glass permeation helium leak artefact at nominally 3.10-11 mol/s (7.4.10-7 mbar.L.s-1) at 23 °C. Both the laboratory standards took part in CCM.P-K12 and were considered as primary. The comparison measurements were performed in October 2012. CMI proved equivalence both with IMT and with the reference value of the key comparison CCM.P-K12. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Evaluating nuclear physics inputs in core-collapse supernova models
NASA Astrophysics Data System (ADS)
Lentz, E.; Hix, W. R.; Baird, M. L.; Messer, O. E. B.; Mezzacappa, A.
Core-collapse supernova models depend on the details of the nuclear and weak interaction physics inputs just as they depend on the details of the macroscopic physics (transport, hydrodynamics, etc.), numerical methods, and progenitors. We present preliminary results from our ongoing comparison studies of nuclear and weak interaction physics inputs to core collapse supernova models using the spherically-symmetric, general relativistic, neutrino radiation hydrodynamics code Agile-Boltztran. We focus on comparisons of the effects of the nuclear EoS and the effects of improving the opacities, particularly neutrino--nucleon interactions.
ERIC Educational Resources Information Center
Hilton, Annette; Hilton, Geoff; Dole, Shelley; Goos, Merrilyn
2016-01-01
Proportional reasoning, the ability to use ratios in situations involving comparison of quantities, is essential for mathematical competence, especially in the middle school years, and is an important determinant of success beyond school. Research shows students find proportional reasoning and its foundational concepts difficult. Proportional…
Doctor, It Hurts When I Do This
2009-10-01
procedures is 520 pages. For comparison, Moby Dick is a minnow-sized 420 pages and even Tolstoy’s epic War and Peace is dwarfed at 699 pages. As the... advertised to be. The ongoing events in the financial world offer an interest- ing case in point. The global financial system has become highly
Unbiased geocoding of maternal residence is critical to the success of an ongoing case-control study of exposure to five criteria air pollutants and the risk of selected birth defects in seven Texas counties between 1997 and 2000. The geocoded residence at delivery will be used ...
Norms and Goals of Appraisal of German Teachers for Students with Learning Disabilities
ERIC Educational Resources Information Center
Wilbert, Jurgen; Grunke, Matthias
2010-01-01
Although there is an ongoing debate about which achievement feedback is most useful, the majority of researchers agree that social comparisons and a focus on competition are inappropriate for students with learning disabilities and otherwise academically-challenged students. They are highly at-risk to be unfavorably influenced by inappropriate…
ERIC Educational Resources Information Center
Brown, J. David; VanWagoner, Randall J.
This paper reports on an ongoing organizational climate assessment used as one of 10 indicators of institutional effectiveness at a midsize suburban community college. Organizational climate is thought to allow more precise specifications than the overall organizational culture and facilitates, a more comprehensive comparison of change in both…
Now Is the Moment: The State, Public Education, & Communities of Resistance in Oaxaca & Wisconsin
ERIC Educational Resources Information Center
Hones, Donald
2012-01-01
This study draws from narrative research, wherein stories of individuals, groups, and communities are central to the interpretation. Through a process of interpretive interactionism, the author examined the groups and institutions involved in the ongoing conflict between the state and public education in Oaxaca, and then included comparisons and…
ERIC Educational Resources Information Center
Wasik, Barbara A.; Hindman, Annemarie H.
2011-01-01
In a randomized control study, Head Start teachers were assigned to either an intervention group that received intensive, ongoing professional development (PD) or to a comparison group that received the "business as usual" PD provided by Head Start. The PD intervention provided teachers with conceptual knowledge and instructional…
2008-07-01
identification sensor is then VrT where T is some reasonable time in comparison to the approach speed of a potentially hostile contact. In fact, if the...effective range of the identification sensor on the mobile platform is VrT = VrA/Vh = h r V VA Further detail of such analysis is ongoing as part
A practical guide to exercise training for heart failure patients.
Smart, Neil; Fang, Zhi You; Marwick, Thomas H
2003-02-01
Exercise training has been shown to improve exercise capacity in patients with heart failure. We sought to examine the optimal strategy of exercise training for patients with heart failure. Review of the published data on the characteristics of the training program, with comparison of physiologic markers of exercise capacity in heart failure patients and healthy individuals and comparison of the change in these characteristics after an exercise training program. Many factors, including the duration, supervision, and venue of exercise training; the volume of working muscle; the delivery mode (eg, continuous vs. intermittent exercise), training intensity; and the concurrent effects of medical treatments may influence the results of exercise training in heart failure. Starting in an individually prescribed and safely monitored hospital-based program, followed by progression to an ongoing and progressive home program of exercise appears to be the best solution to the barriers of anxiety, adherence, and "ease of access" encountered by the heart failure patient. Various exercise training programs have been shown to improve exercise capacity and symptom status in heart failure, but these improvements may only be preserved with an ongoing maintenance program.
CCM key comparison CCM.D-K4 'Hydrometer'
NASA Astrophysics Data System (ADS)
Lorefice, S.; Becerra, L. O.; Lenard, E.; Lee, Y. J.; Lee, W. G.; Madec, T.; Meury, P. A.; Caceres, J.; Santos, C.; Vamossy, C.; Man, J.; Fen, K.; Toda, K.; Wright, J.; Bettin, H.; Toth, H.
2016-01-01
This report presents the comparison philosophy, methodology, analysis and the results of the designed CCM.D-K4 key comparison that covered the calibration of high resolution hydrometers for liquid and alcoholometers in the density range 600 kg/m3 to 2000 kg/m3 at the temperature of 20°C. The main purpose of this comparison was not only to evaluate the degree of equivalence in the calibration of high accuracy hydrometers between NMI participants, but also to link, were it is possible, the results of previous comparisons to Key Comparison Reference Values (KCRVs) of CCM.D-K4. Eleven NMI laboratories took part in the CCM.D-K4 divided in two groups (petals). With the CCM.D-K4 purpose, two similar sets consisting of three hydrometers for liquid density determinations and an alcoholometer were circulated to the NMI participants as a travelling standard in the time interval from January 2011 to April 2012. Twelve Key Comparison Reference Values (KCRVs) for each petal have been obtained at the density values related to the tested density marks of the transfer standards by the results of participants. The KCRVs and corresponding uncertainties were calculated by the weighted mean in the case of consistent results, otherwise the median was used. The degree of equivalence (DoE) with respect to the corresponding KCRV was determined for each participant and, in this particular comparison, the Weighted Least Squares (WLS) method was used to link the individual DoE of each participant by a continuous function. Significant drift of the transfer standards was not detected. This report also gives instructions on calculating pair-wise degrees of equivalence, with the addition of any information on correlations that may be necessary to estimate more accurately as well as the procedure for linking international comparisons to the CCM.D-K4. Finally an example of linkage to the CCM.D-K4 is given by dealing with the results of the bilateral comparison between INRiM and NMIA, which was added to this comparison so that all participants were engaged after the breakage of the 9340171 artefact. A particularly good agreement was found among the results provided by most of the participants, even if some systematic differences and either underestimated or overestimated uncertainties of the submitted results can be identified with respect to the KCRVs. In general the deviations of the laboratory results to the KCRVs are within of 1/3rd to 1/4th of a scale division and the uncertainty at 95% is usually within half a division. During the analysis of the submitted results, a systematic difference between the first and last immersed mark was also noted, possibly due to a temperature gradient along the stem and/or wetting of the stem around the tested mark, and therefore a corrected claimed uncertainty from each laboratory is expected. However this comparison may help the laboratories to solve some residual or marginal problems as well as to better understand the uncertainty components. The comparison fully supports the calibration measurement capabilities table in the BIPM key comparison database (KCDB). The results can be used to link regional comparisons to this CCM key comparison Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Rummel, Jan; Wesslein, Ann-Katrin; Meiser, Thorsten
2017-05-01
Event-based prospective memory (PM) is the ability to remember to perform an intention in response to an environmental cue. Recent microstructure models postulate four distinguishable stages of successful event-based PM fulfillment. That is, (a) the event must be noticed, (b) the intention must be retrieved, (c) the context must be verified, and (d) the intended action must be coordinated with the demands of any currently ongoing task (e.g., Marsh, Hicks, & Watson, 2002b). Whereas the cognitive processes of Stages 1, 2, and 3 have been studied more or less extensively, little is known about the processes of Stage 4 so far. To fill this gap, the authors manipulated the magnitude of response overlap between the ongoing task and the PM task to isolate Stage-4 processes. Results demonstrate that PM performance improves in the presence versus absence of a response overlap, independent of cue saliency (Experiment 1) and of demands from currently ongoing tasks (Experiment 2). Furthermore, working-memory capacity is associated with PM performance, especially when there is little response overlap (Experiments 2 and 3). Finally, PM performance benefits only from strong response overlap, that is, only when the appropriate ongoing-task and PM response keys were identical (Experiment 4). They conclude that coordinating ongoing-task and PM actions puts cognitive demands on the individual which are distinguishable from the demands imposed by cue-detection and intention-retrieval processes. (PsycINFO Database Record (c) 2017 APA, all rights reserved).
Groenewoud, Eva R; Cantineau, Astrid E P; Kollen, Boudewijn J; Macklon, Nick S; Cohlen, Ben J
2013-01-01
BACKGROUND Frozen-thawed embryo transfer (FET) enables surplus embryos derived from IVF or IVF-ICSI treatment to be stored and transferred at a later date. In recent years the number of FET cycles performed has increased due to transferring fewer embryos per transfer and improved laboratory techniques. Currently, there is little consensus on the most effective method of endometrium preparation prior to FET. METHODS Using both MEDLINE and EMBASE database a systematic review and meta-analysis of literature was performed. Case-series, case-control studies and articles in languages other than English, Dutch or Spanish were excluded. Those studies comparing clinical and ongoing pregnancy rates as well as live birth rates in (i) true natural cycle FET (NC-FET) versus modified NC-FET, (ii) NC-FET versus artificial cycle FET (AC-FET), (iii) AC-FET versus artificial with GnRH agonist cycle FET and (iv) NC-FET versus artificial with GnRH agonist cycle FET were included. Forest plots were constructed and relative risks or odds ratios were calculated. RESULTS A total of 43 publications were selected for critical appraisal and 20 articles were included in the final review. For all comparisons, no differences in the clinical pregnancy rate, ongoing pregnancy rate or live birth rate could be found. Based on information provided in the articles no conclusions could be drawn with regard to cancellation rates. CONCLUSIONS Based on the current literature it is not possible to identify one method of endometrium preparation in FET as being more effective than another. Therefore, all of the current methods of endometrial preparation appear to be equally successful in terms of ongoing pregnancy rate. However, in some comparisons predominantly retrospective studies were included leaving these comparisons subject to selection and publication bias. Also patients' preferences as well as cost-efficiency were not addressed in any of the included studies. Therefore, prospective randomized studies addressing these issues are needed.
ERIC Educational Resources Information Center
Richmond, Gail; Dershimer, R. Charles; Ferreira, Maria; Maylone, Nelson; Kubitskey, Beth; Meriweather, Alycia
2017-01-01
In this paper, we present details of a partnership undertaken by four universities with field-based, alternative STEM teacher preparation programs and a large urban school district to provide ongoing professional support for teachers serving as mentors for individuals preparing for careers in high-poverty schools. We also present key findings…
Education Business Plan 2010-13. Budget 2010: Striking the Right Balance
ERIC Educational Resources Information Center
Alberta Education, 2010
2010-01-01
The ministry has identified one core business that is an ongoing key responsibility. It is called "Core Business One: Lead and Support the Education System So That All Students Are Successful at Learning." The core business includes four goals with specific outcomes that describe the end results the ministry wants to achieve in…
Media Scrutiny of Higher Education: An Ongoing Challenge and Long-Term Trend
ERIC Educational Resources Information Center
Peyronel, Anthony C.
2004-01-01
Increasing skepticism was identified as a key trend in a recent American Journalism Review assessment of media coverage of higher education. However, this trend is hardly new, as American colleges and universities have been subjected to intense media scrutiny for at least the last two decades. This article examines the frequently adversarial…
Towards an Effective Freeware Resource for Music Composition in the Primary Classroom
ERIC Educational Resources Information Center
Hart, Adam
2017-01-01
This paper presents an ongoing project to develop a freeware resource for music composition in the primary classroom. The national curriculum for music at Key Stages 1 and 2 calls for students to "compose music for a range of purposes using the inter-related dimensions of music", a challenging aim that demands significant guidance,…
The Social World, the Creative Self, and the Ongoing Achievement of Freedom
ERIC Educational Resources Information Center
Mayer, Susan Jean
2017-01-01
As an educator, Maxine Greene returned repeatedly to the dynamic transaction that John Dewey had theorized between a vital social world and individual creativity. With Dewey, she viewed mutually transformative relations with others as the wellspring of all personal growth and social progress and as key to achieving a form of freedom that both…
The Perceived and Real Value of Health Information Exchange in Public Health Surveillance
ERIC Educational Resources Information Center
Dixon, Brian Edward
2011-01-01
Public health agencies protect the health and safety of populations. A key function of public health agencies is surveillance or the ongoing, systematic collection, analysis, interpretation, and dissemination of data about health-related events. Recent public health events, such as the H1N1 outbreak, have triggered increased funding for and…
Today's Authoring Tools for Tomorrow's Semantic Web.
ERIC Educational Resources Information Center
Dingley, Andy; Shabajee, Paul
This paper reports on the development of a prototype authoring tool developed as part of on-going research around the needs of the ARKive project. The project holds text, rich-media and descriptions of factual statements about bio-diversity and conservation information. A key user community is that of school age children, requiring the mark-up of…
ERIC Educational Resources Information Center
Piotrowska-Piatek, Agnieszka
2017-01-01
In the context of the ongoing changes in the management systems of higher education, the issue of higher education institutions' (HEIs) relationships with external stakeholders are of key importance. This article discusses this problem from the perspective of Polish higher education system. The aim of it is to answer the following questions: (1)…
ERIC Educational Resources Information Center
Olimpo, Jeffrey T.; Kumi, Bryna C.; Wroblewski, Richard; Dixon, Bonnie L.
2015-01-01
Two-dimensional (2D) diagrams are essential in chemistry for conveying and communicating key knowledge about disciplinary phenomena. While experts are adept at identifying, interpreting, and manipulating these representations, novices often are not. Ongoing research efforts in the field suggest that students' effective use of concrete and virtual…
Studies of Dropouts. Status Report.
ERIC Educational Resources Information Center
Austin Independent School District, TX. Office of Research and Evaluation.
This document provides a brief overview of the ongoing dropout studies cited in the press and around the Austin Independent School District (AISD) in Austin, Texas. It includes a list of key observations which notes that the dropout rate among adolescents is too high; that approximately 20% of 16- to 24-year-olds in Texas do not have a high school…
ERIC Educational Resources Information Center
Custer, Nic
2015-01-01
This paper focuses on how the University of Michigan-Flint's Innovation Incubator supports emerging for-profit businesses and nonprofit organizations through programming, business plan development, and ongoing mentorship. The Incubator is especially interested in supporting start-ups that address key social issues in the surrounding community,…
Teaching Science or Cultivating Values? Conservation NGOs and Environmental Education in Costa Rica
ERIC Educational Resources Information Center
Blum, Nicole
2009-01-01
A key ongoing debate in environmental education practice and its research relates to the content and goals of environmental education programmes. Specifically, there is a long history of debate between advocates of educational perspectives that emphasise the teaching of science concepts and those that seek to more actively link environmental and…
The Self in Action Effects: Selective Attenuation of Self-Generated Sounds
ERIC Educational Resources Information Center
Weiss, Carmen; Herwig, Arvid; Schutz-Bosbach, Simone
2011-01-01
The immediate experience of self-agency, that is, the experience of generating and controlling our actions, is thought to be a key aspect of selfhood. It has been suggested that this experience is intimately linked to internal motor signals associated with the ongoing actions. These signals should lead to an attenuation of the sensory consequences…
Developing Capacity for Research and Teaching in Higher Education: A Case of Makerere University
ERIC Educational Resources Information Center
Mugimu, Christopher B.; Nakabugo, Mary Goretti; Katunguka-Rwakishaya, Eli
2013-01-01
Research and teaching are key pillars in higher education. This article examines the factors associated with the current faculty research and teaching agenda at Makerere University (MU) and explores the realities of ongoing capacity building for faculty in research and teaching. This research was guided by the following questions: What motivates…
When Is 100% Not 100%? The Use of Safe Harbor to Make Adequate Yearly Progress
ERIC Educational Resources Information Center
Polikoff, Morgan S.; Wrabel, Stephani L.
2013-01-01
Debate over the design of state and federal accountability systems is an important ongoing issue for policy makers. As we move toward next-generation accountability through No Child Left Behind's (NCLB) waivers and reauthorization drafts, it is important to understand the implementation and effects of key elements of prior accountability systems.…
Social Learning as a Key Factor in Sustainability Transitions: The Case of Okayama City
ERIC Educational Resources Information Center
Didham, Robert J.; Ofei-Manu, Paul; Nagareo, Masaaki
2017-01-01
The Okayama Education for Sustainable Development (ESD) Project is an ongoing initiative in Okayama City, Japan, established in 2005 by the Regional Centre of Expertise (RCE) Okayama and the Okayama Municipal Government with the aim "to create a community where people learn, think and act together towards realising a sustainable…
Physics Myth Busting: A Lab-Centered Course for Non-Science Students
ERIC Educational Resources Information Center
Madsen, Martin John
2011-01-01
There is ongoing interest in how and what we teach in physics courses for non-science students, so-called "physics for poets" courses. Art Hobson has effectively argued that teaching science literacy should be a key ingredient in these courses. Hobson uses Jon Millers definition of science literacy, which has two components: first, "a basic…
ERIC Educational Resources Information Center
Scotland, Miriam
2006-01-01
The relevancy of program curricula in tourism and hospitality education has been called into question by key stakeholders in light of ongoing changes in the multifaceted tourism and hospitality industry. Various program models have been identified. Program content and quality of student preparedness have been debated. Balance and areas of emphasis…
Bridging the Distance: The Use of Blogs as Reflective Learning Tools for Placement Students
ERIC Educational Resources Information Center
Wolf, Katharina
2010-01-01
This paper reviews the effectiveness of web logs ("blogs"), or online journals, within the context of a compulsory final-year placement unit for public relations students. The key goal behind the use of Web2.0 technology was to encourage ongoing, reflective practice via an exchange between students thereby limiting feelings of isolation…
KEY COMPARISON: Final report of the CCQM-K56: Ca, Fe, Zn and Cu in whole fat soybean powder
NASA Astrophysics Data System (ADS)
Liandi, Ma; Qian, Wang
2010-01-01
The CCQM-K56 key comparison was organized by the Inorganic Analysis Working Group (IAWG) of CCQM as a follow-up to completed pilot study CCQM-P64 to test the abilities of national metrology institutes to measure the amount content of nutritious elements in whole fat soybean powder. A pilot study CCQM-P64.1 was conducted in parallel with this key comparison. The National Institute of Metrology (NIM), P. R. China, acted as the coordinating laboratory. Eleven NIMs participated in CCQM-K56. Four elements - Ca, Fe, Zn and Cu - in different concentration levels have been studied. Different measurement methods (IDMS, ICP-MS, ICP-OES, AAS and INAA) and the microwave digestion method were used. The agreement of the results of CCQM-K56 is very good, and obviously better than that of the original P64. It shows that the capability of all of the participants had been promoted from the original pilot study to this key comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
Effects of aberrant gamma frequency oscillations on prepulse inhibition.
Jones, Nigel C; Anderson, Paul; Rind, Gil; Sullivan, Caley; van den Buuse, Maarten; O'Brien, Terence J
2014-10-01
Emerging literature implicates abnormalities in gamma frequency oscillations in the pathophysiology of schizophrenia, with hypofunction of N-methyl-D-aspartate (NMDA) receptors implicated as a key factor. Prepulse inhibition (PPI) is a behavioural measure of sensorimotor gating, which is disrupted in schizophrenia. We studied relationships between ongoing and sensory-evoked gamma oscillations and PPI using pharmacological interventions designed to increase gamma oscillations (ketamine, MK-801); reduce gamma oscillations (LY379268); or disrupt PPI (amphetamine). We predicted that elevating ongoing gamma power would lead to increased 'neural noise' in cortical circuits, dampened sensory-evoked gamma responses and disrupted behaviour. Wistar rats were implanted with EEG recording electrodes. They received ketamine (5 mg/kg), MK-801 (0.16 mg/kg), amphetamine (0.5 mg/kg), LY379268 (3 mg/kg) or vehicle and underwent PPI sessions with concurrent EEG recording. Ketamine and MK-801 increased the power of ongoing gamma oscillations and caused time-matched disruptions of PPI, while amphetamine marginally affected ongoing gamma power. In contrast, LY379268 reduced ongoing gamma power, but had no effect on PPI. The sensory gamma response evoked by the prepulse was reduced following treatment with all psychotomimetics, associating with disruptions in PPI. This was most noticeable following treatment with NMDA receptor antagonists. We found that ketamine and MK-801 increase ongoing gamma power and reduce evoked gamma power, both of which are related to disruptions in sensorimotor gating. This appears to be due to antagonism of NMDA receptors, since amphetamine and LY379268 differentially impacted these outcomes and possess different neuropharmacological substrates. Aberrant gamma frequency oscillations caused by NMDA receptor hypofunction may mediate the sensory processing deficits observed in schizophrenia.
Managing the pursuit of health and wealth: the key challenges.
Fidler, David P; Drager, Nick; Lee, Kelley
2009-01-24
This article forms part of a six-part Series on trade and health, and sets the stage for this Series by analysing key aspects of the relationship between trade and health. The Series takes stock of this relation and provides timely analysis of the key challenges facing efforts to achieve an appropriate balance between trade and health across a diverse range of issues. This introductory article reviews how trade and health have risen and expanded on global policy agendas in the past decade in unprecedented ways, describes how trade and health issues are respectively governed in international relations, examines the ongoing search for policy coherence between the two policy spheres, and highlights the topics of the remaining articles in the Series.
Managing the pursuit of health and wealth: the key challenges
Fidler, David P; Drager, Nick; Lee, Kelley
2009-01-01
This article forms part of a six-part Series on trade and health, and sets the stage for this Series by analysing key aspects of the relationship between trade and health. The Series takes stock of this relation and provides timely analysis of the key challenges facing efforts to achieve an appropriate balance between trade and health across a diverse range of issues. This introductory article reviews how trade and health have risen and expanded on global policy agendas in the past decade in unprecedented ways, describes how trade and health issues are respectively governed in international relations, examines the ongoing search for policy coherence between the two policy spheres, and highlights the topics of the remaining articles in the Series. PMID:19167061
Muraraneza, Claudine; Mtshali, Ntombifikile Gloria; Mukamana, Donatilla
2017-03-01
Although in recent decades reforms to undergraduate nursing and midwifery education have increasingly been guided by the concept of competency-based curriculum in a drive to produce competent graduates in the African context, the topic remains poorly researched in-depth. The related issues and challenges need to be explored in the interest of evidence-based practice. This article stems from a systematic review of qualitative literature on the design and implementation of competency-based curriculum. Data was inductively analyzed using constant comparison. The two categories that emerged were: (i) the need for a paradigm shift to competency-based curriculum; and (ii) the associated issues and challenges, such as a shift from informative to transformative learning, lack or limited of involvement of key stakeholders in curriculum development, focus on hospital-oriented education, lack of preparation of educators, and inappropriate resources. While ongoing reform of nursing and midwifery education continues, much still needs to be done - in particular, extensive financial investment to increase the capacity of educators, mentors and infrastructure, and the development of collaborative frameworks between nursing and midwifery and higher educational councils. © 2016 John Wiley & Sons Australia, Ltd.
A study of ayahuasca use in North America.
Harris, Rachel; Gurel, Lee
2012-01-01
Eighty-one subjects who used ayahuasca at least once in North America answered a lengthy set of open-ended questions and completed the 81-item After the Spiritual Experience Questionnaire. An additional 50 ayahuasca users were interviewed in person. The data for this study represent ayahuasca experience based on more than 2,267 ceremonies. A comparison group of 46 people attending a Catholic spiritual retreat weekend also completed the After the Spiritual Experience Questionnaire. A factor analysis of this questionnaire yielded three factors: Joy in Life, Relationship to the Sacred and Toxic Feelings. Although the ayahuasca users had significantly higher scores on the first two factors, the two groups had modest mean differences indicating a similar response to two very different spiritual experiences. This key finding strongly supports the view that ayahuasca users are engaged in an authentic process as spiritual in nature as that of the retreatants. The qualitative data revealed that ayahuasca users reduced their alcohol intake, ate healthier diets, enjoyed improved mood and greater self-acceptance and felt more loving and compassionate in their relationships. Seventy-four percent of the ayahuasca users said they had a relationship with and received ongoing guidance and support from the spirit of ayahuasca.
Prunuske, Amy; Wilson, Janelle; Walls, Melissa; Marrin, Hannah; Clarke, Benjamin
2016-01-01
With the primary objective of attracting and retaining students from underrepresented backgrounds in the sciences, evaluation of one institution’s program has been ongoing over the past three years. Interviews with mentors in the program followed by focus groups conducted with mentees reveal key factors that shape undergraduate students’ research experiences. In the present study, attention is given to data gathered from 15 mentees in the program, the majority of whom have enrolled in community colleges, represent low socioeconomic backgrounds, and are nontraditional students. The results from focus groups with the mentees provide information on the benefits of participating in the program, characteristics of good mentors, challenges to the mentoring relationship, and the effects of underrepresented status on pursuit of advanced degrees. Comparisons of mentees’ comments about the mentoring relationship with mentors’ comments reveal similar themes and patterns while also demonstrating interesting differences. The qualitative findings are also juxtaposed with participants’ responses on the Survey of Undergraduate Research Experiences. Taken together, the data enhance our understanding of the experiences of underrepresented students in faculty-mentored research programs and highlight challenges and perspectives of students who are transferring to the university from a community college. PMID:27521233
Design principles and field performance of a solar spectral irradiance meter
DOE Office of Scientific and Technical Information (OSTI.GOV)
Tatsiankou, V.; Hinzer, K.; Haysom, J.
2016-08-01
A solar spectral irradiance meter (SSIM), designed for measuring the direct normal irradiance (DNI) in six wavelength bands, has been combined with models to determine key atmospheric transmittances and the resulting spectral irradiance distribution of DNI under all sky conditions. The design principles of the SSIM, implementation of a parameterized transmittance model, and field performance comparisons of modeled solar spectra with reference radiometer measurements are presented. Two SSIMs were tested and calibrated at the National Renewable Energy Laboratory (NREL) against four spectroradiometers and an absolute cavity radiometer. The SSIMs' DNI was on average within 1% of the DNI values reportedmore » by one of NREL's primary absolute cavity radiometers. An additional SSIM was installed at the SUNLAB Outdoor Test Facility in September 2014, with ongoing collection of environmental and spectral data. The SSIM's performance in Ottawa was compared against a commercial pyrheliometer and a spectroradiometer over an eight month study. The difference in integrated daily spectral irradiance between the SSIM and the ASD spectroradiometer was found to be less than 1%. The cumulative energy density collected by the SSIM over this duration agreed with that measured by an Eppley model NIP pyrheliometer to within 0.5%. No degradation was observed.« less
Flavonoids from Piper delineatum modulate quorum-sensing-regulated phenotypes in Vibrio harveyi.
Martín-Rodríguez, Alberto J; Ticona, Juan C; Jiménez, Ignacio A; Flores, Ninoska; Fernández, José J; Bazzocchi, Isabel L
2015-09-01
Quorum sensing (QS), or bacterial cell-to-cell communication, is a key process for bacterial colonization of substrata through biofilm formation, infections, and production of virulence factors. In an ongoing investigation of bioactive secondary metabolites from Piper species, four new flavonoids (1-4), along with five known ones (5-9) were isolated from the leaves of Piper delineatum. Their stereostructures were established by spectroscopic and spectrometric methods, including 1D and 2D NMR experiments, and comparison with data reported in the literature. The compounds were screened for their ability to interfere with QS signaling in the bacterial model Vibrio harveyi. Four compounds from this series (2, 3, 6, and 7) exhibited remarkable activity in the micromolar range, being compounds 3 and 7 particularly attractive since they did not affect bacterial growth. The results suggest that these flavonoids disrupt QS-mediated bioluminescence by interaction with elements downstream LuxO in the QS circuit of V. harveyi, and also, they exhibited a strong dose-dependent inhibition of biofilm formation. The present findings shed light on the QS inhibition mechanisms of flavonoids, underlining their potential applications. Copyright © 2015 Elsevier Ltd. All rights reserved.
Pine, Michael; Sonneborn, Mark; Schindler, Joe; Stanek, Michael; Maeda, Jared Lane; Hanlon, Carrie
2012-01-01
The imperative to achieve quality improvement and cost-containment goals is driving healthcare organizations to make better use of existing health information. One strategy, the construction of hybrid data sets combining clinical and administrative data, has strong potential to improve the cost-effectiveness of hospital quality reporting processes, improve the accuracy of quality measures and rankings, and strengthen data systems. Through a two-year contract with the Agency for Healthcare Research and Quality, the Minnesota Hospital Association launched a pilot project in 2007 to link hospital clinical information to administrative data. Despite some initial challenges, this project was successful. Results showed that the use of hybrid data allowed for more accurate comparisons of risk-adjusted mortality and risk-adjusted complications across Minnesota hospitals. These increases in accuracy represent an important step toward targeting quality improvement efforts in Minnesota and provide important lessons that are being leveraged through ongoing projects to construct additional enhanced data sets. We explore the implementation challenges experienced during the Minnesota Pilot Project and their implications for hospitals pursuing similar data-enhancement projects. We also highlight the key lessons learned from the pilot project's success.
Projected refined product balances in key Latin American countries: A preliminary examination
DOE Office of Scientific and Technical Information (OSTI.GOV)
NONE
1996-06-01
Over the years, the East-West Center (EWC) has developed considerable expertise in refinery modeling, especially in the area of forecasting product balances for countries, given planned capacity changes, changes in product demand, changes in crude slates, and changes in product specifications. This expertise has been applied on an ongoing basis to the major refiners in the Middle East and the Asia-Pacific region, along with the US West Coast as region in its own right. Refinery modeling in these three areas has been ongoing for nearly 15 years at the Center, and the tools and information sources are now well developed.more » To date, the EWC has not applied these tools to Latin America. Although research on Latin America has been an ongoing area of concern at the Center in recent years, the information gathered to date is still not of the level of detail nor quality available for other areas. The modeling efforts undertaken in this report are of a ``baseline`` nature, designed to outline the major issues, attempt a first cut at emerging product balances, and, above all, to elicit commentary from those directly involved in the oil industry in the key countries modeled. Our experience in other regions has shown that it takes a few years dialogue with refiners and government planner in individual countries to develop a reliable database, as well as the insights into operational constraints and practices that make accurate modeling possible. This report is no more than a first step down the road.« less
NASA Astrophysics Data System (ADS)
Budovsky, Ilya
2010-01-01
The APMP international comparison of ac-dc transfer standards at the lowest attainable level of uncertainty, APMP.EM-K6a, started in 2000 and concluded in 2003. This comparison has offered the same range and frequencies as the key comparison CCEM-K6a with the view of providing the National Metrology Institutes (NMIs) of the APMP member economies with an opportunity to link the values of their standards for ac-dc transfer difference to the international reference values. The ac-dc difference of the travelling standard was measured with 3 V applied at standard frequencies of 1 kHz, 20 kHz, 100 kHz and 1 MHz, and optional frequencies of 50 kHz and 500 kHz. The travelling standard has not been damaged and has shown excellent stability. The results submitted by the overwhelming majority of the participants lie well within the reported uncertainty. At the standard frequencies the results have been linked to those of the CCEM-K6a key comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Yoshida, H.; Arai, K.; Akimichi, H.; Hong, S. S.; Song, H. W.
