Organizing for Reporting.

ERIC Educational Resources Information Center

Wilton, Jennifer

1990-01-01

Reporting occupies a central place in institutional research but is ongoing and never completed. With automation and data management, the proportion of time spent on either routine or ad hoc reporting should decline. This function need not draw unnecessarily from resources for more interesting work. (MSE)

The Comprehension of Rapid Speech by the Blind: Part III. Final Report.

ERIC Educational Resources Information Center

Foulke, Emerson

Accounts of completed and ongoing research conducted from 1964 to 1968 are presented on the subject of accelerated speech as a substitute for the written word. Included are a review of the research on intelligibility and comprehension of accelerated speech, some methods for controlling the word rate of recorded speech, and a comparison of…

The Colorado Front Range Ecosystem Management Research Project: Accomplishments to date

Treesearch

Brian Kent; Wayne D. Shepperd; Deborah J. Shields

2000-01-01

This article briefly describes the goals and objectives for the Colorado Front Range Ecosystem Management Project (FREM). Research under this project has addressed both biophysical and human dimensions problems relating to ecosystem management in the Colorado Front Range. Results of completed work are described, and the status of the ongoing demonstration project at...

Understanding the Psychological Contract in Apprenticeships and Traineeships to Improve Retention. Research Report

ERIC Educational Resources Information Center

Smith, Erica; Walker, Arlene; Kemmis, Ros Brennan

2011-01-01

Attrition in apprenticeships and traineeships is an ongoing concern for employers and government alike, with completion standing at around 50% on average. One possible explanation for this high attrition rate is that there is a mismatch between the respective expectations of apprentices/trainees and employers. This research uses the concept of the…

Insights from clinical research completed during the west Africa Ebola virus disease epidemic

PubMed Central

Rojek, Amanda; Horby, Peter; Dunning, Jake

2018-01-01

The west Africa Ebola virus disease (EVD) epidemic was extraordinary in scale. Now that the epidemic has ended, it is a relevant time to examine published studies with direct relevance to clinical care and, more broadly, to examine the implications of the clinical research response mounted. Clinically relevant research includes literature detailing risk factors for and clinical manifestations of EVD, laboratory and other investigation findings in patients, experimental vaccine and therapeutic clinical trials, and analyses of survivor syndrome. In this Review, we discuss new insights from patient-oriented research completed during the west Africa epidemic, identify ongoing knowledge gaps, and suggest priorities for future research. PMID:28461209

"There is One Geometry and in Each Case There is a Different Formula"

ERIC Educational Resources Information Center

Rizos, Ioannis; Patronis, Anastasios; Lappas, Dionyssios

2017-01-01

In this paper, we analyze two episodes from an inquiry-based didactical research; the complete analysis of our research data is still ongoing. By taking into consideration various developments from the history of the geometry of space-time, our general aim is to explore high school students' conceptions about measurement of length and time in…

Using Mental Imagery Processes for Teaching and Research in Mathematics and Computer Science

ERIC Educational Resources Information Center

Arnoux, Pierre; Finkel, Alain

2010-01-01

The role of mental representations in mathematics and computer science (for teaching or research) is often downplayed or even completely ignored. Using an ongoing work on the subject, we argue for a more systematic study and use of mental representations, to get an intuition of mathematical concepts, and also to understand and build proofs. We…

Ongoing child welfare services: Understanding the relationship of worker and organizational characteristics to service provision.

PubMed

Lwin, Kristen; Fluke, John; Trocmé, Nico; Fallon, Barbara; Mishna, Faye

2018-06-01

Ongoing child welfare services are put in place after completion of the initial maltreatment investigation when there is a perceived need to mitigate the risk of future harm. The knowledge of how clinical, worker, and organizational characteristics interact with this decision to provide ongoing child welfare services is not well integrated in the research literature. Using secondary data from the Canadian Incidence Study of Reported Child Abuse and Neglect-2008, this study's primary objective is to understand the relationship of clinical, worker, and organizational characteristics to the decision to transfer a case to ongoing child welfare services and their relative contribution to the transfer decision in Canada. Findings indicate that several clinical level variables are associated with families receiving ongoing services. Additionally, organizational factors, such as type of services offered by the organization and the number of employee support programs available to workers, significantly predicted the decision to transfer a case to ongoing services. While no worker factors, such as education, amount of training, experience, or caseload, were associated with ongoing service receipt, the intraclass correlation coefficient of the final three-level parsimonious model indicated substantial clustering at the worker level. Results indicate that Canadian child welfare workers make decisions differently based on factors not available in the current study and that what would be deemed as important worker characteristics do not necessarily predict this outcome. Findings and implications for future research are discussed. Copyright © 2018 Elsevier Ltd. All rights reserved.

The fate of completed intentions.

PubMed

Anderson, Francis T; Einstein, Gilles O

2017-04-01

The goal of this research was to determine whether and how people deactivate prospective memory (PM) intentions after they have been completed. One view proposes that PM intentions can be deactivated after completion, such that they no longer come to mind and interfere with current tasks. Another view is that now irrelevant completed PM intentions exhibit persisting activation, and continue to be retrieved. In Experiment 1, participants were given a PM intention embedded within the ongoing task during Phase 1, after which participants were told either that the PM task had been completed or suspended until later. During Phase 2, participants were instructed to perform only the ongoing task and were periodically prompted to report their thoughts. Critically, the PM targets from Phase 1 reappeared in Phase 2. All of our measures, including thoughts reported about the PM task, supported the existence of persisting activation. In Experiment 2, we varied conditions that were expected to mitigate persisting activation. Despite our best attempts to promote deactivation, we found evidence for the persistence of spontaneous retrieval in all groups after intentions were completed. The theoretical and practical implications of this potential dark side to spontaneous retrieval are discussed.

Powerful Practices in Digital Learning Processes

ERIC Educational Resources Information Center

Sørensen, Birgitte Holm; Levinsen, Karin Tweddell

2015-01-01

The present paper is based on two empirical research studies. The "Netbook 1:1" project (2009-2012), funded by the municipality of Gentofte and Microsoft Denmark, is complete, while "Students' digital production and students as learning designers" (2013-2015), funded by the Danish Ministry of Education, is ongoing. Both…

Research on Non-Lethal Stunning/Immobilizing Weapons

DTIC Science & Technology

2007-04-01

release, skeletal muscle contraction , on-line and real-time monitoring of bioeffects 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF 18. NUMBER 19a. NAME...and growth of on-going research projects in which non-thermal radiofrequency /microwave (RF/MW) effects on skeletal muscle contraction and...for studying nonthermal effects on skeletal muscle contraction . IEEE Transactions on Plasma Science, 34, 1470-1479. Thesis Bindya Dumpala completed

Energetic particles flux experiment for ISEE mother/daughter spacecraft

NASA Technical Reports Server (NTRS)

Anderson, K. A.

1981-01-01

The history of the energetic particle experiments on the International Sun Earth Explorer 1 and 2 spacecraft is outlined, and descriptions of the instruments are given. The inflight performance and data analysis are summarized. The research is completed and ongoing are described and a bibliography is included.

NCI International EBV-Gastric Cancer Consortium

Cancer.gov

A collaboration among NCI and extramural investigators, established by DCEG in 2006, that utilizes data and biospecimens from completed and ongoing case series and observational studies of gastric cancer to replicate and extend findings from previous studies hindered by small numbers of EBV-positive cases, and to stimulate multidisciplinary research in this area.

Prevalence of clinical trial status discrepancies: A cross-sectional study of 10,492 trials registered on both ClinicalTrials.gov and the European Union Clinical Trials Register.

PubMed

Fleminger, Jessica; Goldacre, Ben

2018-01-01

Trial registries are a key source of information for clinicians and researchers. While building OpenTrials, an open database of public trial information, we identified errors and omissions in registries, including discrepancies between descriptions of the same trial in different registries. We set out to ascertain the prevalence of discrepancies in trial completion status using a cohort of trials registered on both the European Union Clinical Trials Register (EUCTR) and ClinicalTrials.gov. We used matching titles and registry IDs provided by both registries to build a cohort of dual-registered trials. Completion statuses were compared; we calculated descriptive statistics on the prevalence of discrepancies. 11,988 dual-registered trials were identified. 1,496 did not provide a comparable completion status, leaving 10,492 trials. 16.2% were discrepant on completion status. The majority of discrepancies (90.5%) were a 'completed' trial on ClinicalTrials.gov inaccurately marked as 'ongoing' on EUCTR. Overall, 33.9% of dual-registered trials described as 'ongoing' on EUCTR were listed as 'completed' on ClinicalTrials.gov. Completion status on registries is commonly inaccurate. Previous work on publication bias may underestimate non-reporting. We describe simple steps registry owners and trialists could take to improve accuracy.

Learning during processing Word learning doesn’t wait for word recognition to finish

PubMed Central

Apfelbaum, Keith S.; McMurray, Bob

2017-01-01

Previous research on associative learning has uncovered detailed aspects of the process, including what types of things are learned, how they are learned, and where in the brain such learning occurs. However, perceptual processes, such as stimulus recognition and identification, take time to unfold. Previous studies of learning have not addressed when, during the course of these dynamic recognition processes, learned representations are formed and updated. If learned representations are formed and updated while recognition is ongoing, the result of learning may incorporate spurious, partial information. For example, during word recognition, words take time to be identified, and competing words are often active in parallel. If learning proceeds before this competition resolves, representations may be influenced by the preliminary activations present at the time of learning. In three experiments using word learning as a model domain, we provide evidence that learning reflects the ongoing dynamics of auditory and visual processing during a learning event. These results show that learning can occur before stimulus recognition processes are complete; learning does not wait for ongoing perceptual processing to complete. PMID:27471082

Spousal Coping Strategies in the Shadow of Terrorism.

PubMed

Shechory-Bitton, Mally; Cohen-Louck, Keren

2017-11-01

The present study focuses on spousal differences in reaction to ongoing exposure to terror and security threats. Sixty-eight married couples with children living in a region exposed to ongoing security threats were evaluated. All participants completed questionnaires on objective exposure (number of incidents) and subjective exposure (sense of fear) to terrorism and security threats, posttraumatic stress disorder (PTSD) symptoms, and their coping strategies with this ongoing exposure. Mothers reported higher levels of fear and PTSD symptoms, although their objective levels of exposure did not differ from those of their husbands. Similarities were found in coping strategies adopted by mothers and fathers to cope with life in the shadow of terrorism. Both mothers and fathers integrated emotion- and problem-focused coping strategies, with greater use of the latter. These similarities partially contradict research findings suggesting gender differences in coping with exposure to security threats. The results support the need for further research into investigating the role of dyadic coping in the context of prolonged exposure to security threats.

The role of temporal delay and repeated prospective memory cue exposure on the deactivation of completed intentions.

PubMed

Walser, Moritz; Plessow, Franziska; Goschke, Thomas; Fischer, Rico

2014-07-01

Previous studies have shown that completed prospective memory (PM) intentions entail aftereffects in terms of ongoing-task-performance decrements in trials containing repeated PM cues which previously served as PM cues triggering the intended action. Previous research reported that PM aftereffects decrease over time, thus revealing a specific time course of PM aftereffects. In the present study, we tested two accounts for this pattern, assuming either that the decline of aftereffects is related to the temporal distance to PM task completion or may be a result of the repeated exposure of repeated PM cues in the ongoing task. In three experiments, we manipulated both the temporal distance to PM task completion and the frequency of repeated PM cues and demonstrated that aftereffects of completed intentions declined with repeated exposure of formerly relevant PM cues. In addition, effects of repeated exposure were not only limited to the repetition of specific PM-cue exemplars but also generalized to other semantically related PM cues within the PM-cue category. Together, findings show that decreased aftereffects of completed intentions are not related to the temporal duration of the subsequent test block, but crucially depend on the repeated exposure of the previously relevant PM cues.

The audience eats more if a movie character keeps eating: An unconscious mechanism for media influence on eating behaviors.

PubMed

Zhou, Shuo; Shapiro, Michael A; Wansink, Brian

2017-01-01

Media's presentation of eating is an important source of influence on viewers' eating goals and behaviors. Drawing on recent research indicating that whether a story character continues to pursue a goal or completes a goal can unconsciously influence an audience member's goals, a scene from a popular movie comedy was manipulated to end with a character continuing to eat (goal ongoing) or completed eating (goal completed). Participants (N = 147) were randomly assigned to a goal status condition. As a reward, after viewing the movie clip viewers were offered two types of snacks: ChexMix and M&M's, in various size portions. Viewers ate more food after watching the characters continue to eat compared to watching the characters complete eating, but only among those manipulated to identify with a character. Viewers were more likely to choose savory food after viewing the ongoing eating scenes, but sweet dessert-like food after viewing the completed eating scenes. The results extend the notion of media influence on unconscious goal contagion and satiation to movie eating, and raise the possibility that completing a goal can activate a logically subsequent goal. Implications for understanding media influence on eating and other health behaviors are discussed. Copyright © 2016 Elsevier Ltd. All rights reserved.

NASA's Microgravity Science Research Program

NASA Technical Reports Server (NTRS)

1996-01-01

The ongoing challenge faced by NASA's Microgravity Science Research Program is to work with the scientific and engineering communities to secure the maximum return from our Nation's investments by: assuring that the best possible science emerges from the science community for microgravity investigations; ensuring the maximum scientific return from each investigation in the most timely and cost-effective manner; and enhancing the distribution of data and applications of results acquired through completed investigations to maximize their benefits.

Invasive Species Science Update (No. 8)

Treesearch

Dean Pearson; Yvette Ortega; Jack Butler

2015-01-01

Invasive Species Science Updates are designed to keep managers and other users up-to-date with recently completed and ongoing research by RMRS scientists, as well as highlight breaking news related to invasive species issues. The newsletter is produced by the RMRS Invasive Species Working Group (ISWG), which is a core group of scientists who volunteer to coordinate...

Embracing the Ambiguity: Twelve Considerations for Holistic Time Management

ERIC Educational Resources Information Center

Bresciani, Marilee J.; Duncan, Allison J.; Cao, Liu Hui

2010-01-01

Many people feel overwhelmed by the seemingly never-ending demands of their professional and personal lives. Thinking of one's life as an ongoing journey promotes flexibility and allows one to focus on a current task, while knowing there will be time in the future to complete other tasks or meet other goals later. Research has also shown that…

Invasive Species Science Update (No. 7)

Treesearch

Dean Pearson; Yvette Ortega; Jack Butler

2014-01-01

Invasive Species Science Updates are designed to keep managers and other users up-to-date with recently completed and ongoing research by RMRS scientists, as well as highlight breaking news related to invasive species issues. The newsletter is produced by the RMRS Invasive Species Working Group (ISWG), which is a core group of scientists who volunteer to coordinate...

Examining the Factors, Which Compel Online Graduate Students to Seek Academic Assistance

ERIC Educational Resources Information Center

Daines, Ramon

2017-01-01

The number of graduate level students who do not complete their degree has been an ongoing issue in higher education and has increased with the growth of online education. Research demonstrates that online learners who have already achieved their degree could manage their learning experience, understood the importance of seeking help when…

The Effects of Social Promotion and High-Stakes Tests on High School Completion

ERIC Educational Resources Information Center

Rader, Laura Pope

2016-01-01

Social promotion is an ongoing issue in education and is frequently seen as a dichotomy with retention. While retention is a commonly researched topic, the information regarding the academic and behavioral outcomes of socially promoted students is much sparser. The problem is that many students who are socially promoted into high school after…

Invasive Species Science Update (No. 9)

Treesearch

Justin Runyon

2017-01-01

This newsletter is designed to keep managers and other users up-to-date with recently completed and ongoing research by RMRS scientists, as well as to highlight breaking news related to invasive species issues. The newsletter is produced by the RMRS Invasive Species Working Group (ISWG), a core group of scientists who volunteer to disseminate RMRS invasive species...

Examination of an Administrator-Read Vocabulary-Matching Measure as an Indicator of Science Achievement

ERIC Educational Resources Information Center

Borsuk, Ellen R.

2010-01-01

Research and development of measures to document ongoing learning within the content areas are in the beginning stages. As such, the current study adds to efforts in the development of the vocabulary-matching measure. Using a modified format of the previously studied vocabulary-matching measure, 63 middle school students completed alternate forms…

Final Report for Research Conducted at The Scripps Institution of Oceanography, University of California San Diego from 2/2002 to 8/2003 for ''Aerosol and Cloud-Field Radiative Effects in the Tropical Western Pacific: Analyses and General Circulation Model Parameterizations''

DOE Office of Scientific and Technical Information (OSTI.GOV)

Vogelmann, A. M.

OAK-B135 Final report from the University of California San Diego for an ongoing research project that was moved to Brookhaven National Laboratory where proposed work will be completed. The research uses measurements made by the Atmospheric Radiation Measurement (ARM) Program to quantify the effects of aerosols and clouds on the Earth's energy balance in the climatically important Tropical Western Pacific.

Malaria vaccine clinical trials: what’s on the horizon

PubMed Central

Moreno, Alberto; Joyner, Chester

2015-01-01

Significant progress towards a malaria vaccine, specifically for Plasmodium falciparum, has been made in the past few years with the completion of numerous clinical trials. Each trial has utilized a unique combination of antigens, delivery platforms, and adjuvants, and the data that has been obtained provides critical information that has poises the research community for the development of next generation malaria vaccines. Despite the progress towards a P. falciparum vaccine, P. vivax vaccine research requires more momentum and additional investigations to identify novel vaccine candidates. In this review, recently completed and ongoing malaria vaccine clinical trials as well as vaccine candidates that are in the development pipeline are reviewed. Perspectives for future research using post-genomic mining, nonhuman primate models, and systems biology are also discussed. PMID:26172291

Exploring Contemporary Legal Issues in Schools from a Social Justice Frame: The Need for Ongoing Professional Development and Training for Practicing Educational Leaders

ERIC Educational Resources Information Center

Brackett, David A.; Perreault, George; Sparkman, William; Thornton, Billy W.; Barclay, Nicholas

2014-01-01

Most educational leadership preparation programs include classes designed to provide a broad survey of legal issues in the profession. Soon after these future leaders complete course requirements, their knowledge base can be outdated. We discuss, through relevant research along with theoretical and actual case studies, contemporary legal issues…

Mathematical Preparedness for Tertiary Mathematics--A Need for Focused Intervention in the First Year?

ERIC Educational Resources Information Center

Du Preez, Jeanetta; Steyn, Tobia; Owen, Rina

2008-01-01

Ongoing action research at the University of Pretoria investigates first-year students' preparedness for a study in calculus. In 2005 first-year engineering students completed a mathematics diagnostic survey at the beginning and end of the year. In this article the results of the 2005 survey are compared with the students' final school marks in…

International Space Station Science Research Accomplishments During the Assembly Years: An Analysis of Results from 2000-2008

NASA Technical Reports Server (NTRS)

Evans, Cynthia A.; Robinson, Julie A.; Tate-Brown, Judy; Thumm, Tracy; Crespo-Richey, Jessica; Baumann, David; Rhatigan, Jennifer

2009-01-01

This report summarizes research accomplishments on the International Space Station (ISS) through the first 15 Expeditions. When research programs for early Expeditions were established, five administrative organizations were executing research on ISS: bioastronautics research, fundamental space biology, physical science, space product development, and space flight. The Vision for Space Exploration led to changes in NASA's administrative structures, so we have grouped experiments topically by scientific themes human research for exploration, physical and biological sciences, technology development, observing the Earth, and educating and inspiring the next generation even when these do not correspond to the administrative structure at the time at which they were completed. The research organizations at the time at which the experiments flew are preserved in the appendix of this document. These investigations on the ISS have laid the groundwork for research planning for Expeditions to come. Humans performing scientific investigations on ISS serve as a model for the goals of future Exploration missions. The success of a wide variety of investigations is an important hallmark of early research on ISS. Of the investigations summarized here, some are completed with results released, some are completed with preliminary results, and some remain ongoing.

International Utilization at the Threshold of "Assembly Complete"- Science Returns from the International Space Station

NASA Technical Reports Server (NTRS)

Robinson, Julie A.

2009-01-01

The European Columbus and Japanese Kibo laboratories are now fully operational on the International Space Station (ISS), bringing decades of international planning to fruition. NASA is now completing launch and activation of major research facilities that will be housed in the Destiny U.S. Laboratory, Columbus, and Kibo. These facilities include major physical sciences capabilities for combustion, fluid physics, and materials science, as well as additional multipurpose and supporting infrastructure. Expansion of the laboratory space and expansion to a 6-person crew (planned for May 2009), is already leading to significant increases in research throughput even before assembly is completed. International research on the ISS includes exchanges of results, sharing of facilities, collaboration on experiments, and joint publication and communication of accomplishments. Significant and ongoing increases in research activity on ISS have occurred over the past year. Although research results lag behind on-orbit operations by 2-5 years, the surge of early research activities following Space Shuttle return to flight in 2005 is now producing an accompanying surge in scientific publications. Evidence of scientific productivity from early utilization opportunities combined with the current pace of research activity in orbit are both important parts of the evidence base for evaluating the potential future achievements of a complete and active ISS.

The hydrogen technology assessment, phase 1

NASA Technical Reports Server (NTRS)

Bain, Addison

1991-01-01

The purpose of this phase 1 report is to begin to form the information base of the economics and energy uses of hydrogen-related technologies on which the members of the National Hydrogen Association (NHA) can build a hydrogen vision of the future. The secondary goal of this report is the development of NHA positions on national research, development, and demonstration opportunities. The third goal, with the aid of the established hydrogen vision and NHA positions, is to evaluate ongoing federal research goals and activities. The evaluations will be performed in a manner that compares the costs associated with using systems that achieve those goals against the cost of performing those tasks today with fossil fuels. From this ongoing activity should emerge an NHA information base, one or more hydrogen visions of the future, and cost and performance targets for hydrogen applications to complete in the market place.

Bibliotherapy and information prescriptions: a summary of the published evidence-base and recommendations from past and ongoing Books on Prescription projects.

PubMed

Chamberlain, D; Heaps, D; Robert, I

2008-01-01

This paper summarizes the published evidence and reports from ongoing and completed projects that used Bibliotherapy and Information Prescription to deliver patient care. A literature search was conducted and relevant papers were summarized into: type of study, type of Bibliotherapy, client group and recommendations. In total, 65 papers were considered with 57 reviewed. A survey was also sent to Library Authorities subscribing to national survey standards asking for details about delivery of Information Prescription projects. There were 21 returned surveys. The experiences and recommendations were then summarized. The aim of the paper is to collate the evidence-base of written research and the experience and recommendations of projects into an easy format so that practitioners interested in using Bibliotherapy/Information Prescription/Books on Prescription have an understanding what they are, the extent of the evidence-base to inform practice, and highlight gaps in the research.

Clean Cities Technical Assistance Project (Tiger Teams)

DOE Office of Scientific and Technical Information (OSTI.GOV)

This two-page fact sheet describes Clean Cities' technical assistance (Tiger Teams) capabilities and projects, both completed and ongoing. Tiger Teams are a critical element of the Clean Cities program, providing on-the-ground consultation to help inform program strategies. The knowledge Tiger Team experts gain from these experiences often helps inform other alternative fuels activities, such as needed research, codes and standards revisions, and new training resources.

Evaluation of an ongoing psychoeducational inflammatory bowel disease support group in an adult outpatient setting.

PubMed

McMaster, Kristin; Aguinaldo, Laika; Parekh, Nimisha K

2012-01-01

Previous studies assessing efficacy of support groups for patients with inflammatory bowel disease showed mixed results in terms of attendance and overall effectiveness. In this study, researchers evaluated the use of an ongoing open psychoeducational support group for adult patients with inflammatory bowel disease in an outpatient tertiary setting. The sample consisted of 18 adults who have attended more than 2 meetings of the support group. Topics addressed in the support group include complementary medicine, diet and nutrition, the psychological impact of inflammatory bowel disease, medication and side effects, and insurance/disability. Participants were asked to complete the Client Satisfaction Questionnaire, Multidimensional Support Scale, 11 general demographic questions, and a brief open-ended qualitative questionnaire developed by the researchers. Results demonstrated that participants reported very high satisfaction with the support group and rated the adequacy of peer support from others with inflammatory bowel disease higher than support from family/friends and professionals. A majority of group members reported joining the group for mutual support and education; this expectation was met through the psychoeducational structure of the group. This study demonstrates the potential for success of an ongoing psychoeducational inflammatory bowel disease support group for adult patients and their caregivers.

Reasons for Non-Completion and Dissatisfaction among Apprentices and Trainees: A Regional Case Study

ERIC Educational Resources Information Center

Hart, Alison; Snell, Darryn

2008-01-01

Skills shortages have reinvigorated ongoing debate and concern about high attrition rates among Australian apprentices and trainees. Low apprentice and trainee wages have often been cited to explain this ongoing problem. This paper discusses the factors contributing to non-completion among apprentices and trainees in regional Victoria, and how the…

Validation of Biomarkers for Prostate Cancer Prognosis

DTIC Science & Technology

2014-12-01

and Muc1. We have also completed a project in image analysis of H & E slides with Gustavo Ayala at University of Texas. Finally, we have completed...Groups using the resource include Dr. Jeremy Squire, Dr. Gustavo Ayala, Tamara Lotan and Dr. Lidong Liu. • Porting final clinical data that will be...with a manuscript near completion. • Ongoing analysis of AZGP1 with a manuscript expected soon. • Ongoing analysis of image analysis with Gustavo Ayala

The Marine Fire Support Team as a Model for Distributed Operations Analysis: Review of Prior Analyses, Summary of Ongoing Research, and Recommendations for Future Work

DTIC Science & Technology

2008-07-17

without excessive procrastination ; to work independently and accomplish tasks without constant supervision; to take personal responsibility for completing...difficult tasks without excessive procrastination ; to work independently and accomplish tasks without constant supervision; to take personal...tasks without excessive procrastination ; to work independently and accomplish tasks without constant supervision; to take personal responsibility for

Applied statistical training to strengthen analysis and health research capacity in Rwanda.

PubMed

Thomson, Dana R; Semakula, Muhammed; Hirschhorn, Lisa R; Murray, Megan; Ndahindwa, Vedaste; Manzi, Anatole; Mukabutera, Assumpta; Karema, Corine; Condo, Jeanine; Hedt-Gauthier, Bethany

2016-09-29

To guide efficient investment of limited health resources in sub-Saharan Africa, local researchers need to be involved in, and guide, health system and policy research. While extensive survey and census data are available to health researchers and program officers in resource-limited countries, local involvement and leadership in research is limited due to inadequate experience, lack of dedicated research time and weak interagency connections, among other challenges. Many research-strengthening initiatives host prolonged fellowships out-of-country, yet their approaches have not been evaluated for effectiveness in involvement and development of local leadership in research. We developed, implemented and evaluated a multi-month, deliverable-driven, survey analysis training based in Rwanda to strengthen skills of five local research leaders, 15 statisticians, and a PhD candidate. Research leaders applied with a specific research question relevant to country challenges and committed to leading an analysis to publication. Statisticians with prerequisite statistical training and experience with a statistical software applied to participate in class-based trainings and complete an assigned analysis. Both statisticians and research leaders were provided ongoing in-country mentoring for analysis and manuscript writing. Participants reported a high level of skill, knowledge and collaborator development from class-based trainings and out-of-class mentorship that were sustained 1 year later. Five of six manuscripts were authored by multi-institution teams and submitted to international peer-reviewed scientific journals, and three-quarters of the participants mentored others in survey data analysis or conducted an additional survey analysis in the year following the training. Our model was effective in utilizing existing survey data and strengthening skills among full-time working professionals without disrupting ongoing work commitments and using few resources. Critical to our success were a transparent, robust application process and time limited training supplemented by ongoing, in-country mentoring toward manuscript deliverables that were led by Rwanda's health research leaders.

Vibro-Acoustics Modal Testing at NASA Langley Research Center

NASA Technical Reports Server (NTRS)

Pappa, Richard S.; Pritchard, Jocelyn I.; Buehrle, Ralph D.

1999-01-01

This paper summarizes on-going modal testing activities at the NASA Langley Research Center for two aircraft fuselage structures: a generic "aluminum testbed cylinder" (ATC) and a Beechcraft Starship fuselage (BSF). Subsequent acoustic tests will measure the interior noise field created by exterior mechanical and acoustic sources. These test results will provide validation databases for interior noise prediction codes on realistic aircraft fuselage structures. The ATC is a 12-ft-long, all-aluminum, scale model assembly. The BSF is a 40-ft-long, all-composite, complete aircraft fuselage. To date, two of seven test configurations of the ATC and all three test configurations of the BSF have been completed. The paper briefly describes the various test configurations, testing procedure, and typical results for frequencies up to 250 Hz.

Advanced light source: Compendium of user abstracts and technical reports,1993-1996

DOE Office of Scientific and Technical Information (OSTI.GOV)

None, None

1997-04-01

This compendium contains abstracts written by users summarizing research completed or in progress from 1993-1996, ALS technical reports describing ongoing efforts related to improvement in machine operations and research and development projects, and information on ALS beamlines planned through 1998. Two tables of contents organize the user abstracts by beamline and by area of research, and an author index makes abstracts accessible by author and by principal investigator. Technical details for each beamline including whom to contact for additional information can be found in the beamline information section. Separate abstracts have been indexed into the database for contributions to thismore » compendium.« less

Biology and therapy of fibromyalgia. Evidence-based biomarkers for fibromyalgia syndrome

PubMed Central

Dadabhoy, Dina; Crofford, Leslie J; Spaeth, Michael; Russell, I Jon; Clauw, Daniel J

2008-01-01

Researchers studying fibromyalgia strive to identify objective, measurable biomarkers that may identify susceptible individuals, may facilitate diagnosis, or that parallel activity of the disease. Candidate objective measures range from sophisticated functional neuroimaging to office-ready measures of the pressure pain threshold. A systematic literature review was completed to assess highly investigated, objective measures used in fibromyalgia studies. To date, only experimental pain testing has been shown to coincide with improvements in clinical status in a longitudinal study. Concerted efforts to systematically evaluate additional objective measures in research trials will be vital for ongoing progress in outcome research and translation into clinical practice. PMID:18768089

A retrospective review of clopidogrel as primary therapy for migraineurs with right to left shunt lesions.

PubMed

Spencer, Barbara T; Qureshi, Yasir; Sommer, Robert J

2014-10-01

The association of patient foramen ovale (PFO) and migraine headache (migraine) with aura (MA) is well established. Current research suggests a mechanistic link between platelet activation, paradoxical embolization and migraine in some patients. Clopidogrel, a platelet inhibitor, was added to existing migraine therapy, as a 4-week open-label trial in 15 women, aged 16-56 years, with severe migraine and documented right to left shunt (RLS). 13/15 had > 50% reduction or complete elimination of migraine symptoms. After completing the trial period, five responders remain on clopidogrel with ongoing benefit at 11.9 ± 4.5 months (6.5-20), one stopped clopidogrel because of side effects. Nine other responders underwent PFO closure and clopidogrel discontinuation. Eight of nine have had ongoing benefit. Clopidogrel may have a primary prophylactic role in migraine/RLS patients, but may also help select candidates who would benefit from PFO closure. A randomized clinical trial is being established. © International Headache Society 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

Coding a Weather Model: DOE-FIU Science & Technology Workforce Development Program.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bradley, Jon David

DOE Fellow, Andres Cremisini, completed a 10-week internship with Sandia National Laboratories (SNL) in Albuquerque, New Mexico. Under the management of Kristopher Klingler and the mentorship of Jon Bradley, he was tasked with conceiving and coding a realistic weather model for use in physical security applications. The objective was to make a weather model that could use real data to accurately predict wind and precipitation conditions at any location of interest on the globe at any user-determined time. The intern received guidance on software design, the C++ programming language and clear communication of project goals and ongoing progress. In addition,more » Mr. Cremisini was given license to structure the program however he best saw fit, an experience that will benefit ongoing research endeavors.« less

Harvard Aging Brain Study: Dataset and accessibility.

PubMed

Dagley, Alexander; LaPoint, Molly; Huijbers, Willem; Hedden, Trey; McLaren, Donald G; Chatwal, Jasmeer P; Papp, Kathryn V; Amariglio, Rebecca E; Blacker, Deborah; Rentz, Dorene M; Johnson, Keith A; Sperling, Reisa A; Schultz, Aaron P

2017-01-01

The Harvard Aging Brain Study is sharing its data with the global research community. The longitudinal dataset consists of a 284-subject cohort with the following modalities acquired: demographics, clinical assessment, comprehensive neuropsychological testing, clinical biomarkers, and neuroimaging. To promote more extensive analyses, imaging data was designed to be compatible with other publicly available datasets. A cloud-based system enables access to interested researchers with blinded data available contingent upon completion of a data usage agreement and administrative approval. Data collection is ongoing and currently in its fifth year. Copyright © 2015 Elsevier Inc. All rights reserved.

Physical Studies of Brown Dwarfs and Extrasolar Planets

NASA Technical Reports Server (NTRS)

Noll, Keith

2004-01-01

The main purpose of this grant proposal was to fund the ongoing work on brown dwarfs by Denise Stephens during her tenure at STScI as a postdoctoral researcher. We have completed approximately half of the three-year grant period. Dr. Stephens has now assumed to role of senior research associate at Johns Hopkins University and in this position is eligible to be PI of grants. Because the bulk of the work and funds under this grant have been and will continue to be for the purposes of supporting Dr. Stephens, we are transferring control of the grant to her at JHU. This closeout is a formality to allow that transfer. The largest project was the completion of a major work on the infrared photometry of L and T dwarfs. The paper was published in January 2004.

Telepresence system development for application to the control of remote robotic systems

NASA Technical Reports Server (NTRS)

Crane, Carl D., III; Duffy, Joseph; Vora, Rajul; Chiang, Shih-Chien

1989-01-01

The recent developments of techniques which assist an operator in the control of remote robotic systems are described. In particular, applications are aimed at two specific scenarios: The control of remote robot manipulators; and motion planning for remote transporter vehicles. Common to both applications is the use of realistic computer graphics images which provide the operator with pertinent information. The specific system developments for several recently completed and ongoing telepresence research projects are described.

Prediction of Acute Mountain Sickness Using a Blood Based Test

DTIC Science & Technology

2017-01-01

reporting burden for this collection of information is estimated to average 1 hour per response, including the time for reviewing instructions, searching...develop acute mountain sickness (AMS) when they travel to high altitudes. OVERALL PROJECT SUMMARY: Following program reviews over the last 24 months we...research. That work is ongoing and will continue for remainder of the time we work on this grant. We completed the request for a no cost extension. And we

Coverage Metrics for Model Checking

NASA Technical Reports Server (NTRS)

Penix, John; Visser, Willem; Norvig, Peter (Technical Monitor)

2001-01-01

When using model checking to verify programs in practice, it is not usually possible to achieve complete coverage of the system. In this position paper we describe ongoing research within the Automated Software Engineering group at NASA Ames on the use of test coverage metrics to measure partial coverage and provide heuristic guidance for program model checking. We are specifically interested in applying and developing coverage metrics for concurrent programs that might be used to support certification of next generation avionics software.

Comprehensive Evaluation of Altered Systemic Metabolism and Pancreatic Cancer Risk

DTIC Science & Technology

2015-10-01

aspirin and β-carotene among 22 071 male physicians, age 40 to 84 years. After trial completion in 1995, participants were followed as an observational...report on the aspirin component of the ongoing Physicians’ Health Study. Steering Committee of the Physicians’ Health Study Research Group. N Engl...Study I (PHS I) is a randomized clinical trial of aspirin and β-carotene that enrolled 22,071 male physicians aged 40 to 84 years in 1982. After

Strategies to successfully recruit and engage clinical nurses as participants in qualitative clinical research.

PubMed

Coyne, Elisabeth; Grafton, Eileen; Reid, Alayne

2016-12-01

Research conducted in the clinical area promotes the delivery of evidence-based patient care. Involving nurses as participants in research is considered essential to link patient care with evidence-based interventions. However recruitment is influenced by nurses' competing demands and understanding engagement strategies may assist future research. This reflective analysis aimed to understand influencing factors and strategies that support successful recruitment nurses in clinical research. A reflective analysis of research notes and focus group data from research with oncology nurses was completed. This research identified that gaining support from key staff, understanding work constraints and developing a rapport with nurses is important. Establishing clear relevance and benefits of the research and being flexible with research requirements enabled nurses to participate in the research. Clear information and a willingness to accommodate the demands and dynamic nature of the environment, ensures ongoing support and engagement of nurses in the clinical setting as participants in research.

Perspectives of HER2-targeting in gastric and esophageal cancer.

PubMed

Gerson, James N; Skariah, Sam; Denlinger, Crystal S; Astsaturov, Igor

2017-05-01

The blockade of HER2 signaling has significantly improved the outlook for esophagogastric cancer patients. However, targeting HER2 still remains challenging due to complex biology of this receptor in gastric and esophageal cancers. Areas covered: Here, we review complex HER2 biology, current methods of HER2 testing and tumor heterogeneity of gastroesophageal cancer. Ongoing and completed clinical research data are discussed. Expert opinion: HER2 overexpression is a validated target in gastroesophageal cancer, with therapeutic implications resulting in prolonged survival when inhibited in the front-line setting. With standardized HER2 testing in gastro-esophageal cancer, the ongoing trials are testing newer agents and combinations including combination of anti-HER2 antibodies with immunotherapy. Clonal heterogeneity and emergence of resistance will challenge our approach to treating these patients beyond the frontline settings.

Toward genome-enabled mycology.

PubMed

Hibbett, David S; Stajich, Jason E; Spatafora, Joseph W

2013-01-01

Genome-enabled mycology is a rapidly expanding field that is characterized by the pervasive use of genome-scale data and associated computational tools in all aspects of fungal biology. Genome-enabled mycology is integrative and often requires teams of researchers with diverse skills in organismal mycology, bioinformatics and molecular biology. This issue of Mycologia presents the first complete fungal genomes in the history of the journal, reflecting the ongoing transformation of mycology into a genome-enabled science. Here, we consider the prospects for genome-enabled mycology and the technical and social challenges that will need to be overcome to grow the database of complete fungal genomes and enable all fungal biologists to make use of the new data.

Supplement Analysis for Yakima/Klickitat Fisheries Project, (DOE/EIS-0169-SA-05)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Smith, Patricia R.

2002-09-20

Yakima/Klickitat Fisheries Project – Under the Monitoring and Evaluation Program (M&E), the domestication selection research task would be modified to include a hatchery control line, maintained entirely by spawning hatchery-origin fish. The Bonneville Power Administration is funding ongoing studies, research, and artificial production of several salmonid species in the Yakima and Klickitat river basins. BPA analyzed environmental impacts of research and supplementation projects in the Yakima basin in an Environmental Impact Statement (EIS) completed in 1996 (USDOE/BPA 1996), and in the following Supplement Analyses: DOE/EIS-0169-SA-01, completed in May 1999; DOE/EIS-0169-SA-02, completed in August 1999; DOE/EIS-0169-SA-03, completed in 2000; DOE/EIS-0169-SA-04, completedmore » in November 2000. The purpose of this Supplement Analysis is to determine if a Supplemental EIS is needed to analyze the changes proposed in the Monitoring and Evaluation program (#199506325) of the Yakima Klickitat Fisheries Project (YKFP) as reviewed in the FY 2001 Project Proposals for the Columbia River Gorge and Inter-Mountain Provinces, ISRP 2000-9 (December 1, 2000). Modifications to the M&E program are in support of the experimental acclimation, rearing and incubating activities for spring chinook.« less

Applying Dust-on-Snow Research to Colorado Water Management

NASA Astrophysics Data System (ADS)

Landry, C. C.; Painter, T. H.; Barrett, A. P.

2008-12-01

Snowmelt runoff from seasonal snowpacks in Western mountains provides a high proportion of regional water supplies and represents a critical resource subject to complex management imperatives at all levels of local, state, and federal government. Recent research performed in the San Juan Mountains of Southwest Colorado has revealed that deposition of desert dust from the Colorado Plateau onto Colorado mountain snowpacks is playing a hitherto underestimated forcing role in snowmelt timing and intensity. In spring 2006, embedded dust layers forced a 4-5 week advance in complete snowpack ablation at the Senator Beck Basin Study Area, near Red Mountain Pass, and professional water managers throughout Colorado were surprised by an early and compressed snowmelt runoff. Presentations of our preliminary findings during the summer of 2006 at local water district meetings and at a statewide forum resonated with Colorado water managers and resulted in direct stakeholder engagement in the ongoing research program during the subsequent winter. In spring 2007 the research team issued periodic Dust Alerts describing dust-on-snow conditions extant within the study area, as well as anecdotal reports of conditions elsewhere in the state, and discussed the snowmelt ramifications of those dust conditions in the coming 7-15 days, given mid-range NWS weather forecasts. Another round of presentations at district and state-wide stakeholder meetings in summer 2007 resulted in additional districts and agencies engaging in the program and expanding the dust-on-snow monitoring and Dust Alert analysis efforts in spring 2008 to additional sites distributed throughout the state. The original research project is ongoing and the team is now developing a Colorado Dust-on-Snow Program, CODOS, designed to serve all stakeholders in Colorado snowmelt with increasingly intensive monitoring and analysis of snowmelt forcing by dust, and with ongoing research regarding dust-driven mountain snowmelt processes. In this instance, basic science preceded stakeholder engagement and, through active outreach, a consequential, stakeholder-supported program implementing operational application of the research is emerging.

Identifying Androgen Receptor-Independent Mechanisms of Prostate Cancer Resistance to Second-Generation Antiandrogen Therapy

DTIC Science & Technology

2016-08-01

expanded upon the relationship between GR and SGK1 in the context of enzalutamide-driven prostate cancer. We have generated CRISPR /Cas9 cell lines...Complete Generate SGK1 overexpressing cell models 50% Ongoing Clone SGK1 CRISPR 100% Complete Generate SGK1-deficient cell models 75% Ongoing Test...driven enzalutamide resistance, GR-expressing enzalutamide-resistant prostate cancer cells expressing CRISPR /Cas9 and a guide targeting SGK1 (sgSGK1

Historical perspectives and future directions in the surgical management of retroperitoneal sarcoma.

PubMed

Tseng, William W; Seo, Hyun Jae; Pollock, Raphael E; Gronchi, Alessandro

2018-01-01

Retroperitoneal sarcomas (RPS) have fascinated and intrigued physicians both past and present. Operative mortality rates were historically very high and complete resection was not possible for the majority of patients until only the last 2 decades. More recently, changes to the surgical approach and clinical decision-making in RPS have improved patient outcomes. With select integration of nonsurgical therapies, continued RPS-specific research, and ongoing collaborative efforts among major referral centers, the future appears promising. © 2017 Wiley Periodicals, Inc.

Early Intervention to Reduce Alcohol Misuse and Abuse in the Ohio Army National Guard

DTIC Science & Technology

2017-09-01

reports on app data once the study starts • CHCR continued to make adjustments and updates to the app as needed when issues have been noted by...Toledo hired their research coordinator for the project in October 2016. Since then the study team worked to complete training on all assessments and...the data coordinator trained study coordinators on how to use REDCap and has provided ongoing assistance as needed. The study was approved by

A physical activity program to mobilize older people: a practical and sustainable approach.

PubMed

Jancey, Jonine M; Clarke, Ann; Howat, Peter A; Lee, Andy H; Shilton, Trevor; Fisher, John

2008-04-01

Despite the documented benefits of physical activity, it remains difficult to motivate older adults to start and maintain regular physical activity. This study tested an innovative intervention for mobilizing older adults into a neighborhood-based walking program. Researchers recruited a total of 260 healthy but insufficiently active adults aged 65 to 74 years and randomly selected from the Australian electoral roll from 30 Perth metropolitan neighborhoods. Social cognitive theory guided the design of the program. Researchers collected both qualitative and quantitative data to inform the development, together with ongoing process evaluation. A total of 65% of participants completed the program. Their mean weekly walking time for recreation increased by about 100 min, and 80% of participants reported that they would continue to walk twice per week upon program completion. This practical program is potentially effective and sustainable with respect to mobilizing physically inactive older people.

Acquisition of Cleanroom Research Equipment to Support Ongoing DoD Programs at ASU

DTIC Science & Technology

2017-12-12

Report: Acquisition of cleanroom research equipment to support ongoing DoD programs at ASU The views, opinions and/or findings contained in this report...documentation. 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS (ES) U.S. Army Research Office P.O. Box 12211 Research Triangle Park, NC 27709...Agreement Number: W911NF-16-1-0354 Organization: Arizona State University Title: Acquisition of cleanroom research equipment to support ongoing DoD

Satellite Delivery of Aviation Weather Data

NASA Technical Reports Server (NTRS)

Kerczewski, Robert J.; Haendel, Richard

2001-01-01

With aviation traffic continuing to increase worldwide, reducing the aviation accident rate and aviation schedule delays is of critical importance. In the United States, the National Aeronautics and Space Administration (NASA) has established the Aviation Safety Program and the Aviation System Capacity Program to develop and test new technologies to increase aviation safety and system capacity. Weather is a significant contributor to aviation accidents and schedule delays. The timely dissemination of weather information to decision makers in the aviation system, particularly to pilots, is essential in reducing system delays and weather related aviation accidents. The NASA Glenn Research Center is investigating improved methods of weather information dissemination through satellite broadcasting directly to aircraft. This paper describes an on-going cooperative research program with NASA, Rockwell Collins, WorldSpace, Jeppesen and American Airlines to evaluate the use of satellite digital audio radio service (SDARS) for low cost broadcast of aviation weather information, called Satellite Weather Information Service (SWIS). The description and results of the completed SWIS Phase 1 are presented, and the description of the on-going SWIS Phase 2 is given.

The Role of Integrated Knowledge Translation in Intervention Research.

PubMed

Wathen, C Nadine; MacMillan, Harriet L

2018-04-01

There is widespread recognition across the full range of applied research disciplines, including health and social services, about the challenges of integrating scientifically derived research evidence into policy and/or practice decisions. These "disconnects" or "knowledge-practice gaps" between research production and use have spawned a new research field, most commonly known as either "implementation science" or "knowledge translation." The present paper will review key concepts in this area, with a particular focus on "integrated knowledge translation" (IKT)-which focuses on researcher-knowledge user partnership-in the area of mental health and prevention of violence against women and children using case examples from completed and ongoing work. A key distinction is made between the practice of KT (disseminating, communicating, etc.), and the science of KT, i.e., research regarding effective KT approaches. We conclude with a discussion of the relevance of IKT for mental health intervention research with children and adolescents.

Leveraging Social Networking Sites for an Autoimmune Hepatitis Genetic Repository: Pilot Study to Evaluate Feasibility.

PubMed

Comerford, Megan; Fogel, Rachel; Bailey, James Robert; Chilukuri, Prianka; Chalasani, Naga; Lammert, Craig Steven

2018-01-18

Conventional approaches to participant recruitment are often inadequate in rare disease investigation. Social networking sites such as Facebook may provide a vehicle to circumvent common research limitations and pitfalls. We report our preliminary experience with Facebook-based methodology for participant recruitment and participation into an ongoing study of autoimmune hepatitis (AIH). The goal of our research was to conduct a pilot study to assess whether a Facebook-based methodology is capable of recruiting geographically widespread participants into AIH patient-oriented research and obtaining quality phenotypic data. We established a Facebook community, the Autoimmune Hepatitis Research Network (AHRN), in 2014 to provide a secure and reputable distillation of current literature and AIH research opportunities. Quarterly advertisements for our ongoing observational AIH study were posted on the AHRN over 2 years. Interested and self-reported AIH participants were subsequently enrolled after review of study materials and completion of an informed consent by our study coordinator. Participants returned completed study materials, including epidemiologic questionnaires and genetic material, to our facility via mail. Outside medical records were obtained and reviewed by a study physician. We successfully obtained all study materials from 29 participants with self-reported AIH within 2 years from 20 different states. Liver biopsy results were available for 90% (26/29) of participants, of which 81% (21/29) had findings consistent with AIH, 15% (4/29) were suggestive of AIH with features of primary biliary cholangitis (PBC), and 4% (1/29) had PBC alone. A total of 83% (24/29) had at least 2 of 3 proposed criteria: positive autoimmune markers, consistent histologic findings of AIH on liver biopsy, and reported treatment with immunosuppressant medications. Self-reported and physician records were discrepant for immunosuppressant medications or for AIH/PBC diagnoses in 4 patients. Facebook can be an effective ancillary tool for facilitating patient-oriented research in rare diseases. A social media-based approach transcends established limitations in rare disease research and can further develop research communities. ©Megan Comerford, Rachel Fogel, James Robert Bailey, Prianka Chilukuri, Naga Chalasani, Craig Steven Lammert. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 18.01.2018.

Leveraging Social Networking Sites for an Autoimmune Hepatitis Genetic Repository: Pilot Study to Evaluate Feasibility

PubMed Central

Bailey, James Robert; Chilukuri, Prianka; Chalasani, Naga

2018-01-01

Background Conventional approaches to participant recruitment are often inadequate in rare disease investigation. Social networking sites such as Facebook may provide a vehicle to circumvent common research limitations and pitfalls. We report our preliminary experience with Facebook-based methodology for participant recruitment and participation into an ongoing study of autoimmune hepatitis (AIH). Objective The goal of our research was to conduct a pilot study to assess whether a Facebook-based methodology is capable of recruiting geographically widespread participants into AIH patient-oriented research and obtaining quality phenotypic data. Methods We established a Facebook community, the Autoimmune Hepatitis Research Network (AHRN), in 2014 to provide a secure and reputable distillation of current literature and AIH research opportunities. Quarterly advertisements for our ongoing observational AIH study were posted on the AHRN over 2 years. Interested and self-reported AIH participants were subsequently enrolled after review of study materials and completion of an informed consent by our study coordinator. Participants returned completed study materials, including epidemiologic questionnaires and genetic material, to our facility via mail. Outside medical records were obtained and reviewed by a study physician. Results We successfully obtained all study materials from 29 participants with self-reported AIH within 2 years from 20 different states. Liver biopsy results were available for 90% (26/29) of participants, of which 81% (21/29) had findings consistent with AIH, 15% (4/29) were suggestive of AIH with features of primary biliary cholangitis (PBC), and 4% (1/29) had PBC alone. A total of 83% (24/29) had at least 2 of 3 proposed criteria: positive autoimmune markers, consistent histologic findings of AIH on liver biopsy, and reported treatment with immunosuppressant medications. Self-reported and physician records were discrepant for immunosuppressant medications or for AIH/PBC diagnoses in 4 patients. Conclusions Facebook can be an effective ancillary tool for facilitating patient-oriented research in rare diseases. A social media-based approach transcends established limitations in rare disease research and can further develop research communities. PMID:29348111

Sustaining health education research programs in Aboriginal communities.

PubMed

Wisener, Katherine; Shapka, Jennifer; Jarvis-Selinger, Sandra

2017-09-01

Despite evidence supporting the ongoing provision of health education interventions in First Nations communities, there is a paucity of research that specifically addresses how these programs should be designed to ensure sustainability and long-term effects. Using a Community-Based Research approach, a collective case study was completed with three Canadian First Nations communities to address the following research question: What factors are related to sustainable health education programs, and how do they contribute to and/or inhibit program success in an Aboriginal context? Semi-structured interviews and a sharing circle were completed with 19 participants, including members of community leadership, external partners, and program staff and users. Seven factors were identified to either promote or inhibit program sustainability, including: 1) community uptake; 2) environmental factors; 3) stakeholder awareness and support; 4) presence of a champion; 5) availability of funding; 6) fit and flexibility; and 7) capacity and capacity building. Each factor is provided with a working definition, influential moderators, and key evaluation questions. This study is grounded in, and builds on existing research, and can be used by First Nations communities and universities to support effective sustainability planning for community-based health education interventions.

Enhancing pediatric residents’ scholar role: the development of a Scholarly Activity Guidance and Evaluation program

PubMed Central

Pound, Catherine M.; Moreau, Katherine A.; Ward, Natalie; Eady, Kaylee; Writer, Hilary

2015-01-01

Background Research training is essential to the development of well-rounded physicians. Although many pediatric residency programs require residents to complete a research project, it is often challenging to integrate research training into educational programs. Objective We aimed to develop an innovative research program for pediatric residents, called the Scholarly Activity Guidance and Evaluation (SAGE) program. Methods We developed a competency-based program which establishes benchmarks for pediatric residents, while providing ongoing academic mentorship. Results Feedback from residents and their research supervisors about the SAGE program has been positive. Preliminary evaluation data have shown that all final-year residents have met or exceeded program expectations. Conclusions By providing residents with this supportive environment, we hope to influence their academic career paths, increase their research productivity, promote evidence-based practice, and ultimately, positively impact health outcomes. PMID:26059213

21 CFR 99.201 - Manufacturer's submission to the agency.

Code of Federal Regulations, 2011 CFR

2011-04-01

... dissemination, and unpublished manuscripts, abstracts, and data analyses from completed or ongoing..., completion of data collection, completion of data analysis, and submission of the supplemental application...., the databases or sources and criteria (i.e., subject headings/keywords) used to generate the...

