Sample records for open application test

  1. Open Education Students' Perspectives on Using Virtual Museums Application in Teaching History Subjects

    ERIC Educational Resources Information Center

    Ulusoy, Kadir

    2010-01-01

    The study was made to determine whether the attitudes of the open education faculty students, will be changed or not by virtual museum application. The pre-test and post-test model of the experimental design was used in the research. A group of 20 was formed as an experimental group. The pre-test was given to the group before the study and the…

  2. Shadow: Running Tor in a Box for Accurate and Efficient Experimentation

    DTIC Science & Technology

    2011-09-23

    Modeling the speed of a target CPU is done by running an OpenSSL [31] speed test on a real CPU of that type. This provides us with the raw CPU processing...rate, but we are also interested in the processing speed of an application. By running application 5 benchmarks on the same CPU as the OpenSSL speed test...simulation, saving CPU cy- cles on our simulation host machine. Shadow removes cryptographic processing by preloading the main OpenSSL [31] functions used

  3. An open-source framework for testing tracking devices using Lego Mindstorms

    NASA Astrophysics Data System (ADS)

    Jomier, Julien; Ibanez, Luis; Enquobahrie, Andinet; Pace, Danielle; Cleary, Kevin

    2009-02-01

    In this paper, we present an open-source framework for testing tracking devices in surgical navigation applications. At the core of image-guided intervention systems is the tracking interface that handles communication with the tracking device and gathers tracking information. Given that the correctness of tracking information is critical for protecting patient safety and for ensuring the successful execution of an intervention, the tracking software component needs to be thoroughly tested on a regular basis. Furthermore, with widespread use of extreme programming methodology that emphasizes continuous and incremental testing of application components, testing design becomes critical. While it is easy to automate most of the testing process, it is often more difficult to test components that require manual intervention such as tracking device. Our framework consists of a robotic arm built from a set of Lego Mindstorms and an open-source toolkit written in C++ to control the robot movements and assess the accuracy of the tracking devices. The application program interface (API) is cross-platform and runs on Windows, Linux and MacOS. We applied this framework for the continuous testing of the Image-Guided Surgery Toolkit (IGSTK), an open-source toolkit for image-guided surgery and shown that regression testing on tracking devices can be performed at low cost and improve significantly the quality of the software.

  4. Hydroxyisohexyl 3-cyclohexene carboxaldehyde allergy: relationship between patch test and repeated open application test thresholds.

    PubMed

    Fischer, L A; Menné, T; Avnstorp, C; Kasting, G B; Johansen, J D

    2009-09-01

    Hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC) is a synthetic fragrance ingredient. Case reports of allergy to HICC appeared in the 1980s, and HICC has recently been included in the European baseline series. Human elicitation dose-response studies performed with different allergens have shown a significant relationship between the patch-test threshold and the repeated open application test (ROAT) threshold, which mimics some real-life exposure situations. Fragrance ingredients are special as significant amounts of allergen may evaporate from the skin. The study aimed to investigate the relationship between elicitation threshold doses at the patch test and the ROAT, using HICC as the allergen. The expected evaporation rate was calculated. Seventeen HICC-allergic persons were tested with a dilution series of HICC in a patch test and a ROAT (duration up to 21 days). Seventeen persons with no HICC allergy were included as control group for the ROAT. Results The response frequency to the ROAT (in microg HICC cm(-2) per application) was significantly higher than the response frequency to the patch test at one of the tested doses. Furthermore the response rate to the accumulated ROAT dose was significantly lower at half of the doses compared with the patch test. The evaporation rate of HICC was calculated to be 72% over a 24-h period. The ROAT threshold in dose per area per application is lower than the patch test threshold; furthermore the accumulated ROAT threshold is higher than the patch test threshold, which can probably be explained by the evaporation of HICC from the skin in the open test.

  5. Free and open-source software application for the evaluation of coronary computed tomography angiography images.

    PubMed

    Hadlich, Marcelo Souza; Oliveira, Gláucia Maria Moraes; Feijóo, Raúl A; Azevedo, Clerio F; Tura, Bernardo Rangel; Ziemer, Paulo Gustavo Portela; Blanco, Pablo Javier; Pina, Gustavo; Meira, Márcio; Souza e Silva, Nelson Albuquerque de

    2012-10-01

    The standardization of images used in Medicine in 1993 was performed using the DICOM (Digital Imaging and Communications in Medicine) standard. Several tests use this standard and it is increasingly necessary to design software applications capable of handling this type of image; however, these software applications are not usually free and open-source, and this fact hinders their adjustment to most diverse interests. To develop and validate a free and open-source software application capable of handling DICOM coronary computed tomography angiography images. We developed and tested the ImageLab software in the evaluation of 100 tests randomly selected from a database. We carried out 600 tests divided between two observers using ImageLab and another software sold with Philips Brilliance computed tomography appliances in the evaluation of coronary lesions and plaques around the left main coronary artery (LMCA) and the anterior descending artery (ADA). To evaluate intraobserver, interobserver and intersoftware agreements, we used simple and kappa statistics agreements. The agreements observed between software applications were generally classified as substantial or almost perfect in most comparisons. The ImageLab software agreed with the Philips software in the evaluation of coronary computed tomography angiography tests, especially in patients without lesions, with lesions < 50% in the LMCA and < 70% in the ADA. The agreement for lesions > 70% in the ADA was lower, but this is also observed when the anatomical reference standard is used.

  6. Opening Loads Analyses for Various Disk-Gap-Band Parachutes

    NASA Technical Reports Server (NTRS)

    Cruz, J. R.; Kandis, M.; Witkowski, A.

    2003-01-01

    Detailed opening loads data is presented for 18 tests of Disk-Gap-Band (DGB) parachutes of varying geometry with nominal diameters ranging from 43.2 to 50.1 ft. All of the test parachutes were deployed from a mortar. Six of these tests were conducted via drop testing with drop test vehicles weighing approximately 3,000 or 8,000 lb. Twelve tests were conducted in the National Full-Scale Aerodynamics Complex 80- by 120-foot wind tunnel at the NASA Ames Research Center. The purpose of these tests was to structurally qualify the parachute for the Mars Exploration Rover mission. A key requirement of all tests was that peak parachute load had to be reached at full inflation to more closely simulate the load profile encountered during operation at Mars. Peak loads measured during the tests were in the range from 12,889 to 30,027 lb. Of the two test methods, the wind tunnel tests yielded more accurate and repeatable data. Application of an apparent mass model to the opening loads data yielded insights into the nature of these loads. Although the apparent mass model could reconstruct specific tests with reasonable accuracy, the use of this model for predictive analyses was not accurate enough to set test conditions for either the drop or wind tunnel tests. A simpler empirical model was found to be suitable for predicting opening loads for the wind tunnel tests to a satisfactory level of accuracy. However, this simple empirical model is not applicable to the drop tests.

  7. Software for Real-Time Analysis of Subsonic Test Shot Accuracy

    DTIC Science & Technology

    2014-03-01

    used the C++ programming language, the Open Source Computer Vision ( OpenCV ®) software library, and Microsoft Windows® Application Programming...video for comparison through OpenCV image analysis tools. Based on the comparison, the software then computed the coordinates of each shot relative to...DWB researchers wanted to use the Open Source Computer Vision ( OpenCV ) software library for capturing and analyzing frames of video. OpenCV contains

  8. OSI Conformance Testing for Bibliographic Applications.

    ERIC Educational Resources Information Center

    Arbez, Gilbert; Swain, Leigh

    1990-01-01

    Describes the development of Open Systems Interconnection (OSI) conformance testing sites, conformance testing tools, and conformance testing services. Discusses related topics such as interoperability testing, arbitration testing, and international harmonization of conformance testing. A glossary is included. (24 references) (SD)

  9. Cloud computing geospatial application for water resources based on free and open source software and open standards - a prototype

    NASA Astrophysics Data System (ADS)

    Delipetrev, Blagoj

    2016-04-01

    Presently, most of the existing software is desktop-based, designed to work on a single computer, which represents a major limitation in many ways, starting from limited computer processing, storage power, accessibility, availability, etc. The only feasible solution lies in the web and cloud. This abstract presents research and development of a cloud computing geospatial application for water resources based on free and open source software and open standards using hybrid deployment model of public - private cloud, running on two separate virtual machines (VMs). The first one (VM1) is running on Amazon web services (AWS) and the second one (VM2) is running on a Xen cloud platform. The presented cloud application is developed using free and open source software, open standards and prototype code. The cloud application presents a framework how to develop specialized cloud geospatial application that needs only a web browser to be used. This cloud application is the ultimate collaboration geospatial platform because multiple users across the globe with internet connection and browser can jointly model geospatial objects, enter attribute data and information, execute algorithms, and visualize results. The presented cloud application is: available all the time, accessible from everywhere, it is scalable, works in a distributed computer environment, it creates a real-time multiuser collaboration platform, the programing languages code and components are interoperable, and it is flexible in including additional components. The cloud geospatial application is implemented as a specialized water resources application with three web services for 1) data infrastructure (DI), 2) support for water resources modelling (WRM), 3) user management. The web services are running on two VMs that are communicating over the internet providing services to users. The application was tested on the Zletovica river basin case study with concurrent multiple users. The application is a state-of-the-art cloud geospatial collaboration platform. The presented solution is a prototype and can be used as a foundation for developing of any specialized cloud geospatial applications. Further research will be focused on distributing the cloud application on additional VMs, testing the scalability and availability of services.

  10. Development of a web application for water resources based on open source software

    NASA Astrophysics Data System (ADS)

    Delipetrev, Blagoj; Jonoski, Andreja; Solomatine, Dimitri P.

    2014-01-01

    This article presents research and development of a prototype web application for water resources using latest advancements in Information and Communication Technologies (ICT), open source software and web GIS. The web application has three web services for: (1) managing, presenting and storing of geospatial data, (2) support of water resources modeling and (3) water resources optimization. The web application is developed using several programming languages (PhP, Ajax, JavaScript, Java), libraries (OpenLayers, JQuery) and open source software components (GeoServer, PostgreSQL, PostGIS). The presented web application has several main advantages: it is available all the time, it is accessible from everywhere, it creates a real time multi-user collaboration platform, the programing languages code and components are interoperable and designed to work in a distributed computer environment, it is flexible for adding additional components and services and, it is scalable depending on the workload. The application was successfully tested on a case study with concurrent multi-users access.

  11. 40 CFR 63.5798 - What if I want to use, or I manufacture, an application technology (new or existing) whose...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ...: Reinforced Plastic Composites Production Calculating Organic Hap Emissions Factors for Open Molding and... description of the resin or gel coat application technology and supporting organic HAP emissions test data obtained using EPA test methods or their equivalent. The emission test data should be obtained using a...

  12. 40 CFR 63.5798 - What if I want to use, or I manufacture, an application technology (new or existing) whose...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ...: Reinforced Plastic Composites Production Calculating Organic Hap Emissions Factors for Open Molding and... description of the resin or gel coat application technology and supporting organic HAP emissions test data obtained using EPA test methods or their equivalent. The emission test data should be obtained using a...

  13. DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    An OpenStudio Measure is a script that can manipulate an OpenStudio model and associated data to apply energy conservation measures (ECMs), run supplemental simulations, or visualize simulation results. The OpenStudio software development kit (SDK) and accessibility of the Ruby scripting language makes measure authorship accessible to both software developers and energy modelers. This paper discusses the life cycle of an OpenStudio Measure from development, testing, and distribution, to application.

  14. A heterogeneous computing accelerated SCE-UA global optimization method using OpenMP, OpenCL, CUDA, and OpenACC.

    PubMed

    Kan, Guangyuan; He, Xiaoyan; Ding, Liuqian; Li, Jiren; Liang, Ke; Hong, Yang

    2017-10-01

    The shuffled complex evolution optimization developed at the University of Arizona (SCE-UA) has been successfully applied in various kinds of scientific and engineering optimization applications, such as hydrological model parameter calibration, for many years. The algorithm possesses good global optimality, convergence stability and robustness. However, benchmark and real-world applications reveal the poor computational efficiency of the SCE-UA. This research aims at the parallelization and acceleration of the SCE-UA method based on powerful heterogeneous computing technology. The parallel SCE-UA is implemented on Intel Xeon multi-core CPU (by using OpenMP and OpenCL) and NVIDIA Tesla many-core GPU (by using OpenCL, CUDA, and OpenACC). The serial and parallel SCE-UA were tested based on the Griewank benchmark function. Comparison results indicate the parallel SCE-UA significantly improves computational efficiency compared to the original serial version. The OpenCL implementation obtains the best overall acceleration results however, with the most complex source code. The parallel SCE-UA has bright prospects to be applied in real-world applications.

  15. Parameter estimation in linear models of the human operator in a closed loop with application of deterministic test signals

    NASA Technical Reports Server (NTRS)

    Vanlunteren, A.; Stassen, H. G.

    1973-01-01

    Parameter estimation techniques are discussed with emphasis on unbiased estimates in the presence of noise. A distinction between open and closed loop systems is made. A method is given based on the application of external forcing functions consisting of a sun of sinusoids; this method is thus based on the estimation of Fourier coefficients and is applicable for models with poles and zeros in open and closed loop systems.

  16. Impact of xylomethazoline on eustachian tube function in healthy participants.

    PubMed

    Meyer, Moritz F; Mikolajczak, Stefanie; Korthäuer, Christine; Jumah, Masen D; Hahn, Moritz; Grosheva, Maria; Lüers, Jan-Christoffer; Hüttenbrink, Karl-Bernd; Beutner, Dirk

    2015-06-01

    The use of decongestants is common in otitis media eustachian tube (ET) dysfunction. However, the underlying mechanism and the type of action on the complex middle ear pressure equalization system are poorly understood. Here, by use of the pressure chamber, we investigated the impact of intranasal decongestive therapy (xylomethazoline) on ET function. Thirty healthy participants (60 ears) were exposed to a predetermined profile of phases of compression and decompression in a hypobaric and hyperbaric pressure chamber. ET opening pressure, ET opening duration, ET opening frequency, and ET closing pressure were determined before and after intranasal application of xylomethazoline. A significantly higher number of ET openings (ET opening frequency) in passive equalization condition could be measured after application of decongestants than before. No significant difference could be found in the values of ET opening pressure, ET opening duration, and ET closing pressure parameters before in comparison with the values after application of xylomethazoline. We conclude that xylomethazoline might only have a minor effect during active and passive middle ear pressure equalization. Larger cohorts and targeted application of decongestants should be tested to confirm these preliminary data and to find new evidence on the effects of decongestants.

  17. Experimental demonstration of OpenFlow-enabled media ecosystem architecture for high-end applications over metro and core networks.

    PubMed

    Ntofon, Okung-Dike; Channegowda, Mayur P; Efstathiou, Nikolaos; Rashidi Fard, Mehdi; Nejabati, Reza; Hunter, David K; Simeonidou, Dimitra

    2013-02-25

    In this paper, a novel Software-Defined Networking (SDN) architecture is proposed for high-end Ultra High Definition (UHD) media applications. UHD media applications require huge amounts of bandwidth that can only be met with high-capacity optical networks. In addition, there are requirements for control frameworks capable of delivering effective application performance with efficient network utilization. A novel SDN-based Controller that tightly integrates application-awareness with network control and management is proposed for such applications. An OpenFlow-enabled test-bed demonstrator is reported with performance evaluations of advanced online and offline media- and network-aware schedulers.

  18. Cognitive Readiness Assessment and Reporting: An Open Source Mobile Framework for Operational Decision Support and Performance Improvement

    ERIC Educational Resources Information Center

    Heric, Matthew; Carter, Jenn

    2011-01-01

    Cognitive readiness (CR) and performance for operational time-critical environments are continuing points of focus for military and academic communities. In response to this need, we designed an open source interactive CR assessment application as a highly adaptive and efficient open source testing administration and analysis tool. It is capable…

  19. Irritant contact dermatitis from an ornamental Euphorbia.

    PubMed

    Worobec, S M; Hickey, T A; Kinghorn, A D; Soejarto, D D; West, D

    1981-01-01

    An ornamental succulent plant sold in many plant stores in the Chicago area has been identified as Euphorbia hermentiana Lem. Open and closed patch testing using undiluted latex from this species was performed on five Caucasian volunteers. Open testing on flexor forearms resulted in irritant follicular dermatitis, while closed testing to the flexor surfaces of both upper arms in each subject produced bullae and vesiculation with residual desquamation and hyperpigmentation. Dermatological signs persisted for over a week following latex application.

  20. Theory and Tests of Two-Phase Turbines

    NASA Technical Reports Server (NTRS)

    Elliott, D. G.

    1986-01-01

    New turbines open possibility of new types of power cycles. Report describes theoretical analysis and experimental testing of two-phase impulse turbines. Such turbines open possibility of new types of power cycles operating with extremely wet mixtures of steam and water, organic fluids, or immiscible liquids and gases. Possible applications are geothermal power, waste-heat recovery, refrigerant expansion, solar conversion, transportation, and engine-bottoming cycles.

  1. Background-Oriented Schlieren Applications in NASA Glenn Research Center's Ground Test Facilities

    NASA Technical Reports Server (NTRS)

    Clem, Michelle M.; Woike, Mark R.

    2015-01-01

    This is a presentation for an invited session at the 2015 SciTech Conference 53rd AIAA Aerospace Sciences Meeting. The presentation covers the recent applications of Background-Oriented Schlieren in NASA Glenn Research Center's ground test facilities, such as the 8x6 SWT, open jet rig, and AAPL.

  2. Perceptron Genetic to Recognize Openning Strategy Ruy Lopez

    NASA Astrophysics Data System (ADS)

    Azmi, Zulfian; Mawengkang, Herman

    2018-01-01

    The application of Perceptron method is not effective for coding on hardware based systems because it is not real time learning. With Genetic algorithm approach in calculating and searching the best weight (fitness value) system will do learning only one iteration. And the results of this analysis were tested in the case of the introduction of the opening pattern of chess Ruy Lopez. The Analysis with Perceptron Model with Algorithm Approach Genetics from group Artificial Neural Network for open Ruy Lopez. The data is processed with base open chess, with step eight a position white Pion from end open chess. Using perceptron method have many input and one output process many weight and refraction until output equal goal. Data trained and test with software Matlab and system can recognize the chess opening Ruy Lopez or Not open Ruy Lopez with Real time.

  3. Architecture Design and Experimental Platform Demonstration of Optical Network based on OpenFlow Protocol

    NASA Astrophysics Data System (ADS)

    Xing, Fangyuan; Wang, Honghuan; Yin, Hongxi; Li, Ming; Luo, Shenzi; Wu, Chenguang

    2016-02-01

    With the extensive application of cloud computing and data centres, as well as the constantly emerging services, the big data with the burst characteristic has brought huge challenges to optical networks. Consequently, the software defined optical network (SDON) that combines optical networks with software defined network (SDN), has attracted much attention. In this paper, an OpenFlow-enabled optical node employed in optical cross-connect (OXC) and reconfigurable optical add/drop multiplexer (ROADM), is proposed. An open source OpenFlow controller is extended on routing strategies. In addition, the experiment platform based on OpenFlow protocol for software defined optical network, is designed. The feasibility and availability of the OpenFlow-enabled optical nodes and the extended OpenFlow controller are validated by the connectivity test, protection switching and load balancing experiments in this test platform.

  4. Open Technology Approaches to Geospatial Interface Design

    NASA Astrophysics Data System (ADS)

    Crevensten, B.; Simmons, D.; Alaska Satellite Facility

    2011-12-01

    What problems do you not want your software developers to be solving? Choosing open technologies across the entire stack of software development-from low-level shared libraries to high-level user interaction implementations-is a way to help ensure that customized software yields innovative and valuable tools for Earth Scientists. This demonstration will review developments in web application technologies and the recurring patterns of interaction design regarding exploration and discovery of geospatial data through the Vertex: ASF's Dataportal interface, a project utilizing current open web application standards and technologies including HTML5, jQueryUI, Backbone.js and the Jasmine unit testing framework.

  5. 40 CFR 202.21 - Standard for operation under stationary test.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... sound level in excess of 88 dB(A) measured on an open site with fast meter response at 50 feet from the... applicable which generates a sound level in excess of 85 dB(A) measured on an open site with fast meter...

  6. Tuboimpedance: A New Test of Eustachian Tube Function.

    PubMed

    Smith, Matthew E; Zou, Charlie C; Blythe, Andrew J C; Tysome, James R

    2017-04-01

    Objective Eustachian tube (ET) dysfunction is most frequently caused by a failure of the ET to adequately open; however, there is currently no reliable method of assessing this. Tubomanometry has recently shown good interindividual repeatability as a measure of ET function by measuring middle ear pressure after the application of regulated nasopharyngeal pressures during swallowing. We present the first reports of a novel test: middle ear impedance measurements during standard nasopharyngeal pressure application (tuboimpedance). We assess repeatability in healthy ears and any advantages over tubomanometry. Study Design Exploratory cohort diagnosis study. Setting Tertiary referral center. Subjects Twenty screened, healthy ears (10 volunteers). Methods Tubomanometry and tuboimpedance tests were performed while individuals swallowed with applied nasopharyngeal pressures of 20, 30, 40, and 50 mbar. Eustachian tube opening detection rate and test repeatability (measured by intraclass correlation coefficient [ICC]) for immediate and delayed repeats at each pressure were compared. Results ET opening was detected more frequently using tuboimpedance, with a 100% detection rate using a nasopharyngeal pressure of 30 mbar or more, compared to 88% to 96% with tubomanometry. Detection of ET opening at 20 mbar was possible with tuboimpedance. Repeatability of both tests was mostly strong (ICC >0.7) for both immediate and delayed repeats. Repeatability for the tubomanometry R value was only fair to moderate. Conclusion Tuboimpedance may provide a repeatable measure of ET opening that is easier to perform due to lower nasopharyngeal pressures required and fewer issues with poor ear-probe sealing. Further assessment in patients with different forms of ET dysfunction is required.

  7. Magnetogama: an open schematic magnetometer

    NASA Astrophysics Data System (ADS)

    Wahyudi; Khakhim, Nurul; Kuntoro, Tri; Mardiatno, Djati; Rakhman, Afif; Setyo Handaru, Anas; Akhmad Mufaqih, Adien; Marwan Irnaka, Theodosius

    2017-09-01

    Magnetogama is an open schematic hand-assembled fluxgate magnetometer. Compared to another magnetometer, Magnetogama has more benefit concerning its price and its ease of use. Practically Magnetogama can be utilized either in land or attached to an unmanned aerial vehicle (UAV). Magnetogama was designed to give open access to a cheap and accurate alternative to magnetometer sensor. Therefore it can be used as a standard design which is directly applicable to the low-budget company or education purposes. Schematic, code and several verification tests were presented in this article ensuring its reproducibility. Magnetogama has been tested with two kind of tests: a comparison with two nearest observatories at Learmonth (LRM) and Kakadu (KDU) and the response of magnetic substance.

  8. Design and deployment of an elastic network test-bed in IHEP data center based on SDN

    NASA Astrophysics Data System (ADS)

    Zeng, Shan; Qi, Fazhi; Chen, Gang

    2017-10-01

    High energy physics experiments produce huge amounts of raw data, while because of the sharing characteristics of the network resources, there is no guarantee of the available bandwidth for each experiment which may cause link congestion problems. On the other side, with the development of cloud computing technologies, IHEP have established a cloud platform based on OpenStack which can ensure the flexibility of the computing and storage resources, and more and more computing applications have been deployed on virtual machines established by OpenStack. However, under the traditional network architecture, network capability can’t be required elastically, which becomes the bottleneck of restricting the flexible application of cloud computing. In order to solve the above problems, we propose an elastic cloud data center network architecture based on SDN, and we also design a high performance controller cluster based on OpenDaylight. In the end, we present our current test results.

  9. Toward open set recognition.

    PubMed

    Scheirer, Walter J; de Rezende Rocha, Anderson; Sapkota, Archana; Boult, Terrance E

    2013-07-01

    To date, almost all experimental evaluations of machine learning-based recognition algorithms in computer vision have taken the form of "closed set" recognition, whereby all testing classes are known at training time. A more realistic scenario for vision applications is "open set" recognition, where incomplete knowledge of the world is present at training time, and unknown classes can be submitted to an algorithm during testing. This paper explores the nature of open set recognition and formalizes its definition as a constrained minimization problem. The open set recognition problem is not well addressed by existing algorithms because it requires strong generalization. As a step toward a solution, we introduce a novel "1-vs-set machine," which sculpts a decision space from the marginal distances of a 1-class or binary SVM with a linear kernel. This methodology applies to several different applications in computer vision where open set recognition is a challenging problem, including object recognition and face verification. We consider both in this work, with large scale cross-dataset experiments performed over the Caltech 256 and ImageNet sets, as well as face matching experiments performed over the Labeled Faces in the Wild set. The experiments highlight the effectiveness of machines adapted for open set evaluation compared to existing 1-class and binary SVMs for the same tasks.

  10. An overview of the DII-HEP OpenStack based CMS data analysis

    NASA Astrophysics Data System (ADS)

    Osmani, L.; Tarkoma, S.; Eerola, P.; Komu, M.; Kortelainen, M. J.; Kraemer, O.; Lindén, T.; Toor, S.; White, J.

    2015-05-01

    An OpenStack based private cloud with the Cluster File System has been built and used with both CMS analysis and Monte Carlo simulation jobs in the Datacenter Indirection Infrastructure for Secure High Energy Physics (DII-HEP) project. On the cloud we run the ARC middleware that allows running CMS applications without changes on the job submission side. Our test results indicate that the adopted approach provides a scalable and resilient solution for managing resources without compromising on performance and high availability. To manage the virtual machines (VM) dynamically in an elastic fasion, we are testing the EMI authorization service (Argus) and the Execution Environment Service (Argus-EES). An OpenStackplugin has been developed for Argus-EES. The Host Identity Protocol (HIP) has been designed for mobile networks and it provides a secure method for IP multihoming. HIP separates the end-point identifier and locator role for IP address which increases the network availability for the applications. Our solution leverages HIP for traffic management. This presentation gives an update on the status of the work and our lessons learned in creating an OpenStackbased cloud for HEP.

  11. 76 FR 28967 - Columbia Gas Transmission, LLC; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-19

    ... authority to continue to test and evaluate its Coco C storage field located in Kanawha County, West Virginia... field to develop further storage services, all as more fully set forth in the application which is on file with the Commission and open to public inspection. Any questions regarding this application should...

  12. Extrapolating the Trends of Test Drop Data with Opening Shock Factor Calculations: the Case of the Orion Main and Drogue Parachutes Inflating to 1st Reefed Stage

    NASA Technical Reports Server (NTRS)

    Potvin, Jean; Ray, Eric

    2017-01-01

    We describe a new calculation of the opening shock factor C (sub k) characterizing the inflation performance of NASA's Orion spacecraft main and drogue parachutes opening under a reefing constraint (1st stage reefing), as currently tested in the Capsule Parachute Assembly System (CPAS) program. This calculation is based on an application of the Momentum-Impulse Theorem at low mass ratio (R (sub m) is less than 10 (sup -1)) and on an earlier analysis of the opening performance of drogues decelerating point masses and inflating along horizontal trajectories. Herein we extend the reach of the Theorem to include the effects of payload drag and gravitational impulse during near-vertical motion - both important pre-requisites for CPAS parachute analysis. The result is a family of C (sub k) versus R (sub m) curves which can be used for extrapolating beyond the drop-tested envelope. The paper proves this claim in the case of the CPAS Mains and Drogues opening while trailing either a Parachute Compartment Drop Test Vehicle or a Parachute Test Vehicle (an Orion capsule boiler plate). It is seen that in all cases the values of the opening shock factor can be extrapolated over a range in mass ratio that is at least twice that of the test drop data.

  13. REPORT OF THE QUALIFICATION TESTING OF SNAP 10A FUSISTORS

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Holtwick, J.S. III; Nowell, V.P.

    1963-07-31

    Qualification testing of SNAP 10A fusistors was performed. Test operations included: visual inspection, insulation resistance, dielectric strength, and d-c resistance testing prior to subjecting the fusisters to environmental testing; opening-time testing prior to, during, and following vacuum and temperature testing; and insulation resistance, dielectric strength, and d-c resistance testing following environmental applications of temperature, vacuum, and sinusoidal vibration. (auth)

  14. Safety Evaluation of Self-assembling Peptide Gel after Intracranial Administration to Rats Using the Open Field Test.

    PubMed

    Tsunoda, Masashi; Sugaya, Chiemi; Sugiura, Yumiko; Nagai, Yusuke; Sakanishi, Kotaro

    2016-01-01

    Self-assembling peptides have been developed as clinical materials, which could scaffold to regenerate nerve cells and hemostatic materials in vivo. However, there has not been enough information for their in vivo application. The safety of self-assembling peptides for the application on the brain was examined using behavioral tests for each rat in this study. Self-assembling peptide gel was administered to the surface of the brain at a volume of 20 µL at 1.5%. After 2 months, the open field test and the prepulse inhibition (PPI) test were performed. There were no significant differences between the peptide gel and the control groups in locomotor distances and in %PPIs in the PPI test. The mean values of the percentage of time the rats stayed in the central area of the open field during the first 5 min and instances of center rearing or face washing in the peptide gel group were significantly higher than those in the control. There were amorphous substance in the subarachnoid region, and infiltrations of mononuclear cells were also observed in the self-assembling peptide gel group. Although the meaning of the effects observed in this study was not fully elucidated, the self-assembling gel produced marginal but significant behavioral and histological effects.

  15. Multicenter clinical trial on a permanent hair dye containing paratoluenediamine.

    PubMed

    Foti, Caterina; Balato, Nicola; Cristaudo, Antonio; Patruno, Cataldo; Pigatto, Paolo; Ambrifi, Marina; Bufano, Tamara; Damiani, Giovanni; De Rocco, Mariagrazia; Diani, Marco; Napolitano, Maddalena; Romita, Paolo

    2018-08-01

    Adverse reactions to hair dyes are frequent and usually caused by sensitization to paraphenylenediamine (PPD). The aim of the study was to evaluate the tolerability of a PPD-free permanent hair dye (Shine On, BioNike, Milan, Italy) containing paratoluenediamine (PTD) in a group of subjects sensitized to PPD. The trial, which carried out at four dermatology centers, included subjects sensitized to PPD that turned out negative to patch testing to PTD. The subjects underwent to an open test consisting in the application of two hair dye colors of the product under examination. Finally, subjects who were negative upon the open test were offered to undergo the usage test with the dye, with dermatological evaluations carried out 48 and 96 hours after product application. Sixty subjects were enrolled. They underwent the open test with two shades of dyes: "color 1 - black," the dye color with the highest concentration of color intermediates, and "color 7.3 - golden blonde," the dye color with the highest number of chemically different color intermediates. No reactions occurred with "color 7.3 - golden blonde," while 3 cases (3 out of 60) showed erythema and edema reactions to color 1. The hair dye usage test was negative for all the 21 subjects that were enrolled. The hair dye evaluated in this study (Shine On, BioNike) can be a valid alternative for subjects sensitized to PPD.

  16. Wireless access to a pharmaceutical database: a demonstrator for data driven Wireless Application Protocol (WAP) applications in medical information processing.

    PubMed

    Schacht Hansen, M; Dørup, J

    2001-01-01

    The Wireless Application Protocol technology implemented in newer mobile phones has built-in facilities for handling much of the information processing needed in clinical work. To test a practical approach we ported a relational database of the Danish pharmaceutical catalogue to Wireless Application Protocol using open source freeware at all steps. We used Apache 1.3 web software on a Linux server. Data containing the Danish pharmaceutical catalogue were imported from an ASCII file into a MySQL 3.22.32 database using a Practical Extraction and Report Language script for easy update of the database. Data were distributed in 35 interrelated tables. Each pharmaceutical brand name was given its own card with links to general information about the drug, active substances, contraindications etc. Access was available through 1) browsing therapeutic groups and 2) searching for a brand name. The database interface was programmed in the server-side scripting language PHP3. A free, open source Wireless Application Protocol gateway to a pharmaceutical catalogue was established to allow dial-in access independent of commercial Wireless Application Protocol service providers. The application was tested on the Nokia 7110 and Ericsson R320s cellular phones. We have demonstrated that Wireless Application Protocol-based access to a dynamic clinical database can be established using open source freeware. The project opens perspectives for a further integration of Wireless Application Protocol phone functions in clinical information processing: Global System for Mobile communication telephony for bilateral communication, asynchronous unilateral communication via e-mail and Short Message Service, built-in calculator, calendar, personal organizer, phone number catalogue and Dictaphone function via answering machine technology. An independent Wireless Application Protocol gateway may be placed within hospital firewalls, which may be an advantage with respect to security. However, if Wireless Application Protocol phones are to become effective tools for physicians, special attention must be paid to the limitations of the devices. Input tools of Wireless Application Protocol phones should be improved, for instance by increased use of speech control.

  17. Wireless access to a pharmaceutical database: A demonstrator for data driven Wireless Application Protocol applications in medical information processing

    PubMed Central

    Hansen, Michael Schacht

    2001-01-01

    Background The Wireless Application Protocol technology implemented in newer mobile phones has built-in facilities for handling much of the information processing needed in clinical work. Objectives To test a practical approach we ported a relational database of the Danish pharmaceutical catalogue to Wireless Application Protocol using open source freeware at all steps. Methods We used Apache 1.3 web software on a Linux server. Data containing the Danish pharmaceutical catalogue were imported from an ASCII file into a MySQL 3.22.32 database using a Practical Extraction and Report Language script for easy update of the database. Data were distributed in 35 interrelated tables. Each pharmaceutical brand name was given its own card with links to general information about the drug, active substances, contraindications etc. Access was available through 1) browsing therapeutic groups and 2) searching for a brand name. The database interface was programmed in the server-side scripting language PHP3. Results A free, open source Wireless Application Protocol gateway to a pharmaceutical catalogue was established to allow dial-in access independent of commercial Wireless Application Protocol service providers. The application was tested on the Nokia 7110 and Ericsson R320s cellular phones. Conclusions We have demonstrated that Wireless Application Protocol-based access to a dynamic clinical database can be established using open source freeware. The project opens perspectives for a further integration of Wireless Application Protocol phone functions in clinical information processing: Global System for Mobile communication telephony for bilateral communication, asynchronous unilateral communication via e-mail and Short Message Service, built-in calculator, calendar, personal organizer, phone number catalogue and Dictaphone function via answering machine technology. An independent Wireless Application Protocol gateway may be placed within hospital firewalls, which may be an advantage with respect to security. However, if Wireless Application Protocol phones are to become effective tools for physicians, special attention must be paid to the limitations of the devices. Input tools of Wireless Application Protocol phones should be improved, for instance by increased use of speech control. PMID:11720946

  18. ReSTful OSGi Web Applications Tutorial

    NASA Technical Reports Server (NTRS)

    Shams, Khawaja; Norris, Jeff

    2008-01-01

    This slide presentation accompanies a tutorial on the ReSTful (Representational State Transfer) web application. Using Open Services Gateway Initiative (OSGi), ReST uses HTTP protocol to enable developers to offer services to a diverse variety of clients: from shell scripts to sophisticated Java application suites. It also uses Eclipse for the rapid development, the Eclipse debugger, the test application, and the ease of export to production servers.

  19. Environmental Monitoring Curriculum System and Application-Oriented Training

    ERIC Educational Resources Information Center

    Wang, Jing-Ping; Wang, Xin-Hong

    2016-01-01

    Through building the environmental monitoring curriculum system for application-oriented talents, the comprehensive design and practice were constructed from the syllabus, textbooks, web-based courses, top-quality courses, test paper bank, open laboratory and scientific research etc. The aims are to promote environmental science professional,…

  20. Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Test act system validation

    NASA Technical Reports Server (NTRS)

    1985-01-01

    The primary objective of the Test Active Control Technology (ACT) System laboratory tests was to verify and validate the system concept, hardware, and software. The initial lab tests were open loop hardware tests of the Test ACT System as designed and built. During the course of the testing, minor problems were uncovered and corrected. Major software tests were run. The initial software testing was also open loop. These tests examined pitch control laws, wing load alleviation, signal selection/fault detection (SSFD), and output management. The Test ACT System was modified to interface with the direct drive valve (DDV) modules. The initial testing identified problem areas with DDV nonlinearities, valve friction induced limit cycling, DDV control loop instability, and channel command mismatch. The other DDV issue investigated was the ability to detect and isolate failures. Some simple schemes for failure detection were tested but were not completely satisfactory. The Test ACT System architecture continues to appear promising for ACT/FBW applications in systems that must be immune to worst case generic digital faults, and be able to tolerate two sequential nongeneric faults with no reduction in performance. The challenge in such an implementation would be to keep the analog element sufficiently simple to achieve the necessary reliability.

  1. Comparison of Occlusive and Open Application in a Psoriasis Plaque Test Design, Exemplarily Using Investigations of Mapracorat 0.1% Ointment versus Vehicle and Reference Drugs.

    PubMed

    Wigger-Alberti, Walter; Williams, Ragna; von Mackensen, Yi-Ling; Hoffman-Wecker, Maciej; Grossmann, Ulrike; Staedtler, Gerald; Nkulikiyinka, Richard; Shakery, Kaweh

    2017-01-01

    Psoriasis plaque tests (PPTs) are important tools in the early phases of antipsoriatic drug development. Two distinct PPT design variants (open vs. occluded drug application) are commonly used, but no previous work has aimed to directly compare and contrast their performance. We compared the antipsoriatic efficacy of mapracorat 0.1% ointment and reference drugs reported in 2 separate studies, representing open and occluded PPT designs. The drug effect size was measured by sonography (mean change in echo-poor band thickness), chromametry, and standardized clinical assessment. Antipsoriatic effects were detectable for the study drugs in both occluded and open PPTs. Differences between the potency of antipsoriatic drugs and vehicle were observable. The total antipsoriatic effect size appeared to be higher in the occluded PPT than the open PPT, despite the shorter treatment duration (2 vs. 4 weeks). Effect dynamics over time revealed greater differences between some study drugs in the open PPT compared to the occluded PPT. Taking the higher technical challenges for the open PPT into account, we recommend the occluded PPT as a standard screening setting in early drug development. In special cases, considering certain drug aspects or study objectives that would require procedural adaptations, an open PPT could be the better-suited design. Finally, both PPT models show clear advantages: classification as phase I studies, small number of psoriatic subjects, relatively short study duration, excellent discrimination between compounds and concentrations, parallel measurement of treatment response, and go/no go decisions very early in clinical development. © 2017 S. Karger AG, Basel.

  2. Evaluation of Three Approaches for Assessing Adherence to Vaginal Gel Application in Clinical Trials

    PubMed Central

    van der Straten, Ariane; Cheng, Helen; Mensch, Barbara; Friedland, Barbara; Katzen, Lauren; Littlefield, Sarah; Buckley, Niall; Espinoza, Lilia; Keller, Marla J.; Herold, Betsy C.; Einstein, Mark H.

    2014-01-01

    Background: Accurate measurement of adherence to product use is an ongoing challenge in microbicide trials. Methods: We compared adherence estimates using two applicator tests (a dye stain assay [DSA] and an ultraviolet light assay [UVA]), the Wisebag (an applicator container that electronically tracks container openings), and self-reported adherence (ability, frequency, and percent missed doses). Healthy, HIV-negative, non-pregnant US women aged 23 to 45 received a Wisebag and 32 applicators filled with placebo gel, were instructed to insert one applicator daily for 30 days, returned the Wisebag and all applicators, and completed an exit interview. Emptied applicators were tested by UVA and then DSA, and scored by two blinded readers. Positive and negative controls were randomly included in applicator batches. Results: Among 42 women enrolled, 39 completed the study. DSA and UVA yielded similar sensitivity (97% and 95%) and specificity (79% and 79%). Two participants had fully inoperable Wisebags and nine had partially inoperable Wisebags. The proportion of participants considered to have high adherence (≥80%) varied: 43% (Wisebag), 46% (UVA), 49% (DSA), and 62% to 82% (self-reports). For estimating high adherence, Wisebag had a sensitivity of 76% (95% CI, 50% to 93%) and a specificity of 85% (95% CI, 62% to 97%) compared with DSA. Although 28% of participants reported forgetting to open the Wisebag daily, 59% said it helped them remember gel use. Conclusions: DSA and UVA performed similarly. Compared with these tests, self-reports overestimated and Wisebag underestimated adherence. Although Wisebag may encourage gel use, the applicator tests currently appear more useful for measuring use in clinical trials. PMID:24220357

  3. Performance evaluation of OpenFOAM on many-core architectures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brzobohatý, Tomáš; Říha, Lubomír; Karásek, Tomáš, E-mail: tomas.karasek@vsb.cz

    In this article application of Open Source Field Operation and Manipulation (OpenFOAM) C++ libraries for solving engineering problems on many-core architectures is presented. Objective of this article is to present scalability of OpenFOAM on parallel platforms solving real engineering problems of fluid dynamics. Scalability test of OpenFOAM is performed using various hardware and different implementation of standard PCG and PBiCG Krylov iterative methods. Speed up of various implementations of linear solvers using GPU and MIC accelerators are presented in this paper. Numerical experiments of 3D lid-driven cavity flow for several cases with various number of cells are presented.

  4. Refining Success and Dropout in Massive Open Online Courses Based on the Intention-Behavior Gap

    ERIC Educational Resources Information Center

    Henderikx, Maartje A.; Kreijns, Karel; Kalz, Marco

    2017-01-01

    In this paper we present an alternative typology for determining success and dropout in massive open online courses (MOOCs). This typology takes the perspectives of MOOC-takers into account and is based on the their intentions and subsequent behaviour. An explorative study using two MOOCs was carried out to test the applicability of the typology.…

  5. Open-set speaker identification with diverse-duration speech data

    NASA Astrophysics Data System (ADS)

    Karadaghi, Rawande; Hertlein, Heinz; Ariyaeeinia, Aladdin

    2015-05-01

    The concern in this paper is an important category of applications of open-set speaker identification in criminal investigation, which involves operating with short and varied duration speech. The study presents investigations into the adverse effects of such an operating condition on the accuracy of open-set speaker identification, based on both GMMUBM and i-vector approaches. The experiments are conducted using a protocol developed for the identification task, based on the NIST speaker recognition evaluation corpus of 2008. In order to closely cover the real-world operating conditions in the considered application area, the study includes experiments with various combinations of training and testing data duration. The paper details the characteristics of the experimental investigations conducted and provides a thorough analysis of the results obtained.

  6. Tone and Broadband Noise Separation from Acoustic Data of a Scale-Model Counter-Rotating Open Rotor

    NASA Technical Reports Server (NTRS)

    Sree, David; Stephens, David B.

    2014-01-01

    Renewed interest in contra-rotating open rotor technology for aircraft propulsion application has prompted the development of advanced diagnostic tools for better design and improved acoustical performance. In particular, the determination of tonal and broadband components of open rotor acoustic spectra is essential for properly assessing the noise control parameters and also for validating the open rotor noise simulation codes. The technique of phase averaging has been employed to separate the tone and broadband components from a single rotor, but this method does not work for the two-shaft contra-rotating open rotor. A new signal processing technique was recently developed to process the contra-rotating open rotor acoustic data. The technique was first tested using acoustic data taken of a hobby aircraft open rotor propeller, and reported previously. The intent of the present work is to verify and validate the applicability of the new technique to a realistic one-fifth scale open rotor model which has 12 forward and 10 aft contra-rotating blades operating at realistic forward flight Mach numbers and tip speeds. The results and discussions of that study are presented in this paper.

  7. Tone and Broadband Noise Separation from Acoustic Data of a Scale-Model Contra-Rotating Open Rotor

    NASA Technical Reports Server (NTRS)

    Sree, Dave; Stephens, David B.

    2014-01-01

    Renewed interest in contra-rotating open rotor technology for aircraft propulsion application has prompted the development of advanced diagnostic tools for better design and improved acoustical performance. In particular, the determination of tonal and broadband components of open rotor acoustic spectra is essential for properly assessing the noise control parameters and also for validating the open rotor noise simulation codes. The technique of phase averaging has been employed to separate the tone and broadband components from a single rotor, but this method does not work for the two-shaft contra-rotating open rotor. A new signal processing technique was recently developed to process the contra-rotating open rotor acoustic data. The technique was first tested using acoustic data taken of a hobby aircraft open rotor propeller, and reported previously. The intent of the present work is to verify and validate the applicability of the new technique to a realistic one-fifth scale open rotor model which has 12 forward and 10 aft contra-rotating blades operating at realistic forward flight Mach numbers and tip speeds. The results and discussions of that study are presented in this paper.

  8. Kokkos: Enabling manycore performance portability through polymorphic memory access patterns

    DOE PAGES

    Carter Edwards, H.; Trott, Christian R.; Sunderland, Daniel

    2014-07-22

    The manycore revolution can be characterized by increasing thread counts, decreasing memory per thread, and diversity of continually evolving manycore architectures. High performance computing (HPC) applications and libraries must exploit increasingly finer levels of parallelism within their codes to sustain scalability on these devices. We found that a major obstacle to performance portability is the diverse and conflicting set of constraints on memory access patterns across devices. Contemporary portable programming models address manycore parallelism (e.g., OpenMP, OpenACC, OpenCL) but fail to address memory access patterns. The Kokkos C++ library enables applications and domain libraries to achieve performance portability on diversemore » manycore architectures by unifying abstractions for both fine-grain data parallelism and memory access patterns. In this paper we describe Kokkos’ abstractions, summarize its application programmer interface (API), present performance results for unit-test kernels and mini-applications, and outline an incremental strategy for migrating legacy C++ codes to Kokkos. Furthermore, the Kokkos library is under active research and development to incorporate capabilities from new generations of manycore architectures, and to address a growing list of applications and domain libraries.« less

  9. 40 CFR 63.5798 - What if I want to use, or I manufacture, an application technology (new or existing) whose...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... Pollutants: Reinforced Plastic Composites Production Calculating Organic Hap Emissions Factors for Open... organic HAP emissions test data obtained using EPA test methods or their equivalent. The emission test data should be obtained using a range of resin or gel coat HAP contents to demonstrate the...

  10. 40 CFR 63.5798 - What if I want to use, or I manufacture, an application technology (new or existing) whose...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Pollutants: Reinforced Plastic Composites Production Calculating Organic Hap Emissions Factors for Open... organic HAP emissions test data obtained using EPA test methods or their equivalent. The emission test data should be obtained using a range of resin or gel coat HAP contents to demonstrate the...

  11. 40 CFR 63.5798 - What if I want to use, or I manufacture, an application technology (new or existing) whose...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... Pollutants: Reinforced Plastic Composites Production Calculating Organic Hap Emissions Factors for Open... organic HAP emissions test data obtained using EPA test methods or their equivalent. The emission test data should be obtained using a range of resin or gel coat HAP contents to demonstrate the...

  12. Modelling of Operative Report Documents for Data Integration into an openEHR-Based Enterprise Data Warehouse.

    PubMed

    Haarbrandt, Birger; Wilschko, Andreas; Marschollek, Michael

    2016-01-01

    In order to integrate operative report documents from two operating room management systems into a data warehouse, we investigated the application of the two-level modelling approach of openEHR to create a shared data model. Based on the systems' analyses, a template consisting of 13 archetypes has been developed. Of these 13 archetypes, 3 have been obtained from the international archetype repository of the openEHR foundation. The remaining 10 archetypes have been newly created. The template was evaluated by an application system expert and through conducting a first test mapping of real-world data from one of the systems. The evaluation showed that by using the two-level modelling approach of openEHR, we succeeded to represent an integrated and shared information model for operative report documents. More research is needed to learn about the limitations of this approach in other data integration scenarios.

  13. 12 CFR Supplement I to Part 202 - Official Staff Interpretations

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ... an application on the basis of incompleteness.) 2(g) Business credit. 1. Definition. The test for deciding whether a transaction qualifies as business credit is one of primary purpose. For example, an open... becomes available. 4. Effects test and disparate treatment. An empirically derived, demonstrably and...

  14. 12 CFR Supplement I to Part 202 - Official Staff Interpretations

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... an application on the basis of incompleteness.) 2(g) Business credit. 1. Definition. The test for deciding whether a transaction qualifies as business credit is one of primary purpose. For example, an open... becomes available. 4. Effects test and disparate treatment. An empirically derived, demonstrably and...

  15. 12 CFR Supplement I to Part 202 - Official Staff Interpretations

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... an application on the basis of incompleteness.) 2(g) Business credit. 1. Definition. The test for deciding whether a transaction qualifies as business credit is one of primary purpose. For example, an open... becomes available. 4. Effects test and disparate treatment. An empirically derived, demonstrably and...

  16. 12 CFR Supplement I to Part 202 - Official Staff Interpretations

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ... an application on the basis of incompleteness.) 2(g) Business credit. 1. Definition. The test for deciding whether a transaction qualifies as business credit is one of primary purpose. For example, an open... becomes available. 4. Effects test and disparate treatment. An empirically derived, demonstrably and...

  17. DEVELOPMENT AND APPLICATION OF PROTOCOLS FOR EVALUATION OF OIL SPILL BIOREMEDIATION (RESEARCH BRIEF)

    EPA Science Inventory

    Protocols were developed and evaluated to assess the efficacy and environmental safety of commercial oil spill bioremediation agents (CBAs). Test systems that simulate oil slicks on open water or oiled sandy beaches were used to test the effectiveness of CBAs. Gravimetric and gas...

  18. Mapping chemicals in air using an environmental CAT scanning system: evaluation of algorithms

    NASA Astrophysics Data System (ADS)

    Samanta, A.; Todd, L. A.

    A new technique is being developed which creates near real-time maps of chemical concentrations in air for environmental and occupational environmental applications. This technique, we call Environmental CAT Scanning, combines the real-time measuring technique of open-path Fourier transform infrared spectroscopy with the mapping capabilitites of computed tomography to produce two-dimensional concentration maps. With this system, a network of open-path measurements is obtained over an area; measurements are then processed using a tomographic algorithm to reconstruct the concentrations. This research focussed on the process of evaluating and selecting appropriate reconstruction algorithms, for use in the field, by using test concentration data from both computer simultation and laboratory chamber studies. Four algorithms were tested using three types of data: (1) experimental open-path data from studies that used a prototype opne-path Fourier transform/computed tomography system in an exposure chamber; (2) synthetic open-path data generated from maps created by kriging point samples taken in the chamber studies (in 1), and; (3) synthetic open-path data generated using a chemical dispersion model to create time seires maps. The iterative algorithms used to reconstruct the concentration data were: Algebraic Reconstruction Technique without Weights (ART1), Algebraic Reconstruction Technique with Weights (ARTW), Maximum Likelihood with Expectation Maximization (MLEM) and Multiplicative Algebraic Reconstruction Technique (MART). Maps were evaluated quantitatively and qualitatively. In general, MART and MLEM performed best, followed by ARTW and ART1. However, algorithm performance varied under different contaminant scenarios. This study showed the importance of using a variety of maps, particulary those generated using dispersion models. The time series maps provided a more rigorous test of the algorithms and allowed distinctions to be made among the algorithms. A comprehensive evaluation of algorithms, for the environmental application of tomography, requires the use of a battery of test concentration data before field implementation, which models reality and tests the limits of the algorithms.

  19. SlicerRT: radiation therapy research toolkit for 3D Slicer.

    PubMed

    Pinter, Csaba; Lasso, Andras; Wang, An; Jaffray, David; Fichtinger, Gabor

    2012-10-01

    Interest in adaptive radiation therapy research is constantly growing, but software tools available for researchers are mostly either expensive, closed proprietary applications, or free open-source packages with limited scope, extensibility, reliability, or user support. To address these limitations, we propose SlicerRT, a customizable, free, and open-source radiation therapy research toolkit. SlicerRT aspires to be an open-source toolkit for RT research, providing fast computations, convenient workflows for researchers, and a general image-guided therapy infrastructure to assist clinical translation of experimental therapeutic approaches. It is a medium into which RT researchers can integrate their methods and algorithms, and conduct comparative testing. SlicerRT was implemented as an extension for the widely used 3D Slicer medical image visualization and analysis application platform. SlicerRT provides functionality specifically designed for radiation therapy research, in addition to the powerful tools that 3D Slicer offers for visualization, registration, segmentation, and data management. The feature set of SlicerRT was defined through consensus discussions with a large pool of RT researchers, including both radiation oncologists and medical physicists. The development processes used were similar to those of 3D Slicer to ensure software quality. Standardized mechanisms of 3D Slicer were applied for documentation, distribution, and user support. The testing and validation environment was configured to automatically launch a regression test upon each software change and to perform comparison with ground truth results provided by other RT applications. Modules have been created for importing and loading DICOM-RT data, computing and displaying dose volume histograms, creating accumulated dose volumes, comparing dose volumes, and visualizing isodose lines and surfaces. The effectiveness of using 3D Slicer with the proposed SlicerRT extension for radiation therapy research was demonstrated on multiple use cases. A new open-source software toolkit has been developed for radiation therapy research. SlicerRT can import treatment plans from various sources into 3D Slicer for visualization, analysis, comparison, and processing. The provided algorithms are extensively tested and they are accessible through a convenient graphical user interface as well as a flexible application programming interface.

  20. 75 FR 33289 - Columbia Gas Transmission, LLC; Notice of Application

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-06-11

    ... fields to develop further storage services, as more fully set forth in the application which is open to... certificate of public convenience and necessity, seeking authority to extend the test and evaluation period at Columbia's Lanham, Terra Alta, and Terra Alta South storage fields, all located in West Virginia.\\1...

  1. Ease of opening of blistered solid dosage forms in a senior citizens target group.

    PubMed

    Braun-Münker, Myriam; Ecker, Felix

    2016-10-30

    Blisters differing in design and handling are established as packaging material for solid dosage forms. The ease of opening of blisters influences application and patient's compliance. In this study the influence of visibility and movability of solid dosage forms in blister packaging on both, easy opening and patient's satisfaction, were investigated by target group testing according to ONR CEN/TS 15945. For each testing 20 participants in the age of 65-80 years were recruited randomly. They opened the blisters on realistic terms without any auxiliary devices. Video documentation of the hands' movements was recorded to analyze the opening procedure. To show the influence of visibility of the dosage form in the blister, capsules size 1 were packed in transparent and opaque blisters. A moderate influence of the visibility on both, the ease of opening and patient satisfaction, was observed. A second study dealt with the movability of solid dosage forms in blisters. Therefore, three different sizes of tablets with similar shapes were packed in identical cavities. Limited movability was found as major criterion on effectiveness and effectivity of opening as well as on satisfaction with the opening procedure. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Your Personal Analysis Toolkit - An Open Source Solution

    NASA Astrophysics Data System (ADS)

    Mitchell, T.

    2009-12-01

    Open source software is commonly known for its web browsers, word processors and programming languages. However, there is a vast array of open source software focused on geographic information management and geospatial application building in general. As geo-professionals, having easy access to tools for our jobs is crucial. Open source software provides the opportunity to add a tool to your tool belt and carry it with you for your entire career - with no license fees, a supportive community and the opportunity to test, adopt and upgrade at your own pace. OSGeo is a US registered non-profit representing more than a dozen mature geospatial data management applications and programming resources. Tools cover areas such as desktop GIS, web-based mapping frameworks, metadata cataloging, spatial database analysis, image processing and more. Learn about some of these tools as they apply to AGU members, as well as how you can join OSGeo and its members in getting the job done with powerful open source tools. If you haven't heard of OSSIM, MapServer, OpenLayers, PostGIS, GRASS GIS or the many other projects under our umbrella - then you need to hear this talk. Invest in yourself - use open source!

  3. SediFoam: A general-purpose, open-source CFD-DEM solver for particle-laden flow with emphasis on sediment transport

    NASA Astrophysics Data System (ADS)

    Sun, Rui; Xiao, Heng

    2016-04-01

    With the growth of available computational resource, CFD-DEM (computational fluid dynamics-discrete element method) becomes an increasingly promising and feasible approach for the study of sediment transport. Several existing CFD-DEM solvers are applied in chemical engineering and mining industry. However, a robust CFD-DEM solver for the simulation of sediment transport is still desirable. In this work, the development of a three-dimensional, massively parallel, and open-source CFD-DEM solver SediFoam is detailed. This solver is built based on open-source solvers OpenFOAM and LAMMPS. OpenFOAM is a CFD toolbox that can perform three-dimensional fluid flow simulations on unstructured meshes; LAMMPS is a massively parallel DEM solver for molecular dynamics. Several validation tests of SediFoam are performed using cases of a wide range of complexities. The results obtained in the present simulations are consistent with those in the literature, which demonstrates the capability of SediFoam for sediment transport applications. In addition to the validation test, the parallel efficiency of SediFoam is studied to test the performance of the code for large-scale and complex simulations. The parallel efficiency tests show that the scalability of SediFoam is satisfactory in the simulations using up to O(107) particles.

  4. Continuous integration for concurrent MOOSE framework and application development on GitHub

    DOE PAGES

    Slaughter, Andrew E.; Peterson, John W.; Gaston, Derek R.; ...

    2015-11-20

    For the past several years, Idaho National Laboratory’s MOOSE framework team has employed modern software engineering techniques (continuous integration, joint application/framework source code repos- itories, automated regression testing, etc.) in developing closed-source multiphysics simulation software (Gaston et al., Journal of Open Research Software vol. 2, article e10, 2014). In March 2014, the MOOSE framework was released under an open source license on GitHub, significantly expanding and diversifying the pool of current active and potential future contributors on the project. Despite this recent growth, the same philosophy of concurrent framework and application development continues to guide the project’s development roadmap. Severalmore » specific practices, including techniques for managing multiple repositories, conducting automated regression testing, and implementing a cascading build process are discussed in this short paper. Furthermore, special attention is given to describing the manner in which these practices naturally synergize with the GitHub API and GitHub-specific features such as issue tracking, Pull Requests, and project forks.« less

  5. Continuous integration for concurrent MOOSE framework and application development on GitHub

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Slaughter, Andrew E.; Peterson, John W.; Gaston, Derek R.

    For the past several years, Idaho National Laboratory’s MOOSE framework team has employed modern software engineering techniques (continuous integration, joint application/framework source code repos- itories, automated regression testing, etc.) in developing closed-source multiphysics simulation software (Gaston et al., Journal of Open Research Software vol. 2, article e10, 2014). In March 2014, the MOOSE framework was released under an open source license on GitHub, significantly expanding and diversifying the pool of current active and potential future contributors on the project. Despite this recent growth, the same philosophy of concurrent framework and application development continues to guide the project’s development roadmap. Severalmore » specific practices, including techniques for managing multiple repositories, conducting automated regression testing, and implementing a cascading build process are discussed in this short paper. Furthermore, special attention is given to describing the manner in which these practices naturally synergize with the GitHub API and GitHub-specific features such as issue tracking, Pull Requests, and project forks.« less

  6. SCSI Communication Test Bus

    NASA Technical Reports Server (NTRS)

    Hua, Chanh V.; D'Ambrose, John J.; Jaworski, Richard C.; Halula, Elaine M.; Thornton, David N.; Heligman, Robert L.; Turner, Michael R.

    1990-01-01

    Small Computer System Interface (SCSI) communication test bus provides high-data-rate, standard interconnection enabling communication among International Business Machines (IBM) Personal System/2 Micro Channel, other devices connected to Micro Channel, test equipment, and host computer. Serves primarily as nonintrusive input/output attachment to PS/2 Micro Channel bus, providing rapid communication for debugger. Opens up possibility of using debugger in real-time applications.

  7. mdFoam+: Advanced molecular dynamics in OpenFOAM

    NASA Astrophysics Data System (ADS)

    Longshaw, S. M.; Borg, M. K.; Ramisetti, S. B.; Zhang, J.; Lockerby, D. A.; Emerson, D. R.; Reese, J. M.

    2018-03-01

    This paper introduces mdFoam+, which is an MPI parallelised molecular dynamics (MD) solver implemented entirely within the OpenFOAM software framework. It is open-source and released under the same GNU General Public License (GPL) as OpenFOAM. The source code is released as a publicly open software repository that includes detailed documentation and tutorial cases. Since mdFoam+ is designed entirely within the OpenFOAM C++ object-oriented framework, it inherits a number of key features. The code is designed for extensibility and flexibility, so it is aimed first and foremost as an MD research tool, in which new models and test cases can be developed and tested rapidly. Implementing mdFoam+ in OpenFOAM also enables easier development of hybrid methods that couple MD with continuum-based solvers. Setting up MD cases follows the standard OpenFOAM format, as mdFoam+ also relies upon the OpenFOAM dictionary-based directory structure. This ensures that useful pre- and post-processing capabilities provided by OpenFOAM remain available even though the fully Lagrangian nature of an MD simulation is not typical of most OpenFOAM applications. Results show that mdFoam+ compares well to another well-known MD code (e.g. LAMMPS) in terms of benchmark problems, although it also has additional functionality that does not exist in other open-source MD codes.

