Mentoring: A New Approach to Geography Teacher Preparation

ERIC Educational Resources Information Center

Bednarz, Sarah Witham; Bockenhauer, Mark H.; Walk, Fred H.

2005-01-01

Geography teacher preparation is an ongoing problem for the discipline. Changes in certification requirements and federal and state educational policies have diminished the role of colleges and universities in educating teachers. At the same time, geography education reform efforts have resulted in higher standards and an increased quantity of…

Systems approach to monitoring and evaluation guides scale up of the Standard Days Method of family planning in Rwanda.

PubMed

Igras, Susan; Sinai, Irit; Mukabatsinda, Marie; Ngabo, Fidele; Jennings, Victoria; Lundgren, Rebecka

2014-05-01

There is no guarantee that a successful pilot program introducing a reproductive health innovation can also be expanded successfully to the national or regional level, because the scaling-up process is complex and multilayered. This article describes how a successful pilot program to integrate the Standard Days Method (SDM) of family planning into existing Ministry of Health services was scaled up nationally in Rwanda. Much of the success of the scale-up effort was due to systematic use of monitoring and evaluation (M&E) data from several sources to make midcourse corrections. Four lessons learned illustrate this crucially important approach. First, ongoing M&E data showed that provider training protocols and client materials that worked in the pilot phase did not work at scale; therefore, we simplified these materials to support integration into the national program. Second, triangulation of ongoing monitoring data with national health facility and population-based surveys revealed serious problems in supply chain mechanisms that affected SDM (and the accompanying CycleBeads client tool) availability and use; new procedures for ordering supplies and monitoring stockouts were instituted at the facility level. Third, supervision reports and special studies revealed that providers were imposing unnecessary medical barriers to SDM use; refresher training and revised supervision protocols improved provider practices. Finally, informal environmental scans, stakeholder interviews, and key events timelines identified shifting political and health policy environments that influenced scale-up outcomes; ongoing advocacy efforts are addressing these issues. The SDM scale-up experience in Rwanda confirms the importance of monitoring and evaluating programmatic efforts continuously, using a variety of data sources, to improve program outcomes.

Systems approach to monitoring and evaluation guides scale up of the Standard Days Method of family planning in Rwanda

PubMed Central

Igras, Susan; Sinai, Irit; Mukabatsinda, Marie; Ngabo, Fidele; Jennings, Victoria; Lundgren, Rebecka

2014-01-01

There is no guarantee that a successful pilot program introducing a reproductive health innovation can also be expanded successfully to the national or regional level, because the scaling-up process is complex and multilayered. This article describes how a successful pilot program to integrate the Standard Days Method (SDM) of family planning into existing Ministry of Health services was scaled up nationally in Rwanda. Much of the success of the scale-up effort was due to systematic use of monitoring and evaluation (M&E) data from several sources to make midcourse corrections. Four lessons learned illustrate this crucially important approach. First, ongoing M&E data showed that provider training protocols and client materials that worked in the pilot phase did not work at scale; therefore, we simplified these materials to support integration into the national program. Second, triangulation of ongoing monitoring data with national health facility and population-based surveys revealed serious problems in supply chain mechanisms that affected SDM (and the accompanying CycleBeads client tool) availability and use; new procedures for ordering supplies and monitoring stockouts were instituted at the facility level. Third, supervision reports and special studies revealed that providers were imposing unnecessary medical barriers to SDM use; refresher training and revised supervision protocols improved provider practices. Finally, informal environmental scans, stakeholder interviews, and key events timelines identified shifting political and health policy environments that influenced scale-up outcomes; ongoing advocacy efforts are addressing these issues. The SDM scale-up experience in Rwanda confirms the importance of monitoring and evaluating programmatic efforts continuously, using a variety of data sources, to improve program outcomes. PMID:25276581

Efforts to improve international migration statistics: a historical perspective.

PubMed

Kraly, E P; Gnanasekaran, K S

1987-01-01

During the past decade, the international statistical community has made several efforts to develop standards for the definition, collection and publication of statistics on international migration. This article surveys the history of official initiatives to standardize international migration statistics by reviewing the recommendations of the International Statistical Institute, International Labor Organization, and the UN, and reports a recently proposed agenda for moving toward comparability among national statistical systems. Heightening awareness of the benefits of exchange and creating motivation to implement international standards requires a 3-pronged effort from the international statistical community. 1st, it is essential to continue discussion about the significance of improvement, specifically standardization, of international migration statistics. The move from theory to practice in this area requires ongoing focus by migration statisticians so that conformity to international standards itself becomes a criterion by which national statistical practices are examined and assessed. 2nd, the countries should be provided with technical documentation to support and facilitate the implementation of the recommended statistical systems. Documentation should be developed with an understanding that conformity to international standards for migration and travel statistics must be achieved within existing national statistical programs. 3rd, the call for statistical research in this area requires more efforts by the community of migration statisticians, beginning with the mobilization of bilateral and multilateral resources to undertake the preceding list of activities.

Supporting Excellence: A Framework for Developing, Implementing, and Sustaining a High-Quality District Curriculum. First Edition

ERIC Educational Resources Information Center

Council of the Great City Schools, 2017

2017-01-01

In the ongoing effort to improve instructional standards in our nation's urban public schools, the Council of the Great City Schools has released resources to help districts determine the quality and alignment of instructional materials at each grade level; to ensure that materials for English language learners are rigorous and aligned to district…

Advanced Solar Cell Testing and Characterization

NASA Technical Reports Server (NTRS)

Bailey, Sheila; Curtis, Henry; Piszczor, Michael

2005-01-01

The topic for this workshop stems from an ongoing effort by the photovoltaic community and U.S. government to address issues and recent problems associated with solar cells and arrays experienced by a number of different space systems. In April 2003, a workshop session was held at the Aerospace Space Power Workshop to discuss an effort by the Air Force to update and standardize solar cell and array qualification test procedures in an effort to ameliorate some of these problems. The organizers of that workshop session thought it was important to continue these discussions and present this information to the entire photovoltaic community. Thus, it was decided to include this topic as a workshop at the following SPRAT conference.

On the design of script languages for neural simulation.

PubMed

Brette, Romain

2012-01-01

In neural network simulators, models are specified according to a language, either specific or based on a general programming language (e.g. Python). There are also ongoing efforts to develop standardized languages, for example NeuroML. When designing these languages, efforts are often focused on expressivity, that is, on maximizing the number of model types than can be described and simulated. I argue that a complementary goal should be to minimize the cognitive effort required on the part of the user to use the language. I try to formalize this notion with the concept of "language entropy", and I propose a few practical guidelines to minimize the entropy of languages for neural simulation.

ASTM and ASME-BPE Standards--Complying with the Needs of the Pharmaceutical Industry.

PubMed

Huitt, William M

2011-01-01

Designing and building a pharmaceutical facility requires the owner, engineer of record, and constructor to be knowledgeable with regard to the industry codes and standards that apply to this effort. Up until 1997 there were no industry standards directed at the needs and requirements of the pharmaceutical industry. Prior to that time it was a patchwork effort at resourcing and adopting nonpharmaceutical-related codes and standards and then modifying them in order to meet the more stringent requirements of the Food and Drug Administration (FDA). In 1997 the American Society of Mechanical Engineers (ASME) published the first Bioprocessing Equipment (BPE) Standard. Through harmonization efforts this relatively new standard has brought together, scrutinized, and refined industry accepted methodologies together with FDA compliance requirements, and has established an American National Standard that provides a comprehensive set of standards that are integral to the pharmaceutical industry. This article describes various American National Standards, including those developed and published by the American Society for Testing and Materials (ASTM), and how they apply to the pharmaceutical industry. It goes on to discuss the harmonization effort that takes place between the various standards developers in an attempt to prevent conflicts and omissions between the many standards. Also included are examples of tables and figures taken from the ASME-BPE Standard. These examples provide the reader with insight to the relevant content of the ASME-BPE Standard. Designing and building a pharmaceutical facility requires the owner, engineer of record, and constructor to be knowledgeable with regard to the industry codes and standards that apply to this effort. Up until 1997 there were no industry standards directed at the needs and requirements of the pharmaceutical industry. Prior to that time it was a patchwork effort at resourcing and adopting nonpharmaceutical-related codes and standards and then modifying them in order to meet the more stringent requirements of the Food and Drug Administration (FDA). In 1997 the American Society of Mechanical Engineers (ASME) published the first Bioprocessing Equipment (BPE) Standard. In its initial development and ongoing maintenance it works with other American National Standards developers to harmonize the many standards associated with the design, engineering, and construction of bioprocessing facilities. This harmonization effort has established a comprehensive set of standards for the betterment of the pharmaceutical industry at large. This effort is, and will remain, very important as technology, along with new and improved product and processes, evolve into the future.

Cost Modeling for Space Telescope

NASA Technical Reports Server (NTRS)

Stahl, H. Philip

2011-01-01

Parametric cost models are an important tool for planning missions, compare concepts and justify technology investments. This paper presents on-going efforts to develop single variable and multi-variable cost models for space telescope optical telescope assembly (OTA). These models are based on data collected from historical space telescope missions. Standard statistical methods are used to derive CERs for OTA cost versus aperture diameter and mass. The results are compared with previously published models.

Status of the AIAA Modeling and Simulation Format Standard

NASA Technical Reports Server (NTRS)

Jackson, E. Bruce; Hildreth, Bruce L.

2008-01-01

The current draft AIAA Standard for flight simulation models represents an on-going effort to improve the productivity of practitioners of the art of digital flight simulation (one of the original digital computer applications). This initial release provides the capability for the efficient representation and exchange of an aerodynamic model in full fidelity; the DAVE-ML format can be easily imported (with development of site-specific import tools) in an unambiguous way with automatic verification. An attractive feature of the standard is the ability to coexist with existing legacy software or tools. The draft Standard is currently limited in scope to static elements of dynamic flight simulations; however, these static elements represent the bulk of typical flight simulation mathematical models. It is already seeing application within U.S. and Australian government agencies in an effort to improve productivity and reduce model rehosting overhead. An existing tool allows import of DAVE-ML models into a popular simulation modeling and analysis tool, and other community-contributed tools and libraries can simplify the use of DAVE-ML compliant models at compile- or run-time of high-fidelity flight simulation.

Quality control and assurance for validation of DOS/I measurements

NASA Astrophysics Data System (ADS)

Cerussi, Albert; Durkin, Amanda; Kwong, Richard; Quang, Timothy; Hill, Brian; Tromberg, Bruce J.; MacKinnon, Nick; Mantulin, William W.

2010-02-01

Ongoing multi-center clinical trials are crucial for Biophotonics to gain acceptance in medical imaging. In these trials, quality control (QC) and assurance (QA) are key to success and provide "data insurance". Quality control and assurance deal with standardization, validation, and compliance of procedures, materials and instrumentation. Specifically, QC/QA involves systematic assessment of testing materials, instrumentation performance, standard operating procedures, data logging, analysis, and reporting. QC and QA are important for FDA accreditation and acceptance by the clinical community. Our Biophotonics research in the Network for Translational Research in Optical Imaging (NTROI) program for breast cancer characterization focuses on QA/QC issues primarily related to the broadband Diffuse Optical Spectroscopy and Imaging (DOS/I) instrumentation, because this is an emerging technology with limited standardized QC/QA in place. In the multi-center trial environment, we implement QA/QC procedures: 1. Standardize and validate calibration standards and procedures. (DOS/I technology requires both frequency domain and spectral calibration procedures using tissue simulating phantoms and reflectance standards, respectively.) 2. Standardize and validate data acquisition, processing and visualization (optimize instrument software-EZDOS; centralize data processing) 3. Monitor, catalog and maintain instrument performance (document performance; modularize maintenance; integrate new technology) 4. Standardize and coordinate trial data entry (from individual sites) into centralized database 5. Monitor, audit and communicate all research procedures (database, teleconferences, training sessions) between participants ensuring "calibration". This manuscript describes our ongoing efforts, successes and challenges implementing these strategies.

Assessment of Offshore Wind System Design, Safety, and Operation Standards

DOE Office of Scientific and Technical Information (OSTI.GOV)

Sirnivas, Senu; Musial, Walt; Bailey, Bruce

This report is a deliverable for a project sponsored by the U.S. Department of Energy (DOE) entitled National Offshore Wind Energy Resource and Design Data Campaign -- Analysis and Collaboration (contract number DE-EE0005372; prime contractor -- AWS Truepower). The project objective is to supplement, facilitate, and enhance ongoing multiagency efforts to develop an integrated national offshore wind energy data network. The results of this initiative are intended to 1) produce a comprehensive definition of relevant met-ocean resource assets and needs and design standards, and 2) provide a basis for recommendations for meeting offshore wind energy industry data and design certificationmore » requirements.« less

Properties and Units in the Clinical Laboratory Sciences. IX. Properties and Units in Trace Elements (IUPAC-IFCC Technical report 1997). International Union of Pure and Applied Chemistry and International Federation of Clinical Chemistry. rita.cornelis@rug.ac.be.

PubMed

Cornelis, R; Fuentes-Arderiu, X; Bruunshuus, I; Templeton, D

1997-12-10

This document is the first recommendation on the presentation of trace elements and their values in clinical laboratory sciences from IFCC and IUPAC. It forms part of the ongoing effort to standardize requests and reporting of laboratory data for transmission across cultural and linguistic domains, without attempting to standardize the language used by clinicians and laboratory practitioners. Subsequent documents deal with syntax, kinds-of-property, and properties and units used in other areas of clinical laboratory sciences.

Bridging the Gap: Adaptive Games and Student-Centered VLEs

NASA Astrophysics Data System (ADS)

Del Blanco, Ángel; Torrente, Javier; Moreno-Ger, Pablo; Fernández-Manjón, Baltasar

The widely used e-learning technology is facing new challenges such as how to produce student-centered systems that can be adapted to the needs of each student. Those objectives should be met in a standard compliant way to simplify general adoption. In this context, educational videogames are proposed as an ideal medium to facilitate adaptation and tracking of the students’ performance for assessment purposes. However, there are still barriers between the gaming and e-learning worlds preventing their mutual interaction. In this paper we propose a middleware to bridge this gap, integrating adaptive educational videogames in e-learning environments with a special focus on the ongoing standardization efforts.

Data Friction Meets Social Friction: Challenges for standardization in emerging fields of geoscience

NASA Astrophysics Data System (ADS)

Darch, P. T.

2017-12-01

Many interdisciplinary endeavors in the geosciences occur in emergent scientific fields. These fields are often characterized by heterogeneity of methods for production and collection of data, and by data scarcity. This paper presents findings about processes of methods standardization from a long-term case study of an emergent, data-scarce field, the deep subseafloor biosphere. Researchers come from many physical and life science backgrounds to study interactions between microbial life in the seafloor and the physical environment they inhabit. Standardization of methods for collecting data promises multiple benefits to this field, including: Addressing data scarcity through enabling greater data reuse and promoting better interoperability with large scale infrastructures; Fostering stronger collaborative links between researchers distributed across institutions and backgrounds. Ongoing standardization efforts in the field do not only involve scientific judgments about which among a range of methods is most efficient, least biased, or most reliable. Instead, these efforts also encounter multiple difficult social challenges, including: Lack of agreed upon criteria about how to judge competing methods: should efficiency, bias, or reliability take priority?; Lack of resources to carry out the work necessary to determine standards, particularly acute in emergent fields; Concerns that standardization is premature in such a new field, foreclosing the possibility of better methods being developed in the future; Concerns that standardization could prematurely shut down important scientific debates; Concerns among some researchers that their own work may become obsolete should the methods chosen as standard be different from their own. The success of these standardization efforts will depend on addressing both scientific and social dimensions, to ensure widespread acceptance among researchers in the field.

Standardization and quality management in next-generation sequencing.

PubMed

Endrullat, Christoph; Glökler, Jörn; Franke, Philipp; Frohme, Marcus

2016-09-01

DNA sequencing continues to evolve quickly even after > 30 years. Many new platforms suddenly appeared and former established systems have vanished in almost the same manner. Since establishment of next-generation sequencing devices, this progress gains momentum due to the continually growing demand for higher throughput, lower costs and better quality of data. In consequence of this rapid development, standardized procedures and data formats as well as comprehensive quality management considerations are still scarce. Here, we listed and summarized current standardization efforts and quality management initiatives from companies, organizations and societies in form of published studies and ongoing projects. These comprise on the one hand quality documentation issues like technical notes, accreditation checklists and guidelines for validation of sequencing workflows. On the other hand, general standard proposals and quality metrics are developed and applied to the sequencing workflow steps with the main focus on upstream processes. Finally, certain standard developments for downstream pipeline data handling, processing and storage are discussed in brief. These standardization approaches represent a first basis for continuing work in order to prospectively implement next-generation sequencing in important areas such as clinical diagnostics, where reliable results and fast processing is crucial. Additionally, these efforts will exert a decisive influence on traceability and reproducibility of sequence data.

Interactive effects in transfer-appropriate processing for event-based prospective memory: the roles of effort, ongoing task, and PM cue properties.

PubMed

Abney, Drew H; McBride, Dawn M; Petrella, Samantha N

2013-10-01

Past studies (e.g., Marsh, Hicks, & Cook Journal of Experimental Psychology: Learning, Memory, and Cognition 31:68-75, 2005; Meiser & Schult European Journal of Cognitive Psychology 20:290-311, 2008) have shown that transfer-appropriate processing (TAP) effects in event-based prospective memory (PM) depend on the effort directed toward the ongoing task. In the present study, we addressed mixed findings from these studies and examined monitoring in TAP and transfer-inappropriate processing (TIP) conditions. In two experiments, a semantic or orthographic ongoing task was paired with a PM cue that either was matched in processing (TAP) or did not match in processing (TIP). Within each condition, effort was varied across trials. The results indicated that PM accuracy was higher in TAP than in TIP conditions, regardless of effort condition, supporting the findings reported by Meiser and Schult. Ex-Gaussian functions were fit to the mean reaction times (cf. Brewer Journal of Psychology 219:117-124, 2011) in order to examine monitoring across conditions. The analysis of distributional skew (τ parameter) showed sensitivity to ongoing task instructions and properties of the PM cues. These results support Meiser and Schult's suggestion that TIP conditions require more attentional processing, and they also afford novel discussion on the interactive effects of ongoing task condition, PM cue properties, and manipulations of effort.

Reinventing the Wheel: One Program's Approach to Redesign of Didactic Courses.

PubMed

Hudak, Nicholas M; Scott, Victoria; Spear, Sherrie B; Hills, Karen J

2015-12-01

Curriculum and course redesign are expected and intentional efforts in health professions education. For physician assistant (PA) education, ongoing program self-assessment is a required accreditation standard and may guide deliberate changes within curriculum. The purpose of this article is to describe one PA program’s approach to the redesign of 4 courses into 3 courses that span the entire didactic phase. Significant lessons learned include the importance of planning ahead, identifying key players, documenting the process as part of ongoing self-assessment, competency mapping, and being prepared to make real-time modifications and changes based on course evaluations and faculty feedback. Our approach and guiding principles to the successful redesign of the didactic courses may provide both established and new PA educational programs with useful methods to apply in their own unique curricula.

The big hurt: Trauma system funding in today's health care environment.

PubMed

Geehan, Douglas

2010-01-01

Trauma systems provide effective care of the injured patient but require major financial costs in readiness and availability of the extensive trauma team and specialized equipment. Traditional billing and collection practices do not fully recoup these costs. Effective use of the standard billing system is vital to the stability of a trauma system; however, a system wide funding mechanism provides an optimal, stable foundation. Efforts to provide sustainable trauma system funding are ongoing. Numerous state initiatives have been successful in funding trauma systems but a universal solution has yet to be found.

On the Relationship Between Effort Toward an Ongoing Task and Cue Detection in Event-Based Prospective Memory

ERIC Educational Resources Information Center

Marsh, Richard L.; Hicks, Jason L.; Cook, Gabriel I.

2005-01-01

In recent theories of event-based prospective memory, researchers have debated what degree of resources are necessary to identify a cue as related to a previously established intention. In order to simulate natural variations in attention, the authors manipulated effort toward an ongoing cognitive task in which intention-related cues were embedded…

Clinical utility of cerebrospinal fluid biomarkers in the diagnosis of early Alzheimer’s disease

PubMed Central

Blennow, Kaj; Dubois, Bruno; Fagan, Anne M.; Lewczuk, Piotr; de Leon, Mony J.; Hampel, Harald

2015-01-01

Several potential disease-modifying drugs for Alzheimer’s disease (AD) have failed to show any effect on disease progression in clinical trials, conceivably because the AD subjects are already too advanced to derive clinical benefit from treatment and because diagnosis based on clinical criteria alone introduces a high misdiagnosis rate. Thus, well-validated biomarkers for early detection and accurate diagnosis are crucial. Low cerebrospinal fluid (CSF) concentrations of the amyloid-β (Aβ1-42) peptide, in combination with high total tau and phosphorylated tau, are sensitive and specific biomarkers highly predictive of progression to AD dementia in patients with mild cognitive impairment. However, interlaboratory variations in the results seen with currently available immunoassays are of concern. Recent worldwide standardization efforts and quality control programs include standard operating procedures for both preanalytical (e.g., lumbar puncture and sample handling) and analytical (e.g., preparation of calibration curve) procedures. Efforts are also ongoing to develop highly reproducible assays on fully automated instruments. These global standardization and harmonization measures will provide the basis for the generalized international application of CSF bio-markers for both clinical trials and routine clinical diagnosis of AD. PMID:24795085

Employment rights of people with diabetes: changing technology and changing law.

PubMed

Griffin, John W

2013-03-01

Though the treatment of diabetes has advanced remarkably, the law and many employers have not always kept pace. New insulins, delivery systems, and monitoring systems give people with diabetes exceptional control over their blood sugar and virtually eliminate serious complications such as hypoglycemia and hyperglycemia. Changes in the law, particularly the Americans with Disabilities Act and its 2008 amendments, give people with diabetes greater rights and employment opportunities than ever before. Despite these advances, many employers continue to use blanket bans or ill-considered standards to bar people with diabetes. Efforts to break down these remaining barriers are ongoing through employee litigation and through the American Diabetes Association's collaboration with entities that set occupational standards. © 2013 Diabetes Technology Society.

Maintaining the momentum of Open Search in Earth Science Data discovery

NASA Astrophysics Data System (ADS)

Newman, D. J.; Lynnes, C.

2013-12-01

Federated Search for Earth Observation data has been a hallmark of EOSDIS (Earth Observing System Data and Information System) for two decades. Originally, the EOSDIS Version 0 system provided both data-collection-level and granule/file-level search in the mid 1990s with EOSDIS-specific socket protocols and message formats. Since that time, the advent of several standards has helped to simplify EOSDIS federated search, beginning with HTTP as the transfer protocol. Most recently, OpenSearch (www.opensearch.org) was employed for the EOS Clearinghouse (ECHO), based on a set of conventions that had been developed within the Earth Science Information Partners (ESIP) Federation. The ECHO OpenSearch API has evolved to encompass the ESIP RFC and the Open Geospatial Consortium (OGC) Open Search standard. Uptake of the ECHO Open Search API has been significant and has made ECHO accessible to client developers that found the previous ECHO SOAP API and current REST API too complex. Client adoption of the OpenSearch API appears to be largely driven by the simplicity of the OpenSearch convention. This simplicity is thus important to retain as the standard and convention evolve. For example, ECHO metrics indicate that the vast majority of ECHO users favor the following search criteria when using the REST API, - Spatial - bounding box, polygon, line and point - Temporal - start and end time - Keywords - free text Fewer than 10% of searches use additional constraints, particularly those requiring a controlled vocabulary, such as instrument, sensor, etc. This suggests that ongoing standardization efforts around OpenSearch usage for Earth Observation data may be more productive if oriented toward improving support for the Spatial, Temporal and Keyword search aspects. Areas still requiring improvement include support of - Concrete requirements for keyword constraints - Phrasal search for keyword constraints - Temporal constraint relations - Terminological symmetry between search URLs and response documents for both temporal and spatial terms - Best practices for both servers and clients. Over the past year we have seen several ongoing efforts to further standardize Open Search in the earth science domain such as, - Federation of Earth Science Information Partners (ESIP) - Open Geospatial Consortium (OGC) - Committee on Earth Observation Satellites (CEOS)

Collaborative Data Publication Utilizing the Open Data Repository's (ODR) Data Publisher

NASA Technical Reports Server (NTRS)

Stone, N.; Lafuente, B.; Bristow, T.; Keller, R. M.; Downs, R. T.; Blake, D.; Fonda, M.; Dateo, C.; Pires, A.

2017-01-01

Introduction: For small communities in diverse fields such as astrobiology, publishing and sharing data can be a difficult challenge. While large, homogenous fields often have repositories and existing data standards, small groups of independent researchers have few options for publishing standards and data that can be utilized within their community. In conjunction with teams at NASA Ames and the University of Arizona, the Open Data Repository's (ODR) Data Publisher has been conducting ongoing pilots to assess the needs of diverse research groups and to develop software to allow them to publish and share their data collaboratively. Objectives: The ODR's Data Publisher aims to provide an easy-to-use and implement software tool that will allow researchers to create and publish database templates and related data. The end product will facilitate both human-readable interfaces (web-based with embedded images, files, and charts) and machine-readable interfaces utilizing semantic standards. Characteristics: The Data Publisher software runs on the standard LAMP (Linux, Apache, MySQL, PHP) stack to provide the widest server base available. The software is based on Symfony (www.symfony.com) which provides a robust framework for creating extensible, object-oriented software in PHP. The software interface consists of a template designer where individual or master database templates can be created. A master database template can be shared by many researchers to provide a common metadata standard that will set a compatibility standard for all derivative databases. Individual researchers can then extend their instance of the template with custom fields, file storage, or visualizations that may be unique to their studies. This allows groups to create compatible databases for data discovery and sharing purposes while still providing the flexibility needed to meet the needs of scientists in rapidly evolving areas of research. Research: As part of this effort, a number of ongoing pilot and test projects are currently in progress. The Astrobiology Habitable Environments Database Working Group is developing a shared database standard using the ODR's Data Publisher and has a number of example databases where astrobiology data are shared. Soon these databases will be integrated via the template-based standard. Work with this group helps determine what data researchers in these diverse fields need to share and archive. Additionally, this pilot helps determine what standards are viable for sharing these types of data from internally developed standards to existing open standards such as the Dublin Core (http://dublincore.org) and Darwin Core (http://rs.twdg.org) metadata standards. Further studies are ongoing with the University of Arizona Department of Geosciences where a number of mineralogy databases are being constructed within the ODR Data Publisher system. Conclusions: Through the ongoing pilots and discussions with individual researchers and small research teams, a definition of the tools desired by these groups is coming into focus. As the software development moves forward, the goal is to meet the publication and collaboration needs of these scientists in an unobtrusive and functional way.

Performance standards for urban search and rescue robots

NASA Astrophysics Data System (ADS)

Messina, Elena; Jacoff, Adam

2006-05-01

In this paper, we describe work in performance standards for urban search and rescue (USAR) robots begun in 2004 by the Department of Homeland Security. This program is being coordinated by the National Institute of Standards and Technology and will result in consensus standards developed through ASTM International, under the Operational Equipment Subcommittee of their Homeland Security Committee. The first phase of the program involved definition of requirements by subject matter experts. Responders participated in a series of workshops to identify deployment categories for robots, performance categories, and ranges of acceptable or target performance in the various categories. Over one hundred individual requirements were identified, within main categories such as Human-System Interaction, Logistics, Operating Environment, and System (which includes Chassis, Communications, Mobility, Payload, Power, and Sensing). To ensure that the robot developers and eventual end users work closely together, "responders meet robots" events at situationally relevant sites are being held to refine and extend the performance requirements and develop standard test methods. The results of these standard performance tests will be captured in a compendium of existing and developmental robots with classifications and descriptors to differentiate particular robotic capabilities. This, along with ongoing efforts to categorize situational USAR constraints such as building collapse types or the presence of hazardous materials, will help responders match particular robotic capabilities to response needs. In general, these efforts will enable responders to effectively use robotic tools to enhance their effectiveness while reducing risk to personnel during disasters.

The Need For Ongoing Surveys About Physician Practice Costs.

PubMed

Berk, Marc L

2016-09-01

Physicians continue to be the subject of many survey efforts asking them about a wide range of issues including training, retirement plans, satisfaction with practice, practice organization, and practice costs. The resources dedicated to the collection of different types of data have changed over time. Collection efforts have both expanded and contracted. Here I discuss this phenomenon for several types of physician surveys, with particular focus on the reduction in ongoing survey efforts about physician practice costs. The diminution of efforts to collect information about these costs represents an important challenge since the lack of timely, high-quality data could impair the correct calculation of reimbursement rates. Project HOPE—The People-to-People Health Foundation, Inc.

Lightweight Damage Tolerant Radiators for In-Space Nuclear Electric Power and Propulsion

NASA Technical Reports Server (NTRS)

Craven, Paul; SanSoucie, Michael P.; Tomboulian, Briana; Rogers, Jan; Hyers, Robert

2014-01-01

Nuclear electric propulsion (NEP) is a promising option for high-speed in-space travel due to the high energy density of nuclear power sources and efficient electric thrusters. Advanced power conversion technologies for converting thermal energy from the reactor to electrical energy at high operating temperatures would benefit from lightweight, high temperature radiator materials. Radiator performance dictates power output for nuclear electric propulsion systems. Pitch-based carbon fiber materials have the potential to offer significant improvements in operating temperature and mass. An effort at the NASA Marshall Space Flight Center to show that woven high thermal conductivity carbon fiber mats can be used to replace standard metal and composite radiator fins to dissipate waste heat from NEP systems is ongoing. The goals of this effort are to demonstrate a proof of concept, to show that a significant improvement of specific power (power/mass) can be achieved, and to develop a thermal model with predictive capabilities. A description of this effort is presented.

Petroselinum crispum extract attenuates hepatic steatosis in rats fed with fructose enriched diet.

PubMed

Nair, V Yuneesha; Balakrishanan, N; Antony Santiago, J Victor

2015-01-01

Non alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and ongoing research efforts are focused on understanding the underlying pathophysiology of hepatic steatosis with the anticipation that these efforts will identify novel therapeutic targets. This study investigated the Petroselinum crispum extract in hepatic steatosis in rats fed with fructose enriched diet. Rats were divided into the 4 groups: Group 1 rats received standard pellet diet with corn starch for the entire experimental period of 8 weeks. Group 2 rats received standard pellet diet and 2 gm/kg body weight crude Parsley leaf ethanol extract for the entire experimental period of 8 weeks. Group 3 rats received modified fructose diet. Group 4 rats received modified fructose diet and 2gm/kg crude Parsley leaf ethanol extract. Hepatic function and structure was evaluated in these rats. Modified fructose diet produced dyslipidemia, hepatic steatosis and infiltration of inflammatory cells in the liver and higher plasma hepatic markers. Petroselinum crispum extract reversed metabolic changes such as abnormal crispum extract attenuated chronic changes in modified fructose diet induced NAFLD (Tab. 2, Fig. 3, Ref. 43).

RELAP-7 Theory Manual

DOE Office of Scientific and Technical Information (OSTI.GOV)

Berry, Ray Alden; Zou, Ling; Zhao, Haihua

This document summarizes the physical models and mathematical formulations used in the RELAP-7 code. In summary, the MOOSE based RELAP-7 code development is an ongoing effort. The MOOSE framework enables rapid development of the RELAP-7 code. The developmental efforts and results demonstrate that the RELAP-7 project is on a path to success. This theory manual documents the main features implemented into the RELAP-7 code. Because the code is an ongoing development effort, this RELAP-7 Theory Manual will evolve with periodic updates to keep it current with the state of the development, implementation, and model additions/revisions.

Commercial Video Games As Therapy: A New Research Agenda to Unlock the Potential of a Global Pastime.

PubMed

Colder Carras, Michelle; Van Rooij, Antonius J; Spruijt-Metz, Donna; Kvedar, Joseph; Griffiths, Mark D; Carabas, Yorghos; Labrique, Alain

2017-01-01

Emerging research suggests that commercial, off-the-shelf video games have potential applications in preventive and therapeutic medicine. Despite these promising findings, systematic efforts to characterize and better understand this potential have not been undertaken. Serious academic study of the therapeutic potential of commercial video games faces several challenges, including a lack of standard terminology, rapidly changing technology, societal attitudes toward video games, and understanding and accounting for complex interactions between individual, social, and cultural health determinants. As a vehicle to launch a new interdisciplinary research agenda, the present paper provides background information on the use of commercial video games for the prevention, treatment, and rehabilitation of mental and other health conditions, and discusses ongoing grassroots efforts by online communities to use video games for healing and recovery.

Commercial Video Games As Therapy: A New Research Agenda to Unlock the Potential of a Global Pastime

PubMed Central

Colder Carras, Michelle; Van Rooij, Antonius J.; Spruijt-Metz, Donna; Kvedar, Joseph; Griffiths, Mark D.; Carabas, Yorghos; Labrique, Alain

2018-01-01

Emerging research suggests that commercial, off-the-shelf video games have potential applications in preventive and therapeutic medicine. Despite these promising findings, systematic efforts to characterize and better understand this potential have not been undertaken. Serious academic study of the therapeutic potential of commercial video games faces several challenges, including a lack of standard terminology, rapidly changing technology, societal attitudes toward video games, and understanding and accounting for complex interactions between individual, social, and cultural health determinants. As a vehicle to launch a new interdisciplinary research agenda, the present paper provides background information on the use of commercial video games for the prevention, treatment, and rehabilitation of mental and other health conditions, and discusses ongoing grassroots efforts by online communities to use video games for healing and recovery. PMID:29403398

A focal plane metrology system and PSF centroiding experiment

NASA Astrophysics Data System (ADS)

Li, Haitao; Li, Baoquan; Cao, Yang; Li, Ligang

2016-10-01

In this paper, we present an overview of a detector array equipment metrology testbed and a micro-pixel centroiding experiment currently under development at the National Space Science Center, Chinese Academy of Sciences. We discuss on-going development efforts aimed at calibrating the intra-/inter-pixel quantum efficiency and pixel positions for scientific grade CMOS detector, and review significant progress in achieving higher precision differential centroiding for pseudo star images in large area back-illuminated CMOS detector. Without calibration of pixel positions and intrapixel response, we have demonstrated that the standard deviation of differential centroiding is below 2.0e-3 pixels.

Improving Patient Safety with X-Ray and Anesthesia Machine Ventilator Synchronization: A Medical Device Interoperability Case Study

NASA Astrophysics Data System (ADS)

Arney, David; Goldman, Julian M.; Whitehead, Susan F.; Lee, Insup

When a x-ray image is needed during surgery, clinicians may stop the anesthesia machine ventilator while the exposure is made. If the ventilator is not restarted promptly, the patient may experience severe complications. This paper explores the interconnection of a ventilator and simulated x-ray into a prototype plug-and-play medical device system. This work assists ongoing interoperability framework development standards efforts to develop functional and non-functional requirements and illustrates the potential patient safety benefits of interoperable medical device systems by implementing a solution to a clinical use case requiring interoperability.

CCSDS - Advancing Spaceflight Technology for International Collaboration

NASA Technical Reports Server (NTRS)

Kearney, Mike; Kiely, Aaron; Yeh, Penshu; Gerner, Jean-Luc; Calzolari, Gian-Paolo; Gifford, Kevin; Merri, Mario; Weiss, Howard

2010-01-01

The Consultative Committee for Space Data Systems (CCSDS) has been developing data and communications standards since 1982, with the objective of providing interoperability for enabling international collaboration for spaceflight missions. As data and communications technology has advanced, CCSDS has progressed to capitalize on existing products when available and suitable for spaceflight, and to develop innovative new approaches when available products fail. The current scope of the CCSDS architecture spans the end-to-end data architecture of a spaceflight mission, with ongoing efforts to develop and standardize cutting-edge technology. This manuscript describes the overall architecture, the position of CCSDS in the standards and international mission community, and some CCSDS processes. It then highlights in detail several of the most interesting and critical technical areas in work right now, and how they support collaborative missions. Special topics include: Delay/Disruption Tolerant Networking (DTN), Asynchronous Message Service (AMS), Multispectral/Hyperspectral Data Compression (MHDC), Coding and Synchronization, Onboard Wireless, Spacecraft Monitor and Control, Navigation, Security, and Time Synchronization/Correlation. Broad international participation in development of CCSDS standards is encouraged.

Evaluation of a medication order writing standards policy in a regional health authority.

PubMed

Raymond, Colette B; Sproll, Barbara; Coates, Jan; Woloschuk, Donna M M

2013-09-01

The Winnipeg Regional Health Authority (WRHA) implemented a medication order writing standards (MOWS) policy (including banned abbreviations) to improve patient safety. Widespread educational campaigns and direct prescriber feedback were implemented. We audited orders within the WRHA from 2005 to 2009 and surveyed all WRHA staff in 2011 about the policy and suggestions for improving education and compliance. Overall, orders containing banned abbreviations, acronyms or symbols numbered 2261/8565 (26.4%) preimplementation. After WRHA-wide didactic education, the proportion declined to 1358/5461 (24.9%) (p = 0.043) and then, with targeted prescriber feedback, to 1186/6198 (19.1%) (p < 0.0001). A survey of 723 employees showed frequent violations of the MOWS, despite widespread knowledge of the policy. Respondents supported ongoing efforts to enforce the policy within the WRHA. Nonprescribers were significantly more likely than prescribers to agree with statements regarding enhancing compliance by defining prescriber/transcriber responsibilities and placing sanctions on noncompliant prescribers. Education, raising general awareness and targeted feedback to prescribers alone are insufficient to ensure compliance with MOWS policies. WRHA staff supported ongoing communication, improved tools such as compliant preprinted orders and reporting and feedback about medication incidents. A surprising number of respondents supported placing sanctions on noncompliant prescribers. Serial audits and targeted interventions such as direct prescriber feedback improve prescription quality in inpatient hospital settings. Education plus direct prescriber feedback had a greater impact than education alone on improving compliance with a MOWS policy. Future efforts at the WRHA to improve compliance will require an expanded focus on incentives, resources and development of action plans that involve all affected staff, not just prescribers. Plans include continued advertising, MOWS summaries in all charts, all-staff education, reminders and exploration of sustainable interventions for targeted feedback for prescribers.

77 FR 70123 - Retrospective Review Under Executive Order 13579

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-23

... ongoing review of its regulations related to the recent events at the Fukushima Dai-ichi Nuclear Power Plant in Japan; and (5) the NRC's previous and ongoing efforts to update its regulations in a systematic...

Generic extravehicular (EVA) and telerobot task primitives for analysis, design, and integration. Version 1.0: Reference compilation for the EVA and telerobotics communities

NASA Technical Reports Server (NTRS)

Smith, Jeffrey H.; Drews, Michael

1990-01-01

The results are described of an effort to establish commonality and standardization of generic crew extravehicular (crew-EVA) and telerobotic task analysis primitives used for the study of spaceborne operations. Although direct crew-EVA plans are the most visible output of spaceborne operations, significant ongoing efforts by a wide variety of projects and organizations also require tools for estimation of crew-EVA and telerobotic times. Task analysis tools provide estimates for input to technical and cost tradeoff studies. A workshop was convened to identify the issues and needs to establish a common language and syntax for task analysis primitives. In addition, the importance of such a syntax was shown to have precedence over the level to which such a syntax is applied. The syntax, lists of crew-EVA and telerobotic primitives, and the data base in diskette form are presented.

25 CFR 1000.396 - Does a Tribe/Consortium have additional ongoing requirements to maintain minimum standards for...

Code of Federal Regulations, 2013 CFR

2013-04-01

... 25 Indians 2 2013-04-01 2013-04-01 false Does a Tribe/Consortium have additional ongoing requirements to maintain minimum standards for Tribe/Consortium management systems? 1000.396 Section 1000.396... Miscellaneous Provisions § 1000.396 Does a Tribe/Consortium have additional ongoing requirements to maintain...

NASA's current activities in free space optical communications

NASA Astrophysics Data System (ADS)

Edwards, Bernard L.

2017-11-01

NASA and other space agencies around the world are currently developing free space optical communication systems for both space-to-ground links and space-to-space links. This paper provides an overview of NASA's current activities in free space optical communications with a focus on Near Earth applications. Activities to be discussed include the Lunar Laser Communication Demonstration, the Laser Communications Relay Demonstration, and the commercialization of the underlying technology. The paper will also briefly discuss ongoing efforts and studies for Deep Space optical communications. Finally the paper will discuss the development of international optical communication standards within the Consultative Committee for Space Data Systems.

Beyond reputation: debate on the role of corporate influence in occupational and environmental medicine.

PubMed

Bohme, Susanna Rankin; Egilman, David

2008-01-01

In his article in this issue, Tee Guidotti casts recent works addressing corporate influence on occupational medicine as "collective act[s] of disparagement ... undertaken ... for political reasons." We move beyond the question of reputation to address key conflicts in the history of occupational medicine, including the American Occupational Medical Association's historical role in weakening the beryllium standard and the American College of Occupational and Environmental Medicine's recent efforts to limit the extent of the Family Medical Leave Act. The corporate practice of externalizing health and safety costs makes industry influence an important ongoing topic of debate in occupational and environmental medicine.

Lightweight Radiator for in Space Nuclear Electric Propulsion

NASA Technical Reports Server (NTRS)

Craven, Paul; Tomboulian, Briana; SanSoucie, Michael

2014-01-01

Nuclear electric propulsion (NEP) is a promising option for high-speed in-space travel due to the high energy density of nuclear fission power sources and efficient electric thrusters. Advanced power conversion technologies may require high operating temperatures and would benefit from lightweight radiator materials. Radiator performance dictates power output for nuclear electric propulsion systems. Game-changing propulsion systems are often enabled by novel designs using advanced materials. Pitch-based carbon fiber materials have the potential to offer significant improvements in operating temperature, thermal conductivity, and mass. These properties combine to allow advances in operational efficiency and high temperature feasibility. An effort at the NASA Marshall Space Flight Center to show that woven high thermal conductivity carbon fiber mats can be used to replace standard metal and composite radiator fins to dissipate waste heat from NEP systems is ongoing. The goals of this effort are to demonstrate a proof of concept, to show that a significant improvement of specific power (power/mass) can be achieved, and to develop a thermal model with predictive capabilities making use of constrained input parameter space. A description of this effort is presented.

Integration of technology-based outcome measures in clinical trials of Parkinson and other neurodegenerative diseases.

PubMed

Artusi, Carlo Alberto; Mishra, Murli; Latimer, Patricia; Vizcarra, Joaquin A; Lopiano, Leonardo; Maetzler, Walter; Merola, Aristide; Espay, Alberto J

2018-01-01

We sought to review the landscape of past, present, and future use of technology-based outcome measures (TOMs) in clinical trials of neurodegenerative disorders. We systematically reviewed PubMed and ClinicalTrials.gov for published and ongoing clinical trials in neurodegenerative disorders employing TOMs. In addition, medical directors of selected pharmaceutical companies were surveyed on their companies' ongoing efforts and future plans to integrate TOMs in clinical trials as primary, secondary, or exploratory endpoints. We identified 164 published clinical trials indexed in PubMed that used TOMs as outcome measures in Parkinson disease (n = 132) or other neurodegenerative disorders (n = 32). The ClinicalTrials.gov search yielded 42 clinical trials using TOMs, representing 2.7% of ongoing trials. Sensor-based technology accounted for over 75% of TOMs applied. Gait and physical activity were the most common targeted domains. Within the next 5 years, 83% of surveyed pharmaceutical companies engaged in neurodegenerative disorders plan to deploy TOMs in clinical trials. Although promising, TOMs are underutilized in clinical trials of neurodegenerative disorders. Validating relevant endpoints, standardizing measures and procedures, establishing a single platform for integration of data and algorithms from different devices, and facilitating regulatory approvals should advance TOMs integration into clinical trials. Copyright © 2017 Elsevier Ltd. All rights reserved.

Vulnerability of schools to floods in Nyando River catchment, Kenya.