Planetary Origin Evolution and Structure

NASA Technical Reports Server (NTRS)

Stevenson, David J.

2005-01-01

This wide-ranging grant supported theoretical modeling on many aspects of the formation, evolution and structure of planets and satellites. Many topics were studied during this grant period, including the evolution of icy bodies; the origin of magnetic fields in Ganymede; the thermal histories of terrestrial planets; the nature of flow inside giant planets (especially the coupling to the magnetic field) and the dynamics of silicate/iron mixing during giant impacts and terrestrial planet core formation. Many of these activities are ongoing and have not reached completion. This is the nature of this kind of research.

Open Rotor Test Status

NASA Technical Reports Server (NTRS)

VanZante, Dale E.

2010-01-01

Testing of low noise, counter-rotating open rotor propulsion concepts has been ongoing at Glenn Research Center in collaboration with General Electric Company. The presentation is an overview of the testing that has been completed to date and previews the upcoming test entries. The NASA Environmentally Responsible Aviation Project Diagnostics entry is the most recent to finish. That test entry included acoustic phased array, pressure sensitive paint, particle image velocimetry, pylon installed measurements and acoustic shielding measurements. A preview of the data to be acquired in the 8x6 high-speed wind tunnel is also included.

PCB-Caulk Replacement Project Johnson Space Center Houston, TX

NASA Technical Reports Server (NTRS)

Young, William M.; Stanch, Penney M.; Molenda, William

2011-01-01

Wet method reduced exposure by minimizing overall respirable particulate release. Dry method didn't introduce delays for primer/caulk application. Removed caulks came in many forms, from dry powdery to tarry sticky. Varying textures were not sampled or packaged differently. During the course of the project, EPA modified recommended practices to include full containment for exterior caulk removal. Changes are ongoing. Initial recommendations were directed to school buildings. EPA is researching risks due to caulk. Exposure guidance lacking except for 2 of 209 PCB congeners. Work was safely completed on schedule and under budget.

The use of reflective diaries in end of life training programmes: a study exploring the impact of self-reflection on the participants in a volunteer training programme.

PubMed

Germain, Alison; Nolan, Kate; Doyle, Rita; Mason, Stephen; Gambles, Maureen; Chen, Hong; Smeding, Ruthmarijke; Ellershaw, John

2016-03-05

A training programme was developed and delivered to a cohort of volunteers who were preparing for a unique role to provide companionship to dying patients in the acute hospital setting. This comprehensive programme aimed to provide an opportunity for participants to fully understand the nature and responsibilities of the role, whilst also allowing sufficient time to assess the qualities and competencies of participants for their ongoing volunteering role. Participants completed reflective diaries throughout the training course to record their ongoing thoughts and feelings. The purpose of this paper is to present a phenomenological analysis of these entries to understand participants' experiences, perceptions and motivations. The wider study was structured into three phases. Phase 1 was the delivery of a 12 week, bespoke training programme; Phase 2 involved a 26 week pilot implementation of the Care of the Dying Volunteer Service and Phase 3 was the research evaluation of the training and implementation which would inform the further development of the training programme. Self-reflection is a common component of End of Life training programmes and volunteers in this study completed a reflective diary after participation in each of the training sessions. A thematic analysis was undertaken to explore and understand the participants' experience, perceptions and motivations in relation to their participation in the training. All 19 volunteers completed the reflective diaries. From a potential 228 diary entries over the 12 week training programme, 178 diary entries were submitted (78 %). The following key themes were identified: Dying Alone and the importance of being present, Personal loss and the reconstruction of meaning, Self-Awareness and Personal growth, Self-preservation and Coping strategies and group unity/cohesion. The participants in this study demonstrated that they were able to use the diaries as an appropriate medium for reflection. Their reflections were also instrumental in the ongoing revision and development of the training programme. Analysis of their entries illustrated that the diaries could provide the opportunity for a reappraisal of their world view and personal philosophy around death and dying. Further research is undoubtedly required, however this paper suggests that self-reflection in this way, supports preparation in honing the appropriate attitudes and qualities required to work in this role.

Towards improving the ethics of ecological research.

PubMed

Crozier, G K D; Schulte-Hostedde, Albrecht I

2015-06-01

We argue that the ecological research community should develop a plan for improving the ethical consistency and moral robustness of the field. We propose a particular ethics strategy--specifically, an ongoing process of collective ethical reflection that the community of ecological researchers, with the cooperation of applied ethicists and philosophers of biology, can use to address the needs we identify. We suggest a particular set of conceptual (in the form of six core values--freedom, fairness, well being, replacement, reduction, and refinement) and analytic (in the forms of decision theoretic software, 1000Minds) tools that, we argue, collectively have the resources to provide an empirically grounded and conceptually complete foundation for an ethics strategy for ecological research. We illustrate our argument with information gathered from a survey of ecologists conducted at the 2013 meeting of the Canadian Society of Ecology and Evolution.

A laboratory medicine residency training program that includes clinical consultation and research.

PubMed

Spitzer, E D; Pierce, G F; McDonald, J M

1990-04-01

We describe a laboratory medicine residency training program that includes ongoing interaction with both clinical laboratories and clinical services as well as significant research experience. Laboratory medicine residents serve as on-call consultants in the interpretation of test results, design of testing strategies, and assurance of test quality. The consultative on-call beeper system was evaluated and is presented as an effective method of clinical pathology training that is well accepted by the clinical staff. The research component of the residency program is also described. Together, these components provide training in real-time clinical problem solving and prepare residents for the changing technological environment of the clinical laboratory. At the completion of the residency, the majority of the residents are qualified laboratory subspecialists and are also capable of running an independent research program.

Massage for Cancer Pain: A Study with University and Hospice Collaboration

PubMed Central

Gorman, Geraldine; Forest, Jeannine; Stapleton, Stephen J.; Hoenig, Noreen A.; Marschke, Michael; Durham, Jan; Suarez, Marie L.

2009-01-01

Conducting scientific research within a clinical practice area presents a variety of challenges. When the specialty area is hospice and palliative care, the collaborative task is particularly daunting. In this paper, we describe an ongoing study being conducted as a partnership between the University of Illinois at Chicago and a large metropolitan hospice organization. Our research is focused on engaging patients and their caregivers in a study measuring the effects of massage on cancer pain. The purpose of this paper is to describe both the lessons learned and the benefits accrued from collaboration between hospice practitioners and academic researchers. We present these process findings as guideposts for others considering end-of-life or palliative care research. Upon completion of the study in 2009, we will disseminate outcome findings in future papers. PMID:19337585

Career Track of Society of University Surgeons Resident Research Award Recipients

PubMed Central

Hassan, Burhan; Bernstam, Elmer; Hines, Joe; Simeone, Diane M.; Weber, Sharon; Geller, David; Evers, B. Mark; Meric-Bernstam, Funda

2015-01-01

Background Society of University Surgeons (SUS) has an ongoing competitive funding program to support research training for residents. We sought to determine the career track of award recipients. Methods SUS resident awardees who completed awards from 1989-2007 were included in the study. Characteristics of awardees and their academic productivity were extracted from curriculum vitae provided by awardees (n=24), or from online sources (n=7). Results The awardees spent an average of 2.7 years (range 1-4) of dedicated research time during residency. Awardees averaged 9.8 publications (range 1-32) with 5.4 as first author (range 1-17) with their mentor within three years of award completion, with an average maximum impact factor of 5.7. Twenty-five residents (81%) pursued fellowships. At an average follow-up of 11.4 years (range 4-22) from end of the award, and 7.2 years (0-18) from end of their clinical training, the awardees had an h-index of 14.5 (2-48). At the time of the study, 26 awardees (84%) were in academic surgery. Of the 23 awardees that had completed surgical training three years earlier or more, 11 (48%) received independent research funding, of which 7 (30%) received R01 or equivalent funding. Conclusions The SUS resident research awardees had a very productive research experience. Although our retrospective study cannot determine causation, the SUS award mechanism delivers on its promise of supporting junior surgeon-scientists that pursue academic careers and establish independent research programs. Further studies are needed to determine how rates of subsequent independent research funding can be improved. PMID:23751805

Influence of Ongoing Task Difficulty and Motivation Level on Children's Prospective Memory in a Chinese Sample.

PubMed

Han, Pi-Guo; Han, Lei; Bian, Yu-Long; Tian, Yu; Xu, Min-Xia; Gao, Feng-Qiang

2017-01-01

Prospective memory (PM) is the process associated with the task of realizing delayed intentions in the future. Researchers distinguish two types of PM, namely time-based PM (tbPM) and event-based PM (ebPM). Experiment 1 investigated the developmental trajectory of 3- to 5-year-old preschool children's PM ability, and the occurrence of delayed retrieval (children execute the PM task in a larger window of opportunity) in both tbPM and ebPM tasks. Results revealed that the 5-year-old children outperformed the 3- and 4-year-old children in PM. Moreover, delayed retrieval was more likely to occur in tbPM task than in ebPM task. In Experiment 2, the influence of ongoing task (OT) difficulty on PM performance was investigated with a sample of 5-year-old children. Results revealed no significant effect of OT difficulty on PM performance. In Experiment 3, we improved children's motivation level to complete the OT, then explored the influence of OT difficulty on children's PM performance. Results revealed that the effect of OT difficulty on PM performance became significant after increasing the children's motivation to complete the OT. These results provide insights into the mechanism of attentional resource allocation in PM tasks and have crucial educational and social implications.

Preceptor/mentor education: a world of possibilities through e-learning technology.

PubMed

Myrick, Florence; Caplan, Wendy; Smitten, Jayne; Rusk, Kerry

2011-04-01

Preceptorship/mentorship is designed to socialize students into the nursing profession, promote their confidence/competence and foster their critical thinking ability. In today's global context, opportunities exist for local, rural, national and international student placements which provide exciting and mutually rewarding preceptorship experiences. Despite the recognized value of those involved in preceptorship/mentorship, however, little progress has been made regarding the development of an infrastructure that effectively supports their ongoing education. This project, piloted from October 2008 to February 2009, leveraged our established research and teaching experience in preceptorship with technologies that allowed us to create an accessible and engaging e-learning space designed to support preceptors in a seamless fashion, improve the quality of the student preceptorship and enhance professional teaching capacity. A purposive sample of 25 preceptors was selected with a total of 18 preceptors successfully completing the five month program. Upon completion, participants were surveyed and individually interviewed. Data analysis revealed the program to be informative, supportive and highly valued. Knowledge derived from this study can: a) further enrich the substantive nature and infrastructure of online preceptor education; and b) contribute to clarifying best practices for preceptor support, facilitation, and ongoing professional development with a view to enhancing the preceptorship experience. Copyright © 2010 Elsevier Ltd. All rights reserved.

Half-century archives of occupational medical data on French nuclear workers: a dusty warehouse or gold mine for epidemiological research?

PubMed

Garsi, Jerome-Philippe; Samson, Eric; Chablais, Laetitia; Zhivin, Sergey; Niogret, Christine; Laurier, Dominique; Guseva Canu, Irina

2014-12-01

This article discusses the availability and completeness of medical data on workers from the AREVA NC Pierrelatte nuclear plant and their possible use in epidemiological research on cardiovascular and metabolic disorders related to internal exposure to uranium. We created a computer database from files on 394 eligible workers included in an ongoing nested case-control study from a larger cohort of 2897 French nuclear workers. For each worker, we collected records of previous employment, job positions, job descriptions, medical visits, and blood test results from medical history. The dataset counts 9,471 medical examinations and 12,735 blood test results. For almost all of the parameters relevant for research on cardiovascular risk, data completeness and availability is over 90%, but it varies with time and improves in the latest time period. In the absence of biobanks, collecting and computerising available good-quality occupational medicine archive data constitutes a valuable alternative for epidemiological and aetiological research in occupational health. Biobanks rarely contain biological samples over an entire worker's carrier and medical data from nuclear industry archives might make up for unavailable biomarkers that could provide information on cardiovascular and metabolic diseases.

Discrepancies between ClinicalTrials.gov recruitment status and actual trial status: a cross-sectional analysis.

PubMed

Jones, Christopher W; Safferman, Michelle R; Adams, Amanda C; Platts-Mills, Timothy F

2017-10-11

To determine the accuracy of the recruitment status listed on ClinicalTrials.gov as compared with the actual trial status. Cross-sectional analysis. Random sample of interventional phase 2-4 clinical trials registered between 2010 and 2012 on ClinicalTrials.gov. For each trial which was listed within ClinicalTrials.gov as ongoing, two investigators performed a comprehensive literature search for evidence that the trial had actually been completed. For each trial listed as completed or terminated early by ClinicalTrials.gov, we compared the date that the trial was actually concluded with the date the registry was updated to reflect the study's conclusion status. Among the 405 included trials, 92 had a registry status indicating that study activity was either ongoing or the recruitment status was unknown. Of these, published results were available for 34 (37%). Among the 313 concluded trials, the median delay between study completion and a registry update reflecting that the study had ended was 141 days (IQR 48-419), with delays of over 1 year present for 29%. In total, 125 trials (31%) either had a listed recruitment status which was incorrect or had a delay of more than 1 year between the time the study was concluded and the time the registry recruitment status was updated. At present, registry recruitment status information in ClinicalTrials.gov is often outdated or wrong. This inaccuracy has implications for the ability of researchers to identify completed trials and accurately characterise all available medical knowledge on a given subject. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Application of Out-of-Plane Warping to Control Rotor Blade Twist

NASA Technical Reports Server (NTRS)

VanWeddingen, Yannick; Bauchau, Olivier; Kottapalli, Sesi; Ozbay, Serkan; Mehrotra, Yogesh

2012-01-01

The goal of this ongoing study is to develop and demonstrate the feasibility of a blade actuation system to dynamically change the twist, and/or the camber, of an airfoil section and, consequently, alter the in-flight aerodynamic loading on the blade for efficient flight control. The required analytical and finite element tools are under development to enable an accurate and comprehensive aeroelastic assessment of the current Full-Blade Warping and 3D Warping Actuated Trailing Edge Flap concepts. The feasibility of the current concepts for swashplateless rotors and higher harmonic blade control is also being investigated. In particular, the aim is to complete the following objectives, some of which have been completed (as noted below) and others that are currently ongoing: i) Develop a Vlasov finite element model and validate against the ABAQUS shell models (completed). ii) Implement the 3D warping actuation concept within the comprehensive analysis code DYMORE. iii) Perform preliminary aeroelastic simulations of blades using DYMORE with 3D warping actuation: a) Investigate the blade behavior under 1 per/rev actuation. Determine whether sufficient twist can be generated and sustained to achieve primary blade control. b) Investigate the behavior of a trailing edge flap configuration under higher harmonic excitations. Determine how much twist can be obtained at the harmonics 2-5 per/rev. iv) Determine actuator specifications such as the power required, load and displacements, and identify the stress and strain distributions in the actuated blades. In general, the completion of Item ii) above will give an additional research capability in rotorcraft dynamics analyses, i.e., the capability to calculate the rotor blade twist due to warping, something that is not currently available in any of the existing comprehensive rotorcraft analyses.

Towards efficient use of research resources: a nationwide database of ongoing primary care research projects in the Netherlands.

PubMed

Kortekaas, Marlous F; van de Pol, Alma C; van der Horst, Henriëtte E; Burgers, Jako S; Slort, Willemjan; de Wit, Niek J

2014-04-01

PURPOSE. Although in the last decades primary care research has evolved with great success, there is a growing need to prioritize the topics given the limited resources available. Therefore, we constructed a nationwide database of ongoing primary care research projects in the Netherlands, and we assessed if the distribution of research topics matched with primary care practice. We conducted a survey among the main primary care research centres in the Netherlands and gathered details of all ongoing primary care research projects. We classified the projects according to research topic, relation to professional guidelines and knowledge deficits, collaborative partners and funding source. Subsequently, we compared the frequency distribution of clinical topics of research projects to the prevalence of problems in primary care practice. We identified 296 ongoing primary care research projects from 11 research centres. Most projects were designed as randomized controlled trial (35%) or observational cohort (34%), and government funded mostly (60%). Thematically, most research projects addressed chronic diseases, mainly cardiovascular risk management (8%), depressive disorders (8%) and diabetes mellitus (7%). One-fifth of the projects was related to defined knowledge deficits in primary care guidelines. From a clinical primary care perspective, research projects on dermatological problems were significantly underrepresented (P = 0.01). This survey of ongoing projects demonstrates that primary care research has a firm basis in the Netherlands, with a strong focus on chronic disease. The fit with primary care practice can improve, and future research should address knowledge deficits in professional guidelines more.

Fate of protocols submitted to a French national funding scheme: a cohort study.

PubMed

Decullier, Evelyne; Huot, Laure; Chapuis, François R

2014-01-01

The fate of clinical research projects funded by a grant has been investigated, but there is no information on the projects which did not receive funding. The fate of these projects is not known: do they apply for and/or receive funding from other sources or are they carried out without specific funding? The aim of the study was to describe all clinical research projects submitted to a French national funding scheme (PHRC 2000) and to assess project initiation, completion and publication status taking into account whether or not they received funding. This study is a retrospective cohort. The initial project characteristics were retrieved from the submission files and follow-up information was collected from the primary investigator. The percentages of projects started, completed and published were studied. A total of 481 projects were studied. Follow-up information was obtained for 366. Overall, 185 projects were initiated (51%); 139 of them were funded by the PHRC 2000 or other sources. The most commonly cited reason for not initiating a project was a lack of funding. Subsequently, 121 of the projects initiated were completed (65%). Accrual difficulties were the main reason cited to explain why studies were stopped prematurely or were still ongoing. Finally, 88 of the completed projects were published (73%). Amongst the completed projects, the only factor explaining publication was the statistical significance of the results. Obtainment of funding was a determining factor for project initiation. However, once initiated, the funding did not influence completion or publication.

Proceedings of the Fourth Glacier Bay Science Symposium

USGS Publications Warehouse

Piatt, John F.; Gende, Scott M.

2007-01-01

Foreword Glacier Bay was established as a National Monument in 1925, in part to protect its unique character and natural beauty, but also to create a natural laboratory to examine evolution of the glacial landscape. Today, Glacier Bay National Park and Preserve is still a place of profound natural beauty and dynamic landscapes. It also remains a focal point for scientific research and includes continuing observations begun decades ago of glacial processes and terrestrial ecosystems. In recent years, research has focused on glacial-marine interactions and ecosystem processes that occur below the surface of the bay. In October 2004, Glacier Bay National Park convened the fourth in a series of science symposiums to provide an opportunity for researchers, managers, interpreters, educators, students and the general public to share knowledge about Glacier Bay. The Fourth Glacier Bay Science Symposium was held in Juneau, Alaska, rather than at the Park, reflecting a desire to maximize attendance and communication among a growing and diverse number of stakeholders interested in science in the park. More than 400 people attended the symposium. Participants provided 46 oral presentations and 41 posters covering a wide array of disciplines including geology, glaciology, oceanography, wildlife and fisheries biology, terrestrial and marine ecology, socio-cultural research and management issues. A panel discussion focused on the importance of connectivity in Glacier Bay research, and keynote speakers (Gary Davis and Terry Chapin) spoke of long-term monitoring and ecological processes. These proceedings include 56 papers from the symposium. A summary of the Glacier Bay Science Plan-itself a subject of a meeting during the symposium and the result of ongoing discussions between scientists and resource managers-also is provided. We hope these proceedings illustrate the diversity of completed and ongoing scientific studies, conducted within the Park. To this end, we invited all presenters to submit brief technical summaries of their work, to capture the gist of their study and its main findings without an overload of details and methodology. We also asked authors to include a few words on the management implications of their work to help bridge the gap between scientists and managers in understanding how specific research questions may translate to management practice. Papers in this volume are laid out by subject matter, from terrestrial and freshwater subjects to glacial-marine geology, to the ecology of marine animals and ending with risk assessment, human impacts and science-management considerations. In summary, we hope the proceedings will serve as a useful reference to completed and ongoing studies in Glacier Bay National Park, and thereby provide park enthusiasts, scientists, and managers with a road map of scientific progress.

EMERGING CONTAMINANTS: AN OVERVIEW OF ON-GOING RESEARCH

EPA Science Inventory

This presentation covers an overview of research on emerging contaminants on-going at

U.S. EPA's National Exposure Research Laboratory in Las Vegas. Due to the

improvements and sophistication of recent analytical instruments, increasing numbers of

chemicals a...

Evaluations of indoor noise criteria systems based on human response

NASA Astrophysics Data System (ADS)

Bowden, Erica E.; Wang, Lily M.

2005-09-01

The goal of this research is to examine human response to background noise, and relate results to indoor noise criteria. In previous work by the authors, subjects completed perception surveys, typing tasks, and proofreading tasks under typical heating, ventilating, and air-conditioning (HVAC) noise conditions. Results were correlated with commonly used indoor noise criteria systems including noise criteria (NC), room criteria (RC) and others. The findings suggested that the types of tasks used and the length of exposure can impact the results. To examine these two issues, the authors conducted a new study in which each test subject completed 38 total hours of testing over multiple days. Subjects were exposed to several background noise exposures over 20, 40, 80, and 240 minute trials. During the trials, subjects completed a variety of performance tasks and answered questions about their perception of the noise, the thermal environment, and various other factors. Findings from this study were used to determine optimum testing conditions for on-going research examining the effects of tonal or fluctuating background noise on performance, annoyance, and spectral perception. Results are being used to evaluate the effectiveness of commonly used indoor noise criteria systems. [Work supported by INCE and ASHRAE.

In silico gene expression profiling in Cannabis sativa.

PubMed

Massimino, Luca

2017-01-01

The cannabis plant and its active ingredients (i.e., cannabinoids and terpenoids) have been socially stigmatized for half a century. Luckily, with more than 430,000 published scientific papers and about 600 ongoing and completed clinical trials, nowadays cannabis is employed for the treatment of many different medical conditions. Nevertheless, even if a large amount of high-throughput functional genomic data exists, most researchers feature a strong background in molecular biology but lack advanced bioinformatics skills. In this work, publicly available gene expression datasets have been analyzed giving rise to a total of 40,224 gene expression profiles taken from cannabis plant tissue at different developmental stages. The resource presented here will provide researchers with a starting point for future investigations with Cannabis sativa .

Drug checking: a potential solution to the opioid overdose epidemic?

PubMed

Bardwell, Geoff; Kerr, Thomas

2018-05-25

North America is experiencing an overdose epidemic driven in part by the proliferation of illicitly-manufactured fentanyl and related analogues. In response, communities are scaling up novel overdose prevention interventions. Included are drug checking technologies. Drug checking technologies aim to identify the contents of illicit drugs. These technologies vary considerably in terms of cost, accuracy, and usability, and while efforts are now underway to implement drug checking programs for people who inject drugs, there remains a lack of rigorous evaluation of their impacts. Given the ongoing overdose crisis and the urgent need for effective responses, research on drug checking should be prioritized. However, while such research should be supported, it should be completed before these technologies are widely implemented.

History of Presolar Grains

NASA Technical Reports Server (NTRS)

Bernatowicz, Thomas J.

2005-01-01

Papers on the History of Presolar Grains. This has been a very productive period in which much of the laboratory work conducted in the previous year and during this funding cycle were brought to completion. In the last year we have published or submitted for peer review 4 research papers, 4 review papers, and 11 abstracts in research areas supported under this grant. Brief synopses of the results of the research papers are presented, followed by short summaries of the topics discussed in the review papers. Several areas of research are of course being actively pursued, and the appended list of abstracts gives citations to this ongoing work. In a paper submitted to the Astrophysical Journal, the results of an investigation into the physical conditions in the mass outflows of asymptotic giant branch (AGB) carbon stars that are required for the formation of micron-sized presolar graphite grains, with and without previously formed internal crystals of titanium carbide (TIC) are reported.

Multidisciplinary Design Investigation of Truss-Braced Wing Aircraft. Phase 4

NASA Technical Reports Server (NTRS)

Grossman, B.; Kapania, R. K.; Mason, W. H.; Schetz, J. A.

2000-01-01

The subject grant was in effect from 7/l/99 to 10/31/99. The objective of this grant was to complete a strut-braced wing study which began, which was in effect from 6/27/96 until 9/15/99. While the initial grant was on-going, we were also under subcontract to Lockheed-Martin, Aerospace Systems Division, Marietta, GA to do additional studies related to the strut-braced wing grant "A Structural and Aerodynamic Investigation of a Strut-Braced Wing Transonic Aircraft Concept", 4/l/98-11/15/98. Lockheed-Martin was under contract to NASA Langley. Finally the research under this grant has led to a joint proposal from NASA Langley, Locheed-Martin, Virginia Tech and NASA Dryden to develop a transonic strut-braced wing demonstration aircraft in response to Flight Research for Revolutionary Aeronautical Concepts (REVCON). This final report summarizes the research done, augmented by the additional concommitant research projects mentioned above.

Informed Consent in Genome-Scale Research: What Do Prospective Participants Think?

PubMed Central

Trinidad, Susan Brown; Fullerton, Stephanie M.; Bares, Julie M.; Jarvik, Gail P.; Larson, Eric B.; Burke, Wylie

2012-01-01

Background To promote effective genome-scale research, genomic and clinical data for large population samples must be collected, stored, and shared. Methods We conducted focus groups with 45 members of a Seattle-based integrated healthcare delivery system to learn about their views and expectations for informed consent in genome-scale studies. Results Participants viewed information about study purpose, aims, and how and by whom study data could be used to be at least as important as information about risks and possible harms. They generally supported a tiered consent approach for specific issues, including research purpose, data sharing, and access to individual research results. Participants expressed a continuum of opinions with respect to the acceptability of broad consent, ranging from completely acceptable to completely unacceptable. Older participants were more likely to view the consent process in relational – rather than contractual – terms, compared with younger participants. The majority of participants endorsed seeking study subjects’ permission regarding material changes in study purpose and data sharing. Conclusions Although this study sample was limited in terms of racial and socioeconomic diversity, our results suggest a strong positive interest in genomic research on the part of at least some prospective participants and indicate a need for increased public engagement, as well as strategies for ongoing communication with study participants. PMID:23493836

Benefits and Harms of Plant-Based Cannabis for Posttraumatic Stress Disorder: A Systematic Review.

PubMed

O'Neil, Maya E; Nugent, Shannon M; Morasco, Benjamin J; Freeman, Michele; Low, Allison; Kondo, Karli; Zakher, Bernadette; Elven, Camille; Motu'apuaka, Makalapua; Paynter, Robin; Kansagara, Devan

2017-09-05

Cannabis is available from medical dispensaries for treating posttraumatic stress disorder (PTSD) in many states of the union, yet its efficacy in treating PTSD symptoms remains uncertain. To identify ongoing studies and review existing evidence regarding the benefits and harms of plant-based cannabis preparations in treating PTSD in adults. MEDLINE, the Cochrane Library, and other sources from database inception to March 2017. English-language systematic reviews, trials, and observational studies with a control group that reported PTSD symptoms and adverse effects of plant-based cannabis use in adults with PTSD. Study data extracted by 1 investigator was checked by a second reviewer; 2 reviewers independently assessed study quality, and the investigator group graded the overall strength of evidence by using standard criteria. Two systematic reviews, 3 observational studies, and no randomized trials were found. The systematic reviews reported insufficient evidence to draw conclusions about benefits and harms. The observational studies found that compared with nonuse, cannabis did not reduce PTSD symptoms. Studies had medium and high risk of bias, and overall evidence was judged insufficient. Two randomized trials and 6 other studies examining outcomes of cannabis use in patients with PTSD are ongoing and are expected to be completed within 3 years. Very scant evidence with medium to high risk of bias. Evidence is insufficient to draw conclusions about the benefits and harms of plant-based cannabis preparations in patients with PTSD, but several ongoing studies may soon provide important results. U.S. Department of Veterans Affairs, Veterans Health Administration, Office of Research and Development, Quality Enhancement Research Initiative. (PROSPERO: CRD42016033623).

A Study of Reflected Sonic Booms Using Airborne Measurements

NASA Technical Reports Server (NTRS)

Kantor, Samuel R.; Cliatt, Larry J.

2017-01-01

In support of ongoing efforts to bring commercial supersonic flight to the public, the Sonic Booms in Atmospheric Turbulence (SonicBAT) flight test conducted at NASA Armstrong Flight Research Center. During this test, airborne sonic boom measurements were made using an instrumented TG-14 motor glider, called the Airborne Acoustic Measurement Platform (AAMP).During the flight program, the AAMP was consistently able to measure the sonic boom wave that was reflected off of the ground, in addition to the incident wave, resulting in the creation of a completely unique data set of airborne sonic boom reflection measurements.

Understanding beach health throughout the Great Lakes -- continuing research

USGS Publications Warehouse

,

2012-01-01

The overall mission of U.S. Geological Survey (USGS) Beach Health Initiative is to provide science-based information and methods that will allow beach managers to more accurately make beach closure and advisory decisions, understand the sources and physical processes affecting beach contaminants, and understand how science-based information can be used to mitigate and restore beaches and protect the public. The USGS, in collaboration with many Federal, State, and local agencies and universities, has conducted research on beach-health issues in the Great Lakes Region for more than a decade. The work consists of four science elements that align with the initiative's mission: real-time assessments of water quality; coastal processes; pathogens and source tracking; and data analysis, interpretation, and communication. The ongoing or completed research for each of these elements is described in this fact sheet.

The Structure and Function of Non-Collagenous Bone Proteins

NASA Technical Reports Server (NTRS)

Hook, Magnus; McQuillan, David J.

1997-01-01

The research done under the cooperative research agreement for the project titled 'The structure and function of non-collagenous bone proteins' represented the first phase of an ongoing program to define the structural and functional relationships of the principal noncollagenous proteins in bone. An ultimate goal of this research is to enable design and execution of useful pharmacological compounds that will have a beneficial effect in treatment of osteoporosis, both land-based and induced by long-duration space travel. The goals of the now complete first phase were as follows: 1. Establish and/or develop powerful recombinant protein expression systems; 2. Develop and refine isolation and purification of recombinant proteins; 3. Express wild-type non-collagenous bone proteins; 4. Express site-specific mutant proteins and domains of wild-type proteins to enhance likelihood of crystal formation for subsequent solution of structure.

Career track of Society of University Surgeons Resident Research Award recipients.

PubMed

Hassan, Burhan; Bernstam, Elmer; Hines, O Joe; Simeone, Diane M; Weber, Sharon M; Geller, David A; Evers, B Mark; Meric-Bernstam, Funda

2013-11-01

The Society of University Surgeons (SUS) has an ongoing competitive funding program to support research training for residents. We sought to determine the career track of award recipients. We included in the study SUS resident awardees who completed awards from 1989-2007. Characteristics of awardees and their academic productivity were extracted from curriculum vitae provided by awardees (n = 24), or from online sources (n = 7). Awardees spent an average of 2.7 y (range, 1-4 y) of dedicated research time during residency. Awardees averaged 9.8 publications (range, 1-32), with 5.4 as first author (range, 1-17), with their mentor within 3 y of award completion, with an average maximum impact factor of 5.7. A total of 25 residents (81%) pursued fellowships. At an average follow-up of 11.4 y (range, 4-22 y) from the end of the award and 7.2 y (range, 0-18 y) from end of clinical training, awardees had a Hirsch index of 14.5 (range, 2-48). At the time of the study, 26 awardees (84%) were in academic surgery. Of the 23 awardees who had completed surgical training ≥ 3 y earlier, 11 (48%) received independent research funding, seven of whom (30%) received R01 or equivalent funding. The SUS resident research awardees had a productive research experience. Although our retrospective study cannot determine causation, the SUS award mechanism delivers on its promise of supporting junior surgeon-scientists who pursue academic careers and establish independent research programs. Further studies are needed to determine how rates of subsequent independent research funding can be improved. Copyright © 2013 Elsevier Inc. All rights reserved.

Ophthalmology and vision science research: Part 3: avoiding writer's block--understanding the ABCs of a good research paper.

PubMed

McGhee, Charles N J; Gilhotra, Amardeep K

2005-12-01

Completion of a scientific manuscript for submission to a peer-reviewed journal is a daunting task for clinicians and scientists early in their careers. In an ongoing series, this third article is the first of 2 related articles that deal with the basics of producing a high-quality research manuscript. Although ophthalmology and vision science are the principal focus of this series, the general concepts essential to producing a quality manuscript are applicable to diverse fields of research. This article highlights the exponential growth in the scientific literature over the past 40 years, considers why it is important to publish completed research, and discusses the necessity of identifying the key messages of the research, and their context, in relation to the published literature. The ethics of publishing biomedical research and scientific misconduct, such as duplicate publication or plagiarism, are outlined. To avoid later conflict, there is a critical need for coworkers to carefully address authorship order and inclusion early in the manuscript process. Internationally agreed guidelines are identified to guide this process. The importance of choosing the correct journal for a specific article and the nature of basic citation indices are discussed. The article concludes by elaborating and contrasting different scientific writing styles and emphasizing the considerable importance of developing a representative title and applying clarity and appropriate structure to the abstract.

Engaging community volunteers in participatory action research in Tāmaki community of Auckland, New Zealand.

PubMed

Andajani-Sutjahjo, Sari; Liew, Theresa C H; Smith, John F; Esekielu, Iutita; Mason, Gabrielle; Tariu, Imele

2018-04-01

This article discusses the experiences of community volunteers' participation in a community-based participatory research project in Tāmaki, a low socio-economic and ethnically diverse suburban community within greater Auckland City, New Zealand. In the Tāmaki Community Action Research project, community volunteers were recruited and trained to conduct random household surveys (RHS) and asset mapping commissioned by community groups and government agencies in that area. The volunteers were involved in planning, coordination and ongoing governance of the project and ∼70 residents and local university students participated at different stages of the 2-year project. Over 600 RHS were completed and the volunteers' experiences were recorded in field notes, informal group discussions, daily team meetings and individual interviews and form the basis of this article. Only their experiences are discussed here, not the survey results which will be presented elsewhere. The project reflected the inherent asset-rich nature of the community via examples of individual volunteer empowerment and collective social/community capacity building. Volunteers increased their interpersonal and organizational skills, their understanding of the complexity of their community's logistics and cultural diversity, and gained an increased sense of community purpose and commitment. There was very strong endorsement of culturally sensitive research practice to recognize cultural differences and to engage productively within their richly ethnically diverse community. Full community volunteer participation in the project's governance (i.e. through design, training, implementation and ongoing consultation/management phases) was considered key to sustaining the life of project.

NASA and The Semantic Web

NASA Technical Reports Server (NTRS)

Ashish, Naveen

2005-01-01

We provide an overview of several ongoing NASA endeavors based on concepts, systems, and technology from the Semantic Web arena. Indeed NASA has been one of the early adopters of Semantic Web Technology and we describe ongoing and completed R&D efforts for several applications ranging from collaborative systems to airspace information management to enterprise search to scientific information gathering and discovery systems at NASA.

The SWITCH-ON Virtual Water-Science Laboratory

NASA Astrophysics Data System (ADS)

Arheimer, Berit; Boot, Gerben; Calero, Joan; Ceola, Serena; Gyllensvärd, Frida; Hrachowitz, Markus; Little, Lorna; Montanari, Alberto; Nijzink, Remko; Parajka, Juraj; Wagener, Thorsten

2017-04-01

The SWITCH-ON Virtual Water-Science Laboratory (VWSL) aims to facilitate collaboration and support reproducible experiments in water research. The goal is to overcome geographical distance for comparative hydrology and increase transparency when using computational tools in hydrological sciences. The VWSL gives access to open data through dedicated software tools for data search and upload, and helps creating collaborative protocols for joint experiments in the virtual environment. The VWSL will help scientists with: • Cooperation around the world - straightforward connections with other scientists in comparative analyses and collaboration, as a mean to accelerate scientific advance in hydrology. • Repeatability of experiments -thorough review of a large variety of numerical experiments, which is a foundational principle in scientific research, and improvement of research standards. • New forms of scientific research - by using online 'living' protocols, scientists you can elaborate ideas incrementally with a large group of colleagues and share data, tools, models, etc. in open science. The VWSL was developed within the EU project "Sharing Water Information to Tackle Changes in Hydrology - for Operational Needs" (Grant agreement No 603587). Visitors can choose to Define, Participate or Review experiments by clicking the start buttons (http://www.switch-on-vwsl.eu/). Anyone can view protocols without log-in (that's important for Open Science) - but to create, participate and edit protocols, you need to Log-in for security reasons. During the work process, the protocol is moved from one view to another as the experiment evolves from idea, to on-going, to be completed. The users of the Lab also get access to useful tools for running collaborative experiments, for instance: Open data Search, Data (and metadata) Upload, and Create Protocol tools. So far, eight collaborative experiments have been completed in the VWSL and resulted in research papers (published or submitted), and there are currently four on-going experiments, which also involves external participants, not paid by the project. The VWSL is now launched and open to everyone but it will be continuously developed and sustained also after the project. This presentation will give an on-line demonstration of the major features of the present VWSL and discuss some future visions and major challenges in this e-infrastructure.

Detecting ongoing intimate partner violence in the emergency department using a simple 4-question screen: the OVAT.

PubMed

Ernst, Amy A; Weiss, Steven J; Cham, Elaine; Hall, Louise; Nick, Todd G

2004-06-01

We wanted to prospectively evaluate the use of a brief screening tool for ongoing intimate partner violence (IPV), the OVAT, and to validate this tool against the present Index of Spouse Abuse (ISA). The design was a prospective survey during randomized 4-hour shifts in an urban emergency department setting. The scale consists of four questions developed based on our previous work. The ISA was compared as the gold standard for detection of present (ongoing) IPV. Of 362 eligible patients presenting during 75 randomized 4-hour shifts, 306 (85%) completed the study. The prevalence of ongoing IPV using the OVAT was 31% (95% CI 26% to 36%). For the ISA, the prevalence was 20% (95% CI 16% to 25%). Compared with the ISA, the sensitivity of the OVAT in detecting ongoing IPV was 86%, specificity 83%, negative predictive value 96%, positive predictive value 56%, with an accuracy of 84%. In conclusion, four brief questions can detect ongoing IPV to aid in identifying the victim.

Assessing the extent to which current clinical research is consistent with patient priorities: a scoping review using a case study in patients on or nearing dialysis.

PubMed

Jun, Min; Manns, Braden; Laupacis, Andreas; Manns, Liam; Rehal, Bhavdeep; Crowe, Sally; Hemmelgarn, Brenda R

2015-01-01

There is growing acknowledgement that engaging patients to identify their research priorities is important. Using a case study of patients on or nearing dialysis, we sought to assess the extent to which recently completed and ongoing clinical research was consistent with priorities identified by patients, caregivers, and clinicians. Over a 4-year sampling frame (January 2010 to December 2013), we systematically searched the medical literature (top 5 nephrology and top 10 general medicine journals accessed through MEDLINE via Ovid), international randomized controlled trial (RCT) registries, and national government and kidney research funding organizations (Canada, U.S., Australia, and U.K.) for published clinical studies, registered RCTs, and funded clinical studies, respectively. Published clinical studies, registered RCTs, and funded clinical studies were categorized as to whether or not they were consistent with the top 10 research priorities identified by patients, their caregivers, and clinicians in a recent comprehensive research priority setting exercise. The search yielded 4293 published articles, 688 RCTs, and 70 funded studies, of which 1116 articles, 315 RCTs, and 70 funded studies were eligible for inclusion. Overall 194 published studies (17.4 %), 71 RCTs (22.5 %), and 15 funded studies (21.4 %) included topics consistent with the top 10 research priorities identified by patients. Four of the top 10 research priorities, including strategies to improve the management of itching, increase access to kidney transplantation, assess the psychosocial impact of kidney failure, and determine the effects of dietary restriction received virtually no attention. The top 10 priorities we used to categorize included studies were identified by Canadian patients, caregivers, and clinicians. The top research priorities may vary across different countries. The proportion of published studies that are consistent with the top 10 priorities could be different in nephrology journals with lower impact factors. Studies related to kidney transplantation and the psychosocial impact of kidney failure may have been published in journals not included in our search strategy. The majority of recently completed or ongoing clinical studies in patients on or nearing dialysis do not address the top research priorities of patients, raising concerns that current clinical research may not be meeting the needs of the ultimate consumer, in this case, patients on or nearing dialysis. Greater involvement of patients in research is required to bridge the gap between research and patients' needs.

Thinking about the nature of research findings: a hermeneutic phenomenological perspective.

PubMed

Greatrex-White, Sheila

2008-12-01

Written in response to an ongoing process of reflexivity, I deconstruct the findings of a recently completed qualitative hermeneutic phenomenological research study which was designed to answer the question: "How is study abroad manifest in the experience of nursing students?" The purpose is to assist and urge other researchers to locate their research, themselves and their research participants more transparently in the social and cultural worlds within which they move and are a part. Following a sketch of the research study upon which the paper is based, the relationships between structure, agency, researched and researcher are explored within a hermeneutic phenomenological framework. In particular, I relate some of the challenges encountered through reflections on specific aspects of the research process. I conclude that research findings might best be understood as being a dynamic and complex, two-way constructed interpretation of phenomena involving both structure and agency. I proceed from the stance that the discursive and the emotional, the artistic and the scientific, need to be balanced partners. Where this relationship is harmonious, intellectual ability increases leading to better meaning making, better decisions and greater understanding.

Uncertainty in Action: Observing Information Seeking within the Creative Processes of Scholarly Research

ERIC Educational Resources Information Center

Anderson, Theresa Dirndorfer

2006-01-01

Introduction: This paper discusses the role uncertainty plays in judgments of the meaning and significance of ideas and texts encountered by scholars in the context of their ongoing research activities. Method: Two experienced scholars were observed as part of a two-year ethnographic study of their ongoing research practices. Layered…

Quality Matters™: An Educational Input in an Ongoing Design-Based Research Project

ERIC Educational Resources Information Center

Adair, Deborah; Shattuck, Kay

2015-01-01

Quality Matters (QM) has been transforming established best practices and online education-based research into an applicable, scalable course level improvement process for the last decade. In this article, the authors describe QM as an ongoing design-based research project and an educational input for improving online education.

Mapping the organizational culture research in nursing: a literature review.

PubMed

Scott-Findlay, Shannon; Estabrooks, Carole A

2006-12-01

This paper reports a critical review of nursing organizational culture research studies with the objectives of: (1) reviewing theoretical and methodological characteristics of the studies and (2) drawing inferences specific to the state of knowledge in this field. Organizational culture is regarded as significant in influencing research use in clinical practice yet it is not understood how culture shapes practitioners' behaviours. Only one review of this empirical literature in nursing has been completed. Using selected computerized databases, published nursing research studies in English that examine organizational culture were accessed. Organizational culture studies were categorized using Hatch's three perspectives on organizational culture: (1) modern, (2) symbolic-interpretive and (3) postmodern. The review was conducted in 2005. Twenty-nine studies were in the final data set. Results pointed to variations in cultural definitions and incorporation of organizational sciences theory. In classifying the studies, modern perspectives dominated (n = 22), symbolic-interpretive approaches were an emerging group (n = 6) and one study was unclassifiable. Our results expand current cultural instrument reviews by pinpointing tools that have been previously overlooked and by identifying ongoing theoretical and methodological challenges for researchers. An exclusive reliance on modernistic approaches in organizational culture research cannot yield a complete understanding of the phenomenon. Rather, the field could benefit from a variety of cultural approaches. In a similar vein, researchers need to be mindful of the terminology and the unit of analysis they use in their research, as these are the two largest research challenges.

Apoptosis: a four-week laboratory investigation for advanced molecular and cellular biology students.

PubMed

DiBartolomeis, Susan M; Moné, James P

2003-01-01

Over the past decade, apoptosis has emerged as an important field of study central to ongoing research in many diverse fields, from developmental biology to cancer research. Apoptosis proceeds by a highly coordinated series of events that includes enzyme activation, DNA fragmentation, and alterations in plasma membrane permeability. The detection of each of these phenotypic changes is accessible to advanced undergraduate cell and molecular biology students. We describe a 4-week laboratory sequence that integrates cell culture, fluorescence microscopy, DNA isolation and analysis, and western blotting (immunoblotting) to follow apoptosis in cultured human cells. Students working in teams chemically induce apoptosis, and harvest, process, and analyze cells, using their data to determine the order of events during apoptosis. We, as instructors, expose the students to an environment closely simulating what they would encounter in an active cell or molecular biology research laboratory by having students coordinate and perform multiple tasks simultaneously and by having them experience experimental design using current literature, data interpretation, and analysis to answer a single question. Students are assessed by examination of laboratory notebooks for completeness of experimental protocols and analysis of results and for completion of an assignment that includes questions pertaining to data interpretation and apoptosis.

Predictive probability methods for interim monitoring in clinical trials with longitudinal outcomes.

PubMed

Zhou, Ming; Tang, Qi; Lang, Lixin; Xing, Jun; Tatsuoka, Kay

2018-04-17

In clinical research and development, interim monitoring is critical for better decision-making and minimizing the risk of exposing patients to possible ineffective therapies. For interim futility or efficacy monitoring, predictive probability methods are widely adopted in practice. Those methods have been well studied for univariate variables. However, for longitudinal studies, predictive probability methods using univariate information from only completers may not be most efficient, and data from on-going subjects can be utilized to improve efficiency. On the other hand, leveraging information from on-going subjects could allow an interim analysis to be potentially conducted once a sufficient number of subjects reach an earlier time point. For longitudinal outcomes, we derive closed-form formulas for predictive probabilities, including Bayesian predictive probability, predictive power, and conditional power and also give closed-form solutions for predictive probability of success in a future trial and the predictive probability of success of the best dose. When predictive probabilities are used for interim monitoring, we study their distributions and discuss their analytical cutoff values or stopping boundaries that have desired operating characteristics. We show that predictive probabilities utilizing all longitudinal information are more efficient for interim monitoring than that using information from completers only. To illustrate their practical application for longitudinal data, we analyze 2 real data examples from clinical trials. Copyright © 2018 John Wiley & Sons, Ltd.

Influence of Ongoing Task Difficulty and Motivation Level on Children’s Prospective Memory in a Chinese Sample

PubMed Central

Han, Pi-guo; Han, Lei; Bian, Yu-long; Tian, Yu; Xu, Min-xia; Gao, Feng-qiang

2017-01-01

Prospective memory (PM) is the process associated with the task of realizing delayed intentions in the future. Researchers distinguish two types of PM, namely time-based PM (tbPM) and event-based PM (ebPM). Experiment 1 investigated the developmental trajectory of 3- to 5-year-old preschool children’s PM ability, and the occurrence of delayed retrieval (children execute the PM task in a larger window of opportunity) in both tbPM and ebPM tasks. Results revealed that the 5-year-old children outperformed the 3- and 4-year-old children in PM. Moreover, delayed retrieval was more likely to occur in tbPM task than in ebPM task. In Experiment 2, the influence of ongoing task (OT) difficulty on PM performance was investigated with a sample of 5-year-old children. Results revealed no significant effect of OT difficulty on PM performance. In Experiment 3, we improved children’s motivation level to complete the OT, then explored the influence of OT difficulty on children’s PM performance. Results revealed that the effect of OT difficulty on PM performance became significant after increasing the children’s motivation to complete the OT. These results provide insights into the mechanism of attentional resource allocation in PM tasks and have crucial educational and social implications. PMID:28203212

Overview of Ongoing NRMRL GI Research

EPA Science Inventory

This presentation is an overview of ongoing NRMRL Green Infrastructure research and addresses the question: What do we need to know to present a cogent estimate of the value of Green Infrastructure? Discussions included are: stormwater well study, rain gardens and permeable su...

Wireless Crew Communication Feasibility Assessment

NASA Technical Reports Server (NTRS)

Archer, Ronald D.; Romero, Andy; Juge, David

2016-01-01

Ongoing discussions with crew currently onboard the ISS as well as the crew debriefs from completed ISS missions indicate that issues associated with the lack of wireless crew communication results in increased crew task completion times and lower productivity, creates cable management issues, and increases crew frustration.

Supporting the Thesis Writing Process of International Research Students through an Ongoing Writing Group

ERIC Educational Resources Information Center

Li, Linda Y.; Vandermensbrugghe, Joelle

2011-01-01

Evidence from research suggests writing support is particularly needed for international research students who have to tackle the challenges of thesis writing in English as their second language in Western academic settings. This article reports the development of an ongoing writing group to support the thesis writing process of international…

Incubating the research independence of a medical scientist training program graduate: a case study.

PubMed

Dzirasa, Kafui; Krishnan, Ranga R; Williams, R Sanders

2015-02-01

Physician-scientists play a critical role in discovering new biological knowledge and translating findings into medical practices that can improve clinical outcomes. Collectively, the National Institutes of Health (NIH) and its affiliated Medical Scientist Training Programs (MSTPs) invest upwards of $500,000 to fully train each of the 900+ MD/PhD students enrolled in these programs. Nevertheless, graduates face the challenges of navigating fragmented intervals of clinical training and research engagement, reinitiating research upon completing their residencies, managing financial pressures, and competing for funding following what is typically four or more years of research inactivity. Together, these barriers contribute to the high attrition rate of MSTP graduates from research careers. The authors designed and implemented (2009-2014), for a single trainee, an alternative postgraduate training model characterized by early research engagement, strategic mentoring, unyoked clinical and research milestones, and dedicated financial support. The pilot training experiment was so successful that the trainee secured an NIH project grant and completed his transition to research independence 3.5 years after starting the experimental training schedule-nearly 9 years earlier (based on age) than is typical for MD/PhDs transitioning from mentored to independent research. This success has demonstrated that unyoking research engagement from conventional calendar-based clinical training milestones is a feasible, effective means of incubating research independence in MSTP graduates. The authors encourage the design and application of similar unconventional approaches that interweave residency training with ongoing research activity for appropriate candidates, especially in subspecialties with increased MSTP graduate enrollment.

Research on pathogens at Great Lakes beaches: sampling, influential factors, and potential sources

USGS Publications Warehouse

,

2013-01-01

The overall mission of this work is to provide science-based information and methods that will allow beach managers to more accurately make beach closure and advisory decisions, understand the sources and physical processes affecting beach contaminants, and understand how science-based information can be used to mitigate and restore beaches and protect the public. The U.S. Geological Survey (USGS), in collaboration with many Federal, State, and local agencies and universities, has conducted research on beach health issues in the Great Lakes Region for more than a decade. The work consists of four science elements that align with the USGS Beach Health Initiative Mission: real-time assessments of water quality; coastal processes; pathogens and source tracking; and data analysis, interpretation, and communication. The ongoing or completed research for the pathogens and source tracking topic is described in this fact sheet.

COTSAT Small Spacecraft Cost Optimization for Government and Commercial Use

NASA Technical Reports Server (NTRS)

Swank, Aaron J.; Bui, David; Dallara, Christopher; Ghassemieh, Shakib; Hanratty, James; Jackson, Evan; Klupar, Pete; Lindsay, Michael; Ling, Kuok; Mattei, Nicholas;

Utilizing Remote Sensing Data to Ascertain Soil Moisture Applications and Air Quality Conditions

NASA Technical Reports Server (NTRS)

Leptoukh, Gregory; Kempler, Steve; Teng, William; Friedl, Lawrence; Lynnes, Chris

2009-01-01

Recognizing the significance of NASA remote sensing Earth science data in monitoring and better understanding our planet's natural environment, NASA Earth Applied Sciences has implemented the 'Decision Support Through Earth Science Research Results' program. Several applications support systems through collaborations with benefiting organizations have been implemented. The Goddard Earth Sciences Data and Information Services Center (GES DISC) has participated in this program on two projects (one complete, one ongoing), and has had opportune ad hoc collaborations utilizing NASA Earth science data. GES DISC's understanding of Earth science missions and resulting data and information enables the GES DISC to identify challenges that come with bringing science data to research applications. In this presentation we describe applications research projects utilizing NASA Earth science data and a variety of resulting GES DISC applications support system project experiences. In addition, defining metrics that really evaluate success will be exemplified.