  8. Hypersonic simulations using open-source CFD and DSMC solvers

    NASA Astrophysics Data System (ADS)

    Casseau, V.; Scanlon, T. J.; John, B.; Emerson, D. R.; Brown, R. E.

    2016-11-01

    Hypersonic hybrid hydrodynamic-molecular gas flow solvers are required to satisfy the two essential requirements of any high-speed reacting code, these being physical accuracy and computational efficiency. The James Weir Fluids Laboratory at the University of Strathclyde is currently developing an open-source hybrid code which will eventually reconcile the direct simulation Monte-Carlo method, making use of the OpenFOAM application called dsmcFoam, and the newly coded open-source two-temperature computational fluid dynamics solver named hy2Foam. In conjunction with employing the CVDV chemistry-vibration model in hy2Foam, novel use is made of the QK rates in a CFD solver. In this paper, further testing is performed, in particular with the CFD solver, to ensure its efficacy before considering more advanced test cases. The hy2Foam and dsmcFoam codes have shown to compare reasonably well, thus providing a useful basis for other codes to compare against.

  9. Deodorants: an experimental provocation study with cinnamic aldehyde.

    PubMed

    Bruze, Magnus; Johansen, J D; Andersen, K E; Frosch, P; Lepoittevin, J-P; Rastogi, S; Wakelin, S; White, I; Menné, T

    2003-02-01

    Axillary dermatitis is common and overrepresented in individuals with contact allergy to fragrances. Many individuals suspect their deodorants to be the incriminating products. Our aim was to investigate the significance of cinnamic aldehyde in deodorants for the development of axillary dermatitis when used by individuals with and without contact allergy to cinnamic aldehyde. Patch tests with deodorants and ethanol solutions with cinnamic aldehyde, and repeated open application tests with roll-on deodorants without and with cinnamic aldehyde at different concentrations, were performed in 37 patients with dermatitis, 20 without and 17 with contact allergy to cinnamic aldehyde. A repeated open application test with positive findings was noted only in patients hypersensitive to cinnamic aldehyde (P <.001) and only in the axilla to which the deodorants containing cinnamic aldehyde had been applied (P <.001). Deodorants containing cinnamic aldehyde in the concentration range 0.01% to 0.32%, used twice daily on healthy skin, can elicit axillary dermatitis within a few weeks.

  10. Fracture mechanics life analytical methods verification testing

    NASA Technical Reports Server (NTRS)

    Favenesi, J. A.; Clemons, T. G.; Riddell, W. T.; Ingraffea, A. R.; Wawrzynek, P. A.

    1994-01-01

    The objective was to evaluate NASCRAC (trademark) version 2.0, a second generation fracture analysis code, for verification and validity. NASCRAC was evaluated using a combination of comparisons to the literature, closed-form solutions, numerical analyses, and tests. Several limitations and minor errors were detected. Additionally, a number of major flaws were discovered. These major flaws were generally due to application of a specific method or theory, not due to programming logic. Results are presented for the following program capabilities: K versus a, J versus a, crack opening area, life calculation due to fatigue crack growth, tolerable crack size, proof test logic, tearing instability, creep crack growth, crack transitioning, crack retardation due to overloads, and elastic-plastic stress redistribution. It is concluded that the code is an acceptable fracture tool for K solutions of simplified geometries, for a limited number of J and crack opening area solutions, and for fatigue crack propagation with the Paris equation and constant amplitude loads when the Paris equation is applicable.

  11. Stennis firefighters

    NASA Image and Video Library

    2012-05-11

    Instructor Rob Mortin watches as Stennis Space Center firefighters Lt. Greg Lampley, Rodney Boone, Vance Forrest and Billy Scarborough practice high-angle rope rescue techniques during a May 11, 2012, training exercise. The exercise specifically focused on scenarios applicable to the 300-foot-tall, open-steel-structure A-3 Test Stand under construction at the rocket engine test facility.

  12. Application of Component Scoring to a Complicated Cognitive Domain.

    ERIC Educational Resources Information Center

    Tatsuoka, Kikumi K.; Yamamoto, Kentaro

    This study used the Montague-Riley Test to introduce a new scoring procedure that revealed errors in cognitive processes occurring at subcomponents of an electricity problem. The test, consisting of four parts with 36 open-ended problems each, was administered to 250 high school students. A computer program, ELTEST, was written applying a…

  13. WriteSim TCExam - An open source text simulation environment for training novice researchers in scientific writing

    PubMed Central

    2010-01-01

    Background The ability to write clearly and effectively is of central importance to the scientific enterprise. Encouraged by the success of simulation environments in other biomedical sciences, we developed WriteSim TCExam, an open-source, Web-based, textual simulation environment for teaching effective writing techniques to novice researchers. We shortlisted and modified an existing open source application - TCExam to serve as a textual simulation environment. After testing usability internally in our team, we conducted formal field usability studies with novice researchers. These were followed by formal surveys with researchers fitting the role of administrators and users (novice researchers) Results The development process was guided by feedback from usability tests within our research team. Online surveys and formal studies, involving members of the Research on Research group and selected novice researchers, show that the application is user-friendly. Additionally it has been used to train 25 novice researchers in scientific writing to date and has generated encouraging results. Conclusion WriteSim TCExam is the first Web-based, open-source textual simulation environment designed to complement traditional scientific writing instruction. While initial reviews by students and educators have been positive, a formal study is needed to measure its benefits in comparison to standard instructional methods. PMID:20509946

  14. Specvis: Free and open-source software for visual field examination.

    PubMed

    Dzwiniel, Piotr; Gola, Mateusz; Wójcik-Gryciuk, Anna; Waleszczyk, Wioletta J

    2017-01-01

    Visual field impairment affects more than 100 million people globally. However, due to the lack of the access to appropriate ophthalmic healthcare in undeveloped regions as a result of associated costs and expertise this number may be an underestimate. Improved access to affordable diagnostic software designed for visual field examination could slow the progression of diseases, such as glaucoma, allowing for early diagnosis and intervention. We have developed Specvis, a free and open-source application written in Java programming language that can run on any personal computer to meet this requirement (http://www.specvis.pl/). Specvis was tested on glaucomatous, retinitis pigmentosa and stroke patients and the results were compared to results using the Medmont M700 Automated Static Perimeter. The application was also tested for inter-test intrapersonal variability. The results from both validation studies indicated low inter-test intrapersonal variability, and suitable reliability for a fast and simple assessment of visual field impairment. Specvis easily identifies visual field areas of zero sensitivity and allows for evaluation of its levels throughout the visual field. Thus, Specvis is a new, reliable application that can be successfully used for visual field examination and can fill the gap between confrontation and perimetry tests. The main advantages of Specvis over existing methods are its availability (free), affordability (runs on any personal computer), and reliability (comparable to high-cost solutions).

  15. Specvis: Free and open-source software for visual field examination

    PubMed Central

    Dzwiniel, Piotr; Gola, Mateusz; Wójcik-Gryciuk, Anna

    2017-01-01

    Visual field impairment affects more than 100 million people globally. However, due to the lack of the access to appropriate ophthalmic healthcare in undeveloped regions as a result of associated costs and expertise this number may be an underestimate. Improved access to affordable diagnostic software designed for visual field examination could slow the progression of diseases, such as glaucoma, allowing for early diagnosis and intervention. We have developed Specvis, a free and open-source application written in Java programming language that can run on any personal computer to meet this requirement (http://www.specvis.pl/). Specvis was tested on glaucomatous, retinitis pigmentosa and stroke patients and the results were compared to results using the Medmont M700 Automated Static Perimeter. The application was also tested for inter-test intrapersonal variability. The results from both validation studies indicated low inter-test intrapersonal variability, and suitable reliability for a fast and simple assessment of visual field impairment. Specvis easily identifies visual field areas of zero sensitivity and allows for evaluation of its levels throughout the visual field. Thus, Specvis is a new, reliable application that can be successfully used for visual field examination and can fill the gap between confrontation and perimetry tests. The main advantages of Specvis over existing methods are its availability (free), affordability (runs on any personal computer), and reliability (comparable to high-cost solutions). PMID:29028825

  16. [Investigation of a new highly porous hydroxyapatite matrix for obliterating open mastoid cavities - application in guinea pigs bulla].

    PubMed

    Punke, C; Zehlicke, T; Boltze, C; Pau, H W

    2009-04-01

    Many different techniques for obliterating open mastoid cavity have been described. The results after the application of alloplastic materials like Hydroxyapatite and Tricalciumphosphate were poor due to long-lasting resorption. Extrusion of those materials has been described. We investigated the applicability of a new high-porosity ceramic for obliterating large open mastoid cavities and tested it in an animal model (bulla of guinea pig). A highly porous matrix (NanoBone) bone-inductor fabricated in a sol-gel-technique was administered unilaterally into the opened bullae of 30 guinea pigs. In each animal the opposite bulla was filled with Bio-Oss, a bone substitute consisting of a portion of mineral bovine bone. Histological evaluations were performed 1, 2, 3, 4, 5 and 12 weeks after the implantation. After the initial phase with an inflammatory reaction creating a loose granulation tissue, we observed the formation of trabeculare bone within the fourth week in both groups. From the fifth week on we found osteoclasts on the surface of NanoBone and Bio-Oss with consecutive degradation of both materials. In our animal model study we found beneficial properties of the used bone-inductors NanoBone and Bio-Oss for obliterating open mastoid cavities.

  17. 76 FR 30341 - Town of Edgartown; Notice of Preliminary Permit Application Accepted for Filing and Soliciting...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-05-25

    ...), filed an application for a successive preliminary permit, pursuant to section 4(f) of the Federal Power Act (FPA), proposing to study the feasibility of the Muskeget Channel Tidal Energy Project to be..., and one experimental turbine unit that would be used to test various open- bladed and helical tidal...

  18. Evaluation of pollution prevention options to reduce styrene emissions from fiber-reinforced plastic open molding processes.

    PubMed

    Nunez, C M; Ramsey, G H; Kong, E J; Bahner, M A; Wright, R S; Clayton, C A; Baskir, J N

    1999-03-01

    Pollution prevention (P2) options to reduce styrene emissions, such as new materials and application equipment, are commercially available to the operators of open molding processes. However, information is lacking on the emissions reduction that these options can achieve. To meet this need, the U.S. Environmental Protection Agency's (EPA) Air Pollution Prevention and Control Division, working in collaboration with Research Triangle Institute, measured styrene emissions for several of these P2 options. In addition, the emission factors calculated from these test results were compared with the existing EPA emission factors for gel coat sprayup and resin applications. Results show that styrene emissions can be reduced by up to 52% by using controlled spraying (i.e., reducing overspray), low-styrene and styrene-suppressed materials, and nonatomizing application equipment. Also, calculated emission factors were 1.6-2.5 times greater than the mid-range EPA emission factors for the corresponding gel coat and resin application. These results indicate that facilities using existing EPA emission factors to estimate emissions in open molding processes are likely to underestimate actual emissions. Facilities should investigate the applicability and feasibility of these P2 options to reduce their styrene emissions.

  19. Digital time stamping system based on open source technologies.

    PubMed

    Miskinis, Rimantas; Smirnov, Dmitrij; Urba, Emilis; Burokas, Andrius; Malysko, Bogdan; Laud, Peeter; Zuliani, Francesco

    2010-03-01

    A digital time stamping system based on open source technologies (LINUX-UBUNTU, OpenTSA, OpenSSL, MySQL) is described in detail, including all important testing results. The system, called BALTICTIME, was developed under a project sponsored by the European Commission under the Program FP 6. It was designed to meet the requirements posed to the systems of legal and accountable time stamping and to be applicable to the hardware commonly used by the national time metrology laboratories. The BALTICTIME system is intended for the use of governmental and other institutions as well as personal bodies. Testing results demonstrate that the time stamps issued to the user by BALTICTIME and saved in BALTICTIME's archives (which implies that the time stamps are accountable) meet all the regulatory requirements. Moreover, the BALTICTIME in its present implementation is able to issue more than 10 digital time stamps per second. The system can be enhanced if needed. The test version of the BALTICTIME service is free and available at http://baltictime. pfi.lt:8080/btws/ and http://baltictime.lnmc.lv:8080/btws/.

  20. Support of Multidimensional Parallelism in the OpenMP Programming Model

    NASA Technical Reports Server (NTRS)

    Jin, Hao-Qiang; Jost, Gabriele

    2003-01-01

    OpenMP is the current standard for shared-memory programming. While providing ease of parallel programming, the OpenMP programming model also has limitations which often effect the scalability of applications. Examples for these limitations are work distribution and point-to-point synchronization among threads. We propose extensions to the OpenMP programming model which allow the user to easily distribute the work in multiple dimensions and synchronize the workflow among the threads. The proposed extensions include four new constructs and the associated runtime library. They do not require changes to the source code and can be implemented based on the existing OpenMP standard. We illustrate the concept in a prototype translator and test with benchmark codes and a cloud modeling code.

  1. A small, lightweight multipollutant sensor system for ground-mobile and aerial emission sampling from open area sources

    NASA Astrophysics Data System (ADS)

    Zhou, Xiaochi; Aurell, Johanna; Mitchell, William; Tabor, Dennis; Gullett, Brian

    2017-04-01

    Characterizing highly dynamic, transient, and vertically lofted emissions from open area sources poses unique measurement challenges. This study developed and applied a multipollutant sensor and time-integrated sampler system for use on mobile applications such as vehicles, tethered balloons (aerostats) and unmanned aerial vehicles (UAVs) to determine emission factors. The system is particularly applicable to open area sources, such as forest fires, due to its light weight (3.5 kg), compact size (6.75 L), and internal power supply. The sensor system, termed ;Kolibri;, consists of sensors measuring CO2 and CO, and samplers for particulate matter (PM) and volatile organic compounds (VOCs). The Kolibri is controlled by a microcontroller which can record and transfer data in real time through a radio module. Selection of the sensors was based on laboratory testing for accuracy, response delay and recovery, cross-sensitivity, and precision. The Kolibri was compared against rack-mounted continuous emissions monitoring system (CEMs) and another mobile sampling instrument (the ;Flyer;) that has been used in over ten open area pollutant sampling events. Our results showed that the time series of CO, CO2, and PM2.5 concentrations measured by the Kolibri agreed well with those from the CEMs and the Flyer, with a laboratory-tested percentage error of 4.9%, 3%, and 5.8%, respectively. The VOC emission factors obtained using the Kolibri were consistent with existing literature values that relate concentration to modified combustion efficiency. The potential effect of rotor downwash on particle sampling was investigated in an indoor laboratory and the preliminary results suggested that its influence is minimal. Field application of the Kolibri sampling open detonation plumes indicated that the CO and CO2 sensors responded dynamically and their concentrations co-varied with emission transients. The Kolibri system can be applied to various challenging open area scenarios such as fires, lagoons, flares, and landfills.

  2. Exploring the Role of Value Networks for Software Innovation

    NASA Astrophysics Data System (ADS)

    Morgan, Lorraine; Conboy, Kieran

    This paper describes a research-in-progress that aims to explore the applicability and implications of open innovation practices in two firms - one that employs agile development methods and another that utilizes open source software. The open innovation paradigm has a lot in common with open source and agile development methodologies. A particular strength of agile approaches is that they move away from 'introverted' development, involving only the development personnel, and intimately involves the customer in all areas of software creation, supposedly leading to the development of a more innovative and hence more valuable information system. Open source software (OSS) development also shares two key elements of the open innovation model, namely the collaborative development of the technology and shared rights to the use of the technology. However, one shortfall with agile development in particular is the narrow focus on a single customer representative. In response to this, we argue that current thinking regarding innovation needs to be extended to include multiple stakeholders both across and outside the organization. Additionally, for firms utilizing open source, it has been found that their position in a network of potential complementors determines the amount of superior value they create for their customers. Thus, this paper aims to get a better understanding of the applicability and implications of open innovation practices in firms that employ open source and agile development methodologies. In particular, a conceptual framework is derived for further testing.

  3. Enhancing Application Performance Using Mini-Apps: Comparison of Hybrid Parallel Programming Paradigms

    NASA Technical Reports Server (NTRS)

    Lawson, Gary; Poteat, Michael; Sosonkina, Masha; Baurle, Robert; Hammond, Dana

    2016-01-01

    In this work, several mini-apps have been created to enhance a real-world application performance, namely the VULCAN code for complex flow analysis developed at the NASA Langley Research Center. These mini-apps explore hybrid parallel programming paradigms with Message Passing Interface (MPI) for distributed memory access and either Shared MPI (SMPI) or OpenMP for shared memory accesses. Performance testing shows that MPI+SMPI yields the best execution performance, while requiring the largest number of code changes. A maximum speedup of 23X was measured for MPI+SMPI, but only 10X was measured for MPI+OpenMP.

  4. Clinical applications of correlational vestibular autorotation test.

    PubMed

    Hsieh, Li-Chun; Lin, Te-Ming; Chang, Yu-Min; Kuo, Terry B J; Lee, Gho-She

    2015-06-01

    The correlational vestibular autorotation test (VAT) system has the advantages of good test-retest reliability and calibrations of absolute degrees of eye movement are unnecessary when acquiring a cross correlation coefficient (CCC). The approach is able to efficiently detect peripheral vestibulopathies. A VAT has some drawbacks including poor test-retest reliability and slippage of sensor. This study aimed to develop a correlational VAT system and to evaluate the reliability and applicability of this system. Twenty healthy participants and 10 vertiginous patients were enrolled. Vertical and horizontal autorotations from 0 to 3 Hz with either closed or open eyes were performed. A small sensor and a wireless transmission technique were used to acquire the electro-ocular graph and head velocity signals. The two signals were analyzed using CCCs to assess the functioning of the vestibular ocular reflex (VOR). The results showed a significantly greater CCC for open-eye versus closed-eye of head autorotations. The CCCs also increased significantly with head rotational frequencies. Moreover, the CCCs significantly correlated with the VOR gains at autorotation frequencies ≥1.0 Hz. The test-retest reliability was good (intraclass correlation coefficients ≥0.85). The vertiginous participants had significantly lower individual CCCs and overall average CCC than age- and-gender matched controls.

  5. Increasing Flight Software Reuse with OpenSatKit

    NASA Technical Reports Server (NTRS)

    McComas, David C.

    2018-01-01

    In January 2015 the NASA Goddard Space Flight Center (GSFC) released the Core Flight System (cFS) as open source under the NASA Open Source Agreement (NOSA) license. The cFS is based on flight software (FSW) developed for 12 spacecraft spanning nearly two decades of effort and it can provide about a third of the FSW functionality for a low-earth orbiting scientific spacecraft. The cFS is a FSW framework that is portable, configurable, and extendable using a product line deployment model. However, the components are maintained separately so the user must configure, integrate, and deploy them as a cohesive functional system. This can be very challenging especially for organizations such as universities building cubesats that have minimal experience developing FSW. Supporting universities was one of the primary motivators for releasing the cFS under NOSA. This paper describes the OpenSatKit that was developed to address the cFS deployment challenges and to serve as a cFS training platform for new users. It provides a fully functional out-of-the box software system that includes NASA's cFS, Ball Aerospace's command and control system COSMOS, and a NASA dynamic simulator called 42. The kit is freely available since all of the components have been released as open source. The kit runs on a Linux platform, includes 8 cFS applications, several kit-specific applications, and built in demos illustrating how to use key application features. It also includes the software necessary to port the cFS to a Raspberry Pi and instructions for configuring COSMOS to communicate with the target. All of the demos and test scripts can be rerun unchanged with the cFS running on the Raspberry Pi. The cFS uses a 3-tiered layered architecture including a platform abstraction layer, a Core Flight Executive (cFE) middle layer, and an application layer. Similar to smart phones, the cFS application layer is the key architectural feature for users to extend the FSW functionality to meet their mission-specific requirements. The platform abstraction layer and the cFE layers go a step further than smart phones by providing a platform-agnostic Application Programmer Interface (API) that allows applications to run unchanged on different platforms. OpenSatKit can serve two significant architectural roles that will further help the adoption of the cFS and help create a community of users that can share assets. First, the kit is being enhanced to automate the integration of applications with the goal of creating a virtual cFS "App Store".. Second, a platform certification test suite can be developed that would allow users to verify the port of the cFS to a new platform. This paper will describe the current state of these efforts and future plans.

  6. MicMac GIS application: free open source

    NASA Astrophysics Data System (ADS)

    Duarte, L.; Moutinho, O.; Teodoro, A.

    2016-10-01

    The use of Remotely Piloted Aerial System (RPAS) for remote sensing applications is becoming more frequent as the technologies on on-board cameras and the platform itself are becoming a serious contender to satellite and airplane imagery. MicMac is a photogrammetric tool for image matching that can be used in different contexts. It is an open source software and it can be used as a command line or with a graphic interface (for each command). The main objective of this work was the integration of MicMac with QGIS, which is also an open source software, in order to create a new open source tool applied to photogrammetry/remote sensing. Python language was used to develop the application. This tool would be very useful in the manipulation and 3D modelling of a set of images. The main objective was to create a toolbar in QGIS with the basic functionalities with intuitive graphic interfaces. The toolbar is composed by three buttons: produce the points cloud, create the Digital Elevation Model (DEM) and produce the orthophoto of the study area. The application was tested considering 35 photos, a subset of images acquired by a RPAS in the Aguda beach area, Porto, Portugal. They were used in order to create a 3D terrain model and from this model obtain an orthophoto and the corresponding DEM. The code is open and can be modified according to the user requirements. This integration would be very useful in photogrammetry and remote sensing community combined with GIS capabilities.

  7. Using a web-based application to define the accuracy of diagnostic tests when the gold standard is imperfect.

    PubMed

    Lim, Cherry; Wannapinij, Prapass; White, Lisa; Day, Nicholas P J; Cooper, Ben S; Peacock, Sharon J; Limmathurotsakul, Direk

    2013-01-01

    Estimates of the sensitivity and specificity for new diagnostic tests based on evaluation against a known gold standard are imprecise when the accuracy of the gold standard is imperfect. Bayesian latent class models (LCMs) can be helpful under these circumstances, but the necessary analysis requires expertise in computational programming. Here, we describe open-access web-based applications that allow non-experts to apply Bayesian LCMs to their own data sets via a user-friendly interface. Applications for Bayesian LCMs were constructed on a web server using R and WinBUGS programs. The models provided (http://mice.tropmedres.ac) include two Bayesian LCMs: the two-tests in two-population model (Hui and Walter model) and the three-tests in one-population model (Walter and Irwig model). Both models are available with simplified and advanced interfaces. In the former, all settings for Bayesian statistics are fixed as defaults. Users input their data set into a table provided on the webpage. Disease prevalence and accuracy of diagnostic tests are then estimated using the Bayesian LCM, and provided on the web page within a few minutes. With the advanced interfaces, experienced researchers can modify all settings in the models as needed. These settings include correlation among diagnostic test results and prior distributions for all unknown parameters. The web pages provide worked examples with both models using the original data sets presented by Hui and Walter in 1980, and by Walter and Irwig in 1988. We also illustrate the utility of the advanced interface using the Walter and Irwig model on a data set from a recent melioidosis study. The results obtained from the web-based applications were comparable to those published previously. The newly developed web-based applications are open-access and provide an important new resource for researchers worldwide to evaluate new diagnostic tests.

  8. Definition of mutually optimum NDI and proof test criteria for 2219 aluminum pressure vessels. Volume 1: Methods

    NASA Technical Reports Server (NTRS)

    Schwartzberg, F. R.; King, R. G.; Todd, P. H., Jr.

    1979-01-01

    The requirements for proof testing and nondestructive inspection of aluminum pressure vessels were discussed. The following conclusions are (1) lack-of-fusion weld defects are sufficiently tight in the as-welded condition to be considered undetectable; (2) proof-level loads are required to fully open lack-of-fusion weld defects; (3) significant crack opening occurs at subproof levels so that an inspection enhancement loading treatment designed to avoid catastrophic failure is feasible; (4) currently used proof levels for 2219 pressure vessels are adequate for postproof inspection; (5) quantification of defect size and location using collimated ultrasonic pitch-catch techniques appears sufficiently feasible for tankage to warrant developmental work; (6) for short-time single-cycle pressure-vessel applications, postproof inspection is desirable; and (7) for long-term multiple-cycle pressure-vessel applications, postproof inspection is essential for life assurance.

  9. dsmcFoam+: An OpenFOAM based direct simulation Monte Carlo solver

    NASA Astrophysics Data System (ADS)

    White, C.; Borg, M. K.; Scanlon, T. J.; Longshaw, S. M.; John, B.; Emerson, D. R.; Reese, J. M.

    2018-03-01

    dsmcFoam+ is a direct simulation Monte Carlo (DSMC) solver for rarefied gas dynamics, implemented within the OpenFOAM software framework, and parallelised with MPI. It is open-source and released under the GNU General Public License in a publicly available software repository that includes detailed documentation and tutorial DSMC gas flow cases. This release of the code includes many features not found in standard dsmcFoam, such as molecular vibrational and electronic energy modes, chemical reactions, and subsonic pressure boundary conditions. Since dsmcFoam+ is designed entirely within OpenFOAM's C++ object-oriented framework, it benefits from a number of key features: the code emphasises extensibility and flexibility so it is aimed first and foremost as a research tool for DSMC, allowing new models and test cases to be developed and tested rapidly. All DSMC cases are as straightforward as setting up any standard OpenFOAM case, as dsmcFoam+ relies upon the standard OpenFOAM dictionary based directory structure. This ensures that useful pre- and post-processing capabilities provided by OpenFOAM remain available even though the fully Lagrangian nature of a DSMC simulation is not typical of most OpenFOAM applications. We show that dsmcFoam+ compares well to other well-known DSMC codes and to analytical solutions in terms of benchmark results.

  10. Testing the role of patch openness as a causal mechanism for apparent area sensitivity in a grassland specialist.

    PubMed

    Keyel, Alexander C; Bauer, Carolyn M; Lattin, Christine R; Romero, L Michael; Reed, J Michael

    2012-06-01

    Area sensitivity, species being disproportionately present on larger habitat patches, has been identified in many taxa. We propose that some apparently area-sensitive species are actually responding to how open a habitat patch is, rather than to patch size. We tested this hypothesis for Bobolinks (Dolichonyx oryzivorus) by comparing density and occupancy to a novel openness index, patch area, and edge effects. Bobolink density and occupancy showed significant relationships with openness, but logistic models based on an openness occupancy threshold had greater explanatory power. Thresholds remained approximately consistent from June through August, and shifted to be more open in September. Variance partitioning supported the openness index as unique and relevant. We found no relationships between measures of body condition (body mass, body size, circulating corticosterone levels) and either openness or area. Our findings have implications for studies of area sensitivity, especially with regards to inconsistencies reported within species: specifically, (1) whether or not a study finds a species to be area sensitive may depend on whether small, open sites were sampled, and (2) area regressions were sensitive to observed densities at the largest sites, suggesting that variation in these fields could lead to inconsistent area sensitivity responses. Responses to openness may be a consequence of habitat selection mediated by predator effects. Finally, openness measures may have applications for predicting effects of habitat management or development, such as adding wind turbines, in open habitat.

  11. Mechanical and analytical screening of braided composites for transport fuselage applications

    NASA Technical Reports Server (NTRS)

    Fedro, Mark J.; Gunther, Christian; Ko, Frank K.

    1991-01-01

    The mechanics of materials progress in support of the goal of understanding the application of braided composites in a transport aircraft fuselage are summarized. Composites consisting of both 2-D and 3-D braid patterns are investigated. Both consolidation of commingled graphite/PEEK and resin transfer molding of graphite-epoxy braided composite processes are studied. Mechanical tests were used to examine unnotched tension, open hole tension, compression, compression after impact, in-plane shear, out-of-plane tension, bearing, and crippling. Analytical methods are also developed and applied to predict the stiffness and strengths of test specimens. A preliminary study using the test data and analytical results is performed to assess the applicability of braided composites to a commercial aircraft fuselage.

  12. Colleges Making SAT Optional as Admissions Requirement

    ERIC Educational Resources Information Center

    Gilroy, Marilyn

    2007-01-01

    This article reports that more colleges are dropping the SAT as a requirement for admission and, in many cases, these institutions are attracting a larger and more diverse pool of applicants. According to the National Center for Fair & Open Testing (FairTest), 740 schools have made the SATs optional. The list includes some of the nation's most…

  13. Hybrid MPI+OpenMP Programming of an Overset CFD Solver and Performance Investigations

    NASA Technical Reports Server (NTRS)

    Djomehri, M. Jahed; Jin, Haoqiang H.; Biegel, Bryan (Technical Monitor)

    2002-01-01

    This report describes a two level parallelization of a Computational Fluid Dynamic (CFD) solver with multi-zone overset structured grids. The approach is based on a hybrid MPI+OpenMP programming model suitable for shared memory and clusters of shared memory machines. The performance investigations of the hybrid application on an SGI Origin2000 (O2K) machine is reported using medium and large scale test problems.

  14. The results of the investigations of Russian Research Center - {open_quotes}Kurchatov Institute{close_quotes} on molten salt applications to problems of nuclear energy systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Novikov, V.M.

    1995-10-01

    The results of investigations on molten salt (MS) applications to problems of nuclear energy systems that have been conducted in Russian Research {open_quotes}Kurchatov Institute{close_quotes} are presented and discussed. The spectrum of these investigations is rather broad and covers the following items: physical characteristics of molten salt nuclear energy systems (MSNES); nuclear and radiation safety of MSNES; construction materials compatible with MS of different compositions; technological aspects of MS loops; in-reactor loop testing. It is shown that main findings of completed program support the conclusion that there are no physical nor technological obstacles on way of MS application to different nuclearmore » energy systems.« less

  15. Similarity Metrics for Closed Loop Dynamic Systems

    NASA Technical Reports Server (NTRS)

    Whorton, Mark S.; Yang, Lee C.; Bedrossian, Naz; Hall, Robert A.

    2008-01-01

    To what extent and in what ways can two closed-loop dynamic systems be said to be "similar?" This question arises in a wide range of dynamic systems modeling and control system design applications. For example, bounds on error models are fundamental to the controller optimization with modern control design methods. Metrics such as the structured singular value are direct measures of the degree to which properties such as stability or performance are maintained in the presence of specified uncertainties or variations in the plant model. Similarly, controls-related areas such as system identification, model reduction, and experimental model validation employ measures of similarity between multiple realizations of a dynamic system. Each area has its tools and approaches, with each tool more or less suited for one application or the other. Similarity in the context of closed-loop model validation via flight test is subtly different from error measures in the typical controls oriented application. Whereas similarity in a robust control context relates to plant variation and the attendant affect on stability and performance, in this context similarity metrics are sought that assess the relevance of a dynamic system test for the purpose of validating the stability and performance of a "similar" dynamic system. Similarity in the context of system identification is much more relevant than are robust control analogies in that errors between one dynamic system (the test article) and another (the nominal "design" model) are sought for the purpose of bounding the validity of a model for control design and analysis. Yet system identification typically involves open-loop plant models which are independent of the control system (with the exception of limited developments in closed-loop system identification which is nonetheless focused on obtaining open-loop plant models from closed-loop data). Moreover the objectives of system identification are not the same as a flight test and hence system identification error metrics are not directly relevant. In applications such as launch vehicles where the open loop plant is unstable it is similarity of the closed-loop system dynamics of a flight test that are relevant.

  16. A generalized Kruskal-Wallis test incorporating group uncertainty with application to genetic association studies.

    PubMed

    Acar, Elif F; Sun, Lei

    2013-06-01

    Motivated by genetic association studies of SNPs with genotype uncertainty, we propose a generalization of the Kruskal-Wallis test that incorporates group uncertainty when comparing k samples. The extended test statistic is based on probability-weighted rank-sums and follows an asymptotic chi-square distribution with k - 1 degrees of freedom under the null hypothesis. Simulation studies confirm the validity and robustness of the proposed test in finite samples. Application to a genome-wide association study of type 1 diabetic complications further demonstrates the utilities of this generalized Kruskal-Wallis test for studies with group uncertainty. The method has been implemented as an open-resource R program, GKW. © 2013, The International Biometric Society.

  17. Limulus amoebocyte lysate test via an open-microcavity optical biosensor

    NASA Astrophysics Data System (ADS)

    Scudder, Jonathan; Ye, Jing Yong

    2018-02-01

    Almost since its discovery, Limulus amoebocyte lysate (LAL) testing has been an important part of the pharmaceutical quality control toolkit. It allows for in vitro endotoxin testing, which has replaced tests using animals, such as using rabbits' thermal response to judge pyrogenicity of test samples, thus leading to a less expensive and faster test of parenteral pharmaceuticals and medical devices that contact blood or cerebrospinal fluid. However, limited by the detection mechanisms of the LAL assays currently used in industry, further improvement in their performance is challenging. To address the growing demand on optimizing LAL assays for increased test sensitivity and reduced assay time, we have developed an LAL assay approach based on a detection mechanism that is different from those being used in industry, namely, gel-clot, turbidimetric, and chromogenic detection. Using a unique open-microcavity photonic-crystal biosensor to monitor the change in the refractive index due to the reaction between LAL regents and endotoxins, we have demonstrated that this approach has improved the LAL assay sensitivity by 200 times compared with the commercial standard methods, reduced the time needed for the assay by more than half, and eliminated the necessity to incubate the test samples. This study opens up the possibility of using the significantly improved LAL assays for a wide range of applications.

  18. Model-Based Reinforcement of Kinect Depth Data for Human Motion Capture Applications

    PubMed Central

    Calderita, Luis Vicente; Bandera, Juan Pedro; Bustos, Pablo; Skiadopoulos, Andreas

    2013-01-01

    Motion capture systems have recently experienced a strong evolution. New cheap depth sensors and open source frameworks, such as OpenNI, allow for perceiving human motion on-line without using invasive systems. However, these proposals do not evaluate the validity of the obtained poses. This paper addresses this issue using a model-based pose generator to complement the OpenNI human tracker. The proposed system enforces kinematics constraints, eliminates odd poses and filters sensor noise, while learning the real dimensions of the performer's body. The system is composed by a PrimeSense sensor, an OpenNI tracker and a kinematics-based filter and has been extensively tested. Experiments show that the proposed system improves pure OpenNI results at a very low computational cost. PMID:23845933

  19. Swan: A tool for porting CUDA programs to OpenCL

    NASA Astrophysics Data System (ADS)

    Harvey, M. J.; De Fabritiis, G.

    2011-04-01

    The use of modern, high-performance graphical processing units (GPUs) for acceleration of scientific computation has been widely reported. The majority of this work has used the CUDA programming model supported exclusively by GPUs manufactured by NVIDIA. An industry standardisation effort has recently produced the OpenCL specification for GPU programming. This offers the benefits of hardware-independence and reduced dependence on proprietary tool-chains. Here we describe a source-to-source translation tool, "Swan" for facilitating the conversion of an existing CUDA code to use the OpenCL model, as a means to aid programmers experienced with CUDA in evaluating OpenCL and alternative hardware. While the performance of equivalent OpenCL and CUDA code on fixed hardware should be comparable, we find that a real-world CUDA application ported to OpenCL exhibits an overall 50% increase in runtime, a reduction in performance attributable to the immaturity of contemporary compilers. The ported application is shown to have platform independence, running on both NVIDIA and AMD GPUs without modification. We conclude that OpenCL is a viable platform for developing portable GPU applications but that the more mature CUDA tools continue to provide best performance. Program summaryProgram title: Swan Catalogue identifier: AEIH_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEIH_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU Public License version 2 No. of lines in distributed program, including test data, etc.: 17 736 No. of bytes in distributed program, including test data, etc.: 131 177 Distribution format: tar.gz Programming language: C Computer: PC Operating system: Linux RAM: 256 Mbytes Classification: 6.5 External routines: NVIDIA CUDA, OpenCL Nature of problem: Graphical Processing Units (GPUs) from NVIDIA are preferentially programed with the proprietary CUDA programming toolkit. An alternative programming model promoted as an industry standard, OpenCL, provides similar capabilities to CUDA and is also supported on non-NVIDIA hardware (including multicore ×86 CPUs, AMD GPUs and IBM Cell processors). The adaptation of a program from CUDA to OpenCL is relatively straightforward but laborious. The Swan tool facilitates this conversion. Solution method:Swan performs a translation of CUDA kernel source code into an OpenCL equivalent. It also generates the C source code for entry point functions, simplifying kernel invocation from the host program. A concise host-side API abstracts the CUDA and OpenCL APIs. A program adapted to use Swan has no dependency on the CUDA compiler for the host-side program. The converted program may be built for either CUDA or OpenCL, with the selection made at compile time. Restrictions: No support for CUDA C++ features Running time: Nominal

  20. Subscale Validation of the Subsurface Active Filtration of Exhaust (SAFE) Approach to NTP Ground Testing

    NASA Technical Reports Server (NTRS)

    Marshall, William M.; Borowski, Stanley K.; Bulman, Mel; Joyner, Russell; Martin, Charles R.

    2015-01-01

    Brief History of NTP: Project Rover Began in 1950s by Los Alamos Scientific Labs (now Los Alamos National Labs) and ran until 1970s Tested a series of nuclear reactor engines of varying size at Nevada Test Site (now Nevada National Security Site) Ranged in scale from 111 kN (25 klbf) to 1.1 MN (250 klbf) Included Nuclear Furnace-1 tests Demonstrated the viability and capability of a nuclear rocket engine test program One of Kennedys 4 goals during famous moon speech to Congress Nuclear Engines for Rocket Vehicle Applications (NERVA) Atomic Energy Commission and NASA joint venture started in 1964 Parallel effort to Project Rover was focused on technology demonstration Tested XE engine, a 245-kN (55-klbf) engine to demonstrate startup shutdown sequencing. Hot-hydrogen stream is passed directly through fuel elements potential for radioactive material to be eroded into gaseous fuel flow as identified in previous programs NERVA and Project Rover (1950s-70s) were able to test in open atmosphere similar to conventional rocket engine test stands today Nuclear Furance-1 tests employed a full scrubber system Increased government and environmental regulations prohibit the modern testing in open atmosphere. Since the 1960s, there has been an increasing cessation on open air testing of nuclear material Political and national security concerns further compound the regulatory environment

  1. Clinical Utilization of Repeated Open Application Test Among American Contact Dermatitis Society Members.

    PubMed

    Brown, Gabrielle E; Botto, Nina; Butler, Daniel C; Murase, Jenny E

    2015-01-01

    The repeated open application test (ROAT) provides useful information regarding allergens in suspected cases of allergic contact dermatitis; however, standardized methodology has not been established. The aim of this study was to assess how ROAT is used in clinical and research settings. We distributed a survey regarding ROAT practice to the American Contact Dermatitis Society and conducted a literature review of ROAT utilization in research. A total of 67 American Contact Dermatitis Society members participated in the survey. Respondents most frequently recommend application of leave-on products twice daily (46.0%) and rinse-off products once daily (43.5%). The most commonly used anatomical sites include the forearm (38.7%) and antecubital fossa (32.3%). Most respondents continue ROAT for 1 (49.2%) or 2 weeks (31.7%). Literature review of 32 studies (26 leave-on, 6 rinse-off) revealed that application frequency is most common at twice daily for both leave-on (96.2%) and rinse-off (50.0%) products. The most common anatomical site is the forearm (62.5%), with an overall study duration of 3 to 4 weeks (65.6%). When comparing ROAT clinical and research practice, the majority trend was consistent for leave-on product application frequency and anatomical site, but not for rinse-off product application frequency, or overall duration. Further research is needed to determine best practice recommendations.

  2. Exploring Infiniband Hardware Virtualization in OpenNebula towards Efficient High-Performance Computing

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pais Pitta de Lacerda Ruivo, Tiago; Bernabeu Altayo, Gerard; Garzoglio, Gabriele

    2014-11-11

    has been widely accepted that software virtualization has a big negative impact on high-performance computing (HPC) application performance. This work explores the potential use of Infiniband hardware virtualization in an OpenNebula cloud towards the efficient support of MPI-based workloads. We have implemented, deployed, and tested an Infiniband network on the FermiCloud private Infrastructure-as-a-Service (IaaS) cloud. To avoid software virtualization towards minimizing the virtualization overhead, we employed a technique called Single Root Input/Output Virtualization (SRIOV). Our solution spanned modifications to the Linux’s Hypervisor as well as the OpenNebula manager. We evaluated the performance of the hardware virtualization on up to 56more » virtual machines connected by up to 8 DDR Infiniband network links, with micro-benchmarks (latency and bandwidth) as well as w a MPI-intensive application (the HPL Linpack benchmark).« less

  3. Infrastructure for Multiphysics Software Integration in High Performance Computing-Aided Science and Engineering

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Campbell, Michael T.; Safdari, Masoud; Kress, Jessica E.

    The project described in this report constructed and exercised an innovative multiphysics coupling toolkit called the Illinois Rocstar MultiPhysics Application Coupling Toolkit (IMPACT). IMPACT is an open source, flexible, natively parallel infrastructure for coupling multiple uniphysics simulation codes into multiphysics computational systems. IMPACT works with codes written in several high-performance-computing (HPC) programming languages, and is designed from the beginning for HPC multiphysics code development. It is designed to be minimally invasive to the individual physics codes being integrated, and has few requirements on those physics codes for integration. The goal of IMPACT is to provide the support needed to enablemore » coupling existing tools together in unique and innovative ways to produce powerful new multiphysics technologies without extensive modification and rewrite of the physics packages being integrated. There are three major outcomes from this project: 1) construction, testing, application, and open-source release of the IMPACT infrastructure, 2) production of example open-source multiphysics tools using IMPACT, and 3) identification and engagement of interested organizations in the tools and applications resulting from the project. This last outcome represents the incipient development of a user community and application echosystem being built using IMPACT. Multiphysics coupling standardization can only come from organizations working together to define needs and processes that span the space of necessary multiphysics outcomes, which Illinois Rocstar plans to continue driving toward. The IMPACT system, including source code, documentation, and test problems are all now available through the public gitHUB.org system to anyone interested in multiphysics code coupling. Many of the basic documents explaining use and architecture of IMPACT are also attached as appendices to this document. Online HTML documentation is available through the gitHUB site. There are over 100 unit tests provided that run through the Illinois Rocstar Application Development (IRAD) lightweight testing infrastructure that is also supplied along with IMPACT. The package as a whole provides an excellent base for developing high-quality multiphysics applications using modern software development practices. To facilitate understanding how to utilize IMPACT effectively, two multiphysics systems have been developed and are available open-source through gitHUB. The simpler of the two systems, named ElmerFoamFSI in the repository, is a multiphysics, fluid-structure-interaction (FSI) coupling of the solid mechanics package Elmer with a fluid dynamics module from OpenFOAM. This coupling illustrates how to combine software packages that are unrelated by either author or architecture and combine them into a robust, parallel multiphysics system. A more complex multiphysics tool is the Illinois Rocstar Rocstar Multiphysics code that was rebuilt during the project around IMPACT. Rocstar Multiphysics was already an HPC multiphysics tool, but now that it has been rearchitected around IMPACT, it can be readily expanded to capture new and different physics in the future. In fact, during this project, the Elmer and OpenFOAM tools were also coupled into Rocstar Multiphysics and demonstrated. The full Rocstar Multiphysics codebase is also available on gitHUB, and licensed for any organization to use as they wish. Finally, the new IMPACT product is already being used in several multiphysics code coupling projects for the Air Force, NASA and the Missile Defense Agency, and initial work on expansion of the IMPACT-enabled Rocstar Multiphysics has begun in support of a commercial company. These initiatives promise to expand the interest and reach of IMPACT and Rocstar Multiphysics, ultimately leading to the envisioned standardization and consortium of users that was one of the goals of this project.« less

  4. Friction Angles of Open-Graded Aggregates from Large-Scale Direct Shear Testing : TechBrief

    DOT National Transportation Integrated Search

    2013-07-08

    State and local transportation agencies frequently use opengraded aggregates for wall, roadway, and bridge construction. The primary advantages of using this type of material in wall and abutment applications are ease of constructability, lighter in-...

  5. Enhancing Application Performance Using Mini-Apps: Comparison of Hybrid Parallel Programming Paradigms

    NASA Technical Reports Server (NTRS)

    Lawson, Gary; Sosonkina, Masha; Baurle, Robert; Hammond, Dana

    2017-01-01

    In many fields, real-world applications for High Performance Computing have already been developed. For these applications to stay up-to-date, new parallel strategies must be explored to yield the best performance; however, restructuring or modifying a real-world application may be daunting depending on the size of the code. In this case, a mini-app may be employed to quickly explore such options without modifying the entire code. In this work, several mini-apps have been created to enhance a real-world application performance, namely the VULCAN code for complex flow analysis developed at the NASA Langley Research Center. These mini-apps explore hybrid parallel programming paradigms with Message Passing Interface (MPI) for distributed memory access and either Shared MPI (SMPI) or OpenMP for shared memory accesses. Performance testing shows that MPI+SMPI yields the best execution performance, while requiring the largest number of code changes. A maximum speedup of 23 was measured for MPI+SMPI, but only 11 was measured for MPI+OpenMP.

  6. Culture-independent diagnostic testing: have we opened Pandora's box for good?

    PubMed

    Janda, J Michael; Abbott, Sharon A

    2014-11-01

    The ability to accurately and quickly identify microbial agents associated with infectious diseases has been a longstanding and continuous goal of diagnostic microbiology laboratories. Over the course of several decades, technology and testing methodologies in this field have gradually evolved from traditional- or classic-based culture and identification approaches to antigen capture systems and more molecular-oriented applications. Recently, these molecular-based applications have signaled a new era in clinical diagnostic microbiology with the commercial introduction of culture-independent diagnostic testing (CIDT) systems. The first major commercial venture into the CIDT arena involves the detection of acute bacterial gastroenteritis. Several commercial products are now on the market globally with at least 4 Food and Drug Administration approved since January of 2013. These new systems offer the direct detection of a variety of enteropathogens quickly without the need for traditional culture. In Greek mythology, Pandora opened a "jar" or "box" out of curiosity thereby releasing all of humanity's evils most notably diseases and plagues according to Hesiod's Theogony. While not ill-intentioned the only thing left in the box was Hope. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Quantitative patch and repeated open application testing in hydroxyisohexyl 3-cyclohexene carboxaldehyde sensitive-patients.

    PubMed

    Schnuch, Axel; Uter, Wolfgang; Dickel, Heinrich; Szliska, Christiane; Schliemann, Sibylle; Eben, Ricarda; Ruëff, Franziska; Gimenez-Arnau, Ana; Löffler, Harald; Aberer, Werner; Frambach, Yvonne; Worm, Margitta; Niebuhr, Margarete; Hillen, Uwe; Martin, Vera; Jappe, Uta; Frosch, Peter J; Mahler, Vera

    2009-09-01

    To identify the concentration of the fragrance compound hydroxyisohexyl 3-cyclohexene carboxaldehyde (INCI) (HICC) that is sufficiently low not to cause an allergic reaction in patients with proven sensitization. Repeated open application testing (ROAT) in 64 subjects with 2 preparations (perfume and cream) in different concentration (0.005-2.5%). Confirmatory patch testing with four preparations in two different concentrations (2.5% and 5%). The concentrations of HICC being tolerated by 90% of those sensitized to HICC are estimated as <88.2 ppm (cream) and <270 ppm (perfume) equivalent to 1.2 microg/cm(2) (perfume) and 4.9 microg/cm(2) (cream). Patch test preparations differed with regard to sensitivity (88.5-98.1%) and specificity (37.5-87.5%) against the ROAT result as external criterion. ROAT concentrations and the reaction strength in patch testing were inversely correlated (Kendall's tau-b: 0.69), both indicating the existence of different degrees of susceptibility. To protect 90% (50%) of people sensitized, the use concentration should be in the range of 0.009-0.027% (0.18-0.34%), depending on the product type. Taking into account these results, excessive concentrations should be avoided, as this would continue to sensitize people. Close monitoring is indispensable to prove the efficacy of any recommendations aiming to prevent induction.

  8. Increasing Flight Software Reuse with OpenSatKit

    NASA Technical Reports Server (NTRS)

    McComas, David

    2018-01-01

    In January 2015 the NASA Goddard Space Flight Center (GSFC) released the Core Flight System (cFS) as open source under the NASA Open Source Agreement (NOSA) license. The cFS is based on flight software (FSW) developed for 12 spacecraft spanning nearly two decades of effort and it can provide about a third of the FSW functionality for a low-earth orbiting scientific spacecraft. The cFS is a FSW framework that is portable, configurable, and extendable using a product line deployment model. However, the components are maintained separately so the user must configure, integrate, and deploy them as a cohesive functional system. This can be very challenging especially for organizations such as universities building cubesats that have minimal experience developing FSW. Supporting universities was one of the primary motivators for releasing the cFS under NOSA. This paper describes the OpenSatKit that was developed to address the cFS deployment challenges and to serve as a cFS training platform for new users. It provides a fully functional out-of-the box software system that includes NASA's cFS, Ball Aerospaceâ€"TM"s command and control system COSMOS, and a NASA dynamic simulator called 42. The kit is freely available since all of the components have been released as open source. The kit runs on a Linux platform, includes 8 cFS applications, several kit-specific applications, and built in demos illustrating how to use key application features. It also includes the software necessary to port the cFS to a Raspberry Pi and instructions for configuring COSMOS to communicate with the target. All of the demos and test scripts can be rerun unchanged with the cFS running on the Raspberry Pi. The cFS uses a 3-tiered layered architecture including a platform abstraction layer, a Core Flight Executive (cFE) middle layer, and an application layer. Similar to smart phones, the cFS application layer is the key architectural feature for userâ€"TM"s to extend the FSW functionality to meet their mission-specific requirements. The platform abstraction layer and the cFE layers go a step further than smart phones by providing a platform-agnostic Application Programmer Interface (API) that allows applications to run unchanged on different platforms. OpenSatKit can serve two significant architectural roles that will further help the adoption of the cFS and help create a community of users that can share assets. First, the kit is being enhanced to automate the integration of applications with the goal of creating a virtual cFS 'App Store'. Second, a platform certification test suite can be developed that would allow users to verify the port of the cFS to a new platform. This paper will describe the current state of these efforts and future plans.

  9. Dropout rates in medical students at one school before and after the installation of admission tests in Austria.

    PubMed

    Reibnegger, Gilbert; Caluba, Hans-Christian; Ithaler, Daniel; Manhal, Simone; Neges, Heide Maria; Smolle, Josef

    2011-08-01

    Admission to medical studies in Austria since academic year 2005-2006 has been regulated by admission tests. At the Medical University of Graz, an admission test focusing on secondary-school-level knowledge in natural sciences has been used for this purpose. The impact of this important change on dropout rates of female versus male students and older versus younger students is reported. All 2,860 students admitted to the human medicine diploma program at the Medical University of Graz from academic years 2002-2003 to 2008-2009 were included. Nonparametric and semiparametric survival analysis techniques were employed to compare cumulative probability of dropout between demographic groups. Cumulative probability of dropout was significantly reduced in students selected by active admission procedure versus those admitted openly (P < .0001). Relative hazard ratio of selected versus openly admitted students was only 0.145 (95% CI, 0.106-0.198). Among openly admitted students, but not for selected ones, the cumulative probabilities for dropout were higher for females (P < .0001) and for older students (P < .0001). Generally, dropout hazard is highest during the second year of study. The introduction of admission testing significantly decreased the cumulative probability for dropout. In openly admitted students a significantly higher risk for dropout was found in female students and in older students, whereas no such effects can be detected after admission testing. Future research should focus on the sex dependence, with the aim of improving success rates among female applicants on the admission tests.

  10. An Extension to Deng's Entropy in the Open World Assumption with an Application in Sensor Data Fusion.

    PubMed

    Tang, Yongchuan; Zhou, Deyun; Chan, Felix T S

    2018-06-11

    Quantification of uncertain degree in the Dempster-Shafer evidence theory (DST) framework with belief entropy is still an open issue, even a blank field for the open world assumption. Currently, the existed uncertainty measures in the DST framework are limited to the closed world where the frame of discernment (FOD) is assumed to be complete. To address this issue, this paper focuses on extending a belief entropy to the open world by considering the uncertain information represented as the FOD and the nonzero mass function of the empty set simultaneously. An extension to Deng’s entropy in the open world assumption (EDEOW) is proposed as a generalization of the Deng’s entropy and it can be degenerated to the Deng entropy in the closed world wherever necessary. In order to test the reasonability and effectiveness of the extended belief entropy, an EDEOW-based information fusion approach is proposed and applied to sensor data fusion under uncertainty circumstance. The experimental results verify the usefulness and applicability of the extended measure as well as the modified sensor data fusion method. In addition, a few open issues still exist in the current work: the necessary properties for a belief entropy in the open world assumption, whether there exists a belief entropy that satisfies all the existed properties, and what is the most proper fusion frame for sensor data fusion under uncertainty.

  11. OSI: Will It Ever See the Light of Day?

    ERIC Educational Resources Information Center

    Moloney, Peter

    1997-01-01

    Examines issues of viability and necessity regarding the Open System Interconnections (OSI) reference service model with a view on future developments. Discusses problems with the standards; conformance testing; OSI bureaucracy; standardized communications; security; the transport level; applications; the stakeholders (communications providers,…

  12. Orchestrating high-throughput genomic analysis with Bioconductor

    PubMed Central

    Huber, Wolfgang; Carey, Vincent J.; Gentleman, Robert; Anders, Simon; Carlson, Marc; Carvalho, Benilton S.; Bravo, Hector Corrada; Davis, Sean; Gatto, Laurent; Girke, Thomas; Gottardo, Raphael; Hahne, Florian; Hansen, Kasper D.; Irizarry, Rafael A.; Lawrence, Michael; Love, Michael I.; MacDonald, James; Obenchain, Valerie; Oleś, Andrzej K.; Pagès, Hervé; Reyes, Alejandro; Shannon, Paul; Smyth, Gordon K.; Tenenbaum, Dan; Waldron, Levi; Morgan, Martin

    2015-01-01

    Bioconductor is an open-source, open-development software project for the analysis and comprehension of high-throughput data in genomics and molecular biology. The project aims to enable interdisciplinary research, collaboration and rapid development of scientific software. Based on the statistical programming language R, Bioconductor comprises 934 interoperable packages contributed by a large, diverse community of scientists. Packages cover a range of bioinformatic and statistical applications. They undergo formal initial review and continuous automated testing. We present an overview for prospective users and contributors. PMID:25633503

  13. Resilient workflows for computational mechanics platforms

    NASA Astrophysics Data System (ADS)

    Nguyên, Toàn; Trifan, Laurentiu; Désidéri, Jean-Antoine

    2010-06-01

    Workflow management systems have recently been the focus of much interest and many research and deployment for scientific applications worldwide [26, 27]. Their ability to abstract the applications by wrapping application codes have also stressed the usefulness of such systems for multidiscipline applications [23, 24]. When complex applications need to provide seamless interfaces hiding the technicalities of the computing infrastructures, their high-level modeling, monitoring and execution functionalities help giving production teams seamless and effective facilities [25, 31, 33]. Software integration infrastructures based on programming paradigms such as Python, Mathlab and Scilab have also provided evidence of the usefulness of such approaches for the tight coupling of multidisciplne application codes [22, 24]. Also high-performance computing based on multi-core multi-cluster infrastructures open new opportunities for more accurate, more extensive and effective robust multi-discipline simulations for the decades to come [28]. This supports the goal of full flight dynamics simulation for 3D aircraft models within the next decade, opening the way to virtual flight-tests and certification of aircraft in the future [23, 24, 29].

  14. Applications of Animal Research in the Behavioral Sciences: Effects of Chronic Exercise on Emotionality in Rats.

    ERIC Educational Resources Information Center

    Tharp, Gerald D.

    The psychological effects of exercise training are difficult to study in humans, but analogous emotionality changes in animals can be studied using simple measurements employed in emergence and open-field tests. The basis of these tests is that animals that are more emotional are more fearful when placed in a novel situation and will exhibit less…

  15. Standard Test Methods for Textile Composites

    NASA Technical Reports Server (NTRS)

    Masters, John E.; Portanova, Marc A.

    1996-01-01

    Standard testing methods for composite laminates reinforced with continuous networks of braided, woven, or stitched fibers have been evaluated. The microstructure of these textile' composite materials differs significantly from that of tape laminates. Consequently, specimen dimensions and loading methods developed for tape type composites may not be applicable to textile composites. To this end, a series of evaluations were made comparing testing practices currently used in the composite industry. Information was gathered from a variety of sources and analyzed to establish a series of recommended test methods for textile composites. The current practices established for laminated composite materials by ASTM and the MIL-HDBK-17 Committee were considered. This document provides recommended test methods for determining both in-plane and out-of-plane properties. Specifically, test methods are suggested for: unnotched tension and compression; open and filled hole tension; open hole compression; bolt bearing; and interlaminar tension. A detailed description of the material architectures evaluated is also provided, as is a recommended instrumentation practice.

  16. An Open Architecture to Support Social and Health Services in a Smart TV Environment.

    PubMed

    Costa, Carlos Rivas; Anido-Rifon, Luis E; Fernandez-Iglesias, Manuel J

    2017-03-01

    To design, implement, and test a solution to provide social and health services for the elderly at home based on smart TV technologies and access to all services. The architecture proposed is based on an open software platform and standard personal computing hardware. This provides great flexibility to develop new applications over the underlying infrastructure or to integrate new devices, for instance to monitor a broad range of vital signs in those cases where home monitoring is required. An actual system as a proof-of-concept was designed, implemented, and deployed. Applications range from social network clients to vital signs monitoring; from interactive TV contests to conventional online care applications such as medication reminders or telemedicine. In both cases, the results have been very positive, confirming the initial perception of the TV as a convenient, easy-to-use technology to provide social and health care. The TV set is a much more familiar computing interface for most senior users, and as a consequence, smart TVs become a most convenient solution for the design and implementation of applications and services targeted to this user group. This proposal has been tested in real setting with 62 senior people at their homes. Users included both individuals with experience using computers and others reluctant to them.

  17. Identification of Lilial as a fragrance sensitizer in a perfume by bioassay-guided chemical fractionation and structure-activity relationships.

    PubMed

    Arnau, E G; Andersen, K E; Bruze, M; Frosch, P J; Johansen, J D; Menné, T; Rastogi, S C; White, I R; Lepoittevin, J P

    2000-12-01

    Fragrance materials are among the most common causes of allergic contact dermatitis. The aim of this study was to identify in a perfume fragrance allergens not included in the fragrance mix, by use of bioassay-guided chemical fractionation and chemical analysis/structure-activity relationships (SARs). The basis for the investigation was a 45-year-old woman allergic to her own perfume. She had a negative patch test to the fragrance mix and agreed to participate in the study. Chemical fractionation of the perfume concentrate was used for repeated patch testing and/or repeated open application test on the pre-sensitized patient. The chemical composition of the fractions giving a positive patch-test response and repeated open application test reactions was obtained by gas chromatography-mass spectrometry. From the compounds identified, those that contained a "structural alert" in their chemical structure, indicating an ability to modify skin proteins and thus behave as a skin sensitizer, were tested on the patient. The patient reacted positively to the synthetic fragrance p-t-butyl-alpha-methylhydrocinnamic aldehyde (Lilial), a widely used fragrance compound not present in the fragrance mix. The combination of bioassay-guided chemical fractionation and chemical analysis/structure-activity relationships seems to be a valuable tool for the investigation of contact allergy to fragrance materials.

  18. Matching incomplete time series with dynamic time warping: an algorithm and an application to post-stroke rehabilitation.

    PubMed

    Tormene, Paolo; Giorgino, Toni; Quaglini, Silvana; Stefanelli, Mario

    2009-01-01

    The purpose of this study was to assess the performance of a real-time ("open-end") version of the dynamic time warping (DTW) algorithm for the recognition of motor exercises. Given a possibly incomplete input stream of data and a reference time series, the open-end DTW algorithm computes both the size of the prefix of reference which is best matched by the input, and the dissimilarity between the matched portions. The algorithm was used to provide real-time feedback to neurological patients undergoing motor rehabilitation. We acquired a dataset of multivariate time series from a sensorized long-sleeve shirt which contains 29 strain sensors distributed on the upper limb. Seven typical rehabilitation exercises were recorded in several variations, both correctly and incorrectly executed, and at various speeds, totaling a data set of 840 time series. Nearest-neighbour classifiers were built according to the outputs of open-end DTW alignments and their global counterparts on exercise pairs. The classifiers were also tested on well-known public datasets from heterogeneous domains. Nonparametric tests show that (1) on full time series the two algorithms achieve the same classification accuracy (p-value =0.32); (2) on partial time series, classifiers based on open-end DTW have a far higher accuracy (kappa=0.898 versus kappa=0.447;p<10(-5)); and (3) the prediction of the matched fraction follows closely the ground truth (root mean square <10%). The results hold for the motor rehabilitation and the other datasets tested, as well. The open-end variant of the DTW algorithm is suitable for the classification of truncated quantitative time series, even in the presence of noise. Early recognition and accurate class prediction can be achieved, provided that enough variance is available over the time span of the reference. Therefore, the proposed technique expands the use of DTW to a wider range of applications, such as real-time biofeedback systems.