2011-01-01
The results of a key comparison of ultra-high vacuum standards at two national metrology institutes (NMIJ/AIST and KRISS) are reported. This bilateral comparison was carried out from May 2010 to October 2010 within the framework of the Asia-Pacific Metrology Programme (APMP) to determine their degrees of equivalence at pressures in the range from 3 × 10-6 Pa to 9 × 10-4 Pa. The pilot institute was NMIJ/AIST. Two spinning rotor gauges and two hot cathode ionization gauges were used as the transfer standards. NMIJ/AIST used two calibration systems: the dynamic expansion system (NMIJ-DES) and two-stage flow-dividing system (NMIJ-TFS). KRISS used the dynamic expansion system. The transfer standards were sufficiently stable to meet the requirements of the comparison compared with those of previous international comparisons owing to some improvements of the protocol and the transfer standards. The ultra-high vacuum standards of NMIJ/AIST and KRISS were found to be equivalent within their claimed uncertainties in the range from 3 × 10-6 Pa to 9 × 10-5 Pa. The NMIJ-DES results, which have smaller uncertainty than NMIJ-TFS, were transferred to the corresponding CCM key comparison, CCM.P-K3, in the range from 3 × 10-6 Pa to 9 × 10-5 Pa and it is shown that the NMIJ values were equivalent to the CCM key comparison reference value within the claimed uncertainties. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
Zweifel, Martin; Mueller, Christoph; Schaffner, Thomas; Dahinden, Clemens; Matozan, Katja; Driscoll, Robert; Mohacsi, Paul
2009-10-01
Eotaxin/CCL11 chemokine is expressed in different organs, including the heart, but its precise cellular origin in the heart is unknown. Eotaxin is associated with Th2-like responses and exerts its chemotactic effect through the chemokine receptor-3 (CCR3), which is also expressed on mast cells (MC). The aim of our study was to find the cellular origin of eotaxin in the heart, and to assess whether expression is changing during ongoing acute heart transplant rejection, indicating a correlation with mast cell infiltration which we observed in a previous study. In a model of ongoing acute heart transplant rejection in the rat, we found eotaxin mRNA expression within infiltrating macrophages, but not in mast cells, by in situ-hybridization. A five-fold increase in eotaxin protein in rat heart transplants during ongoing acute rejection was measured on day 28 after transplantation, compared to native and isogeneic control hearts. Eotaxin concentrations in donor hearts on day 28 after transplantation were significantly higher compared to recipient hearts, corroborating an origin of eotaxin from cells within the heart, and not from the blood. The quantitative comparison of eotaxin mRNA expression between native hearts, isografts, and allografts, respectively, revealed no statistically significant difference after transplantation, probably due to an overall increase in the housekeeping gene's 18S rRNA during rejection. Quantitative RT-PCR showed an increase in mRNA expression of CCR3, the receptor for eotaxin, during ongoing acute rejection of rat heart allografts. Although a correlation between increasing eotaxin expression by macrophages and mast cell infiltration is suggestive, functional studies will elucidate the role of eotaxin in the process of ongoing acute heart transplant rejection.
Bilateral key comparison on luminous flux COOMET.PR-K4.1. final report
NASA Astrophysics Data System (ADS)
Huriev, M.; Khlevnoy, B.; Tolstykh, G.; Ivashin, E.; Gorchkova, T.
2017-01-01
This report describes an international bilateral key comparison on luminous flux of tungsten lamps between the National Scientific Centre 'Institute of Metrology' (NSC 'IM', Ukraine) and All-Russian Research Institute for Optical and Physical Measurements (VNIIOFI, Russia). The comparison is intended to determine the Degrees of Equivalence (DoE) for NSC 'IM' and the associated expanded uncertainty. VNIIOFI acts as a laboratory, providing the link to the comparison CCPR-K4. The comparison used a set of tungsten incandescent lamps as a transfer standard with a luminous flux of approximately 3800 lm. The determined DoE of NSC 'IM' is -0.94% with an expanded uncertainty (k = 2) of 1.05%. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCPR, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Mielck, Finn; Hass, H. Christian; Holler, Peter; Bartholomä, Alexander; Neumann, Andreas; Kröncke, Ingrid; Reimers, Hans-Christian; Capperucci, Ruggero
2016-04-01
The joint research project WIMO (Wissenschaftliche Monitoringkonzepte für die Deutsche Bucht/Scientific Monitoring Concepts for the German Bight, NE North Sea) aims at providing methods for detection and analysis of seabed habitats using modern remote sensing techniques. Our subproject focuses on hydroacoustic techniques in order to gain information about seafloor environments and sediment dynamics. In a timeframe of four years, several key areas in the German Bight were repeatedly observed using different hydroacoustic gear (i. e. sidescan sonars, single/multibeam echo sounders and sub-bottom profilers). In order to ground-truth the acoustic data, hundreds of grab samples and underwater videos were taken. With these techniques it is possible to distinguish between different seafloor habitats, which range from muddy to sandy seafloors (esp. near the barrier islands) to rugged or vegetated/populated reefs around Helgoland. The conducted monitoring program revealed seasonal changes regarding the abundance of the sand mason worm (Lanice conchilega) and the brittle star (Amphiora filiformis) as well as ongoing sedimentary processes driven by tidal currents and wind/storms. It was also possible to determine relationships between sediment characteristics and benthos in some key areas. An essential part of our project included a comparison between the datasets obtained with different hydroacoustic devices, configurations, and evaluation methods in the same study areas. The investigation reveals that there could be distinct differences in interpreting the data and hence in the determination of prevailing seafloor habitats, especially in very heterogeneous areas and at transition zones between the habitats. Therefore, it is recommended to employ more than one hydroacoustic system (preferably a singlebeam device combined with a wide-swath sonar system) synchronously during a survey in order to gain more reliable and detailed information about the seafloor environments. The results of this project study form an important contribution to ongoing and future projects, in particular with regard to the technical configuration of the sonar systems, the workflows concerning post-processing and validation of the hydroacoustic data as well as the monitoring concepts that were worked out. However, a full automation of these workflows is not feasible. For the time being, measurements, post-processing and data evaluation still need supervision and expert knowledge.
Regional comparison of absolute gravimeters SIM.M.G-K1 key comparison
NASA Astrophysics Data System (ADS)
Newell, D. B.; van Westrum, D.; Francis, O.; Kanney, J.; Liard, J.; Ramirez, A. E.; Lucero, B.; Ellis, B.; Greco, F.; Pistorio, A.; Reudink, R.; Iacovone, D.; Baccaro, F.; Silliker, J.; Wheeler, R. D.; Falk, R.; Ruelke, A.
2017-01-01
Twelve absolute gravimeters were compared during the regional Key Comparison SIM.M.G-K1 of absolute gravimeters. The four gravimeters were from different NMIs and DIs. The comparison was linked to the CCM.G-K2 through EURAMET.M.G-K2 via the DI gravimeter FG5X-216. Overall, the results and uncertainties indicate an excellent agreement among the gravimeters, with a standard deviation of the gravimeters' DoEs better than 1.3 μGal. In the case of the official solution, all the gravimeters are in equivalence well within the declared uncertainties. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Kessler, C.; Burns, D. T.; Alvarez Romero, J. T.; De la Cruz Hernández, D.; Cabrera Vertti, M. R.; Tovar-Muñoz, V. M.
2015-01-01
A direct comparison of the standards for air kerma of the Instituto Nacional de Investigaciones Nucleares (ININ), Mexico, and of the Bureau International des Poids et Mesures (BIPM) was carried out in the 137Cs radiation beam of the BIPM in February 2015. The comparison result, evaluated as a ratio of the ININ and the BIPM standards for air kerma, is 1.0048 with a combined standard uncertainty of 2.0 × 10-3. The results are analysed and presented in terms of degrees of equivalence for entry in the BIPM key comparison database. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Hioki, Akiharu; Asakai, Toshiaki; Maksimov, Igor; Suzuki, Toshihiro; Miura, Tsutomu; Ketrin, Rosi; Nuryatini; Thanh, Ngo Huy; Truong Chinh, Nguyen; Vospelova, Alena; Bastkowski, Frank; Sander, Beatrice; Matzke, Jessica; Prokunin, Sergey; Frolov, Dmitry; Aprelev, Alexey; Dobrovolskiy, Vladimir; Uysal, Emrah; Liv, Lokman; Velina Lara-Manzano, Judith; Montero-Ruiz, Jazmin; Ortiz-Aparicio, JosÉ Luis; Ticona Canaza, Galia; Anuar Mohd Amin, Khirul; Abd Kadir, Haslina; Bakovets, Nickolay; Wong, Siu-Kay; Lam, Wai-Hing
2017-01-01
The APMP.QM-K91 was organised by TCQM of APMP to test the abilities of the national metrology institutes in the APMP region to measure a pH value of a phthalate buffer. This APMP comparison on pH measurement was proposed by the National Metrology Institute of Japan at the APMP-TCQM meeting held September 22-23, 2014. After approval by TCQM, the comparison has been conducted by NMIJ. The comparison is a key comparison following CCQM-K91. The comparison material was a phthalate buffer of pH around 4.0 and the measurement temperatures were 15 °C, 25 °C and 37 °C. This is the third APMP key comparison on pH measurement and the fifth APMP comparison on pH measurement following APMP.QM-P06 (two phosphate buffers) in 2004, APMP.QM-P09 (a phthalate buffer) in 2006, APMP.QM-K9/APMP.QM-P16 (a phosphate buffer) in 2010-2011 and APMP.QM-K19/APMP.QM-P25 (a borate buffer) in 2013-2014. The results can be used further by any participant to support its CMC claim at least for a phthalate buffer. That claim will concern the pH method employed by the participant during this comparison and will cover the used temperature(s) or the full temperature range between 15°C and 37 °C for the participant which measured pH values at the three temperatures. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Lorefice, S.; Becerra, L. O.
2017-01-01
Evaluation of different types of comparisons to a common set of reference values of a CIPM key comparison is essential to satisfy the concept of the CIPM Mutual Recognition Arrangement (CIPM MRA), where the DoEs of any participant who took part in comparisons should be within the Calibration and Measurement Capability (CMC) section of the CIPM MRA Key Comparison Data Base. The subject of this supplementary report is therefore to present the equivalence of each National Metrological Institute (NMI) participant in the CCM.D-K4 'Hydrometer' key comparison, which was performed in the density range 600 kg/m3 to 2000 kg/m3 at the temperature of 20 °C, and the linkage of the European and Inter-American NMI results performed in the RMO.M.D-K4 comparisons as well as those of the supplementary SIM.M.D-S2 to the common set of KCRVs of the CCM.D-K4 'Hydrometer'. The linking procedure has been obtained by numerical simulation, based on the Monte Carlo method, in which the differences in the results of the different comparison between the intended laboratory and one or more linking laboratory/ies, which took part in both comparisons, are correlated with a continuous function describing the DoEs of the linking laboratory/ies with respect to the common set of KCRVs of the CCM.D-K4. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Report of the key comparison APMP.QM-K19. APMP comparison on pH measurement of borate buffer
NASA Astrophysics Data System (ADS)
Hioki, Akiharu; Asakai, Toshiaki; Maksimov, Igor; Suzuki, Toshihiro; Miura, Tsutomu; Obromsook, Krairerk; Tangpaisarnkul, Nongluck; Rodruangthum, Patumporn; Wong, Siu-Kay; Lam, Wai-Hing; Zakaria, Osman; Anuar Mohd. Amin, Khirul; Thanh, Ngo Huy; Máriássy, Michal; Vyskocil, Leos; Hankova, Zuzana; Fisicaro, Paola; Stoica, Daniela; Singh, Nahar; Soni, Daya; Ticona Canaza, Galia; Kutovoy, Viatcheslav; Barbieri Gonzaga, Fabiano; Dias, Júlio Cesar; Vospelova, Alena; Bakovets, Nickolay; Zhanasbayeva, Bibinur
2015-01-01
The APMP.QM-K19 was organised by TCQM of APMP to test the abilities of the national metrology institutes in the APMP region to measure a pH value of a borate buffer. This APMP comparison on pH measurement was proposed by the National Metrology Institute of Japan (NMIJ) and the National Institute of Metrology (Thailand) (NIMT) at the APMP-TCQM meeting held 26-27 November 2012. After approval by TCQM, the comparison has been conducted by NMIJ and NIMT. The comparison is a key comparison following CCQM-K19 and CCQM-K19.1. The comparison material was a borate buffer of pH around 9.2 and the measurement temperatures were 15 °C, 25 °C and 37 °C. This is the second APMP key comparison on pH measurement and the fourth APMP comparison on pH measurement following APMP.QM-P06 (two phosphate buffers) in 2004, APMP.QM-P09 (a phthalate buffer) in 2006 and APMP.QM-K9/APMP.QM-P16 (a phosphate buffer) in 2010-2011. The results can be used further by any participant to support its CMC claim at least for a borate buffer. That claim will concern the pH method employed by the participant during this comparison and will cover the used temperature(s) or the full temperature range between 15°C and 37 °C for the participant which measured pH values at the three temperatures. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
The Comprehension of Rapid Speech by the Blind: Part III. Final Report.
ERIC Educational Resources Information Center
Foulke, Emerson
Accounts of completed and ongoing research conducted from 1964 to 1968 are presented on the subject of accelerated speech as a substitute for the written word. Included are a review of the research on intelligibility and comprehension of accelerated speech, some methods for controlling the word rate of recorded speech, and a comparison of…
ERIC Educational Resources Information Center
Clark, Douglas B.; D'Angelo, Cynthia M.; Schleigh, Sharon P.
2011-01-01
This study investigates the ongoing debate in the conceptual change literature between unitary and elemental perspectives on students' knowledge structure coherence. More specifically, the current study explores two potential explanations for the conflicting results reported by Ioannides and Vosniadou (2002)and diSessa, Gillespie, and Esterly…
Sari C. Saunders; Jiquan Chen; Thomas D. Drummer; Eric J. Gustafson; Kimberley D. Brosofske
2005-01-01
Identifying scales of pattern in ecological systems and coupling patterns to processes that create them are ongoing challenges. We examined the utility of three techniques (lacunarity, spectral, and wavelet analysis) for detecting scales of pattern of ecological data. We compared the information obtained using these methods for four datasets, including: surface...
Matched Comparison of PRAMS and the First Steps Database.
ERIC Educational Resources Information Center
Schubert, Stacey; Cawthon, Laurie
This study compared some of the survey data collected by the Pregnancy Risk Assessment Monitoring System (PRAMS) to information from vital records and administrative records in the First Steps Database (FSDB) for a group of women who gave birth in 1993. PRAMS is an ongoing survey of Washington women who have given birth. The FSDB contains birth…
Some Syndromes Among Suicidal People: The Problem of Suicide Potentiality.
ERIC Educational Resources Information Center
Wold, Carl I.
An on-going research project at the Los Angeles Suicide Prevention Center is attempting to describe the potential suicide. Comparisons on a rating scale were made among patients who commit suicide and a random sample of case histories from the coroner's office. Approximately 10 syndromes or subgroupings of people who commit suicide have been…
Learning by Dispossession: Democracy Promotion and Civic Engagement in Iraq and the United States
ERIC Educational Resources Information Center
Mojab, Shahrzad; Carpenter, Sara
2011-01-01
This paper brings together two ongoing research projects on current citizenship learning programs in Iraq and the United States, both of which draw from the theoretical ground of Marxist-feminist perspective. A particular strength of this paper is its comparison between two American citizenship education programs in the context of neoliberalism,…
The ToxCast program has generated a great wealth of in vitro high throughput screening (HTS) data on a large number of compounds, providing a unique resource of information on the bioactivity of these compounds. However, analysis of these data are ongoing, and interpretation and ...
Enhancing Large-Class Teaching: A Systematic Comparison of Rich-Media Materials
ERIC Educational Resources Information Center
Saunders, F. C.; Hutt, I.
2015-01-01
Large cohorts (>200 students) are an ever-increasing presence in the UK higher education (HE) sector. Providing excellent teaching and learning to these large classes is an ongoing challenge for teaching faculty, a challenge intensified when the cohort comprises 85% non-native English speakers. This paper presents the findings of a project to…
USDA-ARS?s Scientific Manuscript database
The USDA Southeast Watershed Research Laboratory is located in Tifton, Ga, and performs ongoing watershed research for the Tift County area, as well as surrounding counties. Current watershed delineations are based on 1972-1977, 7.5-minute USGS Quadrangle sheets, and require updating. Light Detectio...
Propane in nitrogen, 1000 μmol/mol
NASA Astrophysics Data System (ADS)
Konopelko, L. A.; Kustikov, Y. A.; Kolobova, A. V.; Pankratov, V. V.; Pankov, A. A.; Efremova, O. V.; Rozhnov, M. S.; Melnyk, D. M.; Petryshyn, P. V.; Levbarg, O. S.; Kisel, S. P.; Shpilnyi, S. A.; Yakubov, S. Ye; Bakovec, N. V.; Mironchik, A. M.; Aleksandrov, V. V.
2017-01-01
This article presents the report on the COOMET key comparison COOMET.QM-K111, which is linking to the appropriate CCQM comparison—CCQM-K111 'Propane in nitrogen 1000 μmol/mol'. CCQM-K111 was carried out in 2014-2016 and it was one of a series of key comparisons in the gas analysis area assessing core competences. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Linking results of key and supplementary comparisons of AC/DC voltage transfer references
NASA Astrophysics Data System (ADS)
Velychko, Oleh
2018-04-01
A regional key comparison (KC) COOMET.EM-K6.a and a supplementary comparison (SC) COOMET.EM-S1 of AC/DC voltage transfer references were conducted between participating laboratories from the Eurasian region. Measurements were made over the period 2004-2014. The results showed good agreement between all but one of the participating laboratories. The proposed procedure of linking results of key and SCs of regional metrology organization of AC/DC voltage transfer references is presented. Linking results is realized for COOMET.EM-K6.a and CCEM-K6.a KCs, and for COOMET.EM-K6.a KC and COOMET.EM-S1 SC.
Detecting event-based prospective memory cues occurring within and outside the focus of attention.
Hicks, Jason L; Cook, Gabriel I; Marsh, Richard L
2005-01-01
Event-based prospective memory cues are environmental stimuli that are associated with a previously established intention to perform an activity. Such cues traditionally have been placed in materials that receive focal attention during an ongoing activity. This article reports a direct comparison of event-based cues that occurred either within the focus of attention or at the periphery of such attention. When the cue occurred outside focal attention, manipulating that cue changed event-based prospective memory. The identical manipulation had no effect on event-based responding if the cue occurred within focal attention. These results suggest that cue characteristics can compensate for attention being directed away from an aspect of an ongoing task that contains event-based prospective memory.
NASA Astrophysics Data System (ADS)
Liedberg, Hans
2012-01-01
The Comité Consulatif de Thermométrie (CCT) has organized several key comparisons to compare realizations of the ITS-90 in different National Metrology Institutes. To keep the organization, time scale and data processing of such a comparison manageable, the number of participants in a CCT key comparison (CCT KC) is limited to a few laboratories in each major economic region. Subsequent regional key comparisons are linked to the applicable CCT KC by two or more linking laboratories. For the temperature range from 83.8058 K (triple point of Ar) to 933.473 K (freezing point of Al), a key comparison, CCT-K3, was carried out from 1997 to 2001 among representative laboratories in North America, Europe and Asia. Following CCT-K3, the Asia-Pacific Metrology Program Key Comparison 3 (APMP.T-K3) was organized for National Metrology Institutes in the Asia/Pacific region. NMIA (Australia) and KRISS (South Korea) provided the link between CCT-K3 and APMP.T-K3. APMP.T-K3, which took place from February 2000 to June 2003, covered the temperature range from -38.8344 °C (triple point of Hg) to 419.527 °C (freezing point of Zn), using a standard platinum resistance thermometer (SPRT) as the artefact. In June 2007 the Vietnam Metrology Institute (VMI) requested a bilateral comparison to link their SPRT calibration capabilities to APMP.T-K3, and in October 2007 the National Metrology Institute of South Africa (NMISA) agreed to provide the link to APMP.T-K3. Like APMP.T-K3, the comparison was restricted to the Hg to Zn temperature range to reduce the chance of drift in the SPRT artefact. The comparison was carried out in a participant-pilot-participant topology (with NMISA as the pilot and VMI as the participant). VMI's results in the comparison were linked to the Average Reference Values of CCT-K3 via NMISA's results in APMP.T-K3. The resistance ratios measured by VMI and NMISA at Zn, Sn, Ga and Hg fixed points agree within their combined uncertainties, and VMI's results also agree with the CCT-K3 reference values at these fixed points. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
Long History of IAM Comparisons
DOE Office of Scientific and Technical Information (OSTI.GOV)
Smith, Steven J.; Clarke, Leon E.; Edmonds, James A.
2015-04-23
Correspondence to editor: We agree with the editors that the assumptions behind models of all types, including integrated assessment models (IAMs), should be as transparent as possible. The editors were in error, however, when they implied that the IAM community is just “now emulating the efforts of climate researchers by instigating their own model inter-comparison projects (MIPs).” In fact, model comparisons for integrated assessment and climate models followed a remarkably similar trajectory. Early General Circulation Model (GCM) comparison efforts, evolved to the first Atmospheric Model Inter-comparison Project (AMIP), which was initiated in the early 1990s. Atmospheric models evolved to coupledmore » atmosphere-ocean models (AOGCMs) and results from the first Coupled Model Inter-Comparison Project (CMIP1) become available about a decade later. Results of first energy model comparison exercise, conducted under the auspices of the Stanford Energy Modeling Forum, were published in 1977. A summary of the first comparison focused on climate change was published in 1993. As energy models were coupled to simple economic and climate models to form IAMs, the first comparison exercise for IAMs (EMF-14) was initiated in 1994, and IAM comparison exercises have been on-going since this time.« less
NASA Astrophysics Data System (ADS)
Janik, Dieter; Inoue, T.; Michaud, A.
2006-01-01
This report summarizes the results and the measuring methods of an international key comparison between twelve national metrology institutes (NMIs) and is concerning the calibration factor of RF power sensors in the coaxial 3.5 mm line for frequencies up to 26 GHz. Two RF power travelling standards fitted with male PC 3.5 mm connectors were measured at seven frequencies. The following NMIs participated: NMIJ (Japan), NRC (Canada), NIST (USA), METAS (Switzerland), CSIR-NML (South Africa), NMIA (Australia), NPL (UK), SiQ (Slovenia), IEN (Italy), VNIIFTRI (Russian Federation), SPRING (Singapore) and PTB (Germany), as the pilot laboratory. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
Final report on the key comparison CCPR-K5: Spectral diffuse reflectance
NASA Astrophysics Data System (ADS)
Nadal, Maria; Eckerle, Kenneth L.; Early, Edward A.; Ohno, Yoshi
2013-01-01
The CCPR K5 key comparison on spectral diffuse reflectance was carried out in the framework of the CIPM Mutual Recognition Arrangement, by 13 national metrology institutes (MMIs) as participants. The participants were CSIR-NML (South Africa), HUT (Finland), IFA-CSIC (Spain), KRISS (Republic of Korea), MSL (New Zealand), NIM (China), NIST (United States of America), NMIJ (Japan), NPL (United Kingdom), NRC (Canada), OMH (Hungary), PTB (Germany) and VNIIOFI (Russia Federation). NIST (USA) piloted the comparison. The aim of this comparison was to check the agreement of measurement of the spectral diffuse reflectance among participants, using the measurement geometry of d/0 or 0/d in the wavelength range of 360 nm to 820 nm at 20 nm increment. The comparison was a star type comparison with the samples provided by the pilot laboratory and with the measurement sequence: Pilot-Participant-Pilot. Spectralon and matte white ceramic tiles were used as the transfer standards. Each participant received three of each type of sample and at least one sample of each type was measured three times on three separate days, and the other two samples were measured once. The report presents the description of the measurement facilities, procedures and uncertainties of all the participants as well as the results of the comparison. Measurement results from the participants and their associated uncertainties were analyzed in accordance with the Guidelines for CCPR Key Comparison Report Preparation, using weighted mean with cut-off. For the calculation of the Key Comparison Reference Value (KCRV), as agreed by the participants, the data of both samples were used for the 460 nm to 820 nm region and only the data of the Spectralon samples were used in the spectral region of 360 nm to 440 nm. The unilateral degrees of equivalence (DoE) calculated for each participant are mostly consistent within the uncertainty (k = 2) of the DoE. This international comparison of spectral diffuse reflectance shows overall good agreement among all participants. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCPR, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Species management benchmarking: outcomes over outputs in a changing operating environment.
Hogg, Carolyn J; Hibbard, Chris; Ford, Claire; Embury, Amanda
2013-03-01
Species management has been utilized by the zoo and aquarium industry, since the mid-1990s, to ensure the ongoing genetic and demographic viability of populations, which can be difficult to maintain in the ever-changing operating environments of zoos. In 2009, the Zoo and Aquarium Association Australasia reviewed their species management services, focusing on addressing issues that had arisen as a result of the managed programs maturing and operating environments evolving. In summary, the project examined resourcing, policies, processes, and species to be managed. As a result, a benchmarking tool was developed (Health Check Report, HCR), which evaluated the programs against a set of broad criteria. A comparison of managed programs (n = 98), between 2008 and 2011, was undertaken to ascertain the tool's effectiveness. There was a marked decrease in programs that were designated as weak (37 down to 13); and an increase in excellent programs (24 up to 49) between the 2 years. Further, there were significant improvements in the administration benchmarking area (submission of reports, captive management plan development) across a number of taxon advisory groups. This HCR comparison showed that a benchmarking tool enables a program's performance to be quickly assessed and any remedial measures applied. The increases observed in program health were mainly due to increased management goals being attained. The HCR will be an ongoing program, as the management of the programs increases and goals are achieved, criteria will be refined to better highlight ongoing issues and ways in which these can be resolved. © 2012 Wiley Periodicals, Inc.
NASA Astrophysics Data System (ADS)
Pozdeeva, Valentina; Chalyy, Vladimir
2014-01-01
The supplementary comparison COOMET.AUV.A-S1 for secondary calibration methods using WS1 and WS2 measurement microphones was carried out from 2009 to 2010. The results were submitted to and approved by CCAUV in April 2014. Four National Metrology Institutes took part in this comparison and are as follows: BelGIM (Belarus), VNIIFTRI (Russia), SMU (Slovakia) and DP NDI 'Sistema' (Ukraine). Three of the above NMIs (VNIIFTRI, SMU and DP NDI 'Sistema') had earlier participated in COOMET key comparisons and one NMI (VNIIFTRI) had also participated in CCAUV key comparisons. The Comparison Reference Values were calculated as the weighted mean values from results obtained by three institutes. The comparison results show agreement for all participants in the frequency range from 20 Hz to 12.5 kHz for WS1 microphones, and in the frequency range from 20 Hz to 16 kHz for WS2 microphones. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCAUV, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
ERIC Educational Resources Information Center
Langdon, Jonathan
2011-01-01
Ghana has been identified as an important example of democracy in Africa, yet the story of this democratic success overlooks the crucial role social movement activism and learning have played in locally reconfiguring and deepening what democracy means. A key dimension of this overlooked-story is ongoing efforts to contest both local and global…
ERIC Educational Resources Information Center
Shah, Mahsood; Nair, Chenicheri Sid
2011-01-01
The renewal of quality assurance in Australian higher education comes at a time when the higher education sectors in Australia and around the world are experiencing a number of key challenges. These include: ongoing decline in public funding of universities; the massification of higher education and demand for it during global recession;…
ERIC Educational Resources Information Center
Daniel, Ryan; Daniel, Leah
2015-01-01
This article reflects on ongoing research-led teaching in the area of creative industries in higher education. Specifically it reports on key work-integrated learning strategies designed to better prepare graduates for the employment sector. The creative industries sector is complex and competitive, characterized by non-linear career paths driven…
ERIC Educational Resources Information Center
Shearer, Rick L.
2009-01-01
Theory building is complex and ongoing. Theories need to be constantly tested and the underlying constructs explored, as knowledge of a field evolves. This study, which is in support of Moore's (1980, 1993) theory of transactional distance, is exploratory and descriptive, and focuses on one of the key variables in the theory dialogue. As…
Research Trends in Mobile Learning in Higher Education: A Systematic Review of Articles (2011-2015)
ERIC Educational Resources Information Center
Krull, Greig; Duart, Josep M.
2017-01-01
The potential and use of mobile devices in higher education has been a key issue for educational research and practice since the widespread adoption of these devices. Due to the evolving nature and affordances of mobile technologies, it is an area that requires ongoing investigation. This study aims to identify emerging trends in mobile learning…
ERIC Educational Resources Information Center
Stichter, Janine P.; Riley-Tillman, T. Chris
2014-01-01
Systematic Direct Observation (SDO) has played a pivotal role in the field of Emotional and/or Behavioral Disorders (EBD) since its inception as a key part of understanding more about the behaviors, contexts that impact them, and the effective supports necessary for this population. This methodology is an ongoing charge for everyone. The authors…
ERIC Educational Resources Information Center
Gould, Madelyn S.; Munfakh, Jimmie L. H.; Kleinman, Marjorie; Lake, Alison M.
2012-01-01
Linking at-risk callers to ongoing mental health care is a key goal of crisis hotline interventions that has not often been addressed in evaluations of hotlines' effectiveness. We conducted telephone interviews with 376 suicidal and 278 nonsuicidal crisis callers to the National Suicide Prevention Lifeline (Lifeline) to assess rates of mental…
ERIC Educational Resources Information Center
Taylor, Tony; Collins, Sue
2012-01-01
This article critiques popular assumptions that underlie the ongoing politicisation of school history curriculum as an agent of social identity and behaviour. It raises some key research questions which need further investigation and suggests a potential methodology for establishing evidence-based understanding of the relationship between history…
Drawing Conclusions: Confusion between Data and Theory in the Traumatic Memory Debate
ERIC Educational Resources Information Center
Silberg, Joyanna
2003-01-01
This paper examines one of the chief problems in the ongoing debate about the nature and prevalence of the various memory mechanisms that may operate in determining whether a victim/survivor of childhood sexual abuse (CSA) will have delayed recall of the victimization. One of the key problems in the debate about delayed or suppressed memory of…
Teacher as Learner: A Personal Reflection on a Short Course for South African University Educators
ERIC Educational Resources Information Center
Clowes, Lindsay
2013-01-01
Higher education is understood to play a critical role in ongoing processes of social transformation in post-apartheid South Africa through the production of graduates who are critical and engaged citizens. A key challenge is that institutions of higher education are themselves implicated in reproducing the very hierarchies they hope to transform.…
ERIC Educational Resources Information Center
Iwasaki, Yoshitaka; Hopper, Tristan; Whelan, Patricia
2017-01-01
This short communication provides our insights into how or in what ways educators can more effectively support aspiration of at-risk/high-risk youth toward meaningful education. These are informed by the key learnings from our ongoing youth engagement research. Those insights emphasize the importance of "meaningful engagement of youth"…
Trade Barriers: To Invest, or Not to Invest, in a Trade as a Career
ERIC Educational Resources Information Center
Alloway, Nola; Dalley-Trim, Leanne; Patterson, Annette; Walker, Karen
2006-01-01
This paper highlights on-going concern in Australia about the contested terrain of skills shortages, particularly as they apply to traditional trades. The paper reports on a school-based study of student career choice that was undertaken for the federal government to inform its deliberations. Drawing on the study, the paper examines key issues…
Re-Assessing Practice: Visual Art, Visually Impaired People and the Web.
ERIC Educational Resources Information Center
Howell, Caro; Porter, Dan
The latest development to come out of ongoing research at Tate Modern, London's new museum of modern art, is i-Map art resources for blind and partially sighted people that are delivered online. Currently i-Map explores the work of Matisse and Picasso, their innovations, influences and personal motivations, as well as key concepts in modern art.…
ERIC Educational Resources Information Center
Hope, Kempe Ronald, Sr.
2013-01-01
The purpose of this article is to provide an assessment and analysis of public sector performance contracting as a performance management tool in Kenya. It aims to demonstrate that performance contracting remains a viable and important tool for improving public sector performance as a key element of the on-going public sector transformation…
ERIC Educational Resources Information Center
Walters, Simon R.; Payne, Deborah; Schluter, Philip J.; Thomson, Rex W.
2015-01-01
The childhood years are highlighted as a crucial time when ongoing participation in physical activity can be nurtured and maintained. The nurturing of a child's proclivity to participate in organised sport normally falls into the domain of adults. While both parents and coaches have been identified as key influences on children's enjoyment of…
The Creation of the University of Bedfordshire: An Ongoing Project
ERIC Educational Resources Information Center
Franklin, Jim; Robinson, Kate
2010-01-01
"The key needs of Bedfordshire, to improve the participation of its people in higher education and to regenerate its economy, will be best served by a new major access and employment oriented University." This vision statement was adopted by the Board of Governors of the University of Luton on 9 December 2005 on taking the decision to go…
ERIC Educational Resources Information Center
Ryan, Joseph; Brockmann, Frank
2009-01-01
Equating is an essential tool in educational assessment due the critical role it plays in several key areas: establishing validity across forms and years; fairness; test security; and, increasingly, continuity in programs that release items or require ongoing development. Although the practice of equating is rooted in long standing practices that…
ERIC Educational Resources Information Center
Knight, Jim
2009-01-01
In the past decade, interest in the form of professional learning loosely described as coaching has exploded. This growing interest in coaching is likely fueled by educators' recognition that traditional one-shot approaches to professional development--where teachers hear about practices but do not receive follow-up support--are ineffective at…
Developing a Framework for Monitoring Child Poverty: Results from a Study in Uganda
ERIC Educational Resources Information Center
Witter, Sophie
2004-01-01
In 2002 Save the Children UK carried out a study of child poverty in Uganda, as part of the on-going Uganda Participatory Poverty Assessment Programme. Using participants from all regions of the country, the researchers asked children about their perceptions of poverty and anti-poverty strategies, as well as questioning adult key informants about…
Caught between the Ethnic Sides: Children Growing up in a Divided Post-War Community
ERIC Educational Resources Information Center
Ajdukovic, Dean; Biruski, Dinka Corkalo
2008-01-01
The war-related process of disintegration of a highly integrated and multi-ethnic community is described using a series of studies done in the city of Vukovar (Croatia) as a case example. After analyzing the key points of the community social breakdown, the three roots of ongoing ethnic division are explored: the feelings of being betrayed by…
EURAMET.T-K7 Key Comparison of Water Triple-Point Cells
NASA Astrophysics Data System (ADS)
Peruzzi, A.; Bosma, R.; Kerkhof, O.; Rosenkranz, P.; Del Campo Maldonado, M. D.; Strnad, R.; Nielsen, J.; Anagnostou, M.; Veliki, T.; Zvizdic, D.; Grudnewicz, E.; Nedea, M.; Neagu, D. M.; Steur, P.; Filipe, E.; Lobo, I.; Antonsen, I.; Renaot, E.; Heinonen, M.; Weckstrom, T.; Bojkovski, J.; Turzo-Andras, E.; Nemeth, S.; White, M.; Tegeler, E.; Dobre, M.; Duris, S.; Kartal Dogan, A.; Uytun, A.; Augevicius, V.; Pauzha, A.; Pokhodun, A.; Simic, S.