PubMed

Ochola, Samuel O; Eitel, Bernhard; Olago, Daniel O

2010-07-01

This paper assesses the vulnerability of schools to floods in the Nyando River catchment (3,600 km(2)) in western Kenya and identifies measures needed to reduce this vulnerability. It surveys 130 schools in the lower reaches, where flooding is a recurrent phenomenon. Of the primary schools assessed, 40% were vulnerable, 48% were marginally vulnerable and 12% were not vulnerable. Of the secondary schools, 8% were vulnerable, 73% were marginally vulnerable and 19% were not vulnerable. Vulnerability to floods is due to a lack of funds, poor building standards, local topography, soil types and inadequate drainage. The Constituencies Development Fund (CDF), established in 2003, provides financial support to cover school construction and reconstruction costs; CDF Committees are expected to adopt school building standards. In an effort to promote safe and resilient construction and retrofitting to withstand floods, this paper presents vulnerability reduction strategies and recommendations for incorporating minimum standards in the on-going Primary School Infrastructure Programme Design.

Treatment options after sorafenib failure in patients with hepatocellular carcinoma

PubMed Central

Dika, Imane El

2017-01-01

Second line therapy after failure of sorafenib continues to be under study. Prognosis of hepatocellular carcinoma is measured in months, with median overall survival reaching 10.7 months with sorafenib. Because of the modest net benefit sorafenib has contributed, and rising incidence of hepatocellular carcinoma in the world, continued efforts are ongoing to look for efficient upfront, second line, or combination therapies. Herein we review the most relevant to date published literature on treatment options beyond sorafenib, reported studies, ongoing investigational efforts, and possibilities for future studies in advanced hepatocellular carcinoma. PMID:29151326

Proliferation: Threat and Response

DTIC Science & Technology

1997-11-01

primary agent, the Defense Technology capabilities also contribute to ongoing efforts to Security Administration ( DTSA ). These efforts are focus and...Special Weapons Agency Organization DTSA Defense Technology Security BW Biological Weapons Administration BWC Biological and Toxin Weapons EPCI Enhanced

Measure once, cut twice--adding patient-reported outcome measures to the electronic health record for comparative effectiveness research.

PubMed

Wu, Albert W; Kharrazi, Hadi; Boulware, L Ebony; Snyder, Claire F

2013-08-01

This article presents the current state of patient-reported outcome measures and explains new opportunities for leveraging the recent adoption of electronic health records to expand the application of patient-reported outcomes in both clinical care and comparative effectiveness research. Historic developments of patient-reported outcome, electronic health record, and comparative effectiveness research are analyzed in two dimensions: patient centeredness and digitization. We pose the question, "What needs to be standardized around the collection of patient-reported outcomes in electronic health records for comparative effectiveness research?" We identified three converging trends: the progression of patient-reported outcomes toward greater patient centeredness and electronic adaptation; the evolution of electronic health records into personalized and fully digitized solutions; and the shift toward patient-oriented comparative effectiveness research. Related to this convergence, we propose an architecture for patient-reported outcome standardization that could serve as a first step toward a more comprehensive integration of patient-reported outcomes with electronic health record for both practice and research. The science of patient-reported outcome measurement has matured sufficiently to be integrated routinely into electronic health records and other electronic health solutions to collect data on an ongoing basis for clinical care and comparative effectiveness research. Further efforts and ideally coordinated efforts from various stakeholders are needed to refine the details of the proposed framework for standardization. Copyright © 2013 Elsevier Inc. All rights reserved.

Alternative Fuel for Marine Application

DOT National Transportation Integrated Search

2012-02-29

The U.S. Maritime Administration (MARAD) is participating in the U.S. Navy's ongoing efforts to test alternative fuels for marine use by demonstrating their applicability on commercial vessels. In support of this effort, the Navy provided neat hydrot...

Stormtime Magnetosphere-Ionosphere-Thermosphere Interactions and Dynamics

DTIC Science & Technology

2013-03-13

1 2. BACKGROUND ... BACKGROUND The studies described in this report were performed in support of ongoing and planned space weather programs in the areas of Space Situational...Ionosphere The purpose of this effort was to initiate on-going analysis of COSMIC -GPS measurements of total electron content (TEC) in the dayside

Exposure Modeling Tools and Databases for Consideration for Relevance to the Amended TSCA (ISES)

EPA Science Inventory

The Agency’s Office of Research and Development (ORD) has a number of ongoing exposure modeling tools and databases. These efforts are anticipated to be useful in supporting ongoing implementation of the amended Toxic Substances Control Act (TSCA). Under ORD’s Chemic...

Leaving No Stone Unturned in the Pursuit of New Physics

DOE Office of Scientific and Technical Information (OSTI.GOV)

Cohen, Timothy

The major goal of this project was to investigate a variety of topics in theoretical particle physics, with an emphasis on beyond the Standard Model phenomena. A particular emphasis is placed on making a connection to ongoing experimental efforts designed to extend our knowledge of the fundamental physics frontiers. The principal investigator aimed to play a leading role in theoretical research that complements this impressive experimental endeavor. Progress requires a strong synergy between the theoretical and experimental communities to design and interpret the data that is produced. Thus, this project's main goal was to improve our understanding of models, signatures,more » and techniques as we continue the hunt for new physics.« less

Therapeutic Inertia and Treatment Intensification.

PubMed

Josiah Willock, Robina; Miller, Joseph B; Mohyi, Michelle; Abuzaanona, Ahmed; Muminovic, Meri; Levy, Phillip D

2018-01-29

This review aims to emphasize how therapeutic inertia, the failure of clinicians to intensify treatment when blood pressure rises or remains above therapeutic goals, contributes to suboptimal blood pressure control in hypertensive populations. Studies reveal that the therapeutic inertia is quite common and contributes to suboptimal blood pressure control. Quality improvement programs and standardized approaches to support antihypertensive treatment intensification are ways to combat therapeutic inertia. Furthermore, programs that utilize non-physician medical professionals such as pharmacists and nurses demonstrate promise in mitigating the effects of this important problem. Therapeutic inertia impedes antihypertensive management and requires a broad effort to reduce its effects. There is an ongoing need for renewed focus and research in this area to improve hypertension control.

PDA Single-Use Systems Cross-Organizational Workshop-Meeting Summary, May 14, 2014-PDA Global Headquarters, Bethesda, MD.

PubMed

Repetto, Robert; Levy, Richard

2015-01-01

The application of single-use systems, or disposables, has increased dramatically in the past 10 years. Although some elements of the pharmaceutical and biotech manufacturing process were single-use and therefore disposable and not reused, the majority of the process equipment and fluid path was cleaned and reused by end users. Today, much more of the manufacturing process is composed of single-use systems, and there are some biotech plants that use single-use systems exclusively. Because of this increasing reliance on suppliers, there is an urgent need for more formal standards specifically for single-use system technology. The objective of this PDA-sponsored workshop held on May 14, 2014 was twofold: (1) to promote a harmonized approach to supporting single-use system activities within the industry and in so doing to minimize duplication of efforts, and (2) to communicate ongoing single-use system initiatives among the group. Representatives of ASME, ASTM, BPOG, BPSA, ELSIE, PDA, PQRI, and USP, as well as representatives of CBER and CDER of FDA, attended. Today, the majority of pharmaceutical and biotech drug manufacturing equipment is cleaned and reused. However, in the past 10 years, the use of disposable manufacturing systems has increased dramatically; there are even some biotech-derived drugs that are manufactured entirely using single-use technology. This movement toward disposables has placed increased reliance on disposable equipment suppliers, each of which manufactures its products independently to meet customer needs. This fact has led to non-uniformity in design for connectors and similar sub-processes, and has made the need for more formal industry standards. The objective of this PDA-sponsored workshop held on May 14, 2014 was twofold: (1) to promote a harmonized approach to supporting single-use system projects within the industry and in so doing to minimize duplication of efforts, and (2) to communicate ongoing single-use system initiatives among the group. Representatives of industry associations and standard-setting organizations, as well as representatives of the U.S. Food and Drug Administration, attended. © PDA, Inc. 2015.

Near-Source Modeling Updates: Building Downwash & Near-Road

EPA Science Inventory

The presentation describes recent research efforts in near-source model development focusing on building downwash and near-road barriers. The building downwash section summarizes a recent wind tunnel study, ongoing computational fluid dynamics simulations and efforts to improve ...

IDENTIFICATION OF CFC AND HCFC SUBSTITUTES FOR BLOWING POLYURETHANE FOAM INSULATION PRODUCTS

EPA Science Inventory

The report gives results of a cooperative effort to identiry chlorofluorocarbons and hydrochlorofluorocarbon substitutes for blowing polyurethane foam insulation products. The substantial ongoing effort is identifying third-generation blowing agets for polyurethane foams to repla...

Proteomics Standards Initiative: Fifteen Years of Progress and Future Work

PubMed Central

2017-01-01

The Proteomics Standards Initiative (PSI) of the Human Proteome Organization (HUPO) has now been developing and promoting open community standards and software tools in the field of proteomics for 15 years. Under the guidance of the chair, cochairs, and other leadership positions, the PSI working groups are tasked with the development and maintenance of community standards via special workshops and ongoing work. Among the existing ratified standards, the PSI working groups continue to update PSI-MI XML, MITAB, mzML, mzIdentML, mzQuantML, mzTab, and the MIAPE (Minimum Information About a Proteomics Experiment) guidelines with the advance of new technologies and techniques. Furthermore, new standards are currently either in the final stages of completion (proBed and proBAM for proteogenomics results as well as PEFF) or in early stages of design (a spectral library standard format, a universal spectrum identifier, the qcML quality control format, and the Protein Expression Interface (PROXI) web services Application Programming Interface). In this work we review the current status of all of these aspects of the PSI, describe synergies with other efforts such as the ProteomeXchange Consortium, the Human Proteome Project, and the metabolomics community, and provide a look at future directions of the PSI. PMID:28849660

Proteomics Standards Initiative: Fifteen Years of Progress and Future Work.

PubMed

Deutsch, Eric W; Orchard, Sandra; Binz, Pierre-Alain; Bittremieux, Wout; Eisenacher, Martin; Hermjakob, Henning; Kawano, Shin; Lam, Henry; Mayer, Gerhard; Menschaert, Gerben; Perez-Riverol, Yasset; Salek, Reza M; Tabb, David L; Tenzer, Stefan; Vizcaíno, Juan Antonio; Walzer, Mathias; Jones, Andrew R

2017-12-01

The Proteomics Standards Initiative (PSI) of the Human Proteome Organization (HUPO) has now been developing and promoting open community standards and software tools in the field of proteomics for 15 years. Under the guidance of the chair, cochairs, and other leadership positions, the PSI working groups are tasked with the development and maintenance of community standards via special workshops and ongoing work. Among the existing ratified standards, the PSI working groups continue to update PSI-MI XML, MITAB, mzML, mzIdentML, mzQuantML, mzTab, and the MIAPE (Minimum Information About a Proteomics Experiment) guidelines with the advance of new technologies and techniques. Furthermore, new standards are currently either in the final stages of completion (proBed and proBAM for proteogenomics results as well as PEFF) or in early stages of design (a spectral library standard format, a universal spectrum identifier, the qcML quality control format, and the Protein Expression Interface (PROXI) web services Application Programming Interface). In this work we review the current status of all of these aspects of the PSI, describe synergies with other efforts such as the ProteomeXchange Consortium, the Human Proteome Project, and the metabolomics community, and provide a look at future directions of the PSI.

Model-Based Engineering Design for Trade Space Exploration throughout the Design Cycle

NASA Technical Reports Server (NTRS)

Lamassoure, Elisabeth S.; Wall, Stephen D.; Easter, Robert W.

2004-01-01

This paper presents ongoing work to standardize model-based system engineering as a complement to point design development in the conceptual design phase of deep space missions. It summarizes two first steps towards practical application of this capability within the framework of concurrent engineering design teams and their customers. The first step is standard generation of system sensitivities models as the output of concurrent engineering design sessions, representing the local trade space around a point design. A review of the chosen model development process, and the results of three case study examples, demonstrate that a simple update to the concurrent engineering design process can easily capture sensitivities to key requirements. It can serve as a valuable tool to analyze design drivers and uncover breakpoints in the design. The second step is development of rough-order- of-magnitude, broad-range-of-validity design models for rapid exploration of the trade space, before selection of a point design. At least one case study demonstrated the feasibility to generate such models in a concurrent engineering session. The experiment indicated that such a capability could yield valid system-level conclusions for a trade space composed of understood elements. Ongoing efforts are assessing the practicality of developing end-to-end system-level design models for use before even convening the first concurrent engineering session, starting with modeling an end-to-end Mars architecture.

Upper airway resistance syndrome. Central electroencephalographic power and changes in breathing effort.

PubMed

Black, J E; Guilleminault, C; Colrain, I M; Carrillo, O

2000-08-01

Upper airway resistance syndrome (UARS) is defined by excessive daytime sleepiness and tiredness, and is associated with increased breathing effort. Its polygraphic features involve progressive increases in esophageal pressure (Pes), terminated by arousal (AR) as defined by the American Sleep Disorders Association (ASDA). With the arousal there is an abrupt decrease in Pes, called Pes reversal. However, Pes reversal can be seen without the presence of an AR. We performed spectral analysis on electroencephalographic data from a central lead for both AR and nonarousal (N-AR) events obtained from 15 UARS patients (eight men and seven women). Delta band activity was increased before and surrounding Pes reversal regardless of the presence or absence of AR. In the period after Pes reversal, alpha, sigma, and beta activity showed a greater increase in AR events than in N-AR events. The Pes measures were identical leading up to the point of reversal, but showed a longer-lasting and significantly greater decrease in respiratory effort after an AR. The data indicate that substantial electroencephalographic changes can be identified in association with Pes events, even when ARs cannot be detected according to standard criteria; however, visually identifiable electroencephalographic arousals clearly have a greater impact on ongoing inspiratory effort.

Cachexia: common, deadly, with an urgent need for precise definition and new therapies.

PubMed

Lainscak, Mitja; Filippatos, Gerasimos S; Gheorghiade, Mihai; Fonarow, Gregg C; Anker, Stefan D

2008-06-02

Cachexia--sometimes also referred to as wasting disease, malnutrition, or hypercatabolism--has been described for centuries and has always raised ominous thoughts that "the end is near." The disease is encountered in many malignant and nonmalignant chronic, ultimately fatal, illnesses. Yet, although cachexia is a deadly syndrome, little is known about its pathophysiology, and the debate regarding its definition is ongoing. Thus, the data on epidemiology can be contested, but a few things are certain: Cachexia is associated with exceedingly high mortality once the syndrome has fully developed, irrespective of the definition we apply, and it is associated with weakness, weight loss, muscle wasting, and inflammation. It is not simply an ancillary event, and it may contribute to the death of the patient either through effects on neuroendocrine and immune defense mechanisms or through protein calorie malnutrition. The therapeutic standard of care for cachexia remains undefined to date, with a few exceptions. Among the recognized approaches, exogenous oral amino acid supplementation appears very promising. Further research efforts are needed and they are ongoing.

Survey of self-assessed preparedness for clinical practice in one Croatian medical school

PubMed Central

Bojanić, Katarina; Schears, Gregory J; Schroeder, Darrell R; Jenkins, Sarah M; Warner, David O; Sprung, Juraj

2009-01-01

Background The Croatian higher education system is in the process of reforming its medical curricula to comply with European Union standards. We conducted a survey of students enrolled at the University of Zagreb (Croatia) asking them to rate their perception of preparedness for clinical practice prior to initiation of the reform process. The purpose of the survey was to identify self-perceived deficiencies in education and to establish a reference point for the later assessment of ongoing educational reform. Findings One-hundred and forty seven (N = 147) graduates reported the levels of perceived preparedness on 30 items grouped into 8 educational domains. Main domains were: understanding science, practical skills/patient management, holistic care, prevention, interpersonal skills, confidence/coping skills, collaboration, and self-directed learning. For each item, graduates self assessed their preparedness on a scale ranging from 1 to 4, with 1 = "Very inadequate", 2 = "Somewhat inadequate", 3 = "Somewhat adequate", and 4 = "Very adequate". In 7 out of 8 domains the achieved median score was ≥ 3. Students expressed low confidence (defined when ≥ 25% of respondents supplied a rating for the survey question as: "very inadequate" or "somewhat inadequate") with interpersonal skills (discussing terminal disease, counseling distraught patients, balancing professional and personal life), and in performing certain basic semi-invasive or invasive procedures. Conclusion Zagreb medical graduates identified several deficiencies within educational domains required for standard clinical practice. Ongoing educational efforts need to be directed towards the correction of these deficiencies in order to achieve standards required by the European Union. PMID:19635136

Repositioning Science Reform Efforts: Four Practical Recommendations from the Field

ERIC Educational Resources Information Center

Ness, Daniel; Farenga, Stephen J.; Shah, Vishal; Garofalo, Salvatore G.

2016-01-01

Appeals to reform science education by policy makers are not new phenomena. To be sure, while science reform efforts have been ongoing occurrences for nearly six decades, perpetual educational reform efforts as a whole have been evolving and gaining momentum in number for more than a century. The general motivation for continual reform appears to…

40 CFR Appendix W to Part 51 - Guideline on Air Quality Models

Code of Federal Regulations, 2013 CFR

2013-07-01

... in the Guideline. The third activity is the extensive on-going research efforts by EPA and others in... addition, findings from ongoing research programs, new model development, or results from model evaluations... shown that the model is not biased toward underestimates; and v. A protocol on methods and procedures to...

40 CFR Appendix W to Part 51 - Guideline on Air Quality Models

Code of Federal Regulations, 2012 CFR

2012-07-01

... in the Guideline. The third activity is the extensive on-going research efforts by EPA and others in... addition, findings from ongoing research programs, new model development, or results from model evaluations... shown that the model is not biased toward underestimates; and v. A protocol on methods and procedures to...

40 CFR Appendix W to Part 51 - Guideline on Air Quality Models

Code of Federal Regulations, 2014 CFR

2014-07-01

... in the Guideline. The third activity is the extensive on-going research efforts by EPA and others in... addition, findings from ongoing research programs, new model development, or results from model evaluations... shown that the model is not biased toward underestimates; and v. A protocol on methods and procedures to...

Development and Preparation of Lead-Containing Paint Films and Diagnostic Test Materials

EPA Science Inventory

Lead in paint continues to be a threat to children’s health in cities across the United States, which means there is an ongoing need for testing and analysis of paint. This ongoing analytical effort and especially development of new methods continue to drive the need for diagnost...

Improving Collaboration by Standardization Efforts in Systems Biology

PubMed Central

Dräger, Andreas; Palsson, Bernhard Ø.

2014-01-01

Collaborative genome-scale reconstruction endeavors of metabolic networks would not be possible without a common, standardized formal representation of these systems. The ability to precisely define biological building blocks together with their dynamic behavior has even been considered a prerequisite for upcoming synthetic biology approaches. Driven by the requirements of such ambitious research goals, standardization itself has become an active field of research on nearly all levels of granularity in biology. In addition to the originally envisaged exchange of computational models and tool interoperability, new standards have been suggested for an unambiguous graphical display of biological phenomena, to annotate, archive, as well as to rank models, and to describe execution and the outcomes of simulation experiments. The spectrum now even covers the interaction of entire neurons in the brain, three-dimensional motions, and the description of pharmacometric studies. Thereby, the mathematical description of systems and approaches for their (repeated) simulation are clearly separated from each other and also from their graphical representation. Minimum information definitions constitute guidelines and common operation protocols in order to ensure reproducibility of findings and a unified knowledge representation. Central database infrastructures have been established that provide the scientific community with persistent links from model annotations to online resources. A rich variety of open-source software tools thrives for all data formats, often supporting a multitude of programing languages. Regular meetings and workshops of developers and users lead to continuous improvement and ongoing development of these standardization efforts. This article gives a brief overview about the current state of the growing number of operation protocols, mark-up languages, graphical descriptions, and fundamental software support with relevance to systems biology. PMID:25538939

The International Reference Ionosphere - Climatological Standard for the Ionosphere

NASA Technical Reports Server (NTRS)

Bilitza, Dieter

2006-01-01

The International Reference Ionosphere (IRI) a joint project of URSI and COSPAR is the defacto standard for a climatological specification of ionospheric parameters. IRI is based on a wide range of ground and space data and has been steadily improved since its inception in 1969 with the ever-increasing volume of ionospheric data and with better mathematical descriptions of the observed global and temporal variation patterns. The IRI model has been validated with a large amount of data including data from the most recent ionospheric satellites (KOMPSAT, ROCSAT and TIMED) and data from global network of ionosondes. Several IRI teams are working on specific aspects of the IRI modeling effort including an improved representation of the topside ionosphere with a seamless transition to the plasmasphere, a new effort to represent the global variation of F2 peak parameters using the Neural Network (NN) technique, and the inclusion of several additional parameters in IRI, e.g., spread-F probability and ionospheric variability. Annual IRI workshops are the forum for discussions of these efforts and for all science activities related to IRI as well as applications of the IRI model in engineering and education. In this paper I will present a status report about the IRI effort with special emphasis on the presentations and results from the most recent IRI Workshops (Paris, 2004; Tortosa, 2005) and on the most important ongoing IRI activities. I will discuss the latest version of the IRI model, IRI-2006, highlighting the most recent changes and additions. Finally, the talk will review some of the applications of the IRI model with special emphasis on the use for radiowave propagation studies and communication purposes.

Procedures and Concepts of EPA's Ongoing Sensor Evaluation Efforts

EPA Science Inventory

The purpose of this research effort was to develop an understanding of what technology might prove valuable in conducting the next generation of air monitoring. Upon their discovery, such technologies were obtained in collaboration with inventors and commercial and research orga...

Washington State's model of physician leadership in cardiac outcomes reporting.

PubMed

Goss, J R; Whitten, R W; Phillips, R C; Johnston, G G; Hofer, B O; Mansfield, P B; Tidwell, S L; Spertus, J A; LoGerfo, J P

2000-09-01

In 1993, the cardiac surgery community in Washington State opposed an effort by the state Health Care Authority (HCA) to identify "centers of excellence" for selective contracting of coronary artery bypass grafting (CABG) procedures, and proposed an alternate model that would create a statewide cardiac outcomes registry under physician governance to be used by all institutions for internal quality improvement activities. A prospective pilot data collection effort, which examined preoperative and postoperative patient-reported health status, served as the basis for evaluating the capacity of a physician-led organization to develop a collaborative atmosphere and facilitate universal hospital participation. A surgical steering group met on a regular basis and reached consensus on governance issues, protocols for standardized data collection, and policies regarding data dissemination. All 14 centers that performed bypass surgery in the state participated. Patients who were surveyed reported statistically significant improvements in physical, emotional, and anginal-specific health status after bypass surgery. Baseline patient characteristics and longitudinal outcomes were compared across institutions. Based on the feasibility of this collaborative outcomes reporting program, the HCA revised its policy regarding selective contracting and has helped to support an ongoing physician-led and -governed cardiac outcomes reporting system that is particularly notable for the subsequent integration of both CABG surgery and catheterization-based procedures into one standardized registry.

Unmanned Aircraft Systems (UAS) Integration in the National Airspace System (NAS) Project

NASA Technical Reports Server (NTRS)

Shively, Jay

2017-01-01

Over the past 5 years, the UAS integration into the NAS project has worked to reduce technical barriers to integration. A major focus of this work has been in support of RTCA SC-228. This committee has recently published the first UAS integration minimum performance standards (MOPS). This work has spanned detect and avoid (DAA) as well as command and control comm datalinks. I will discuss DAA efforts with focus on the human systems work. I will discuss how automation was discussed and addressed within this context. ICAO stood up a remotely piloted aircraft systems (RPAS) panel in 2014. They have developed an RPAS manual and are now working to revise existing annexes and standards and recommended practices. The Human In The System (HITS) has worked to infuse human factors guidelines into those documents. I will discuss that effort as well as how ICAO has defined and address autonomy. There is a great deal of interest in the control of multiple vehicles by a single operator. The UAS EXCOM Science and Research Panel (SARP) is holding a workshop on this topic in late June. I will discuss research performed on this topic when I worked for the Army and on-going work within the division and a NATO working group on Human-Autonomy Teaming.

Compensation for occupational neurological and mental disorders.

PubMed

Kang, Dong-Mug; Kim, Inah

2014-06-01

Standards for the recognition of occupational diseases (ODs) in Korea were established in 1954 and have been amended several times. In 2013, there was a significant change in these standards. On the basis of scientific evidence and causality, the International Labour Organization list, European Commission schedule, and compensated cases in Korea were reviewed to revise the previous standards for the recognition of ODs in Korea. A disease-based approach using the International Classification of Diseases (10th version) was added on the previous standards, which were agent-specific approaches. The amended compensable occupational neurological disorders and occupational mental disorders (OMDs) in Korea are acute and chronic central nervous system (CNS) disorders, toxic neuropathy, peripheral neuropathy, manganese-related disorders, and post-traumatic stress disorder. Several agents including trichloroethylene (TCE), benzene, vinyl chloride, organotin, methyl bromide, and carbon monoxide (CO) were newly included as acute CNS disorders. TCE, lead, and mercury were newly included as chronic CNS disorders. Mercury, TCE, methyl n-butyl ketone, acrylamide, and arsenic were newly included in peripheral neuropathy. Post-traumatic stress disorders were newly included as the first OMD. This amendment makes the standard more comprehensive and practical. However, this amendment does not perfectly reflect the recent scientific progress and social concerns. Ongoing effort, research, and expert consensus are needed to improve the standard.

Introducing criteria based audit into Ugandan maternity units.

PubMed

Weeks, A D; Alia, G; Ononge, S; Mutungi, A; Otolorin, E O; Mirembe, F M

2004-02-01

Maternal mortality in Uganda has remained unchanged at 500/100 000 over the past 10 years despite concerted efforts to improve the standard of maternity care. It is especially difficult to improve standards in rural areas, where there is little money for improvements. Furthermore, staff may be isolated, poorly paid, disempowered, lacking in morale, and have few skills to bring about change. Training programme to introduce criteria based audit into rural Uganda. Makerere University Medical School, Mulago Hospital (large government teaching hospital in Kampala), and Mpigi District (rural area with 10 small health centres around a district hospital). Didactic teaching about criteria based audit followed by practical work in own units, with ongoing support and follow up workshops. Improvements were seen in many standards of care. Staff showed universal enthusiasm for the training; many staff produced simple, cost-free improvements in their standard of care. Teaching of criteria based audit to those providing health care in developing countries can produce low cost improvements in the standards of care. Because the method is simple and can be used to provide improvements even without new funding, it has the potential to produce sustainable and cost effective changes in the standard of health care. Follow up is needed to prevent a waning of enthusiasm with time.

A simple web-based tool to compare freshwater fish data collected using AFS standard methods

USGS Publications Warehouse

Bonar, Scott A.; Mercado-Silva, Norman; Rahr, Matt; Torrey, Yuta T.; Cate, Averill

2016-01-01

The American Fisheries Society (AFS) recently published Standard Methods for Sampling North American Freshwater Fishes. Enlisting the expertise of 284 scientists from 107 organizations throughout Canada, Mexico, and the United States, this text was developed to facilitate comparisons of fish data across regions or time. Here we describe a user-friendly web tool that automates among-sample comparisons in individual fish condition, population length-frequency distributions, and catch per unit effort (CPUE) data collected using AFS standard methods. Currently, the web tool (1) provides instantaneous summaries of almost 4,000 data sets of condition, length frequency, and CPUE of common freshwater fishes collected using standard gears in 43 states and provinces; (2) is easily appended with new standardized field data to update subsequent queries and summaries; (3) compares fish data from a particular water body with continent, ecoregion, and state data summaries; and (4) provides additional information about AFS standard fish sampling including benefits, ongoing validation studies, and opportunities to comment on specific methods. The web tool—programmed in a PHP-based Drupal framework—was supported by several AFS Sections, agencies, and universities and is freely available from the AFS website and fisheriesstandardsampling.org. With widespread use, the online tool could become an important resource for fisheries biologists.

Ongoing Fixed Wing Research within the NASA Langley Aeroelasticity Branch

NASA Technical Reports Server (NTRS)

Bartels, Robert; Chwalowski, Pawel; Funk, Christie; Heeg, Jennifer; Hur, Jiyoung; Sanetrik, Mark; Scott, Robert; Silva, Walter; Stanford, Bret; Wiseman, Carol

2015-01-01

The NASA Langley Aeroelasticity Branch is involved in a number of research programs related to fixed wing aeroelasticity and aeroservoelasticity. These ongoing efforts are summarized here, and include aeroelastic tailoring of subsonic transport wing structures, experimental and numerical assessment of truss-braced wing flutter and limit cycle oscillations, and numerical modeling of high speed civil transport configurations. Efforts devoted to verification, validation, and uncertainty quantification of aeroelastic physics in a workshop setting are also discussed. The feasibility of certain future civil transport configurations will depend on the ability to understand and control complex aeroelastic phenomena, a goal that the Aeroelasticity Branch is well-positioned to contribute through these programs.

Measure Once, Cut Twice – Adding Patient-Reported Outcome Measures to the Electronic Health Record for Comparative Effectiveness Research

PubMed Central

Wu, Albert W.; Kharrazi, Hadi; Boulware, L. Ebony; Snyder, Claire F.

2013-01-01

Objective This paper presents the current state of patient-reported outcome measures, and explains new opportunities for leveraging the recent adoption of electronic health records to expand the application of patient-reported outcomes in both clinical care and comparative effectiveness research. Study Design and Setting Historic developments of patient-reported outcome, electronic health record, and comparative effectiveness research are analyzed in two dimensions: patient-centeredness and digitization. We pose the question: “What needs to be standardized around the collection of patient-reported outcomes in electronic health records for comparative effectiveness research?” Results We identified three converging trends: the progression of patient-reported outcomes toward greater patient centeredness and electronic adaptation; the evolution of electronic health records into personalized and fully digitized solutions; the shift toward patient-oriented comparative effectiveness research. Related to this convergence, we propose an architecture for patient-reported outcome standardization that could serve as a first step toward a more comprehensive integration of patient-reported outcomes with electronic health record for both practice and research. Conclusion The science of patient-reported outcome measurement has matured sufficiently to be integrated routinely into electronic health records and other e-health solutions to collect data on an ongoing basis for clinical care and comparative effectiveness research. Further efforts and ideally coordinated efforts from various stakeholders are needed to refine the details of the proposed framework for standardization. PMID:23849145

Process Improvement in a Radically Changing Organization

NASA Technical Reports Server (NTRS)

Varga, Denise M.; Wilson, Barbara M.

2007-01-01

This presentation describes how the NASA Glenn Research Center planned and implemented a process improvement effort in response to a radically changing environment. As a result of a presidential decision to redefine the Agency's mission, many ongoing projects were canceled and future workload would be awarded based on relevance to the Exploration Initiative. NASA imposed a new Procedural Requirements standard on all future software development, and the Center needed to redesign its processes from CMM Level 2 objectives to meet the new standard and position itself for CMMI. The intended audience for this presentation is systems/software developers and managers in a large, research-oriented organization that may need to respond to imposed standards while also pursuing CMMI Maturity Level goals. A set of internally developed tools will be presented, including an overall Process Improvement Action Item database, a formal inspection/peer review tool, metrics collection spreadsheet, and other related technologies. The Center also found a need to charter Technical Working Groups (TWGs) to address particular Process Areas. In addition, a Marketing TWG was needed to communicate the process changes to the development community, including an innovative web site portal.

Standardization in laboratory medicine: Adoption of common reference intervals to the Croatian population.

PubMed

Flegar-Meštrić, Zlata; Perkov, Sonja; Radeljak, Andrea

2016-03-26

Considering the fact that the results of laboratory tests provide useful information about the state of health of patients, determination of reference value is considered an intrinsic part in the development of laboratory medicine. There are still huge differences in the analytical methods used as well as in the associated reference intervals which could consequently significantly affect the proper assessment of patient health. In a constant effort to increase the quality of patients' care, there are numerous international initiatives for standardization and/or harmonization of laboratory diagnostics in order to achieve maximum comparability of laboratory test results and improve patient safety. Through the standardization and harmonization processes of analytical methods the ability to create unique reference intervals is achieved. Such reference intervals could be applied globally in all laboratories using methods traceable to the same reference measuring system and analysing the biological samples from the populations with similar socio-demographic and ethnic characteristics. In this review we outlined the results of the harmonization processes in Croatia in the field of population based reference intervals for clinically relevant blood and serum constituents which are in accordance with ongoing activity for worldwide standardization and harmonization based on traceability in laboratory medicine.

The Bnl Muon Anomalous Magnetic Moment Measurement

NASA Astrophysics Data System (ADS)

Hertzog, David W.

2003-09-01

The E821 experiment at Brookhaven National Laboratory is designed to measure the muon magnetic anomaly, aμ, to an ultimate precision of 0.4 parts per million (ppm). Because theory can predict aμ to 0.6 ppm, and ongoing efforts aim to reduce this uncertainty, the comparison represents an important and sensitive test of new physics. At the time of this Workshop, the reported experimental result from the 1999 running period achieved aμ+ = 11 659 202(14)(6) x 10-10 (1.3 ppm) and differed from the most precise theory evaluation by 2.6 standard deviations. Considerable additional data has already been obtained in 2000 and 2001 and the analysis of this data is proceeding well. Intense theoretical activity has also taken place ranging from suggestions of the new physics which could account for the deviation to careful re-examination of the standard model contributions themselves. Recently, a re-evaluation of the pion pole contribution to the hadronic light-by-light process exposed a sign error in earlier studies used in the standard theory. With this correction incorporated, experiment and theory disagree by a modest 1.6 standard deviations.

Standardization in laboratory medicine: Adoption of common reference intervals to the Croatian population

PubMed Central

Flegar-Meštrić, Zlata; Perkov, Sonja; Radeljak, Andrea

2016-01-01

Considering the fact that the results of laboratory tests provide useful information about the state of health of patients, determination of reference value is considered an intrinsic part in the development of laboratory medicine. There are still huge differences in the analytical methods used as well as in the associated reference intervals which could consequently significantly affect the proper assessment of patient health. In a constant effort to increase the quality of patients’ care, there are numerous international initiatives for standardization and/or harmonization of laboratory diagnostics in order to achieve maximum comparability of laboratory test results and improve patient safety. Through the standardization and harmonization processes of analytical methods the ability to create unique reference intervals is achieved. Such reference intervals could be applied globally in all laboratories using methods traceable to the same reference measuring system and analysing the biological samples from the populations with similar socio-demographic and ethnic characteristics. In this review we outlined the results of the harmonization processes in Croatia in the field of population based reference intervals for clinically relevant blood and serum constituents which are in accordance with ongoing activity for worldwide standardization and harmonization based on traceability in laboratory medicine. PMID:27019800

Application of ISO standard 27048: dose assessment for the monitoring of workers for internal radiation exposure.

PubMed

Henrichs, K

2011-03-01

Besides ongoing developments in the dosimetry of incorporated radionuclides, there are various efforts to improve the monitoring of workers for potential or real intakes of radionuclides. The disillusioning experience with numerous intercomparison projects identified substantial differences between national regulations, concepts, applied programmes and methods, and dose assessment procedures. Measured activities were not directly comparable because of significant differences between measuring frequencies and methods, but also results of case studies for dose assessments revealed differences of orders of magnitude. Besides the general common interest in reliable monitoring results, at least the cross-border activities of workers (e.g. nuclear power plant services) require consistent approaches and comparable results. The International Standardization Organization therefore initiated projects to standardise programmes for the monitoring of workers, the requirements for measuring laboratories and the processes for the quantitative evaluation of monitoring results in terms of internal assessed doses. The strength of the concepts applied by the international working group consists in a unified approach defining the requirements, databases and processes. This paper is intended to give a short introduction into the standardization project followed by a more detailed description of the dose assessment standard, which will be published in the very near future.

Efforts to Bridge the Gap between Research and Practice in Social Work: Precedents and Prospects: Keynote Address at the Bridging the Gap Symposium

ERIC Educational Resources Information Center

Rubin, Allen

2015-01-01

This keynote address discusses previous and ongoing efforts to reduce the persistent gap between research and practice in social work and offers recommendations for further bridging that gap. Key among those recommendations is the need to conduct descriptive outcome studies of efforts to adapt research-supported interventions in everyday practice…

NASA and The Semantic Web

NASA Technical Reports Server (NTRS)

Ashish, Naveen

2005-01-01

We provide an overview of several ongoing NASA endeavors based on concepts, systems, and technology from the Semantic Web arena. Indeed NASA has been one of the early adopters of Semantic Web Technology and we describe ongoing and completed R&D efforts for several applications ranging from collaborative systems to airspace information management to enterprise search to scientific information gathering and discovery systems at NASA.

Factors in Sustaining Professional Learning Community

ERIC Educational Resources Information Center

Kilbane, James F., Jr.

2009-01-01

School change efforts to develop schools as learning communities result in schools that are constantly learning and thus changing. This collective case study of four schools involved in a 4-year reform effort begins to examine the ongoing sustainability of a learning community. The study draws insights about the sustainability of learning…

DOE Office of Scientific and Technical Information (OSTI.GOV)

Brunett, A. J.; Fanning, T. H.

The United States has extensive experience with the design, construction, and operation of sodium cooled fast reactors (SFRs) over the last six decades. Despite the closure of various facilities, the U.S. continues to dedicate research and development (R&D) efforts to the design of innovative experimental, prototype, and commercial facilities. Accordingly, in support of the rich operating history and ongoing design efforts, the U.S. has been developing and maintaining a series of tools with capabilities that envelope all facets of SFR design and safety analyses. This paper provides an overview of the current U.S. SFR analysis toolset, including codes such asmore » SAS4A/SASSYS-1, MC2-3, SE2-ANL, PERSENT, NUBOW-3D, and LIFE-METAL, as well as the higher-fidelity tools (e.g. PROTEUS) being integrated into the toolset. Current capabilities of the codes are described and key ongoing development efforts are highlighted for some codes.« less

The road to pharmacist prescribing in Alberta Health Services.

PubMed

Gray, Margaret; Mysak, Tania

2016-09-15

The implementation of policy within a health organization to support a new legislative and regulatory framework of pharmacist prescribing in the Canadian province of Alberta is described. The evolution of pharmacists' practice activities to encompass medication management through independent prescribing authority has occurred in many jurisdictions around the world. In 2007, Alberta pharmacists were granted the most progressive scope of practice in all of North America. Pursuant to a series of legislative and regulatory initiatives enacted since 2000, the provincial health authority, Alberta Health Services (AHS), has worked to (1) establish a policy framework that supports pharmacist prescribing, (2) provide opportunities for pharmacist prescribing in both inpatient and ambulatory care practice environments, and (3) provide motivation and resources for AHS pharmacists to acquire "additional prescribing authorization" (APA) that enables them to independently prescribe and manage patients' ongoing drug therapy. Pharmacists with APA currently are permitted to prescribe all medications requiring a prescription, with the exception of opiates and other controlled substances; efforts to expand pharmacist prescribing to include those medications are ongoing. Currently, nearly half of all AHS pharmacists have APA. The health authority plans to make APA a standard expectation for all clinical pharmacists working in collaborative practice settings. Opportunities provided to Alberta pharmacists by legislation have been embraced by the provincial health authority. The AHS leadership remains committed to ensuring that its pharmacists practice to the full extent of their scope of practice and actively encourages and supports them in their efforts to provide optimal patient care. Copyright © 2016 by the American Society of Health-System Pharmacists, Inc. All rights reserved.

Time to finger point or fix? An invitation to join ongoing efforts to promote ethical authorship and other good publication practices.

PubMed

Woolley, Karen L; Gertel, Art; Hamilton, Cindy W; Jacobs, Adam; Snyder, Gene P

2013-01-01

In this commentary, we present evidence that unethical authorship (eg, guest and ghost authoring) and other publication practices are not restricted to the pharmaceutical industry; they also occur in academia. Such practices are not an industry problem--they are a research problem. To enhance trust in industry-sponsored research, companies have made rapid and far-reaching changes to their publication guidelines, policies, and procedures. Professional medical writers have adopted, and continue to implement, these changes. Although evidence indicates that industry practices are improving, there is certainly more to do, both in industry and academia. We invite readers to join ongoing efforts to promote ethical publication practices.

Going Beyond QCD in Lattice Gauge Theory

NASA Astrophysics Data System (ADS)

Fleming, G. T.

2011-01-01

Strongly coupled gauge theories (SCGT's) have been studied theoretically for many decades using numerous techniques. The obvious motivation for these efforts stemmed from a desire to understand the source of the strong nuclear force: Quantum Chromo-dynamics (QCD). Guided by experimental results, theorists generally consider QCD to be a well-understood SCGT. Unfortunately, it is not clear how to extend the lessons learned from QCD to other SCGT's. Particularly urgent motivators for new studies of other SCGT's are the ongoing searches for physics beyond the standard model (BSM) at the Large Hadron Collider (LHC) and the Tevatron. Lattice gauge theory (LGT) is a technique for systematically-improvable calculations in many SCGT's. It has become the standard for non-perturbative calculations in QCD and it is widely believed that it may be useful for study of other SCGT's in the realm of BSM physics. We will discuss the prospects and potential pitfalls for these LGT studies, focusing primarily on the flavor dependence of SU(3) gauge theory.

Usability and accessibility in consumer health informatics current trends and future challenges.

PubMed

Goldberg, Larry; Lide, Bettijoyce; Lowry, Svetlana; Massett, Holly A; O'Connell, Trisha; Preece, Jennifer; Quesenbery, Whitney; Shneiderman, Ben

2011-05-01

It is a truism that, for innovative eHealth systems to have true value and impact, they must first and foremost be usable and accessible by clinicians, consumers, and other stakeholders. In this paper, current trends and future challenges in the usability and accessibility of consumer health informatics will be described. Consumer expectations of their healthcare providers and healthcare records in this new era of consumer-directed care will be explored, and innovative visualizations, assistive technologies, and other ways that healthcare information is currently being provided and/or shared will be described. Challenges for ensuring the usability of current and future systems will also be discussed. An innovative model for conducting systematic, timely, user-centered research on consumer-facing websites at the National Cancer Institute (NCI) and the ongoing efforts at the National Institute of Standards and Technology (NIST) to promote health information technology (HIT) usability standards and evaluation criteria will also be presented. Copyright © 2011 American Journal of Preventive Medicine. All rights reserved.

A Formal Model of Partitioning for Integrated Modular Avionics

NASA Technical Reports Server (NTRS)

DiVito, Ben L.

1998-01-01

The aviation industry is gradually moving toward the use of integrated modular avionics (IMA) for civilian transport aircraft. An important concern for IMA is ensuring that applications are safely partitioned so they cannot interfere with one another. We have investigated the problem of ensuring safe partitioning and logical non-interference among separate applications running on a shared Avionics Computer Resource (ACR). This research was performed in the context of ongoing standardization efforts, in particular, the work of RTCA committee SC-182, and the recently completed ARINC 653 application executive (APEX) interface standard. We have developed a formal model of partitioning suitable for evaluating the design of an ACR. The model draws from the mathematical modeling techniques developed by the computer security community. This report presents a formulation of partitioning requirements expressed first using conventional mathematical notation, then formalized using the language of SRI'S Prototype Verification System (PVS). The approach is demonstrated on three candidate designs, each an abstraction of features found in real systems.

Creating a Statewide Educational Data System for Accountability and Improvement: A Comprehensive Information and Assessment System for Making Evidence-Based Change at School, District, and Policy Levels

ERIC Educational Resources Information Center

Felner, Robert D.; Bolton, Natalie; Seitsinger, Anne M.; Brand, Stephen; Burns, Amy

2008-01-01

This article reports on one ongoing statewide effort to create a high-quality data reporting and utilization system (i.e., High-Performance Learning Community [HiPlaces] Assessment) to inform educational accountability and improvement efforts system. This effort has undergoing refinement for more than a decade. The article describes the features…

Achieving a Prioritized Research and Technology Development Portfolio for the Dust Management Project

NASA Technical Reports Server (NTRS)

Hyatt, Mark J.; Abel, Phillip; Delaune, Paul; Fishman, Julianna; Kohli, Rajiv

2009-01-01

Mission architectures for human exploration of the lunar surface continue to advance as well as the definitions of capability needs, best practices and engineering design to mitigate the impact of lunar dust on exposed systems. The NASA DMP has been established as the agency focal point for dust characterization, technology, and simulant development. As described in this paper, the DMP has defined a process for selecting and justifying its R&T portfolio. The technology prioritization process, which is based on a ranking system according to weighted criteria, has been successfully applied to the current DMP dust mitigation technology portfolio. Several key findings emerged from this assessment. Within the dust removal and cleaning technologies group, there are critical technical challenges that must be overcome for these technologies to be implemented for lunar applications. For example, an in-situ source of CO2 on the moon is essential to the CO2 shower technology. Also, significant development effort is required to achieve technology readiness level TRL 6 for the electrostatic cleaning system for removal of particles smaller than 50 pm. The baseline materials related technologies require considerable development just to achieve TRL 6. It is also a nontrivial effort to integrate the materials in hardware for lunar application. At present, there are no terrestrial applications that are readily adaptable to lunar surface applications nor are there any obvious leading candidates. The unique requirements of dust sealing systems for lunar applications suggest an extensive development effort will be necessary to mature dust sealing systems to TRL 6 and beyond. As discussed here, several alternate materials and technologies have achieved high levels of maturity for terrestrial applications and warrant due diligence in ongoing assessment of the technology portfolio. The present assessment is the initial step in an ongoing effort to continually evaluate the DMP technology portfolio and external non-NASA relevant technology developments efforts to maintain an optimal investment profile. At the same time, there is an ongoing review of agency-wide dust-related R&T activities. The results of these ongoing assessments will be reported in future publications.