  19. DEVELOPMENT OF AN ULTRASONIC INDIRECT BLOOD PRESSURE SENSING TECHNIQUE FOR AEROSPACE APPLICATION,

    DTIC Science & Technology

    with arterial opening motion, comparing systolic and diastolic pressures thus obtained to those acquired by auscultation and recording Korotkoff sounds...level airborne noise environments where auscultation techniques were not usable. Tests made with patients in shock showed performance of the

  20. Testing and modeling the influence of reclamation and control methods for reducing nonpoint mercury emissions associated with industrial open pit gold mines.

    PubMed

    Miller, Matthieu B; Gustin, Mae S

    2013-06-01

    Industrial gold mining is a significant source of mercury (Hg) emission to the atmosphere. To investigate ways to reduce these emissions, reclamation and dust and mercury control methods used at open pit gold mining operations in Nevada were studied in a laboratory setting. Using this information along with field data, and building off previous work, total annual Hg emissions were estimated for two active gold mines in northern Nevada. Results showed that capping mining waste materials with a low-Hg substrate can reduce Hg emissions from 50 to nearly 100%. The spraying of typical dust control solutions often results in higher Hg emissions, especially as materials dry after application. The concentrated application of a dithiocarbamate Hg control reagent appears to reduce Hg emissions, but further testing mimicking the actual distribution of this chemical within an active leach solution is needed to make a more definitive assessment.

  1. [Series: Medical Applications of the PHITS Code (2): Acceleration by Parallel Computing].

    PubMed

    Furuta, Takuya; Sato, Tatsuhiko

    2015-01-01

    Time-consuming Monte Carlo dose calculation becomes feasible owing to the development of computer technology. However, the recent development is due to emergence of the multi-core high performance computers. Therefore, parallel computing becomes a key to achieve good performance of software programs. A Monte Carlo simulation code PHITS contains two parallel computing functions, the distributed-memory parallelization using protocols of message passing interface (MPI) and the shared-memory parallelization using open multi-processing (OpenMP) directives. Users can choose the two functions according to their needs. This paper gives the explanation of the two functions with their advantages and disadvantages. Some test applications are also provided to show their performance using a typical multi-core high performance workstation.

  2. Openlobby: an open game server for lobby and matchmaking

    NASA Astrophysics Data System (ADS)

    Zamzami, E. M.; Tarigan, J. T.; Jaya, I.; Hardi, S. M.

    2018-03-01

    Online Multiplayer is one of the most essential feature in modern games. However, while developing a multiplayer feature can be done with a simple computer networking programming, creating a balanced multiplayer session requires more player management components such as game lobby and matchmaking system. Our objective is to develop OpenLobby, a server that available to be used by other developers to support their multiplayer application. The proposed system acts as a lobby and matchmaker where queueing players will be matched to other player according to a certain criteria defined by developer. The solution provides an application programing interface that can be used by developer to interact with the server. For testing purpose, we developed a game that uses the server as their multiplayer server.

  3. Test Control Center

    NASA Image and Video Library

    2000-10-25

    At the test observation periscope in the Test Control Center exhibit in StenniSphere at the John C. Stennis Space Center in Hancock County, Miss., visitors can observe a test of a Space Shuttle Main Engine exactly as test engineers might see it during a real engine test. The Test Control Center exhibit exactly simulates not only the test control environment, but also the procedure of testing a rocket engine. Designed to entertain while educating, StenniSphere includes informative dispays and exhibits from NASA's lead center for rocket propulsion and remote sensing applications. StenniSphere is open free of charge from 9 a.m. to 5 p.m. daily.

  4. 43 CFR 3816.2 - Application to open lands to location.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Application to open lands to location... LOCATION Mineral Locations in Reclamation Withdrawals § 3816.2 Application to open lands to location. Application to open lands to location under the Act may be filed by a person, association or corporation...

  5. 43 CFR 3816.2 - Application to open lands to location.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Application to open lands to location... LOCATION Mineral Locations in Reclamation Withdrawals § 3816.2 Application to open lands to location. Application to open lands to location under the Act may be filed by a person, association or corporation...

  6. Energy Systems Integration News - September 2016 | Energy Systems

    Science.gov Websites

    , Smarter Grid Solutions demonstrated a new distributed energy resources (DER) software control platform utility interconnections require distributed generation (DG) devices to disconnect from the grid during OpenFMB distributed applications on the microgrid test site to locally optimize renewable energy resources

  7. Testing of Cerex Open-Path Ultraviolet Differential Optical Absorption Spectroscopy Systems for Fenceline Monitoring Applications

    EPA Science Inventory

    Development of cost-effective, time-resolved fenceline measurement methods that facilitate improved emissions mitigation strategies is of growing interest to both industry and regulators. Ground-based optical remote sensing (ORS) is a well-known class of technical approaches use...

  8. Testing of Cerex Open-Path Ultraviolet Differential Optical Absorption Spectroscopy System for Fenceline Monitoring Applications

    EPA Science Inventory

    Development of cost-effective, time-resolved fenceline measurement methods that facilitate improved emissions mitigation strategies is of growing interest to both industry and regulators. Ground-based optical remote sensing (ORS) is a well-known class of technical approaches use...

  9. Testing of Cerex Open Path Ultraviolet Differential Optical Absorption Spectroscopy Systems for Fenceline Monitoring Applications

    EPA Science Inventory

    Industrial facilities, energy production, and refining operations can be significant sources of gas-phase air pollutants. Some industrial emissions originate from fugitive sources (leaks) or process malfunctions and can be mitigated if identified. In recent amendments to the Nati...

  10. Assessing and Testing Hydrokinetic Turbine Performance and Effects on Open Channel Hydrodynamics: An Irrigation Canal Case Study.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gunawan, Budi; Neary, Vincent Sinclair; Mortensen, Josh

    Hydrokinetic energy from flowing water in open channels has the potential to support local electricity needs with lower regulatory or capital investment than impounding water with more conventional means. MOU agencies involved in federal hydropower development have identified the need to better understand the opportunities for hydrokinetic (HK) energy development within existing canal systems that may already have integrated hydropower plants. This document provides an overview of the main considerations, tools, and assessment methods, for implementing field tests in an open-channel water system to characterize current energy converter (CEC) device performance and hydrodynamic effects. It describes open channel processes relevantmore » to their HK site and perform pertinent analyses to guide siting and CEC layout design, with the goal of streamlining the evaluation process and reducing the risk of interfering with existing uses of the site. This document outlines key site parameters of interest and effective tools and methods for measurement and analysis with examples drawn from the Roza Main Canal, in Yakima, WA to illustrate a site application.« less

  11. Verification Tools Secure Online Shopping, Banking

    NASA Technical Reports Server (NTRS)

    2010-01-01

    Just like rover or rocket technology sent into space, the software that controls these technologies must be extensively tested to ensure reliability and effectiveness. Ames Research Center invented the open-source Java Pathfinder (JPF) toolset for the deep testing of Java-based programs. Fujitsu Labs of America Inc., based in Sunnyvale, California, improved the capabilities of the JPF Symbolic Pathfinder tool, establishing the tool as a means of thoroughly testing the functionality and security of Web-based Java applications such as those used for Internet shopping and banking.

  12. Application research of Ganglia in Hadoop monitoring and management

    NASA Astrophysics Data System (ADS)

    Li, Gang; Ding, Jing; Zhou, Lixia; Yang, Yi; Liu, Lei; Wang, Xiaolei

    2017-03-01

    There are many applications of Hadoop System in the field of large data, cloud computing. The test bench of storage and application in seismic network at Earthquake Administration of Tianjin use with Hadoop system, which is used the open source software of Ganglia to operate and monitor. This paper reviews the function, installation and configuration process, application effect of operating and monitoring in Hadoop system of the Ganglia system. It briefly introduces the idea and effect of Nagios software monitoring Hadoop system. It is valuable for the industry in the monitoring system of cloud computing platform.

  13. Multi-threaded integration of HTC-Vive and MeVisLab

    NASA Astrophysics Data System (ADS)

    Gunacker, Simon; Gall, Markus; Schmalstieg, Dieter; Egger, Jan

    2018-03-01

    This work presents how Virtual Reality (VR) can easily be integrated into medical applications via a plugin for a medical image processing framework called MeVisLab. A multi-threaded plugin has been developed using OpenVR, a VR library that can be used for developing vendor and platform independent VR applications. The plugin is tested using the HTC Vive, a head-mounted display developed by HTC and Valve Corporation.

  14. Area-Wide Ground Applications of Bacillus thuringiensis var. israelensis for the Control of Aedes albopictus in Residential Neighborhoods: From Optimization to Operation

    PubMed Central

    Williams, Gregory M.; Faraji, Ary; Unlu, Isik; Healy, Sean P.; Farooq, Muhammad; Gaugler, Randy; Hamilton, George; Fonseca, Dina M.

    2014-01-01

    The increasing range of Aedes albopictus, the Asian tiger mosquito, in the USA and the threat of chikungunya and dengue outbreaks vectored by this species have necessitated novel approaches to control this peridomestic mosquito. Conventional methods such as adulticiding provide temporary relief, but fail to manage this pest on a sustained basis. We explored the use of cold aerosol foggers and misting machines for area-wide applications of Bacillus thuringiensis var. israelensis (VectoBac WDG) as a larvicide targeting Aedes albopictus. During 2010–2013 we performed initially open field trials and then 19 operational area-wide applications in urban and suburban residential areas in northeastern USA to test three truck-mounted sprayers at two application rates. Area-wide applications of WDG in open field conditions at 400 and 800 g/ha killed on average 87% of tested larvae. Once techniques were optimized in residential areas, applications with a Buffalo Turbine Mist Sprayer at a rate of 800 g/ha, the best combination, consistently provided over 90% mortality. Importantly, there was no significant decrease in efficacy with distance from the spray line even in blocks of row homes with trees and bushes in the backyards. Under laboratory conditions Bti deposition in bioassay cups during the operational trials resulted in over 6 weeks of residual control. Our results demonstrate that area-wide truck mounted applications of WDG can effectively suppress Ae. albopictus larvae and should be used in integrated mosquito management approaches to control this nuisance pest and disease vector. PMID:25329314

  15. Area-wide ground applications of Bacillus thuringiensis var. israelensis for the control of Aedes albopictus in residential neighborhoods: from optimization to operation.

    PubMed

    Williams, Gregory M; Faraji, Ary; Unlu, Isik; Healy, Sean P; Farooq, Muhammad; Gaugler, Randy; Hamilton, George; Fonseca, Dina M

    2014-01-01

    The increasing range of Aedes albopictus, the Asian tiger mosquito, in the USA and the threat of chikungunya and dengue outbreaks vectored by this species have necessitated novel approaches to control this peridomestic mosquito. Conventional methods such as adulticiding provide temporary relief, but fail to manage this pest on a sustained basis. We explored the use of cold aerosol foggers and misting machines for area-wide applications of Bacillus thuringiensis var. israelensis (VectoBac WDG) as a larvicide targeting Aedes albopictus. During 2010-2013 we performed initially open field trials and then 19 operational area-wide applications in urban and suburban residential areas in northeastern USA to test three truck-mounted sprayers at two application rates. Area-wide applications of WDG in open field conditions at 400 and 800 g/ha killed on average 87% of tested larvae. Once techniques were optimized in residential areas, applications with a Buffalo Turbine Mist Sprayer at a rate of 800 g/ha, the best combination, consistently provided over 90% mortality. Importantly, there was no significant decrease in efficacy with distance from the spray line even in blocks of row homes with trees and bushes in the backyards. Under laboratory conditions Bti deposition in bioassay cups during the operational trials resulted in over 6 weeks of residual control. Our results demonstrate that area-wide truck mounted applications of WDG can effectively suppress Ae. albopictus larvae and should be used in integrated mosquito management approaches to control this nuisance pest and disease vector.

  16. Assessment of anxiety in open field and elevated plus maze using infrared thermography.

    PubMed

    Lecorps, Benjamin; Rödel, Heiko G; Féron, Christophe

    2016-04-01

    Due to their direct inaccessibility, affective states are classically assessed by gathering concomitant physiological and behavioral measures. Although such a dual approach to assess emotional states is frequently used in different species including humans, the invasiveness of procedures for physiological recordings particularly in smaller-sized animals strongly restricts their application. We used infrared thermography, a non-invasive method, to assess physiological arousal during open field and elevated plus maze tests in mice. By measuring changes in surface temperature indicative of the animals' emotional response, we aimed to improve the inherently limited and still controversial information provided by behavioral parameters commonly used in these tests. Our results showed significant and consistent thermal responses during both tests, in accordance with classical physiological responses occurring in stressful situations. Besides, we found correlations between these thermal responses and the occurrence of anxiety-related behaviors. Furthermore, initial temperatures measured at the start of each procedure (open field, elevated plus maze), which can be interpreted as a measure of the animals' initial physiological arousal, predicted the levels of activity and of anxiety-related behaviors displayed during the tests. Our results stress the strong link between physiological correlates of emotions and behaviors expressed during unconditioned fear tests. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Software for MR image overlay guided needle insertions: the clinical translation process

    NASA Astrophysics Data System (ADS)

    Ungi, Tamas; U-Thainual, Paweena; Fritz, Jan; Iordachita, Iulian I.; Flammang, Aaron J.; Carrino, John A.; Fichtinger, Gabor

    2013-03-01

    PURPOSE: Needle guidance software using augmented reality image overlay was translated from the experimental phase to support preclinical and clinical studies. Major functional and structural changes were needed to meet clinical requirements. We present the process applied to fulfill these requirements, and selected features that may be applied in the translational phase of other image-guided surgical navigation systems. METHODS: We used an agile software development process for rapid adaptation to unforeseen clinical requests. The process is based on iterations of operating room test sessions, feedback discussions, and software development sprints. The open-source application framework of 3D Slicer and the NA-MIC kit provided sufficient flexibility and stable software foundations for this work. RESULTS: All requirements were addressed in a process with 19 operating room test iterations. Most features developed in this phase were related to workflow simplification and operator feedback. CONCLUSION: Efficient and affordable modifications were facilitated by an open source application framework and frequent clinical feedback sessions. Results of cadaver experiments show that software requirements were successfully solved after a limited number of operating room tests.

  18. Parallelization of interpolation, solar radiation and water flow simulation modules in GRASS GIS using OpenMP

    NASA Astrophysics Data System (ADS)

    Hofierka, Jaroslav; Lacko, Michal; Zubal, Stanislav

    2017-10-01

    In this paper, we describe the parallelization of three complex and computationally intensive modules of GRASS GIS using the OpenMP application programming interface for multi-core computers. These include the v.surf.rst module for spatial interpolation, the r.sun module for solar radiation modeling and the r.sim.water module for water flow simulation. We briefly describe the functionality of the modules and parallelization approaches used in the modules. Our approach includes the analysis of the module's functionality, identification of source code segments suitable for parallelization and proper application of OpenMP parallelization code to create efficient threads processing the subtasks. We document the efficiency of the solutions using the airborne laser scanning data representing land surface in the test area and derived high-resolution digital terrain model grids. We discuss the performance speed-up and parallelization efficiency depending on the number of processor threads. The study showed a substantial increase in computation speeds on a standard multi-core computer while maintaining the accuracy of results in comparison to the output from original modules. The presented parallelization approach showed the simplicity and efficiency of the parallelization of open-source GRASS GIS modules using OpenMP, leading to an increased performance of this geospatial software on standard multi-core computers.

  19. FUNDAMENTAL PROPERTIES OF ULTRA HIGH PERFORMANCE-STRAIN HARDENING CEMENTITIOUS COMPOSITES AND USAGE FOR REPAIR

    NASA Astrophysics Data System (ADS)

    Kunieda, Minoru; Shimizu, Kosuke; Eguchi, Teruyuki; Ueda, Naoshi; Nakamura, Hikaru

    This paper presents the fundamental properties of Ultra High Performance-Strain Hardening Cementitious Composites (UHP-SHCC), which were depeloped for repair applications. In particular, mechanical properties such as tensile response, shrinkage and bond strength were investigated experimentally. Protective performance of the material such as air permeability, water permeability and penetration of chloride ion was also confirmed comparing to that of ordinary concrete. This paper also introduces the usage of the material in repair of concrete st ructures. Laboratory tests concerining the deterioration induced by corrosion were conducted. The UHP-SHCC that coverd the RC beam resisted not only crack opening along the rebar due to corrosion but also crack opening due to loading tests.

  20. Studies of silicon pn junction solar cells

    NASA Technical Reports Server (NTRS)

    Lindholm, F. A.; Neugroschel, A.

    1977-01-01

    Modifications of the basic Shockley equations that result from the random and nonrandom spatial variations of the chemical composition of a semiconductor were developed. These modifications underlie the existence of the extensive emitter recombination current that limits the voltage over the open circuit of solar cells. The measurement of parameters, series resistance and the base diffusion length is discussed. Two methods are presented for establishing the energy bandgap narrowing in the heavily-doped emitter region. Corrections that can be important in the application of one of these methods to small test cells are examined. Oxide-charge-induced high-low-junction emitter (OCI-HLE) test cells which exhibit considerably higher voltage over the open circuit than was previously seen in n-on-p solar cells are described.

  1. An Offline-Online Android Application for Hazard Event Mapping Using WebGIS Open Source Technologies

    NASA Astrophysics Data System (ADS)

    Olyazadeh, Roya; Jaboyedoff, Michel; Sudmeier-Rieux, Karen; Derron, Marc-Henri; Devkota, Sanjaya

    2016-04-01

    Nowadays, Free and Open Source Software (FOSS) plays an important role in better understanding and managing disaster risk reduction around the world. National and local government, NGOs and other stakeholders are increasingly seeking and producing data on hazards. Most of the hazard event inventories and land use mapping are based on remote sensing data, with little ground truthing, creating difficulties depending on the terrain and accessibility. Open Source WebGIS tools offer an opportunity for quicker and easier ground truthing of critical areas in order to analyse hazard patterns and triggering factors. This study presents a secure mobile-map application for hazard event mapping using Open Source WebGIS technologies such as Postgres database, Postgis, Leaflet, Cordova and Phonegap. The objectives of this prototype are: 1. An Offline-Online android mobile application with advanced Geospatial visualisation; 2. Easy Collection and storage of events information applied services; 3. Centralized data storage with accessibility by all the service (smartphone, standard web browser); 4. Improving data management by using active participation in hazard event mapping and storage. This application has been implemented as a low-cost, rapid and participatory method for recording impacts from hazard events and includes geolocation (GPS data and Internet), visualizing maps with overlay of satellite images, viewing uploaded images and events as cluster points, drawing and adding event information. The data can be recorded in offline (Android device) or online version (all browsers) and consequently uploaded through the server whenever internet is available. All the events and records can be visualized by an administrator and made public after approval. Different user levels can be defined to access the data for communicating the information. This application was tested for landslides in post-earthquake Nepal but can be used for any other type of hazards such as flood, avalanche, etc. Keywords: Offline, Online, WebGIS Open source, Android, Hazard Event Mapping

  2. 49 CFR 180.411 - Acceptable results of tests and inspections.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... than that prescribed in the applicable specification. (b) Dents, cuts, digs and gouges. For evaluation... minimum thickness remaining beneath a cut, dig, or gouge may not be less than that prescribed in the... to hazardous materials service. (e) Relief valves. Any pressure relief valve that fails to open and...

  3. Unit Operation Experiment Linking Classroom with Industrial Processing

    ERIC Educational Resources Information Center

    Benson, Tracy J.; Richmond, Peyton C.; LeBlanc, Weldon

    2013-01-01

    An industrial-type distillation column, including appropriate pumps, heat exchangers, and automation, was used as a unit operations experiment to provide a link between classroom teaching and real-world applications. Students were presented with an open-ended experiment where they defined the testing parameters to solve a generalized problem. The…

  4. Manned remote work station development article, executive summary

    NASA Technical Reports Server (NTRS)

    1979-01-01

    The mission requirements for the manned remote work station (MRWS) flight article and the manned remote work station open cherry picker development test article is defined. Considerations are given for the near, mid, and far term use of the MRWS with emphasis on its ultimate application: constructing the Solar Power Satellite.

  5. CanOpen on RASTA: The Integration of the CanOpen IP Core in the Avionics Testbed

    NASA Astrophysics Data System (ADS)

    Furano, Gianluca; Guettache, Farid; Magistrati, Giorgio; Tiotto, Gabriele; Ortega, Carlos Urbina; Valverde, Alberto

    2013-08-01

    This paper presents the work done within the ESA Estec Data Systems Division, targeting the integration of the CanOpen IP Core with the existing Reference Architecture Test-bed for Avionics (RASTA). RASTA is the reference testbed system of the ESA Avionics Lab, designed to integrate the main elements of a typical Data Handling system. It aims at simulating a scenario where a Mission Control Center communicates with on-board computers and systems through a TM/TC link, thus providing the data management through qualified processors and interfaces such as Leon2 core processors, CAN bus controllers, MIL-STD-1553 and SpaceWire. This activity aims at the extension of the RASTA with two boards equipped with HurriCANe controller, acting as CANOpen slaves. CANOpen software modules have been ported on the RASTA system I/O boards equipped with Gaisler GR-CAN controller and acts as master communicating with the CCIPC boards. CanOpen serves as upper application layer for based on CAN defined within the CAN-in-Automation standard and can be regarded as the definitive standard for the implementation of CAN-based systems solutions. The development and integration of CCIPC performed by SITAEL S.p.A., is the first application that aims to bring the CANOpen standard for space applications. The definition of CANOpen within the European Cooperation for Space Standardization (ECSS) is under development.

  6. The effect of foot plantar massage on balance and functional reach in patients with type II diabetes.

    PubMed

    Tütün Yümin, Eylem; Şimşek, Tülay Tarsuslu; Sertel, Meral; Ankaralı, Handan; Yumin, Murat

    2017-02-01

    The aim of this study was to investigate the effect of manual foot plantar massage (classic and friction massage) on functional mobility level, balance, and functional reach in patients with type II diabetes mellitus (T2 DM). A total of 38 subjects diagnosed with T2 DM were included in the study. A healthy control group could not be formed in this study. After the subjects' socio-demographic data were obtained, Timed Up & Go (TUG) Test, functional reach test (FRT), one-leg standing test with eyes open-closed, and Visual Analogue Scale (VAS) to measure foot pain intensity were performed. The results were also divided and assessed in three groups according to the ages of the individuals (40-54, 55-64, and 65 and over). As a result of statistical analysis, a difference was found in the values obtained from TUG, FRT, and one-leg standing test with eyes open and closed (p < 0.05). Following the massage, TUG values significantly decreased comparison with those before the massage, whereas the values of FRT and one-leg standing test with eyes open and closed significantly increased compared with those before the massage (p > 0.05). According to age groups, there were statistical differences (p < 0.05) between the TUG, one-leg standing test with eyes open and closed test values of the individuals before and after the massage. The results of our study indicated that application of plantar massage to patients with T2 DM caused an improvement in balance, functional mobility, and functional reach values. An increase in body balance and functional mobility may explain the improvement in TUG. Foot massage to be added to rehabilitation exercise programs of DM patients will be important in improving balance and mobility of patients.

  7. CheapStat: an open-source, "do-it-yourself" potentiostat for analytical and educational applications.

    PubMed

    Rowe, Aaron A; Bonham, Andrew J; White, Ryan J; Zimmer, Michael P; Yadgar, Ramsin J; Hobza, Tony M; Honea, Jim W; Ben-Yaacov, Ilan; Plaxco, Kevin W

    2011-01-01

    Although potentiostats are the foundation of modern electrochemical research, they have seen relatively little application in resource poor settings, such as undergraduate laboratory courses and the developing world. One reason for the low penetration of potentiostats is their cost, as even the least expensive commercially available laboratory potentiostats sell for more than one thousand dollars. An inexpensive electrochemical workstation could thus prove useful in educational labs, and increase access to electrochemistry-based analytical techniques for food, drug and environmental monitoring. With these motivations in mind, we describe here the CheapStat, an inexpensive (<$80), open-source (software and hardware), hand-held potentiostat that can be constructed by anyone who is proficient at assembling circuits. This device supports a number of potential waveforms necessary to perform cyclic, square wave, linear sweep and anodic stripping voltammetry. As we demonstrate, it is suitable for a wide range of applications ranging from food- and drug-quality testing to environmental monitoring, rapid DNA detection, and educational exercises. The device's schematics, parts lists, circuit board layout files, sample experiments, and detailed assembly instructions are available in the supporting information and are released under an open hardware license.

  8. Closed-loop feedback control for microfluidic systems through automated capacitive fluid height sensing.

    PubMed

    Soenksen, L R; Kassis, T; Noh, M; Griffith, L G; Trumper, D L

    2018-03-13

    Precise fluid height sensing in open-channel microfluidics has long been a desirable feature for a wide range of applications. However, performing accurate measurements of the fluid level in small-scale reservoirs (<1 mL) has proven to be an elusive goal, especially if direct fluid-sensor contact needs to be avoided. In particular, gravity-driven systems used in several microfluidic applications to establish pressure gradients and impose flow remain open-loop and largely unmonitored due to these sensing limitations. Here we present an optimized self-shielded coplanar capacitive sensor design and automated control system to provide submillimeter fluid-height resolution (∼250 μm) and control of small-scale open reservoirs without the need for direct fluid contact. Results from testing and validation of our optimized sensor and system also suggest that accurate fluid height information can be used to robustly characterize, calibrate and dynamically control a range of microfluidic systems with complex pumping mechanisms, even in cell culture conditions. Capacitive sensing technology provides a scalable and cost-effective way to enable continuous monitoring and closed-loop feedback control of fluid volumes in small-scale gravity-dominated wells in a variety of microfluidic applications.

  9. CheapStat: An Open-Source, “Do-It-Yourself” Potentiostat for Analytical and Educational Applications

    PubMed Central

    Rowe, Aaron A.; Bonham, Andrew J.; White, Ryan J.; Zimmer, Michael P.; Yadgar, Ramsin J.; Hobza, Tony M.; Honea, Jim W.; Ben-Yaacov, Ilan; Plaxco, Kevin W.

    2011-01-01

    Although potentiostats are the foundation of modern electrochemical research, they have seen relatively little application in resource poor settings, such as undergraduate laboratory courses and the developing world. One reason for the low penetration of potentiostats is their cost, as even the least expensive commercially available laboratory potentiostats sell for more than one thousand dollars. An inexpensive electrochemical workstation could thus prove useful in educational labs, and increase access to electrochemistry-based analytical techniques for food, drug and environmental monitoring. With these motivations in mind, we describe here the CheapStat, an inexpensive (<$80), open-source (software and hardware), hand-held potentiostat that can be constructed by anyone who is proficient at assembling circuits. This device supports a number of potential waveforms necessary to perform cyclic, square wave, linear sweep and anodic stripping voltammetry. As we demonstrate, it is suitable for a wide range of applications ranging from food- and drug-quality testing to environmental monitoring, rapid DNA detection, and educational exercises. The device's schematics, parts lists, circuit board layout files, sample experiments, and detailed assembly instructions are available in the supporting information and are released under an open hardware license. PMID:21931613

  10. Open Source Dataturbine (OSDT) Android Sensorpod in Environmental Observing Systems

    NASA Astrophysics Data System (ADS)

    Fountain, T. R.; Shin, P.; Tilak, S.; Trinh, T.; Smith, J.; Kram, S.

    2014-12-01

    The OSDT Android SensorPod is a custom-designed mobile computing platform for assembling wireless sensor networks for environmental monitoring applications. Funded by an award from the Gordon and Betty Moore Foundation, the OSDT SensorPod represents a significant technological advance in the application of mobile and cloud computing technologies to near-real-time applications in environmental science, natural resources management, and disaster response and recovery. It provides a modular architecture based on open standards and open-source software that allows system developers to align their projects with industry best practices and technology trends, while avoiding commercial vendor lock-in to expensive proprietary software and hardware systems. The integration of mobile and cloud-computing infrastructure represents a disruptive technology in the field of environmental science, since basic assumptions about technology requirements are now open to revision, e.g., the roles of special purpose data loggers and dedicated site infrastructure. The OSDT Android SensorPod was designed with these considerations in mind, and the resulting system exhibits the following characteristics - it is flexible, efficient and robust. The system was developed and tested in the three science applications: 1) a fresh water limnology deployment in Wisconsin, 2) a near coastal marine science deployment at the UCSD Scripps Pier, and 3) a terrestrial ecological deployment in the mountains of Taiwan. As part of a public education and outreach effort, a Facebook page with daily ocean pH measurements from the UCSD Scripps pier was developed. Wireless sensor networks and the virtualization of data and network services is the future of environmental science infrastructure. The OSDT Android SensorPod was designed and developed to harness these new technology developments for environmental monitoring applications.

  11. Pika: A snow science simulation tool built using the open-source framework MOOSE

    NASA Astrophysics Data System (ADS)

    Slaughter, A.; Johnson, M.

    2017-12-01

    The Department of Energy (DOE) is currently investing millions of dollars annually into various modeling and simulation tools for all aspects of nuclear energy. An important part of this effort includes developing applications based on the open-source Multiphysics Object Oriented Simulation Environment (MOOSE; mooseframework.org) from Idaho National Laboratory (INL).Thanks to the efforts of the DOE and outside collaborators, MOOSE currently contains a large set of physics modules, including phase-field, level set, heat conduction, tensor mechanics, Navier-Stokes, fracture and crack propagation (via the extended finite-element method), flow in porous media, and others. The heat conduction, tensor mechanics, and phase-field modules, in particular, are well-suited for snow science problems. Pika--an open-source MOOSE-based application--is capable of simulating both 3D, coupled nonlinear continuum heat transfer and large-deformation mechanics applications (such as settlement) and phase-field based micro-structure applications. Additionally, these types of problems may be coupled tightly in a single solve or across length and time scales using a loosely coupled Picard iteration approach. In addition to the wide range of physics capabilities, MOOSE-based applications also inherit an extensible testing framework, graphical user interface, and documentation system; tools that allow MOOSE and other applications to adhere to nuclear software quality standards. The snow science community can learn from the nuclear industry and harness the existing effort to build simulation tools that are open, modular, and share a common framework. In particular, MOOSE-based multiphysics solvers are inherently parallel, dimension agnostic, adaptive in time and space, fully coupled, and capable of interacting with other applications. The snow science community should build on existing tools to enable collaboration between researchers and practitioners throughout the world, and advance the state-of-the-art in line with other scientific research efforts.

  12. Testing and Validating Machine Learning Classifiers by Metamorphic Testing☆

    PubMed Central

    Xie, Xiaoyuan; Ho, Joshua W. K.; Murphy, Christian; Kaiser, Gail; Xu, Baowen; Chen, Tsong Yueh

    2011-01-01

    Machine Learning algorithms have provided core functionality to many application domains - such as bioinformatics, computational linguistics, etc. However, it is difficult to detect faults in such applications because often there is no “test oracle” to verify the correctness of the computed outputs. To help address the software quality, in this paper we present a technique for testing the implementations of machine learning classification algorithms which support such applications. Our approach is based on the technique “metamorphic testing”, which has been shown to be effective to alleviate the oracle problem. Also presented include a case study on a real-world machine learning application framework, and a discussion of how programmers implementing machine learning algorithms can avoid the common pitfalls discovered in our study. We also conduct mutation analysis and cross-validation, which reveal that our method has high effectiveness in killing mutants, and that observing expected cross-validation result alone is not sufficiently effective to detect faults in a supervised classification program. The effectiveness of metamorphic testing is further confirmed by the detection of real faults in a popular open-source classification program. PMID:21532969

  13. Fundamental and assessment of concrete structure monitoring by using acoustic emission technique testing: A review

    NASA Astrophysics Data System (ADS)

    Desa, M. S. M.; Ibrahim, M. H. W.; Shahidan, S.; Ghadzali, N. S.; Misri, Z.

    2018-04-01

    Acoustic emission (AE) technique is one of the non-destructive (NDT) testing, where it can be used to determine the damage of concrete structures such as crack, corrosion, stability, sensitivity, as structure monitoring and energy formed within cracking opening growth in the concrete structure. This article gives a comprehensive review of the acoustic emission (AE) technique testing due to its application in concrete structure for structural health monitoring (SHM). Assessment of AE technique used for structural are reviewed to give the perception of its structural engineering such as dam, bridge and building, where the previous research has been reviewed based on AE application. The assessment of AE technique focusing on basic fundamental of parametric and signal waveform analysis during analysis process and its capability in structural monitoring. Moreover, the assessment and application of AE due to its function have been summarized and highlighted for future references

  14. Deployment of Directory Service for IEEE N Bus Test System Information

    NASA Astrophysics Data System (ADS)

    Barman, Amal; Sil, Jaya

    2008-10-01

    Exchanging information over Internet and Intranet becomes a defacto standard in computer applications, among various users and organizations. Distributed system study, e-governance etc require transparent information exchange between applications, constituencies, manufacturers, and vendors. To serve these purposes database system is needed for storing system data and other relevant information. Directory service, which is a specialized database along with access protocol, could be the single solution since it runs over TCP/IP, supported by all POSIX compliance platforms and is based on open standard. This paper describes a way to deploy directory service, to store IEEE n bus test system data and integrating load flow program with it.

  15. Development and Preliminary Feasibility Study of a Brief Behavioral Activation Mobile Application (Behavioral Apptivation) to Be Used in Conjunction With Ongoing Therapy.

    PubMed

    Dahne, Jennifer; Kustanowitz, Jacob; Lejuez, C W

    2018-02-01

    Depressive symptoms are the most frequently treated psychiatric condition in the United States. Brief behavioral activation treatment for depression (BATD) is a popular, evidence-based psychotherapy with strong research support for the treatment of depression. In this paper, we describe the development and initial pilot feasibility testing of a BATD mobile application (Behavioral Apptivation) to be used by patients and therapists in conjunction with BATD therapy. We present information regarding the app development process as well as results from a small open-label feasibility trial of the app utilized in conjunction with individual BATD. We include a case series from the open-label trial highlighting how Behavioral Apptivation can be utilized in clinical practice.

  16. Assessment of Various Remote Sensing Technologies in Biomass and Nitrogen Content Estimation Using AN Agricultural Test Field

    NASA Astrophysics Data System (ADS)

    Näsi, R.; Viljanen, N.; Kaivosoja, J.; Hakala, T.; Pandžić, M.; Markelin, L.; Honkavaara, E.

    2017-10-01

    Multispectral and hyperspectral imaging is usually acquired by satellite and aircraft platforms. Recently, miniaturized hyperspectral 2D frame cameras have showed great potential to precise agriculture estimations and they are feasible to combine with lightweight platforms, such as drones. Drone platform is a flexible tool for remote sensing applications with environment and agriculture. The assessment and comparison of different platforms such as satellite, aircraft and drones with different sensors, such as hyperspectral and RGB cameras is an important task in order to understand the potential of the data provided by these equipment and to select the most appropriate according to the user applications and requirements. In this context, open and permanent test fields are very significant and helpful experimental environment, since they provide a comparative data for different platforms, sensors and users, allowing multi-temporal analyses as well. Objective of this work was to investigate the feasibility of an open permanent test field in context of precision agriculture. Satellite (Sentinel-2), aircraft and drones with hyperspectral and RGB cameras were assessed in this study to estimate biomass, using linear regression models and in-situ samples. Spectral data and 3D information were used and compared in different combinations to investigate the quality of the models. The biomass estimation accuracies using linear regression models were better than 90 % for the drone based datasets. The results showed that the use of spectral and 3D features together improved the estimation model. However, estimation of nitrogen content was less accurate with the evaluated remote sensing sensors. The open and permanent test field showed to be suitable to provide an accurate and reliable reference data for the commercial users and farmers.

  17. Expectancy of an open-book test decreases performance on a delayed closed-book test.

    PubMed

    Agarwal, Pooja K; Roediger, Henry L

    2011-11-01

    Two experiments examined the influence of practice with, and the expectancy of, open-book tests (students viewed studied material while taking the test) versus closed-book tests (students completed the test without viewing the studied material) on delayed retention and transfer. Using GRE materials specifically designed for open-book testing, participants studied passages and then took initial open- or closed-book tests. Open-book testing led to better initial performance than closed-book testing, but on a delayed criterial (closed-book) test both types of testing produced similar retention after a two-day delay in Experiment 1. In Experiment 2 participants were informed in advance about the type of delayed criterial test to expect (open- or closed-book). Expecting an open-book test (relative to a closed-book test) decreased participants' time spent studying and their delayed test performance on closed-book comprehension and transfer tests, demonstrating that test expectancy can influence long-term learning. Expectancy of open-book tests may impair long-term retention and transfer compared to closed-book tests, despite superior initial performance on open-book tests and students' preference for open-book tests.

  18. Application of Toxicity Identification and Evaluation Procedures for Dredged Material Management

    DTIC Science & Technology

    2017-02-01

    that may pose a risk to human health and the environment. The potential for risk ultimately depends on the final disposition of the dredged material... human health and ecological receptors. This information is also useful when evaluating dredged material for open water disposal since it could eliminate...and potential for exposure to humans or ecological receptors. The Inland Testing and Ocean Disposal Manuals establish a multi-step testing protocol

  19. 46 CFR 308.506 - Application for an Open Cargo Policy.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false Application for an Open Cargo Policy. 308.506 Section 308.506 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Open Policy War Risk Cargo Insurance § 308.506 Application for an Open...

  20. An assessment of the variability in performance of wet atmospheric deposition samplers

    USGS Publications Warehouse

    Graham, R.C.; Robertson, J.K.; Obal, John

    1987-01-01

    The variability in performance of two brands of wet/dry atmospheric deposition samplers were compared for 1 year at a sincle site. A total of nine samplers were used. Samples were collected weekly and analyzed for pH, specific conductance, common chemical constituents, and sample volume. Additionally, data on the duration of each sampler opening were recorded using a microdatalogger. These data disprove the common perception that samplers remain open throughout a precipitation event. The sensitivity of sampler sensors within the range tested did not have a defineable impact on sample collection. The nonnormal distribution within the data set necessitated application of the nonparametric Friedman Test to assess comparability of sample chemical composition and volume between and within sampler brands. Statistically significant differences existed for most comparisons, however the test did not permit quantification of their magnitudes. Differences in analyte concentrations between samplers were small. (USGS)

  1. 75 FR 50986 - Notice of Contract Proposal (NOCP) for Payments to Eligible Advanced Biofuel Producers

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-18

    ... remaining available Fiscal Year 2009 program funds. This Notice opens an application window for certain... opening a new application window from August 18, 2010 through September 17, 2010 to accept applications... opening a new application window to accept additional applications for the remaining available Fiscal Year...

  2. Modified short-term guinea pig sensitization tests for detecting contact allergens as an alternative to the conventional test.

    PubMed

    Yanagi, M; Hoya, M; Mori, M; Katsumura, Y

    2001-03-01

    The conventional adjuvant and patch test (APT) method of guinea pig sensitization testing was modified in 2 ways, s-APT and s-APT(2), in order to shorten the test period. These short-term test methods consist of 72-h closed application of test material with intradermal injection of emulsified Freund's complete adjuvant (E-FCA) for 1st induction, 48-h closed application of test material with (s-APT) or without (s-APT(2)) intradermal injection of E-FCA on the 7th day for 2nd induction, and open application on the 14th day for challenge. They were compared with conventional APT by using 8 allergenic chemicals (formaldehyde, nickel sulfate, cobalt sulfate, ethyl-p-aminobenzoate (benzocaine), isoeugenol, 2-mercaptobenzothiazole, 2,4-dinitrochlorobenzene (DNCB) and 1-phenylazo-2-naphthol (Sudan I)). The short-term methods gave similar results to those of conventional APT in terms of mean response, sensitization rate and sensitization potency (challenge concentration that induces a mean response equal to 1.0). Thus, our short-term methods, which are capable of evaluating skin sensitization within 17 days, are sufficiently sensitive to detect potentially hazardous contact allergens.

  3. Effects of weld residual stresses on crack-opening area analysis of pipes for LBB applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dong, P.; Rahman, S.; Wilkowski, G.

    1997-04-01

    This paper summarizes four different studies undertaken to evaluate the effects of weld residual stresses on the crack-opening behavior of a circumferential through-wall crack in the center of a girth weld. The effect of weld residual stress on the crack-opening-area and leak-rate analyses of a pipe is not well understood. There are no simple analyses to account for these effects, and, therefore, they are frequently neglected. The four studies involved the following efforts: (1) Full-field thermoplastic finite element residual stress analyses of a crack in the center of a girth weld, (2) A comparison of the crack-opening displacements from amore » full-field thermoplastic residual stress analysis with a crack-face pressure elastic stress analysis to determine the residual stress effects on the crack-opening displacement, (3) The effects of hydrostatic testing on the residual stresses and the resulting crack-opening displacement, and (4) The effect of residual stresses on crack-opening displacement with different normal operating stresses.« less

  4. Brokered virtual hubs for facilitating access and use of geospatial Open Data

    NASA Astrophysics Data System (ADS)

    Mazzetti, Paolo; Latre, Miguel; Kamali, Nargess; Brumana, Raffaella; Braumann, Stefan; Nativi, Stefano

    2016-04-01

    Open Data is a major trend in current information technology scenario and it is often publicised as one of the pillars of the information society in the near future. In particular, geospatial Open Data have a huge potential also for Earth Sciences, through the enablement of innovative applications and services integrating heterogeneous information. However, open does not mean usable. As it was recognized at the very beginning of the Web revolution, many different degrees of openness exist: from simple sharing in a proprietary format to advanced sharing in standard formats and including semantic information. Therefore, to fully unleash the potential of geospatial Open Data, advanced infrastructures are needed to increase the data openness degree, enhancing their usability. In October 2014, the ENERGIC OD (European NEtwork for Redistributing Geospatial Information to user Communities - Open Data) project, funded by the European Union under the Competitiveness and Innovation framework Programme (CIP), has started. In response to the EU call, the general objective of the project is to "facilitate the use of open (freely available) geographic data from different sources for the creation of innovative applications and services through the creation of Virtual Hubs". The ENERGIC OD Virtual Hubs aim to facilitate the use of geospatial Open Data by lowering and possibly removing the main barriers which hampers geo-information (GI) usage by end-users and application developers. Data and services heterogeneity is recognized as one of the major barriers to Open Data (re-)use. It imposes end-users and developers to spend a lot of effort in accessing different infrastructures and harmonizing datasets. Such heterogeneity cannot be completely removed through the adoption of standard specifications for service interfaces, metadata and data models, since different infrastructures adopt different standards to answer to specific challenges and to address specific use-cases. Thus, beyond a certain extent, heterogeneity is irreducible especially in interdisciplinary contexts. ENERGIC OD Virtual Hubs address heterogeneity adopting a mediation and brokering approach: specific components (brokers) are dedicated to harmonize service interfaces, metadata and data models, enabling seamless discovery and access to heterogeneous infrastructures and datasets. As an innovation project, ENERGIC OD integrates several existing technologies to implement Virtual Hubs as single points of access to geospatial datasets provided by new or existing platforms and infrastructures, including INSPIRE-compliant systems and Copernicus services. A first version of the ENERGIC OD brokers has been implemented based on the GI-Suite Brokering Framework developed by CNR-IIA, and complemented with other tools under integration and development. It already enables mediated discovery and harmonized access to different geospatial Open Data sources. It is accessible by users as Software-as-a-Service through a browser. Moreover, open APIs and a Javascript library are available for application developers. Six ENERGIC OD Virtual Hubs have been currently deployed: one at regional level (Berlin metropolitan area) and five at national-level (in France, Germany, Italy, Poland and Spain). Each Virtual Hub manager decided the deployment strategy (local infrastructure or commercial Infrastructure-as-a-Service cloud), and the list of connected Open Data sources. The ENERGIC OD Virtual Hubs are under test and validation through the development of ten different mobile and Web applications.

  5. Reproducibility of intraocular pressure peak and fluctuation of the water-drinking test.

    PubMed

    Hatanaka, Marcelo; Alencar, Luciana M; De Moraes, Carlos G; Susanna, Remo

    2013-01-01

    The water-drinking test has been used as a stress test to evaluate the drainage system of the eye. However, in order to be clinically applicable,a test must provide reproducible results with consistent measurements. This study was performed to verify the reproducibility of intraocular pressure peaks and fluctuation detected during the water-drinking test in patients with ocular hypertension and open-angle glaucoma. A prospective analysis of patients in a tertiary care unit for glaucoma treatment. Twenty-four ocular hypertension and 64 open-angle glaucoma patients not under treatment. The water-drinking test was performed in 2 consecutive days by the same examiners in patients not under treatment. Reproducibility was assessed using the intraclass correlation coefficient. Peak and fluctuation of intraocular pressure obtained with the water-drinking test were analysed for reproducibility. Eighty-eight eyes from 24 ocular hypertension and 64 open-angle glaucoma patients not under treatment were evaluated. Test and retest intraocular pressure peak values were 28.38 ± 4.64 and 28.38 ± 4.56 mmHg, respectively (P = 1.00). Test and retest intraocular pressure fluctuation values were 5.75 ± 3.9 and 4.99 ± 2.7 mmHg, respectively (P = 0.06). Based on intraclass coefficient, reproducibility was excellent for peak intraocular pressure (intraclass correlation coefficient = 0.79) and fair for intraocular pressure fluctuation (intraclass correlation coefficient = 0.37). Intraocular pressure peaks detected during the water-drinking test presented excellent reproducibility, whereas the reproducibility of fluctuation was considered fair. © 2012 The Authors. Clinical and Experimental Ophthalmology © 2012 Royal Australian and New Zealand College of Ophthalmologists.

  6. Emergency in-flight egress opening for general aviation aircraft. [pilot bailout

    NASA Technical Reports Server (NTRS)

    Bement, L. J.

    1980-01-01

    An emergency in-flight egress system was installed in a light general aviation airplane. The airplane had no provision for egress on the left side. To avoid a major structural redesign for a mechanical door, an add on 11.2 kg (24.6 lb) pyrotechnic-actuated system was developed to create an opening in the existing structure. The skin of the airplane was explosively severed around the side window, across a central stringer, and down to the floor, creating an opening of approximately 76 by 76 cm. The severed panel was jettisoned at an initial velocity of approximately 13.7 m/sec. System development included a total of 68 explosive severance tests on aluminum material using small samples, small and full scale flat panel aircraft structural mockups, and an actual aircraft fuselage. These tests proved explosive sizing/severance margins, explosive initiation, explosive product containment, and system dynamics. This technology is applicable to any aircraft of similar construction.

  7. 46 CFR 308.521 - Application for Open Cargo Policy, Form MA-301.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... Section 308.521 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.521 Application for Open Cargo Policy, Form MA-301. The standard form of application for a War Risk Open Cargo Policy...

  8. 46 CFR 308.506 - Application for an Open Cargo Policy.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Application for an Open Cargo Policy. 308.506 Section 308.506 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.506 Application for an Open...

  9. 46 CFR 308.521 - Application for Open Cargo Policy, Form MA-301.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... Section 308.521 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.521 Application for Open Cargo Policy, Form MA-301. The standard form of application for a War Risk Open Cargo Policy...

  10. 46 CFR 308.506 - Application for an Open Cargo Policy.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 46 Shipping 8 2013-10-01 2013-10-01 false Application for an Open Cargo Policy. 308.506 Section 308.506 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.506 Application for an Open...

  11. 46 CFR 308.521 - Application for Open Cargo Policy, Form MA-301.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... Section 308.521 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.521 Application for Open Cargo Policy, Form MA-301. The standard form of application for a War Risk Open Cargo Policy...

  12. 46 CFR 308.506 - Application for an Open Cargo Policy.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 46 Shipping 8 2011-10-01 2011-10-01 false Application for an Open Cargo Policy. 308.506 Section 308.506 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.506 Application for an Open...

  13. 46 CFR 308.521 - Application for Open Cargo Policy, Form MA-301.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... Section 308.521 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Open Policy War Risk Cargo Insurance § 308.521 Application for Open Cargo Policy, Form MA-301. The standard form of application for a War Risk Open Cargo Policy may...

  14. 46 CFR 308.506 - Application for an Open Cargo Policy.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 46 Shipping 8 2012-10-01 2012-10-01 false Application for an Open Cargo Policy. 308.506 Section 308.506 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.506 Application for an Open...

  15. 46 CFR 308.521 - Application for Open Cargo Policy, Form MA-301.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... Section 308.521 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance § 308.521 Application for Open Cargo Policy, Form MA-301. The standard form of application for a War Risk Open Cargo Policy...

  16. The image-guided surgery toolkit IGSTK: an open source C++ software toolkit.

    PubMed

    Enquobahrie, Andinet; Cheng, Patrick; Gary, Kevin; Ibanez, Luis; Gobbi, David; Lindseth, Frank; Yaniv, Ziv; Aylward, Stephen; Jomier, Julien; Cleary, Kevin

    2007-11-01

    This paper presents an overview of the image-guided surgery toolkit (IGSTK). IGSTK is an open source C++ software library that provides the basic components needed to develop image-guided surgery applications. It is intended for fast prototyping and development of image-guided surgery applications. The toolkit was developed through a collaboration between academic and industry partners. Because IGSTK was designed for safety-critical applications, the development team has adopted lightweight software processes that emphasizes safety and robustness while, at the same time, supporting geographically separated developers. A software process that is philosophically similar to agile software methods was adopted emphasizing iterative, incremental, and test-driven development principles. The guiding principle in the architecture design of IGSTK is patient safety. The IGSTK team implemented a component-based architecture and used state machine software design methodologies to improve the reliability and safety of the components. Every IGSTK component has a well-defined set of features that are governed by state machines. The state machine ensures that the component is always in a valid state and that all state transitions are valid and meaningful. Realizing that the continued success and viability of an open source toolkit depends on a strong user community, the IGSTK team is following several key strategies to build an active user community. These include maintaining a users and developers' mailing list, providing documentation (application programming interface reference document and book), presenting demonstration applications, and delivering tutorial sessions at relevant scientific conferences.

  17. An Ethnographic Case Study of the Administrative Organization, Processes, and Behavior in a Model Comprehensive High School.

    ERIC Educational Resources Information Center

    Zimman, Richard N.

    Using ethnographic case study methodology (involving open-ended interviews, participant observation, and document analysis) theories of administrative organization, processes, and behavior were tested during a three-week observation of a model comprehensive (experimental) high school. Although the study is limited in its general application, it…

  18. Peregrine Software Toolchains | High-Performance Computing | NREL

    Science.gov Websites

    toolchain is an open-source alternative against which many technical applications are natively developed and tested. The Portland Group compilers are not fully supported, but are available to the HPC community. Use Group (PGI) C/C++ and Fortran (partially supported) The PGI Accelerator compilers include NVIDIA GPU

  19. Real-Time Processing Library for Open-Source Hardware Biomedical Sensors

    PubMed Central

    Castro-García, Juan A.; Lebrato-Vázquez, Clara

    2018-01-01

    Applications involving data acquisition from sensors need samples at a preset frequency rate, the filtering out of noise and/or analysis of certain frequency components. We propose a novel software architecture based on open-software hardware platforms which allows programmers to create data streams from input channels and easily implement filters and frequency analysis objects. The performances of the different classes given in the size of memory allocated and execution time (number of clock cycles) were analyzed in the low-cost platform Arduino Genuino. In addition, 11 people took part in an experiment in which they had to implement several exercises and complete a usability test. Sampling rates under 250 Hz (typical for many biomedical applications) makes it feasible to implement filters, sliding windows and Fourier analysis, operating in real time. Participants rated software usability at 70.2 out of 100 and the ease of use when implementing several signal processing applications was rated at just over 4.4 out of 5. Participants showed their intention of using this software because it was percieved as useful and very easy to use. The performances of the library showed that it may be appropriate for implementing small biomedical real-time applications or for human movement monitoring, even in a simple open-source hardware device like Arduino Genuino. The general perception about this library is that it is easy to use and intuitive. PMID:29596394

  20. Real-Time Processing Library for Open-Source Hardware Biomedical Sensors.

    PubMed

    Molina-Cantero, Alberto J; Castro-García, Juan A; Lebrato-Vázquez, Clara; Gómez-González, Isabel M; Merino-Monge, Manuel

    2018-03-29

    Applications involving data acquisition from sensors need samples at a preset frequency rate, the filtering out of noise and/or analysis of certain frequency components. We propose a novel software architecture based on open-software hardware platforms which allows programmers to create data streams from input channels and easily implement filters and frequency analysis objects. The performances of the different classes given in the size of memory allocated and execution time (number of clock cycles) were analyzed in the low-cost platform Arduino Genuino. In addition, 11 people took part in an experiment in which they had to implement several exercises and complete a usability test. Sampling rates under 250 Hz (typical for many biomedical applications) makes it feasible to implement filters, sliding windows and Fourier analysis, operating in real time. Participants rated software usability at 70.2 out of 100 and the ease of use when implementing several signal processing applications was rated at just over 4.4 out of 5. Participants showed their intention of using this software because it was percieved as useful and very easy to use. The performances of the library showed that it may be appropriate for implementing small biomedical real-time applications or for human movement monitoring, even in a simple open-source hardware device like Arduino Genuino. The general perception about this library is that it is easy to use and intuitive.

  1. Open source database of images DEIMOS: extension for large-scale subjective image quality assessment

    NASA Astrophysics Data System (ADS)

    Vítek, Stanislav

    2014-09-01

    DEIMOS (Database of Images: Open Source) is an open-source database of images and video sequences for testing, verification and comparison of various image and/or video processing techniques such as compression, reconstruction and enhancement. This paper deals with extension of the database allowing performing large-scale web-based subjective image quality assessment. Extension implements both administrative and client interface. The proposed system is aimed mainly at mobile communication devices, taking into account advantages of HTML5 technology; it means that participants don't need to install any application and assessment could be performed using web browser. The assessment campaign administrator can select images from the large database and then apply rules defined by various test procedure recommendations. The standard test procedures may be fully customized and saved as a template. Alternatively the administrator can define a custom test, using images from the pool and other components, such as evaluating forms and ongoing questionnaires. Image sequence is delivered to the online client, e.g. smartphone or tablet, as a fully automated assessment sequence or viewer can decide on timing of the assessment if required. Environmental data and viewing conditions (e.g. illumination, vibrations, GPS coordinates, etc.), may be collected and subsequently analyzed.

  2. Design, Fabrication, and Performance of Foil Gas Thrust Bearings for Microturbomachinery Applications

    NASA Technical Reports Server (NTRS)

    Dykas, Brian; Bruckner, Robert; DellaCorte, Christopher; Edmonds, Brian; Prahl, Joseph

    2008-01-01

    A methodology for the design and construction of simple foil thrust bearings intended for parametric performance testing and low marginal costs is presented. Features drawn from a review of the open literature are discussed as they relate to bearing performance. The design of fixtures and tooling required to fabricate foil thrust bearings is presented, using conventional machining processes where possible. A prototype bearing with dimensions drawn from the literature is constructed, with all fabrication steps described. A load-deflection curve for the bearing is presented to illustrate structural stiffness characteristics. Start-top cycles are performed on the bearing at a temperature of 425 C to demonstrate early-life wear patterns. A test of bearing load capacity demonstrates useful performance when compared with data obtained from the open literature.

  3. A Generic Software Architecture For Prognostics

    NASA Technical Reports Server (NTRS)

    Teubert, Christopher; Daigle, Matthew J.; Sankararaman, Shankar; Goebel, Kai; Watkins, Jason

    2017-01-01

    Prognostics is a systems engineering discipline focused on predicting end-of-life of components and systems. As a relatively new and emerging technology, there are few fielded implementations of prognostics, due in part to practitioners perceiving a large hurdle in developing the models, algorithms, architecture, and integration pieces. As a result, no open software frameworks for applying prognostics currently exist. This paper introduces the Generic Software Architecture for Prognostics (GSAP), an open-source, cross-platform, object-oriented software framework and support library for creating prognostics applications. GSAP was designed to make prognostics more accessible and enable faster adoption and implementation by industry, by reducing the effort and investment required to develop, test, and deploy prognostics. This paper describes the requirements, design, and testing of GSAP. Additionally, a detailed case study involving battery prognostics demonstrates its use.

  4. A small, lightweight multipollutant sensor system for ground ...

    EPA Pesticide Factsheets

    Characterizing highly dynamic, transient, and vertically lofted emissions from open area sources poses unique measurement challenges. This study developed and applied a multipollutant sensor and integrated sampler system for use on mobile applications including tethered balloons (aerostats) and unmanned aerial vehicles (UAVs). The system is particularly applicable to open area sources, such as forest fires, due to its light weight (3.5 kg), compact size (6.75 L), and internal power supply. The sensor system, termed “Kolibri”, consists of sensors measuring CO2 and CO, and samplers for particulate matter (PM) and volatile organic compounds (VOCs). The Kolibri is controlled by a microcontroller which can record and transfer data in real time through a radio module. Selection of the sensors was based on laboratory testing for accuracy, response delay and recovery, cross-sensitivity, and precision. The Kolibri was compared against rack-mounted continuous emissions monitoring system (CEMs) and another mobile sampling instrument (the “Flyer”) that has been used in over ten open area pollutant sampling events. Our results showed that the time series of CO, CO2, and PM2.5 concentrations measured by the Kolibri agreed well with those from the CEMs and the Flyer, with a laboratory-tested percentage error of 4.9%, 3%, and 5.8%, respectively. The VOC emission factors obtained using the Kolibri were consistent with existing literature values that relate concentration

  5. Effect of ketamine on exploratory behaviour in BALB/C and C57BL/6 mice.

    PubMed

    Akillioglu, Kubra; Melik, Emine Babar; Melik, Enver; Boga, Ayper

    2012-01-01

    In this study, we evaluated the effect of ketamine on exploratory locomotion behaviours in the Balb/c and C57BL/6 strains of mice, which differ in their locomotion behaviours. Intraperitoneal administration of ketamine at three different doses (1, 5 or 10 mg/kg, 0.1 ml/10 gr body weight) was performed on adult male Balb/c and C57BL/6 mice. The same volume of saline was applied to the control group. The open-field and elevated plus maze apparatus were used to evaluate exploratory locomotion. In the open-field test, Balb/c mice less spend time in the centre of the field and was decreased locomotor activity compared to C57BL/6 mice (p<0.01). Ketamine treatment of Balb/c mice at 10 mg/kg dose caused an increase in locomotor activity and an increase in the amount of time spent in the centre in the open-field test, compared to the control group (p<0.05). In C57BL/6 mice, ketamine treatment (1 and 10 mg/kg) decreased locomotor activity (p<0.05). In C57BL/6 mice, the three different doses of ketamine application each caused a decrease in the frequency of centre crossing (p<0.001) and the spent time in the centre (p<0.05). In the elevated plus maze, the number of open-arm entries, the percentage of open-arm time and total arm entries were decreased in Balb/c mice compared to C57BL/6 mice (p<0.001). Ketamine treatment of Balb/c mice at 10 mg/kg dose caused an increase in the open-arm activity (p<0.001). Ketamine application (10 mg/kg) decreased the open-arm activity in C57BL/6 mice (p<0.05). A subanaesthetic dose of ketamine increased exploratory locomotion in Balb/c mice. In contrast, a subanaesthetic dose of ketamine decreased exploratory locomotion in C57BL/6 mice. In conclusion, hereditary factors may play an important role in ketamine-induced responses. Copyright © 2011 Elsevier Inc. All rights reserved.

  6. Evaluation of Carbon Nanotube Thin Films for Optically Transparent Microwave Applications Using On-Wafer Probing of Corbino Disc Test Structures

    DTIC Science & Technology

    2013-03-01

    the Material Under Test (MUT) against an open end of a coaxial cable . The novelty of our measurement scheme is the aspect of on-wafer probing. This...Directorate, ARL Julia B. Doggett George Washington University Henning Richter and Ramesh Sivarajan Nano -C, Inc...and Engineering Apprenticeship Program, George Washington University/Department of Defense, Washington, D.C., 20052 † Nano -C, Inc., 33 Southwest Park

  7. Extreme value analysis in biometrics.

    PubMed

    Hüsler, Jürg

    2009-04-01

    We review some approaches of extreme value analysis in the context of biometrical applications. The classical extreme value analysis is based on iid random variables. Two different general methods are applied, which will be discussed together with biometrical examples. Different estimation, testing, goodness-of-fit procedures for applications are discussed. Furthermore, some non-classical situations are considered where the data are possibly dependent, where a non-stationary behavior is observed in the data or where the observations are not univariate. A few open problems are also stated.