2011-12-01
The results of a EURAMET key comparison of water triple-point cells (EURAMET.T-K7) are reported. The equipment used, the measuring conditions applied, and the procedures adopted for the water triple-point measurement at the participating laboratories are synthetically presented. The definitions of the national reference for the water triple-point temperature adopted by each laboratory are disclosed. The multiplicity of degrees of equivalence arising for the linking laboratories with respect to the "mother" comparison CCT-K7 is discussed in detail.
Key comparison CCPR-K1.a as an interlaboratory comparison of correlated color temperature
NASA Astrophysics Data System (ADS)
Kärhä, P.; Vaskuri, A.; Pulli, T.; Ikonen, E.
2018-02-01
We analyze the results of spectral irradiance key comparison CCPR-K1.a for correlated color temperature (CCT). For four participants out of 13, the uncertainties of CCT, calculated using traditional methods, not accounting for correlations, would be too small. The reason for the failure of traditional uncertainty calculation is spectral correlations, producing systematic deviations of the same sign over certain wavelength regions. The results highlight the importance of accounting for such correlations when calculating uncertainties of spectrally integrated quantities.
Final report of CCQM-K130 nitrogen mass fraction measurements in glycine
NASA Astrophysics Data System (ADS)
Medvedevskikh, Maria; Krasheninina, Maria; do Rego, Eliane C. P.; Wollinger, Wagner; Monteiro, Tânia M.; de Carvalho, Lucas J.; Acco Garcia, Steve Ali; Haraldsson, Conny; Rodriguez, M. Alejandra; Rodriguez, Gabriela; Salvo, Karino; Gavrilkin, Vladimir; Kulyk, Sergij; Samuel, Laly
2017-01-01
CCQM key comparison K-130 in the field of nitrogen mass fracton has been performed by the Inorganic Analysis Working Group (IAWG) of the Consultative Committee for Amount of Substance (CCQM). The aim of this key comparison CCQM-K130 is to support National Measurement Institutes (NMIs) and Designated Institutes (DIs) to demonstrate the validity of the procedures the employed for determination of nitrogen mass fraction in glycine. Mass fraction of nitrogen is very important pointer because the results of these measurements are often used for determination of protein mass fraction that is an important indicator of the quality of the vast majority of food products and raw materials, in particular dry milk powder. Proteins-enzymes catalyze chemical reactions, protein along with fats and carbohydrates is one of the indicators characterizing the energy value of food, so its definition is mandatory for all food products. The study material for this key comparison has been selected to be representative as one of the aminoacid - the simplest part of the protein. Glycine is an amino acid, single acid that does not have any isomers (melting point -290 °C specific heat of evaporation - 528,6 J/kg; specific melting heat - 981,1 J/kg; pKa - 2, 34, molar mass - 75,07 g/mol, density - 1,607 g/cm3). Ural Scientific Research Institute for Metrology (UNIIM) acted as the coordinating laboratory of this comparison. Nine NMIs participated in this key comparison and one NMI participated in Pilot study that was condacted in parallel. Report A contains the results of key comparison and pilot study. The results of Pilot study were excluded from the Report B Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Nel, R.; Avison, J.; Harris, P.; Blabla, M.; Hämäläinen, J.
2017-01-01
The degrees of equivalence of the AFRIMETS.AUV.A-K5 regional key comparison are reported here as the final report. The scope of the comparison covered the complex pressure sensitivities of two LS1P microphones over the frequency range 2 Hz to 10 kHz in accordance with IEC 61094-2: 2009. Four national metrology institutes from two different regional metrology organisations participated in the comparison. Two LS1P microphones were circulated simultaneously to all the participants in a circular configuration. One of the microphones sensitivity shifted and all results associated with this microphone were subsequently excluded from further analysis and linking. The AFRIMETS.AUV.A-K5 comparison results were linked to the CCAUV.A-K5 comparison results via dual participation in the CCAUV.A-K5 and AFRIMETS.AUV.A-K5 comparisons. The degrees of equivalence, linked to the CCAUV.A-K5 comparison, were calculated for all participants of this comparison. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCAUV, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Kocas, I.; Sabuga, W.; Bergoglio, M.; Eltaweel, A.; Korasie, C.; Farar, P.; Setina, J.; Waller, B.; Durgut, Y.
2015-01-01
The regional key comparison EURAMET.M.P-K13 for pressure measurements in liquid media from 50 MPa to 500 MPa was piloted by the TÜBİTAK UME Pressure Group Laboratories, Turkey. The transfer standard was a DH-Budenberg pressure balance with a free deformation piston-cylinder unit of 2 mm2 nominal effective area. Six laboratories from the EURAMET region, namely PTB, INRIM, SMU, IMT, NPL and UME, and two laboratories from the AFRIMETS region, NIS and NMISA participated in this comparison. Participant laboratories and countries are given in the bottom of the page. PTB participated in this comparison to provide a link to corresponding 500 MPa CCM key comparison CCM.P-K13. The results of all participants excepting NMISA and NPL were found to be consistent with the reference value of the actual comparison and of CCM.P-K13 within their claimed uncertainties (k = 2), at all pressures. Compared in pairs all laboratories with exception of NPL and NMISA demonstrate their agreement with each other within the expanded uncertainties (k = 2) at all pressures. The results are therefore considered to be satisfactory. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Ireland, Gareth; North, Matthew R.; Petropoulos, George P.; Srivastava, Prashant K.; Hodges, Crona
2015-04-01
Acquiring accurate information on the spatio-temporal variability of soil moisture content (SM) and evapotranspiration (ET) is of key importance to extend our understanding of the Earth system's physical processes, and is also required in a wide range of multi-disciplinary research studies and applications. The utility and applicability of Earth Observation (EO) technology provides an economically feasible solution to derive continuous spatio-temporal estimates of key parameters characterising land surface interactions, including ET as well as SM. Such information is of key value to practitioners, decision makers and scientists alike. The PREMIER-EO project recently funded by High Performance Computing Wales (HPCW) is a research initiative directed towards the development of a better understanding of EO technology's present ability to derive operational estimations of surface fluxes and SM. Moreover, the project aims at addressing knowledge gaps related to the operational estimation of such parameters, and thus contribute towards current ongoing global efforts towards enhancing the accuracy of those products. In this presentation we introduce the PREMIER-EO project, providing a detailed overview of the research aims and objectives for the 1 year duration of the project's implementation. Subsequently, we make available the initial results of the work carried out herein, in particular, related to an all-inclusive and robust evaluation of the accuracy of existing operational products of ET and SM from different ecosystems globally. The research outcomes of this project, once completed, will provide an important contribution towards addressing the knowledge gaps related to the operational estimation of ET and SM. This project results will also support efforts ongoing globally towards the operational development of related products using technologically advanced EO instruments which were launched recently or planned be launched in the next 1-2 years. Key Words: PREMIER-EO, HPC Wales, Soil Moisture, Evapotranspiration, , Earth Observation
Programmatic Impact of 5 Years of Mortality Surveillance of New York City Homeless Populations
Marder, Dova; Begier, Elizabeth; Gutkovich, Alexander; Mos, Robert; Griffin, Angela; Zimmerman, Regina; Madsen, Ann
2013-01-01
A homeless mortality surveillance system identifies emerging trends in the health of the homeless population and provides this information to key stakeholders in a timely and ongoing manner to effect evidence-based, programmatic change. We describe the first 5 years of the New York City homeless mortality surveillance system and, for the first time in peer-reviewed literature, illustrate the impact of key elements of sustained surveillance (i.e., timely dissemination of aggregate mortality data and real-time sharing of information on individual homeless decedents) on the programs of New York City’s Department of Homeless Services. These key elements had a positive impact on the department’s programs that target sleep-related infant deaths and hypothermia, drug overdose, and alcohol-related deaths among homeless persons. PMID:24148068
The comparison and analysis of extracting video key frame
NASA Astrophysics Data System (ADS)
Ouyang, S. Z.; Zhong, L.; Luo, R. Q.
2018-05-01
Video key frame extraction is an important part of the large data processing. Based on the previous work in key frame extraction, we summarized four important key frame extraction algorithms, and these methods are largely developed by comparing the differences between each of two frames. If the difference exceeds a threshold value, take the corresponding frame as two different keyframes. After the research, the key frame extraction based on the amount of mutual trust is proposed, the introduction of information entropy, by selecting the appropriate threshold values into the initial class, and finally take a similar mean mutual information as a candidate key frame. On this paper, several algorithms is used to extract the key frame of tunnel traffic videos. Then, with the analysis to the experimental results and comparisons between the pros and cons of these algorithms, the basis of practical applications is well provided.
Yang, Zhihong; Lin, James; Zhang, John; Fong, Wai Ieng; Li, Pei; Zhao, Rong; Liu, Xiaohong; Podevin, William; Kuang, Yanping; Liu, Jiaen
2015-06-23
Recent advances in next-generation sequencing (NGS) have provided new methods for preimplantation genetic screening (PGS) of human embryos from in vitro fertilization (IVF) cycles. However, there is still limited information about clinical applications of NGS in IVF and PGS (IVF-PGS) treatments. The present study aimed to investigate the effects of NGS screening on clinical pregnancy and implantation outcomes for PGS patients in comparison to array comparative genomic hybridization (aCGH) screening. This study was performed in two phases. Phase I study evaluated the accuracy of NGS for aneuploidy screening in comparison to aCGH. Whole-genome amplification (WGA) products (n = 164) derived from previous IVF-PGS cycles (n = 38) were retrospectively analyzed with NGS. The NGS results were then compared with those of aCGH. Phase II study further compared clinical pregnancy and implantation outcomes between NGS and aCGH for IVF-PGS patients. A total of 172 patients at mean age 35.2 ± 3.5 years were randomized into two groups: 1) NGS (Group A): patients (n = 86) had embryos screened with NGS and 2) aCGH (Group B): patients (n = 86) had embryos screened with aCGH. For both groups, blastocysts were vitrified after trophectoderm biopsy. One to two euploid blastocysts were thawed and transferred to individual patients primarily based on the PGS results. Ongoing pregnancy and implantation rates were compared between the two study groups. NGS detected all types of aneuploidies of human blastocysts accurately and provided a 100 % 24-chromosome diagnosis consistency with the highly validated aCGH method. Moreover, NGS screening identified euploid blastocysts for transfer and resulted in similarly high ongoing pregnancy rates for PGS patients compared to aCGH screening (74.7 % vs. 69.2 %, respectively, p >0.05). The observed implantation rates were also comparable between the NGS and aCGH groups (70.5 % vs. 66.2 %, respectively, p >0.05). While NGS screening has been recently introduced to assist IVF patients, this is the first randomized clinical study on the efficiency of NGS for preimplantation genetic screening in comparison to aCGH. With the observed high accuracy of 24-chromosome diagnosis and the resulting high ongoing pregnancy and implantation rates, NGS has demonstrated an efficient, robust high-throughput technology for PGS.
Dougherty, Scott; Beaton, Andrea; Nascimento, Bruno R; Zühlke, Liesl J; Khorsandi, Maziar; Wilson, Nigel
2018-01-01
Rheumatic heart disease (RHD) has long receded as a significant threat to public health in high-income countries. In low-resource settings, however, the specter of RHD remains unabated, as exemplified by recent data from the Global Burden of Diseases Study. There are many complex reasons for this ongoing global disparity, including inadequate data on disease burden, challenges in effective advocacy, ongoing poverty and inequality, and weak health systems, most of which predominantly affect developing nations. In this review, we discuss how each of these acts as a core challenge in RHD prevention and control. We then examine key lessons learnt from successful control programs in the past and highlight resources that have been developed to help create strong national RHD control programs.
Dougherty, Scott; Beaton, Andrea; Nascimento, Bruno R; Zühlke, Liesl J; Khorsandi, Maziar; Wilson, Nigel
2018-01-01
Rheumatic heart disease (RHD) has long receded as a significant threat to public health in high-income countries. In low-resource settings, however, the specter of RHD remains unabated, as exemplified by recent data from the Global Burden of Diseases Study. There are many complex reasons for this ongoing global disparity, including inadequate data on disease burden, challenges in effective advocacy, ongoing poverty and inequality, and weak health systems, most of which predominantly affect developing nations. In this review, we discuss how each of these acts as a core challenge in RHD prevention and control. We then examine key lessons learnt from successful control programs in the past and highlight resources that have been developed to help create strong national RHD control programs. PMID:29440834
Problems of quality and equity in pain management: exploring the role of biomedical culture.
Crowley-Matoka, Megan; Saha, Somnath; Dobscha, Steven K; Burgess, Diana J
2009-10-01
To explore how social scientific analyses of the culture of biomedicine may contribute to advancing our understanding of ongoing issues of quality and equity in pain management. Drawing upon the rich body of social scientific literature on the culture of biomedicine, we identify key features of biomedical culture with particular salience for pain management. We then examine how these cultural features of biomedicine may shape key phases of the pain management process in ways that have implications not just for quality, but for equity in pain management as well. We bring together a range of literatures in developing our analysis, including literatures on the culture of biomedicine, pain management and health care disparities. We surveyed the relevant literatures to identify and inter-relate key features of biomedical culture, key phases of the pain management process, and key dimensions of identified problems with suboptimal and inequitable treatment of pain. We identified three key features of biomedical culture with critical implications for pain management: 1) mind-body dualism; 2) a focus on disease vs illness; and 3) a bias toward cure vs care. Each of these cultural features play a role in the key phases of pain management, specifically pain-related communication, assessment and treatment decision-making, in ways that may hinder successful treatment of pain in general -- and of pain patients from disadvantaged groups in particular. Deepening our understanding of the role of biomedical culture in pain management has implications for education, policy and research as part of ongoing efforts to ameliorate problems in both quality and equity in managing pain. In particular, we suggest that building upon the existing the cultural competence movement in medicine to include fostering a deeper understanding of biomedical culture and its impact on physicians may be useful. From a policy perspective, we identify pain management as an area where the need for a shift to a more biopsychosocial model of health care is particularly pressing, and suggest prioritization of inter-disciplinary, multimodal approaches to pain as one key strategy in realizing this shift. Finally, in terms of research, we identify the need for empirical research to assess aspects of biomedical culture that may influence physician's attitudes and behaviors related to pain management, as well as to explore how these cultural values and their effects may vary across different settings within the practice of medicine.
KEY COMPARISON: Final report of the SIM 60Co absorbed-dose-to-water comparison SIM.RI(I)-K4
NASA Astrophysics Data System (ADS)
Ross, C. K.; Shortt, K. R.; Saravi, M.; Meghzifene, A.; Tovar, V. M.; Barbosa, R. A.; da Silva, C. N.; Carrizales, L.; Seltzer, S. M.
2008-01-01
Transfer chambers were used to compare the standards for 60Co absorbed dose to water maintained by seven laboratories. Six of the laboratories were members of the Sistema Interamericano de Metrología (SIM) regional metrology organization while the seventh was the International Atomic Energy Agency (IAEA) laboratory in Vienna. The National Research Council (NRC) acted as the pilot laboratory for the comparison. Because of the participation of laboratories holding primary standards, the comparison results could be linked to the key comparison reference value maintained by the Bureau International des Poids et Mesures (BIPM). The results for all laboratories were within the expanded uncertainty (two standard deviations) of the reference value. The estimated relative standard uncertainty on the comparison between any pair of laboratories ranged from 0.6% to 1.4%. The largest discrepancy between any two laboratories was 1.3%. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI Section I, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
KEY COMPARISON: Final report of the SIM 60Co air-kerma comparison SIM.RI(I)-K1
NASA Astrophysics Data System (ADS)
Ross, C. K.; Shortt, K. R.; Saravi, M.; Meghzifene, A.; Tovar, V. M.; Barbosa, R. A.; da Silva, C. N.; Carrizales, L.; Seltzer, S. M.
2008-01-01
Transfer chambers were used to compare the standards for 60Co air kerma maintained by seven laboratories. Six of the laboratories are members of the Sistema Interamericano de Metrología (SIM) regional metrology organization while the seventh is the International Atomic Energy Agency (IAEA) laboratory in Vienna. The National Research Council (NRC) acted as the pilot laboratory for the comparison. Because of the participation of laboratories holding primary standards, the comparison results could be linked to the key comparison reference value maintained by the Bureau International des Poids et Mesures (BIPM). The results for all laboratories were within the expanded uncertainty (two standard deviations) of the reference value. The estimated relative standard uncertainty of the comparison between any pair of laboratories ranged from 0.5% to 1.0%. The largest discrepancy between any two laboratories was 1.0%. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI Section I, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Pokhodun, A. I.
2010-01-01
In the framework of the CIPM MRA, a first COOMET comparison "Comparison of the ITS-90 realizations in the range from 0.01 °C to 429.7485 °C (from the triple point of water to the freezing point of zinc)", registered in the KCDB under the identifier "COOMET.T-K3", was carried out in 2005-2007. Four national metrology institutes took part in this comparison: VNIIM (Russian Federation), SMU (Slovakia), BelGIM (Republic of Belarus) and NSC IM (Ukraine), and two of them (VNIIM and SMU) ensured the linkage with key comparisons CCT-K3 and CCT-K4, in order to disseminate the metrological equivalence to the measurement standards of NSC IM and BelGIM. NSC IM, however, had to withdraw its results, and at the meeting of Technical Committee T-10 of COOMET it was decided to carry out a supplementary bilateral comparison between VNIIM and the NSC IM for realization of the ITS-90 in the same range of temperature. This was registered in the KCDB under the identifier COOMET.T-S1 and measurements were performed in 2008-2009. From the results presented in this report, it is possible to draw the conclusion that the COOMET supplementary comparison COOMET.T-S1 demonstrates the CMC uncertainties claimed by the NSC IM for the melting point of gallium 0.236 mK (k = 2), and the freezing points of indium 1.040 mK (k = 2), tin 0.858 mK (k = 2) and zinc 0.944 mK (k = 2). In September 2012 the Working Group on key Comparisons (WG 7) of the CCT upgraded this comparison to a COOMET key comparison of the 'CCT-K3' type. It is now identified as COOMET.T-K3.1. In April 2013 this report was superseded by item 03006 in the Technical Supplement of 2013. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
ERIC Educational Resources Information Center
Ebersohn, Liesel; Ferreira, Ronel
2012-01-01
In an ongoing longitudinal intervention study (STAR) we found that, although similarities existed in the way teachers promoted resilience, rural schools (in comparison to other STAR case schools) took longer to implement strategies to buoy support and found it difficult to sustain such support. Using rurality we wanted to understand how forces,…
Wake Sensor Evaluation Program and Results of JFK-1 Wake Vortex Sensor Intercomparisons
NASA Technical Reports Server (NTRS)
Barker, Ben C., Jr.; Burnham, David C.; Rudis, Robert P.
1997-01-01
The overall approach should be to: (1) Seek simplest, sufficiently robust, integrated ground based sensor systems (wakes and weather) for AVOSS; (2) Expand all sensor performance cross-comparisons and data mergings in on-going field deployments; and (3) Achieve maximal cost effectiveness through hardware/info sharing. An effective team is in place to accomplish the above tasks.
ERIC Educational Resources Information Center
Bayer, Betty L.
2017-01-01
Problem and Purpose: Much research over several decades has established the importance of ongoing professional learning for teachers and has identified what effective professional learning should look like. Little research has been done, however, on the professional learning practices of teachers in faith-based schools, and few studies have…
ERIC Educational Resources Information Center
Gokce, Asiye Toker; Celep, Cevat
2011-01-01
Managing people requires ongoing living in a harmony and to educate citizens who would support this status. It is not easy to continue the existence of management which can perform different cultures. The different management style is different educational systems. The management style also directly affects the country's educational philosophy.…
USDA-ARS?s Scientific Manuscript database
Ongoing developments and cost decreases in next-generation sequencing (NGS) technologies have led to an increase in their application, which has greatly enhanced the fields of genetics and genomics. Mapping sequence reads onto a reference genome is a fundamental step in the analysis of NGS data. Eff...
Getting Clued In: Inferential Processing and Comprehension Monitoring in Boys with ADHD
ERIC Educational Resources Information Center
Berthiaume, Kristen S.; Lorch, Elizabeth P.; Milich, Richard
2010-01-01
Objective: The present study examines the ability of children with ADHD to make inferences and monitor ongoing understanding of texts, to shed light on their academic difficulties. Method: A total of 29 boys with ADHD and 41 comparison boys between the ages of 7 and 12 participated. Three tasks measure how boys create and evaluate inferences,…
NASA Astrophysics Data System (ADS)
Kessler, C.; Burns, D.; Durný, N.
2018-01-01
The first direct comparison of the standards for air kerma of the Slovak Institute of Metrology (SMU), Slovakia and of the Bureau International des Poids et Mesures (BIPM) was carried out in the 137Cs radiation beam of the BIPM in June 2017. The comparison result, evaluated as a ratio of the SMU and the BIPM standards for air kerma, is 1.0051 with a combined standard uncertainty of 2.7 × 10-3. The results for an indirect comparison made at the same time are consistent with the direct results at the level of 2 parts in 104. The results are analysed and presented in terms of degrees of equivalence, suitable for entry in the BIPM key comparison database. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Kessler, C.; Burns, D.; Machula, G.
2018-01-01
A comparison of the standards for air kerma of the Hungarian Trade Licensing Office (MKEH), Hungary and of the Bureau International des Poids et Mesures (BIPM) was carried out in the 60Co radiation beam of the BIPM in March 2016. The comparison result, evaluated as a ratio of the MKEH and the BIPM standards for air kerma, is 1.0047 with a combined standard uncertainty of 1.9 × 10-3. The results for an indirect comparison made at the same time are consistent with the direct results at the level of 2.6 parts in 103. The results are analysed and presented in terms of degrees of equivalence, suitable for entry in the BIPM key comparison database. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
SIM key comparison for luminous flux. SIM.PR-K4
NASA Astrophysics Data System (ADS)
Matamoros, Carlos H.; Ohno, Yoshi; Zwinkels, Joanne; Cogno, Jorge A.; Couceiro, Iakyra B.
2016-01-01
In compliance with the established BIPM and CCPR policies and guidelines on comparisons, the SIM Photometry and Radiometry Working Group decided to conduct a key comparison on total luminous flux in order to provide an opportunity for its member National Metrology Institutes (NMIs) that did not participate in the CCPR-K4 comparison, to get a link to the reference value obtained for this quantity (the lumen) and to derive the corresponding degrees of equivalence. This SIM.PR-K4 was piloted by Centro Nacional de Metrología (CENAM), the NMI of Mexico and included the participation of five laboratories: CENAM (Mexico), INTI (Argentina), INMETRO (Brazil), NIST (USA, linking lab), and NRC (Canada, linking lab). The comparison, conducted in star type scheme, was run using three to four lamps per participant, and results are given in this report, including the unilateral degrees of equivalence. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCPR, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Meyer, C. W.; Hill, K. D.
2015-01-01
A Regional Metrology Organization (RMO) Key Comparison of dew/frost point temperatures was carried out by the National Institute of Standards and Technology (NIST, USA) and the National Research Council (NRC, Canada) between December 2014 and April 2015. The results of this comparison are reported here, along with descriptions of the humidity laboratory standards for NIST and NRC and the uncertainty budget for these standards. This report also describes the protocol for the comparison and presents the data acquired. The results are analyzed, determining degree of equivalence between the dew/frost-point standards of NIST and NRC. This paper is the final report of the comparison including analysis of the uncertainty of measurement results. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT WG-KC, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Bell, S.; Stevens, M.; Abe, H.; Benyon, R.; Bosma, R.; Fernicola, V.; Heinonen, M.; Huang, P.; Kitano, H.; Li, Z.; Nielsen, J.; Ochi, N.; Podmurnaya, O. A.; Scace, G.; Smorgon, D.; Vicente, T.; Vinge, A. F.; Wang, L.; Yi, H.
2015-01-01
A key comparison in dew-point temperature was carried out among the national standards held by NPL (pilot), NMIJ, INTA, VSL, INRIM, MIKES, NIST, NIM, VNIIFTRI-ESB and NMC. A pair of condensation-principle dew-point hygrometers was circulated and used to compare the local realisations of dew point for participant humidity generators in the range -50 °C to +20 °C. The duration of the comparison was prolonged by numerous problems with the hygrometers, requiring some repairs, and several additional check measurements by the pilot. Despite the problems and the extended timescale, the comparison was effective in providing evidence of equivalence. Agreement with the key comparison reference value was achieved in the majority of cases, and bilateral degrees of equivalence are also reported. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
McBride, Dawn M; Abney, Drew H
2012-01-01
We examined multi-process (MP) and transfer-appropriate processing descriptions of prospective memory (PM). Three conditions were compared that varied the overlap in processing type (perceptual/conceptual) between the ongoing and PM tasks such that two conditions involved a match of perceptual processing and one condition involved a mismatch in processing (conceptual ongoing task/perceptual PM task). One of the matched processing conditions also created a focal PM task, whereas the other two conditions were considered non-focal (Einstein & McDaniel, 2005). PM task accuracy and ongoing task completion speed in baseline and PM task conditions were measured. Accuracy results indicated a higher PM task completion rate for the focal condition than the non-focal conditions, a finding that is consistent with predictions made by the MP view. However, reaction time (RT) analyses indicated that PM task cost did not differ across conditions when practice effects are considered. Thus, the PM accuracy results are consistent with a MP description of PM, but RT results did not support the MP view predictions regarding PM cost.
Therapeutic Plasma Transfusion in Bleeding Patients: A Systematic Review.
Levy, Jerrold H; Grottke, Oliver; Fries, Dietmar; Kozek-Langenecker, Sibylle
2017-04-01
Plasma products, including fresh frozen plasma, are administered extensively in a variety of settings from massive transfusion to vitamin K antagonist reversal. Despite the widespread use of plasma as a hemostatic agent in bleeding patients, its effect in comparison with other available choices of hemostatic therapies is unclear. We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, PubMed Central, and databases of ongoing trials for randomized controlled trials that assessed the efficacy and/or safety of therapeutic plasma as an intervention to treat bleeding patients compared with other interventions or placebo. Of 1243 unique publications retrieved in our initial search, no randomized controlled trials were identified. Four nonrandomized studies described the effect of therapeutic plasma in bleeding patients; however, data gathered from these studies did not allow for comparison with other therapeutic interventions primarily as a result of the low number of patients and the use of different (or lack of) comparators. We identified two ongoing trials investigating the efficacy and safety of therapeutic plasma, respectively; however, no data have been released as yet. Although plasma is used extensively in the treatment of bleeding patients, evidence from randomized controlled trials comparing its effect with those of other therapeutic interventions is currently lacking.
NASA Astrophysics Data System (ADS)
Benková, Miroslava; Makovnik, Stefan; Mickan, Bodo; Arias, Roberto; Chahine, Khaled; Funaki, Tatsuya; Li, Chunhui; Choi, Hae Man; Seredyuk, Denys; Su, Chun-Min; Windenberg, Christophe; Wright, John
2014-01-01
The comparison CCM.FF-K6.2011 was organized for the purpose of determination of the degree of equivalence of the national standards for low-pressure gas flow measurement over the range (2 to 100) m3/h. A rotary gas meter was used as a transfer standard. The measurements were provided at prescribed reference conditions. Eleven laboratories from four RMOs participated in this key comparison—EURAMET: PTB, Germany; SMU, Slovakia; LNE-LADG, France; SIM: NIST, USA; CENAM, Mexico; APMP: NMIJ AIST Japan; KRISS, Korea; NMI, Australia; NIM, China; CMS, Chinese Taipei; COOMET: GP GP Ivano-Frankivs'kstandart-metrologia, Ukraine and all participants reported independent traceability chains to the SI. All results were used in the determination of the key comparison reference value (KCRV) and the uncertainty of the KCRV. The reference value was determined at each flow separately following procedure A presented by M G Cox. The degree of equivalence with the KCRV was also calculated for each flow and laboratory. All reported results were consistent with the KCRV. This KCRV can now be used in the further regional comparisons. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Williams, John W; Jackson, George L; Powers, Benjamin J; Chatterjee, Ranee; Bettger, Janet Prvu; Kemper, Alex R; Hasselblad, Vic; Dolor, Rowena J; Irvine, R Julian; Heidenfelder, Brooke L; Kendrick, Amy S; Gray, Rebecca
2012-01-01
OBJECTIVES As part of the Closing the Quality Gap: Revisiting the State of the Science series of the Agency for Healthcare Research and Quality (AHRQ), this systematic review sought to identify completed and ongoing evaluations of the comprehensive patient-centered medical home (PCMH), summarize current evidence for this model, and identify evidence gaps. DATA SOURCES We searched PubMed®, CINAHL®, and the Cochrane Database of Systematic Reviews for published English-language studies, and a wide variety of databases and Web resources to identify ongoing or recently completed studies. REVIEW METHODS Two investigators per study screened abstracts and full-text articles for inclusion, abstracted data, and performed quality ratings and evidence grading. Our functional definition of PCMH was based on the definition used by AHRQ. We included studies that explicitly claimed to be evaluating PCMH and those that did not but which met our functional definition. RESULTS Seventeen studies with comparison groups evaluated the effects of PCMH (Key Question [KQ] 1). Older adults in the United States were the most commonly studied population (8 of 17 studies). PCMH interventions had a small positive impact on patient experiences (including patient-perceived care coordination) and small to moderate positive effects on preventive care services (moderate strength of evidence [SOE]). Staff experiences were also improved by a small to moderate degree (low SOE). There were too few studies to estimate effects on clinical or most economic outcomes. Twenty-one of 27 studies reported approaches that addressed all 7 major PCMH components (KQ 2), including team-based care, sustained partnership, reorganized care or structural changes to care, enhanced access, coordinated care, comprehensive care, and a systems-based approach to quality. A total of 51 strategies were used to address the 7 major PCMH components. Twenty-two of 27 studies reported information on financial systems used to implement PCMH, implementation strategies, and/or organizational learning strategies for implementing PCMH (KQ 3). The 31 studies identified in the horizon scan of ongoing PCMH studies (KQ 4) were broadly representative of the U.S. health care system, both in geography and in the complexity of private and public health care payers and delivery networks. CONCLUSIONS Published studies of PCMH interventions often have similar broad elements, but precise components of care varied widely. The PCMH holds promise for improving the experiences of patients and staff, and potentially for improving care processes. However, current evidence is insufficient to determine effects on clinical and most economic outcomes. Ongoing studies identified through the horizon scan have potential to greatly expand the evidence base relating to PCMH. PMID:24422946
Maximizing Team Performance: The Critical Role of the Nurse Leader.
Manges, Kirstin; Scott-Cawiezell, Jill; Ward, Marcia M
2017-01-01
Facilitating team development is challenging, yet critical for ongoing improvement across healthcare settings. The purpose of this exemplary case study is to examine the role of nurse leaders in facilitating the development of a high-performing Change Team in implementing a patient safety initiative (TeamSTEPPs) using the Tuckman Model of Group Development as a guiding framework. The case study is the synthesis of 2.5 years of critical access hospital key informant interviews (n = 50). Critical juncture points related to team development and key nurse leader actions are analyzed, suggesting that nurse leaders are essential to maximize clinical teams' performance. © 2016 Wiley Periodicals, Inc.