Permethrin Exposure Dosimetry: Biomarkers and Modifiable Factors

DTIC Science & Technology

2015-08-01

ongoing communication with the US Army Center for Initial Military Training (CIMT) has taken place, initiating in August 2014. The PI briefed the DCG ...2016, ongoing communication with National Guard Bureau has taken place, initiating in April 2015. o With DCG -IMT approval (see Task 3 below...September 2015. TASK 3 Study 1 site approval [COMPLETE] o DCG -IMT Approval Memorandum, 1 June 2015. Approval process identified Ft. Sill as the location

Hard tissue regeneration using bone substitutes: an update on innovations in materials

PubMed Central

Sarkar, Swapan Kumar

2015-01-01

Bone is a unique organ composed of mineralized hard tissue, unlike any other body part. The unique manner in which bone can constantly undergo self-remodeling has created interesting clinical approaches to the healing of damaged bone. Healing of large bone defects is achieved using implant materials that gradually integrate with the body after healing is completed. Such strategies require a multidisciplinary approach by material scientists, biological scientists, and clinicians. Development of materials for bone healing and exploration of the interactions thereof with the body are active research areas. In this review, we explore ongoing developments in the creation of materials for regenerating hard tissues. PMID:25995658

Huminite reflectance measurements of Paleocene and Upper Cretaceous coals from borehole cuttings, Zavala and Dimmit counties, South Texas

USGS Publications Warehouse

Hackley, Paul C.; Hook, Robert W.; Warwick, Peter D.

2005-01-01

The reflectance of huminite in 19 cuttings samples was determined in support of ongoing investigations into the coal bed methane potential of subsurface Paleocene and Upper Cretaceous coals of South Texas. Coal cuttings were obtained from the Core Research Center of the Bureau of Economic Geology, The University of Texas at Austin. Geophysical logs, mud-gas logs, driller's logs, completion cards, and scout tickets were used to select potentially coal-bearing sample suites and to identify specific sample depths. Reflectance measurements indicate coals of subbituminous rank are present in a wider area in South Texas than previously recognized.

Patient safety, quality of care, and knowledge translation in the intensive care unit.

PubMed

Needham, Dale M

2010-07-01

A large gap exists between the completion of clinical research demonstrating the benefit of new treatment interventions and improved patient outcomes resulting from implementation of these interventions as part of routine clinical practice. This gap clearly affects patient safety and quality of care. Knowledge translation is important for addressing this gap, but evaluation of the most appropriate and effective knowledge translation methods is still ongoing. Through describing one model for knowledge translation and an example of its implementation, insights can be gained into systematic methods for advancing the implementation of evidence-based interventions to improve safety, quality, and patient outcomes.

Hard tissue regeneration using bone substitutes: an update on innovations in materials.

PubMed

Sarkar, Swapan Kumar; Lee, Byong Taek

2015-05-01

Bone is a unique organ composed of mineralized hard tissue, unlike any other body part. The unique manner in which bone can constantly undergo self-remodeling has created interesting clinical approaches to the healing of damaged bone. Healing of large bone defects is achieved using implant materials that gradually integrate with the body after healing is completed. Such strategies require a multidisciplinary approach by material scientists, biological scientists, and clinicians. Development of materials for bone healing and exploration of the interactions thereof with the body are active research areas. In this review, we explore ongoing developments in the creation of materials for regenerating hard tissues.

Barium Tagging from nEXO Using Resonance Ionization Spectroscopy

NASA Astrophysics Data System (ADS)

Twelker, K.; Kravitz, S.

nEXO is a 5-ton liquid enriched-xenon time projection chamber (TPC) to search for neutrinoless double-beta decay, designed to have the sensitivity to completely probe the inverted mass hierarchy of Majorana neutrinos. The detector will accommodate-as a background reduction technique-a system to recover and identify the barium decay product. This upgrade will allow a background-free measurement of neutrinoless double-beta decay and increase the half-life sensitivity of the experiment by at least one order of magnitude. Ongoing research and development includes a system to test barium extraction from liquid xenon using surface adsorption and Resonance Ionization Spectroscopy (RIS).

28 CFR 91.58 - Timing of the environmental review process.

Code of Federal Regulations, 2010 CFR

2010-07-01

... decisions or new commitments of resources can be made on these projects by the State or local entity that... specifications; or (5) Purchasing property. (e) Ongoing or completed construction projects. For grant-funded... been done, making every effort to limit disruption to projects under construction. For completed grant...

Pain, health-related quality of life and health care utilization after inpatient surgery: A pilot study

PubMed Central

VanDenKerkhof, Elizabeth G; Hopman, Wilma M; Towheed, Tanveer; Wilson, Rosemary; Murdoch, John; Rimmer, Michael; Stutzman, Sherri Schmidt; Tod, Debbie; Dagnone, Vico; Goldstein, David H

2006-01-01

BACKGROUND Little is known about pain-related outcomes in surgical inpatients after discharge from the hospital. An ongoing risk and outcomes monitoring system would provide valuable feedback to improve the quality of patient care. OBJECTIVES The purpose of the present pilot study was to describe postoperative pain, medication use, health care utilization and health-related quality of life (HRQOL) immediately and four weeks after surgery; merge clinically captured data with Web-based follow-up data; and examine patients’ willingness to complete Web-based health questionnaires. METHODS One hundred two consecutive surgical inpatients were approached for participation. Perioperative data were abstracted from the acute pain management service clinical database and linked to follow-up data captured four weeks postoperatively. RESULTS Follow-up questionnaires were completed by 88 participants. Clinical assessment data were successfully linked to Web-based follow-up data. Average pain intensity (3.7) four weeks following discharge fell just short of the acute pain management service active pain score of 3.9. At four weeks, all 88 participants reported significantly impaired HRQOL, 36 were still taking pain medications and 15 had visited an emergency room. Two-thirds of the participants had access to the Internet at home and approximately one-half were willing to complete on-line health questionnaires. DISCUSSION The study indicates that it is feasible to link clinical and research data, and shows a significant burden of pain and reduced HRQOL in the weeks following discharge. This approach to converting clinically captured data into meaningful information about surgical outcomes is valuable in the development of an ongoing risk and outcomes monitoring system. PMID:16511613

Research utilization in the building industry: decision model and preliminary assessment

DOE Office of Scientific and Technical Information (OSTI.GOV)

Watts, R.L.; Johnson, D.R.; Smith, S.A.

1985-10-01

The Research Utilization Program was conceived as a far-reaching means for managing the interactions of the private sector and the federal research sector as they deal with energy conservation in buildings. The program emphasizes a private-public partnership in planning a research agenda and in applying the results of ongoing and completed research. The results of this task support the hypothesis that the transfer of R and D results to the buildings industry can be accomplished more efficiently and quickly by a systematic approach to technology transfer. This systematic approach involves targeting decision makers, assessing research and information needs, properly formatingmore » information, and then transmitting the information through trusted channels. The purpose of this report is to introduce elements of a market-oriented knowledge base, which would be useful to the Building Systems Division, the Office of Buildings and Community Systems and their associated laboratories in managing a private-public research partnership on a rational systematic basis. This report presents conceptual models and data bases that can be used in formulating a technology transfer strategy and in planning technology transfer programs.« less

Using health technology assessment to identify gaps in evidence and inform study design for comparative effectiveness research.

PubMed

Tunis, Sean R; Turkelson, Charles

2012-12-01

Health technology assessment (HTA) is primarily used as a tool to ensure that clinical and policy decisions are made with the benefit of a systematic analysis of all completed research. This article describes the progress and potential for HTA reports to improve the quality and relevance of future research and to better serve the information needs of patients, clinicians, payers, and other decision makers. We conducted a review of the current published literature and working papers describing past, ongoing, and future initiatives that rely on HTA reports to identify gaps in evidence and improve the design of future research. Although still in a developmental stage, significant progress is under way to improve methods for using HTA reports for the systematic identification of research gaps, prioritization of future research, and improvement of study designs. Several well-defined frameworks have been developed to assist those who produce HTA to become more effective in these additional domains of work. A recurring element of this work is the importance of meaningfully involving stakeholders in the process of defining future research needs and designing studies to address them. Patients, clinicians, and payers are important audiences for completed research and are now recognized as serving an important role in determining what future research is needed. There are substantial opportunities to improve the quality, relevance, and efficiency of clinical research. Recent efforts are beginning to demonstrate the potential to build on the work invested in developing HTA reports to provide a roadmap toward these objectives.

Geoparsing text for characterizing urban operational environments through machine learning techniques

NASA Astrophysics Data System (ADS)

Garfinkle, Noah W.; Selig, Lucas; Perkins, Timothy K.; Calfas, George W.

2017-05-01

Increasing worldwide internet connectivity and access to sources of print and open social media has increased near realtime availability of textual information. Capabilities to structure and integrate textual data streams can contribute to more meaningful representations of operational environment factors (i.e., Political, Military, Economic, Social, Infrastructure, Information, Physical Environment, and Time [PMESII-PT]) and tactical civil considerations (i.e., Areas, Structures, Capabilities, Organizations, People and Events [ASCOPE]). However, relying upon human analysts to encode this information as it arrives quickly proves intractable. While human analysts possess an ability to comprehend context in unstructured text far beyond that of computers, automated geoparsing (the extraction of locations from unstructured text) can empower analysts to automate sifting through datasets for areas of interest. This research evaluates existing approaches to geoprocessing as well as initiating the research and development of locally-improved methods of tagging parts of text as possible locations, resolving possible locations into coordinates, and interfacing such results with human analysts. The objective of this ongoing research is to develop a more contextually-complete picture of an area of interest (AOI) including human-geographic context for events. In particular, our research is working to make improvements to geoparsing (i.e., the extraction of spatial context from documents), which requires development, integration, and validation of named-entity recognition (NER) tools, gazetteers, and entity-attribution. This paper provides an overview of NER models and methodologies as applied to geoparsing, explores several challenges encountered, presents preliminary results from the creation of a flexible geoparsing research pipeline, and introduces ongoing and future work with the intention of contributing to the efficient geocoding of information containing valuable insights into human activities in space.

Genocide Rape Trauma: A Conceptual Framework for Understanding the Psychological Suffering of Rwandan Survivors.

PubMed

Mukamana, Donatilla; Collins, Anthony; Rosa, William E

2018-05-01

In 1994, the Rwandan genocide claimed the lives of approximately 1 million Tutsi and moderate Hutu citizens. Systematic rape was a strategic component of the Hutu extremist plan to eradicate the Tutsi minority population. This involved collective and repeated sexual assaults with brutal violence, public humiliation, and torture. This article maps the ongoing psychological impact on Rwandan genocide rape survivors and identifies implications for international nursing practice. The research formalizes their narratives, identifying a number of interconnected elements that combine to produce myriad forms of chronic psychological suffering in the Rwandan context. This work in turn reveals the specific needs of these survivors that may be addressed by nursing. It allows nurses, as experts in managing the human responses to health and illness, to develop a more complete understanding of psychological suffering as it pertains to vulnerable populations during and in the wake of extreme social conflict. This clarifies the roles of nurse educators, clinicians, and policy advocates as key agents in providing genocide rape survivors with the resources and expertise needed to effectively manage their ongoing trauma.

Connectomes as constitutively epistemic objects: Critical perspectives on modeling in current neuroanatomy.

PubMed

Haueis, Philipp; Slaby, Jan

2017-01-01

The term "connectome" is commonly taken to describe a complete map of neural connections in a nervous system of a given species. This chapter provides a critical perspective on the role of connectomes in neuroscientific practice and asks how the connectomic approach fits into a larger context in which network thinking permeates technology, infrastructure, social life, and the economy. In the first part of this chapter, we argue that, seen from the perspective of ongoing research, the notion of connectomes as "complete descriptions" is misguided. Our argument combines Rachel Ankeny's analysis of neuroanatomical wiring diagrams as "descriptive models" with Hans-Jörg Rheinberger's notion of "epistemic objects," i.e., targets of research that are still partially unknown. Combining these aspects we conclude that connectomes are constitutively epistemic objects: there just is no way to turn them into permanent and complete technical standards because the possibilities to map connection properties under different modeling assumptions are potentially inexhaustible. In the second part of the chapter, we use this understanding of connectomes as constitutively epistemic objects in order to critically assess the historical and political dimensions of current neuroscientific research. We argue that connectomics shows how the notion of the "brain as a network" has become the dominant metaphor of contemporary brain research. We further point out that this metaphor shares (potentially problematic) affinities to the form of contemporary "network societies." We close by pointing out how the relation between connectomes and networks in society could be used in a more fruitful manner. © 2017 Elsevier B.V. All rights reserved.

Brief: Multizone subsea completions in the Dai Hung field, Vietnam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lay, K.R.

1996-04-01

The early production phase of the Dai Hung field development involved drilling and completion of five subsea wells. Owing to the complex nature of the reservoirs, selective multizone completions were installed for effective reservoir data acquisition and reservoir management. Downhole completion designs used equipment that was primarily of existing proven design, and downhole equipment was installed in a single trip. Ongoing reservoir management will be aided by use of a subsea wireline system to facilitate data acquisition.

Performance predictions affect attentional processes of event-based prospective memory.

PubMed

Rummel, Jan; Kuhlmann, Beatrice G; Touron, Dayna R

2013-09-01

To investigate whether making performance predictions affects prospective memory (PM) processing, we asked one group of participants to predict their performance in a PM task embedded in an ongoing task and compared their performance with a control group that made no predictions. A third group gave not only PM predictions but also ongoing-task predictions. Exclusive PM predictions resulted in slower ongoing-task responding both in a nonfocal (Experiment 1) and in a focal (Experiment 2) PM task. Only in the nonfocal task was the additional slowing accompanied by improved PM performance. Even in the nonfocal task, however, was the correlation between ongoing-task speed and PM performance reduced after predictions, suggesting that the slowing was not completely functional for PM. Prediction-induced changes could be avoided by asking participants to additionally predict their performance in the ongoing task. In sum, the present findings substantiate a role of metamemory for attention-allocation strategies of PM. Copyright © 2013 Elsevier Inc. All rights reserved.

Satellite Communications Using Commercial Protocols

NASA Technical Reports Server (NTRS)

Ivancic, William D.; Griner, James H.; Dimond, Robert; Frantz, Brian D.; Kachmar, Brian; Shell, Dan

2000-01-01

NASA Glenn Research Center has been working with industry, academia, and other government agencies in assessing commercial communications protocols for satellite and space-based applications. In addition, NASA Glenn has been developing and advocating new satellite-friendly modifications to existing communications protocol standards. This paper summarizes recent research into the applicability of various commercial standard protocols for use over satellite and space- based communications networks as well as expectations for future protocol development. It serves as a reference point from which the detailed work can be readily accessed. Areas that will be addressed include asynchronous-transfer-mode quality of service; completed and ongoing work of the Internet Engineering Task Force; data-link-layer protocol development for unidirectional link routing; and protocols for aeronautical applications, including mobile Internet protocol routing for wireless/mobile hosts and the aeronautical telecommunications network protocol.

Ongoing training of community health workers in low-income and middle-income countries: a systematic scoping review of the literature

PubMed Central

O’Donovan, Charles; Kuhn, Isla; Sachs, Sonia Ehrlich

2018-01-01

Objectives Understanding the current landscape of ongoing training for community health workers (CHWs) in low-income and middle-income countries (LMICs) is important both for organisations responsible for their training, as well as researchers and policy makers. This scoping review explores this under-researched area by mapping the current delivery implementation and evaluation of ongoing training provision for CHWs in LMICs. Design Systematic scoping review. Data sources MEDLINE, Embase, AMED, Global Health, Web of Science, Scopus, ASSIA, LILACS, BEI and ERIC. Study selection Original studies focusing on the provision of ongoing training for CHWs working in a country defined as low income and middle income according to World Bank Group 2012 classification of economies. Results The scoping review found 35 original studies that met the inclusion criteria. Ongoing training activities for CHWs were described as supervision (n=19), inservice or refresher training (n=13) or a mixture of both (n=3). Although the majority of studies emphasised the importance of providing ongoing training, several studies reported no impact of ongoing training on performance indicators. The majority of ongoing training was delivered inperson; however, four studies reported the use of mobile technologies to support training delivery. The outcomes from ongoing training activities were measured and reported in different ways, including changes in behaviour, attitudes and practice measured in a quantitative manner (n=16), knowledge and skills (n=6), qualitative assessments (n=5) or a mixed methods approach combining one of the aforementioned modalities (n=8). Conclusions This scoping review highlights the diverse range of ongoing training for CHWs in LMICs. Given the expansion of CHW programmes globally, more attention should be given to the design, delivery, monitoring and sustainability of ongoing training from a health systems strengthening perspective. PMID:29705769

Evaluating Fluorscence-Based Metrics for Early Detection of ...

EPA Pesticide Factsheets

Summary: This paper discusses the results of an ongoing Water Research Foundation project on developing a fluorescence sensor system for early detection of distribution system nitrification Summary: This paper discusses the results of an ongoing Water Research Foundation project on developing a fluorescence sensor system for early detection of distribution system nitrification

40 CFR Appendix W to Part 51 - Guideline on Air Quality Models

Code of Federal Regulations, 2013 CFR

2013-07-01

... in the Guideline. The third activity is the extensive on-going research efforts by EPA and others in... addition, findings from ongoing research programs, new model development, or results from model evaluations... shown that the model is not biased toward underestimates; and v. A protocol on methods and procedures to...

40 CFR Appendix W to Part 51 - Guideline on Air Quality Models

Code of Federal Regulations, 2012 CFR

2012-07-01

... in the Guideline. The third activity is the extensive on-going research efforts by EPA and others in... addition, findings from ongoing research programs, new model development, or results from model evaluations... shown that the model is not biased toward underestimates; and v. A protocol on methods and procedures to...

40 CFR Appendix W to Part 51 - Guideline on Air Quality Models

Code of Federal Regulations, 2014 CFR

2014-07-01

... in the Guideline. The third activity is the extensive on-going research efforts by EPA and others in... addition, findings from ongoing research programs, new model development, or results from model evaluations... shown that the model is not biased toward underestimates; and v. A protocol on methods and procedures to...

Bioelectromagnetics Research within an Australian Context: The Australian Centre for Electromagnetic Bioeffects Research (ACEBR).

PubMed

Loughran, Sarah P; Al Hossain, Md Shahriar; Bentvelzen, Alan; Elwood, Mark; Finnie, John; Horvat, Joseph; Iskra, Steve; Ivanova, Elena P; Manavis, Jim; Mudiyanselage, Chathuranga Keerawella; Lajevardipour, Alireza; Martinac, Boris; McIntosh, Robert; McKenzie, Raymond; Mustapic, Mislav; Nakayama, Yoshitaka; Pirogova, Elena; Rashid, M Harunur; Taylor, Nigel A; Todorova, Nevena; Wiedemann, Peter M; Vink, Robert; Wood, Andrew; Yarovsky, Irene; Croft, Rodney J

2016-09-29

Mobile phone subscriptions continue to increase across the world, with the electromagnetic fields (EMF) emitted by these devices, as well as by related technologies such as Wi-Fi and smart meters, now ubiquitous. This increase in use and consequent exposure to mobile communication (MC)-related EMF has led to concern about possible health effects that could arise from this exposure. Although much research has been conducted since the introduction of these technologies, uncertainty about the impact on health remains. The Australian Centre for Electromagnetic Bioeffects Research (ACEBR) is a National Health and Medical Research Council Centre of Research Excellence that is undertaking research addressing the most important aspects of the MC-EMF health debate, with a strong focus on mechanisms, neurodegenerative diseases, cancer, and exposure dosimetry. This research takes as its starting point the current scientific status quo, but also addresses the adequacy of the evidence for the status quo. Risk communication research complements the above, and aims to ensure that whatever is found, it is communicated effectively and appropriately. This paper provides a summary of this ACEBR research (both completed and ongoing), and discusses the rationale for conducting it in light of the prevailing science.

Conducting qualitative research within Clinical Trials Units: avoiding potential pitfalls.

PubMed

Cooper, Cindy; O'Cathain, Alicia; Hind, Danny; Adamson, Joy; Lawton, Julia; Baird, Wendy

2014-07-01

The value of using qualitative research within or alongside randomised controlled trials (RCTs) is becoming more widely accepted. Qualitative research may be conducted concurrently with pilot or full RCTs to understand the feasibility and acceptability of the interventions being tested, or to improve trial conduct. Clinical Trials Units (CTUs) in the United Kingdom (UK) manage large numbers of RCTs and, increasingly, manage the qualitative research or collaborate with qualitative researchers external to the CTU. CTUs are beginning to explicitly manage the process, for example, through the use of standard operating procedures for designing and implementing qualitative research with trials. We reviewed the experiences of two UK Clinical Research Collaboration (UKCRC) registered CTUs of conducting qualitative research concurrently with RCTs. Drawing on experiences gained from 15 studies, we identify the potential for the qualitative research to undermine the successful completion or scientific integrity of RCTs. We show that potential problems can arise from feedback of interim or final qualitative findings to members of the trial team or beyond, in particular reporting qualitative findings whilst the trial is on-going. The problems include: We make recommendations for improving the management of qualitative research within CTUs. Copyright © 2014. Published by Elsevier Inc.

Bioelectromagnetics Research within an Australian Context: The Australian Centre for Electromagnetic Bioeffects Research (ACEBR)

PubMed Central

Loughran, Sarah P.; Al Hossain, Md Shahriar; Bentvelzen, Alan; Elwood, Mark; Finnie, John; Horvat, Joseph; Iskra, Steve; Ivanova, Elena P.; Manavis, Jim; Mudiyanselage, Chathuranga Keerawella; Lajevardipour, Alireza; Martinac, Boris; McIntosh, Robert; McKenzie, Raymond; Mustapic, Mislav; Nakayama, Yoshitaka; Pirogova, Elena; Rashid, M. Harunur; Taylor, Nigel A.; Todorova, Nevena; Wiedemann, Peter M.; Vink, Robert; Wood, Andrew; Yarovsky, Irene; Croft, Rodney J.

2016-01-01

Mobile phone subscriptions continue to increase across the world, with the electromagnetic fields (EMF) emitted by these devices, as well as by related technologies such as Wi-Fi and smart meters, now ubiquitous. This increase in use and consequent exposure to mobile communication (MC)-related EMF has led to concern about possible health effects that could arise from this exposure. Although much research has been conducted since the introduction of these technologies, uncertainty about the impact on health remains. The Australian Centre for Electromagnetic Bioeffects Research (ACEBR) is a National Health and Medical Research Council Centre of Research Excellence that is undertaking research addressing the most important aspects of the MC-EMF health debate, with a strong focus on mechanisms, neurodegenerative diseases, cancer, and exposure dosimetry. This research takes as its starting point the current scientific status quo, but also addresses the adequacy of the evidence for the status quo. Risk communication research complements the above, and aims to ensure that whatever is found, it is communicated effectively and appropriately. This paper provides a summary of this ACEBR research (both completed and ongoing), and discusses the rationale for conducting it in light of the prevailing science. PMID:27690076

Treating Gulf War Illness with Novel Anti-Inflammatories: A Screening of Botantical Microglia Modulators

DTIC Science & Technology

2016-10-01

approval and initiated advertising , recruitment, participant screening, participant enrollment, and the study protocol. All start up subtasks have been...be made to enroll these during the next reporting period. Advertisement , recruitment, screening, and enrollment are ongoing as we work toward the...Regulatory Approvals 100% Completed. • Task 3: Start up 100% Completed. Milestone: Protocol ready to begin—Completed • Task 4: Advertisement 40

The impact of cognitive control on children's goal monitoring in a time-based prospective memory task.

PubMed

Mahy, Caitlin E V; Voigt, Babett; Ballhausen, Nicola; Schnitzspahn, Katharina; Ellis, Judi; Kliegel, Matthias

2015-01-01

The present study investigated whether developmental changes in cognitive control may underlie improvements of time-based prospective memory. Five-, 7-, 9-, and 11-year-olds (N = 166) completed a driving simulation task (ongoing task) in which they had to refuel their vehicle at specific points in time (PM task). The availability of cognitive control resources was experimentally manipulated by imposing a secondary task that required divided attention. Children completed the driving simulation task both in a full-attention condition and a divided-attention condition where they had to carry out a secondary task. Results revealed that older children performed better than younger children on the ongoing task and PM task. Children performed worse on the ongoing and PM tasks in the divided-attention condition compared to the full-attention condition. With respect to time monitoring in the final interval prior to the PM target, divided attention interacted with age such that older children's time monitoring was more negatively affected by the secondary task compared to younger children. Results are discussed in terms of developmental shifts from reactive to proactive monitoring strategies.

A comparison of transfer-appropriate processing and multi-process frameworks for prospective memory performance.

PubMed

McBride, Dawn M; Abney, Drew H

2012-01-01

We examined multi-process (MP) and transfer-appropriate processing descriptions of prospective memory (PM). Three conditions were compared that varied the overlap in processing type (perceptual/conceptual) between the ongoing and PM tasks such that two conditions involved a match of perceptual processing and one condition involved a mismatch in processing (conceptual ongoing task/perceptual PM task). One of the matched processing conditions also created a focal PM task, whereas the other two conditions were considered non-focal (Einstein & McDaniel, 2005). PM task accuracy and ongoing task completion speed in baseline and PM task conditions were measured. Accuracy results indicated a higher PM task completion rate for the focal condition than the non-focal conditions, a finding that is consistent with predictions made by the MP view. However, reaction time (RT) analyses indicated that PM task cost did not differ across conditions when practice effects are considered. Thus, the PM accuracy results are consistent with a MP description of PM, but RT results did not support the MP view predictions regarding PM cost.

Prospective memory in context: Moving through a familiar space.

PubMed

Smith, Rebekah E; Hunt, R Reed; Murray, Amy E

2017-02-01

Successful completion of delayed intentions is a common but important aspect of daily behavior. Such behavior requires not only memory for the intended action but also recognition of the opportunity to perform that action, known collectively as prospective memory. The fact that prospective memory tasks occur in the midst of other activities is captured in laboratory tasks by embedding the prospective memory task in an ongoing activity. In many cases the requirement to perform the prospective memory task results in a reduction in ongoing performance relative to when the ongoing task is performed alone. This is referred to as the cost to the ongoing task and reflects the allocation of attentional resources to the prospective memory task. The current study examined the pattern of cost across the ongoing task when the ongoing task provided contextual information that in turn allowed participants to anticipate when target events would occur within the ongoing task. The availability of contextual information reduced ongoing task response times overall, with an increase in response times closer to the target locations (Experiments 1-3). The fourth study, drawing on the Event Segmentation Theory, provided support for the proposal made by the Preparatory Attentional and Memory Processes theory of prospective memory that decisions about the allocation of attention to the prospective memory task are more likely to be made at points of transition. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Missing the target: including perspectives of women with overweight and obesity to inform stigma‐reduction strategies

PubMed Central

Himmelstein, M. S.; Gorin, A. A.; Suh, Y. J.

2017-01-01

Summary Objective Pervasive weight stigma and discrimination have led to ongoing calls for efforts to reduce this bias. Despite increasing research on stigma‐reduction strategies, perspectives of individuals who have experienced weight stigma have rarely been included to inform this research. The present study conducted a systematic examination of women with high body weight to assess their perspectives about a broad range of strategies to reduce weight‐based stigma. Methods Women with overweight or obesity (N = 461) completed an online survey in which they evaluated the importance, feasibility and potential impact of 35 stigma‐reduction strategies in diverse settings. Participants (91.5% who reported experiencing weight stigma) also completed self‐report measures assessing experienced and internalized weight stigma. Results Most participants assigned high importance to all stigma‐reduction strategies, with school‐based and healthcare approaches accruing the highest ratings. Adding weight stigma to existing anti‐harassment workplace training was rated as the most impactful and feasible strategy. The family environment was viewed as an important intervention target, regardless of participants' experienced or internalized stigma. Conclusion These findings underscore the importance of including people with stigmatized identities in stigma‐reduction research; their insights provide a necessary and valuable contribution that can inform ways to reduce weight‐based inequities and prioritize such efforts. PMID:28392929

Multizone subsea completions in the Dai Hung field, Vietnam

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lay, K.R.

1996-09-01

The early production phase of the Dai Hung field development resulted in the drilling and completion of five subsea wells. Because of the complex nature of the reservoirs, selective multizone completions were installed for effective reservoir data acquisition and reservoir management. The downhole completion designs used equipment that was primarily of existing proven design and downhole equipment installation was successfully achieved in a single trip. Ongoing reservoir management will be aided by the use of a subsea wireline system to facilitate data acquisition.

SOARS: Significant Opportunities in Atmospheric Research and Science

NASA Astrophysics Data System (ADS)

Windham, T. L.; Hagan, M. E.

2001-05-01

SOARS, a model program, has developed a unique mutli-year mentoring and learning community to support, teach, and guide college students from diverse backgrounds. SOARS is dedicated to increasing the number of African American, American Indian, and Hispanic/Latino students enrolled in master's and doctoral degree programs in the atmospheric and related sciences with the goal of supporting the development of a diverse, internationally competitive and globally engaged workforce within the scientific community. Since its 1996 inception, 51 undergraduates have participated. All 51 completed or are on schedule to complete their undergraduate degrees with a major in an atmospheric or related science. Currently 17 protégés are in graduate programs. Eight have completed M.S. degrees; two are Ph.D. candidates. SOARS has a retention rate of 82 percent. The SOARS learning community provides multi-year programing for protégés that includes educational and research opportunities, mentoring, career counseling and guidance, and the possibility of financial support for a graduate level program. Protégés spend their summers at NCAR, participate in ongoing research projects, an eight week scientific writing and communication workshop, and scientific seminars. They benefit from long-term mentoring from respected scientists and professionals, learn about career opportunities, practice leadership and are encouraged to complete a graduate program in an atmospheric or related science. In this presentation we highlight the SOARS program structure and objectives with particular emphasis on the mentoring model that is fundamental to SOARS. We conclude with a summary of SOARS protégés' contributions to the broader scientific community which include oral and poster presentations at national and regional scientific conferences, as well as co-authorship of refereed journal articles.

The U.S. Forest Service's analysis of cumulative effects to wildlife: A study of legal standards, current practice, and ongoing challenges on a National Forest

DOE Office of Scientific and Technical Information (OSTI.GOV)

Schultz, Courtney A., E-mail: courtney.schultz@colostate.edu

Cumulative effects analysis (CEA) allows natural resource managers to understand the status of resources in historical context, learn from past management actions, and adapt future activities accordingly. U.S. federal agencies are required to complete CEA as part of environmental impact assessment under the National Environmental Policy Act (NEPA). Past research on CEA as part of NEPA has identified significant deficiencies in CEA practice, suggested methodologies for handling difficult aspects of CEA, and analyzed the rise in litigation over CEA in U.S. courts. This article provides a review of the literature and legal standards related to CEA as it is donemore » under NEPA and then examines current practice on a U.S. National Forest, utilizing qualitative methods in order to provide a detailed understanding of current approaches to CEA. Research objectives were to understand current practice, investigate ongoing challenges, and identify impediments to improvement. Methods included a systematic review of a set of NEPA documents and semi-structured interviews with practitioners, scientists, and members of the public. Findings indicate that the primary challenges associated with CEA include: issues of both geographic and temporal scale of analysis, confusion over the purpose of the requirement, the lack of monitoring data, and problems coordinating and disseminating data. Improved monitoring strategies and programmatic analyses could support improved CEA practice.« less

Invited review: Experimental design, data reporting, and sharing in support of animal systems modeling research.

PubMed

McNamara, J P; Hanigan, M D; White, R R

2016-12-01

The National Animal Nutrition Program "National Research Support Project 9" supports efforts in livestock nutrition, including the National Research Council's committees on the nutrient requirements of animals. Our objective was to review the status of experimentation and data reporting in animal nutrition literature and to provide suggestions for the advancement of animal nutrition research and the ongoing improvement of field-applied nutrient requirement models. Improved data reporting consistency and completeness represent a substantial opportunity to improve nutrition-related mathematical models. We reviewed a body of nutrition research; recorded common phrases used to describe diets, animals, housing, and environmental conditions; and proposed equivalent numerical data that could be reported. With the increasing availability of online supplementary material sections in journals, we developed a comprehensive checklist of data that should be included in publications. To continue to improve our research effectiveness, studies utilizing multiple research methodologies to address complex systems and measure multiple variables will be necessary. From the current body of animal nutrition literature, we identified a series of opportunities to integrate research focuses (nutrition, reproduction and genetics) to advance the development of nutrient requirement models. From our survey of current experimentation and data reporting in animal nutrition, we identified 4 key opportunities to advance animal nutrition knowledge: (1) coordinated experiments should be designed to employ multiple research methodologies; (2) systems-oriented research approaches should be encouraged and supported; (3) publication guidelines should be updated to encourage and support sharing of more complete data sets; and (4) new experiments should be more rapidly integrated into our knowledge bases, research programs and practical applications. Copyright © 2016 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

Overview of the OGAP Formative Assessment Project and CPRE's Large-Scale Experimental Study of Implementation and Impacts

ERIC Educational Resources Information Center

Supovitz, Jonathan

2016-01-01

In this presentation discussed in this brief abstracted report, the author presents about an ongoing partnership with the Philadelphia School District (PSD) to implement and research the Ongoing Assessment Project (OGAP). OGAP is a systematic, intentional and iterative formative assessment system grounded in the research on how students learn…

Ongoing clinical trials of PD-1 and PD-L1 inhibitors for lung cancer in China.

PubMed

Liu, Si-Yang; Wu, Yi-Long

2017-07-05

Compared to chemotherapy, promising results have been obtained by blocking the PD-1 pathway using antibodies that inhibit programmed cell death protein 1 (PD-1) or programmed cell death protein ligand 1 (PD-L1). Furthermore, global researchers and doctors are exploring how to optimize this immunotherapy in 270 clinical studies. However, Chinese clinical trials of these agents remain in the early stages. We summarize the ongoing international and domestic clinical trials using PD-1 and PD-L1 inhibitors to treat lung cancer. This information can help researchers better understand the active and approved clinical trials in China, as well as the ongoing research regarding PD-1 and PD-L1 inhibitors.

Composites for Advanced Space Transportation Systems (CASTS)

NASA Technical Reports Server (NTRS)

Davis, J. G., Jr. (Compiler)

1979-01-01

A summary is given of the in-house and contract work accomplished under the CASTS Project. In July 1975 the CASTS Project was initiated to develop graphite fiber/polyimide matrix (GR/PI) composite structures with 589K (600 F) operational capability for application to aerospace vehicles. Major tasks include: (1) screening composites and adhesives, (2) developing fabrication procedures and specifications, (3) developing design allowables test methods and data, and (4) design and test of structural elements and construction of an aft body flap for the Space Shuttle Orbiter Vehicle which will be ground tested. Portions of the information are from ongoing research and must be considered preliminary. The CASTS Project is scheduled to be completed in September 1983.

Are we prepared to help low-resource communities cope with a severe influenza pandemic?

PubMed

Starbuck, Eric S; von Bernuth, Rudolph; Bolles, Kathryn; Koepsell, Jeanne

2013-11-01

Recent research involving lab-modified H5N1 influenza viruses with increased transmissibility and the ongoing evolution of the virus in nature should remind us of the continuing importance of preparedness for a severe influenza pandemic. Current vaccine technology and antiviral supply remain inadequate, and in a severe pandemic, most low-resource communities will fail to receive adequate medical supplies. However, with suitable guidance, these communities can take appropriate actions without substantial outside resources to reduce influenza transmission and care for the ill. Such guidance should be completed, and support provided to developing countries to adapt it for their settings and prepare for implementation. © 2012 John Wiley & Sons Ltd.

Antibodies and antimatter: the resurgence of immuno-PET.

PubMed

Wu, Anna M

2009-01-01

The completion of the human genome, coupled with parallel major research efforts in proteomics and systems biology, has led to a flood of information on the roles of individual genes and proteins in normal physiologic processes and their disruptions in disease. In practical terms, this information has opened the door to increasingly targeted therapies as specific molecular markers are identified and validated. The ongoing transition from empiric to molecular medicine has engendered a need for corresponding molecular diagnostics, including noninvasive molecular imaging. Convergence of knowledge regarding key biomarkers that define normal biologic processes and disease with protein and imaging technology makes this an opportune time to revisit the combination of antibodies and PET, or immuno-PET.

Annotating MYC Status in Treatment-Resistant Metastatic Castration-Resistant Prostate Cancer With Gallium-68 Citrate PET

DTIC Science & Technology

2017-09-01

ongoing and interim analysis is planned within the next 6 months. Planned analyses include: 1) correlation of gallium citrate uptake on PET with MYC...utility of Gallium citrate PET as a pharmacodynamic and predictive biomarker of MYC pathway inhibition in mCRPC. Correlative pre- and post-treatment...completed Milestone Achieved: Last patient completes study follow up scan 36 Not yet completed Assess correlation between SUVmax on gallium

F Reactor Inspection

ScienceCinema

Grindstaff, Keith; Hathaway, Boyd; Wilson, Mike

2018-01-16

Workers from Mission Support Alliance, LLC., removed the welds around the steel door of the F Reactor before stepping inside the reactor to complete its periodic inspection. This is the first time the Department of Energy (DOE) has had the reactor open since 2008. The F Reactor is one of nine reactors along the Columbia River at the Department's Hanford Site in southeastern Washington State, where environmental cleanup has been ongoing since 1989. As part of the Tri-Party Agreement, the Department completes surveillance and maintenance activities of cocooned reactors periodically to evaluate the structural integrity of the safe storage enclosure and to ensure confinement of any remaining hazardous materials. "This entry marks a transition of sorts because the Hanford Long-Term Stewardship Program, for the first time, was responsible for conducting the entry and surveillance and maintenance activities," said Keith Grindstaff, Energy Department Long-Term Stewardship Program Manager. "As the River Corridor cleanup work is completed and transitioned to long-term stewardship, our program will manage any on-going requirements."

F Reactor Inspection

DOE Office of Scientific and Technical Information (OSTI.GOV)

Grindstaff, Keith; Hathaway, Boyd; Wilson, Mike

2014-10-29

Workers from Mission Support Alliance, LLC., removed the welds around the steel door of the F Reactor before stepping inside the reactor to complete its periodic inspection. This is the first time the Department of Energy (DOE) has had the reactor open since 2008. The F Reactor is one of nine reactors along the Columbia River at the Department's Hanford Site in southeastern Washington State, where environmental cleanup has been ongoing since 1989. As part of the Tri-Party Agreement, the Department completes surveillance and maintenance activities of cocooned reactors periodically to evaluate the structural integrity of the safe storage enclosuremore » and to ensure confinement of any remaining hazardous materials. "This entry marks a transition of sorts because the Hanford Long-Term Stewardship Program, for the first time, was responsible for conducting the entry and surveillance and maintenance activities," said Keith Grindstaff, Energy Department Long-Term Stewardship Program Manager. "As the River Corridor cleanup work is completed and transitioned to long-term stewardship, our program will manage any on-going requirements."« less

Growing our own: building a native research team.

PubMed

Gray, Jacqueline S; Carter, Paula M

2012-01-01

In 2006, American Indian/Alaska Natives (AI/AN) made up less than 1% of the science, engineering and health doctorates in the U.S. Early introduction of AI/AN students to research and continued opportunities are necessary to develop successful AI/AN researchers who can better serve their communities. This team was developed to form a cohort of American Indian students, staff and faculty interested in research and becoming researchers. Since implementation, the program grew from one student to over 20 AI students ranging from freshmen just entering college to doctoral students working to complete their dissertations. This article highlights the team growth, increasing structure, student needs and the faculty and staff involved. It further addresses the support and educational aspects of growing an ongoing, multidisciplinary research team committed to ethical research in Native communities. The team addresses substance use prevalence, the relationship of substance abuse to other mental health diagnoses, and treatment issues. The team includes weekly team meetings, a Blackboard site on the Internet that is populated with resources and focused on sharing materials and information, a weekly journal club discussion of research articles, and collaborative discussions on each project and the barriers and challenges that need to be addressed to move forward.

The Failure of Deactivating Intentions: Aftereffects of Completed Intentions in the Repeated Prospective Memory Cue Paradigm

ERIC Educational Resources Information Center

Walser, Moritz; Fischer, Rico; Goschke, Thomas

2012-01-01

We used a newly developed experimental paradigm to investigate aftereffects of completed intentions on subsequent performance that required the maintenance and execution of new intentions. Participants performed an ongoing number categorization task and an additional prospective memory (PM) task, which required them to respond to PM cues that…

Engaging, Recruiting, and Retaining Black Men Who Have Sex With Men in Research Studies: Don’t Underestimate the Importance of Staffing—Lessons Learned From HPTN 061, the BROTHERS Study

PubMed Central

Magnus, Manya; Franks, Julie; Griffith, Sam; Arnold, Michael P.; Goodman, Krista; Wheeler, Darrell P.

2014-01-01

Context HIV/AIDS in the United States continues to primarily impact men who have sex with men (MSM), with disproportionately high rates among black MSM. Objective The purpose of this study was to identify factors that may influence engagement and retention of black MSM in HIV research. Design and Participants This was a qualitative evaluation of study implementation within a multisite, prospective, observational study (HIV Prevention Trials Network 061, BROTHERS) that enrolled 1553 black MSM in 6 cities throughout the United States. Data collection for this evaluation included a written, structured survey collected from each of the sites describing site characteristics including staff and organizational structure, reviews of site standard operating procedures, and work plans; semistructured key informant interviews were conducted with site coordinators to characterize staffing, site-level factors facilitating or impeding effective community engagement, study recruitment, and retention. Data from completed surveys and site standard operating procedures were collated, and notes from key informant interviews were thematically coded for content by 2 independent reviewers. Results Several key themes emerged from the data, including the importance of inclusion of members of the community being studied as staff, institutional hiring practices that support inclusive staffing, cultivating a supportive working environment for study implementation, and ongoing relationships between research institutions and community. Conclusions This study underscores the importance of staffing in implementing research with black MSM. Investigators should consider how staffing and organizational structures affect implementation during study design and when preparing to initiate study activities. Ongoing monitoring of community engagement can inform and improve methods for engagement and ensure cultural relevance while removing barriers for participation. PMID:24406940

Engaging, recruiting, and retaining black men who have sex with men in research studies: don't underestimate the importance of staffing--lessons learned from HPTN 061, the BROTHERS study.

PubMed

Magnus, Manya; Franks, Julie; Griffith, Sam; Arnold, Michael P; Goodman, Krista; Wheeler, Darrell P

2014-01-01

HIV/AIDS in the United States continues to primarily impact men who have sex with men (MSM), with disproportionately high rates among black MSM. The purpose of this study was to identify factors that may influence engagement and retention of black MSM in HIV research. This was a qualitative evaluation of study implementation within a multisite, prospective, observational study (HIV Prevention Trials Network 061, BROTHERS) that enrolled 1553 black MSM in 6 cities throughout the United States. Data collection for this evaluation included a written, structured survey collected from each of the sites describing site characteristics including staff and organizational structure, reviews of site standard operating procedures, and work plans; semistructured key informant interviews were conducted with site coordinators to characterize staffing, site-level factors facilitating or impeding effective community engagement, study recruitment, and retention. Data from completed surveys and site standard operating procedures were collated, and notes from key informant interviews were thematically coded for content by 2 independent reviewers. Several key themes emerged from the data, including the importance of inclusion of members of the community being studied as staff, institutional hiring practices that support inclusive staffing, cultivating a supportive working environment for study implementation, and ongoing relationships between research institutions and community. This study underscores the importance of staffing in implementing research with black MSM. Investigators should consider how staffing and organizational structures affect implementation during study design and when preparing to initiate study activities. Ongoing monitoring of community engagement can inform and improve methods for engagement and ensure cultural relevance while removing barriers for participation.

Clinical Trials | Division of Cancer Prevention

Cancer.gov

Information about actively enrolling, ongoing, and completed clinical trials of cancer prevention, early detection, and supportive care, including phase I, II, and III agent and action trials and clinical trials management. |

Assessment of the U.S. Department of Defense Efforts to Develop an Effective Medical Logistics System within the Afghan National Security Forces

DTIC Science & Technology

2011-06-14

aggressively to strengthen measures aimed at ensuring a successful ANSF transition. Ongoing actions include: • Working with CURE International and the ANSF...sustainability include the following ongoing actions: • Working with CURE International and the MoD and MoI to complete, promulgate and implement Standards of Care...approximately June-August 2011. In addition, NTM-A/CSTC-A previously awarded an approximately $1.57M contract with the NGO CURE International to

Teaching the Teachers: Physical Science for the Non-Scientific

NASA Astrophysics Data System (ADS)

Michels, D. J.; Pickert, S. M.; Montrose, C. J.; Thompson, J. L.

2004-12-01

The Catholic University of America, in collaboration with the Solar Physics Branch of the Naval Research Laboratory and the Goddard Space Flight Center, has begun development of an experimental, inquiry-driven and standards-referenced physical science course for undergraduate, pre-service K-8 teachers. The course is team-taught by faculty from the University's Departments of Education and Physics and NRL solar physics research personnel. Basic physical science concepts are taught in the context of the Sun and Sun-Earth Connections, through direct observation, web-based solar data, and images and movies from ongoing space missions. The Sun can illuminate, in ways that cannot be duplicated with comparable clarity in the laboratory, the basics of magnetic and gravitational force fields, Newton's Laws, and light and optics. The immediacy of the connection to ongoing space research and live mission data serves as well to inspire student interest and curiosity. Teaching objectives include pedagogical methods, especially hands-on and observational experiences appropriate to the physics content and the K-8 classroom. The CUA Program, called TOPS! (Top Teachers of Physical Science!) has completed its first year of classroom experience; the first few batches of Program graduates should be in K-8 classrooms in time to capitalize on the motivational opportunities offered by the 2007-2008 IHY and IPY. We present data on the attitudinal and scientific progress of fifteen pre-service Early Childhood and Elementary Education majors as they experienced, many for the first time, the marvels of attractive and repulsive forces, live observations of solar system dynamics, access to real-time satellite data and NASA educational resources.

Prospective memory in young and older adults: the effects of task importance and ongoing task load.

PubMed

Smith, Rebekah E; Hunt, R Reed

2014-01-01

Remembering to perform an action in the future, called prospective memory, often shows age-related differences in favor of young adults when tested in the laboratory. Recently Smith, Horn, and Bayen (2012; Aging, Neuropsychology, and Cognition, 19, 495) embedded a PM task in an ongoing color-matching task and manipulated the difficulty of the ongoing task by varying the number of colors on each trial of the task. Smith et al. found that age-related differences in PM performance (lower PM performance for older adults relative to young adults) persisted even when older adults could perform the ongoing task as well or better than the young adults. The current study investigates a possible explanation for the pattern of results reported by Smith et al. by including a manipulation of task emphasis: for half of the participants the prospective memory task was emphasize, while for the other half the ongoing color-matching task was emphasized. Older adults performed a 4-color version of the ongoing color-matching task, while young adults completed either the 4-color or a more difficult 6-color version of the ongoing task. Older adults failed to perform as well as the young adults on the prospective memory task regardless of task emphasis, even when older adults were performing as well or better than the young adults on the ongoing color-matching task. The current results indicate that the lack of an effect of ongoing task load on prospective memory task performance is not due to a perception that one or the other task is more important than the other.

Stress Controlled Catalysis via Engineered Nanostructures

DTIC Science & Technology

2016-03-02

Brown University and California State University –Northridge: Shouheng Sun, Andrew Peterson, Sharvan Kumar , Gang Lu and William Curtin. In addition...Peterson, Sharvan Kumar , Gang Lu and William Curtin. In addition, the workshop leveraged the opportunities of reviewing past and ongoing research on...Peterson, Sharvan Kumar , Gang Lu and William Curtin. In addition, the workshop leveraged the opportunities of reviewing past and ongoing research

The MOOC and Learning Analytics Innovation Cycle (MOLAC): A Reflective Summary of Ongoing Research and Its Challenges

ERIC Educational Resources Information Center

Drachsler, H.; Kalz, M.

2016-01-01

The article deals with the interplay between learning analytics and massive open online courses (MOOCs) and provides a conceptual framework to situate ongoing research in the MOOC and learning analytics innovation cycle (MOLAC framework). The MOLAC framework is organized on three levels: On the micro-level, the data collection and analytics…

Report on Partial Findings of an Ongoing Research: Social Networking Sites (SNS) as a Platform to Support Teaching and Learning in Secondary Schools

ERIC Educational Resources Information Center

Bt. Ubaidullah, Nor Hasbiah; Samsuddin, Khairulanuar; Bt. Fabil, Norsikin; Bt. Mahadi, Norhayati

2011-01-01

This paper reports the partial findings of a survey that was carried out in the analysis phase of an ongoing research for the development of a prototype of a Social Networking Site (SNS) to support teaching and learning in secondary schools. For the initial phase of the study, a quantitative research method was used based on a survey involving 383…

Professor in Residence: An Innovative Academic-Practice Partnership.

PubMed

Hinic, Katherine; Kowalski, Mildred Ortu; Silverstein, Wendy

2017-12-01

This article describes an academic-practice partnership between an American Nurses Credentialing Center Magnet ® -designated hospital and an academic nurse educator that has increased the hospital's capacity for research, evidence-based practice, and support for nurses continuing their education. Through close collaboration with the full-time nurse researcher and members of the nursing education department, the professor in residence consults with clinical staff to support completion of research and evidence-based practice projects. The collaboration also has resulted in the development of a formal year-long mentoring program for clinical nurses in the area of evidence-based practice. Individual support and academic consults are offered to nurses enrolled in school to promote advancement of nurses' educational level. This collaboration has been beneficial for both the hospital and the university, increasing the capacity for scholarly activities for nurses in the hospital and serving as a forum for ongoing faculty practice and scholarship. J Contin Educ Nurs. 2017;48(12):552-556. Copyright 2017, SLACK Incorporated.

Research Ethics Education in the STEM Disciplines: The Promises and Challenges of a Gaming Approach.

PubMed

Briggle, Adam; Holbrook, J Britt; Oppong, Joseph; Hoffmann, Joesph; Larsen, Elizabeth K; Pluscht, Patrick

2016-02-01

While education in ethics and the responsible conduct of research (RCR) is widely acknowledged as an essential component of graduate education, particularly in the STEM disciplines (science, technology, engineering, and math), little consensus exists on how best to accomplish this goal. Recent years have witnessed a turn toward the use of games in this context. Drawing from two NSF-funded grants (one completed and one on-going), this paper takes a critical look at the use of games in ethics and RCR education. It does so by: (a) setting the development of research and engineering ethics games in wider historical and theoretical contexts, which highlights their promise to solve important pedagogical problems; (b) reporting on some initial results from our own efforts to develop a game; and (c) reflecting on the challenges that arise in using games for ethics education. In our discussion of the challenges, we draw out lessons to improve this nascent approach to ethics education in the STEM disciplines .

Relationship between cancer-related traumatic stress and family milestone achievement in adolescent and young adult survivors of childhood cancer.

PubMed

Tillery, Rachel; Beal, Sarah J; Thompson, Aimee N; Pai, Ahna L H

2018-06-01

Late physical and emotional effects of cancer treatment pose a burden for adolescent and young adult survivors of childhood cancer, including family milestone achievement. This brief report examined links between ongoing cancer-related post-traumatic stress symptoms (CR-PTSS) and family milestone achievement. Survivors (n = 51; M age  = 24.73, SD = 8.20) completed CR-PTSS and family formation questionnaires. Descriptive statistics, univariate parameter-constraints, and correlation analyses examined relations among study variables. Ongoing intrusive thoughts and hyperarousal were negatively linked to family identity development and family achievement. Findings from the present study provide support that ongoing CR-PTSS may be a barrier to family formation. © 2018 Wiley Periodicals, Inc.

Point-of-care ultrasonography by pediatric emergency physicians. Policy statement.

PubMed

Marin, Jennifer R; Lewiss, Resa E

2015-04-01

Point-of-care ultrasonography is increasingly being used to facilitate accurate and timely diagnoses and to guide procedures. It is important for pediatric emergency physicians caring for patients in the emergency department to receive adequate and continued point-of-care ultrasonography training for those indications used in their practice setting. Emergency departments should have credentialing and quality assurance programs. Pediatric emergency medicine fellowships should provide appropriate training to physician trainees. Hospitals should provide privileges to physicians who demonstrate competency in point-of-care ultrasonography. Ongoing research will provide the necessary measures to define the optimal training and competency assessment standards. Requirements for credentialing and hospital privileges will vary and will be specific to individual departments and hospitals. As more physicians are trained and more research is completed, there should be one national standard for credentialing and privileging in point-of-care ultrasonography for pediatric emergency physicians.