Towards Systematic Benchmarking of Climate Model Performance

NASA Astrophysics Data System (ADS)

Gleckler, P. J.

2014-12-01

The process by which climate models are evaluated has evolved substantially over the past decade, with the Coupled Model Intercomparison Project (CMIP) serving as a centralizing activity for coordinating model experimentation and enabling research. Scientists with a broad spectrum of expertise have contributed to the CMIP model evaluation process, resulting in many hundreds of publications that have served as a key resource for the IPCC process. For several reasons, efforts are now underway to further systematize some aspects of the model evaluation process. First, some model evaluation can now be considered routine and should not require "re-inventing the wheel" or a journal publication simply to update results with newer models. Second, the benefit of CMIP research to model development has not been optimal because the publication of results generally takes several years and is usually not reproducible for benchmarking newer model versions. And third, there are now hundreds of model versions and many thousands of simulations, but there is no community-based mechanism for routinely monitoring model performance changes. An important change in the design of CMIP6 can help address these limitations. CMIP6 will include a small set standardized experiments as an ongoing exercise (CMIP "DECK": ongoing Diagnostic, Evaluation and Characterization of Klima), so that modeling groups can submit them at any time and not be overly constrained by deadlines. In this presentation, efforts to establish routine benchmarking of existing and future CMIP simulations will be described. To date, some benchmarking tools have been made available to all CMIP modeling groups to enable them to readily compare with CMIP5 simulations during the model development process. A natural extension of this effort is to make results from all CMIP simulations widely available, including the results from newer models as soon as the simulations become available for research. Making the results from routine performance tests readily accessible will help advance a more transparent model evaluation process.

Managing employee performance.

PubMed

McConnell, Charles R

2004-01-01

Performance management consists of significantly more than periodic evaluation of performance. It is the art and science of dealing with employees in a manner intended to positively influence their thinking and behavior to achieve a desired level of performance. It is essential for the manager to always model positive behavior concerning performance; what one does or says as a manager always has an influence on others. The kinds of employee behavior most likely encountered relative to performance management efforts stem from resistance to change and lack of complete understanding of what is expected. Employee participation must be elicited whenever possible for performance improvement; as far as the inner working details of a specific job are concerned, there is no one who knows the job better than the person who does it everyday. For each task to be done, an employee needs to know what output is expected, how this output will be measured, and what standards are applied in assessing the output. Managing employee performance requires ongoing contact with each employee, regular feedback, and whatever coaching, counseling, and training are necessary to bring an employee back on track when a problem appears. Sustaining efficient and effective employee performance requires the manager's ongoing attention and involvement.

Evolution of skin grafting for treatment of burns: Reverdin pinch grafting to Tanner mesh grafting and beyond.

PubMed

Singh, Mansher; Nuutila, Kristo; Collins, K C; Huang, Anne

2017-09-01

Skin grafting is the current standard care in the treatment of full thickness burns. It was first described around 1500 BC but the vast majority of advancements have been achieved over the past 200 years. An extensive literature review was conducted on Pubmed, Medline and Google Scholar researching the evolution of skin grafting techniques. The authors concentrated on the major landmarks of skin grafting and also provide an overview of ongoing research efforts in this field. The major innovations of skin grafting include Reverdin pinch grafting, Ollier grafting, Thiersch grafting, Wolfe grafting, Padgett dermatome and modifications, Meek-wall microdermatome and Tanner mesh grafting. A brief description of the usage, advantages and limitations of each technique is included in the manuscript. Skin grafting technique have evolved significantly over past 200 years from Reverdin pinch grafting to modern day meshed skin grafts using powered dermatome. Increasing the expansion ratio and improving the cosmetic and functional outcome are the main focus of ongoing skin grafting research and emerging techniques (such as Integra ® , Recell ® , Xpansion ® ) are showing promise. Copyright © 2017 Elsevier Ltd and ISBI. All rights reserved.

Integrating Phosphorus Movement with Soil and Water Loss in the Daily Erosion Project

NASA Astrophysics Data System (ADS)

Sklenar, Tim; Perez-Bidegain, Mario; Cruse, Richard; Gelder, Brian; Herzmann, Daryl

2016-04-01

The Daily Erosion Project (DEP) is an ongoing modelling effort which is now in its second generation. DEP provides comprehensive and dynamic estimates of sediment delivery, soil erosion, and hill slope runoff for agricultural land areas across the Midwestern United States every day for Hydrologic Unit Code 12 (HUC 12) size watersheds. Results are posted every morning on the Internet at dailyerosion.org. Currently DEP covers all of Iowa and portions of Kansas and Minnesota, but expansion of coverage is ongoing. The integration of highly resolute spatial and temporal climate data, soil properties, crop rotation and residue management data affords the opportunity to test the effects of using multiple conservation practices on the transport and fate of water borne nutrients, especially phosphorus, on the Midwestern United States agricultural landscapes. Understanding the interaction of different environmental and land management practices on phosphorus movement will allow data from the DEP to guide conservation efforts as expansion continues into surrounding Midwestern states. The presentation will provide an overview of the DEP technology, including how input data are derived and used to make daily erosion estimates on over 200,000 flowpaths in the modelling area, as well as a discussion of the ongoing phosphorus transport modelling efforts and plans for future expansion (both land area and model functionality).

High Temperature Irradiation-Resistant Thermocouple Performance Improvements

DOE Office of Scientific and Technical Information (OSTI.GOV)

Joshua Daw; Joy Rempe; Darrell Knudson

2009-04-01

Traditional methods for measuring temperature in-pile degrade at temperatures above 1100 ºC. To address this instrumentation need, the Idaho National Laboratory (INL) developed and evaluated the performance of a high temperature irradiation-resistant thermocouple (HTIR-TC) that contains alloys of molybdenum and niobium. Data from high temperature (up to 1500 ºC) long duration (up to 4000 hours) tests and on-going irradiations at INL’s Advanced Test Reactor demonstrate the superiority of these sensors to commercially-available thermocouples. However, several options have been identified that could further enhance their reliability, reduce their production costs, and allow their use in a wider range of operating conditions.more » This paper presents results from on-going Idaho National Laboratory (INL)/University of Idaho (UI) efforts to investigate options to improve HTIR-TC ductility, reliability, and resolution by investigating specially-formulated alloys of molybdenum and niobium and alternate diameter thermoelements (wires). In addition, on-going efforts to evaluate alternate fabrication approaches, such as drawn and loose assembly techniques will be discussed. Efforts to reduce HTIR-TC fabrication costs, such as the use of less expensive extension cable will also be presented. Finally, customized HTIR-TC designs developed for specific customer needs will be summarized to emphasize the varied conditions under which these sensors may be used.« less

Enhancing Discovery, Search, and Access of NASA Hydrological Data by Leveraging GEOSS

NASA Technical Reports Server (NTRS)

Teng, William L.

2015-01-01

An ongoing NASA-funded project has removed a longstanding barrier to accessing NASA data (i.e., accessing archived time-step array data as point-time series) for selected variables of the North American and Global Land Data Assimilation Systems (NLDAS and GLDAS, respectively) and other EOSDIS (Earth Observing System Data Information System) data sets (e.g., precipitation, soil moisture). These time series (data rods) are pre-generated. Data rods Web services are accessible through the CUAHSI Hydrologic Information System (HIS) and the Goddard Earth Sciences Data and Information Services Center (GES DISC) but are not easily discoverable by users of other non-NASA data systems. The Global Earth Observation System of Systems (GEOSS) is a logical mechanism for providing access to the data rods. An ongoing GEOSS Water Services project aims to develop a distributed, global registry of water data, map, and modeling services cataloged using the standards and procedures of the Open Geospatial Consortium and the World Meteorological Organization. The ongoing data rods project has demonstrated the feasibility of leveraging the GEOSS infrastructure to help provide access to time series of model grid information or grids of information over a geographical domain for a particular time interval. A recently-begun, related NASA-funded ACCESS-GEOSS project expands on these prior efforts. Current work is focused on both improving the performance of the generation of on-the-fly (OTF) data rods and the Web interfaces from which users can easily discover, search, and access NASA data.

InTASC Model Core Teaching Standards and Learning Progressions for Teachers 1.0: A Resource for Ongoing Teacher Development

ERIC Educational Resources Information Center

Council of Chief State School Officers, 2013

2013-01-01

The Council of Chief State School Officers (CCSSO), through its Interstate Teacher Assessment and Support Consortium (InTASC), offers this set of combined resources that define and support ongoing teacher effectiveness to ensure students reach college and career ready standards. This document includes the "InTASC Model Core Teaching…

Current status and ongoing conservation efforts for the federally endangered species Pityopsis ruthii

USDA-ARS?s Scientific Manuscript database

Pityopsis ruthii is an endangered species endemic to the Hiwassee and Ocoee rivers in Tennessee. Due to limited information regarding biology and genetics of P. ruthii, our research over the past 6 years have focused on conservation and recovery efforts. Using applied and molecular techniques, a bas...

The Need for Large-Scale, Longitudinal Empirical Studies in Middle Level Education Research

ERIC Educational Resources Information Center

Mertens, Steven B.; Caskey, Micki M.; Flowers, Nancy

2016-01-01

This essay describes and discusses the ongoing need for large-scale, longitudinal, empirical research studies focused on middle grades education. After a statement of the problem and concerns, the essay describes and critiques several prior middle grades efforts and research studies. Recommendations for future research efforts to inform policy…

75 FR 82053 - Notification of a New Privacy Act System of Records, Effort to Outcomes-Case Management System...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-12-29

... to facilitate on-going tracking and management of these services, leading to greater self-sufficiency... Congress. Comments Due Date: January 28, 2011. ADDRESSES: Interested persons are invited to submit comments... SYSTEM NAME: Efforts to Outcome Case Management Tracking System for DHAP-Ike. SYSTEM LOCATION: Baltimore...

Standing for Just and Right Decisions: The Long, Slow Path to School Safety.

ERIC Educational Resources Information Center

LeCompte, Margaret D.

2000-01-01

Describes one high school's 20-year struggle to create a safe school environment following race riots and sexual harassment of young women. Notes that these ongoing efforts set the pattern for the school's current efforts to provide equal protection for gay, lesbian, bisexual, transgendered, and queer/questioning students. (SM)

International Multidisciplinary Learning: An Account of a Collaborative Effort among Three Higher Education Institutions

ERIC Educational Resources Information Center

Poh, Paul S. H.; Soetanto, Robby; Austin, Stephen; Adamu, Zulkifar A.

2014-01-01

Requiring students to complete their course assignments in partnership and in collaboration with students from other institutions is not commonplace teaching pedagogy. Even less so when they transcend disciplines and international borders. This paper presents a brief account of an ongoing collaborative effort between Ryerson University, Coventry…

EVA Communications Avionics and Informatics

NASA Technical Reports Server (NTRS)

Carek, David Andrew

2005-01-01

The Glenn Research Center is investigating and developing technologies for communications, avionics, and information systems that will significantly enhance extra vehicular activity capabilities to support the Vision for Space Exploration. Several of the ongoing research and development efforts are described within this presentation including system requirements formulation, technology development efforts, trade studies, and operational concept demonstrations.

Air pollution in India and related adverse respiratory health effects: past, present, and future directions.

PubMed

Khilnani, Gopi C; Tiwari, Pawan

2018-03-01

The review describes current status of air pollution in India, summarizes recent research on adverse health effects of ambient and household air pollution, and outlines the ongoing efforts and future actions required to improve air quality and reduce morbidity and mortality because of air pollution in India. Global burden of disease data analysis reveals more than one million premature deaths attributable to ambient air pollution in 2015 in India. More than one million additional deaths can be attributed to household air pollution. Particulate matter with diameter 2.5 μm or less has been causatively linked with most premature deaths. Acute respiratory tract infections, asthma, chronic obstructive pulmonary disease, exacerbations of preexisting obstructive airway disease and lung cancer are proven adverse respiratory effects of air pollution. Targeting air quality standards laid by WHO can significantly reduce morbidity and mortality because of air pollution in India. India is currently exposed to high levels of ambient and household air pollutants. Respiratory adverse effects of air pollution are significant contributors to morbidity and premature mortality in India. Substantial efforts are being made at legislative, administrative, and community levels to improve air quality. However, much more needs to be done to change the 'status quo' and attain the target air quality standards. VIDEO ABSTRACT: http://links.lww.com/COPM/A24.

LISA Beyond Einstein: From the Big Bang to Black Holes. LISA Technology Development at GSFC

NASA Technical Reports Server (NTRS)

Thorpe, James Ira

2008-01-01

This viewgraph presentation reviews the work that has been ongoing at the Goddard Space Flight Center (GSFC) in the development of the technology to be used in the Laser Interferometer Space Antenna (LISA) spacecrafts. The prime focus of LISA technology development efforts at NASA/GSFC has been in LISA interferometry. Specifically efforts have been made in the area of laser frequency noise mitigation. Laser frequency noise is addressed through a combination of stabilization and common-mode rejection. Current plans call for two stages of stabilization, pre-stabilization to a local frequency reference and further stabilization using the constellation as a frequency reference. In order for these techniques to be used simultaneously, the pre-stabilization step must provide an adjustable frequency offset. This presentation reports on a modification to the standard modulation/demodulation technique used to stabilize to optical cavities that generates a frequency-tunable reference from a fixed length cavity. This technique requires no modifications to the cavity itself and only minor modifications to the components. The measured noise performance and dynamic range of the laboratory prototype meet the LISA requirements.

Multi-jurisdictional environmental impact assessment: Canadian experiences

DOE Office of Scientific and Technical Information (OSTI.GOV)

Fitzpatrick, Patricia, E-mail: p.fitzpatrick@uwinnipeg.c; Sinclair, A. John, E-mail: Jsincla@ms.umanitoba.c

This research examines complexities surrounding environmental impact assessment (EIA) in a multi-jurisdictional environment, with a specific focus on opportunities for public participation. With almost universal adoption of EIA, projects are increasingly subject to more than one assessment process. Thus there is demand to facilitate inter-jurisdictional coordination of EIAs. Canada has growing expertise with multijuristictional EIA that serves to illustrate the costs and opportunities associated with three different approaches to coordination: standardization, harmonization and substitution. Findings suggest that, although fraught with issues, harmonization is the most realistic approach for coordinating efforts. Harmonization has the potential to minimize duplication, avoid process uncertaintymore » and increase efficiency and effectiveness in EIA. Furthermore, the analysis demonstrates that a bilateral agreement between jurisdictions is the best approach to harmonization, so long as negotiation of the agreement includes opportunities for meaningful participation, and implementation includes activities designed to communicate the assessment responsibilities of each jurisdiction, activities and schedules to the public. The experience of participants of different coordinated EIAs in Canada serves as counsel for on-going and future efforts to facilitate inter-jurisdictional coordination.« less

Analytical performance of 17 general chemistry analytes across countries and across manufacturers in the INPUtS project of EQA organizers in Italy, the Netherlands, Portugal, United Kingdom and Spain.

PubMed

Weykamp, Cas; Secchiero, Sandra; Plebani, Mario; Thelen, Marc; Cobbaert, Christa; Thomas, Annette; Jassam, Nuthar; Barth, Julian H; Perich, Carmen; Ricós, Carmen; Faria, Ana Paula

2017-02-01

Optimum patient care in relation to laboratory medicine is achieved when results of laboratory tests are equivalent, irrespective of the analytical platform used or the country where the laboratory is located. Standardization and harmonization minimize differences and the success of efforts to achieve this can be monitored with international category 1 external quality assessment (EQA) programs. An EQA project with commutable samples, targeted with reference measurement procedures (RMPs) was organized by EQA institutes in Italy, the Netherlands, Portugal, UK, and Spain. Results of 17 general chemistry analytes were evaluated across countries and across manufacturers according to performance specifications derived from biological variation (BV). For K, uric acid, glucose, cholesterol and high-density density (HDL) cholesterol, the minimum performance specification was met in all countries and by all manufacturers. For Na, Cl, and Ca, the minimum performance specifications were met by none of the countries and manufacturers. For enzymes, the situation was complicated, as standardization of results of enzymes toward RMPs was still not achieved in 20% of the laboratories and questionable in the remaining 80%. The overall performance of the measurement of 17 general chemistry analytes in European medical laboratories met the minimum performance specifications. In this general picture, there were no significant differences per country and no significant differences per manufacturer. There were major differences between the analytes. There were six analytes for which the minimum quality specifications were not met and manufacturers should improve their performance for these analytes. Standardization of results of enzymes requires ongoing efforts.

The Experiment Factory: Standardizing Behavioral Experiments.

PubMed

Sochat, Vanessa V; Eisenberg, Ian W; Enkavi, A Zeynep; Li, Jamie; Bissett, Patrick G; Poldrack, Russell A

2016-01-01

The administration of behavioral and experimental paradigms for psychology research is hindered by lack of a coordinated effort to develop and deploy standardized paradigms. While several frameworks (Mason and Suri, 2011; McDonnell et al., 2012; de Leeuw, 2015; Lange et al., 2015) have provided infrastructure and methods for individual research groups to develop paradigms, missing is a coordinated effort to develop paradigms linked with a system to easily deploy them. This disorganization leads to redundancy in development, divergent implementations of conceptually identical tasks, disorganized and error-prone code lacking documentation, and difficulty in replication. The ongoing reproducibility crisis in psychology and neuroscience research (Baker, 2015; Open Science Collaboration, 2015) highlights the urgency of this challenge: reproducible research in behavioral psychology is conditional on deployment of equivalent experiments. A large, accessible repository of experiments for researchers to develop collaboratively is most efficiently accomplished through an open source framework. Here we present the Experiment Factory, an open source framework for the development and deployment of web-based experiments. The modular infrastructure includes experiments, virtual machines for local or cloud deployment, and an application to drive these components and provide developers with functions and tools for further extension. We release this infrastructure with a deployment (http://www.expfactory.org) that researchers are currently using to run a set of over 80 standardized web-based experiments on Amazon Mechanical Turk. By providing open source tools for both deployment and development, this novel infrastructure holds promise to bring reproducibility to the administration of experiments, and accelerate scientific progress by providing a shared community resource of psychological paradigms.

The Experiment Factory: Standardizing Behavioral Experiments

PubMed Central

Sochat, Vanessa V.; Eisenberg, Ian W.; Enkavi, A. Zeynep; Li, Jamie; Bissett, Patrick G.; Poldrack, Russell A.

2016-01-01

The administration of behavioral and experimental paradigms for psychology research is hindered by lack of a coordinated effort to develop and deploy standardized paradigms. While several frameworks (Mason and Suri, 2011; McDonnell et al., 2012; de Leeuw, 2015; Lange et al., 2015) have provided infrastructure and methods for individual research groups to develop paradigms, missing is a coordinated effort to develop paradigms linked with a system to easily deploy them. This disorganization leads to redundancy in development, divergent implementations of conceptually identical tasks, disorganized and error-prone code lacking documentation, and difficulty in replication. The ongoing reproducibility crisis in psychology and neuroscience research (Baker, 2015; Open Science Collaboration, 2015) highlights the urgency of this challenge: reproducible research in behavioral psychology is conditional on deployment of equivalent experiments. A large, accessible repository of experiments for researchers to develop collaboratively is most efficiently accomplished through an open source framework. Here we present the Experiment Factory, an open source framework for the development and deployment of web-based experiments. The modular infrastructure includes experiments, virtual machines for local or cloud deployment, and an application to drive these components and provide developers with functions and tools for further extension. We release this infrastructure with a deployment (http://www.expfactory.org) that researchers are currently using to run a set of over 80 standardized web-based experiments on Amazon Mechanical Turk. By providing open source tools for both deployment and development, this novel infrastructure holds promise to bring reproducibility to the administration of experiments, and accelerate scientific progress by providing a shared community resource of psychological paradigms. PMID:27199843

Professional Development Strategies to Enhance Nurses' Knowledge and Maintain Safe Practice.

PubMed

Bindon, Susan L

2017-08-01

Maintaining competence is a professional responsibility for nurses. Individual nurses are accountable for their practice, as outlined in the American Nurses Association's Nursing: Scope and Standards of Practice. Nurses across clinical settings face the sometimes daunting challenge of staying abreast of regulatory mandates, practice changes, equipment updates, and other workplace expectations. In the complex, evolving perioperative setting, professional development is a priority, and the need for ongoing education is critical. However, nurses' efforts to engage in their own development can be hampered by a lack of time, limited access to educational resources, or cost concerns. This article provides an overview of nursing professional development and offers some resources to help individual nurses maintain or enhance their knowledge, skills, and attitudes. Copyright © 2017 AORN, Inc. Published by Elsevier Inc. All rights reserved.

Commercialization and Standardization Progress Towards an Optical Communications Earth Relay

NASA Technical Reports Server (NTRS)

Edwards, Bernard L.; Israel, David J.

2015-01-01

NASA is planning to launch the next generation of a space based Earth relay in 2025 to join the current Space Network, consisting of Tracking and Data Relay Satellites in space and the corresponding infrastructure on Earth. While the requirements and architecture for that relay satellite are unknown at this time, NASA is investing in communications technologies that could be deployed to provide new communications services. One of those new technologies is optical communications. The Laser Communications Relay Demonstration (LCRD) project, scheduled for launch in 2018 as a hosted payload on a commercial communications satellite, is a critical pathfinder towards NASA providing optical communications services on the next generation space based relay. This paper will describe NASA efforts in the on-going commercialization of optical communications and the development of inter-operability standards. Both are seen as critical to making optical communications a reality on future NASA science and exploration missions. Commercialization is important because NASA would like to eventually be able to simply purchase an entire optical communications terminal from a commercial provider. Inter-operability standards are needed to ensure that optical communications terminals developed by one vendor are compatible with the terminals of another. International standards in optical communications would also allow the space missions of one nation to use the infrastructure of another.

Towards the Third Wave of School Effectiveness and Improvement in Hong Kong: Internal, Interface and Future.

ERIC Educational Resources Information Center

Cheng, Yin Cheong

This presentation reports on three waves of reform efforts for school effectiveness and improvement in Hong Kong, and analyzes related challenges and issues with the hope of drawing international implications for ongoing research and reform efforts in different parts of the world. These three waves represent paradigm shifts and different…

A variable-instar climate-driven individual beetle-based phenology model for the invasive Asian longhorned beetle (Coleoptera: Cerambycidae)

Treesearch

R. Talbot Trotter, III; Melody A. Keena

2016-01-01

Efforts to manage and eradicate invasive species can benefit from an improved understanding of the physiology, biology, and behavior of the target species, and ongoing efforts to eradicate the Asian longhorned beetle (Anoplophora glabripennis Motschulsky) highlight the roles this information may play. Here, we present a climate-driven phenology...

Building and Sustaining Talent: Creating Conditions in High-Poverty Schools That Support Effective Teaching and Learning

ERIC Educational Resources Information Center

Almy, Sarah; Tooley, Melissa

2012-01-01

Improving teaching effectiveness is a hot topic for policymakers around the country these days. The gathering movement marks an important step forward in the ongoing effort to strengthen our nation's schools. In many cases, however, these efforts start and stop with improving outdated, inadequate teacher evaluation systems. Such approaches fail to…

DOE`s nation-wide system for access control can solve problems for the federal government

DOE Office of Scientific and Technical Information (OSTI.GOV)

Callahan, S.; Tomes, D.; Davis, G.

1996-07-01

The U.S. Department of Energy`s (DOE`s) ongoing efforts to improve its physical and personnel security systems while reducing its costs, provide a model for federal government visitor processing. Through the careful use of standardized badges, computer databases, and networks of automated access control systems, the DOE is increasing the security associated with travel throughout the DOE complex, and at the same time, eliminating paperwork, special badging, and visitor delays. The DOE is also improving badge accountability, personnel identification assurance, and access authorization timeliness and accuracy. Like the federal government, the DOE has dozens of geographically dispersed locations run by manymore » different contractors operating a wide range of security systems. The DOE has overcome these obstacles by providing data format standards, a complex-wide virtual network for security, the adoption of a standard high security system, and an open-systems-compatible link for any automated access control system. If the location`s level of security requires it, positive visitor identification is accomplished by personal identification number (PIN) and/or by biometrics. At sites with automated access control systems, this positive identification is integrated into the portals.« less

Adjudicative Competence

PubMed Central

Dawes, Sharron E.; Palmer, Barton W.; Jeste, Dilip V.

2008-01-01

Purpose of review Although the basic standards of adjudicative competence were specified by the U.S. Supreme Court in 1960, there remain a number of complex conceptual and practical issues in interpreting and applying these standards. In this report we provide a brief overview regarding the general concept of adjudicative competence and its assessment, as well as some highlights of recent empirical studies on this topic. Findings Most adjudicative competence assessments are conducted by psychiatrists or psychologists. There are no universal certification requirements, but some states are moving toward required certification of forensic expertise for those conducting such assessments. Recent data indicate inconsistencies in application of the existing standards even among forensic experts, but the recent publication of consensus guidelines may foster improvements in this arena. There are also ongoing efforts to develop and validate structured instruments to aid competency evaluations. Telemedicine-based competency interviews may facilitate evaluation by those with specific expertise for evaluation of complex cases. There is also interest in empirical development of educational methods to enhance adjudicative competence. Summary Adjudicative competence may be difficult to measure accurately, but the assessments and tools available are advancing. More research is needed on methods of enhancing decisional capacity among those with impaired competence. PMID:18650693

Risk of bias and confounding of observational studies of Zika virus infection: A scoping review of research protocols.

PubMed

Reveiz, Ludovic; Haby, Michelle M; Martínez-Vega, Ruth; Pinzón-Flores, Carlos E; Elias, Vanessa; Smith, Emma; Pinart, Mariona; Broutet, Nathalie; Becerra-Posada, Francisco; Aldighieri, Sylvain; Van Kerkhove, Maria D

2017-01-01

Given the severity and impact of the current Zika virus (ZIKV) outbreak in the Americas, numerous countries have rushed to develop research studies to assess ZIKV and its potential health consequences. In an effort to ensure that studies are comprehensive, both internally and externally valid, and with reliable results, the World Health Organization, the Pan American Health Organization, Institut Pasteur, the networks of Fiocruz, the Consortia for the Standardization of Influenza Seroepidemiology (CONSISE) and the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) have generated six standardized clinical and epidemiological research protocols and questionnaires to address key public health questions on ZIKV. We conducted a systematic search of ongoing study protocols related to ZIKV research. We analyzed the content of protocols of 32 cohort studies and 13 case control studies for systematic bias that could produce erroneous results. Additionally we aimed to characterize the risks of bias and confounding in observational studies related to ZIKV and to propose ways to minimize them, including the use of six newly standardized research protocols. Observational studies of ZIKV face an array of challenges, including measurement of exposure and outcomes (microcephaly and Guillain-Barré Syndrome). Potential confounders need to be measured where known and controlled for in the analysis. Selection bias due to non-random selection is a significant issue, particularly in the case-control design, and losses to follow-up is equally important for the cohort design. Observational research seeking to answer key questions on the ZIKV should consider these restrictions and take precautions to minimize bias in an effort to provide reliable and valid results. Utilization of the standardized research protocols developed by the WHO, PAHO, Institut Pasteur, and CONSISE will harmonize the key methodological aspects of each study design to minimize bias at different stages of the study. Biases need to be considered by researchers implementing the standardized protocols as well as by users of observational epidemiological studies of ZIKV.

USDA Gin Lab Updates

USDA-ARS?s Scientific Manuscript database

This presentation provides an update to ginning industry stakeholders on current research efforts ongoing at the three USDA ARS ginning laboratories in Lubbock, TX, Stoneville, MS, and Mesilla Park, NM....

TMDL Implementation: Lessons Learned

EPA Pesticide Factsheets

Virginia Tech Center for TMDL and Watershed Studies provided state TMDL implementation information and reviewed ongoing TMDL implementation efforts across the country to identify factors that contribute to successful implementation.

Human factors in waste management - potential and reality

DOE Office of Scientific and Technical Information (OSTI.GOV)

Thompson, J.S.

There is enormous potential for human factors contributions in the realm of waste management. The reality, however, is very different from the potential. This is particularly true for low-level and low-level mixed-waste management. The hazards are less severe; therefore, health and safety requirements (including human factors) are not as rigorous as for high-level waste. High-level waste management presents its own unique challenges and opportunities. Waste management is strongly driven by regulatory compliance. When regulations are flexible and open to interpretation and the environment is driven so strongly by regulatory compliance, standard practice is to drop {open_quotes}nice to have{close_quotes} features, likemore » a human factors program, to save money for complying with other requirements. The challenge is to convince decision makers that human factors can help make operations efficient and cost-effective, as well as improving safety and complying with regulations. A human factors program should not be viewed as competing with compliance efforts; in fact, it should complement them and provide additional cost-effective means of achieving compliance with other regulations. Achieving this synergy of human factors with ongoing waste management operations requires educating program and facility managers and other technical specialists about human factors and demonstrating its value {open_quotes}through the back door{close_quotes} on existing efforts. This paper describes ongoing projects at Los Alamos National Laboratory (LANL) in support of their waste management groups. It includes lessons learned from hazard and risk analyses, safety analysis reports, job and task analyses, operating procedure development, personnel qualification/certification program development, and facility- and job-specific training program and course development.« less

The Quality of Feeling.

ERIC Educational Resources Information Center

Wilkinson, Andrew

1985-01-01

Describes the efforts of the Crediton Project, an ongoing research project in Devon, England, to develop an assessment scheme that accounts for cognitive, affective, moral, and stylistic development in children's writing. (DF)

The Fukushima nuclear disaster is ongoing.

PubMed

Marks, Andrew R

2016-07-01

The 5th anniversary of the Fukushima disaster and the 30th anniversary of the Chernobyl disaster, the two most catastrophic nuclear accidents in history, both occurred recently. Images of Chernobyl are replete with the international sign of radioactive contamination (a circle with three broad spokes radiating outward in a yellow sign). In contrast, ongoing decontamination efforts at Fukushima lack international warnings about radioactivity. Decontamination workers at Fukushima appear to be poorly protected against radiation. It is almost as if the effort is to make the Fukushima problem disappear. A more useful response would be to openly acknowledge the monumental problems inherent in managing a nuclear plant disaster. Lessons from Chernobyl are the best predictors of what the Fukushima region of Japan is coping with in terms of health and environmental problems following a nuclear catastrophe.

Focus on cumulative emissions, global carbon budgets and the implications for climate mitigation targets

NASA Astrophysics Data System (ADS)

Damon Matthews, H.; Zickfeld, Kirsten; Knutti, Reto; Allen, Myles R.

2018-01-01

The Environmental Research Letters focus issue on ‘Cumulative Emissions, Global Carbon Budgets and the Implications for Climate Mitigation Targets’ was launched in 2015 to highlight the emerging science of the climate response to cumulative emissions, and how this can inform efforts to decrease emissions fast enough to avoid dangerous climate impacts. The 22 research articles published represent a fantastic snapshot of the state-or-the-art in this field, covering both the science and policy aspects of cumulative emissions and carbon budget research. In this Review and Synthesis, we summarize the findings published in this focus issue, outline some suggestions for ongoing research needs, and present our assessment of the implications of this research for ongoing efforts to meet the goals of the Paris climate agreement.

Future use of digital remote sensing data

NASA Technical Reports Server (NTRS)

Spann, G. W.; Jones, N. L.

1978-01-01

Users of remote sensing data are increasingly turning to digital processing techniques for the extraction of land resource, environmental, and natural resource information. This paper presents the results of recent and ongoing research efforts sponsored, in part, by NASA/Marshall Space Flight Center on the current uses of and future needs for digital remote sensing data. An ongoing investigation involves a comprehensive survey of capabilities for digital Landsat data use in the Southeastern U.S. Another effort consists of an evaluation of future needs for digital remote sensing data by federal, state, and local governments and the private sector. These needs are projected into the 1980-1985 time frame. Furthermore, the accelerating use of digital remote sensing data is not limited to the U.S. or even to the developed countries of the world.

Usefulness of a Competency-Based Reflective Portfolio for Student Learning on a Masters Health Promotion Programme

ERIC Educational Resources Information Center

McKenna, Verna; Connolly, Claire; Hodgins, Margaret

2011-01-01

Background: Efforts to identify core competencies within health promotion and health education have been on-going for a number of years. These efforts include work carried out by the International Union for Health Promotion and Education (IUHPE) in drawing up a draft list of 11 core competencies which were incorporated into the practice module on…

The cost of sustaining a patient-centered medical home: experience from 2 states.

PubMed

Magill, Michael K; Ehrenberger, David; Scammon, Debra L; Day, Julie; Allen, Tatiana; Reall, Andreu J; Sides, Rhonda W; Kim, Jaewhan

2015-09-01

As medical practices transform to patient-centered medical homes (PCMHs), it is important to identify the ongoing costs of maintaining these "advanced primary care" functions. A key required input is personnel effort. This study's objective was to assess direct personnel costs to practices associated with the staffing necessary to deliver PCMH functions as outlined in the National Committee for Quality Assurance Standards. We developed a PCMH cost dimensions tool to assess costs associated with activities uniquely required to maintain PCMH functions. We interviewed practice managers, nurse supervisors, and medical directors in 20 varied primary care practices in 2 states, guided by the tool. Outcome measures included categories of staff used to perform various PCMH functions, time and personnel costs, and whether practices were delivering PCMH functions. Costs per full-time equivalent primary care clinician associated with PCMH functions varied across practices with an average of $7,691 per month in Utah practices and $9,658 in Colorado practices. PCMH incremental costs per encounter were $32.71 in Utah and $36.68 in Colorado. The average estimated cost per member per month for an assumed panel of 2,000 patients was $3.85 in Utah and $4.83 in Colorado. Identifying costs of maintaining PCMH functions will contribute to effective payment reform and to sustainability of transformation. Maintenance and ongoing support of PCMH functions require additional time and new skills, which may be provided by existing staff, additional staff, or both. Adequate compensation for ongoing and substantial incremental costs is critical for practices to sustain PCMH functions. © 2015 Annals of Family Medicine, Inc.

The Cost of Sustaining a Patient-Centered Medical Home: Experience From 2 States

PubMed Central

Magill, Michael K.; Ehrenberger, David; Scammon, Debra L.; Day, Julie; Allen, Tatiana; Reall, Andreu J.; Sides, Rhonda W.; Kim, Jaewhan

2015-01-01

PURPOSE As medical practices transform to patient-centered medical homes (PCMHs), it is important to identify the ongoing costs of maintaining these “advanced primary care” functions. A key required input is personnel effort. This study’s objective was to assess direct personnel costs to practices associated with the staffing necessary to deliver PCMH functions as outlined in the National Committee for Quality Assurance Standards. METHODS We developed a PCMH cost dimensions tool to assess costs associated with activities uniquely required to maintain PCMH functions. We interviewed practice managers, nurse supervisors, and medical directors in 20 varied primary care practices in 2 states, guided by the tool. Outcome measures included categories of staff used to perform various PCMH functions, time and personnel costs, and whether practices were delivering PCMH functions. RESULTS Costs per full-time equivalent primary care clinician associated with PCMH functions varied across practices with an average of $7,691 per month in Utah practices and $9,658 in Colorado practices. PCMH incremental costs per encounter were $32.71 in Utah and $36.68 in Colorado. The average estimated cost per member per month for an assumed panel of 2,000 patients was $3.85 in Utah and $4.83 in Colorado. CONCLUSIONS Identifying costs of maintaining PCMH functions will contribute to effective payment reform and to sustainability of transformation. Maintenance and ongoing support of PCMH functions require additional time and new skills, which may be provided by existing staff, additional staff, or both. Adequate compensation for ongoing and substantial incremental costs is critical for practices to sustain PCMH functions. PMID:26371263

International classification of reliability for implanted cochlear implant receiver stimulators.

PubMed

Battmer, Rolf-Dieter; Backous, Douglas D; Balkany, Thomas J; Briggs, Robert J S; Gantz, Bruce J; van Hasselt, Andrew; Kim, Chong Sun; Kubo, Takeshi; Lenarz, Thomas; Pillsbury, Harold C; O'Donoghue, Gerard M

2010-10-01

To design an international standard to be used when reporting reliability of the implanted components of cochlear implant systems to appropriate governmental authorities, cochlear implant (CI) centers, and for journal editors in evaluating manuscripts involving cochlear implant reliability. The International Consensus Group for Cochlear Implant Reliability Reporting was assembled to unify ongoing efforts in the United States, Europe, Asia, and Australia to create a consistent and comprehensive classification system for the implanted components of CI systems across manufacturers. All members of the consensus group are from tertiary referral cochlear implant centers. None. A clinically relevant classification scheme adapted from principles of ISO standard 5841-2:2000 originally designed for reporting reliability of cardiac pacemakers, pulse generators, or leads. Standard definitions for device failure, survival time, clinical benefit, reduced clinical benefit, and specification were generated. Time intervals for reporting back to implant centers for devices tested to be "out of specification," categorization of explanted devices, the method of cumulative survival reporting, and content of reliability reports to be issued by manufacturers was agreed upon by all members. The methodology for calculating Cumulative survival was adapted from ISO standard 5841-2:2000. The International Consensus Group on Cochlear Implant Device Reliability Reporting recommends compliance to this new standard in reporting reliability of implanted CI components by all manufacturers of CIs and the adoption of this standard as a minimal reporting guideline for editors of journals publishing cochlear implant research results.

Developing tools for digital radar image data evaluation

NASA Technical Reports Server (NTRS)

Domik, G.; Leberl, F.; Raggam, J.

1986-01-01

The refinement of radar image analysis methods has led to a need for a systems approach to radar image processing software. Developments stimulated through satellite radar are combined with standard image processing techniques to create a user environment to manipulate and analyze airborne and satellite radar images. One aim is to create radar products for the user from the original data to enhance the ease of understanding the contents. The results are called secondary image products and derive from the original digital images. Another aim is to support interactive SAR image analysis. Software methods permit use of a digital height model to create ortho images, synthetic images, stereo-ortho images, radar maps or color combinations of different component products. Efforts are ongoing to integrate individual tools into a combined hardware/software environment for interactive radar image analysis.

The Legacy Archive for Microwave Background Data Analysis (LAMBDA)

NASA Astrophysics Data System (ADS)

Miller, Nathan; LAMBDA

2018-01-01

The Legacy Archive for Microwave Background Data Analysis (LAMBDA) provides CMB researchers with archival data for cosmology missions, software tools, and links to other sites of interest. LAMBDA is one-stop shopping for CMB researchers. It hosts data from WMAP along with many suborbital experiments. Over the past year, LAMBDA has acquired new data from SPTpol, SPIDER and ACTPol. In addition to the primary CMB, LAMBDA also provides foreground data.LAMBDA has several ongoing efforts to provide tools for CMB researchers. These tools include a web interface for CAMB and a web interface for a CMB survey footprint database and plotting tool. Additionally, we have recently developed a Docker container with standard CMB analysis tools and demonstrations in the form of Jupyter notebooks. These containers will be publically available through Docker's container repository and the source will be available on github.

Cassini's Test Methodology for Flight Software Verification and Operations

NASA Technical Reports Server (NTRS)

Wang, Eric; Brown, Jay

2007-01-01

The Cassini spacecraft was launched on 15 October 1997 on a Titan IV-B launch vehicle. The spacecraft is comprised of various subsystems, including the Attitude and Articulation Control Subsystem (AACS). The AACS Flight Software (FSW) and its development has been an ongoing effort, from the design, development and finally operations. As planned, major modifications to certain FSW functions were designed, tested, verified and uploaded during the cruise phase of the mission. Each flight software upload involved extensive verification testing. A standardized FSW testing methodology was used to verify the integrity of the flight software. This paper summarizes the flight software testing methodology used for verifying FSW from pre-launch through the prime mission, with an emphasis on flight experience testing during the first 2.5 years of the prime mission (July 2004 through January 2007).

2017 State of Wind Development in the United States by Region

DOE Office of Scientific and Technical Information (OSTI.GOV)

Oteri, Frank A; Baranowski, Ruth E; Baring-Gould, Edward I

This document summarizes the status and drivers for U.S. wind energy development during 2017. Regional Resource Center (RRC) leaders provided a report of wind energy development in their regions, which was combined with findings from National Renewable Energy Laboratory (NREL) researchers to provide an account of the state of the regions, as well as updates on developments in individual states. NREL researchers and state partners added updates for all states that are not directly supported by an RRC. Accounts for each region include updates on renewable portfolio standards, workforce development, manufacturing and economic development, and individual state updates for installedmore » wind capacity, ongoing policy developments, planned projects and their status, transmission progress reports, etc. This report also highlights the efforts of the RRCs to engage stakeholders in their individual regions.« less

Design considerations for a 10-kW integrated hydrogen-oxygen regenerative fuel cell system

NASA Technical Reports Server (NTRS)

Hoberecht, M. A.; Miller, T. B.; Rieker, L. L.; Gonzalez-Sanabria, O. D.

1984-01-01

Integration of an alkaline fuel cell subsystem with an alkaline electrolysis subsystem to form a regenerative fuel cell (RFC) system for low earth orbit (LEO) applications characterized by relatively high overall round trip electrical efficiency, long life, and high reliability is possible with present state of the art technology. A hypothetical 10 kW system computer modeled and studied based on data from ongoing contractual efforts in both the alkaline fuel cell and alkaline water electrolysis areas. The alkaline fuel cell technology is under development utilizing advanced cell components and standard Shuttle Orbiter system hardware. The alkaline electrolysis technology uses a static water vapor feed technique and scaled up cell hardware is developed. The computer aided study of the performance, operating, and design parameters of the hypothetical system is addressed.

A preliminary look at techniques used to obtain airdata from flight at high angles of attack

NASA Technical Reports Server (NTRS)

Moes, Timothy R.; Whitmore, Stephen A.

1990-01-01

Flight research at high angles of attack has posed new problems for airdata measurements. New sensors and techniques for measuring the standard airdata quantities of static pressure, dynamic pressure, angle of attack, and angle of sideslip were subsequently developed. The ongoing airdata research supporting NASA's F-18 high alpha research program is updated. Included are the techniques used and the preliminary results. The F-18 aircraft was flown with three research airdata systems: a standard airdata probe on the right wingtip, a self-aligning airdata probe on the left wingtip, and a flush airdata system on the nose cone. The primary research goal was to obtain steady-state calibrations for each airdata system up to an angle of attack of 50 deg. This goal was accomplished and preliminary accuracies of the three airdata systems were assessed and are presented. An effort to improve the fidelity of the airdata measurements during dynamic maneuvering is also discussed. This involved enhancement of the aerodynamic data with data obtained from linear accelerometers, rate gyros, and attitude gyros. Preliminary results of this technique are presented.