Jones, A Kyle; Heintz, Philip; Geiser, William; Goldman, Lee; Jerjian, Khachig; Martin, Melissa; Peck, Donald; Pfeiffer, Douglas; Ranger, Nicole; Yorkston, John
2015-11-01
Quality control (QC) in medical imaging is an ongoing process and not just a series of infrequent evaluations of medical imaging equipment. The QC process involves designing and implementing a QC program, collecting and analyzing data, investigating results that are outside the acceptance levels for the QC program, and taking corrective action to bring these results back to an acceptable level. The QC process involves key personnel in the imaging department, including the radiologist, radiologic technologist, and the qualified medical physicist (QMP). The QMP performs detailed equipment evaluations and helps with oversight of the QC program, the radiologic technologist is responsible for the day-to-day operation of the QC program. The continued need for ongoing QC in digital radiography has been highlighted in the scientific literature. The charge of this task group was to recommend consistency tests designed to be performed by a medical physicist or a radiologic technologist under the direction of a medical physicist to identify problems with an imaging system that need further evaluation by a medical physicist, including a fault tree to define actions that need to be taken when certain fault conditions are identified. The focus of this final report is the ongoing QC process, including rejected image analysis, exposure analysis, and artifact identification. These QC tasks are vital for the optimal operation of a department performing digital radiography.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jones, A. Kyle, E-mail: kyle.jones@mdanderson.org; Geiser, William; Heintz, Philip
Quality control (QC) in medical imaging is an ongoing process and not just a series of infrequent evaluations of medical imaging equipment. The QC process involves designing and implementing a QC program, collecting and analyzing data, investigating results that are outside the acceptance levels for the QC program, and taking corrective action to bring these results back to an acceptable level. The QC process involves key personnel in the imaging department, including the radiologist, radiologic technologist, and the qualified medical physicist (QMP). The QMP performs detailed equipment evaluations and helps with oversight of the QC program, the radiologic technologist ismore » responsible for the day-to-day operation of the QC program. The continued need for ongoing QC in digital radiography has been highlighted in the scientific literature. The charge of this task group was to recommend consistency tests designed to be performed by a medical physicist or a radiologic technologist under the direction of a medical physicist to identify problems with an imaging system that need further evaluation by a medical physicist, including a fault tree to define actions that need to be taken when certain fault conditions are identified. The focus of this final report is the ongoing QC process, including rejected image analysis, exposure analysis, and artifact identification. These QC tasks are vital for the optimal operation of a department performing digital radiography.« less
Final report on CCM key comparison CCM.D-K2: Comparison of liquid density standards
NASA Astrophysics Data System (ADS)
Bettin, Horst; Jacques, Claude; Zelenka, Zoltán; Fujii, Ken-ichi; Kuramoto, Naoki; Chang, Kyung-Ho; Lee, Yong Jae; Becerra, Luis Omar; Domostroeva, Natalia
2013-01-01
The results are presented of the key comparison CCM.D-K2 that covered the density measurements of four liquids: the density of water at 20 °C, of pentadecane at 15 °C, 20 °C, 40 °C and 60°C, of tetrachloroethlyene at 5 °C and 20 °C and of a viscous oil at 20 °C. Seven national metrology institutes measured the densities at atmospheric pressure by hydrostatic weighing of solid density standards in the time interval from 27 April 2004 to 28 June 2004. Since the participants were asked not to include components for a possible drift or inhomogeneity of the liquid in their uncertainty budget, these uncertainty contributions are investigated for the final evaluation of the data. For this purpose, results of stability and homogeneity measurements of the pilot laboratory are used. The participants decided not to include a possible drift of the liquid's density since no significant drift could be detected, and the influence of the drift and its uncertainty are negligible. Similarly, the inhomogeneity of the water and pentadecane samples is not significant and has no influence on the evaluation. Thus, it was neglected. Only the inhomogeneities of tetrachloroethylene and of the viscous oil were significant. Consequently, they were included in the evaluation. With one or two exceptions, the results show good agreement among the participants. Only in the case of water are the results clearly discrepant. The key comparison reference values were calculated by the weighted mean (taking into account a small correlation between two participants) in the case of consistent results. Otherwise the Procedure B of Cox was used. The expanded uncertainties of all reference densities are below 1 × 10-5 in relative terms. This satisfies the needs of all customers who wish to calibrate or check liquid density measuring instruments such as oscillation-type density meters. The comparison fully supports the calibration measurement capabilities table in the BIPM key comparison database. The results can be used to link regional comparisons to this CCM key comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Developing a Process for Sustained Climate Assessment in the US Southwest Region
NASA Astrophysics Data System (ADS)
Duncan, B.; Rick, U. K.; McNie, E. C.
2017-12-01
Climate information needs often vary across states, regions, and sectors. While a national assessment provides foundational guidance about the science and impacts of climate change, there is also value in an ongoing climate assessment process with a more targeted regional geographic scale and sectoral focus. Such a process could provide timely and relevant climate information that is sometimes more detailed than what can be included in a national assessment, while also providing a foundation of knowledge and relationships that can be drawn on in larger-scale assessment processes. In the Sustained Climate Assessment in the Southwest project, researchers are investigating opportunities for sustained assessment in the US Southwest National Climate Assessment (NCA) region - an area that consists of Arizona, California, Colorado, Nevada, New Mexico, and Utah. This work is focused on identifying key elements of an ongoing climate assessment process for the region in collaboration with climate service providers and users, with the goal of connecting providers and users to increase access to information and understanding of climate impacts in decision-making contexts. It is focused on four key sectors that represent a range of existing capacity in the region: water, oceans and coasts, agriculture, and transportation. Recommendations for an ongoing assessment process may vary by sector - a reflection of the capacity and opportunity associated with each. In this presentation, we will share case studies of particularly useful or successful existing assessment activities and identify common characteristics across the case studies. We will also share preliminary recommendations for a regional sustained climate assessment process that draws on the broad existing capacity for climate assessment in the region and complements national-scale assessment processes.
Neural Oscillations Carry Speech Rhythm through to Comprehension
Peelle, Jonathan E.; Davis, Matthew H.
2012-01-01
A key feature of speech is the quasi-regular rhythmic information contained in its slow amplitude modulations. In this article we review the information conveyed by speech rhythm, and the role of ongoing brain oscillations in listeners’ processing of this content. Our starting point is the fact that speech is inherently temporal, and that rhythmic information conveyed by the amplitude envelope contains important markers for place and manner of articulation, segmental information, and speech rate. Behavioral studies demonstrate that amplitude envelope information is relied upon by listeners and plays a key role in speech intelligibility. Extending behavioral findings, data from neuroimaging – particularly electroencephalography (EEG) and magnetoencephalography (MEG) – point to phase locking by ongoing cortical oscillations to low-frequency information (~4–8 Hz) in the speech envelope. This phase modulation effectively encodes a prediction of when important events (such as stressed syllables) are likely to occur, and acts to increase sensitivity to these relevant acoustic cues. We suggest a framework through which such neural entrainment to speech rhythm can explain effects of speech rate on word and segment perception (i.e., that the perception of phonemes and words in connected speech is influenced by preceding speech rate). Neuroanatomically, acoustic amplitude modulations are processed largely bilaterally in auditory cortex, with intelligible speech resulting in differential recruitment of left-hemisphere regions. Notable among these is lateral anterior temporal cortex, which we propose functions in a domain-general fashion to support ongoing memory and integration of meaningful input. Together, the reviewed evidence suggests that low-frequency oscillations in the acoustic speech signal form the foundation of a rhythmic hierarchy supporting spoken language, mirrored by phase-locked oscillations in the human brain. PMID:22973251
NASA Astrophysics Data System (ADS)
Konopelko, L. A.; Efremova, O. V.; Fatina, O. V.; Orshanskaia, A. A.; Rozhnov, M. S.; Melnyk, D. M.; Petryshyn, P. V.
2016-01-01
The relevance of the COOMET.QM-K93 comparison is founded on paying particular attention to reliability of measurements which are performed during the medical examination of drivers of vehicles in order to assess the degree of alcoholic intoxication. Standard gas mixtures of ethanol in nitrogen in cylinders under pressure play a key role in providing metrological assurance of breath-alcohol analyzers. Participating laboratories: VNIIM and Ukrmetrteststandart. This comparison was carried out in 2014-2015. This supplementary comparison supports CMC claims for: ethanol in the range 50-500 μmol/mol in a matrix of either nitrogen or synthetic air. Results: The results are consistent with the reference values. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Meyer, C.; Solano, A.
2016-01-01
A Regional Metrology Organization (RMO) Key Comparison of dew/frost point temperatures was carried out by the National Institute of Standards and Technology (NIST, USA) and the Laboratorio Costarricense de Metrología (LACOMET, Costa Rica) between February 2015 and August 2015. The results of this comparison are reported here, along with descriptions of the humidity laboratory standards for NIST and LACOMET and the uncertainty budget for these standards. This report also describes the protocol for the comparison and presents the data acquired. The results are analyzed, determining degree of equivalence between the dew/frost-point standards of NIST and LACOMET. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Huang, P. H.; Meyer, C. W.; Martines-López, E.; Dávila Pacheco, J. A.; Méndez-Lango, E.
2014-01-01
A Regional Metrology Organization (RMO) Key Comparison of dew/frost point temperatures was carried out by the National Institute of Standards and Technology (NIST, USA) and the Centro Nacional de Metrologia (CENAM, Mexico) between July 2008 and December 2008. The results of this comparison are reported here, along with descriptions of the humidity laboratory standards for NIST and CENAM and the uncertainty budget for these standards. This report also describes the protocol for the comparison and presents the data acquired. The results are analyzed, determining degree of equivalence between the dew/frost-point standards of NIST and CENAM. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Huang, Peter; Meyer, Christopher; Brionizio, Julio D.
2015-01-01
A Regional Metrology Organization (RMO) Key Comparison of dew/frost point temperatures was carried out by the National Institute of Standards and Technology (NIST, USA) and the Instituto Nacional de Metrologia, Qualidade e Tecnologia (INMETRO, Brazil) between October 2009 and March 2010. The results of this comparison are reported here, along with descriptions of the humidity laboratory standards for NIST and INMETRO and the uncertainty budget for these standards. This report also describes the protocol for the comparison and presents the data acquired. The results are analyzed, determining degree of equivalence between the dew/frost-point standards of NIST and INMETRO. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Balancing intellectual monopoly privileges and the need for essential medicines
Martin, Greg; Sorenson, Corinna; Faunce, Thomas
2007-01-01
This issue of Globalization and Health presents a paper by Kerry and Lee that considers the TRIPS agreement and the recent policy debate regarding the protection of public health interest, particularly as they pertain to the Doha Declaration. In this editorial, we consider the debate, the conclusions thereof, and identify five questions that should be considered by key stakeholders in ongoing discussions. PMID:17565684
ERIC Educational Resources Information Center
Meckstroth, Alicia; Burwick, Andrew; Ponza, Michael; Marsh, Shawn; Novak, Tim; Phillips, Shannon; Diaz-Tena, Nuria; Ng, Judy
2006-01-01
Helping low-income families in rural areas find gainful employment and achieve economic self-sufficiency is an ongoing policy concern. The Rural Welfare-to-Work Strategies demonstration is using rigorous experimental designs to build knowledge about how to help low-income families in rural areas strive toward sustained employment and…
The manager's role in marketing. The Health Care Group.
1991-06-01
With the impending reductions in physician reimbursements, the key to a practice's ongoing vitality will be its ability to increase volume and gain greater market share. Traditionally, most doctors have relied on word-of-mouth referrals from current patients and physicians to bring in new patients. In today's health care environment, however, this approach to practice building is not enough to assure growth.
ERIC Educational Resources Information Center
FitzPatrick, Thaddeus
2012-01-01
Technology has changed the way that we live our lives. Interaction across continents has become a forefront of everyday engagement. With ongoing enhancements of technology, people are now able to communicate and learn in a virtual environment similar to that of the real world interaction. These improvements are shared in the field of education,…
2015-01-01
A brief overview of biorepository sustainability from the perspective of a federated biorepository system at the University of Iowa Carver College of Medicine is presented. The ongoing evolution of the federation and the efforts to improve efficacy and efficiency are described. The key sustainability factors identified are adaptability, focus, collaboration/networking, and service improvement. PMID:26697912
Nursing patients with epilepsy in secondary care settings.
Welsh, Rebecca; Kerley, Sarah
This article gives a brief overview of epilepsy and how a diagnosis is made. It highlights the importance of good observation and communication in its ongoing management. Long-term management of the condition and the acute management of seizures are considered. The article emphasises the effect on the individual, family and carers, identifies the key legislation and highlights the crucial role of secondary care nurses.
From Insurgency to Stability. Volume 1: Key Capabilities and Practices
2011-01-01
newly arrived personnel to understand the status of ongoing projects and whether individual contractors are performing to the contract...identifying where project funds are expended wastefully and where performance is substandard). That said, while an improved system to monitor...been disappoint- ing. Experiences there have shown that “capacity - building ” in the jus- tice sector does not necessarily produce better performance
The Proposed Anti-Counterfeiting Trade Agreement: Background and Key Issues
2010-03-12
or is negotiating regional and bilateral FTAs with several of the ACTA participants. Some observers have questioned why countries designated in...Notably, China, India , and Brazil currently are not participants to this agreement. Negotiations on the agreement are ongoing; participants have expressed...bilateral free trade agreements ( FTAs ). In negotiating recent FTAs , the USTR frequently has sought levels of protection that exceed the minimum standards
ERIC Educational Resources Information Center
Powell, Justin J. W.; Dusdal, Jennifer
2017-01-01
Charting significant growth in science production over the 20th century in four European Union member states, this neo-institutional analysis describes the development and current state of universities and research institutes that bolster Europe's position as a key region in global science. On-going internationalization and Europeanization of…
ERIC Educational Resources Information Center
Rubin, Allen
2015-01-01
This keynote address discusses previous and ongoing efforts to reduce the persistent gap between research and practice in social work and offers recommendations for further bridging that gap. Key among those recommendations is the need to conduct descriptive outcome studies of efforts to adapt research-supported interventions in everyday practice…
ERIC Educational Resources Information Center
Neal, Mark; Finlay, Jim; Karkoulian, Silva; Catana, Doina; Pellegrino, Robert
2015-01-01
When seeking to understand corruption in its ongoing temporal context, it is useful to consider business students. Because of their high numbers and the kinds of jobs they enter, they have a key role to play in challenging or sustaining corruption in their societies. This exploratory study focuses on these people in three countries in different…
Galbraith, Joseph W
2015-12-01
A brief overview of biorepository sustainability from the perspective of a federated biorepository system at the University of Iowa Carver College of Medicine is presented. The ongoing evolution of the federation and the efforts to improve efficacy and efficiency are described. The key sustainability factors identified are adaptability, focus, collaboration/networking, and service improvement.
Individual Quality of Life: Can It Be Accounted for by Psychological or Subjective Well-Being?
ERIC Educational Resources Information Center
Ring, L.; Hofer, S.; McGee, H.; Hickey, A.; O'Boyle, C. A.
2007-01-01
There is ongoing discussion in the scientific literature about the need for a more theoretical foundation to underpin quality of life (QoL) measurement. This paper applied Keyes et al.'s ["J. Pers. Soc. Psychol." 82 (2002) 1007] model of well-being as a framework to assess whether respondents (n = 136 students) focus on elements of subjective…
ERIC Educational Resources Information Center
Kos Kecojevic, Živa; Gaber, Slavko
2012-01-01
In the article, we present the conceptualisation and selected results of ongoing research dealing with the particular area of top decision making in education in Central and South East Europe. Aiming at a Bourdieuian type of objectification of key agents of decision making in education--ministers--a group of researchers from the region is in the…
USDA-ARS?s Scientific Manuscript database
More than half a million specimens of wild-caught Lepidoptera caterpillars have been reared for their parasitoids, identification, and DNA barcoding over a period of 34 years (and ongoing) from Area de Conservación de Guanacaste (ACG), northwestern Costa Rica. This provides the world’s best place-ba...
ERIC Educational Resources Information Center
Boak, George; Watt, Peter; Gold, Jeff; Devins, David; Garvey, Robert
2016-01-01
This paper contributes to an understanding of the processes by which organisational actors learn how to affect positive and sustainable social change in their local region through action learning, action research and appreciative inquiry. The paper is based on a critically reflective account of key findings from an ongoing action research project,…
NASA Astrophysics Data System (ADS)
Bettin, Horst; Heinonen, Martti; Gosset, André; Zelenka, Zoltán; Lorefice, Salvatore; Hellerud, Kristen; Durlik, Hanna; Jordaan, Werner; Field, Ireen
2016-01-01
The results of the key comparison EUROMET 627 (EUROMET.M.D-K2) are presented. This project covered the density measurements of three liquids: dodecane, water and an oil of high viscosity measured at 15 °C, 20 °C and 40 °C. Seven European metrology laboratories and the South African laboratory CSIR-NML (now: NMISA) measured the densities at atmospheric pressure by hydrostatic weighing of solid density standards between 04 October 2001 and 18 December 2001. The stability and homogeneity of the liquids were investigated by the pilot laboratory PTB. The results generally show good agreement among the participants. Only for the simple Mohr-Westphal balances do the uncertainties seem to be underestimated by the laboratories. Furthermore, the measurement of high-viscosity oil was difficult for some laboratories. Nevertheless, the five laboratories PTB/DE, BNM/FR (now: LNE/FR), OMH/HU (now: MKEH/HU), IMGC/IT (now: INRIM/IT) and GUM/PL agree with each other for stated uncertainties of 0.05 kg/m3 or less. This satisfies the current needs of customers who wish to calibrate or check liquid density measuring instruments such as oscillation-type density meters. No reference values were calculated since the subsequent CCM key comparison CCM.D-K2 had a different scope and the EUROMET 627 comparison was soon superseded by the EURAMET 1019 (EURAMET.M.D-K2) comparison. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
International comparison of AC-DC current transfer standards
NASA Astrophysics Data System (ADS)
Heine, G.; Garcocz, M.; Waldmann, W.
2017-01-01
The measurements of the international comparison of ac-dc current transfer standards identified as EURAMET.EM-K12 started in June 2012 and were completed in December 2014. Twenty NMIs in the EURAMET region and one NMI in the AFRIMET region took part: BEV (Austria), CMI (Czech Republic), PTB (Germany), METAS (Switzerland), JV (Norway), UME (Turkey), GUM (Poland), IPQ (Portugal), CEM (Spain), INRIM (Italy), SP (Sweden), DANIAmet-MI-Trescal (Denmark), BIM (Bulgaria), MKEH (Hungary), SIQ (Slovenia), LNE (France), NSAI NML (Ireland), VSL (The Netherlands), NPL (United Kingdom), Metrosert (Estonia), NIS (Egypt). The comparison was proposed to link the National Metrology Institutes organised in EURAMET to the key comparison CCEM-K12. The ac-dc current transfer difference of each travelling standard had been measured at its nominal current 10 mA and 5 A at the following frequencies: 10 Hz, 55 Hz, 1 kHz, 10 kHz, 20 kHz, 50 kHz, 100 kHz. The test points were selected to link the results with the equivalent CCEM Key Comparison (CCEM-K12), through five NMIs participating in both EURAMET and CCEM key comparisons (PTB, JV, NPL, SP and BEV). The report shows the degree of equivalence in the EURAMET region and also the degree of equivalence with the corresponding CCEM reference value. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Dey, Mahua; Stadnik, Agnieszka; Riad, Fady; Zhang, Lingjiao; McBee, Nichol; Kase, Carlos; Carhuapoma, J Ricardo; Ram, Malathi; Lane, Karen; Ostapkovich, Noeleen; Aldrich, Francois; Aldrich, Charlene; Jallo, Jack; Butcher, Ken; Snider, Ryan; Hanley, Daniel; Ziai, Wendy; Awad, Issam A
2015-03-01
Retrospective series report varied rates of bleeding and infection with external ventricular drainage (EVD). There have been no prospective studies of these risks with systematic surveillance, threshold definitions, or independent adjudication. To analyze the rate of complications in the ongoing Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III (CLEAR III) trial, providing a comparison with a systematic review of complications of EVD in the literature. Patients were prospectively enrolled in the CLEAR III trial after placement of an EVD for obstructive intraventricular hemorrhage and randomized to receive recombinant tissue-type plasminogen activator or placebo. We counted any detected new hemorrhage (catheter tract hemorrhage or any other distant hemorrhage) on computed tomography scan within 30 days from the randomization. Meta-analysis of published series of EVD placement was compiled with STATA software. Growing or unstable hemorrhage was reported as a cause of exclusion from the trial in 74 of 5707 cases (1.3%) screened for CLEAR III. The first 250 patients enrolled have completed adjudication of adverse events. Forty-two subjects (16.8%) experienced ≥1 new bleeds or expansions, and 6 of 250 subjects (2.4%) suffered symptomatic hemorrhages. Eleven cases (4.4%) had culture-proven bacterial meningitis or ventriculitis. Risks of bleeding and infection in the ongoing CLEAR III trial are comparable to those previously reported in EVD case series. In the present study, rates of new bleeds and bacterial meningitis/ventriculitis are very low despite multiple daily injections, blood in the ventricles, the use of thrombolysis in half the cases, and generalization to >60 trial sites.
Meyer, C W; Hill, K D
A Regional Metrology Organization (RMO) Key Comparison of dew/frost point temperatures was carried out by the National Institute of Standards and Technology (NIST, USA) and the National Research Council (NRC, Canada) between December 2014 and April, 2015. The results of this comparison are reported here, along with descriptions of the humidity laboratory standards for NIST and NRC and the uncertainty budget for these standards. This report also describes the protocol for the comparison and presents the data acquired. The results are analyzed, determining degree of equivalence between the dew/frost-point standards of NIST and NRC.
Meyer, C.W.; Hill, K.D.
2015-01-01
A Regional Metrology Organization (RMO) Key Comparison of dew/frost point temperatures was carried out by the National Institute of Standards and Technology (NIST, USA) and the National Research Council (NRC, Canada) between December 2014 and April, 2015. The results of this comparison are reported here, along with descriptions of the humidity laboratory standards for NIST and NRC and the uncertainty budget for these standards. This report also describes the protocol for the comparison and presents the data acquired. The results are analyzed, determining degree of equivalence between the dew/frost-point standards of NIST and NRC. PMID:26663952
ERIC Educational Resources Information Center
George, Magnus; Gordon, Ian; Hamilton, Eleanor
2010-01-01
The teaching of entrepreneurship as an academic subject, as opposed to the apprenticeship route, is the subject of ongoing debate. The authors suggest that there is a middle road and that, by integrating the business world into teaching in a significant way, the best of both approaches can be achieved. In a similar vein, the credibility of some…
Waging the War on Clinical Grade Inflation: The Ongoing Quest.
Seldomridge, Lisa A; Walsh, Catherine M
This study examined the presence of grade inflation in clinical courses 9 years after implementing strategies to improve grading precision. A comparison of clinical grades for cohort I (1997-2002) with cohort II (2009-2016) showed statistically lower grades in 2 courses (Adult 1 and Maternity) for cohort II. Suggestions for changing the way clinical experiences are planned, executed, and evaluated are provided.
Comparison Groups in Short Interrupted Time-Series: An Illustration Evaluating No Child Left Behind
ERIC Educational Resources Information Center
Wong, Manyee; Cook, Thomas D.; Steiner, Peter M.
2009-01-01
Interrupted time-series (ITS) are often used to assess the causal effect of a planned or even unplanned shock introduced into an on-going process. The pre-intervention slope is supposed to index the causal counterfactual, and deviations from it in mean, slope or variance are used to indicate an effect. However, a secure causal inference is only…
The Home Independence Program with non-health professionals as care managers: an evaluation.
Lewin, Gill; Concanen, Karyn; Youens, David
2016-01-01
The Home Independence Program (HIP), an Australian restorative home care/reablement service for older adults, has been shown to be effective in reducing functional dependency and increasing functional mobility, confidence in everyday activities, and quality of life. These gains were found to translate into a reduced need for ongoing care services and reduced health and aged care costs over time. Despite these positive outcomes, few Australian home care agencies have adopted the service model - a key reason being that few Australian providers employ health professionals, who act as care managers under the HIP service model. A call for proposals from Health Workforce Australia for projects to expand the scope of practice of health/aged care staff then provided the opportunity to develop, implement, and evaluate a service delivery model, in which nonprofessionals replaced the health professionals as Care Managers in the HIP service. Seventy older people who received the HIP Coordinator (HIPC) service participated in the outcomes evaluation. On a range of personal outcome measures, the group showed statistically significant improvement at 3 and 12 months compared to baseline. On each outcome, the improvement observed was larger than that observed in a previous trial in which the service was delivered by health professionals. However, differences in the timing of data collection between the two studies mean that a direct comparison cannot be made. Clients in both studies showed a similarly reduced need for ongoing home care services at both follow-up points. The outcomes achieved by HIPC, with non-health professionals as Care Managers, were positive and can be considered to compare favorably with the outcomes achieved in HIP when health professionals take the Care Manager role. These findings will be of interest to managers of home care services and to policy makers interested in reducing the long-term care needs of older community dwelling individuals.
NASA Astrophysics Data System (ADS)
Michotte, C.; Courte, S.; Ratel, G.; Kossert, K.; Nähle, O. J.
2009-01-01
In 2009, the Physikalisch-Technische Bundesanstalt (PTB), Germany, submitted a sample of known activity of 64Cu to the International Reference System (SIR) for activity comparison at the Bureau International des Poids et Mesures (BIPM). The value of the activity submitted was about 9.3 MBq. The result of this new comparison has been approved for publication by Section II of the Consultative Committee for Ionizing Radiation (CCRI(II)), comparison identifier BIPM.RI(II)-K1.Cu-64. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI Section II, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Qiao, Sun; Lifeng, Yang; Bartoli, Claire; Veldman, Ian; Ripper, Gustavo P.; Bruns, Thomas; Rask Licht, Torben; Kolasa, Joanna; Hof, Christian; Silva Pineda, Guillermo; Dickinson, Laurence; Ota, Akihiro; Cheung, Wan Sup; Yankovsky, Alexander; Shan, Cui
2017-01-01
This is the final report for CIPM key comparison CCAUV.V-K3 in the area of 'vibration' (quantity of acceleration). The aim of this comparison was to measure the voltage sensitivity of one accelerometer standard set with primary means at 27 frequencies from 0.1 Hz to 40 Hz. Fourteen Metrology Institutes from five RMOs have participated in the comparison with National Institute of Metrology, P.R. China as pilot lab and Laboratoire National de Métrologie et d'Essais and National Metrology Institute of South Africa as co-pilot labs. One quartz-flexure servo accelerometer of single-ended type and a signal conditioner was circulated among the participants. All but one of the participating laboratories provided their calibration results, which were mostly consistent within their declared expanded uncertainties for magnitude results. Only two participants failed to contribute to the KCRV values calculated for five frequencies. For phase shift, three participants could not contribute to the calculation of the KCRV values in a total of sixteen frequencies. This first low-frequency vibration key comparison revealed the current calibration capabilities of the fourteen participants of five RMOs. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCAUV, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
KEY COMPARISON: Final report on international key comparison CCQM-K53: Oxygen in nitrogen
NASA Astrophysics Data System (ADS)
Lee, Jeongsoon; Bok Lee, Jin; Moon, Dong Min; Seog Kim, Jin; van der Veen, Adriaan M. H.; Besley, Laurie; Heine, Hans-Joachim; Martin, Belén; Konopelko, L. A.; Kato, Kenji; Shimosaka, Takuya; Perez Castorena, Alejandro; Macé, Tatiana; Milton, Martin J. T.; Kelley, Mike; Guenther, Franklin; Botha, Angelique
2010-01-01
Gravimetry is used as the primary method for the preparation of primary standard gas mixtures in most national metrology institutes, and it requires the combined abilities of purity assessment, weighing technique and analytical skills. At the CCQM GAWG meeting in October 2005, it was agreed that KRISS should coordinate a key comparison, CCQM-K53, on the gravimetric preparation of gas, at a level of 100 µmol/mol of oxygen in nitrogen. KRISS compared the gravimetric value of each cylinder with an analytical instrument. A preparation for oxygen gas standard mixture requires particular care to be accurate, because oxygen is a major component of the atmosphere. Key issues for this comparison are related to (1) the gravimetric technique which needs at least two steps for dilution, (2) oxygen impurity in nitrogen, and (3) argon impurity in nitrogen. The key comparison reference value is obtained from the linear regression line (with origin) of a selected set of participants. The KCRV subset, except one, agree with each other. The standard deviation of the x-residuals of this group (which consists of NMIJ, VSL, NIST, NPL, BAM, KRISS and CENAM) is 0.056 µmol/mol and consistent with the uncertainties given to their standard mixtures. The standard deviation of the residuals of all participating laboratory is 0.182 µmol/mol. With respect to impurity analysis, overall argon amounts of the cylinders are in the region of about 3 µmol/mol however; four cylinders showed an argon amount fraction over 10 µmol/mol. Two of these are inconsistent with the KCRV subset. The explicit separation between two peaks of oxygen and argon in the GC chromatogram is essential to maintain analytical capability. Additionally oxygen impurity analysis in nitrogen is indispensable to ensure the preparative capability. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
Reinventing the Wheel: One Program's Approach to Redesign of Didactic Courses.
Hudak, Nicholas M; Scott, Victoria; Spear, Sherrie B; Hills, Karen J
2015-12-01
Curriculum and course redesign are expected and intentional efforts in health professions education. For physician assistant (PA) education, ongoing program self-assessment is a required accreditation standard and may guide deliberate changes within curriculum. The purpose of this article is to describe one PA program’s approach to the redesign of 4 courses into 3 courses that span the entire didactic phase. Significant lessons learned include the importance of planning ahead, identifying key players, documenting the process as part of ongoing self-assessment, competency mapping, and being prepared to make real-time modifications and changes based on course evaluations and faculty feedback. Our approach and guiding principles to the successful redesign of the didactic courses may provide both established and new PA educational programs with useful methods to apply in their own unique curricula.
Environmental Health: Threats and their Interactions
Holdstock, Douglas
2008-01-01
Improvements in the provision of an acceptable standard of health care, particularly in the developing world, will be undermined by three ongoing processes: ongoing armed conflicts; the threat of global warming due to rising levels of greenhouse gases, particularly carbon dioxide emitted by developed countries; and by rapidly rising populations. The key features of these three threats are summarised, and it is shown that interactions between them increase both the likelihood of their occurrence and the probable harm that they will cause. Some of the interactions are described, with ways of providing health care taking into account the threats and their interactions, and the paradox is emphasised that better health care in the developing world will further increase population growth followed by increased greenhouse gas emissions. Improved education for women and free and unlimited access to modern methods of contraception are vital. PMID:21572838
Advanced SiC/SiC Ceramic Composites For Gas-Turbine Engine Components
NASA Technical Reports Server (NTRS)
Yun, H. M.; DiCarlo, J. A.; Easler, T. E.
2004-01-01
NASA Glenn Research Center (GRC) is developing a variety of advanced SiC/SiC ceramic composite (ASC) systems that allow these materials to operate for hundreds of hours under stress in air at temperatures approaching 2700 F. These SiC/SiC composite systems are lightweight (approximately 30% metal density) and, in comparison to monolithic ceramics and carbon fiber-reinforced ceramic composites, are able to reliably retain their structural properties for long times under aggressive gas-turbine engine environments. The key for the ASC systems is related first to the NASA development of the Sylramic-iBN Sic fiber, which displays higher thermal stability than any other SiC- based ceramic fibers and possesses an in-situ grown BN surface layer for higher environmental durability. This fiber is simply derived from Sylramic Sic fiber type that is currently produced at ATK COI Ceramics (COIC). Further capability is then derived by using chemical vapor infiltration (CVI) and/or polymer infiltration and pyrolysis (PIP) to form a Sic-based matrix with high creep and rupture resistance as well as high thermal conductivity. The objectives of this study were (1) to optimize the constituents and processing parameters for a Sylramic-iBN fiber reinforced ceramic composite system in which the Sic-based matrix is formed at COIC almost entirely by PIP (full PIP approach), (2) to evaluate the properties of this system in comparison to other 2700 F Sylramic-iBN systems in which the matrix is formed by full CVI and CVI + PIP, and (3) to examine the pros and cons of the full PIP approach for fabricating hot-section engine components. A key goal is the development of a composite system with low porosity, thereby providing high modulus, high matrix cracking strength, high interlaminar strength, and high thermal conductivity, a major property requirement for engine components that will experience high thermal gradients during service. Other key composite property goals are demonstration at high temperatures of high environmental resistance and high creep resistance, which in turn will result in long component life. Data are presented from a variety of laboratory tests on simple two-dimensional panels that examine these properties and compare the performance of the optimized full PIP system with those of the full CVI and CVI + PIP hybrid systems. Underlying mechanisms for performance differences in the various systems are discussed. Remaining issues for further property enhancement and for application of the full PIP approach for engine components are also discussed, as well as on-going approaches at NASA to solve these issues.
NASA Astrophysics Data System (ADS)
Kessler, C.; Burns, D.; Cardoso, J.
2018-01-01
A comparison of the standards for air kerma of the Instituto Superior Técnico, Laboratório de Proteção e Segurança Radiológica (IST-LPSR), Portugal and of the Bureau International des Poids et Mesures (BIPM) was carried out in the 60Co radiation beam of the BIPM in December 2015. The comparison result, evaluated as a ratio of the IST-LPSR and the BIPM standards for air kerma, is 1.0026 with a combined standard uncertainty of 1.7 × 10-3. The results for an indirect comparison made at the same time are consistent with the direct results at the level of 1.1 parts in 103. The results are analysed and presented in terms of degrees of equivalence, suitable for entry in the BIPM key comparison database. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Allisy-Roberts, P. J.; Kessler, C.; Burns, D. T.; Berlyand, V.; Berlyand, A.