  8. Multilevel Parallelization of AutoDock 4.2.

    PubMed

    Norgan, Andrew P; Coffman, Paul K; Kocher, Jean-Pierre A; Katzmann, David J; Sosa, Carlos P

    2011-04-28

    Virtual (computational) screening is an increasingly important tool for drug discovery. AutoDock is a popular open-source application for performing molecular docking, the prediction of ligand-receptor interactions. AutoDock is a serial application, though several previous efforts have parallelized various aspects of the program. In this paper, we report on a multi-level parallelization of AutoDock 4.2 (mpAD4). Using MPI and OpenMP, AutoDock 4.2 was parallelized for use on MPI-enabled systems and to multithread the execution of individual docking jobs. In addition, code was implemented to reduce input/output (I/O) traffic by reusing grid maps at each node from docking to docking. Performance of mpAD4 was examined on two multiprocessor computers. Using MPI with OpenMP multithreading, mpAD4 scales with near linearity on the multiprocessor systems tested. In situations where I/O is limiting, reuse of grid maps reduces both system I/O and overall screening time. Multithreading of AutoDock's Lamarkian Genetic Algorithm with OpenMP increases the speed of execution of individual docking jobs, and when combined with MPI parallelization can significantly reduce the execution time of virtual screens. This work is significant in that mpAD4 speeds the execution of certain molecular docking workloads and allows the user to optimize the degree of system-level (MPI) and node-level (OpenMP) parallelization to best fit both workloads and computational resources.

  9. The construct of sexual openness for females in steady intimate relationships.

    PubMed

    Rausch, Diana; Dekker, Arne; Rettenberger, Martin

    2017-01-01

    The analysis of open-minded attitudes towards sexuality in general requires a construct based on attitudinal dimensions. Although several existing studies involve sexual attitudes, they differ substantially and standardized conceptual work is missing. Thus, the authors introduce the latent variable sexual openness to develop a construct based on self-oriented attitudes towards different sexual topics. Available survey data of female German students in a steady relationship allowed providing a first empirical test for the applicability of this construct. Five subdimensions are acknowledged central for sexual openness: sexual practices, masturbation, bisexuality, permissiveness, and pornography consumption. Confirmatory factor analysis and correlations confirmed the idea of an underlying mechanism with an impact on all five variables. Though further validation of the construct of sexual openness is required, the findings strongly support the notion of an overarching latent attitude variable, which influences the individual relation to everything sexual. The results were compared to other studies and potential approaches for future analyses were proposed.

  10. Space Subdivision in Indoor Mobile Laser Scanning Point Clouds Based on Scanline Analysis.

    PubMed

    Zheng, Yi; Peter, Michael; Zhong, Ruofei; Oude Elberink, Sander; Zhou, Quan

    2018-06-05

    Indoor space subdivision is an important aspect of scene analysis that provides essential information for many applications, such as indoor navigation and evacuation route planning. Until now, most proposed scene understanding algorithms have been based on whole point clouds, which has led to complicated operations, high computational loads and low processing speed. This paper presents novel methods to efficiently extract the location of openings (e.g., doors and windows) and to subdivide space by analyzing scanlines. An opening detection method is demonstrated that analyses the local geometric regularity in scanlines to refine the extracted opening. Moreover, a space subdivision method based on the extracted openings and the scanning system trajectory is described. Finally, the opening detection and space subdivision results are saved as point cloud labels which will be used for further investigations. The method has been tested on a real dataset collected by ZEB-REVO. The experimental results validate the completeness and correctness of the proposed method for different indoor environment and scanning paths.

  11. The construct of sexual openness for females in steady intimate relationships

    PubMed Central

    Rausch, Diana; Dekker, Arne; Rettenberger, Martin

    2017-01-01

    The analysis of open-minded attitudes towards sexuality in general requires a construct based on attitudinal dimensions. Although several existing studies involve sexual attitudes, they differ substantially and standardized conceptual work is missing. Thus, the authors introduce the latent variable sexual openness to develop a construct based on self-oriented attitudes towards different sexual topics. Available survey data of female German students in a steady relationship allowed providing a first empirical test for the applicability of this construct. Five subdimensions are acknowledged central for sexual openness: sexual practices, masturbation, bisexuality, permissiveness, and pornography consumption. Confirmatory factor analysis and correlations confirmed the idea of an underlying mechanism with an impact on all five variables. Though further validation of the construct of sexual openness is required, the findings strongly support the notion of an overarching latent attitude variable, which influences the individual relation to everything sexual. The results were compared to other studies and potential approaches for future analyses were proposed. PMID:28636608

  12. A Spanish matrix sentence test for assessing speech reception thresholds in noise.

    PubMed

    Hochmuth, Sabine; Brand, Thomas; Zokoll, Melanie A; Castro, Franz Zenker; Wardenga, Nina; Kollmeier, Birger

    2012-07-01

    To develop, optimize, and evaluate a new Spanish sentence test in noise. The test comprises a basic matrix of ten names, verbs, numerals, nouns, and adjectives. From this matrix, test lists of ten sentences with an equal syntactical structure can be formed at random, with each list containing the whole speech material. The speech material represents the phoneme distribution of the Spanish language. The test was optimized for measuring speech reception thresholds (SRTs) in noise by adjusting the presentation levels of the individual words. Subsequently, the test was evaluated by independent measurements investigating the training effects, the comparability of test lists, open-set vs. closed-set test format, and performance of listeners of different Spanish varieties. In total, 68 normal-hearing native Spanish-speaking listeners. SRTs measured using an adaptive procedure were 6.2 ± 0.8 dB SNR for the open-set and 7.2 ± 0.7 dB SNR for the closed-set test format. The residual training effect was less than 1 dB after using two double-lists before data collection. No significant differences were found for listeners of different Spanish varieties indicating that the test is applicable to Spanish as well as Latin American listeners. Test lists can be used interchangeably.

  13. SSIART: Opening the Way to Wireless Sensor Networks On-Board Spacecraft with an Inter-Agency Research Environment

    NASA Astrophysics Data System (ADS)

    Gunes-Lasnet, Sev; Dufour, Jean-Francois

    2012-08-01

    The potential uses and benefits of wireless technologies in space are very broad. Since many years the CCSDS SOIS wireless working group has worked at the identification of key applications for which wireless would bring benefits, and at supporting the deployment of wireless in space thanks to documents, in particular a Green informative book and magenta books presenting recommended practices.The Smart Sensor Inter-Agency Research Test bench (SSIART) is being designed to provide the space Agencies and the Industry with a reference smart sensor platform to test wireless sensor technologies in reference representative applications and RF propagation environments, while promoting these technologies at the same time.

  14. Primary stability of an intramedullary calcaneal nail and an angular stable calcaneal plate in a biomechanical testing model of intraarticular calcaneal fracture.

    PubMed

    Goldzak, M; Simon, P; Mittlmeier, T; Chaussemier, M; Chiergatti, R

    2014-01-01

    Nowadays, open anatomic reduction and internal fixation can be considered as a valuable treatment for displaced intra-articular fractures of the calcaneus. However, the application of a calcaneal plate via an extensile lateral approach is at risk for a substantial rate of complications including delayed healing, skin necrosis, or infection. There is some evidence that a limited exposure might contribute to a decreased soft tissue complication rate bearing in mind that most minimally invasive techniques have to accept a reduced primary stability compared with the open application of an angular stable plate. Recently, an intrafocal minimal invasive reduction technique has been established employing an intramedullary nail for fracture stabilisation and support of the subtalar joint. The aim of this study was to compare the primary biomechanical performance of the new device versus lateral angular stable plating. Biomechanical testings were performed on 14 human cadaveric feet (7 pairs). Dry calcaneal bones were fractured resulting in a Sanders type IIB fracture pattern and fixed by either a calcaneal locking plate or an intramedullary calcaneal nail. Compressive testing via the corresponding talus was employed at a constant loading velocity until failure with an universal testing machine and a specific mounting device to avoid any shear forces. Apart from the data of the load deformation diagram the relative motion of the fracture elements during loading was recorded by 8 extensometric transducers. After failure the specimens were carefully examined to check the failure patterns. The displacement of the subtalar joint fragment was substantially lower in specimens fixed with the nail. Stiffness and load to failure were significantly higher after fixation with the intramedullary nail than after application of the angular stable plate. Failure with both fixation modes generally occurred at the anterior calcaneal process fragment. The primary stability of an intramedullary nail appeared to be superior to an angular stable plate representing the present standard technique in open reconstruction of the fractured calcaneus. The results from the experimental model speak in favour of the clinical use of the intramedullary calcaneal nail. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. SU-G-BRB-02: An Open-Source Software Analysis Library for Linear Accelerator Quality Assurance

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kerns, J; Yaldo, D

    Purpose: Routine linac quality assurance (QA) tests have become complex enough to require automation of most test analyses. A new data analysis software library was built that allows physicists to automate routine linear accelerator quality assurance tests. The package is open source, code tested, and benchmarked. Methods: Images and data were generated on a TrueBeam linac for the following routine QA tests: VMAT, starshot, CBCT, machine logs, Winston Lutz, and picket fence. The analysis library was built using the general programming language Python. Each test was analyzed with the library algorithms and compared to manual measurements taken at the timemore » of acquisition. Results: VMAT QA results agreed within 0.1% between the library and manual measurements. Machine logs (dynalogs & trajectory logs) were successfully parsed; mechanical axis positions were verified for accuracy and MLC fluence agreed well with EPID measurements. CBCT QA measurements were within 10 HU and 0.2mm where applicable. Winston Lutz isocenter size measurements were within 0.2mm of TrueBeam’s Machine Performance Check. Starshot analysis was within 0.2mm of the Winston Lutz results for the same conditions. Picket fence images with and without a known error showed that the library was capable of detecting MLC offsets within 0.02mm. Conclusion: A new routine QA software library has been benchmarked and is available for use by the community. The library is open-source and extensible for use in larger systems.« less

  16. Mobile service for open data visualization on geo-based images

    NASA Astrophysics Data System (ADS)

    Lee, Kiwon; Kim, Kwangseob; Kang, Sanggoo

    2015-12-01

    Since the early 2010s, governments in most countries have adopted and promoted open data policy and open data platform. Korea are in the same situation, and government and public organizations have operated the public-accessible open data portal systems since 2011. The number of open data and data type have been increasing every year. These trends are more expandable or extensible on mobile environments. The purpose of this study is to design and implement a mobile application service to visualize various typed or formatted public open data with geo-based images on the mobile web. Open data cover downloadable data sets or open-accessible data application programming interface API. Geo-based images mean multi-sensor satellite imageries which are referred in geo-coordinates and matched with digital map sets. System components for mobile service are fully based on open sources and open development environments without any commercialized tools: PostgreSQL for database management system, OTB for remote sensing image processing, GDAL for data conversion, GeoServer for application server, OpenLayers for mobile web mapping, R for data analysis and D3.js for web-based data graphic processing. Mobile application in client side was implemented by using HTML5 for cross browser and cross platform. The result shows many advantageous points such as linking open data and geo-based data, integrating open data and open source, and demonstrating mobile applications with open data. It is expected that this approach is cost effective and process efficient implementation strategy for intelligent earth observing data.

  17. Bayesian Atmospheric Radiative Transfer (BART)Thermochemical Equilibrium Abundance (TEA) Code and Application to WASP-43b

    NASA Astrophysics Data System (ADS)

    Blecic, Jasmina; Harrington, Joseph; Bowman, Matthew O.; Cubillos, Patricio E.; Stemm, Madison; Foster, Andrew

    2014-11-01

    We present a new, open-source, Thermochemical Equilibrium Abundances (TEA) code that calculates the abundances of gaseous molecular species. TEA uses the Gibbs-free-energy minimization method with an iterative Lagrangian optimization scheme. It initializes the radiative-transfer calculation in our Bayesian Atmospheric Radiative Transfer (BART) code. Given elemental abundances, TEA calculates molecular abundances for a particular temperature and pressure or a list of temperature-pressure pairs. The code is tested against the original method developed by White at al. (1958), the analytic method developed by Burrows and Sharp (1999), and the Newton-Raphson method implemented in the open-source Chemical Equilibrium with Applications (CEA) code. TEA is written in Python and is available to the community via the open-source development site GitHub.com. We also present BART applied to eclipse depths of WASP-43b exoplanet, constraining atmospheric thermal and chemical parameters. This work was supported by NASA Planetary Atmospheres grant NNX12AI69G and NASA Astrophysics Data Analysis Program grant NNX13AF38G. JB holds a NASA Earth and Space Science Fellowship.

  18. An informatics model for guiding assembly of telemicrobiology workstations for malaria collaborative diagnostics using commodity products and open-source software.

    PubMed

    Suhanic, West; Crandall, Ian; Pennefather, Peter

    2009-07-17

    Deficits in clinical microbiology infrastructure exacerbate global infectious disease burdens. This paper examines how commodity computation, communication, and measurement products combined with open-source analysis and communication applications can be incorporated into laboratory medicine microbiology protocols. Those commodity components are all now sourceable globally. An informatics model is presented for guiding the use of low-cost commodity components and free software in the assembly of clinically useful and usable telemicrobiology workstations. The model incorporates two general principles: 1) collaborative diagnostics, where free and open communication and networking applications are used to link distributed collaborators for reciprocal assistance in organizing and interpreting digital diagnostic data; and 2) commodity engineering, which leverages globally available consumer electronics and open-source informatics applications, to build generic open systems that measure needed information in ways substantially equivalent to more complex proprietary systems. Routine microscopic examination of Giemsa and fluorescently stained blood smears for diagnosing malaria is used as an example to validate the model. The model is used as a constraint-based guide for the design, assembly, and testing of a functioning, open, and commoditized telemicroscopy system that supports distributed acquisition, exploration, analysis, interpretation, and reporting of digital microscopy images of stained malarial blood smears while also supporting remote diagnostic tracking, quality assessment and diagnostic process development. The open telemicroscopy workstation design and use-process described here can address clinical microbiology infrastructure deficits in an economically sound and sustainable manner. It can boost capacity to deal with comprehensive measurement of disease and care outcomes in individuals and groups in a distributed and collaborative fashion. The workstation enables local control over the creation and use of diagnostic data, while allowing for remote collaborative support of diagnostic data interpretation and tracking. It can enable global pooling of malaria disease information and the development of open, participatory, and adaptable laboratory medicine practices. The informatic model highlights how the larger issue of access to generic commoditized measurement, information processing, and communication technology in both high- and low-income countries can enable diagnostic services that are much less expensive, but substantially equivalent to those currently in use in high-income countries.

  19. Application Period Open for NCI Biospecimen Use | Division of Cancer Prevention

    Cancer.gov

    The application period for investigators interested in obtaining biospecimens and data from the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial re-opened June 1. A separate application for obtaining biospecimens and data with research funding is also open. |

  20. The multilingual matrix test: Principles, applications, and comparison across languages: A review.

    PubMed

    Kollmeier, Birger; Warzybok, Anna; Hochmuth, Sabine; Zokoll, Melanie A; Uslar, Verena; Brand, Thomas; Wagener, Kirsten C

    2015-01-01

    A review of the development, evaluation, and application of the so-called 'matrix sentence test' for speech intelligibility testing in a multilingual society is provided. The format allows for repeated use with the same patient in her or his native language even if the experimenter does not understand the language. Using a closed-set format, the syntactically fixed, semantically unpredictable sentences (e.g. 'Peter bought eight white ships') provide a vocabulary of 50 words (10 alternatives for each position in the sentence). The principles (i.e. construction, optimization, evaluation, and validation) for 14 different languages are reviewed. Studies of the influence of talker, language, noise, the training effect, open vs. closed conduct of the test, and the subjects' language proficiency are reported and application examples are discussed. The optimization principles result in a steep intelligibility function and a high homogeneity of the speech materials presented and test lists employed, yielding a high efficiency and excellent comparability across languages. The characteristics of speakers generally dominate the differences across languages. The matrix test format with the principles outlined here is recommended for producing efficient, reliable, and comparable speech reception thresholds across different languages.

  1. The Long-Term Safety of S-Flurbiprofen Plaster for Osteoarthritis Patients: An Open-Label, 52-Week Study.

    PubMed

    Yataba, Ikuko; Otsuka, Noboru; Matsushita, Isao; Matsumoto, Hideo; Hoshino, Yuichi

    2016-08-01

    The newly developed S-flurbiprofen plaster (SFPP) is a tape-type patch that shows innovative percutaneous absorption. This study was designed to evaluate the safety of a long-term 52-week SFPP application to osteoarthritis (OA) patients. This was a multi-center, open-label, uncontrolled prospective study that included 201 OA patients. SFPP at 40 mg/day was applied to the site of pain in 101 patients and at 80 mg/day (2 patches) in 100 patients at a total of 301 sites for 52 weeks. The affected sites assessed included the knee (192), lumbar spine (66), cervical spine (26), and others (17). Drug safety was evaluated by medical examination, laboratory tests, and examination of vital signs. Efficacy was evaluated by the patient's and clinician's global assessments and clinical symptoms. Most patients (80.1 %) completed the 52-week SFPP application. The majority of drug-related adverse events (AEs) included mild dermatitis at the application sites and occurred in 46.8 % of the sites. No photosensitive dermatitis was observed. Systemic AEs occurred in 9.0 % of the patients; a serious AE (gastric ulcer hemorrhage) occurred in one patient. No clinically significant changes in the laboratory tests and vital signs were observed. The efficacy evaluation showed an improvement from 2 weeks after the SFPP application, which continued during the 52 weeks' treatment. No apparent safety concerns were observed, even during the long-term SFPP application. Therefore, SFPP could be an additional pharmacotherapy in OA treatment.

  2. A Kind of Optimization Method of Loading Documents in OpenOffice.org

    NASA Astrophysics Data System (ADS)

    Lan, Yuqing; Li, Li; Zhou, Wenbin

    As a giant in open source community, OpenOffice.org has become the most popular office suite within Linux community. But OpenOffice.org is relatively slow while loading documents. Research shows that the most time consuming part is importing one page of whole document. If there are many pages in a document, the accumulation of time consumed can be astonishing. Therefore, this paper proposes a solution, which has improved the speed of loading documents through asynchronous importing mechanism: a document is not imported as a whole, but only part of the document is imported at first for display, then mechanism in the background is started to asynchronously import the remaining parts, and insert it into the drawing queue of OpenOffice.org for display. In this way, the problem can be solved and users don't have to wait for a long time. Application start-up time testing tool has been used to test the time consumed in loading different pages of documents before and after optimization of OpenOffice.org, then, we adopt the regression theory to analyse the correlation between the page number of documents and the loading time. In addition, visual modeling of the experimental data are acquired with the aid of matlab. An obvious increase in loading speed can be seen after a comparison of the time consumed to load a document before and after the solution is adopted. And then, using Microsoft Office compared with the optimized OpenOffice.org, their loading speeds are almost same. The results of the experiments show the effectiveness of this solution.

  3. Rotor systems research aircraft simulation mathematical model

    NASA Technical Reports Server (NTRS)

    Houck, J. A.; Moore, F. L.; Howlett, J. J.; Pollock, K. S.; Browne, M. M.

    1977-01-01

    An analytical model developed for evaluating and verifying advanced rotor concepts is discussed. The model was used during in both open loop and real time man-in-the-loop simulation during the rotor systems research aircraft design. Future applications include: pilot training, preflight of test programs, and the evaluation of promising concepts before their implementation on the flight vehicle.

  4. I've Gathered a Basket of Communication and Collaboration Tools

    ERIC Educational Resources Information Center

    Chang, May

    2004-01-01

    In this article, the author, a Web development librarian at North Carolina State University (NCSU) Libraries, recounts how she initiated the implementation of a series of open source communication and collaboration applications for the Libraries' Web site and intranet, and how she gathered a number of tried and tested C&C tools that can…

  5. 77 FR 16990 - Notification of Submission to the Secretary of Agriculture of Two Draft Regulatory Documents...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-03-23

    ... and Applicability; Clarification and Availability of Test Guideline''; and the second is entitled... Yard (South Bldg.), 2777 S. Crystal Dr., Arlington, VA. The Docket Facility is open from 8:30 a.m. to 4...) 305-5805. FOR FURTHER INFORMATION CONTACT: Rose Kyprianou, Field and External Affairs Division (7506P...

  6. 78 FR 20315 - Columbia Gas Transmission, LLC; Notice of Request under Blanket Authorization

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-04-04

    ... Coco C Storage Fields in West Virginia. Columbia states that, as a result of storage field tests, the overall capacity of these fields can be increased. Columbia does not propose to expand the boundaries... fields, all as more fully set forth in the application, which is on file with the Commission and open to...

  7. 4onse: four times open & non-conventional technology for sensing the environment

    NASA Astrophysics Data System (ADS)

    Cannata, Massimiliano; Ratnayake, Rangageewa; Antonovic, Milan; Strigaro, Daniele; Cardoso, Mirko; Hoffmann, Marcus

    2017-04-01

    The availability of complete, quality and dense monitoring hydro-meteorological data is essential to address a number of practical issues including, but not limited to, flood-water and urban drainage management, climate change impact assessment, early warning and risk management, now-casting and weather predictions. Thanks to the recent technological advances such as Internet Of Things, Big Data and Ubiquitous Internet, non-conventional monitoring systems based on open technologies and low cost sensors may represent a great opportunity either as a complement of authoritative monitoring network or as a vital source of information wherever existing monitoring networks are in decline or completely missing. Nevertheless, scientific literature on such a kind of open and non-conventional monitoring systems is still limited and often relates to prototype engineering and testing in rather limited case studies. For this reason the 4onse project aims at integrating existing open technologies in the field of Free & Open Source Software, Open Hardware, Open Data, and Open Standards and evaluate this kind of system in a real case (about 30 stations) for a medium period of 2 years to better scientifically understand strengths, criticalities and applicabilities in terms of data quality; system durability; management costs; performances; sustainability. The ultimate objective is to contribute in non-conventional monitoring systems adoption based on four open technologies.

  8. The effects of Transcutaneous Electrical Nerve Stimulation on postural control in patients with chronic low back pain.

    PubMed

    Rojhani-Shirazi, Z; Rezaeian, T

    2015-01-01

    Objective: The effects of transcutaneous electrical nerve stimulation (TENS) on postural control in patients with low back pain which is not well known. This study aimed to evaluate the effects of TENS on postural control in chronic low back pain. Methods: This study was an experimental research design. Twenty-eight patients with chronic LBP (25-45 Y/ O) participated and by using a random allocation, were divided to samples who participated in this study. The mean center of pressure (COP) velocity and displacement were measured before, immediately and 30 min after the intervention. The tests were done with eyes open and closed on a force platform. Sensory electrical stimulation was applied through the TENS device. The descriptive statistics, independent sample T-test and ANOVA with repeated measurement on time were used for data analysis. Results: The results of the present study demonstrated that the application of the sensory electrical stimulation in chronic LBP patients showed a statistically significant improvement in postural control in Medio-lateral direction with no corresponding effect on the anterior-posterior direction immediately following the TENS application and 30 minutes after it in closed eyes conditions as compared to baseline. The application of TENS decreased the displacement and velocity of COP (p≤0.05), 30 minutes after the application of sensory electrical stimulation. The results showed that the mean displacement and velocity of COP decreased in eyes open position (p≤0.05). Also, immediately and 30 minutes after the application of sensory electrical stimulation, COP displacement and velocity in ML direction with eyes closed significantly decreased in the intervention group in comparison with control group (p≤0.05). Conclusion: The application of TENS in patients with chronic low back pain could improve postural control in these patients.

  9. The effects of Transcutaneous Electrical Nerve Stimulation on postural control in patients with chronic low back pain

    PubMed Central

    Rojhani-Shirazi, Z; Rezaeian, T

    2015-01-01

    Objective: The effects of transcutaneous electrical nerve stimulation (TENS) on postural control in patients with low back pain which is not well known. This study aimed to evaluate the effects of TENS on postural control in chronic low back pain. Methods: This study was an experimental research design. Twenty-eight patients with chronic LBP (25-45 Y/ O) participated and by using a random allocation, were divided to samples who participated in this study. The mean center of pressure (COP) velocity and displacement were measured before, immediately and 30 min after the intervention. The tests were done with eyes open and closed on a force platform. Sensory electrical stimulation was applied through the TENS device. The descriptive statistics, independent sample T-test and ANOVA with repeated measurement on time were used for data analysis. Results: The results of the present study demonstrated that the application of the sensory electrical stimulation in chronic LBP patients showed a statistically significant improvement in postural control in Medio-lateral direction with no corresponding effect on the anterior-posterior direction immediately following the TENS application and 30 minutes after it in closed eyes conditions as compared to baseline. The application of TENS decreased the displacement and velocity of COP (p≤0.05), 30 minutes after the application of sensory electrical stimulation. The results showed that the mean displacement and velocity of COP decreased in eyes open position (p≤0.05). Also, immediately and 30 minutes after the application of sensory electrical stimulation, COP displacement and velocity in ML direction with eyes closed significantly decreased in the intervention group in comparison with control group (p≤0.05). Conclusion: The application of TENS in patients with chronic low back pain could improve postural control in these patients. PMID:28255392

  10. Agricultural and Management Practices and Bacterial Contamination in Greenhouse versus Open Field Lettuce Production

    PubMed Central

    Holvoet, Kevin; Sampers, Imca; Seynnaeve, Marleen; Jacxsens, Liesbeth; Uyttendaele, Mieke

    2014-01-01

    The aim of this study was to gain insight into potential differences in risk factors for microbial contamination in greenhouse versus open field lettuce production. Information was collected on sources, testing, and monitoring and if applicable, treatment of irrigation and harvest rinsing water. These data were combined with results of analysis on the levels of Escherichia coli as a fecal indicator organism and the presence of enteric bacterial pathogens on both lettuce crops and environmental samples. Enterohemorragic Escherichia coli (EHEC) PCR signals (vt1 or vt2 positive and eae positive), Campylobacter spp., and Salmonella spp. isolates were more often obtained from irrigation water sampled from open field farms (21/45, 46.7%) versus from greenhouse production (9/75, 12.0%). The open field production was shown to be more prone to fecal contamination as the number of lettuce samples and irrigation water with elevated E. coli was significantly higher. Farmers comply with generic guidelines on good agricultural practices available at the national level, but monitoring of microbial quality, and if applicable appropriateness of water treatment, or water used for irrigation or at harvest is restricted. These results indicate the need for further elaboration of specific guidelines and control measures for leafy greens with regard to microbial hazards. PMID:25546272

  11. Agricultural and management practices and bacterial contamination in greenhouse versus open field lettuce production.

    PubMed

    Holvoet, Kevin; Sampers, Imca; Seynnaeve, Marleen; Jacxsens, Liesbeth; Uyttendaele, Mieke

    2014-12-23

    The aim of this study was to gain insight into potential differences in risk factors for microbial contamination in greenhouse versus open field lettuce production. Information was collected on sources, testing, and monitoring and if applicable, treatment of irrigation and harvest rinsing water. These data were combined with results of analysis on the levels of Escherichia coli as a fecal indicator organism and the presence of enteric bacterial pathogens on both lettuce crops and environmental samples. Enterohemorragic Escherichia coli (EHEC) PCR signals (vt1 or vt2 positive and eae positive), Campylobacter spp., and Salmonella spp. isolates were more often obtained from irrigation water sampled from open field farms (21/45, 46.7%) versus from greenhouse production (9/75, 12.0%). The open field production was shown to be more prone to fecal contamination as the number of lettuce samples and irrigation water with elevated E. coli was significantly higher. Farmers comply with generic guidelines on good agricultural practices available at the national level, but monitoring of microbial quality, and if applicable appropriateness of water treatment, or water used for irrigation or at harvest is restricted. These results indicate the need for further elaboration of specific guidelines and control measures for leafy greens with regard to microbial hazards.

  12. Suspicious Behavior Detection System for an Open Space Parking Based on Recognition of Human Elemental Actions

    NASA Astrophysics Data System (ADS)

    Inomata, Teppei; Kimura, Kouji; Hagiwara, Masafumi

    Studies for video surveillance applications for preventing various crimes such as stealing and violence have become a hot topic. This paper proposes a new video surveillance system that can detect suspicious behaviors such as a car break-in and vandalization in an open space parking, and that is based on image processing. The proposed system has the following features: it 1)deals time series data flow, 2)recognizes “human elemental actions” using statistic features, and 3)detects suspicious behavior using Subspace method and AdaBoost. We conducted the experiments to test the performance of the proposed system using open space parking scenes. As a result, we obtained about 10.0% for false positive rate, and about 4.6% for false negative rate.

  13. Chemical sensors for breath gas analysis: the latest developments at the Breath Analysis Summit 2013.

    PubMed

    Tisch, Ulrike; Haick, Hossam

    2014-06-01

    Profiling the body chemistry by means of volatile organic compounds (VOCs) in the breath opens exciting new avenues in medical diagnostics. Gas sensors could provide ideal platforms for realizing portable, hand-held breath testing devices in the near future. This review summarizes the latest developments and applications in the field of chemical sensors for diagnostic breath testing that were presented at the Breath Analysis Summit 2013 in Wallerfangen, Germany. Considerable progress has been made towards clinically applicable breath testing devices, especially by utilizing chemo-sensitive nanomaterials. Examples of several specialized breath testing applications are presented that are either based on stand-alone nanomaterial-based sensors being highly sensitive and specific to individual breath compounds over others, or on combinations of several highly specific sensors, or on experimental nanomaterial-based sensors arrays. Other interesting approaches include the adaption of a commercially available MOx-based sensor array to indirect breath testing applications, using a sample pre-concentration method, and the development of compact integrated GC-sensor systems. The recent trend towards device integration has led to the development of fully integrated prototypes of point-of-care devices. We describe and compare the performance of several prototypes that are based on different sensing technologies and evaluate their potential as low-cost and readily available next-generation medical devices.

  14. The SAMI2 Open Source Project

    NASA Astrophysics Data System (ADS)

    Huba, J. D.; Joyce, G.

    2001-05-01

    In the past decade, the Open Source Model for software development has gained popularity and has had numerous major achievements: emacs, Linux, the Gimp, and Python, to name a few. The basic idea is to provide the source code of the model or application, a tutorial on its use, and a feedback mechanism with the community so that the model can be tested, improved, and archived. Given the success of the Open Source Model, we believe it may prove valuable in the development of scientific research codes. With this in mind, we are `Open Sourcing' the low to mid-latitude ionospheric model that has recently been developed at the Naval Research Laboratory: SAMI2 (Sami2 is Another Model of the Ionosphere). The model is comprehensive and uses modern numerical techniques. The structure and design of SAMI2 make it relatively easy to understand and modify: the numerical algorithms are simple and direct, and the code is reasonably well-written. Furthermore, SAMI2 is designed to run on personal computers; prohibitive computational resources are not necessary, thereby making the model accessible and usable by virtually all researchers. For these reasons, SAMI2 is an excellent candidate to explore and test the open source modeling paradigm in space physics research. We will discuss various topics associated with this project. Research supported by the Office of Naval Research.

  15. The effect of project-based learning on students' statistical literacy levels for data representation

    NASA Astrophysics Data System (ADS)

    Koparan, Timur; Güven, Bülent

    2015-07-01

    The point of this study is to define the effect of project-based learning approach on 8th Grade secondary-school students' statistical literacy levels for data representation. To achieve this goal, a test which consists of 12 open-ended questions in accordance with the views of experts was developed. Seventy 8th grade secondary-school students, 35 in the experimental group and 35 in the control group, took this test twice, one before the application and one after the application. All the raw scores were turned into linear points by using the Winsteps 3.72 modelling program that makes the Rasch analysis and t-tests, and an ANCOVA analysis was carried out with the linear points. Depending on the findings, it was concluded that the project-based learning approach increases students' level of statistical literacy for data representation. Students' levels of statistical literacy before and after the application were shown through the obtained person-item maps.

  16. A Relationship Between Constraint and the Critical Crack Tip Opening Angle

    NASA Technical Reports Server (NTRS)

    Johnston, William M.; James, Mark A.

    2009-01-01

    Of the various approaches used to model and predict fracture, the Crack Tip Opening Angle (CTOA) fracture criterion has been successfully used for a wide range of two-dimensional thin-sheet and thin plate applications. As thicker structure is considered, modeling the full three-dimensional fracture process will become essential. This paper investigates relationships between the local CTOA evaluated along a three-dimensional crack front and the corresponding local constraint. Previously reported tunneling crack front shapes were measured during fracture by pausing each test and fatigue cycling the specimens to mark the crack surface. Finite element analyses were run to model the tunneling shape during fracture, with the analysis loading conditions duplicating those tests. The results show an inverse relationship between the critical fracture value and constraint which is valid both before maximum load and after maximum load.

  17. PaaS for web applications with OpenShift Origin

    NASA Astrophysics Data System (ADS)

    Lossent, A.; Rodriguez Peon, A.; Wagner, A.

    2017-10-01

    The CERN Web Frameworks team has deployed OpenShift Origin to facilitate deployment of web applications and to improving efficiency in terms of computing resource usage. OpenShift leverages Docker containers and Kubernetes orchestration to provide a Platform-as-a-service solution oriented for web applications. We will review use cases and how OpenShift was integrated with other services such as source control, web site management and authentication services.

  18. Duke Surgery Patient Safety: an open-source application for anonymous reporting of adverse and near-miss surgical events

    PubMed Central

    Pietrobon, Ricardo; Lima, Raquel; Shah, Anand; Jacobs, Danny O; Harker, Matthew; McCready, Mariana; Martins, Henrique; Richardson, William

    2007-01-01

    Background Studies have shown that 4% of hospitalized patients suffer from an adverse event caused by the medical treatment administered. Some institutions have created systems to encourage medical workers to report these adverse events. However, these systems often prove to be inadequate and/or ineffective for reviewing the data collected and improving the outcomes in patient safety. Objective To describe the Web-application Duke Surgery Patient Safety, designed for the anonymous reporting of adverse and near-miss events as well as scheduled reporting to surgeons and hospital administration. Software architecture DSPS was developed primarily using Java language running on a Tomcat server and with MySQL database as its backend. Results Formal and field usability tests were used to aid in development of DSPS. Extensive experience with DSPS at our institution indicate that DSPS is easy to learn and use, has good speed, provides needed functionality, and is well received by both adverse-event reporters and administrators. Discussion This is the first description of an open-source application for reporting patient safety, which allows the distribution of the application to other institutions in addition for its ability to adapt to the needs of different departments. DSPS provides a mechanism for anonymous reporting of adverse events and helps to administer Patient Safety initiatives. Conclusion The modifiable framework of DSPS allows adherence to evolving national data standards. The open-source design of DSPS permits surgical departments with existing reporting mechanisms to integrate them with DSPS. The DSPS application is distributed under the GNU General Public License. PMID:17472749

  19. Duke Surgery Patient Safety: an open-source application for anonymous reporting of adverse and near-miss surgical events.

    PubMed

    Pietrobon, Ricardo; Lima, Raquel; Shah, Anand; Jacobs, Danny O; Harker, Matthew; McCready, Mariana; Martins, Henrique; Richardson, William

    2007-05-01

    Studies have shown that 4% of hospitalized patients suffer from an adverse event caused by the medical treatment administered. Some institutions have created systems to encourage medical workers to report these adverse events. However, these systems often prove to be inadequate and/or ineffective for reviewing the data collected and improving the outcomes in patient safety. To describe the Web-application Duke Surgery Patient Safety, designed for the anonymous reporting of adverse and near-miss events as well as scheduled reporting to surgeons and hospital administration. SOFTWARE ARCHITECTURE: DSPS was developed primarily using Java language running on a Tomcat server and with MySQL database as its backend. Formal and field usability tests were used to aid in development of DSPS. Extensive experience with DSPS at our institution indicate that DSPS is easy to learn and use, has good speed, provides needed functionality, and is well received by both adverse-event reporters and administrators. This is the first description of an open-source application for reporting patient safety, which allows the distribution of the application to other institutions in addition for its ability to adapt to the needs of different departments. DSPS provides a mechanism for anonymous reporting of adverse events and helps to administer Patient Safety initiatives. The modifiable framework of DSPS allows adherence to evolving national data standards. The open-source design of DSPS permits surgical departments with existing reporting mechanisms to integrate them with DSPS. The DSPS application is distributed under the GNU General Public License.

  20. Occupational protein contact dermatitis in food handlers.

    PubMed

    Hjorth, N; Roed-Petersen, J

    1976-02-01

    The preparation of food in restaurant kitchens carries a high risk of occupational dermatoses. Analysis of 33 cases revealed four different etiological types. Simple irritant dermatitis was rare (2 cases), plain contact dermatitis was more common (6 cases). Fifteen patients had relevant patch tests and scratch tests; ten had positive scratch tests only to explain the cause of their dermatitis. The last type was termed protein contact dermatitis. The major type IV allergens incriminated were metals, onion and garlic. The major proteinaceous allergens indicated by history and test results were fish and shell-fish. Open patch tests with the incriminated foods may cause erythema or oedema on normal skin after 20 minutes. Previously eczematous, now normal looking, skin often responds with a crop of dyshidrotic vesicles preceded by erythema and itching 30 minutes after the application of an open test. Examination for specific IgE is not always positive in such cases. Inhalant allergy was rare. The results indicate that food handlers are sensitized by the protein they touch, and then react to later contact with the proteins. Protein contact dermatitis is similarly common among veterinary surgeons, while the importance in other occupational groups remains to be studied.

  1. Research on OpenStack of open source cloud computing in colleges and universities’ computer room

    NASA Astrophysics Data System (ADS)

    Wang, Lei; Zhang, Dandan

    2017-06-01

    In recent years, the cloud computing technology has a rapid development, especially open source cloud computing. Open source cloud computing has attracted a large number of user groups by the advantages of open source and low cost, have now become a large-scale promotion and application. In this paper, firstly we briefly introduced the main functions and architecture of the open source cloud computing OpenStack tools, and then discussed deeply the core problems of computer labs in colleges and universities. Combining with this research, it is not that the specific application and deployment of university computer rooms with OpenStack tool. The experimental results show that the application of OpenStack tool can efficiently and conveniently deploy cloud of university computer room, and its performance is stable and the functional value is good.

  2. A study on single lane-change manoeuvres for determining rearward amplification of multi-trailer articulated heavy vehicles with active trailer steering systems

    NASA Astrophysics Data System (ADS)

    Wang, Qiushi; He, Yuping

    2016-01-01

    The Society of Automotive Engineers issued a test procedure, SAE-J2179, to determine the rearward amplification (RA) of multi-trailer articulated heavy vehicles (MTAHVs). Built upon the procedure, the International Organization for Standardization released the test manoeuvres, ISO-14791, for evaluating directional performance of MTAHVs. For the RA measures, ISO-14791 recommends two single lane-change manoeuvres: (1) an open-loop procedure with a single sine-wave steering input; and (2) a closed-loop manoeuvre with a single sine-wave lateral acceleration input. For an articulated vehicle with active trailer steering (ATS), the RA measure in lateral acceleration under the open-loop manoeuvre was not in good agreement with that under the closed-loop manoeuvre. This observation motivates the research on the applicability of the two manoeuvres for the RA measures of MTAHVs with ATS. It is reported that transient response under the open-loop manoeuvre often leads to asymmetric curve of tractor lateral acceleration [Winkler CB, Fancher PS, Bareket Z, Bogard S, Johnson G, Karamihas S, Mink C. Heavy vehicle size and weight - test procedures for minimum safety performance standards. Final technical report, NHTSA, US DOT, contract DTNH22-87-D-17174, University of Michigan Transportation Research Institute, Report No. UMTRI-92-13; 1992]. To explore the effect of the transient response, a multiple cycle sine-wave steering input (MCSSI) manoeuvre is proposed. Simulation demonstrates that the steady-state RA measures of an MTAHV with and without ATS under the MCSSI manoeuvre are in excellent agreement with those under the closed-loop manoeuvre. It is indicated that between the two manoeuvres by ISO-14791, the closed-loop manoeuvre is more applicable for determining the RA measures of MTAHVs with ATS.

  3. Open data models for smart health interconnected applications: the example of openEHR.

    PubMed

    Demski, Hans; Garde, Sebastian; Hildebrand, Claudia

    2016-10-22

    Smart Health is known as a concept that enhances networking, intelligent data processing and combining patient data with other parameters. Open data models can play an important role in creating a framework for providing interoperable data services that support the development of innovative Smart Health applications profiting from data fusion and sharing. This article describes a model-driven engineering approach based on standardized clinical information models and explores its application for the development of interoperable electronic health record systems. The following possible model-driven procedures were considered: provision of data schemes for data exchange, automated generation of artefacts for application development and native platforms that directly execute the models. The applicability of the approach in practice was examined using the openEHR framework as an example. A comprehensive infrastructure for model-driven engineering of electronic health records is presented using the example of the openEHR framework. It is shown that data schema definitions to be used in common practice software development processes can be derived from domain models. The capabilities for automatic creation of implementation artefacts (e.g., data entry forms) are demonstrated. Complementary programming libraries and frameworks that foster the use of open data models are introduced. Several compatible health data platforms are listed. They provide standard based interfaces for interconnecting with further applications. Open data models help build a framework for interoperable data services that support the development of innovative Smart Health applications. Related tools for model-driven application development foster semantic interoperability and interconnected innovative applications.

  4. Profugus

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Evans, Thomas; Hamilton, Steven; Slattery, Stuart

    Profugus is an open-source mini-application (mini-app) for radiation transport and reactor applications. It contains the fundamental computational kernels used in the Exnihilo code suite from Oak Ridge National Laboratory. However, Exnihilo is production code with a substantial user base. Furthermore, Exnihilo is export controlled. This makes collaboration with computer scientists and computer engineers difficult. Profugus is designed to bridge that gap. By encapsulating the core numerical algorithms in an abbreviated code base that is open-source, computer scientists can analyze the algorithms and easily make code-architectural changes to test performance without compromising the production code values of Exnihilo. Profugus is notmore » meant to be production software with respect to problem analysis. The computational kernels in Profugus are designed to analyze performance, not correctness. Nonetheless, users of Profugus can setup and run problems with enough real-world features to be useful as proof-of-concept for actual production work.« less

  5. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Krishnamurthy, Dheepak

    This paper is an overview of Power System Simulation Toolbox (psst). psst is an open-source Python application for the simulation and analysis of power system models. psst simulates the wholesale market operation by solving a DC Optimal Power Flow (DCOPF), Security Constrained Unit Commitment (SCUC) and a Security Constrained Economic Dispatch (SCED). psst also includes models for the various entities in a power system such as Generator Companies (GenCos), Load Serving Entities (LSEs) and an Independent System Operator (ISO). psst features an open modular object oriented architecture that will make it useful for researchers to customize, expand, experiment beyond solvingmore » traditional problems. psst also includes a web based Graphical User Interface (GUI) that allows for user friendly interaction and for implementation on remote High Performance Computing (HPCs) clusters for parallelized operations. This paper also provides an illustrative application of psst and benchmarks with standard IEEE test cases to show the advanced features and the performance of toolbox.« less

  6. A baroclinic quasigeostrophic open ocean model

    NASA Technical Reports Server (NTRS)

    Miller, R. N.; Robinson, A. R.; Haidvogel, D. B.

    1983-01-01

    A baroclinic quasigeostrophic open ocean model is presented, calibrated by a series of test problems, and demonstrated to be feasible and efficient for application to realistic mid-oceanic mesoscale eddy flow regimes. Two methods of treating the depth dependence of the flow, a finite difference method and a collocation method, are tested and intercompared. Sample Rossby wave calculations with and without advection are performed with constant stratification and two levels of nonlinearity, one weaker than and one typical of real ocean flows. Using exact analytical solutions for comparison, the accuracy and efficiency of the model is tabulated as a function of the computational parameters and stability limits set; typically, errors were controlled between 1 percent and 10 percent RMS after two wave periods. Further Rossby wave tests with realistic stratification and wave parameters chosen to mimic real ocean conditions were performed to determine computational parameters for use with real and simulated data. Finally, a prototype calculation with quasiturbulent simulated data was performed successfully, which demonstrates the practicality of the model for scientific use.

  7. Silicon quantum dots for energetic material applications

    NASA Astrophysics Data System (ADS)

    Adams, Sarah K.; Piekiel, Nicholas W.; Ervin, Matthew H.; Morris, Christopher J.

    2018-06-01

    In its history as an energetic material, porous silicon has demonstrated flame speeds in excess of 3 km s-1, tunable combustion behavior, and high energy output, which in theory makes it a very attractive energetic system. In practice, its application within the field is limited by porous silicon's typical substrate-adhered form and caustic chemical processing requirements that limit how and when porous silicon is made. In this work, we have relieved porous silicon of these constraints by creating reactive silicon quantum dots from free-standing porous silicon films. The resulting material is composed of crystalline silicon nanoparticles with diameters as small as 2 nm that retain the chemical properties of the original films including the SiH2 termination layer. The fabricated silicon particles were characterized using FTIR Spectroscopy, TEM, and EDS for determining the size and the chemical composition. For testing as an energetic material fuel, porous silicon was mixed with an oft used oxidizer, sodium perchlorate. During open-channel combustion tests, silicon quantum dots mixed with sodium perchlorate demonstrated flame speeds over 2.5 km s-1, while bomb calorimetry tests showed an average heat of combustion of 7.4 kJ g-1. These results demonstrate the ability to retain the porous silicon material properties that allow for highly energetic material reactions to occur, despite the additional processing steps to create silicon quantum dots. This opens the door for the use of porous silicon in the bulk of the energetic material application space, much of which was previously limited due to the substrate-attached nature of typical porous silicon.

  8. Laparoscopic versus open liver segmentectomy: prospective, case-matched, intention-to-treat analysis of clinical outcomes and cost effectiveness.

    PubMed

    Polignano, Francesco M; Quyn, Aaron J; de Figueiredo, Rodrigo S M; Henderson, Nikola A; Kulli, Christoph; Tait, Iain S

    2008-12-01

    Reduction in hospital stay, blood loss, postoperative pain and complications are common findings after laparoscopic liver resection, suggesting that the laparoscopic approach may be a suitable alternative to open surgery. Some concerns have been raised regarding cost effectiveness of this procedure and potential implications of its large-scale application. Our aim has been to determine cost effectiveness of laparoscopic liver surgery by a case-matched, case-control, intention-to-treat analysis of its costs and short-term clinical outcomes compared with open surgery. Laparoscopic liver segmentectomies and bisegmentectomies performed at Ninewells Hospital and Medical School between 2005 and 2007 were considered. Resections involving more than two Couinaud segments, or involving any synchronous procedure, were excluded. An operation-magnitude-matched control group was identified amongst open liver resections performed between 2004 and 2007. Hospital costs were obtained from the Scottish Health Service Costs Book (ISD Scotland) and average national costs were calculated. Cost of theatre time, disposable surgical devices, hospital stay, and high-dependency unit (HDU) and intensive care unit (ICU) usage were the main endpoints for comparison. Secondary endpoints were morbidity and mortality. Statistical analysis was performed with Student's t-test, chi(2) and Fisher exact test as most appropriate. Twenty-five laparoscopic liver resections were considered, including atypical resection, segmentectomy and bisegmentectomy, and they were compared to 25 matching open resections. The two groups were homogeneous by age, sex, coexistent morbidity, magnitude of resection, prevalence of liver cirrhosis and indications. Operative time (p < 0.03), blood loss (p < 0.0001), Pringle manoeuvre (p < 0.03), hospital stay (p < 0.003) and postoperative complications (p < 0.002) were significantly reduced in the laparoscopic group. Overall hospital cost was significantly lower in the laparoscopic group by an average of 2,571 pounds sterling (p < 0.04). Laparoscopic liver segmentectomy and bisegmentectomy are feasible, safe and cost effective compared to similar open resections. Large-scale application of laparoscopic liver surgery could translate into significant savings to hospitals and health care programmes.

  9. VideoHacking: Automated Tracking and Quantification of Locomotor Behavior with Open Source Software and Off-the-Shelf Video Equipment.

    PubMed

    Conklin, Emily E; Lee, Kathyann L; Schlabach, Sadie A; Woods, Ian G

    2015-01-01

    Differences in nervous system function can result in differences in behavioral output. Measurements of animal locomotion enable the quantification of these differences. Automated tracking of animal movement is less labor-intensive and bias-prone than direct observation, and allows for simultaneous analysis of multiple animals, high spatial and temporal resolution, and data collection over extended periods of time. Here, we present a new video-tracking system built on Python-based software that is free, open source, and cross-platform, and that can analyze video input from widely available video capture devices such as smartphone cameras and webcams. We validated this software through four tests on a variety of animal species, including larval and adult zebrafish (Danio rerio), Siberian dwarf hamsters (Phodopus sungorus), and wild birds. These tests highlight the capacity of our software for long-term data acquisition, parallel analysis of multiple animals, and application to animal species of different sizes and movement patterns. We applied the software to an analysis of the effects of ethanol on thigmotaxis (wall-hugging) behavior on adult zebrafish, and found that acute ethanol treatment decreased thigmotaxis behaviors without affecting overall amounts of motion. The open source nature of our software enables flexibility, customization, and scalability in behavioral analyses. Moreover, our system presents a free alternative to commercial video-tracking systems and is thus broadly applicable to a wide variety of educational settings and research programs.

  10. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lopez, Jesse E.; Baptista, António M.

    A sediment model coupled to the hydrodynamic model SELFE is validated against a benchmark combining a set of idealized tests and an application to a field-data rich energetic estuary. After sensitivity studies, model results for the idealized tests largely agree with previously reported results from other models in addition to analytical, semi-analytical, or laboratory results. Results of suspended sediment in an open channel test with fixed bottom are sensitive to turbulence closure and treatment for hydrodynamic bottom boundary. Results for the migration of a trench are very sensitive to critical stress and erosion rate, but largely insensitive to turbulence closure.more » The model is able to qualitatively represent sediment dynamics associated with estuarine turbidity maxima in an idealized estuary. Applied to the Columbia River estuary, the model qualitatively captures sediment dynamics observed by fixed stations and shipborne profiles. Representation of the vertical structure of suspended sediment degrades when stratification is underpredicted. Across all tests, skill metrics of suspended sediments lag those of hydrodynamics even when qualitatively representing dynamics. The benchmark is fully documented in an openly available repository to encourage unambiguous comparisons against other models.« less

  11. Integrating Symbolic and Statistical Methods for Testing Intelligent Systems Applications to Machine Learning and Computer Vision

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jha, Sumit Kumar; Pullum, Laura L; Ramanathan, Arvind

    Embedded intelligent systems ranging from tiny im- plantable biomedical devices to large swarms of autonomous un- manned aerial systems are becoming pervasive in our daily lives. While we depend on the flawless functioning of such intelligent systems, and often take their behavioral correctness and safety for granted, it is notoriously difficult to generate test cases that expose subtle errors in the implementations of machine learning algorithms. Hence, the validation of intelligent systems is usually achieved by studying their behavior on representative data sets, using methods such as cross-validation and bootstrapping.In this paper, we present a new testing methodology for studyingmore » the correctness of intelligent systems. Our approach uses symbolic decision procedures coupled with statistical hypothesis testing to. We also use our algorithm to analyze the robustness of a human detection algorithm built using the OpenCV open-source computer vision library. We show that the human detection implementation can fail to detect humans in perturbed video frames even when the perturbations are so small that the corresponding frames look identical to the naked eye.« less

  12. Space Telecommunications Radio System (STRS) Compliance Testing

    NASA Technical Reports Server (NTRS)

    Handler, Louis M.

    2011-01-01

    The Space Telecommunications Radio System (STRS) defines an open architecture for software defined radios. This document describes the testing methodology to aid in determining the degree of compliance to the STRS architecture. Non-compliances are reported to the software and hardware developers as well as the NASA project manager so that any non-compliances may be fixed or waivers issued. Since the software developers may be divided into those that provide the operating environment including the operating system and STRS infrastructure (OE) and those that supply the waveform applications, the tests are divided accordingly. The static tests are also divided by the availability of an automated tool that determines whether the source code and configuration files contain the appropriate items. Thus, there are six separate step-by-step test procedures described as well as the corresponding requirements that they test. The six types of STRS compliance tests are: STRS application automated testing, STRS infrastructure automated testing, STRS infrastructure testing by compiling WFCCN with the infrastructure, STRS configuration file testing, STRS application manual code testing, and STRS infrastructure manual code testing. Examples of the input and output of the scripts are shown in the appendices as well as more specific information about what to configure and test in WFCCN for non-compliance. In addition, each STRS requirement is listed and the type of testing briefly described. Attached is also a set of guidelines on what to look for in addition to the requirements to aid in the document review process.

  13. Demonstration of Supervisory Control and Data Acquisition (SCADA) Virtualization Capability in the US Army Research Laboratory (ARL)/Sustaining Base Network Assurance Branch (SBNAB) US Army Cyber Analytics Laboratory (ACAL) SCADA Hardware Testbed

    DTIC Science & Technology

    2015-05-01

    application ,1 while the simulated PLC software is the open source ModbusPal Java application . When queried using the Modbus TCP protocol, ModbusPal reports...and programmable logic controller ( PLC ) components. The HMI and PLC components were instantiated with software and installed in multiple virtual...creating and capturing HMI– PLC network traffic over a 24-h period in the virtualized network and inspect the packets for errors.  Test the

  14. Havery Mudd 2014-2015 Computer Science Conduit Clinic Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Aspesi, G; Bai, J; Deese, R

    2015-05-12

    Conduit, a new open-source library developed at Lawrence Livermore National Laboratories, provides a C++ application programming interface (API) to describe and access scientific data. Conduit’s primary use is for inmemory data exchange in high performance computing (HPC) applications. Our team tested and improved Conduit to make it more appealing to potential adopters in the HPC community. We extended Conduit’s capabilities by prototyping four libraries: one for parallel communication using MPI, one for I/O functionality, one for aggregating performance data, and one for data visualization.

  15. Step-control of electromechanical systems

    DOEpatents

    Lewis, Robert N.

    1979-01-01

    The response of an automatic control system to a general input signal is improved by applying a test input signal, observing the response to the test input signal and determining correctional constants necessary to provide a modified input signal to be added to the input to the system. A method is disclosed for determining correctional constants. The modified input signal, when applied in conjunction with an operating signal, provides a total system output exhibiting an improved response. This method is applicable to open-loop or closed-loop control systems. The method is also applicable to unstable systems, thus allowing controlled shut-down before dangerous or destructive response is achieved and to systems whose characteristics vary with time, thus resulting in improved adaptive systems.

  16. Development of multi-ampered D{sup {minus}} source for fusion applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jacquot, C.; Belchenko, Y.; Bucalossi, J.

    1996-07-01

    Large current and high current density deuterium negative ion sources are investigated on the MANTIS test bed with the objective of producing several amperes of D{sup {minus}} beams, at an accelerated current density in the range 10{endash}20 mA/cm{sup 2}, for possible application in future neutral beam injectors, e.g. ITER. As a first step, the DRAGON source, which was built by Culham Laboratory was tested on the MANTIS test bed in order to test this large source using only {open_quote}{open_quote}pure volume{close_quote}{close_quote} production of negative ions. The accelerated negative ion current is found to be a strong function of the source operatingmore » pressure and the arc power, and a significant isotopic effect is observed. The maximum accelerated currents are 1.3 A of H{sup {minus}} (3.3 mA/cm{sup 2}) and 0.5 A (1.3 mA/cm{sup 2}) at 110 kW of arc power. Cesium injection from a non conventional dispenser together with an improved extraction system, have significantly improved the D-current. A maximum of 14 mA/cm{sup 2} of D{sup {minus}1} are accelerated at 30 kV, which corresponds potentially, to more than 5 A for a full aperture extraction with an arc power of 140 kW (2250 A of arc current). {copyright} {ital 1996 American Institute of Physics.}« less

  17. Performance Portability Strategies for Grid C++ Expression Templates

    NASA Astrophysics Data System (ADS)

    Boyle, Peter A.; Clark, M. A.; DeTar, Carleton; Lin, Meifeng; Rana, Verinder; Vaquero Avilés-Casco, Alejandro

    2018-03-01

    One of the key requirements for the Lattice QCD Application Development as part of the US Exascale Computing Project is performance portability across multiple architectures. Using the Grid C++ expression template as a starting point, we report on the progress made with regards to the Grid GPU offloading strategies. We present both the successes and issues encountered in using CUDA, OpenACC and Just-In-Time compilation. Experimentation and performance on GPUs with a SU(3)×SU(3) streaming test will be reported. We will also report on the challenges of using current OpenMP 4.x for GPU offloading in the same code.

  18. Relation between inflammables and ignition sources in aircraft environments

    NASA Technical Reports Server (NTRS)

    Scull, Wilfred E

    1951-01-01

    A literature survey was conducted to determine the relation between aircraft ignition sources and inflammables. Available literature applicable to the problem of aircraft fire hazards is analyzed and discussed. Data pertaining to the effect of many variables on ignition temperatures, minimum ignition pressures, minimum spark-ignition energies of inflammables, quenching distances of electrode configurations, and size of openings through which flame will not propagate are presented and discussed. Ignition temperatures and limits of inflammability of gasoline in air in different test environments, and the minimum ignition pressures and minimum size of opening for flame propagation in gasoline-air mixtures are included; inerting of gasoline-air mixtures is discussed.

  19. Development of an open metadata schema for prospective clinical research (openPCR) in China.

    PubMed

    Xu, W; Guan, Z; Sun, J; Wang, Z; Geng, Y

    2014-01-01

    In China, deployment of electronic data capture (EDC) and clinical data management system (CDMS) for clinical research (CR) is in its very early stage, and about 90% of clinical studies collected and submitted clinical data manually. This work aims to build an open metadata schema for Prospective Clinical Research (openPCR) in China based on openEHR archetypes, in order to help Chinese researchers easily create specific data entry templates for registration, study design and clinical data collection. Singapore Framework for Dublin Core Application Profiles (DCAP) is used to develop openPCR and four steps such as defining the core functional requirements and deducing the core metadata items, developing archetype models, defining metadata terms and creating archetype records, and finally developing implementation syntax are followed. The core functional requirements are divided into three categories: requirements for research registration, requirements for trial design, and requirements for case report form (CRF). 74 metadata items are identified and their Chinese authority names are created. The minimum metadata set of openPCR includes 3 documents, 6 sections, 26 top level data groups, 32 lower data groups and 74 data elements. The top level container in openPCR is composed of public document, internal document and clinical document archetypes. A hierarchical structure of openPCR is established according to Data Structure of Electronic Health Record Architecture and Data Standard of China (Chinese EHR Standard). Metadata attributes are grouped into six parts: identification, definition, representation, relation, usage guides, and administration. OpenPCR is an open metadata schema based on research registration standards, standards of the Clinical Data Interchange Standards Consortium (CDISC) and Chinese healthcare related standards, and is to be publicly available throughout China. It considers future integration of EHR and CR by adopting data structure and data terms in Chinese EHR Standard. Archetypes in openPCR are modularity models and can be separated, recombined, and reused. The authors recommend that the method to develop openPCR can be referenced by other countries when designing metadata schema of clinical research. In the next steps, openPCR should be used in a number of CR projects to test its applicability and to continuously improve its coverage. Besides, metadata schema for research protocol can be developed to structurize and standardize protocol, and syntactical interoperability of openPCR with other related standards can be considered.

  20. Air-Powered Projectile Launcher

    NASA Technical Reports Server (NTRS)

    Andrews, T.; Bjorklund, R. A.; Elliott, D. G.; Jones, L. K.

    1987-01-01

    Air-powered launcher fires plastic projectiles without using explosive propellants. Does not generate high temperatures. Launcher developed for combat training for U.S. Army. With reservoir pressurized, air launcher ready to fire. When pilot valve opened, sleeve (main valve) moves to rear. Projectile rapidly propelled through barrel, pushed by air from reservoir. Potential applications in seismic measurements, avalanche control, and testing impact resistance of windshields on vehicles.

  1. Effect of Porosity Content of Arc-Sprayed Alloy 625 Skins on the Flexural Behavior of Nickel Foam Core Sandwich Structures

    NASA Astrophysics Data System (ADS)

    Salavati, S.; Pershin, L.; Coyle, T. W.; Mostaghimi, J.

    2015-01-01

    Metallic foam core sandwich structures have been of particular interest for engineering applications in recent decades because of their unique mechanical and physical properties. Thermal spraying techniques have been recently introduced as a novel low-cost method for production of these structures with complex shapes. One of the potential applications of the metallic foam core sandwich structures prepared by thermal spray techniques is as heat shield devices. Open porosity in the microstructure of the coating may allow the cooling efficiency of the heat shield to be improved through the film cooling phenomenon. A modified twin wire-arc spraying process was employed to deposit high temperature resistant alloy 625 coatings with a high percentage of the open porosity. The effect of skin porosity on the mechanical properties (flexural rigidity) of the sandwich structures was studied using a four-point bending test. It was concluded from the four-point bending test results that increase in the porosity content of the coatings leads to decrease in the flexural rigidity of the sandwich panels. The ductility of the porous and conventional arc-sprayed alloy 625 coatings was improved after heat treatment at 1100 °C for 3 h.

  2. Planetary Radio Interferometry and Doppler Experiment (PRIDE) technique: A test case of the Mars Express Phobos Flyby. II. Doppler tracking: Formulation of observed and computed values, and noise budget

    NASA Astrophysics Data System (ADS)

    Bocanegra-Bahamón, T. M.; Molera Calvés, G.; Gurvits, L. I.; Duev, D. A.; Pogrebenko, S. V.; Cimò, G.; Dirkx, D.; Rosenblatt, P.