IDAHO NATIONAL LABORATORY TRANSPORTATION TASK REPORT ON ACHIEVING MODERATOR EXCLUSION AND SUPPORTING STANDARDIZED TRANSPORTATION

DOE Office of Scientific and Technical Information (OSTI.GOV)

D.K. Morton

2011-09-01

Following the defunding of the Yucca Mountain Project, it is reasonable to assume that commercial used fuel will remain in storage for the foreseeable future. This report proposes supplementing the ongoing research and development work related to potential degradation of used fuel, baskets, poisons, and storage canisters during an extended period of storage with a parallel path. This parallel path can assure criticality safety during transportation by implementing a concept that achieves moderator exclusion (no in-leakage of moderator into the used fuel cavity). Using updated risk assessment insights for additional technical justification and relying upon a component inside of themore » transportation cask that provides a watertight function, a strong argument can be made that moderator intrusion is not credible and should not be a required assumption for criticality evaluations during normal conditions of transportation. A demonstrating testing program supporting a detailed analytical effort as well as updated risk assessment insights can provide the basis for moderator exclusion during hypothetical accident conditions. This report also discusses how this engineered concept can support the goal of standardized transportation.« less

Experimenting with an Evolving Ground/Space-based Software Architecture to Enable Sensor Webs

NASA Technical Reports Server (NTRS)

mandl, Daniel; Frye, Stuart

2005-01-01

A series of ongoing experiments are being conducted at the NASA Goddard Space Flight Center to explore integrated ground and space-based software architectures enabling sensor webs. A sensor web, as defined by Steve Talabac at NASA Goddard Space Flight Center(GSFC), is a coherent set of distributed nodes interconnected by a communications fabric, that collectively behave as a single, dynamically adaptive, observing system. The nodes can be comprised of satellites, ground instruments, computing nodes etc. Sensor web capability requires autonomous management of constellation resources. This becomes progressively more important as more and more satellites share resource, such as communication channels and ground station,s while automatically coordinating their activities. There have been five ongoing activities which include an effort to standardize a set of middleware. This paper will describe one set of activities using the Earth Observing 1 satellite, which used a variety of ground and flight software along with other satellites and ground sensors to prototype a sensor web. This activity allowed us to explore where the difficulties that occur in the assembly of sensor webs given today s technology. We will present an overview of the software system architecture, some key experiments and lessons learned to facilitate better sensor webs in the future.

Hotel shows health system keys to service excellence.

PubMed

2003-08-01

Ritz-Carlton partnership part of broader program pursuing service excellence. Nearly 600 system leaders will participate in day-long seminars. GE, Harvard serve as strategic partners for ongoing educational efforts.

Using Public Reports of Patient Satisfaction for Hospital Quality Improvement

PubMed Central

Barr, Judith K; Giannotti, Tierney E; Sofaer, Shoshanna; Duquette, Cathy E; Waters, William J; Petrillo, Marcia K

2006-01-01

Objective To explore the impact of statewide public reporting of hospital patient satisfaction on hospital quality improvement (QI), using Rhode Island (RI) as a case example. Data Source Primary data collected through semi-structured interviews between September 2002 and January 2003. Study Design The design is a retrospective study of hospital executives at all 11 general and two specialty hospitals in RI. Respondents were asked about hospital QI activities at several points throughout the public reporting process, as well as about hospital structure and processes to accomplish QI. Qualitative analysis of the interview data proceeded through an iterative process to identify themes and categories in the data. Principal Findings Data from the standardized statewide patient satisfaction survey process were used by hospitals to identify and target new QI initiatives, evaluate performance, and monitor progress. While all hospitals fully participated in the public reporting process, they varied in the stage of development of their QI activities and adoption of the statewide standardized survey for ongoing monitoring of their QI programs. Most hospitals placed responsibility for QI within each department, with results reported to top management, who were perceived as giving strong support for QI. The external environment facilitated QI efforts. Conclusion Public reporting of comparative data on patient views can enhance and reinforce QI efforts in hospitals. The participation of key stakeholders facilitated successful implementation of statewide public reporting. This experience in RI offers lessons for other states or regions as they move to public reporting of hospital quality data. PMID:16704506

Crash Modification Factors Needs Assessment Workshop

DOT National Transportation Integrated Search

2015-03-01

The Federal Highway Administration (FHWA) hosted a Crash Modification Factor (CMF) Stakeholder Meeting to provide a forum for CMF stakeholders to communicate ongoing efforts and identify opportunities for future collaboration. CMF stakeholders repres...

Coast Guard Polar Icebreaker Modernization: Background and Issues for Congress

DTIC Science & Technology

2013-04-25

Accountability Office, Coast Guard[:]Efforts to Identify Arctic Requirements Are Ongoing, but More Communication about Agency Planning Efforts Would...control, and communications capabilities. The flexibility and mobility of polar icebreakers would assist the Coast Guard in closing future mission...Sea to prevent foreign fishing in U.S. waters and overfishing —Capability to conduct search and rescue in Beaufort Sea for cruise line and natural

Coast Guard Polar Icebreaker Modernization: Background and Issues for Congress

DTIC Science & Technology

2014-02-11

Efforts to Identify Arctic Requirements Are Ongoing, but More Communication about Agency Planning Efforts Would Be Beneficial, GAO-10- 870, September...icebreakers also have substantial command, control, and communications capabilities. The flexibility and mobility of polar icebreakers would assist...Fisheries enforcement in Bering Sea to prevent foreign fishing in U.S. waters and overfishing —Capability to conduct search and rescue in Beaufort Sea

Te Reo Maori as a Subject: The Impact of Language Ideology, Language Practice, and Language Management on Secondary School Students' Decision Making

ERIC Educational Resources Information Center

Jeurissen, Maree

2014-01-01

Te reo Maori, the Indigenous language of Aotearoa (New Zealand), remains 'endangered' despite concentrated ongoing efforts to reverse declining numbers of speakers. Most of these efforts have focused on te reo Maori immersion education settings as these were considered the most effective means to ensure the survival of the language (May &…

Transformation and Decolonisation of Mathematics Education for Sustainable Development: A Case Study of Its Learning Trend in Nigeria

ERIC Educational Resources Information Center

Salami, I. A.; Okeke, C. I. O.

2017-01-01

The quest to contextualise education in Africa has been on-going for a while and many countries have been making efforts towards it. During this time of educational review, conscious efforts should be made to identify problematic levels of some subjects that are dreadful to the learners to pave the way for curriculum re-design for context…

A Tale of Two Archives: PDS3/PDS4 Archiving and Distribution of Juno Mission Data

NASA Astrophysics Data System (ADS)

Stevenson, Zena; Neakrase, Lynn; Huber, Lyle; Chanover, Nancy J.; Beebe, Reta F.; Sweebe, Kathrine; Johnson, Joni J.

2017-10-01

The Juno mission to Jupiter, which was launched on 5 August 2011 and arrived at the Jovian system in July 2016, represents the last mission to be officially archived under the PDS3 archive standards. Modernization and availability of the newer PDS4 archive standard has prompted the PDS Atmospheres Node (ATM) to provide on-the-fly migration of Juno data from PDS3 to PDS4. Data distribution under both standards presents challenges in terms of how to present data to the end user in both standards, without sacrificing accessibility to the data or impacting the active PDS3 mission pipelines tasked with delivering the data on predetermined schedules. The PDS Atmospheres Node has leveraged its experience with prior active PDS4 missions (e.g., LADEE and MAVEN) and ongoing PDS3-to-PDS4 data migration efforts providing a seamless distribution of Juno data in both PDS3 and PDS4. When ATM receives a data delivery from the Juno Science Operations Center, the PDS3 labels are validated and then fed through PDS4 migration software built at ATM. Specifically, a collection of Python methods and scripts has been developed to make the migration process as automatic as possible, even when working with the more complex labels used by several of the Juno instruments. This is used to create all of the PDS4 data labels at once and build PDS4 archive bundles with minimal human effort. Resultant bundles are then validated against the PDS4 standard and released alongside the certified PDS3 versions of the same data. The newer design of the distribution pages provides access to both versions of the data, utilizing some of the enhanced capabilities of PDS4 to improve search and retrieval of Juno data. Webpages are designed with the intent of offering easy access to all documentation for Juno data as well as the data themselves in both standards for users of all experience levels. We discuss the structure and organization of the Juno archive and associated webpages as examples of joint PDS3/PDS4 data access for end users.

Test Protocols for Advanced Inverter Interoperability Functions – Main Document

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Jay Dean; Gonzalez, Sigifredo; Ralph, Mark E.

2013-11-01

Distributed energy resources (DER) such as photovoltaic (PV) systems, when deployed in a large scale, are capable of influencing significantly the operation of power systems. Looking to the future, stakeholders are working on standards to make it possible to manage the potentially complex interactions between DER and the power system. In 2009, the Electric Power Research Institute (EPRI), Sandia National Laboratories (SNL) with the U.S. Department of Energy (DOE), and the Solar Electric Power Association (SEPA) initiated a large industry collaborative to identify and standardize definitions for a set of DER grid support functions. While the initial effort concentrated onmore » grid-tied PV inverters and energy storage systems, the concepts have applicability to all DER. A partial product of this on-going effort is a reference definitions document (IEC TR 61850-90-7, Object models for power converters in distributed energy resources (DER) systems) that has become a basis for expansion of related International Electrotechnical Commission (IEC) standards, and is supported by US National Institute of Standards and Technology (NIST) Smart Grid Interoperability Panel (SGIP). Some industry-led organizations advancing communications protocols have also embraced this work. As standards continue to evolve, it is necessary to develop test protocols to independently verify that the inverters are properly executing the advanced functions. Interoperability is assured by establishing common definitions for the functions and a method to test compliance with operational requirements. This document describes test protocols developed by SNL to evaluate the electrical performance and operational capabilities of PV inverters and energy storage, as described in IEC TR 61850-90-7. While many of these functions are not currently required by existing grid codes or may not be widely available commercially, the industry is rapidly moving in that direction. Interoperability issues are already apparent as some of these inverter capabilities are being incorporated in large demonstration and commercial projects. The test protocols are intended to be used to verify acceptable performance of inverters within the standard framework described in IEC TR 61850-90-7. These test protocols, as they are refined and validated over time, can become precursors for future certification test procedures for DER advanced grid support functions.« less

Test Protocols for Advanced Inverter Interoperability Functions - Appendices

DOE Office of Scientific and Technical Information (OSTI.GOV)

Johnson, Jay Dean; Gonzalez, Sigifredo; Ralph, Mark E.

2013-11-01

Distributed energy resources (DER) such as photovoltaic (PV) systems, when deployed in a large scale, are capable of influencing significantly the operation of power systems. Looking to the future, stakeholders are working on standards to make it possible to manage the potentially complex interactions between DER and the power system. In 2009, the Electric Power Research Institute (EPRI), Sandia National Laboratories (SNL) with the U.S. Department of Energy (DOE), and the Solar Electric Power Association (SEPA) initiated a large industry collaborative to identify and standardize definitions for a set of DER grid support functions. While the initial effort concentrated onmore » grid-tied PV inverters and energy storage systems, the concepts have applicability to all DER. A partial product of this on-going effort is a reference definitions document (IEC TR 61850-90-7, Object models for power converters in distributed energy resources (DER) systems) that has become a basis for expansion of related International Electrotechnical Commission (IEC) standards, and is supported by US National Institute of Standards and Technology (NIST) Smart Grid Interoperability Panel (SGIP). Some industry-led organizations advancing communications protocols have also embraced this work. As standards continue to evolve, it is necessary to develop test protocols to independently verify that the inverters are properly executing the advanced functions. Interoperability is assured by establishing common definitions for the functions and a method to test compliance with operational requirements. This document describes test protocols developed by SNL to evaluate the electrical performance and operational capabilities of PV inverters and energy storage, as described in IEC TR 61850-90-7. While many of these functions are not now required by existing grid codes or may not be widely available commercially, the industry is rapidly moving in that direction. Interoperability issues are already apparent as some of these inverter capabilities are being incorporated in large demonstration and commercial projects. The test protocols are intended to be used to verify acceptable performance of inverters within the standard framework described in IEC TR 61850-90-7. These test protocols, as they are refined and validated over time, can become precursors for future certification test procedures for DER advanced grid support functions.« less

Discovery of Emerging Per-and Polyfluoroalkyl Substances

EPA Science Inventory

Legacy perfluorinated compounds exhibit significant environmental persistence and bioaccumulation potential, which has spawned an ongoing effort to introduce replacement compounds with reduced toxicological risk profiles. Many of these emerging chemical species lack validated qua...

University Transportation Center : administration manual.

DOT National Transportation Integrated Search

2013-01-01

University Transportation Centers (UTCs) were established by the U.S. Department of : Transportation (USDOT) in 1987. UTCs are part of an on-going federal government effort to : improve transportation research, transportation education and to stre...

Superfund Program Review

EPA Pesticide Factsheets

This document presents outcomes of implementing a number of the actions described in the November 2013 Superfund Remedial Program Review (SPR) Action Plan . It also describes ongoing Action Plan efforts and projects future outcomes anticipated in FY 2015

Bio-engineering for land stabilization : final report.

DOT National Transportation Integrated Search

2010-06-01

As part of the Ohio Department of Transportations (ODOTs) ongoing effort to solve engineering problems for the Ohio : transportation system through research, The Ohio State University has undertaken a study entitled Bioengineering for : Land...

FY 1998-2002 proposed airport improvement program

DOT National Transportation Integrated Search

1997-05-01

For Fiscal Years 1998 through 2002, the Illinois Department of Transportation's : Airport Improvement Program includes ongoing efforts to resolve the aircraft : congestion problems in both the Chicago and St. Louis metropolitan areas. In : addition, ...

Evaluation and Analysis of F-16XL Wind Tunnel Data From Static and Dynamic Tests

NASA Technical Reports Server (NTRS)

Kim, Sungwan; Murphy, Patrick C.; Klein, Vladislav

2004-01-01

A series of wind tunnel tests were conducted in the NASA Langley Research Center as part of an ongoing effort to develop and test mathematical models for aircraft rigid-body aerodynamics in nonlinear unsteady flight regimes. Analysis of measurement accuracy, especially for nonlinear dynamic systems that may exhibit complicated behaviors, is an essential component of this ongoing effort. In this report, tools for harmonic analysis of dynamic data and assessing measurement accuracy are presented. A linear aerodynamic model is assumed that is appropriate for conventional forced-oscillation experiments, although more general models can be used with these tools. Application of the tools to experimental data is demonstrated and results indicate the levels of uncertainty in output measurements that can arise from experimental setup, calibration procedures, mechanical limitations, and input errors.

Equality in Healthcare: The Formation and Ongoing Legacy of an LGBT Advisory Council.

PubMed

Rosa, William; Fullerton, Chelsea; Keller, Ronald

2015-12-01

This article provides a broad overview of the literature on lesbian, gay, bisexual, transgender (LGBT) health disparities and workplace discrimination, as well as the context that led to the formation of an institutional LGBT Advisory Council. The Council was developed in order to demonstrate our ongoing commitment to LGBT inclusion and to improve the lived experiences for both LGBT patients and staff. A retrospective approach is utilized to explore the LGBT Advisory Council's journey to spearhead advocacy efforts at our institution. The Council's accomplishments include taking a leadership role in obtaining nationally recognized designations such as the Healthcare Equality Index and the Magnet Exemplar for Cultural Sensitivity, as well as adding sexual orientation, gender identity, and gender expression fields to our institution's electronic medical record system. Additionally, the Council guides and promotes ongoing house-wide cultural sensitivity staff training efforts. Most recently, the Council marched as a contingency in the world's largest Pride March for the first time in institutional history. It is our hope that our Council will become an inspiration and exemplar for similar groups to form at healthcare institutions and organizations across the nation. Allowing LGBT members of each individual healthcare community the agency to determine the direction of advocacy efforts is incredibly important; however, this must be coupled with an organizational commitment on behalf of leadership to follow through on these initiatives and to provide them with the resources they need in order to be successful.

Urushiol Patch Test Using the T.R.U.E. TEST System.

PubMed

Kim, Yesul; Longenecker, Amy; ElSohly, Mahmoud A; Gul, Waseem; Hage, Raymond J; Hamann, Curtis P; Marks, James G

Poison ivy, poison oak, and poison sumac are the most common causes of allergic contact dermatitis in North America. Although extensive efforts have been made to develop therapies that prevent and treat allergic contact dermatitis to these plants, there lacks an entirely effective method, besides complete avoidance. Efforts to develop a more effective preventive therapy, such as a vaccine, are ongoing. To accurately evaluate the efficacy of these new therapies, an appropriate assessment tool is needed. The aim of this study was to evaluate the safety and appropriate doses of urushiol required for a patch test based on the hydrogel delivery system of the Thin-Layer Rapid Use Epicutaneous Patch Test. Nine subjects were patch tested with various doses of urushiol and a negative control on day 0. Patch test sites were inspected for any local reaction on days 2, 4, 7, 14, and 21 after the initial exposure and graded by standard morphology. All 9 subjects did not have any significant adverse effects. The urushiol patch test using the hydrogel delivery method demonstrated urushiol sensitivity. All doses of urushiol resulted in a local reaction, and severity of reactions was correlated with dosage of urushiol used in the patch test.

Conceptualizing a Genomics Software Institute (GSI)

PubMed Central

Gilbert, Jack A.; Catlett, Charlie; Desai, Narayan; Knight, Rob; White, Owen; Robbins, Robert; Sankaran, Rajesh; Sansone, Susanna-Assunta; Field, Dawn; Meyer, Folker

2012-01-01

Microbial ecology has been enhanced greatly by the ongoing ‘omics revolution, bringing half the world's biomass and most of its biodiversity into analytical view for the first time; indeed, it feels almost like the invention of the microscope and the discovery of the new world at the same time. With major microbial ecology research efforts accumulating prodigious quantities of sequence, protein, and metabolite data, we are now poised to address environmental microbial research at macro scales, and to begin to characterize and understand the dimensions of microbial biodiversity on the planet. What is currently impeding progress is the need for a framework within which the research community can develop, exchange and discuss predictive ecosystem models that describe the biodiversity and functional interactions. Such a framework must encompass data and metadata transparency and interoperation; data and results validation, curation, and search; application programming interfaces for modeling and analysis tools; and human and technical processes and services necessary to ensure broad adoption. Here we discuss the need for focused community interaction to augment and deepen established community efforts, beginning with the Genomic Standards Consortium (GSC), to create a science-driven strategic plan for a Genomic Software Institute (GSI). PMID:22675605

ASRS Reports on Wake Vortex Encounters

NASA Technical Reports Server (NTRS)

Connell, Linda J.; Taube, Elisa Ann; Drew, Charles Robert; Barclay, Tommy Earl

2010-01-01

ASRS is conducting a structured callback research project of wake vortex incidents reported to the ASRS at all US airports, as well as wake encounters in the enroute environment. This study has three objectives: (1) Utilize the established ASRS supplemental data collection methodology and provide ongoing analysis of wake vortex encounter reports; (2) Document event dynamics and contributing factors underlying wake vortex encounter events; and (3) Support ongoing FAA efforts to address pre-emptive wake vortex risk reduction by utilizing ASRS reporting contributions.

Automated Processing and Evaluation of Anti-Nuclear Antibody Indirect Immunofluorescence Testing.

PubMed

Ricchiuti, Vincent; Adams, Joseph; Hardy, Donna J; Katayev, Alexander; Fleming, James K

2018-01-01

Indirect immunofluorescence (IIF) is considered by the American College of Rheumatology (ACR) and the international consensus on ANA patterns (ICAP) the gold standard for the screening of anti-nuclear antibodies (ANA). As conventional IIF is labor intensive, time-consuming, subjective, and poorly standardized, there have been ongoing efforts to improve the standardization of reagents and to develop automated platforms for assay incubation, microscopy, and evaluation. In this study, the workflow and performance characteristics of a fully automated ANA IIF system (Sprinter XL, EUROPattern Suite, IFA 40: HEp-20-10 cells) were compared to a manual approach using visual microscopy with a filter device for single-well titration and to technologist reading. The Sprinter/EUROPattern system enabled the processing of large daily workload cohorts in less than 8 h and the reduction of labor hands-on time by more than 4 h. Regarding the discrimination of positive from negative samples, the overall agreement of the EUROPattern software with technologist reading was higher (95.6%) than when compared to the current method (89.4%). Moreover, the software was consistent with technologist reading in 80.6-97.5% of patterns and 71.0-93.8% of titers. In conclusion, the Sprinter/EUROPattern system provides substantial labor savings and good concordance with technologist ANA IIF microscopy, thus increasing standardization, laboratory efficiency, and removing subjectivity.

Automated Processing and Evaluation of Anti-Nuclear Antibody Indirect Immunofluorescence Testing

PubMed Central

Ricchiuti, Vincent; Adams, Joseph; Hardy, Donna J.; Katayev, Alexander; Fleming, James K.

2018-01-01

Indirect immunofluorescence (IIF) is considered by the American College of Rheumatology (ACR) and the international consensus on ANA patterns (ICAP) the gold standard for the screening of anti-nuclear antibodies (ANA). As conventional IIF is labor intensive, time-consuming, subjective, and poorly standardized, there have been ongoing efforts to improve the standardization of reagents and to develop automated platforms for assay incubation, microscopy, and evaluation. In this study, the workflow and performance characteristics of a fully automated ANA IIF system (Sprinter XL, EUROPattern Suite, IFA 40: HEp-20-10 cells) were compared to a manual approach using visual microscopy with a filter device for single-well titration and to technologist reading. The Sprinter/EUROPattern system enabled the processing of large daily workload cohorts in less than 8 h and the reduction of labor hands-on time by more than 4 h. Regarding the discrimination of positive from negative samples, the overall agreement of the EUROPattern software with technologist reading was higher (95.6%) than when compared to the current method (89.4%). Moreover, the software was consistent with technologist reading in 80.6–97.5% of patterns and 71.0–93.8% of titers. In conclusion, the Sprinter/EUROPattern system provides substantial labor savings and good concordance with technologist ANA IIF microscopy, thus increasing standardization, laboratory efficiency, and removing subjectivity. PMID:29780386

Herbivory Network: An international, collaborative effort to study herbivory in Arctic and alpine ecosystems

NASA Astrophysics Data System (ADS)

Barrio, I. C.; Hik, D. S.; Jónsdóttir, I. S.; Bueno, C. G.; Mörsdorf, M. A.; Ravolainen, V. T.

2016-09-01

Plant-herbivore interactions are central to the functioning of tundra ecosystems, but their outcomes vary over space and time. Accurate forecasting of ecosystem responses to ongoing environmental changes requires a better understanding of the processes responsible for this heterogeneity. To effectively address this complexity at a global scale, coordinated research efforts, including multi-site comparisons within and across disciplines, are needed. The Herbivory Network was established as a forum for researchers from Arctic and alpine regions to collaboratively investigate the multifunctional role of herbivores in these changing ecosystems. One of the priorities is to integrate sites, methodologies, and metrics used in previous work, to develop a set of common protocols and design long-term geographically-balanced, coordinated experiments. The implementation of these collaborative research efforts will also improve our understanding of traditional human-managed systems that encompass significant portions of the sub-Arctic and alpine areas worldwide. A deeper understanding of the role of herbivory in these systems under ongoing environmental changes will guide appropriate adaptive strategies to preserve their natural values and related ecosystem services.

Quality assurance guides health reform in Jordan.

PubMed

Abubaker, W; Abdulrahman, M

1996-01-01

In November 1995, a World Bank mission went to Jordan to conduct a study of the health sector. The study recommended three strategies to reform the health sector: decentralization of Ministry of Health (MOH) management; improvement of clinical practices, quality of care, and consumer satisfaction; and adoption of treatment protocols and standards. The MOH chose quality assurance (QA) methods and quality management (QM) techniques to accomplish these reforms. The Monitoring and QA Directorate oversees QA applications within MOH. It also institutes and develops the capacity of local QA units in the 12 governorates. The QA units implement and monitor day-to-day QA activities. The QM approach encompasses quality principles: establish objectives; use a systematic approach; teach lessons learned and applicable research; use QA training to teach quality care, quality improvement, and patient satisfaction; educate health personnel about QM approaches; use assessment tools and interviews; measure the needs and expectations of local health providers and patients; ensure feedback on QA improvement projects; ensure valid and reliable data; monitor quality improvement efforts; standardize systemic data collection and outcomes; and establish and disseminate QA standards and performance improvement efforts. The Jordan QA Project has helped with the successful institutionalization of a QA system at both the central and local levels. The bylaws of the QA councils and committees require team participation in the decision-making process. Over the last two years, the M&QA Project has adopted 21 standards for nursing, maternal and child health care centers, pharmacies, and medications. The Balqa pilot project has developed 44 such protocols. Quality improvement (COUGH) studies have examined hyper-allergy, analysis of patient flow rate, redistribution of nurses, vaccine waste, and anemic pregnant women. There are a considerable number of on-going clinical and non-clinical COUGH studies. Four epidemiological studies are examining maternal mortality, causes of death, morbidity, and perinatal mortality.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Montellano, B.O. de

This report describes later stages of a program to develop culturally relevant science and math programs for Hispanic students. Part of this effort was follow-up with 17 teachers who participated in early stages of the program. Response was not very good. Included with the report is a first draft effort for curriculum materials which could be used as is in such a teaching effort. Several of the participating teachers were invited to a writing workshop, where lesson plans were drafted, and critiqued and following rework are listed in this publication. Further work needs to be completed and is ongoing.

METAL PARTITIONING IN COMBUSTION PROCESSES

EPA Science Inventory

This article summarizes ongoing research efforts at the National Risk Management Research Laboratory of the U.S. Environmental Protection Agency examining [high temperature] metal behavior within combustion environments. The partitioning of non-volatile (Cr and Ni), semi-volatil...

Low-cost, distributed, sensor-based weigh-in-motion systems.

DOT National Transportation Integrated Search

2009-12-01

Monitoring truck weights is essential for traffic operations, roadway design, traffic safety, and regulations. : Traditional roadside static truck weighing stations have many operational shortcomings, and so there have : been ongoing efforts to devel...

Maritime trade & transportation 2007

DOT National Transportation Integrated Search

2005-01-10

This latest edition of Maritime Trade and Transportation follows two prior reports released in 1999 and 2002. These reports refl ect an ongoing effort by the Maritime Data Working Group to provide quality, timely, comprehensive, and relevant maritime...

Continued improvements at one C3RS site

DOT National Transportation Integrated Search

2015-06-01

Human-factors-based solutions, along with process and technology innovations, can make significant contributions to improving safety in the railroad industry. As part of ongoing efforts to address human-factors, FRA implemented the Confidential Close...

PFCA Article Testing

EPA Science Inventory

The U.S. Environmental Protection Agency (EPA) has established an ongoing effort to quantify possible changes in levels of perfluorinated chemicals (PFCs) in articles of commerce (AOCs). Temporal trends in the concentrations of selected PFCs, including perfluorooctanoic acid (PFO...

United States Army Medical Materiel Development Activity - 1989

DTIC Science & Technology

1990-01-31

physicians to treat diseases such as Korean Hemorrhagic Fever and Lassa Fever. * J-5 Human Monoclonal Antibody is secreted by cultured hybridomas that were...volunteer studies involving a collaborative effort between WRAIR and the Swiss Serum and Vaccine Institute (SSVI). s Lassa Fever Immune Plasma is an...immune globulin used to treat Lassa fever infections. The collection of human immune plasma in Africa is an ongoing contract effort. USANRIID performs

On solid ground. Revenue gains continue to outpace growth in expenses, allowing U.S. hospitals to enjoy record profit and margin.

PubMed

Evans, Melanie

2007-10-29

Hospitals enjoyed a surge in profits last year, reporting an aggregate profit margin of 6%. Executives at financially strong systems credit long-term efforts to improve performance for the results. Elizabeth Concordia, left, of the University of Pittsburgh Medical Center system, says its efforts stressed ongoing consolidation and integration to wipe out waste and errors.

KENNEDY SPACE CENTER, FLA. - In the RLV Hangar, Adm. Harold Gehman, chairman of the Columbia Investigation Accident Board, points to data on a chart. He and other board members are visiting as part of the ongoing investigation. Recovery efforts as of May 5 included 82,500 pieces of debris weighing 84,800 pounds, almost 40 percent of the total dry weight of the shuttle. About 25,000 personnel took part, utilizing almost 1.5 million total man-hours in the recovery effort and involving more than 130 federal, state and local agencies. The operation was also supported by more than 270 organizations that included businesses and volunteer groups.

NASA Image and Video Library

2003-05-15

KENNEDY SPACE CENTER, FLA. - In the RLV Hangar, Adm. Harold Gehman, chairman of the Columbia Investigation Accident Board, points to data on a chart. He and other board members are visiting as part of the ongoing investigation. Recovery efforts as of May 5 included 82,500 pieces of debris weighing 84,800 pounds, almost 40 percent of the total dry weight of the shuttle. About 25,000 personnel took part, utilizing almost 1.5 million total man-hours in the recovery effort and involving more than 130 federal, state and local agencies. The operation was also supported by more than 270 organizations that included businesses and volunteer groups.

KENNEDY SPACE CENTER, FLA. - Adm. Harold Gehman, far left, chairman of the Columbia Investigation Accident Board, looks at pieces of Columbia debris collected in the KSC RLV Hangar. Other members of the board accompanied him as part of the ongoing investigation. Recovery efforts as of May 5 included 82,500 pieces of debris weighing 84,800 pounds, almost 40 percent of the total dry weight of the shuttle. About 25,000 personnel took part, utilizing almost 1.5 million total man-hours in the recovery effort and involving more than 130 federal, state and local agencies. The operation was also supported by more than 270 organizations that included businesses and volunteer groups.

NASA Image and Video Library

2003-05-15

KENNEDY SPACE CENTER, FLA. - Adm. Harold Gehman, far left, chairman of the Columbia Investigation Accident Board, looks at pieces of Columbia debris collected in the KSC RLV Hangar. Other members of the board accompanied him as part of the ongoing investigation. Recovery efforts as of May 5 included 82,500 pieces of debris weighing 84,800 pounds, almost 40 percent of the total dry weight of the shuttle. About 25,000 personnel took part, utilizing almost 1.5 million total man-hours in the recovery effort and involving more than 130 federal, state and local agencies. The operation was also supported by more than 270 organizations that included businesses and volunteer groups.

An economic toolkit for identifying the cost of emergency medical services (EMS) systems: detailed methodology of the EMS Cost Analysis Project (EMSCAP).

PubMed

Lerner, E Brooke; Garrison, Herbert G; Nichol, Graham; Maio, Ronald F; Lookman, Hunaid A; Sheahan, William D; Franz, Timothy R; Austad, James D; Ginster, Aaron M; Spaite, Daniel W

2012-02-01

Calculating the cost of an emergency medical services (EMS) system using a standardized method is important for determining the value of EMS. This article describes the development of a methodology for calculating the cost of an EMS system to its community. This includes a tool for calculating the cost of EMS (the "cost workbook") and detailed directions for determining cost (the "cost guide"). The 12-step process that was developed is consistent with current theories of health economics, applicable to prehospital care, flexible enough to be used in varying sizes and types of EMS systems, and comprehensive enough to provide meaningful conclusions. It was developed by an expert panel (the EMS Cost Analysis Project [EMSCAP] investigator team) in an iterative process that included pilot testing the process in three diverse communities. The iterative process allowed ongoing modification of the toolkit during the development phase, based upon direct, practical, ongoing interaction with the EMS systems that were using the toolkit. The resulting methodology estimates EMS system costs within a user-defined community, allowing either the number of patients treated or the estimated number of lives saved by EMS to be assessed in light of the cost of those efforts. Much controversy exists about the cost of EMS and whether the resources spent for this purpose are justified. However, the existence of a validated toolkit that provides a standardized process will allow meaningful assessments and comparisons to be made and will supply objective information to inform EMS and community officials who are tasked with determining the utilization of scarce societal resources. © 2012 by the Society for Academic Emergency Medicine.

The Architecture and Application of RAMSES, a CCSDS and ECSS PUS Compliant Test and Control System

NASA Astrophysics Data System (ADS)

Battelino, Milan; Svard, Christian; Carlsson, Anna; Carlstedt-Duke, Theresa; Tornqvist, Marcus

2010-08-01

SSC, Swedish Space Corporation, has more than 30 years of experience in developing test and control systems for sounding rockets, experimental test modules and satellites. The increasing amount of ongoing projects made SSC to consider developing a test and control system conformant to CCSDS (Consultative Committee for Space Data Systems) and ECSS (European Cooperation for Space Standardization), that with small effort and cost, could be reused between separate projects and products. The foreseen reduction in cost and development time for different future space-related projects made such a reusable control system desirable. This paper will describe the ideas behind the RAMSES (Rocket and Multi-Satellite EMCS Software) system, its architecture and how it has been and is being used in a variety of applications at SSC such as the multi-satellite mission PRISMA and sounding rocket project MAXUS-8.

The ASP Sensor Network: Infrastructure for the Next Generation of NASA Airborne Science

NASA Astrophysics Data System (ADS)

Myers, J. S.; Sorenson, C. E.; Van Gilst, D. P.; Duley, A.

2012-12-01

A state-of-the-art real-time data communications network is being implemented across the NASA Airborne Science Program core platforms. Utilizing onboard Ethernet networks and satellite communications systems, it is intended to maximize the science return from both single-platform missions and complex multi-aircraft Earth science campaigns. It also provides an open platform for data visualization and synthesis software tools, for use by the science instrument community. This paper will describe the prototype implementations currently deployed on the NASA DC-8 and Global Hawk aircraft, and the ongoing effort to expand the capability to other science platforms. Emphasis will be on the basic network architecture, the enabling hardware, and new standardized instrument interfaces. The new Mission Tools Suite, which provides an web-based user interface, will be also described; together with several example use-cases of this evolving technology.

Childhood growth and chronic disease: evidence from countries undergoing the nutrition transition.

PubMed

Stein, Aryeh D; Thompson, Angela M; Waters, Ashley

2005-07-01

Evidence is accumulating that the pattern of growth in childhood is associated with development of cardiovascular disease in adulthood, but such evidence comes mostly from developed countries. We conducted a review of studies from countries undergoing the nutrition transition. Five birth cohorts with measures of child growth and outcomes through adolescence were identified, from China, India, Guatemala, Brazil and the Philippines. Across studies there are major differences in data availability and in statistical approaches to modelling child growth and its effects. Nevertheless, generally consistent associations of growth failure in early childhood and development of overweight in later childhood with the risk of elevated blood pressure, glucose, and serum lipids in adulthood were observed. As these cohorts mature they will provide a wealth of critical information on the relation between early life factors and later disease risk, and efforts should be made to ensure ongoing follow-up using standardized approaches and more comprehensive assessments.

Recent Advances in Targeted Therapy for Glioma.

PubMed

Lin, Lin; Cai, Jinquan; Jiang, Chuanlu

2017-01-01

Gliomas are the most common primary malignant brain tumors, which have a universally fatal outcome. Current standard treatment for glioma patients is surgical removal followed by radiotherapy and adjuvant chemotherapy. Due to therapeutic resistance and tumor recurrence, efforts are ongoing to identify the molecules that are fundamental to regulate the tumor progression and provide additional methods for individual treatment of glioma patients. By studying the initiation and maintenance of glioma, studies focused on the targets of tyrosine kinase receptors including EGFR, PDGFR and other crucial signal pathways such as PI3K/AKT and RAS/RAF/MAPK pathway. Furthermore, recent advances in targeting immunotherapy and stem cell therapy also brought numerous strategies to glioma treatment. This article reviewed the researches focused on the advanced strategies of various target therapies for improving the glioma treatment efficacy, and discussed the challenges and future directions for glioma therapy. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

PROOF OF CONCEPT FOR A HUMAN RELIABILITY ANALYSIS METHOD FOR HEURISTIC USABILITY EVALUATION OF SOFTWARE

DOE Office of Scientific and Technical Information (OSTI.GOV)

Ronald L. Boring; David I. Gertman; Jeffrey C. Joe

2005-09-01

An ongoing issue within human-computer interaction (HCI) is the need for simplified or “discount” methods. The current economic slowdown has necessitated innovative methods that are results driven and cost effective. The myriad methods of design and usability are currently being cost-justified, and new techniques are actively being explored that meet current budgets and needs. Recent efforts in human reliability analysis (HRA) are highlighted by the ten-year development of the Standardized Plant Analysis Risk HRA (SPAR-H) method. The SPAR-H method has been used primarily for determining humancentered risk at nuclear power plants. The SPAR-H method, however, shares task analysis underpinnings withmore » HCI. Despite this methodological overlap, there is currently no HRA approach deployed in heuristic usability evaluation. This paper presents an extension of the existing SPAR-H method to be used as part of heuristic usability evaluation in HCI.« less

Assessment of Severe Apnoea through Voice Analysis, Automatic Speech, and Speaker Recognition Techniques

NASA Astrophysics Data System (ADS)

Fernández Pozo, Rubén; Blanco Murillo, Jose Luis; Hernández Gómez, Luis; López Gonzalo, Eduardo; Alcázar Ramírez, José; Toledano, Doroteo T.

2009-12-01

This study is part of an ongoing collaborative effort between the medical and the signal processing communities to promote research on applying standard Automatic Speech Recognition (ASR) techniques for the automatic diagnosis of patients with severe obstructive sleep apnoea (OSA). Early detection of severe apnoea cases is important so that patients can receive early treatment. Effective ASR-based detection could dramatically cut medical testing time. Working with a carefully designed speech database of healthy and apnoea subjects, we describe an acoustic search for distinctive apnoea voice characteristics. We also study abnormal nasalization in OSA patients by modelling vowels in nasal and nonnasal phonetic contexts using Gaussian Mixture Model (GMM) pattern recognition on speech spectra. Finally, we present experimental findings regarding the discriminative power of GMMs applied to severe apnoea detection. We have achieved an 81% correct classification rate, which is very promising and underpins the interest in this line of inquiry.

Monitoring water quality in Toronto's urban stormwater ponds: Assessing participation rates and data quality of water sampling by citizen scientists in the FreshWater Watch.

PubMed

Scott, Andrew B; Frost, Paul C

2017-08-15

From 2013 to 2015, citizen scientist volunteers in Toronto, Canada were trained to collect and analyze water quality in urban stormwater ponds. This volunteer sampling was part of the research program, FreshWater Watch (FWW), which aimed to standardize urban water sampling efforts from around the globe. We held training sessions for new volunteers twice yearly and trained a total of 111 volunteers. Over the course of project, ~30% of volunteers participated by collecting water quality data after the training session with 124 individual sampling events at 29 unique locations in Toronto, Canada. A few highly engaged volunteers were most active, with 50% of the samples collected by 5% of trainees. Stormwater ponds generally have poor water quality demonstrated by elevated phosphate concentrations (~30μg/L), nitrate (~427μg/L), and turbidity relative to Canadian water quality standards. Compared to other urban waterbodies in the global program, nutrient concentrations in Toronto's urban stormwater ponds were lower, while turbidity was not markedly different. Toronto FWW (FWW-TO) data was comparable to that measured by standard lab analyses and matched results from previous studies of stormwater ponds in Toronto. Combining observational and chemical data acquired by citizen scientists, macrophyte dominated ponds had lower phosphate concentrations while phytoplankton dominated ponds had lower nitrate concentrations, which indicates a potentially important and unstudied role of internal biogeochemical processes on pond nutrient dynamics. This experience in the FWW demonstrates the capabilities and constraints of citizen science when applied to water quality sampling. While analytical limits on in-field analyses produce higher uncertainty in water quality measurements of individual sites, rapid data collection is possible but depends on the motivation and engagement of the group of volunteers. Ongoing efforts in citizen science will thus need to address sampling effort and analytical limits to fully realize the potential value of engaging citizen scientists in water quality sampling. Copyright © 2017 Elsevier B.V. All rights reserved.

An Overview of the Launch Vehicle Blast Environments Development Efforts

NASA Technical Reports Server (NTRS)

Richardson, Erin; Bangham, Mike; Blackwood, James; Skinner, Troy; Hays, Michael; Jackson, Austin; Richman, Ben

2014-01-01

NASA has been funding an ongoing development program to characterize the explosive environments produced during a catastrophic launch vehicle accident. These studies and small-scale tests are focused on the near field environments that threaten the crew. The results indicate that these environments are unlikely to result in immediate destruction of the crew modules. The effort began as an independent assessment by NASA safety organizations, followed by the Ares program and NASA Engineering and Safety Center and now as a Space Launch Systems (SLS) focused effort. The development effort is using the test and accident data available from public or NASA sources as well as focused scaled tests that are examining the fundamental aspects of uncontained explosions of Hydrogen and air and Hydrogen and Oxygen. The primary risk to the crew appears to be the high-energy fragments and these are being characterized for the SLS. The development efforts will characterize the thermal environment of the explosions as well to ensure that the risk is well understood and to document the overall energy balance of an explosion. The effort is multi-path in that analytical, computational and focused testing is being used to develop the knowledge to understand potential SLS explosions. This is an ongoing program with plans that expand the development from fundamental testing at small-scale levels to large-scale tests that can be used to validate models for commercial programs. The ultimate goal is to develop a knowledge base that can be used by vehicle designers to maximize crew survival in an explosion.

77 FR 66609 - Notice of FERC Staff Attendance

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-06

... El Paso Electric Company ER13-91-000 Black Hills Power, Inc., et al......... ER13-96-000 Black Hills... ongoing outreach efforts. The meeting may discuss matters at issue in the above captioned dockets. For...

78 FR 16497 - Notice of FERC Staff Attendance

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-15

... Electric Company ER13-91-000 Black Hills Power, Inc., et al ER13-96-000 Black Hills Colorado Electric... of the Commission's ongoing outreach efforts. The meeting may discuss matters at issue in the above...

77 FR 74844 - Notice of FERC Staff Attendance

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-18

............ Docket No. ER13-91-000. Black Hills Power, Inc., et al... Docket No. ER13-96-000. Black Hills Colorado... Commission's ongoing outreach efforts. The meeting may discuss matters at issue in the above captioned...

Climate change : observations on federal efforts to adapt to a changing climate

DOT National Transportation Integrated Search

2009-03-25

Based on preliminary observations from GAOs ongoing adaptation work for the Select Committee on Energy Independence and Global Warming, certain federal, state, local, and international government authorities are beginning to consider and implement...

EPA Office of Research and Development Green Infrastructure Research

EPA Science Inventory

This presentation provides an overview introduction to the USEPA Office of Research and Development (ORD)'s ongoing green infrastructure (GI) research efforts for stormwater management. GI approaches that increase infiltration, evapotranspiration, and rainwater harvesting offer ...

Mouse Sperm Cryopreservation Using Cryoprotectant Containing l-Glutamine.

PubMed

Takeo, Toru; Nakagata, Naomi

2018-06-01

Efforts to advance sperm cryopreservation are ongoing and include modifications in the cryoprotective agents. The addition of l-glutamine maintains post-thaw motility and reduces plasma membrane damage to sperm. © 2018 Cold Spring Harbor Laboratory Press.

Community Update on Site Activities, July 19, 2013

EPA Pesticide Factsheets

In an effort to engage and inform community members interested in the New Bedford Harbor Superfund Site cleanup, EPA will be issuing periodic topic-based fact sheets that will provide background information and updates about ongoing activities.

Drugs and highway safety 1980

DOT National Transportation Integrated Search

1980-05-01

This report presents findings of a study to describe (1) present knowledge about the relationship between drug use by drivers and highway safety, and (2) efforts to detect and prevent drug-impaired driving. Past, ongoing, and planned activities at fe...

Scientific Basis for Biotech Crops

EPA Science Inventory

Efforts to change the genetic makeup of plants have been ongoing since the beginning of agriculture, thousands of years ago. Early plant improvements relied on simply cross-breeding cultivars with desired traits. Advancements in mutation breeding through chemicals and radiation ...

Alternative methods for developing external travel survey data.

DOT National Transportation Integrated Search

2010-10-01

The Texas Department of Transportation (TxDOT) has a comprehensive on-going travel survey : program that supports the travel demand models being developed for transportation planning efforts in urban : areas throughout Texas. One component of the sur...

DOT's Restructuring - Limited Progress in Streamlining Field Office Structure

DOT National Transportation Integrated Search

1998-04-30

The report characterizes two ongoing efforts in the Department involving our : analysis of opportunities to collocate field offices on an intermodal basis, and : FHWA's examination of its regional office structure. Although many aspects of : our effo...

78 FR 2445 - Notice of Intent To Renew the Advisory Committee on Apprenticeship (ACA) Charter

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-11

... and partners for its ongoing operational effectiveness. Apart from the ACA, there is no single..., veterans, women, minorities and other under-utilized and disadvantaged populations; and (5) efforts to...

Placebo effect in clinical trial design for irritable bowel syndrome.