2010-01-01
A new comparison of the standards for absorbed dose to water of the All-Russian Scientific Research Institute for Physical-Technical and Radiotechnical Measurements (VNIIFTRI), Russia and of the Bureau International des Poids et Mesures (BIPM) has been made in 60Co gamma radiation in 2009. The results show that the VNIIFTRI and the BIPM standards for absorbed dose to water are in agreement, yielding a mean ratio of 0.9976 for the calibration coefficients of the transfer chambers, the difference from unity being within the combined standard uncertainty (0.0043) for this result. This result is consistent with the earlier 2001 comparison result of 0.9967 (43). The updated degrees of equivalence for the VNIIFTRI are compared with those of the other national metrology institutes as presented in the BIPM key comparison database. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI Section I, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
van Boven, Job F. M.; Maguire, Terence; Goyal, Pankaj; Altman, Pablo
2016-01-01
The aim of this paper was to propose key steps for community pharmacist integration into a patient care pathway for chronic obstructive pulmonary disease (COPD) management. A literature search was conducted to identify publications focusing on the role of the community pharmacist in identification and management of COPD. The literature search highlighted evidence supporting an important role for pharmacists at each of the four key steps in the patient care pathway for COPD management. Step 1 (primary prevention): pharmacists are ideally placed to provide information on disease awareness and risk prevention campaigns, and to encourage lifestyle interventions, including smoking cessation. Step 2 (early detection/case finding): pharmacists are often the first point of contact between the patient and the healthcare system and can therefore play an important role in the early identification of patients with COPD. Step 3 (management and ongoing support): pharmacists can assist patients by providing advice and education on dosage, inhaler technique, treatment expectations and the importance of adherence, and by supporting self‐management, including recognition and treatment of COPD exacerbations. Step 4 (review and follow‐up): pharmacists can play an important role in monitoring adherence and ongoing inhaler technique in patients with COPD. In summary, pharmacists are ideally positioned to play a vital role in all key stages of an integrated COPD patient care pathway from early disease detection to the support of management plans, including advice and counselling regarding medications, inhaler technique and treatment adherence. Areas requiring additional consideration include pharmacist training, increasing awareness of the pharmacist role, administration and reimbursement, and increasing physician–pharmacist collaboration. PMID:27510273
The Impact of a Research Ethics Training Program: Romania as a Case Study.
Loue, Sana
2014-12-01
Case Western Reserve University's (CWRU) Training Program in International Research Ethics, funded by the Fogarty International Center, has been ongoing in Romania since 2000. The program consists of multiple components: a U.S.- based MA degree program for long-term trainees, Romania-based short courses, a U.S.-based opportunity for mid-and senior-level personnel to develop collaborative writing or research projects and present lectures, and a newsletter and various Internet-based activities. We evaluated the impact of the training program on bioethics in Romania through a survey of the training program's long-term trainees, a literature search for trainee publications, interviews with key informants, and identification of key events during the course of the program. Findings indicate that the program has had a considerable impact in the field of bioethics through trainee authorship of peer-reviewed publications, books, and chapters; trainee career trajectories that encompass activities related to research ethics; and the development of a Romania-based master's degree program in bioethics and a Center of Bioethics and Health Policy. We attribute these achievements to the establishment of strong relationships between CWRU in Cleveland and the University of Medicine and Pharmacy Gr. T. Popa in Iasi, Romania, prior to the initiation of the training program; collaboration with key Romania-based institutional partners that are equally invested in the program's success; reliance of the program on a solid theoretical framework; ongoing program responsiveness to trainee and country needs; and a sustained commitment of time, expertise, and funding by the funders, sponsors, and in-country collaborators.
The Impact of a Research Ethics Training Program: Romania as a Case Study
Loue, Sana
2017-01-01
Case Western Reserve University's (CWRU) Training Program in International Research Ethics, funded by the Fogarty International Center, has been ongoing in Romania since 2000. The program consists of multiple components: a U.S.-based MA degree program for long-term trainees, Romania-based short courses, a U.S.-based opportunity for mid-and senior-level personnel to develop collaborative writing or research projects and present lectures, and a newsletter and various Internet-based activities. We evaluated the impact of the training program on bioethics in Romania through a survey of the training program's long-term trainees, a literature search for trainee publications, interviews with key informants, and identification of key events during the course of the program. Findings indicate that the program has had a considerable impact in the field of bioethics through trainee authorship of peer-reviewed publications, books, and chapters; trainee career trajectories that encompass activities related to research ethics; and the development of a Romania-based master's degree program in bioethics and a Center of Bioethics and Health Policy. We attribute these achievements to the establishment of strong relationships between CWRU in Cleveland and the University of Medicine and Pharmacy Gr. T. Popa in Iasi, Romania, prior to the initiation of the training program; collaboration with key Romania-based institutional partners that are equally invested in the program's success; reliance of the program on a solid theoretical framework; ongoing program responsiveness to trainee and country needs; and a sustained commitment of time, expertise, and funding by the funders, sponsors, and in-country collaborators. PMID:26247075
ERIC Educational Resources Information Center
Lane, Brett; Souvanna, Phomdaen
2014-01-01
This College Success Research Brief is one of a series of briefs documenting the implementation and impact of Mass Insight's College Success/STEM program. The research briefs are intended to share key findings, highlight ongoing questions and lines of inquiry, and inform the thinking of practitioners and policymakers on how to scale up efforts to…
The NASA John C. Stennis Environmental Geographic Information System
NASA Technical Reports Server (NTRS)
Cohan, Tyrus
2002-01-01
Contents include the following: 1. Introduction: Background information. Initial applications of the SSC EGIS. Ongoing projects. 2.Scope of SSC EGIS. 3. Data layers. 4. Onsite operations. 5. Landcover classifications. 6. Current activities. 7. GIS/Key. 8. Infrastructure base map - development. 9. Infrastructure base map - application. 10. Incorrected layer. 11. Corrected layer. 12. Emergency environmental response tool. 13. Future directions. 14. Bridging the gaps. 15. Environmental geographical information system.
Final report on key comparison CCQM-K100: Analysis of copper in ethanol
NASA Astrophysics Data System (ADS)
Zhou, Tao; Kakoulides, Elias; Zhu, Yanbei; Jaehrling, Reinhard; Rienitz, Olaf; Saxby, David; Phukphatthanachai, Pranee; Yafa, Charun; Labarraque, Guillaume; Cankur, Oktay; Can, Süleyman Z.; Konopelko, Leonid A.; Kustikov, Yu A.; Caciano de Sena, Rodrigo; Marques Rodrigues, Janaina; Fonseca Sarmanho, Gabriel; Fortunato de Carvalho Rocha, Werickson; dos Reis, Lindomar Augusto
2014-01-01
The increase in renewable sources in the energy matrix of the countries is an effort to reduce dependency on crude oil and the environmental impacts associated with its use. In order to help overcome the lack of widely accepted quality standards for fuel ethanol and to guarantee its competitiveness in the international trade market, the NMIs have been working to develop certified reference materials for bio-fuels and measurement methods. Inorganic impurities such as Cu, Na and Fe may be present in the fuel ethanol and their presence is associated with corrosion and the formation of oxide deposits in some engine parts. The key comparison CCQM-K100 was carried out under the auspices of the Inorganic Analysis Working Group (IAWG) and the coordination of the National Institute of Metrology, Quality and Technology (INMETRO). The objective of this key comparison was to compare the measurement capabilities of the participants for the determination of Cu in fuel ethanol. Ten NMIs participated in this exercise and most of them used the isotopic dilution method for determining the amount of Cu. The median was chosen as key comparison reference value (KCRV). The assigned KCRV for the Cu content was 0.3589 µg/g with a combined standard uncertainty of 0.0014 µg/g. In general, there is a good agreement among the participants' results. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Comparisons between Intel 386 and i486 microprecessors
NASA Technical Reports Server (NTRS)
Liu, Yuan-Kwei
1989-01-01
A quick and preliminary comparison is made between the Intel 386 and i486 microprocessors. The following topics are discussed: the i486 key elements, comparison of instruction set architecture, the i486 on-chip cache characteristics, the i486 multiprocessor support, comparison of performance, comparison of power consumption, comparison of radiation hardening potential, and recommendations for the Space Station Freedom (SSF) Data Management System (DMS).
Zang, Aiping; Chen, Haiying; Dou, Xianying; Jin, Jing; Cai, Weiming
2013-01-01
Gravitropism is a complex process involving a series of physiological pathways. Despite ongoing research, gravitropism sensing and response mechanisms are not well understood. To identify the key transcripts and corresponding pathways in gravitropism, a whole-genome microarray approach was used to analyze transcript abundance in the shoot base of rice (Oryza sativa sp. japonica) at 0.5 h and 6 h after gravistimulation by horizontal reorientation. Between upper and lower flanks of the shoot base, 167 transcripts at 0.5 h and 1202 transcripts at 6 h were discovered to be significantly different in abundance by 2-fold. Among these transcripts, 48 were found to be changed both at 0.5 h and 6 h, while 119 transcripts were only changed at 0.5 h and 1154 transcripts were changed at 6 h in association with gravitropism. MapMan and PageMan analyses were used to identify transcripts significantly changed in abundance. The asymmetric regulation of transcripts related to phytohormones, signaling, RNA transcription, metabolism and cell wall-related categories between upper and lower flanks were demonstrated. Potential roles of the identified transcripts in gravitropism are discussed. Our results suggest that the induction of asymmetrical transcription, likely as a consequence of gravitropic reorientation, precedes gravitropic bending in the rice shoot base. PMID:24040303
NASA Astrophysics Data System (ADS)
Jalali, Maryam; Sheng, Jian
2016-11-01
This study used laboratory experiments to assess degradation of crude oil by physical and biological processes including dissolution and consumption. To perform this study, we have developed a bioassay that consists of a flow chamber with a bottom glass substrate printed with an array of pico-liter oil droplets using micro-Transfer Printing. The technique allows the printing of highly homogeneous pico-liter droplet array with different dimensions and shapes that can be maintained for weeks. Since the droplets are pinned and stationary on the bottom substrate, the key processes can be evaluated by measuring the change of shape and volume using Atomic Force Microscopy. Parallel microfluidic bioassays are established at the beginning, exposed to abiotic/biotic solutions, and scarified for characterization at given time intervals for each experiment. Two processes, dissolution and consumption, are investigated. In addition, the effects of dispersant on these processes are also studied. The results show that the amount of oil degraded by bacteria accounts for almost 50% of the total volume in comparison to 25% via dissolution. Although dispersant has a subtle effect on dissolution, the effect on rates of consumption and its asymptotic behavior are substantial. Experiments involving different bacterial strains, dispersant concentration, and flow shear rate are on-going.
High resolution pollutant measurements in complex urban ...
Measuring air pollution in real-time using an instrumented vehicle platform has been an emerging strategy to resolve air pollution trends at a very fine spatial scale (10s of meters). Achieving second-by-second data representative of urban air quality trends requires advanced instrumentation, such as a quantum cascade laser utilized to resolve carbon monoxide and real-time optical detection of black carbon. An equally challenging area of development is processing and visualization of complex geospatial air monitoring data to decipher key trends of interest. EPA’s Office of Research and Development staff have applied air monitoring to evaluate community air quality in a variety of environments, including assessing air quality surrounding rail yards, evaluating noise wall or tree stand effects on roadside and on-road air quality, and surveying of traffic-related exposure zones for comparison with land-use regression estimates. ORD has ongoing efforts to improve mobile monitoring data collection and interpretation, including instrumentation testing, evaluating the effect of post-processing algorithms on derived trends, and developing a web-based tool called Real-Time Geospatial Data Viewer (RETIGO) allowing for a simple plug-and-play of mobile monitoring data. Example findings from mobile data sets include an estimated 50% in roadside ultrafine particle levels when immediately downwind of a noise barrier, increases in neighborhood-wide black carbon levels (3
Döhnel, Katrin; Schuwerk, Tobias; Sodian, Beate; Hajak, Göran; Rupprecht, Rainer; Sommer, Monika
2017-12-01
False belief (FB) reasoning is a key Theory of Mind (ToM) competence. By 4 years of age, children understand that a person's behavior can be based on a FB about reality. Children cannot understand that a person's emotion can also be based on a FB before the age of six. In order to generate hypothesis on basic processes distinguishing these two types of belief reasoning, the present functional magnetic resonance imaging study in adults directly compares functional activity associated with these two FB tasks. Both tasks were associated with activity in the ToM network including the medial prefrontal cortex and the left temporo-parietal junction. Differential activity was observed in the anterior dorsolateral prefrontal cortex for FB-based emotion relative to behavior attribution. Contrary to FB behavior attribution, FB-based emotion attribution requires the processing of two different mental states: a belief and an emotion and their relation to each other. The activity pattern may reflect the differential demands on cognitive processes associated with the two different belief-based attribution processes. These results shed new light on the still ongoing debate about the nature of the developmental lag between the two FB tasks.
International Collaborations on Engineered Barrier Systems: Brief Overview of SKB-EBS Activities.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Jove-Colon, Carlos F.
2015-10-01
Research collaborations with international partners on the behavior and performance of engineered barrier systems (EBS) are an important aspect of the DOE-NE Used Fuel Disposition Campaign strategy in the evaluation of disposal design concepts. These international partnerships are a cost-effective way of engaging in key R&D activities with common goals resulting in effective scientific knowledge exchanges thus enhancing existing and future research programs in the USA. This report provides a brief description of the activities covered by the Swedish Nuclear Fuel and Waste Management Company (SKB) EBS Task Force (TF) (referred hereafter as SKB EBS TF) and potential future directionsmore » for engagement of the DOE-NE UFDC program in relevant R&D activities. Emphasis is given to SKB EBS TF activities that are still ongoing and aligned to the UFDC R&D program. This include utilization of data collected in the bentonite rock interaction experiment (BRIE) and data sets from benchmark experiments produced by the chemistry or “C” part of the SKB EBS TF. Potential applications of information generated by this program include comparisons/tests between model and data (e.g., reactive diffusion), development and implementation of coupled-process models (e.g., HM), and code/model benchmarking.« less
SPARC's Stratospheric Sulfur and its Role in Climate Activity (SSiRC)
NASA Technical Reports Server (NTRS)
Thomason, Larry
2015-01-01
The stratospheric aerosol layer is a key component in the climate system. It affects the radiative balance of the atmosphere directly through interactions with solar and terrestrial radiation, and indirectly through its effect on stratospheric ozone. Because the stratospheric aerosol layer is prescribed in many climate models and Chemistry-Climate Models (CCMs), model simulations of future atmospheric conditions and climate generally do not account for the interaction between the aerosol-sulfur cycle and changes in the climate system. The present understanding of how the stratospheric aerosol layer may be affected by future climate change and how the stratospheric aerosol layer may drive climate change is, therefore, very limited. The purposes of SSiRC (Stratospheric Sulfur and its Role in Climate) include: (i) providing a coordinating structure for the various individual activities already underway in different research centers; (ii) encouraging and supporting new instrumentation and measurements of sulfur containing compounds, such as COS, DMS, and non-volcanic SO2 in the UT/LS globally; and (iii) initiating new model/data inter-comparisons. SSiRC is developing collaborations with a number of other SPARC activities including CCMI and ACAM. This presentation will highlight the scientific goals of this project and on-going activities and propose potential interactions between SSiRC and ACAM.
Simulating the Risk of Liver Fluke Infection using a Mechanistic Hydro-epidemiological Model
NASA Astrophysics Data System (ADS)
Beltrame, Ludovica; Dunne, Toby; Rose, Hannah; Walker, Josephine; Morgan, Eric; Vickerman, Peter; Wagener, Thorsten
2016-04-01
Liver Fluke (Fasciola hepatica) is a common parasite found in livestock and responsible for considerable economic losses throughout the world. Risk of infection is strongly influenced by climatic and hydrological conditions, which characterise the host environment for parasite development and transmission. Despite on-going control efforts, increases in fluke outbreaks have been reported in recent years in the UK, and have been often attributed to climate change. Currently used fluke risk models are based on empirical relationships derived between historical climate and incidence data. However, hydro-climate conditions are becoming increasingly non-stationary due to climate change and direct anthropogenic impacts such as land use change, making empirical models unsuitable for simulating future risk. In this study we introduce a mechanistic hydro-epidemiological model for Liver Fluke, which explicitly simulates habitat suitability for disease development in space and time, representing the parasite life cycle in connection with key environmental conditions. The model is used to assess patterns of Liver Fluke risk for two catchments in the UK under current and potential future climate conditions. Comparisons are made with a widely used empirical model employing different datasets, including data from regional veterinary laboratories. Results suggest that mechanistic models can achieve adequate predictive ability and support adaptive fluke control strategies under climate change scenarios.
NASA Astrophysics Data System (ADS)
Matangulu Shrestha, Victor; Anandh, S.; Sindhu Nachiar, S.
2017-07-01
Concrete is a heterogeneous mixture constitute of cement as the main ingredient with a different mix of fine and coarse aggregate. The massive use of conventional concrete has a shortfall in its key ingredients, natural sand and coarse aggregate, due to increased industrialisation and globalisation. To overcome the shortage of material, an alternate material with similar mechanical properties and composition has to be studied, as replacement of conventional concrete. Coconut shell concrete is a prime option as replacement of key ingredients of conventional concrete as coconut is produced in massive quantity in south East Asia. Coconut shell concrete is lightweight concrete and different research is still ongoing concerning about its mix design and composition in the construction industry. Concrete is weak in tension as compared to compression, hence the fibre is used to refrain the crack in the concrete. Coconut fibre is one of many fibres which can be used in concrete. The main aim of this project is to analyse the use of natural by-products in the construction industry, make light weight concrete and eco-friendly construction. This project concerns with the comparison of the mechanical properties of coconut shell concrete and conventional concrete, replacing fine aggregate with quarry dust using coconut fibre. M25 grade of concrete was adopted and testing of concrete was done at the age of 3, 7 and 28 days. In this concrete mix, sand was replaced completely in volumetric measurement by quarry dust. The result was analysed and compared with addition of coconut fibre at varying percentage of 1%, 2%, 3%, 4% and 5%. From the test conducted, coconut shell concrete with quarry dust has the maximum value at 4% of coconut fibre while conventional concrete showed the maximum value at 2% of coconut fibre.
Leaks in the pipeline: separating demographic inertia from ongoing gender differences in academia.
Shaw, Allison K; Stanton, Daniel E
2012-09-22
Identification of the causes underlying the under-representation of women and minorities in academia is a source of ongoing concern and controversy. This is a critical issue in ensuring the openness and diversity of academia; yet differences in personal experiences and interpretations have mired it in controversy. We construct a simple model of the academic career that can be used to identify general trends, and separate the demographic effects of historical differences from ongoing biological or cultural gender differences. We apply the model to data on academics collected by the National Science Foundation (USA) over the past three decades, across all of science and engineering, and within six disciplines (agricultural and biological sciences, engineering, mathematics and computer sciences, physical sciences, psychology, and social sciences). We show that the hiring and retention of women in academia have been affected by both demographic inertia and gender differences, but that the relative influence of gender differences appears to be dwindling for most disciplines and career transitions. Our model enables us to identify the two key non-structural bottlenecks restricting female participation in academia: choice of undergraduate major and application to faculty positions. These transitions are those in greatest need of detailed study and policy development.
NASA Astrophysics Data System (ADS)
Huang, Xuebo
2009-01-01
In order to assess the performance of the standards and techniques used for calibration and measurement of UVA irradiance responsivity of photodetectors in NMISA, South Africa, a new comparison was decided as a follow-up to comparison APMP.PR-S1. It is registered in the Key Comparison Data Base (KCDB) of BIPM as a bilateral supplementary comparison, with the identifier APMP.PR-S1.1. The comparison was carried out following the same technical protocol as that of supplementary comparison APMP PR-S1. The principle, organization and method of the comparison, as well as the preliminary measurements at the pilot laboratory NMC-A*STAR Singapore, were described in the Final Report of the APMP.PR-S1 comparison. The results of this bilateral comparison show that the NMISA's results lie within ±2% against the comparison reference values of APMP.PR-S1, which is a great improvement. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the APMP, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Evans, David J.
2002-11-01
The documentary standards defining internationally adopted methodologies and protocols for calibrating transducers used to measure vibration are currently developed under the International Organization for Standardization (ISO) Technical Committee 108 Sub Committee 3 (Use and calibration of vibration and shock measuring instruments). Recent revisions of the documentary standards on primary methods for the calibration of accelerometers used to measure rectilinear motion have been completed. These standards can be, and have been, used as references in the technical protocols of key international and regional comparisons between National Measurement Institutes (NMIs) on the calibration of accelerometers. These key comparisons are occurring in part as a result of the creation of the Mutual Recognition Arrangement between NMIs which has appendices that document the uncertainties, and the comparisons completed in support of the uncertainties, claimed by the National Laboratories that are signatories of the MRA. The measurements for the first international and the first Interamerican System of Metrology (SIM) regional key comparisons in vibration have been completed. These intercomparisons were promulgated via the relatively new Consultative Committee for Acoustics, Ultrasound and Vibration (CCAUV) of the International Committee for Weights and Measures (CIPM) and SIM Metrology Working Group (MWG) 9, respectively.
Usefulness of a KT Event to Address Practice and Policy Gaps Related to Integrated Care.
Jackson, Karen; Boakye, Omenaa; Wallace, Nicole
2016-02-01
There are limited evaluations of the impact of knowledge translation (KT) activities aimed at addressing practice and policy gaps. We report on the impact of an interactive, end-of-grant KT event. Although action items were developed and key stakeholder support attained, minimal follow-through had occurred three months after the KT event. Several organizational obstacles to transitioning knowledge into action were identified: leadership, program policies, infrastructure, changing priorities, workload and physician engagement. Key messages include: (1) ensure ongoing and facilitated networking opportunities, (2) invest in building implementation capacity, (3) target multi-level implementation activities and (4) focus further research on KT evaluation. Copyright © 2016 Longwoods Publishing.
Black, Michael; Moolhuijzen, Paula; Chapman, Brett; Barrero, Roberto; Howieson, John; Hungria, Mariangela; Bellgard, Matthew
2012-01-01
The symbiotic relationship between legumes and nitrogen fixing bacteria is critical for agriculture, as it may have profound impacts on lowering costs for farmers, on land sustainability, on soil quality, and on mitigation of greenhouse gas emissions. However, despite the importance of the symbioses to the global nitrogen cycling balance, very few rhizobial genomes have been sequenced so far, although there are some ongoing efforts in sequencing elite strains. In this study, the genomes of fourteen selected strains of the order Rhizobiales, all previously fully sequenced and annotated, were compared to assess differences between the strains and to investigate the feasibility of defining a core ‘symbiome’—the essential genes required by all rhizobia for nodulation and nitrogen fixation. Comparison of these whole genomes has revealed valuable information, such as several events of lateral gene transfer, particularly in the symbiotic plasmids and genomic islands that have contributed to a better understanding of the evolution of contrasting symbioses. Unique genes were also identified, as well as omissions of symbiotic genes that were expected to be found. Protein comparisons have also allowed the identification of a variety of similarities and differences in several groups of genes, including those involved in nodulation, nitrogen fixation, production of exopolysaccharides, Type I to Type VI secretion systems, among others, and identifying some key genes that could be related to host specificity and/or a better saprophytic ability. However, while several significant differences in the type and number of proteins were observed, the evidence presented suggests no simple core symbiome exists. A more abstract systems biology concept of nitrogen fixing symbiosis may be required. The results have also highlighted that comparative genomics represents a valuable tool for capturing specificities and generalities of each genome. PMID:24704847
APMP key comparison for the measurement of air kerma for 60Co (APMP.RI(I)-K1.1)
NASA Astrophysics Data System (ADS)
Webb, D. V.; Lee, J.-H.; Budiantari, C. T.; Laban, J.; Saito, N.; Srimanoroth, S.; Khaled, N. E.
2016-01-01
The results are reported for an APMP.R(I)-K1.1 comparison that extends the regional comparison of standards for air kerma APMP.R(I)-K1 to several laboratories unable to participate earlier. The comparison was conducted with the goal of supporting the relevant calibration and measurement capabilities (CMCs) planned for publication by the participant laboratories. The comparison was conducted by the pilot laboratory, the Australian Radiation Protection and Nuclear Safety (ARPANSA), Australia, supported by the Institute of Nuclear Energy Research (INER), Taiwan, in a modified ring-shaped arrangement from September 2009 to November 2010, in parallel with an APMP.R(I)-K4 comparison being piloted by the INER. The laboratories that took part in the comparison were the ARPANSA, the Centre of Technology of Radiation Safety and Metrology (PTKMR-BATAN), Indonesia, the Division of Radiation and Medical Devices (DMSC), Thailand, the INER, the National Centre for Radiation Science (NCRS), New Zealand, the National Institute for Standards (NIS), Egypt and the National Metrology Institute of Japan (NMIJ/AIST), Japan. The two primary laboratories, ARPANSA and NMIJ, were chosen as the linking laboratories. Three ionization chambers were used as transfer instruments to be calibrated in terms of air kerma in 60Co radiotherapy beams. The comparison result is based on the ratio between the air kerma calibration coefficients (NK) determined by the participants and the mean of the results of the linking laboratories. The mean comparison ratio was found to be within 0.5 % of the key comparison reference value KCRV. The largest deviation between any two comparison ratios for the three chambers in terms of air kerma was 2.0 %. An analysis of the participant uncertainty budgets enabled the calculation of degrees of equivalence (DoE) in terms of the deviations of the results and their associated uncertainties. As a result of this APMP comparison, the BIPM key comparison database (KCDB) should include three new entries since neither the PTKMR-BATAN nor the NCRS have yet been declared designated institutes and consequently their results cannot be entered. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
What Defines the "Kingdom" Fungi?
Richards, Thomas A; Leonard, Guy; Wideman, Jeremy G
2017-06-01
The application of environmental DNA techniques and increased genome sequencing of microbial diversity, combined with detailed study of cellular characters, has consistently led to the reexamination of our understanding of the tree of life. This has challenged many of the definitions of taxonomic groups, especially higher taxonomic ranks such as eukaryotic kingdoms. The Fungi is an example of a kingdom which, together with the features that define it and the taxa that are grouped within it, has been in a continual state of flux. In this article we aim to summarize multiple lines of data pertinent to understanding the early evolution and definition of the Fungi. These include ongoing cellular and genomic comparisons that, we will argue, have generally undermined all attempts to identify a synapomorphic trait that defines the Fungi. This article will also summarize ongoing work focusing on taxon discovery, combined with phylogenomic analysis, which has identified novel groups that lie proximate/adjacent to the fungal clade-wherever the boundary that defines the Fungi may be. Our hope is that, by summarizing these data in the form of a discussion, we can illustrate the ongoing efforts to understand what drove the evolutionary diversification of fungi.
NASA Technical Reports Server (NTRS)
Shore, S.N.; Genovali, K.; Wahlgren, G. M.
2013-01-01
We present some results of an ongoing study of the long-term spectroscopic variations of AG Dra, a prototypical eruptive symbiotic system. We discuss the effects of the environment and orbital modulation in this system and some of the physical processes revealed by a comparison with the nova outburst of the symbiotic-like recurrent nova V407 Cyg 2010.
ERIC Educational Resources Information Center
Price-Mohr, Ruth; Price, Colin
2017-01-01
A survey of primary schools in England found that girls outperform boys in English across all phases (Ofsted in Moving English forward. Ofsted, Manchester, 2012). The gender gap remains an on-going issue in England, especially for reading attainment. This paper presents evidence of gender differences in learning to read that emerged during the…
Ovayolu, Ali; Arslanbuğa, Cansev Yilmaz; Gun, Ismet; Devranoglu, Belgin; Ozdemir, Arman; Cakar, Sule Eren
2016-01-01
To determine whether semen and plasma presepsin values measured in men with normozoospermia and oligoasthenospermia undergoing invitro-fertilization would be helpful in predicting ongoing pregnancy and live birth. Group-I was defined as patients who had pregnancy after treatment and Group-II comprised those with no pregnancy. Semen and blood presepsin values were subsequently compared between the groups. Parametric comparisons were performed using Student's t-test, and non-parametric comparisons were conducted using the Mann-Whitney U test. There were 42 patients in Group-I and 72 in Group-II. In the context of successful pregnancy and live birth, semen presepsin values were statistically significantly higher in Group-I than in Group-II (p= 0.004 and p= 0.037, respectively). The most appropriate semen presepsin cut-off value for predicting both ongoing pregnancy and live birth was calculated as 199 pg/mL. Accordingly, their sensitivity was 64.5% to 59.3%, their specificity was 57.0% to 54.2%, and their positive predictive value was 37.0% to 29.6%, respectively; their negative predictive value was 80.4% in both instances. Semen presepsin values could be a new marker that may enable the prediction of successful pregnancy and/or live birth. Its negative predictive values are especially high.
Key comparison of liquid density standards
NASA Astrophysics Data System (ADS)
Buchner, Christian; Zelenka, Zoltan; Kajastie, Heikki; Madec, Tanguy; Wolf, Henning; Vámossy, Csilla; Lorefice, Salvatore; Garberg, Torgunn; Lenard, Elżbieta; Spohr, Isabel; Mares, Gabriela; Spurný, Robert; Lumbreras, Angel; Medina, Nieves; Y Akçadağ, Ümit; Perkin, Michael
2015-01-01
Hydrostatic density determination for liquids is mainly performed by laboratories to provide means for calibrating liquid density measuring instruments such as oscillation-type density meters. From 2002 to 2005 the CIPM key comparison CCM.D-K2 'comparison of liquid density standards' was carried out piloted by the PTB. The aim was to compare the results of the density determination by the participating laboratories to support entries to the CMC tables in this sub-field. To provide further laboratories the possibility to support their entries to the CMC tables at the meeting of the EUROMET Working Group on Density in 2007 this comparison was agreed on. BEV (Austria) organized the comparison supported by the PTB (Germany). For the comparison samples of pentadecane, water, tetrachloroethylene and of an oil of high viscosity were measured in the temperature range from 5 °C to 60 °C at atmospheric pressure by hydrostatic weighing. The measurements were completed in 2008. The reference values of the first reports based on the draft of the CCM.D-K2. After the official publication of the CCM.D-K2 the reference values were recalculated and the report was finalised in 2015. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Interconnection: A qualitative analysis of adjusting to living with renal cell carcinoma
LEAL, ISABEL; MILBURY, KATHRIN; ENGEBRETSON, JOAN; MATIN, SURENA; JONASCH, ERIC; TANNIR, NIZAR; WOOD, CHRISTOPHER G.; COHEN, LORENZO
2017-01-01
Objective Adjusting to cancer is an ongoing process, yet few studies explore this adjustment from a qualitative perspective. The aim of our qualitative study was to understand how patients construct their experience of adjusting to living with cancer. Method Qualitative analysis was conducted of written narratives collected from four separate writing sessions as part of a larger expressive writing clinical trial with renal cell carcinoma patients. Thematic analysis and constant comparison were employed to code the primary patterns in the data into themes until thematic saturation was reached at 37 participants. A social constructivist perspective informed data interpretation. Results Interconnection described the overarching theme underlying the process of adjusting to cancer and involved four interrelated themes: (1) discontinuity—feelings of disconnection and loss following diagnosis; (2) reorientation—to the reality of cancer psychologically and physically; (3) rebuilding—struggling through existential distress to reconnect; and (4) expansion—finding meaning in interconnections with others. Participants related a dialectical movement in which disruption and loss catalyzed an ongoing process of finding meaning. Significance of results Our findings suggest that adjusting to living with cancer is an ongoing, iterative, nonlinear process. The dynamic interactions between the different themes in this process describe the transformation of meaning as participants move through and revisit prior themes in response to fluctuating symptoms and medical news. It is important that clinicians recognize the dynamic and ongoing process of adjusting to cancer to support patients in addressing their unmet psychosocial needs throughout the changing illness trajectory. PMID:28262086
Modified natural cycle IVF and mild IVF: a 10 year Swedish experience.
Aanesen, Arthur; Nygren, Karl-Gösta; Nylund, Lars
2010-01-01
Modified natural cycle IVF (mnc-IVF) or mild IVF (m-IVF) was offered to selected patients between 1996 and 2007; 43 patients during 129 cycles were treated with mnc-IVF and 145 couples during 250 cycles were treated with m-IVF. Comparison with outcome from conventional IVF cycles during the same time period and in the same clinic was performed. Although 53.5 and 39.6% of started cycles respectively never reached embryo transfer, the ongoing pregnancy rates per embryo transfer were 26.7% for mnc-IVF and 27.2% for m-IVF. During the same time period, cancellation rate for conventional IVF was 13.7% and the ongoing pregnancy rate per embryo transfer was 34.3%. For patients > or =38years of age, the ongoing pregnancy rate per embryo transfer was 17.5% in the m-IVF group. None of the patients aged > or =38years in the mnc-IVF group achieved an ongoing pregnancy. For patients treated with conventional IVF, the > or =38years of age pregnancy rate per embryo transfer was 27.0%. Costs of medication for m-IVF and mnc-IVF were 96.3 and 97.5% less than for the least expensive conventional IVF cycle respectively. Pregnancy rates per embryo transfer are acceptable for these treatment modalities, the cost for medication is low, risks for complications are dramatically reduced, and the treatments may be more psychologically acceptable to the patients. Copyright (c) 2009 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.
Interconnection: A qualitative analysis of adjusting to living with renal cell carcinoma.