2015 Fermilab Laboratory Directed Research & Development Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Wester, W.

2016-05-26

The Fermi National Accelerator Laboratory (FNAL) is conducting a Laboratory Directed Research and Development (LDRD) program. Fiscal year 2015 represents the first full year of LDRD at Fermilab and includes seven projects approved mid-year in FY14 and six projects approved in FY15. One of the seven original projects has been completed just after the beginning of FY15. The implementation of LDRD at Fermilab is captured in the approved Fermilab 2015 LDRD Annual Program Plan. In FY15, the LDRD program represents 0.64% of Laboratory funding. The scope of the LDRD program at Fermilab will be established over the next couple ofmore » years where a portfolio of about 20 on-going projects representing approximately between 1% and 1.5% of the Laboratory funding is anticipated. This Annual Report focuses on the status of the current projects and provides an overview of the current status of LDRD at Fermilab.« less

"There is One Geometry and in Each Case There is a Different Formula". Students' Conceptions and Strategies in an Attempt of Producing a Minkowskian Metric on Space-Time

NASA Astrophysics Data System (ADS)

Rizos, Ioannis; Patronis, Anastasios (Tasos); Lappas, Dionyssios

2017-08-01

In this paper, we analyze two episodes from an inquiry-based didactical research; the complete analysis of our research data is still ongoing. By taking into consideration various developments from the history of the geometry of space-time, our general aim is to explore high school students' conceptions about measurement of length and time in relatively moving systems, and lead the students to reconsider these conceptions in an attempt of constructing a new metric for space-time. The episodes are extracted from long (focused) interviews with two couples of students, based on a carefully designed fictional scenario. Two main strategies have been identified and are analyzed in the paper: one of them relies on imagination and intuition; the other one makes use of preexisting school mathematical knowledge, in arriving to a simplified formula of a Minkowskian metric.

Qualitative and mixed methods research in dissemination and implementation science: introduction to the special issue.

PubMed

Southam-Gerow, Michael A; Dorsey, Shannon

2014-01-01

This special issue provides examples of how qualitative and mixed methods research approaches can be used in dissemination and implementation science. In this introductory article, we provide a brief rationale for why and how qualitative and mixed methods approaches can be useful in moving the field forward. Specifically, we provide a brief primer on common qualitative methods, including a review of guidelines provided by the National Institutes of Health. Next, we introduce the six articles in the issue. The first of the articles by Palinkas represents a more thorough and authoritative discussion related to qualitative methods, using the other five articles in the issue (and other published works) as examples. The remaining five articles are empirical and/or descriptive articles of recently completed or ongoing qualitative or mixed methods studies related to dissemination and implementation of evidence-based practices for children and adolescents.

EarthScope's Plate Boundary Observatory in Alaska: Building on Existing Infrastructure to Provide a Platform for Integrated Research and Hazard-monitoring Efforts

NASA Astrophysics Data System (ADS)

Boyce, E. S.; Bierma, R. M.; Willoughby, H.; Feaux, K.; Mattioli, G. S.; Enders, M.; Busby, R. W.

2014-12-01

EarthScope's geodetic component in Alaska, the UNAVCO-operated Plate Boundary Observatory (PBO) network, includes 139 continuous GPS sites and 41 supporting telemetry relays. These are spread across a vast area, from northern AK to the Aleutians. Forty-five of these stations were installed or have been upgraded in cooperation with various partner agencies and currently provide data collection and transmission for more than one group. Leveraging existing infrastructure normally has multiple benefits, such as easier permitting requirements and costs savings through reduced overall construction and maintenance expenses. At some sites, PBO-AK power and communications systems have additional capacity beyond that which is needed for reliable acquisition of GPS data. Where permits allow, such stations could serve as platforms for additional instrumentation or real-time observing needs. With the expansion of the Transportable Array (TA) into Alaska, there is increased interest to leverage existing EarthScope resources for station co-location and telemetry integration. Because of the complexity and difficulty of long-term O&M at PBO sites, however, actual integration of GPS and seismic equipment must be considered on a case-by-case basis. UNAVCO currently operates two integrated GPS/seismic stations in collaboration with the Alaska Earthquake Center, and three with the Alaska Volcano Observatory. By the end of 2014, PBO and TA plan to install another four integrated and/or co-located geodetic and seismic systems. While three of these are designed around existing PBO stations, one will be a completely new TA installation, providing PBO with an opportunity to expand geodetic data collection in Alaska within the limited operations and maintenance phase of the project. We will present some of the design considerations, outcomes, and lessons learned from past and ongoing projects to integrate seismometers and other instrumentation at PBO-Alaska stations. Developing the PBO network as a platform for ongoing research and hazard monitoring equipment may also continue to serve the needs of the research community and the public beyond the sun-setting and completion of EarthScope science plan in 2018.

Ongoing training of community health workers in low-income andmiddle-income countries: a systematic scoping review of the literature.

PubMed

O'Donovan, James; O'Donovan, Charles; Kuhn, Isla; Sachs, Sonia Ehrlich; Winters, Niall

2018-04-28

Understanding the current landscape of ongoing training for community health workers (CHWs) in low-income and middle-income countries (LMICs) is important both for organisations responsible for their training, as well as researchers and policy makers. This scoping review explores this under-researched area by mapping the current delivery implementation and evaluation of ongoing training provision for CHWs in LMICs. Systematic scoping review. MEDLINE, Embase, AMED, Global Health, Web of Science, Scopus, ASSIA, LILACS, BEI and ERIC. Original studies focusing on the provision of ongoing training for CHWs working in a country defined as low income and middle income according to World Bank Group 2012 classification of economies. The scoping review found 35 original studies that met the inclusion criteria. Ongoing training activities for CHWs were described as supervision (n=19), inservice or refresher training (n=13) or a mixture of both (n=3). Although the majority of studies emphasised the importance of providing ongoing training, several studies reported no impact of ongoing training on performance indicators. The majority of ongoing training was delivered inperson; however, four studies reported the use of mobile technologies to support training delivery. The outcomes from ongoing training activities were measured and reported in different ways, including changes in behaviour, attitudes and practice measured in a quantitative manner (n=16), knowledge and skills (n=6), qualitative assessments (n=5) or a mixed methods approach combining one of the aforementioned modalities (n=8). This scoping review highlights the diverse range of ongoing training for CHWs in LMICs. Given the expansion of CHW programmes globally, more attention should be given to the design, delivery, monitoring and sustainability of ongoing training from a health systems strengthening perspective. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Results of the 2004 Distance Education Survey: Summary Findings of Respondents (Students and Faculty/Staff) District-Wide

ERIC Educational Resources Information Center

Glyer-Culver, Betty

2005-01-01

Results of two web-based surveys, one completed by students and one completed by faculty, staff and managers in Fall 2004, which were designed to provide information to assist with ongoing discussions surrounding the future of Distance Education at each of the colleges in the Los Rios Community College District-American River College, Cosumnes…

Class@Baikal: the Endurance of the UNESCO Training-Through-Research Programme

NASA Astrophysics Data System (ADS)

Mazzini, A.; Akhmanov, G.; Khlystov, O.; Tokarev, M.; Korost, D. V.; Poort, J.; Fokina, A.; Giliazetdinova, D. R.; Yurchenko, A.; Vodopyanov, S.

2014-12-01

In July 2014, by the initiative of the Moscow State University and Limnological Institute of Russian Academy of Sciences, the first Training-through-Research Class@Baikal was launched in Lake Baikal, Russia. The cruise program focused on seafloor sampling and acoustic investigations of gas seeps, flares, mud volcanoes, slumps and debris flows, canyons and channels in the coastal proximity. A comprehensive multidisciplinary program to train students has been developed to cover sedimentology, fluid geochemistry, biology, geophysics and marine geology in general. Daily lectures were conducted on board by academics presenting pertinent research projects, and cruise planning and preliminary results were discussed with all the scientific crew. A daily blog with updates on the expedition activities, images, and ongoing cruise results, was also completed (i.e. visit the cruise blog: http://baikal.festivalnauki.ru/) and gave the opportunity to interact with experts as well as attract the interest also of a broader audience. This project is a follow up to the well-established UNESCO Training-through-Research (TTR) Floating University Programme (http://floatinguniversity.ru/) that covered large areas on the European and arctic margins since 1991 with 18 research cruises attended by about 1000 BSc, MSc and PhD students from Europe, Asia, Africa and America. The crucial goal of both programmes is the training of new generations of scientists through active research directly on the field. Students can access the collected data and samples for their Master and PhD projects. Typically an extensive set of analyses and data processing is completed in-house and the results and interpretations are presented at post cruise meetings and international conferences. The Baikal lake is 25 million years old rift zone and provides a large variety of active geological features that can be easily reached at daily sailing distance. This represents an extraordinary opportunity to switch and focus on different disciplines and processes. We envisage extending the duration of the following expeditions completing several crew changes in order to broaden the international cooperation.

Natural resource inventories and management applications in the Great Basin. [Nevada vegetation and wildlands

NASA Technical Reports Server (NTRS)

Tueller, P. T.; Lorain, G.; Halvorson, R. M.

1974-01-01

ERTS-1 resolution capabilities and repetitive coverage have allowed the acquisition of several statewide inventories of natural resource features not previously completed or that could not be completed in any other way. Familiarity with landform, tone, pattern and other converging factors, along with multidate imagery, has been required. Nevada's vegetation has been mapped from ERTS-1. Dynamic characteristics of the landscape have been studied. Sequential ERTS-1 imagery has proved its usefulness for mapping vegetation, following vegetation phenology changes, monitoring changes in lakes and reservoirs (including water quality), determining changes in surface mining use, making fire fuel estimates and determining potential hazard, mapping the distribution of rain and snow events, making range readiness determinations, monitoring marshland management practices and other uses. Feasibility has been determined, but details of incorporating the data in management systems awaits further research and development. The need is to accurately define the steps necessary to extract required or usable information from ERTS imagery and fit it into on-going management programs.

GO1 Inert Test Article Captive Carry

NASA Image and Video Library

2018-01-10

Generation Orbit Launch Services, Inc. (GO) completed the GO1 Inert Test Article captive carry flight test at NASA’s Armstrong Flight Research Center in December. Under a public-private partnership with NASA, GO developed the GO1-ITA, a mass properties and outer mold line simulator for the GO1 hypersonic flight testbed and earned NASA airworthiness approval for flight on NASA’s C-20a. NASA’s C-20a was originally modified to add a centerline hard point to carry the Uninhabited Aerial Vehicle Synthetic Aperture Radar (UAVSAR) pod. Together with the NASA Armstrong team, a campaign of three flight tests was conducted, successfully completing all test objectives including clearing the operational flight envelope of the C-20a with the GO1-ITA mounted to the centerline hard point, and demonstrated the unique launch maneuver designed for air launch of the GO1 on operational flights starting in 2019. Data collected during the campaign will be used to validate models and inform the ongoing design and development of GO1.

A Pilot Study to Test the Efficacy of Psychologically Based Physical Therapy Training for Treating Deployed U.S. Sailors and Marines with Musculoskeletal Injuries

DTIC Science & Technology

2015-10-01

questionnaires………………………………………………………………...8 Procedures for completing SOAP note………………………………………………………………………………………….8 Procedures for scanning consent...questionnaire and SOAP note data………………………………………….9 Procedures for collecting on-going treatment data………………………………………………………………….……9 Procedures for...accuracy of data collection; f. Completion of SOAP notes; g. Handling, storing and transferring research data; h. Reporting of adverse events; i

Ongoing daytime behavioural problems in university students following childhood mild traumatic brain injury.

PubMed

Albicini, Michelle S; Lee, James; McKinlay, Audrey

2016-03-01

Sleep is often disrupted in traumatic brain injury (TBI) and may be related to persistent behaviour problems; however, little is known about this relationship in young adults. This study explored associations between TBI, behavioural problems and sleep disturbances in 247 university students (197 non-TBI, 47 mild TBI, two moderate TBI, one severe TBI) aged 18-25 years, who completed validated measures for behaviour, sleep quality and history of TBI. Because of small group numbers, participants reporting moderate to severe TBI were excluded from the analyses. Results indicated that students with mild TBI reported higher levels of daytime dysfunction, somatic complaints, withdrawal, other behavioural complaints and internalizing behaviours compared with students with no TBI history. A correlational analysis indicated a moderate relationship between the above significant variables. Our results suggest that university students with a history of mild TBI are more likely to experience certain ongoing daytime behavioural problems, which are likely to negatively influence their academic functioning in tertiary education. This study highlights the importance of research on long-term problems following mild TBI in young adults aged 18-25 years--an age group often overlooked within the literature.

Integrated Cancer Research in Five Thematic Areas in Interest

DTIC Science & Technology

2005-07-01

Professor of Urology (on-going RSU), Howard Crawford, PhD, Assistant Professor of Pharmacological Sciences (on-going RSU), Marjana Maletic- Savatic ...young scientists. Drs. Adler, Crawford, Maletic- Savatic received base support from this mechanism as they further develop their research programs...Mirjana Maletic- Savatic , MD-PhD, Assistant Professor Neurology: Human Neural Stem Cells - In Vivo Models for Cerebral Carcinoma The study of human

A Qualitative Research on the University Administrators' Capacity to Use Management Knowledge Tools (The Case of TRNC Universities)

ERIC Educational Resources Information Center

Dagli, Gokmen; Silman, Fatos; Birol, Cem

2009-01-01

In order to reach goals and continue the ongoing learning process, like other organizations, universities also need the effective use of knowledge management. Knowledge management is an ongoing process and it has to be organized in a manner that is always open to new ideas. In universities where research and development studies play an important…

29 CFR 29.8 - Deregistration of a registered program.

Code of Federal Regulations, 2010 CFR

2010-07-01

... schedule of wages consistent with the apprentices skills acquired; or persistent and significant failure to... of several years, demonstrates an ongoing pattern of very low completion rates over a period of...

Research and Development initiative of Satellite Technology Application for Environmental Issues in Asia Region

NASA Astrophysics Data System (ADS)

Hamamoto, K.; Kaneko, Y.; Sobue, S.; Oyoshi, K.

2016-12-01

Climate change and human activities are directly or indirectly influence the acceleration of environmental problems and natural hazards such as forest fires, drought and floods in the Asia-Pacific countries. Satellite technology has become one of the key information sources in assessment, monitoring and mitigation of these hazards and related phenomenon. However, there are still gaps between science and application of space technology in practical usage. Asia-Pacific Regional Space Agency Forum (APRSAF) recommended to initiate the Space Applications for Environment (SAFE) proposal providing opportunity to potential user agencies in the Asia Pacific region to develop prototype applications of space technology for number of key issues including forest resources management, coastal monitoring and management, agriculture and food security, water resource management and development user-friendly tools for application of space technology. The main activity of SAFE is SAFE prototyping. SAFE prototyping is a demonstration for end users and decision makers to apply space technology applications for solving environmental issues in Asia-Pacific region. By utilizing space technology and getting technical support by experts, prototype executers can develop the application system, which could support decision making activities. SAFE holds a workshop once a year. In the workshop, new prototypes are approved and the progress of on-going prototypes are confirmed. Every prototype is limited for two years period and all activities are operated by volunteer manner. As of 2016, 20 prototypes are completed and 6 prototypes are on-going. Some of the completed prototypes, for example drought monitoring in Indonesia were applied to operational use by a local official organization.

Evidence of lung cancer risk from animal studies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cross, F.T.

Human epidemiological data provide the most important basis for assessing risks of radon exposures. However, additional insight into the nature of exposure-response relationships is provided by animal experimentation and dosimetric determinations. Animal studies have now been conducted for more than 50 years to examine the levels of pollutants in underground mines that were responsible for the respiratory effects observed among miners. This work has emphasized respiratory cancer and the interaction of radon with other agents, such as ore dust, diesel-engine-exhaust fumes and cigarette smoke. The more recent data on radon-daughter inhalation exposures were provided by two American research centers, Themore » University of Rochester (UR) and the Pacific Northwest Laboratory (PNL), and by the Compagnie Generale des Matieres Nucleaires (COGEMA) laboratory in France. Approximately 2000 mice, 100 rats and 80 dogs were employed in the completed UR studies, begun in the mid 1950s; 800 hamsters, 5000 rats and 100 dogs in the ongoing PNL studies, begun in the late 1960s; and 10,000 rats in the ongoing COGEMA studies, also begun in the late 1960s. More complete updated biological effects, data resulting from chronic radon-daughter inhalation exposures of mice, hamsters, rats and beagle dogs were examined. Emphasis on the carcinogenic effects of radon-decay product exposure, including the influences of radon-daughter exposure rate, unattached fraction and disequilibrium, and co-exposures to other pollutants. Plausible values for the radon (radon-daughter) lifetime lung-cancer risk coefficients are also provided. 13 refs., 1 fig., 1 tab.« less

Environmental Development Plan (EDP). Enhanced gas recovery, FY 1977

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

1978-03-01

This Enhanced Gcs Recovery EDP addresses the environmental impacts of enhanced gas recovery processes in shale and sandstone, methane drainage from coalbeds, and methane recovery from geopressured aquifers. The EDP addresses planning in two basic areas: environmental research and environmental assessment. Environmental research can be categorized as follows: characterization of pollutants from EGR processes; selective application of monitoring and measuring techniques; evaluation of control/mitigation techniques; and evaluation of the synergistic impacts of the development of EGR techniques. Environmental assessment activities scheduled by EDP include: assessment of ecological impacts; assessment of socioeconomic effects; EIA/EIS preparation; evaluation of control technology needs; andmore » analysis of applicable and proposed emission, effluent, and health and safety standards. The EGR EDP includes an EGR technology overview (Section 2), a discussion of EGR environmental issues and requirements (Section 3), an environmental action plan (Section 4), an environmental management strategy for the EGR program (Section 5), and supporting appendices which present information on Federal legislation applicable to EGR technology, a summary of ongoing and completed research, and future research and assessment projects.« less

Exploration-Related Research on the International Space Station: Connecting Science Results to the Design of Future Missions

NASA Technical Reports Server (NTRS)

Rhatigan, Jennifer L.; Robinson, Julie A.; Sawin, Charles F.; Ahlf, Peter R.

2005-01-01

In January, 2004, the US President announced a vision for space exploration, and charged NASA with utilizing the International Space Station (ISS) for research and technology targeted at supporting the US space exploration goals. This paper describes: 1) what we have learned from the first four years of research on ISS relative to the exploration mission, 2) the on-going research being conducted in this regard, 3) our current understanding of the major exploration mission risks that the ISS can be used to address, and 4) current progress in realigning NASA s research portfolio for ISS to support exploration missions. Specifically, we discuss the focus of research on solving the perplexing problems of maintaining human health on long-duration missions, and the development of countermeasures to protect humans from the space environment, enabling long duration exploration missions. The interchange between mission design and research needs is dynamic, where design decisions influence the type of research needed, and results of research influence design decisions. The fundamental challenge to science on ISS is completing experiments that answer key questions in time to shape design decisions for future exploration. In this context, exploration-relevant research must do more than be conceptually connected to design decisions-it must become a part of the mission design process.

Why female sex workers participate in HIV research: the illusion of voluntariness.

PubMed

Reed, Elizabeth; Fisher, Celia B; Blankenship, Kim M; West, Brooke S; Khoshnood, Kaveh

2017-07-01

The purpose of this study was to examine factors influencing the motivation for and perceived voluntariness of participation in non-intervention HIV research among female sex workers (FSW) in India. FSW (n = 30) who participated in non-intervention HIV studies in the previous three years were recruited from a local community-based organization. Semi-structured qualitative interviews focused on women's personal and economic motivations for participation and their perceptions of the informed consent process. Interviews were audio-recorded, translated, transcribed, and reviewed for common themes. Content analysis indicated that while many women reported willing participation, reports of obligatory participation were also a common theme. Obligations included money-related pressures and coercion by other FSW, social pressures, not wanting to disappoint the researchers, and perceiving that they had a contractual agreement to complete participation as a result of signing the consent form. Findings suggest a need for additional efforts during and following informed consent to prevent obligatory participation in HIV research studies among FSW. Findings emphasize the importance of integrating ongoing participant feedback into research ethics practices to identify issues not well addressed via standard ethics protocols when conducting HIV research among vulnerable populations.

Overview of bureau research directed towards surface powered haulage safety

DOE Office of Scientific and Technical Information (OSTI.GOV)

May, J.P.; Aldinger, J.A.

1995-12-31

Surface mining operations, including mills and preparation plants, employ over 260,000 people. This represents a significant contribution to our nation`s economy and an important source of skilled and well-paying jobs. As mine production has shifted from underground to surface, and with continuing advances in underground mine safety, surface mining has unfortunately become the leader in mine fatalities. In 1994 surface mining accidents accounted for 49% of all mine fatalities, followed by underground mining with 37% and mills and preparation plants with 14%. The U.S. Bureau of Mines (USBM) has targeted surface mining as an important research priority to reduce themore » social and economic costs associated with fatalities and lost-work-time injuries. USBM safety research focuses on the development of technologies that can enhance productivity and reduce mining costs through a reduction in the number and severity of mining accidents. This report summarizes a number of completed and ongoing research programs directed towards surface powered haulage--the single largest category of fatalities in surface mining and a major cause of lost workdays. Research products designed for industry are highlighted and future USBM surface mining safety research is discussed.« less

Improved tank car design development : ongoing studies on sandwich structures

DOT National Transportation Integrated Search

2009-03-02

The Government and industry have a common interest in : improving the safety performance of railroad tank cars carrying : hazardous materials. Research is ongoing to develop strategies : to maintain the structural integrity of railroad tank cars carr...

Older Adults Exposed to Ongoing versus Intense Time-Limited Missile Attacks: Differences in Symptoms of Posttraumatic Stress Disorder.

PubMed

Shrira, Amit; Shmotkin, Dov; Palgi, Yuval; Hoffman, Yaakov; Bodner, Ehud; Ben-Ezra, Menachem; Litwin, Howard

2017-01-01

The potentially different psychological effects of ongoing trauma vis-à-vis an intense time-limited exposure to trauma have not been examined in older adults. Therefore, this study examined posttraumatic stress disorder (PTSD) symptoms and their health concomitants in two groups of older adults in Israel: those exposed to ongoing missile attacks and those exposed to an intense time-limited period of missile attacks. In the third administration of the Israeli component of the Survey of Health, Ageing, and Retirement in Europe (SHARE-Israel), 297 older adults reported ongoing exposure to missile attacks due to the Israel-Gaza conflict (mean age = 66.97), while 309 older adults reported exposure to an intense period of missile attacks during the Second Lebanon War (mean age = 66.63). Participants completed measures of PTSD symptoms, and physical, cognitive, and mental health. Older adults with ongoing exposure reported higher PTSD symptom level relative to those with intense time-limited exposure. The groups also differed in health variables related to PTSD symptoms. Namely, impaired physical and cognitive health were related to a higher level of PTSD symptoms in ongoing exposure, while impaired mental health was related to a higher PTSD symptom level following intense time-limited exposure. The findings suggest that physical and cognitive health involves resources that are vital for daily survival when living under ongoing warfare threat, whereas mental health involves resources that are needed in dealing with psychological effects of warfare trauma. Accordingly, different interventions may be necessary when helping older adults exposed to ongoing versus intense time-limited trauma.

Structural mapping from MSS-LANDSAT imagery: A proposed methodology for international geological correlation studies

NASA Technical Reports Server (NTRS)

Dejesusparada, N. (Principal Investigator); Crepani, E.; Martini, P. R.

1980-01-01

A methodology is proposed for international geological correlation studies based on LANDSAT-MSS imagery, Bullard's model of continental fit and compatible structural trends between Northeast Brazil and the West African counterpart. Six extensive lineaments in the Brazilian study area are mapped and discussed according to their regional behavior and in relation to the adjacent continental margin. Among the first conclusions, correlations were found between the Sobral Pedro II Lineament and the megafaults that surround the West African craton; and the Pernambuco Lineament with the Ngaurandere Linemanet in Cameroon. Ongoing research to complete the methodological stages includes the mapping of the West African structural framework, reconstruction of the pre-drift puzzle, and an analysis of the counterpart correlations.

HDAC Inhibitors Target Replication Forks to Take a Stab at Cancer | Center for Cancer Research

Cancer.gov

The stability and function of many proteins within the cell can be altered with the addition or removal of certain chemical groups, including acetyl groups. Therefore, the enzymes that regulate these modifications have an important impact on the cell. One class of such enzymes—histone deacetylases, or HDACs—has been implicated in cancer and has become a target for cancer therapy. One HDAC inhibitor, called SAHA, has been approved for use against cutaneous T-cell lymphoma, and more than 60 ongoing clinical trials are continuing to test this class of drugs in various forms of cancer. However, the mechanisms by which SAHA and other HDAC inhibitors undermine the viability of tumor cells are not completely understood.

Artificial intelligence and space power systems automation

NASA Technical Reports Server (NTRS)

Weeks, David J.

1987-01-01

Various applications of artificial intelligence to space electrical power systems are discussed. An overview is given of completed, on-going, and planned knowledge-based system activities. These applications include the Nickel-Cadmium Battery Expert System (NICBES) (the expert system interfaced with the Hubble Space Telescope electrical power system test bed); the early work with the Space Station Experiment Scheduler (SSES); the three expert systems under development in the space station advanced development effort in the core module power management and distribution system test bed; planned cooperation of expert systems in the Core Module Power Management and Distribution (CM/PMAD) system breadboard with expert systems for the space station at other research centers; and the intelligent data reduction expert system under development.

75 FR 27990 - New England Fishery Management Council; Public Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2010-05-19

... Amendment 2 DEIS. As time permits and pending completion of analyses by the PDT, discuss ongoing PDT work and recommendations related to deep- sea coral protection areas, Habitat Areas of Particular Concern...

DOE Radiation Research Program is floundering - NAS

DOE Office of Scientific and Technical Information (OSTI.GOV)

Lobsenz, G.

1994-04-20

The Energy Department's radiation health effects research program is floundering in a morass of administrative confusion due to an ill-considered 1990 joint management agreement between DOE and the Health and Human Services Department, a National Academy of Sciences panel says. The NAS panel said the [open quotes]administrative difficulties[close quotes] created by the DOE-HHS agreement appear to be [open quotes]stifling creativity and efficiency within DOE's Epidemiology Research Program, delaying the completion and publication of research.[close quotes] The panel also expressed concern that DOE has failed to adequately fund or staff its health research office, and that the department had no mastermore » research plan to identify research needs or set forth uniform, scientifically rigorous data collection procedures. The panel said DOE's lack of commitment was particularly evident in its failure to set up an effective health surveillance program for its nuclear work force. In addition, the panel said DOE had fallen short on promises to create a comprehensive computer bank of health research data that would be continually updated with new information gleaned from an ongoing worker surveillance program. While recommending enhancements, the NAS panel emphasized that DOE's health research program would not be able to function effectively until the department revamped its joint management agreement with HHS.« less

Tech notes: Ongoing or planned hydro research, results of recent studies, and reviews of new books, publications, and software

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Ongoing or planned hydro research, results of recent studies, and reviews of new books, publications, and software are covered. This month`s Tech Notes include: (1) a study linking development and reservoir silting in El Salvador, (2) publication of a guide for small hydro operatos, and (3) publication of a text outlining the development of hydroelectric power in Russia.

Control and Diagnosis in Integrated Product Development - Observations during the Development of an AGV

NASA Astrophysics Data System (ADS)

Stetter, R.; Simundsson, A.

2015-11-01

This paper is concerned with the integration of control and diagnosis functionalities into the development of complete systems which include mechanical, electrical and electronic subsystems. For the development of such systems the strategies, methods and tools of integrated product development have attracted significant attention during the last decades. Today, it is generally observed that product development processes of complex systems can only be successful if the activities in the different domains are well connected and synchronised and if an ongoing communication is present - an ongoing communication spanning the technical domains and also including functions such as production planning, marketing/distribution, quality assurance, service and project planning. Obviously, numerous approaches to tackle this challenge are present in scientific literature and in industrial practice, as well. Today, the functionality and safety of most products is to a large degree dependent on control and diagnosis functionalities. Still, there is comparatively little research concentrating on the integration of the development of these functionalities into the overall product development processes. The main source of insight of the presented research is the product development process of an Automated Guided Vehicle (AGV) which is intended to be used on rough terrain. The paper starts with a background describing Integrated Product Development. The second section deals with the product development of the sample product. The third part summarizes some insights and formulates first hypotheses concerning control and diagnosis in Integrated Product Development.

Design methodology and projects for space engineering

NASA Technical Reports Server (NTRS)

Nichols, S.; Kleespies, H.; Wood, K.; Crawford, R.

1993-01-01

NASA/USRA is an ongoing sponsor of space design projects in the senior design course of the Mechanical Engineering Department at The University of Texas at Austin. This paper describes the UT senior design sequence, consisting of a design methodology course and a capstone design course. The philosophical basis of this sequence is briefly summarized. A history of the Department's activities in the Advanced Design Program is then presented. The paper concludes with a description of the projects completed during the 1991-92 academic year and the ongoing projects for the Fall 1992 semester.

Cell module and fuel conditioner

NASA Technical Reports Server (NTRS)

Hoover, D. Q., Jr.

1981-01-01

The results of the completed tests on Stack 561 and the on-going tests of 562 (23 cell stacks of the MK-1 and M-2 designs respectively) are reported and their performance is compared. Results of the on-going endurance test of Stack 560 (5 cell, MK-2) are reported. Plans for fabrication of Stacks 563 and 564 (23 cell stacks of the MK-1 and MK-2 design) are summarized. Results of the burner tests are given. Excellent performance was achieved on simulated anode exhaust gas over very wide load and air/fuel ranges.

International Space Station Research: Accomplishments and Pathways for Exploration and Fundamental Research

NASA Technical Reports Server (NTRS)

Robinson, Julie A.

2007-01-01

Beginning with the launch of the European Columbus module planned for December 2007, we approach a transition in the assembly of the International Space Station (ISS) that is of great importance for the sciences. During the following 18 months, we will operate the first experiments in Columbus physical science resource facilities and also launch and commission the Japanese Kibo module. In addition, two Multi-purpose Logistics Module (MPLM) flights will deliver the U.S. Combustion Integrated Rack (CIR) and Fluids Integrated Rack (FIR) along with their first science experiments. These facilities provide significant new capabilities for basic and applied physical science research in microgravity. New life support technologies will come online throughout 2008, and we will reach the milestone of a 6-person crew planned for April 2009. A larger crew enables significant more scientific use of all the facilities for the life of ISS. Planning for the use of the International Space Station as a national laboratory is also maturing as we near the completion of assembly, enabling access to ISS as a research platform for other government agencies and the private sector. The latest updates on National Laboratory implementation will also be provided in this presentation. At the same time as these significant increases in scientific capability, there have been significant ongoing accomplishments in NASA's early ISS research both exploration related and fundamental research. These accomplishments will be reviewed in context as harbingers of the capabilities of the International Space Station when assembly is complete. The Vision for Space Exploration serves to focus NASA's applied investigations in the physical sciences. However, the broader capability of the space station as a National Laboratory and as a nexus for international collaboration will also influence the study of gravity-dependent processes by researchers around the world.

Implementing a Primary Prevention Social Skills Intervention in Urban Preschools: Factors Associated with Quality and Fidelity

PubMed Central

Wenz-Gross, Melodie; Upshur, Carole

2012-01-01

Research Findings Preschool behavior problems are of increasing concern to early childhood educators. Preventive interventions are being developed, but implementation in under-resourced child care programs is challenging. This study describes the implementation of an adapted Second Step curriculum to increase children’s social skills and decrease behavior problems in preschool classrooms. Teacher training/coaching, organizational supports, and procedures for sustainability are described. Measures included baseline classroom characteristics, lesson completion and fidelity, and teacher satisfaction. Teachers completed 88% of the lessons across two years. Follow-up monitoring in Year 3, once all training was terminated, found 95% of lessons were delivered with higher fidelity than the first two years. Teachers were satisfied with training, felt the curriculum improved children’s social skills, and stated they would continue to use the curriculum. Lesson completion and fidelity were associated with various teacher characteristics, training attendance, classroom characteristics, teacher and child turnover, and the percent of children with developmental delays in the classroom. Practice Results support the implementation strategy and suggest that paying attention to teacher morale, general skill development, and a period of on-going support for training is important and will lead to sustainable and high implementation rates. PMID:22791957

Advanced Course Offerings and Completion in Science, Technology, Engineering, and Math in Texas Public High Schools. REL 2018-276

ERIC Educational Resources Information Center

Garland, Marshall; Rapaport, Amie

2017-01-01

Taking advanced high school courses predicts such postsecondary outcomes as enrolling in college, persisting in college courses, and completing a degree. In Texas, where Hispanic students make up 51 percent of the student population, their access to and enrollment in advanced courses is an ongoing concern despite recent gains. In particular,…

An ongoing process: a qualitative study of how the alcohol-dependent free themselves of addiction through progressive abstinence.

PubMed

Yeh, Mei-Yu; Che, Hui-Lian; Wu, Shu-Mei

2009-11-24

Most people being treated for alcoholism are unable to successfully quit drinking within their treatment programs. In few cases do we know the full picture of how abstinence is achieved in Taiwan. We tracked processes of abstinence in alcohol-dependency disorders, based on study evidence and results. This research explores the process of recovery from the viewpoint of the alcohol-dependent. Semi-structured interviews were conducted in two different settings, using purpose sampling, during 2003-2004. The data were analyzed using content analysis. Participants were 32 adults, purposefully selected from an Alcoholics Anonymous group and a psychiatric hospital in North Taiwan. We found that the abstinence process is an ongoing process, in which the alcohol-dependent free themselves of addiction progressively. This process never ends or resolves in complete recovery. We have identified three stages in the struggle against alcoholism: the Indulgence, Ambivalence and Attempt (IAA) cycle, in which the sufferer is trapped in a cycle of attempting to give up and failing; the Turning Point, in which a Personal Nadir is reached, and the Ongoing Process of abstinence, in which a constant effort is made to remain sober through willpower and with the help of support groups. We also discuss Influencing Factors that can derail abstinence attempts, pushing the sufferer back into the IAA cycle. This study provides important points of reference for alcohol and drug service workers and community healthcare professionals in Taiwan, casting light on the abstinence process and providing a basis for intervention or rehabilitation services.

Adversity, time, and well-being: A longitudinal analysis of time perspective in adulthood.

PubMed

Holman, E Alison; Silver, Roxane Cohen; Mogle, Jacqueline A; Scott, Stacey B

2016-09-01

Despite the prominence of time in influential aging theories and the ubiquity of stress across the life span, research addressing how time perspective (TP) and adversity are associated with well-being across adulthood is rare. Examining the role of TP in coping with life events over the life span would be best accomplished after large-scale population-based exposure to a specific event, with repeated assessments to examine within- and between-person differences over time. A national sample aged 18-91 years (N = 722, M = 49.4 years) was followed for 3 years after the September 11, 2001 (9/11) terrorist attacks. Respondents completed assessments of 9/11-related television (TV) exposure 9-21 days after the attacks, temporal disintegration 2 months post-9/11, and TP, ongoing stress, and well-being at 12, 24, and 36 months post-9/11. Results provided support for measurement invariance of TP across time and across age. Early 9/11-related TV exposure was significantly associated with greater temporal disintegration. Temporal disintegration and ongoing stress, in turn, were associated with between- and within-person variation in past TP. This effect was qualified by an age interaction that indicated a stronger relationship between ongoing stress and past TP for younger compared with older adults. Past and future TP were significantly and independently related to individual differences and within-person variation in psychological well-being, regardless of age. Future work should incorporate adversity as an important correlate of TP across adulthood. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

An ongoing process: A qualitative study of how the alcohol-dependent free themselves of addiction through progressive abstinence

PubMed Central

2009-01-01

Background Most people being treated for alcoholism are unable to successfully quit drinking within their treatment programs. In few cases do we know the full picture of how abstinence is achieved in Taiwan. We tracked processes of abstinence in alcohol-dependency disorders, based on study evidence and results. This research explores the process of recovery from the viewpoint of the alcohol-dependent. Methods Semi-structured interviews were conducted in two different settings, using purpose sampling, during 2003-2004. The data were analyzed using content analysis. Participants were 32 adults, purposefully selected from an Alcoholics Anonymous group and a psychiatric hospital in North Taiwan. Results We found that the abstinence process is an ongoing process, in which the alcohol-dependent free themselves of addiction progressively. This process never ends or resolves in complete recovery. We have identified three stages in the struggle against alcoholism: the Indulgence, Ambivalence and Attempt (IAA) cycle, in which the sufferer is trapped in a cycle of attempting to give up and failing; the Turning Point, in which a Personal Nadir is reached, and the Ongoing Process of abstinence, in which a constant effort is made to remain sober through willpower and with the help of support groups. We also discuss Influencing Factors that can derail abstinence attempts, pushing the sufferer back into the IAA cycle. Conclusion This study provides important points of reference for alcohol and drug service workers and community healthcare professionals in Taiwan, casting light on the abstinence process and providing a basis for intervention or rehabilitation services. PMID:19930698

ADS-33C related handling qualities research performed using the NRC Bell 205 airborne simulator

NASA Technical Reports Server (NTRS)

Morgan, J. Murray; Baillie, Stewart W.

1993-01-01

Over 10 years ago a project was initiated by the U.S. Army AVSCOM to update the military helicopter flying qualities specification MIL-8501-A. While not yet complete, the project reached a major milestone in 1989 with the publication of an Airworthiness Design Standard, ADS-33C. The 8501 update project initially set out to identify critical gaps in the requisite data base and then proceeded to fill them using a variety of directed research studies. The magnitude of the task required that it become an international effort: appropriate research studies were conducted in Germany, the UK and Canada as well as in the USA. Canadian participation was supported by the Department of National Defence (DND) through the Chief of Research and Development. Both ground based and in-flight simulation were used to study the defined areas and the Canadian Bell 205-A1 variable stability helicopter was used extensively as one of the primary research tools available for this effort. This paper reviews the involvement of the Flight Research Laboratory of the National Research Council of Canada in the update project, it describes the various experiments conducted on the Airborne Simulator, it notes significant results obtained and describes ongoing research associated with the project.

Coast Guard : budget challenges for 2001 and beyond

DOT National Transportation Integrated Search

2000-03-15

The testimony today, which is based on recently completed and ongoing work, addresses two topics: (1) the Coast Guard's progress in justifying and managing its Deepwater Project and (2) opportunities for improving the Coast Guard's operating efficien...

Creating a High-Frequency Electronic Database in the PICU: The Perpetual Patient.

PubMed

Brossier, David; El Taani, Redha; Sauthier, Michael; Roumeliotis, Nadia; Emeriaud, Guillaume; Jouvet, Philippe

2018-04-01

Our objective was to construct a prospective high-quality and high-frequency database combining patient therapeutics and clinical variables in real time, automatically fed by the information system and network architecture available through fully electronic charting in our PICU. The purpose of this article is to describe the data acquisition process from bedside to the research electronic database. Descriptive report and analysis of a prospective database. A 24-bed PICU, medical ICU, surgical ICU, and cardiac ICU in a tertiary care free-standing maternal child health center in Canada. All patients less than 18 years old were included at admission to the PICU. None. Between May 21, 2015, and December 31, 2016, 1,386 consecutive PICU stays from 1,194 patients were recorded in the database. Data were prospectively collected from admission to discharge, every 5 seconds from monitors and every 30 seconds from mechanical ventilators and infusion pumps. These data were linked to the patient's electronic medical record. The database total volume was 241 GB. The patients' median age was 2.0 years (interquartile range, 0.0-9.0). Data were available for all mechanically ventilated patients (n = 511; recorded duration, 77,678 hr), and respiratory failure was the most frequent reason for admission (n = 360). The complete pharmacologic profile was synched to database for all PICU stays. Following this implementation, a validation phase is in process and several research projects are ongoing using this high-fidelity database. Using the existing bedside information system and network architecture of our PICU, we implemented an ongoing high-fidelity prospectively collected electronic database, preventing the continuous loss of scientific information. This offers the opportunity to develop research on clinical decision support systems and computational models of cardiorespiratory physiology for example.

Refocusing research priorities in schools of nursing.

PubMed

Kulage, Kristine M; Ardizzone, Laura; Enlow, William; Hickey, Kathleen; Jeon, Christie; Kearney, Joan; Schnall, Rebecca; Larson, Elaine L

2013-01-01

It is critical for schools of nursing to periodically reassess their scholarly programs to ensure that their conceptual framework and approaches address current challenges and enhance productivity. This article describes the process undertaken at Columbia University School of Nursing to evaluate scholarly enterprise so that it remains relevant and responsive to changing trends and to revise our research conceptual model to be reflective of the foci of our clinicians and researchers. As part of a larger strategic initiative, a two-phase Research Excellence Planning and Implementation Workgroup was convened, consisting of a broad representation of faculty and administrative staff, with an overall goal of expanding scholarly capacity. During Phase I, members developed measurable outcomes and tactics and revised the school's conceptual research model. In Phase II, the workgroup implemented and monitored tactics and presented final recommendations to the dean. To measure progress, faculty members completed a survey to establish baseline scholarship and collaboration with results indicating room for growth in interdisciplinary and inter-institutional collaboration. Ongoing assessment of outcomes includes Web-based tracking of scholarly activities and follow-up surveys to monitor expansion of faculty collaboration. We recommend this process to other schools committed to sustainable, increasingly relevant scholarship. Copyright © 2013 Elsevier Inc. All rights reserved.

Tech notes: Ongoing or planned hydro research, results of recent studies, and reviews of new books, publications, and software

DOE Office of Scientific and Technical Information (OSTI.GOV)

NONE

Ongoing or planned hydro research, results of recent studies, and reviews of new books, publications, and software. Items covered this month include: (1) a recommendation that dam designers give more consideration to earthquake resistance, (2) the development of a new wave rotor design, (3) the development of a small hydro database in China, and (4) an ICOLD bulletin on the optimization of constuction costs.

Base Realignment and Closure (BRAC) Cleanup Plan

DTIC Science & Technology

1995-01-01

remedial action (RA). A number of restoration-related compliance activities at Cameron Station have also been completed or are ongoing. These include...from the identification stage to completion of remedial actions and development of NFRAP documentation. Table 3-2 also lists the study area...5 4.1.3.2 Remediation Timelines and Documents ............. 4-6 4.1.4 Environmental Restoration Early Actions Strategy ........... 4-10 4.1.5 Remedy

In situ treatment of VOCs by recirculation technologies

DOE Office of Scientific and Technical Information (OSTI.GOV)

Siegrist, R.L.; Webb, O.F.; Ally, M.R.

1993-06-01

The project described herein was conducted by Oak Ridge National Laboratory (ORNL) to identify processes and technologies developed in Germany that appeared to have near-term potential for enhancing the cleanup of volatile organic compound (VOC) contaminated soil and groundwater at DOE sites. Members of the ORNL research team identified and evaluated selected German technologies developed at or in association with the University of Karlsruhe (UoK) for in situ treatment of VOC contaminated soils and groundwater. Project activities included contacts with researchers within three departments of the UoK (i.e., Applied Geology, Hydromechanics, and Soil and Foundation Engineering) during fall 1991 andmore » subsequent visits to UoK and private industry collaborators during February 1992. Subsequent analyses consisted of engineering computations, groundwater flow modeling, and treatment process modeling. As a result of these project efforts, two processes were identified as having near-term potential for DOE: (1) the vacuum vaporizer well/groundwater recirculation well and (2) the porous pipe/horizontal well. This document was prepared to summarize the methods and results of the assessment activities completed during the initial year of the project. The project is still ongoing, so not all facets of the effort are completely described in this document. Recommendations for laboratory and field experiments are provided.« less

Engineered nanomaterial risk. Lessons learnt from completed nanotoxicology studies: potential solutions to current and future challenges.

PubMed

Johnston, Helinor; Pojana, Giulio; Zuin, Stefano; Jacobsen, Nicklas Raun; Møller, Peter; Loft, Steffen; Semmler-Behnke, Manuela; McGuiness, Catherine; Balharry, Dominique; Marcomini, Antonio; Wallin, Håkan; Kreyling, Wolfgang; Donaldson, Ken; Tran, Lang; Stone, Vicki

2013-01-01

PARTICLE_RISK was one of the first multidisciplinary projects funded by the European Commission's Framework Programme that was responsible for evaluating the implications of nanomaterial (NM) exposure on human health. This project was the basis for this review which identifies the challenges that exist within the assessment of NM risk. We have retrospectively reflected on the findings of completed nanotoxicology studies to consider what progress and advances have been made within the risk assessment of NMs, as well as discussing the direction that nanotoxicology research is taking and identifying the limitations and failings of existing research. We have reflected on what commonly encountered challenges exist and explored how these issues may be resolved. In particular, the following is discussed (i) NM selection (ii) NM physico-chemical characterisation; (iii) NM dispersion; (iv) selection of relevant doses and concentrations; (v) identification of relevant models, target sites and endpoints; (vi) development of alternatives to animal testing; and (vii) NM risk assessment. These knowledge gaps are relatively well recognised by the scientific community and recommendations as to how they may be overcome in the future are provided. It is hoped that this will help develop better defined hypothesis driven research in the future that will enable comprehensive risk assessments to be conducted for NMs. Importantly, the nanotoxicology community has responded and adapted to advances in knowledge over recent years to improve the approaches used to assess NM hazard, exposure and risk. It is vital to learn from existing information provided by ongoing or completed studies to avoid unnecessary duplication of effort, and to offer guidance on aspects of the experimental design that should be carefully considered prior to the start of a new study.

An Evaluation of Trauma Focused Cognitive Behavioral Therapy for Children in Zambia

PubMed Central

Murray, Laura K; Familiar, Itziar; Skavenski, Stephanie; Jere, Elizabeth; Cohen, Judy; Imasiku, Mwiya; Mayeya, John; Bass, Judith K; Bolton, Paul

2013-01-01

Objectives To monitor and evaluate the feasibility of implementing Trauma Focused-Cognitive Behavioral Therapy (TF-CBT) to address trauma and stress-related symptoms in orphans and vulnerable children (OVC) in Zambia as part of ongoing programming within a non-governmental organization (NGO). Methods As part of ongoing programming, voluntary care-workers administered locally validated assessments to identify children who met criteria for moderate to severe trauma symptomatology. Local lay counselors implemented TF-CBT with identified families, while participating in ongoing supervision. Fifty-eight children and adolescents aged 5–18 completed the TF-CBT treatment, with pre- and post-assessments. Results The mean number of traumas reported by the treatment completers (N=58) was 4.11. Post assessments showed significant reductions in severity of trauma symptoms (p<0.0001), and severity of shame symptoms (p<0.0001). Conclusions Our results suggest that TF-CBT is a feasible treatment option in Zambia for OVC. A decrease in symptoms suggests that a controlled trial is warranted. Implementation factors monitored suggest that it is feasible to integrate and evaluate evidence-based mental health assessments and intervention into programmatic services run by an NGO in low/middle resource countries. Results also support the effectiveness of implementation strategies such as task shifting, and the apprenticeship model of training and supervision. PMID:23768939

Guide to Documenting and Managing Cost and Performance Information for Remediation Projects - Revised Version

EPA Pesticide Factsheets

This Guide to Documenting and Managing Cost and Performance Information for Remediation Projects provides the recommended procedures for documenting the results of completed and on-going full-scale and demonstration-scale remediation projects.

Science Production in Germany, France, Belgium, and Luxembourg: Comparing the Contributions of Research Universities and Institutes to Science, Technology, Engineering, Mathematics, and Health.

PubMed

Powell, Justin J W; Dusdal, Jennifer

2017-01-01

Charting significant growth in science production over the 20th century in four European Union member states, this neo-institutional analysis describes the development and current state of universities and research institutes that bolster Europe's position as a key region in global science. On-going internationalization and Europeanization of higher education and science has been accompanied by increasing competition as well as collaboration. Despite the policy goals to foster innovation and further expand research capacity, in cross-national and historical comparison neither the level of R&D investments nor country size accounts completely for the differential growth of scientific productivity. Based on a comprehensive historical database from 1900 to 2010, this analysis uncovers both stable and dynamic patterns of production and productivity in Germany, France, Belgium, and Luxembourg. Measured in peer-reviewed research articles collected in Thomson Reuters' Science Citation Index Expanded, which includes journals in the fields of Science, Technology, Engineering, Mathematics, and Health, we show the varying contributions of different organizational forms, especially research universities and research institutes. Comparing the institutionalization pathways that created the conditions necessary for continuous and strong growth in scientific productivity in the European center of global science emphasizes that the research university is the key organizational form across countries.

Ongoing exposure versus intense periodic exposure to military conflict and terror attacks in Israel.

PubMed

Lahad, Mooli; Leykin, Dmitry

2010-12-01

The manifestation of posttraumatic stress disorder (PTSD) symptoms in two clinical samples in Israel (N = 212) was examined. Individuals suffering ongoing exposure to shelling were compared with subjects exposed to intense periodic exposure. Elevated arousal and avoidance symptoms, but not intrusion were reported in the ongoing exposure group. When compared by age, young participants in the ongoing exposure group had significantly lower PTSD scores, whereas no differences were found between participants among the intense periodic exposure age groups. No gender differences in symptoms were found among participants from intense periodic exposure, whereas in the other ongoing group the difference was in avoidance. Results are discussed in light of past research on exposure to terrorism. Copyright © 2010 International Society for Traumatic Stress Studies.

Green Infrastructure Research at EPA's Edison Environmental Center

EPA Science Inventory

The presentation outline includes: (1) Green infrastructure research objectives (2) Introduction to ongoing research projects - Aspects of design, construction, and maintenence that affect function - Real-world applications of GI research

Ongoing research in occupational health and environmental epidemiology in developing countries

DOE Office of Scientific and Technical Information (OSTI.GOV)

Levy, B.S.; Kjellstrom, T.; Forget, G.

Research in occupational health and environmental epidemiology can play an important role in furthering our understanding of occupational and environmental health problems. Research guides us in the recognition, management, and prevention of health problems. However, in developing countries, where rates of occupational and environmental illnesses and injuries are higher and where these problems are often more severe than in developed countries, research capabilities are less developed. In mid-1990, a project was undertaken to (a) document ongoing research in occupational health and environmental epidemiology in developing countries, (b) facilitate the exchange of information among researchers in this field, (c) stimulate research,more » and (d) avoid unnecessary duplication among researchers in this field. A questionnaire was mailed, the purpose of which was to learn the current status of research in developing countries and to develop a directory of such ongoing research. The questionnaire was sent to 1,528 individuals. Of the 500 research projects identified, 77% were investigating chemical hazards; 26%, physical hazards; 10%, biological hazards; 10%, psychosocial hazards (some projects addressed multiple hazards). The chemical hazards studied most frequently were dusts, pesticides, and lead. The greatest number of research projects were identified in China, India, Brazil, Korea, and Thailand. Most projects were descriptive or cross-sectional epidemiologic studies or industrial hygiene or exposure-assessment studies. The World Health Organization has published a directory of the specific research projects that were identified in this survey.« less

20171015 - Generating Exposure-Relevant Measurement Data for Potential Use in Support of TSCA Requirements (ISES)

EPA Science Inventory

The EPA Office of Research and Development (ORD) has a number of ongoing projects which generate exposure measurements. These data may inform ongoing implementation of the amended Toxic Substances Control Act (TSCA). Exposure measurements include physical-chemical property inform...

Ongoing Inquiry

ERIC Educational Resources Information Center

Ashbrook, Peggy

2011-01-01

An in-depth science inquiry is an ongoing investigation in which children are introduced to materials through hands-on experiences and, with teacher guidance, begin to investigate a question that they can answer through their own actions, observations, and with teacher-assisted research. Qualities that make an experience appropriate to include in…

Renewable energy projects in the Dominican Republic

DOE Office of Scientific and Technical Information (OSTI.GOV)

Viani, B.

1997-12-01

This paper describes a US/Dominican Republic program to develop renewable energy projects in the country. The objective is to demonstrate the commercial viability of renewable energy generation projects, primarily small-scale wind and hydropower. Preliminary studies are completed for three micro-hydro projects with a total capacity of 262 kWe, and two small wind power projects for water pumping. In addition wind resource assessment is ongoing, and professional training and technical assistance to potential investors is ongoing. Projects goals include not less than ten small firms actively involved in installation of such systems by September 1998.

The relationship between masking and short-term consolidation during recall from visual working memory.

PubMed

Ricker, Timothy J; Sandry, Joshua

2018-04-10

The presentation of a similar but irrelevant stimulus immediately following presentation of a memory item is called masking. Masking is known to reduce performance on working memory tests. This is the type of memory used to hold information in mind for brief periods of time for use in ongoing cognition. Two approaches to understanding masking effects have been proposed in different literatures. Working memory researchers often assume that the reduction in working memory performance after masking is because masking interferes with a transient sensory representation that is needed to complete consolidation into a working memory state. Researchers focused on the attentional blink, a finding that attention cannot be directed to new stimuli during working memory consolidation, have an alternative theory. Attentional blink researchers assume that masking slows the short-term consolidation process, thereby extending the length of the attentional blink. In two experiments, we contrast these two approaches to explaining masking effects and investigate the validity of both hypotheses. Some aspects of both approaches are validated, but neither theoretical perspective alone sufficiently explains the entire pattern of results. © 2018 New York Academy of Sciences.

Legionella and risk management in hospitals-A bibliographic research methodology for people responsible for built environment and facility management.