PubMed

Shah, Eric; Pimentel, Mark

2014-04-30

Ongoing efforts to improve clinical trial design in irritable bowel syndrome have been hindered by high placebo response rates and ineffective outcome measures. We assessed established strategies to minimize placebo effect as well as the various ap-proaches to placebo effect which can affect trial design. These include genetic markers such as catechol-O-methyltransferase, opioidergic and dopaminergic neurobiologic theory, pre-cebo effect centered on expectancy theory, and side effect unblinding grounded on conditioning theory. We reviewed endpoints used in the study of IBS over the past decade including adequate relief and subjective global relief, emphasizing their weaknesses in fully evaluating the IBS condition, specifically their motility effects based on functional net value and relative benefit-harm based on dropouts due to adverse events. The focus of this review is to highlight ongoing efforts to improve clinical trial design which can lead to better outcomes in a real-world setting.

Increasing Racial/Ethnic Diversity in Nursing to Reduce Health Disparities and Achieve Health Equity

PubMed Central

Malone, Beverly

2014-01-01

As nursing continues to advance health care in the 21st century, the current shift in demographics, coupled with the ongoing disparities in health care and health outcomes, will warrant our ongoing attention and action. As within all health professions, concerted efforts are needed to diversify the nation's health-care workforce. The nursing profession in particular will be challenged to recruit and retain a culturally diverse workforce that mirrors the nation's change in demographics. This increased need to enhance diversity in nursing is not new to the profession; however, the need to successfully address this issue has never been greater. This article discusses increasing the diversity in nursing and its importance in reducing health disparities. We highlight characteristics of successful recruitment and retention efforts targeting racial/ethnic minority nurses and conclude with recommendations to strengthen the development and evaluation of their contributions to eliminating health disparities. PMID:24385664

24 CFR 35.1355 - Ongoing lead-based paint maintenance and reevaluation activities.

Code of Federal Regulations, 2012 CFR

2012-04-01

... Secretary, Department of Housing and Urban Development LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Methods and Standards for Lead-Paint Hazard Evaluation and Hazard Reduction Activities... 24 Housing and Urban Development 1 2012-04-01 2012-04-01 false Ongoing lead-based paint...

24 CFR 35.1355 - Ongoing lead-based paint maintenance and reevaluation activities.

Code of Federal Regulations, 2013 CFR

2013-04-01

... Secretary, Department of Housing and Urban Development LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Methods and Standards for Lead-Paint Hazard Evaluation and Hazard Reduction Activities... 24 Housing and Urban Development 1 2013-04-01 2013-04-01 false Ongoing lead-based paint...

24 CFR 35.1355 - Ongoing lead-based paint maintenance and reevaluation activities.

Code of Federal Regulations, 2011 CFR

2011-04-01

... Secretary, Department of Housing and Urban Development LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Methods and Standards for Lead-Paint Hazard Evaluation and Hazard Reduction Activities... 24 Housing and Urban Development 1 2011-04-01 2011-04-01 false Ongoing lead-based paint...

24 CFR 35.1355 - Ongoing lead-based paint maintenance and reevaluation activities.

Code of Federal Regulations, 2014 CFR

2014-04-01

... Secretary, Department of Housing and Urban Development LEAD-BASED PAINT POISONING PREVENTION IN CERTAIN RESIDENTIAL STRUCTURES Methods and Standards for Lead-Paint Hazard Evaluation and Hazard Reduction Activities... 24 Housing and Urban Development 1 2014-04-01 2014-04-01 false Ongoing lead-based paint...

Coast Guard: Efforts to Identify Arctic Requirements Are Ongoing, but More Communication about Agency Planning Efforts Would Be Beneficial

DTIC Science & Technology

2010-09-01

involve Indian tribal governments, such as certain Arctic indigenous communities in Alaska , in decisions that affect them.14 Finally, since the Arctic...primarily as vehicles for distributing land and monetary benefits to Alaska Natives to provide a fair and just settlement of aboriginal land claims in... Alaska Native stakeholders, as well as private or nonprofit organizations representing Arctic interests. These observations are not

Waldenstrom Macroglobulinemia☆

PubMed Central

Leleu, Xavier; Roccaro, Aldo M.; Moreau, Anne-Sophie; Dupire, Sophie; Robu, Daniela; Gay, Julie; Hatjiharissi, Evdoxia; Burwik, Nicholas; Ghobrial, Irene M.

2011-01-01

In the past years, new developments have occurred both in the understanding of the biology of Waldenstrom Macroglobulinemia (WM) and in therapeutic options for WM. WM is a B-cell disorder characterized primarily by bone marrow infiltration with lymphoplasmacytic cells, along with demonstration of an IgM monoclonal gammopathy. Despite advances in therapy, WM remains incurable, with 5–6 years median overall survival of patients in symptomatic WM. Therapy is postponed for asymptomatic patients, and progressive anemia is the most common indication for initiation of treatment. The main therapeutic options include alkylating agents, nucleoside analogues, and rituximab. Studies involving combination chemotherapy are ongoing, and preliminary results are encouraging. No specific agent or regimen has been shown to be superior to another for treatment of WM. As such, novel therapeutic agents are needed for the treatment of WM. In ongoing efforts, we and others have sought to exploit advances made in the understanding of the biology of WM so as to better target therapeutics for this malignancy. These efforts have led to the development of several novel agents including the proteasome inhibitor bortezomib, and several Akt/mTor inhibitors, perifosine and Rad001, and immunomodulatory agents such as thalidomide and lenalidomide. Studies with monoclonal antibodies are ongoing and promising including the use of alemtuzumab, SGN-70, and the APRIL/BLYS blocking protein TACI-Ig atacicept. Other agents currently being tested in clinical trials include the PKC inhibitor enzastaurin, the natural product resveratrol, as well as the statin simvastatin. This report provides an update of the current preclinical studies and clinical efforts for the development of novel agents in the treatment of WM. PMID:18555588

Final report, on-going key comparison BIPM.QM-K1, ozone at ambient level, comparison with CMS-ITRI, June 2016

NASA Astrophysics Data System (ADS)

Viallon, Joële; Idrees, Faraz; Moussay, Philippe; Wielgosz, Robert; Lin, Tsai-Yin; Norris, James E.; Hodges, Joseph T.

2017-01-01

As part of the on-going key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of the ITRI Center for Measurement Standards (CMS-ITRI) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM), via a transfer standard maintained by the National Institute of Standards and Technology (NIST). The instruments have been compared over a nominal ozone amount-of-substance fraction range of 0 nmol/mol to 500 nmol/mol. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Risk of bias and confounding of observational studies of Zika virus infection: A scoping review of research protocols

PubMed Central

Haby, Michelle M.; Martínez-Vega, Ruth; Pinzón-Flores, Carlos E.; Smith, Emma; Pinart, Mariona; Broutet, Nathalie; Becerra-Posada, Francisco; Aldighieri, Sylvain; Van Kerkhove, Maria D.

2017-01-01

Introduction Given the severity and impact of the current Zika virus (ZIKV) outbreak in the Americas, numerous countries have rushed to develop research studies to assess ZIKV and its potential health consequences. In an effort to ensure that studies are comprehensive, both internally and externally valid, and with reliable results, the World Health Organization, the Pan American Health Organization, Institut Pasteur, the networks of Fiocruz, the Consortia for the Standardization of Influenza Seroepidemiology (CONSISE) and the International Severe Acute Respiratory and Emerging Infection Consortium (ISARIC) have generated six standardized clinical and epidemiological research protocols and questionnaires to address key public health questions on ZIKV. Methods We conducted a systematic search of ongoing study protocols related to ZIKV research. We analyzed the content of protocols of 32 cohort studies and 13 case control studies for systematic bias that could produce erroneous results. Additionally we aimed to characterize the risks of bias and confounding in observational studies related to ZIKV and to propose ways to minimize them, including the use of six newly standardized research protocols. Results Observational studies of ZIKV face an array of challenges, including measurement of exposure and outcomes (microcephaly and Guillain-Barré Syndrome). Potential confounders need to be measured where known and controlled for in the analysis. Selection bias due to non-random selection is a significant issue, particularly in the case-control design, and losses to follow-up is equally important for the cohort design. Conclusion Observational research seeking to answer key questions on the ZIKV should consider these restrictions and take precautions to minimize bias in an effort to provide reliable and valid results. Utilization of the standardized research protocols developed by the WHO, PAHO, Institut Pasteur, and CONSISE will harmonize the key methodological aspects of each study design to minimize bias at different stages of the study. Biases need to be considered by researchers implementing the standardized protocols as well as by users of observational epidemiological studies of ZIKV. PMID:28686621

Targeting oncogenic vulnerabilities in triple negative breast cancer: biological bases and ongoing clinical studies

PubMed Central

Ocana, Alberto; Pandiella, Atanasio

2017-01-01

Triple negative breast cancer (TNBC) is still an incurable disease despite the great scientific effort performed during the last years. The huge heterogeneity of this disease has motivated the evaluation of a great number of therapies against different molecular alterations. In this article, we review the biological bases of this entity and how the known molecular evidence supports the current preclinical and clinical development of new therapies. Special attention will be given to ongoing clinical studies and potential options for future drug combinations. PMID:28108739

Advances in HIV-1 Vaccine Development

PubMed Central

Gao, Yong

2018-01-01

An efficacious HIV-1 vaccine is regarded as the best way to halt the ongoing HIV-1 epidemic. However, despite significant efforts to develop a safe and effective vaccine, the modestly protective RV144 trial remains the only efficacy trial to provide some level of protection against HIV-1 acquisition. This review will outline the history of HIV vaccine development, novel technologies being applied to HIV vaccinology and immunogen design, as well as the studies that are ongoing to advance our understanding of vaccine-induced immune correlates of protection. PMID:29614779

Snow removal performance metrics : final report.

DOT National Transportation Integrated Search

2017-05-01

This document is the final report for the Clear Roads project entitled Snow Removal Performance Metrics. The project team was led by researchers at Washington State University on behalf of Clear Roads, an ongoing pooled fund research effort focused o...

Determination of Perfluorinated Compounds in the Upper Mississippi River Basin

EPA Science Inventory

Despite ongoing efforts to develop robust analytical methods for the determination of perfluorinated compounds (PFCs) such as perfluorooctanesulfonate (PFOS) and perfluorooctanoic acid (PFOA) in surface water, comparatively little has been published on method performance, and the...

NREL Leads Effort to Get Traffic Moving in the Right Direction | News |

Science.gov Websites

fuels. This emerging approach to sustainable transportation augments ongoing work by NREL that is aimed at taking a systems approach to the broader network of travelers, services, and environments in order

Trophic Pathways of the Mid-North Atlantic

EPA Science Inventory

Because deep-sea fisheries are increasing as coastal fisheries decline, fisheries scientists need baseline data on deep-sea ecosystems prior to further development of deep-water fisheries. We present preliminary results and ongoing efforts to characterize the trophic structure a...

Gearing up to handle the mosaic nature of life in the quest for orthologs.

PubMed

Forslund, Kristoffer; Pereira, Cecile; Capella-Gutierrez, Salvador; Sousa da Silva, Alan; Altenhoff, Adrian; Huerta-Cepas, Jaime; Muffato, Matthieu; Patricio, Mateus; Vandepoele, Klaas; Ebersberger, Ingo; Blake, Judith; Fernández Breis, Jesualdo Tomás; Boeckmann, Brigitte; Gabaldón, Toni; Sonnhammer, Erik; Dessimoz, Christophe; Lewis, Suzanna

2017-08-30

The Quest for Orthologs (QfO) is an open collaboration framework for experts in comparative phylogenomics and related research areas who have an interest in highly accurate orthology predictions and their applications. We here report highlights and discussion points from the QfO meeting 2015 held in Barcelona. Achievements in recent years have established a basis to support developments for improved orthology prediction and to explore new approaches. Central to the QfO effort is proper benchmarking of methods and services, as well as design of standardized datasets and standardized formats to allow sharing and comparison of results. Simultaneously, analysis pipelines have been improved, evaluated, and adapted to handle large datasets. All this would not have occurred without the long-term collaboration of Consortium members. Meeting regularly to review and coordinate complementary activities from a broad spectrum of innovative researchers clearly benefits the community. Highlights of the meeting include addressing sources of and legitimacy of disagreements between orthology calls, the context dependency of orthology definitions, special challenges encountered when analyzing very anciently rooted orthologies, orthology in the light of whole-genome duplications, and the concept of orthologous versus paralogous relationships at different levels, including domain-level orthology. Furthermore, particular needs for different applications (e.g. plant genomics, ancient gene families, and others) and the infrastructure for making orthology inferences available (e.g. interfaces with model organism databases) were discussed, with several ongoing efforts that are expected to be reported on during the upcoming 2017 QfO meeting. © The Author(s) 2017. Published by Oxford University Press.

Using sunshine for elementary space science education: A model for IHY scientist teacher partnerships

NASA Astrophysics Data System (ADS)

Moldwin, M. B.; Fiello, D.; Harter, E.; Holman, G.; Nagumo, N.; Pryharski, A.; Takunaga, C.

2008-12-01

An elementary science education professional development partnership between Culver City Unified School District teachers and UCLA has been formed. The project was designed to assist teachers to comfortably present introductory space science concepts, to support them in their efforts, and to aid them in encouraging their students to develop inquiry skills related to space sciences. The project encourages teacher use of observational science techniques in their classrooms, the use of NASA solar mission images and enhanced use of astronomical observation to facilitate discovery learning. The integrated approach of the project has fostered collegial learning activities among the participating teachers and offered them opportunities for continued renewal and professional development of teacher competencies in astronomy and space science. The activities used in the classroom were developed by others, classroom tested, and specifically address National Science Education and California Science Content Standards. These activities have been sustained through on-going collaboration between the scientist and the teachers, a summer Research Experience for Teachers program, and on-going, grade-specific, district-sponsored workshops. Assessment of the value of the program is done by the school district and is used to continuously improve each workshop and program component. Culver City (California) Unified School District is a small urban school district located on the Westside of Los Angeles. This paper describes the program and the plans for incorporating IHY-themed science into the classroom.

36 CFR Appendix A to Part 1234 - Minimum Security Standards for Level III Federal Facilities

Code of Federal Regulations, 2014 CFR

2014-07-01

... technology and blast standards. Immediate review of ongoing projects may generate savings in the... critical systems (alarm systems, radio communications, computer facilities, etc.) Required. Occupant... all exterior windows (shatter protection) Recommended. Review current projects for blast standards...

36 CFR Appendix A to Part 1234 - Minimum Security Standards for Level III Federal Facilities

Code of Federal Regulations, 2012 CFR

2012-07-01

... technology and blast standards. Immediate review of ongoing projects may generate savings in the... critical systems (alarm systems, radio communications, computer facilities, etc.) Required. Occupant... all exterior windows (shatter protection) Recommended. Review current projects for blast standards...

75 FR 64778 - Request for Comments on Negotiating Objectives With Respect to Malaysia's Participation in the...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-20

... negotiating objectives with respect to Malaysia's participation in the ongoing negotiations of a Trans-Pacific... commence negotiations with Malaysia as part of the ongoing negotiations of a TPP trade agreement. Including Malaysia in the TPP negotiations furthers the objective of achieving a high-standard, broad-based Asia...

A neuroscience perspective on sexual risk behavior in adolescence and emerging adulthood

PubMed Central

VICTOR, ELIZABETH C.; HARIRI, AHMAD R.

2016-01-01

Late adolescence and emerging adulthood (specifically ages 15–24) represent a period of heightened sexual risk taking resulting in the greatest annual rates of sexually transmitted infections and unplanned pregnancies in the US population. Ongoing efforts to prevent such negative consequences are likely to benefit from a deepening of our understanding of biological mechanisms through which sexual risk taking emerges and biases decision making during this critical window. Here we present a neuroscience framework from which a mechanistic examination of sexual risk taking can be advanced. Specifically, we adapt the neurodevelopmental triadic model, which outlines how motivated behavior is governed by three systems: approach, avoidance, and regulation, to sexual decision making and subsequent risk behavior. We further propose a testable hypothesis of the triadic model, wherein relatively decreased threat-related amygdala reactivity and increased reward-related ventral striatum reactivity leads to sexual risk taking, which is particularly exaggerated during adolescence and young adulthood when there is an overexpression of dopaminergic neurons coupled with immature top-down prefrontal cortex regulation. We conclude by discussing how future research based on our adapted triadic model can inform ongoing efforts to improve intervention and prevention efforts. PMID:26611719

A review of HIV/AIDS system-level interventions

PubMed Central

Bauermeister, José A.; Tross, Susan; Ehrhardt, Anke A.

2010-01-01

The escalating HIV/AIDS epidemic worldwide demands that on-going prevention efforts be strengthened, disseminated, and scaled-up. System-level interventions refer to programs aiming to improve the functioning of an agency as well as the delivery of its services to the community. System-level interventions are a promising approach to HIV/AIDS prevention because they focus on (a) improving the agency’s ability to adopt evidence-based HIV prevention and care programs; (b) develop and establish policies and procedures that maximize the sustainability of on-going prevention and care efforts; and (c) improve decision-making processes such as incorporating the needs of communities into their tailored services. We reviewed studies focusing on system-level interventions by searching multiple electronic abstracting indices, including PsycInfo, PubMed, and ProQuest. Twenty-three studies out of 624 peer-reviewed studies (published from January 1985 to February 2007) met study criteria. Most of the studies focused on strengthening agency infrastructure, while other studies included collaborative partnerships and technical assistance programs. Our findings suggest that system-level interventions are promising in strengthening HIV/AIDS prevention and treatment efforts. Based on our findings, we propose recommendations for future work in developing and evaluating system-level interventions. PMID:18369722

[TOPICS-MDS: a versatile resource for generating scientific and social knowledge for elderly care].

PubMed

van den Brink, Danielle; Lutomski, Jennifer E; Qin, Li; den Elzen, Wendy P J; Kempen, Gertrudis I J M; Krabbe, Paul F M; Steyerberg, Ewout W; Muntinga, Maaike; Moll van Charante, Eric P; Bleijenberg, Nienke; Olde Rikkert, Marcel G M; Melis, René J F

2015-04-01

Developed as part of the National Care for the Elderly Programme (NPO), TOPICS-MDS is a uniform, national database on the health and wellbeing of the older persons and caregivers who participated in NPO-funded projects. TOPICS-MDS Consortium has gained extensive experience in constructing a standardized questionnaire to collect relevant health care data on quality of life, health services utilization, and informal care use. A proactive approach has been undertaken not only to ensure the standardization and validation of instruments but also the infrastructure for external data requests. Efforts have been made to promote scientifically and socially responsible use of TOPICS-MDS; data has been available for secondary use since early 2014. Through this data sharing initiative, researchers can explore health issues in a broader framework which may have not been possible within individual NPO projects; this broader framework is highly relevant for influencing health policy. In this article, we provide an overview of the development and on-going progress of TOPICS-MDS. We further describe how information derived from TOPICS-MDS can be applied to facilitate future scientific innovations and public health initiatives to improve care for frail older persons and their caregivers.

New schools design: Acoustics as main target

NASA Astrophysics Data System (ADS)

Maffei, Luigi; Lembo, Paola

2005-04-01

The effects of poor intelligibility and high background noise levels on the cognitive development of school children and on the dissatisfaction of teachers has been largely investigated. National standards have been implemented and attempts to harmonize these standards in international guidelines are ongoing. All these activities have led to the awareness that design of new schools must be centered on the achievement of a good acoustic environment. At this point a strong research effort to study and implement best solutions must be conducted, in collaboration, by architects, acousticians, pedagogues, psychologists, builders and acoustic materials producers. Recently an international competition for the planning of new primary schools in Rome, Italy has been announced. The aim of the competition is to study new architectural and running features of primary schools to obtain, among other parameters such as lighting, low cost energy solutions and air quality, the control of reverberation time, sound insulation and mechanical equipments noise. In these school buildings, as innovative requirement, children must be also able to elaborate interpretative hypothesis of physical phenomena such as sound emission and perception and be aware of their influence on these phenomena. Different possible solutions are presented.

The current format and ongoing advances of medical education in the United States.

PubMed

Gishen, Kriya; Ovadia, Steven; Arzillo, Samantha; Avashia, Yash; Thaller, Seth R

2014-01-01

The objective of this study was to examine the current system of medical education along with the advances that are being made to support the demands of a changing health care system. American medical education must reform to anticipate the future needs of a changing health care system. Since the dramatic transformations to medical education that followed the publication of the Flexner report in 1910, medical education in the United States has largely remained unaltered. Today, the education of future physicians is undergoing modifications at all levels: premedical education, medical school, and residency training. Advances are being made with respect to curriculum design and content, standardized testing, and accreditation milestones. Fields such as plastic surgery are taking strides toward improving resident training as the next accreditation system is established. To promote more efficacious medical education, the American Medical Association has provided grants for innovations in education. Likewise, the Accreditation Council for Graduate Medical Education outlined 6 core competencies to standardize the educational goals of residency training. Such efforts are likely to improve the education of future physicians so that they are able to meet the future needs of American health care.

77 FR 66609 - Notice of FERC Staff Attendance; PacifiCorp, et al.

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-06

...-82-000 El Paso Electric Company ER13-91-000 Black Hills Power, Inc., et al......... ER13-96-000 Black... Commission's ongoing outreach efforts. The meeting may discuss matters at issue in the above captioned...

Guidelines for development of the Iowa statewide transportation improvement program (STIP). Revised.

DOT National Transportation Integrated Search

2004-01-01

The Transportation Equity Act for the 21st Century (TEA-21) continues the Intermodal Surface Transportation Efficiency Act of 1991's requirement for an extensive, ongoing cooperative planning effort for programming federal funding. Iowa's STIP is dev...

Clean Water State Revolving Fund (CWSRF) Environmental Benefits Report

EPA Pesticide Factsheets

This report is a snapshot of the CWSRF’s positive role in improving our nation’s waters to support the goals of the CWA. The report also highlights ongoing CWSRF efforts to improve infrastructure resiliency against extreme weather events.

77 FR 1060 - Proposed Information Collection; Comment Request; Survey of the Need for the Improvement of...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-09

... ). SUPPLEMENTARY INFORMATION: I. Abstract This is a request for a new information collection. The Sensor Science... ongoing effort, and in response to many inquiries and requests in recent years, NIST plans to survey...

Highlights of Transient Plume Impingement Model Validation and Applications

NASA Technical Reports Server (NTRS)

Woronowicz, Michael

2011-01-01

This paper describes highlights of an ongoing validation effort conducted to assess the viability of applying a set of analytic point source transient free molecule equations to model behavior ranging from molecular effusion to rocket plumes. The validation effort includes encouraging comparisons to both steady and transient studies involving experimental data and direct simulation Monte Carlo results. Finally, this model is applied to describe features of two exotic transient scenarios involving NASA Goddard Space Flight Center satellite programs.

Compendium of GAO’s Views on the Cost Saving Proposals of the Grace Commission. Volume 1. Summary of Findings.

DTIC Science & Technology

1985-02-19

effort to develop a govern- ment-wide integrated financial management structure. Such an effort must have a solid base of fundamental concepts to guide ...initiatives address many PPSSCC debt collection concerns The PPSSCC recommendations basically parallel our prior *- recommendations and ongoing OMB...PPSSCC recommended either selling the PMAs’ facilities or adjusting the PMAs’ user fees, ratemaking process, and pricina structure. In total, the PPSSCC

A Critical Examination of the DOD’s Business Management Modernization Program

DTIC Science & Technology

2005-05-01

Program (BMMP) is a key element of the DoD’s ongoing efforts to transform itself. This paper argues that the BMMP needs to be fundamentally reoriented...communication role it plays in the defense- transformation effort. Introduction The core assumption underlying the DoD’s Business Management... government activities. That this is a core assumption for the BMMP is borne out by the fact that the program’s primary objective is to produce

Infusing Software Engineering Technology into Practice at NASA

NASA Technical Reports Server (NTRS)

Pressburger, Thomas; Feather, Martin S.; Hinchey, Michael; Markosia, Lawrence

2006-01-01

We present an ongoing effort of the NASA Software Engineering Initiative to encourage the use of advanced software engineering technology on NASA projects. Technology infusion is in general a difficult process yet this effort seems to have found a modest approach that is successful for some types of technologies. We outline the process and describe the experience of the technology infusions that occurred over a two year period. We also present some lessons from the experiences.

An Investigation of Reliability Models for Ceramic Matrix Composites and their Implementation into Finite Element Codes

NASA Technical Reports Server (NTRS)

Duffy, Stephen F.

1998-01-01

The development of modeling approaches for the failure analysis of ceramic-based material systems used in high temperature environments was the primary objective of this research effort. These materials have the potential to support many key engineering technologies related to the design of aeropropulsion systems. Monolithic ceramics exhibit a number of useful properties such as retention of strength at high temperatures, chemical inertness, and low density. However, the use of monolithic ceramics has been limited by their inherent brittleness and a large variation in strength. This behavior has motivated material scientists to reinforce the monolithic material with a ceramic fiber. The addition of a second ceramic phase with an optimized interface increases toughness and marginally increases strength. The primary purpose of the fiber is to arrest crack growth, not to increase strength. The material systems of interest in this research effort were laminated ceramic matrix composites, as well as two- and three- dimensional fabric reinforced ceramic composites. These emerging composite systems can compete with metals in many demanding applications. However, the ongoing metamorphosis of ceramic composite material systems, and the lack of standardized design data has in the past tended to minimize research efforts related to structural analysis. Many structural components fabricated from ceramic matrix composites (CMC) have been designed by "trial and error." The justification for this approach lies in the fact that during the initial developmental phases for a material system fabrication issues are paramount. Emphasis is placed on demonstrating feasibility rather than fully understanding the processes controlling mechanical behavior. This is understandable during periods of rapid improvements in material properties for any composite system. But to avoid the ad hoc approach, the analytical methods developed under this effort can be used to develop rational structural design protocols.

Standard setting: the crucial issues. A case study of accounting & auditing.

PubMed

Nowakowski, J R

1982-01-01

A study of standard-setting efforts in accounting and auditing is reported. The study reveals four major areas of concern in a professional standard-setting effort: (1) issues related to the rationale for setting standards, (2) issues related to the standard-setting board and its support structure, (3) issues related to the content of standards and rules for generating them, and (4) issues that deal with how standards are put to use. Principles derived from the study of accounting and auditing are provided to illuminate and assess standard-setting efforts in evaluation.

NEON's eddy-covariance: interoperable flux data products, software and services for you, now

NASA Astrophysics Data System (ADS)

Metzger, S.; Desai, A. R.; Durden, D.; Hartmann, J.; Li, J.; Luo, H.; Durden, N. P.; Sachs, T.; Serafimovich, A.; Sturtevant, C.; Xu, K.

2017-12-01

Networks of eddy-covariance (EC) towers such as AmeriFlux, ICOS and NEON are vital for providing the necessary distributed observations to address interactions at the soil-vegetation-atmosphere interface. NEON, close to full operation with 47 tower sites, will represent the largest single-provider EC network globally. Its standardized observation and data processing suite is designed specifically for inter-site comparability and analysis of feedbacks across multiple spatial and temporal scales. Furthermore, NEON coordinates EC with rich contextual observations such as airborne remote sensing and in-situ sampling bouts. In January 2018 NEON enters its operational phase, and EC data products, software and services become fully available to the science community at large. These resources strive to incorporate lessons-learned through collaborations with AmeriFlux, ICOS, LTER and others, to suggest novel systemic solutions, and to synergize ongoing research efforts across science communities. Here, we present an overview of the ongoing product release, alongside efforts to integrate and collaborate with existing infrastructures, networks and communities. Near-real-time heat, water and carbon cycle observations in "basic" and "expanded", self-describing HDF5 formats become accessible from the NEON Data Portal, including an Application Program Interface. Subsequently, they are ingested into the AmeriFlux processing pipeline, together with inclusion in FLUXNET globally harmonized data releases. Software for reproducible, extensible and portable data analysis and science operations management also becomes available. This includes the eddy4R family of R-packages underlying the data product generation, together with the ability to directly participate in open development via GitHub version control and DockerHub image hosting. In addition, templates for science operations management include a web-based field maintenance application and a graphical user interface to simplify problem tracking and resolution along the entire data chain. We hope that this presentation can initiate further collaboration and synergies in challenge areas, and would appreciate input and discussion on continued development.

A Sandbox Environment for the Community Sensor Model Standard

NASA Astrophysics Data System (ADS)

Hare, T. M.; Laura, J. R.; Humpreys, I. R.; Wilson, T. J.; Hahn, M. A.; Shepherd, M. R.; Sides, S. C.

2017-06-01

Here we present ongoing work Astrogeology is undertaking to provide a programming sandbox environment for the Community Sensor Model standard. We define a sandbox as a testing environment that allows programmers to experiment.

DOE Office of Scientific and Technical Information (OSTI.GOV)

Gregory Reaman

The initiative will enable the COG Biopathology Center (Biospecimen Repository), the Molecular Genetics Laboratory and other participating reference laboratories to upload large data sets to the eRDES. The capability streamlines data currency and accuracy allowing the centers to export data from local systems and import the defined data to the eRDES. The process will aid in the best practices which have been defined by the Office of Biorepository and Biospecimen Research (OBBR) and the Group Banking Committee (GBC). The initiative allows for batch import and export, a data validation process and reporting mechanism, and a model for other labs tomore » incorporate. All objectives are complete. The solutions provided and the defined process eliminates dual data entry resulting in data consistency. The audit trail capabilities allow for complete tracking of the data exchange between laboratories and the Statistical Data Center (SDC). The impact is directly on time and efforts. In return, the process will save money and improve the data utilized by the COG. Ongoing efforts include implementing new technologies to further enhance the current solutions and process currently in place. Web Services and Reporting Services are technologies that have become industry standards and will allow for further harmonization with caBIG (cancer Biolnforrnatics Grid). Additional testing and implementation of the model for other laboratories is in process.« less

Promoting advance directives among African Americans: a faith-based model.

PubMed

Bullock, Karen

2006-02-01

Studies show that African Americans are less likely than other ethnic groups to complete advance directives. However, what influences African Americans' decisions to complete or not complete advance directives is unclear. Using a faith-based promotion model, 102 African Americans aged 55 years or older were recruited from local churches and community-based agencies to participate in a pilot study to promote advance care planning. Focus groups were used to collect data on participants' preferences for care, desire to make personal choices, values and attitudes, beliefs about death and dying, and advance directives. A standardized interview was used in the focus groups, and the data were organized and analyzed using NUDIST 4 software (QRS Software, Victoria, Australia). Three fourths of the participants refused to complete advance directives. The following factors influenced the participants' decisions about end-of-life care and completion of an advance directive: spirituality; view of suffering, death, and dying; social support networks; barriers to utilization; and mistrust of the health care system. The dissemination of information apprises individuals of their right to self-determine about their care, but educational efforts may not produce a significant change in behavior toward completion of advance care planning. Thus, ongoing efforts are needed to improve the trust that African Americans have in medical and health care providers.

Overview of Materials Qualification Needs for Metal Additive Manufacturing

NASA Astrophysics Data System (ADS)

Seifi, Mohsen; Salem, Ayman; Beuth, Jack; Harrysson, Ola; Lewandowski, John J.

2016-03-01

This overview highlights some of the key aspects regarding materials qualification needs across the additive manufacturing (AM) spectrum. AM technology has experienced considerable publicity and growth in the past few years with many successful insertions for non-mission-critical applications. However, to meet the full potential that AM has to offer, especially for flight-critical components (e.g., rotating parts, fracture-critical parts, etc.), qualification and certification efforts are necessary. While development of qualification standards will address some of these needs, this overview outlines some of the other key areas that will need to be considered in the qualification path, including various process-, microstructure-, and fracture-modeling activities in addition to integrating these with lifing activities targeting specific components. Ongoing work in the Advanced Manufacturing and Mechanical Reliability Center at Case Western Reserve University is focusing on fracture and fatigue testing to rapidly assess critical mechanical properties of some titanium alloys before and after post-processing, in addition to conducting nondestructive testing/evaluation using micro-computerized tomography at General Electric. Process mapping studies are being conducted at Carnegie Mellon University while large area microstructure characterization and informatics (EBSD and BSE) analyses are being conducted at Materials Resources LLC to enable future integration of these efforts via an Integrated Computational Materials Engineering approach to AM. Possible future pathways for materials qualification are provided.

ADS-33C related handling qualities research performed using the NRC Bell 205 airborne simulator

NASA Technical Reports Server (NTRS)

Morgan, J. Murray; Baillie, Stewart W.

1993-01-01

Over 10 years ago a project was initiated by the U.S. Army AVSCOM to update the military helicopter flying qualities specification MIL-8501-A. While not yet complete, the project reached a major milestone in 1989 with the publication of an Airworthiness Design Standard, ADS-33C. The 8501 update project initially set out to identify critical gaps in the requisite data base and then proceeded to fill them using a variety of directed research studies. The magnitude of the task required that it become an international effort: appropriate research studies were conducted in Germany, the UK and Canada as well as in the USA. Canadian participation was supported by the Department of National Defence (DND) through the Chief of Research and Development. Both ground based and in-flight simulation were used to study the defined areas and the Canadian Bell 205-A1 variable stability helicopter was used extensively as one of the primary research tools available for this effort. This paper reviews the involvement of the Flight Research Laboratory of the National Research Council of Canada in the update project, it describes the various experiments conducted on the Airborne Simulator, it notes significant results obtained and describes ongoing research associated with the project.

Trials advance low-salinity culture of Cobia, Pompano, and other species

USDA-ARS?s Scientific Manuscript database

An ongoing collaborative research effort between scientists of the USDA Agricultural Research Service and aquaculture researchers of the Harbor Branch Oceanographic Institute at Florida Atlantic University to develop technologies for rearing fish in low salinity recirculating aquaculture systems is ...

The silent customers: measuring customer satisfaction in nursing homes.

PubMed

Kleinsorge, I K; Koenig, H F

1991-12-01

Nursing home administrators concerned with customer satisfaction and quality of care need a tool to assess and monitor ongoing satisfaction of nursing home residents and family members. The authors report a preliminary effort to develop such a survey using focus groups.

THE OPEN SOURCING OF EPANET

EPA Science Inventory

A proposal was made at the 2009 EWRI Congress in Kansas City, MO to establish an Open Source Project (OSP) for the widely used EPANET pipe network analysis program. This would be an ongoing collaborative effort among a group of geographically dispersed advisors and developers, wo...

Midwest regional rail system : a transportation network for the 21 century : executive report

DOT National Transportation Integrated Search

2000-02-01

The Midwest Regional Rail Initiative is an ongoing effort to develop an improved and expanded passenger rail system in the Midwest. Since 1996, the Midwest Regional Rail Initiative (MWRRI) advanced from a series of service concepts, including increas...

Workshops and Training | Eliminating Sanitary Sewer ...

EPA Pesticide Factsheets

2017-04-10

EPA New England is working with partners to develop outreach, workshops and tools to assist those working to prevent sewage overflows and improve the management of water/wastewater systems. We have ongoing efforts on CMOM (Capacity, Management, Operation and Maintenance), Asset Management and energy management.

Computer Augmented Video Education.

ERIC Educational Resources Information Center

Sousa, M. B.

1979-01-01

Describes project CAVE (Computer Augmented Video Education), an ongoing effort at the U.S. Naval Academy to present lecture material on videocassette tape, reinforced by drill and practice through an interactive computer system supported by a 12 channel closed circuit television distribution and production facility. (RAO)

Holes: a novel method for promoting vegetation restoration (Macao)

Treesearch

Shao-Lin Peng; Yi-Na Yu; Yu-Ping Hou; Long-Sheng Yu; Bao-Ming Chen

2009-01-01

Restoration Notes have been a distinguishing feature of Ecological Restoration for more than 25 years. This section is geared toward introducing innovative research, tools, technologies, programs, and ideas, as well as providing short-term research results and updates on ongoing efforts.

Reducing the Risk of Tick-Borne Diseases through Smart, Safe and Sustainable Pest Control

EPA Pesticide Factsheets

Each year PestWise programs form new partnerships to address ongoing and emerging issues. Reducing the risk from ticks and tick-borne disease is an issue of importance and EPA is contributing to a larger federal effort.

Braille Goes to High School.

ERIC Educational Resources Information Center

Amato, Sheila

2003-01-01

This brief report describes the development and implementation of a unique, full-year, credit-bearing, technology course in literary Braille transcription offered at a Long Island (New York) high school. It describes the program's goals, development, implementation, students, ongoing activities, outreach efforts, and student attitudes. Suggestions…

Data Validation and Sharing in a Large Research Program

EPA Science Inventory

Appropriate data handling practices are important in the support of large research teams with shifting and competing priorities. Determining those best practices is an ongoing effort for the US EPA’s National Aquatic Resource Surveys. We focus on the well understood data ...

Quantifying uncertainty in read-across assessment – an algorithmic approach - (SOT)

EPA Science Inventory

Read-across is a popular data gap filling technique within category and analogue approaches for regulatory purposes. Acceptance of read-across remains an ongoing challenge with several efforts underway for identifying and addressing uncertainties. Here we demonstrate an algorithm...

DOE Office of Scientific and Technical Information (OSTI.GOV)

Not Available

This program summary describes each of the DOE's Biomass Energy System's projects funded or in existence during fiscal year 1979 and reflects their status as of September 30, 1979. The summary provides an overview of the ongoing research, development, and demonstration efforts of the preceding fiscal year as well. (DMC)

Safety | Argonne National Laboratory

Science.gov Websites

laboratory's ongoing effort to provide a safe and productive environment for employees, users, other site Skip to main content Argonne National Laboratory Toggle Navigation Toggle Search Energy Environment Careers Education Community Diversity Directory Energy Environment National Security User Facilities

HYDRODYNAMIC AND TRANSPORT MODELING STUDY IN A HIGHLY STRATIFIED ESTUARY

EPA Science Inventory

This paper presents the preliminary results of hydrodynamic and salinity predictions and the implications to an ongoing contaminated sediment transport and fate modeling effort in the Lower Duwamish Waterway (LDW), Seattle, Washington. The LDW is highly strati-fied when freshwate...

Validation and application of highway safety manual (part D) in Florida : [summary].

DOT National Transportation Integrated Search

2014-02-01

Ongoing surveillance programs on roads and : highways in the U.S. have produced large amounts : of data on many aspects of transportation. : Crash statistics are among the most important : products of these efforts as they help engineers : pinpoint c...

Reggio Social Capital

ERIC Educational Resources Information Center

Stejzygier, Aneta

2009-01-01

The paper presents the social capital as the essential element of success of the Reggio Emilia preschools known for their unique approach to the early childhood education. The collaborative effort is introduced through examples of the currently ongoing "Reggio Narrates" project of Reggio preschools, the "Dialogue with the…

76 FR 34252 - Notice Pursuant to the National Cooperative Research and Production Act of 1993; ASTM...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-13

... Production Act of 1993; ASTM International Standards Notice is hereby given that, on May 11, 2011, pursuant... seq. (``the Act''), ASTM International Standards (``ASTM'') has filed written notifications.... Specifically, ASTM has provided an updated list of current, ongoing ASTM standards activities originating...

76 FR 12370 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-ASTM...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-03-07

... Production Act of 1993--ASTM International Standards Notice is hereby given that, on February 4, 2011... seq. (``the Act''), ASTM International Standards (``ASTM'') has filed written notifications.... Specifically, ASTM has provided an updated list of current, ongoing ASTM standards activities originating...

Generalizing across Borders: Policy and the Limits of Educational Science

ERIC Educational Resources Information Center

Luke, Allan

2011-01-01

This essay is a critique of the scientific and policy rationales for transnational standardization. It analyzes two examples of policy export: early childhood standards in one of North America's oldest Indigenous communities and the ongoing development of international standards for university teaching. It examines calls for American education to…

76 FR 63509 - Small Business Size Standards: Administrative and Support, Waste Management and Remediation Services

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-12

... Small Business Size Standards: Administrative and Support, Waste Management and Remediation Services... Standards: Administrative and Support, Waste Management and Remediation Services AGENCY: U.S. Small Business...) Sector 56, Administrative and Support, Waste Management and Remediation Services. As part of its ongoing...

Hydrothermal monitoring in a quiescent volcanic arc: Cascade Range, northwestern United States

USGS Publications Warehouse

Ingebritsen, S.E.; Randolph-Flagg, N. G.; Gelwick, K.D.; Lundstrom, E.A.; Crankshaw, I.M.; Murveit, A.M.; Schmidt, M.E.; Bergfeld, D.; Spicer, K.R.; Tucker, D.S.; Mariner, R.H.; Evans, William C.

2014-01-01

Ongoing (1996–present) volcanic unrest near South Sister, Oregon, is accompanied by a striking set of hydrothermal anomalies, including elevated temperatures, elevated major ion concentrations, and 3He/4He ratios as large as 8.6 RA in slightly thermal springs. These observations prompted the US Geological Survey to begin a systematic hydrothermal-monitoring effort encompassing 25 sites and 10 of the highest-risk volcanoes in the Cascade volcanic arc, from Mount Baker near the Canadian border to Lassen Peak in northern California. A concerted effort was made to develop hourly, multiyear records of temperature and/or hydrothermal solute flux, suitable for retrospective comparison with other continuous geophysical monitoring data. Targets included summit fumarole groups and springs/streams that show clear evidence of magmatic influence in the form of high 3He/4He ratios and/or anomalous fluxes of magmatic CO2 or heat. As of 2009–2012, summit fumarole temperatures in the Cascade Range were generally near or below the local pure water boiling point; the maximum observed superheat was 3 during periods of hourly record. Hydrothermal responses to these small seismic stimuli were generally undetectable or ambiguous. Evaluation of multiyear to multidecadal trends indicates that whereas the hydrothermal system at Mount St. Helens is still fast-evolving in response to the 1980–present eruptive cycle, there is no clear evidence of ongoing long-term trends in hydrothermal activity at other Cascade Range volcanoes that have been active or restless during the past century (Baker, South Sister, and Lassen). Experience gained during the Cascade Range hydrothermal-monitoring experiment informs ongoing efforts to capture entire unrest cycles at more active but generally less accessible volcanoes such as those in the Aleutian arc.

The role of CT in professionalism: accreditation, certification and the welfare of our children.

PubMed

Frush, Donald P

2011-09-01

Defining, measuring and promoting professionalism in medicine, including radiology, has been increasingly emphasized by organizations such as ACGME, the ACR and ABR. It is clear that we as imaging experts have as an ultimate responsibility the welfare of our patients. This is the essence of professionalism, and major societies such as the ACR, ABR and RSNA are embracing professionalism through ongoing safety and training efforts. Some of those efforts in accreditation of equipment and certification of medical professionals will be discussed.

Progress Toward HIV Eradication: Case Reports, Current Efforts, and the Challenges Associated with Cure.

PubMed

Martin, Alyssa R; Siliciano, Robert F

2016-01-01

An estimated 35 million people worldwide are infected with HIV, yet a widely applicable cure strategy remains elusive. Recent case reports have suggested that curing HIV infection is possible, renewing excitement about research efforts. We describe those cases and discuss their relevance to the global HIV epidemic. We also review ongoing cure strategies that are transitioning from the lab to the clinic, and the assays and clinical assessments that can be used to evaluate cure interventions.

Student laboratory reports: an approach to improving feedback and quality

NASA Astrophysics Data System (ADS)

Ellingsen, Pål Gunnar; Støvneng, Jon Andreas

2018-05-01

We present an ongoing effort in improving the quality of laboratory reports written by first and second year physics students. The effort involves a new approach where students are given the opportunity to submit reports at intermediate deadlines, receive feedback, and then resubmit for the final deadline. In combination with a differential grading system, instead of pass/fail, the improved feedback results in higher quality reports. Improvement in the quality of the reports is visible through the grade statistics.

Avionics Architectures for Exploration: Wireless Technologies and Human Spaceflight

NASA Technical Reports Server (NTRS)

Goforth, Montgomery B.; Ratliff, James E.; Barton, Richard J.; Wagner, Raymond S.; Lansdowne, Chatwin

2014-01-01

The authors describe ongoing efforts by the Avionics Architectures for Exploration (AAE) project chartered by NASA's Advanced Exploration Systems (AES) Program to evaluate new avionics architectures and technologies, provide objective comparisons of them, and mature selected technologies for flight and for use by other AES projects. The AAE project team includes members from most NASA centers and from industry. This paper provides an overview of recent AAE efforts, with particular emphasis on the wireless technologies being evaluated under AES to support human spaceflight.