    2018-01-01

    Context. Closed-loop Doppler data obtained by deep space tracking networks, such as the NASA Deep Space Network (DSN) and the ESA tracking station network (Estrack), are routinely used for navigation and science applications. By shadow tracking the spacecraft signal, Earth-based radio telescopes involved in the Planetary Radio Interferometry and Doppler Experiment (PRIDE) can provide open-loop Doppler tracking data only when the dedicated deep space tracking facilities are operating in closed-loop mode. Aims: We explain the data processing pipeline in detail and discuss the capabilities of the technique and its potential applications in planetary science. Methods: We provide the formulation of the observed and computed values of the Doppler data in PRIDE tracking of spacecraft and demonstrate the quality of the results using an experiment with the ESA Mars Express spacecraft as a test case. Results: We find that the Doppler residuals and the corresponding noise budget of the open-loop Doppler detections obtained with the PRIDE stations compare to the closed-loop Doppler detections obtained with dedicated deep space tracking facilities.

  3. Free and open-source automated 3-D microscope.

    PubMed

    Wijnen, Bas; Petersen, Emily E; Hunt, Emily J; Pearce, Joshua M

    2016-11-01

    Open-source technology not only has facilitated the expansion of the greater research community, but by lowering costs it has encouraged innovation and customizable design. The field of automated microscopy has continued to be a challenge in accessibility due the expense and inflexible, noninterchangeable stages. This paper presents a low-cost, open-source microscope 3-D stage. A RepRap 3-D printer was converted to an optical microscope equipped with a customized, 3-D printed holder for a USB microscope. Precision measurements were determined to have an average error of 10 μm at the maximum speed and 27 μm at the minimum recorded speed. Accuracy tests yielded an error of 0.15%. The machine is a true 3-D stage and thus able to operate with USB microscopes or conventional desktop microscopes. It is larger than all commercial alternatives, and is thus capable of high-depth images over unprecedented areas and complex geometries. The repeatability is below 2-D microscope stages, but testing shows that it is adequate for the majority of scientific applications. The open-source microscope stage costs less than 3-9% of the closest proprietary commercial stages. This extreme affordability vastly improves accessibility for 3-D microscopy throughout the world. © 2016 The Authors Journal of Microscopy © 2016 Royal Microscopical Society.

  4. Development of a thermally-assisted piercing (TAP) process for introducing holes into thermoplastic composites

    NASA Astrophysics Data System (ADS)

    Brown, Nicholas W. A.

    Composite parts can be manufactured to near-net shape with minimum wastage of material; however, there is almost always a need for further machining. The most common post-manufacture machining operations for composite materials are to create holes for assembly. This thesis presents and discusses a thermally-assisted piercing process that can be used as a technique for introducing holes into thermoplastic composites. The thermally-assisted piercing process heats up, and locally melts, thermoplastic composites to allow material to be displaced around a hole, rather than cutting them out from the structure. This investigation was concerned with how the variation of piercing process parameters (such as the size of the heated area, the temperature of the laminate prior to piercing and the geometry of the piercing spike) changed the material microstructure within carbon fibre/Polyetheretherketone (PEEK) laminates. The variation of process parameters was found to significantly affect the formation of resin rich regions, voids and the fibre volume fraction in the material surrounding the hole. Mechanical testing (using open-hole tension, open-hole compression, plain-pin bearing and bolted bearing tests) showed that the microstructural features created during piercing were having significant influence over the resulting mechanical performance of specimens. By optimising the process parameters strength improvements of up to 11% and 21% were found for pierced specimens when compared with drilled specimens for open-hole tension and compression loading, respectively. For plain-pin and bolted bearing tests, maximum strengths of 77% and 85%, respectively, were achieved when compared with drilled holes. Improvements in first failure force (by 10%) and the stress at 4% hole elongation (by 18%), however, were measured for the bolted bearing tests when compared to drilled specimens. The overall performance of pierced specimens in an industrially relevant application ultimately depends on the properties required for that specific scenario. The results within this thesis show that the piercing technique could be used as a direct replacement to drilling depending on this application.

  5. Tank Information System (tis): a Case Study in Migrating Web Mapping Application from Flex to Dojo for Arcgis Server and then to Open Source

    NASA Astrophysics Data System (ADS)

    Pulsani, B. R.

    2017-11-01

    Tank Information System is a web application which provides comprehensive information about minor irrigation tanks of Telangana State. As part of the program, a web mapping application using Flex and ArcGIS server was developed to make the data available to the public. In course of time as Flex be-came outdated, a migration of the client interface to the latest JavaScript based technologies was carried out. Initially, the Flex based application was migrated to ArcGIS JavaScript API using Dojo Toolkit. Both the client applications used published services from ArcGIS server. To check the migration pattern from proprietary to open source, the JavaScript based ArcGIS application was later migrated to OpenLayers and Dojo Toolkit which used published service from GeoServer. The migration pattern noticed in the study especially emphasizes upon the use of Dojo Toolkit and PostgreSQL database for ArcGIS server so that migration to open source could be performed effortlessly. The current ap-plication provides a case in study which could assist organizations in migrating their proprietary based ArcGIS web applications to open source. Furthermore, the study reveals cost benefits of adopting open source against commercial software's.

  6. Anaesthetic modulation of nicotinic ion channel kinetics in bovine chromaffin cells.

    PubMed Central

    Charlesworth, P; Richards, C D

    1995-01-01

    1. We have investigated the action of the anaesthetics methoxyflurane, methohexitone and etomidate on the nicotinic acetylcholine receptor channel of bovine adrenal chromaffin cells using the whole cell patch clamp technique. 2. Spectral analysis of macroscopic currents evoked by 25 microM carbachol revealed that each of the agents tested reduced the lifetime of the channel open state in a dose-dependent manner. The whole cell current was inhibited in a concentration-dependent fashion by each agent. 3. Channel gating parameters were calculated from single channel studies and the results used to test models explaining the modulation of nicotinic acetylcholine receptor channels by anaesthetics. 4. Each of the agents studied reduced the mean channel open time in a concentration-dependent manner. Anaesthetic concentrations reducing mean open time by 50% were: 370 microM methoxyflurane, 30 microM methohexitone or 23 microM etomidate. 5. Methohexitone and etomidate produced an increase in the number of brief closures within bursts, while no such increase was observed with methoxyflurane. Despite these inter-burst gaps, mean burst length was reduced by each of the agents tested. 6. It is concluded that a simple sequential blocking model fails to account for the action of these anaesthetics. An extended model, in which blocked channels can close, may be applicable. PMID:7773553

  7. IAEA international studies on irradiation embrittlement of reactor pressure vessel steels

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brumovsky, M.; Steele, L.E.

    1997-02-01

    In last 25 years, three phases a Co-operative Research Programme on Irradiation Embrittlement of Reactor Pressure Vessel Steels has been organized by the International Atomic Energy Agency. This programme started with eight countries in 1971 and finally 16 countries took part in phase III of the Programme in 1983. Several main efforts were put into preparation of the programme, but the principal task was concentrated on an international comparison of radiation damage characterization by different laboratories for steels of {open_quotes}old{close_quotes} (with high impurity contents) and {open_quotes}advanced{close_quotes} (with low impurity contents) types as well as on development of small scale fracturemore » mechanics procedures applicable to reactor pressure vessel surveillance programmes. This year, a new programme has been opened, concentrated mostly on small scale fracture mechanics testing.« less

  8. Porosity Assessment for Different Diameters of Coir Lignocellulosic Fibers

    NASA Astrophysics Data System (ADS)

    da Luz, Fernanda Santos; Paciornik, Sidnei; Monteiro, Sergio Neves; da Silva, Luiz Carlos; Tommasini, Flávio James; Candido, Verônica Scarpini

    2017-10-01

    The application of natural lignocellulosic fibers (LCFs) in engineering composites has increased interest in their properties and structural characteristics. In particular, the inherent porosity of an LCF markedly affects its density and the adhesion to polymer matrices. For the first time, both open and closed porosities of a natural LCF, for different diameter ranges, were assessed. Fibers extracted from the mesocarp of the coconut fruit were investigated by nondestructive methods of density measurements and x-ray microtomography (microCT). It was found that, for all diameter ranges, the closed porosity is significantly higher than the open porosity. The total porosity increases with diameter to around 60% for coir fibers with more than 503 μm in diameter. The amount and characteristics of these open and closed porosities were revealed by t test and Weibull statistics as well as by microCT.

  9. Field portable low temperature porous layer open tubular cryoadsorption headspace sampling and analysis part II: Applications.

    PubMed

    Harries, Megan; Bukovsky-Reyes, Santiago; Bruno, Thomas J

    2016-01-15

    This paper details the sampling methods used with the field portable porous layer open tubular cryoadsorption (PLOT-cryo) approach, described in Part I of this two-part series, applied to several analytes of interest. We conducted tests with coumarin and 2,4,6-trinitrotoluene (two solutes that were used in initial development of PLOT-cryo technology), naphthalene, aviation turbine kerosene, and diesel fuel, on a variety of matrices and test beds. We demonstrated that these analytes can be easily detected and reliably identified using the portable unit for analyte collection. By leveraging efficiency-boosting temperature control and the high flow rate multiple capillary wafer, very short collection times (as low as 3s) yielded accurate detection. For diesel fuel spiked on glass beads, we determined a method detection limit below 1 ppm. We observed greater variability among separate samples analyzed with the portable unit than previously documented in work using the laboratory-based PLOT-cryo technology. We identify three likely sources that may help explain the additional variation: the use of a compressed air source to generate suction, matrix geometry, and variability in the local vapor concentration around the sampling probe as solute depletion occurs both locally around the probe and in the test bed as a whole. This field-portable adaptation of the PLOT-cryo approach has numerous and diverse potential applications. Published by Elsevier B.V.

  10. Field Portable Low Temperature Porous Layer Open Tubular Cryoadsorption Headspace Sampling and Analysis Part II: Applications*

    PubMed Central

    Harries, Megan; Bukovsky-Reyes, Santiago; Bruno, Thomas J.

    2016-01-01

    This paper details the sampling methods used with the field portable porous layer open tubular cryoadsorption (PLOT-cryo) approach, described in Part I of this two-part series, applied to several analytes of interest. We conducted tests with coumarin and 2,4,6-trinitrotoluene (two solutes that were used in initial development of PLOT-cryo technology), naphthalene, aviation turbine kerosene, and diesel fuel, on a variety of matrices and test beds. We demonstrated that these analytes can be easily detected and reliably identified using the portable unit for analyte collection. By leveraging efficiency-boosting temperature control and the high flow rate multiple capillary wafer, very short collection times (as low as 3 s) yielded accurate detection. For diesel fuel spiked on glass beads, we determined a method detection limit below 1 ppm. We observed greater variability among separate samples analyzed with the portable unit than previously documented in work using the laboratory-based PLOT-cryo technology. We identify three likely sources that may help explain the additional variation: the use of a compressed air source to generate suction, matrix geometry, and variability in the local vapor concentration around the sampling probe as solute depletion occurs both locally around the probe and in the test bed as a whole. This field-portable adaptation of the PLOT-cryo approach has numerous and diverse potential applications. PMID:26726934

  11. Design and Test of a Deployable Radiation Cover for the REgolith X-Ray Imaging Spectrometer

    NASA Technical Reports Server (NTRS)

    Carte, David B.; Inamdar, Niraj K.; Jones, Michael P.; Masterson, Rebecca A.

    2014-01-01

    The REgolith X-ray Imaging Spectrometer (REXIS) instrument contains a one-time deployable radiation cover that is opened using a shape memory alloy actuator (a "Frangibolt") from TiNi Aerospace and two torsion springs. The door will be held closed by the bolt for several years in cold storage during travel to the target asteroid, Bennu, and it is imperative to gain confidence that the door will open at predicted operational temperatures. This paper briefly covers the main design features of the radiation cover and measures taken to mitigate risks to cover deployment. As the chosen FD04 model Frangibolt actuator has minimal flight heritage, the main focus of this paper is the testing, results and conclusions with the FD04 while discussing key lessons learned with respect to the use of the FD04 actuator in this application.

  12. An EEG-Based Person Authentication System with Open-Set Capability Combining Eye Blinking Signals

    PubMed Central

    Wu, Qunjian; Zeng, Ying; Zhang, Chi; Tong, Li; Yan, Bin

    2018-01-01

    The electroencephalogram (EEG) signal represents a subject’s specific brain activity patterns and is considered as an ideal biometric given its superior forgery prevention. However, the accuracy and stability of the current EEG-based person authentication systems are still unsatisfactory in practical application. In this paper, a multi-task EEG-based person authentication system combining eye blinking is proposed, which can achieve high precision and robustness. Firstly, we design a novel EEG-based biometric evoked paradigm using self- or non-self-face rapid serial visual presentation (RSVP). The designed paradigm could obtain a distinct and stable biometric trait from EEG with a lower time cost. Secondly, the event-related potential (ERP) features and morphological features are extracted from EEG signals and eye blinking signals, respectively. Thirdly, convolutional neural network and back propagation neural network are severally designed to gain the score estimation of EEG features and eye blinking features. Finally, a score fusion technology based on least square method is proposed to get the final estimation score. The performance of multi-task authentication system is improved significantly compared to the system using EEG only, with an increasing average accuracy from 92.4% to 97.6%. Moreover, open-set authentication tests for additional imposters and permanence tests for users are conducted to simulate the practical scenarios, which have never been employed in previous EEG-based person authentication systems. A mean false accepted rate (FAR) of 3.90% and a mean false rejected rate (FRR) of 3.87% are accomplished in open-set authentication tests and permanence tests, respectively, which illustrate the open-set authentication and permanence capability of our systems. PMID:29364848

  13. An EEG-Based Person Authentication System with Open-Set Capability Combining Eye Blinking Signals.

    PubMed

    Wu, Qunjian; Zeng, Ying; Zhang, Chi; Tong, Li; Yan, Bin

    2018-01-24

    The electroencephalogram (EEG) signal represents a subject's specific brain activity patterns and is considered as an ideal biometric given its superior forgery prevention. However, the accuracy and stability of the current EEG-based person authentication systems are still unsatisfactory in practical application. In this paper, a multi-task EEG-based person authentication system combining eye blinking is proposed, which can achieve high precision and robustness. Firstly, we design a novel EEG-based biometric evoked paradigm using self- or non-self-face rapid serial visual presentation (RSVP). The designed paradigm could obtain a distinct and stable biometric trait from EEG with a lower time cost. Secondly, the event-related potential (ERP) features and morphological features are extracted from EEG signals and eye blinking signals, respectively. Thirdly, convolutional neural network and back propagation neural network are severally designed to gain the score estimation of EEG features and eye blinking features. Finally, a score fusion technology based on least square method is proposed to get the final estimation score. The performance of multi-task authentication system is improved significantly compared to the system using EEG only, with an increasing average accuracy from 92.4% to 97.6%. Moreover, open-set authentication tests for additional imposters and permanence tests for users are conducted to simulate the practical scenarios, which have never been employed in previous EEG-based person authentication systems. A mean false accepted rate (FAR) of 3.90% and a mean false rejected rate (FRR) of 3.87% are accomplished in open-set authentication tests and permanence tests, respectively, which illustrate the open-set authentication and permanence capability of our systems.

  14. vitisFlower®: Development and Testing of a Novel Android-Smartphone Application for Assessing the Number of Grapevine Flowers per Inflorescence Using Artificial Vision Techniques.

    PubMed

    Aquino, Arturo; Millan, Borja; Gaston, Daniel; Diago, María-Paz; Tardaguila, Javier

    2015-08-28

    Grapevine flowering and fruit set greatly determine crop yield. This paper presents a new smartphone application for automatically counting, non-invasively and directly in the vineyard, the flower number in grapevine inflorescence photos by implementing artificial vision techniques. The application, called vitisFlower(®), firstly guides the user to appropriately take an inflorescence photo using the smartphone's camera. Then, by means of image analysis, the flowers in the image are detected and counted. vitisFlower(®) has been developed for Android devices and uses the OpenCV libraries to maximize computational efficiency. The application was tested on 140 inflorescence images of 11 grapevine varieties taken with two different devices. On average, more than 84% of flowers in the captures were found, with a precision exceeding 94%. Additionally, the application's efficiency on four different devices covering a wide range of the market's spectrum was also studied. The results of this benchmarking study showed significant differences among devices, although indicating that the application is efficiently usable even with low-range devices. vitisFlower is one of the first applications for viticulture that is currently freely available on Google Play.

  15. Development of Magneto-Resistive Angular Position Sensors for Space Applications

    NASA Astrophysics Data System (ADS)

    Hahn, Robert; Langendorf, Sven; Seifart, Klaus; Slatter, Rolf; Olberts, Bastian; Romera, Fernando

    2015-09-01

    Magnetic microsystems in the form of magneto- resistive (MR) sensors are firmly established in automobiles and industrial applications. They measure path, angle, electrical current, or magnetic fields. MR technology opens up new sensor possibilities in space applications and can be an enabling technology for optimal performance, high robustness and long lifetime at reasonable costs. In a recent assessment study performed by HTS GmbH and Sensitec GmbH under ESA Contract a market survey has confirmed that space industry has a very high interest in novel, contactless position sensors based on MR technology. Now, a detailed development stage is pursued, to advance the sensor design up to Engineering Qualification Model (EQM) level and to perform qualification testing for a representative pilot space application.The paper briefly reviews the basics of magneto- resistive effects and possible sensor applications and describes the key benefits of MR angular sensors with reference to currently operational industrial and space applications. The results of the assessment study are presented and potential applications and uses of contactless magneto-resistive angular sensors for spacecraft are identified. The baseline mechanical and electrical sensor design will be discussed. An outlook on the EQM development and qualification tests is provided.

  16. Characterization of the IEC 61000-4-6 Electromagnetic Clamp for Conducted-Immunity Testing

    NASA Astrophysics Data System (ADS)

    Grassi, F.; Pignari, S. A.; Spadacini, G.; Toscani, N.; Pelissou, P.

    2016-05-01

    A multiconductor transmission line model (MTL) is used to investigate the operation of the IEC 61000-4-6 electromagnetic (EM) clamp in a conducted-immunity test setup for aerospace applications. Aspects of interest include the performance of such a coupling device at very high frequencies (up to 1 GHz), and for extreme values of the common-mode impedance of equipment (short circuits, open circuits). The MTL model is finally exploited to predict the frequency response of coupling and decoupling factors defined in the IEC 61000-4-6 standard.

  17. Dual-Actuator Active Vibration-Control System

    NASA Technical Reports Server (NTRS)

    Kascak, Albert F.; Kiraly, Louis J.; Montague, Gerald T.; Palazzolo, Alan B.; Manchala, Daniel

    1994-01-01

    Dual-actuator active vibration-control (DAAVC) system is developmental system of type described in "Active Vibration Dampers for Rotating Machinery" (LEW-15427). System features sensors and actuators positioned and oriented at bearings to measure and counteract vibrations of shaft along either of two axes perpendicular to axis of rotation. Effective in damping vibrations of helicopter-engine test stand, making it safer to operate engine at speeds near and above first resonance of engine/test-stand system. Opens new opportunities for engine designers to draw more power from engine, and concept applicable to other rotating machines.

  18. First International Symposium on Strain Gauge Balances. Pt. 1

    NASA Technical Reports Server (NTRS)

    Tripp, John S. (Editor); Tcheng, Ping (Editor)

    1999-01-01

    The first International Symposium on Strain Gauge Balances was sponsored and held at NASA Langley Research Center during October 22-25, 1996. The symposium provided an open international forum for presentation, discussion, and exchange of technical information among wind tunnel test technique specialists and strain gauge balance designers. The Symposium also served to initiate organized professional activities among the participating and relevant international technical communities. Over 130 delegates from 15 countries were in attendance. The program opened with a panel discussion, followed by technical paper sessions, and guided tours of the National Transonic Facility (NTF) wind tunnel, a local commercial balance fabrication facility, and the LaRC balance calibration laboratory. The opening panel discussion addressed "Future Trends in Balance Development and Applications." Forty-six technical papers were presented in 11 technical sessions covering the following areas: calibration, automatic calibration, data reduction, facility reports, design, accuracy and uncertainty analysis, strain gauges, instrumentation, balance design, thermal effects, finite element analysis, applications, and special balances. At the conclusion of the Symposium, a steering committee representing most of the nations and several U.S. organizations attending the Symposium was established to initiate planning for a second international balance symposium, to be held in 1999 in the UK.

  19. First International Symposium on Strain Gauge Balances. Part 2

    NASA Technical Reports Server (NTRS)

    Tripp, John S (Editor); Tcheng, Ping (Editor)

    1999-01-01

    The first International Symposium on Strain Gauge Balances was sponsored and held at NASA Langley Research Center during October 22-25, 1996. The symposium provided an open international forum for presentation, discussion, and exchange of technical information among wind tunnel test technique specialists and strain gauge balance designers. The Symposium also served to initiate organized professional activities among the participating and relevant international technical communities. Over 130 delegates from 15 countries were in attendance. The program opened with a panel discussion, followed by technical paper sessions, and guided tours of the National Transonic Facility (NTF) wind tunnel, a local commercial balance fabrication facility, and the LaRC balance calibration laboratory. The opening panel discussion addressed "Future Trends in Balance Development and Applications." Forty-six technical papers were presented in 11 technical sessions covering the following areas: calibration, automatic calibration, data reduction, facility reports, design, accuracy and uncertainty analysis, strain gauges, instrumentation, balance design, thermal effects, finite element analysis, applications, and special balances. At the conclusion of the Symposium, a steering committee representing most of the nations and several U.S. organizations attending the Symposium was established to initiate planning for a second international balance symposium, to be held in 1999 in the UK.

  20. Dynamic mobility applications open source application development portal : Task 4 : system requirements specifications : final report.

    DOT National Transportation Integrated Search

    2016-10-12

    This document describes the System Requirements Specifications (SyRS) of the Dynamic Mobility Applications (DMA) Open Source Application Development Portal (OSADP) system in details according to IEEE-Std. 1233-1998. The requirement statements discuss...

  1. The Scientific Filesystem.

    PubMed

    Sochat, Vanessa

    2018-05-01

    Here, we present the Scientific Filesystem (SCIF), an organizational format that supports exposure of executables and metadata for discoverability of scientific applications. The format includes a known filesystem structure, a definition for a set of environment variables describing it, and functions for generation of the variables and interaction with the libraries, metadata, and executables located within. SCIF makes it easy to expose metadata, multiple environments, installation steps, files, and entry points to render scientific applications consistent, modular, and discoverable. A SCIF can be installed on a traditional host or in a container technology such as Docker or Singularity. We start by reviewing the background and rationale for the SCIF, followed by an overview of the specification and the different levels of internal modules ("apps") that the organizational format affords. Finally, we demonstrate that SCIF is useful by implementing and discussing several use cases that improve user interaction and understanding of scientific applications. SCIF is released along with a client and integration in the Singularity 2.4 software to quickly install and interact with SCIF. When used inside of a reproducible container, a SCIF is a recipe for reproducibility and introspection of the functions and users that it serves. We use SCIF to evaluate container software, provide metrics, serve scientific workflows, and execute a primary function under different contexts. To encourage collaboration and sharing of applications, we developed tools along with an open source, version-controlled, tested, and programmatically accessible web infrastructure. SCIF and associated resources are available at https://sci-f.github.io. The ease of using SCIF, especially in the context of containers, offers promise for scientists' work to be self-documenting and programatically parseable for maximum reproducibility. SCIF opens up an abstraction from underlying programming languages and packaging logic to work with scientific applications, opening up new opportunities for scientific software development.

  2. 43 CFR 2091.3 - Segregation and opening resulting from a proposal or application.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Segregation and opening resulting from a proposal or application. 2091.3 Section 2091.3 Public Lands: Interior Regulations Relating to Public Lands... LAWS AND RULES Segregation and Opening of Lands § 2091.3 Segregation and opening resulting from a...

  3. Duchenne Muscular Dystrophy: a Survey of Perspectives on Carrier Testing and Communication Within the Family.

    PubMed

    Hayes, Brenna; Hassed, Susan; Chaloner, Jae Lindsay; Aston, Christopher E; Guy, Carrie

    2016-06-01

    Carrier testing is widely available for multiple genetic conditions, and several professional organizations have created practice guidelines regarding appropriate clinical application and the testing of minors. Previous research has focused on carrier screening, predictive testing, and testing for X-linked conditions. However, family perspectives on carrier testing for X-linked lethal diseases have yet to be described. In this study, we explored communication within the family about carrier testing and the perspectives of mothers of sons with an X-linked lethal disease, Duchenne muscular dystrophy (DMD). Twenty-five mothers of sons with DMD participated in an anonymous online survey. Survey questions included multiple choice, Likert scale, and open ended, short answer questions. Analysis of the multiple choice and Likert scale questions revealed that most mothers preferred a gradual style of communication with their daughters regarding risk status. In addition, most participants reported having consulted with a genetic counselor and found it helpful. Comparisons between groups, analyzed using Fisher's exact tests, found no differences in preferred style due to mother's carrier status or having a daughter. Thematic analysis was conducted on responses to open ended questions. Themes identified included the impact of family implications, age and maturity, and a desire for autonomy regarding the decision to discuss and undergo carrier testing with at-risk daughters, particularly timing of these discussions. Implications for genetic counseling practice are discussed.

  4. LAVA Applications to Open Rotors

    NASA Technical Reports Server (NTRS)

    Kiris, Cetin C.; Housman, Jeff; Barad, Mike; Brehm, Christoph

    2015-01-01

    Outline: LAVA (Launch Ascent Vehicle Aerodynamics); Introduction; Acoustics Related Applications; LAVA Applications to Open Rotor; Structured Overset Grids; Cartesian Grid with Immersed Boundary; High Speed Case; High Speed Case with Plate Low Speed Case.

  5. WADeG Cell Phone

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2009-09-01

    The on cell phone software captures the images from the CMOS camera periodically, stores the pictures, and periodically transmits those images over the cellular network to the server. The cell phone software consists of several modules: CamTest.cpp, CamStarter.cpp, StreamIOHandler .cpp, and covertSmartDevice.cpp. The camera application on the SmartPhone is CamStarter, which is "the" user interface for the camera system. The CamStarter user interface allows a user to start/stop the camera application and transfer files to the server. The CamStarter application interfaces to the CamTest application through registry settings. Both the CamStarter and CamTest applications must be separately deployed on themore » smartphone to run the camera system application. When a user selects the Start button in CamStarter, CamTest is created as a process. The smartphone begins taking small pictures (CAPTURE mode), analyzing those pictures for certain conditions, and saving those pictures on the smartphone. This process will terminate when the user selects the Stop button. The camtest code spins off an asynchronous thread, StreamIOHandler, to check for pictures taken by the camera. The received image is then tested by StreamIOHandler to see if it meets certain conditions. If those conditions are met, the CamTest program is notified through the setting of a registry key value and the image is saved in a designated directory in a custom BMP file which includes a header and the image data. When the user selects the Transfer button in the CamStarter user interface, the covertsmartdevice code is created as a process. Covertsmartdevice gets all of the files in a designated directory, opens a socket connection to the server, sends each file, and then terminates.« less

  6. TANTAMOUNT TO FRAUD?: EXPLORING NON-DISCLOSURE OF GENETIC INFORMATION IN LIFE INSURANCE APPLICATIONS AS GROUNDS FOR POLICY RESCISSION.

    PubMed

    Prince, Anya E R

    2016-01-01

    Many genetic counselors recommend that individuals secure desired insurance policies, such as life insurance, prior to undergoing predictive genetic testing. It has been argued, however, that this practice is "tantamount to fraud" and that failure to disclose genetic test results, or conspiring to secure a policy before testing, opens an individual up to legal recourse. This debate traps affected individuals in a Catch-22. If they apply for life insurance and disclose a genetic test result, they may be denied. If they apply without disclosing the information, they may have committed fraud. The consequences of life insurance fraud are significant: If fraud is found on an application, a life insurer can rescind the policy, in some cases even after the individual has passed away. Such a rescission could leave family members or beneficiaries without the benefits of the life insurance policy payment after the individual's death and place them in in economic difficulty. Although it is clear that lying in response to a direct question about genetic testing would be tantamount to fraud, few, if any, life insurance applications currently include broad questions about genetic testing. This paper investigates whether non-disclosure of unasked for genetic information constitutes fraud and explores varying types of insurance questions that could conceivably be interpreted as seeking genetic information. Life insurance applicants generally have no duty to disclose unasked for information, including genetic information, on an application. However, given the complexities of genetic information, individuals may be exposed to fraud and rescission of their life insurance policy despite honest attempts to truthfully and completely answer all application questions.

  7. The Reality of Virtual Worlds: Pros and Cons of Their Application to Foreign Language Teaching

    ERIC Educational Resources Information Center

    Garrido-Iñigo, Paloma; Rodríguez-Moreno, Francisco

    2015-01-01

    This article presents our experience of testing the OpenSim platform as a tool in teaching French to 108 tourism students at Universidad Rey Juan Carlos (Madrid, Spain). The article begins with some theoretical reflections on the behaviour of the student when using a virtual platform by means of an avatar, and with our observations of how this…

  8. Push-out tests and evaluation of FRP perfobond rib shear connectors performance

    NASA Astrophysics Data System (ADS)

    Kolpasky, Ludvik; Ryjacek, Pavel

    2017-09-01

    The behavioural characteristics of FRP (fibre-reinforced polymer) perfobond rib shear connector was examined through push-out tests in order to verify the applicability for pedestrian bridge structure. The aim of this study is to determine interaction between high performance concrete slab and handmade FRP plate which represent web of the composite beam. Combination of these modern materials leads to structural system with both great load bearing capacity and also sufficient flexural stiffness of the composite element. Openings cut into the GFRP plate at a variable spacing allow GFRP reinforcement bars to be inserted to act as shear studs. Hand lay-up process can increase suitable properties of FRP for connection by perfobond rib shear connectors. In this study, three push-out tests on fiber-reinforced polymer were performed to investigate their shear behaviour. The results of the push-out tests on FRP perfobond rib shear connector indicates great promise for application in full scale structures.

  9. DEIVA: a web application for interactive visual analysis of differential gene expression profiles.

    PubMed

    Harshbarger, Jayson; Kratz, Anton; Carninci, Piero

    2017-01-07

    Differential gene expression (DGE) analysis is a technique to identify statistically significant differences in RNA abundance for genes or arbitrary features between different biological states. The result of a DGE test is typically further analyzed using statistical software, spreadsheets or custom ad hoc algorithms. We identified a need for a web-based system to share DGE statistical test results, and locate and identify genes in DGE statistical test results with a very low barrier of entry. We have developed DEIVA, a free and open source, browser-based single page application (SPA) with a strong emphasis on being user friendly that enables locating and identifying single or multiple genes in an immediate, interactive, and intuitive manner. By design, DEIVA scales with very large numbers of users and datasets. Compared to existing software, DEIVA offers a unique combination of design decisions that enable inspection and analysis of DGE statistical test results with an emphasis on ease of use.

  10. Post hoc support vector machine learning for impedimetric biosensors based on weak protein-ligand interactions.

    PubMed

    Rong, Y; Padron, A V; Hagerty, K J; Nelson, N; Chi, S; Keyhani, N O; Katz, J; Datta, S P A; Gomes, C; McLamore, E S

    2018-04-30

    Impedimetric biosensors for measuring small molecules based on weak/transient interactions between bioreceptors and target analytes are a challenge for detection electronics, particularly in field studies or in the analysis of complex matrices. Protein-ligand binding sensors have enormous potential for biosensing, but achieving accuracy in complex solutions is a major challenge. There is a need for simple post hoc analytical tools that are not computationally expensive, yet provide near real time feedback on data derived from impedance spectra. Here, we show the use of a simple, open source support vector machine learning algorithm for analyzing impedimetric data in lieu of using equivalent circuit analysis. We demonstrate two different protein-based biosensors to show that the tool can be used for various applications. We conclude with a mobile phone-based demonstration focused on the measurement of acetone, an important biomarker related to the onset of diabetic ketoacidosis. In all conditions tested, the open source classifier was capable of performing as well as, or better, than the equivalent circuit analysis for characterizing weak/transient interactions between a model ligand (acetone) and a small chemosensory protein derived from the tsetse fly. In addition, the tool has a low computational requirement, facilitating use for mobile acquisition systems such as mobile phones. The protocol is deployed through Jupyter notebook (an open source computing environment available for mobile phone, tablet or computer use) and the code was written in Python. For each of the applications, we provide step-by-step instructions in English, Spanish, Mandarin and Portuguese to facilitate widespread use. All codes were based on scikit-learn, an open source software machine learning library in the Python language, and were processed in Jupyter notebook, an open-source web application for Python. The tool can easily be integrated with the mobile biosensor equipment for rapid detection, facilitating use by a broad range of impedimetric biosensor users. This post hoc analysis tool can serve as a launchpad for the convergence of nanobiosensors in planetary health monitoring applications based on mobile phone hardware.

  11. A framework for integration of scientific applications into the OpenTopography workflow

    NASA Astrophysics Data System (ADS)

    Nandigam, V.; Crosby, C.; Baru, C.

    2012-12-01

    The NSF-funded OpenTopography facility provides online access to Earth science-oriented high-resolution LIDAR topography data, online processing tools, and derivative products. The underlying cyberinfrastructure employs a multi-tier service oriented architecture that is comprised of an infrastructure tier, a processing services tier, and an application tier. The infrastructure tier consists of storage, compute resources as well as supporting databases. The services tier consists of the set of processing routines each deployed as a Web service. The applications tier provides client interfaces to the system. (e.g. Portal). We propose a "pluggable" infrastructure design that will allow new scientific algorithms and processing routines developed and maintained by the community to be integrated into the OpenTopography system so that the wider earth science community can benefit from its availability. All core components in OpenTopography are available as Web services using a customized open-source Opal toolkit. The Opal toolkit provides mechanisms to manage and track job submissions, with the help of a back-end database. It allows monitoring of job and system status by providing charting tools. All core components in OpenTopography have been developed, maintained and wrapped as Web services using Opal by OpenTopography developers. However, as the scientific community develops new processing and analysis approaches this integration approach is not scalable efficiently. Most of the new scientific applications will have their own active development teams performing regular updates, maintenance and other improvements. It would be optimal to have the application co-located where its developers can continue to actively work on it while still making it accessible within the OpenTopography workflow for processing capabilities. We will utilize a software framework for remote integration of these scientific applications into the OpenTopography system. This will be accomplished by virtually extending the OpenTopography service over the various infrastructures running these scientific applications and processing routines. This involves packaging and distributing a customized instance of the Opal toolkit that will wrap the software application as an OPAL-based web service and integrate it into the OpenTopography framework. We plan to make this as automated as possible. A structured specification of service inputs and outputs along with metadata annotations encoded in XML can be utilized to automate the generation of user interfaces, with appropriate tools tips and user help features, and generation of other internal software. The OpenTopography Opal toolkit will also include the customizations that will enable security authentication, authorization and the ability to write application usage and job statistics back to the OpenTopography databases. This usage information could then be reported to the original service providers and used for auditing and performance improvements. This pluggable framework will enable the application developers to continue to work on enhancing their application while making the latest iteration available in a timely manner to the earth sciences community. This will also help us establish an overall framework that other scientific application providers will also be able to use going forward.

  12. Build, Buy, Open Source, or Web 2.0?: Making an Informed Decision for Your Library

    ERIC Educational Resources Information Center

    Fagan, Jody Condit; Keach, Jennifer A.

    2010-01-01

    When improving a web presence, today's libraries have a choice: using a free Web 2.0 application, opting for open source, buying a product, or building a web application. This article discusses how to make an informed decision for one's library. The authors stress that deciding whether to use a free Web 2.0 application, to choose open source, to…

  13. The OPEN Migration Platform Architecture

    NASA Astrophysics Data System (ADS)

    Martin, Miquel

    This chapter establishes a common understanding of the meaning of migration, and introduces the OPEN functionalities, which enable application migration. We start by discussing the various definitions of migration, before focusing on the OPEN take on the concept. The chapter then covers our proposed architecture , as well as the functionality required, both from the server and the client side (i.e. the applications) in order to enable application migration.

  14. 42 CFR 84.93 - Gas flow test; open-circuit apparatus.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Gas flow test; open-circuit apparatus. 84.93...-Contained Breathing Apparatus § 84.93 Gas flow test; open-circuit apparatus. (a) A static-flow test will be performed on all open-circuit apparatus. (b) The flow from the apparatus shall be greater than 200 liters...

  15. 42 CFR 84.93 - Gas flow test; open-circuit apparatus.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Gas flow test; open-circuit apparatus. 84.93...-Contained Breathing Apparatus § 84.93 Gas flow test; open-circuit apparatus. (a) A static-flow test will be performed on all open-circuit apparatus. (b) The flow from the apparatus shall be greater than 200 liters...

  16. Clinical Neuropathology practice news 1-2014: Pyrosequencing meets clinical and analytical performance criteria for routine testing of MGMT promoter methylation status in glioblastoma

    PubMed Central

    Preusser, Matthias; Berghoff, Anna S.; Manzl, Claudia; Filipits, Martin; Weinhäusel, Andreas; Pulverer, Walter; Dieckmann, Karin; Widhalm, Georg; Wöhrer, Adelheid; Knosp, Engelbert; Marosi, Christine; Hainfellner, Johannes A.

    2014-01-01

    Testing of the MGMT promoter methylation status in glioblastoma is relevant for clinical decision making and research applications. Two recent and independent phase III therapy trials confirmed a prognostic and predictive value of the MGMT promoter methylation status in elderly glioblastoma patients. Several methods for MGMT promoter methylation testing have been proposed, but seem to be of limited test reliability. Therefore, and also due to feasibility reasons, translation of MGMT methylation testing into routine use has been protracted so far. Pyrosequencing after prior DNA bisulfite modification has emerged as a reliable, accurate, fast and easy-to-use method for MGMT promoter methylation testing in tumor tissues (including formalin-fixed and paraffin-embedded samples). We performed an intra- and inter-laboratory ring trial which demonstrates a high analytical performance of this technique. Thus, pyrosequencing-based assessment of MGMT promoter methylation status in glioblastoma meets the criteria of high analytical test performance and can be recommended for clinical application, provided that strict quality control is performed. Our article summarizes clinical indications, practical instructions and open issues for MGMT promoter methylation testing in glioblastoma using pyrosequencing. PMID:24359605

  17. Eye/head tracking technology to improve HCI with iPad applications.

    PubMed

    Lopez-Basterretxea, Asier; Mendez-Zorrilla, Amaia; Garcia-Zapirain, Begoña

    2015-01-22

    In order to improve human computer interaction (HCI) for people with special needs, this paper presents an alternative form of interaction, which uses the iPad's front camera and eye/head tracking technology. With this functional nature/capability operating in the background, the user can control already developed or new applications for the iPad by moving their eyes and/or head. There are many techniques, which are currently used to detect facial features, such as eyes or even the face itself. Open source bookstores exist for such purpose, such as OpenCV, which enable very reliable and accurate detection algorithms to be applied, such as Haar Cascade using very high-level programming. All processing is undertaken in real time, and it is therefore important to pay close attention to the use of limited resources (processing capacity) of devices, such as the iPad. The system was validated in tests involving 22 users of different ages and characteristics (people with dark and light-colored eyes and with/without glasses). These tests are performed to assess user/device interaction and to ascertain whether it works properly. The system obtained an accuracy of between 60% and 100% in the three test exercises taken into consideration. The results showed that the Haar Cascade had a significant effect by detecting faces in 100% of cases, unlike eyes and the pupil where interference (light and shade) evidenced less effectiveness. In addition to ascertaining the effectiveness of the system via these exercises, the demo application has also helped to show that user constraints need not affect the enjoyment and use of a particular type of technology. In short, the results obtained are encouraging and these systems may continue to be developed if extended and updated in the future.

  18. A Grassroots Remote Sensing Toolkit Using Live Coding, Smartphones, Kites and Lightweight Drones.

    PubMed

    Anderson, K; Griffiths, D; DeBell, L; Hancock, S; Duffy, J P; Shutler, J D; Reinhardt, W J; Griffiths, A

    2016-01-01

    This manuscript describes the development of an android-based smartphone application for capturing aerial photographs and spatial metadata automatically, for use in grassroots mapping applications. The aim of the project was to exploit the plethora of on-board sensors within modern smartphones (accelerometer, GPS, compass, camera) to generate ready-to-use spatial data from lightweight aerial platforms such as drones or kites. A visual coding 'scheme blocks' framework was used to build the application ('app'), so that users could customise their own data capture tools in the field. The paper reports on the coding framework, then shows the results of test flights from kites and lightweight drones and finally shows how open-source geospatial toolkits were used to generate geographical information system (GIS)-ready GeoTIFF images from the metadata stored by the app. Two Android smartphones were used in testing-a high specification OnePlus One handset and a lower cost Acer Liquid Z3 handset, to test the operational limits of the app on phones with different sensor sets. We demonstrate that best results were obtained when the phone was attached to a stable single line kite or to a gliding drone. Results show that engine or motor vibrations from powered aircraft required dampening to ensure capture of high quality images. We demonstrate how the products generated from the open-source processing workflow are easily used in GIS. The app can be downloaded freely from the Google store by searching for 'UAV toolkit' (UAV toolkit 2016), and used wherever an Android smartphone and aerial platform are available to deliver rapid spatial data (e.g. in supporting decision-making in humanitarian disaster-relief zones, in teaching or for grassroots remote sensing and democratic mapping).

  19. Eye/Head Tracking Technology to Improve HCI with iPad Applications

    PubMed Central

    Lopez-Basterretxea, Asier; Mendez-Zorrilla, Amaia; Garcia-Zapirain, Begoña

    2015-01-01

    In order to improve human computer interaction (HCI) for people with special needs, this paper presents an alternative form of interaction, which uses the iPad's front camera and eye/head tracking technology. With this functional nature/capability operating in the background, the user can control already developed or new applications for the iPad by moving their eyes and/or head. There are many techniques, which are currently used to detect facial features, such as eyes or even the face itself. Open source bookstores exist for such purpose, such as OpenCV, which enable very reliable and accurate detection algorithms to be applied, such as Haar Cascade using very high-level programming. All processing is undertaken in real time, and it is therefore important to pay close attention to the use of limited resources (processing capacity) of devices, such as the iPad. The system was validated in tests involving 22 users of different ages and characteristics (people with dark and light-colored eyes and with/without glasses). These tests are performed to assess user/device interaction and to ascertain whether it works properly. The system obtained an accuracy of between 60% and 100% in the three test exercises taken into consideration. The results showed that the Haar Cascade had a significant effect by detecting faces in 100% of cases, unlike eyes and the pupil where interference (light and shade) evidenced less effectiveness. In addition to ascertaining the effectiveness of the system via these exercises, the demo application has also helped to show that user constraints need not affect the enjoyment and use of a particular type of technology. In short, the results obtained are encouraging and these systems may continue to be developed if extended and updated in the future. PMID:25621603

  20. Assessment of the possible reuse of MSW coming from landfill mining of old open dumpsites.

    PubMed

    Masi, S; Caniani, D; Grieco, E; Lioi, D S; Mancini, I M

    2014-03-01

    The present study addresses the theme of recycling potential of old open dumpsites by using landfill mining. Attention is focused on the possible reuse of the residual finer fraction (<4 mm), which constitutes more than 60% of the total mined material, sampled in the old open dumpsite of Lavello (Southern Italy). We propose a protocol of analysis of the landfill material that links chemical analyses and environmental bioassays. This protocol is used to evaluate the compatibility of the residual matrix for the disposal in temporary storages and the formation of "bio-soils" to be used in geo-environmental applications, such as the construction of barrier layers of landfills, or in environmental remediation activities. Attention is mainly focused on the presence of heavy metals and on the possible interaction with test organisms. Chemical analyses of the residual matrix and leaching tests showed that the concentration of heavy metals is always below the legislation limits. Biological acute tests (with Lepidum sativum, Vicia faba and Lactuca sativa) do not emphasize adverse effects to the growth of the plant species, except the bioassay with V. faba, which showed a dose-response effect. The new developed chronic bioassay test with Spartium junceum showed a good adaptation to stress conditions induced by the presence of the mined landfill material. In conclusion, the conducted experimental activities demonstrated the suitability of the material to be used for different purposes. Copyright © 2013 Elsevier Ltd. All rights reserved.

  1. Specifications and implementation of the RT MHD control system for the EC launcher of FTU

    NASA Astrophysics Data System (ADS)

    Galperti, C.; Alessi, E.; Boncagni, L.; Bruschi, A.; Granucci, G.; Grosso, A.; Iannone, F.; Marchetto, C.; Nowak, S.; Panella, M.; Sozzi, C.; Tilia, B.

    2012-09-01

    To perform real time plasma control experiments using EC heating waves by using the new fast launcher installed on FTU a dedicated data acquisition and elaboration system has been designed recently. A prototypical version of the acquisition/control system has been recently developed and will be tested on FTU machine in its next experimental campaign. The open-source framework MARTe (Multi-threaded Application Real-Time executor) on Linux/RTAI real-time operating system has been chosen as software platform to realize the control system. Standard open-architecture industrial PCs, based either on VME bus and CompactPCI bus equipped with standard input/output cards are the chosen hardware platform.

  2. Analysis, testing, and evaluation of faulted and unfaulted Wye, Delta, and open Delta connected electromechanical actuators

    NASA Technical Reports Server (NTRS)

    Nehl, T. W.; Demerdash, N. A.

    1983-01-01

    Mathematical models capable of simulating the transient, steady state, and faulted performance characteristics of various brushless dc machine-PSA (power switching assembly) configurations were developed. These systems are intended for possible future use as primemovers in EMAs (electromechanical actuators) for flight control applications. These machine-PSA configurations include wye, delta, and open-delta connected systems. The research performed under this contract was initially broken down into the following six tasks: development of mathematical models for various machine-PSA configurations; experimental validation of the model for failure modes; experimental validation of the mathematical model for shorted turn-failure modes; tradeoff study; and documentation of results and methodology.

  3. Relation Between Inflammables and Ignition Sources in Aircraft Environments

    NASA Technical Reports Server (NTRS)

    Scull, Wilfred E

    1950-01-01

    A literature survey was conducted to determine the relation between aircraft ignition sources and inflammables. Available literature applicable to the problem of aircraft fire hazards is analyzed and, discussed herein. Data pertaining to the effect of many variables on ignition temperatures, minimum ignition pressures, and minimum spark-ignition energies of inflammables, quenching distances of electrode configurations, and size of openings incapable of flame propagation are presented and discussed. The ignition temperatures and the limits of inflammability of gasoline in air in different test environments, and the minimum ignition pressure and the minimum size of openings for flame propagation of gasoline - air mixtures are included. Inerting of gasoline - air mixtures is discussed.

  4. Validation of OpenFoam for heavy gas dispersion applications.

    PubMed

    Mack, A; Spruijt, M P N

    2013-11-15

    In the present paper heavy gas dispersion calculations were performed with OpenFoam. For a wind tunnel test case, numerical data was validated with experiments. For a full scale numerical experiment, a code to code comparison was performed with numerical results obtained from Fluent. The validation was performed in a gravity driven environment (slope), where the heavy gas induced the turbulence. For the code to code comparison, a hypothetical heavy gas release into a strongly turbulent atmospheric boundary layer including terrain effects was selected. The investigations were performed for SF6 and CO2 as heavy gases applying the standard k-ɛ turbulence model. A strong interaction of the heavy gas with the turbulence is present which results in a strong damping of the turbulence and therefore reduced heavy gas mixing. Especially this interaction, based on the buoyancy effects, was studied in order to ensure that the turbulence-buoyancy coupling is the main driver for the reduced mixing and not the global behaviour of the turbulence modelling. For both test cases, comparisons were performed between OpenFoam and Fluent solutions which were mainly in good agreement with each other. Beside steady state solutions, the time accuracy was investigated. In the low turbulence environment (wind tunnel test) which for both codes (laminar solutions) was in good agreement, also with the experimental data. The turbulent solutions of OpenFoam were in much better agreement with the experimental results than the Fluent solutions. Within the strong turbulence environment, both codes showed an excellent comparability. Copyright © 2013 Elsevier B.V. All rights reserved.

  5. Development of a low cost pupillometer-eyetracker and applications

    NASA Astrophysics Data System (ADS)

    Bianchetti, Arturo; Perez, Liliana I.; Comastri, Silvia A.

    2013-11-01

    The determination of ocular pupil diameter and gaze direction is important in various psychophysical and cognitive tests and can be accomplished using commercial, academic or open-source devices. In this work we develop a table-top pupillometer eyetracker termed Blick, the hardware costs 50 dollars and the software is open source (https://github.com/abianchetti/blick). The hardware is mounted in a portable holder and comprises an illumination system (two infrared LEDs generating 0.13 W/m2 at 22 cm) and a detection system (containing an USB camera, an infrared filter and a 16mm lens system) The software, programmed in C++ using OpenCV and cvblob libraries, processes eye images in real time and supplies plots and tables of pupil diameter and gaze direction and a video of the eye. As applications, capturing the right eye of six young emmetropes and after performing the pixel-mm and homographic calibrations (required to determine diameter in mm and gaze direction), we conduct three tests. The corresponding tasks are to detect mistakes in three series of four poker cards, to recognize letters F between distractors and to write a sentence via eye movements using Blick as eye tracker and the tool Dasher (MacKayśs Cambridge Group). We obtain that Blicḱs performance is satisfactory (errors being 0.05 mm in pupil diameter and 1 degree in gaze direction); that there are slight pupil dilations when subjects used to playing cards find mistakes and when some subjects find targets and, finally, that Blick can be employed as eyetracker to allow communication of disabled persons.

  6. [Application of locomotor activity test to evaluate functional injury after global cerebral ischemia in C57BL/6 mice].

    PubMed

    Zhang, Li-quan; Xu, Jia-ni; Wang, Zhen-zhen; Zeng, Li-jun; Ye, Yi-lu; Zhang, Wei-ping; Wei, Er-qing; Zhang, Qi

    2014-05-01

    To evaluate the application of locomotor activity test in functional injury after global cerebral ischemia (GCI) in C57BL/6 mice. GCI was induced by bilateral carotid arteries occlusion for 30 min in C57BL/6 mice. Mice were divided into sham group, GCI group and minocycline group. Saline or minocycline (45 mg/kg) was i.p. injected once daily for 6 d after ischemia. At Day 6 after ischemia, locomotor activity was recorded for 1 h in open field test. Total distance, central distance, central distance ratio, periphery distance, periphery distance ratio, central time and periphery time were used to evaluate the behavior characteristics of locomotor activity in C57BL/6 mice after ischemia. The survival neuron density was detected by Nissl staining in hippocampus, cortex and striatum. Compared with sham group, total distance, central distance and central time increased and periphery time decreased in C57BL/6 mice after GCI (Ps<0.05). However, minocycline significantly reduced the central distance and central time and increased the periphery time (Ps<0.05). Neurons were damaged in hippocampus, cortex and striatum after GCI, which manifested by decreased neurons and the most serious damage in hippocampal CA1 region. Minocycline significantly improved the neuron appearance and increased the neuron number in hippocampus and striatum (P<0.001 or P<0.05). Locomotor activity in open field test can objectively evaluate the behavior injury after GCI in mice. Central distance and central time can be used as indexes of quantitative assessment.

  7. Quantitative repeated open application testing with a rinse-off product in methyldibromo glutaronitrile-sensitive patients: results of the IVDK.

    PubMed

    Heratizadeh, Annice; Killig, Claudia; Worm, Margitta; Soost, Stephanie; Simon, Dagmar; Bauer, Andrea; Mahler, Vera; Schuster, Christian; Szliska, Christiane; Frambach, Yvonne; Eben, Ricarda; Werfel, Thomas; Uter, Wolfgang; Schnuch, Axel

    2010-06-01

    While the use of methyldibromo glutaronitrile (MDBGN) in leave-on products is clearly associated with high sensitization or elicitation risk, such a clear-cut relation could be questioned with regard to rinse-off products. The objective of this study was to find a maximum non-eliciting concentration for rinse-off products in MDBGN patch test-positive patients. We performed a use-related test [repeated open application test (ROAT)] in patients sensitized to MDBGN with a liquid soap containing three concentrations of MDBGN (50, 200, and 400 p.p.m. MDBGN, respectively). The soap at 50 p.p.m. was used twice daily for 4 weeks. If no reaction of the skin was observed, the product with the next higher concentration was used for another 4 weeks, etc. In total, 32/37 evaluated cases [86.5%; lower exact one-sided 95% confidence limit (CL): 73.7%] did not react to any of the preparations. The remaining reacted as follows: 1/37 reacted to 50 p.p.m., 3/37 to 200 p.p.m., and 1/37 to 400 p.p.m. The cumulative non-response to 50 p.p.m. was 97.3% (lower CL: 87.8%). The majority of subjects sensitized to MDBGN-tolerated rinse-off products containing a maximum concentration of 400 p.p.m. A concentration in rinse-off products in the range of 50 p.p.m. could be regarded as safe for most individuals already sensitized. These concentrations will presumably prevent induction (sensitization) also.

  8. Open Admissions: A Bibliography for Research and Application.

    ERIC Educational Resources Information Center

    Shrier, Irene; Lavin, David E.

    This bibliography presents materials for research and application of open admissions policies in higher education. Sections cover: open admissions; factors influencing high school graduates to attend college; disadvantaged and minority students; precollege and special programs; English and reading skills; general compensatory programs; dropouts;…

  9. Implementation and Testing of Low Cost Uav Platform for Orthophoto Imaging

    NASA Astrophysics Data System (ADS)

    Brucas, D.; Suziedelyte-Visockiene, J.; Ragauskas, U.; Berteska, E.; Rudinskas, D.

    2013-08-01

    Implementation of Unmanned Aerial Vehicles for civilian applications is rapidly increasing. Technologies which were expensive and available only for military use have recently spread on civilian market. There is a vast number of low cost open source components and systems for implementation on UAVs available. Using of low cost hobby and open source components ensures considerable decrease of UAV price, though in some cases compromising its reliability. In Space Science and Technology Institute (SSTI) in collaboration with Vilnius Gediminas Technical University (VGTU) researches have been performed in field of constructing and implementation of small UAVs composed of low cost open source components (and own developments). Most obvious and simple implementation of such UAVs - orthophoto imaging with data download and processing after the flight. The construction, implementation of UAVs, flight experience, data processing and data implementation will be further covered in the paper and presentation.

  10. Testing the Applicability of Nernst-Planck Theory in Ion Channels: Comparisons with Brownian Dynamics Simulations

    PubMed Central

    Song, Chen; Corry, Ben

    2011-01-01

    The macroscopic Nernst-Planck (NP) theory has often been used for predicting ion channel currents in recent years, but the validity of this theory at the microscopic scale has not been tested. In this study we systematically tested the ability of the NP theory to accurately predict channel currents by combining and comparing the results with those of Brownian dynamics (BD) simulations. To thoroughly test the theory in a range of situations, calculations were made in a series of simplified cylindrical channels with radii ranging from 3 to 15 Å, in a more complex ‘catenary’ channel, and in a realistic model of the mechanosensitive channel MscS. The extensive tests indicate that the NP equation is applicable in narrow ion channels provided that accurate concentrations and potentials can be input as the currents obtained from the combination of BD and NP match well with those obtained directly from BD simulations, although some discrepancies are seen when the ion concentrations are not radially uniform. This finding opens a door to utilising the results of microscopic simulations in continuum theory, something that is likely to be useful in the investigation of a range of biophysical and nano-scale applications and should stimulate further studies in this direction. PMID:21731672

  11. Testing the applicability of Nernst-Planck theory in ion channels: comparisons with Brownian dynamics simulations.

    PubMed

    Song, Chen; Corry, Ben

    2011-01-01

    The macroscopic Nernst-Planck (NP) theory has often been used for predicting ion channel currents in recent years, but the validity of this theory at the microscopic scale has not been tested. In this study we systematically tested the ability of the NP theory to accurately predict channel currents by combining and comparing the results with those of Brownian dynamics (BD) simulations. To thoroughly test the theory in a range of situations, calculations were made in a series of simplified cylindrical channels with radii ranging from 3 to 15 Å, in a more complex 'catenary' channel, and in a realistic model of the mechanosensitive channel MscS. The extensive tests indicate that the NP equation is applicable in narrow ion channels provided that accurate concentrations and potentials can be input as the currents obtained from the combination of BD and NP match well with those obtained directly from BD simulations, although some discrepancies are seen when the ion concentrations are not radially uniform. This finding opens a door to utilising the results of microscopic simulations in continuum theory, something that is likely to be useful in the investigation of a range of biophysical and nano-scale applications and should stimulate further studies in this direction.

  12. Open-Book Tests to Complement Assessment-Programmes: Analysis of Open and Closed-Book Tests

    ERIC Educational Resources Information Center

    Heijne-penninga, M.; Kuks, J. B. M.; Schonrock-adema, J.; Snijders, T. A. B.; Cohen-schotanus, J.

    2008-01-01

    Today's health sciences educational programmes have to deal with a growing and changing amount of knowledge. It is becoming increasingly important for students to be able to use and manage knowledge. We suggest incorporating open-book tests in assessment programmes to meet these changes. This view on the use of open-book tests is discussed and the…

  13. Development and Evaluation of the Next Generation of Meteoroid and Orbital Debris Shields

    NASA Astrophysics Data System (ADS)

    Ryan, Shannon; Christiansen, Eric

    2009-06-01

    Recent events such as the Chinese anti-satellite missile test in January 2007 and the collision between a Russian Cosmos satellite and US Iridium satellite in February 2009 are responsible for a rapid increase in the population of orbital debris in Low Earth Orbit (LEO). Without active debris removal strategies the debris population in key orbits will continue to increase, requiring enhanced shielding capabilities to maintain allowable penetration risks. One of the more promising developments in recent years for meteoroid and orbital debris shielding (MMOD) is the application of open cell foams. Although shielding onboard the International Space Station is the most capable ever flown, the most proficient configuration (stuffed Whipple shield) requires an additional ˜30% of the shielding mass for non-ballistic requirements (e.g. stiffeners, fasteners, etc.). Open cell foam structures provide similar mechanical performance to more traditional structural components such as honeycomb sandwich panels, as well as improved projectile fragmentation and melting as a result of repeated shocking by foam ligaments. In this paper, the preliminary results of an extensive hypervelocity impact test program on next generation MMOD shielding configurations incorporating open-cell metallic foams are reported.

  14. Development and Evaluation of the Next Generation of Meteoroid and Orbital Debris Shields

    NASA Technical Reports Server (NTRS)

    Christiansen, E.; Lear, D.; Ryan, S.

    2009-01-01

    Recent events such as the Chinese anti-satellite missile test in January 2007 and the collision between a Russian Cosmos satellite and US Iridium satellite in February 2009 are responsible for a rapid increase in the population of orbital debris in Low Earth Orbit (LEO). Without active debris removal strategies the debris population in key orbits will continue to increase, requiring enhanced shielding capabilities to maintain allowable penetration risks. One of the more promising developments in recent years for meteoroid and orbital debris shielding (MMOD) is the application of open cell foams. Although shielding onboard the International Space Station is the most capable ever flown, the most proficient configuration (stuffed Whipple shield) requires an additional 30% of the shielding mass for non-ballistic requirements (e.g. stiffeners, fasteners, etc.). Open cell foam structures provide similar mechanical performance to more traditional structural components such as honeycomb sandwich panels, as well as improved projectile fragmentation and melting as a result of repeated shocking by foam ligaments. In this paper, the preliminary results of an extensive hypervelocity impact test program on next generation MMOD shielding configurations incorporating open-cell metallic foams are reported.

  15. OpenGL in Multi-User Web-Based Applications

    NASA Astrophysics Data System (ADS)

    Szostek, K.; Piórkowski, A.

    In this article construction and potential of OpenGL multi-user web-based application are presented. The most common technologies like: .NET ASP, Java and Mono were used with specific OpenGL libraries to visualize tree-dimensional medical data. The most important conclusion of this work is that server side applications can easily take advantage of fast GPU and produce efficient results of advanced computation just like the visualization.

  16. Development of an open-path gas analyser for plume detection in security applications

    NASA Astrophysics Data System (ADS)

    Hay, Kenneth G.; Norberg, Ola; Normand, Erwan; Önnerud, Hans; Black, Paul

    2017-04-01

    We present here an open-path analyser, initially intended for security applications, specifically for the detection of gas plumes from illicit improvised explosive device (IED) manufacturing. Subsequently, the analysers were adapted for methane measurement and used to investigate its applicability for leak detection in different scenarios (e.g. unconventional gas extraction sites). Preliminary results showed consistent measurements of gas plumes in the open path.