Leal, Isabel; Milbury, Kathrin; Engebretson, Joan; Matin, Surena; Jonasch, Eric; Tannir, Nizar; Wood, Christopher G; Cohen, Lorenzo
2018-04-01
ABSTRACTObjective:Adjusting to cancer is an ongoing process, yet few studies explore this adjustment from a qualitative perspective. The aim of our qualitative study was to understand how patients construct their experience of adjusting to living with cancer. Qualitative analysis was conducted of written narratives collected from four separate writing sessions as part of a larger expressive writing clinical trial with renal cell carcinoma patients. Thematic analysis and constant comparison were employed to code the primary patterns in the data into themes until thematic saturation was reached at 37 participants. A social constructivist perspective informed data interpretation. Interconnection described the overarching theme underlying the process of adjusting to cancer and involved four interrelated themes: (1) discontinuity-feelings of disconnection and loss following diagnosis; (2) reorientation-to the reality of cancer psychologically and physically; (3) rebuilding-struggling through existential distress to reconnect; and (4) expansion-finding meaning in interconnections with others. Participants related a dialectical movement in which disruption and loss catalyzed an ongoing process of finding meaning. Our findings suggest that adjusting to living with cancer is an ongoing, iterative, nonlinear process. The dynamic interactions between the different themes in this process describe the transformation of meaning as participants move through and revisit prior themes in response to fluctuating symptoms and medical news. It is important that clinicians recognize the dynamic and ongoing process of adjusting to cancer to support patients in addressing their unmet psychosocial needs throughout the changing illness trajectory.
NASA Astrophysics Data System (ADS)
Nour, S.; Karam, L. R.; Inn, K. G. W.
2012-01-01
In 2005, the CCRI decided that a comparison undertaken from 2002 to 2008 by the NIST (under the auspices of the Inter-America Metrology System [SIM]) in the development of a new biota (Ocean Shellfish) standard reference material (SRM) was sufficiently well constructed that it could be converted into a supplementary comparison under CCRI(II), with comparison identifier CCRI(II)-S3. This would enable the comparison to be used to support calibration and measurement capability (CMC) claims for radionuclide measurements in reference materials (specifically, animal-based organic materials). Previous comparisons of radionuclides have been of single or multiple nuclides in non-complex matrices and results of such could not be extended to support capabilities to measure the same nuclides in reference materials. The results of this comparison have been used to determine the certified reference value of the SRM. The key comparison working group (KCWG) of the CCRI(II) has approved this approach as a mechanism to link all the results to certified 'reference values' in lieu of the key comparison reference value (KCRV) of these specified radionuclides in this type of matrix (shellfish) so as to support CMCs of similar materials submitted by the present participants. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Hiring the right people and management of research staff.
Kang, Duck-Hee; Davis, Linda; Habermann, Barbara; Rice, Marti; Broome, Marion
2005-12-01
Research grant or project management requires substantial skills and experiences of the principal investigator and the investigative team. Hiring the right people for appropriate positions and ongoing staff training and management are critical keys to successful conduct of the research projects. Necessary activities include the clear identification of positions and qualifications, recruiting the best, and hiring, training, and retaining the right staff. Tips and strategies for problem solving during each step are included.
Automated Monitoring of Pipeline Rights-of-Way
NASA Technical Reports Server (NTRS)
Frost, Chard Ritchie
2010-01-01
NASA Ames Research Center and the Pipeline Research Council International, Inc. have partnered in the formation of a research program to identify and develop the key technologies required to enable automated detection of threats to gas and oil transmission and distribution pipelines. This presentation describes the Right-of-way Automated Monitoring (RAM) program and highlights research successes to date, continuing challenges to implementing the RAM objectives, and the program's ongoing work and plans.
Solving the mystery of the internal structure of casein micelles.
Ingham, B; Erlangga, G D; Smialowska, A; Kirby, N M; Wang, C; Matia-Merino, L; Haverkamp, R G; Carr, A J
2015-04-14
The interpretation of milk X-ray and neutron scattering data in relation to the internal structure of the casein micelle is an ongoing debate. We performed resonant X-ray scattering measurements on liquid milk and conclusively identified key scattering features, namely those corresponding to the size of and the distance between colloidal calcium phosphate particles. An X-ray scattering feature commonly assigned to the particle size is instead due to protein inhomogeneities.
Cybersecurity and medical devices: A practical guide for cardiac electrophysiologists
Kramer, Daniel B.; Foo Kune, Denis; Auto de Medeiros, Julio; Yan, Chen; Xu, Wenyuan; Crawford, Thomas; Fu, Kevin
2017-01-01
Abstract Medical devices increasingly depend on software. While this expands the ability of devices to perform key therapeutic and diagnostic functions, reliance on software inevitably causes exposure to hazards of security vulnerabilities. This article uses a recent high‐profile case example to outline a proactive approach to security awareness that incorporates a scientific, risk‐based analysis of security concerns that supports ongoing discussions with patients about their medical devices. PMID:28512774
An Integrated Science Glovebox for the Gateway Habitat
NASA Technical Reports Server (NTRS)
Calaway, M. J.; Evans, C. A.; Garrison, D. H.; Bell, M. S.
2018-01-01
Next generation habitats for deep space exploration of cislunar space, the Moon, and ultimately Mars will benefit from on-board glovebox capability. Such a glovebox facility will maintain sample integrity for a variety of scientific endeavors whether for life science, materials science, or astromaterials. Glovebox lessons learned from decades of astromaterials curation, ISS on-board sample handling, and robust analog missions provide key design and operational factors for inclusion in on-going habitat development.
International comparison CCQM-K113—noble gas mixture
NASA Astrophysics Data System (ADS)
Lim, Jeong Sik; Lee, Jinbok; Moon, Dongmin; Tshilongo, James; Qiao, Han; Shuguo, Hu; Tiqiang, Zhang; Kelley, Michael E.; Rhoderick, George C.; Konopelko, L. A.; Kolobova, A. V.; Vasserman, I. I.; Zavyalov, S. V.; Gromova, E. V.; Efremova, O. V.
2017-01-01
Noble gases are one of the key elements used in the various processes of the bulbs industry, automotive industry, space industry, lasers industry, display industry as well as the semiconductor industry. Considering continuous growth, the provision of a reliable standard is required for those industries to improve their productivity. In this report, a result of the key comparison, CCQM-K113: noble gas mixture, is presented. Nominal amount-of-substance fractions of argon, neon, krypton, and xenon in helium are 20, 10, 2, and 1 cmol/mol, respectively. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Low dose evaluation of the antiandrogen flutamide following a Mode of Action approach
DOE Office of Scientific and Technical Information (OSTI.GOV)
Sarrabay, A.; UniverSud, INSERM, UMR-996 “Inflammation, Chemokines and Immunopathology”, Châtenay-Malabry; Bayer SAS, 16, rue Jean Marie Leclair, 69009 Lyon
ABSTRACT: The dose–response characterization of endocrine mediated toxicity is an on-going debate which is controversial when exploring the nature of the dose–response curve and the effect at the low-end of the curve. To contribute to this debate we have assessed the effects of a wide range of dose levels of the antiandrogen flutamide (FLU) on 7-week male Wistar rats. FLU was administered by oral gavage at doses of 0, 0.001, 0.01, 0.1, 1 and 10 mg/kg/day for 28 days. To evaluate the reproducibility, the study was performed 3 times. The molecular initiating event (MIE; AR antagonism), the key events (LHmore » increase, Leydig cell proliferation and hyperplasia increases) and associated events involved in the mode of action (MOA) of FLU induced testicular toxicity were characterized to address the dose response concordance. Results showed no effects at low doses (< 0.1 mg/kg/day) for the different key events studied. The histopathological changes (Leydig cell hyperplasia) observed at 1 and 10 mg/kg/day were associated with an increase in steroidogenesis gene expression in the testis from 1 mg/kg/day, as well as an increase in testosterone blood level at 10 mg/kg/day. Each key event dose–response was in good concordance with the MOA of FLU on the testis. From the available results, only monotonic dose–response curves were observed for the MIE, the key events, associated events and in effects observed in other sex related tissues. All the results, so far, show that the reference endocrine disruptor FLU induces threshold effects in a standard 28-day toxicity study on adult male rats. - Highlights: • Dose–response characterization of endocrine mediated toxicity is an on-going debate. • A wide range of dose levels of flutamide was evaluated on young adult male rats. • Flutamide induces threshold effects using on standard and molecular tools.« less
DOE Office of Scientific and Technical Information (OSTI.GOV)
Lesht, B.M.; Liljegren, J.C.
1996-12-31
Comparisons between the precipitable water vapor (PWV) estimated by passive microwave radiometers (MWRs) and that obtained by integrating the vertical profile of water vapor density measured by radiosondes (BBSS) have generally shown good agreement. These comparisons, however, have usually been done over rather short time periods and consequently within limited ranges of total PWV and with limited numbers of radiosondes. We have been making regular comparisons between MWR and BBSS estimates of PWV at the Southern Great Plains Cloud and Radiation Testbed (SGP/CART) site since late 1992 as part of an ongoing quality measurement experiment (QME). This suite of comparisonsmore » spans three annual cycles and a relatively wide range of total PWV amounts. Our findings show that although for the most part the agreement is excellent, differences between the two measurements occur. These differences may be related to the MWR retrieval of PWV and to calibration variations between radiosonde batches.« less
Composite Characterization Using Ultrasonic Wavefield Techniques
NASA Technical Reports Server (NTRS)
Leckey, Cara A. C.; Juarez, Peter D.; Seebo, Jeffrey P.
2016-01-01
The large-scale use of composite components in aerospace applications is expected to continue due to the benefits of composite materials, such as reduced weight, increased strength, and tailorability. NASA's Advanced Composites Project (ACP) has the goals of reducing the timeline for certification of composite materials and enabling the expanded use of advanced composite materials. A key technical challenge area for accomplishing these goals is the need for nondestructive evaluation and materials characterization techniques that are optimized for rapid inspection and detailed defect/damage characterization in composite materials. This presentation will discuss ongoing research investigating the use of ultrasonic wavefield techniques for the characterization of defects such as fiber waviness and delamination damage. Ongoing work includes the development of realistic ultrasonic simulation tools for use in predicting the inspectability of composites and optimizing inspection methodologies. Recent studies on detecting/characterizing delamination damage and fiber waviness via wavefield methods will be described.
Using Baltimore HIV behavioral surveillance data for local HIV prevention planning.
German, Danielle; Linton, Sabriya; Cassidy-Stewart, Hope; Flynn, Colin
2014-04-01
In response to the National HIV/AIDS Strategy (NHAS) and as part of CDC's Enhanced Comprehensive HIV Prevention Plan (ECHPP) project, Maryland developed a comprehensive local HIV prevention plan for the Baltimore-Towson Metropolitan Statistical Area and identified a series of priority HIV prevention and service goals. The current project sought to: (1) determine how well National HIV Behavioral Surveillance (NHBS) indicators were aligned with NHAS/ECHPP-informed local HIV prevention goals (2) facilitate on-going NHBS data utilization to inform on-going local HIV prevention and service planning, and (3) build a foundation for future NHBS data utilization in local HIV decision-making. Project activities identified key HIV-related indicators in NHBS that are directly or indirectly related to local HIV priorities as informed by NHAS/ECHPP, which can be used for HIV prevention planning in the Baltimore area. Areas for enhancing NHBS and local data collection to further inform HIV prevention priorities are highlighted.
Analyzing the Interprofessional Working of a Home-Based Primary Care Team.
Smith-Carrier, Tracy; Neysmith, Sheila
2014-09-01
Increasingly, interprofessional teams are responsible for providing integrated health care services. Effective teams, however, are not the result of chance but require careful planning and ongoing attention to team processes. Based on a case study involving interviews, participant observation, and a survey, we identified key attributes for effective interprofessional working (IPW) within a home-based primary care (HBPC) setting. Recognizing the importance of a theoretical model that reflects the multidimensional nature of team effectiveness research, we employed the integrated team effectiveness model to analyze our findings. The results indicated that a shared vision, common goals, respect, and trust among team members – as well as processes for ongoing communication, effective leadership, and mechanisms for conflict resolution – are vital in the development of a high-functioning IPW team. The ambiguity and uncertainty surrounding the context of service provision (clients' homes), as well the negotiation of external relationships in the HBPC field, require further investigation.
Lee, Su Jin; Lim, Ho Yeong
2017-06-01
Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. Over the last decade, sorafenib has been the only available therapeutic option for advanced HCC, although regorafenib recently showed a survival benefit compared with placebo in a second-line setting. Areas covered: This review discusses key published and ongoing studies with targeted agents in HCC, molecular targets of HCC, the mechanism of resistance to sorafenib, and the role of biomarker-enriched clinical trials. Expert opinion: The multiplicity of drivers and the existence of substantial molecular heterogeneity limit the benefits of targeted therapies in HCC. Based on molecular biology developments, a few biomarker-enriched clinical trials that target candidate driver genes are ongoing, and the outcomes of these are highly anticipated. Poor availability of tumor tissue and tumor heterogeneity in patients with HCC make liquid biopsy a very attractive option, although this technique remains to be validated.
Medicalized Female Genital Mutilation/Cutting: Contentious Practices and Persistent Debates.
Kimani, Samuel; Shell-Duncan, Bettina
2018-01-01
Female genital cutting/mutilation (FGM/C) performed by health care professionals (medicalization) and reduced severity of cutting have been advanced as strategies for minimizing health risks, sparking acrimonious ongoing debates. This study summarizes key debates and critically assesses supporting evidence. While medicalization is concentrated in Africa, health professionals worldwide have faced requests to perform FGM/C. Whether medicalization is hindering the decline of FGM/C is unclear. Factors motivating medicalization include, but are not limited to, safety concerns. Involvement of health professionals in advocacy to end FGM/C can address both the supply and demand side of medicalization, but raises ethical concerns regarding dual loyalty. Ongoing debates need to address competing rights claims. Polarizing debates have brought little resolution. We call for a focus on common goals of protecting the health and welfare of girls living in communities where FGM/C is upheld and encourage more informed and open dialog.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Brunett, A. J.; Fanning, T. H.
The United States has extensive experience with the design, construction, and operation of sodium cooled fast reactors (SFRs) over the last six decades. Despite the closure of various facilities, the U.S. continues to dedicate research and development (R&D) efforts to the design of innovative experimental, prototype, and commercial facilities. Accordingly, in support of the rich operating history and ongoing design efforts, the U.S. has been developing and maintaining a series of tools with capabilities that envelope all facets of SFR design and safety analyses. This paper provides an overview of the current U.S. SFR analysis toolset, including codes such asmore » SAS4A/SASSYS-1, MC2-3, SE2-ANL, PERSENT, NUBOW-3D, and LIFE-METAL, as well as the higher-fidelity tools (e.g. PROTEUS) being integrated into the toolset. Current capabilities of the codes are described and key ongoing development efforts are highlighted for some codes.« less
NASA Astrophysics Data System (ADS)
Allal, Djamel; Achkar, Joseph
2006-01-01
An international comparison of thermal noise-power measurements has been carried out among five national metrology institutes between 12.4 GHz and 18 GHz. Four transfer standards were measured. The following national institutes participated: BNM-LCIE (France), NPL (United Kingdom), PTB (Germany), NIST (United States of America) and VNIIFTRI (Russia). The Bureau National de Métrologie-Laboratoire Central des Industries Electriques (France) acted as the pilot laboratory for the comparison. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCEM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Allisy-Roberts, P. J.; Kessler, C.; Toni, M.; Bovi, M.
2010-01-01
A comparison of the standards of air kerma of the Istituto Nazionale di Metrologia delle Radiazioni Ionizzanti of the Ente per le Nuove Tecnologie, l'Energia e l'Ambiente, Italy (ENEA-INMRI) and of the Bureau International des Poids et Mesures (BIPM) was carried out in 137Cs radiation in 1998. The comparison result, updated for changes in the standards in 2003 and 2009, is 0.9927 (0.0067) and demonstrates that the ENEA-INMRI and BIPM standards are in agreement within the uncertainties. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI Section I, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
Quality Management and Key Performance Indicators in Oncologic Esophageal Surgery.
Gockel, Ines; Ahlbrand, Constantin Johannes; Arras, Michael; Schreiber, Elke Maria; Lang, Hauke
2015-12-01
Ranking systems and comparisons of quality and performance indicators will be of increasing relevance for complex "high-risk" procedures such as esophageal cancer surgery. The identification of evidence-based standards relevant for key performance indicators in esophageal surgery is essential for establishing monitoring systems and furthermore a requirement to enhance treatment quality. In the course of this review, we analyze the key performance indicators case volume, radicality of resection, and postoperative morbidity and mortality, leading to continuous quality improvement. Ranking systems established on this basis will gain increased relevance in highly complex procedures within the national and international comparison and furthermore improve the treatment of patients with esophageal carcinoma.
Social Comparison Processes in Organizations
ERIC Educational Resources Information Center
Greenberg, Jerald; Ashton-James, Claire E.; Ashkanasy, Neal M.
2007-01-01
We systematically analyze the role of social comparison processes in organizations. Specifically, we describe how social comparison processes have been used to explain six key areas of organizational inquiry: (1) organizational justice, (2) performance appraisal, (3) virtual work environments, (4) affective behavior in the workplace, (5) stress,…
Meyer, C W; Solano, A
2016-01-01
A Regional Metrology Organization (RMO) Key Comparison of dew/frost point temperatures over the range -30 °C TO +20 °C was carried out by the National Institute of Standards and Technology (NIST, USA) and the Laboratorio Costarricense de Metrología (LACOMET, Costa Rica), between February 2015 and August 2015. The results of this comparison are reported here, along with descriptions of the humidity laboratory standards for NIST and LACOMET and the uncertainty budget for these standards. This report also describes the protocol for the comparison and presents the data acquired. The results are analyzed, determining the degree of equivalence between the dew/frost-point standards of NIST and LACOMET.
Meyer, C.W.; Solano, A.
2016-01-01
A Regional Metrology Organization (RMO) Key Comparison of dew/frost point temperatures over the range −30 °C TO +20 °C was carried out by the National Institute of Standards and Technology (NIST, USA) and the Laboratorio Costarricense de Metrología (LACOMET, Costa Rica), between February 2015 and August 2015. The results of this comparison are reported here, along with descriptions of the humidity laboratory standards for NIST and LACOMET and the uncertainty budget for these standards. This report also describes the protocol for the comparison and presents the data acquired. The results are analyzed, determining the degree of equivalence between the dew/frost-point standards of NIST and LACOMET. PMID:28066029
NASA Astrophysics Data System (ADS)
Chalyy, V.
2011-01-01
A bilateral regional comparison of national microphone standards from 2 Hz to 250 Hz was carried out between the DP NDI 'Systema' (Ukraine) and the VNIIFTRI (Russia) from July to September 2009. The comparison, COOMET.AUV.A-K2, was based on the pressure calibration of laboratory standard microphones type LSIP. The comparison results have been linked to the established key comparison reference value (KCRV) of CCAUV.A-K2. The degrees of equivalence, expressed as the deviation from the established KCRV and its expanded uncertainty (k = 2), have been determined, and the comparison result is in agreement with the KCRV within the estimated uncertainties at all employed frequencies. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCAUV, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Hill, K. D.; Steele, A. G.; Dedikov, Y. A.; Shkraba, V. T.
2005-01-01
The Consultative Committee for Thermometry Key Comparison 2 (CCT-K2) results were published two years ago (2002 Metrologia 39 551-71). NRC served as the pilot laboratory for CCT-K2 and remains able to provide a scale and measurement system suitable for performing bilateral comparisons linked to the original key comparison results. In March 2003, measurements of two VNIIFTRI 100 Ω capsule-style platinum resistance thermometers (CSPRTs), S/N 356 and 476, were undertaken to relate their local calibration to the results from the CCT-K2 exercise. The NRC Leeds and Northrup (L&N) CSPRT S/N 1872174 provides the link to the CCT-K2 results. The three CSPRTs were compared at the eight defining cryogenic temperatures of the International Temperature Scale of 1990 (ITS-90) in the range from 13.8033 K to 273.16 K. The reader is referred to the full text of the CCT-K2 report for a detailed explanation of the methodology employed for the comparison. Only the details unique to the measurements reported here will be addressed in this article. The NRC/VNIIFTRI bilateral comparison of capsule-style platinum resistance thermometers over the range 13.8 K to 273.16 K has revealed calibrations at VNIIFTRI to be in agreement with the KCRV of CCT-K2 within the expanded uncertainty for all temperatures of the comparison with the exception of the triple point of hydrogen at 13.8033 K. One of the two CSPRTs supplied by VNIIFTRI was found to be discrepant as revealed by differences at the triple point of water and at the lowest temperatures of the comparison, and was therefore excluded from further analysis. The linkage to the CCT-K2 data supports the evaluation of the VNIIFTRI CMCs in Appendix C of the KCDB. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Spitzer, Petra; Giera, Janine; Fraga, Isabel C.; Tønnes Jakobsen, Pia; Jensen, Hans D.; Hyllested, Peter; Karpov, Oleg; Kutovoy, Viatcheslav; Nakamura, Susumu; Vospelova, Alena; Zvezdina, Valentina
2008-01-01
CCQM-K9.2 was performed supplementary to the key comparison CCQM-K9 on the pH determination of a phosphate buffer with nominal pH ~ 6.9 (at 25 °C). The sample composition was very similar in both comparisons. Only the source of the starting material used for sample preparation was different. The comparison was restricted to the use of the primary method for pH (Harned cell measurement) as defined in the IUPAC Recommendations [2]. The measurement temperatures were 15 °C, 25 °C, 37 °C. CCQM-K9.2, CCQM-K.9 and the first supplementary comparison CCQM-K9.1 [5] are activities of the Electrochemical Working Group (EAWG) of the CCQM. All three comparisons were coordinated by the PTB, Germany. The Danish Primary Laboratory (DPL) successfully took part in the CCQM-K9. Meanwhile the primary set-up for pH in Denmark moved from DPL affiliated to Radiometer Medical to DFM, Denmark. The subsequent comparison allows assessing the degree of equivalence for the measurement of pH at DFM after the move. Due to the interest of other laboratories in demonstrating their progress in pH measurements on the primary level the CCQM-K9.2 supplementary comparison was extended to other participants than DFM, namely NMIJ, VNIIFTRI, INMETRO and CMI. The reported quantity for CCQM-K9.2 was not the pH of the sample but the acidity function at zero chloride molality (see chapter 12). To calculate the pH value from the acidity function it is necessary to know the ionic strength of the sample buffer solution, which was undisclosed by the coordinator. With the exception of the Czech Metrology Institute, CMI, good agreement in the determined acidity function is found between the participants. The results reported by DFM and by PTB agree within their measurement uncertainty at all measurement temperatures. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Colín, C.; Viliesid, M.; Chaudhary, K. P.; Decker, J.; Dvorácek, F.; Franca, R.; Ilieff, S.; Rodríguez, J.; Stoup, J.
2012-01-01
This Key Comparison of gauge blocks (GB) calibration by optical interferometry was carried out to support this Calibration and Measurement Capability (CMC) of the National Measurement Institutes (NMI) from the SIM Region for this specific service and for those that rely on this kind of technique as required by the Mutual Recognition Arrangement (MRA). It provides evidence of the participant's technical competence and supports the uncertainties they state in their CMC. It is a Regional Key Comparison and should be linked to the upper level corresponding comparison CCL-K1. The comparison had nine participants, five from the SIM Region—NRC-CNRC, Canada; NIST, USA; CENAM, Mexico; INMETRO, Brazil; and INTI, Argentina— and four from other regions—CMI, Czech Rep.; CEM, Spain; NPLI, India; and NMISA South Africa. It included the circulation of fourteen GB—seven steel GB and seven ceramic GB. The circulation of the artifacts started on 2007-11-01 and ended on 2010-04-25. Some additional time was required to publish the results as the same artifacts were used thereafter for comparison SIM.L-S6, Calibration of GB by mechanical comparison, and the results could not be disclosed until the participants of the second circulation loop had sent their results. The final report of this comparison was sent out for review in May 2012 and the final version was approved in August 2012. The behavior of the artifacts throughout the circulation was good and therefore the results obtained were judged technically valid. The reference value was taken as arithmetic mean of the largest subset of consistent results. Most of participates obtained results in good agreement with the reference values with a few exceptions mentioned in the report. The corresponding NMIs are responsible for identifying the causes and taking corrective action. This makes the present comparison exercise valid to support the CMC claims of the participants in GB calibration by optical interferometry. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCL, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Final report on APMP.T-K7 key comparison of water triple point cells
NASA Astrophysics Data System (ADS)
Tsai, S. F.; White, R.; Tamba, J.; Yamazawa, K.; Ho, M. K.; Tsui, C. M.; Zaid, G.; Achmadi, A.; Gam, K. S.; Othman, H.; Ali, N. M.; Yuan, K. H.; Shaochun, Y.; Liedberg, H.; Yaokulbodee, C.
2016-01-01
APMP.T-K7, was held from February 2008 to September 2009 to compare the national realizations of the water triple point among eleven NMIs. To reach the objective, each participating laboratory sent a transfer cell to CMS and stated a value for the temperature difference of the transfer cell, relative to the corresponding national standard, representing 273.16 K. CMS (Taiwan) organized the comparison, with the support from co-pilot institutes MSL (New Zealand) and NMIJ (Japan). The other eight participating laboratories included NMIA, SCL, KIM-LIPI, KRISS, NMIM/SIRIM, NMC, NMISA, and NIMT. This report presents the results of the TPW comparison, gives detailed information about the measurements made at the CMS and at the participating laboratories, and aims to link the results of APMP.T-K7 to CCT-K7. The results of this key comparison are also represented in the form of degrees of equivalence for the purposes of the MRA. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Final report on the key comparison, CCM.P-K15 in the pressure range from 1.0 × 10-4 Pa to 1.0 Pa
NASA Astrophysics Data System (ADS)
Wuethrich, Christian; Arai, Kenta; Bergoglio, Mercede; Fedchak, James A.; Jousten, Karl; Hong, Seung Soo; Torres Guzman, Jorge
2017-01-01
The comparison CCM.P-K15 is a key comparison in pressure involving six laboratories in three regional metrological organizations (RMO). The measurand of the comparison is the accommodation coefficient of two spinning rotating gauge characterized in nitrogen from 0.1 mPa up to 1.0 Pa. The two transfer standards were circulated from November 2009 until March 2011. The circulation consisted of three loops, one for each RMO, and a new calibration by the pilot be-tween each loop. The stability of one of the transfer standards was poor and was worse than expected based on the previous history of the transfer standard while the other transfer standard demonstrated good stability while circulated in Europe and America and a fair stability while circulated in Asia. All the participants demonstrated equivalence to the definition of pressure in their respective primary standards. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Woolford, Alison; Holden, Marcia; Salit, Marc; Burns, Malcolm; Ellison, Stephen L. R.
2009-01-01
Key comparison CCQM-K61 was performed to demonstrate and document the capability of interested national metrology institutes in the determination of the quantity of specific DNA target in an aqueous solution. The study provides support for the following measurement claim: "Quantitation of a linearised plasmid DNA, based on a matched standard in a matrix of non-target DNA". The comparison was an activity of the Bioanalysis Working Group (BAWG) of the Comité Consultatif pour la Quantité de Matière and was coordinated by NIST (Gaithersburg, USA) and LGC (Teddington, UK). The following laboratories (in alphabetical order) participated in this key comparison. DMSC (Thailand); IRMM (European Union); KRISS (Republic of Korea); LGC (UK); NIM (China); NIST (USA); NMIA (Australia); NMIJ (Japan); VNIIM (Russian Federation) Good agreement was observed between the reported results of all nine of the participants. Uncertainty estimates did not account fully for the dispersion of results even after allowance for possible inhomogeneity in calibration materials. Preliminary studies suggest that the effects of fluorescence threshold setting might contribute to the excess dispersion, and further study of this topic is suggested Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
NASA Astrophysics Data System (ADS)
Konopelko, L. A.; Kustikov, Y. A.; Kolobova, A. V.; Shor, N. B.; Efremova, O. V.; Rozhnov, M. S.; Melnyk, D. M.; Kozia, V. G.; Shpilnyi, S. A.; Petryshyn, P. V.; Iakubov, S. E.; Kluchits, A. S.; Ananyin, V. N.; Mironchik, A. M.; Mokhnach, M. V.; Valkova, M.; Stovcik, V.
2014-01-01
Sulfur dioxide is one of the main contaminants present in the atmosphere due to burning of coal, oil and natural gas, smelting of base metals and production of sulfuric acid. Sulfur dioxide has been the subject of three previous CCQM key comparisons: CCQM-K1.d in 1997, CCQM-K26.b in 2005 and CCQM-K76 in 2010. VNIIM proposed a new COOMET project (No 484/RU/09) in this field, which was registered in the KCDB as key comparison COOMET.QM-K76. It was found that all results were consistent with the reference (gravimetric) values, with observed differences not exceeding ±0.60% and not exceeding either the appropriate assigned expanded uncertainties. VNIIM is the linking laboratory to CCQM-K76. SMU has improved the results obtained in CCQM-K76. The mixtures prepared for this exercise were found to be stable during about one year within the uncertainty of the measurements. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Utilization of Phase Change Materials (PCM) to Reduce Energy Consumption in Buildings
2011-09-14
incorporating PCM for use in building applications. Ongoing research in thermal storage in which the PCM were encapsulated in concrete, gypsum wallboard ... wallboards were made from commercial panels after a first attempt to use gypsum walls. Three types of wallboards were studied: (i) a polycarbonate panel...and compared with ordinary gypsum wallboard . Within this comparison, the PCM composite solidification temperature was 22 °C (i.e. 2 K higher than the
Current Simulation Methods in Military Systems Vulnerability Assessment
1990-11-01
Weapons * 1990: JASON Review of the Army Approach to Vulnerability Testing Many of the suggestions and recommendations made by these committees concern...damage vectors. Ongoing work by the JASONs 29 is also targeted to developing statistical methods for LF-test/SQuASH-model comparisons in Space 2]. We...Technical Report BRL-TR-3113, June 1990. 28. L. Tonnessen, A. Fries , L. Starkey and A. Stein, Live Fire Testing in the Evaluation of the Vulnerability of
ERIC Educational Resources Information Center
General Accounting Office, Washington, DC.
A study compared the compensation packages offered to private sector and Federal white-collar employees. The conclusions drawn in the study were based on data from previous and ongoing research conducted by the General Accounting Office (GAO). Analysis of these data revealed that whereas the Employment Cost Index has shown a cumulative increase of…
van der Molen, Thys; van Boven, Job F M; Maguire, Terence; Goyal, Pankaj; Altman, Pablo
2017-01-01
The aim of this paper was to propose key steps for community pharmacist integration into a patient care pathway for chronic obstructive pulmonary disease (COPD) management. A literature search was conducted to identify publications focusing on the role of the community pharmacist in identification and management of COPD. The literature search highlighted evidence supporting an important role for pharmacists at each of the four key steps in the patient care pathway for COPD management. Step 1 (primary prevention): pharmacists are ideally placed to provide information on disease awareness and risk prevention campaigns, and to encourage lifestyle interventions, including smoking cessation. Step 2 (early detection/case finding): pharmacists are often the first point of contact between the patient and the healthcare system and can therefore play an important role in the early identification of patients with COPD. Step 3 (management and ongoing support): pharmacists can assist patients by providing advice and education on dosage, inhaler technique, treatment expectations and the importance of adherence, and by supporting self-management, including recognition and treatment of COPD exacerbations. Step 4 (review and follow-up): pharmacists can play an important role in monitoring adherence and ongoing inhaler technique in patients with COPD. In summary, pharmacists are ideally positioned to play a vital role in all key stages of an integrated COPD patient care pathway from early disease detection to the support of management plans, including advice and counselling regarding medications, inhaler technique and treatment adherence. Areas requiring additional consideration include pharmacist training, increasing awareness of the pharmacist role, administration and reimbursement, and increasing physician-pharmacist collaboration. © 2016 The Authors. British Journal of Clinical Pharmacology published by John Wiley & Sons Ltd on behalf of British Pharmacological Society.
Magnus, Manya; Franks, Julie; Griffith, Sam; Arnold, Michael P.; Goodman, Krista; Wheeler, Darrell P.