Review and Synopsis of Natural and Human Controls on Fluvial Channel Processes in the Arid West

DTIC Science & Technology

2007-09-01

Parallel to ongoing efforts to revise the U.S. Army Corps of Engineers wetland delineation manual for support of Section 404 under the Clean Water ...Act, the Corps has initiated an effort to develop an Ordinary High Water (OHW) delineation manual. The Arid West region is dominated by watersheds with...features. With a better understanding of the stream dynamics associated with regulated ordinary events, the Corps is now developing OHW functional models

The early Earth Observing System reference handbook: Earth Science and Applications Division missions, 1990-1997

NASA Technical Reports Server (NTRS)

1990-01-01

Prior to the launch of the Earth Observing System (EOS) series, NASA will launch and operate a wide variety of new earth science satellites and instruments, as well as undertake several efforts collecting and using the data from existing and planned satellites from other agencies and nations. These initiatives will augment the knowledge base gained from ongoing Earth Science and Applications Division (ESAD) programs. This volume describes three sets of ESAD activities -- ongoing exploitation of operational satellite data, research missions with upcoming launches between now and the first launch of EOS, and candidate earth probes.

Development of Gene Therapy for Thalassemia

PubMed Central

Nienhuis, Arthur W.; Persons, Derek A.

2012-01-01

Retroviral vector–mediated gene transfer into hematopoietic stem cells provides a potentially curative therapy for severe β-thalassemia. Lentiviral vectors based on human immunodeficiency virus have been developed for this purpose and have been shown to be effective in curing thalassemia in mouse models. One participant in an ongoing clinical trial has achieved transfusion independence after gene transfer into bone marrow stem cells owing, in part, to a genetically modified, dominant clone. Ongoing efforts are focused on improving the efficiency of lentiviral vector–mediated gene transfer into stem cells so that the curative potential of gene transfer can be consistently achieved. PMID:23125203

A Sandbox Environment for the CSM Standard and SPICE

NASA Astrophysics Data System (ADS)

Hare, T. M.; Laura, J. R.

2018-04-01

We present ongoing work USGS is undertaking to provide a programming environment for the Camera Sensor Model (CSM) standard and associated SPICE information. This allows for instrument testing and experimentation outside a given production area.

Final report, on-going key comparison BIPM.QM-K1: ozone at ambient level, comparison with DMDM, July 2015

NASA Astrophysics Data System (ADS)

Viallon, J.; Moussay, P.; Wielgosz, R.; Bebic, J.; Norris, J. E.; Guenther, F.

2016-01-01

As part of the on-going key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of the Directorate of Measures and Precious Metals (DMDM) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM), via a transfer standard maintained by the National Institute of Standards and Technology (NIST). The instruments have been compared over a nominal ozone amount-of-substance fraction range of 0 nmol/mol to 500 nmol/mol Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Vehicle postmortem and data analysis of a passenger rail car collision test

DOT National Transportation Integrated Search

2002-04-23

There is an ongoing research program in the United States to investigate and improve rail equipment crashworthiness. As part of this effort, a series of full-scale rail vehicle crash tests are being performed to investigate the crash response of exis...

Plant distributions along salinity and tidal gradients in Oregon tidal marshes

EPA Science Inventory

Accurately modeling climate change effects on tidal marshes in the Pacific Northwest requires understanding how plant assemblages and species are presently distributed along gradients of salinity and tidal inundation. We outline on-going field efforts by the EPA and USGS to dete...

Leaders in School Social Work: Lela B. Costin.

ERIC Educational Resources Information Center

Anderson, Richard J.

1996-01-01

Profiles the accomplishments of a pioneer in school social work research and education. Tells how she balanced home life with professional life. Highlights her ongoing efforts to subsume school social work as a part of child welfare and the mental health of children. (RJM)

DESIGNING MONITORING AND ASSESSMENT STRATEGIES TO INCLUDE NEARSHORE ECOSYSTEMS OF THE GREAT LAKES

EPA Science Inventory

An expectation for monitoring and assessment of very large aquatic systems is that we can develop a strategy that recognizes and reports on ecologically-important subareas using spatially-stratified, probabilistic sampling designs. Ongoing efforts monitor the main-body, offshore ...

Who asks questions at astronomy meetings?

NASA Astrophysics Data System (ADS)

Schmidt, Sarah J.; Davenport, James R. A.

2017-06-01

Over the last decade, significant attention has been drawn to the gender ratio of speakers at conferences, with ongoing efforts for meetings to better reflect the gender representation in the field. We find that women are significantly under-represented, however, among the astronomers asking questions after talks.

ESP IMPROVEMENTS AT POWER PLANTS

EPA Science Inventory

An on-going ORD and OIA collaborative project in the Newly Independent States (NIS) is designed to upgrade ESPs used in NIS power plants and has laid the foundation for implementing cost-effective ESP modernization efforts at power plants. Thus far, state-of-the-art ESP performan...

Meta-Evaluation

ERIC Educational Resources Information Center

Stufflebeam, Daniel L.

2011-01-01

Good evaluation requires that evaluation efforts themselves be evaluated. Many things can and often do go wrong in evaluation work. Accordingly, it is necessary to check evaluations for problems such as bias, technical error, administrative difficulties, and misuse. Such checks are needed both to improve ongoing evaluation activities and to assess…

HiRISE Characterization of Thermophysical Units at Acidalia Planitia, Mars

NASA Astrophysics Data System (ADS)

Martinez-Alonso, S.; Mellon, M. T.; Rafkin, S. C. R.; Zurek, R. W.; McEwen, A. S.; Putzig, N. E.; Searls, M. L.; HiRISE Team

2008-03-01

As part of an ongoing effort to characterize with HiRISE data the global thermophysical units in Mars, we report results regarding a region of Acidalia Planitia, which includes the largest outcrop of thermophysical unit F (rocks, bedrock, duricrust) on the planet.

XENOBIOTIC INDUCED ORGAN-SPECIFIC GENE EXPRESSION AND MACRO/MICROARRAY DEVELOPMENT IN MEDAKA (ORYZIAS LATIPES)

EPA Science Inventory

As part of an ongoing effort to understand and address the short and long-term consequences of increasing levels of environmental contaminants, we used suppressive subtractive hydridization (SSH) to develop gene expression profiles from Japanese medaka (Oryzias latipes) exposed ...

76 FR 56128 - Retrospective Review of Existing Regulations

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-12

..., welfare, safety, and our environment while promoting economic growth, innovation, competitiveness, and job creation.'' In furtherance of its ongoing efforts to update regulations to reflect market developments and... Commission in considering the development of a plan for the retrospective review of its regulations. DATES...

76 FR 33065 - Adaptation of Regulations to Incorporate Swaps

Federal Register 2010, 2011, 2012, 2013, 2014

2011-06-07

... retention period for any communication medium (e.g., oral communications) should be shorter than the... Commission's] ongoing efforts to facilitate the use of electronic technology and media'') \\45\\ applies... on electronic storage media, provided, however, that for electronic records, the storage media must...

Syria: health in a country undergoing tragic transition.

PubMed

Ben Taleb, Ziyad; Bahelah, Raed; Fouad, Fouad M; Coutts, Adam; Wilcox, Meredith; Maziak, Wasim

2015-01-01

To document the ongoing destruction as a result of the tragic events in Syria, to understand the changing health care needs and priorities of Syrians. A directed examination of the scientific literature and reports about Syria before and during the Syrian conflict, in addition to analyzing literature devoted to the relief and rebuilding efforts in crisis situations. The ongoing war has had high direct war casualty, but even higher suffering due to the destruction of health system, displacement, and the breakdown of livelihood and social fabric. Millions of Syrians either became refugees or internally displaced, and about half of the population is in urgent need for help. Access to local and international aid organizations for war-affected populations is an urgent and top priority. Syrians continue to endure one of the biggest human tragedies in modern times. The extent of the crisis has affected all aspects of Syrians' life. Understanding the multi-faceted transition of the Syrian population and how it reflects on their health profile can guide relief and rebuilding efforts' scope and priorities.

Novel Concepts for HIV Vaccine Vector Design.

PubMed

Alayo, Quazim A; Provine, Nicholas M; Penaloza-MacMaster, Pablo

2017-01-01

The unprecedented challenges of developing effective vaccines against intracellular pathogens such as HIV, malaria, and tuberculosis have resulted in more rational approaches to vaccine development. Apart from the recent advances in the design and selection of improved epitopes and adjuvants, there are also ongoing efforts to optimize delivery platforms. Viral vectors are the best-characterized delivery tools because of their intrinsic adjuvant capability, unique cellular tropism, and ability to trigger robust adaptive immune responses. However, a known limitation of viral vectors is preexisting immunity, and ongoing efforts are aimed at developing novel vector platforms with lower seroprevalence. It is also becoming increasingly clear that different vectors, even those derived from phylogenetically similar viruses, can elicit substantially distinct immune responses, in terms of quantity, quality, and location, which can ultimately affect immune protection. This review provides a summary of the status of viral vector development for HIV vaccines, with a particular focus on novel viral vectors and the types of adaptive immune responses that they induce.

MIT research in telerobotics

NASA Technical Reports Server (NTRS)

Sheridan, T. B.

1987-01-01

Ongoing MIT research in telerobotics (vehicles capable of some autonomous sensing and manipulating, having some remote supervisory control by people) and teleoperation (vehicles for sensing and manipulating which are fully controlled remotely by people) is discussed. The current efforts mix human and artificial intelligence/control. The idea of adjustable impedance at either end of pure master-slave teleoperation, and simultaneous coordinated control of teleoperator/telerobotic systems which have more than six degrees of freedom (e.g., a combined vehicle and arm, each with five or six DOF) are discussed. A new cable-controlled parallel link arm which offers many advantages over conventional arms for space is briefly described. Predictor displays to compensate for time delay in teleoperator loops, the use of state estimation to help human control decisions in space, and ongoing research in supervisory command language are covered. Finally, efforts to build a human flyable real-time dynamic computer-graphic telerobot simulator are described. These projects represent most, but not all, of the telerobotics research in our laboratory, supported by JPL, NASA Ames and NOAA.

Development of data representation standards by the human proteome organization proteomics standards initiative

PubMed Central

Albar, Juan Pablo; Binz, Pierre-Alain; Eisenacher, Martin; Jones, Andrew R; Mayer, Gerhard; Omenn, Gilbert S; Orchard, Sandra; Vizcaíno, Juan Antonio; Hermjakob, Henning

2015-01-01

Objective To describe the goals of the Proteomics Standards Initiative (PSI) of the Human Proteome Organization, the methods that the PSI has employed to create data standards, the resulting output of the PSI, lessons learned from the PSI’s evolution, and future directions and synergies for the group. Materials and Methods The PSI has 5 categories of deliverables that have guided the group. These are minimum information guidelines, data formats, controlled vocabularies, resources and software tools, and dissemination activities. These deliverables are produced via the leadership and working group organization of the initiative, driven by frequent workshops and ongoing communication within the working groups. Official standards are subjected to a rigorous document process that includes several levels of peer review prior to release. Results We have produced and published minimum information guidelines describing what information should be provided when making data public, either via public repositories or other means. The PSI has produced a series of standard formats covering mass spectrometer input, mass spectrometer output, results of informatics analysis (both qualitative and quantitative analyses), reports of molecular interaction data, and gel electrophoresis analyses. We have produced controlled vocabularies that ensure that concepts are uniformly annotated in the formats and engaged in extensive software development and dissemination efforts so that the standards can efficiently be used by the community. Conclusion In its first dozen years of operation, the PSI has produced many standards that have accelerated the field of proteomics by facilitating data exchange and deposition to data repositories. We look to the future to continue developing standards for new proteomics technologies and workflows and mechanisms for integration with other omics data types. Our products facilitate the translation of genomics and proteomics findings to clinical and biological phenotypes. The PSI website can be accessed at http://www.psidev.info. PMID:25726569

Detecting ongoing intimate partner violence in the emergency department using a simple 4-question screen: the OVAT.

PubMed

Ernst, Amy A; Weiss, Steven J; Cham, Elaine; Hall, Louise; Nick, Todd G

2004-06-01

We wanted to prospectively evaluate the use of a brief screening tool for ongoing intimate partner violence (IPV), the OVAT, and to validate this tool against the present Index of Spouse Abuse (ISA). The design was a prospective survey during randomized 4-hour shifts in an urban emergency department setting. The scale consists of four questions developed based on our previous work. The ISA was compared as the gold standard for detection of present (ongoing) IPV. Of 362 eligible patients presenting during 75 randomized 4-hour shifts, 306 (85%) completed the study. The prevalence of ongoing IPV using the OVAT was 31% (95% CI 26% to 36%). For the ISA, the prevalence was 20% (95% CI 16% to 25%). Compared with the ISA, the sensitivity of the OVAT in detecting ongoing IPV was 86%, specificity 83%, negative predictive value 96%, positive predictive value 56%, with an accuracy of 84%. In conclusion, four brief questions can detect ongoing IPV to aid in identifying the victim.

77 FR 71163 - Federal Motor Vehicle Safety Standards; Windshield Zone Intrusion

Federal Register 2010, 2011, 2012, 2013, 2014

2012-11-29

...-models pre-standard and post-standard. The report found no measurable or determinable weight or cost per... determined that there are two ongoing regulatory developments that could influence vehicle designs by putting... vehicles. As a result, the agency believes that vehicle designs with regard to the hood and windshield are...

25 CFR 1000.396 - Does a Tribe/Consortium have additional ongoing requirements to maintain minimum standards for...

Code of Federal Regulations, 2010 CFR

2010-04-01

... requirements to maintain minimum standards for Tribe/Consortium management systems? 1000.396 Section 1000.396... AGREEMENTS UNDER THE TRIBAL SELF-GOVERNMENT ACT AMENDMENTS TO THE INDIAN SELF-DETERMINATION AND EDUCATION ACT... minimum standards for Tribe/Consortium management systems? Yes, the Tribe/Consortium must maintain...

77 FR 14046 - Amended Notice Pursuant to the National Cooperative Research and Production Act of 1993-ASTM...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-03-08

... Research and Production Act of 1993--ASTM International Standards Notice is hereby given that, on February..., 15 U.S.C. 4301 et seq. (``the Act''), ASTM International Standards (``ASTM'') has filed written... circumstances. Specifically, ASTM has provided an updated list of current, ongoing ASTM standards activities...

Tomorrow Is Today at Silver Ridge.

ERIC Educational Resources Information Center

Wise, B. J.

1994-01-01

Describes a Washington State school's efforts to forego factory-model education for a boldly restructured curriculum dependent on new technologies, such as computer networks, two-year classrooms, ongoing staff development and planning sessions, and an innovative onsite day-care program for staff and students. The school has succeeded in…

Transforming Schools through Total Quality Education.

ERIC Educational Resources Information Center

Schmoker, Mike; Wilson, Richard B.

1993-01-01

Deming's work emphasizes advantages of teamwork, investment in ongoing training for all employees to increase their value to the company, and insistence that research and employee-gathered data guide and inform every decision and improvement effort. The parallel between psychologist Mihaly Csikszenmihalyi's work and Deming's shows that Total…

Determination of fluorotelomer alcohols in selected consumer products and preliminary investigation of their fate in the indoor environment

EPA Science Inventory

The U.S. Environmental Protection Agency (EPA) has established an ongoing effort to identify the major perfluorocarboxylic acid (PFCA) sources in nonoccupational indoor environments and characterize their transport and fate. This study determined the concentrations of perfluorote...

Mass balance and swath displacement evaluations from agricultural application field trials

USDA-ARS?s Scientific Manuscript database

Spray drift is on an ongoing concern for any agricultural application and continues to be the focus for new developments and research efforts dealing with drift reduction technologies, best management application practices and the development of new decision support systems for applicators. Typical...

Climate Change Portal - Home Page

Science.gov Websites

impacts on California's economy and environment. California's unique and valuable natural treasures emissions. Local governments are at the forefront of efforts to adapt to the ongoing and anticipated impacts climate change impacts and informing policies to reduce greenhouse gases, adapt to changing environments

Chapter 1: An Introduction to the Saber-Tooth Project.

ERIC Educational Resources Information Center

Ward, Phillip

1999-01-01

Introduces a theme issue on the Saber-Tooth Project, an ongoing reform effort involving a university and school district that collaborate to improve middle school physical education by improving teaching conditions and engaging teachers in professional development emphasizing curriculum improvement. The monograph explains the nature of…

Reproductive and developmental biology of the emerald ash borer parasitoid Spathius galinae (Hymenoptera: Braconidae) as affected by temperature

USDA-ARS?s Scientific Manuscript database

Emerald ash borer Agrilus planipennis Fairmaire (Coleoptera: Buprestidae) is an invasive pest of serious concern in North America. To complement ongoing biological control efforts, Spathius galinae Belokobylskij and Strazenac (Hymenoptera: Braconidae), a recently-described specialist parasitoid of ...

Ozone Layer Educator's Guide.

ERIC Educational Resources Information Center

Environmental Protection Agency, Washington, DC.

This guide has been developed through a collaborative effort involving the U.S. Environmental Protection Agency (EPA), the National Oceanic and Atmospheric Administration (NOAA), and the National Aeronautics and Space Administration (NASA). It is part of an ongoing commitment to ensure that the results of scientific research on ozone depletion are…

GOALS AND CURRENT RESEARCH OF EPA'S STREAM RESTORATION RESEARCH PROGRAM

EPA Science Inventory

The US EPA is involved in ongoing research on stream and riparian restoration. This presentation is designed to discuss current EPA research efforts, identify key issues in the science and practice of stream restoration, and to help frame a future National Research Council study...

News about Newborn Screening

ERIC Educational Resources Information Center

Exceptional Parent, 2007

2007-01-01

For years "Exceptional Parent" ("EP") has been offering educational information and support to those challenged with disabilities and takes an equally pro-active role in disseminating vital information that could potentially prevent disabilities. This is evidenced by its past and ongoing efforts in being a proponent and champion for comprehensive…

Development of a decision support tool to better manage Alabama's rural public transit vehicles

DOT National Transportation Integrated Search

2000-01-01

In an ongoing effort to improve mobility and quality of life for Alabama's citizens, researchers at the University of Alabama in Huntsville are working to improve the state's ability to manage its rural transit fleet. This fleet management consists o...

The First Attempts to Unionize the Faculty

ERIC Educational Resources Information Center

Cain, Timothy Reese

2010-01-01

Background/Context: Faculty unionization is an important topic in modern higher education, but the history of the phenomenon has not yet been fully considered. This article brings together issues of professionalization and unionization and provides needed historical background to ongoing unionization efforts and debates. Purpose/Objective/Research…

BRAVO (Brazilian Astrophysical Virtual Observatory): data mining development

NASA Astrophysics Data System (ADS)

De Carvalho, R. R.; Capelato, H. V.; Velho, H. C.

2007-08-01

The primary goal of the BRAVO project is to generate investment in information technology, with particular emphasis on datamining and statistical analysis. From a scientific standpoint, the participants assembled to date are engaged in several scientific projects in various fields of cosmology, astrophysics, and data analysis, with significant contributions from international partners. These scientists conduct research on clusters of galaxies, small groups of galaxies, elliptical galaxies, population synthesis, N-body simulations, and a variety of studies in stellar astrophysics. One of the main aspects of this project is the incorporation of these disparate areas of astrophysical research within the context of the coherent development of database technology.Observational cosmology is one of the branches of science experiencing the largest growth in the past few decades. large photometric and spectroscopic surveys have been carried out in both hemispheres. As a result, an extraordinary amount of data in all portions of the electromagnetic spectrum exists, but without standard techniques for storage and distribution. This project will utilize several specific astronomical databases, created to store data generated by several instruments (including SOAR, Gemini, BDA, etc), uniting them within a common framework and with standard interfaces. We are inviting members of the entire Brazilian astronomical community to partake in this effort. This will certainly impact both education and outreach efforts, as well as the future development of astrophysical research. Finally, this project will provide a constant investment in human resources. First, it will do so by stimulating ongoing short technical visits to Johns Hopkins University and Caltech. These will allow us to bring software technology and expertise in datamining back to Brazil. Second, we will organize the Summer School on Software Technology in Astrophysics, which will be designed to ensure that the Brazilian scientific community can take full advantage of the benefits offered by the VO project

Navigating the Rapids: The Development of Regulated Next-Generation Sequencing-Based Clinical Trial Assays and Companion Diagnostics

PubMed Central

Pant, Saumya; Weiner, Russell; Marton, Matthew J.

2014-01-01

Over the past decade, next-generation sequencing (NGS) technology has experienced meteoric growth in the aspects of platform, technology, and supporting bioinformatics development allowing its widespread and rapid uptake in research settings. More recently, NGS-based genomic data have been exploited to better understand disease development and patient characteristics that influence response to a given therapeutic intervention. Cancer, as a disease characterized by and driven by the tumor genetic landscape, is particularly amenable to NGS-based diagnostic (Dx) approaches. NGS-based technologies are particularly well suited to studying cancer disease development, progression and emergence of resistance, all key factors in the development of next-generation cancer Dxs. Yet, to achieve the promise of NGS-based patient treatment, drug developers will need to overcome a number of operational, technical, regulatory, and strategic challenges. Here, we provide a succinct overview of the state of the clinical NGS field in terms of the available clinically targeted platforms and sequencing technologies. We discuss the various operational and practical aspects of clinical NGS testing that will facilitate or limit the uptake of such assays in routine clinical care. We examine the current strategies for analytical validation and Food and Drug Administration (FDA)-approval of NGS-based assays and ongoing efforts to standardize clinical NGS and build quality control standards for the same. The rapidly evolving companion diagnostic (CDx) landscape for NGS-based assays will be reviewed, highlighting the key areas of concern and suggesting strategies to mitigate risk. The review will conclude with a series of strategic questions that face drug developers and a discussion of the likely future course of NGS-based CDx development efforts. PMID:24860780

State experiences implementing youth sports concussion laws: challenges, successes, and lessons for evaluating impact.

PubMed

Lowrey, Kerri McGowan; Morain, Stephanie R

2014-01-01

While provisions of youth sports concussion laws are very similar, little is known as to how they are being implemented, factors that promote or impede implementation, or the level of compliance in each jurisdiction. We aimed to describe state experiences with implementation in order to inform ongoing efforts to reduce the harm of sports-related traumatic brain injury and to guide future evaluations of the laws' impacts and the development of future public health laws. We conducted key-informant interviews in 35 states with recently enacted concussion legislation. States varied considerably in their readiness and capacity for implementation. Factors facilitating implementation included existing partnerships, procedures, and resources; centralized implementation authority; prior related efforts; and involvement in the policymaking process by those now charged with implementation. Inhibitors included ambiguous statutory language, unclear delegation of authority, and compliance difficulties. Ongoing challenges persist, including primary prevention; determining which providers are qualified to make return-to-play assessments and contents of those assessments; compliance difficulties in rural and under-served areas; and unclear responsibility for enforcement. Despite the similarity of youth sports concussion laws, early evidence suggests there is considerable variation in their implementation. These findings are critical for ongoing empirical investigations to accurately evaluate the laws' provisions and to identify successful legal approaches to protecting young athletes. © 2014 American Society of Law, Medicine & Ethics, Inc.

Apparent annual survival estimates of tropical songbirds better reflect life history variation when based on intensive field methods

USGS Publications Warehouse

Martin, Thomas E.; Riordan, Margaret M.; Repin, Rimi; Mouton, James C.; Blake, William M.

2017-01-01

AimAdult survival is central to theories explaining latitudinal gradients in life history strategies. Life history theory predicts higher adult survival in tropical than north temperate regions given lower fecundity and parental effort. Early studies were consistent with this prediction, but standard-effort netting studies in recent decades suggested that apparent survival rates in temperate and tropical regions strongly overlap. Such results do not fit with life history theory. Targeted marking and resighting of breeding adults yielded higher survival estimates in the tropics, but this approach is thought to overestimate survival because it does not sample social and age classes with lower survival. We compared the effect of field methods on tropical survival estimates and their relationships with life history traits.LocationSabah, Malaysian Borneo.Time period2008–2016.Major taxonPasseriformes.MethodsWe used standard-effort netting and resighted individuals of all social and age classes of 18 tropical songbird species over 8 years. We compared apparent survival estimates between these two field methods with differing analytical approaches.ResultsEstimated detection and apparent survival probabilities from standard-effort netting were similar to those from other tropical studies that used standard-effort netting. Resighting data verified that a high proportion of individuals that were never recaptured in standard-effort netting remained in the study area, and many were observed breeding. Across all analytical approaches, addition of resighting yielded substantially higher survival estimates than did standard-effort netting alone. These apparent survival estimates were higher than for temperate zone species, consistent with latitudinal differences in life histories. Moreover, apparent survival estimates from addition of resighting, but not from standard-effort netting alone, were correlated with parental effort as measured by egg temperature across species.Main conclusionsInclusion of resighting showed that standard-effort netting alone can negatively bias apparent survival estimates and obscure life history relationships across latitudes and among tropical species.

Recent progress in MEMS technology development for military applications

NASA Astrophysics Data System (ADS)

Ruffin, Paul B.; Burgett, Sherrie J.

2001-08-01

The recent progress of ongoing efforts at the Army Aviation and Missile Command (AMCOM) to develop microelectromechanical systems (MEMS) technology for military applications is discussed in this paper. The current maturity level of low cost, low power, micro devices in industry, which range from simple temperature and pressure sensors to accelerometers in airbags, provides a viable foundation for the development of rugged MEMS devices for dual-use applications. Early MEMS technology development efforts at AMCOM emphasized inertial MEMS sensors. An Army Science and Technology Objective (STO) project was initiated to develop low cost inertial components with moderate angular rate sensor resolution for measuring pitch and yaw of missile attitude and rotational roll rate. Leveraging the Defense Advanced Research Projects Agency and other Government agencies has resulted in the development of breadboard inertial MEMS devices with improved robustness. During the past two years, MEMS research at AMCOM has been expanded to include environmental MEMS sensors for missile health monitoring, RF-MEMS, optical MEMS devices for beam steering, and micro-optic 'benches' for opto-electronics miniaturization. Additionally, MEMS packaging and integration issues have come into focus and are being addressed. Selected ongoing research efforts in these areas are presented, and some horizon MEMS sensors requirements for Army and law enforcement are presented for consideration.

Nevada National Security Site: Site-Directed Research and Development (SDRD) Fiscal Year 2015 Annual Report

DOE Office of Scientific and Technical Information (OSTI.GOV)

Bender, Howard A.

This report presents results of multiple research projects, new and ongoing, funded under the Site-Directed Research and Development Program for the Nevada National Security Site during federal fiscal year 2015. The Site's legacy capabilities in remote sensing combined with new paradigms for emergency response and consequence management help drive the need to develop advanced aerial sensor platforms. Likewise, dynamic materials science is a critical area of scientific research for which basic physics issues are still unresolved. New methods of characterizing materials in extreme states are vitally needed, and these efforts are paving the way with new knowledge. Projects selected inmore » FY 2015 for the Exploratory Research portfolio exhibit a strong balance of NNSS mission relevance. Geoscience, seismology, and techniques for detecting underground nuclear events are still essential focus areas. Many of the project reports in the second major section of this annual report are ongoing continuations in multi-year lifecycles. Diagnostic techniques for stockpile and nuclear security science figured prominently as well, with a few key efforts coming to fruition, such as phase transition detection. In other areas, modeling efforts toward better understanding plasma focus physics has also started to pay dividends for major program needs.« less

On-Going Laboratory Efforts to Quantitatively Address Clay Abundance on Mars

NASA Technical Reports Server (NTRS)

Roush, Ted L.; Bishop, Janice L.; Brown, Adrian J.; Blake, David F.; Bristow, Thomas F.

2012-01-01

Data obtained at visible and near-infrared wavelengths by OMEGA on MarsExpress and CRISM on MRO provide definitive evidence for the presence of phyllosilicates and other hydrated phases on Mars. A diverse range of both Fe/Mg-OH and Al-OH-bearing phyllosilicates were identified including the smectites, nontronite, saponite, and montmorillonite. In order to constrain the abundances of these phyllosilicates spectral analyses of mixtures are needed. We report on our on-going effort to enable the quantitative evaluation of the abundance of hydrated-hydroxylated silicates when they are contained in mixtures. We include two component mixtures of hydrated/hydroxylated silicates with each other and with two analogs for other martian materials; pyroxene (enstatite) and palagonitic soil (an alteration product of basaltic glass). For the hydrated-hydroxylated silicates we include saponite and montmorillonite (Mg- and Al- rich smectites). We prepared three size separates of each end-member for study: 20-45, 63-90, and 125-150 µm. As the second phase of our effort we used scanning electron microscopy imaging and x-ray diffraction to characterize the grain size distribution, and structural nature, respectively, of the mixtures. Visible and near-infrared reflectance spectra of the 63-90 micrometers grain size of the mixture samples are shown in Figure 1. We discuss the results of our measurements of these mixtures.

Lessons Learned about the Methodology of Economic Impact Studies: The NIST Experience.

ERIC Educational Resources Information Center

Tassey, Gregory

1999-01-01

Summarizes ongoing economic impact assessment activities at the National Institute of Standards and Technology (NIST) for its Measurement and Standards Laboratory Program. Explores designing economic impact studies for integration into assessments of broader programmatic objectives. (SLD)

Rocketdyne PSAM: In-house enhancement/application

NASA Technical Reports Server (NTRS)

Newell, J. F.; Rajagopal, K. R.; Ohara, K.

1991-01-01

The development was initiated of the Probabilistic Design Analysis (PDA) Process for rocket engines. This will enable engineers a quantitative assessment of calculated reliability during the design process. The PDA will help choose better designs, make them more robust, and help decide on critical tests to help demonstrate key reliability issues to aid in improving the confidence of the engine capabilities. Rockedyne's involvement with the Composite Loads Spectra (CLS) and Probabilistic Structural Analysis Methodology (PSAM) contracts started this effort and are key elements in the on-going developments. Internal development efforts and hardware applications complement and extend the CLS and PSAM efforts. The completion of the CLS option work and the follow-on PSAM developments will also be integral parts of this methodology. A brief summary of these efforts is presented.

Design and implementation of an air monitoring program in support of a brownfields redevelopment program

DOE Office of Scientific and Technical Information (OSTI.GOV)

Maisel, B.E.; Hunt, G.T.; Devaney, R.J. Jr.

EPA`s Brownfields Economic Redevelopment Initiative has sparked renewal of industrial and commercial parcels otherwise idled or under-utilized because of real or perceived environmental contamination. In certain cases, restoring such parcels to productive economic use requires a redevelopment effort protective of human health and welfare through minimizing offsite migration of environmental contaminants during cleanup, demolition and remediation activities. To support these objectives, an air monitoring program is often required as an integral element of a comprehensive brownfields redevelopment effort. This paper presents a strategic framework for design and execution of an ambient air monitoring program in support of a brownfields remediationmore » effort ongoing in Lawrence, MA. Based on site characterization, the program included sample collection and laboratory analysis of ambient air samples for polychlorinated biphenyls (PCBs), polychlorinated dibenzodioxins and polychlorinated dibenzofurans (PCDDs/PCDFs), total suspended particulate (TSP), inhalable particulate (PM10), and lead. The program included four monitoring phases, identified as background, wintertime, demolition/remediation and post-demolition. Air sampling occurred over a 16 month period during 1996--97, during which time nine sampling locations were utilized to produce approximately 1,500 ambient air samples. Following strict data review and validation procedures, ambient air data interpretation focused on the following: evaluation of upwind/downwind sample pairs, comparison of ambient levels to existing regulatory standards, relation of ambient levels to data reported in the open literature, and, determination of normal seasonal variations in existing background burden, comparison of ambient levels measured during site activity to background levels.« less

Establishing a professional profile of community health workers: results from a national study of roles, activities and training.

PubMed

Ingram, Maia; Reinschmidt, Kerstin M; Schachter, Ken A; Davidson, Chris L; Sabo, Samantha J; De Zapien, Jill Guernsey; Carvajal, Scott C

2012-04-01

Community Health Workers (CHWs) have gained national recognition for their role in addressing health disparities and are increasingly integrated into the health care delivery system. There is a lack of consensus, however, regarding empirical evidence on the impact of CHW interventions on health outcomes. In this paper, we present results from the 2010 National Community Health Worker Advocacy Survey (NCHWAS) in an effort to strengthen a generalized understanding of the CHW profession that can be integrated into ongoing efforts to improve the health care delivery system. Results indicate that regardless of geographical location, work setting, and demographic characteristics, CHWs generally share similar professional characteristics, training preparation, and job activities. CHWs are likely to be female, representative of the community they serve, and to work in community health centers, clinics, community-based organizations, and health departments. The most common type of training is on-the-job and conference training. Most CHWs work with clients, groups, other CHWs and less frequently community leaders to address health issues, the most common of which are chronic disease, prevention and health care access. Descriptions of CHW activities documented in the survey demonstrate that CHWs apply core competencies in a synergistic manner in an effort to assure that their clients get the services they need. NCHWAS findings suggest that over the past 50 years, the CHW field has become standardized in response to the unmet needs of their communities. In research and practice, the field would benefit from being considered a health profession rather than an intervention.

A physiome interoperability roadmap for personalized drug development

PubMed Central

2016-01-01

The goal of developing therapies and dosage regimes for characterized subgroups of the general population can be facilitated by the use of simulation models able to incorporate information about inter-individual variability in drug disposition (pharmacokinetics), toxicity and response effect (pharmacodynamics). Such observed variability can have multiple causes at various scales, ranging from gross anatomical differences to differences in genome sequence. Relevant data for many of these aspects, particularly related to molecular assays (known as ‘-omics’), are available in online resources, but identification and assignment to appropriate model variables and parameters is a significant bottleneck in the model development process. Through its efforts to standardize annotation with consequent increase in data usability, the human physiome project has a vital role in improving productivity in model development and, thus, the development of personalized therapy regimes. Here, we review the current status of personalized medicine in clinical practice, outline some of the challenges that must be overcome in order to expand its applicability, and discuss the relevance of personalized medicine to the more widespread challenges being faced in drug discovery and development. We then review some of (i) the key data resources available for use in model development and (ii) the potential areas where advances made within the physiome modelling community could contribute to physiologically based pharmacokinetic and physiologically based pharmacokinetic/pharmacodynamic modelling in support of personalized drug development. We conclude by proposing a roadmap to further guide the physiome community in its on-going efforts to improve data usability, and integration with modelling efforts in the support of personalized medicine development. PMID:27051513

Conservation Action Planning: Lessons learned from the St. Marys River watershed biodiversity conservation planning process

USGS Publications Warehouse

Patterson, Tamatha A.; Grundel, Ralph

2014-01-01

Conservation Action Planning (CAP) is an adaptive management planning process refined by The Nature Conservancy (TNC) and embraced worldwide as the Open Standards for the Practice of Conservation. The CAP process facilitates open, multi-institutional collaboration on a common conservation agenda through organized actions and quantified results. While specifically designed for conservation efforts, the framework is adaptable and flexible to multiple scales and can be used for any collaborative planning effort. The CAP framework addresses inception; design and development of goals, measures, and strategies; and plan implementation and evaluation. The specific components of the CAP include defining the project scope and conservation targets; assessing the ecological viability; ascertaining threats and surrounding situation; identifying opportunities and designing strategies for action; and implementing actions and monitoring results. In 2007, TNC and a multidisciplinary graduate student team from the University of Michigan's School of Natural Resources and Environment initiated a CAP for the St. Marys River, the connecting channel between Lake Superior and Lake Huron, and its local watershed. The students not only gained experience in conservation planning, but also learned lessons that notably benefited the CAP process and were valuable for any successful collaborative effort—a dedicated core team improved product quality, accelerated the timeline, and provided necessary support for ongoing efforts; an academic approach in preparation for engagement in the planning process brought applicable scientific research to the forefront, enhanced workshop facilitation, and improved stakeholder participation; and early and continuous interactions with regional stakeholders improved cooperation and built a supportive network for collaboration.

A global review of freshwater crayfish temperature tolerance, preference, and optimal growth

USGS Publications Warehouse

Westhoff, Jacob T.; Rosenberger, Amanda E.

2016-01-01

Conservation efforts, environmental planning, and management must account for ongoing ecosystem alteration due to a changing climate, introduced species, and shifting land use. This type of management can be facilitated by an understanding of the thermal ecology of aquatic organisms. However, information on thermal ecology for entire taxonomic groups is rarely compiled or summarized, and reviews of the science can facilitate its advancement. Crayfish are one of the most globally threatened taxa, and ongoing declines and extirpation could have serious consequences on aquatic ecosystem function due to their significant biomass and ecosystem roles. Our goal was to review the literature on thermal ecology for freshwater crayfish worldwide, with emphasis on studies that estimated temperature tolerance, temperature preference, or optimal growth. We also explored relationships between temperature metrics and species distributions. We located 56 studies containing information for at least one of those three metrics, which covered approximately 6 % of extant crayfish species worldwide. Information on one or more metrics existed for all 3 genera of Astacidae, 4 of the 12 genera of Cambaridae, and 3 of the 15 genera of Parastacidae. Investigations employed numerous methodological approaches for estimating these parameters, which restricts comparisons among and within species. The only statistically significant relationship we observed between a temperature metric and species range was a negative linear relationship between absolute latitude and optimal growth temperature. We recommend expansion of studies examining the thermal ecology of freshwater crayfish and identify and discuss methodological approaches that can improve standardization and comparability among studies.

Sports Injury Surveillance Systems: A Review of Methods and Data Quality.

PubMed

Ekegren, Christina L; Gabbe, Belinda J; Finch, Caroline F

2016-01-01

Data from sports injury surveillance systems are a prerequisite to the development and evaluation of injury prevention strategies. This review aimed to identify ongoing sports injury surveillance systems and determine whether there are gaps in our understanding of injuries in certain sport settings. A secondary aim was to determine which of the included surveillance systems have evaluated the quality of their data, a key factor in determining their usefulness. A systematic search was carried out to identify (1) publications presenting methodological details of sports injury surveillance systems within clubs and organisations; and (2) publications describing quality evaluations and the quality of data from these systems. Data extracted included methodological details of the surveillance systems, methods used to evaluate data quality, and results of these evaluations. Following literature search and review, a total of 15 sports injury surveillance systems were identified. Data relevant to each aim were summarised descriptively. Most systems were found to exist within professional and elite sports. Publications concerning data quality were identified for seven (47%) systems. Validation of system data through comparison with alternate sources has been undertaken for only four systems (27%). This review identified a shortage of ongoing injury surveillance data from amateur and community sport settings and limited information about the quality of data in professional and elite settings. More surveillance systems are needed across a range of sport settings, as are standards for data quality reporting. These efforts will enable better monitoring of sports injury trends and the development of sports safety strategies.

The Strengths and Difficulties Questionnaire in the Nordic countries.

PubMed

Obel, Carsten; Heiervang, Einar; Rodriguez, Alina; Heyerdahl, Sonja; Smedje, Hans; Sourander, André; Guethmundsson, Olafur O; Clench-Aas, Jocelyne; Christensen, Else; Heian, Frode; Mathiesen, Kristin S; Magnússon, Páll; Njarethvík, Urethur; Koskelainen, Merja; Rønning, John A; Stormark, Kjell Morten; Olsen, Jørn

2004-01-01

The Strengths and Difficulties Questionnaire (SDQ) has been translated into the different Nordic languages between 1996 and 2003. During the past few years, SDQs have been completed for nearly 100,000 children and adolescents in population-based studies as well as in clinical samples. The largest studies have been performed in Norway and Denmark, and in these countries the diagnostic interview DAWBA has also been used in conjunction with the SDQ. In addition to a brief overview of past and ongoing SDQ work in Sweden, Finland, Norway, Denmark, and Iceland, we present scale means and standard deviations from selected community studies with comparable age groups, including parental reports for 7, 9 and 11 year-old children and self-reports of 13 and 15 year-olds. The descriptive statistics suggest that the distributions of SDQ scores are very similar across the Nordic countries. Further collaborative efforts in establishing norms and evaluating the validity of the SDQ as a screening instrument are encouraged.

Report on SARS backfit evaluation, Catalytic, Inc. Solvent Refined Coal Pilot Plant, Wilsonville, Alabama

DOE Office of Scientific and Technical Information (OSTI.GOV)

Meyer, A.F. Jr.

1980-07-02

A site visit was made in company with the DOE-OPTA-EA Safety and Health Official for the purpose of providing that official with technical assistance in evaluating the validity of an earlier DOE-OPTA recommendation exempting this facility from the Safety and Analysis and Review backfit requirements of DOE Order 5481.1. A further purpose of the visit was to assess and evaluate the occupational safety and health program at this facility, as compared with the criteria and guidelines contained in ASFE Order 5481.1. Adequate documentation regarding compliance with codes, standards, and regulations were observed at this facility. There is in existence anmore » ongoing continuous safety analysis effort for both modifications or additions to this facility. Adequate environmental safeguards and plans and procedures were observed. The SARS backfit exemption is appropriate. The occupational safety and health program is in many ways a model for the scope of work and nature of hazards involved, and is consistent with ASFE guidelines and statutory requirements.« less

A novel management of streptococcal pharyngotonsillar infections by laser-activated silver nanoparticles and methylene blue conjugate, in vitro study.

PubMed

Kassab, Ahmed; Dabous, Ola; Morsy, Mona

2017-09-01

Species of Streptococcus are classified based on their hemolytic properties into alpha and beta types. And, since antimicrobial drug resistance is an increasingly problematic issue, the efforts to develop modalities that would overcome this obstacle and avoid antibiotic side effects is an ongoing challenge. 20 patients from both sexes were selected. The isolated organisms were identified according to standard laboratory methods. Bacterial Cultures were subjected to the low-level diode laser (660 nm), methylene blue (MB) as a photosensitizing agent and for silver nanoparticles. All the experimental groups showed statistically lower values of CFU/ml than the positive control group. The photoactivated MB, silver nanoparticles conjugate showed the maximum inhibitory effect on Streptococci, which opens a gate to further investigation of such a promising protocol to establish a safe and efficient method of management for resistant cases of streptococcal tonsillar infections. Copyright © 2017 Elsevier B.V. All rights reserved.

The continuing role of chemotherapy for advanced non-small cell lung cancer in the targeted therapy era.

PubMed

Lwin, Zarnie; Riess, Jonathan W; Gandara, David

2013-10-01

There have been remarkable advances in the targeted treatment of advanced non-small cell lung cancer (NSCLC) over the past several years. Survival outcomes are steadily improving as management paradigms shift in the diagnosis and treatment of advanced NSCLC. Customizing treatment based on histology and molecular typing has become a standard of care in this era of targeted therapy. While new chemotherapeutic agents have proven effective, the pivotal role of platinum-based chemotherapy doublets has been confirmed. Maintenance chemotherapy has become an option, but who to employ it in remains unclear in the real-world setting. Efforts to overcome resistance to targeted agents are ongoing utilizing combination regimens of chemotherapy plus targeted agents, but optimizing combination strategies needs further exploration. This review highlights recent developments in novel chemotherapeutics and in chemotherapy strategies over the past two years. Despite advances in molecular medicine, there remains an essential role for chemotherapy in advanced NSCLC, even in the recent targeted therapy era.

STRBase: a short tandem repeat DNA database for the human identity testing community

PubMed Central

Ruitberg, Christian M.; Reeder, Dennis J.; Butler, John M.

2001-01-01

The National Institute of Standards and Technology (NIST) has compiled and maintained a Short Tandem Repeat DNA Internet Database (http://www.cstl.nist.gov/biotech/strbase/) since 1997 commonly referred to as STRBase. This database is an information resource for the forensic DNA typing community with details on commonly used short tandem repeat (STR) DNA markers. STRBase consolidates and organizes the abundant literature on this subject to facilitate on-going efforts in DNA typing. Observed alleles and annotated sequence for each STR locus are described along with a review of STR analysis technologies. Additionally, commercially available STR multiplex kits are described, published polymerase chain reaction (PCR) primer sequences are reported, and validation studies conducted by a number of forensic laboratories are listed. To supplement the technical information, addresses for scientists and hyperlinks to organizations working in this area are available, along with the comprehensive reference list of over 1300 publications on STRs used for DNA typing purposes. PMID:11125125

[Retroperitoneal lymphadenectomy and survival of patients treated for an advanced ovarian cancer: the CARACO trial].