  17. Benchmarking an unstructured grid sediment model in an energetic estuary

    DOE PAGES

    Lopez, Jesse E.; Baptista, António M.

    2016-12-14

    A sediment model coupled to the hydrodynamic model SELFE is validated against a benchmark combining a set of idealized tests and an application to a field-data rich energetic estuary. After sensitivity studies, model results for the idealized tests largely agree with previously reported results from other models in addition to analytical, semi-analytical, or laboratory results. Results of suspended sediment in an open channel test with fixed bottom are sensitive to turbulence closure and treatment for hydrodynamic bottom boundary. Results for the migration of a trench are very sensitive to critical stress and erosion rate, but largely insensitive to turbulence closure.more » The model is able to qualitatively represent sediment dynamics associated with estuarine turbidity maxima in an idealized estuary. Applied to the Columbia River estuary, the model qualitatively captures sediment dynamics observed by fixed stations and shipborne profiles. Representation of the vertical structure of suspended sediment degrades when stratification is underpredicted. Across all tests, skill metrics of suspended sediments lag those of hydrodynamics even when qualitatively representing dynamics. The benchmark is fully documented in an openly available repository to encourage unambiguous comparisons against other models.« less

  18. FermiLib v0.1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    MCCLEAN, JARROD; HANER, THOMAS; STEIGER, DAMIAN

    FermiLib is an open source software package designed to facilitate the development and testing of algorithms for simulations of fermionic systems on quantum computers. Fermionic simulations represent an important application of early quantum devices with a lot of potential high value targets, such as quantum chemistry for the development of new catalysts. This software strives to provide a link between the required domain expertise in specific fermionic applications and quantum computing to enable more users to directly interface with, and develop for, these applications. It is an extensible Python library designed to interface with the high performance quantum simulator, ProjectQ,more » as well as application specific software such as PSI4 from the domain of quantum chemistry. Such software is key to enabling effective user facilities in quantum computation research.« less

  19. Influence of various amount of diatomaceous earth used as cement substitute on mechanical properties of cement paste

    NASA Astrophysics Data System (ADS)

    Pokorný, Jaroslav; Pavlíková, Milena; Medved, Igor; Pavlík, Zbyšek; Zahálková, Jana; Rovnaníková, Pavla; Černý, Robert

    2016-06-01

    Active silica containing materials in the sub-micrometer size range are commonly used for modification of strength parameters and durability of cement based composites. In addition, these materials also assist to accelerate cement hydration. In this paper, two types of diatomaceous earths are used as partial cement replacement in composition of cement paste mixtures. For raw binders, basic physical and chemical properties are studied. The chemical composition of tested materials is determined using classical chemical analysis combined with XRD method that allowed assessment of SiO2 amorphous phase content. For all tested mixtures, initial and final setting times are measured. Basic physical and mechanical properties are measured on hardened paste samples cured 28 days in water. Here, bulk density, matrix density, total open porosity, compressive and flexural strength, are measured. Relationship between compressive strength and total open porosity is studied using several empirical models. The obtained results give evidence of high pozzolanic activity of tested diatomite earths. Their application leads to the increase of both initial and final setting times, decrease of compressive strength, and increase of flexural strength.

  20. Open Smart Energy Gateway (OpenSEG)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    The Open Smart Energy Gateway (OpenSEG) aims to provide near-real time smart meter data to consumers without the delays or latencies associated with it being transported to the utility data center and then back to the consumer's application. To do this, the gateway queries the local Smart Meter to which it is bound to get energy consumption information at pre-defined intervals (minimum interval is 4 seconds). OpenSEG then stores the resulting data internally for retrieval by an external application.

  1. Assessing biodiversity on the farm scale as basis for ecosystem service payments.

    PubMed

    von Haaren, Christina; Kempa, Daniela; Vogel, Katrin; Rüter, Stefan

    2012-12-30

    Ecosystem services payments must be based on a standardised transparent assessment of the goods and services provided. This is especially relevant in the context of EU agri-environmental programs, but also for organic-food companies that foster environmental services on their contractor farms. Addressing the farm scale is important because land users/owners are major recipients of payments and they could be more involved in data generation and conservation management. A standardised system for measuring on-farm biodiversity does not yet exist that concentrates on performance indicators and includes farmers in generating information. A method is required that produces ordinal or metric scaled assessment results as well as management measures. Another requirement is the ease of application, which includes the ease of gathering input data and understandability. In order to respond to this need, we developed a method which is designed for automated application in an open source farm assessment system named MANUELA. The method produces an ordinal scale assessment of biodiversity that includes biotopes, species, biotope connectivity and the influence of land use. In addition, specific measures for biotope types are proposed. The open source geographical information system OpenJump is used for the implementation of MANUELA. The results of the trial applications and robustness tests show that the assessment can be implemented, for the most part, using existing information as well as data available from farmers or advisors. The results are more sensitive for showing on-farm achievements and changes than existing biotope-type classifications. Such a differentiated classification is needed as a basis for ecosystem service payments and for designing effective measures. The robustness of the results with respect to biotope connectivity is comparable to that of complex models, but it should be further improved. Interviews with the test farmers substantiate that the assessment methods can be implemented on farms and they are understood by farmers. Copyright © 2012 Elsevier Ltd. All rights reserved.

  2. OpenLMD, multimodal monitoring and control of LMD processing

    NASA Astrophysics Data System (ADS)

    Rodríguez-Araújo, Jorge; García-Díaz, Antón

    2017-02-01

    This paper presents OpenLMD, a novel open-source solution for on-line multimodal monitoring of Laser Metal Deposition (LMD). The solution is also applicable to a wider range of laser-based applications that require on-line control (e.g. laser welding). OpenLMD is a middleware that enables the orchestration and virtualization of a LMD robot cell, using several open-source frameworks (e.g. ROS, OpenCV, PCL). The solution also allows reconfiguration by easy integration of multiple sensors and processing equipment. As a result, OpenLMD delivers significant advantages over existing monitoring and control approaches, such as improved scalability, and multimodal monitoring and data sharing capabilities.

  3. The Shock and Vibration Bulletin. Part 2. Opening Session, Panel Session, Shock Testing and Analysis, Fluid-structure Topics

    DTIC Science & Technology

    1976-08-01

    would like to 20 g’s rms and this would be instead of the to mention is that the IES under the leadership present single frequency non resonant 2.2 g am...Vol. 11, 1970. 19. Thomson, W. T., Vibration Theory 7. Cremer , L. and Heckl, M. and and Applications, Prentice-Hall, Ungar, E. E., Structure-Borne

  4. Comparison of Origin 2000 and Origin 3000 Using NAS Parallel Benchmarks

    NASA Technical Reports Server (NTRS)

    Turney, Raymond D.

    2001-01-01

    This report describes results of benchmark tests on the Origin 3000 system currently being installed at the NASA Ames National Advanced Supercomputing facility. This machine will ultimately contain 1024 R14K processors. The first part of the system, installed in November, 2000 and named mendel, is an Origin 3000 with 128 R12K processors. For comparison purposes, the tests were also run on lomax, an Origin 2000 with R12K processors. The BT, LU, and SP application benchmarks in the NAS Parallel Benchmark Suite and the kernel benchmark FT were chosen to determine system performance and measure the impact of changes on the machine as it evolves. Having been written to measure performance on Computational Fluid Dynamics applications, these benchmarks are assumed appropriate to represent the NAS workload. Since the NAS runs both message passing (MPI) and shared-memory, compiler directive type codes, both MPI and OpenMP versions of the benchmarks were used. The MPI versions used were the latest official release of the NAS Parallel Benchmarks, version 2.3. The OpenMP versiqns used were PBN3b2, a beta version that is in the process of being released. NPB 2.3 and PBN 3b2 are technically different benchmarks, and NPB results are not directly comparable to PBN results.

  5. Evaluation of the attractive force of different types of new-generation magnetic attachment systems.

    PubMed

    Akin, Hakan; Coskun, M Emre; Akin, E Gulsah; Ozdemir, A Kemal

    2011-03-01

    Rare earth magnets have been used in prosthodontics, but their tendency for corrosion in the oral cavity and insufficient attractive forces limit long-term clinical application. The purpose of this study was to evaluate the attractive force of different types of new-generation magnetic attachment systems. The attractive force of the neodymium-iron-boron (Nd-Fe-B) and samarium-cobalt (Sm-Co) magnetic attachment systems, including closed-field (Hilop and Hicorex) and open-field (Dyna and Steco) systems, was measured in a universal testing machine (n=5). The data were statistically evaluated with 1-way ANOVA and post hoc Tukey-Kramer multiple comparison test (α=.05). The closed-field systems exhibited greater (P<.001) attractive force than the open-field systems. Moreover, there was a statistically significant difference in attractive force between Nd-Fe-B and Sm-Co magnets (P<.001). The strongest attractive force was found with the Hilop system (9.2 N), and the lowest force was found with the Steco system (2.3 N). The new generation of Nd-Fe-B closed-field magnets, along with improved technology, provides sufficient denture retention for clinical application. Copyright © 2011 The Editorial Council of the Journal of Prosthetic Dentistry. Published by Mosby, Inc. All rights reserved.

  6. A markup language for electrocardiogram data acquisition and analysis (ecgML)

    PubMed Central

    Wang, Haiying; Azuaje, Francisco; Jung, Benjamin; Black, Norman

    2003-01-01

    Background The storage and distribution of electrocardiogram data is based on different formats. There is a need to promote the development of standards for their exchange and analysis. Such models should be platform-/ system- and application-independent, flexible and open to every member of the scientific community. Methods A minimum set of information for the representation and storage of electrocardiogram signals has been synthesised from existing recommendations. This specification is encoded into an XML-vocabulary. The model may aid in a flexible exchange and analysis of electrocardiogram information. Results Based on advantages of XML technologies, ecgML has the ability to present a system-, application- and format-independent solution for representation and exchange of electrocardiogram data. The distinction between the proposal developed by the U.S Food and Drug Administration and ecgML model is given. A series of tools, which aim to facilitate ecgML-based applications, are presented. Conclusions The models proposed here can facilitate the generation of a data format, which opens ways for better and clearer interpretation by both humans and machines. Its structured and transparent organisation will allow researchers to expand and test its capabilities in different application domains. The specification and programs for this protocol are publicly available. PMID:12735790

  7. Temporal Code-Driven Stimulation: Definition and Application to Electric Fish Signaling

    PubMed Central

    Lareo, Angel; Forlim, Caroline G.; Pinto, Reynaldo D.; Varona, Pablo; Rodriguez, Francisco de Borja

    2016-01-01

    Closed-loop activity-dependent stimulation is a powerful methodology to assess information processing in biological systems. In this context, the development of novel protocols, their implementation in bioinformatics toolboxes and their application to different description levels open up a wide range of possibilities in the study of biological systems. We developed a methodology for studying biological signals representing them as temporal sequences of binary events. A specific sequence of these events (code) is chosen to deliver a predefined stimulation in a closed-loop manner. The response to this code-driven stimulation can be used to characterize the system. This methodology was implemented in a real time toolbox and tested in the context of electric fish signaling. We show that while there are codes that evoke a response that cannot be distinguished from a control recording without stimulation, other codes evoke a characteristic distinct response. We also compare the code-driven response to open-loop stimulation. The discussed experiments validate the proposed methodology and the software toolbox. PMID:27766078

  8. A semi-implicit augmented IIM for Navier–Stokes equations with open, traction, or free boundary conditions

    PubMed Central

    Li, Zhilin; Xiao, Li; Cai, Qin; Zhao, Hongkai; Luo, Ray

    2016-01-01

    In this paper, a new Navier–Stokes solver based on a finite difference approximation is proposed to solve incompressible flows on irregular domains with open, traction, and free boundary conditions, which can be applied to simulations of fluid structure interaction, implicit solvent model for biomolecular applications and other free boundary or interface problems. For some problems of this type, the projection method and the augmented immersed interface method (IIM) do not work well or does not work at all. The proposed new Navier–Stokes solver is based on the local pressure boundary method, and a semi-implicit augmented IIM. A fast Poisson solver can be used in our algorithm which gives us the potential for developing fast overall solvers in the future. The time discretization is based on a second order multi-step method. Numerical tests with exact solutions are presented to validate the accuracy of the method. Application to fluid structure interaction between an incompressible fluid and a compressible gas bubble is also presented. PMID:27087702

  9. A semi-implicit augmented IIM for Navier-Stokes equations with open, traction, or free boundary conditions.

    PubMed

    Li, Zhilin; Xiao, Li; Cai, Qin; Zhao, Hongkai; Luo, Ray

    2015-08-15

    In this paper, a new Navier-Stokes solver based on a finite difference approximation is proposed to solve incompressible flows on irregular domains with open, traction, and free boundary conditions, which can be applied to simulations of fluid structure interaction, implicit solvent model for biomolecular applications and other free boundary or interface problems. For some problems of this type, the projection method and the augmented immersed interface method (IIM) do not work well or does not work at all. The proposed new Navier-Stokes solver is based on the local pressure boundary method, and a semi-implicit augmented IIM. A fast Poisson solver can be used in our algorithm which gives us the potential for developing fast overall solvers in the future. The time discretization is based on a second order multi-step method. Numerical tests with exact solutions are presented to validate the accuracy of the method. Application to fluid structure interaction between an incompressible fluid and a compressible gas bubble is also presented.

  10. Temporal Code-Driven Stimulation: Definition and Application to Electric Fish Signaling.

    PubMed

    Lareo, Angel; Forlim, Caroline G; Pinto, Reynaldo D; Varona, Pablo; Rodriguez, Francisco de Borja

    2016-01-01

    Closed-loop activity-dependent stimulation is a powerful methodology to assess information processing in biological systems. In this context, the development of novel protocols, their implementation in bioinformatics toolboxes and their application to different description levels open up a wide range of possibilities in the study of biological systems. We developed a methodology for studying biological signals representing them as temporal sequences of binary events. A specific sequence of these events (code) is chosen to deliver a predefined stimulation in a closed-loop manner. The response to this code-driven stimulation can be used to characterize the system. This methodology was implemented in a real time toolbox and tested in the context of electric fish signaling. We show that while there are codes that evoke a response that cannot be distinguished from a control recording without stimulation, other codes evoke a characteristic distinct response. We also compare the code-driven response to open-loop stimulation. The discussed experiments validate the proposed methodology and the software toolbox.

  11. A portable platform for accelerated PIC codes and its application to GPUs using OpenACC

    NASA Astrophysics Data System (ADS)

    Hariri, F.; Tran, T. M.; Jocksch, A.; Lanti, E.; Progsch, J.; Messmer, P.; Brunner, S.; Gheller, C.; Villard, L.

    2016-10-01

    We present a portable platform, called PIC_ENGINE, for accelerating Particle-In-Cell (PIC) codes on heterogeneous many-core architectures such as Graphic Processing Units (GPUs). The aim of this development is efficient simulations on future exascale systems by allowing different parallelization strategies depending on the application problem and the specific architecture. To this end, this platform contains the basic steps of the PIC algorithm and has been designed as a test bed for different algorithmic options and data structures. Among the architectures that this engine can explore, particular attention is given here to systems equipped with GPUs. The study demonstrates that our portable PIC implementation based on the OpenACC programming model can achieve performance closely matching theoretical predictions. Using the Cray XC30 system, Piz Daint, at the Swiss National Supercomputing Centre (CSCS), we show that PIC_ENGINE running on an NVIDIA Kepler K20X GPU can outperform the one on an Intel Sandy bridge 8-core CPU by a factor of 3.4.

  12. Open Source Radiation Hardened by Design Technology

    NASA Technical Reports Server (NTRS)

    Shuler, Robert

    2016-01-01

    The proposed technology allows use of the latest microcircuit technology with lowest power and fastest speed, with minimal delay and engineering costs, through new Radiation Hardened by Design (RHBD) techniques that do not require extensive process characterization, technique evaluation and re-design at each Moore's Law generation. The separation of critical node groups is explicitly parameterized so it can be increased as microcircuit technologies shrink. The technology will be open access to radiation tolerant circuit vendors. INNOVATION: This technology would enhance computation intensive applications such as autonomy, robotics, advanced sensor and tracking processes, as well as low power applications such as wireless sensor networks. OUTCOME / RESULTS: 1) Simulation analysis indicates feasibility. 2)Compact voting latch 65 nanometer test chip designed and submitted for fabrication -7/2016. INFUSION FOR SPACE / EARTH: This technology may be used in any digital integrated circuit in which a high level of resistance to Single Event Upsets is desired, and has the greatest benefit outside low earth orbit where cosmic rays are numerous.

  13. Leveraging OpenStudio's Application Programming Interfaces: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Long, N.; Ball, B.; Goldwasser, D.

    2013-11-01

    OpenStudio development efforts have been focused on providing Application Programming Interfaces (APIs) where users are able to extend OpenStudio without the need to compile the open source libraries. This paper will discuss the basic purposes and functionalities of the core libraries that have been wrapped with APIs including the Building Model, Results Processing, Advanced Analysis, UncertaintyQuantification, and Data Interoperability through Translators. Several building energy modeling applications have been produced using OpenStudio's API and Software Development Kits (SDK) including the United States Department of Energy's Asset ScoreCalculator, a mobile-based audit tool, an energy design assistance reporting protocol, and a portfolio scalemore » incentive optimization analysismethodology. Each of these software applications will be discussed briefly and will describe how the APIs were leveraged for various uses including high-level modeling, data transformations from detailed building audits, error checking/quality assurance of models, and use of high-performance computing for mass simulations.« less

  14. Collaborative development of predictive toxicology applications

    PubMed Central

    2010-01-01

    OpenTox provides an interoperable, standards-based Framework for the support of predictive toxicology data management, algorithms, modelling, validation and reporting. It is relevant to satisfying the chemical safety assessment requirements of the REACH legislation as it supports access to experimental data, (Quantitative) Structure-Activity Relationship models, and toxicological information through an integrating platform that adheres to regulatory requirements and OECD validation principles. Initial research defined the essential components of the Framework including the approach to data access, schema and management, use of controlled vocabularies and ontologies, architecture, web service and communications protocols, and selection and integration of algorithms for predictive modelling. OpenTox provides end-user oriented tools to non-computational specialists, risk assessors, and toxicological experts in addition to Application Programming Interfaces (APIs) for developers of new applications. OpenTox actively supports public standards for data representation, interfaces, vocabularies and ontologies, Open Source approaches to core platform components, and community-based collaboration approaches, so as to progress system interoperability goals. The OpenTox Framework includes APIs and services for compounds, datasets, features, algorithms, models, ontologies, tasks, validation, and reporting which may be combined into multiple applications satisfying a variety of different user needs. OpenTox applications are based on a set of distributed, interoperable OpenTox API-compliant REST web services. The OpenTox approach to ontology allows for efficient mapping of complementary data coming from different datasets into a unifying structure having a shared terminology and representation. Two initial OpenTox applications are presented as an illustration of the potential impact of OpenTox for high-quality and consistent structure-activity relationship modelling of REACH-relevant endpoints: ToxPredict which predicts and reports on toxicities for endpoints for an input chemical structure, and ToxCreate which builds and validates a predictive toxicity model based on an input toxicology dataset. Because of the extensible nature of the standardised Framework design, barriers of interoperability between applications and content are removed, as the user may combine data, models and validation from multiple sources in a dependable and time-effective way. PMID:20807436

  15. Collaborative development of predictive toxicology applications.

    PubMed

    Hardy, Barry; Douglas, Nicki; Helma, Christoph; Rautenberg, Micha; Jeliazkova, Nina; Jeliazkov, Vedrin; Nikolova, Ivelina; Benigni, Romualdo; Tcheremenskaia, Olga; Kramer, Stefan; Girschick, Tobias; Buchwald, Fabian; Wicker, Joerg; Karwath, Andreas; Gütlein, Martin; Maunz, Andreas; Sarimveis, Haralambos; Melagraki, Georgia; Afantitis, Antreas; Sopasakis, Pantelis; Gallagher, David; Poroikov, Vladimir; Filimonov, Dmitry; Zakharov, Alexey; Lagunin, Alexey; Gloriozova, Tatyana; Novikov, Sergey; Skvortsova, Natalia; Druzhilovsky, Dmitry; Chawla, Sunil; Ghosh, Indira; Ray, Surajit; Patel, Hitesh; Escher, Sylvia

    2010-08-31

    OpenTox provides an interoperable, standards-based Framework for the support of predictive toxicology data management, algorithms, modelling, validation and reporting. It is relevant to satisfying the chemical safety assessment requirements of the REACH legislation as it supports access to experimental data, (Quantitative) Structure-Activity Relationship models, and toxicological information through an integrating platform that adheres to regulatory requirements and OECD validation principles. Initial research defined the essential components of the Framework including the approach to data access, schema and management, use of controlled vocabularies and ontologies, architecture, web service and communications protocols, and selection and integration of algorithms for predictive modelling. OpenTox provides end-user oriented tools to non-computational specialists, risk assessors, and toxicological experts in addition to Application Programming Interfaces (APIs) for developers of new applications. OpenTox actively supports public standards for data representation, interfaces, vocabularies and ontologies, Open Source approaches to core platform components, and community-based collaboration approaches, so as to progress system interoperability goals.The OpenTox Framework includes APIs and services for compounds, datasets, features, algorithms, models, ontologies, tasks, validation, and reporting which may be combined into multiple applications satisfying a variety of different user needs. OpenTox applications are based on a set of distributed, interoperable OpenTox API-compliant REST web services. The OpenTox approach to ontology allows for efficient mapping of complementary data coming from different datasets into a unifying structure having a shared terminology and representation.Two initial OpenTox applications are presented as an illustration of the potential impact of OpenTox for high-quality and consistent structure-activity relationship modelling of REACH-relevant endpoints: ToxPredict which predicts and reports on toxicities for endpoints for an input chemical structure, and ToxCreate which builds and validates a predictive toxicity model based on an input toxicology dataset. Because of the extensible nature of the standardised Framework design, barriers of interoperability between applications and content are removed, as the user may combine data, models and validation from multiple sources in a dependable and time-effective way.

  16. 12 CFR 226.51 - Ability to Pay.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) TRUTH IN LENDING (REGULATION Z) Special Rules Applicable to Credit Card Accounts and Open-End Credit... pay. A card issuer must not open a credit card account for a consumer under an open-end (not home-secured) consumer credit plan, or increase any credit limit applicable to such account, unless the card...

  17. 12 CFR 226.51 - Ability to Pay.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ... LENDING (REGULATION Z) Special Rules Applicable to Credit Card Accounts and Open-End Credit Offered to... issuer must not open a credit card account for a consumer under an open-end (not home-secured) consumer credit plan, or increase any credit limit applicable to such account, unless the card issuer considers...

  18. 12 CFR 226.51 - Ability to Pay.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) TRUTH IN LENDING (REGULATION Z) Special Rules Applicable to Credit Card Accounts and Open-End Credit... pay. A card issuer must not open a credit card account for a consumer under an open-end (not home-secured) consumer credit plan, or increase any credit limit applicable to such account, unless the card...

  19. 12 CFR 226.51 - Ability to Pay.

    Code of Federal Regulations, 2011 CFR

    2011-01-01

    ... LENDING (REGULATION Z) Special Rules Applicable to Credit Card Accounts and Open-End Credit Offered to... issuer must not open a credit card account for a consumer under an open-end (not home-secured) consumer credit plan, or increase any credit limit applicable to such account, unless the card issuer considers...

  20. The ALMA common software: dispatch from the trenches

    NASA Astrophysics Data System (ADS)

    Schwarz, J.; Sommer, H.; Jeram, B.; Sekoranja, M.; Chiozzi, G.; Grimstrup, A.; Caproni, A.; Paredes, C.; Allaert, E.; Harrington, S.; Turolla, S.; Cirami, R.

    2008-07-01

    The ALMA Common Software (ACS) provides both an application framework and CORBA-based middleware for the distributed software system of the Atacama Large Millimeter Array. Building upon open-source tools such as the JacORB, TAO and OmniORB ORBs, ACS supports the development of component-based software in any of three languages: Java, C++ and Python. Now in its seventh major release, ACS has matured, both in its feature set as well as in its reliability and performance. However, it is only recently that the ALMA observatory's hardware and application software has reached a level at which it can exploit and challenge the infrastructure that ACS provides. In particular, the availability of an Antenna Test Facility(ATF) at the site of the Very Large Array in New Mexico has enabled us to exercise and test the still evolving end-to-end ALMA software under realistic conditions. The major focus of ACS, consequently, has shifted from the development of new features to consideration of how best to use those that already exist. Configuration details which could be neglected for the purpose of running unit tests or skeletal end-to-end simulations have turned out to be sensitive levers for achieving satisfactory performance in a real-world environment. Surprising behavior in some open-source tools has required us to choose between patching code that we did not write or addressing its deficiencies by implementing workarounds in our own software. We will discuss these and other aspects of our recent experience at the ATF and in simulation.

  1. Strength and stiffness reduction factors for infilled frames with openings

    NASA Astrophysics Data System (ADS)

    Decanini, Luis D.; Liberatore, Laura; Mollaioli, Fabrizio

    2014-09-01

    Framed structures are usually infilled with masonry walls. They may cause a significant increase in both stiffness and strength, reducing the deformation demand and increasing the energy dissipation capacity of the system. On the other hand, irregular arrangements of the masonry panels may lead to the concentration of damage in some regions, with negative effects; for example soft story mechanisms and shear failures in short columns. Therefore, the presence of infill walls should not be neglected, especially in regions of moderate and high seismicity. To this aim, simple models are available for solid infills walls, such as the diagonal no-tension strut model, while infilled frames with openings have not been adequately investigated. In this study, the effect of openings on the strength and stiffness of infilled frames is investigated by means of about 150 experimental and numerical tests. The main parameters involved are identified and a simple model to take into account the openings in the infills is developed and compared with other models proposed by different researchers. The model, which is based on the use of strength and stiffness reduction factors, takes into account the opening dimensions and presence of reinforcing elements around the opening. An example of an application of the proposed reduction factors is also presented.

  2. Testing New Programming Paradigms with NAS Parallel Benchmarks

    NASA Technical Reports Server (NTRS)

    Jin, H.; Frumkin, M.; Schultz, M.; Yan, J.

    2000-01-01

    Over the past decade, high performance computing has evolved rapidly, not only in hardware architectures but also with increasing complexity of real applications. Technologies have been developing to aim at scaling up to thousands of processors on both distributed and shared memory systems. Development of parallel programs on these computers is always a challenging task. Today, writing parallel programs with message passing (e.g. MPI) is the most popular way of achieving scalability and high performance. However, writing message passing programs is difficult and error prone. Recent years new effort has been made in defining new parallel programming paradigms. The best examples are: HPF (based on data parallelism) and OpenMP (based on shared memory parallelism). Both provide simple and clear extensions to sequential programs, thus greatly simplify the tedious tasks encountered in writing message passing programs. HPF is independent of memory hierarchy, however, due to the immaturity of compiler technology its performance is still questionable. Although use of parallel compiler directives is not new, OpenMP offers a portable solution in the shared-memory domain. Another important development involves the tremendous progress in the internet and its associated technology. Although still in its infancy, Java promisses portability in a heterogeneous environment and offers possibility to "compile once and run anywhere." In light of testing these new technologies, we implemented new parallel versions of the NAS Parallel Benchmarks (NPBs) with HPF and OpenMP directives, and extended the work with Java and Java-threads. The purpose of this study is to examine the effectiveness of alternative programming paradigms. NPBs consist of five kernels and three simulated applications that mimic the computation and data movement of large scale computational fluid dynamics (CFD) applications. We started with the serial version included in NPB2.3. Optimization of memory and cache usage was applied to several benchmarks, noticeably BT and SP, resulting in better sequential performance. In order to overcome the lack of an HPF performance model and guide the development of the HPF codes, we employed an empirical performance model for several primitives found in the benchmarks. We encountered a few limitations of HPF, such as lack of supporting the "REDISTRIBUTION" directive and no easy way to handle irregular computation. The parallelization with OpenMP directives was done at the outer-most loop level to achieve the largest granularity. The performance of six HPF and OpenMP benchmarks is compared with their MPI counterparts for the Class-A problem size in the figure in next page. These results were obtained on an SGI Origin2000 (195MHz) with MIPSpro-f77 compiler 7.2.1 for OpenMP and MPI codes and PGI pghpf-2.4.3 compiler with MPI interface for HPF programs.

  3. Strength of SiCf-SiCm composite tube under uniaxial and multiaxial loading

    NASA Astrophysics Data System (ADS)

    Shapovalov, Kirill; Jacobsen, George M.; Alva, Luis; Truesdale, Nathaniel; Deck, Christian P.; Huang, Xinyu

    2018-03-01

    The authors report mechanical strength of nuclear grade silicon carbide fiber reinforced silicon carbide matrix composite (SiCf-SiCm) tubing under several different stress states. The composite tubing was fabricated via a Chemical Vapor Infiltration (CVI) process, and is being evaluated for accident tolerant nuclear fuel cladding. Several experimental techniques were applied including uniaxial tension, elastomer insert burst test, open and closed end hydraulic bladder burst test, and torsion test. These tests provided critical stress and strain values at proportional limit and at ultimate failure points. Full field strain measurements using digital image correlation (DIC) were obtained in order to acquire quantitative information on localized deformation during application of stress. Based on the test results, a failure map was constructed for the SiCf-SiCm composites.

  4. FloorspaceJS - A New, Open Source, Web-Based Geometry Editor for Building Energy Modeling (BEM): Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Macumber, Daniel L; Horowitz, Scott G; Schott, Marjorie

    Across most industries, desktop applications are being rapidly migrated to web applications for a variety of reasons. Web applications are inherently cross platform, mobile, and easier to distribute than desktop applications. Fueling this trend are a wide range of free, open source libraries and frameworks that make it incredibly easy to develop powerful web applications. The building energy modeling community is just beginning to pick up on these larger trends, with a small but growing number of building energy modeling applications starting on or moving to the web. This paper presents a new, open source, web based geometry editor formore » Building Energy Modeling (BEM). The editor is written completely in JavaScript and runs in a modern web browser. The editor works on a custom JSON file format and is designed to be integrated into a variety of web and desktop applications. The web based editor is available to use as a standalone web application at: https://nrel.github.io/openstudio-geometry-editor/. An example integration is demonstrated with the OpenStudio desktop application. Finally, the editor can be easily integrated with a wide range of possible building energy modeling web applications.« less

  5. Enabling Web-Based GIS Tools for Internet and Mobile Devices To Improve and Expand NASA Data Accessibility and Analysis Functionality for the Renewable Energy and Agricultural Applications

    NASA Astrophysics Data System (ADS)

    Ross, A.; Stackhouse, P. W.; Tisdale, B.; Tisdale, M.; Chandler, W.; Hoell, J. M., Jr.; Kusterer, J.

    2014-12-01

    The NASA Langley Research Center Science Directorate and Atmospheric Science Data Center have initiated a pilot program to utilize Geographic Information System (GIS) tools that enable, generate and store climatological averages using spatial queries and calculations in a spatial database resulting in greater accessibility of data for government agencies, industry and private sector individuals. The major objectives of this effort include the 1) Processing and reformulation of current data to be consistent with ESRI and openGIS tools, 2) Develop functions to improve capability and analysis that produce "on-the-fly" data products, extending these past the single location to regional and global scales. 3) Update the current web sites to enable both web-based and mobile application displays for optimization on mobile platforms, 4) Interact with user communities in government and industry to test formats and usage of optimization, and 5) develop a series of metrics that allow for monitoring of progressive performance. Significant project results will include the the development of Open Geospatial Consortium (OGC) compliant web services (WMS, WCS, WFS, WPS) that serve renewable energy and agricultural application products to users using GIS software and tools. Each data product and OGC service will be registered within ECHO, the Common Metadata Repository, the Geospatial Platform, and Data.gov to ensure the data are easily discoverable and provide data users with enhanced access to SSE data, parameters, services, and applications. This effort supports cross agency, cross organization, and interoperability of SSE data products and services by collaborating with DOI, NRCan, NREL, NCAR, and HOMER for requirements vetting and test bed users before making available to the wider public.

  6. Open Rotor Noise Shielding by Blended-Wing-Body Aircraft

    NASA Technical Reports Server (NTRS)

    Guo, Yueping; Czech, Michael J.; Thomas, Russell H.

    2015-01-01

    This paper presents an analysis of open rotor noise shielding by Blended Wing Body (BWB) aircraft by using model scale test data acquired in the Boeing Low Speed Aeroacoustic Facility (LSAF) with a legacy F7/A7 rotor model and a simplified BWB platform. The objective of the analysis is the understanding of the shielding features of the BWB and the method of application of the shielding data for noise studies of BWB aircraft with open rotor propulsion. By studying the directivity patterns of individual tones, it is shown that though the tonal energy distribution and the spectral content of the wind tunnel test model, and thus its total noise, may differ from those of more advanced rotor designs, the individual tones follow directivity patterns that characterize far field radiations of modern open rotors, ensuring the validity of the use of this shielding data. Thus, open rotor tonal noise shielding should be categorized into front rotor tones, aft rotor tones and interaction tones, not only because of the different directivities of the three groups of tones, but also due to the differences in their source locations and coherence features, which make the respective shielding characteristics of the three groups of tones distinctly different from each other. To reveal the parametric trends of the BWB shielding effects, results are presented with variations in frequency, far field emission angle, rotor operational condition, engine installation geometry, and local airframe features. These results prepare the way for the development of parametric models for the shielding effects in prediction tools.

  7. An Open Simulation System Model for Scientific Applications

    NASA Technical Reports Server (NTRS)

    Williams, Anthony D.

    1995-01-01

    A model for a generic and open environment for running multi-code or multi-application simulations - called the open Simulation System Model (OSSM) - is proposed and defined. This model attempts to meet the requirements of complex systems like the Numerical Propulsion Simulator System (NPSS). OSSM places no restrictions on the types of applications that can be integrated at any state of its evolution. This includes applications of different disciplines, fidelities, etc. An implementation strategy is proposed that starts with a basic prototype, and evolves over time to accommodate an increasing number of applications. Potential (standard) software is also identified which may aid in the design and implementation of the system.

  8. Building Automatic Grading Tools for Basic of Programming Lab in an Academic Institution

    NASA Astrophysics Data System (ADS)

    Harimurti, Rina; Iwan Nurhidayat, Andi; Asmunin

    2018-04-01

    The skills of computer programming is a core competency that must be mastered by students majoring in computer sciences. The best way to improve this skill is through the practice of writing many programs to solve various problems from simple to complex. It takes hard work and a long time to check and evaluate the results of student labs one by one, especially if the number of students a lot. Based on these constrain, web proposes Automatic Grading Tools (AGT), the application that can evaluate and deeply check the source code in C, C++. The application architecture consists of students, web-based applications, compilers, and operating systems. Automatic Grading Tools (AGT) is implemented MVC Architecture and using open source software, such as laravel framework version 5.4, PostgreSQL 9.6, Bootstrap 3.3.7, and jquery library. Automatic Grading Tools has also been tested for real problems by submitting source code in C/C++ language and then compiling. The test results show that the AGT application has been running well.

  9. Characterization of multiaxial warp knit composites

    NASA Technical Reports Server (NTRS)

    Dexter, H. Benson; Hasko, Gregory H.; Cano, Roberto J.

    1991-01-01

    The objectives were to characterize the mechanical behavior and damage tolerance of two multiaxial warp knit fabrics to determine the acceptability of these fabrics for high performance composite applications. The tests performed included compression, tension, open hole compression, compression after impact and compression-compression fatigue. Tests were performed on as-fabricated fabrics and on multi-layer fabrics that were stitched together with either carbon or Kevlar stitching yarn. Results of processing studies for vacuum impregnation with Hercules 3501-6 epoxy resin and pressure impregnation with Dow Tactix 138/H41 epoxy resin and British Petroleum BP E905L epoxy resin are presented.

  10. Dynamic stability and handling qualities tests on a highly augmented, statically unstable airplane

    NASA Technical Reports Server (NTRS)

    Gera, Joseph; Bosworth, John T.

    1987-01-01

    Novel flight test and analysis techniques in the flight dynamics and handling qualities area are described. These techniques were utilized at NASA Ames-Dryden during the initial flight envelope clearance of the X-29A aircraft. It is shown that the open-loop frequency response of an aircraft with highly relaxed static stability can be successfully computed on the ground from telemetry data. Postflight closed-loop frequency response data were obtained from pilot-generated frequency sweeps and it is found that the current handling quality requirements for high-maneuverability aircraft are generally applicable to the X-29A.

  11. Influence of stationary components on unsteady flow in industrial centrifugal compressors

    NASA Technical Reports Server (NTRS)

    Bonciani, L.; Terrinoni, L.

    1984-01-01

    An experimental investigation was performed to determine the characteristics of the onset and the growth of rotating nonuniform flow in a standard low specific speed stage, normally utilized in high pressure applications, in relation to change of stationary component geometry. Four configurations, differing only in the return channel and crossover geometry were tested on an atmospheric pressure open loop test rig. Experimental results make conspicious the effect of return channel geometry and give the possibility of shifting the unstable zone onset varying such geometry. An attempt was made to interpret the experimental results in the Emmons - Stenning's rotating stall theory.

  12. Open source machine-learning algorithms for the prediction of optimal cancer drug therapies.

    PubMed

    Huang, Cai; Mezencev, Roman; McDonald, John F; Vannberg, Fredrik

    2017-01-01

    Precision medicine is a rapidly growing area of modern medical science and open source machine-learning codes promise to be a critical component for the successful development of standardized and automated analysis of patient data. One important goal of precision cancer medicine is the accurate prediction of optimal drug therapies from the genomic profiles of individual patient tumors. We introduce here an open source software platform that employs a highly versatile support vector machine (SVM) algorithm combined with a standard recursive feature elimination (RFE) approach to predict personalized drug responses from gene expression profiles. Drug specific models were built using gene expression and drug response data from the National Cancer Institute panel of 60 human cancer cell lines (NCI-60). The models are highly accurate in predicting the drug responsiveness of a variety of cancer cell lines including those comprising the recent NCI-DREAM Challenge. We demonstrate that predictive accuracy is optimized when the learning dataset utilizes all probe-set expression values from a diversity of cancer cell types without pre-filtering for genes generally considered to be "drivers" of cancer onset/progression. Application of our models to publically available ovarian cancer (OC) patient gene expression datasets generated predictions consistent with observed responses previously reported in the literature. By making our algorithm "open source", we hope to facilitate its testing in a variety of cancer types and contexts leading to community-driven improvements and refinements in subsequent applications.

  13. Open-path FTIR data reduction algorithm with atmospheric absorption corrections: the NONLIN code

    NASA Astrophysics Data System (ADS)

    Phillips, William; Russwurm, George M.

    1999-02-01

    This paper describes the progress made to date in developing, testing, and refining a data reduction computer code, NONLIN, that alleviates many of the difficulties experienced in the analysis of open path FTIR data. Among the problems that currently effect FTIR open path data quality are: the inability to obtain a true I degree or background, spectral interferences of atmospheric gases such as water vapor and carbon dioxide, and matching the spectral resolution and shift of the reference spectra to a particular field instrument. This algorithm is based on a non-linear fitting scheme and is therefore not constrained by many of the assumptions required for the application of linear methods such as classical least squares (CLS). As a result, a more realistic mathematical model of the spectral absorption measurement process can be employed in the curve fitting process. Applications of the algorithm have proven successful in circumventing open path data reduction problems. However, recent studies, by one of the authors, of the temperature and pressure effects on atmospheric absorption indicate there exist temperature and water partial pressure effects that should be incorporated into the NONLIN algorithm for accurate quantification of gas concentrations. This paper investigates the sources of these phenomena. As a result of this study a partial pressure correction has been employed in NONLIN computer code. Two typical field spectra are examined to determine what effect the partial pressure correction has on gas quantification.

  14. Performance Comparison of SDN Solutions for Switching Dedicated Long-Haul Connections

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rao, Nageswara S

    2016-01-01

    We consider scenarios with two sites connected over a dedicated, long-haul connection that must quickly fail-over in response to degradations in host-to-host application performance. We present two methods for path fail-over using OpenFlowenabled switches: (a) a light-weight method that utilizes host scripts to monitor the application performance and dpctl API for switching, and (b) a generic method that uses two OpenDaylight (ODL) controllers and REST interfaces. The restoration dynamics of the application contain significant statistical variations due to the controllers, north interfaces and switches; in addition, the variety of vendor implementations further complicates the choice between different solutions. We presentmore » the impulse-response method to estimate the regressions of performance parameters, which enables a rigorous and objective comparison of different solutions. We describe testing results of the two methods, using TCP throughput and connection rtt as main parameters, over a testbed consisting of HP and Cisco switches connected over longhaul connections emulated in hardware by ANUE devices. The combination of analytical and experimental results demonstrates that dpctl method responds seconds faster than ODL method on average, while both methods restore TCP throughput.« less

  15. Corrosion Performance of Fe-Cr-Ni Alloys in Artificial Saliva and Mouthwash Solution

    PubMed Central

    Porcayo-Calderon, J.; Casales-Diaz, M.; Salinas-Bravo, V. M.; Martinez-Gomez, L.

    2015-01-01

    Several austenitic stainless steels suitable for high temperature applications because of their high corrosion resistance and excellent mechanical properties were investigated as biomaterials for dental use. The steels were evaluated by electrochemical techniques such as potentiodynamic polarization curves, cyclic polarization curves, measurements of open circuit potential, and linear polarization resistance. The performance of steels was evaluated in two types of environments: artificial saliva and mouthwash solution at 37°C for 48 hours. In order to compare the behavior of steels, titanium a material commonly used in dental applications was also tested in the same conditions. Results show that tested steels have characteristics that may make them attractive as biomaterials for dental applications. Contents of Cr, Ni, and other minor alloying elements (Mo, Ti, and Nb) determine the performance of stainless steels. In artificial saliva steels show a corrosion rate of the same order of magnitude as titanium and in mouthwash have greater corrosion resistance than titanium. PMID:26064083

  16. High temperature lubricant screening and systems studies

    NASA Technical Reports Server (NTRS)

    Jones, D. A.

    1973-01-01

    Four candidate lubricants for next generation aircraft gas turbine application were tested under open atmosphere conditions in a rig simulating an advanced engine 125 mm bore mainshaft thrust bearing position. Testing was conducted at speeds to 24,000 rpm (3,000,000 bearing DN), bearing ring temperature of 500 F, and with 1200 F air and 100 psi differential pressure across the seals installed in a dual tandem arrangement. Test bearing was a 125 mm bore split inner ring, outer race riding angular contact ball bearing under a 3280 lb. thrust load. One lubricant, a type 2 ester, performed extremely well. The mainshaft seal limited the performance. Numerous design improvements for this seal were indicated.

  17. The impact of new trends in POCTs for companion diagnostics, non-invasive testing and molecular diagnostics.

    PubMed

    Huckle, David

    2015-06-01

    Point-of-care diagnostics have been slowly developing over several decades and have taken on a new importance in current healthcare delivery for both diagnostics and development of new drugs. Molecular diagnostics have become a key driver of technology change and opened up new areas in companion diagnostics for use alongside pharmaceuticals and in new clinical approaches such as non-invasive testing. Future areas involving smartphone and other information technology advances, together with new developments in molecular biology, microfluidics and surface chemistry are adding to advances in the market. The focus for point-of-care tests with molecular diagnostic technologies is focused on advancing effective applications.

  18. A review and analysis of boundary layer transition data for turbine application

    NASA Technical Reports Server (NTRS)

    Gaugler, R. E.

    1984-01-01

    A symposium on transition in turbines was held at the NASA Lewis Research Center. One recommendation of the working groups was the collection of existing transition data to provide standard cases against which models could be tested. A number of data sets from the open literature that include heat transfer data in apparently transitional boundary layers, with particular application to the turbine environment, were reviewed and analyzed to extract transition information from the heat transfer data. The data sets reviewed cover a wide range of flow conditions, from low speed, flat plate tests to full scale turbine airfoils operating at simulated turbine engine conditions. The results indicate that free stream turbulence and pressure gradient have strong, and opposite, effects on the location of the start of transition and on the length of the transition zone.

  19. A review and analysis of boundary layer transition data for turbine application

    NASA Technical Reports Server (NTRS)

    Gaugler, R. E.

    1985-01-01

    A symposium on transition in turbines was held at the NASA Lewis Research Center. One recommendation of the working groups was the collection of existing transition data to provide standard cases against which models could be tested. A number of data sets from the open literature that include heat transfer data in apparently transitional boundary layers, with particular application to the turbine environment, were reviewed and analyzed to extract transition information from the heat transfer data. The data sets reviewed cover a wide range of flow conditions, from low speed, flat plate tests to full scale turbine airfoils operating at simulated turbine engine conditions. The results indicate that free stream turbulence and pressure gradient have strong, and opposite, effects on the location of the start of transition and on the length of the transition zone.

  20. 12 CFR 1026.59 - Reevaluation of rate increases.

    Code of Federal Regulations, 2013 CFR

    2013-01-01

    ...) Special Rules Applicable to Credit Card Accounts and Open-End Credit Offered to College Students § 1026.59... an annual percentage rate that applies to a credit card account under an open-end (not home-secured... percentage rates applicable to similar new credit card accounts under an open-end (not home-secured) consumer...

  1. 12 CFR 1026.59 - Reevaluation of rate increases.

    Code of Federal Regulations, 2012 CFR

    2012-01-01

    ...) Special Rules Applicable to Credit Card Accounts and Open-End Credit Offered to College Students § 1026.59... an annual percentage rate that applies to a credit card account under an open-end (not home-secured... percentage rates applicable to similar new credit card accounts under an open-end (not home-secured) consumer...

  2. 12 CFR 1026.59 - Reevaluation of rate increases.

    Code of Federal Regulations, 2014 CFR

    2014-01-01

    ...) Special Rules Applicable to Credit Card Accounts and Open-End Credit Offered to College Students § 1026.59... an annual percentage rate that applies to a credit card account under an open-end (not home-secured... percentage rates applicable to similar new credit card accounts under an open-end (not home-secured) consumer...

  3. 40 CFR 424.10 - Applicability; description of the open electric furnaces with wet air pollution control devices...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... electric furnaces with wet air pollution control devices subcategory. 424.10 Section 424.10 Protection of... MANUFACTURING POINT SOURCE CATEGORY Open Electric Furnaces With Wet Air Pollution Control Devices Subcategory § 424.10 Applicability; description of the open electric furnaces with wet air pollution control devices...

  4. 40 CFR 424.10 - Applicability; description of the open electric furnaces with wet air pollution control devices...

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... electric furnaces with wet air pollution control devices subcategory. 424.10 Section 424.10 Protection of... MANUFACTURING POINT SOURCE CATEGORY Open Electric Furnaces With Wet Air Pollution Control Devices Subcategory § 424.10 Applicability; description of the open electric furnaces with wet air pollution control devices...

  5. 46 CFR 308.524 - Application for cancellation of Open Cargo Policy, Form MA-304.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... MA-304. 308.524 Section 308.524 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance... application for cancellation of an Open Cargo Policy Form MA-304 may be obtained from the American War Risk...

  6. 46 CFR 308.523 - Application for revision of Open Cargo Policy, Form MA-303.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false Application for revision of Open Cargo Policy, Form MA-303. 308.523 Section 308.523 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Open Policy War Risk Cargo Insurance § 308.523...

  7. 46 CFR 308.524 - Application for cancellation of Open Cargo Policy, Form MA-304.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... MA-304. 308.524 Section 308.524 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance... application for cancellation of an Open Cargo Policy Form MA-304 may be obtained from the American War Risk...

  8. 46 CFR 308.524 - Application for cancellation of Open Cargo Policy, Form MA-304.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... MA-304. 308.524 Section 308.524 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance... application for cancellation of an Open Cargo Policy Form MA-304 may be obtained from the American War Risk...

  9. 46 CFR 308.524 - Application for cancellation of Open Cargo Policy, Form MA-304.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 46 Shipping 8 2014-10-01 2014-10-01 false Application for cancellation of Open Cargo Policy, Form MA-304. 308.524 Section 308.524 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Open Policy War Risk Cargo Insurance § 308...

  10. 46 CFR 308.524 - Application for cancellation of Open Cargo Policy, Form MA-304.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... MA-304. 308.524 Section 308.524 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY OPERATIONS WAR RISK INSURANCE War Risk Cargo Insurance Ii-Open Policy War Risk Cargo Insurance... application for cancellation of an Open Cargo Policy Form MA-304 may be obtained from the American War Risk...

  11. 47 CFR 76.1510 - Application of certain Title VI provisions.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Open Video Systems § 76.1510 Application of certain Title VI provisions. The following sections within part 76 shall also apply to open video systems..., that these sections shall apply to open video systems only to the extent that they do not conflict with...

  12. 47 CFR 76.1510 - Application of certain Title VI provisions.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Open Video Systems § 76.1510 Application of certain Title VI provisions. The following sections within part 76 shall also apply to open video systems..., that these sections shall apply to open video systems only to the extent that they do not conflict with...

  13. 47 CFR 76.1510 - Application of certain Title VI provisions.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Open Video Systems § 76.1510 Application of certain Title VI provisions. The following sections within part 76 shall also apply to open video systems..., that these sections shall apply to open video systems only to the extent that they do not conflict with...

  14. 47 CFR 76.1510 - Application of certain Title VI provisions.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Open Video Systems § 76.1510 Application of certain Title VI provisions. The following sections within part 76 shall also apply to open video systems..., that these sections shall apply to open video systems only to the extent that they do not conflict with...

  15. 47 CFR 76.1510 - Application of certain Title VI provisions.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... SERVICES MULTICHANNEL VIDEO AND CABLE TELEVISION SERVICE Open Video Systems § 76.1510 Application of certain Title VI provisions. The following sections within part 76 shall also apply to open video systems..., that these sections shall apply to open video systems only to the extent that they do not conflict with...

  16. 40 CFR 424.10 - Applicability; description of the open electric furnaces with wet air pollution control devices...

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... electric furnaces with wet air pollution control devices subcategory. 424.10 Section 424.10 Protection of... MANUFACTURING POINT SOURCE CATEGORY Open Electric Furnaces With Wet Air Pollution Control Devices Subcategory § 424.10 Applicability; description of the open electric furnaces with wet air pollution control devices...

  17. 40 CFR 424.10 - Applicability; description of the open electric furnaces with wet air pollution control devices...

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... electric furnaces with wet air pollution control devices subcategory. 424.10 Section 424.10 Protection of... MANUFACTURING POINT SOURCE CATEGORY Open Electric Furnaces With Wet Air Pollution Control Devices Subcategory § 424.10 Applicability; description of the open electric furnaces with wet air pollution control devices...

  18. 40 CFR 424.10 - Applicability; description of the open electric furnaces with wet air pollution control devices...

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... electric furnaces with wet air pollution control devices subcategory. 424.10 Section 424.10 Protection of... MANUFACTURING POINT SOURCE CATEGORY Open Electric Furnaces With Wet Air Pollution Control Devices Subcategory § 424.10 Applicability; description of the open electric furnaces with wet air pollution control devices...

  19. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Barbara Chapman

    OpenMP was not well recognized at the beginning of the project, around year 2003, because of its limited use in DoE production applications and the inmature hardware support for an efficient implementation. Yet in the recent years, it has been graduately adopted both in HPC applications, mostly in the form of MPI+OpenMP hybrid code, and in mid-scale desktop applications for scientific and experimental studies. We have observed this trend and worked deligiently to improve our OpenMP compiler and runtimes, as well as to work with the OpenMP standard organization to make sure OpenMP are evolved in the direction close tomore » DoE missions. In the Center for Programming Models for Scalable Parallel Computing project, the HPCTools team at the University of Houston (UH), directed by Dr. Barbara Chapman, has been working with project partners, external collaborators and hardware vendors to increase the scalability and applicability of OpenMP for multi-core (and future manycore) platforms and for distributed memory systems by exploring different programming models, language extensions, compiler optimizations, as well as runtime library support.« less

  20. Evaluation of CHO Benchmarks on the Arria 10 FPGA using Intel FPGA SDK for OpenCL

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Jin, Zheming; Yoshii, Kazutomo; Finkel, Hal

    The OpenCL standard is an open programming model for accelerating algorithms on heterogeneous computing system. OpenCL extends the C-based programming language for developing portable codes on different platforms such as CPU, Graphics processing units (GPUs), Digital Signal Processors (DSPs) and Field Programmable Gate Arrays (FPGAs). The Intel FPGA SDK for OpenCL is a suite of tools that allows developers to abstract away the complex FPGA-based development flow for a high-level software development flow. Users can focus on the design of hardware-accelerated kernel functions in OpenCL and then direct the tools to generate the low-level FPGA implementations. The approach makes themore » FPGA-based development more accessible to software users as the needs for hybrid computing using CPUs and FPGAs are increasing. It can also significantly reduce the hardware development time as users can evaluate different ideas with high-level language without deep FPGA domain knowledge. Benchmarking of OpenCL-based framework is an effective way for analyzing the performance of system by studying the execution of the benchmark applications. CHO is a suite of benchmark applications that provides support for OpenCL [1]. The authors presented CHO as an OpenCL port of the CHStone benchmark. Using Altera OpenCL (AOCL) compiler to synthesize the benchmark applications, they listed the resource usage and performance of each kernel that can be successfully synthesized by the compiler. In this report, we evaluate the resource usage and performance of the CHO benchmark applications using the Intel FPGA SDK for OpenCL and Nallatech 385A FPGA board that features an Arria 10 FPGA device. The focus of the report is to have a better understanding of the resource usage and performance of the kernel implementations using Arria-10 FPGA devices compared to Stratix-5 FPGA devices. In addition, we also gain knowledge about the limitations of the current compiler when it fails to synthesize a benchmark application.« less

  1. Open source software projects of the caBIG In Vivo Imaging Workspace Software special interest group.

    PubMed

    Prior, Fred W; Erickson, Bradley J; Tarbox, Lawrence

    2007-11-01

    The Cancer Bioinformatics Grid (caBIG) program was created by the National Cancer Institute to facilitate sharing of IT infrastructure, data, and applications among the National Cancer Institute-sponsored cancer research centers. The program was launched in February 2004 and now links more than 50 cancer centers. In April 2005, the In Vivo Imaging Workspace was added to promote the use of imaging in cancer clinical trials. At the inaugural meeting, four special interest groups (SIGs) were established. The Software SIG was charged with identifying projects that focus on open-source software for image visualization and analysis. To date, two projects have been defined by the Software SIG. The eXtensible Imaging Platform project has produced a rapid application development environment that researchers may use to create targeted workflows customized for specific research projects. The Algorithm Validation Tools project will provide a set of tools and data structures that will be used to capture measurement information and associated needed to allow a gold standard to be defined for the given database against which change analysis algorithms can be tested. Through these and future efforts, the caBIG In Vivo Imaging Workspace Software SIG endeavors to advance imaging informatics and provide new open-source software tools to advance cancer research.

  2. Does chlorhexidine prevent dry socket?

    PubMed

    Richards, Derek

    2012-01-01

    The BBO (Bibliografia Brasileira de Odontologia), Biomed Central, Cochrane Library, Directory of Open Access Journals, LILACS, Open-J-Gate, OpenSIGLE, PubMed, Sabinet and Science-Direct databases were searched. Articles were selected for review from the search results on the basis of their compliance with the broad inclusion criteria: relevant to the review question; and prospective two-arm (or more) clinical study. The primary outcome measure was the incidence of AO reported at the patient level. Two reviewers (VY and SM) independently extracted data and assessed the quality of the accepted articles. Individual dichotomous datasets for the control and test group were extracted from each article. Where possible, missing data were calculated from information given in the text or tables. In addition, authors were contacted in order to obtain missing information. Datasets were assessed for their clinical and methodological heterogeneity following Cochrane guidelines. Meta-analysis was conducted with homogeneous datasets. Publication bias was assessed by use of a funnel plot and Egger's regression. Ten randomised trials were included; almost all involved the removal of third molars. Only two of six identified application protocols (single application of chlorhexidine 0.2% gel or multiple application of 0.12% rinse versus placebo) were found to significantly decrease the incidence of AO. Within the limitations of this review, only two of six identified application protocols were found to significantly decrease the incidence of AO. The evidence for both protocols is weak and may be challenged on the grounds of high risk of selection, detection/performance and attrition bias. This systematic review could not identify sufficient evidence supporting the use of chlorhexidine for the prevention of AO. Chlorhexidine seems not to cause any significantly higher adverse reactions than placebo. Future high-quality randomised control trials are needed to provide conclusive evidence on this topic.

  3. Engaging older adults in the visualization of sensor data facilitated by an open platform for connected devices.

    PubMed

    Bock, Christian; Demiris, George; Choi, Yong; Le, Thai; Thompson, Hilaire J; Samuel, Arjmand; Huang, Danny

    2016-03-11

    The use of smart home sensor systems is growing primarily due to the appeal of unobtrusively monitoring older adult health and wellness. However, integrating large-scale sensor systems within residential settings can be challenging when deployment takes place across multiple environments, requiring customization of applications, connection across various devices and effective visualization of complex longitudinal data. The objective of the study was to demonstrate the implementation of a smart home system using an open, extensible platform in a real-world setting and develop an application to visualize data real time. We deployed the open source Lab of Things platform in a house of 11 residents as a demonstration of feasibility over the course of 3 months. The system consisted of Aeon Labs Z-wave Door/Window sensors and an Aeon Labs Multi-sensor that collected data on motion, temperature, luminosity, and humidity. We applied a Rapid Iterative Testing and Evaluation approach towards designing a visualization interface engaging gerontological experts. We then conducted a survey with 19 older adult and caregiver stakeholders to inform further design revisions. Our initial visualization mockups consisted of a bar chart representing activity level over time. Family members felt comfortable using the application. Older adults however, indicated it would be difficult to learn to use the application, and had trouble identifying utility. A key for older adults was ensuring that the data collected could be utilized by their family members, physicians, or caregivers. The approach described in this work is generalizable towards future smart home deployments and can be a valuable guide for researchers to scale a study across multiple homes and connected devices, and to create personalized interfaces for end users.

  4. 42 CFR 84.95 - Service time test; open-circuit apparatus.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 42 Public Health 1 2011-10-01 2011-10-01 false Service time test; open-circuit apparatus. 84.95...-Contained Breathing Apparatus § 84.95 Service time test; open-circuit apparatus. (a) Service time will be measured with a breathing machine as described in § 84.88. (b) The open-circuit apparatus will be...

  5. 42 CFR 84.95 - Service time test; open-circuit apparatus.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Service time test; open-circuit apparatus. 84.95...-Contained Breathing Apparatus § 84.95 Service time test; open-circuit apparatus. (a) Service time will be measured with a breathing machine as described in § 84.88. (b) The open-circuit apparatus will be...

  6. OpenHealth Platform for Interactive Contextualization of Population Health Open Data.

    PubMed

    Almeida, Jonas S; Hajagos, Janos; Crnosija, Ivan; Kurc, Tahsin; Saltz, Mary; Saltz, Joel

    The financial incentives for data science applications leading to improved health outcomes, such as DSRIP (bit.ly/dsrip), are well-aligned with the broad adoption of Open Data by State and Federal agencies. This creates entirely novel opportunities for analytical applications that make exclusive use of the pervasive Web Computing platform. The framework described here explores this new avenue to contextualize Health data in a manner that relies exclusively on the native JavaScript interpreter and data processing resources of the ubiquitous Web Browser. The OpenHealth platform is made publicly available, and is publicly hosted with version control and open source, at https://github.com/mathbiol/openHealth. The different data/analytics workflow architectures explored are accompanied with live applications ranging from DSRIP, such as Hospital Inpatient Prevention Quality Indicators at http://bit.ly/pqiSuffolk, to The Cancer Genome Atlas (TCGA) as illustrated by http://bit.ly/tcgascopeGBM.

  7. Shearography for Non-destructive Inspection with applications to BAT Mask Tile Adhesive Bonding and Specular Surface Honeycomb Panels

    NASA Technical Reports Server (NTRS)

    Lysak, Daniel B.

    2003-01-01

    The applicability of shearography techniques for non-destructive evaluation in two unique application areas is examined. In the first application, shearography is used to evaluate the quality of adhesive bonds holding lead tiles to the B.4T gamma ray mask for the NASA Swift program. Using a vibration excitation, the more poorly bonded tiles are readily identifiable in the shearography image. A quantitative analysis is presented that compares the shearography results with a destructive pull test measuring the force at bond failure. The second application is to evaluate the bonding between the skin and core of a honeycomb structure with a specular (mirror-like) surface. In standard shearography techniques, the object under test must have a diffuse surface to generate the speckle patterns in laser light, which are then sheared. A novel configuration using the specular surface as a mirror to image speckles from a diffuser is presented, opening up the use of shearography to a new class of objects that could not have been examined with the traditional approach. This new technique readily identifies large scale bond failures in the panel, demonstrating the validity of this approach.