PubMed

Leiblein, Thomas W; Tucker, Matthew; Ashall, Mal; Lee, Susanne B; Gollnisch, Carsten; Hofer, Susanne

2016-11-01

An ongoing research project investigates the roles and duties of persons responsible for the built environment with respect to risk management of water systems and Legionella prevention from a facility management's perspective. Our literature review provides an approach for selecting and analysing abstracts of initially 177 journal articles, subjected to certain topic-specific inclusion and exclusion criteria. Different decision strategies of either logic 'yes/no', Boolean operators 'OR' or 'AND' and decisions for single counts or cumulative counts of the identified three principal keywords 'Legionella', 'hospital' and 'water', were completed. A final list of ten principal reference articles from 29 journals was compiled. It suggests that the interconnected perspective of water systems, Legionella and hospitals seems to be underrepresented in the field of the built environment and facility management. The term 'stakeholder', which would refer to decision-makers, was not found more than once. Our result is a useful summary of established sources of information on environmental Legionella research. The results can be helpful for those new to the topic. Copyright © 2016 Elsevier GmbH. All rights reserved.

Psychophysics of complex auditory and speech stimuli

NASA Astrophysics Data System (ADS)

Pastore, Richard E.

1993-10-01

A major focus on the primary project is the use of different procedures to provide converging evidence on the nature of perceptual spaces for speech categories. Completed research examined initial voiced consonants, with results providing strong evidence that different stimulus properties may cue a phoneme category in different vowel contexts. Thus, /b/ is cued by a rising second format (F2) with the vowel /a/, requiring both F2 and F3 to be rising with /i/, and is independent of the release burst for these vowels. Furthermore, cues for phonetic contrasts are not necessarily symmetric, and the strong dependence of prior speech research on classification procedures may have led to errors. Thus, the opposite (falling F2 and F3) transitions lead somewhat ambiguous percepts (i.e., not /b/) which may be labeled consistently (as /d/ or /g/), but requires a release burst to achieve high category quality and similarity to category exemplars. Ongoing research is examining cues in other vowel contexts and issuing procedures to evaluate the nature of interaction between cues for categories of both speech and music.

On the road to DSM-V and ICD-11.

PubMed

Kupfer, David J; Regier, Darrel A; Kuhl, Emily A

2008-11-01

Development of the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) has been ongoing since 1994, though official release will not occur for another 4 years. Potential revisions are being derived from multiple sources, including building on perceived limitations of DSM-IV; broad-based literature reviews; secondary and primary data analyses; and discussions between global members of the mental health community. The current focus on aligning DSM with the International Classification of Diseases-11 (ICD-11) speaks to the importance of creating a unified text that embraces cross-cutting issues of diagnostics, such as developmental, age-related, and cultural phenomena. International discourse is vital to this process and has been fostered by a National Institutes of Health-sponsored conference series on diagnosis-specific topics. From this series, the DSM-V Task Force developed the following set of revision principals to guide the efforts of the DSM-V Work Groups: grounding recommendations in empirical evidence; maintaining continuity with previous editions of DSM; removing a priori limitations on the amount of changes DSM-V may incur; and maintaining DSM's status as a living document. With work group formation complete, members are currently carrying out the research and revision recommendations proposed during the conference series. Ongoing activities include adding specialized advisors to each work group; completing literature reviews and planning data analyses; and forming study groups to discuss integration of cross-cutting issues (e.g., developmental lifespan factors; formation of diagnostic spectra). The road to DSM-V and ICD-11 has been challenging, but members continue to work diligently in their goal of constructing the most harmonious, scientifically sound, and clinically relevant DSM to date.

Resources for Teachers Starting a Planet Protector’s Club

EPA Pesticide Factsheets

EPA’s Planet Protector activities are a great way to get student’s interested in reducing, reusing and recycling. Use the activities to launch an ongoing club with our club factsheet, membership badge, activity calendar, and certificate of completion.

Origin of Outer Solar System

NASA Technical Reports Server (NTRS)

Holman, Matthew J.; Lindstrom, David (Technical Monitor)

2005-01-01

Our ongoing research program combines extensive deep and wide-field observations using a variety of observational platforms with numerical studies of the dynamics of small bodies in the outer solar system in order to advance the main scientific goals of the community studying the Kuiper belt and the outer solar system. These include: (1) determining the relative populations of the known classes of KBOs as well as other possible classes; ( 2 ) determining the size distributions or luminosity function of the individual populations or the Kuiper belt as a whole; (3) determining the inclinations distributions of these populations; (4) establishing the radial extent of the Kuiper belt; ( 5 ) measuring and relating the physical properties of different types of KBOs to those of other solar system bodies; and, (6) completing our systematic inventory of the satellites of the outer planets.

STRATEGIES AND TECHNOLOGY FOR MANAGING HIGH-CARBON ASH

DOE Office of Scientific and Technical Information (OSTI.GOV)

Robert Hurt; Eric Suuberg; John Veranth

2002-09-10

The overall objective of the present project is to identify and assess strategies and solutions for the management of industry problems related to carbon in ash. Specific research issues to be addressed include: (1) the effect of parent fuel selection on ash properties and adsorptivity, including a first ever examination of the air entrainment behavior of ashes from alternative (non-coal) fuels; (2) the effect of various low-NOx firing modes on ash properties and adsorptivity; and (3) the kinetics and mechanism of ash ozonation. This data will provide scientific and engineering support of the ongoing process development activities. During this fourthmore » project period we completed the characterization of ozone-treated carbon surfaces and wrote a comprehensive report on the mechanism through which ozone suppresses the adsorption of concrete surfactants.« less

Managing multicentre clinical trials with open source.

PubMed

Raptis, Dimitri Aristotle; Mettler, Tobias; Fischer, Michael Alexander; Patak, Michael; Lesurtel, Mickael; Eshmuminov, Dilmurodjon; de Rougemont, Olivier; Graf, Rolf; Clavien, Pierre-Alain; Breitenstein, Stefan

2014-03-01

Multicentre clinical trials are challenged by high administrative burden, data management pitfalls and costs. This leads to a reduced enthusiasm and commitment of the physicians involved and thus to a reluctance in conducting multicentre clinical trials. The purpose of this study was to develop a web-based open source platform to support a multi-centre clinical trial. We developed on Drupal, an open source software distributed under the terms of the General Public License, a web-based, multi-centre clinical trial management system with the design science research approach. This system was evaluated by user-testing and well supported several completed and on-going clinical trials and is available for free download. Open source clinical trial management systems are capable in supporting multi-centre clinical trials by enhancing efficiency, quality of data management and collaboration.

Fostering EMA's transparency policy.

PubMed

Banzi, Rita; Bertele', Vittorio; Demotes-Mainard, Jacques; Garattini, Silvio; Gluud, Christian; Kubiak, Christine; Ohmann, Christian

2014-10-01

The European Medicines Agency has opened a window to access clinical trial data. This is an important step forward which deserves attention, support, and advice from all the stakeholders. Regulatory agencies are the most comprehensive repositories of clinical trial data on drugs and can also promote and develop standard practices for data sharing. The release of the EMA draft policy on publication and access to clinical trial data in 2013 has fueled a lively debate among academia, industry, and the public in general that is still ongoing. As clinical researchers and producers and users of clinical trial data, we endorse the European Medicines Agency's opening and offer a few suggestions for complete, safe, and effective data sharing. Copyright © 2014 European Federation of Internal Medicine. Published by Elsevier B.V. All rights reserved.

The first genome sequences of human bocaviruses from Vietnam

PubMed Central

Thanh, Tran Tan; Van, Hoang Minh Tu; Hong, Nguyen Thi Thu; Nhu, Le Nguyen Truc; Anh, Nguyen To; Tuan, Ha Manh; Hien, Ho Van; Tuong, Nguyen Manh; Kien, Trinh Trung; Khanh, Truong Huu; Nhan, Le Nguyen Thanh; Hung, Nguyen Thanh; Chau, Nguyen Van Vinh; Thwaites, Guy; van Doorn, H. Rogier; Tan, Le Van

2017-01-01

As part of an ongoing effort to generate complete genome sequences of hand, foot and mouth disease-causing enteroviruses directly from clinical specimens, two complete coding sequences and two partial genomic sequences of human bocavirus 1 (n=3) and 2 (n=1) were co-amplified and sequenced, representing the first genome sequences of human bocaviruses from Vietnam. The sequences may aid future study aiming at understanding the evolution of the virus. PMID:28090592

Strategies to Increase After-School Program Staff Skills to Promote Healthy Eating and Physical Activity.

PubMed

Weaver, R Glenn; Beets, Michael W; Beighle, Aaron; Webster, Collin; Huberty, Jennifer; Moore, Justin B

2016-01-01

Standards targeting children's healthy eating and physical activity (HEPA) in after-school programs call for staff to display or refrain from HEPA-promoting or -discouraging behaviors that are linked to children's HEPA. This study evaluated strategies to align staff behaviors with HEPA Standards. Staff at four after-school programs serving approximately 500 children participated in professional development training from January 2012 to May 2013. Site leaders also attended workshops and received technical support during the same time frame. Changes in staff behaviors were evaluated using the System for Observing Staff Promotion of Activity and Nutrition in a pre- (fall 2011) multiple-post (spring 2012, fall 2012, and spring 2013), no-control group study design. A total of 8,949 scans were completed across the four measurement periods. Of the 19 behaviors measured, 14 changed in the appropriate direction. For example, staff engaging in physical activity with children increased from 27% to 40% of scans and staff eating unhealthy foods decreased from 56% to 14% of days. Ongoing training and technical assistance can have a measureable impact on staff behaviors linked to child-level HEPA outcomes. Future research should explore the feasibility of disseminating ongoing trainings to after-school program staff on a large scale. © 2015 Society for Public Health Education.

Wastewater treatment with submerged fixed bed biofilm reactor systems--design rules, operating experiences and ongoing developments.

PubMed

Schlegel, S; Koeser, H

2007-01-01

Wastewater treatment systems using bio-films that grow attached to a support media are an alternative to the widely used suspended growth activated sludge process. Different fixed growth biofilm reactors are commercially used for the treatment of municipal as well as industrial wastewater. In this paper a fairly new fixed growth biofilm system, the submerged fixed bed biofilm reactor (SFBBR), is discussed. SFBBRs are based on aerated submerged fixed open structured plastic media for the support of the biofilm. They are generally operated without sludge recirculation in order to avoid clogging of the support media and problems with the control of the biofilm. Reactor and process design considerations for these reactors are reviewed. Measures to ensure the development and maintenance of an active biofilm are examined. SFBBRs have been applied successfully to small wastewater treatment plants where complete nitrification but no high degree of denitrification is necessary. For the pre-treatment of industrial wastewater the use of SFBBRs is advantageous, especially in cases of wastewater with high organic loading or high content of compounds with low biodegradability. Performance data from exemplary commercial plants are given. Ongoing research and development efforts aim at achieving a high simultaneous total nitrogen (TN) removal of aerated SFBBRs and at improving the efficiency of TN removal in anoxic SFBBRs.

In-Cardiome: integrated knowledgebase for coronary artery disease enabling translational research

PubMed Central

Sharma, Ankit; Deshpande, Vrushali; Ghatge, Madankumar

2017-01-01

Abstract Coronary artery disease (CAD) is a leading cause of death worldwide. Prevention, diagnosis and clinical interventions are dependent on the conventional risk factors like hypertension, diabetes and obesity. However, these conventional risk factors do not completely identify high risk individuals. One major hurdle in the improvement of diagnosis and treatment for CAD is the lack of integration of knowledge from different areas of research like molecular, clinical and drug development. In order to provide comprehensive information from hitherto dispersed data, we developed an integrative knowledgebase called “In-Cardiome or Integrated Cardiome” for all the stake holders in healthcare such as scientists, clinicians and pharmaceutical companies. It is created by integrating 16 different data sources, 995 curated genes classified into 12 different functional categories associated with disease, 1204 completed clinical trials, 12 therapy or drug classifications with 62 approved drugs and drug target networks. This knowledgebase gives the most needed opportunity to understand the disease process and therapeutic impact along with gene expression data from both animal models and patients. The data is classified into three different search categories functional groups, risk factors and therapy/drug based classes. One more unique aspect of In-Cardiome is integration of clinical data of 10,217 subject data from our ongoing Indian Atherosclerosis Research Study (IARS) (6357 unaffected and 3860 CAD affected). IARS data showing demographics and associations of individual and combinations of risk factors in Indian population along with molecular information will enable better translational and drug development research. Database URL www.tri-incardiome.org PMID:29220465

Time course of ongoing activity during neuritis and following axonal transport disruption.

PubMed

Satkeviciute, Ieva; Goodwin, George; Bove, Geoffrey M; Dilley, Andrew

2018-05-01

Local nerve inflammation (neuritis) leads to ongoing activity and axonal mechanical sensitivity (AMS) along intact nociceptor axons and disrupts axonal transport. This phenomenon forms the most feasible cause of radiating pain, such as sciatica. We have previously shown that axonal transport disruption without inflammation or degeneration also leads to AMS but does not cause ongoing activity at the time point when AMS occurs, despite causing cutaneous hypersensitivity. However, there have been no systematic studies of ongoing activity during neuritis or noninflammatory axonal transport disruption. In this study, we present the time course of ongoing activity from primary sensory neurons following neuritis and vinblastine-induced axonal transport disruption. Whereas 24% of C/slow Aδ-fiber neurons had ongoing activity during neuritis, few (<10%) A- and C-fiber neurons showed ongoing activity 1-15 days following vinblastine treatment. In contrast, AMS increased transiently at the vinblastine treatment site, peaking on days 4-5 (28% of C/slow Aδ-fiber neurons) and resolved by day 15. Conduction velocities were slowed in all groups. In summary, the disruption of axonal transport without inflammation does not lead to ongoing activity in sensory neurons, including nociceptors, but does cause a rapid and transient development of AMS. Because it is proposed that AMS underlies mechanically induced radiating pain, and a transient disruption of axonal transport (as previously reported) leads to transient AMS, it follows that processes that disrupt axonal transport, such as neuritis, must persist to maintain AMS and the associated symptoms. NEW & NOTEWORTHY Many patients with radiating pain lack signs of nerve injury on clinical examination but may have neuritis, which disrupts axonal transport. We have shown that axonal transport disruption does not induce ongoing activity in primary sensory neurons but does cause transient axonal mechanical sensitivity. The present data complete a profile of key axonal sensitivities following axonal transport disruption. Collectively, this profile supports that an active peripheral process is necessary for maintained axonal sensitivities.

Exposure Modeling Tools and Databases for Consideration for Relevance to the Amended TSCA (ISES)

EPA Science Inventory

The Agency’s Office of Research and Development (ORD) has a number of ongoing exposure modeling tools and databases. These efforts are anticipated to be useful in supporting ongoing implementation of the amended Toxic Substances Control Act (TSCA). Under ORD’s Chemic...

Benefits of the NADE Certification Process: Self-Knowledge, Informed Choices & Programmatic Strength

ERIC Educational Resources Information Center

Greci, Dana

2016-01-01

Research shows that systematic, ongoing program evaluation is needed to adequately assess the effectiveness of developmental programs. Ongoing evaluation provides both (1) validation of programs to educational institutions and legislators; and (2) impetus for program improvement. The author of this article works in the Developmental Education…

An Ongoing Investigation of Science Literacy: Results of a 22-Year Study Probing Students' Knowledge and Attitude Towards Science

NASA Astrophysics Data System (ADS)

Impey, C.; Buxner, S.; Antonellis, J.; CATS

2013-04-01

This talk presents findings related to our ongoing work investigating students' knowledge and attitudes towards science and technology. We present an overview of research studies and findings including a comparison of the science literacy measures of University of Arizona students compared to national studies, conceptions related to astrology, views of radiation, and students' pseudoscience and religious beliefs. We discuss implications for instructors and researchers interested in improving students' science literacy scores and diagnosing alternative beliefs.

Towards Improving our Understanding on the Retrievals of Key Parameters Characterising Land Surface Interactions from Space: Introduction & First Results from the PREMIER-EO Project

NASA Astrophysics Data System (ADS)

Ireland, Gareth; North, Matthew R.; Petropoulos, George P.; Srivastava, Prashant K.; Hodges, Crona

2015-04-01

Acquiring accurate information on the spatio-temporal variability of soil moisture content (SM) and evapotranspiration (ET) is of key importance to extend our understanding of the Earth system's physical processes, and is also required in a wide range of multi-disciplinary research studies and applications. The utility and applicability of Earth Observation (EO) technology provides an economically feasible solution to derive continuous spatio-temporal estimates of key parameters characterising land surface interactions, including ET as well as SM. Such information is of key value to practitioners, decision makers and scientists alike. The PREMIER-EO project recently funded by High Performance Computing Wales (HPCW) is a research initiative directed towards the development of a better understanding of EO technology's present ability to derive operational estimations of surface fluxes and SM. Moreover, the project aims at addressing knowledge gaps related to the operational estimation of such parameters, and thus contribute towards current ongoing global efforts towards enhancing the accuracy of those products. In this presentation we introduce the PREMIER-EO project, providing a detailed overview of the research aims and objectives for the 1 year duration of the project's implementation. Subsequently, we make available the initial results of the work carried out herein, in particular, related to an all-inclusive and robust evaluation of the accuracy of existing operational products of ET and SM from different ecosystems globally. The research outcomes of this project, once completed, will provide an important contribution towards addressing the knowledge gaps related to the operational estimation of ET and SM. This project results will also support efforts ongoing globally towards the operational development of related products using technologically advanced EO instruments which were launched recently or planned be launched in the next 1-2 years. Key Words: PREMIER-EO, HPC Wales, Soil Moisture, Evapotranspiration, , Earth Observation

Exposure to acute stress is associated with attenuated sweet taste.

PubMed

Al'Absi, Mustafa; Nakajima, Motohiro; Hooker, Stephanie; Wittmers, Larry; Cragin, Tiffany

2012-01-01

This study examined the effects of stress on taste perception. Participants (N = 38; 21 women) completed two laboratory sessions: one stress (public speaking, math, and cold pressor) and one control rest session. The taste perception test was conducted at the end of each session and included rating the intensity and pleasantness of sweet, salty, sour, and savory solutions at suprathreshold concentrations. Cardiovascular, hormonal, and mood measures were collected throughout the sessions. Participants showed the expected changes in cardiovascular, hormonal, and mood measures in response to stress. Reported intensity of the sweet solution was significantly lower on the stress day than on the rest day. Cortisol level poststress predicted reduced intensity of salt and sour, suggesting that stress-related changes in adrenocortical activity were related to reduced taste intensity. Results indicate that acute stress may alter taste perception, and ongoing research investigates the extent to which these changes mediate effects of stress on appetite. Copyright © 2011 Society for Psychophysiological Research.

Psychometric properties of the Compulsive Exercise Test in an adolescent eating disorder population.

PubMed

Formby, Pam; Watson, Hunna J; Hilyard, Anna; Martin, Kate; Egan, Sarah J

2014-12-01

The objective of this study was to evaluate the factor structure, validity, and reliability of the Compulsive Exercise Test (CET) in an adolescent clinical eating disorder population. The data source was the Helping to Outline Paediatric Eating Disorders (HOPE) Project, a prospective ongoing registry study comprising consecutive pediatric tertiary eating disorder referrals. Adolescents (N=104; 12-17years) with eating disorders completed the CET and other measures. Factor structure, convergent validity, and internal consistency were evaluated. Despite failing to identify a factor structure, the study provided clear evidence of the multidimensionality of the measure. The total score correlated significantly with measures of eating pathology, perfectionism, and frequency of exercise for shape and weight control (r=0.32-0.70, ps<0.05). More research into the multidimensional nature of compulsive exercise in clinical populations is needed. Further, research into compulsive exercise offers promise as an addition to existing cognitive behavioral models and treatments for eating disorders. Copyright © 2014 Elsevier Ltd. All rights reserved.

Providing information regarding exposures in pregnancy: a survey of North American Teratology Information Services.

PubMed

Hancock, Rebecca L; Ungar, Wendy J; Einarson, Adrienne; Goodstadt, Michael; Koren, Gideon

2008-04-01

Teratology Information Services (TIS) provide information on exposures during pregnancy and breast-feeding. Maintaining ongoing funding is a challenge. The purpose was to gather descriptive information on current TIS operations. All North American TIS (16 American, 2 Canadian) completed a detailed survey. Service goal ranked as most important was correction of risk misperceptions. Inquiries were primarily for medications (mean 43.5%, S.D. 14.1), lactation exposures, and workplace exposures. Median employees per TIS: three (range 1-12.5). Two TIS only counsel health care professionals (HCPs). Main callers to remaining TIS were pregnant women (mean 46.8%, S.D. 22.8), physicians, and nurses. Calls per week varied (median 20, range 4-600). Median annual budget: US dollars 69,000 (range dollars 3000-335,000). Seventeen TIS collect patient data for research. This survey was the first to document TIS operations in North America and demonstrates a spectrum of clinical and research activities, and provides data for a future cost-benefit analysis of TIS.

The Role of Diet in Inflammatory Bowel Disease.

PubMed

Shivashankar, Raina; Lewis, James D

2017-05-01

Diet may play both a causal and therapeutic role for inflammatory bowel disease (IBD). Physicians caring for patients with IBD are often asked to make dietary recommendations. However, there are no well-established guidelines on the use of diet as a treatment of IBD. In this review, we describe the evidence supporting diet as a potential cause for IBD, patient-perceived symptoms based on diet, current research on various diets as a treatment for IBD, and areas of future research. New studies in murine models suggest that dietary emulsifiers may trigger the gut inflammatory cascade. New studies of restriction diets in patients have shown a relationship between dietary intake, symptoms, and bowel inflammation. Until several ongoing clinical trials are completed, a reasonable approach to dietary recommendations for patients with IBD is to propose a well-balanced, healthy (low-fat, low-sugar) diet prepared from fresh ingredients, such as the Mediterranean diet, with exclusions of self-identified foods that worsen or trigger IBD-related symptoms.

The International Space Station: Stepping-stone to Exploration

NASA Technical Reports Server (NTRS)

Gerstenmaier, William H.; Kelly, Brian K.; Kelly, Brian K.

2005-01-01

As the Space Shuttle returns to flight this year, major reconfiguration and assembly of the International Space Station continues as the United States and our 5 International Partners resume building and carry on operating this impressive Earth-orbiting research facility. In his January 14, 2004, speech announcing a new vision for America's space program, President Bush ratified the United States' commitment to completing construction of the ISS by 2010. The current ongoing research aboard the Station on the long-term effects of space travel on human physiology will greatly benefit human crews to venture through the vast voids of space for months at a time. The continual operation of ISS leads to new knowledge about the design, development and operation of system and hardware that will be utilized in the development of new deep-space vehicles needed to fulfill the Vision for Exploration. This paper will provide an overview of the ISS Program, including a review of the events of the past year, as well as plans for next year and the future.

The evolution of withdrawal: negotiating research relationships in biobanking.

PubMed

Melham, Karen; Moraia, Linda Briceno; Mitchell, Colin; Morrison, Michael; Teare, Harriet; Kaye, Jane

2014-01-01

The right to withdraw from research, along with the necessity of adequately informed consent, is at the heart of the post-Nuremburg code of ethical safeguards in biomedical research on human participants. As biomedical research moves away from direct interventional studies towards research using networks of linked human tissue samples and data, however, questions arise about what withdrawal can and should mean in these new contexts. Some of the more expansive traditional understandings, such as the right to withdraw from a study 'at any time' are limited in practice by the nature of biobank- supported research, particularly where it makes possible widespread dissemination and ongoing reuse of data. It is time for a more nuanced, granular arrangement for withdrawal, appropriate to the ongoing relationships between participants and long-term biobanking enterprises.

The practise and practice of Bourdieu: the application of social theory to youth alcohol research.

PubMed

Lunnay, Belinda; Ward, Paul; Borlagdan, Joseph

2011-11-01

Some years ago Australian anthropologist David Moore criticised the predominant form of understanding youth alcohol consumption for residing with biomedical approaches that individualise and ultimately stigmatise drinking behaviour and 'ignore' the social context of consumption. Of interest here is the ongoing insufficient integration of alternative approaches to understanding young people's drinking. This paper presents theoretically informed qualitative research that investigates why young Australian females (aged 14-17) drink and how social and cultural context form the basis, rather than the periphery, of their drinking experience. We demonstrate the utility of Pierre Bourdieu's sociological framework for delving beyond the dichotomy of young people's drinking decisions as either a determination of their cultural environment or the singular result of a rational individual's independent decision-making. The paper is presented in two parts. First, we provide the interpretation, or 'practise', of Bourdieu's concepts through an outline and application of his complex theoretical constructs. Specifically, the concept of symbolic capital (or social power) is applied. Second, our explication of Bourdieu's 'practice', or epistemological contributions, offers a methodologically grounded example to other researchers seeking to attain more complete understandings of the social processes underpinning youth alcohol consumption. A sociological approach to exploring the complex relationship between drinking and contextual social factors amongst young Australian females is an unchartered area of enquiry. We contribute new theoretically supported insights to create a more complete picture of young females' drinking behaviours. Crown Copyright © 2011. Published by Elsevier B.V. All rights reserved.

Characteristics and follow-up of postmarketing studies of conditionally authorized medicines in the EU.

PubMed

Hoekman, Jarno; Klamer, Thea T; Mantel-Teeuwisse, Aukje K; Leufkens, Hubert G M; De Bruin, Marie L

2016-07-01

The aim of the present study was to provide an insight into the characteristics and follow-up of postmarketing studies of medicines that were conditionally authorized in the European Union (EU). We compiled a list of all postmarketing studies attached as specific obligations to the licence of medicines that were granted conditional marketing authorization from January 2006 to April 2014. Studies were characterized based on their objective, design, status upon marketing authorization (MA) and due data set by authorities. They were linked to online study registrations (Clinicaltrials.gov, ENCePP) to determine completion date. We described and associated characteristics of studies and medicines, and determined whether studies were completed on time. A total of 59 postmarketing studies were requested for 21 conditionally authorized medicines. Most studies had an interventional study design (73%), were ongoing upon MA (61%) and aimed to provide additional data on efficacy (45%). Interventional studies were more often ongoing and providing efficacy data, while observational and other studies were more often new and providing safety data. Frequent grounds for requesting postmarketing studies were 'long-term follow-up' and 'increase data on subpopulations'. Of the 34 studies eligible for follow-up analysis, 26 (76%) were completed and 17 (50%) completed on time. Actual completion time took a median (interquartile range) of 274 (-121 to 556) days longer than expected. Our results indicated that most postmarketing studies attached to a conditional marketing authorization were eventually completed but that half were completed with a substantial delay. The observations suggest caution when broadening the use of postmarketing studies for resolving uncertainties about benefits and risks after MA. © 2016 The British Pharmacological Society.

Characteristics and follow‐up of postmarketing studies of conditionally authorized medicines in the EU

PubMed Central

Klamer, Thea T.; Mantel‐Teeuwisse, Aukje K.; Leufkens, Hubert G. M.; De Bruin, Marie L.

2016-01-01

Aim The aim of the present study was to provide an insight into the characteristics and follow‐up of postmarketing studies of medicines that were conditionally authorized in the European Union (EU). Methods We compiled a list of all postmarketing studies attached as specific obligations to the licence of medicines that were granted conditional marketing authorization from January 2006 to April 2014. Studies were characterized based on their objective, design, status upon marketing authorization (MA) and due data set by authorities. They were linked to online study registrations (Clinicaltrials.gov, ENCePP) to determine completion date. We described and associated characteristics of studies and medicines, and determined whether studies were completed on time. Results A total of 59 postmarketing studies were requested for 21 conditionally authorized medicines. Most studies had an interventional study design (73%), were ongoing upon MA (61%) and aimed to provide additional data on efficacy (45%). Interventional studies were more often ongoing and providing efficacy data, while observational and other studies were more often new and providing safety data. Frequent grounds for requesting postmarketing studies were ‘long‐term follow‐up’ and ‘increase data on subpopulations’. Of the 34 studies eligible for follow‐up analysis, 26 (76%) were completed and 17 (50%) completed on time. Actual completion time took a median (interquartile range) of 274 (−121 to 556) days longer than expected. Conclusions Our results indicated that most postmarketing studies attached to a conditional marketing authorization were eventually completed but that half were completed with a substantial delay. The observations suggest caution when broadening the use of postmarketing studies for resolving uncertainties about benefits and risks after MA. PMID:26992001

The Soreq Applied Research Accelerator Facility (SARAF): Overview, research programs and future plans

NASA Astrophysics Data System (ADS)

Mardor, Israel; Aviv, Ofer; Avrigeanu, Marilena; Berkovits, Dan; Dahan, Adi; Dickel, Timo; Eliyahu, Ilan; Gai, Moshe; Gavish-Segev, Inbal; Halfon, Shlomi; Hass, Michael; Hirsh, Tsviki; Kaiser, Boaz; Kijel, Daniel; Kreisel, Arik; Mishnayot, Yonatan; Mukul, Ish; Ohayon, Ben; Paul, Michael; Perry, Amichay; Rahangdale, Hitesh; Rodnizki, Jacob; Ron, Guy; Sasson-Zukran, Revital; Shor, Asher; Silverman, Ido; Tessler, Moshe; Vaintraub, Sergey; Weissman, Leo

2018-05-01

The Soreq Applied Research Accelerator Facility (SARAF) is under construction in the Soreq Nuclear Research Center at Yavne, Israel. When completed at the beginning of the next decade, SARAF will be a user facility for basic and applied nuclear physics, based on a 40 MeV, 5 mA CW proton/deuteron superconducting linear accelerator. Phase I of SARAF (SARAF-I, 4 MeV, 2 mA CW protons, 5 MeV 1 mA CW deuterons) is already in operation, generating scientific results in several fields of interest. The main ongoing program at SARAF-I is the production of 30 keV neutrons and measurement of Maxwellian Averaged Cross Sections (MACS), important for the astrophysical s-process. The world leading Maxwellian epithermal neutron yield at SARAF-I (5 × 10^{10} epithermal neutrons/s), generated by a novel Liquid-Lithium Target (LiLiT), enables improved precision of known MACSs, and new measurements of low-abundance and radioactive isotopes. Research plans for SARAF-II span several disciplines: precision studies of beyond-Standard-Model effects by trapping light exotic radioisotopes, such as 6He, 8Li and 18, 19, 23Ne, in unprecedented amounts (including meaningful studies already at SARAF-I); extended nuclear astrophysics research with higher energy neutrons, including generation and studies of exotic neutron-rich isotopes relevant to the rapid (r-) process; nuclear structure of exotic isotopes; high energy neutron cross sections for basic nuclear physics and material science research, including neutron induced radiation damage; neutron based imaging and therapy; and novel radiopharmaceuticals development and production. In this paper we present a technical overview of SARAF-I and II, including a description of the accelerator and its irradiation targets; a survey of existing research programs at SARAF-I; and the research potential at the completed facility (SARAF-II).

DOE Office of Scientific and Technical Information (OSTI.GOV)

Looney, B; Dawn S. Kaback, D; Eugene L. LeBoeuf, E

Beginning in 2006, the US Department of Energy (DOE) supported nine applied research projects to improve the protection of the Columbia River and mitigate the impacts of Hanford Site groundwater. These projects were funded through a supplemental Congressional budget allocation, and are now in various stages of completion in accordance with the research plans. The DOE Office of Environmental Management Groundwater and Soil Cleanup Technologies (EM-22) sponsored a technical peer review meeting for these projects in Richland WA, July 28-31, 2008. The overall objective of the peer review is to provide information to support DOE decisions about the status andmore » potential future application of the various technologies. The charge for the peer review panel was to develop recommendations for each of the nine 'technologies'. Team members for the July 2008 review were Brian Looney, Gene LeBoeuf, Dawn Kaback, Karen Skubal, Joe Rossabi, Paul Deutsch, and David Cocke. Previous project reviews were held in May 2007 and March-May of 2006. The team used the following four rating categories for projects: (a) Incorporate the technology/strategy in ongoing and future EM activities; (b) Finish existing scope of applied research and determine potential for EM activities when research program is finished; (c) Discontinue current development activities and do not incorporate technology/strategy into ongoing and future EM activities unless a significant and compelling change in potential viability is documented; and (d) Supplement original funded work to obtain the data needed to support a DOE decision to incorporate the technology into ongoing and future EM activities. The supplemental funding portfolio included two projects that addressed strontium, five projects that addressed chromium, one project that addressed uranium and one project that addressed carbon tetrachloride. The projects ranged from in situ treatment methods for immobilizing contaminants using chemical-based methods such as phosphate addition, to innovative surface treatment technologies such as electrocoagulation. Total funding for the nine projects was $9,900,000 in fiscal year (FY) 2006 and $2,000,000 in FY 2007. At the Richland meeting, the peer reviewers provided a generally neutral assessment of the projects and overall progress, and a generally positive assessment with regard to the principal investigators meeting their stated research objectives and performing the planned laboratory research and limited field work. Only one project, the Electrocoagulation Treatability Test, received a rating of 'discontinue' from the team because the project goals had not been met. Because this particular project has already ended, no action with respect to funding withdrawal is necessary. All other projects were recommended to be finished and/or incorporated into field efforts at Hanford. Specific technical comments and recommendations were provided by the team for each project.« less

Ongoing Voluntary Settlement and Independent Agency: Evidence from China

PubMed Central

Feng, Jing; Ren, Xiaopeng; Ma, Xinran

2017-01-01

Voluntary frontier settlement leads to independent agency. Since this type of research has not yet been implemented in ongoing voluntary settlement frontiers, we conducted several cultural tasks to investigate Shenzhen, known as China’s ongoing “South Frontier,” which is composed mostly of people that have emigrated from other Chinese provinces within the past 30 years. We hypothesized that residents of Shenzhen are more independent than those in other regions of Mainland China. As predicted, residents of Shenzhen scored higher than China inland residents in self-reported independent beliefs and scored lower in nepotism. The results indicate that, even in a short-term ongoing frontier, voluntary settlement is associated with independent agency. PMID:28798712

Credentialing Public Health Nurses: Current Issues and Next Steps Forward.

PubMed

Vandenhouten, Christine L; DeVance-Wilson, Crystal L; Little, Barbara Battin

2015-01-01

The purpose of this descriptive, cross-sectional study was to identify Public Health Nurses' (PHN) perceived motivators and barriers to seeking PHN board certification. In collaboration with the Quad Council of Public Health Nursing Organizations, PHNs from across the United States were invited to complete the PHN Certification Survey, a 14-item online questionnaire. A total of 912 surveys were completed. PHNs were motivated to seek PHN board certification by three overarching categories: professional competence, personal satisfaction, and financial incentives. Frequently cited barriers to certification were lack of knowledge of certification opportunities, being unaware of eligibility criteria, cost, perceived lack of value/reward by employer, and preparation time. Demonstrating a highly educated, competent, and reliable PHN workforce can only be achieved through ongoing professional development and credentialing. PH stakeholders (i.e., PHN organizations, employers, PHNs, etc.) need a strategic approach to address the main barriers to certification identified in this study (a) awareness of certification and eligibility criteria, and (b) recognition of the credential by employers. In addition, research on the relationship between PHN credentialing and population health outcomes is essential. © 2015 Wiley Periodicals, Inc.

Is the large simple trial design used for comparative, post-approval safety research? A review of a clinical trials registry and the published literature.

PubMed

Reynolds, Robert F; Lem, Joanna A; Gatto, Nicolle M; Eng, Sybil M

2011-10-01

Post-approval, observational drug safety studies face well known difficulties in controlling for confounding, particularly confounding by indication for drug use. A study design that addresses confounding by indication is the large simple trial (LST). LSTs are characterized by large sample sizes, often in the thousands; broad entry criteria consistent with the approved medication label; randomization based on equipoise, i.e. neither physician nor patient believes that one treatment option is superior; minimal, streamlined data collection requirements; objectively-measured endpoints (e.g. death, hospitalization); and follow-up that minimizes interventions or interference with normal clinical practice. In theory then, the LST is a preferred study design for drug and vaccine safety research because it controls for biases inherent to observational research while still providing results that are generalizable to 'real-world' use. To evaluate whether LSTs are used for comparative safety evaluation and if the design is, in fact, advantageous compared with other designs, we conducted a review of the published literature (1949 through 31 December 2010) and the ClinicalTrials.gov registry (2000 through 31 December 2010). Thirteen ongoing or completed safety LSTs were identified. The design has rarely been used in comparative drug safety research, which is due to the operational, financial and scientific hurdles of implementing the design. The studies that have been completed addressed important clinical questions and, in some cases, led to re-evaluation of medical practice. We conclude the design has demonstrated utility for comparative safety research of medicines and vaccines if the necessary scientific and operational conditions for its use are met.

ECOREGION DELINEATION IN TEXAS

EPA Science Inventory

Level III ecoregions are being refined and subdivided into level IV for the state of Texas. This work is consistent with ecoregion revision and subdivision that has been completed or is on-going in 37 of the conterminous United States. The two-year project is collaborative, inv...

Automated Methodologies for the Design of Flow Diagrams for Development and Maintenance Activities

NASA Astrophysics Data System (ADS)

Shivanand M., Handigund; Shweta, Bhat

The Software Requirements Specification (SRS) of the organization is a text document prepared by strategic management incorporating the requirements of the organization. These requirements of ongoing business/ project development process involve the software tools, the hardware devices, the manual procedures, the application programs and the communication commands. These components are appropriately ordered for achieving the mission of the concerned process both in the project development and the ongoing business processes, in different flow diagrams viz. activity chart, workflow diagram, activity diagram, component diagram and deployment diagram. This paper proposes two generic, automatic methodologies for the design of various flow diagrams of (i) project development activities, (ii) ongoing business process. The methodologies also resolve the ensuing deadlocks in the flow diagrams and determine the critical paths for the activity chart. Though both methodologies are independent, each complements other in authenticating its correctness and completeness.

A New U.S. Carbon Cycle Science Plan

NASA Astrophysics Data System (ADS)

Michalak, A. M.; Jackson, R.; Marland, G.; Sabine, C.

2009-05-01

The report "A U.S. carbon cycle science plan" (J. L. Sarmiento and S. C. Wofsy, U.S. Global Change Res. Program, Washington, D. C., 1999) outlined research priorities and promoted coordinated carbon cycle research across federal agencies in the United States for nearly a decade. Building on this framework and subsequent reports (http://www.carboncyclescience.gov/docs.php), a working group comprised of 27 scientists was formed in 2008 under the United States Carbon Cycle Science Program to review the 1999 Science Plan, and to develop an updated strategy for carbon cycle research for the period from 2010 to 2020. This comprehensive review is being conducted with wide input from the research and stakeholder communities. The recommendations of the Carbon Cycle Science Working Group (CCSWG) will go to U.S. agency managers who have collective responsibility for setting national carbon cycle science priorities and for sponsoring much of the carbon cycle research in the United States. This presentation will provide an update on the ongoing planning process, will outline the steps that the CCSWG is undertaking in building consensus towards an updated U.S. Carbon Cycle Science Plan, and will seek input on the best ways in which to coordinate efforts with ongoing and upcoming research in Canada and Mexico, as well as with ongoing work globally.

A Distributed Web-based Solution for Ionospheric Model Real-time Management, Monitoring, and Short-term Prediction

NASA Astrophysics Data System (ADS)

Kulchitsky, A.; Maurits, S.; Watkins, B.

2006-12-01

With the widespread availability of the Internet today, many people can monitor various scientific research activities. It is important to accommodate this interest providing on-line access to dynamic and illustrative Web-resources, which could demonstrate different aspects of ongoing research. It is especially important to explain and these research activities for high school and undergraduate students, thereby providing more information for making decisions concerning their future studies. Such Web resources are also important to clarify scientific research for the general public, in order to achieve better awareness of research progress in various fields. Particularly rewarding is dissemination of information about ongoing projects within Universities and research centers to their local communities. The benefits of this type of scientific outreach are mutual, since development of Web-based automatic systems is prerequisite for many research projects targeting real-time monitoring and/or modeling of natural conditions. Continuous operation of such systems provide ongoing research opportunities for the statistically massive validation of the models, as well. We have developed a Web-based system to run the University of Alaska Fairbanks Polar Ionospheric Model in real-time. This model makes use of networking and computational resources at the Arctic Region Supercomputing Center. This system was designed to be portable among various operating systems and computational resources. Its components can be installed across different computers, separating Web servers and computational engines. The core of the system is a Real-Time Management module (RMM) written Python, which facilitates interactions of remote input data transfers, the ionospheric model runs, MySQL database filling, and PHP scripts for the Web-page preparations. The RMM downloads current geophysical inputs as soon as they become available at different on-line depositories. This information is processed to provide inputs for the next ionospheic model time step and then stored in a MySQL database as the first part of the time-specific record. The RMM then performs synchronization of the input times with the current model time, prepares a decision on initialization for the next model time step, and monitors its execution. Then, as soon as the model completes computations for the next time step, RMM visualizes the current model output into various short-term (about 1-2 hours) forecasting products and compares prior results with available ionospheric measurements. The RMM places prepared images into the MySQL database, which can be located on a different computer node, and then proceeds to the next time interval continuing the time-loop. The upper-level interface of this real-time system is the a PHP-based Web site (http://www.arsc.edu/SpaceWeather/new). This site provides general information about the Earth polar and adjacent mid-latitude ionosphere, allows for monitoring of the current developments and short-term forecasts, and facilitates access to the comparisons archive stored in the database.

EPA Office of Research and Development Green Infrastructure Research

EPA Science Inventory

This presentation provides an overview introduction to the USEPA Office of Research and Development (ORD)'s ongoing green infrastructure (GI) research efforts for stormwater management. GI approaches that increase infiltration, evapotranspiration, and rainwater harvesting offer ...

Willingness to complete advance directives among low-income older adults living in the USA.

PubMed

Ko, Eunjeong; Lee, Jaehoon; Hong, Youngjoon

2016-11-01

This study explored low-income older adults' willingness to (i) complete advance directives, legal documents, whereby an individual designates decision-makers in the event that they cannot make their own decisions about end-of-life treatment preferences, and (ii) the role of social support and other predictors that impact their willingness. This study was conducted as part of a larger study exploring behaviours of advance care planning among low-income older adults. Out of a total of 255 participants from the original study, this study included 204 participants who did not complete an advance directive for data analysis. A cross-sectional study using probability random sampling stratified by ethnicity was used. Older adults residing in two supportive housing facilities or who were members of a senior centre in San Diego, California, USA, were interviewed in person between December 2010 and April 2011. Hierarchical logistic regression analysis revealed that the majority of participants (72.1%) were willing to complete advance directives and the factors significantly predicting willingness to complete included self-rated health, attitudes towards advance decision-making and social support. Participants with a poorer health status (OR = 1.43, 95% CI = 1.07-1.90) were more willing to complete advance directives. Conversely, participants with higher positive attitudes (OR = 1.18, 95% CI = 1.00-1.39) and greater social support (OR = 1.07, 95% CI = 1.00-1.15) were also more willing to complete advance directives. The findings suggest the importance of ongoing support from healthcare professionals in end-of-life care planning. Healthcare professionals can be a source of support assisting older adults in planning end-of-life care. Initiating ongoing communication regarding personal value and preference for end-of-life care, providing relevant information and evaluating willingness to complete as well as assisting in the actual completion of advance directives will be necessary. © 2015 John Wiley & Sons Ltd.

Undergraduates Conducting Research Using High-Resolution Multibeam and Sidescan Sonar to Map and Characterize the Seabed: the BEAMS Program

NASA Astrophysics Data System (ADS)

Harris, M. S.; Sautter, L.

2017-12-01

The College of Charleston's BEnthic Acoustic Mapping and Survey (BEAMS) Program has just completed its 10th year of operation, and has proven to be remarkably effective at activating and maintaining undergraduate student interest in conducting research using sophisticated software, state-of-the-art instrumentation, enormous datasets, and significant experiential time. BEAMS students conduct research as part of a minimum 3-course sequence of marine geology-based content, marine geospatial software, and seafloor research courses. Over 140 students have completed the program, 56% of the graduated students remain active in the marine geospatial workforce or academic arenas. Forty-eight percent (48%) of those students are female. As undergraduates, students not only conduct independent research projects, but present their work at national conferences each year. Additionally, over 90 % of all "BEAMers" have been provided a 2-3 day at-sea experience on a dedicated BEAMS Program multibeam survey research cruise, and many students also volunteer as survey technicians aboard NOAA research vessels. Critical partnerships have developed with private industry to provide numerous collaborative opportunities and an employment/employer pipeline, as well as provision of software and hardware at many fiscal levels. Ongoing collaboration with the Marine Institute of Ireland and the National and Kapodistrian University of Athens has also provided valuable field opportunities and collaborative experiences. This talk will summarize the program while highlighting some of the key areas and topics investigated by students, including detailed geomorphologic studies of continental margins, submarine canyons, tectonic features and seamounts. Students also work with NOAA investigators to aid in the characterization of fish and deep coral habitats, and with BOEM researchers to study offshore windfield suitability and submerged cultural landscapes. Our sister program at the University of Washington will also be discussed, as will developing relationships with our international and private industry partners.

Rural youth violence: it is a public health concern!

PubMed

Kulig, Judith C; Nahachewsky, Deana; Hall, Barry L; Kalischuk, Ruth Grant

2005-01-01

Youth violence is a significant issue for public health because of the potential for long-term impacts on individuals, families and communities. Limited exposure to violence is seen as a component of healthy living. However, there is limited understanding of violence from a public health perspective within rural communities. Rural refers to those communities with a population less than 10,000 outside the main commuting zone of a large urban area. Population health approaches, including the social determinants of health, are well supported by public health officials. Generating information about rural youth violence from a Canadian perspective would add to our understanding of these social determinants while providing guidance for policy and program development. Current understandings of youth violence are limited to an urban, and oftentimes, American perspective. An ongoing two-phase Canadian study on rural youth violence included qualitative interviews with 52 youth and the completion of a questionnaire that had been developed from the qualitative responses. The questionnaire has been completed by a larger sample of rural youth. The findings generated from this ongoing study will be useful in linking violence with social factors that impact health and thereby guide population health programs and policies. In this way, the role of public health to develop policies and implement programs will be directly influenced by evidence while addressing an ongoing public health concern.

State of the art evaluation of traffic detection and monitoring systems. Volume 1, phases A & B : design [Summary

DOT National Transportation Integrated Search

2007-10-01

Accurate, complete, and timely traffic data is critical to the effective management of Arizonas highway system. Limitations in current traffic monitoring abilities are an ongoing challenge for the Arizona Department of Transportation (ADOT) and fo...

Indexing NASA programs for technology transfer methods development and feasibility

NASA Technical Reports Server (NTRS)

Clingman, W. H.

1972-01-01

This project was undertaken to evaluate the application of a previously developed indexing methodology to ongoing NASA programs. These programs are comprehended by the NASA Program Approval Documents (PADS). Each PAD contains a technical plan for the area it covers. It was proposed that these could be used to generate an index to the complete NASA program. To test this hypothesis two PADS were selected by the NASA Technology Utilization Office for trial indexing. Twenty-five individuals indexed the two PADS using NASA Thesaurus terms. The results demonstrated the feasibility of indexing ongoing NASA programs using PADS as the source of information. The same indexing methodology could be applied to other documents containing a brief description of the technical plan. Results of this project showed that over 85% of the concepts in the technology should be covered by the indexing. Also over 85% of the descriptors chosen would be accurate. This completeness and accuracy for the indexing is considered satisfactory for application in technology transfer.

Ongoing Recovery Basic Information Tool (ORBIT)

NASA Technical Reports Server (NTRS)

Oberg, Donald

1993-01-01

The Federal Drug Free Work Place Program (DFWP) has now matured to the point of being able to return employees to sensitive testing designated positions (TDP) after completion of treatment of their addiction. The known tendency of addicted individuals to suffer multiple relapses prior to their final recovery has resulted in several positive urine tests (relapses) occurring among those Federal employees who have already completed treatment and who have been returned to TDP's. The very real potential for further relapses occurring after additional employees return to TDP's will be a critical factor in the ultimate success of the DFWP and in the public's impression of the program's effectiveness. In response to this concern, NASA has begun development of its Ongoing Recovery Basic Information Tool (ORBIT) instrument. The aim of the NASA ORBIT is to provide Employee Assistance Program (EAP) professionals with an advanced clinical tool which will be helpful in supporting recovery from substance abuse and which will allow more accurate determinations of when clients may be successfully returned to sensitive positions.

Focus on cumulative emissions, global carbon budgets and the implications for climate mitigation targets

NASA Astrophysics Data System (ADS)

Damon Matthews, H.; Zickfeld, Kirsten; Knutti, Reto; Allen, Myles R.

2018-01-01

The Environmental Research Letters focus issue on ‘Cumulative Emissions, Global Carbon Budgets and the Implications for Climate Mitigation Targets’ was launched in 2015 to highlight the emerging science of the climate response to cumulative emissions, and how this can inform efforts to decrease emissions fast enough to avoid dangerous climate impacts. The 22 research articles published represent a fantastic snapshot of the state-or-the-art in this field, covering both the science and policy aspects of cumulative emissions and carbon budget research. In this Review and Synthesis, we summarize the findings published in this focus issue, outline some suggestions for ongoing research needs, and present our assessment of the implications of this research for ongoing efforts to meet the goals of the Paris climate agreement.

Participatory Action Research as a Model for Conducting Family Research.

ERIC Educational Resources Information Center

Turnbull, Ann P.; Friesen, Barbara J.; Ramirez, Carmen

1998-01-01

This article discusses a participatory action research (PAR) approach to conducting family research. It proposes a model of PAR implementation level including the options of family members as research leaders and researchers as ongoing advisors, researchers and family members as coresearchers, and researches as leaders, and family members as…

The PLAID graphics analysis impact on the space program

NASA Technical Reports Server (NTRS)

Nguyen, Jennifer P.; Wheaton, Aneice L.; Maida, James C.

1994-01-01

An ongoing project design often requires visual verification at various stages. These requirements are critically important because the subsequent phases of that project might depend on the complete verification of a particular stage. Currently, there are several software packages at JSC that provide such simulation capabilities. We present the simulation capabilities of the PLAID modeling system used in the Flight Crew Support Division for human factors analyses. We summarize some ongoing studies in kinematics, lighting, EVA activities, and discuss various applications in the mission planning of the current Space Shuttle flights and the assembly sequence of the Space Station Freedom with emphasis on the redesign effort.

Networking among young global health researchers through an intensive training approach: a mixed methods exploratory study.

PubMed

Lenters, Lindsey M; Cole, Donald C; Godoy-Ruiz, Paula

2014-01-25

Networks are increasingly regarded as essential in health research aimed at influencing practice and policies. Less research has focused on the role networking can play in researchers' careers and its broader impacts on capacity strengthening in health research. We used the Canadian Coalition for Global Health Research (CCGHR) annual Summer Institute for New Global Health Researchers (SIs) as an opportunity to explore networking among new global health researchers. A mixed-methods exploratory study was conducted among SI alumni and facilitators who had participated in at least one SI between 2004 and 2010. Alumni and facilitators completed an online short questionnaire, and a subset participated in an in-depth interview. Thematic analysis of the qualitative data was triangulated with quantitative results and CCGHR reports on SIs. Synthesis occurred through the development of a process model relevant to networking through the SIs. Through networking at the SIs, participants experienced decreased isolation and strengthened working relationships. Participants accessed new knowledge, opportunities, and resources through networking during the SI. Post-SI, participants reported ongoing contact and collaboration, although most participants desired more opportunities for interaction. They made suggestions for structural supports to networking among new global health researchers. Networking at the SI contributed positively to opportunities for individuals, and contributed to the formation of a network of global health researchers. Intentional inclusion of networking in health research capacity strengthening initiatives, with supportive resources and infrastructure could create dynamic, sustainable networks accessible to global health researchers around the world.

Long-term Hydroclimate and Pacific Salmon Population Linkages Across a Headwater-to-Coast Continuum in Northern British Columbia, Canada: A Perspective From Multiple Tree-Ring Proxy Records

NASA Astrophysics Data System (ADS)

Welsh, C.; Smith, D. J.; Edwards, T.; Prowse, T.

2016-12-01

Ongoing climate change is expected to have lasting impacts on the runoff behaviour of rivers in northern British Columbia, Canada. Of particular concern is the loss of mountain snowpack and greater rainfall totals altering hydrograph characteristics. Sustained deviations in seasonal streamflow will pose significant challenges for effective watershed management. These ongoing changes highlight the importance of improving our understanding of the long-term biophysical linkages between the storage and release of water and downstream freshwater ecosystems. Such integrated research is particularly relevant to fisheries management as fluctuations in populations of Pacific salmon represent a complex and management-relevant biophysical issue in northern Canada. Unfortunately, hydroclimate and salmon productivity records in this region are sparse and of short duration, constraining our understanding of the impact of climate-induced hydrologic changes and biological responses to the last century. Proxy records derived from tree-rings provide annually or seasonally resolved data and have played a prominent role in attempts to establish how hydroclimate has varied in the past. The objective of my doctoral research is to reconstruct the prehistoric hydroclimate and salmon population trends in the Skeena, Nass and Stikine Watersheds using multiple tree-ring proxies to investigate the long-term biophysical linkages extending across a headwater-to-coast continuum in northern British Columbia, Canada. Ring-width, wood density and stable isotope chronologies using a number of mid-to high-elevation tree species will be constructed across each basin and sub-basin area for the purposes of reconstrucing the predominent temperature and precipiation signature that influence streamflow. Preliminary tree-ring δ18O and δ13C-isotope results indicate a strong negative association with mean monthly relative humidity values, suggesting a physiological control by moisture loss. The results of this study highlight the importance of combining several tree-ring parameters and species in order to strengthen streamflow reconstructions. This study is ongoing and has an estimated completion timeframe of spring 2018.