PubMed

Classe, J-M; Cerato, E; Boursier, C; Dauplat, J; Pomel, C; Villet, R; Cuisenier, J; Lorimier, G; Rodier, J-F; Mathevet, P; Houvenaeghel, G; Leveque, J; Lécuru, F

2011-05-01

The standard management for advanced-stage epithelial ovarian cancer is optimum cytoreductive surgery followed by platinum based chemotherapy. However, retroperitoneal lymph node resection remains controversial. The multiple directions of the lymph drainage pathway in ovarian cancer have been recognized. The incidence and pattern of lymph node involvement depends on the extent of the disease and the histological type. Several published cohorts suggest the survival benefit of pelvic and para-aortic lymphadenectomy. A recent large randomized trial have demonstrated the potential benefit for surgical removal of bulky lymph nodes in term of progression-free survival but failed to show any overall survival benefit because of a critical methodology. Further randomised trials are needed to balance risks and benefits of systematic lymphadenectomy in advanced-stage disease. CARACO is a French ongoing trial, built to bring a reply to this important question. A huge effort for inclusion of the patients, and involving new teams, are mandatory. Copyright © 2011 Elsevier Masson SAS. All rights reserved.

Strategic planning with multitype libraries in the community: a model with extra funding as the main goal.

PubMed Central

Gall, C F; Miller, E G

1997-01-01

Medical libraries are discovering that ongoing collaboration in fundraising with other types of community libraries is mutually beneficial. Such partnerships may lead to joint grants, increase library visibility and access to decision makers, allow participation in community information networks, and provide leverage in additional fundraising projects. These partnerships have the potential to raise the profile of libraries. The accompanying community recognition for the parent organization may create a positive image, draw patients to the health center, and position the library and institution for future success in fundraising. Within institutions, development officers may become allies, mentors, and beneficiaries of the medical librarian's efforts. For a planned approach to community outreach with extra funding as the major objective, busy medical library administrators need guidelines. Standard participative techniques were applied to strategic planning by Indianapolis libraries to help achieve successful community outreach and to write joint statements of mission, vision, goals, and objectives. PMID:9285125

The future of blood-based biomarkers for Alzheimer’s disease

PubMed Central

Henriksen, Kim; O’Bryant, Sid E.; Hampel, Harald; Trojanowski, John Q.; Montine, Thomas J.; Jeromin, Andreas; Blennow, Kaj; Lönneborg, Anders; Wyss-Coray, Tony; Soares, Holly; Bazenet, Chantal; Sjögren, Magnus; Hu, William; Lovestone, Simon; Karsdal, Morten A.; Weiner, Michael W.

2014-01-01

Treatment of Alzheimer’s disease (AD) is significantly hampered by the lack of easily accessible biomarkers that can detect disease presence and predict disease risk reliably. Fluid biomarkers of AD currently provide indications of disease stage; however, they are not robust predictors of disease progression or treatment response, and most are measured in cerebrospinal fluid, which limits their applicability. With these aspects in mind, the aim of this article is to underscore the concerted efforts of the Blood-Based Biomarker Interest Group, an international working group of experts in the field. The points addressed include: (1) the major challenges in the development of blood-based biomarkers of AD, including patient heterogeneity, inclusion of the “right” control population, and the blood– brain barrier; (2) the need for a clear definition of the purpose of the individual markers (e.g., prognostic, diagnostic, or monitoring therapeutic efficacy); (3) a critical evaluation of the ongoing biomarker approaches; and (4) highlighting the need for standardization of preanalytical variables and analytical methodologies used by the field. PMID:23850333

Associations of High-Dose Melphalan Pharmacokinetics and Outcomes in the Setting of a Randomized Cryotherapy Trial.

PubMed

Cho, Y K; Sborov, D W; Lamprecht, M; Li, J; Wang, J; Hade, E M; Gao, Y; Tackett, K; Williams, N; Benson, D M; Efebera, Y A; Rosko, A E; Devine, S M; Poi, M; Hofmeister, C C; Phelps, M A

2017-09-01

High-dose melphalan followed by autologous stem cell transplantation remains the standard of care for eligible patients with multiple myeloma, but disease response and toxicity, including severe mucositis, varies among patients. Our randomized trial investigated duration of cryotherapy (2 and 6 h) for reduction of mucositis prevalence and severity and explored factors associated with variability in pharmacokinetics and outcomes from melphalan therapy. The results demonstrate that 2-h is at least as effective as 6-h cryotherapy in decreasing severe mucositis. From a population pharmacokinetic model, we identified that fat-free mass, hematocrit, and creatinine clearance were significant covariates, as reported previously. Furthermore, we observed the rs4240803 SLC7A5 polymorphism was significantly associated with pharmacokinetic variability, and pharmacokinetics was associated with both mucositis and neutropenia. However, melphalan exposure was not associated with progression-free or overall survival in our dataset. These findings contribute to ongoing efforts to personalize melphalan dosing in transplant patients. © 2017 American Society for Clinical Pharmacology and Therapeutics.

Unemployment, Nonstandard Employment, and Fertility: Insights From Japan's "Lost 20 Years".

PubMed

Raymo, James M; Shibata, Akihisa

2017-12-01

In this study, we examine relationships of unemployment and nonstandard employment with fertility. We focus on Japan, a country characterized by a prolonged economic downturn, significant increases in both unemployment and nonstandard employment, a strong link between marriage and childbearing, and pronounced gender differences in economic roles and opportunities. Analyses of retrospective employment, marriage, and fertility data for the period 1990-2006 indicate that changing employment circumstances for men are associated with lower levels of marriage, while changes in women's employment are associated with higher levels of marital fertility. The latter association outweighs the former, and results of counterfactual standardization analyses indicate that Japan's total fertility rate would have been 10 % to 20 % lower than the observed rate after 1995 if aggregate- and individual-level employment conditions had remained unchanged from the 1980s. We discuss the implications of these results in light of ongoing policy efforts to promote family formation and research on temporal and regional variation in men's and women's roles within the family.

Pulsating stars and the distance scale

NASA Astrophysics Data System (ADS)

Macri, Lucas

2017-09-01

I present an overview of the latest results from the SH0ES project, which obtained homogeneous Hubble Space Telescope (HST) photometry in the optical and near-infrared for ˜ 3500 and ˜ 2300 Cepheids, respectively, across 19 supernova hosts and 4 calibrators to determine the value of H0 with a total uncertainty of 2.4%. I discuss the current 3.4σ "tension" between this local measurement and predictions of H0 based on observations of the CMB and the assumption of "standard" ΛCDM. I review ongoing efforts to reach σ(H0) = 1%, including recent advances on the absolute calibration of Milky Way Cepheid period-luminosity relations (PLRs) using a novel astrometric technique with HST. Lastly, I highlight recent results from another collaboration on the development of new statistical techniques to detect, classify and phase extragalactic Miras using noisy and sparsely-sampled observations. I present preliminary Mira PLRs at various wavelengths based on the application of these techniques to a survey of M33.

Risk stratification in myelodysplastic syndromes: is there a role for gene expression profiling?

PubMed

Zeidan, Amer M; Prebet, Thomas; Saad Aldin, Ehab; Gore, Steven David

2014-04-01

Evaluation of: Pellagatti A, Benner A, Mills KI et al. Identification of gene expression-based prognostic markers in the hematopoietic stem cells of patients with myelodysplastic syndromes. J. Clin. Oncol. 31(28), 3557-3564 (2013). Patients with myelodysplastic syndromes (MDS) exhibit wide heterogeneity in clinical outcomes making accurate risk-stratification an integral part of the risk-adaptive management paradigm. Current prognostic schemes for MDS rely on clinicopathological parameters. Despite the increasing knowledge of the genetic landscape of MDS and the prognostic impact of many newly discovered molecular aberrations, none to date has been incorporated formally into the major risk models. Efforts are ongoing to use data generated from genome-wide high-throughput techniques to improve the 'individualized' outcome prediction for patients. We here discuss an important paper in which gene expression profiling (GEP) technology was applied to marrow CD34(+) cells from 125 MDS patients to generate and validate a standardized GEP-based prognostic signature.

NREL-Led Effort Results in Groundbreaking New ASTM High-Octane Fuel

Science.gov Websites

Standard | News | NREL NREL-Led Effort Results in Groundbreaking New ASTM High-Octane Fuel Standard NREL-Led Effort Results in Groundbreaking New ASTM High-Octane Fuel Standard April 7, 2017 NREL . Photo by Dennis Schroeder, NREL 20114. ASTM International recently announced the release of a new high

Attitudes towards Study Effort Response to Higher Grading Standards: Do Gender and Personality Distinctions Matter?

ERIC Educational Resources Information Center

Fallan, Lars; Opstad, Leiv

2012-01-01

The purpose of this paper is to explore how gender and personality preferences affect student attitudes towards effort response to higher grading standards. Data collected from 150 economics and business students at a Scandinavian business school reveals that higher grading standards enhance effort and time devoted to learning to a higher degree…

The Horizon Report. 2006 Edition

ERIC Educational Resources Information Center

New Media Consortium, 2006

2006-01-01

This third edition of the New Media Consortium's (NMC) annual "Horizon Report" describes the continuing work of the Horizon Project, a research-oriented effort that seeks to identify and describe emerging technologies likely to have a large impact on teaching, learning, or creative expression within higher education. Drawing on ongoing discussions…

77 FR 33212 - Notice of FERC Staff Attendance at the Entergy Regional State Committee Meeting

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-05

... Gulf States, Louisiana, LLC Docket No. ER11-2133 Entergy Gulf States, Louisiana, LLC Docket No. ER11... Entergy Regional State Committee Meeting The Federal Energy Regulatory Commission (Commission) hereby... the Commission's ongoing outreach efforts. Entergy Regional State Committee Meeting June 6, 2012-June...

Smoothing the Path to Learning Success: A Student Perspective

ERIC Educational Resources Information Center

Doucette, Colleen

2005-01-01

The education system invests time and resources in collaborative processes designed to improve its ability to support students as successful learners. Traditionally, it seeks the advice of educators, researchers, ministries and boards of education, parents, and the public at large in an ongoing effort to increase its effectiveness. Less…

Typology for Parents of Abused Children.

ERIC Educational Resources Information Center

Sloan, Michael P.; Meier, John H.

This paper reports an effort to classify parents of abused children according to existing and new typologies derived from parents' psychopathological personality profiles. Several previously reported typologies for abusive parents are reviewed and elaborated. In addition, reference is given to data and insights gained from an ongoing study of 50…

Prediction of Composition and Emission Characteristics of Articles in Support of Exposure Assessment

EPA Science Inventory

The risk to humans from chemicals in consumer products is dependent on both hazard and exposure. The prediction and quantification of near-field (i.e., indoor) chemical exposure from household articles such as furniture and building materials is an ongoing effort. As opposed to (...

The California Basic Skills Initiative

ERIC Educational Resources Information Center

Illowsky, Barbara

2008-01-01

This article describes the evolution and implementation of the California Basic Skills Initiative (CA BSI), a statewide effort to address ongoing basic skills and ESL needs of community college students and of all campus faculty, administrators, and staff who support these students. CA BSI strategies include assisting every college in assessing…

Nondestructive testing and evaluation of wood : a worldwide research update

Treesearch

Brian K. Brashaw; Voichita Bucur; Ferenc Divos; Raquel Goncalves; Jianxiong Lu; Roger Meder; Roy F. Pellerin; Simon Potter; Robert J Ross; Xiping Wang; Yafang Yin

2009-01-01

The international forest products research community is responding to these driving forces by conducting NDT/NDE research to provide the technologies needed to address these challenges. This article presents a sample of the on-going NDT/NDE research efforts being conducted in several areas of the world.

Photographic Data Extraction Feasibility and Pilot Study in Support of Roadside Safety and Roadway Departure Research

DOT National Transportation Integrated Search

2014-05-01

This work represents the first phase of an ongoing low-cost in-house effort to perform data analysis, optimize internal data gathering in an informed fashion, make data requests to organizations, and obtain needed information. The work also calls on ...

Polymer Day: Outreach Experiments for High School Students

ERIC Educational Resources Information Center

Ting, Jeffrey M.; Ricarte, Ralm G.; Schneiderman, Deborah K.; Saba, Stacey A.; Jiang, Yaming; Hillmyer, Marc A.; Bates, Frank S.; Reineke, Theresa M.; Macosko, Christopher W.; Lodge, Timothy P.

2017-01-01

We present a collection of hands-on experiments that collectively teach precollege students fundamental concepts of polymer synthesis and characterization. These interactive experiments are performed annually as part of an all-day outreach event for high school students that can inform the development of ongoing polymer education efforts in a…

The NMC Horizon Report: 2013 K-12 Edition

ERIC Educational Resources Information Center

Johnson, L.; Adams Becker, S.; Cummins, M.; Estrada V.; Freeman, A.; Ludgate, H.

2013-01-01

"The NMC Horizon Report" series is the most visible outcome of the New Media Consortium (NMC) Horizon Project, an ongoing research effort established in 2002 that identifies and describes emerging technologies likely to have a large impact on teaching, learning, research, or creative expression within education around the globe. This…

Insight and Action Analytics: Three Case Studies to Consider

ERIC Educational Resources Information Center

Milliron, Mark David; Malcolm, Laura; Kil, David

2014-01-01

Civitas Learning was conceived as a community of practice, bringing together forward-thinking leaders from diverse higher education institutions to leverage insight and action analytics in their ongoing efforts to help students learn well and finish strong. We define insight and action analytics as drawing, federating, and analyzing data from…

Homegrown Internationalization: Local Language Diversity as a Resource for Global Educational Initiatives

ERIC Educational Resources Information Center

Crutchfield, Anne

2016-01-01

This case study explored internationalization, diversity, and language through the eyes of students, instructors, and administrators at a multicultural community college in Hawai'i. The purpose was to uncover participants' beliefs and attitudes about ongoing campus-wide internationalization efforts as well as to investigate their broader…

Systematically evaluating read-across prediction and performance using a local validity approach characterized by chemical structure and bioactivity information

EPA Science Inventory

Read-across is a popular data gap filling technique within category and analogue approaches for regulatory purposes. Acceptance of read-across remains an ongoing challenge with several efforts underway for identifying and addressing uncertainties. Here we demonstrate an algorithm...

Premature mortality in the U.S.-- trends by race, ethnicity, age, and region

Cancer.gov

DCEG scientists are spearheading the Premature Mortality Project—an interdisciplinary, multi-institutional effort to characterize U.S. trends in premature mortality. In the process, the team has uncovered distinct mortality trends by race, ethnicity, age, and region, and provided crucial information about the ongoing,

Integration of Fall Prevention into State Policy in Connecticut

ERIC Educational Resources Information Center

Murphy, Terrence E.; Baker, Dorothy I.; Leo-Summers, Linda S.; Bianco, Luann; Gottschalk, Margaret; Acampora, Denise; King, Mary B.

2013-01-01

Purpose of Study: To describe the ongoing efforts of the Connecticut Collaboration for Fall Prevention (CCFP) to move evidence regarding fall prevention into clinical practice and state policy. Methods: A university-based team developed methods of networking with existing statewide organizations to influence clinical practice and state policy.…

Horizon Report: 2010 K-12 Edition

ERIC Educational Resources Information Center

Johnson, L.; Smith, R.; Levine, A.; Haywood, K.

2010-01-01

The "Horizon Report" series is the most visible outcome of the New Media Consortium's Horizon Project, an ongoing research effort established in 2002 that identifies and describes emerging technologies likely to have a large impact on teaching, learning, research, or creative expression within education around the globe. This volume, the "2010…

45 CFR 2516.810 - What types of evaluations are grantees and subgrantees required to perform?

Code of Federal Regulations, 2010 CFR

2010-10-01

... Welfare (Continued) CORPORATION FOR NATIONAL AND COMMUNITY SERVICE SCHOOL-BASED SERVICE-LEARNING PROGRAMS...? All grantees and subgrantees are required to perform internal evaluations which are ongoing efforts to assess performance and improve quality. Grantees and subgrantees may, but are not required to, arrange...

Implications of NCLB Accountability for Comprehensive School Reform

ERIC Educational Resources Information Center

Le Floch, Kerstin Carlson; Taylor, James E.; Thomsen, Kerri

2006-01-01

No Child Left Behind (NCLB) accountability mechanisms have the potential to derail comprehensive school reform (CSR) implementation. For those pursuing CSR, the question is how to reconcile the implementation of NCLB accountability mandates with ongoing CSR efforts. Drawing from longitudinal data from a national study of CSR, this article explores…

Using Facebook to Support Novice Teachers

ERIC Educational Resources Information Center

Staudt, Denise; St. Clair, Norman; Martinez, Elda E.

2013-01-01

Providing quality support for novice teachers as they enter the profession has been an ongoing concern of educator preparation programs. This article describes the efforts of one teacher preparation program in addressing this matter by utilizing Facebook[R] to provide sustained support and professional development for its beginning teachers. We…

Using Demographics and Statistics To Inform Target Audiences.

ERIC Educational Resources Information Center

Hastings, Janel Henriksen

2000-01-01

Reviews literature that explores the changing role of institutional research in community colleges and its increasing involvement in marketing and institutional advancement activities in two-year colleges. Describes ongoing efforts at a community college in Chicago to identify media resources used most frequently by students, and discusses how the…

The Horizon Report. 2004 Edition

ERIC Educational Resources Information Center

New Media Consortium, 2004

2004-01-01

This first edition of the New Media Consortium's (NMC) annual "Horizon Report" details findings of the Horizon Project, a research-oriented effort that seeks to identify and describe emerging technologies likely to have a large impact on teaching, learning, or creative expression within higher education. Drawing on an ongoing series of interviews…

Key Emerging Technologies for Elementary and Secondary Education

ERIC Educational Resources Information Center

Johnson, Laurence F.; Levine, Alan; Smith, Rachel S.; Haywood, Keene

2010-01-01

The Horizon Report series is the most visible outcome of the New Media Consortium's Horizon Project, an ongoing research effort that identifies and describes emerging technologies likely to have a large impact on teaching, learning, research, or creative expression within education around the globe. The report examines emerging technologies for…

Key Emerging Technologies for Elementary and Secondary Education

ERIC Educational Resources Information Center

Johnson, Laurence F.; Levine, Alan; Smith, Rachel S.; Haywood, Keene

2010-01-01

The "Horizon Report" series is the most visible outcome of the New Media Consortium's Horizon Project, an ongoing research effort that identifies and describes emerging technologies likely to have a large impact on teaching, learning, research, or creative expression within education around the globe. The report examines emerging technologies for…

Fans: An Integral Element of the Green Learning Environment

ERIC Educational Resources Information Center

Wolgelenter, Nina

2011-01-01

School districts' ongoing efforts to promote sustainability in America's education facilities are helping raise awareness of social responsibility and promoting the positive effects that greening their learning environments has on the general health and productivity of students. One institution that's taking the lead in this movement is Chandler…

WATERSHED CHARACTERISTICS AND PRE-RESTORATION SURFACE-WATER HYDROLOGY OF MINEBANK RUN, BALTIMORE COUNTY, MARYLAND, WATER YEARS 2002-04

EPA Science Inventory

Stream restoration efforts have been ongoing in Maryland since the early 1990s. Physical stream restoration often involves replacement of lost sediments to elevate degraded streambeds, re-establishment of riffle-pool sequences along the channel profile, planting vegetation in rip...

76 FR 62804 - Notice of FERC Staff Attendance at the Entergy Regional State Committee Work Group and...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-11

... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Notice of FERC Staff Attendance at the Entergy Regional State Committee Work Group and Stakeholder Meeting The Federal Energy Regulatory... is part of the Commission's ongoing outreach efforts. Entergy Regional State Committee Work Group and...

Selected Syllabi for Infusing Career Education into College and University Courses.

ERIC Educational Resources Information Center

Dunbar, Zola, Ed.

The infusion of career education concepts into college and university courses is documented by this collection of twenty college course syllabi developed to facilitate the ongoing efforts of Oregon's colleges and universities in preparing educational personnel for the development and conduct of career education activities. These twenty syllabi…

Building Inclusive Engineering Identities: Implications for Changing Engineering Culture

ERIC Educational Resources Information Center

Atadero, Rebecca A.; Paguyo, Christina H.; Rambo-Hernandez, Karen E.; Henderson, Heather L.

2018-01-01

Ongoing efforts to broaden the participation of women and people of colour in engineering degree programmes and careers have had limited success. This paper describes a different approach to broadening participation that seeks to work with all students and develop inclusive engineering identities. Researchers worked with the instructors of two…

Urban pedestrian accident countermeasures experimental evaluation. Volume 2 Appendix A, Review of education and public information materials

DOT National Transportation Integrated Search

1975-02-01

This technical appendix presents an overview of the national pedestrian safety effort. The appendix also reports the results of a survey of 48 ongoing educational programs being conducted in eight U.S. urban centers. A final chapter suggests procedur...

76 FR 60385 - Privacy Act of 1974: Implementation of Exemptions; Department of Homeland Security U.S...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-29

... for Disclosures) because release of the accounting of disclosures could alert the subject of an... efforts to preserve national security. Disclosure of the accounting would also permit the individual who... ongoing law enforcement, national security or fraud investigation; to avoid disclosure of investigative...

Strategies for monitoring terrestrial animals and habitats

Treesearch

Richard Holthausen; Raymond L. Czaplewski; Don DeLorenzo; Greg Hayward; Winifred B. Kessler; Pat Manley; Kevin S. McKelvey; Douglas S. Powell; Leonard F. Ruggiero; Michael K. Schwartz; Bea Van Horne; Christina D. Vojta

2005-01-01

This General Technical Report (GTR) addresses monitoring strategies for terrestrial animals and habitats. It focuses on monitoring associated with National Forest Management Act planning and is intended to apply primarily to monitoring efforts that are broader than individual National Forests. Primary topics covered in the GTR are monitoring requirements; ongoing...

(Re)constructing Ideals of Multicultural Education through "Grow Your Own Teachers"

ERIC Educational Resources Information Center

Madda, Christina L.; Schultz, Brian D.

2009-01-01

Reflecting on the current status of multicultural education in higher education institutions, we examine "Grow Your Own Teachers," a progressive, innovative program that not only embodies and enacts major principles of multicultural education, but also represents an ongoing effort to redefine and revitalize multicultural education within…

The Research Funding Guidebook: Getting It, Managing It, and Renewing It.

ERIC Educational Resources Information Center

Ries, Joanne B.; Leukefeld, Carl G.

This guide, intended primarily for new or inexperienced researchers, provides suggestions for obtaining and maintaining external funding from grants and contracts. It emphasizes that this effort requires considerable thought, ongoing planning, sound management, and clear decisions. The book uses the National Institutes of Health application and…

Developing a Successful Asynchronous Online Extension Program for Forest Landowners

ERIC Educational Resources Information Center

Zobrist, Kevin W.

2014-01-01

Asynchronous online Extension classes can reach a wide audience, is convenient for the learner, and minimizes ongoing demands on instructor time. However, producing such classes takes significant effort up front. Advance planning and good communication with contributors are essential to success. Considerations include delivery platforms, content…

Common Ground: A Way of Life, Not a Checkoff Item.

ERIC Educational Resources Information Center

Ledell, Marjorie A.

1996-01-01

The common ground process is an ongoing effort for inviting, scrutinizing, debating, and selecting ideas or making decisions about improving schools. Superintendents should assign a full-time communications person to executive staff, create a communications team, conduct a full-scale communications audit, listen better, urge the silent majority to…

28 CFR 16.132 - Exemption of Department of Justice System-Personnel Investigation and Security Clearance Records...

Code of Federal Regulations, 2010 CFR

2010-07-01

...) Subsection (d)(2). Amendment of the records could interfere with ongoing criminal or civil law enforcement... actual or potential law enforcement or counterintelligence investigation, and thereby seriously impede law enforcement or counterintelligence efforts by permitting the record subject and other persons to...

28 CFR 16.132 - Exemption of Department of Justice System-Personnel Investigation and Security Clearance Records...

Code of Federal Regulations, 2012 CFR

2012-07-01

...) Subsection (d)(2). Amendment of the records could interfere with ongoing criminal or civil law enforcement... actual or potential law enforcement or counterintelligence investigation, and thereby seriously impede law enforcement or counterintelligence efforts by permitting the record subject and other persons to...

28 CFR 16.132 - Exemption of Department of Justice System-Personnel Investigation and Security Clearance Records...

Code of Federal Regulations, 2011 CFR

2011-07-01

...) Subsection (d)(2). Amendment of the records could interfere with ongoing criminal or civil law enforcement... actual or potential law enforcement or counterintelligence investigation, and thereby seriously impede law enforcement or counterintelligence efforts by permitting the record subject and other persons to...

28 CFR 16.132 - Exemption of Department of Justice System-Personnel Investigation and Security Clearance Records...

Code of Federal Regulations, 2014 CFR

2014-07-01

...) Subsection (d)(2). Amendment of the records could interfere with ongoing criminal or civil law enforcement... actual or potential law enforcement or counterintelligence investigation, and thereby seriously impede law enforcement or counterintelligence efforts by permitting the record subject and other persons to...

28 CFR 16.132 - Exemption of Department of Justice System-Personnel Investigation and Security Clearance Records...

Code of Federal Regulations, 2013 CFR

2013-07-01

...) Subsection (d)(2). Amendment of the records could interfere with ongoing criminal or civil law enforcement... actual or potential law enforcement or counterintelligence investigation, and thereby seriously impede law enforcement or counterintelligence efforts by permitting the record subject and other persons to...

Lessons Learned: The Evolution of an Undergraduate Research Program

ERIC Educational Resources Information Center

Smith, Gregory; Laker, Lauren; Tesch, Debbie

2013-01-01

Undergraduate research programs are commonplace at many universities. However, little research has been conducted to evaluate their ongoing and long-term effectiveness from the standpoint of the undergraduate student researcher. In an effort to gain perspective from the student researcher, including their thoughts on such a program, a survey was…

77 FR 55429 - Fitness-for-Duty Programs

Federal Register 2010, 2011, 2012, 2013, 2014

2012-09-10

...-2009-0090] RIN 3150-AI58 Fitness-for-Duty Programs AGENCY: Nuclear Regulatory Commission. ACTION... ongoing proposed rulemaking effort to amend its regulations regarding Fitness-for-Duty Programs. The NRC... portions of part 26 of Title 10 of the Code of Federal Regulations (10 CFR), ``Fitness-for-Duty Programs...

SOME QUANTITATIVE ASPECTS OF THE INSTRUCTIONAL PROCESS.

ERIC Educational Resources Information Center

GAVIN, WILLIAM J.; SPITZER, MURRAY

THE DATA FROM THE SEVERAL STUDIES ANALYZED IN THIS REPORT HAVE BEEN COLLECTED AS PART OF AN ON-GOING EFFORT TO IMPLEMENT THE ABT ASSOCIATES' EDUCATION COST EFFECTIVENESS INSTRUCTIONAL PROCESS SUBMODEL, WHICH IS DEVELOPING TECHNIQUES TO EVALUATE THE QUANTITATIVE, CAUSE-AND-EFFECT RELATIONSHIP BETWEEN THE INSTRUCTIONAL PROCESS AND SCHOLASTIC…

The Horizon Report. 2005 Edition

ERIC Educational Resources Information Center

New Media Consortium, 2005

2005-01-01

This second edition of the New Media Consortium's (NMC) annual "Horizon Report" describes the continuing work of the Horizon Project, a research-oriented effort that seeks to identify and describe emerging technologies likely to have a large impact on teaching, learning, or creative expression within higher education. Drawing on an ongoing series…

Transcriptome assembly, gene annotation and tissue gene expression atlas of the rainbow trout

USDA-ARS?s Scientific Manuscript database

Efforts to obtain a comprehensive genome sequence for rainbow trout are ongoing and will be complimented by transcriptome information that will enhance genome assembly and annotation. Previously, we reported a transcriptome reference sequence using a 19X coverage of Sanger and 454-pyrosequencing dat...

Ensuring the Ongoing Engagement of Second-Stage Teachers

ERIC Educational Resources Information Center

Kirkpatrick, Cheryl L.; Johnson, Susan Moore

2014-01-01

Research and policy have increasingly focused on the importance of staffing schools with effective teachers. A critical variable affecting teacher effectiveness is the enthusiasm, energy and effort teachers bring to their work, or teachers' work engagement. Better understanding teachers' work engagement and how it may change over stages…

Trailblazing Partnerships: Professional Development Schools in Partnership with Emporia State University

ERIC Educational Resources Information Center

Jones, Jill; Schwerdtfeger, Sara; Roop, Teddy; Long, Jennie L.

2016-01-01

Emporia State University is committed to preparing future elementary education teachers through the collaborative efforts and ongoing reflective practice between the university and school districts. The Professional Development School is the vehicle behind the structured involvement in the process of immersing student-teacher in a clinical model…

The Offshore Model for Universities

ERIC Educational Resources Information Center

Ross, Andrew

2008-01-01

This article discusses the ongoing effort of the World Trade Organization (WTO) to bring higher education services within the purview of the General Agreement on Trade and Services (GATS). One result of the anticipated liberalization of trade in education, the author explains, is the headlong rush of Anglophone universities into the global market…

Socio-Economic Impact Assessment of the Computerized Customer Information System (CCIS) at the Southern California Rapid Transit District (SCRTD)

DOT National Transportation Integrated Search

1983-06-01

This document is a product of an ongoing program to assess the impacts of automated transit information system (ATIS) technology on the transit industry's efforts to improve the productivity and quality of telephone information/marketing services to ...

The NMC Horizon Report: 2015 Higher Education Edition

ERIC Educational Resources Information Center

Johnson, L.; Adams Becker, S.; Estrada, V.; Freeman, A.

2015-01-01

The "NMC Horizon Report: 2015 Higher Education Edition" is a collaborative effort between the New Media Consortium (NMC) and the EDUCAUSE Learning Initiative (ELI). This 12th edition describes annual findings from the NMC Horizon Project, an ongoing research project designed to identify and describe emerging technologies likely to have…

The Strategic Assessment Model.

ERIC Educational Resources Information Center

Glazner, Steve, Ed.

This book presents six papers focusing on the application of the strategic assessment model (SAM) to the management of higher education facilities. The papers are part of an ongoing effort by the Association of Higher Education Facilities Officers to provide comparative cost and staffing information and to develop a benchmarking process. The…

Community Organizing: Strategies for Recruitment and Retention.

ERIC Educational Resources Information Center

Reyes, Reva Crawford

This book summarizes the role of community organizing principles in a successful adult education program serving Native American adults. Gleaned from workshops conducted by two Cherokees who have been highly successful in their own community organizing efforts, from ongoing staff discussion, and from years of practical experiences of program…

EVALUATION OF THE LEVELS OF DIOXIN-LIKE COMPOUNDS IN ANIMAL FEEDS

EPA Science Inventory

The purpose of this study is to measure the levels of dioxin-like compounds in the feeds of terrestrial food animals - cattle, swine, and poultry - and to understand their contribution to the dioxin-like levels found in the animals. It is an ongoing effort involving several phase...

76 FR 65191 - California Independent System Operator Corporation; Notice of FERC Staff Attendance

Federal Register 2010, 2011, 2012, 2013, 2014

2011-10-20

...; Notice of FERC Staff Attendance The Federal Energy Regulatory Commission (Commission) hereby gives notice that on the following dates members of its staff will participate in teleconferences and meetings to be... staff's attendance is part of the Commission's ongoing outreach efforts. The teleconferences and...

28 CFR 91.58 - Timing of the environmental review process.

Code of Federal Regulations, 2010 CFR

2010-07-01

... decisions or new commitments of resources can be made on these projects by the State or local entity that... specifications; or (5) Purchasing property. (e) Ongoing or completed construction projects. For grant-funded... been done, making every effort to limit disruption to projects under construction. For completed grant...

Train-to-Train Impact Test of Crash-Energy Management Passenger Rail Equipment: Occupant Experiments

DOT National Transportation Integrated Search

2006-11-06

As part of an ongoing passenger rail crashworthiness effort, : a full-scale impact test of a train with crash energy management : (CEM) passenger cars was conducted on March 23, 2006. In : this test, a train made up of a CEM cab car, four CEM coach :...

Trophic Structure Over the Northern Mid-Atlantic Ridge: The Bathypelagic Zone Really Matters

EPA Science Inventory

We present preliminary results and ongoing efforts to characterize the trophic structure and energy flow of the pelagic ecosystems of the northern Mid-Atlantic Ridge (MAR), from Iceland to the Azores. This study is one component of the international CoML field project MAR-ECO (ww...

Restorative Justice: Pedagogy, Praxis, and Discipline

ERIC Educational Resources Information Center

Morrison, Brenda E.; Vaandering, Dorothy

2012-01-01

In the ongoing effort of designing school contexts in support of proactive discipline, a range of practices and theoretical frameworks have been advanced, from behaviorist approaches to social and emotional learning. This article describes the theory and practice of restorative justice with the aim of defining this distinctive paradigm, in…

Final Report of the Mid-Atlantic Marine Wildlife Surveys, Modeling, and Data

DOE Office of Scientific and Technical Information (OSTI.GOV)

Saracino-Brown, Jocelyn; Smith, Courtney; Gilman, Patrick

The Wind Program hosted a two-day workshop on July 24-25, 2012 with scientists and regulators engaged in marine ecological survey, modeling, and database efforts pertaining to the waters of the Mid-Atlantic region. The workshop was planned by Federal agency, academic, and private partners to promote collaboration between ongoing offshore ecological survey efforts, and to promote the collaborative development of complementary predictive models and compatible databases. The meeting primarily focused on efforts to establish and predict marine mammal, seabird, and sea turtle abundance, density, and distributions extending from the shoreline to the edge of the Exclusive Economic Zone between Nantucket Sound,more » Massachusetts and Cape Hatteras, North Carolina.« less

Final report, on-going key comparison BIPM.QM-K1, ozone at ambient level, comparison with NIST, July 2015

NASA Astrophysics Data System (ADS)

Viallon, Joële; Moussay, Philippe; Wielgosz, Robert; Hodges, Joe; Norris, James E.

2017-01-01

As part of the ongoing key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of the National Institute of Standards and Technology (NIST) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM). The instruments have been compared over a nominal ozone amount-of-substance fraction range of 0 nmol/mol to 500 nmol/mol. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Year 3 of Implementing the Common Core State Standards: Professional Development for Teachers and Principals

ERIC Educational Resources Information Center

Kober, Nancy; McIntosh, Shelby; Rentner, Diane Stark

2013-01-01

Timely, ongoing, and effective professional development for teachers and principals will be critical to the successful implementation of the Common Core State Standards (CCSS). These voluntary state-developed standards in mathematics and English language arts (ELA) outline the knowledge and skills that students in grades kindergarten through 12…

The PLAID graphics analysis impact on the space program

NASA Technical Reports Server (NTRS)

Nguyen, Jennifer P.; Wheaton, Aneice L.; Maida, James C.

1994-01-01

An ongoing project design often requires visual verification at various stages. These requirements are critically important because the subsequent phases of that project might depend on the complete verification of a particular stage. Currently, there are several software packages at JSC that provide such simulation capabilities. We present the simulation capabilities of the PLAID modeling system used in the Flight Crew Support Division for human factors analyses. We summarize some ongoing studies in kinematics, lighting, EVA activities, and discuss various applications in the mission planning of the current Space Shuttle flights and the assembly sequence of the Space Station Freedom with emphasis on the redesign effort.

Second generation registry framework.

PubMed

Bellgard, Matthew I; Render, Lee; Radochonski, Maciej; Hunter, Adam

2014-01-01

Information management systems are essential to capture data be it for public health and human disease, sustainable agriculture, or plant and animal biosecurity. In public health, the term patient registry is often used to describe information management systems that are used to record and track phenotypic data of patients. Appropriate design, implementation and deployment of patient registries enables rapid decision making and ongoing data mining ultimately leading to improved patient outcomes. A major bottleneck encountered is the static nature of these registries. That is, software developers are required to work with stakeholders to determine requirements, design the system, implement the required data fields and functionality for each patient registry. Additionally, software developer time is required for ongoing maintenance and customisation. It is desirable to deploy a sophisticated registry framework that can allow scientists and registry curators possessing standard computing skills to dynamically construct a complete patient registry from scratch and customise it for their specific needs with little or no need to engage a software developer at any stage. This paper introduces our second generation open source registry framework which builds on our previous rare disease registry framework (RDRF). This second generation RDRF is a new approach as it empowers registry administrators to construct one or more patient registries without software developer effort. New data elements for a diverse range of phenotypic and genotypic measurements can be defined at any time. Defined data elements can then be utilised in any of the created registries. Fine grained, multi-level user and workgroup access can be applied to each data element to ensure appropriate access and data privacy. We introduce the concept of derived data elements to assist the data element standards communities on how they might be best categorised. We introduce the second generation RDRF that enables the user-driven dynamic creation of patient registries. We believe this second generation RDRF is a novel approach to patient registry design, implementation and deployment and a significant advance on existing registry systems.

Second generation registry framework

PubMed Central

2014-01-01

Background Information management systems are essential to capture data be it for public health and human disease, sustainable agriculture, or plant and animal biosecurity. In public health, the term patient registry is often used to describe information management systems that are used to record and track phenotypic data of patients. Appropriate design, implementation and deployment of patient registries enables rapid decision making and ongoing data mining ultimately leading to improved patient outcomes. A major bottleneck encountered is the static nature of these registries. That is, software developers are required to work with stakeholders to determine requirements, design the system, implement the required data fields and functionality for each patient registry. Additionally, software developer time is required for ongoing maintenance and customisation. It is desirable to deploy a sophisticated registry framework that can allow scientists and registry curators possessing standard computing skills to dynamically construct a complete patient registry from scratch and customise it for their specific needs with little or no need to engage a software developer at any stage. Results This paper introduces our second generation open source registry framework which builds on our previous rare disease registry framework (RDRF). This second generation RDRF is a new approach as it empowers registry administrators to construct one or more patient registries without software developer effort. New data elements for a diverse range of phenotypic and genotypic measurements can be defined at any time. Defined data elements can then be utilised in any of the created registries. Fine grained, multi-level user and workgroup access can be applied to each data element to ensure appropriate access and data privacy. We introduce the concept of derived data elements to assist the data element standards communities on how they might be best categorised. Conclusions We introduce the second generation RDRF that enables the user-driven dynamic creation of patient registries. We believe this second generation RDRF is a novel approach to patient registry design, implementation and deployment and a significant advance on existing registry systems. PMID:24982690

Westinghouse programs in pulsed homopolar power supplies

NASA Technical Reports Server (NTRS)

Litz, D. C.; Mullan, E.

1984-01-01

This document details Westinghouse's ongoing study of homopolar machines since 1929 with the major effort occurring in the early 1970's to the present. The effort has enabled Westinghouse to develop expertise in the technology required for the design, fabrication and testing of such machines. This includes electrical design, electromagnetic analysis, current collection, mechanical design, advanced cooling, stress analysis, transient rotor performance, bearing analysis and seal technology. Westinghouse is using this capability to explore the use of homopolar machines as pulsed power supplies for future systems in both military and commercial applications.

Employment of individuals in the Social Security disability programs.

PubMed

O'Leary, Paul; Livermore, Gina A; Stapleton, David C

2011-01-01

The articles in this special issue present findings from research on the employment and work-related activities of individuals receiving benefits through the Social Security Disability Insurance and Supplemental Security Income programs, and on the factors that hinder their efforts to work at levels that lead to exiting the disability rolls. This article introduces the other articles, highlights their important findings, and discusses the implications for ongoing efforts to increase the earnings and self-sufficiency of these beneficiaries, such as the Ticket to Work program and the Benefit Offset National Demonstration.

Space Station Environmental Control and Life Support Systems: An Update on Waste Water Reclamation

NASA Technical Reports Server (NTRS)

Ferner, Kathleen M.

1994-01-01

Since the mid-1980's, work has been ongoing In the development of the various environmental control and life support systems (ECLSS) for the space station. Part of this effort has been focused on the development of a new subsystem to reclaim waste water that had not been previously required for shuttle missions. Because of the extended manned missions proposed, reclamation of waste water becomes imperative to avoid the weight penalties associated with resupplying a crew's entire water needs for consumption and daily hygiene. Hamilton Standard, under contract to Boeing Aerospace and Electronics, has been designing the water reclamation system for space station use. Since June of 1991, Hamilton Standard has developed a combined water processor capable of reclaiming potable quality water from waste hygiene water, used laundry water, processed urine, Shuttle fuel cell water, humidity condensate and other minor waste water sources. The system was assembled and then tested with over 27,700 pounds of 'real' waste water. During the 1700 hours of system operation required to process this waste water, potable quality water meeting NASA and Boeing specifications was produced. This paper gives a schematic overview of the system, describes the test conditions and test results and outlines the next steps for system development.

Future Long-Baseline Neutrino Facilities and Detectors

DOE PAGES

Diwan, Milind; Edgecock, Rob; Hasegawa, Takuya; ...

2013-01-01

We review the ongoing effort in the US, Japan, and Europe of the scientific community to study the location and the detector performance of the next-generation long-baseline neutrino facility. For many decades, research on the properties of neutrinos and the use of neutrinos to study the fundamental building blocks of matter has unveiled new, unexpected laws of nature. Results of neutrino experiments have triggered a tremendous amount of development in theory: theories beyond the standard model or at least extensions of it and development of the standard solar model and modeling of supernova explosions as well as the development ofmore » theories to explain the matter-antimatter asymmetry in the universe. Neutrino physics is one of the most dynamic and exciting fields of research in fundamental particle physics and astrophysics. The next-generation neutrino detector will address two aspects: fundamental properties of the neutrino like mass hierarchy, mixing angles, and the CP phase, and low-energy neutrino astronomy with solar, atmospheric, and supernova neutrinos. Such a new detector naturally allows for major improvements in the search for nucleon decay. A next-generation neutrino observatory needs a huge, megaton scale detector which in turn has to be installed in a new, international underground laboratory, capable of hosting such a huge detector.« less

Informatics in radiology: Efficiency metrics for imaging device productivity.

PubMed

Hu, Mengqi; Pavlicek, William; Liu, Patrick T; Zhang, Muhong; Langer, Steve G; Wang, Shanshan; Place, Vicki; Miranda, Rafael; Wu, Teresa Tong

2011-01-01

Acute awareness of the costs associated with medical imaging equipment is an ever-present aspect of the current healthcare debate. However, the monitoring of productivity associated with expensive imaging devices is likely to be labor intensive, relies on summary statistics, and lacks accepted and standardized benchmarks of efficiency. In the context of the general Six Sigma DMAIC (design, measure, analyze, improve, and control) process, a World Wide Web-based productivity tool called the Imaging Exam Time Monitor was developed to accurately and remotely monitor imaging efficiency with use of Digital Imaging and Communications in Medicine (DICOM) combined with a picture archiving and communication system. Five device efficiency metrics-examination duration, table utilization, interpatient time, appointment interval time, and interseries time-were derived from DICOM values. These metrics allow the standardized measurement of productivity, to facilitate the comparative evaluation of imaging equipment use and ongoing efforts to improve efficiency. A relational database was constructed to store patient imaging data, along with device- and examination-related data. The database provides full access to ad hoc queries and can automatically generate detailed reports for administrative and business use, thereby allowing staff to monitor data for trends and to better identify possible changes that could lead to improved productivity and reduced costs in association with imaging services. © RSNA, 2011.

Advanced magnetic resonance imaging in glioblastoma: a review.

PubMed

Shukla, Gaurav; Alexander, Gregory S; Bakas, Spyridon; Nikam, Rahul; Talekar, Kiran; Palmer, Joshua D; Shi, Wenyin

2017-08-01

Glioblastoma, the most common and most rapidly progressing primary malignant tumor of the central nervous system, continues to portend a dismal prognosis, despite improvements in diagnostic and therapeutic strategies over the last 20 years. The standard of care radiographic characterization of glioblastoma is magnetic resonance imaging (MRI), which is a widely utilized examination in the diagnosis and post-treatment management of patients with glioblastoma. Basic MRI modalities available from any clinical scanner, including native T1-weighted (T1w) and contrast-enhanced (T1CE), T2-weighted (T2w), and T2-fluid-attenuated inversion recovery (T2-FLAIR) sequences, provide critical clinical information about various processes in the tumor environment. In the last decade, advanced MRI modalities are increasingly utilized to further characterize glioblastomas more comprehensively. These include multi-parametric MRI sequences, such as dynamic susceptibility contrast (DSC), dynamic contrast enhancement (DCE), higher order diffusion techniques such as diffusion tensor imaging (DTI), and MR spectroscopy (MRS). Significant efforts are ongoing to implement these advanced imaging modalities into improved clinical workflows and personalized therapy approaches. Functional MRI (fMRI) and tractography are increasingly being used to identify eloquent cortices and important tracts to minimize postsurgical neuro-deficits. A contemporary review of the application of standard and advanced MRI in clinical neuro-oncologic practice is presented here.