  8. GridAPPS-D

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    2017-03-28

    GridAPPS-D is an open-source, open architecture, standards based platform for development of advanced electric power system planning and operations applications. GridAPPS-D provides a documented data abstraction for the application developer enabling creation of applications that can be run in any compliant system or platform. This enables development of applications that are platform vendor independent applications and applications that take advantage of the possibility of data rich and data driven applications based on deployment of smart grid devices and systems.

  9. OpenDA Open Source Generic Data Assimilation Environment and its Application in Process Models

    NASA Astrophysics Data System (ADS)

    El Serafy, Ghada; Verlaan, Martin; Hummel, Stef; Weerts, Albrecht; Dhondia, Juzer

    2010-05-01

    Data Assimilation techniques are essential elements in state-of-the-art development of models and their optimization with data in the field of groundwater, surface water and soil systems. They are essential tools in calibration of complex modelling systems and improvement of model forecasts. The OpenDA is a new and generic open source data assimilation environment for application to a choice of physical process models, applied to case dependent domains. OpenDA was introduced recently when the developers of Costa, an open-source TU Delft project [http://www.costapse.org; Van Velzen and Verlaan; 2007] and those of the DATools from the former WL|Delft Hydraulics [El Serafy et al 2007; Weerts et al. 2009] decided to join forces. OpenDA makes use of a set of interfaces that describe the interaction between models, observations and data assimilation algorithms. It focuses on flexible applications in portable systems for modelling geophysical processes. It provides a generic interfacing protocol that allows combination of the implemented data assimilation techniques with, in principle, any time-stepping model duscribing a process(atmospheric processes, 3D circulation, 2D water level, sea surface temperature, soil systems, groundwater etc.). Presently, OpenDA features filtering techniques and calibration techniques. The presentation will give an overview of the OpenDA and the results of some of its practical applications. Application of data assimilation in portable operational forecasting systems—the DATools assimilation environment, El Serafy G.Y., H. Gerritsen, S. Hummel, A. H. Weerts, A.E. Mynett and M. Tanaka (2007), Journal of Ocean Dynamics, DOI 10.1007/s10236-007-0124-3, pp.485-499. COSTA a problem solving environment for data assimilation applied for hydrodynamical modelling, Van Velzen and Verlaan (2007), Meteorologische Zeitschrift, Volume 16, Number 6, December 2007 , pp. 777-793(17). Application of generic data assimilation tools (DATools) for flood forecasting purposes, A.H. Weerts, G.Y.H. El Serafy, S. Hummel, J. Dhondia, and H. Gerritsen (2009), accepted by Geoscience & Computers.

  10. 78 FR 61350 - Tribal Mobility Fund Phase I Auction (Auction 902); Short-Form Application Filing Window...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2013-10-03

    ... Fund Phase I Auction (Auction 902); Short-Form Application Filing Window Rescheduled To Open on... rescheduling of the filing window for short-form applications and release an updated list of eligible areas for... Application Filing Window Rescheduled To Open on September 30, 2013 1. The Bureaus announce that the filing...

  11. Specification Patent Management for Web Application Platform Ecosystem

    NASA Astrophysics Data System (ADS)

    Fukami, Yoshiaki; Isshiki, Masao; Takeda, Hideaki; Ohmukai, Ikki; Kokuryo, Jiro

    Diversified usage of web applications has encouraged disintegration of web platform into management of identification and applications. Users make use of various kinds of data linked to their identity with multiple applications on certain social web platforms such as Facebook or MySpace. There has emerged competition among web application platforms. Platformers can design relationship with developers by controlling patent of their own specification and adopt open technologies developed external organizations. Platformers choose a way to open according to feature of the specification and their position. Patent management of specification come to be a key success factor to build competitive web application platforms. Each way to attract external developers such as standardization, open source has not discussed and analyzed all together.

  12. Fracture mechanics criteria for turbine engine hot section components

    NASA Technical Reports Server (NTRS)

    Meyers, G. J.

    1982-01-01

    The application of several fracture mechanics data correlation parameters to predicting the crack propagation life of turbine engine hot section components was evaluated. An engine survey was conducted to determine the locations where conventional fracture mechanics approaches may not be adequate to characterize cracking behavior. Both linear and nonlinear fracture mechanics analyses of a cracked annular combustor liner configuration were performed. Isothermal and variable temperature crack propagation tests were performed on Hastelloy X combustor liner material. The crack growth data was reduced using the stress intensity factor, the strain intensity factor, the J integral, crack opening displacement, and Tomkins' model. The parameter which showed the most effectiveness in correlation high temperature and variable temperature Hastelloy X crack growth data was crack opening displacement.

  13. Hydrodynamics of the Certas™ programmable valve for the treatment of hydrocephalus

    PubMed Central

    2012-01-01

    Background The new Certas™ shunt for the treatment of hydrocephalus has seven standard pressure settings that according to the manufacturer range from 36 to 238 mmH2O, and an additional “Virtual Off” setting with an opening pressure >400 mmH2O. Information on actual pressure response and reliability of shunt performance is important in clinical application, especially the “Virtual Off” setting as a non-surgical replacement for shunt ligation. The objective of this study was to evaluate the in-vitro hydrodynamic performance of the Certas™ shunt. Methods Six new Certas™ shunts with proximal and distal catheters were tested with an automated, computerized test system that raised the pressure from zero to a maximum pressure and back to zero at each valve setting. Opening pressure and flow resistance were determined. Results For settings 1–7 the measured opening pressure range was 26 to 247 mmH2O, and the mean change in opening pressure for a one-step adjustment was between 33 and 38 mmH2O. For setting 8 (“Virtual Off”) the measured mean opening pressure was 494 ± 34 mmH2O (range 451 to 556 mmH2O). The mean outflow resistance was 7.0 mmHg/ml/min (outflow conductance 17.9 μl/s/kPa). Conclusions The six shunts had similar characteristics and closely matched the manufacturer’s specifications for opening pressure at settings 1–7. The opening pressure for the “Virtual Off” setting was nearly 500 mmH2O, which is 100 mmH2O higher than the manufacturer’s specification of “>400” and should be functionally off for most patients with communicating hydrocephalus. Clinical studies are needed to evaluate if the CSF dynamic profile persists after implantation in patients. PMID:22643114

  14. Assessing soil erosion risk using RUSLE through a GIS open source desktop and web application.

    PubMed

    Duarte, L; Teodoro, A C; Gonçalves, J A; Soares, D; Cunha, M

    2016-06-01

    Soil erosion is a serious environmental problem. An estimation of the expected soil loss by water-caused erosion can be calculated considering the Revised Universal Soil Loss Equation (RUSLE). Geographical Information Systems (GIS) provide different tools to create categorical maps of soil erosion risk which help to study the risk assessment of soil loss. The objective of this study was to develop a GIS open source application (in QGIS), using the RUSLE methodology for estimating erosion rate at the watershed scale (desktop application) and provide the same application via web access (web application). The applications developed allow one to generate all the maps necessary to evaluate the soil erosion risk. Several libraries and algorithms from SEXTANTE were used to develop these applications. These applications were tested in Montalegre municipality (Portugal). The maps involved in RUSLE method-soil erosivity factor, soil erodibility factor, topographic factor, cover management factor, and support practices-were created. The estimated mean value of the soil loss obtained was 220 ton km(-2) year(-1) ranged from 0.27 to 1283 ton km(-2) year(-1). The results indicated that most of the study area (80 %) is characterized by very low soil erosion level (<321 ton km(-2) year(-1)) and in 4 % of the studied area the soil erosion was higher than 962 ton km(-2) year(-1). It was also concluded that areas with high slope values and bare soil are related with high level of erosion and the higher the P and C values, the higher the soil erosion percentage. The RUSLE web and the desktop application are freely available.

  15. Long-Term Safety of Repeated Blood-Brain Barrier Opening via Focused Ultrasound with Microbubbles in Non-Human Primates Performing a Cognitive Task.

    PubMed

    Downs, Matthew E; Buch, Amanda; Sierra, Carlos; Karakatsani, Maria Eleni; Teichert, Tobias; Chen, Shangshang; Konofagou, Elisa E; Ferrera, Vincent P

    2015-01-01

    Focused Ultrasound (FUS) coupled with intravenous administration of microbubbles (MB) is a non-invasive technique that has been shown to reliably open (increase the permeability of) the blood-brain barrier (BBB) in multiple in vivo models including non-human primates (NHP). This procedure has shown promise for clinical and basic science applications, yet the safety and potential neurological effects of long term application in NHP requires further investigation under parameters shown to be efficacious in that species (500 kHz, 200-400 kPa, 4-5 μm MB, 2 minute sonication). In this study, we repeatedly opened the BBB in the caudate and putamen regions of the basal ganglia of 4 NHP using FUS with systemically-administered MB over 4-20 months. We assessed the safety of the FUS with MB procedure using MRI to detect edema or hemorrhaging in the brain. Contrast enhanced T1-weighted MRI sequences showed a 98% success rate for openings in the targeted regions. T2-weighted and SWI sequences indicated a lack edema in the majority of the cases. We investigated potential neurological effects of the FUS with MB procedure through quantitative cognitive testing of' visual, cognitive, motivational, and motor function using a random dot motion task with reward magnitude bias presented on a touchpanel display. Reaction times during the task significantly increased on the day of the FUS with MB procedure. This increase returned to baseline within 4-5 days after the procedure. Visual motion discrimination thresholds were unaffected. Our results indicate FUS with MB can be a safe method for repeated opening of the BBB at the basal ganglia in NHP for up to 20 months without any long-term negative physiological or neurological effects with the parameters used.

  16. A Review of Gas-Cooled Reactor Concepts for SDI Applications

    DTIC Science & Technology

    1989-08-01

    710 program .) Wire- Core Reactor (proposed by Rockwell). The wire- core reactor utilizes thin fuel wires woven between spacer wires to form an open...reactor is based on results of developmental studies of nuclear rocket propulsion systems. The reactor core is made up of annular fuel assemblies of...XE Addendum to Volume II. NERVA Fuel Development , Westinghouse Astronuclear Laboratory, TNR-230, July 15’ 1972. J I8- Rover Program Reactor Tests

  17. Method for experimental investigation of transient operation on Laval test stand for model size turbines

    NASA Astrophysics Data System (ADS)

    Fraser, R.; Coulaud, M.; Aeschlimann, V.; Lemay, J.; Deschenes, C.

    2016-11-01

    With the growing proportion of inconstant energy source as wind and solar, hydroelectricity becomes a first class source of peak energy in order to regularize the grid. The important increase of start - stop cycles may then cause a premature ageing of runners by both a higher number of cycles in stress fluctuations and by reaching a higher stress level in absolute. Aiming to sustain good quality development on fully homologous scale model turbines, the Hydraulic Machines Laboratory (LAMH) of Laval University has developed a methodology to operate model size turbines on transient regimes such as start-up, stop or load rejection on its test stand. This methodology allows maintaining a constant head while the wicket gates are opening or closing in a representative speed on the model scale of what is made on the prototype. This paper first presents the opening speed on model based on dimensionless numbers, the methodology itself and its application. Then both its limitation and the first results using a bulb turbine are detailed.

  18. Software Defined Networking challenges and future direction: A case study of implementing SDN features on OpenStack private cloud

    NASA Astrophysics Data System (ADS)

    Shamugam, Veeramani; Murray, I.; Leong, J. A.; Sidhu, Amandeep S.

    2016-03-01

    Cloud computing provides services on demand instantly, such as access to network infrastructure consisting of computing hardware, operating systems, network storage, database and applications. Network usage and demands are growing at a very fast rate and to meet the current requirements, there is a need for automatic infrastructure scaling. Traditional networks are difficult to automate because of the distributed nature of their decision making process for switching or routing which are collocated on the same device. Managing complex environments using traditional networks is time-consuming and expensive, especially in the case of generating virtual machines, migration and network configuration. To mitigate the challenges, network operations require efficient, flexible, agile and scalable software defined networks (SDN). This paper discuss various issues in SDN and suggests how to mitigate the network management related issues. A private cloud prototype test bed was setup to implement the SDN on the OpenStack platform to test and evaluate the various network performances provided by the various configurations.

  19. On the Application of Rapid Prototyping Technology for the Fabrication of Flapping Wings for Micro Air Vehicles

    NASA Astrophysics Data System (ADS)

    Kraemer, Kurtis Leigh

    Micro air vehicles (MAV) are a class of small uninhabited aircraft with dimensions less than 15 cm (6 in) and mass less than 500g (1.1 lbs). The aim of this research was to develop a fast, accurate, low-cost, and repeatable fabrication process for flapping MAV wings. Through the use of the RepRap Mendel open-source fused-deposition modeling (FDM) rapid prototyping machine ("3-D printer"), various wing prototypes were designed and fabricated using a bio-inspired approach. Testing of the aerodynamic performance of both real locust wings and the 3-D printed wing prototypes was performed through axial spin testing. Bending stiffness measurements were also performed on the 3-D printed wings. Through the use of open-source rapid prototyping technology, a fast and low-cost fabrication process for flapping MAV wings has been developed, out of which further understanding of flapping wing design and fabrication has been gained.

  20. Development of an Automated DNA Detection System Using an Electrochemical DNA Chip Technology

    NASA Astrophysics Data System (ADS)

    Hongo, Sadato; Okada, Jun; Hashimoto, Koji; Tsuji, Koichi; Nikaido, Masaru; Gemma, Nobuhiro

    A new compact automated DNA detection system Genelyzer™ has been developed. After injecting a sample solution into a cassette with a built-in electrochemical DNA chip, processes from hybridization reaction to detection and analysis are all operated fully automatically. In order to detect a sample DNA, electrical currents from electrodes due to an oxidization reaction of electrochemically active intercalator molecules bound to hybridized DNAs are detected. The intercalator is supplied as a reagent solution by a fluid supply unit of the system. The feasibility test proved that the simultaneous typing of six single nucleotide polymorphisms (SNPs) associated with a rheumatoid arthritis (RA) was carried out within two hours and that all the results were consistent with those by conventional typing methods. It is expected that this system opens a new way to a DNA testing such as a test for infectious diseases, a personalized medicine, a food inspection, a forensic application and any other applications.

  1. 44 CFR 80.13 - Application information.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... ACQUISITION AND RELOCATION FOR OPEN SPACE Requirements Prior to Award § 80.13 Application information. (a) An application for acquisition of property for the purpose of open space must include: (1) A photograph that... deed restriction language, which shall be consistent with the FEMA model deed restriction that the...

  2. 44 CFR 80.13 - Application information.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... ACQUISITION AND RELOCATION FOR OPEN SPACE Requirements Prior to Award § 80.13 Application information. (a) An application for acquisition of property for the purpose of open space must include: (1) A photograph that... deed restriction language, which shall be consistent with the FEMA model deed restriction that the...

  3. 44 CFR 80.13 - Application information.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... ACQUISITION AND RELOCATION FOR OPEN SPACE Requirements Prior to Award § 80.13 Application information. (a) An application for acquisition of property for the purpose of open space must include: (1) A photograph that... deed restriction language, which shall be consistent with the FEMA model deed restriction that the...

  4. Open Scenario Study, Phase II Report: Assessment and Development of Approaches for Satisfying Unclassified Scenario Needs

    DTIC Science & Technology

    2010-01-01

    interface, another providing the application logic (a program used to manipulate the data), and a server running Microsoft SQL Server or Oracle RDBMS... Oracle ) • Mysql (Open Source) • Other What application server software will be needed? • Application Server • CGI PHP/Perl (Open Source...are used throughout DoD and serve a variety of functions. While DoD has a codified and institutionalized process for the development of a common set

  5. Psychophysical investigations of discomfort and disability glare from underground coal mine illumination systems. Open File Report, May 1980-July 1983

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Whitehead, K.L.; Lindahl, P.; Vincent, R.

    1983-10-01

    A literature search was conducted to identify current light-control technology and hardware that may be applicable on underground lighting systems to minimize disability and discomfort glare. No research dealing specifically with mine lighting was found, but abstracts on research considered potentially applicable are included in the report. Information on several commercial light-control products for use in controlling glare are also included. Vision tests conducted on 137 mine personnel to determine their discomfort and disability glare sensitivity indicate their sensitivity to disability glare is about the same as the general population.

  6. Elevated temperature crack growth

    NASA Technical Reports Server (NTRS)

    Yau, J. F.; Malik, S. N.; Kim, K. S.; Vanstone, R. H.; Laflen, J. H.

    1985-01-01

    The objective of the Elevated Temperature Crack Growth Project is to evaluate proposed nonlinear fracture mechanics methods for application to combustor liners of aircraft gas turbine engines. During the first year of this program, proposed path-independent (P-I) integrals were reviewed for such applications. Several P-I integrals were implemented into a finite-element postprocessor which was developed and verified as part of the work. Alloy 718 was selected as the analog material for use in the forthcoming experimental work. A buttonhead, single-edge notch specimen was designed and verified for use in elevated-temperature strain control testing with significant inelastic strains. A crack mouth opening displacement measurement device was developed for further use.

  7. Some failure modes and analysis techniques for terrestrial solar cell modules

    NASA Technical Reports Server (NTRS)

    Shumka, A.; Stern, K. H.

    1978-01-01

    Analysis data are presented on failed/defective silicon solar cell modules of various types and produced by different manufacturers. The failure mode (e.g., internal short and open circuits, output power degradation, isolation resistance degradation, etc.) are discussed in detail and in many cases related to the type of technology used in the manufacture of the modules; wherever applicable, appropriate corrective actions are recommended. Consideration is also given to some failure analysis techniques that are applicable to such modules, including X-ray radiography, capacitance measurement, cell shunt resistance measurement by the shadowing technique, steady-state illumination test station for module performance illumination, laser scanning techniques, and the SEM.

  8. An original architectured NiTi silicone rubber structure for biomedical applications.

    PubMed

    Rey, T; Le Cam, J-B; Chagnon, G; Favier, D; Rebouah, M; Razan, F; Robin, E; Didier, P; Heller, L; Faure, S; Janouchova, K

    2014-12-01

    This paper deals with composite structures for biomedical applications. For this purpose, an architectured tubular structure composed of Nickel Titanium (NiTi) Shape Memory Alloy (SMA) and silicone rubber was fabricated. One of the main interests of such structures is to ensure a good adhesion between its two constitutive materials. A previous study of the authors (Rey et al., 2014) has shown that the adhesion between NiTi and silicone rubber can be improved by an adhesion promoter or plasma treatment. However, adhesion promoters are often not biocompatible. Hence, plasma treatment is favored to be used in the present study. Three different gases were tested; air, argon and oxygen. The effects of these treatments on the maximum force required to pull-out a NiTi wire from the silicone rubber matrix were investigated by means of pull-out tests carried out with a self-developed device. Among the three gases, a higher maximum force was obtained for argon gas in the plasma treatment. A tube shaped architectured NiTi/silicone rubber structure was then produced using this treatment. The composite was tested by means of a bulge test. Results open a new way of investigations for architectured NiTi-silicone structures for biomechanical applications. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Building model analysis applications with the Joint Universal Parameter IdenTification and Evaluation of Reliability (JUPITER) API

    USGS Publications Warehouse

    Banta, E.R.; Hill, M.C.; Poeter, E.; Doherty, J.E.; Babendreier, J.

    2008-01-01

    The open-source, public domain JUPITER (Joint Universal Parameter IdenTification and Evaluation of Reliability) API (Application Programming Interface) provides conventions and Fortran-90 modules to develop applications (computer programs) for analyzing process models. The input and output conventions allow application users to access various applications and the analysis methods they embody with a minimum of time and effort. Process models simulate, for example, physical, chemical, and (or) biological systems of interest using phenomenological, theoretical, or heuristic approaches. The types of model analyses supported by the JUPITER API include, but are not limited to, sensitivity analysis, data needs assessment, calibration, uncertainty analysis, model discrimination, and optimization. The advantages provided by the JUPITER API for users and programmers allow for rapid programming and testing of new ideas. Application-specific coding can be in languages other than the Fortran-90 of the API. This article briefly describes the capabilities and utility of the JUPITER API, lists existing applications, and uses UCODE_2005 as an example.

  10. A survey of quality assurance practices in biomedical open source software projects.

    PubMed

    Koru, Günes; El Emam, Khaled; Neisa, Angelica; Umarji, Medha

    2007-05-07

    Open source (OS) software is continuously gaining recognition and use in the biomedical domain, for example, in health informatics and bioinformatics. Given the mission critical nature of applications in this domain and their potential impact on patient safety, it is important to understand to what degree and how effectively biomedical OS developers perform standard quality assurance (QA) activities such as peer reviews and testing. This would allow the users of biomedical OS software to better understand the quality risks, if any, and the developers to identify process improvement opportunities to produce higher quality software. A survey of developers working on biomedical OS projects was conducted to examine the QA activities that are performed. We took a descriptive approach to summarize the implementation of QA activities and then examined some of the factors that may be related to the implementation of such practices. Our descriptive results show that 63% (95% CI, 54-72) of projects did not include peer reviews in their development process, while 82% (95% CI, 75-89) did include testing. Approximately 74% (95% CI, 67-81) of developers did not have a background in computing, 80% (95% CI, 74-87) were paid for their contributions to the project, and 52% (95% CI, 43-60) had PhDs. A multivariate logistic regression model to predict the implementation of peer reviews was not significant (likelihood ratio test = 16.86, 9 df, P = .051) and neither was a model to predict the implementation of testing (likelihood ratio test = 3.34, 9 df, P = .95). Less attention is paid to peer review than testing. However, the former is a complementary, and necessary, QA practice rather than an alternative. Therefore, one can argue that there are quality risks, at least at this point in time, in transitioning biomedical OS software into any critical settings that may have operational, financial, or safety implications. Developers of biomedical OS applications should invest more effort in implementing systemic peer review practices throughout the development and maintenance processes.

  11. OpenMP 4.5 Validation and Verification Suite

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Pophale, Swaroop S; Bernholdt, David E; Hernandez, Oscar R

    2017-12-15

    OpenMP, a directive-based programming API, introduce directives for accelerator devices that programmers are starting to use more frequently in production codes. To make sure OpenMP directives work correctly across architectures, it is critical to have a mechanism that tests for an implementation's conformance to the OpenMP standard. This testing process can uncover ambiguities in the OpenMP specification, which helps compiler developers and users make a better use of the standard. We fill this gap through our validation and verification test suite that focuses on the offload directives available in OpenMP 4.5.

  12. vitisFlower®: Development and Testing of a Novel Android-Smartphone Application for Assessing the Number of Grapevine Flowers per Inflorescence Using Artificial Vision Techniques

    PubMed Central

    Aquino, Arturo; Millan, Borja; Gaston, Daniel; Diago, María-Paz; Tardaguila, Javier

    2015-01-01

    Grapevine flowering and fruit set greatly determine crop yield. This paper presents a new smartphone application for automatically counting, non-invasively and directly in the vineyard, the flower number in grapevine inflorescence photos by implementing artificial vision techniques. The application, called vitisFlower®, firstly guides the user to appropriately take an inflorescence photo using the smartphone’s camera. Then, by means of image analysis, the flowers in the image are detected and counted. vitisFlower® has been developed for Android devices and uses the OpenCV libraries to maximize computational efficiency. The application was tested on 140 inflorescence images of 11 grapevine varieties taken with two different devices. On average, more than 84% of flowers in the captures were found, with a precision exceeding 94%. Additionally, the application’s efficiency on four different devices covering a wide range of the market’s spectrum was also studied. The results of this benchmarking study showed significant differences among devices, although indicating that the application is efficiently usable even with low-range devices. vitisFlower is one of the first applications for viticulture that is currently freely available on Google Play. PMID:26343664

  13. The NifTK software platform for image-guided interventions: platform overview and NiftyLink messaging.

    PubMed

    Clarkson, Matthew J; Zombori, Gergely; Thompson, Steve; Totz, Johannes; Song, Yi; Espak, Miklos; Johnsen, Stian; Hawkes, David; Ourselin, Sébastien

    2015-03-01

    To perform research in image-guided interventions, researchers need a wide variety of software components, and assembling these components into a flexible and reliable system can be a challenging task. In this paper, the NifTK software platform is presented. A key focus has been high-performance streaming of stereo laparoscopic video data, ultrasound data and tracking data simultaneously. A new messaging library called NiftyLink is introduced that uses the OpenIGTLink protocol and provides the user with easy-to-use asynchronous two-way messaging, high reliability and comprehensive error reporting. A small suite of applications called NiftyGuide has been developed, containing lightweight applications for grabbing data, currently from position trackers and ultrasound scanners. These applications use NiftyLink to stream data into NiftyIGI, which is a workstation-based application, built on top of MITK, for visualisation and user interaction. Design decisions, performance characteristics and initial applications are described in detail. NiftyLink was tested for latency when transmitting images, tracking data, and interleaved imaging and tracking data. NiftyLink can transmit tracking data at 1,024 frames per second (fps) with latency of 0.31 milliseconds, and 512 KB images with latency of 6.06 milliseconds at 32 fps. NiftyIGI was tested, receiving stereo high-definition laparoscopic video at 30 fps, tracking data from 4 rigid bodies at 20-30 fps and ultrasound data at 20 fps with rendering refresh rates between 2 and 20 Hz with no loss of user interaction. These packages form part of the NifTK platform and have proven to be successful in a variety of image-guided surgery projects. Code and documentation for the NifTK platform are available from http://www.niftk.org . NiftyLink is provided open-source under a BSD license and available from http://github.com/NifTK/NiftyLink . The code for this paper is tagged IJCARS-2014.

  14. A novel mobile phone application to assess nutrition environment measures in low- and middle-income countries.

    PubMed

    Kanter, Rebecca; Alvey, Jeniece; Fuentes, Deborah

    2014-09-01

    Consumer nutrition environment measures are important to understanding the food environment, which affects individual dietary intake. A nutrition environment measures survey for supermarkets (NEMS-S) has been designed on paper for use in Guatemala. However, a paper survey is not an inconspicuous data collection method. To design, pilot test, and validate the Guatemala NEMS-S in the form of a mobile phone application (mobile app). CommCare, a free and open-source software application, was used to design the NEMS-S for Guatemala in the form of a mobile app. Two raters tested the mobile app in a single Guatemalan supermarket. Both the interrater and the test-retest reliability of the mobile app were determined using percent agreement and Cohen's kappa score and compared with the interrater and test-retest reliability of the paper version. Interrater reliability was very high between the paper survey and the mobile app (Cohen's kappa > 0.90). Test-retest reliability ranged from kappa 0.78 to 0.91. Between two certified NEMS-S raters, survey completion time using the mobile app was 5 minutes less than that with the paper form (35 vs. 40 minutes). The NEMS-S mobile app provides for more rapid data collection, with equivalent reliability and validity to the NEMS-S paper version, with advantages over a paper-based survey of multiple language capability and concomitant data entry.

  15. Blue guardian: an open architecture for rapid ISR demonstration

    NASA Astrophysics Data System (ADS)

    Barrett, Donald A.; Borntrager, Luke A.; Green, David M.

    2016-05-01

    Throughout the Department of Defense (DoD), acquisition, platform integration, and life cycle costs for weapons systems have continued to rise. Although Open Architecture (OA) interface standards are one of the primary methods being used to reduce these costs, the Air Force Rapid Capabilities Office (AFRCO) has extended the OA concept and chartered the Open Mission System (OMS) initiative with industry to develop and demonstrate a consensus-based, non-proprietary, OA standard for integrating subsystems and services into airborne platforms. The new OMS standard provides the capability to decouple vendor-specific sensors, payloads, and service implementations from platform-specific architectures and is still in the early stages of maturation and demonstration. The Air Force Research Laboratory (AFRL) - Sensors Directorate has developed the Blue Guardian program to demonstrate advanced sensing technology utilizing open architectures in operationally relevant environments. Over the past year, Blue Guardian has developed a platform architecture using the Air Force's OMS reference architecture and conducted a ground and flight test program of multiple payload combinations. Systems tested included a vendor-unique variety of Full Motion Video (FMV) systems, a Wide Area Motion Imagery (WAMI) system, a multi-mode radar system, processing and database functions, multiple decompression algorithms, multiple communications systems, and a suite of software tools. Initial results of the Blue Guardian program show the promise of OA to DoD acquisitions, especially for Intelligence, Surveillance and Reconnaissance (ISR) payload applications. Specifically, the OMS reference architecture was extremely useful in reducing the cost and time required for integrating new systems.

  16. A Discussion of the Effect of Open-Book and Closed-Book Exams on Student Achievement in an Introductory Statistics Course

    ERIC Educational Resources Information Center

    Block, Robert M.

    2012-01-01

    The use of open-book tests, closed-book tests, and notecards on tests in an introductory statistics course is described in this article. A review of the literature shows that open-book assessments are universally recognized to reduce anxiety. The literature is mixed however on whether deeper learning or better preparation occurs with open-book…

  17. Influence of PBL with Open-Book Tests on Knowledge Retention Measured with Progress Tests

    ERIC Educational Resources Information Center

    Heijne-Penninga, M.; Kuks, J. B. M.; Hofman, W. H. A.; Muijtjens, A. M. M.; Cohen-Schotanus, J.

    2013-01-01

    The influence of problem-based learning (PBL) and open-book tests on long-term knowledge retention is unclear and subject of discussion. Hypotheses were that PBL as well as open-book tests positively affect long-term knowledge retention. Four progress test results of fifth and sixth-year medical students (n = 1,648) of three medical schools were…

  18. Regulatory toxicology in the twenty-first century: challenges, perspectives and possible solutions.

    PubMed

    Tralau, Tewes; Oelgeschläger, Michael; Gürtler, Rainer; Heinemeyer, Gerhard; Herzler, Matthias; Höfer, Thomas; Itter, Heike; Kuhl, Thomas; Lange, Nikola; Lorenz, Nicole; Müller-Graf, Christine; Pabel, Ulrike; Pirow, Ralph; Ritz, Vera; Schafft, Helmut; Schneider, Heiko; Schulz, Thomas; Schumacher, David; Zellmer, Sebastian; Fleur-Böl, Gaby; Greiner, Matthias; Lahrssen-Wiederholt, Monika; Lampen, Alfonso; Luch, Andreas; Schönfelder, Gilbert; Solecki, Roland; Wittkowski, Reiner; Hensel, Andreas

    2015-06-01

    The advent of new testing systems and "omics"-technologies has left regulatory toxicology facing one of the biggest challenges for decades. That is the question whether and how these methods can be used for regulatory purposes. The new methods undoubtedly enable regulators to address important open questions of toxicology such as species-specific toxicity, mixture toxicity, low-dose effects, endocrine effects or nanotoxicology, while promising faster and more efficient toxicity testing with the use of less animals. Consequently, the respective assays, methods and testing strategies are subject of several research programs worldwide. On the other hand, the practical application of such tests for regulatory purposes is a matter of ongoing debate. This document summarizes key aspects of this debate in the light of the European "regulatory status quo", while elucidating new perspectives for regulatory toxicity testing.

  19. Evaluation of Oil-Industry Stimulation Practices for Engineered Geothermal Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Peter Van Dyke; Leen Weijers; Ann Robertson-Tait

    Geothermal energy extraction is typically achieved by use of long open-hole intervals in an attempt to connect the well with the greatest possible rock mass. This presents a problem for the development of Enhanced (Engineered) Geothermal Systems (EGS), owing to the challenge of obtaining uniform stimulation throughout the open-hole interval. Fluids are often injected in only a fraction of that interval, reducing heat transfer efficiency and increasing energy cost. Pinnacle Technologies, Inc. and GeothermEx, Inc. evaluated a variety of techniques and methods that are commonly used for hydraulic fracturing of oil and gas wells to increase and evaluate stimulation effectivenessmore » in EGS wells. Headed by Leen Weijers, formerly Manager of Technical Development at Pinnacle Technologies, Inc., the project ran from August 1, 2004 to July 31, 2006 in two one-year periods to address the following tasks and milestones: 1) Analyze stimulation results from the closest oil-field equivalents for EGS applications in the United States (e.g., the Barnett Shale in North Texas) (section 3 on page 8). Pinnacle Technologies, Inc. has collected fracture growth data from thousands of stimulations (section 3.1 on page 12). This data was further evaluated in the context of: a) Identifying techniques best suited to developing a stimulated EGS fracture network (section 3.2 on page 29), and b) quantifying the growth of the network under various conditions to develop a calibrated model for fracture network growth (section 3.3 on page 30). The developed model can be used to design optimized EGS fracture networks that maximize contact with the heat source and minimize short-circuiting (section 3.4 on page 38). 2) Evaluate methods used in oil field applications to improve fluid diversion and penetration and determine their applicability to EGS (section 4 on page 50). These methods include, but are not limited to: a) Stimulation strategies (propped fracturing versus water fracturing versus injecting fluid below fracturing gradients) (section 4.1 on page 50); b) zonal isolation methods (by use of perforated casing or packers) (section 4.2 on page 57); c) fracture re-orientation and fracture network growth techniques (e.g., by use of alternating high- and low-rate injections) (section 4.4 on page 74); and d) fluid diversion methods (by use of the SurgiFrac technique, the StimGun perforation technique, or stress shadowing). This project task is to be completed in the first project year, enabling the most promising techniques to be field tested and evaluated in the second project year. 3) Study the applicability of the methods listed above by utilizing several techniques (section 5 on page 75) including, but not limited to: a) Hydraulic Impedance Testing (HIT) to determine the location of open hydraulic fractures along a open-hole interval; b) pressure transient testing to determine reservoir permeability, pore pressure, and closure stress; and c) treatment well tilt mapping or microseismic mapping to evaluate fracture coverage. These techniques were reviewed for their potential application for EGS in the first project year (section 5.1 on page 75). This study also includes further analysis of any field testing that will be conducted in the Desert Peak area in Nevada for ORMAT Nevada, Inc. (section 5.2 on page 86), with the aim to close the loop to provide reliable calibrated fracture model results. Developed through its hydraulic fracture consulting business, techniques of Pinnacle Technologies, Inc. for stimulating and analyzing fracture growth have helped the oil and gas industry to improve hydraulic fracturing from both a technical and economic perspective. In addition to more than 30 years of experience in the development of geothermal energy for commercial power generation throughout the world, GeothermEx, Inc. brings to the project: 1) Detailed information about specific developed and potential EGS reservoirs, 2) experience with geothermal well design, completion, and testing practices, and 3) a direct connection to the Desert Peak EGS project.« less

  20. OpenSHMEM-UCX : Evaluation of UCX for implementing OpenSHMEM Programming Model

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Baker, Matthew B; Gorentla Venkata, Manjunath; Aderholdt, William Ferrol

    2016-01-01

    The OpenSHMEM reference implementation was developed towards the goal of developing an open source and high-performing Open- SHMEM implementation. To achieve portability and performance across various networks, the OpenSHMEM reference implementation uses GAS- Net and UCCS for network operations. Recently, new network layers have emerged with the promise of providing high-performance, scalabil- ity, and portability for HPC applications. In this paper, we implement the OpenSHMEM reference implementation to use the UCX framework for network operations. Then, we evaluate its performance and scalabil- ity on Cray XK systems to understand UCX s suitability for developing the OpenSHMEM programming model. Further, wemore » develop a bench- mark called SHOMS for evaluating the OpenSHMEM implementation. Our experimental results show that OpenSHMEM-UCX outperforms the vendor supplied OpenSHMEM implementation in most cases on the Cray XK system by up to 40% with respect to message rate and up to 70% for the execution of application kernels.« less

  1. A Study of Clinically Related Open Source Software Projects

    PubMed Central

    Hogarth, Michael A.; Turner, Stuart

    2005-01-01

    Open source software development has recently gained significant interest due to several successful mainstream open source projects. This methodology has been proposed as being similarly viable and beneficial in the clinical application domain as well. However, the clinical software development venue differs significantly from the mainstream software venue. Existing clinical open source projects have not been well characterized nor formally studied so the ‘fit’ of open source in this domain is largely unknown. In order to better understand the open source movement in the clinical application domain, we undertook a study of existing open source clinical projects. In this study we sought to characterize and classify existing clinical open source projects and to determine metrics for their viability. This study revealed several findings which we believe could guide the healthcare community in its quest for successful open source clinical software projects. PMID:16779056

  2. Time-domain seismic modeling in viscoelastic media for full waveform inversion on heterogeneous computing platforms with OpenCL

    NASA Astrophysics Data System (ADS)

    Fabien-Ouellet, Gabriel; Gloaguen, Erwan; Giroux, Bernard

    2017-03-01

    Full Waveform Inversion (FWI) aims at recovering the elastic parameters of the Earth by matching recordings of the ground motion with the direct solution of the wave equation. Modeling the wave propagation for realistic scenarios is computationally intensive, which limits the applicability of FWI. The current hardware evolution brings increasing parallel computing power that can speed up the computations in FWI. However, to take advantage of the diversity of parallel architectures presently available, new programming approaches are required. In this work, we explore the use of OpenCL to develop a portable code that can take advantage of the many parallel processor architectures now available. We present a program called SeisCL for 2D and 3D viscoelastic FWI in the time domain. The code computes the forward and adjoint wavefields using finite-difference and outputs the gradient of the misfit function given by the adjoint state method. To demonstrate the code portability on different architectures, the performance of SeisCL is tested on three different devices: Intel CPUs, NVidia GPUs and Intel Xeon PHI. Results show that the use of GPUs with OpenCL can speed up the computations by nearly two orders of magnitudes over a single threaded application on the CPU. Although OpenCL allows code portability, we show that some device-specific optimization is still required to get the best performance out of a specific architecture. Using OpenCL in conjunction with MPI allows the domain decomposition of large models on several devices located on different nodes of a cluster. For large enough models, the speedup of the domain decomposition varies quasi-linearly with the number of devices. Finally, we investigate two different approaches to compute the gradient by the adjoint state method and show the significant advantages of using OpenCL for FWI.

  3. The Scientific Filesystem

    PubMed Central

    Sochat, Vanessa

    2018-01-01

    Abstract Background Here, we present the Scientific Filesystem (SCIF), an organizational format that supports exposure of executables and metadata for discoverability of scientific applications. The format includes a known filesystem structure, a definition for a set of environment variables describing it, and functions for generation of the variables and interaction with the libraries, metadata, and executables located within. SCIF makes it easy to expose metadata, multiple environments, installation steps, files, and entry points to render scientific applications consistent, modular, and discoverable. A SCIF can be installed on a traditional host or in a container technology such as Docker or Singularity. We start by reviewing the background and rationale for the SCIF, followed by an overview of the specification and the different levels of internal modules (“apps”) that the organizational format affords. Finally, we demonstrate that SCIF is useful by implementing and discussing several use cases that improve user interaction and understanding of scientific applications. SCIF is released along with a client and integration in the Singularity 2.4 software to quickly install and interact with SCIF. When used inside of a reproducible container, a SCIF is a recipe for reproducibility and introspection of the functions and users that it serves. Results We use SCIF to evaluate container software, provide metrics, serve scientific workflows, and execute a primary function under different contexts. To encourage collaboration and sharing of applications, we developed tools along with an open source, version-controlled, tested, and programmatically accessible web infrastructure. SCIF and associated resources are available at https://sci-f.github.io. The ease of using SCIF, especially in the context of containers, offers promise for scientists’ work to be self-documenting and programatically parseable for maximum reproducibility. SCIF opens up an abstraction from underlying programming languages and packaging logic to work with scientific applications, opening up new opportunities for scientific software development. PMID:29718213

  4. Generation of openEHR Test Datasets for Benchmarking.

    PubMed

    El Helou, Samar; Karvonen, Tuukka; Yamamoto, Goshiro; Kume, Naoto; Kobayashi, Shinji; Kondo, Eiji; Hiragi, Shusuke; Okamoto, Kazuya; Tamura, Hiroshi; Kuroda, Tomohiro

    2017-01-01

    openEHR is a widely used EHR specification. Given its technology-independent nature, different approaches for implementing openEHR data repositories exist. Public openEHR datasets are needed to conduct benchmark analyses over different implementations. To address their current unavailability, we propose a method for generating openEHR test datasets that can be publicly shared and used.

  5. Open Source Molecular Modeling

    PubMed Central

    Pirhadi, Somayeh; Sunseri, Jocelyn; Koes, David Ryan

    2016-01-01

    The success of molecular modeling and computational chemistry efforts are, by definition, dependent on quality software applications. Open source software development provides many advantages to users of modeling applications, not the least of which is that the software is free and completely extendable. In this review we categorize, enumerate, and describe available open source software packages for molecular modeling and computational chemistry. PMID:27631126

  6. Adopting Open-Source Software Applications in U. S. Higher Education: A Cross-Disciplinary Review of the Literature

    ERIC Educational Resources Information Center

    van Rooij, Shahron Williams

    2009-01-01

    Higher Education institutions in the United States are considering Open Source software applications such as the Moodle and Sakai course management systems and the Kuali financial system to build integrated learning environments that serve both academic and administrative needs. Open Source is presumed to be more flexible and less costly than…

  7. A feasibility study on porting the community land model onto accelerators using OpenACC

    DOE PAGES

    Wang, Dali; Wu, Wei; Winkler, Frank; ...

    2014-01-01

    As environmental models (such as Accelerated Climate Model for Energy (ACME), Parallel Reactive Flow and Transport Model (PFLOTRAN), Arctic Terrestrial Simulator (ATS), etc.) became more and more complicated, we are facing enormous challenges regarding to porting those applications onto hybrid computing architecture. OpenACC appears as a very promising technology, therefore, we have conducted a feasibility analysis on porting the Community Land Model (CLM), a terrestrial ecosystem model within the Community Earth System Models (CESM)). Specifically, we used automatic function testing platform to extract a small computing kernel out of CLM, then we apply this kernel into the actually CLM dataflowmore » procedure, and investigate the strategy of data parallelization and the benefit of data movement provided by current implementation of OpenACC. Even it is a non-intensive kernel, on a single 16-core computing node, the performance (based on the actual computation time using one GPU) of OpenACC implementation is 2.3 time faster than that of OpenMP implementation using single OpenMP thread, but it is 2.8 times slower than the performance of OpenMP implementation using 16 threads. On multiple nodes, MPI_OpenACC implementation demonstrated very good scalability on up to 128 GPUs on 128 computing nodes. This study also provides useful information for us to look into the potential benefits of “deep copy” capability and “routine” feature of OpenACC standards. In conclusion, we believe that our experience on the environmental model, CLM, can be beneficial to many other scientific research programs who are interested to porting their large scale scientific code using OpenACC onto high-end computers, empowered by hybrid computing architecture.« less

  8. Activate/Inhibit KGCS Gateway via Master Console EIC Pad-B Display

    NASA Technical Reports Server (NTRS)

    Ferreira, Pedro Henrique

    2014-01-01

    My internship consisted of two major projects for the Launch Control System.The purpose of the first project was to implement the Application Control Language (ACL) to Activate Data Acquisition (ADA) and to Inhibit Data Acquisition (IDA) the Kennedy Ground Control Sub-Systems (KGCS) Gateway, to update existing Pad-B End Item Control (EIC) Display to program the ADA and IDA buttons with new ACL, and to test and release the ACL Display.The second project consisted of unit testing all of the Application Services Framework (ASF) by March 21st. The XmlFileReader was unit tested and reached 100 coverage. The XmlFileReader class is used to grab information from XML files and use them to initialize elements in the other framework elements by using the Xerces C++ XML Parser; which is open source commercial off the shelf software. The ScriptThread was also tested. ScriptThread manages the creation and activation of script threads. A large amount of the time was used in initializing the environment and learning how to set up unit tests and getting familiar with the specific segments of the project that were assigned to us.

  9. PubMedPortable: A Framework for Supporting the Development of Text Mining Applications.

    PubMed

    Döring, Kersten; Grüning, Björn A; Telukunta, Kiran K; Thomas, Philippe; Günther, Stefan

    2016-01-01

    Information extraction from biomedical literature is continuously growing in scope and importance. Many tools exist that perform named entity recognition, e.g. of proteins, chemical compounds, and diseases. Furthermore, several approaches deal with the extraction of relations between identified entities. The BioCreative community supports these developments with yearly open challenges, which led to a standardised XML text annotation format called BioC. PubMed provides access to the largest open biomedical literature repository, but there is no unified way of connecting its data to natural language processing tools. Therefore, an appropriate data environment is needed as a basis to combine different software solutions and to develop customised text mining applications. PubMedPortable builds a relational database and a full text index on PubMed citations. It can be applied either to the complete PubMed data set or an arbitrary subset of downloaded PubMed XML files. The software provides the infrastructure to combine stand-alone applications by exporting different data formats, e.g. BioC. The presented workflows show how to use PubMedPortable to retrieve, store, and analyse a disease-specific data set. The provided use cases are well documented in the PubMedPortable wiki. The open-source software library is small, easy to use, and scalable to the user's system requirements. It is freely available for Linux on the web at https://github.com/KerstenDoering/PubMedPortable and for other operating systems as a virtual container. The approach was tested extensively and applied successfully in several projects.

  10. PubMedPortable: A Framework for Supporting the Development of Text Mining Applications

    PubMed Central

    Döring, Kersten; Grüning, Björn A.; Telukunta, Kiran K.; Thomas, Philippe; Günther, Stefan

    2016-01-01

    Information extraction from biomedical literature is continuously growing in scope and importance. Many tools exist that perform named entity recognition, e.g. of proteins, chemical compounds, and diseases. Furthermore, several approaches deal with the extraction of relations between identified entities. The BioCreative community supports these developments with yearly open challenges, which led to a standardised XML text annotation format called BioC. PubMed provides access to the largest open biomedical literature repository, but there is no unified way of connecting its data to natural language processing tools. Therefore, an appropriate data environment is needed as a basis to combine different software solutions and to develop customised text mining applications. PubMedPortable builds a relational database and a full text index on PubMed citations. It can be applied either to the complete PubMed data set or an arbitrary subset of downloaded PubMed XML files. The software provides the infrastructure to combine stand-alone applications by exporting different data formats, e.g. BioC. The presented workflows show how to use PubMedPortable to retrieve, store, and analyse a disease-specific data set. The provided use cases are well documented in the PubMedPortable wiki. The open-source software library is small, easy to use, and scalable to the user’s system requirements. It is freely available for Linux on the web at https://github.com/KerstenDoering/PubMedPortable and for other operating systems as a virtual container. The approach was tested extensively and applied successfully in several projects. PMID:27706202

  11. Laser Beam Welding of Ultra-high Strength Chromium Steel with Martensitic Microstructure

    NASA Astrophysics Data System (ADS)

    Dahmen, Martin; Janzen, Vitalij; Lindner, Stefan; Wagener, Rainer

    A new class of steels is going to be introduced into sheet manufacturing. Stainless ferritic and martensitic steels open up opportunities for sheet metal fabrication including hot stamping. Strengths of up to 2 GPa at fracture elongations of 15% can be attained through this. Welding of these materials, as a result, became a challenge. Energy-reduced welding methods with in-situ heat treatment are required in order to ensure the delicate and complex heat control. Laser beam welding is the joining technique of choice to supply minimum heat input to the fusion process and to apply efficient heat control. For two application cases, tailored blank production in as-rolled condition and welding during assembly in hot stamped condition, welding processes have been developed. The welding suitability is shown through metallurgical investigations of the welds. Crash tests based on the KS-II concept as well as fatigue tests prove the applicability of the joining method.

  12. Safety Aspects of Bio-Based Nanomaterials.

    PubMed

    Catalán, Julia; Norppa, Hannu

    2017-12-01

    Moving towards a bio-based and circular economy implies a major focus on the responsible and sustainable utilization of bio-resources. The emergence of nanotechnology has opened multiple possibilities, not only in the existing industrial sectors, but also for completely novel applications of nanoscale bio-materials, the commercial exploitation of which has only begun during the last few years. Bio-based materials are often assumed not to be toxic. However, this pre-assumption is not necessarily true. Here, we provide a short overview on health and environmental aspects associated with bio-based nanomaterials, and on the relevant regulatory requirements. We also discuss testing strategies that may be used for screening purposes at pre-commercial stages. Although the tests presently used to reveal hazards are still evolving, regarding modifi-cations required for nanomaterials, their application is needed before the upscaling or commercialization of bio-based nanomaterials, to ensure the market potential of the nanomaterials is not delayed by uncertainties about safety issues.

  13. Characterization of UMT2013 Performance on Advanced Architectures

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Howell, Louis

    2014-12-31

    This paper presents part of a larger effort to make detailed assessments of several proxy applications on various advanced architectures, with the eventual goal of extending these assessments to codes of programmatic interest running more realistic simulations. The focus here is on UMT2013, a proxy implementation of deterministic transport for unstructured meshes. I present weak and strong MPI scaling results and studies of OpenMP efficiency on the Sequoia BG/Q system at LLNL, with comparison against similar tests on an Intel Sandy Bridge TLCC2 system. The hardware counters on BG/Q provide detailed information on many aspects of on-node performance, while informationmore » from the mpiP tool gives insight into the reasons for the differing scaling behavior on these two different architectures. Preliminary tests that exploit NVRAM as extended memory on an Ivy Bridge machine designed for “Big Data” applications are also included.« less

  14. A review and analysis of boundary layer transition data for turbine application

    NASA Technical Reports Server (NTRS)

    Gaugler, R. E.

    1985-01-01

    A number of data sets from the open literature that include heat transfer data in apparently transitional boundary layers, with particular application to the turbine environment, were reviewed and analyzed to extract transition information. The data were analyzed by using a version of the STAN5 two-dimensional boundary layer code. The transition starting and ending points were determined by adjusting parameters in STAN5 until the calculations matched the data. The results are presented as a table of the deduced transition location and length as functions of the test parameters. The data sets reviewed cover a wide range of flow conditions, from low-speed, flat-plate tests to full-scale turbine airfoils operating at simulated turbine engine conditions. The results indicate that free-stream turbulence and pressure gradient have strong, and opposite, effects on the location of the start of transition and on the length of the transition zone.

  15. The Grass Isn’t Always Greener: Perceptions of and Performance on Open-Note Exams

    PubMed Central

    Sato, Brian K.; He, Wenliang; Warschauer, Mark; Kadandale, Pavan

    2015-01-01

    Undergraduate biology education is often viewed as being focused on memorization rather than development of students’ critical-thinking abilities. We speculated that open-note testing would be an easily implemented change that would emphasize higher-order thinking. As open-note testing is not commonly used in the biological sciences and the literature on its effects in biology education is sparse, we performed a comprehensive analysis of this intervention on a primary literature–based exam across three large-enrollment laboratory courses. Although students believed open-note testing would impact exam scores, we found no effect on performance, either overall or on questions of nearly all Bloom’s levels. Open-note testing also produced no advantage when examined under a variety of parameters, including research experience, grade point average, course grade, prior exposure to primary literature–focused laboratory courses, or gender. Interestingly, we did observe small differences in open- and closed-note exam performance and perception for students who experienced open-note exams for an entire quarter. This implies that student preparation or in-test behavior can be altered by exposure to open-note testing conditions in a single course and that ­increased experience may be necessary to truly understand the impact of this intervention. PMID:25828402

  16. Rapid development of medical imaging tools with open-source libraries.

    PubMed

    Caban, Jesus J; Joshi, Alark; Nagy, Paul

    2007-11-01

    Rapid prototyping is an important element in researching new imaging analysis techniques and developing custom medical applications. In the last ten years, the open source community and the number of open source libraries and freely available frameworks for biomedical research have grown significantly. What they offer are now considered standards in medical image analysis, computer-aided diagnosis, and medical visualization. A cursory review of the peer-reviewed literature in imaging informatics (indeed, in almost any information technology-dependent scientific discipline) indicates the current reliance on open source libraries to accelerate development and validation of processes and techniques. In this survey paper, we review and compare a few of the most successful open source libraries and frameworks for medical application development. Our dual intentions are to provide evidence that these approaches already constitute a vital and essential part of medical image analysis, diagnosis, and visualization and to motivate the reader to use open source libraries and software for rapid prototyping of medical applications and tools.

  17. Fault tolerant system based on IDDQ testing

    NASA Astrophysics Data System (ADS)

    Guibane, Badi; Hamdi, Belgacem; Mtibaa, Abdellatif; Bensalem, Brahim

    2018-06-01

    Offline test is essential to ensure good manufacturing quality. However, for permanent or transient faults that occur during the use of the integrated circuit in an application, an online integrated test is needed as well. This procedure should ensure the detection and possibly the correction or the masking of these faults. This requirement of self-correction is sometimes necessary, especially in critical applications that require high security such as automotive, space or biomedical applications. We propose a fault-tolerant design for analogue and mixed-signal design complementary metal oxide (CMOS) circuits based on the quiescent current supply (IDDQ) testing. A defect can cause an increase in current consumption. IDDQ testing technique is based on the measurement of power supply current to distinguish between functional and failed circuits. The technique has been an effective testing method for detecting physical defects such as gate-oxide shorts, floating gates (open) and bridging defects in CMOS integrated circuits. An architecture called BICS (Built In Current Sensor) is used for monitoring the supply current (IDDQ) of the connected integrated circuit. If the measured current is not within the normal range, a defect is signalled and the system switches connection from the defective to a functional integrated circuit. The fault-tolerant technique is composed essentially by a double mirror built-in current sensor, allowing the detection of abnormal current consumption and blocks allowing the connection to redundant circuits, if a defect occurs. Spices simulations are performed to valid the proposed design.

  18. Design of a Synthetic Aperture Array to Support Experiments in Active Control of Scattering

    DTIC Science & Technology

    1990-06-01

    becomes necessary to validate the theory and test the control system algorithms . While experiments in open water would be most like the anticipated...mathematical development of the beamforming algorithms used as well as an estimate of their applicability to the specifics of beamforming in a reverberant...Chebyshev array have been proposed. The method used in ARRAY, a nested product algorithm , proposed by Bresler [21] is recommended by Pozar [19] and

  19. Generalized Intelligent Framework for Tutoring (GIFT) Cloud/Virtual Open Campus Quick-Start Guide

    DTIC Science & Technology

    2016-03-01

    distribution is unlimited. 13. SUPPLEMENTARY NOTES 14. ABSTRACT This document serves as the quick-start guide for GIFT Cloud, the web -based...to users with a GIFT Account at no cost. GIFT Cloud is a new implementation of GIFT. This web -based application allows learners, authors, and...distribution is unlimited. 3 3. Requirements for GIFT Cloud GIFT Cloud is accessed via a web browser. Officially, GIFT Cloud has been tested to work on

  20. Copper-palladium core-shell as an anode in a multi-fuel membraneless nanofluidic fuel cell: toward a new era of small energy conversion devices.

    PubMed

    Maya-Cornejo, J; Ortiz-Ortega, E; Álvarez-Contreras, L; Arjona, N; Guerra-Balcázar, M; Ledesma-García, J; Arriaga, L G

    2015-02-14

    A membraneless nanofluidic fuel cell with flow-through electrodes that works with several fuels (individually or mixed): methanol, ethanol, glycerol and ethylene-glycol in alkaline media is presented. For this application, an efficient Cu@Pd electrocatalyst was synthesized and tested, resulting outstanding performance until now reported, opening the possibility of power nano-devices for multi-uses purposes, regardless of fuel re-charge employed.

  1. High Rate Lithium-Thionyl Chloride Battery Development for Undersea Weapon Propulsion Applications. Revised.

    DTIC Science & Technology

    1978-08-23

    dislodged only a fraction of the SAB. According to FMI, thinner, more open grades of vitreous carbon paper would permit higher loading of SAB...bonded carbon fiber, porous silver and porous nickel cathodes were dis- charged in test cells. All polarized immediately below 2. 7 volts at 52 mA/cm2...Increased electrolyte molarity delivered a modest increase in run time but resulted -_ in somewhat lower load voltage plateaus. - As before, carbon fiber

  2. Cloud Environment Automation: from infrastructure deployment to application monitoring

    NASA Astrophysics Data System (ADS)

    Aiftimiei, C.; Costantini, A.; Bucchi, R.; Italiano, A.; Michelotto, D.; Panella, M.; Pergolesi, M.; Saletta, M.; Traldi, S.; Vistoli, C.; Zizzi, G.; Salomoni, D.

    2017-10-01

    The potential offered by the cloud paradigm is often limited by technical issues, rules and regulations. In particular, the activities related to the design and deployment of the Infrastructure as a Service (IaaS) cloud layer can be difficult to apply and time-consuming for the infrastructure maintainers. In this paper the research activity, carried out during the Open City Platform (OCP) research project [1], aimed at designing and developing an automatic tool for cloud-based IaaS deployment is presented. Open City Platform is an industrial research project funded by the Italian Ministry of University and Research (MIUR), started in 2014. It intends to research, develop and test new technological solutions open, interoperable and usable on-demand in the field of Cloud Computing, along with new sustainable organizational models that can be deployed for and adopted by the Public Administrations (PA). The presented work and the related outcomes are aimed at simplifying the deployment and maintenance of a complete IaaS cloud-based infrastructure.

  3. [Application of high frequency electric welding in adrenal surgery. Current state and prospects].

    PubMed

    Kvacheniuk, A N; Suprun, I S; Negrienko, K V; Barenfel'd, A I; Datta, M R; Datta, L R; Nelep, A D

    2012-07-01

    In 14 patients underwent open adrenalectomy with high-frequency electric welding application (I group), in 8 - open adrenalectomy (II group). The two groups were compared: duration of surgery, blood loss, postoperative pain intensity, duration of postoperative hospitalization, the frequency of intra-and postoperative complications, histological changes in tissues. The advantages of open adrenalectomy with high-frequency electric welding application feel less duration of surgery and estimated blood loss, lack of necrosis in the surrounding tissues and foreign bodies in the wound, reducing the trauma of surgery, improving rehabilitation.

  4. Medical school admission test: advantages for students whose parents are medical doctors?

    PubMed

    Simmenroth-Nayda, Anne; Görlich, Yvonne

    2015-04-23

    Admission candidates especially in medicine do not represent the socio-demographic proportions of the average population: children of parents with an academic background are highly overrepresented, and those with parents who are medical doctors represent quite a large and special group. At Göttingen University Medicine, a new admission procedure was established with the intention to broaden the base of applicants towards including candidates with previous medical training or lower final school grades. With a view to family background, we wished to know whether candidates differ in the test scores in our admission procedure. In February 2014 we asked all admission candidates of Göttingen University Medicine by questionnaire (nine closed, four open questions) about the academic background in their families, specifically, the medical background, school exam grades, and previous medical training as well as about how they prepared for the admission test. We also analysed data from admission scores of this group (semi-structured interview and four multiple mini-interviews). In addition to descriptive statistics, we used a Pearson correlation, means comparisons (t-test, analysis of variance), ANOVA, and a Scheffé test. In February 2014 nearly half of the applicants (44%) at Göttingen University Medicine had a medical background, most frequently, their parents were physicians. This rate is much higher than reported in the literature. Other socio-demographic baseline data did not differ from the percentages given in the literature. Of all applicants, 20% had previous medical training. The group of applicants with parents who were medical doctors did not show any advantage in either test-scoring (MMI and interview), their individual preparation for the admission test, or in receiving or accepting a place at medical school. Candidates with parents who were medical doctors had scored slightly lower in school exam grades. Our results suggest that there is a self-selection bias as well as a pre-selection for this particular group of applicants. This effect has to be observed during future admission procedures.

  5. Design and development of a large diameter high pressure fast acting propulsion valve and valve actuator

    NASA Technical Reports Server (NTRS)

    Srinivasan, K. V.

    1986-01-01

    The design and development of a large diameter high pressure quick acting propulsion valve and valve actuator is described. The valve is the heart of a major test facility dedicated to conducting full scale performance tests of aircraft landing systems. The valve opens in less than 300 milliseconds releasing a 46-centimeter- (18-in.-) diameter water jet and closes in 300 milliseconds. The four main components of the valve, i.e., valve body, safety shutter, high speed shutter, and pneumatic-hydraulic actuator, are discussed. This valve is unique and may have other aerospace and industrial applications.

  6. Design and Development of a Large Diameter, High Pressure, Fast Acting Propulsion Valve and Valve Actuator

    NASA Technical Reports Server (NTRS)

    Srinivasan, K. V.

    1986-01-01

    This paper describes the design and development of a large diameter high pressure quick acting propulsion valve and valve actuator. The valve is the heart of a major test facility dedicated to conducting full scale performance tests of aircraft landing gear systems. The valve opens in less than 300 milliseconds releasing a 46 cm (18 in) diameter water jet and closes in 300 milliseconds. The four main components of the valve, i.e., valve body, safety shutter, high speed shutter, and pneumatic-hydraulic actuator, are discussed. This valve is unique and may have other aerospace and industrial applications.