Teaching research: a programme to develop research capacity in undergraduate medical students at the University of KwaZulu-Natal, South Africa.

PubMed

Knight, Stephen E; Van Wyk, Jacqueline M; Mahomed, Saajida

2016-02-16

Improved research ability is a core competency to achieve in health professionals. The Selectives is a three-year, longitudinal, community-based programme within the undergraduate curriculum which aims to develop research capacity in all medical students during the prescribed curriculum. In relation to the programme, the authors describe the types of studies conducted by students, conditions that facilitated their learning, how the experience improved students' knowledge of research and public health and their development of reflective learning practices. A cohort of 212 students completed the Selectives Programme in 2014, and 69 (32 %) completed an anonymous online evaluation thereafter. Data collected include students' perceptions of the research component of Selectives; its impact on their knowledge of research and a documentary analysis of their research protocols and posters. Ethical approval for the ongoing evaluation of the Selectives was sought and obtained from the institutional Biomedical Research Ethics Committee. During Selectives, 75 groups of 2-4 students conducted research studies of primary health care problems in community settings. Each group is assessed on their presentation of research findings as a scientific poster. The Selectives facilitated learning for the majority of the cohort. Students reported positive learning experiences about the research process, including ethics; protocol writing; data processing; dissemination of findings and results; and their use in informing a health promotion intervention. Students reported having gained a better understanding of their strengths and weaknesses through reflective learning from this academic activity. The Selectives is scheduled adjacent to the students' mid-year vacation. This scheduling together with the placement in the students' home community minimizes travel and accommodation costs associated with working outside the academic teaching platform and therefore makes it a cost-effective model in a low resource context. The Selectives has proven beneficial to develop a range of generic and practical research competencies for a full cohort of students enrolled in the undergraduate medical curriculum. The Selectives research process is integrated with learning about population health and the social determinants of health in a primary health care setting.

Using Coaching to Provide Ongoing Support and Supervision to Out-of-School Time Staff. Part 3 in a Series on Implementing Evidence-Based Practices in Out-of-School Time Programs: The Role of Frontline Staff. Research-to-Results Brief. Publication #2009-06

ERIC Educational Resources Information Center

Burkhauser, Mary; Metz, Allison J. R.

2009-01-01

Although skills needed by out-of-school time practitioners can be introduced during training, many skills can only really be learned on the job with ongoing support and supervision provided by a "coach." Research from both the education and out-of-school time fields supports the value of staff coaching as a professional development tool, and staff…

LEVEL IV ECOREGION DELINEATION FOR THE STATE OF WYOMING

EPA Science Inventory

Level III ecoregions were refined and subdivided into level IV for the state of Wyoming in a manner consistent with ecoregion revision and subdivision that has been completed or is on-going in 37 of the conterminous United States. The project was collaborative, involving the scie...

Building operational research capacity in the Pacific

PubMed Central

Viney, K.; Brostrom, R.; Gounder, S.; Khogali, M.; Kishore, K.; Kool, B.; Kumar, A. M. V.; Manzi, M.; Marais, B.; Marks, G.; Linh, N. N.; Ram, S.; Reid, S.; Roseveare, C.; Tayler-Smith, K.; Van den Bergh, R.; Harries, A. D.

2014-01-01

Operational research (OR) in public health aims to investigate strategies, interventions, tools or knowledge that can enhance the quality, coverage, effectiveness or performance of health systems. Attention has recently been drawn to the lack of OR capacity in public health programmes throughout the Pacific Islands, despite considerable investment in implementation. This lack of ongoing and critical reflection may prevent health programme staff from understanding why programme objectives are not being fully achieved, and hinder long-term gains in public health. The International Union Against Tuberculosis and Lung Disease (The Union) has been collaborating with Pacific agencies to conduct OR courses based on the training model developed by The Union and Médecins Sans Frontières Brussels-Luxembourg in 2009. The first of these commenced in 2011 in collaboration with the Fiji National University, the Fiji Ministry of Health, the World Health Organization and other partners. The Union and the Secretariat of the Pacific Community organised a second course for participants from other Pacific Island countries and territories in 2012, and an additional course for Fijian participants commenced in 2013. Twelve participants enrolled in each of the three courses. Of the two courses completed by end 2013, 18 of 24 participants completed their OR and submitted papers by the course deadline, and 17 papers have been published to date. This article describes the context, process and outputs of the Pacific courses, as well as innovations, adaptations and challenges. PMID:26477282

Differences Between Landline and Mobile Phone Users in Sexual Behavior Research.

PubMed

Badcock, Paul B; Patrick, Kent; Smith, Anthony M A; Simpson, Judy M; Pennay, Darren; Rissel, Chris E; de Visser, Richard O; Grulich, Andrew E; Richters, Juliet

2017-08-01

This study investigated differences between the demographic characteristics, participation rates (i.e., agreeing to respond to questions about sexual behavior), and sexual behaviors of landline and mobile phone samples in Australia. A nationally representative sample of Australians aged 18 years and over was recruited via random digit dialing in December 2011 to collect data via computer-assisted telephone interviews. A total of 1012 people (370 men, 642 women) completed a landline interview and 1002 (524 men, 478 women) completed a mobile phone interview. Results revealed that telephone user status was significantly related to all demographic variables: gender, age, educational attainment, area of residence, country of birth, household composition, and current ongoing relationship status. In unadjusted analyses, telephone status was also associated with women's participation rates, participants' number of other-sex sexual partners in the previous year, and women's lifetime sexual experience. However, after controlling for significant demographic factors, telephone status was only independently related to women's participation rates. Post hoc analyses showed that significant, between-group differences for all other sexual behavior outcomes could be explained by demographic covariates. Results also suggested that telephone status may be associated with participation bias in research on sexual behavior. Taken together, these findings highlight the importance of sampling both landline and mobile phone users to improve the representativeness of sexual behavior data collected via telephone interviews.

Building operational research capacity in the Pacific.

PubMed

Bissell, K; Viney, K; Brostrom, R; Gounder, S; Khogali, M; Kishore, K; Kool, B; Kumar, A M V; Manzi, M; Marais, B; Marks, G; Linh, N N; Ram, S; Reid, S; Roseveare, C; Tayler-Smith, K; Van den Bergh, R; Harries, A D

2014-06-21

Operational research (OR) in public health aims to investigate strategies, interventions, tools or knowledge that can enhance the quality, coverage, effectiveness or performance of health systems. Attention has recently been drawn to the lack of OR capacity in public health programmes throughout the Pacific Islands, despite considerable investment in implementation. This lack of ongoing and critical reflection may prevent health programme staff from understanding why programme objectives are not being fully achieved, and hinder long-term gains in public health. The International Union Against Tuberculosis and Lung Disease (The Union) has been collaborating with Pacific agencies to conduct OR courses based on the training model developed by The Union and Médecins Sans Frontières Brussels-Luxembourg in 2009. The first of these commenced in 2011 in collaboration with the Fiji National University, the Fiji Ministry of Health, the World Health Organization and other partners. The Union and the Secretariat of the Pacific Community organised a second course for participants from other Pacific Island countries and territories in 2012, and an additional course for Fijian participants commenced in 2013. Twelve participants enrolled in each of the three courses. Of the two courses completed by end 2013, 18 of 24 participants completed their OR and submitted papers by the course deadline, and 17 papers have been published to date. This article describes the context, process and outputs of the Pacific courses, as well as innovations, adaptations and challenges.

Update on U.S.EPA Cookstove Research Activities

EPA Science Inventory

The presentation includes background information on EPA's stove research, focuses on cookstove testing for air pollutant emissions and energy efficiency, and briefly describes current research activities. Ongoing activities are highlighted, and EPA contacts are provided.

Rabbit Trails, Ephemera, and Other Stories: Feminist Methodology and Collaborative Research.

ERIC Educational Resources Information Center

Burnett, Rebecca E.; Ewald, Helen Rothschild

1994-01-01

Explores the intersections between feminist methodology and collaborative research to identify flashpoints that might derail attempts at collaboration. Analyzes the personal experiences of the authors in four ongoing collaborative research groups. (HB)

Closing the quality gap: revisiting the state of the science (vol. 2: the patient-centered medical home).

PubMed Central

Williams, John W; Jackson, George L; Powers, Benjamin J; Chatterjee, Ranee; Bettger, Janet Prvu; Kemper, Alex R; Hasselblad, Vic; Dolor, Rowena J; Irvine, R Julian; Heidenfelder, Brooke L; Kendrick, Amy S; Gray, Rebecca

2012-01-01

OBJECTIVES As part of the Closing the Quality Gap: Revisiting the State of the Science series of the Agency for Healthcare Research and Quality (AHRQ), this systematic review sought to identify completed and ongoing evaluations of the comprehensive patient-centered medical home (PCMH), summarize current evidence for this model, and identify evidence gaps. DATA SOURCES We searched PubMed®, CINAHL®, and the Cochrane Database of Systematic Reviews for published English-language studies, and a wide variety of databases and Web resources to identify ongoing or recently completed studies. REVIEW METHODS Two investigators per study screened abstracts and full-text articles for inclusion, abstracted data, and performed quality ratings and evidence grading. Our functional definition of PCMH was based on the definition used by AHRQ. We included studies that explicitly claimed to be evaluating PCMH and those that did not but which met our functional definition. RESULTS Seventeen studies with comparison groups evaluated the effects of PCMH (Key Question [KQ] 1). Older adults in the United States were the most commonly studied population (8 of 17 studies). PCMH interventions had a small positive impact on patient experiences (including patient-perceived care coordination) and small to moderate positive effects on preventive care services (moderate strength of evidence [SOE]). Staff experiences were also improved by a small to moderate degree (low SOE). There were too few studies to estimate effects on clinical or most economic outcomes. Twenty-one of 27 studies reported approaches that addressed all 7 major PCMH components (KQ 2), including team-based care, sustained partnership, reorganized care or structural changes to care, enhanced access, coordinated care, comprehensive care, and a systems-based approach to quality. A total of 51 strategies were used to address the 7 major PCMH components. Twenty-two of 27 studies reported information on financial systems used to implement PCMH, implementation strategies, and/or organizational learning strategies for implementing PCMH (KQ 3). The 31 studies identified in the horizon scan of ongoing PCMH studies (KQ 4) were broadly representative of the U.S. health care system, both in geography and in the complexity of private and public health care payers and delivery networks. CONCLUSIONS Published studies of PCMH interventions often have similar broad elements, but precise components of care varied widely. The PCMH holds promise for improving the experiences of patients and staff, and potentially for improving care processes. However, current evidence is insufficient to determine effects on clinical and most economic outcomes. Ongoing studies identified through the horizon scan have potential to greatly expand the evidence base relating to PCMH. PMID:24422946

From Further to Higher Education: Transition as an On-Going Process

ERIC Educational Resources Information Center

Tett, Lyn; Cree, Viviene E; Christie, Hazel

2017-01-01

This paper argues that transition is not a one-off event that occurs when students first enter universities but is an on-going process that is repeated over time. We draw on qualitative data from a longitudinal project on "non-traditional" students who entered a research-intensive university in Scotland direct from further education…

Technology for robotic surface inspection in space

NASA Technical Reports Server (NTRS)

Volpe, Richard; Balaram, J.

1994-01-01

This paper presents on-going research in robotic inspection of space platforms. Three main areas of investigation are discussed: machine vision inspection techniques, an integrated sensor end-effector, and an orbital environment laboratory simulation. Machine vision inspection utilizes automatic comparison of new and reference images to detect on-orbit induced damage such as micrometeorite impacts. The cameras and lighting used for this inspection are housed in a multisensor end-effector, which also contains a suite of sensors for detection of temperature, gas leaks, proximity, and forces. To fully test all of these sensors, a realistic space platform mock-up has been created, complete with visual, temperature, and gas anomalies. Further, changing orbital lighting conditions are effectively mimicked by a robotic solar simulator. In the paper, each of these technology components will be discussed, and experimental results are provided.

Unsolved matters in leprosy: a descriptive review and call for further research.

PubMed

Franco-Paredes, Carlos; Rodriguez-Morales, Alfonso J

2016-05-21

Leprosy, a chronic mycobacterial infection caused by Mycobacterium leprae, is an infectious disease that has ravaged human societies throughout millennia. This ancestral pathogen causes disfiguring cutaneous lesions, peripheral nerve injury, ostearticular deformity, limb loss and dysfunction, blindness and stigma. Despite ongoing efforts in interrupting leprosy transmission, large numbers of new cases are persistently identified in many endemic areas. Moreover, at the time of diagnosis, most newly identified cases have considerable neurologic disability. Many challenges remain in our understanding of the epidemiology of leprosy including: (a) the precise mode and route of transmission; (b) the socioeconomic, environmental, and behavioral factors that promote its transmission; and (c) strategies to achieve early diagnosis and prevent neurologic impairment to reduce the large burden of disability among newly identified cases; and among those who endure long-term disability in spite of completing multidrug therapy.

Economic crime: does personality matter?

PubMed

Alalehto, Tage

2003-06-01

Since the publication of Edwin Sutherland's classical study, White Collar Crime, personality has been treated as completely irrelevant as a cause or as a correlating variable in studies of economic crime. This article questions that thesis. In an ongoing Swedish project studying economic crime in the areas of construction, engineering, and the music industry, 128 informants were interviewed regarding the personal character of the economic criminal compared to that of the law-abiding businessperson. Data were collected from five different regions in Sweden using the Big Five model, the personality model most often used within the field of personality research today. This article compares the results from the interviews with the few international studies that exist regarding economic crimes in these areas and common results are emphasized. It also presents nuanced analyses of the significance of personality in economic crime.

Is Weapon System Cost Growth Increasing? A Quantitative Assessment of Completed and Ongoing Programs

DTIC Science & Technology

2007-01-01

analysis of the point at five years past MS B may be prudent. 49 APPENDIX A Completed Programs Aircraft A-7D Corsair II Data are from September 1969...rocket vehicle used to deploy satellites to higher orbits from the space shuttle payload bay or atop the Titan IV booster. SARs report that quantities...Cost Growth Increasing? Other Common Strategic Rotary Launcher This program designed and built mechanisms housed within bomb bays to accommodate the

First Choice for Energy Support. Defense Energy Support Center Fact Book, Fiscal Year 2004, Twenty-Seventh Edition

DTIC Science & Technology

2004-01-01

proceeding. UTILITY PRIVATIZATION SUPPORT Ongoing Actions FY 2004 – (Total Value - $488.1M) Fort Knox, KY – Wastewater/Stormwater Fort Monroe, VA...Iraqi civilian populace. Upon completion of the TF-RIO contracts in August 2004 , between April 2004 and August 2004 over 162,162,039 gallons of...Air Force decision to order ASTM D 975 product throughout COG 6 beginning in 2004 marked the successful completion of DESC’s automotive diesel

F 35 JOINT STRIKE FIGHTER DOD Needs to Complete Developmental Testing Before Making Significant New Investments

DTIC Science & Technology

2017-04-01

from contractors . Until Block 3F testing is complete, DOD will not have the knowledge it needs to present a sound business case for Block 4. Second...January 2017 the details of this plan were unclear because DOD’s 2018 budget was not final and negotiations with the contractors were ongoing...management reports and historical test data; discussed key aspects of F-35 development with program management and contractor officials; and compared

Coping styles as moderating the relationships between terrorist attacks and well-being outcomes.

PubMed

Braun-Lewensohn, Orna; Celestin-Westreich, Smadar; Celestin, Leon-Patrice; Verleye, Gino; Verté, Dominique; Ponjaert-Kristoffersen, Ingrid

2009-06-01

This study aims to explore use of coping strategies among adolescents and their relationships with well being in the context of ongoing terrorism. Furthermore, we aim to explore to what extent coping styles in addition to exposure variables explain well being of adolescents facing ongoing terror. During September 2003, after three years of ongoing terror attacks, 913 Israeli adolescents aged 12-18 years, completed the following questionnaires during regular class sessions: Demographics, Achenbach's Youth Self Report; Exposure to Terror and Post Traumatic Stress (PTS) questionnaire; Adolescent Coping Scale (ACS) and Brief Symptoms Inventory. Adolescents employed mainly problem solving strategies which mean they have the capacity to cope well in spite of stressful events. Emotional focused coping was associated with PTS and mental health problems. Regression analysis of different exposure and coping variables revealed that exposure, appraisal (subjective exposure) and coping styles explained 26-37% of the variance of different psychological problems. The findings highlight the importance of appraisal (subjective exposure) and coping strategies, for understanding adolescents' mental health outcomes. Moreover, these findings are relevant to the development of prevention/intervention programs that facilitate youth's cognitive and emotional adjustments to ongoing trauma risks and terror threats.

Women's Health and Complementary Approaches

MedlinePlus

... Information Center Ongoing Medical Studies Find Active Medical Research Studies on Cranberry (ClinicalTrials.gov) Find Active Medical Research Studies on Menopause (ClinicalTrials.gov) Safety Information Dream Body ...

Behavioral Health and Performance at NASA JSC: Recent Successes and Future Plan for BHP Research and Operations

NASA Technical Reports Server (NTRS)

Leveton, L. B.; VanderArk, S. T.

2014-01-01

The Behavioral Health and Performance discipline at NASA Johnson Space Center is organized into two distinct Divisions (Biomedical Research and Environmental Science Division and Space and Clinical Operations Division) but is integrated and interrelated in its day-to-day work. Ongoing operations supporting NASA's spaceflight goals benefit from the research portfolios that address risks to mission success. Similarly, these research portfolios are informed by operations to ensure investigations stay relevant given the dynamic environment of spaceflight. There are many success stories that can be presented where initial work begun as a BHP Research project, and funded through the Human Research Program, was fully implemented in operations or addressed an operational need. Examples include improving effectiveness of the debriefings used within Mission Control by the Mission Operations Directorate and countermeasures for fatigue management. There is also ongoing collaboration with research and operations for developing selection methods for future generation astronauts, and to enhance and inform the current family support function. The objective of this panel is to provide examples of recent success stories, describe areas where close collaboration is benefitting ongoing research and operations, and summarize how this will come together as NASA plans for the one year ISS mission - a unique opportunity for both BHP operations and research to learn more about preparing and supporting crewmembers for extended missions in space. The proposed panel will be comprised of six presentations, each describing a unique aspect of research or operations and the benefits to current and future spaceflight.

Organic Research Activities of the USDA’s Agricultural Research Service

USDA-ARS?s Scientific Manuscript database

Organic research is a vital and ongoing part of the overall ARS research portfolio and occurs at approximately 20 % of ARS research locations across the United States. The vision for ARS organic agriculture research is to help the organic industry overcome the challenges it faces related to producti...

Researching across Boundaries and Borders: The Challenges for Research

ERIC Educational Resources Information Center

Bowl, Marion; Cooke, Sandra; Hockings, Christine

2008-01-01

This article explores some of the challenges of conducting action research in higher education. It arises from an ongoing research project funded by the Economic and Social Research Council's Teaching and Learning Research Programme (ESRC/TLRP), "Learning and Teaching for Social Diversity and Difference", which examines the dynamics of…

Improving Project Management with Simulation and Completion Distribution Functions

NASA Technical Reports Server (NTRS)

Cates, Grant R.

2004-01-01

Despite the critical importance of project completion timeliness, management practices in place today remain inadequate for addressing the persistent problem of project completion tardiness. A major culprit in late projects is uncertainty, which most, if not all, projects are inherently subject to. This uncertainty resides in the estimates for activity durations, the occurrence of unplanned and unforeseen events, and the availability of critical resources. In response to this problem, this research developed a comprehensive simulation based methodology for conducting quantitative project completion time risk analysis. It is called the Project Assessment by Simulation Technique (PAST). This new tool enables project stakeholders to visualize uncertainty or risk, i.e. the likelihood of their project completing late and the magnitude of the lateness, by providing them with a completion time distribution function of their projects. Discrete event simulation is used within PAST to determine the completion distribution function for the project of interest. The simulation is populated with both deterministic and stochastic elements. The deterministic inputs include planned project activities, precedence requirements, and resource requirements. The stochastic inputs include activity duration growth distributions, probabilities for events that can impact the project, and other dynamic constraints that may be placed upon project activities and milestones. These stochastic inputs are based upon past data from similar projects. The time for an entity to complete the simulation network, subject to both the deterministic and stochastic factors, represents the time to complete the project. Repeating the simulation hundreds or thousands of times allows one to create the project completion distribution function. The Project Assessment by Simulation Technique was demonstrated to be effective for the on-going NASA project to assemble the International Space Station. Approximately $500 million per month is being spent on this project, which is scheduled to complete by 2010. NASA project stakeholders participated in determining and managing completion distribution functions produced from PAST. The first result was that project stakeholders improved project completion risk awareness. Secondly, using PAST, mitigation options were analyzed to improve project completion performance and reduce total project cost.

77 FR 60107 - Marine Mammals; File No. 17298

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-02

... a permit to collect, import, export, and receive marine mammal parts for scientific research. DATES... objective of this application is to support multiple ongoing research programs at the Mystic Aquarium... continued research on these species. [[Page 60108

Update on ongoing tank car crashworthiness research : predicted performance and fabrication approach

DOT National Transportation Integrated Search

2008-04-22

Research is currently underway to develop strategies for maintaining the structural integrity of railroad tank cars carrying hazardous materials during collisions. This research, sponsored by the Federal Railroad Administration (FRA), has focused on ...

GOALS AND CURRENT RESEARCH OF EPA'S STREAM RESTORATION RESEARCH PROGRAM

EPA Science Inventory

The US EPA is involved in ongoing research on stream and riparian restoration. This presentation is designed to discuss current EPA research efforts, identify key issues in the science and practice of stream restoration, and to help frame a future National Research Council study...

Supporting Tertiary Students with a Disability or Mental Illness. Good Practice Guide

ERIC Educational Resources Information Center

National Centre for Vocational Education Research (NCVER), 2015

2015-01-01

Having a disability or ongoing ill health (including mental health conditions) can significantly disrupt an individual's educational attainment and employment prospects, potentially creating lifelong social and economic disadvantage. These students may need additional support to help them successfully complete their studies. In addition, education…

College Peer Counselor Teaching Modalities: Sequelae in the Life and Work of Graduates

ERIC Educational Resources Information Center

Hatcher, Sherry L.; Shields, C. Comfort; Wierba, Elizabeth E.; Hatcher-Ross, Juliet L.; Hanley, Steven J.

2014-01-01

This study examined extended influences of peer helping courses on graduates' self-reported experiences of interpersonal relationships, communication skills, and ongoing engagement with the training. The 109 participants included 49 college graduates who completed a peer counseling theory course, 47 graduated psychology concentrators who took a…

Searching for Grey Literature for Systematic Reviews: Challenges and Benefits

ERIC Educational Resources Information Center

Mahood, Quenby; Van Eerd, Dwayne; Irvin, Emma

2014-01-01

There is ongoing interest in including grey literature in systematic reviews. Including grey literature can broaden the scope to more relevant studies, thereby providing a more complete view of available evidence. Searching for grey literature can be challenging despite greater access through the Internet, search engines and online bibliographic…

United States housing, 2013

Treesearch

Delton Alderman

2016-01-01

This publication provides an overview of the 2013 U.S. housing market, including updated information and data, and is part of an ongoing series of quarterly and annual housing reports that provide historical information on housing permits, starts, houses under construction, and completions. In addition, short briefs present information regarding house sales,...

Renaissance of antibiotics against difficult infections: Focus on oritavancin and new ketolides and quinolones.

PubMed

Van Bambeke, Françoise

2014-11-01

Lipoglycopeptide, ketolide, and quinolone antibiotics are currently in clinical development, with specific advantages over available molecules within their respective classes. The lipoglycopeptide oritavancin is bactericidal against MRSA, vancomycin-resistant enterococci, and multiresistant Streptococcus pneumoniae, and proved effective and safe for the treatment of acute bacterial skin and skin structure infection (ABSSSI) upon administration of a single 1200 mg dose (two completed phase III trials). The ketolide solithromycin (two phase III studies recruiting for community-acquired pneumonia) shows a profile of activity similar to that of telithromycin, but in vitro data suggest a lower risk of hepatotoxicity, visual disturbance, and aggravation of myasthenia gravis due to reduced affinity for nicotinic receptors. Among quinolones, finafloxacin and delafloxacin share the unique property of an improved activity in acidic environments (found in many infection sites). Finafloxacin (phase II completed; activity profile similar to that of ciprofloxacin) is evaluated for complicated urinary tract and Helicobacter pylori infections. The other quinolones (directed towards Gram-positive pathogens) show improved activity on MRSA and multiresistant S. pneumoniae compared to current molecules. They are in clinical evaluation for ABSSSI (avarofloxacin (phase II completed), nemonoxacin and delafloxacin (ongoing phase III)), respiratory tract infections (zabofloxacin and nemonoxacin (ongoing phase III)), or gonorrhea (delafloxacin).

Design challenges in transdiagnostic psychotherapy research: Comparing Transdiagnostic Behavior Therapy (TBT) to existing evidence-based psychotherapy in veterans with affective disorders.

PubMed

Gros, Daniel F

2015-07-01

To address the limitations of disorder-specific approaches, newer transdiagnostic approaches to psychotherapy have been developed to provide a single treatment that is capable of addressing several, related disorders. However, the recruitment of multiple diagnoses presents many challenges to the traditional design of psychotherapy randomized controlled trials (RCTs). The goal of the manuscript is to present the challenges and rationale for designing a RCT for transdiagnostic treatment to inform and aid in the development of future investigations. A recently funded and ongoing RCT for Transdiagnostic Behavior Therapy (TBT) is used as an example to discuss the related design challenges. The TBT study involves the recruitment of 96 veteran participants with any of the following eight principal diagnoses: posttraumatic stress disorder, panic disorder, social anxiety disorder, obsessive compulsive disorder, generalized anxiety disorder, specific phobia, major depressive disorder, or persistent depressive disorder. Within the TBT study, participants will complete a semi-structured diagnostic interview and a series of transdiagnostic self-report measures to determine eligibility and assess baseline symptomatology. Qualifying participants will be randomized to TBT or control psychotherapy. Additional assessments will be completed at post-treatment and 6-month follow-up. Due to the transdiagnostic nature of the sample, adjustments to the recruitment and randomization procedures, selection of measures, selection of control psychotherapy, and analysis plan were required. These adjustments have implications to future trials on transdiagnostic psychotherapy protocols as well as future research in line with the transdiagnostic focus of the National Institute of Mental Health's Research Domain Criteria (RDoC) funding strategy. Published by Elsevier Inc.

[Scientific significance and prospective application of digitized virtual human].

PubMed

Zhong, Shi-zhen

2003-03-01

As a cutting-edge research project, digitization of human anatomical information combines conventional medicine with information technology, computer technology, and virtual reality technology. Recent years have seen the establishment of, or the ongoing effort to establish various virtual human models in many countries, on the basis of continuous sections of human body that are digitized by means of computational medicine incorporating information technology to quantitatively simulate human physiological and pathological conditions, and to provide wide prospective applications in the fields of medicine and other disciplines. This article addresses 4 issues concerning the progress in virtual human model researches as the following: (1) Worldwide survey of sectioning and modeling of visible human. American visible human database was completed in 1994, which contains both a male and a female datasets, and has found wide application internationally. South Korea also finished the data collection for a male visible Korean human dataset in 2000. (2) Application of the dataset of Visible Human Project (VHP). This dataset has yielded plentiful fruits in medical education and clinical research, and further plans are proposed and practiced to construct a Physical Human and Physiological Human . (3) Scientific significance and prospect of virtual human studies. Digitized human dataset may eventually contribute to the development of many new high-tech industries. (4) Progress of virtual Chinese human project. The 174th session of Xiangshang Science Conferences held in 2001 marked the initiation of digitized virtual human project in China, and some key techniques have been explored. By now the data-collection process for 4 Chinese virtual human datasets have been successfully completed.

On the Relationship Between Effort Toward an Ongoing Task and Cue Detection in Event-Based Prospective Memory

ERIC Educational Resources Information Center

Marsh, Richard L.; Hicks, Jason L.; Cook, Gabriel I.

2005-01-01

In recent theories of event-based prospective memory, researchers have debated what degree of resources are necessary to identify a cue as related to a previously established intention. In order to simulate natural variations in attention, the authors manipulated effort toward an ongoing cognitive task in which intention-related cues were embedded…

A Kenyan Cloud School. Massive Open Online & Ongoing Courses for Blended and Lifelong Learning

ERIC Educational Resources Information Center

Jobe, William

2013-01-01

This research describes the predicted outcomes of a Kenyan Cloud School (KCS), which is a MOOC that contains all courses taught at the secondary school level in Kenya. This MOOC will consist of online, ongoing subjects in both English and Kiswahili. The KCS subjects offer self-testing and peer assessment to maximize scalability, and digital badges…

An Epidemiologic Study of Genetic Variation in Hormonal Pathways in Relation to the Effect of Hormone Replacement Therapy on Breast Cancer Risk

DTIC Science & Technology

2007-04-01

active learning techniques in Introduction to Epidemiology Ongoing5 W81XWH-06-1-0312 Reding, Kerryn 7 TASK STATUS of FUTURE TASKS Task 3...Apply for and obtain IRB renewal Ongoing task Task 4: Training-related Work (Months 13-36) a. Present research findings on active learning at

"A different kind of beauty": scientific and architectural style in I.M. Pei's Mesa Laboratory and Louis Kahn's Salk Institute.

PubMed

Leslie, Stuart W

2008-01-01

I.M. Pei's Mesa Laboratory for the National Center for Atmospheric Research in Boulder, Colorado, and Louis Kahn's Salk Institute in La Jolla, California, are rare examples of laboratories as celebrated for their architecture as for their scientific contributions. Completed in the mid-1960s, these signature buildings still express the scientific style of their founding directors, Walter Roberts and Jonas Salk. yet in commissioning their laboratories, Roberts and Salk had to work with architects as strong-willed as themselves. A close reading of the two laboratories reveals the ongoing negotiations and tensions in collaborations between visionary scientist and visionary architect. Moreover, Roberts and Salk also had to become architects of atmospheric and biomedical sciences. For laboratory architecture, however flexible in theory, necessarily stabilizes scientific practice, since a philosophy of research is embedded in the very structure of the building and persists far longer than the initial vision and mission that gave it life. Roberts and Salk's experiences suggest that even the most carefully designed laboratories must successfully adapt to new disciplinary configurations, funding opportunities, and research priorities, or risk becoming mere architectural icons.

Gaining ground on a cure through synergy: combining checkpoint inhibitors with cancer vaccines.

PubMed

Vreeland, T J; Clifton, G T; Herbert, G S; Hale, D F; Jackson, D O; Berry, J S; Peoples, G E

2016-12-01

The approval of multiple checkpoint inhibitors (CPIs) for the treatment of advanced malignancies has sparked an explosion of research in the field of cancer immunotherapy. Despite the success of these medications, a large number of patients with advanced malignancy do not benefit from therapy. Early research indicates that a therapeutic combination of cancer vaccines with checkpoint inhibitors may lead to synergistic effects and higher response rates than monotherapy. Areas covered: This paper summarizes the previously completed and ongoing research on this exciting combination, including the use of the tumor lysate, particle-loaded dendritic cell (TLPLDC) vaccine combined with checkpoint inhibitors in advanced melanoma. Expert commentary: Increasing experience with CPIs has led to improved understanding of which patients may benefit and it is increasingly clear that the presence of a pre-existing immune response to the tumor, along with tumor-infiltrating lymphocytes, is key to the success of CPIs. One exciting possibility for the future is the addition of a cancer vaccine to CPI therapy, eliciting these crucial T cells, which can then be augmented and protected by the CPI. A number of current and future studies are addressing this very exciting combination therapy.

The timing of introduction of complementary foods and later health.

PubMed

Agostoni, Carlo; Przyrembel, Hildegard

2013-01-01

Complementary food is needed when human milk (or infant formula) alone is no longer sufficient for nutritional reasons. The timing of introduction needs to be determined on an individual basis although 6 months of exclusive breastfeeding can be recommended for most healthy term infants. Solid foods are intended to 'complement' ongoing breastfeeding with those dietary items whose intake has become marginal or insufficient. Both breastfeeding and complementary feeding can have direct or later consequences on health. Possible short-term health effects concern growth velocity and infections while possible long-term effects may relate to obesity, cardiovascular disease, autoimmunity (celiac disease and type 1 diabetes) and atopic disorders. For most of these it is impossible on the basis of the available evidence to conclude on the age when risks related to the start of complementary feeding are lowest or highest, with the possible exception of infections and early growth velocity. For undesirable health consequences, whilst potential mechanisms are recognized, the evidence from mostly observational studies is insufficient and requires more and prospective research. While the 6-month goal is desirable, introduction of suitable complementary food after 4 completed months with ongoing breastfeeding can be considered without adverse health consequences for infants living in affluent countries. Even less evidence on the consequences of the timing of complementary food introduction is available for formula-fed infants. Copyright © 2013 S. Karger AG, Basel.

Cohort profile: design and first results of the Dutch IBD Biobank: a prospective, nationwide biobank of patients with inflammatory bowel disease

PubMed Central

Spekhorst, Lieke M; Imhann, Floris; Festen, Eleonora AM; van Bodegraven, Ad A; de Boer, Nanne KH; Bouma, Gerd; Fidder, Herma H; D’Haens, Geert; Hoentjen, Frank; Hommes, Daan W; de Jong, Dirk J; Löwenberg, Mark; Maljaars, PW Jeroen; van der Meulen-de Jong, Andrea E; Oldenburg, Bas; Pierik, Marieke J; Ponsioen, Cyriel Y; Stokkers, Pieter C; Verspaget, Hein W; Visschedijk, Marijn C; van der Woude, C Janneke; Dijkstra, Gerard; Weersma, Rinse K

2017-01-01

Purpose The Dutch IBD Biobank aims to facilitate the discovery of predictors for individual disease course and treatment response in patients with inflammatory bowel disease (IBD). In this paper, we aim to describe the establishment of the Dutch IBD Biobank, including the facilitators and barriers to establishment. Moreover, we aim to provide a complete overview of the content of the Dutch IBD Biobank. Participants Since 2007, every patient with IBD treated in one of the eight Dutch university medical centres is asked to participate in the Dutch IBD Biobank in which 225 standardised IBD-related data items and biomaterials, such as serum, DNA, biopsies and a stool sample, are collected. Findings to date As of June 2014, the Dutch IBD Biobank had enrolled 3388 patients with IBD: 2118 Crohn’s disease (62.5%), 1190 ulcerative colitis (35.1%), 74 IBD-unclassified (2.2%) and 6 IBD-indeterminate (0.2%). The inclusion of patients with IBD is ongoing. The quality of the biomaterials is good and serum, DNA and biopsies have been used in newly published studies. Future plans The genotyping (750 000 genetic variants) of all participants of the Dutch IBD Biobank is currently ongoing, enabling more genetic research. In addition, all participants will start reporting disease activity and outcome measures using an online platform and mobile app. PMID:29122790

Life after the game--injury profile of past elite Australian football players.

PubMed

King, Tyler; Rosenberg, Michael; Braham, Rebecca; Ferguson, Renee; Dawson, Brian

2013-07-01

To investigate the long-term health and well-being of past elite Australian Football League (AFL) players, with particular emphasis on the effect of playing injuries on current lifestyle. Cross sectional survey. A health and well-being survey, completed by past AFL players (n=592) with mean (±SD) age of 55.1 y (±15.8) and playing career of 7.7 y (±4.1) sought information on demographics, education and employment, subjective well-being, lifestyle behaviours, physical health, disease prevalence, community and social structures, and playing history. A majority of past players experienced serious injuries (76%) and concussion (73%) throughout their career, both increasing significantly with the number of games played. Of those who received injuries, 60% require on-going treatment, yet only 6% receive treatment costs covered by their club or the AFL Players' Association. A large proportion (64%) of respondents are affected in daily life from previous AFL injuries. AFL careers are compounded by high injury rates, including loss of consciousness with a high incidence of multiple concussions amongst those players reporting a serious injury. Greater number of injuries received will further the likelihood of requiring on-going treatment and being affected later in life. Additional research and planning may be important in assisting other improvements in the quality of life of past AFL players. Copyright © 2012 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

Lessons Learned: The Evolution of an Undergraduate Research Program

ERIC Educational Resources Information Center

Smith, Gregory; Laker, Lauren; Tesch, Debbie

2013-01-01

Undergraduate research programs are commonplace at many universities. However, little research has been conducted to evaluate their ongoing and long-term effectiveness from the standpoint of the undergraduate student researcher. In an effort to gain perspective from the student researcher, including their thoughts on such a program, a survey was…

ACCELERATED EXTRACTION OF ORGANIC POLLUTANTS USING MICROWAVE ENERGY

EPA Science Inventory

This study is part of an ongoing U.S. Environmental Protection Agency research program, carried out by the National Exposure Research Laboratory, Characterization Research Division-Las Vegas (formerly Environmental Monitoring Systems Laboratory-Las Vegas), addresses new sample pr...

Operational algorithm development and refinement approaches

NASA Astrophysics Data System (ADS)

Ardanuy, Philip E.

2003-11-01

Next-generation polar and geostationary systems, such as the National Polar-orbiting Operational Environmental Satellite System (NPOESS) and the Geostationary Operational Environmental Satellite (GOES)-R, will deploy new generations of electro-optical reflective and emissive capabilities. These will include low-radiometric-noise, improved spatial resolution multi-spectral and hyperspectral imagers and sounders. To achieve specified performances (e.g., measurement accuracy, precision, uncertainty, and stability), and best utilize the advanced space-borne sensing capabilities, a new generation of retrieval algorithms will be implemented. In most cases, these advanced algorithms benefit from ongoing testing and validation using heritage research mission algorithms and data [e.g., the Earth Observing System (EOS)] Moderate-resolution Imaging Spectroradiometer (MODIS) and Shuttle Ozone Limb Scattering Experiment (SOLSE)/Limb Ozone Retreival Experiment (LORE). In these instances, an algorithm's theoretical basis is not static, but rather improves with time. Once frozen, an operational algorithm can "lose ground" relative to research analogs. Cost/benefit analyses provide a basis for change management. The challenge is in reconciling and balancing the stability, and "comfort," that today"s generation of operational platforms provide (well-characterized, known, sensors and algorithms) with the greatly improved quality, opportunities, and risks, that the next generation of operational sensors and algorithms offer. By using the best practices and lessons learned from heritage/groundbreaking activities, it is possible to implement an agile process that enables change, while managing change. This approach combines a "known-risk" frozen baseline with preset completion schedules with insertion opportunities for algorithm advances as ongoing validation activities identify and repair areas of weak performance. This paper describes an objective, adaptive implementation roadmap that takes into account the specific maturities of each system"s (sensor and algorithm) technology to provide for a program that contains continuous improvement while retaining its manageability.

Skills, systems and supports: An Aboriginal Community Controlled Health Service (Apunipima) approach to building health promotion evaluation capacity of staff.

PubMed

Nichols, Nina; McFarlane, Kathryn; Gibson, Priscilla; Millard, Fiona; Packer, Andrew; McDonald, Malcolm

2018-04-01

Building the health promotion evaluation capacity of a workforce requires more than a focus on individual skills and confidence. We must also consider the organisational systems and supports that enable staff to embed learnings into practice. This paper describes the processes used to build health promotion evaluation capacity of staff in an Aboriginal Community Controlled Health Service (ACCHS). To build health promotion evaluation capacity three approaches were used: (i) workshops and mentoring; (ii) strengthening systems to support program reporting; and (iii) recruitment of staff with skills and experience. Pre- and post-questionnaires determined levels of individual skills and confidence, updated systems were assessed for adequacy to support new health promotion practices and surveys captured the usefulness of workshops and mentoring. There was increased participant skills and confidence. Participants completed program impact evaluation reports and results were successfully presented at national conferences. The health promotion team was then able to update in-house systems to support new health promotion practices. Ongoing collaboration with experienced in-house researchers provided basic research training and professional mentoring. Building health promotion evaluation capacity of staff in an ACCHS can be achieved by providing individual skill development, strengthening organisational systems and utilising professional support. SO WHAT?: Health promotion practitioners have an ongoing professional obligation to improve the quality of routine practice and embrace new initiatives. This report outlines a process of building evaluation capacity that promotes quality reporting of program impacts and outcomes, reflects on ways to enhance program strengths, and communicates these findings internally and to outside professional bodies. This is particularly significant for ACCHSs responsible for addressing the high burden of preventable disease in Aboriginal and Torres Strait Islander populations. © 2017 Australian Health Promotion Association.

Rain Garden Research at EPA’s Urban Watershed Research Facility

EPA Science Inventory

Summary of the ongoing rain garden research at UWMB. The context for the study was described as well as the experimental design for the full-scale study, instrumentation, and stormwater collection system. Supporting bench scale research on hydraulic properties of media and soil...

From in vivo to in vitro: How the Guatemala STD Experiments Transformed Bodies Into Biospecimens.

PubMed

Spector-Bagdady, Kayte; Lombardo, Paul A

2018-06-01

Policy Points: While most scholarship regarding the US Public Health Service's STD experiments in Guatemala during the 1940s has focused on the intentional exposure experiments, secondary research was also conducted on biospecimens collected from these subjects. These biospecimen experiments continued after the Guatemala grant ended, and the specimens were used in conjunction with those from the Tuskegee syphilis experiments for ongoing research. We argue there should be a public accounting of whether there are still biospecimens from the Guatemala and Tuskegee experiments held in US government biorepositories today. If such specimens exist, they should be retired from US government research archives because they were collected unethically as understood at the time. The US Public Health Service's Guatemala STD experiments (1946-1948) included intentional exposure to pathogens and testing of postexposure prophylaxis methods for syphilis, gonorrhea, and chancroid in over 1,300 soldiers, commercial sex workers, prison inmates, and psychiatric patients. Though the experiments had officially ended, the biospecimens collected from these subjects continued to be used for research at least into the 1950s. We analyzed historical documents-including clinical and laboratory records, correspondence, final reports, and medical records-for information relevant to these biospecimen experiments from the US National Archives. In addition, we researched material from past governmental investigations into the Guatemala STD experiments, including those of the US Presidential Commission for the Study of Bioethical Issues and the Guatemalan Comisión Presidencial para el Esclarecimiento de los Experimentos Practicados con Humanos en Guatemala. Identified spinal fluid, blood specimens, and tissue collected during the Guatemala diagnostic methodology and intentional exposure experiments were subsequently distributed to laboratories throughout the United States for use in ongoing research until at least 1957. Five psychiatric patient subjects involved in these biospecimen experiments died soon after experimental exposure to STDs. The same US government researchers working with the Guatemala biospecimens after the exposure experiments ended were also working with specimens taken from the Tuskegee syphilis study. There should be a complete public accounting of whether biospecimens from the Guatemala and Tuskegee experiments are held in US government biorepositories today. If they still exist, these specimens should be retired from such biorepositories and their future disposition determined by stakeholders, including representatives from the communities from which they were derived. © 2018 Milbank Memorial Fund.

A Video Introduction to Psychology: Enhancing Research Interest and Participation

ERIC Educational Resources Information Center

Sacco, Donald F.; Bernstein, Michael J.

2010-01-01

To assess the extent to which a video about psychological research would heighten introductory psychology students' interest and participation in research studies, we created a video about ongoing research at our university, the value of research participation, and course requirements for the research experience. Instructors in 4 courses (N = 471…

Exploring Applications of Radiomics in Magnetic Resonance Imaging of Head and Neck Cancer: A Systematic Review.

PubMed

Jethanandani, Amit; Lin, Timothy A; Volpe, Stefania; Elhalawani, Hesham; Mohamed, Abdallah S R; Yang, Pei; Fuller, Clifton D

2018-01-01

Radiomics has been widely investigated for non-invasive acquisition of quantitative textural information from anatomic structures. While the vast majority of radiomic analysis is performed on images obtained from computed tomography, magnetic resonance imaging (MRI)-based radiomics has generated increased attention. In head and neck cancer (HNC), however, attempts to perform consistent investigations are sparse, and it is unclear whether the resulting textural features can be reproduced. To address this unmet need, we systematically reviewed the quality of existing MRI radiomics research in HNC. Literature search was conducted in accordance with guidelines established by Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Electronic databases were examined from January 1990 through November 2017 for common radiomic keywords. Eligible completed studies were then scored using a standardized checklist that we developed from Enhancing the Quality and Transparency of Health Research guidelines for reporting machine-learning predictive model specifications and results in biomedical research, defined by Luo et al. (1). Descriptive statistics of checklist scores were populated, and a subgroup analysis of methodology items alone was conducted in comparison to overall scores. Sixteen completed studies and four ongoing trials were selected for inclusion. Of the completed studies, the nasopharynx was the most common site of study (37.5%). MRI modalities varied with only four of the completed studies (25%) extracting radiomic features from a single sequence. Study sample sizes ranged between 13 and 118 patients (median of 40), and final radiomic signatures ranged from 2 to 279 features. Analyzed endpoints included either segmentation or histopathological classification parameters (44%) or prognostic and predictive biomarkers (56%). Liu et al. (2) addressed the highest number of our checklist items (total score: 48), and a subgroup analysis of methodology checklist items alone did not demonstrate any difference in scoring trends between studies [Spearman's ρ = 0.94 ( p  < 0.0001)]. Although MRI radiomic applications demonstrate predictive potential in analyzing diverse HNC outcomes, methodological variances preclude accurate and collective interpretation of data.

ALK-targeted therapy for lung cancer: ready for prime time.

PubMed

Husain, Hatim; Rudin, Charles M

2011-06-01

Lung cancer remains the leading cause of cancer-related death in the United States. Ongoing research into the molecular basis of lung cancer has yielded insight into various critical pathways that are deregulated in lung tumorigenesis, and in particular key driver mutations integral to cancer cell survival and proliferation. One of the most recent examples of this has been definition of translocations and functional dysregulation of the anaplastic lymphoma kinase (ALK) gene in a subset of patients with non-small-cell lung cancer. The pace of research progress in this area has been remarkable: chromosomal rearrangements involving this gene in lung cancer were first reported in 2007 by a team of investigators in Japan. Less than 3 years later, an early-phase clinical trial of a targeted ALK inhibitor has yielded impressive responses in patients with advanced lung cancer containing ALK rearrangements, and mechanisms of acquired resistance to ALK-targeted therapy are being reported. A definitive study randomizing patients with ALK-mutant lung cancer to crizotinib (also known as PF-02341066 or 1066) versus standard therapy has recently completed enrollment.Taken together, these data describe a trajectory of research progress from basic discovery science to real-world implementation that should serve as a model for future integration of preclinical and clinical therapeutic research.

Implementation of an Adaptive Controller System from Concept to Flight Test

NASA Technical Reports Server (NTRS)

Larson, Richard R.; Burken, John J.; Butler, Bradley S.

2009-01-01

The National Aeronautics and Space Administration Dryden Flight Research Center (Edwards, California) is conducting ongoing flight research using adaptive controller algorithms. A highly modified McDonnell-Douglas NF-15B airplane called the F-15 Intelligent Flight Control System (IFCS) was used for these algorithms. This airplane has been modified by the addition of canards and by changing the flight control systems to interface a single-string research controller processor for neural network algorithms. Research goals included demonstration of revolutionary control approaches that can efficiently optimize aircraft performance for both normal and failure conditions, and to advance neural-network-based flight control technology for new aerospace systems designs. Before the NF-15B IFCS airplane was certified for flight test, however, certain processes needed to be completed. This paper presents an overview of these processes, including a description of the initial adaptive controller concepts followed by a discussion of modeling formulation and performance testing. Upon design finalization, the next steps are: integration with the system interfaces, verification of the software, validation of the hardware to the requirements, design of failure detection, development of safety limiters to minimize the effect of erroneous neural network commands, and creation of flight test control room displays to maximize human situational awareness.

Shaping the professional landscape through research, advocacy and education - an Australian perspective.

PubMed

Siemensma, Gemma; Ritchie, Ann; Lewis, Suzanne

2017-06-01

This article is the first in a new series in this regular feature. The intention of the series is to look at important global developments in health science libraries. Librarians will be invited to share with HILJ readers key initiatives in their country or region. These articles should serve as a road map, describing the key changes in the field and exploring factors driving these changes. We initiate this series with an article by three Australian librarians who use research findings to depict the evolving professional landscape in their country. The starting point of their analysis is a report completed in 2011 which looked into likely future workforce and education requirements for health library professionals. The authors trace the achievements since then, most notably in the areas of research, advocacy and education. Clearly, a great deal has been achieved leading to a greater return on investment. The authors maintain that the key to shaping the profession and enhancing the status of librarians is ongoing professional development. To this end, Australia is promoting a systematic, competency based health specialist certification. Finally, they identify trends impacting on health librarianship, such as the growing importance of research data management and consumer health literacy. JM. © 2017 Health Libraries Group.

The Impact of NSF-funded Physics Education Research at the University of Washington

NASA Astrophysics Data System (ADS)

Heron, Paula

2015-03-01

It is now well known that many students who complete introductory physics courses are unable to apply fundamental concepts in situations that involve qualitative reasoning. Systematic investigations have helped researchers understand why so many students fail to develop robust and coherent conceptual frameworks, and have led to the development of new teaching practices and materials that are far more effective than conventional ones. The Physics Education Group at the University of Washington has played a leading role in raising awareness of the need to improve instruction, and in supporting physics faculty in their efforts to do so. With support from the National Science Foundation, the group has helped build a research base that instructors can draw on, and has produced practical, flexible instructional materials that promote deeper learning in physics classrooms. Both ``Tutorials in Introductory Physics'' (Pearson, 2002) and ``Physics by Inquiry'' (Wiley, 1996) have been developed in an iterative process in which ongoing assessment of student learning plays an integral role. These materials have had a widespread and significant impact on physics teaching and on student learning from kindergarten through graduate school. In this talk I will describe the role of research in curriculum development, and speculate on the next generation of tools and resources to support physics teaching and learning.

Tenth workshop on seedling physiology and growth problems in oak plantings

Treesearch

Brian Roy Lockhart; Emile S. Gardiner; Daniel C. Dey

2008-01-01

Research results and ongoing research activities in field performance of oak plantings, seedling propagation, genetics, acorn germination, and natural regeneration of oaks are described in 15 abstracts.

15 CFR 921.40 - Ongoing oversight and evaluations of designated National Estuarine Research Reserves.

Code of Federal Regulations, 2010 CFR

2010-01-01

... designated National Estuarine Research Reserves. 921.40 Section 921.40 Commerce and Foreign Trade Regulations..., DEPARTMENT OF COMMERCE OCEAN AND COASTAL RESOURCE MANAGEMENT NATIONAL ESTUARINE RESEARCH RESERVE SYSTEM... and evaluations of designated National Estuarine Research Reserves. (a) The Sanctuaries and Reserve...

Contributing Meaning to Research in Developmental Disabilities: Integrating Participatory Action and Methodological Rigor

ERIC Educational Resources Information Center

Powers, Laurie E.

2017-01-01

Action research approaches reflecting power sharing by academic and community researchers, full engagement of community partners across all study phases, and ongoing commitment to partnership and capacity building have been increasingly embraced, particularly in research affecting marginalized populations. Findings suggest action research…

Feature: Post Traumatic Stres Disorder PTSD: NIH Research to Results

MedlinePlus

... including PTSD, persist for those affected by 2005's Hurricane Katrina. This is important because previously researchers found that mental disorders usually decrease and fade after about two years. Ongoing ... Hurricane Ike. Other research is exploring whether certain drugs ...

Terminal Area ATM Research at NASA Ames

NASA Technical Reports Server (NTRS)

Tobias, Leonard

1997-01-01

The presentation will highlight the following: (1) A brief review of ATC research underway 15 years ago; (2) A summary of Terminal Area ATM Tool Development ongoing at NASA Ames; and (3) A projection of research activities 10-15 years from now.