UO 2 Particle Standards: Synthesis, Purification & Planchet Preparation

DOE Office of Scientific and Technical Information (OSTI.GOV)

Barrett, Christopher A.; Anheier, Norman C.

2016-03-31

The IAEA has previously indicated its desire for reliable provision of suitable reference materials in support of environmental sample analysis and sustained advancement at the Department of Safeguards, as laid out in the Long Term R&D plan (LTRD 10.1 & 10.2). In a recent meeting between NPAC, the IAEA and PNNL, this pressing need was directly outlined by the IAEA as having two main objectives. The first pertains to current operations, such as instrument calibrations and evaluation of bias across the Network of Analytical Laboratories and requires particles on the order of 300-500 nm in diameter. The second need formore » particle reference material would directly support the IAEA’s ongoing R&D efforts and calls for smaller particles ranging from 50 -100 nm in size. As such, the IAEA has expressed a great deal of interest in the newly established synthesis capabilities at PNNL, initially cultivated through a PNNL LDRD project to address the particle-standards shortcomings for uranium oxide material. The joint meeting concluded with a request by the IAEA for 1-2 planchet samples containing PNNL’s UO 2 particulate material, to be delivered in the near-term. This report outlines the steps taken to meet that request and includes some basic characteristics of the samples sent to the IAEA.« less

Final report, on-going key comparison BIPM.QM-K1, ozone at ambient level, comparison with NMISA, June 2017

NASA Astrophysics Data System (ADS)

Viallon, Joële; Idrees, Faraz; Moussay, Philippe; Wielgosz, Robert; Ntsasa, Napo G.; Tshilongo, James; Mphaphuli, Gumani E.; Norris, James E.; Hodges, Joseph T.

2018-01-01

As part of the on-going key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of South Africa maintained by the National Metrology Institute of South Africa (NMISA) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM), via a transfer standard maintained by the National Institute of Standards and Technology (NIST). The instruments have been compared over a nominal ozone amount-of-substance fraction range of 0 nmol/mol to 500 nmol/mol. Main text To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/. The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).

Gravitational waves in axion inflation: implications for CMB and small-scales interferometer measurements

NASA Astrophysics Data System (ADS)

Unal, Caner; Peloso, Marco; Sorbo, Lorenzo; Garcia-Bellido, Juan

2017-01-01

A strong experimental effort is ongoing to detect the primordial gravitational waves (GW) generated during inflation from their impact on the Cosmic Microwave Background (CMB). This effort is motivated by the direct relation between the amplitude of GW signal and the energy scale of inflation, in the standard case of GW production from vacuum. I will discuss the robustness of this relation and the conditions under which particle production mechanisms during inflation can generate a stronger GW signal than the vacuum one. I will present a concrete model employing a coupling between a rolling axion and a gauge field, that can produce a detectable GW signal for an arbitrarily small inflation scale, respecting bounds from back-reaction, perturbativity, and the gaussianity of the measured density perturbations. I will show how the GW produced by this mechanism can be distinguished from the vacuum ones by their spectral dependence and statistical properties. I will finally discuss the possibility of detecting an inflationary GW signal at terrestrial (AdvLIGO) and space (LISA) interferometers. Such experiments are sensitive to the modes much smaller than the ones corresponding to CMB and Large Scale Structure, presenting a unique observational window on the final stages of inflation. The work of C.U. is s supported by a Doctoral Dissertation Fellowship from the Graduate School of the University of Minnesota.

GAPP: A Proteogenomic Software for Genome Annotation and Global Profiling of Post-translational Modifications in Prokaryotes.

PubMed

Zhang, Jia; Yang, Ming-Kun; Zeng, Honghui; Ge, Feng

2016-11-01

Although the number of sequenced prokaryotic genomes is growing rapidly, experimentally verified annotation of prokaryotic genome remains patchy and challenging. To facilitate genome annotation efforts for prokaryotes, we developed an open source software called GAPP for genome annotation and global profiling of post-translational modifications (PTMs) in prokaryotes. With a single command, it provides a standard workflow to validate and refine predicted genetic models and discover diverse PTM events. We demonstrated the utility of GAPP using proteomic data from Helicobacter pylori, one of the major human pathogens that is responsible for many gastric diseases. Our results confirmed 84.9% of the existing predicted H. pylori proteins, identified 20 novel protein coding genes, and corrected four existing gene models with regard to translation initiation sites. In particular, GAPP revealed a large repertoire of PTMs using the same proteomic data and provided a rich resource that can be used to examine the functions of reversible modifications in this human pathogen. This software is a powerful tool for genome annotation and global discovery of PTMs and is applicable to any sequenced prokaryotic organism; we expect that it will become an integral part of ongoing genome annotation efforts for prokaryotes. GAPP is freely available at https://sourceforge.net/projects/gappproteogenomic/. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

42 CFR 422.157 - Accreditation organizations.

Code of Federal Regulations, 2010 CFR

2010-10-01

..., on an annual basis, summary data specified by CMS that relate to the past year's accreditation... respect to the standard or standards in question. (2) It complies with the application and reapplication... term of the approval, which may not exceed 6 years. (c) Ongoing responsibilities of an approved...

77 FR 72691 - Small Business Size Standards: Administrative and Support, Waste Management and Remediation Services

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-06

...: Administrative and Support, Waste Management and Remediation Services AGENCY: U.S. Small Business Administration..., Administrative and Support, Waste Management and Remediation Services. As part of its ongoing comprehensive... size standard for Environmental Remediation Services, an ``exception'' under NAICS 562910, Remediation...

Quality specifications and standard-setting for stoma care patients.

PubMed

Primer, M A

1995-12-01

Quality specifications can be used as an information resource by purchasers of health care. The nature of service provision and nursing care can be positively influenced by the formalisation of standards and quality specifications. Auditing is essential in the ongoing evaluation of a quality system.

AASA Survey: Impact of the Economic Downturn on School Jobs

ERIC Educational Resources Information Center

AASA, The School Superintendent's Association, 2009

2009-01-01

As part of an ongoing effort to gauge how school districts across the country are responding to the current economic downturn, the American Association of School Administrators (AASA) continues to assess various measures of economic impact. Earlier AASA surveys addressed trends in districts' initial responses to the downturn, districts'…

A Characterization of Individual Differences in Prospective Memory Monitoring Using the Complex Ongoing Serial Task

ERIC Educational Resources Information Center

Savine, Adam C.; McDaniel, Mark A.; Shelton, Jill Talley; Scullin, Michael K.

2012-01-01

Prospective memory--remembering to retrieve and execute future goals--is essential to daily life. Prospective remembering is often achieved through effortful monitoring; however, potential individual differences in monitoring patterns have not been characterized. We propose 3 candidate models to characterize the individual differences present in…

Yavapai College Student Satisfaction Survey Conducted December 2002.

ERIC Educational Resources Information Center

Yavapai Coll., Prescott, AZ.

Yavapai College, Arizona, conducted a telephone survey of current college students in December 2002. The survey provides data for future marketing efforts, as well as providing information to be used as part of an ongoing assessment of student opinions and needs. An independent telemarketing firm called students from a random list of 1,400 credit…

Community Chairs as a Catalyst for Campus Collaborations in STEM

ERIC Educational Resources Information Center

Grandgenett, Neal; Edick, Nancy; Boocker, Dave; Ali, Hesham; Hodge, Angie; Dorn, Brian; Cutucache, Christine

2015-01-01

Strong collaborative partnerships are critical to the ongoing success of any urban or metropolitan university in its efforts to build the science, technology, engineering, and mathematics (STEM) career pathways so critical to our nation. At the University of Nebraska at Omaha, we have established a faculty leadership structure of "community…

A Study of Perceived Admission and Achievement Barriers of Learning-Disabled Students in Postsecondary Institutions

ERIC Educational Resources Information Center

Lamberg, Catherine Denise

2012-01-01

Learning-disabled students face ongoing challenges in higher education. Despite efforts to promote recruitment and retention of students with learning disabilities to trade schools, colleges, and universities, barriers to enrollment and academic achievement persist. Barriers for learning-disabled students are not fully understood and might be…

Social Determinants of Educational Outcomes in Indigenous Learners

ERIC Educational Resources Information Center

Chandler, Michael J.

2010-01-01

For the better part of two decades, the author and his research colleagues have been engaged in a broad program of research aimed at identifying certain of the "social determinants of health and wellbeing" common to Canadian First Nation, Metis, and Inuit youth. The present account samples from these ongoing research efforts by recapping…

The California Wildlife/Fish Habitat Relationship System

Treesearch

William E. Grenfell; Hal Salwasser; William F. Laudenslayer

1982-01-01

The California Wildlife/Fish Habitat Relationships (WFHR) System is an ongoing effort to apply our knowledge of wildlife habitat requirements to identify and explain the consequences of proposed land use activities, particularly those activities that affect vegetation. The U.S. Forest Service initiated the WFHR program in California in 1976 and has developed it for all...

75 FR 69086 - Submission for OMB review; comment request; NCCAM Office of Communications and Public Liaison...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-11-10

...) formative and (2) evaluative research of a variety of print and online materials, outreach activities, and... evaluative research on existing materials and messages, as part of OCPL's ongoing effort to develop a comprehensive program of testing and evaluation of all of its communications strategies. This evaluative...

75 FR 61763 - Submission for OMB Review; Comment Request; NCCAM Office of Communications and Public Liaison...

Federal Register 2010, 2011, 2012, 2013, 2014

2010-10-06

...) formative and (2) evaluative research of a variety of print and online materials, outreach activities, and... evaluative research on existing materials and messages, as part of OCPL's ongoing effort to develop a comprehensive program of testing and evaluation of all of its communications strategies. This evaluative...

Biological Effects–Based Tools for Monitoring Impacted Surface Waters in the Great Lakes: A Multiagency Program in Support of the Great Lakes Restoration Initiative

EPA Science Inventory

There is increasing demand for the implementation of effects-based monitoring and surveillance (EBMS) approaches in the Great Lakes Basin to complement traditional chemical monitoring. Herein, we describe an ongoing multiagency effort to develop and implement EBMS tools, particul...

Potential for extending major land resource areas into northern Mexico

Treesearch

Roy S. Mann; Philip Heilman; Jeffry Stone

2013-01-01

There is a significant history of cooperative efforts between Mexico and the United States on natural resource management issues. Mexico and the United States have jointly conducted research and developed range management technologies. Bringing these technologies together and improving technical communications are an ongoing process. This paper discusses a potential...

Partnerships and volunteers in the U.S. Forest Service

Treesearch

James D. Absher

2009-01-01

The U.S. Forest Service often relies on volunteers and partnerships to help accomplish agency goals, particularly in its recreation and heritage programs. Data from agency records and a staff survey suggest that volunteer involvement is a developing area. Ongoing efforts to improve the agency's volunteer management capacity (VMC) would benefit from more attention...

Overview of NASA Cryocooler Programs

NASA Technical Reports Server (NTRS)

Boyle, R. F.; Ross, R. G., Jr.; Krebs, Carolyn A. (Technical Monitor)

2001-01-01

Mechanical cryocoolers represent a significant enabling technology for NASA's Earth and Space Science Enterprises, as well as augmenting existing capabilities in space exploration. An over-view is presented of on-going efforts at the Goddard Space Flight Center and the Jet Propulsion Laboratory in support of current flight projects, near-term flight instruments, and long-term technology development.

77 FR 75243 - Self-Regulatory Organizations; Options Clearing Corporation; Order Approving Proposed Rule Change...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-12-19

... modeling and risk management procedures (``Risk Management Proposal'') \\9\\ is approved by the Commission.... The enhancements are part of OCC's ongoing efforts to test and improve its risk management operations... Index Options,\\12\\ and only subject to the filing and approval of the Risk Management Proposal, as...

78 FR 27479 - Notice of Request for Approval To Continue To Collect New Information: Confidential Close Call...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-05-10

... project. This data collection effort is in support of a five-year research study aiming at improving rail... ongoing research study is conducted by the Office of Human Factors in the Federal Railroad Administration... DEPARTMENT OF TRANSPORTATION Research and Innovative Technology Administration [Docket Number RITA...

Using Public Posting as a Motivation Strategy in Physical Education, Sport, and Adult Exercise Settings

ERIC Educational Resources Information Center

Martin, Matt; Sharpe, Tom

2009-01-01

One of the ongoing challenges that physical educators, coaches, and fitness professionals face is discovering and implementing motivational strategies that encourage long-term participation and effort. This challenge exists in public school physical education classes, on the playing field, and in structured adult physical activity settings. In…

Office of the Under Secretary of Defense (Comptroller)

Science.gov Websites

provide all of the information you need to understand the budget and financial management policy of the functionalStatements OUSD(C) History FMR Budget Materials Budget Execution Financial Management Improving Financial will also find information about the Department's ongoing effort to improve efficiency and

Observer Training Manual for the Changing Teacher Practice Study. Revised Manual.

ERIC Educational Resources Information Center

Barnes, Susan

This observer training manual was developed as a central component of a research effort, Changing Teacher Practice (CTP), which was designed to increase the frequency of effective teaching behaviors and staff development strategies in an ongoing school system. The observations focused on two major aspects of classroom teaching--instruction and…

Resource Requirements and Costs of Developing and Delivering MOOCs

ERIC Educational Resources Information Center

Hollands, Fiona M.; Tirthali, Devayani

2014-01-01

Given the ongoing alarm regarding uncontrollable costs of higher education, it would be reasonable to expect not only concern about the impact of MOOCs on educational outcomes, but also systematic efforts to document the resources expended on their development and delivery. However, there is little publicly available information on MOOC costs that…

Pilot Guidelines for Improving Instructional Materials Through the Process of Learner Verification and Revision.

ERIC Educational Resources Information Center

Educational Products Information Exchange Inst., Stony Brook, NY.

Learner Verification and Revision (LVR) Process of Instructional Materials is an ongoing effort for the improvement of instructional materials based on systematic feedback from learners who have used the materials. This evaluation gives publishers a method of identifying instructional strengths and weaknesses of a product and provides an…

78 FR 10167 - Pollinator Summit: Status of Ongoing Collaborative Efforts To Protect Pollinators; Notice of...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-02-13

... in activities to reduce potential acute exposure of honey bees and pollinators to pesticides. Invited... exposure of honey bees and pollinators to pesticides. This action is directed to the public in general, and... crops. While there are several factors affecting honey bee health, pesticides are among these variables...

Integrating species distributional, conservation planning, and individual based population models: A case study in critical habitat evaluation for the Northern Spotted Owl

EPA Science Inventory

Background / Question / Methods As part of the ongoing northern spotted owl recovery planning effort, we evaluated a series of alternative potential critical habitat scenarios using a species-distribution model (MaxEnt), a conservation-planning model (Zonation), and an individua...

Towards a Caring Community: Modeling, Dialogue, Practice, and Confirmation.

ERIC Educational Resources Information Center

Harris, Charlotte Matthews

A teacher educator, engaged in ongoing practitioner inquiry to explore self as well as program, examines her evolution as a teacher of teachers through reflection, systematic inquiry, and collaboration. Relating autobiographically, she conjures up her professional stories and listens to her voice in an effort to define and refine her role, reflect…

Analysis of Shadowing Effects on Spacecraft Power Systems

NASA Technical Reports Server (NTRS)

1995-01-01

As part of an ongoing effort within the NASA Lewis Research Center's Power Systems Project Office to assist in the design and characterization of future space-based power systems, analyses have been performed to assess the effects of shadowing on the capabilities of various power systems on the International Space Station and the Russian MIR.

Forum on Emerging Infectious Diseases Highlights Leading-Edge Research | Poster

Cancer.gov

Scientists and professionals from multiple governmental agencies recently gathered at NCI at Frederick for a forum on newly emerging infectious diseases, threats to public health, and ongoing efforts to study high-risk pathogens. During the one-day event, which was sponsored by the National Interagency Confederation for Biological Research’s Scientific Interaction

Solid Inflammability Boundary At Low-Speed (SIBAL)

NASA Technical Reports Server (NTRS)

T'ien, J.; Sacksteder, K.; Ferkul, P.; Pettegrew, R.; Street, K.; Kumar, A.; Tolejko, K.; Kleinhenz, J.; Piltch, N.

2003-01-01

This research program is concerned with the effect of low-speed flow on the spreading and extinction processes over solid fuels. The project has passed the Science Concept Review and the experiment is currently scheduled to be performed in the ISS Combustion Integrated Rack. We present an overview of recent and ongoing experimental and theoretical efforts.

High School/College Partnerships. 1981 Current Issues in Higher Education, No 1.

ERIC Educational Resources Information Center

American Association for Higher Education, Washington, DC.

The need for better high school/college articulation is addressed in five papers. In "High School/College Partnerships That Work," Ernest L. Boyer describes the ongoing efforts to encourage high school/college collaboration and considers five principles necessary for establishing cooperative programs, including the need for educators at…

A Progress Report on an Exploratory Mathematics Course: Incorporating a Programming Component

ERIC Educational Resources Information Center

Goldberg, Robert; Waxman, Jerry

2004-01-01

This paper reports on an ongoing effort to incorporate a programming component into exploratory mathematics courses and analyzes some of the many practical considerations required for successfully managing such a course in large lecture hall classes. Two pedagogical paradigms (top-down and bottom-up) are compared and contrasted for teaching Visual…

The NMC Horizon Report: 2011 K-12 Edition

ERIC Educational Resources Information Center

Johnson, L.; Adams, S.; Haywood, K.

2011-01-01

"The NMC Horizon Report" series is the most visible outcome of the New Media Consortium. (NMC) Horizon Project, an ongoing research effort established in 2002 that identifies and describes emerging technologies likely to have a large impact on teaching, learning, research, or creative expression within education around the globe. This volume, "The…

Conceptions of Evidence Use in School Districts: Mapping the Terrain

ERIC Educational Resources Information Center

Coburn, Cynthia E.; Talbert, Joan E.

2006-01-01

Current policies place unprecedented demands on districts to use evidence to guide their educational improvement efforts. How districts respond is likely to be influenced by how individuals in the district conceptualize what it means to use evidence in their ongoing work. This study draws on sensemaking and institutional theory to investigate how…

Facing Fears: The Feasibility of Anxiety Universal Prevention Efforts with Children and Adolescents

ERIC Educational Resources Information Center

Miller, Lynn D.

2008-01-01

A few comprehensive reviews of the effectiveness of prevention programs of mental disorders in school-age children ((Greenberg et al., 2003) and (Weisz et al., 2005)) conclude that while several well-designed studies demonstrate the potential of preventive intervention, greater attention and ongoing rigorous research is critical. The benefits and…

Building Lectures and Building Bridges with Socio-Economically Disadvantaged Students

ERIC Educational Resources Information Center

Phillips, Peter; Loch, Birgit

2011-01-01

This paper is an empirical analysis of the first stage of an ongoing effort to introduce technology to enhance student learning in introductory corporate finance within a multi-campus and multi-mode regional Australian University. The engagement and performance of low socio-economic status (SES) students is of particular interest because…

Opening Teachers' Minds to Philosophy: The Crucial Role of Teacher Education

ERIC Educational Resources Information Center

Knight, Sue; Collins, Carol

2014-01-01

Why has the "Philosophy for Children" movement failed to make significant educational inroads in Australia, given the commitment and ongoing efforts of philosophers and educators alike who have worked hard in recent decades to bring philosophy to our schools? In this article we single out one factor as having particular importance,…

77 FR 3781 - Pediatric Medical Devices; Public Workshop; Reopening of Comment Period

Federal Register 2010, 2011, 2012, 2013, 2014

2012-01-25

... discussion of how to determine when it is appropriate to use, and how to use, existing scientific research... use of scientific research data to support pediatric medical device efficacy claims. This is part of an on-going effort to address the ways scientific research data can be used to support pediatric...

Creative Tension: Turn The Challenges of Learning Together Into Opportunities

ERIC Educational Resources Information Center

Dobbs, Christina L.; Ippolito, Jacy; Charner-Laird, Megin

2016-01-01

Effective and authentic communities of practice in schools have the potential to support teachers in improving their instructional practices around perennial challenges, such as improving the literacy skills of all students. But before they can achieve such goals, communities of practice take time to build, effort to sustain, and ongoing support…

Information as Power. An Anthology of Selected United States Army War College Student Papers. Volume 4

DTIC Science & Technology

2010-01-01

Coombs , Crisis Management and Communication ...and coordinating all U.S. PSYOP efforts in Afghanistan. 14. Coombs , Crisis Management and Communication . 15. Coombs , Ongoing Crisis ...commonly associated with, and seen as a requirement in, crisis response communications . A crisis is “a significant threat to operations

Toward The Identification Of Candidate Genes Involved In Black Pod Disease Resistance In Theobroma cacao L.

USDA-ARS?s Scientific Manuscript database

Black Pod (Phytophthora sp.) has a devastating effect on the worldwide cacao (Theobroma cacao) yield and incorporating resistance into production fields has been an ongoing effort of breeding programs. Previous meta-QTL analysis of genetic maps created with a variety of molecular markers identified...

Toward the identification of candidate genes involved In black pod disease resistance in Theobroma cacao L.

USDA-ARS?s Scientific Manuscript database

Black Pod (Phytophthora sp.) has a devastating effect on the worldwide cacao (Theobroma cacao) yield and incorporating resistance into production fields has been an ongoing effort of breeding programs. Previous meta-QTL analysis of genetic maps created with a variety of molecular markers identified...

WORKSHOP ON MERCURY IN PRODUCTS, PROCESSES, WASTE AND THE ENVIRONMENT: ELIMINATING, REDUCING AND MANAGING RISKS FROM NON-COMBUSTION SOURCES (PROGRAM FLYER)

EPA Science Inventory

The Workshop is designed to achieve three goals:
1. Convey public and private sector perspectives on the management of mercury in products, processes, and wastes;
2. Present ongoing efforts that address mercury prevention, elimination, noncombustion treatment and disposal; ...

76 FR 57050 - Approaches to Reducing Sodium Consumption; Establishment of Dockets; Request for Comments, Data...

Federal Register 2010, 2011, 2012, 2013, 2014

2011-09-15

... stroke. FDA and FSIS recognize ongoing efforts by a number of members of the restaurant and packaged food... manufacturing of foods and preparation of restaurant foods, reduction in sodium consumption in the United States... Act of 2010, certain restaurants and similar retail food establishments must provide, upon request...

Academic Program Review--Concerns and Justification.

ERIC Educational Resources Information Center

Heldman, D. R.

Academic program review should not be considered a new phenomenon in higher education; reviews of various types have been conducted on a continuing basis. The renewed importance of an organized effort has been stimulated by the inability of funding sources to maintain levels of support required to insure quality in all on-going programs. Current…

Balancing Good Intentions: Protecting the Privacy of Electronic Health Information

ERIC Educational Resources Information Center

McClanahan, Kitty

2008-01-01

Electronic information is a vital but complex component in the modern health care system, fueling ongoing efforts to develop a universal electronic health record infrastructure. This innovation creates a substantial tension between two desirable values: the increased quality and utility of patient medical records and the protection of the privacy…

Probing High School Physics Students' Views and Concerns about Learning Activities

ERIC Educational Resources Information Center

Langley, Dorothy; Eylon, Bat-Sheva

2006-01-01

The current study is framed within an ongoing effort of probing students' attitudes and expectations about knowing and learning physics, which has driven several investigations during the past decade. The questionnaire we developed focuses on physics students' views regarding a variety of specific learning activities, which are presented by title…

Stirling engines for automobiles

NASA Technical Reports Server (NTRS)

Beremand, D. G.

1979-01-01

The results of recent and ongoing automobile Stirling engine development efforts are reviewed and technology status and requirements are identified. Key technology needs include those for low cost, high temperature (1300 - 1500 F) metal alloys for heater heads, and reliable long-life, low-leakage shaft seals. Various fuel economy projections for Stirling powered automobiles are reviewed and assessed.

78 FR 46362 - Information Collection Sent to the Office of Management and Budget (OMB) for Approval; National...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-31

..., nongovernmental organizations; and academic institutions to advance the development of The National Map and other national geospatial databases. This effort will support our need to supplement ongoing data collection.... Description of Respondents: State, local, and tribal governments; private and non-profit firms; and academic...

The Program Evaluator's Role in Cross-Project Pollination.

ERIC Educational Resources Information Center

Yasgur, Bruce J.

An expanded duties role of the multiple-program evaluator as an integral part of the ongoing decision-making process in all projects served is defended. Assumptions discussed included that need for projects with related objectives to pool resources and avoid duplication of effort and the evaluator's unique ability to provide an objective…

Field Turbidity Methods for the Determination of Lead in Acid Extracts of Dried Paint

EPA Science Inventory

Lead, which can be found in old paint, soil, and dust, has been clearly shown to have adverse health effects on the neurological systems of both children and adults. As part of an ongoing effort to reduce childhood lead poisoning, the U.S. Environmental Protection Agency promulga...

Epidemiology of Phytophthora ramorum in Oregon

Treesearch

E.M. Hansen; A. Kanaskie; E.M. Goheen; N. Osterbauer; W. Sutton

2006-01-01

We are studying how P. ramorum survives and spreads in Oregon tanoak forests. The Oregon outbreak is similar to the epidemic in redwood-tanoak forests of California, with several important differences, however. The disease is confined to scattered stands within a 12 m2 area, and it is subject to an ongoing eradication effort....

Language Revitalization Processes and Prospects: Quichua in the Ecuadorian Andes.

ERIC Educational Resources Information Center

King, Kendall A.

This paper examines efforts to reverse language shift in two indigenous communities in southern Ecuador. The ongoing decline and rapid pace of extinction of many of the world's languages have received increasing amounts of attention, but while processes of language loss and extinction have been extensively studied, relatively little work of…

The NMC Horizon Report: 2014 K-12 Edition

ERIC Educational Resources Information Center

Johnson, L.; Adams Becker, S.; Estrada, V.; Freeman, A.

2014-01-01

"The NMC Horizon Report" series is the most visible outcome of the New Media Consortium (NMC) Horizon Project, an ongoing research effort established in 2002 that identifies and describes emerging technologies likely to have a large impact on teaching, learning, research, or creative expression within every sector of education in some 65…

Virtual Environments and the Ongoing Work of Becoming a Singapore Teacher

ERIC Educational Resources Information Center

Zuiker, Steven J.; Ang, Doreen

2011-01-01

The study explores the intersection between cyberinfrastructure and models of teacher education and professional development in Singapore. A case study explores how a pre-service and an in-service workshop in a virtual environment support efforts to understand and enlist constructivist pedagogies for classroom learning and to foster continuous…

77 FR 5661 - Equal Access to Housing in HUD Programs Regardless of Sexual Orientation or Gender Identity

Federal Register 2010, 2011, 2012, 2013, 2014

2012-02-03

... from targeted violence. Passage of the law resulted from the ongoing efforts of individuals personally impacted by hate crime violence, together with nearly 300 civil rights and religious organizations... the proposal continues to promote negative stereotypes and violence against LGBT persons. A commenter...

ASAS-SN Discovery of a Bright Be Star Undergoing a Possible Outburst

NASA Astrophysics Data System (ADS)

Jayasinghe, T.; Stanek, K. Z.; Kochanek, C. S.; Thorstensen, J.; Rupert, J.; Prieto, J. L.; Shields, J. V.; Thompson, T. A.; Holoien, T. W.-S.; Shappee, B. J.; Dong, Subo

2017-09-01

As part of an ongoing effort by ASAS-SN project (Shappee et al. 2014; Kochanek et al. 2017) to characterize and catalog all bright variable stars (e.g., Jayasinghe et al. 2017, ATel #10634, #10677), we report the discovery of a bright Be star undergoing a possible outburst.

Effectiveness of conservation reserve program buffers in the Chesapeake Bay Watershed: 2017 annual report

USDA-ARS?s Scientific Manuscript database

Riparian buffers play an important role in watershed strategies to clean up the Chesapeake Bay, with over 20,000 riparian buffers implemented in the Chesapeake Bay watershed under USDA’S Conservation Reserve Enhancement Program (CREP). This annual report documents an on-going, multi-agency effort to...

Building Scientific Confidence in the Development and Evaluation of Read-Across Using Tox21 Approaches (SOT Annual Meeting)

EPA Science Inventory

Acceptance of read-across is an ongoing challenge and several efforts are underway to identify and address major uncertainties associated with read-across. Several approaches have been proposed but to date few case studies if any have evaluated how Tox21 approaches may be instruc...

78 FR 6321 - PacifiCorp, et al; Notice of FERC Staff Attendance

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-30

...Corp, et al; Notice of FERC Staff Attendance PacifiCorp Docket No. ER13-64-000 Deseret Generation... Regulatory Commission (Commission) hereby gives notice that on January 30, 2013, members of its staff will... and Commission staff's attendance is part of the Commission's ongoing outreach efforts. The meeting...

Going to University: Pacific Island Migrant Perspectives

ERIC Educational Resources Information Center

Cuthill, Michael; Scull, Sue

2011-01-01

Despite extensive and on-going efforts, people from a low socio-economic background continue to be significantly under-represented in Australian higher education. In response to this situation, a two year action research project explored the broad issue of higher education access for young people from low socio-economic backgrounds in South East…

Assessing Greenhouse Gas Emissions from University Purchases

ERIC Educational Resources Information Center

Thurston, Matthew; Eckelman, Matthew J.

2011-01-01

Purpose: A greenhouse gas (GHG) inventory was conducted for Yale University's procurement of goods and services over a one-year period. The goal of the inventory was to identify the financial expenditures resulting in the greatest "indirect" GHG emissions. This project is part of an ongoing effort to quantify and reduce the university's…

The "Synergies" Research-Practice Partnership Project: A "2020 Vision" Case Study

ERIC Educational Resources Information Center

Falk, John H.; Dierking, Lynn D.; Staus, Nancy L.; Wyld, Jennifer N.; Bailey, Deborah L.; Penuel, William R.

2016-01-01

This paper, describes "Synergies," an on-going longitudinal study and design effort, being conducted in a diverse, under-resourced community in Portland, Oregon, with the goal of measurably improving STEM learning, interest and participation by early adolescents, both in school and out of school. Authors examine how the work of this…

Implementing Restorative Justice Practice in Schools: What Pedagogy Reveals

ERIC Educational Resources Information Center

Vaandering, Dorothy

2014-01-01

In the ongoing pursuit for creating safe, nurturing and relational school cultures, educators continue to turn to restorative justice (rj) principles and practice. Predominantly, schools begin to engage with rj in an effort to address harm done, causing its discourse to be situated in literature tied to classroom management and behaviour. However,…

Literacy Teacher Preparation: Ten Truths Teacher Educators Need to Know

ERIC Educational Resources Information Center

Davis Lenski, Susan, Ed.; Grisham, Dana L., Ed.; Wold, Linda S., Ed.

2005-01-01

The quality of teacher preparation is frequently under public scrutiny. In this collection, experts in literacy teacher preparation offer ten truths--based on evidence, not ideology-- that support the ongoing positive efforts of teacher educators. In this book, the reader will find: A review of the existing knowledge base; Evidence of the improved…

A Combined Research/Educational Curriculum in Smart Sensors and Integrated Devices.

ERIC Educational Resources Information Center

Auner, G. W.; Siy, P.; Naik, R.; Wenger, L.; Liu, G-Y.; Schwiebert, L. J.

The researchers are developing a new curriculum which integrates ongoing research efforts in the Center for Smart Sensors and Integrated Devices into a cooperative educational and traineeship program. A forerunner to this program was initiated with funding by a National Science Foundation (NSF) Combined Research and Curriculum Development (CRCD)…

Legal liability for Agent Orange-related illnesses: a reassessment of the 2005 VAVA case and prospects for new litigation.

PubMed

Klickermann, Felix

2016-01-01

Attempts through the US courts to hold the corporations responsible for the production of dioxin-contaminated herbicides used by the US military in the 1960s and early 1970s liable for their ongoing health consequences have failed. This article scrutinizes the most recent judgement - that of the United States District Court for the Eastern District of New York handed down in 2005 following a lawsuit brought by the Vietnam Association of Victims of Agent Orange/dioxin (VAVA). It is argued that despite this judgement there is the potential to bring a further legal case, with some prospect of success, on the basis of: (i) debatable legal judgements in the 2005 decision; (ii) new scientific evidence on the health effects of exposure to Agent Orange; and (iii) cases brought in other jurisdictions. The article concludes by noting the underfunding of ongoing remediation efforts, especially for the provision of assistance to affected individuals, and argues that it is desirable to oblige the producers of the herbicides to contribute financially to these efforts.

Cataloging Practices in India: Efforts for Standardization.

ERIC Educational Resources Information Center

Tikku, Upinder Kumar

1984-01-01

Surveys current cataloging practices in Indian libraries and discusses standardization in cataloging, types of catalogs, cataloging codes (Anglo-American and Ranganathan), subject headings, descriptive cataloging, and standardization efforts (international, United States, USSR, Great Britain, India). Footnotes are included. (EJS)

Advanced Curation Activities at NASA: Preparing to Receive, Process, and Distribute Samples Returned from Future Missions

NASA Technical Reports Server (NTRS)

McCubbin, Francis M.; Zeigler, Ryan A.

2017-01-01

The Astromaterials Acquisition and Curation Office (henceforth referred to herein as NASA Curation Office) at NASA Johnson Space Center (JSC) is responsible for curating all of NASA's extraterrestrial samples. Under the governing document, NASA Policy Directive (NPD) 7100.10F JSC is charged with curation of all extraterrestrial material under NASA control, including future NASA missions. The Directive goes on to define Curation as including documentation, preservation, preparation, and distribution of samples for research, education, and public outreach. Here we briefly describe NASA's astromaterials collections and our ongoing efforts related to enhancing the utility of our current collections as well as our efforts to prepare for future sample return missions. We collectively refer to these efforts as advanced curation.

Inhibition of Ras for cancer treatment: the search continues

PubMed Central

Baines, Antonio T.; Xu, Dapeng; Der, Channing J.

2012-01-01

Background The RAS oncogenes (HRAS, NRAS and KRAS) comprise the most frequently mutated class of oncogenes in human cancers (33%), stimulating intensive effort in developing anti-Ras inhibitors for cancer treatment. Discussion Despite intensive effort, to date no effective anti-Ras strategies have successfully made it to the clinic. We present an overview of past and ongoing strategies to inhibit oncogenic Ras in cancer. Conclusions Since approaches to directly target mutant Ras have not been successful, most efforts have focused on indirect approaches to block Ras membrane association or downstream effector signaling. While inhibitors of effector signaling are currently under clinical evaluation, genome-wide unbiased genetic screens have identified novel directions for future anti-Ras drug discovery. PMID:22004085

Advanced Curation Activities at NASA: Implications for Astrobiological Studies of Future Sample Collections

NASA Technical Reports Server (NTRS)

McCubbin, F. M.; Evans, C. A.; Fries, M. D.; Harrington, A. D.; Regberg, A. B.; Snead, C. J.; Zeigler, R. A.

2017-01-01

The Astromaterials Acquisition and Curation Office (henceforth referred to herein as NASA Curation Office) at NASA Johnson Space Center (JSC) is responsible for curating all of NASA's extraterrestrial samples. Under the governing document, NASA Policy Directive (NPD) 7100.10F JSC is charged with curation of all extraterrestrial material under NASA control, including future NASA missions. The Directive goes on to define Curation as including documentation, preservation, preparation, and distribution of samples for re-search, education, and public outreach. Here we briefly describe NASA's astromaterials collections and our ongoing efforts related to enhancing the utility of our current collections as well as our efforts to prepare for future sample return missions. We collectively refer to these efforts as advanced curation.

Protein crystallization studies

NASA Technical Reports Server (NTRS)

Lyne, James Evans

1996-01-01

The Structural Biology laboratory at NASA Marshall Spaceflight Center uses x-ray crystallographic techniques to conduct research into the three-dimensional structure of a wide variety of proteins. A major effort in the laboratory involves an ongoing study of human serum albumin (the principal protein in human plasma) and its interaction with various endogenous substances and pharmaceutical agents. Another focus is on antigenic and functional proteins from several pathogenic organisms including the human immunodeficiency virus (HIV) and the widespread parasitic genus, Schistosoma. My efforts this summer have been twofold: first, to identify clinically significant drug interactions involving albumin binding displacement and to initiate studies of the three-dimensional structure of albumin complexed with these agents, and secondly, to establish collaborative efforts to extend the lab's work on human pathogens.

Information campaign and advocacy efforts to promote access to emergency contraception in Mexico.

PubMed

Ellertson, Charlotte; Heimburger, Angela; Acevedo-Garcia, Dolores; Schiavon, Raffaela; Mejia, Guillermina; Corona, Georgina; del Castillo, Eduardo; Langer, Ana

2002-11-01

Emergency contraception (EC) has the potential to reduce unwanted pregnancy significantly, in Mexico as elsewhere. Recent years have seen tremendous growth in programs and research devoted to expanding access to emergency methods worldwide. In Mexico we developed a comprehensive model introduction effort that included four components: provider training, public information (through a dedicated hotline and website, free media, paid radio and TV spots, participation in talk shows, and alternative media channels), collaboration with the public sector to include EC in the official family planning norms, and assistance to partner with commercial firms to register a dedicated EC product. Ongoing efforts to combat misperceptions and overcome opposition are crucial to informing the public and ensuring greater access to the method.

78 FR 42975 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-American Massage...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-07-18

... standards in cooperation with the Alliance for Massage Therapy Education, Associated Bodywork and Massage..., the Massage Therapy Foundation, and the National Certification Board for Therapeutic Massage and... training and education in massage therapy. AMTA's standards development activities are ongoing in nature...

78 FR 14836 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-ASTM...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-03-07

... Production Act of 1993--ASTM International Standards Notice is hereby given that, on February 11, 2013... seq. (``the Act''), ASTM International (``ASTM'') has filed written notifications simultaneously with..., ASTM has provided an updated list of current, ongoing ASTM standards activities originating between...

77 FR 34069 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-ASTM...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-06-08

... Production Act of 1993--ASTM International Standards Notice is hereby given that, on May 11, 2012, pursuant... seq. (``the Act''), ASTM International (``ASTM'') has filed written notifications simultaneously with..., ASTM has provided an updated list of current, ongoing ASTM standards activities originating between...

78 FR 64248 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-ASTM...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-10-28

... Production Act of 1993--ASTM International Standards Notice is hereby given that, on September 16, 2013... seq. (``the Act''), ASTM International (``ASTM'') has filed written notifications simultaneously with..., ASTM has provided an updated list of current, ongoing ASTM standards activities originating between May...

78 FR 35646 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-ASTM...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-06-13

... Production Act of 1993--ASTM International Standards Notice is hereby given that, on May 10, 2013, pursuant... seq. (``the Act''), ASTM International (``ASTM'') has filed written notifications simultaneously with..., ASTM has provided an updated list of current, ongoing ASTM standards activities originating between...

77 FR 61786 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-ASTM...

Federal Register 2010, 2011, 2012, 2013, 2014

2012-10-11

... Production Act of 1993--ASTM International Standards Notice is hereby given that, on September 10, 2012... seq. (``the Act''), ASTM International (``ASTM'') has filed written notifications simultaneously with..., ASTM has provided an updated list of current, ongoing ASTM standards activities originating between May...

78 FR 1884 - Notice Pursuant to the National Cooperative Research and Production Act of 1993-ASTM...

Federal Register 2010, 2011, 2012, 2013, 2014

2013-01-09

... Production Act of 1993--ASTM International Standards Notice is hereby given that, on December 12, 2012... seq. (``the Act''), ASTM International (``ASTM'') has filed written notifications simultaneously with..., ASTM has provided an updated list of current, ongoing ASTM standards activities originating between...

EDI-The Future.

ERIC Educational Resources Information Center

Rusk, Harriet J.

1991-01-01

Considered are standardization efforts of the American National Standards Institute's Accredited Standards Committee X12 concerned with electronic data interchange (EDI). These efforts will effect dentistry first in the transmission of academic records, and then in communications between dental offices and businesses, including major insurance…

Steps toward a CONUS-wide reanalysis with archived NEXRAD data using National Mosaic and Multisensor Quantitative Precipitation Estimation (NMQ/Q2) algorithms

NASA Astrophysics Data System (ADS)

Stevens, S. E.; Nelson, B. R.; Langston, C.; Qi, Y.

2012-12-01

The National Mosaic and Multisensor QPE (NMQ/Q2) software suite, developed at NOAA's National Severe Storms Laboratory (NSSL) in Norman, OK, addresses a large deficiency in the resolution of currently archived precipitation datasets. Current standards, both radar- and satellite-based, provide for nationwide precipitation data with a spatial resolution of up to 4-5 km, with a temporal resolution as fine as one hour. Efforts are ongoing to process archived NEXRAD data for the period of record (1996 - present), producing a continuous dataset providing precipitation data at a spatial resolution of 1 km, on a timescale of only five minutes. In addition, radar-derived precipitation data are adjusted hourly using a wide variety of automated gauge networks spanning the United States. Applications for such a product range widely, from emergency management and flash flood guidance, to hydrological studies and drought monitoring. Results are presented from a subset of the NEXRAD dataset, providing basic statistics on the distribution of rainrates, relative frequency of precipitation types, and several other variables which demonstrate the variety of output provided by the software. Precipitation data from select case studies are also presented to highlight the increased resolution provided by this reanalysis and the possibilities that arise from the availability of data on such fine scales. A previously completed pilot project and steps toward a nationwide implementation are presented along with proposed strategies for managing and processing such a large dataset. Reprocessing efforts span several institutions in both North Carolina and Oklahoma, and data/software coordination are key in producing a homogeneous record of precipitation to be archived alongside NOAA's other Climate Data Records. Methods are presented for utilizing supercomputing capability in expediting processing, to allow for the iterative nature of a reanalysis effort.

Avionics Architectures for Exploration: Ongoing Efforts in Human Spaceflight

NASA Technical Reports Server (NTRS)

Goforth, Montgomery B.; Ratliff, James E.; Hames, Kevin L.; Vitalpur, Sharada V.; Woodman, Keith L.

2014-01-01

The field of Avionics is advancing far more rapidly in terrestrial applications than in spaceflight applications. Spaceflight Avionics are not keeping pace with expectations set by terrestrial experience, nor are they keeping pace with the need for increasingly complex automation and crew interfaces as we move beyond Low Earth Orbit. NASA must take advantage of the strides being made by both space-related and terrestrial industries to drive our development and sustaining costs down. This paper describes ongoing efforts by the Avionics Architectures for Exploration (AAE) project chartered by NASA's Advanced Exploration Systems (AES) Program to evaluate new avionic architectures and technologies, provide objective comparisons of them, and mature selected technologies for flight and for use by other AES projects. The AAE project team includes members from most NASA centers, and from industry. It is our intent to develop a common core avionic system that has standard capabilities and interfaces, and contains the basic elements and functionality needed for any spacecraft. This common core will be scalable and tailored to specific missions. It will incorporate hardware and software from multiple vendors, and be upgradeable in order to infuse incremental capabilities and new technologies. It will maximize the use of reconfigurable open source software (e.g., Goddard Space Flight Center's (GSFC's) Core Flight Software (CFS)). Our long-term focus is on improving functionality, reliability, and autonomy, while reducing size, weight, and power. Where possible, we will leverage terrestrial commercial capabilities to drive down development and sustaining costs. We will select promising technologies for evaluation, compare them in an objective manner, and mature them to be available for future programs. The remainder of this paper describes our approach, technical areas of emphasis, integrated test experience and results as of mid-2014, and future plans. As a part of the AES Program, we are encouraged to set aggressive goals and fall short if necessary, rather than to set our sights too low. We are also asked to emphasize providing our personnel with hands-on experience in development, integration, and testing. That we have embraced both of these philosophies will be evident in the descriptions below.