2014-01-01
Context HIV/AIDS in the United States continues to primarily impact men who have sex with men (MSM), with disproportionately high rates among black MSM. Objective The purpose of this study was to identify factors that may influence engagement and retention of black MSM in HIV research. Design and Participants This was a qualitative evaluation of study implementation within a multisite, prospective, observational study (HIV Prevention Trials Network 061, BROTHERS) that enrolled 1553 black MSM in 6 cities throughout the United States. Data collection for this evaluation included a written, structured survey collected from each of the sites describing site characteristics including staff and organizational structure, reviews of site standard operating procedures, and work plans; semistructured key informant interviews were conducted with site coordinators to characterize staffing, site-level factors facilitating or impeding effective community engagement, study recruitment, and retention. Data from completed surveys and site standard operating procedures were collated, and notes from key informant interviews were thematically coded for content by 2 independent reviewers. Results Several key themes emerged from the data, including the importance of inclusion of members of the community being studied as staff, institutional hiring practices that support inclusive staffing, cultivating a supportive working environment for study implementation, and ongoing relationships between research institutions and community. Conclusions This study underscores the importance of staffing in implementing research with black MSM. Investigators should consider how staffing and organizational structures affect implementation during study design and when preparing to initiate study activities. Ongoing monitoring of community engagement can inform and improve methods for engagement and ensure cultural relevance while removing barriers for participation. PMID:24406940
Magnus, Manya; Franks, Julie; Griffith, Sam; Arnold, Michael P; Goodman, Krista; Wheeler, Darrell P
2014-01-01
HIV/AIDS in the United States continues to primarily impact men who have sex with men (MSM), with disproportionately high rates among black MSM. The purpose of this study was to identify factors that may influence engagement and retention of black MSM in HIV research. This was a qualitative evaluation of study implementation within a multisite, prospective, observational study (HIV Prevention Trials Network 061, BROTHERS) that enrolled 1553 black MSM in 6 cities throughout the United States. Data collection for this evaluation included a written, structured survey collected from each of the sites describing site characteristics including staff and organizational structure, reviews of site standard operating procedures, and work plans; semistructured key informant interviews were conducted with site coordinators to characterize staffing, site-level factors facilitating or impeding effective community engagement, study recruitment, and retention. Data from completed surveys and site standard operating procedures were collated, and notes from key informant interviews were thematically coded for content by 2 independent reviewers. Several key themes emerged from the data, including the importance of inclusion of members of the community being studied as staff, institutional hiring practices that support inclusive staffing, cultivating a supportive working environment for study implementation, and ongoing relationships between research institutions and community. This study underscores the importance of staffing in implementing research with black MSM. Investigators should consider how staffing and organizational structures affect implementation during study design and when preparing to initiate study activities. Ongoing monitoring of community engagement can inform and improve methods for engagement and ensure cultural relevance while removing barriers for participation.
Framework for Processing Citizens Science Data for Applications to NASA Earth Science Missions
NASA Technical Reports Server (NTRS)
Teng, William; Albayrak, Arif
2017-01-01
Citizen science (or crowdsourcing) has drawn much high-level recent and ongoing interest and support. It is poised to be applied, beyond the by-now fairly familiar use of, e.g., Twitter for natural hazards monitoring, to science research, such as augmenting the validation of NASA earth science mission data. This interest and support is seen in the 2014 National Plan for Civil Earth Observations, the 2015 White House forum on citizen science and crowdsourcing, the ongoing Senate Bill 2013 (Crowdsourcing and Citizen Science Act of 2015), the recent (August 2016) Open Geospatial Consortium (OGC) call for public participation in its newly-established Citizen Science Domain Working Group, and NASA's initiation of a new Citizen Science for Earth Systems Program (along with its first citizen science-focused solicitation for proposals). Over the past several years, we have been exploring the feasibility of extracting from the Twitter data stream useful information for application to NASA precipitation research, with both "passive" and "active" participation by the twitterers. The Twitter database, which recently passed its tenth anniversary, is potentially a rich source of real-time and historical global information for science applications. The time-varying set of "precipitation" tweets can be thought of as an organic network of rain gauges, potentially providing a widespread view of precipitation occurrence. The validation of satellite precipitation estimates is challenging, because many regions lack data or access to data, especially outside of the U.S. and in remote and developing areas. Mining the Twitter stream could augment these validation programs and, potentially, help tune existing algorithms. Our ongoing work, though exploratory, has resulted in key components for processing and managing tweets, including the capabilities to filter the Twitter stream in real time, to extract location information, to filter for exact phrases, and to plot tweet distributions. The key step is to process the "precipitation" tweets to be compatible with satellite-retrieved precipitation data. These key components for processing and managing "precipitation" tweets (and additional ones to be developed) are not limited to precipitation, nor are they limited to the Twitter social medium. Indeed, to maximize the value of our work for NASA earth science programs, these components should be generalized and be part of an overall framework for processing citizen science data for science research. In this paper, we outline such a framework.
Contaminant and other elements in soil (CCQM-K127)
NASA Astrophysics Data System (ADS)
Rocio Arvizu Torres, M.; Manzano, J. Velina Lara; Valle Moya, Edith; Horvat, Milena; Jaćimović, Radojko; Zuliani, Tea; Vreča, Polona; Acosta, Osvaldo; Bennet, John; Snell, James; Almeida, Marcelo D.; de Sena, Rodrigo C.; Dutra, Emily S.; Yang, Lu; Li, Haifeng
2017-01-01
Non-contaminated soils contain trace and major elements at levels representing geochemical background of the region. The main sources of elements as contaminants/pollutants in soils are mining and smelting activities, fossil fuel combustion, agricultural practices, industrial activities and waste disposal. Contaminated/polluted sites are of great concern and represent serious environmental, health and economic problems. Characterization and identification of contaminated land is the first step in risk assessment and remediation activities. It is well known that soil is a complex matrix with huge variation locally and worldwide. According to the IAWG's five year plan, it is recommended to have a key comparison under the measurement service category of soils and sediments for the year 2015. Currently 13 NMI has claimed calibration and measurement capabilities (CMCs) in category 13 (sediments, soils, ores, and particulates): 29 CMCs in soil and 96 CMCs in sediments. In this regard this is a follow-up comparison in the category 13; wherein three key comparisons have been carried out during the years 2000 (CCQM-K13), 2003 (CCQM-K28) and 2004 (CCQM-K44). Since it is important to update the capabilities of NMIs in this category. CENAM and JSI proposed a key comparison in this category and a pilot study in parallel. The proposed study was agreed by IAWG members, where two soils samples were used in both CCQM-K127 representing a non-contaminated soil with low contents of elements (arsenic, cadmium, iron, lead and manganese), and a contaminated soil with much higher content of selected elements (arsenic, cadmium, iron and lead). This broadens the scope and a degree of complexity of earlier measurements in this field. National metrology institutes (NMIs)/designate institutes (DIs) should, therefore, demonstrate their measurement capabilities of trace and major elements in a wide concentration ranges, representing background/reference sites as well as highly contaminated soils by their available analytical methods. This facilitated the investigation into the core capabilities of participants to measure the mass fraction of tested elements in soil and therefore to claim their CMCs as listed in appendix C of the key comparison database (KCDB) under the mutual recognition arrangement of the International Committee for Weights and Measures (CIPM MRA). In total 19 institutes (NMIs/Dis) participated in the key comparison and the reported results of the key comparison were from 18 institutes (NMIs/DIs); 151 measurements were reported for CCQM-K127. The analytical techniques selected by the participant institutes were ICP-MS, ICP-OES, FAAS, ET-AAS and INAA (k0-method of INAA); the sample preparation methods used were based on microwave assisted digestion, except when it was used INAA. After discussions it agreed to use the median as KCRV and the MMADe as u(xKCRV). Generally most of the results of the participants were found to be consistent for all measurements according to their equivalence statements, with the exception of some extreme values, which were identified with a value of di/U(di) higher than 1. This key comparison is a means of providing evidence for practical demonstration of a CCQM comparison calibration and measurement capabilities (CMCs) claims for contaminant and others elements, in low and medium content levels in non-contaminated and contaminated matrices described in category 13. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Light-neuron interactions: key to understanding the brain
NASA Astrophysics Data System (ADS)
Go, Mary Ann; Daria, Vincent R.
2017-02-01
In recent years, advances in light-based technology have driven an ongoing optical revolution in neuroscience. Synergistic technologies in laser microscopy, molecular biology, organic and synthetic chemistry, genetic engineering and materials science have allowed light to overcome the limitations of and to replace many conventional tools used by physiologists to record from and to manipulate single cells or whole cellular networks. Here we review the different optical techniques for stimulating neurons, influencing neuronal growth, manipulating neuronal structures and neurosurgery.
Challenges to deployment of twenty-first century nuclear reactor systems
2017-01-01
The science and engineering of materials have always been fundamental to the success of nuclear power to date. They are also the key to the successful deployment and operation of a new generation of nuclear reactor systems and their associated fuel cycles. This article reflects on some of the historical issues, the challenges still prevalent today and the requirement for significant ongoing materials R&D and discusses the potential role of small modular reactors. PMID:28293142
Considerations for preparing collaborative international research: a Ugandan experience.
Musil, Carol M; Mutabaazi, Jemimah; Walusimbi, Mariam; Okonsky, Jennifer G; Biribonwa, Yedidah; Eagan, Sabrina; Dimarco, Marguerite A; Mbaballi, Speciosa; Fitzpatrick, Joyce J
2004-08-01
This article describes issues to consider when planning and conducting international research projects. Key considerations include building collaboration, developing a comprehensive and feasible research plan, funding and budgets, addressing human subjects concerns, and analyzing and disseminating project findings. These considerations and related methodological issues are discussed in the context of a replication pilot project conducted outside Kampala, Uganda. Ongoing dialog, flexibility, and collaboration, in addition to good science, are critical to developing successful international research projects.
A Critical Examination of the DOD’s Business Management Modernization Program
2005-05-01
Program (BMMP) is a key element of the DoD’s ongoing efforts to transform itself. This paper argues that the BMMP needs to be fundamentally reoriented...communication role it plays in the defense- transformation effort. Introduction The core assumption underlying the DoD’s Business Management... government activities. That this is a core assumption for the BMMP is borne out by the fact that the program’s primary objective is to produce
Survival benefit of surgery in recurrent glioblastoma multiforme.
Choudry, Usama Khalid; Khan, Saad Akhtar; Shamim, Muhammad Shahzad
2017-12-01
There is an ongoing debate regarding role of surgery for recurrent glioblastoma multiforme (GBM). Older literature hinted at only modest survival benefits with surgery and a high rate of morbidity. However, more recent literature suggests better survival that may be attributed to better surgical techniques and better options in adjuvant treatment. Herein the authors review recent literature with regards to the possible role of surgery in recurrent GBM and also look into the key factors impacting second surgery. .
NASA Astrophysics Data System (ADS)
Uffelman, Erich S.; Hobbs, Patricia A.; Barisas, Derek A. G.; Mass, Jennifer L.
2013-04-01
Portable X-ray Fluorescence Spectrometry (pXRF) was used to survey 33 works in Washington and Lee University's collection of Louise Herreshoff's paintings. This work was done both to support a condition assessment of the paintings and their pigments and to determine which paintings might be appropriate for further study in the context of ongoing key synchrotron research into the degradation mechanisms of cadmium sulfide yellow pigment (CdS).
Challenges to deployment of twenty-first century nuclear reactor systems.
Ion, Sue
2017-02-01
The science and engineering of materials have always been fundamental to the success of nuclear power to date. They are also the key to the successful deployment and operation of a new generation of nuclear reactor systems and their associated fuel cycles. This article reflects on some of the historical issues, the challenges still prevalent today and the requirement for significant ongoing materials R&D and discusses the potential role of small modular reactors.
Planning a graduate programme in public health nutrition for experienced nutrition professionals.
Fox, Ann; Beyers, Joanne
2011-08-01
Public health renewal in Canada has highlighted the need for development and expansion of the public health nutrition workforce, particularly in northern and rural communities. The purpose of the present paper is to describe the planning of a more accessible graduate programme for experienced nutrition professionals. The planning effort was challenged by a short timeframe between programme approval and implementation and required intense collaboration with stakeholders and students. The programme planning model developed by The Health Communication Unit (THCU) at the Centre for Health Promotion was used to guide the process. This six-step model was familiar to key stakeholders and involved pre-planning, conducting a situational assessment, establishing goals and objectives, developing strategies and outcome indicators, and monitoring feedback. Resource constraints, short timelines and debates around distance education options presented challenges that were overcome by conducting a thorough needs assessment, creating an advisory committee, engaging key stakeholders in the planning process, and building on existing resources. Extensive involvement of the first cohort of students in ongoing planning and evaluation was particularly helpful in informing the evolution of the programme. The THCU planning model provided a useful framework for stakeholder collaboration and for planning and implementing the new graduate programme in public health nutrition. Preliminary data suggest that graduates are benefiting from their educational experiences through career enhancement opportunities. The evaluation strategies built into the programme design will be useful in informing ongoing programme development.
Final report on mid-polarity analytes in food matrix: mid-polarity pesticides in tea
NASA Astrophysics Data System (ADS)
Sin, Della W. M.; Li, Hongmei; Wong, S. K.; Lo, M. F.; Wong, Y. L.; Wong, Y. C.; Mok, C. S.
2015-01-01
At the Paris meeting in April 2011, the CCQM Working Group on Organic Analysis (OAWG) agreed on a suite of Track A studies meant to support the assessment of measurement capabilities needed for the delivery of measurement services within the scope of the OAWG Terms of Reference. One of the studies discussed and agreed upon for the suite of ten Track A studies that support the 5-year plan of the CCQM Core Competence assessment was CCQM-K95 'Mid-Polarity Analytes in Food Matrix: Mid-Polarity Pesticides in Tea'. This key comparison was co-organized by the Government Laboratory of Hong Kong Special Administrative Region (GL) and the National Institute of Metrology, China (NIM). To allow wider participation, a pilot study, CCQM-P136, was run in parallel. Participants' capabilities in measuring mid-polarity analytes in food matrix were demonstrated through this key comparison. Most of the participating NMIs/DIs successfully measured beta-endosulfan and endosulfan sulphate in the sample, however, there is room for further improvement for some participants. This key comparison involved not only extraction, clean-up, analytical separation and selective detection of the analytes in a complex food matrix, but also the pre-treatment procedures of the material before the extraction process. The problem of incomplete extraction of the incurred analytes from the sample matrix may not be observed simply by using spike recovery. The relative standard deviations for the data included in the KCRV calculation in this key comparison were less than 7 % which was acceptable given the complexity of the matrix, the level of the analytes and the complexity of the analytical procedure. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Hioki, Akiharu; Narukawa, Tomohiro; Inagaki, Kazumi; Miyashita, Shinichi; Kotzeva, Boriana; Kakoulides, Elias; Sxoina, Vasiliki; Fung, W. H.; Choi, Y. Y.; Yau, H. P.; Tsoi, Y. T.; Lee, C. L.; Kong, M. F.; Shin, Richard; Juan, Wang; Sin Yee, Ng; Uribe, Christian; Marques Rodrigues, Janaína; Caciano de Sena, Rodrigo; Silva Dutra, Emily; Bergamaschi, Luigi; Giordani, Laura; D'Agostino, Giancarlo; Valiente, Liliana; Horvat, Milena; Jacimovic, Radojko; Oduor Okumu, Tom; Kang'Iri, Jacqueline; Owiti Orwa, Tabitha; Chao, Wei; Jingbo, Chao; Taebunpakul, Sutthinun; Yafa, Charun; Kaewkhomdee, Nattikarn; Chailap, Benjamat; Pharat, Yanee; Phukphattanachai, Pranee; Turk, Gregory C.; Long, Stephen; Murphy, K. E.; Davis, Clay; Ellisor, Michael; Merrick, Jeffrey; White, Ian; Saxby, David; Linsky, S. M.; Barzev, A.; Botha, A.
2015-01-01
The CCQM-K108 key comparison was organised by the Inorganic Analysis Working Group (IAWG) of CCQM to test the abilities of national metrology institutes (NMIs) or designated institutes (DIs) to measure the mass fractions of arsenic species, total arsenic and cadmium in brown rice flour. The National Metrology Institute of Japan (NMIJ) acted as the coordinating laboratory. The participants used different measurement methods, though most of them used inductively coupled plasma mass spectrometry (ICP-MS) or isotope-dilution inductively coupled plasma mass spectrometry (ID-ICP-MS) for Cd and ICP-MS for total arsenic. Regarding arsenic speciation, all participants used ICP-MS coupled with liquid chromatography (LC). Accounting for relative expanded uncertainty, comparability of measurement results for each of total arsenic and cadmium was successfully demonstrated by the participating NMIs or DIs for the measurement of the measurand at the level of less than 0.5 mg/kg. Regarding arsenic species (inorganic arsenic and dimethylarsinic acid (DMAA)), there was, however, a measurement problem still to be solved and that part of CCQM-K108 will be repeated. It is expected that arsenic, cadmium and other metals at mass fractions greater than approximately 0.1 mg/kg in rice flour can be determined by each participant using the same technique(s) employed for this key comparison to achieve similar uncertainties mentioned in the present report. Furthermore, the results of this key comparison can be utilised along with the IAWG core capability approach. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Key properties of expert movement systems in sport : an ecological dynamics perspective.
Seifert, Ludovic; Button, Chris; Davids, Keith
2013-03-01
This paper identifies key properties of expertise in sport predicated on the performer-environment relationship. Weaknesses of traditional approaches to expert performance, which uniquely focus on the performer and the environment separately, are highlighted by an ecological dynamics perspective. Key properties of expert movement systems include 'multi- and meta-stability', 'adaptive variability', 'redundancy', 'degeneracy' and the 'attunement to affordances'. Empirical research on these expert system properties indicates that skill acquisition does not emerge from the internal representation of declarative and procedural knowledge, or the imitation of expert behaviours to linearly reduce a perceived 'gap' separating movements of beginners and a putative expert model. Rather, expert performance corresponds with the ongoing co-adaptation of an individual's behaviours to dynamically changing, interacting constraints, individually perceived and encountered. The functional role of adaptive movement variability is essential to expert performance in many different sports (involving individuals and teams; ball games and outdoor activities; land and aquatic environments). These key properties signify that, in sport performance, although basic movement patterns need to be acquired by developing athletes, there exists no ideal movement template towards which all learners should aspire, since relatively unique functional movement solutions emerge from the interaction of key constraints.
Leaks in the pipeline: separating demographic inertia from ongoing gender differences in academia
Shaw, Allison K.; Stanton, Daniel E.
2012-01-01
Identification of the causes underlying the under-representation of women and minorities in academia is a source of ongoing concern and controversy. This is a critical issue in ensuring the openness and diversity of academia; yet differences in personal experiences and interpretations have mired it in controversy. We construct a simple model of the academic career that can be used to identify general trends, and separate the demographic effects of historical differences from ongoing biological or cultural gender differences. We apply the model to data on academics collected by the National Science Foundation (USA) over the past three decades, across all of science and engineering, and within six disciplines (agricultural and biological sciences, engineering, mathematics and computer sciences, physical sciences, psychology, and social sciences). We show that the hiring and retention of women in academia have been affected by both demographic inertia and gender differences, but that the relative influence of gender differences appears to be dwindling for most disciplines and career transitions. Our model enables us to identify the two key non-structural bottlenecks restricting female participation in academia: choice of undergraduate major and application to faculty positions. These transitions are those in greatest need of detailed study and policy development. PMID:22719028
Immunotherapy in Gynecologic Cancers: Are We There Yet?
Pakish, Janelle B; Jazaeri, Amir A
2017-08-24
Immune-targeted therapies have demonstrated durable responses in many tumor types with limited treatment options and poor overall prognosis. This has led to enthusiasm for expanding such therapies to other tumor types including gynecologic malignancies. The use of immunotherapy in gynecologic malignancies is in the early stages and is an active area of ongoing clinical research. Both cancer vaccines and immune checkpoint inhibitor therapy continue to be extensively studied in gynecologic malignancies. Immune checkpoint inhibitors, in particular, hold promising potential in specific subsets of endometrial cancer that express microsatellite instability. The key to successful treatment with immunotherapy involves identification of the subgroup of patients that will derive benefit. The number of ongoing trials in cervical, ovarian, and endometrial cancer will help to recognize these patients and make treatment more directed. Additionally, a number of studies are combining immunotherapy with standard treatment options and will help to determine combinations that will enhance responses to standard therapy. Overall, there is much enthusiasm for immunotherapy approaches in gynecologic malignancies. However, the emerging data shows that with the exception of microsatellite unstable tumors, the use of single-agent immune checkpoint inhibitors is associated with response rates of 10-15%. More effective and likely combinatorial approaches are needed and will be informed by the findings of ongoing trials.
Brooks, T M; Cuttelod, A; Faith, D P; Garcia-Moreno, J; Langhammer, P; Pérez-Espona, S
2015-02-19
'Key biodiversity areas' are defined as sites contributing significantly to the global persistence of biodiversity. The identification of these sites builds from existing approaches based on measures of species and ecosystem diversity and process. Here, we therefore build from the work of Sgró et al. (2011 Evol. Appl. 4, 326-337. (doi:10.1111/j.1752-4571.2010.00157.x)) to extend a framework for how components of genetic diversity might be considered in the identification of key biodiversity areas. We make three recommendations to inform the ongoing process of consolidating a key biodiversity areas standard: (i) thresholds for the threatened species criterion currently consider a site's share of a threatened species' population; expand these to include the proportion of the species' genetic diversity unique to a site; (ii) expand criterion for 'threatened species' to consider 'threatened taxa' and (iii) expand the centre of endemism criterion to identify as key biodiversity areas those sites holding a threshold proportion of the compositional or phylogenetic diversity of species (within a taxonomic group) whose restricted ranges collectively define a centre of endemism. We also recommend consideration of occurrence of EDGE species (i.e. threatened phylogenetic diversity) in key biodiversity areas to prioritize species-specific conservation actions among sites.
Brooks, T. M.; Cuttelod, A.; Faith, D. P.; Garcia-Moreno, J.; Langhammer, P.; Pérez-Espona, S.
2015-01-01
‘Key biodiversity areas' are defined as sites contributing significantly to the global persistence of biodiversity. The identification of these sites builds from existing approaches based on measures of species and ecosystem diversity and process. Here, we therefore build from the work of Sgró et al. (2011 Evol. Appl. 4, 326–337. (doi:10.1111/j.1752-4571.2010.00157.x)) to extend a framework for how components of genetic diversity might be considered in the identification of key biodiversity areas. We make three recommendations to inform the ongoing process of consolidating a key biodiversity areas standard: (i) thresholds for the threatened species criterion currently consider a site's share of a threatened species' population; expand these to include the proportion of the species' genetic diversity unique to a site; (ii) expand criterion for ‘threatened species' to consider ‘threatened taxa’ and (iii) expand the centre of endemism criterion to identify as key biodiversity areas those sites holding a threshold proportion of the compositional or phylogenetic diversity of species (within a taxonomic group) whose restricted ranges collectively define a centre of endemism. We also recommend consideration of occurrence of EDGE species (i.e. threatened phylogenetic diversity) in key biodiversity areas to prioritize species-specific conservation actions among sites. PMID:25561678
Kim, Yong Jin; Shin, Jung Ho; Hur, Jun Yong; Kim, Hoon; Ku, Seung-Yup; Suh, Chang Suk
2017-01-01
To evaluate the predictive value of the progesterone level at the beta-human chorionic gonadotropin (β-hCG) check day for ongoing pregnancy maintenance in in vitro fertilization (IVF) cycles in women with previous unexplained repeated miscarriages. One hundred and forty-eight women, with visible gestational sac after IVF, were recruited in this observational study. All subjects had unexplained recurrent miscarriages in more than two previous IVF cycles. The progesterone level at the β-hCG check day (i.e. 14 days after oocyte retrieval) was assessed. The area under the curve (AUC) of the progesterone level was evaluated to predict the ongoing pregnancy or miscarriage outcomes. The overall ongoing pregnancy rate was 60.8% (90/148). The cut-off value with β-hCG levels higher than 126.5 mIU/mL and with progesterone levels higher than 25.2 ng/mL could be the predictive factors for ongoing pregnancy maintenance (AUC = 0.788 and 0.826; sensitivity = 0.788 and 0.723; specificity = 0.689 and 0.833; P < 0.0001 and P < 0.0001, respectively). The miscarriage rates were 19.5% (15/77) in the women with β-hCG > 126.5 mIU/mL and 13.0% (10/77) in those with > 25.2 ng/mL. In the comparison of the ROC curves between both values, a similar significance was found. The subjects with β-hCG > 126.5 mIU/mL and progesterone > 25.2 ng/mL showed higher ongoing pregnancy rates [98.0% (49/50) vs. 41.8% (41/98)] than those with β-hCG ≤ 126.5 mIU/mL or progesterone ≤ 25.2 ng/mL. The progesterone level at 14 days after oocyte retrieval can be a good predictive marker for ongoing pregnancy maintenance in women with repeated IVF failure with miscarriage, together with the β-hCG level. The combined cut-off value of progesterone > 25.2 ng/mL and β-hCG > 126.5 mIU/mL may suggest a good prognosis.
Comparison of measurement capability with 100 μmol/mol of carbon monoxide in nitrogen
NASA Astrophysics Data System (ADS)
Lee, Jeongsoon; Lee, JinBok; Lim, Jeongsik; Tarhan, Tanıl; Liu, Hsin-Wang; Aggarwal, Shankar G.
2018-01-01
Carbon monoxide (CO) in nitrogen was one of the first types of gas mixtures used in an international key comparison. The comparison dates back to 1998 (CCQMK1a) [1]. Since then, many National Metrology Institutes (NMIs) have developed calibration and measurement capabilities (CMCs) for these mixtures. Recently, NMIs in the APMP region have actively participated in international comparisons to provide domestic services. At the 2013 APMP meeting, several NMIs requested a CO comparison to establish CO/N2 certification for industrial applications, which was to be coordinated by KRISS. Consequently, this comparison provides an opportunity for APMP regional NMIs to develop CO/N2 CMC claims. The goal of this supplementary comparison is to support CMC claim for carbon monoxide in the N2 range of 50–2000 μmol/mol. An extended range may be supported as described in the GAWG strategy for comparisons and CMC claims. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
CCQM-K140: carbon stable isotope ratio delta values in honey
NASA Astrophysics Data System (ADS)
Dunn, P. J. H.; Goenaga-Infante, H.; Goren, A. C.; Şimşek, A.; Bilsel, M.; Ogrinc, N.; Armishaw, P.; Hai, L.
2017-01-01
As there can be small but measureable differences in isotope ratios between different sources of the same element/compound/material, isotope ratio measurements are applied in a number of different fields including archaeology, environmental science, geochemistry, forensic science and ecology. Isotope ratios for the light elements (H, C, N, O and S) are typically reported as δ-values which are isotope ratios expressed relative to an internationally agreed standard (this standard is the zero-point on the scale), although absolute isotope ratios which are traceable to the SI have also been reported. The IAWG has been granted a traceability exception for the use of arbitrary delta scales until SI traceability can be established at the required level of uncertainty but this goal is some years away. While the CCQM IAWG has previously organised several pilot studies on isotope ratio determination (CCQM-P75: Stable isotope delta values in methionine, 2006; CCQM-P105: Sr isotope ratios in wine, 2008; CCQM-K98: Pb isotope ratios in bronze with additional delta values in CCQM-P134, 2011), it has been a number of years since delta values of light elements have been considered and there has been no key comparison (KC). Therefore, the IAWG has included the need for a KC (CCQM-K140) based on an arbitrary delta scale in its program to support ongoing requirements to demonstrate core capabilities as well as specific claims of measurement capability (CMCs) in this area. The performance of all five of the CCQM-K140 participants was very good, illustrating their ability to obtain accurate results for carbon isotope ratios, within the calibration range afforded by internationally agreed reference materials (δ13CVPDB-LSVEC between -47.32 % and +535.3 %) with measurement uncertainties of between 0.08 and 0.28 %. This was despite the fact that no two participants used exactly the same approach in terms of instrumentation or data treatment. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
VHub - Cyberinfrastructure for volcano eruption and hazards modeling and simulation
NASA Astrophysics Data System (ADS)
Valentine, G. A.; Jones, M. D.; Bursik, M. I.; Calder, E. S.; Gallo, S. M.; Connor, C.; Carn, S. A.; Rose, W. I.; Moore-Russo, D. A.; Renschler, C. S.; Pitman, B.; Sheridan, M. F.
2009-12-01
Volcanic risk is increasing as populations grow in active volcanic regions, and as national economies become increasingly intertwined. In addition to their significance to risk, volcanic eruption processes form a class of multiphase fluid dynamics with rich physics on many length and time scales. Risk significance, physics complexity, and the coupling of models to complex dynamic spatial datasets all demand the development of advanced computational techniques and interdisciplinary approaches to understand and forecast eruption dynamics. Innovative cyberinfrastructure is needed to enable global collaboration and novel scientific creativity, while simultaneously enabling computational thinking in real-world risk mitigation decisions - an environment where quality control, documentation, and traceability are key factors. Supported by NSF, we are developing a virtual organization, referred to as VHub, to address this need. Overarching goals of the VHub project are: Dissemination. Make advanced modeling and simulation capabilities and key data sets readily available to researchers, students, and practitioners around the world. Collaboration. Provide a mechanism for participants not only to be users but also co-developers of modeling capabilities, and contributors of experimental and observational data sets for use in modeling and simulation, in a collaborative environment that reaches far beyond local work groups. Comparison. Facilitate comparison between different models in order to provide the practitioners with guidance for choosing the "right" model, depending upon the intended use, and provide a platform for multi-model analysis of specific problems and incorporation into probabilistic assessments. Application. Greatly accelerate access and application of a wide range of modeling tools and related data sets to agencies around the world that are charged with hazard planning, mitigation, and response. Education. Provide resources that will promote the training of the next generation of volcanologists and hazards specialists such that modeling and simulation form part of a tripartite foundation of approaches, alongside observational data and experimentation. Adaptation. Conduct ongoing, rigorous self-assessment to study the impact of the virtual organization and promote continual adaptation to optimize its impact, as well as to understand emergent collective learning and collaborative patterns. VHub development is just beginning and we are very interested in input from the community and the addition of new partners to the effort. Current partners include A. Costa, A. Neri, W. Marzocchi, R.S.J. Sparks, S.J. Cronin, S. Takarada, Joan Marti, J.-C. Komorowski, T.H. Druitt, T. Koyaguchi, J.L. Macias, and S. Dartevelle.
Sussman, S
2003-01-01
This paper provides a review of the last two and a half decades of research in adolescent and young-adult tobacco use cessation. A total of 66 tobacco cessation intervention studies – targeted or population – are reviewed. In addition, an exhaustive review is completed of adolescent self-initiated tobacco use cessation, involving 17 prospective survey studies. Average reach and retention across the intervention studies was 61% and 78%, respectively, and was higher when whole natural units were treated (e.g., classrooms), than when units created specifically for the program were treated (e.g., school-based clinics). The mean quit-rate at a three to 12-month average follow-up among the program conditions was 12%, compared to approximately 7% across control groups. A comparison of intervention theories revealed that motivation enhancement (19%) and contingency-based reinforcement (16%) programs showed higher quit-rates than the overall intervention cessation mean. Regarding modalities (channels) of change, classroom-based programs showed the highest quit rates (17%). Computer-based (expert system) programs also showed promise (13% quit-rate), as did school-based clinics (12%). There was a fair amount of missing data and wide variation on how data points were measured in the programs' evaluations. Also, there were relatively few direct comparisons of program and control groups. Thus, it would be difficult to conduct a formal meta-analysis on the cessation programs. Still, these data suggest that use of adolescent tobacco use cessation interventions double quit rates on the average. In the 17 self-initiated quitting survey studies, key predictors of quitting were living in a social milieu that is composed of fewer smokers, less pharmacological or psychological dependence on smoking, anti-tobacco beliefs (e.g., that society should step in to place controls on smoking) and feeling relatively hopeful about life. Key variables relevant to the quitting process may include structuring the context of programming for youth, motivating quit attempts and reducing ambivalence about quitting, and making programming enjoyable as possible. There also is a need to help youth to sustain a quit-attempt. In this regard, one could provide ongoing support during the acute withdrawal period and teach youth social/life skills. Since there is little information currently available on use of nicotine replacement in young people, continued research in this arena might also be a useful focus for future work.
Final report on APMP.T-K7.1 key comparison of water triple point cells, bilateral NMIJ-VMI
NASA Astrophysics Data System (ADS)
Yamazawa, Kazuaki; Nakano, Tohru; Thanh Binh, Pham
2018-01-01
APMP.T-K7.1, was held from July 2014 to May 2015 to compare the national realizations of the water triple point between NMIJ (Japan) and VMI (Vietnam). To reach the objective, VMI sent a transfer cell to NMIJ and stated a value for the temperature difference of the transfer cell, relative to the corresponding national standard, representing 273.16 K. This report presents the results of the TPW comparison, gives detailed information about the measurements made at the NMIJ and at the VMI, and aims to link the results of APMP.T-K7.1 to APMP.T-K7 and CCT-K7. The results of this key comparison are also represented in the form of degrees of equivalence for the purposes of the MRA. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Vascular nutritional correlates of late-life depression.
Payne, Martha E; Hybels, Celia F; Bales, Connie W; Steffens, David C
2006-09-01
The authors sought to examine the association of vascular nutritional factors and depression in an elderly cohort of depression (currently and recently depressed) and comparison (never depressed) subjects. Nutrient intake over the past year was assessed in 196 elderly depression and comparison individuals with a Block 1998 food-frequency questionnaire. Nutrient intake, body mass index, and Keys score (a measure of the serum cholesterol-raising capacity of the diet) were determined. Subjects were age 60 and over and were participants in a longitudinal study of major depression. All subjects received psychiatric and medical comorbidity assessments; depression subjects also received psychiatric treatment. Vascular nutritional factors differed between depression and comparison subjects. The depression group had higher intake of saturated fat and cholesterol, higher body mass indices, lower alcohol intake, and higher Keys score than the comparison group. After controlling for age, sex, education, race, and medical comorbidity, associations remained for cholesterol, alcohol, and Keys score. Depression was found to be associated with overall dietary pattern as defined by total kilocalories, saturated fat, cholesterol, body mass index, polyunsaturated fat, sodium, and alcohol. This study provides evidence that dietary vascular risk factors differ in individuals with current or prior depression when compared with individuals with no history of depression.