Residency research requirements and the CanMEDS-FM scholar role

PubMed Central

Koo, Jonathan; Bains, Jason; Collins, Marisa B.; Dharamsi, Shafik

2012-01-01

Abstract Objective To explore the perspectives of family medicine residents and recent family medicine graduates on the research requirements and other CanMEDS scholar competencies in family practice residency training. Design Semistructured focus groups and individual interviews. Setting Family practice residency program at the University of British Columbia in Vancouver. Participants Convenience sample of 6 second-year family medicine residents and 6 family physicians who had graduated from the University of British Columbia family practice residency program within the previous 5 years. Methods Two focus groups with residents and individual interviews with each of the 6 recently graduated physicians. All interviews were audiotaped, transcribed, and analyzed for thematic content. Main findings Three themes emerged that captured key issues around research requirements in family practice training: 1) relating the scholar role to family practice, 2) realizing that scholarship is more than simply the creation or discovery of new knowledge, and 3) addressing barriers to integrating research into a clinical career. Conclusion Creation of new medical knowledge is just one aspect of the CanMEDS scholar role, and more attention should be paid to the other competencies, including teaching, enhancing professional activities through ongoing learning, critical appraisal of information, and learning how to better contribute to the dissemination, application, and translation of knowledge. Research is valued as important, but opinions still vary as to whether a formal research study should be required in residency. Completion of residency research projects is viewed as somewhat rewarding, but with an equivocal effect on future research intentions. PMID:22859631

Research in mobile robotics at ORNL/CESAR (Oak Ridge National Laboratory/Center for Engineering Systems Advanced Research)

DOE Office of Scientific and Technical Information (OSTI.GOV)

Mann, R.C.; Weisbin, C.R.; Pin, F.G.

1989-01-01

This paper reviews ongoing and planned research with mobile autonomous robots at the Oak Ridge National Laboratory (ORNL), Center for Engineering Systems Advanced Research (CESAR). Specifically we report on results obtained with the robot HERMIES-IIB in navigation, intelligent sensing, learning, and on-board parallel computing in support of these functions. We briefly summarize an experiment with HERMIES-IIB that demonstrates the capability of smooth transitions between robot autonomy and tele-operation. This experiment results from collaboration among teams at the Universities of Florida, Michigan, Tennessee, and Texas; and ORNL in a program targeted at robotics for advanced nuclear power stations. We conclude bymore » summarizing ongoing R D with our new mobile robot HERMIES-III which is equipped with a seven degree-of-freedom research manipulator arm. 12 refs., 4 figs.« less

On-Going International Research Program on Irradiated Concrete Conducted by DOE, EPRI and Japan Research Institutions. Roadmap, Achievements and Path Forward

DOE Office of Scientific and Technical Information (OSTI.GOV)

Le Pape, Yann; Rosseel, Thomas M.

The Joint Department of Energy (DOE)-Electric Power Research Institute (EPRI) Program (Light Water Reactor Sustainability (LWRS) Program–Material Pathway–Concrete and Long-Term Operation (LTO) Program) and US Nuclear Regulatory Commission (NRC) research studies aim at understanding the most prominent degradation modes and their effects on the long-term operation of concrete structures to nuclear power generation. Based on the results of the Expanded Materials Degradation Analysis (EMDA), (NUREG/CR-7153, ORNL/TM-2011/545), irradiated concrete and alkali-silica reaction (ASR)-affected concrete structures are the two prioritized topics of on-going research. This report focuses specifically on the topic of irradiated concrete and summarizes the main accomplishments obtained by thismore » joint program, but also provides an overview of current relevant activities domestically and internationally. Possible paths forward are also suggested to help near-future orientation of this program.« less

A web-portal for interactive data exploration, visualization, and hypothesis testing

PubMed Central

Bartsch, Hauke; Thompson, Wesley K.; Jernigan, Terry L.; Dale, Anders M.

2014-01-01

Clinical research studies generate data that need to be shared and statistically analyzed by their participating institutions. The distributed nature of research and the different domains involved present major challenges to data sharing, exploration, and visualization. The Data Portal infrastructure was developed to support ongoing research in the areas of neurocognition, imaging, and genetics. Researchers benefit from the integration of data sources across domains, the explicit representation of knowledge from domain experts, and user interfaces providing convenient access to project specific data resources and algorithms. The system provides an interactive approach to statistical analysis, data mining, and hypothesis testing over the lifetime of a study and fulfills a mandate of public sharing by integrating data sharing into a system built for active data exploration. The web-based platform removes barriers for research and supports the ongoing exploration of data. PMID:24723882

Ninth workshop on seedling physiology and growth problems in oak plantings (abstracts)

Treesearch

D.R. Weigel; J.W. Van Sambeek; C.H., eds. Michler

2005-01-01

Research results and ongoing research activities in field performance of oak plantings, seedling propagation, genetics, acorn germination, and natural regeneration of oaks are described in 26 abstracts.

The development of a cancer genetic-specific measure of coping: the GRACE.

PubMed

Phelps, C; Bennett, P; Jones, H; Hood, K; Brain, K; Murray, A

2010-08-01

Generic measures of coping fail to capture the process of undergoing specific health processes such as cancer genetic risk assessment. The Genetic Risk Assessment Coping Evaluation (GRACE) has been developed to provide greater specificity of measurement. Based upon previous research findings, the GRACE measures the degree of stress associated with 11 recognised sources of stress for individuals undergoing the early stages of cancer genetic risk assessment, and the use of up to eight coping strategies they may elicit. This paper reports preliminary data from the piloting of the GRACE within a randomised trial of a coping intervention. Of the 265 participants who completed and returned their baseline questionnaire (prior to being informed of their level of genetic risk), 257 completed the GRACE. The most highly endorsed sources of stress involved concerns relating to family members, endorsed by over 60% of respondents, and concerns about how the participants would cope if found to be at increased risk (59%). Participants made use of multiple coping strategies across different sources of stress. The most frequently reported coping strategies were emotion-focused, which may reflect the stage of the assessment process. The completion rates for the matrix and specificity of responses provided suggest that the GRACE may be an acceptable measurement tool. Further data collection and validation is ongoing. (c) 2009 John Wiley & Sons, Ltd.

The Ethical, Legal, and Social Implications Program of the National Human Genome Research Institute: reflections on an ongoing experiment.

PubMed

McEwen, Jean E; Boyer, Joy T; Sun, Kathie Y; Rothenberg, Karen H; Lockhart, Nicole C; Guyer, Mark S

2014-01-01

For more than 20 years, the Ethical, Legal, and Social Implications (ELSI) Program of the National Human Genome Research Institute has supported empirical and conceptual research to anticipate and address the ethical, legal, and social implications of genomics. As a component of the agency that funds much of the underlying science, the program has always been an experiment. The ever-expanding number of issues the program addresses and the relatively low level of commitment on the part of other funding agencies to support such research make setting priorities especially challenging. Program-supported studies have had a significant impact on the conduct of genomics research, the implementation of genomic medicine, and broader public policies. The program's influence is likely to grow as ELSI research, genomics research, and policy development activities become increasingly integrated. Achieving the benefits of increased integration while preserving the autonomy, objectivity, and intellectual independence of ELSI investigators presents ongoing challenges and new opportunities.

Polish forensic medicine A.D. 2016 - report of the National Consultant.

PubMed

Teresiński, Grzegorz

2016-01-01

The aim of the study was to present the current state and basis of functioning of an academic model of forensic expert activities in Poland and perspectives of their further development. The study material included information obtained from a preliminary survey among regional consultants within the ongoing activities of the national consultant team. The recently completed period of research infrastructure support within the policy of coherence of the European Union contributed to significant advances in scientific-educational potential of the majority of university forensic medicine centres. However, the improved educational base and purchases of new diagnostic devices were not associated with a considerable increase in staff resources of individual units, which finally decides about the renown of the entire discipline. It is necessary to undertake initiatives to highlight the importance of forensic medicine as a separate medical field and to increase the number of physicians starting specialist trainings. A highly profiled nature of the speciality necessitates cooperation with other centres and receptiveness to clinical fields. The establishment of various forms of cooperation is a measure of optimal use of equipment and stimulation of multi-centre research.

[Randomized, controlled clinical trials with observational follow-up investigations for evaluating efficacy of antihyperglycaemic treatment. II. Features of and lessons from the follow-up investigations].

PubMed

Jermendy, György

2018-04-01

Although the outcomes of the follow-up investigation period of the randomized clinical studies for evaluating the efficacy of a treatment or an antidiabetic drug may be confounded or potentially biased by several factors, the results are widely accepted by the diabetes community. In line with the theory of metabolic memory or metabolic legacy, early and intensive antihyperglycaemic treatment should be provided for all diabetic patients as this strategy can result in beneficial effects even in the long run. The recent cardiovascular safety trials with new, innovative antidiabetic drugs differ in several aspects from the former efficacy studies. Ten cardiovascular safety trials were completed so far enabling to define their unique and common features. It can be anticipated that the era of randomized, controlled efficacy studies with observational follow-up investigations came to an end in diabetes research. Nowadays, cardiovascular safety trials are in the focus of clinical research in diabetology and results of several ongoing studies are expected with interest in the near future. Orv Hetil. 2018; 159(16): 615-619.

Sustainable urban stormwater management in the tropics: An evaluation of Singapore's ABC Waters Program

NASA Astrophysics Data System (ADS)

Lim, H. S.; Lu, X. X.

2016-07-01

The Active Beautiful Clean (ABC) Waters Program was implemented in 2006 as part of Singapore's stormwater management strategy and reflects the country's move towards Water Sensitive Urbanism through the adoption of Low-Impact Development (LID) ideology and practices. It is the first holistic and comprehensive LID program in the tropics and holds promise for extension to other tropical cities. This paper presents a comprehensive summary of the goals, LID practices (ABC design features) and design considerations as well as results of several monitored sites, including a constructed wetland, two rain gardens, green roofs and three canal restoration projects. We evaluate the ABC Waters Program based on these initial results and consider the challenges, issues and the research needs for it to meet its hydrological and water quality remediation goals. So far, the ABC design features evaluated perform well in removing particulates. Performance in nutrient removal is poor. With over 60 projects completed within 10 years, post-project monitoring and evaluation is necessary and complements on-going laboratory and modelling research projects conducted by local academic institutions.

Optimal clinical management of children receiving dietary therapies for epilepsy: Updated recommendations of the International Ketogenic Diet Study Group.

PubMed

Kossoff, Eric H; Zupec-Kania, Beth A; Auvin, Stéphane; Ballaban-Gil, Karen R; Christina Bergqvist, A G; Blackford, Robyn; Buchhalter, Jeffrey R; Caraballo, Roberto H; Cross, J Helen; Dahlin, Maria G; Donner, Elizabeth J; Guzel, Orkide; Jehle, Rana S; Klepper, Joerg; Kang, Hoon-Chul; Lambrechts, Danielle A; Liu, Y M Christiana; Nathan, Janak K; Nordli, Douglas R; Pfeifer, Heidi H; Rho, Jong M; Scheffer, Ingrid E; Sharma, Suvasini; Stafstrom, Carl E; Thiele, Elizabeth A; Turner, Zahava; Vaccarezza, Maria M; van der Louw, Elles J T M; Veggiotti, Pierangelo; Wheless, James W; Wirrell, Elaine C

2018-06-01

Ketogenic dietary therapies (KDTs) are established, effective nonpharmacologic treatments for intractable childhood epilepsy. For many years KDTs were implemented differently throughout the world due to lack of consistent protocols. In 2009, an expert consensus guideline for the management of children on KDT was published, focusing on topics of patient selection, pre-KDT counseling and evaluation, diet choice and attributes, implementation, supplementation, follow-up, side events, and KDT discontinuation. It has been helpful in outlining a state-of-the-art protocol, standardizing KDT for multicenter clinical trials, and identifying areas of controversy and uncertainty for future research. Now one decade later, the organizers and authors of this guideline present a revised version with additional authors, in order to include recent research, especially regarding other dietary treatments, clarifying indications for use, side effects during initiation and ongoing use, value of supplements, and methods of KDT discontinuation. In addition, authors completed a survey of their institution's practices, which was compared to responses from the original consensus survey, to show trends in management over the last 10 years.

Motivation for change as a predictor of treatment response for dysthymia.

PubMed

Frías Ibáñez, Álvaro; González Vallespí, Laura; Palma Sevillano, Carol; Farriols Hernando, Núria

2016-05-01

Dysthymia constitutes a chronic, mild affective disorder characterized by heterogeneous treatment effects. Several predictors of clinical response and attendance have been postulated, although research on the role of the psychological variables involved in this mental disorder is still scarce. Fifty-four adult patients, who met criteria for dysthymia completed an ongoing naturalistic treatment based on the brief interpersonal psychotherapy (IPT-B), which was delivered bimonthly over 16 months. As potential predictor variables, the therapeutic alliance, coping strategies, perceived self-efficacy, and motivation for change were measured at baseline. Outcome variables were response to treatment (Clinical Global Impression and Beck’s Depression Inventory) and treatment attendance. Stepwise multiple linear regression analyses revealed that higher motivation for change predicted better response to treatment. Moreover, higher motivation for change also predicted treatment attendance. Therapeutic alliance was not a predictor variable of neither clinical response nor treatment attendance. These preliminary findings support the adjunctive use of motivational interviewing (MI) techniques in the treatment of dysthymia. Further research with larger sample size and follow-up assessment is warranted.

Green utilities for research and eco-tourist communities, Rio Bravo, Belize, Central America

DOE Office of Scientific and Technical Information (OSTI.GOV)

Jackson, O.

1997-12-31

Programme for Belize (PFB), a non-governmental organization which owns and manages the Rio Bravo Conservation and Management Area (RBCMA), a 229,000 acre section of subtropical rainforest in northwestern Belize, is developing a series of research and eco-tourism developments as sustainable development projects. Guided by a comprehensive Sustainable Infrastructure Plan completed by Caribbean Infra-Tech, Inc. (CIT) in 1995, PFB adopted an organizational goal of implementing 100% green renewable energy-based utilities for their two major development sites: La Milpa and Hill Bank stations. To date, PFB has constructed or installed over 20 kW of standalone PV power, sustainable water supply systems, recyclingmore » waste treatment systems, and a model sustainable Dormitory and Bath House facility in the RBCMA. In addition, a Resource Conservation and Management Program (RCMP), which is to guide ongoing visitor orientation, staff training, and sustainable systems operations and maintenance, is now being prepared for immediate implementation. In this paper, the design and technical performance of the solar (PV) electric power plants, PV water pumping, solar water heating and other green utility systems will be assessed.« less

ISS Training Best Practices and Lessons Learned

NASA Technical Reports Server (NTRS)

Barshi, Immanuel; Dempsey, Donna L.

2017-01-01

Training our crew members for long duration exploration-class missions (LDEM) will have to be qualitatively and quantitatively different from current training practices. However, there is much to be learned from the extensive experience NASA has gained in training crew members for missions on board the International Space Station (ISS). Furthermore, the operational experience on board the ISS provides valuable feedback concerning training effectiveness. Keeping in mind the vast differences between current ISS crew training and training for LDEM, the needs of future crew members, and the demands of future missions, this ongoing study seeks to document current training practices and lessons learned. The goal of the study is to provide input to the design of future crew training that takes as much advantage as possible of what has already been learned and avoids as much as possible past inefficiencies. Results from this study will be presented upon its completion. By researching established training principles, examining future needs, and by using current practices in spaceflight training as test beds, this research project is mitigating program risks and generating templates and requirements to meet future training needs.

ISS Training Best Practices and Lessons Learned

NASA Technical Reports Server (NTRS)

Dempsey, Donna L.; Barshi, Immanuel

2018-01-01

Training our crew members for long-duration Deep Space Transport (DST) missions will have to be qualitatively and quantitatively different from current training practices. However, there is much to be learned from the extensive experience NASA has gained in training crew members for missions on board the International Space Station (ISS). Furthermore, the operational experience on board the ISS provides valuable feedback concerning training effectiveness. Keeping in mind the vast differences between current ISS crew training and training for DST missions, the needs of future crew members, and the demands of future missions, this ongoing study seeks to document current training practices and lessons learned. The goal of the study is to provide input to the design of future crew training that takes as much advantage as possible of what has already been learned and avoids as much as possible past inefficiencies. Results from this study will be presented upon its completion. By researching established training principles, examining future needs, and by using current practices in spaceflight training as test beds, this research project is mitigating program risks and generating templates and requirements to meet future training needs.

Next Generation Remote Agent Planner

NASA Technical Reports Server (NTRS)

Jonsson, Ari K.; Muscettola, Nicola; Morris, Paul H.; Rajan, Kanna

1999-01-01

In May 1999, as part of a unique technology validation experiment onboard the Deep Space One spacecraft, the Remote Agent became the first complete autonomous spacecraft control architecture to run as flight software onboard an active spacecraft. As one of the three components of the architecture, the Remote Agent Planner had the task of laying out the course of action to be taken, which included activities such as turning, thrusting, data gathering, and communicating. Building on the successful approach developed for the Remote Agent Planner, the Next Generation Remote Agent Planner is a completely redesigned and reimplemented version of the planner. The new system provides all the key capabilities of the original planner, while adding functionality, improving performance and providing a modular and extendible implementation. The goal of this ongoing project is to develop a system that provides both a basis for future applications and a framework for further research in the area of autonomous planning for spacecraft. In this article, we present an introductory overview of the Next Generation Remote Agent Planner. We present a new and simplified definition of the planning problem, describe the basics of the planning process, lay out the new system design and examine the functionality of the core reasoning module.

CoMET: Cost and Mass Evaluation Tool for Spacecraft and Mission Design

NASA Technical Reports Server (NTRS)

Bieber, Ben S.

2005-01-01

New technology in space exploration is often developed without a complete knowledge of its impact. While the immediate benefits of a new technology are obvious, it is harder to understand its indirect consequences, which ripple through the entire system. COMET is a technology evaluation tool designed to illuminate how specific technology choices affect a mission at each system level. COMET uses simplified models for mass, power, and cost to analyze performance parameters of technologies of interest. The sensitivity analysis that CoMET provides shows whether developing a certain technology will greatly benefit the project or not. CoMET is an ongoing project approaching a web-based implementation phase. This year, development focused on the models for planetary daughter craft, such as atmospheric probes, blimps and balloons, and landers. These models are developed through research into historical data, well established rules of thumb, and engineering judgment of experts at JPL. The model is validated by corroboration with JpL advanced mission studies. Other enhancements to COMET include adding launch vehicle analysis and integrating an updated cost model. When completed, COMET will allow technological development to be focused on areas that will most drastically improve spacecraft performance.

The Convergent and Divergent Validity of the Vanderbilt Assessment of Leadership in Education (VAL-ED): Instructional Leadership and Emotional Intelligence

ERIC Educational Resources Information Center

Goldring, Ellen; Cravens, Xiu; Porter, Andrew; Murphy, Joseph; Elliott, Steve

2015-01-01

Purpose: The purpose of this paper is to contribute to the ongoing dialog of whether and how instructional leadership is distinguished conceptually from general leadership notions, such as charisma, and to continue the ongoing psychometric research on the The Vanderbilt Assessment of Leadership in Education (VAL-ED) by examining its convergent and…

Ongoing Progress in Spacecraft Controls

NASA Technical Reports Server (NTRS)

Ghosh, Dave (Editor)

1992-01-01

This publication is a collection of papers presented at the Mars Mission Research Center workshop on Ongoing Progress in Spacecraft Controls. The technical program addressed additional Mars mission control problems that currently exist in robotic missions in addition to human missions. Topics include control systems design in the presence of large time delays, fuel-optimal propulsive control, and adaptive control to handle a variety of unknown conditions.

NGEE Arctic Plant Traits: Soil Depth, Kougarok Road Mile Marker 64, Seward Peninsula, Alaska, Beginning 2016

DOE Data Explorer

Stel, Holly Vander; Wullschleger, Stan; Breen, Amy; Iversen, Colleen

2017-03-01

Data includes active layer depth measured at intensive plots, reference points, vegetation plots, and soil temperature/moisture monitoring stations at the Kougarok hill slope located at Kougarok Road, Mile Marker 64. Data collection started July 2016 and will be ongoing. Data upload will be completed January 2017.

Developing a prediction model for Armillaria solidipes in Arizona

Treesearch

N. B. Klopfenstein; J. W Hanna; M. L. Fairweather; J. D. Shaw; R. Mathiasen; C. Hoffman; E. Nelson; M. -S. Kim; A. L. Ross-Davis

2012-01-01

In 2010, a collaborative project was started to determine the distribution of Armillaria solidipes (= A. ostoyae) in Arizona. The methods and preliminary accomplishments of the 2010 and 2011 (ongoing) field surveys/collections are summarized. During the next phase of this project, surveys will be completed and remaining Armillaria isolates will be identified using DNA-...

Student Experiences at Off-Campus Parties: Results from a Multicampus Survey

ERIC Educational Resources Information Center

Jakeman, Rick C.; Silver, Blake R.; Molasso, William

2014-01-01

The need to understand the settings in which students drink represents an ongoing challenge for universities. Undergraduate students (N = 2,146) completed an online multicampus survey to capture the perceptions of off-campus party guests regarding common party behaviors and events. Results indicate that students frequently attend off-campus…

Finishing High School: Alternative Pathways and Dropout Recovery

ERIC Educational Resources Information Center

Tyler, John H.; Lofstrom, Magnus

2009-01-01

John Tyler and Magnus Lofstrom take a close look at the problems posed when students do not complete high school. The authors begin by discussing the ongoing, sometimes heated, debate over how prevalent the dropout problem is. They note that one important reason for discrepancies in reported dropout rates is whether holders of the General…

A Dynamic Capabilities View of Employability: Exploring the Drivers of Competitive Advantage for University Graduates

ERIC Educational Resources Information Center

Finch, David J.; Peacock, Melanie; Levallet, Nadege; Foster, William

2016-01-01

Purpose: The increasing demand for post-secondary education, and the ongoing difficulty students' face in securing appropriate work upon program completion, highlight the importance of an enhanced understanding of employability resources for university graduates. Just as organizations achieve a strategic advantage from resources and dynamic…

The Complexities of Digital Storytelling: Factors Affecting Performance, Production, and Project Completion

ERIC Educational Resources Information Center

Gobel, Peter; Kano, Makimi

2016-01-01

Digital storytelling projects provide a variety of opportunities for learning in the language classroom, but along with these opportunities come a number of challenges for both pedagogy and technology. This presentation describes an ongoing multi-method study into factors involved in task-based learning using digital storytelling. Using intact…

Doctoral Success as Ongoing Quality Business: A Possible Conceptual Framework

ERIC Educational Resources Information Center

Bitzer, E. M.

2011-01-01

The challenges involving doctoral non-completion and a lack of academic or scholarly quality are not restricted to putting the blame on doctoral candidates themselves, their supervisors or the institutions where they enrol. As candidates carry huge responsibilities when entering doctoral studies, success can be associated with an array of factors…

76 FR 15028 - Airport Improvement Program (AIP): Interim Policy Regarding Access to Airports From Residential...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-18

... resolution. The goal of the interim policy is to strike a careful balance by accommodating residential... will allow the agency to complete a separate, ongoing general aviation airport study that is analyzing the federally assisted general aviation airport system. The interim policy adopts the changes proposed...

Group Adlerian Play Therapy with Children with Off-Task Behaviors

ERIC Educational Resources Information Center

Meany-Walen, Kristin K.; Bullis, Quinn; Kottman, Terry; Dillman Taylor, Dalena

2015-01-01

Children who are off-task in schools struggle with completing their work and engage in disruptive behaviors. Without intervention, these behaviors tend to worsen, putting them at risk for more serious, ongoing problems throughout life. Group counseling provides opportunities for people to practice socially useful behaviors. Using a single case…

The Multiple Challenges of Multimedia: Development, Implementation, and Evaluation.

ERIC Educational Resources Information Center

Kassen, Margaret Ann

1998-01-01

This article presents an overview of an ongoing initiative to develop, integrate, and evaluate multimedia lessons to enhance listening comprehension in Spanish language classes at the Catholic University of America (District of Columbia). Focusing on the process involved, the two phases of the project that have been completed are examined,…

Classification of Innovation Objectives Set for Continuing Professional Teacher Development

ERIC Educational Resources Information Center

Tyunnikov, Yurii S.

2017-01-01

The present demand for teachers, showing advanced aptitude for innovations, is an important reason for promotion of innovative practices in the continuous teacher training. For the on-going development of a continuous training system preparing teachers for innovative activities, it is necessary to have a complete taxonomy of practical objectives.…

International Multidisciplinary Learning: An Account of a Collaborative Effort among Three Higher Education Institutions

ERIC Educational Resources Information Center

Poh, Paul S. H.; Soetanto, Robby; Austin, Stephen; Adamu, Zulkifar A.

2014-01-01

Requiring students to complete their course assignments in partnership and in collaboration with students from other institutions is not commonplace teaching pedagogy. Even less so when they transcend disciplines and international borders. This paper presents a brief account of an ongoing collaborative effort between Ryerson University, Coventry…

Traumatic Stress Symptoms and Breast Cancer: The Role of Childhood Abuse

ERIC Educational Resources Information Center

Goldsmith, Rachel E.; Jandorf, Lina; Valdimarsdottir, Heiddis; Amend, Kandace L.; Stoudt, Brett G.; Rini, Christine; Hershman, Dawn; Neugut, Alfred; Reilly, James J.; Tartter, Paul I.; Feldman, Sheldon M.; Ambrosone, Christine B.; Bovbjerg, Dana H.

2010-01-01

Objective: The present study investigated relations between reported childhood abuse and recent traumatic stress symptoms in women newly diagnosed with breast cancer (n = 330). Methods: As part of a larger ongoing study, patients from eight public and private hospitals were referred by their physicians and completed the Childhood Trauma…

Latino/a Students and Faculty Interaction: Las Voces De Persistencia

ERIC Educational Resources Information Center

Hampton, Joyce L.

2010-01-01

Latinos consistently have the lowest degree completion rate throughout the United States (Kurlaender & Flores, 2005). At the same time, Latinos are the fastest growing sector of the U.S. population. Taken together, these facts demonstrate an ongoing and growing inequity in educational opportunities and outcomes for a significant portion of the…

Cord-Blood Banking

MedlinePlus

... cord blood mainly because of the promise that stem cell research holds for the future. Most of us would have little use for stem cells now, but research into using them to treat diseases is ongoing — ...

Fifth workshop on seedling physiology and growth problems in oak plantings (abstracts).

Treesearch

Janette R. Thompson; Richard C. Schultz; J.W. Van Sambeek

1993-01-01

Research results and ongoing research activities in field performance of planted trees, seedling propagation, physiology, genetics, acorn germination, and natural regeneration for oaks are described in 30 abstracts.

IRIS and the National Research Council (NRC)

EPA Pesticide Factsheets

Since the 2011 National Academies’ National Research Council (NRC) review of the IRIS Program's assessment of Formaldehyde, EPA and NRC have had an ongoing relationship into the improvements of developing the IRIS Assessments.

Mechanisms and Effects of Transcranial Direct Current Stimulation

PubMed Central

Giordano, James; Bikson, Marom; Kappenman, Emily S.; Clark, Vincent P.; Coslett, H. Branch; Hamblin, Michael R.; Hamilton, Roy; Jankord, Ryan; Kozumbo, Walter J.; McKinley, R. Andrew; Nitsche, Michael A.; Reilly, J. Patrick; Richardson, Jessica; Wurzman, Rachel

2017-01-01

The US Air Force Office of Scientific Research convened a meeting of researchers in the fields of neuroscience, psychology, engineering, and medicine to discuss most pressing issues facing ongoing research in the field of transcranial direct current stimulation (tDCS) and related techniques. In this study, we present opinions prepared by participants of the meeting, focusing on the most promising areas of research, immediate and future goals for the field, and the potential for hormesis theory to inform tDCS research. Scientific, medical, and ethical considerations support the ongoing testing of tDCS in healthy and clinical populations, provided best protocols are used to maximize safety. Notwithstanding the need for ongoing research, promising applications include enhancing vigilance/attention in healthy volunteers, which can accelerate training and support learning. Commonly, tDCS is used as an adjunct to training/rehabilitation tasks with the goal of leftward shift in the learning/treatment effect curves. Although trials are encouraging, elucidating the basic mechanisms of tDCS will accelerate validation and adoption. To this end, biomarkers (eg, clinical neuroimaging and findings from animal models) can support hypotheses linking neurobiological mechanisms and behavioral effects. Dosage can be optimized using computational models of current flow and understanding dose–response. Both biomarkers and dosimetry should guide individualized interventions with the goal of reducing variability. Insights from other applied energy domains, including ionizing radiation, transcranial magnetic stimulation, and low-level laser (light) therapy, can be prudently leveraged. PMID:28210202

Nondestructive testing and evaluation of wood : a worldwide research update

Treesearch

Brian K. Brashaw; Voichita Bucur; Ferenc Divos; Raquel Goncalves; Jianxiong Lu; Roger Meder; Roy F. Pellerin; Simon Potter; Robert J Ross; Xiping Wang; Yafang Yin

2009-01-01

The international forest products research community is responding to these driving forces by conducting NDT/NDE research to provide the technologies needed to address these challenges. This article presents a sample of the on-going NDT/NDE research efforts being conducted in several areas of the world.

The Golden Gate: Building Bridges Between Research and Operations

NASA Technical Reports Server (NTRS)

Schmidt, Lacey L.

2010-01-01

Previous research has discussed the ongoing dilemma of implementing research-based findings in an applied setting. This panel will discuss lessons learned from various examples where bridges have been forged between research and operations, and examine ways to promote and achieve similar collaborations in other areas in the future.

78 FR 20637 - Notification of Public Meeting and a Public Teleconference of the Hydraulic Fracturing Research...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-04-05

... on EPA's ongoing research on the potential impacts of hydraulic fracturing on drinking water... Teleconference of the Hydraulic Fracturing Research Advisory Panel AGENCY: Environmental Protection Agency (EPA... Office announces a public meeting and public teleconference of the Hydraulic Fracturing Research Advisory...

iNACOL Research Agenda

ERIC Educational Resources Information Center

International Association for K-12 Online Learning, 2013

2013-01-01

The International Association for K-12 Online Learning (iNACOL) publishes a research agenda on an ongoing basis to continue its work in field-building, capacity-building and knowledge-building. Based on a 2013 survey of the field to identify research needs, iNACOL developed a research approach, including the following: (1) Build a collaborative…

Activist Research and Organizing: Blurring the Boundaries, Challenging the Binaries

ERIC Educational Resources Information Center

Choudry, Aziz

2014-01-01

This article draws from ongoing research into the practices and processes of activist researchers. It discusses social relations of knowledge production located outside of academia with/in social movement milieus. Focusing on the politics of research in people's organizations and social movement organizations in the Philippines, it builds on…

Trials advance low-salinity culture of Cobia, Pompano, and other species

USDA-ARS?s Scientific Manuscript database

An ongoing collaborative research effort between scientists of the USDA Agricultural Research Service and aquaculture researchers of the Harbor Branch Oceanographic Institute at Florida Atlantic University to develop technologies for rearing fish in low salinity recirculating aquaculture systems is ...

Financial Analysis for R&D Decisions.

ERIC Educational Resources Information Center

Carter, Robert

1997-01-01

Using personal computer spreadsheet software, standard corporate financial analysis can help university research administrators communicate the value of research and development to sponsors and other stakeholders; balance projects, technologies, or categories of research; and continually assess the value of investing in ongoing projects. It also…

Directions in Near-Death Research.

ERIC Educational Resources Information Center

Lundahl, C.R.

1981-01-01

Explains that near-death research is moving in three directions: (1) the ongoing accumulation of knowledge on the near-death experience through scientifically derived studies; (2) the examination of post-mortem survival; and (3) the clinical application of the findings of near- death research. (Author/RC)

Does playing video games improve laparoscopic skills?

PubMed

Ou, Yanwen; McGlone, Emma Rose; Camm, Christian Fielder; Khan, Omar A

2013-01-01

A best evidence topic in surgery was written according to a structured protocol. The question addressed was whether playing video games improves surgical performance in laparoscopic procedures. Altogether 142 papers were found using the reported search, of which seven represented the best evidence to answer the clinical question. The details of the papers were tabulated including relevant outcomes and study weaknesses. We conclude that medical students and experienced laparoscopic surgeons with ongoing video game experience have superior laparoscopic skills for simulated tasks in terms of time to completion, improved efficiency and fewer errors when compared to non-gaming counterparts. There is some evidence that this may be due to better psycho-motor skills in gamers, however further research would be useful to demonstrate whether there is a direct transfer of skills from laparoscopic simulators to the operating table. Copyright © 2013 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

Production of Renewable Natural Gas from Waste Biomass

NASA Astrophysics Data System (ADS)

Kumar, Sachin; Suresh, S.; Arisutha, S.

2013-03-01

Biomass energy is expected to make a major contribution to the replacement of fossil fuels. Methane produced from biomass is referred to as bio-methane, green gas, bio-substitute natural gas or renewable natural gas (RNG) when it is used as a transport fuel. Research on upgrading of the cleaned producer gas to RNG is still ongoing. The present study deals with the conversion of woody biomass into fuels, RNG using gasifier. The various effects of parameters like temperature, pressure, and tar formation on conversion were also studied. The complete carbon conversion was observed at 480 °C and tar yield was significantly less. When biomass was gasified with and without catalyst at about 28 s residence time, ~75 % (w/w) and 88 % (w/w) carbon conversion for without and with catalyst was observed. The interest in RNG is growing; several initiatives to demonstrate the thermal-chemical conversion of biomass into methane and/or RNG are under development.

Transmission Parameters of the 2001 Foot and Mouth Epidemic in Great Britain

PubMed Central

Chis Ster, Irina; Ferguson, Neil M.

2007-01-01

Despite intensive ongoing research, key aspects of the spatial-temporal evolution of the 2001 foot and mouth disease (FMD) epidemic in Great Britain (GB) remain unexplained. Here we develop a Markov Chain Monte Carlo (MCMC) method for estimating epidemiological parameters of the 2001 outbreak for a range of simple transmission models. We make the simplifying assumption that infectious farms were completely observed in 2001, equivalent to assuming that farms that were proactively culled but not diagnosed with FMD were not infectious, even if some were infected. We estimate how transmission parameters varied through time, highlighting the impact of the control measures on the progression of the epidemic. We demonstrate statistically significant evidence for assortative contact patterns between animals of the same species. Predictive risk maps of the transmission potential in different geographic areas of GB are presented for the fitted models. PMID:17551582

Inconel 690 is alloy of choice for steam-generator tubing

DOE Office of Scientific and Technical Information (OSTI.GOV)

Strauss, S.D.

1996-02-01

The product of two decades of research and plant application, Inconel 690 promises superior long-term resistance to tube cracking in comparison to alloy 600. Ongoing steam-generator management techniques applied at nuclear pressurized-water-reactor (PWR) plants focus on tube monitoring, inspection, and repair, and on water-chemistry control. Of greatest concern to owner/operators of steam generators (SGs) with recirculating (U-bend) rather than straight through tubes is corrosion of several forms, including pitting, thinning, and cracking. As problems persist and operating and maintenance (O and M) costs become prohibitive, managers must consider the remaining option: complete or partial SG replacement. Although replacement costs canmore » range upward of $100-million, this step restores full-power operation, simplifies inspection, shortens subsequent outages, increases unit availability, and reduces radiation exposure of maintenance personnel. Taken together, these can lead to economies over the long term.« less

Design of the Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial.

PubMed

Bradford, Andrew; Lees, Kennedy

2000-01-01

The Intravenous Magnesium Efficacy in Acute Stroke (IMAGES) trial is a multicentre,randomised, placebo-controlled trial of magnesium sulphate (MgSO4) funded by the UK Medical Research Council. When complete, it will be the largest single neuroprotective study undertaken to date. Conscious patients presenting within 12 h of acute stroke with limb weakness are eligible. The primary outcome measure is combined death and disability as measured using the Barthel Index at 90-day follow up. By randomizing 2700 patients, the study will have 84% power to detect a 5.5% absolute reduction in the primary end-point. By April 2000, 86 centres were participating, with representation in Canada, USA, Europe, South America, Singapore and Australia. So far, 1206 patients have been randomised, of whom 37% were treated within 6 h. Overall 3-month mortality was 20% and the primary outcome event rate was 43%. The study is ongoing and centres worldwide are encouraged to participate.

Exposure to Acute Stress is Associated with Attenuated Sweet Taste

PubMed Central

al’Absi, Mustafa; Nakajima, Motohiro; Hooker, Stephanie; Wittmers, Larry; Cragin, Tiffany

2011-01-01

This study examined the effects of stress on taste perception. Participants (N = 38; 21 women) completed two laboratory sessions: one stress (public speaking, math, and cold pressor) and one control rest session. The taste perception test was conducted at the end of each session and included rating the intensity and pleasantness of sweet, salty, sour, and savory solutions at suprathreshold concentrations. Cardiovascular, hormonal, and mood measures were collected throughout the sessions. Participants showed the expected changes in cardiovascular, hormonal, and mood measures in response to stress. Reported intensity of the sweet solution was significantly lower on the stress day than on the rest day. Cortisol level post stress predicted reduced intensity of salt and sour, suggesting that stress-related changes in adrenocortical activity were related to reduced taste intensity. Results indicate that acute stress may alter taste perception, and ongoing research investigates the extent to which these changes mediate effects of stress on appetite. PMID:22091733

Phytochemicals modulate carcinogenic signaling pathways in breast and hormone-related cancers

PubMed Central

Cojocneanu Petric, Roxana; Braicu, Cornelia; Raduly, Lajos; Zanoaga, Oana; Dragos, Nicolae; Monroig, Paloma; Dumitrascu, Dan; Berindan-Neagoe, Ioana

2015-01-01

Over the years, nutrition and environmental factors have been demonstrated to influence human health, specifically cancer. Owing to the fact that cancer is a leading cause of death worldwide, efforts are being made to elucidate molecular mechanisms that trigger or delay carcinogenesis. Phytochemicals, in particular, have been shown to modulate oncogenic processes through their antioxidant and anti-inflammatory activities and their ability to mimic the chemical structure and activity of hormones. These compounds can act not only by influencing oncogenic proteins, but also by modulating noncoding RNAs such as microRNAs and long noncoding RNAs. Although we are only beginning to understand the complete effects of many natural compounds, such as phytochemicals, researchers are motivated to combine these agents with traditional, chemo-based, or hormone-based therapies to fight against cancer. Since ongoing studies continue to prove effective, herein we exalt the importance of improving dietary choices as a chemo-preventive strategy. PMID:26273208

Development of a Modular Research Platform to Create Medical Observational Studies for Mobile Devices.

PubMed

Zens, Martin; Grotejohann, Birgit; Tassoni, Adrian; Duttenhoefer, Fabian; Südkamp, Norbert P; Niemeyer, Philipp

2017-05-23

Observational studies have proven to be a valuable resource in medical research, especially when performed on a large scale. Recently, mobile device-based observational studies have been discovered by an increasing number of researchers as a promising new source of information. However, the development and deployment of app-based studies is not trivial and requires profound programming skills. The aim of this project was to develop a modular online research platform that allows researchers to create medical studies for mobile devices without extensive programming skills. The platform approach for a modular research platform consists of three major components. A Web-based platform forms the researchers' main workplace. This platform communicates via a shared database with a platform independent mobile app. Furthermore, a separate Web-based login platform for physicians and other health care professionals is outlined and completes the concept. A prototype of the research platform has been developed and is currently in beta testing. Simple questionnaire studies can be created within minutes and published for testing purposes. Screenshots of an example study are provided, and the general working principle is displayed. In this project, we have created a basis for a novel research platform. The necessity and implications of a modular approach were displayed and an outline for future development given. International researchers are invited and encouraged to participate in this ongoing project. ©Martin Zens, Birgit Grotejohann, Adrian Tassoni, Fabian Duttenhoefer, Norbert P Südkamp, Philipp Niemeyer. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 23.05.2017.

Networking among young global health researchers through an intensive training approach: a mixed methods exploratory study

PubMed Central

2014-01-01

Background Networks are increasingly regarded as essential in health research aimed at influencing practice and policies. Less research has focused on the role networking can play in researchers’ careers and its broader impacts on capacity strengthening in health research. We used the Canadian Coalition for Global Health Research (CCGHR) annual Summer Institute for New Global Health Researchers (SIs) as an opportunity to explore networking among new global health researchers. Methods A mixed-methods exploratory study was conducted among SI alumni and facilitators who had participated in at least one SI between 2004 and 2010. Alumni and facilitators completed an online short questionnaire, and a subset participated in an in-depth interview. Thematic analysis of the qualitative data was triangulated with quantitative results and CCGHR reports on SIs. Synthesis occurred through the development of a process model relevant to networking through the SIs. Results Through networking at the SIs, participants experienced decreased isolation and strengthened working relationships. Participants accessed new knowledge, opportunities, and resources through networking during the SI. Post-SI, participants reported ongoing contact and collaboration, although most participants desired more opportunities for interaction. They made suggestions for structural supports to networking among new global health researchers. Conclusions Networking at the SI contributed positively to opportunities for individuals, and contributed to the formation of a network of global health researchers. Intentional inclusion of networking in health research capacity strengthening initiatives, with supportive resources and infrastructure could create dynamic, sustainable networks accessible to global health researchers around the world. PMID:24460819

Cloudy with a Chance of Pain: Engagement and Subsequent Attrition of Daily Data Entry in a Smartphone Pilot Study Tracking Weather, Disease Severity, and Physical Activity in Patients With Rheumatoid Arthritis.

PubMed

Reade, Samuel; Spencer, Karen; Sergeant, Jamie C; Sperrin, Matthew; Schultz, David M; Ainsworth, John; Lakshminarayana, Rashmi; Hellman, Bruce; James, Ben; McBeth, John; Sanders, Caroline; Dixon, William G

2017-03-24

The increasing ownership of smartphones provides major opportunities for epidemiological research through self-reported and passively collected data. This pilot study aimed to codesign a smartphone app to assess associations between weather and joint pain in patients with rheumatoid arthritis (RA) and to study the success of daily self-reported data entry over a 60-day period and the enablers of and barriers to data collection. A patient and public involvement group (n=5) and 2 focus groups of patients with RA (n=9) supported the codesign of the app collecting self-reported symptoms. A separate "capture app" was designed to collect global positioning system (GPS) and continuous raw accelerometer data, with the GPS-linking providing local weather data. A total of 20 patients with RA were then recruited to collect daily data for 60 days, with entry and exit interviews. Of these, 17 were loaned an Android smartphone, whereas 3 used their own Android smartphones. Of the 20 patients, 6 (30%) withdrew from the study: 4 because of technical challenges and 2 for health reasons. The mean completion of daily entries was 68% over 2 months. Patients entered data at least five times per week 65% of the time. Reasons for successful engagement included a simple graphical user interface, automated reminders, visualization of data, and eagerness to contribute to this easily understood research question. The main barrier to continuing engagement was impaired battery life due to the accelerometer data capture app. For some, successful engagement required ongoing support in using the smartphones. This successful pilot study has demonstrated that daily data collection using smartphones for health research is feasible and achievable with high levels of ongoing engagement over 2 months. This result opens important opportunities for large-scale longitudinal epidemiological research. ©Samuel Reade, Karen Spencer, Jamie C Sergeant, Matthew Sperrin, David M Schultz, John Ainsworth, Rashmi Lakshminarayana, Bruce Hellman, Ben James, John McBeth, Caroline Sanders, William G Dixon. Originally published in JMIR Mhealth and Uhealth (http://mhealth.jmir.org), 24.03.2017.

METAL PARTITIONING IN COMBUSTION PROCESSES

EPA Science Inventory

This article summarizes ongoing research efforts at the National Risk Management Research Laboratory of the U.S. Environmental Protection Agency examining [high temperature] metal behavior within combustion environments. The partitioning of non-volatile (Cr and Ni), semi-volatil...

NASA/MSFC FY-81 Atmospheric Processes Research Review

NASA Technical Reports Server (NTRS)

Turner, R. E. (Compiler)

1981-01-01

Progress in ongoing research programs and future plans for satellite investigations into global weather, upper atmospheric phenomena, and severe storms and local weather are summarized. Principle investigators and publications since June 1980 are listed.

LANDFILLS AS BIOREACTORS: RESEARH AT THE OUTER LOOP LANDFILL, LOUISVILLE, KENTUCKY; FIRST INTERIM REPORT

EPA Science Inventory

Interim report resulting from a cooperative research and development agreement (CRADA) between US EP A's Officeof Research and Development - National Risk Management Research Laboratory and a n ongoing field demonstration
of municipal waste landfills being operated as bioreact...

Ongoing data reduction, theoretical studies, and supporting research in magnetospheric physics

NASA Technical Reports Server (NTRS)

Scarf, F. L.; Greenstadt, E. W.

1982-01-01

The investigators published a very large number of space science research papers, and in almost all cases these papers involved correlative multi-spacecraft studies. A tabulation of these research papers is provided. Quarterly progress reports for the second contractual period are included.

Cognitive Profile: Increasing Student Performance.

ERIC Educational Resources Information Center

Letteri, Charles A.

Past and ongoing research on cognition indicates that its effects on academic achievement are more direct than those of environmental, affective, or behavioral factors. The research has analyzed cognitive factors, the remediation of cognitive differences, and the transferability of remediation practices. Other cognition researchers have focused on…

Symbiotic New Program Development through Marketing Research.

ERIC Educational Resources Information Center

Urban, David J.; And Others

1993-01-01

The applicability of marketing research to development of college programs in collaboration with other institutions or individuals is discussed. It is recommended that college administrators conduct ongoing environmental scanning to identify major opportunities for joint programs, forming research groups to screen basic ideas and explore program…

Ongoing Fixed Wing Research within the NASA Langley Aeroelasticity Branch

NASA Technical Reports Server (NTRS)

Bartels, Robert; Chwalowski, Pawel; Funk, Christie; Heeg, Jennifer; Hur, Jiyoung; Sanetrik, Mark; Scott, Robert; Silva, Walter; Stanford, Bret; Wiseman, Carol

2015-01-01

The NASA Langley Aeroelasticity Branch is involved in a number of research programs related to fixed wing aeroelasticity and aeroservoelasticity. These ongoing efforts are summarized here, and include aeroelastic tailoring of subsonic transport wing structures, experimental and numerical assessment of truss-braced wing flutter and limit cycle oscillations, and numerical modeling of high speed civil transport configurations. Efforts devoted to verification, validation, and uncertainty quantification of aeroelastic physics in a workshop setting are also discussed. The feasibility of certain future civil transport configurations will depend on the ability to understand and control complex aeroelastic phenomena, a goal that the Aeroelasticity Branch is well-positioned to contribute through these programs.

A randomized controlled trial of a smoking cessation self-help intervention for dual users of tobacco cigarettes and E-cigarettes: Intervention development and research design.

PubMed

Meltzer, Lauren R; Simmons, Vani N; Sutton, Steven K; Drobes, David J; Quinn, Gwendolyn P; Meade, Cathy D; Unrod, Marina; Brandon, Karen O; Harrell, Paul T; Eissenberg, Thomas; Bullen, Christopher R; Brandon, Thomas H

2017-09-01

Electronic Nicotine Delivery Systems, also called electronic cigarettes or e-cigarettes, have been available for over a decade and use has been increasing dramatically. The primary reported reasons for use are to aid smoking cessation or reduction, yet a significant proportion appear to be long-term users of both products ("dual users"). Dual users may be motivated to quit smoking and might benefit from a behavioral intervention for smoking cessation. This paper describes the intervention development, as well as the design, methods, and data analysis plans for an ongoing randomized controlled trial (RCT). Formative research and learner verification were conducted to create a usable, understandable, and acceptable self-help intervention targeting dual users. The efficacy is being tested in an RCT with current dual users (N=2900) recruited nationally and randomized to one of three conditions. The Assessment Only (ASSESS) group only completes assessments. The Generic Self-Help (GENERIC) group receives non-targeted smoking cessation booklets and supplemental materials sent monthly over 18months. The e-cigarette Targeted Self-Help (eTARGET) group receives the newly developed intervention (targeted booklets and supplemental materials) sent over the same period. All participants complete self-report surveys every 3months over 2years. The primary study outcome is self-reported 7-day point prevalence abstinence. Cost-effectiveness metrics for the GENERIC and eTARGET interventions will also be calculated. Copyright © 2017 Elsevier Inc. All rights reserved.

Developing Capacity for Research and Teaching in Higher Education: A Case of Makerere University

ERIC Educational Resources Information Center

Mugimu, Christopher B.; Nakabugo, Mary Goretti; Katunguka-Rwakishaya, Eli

2013-01-01

Research and teaching are key pillars in higher education. This article examines the factors associated with the current faculty research and teaching agenda at Makerere University (MU) and explores the realities of ongoing capacity building for faculty in research and teaching. This research was guided by the following questions: What motivates…

Learning from Older Citizens' Research Groups

ERIC Educational Resources Information Center

Munn-Giddings, Carol; McVicar, Andy; Boyce, Melanie; O'Brien, Niamh

2016-01-01

This article adds to an ongoing conversation in gerontology about the importance of training and involving older people in research. Currently, the literature rarely distinguishes between the one-off involvement of older citizens in research projects and the development of research groups led by older people that sustain over time as well as the…

The Need for Large-Scale, Longitudinal Empirical Studies in Middle Level Education Research

ERIC Educational Resources Information Center

Mertens, Steven B.; Caskey, Micki M.; Flowers, Nancy

2016-01-01

This essay describes and discusses the ongoing need for large-scale, longitudinal, empirical research studies focused on middle grades education. After a statement of the problem and concerns, the essay describes and critiques several prior middle grades efforts and research studies. Recommendations for future research efforts to inform policy…

Rocky Mountain Research Station invasive species visionary white paper

Treesearch

D. E. Pearson; M. Kim; J. Butler

2011-01-01

Invasive species represent one of the single greatest threats to natural ecosystems and the services they provide. Effectively addressing the invasive species problem requires management that is based on sound research. We provide an overview of recent and ongoing invasive species research conducted by Rocky Mountain Research Station scientists in the Intermountain...

A University-Community Partnership to Advance Research in Practice Settings: The HUB Research Model

ERIC Educational Resources Information Center

Dulmus, Catherine N.; Cristalli, Maria E.

2012-01-01

Human service organizations are uniquely positioned, given their scope of practice and access to consumers with the widest range of needs to significantly increase the national capacity for research if they were effectively equipped with the knowledge, skills, and funding to integrate research and development into their ongoing organizational…

A New Research Agenda for Educational Leadership and Policy

ERIC Educational Resources Information Center

Ball, Stephen J.

2011-01-01

This paper identifies some new research issues and sketches out some new research questions for education policy and leadership researchers as a response to ongoing changes in the landscape of English education policy. Three interrelated issues are considered: leadership, values and interests, and ownership. It argues for the need to ask new…

The Research and Evaluation of Serious Games: Toward a Comprehensive Methodology

ERIC Educational Resources Information Center

Mayer, Igor; Bekebrede, Geertje; Harteveld, Casper; Warmelink, Harald; Zhou, Qiqi; van Ruijven, Theo; Lo, Julia; Kortmann, Rens; Wenzler, Ivo

2014-01-01

The authors present the methodological background to and underlying research design of an ongoing research project on the scientific evaluation of serious games and/or computer-based simulation games (SGs) for advanced learning. The main research questions are: (1) what are the requirements and design principles for a comprehensive social…

A Combined Research/Educational Curriculum in Smart Sensors and Integrated Devices.

ERIC Educational Resources Information Center

Auner, G. W.; Siy, P.; Naik, R.; Wenger, L.; Liu, G-Y.; Schwiebert, L. J.

The researchers are developing a new curriculum which integrates ongoing research efforts in the Center for Smart Sensors and Integrated Devices into a cooperative educational and traineeship program. A forerunner to this program was initiated with funding by a National Science Foundation (NSF) Combined Research and Curriculum Development (CRCD)…

Using Pulsed Power for Hydrodynamic Code Validation

DTIC Science & Technology

2001-06-01

Air Force Research Laboratory ( AFRL ). A...bank at the Air Force Research Laboratory ( AFRL ). A cylindrical aluminum liner that is magnetically imploded onto a central target by self-induced...James Degnan, George Kiuttu Air Force Research Laboratory Albuquerque, NM 87117 Abstract As part of ongoing hydrodynamic code

Community-Based Research Assessments: Some Principles and Practices.

ERIC Educational Resources Information Center

Marullo, Sam; Cooke, Deanna; Willis, Jason; Rollins, Alexandra; Burke, Jacqueline; Bonilla, Paul; Waldref, Vanessa

2003-01-01

Examines benefits and challenges of undertaking assessments in community-based research (CBR). Such assessments are compared and contrasted to more traditional research processes. Further, the challenges of integrating CBR assessments into an ongoing social change initiative are analyzed. Five principles to guide CBR assessments are articulated. A…

Cost Sharing-Past, Present-and Future?

ERIC Educational Resources Information Center

Hardy, Robert B.