Ku, Pei-Yun; Lee, Robert Kuo-Kuang; Lin, Shyr-Yeu; Lin, Ming-Huei; Hwu, Yuh-Ming
2012-12-01
To compare the clinical outcomes between fresh and vitrified-thawed day 5 blastocyst transfers. Retrospective case control study. Tertiary referral center. Patients 38 years of age or less who underwent IVF/ICSI cycles with fresh or frozen-thawed blastocysts transferred from June 1, 2009 to November 30, 2011 Vitrification and thawing of day 5 blastocysts using the Cryotop method. (Kitazato BioPharma Co., Ltd., Fuji city, Shizuoka, Japan) Clinical pregnancy rate, implantation rate, ongoing pregnancy rate, and multiple pregnancy rates. Of the 118 cycles in the fresh transfer group, 234 blastocysts were transferred. The clinical pregnancy rate was 66.1 % and implantation rate was 50.9 %. The ongoing pregnancy rate was 56.8 % and the rates for singleton and twin pregnancies were 53.7 % and 44.8 %. Of the 59 cycles in the vitrified-thawed group, 111 blastocysts were transferred. The clinical pregnancy rate was 59.3 % and implantation rate was 43.2 %. The ongoing pregnancy rate was 47.5 % and the rates for singleton and twin pregnancies were 60.7 % and 39.3 %. The clinical pregnancy rate, implantation rate and ongoing pregnancy rate did not differ significantly between the two groups. The implantation rates were not significantly different between the fresh and the vitrified-thawed groups. Thus, single embryo transfer may be considered in fresh cycles to decrease multiple pregnancy rates. The surplus embryos should be vitrified for the frozen embryo transfer to improve the cumulative pregnancy rate.
Modeling a space-based quantum link that includes an adaptive optics system
NASA Astrophysics Data System (ADS)
Duchane, Alexander W.; Hodson, Douglas D.; Mailloux, Logan O.
2017-10-01
Quantum Key Distribution uses optical pulses to generate shared random bit strings between two locations. If a high percentage of the optical pulses are comprised of single photons, then the statistical nature of light and information theory can be used to generate secure shared random bit strings which can then be converted to keys for encryption systems. When these keys are incorporated along with symmetric encryption techniques such as a one-time pad, then this method of key generation and encryption is resistant to future advances in quantum computing which will significantly degrade the effectiveness of current asymmetric key sharing techniques. This research first reviews the transition of Quantum Key Distribution free-space experiments from the laboratory environment to field experiments, and finally, ongoing space experiments. Next, a propagation model for an optical pulse from low-earth orbit to ground and the effects of turbulence on the transmitted optical pulse is described. An Adaptive Optics system is modeled to correct for the aberrations caused by the atmosphere. The long-term point spread function of the completed low-earth orbit to ground optical system is explored in the results section. Finally, the impact of this optical system and its point spread function on an overall quantum key distribution system as well as the future work necessary to show this impact is described.
KEY COMPARISON: Final report of EUROMET Project 696: pH determination of a phthalate buffer
NASA Astrophysics Data System (ADS)
Spitzer, Petra; Charlet, Philippe; Eberhard, Ralf; Karpov, Oleg V.; Philippe, Rachel; Rivier, Cedric; Maximov, Igor; Sudmeier, Uwe
2005-01-01
The EUROMET project 696, a trilateral comparison between PTB, Germany, LNE, France and VNIIFTRI, Russia was performed in order to demonstrate and document the capability of the participants to measure the pH of a phthalate buffer by the primary measurement procedure for pH. Good agreement of the reported results was observed. The sample was very similar to the one used in the comparison CCQM-K17. PTB acts as pilot laboratory in CCQM-K17 and in EUROMET 696. This comparison allows one to link the results obtained by LNE to the CCQM-K17 key comparison through the degree of equivalence of PTB. On the other hand, the discrepancy between measured pH values at the VNIIFTRI and PTB for the same type of buffer solution decreased, as compared with a bilateral comparison in 1997. Main text. To reach the main text of this paper, click on Final Report. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the Mutual Recognition Arrangement (MRA).
Operating Reserves and Wind Power Integration: An International Comparison; Preprint
DOE Office of Scientific and Technical Information (OSTI.GOV)
Milligan, M.; Donohoo, P.; Lew, D.
2010-10-01
This paper provides a high-level international comparison of methods and key results from both operating practice and integration analysis, based on an informal International Energy Agency Task 25: Large-scale Wind Integration.
Highlights of Transient Plume Impingement Model Validation and Applications
NASA Technical Reports Server (NTRS)
Woronowicz, Michael
2011-01-01
This paper describes highlights of an ongoing validation effort conducted to assess the viability of applying a set of analytic point source transient free molecule equations to model behavior ranging from molecular effusion to rocket plumes. The validation effort includes encouraging comparisons to both steady and transient studies involving experimental data and direct simulation Monte Carlo results. Finally, this model is applied to describe features of two exotic transient scenarios involving NASA Goddard Space Flight Center satellite programs.
Status of indium phosphide solar cell development at Spire
NASA Technical Reports Server (NTRS)
Spitzer, M. B.; Keavney, C. J.; Vernon, S. M.
1987-01-01
On-going development of indium phosphide solar cells for space applications is presented. The development is being carried out with a view towards both high conversion efficiency and simplicity of manufacture. The cell designs comprise the ion-implanted cell, the indium tin oxide top contact cell, and the epitaxial cell grown by metal organic chemical vapor deposition. Modelling data on the limit to the efficiency are presented and comparison is made to measured performance data.
Erpenbeck, Dirk; Knowlton, Anne L.; Talbot, Sandra L.; Highsmith, Ray C.; van Soest, Rob W.M.
2004-01-01
The intraspecific relationships between populations of Alaskan Halichondria cf. panicea are the subjects of ongoing research. In this study we compare CO1 sequences of Alaskan Halichondria cf. panicea with North East Atlantic Halichondria panicea and its sister species Halichondria bowerbanki. Alaskan Halichondria cf. panicea form a well-supported sister group to the European Halichondria panicea/ H. bowerbanki species complex in the resulting gene tree and cluster distantly from their European conspecifics.
2006-09-30
DRDC-A, and the NATO Undersea Research Centre, La Spezia Italy (this is ongoing). Under these main topics, accomplishments included: a...associated with clutter from an undersea ridge and mud volcano cluster. RESULTS A constrained comparison of waveguide reverberation theory and...1000 Hz c) 0 10 20 −70 −60 −50 −40 −30 −20 −10 Angle (deg) S ca tte rin g S tr en gt h (d B ) 900 Hz a) Figure 1. Measured (x) seabed a
Ovayolu, Ali; Arslanbuğa, Cansev Yilmaz; Gun, Ismet; Devranoglu, Belgin; Ozdemir, Arman; Cakar, Sule Eren
2016-01-01
Objective: To determine whether semen and plasma presepsin values measured in men with normozoospermia and oligoasthenospermia undergoing invitro-fertilization would be helpful in predicting ongoing pregnancy and live birth. Methods: Group-I was defined as patients who had pregnancy after treatment and Group-II comprised those with no pregnancy. Semen and blood presepsin values were subsequently compared between the groups. Parametric comparisons were performed using Student’s t-test, and non-parametric comparisons were conducted using the Mann-Whitney U test. Results: There were 42 patients in Group-I and 72 in Group-II. In the context of successful pregnancy and live birth, semen presepsin values were statistically significantly higher in Group-I than in Group-II (p= 0.004 and p= 0.037, respectively). The most appropriate semen presepsin cut-off value for predicting both ongoing pregnancy and live birth was calculated as 199 pg/mL. Accordingly, their sensitivity was 64.5% to 59.3%, their specificity was 57.0% to 54.2%, and their positive predictive value was 37.0% to 29.6%, respectively; their negative predictive value was 80.4% in both instances. Conclusion: Semen presepsin values could be a new marker that may enable the prediction of successful pregnancy and/or live birth. Its negative predictive values are especially high. PMID:27882005
Regional comparison of absolute gravimeters, EURAMET.M.G-K2 key comparison
NASA Astrophysics Data System (ADS)
Pálinkáš, V.; Francis, O.; Val'ko, M.; Kostelecký, J.; Van Camp, M.; Castelein, S.; Bilker-Koivula, M.; Näränen, J.; Lothhammer, A.; Falk, R.; Schilling, M.; Timmen, L.; Iacovone, D.; Baccaro, F.; Germak, A.; Biolcati, E.; Origlia, C.; Greco, F.; Pistorio, A.; De Plaen, R.; Klein, G.; Seil, M.; Radinovic, R.; Reudink, R.; Dykowski, P.; Sȩkowski, M.; Próchniewicz, D.; Szpunar, R.; Mojzeš, M.; Jańk, J.; Papčo, J.; Engfeldt, A.; Olsson, P. A.; Smith, V.; van Westrum, D.; Ellis, B.; Lucero, B.
2017-01-01
In the framework of the regional EURAMET.M.G-K2 comparison of absolute gravimeters, 17 gravimeters were compared in November 2015. Four gravimeters were from different NMIs and DIs, they were used to link the regional comparison to the CCM.G.K2 by means of linking converter. Combined least-squares adjustments with weighted constraint was used to determine KCRV. Several pilot solutions are presented and compared with the official solution to demonstrate influences of different approaches (e.g. definition of weights and the constraint) on results of the adjustment. In case of the official solution, all the gravimeters are in equivalence with declared uncertainties. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
NASA Astrophysics Data System (ADS)
Michotte, C.; Courte, S.; Ratel, G.; Moune, M.; Johansson, L.; Keightley, J.
2010-01-01
In 2007 and 2008 respectively, the Laboratoire national de métrologie et d'essais-Laboratoire national Henri Becquerel (LNE-LNHB), France and the National Physical Laboratory (NPL), UK, submitted ampoules with between 10 MBq and 130 MBq activity of 99mTc to the International Reference System (SIR), to update their results in the BIPM.RI(II)-K1.Tc-99m comparison. Together with the four other national metrology institutes (NMI) that are participants, thirteen samples have been submitted since 1983. The key comparison reference value (KCRV) has been recalculated to include the latest primary results of the PTB and the LNE-LNHB as this makes the evaluation more robust. The degrees of equivalence between each equivalent activity measured in the SIR are given in the form of a matrix for all six NMIs. A graphical presentation is also given. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCRI Section II, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
Final report on international comparison CCQM-K83: Halocarbons in dry whole air
NASA Astrophysics Data System (ADS)
Rhoderick, George; Guenther, Franklin; Duewer, David; Lee, Jeongsoon; Moon, Dongmin; Lee, Jinbok; Lim, Jeongsik; Seog Kim, Jin
2014-01-01
The growing awareness of climate change/global warming and continuing concerns regarding stratospheric ozone depletion will require future measurements and standards for many compounds, in particular halocarbons that are linked to these issues. In order to track and control the emissions of these species globally in the atmosphere, it is necessary to demonstrate measurement equivalence at the highest levels of accuracy for assigned values of standards. This report describes the results of a key comparison for several of the more important halocarbons at atmospheric concentration levels. The comparison includes the chlorofluorocarbons (CFCs) dichlorodifluoromethane (CFC 12), trichlorofluoromethane (CFC 11), and 1,1,2 trichlorotrifluoroethane (CFC 113); the hydrochlorofluorocarbons (HCFCs) chlorodifluoromethane (HCFC 22) and 1-chloro-1,1-difluoroethane (HCFC 142b); and the hydrofluorocarbon (HFC) 1,1,1,2 tetrafluoroethane (HFC 134a), all in a dried whole air sample. The objective of this key comparison is to compare the measurement capabilities of the participants for these halocarbons at trace atmospheric levels. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Berlin, Jesse A; Cepeda, M Soledad
2012-02-01
The purpose of comparative effectiveness research (CER) is to assist consumers, clinicians, purchasers, and policy makers to make informed decisions that will improve health care at both the individual and population levels. There is an ongoing discussion as to what types of evidence are appropriate to inform CER and how best to interpret various forms of evidence. The purpose of this article is primarily to highlight several interesting methodological issues in the conduct of CER reviews. We describe several key challenges related to randomized trials, with a particular focus on noninferiority studies, which include active comparators used to assess 'assay sensitivity' (defined below), and on the use of randomized studies to perform indirect comparisons between therapies. We touch briefly on the use of observational studies in CER, particularly because of the importance of observational studies in assessing infrequently occurring harms. We argue that studies that may be perceived as unsuitable to address some CER questions may well be appropriate to address others. As an example, noninferiority studies (assuming they include an appropriate comparator at an appropriate dose), are sometimes discounted or excluded from consideration because of concerns that the sponsor's incentive is to conduct a study that is biased toward showing no difference between the treatment groups. If the purpose of a systematic review of CER is to show superiority with respect to a purported benefit, including studies that may be biased toward equality of treatments would tend to underestimate the proposed benefit, that is, the bias works against the sponsor. This is not a comprehensive review of all methodological issues related to CER, and we recognize that there may be dissenting opinions regarding some of the points we raise. In considering the use of systematic reviews, we believe it is sound advice to perform the head-to-head comparison when possible, in the relevant populations, using endpoints relevant to patients, caregivers, physicians, or payers. These endpoints should include patient-reported outcomes (e.g., symptoms), when relevant. Indirect comparisons and mixed treatment meta-analyses may be useful for simultaneously comparing multiple treatments, provided the assumptions underlying such analyses are plausible.
NASA Astrophysics Data System (ADS)
Driver, R. Gregory; Olson, Douglas A.; Dilawar, Nita; Bandyopadhyay, A. K.
2007-01-01
We report the results of a bilateral comparison of pressure measurement between NIST and NPLI using a piston gauge transfer standard (TS), designated as NPLI-4, over the range of nominal applied pressure 0.4 MPa to 4.0 MPa. This TS was cross-floated against the laboratory secondary standard designated as PG13 at NIST, USA and against NPLI-8 at NPLI, India. The nominal pressure points of the bilateral comparison were (0.4, 0.8, 1.2, 1.6, 2.0, 2.4, 2.8, 3.2, 3.6 and 4.0) MPa, respectively. The comparison was performed in both the institutes in identical pressure cycles in increasing pressures. The comparison data were analysed in terms of the effective area [Ap (mm2)] as a function pressure [p (MPa)] of the TS at the above-mentioned pressures. We have also estimated the zero-pressure effective area [A0 (mm2)] and the pressure distortion coefficient [λ (MPa-1)] of the transfer standard. The consistency of the results at every pressure in the range indicates that the laboratory standards used in this comparison are compatible, uniform and can be considered traceable to each other. Finally, the degree of equivalence between NPLI and NIST is 11.4 × 10-6 or better, which is always less than the relative standard uncertainty of the difference (33.6 × 10-6). Main text. To reach the main text of this Paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
Ecological assessment of nano-enabled supercapacitors for automotive applications
NASA Astrophysics Data System (ADS)
Weil, M.; Dura, H.; Shimon, B.; Baumann, M.; Zimmermann, B.; Ziemann, S.; Lei, C.; Markoulidis, F.; Lekakou, T.; Decker, M.
2012-09-01
New materials on nano scale have the potential to overcome existing technical barriers and are one of the most promising key technologies to enable the decoupling of economic growth and resource consumption. Developing these innovative materials for industrial applications means facing a complex quality profile, which includes among others technical, economic, and ecological aspects. So far the two latter aspects are not sufficiently included in technology development, especially from a life cycle point of view. Supercapacitors are considered a promising option for electric energy storage in hybrid and full electric cars. In comparison with presently used lithium based electro chemical storage systems supercapacitors possess a high specific power, but a relatively low specific energy. Therefore, the goal of ongoing research is to develop a new generation of supercapacitors with high specific power and high specific energy. To reach this goal particularly nano materials are developed and tested on cell level. In the presented study the ecological implications (regarding known environmental effects) of carbon based nano materials are analysed using Life Cycle Assessment (LCA). Major attention is paid to efficiency gains of nano particle production due to scaling up of such processes from laboratory to industrial production scales. Furthermore, a developed approach will be displayed, how to assess the environmental impact of nano materials on an automotive system level over the whole life cycle.
Polyimide-Epoxy Composites with Superior Bendable Properties for Application in Flexible Electronics
NASA Astrophysics Data System (ADS)
Lee, Sangyoup; Yoo, Taewon; Han, Youngyu; Kim, Hanglim; Han, Haksoo
2017-08-01
The need for flexible electronics with outstanding bending properties is increasing due to the demand for wearable devices and next-generation flexible or rollable smartphones. In addition, the requirements for flexible or rigid-flexible electronics are sharply increasing to achieve the design of space-saving electronic devices. In this regard, coverlay (CL) film is a key material used in the bending area of flexible electronics, albeit infrequently. Because flexible electronics undergo folding and unfolding numerous times, CL films with superior mechanical and bending properties are required so that the bending area can endure such severe stress. However, because current CL films are only used for a designated bending area in the flexible electronics panel, their highly complicated and expensive manufacturing procedure is a disadvantage. In addition, the thickness of CL films must be decreased to satisfy the ongoing requirement for increasingly thin products. However, due to the limitations of the two-layer structure of existing CL films, the manufacturing process cannot be made more cost effective by simply applying more thin film onto the board. To address this problem, we have developed liquid coverlay inks (LCIs) with superior bendable properties, in comparison with CL films, when applied onto flexible electronics using a screen-printing method. The results show that LCIs have the potential to become one of the leading candidates to replace existing CL films because of their lower cost and faster manufacturing process.
DOE Office of Scientific and Technical Information (OSTI.GOV)
Kreutzer, Cory J.; Rugh, John; Tomerlin, Jeff
Increased market penetration of electric drive vehicles (EDVs) requires overcoming a number of hurdles, including limited vehicle range and the elevated cost in comparison to conventional vehicles. Climate control loads have a significant impact on range, cutting it by over 50% in both cooling and heating conditions. To minimize the impact of climate control on EDV range, the National Renewable Energy Laboratory has partnered with Hyundai America and key industry partners to quantify the performance of thermal load reduction technologies on a Hyundai Sonata plug-in hybrid electric vehicle. Technologies that impact vehicle cabin heating in cold weather conditions and cabinmore » cooling in warm weather conditions were evaluated. Tests included thermal transient and steady-state periods for all technologies, including the development of a new test methodology to evaluate the performance of occupant thermal conditioning. Heated surfaces demonstrated significant reductions in energy use from steady-state heating, including a 29%-59% reduction from heated surfaces. Solar control glass packages demonstrated significant reductions in energy use for both transient and steady-state cooling, with up to a 42% reduction in transient and 12.8% reduction in steady-state energy use for the packages evaluated. Technologies that demonstrated significant climate control load reduction were selected for incorporation into a complete thermal load reduction package. The complete package is set to be evaluated in the second phase of the ongoing project.« less
Politi, Eirini; Rowan, John S; Cutler, Mark E J
2016-02-01
Over 50% of the world's population live within 3 km of rivers and lakes highlighting the on-going importance of freshwater resources to human health and societal well-being. Whilst covering c. 3.5% of the Earth's non-glaciated land mass, trends in the environmental quality of the world's standing waters (natural lakes and reservoirs) are poorly understood, at least in comparison with rivers, and so evaluation of their current condition and sensitivity to change are global priorities. Here it is argued that a geospatial approach harnessing existing global datasets, along with new generation remote sensing products, offers the basis to characterise trajectories of change in lake properties e.g., water quality, physical structure, hydrological regime and ecological behaviour. This approach furthermore provides the evidence base to understand the relative importance of climatic forcing and/or changing catchment processes, e.g. land cover and soil moisture data, which coupled with climate data provide the basis to model regional water balance and runoff estimates over time. Using examples derived primarily from the Danube Basin but also other parts of the World, we demonstrate the power of the approach and its utility to assess the sensitivity of lake systems to environmental change, and hence better manage these key resources in the future. Copyright © 2015 The Authors. Published by Elsevier B.V. All rights reserved.
Heller, Martin C; Keoleian, Gregory A; Willett, Walter C
2013-11-19
Supplying adequate human nutrition within ecosystem carrying capacities is a key element in the global environmental sustainability challenge. Life cycle assessment (LCA) has been used effectively to evaluate the environmental impacts of food production value chains and to identify opportunities for targeted improvement strategies. Dietary choices and resulting consumption patterns are the drivers of production, however, and a consumption-oriented life cycle perspective is useful in understanding the environmental implications of diet choices. This review identifies 32 studies that use an LCA framework to evaluate the environmental impact of diets or meals. It highlights the state of the art, emerging methodological trends and current challenges and limitations to such diet-level LCA studies. A wide range of bases for analysis and comparison (i.e., functional units) have been employed in LCAs of foods and diet; we conceptually map appropriate functional unit choices to research aims and scope and argue for a need to move in the direction of a more sophisticated and comprehensive nutritional basis in order to link nutritional health and environmental objectives. Nutritional quality indices are reviewed as potential approaches, but refinement through ongoing collaborative research between environmental and nutritional sciences is necessary. Additional research needs include development of regionally specific life cycle inventory databases for food and agriculture and expansion of the scope of assessments beyond the current focus on greenhouse gas emissions.
Bullock, A D; Barnes, E; Falcon, H C; Stearns, K
2013-04-01
Focused on the dental therapists foundation training (TFT) scheme run by the Postgraduate Dental Deaneries of Oxford and Wessex (NHS Education South Central - NESC) the objectives were (1) to evaluate the TFT 2010/11 scheme, identifying strengths, areas for development and drawing comparisons with the 2009 evaluation; and (2) to follow-up previous cohorts, reporting current work and retrospective reflections on the scheme. Data were collected from 2010/11 ('current') trainees (n = 10) through group discussion, questionnaire and portfolio extracts. Eleven past-trainees from 2008/09 and 2009/10 took part in a structured telephone interview or responded to questions via e-mail. Data from 2011 consolidated that collected earlier. The scheme was highly valued. Current participants thought the scheme should be mandatory and all past-participants would recommend it to others. Trainees attributed an increase in confidence and ability in their clinical skills to participation in TFT. Current trainees' concerns about finding therapy work were echoed in past-participants' post-scheme employment. At the point of qualification, trainees do not feel well-prepared for starting work as dental therapists. Opportunity to develop confidence and skills in a supportive environment is a key benefit of the scheme. Maintaining ability in the full range of duties requires continued use of skills and the opportunity to do this remains an ongoing challenge.
Yip, Marcus J.; Porter, Jessica L.; Fyfe, Janet A. M.; Lavender, Caroline J.; Portaels, Françoise; Rhodes, Martha; Kator, Howard; Colorni, Angelo; Jenkin, Grant A.; Stinear, Tim
2007-01-01
It had been assumed that production of the cytotoxic polyketide mycolactone was strictly associated with Mycobacterium ulcerans, the causative agent of Buruli ulcer. However, a recent study has uncovered a broader distribution of mycolactone-producing mycobacteria (MPM) that includes mycobacteria cultured from diseased fish and frogs in the United States and from diseased fish in the Red and Mediterranean Seas. All of these mycobacteria contain versions of the M. ulcerans pMUM plasmid, produce mycolactones, and show a high degree of genetic relatedness to both M. ulcerans and Mycobacterium marinum. Here, we show by multiple genetic methods, including multilocus sequence analysis and DNA-DNA hybridization, that all MPM have evolved from a common M. marinum progenitor to form a genetically cohesive group among a more diverse assemblage of M. marinum strains. Like M. ulcerans, the fish and frog MPM show multiple copies of the insertion sequence IS2404. Comparisons of pMUM and chromosomal gene sequences demonstrate that plasmid acquisition and the subsequent ability to produce mycolactone were probably the key drivers of speciation. Ongoing evolution among MPM has since produced at least two genetically distinct ecotypes that can be broadly divided into those typically causing disease in ectotherms (but also having a high zoonotic potential) and those causing disease in endotherms, such as humans. PMID:17172337
6. September 1971 DETAIL VIEW OF CHAIN PADLOCK AND KEY ...
6. September 1971 DETAIL VIEW OF CHAIN PADLOCK AND KEY TO SECURE DOOR TO MAIN CELL BLOCK, NOTE STANDARD MODERN PADLOCK FOR SIZE COMPARISON - Jefferson County Jail & Sheriff's Office, Courthouse Square, Madison, Jefferson County, IN
NASA Astrophysics Data System (ADS)
Vals, M.
2017-09-01
We use MAVEN/NGIMS CO2 density measurements to analyse gravity waves in the thermosphere of Mars. In particular the seasonal/latitudinal variability of their amplitude is studied and interpreted. Key background parameters controlling the activity of gravity waves are analysed with the help of the Mars Climate Database (MCD). Gravity waves activity presents a good anti-correlation to the temperature variability retrieved from the MCD. An analysis at pressure levels is ongoing.
The application of nanotechnology in medicine: treatment and diagnostics.
Owen, Andrew; Dufès, Christine; Moscatelli, Davide; Mayes, Eric; Lovell, Jonathan F; Katti, Kattesh V; Sokolov, Konstantin; Mazza, Mariarosa; Fontaine, Olivier; Rannard, Steve; Stone, Vicki
2014-07-01
Nanomedicine 2014 Edinburgh, UK, 26-27 March 2014 The British Society for Nanomedicine (BSNM), in collaboration with SELECTBIO, organized Nanomedicine 2014. BSNM is a registered charity created to allow open access for industry, academia, clinicians and the public to news and details of ongoing nanomedicine research. The Nanomedicine 2014 program provided insight across a number of emerging nanotechnologies spanning treatment to diagnostics. A key objective of the meeting was provision of opportunities to build collaborations and rationalize nanoenabled healthcare solutions.
Havill, Nancy L
2013-05-01
Because increasing evidence suggests that the environment plays a role in transmission of health care-associated infections, more attention is focusing on environmental cleaning and improving its efficacy. Creating and sustaining a successful cleaning and disinfection program should include several key components using a bundle approach and requires ongoing commitment within the institution. Copyright © 2013 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.
Veresoglou, Stavros D.; Halley, John M.; Rillig, Matthias C.
2015-01-01
No species lives on earth forever. Knowing when and why species go extinct is crucial for a complete understanding of the consequences of anthropogenic activity, and its impact on ecosystem functioning. Even though soil biota play a key role in maintaining the functioning of ecosystems, the vast majority of existing studies focus on aboveground organisms. Many questions about the fate of belowground organisms remain open, so the combined effort of theorists and applied ecologists is needed in the ongoing development of soil extinction ecology. PMID:26593272
Cybersecurity in Artificial Pancreas Experiments.
O'Keeffe, Derek T; Maraka, Spyridoula; Basu, Ananda; Keith-Hynes, Patrick; Kudva, Yogish C
2015-09-01
Medical devices have transformed modern health care, and ongoing experimental medical technology trials (such as the artificial pancreas) have the potential to significantly improve the treatment of several chronic conditions, including diabetes mellitus. However, we suggest that, to date, the essential concept of cybersecurity has not been adequately addressed in this field. This article discusses several key issues of cybersecurity in medical devices and proposes some solutions. In addition, it outlines the current requirements and efforts of regulatory agencies to increase awareness of this topic and to improve cybersecurity.
Command Control Group Behaviors. Objective 2. Command Control Training with Simulations
1984-08-01
made to Fort Leavenworth to obtain background information on simulation activities and2 usage, ARTEPs, and other related Army activities such as C SPR...Year Three, with the various volumes focusing on one or more key aspects of training with simulations. 1.5 RELATED ACTIVITIES As the research of Year...One was being conducted, it became apparent that a number of on-going Army activities may impact the final pr3duct and therefore have been, and
2017-04-01
from contractors . Until Block 3F testing is complete, DOD will not have the knowledge it needs to present a sound business case for Block 4. Second...January 2017 the details of this plan were unclear because DOD’s 2018 budget was not final and negotiations with the contractors were ongoing...management reports and historical test data; discussed key aspects of F-35 development with program management and contractor officials; and compared
Quantum key distribution with finite resources: Secret key rates via Renyi entropies
DOE Office of Scientific and Technical Information (OSTI.GOV)
Abruzzo, Silvestre; Kampermann, Hermann; Mertz, Markus
A realistic quantum key distribution (QKD) protocol necessarily deals with finite resources, such as the number of signals exchanged by the two parties. We derive a bound on the secret key rate which is expressed as an optimization problem over Renyi entropies. Under the assumption of collective attacks by an eavesdropper, a computable estimate of our bound for the six-state protocol is provided. This bound leads to improved key rates in comparison to previous results.
NASA Astrophysics Data System (ADS)
Goenaga Infante, Heidi; Sargent, Mike
2010-01-01
Key comparison CCQM-K60 was performed to assess the analytical capabilities of national metrology institutes (NMIs) to accurately quantitate the mass fraction of selenomethionine (SeMet) and total selenium (at low mg kg-1 levels) in selenised wheat flour. It was organized by the Inorganic Analysis Working Group (IAWG) of the Comité Consultatif pour la Quantité de Matière (CCQM) as a follow-up key comparison to the previous pilot study CCQM-P86 on selenised yeast tablets. LGC Limited (Teddington, UK) and the Institute for National Measurement Standards, National Research Council Canada (NRCC, Ottawa, Canada) acted as the coordinating laboratories. CCQM-K60 was organized in parallel with a pilot study (CCQM-P86.1) involving not only NMIs but also expert laboratories worldwide, thus enabling them to assess their capabilities, discover problems and learn how to modify analytical procedures accordingly. Nine results for total Se and four results for SeMet were reported by the participant NMIs. Methods used for sample preparation were microwave assisted acid digestion for total Se and multiple-step enzymatic hydrolysis and hydrolysis with methanesulfonic acid for SeMet. For total Se, detection techniques included inductively coupled plasma mass spectrometry (ICP-MS) with external calibration, standard additions or isotope dilution analysis (IDMS); instrumental neutron activation analysis (INAA); and graphite furnace atomic absorption spectrometry (GFAAS) with external calibration. For determination of SeMet in the wheat flour sample, the four NMIs relied upon measurements using species-specific IDMS (using 76Se-enriched SeMet) with HPLC-ICP-MS. Eight of the nine participating NMIs reported results for total Se within 3.5% deviation from the key comparison reference value (KCRV). For SeMet, the four participating NMIs reported results within 3.2% deviation from the KCRV. This shows that the performance of the majority of the CCQM-K60 participants was very good, illustrating their ability to obtain accurate results for such analytes in a complex food matrix containing approximately 17 mg kg-1 Se. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (MRA).
Final report on the torque key komparison CCM.T-K1.2 measurand torque: 0 N.m, 500 N.m, 1000 N.m
NASA Astrophysics Data System (ADS)
Röske, Dirk
2015-01-01
The purpose of the CIPM subsequent bilateral comparison CCM.T-K1.2 was to link another participant, namely the National Institute of Metrology (Thailand), in short NIMT, to the CCM.T-K1 torque key comparison. The measuring capabilities up to 1000 N.m of dead-weight torque standard machines with supported lever were investigated. The pilot laboratory was the same in both comparisons—it was the Physikalisch-Technische Bundesanstalt (PTB, Braunschweig, Germany). The same two very stable torque transducers with well-known properties were used as travelling standards. The measurements at the participating laboratory were carried out between November 2007 and February 2008. According to the technical protocol, torque steps of 500 N.m and 1000 N.m had to be measured both in clockwise and anticlockwise directions. Corrections had to be applied to the results reported by the participants taking into account the use of different amplifiers, the creep (due to different loading times of the machines) and the environmental conditions in the laboratories (temperature and relative humidity of the ambient air). The results of the pilot laboratory in this bilateral comparison are in very good agreement with the same results obtained in the CCM.T-K1 comparison. For each of the transducers, the two torque steps and both senses of direction of the torque vector, the key comparison reference value of the CCM.T-K1 was taken, and the results of participant NIMT were calculated with respect to these values. The agreement between the results is very good. The smallest expanded (k = 2) relative uncertainty of the machine stated by the participant is 1 × 10-4. The results of the comparison support this uncertainty statement. Main text. To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by CCM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
ClinicalKey: a point-of-care search engine.
Vardell, Emily
2013-01-01
ClinicalKey is a new point-of-care resource for health care professionals. Through controlled vocabulary, ClinicalKey offers a cross section of resources on diseases and procedures, from journals to e-books and practice guidelines to patient education. A sample search was conducted to demonstrate the features of the database, and a comparison with similar tools is presented.
Key Elements of a Good Mathematics Lesson as Seen by Japanese Junior High School Teachers
ERIC Educational Resources Information Center
Ebaeguin, Marlon; Stephens, Max
2016-01-01
This study makes a comparison between what literature on Japanese Lesson Study suggests are key elements of a good mathematics lesson and what junior high school mathematics teachers in Japan value in planning their lessons. The teachers' strong consensus in their endorsements of these key elements explains why Japanese teachers strongly support…