2000-01-01

Addresses ongoing issues in research cost sharing between government and universities in the context of the current Presidential Review Directive on the Government-University Research Partnership. Issues include the procurement vs. assistance conundrum, systemic shifting of costs of research from the government to universities, and the failure of…

Storying Literacies, Reimagining Classrooms: Teaching, Research, and Writing as Blurred Translating

ERIC Educational Resources Information Center

McManimon, Shannon K.

2014-01-01

I theorize teaching and researching as practices of "blurred translating" that center antioppressive education (Kumashiro, 2002) and storytelling (e.g., Frank, 2010; Zipes, 1995, 2004). Based in listening, research and teaching as blurred translating are relational, contextual, and ongoing processes oriented toward transformation and…

Interdisciplinary Research Training in Breast Cancer

DTIC Science & Technology

2006-07-01

McCorkle and Knobf, the study was published in Journal of Medical Internet Research . • Dr. LaCoursiere had begun an ongoing collaboration with Dr...patients’ self-reported attitudes about the Internet. Journal of Medical Internet Research , 7(3), e22. • LaCoursiere, S. P., & Sarkar, M. (2004

Shrinking streamflows in the Redwood Region

Treesearch

Randy. D. Klein; Tasha McKee; Katrina Nystrom

2017-01-01

The ongoing, severe drought in the redwood ecosystem has many ramifications, including loss of summer rearing habitat for juvenile salmonids. Many ‘perennial’ streams now cease to flow during parts of the summer and fall, either drying up completely or disconnecting pools as riffles go dry, subjecting fish to increased predation, high water temperatures, and...

Let No Child Be Left Inside - Propping Up Students Alertness to the World Around

ERIC Educational Resources Information Center

Abdul Gafoor, K.; Jouhar Munavvir, T.

2012-01-01

In a time of unprecedented, serious and ongoing threat of separation of education from nature, critical pedagogy is expected to play a constructive role in bringing education nearer to students' lives, environment and culture. This paper examines the extent to which students who have completed primary education by following the Kerala state school…

One Goal, Two Institutions: How a Community College and 4-Year University Partner to Bridge Student College Readiness Gaps

ERIC Educational Resources Information Center

Wilson, Dawna; Lowry, Kimberly M.

2017-01-01

Recent national attention on college completion poses unique challenges and opportunities for community colleges. Moving underprepared students through basic skills educational courses to degree attainment represents an ongoing challenge. With more than 60% of community college students enrolled in remedial education, 2-year institutions must…

The evolution of space mechanisms in the ESA R and D program

NASA Technical Reports Server (NTRS)

Wyn-Roberts, D.

1989-01-01

The status of recently completed and already ongoing technology developments, as well as some of the most important future developments of the European Space Agency are discussed. Among the subjects considered are Scientific Satellites, Columbus space station development, applications spacecraft for communications, Earth observation and meteorology, and the Ariane V and Hermes space transportation systems.

Task Interference in Time-Based, Event-Based, and Dual Intention Prospective Memory Conditions

ERIC Educational Resources Information Center

Hicks, Jason L.; Marsh, Richard L.; Cook, Gabriel I.

2005-01-01

Forming the intention to complete an activity later is the standard definition of a prospective memory task. Recently, a debate has arisen concerning the degree to which near-term intentions usurp resources away from other ongoing activities. In four experiments the authors tested how much interference was caused by holding a variety of different…

Proceedings - pinyon-juniper conference; 1986 January 13-16; Reno, NV

Treesearch

Richard L. Everett

1987-01-01

Includes more than 90 papers bringing together research accomplishments of the last 10 years including ongoing research on the ecology and management of pinyon-juniper ecosystems. Scientist and management points of view are presented.

Undergraduate Research and Economic Development: A Systems Approach in Wisconsin

ERIC Educational Resources Information Center

Van Galen, Dean; Schneider-Rebozo, Lissa; Havholm, Karen; Andrews, Kris

2015-01-01

This chapter presents the state of Wisconsin and the University of Wisconsin System as an ongoing case study for best practices in systematic, intentional, statewide programming and initiatives connecting undergraduate research and economic development.

Systematic reviews of therapeutic interventions frequently consider patient-important outcomes.

PubMed

Ameur, Hayet; Ravaud, Philippe; Fayard, Florence; Riveros, Carolina; Dechartres, Agnes

2017-04-01

To determine whether recently published and ongoing systematic reviews of therapeutic interventions assess patient-important outcomes. For this methodological review, we searched MEDLINE via PubMed for recently published systematic reviews and online registry of systematic reviews (PROSPERO) for ongoing systematic reviews. We selected systematic reviews with meta-analyses of randomized controlled trials. We extracted all outcomes defined in the methods section and categorized them. Mortality, other clinical events, pain, quality of life, function, and therapeutic decisions were considered patient-important outcomes. We included 420 systematic reviews: 90 Cochrane reviews, 200 other published reviews, and 130 registered ongoing reviews. Primary outcomes were defined in 85 Cochrane reviews (95%), 98 (49%) other published reviews and all ongoing reviews. At least one patient-important outcome was defined as a primary outcome in 81/85 Cochrane reviews (95%), 78/98 other published reviews (80%), and 117/130 ongoing reviews (90%). Considering all outcomes assessed, at least one patient-important outcome was evaluated in 90/90 Cochrane reviews (100%), 189/200 other published reviews (95%), and 121/130 ongoing reviews (93%). Most recent systematic reviews aim to assess patient-important outcomes, which contrasts with RCTs. These results suggest some important gaps between primary and secondary research. Copyright © 2017 Elsevier Inc. All rights reserved.

The Pretenure Years: A Longitudinal Perspective.

ERIC Educational Resources Information Center

Olsen, Deborah; Sorcinelli, Mary Deane

1992-01-01

A 5-year (still ongoing) study of new faculty (originally 54) has found such changes as declining amount of time spent on teaching preparation; teaching increasingly perceived as more satisfying and less stressful than research; increasing time spent on research; increased stress about research productivity; and increased perception of work…

Research Priorities in Childhood Disability: Conference Proceedings (London, Ontario, Canada, May 10-13, 1988).

ERIC Educational Resources Information Center

Easter Seal Research Inst., Don Mills (Ontario).

The conference reported in this document utilized a conceptual matrix to organize presentations on research priorities in prevention, definitive treatment, and ongoing management of impairment, disability, and handicap. Ten research strategy recommendations developed at the conference are offered for implementation by The Easter Seal Research…

Psychological Research in Educational Technology in China

ERIC Educational Resources Information Center

Ru-De, Liu

2010-01-01

Information and communication technology (ICT) has increasingly been bringing about significant changes in education in an ongoing process. The educational reform is not a mere technological issue but rather is based on an empirical grounding in a psychological research approach to learning and instruction. This paper introduces the research work…

76 FR 77545 - National Institute of Diabetes and Digestive and Kidney Diseases; Notice of Closed Meetings

Federal Register 2010, 2011, 2012, 2013, 2014

2011-12-13

... Diseases Special Emphasis Panel, Ancillary Studies to Major Ongoing Clinical Studies CKD. Date: January 9... Institute of Diabetes and Digestive and Kidney Diseases Special Emphasis Panel, Nutrition Obesity Research... and Metabolic Research; 93.848, Digestive Diseases and Nutrition Research; 93.849, Kidney Diseases...

Aerothermodynamics and Turbulence

DTIC Science & Technology

2013-03-08

Surface Heat Transfer and Detailed Flow Structure Fuel Injection in a Scramjet Combustor Reduced Uncertainty in Complex Flows Addressing... hypersonic flight data to capture shock interaction unsteadiness National Hypersonic Foundational Research Plan Joint Technology Office... Hypersonics Basic Science Roadmap Assessment of SOA and Future Research Directions Ongoing Basic Research for Understanding and Controlling Noise

NASA Wallops Flight Facility Air-Sea Interaction Research Facility

NASA Technical Reports Server (NTRS)

Long, Steven R.

1992-01-01

This publication serves as an introduction to the Air-Sea Interaction Research Facility at NASA/GSFC/Wallops Flight Facility. The purpose of this publication is to provide background information on the research facility itself, including capabilities, available instrumentation, the types of experiments already done, ongoing experiments, and future plans.

77 FR 69660 - Data Collection Available for Public Comments and Recommendations

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-20

... research firm to conduct quantitative data analysis of existing and available data to sketch the current... on a new information collection activity that is part of an ongoing research program. DATES: Submit... the collections to Emily Bruno, Director of Research and Policy, National Women's Business Council...

Engaging Students: An Authentic Undergraduate Research Experience

ERIC Educational Resources Information Center

Alderton, Elizabeth; Manzi, Michelina

2017-01-01

Engaging students in valuable undergraduate research can be an arduous task to craft outside of the regular schedule of both staff and students. This paper describes a successful research experience that was part of an ongoing methods class for undergraduate pre-service education students. Participants simultaneously engaged in community service…

Russian delegation visits NIH and NCI to discuss research collaboration

Cancer.gov

The NCI Center for Global Health hosted a delegation from the Russian Foundation for Basic Research to discuss ongoing and future collaborations in cancer research. The delegation was accompanied by representatives from the US Embassy in Moscow and the Embassy of the Russian Federation in Washington DC.

The Organizational Meaning of Research

ERIC Educational Resources Information Center

Adria, Marco; Boechler, Patricia

2004-01-01

Practitioners and theorists have given attention recently to the role and status of research activities in Canadian university continuing education units. For individuals in units that are increasing the proportion of their organizational activities devoted to research, there will be an ongoing process of cognitive change and development as a new…

On-going evaluation of traffic control devices.

DOT National Transportation Integrated Search

2010-09-01

This project was established to provide a means of conducting small-scale research activities on an as needed : basis so that the results could be available within months of starting the specific research. This report : summarizes the small-scale res...

Snow removal performance metrics : final report.

DOT National Transportation Integrated Search

2017-05-01

This document is the final report for the Clear Roads project entitled Snow Removal Performance Metrics. The project team was led by researchers at Washington State University on behalf of Clear Roads, an ongoing pooled fund research effort focused o...

Eighth workshop on seedling physiology and growth problems in oak plantings (abstracts). 2001 September 9-12; Hiwassee, GA.

Treesearch

S. Sung; P.P. Kormanik; W.J. Ostrosina; J.G. Isebrands

2002-01-01

Research results and ongoing research activities in field performance of planted trees, seedling propagation, physiology, genetics, acorn germination, and natural regeneration for oaks are described in 21 abstracts.

The Conservation Reserve Program: Planting for the future

USGS Publications Warehouse

Hyberg, Skip; Allen, Arthur

2006-01-01

Proceedings are now available from a scientific and technical forum held to review ongoing and planned research, identify lessons learned, and determine future research needs for the purpose of developing a rigorous scientific basis for future CRP policy discussions.

Sixth workshop on seedling physiology and growth problems in oak plantings (abstracts); 1995 September 18-20; Tomahawk, WI.

Treesearch

Ronald M. Teclaw

1996-01-01

Research results and ongoing research activities in field performance of planted trees, seedling propagation, physiology, genetics, acorn germination ,and natural regeneration for oaks are described in 29 abstracts.

Enabling Research Tools for Sustained Climate Assessment

NASA Technical Reports Server (NTRS)

Leidner, Allison K.; Bosilovich, Michael G.; Jasinski, Michael F.; Nemani, Ramakrishna R.; Waliser, Duane Edward; Lee, Tsengdar J.

2016-01-01

The U.S. Global Change Research Program Sustained Assessment process benefits from long-term investments in Earth science research that enable the scientific community to conduct assessment-relevant science. To this end, NASA initiated several research programs over the past five years to support the Earth observation community in developing indicators, datasets, research products, and tools to support ongoing and future National Climate Assessments. These activities complement NASA's ongoing Earth science research programs. One aspect of the assessment portfolio funds four "enabling tools" projects at NASA research centers. Each tool leverages existing capacity within the center, but has developed tailored applications and products for National Climate Assessments. The four projects build on the capabilities of a global atmospheric reanalysis (MERRA-2), a continental U.S. land surface reanalysis (NCA-LDAS), the NASA Earth Exchange (NEX), and a Regional Climate Model Evaluation System (RCMES). Here, we provide a brief overview of each enabling tool, highlighting the ways in which it has advanced assessment science to date. We also discuss how the assessment community can access and utilize these tools for National Climate Assessments and other sustained assessment activities.

LeaderBeing: Critical Reflections on Context, Character and Challenge in the Culture of Research and Its Administration

ERIC Educational Resources Information Center

Gabriele, Edward F.; Caines, Vaughan V.

2014-01-01

Servant leadership is a critical concept for understanding the ongoing importance of research administration as a central profession of service within the culture of research itself. The leadership of research administrators is both a unique gift and a challenge to the research culture. To ensure the continued productivity of the research…

Time to incorporate germline multigene panel testing into breast and ovarian cancer patient care.

PubMed

Graffeo, Rossella; Livraghi, Luca; Pagani, Olivia; Goldhirsch, Aron; Partridge, Ann H; Garber, Judy E

2016-12-01

Genetic evaluation is increasingly becoming an integral part of the management of women with newly diagnosed breast and ovarian cancer (OC), and of individuals at high risk for these diseases. Genetic counseling and testing have been incorporated into oncological care to help and complete management and treatment strategies. Risk assessment and early detection strategies in individuals with BRCA1/2 mutations and with Lynch syndrome have been quite extensively studied, whereas much less is known about the management of mutation carriers with less common high-penetrance cancer susceptibility genes (PTEN, TP53, STK11, CDH1), and particularly those who carry mutations in moderate-penetrance genes (e.g., PALB2, CHEK2, ATM, NF1, RAD51C, RAD51D, BRIP1). The latter patient groups represent important ongoing research opportunities to enable informed counseling about appropriate clinical management. We summarize the current guidelines for the management of high and moderate-penetrance mutations for breast and OC susceptibility. Continuous updating of guidelines for proper clinical management of these individuals is ongoing because of rapid advances in technology and knowledge in this field. Thus, we exhort the use of multigene panels for the assessment of cancer risk beyond the classic predisposition syndromes as a new standard of care in cancer genetics. We further support an increase of genetic counselors in Europe and use of their expertise to support genetic testing in specialist multidisciplinary teams.

Cohort profile: design and first results of the Dutch IBD Biobank: a prospective, nationwide biobank of patients with inflammatory bowel disease.

PubMed

Spekhorst, Lieke M; Imhann, Floris; Festen, Eleonora A M; van Bodegraven, Ad A; de Boer, Nanne K H; Bouma, Gerd; Fidder, Herma H; d'Haens, Geert; Hoentjen, Frank; Hommes, Daan W; de Jong, Dirk J; Löwenberg, Mark; Maljaars, P W Jeroen; van der Meulen-de Jong, Andrea E; Oldenburg, Bas; Pierik, Marieke J; Ponsioen, Cyriel Y; Stokkers, Pieter C; Verspaget, Hein W; Visschedijk, Marijn C; van der Woude, C Janneke; Dijkstra, Gerard; Weersma, Rinse K

2017-11-08

The Dutch IBD Biobank aims to facilitate the discovery of predictors for individual disease course and treatment response in patients with inflammatory bowel disease (IBD). In this paper, we aim to describe the establishment of the Dutch IBD Biobank, including the facilitators and barriers to establishment. Moreover, we aim to provide a complete overview of the content of the Dutch IBD Biobank. Since 2007, every patient with IBD treated in one of the eight Dutch university medical centres is asked to participate in the Dutch IBD Biobank in which 225 standardised IBD-related data items and biomaterials, such as serum, DNA, biopsies and a stool sample, are collected. As of June 2014, the Dutch IBD Biobank had enrolled 3388 patients with IBD: 2118 Crohn's disease (62.5%), 1190 ulcerative colitis (35.1%), 74 IBD-unclassified (2.2%) and 6 IBD-indeterminate (0.2%). The inclusion of patients with IBD is ongoing. The quality of the biomaterials is good and serum, DNA and biopsies have been used in newly published studies. The genotyping (750 000 genetic variants) of all participants of the Dutch IBD Biobank is currently ongoing, enabling more genetic research. In addition, all participants will start reporting disease activity and outcome measures using an online platform and mobile app . © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Pacific CRYSTAL Teacher Professional Development Models: Lessons Learned

NASA Astrophysics Data System (ADS)

van der Flier-Keller, E.; Yore, L.

2010-12-01

From 2005 to 2010 Pacific CRYSTAL (Centre for Research in Youth Science Teaching and Learning) has been engaged in community-based research fostering teacher leadership in innovative science education through a variety of approaches to teacher professional development. Pacific CRYSTAL is a University of Victoria based, NSERC funded project founded on a collaborative research model involving scentists, science educators and community members including schools, teachers, community groups and government. Pacific CRYSTAL professional development approaches embrace both in-service teachers and pre-service teachers, and include Lighthouse schools, workshops (ongoing as well as one-time), community-based partnerships in Pacific CRYSTAL research projects, teachers as researchers, and university science courses and workshops for pre-education and education students. A number of common themes, identified through these approaches, should be considered in the development and implementation of future science professional development initiatives. They include; teacher turnover, expanding and adding schools and participating teachers, teacher apprehension, building leadership capacity, further engagement of 'tourist' teachers, continuing professional support for teachers, as well as on-going mentoring.

Federal Geothermal Research Program Update, FY 2000

DOE Office of Scientific and Technical Information (OSTI.GOV)

Renner, Joel Lawrence

2001-08-01

The Department of Energy's Geothermal Program serves two broad purposes: 1) to assist industry in overcoming near-term barriers by conducting cost-shared research and field verification that allows geothermal energy to compete in today's aggressive energy markets; and 2) to undertake fundamental research with potentially large economic payoffs. The four categories of work used to distinguish the research activities of the Geothermal Program during FY 2000 reflect the main components of real-world geothermal projects. These categories form the main sections of the project descriptions in this Research Update. Exploration Technology research focuses on developing instruments and techniques to discover hidden hydrothermalmore » systems and to explore the deep portions of known systems. Research in geophysical and geochemical methods is expected to yield increased knowledge of hidden geothermal systems. Reservoir Technology research combines laboratory and analytical investigations with equipment development and field testing to establish practical tools for resource development and management for both hydrothermal reservoirs and enhanced geothermal systems. Research in various reservoir analysis techniques is generating a wide range of information that facilitates development of improved reservoir management tools. Drilling Technology focuses on developing improved, economic drilling and completion technology for geothermal wells. Ongoing research to avert lost circulation episodes in geothermal drilling is yielding positive results. Conversion Technology research focuses on reducing costs and improving binary conversion cycle efficiency, to permit greater use of the more abundant moderate-temperature geothermal resource, and on the development of materials that will improve the operating characteristics of many types of geothermal energy equipment. Increased output and improved performance of binary cycles will result from investigations in heat cycle research.« less

Federal Geothermal Research Program Update Fiscal Year 2000

DOE Office of Scientific and Technical Information (OSTI.GOV)

Renner, J.L.

2001-08-15

The Department of Energy's Geothermal Program serves two broad purposes: (1) to assist industry in overcoming near-term barriers by conducting cost-shared research and field verification that allows geothermal energy to compete in today's aggressive energy markets; and (2) to undertake fundamental research with potentially large economic payoffs. The four categories of work used to distinguish the research activities of the Geothermal Program during FY 2000 reflect the main components of real-world geothermal projects. These categories form the main sections of the project descriptions in this Research Update. Exploration Technology research focuses on developing instruments and techniques to discover hidden hydrothermalmore » systems and to explore the deep portions of known systems. Research in geophysical and geochemical methods is expected to yield increased knowledge of hidden geothermal systems. Reservoir Technology research combines laboratory and analytical investigations with equipment development and field testing to establish practical tools for resource development and management for both hydrothermal reservoirs and enhanced geothermal systems. Research in various reservoir analysis techniques is generating a wide range of information that facilitates development of improved reservoir management tools. Drilling Technology focuses on developing improved, economic drilling and completion technology for geothermal wells. Ongoing research to avert lost circulation episodes in geothermal drilling is yielding positive results. Conversion Technology research focuses on reducing costs and improving binary conversion cycle efficiency, to permit greater use of the more abundant moderate-temperature geothermal resource, and on the development of materials that will improve the operating characteristics of many types of geothermal energy equipment. Increased output and improved performance of binary cycles will result from investigations in heat cycle research.« less

Snapshots of Authentic Scientific Inquiry and Teacher Preparation: Undergraduate STEM Courses, Preservice and Inservice Teachers' Experiences

NASA Astrophysics Data System (ADS)

French, Debbie Ann

In this dissertation, the researcher describes authentic scientific inquiry (ASI) within three stages of teacher preparation and development: a1) undergraduate STEM courses, b2) preservice secondary science education methods courses, and c3) inservice teacher professional development (PD). Incorporating (ASI)-- pedagogy closely modeling the research practices of scientists--is at the forefront of national science, technology, engineering, and mathematics (STEM) initiatives and the Next Generation Science Standards (NGSS). In the first of three research articles, 42 students participated in an introductory astronomy course which employed inquiry-based pedagogy. The researcher administered the Test Of Astronomy STandards (TOAST) pre/post instruction. In the second article, 56 preservice secondary science teachers completed ideal lesson plan scenarios before and after 80 hours of methods instruction. The researcher scored the scenarios using a rubrirubric developedc according to the NGSS Science and Engineering Practices, and analyzed the components from the scenarios. The third article surveyed 63 inservice STEM teachers with prior research and industry experience. The researcher highlights teacher ASI perspectives. Overall, teachers incorporated opportunities for K-20 students to use scientific instrumentation and technology to collect and analyze data, work collaboratively, and develop evidence-based conclusions. Few teachers provided opportunities for students to ask scientific questions or disseminate results, suggesting the need that teachers (at all levels) need scaffolded instruction in these areas. The researcher argues that while ASI and STEM PDs are effective for teachers, developing similar interest, on-going communities of practice may provide support for teacher to implement the ASI practices in their classrooms.

Proprioception in Dance: A Comparative Review of Understandings and Approaches to Research

ERIC Educational Resources Information Center

Barlow, Rachel

2018-01-01

Proprioception is an ongoing topic of interest in dance research. Yet 'proprioception' can have a wide range of meanings, and therefore is studied in many different ways. This research presents a review of existing studies of proprioception in dance. The review comprised 4 main stages: stage (1) background research; stage (2) proposing a working…

26th USDA interagency research forum on invasive species

Treesearch

Katherine A. McManus; Kurt W. Gottschalk

2015-01-01

This meeting was the 26th in a series of annual USDA Interagency Research Forums that are sponsored by the Forest Service, Animal and Plant Health Inspection Service, National Institute of Food and Agriculture, and Agriculture Research Service. The Group's original goal of fostering communication and providing a forum for the overview of ongoing research among the...

XXVII (28th) USDA interagency research forum on invasive species

Treesearch

Katherine A. McManus; Therese M. Poland

2017-01-01

This meeting was the 28th in a series of annual USDA Interagency Research Forums that are sponsored by the Forest Service, Animal and Plant Health Inspection Service, National Institute of Food and Agriculture, and Agriculture Research Service. The Group's original goal of fostering communication and providing a forum for the overview of ongoing research among the...

Using Electronic Communication to Bridge the Research to Practice Gap among Mentoring Professionals

ERIC Educational Resources Information Center

Smith, Cindy Ann; Willox, Lara; Olds, Courtney

2017-01-01

The field of mentoring includes a broad base of stakeholders, such as researchers and practitioners who implement mentoring programs. The research-to-practice gap is an ongoing area of concern in many fields of social science including mentoring. One reason for this is that researchers and practitioners often operate in isolation. Technology is…

Learning from Mistakes and Moving Forward in Intercultural Research with Aboriginal and Torres Strait Islander Peoples

ERIC Educational Resources Information Center

McLennan, Vanette; Woods, Glenn

2018-01-01

The ongoing challenges in equitable research involving Indigenous peoples and their communities and ways to overcome these are discussed in this article. Central to this article is the narrative reflection of a non-Indigenous researcher following research on Indigenous spirituality, well-being and resilience in the Yaegl community of northern New…

Research Literacy: Contextual Affordances and the Ongoing Quest for Sustainability and Research Quality

ERIC Educational Resources Information Center

Waring, Michael

2017-01-01

This article provides a brief review of three papers. It is specifically focused on Early Career Teachers (ECTs) ownership and integration of the "research process" as part of a legitimate and sustainable process of integrating research into professional practice. All of the ECTs followed a similar structure for the presentation of their…

EXPLORING PATERNAL MATURITY IN THE RELATIONSHIPS BETWEEN OLDER FATHERS AND ADULT CHILDREN

PubMed Central

STELLE, CHARLIE D.; SHEEHAN, NANCY W.

2013-01-01

While research on parent-adult child relationships has expanded over the last two decades, most research has ignored the experiences of older fathers and their relationships with adult children. The present study sought to explore how midlife and older men assess the costs and rewards associated with their fatherhood experiences and how fathers’ level of paternal maturity influences their perceptions of fatherhood. More specifically, the purpose of the present study was two-fold: to explore the costs and rewards of fatherhood and whether paternal maturity serves as a moderator of older men’s fatherhood experiences. A purposive sample of 96 fathers (age 50–80) completed measures assessing ego development, generativity, and costs and rewards of fatherhood. The construct of paternal maturity, hypothesized to influence assessment of fatherhood experiences, was operationally defined as combining both affective (generativity) and cognitive (ego development) levels of psychological maturity. Results indicate mixed support for the influence of paternal maturity on fathers’ perceptions of costs and rewards. Overall, findings note that the affective side of maturity (generativity) is more strongly associated with fathers’ accounts of the costs and rewards than the cognitive side of maturity (ego development). Discussion centers on the utility of these concepts and the implications for continued research into the ongoing relationships between fathers and adult children. PMID:21391406

Space Engineering Projects in Design Methodology

NASA Technical Reports Server (NTRS)

Crawford, R.; Wood, K.; Nichols, S.; Hearn, C.; Corrier, S.; DeKunder, G.; George, S.; Hysinger, C.; Johnson, C.; Kubasta, K.

1993-01-01

NASA/USRA is an ongoing sponsor of space design projects in the senior design courses of the Mechanical Engineering Department at The University of Texas at Austin. This paper describes the UT senior design sequence, focusing on the first-semester design methodology course. The philosophical basis and pedagogical structure of this course is summarized. A history of the Department's activities in the Advanced Design Program is then presented. The paper includes a summary of the projects completed during the 1992-93 Academic Year in the methodology course, and concludes with an example of two projects completed by student design teams.

Book review: Oklahoma Breeding Bird Atlas

USGS Publications Warehouse

Peterjohn, Bruce G.

2004-01-01

The first North American breeding bird atlases were initiated during the 1970s. With atlases completed or ongoing in more than 40 U.S. states and most Canadian provinces, these projects are now familiar to professional ornithologists and amateur birders. This book provides the results of the Oklahoma Breeding Bird Atlas, the data for which were collected during 1997–2001. Its appearance less than 3 years after completing fieldwork is remarkable and everyone associated with its timely publication should be congratulated for their efforts.Review info: Oklahoma Breeding Bird Atlas. By Dan L. Reinking, 2004. ISBN: 0806136146, 528 pp.

The Genomes On Line Database (GOLD) v.2: a monitor of genome projects worldwide

PubMed Central

Liolios, Konstantinos; Tavernarakis, Nektarios; Hugenholtz, Philip; Kyrpides, Nikos C.

2006-01-01

The Genomes On Line Database (GOLD) is a web resource for comprehensive access to information regarding complete and ongoing genome sequencing projects worldwide. The database currently incorporates information on over 1500 sequencing projects, of which 294 have been completed and the data deposited in the public databases. GOLD v.2 has been expanded to provide information related to organism properties such as phenotype, ecotype and disease. Furthermore, project relevance and availability information is now included. GOLD is available at . It is also mirrored at the Institute of Molecular Biology and Biotechnology, Crete, Greece at PMID:16381880

Dealing with prospective memory demands while performing an ongoing task: Shared processing, increased on-task focus, or both?

PubMed

Rummel, Jan; Smeekens, Bridget A; Kane, Michael J

2017-07-01

Prospective memory (PM) is the cognitive ability to remember to fulfill intended action plans at the appropriate future moment. Current theories assume that PM fulfillment draws on attentional processes. Accordingly, pending PM intentions interfere with other ongoing tasks to the extent to which both tasks rely on the same processes. How do people manage the competition between PM and ongoing-task demands? Based on research relating mind wandering and attentional control (Kane & McVay, 2012), we argue that people may not only change the way they process ongoing-task stimuli when given a PM intention, but they may also engage in less off-task thinking than they otherwise would. That is, people focus more strongly on the tasks at hand and dedicate considerable conscious thought to the PM goal. We tested this hypothesis by asking subjects to periodically report on their thoughts during prototypical PM (and control) tasks. Task-unrelated thought rates dropped when participants performed an ongoing task while holding a PM intention versus performing the ongoing task alone (Experiment 1), even when PM demands were minimized (Experiment 2) and more so when PM execution was especially rewarded (Experiment 3). Our findings suggest that PM demands not only elicit a cost to ongoing-task processing, but they also induce a stronger on-task focus and promote conscious thoughts about the PM intention. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Growing older with post-traumatic stress disorder.

PubMed

Curran, B; Collier, E

2016-04-01

WHAT IS KNOWN ON THE SUBJECT?: The needs of older people with long-term mental illness are not very well addressed in policy and research. Older people are not a homogenous group and people ageing with long-term mental illness have potentially unique or specific needs. WHAT THIS PAPER ADDS TO EXISTING KNOWLEDGE?: A unique example of the idiosyncratic and contextual nature of individual strengths and the abilities in managing personal recovery when experiencing long-term mental illness. Emotional exhaustion experienced after long-term mental health compromises the ability to manage feelings, potentially a special feature of life time mental ill health. WHAT ARE THE IMPLICATIONS FOR PRACTICE?: Recognition that the hard work involved in successfully managing long-term personal recovery may be important in preventing suicide in later life. The need to understand a person's life story to make sense of their experience of mental illness and to recognize long-term mental illness to later life as part of a persons' established identity. The importance of appreciating the place of early memories for understanding older person's mental health in their present. Introduction Ageing with mental illness is a neglected area of research and policy. People who grow older to later life with ongoing mental health problems may not have their needs well understood. This understanding is important if mental health services are to ensure direct or indirect age discrimination is avoided. Aim This paper aims to explore issues relating to later life and ageing with mental illness focused on the story of Bernard (who was 84 years of age at the time of writing) who lived with a diagnosis of post-traumatic stress disorder (PTSD). Method The paper is co-authored by Bernard and the researcher he originally told his story to as a participant in a biographical research study exploring mental ill health through the life course. In the original research study, Bernard completed a curriculum vitae (CV) of his life which informed two personalised interviews. An edited version of this is presented in this paper. Implications for practice are discussed in the context of life course, recovery, self-help and preventing suicide. The narrative illustrates how time, memory and meaning interweave and how ageing with mental illness become part of a person's ongoing identity. © 2016 John Wiley & Sons Ltd.

Time to finger point or fix? An invitation to join ongoing efforts to promote ethical authorship and other good publication practices.

PubMed

Woolley, Karen L; Gertel, Art; Hamilton, Cindy W; Jacobs, Adam; Snyder, Gene P

2013-01-01

In this commentary, we present evidence that unethical authorship (eg, guest and ghost authoring) and other publication practices are not restricted to the pharmaceutical industry; they also occur in academia. Such practices are not an industry problem--they are a research problem. To enhance trust in industry-sponsored research, companies have made rapid and far-reaching changes to their publication guidelines, policies, and procedures. Professional medical writers have adopted, and continue to implement, these changes. Although evidence indicates that industry practices are improving, there is certainly more to do, both in industry and academia. We invite readers to join ongoing efforts to promote ethical publication practices.

Learning How Scientists Work: Experiential Research Projects to Promote Cell Biology Learning and Scientific Process Skills

PubMed Central

2002-01-01

Facilitating not only the mastery of sophisticated subject matter, but also the development of process skills is an ongoing challenge in teaching any introductory undergraduate course. To accomplish this goal in a sophomore-level introductory cell biology course, I require students to work in groups and complete several mock experiential research projects that imitate the professional activities of the scientific community. I designed these projects as a way to promote process skill development within content-rich pedagogy and to connect text-based and laboratory-based learning with the world of contemporary research. First, students become familiar with one primary article from a leading peer-reviewed journal, which they discuss by means of PowerPoint-based journal clubs and journalism reports highlighting public relevance. Second, relying mostly on primary articles, they investigate the molecular basis of a disease, compose reviews for an in-house journal, and present seminars in a public symposium. Last, students author primary articles detailing investigative experiments conducted in the lab. This curriculum has been successful in both quarter-based and semester-based institutions. Student attitudes toward their learning were assessed quantitatively with course surveys. Students consistently reported that these projects significantly lowered barriers to primary literature, improved research-associated skills, strengthened traditional pedagogy, and helped accomplish course objectives. Such approaches are widely suited for instructors seeking to integrate process with content in their courses. PMID:12669101

Mental health issues from rising sea level in a remote coastal region of the Solomon Islands: current and future.

PubMed

Asugeni, James; MacLaren, David; Massey, Peter D; Speare, Rick

2015-12-01

There is little published research about mental health and climate change in the Pacific, including Solomon Islands. Solomon Islands has one of the highest rates of sea-level rise globally. The aim of this research was to document mental health issues related to sea-level rise for people in East Malaita, Solomon Islands. A cross-sectional study was carried out in six low-lying villages in East Malaita, Solomon Islands. The researcher travelled to villages by dugout canoe. In addition to quantitative, closed-ended questions, open-ended questions with villagers explored individual and community responses to rising sea level. Of 60 people asked, 57 completed the questionnaire. Of these, 90% reported having seen a change in the weather patterns. Nearly all participants reported that sea-level rise is affecting them and their family and is causing fear and worry on a personal and community level. Four themes emerged from the qualitative analysis: experience of physical impacts of climate change; worry about the future; adaptation to climate change; government response needed. Given predictions of ongoing sea-level rise in the Pacific it is essential that more research is conducted to further understand the human impact of climate change for small island states which will inform local, provincial and national-level mental health responses. © The Royal Australian and New Zealand College of Psychiatrists 2015.

Learning how scientists work: experiential research projects to promote cell biology learning and scientific process skills.

PubMed

DebBurman, Shubhik K

2002-01-01

Facilitating not only the mastery of sophisticated subject matter, but also the development of process skills is an ongoing challenge in teaching any introductory undergraduate course. To accomplish this goal in a sophomore-level introductory cell biology course, I require students to work in groups and complete several mock experiential research projects that imitate the professional activities of the scientific community. I designed these projects as a way to promote process skill development within content-rich pedagogy and to connect text-based and laboratory-based learning with the world of contemporary research. First, students become familiar with one primary article from a leading peer-reviewed journal, which they discuss by means of PowerPoint-based journal clubs and journalism reports highlighting public relevance. Second, relying mostly on primary articles, they investigate the molecular basis of a disease, compose reviews for an in-house journal, and present seminars in a public symposium. Last, students author primary articles detailing investigative experiments conducted in the lab. This curriculum has been successful in both quarter-based and semester-based institutions. Student attitudes toward their learning were assessed quantitatively with course surveys. Students consistently reported that these projects significantly lowered barriers to primary literature, improved research-associated skills, strengthened traditional pedagogy, and helped accomplish course objectives. Such approaches are widely suited for instructors seeking to integrate process with content in their courses.

MiYoga: a randomised controlled trial of a mindfulness movement programme based on hatha yoga principles for children with cerebral palsy: a study protocol

PubMed Central

Whittingham, Koa; Cunnington, Ross; Boyd, Roslyn N

2017-01-01

Introduction Cerebral palsy (CP) is the most common childhood physical disability, with life-long impacts for 1.77 in 1000 children. Although CP is primarily a physical disability, children with CP have an increased risk of experiencing cognitive difficulties, particularly attention and executive function deficits. Impairment in cognitive abilities can lead to subsequent impairment in independent functioning, education, employment and interpersonal relationships. This paper reports the protocol of a randomised controlled trial of a novel family-centred lifestyle intervention based on mindfulness and hatha yoga principles (MiYoga). MiYoga aims to enhance child and parent outcomes for children with CP. Methods and analysis The aim is to recruit 36 child-parent dyads (children aged 6–16 years; bilateral or unilateral CP; Gross Motor Function Classification System I–III), who will be randomly assigned to two groups: MiYoga andwaitlistt control. The MiYoga programme will be facilitated in a group format for 8 weeks. Assessments will be administered at baseline, prior to MiYoga, following completion of MiYoga, and at 6-month follow-up (retention). The primary outcome will be the child’s sustained attentional ability as measured by the Conner’s Continuous Performance Test II. Other outcomes of interest for children with CP consists of attentional control, physical functioning, behavioural and well-being. For parents, the outcomes of interest are mindfulness, psychological flexibility and well-being. Data will be analysed using general linear models, specifically analysis of covariance and analysis of variance. Ethics and dissemination Full ethical approval for this study has been obtained by the Children’s Health Queensland Hospital and Health Service Research Ethics Committee (HREC/12/QRCH/120) and The University of Queensland (2012000993). If MiYoga is proven effective, its dissemination would assist children with CP and complement their ongoing therapy by improving the ability of the child to pay attention at school and in therapy, and alleviating environmentalstressorss for both the child and his/her parents. Trial registration number ACTRN12613000729729; Pre-results.http://www.ANZCTR.org.au/ACTRN12613000729729.aspx Date of trial registration Prospectively registered on 2 July 2013–present (ongoing). Findings to date Recruitment is complete. Data are still being collected at present. We aim to complete data collection by February 2017. PMID:28698326

Nutritional supplements for patients being treated for active visceral leishmaniasis.

PubMed

Custodio, Estefanía; López-Alcalde, Jesús; Herrero, Mercè; Bouza, Carmen; Jimenez, Carolina; Storcksdieck Genannt Bonsmann, Stefan; Mouratidou, Theodora; López-Cuadrado, Teresa; Benito, Agustin; Alvar, Jorge

2018-03-26

Visceral leishmaniasis (VL) is a disease caused by a parasite, which can lead to death if untreated. Poor nutritional status hastens the progression of VL infection, and VL worsens malnutrition status. Malnutrition is one of the poor prognostic factors identified for leishmaniasis. However, the effects of nutritional supplementation in people treated for VL are not known. To assess the effects of oral nutritional supplements in people being treated with anti-leishmanial drug therapy for VL. We searched the Cochrane Infectious Diseases Group (CIDG) Specialized Register, CENTRAL, MEDLINE, Embase, LILACS, and two trial registers up to 12 September 2017. We checked conference proceedings and WHO consultative meeting reports, the reference lists of key documents and existing reviews, and contacted experts and nutritional supplement companies. Randomized controlled trials (RCTs), quasi-randomized controlled trials (quasi-RCTs), and non-randomized controlled trials (NRCTs) of any oral nutritional supplement, compared to no nutritional intervention, placebo, or dietary advice alone, in people being treated for VL. Two review authors independently screened the literature search results for studies that met the inclusion criteria. We had planned for two review authors to independently extract data and assess the risk of bias of the included studies. We planned to follow the Cochrane standard methodological procedures for assessing risk of bias and analysing the data. We identified no eligible studies for this review, either completed or ongoing. We found no studies, either completed or ongoing, that assessed the effects of oral nutritional supplements in people with VL who were being treated with anti-leishmanial drug therapy. Thus, we could not draw any conclusions on the impact of these interventions on primary cure of VL, definitive cure of VL, treatment completion, self-reported recovery from illness or resolution of symptoms, weight gain, increased skinfold thickness, other measures of lean or total mass, or growth in children.This absence of evidence should not be interpreted as evidence of no effect for nutritional supplements in people under VL treatment. It means that we did not identify research that fulfilled our review inclusion criteria.The effects of oral nutritional supplements in people with VL who are being treated with anti-leishmanial drug therapy have yet to be determined by rigorous experimental studies, such as cluster-randomized trials, that focus on outcomes relevant for patients.

Seventh workshop on seedling physiology and growth problems in oak plantings (abstracts); 1998 September 27-29; South Lake Tahoe, CA.

Treesearch

D.D. McCreary; J.G. Isebrands

1999-01-01

Research results and ongoing research activities in field performance of planted trees, seedling propagation, physiology, genetics, acorn germination, and natural regeneration for oaks are described in 17 abstracts.

POLLUTION PREVENTION RESEARCH WITHIN THE FEDERAL COMMUNITY

EPA Science Inventory

One of the primary ongoing programs for promotion and encouragement of pollution prevention research is a cooperative program between the U.S. Environmental Protection Agency (EPA) and the Federal community at large. EPA’s Waste Reduction Evaluations At Federal Sites (WREAFS) Pro...

76 FR 1138 - Enhanced Assessment Instruments

Federal Register 2010, 2011, 2012, 2013, 2014

2011-01-07

... priorities: (a) Collaborating with institutions of higher education, other research institutions, or other... a member State may hold); (2) The consortium's method and process (e.g., consensus, majority) for... available on an ongoing basis for research, including for prospective linking, validity, and program...

Rehabilitation Technologies for Water Mains

EPA Science Inventory

This paper presents on-going research work for the USEPA Research Project on “Rehabilitation of Water and Wastewater Systems.” It will compare various renewal methods (i.e. replacement, rehabilitation and repair technologies that are available in the market). The paper discusse...

78 FR 78373 - National Institute of Diabetes and Digestive and Kidney Diseases Notice of Closed Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2013-12-26

... Ongoing Clinical Studies in NIDDK (RO1): CKD and Diabetic Nephropathy. Date: February 20, 2014. Time: 4:00... and Metabolic Research; 93.848, Digestive Diseases and Nutrition Research; 93.849, Kidney Diseases...

STORMWATER BEST MANAGEMENT PRACTICES TEST FACILITY - SWALES

EPA Science Inventory

The NRMRL swale evaluation is part of a larger collection of long-term research projects that evaluates many Best Management Practices. EPA has ongoing research examining the performance of constructed wet lands, and detention and retention ponds. Other projects will evaluate ra...

VENTILATION RESEARCH: A REVIEW OF RECENT INDOOR AIR QUALITY LITERATURE

EPA Science Inventory

The report gives results of a literature review, conducted to survey and summarize recent and ongoing engineering research into building ventilation, air exchange rate, pollutant distribution and dispersion, and other effects of heating, ventilation, and air-conditioning (HVAC) s...

PCC Airfield Pavement Response During Thaw-Weakening Periods: A Field Study

DOT National Transportation Integrated Search

1996-05-01

This investigation is part of the Cold Regions Research and Engineering Laboratory's (CRREL) on-going characterization of pavement performance in seasonal frost areas. As part of the research, CRREL conducted several field studies for the Federal Avi...

What is Research Anyway?

ERIC Educational Resources Information Center

Loeffler, Margaret

1998-01-01

Maintains that Montessori educators should become "scientific pedagogues" who look upon their classrooms as ongoing educational experiments, and that their task is to match strategies, content, and emotional understanding to the children's developmental needs, interests, and culture. Describes components of successful research within the…

Present and future of astronomy in Thailand

NASA Astrophysics Data System (ADS)

Soonthornthum, Boonrucksar

2018-05-01

Investments in national astronomical facilities and human resources through the National Astronomical Research Institute of Thailand have led to the rapid growth of astronomy in Thailand. Ongoing activities in key research areas, education and outreach will lead to further sustainable development.

Translating Alcohol Research

PubMed Central

Batman, Angela M.; Miles, Michael F.

2015-01-01

Alcohol use disorder (AUD) and its sequelae impose a major burden on the public health of the United States, and adequate long-term control of this disorder has not been achieved. Molecular and behavioral basic science research findings are providing the groundwork for understanding the mechanisms underlying AUD and have identified multiple candidate targets for ongoing clinical trials. However, the translation of basic research or clinical findings into improved therapeutic approaches for AUD must become more efficient. Translational research is a multistage process of streamlining the movement of basic biomedical research findings into clinical research and then to the clinical target populations. This process demands efficient bidirectional communication across basic, applied, and clinical science as well as with clinical practitioners. Ongoing work suggests rapid progress is being made with an evolving translational framework within the alcohol research field. This is helped by multiple interdisciplinary collaborative research structures that have been developed to advance translational work on AUD. Moreover, the integration of systems biology approaches with collaborative clinical studies may yield novel insights for future translational success. Finally, appreciation of genetic variation in pharmacological or behavioral treatment responses and optimal communication from bench to bedside and back may strengthen the success of translational research applications to AUD. PMID:26259085

Translating Alcohol Research: Opportunities and Challenges.

PubMed

Batman, Angela M; Miles, Michael F

2015-01-01

Alcohol use disorder (AUD) and its sequelae impose a major burden on the public health of the United States, and adequate long-term control of this disorder has not been achieved. Molecular and behavioral basic science research findings are providing the groundwork for understanding the mechanisms underlying AUD and have identified multiple candidate targets for ongoing clinical trials. However, the translation of basic research or clinical findings into improved therapeutic approaches for AUD must become more efficient. Translational research is a multistage process of stream-lining the movement of basic biomedical research findings into clinical research and then to the clinical target populations. This process demands efficient bidirectional communication across basic, applied, and clinical science as well as with clinical practitioners. Ongoing work suggests rapid progress is being made with an evolving translational framework within the alcohol research field. This is helped by multiple interdisciplinary collaborative research structures that have been developed to advance translational work on AUD. Moreover, the integration of systems biology approaches with collaborative clinical studies may yield novel insights for future translational success. Finally, appreciation of genetic variation in pharmacological or behavioral treatment responses and optimal communication from bench to bedside and back may strengthen the success of translational research applications to AUD.

Investing in African research training institutions creates sustainable capacity for Africa: the case of the University of the Witwatersrand School of Public Health masters programme in epidemiology and biostatistics

PubMed Central

2012-01-01

Background Improving health in Africa is a high priority internationally. Inadequate research capacity to produce local, relevant research has been identified as a limitation to improved population health. Increasing attention is being paid to the higher education sector in Africa as a method of addressing this; evidence that such investment is having the desired impact is required. A 1998 3-year investment by the Special Programme for Research and Training in Tropical Diseases (TDR) in research training at the School of Public Health, University of the Witwatersrand, South Africa was reviewed to assess its' impact. Methods A descriptive cross-sectional survey of the 70 students registered for the masters programme in epidemiology & biostatistics from 2000-2005 was conducted. Data were collected from self-administered questionnaires. Results Sixty percent (42/70) of students responded. At the time of the survey 19% of respondents changed their country of residence after completion of the masters course, 14% migrated within Africa and 5% migrated out of Africa. Approximately half (47%) were employed as researchers and 38% worked in research institutions. Sixty percent reported research output, and four graduates were pursuing PhD studies. Government subsidy to higher education institutions, investments of the University of the Witwatersrand in successful programmes and ongoing bursaries for students to cover tuition fees were important for sustainability. Conclusions Investing in African institutions to improve research training capacity resulted in the retention of graduates in Africa in research positions and produced research output. Training programmes can be sustained when national governments invest in higher education and where that funding is judiciously applied. Challenges remain if funding for students bursaries is not available. PMID:22475629

Research Progress and Accomplishments on ISS

NASA Technical Reports Server (NTRS)

Roe, Lesa B.; Uri, John J.

2002-01-01

The first research payloads reached the International Space Station (ISS) more than two years ago, with research operating continuously since March 2001. Seven research racks are currently on-orbit, with three more arriving soon to expand science capabilities. Through the first five expeditions, 60 unique NASA-managed investigations from 11 nations have been supported, many continuing into later missions. More than 90,000 experiment hours have been completed, and more than 1,000 hours of crew time have been dedicated to research, numbers that grow daily. The multidisciplinary program includes research in life sciences, physical sciences, biotechnology, Earth sciences, technology demonstrations as well as commercial endeavors and educational activities. The Payload Operations and Integration Center monitors the onboard activities around the clock, working with numerous Principal Investigators and Payload Developers at their remote sites. Future years will see expansion of the station with research modules provided by the European Space Agency and Japan, which will be outfitted with additional research racks. The first research payloads arrived at ISS more than two years ago, and continuous science has been ongoing for more than one and a half years. During this time, the research capabilities have been tremendously increased, even as assembly of the overall platform continues. Despite significant challenges along the way, ISS continues to successfully support a large number of investigations in a variety of research disciplines. The results of some of the early investigations are reaching the publication stage. The near future looms with new challenges, but experience to date and dedicated efforts give reason to be optimistic that the challenges will be overcome and that new and greater successes will be added to past ones.

Developing a Rural and Regional Science Challenge to Utilise Community and Industry-Based Partnerships

ERIC Educational Resources Information Center

Blake, Damian; Campbell, Coral

2009-01-01

Interest and participation in science in schools has been declining for many years and there is a genuine need to rejuvenate interest in science at the high school level. One possible solution is the completion of challenging science projects which fulfill an authentic purpose in the community. This paper discusses the results of ongoing research…

Growth and Predictors of Parental Knowledge of Youth Behavior during Early Adolescence

ERIC Educational Resources Information Center

Moilanen, Kristin L.; Shaw, Daniel S.; Criss, Michael M.; Dishion, Thomas J.

2009-01-01

The current study examines latent growth models of parental knowledge of boys' behavior from ages 10 to 15, and whether earlier child or family characteristics are related to intercept and growth in parental knowledge. As part of an ongoing longitudinal study on the precursors of antisocial behavior, 288 boys completed interviews at ages 10, 11,…

Influence of Computer-Aided Assessment on Ways of Working with Mathematics

ERIC Educational Resources Information Center

Rønning, Frode

2017-01-01

This paper is based on an on-going project for modernizing the basic education in mathematics for engineers at the Norwegian University of Science and Technology. One of the components in the project is using a computer-aided assessment system (Maple T.A.) for handling students' weekly hand-ins. Successful completion of a certain number of problem…

Lifelong Learning: The Value of an Industrial Internship for a Graduate Student Education

ERIC Educational Resources Information Center

Honda, Gregory S.; Pazmino, Jorge H.; Hickman, Daniel A.; Varma, Arvind

2015-01-01

A chemical engineering PhD student from Purdue University completed an internship at The Dow Chemical Company, evaluating the effect of scale on the hydrodynamics of a trickle bed reactor. A unique aspect of this work was that it arose from an ongoing collaboration, so that the project was within the scope of the graduate student's thesis. This…

Workshop on perinatal exposure to dioxin-like compounds. I. Summary.

PubMed Central

Lindström, G; Hooper, K; Petreas, M; Stephens, R; Gilman, A

1995-01-01

An international workshop reviewed 20 ongoing or recently completed studies of the effects of perinatal exposures to dioxins, dibenzofurans, and PCBs on the reproductive, endocrine, neurodevelopmental, and immune systems. Many of the observed effects are consistent with these compounds acting as "environmental hormones" or endocrine disrupters. This report summarizes the conclusions and future directions described at the workshop. PMID:7614935

DEVELOPMERNT OF A LOW-LEVEL ANALYTICAL METHOD FOR CO-PLANAR PCB CONGENERS IN SOIL/SEDIMENT MATRICES USING GC/ECD.

EPA Science Inventory

The method development is on-going in the Region 10 Laboratory. The conditions of the separation technique is complete. The MDLs have been determined to be between 3 to 6 ppt in marine sediment for co-planar PCB congeners #77; #81; #126 and #169. The procedure has been used fo...

Representing Urban Cultural Geography in Stabilization Operations: Analysis of a Social Network Representation in Pythagoras

DTIC Science & Technology

2008-06-01

improvement) may be necessary. Without this option, a complete economy with all ongoing transactions cannot be represented with the current version...during a time period of length h due to active I-actions perceived as good (respectively bad) is I IIG IG IG c h λ γξ µ = (respectively ( )1I I

Perceptual Learning Styles Modalities Utilizing the Multimodal Paired Associates Learning Test: An Analysis of Latinos Born in Central and South America

ERIC Educational Resources Information Center

Ramirez, Matias

2017-01-01

Businesses and Human Resources professionals face the ongoing challenge of continuously upskilling and developing employees. Changes to processes or procedures, changes in technology, changes in job functions, and updates or changes to compliance laws or regulations are all reasons that employees must attend and complete employer-developed…

Examining the Effectiveness of Dropout Prevention Practices and Their Implications for Intervention with Public School Students

ERIC Educational Resources Information Center

Pollack, Louisa

2010-01-01

Schools face the dilemma of transforming both the trend of students dropping out of school and the associated negative socioeconomic outcomes into a positive path of persistence and school completion. Despite ongoing efforts of the federal and state government, as well as those of the local school districts, this problem continues to burden the…

Prostate Cancer Biorepository Network

DTIC Science & Technology

2017-10-01

Department of the Army position, policy or decision unless so designated by other documentation. REPORT DOCUMENTATION PAGE Form Approved OMB No. 0704...clinical data including pathology and outcome data are annotated with the biospecimens. Specialized processing consists of tissue microarray design ...Months 1- 6): Completed in 1st quarter Task 5. Report on performance metrics: Ongoing (accrual reports are provided on quarterly basis) Task 6