  7. Posttest analysis of MIST Test 330302 using TRAC-PF1/MOD1

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Boyack, B E

    This report discusses a posttest analysis of Multi-Loop Integral System Test (MIST) 330302 which has been performed using TRAC-PF1/MOD1. This test was one of group performed in the MIST facility to investigate high-pressure injection (HPI)-power-operated relief valve (PORV) cooling, also known as feed-and-bleed cooling. In Test 330302, HPI cooling was delayed 20 min after opening and locking the PORV open to induce extensive system voiding. We have concluded that the TRAC-calculated results are in reasonable overall agreement with the data for Test 330302. All major trends and phenomena were correctly predicted. Differences observed between the measured and calculated results havemore » been traced and related, in part, to deficiencies in our knowledge of the facility configuration and operation. We have identified two models forwhich additional review is appropriate. However, in general, the TRAC closure models and correlations appear to be adequate for the prediction of the phenomena expected to occur during feed-and-bleed transientsin the MIST facility. We believe that the correct conclusions about trends and phenomena will be reached if the code is used in similar applications. Conclusions reached regarding use of the code to calculate similar phenomena in full-size plants (scaling implications) and regulatory implications of this work are also presented.« less

  8. Multi-board kernel communication using socket programming for embedded applications

    NASA Astrophysics Data System (ADS)

    Mishra, Ashish; Girdhar, Neha; Krishnia, Nikita

    2016-03-01

    It is often seen in large application projects, there is a need to communicate between two different processors or two different kernels. The aim of this paper is to communicate between two different kernels and use efficient method to do so. The TCP/IP protocol is implemented to communicate between two boards via the Ethernet port and use lwIP (lightweight IP) stack, which is a smaller independent implementation of the TCP/IP stack suitable for use in embedded systems. While retaining TCP/IP functionality, lwIP stack reduces the use of memory and even size of the code. In this process of communication we made Raspberry pi as an active client and Field programmable gate array(FPGA) board as a passive server and they are allowed to communicate via Ethernet. Three applications based on TCP/IP client-server network communication have been implemented. The Echo server application is used to communicate between two different kernels of two different boards. Socket programming is used as it is independent of platform and programming language used. TCP transmit and receive throughput test applications are used to measure maximum throughput of the transmission of data. These applications are based on communication to an open source tool called iperf. It is used to measure the throughput transmission rate by sending or receiving some constant piece of data to the client or server according to the test application.

  9. Integrating open-source software applications to build molecular dynamics systems.

    PubMed

    Allen, Bruce M; Predecki, Paul K; Kumosa, Maciej

    2014-04-05

    Three open-source applications, NanoEngineer-1, packmol, and mis2lmp are integrated using an open-source file format to quickly create molecular dynamics (MD) cells for simulation. The three software applications collectively make up the open-source software (OSS) suite known as MD Studio (MDS). The software is validated through software engineering practices and is verified through simulation of the diglycidyl ether of bisphenol-a and isophorone diamine (DGEBA/IPD) system. Multiple simulations are run using the MDS software to create MD cells, and the data generated are used to calculate density, bulk modulus, and glass transition temperature of the DGEBA/IPD system. Simulation results compare well with published experimental and numerical results. The MDS software prototype confirms that OSS applications can be analyzed against real-world research requirements and integrated to create a new capability. Copyright © 2014 Wiley Periodicals, Inc.

  10. Mapping urban green open space in Bontang city using QGIS and cloud computing

    NASA Astrophysics Data System (ADS)

    Agus, F.; Ramadiani; Silalahi, W.; Armanda, A.; Kusnandar

    2018-04-01

    Digital mapping techniques are available freely and openly so that map-based application development is easier, faster and cheaper. A rapid development of Cloud Computing Geographic Information System makes this system can help the needs of the community for the provision of geospatial information online. The presence of urban Green Open Space (GOS) provide great benefits as an oxygen supplier, carbon-binding agent and can contribute to providing comfort and beauty of city life. This study aims to propose a platform application of GIS Cloud Computing (CC) of Bontang City GOS mapping. The GIS-CC platform uses the basic map available that’s free and open source. The research used survey method to collect GOS data obtained from Bontang City Government, while application developing works Quantum GIS-CC. The result section describes the existence of GOS Bontang City and the design of GOS mapping application.

  11. Evaluation of electrical test conditions in MIL-M-38510 slash sheets

    NASA Astrophysics Data System (ADS)

    Sandgren, K.

    1980-08-01

    Adequacy of MIL-M-38510 slash sheet requirements for electrical test conditions in an automated test environment were evaluated. Military temperature range commercial devices of 13 types from 6 manufacturers were purchased. Software for testing these devices and for varying the test conditions was written for the Tektronix S-3260 test system. The devices were tested to evaluate the effects of pin-condition settling time, measurement sequence of the same and different D-C parameters, temperature sequence, differently defined temperature ambients, variable measurement conditions, sequence of time measurements, pin-application sequence, and undesignated pin condition ambiguity. An alternative to current tri-state enable and disable time measurements is proposed; S-3260 'open' and 'ground' conditions are characterized; and suggestions for changes in MIL-M-38510 slash sheet specifications and MIL-STD-883 test methods are proposed, both to correct errors and ambiguities and to facilitate the gathering of repeatable data on automated test equipment. Data obtained showed no sensitivity to measurement or temperature sequence nor to temperature ambient, provided that test times were not excessive. V sub ICP tests and some low current measurements required allowance for a pin condition settling time because of the test system speed. Some pin condition application sequences yielded incorrect measurements. Undefined terminal conditions of output pins were found to affect I sub OS and propagation delay time measurements. Truth table test results varied with test frequency and V sub IL for low-power Schottky devices.

  12. Spatializing Open Data for the Assessment and the Improvement of Territorial and Social Cohesion

    NASA Astrophysics Data System (ADS)

    Scorza, F.; Las Casas, G. B.; Murgante, B.

    2016-09-01

    An integrated place-based approach for the improvement of territorial and social cohesion is the new instance for planning disciplines, coming from EU New Cohesion Policies. This paper considers the territorial impact assessment of regional development policies as a precondition in order to develop balanced and effective operative programs at national and regional levels. The contribution of `open data' appears to be mature in order to support this application and in this paper we present a spatial analysis technique for the evaluation of EU funds effects at territorial level, starting from open data by Open Cohesion. The application is focused on internal areas of Basilicata Region: Agri river Valley. A complex contest, where environmental and agricultural traditional vocations conflict with a recent development of oil extraction industries. Conclusions concern further applications and perspectives to improve and support regional development planning considering the exploitation of open data sources and spatial analysis.

  13. Common Approach to Geoprocessing of Uav Data across Application Domains

    NASA Astrophysics Data System (ADS)

    Percivall, G. S.; Reichardt, M.; Taylor, T.

    2015-08-01

    UAVs are a disruptive technology bringing new geographic data and information to many application domains. UASs are similar to other geographic imagery systems so existing frameworks are applicable. But the diversity of UAVs as platforms along with the diversity of available sensors are presenting challenges in the processing and creation of geospatial products. Efficient processing and dissemination of the data is achieved using software and systems that implement open standards. The challenges identified point to the need for use of existing standards and extending standards. Results from the use of the OGC Sensor Web Enablement set of standards are presented. Next steps in the progress of UAVs and UASs may follow the path of open data, open source and open standards.

  14. Electrically reversible cracks in an intermetallic film controlled by an electric field

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Liu, Z. Q.; Liu, J. H.; Biegalski, M. D.

    Cracks in solid-state materials are typically irreversible. We report electrically reversible opening and closing of nanoscale cracks in an intermetallic thin film grown on a ferroelectric substrate driven by a small electric field (~0.83 kV/cm). Accordingly, a nonvolatile colossal electroresistance on-off ratio of more than 10 8 is measured across the cracks in the intermetallic film at room temperature. Cracks are easily formed with low-frequency voltage cycling and remain stable when the device is operated at high frequency, which offers intriguing potential for next-generation high-frequency memory applications. Moreover, endurance testing demonstrates that the opening and closing of such cracks canmore » reach over 10 7 cycles under 10-μs pulses, without catastrophic failure of the film.« less

  15. Electrically reversible cracks in an intermetallic film controlled by an electric field

    DOE PAGES

    Liu, Z. Q.; Liu, J. H.; Biegalski, M. D.; ...

    2018-01-03

    Cracks in solid-state materials are typically irreversible. We report electrically reversible opening and closing of nanoscale cracks in an intermetallic thin film grown on a ferroelectric substrate driven by a small electric field (~0.83 kV/cm). Accordingly, a nonvolatile colossal electroresistance on-off ratio of more than 10 8 is measured across the cracks in the intermetallic film at room temperature. Cracks are easily formed with low-frequency voltage cycling and remain stable when the device is operated at high frequency, which offers intriguing potential for next-generation high-frequency memory applications. Moreover, endurance testing demonstrates that the opening and closing of such cracks canmore » reach over 10 7 cycles under 10-μs pulses, without catastrophic failure of the film.« less

  16. Efficient Blood-Brain Barrier Opening in Primates with Neuronavigation-Guided Ultrasound and Real-Time Acoustic Mapping.

    PubMed

    Wu, Shih-Ying; Aurup, Christian; Sanchez, Carlos Sierra; Grondin, Julien; Zheng, Wenlan; Kamimura, Hermes; Ferrera, Vincent P; Konofagou, Elisa E

    2018-05-22

    Brain diseases including neurological disorders and tumors remain under treated due to the challenge to access the brain, and blood-brain barrier (BBB) restricting drug delivery which, also profoundly limits the development of pharmacological treatment. Focused ultrasound (FUS) with microbubbles is the sole method to open the BBB noninvasively, locally, and transiently and facilitate drug delivery, while translation to the clinic is challenging due to long procedure, targeting limitations, or invasiveness of current systems. In order to provide rapid, flexible yet precise applications, we have designed a noninvasive FUS and monitoring system with the protocol tested in monkeys (from in silico preplanning and simulation, real-time targeting and acoustic mapping, to post-treatment assessment). With a short procedure (30 min) similar to current clinical imaging duration or radiation therapy, the achieved targeting (both cerebral cortex and subcortical structures) and monitoring accuracy was close to the predicted 2-mm lower limit. This system would enable rapid clinical transcranial FUS applications outside of the MRI system without a stereotactic frame, thereby benefiting patients especially in the elderly population.

  17. Ensemble: an Architecture for Mission-Operations Software

    NASA Technical Reports Server (NTRS)

    Norris, Jeffrey; Powell, Mark; Fox, Jason; Rabe, Kenneth; Shu, IHsiang; McCurdy, Michael; Vera, Alonso

    2008-01-01

    Ensemble is the name of an open architecture for, and a methodology for the development of, spacecraft mission operations software. Ensemble is also potentially applicable to the development of non-spacecraft mission-operations- type software. Ensemble capitalizes on the strengths of the open-source Eclipse software and its architecture to address several issues that have arisen repeatedly in the development of mission-operations software: Heretofore, mission-operations application programs have been developed in disparate programming environments and integrated during the final stages of development of missions. The programs have been poorly integrated, and it has been costly to develop, test, and deploy them. Users of each program have been forced to interact with several different graphical user interfaces (GUIs). Also, the strategy typically used in integrating the programs has yielded serial chains of operational software tools of such a nature that during use of a given tool, it has not been possible to gain access to the capabilities afforded by other tools. In contrast, the Ensemble approach offers a low-risk path towards tighter integration of mission-operations software tools.

  18. Harvest: an open platform for developing web-based biomedical data discovery and reporting applications.

    PubMed

    Pennington, Jeffrey W; Ruth, Byron; Italia, Michael J; Miller, Jeffrey; Wrazien, Stacey; Loutrel, Jennifer G; Crenshaw, E Bryan; White, Peter S

    2014-01-01

    Biomedical researchers share a common challenge of making complex data understandable and accessible as they seek inherent relationships between attributes in disparate data types. Data discovery in this context is limited by a lack of query systems that efficiently show relationships between individual variables, but without the need to navigate underlying data models. We have addressed this need by developing Harvest, an open-source framework of modular components, and using it for the rapid development and deployment of custom data discovery software applications. Harvest incorporates visualizations of highly dimensional data in a web-based interface that promotes rapid exploration and export of any type of biomedical information, without exposing researchers to underlying data models. We evaluated Harvest with two cases: clinical data from pediatric cardiology and demonstration data from the OpenMRS project. Harvest's architecture and public open-source code offer a set of rapid application development tools to build data discovery applications for domain-specific biomedical data repositories. All resources, including the OpenMRS demonstration, can be found at http://harvest.research.chop.edu.

  19. Harvest: an open platform for developing web-based biomedical data discovery and reporting applications

    PubMed Central

    Pennington, Jeffrey W; Ruth, Byron; Italia, Michael J; Miller, Jeffrey; Wrazien, Stacey; Loutrel, Jennifer G; Crenshaw, E Bryan; White, Peter S

    2014-01-01

    Biomedical researchers share a common challenge of making complex data understandable and accessible as they seek inherent relationships between attributes in disparate data types. Data discovery in this context is limited by a lack of query systems that efficiently show relationships between individual variables, but without the need to navigate underlying data models. We have addressed this need by developing Harvest, an open-source framework of modular components, and using it for the rapid development and deployment of custom data discovery software applications. Harvest incorporates visualizations of highly dimensional data in a web-based interface that promotes rapid exploration and export of any type of biomedical information, without exposing researchers to underlying data models. We evaluated Harvest with two cases: clinical data from pediatric cardiology and demonstration data from the OpenMRS project. Harvest's architecture and public open-source code offer a set of rapid application development tools to build data discovery applications for domain-specific biomedical data repositories. All resources, including the OpenMRS demonstration, can be found at http://harvest.research.chop.edu PMID:24131510

  20. The present situation of the irradiation application industry and irradiation facilities in Japan

    NASA Astrophysics Data System (ADS)

    Mizusawa, K.; Baba, T.

    2003-08-01

    The irradiation application industry and irradiation facilities in Japan have been making slow but steady progress for the past 2-3 years. Beside conventional applications, new ones such as carbon fibers and membrane filters have come into the market. There are a lot of new applications about to emerge. PE tubing, already is in the European market, is being evaluated by end users in Japan. Cleaning of dioxin in exhaust gas was successfully tested at a pilot plant. Cross-linked PTFE and polyamide are waiting customers' evaluations as an engineering plastic. Surface cross-linking of artificial polycarbonate teeth has yielded remarkable experimental results. Cross-linking of polycaprolactone will be useful for biodegradable products. Being aware of the future growth of irradiation industry, contract service providers opened new facilities or increased their capability. Beside in-house facilities, there are now three Co-60 facilities and nine EB facilities available for contract irradiation in Japan.

  1. Influences of deep learning, need for cognition and preparation time on open- and closed-book test performance.

    PubMed

    Heijne-Penninga, Marjolein; Kuks, Jan B M; Hofman, W H Adriaan; Cohen-Schotanus, Janke

    2010-09-01

    The ability to master discipline-specific knowledge is one of the competencies medical students must acquire. In this context, 'mastering' means being able to recall and apply knowledge. A way to assess this competency is to use both open- and closed-book tests. Student performance on both tests can be influenced by the way the student processes information. Deep information processing is expected to influence performance positively. The personal preferences of students in relation to how they process information in general (i.e. their level of need for cognition) may also be of importance. In this study, we examined the inter-relatedness of deep learning, need for cognition and preparation time, and scores on open- and closed-book tests. This study was conducted at the University Medical Centre Groningen. Participants were Year 2 students (n = 423). They were asked to complete a questionnaire on deep information processing, a scale for need for cognition on a questionnaire on intellectualism and, additionally, to write down the time they spent on test preparation. We related these measures to the students' scores on two tests, both consisting of open- and closed-book components and used structural equation modelling to analyse the data. Both questionnaires were completed by 239 students (57%). The results showed that need for cognition positively influenced both open- and closed-book test scores (beta-coefficients 0.05 and 0.11, respectively). Furthermore, study outcomes measured by open-book tests predicted closed-book test results better than the other way around (beta-coefficients 0.72 and 0.11, respectively). Students with a high need for cognition performed better on open- as well as closed-book tests. Deep learning did not influence their performance. Adding open-book tests to the regularly used closed-book tests seems to improve the recall of knowledge that has to be known by heart. Need for cognition may provide a valuable addition to existing theories on learning.

  2. D Data Acquisition Based on Opencv for Close-Range Photogrammetry Applications

    NASA Astrophysics Data System (ADS)

    Jurjević, L.; Gašparović, M.

    2017-05-01

    Development of the technology in the area of the cameras, computers and algorithms for 3D the reconstruction of the objects from the images resulted in the increased popularity of the photogrammetry. Algorithms for the 3D model reconstruction are so advanced that almost anyone can make a 3D model of photographed object. The main goal of this paper is to examine the possibility of obtaining 3D data for the purposes of the close-range photogrammetry applications, based on the open source technologies. All steps of obtaining 3D point cloud are covered in this paper. Special attention is given to the camera calibration, for which two-step process of calibration is used. Both, presented algorithm and accuracy of the point cloud are tested by calculating the spatial difference between referent and produced point clouds. During algorithm testing, robustness and swiftness of obtaining 3D data is noted, and certainly usage of this and similar algorithms has a lot of potential in the real-time application. That is the reason why this research can find its application in the architecture, spatial planning, protection of cultural heritage, forensic, mechanical engineering, traffic management, medicine and other sciences.

  3. Health figures: an open source JavaScript library for health data visualization.

    PubMed

    Ledesma, Andres; Al-Musawi, Mohammed; Nieminen, Hannu

    2016-03-22

    The way we look at data has a great impact on how we can understand it, particularly when the data is related to health and wellness. Due to the increased use of self-tracking devices and the ongoing shift towards preventive medicine, better understanding of our health data is an important part of improving the general welfare of the citizens. Electronic Health Records, self-tracking devices and mobile applications provide a rich variety of data but it often becomes difficult to understand. We implemented the hFigures library inspired on the hGraph visualization with additional improvements. The purpose of the library is to provide a visual representation of the evolution of health measurements in a complete and useful manner. We researched the usefulness and usability of the library by building an application for health data visualization in a health coaching program. We performed a user evaluation with Heuristic Evaluation, Controlled User Testing and Usability Questionnaires. In the Heuristics Evaluation the average response was 6.3 out of 7 points and the Cognitive Walkthrough done by usability experts indicated no design or mismatch errors. In the CSUQ usability test the system obtained an average score of 6.13 out of 7, and in the ASQ usability test the overall satisfaction score was 6.64 out of 7. We developed hFigures, an open source library for visualizing a complete, accurate and normalized graphical representation of health data. The idea is based on the concept of the hGraph but it provides additional key features, including a comparison of multiple health measurements over time. We conducted a usability evaluation of the library as a key component of an application for health and wellness monitoring. The results indicate that the data visualization library was helpful in assisting users in understanding health data and its evolution over time.

  4. Employing Nested OpenMP for the Parallelization of Multi-Zone Computational Fluid Dynamics Applications

    NASA Technical Reports Server (NTRS)

    Ayguade, Eduard; Gonzalez, Marc; Martorell, Xavier; Jost, Gabriele

    2004-01-01

    In this paper we describe the parallelization of the multi-zone code versions of the NAS Parallel Benchmarks employing multi-level OpenMP parallelism. For our study we use the NanosCompiler, which supports nesting of OpenMP directives and provides clauses to control the grouping of threads, load balancing, and synchronization. We report the benchmark results, compare the timings with those of different hybrid parallelization paradigms and discuss OpenMP implementation issues which effect the performance of multi-level parallel applications.

  5. Alaska Department of Labor and Workforce Development

    Science.gov Websites

    Applications and Permits Employment Application (PDF) (Word) Youth Work Permit (PDF) Post a Job To advertise a job opening to Alaska job seekers, post a job on Alexsys. ALEXsys Alaska's Job Bank The job opening

  6. Development of the anode bipolar plate/membrane assembly unit for air breathing PEMFC stack using silicone adhesive bonding

    NASA Astrophysics Data System (ADS)

    Kim, Minkook; Lee, Dai Gil

    2016-05-01

    Polymer electrolyte membrane fuel cells (PEMFC) exhibit a wide power range, low operating temperature, high energy density and long life time. These advantages favor PEMFC for applications such as vehicle power sources, portable power, and backup power applications. With the push towards the commercialization of PEMFC, especially for portable power applications, the overall balance of plants (BOPs) of the systems should be minimized. To reduce the mass and complexity of the systems, air-breathing PEMFC stack design with open cathode channel configuration is being developed. However, the open cathode channel configuration incurs hydrogen leakage problem. In this study, the bonding strength of a silicon adhesive between the Nafion membrane and the carbon fiber/epoxy composite bipolar plate was measured. Then, an anode bipolar plate/membrane assembly unit which was bonded with the silicone adhesive was developed to solve the hydrogen leakage problem. The reliability of the anode bipolar plate/membrane assembly unit was estimated under the internal pressure of hydrogen by the FE analysis. Additionally, the gas sealability of the developed air breathing PEMFC unit cell was experimentally measured. Finally, unit cell performance of the developed anode bipolar plate/membrane assembly unit was tested and verified under operating conditions without humidity and temperature control.

  7. Conformance testing strategies for DICOM protocols in a heterogenous communications system

    NASA Astrophysics Data System (ADS)

    Meyer, Ralph; Hewett, Andrew J.; Cordonnier, Emmanuel; Piqueras, Joachim; Jensch, Peter F.

    1995-05-01

    The goal of the DICOM standard is to define a standard network interface and data model for imaging devices from various vendors. It shall facilitate the development and integration of information systems and picture archiving and communication systems (PACS) in a networked environment. Current activities in Oldenburg, Germany include projects to establish cooperative work applications for radiological purposes, comprising (joined) text, data, signal and image communications, based on narrowband ISDN and ATM communication for regional and Pan European applications. In such a growing and constantly changing environment it is vital to have a solid and implementable plan to bring standards in operation. A communication standard alone cannot ensure interoperability between different vendor implementations. Even DICOM does not specify implementation-specific requirements nor does it specify a testing procedure to assess an implementation's conformance to the standard. The conformance statements defined in the DICOM standard only allow a user to determine which optional components are supported by the implementation. The goal of our work is to build a conformance test suite for DICOM. Conformance testing can aid to simplify and solve problems with multivendor systems. It will check a vendor's implementation against the DICOM standard and state the found subset of functionality. The test suite will be built in respect to the ISO 9646 Standard (OSI-Conformance Testing Methodology and Framework) which is a standard devoted to the subject of conformance testing implementations of Open Systems Interconnection (OSI) standards. For our heterogeneous communication environments we must also consider ISO 9000 - 9004 (quality management and quality assurance) to give the users the confidence in evolving applications.

  8. Influence of PBL with open-book tests on knowledge retention measured with progress tests.

    PubMed

    Heijne-Penninga, M; Kuks, J B M; Hofman, W H A; Muijtjens, A M M; Cohen-Schotanus, J

    2013-08-01

    The influence of problem-based learning (PBL) and open-book tests on long-term knowledge retention is unclear and subject of discussion. Hypotheses were that PBL as well as open-book tests positively affect long-term knowledge retention. Four progress test results of fifth and sixth-year medical students (n = 1,648) of three medical schools were analyzed. Two schools had PBL driven curricula, and the third one had a traditional curriculum (TC). One of the PBL schools (PBLob) used a combination of open-book (assessing backup knowledge) and closed-book tests (assessing core knowledge); the other two schools (TC and PBLcb) only used closed-book tests. The items of the progress tests were divided into core and backup knowledge. T tests (with Bonferroni correction) were used to analyze differences between curricula. PBL students performed significantly better than TC students on core knowledge (average effect size (av ES) = 0.37-0.74) and PBL students tested with open-book tests scored somewhat higher than PBL students tested without such tests (av ES = 0.23-0.30). Concerning backup knowledge, no differences were found between the scores of the three curricula. Students of the two PBL curricula showed a substantially better long-term knowledge retention than TC students. PBLob students performed somewhat better on core knowledge than PBLcb students. These outcomes suggest that a problem-based instructional approach in particular can stimulate long-term knowledge retention. Distinguishing knowledge into core and backup knowledge and using open-book tests alongside closed-book tests could enhance long-term core knowledge retention.

  9. MHD generator electrode development. Summary report, July 1, 1981-September 30, 1982

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rossing, B.R.; Buckman, R.W. Jr.; Pouchot, W.D.

    Emphasis on this program was the development of and understanding wastage mechanism(s) of metallic electrodes which may be suitable alternatives to platinum anode material for use in long-term open cycle, coal-fired MHD generator operations. The laboratory tests simulate both modes of material wastage observed in MHD electrode operation; i.e., arc erosion (melting/vaporization) and electrochemical corrosion. Based on experimental results from the electrochemical tests at 1473/sup 0/K, the rank order listing of the materials tested for anode applications were platinum, E-Brite 26-1 modified with a five percent addition of platinum, chromium, IN 601, E-Brite 26-1, and 330 stainless steel ranked inmore » decreasing order. The rank order listing based on the arc erosion test was platinum, chromium, E-Brite 26-1, 330 stainless steel, and IN 601. The relative arc erosion resistance of materials based on the AVCO Mark VII generator test results gave a rank order of platinum, 330 stainless steel, IN 601, and E-Brite 26-1. Engineering tests under simulated open-cycle coal-fired MHD operating conditions were performed in the 500 kW Westinghouse Electrode System Test Facility (WESTF). Tests were conducted on candidate metallic anode materials (cold wall) and ceramic anode (hot wall) materials. A ten-hour duration cold wall slagging test was conducted on platinum, E-Brite 26-1, 330 stainless steel and IN 601 and the results were similar to those obtained for those materials in the AVCO Mark VII generator tests. Non-slagging, super hot (>1700/sup 0/C) wall hafnia-rare earth oxide electrodes were tested in a sulfurous, western coal-fired MHD environment. All four ceramic electrode pairs were destroyed. 20 references.« less

  10. Behaviour and design considerations for continuous flow closed-open-closed liquid microchannels.

    PubMed

    Melin, Jessica; van der Wijngaart, Wouter; Stemme, Göran

    2005-06-01

    This paper introduces a method of combining open and closed microchannels in a single component in a novel way which couples the benefits of both open and closed microfluidic systems and introduces interesting on-chip microfluidic behaviour. Fluid behaviour in such a component, based on continuous pressure driven flow and surface tension, is discussed in terms of cross sectional flow behaviour, robustness, flow-pressure performance, and its application to microfluidic interfacing. The closed-open-closed microchannel possesses the versatility of upstream and downstream closed microfluidics along with open fluidic direct access. The device has the advantage of eliminating gas bubbles present upstream when these enter the open channel section. The unique behaviour of this device opens the door to applications including direct liquid sample interfacing without the need for additional and bulky sample tubing.

  11. Solenoid hammer valve developed for quick-opening requirements

    NASA Technical Reports Server (NTRS)

    Wrench, E. H.

    1967-01-01

    Quick-opening lightweight solenoid hammer valve requires a low amount of electrical energy to open, and closes by the restoring action of the mechanical springs. This design should be applicable to many quick-opening requirements in fluid systems.

  12. Benchmarking natural-language parsers for biological applications using dependency graphs.

    PubMed

    Clegg, Andrew B; Shepherd, Adrian J

    2007-01-25

    Interest is growing in the application of syntactic parsers to natural language processing problems in biology, but assessing their performance is difficult because differences in linguistic convention can falsely appear to be errors. We present a method for evaluating their accuracy using an intermediate representation based on dependency graphs, in which the semantic relationships important in most information extraction tasks are closer to the surface. We also demonstrate how this method can be easily tailored to various application-driven criteria. Using the GENIA corpus as a gold standard, we tested four open-source parsers which have been used in bioinformatics projects. We first present overall performance measures, and test the two leading tools, the Charniak-Lease and Bikel parsers, on subtasks tailored to reflect the requirements of a system for extracting gene expression relationships. These two tools clearly outperform the other parsers in the evaluation, and achieve accuracy levels comparable to or exceeding native dependency parsers on similar tasks in previous biological evaluations. Evaluating using dependency graphs allows parsers to be tested easily on criteria chosen according to the semantics of particular biological applications, drawing attention to important mistakes and soaking up many insignificant differences that would otherwise be reported as errors. Generating high-accuracy dependency graphs from the output of phrase-structure parsers also provides access to the more detailed syntax trees that are used in several natural-language processing techniques.

  13. Benchmarking natural-language parsers for biological applications using dependency graphs

    PubMed Central

    Clegg, Andrew B; Shepherd, Adrian J

    2007-01-01

    Background Interest is growing in the application of syntactic parsers to natural language processing problems in biology, but assessing their performance is difficult because differences in linguistic convention can falsely appear to be errors. We present a method for evaluating their accuracy using an intermediate representation based on dependency graphs, in which the semantic relationships important in most information extraction tasks are closer to the surface. We also demonstrate how this method can be easily tailored to various application-driven criteria. Results Using the GENIA corpus as a gold standard, we tested four open-source parsers which have been used in bioinformatics projects. We first present overall performance measures, and test the two leading tools, the Charniak-Lease and Bikel parsers, on subtasks tailored to reflect the requirements of a system for extracting gene expression relationships. These two tools clearly outperform the other parsers in the evaluation, and achieve accuracy levels comparable to or exceeding native dependency parsers on similar tasks in previous biological evaluations. Conclusion Evaluating using dependency graphs allows parsers to be tested easily on criteria chosen according to the semantics of particular biological applications, drawing attention to important mistakes and soaking up many insignificant differences that would otherwise be reported as errors. Generating high-accuracy dependency graphs from the output of phrase-structure parsers also provides access to the more detailed syntax trees that are used in several natural-language processing techniques. PMID:17254351

  14. Rapamycin blocks the antidepressant effect of ketamine in task-dependent manner.

    PubMed

    Holubova, Kristina; Kleteckova, Lenka; Skurlova, Martina; Ricny, Jan; Stuchlik, Ales; Vales, Karel

    2016-06-01

    The aim of our study was to test whether ketamine produces an antidepressant effect in animal model of olfactory bulbectomy and assess the role of mammalian target of rapamycin (mTOR) pathway in ketamine's antidepressant effect. Bulbectomized (OBX) rats and sham controls were assigned to four subgroups according to the treatment they received (ketamine, saline, ketamine + rapamycin, and saline + rapamycin). The animals were subjected to open field (OF), elevated plus maze (EPM), passive avoidance (PA), Morris water maze (MWM), and Carousel maze (CM) tests. Blood samples were collected before and after drug administration for analysis of phosphorylated mTOR level. After behavioral testing, brains were removed for evaluation of brain-derived neurotrophic factor (BDNF) in prefrontal cortex (PFC) and hippocampus. Ketamine normalized hyperactivity of OBX animals in EPM and increased the time spent in open arms. Rapamycin pretreatment resulted in elimination of ketamine effect in EPM test. In CM test, ketamine + rapamycin administration led to cognitive impairment not observed in saline-, ketamine-, or saline + rapamycin-treated OBX rats. Prefrontal BDNF content was significantly decreased, and level of mTOR was significantly elevated in OBX groups. OBX animals significantly differed from sham controls in most of the tests used. Treatment had more profound effect on OBX phenotype than controls. Pretreatment with rapamycin eliminated the anxiolytic and antidepressant effects of ketamine in task-dependent manner. The results indicate that ketamine + rapamycin application resulted in impaired stress responses manifested by cognitive deficits in active place avoidance (CM) test. Intensity of stressor (mild vs. severe) used in the behavioral tests had opposite effect on controls and on OBX animals.

  15. Plowshare Program - American Atomic Bomb Tests For Industrial Applications

    ScienceCinema

    None

    2018-01-16

    The United States Atomic Energy Commission (AEC) established the Plowshare Program as a research and development activity to explore the technical and economic feasibility of using nuclear explosives for industrial applications. The reasoning was that the relatively inexpensive energy available from nuclear explosions could prove useful for a wide variety of peaceful purposes. The Plowshare Program began in 1958 and continued through 1975. Between December 1961 and May 1973, the United States conducted 27 Plowshare nuclear explosive tests comprising 35 individual detonations. Conceptually, industrial applications resulting from the use of nuclear explosives could be divided into two broad categories: 1) large-scale excavation and quarrying, where the energy from the explosion was used to break up and/or move rock; and 2) underground engineering, where the energy released from deeply buried nuclear explosives increased the permeability and porosity of the rock by massive breaking and fracturing. Possible excavation applications included: canals, harbors, highway and railroad cuts through mountains, open pit mining, construction of dams, and other quarry and construction-related projects. Underground nuclear explosion applications included: stimulation of natural gas production, preparation of leachable ore bodies for in situ leaching, creation of underground zones of fractured oil shale for in situ retorting, and formation of underground natural gas and petroleum storage reservoirs.

  16. Plowshare Program - American Atomic Bomb Tests For Industrial Applications

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    None

    2012-04-22

    The United States Atomic Energy Commission (AEC) established the Plowshare Program as a research and development activity to explore the technical and economic feasibility of using nuclear explosives for industrial applications. The reasoning was that the relatively inexpensive energy available from nuclear explosions could prove useful for a wide variety of peaceful purposes. The Plowshare Program began in 1958 and continued through 1975. Between December 1961 and May 1973, the United States conducted 27 Plowshare nuclear explosive tests comprising 35 individual detonations. Conceptually, industrial applications resulting from the use of nuclear explosives could be divided into two broad categories: 1)more » large-scale excavation and quarrying, where the energy from the explosion was used to break up and/or move rock; and 2) underground engineering, where the energy released from deeply buried nuclear explosives increased the permeability and porosity of the rock by massive breaking and fracturing. Possible excavation applications included: canals, harbors, highway and railroad cuts through mountains, open pit mining, construction of dams, and other quarry and construction-related projects. Underground nuclear explosion applications included: stimulation of natural gas production, preparation of leachable ore bodies for in situ leaching, creation of underground zones of fractured oil shale for in situ retorting, and formation of underground natural gas and petroleum storage reservoirs.« less

  17. Reestablishing Open Rotor as an Option for Significant Fuel Burn Improvements

    NASA Technical Reports Server (NTRS)

    Van Zante, Dale

    2011-01-01

    A low-noise open rotor system is being tested in collaboration with General Electric and CFM International, a 50/50 joint company between Snecma and GE. Candidate technologies for lower noise will be investigated as well as installation effects such as pylon integration. Current test status is presented as well as future scheduled testing which includes the FAA/CLEEN test entry. Pre-test predictions show that Open Rotors have the potential for revolutionary fuel burn savings.

  18. 18 CFR 157.33 - Requirement for open season.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 18 Conservation of Power and Water Resources 1 2011-04-01 2011-04-01 false Requirement for open... GAS ACT Open Seasons for Alaska Natural Gas Transportation Projects § 157.33 Requirement for open... applicant has conducted an open season for capacity on its proposed project, in accordance with the...

  19. 18 CFR 157.34 - Notice of open season.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Notice of open season... ACT Open Seasons for Alaska Natural Gas Transportation Projects § 157.34 Notice of open season. (a) Notice. A prospective applicant must provide reasonable public notice of an open season through methods...

  20. 18 CFR 157.34 - Notice of open season.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Notice of open season... ACT Open Seasons for Alaska Natural Gas Transportation Projects § 157.34 Notice of open season. (a) Notice. A prospective applicant must provide reasonable public notice of an open season through methods...

  1. 18 CFR 157.33 - Requirement for open season.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Requirement for open... GAS ACT Open Seasons for Alaska Natural Gas Transportation Projects § 157.33 Requirement for open... applicant has conducted an open season for capacity on its proposed project, in accordance with the...

  2. 18 CFR 157.33 - Requirement for open season.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 18 Conservation of Power and Water Resources 1 2014-04-01 2014-04-01 false Requirement for open... GAS ACT Open Seasons for Alaska Natural Gas Transportation Projects § 157.33 Requirement for open... applicant has conducted an open season for capacity on its proposed project, in accordance with the...

  3. 18 CFR 157.33 - Requirement for open season.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 18 Conservation of Power and Water Resources 1 2012-04-01 2012-04-01 false Requirement for open... GAS ACT Open Seasons for Alaska Natural Gas Transportation Projects § 157.33 Requirement for open... applicant has conducted an open season for capacity on its proposed project, in accordance with the...

  4. 18 CFR 157.34 - Notice of open season.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 18 Conservation of Power and Water Resources 1 2013-04-01 2013-04-01 false Notice of open season... ACT Open Seasons for Alaska Natural Gas Transportation Projects § 157.34 Notice of open season. (a) Notice. A prospective applicant must provide reasonable public notice of an open season through methods...

  5. 18 CFR 157.33 - Requirement for open season.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Requirement for open... GAS ACT Open Seasons for Alaska Natural Gas Transportation Projects § 157.33 Requirement for open... applicant has conducted an open season for capacity on its proposed project, in accordance with the...

  6. Combining skin prick, immediate skin application and specific-IgE testing in the diagnosis of peanut allergy in children.

    PubMed

    Wainstein, Brynn Kevin; Yee, Anthony; Jelley, Donna; Ziegler, Mary; Ziegler, John B

    2007-05-01

    Previous studies have suggested various diagnostic cut-offs of allergy tests for the diagnosis of clinical peanut allergy in children. There are few data relating to the use of combinations of these tests in children. We aimed to determine the validity of previously reported diagnostic cut-off levels of peanut allergen skin tests and peanut specific-immunoglobulin (Ig) E, as well as the usefulness of combinations of these, for predicting clinical peanut allergy in our Allergy Clinic. Children attending the Allergy Clinic with a positive peanut skin prick test (SPT; n = 84) were included in the study. Immediate skin application food tests (I-SAFT) using 1 g of peanut butter (positive if any wheals were detected at 15 min), peanut specific-IgE levels and open-label peanut food challenges were performed. Fifty-two of 85 peanut challenges were positive. Skin prick test specificity was 67% at >or=8 mm and 100% at >or=15 mm. The I-SAFT was 82% specific. A peanut specific-IgE level of 0.37 kU/l was 98% sensitive but 33% specific. A level of 10 kU/l was 100% specific. Combinations of a SPT of >or=8 mm with a positive I-SAFT and a peanut specific-IgE >or=0.37 kU/l were 88% specific with a sensitivity of 38%. Using challenge outcomes as the standard, available in vitro and in vivo diagnostic tests for peanut allergy have poor sensitivity and specificity and combining them does not significantly improve their clinical usefulness. Previously described diagnostic cut-off levels do not have general applicability. Allergy practitioners may need to interpret results of allergy tests in the context of their own practices.

  7. Colloquium: Non-Markovian dynamics in open quantum systems

    NASA Astrophysics Data System (ADS)

    Breuer, Heinz-Peter; Laine, Elsi-Mari; Piilo, Jyrki; Vacchini, Bassano

    2016-04-01

    The dynamical behavior of open quantum systems plays a key role in many applications of quantum mechanics, examples ranging from fundamental problems, such as the environment-induced decay of quantum coherence and relaxation in many-body systems, to applications in condensed matter theory, quantum transport, quantum chemistry, and quantum information. In close analogy to a classical Markovian stochastic process, the interaction of an open quantum system with a noisy environment is often modeled phenomenologically by means of a dynamical semigroup with a corresponding time-independent generator in Lindblad form, which describes a memoryless dynamics of the open system typically leading to an irreversible loss of characteristic quantum features. However, in many applications open systems exhibit pronounced memory effects and a revival of genuine quantum properties such as quantum coherence, correlations, and entanglement. Here recent theoretical results on the rich non-Markovian quantum dynamics of open systems are discussed, paying particular attention to the rigorous mathematical definition, to the physical interpretation and classification, as well as to the quantification of quantum memory effects. The general theory is illustrated by a series of physical examples. The analysis reveals that memory effects of the open system dynamics reflect characteristic features of the environment which opens a new perspective for applications, namely, to exploit a small open system as a quantum probe signifying nontrivial features of the environment it is interacting with. This Colloquium further explores the various physical sources of non-Markovian quantum dynamics, such as structured environmental spectral densities, nonlocal correlations between environmental degrees of freedom, and correlations in the initial system-environment state, in addition to developing schemes for their local detection. Recent experiments addressing the detection, quantification, and control of non-Markovian quantum dynamics are also briefly discussed.

  8. Early application of tail nerve electrical stimulation-induced walking training promotes locomotor recovery in rats with spinal cord injury.

    PubMed

    Zhang, S-X; Huang, F; Gates, M; Shen, X; Holmberg, E G

    2016-11-01

    This is a randomized controlled prospective trial with two parallel groups. The objective of this study was to determine whether early application of tail nerve electrical stimulation (TANES)-induced walking training can improve the locomotor function. This study was conducted in SCS Research Center in Colorado, USA. A contusion injury to spinal cord T10 was produced using the New York University impactor device with a 25 -mm height setting in female, adult Long-Evans rats. Injured rats were randomly divided into two groups (n=12 per group). One group was subjected to TANES-induced walking training 2 weeks post injury, and the other group, as control, received no TANES-induced walking training. Restorations of behavior and conduction were assessed using the Basso, Beattie and Bresnahan open-field rating scale, horizontal ladder rung walking test and electrophysiological test (Hoffmann reflex). Early application of TANES-induced walking training significantly improved the recovery of locomotor function and benefited the restoration of Hoffmann reflex. TANES-induced walking training is a useful method to promote locomotor recovery in rats with spinal cord injury.

  9. Policy analysis and recommendations for the open source application development portal (OSADP).

    DOT National Transportation Integrated Search

    2012-06-01

    This white paper addresses the policy and institutional issues that are associated with the development of an open source applications development portal (OSADP), part of a larger research effort being conducted under the ITS Programs Dynamic Mobi...

  10. Recent Accomplishments in Laser-Photovoltaic Wireless Power Transmission

    NASA Technical Reports Server (NTRS)

    Fikes, John C.; Henley, Mark W.; Mankins, John C.; Howell, Joe T.; Fork, Richard L.; Cole, Spencer T.; Skinner, Mark

    2003-01-01

    Wireless power transmission can be accomplished over long distances using laser power sources and photovoltaic receivers. Recent research at AMOS has improved our understanding of the use of this technology for practical applications. Research by NASA, Boeing, the University of Alabama-Huntsville, the University of Colorado, Harvey Mudd College, and the Naval Postgraduate School has tested various commercial lasers and photovoltaic receiver configurations. Lasers used in testing have included gaseous argon and krypton, solid-state diodes, and fiber optic sources, at wavelengths ranging from the visible to the near infra-red. A variety of Silicon and Gallium Arsenide photovoltaic have been tested with these sources. Safe operating procedures have been established, and initial tests have been conducted in the open air at AMOS facilities. This research is progressing toward longer distance ground demonstrations of the technology and practical near-term space demonstrations.

  11. Interstellar reddening information system

    NASA Astrophysics Data System (ADS)

    Burnashev, V. I.; Grigorieva, E. A.; Malkov, O. Yu.

    2013-10-01

    We describe an electronic bibliographic information system, based on a card catalog, containing some 2500 references (publications of 1930-2009) on interstellar extinction. We have classified the articles according to their content. We present here a list of articles devoted to two categories: maps of total extinction and variation of interstellar extinction with the distance to the object. The catalog is tested using published data on open clusters, and conclusions on the applicability of different maps of interstellar extinctions for various distances are made.

  12. Agenda: EDRN FDA Education Workshop — EDRN Public Portal

    Cancer.gov

    The purpose of this workshop was to open dialogue between FDA staff that provide oversight for review of in vitro diagnostic applications and EDRN scientists currently performing clinical validation studies on cancer biomarkers. Issues related to FDA review of diagnostic tests were presented by FDA personnel. Representatives from EDRN provided details on supporting data of their validation studies and the resources developed within EDRN to facilitate such research for FDA compliance. The agenda provided here provides links to the presentations by each speaker.

  13. Reconfigurable Software for Mission Operations

    NASA Technical Reports Server (NTRS)

    Trimble, Jay

    2014-01-01

    We developed software that provides flexibility to mission organizations through modularity and composability. Modularity enables removal and addition of functionality through the installation of plug-ins. Composability enables users to assemble software from pre-built reusable objects, thus reducing or eliminating the walls associated with traditional application architectures and enabling unique combinations of functionality. We have used composable objects to reduce display build time, create workflows, and build scenarios to test concepts for lunar roving operations. The software is open source, and may be downloaded from https:github.comnasamct.

  14. Analysis and application of a velocity command motor as a reaction mass actuator

    NASA Technical Reports Server (NTRS)

    Sulla, Jeffrey L.; Juang, Jer-Nan; Horta, Lucas G.

    1990-01-01

    A commercially available linear stepper motor is applied as a reaction mass (RM) actuator. With the actuator operating in the (RM) relative-velocity command mode, open-loop and closed-loop testing is performed to determine operational limits. With the actuator mounted on a simple beam structure, root strain, RM acceleration, or beam acceleration is used in the feedback loop to augment the structural damping. The RM relative position is also used as feedback to ensure that the RM remains centered.

  15. Deploying the ATLAS Metadata Interface (AMI) on the cloud with Jenkins

    NASA Astrophysics Data System (ADS)

    Lambert, F.; Odier, J.; Fulachier, J.; ATLAS Collaboration

    2017-10-01

    The ATLAS Metadata Interface (AMI) is a mature application of more than 15 years of existence. Mainly used by the ATLAS experiment at CERN, it consists of a very generic tool ecosystem for metadata aggregation and cataloguing. AMI is used by the ATLAS production system, therefore the service must guarantee a high level of availability. We describe our monitoring and administration systems, and the Jenkins-based strategy used to dynamically test and deploy cloud OpenStack nodes on demand.

  16. 76 FR 74721 - Preserving the Open Internet

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-12-01

    ...; Report No. 2936] Preserving the Open Internet AGENCY: Federal Communications Commission. ACTION: Final... for broadband service to preserve and reinforce Internet freedom and openness. DATES: Oppositions to... applicability. Subject: In the Matter of Preserving the Open Internet, Broadband Industry Practices, published...

  17. Integrated Application of Active Controls (IAAC) technology to an advanced subsonic transport project: Program review

    NASA Technical Reports Server (NTRS)

    1986-01-01

    This report summarizes the Integrated Application of Active Controls (IAAC) Technology to an Advanced Subsonic Transport Project, established as one element of the NASA/Boeing Energy Efficient Transport Technology Program. The performance assessment showed that incorporating ACT into an airplane designed to fly approximately 200 passengers approximately 2,000 nmi could yield block fuel savings from 6 to 10 percent at the design range. The principal risks associated with incorporating these active control functions into a commercial airplane are those involved with the ACT system implementation. The Test and Evaluation phase of the IAAC Project focused on the design, fabrication, and test of a system that implemented pitch axis fly-by-wire, pitch axis augmentation, and wing load alleviation. The system was built to be flight worthy, and was planned to be experimentally flown on the 757. The system was installed in the Boeing Digital Avionics Flight Controls Laboratory (DAFCL), where open loop hardware and software tests, and a brief examination of a direct drive valve (DDV) actuation concept were accomplished. The IAAC Project has shown that ACT can be beneficially incorporated into a commercial transport airplane. Based on the results achieved during the testing phase, there appears to be no fundamental reason(s) that would preclude the commercial application of ACT, assuming an appropriate development effort is included.

  18. 42 CFR 84.95 - Service time test; open-circuit apparatus.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... classified according to the length of time it supplies air or oxygen to the breathing machine. (c) The... 42 Public Health 1 2013-10-01 2013-10-01 false Service time test; open-circuit apparatus. 84.95...-Contained Breathing Apparatus § 84.95 Service time test; open-circuit apparatus. (a) Service time will be...

  19. 42 CFR 84.95 - Service time test; open-circuit apparatus.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... classified according to the length of time it supplies air or oxygen to the breathing machine. (c) The... 42 Public Health 1 2012-10-01 2012-10-01 false Service time test; open-circuit apparatus. 84.95...-Contained Breathing Apparatus § 84.95 Service time test; open-circuit apparatus. (a) Service time will be...

  20. 42 CFR 84.95 - Service time test; open-circuit apparatus.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... classified according to the length of time it supplies air or oxygen to the breathing machine. (c) The... 42 Public Health 1 2014-10-01 2014-10-01 false Service time test; open-circuit apparatus. 84.95...-Contained Breathing Apparatus § 84.95 Service time test; open-circuit apparatus. (a) Service time will be...

  1. A Grassroots Remote Sensing Toolkit Using Live Coding, Smartphones, Kites and Lightweight Drones

    PubMed Central

    Anderson, K.; Griffiths, D.; DeBell, L.; Hancock, S.; Duffy, J. P.; Shutler, J. D.; Reinhardt, W. J.; Griffiths, A.

    2016-01-01

    This manuscript describes the development of an android-based smartphone application for capturing aerial photographs and spatial metadata automatically, for use in grassroots mapping applications. The aim of the project was to exploit the plethora of on-board sensors within modern smartphones (accelerometer, GPS, compass, camera) to generate ready-to-use spatial data from lightweight aerial platforms such as drones or kites. A visual coding ‘scheme blocks’ framework was used to build the application (‘app’), so that users could customise their own data capture tools in the field. The paper reports on the coding framework, then shows the results of test flights from kites and lightweight drones and finally shows how open-source geospatial toolkits were used to generate geographical information system (GIS)-ready GeoTIFF images from the metadata stored by the app. Two Android smartphones were used in testing–a high specification OnePlus One handset and a lower cost Acer Liquid Z3 handset, to test the operational limits of the app on phones with different sensor sets. We demonstrate that best results were obtained when the phone was attached to a stable single line kite or to a gliding drone. Results show that engine or motor vibrations from powered aircraft required dampening to ensure capture of high quality images. We demonstrate how the products generated from the open-source processing workflow are easily used in GIS. The app can be downloaded freely from the Google store by searching for ‘UAV toolkit’ (UAV toolkit 2016), and used wherever an Android smartphone and aerial platform are available to deliver rapid spatial data (e.g. in supporting decision-making in humanitarian disaster-relief zones, in teaching or for grassroots remote sensing and democratic mapping). PMID:27144310

  2. Experimental studies on a new highly porous hydroxyapatite matrix for obliterating open mastoid cavities.

    PubMed

    Punke, Christoph; Zehlicke, Thorsten; Boltze, Carsten; Pau, Hans Wilhelm

    2008-09-01

    In an initial preliminary study, the applicability of a new high-porosity hydroxyapatite (HA) ceramic for obliterating large open mastoid cavities was proven and tested in an animal model (bulla of guinea pig). Experimental study. NanoBone, a highly porous matrix consisting of 76% hydroxyl apatite and 24% silicone dioxide fabricated in a sol-gel technique, was administered unilaterally into the opened bullae of 30 guinea pigs. In each animal, the opposite bulla was filled with Bio-Oss, a bone substitute consisting of a portion of mineral bovine bone. Histologic evaluations were performed 1, 2, 3, 4, 5, and 12 weeks after the implantation. After an initial phase in which the ceramic granules were surrounded by inflammatory cells (1-2 wk), there were increasing signs of vascularization. Osteoneogenesis and-at the same time-resorption of the HA ceramic were observed after the third week. No major difference in comparison to the bovine bone material could be found. Our results confirm the favorable qualities of the new ceramic reported in association with current maxillofacial literature. Conventional HA granules used for mastoid obliteration to date often showed problems with prolonged inflammatory reactions and, finally, extrusions. In contrast to those ceramics, the new material seems to induce more osteoneogenesis and undergoes early resorption probably due to its high porosity. Overall, it is similar to the bovine bone substance tested on the opposite ear in each animal. Further clinical studies may reveal whether NanoBone can be an adequate material for obliterating open mastoid cavities in patients.

  3. Cancer Prevention Fellowship Program Application Period is Open until August 25 | Division of Cancer Prevention

    Cancer.gov

    The application period for the NCI Cancer Prevention Fellowship Program (CPFP) is open. Since 1987, CPFP has provided funding support for post-doctoral Fellows to train the next generation of researchers and leaders in the field. |

  4. A Software Development Platform for Wearable Medical Applications.

    PubMed

    Zhang, Ruikai; Lin, Wei

    2015-10-01

    Wearable medical devices have become a leading trend in healthcare industry. Microcontrollers are computers on a chip with sufficient processing power and preferred embedded computing units in those devices. We have developed a software platform specifically for the design of the wearable medical applications with a small code footprint on the microcontrollers. It is supported by the open source real time operating system FreeRTOS and supplemented with a set of standard APIs for the architectural specific hardware interfaces on the microcontrollers for data acquisition and wireless communication. We modified the tick counter routine in FreeRTOS to include a real time soft clock. When combined with the multitasking features in the FreeRTOS, the platform offers the quick development of wearable applications and easy porting of the application code to different microprocessors. Test results have demonstrated that the application software developed using this platform are highly efficient in CPU usage while maintaining a small code foot print to accommodate the limited memory space in microcontrollers.

  5. Open Source, Openness, and Higher Education

    ERIC Educational Resources Information Center

    Wiley, David

    2006-01-01

    In this article David Wiley provides an overview of how the general expansion of open source software has affected the world of education in particular. In doing so, Wiley not only addresses the development of open source software applications for teachers and administrators, he also discusses how the fundamental philosophy of the open source…

  6. State-of-the-practice and lessons learned on implementing open data and open source policies.

    DOT National Transportation Integrated Search

    2012-05-01

    This report describes the current government, academic, and private sector practices associated with open data and open source application development. These practices are identified; and the potential uses with the ITS Programs Data Capture and M...

  7. Thermo-electrochemical evaluation of lithium-ion batteries for space applications

    NASA Astrophysics Data System (ADS)

    Walker, W.; Yayathi, S.; Shaw, J.; Ardebili, H.

    2015-12-01

    Advanced energy storage and power management systems designed through rigorous materials selection, testing and analysis processes are essential to ensuring mission longevity and success for space exploration applications. Comprehensive testing of Boston Power Swing 5300 lithium-ion (Li-ion) cells utilized by the National Aeronautics and Space Administration (NASA) to power humanoid robot Robonaut 2 (R2) is conducted to support the development of a test-correlated Thermal Desktop (TD) Systems Improved Numerical Differencing Analyzer (SINDA) (TD-S) model for evaluation of power system thermal performance. Temperature, current, working voltage and open circuit voltage measurements are taken during nominal charge-discharge operations to provide necessary characterization of the Swing 5300 cells for TD-S model correlation. Building from test data, embedded FORTRAN statements directly simulate Ohmic heat generation of the cells during charge-discharge as a function of surrounding temperature, local cell temperature and state of charge. The unique capability gained by using TD-S is demonstrated by simulating R2 battery thermal performance in example orbital environments for hypothetical extra-vehicular activities (EVA) exterior to a small satellite. Results provide necessary demonstration of this TD-S technique for thermo-electrochemical analysis of Li-ion cells operating in space environments.

  8. Characterization of Proxy Application Performance on Advanced Architectures. UMT2013, MCB, AMG2013

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Howell, Louis H.; Gunney, Brian T.; Bhatele, Abhinav

    2015-10-09

    Three codes were tested at LLNL as part of a Tri-Lab effort to make detailed assessments of several proxy applications on various advanced architectures, with the eventual goal of extending these assessments to codes of programmatic interest running more realistic simulations. Teams from Sandia and Los Alamos tested proxy apps of their own. The focus in this report is on the LLNL codes UMT2013, MCB, and AMG2013. We present weak and strong MPI scaling results and studies of OpenMP efficiency on a large BG/Q system at LLNL, with comparison against similar tests on an Intel Sandy Bridge TLCC2 system. Themore » hardware counters on BG/Q provide detailed information on many aspects of on-node performance, while information from the mpiP tool gives insight into the reasons for the differing scaling behavior on these two different architectures. Results from three more speculative tests are also included: one that exploits NVRAM as extended memory, one that studies performance under a power bound, and one that illustrates the effects of changing the torus network mapping on BG/Q.« less

  9. The MUSOS (MUsic SOftware System) Toolkit: A computer-based, open source application for testing memory for melodies.

    PubMed

    Rainsford, M; Palmer, M A; Paine, G

    2018-04-01

    Despite numerous innovative studies, rates of replication in the field of music psychology are extremely low (Frieler et al., 2013). Two key methodological challenges affecting researchers wishing to administer and reproduce studies in music cognition are the difficulty of measuring musical responses, particularly when conducting free-recall studies, and access to a reliable set of novel stimuli unrestricted by copyright or licensing issues. In this article, we propose a solution for these challenges in computer-based administration. We present a computer-based application for testing memory for melodies. Created using the software Max/MSP (Cycling '74, 2014a), the MUSOS (Music Software System) Toolkit uses a simple modular framework configurable for testing common paradigms such as recall, old-new recognition, and stem completion. The program is accompanied by a stimulus set of 156 novel, copyright-free melodies, in audio and Max/MSP file formats. Two pilot tests were conducted to establish the properties of the accompanying stimulus set that are relevant to music cognition and general memory research. By using this software, a researcher without specialist musical training may administer and accurately measure responses from common paradigms used in the study of memory for music.

  10. Microparticle Separation by Cyclonic Separation

    NASA Astrophysics Data System (ADS)

    Karback, Keegan; Leith, Alexander

    2017-11-01

    The ability to separate particles based on their size has wide ranging applications from the industrial to the medical. Currently, cyclonic separators are primarily used in agriculture and manufacturing to syphon out contaminates or products from an air supply. This has led us to believe that cyclonic separation has more applications than the agricultural and industrial. Using the OpenFoam computational package, we were able to determine the flow parameters of a vortex in a cyclonic separator in order to segregate dust particles to a cutoff size of tens of nanometers. To test the model, we constructed an experiment to separate a test dust of various sized particles. We filled a chamber with Arizona test dust and utilized an acoustic suspension technique to segregate particles finer than a coarse cutoff size and introduce them into the cyclonic separation apparatus where they were further separated via a vortex following our computational model. The size of the particles separated from this experiment will be used to further refine our model. Metropolitan State University of Denver, Colorado University of Denver, Dr. Randall Tagg, Dr. Richard Krantz.

  11. SedFoam-2.0: a 3-D two-phase flow numerical model for sediment transport

    NASA Astrophysics Data System (ADS)

    Chauchat, Julien; Cheng, Zhen; Nagel, Tim; Bonamy, Cyrille; Hsu, Tian-Jian

    2017-11-01

    In this paper, a three-dimensional two-phase flow solver, SedFoam-2.0, is presented for sediment transport applications. The solver is extended from twoPhaseEulerFoam available in the 2.1.0 release of the open-source CFD (computational fluid dynamics) toolbox OpenFOAM. In this approach the sediment phase is modeled as a continuum, and constitutive laws have to be prescribed for the sediment stresses. In the proposed solver, two different intergranular stress models are implemented: the kinetic theory of granular flows and the dense granular flow rheology μ(I). For the fluid stress, laminar or turbulent flow regimes can be simulated and three different turbulence models are available for sediment transport: a simple mixing length model (one-dimensional configuration only), a k - ɛ, and a k - ω model. The numerical implementation is demonstrated on four test cases: sedimentation of suspended particles, laminar bed load, sheet flow, and scour at an apron. These test cases illustrate the capabilities of SedFoam-2.0 to deal with complex turbulent sediment transport problems with different combinations of intergranular stress and turbulence models.

  12. Investigation on the accuracy and reliability of in-situ stress measurements using hydraulic fracturing in perforated cased holes

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Warpinski, N.R.

    At present, the only viable technique for accurately measuring stresses at depth in a borehole is hydraulic fracturing. These have been termed microfracs because very small amounts of fluid are injected at low flow rates into the formation. When the well is shut in, the pressure immediately drops from the injection pressure to the instantaneous shut-in pressure (ISIP) which is approximately equal to sigma/sub min/. In general, the ISIP can be measured quite accurately in open holes. For most oil and gas applications, however, it is impossible or impractical to conduct these tests in an open-hole environment. The effects ofmore » the casing, cement annulus, explosive perforation damage, and random performation orientation are impossible to predict theoretically, and laboratory tests are usually conducted under nonrealistic conditions. A set of in situ experiments was conducted to evaluate the accuracy and reliability of this technique, to aid in the selection of an optimum perforation schedule, and to develop a diagnostic capability from the pressure response.« less

  13. An HTML Tool for Production of Interactive Stereoscopic Compositions.

    PubMed

    Chistyakov, Alexey; Soto, Maria Teresa; Martí, Enric; Carrabina, Jordi

    2016-12-01

    The benefits of stereoscopic vision in medical applications were appreciated and have been thoroughly studied for more than a century. The usage of the stereoscopic displays has a proven positive impact on performance in various medical tasks. At the same time the market of 3D-enabled technologies is blooming. New high resolution stereo cameras, TVs, projectors, monitors, and head mounted displays become available. This equipment, completed with a corresponding application program interface (API), could be relatively easy implemented in a system. Such complexes could open new possibilities for medical applications exploiting the stereoscopic depth. This work proposes a tool for production of interactive stereoscopic graphical user interfaces, which could represent a software layer for web-based medical systems facilitating the stereoscopic effect. Further the tool's operation mode and the results of the conducted subjective and objective performance tests will be exposed.

  14. Development of high-average-power DPSSL with high beam quality

    NASA Astrophysics Data System (ADS)

    Nakai, Sadao; Kanabe, Tadashi; Kawashima, Toshiyuki; Yamanaka, Masanobu; Izawa, Yasukazu; Nakatuka, Masahiro; Kandasamy, Ranganathan; Kan, Hirofumi; Hiruma, Teruo; Niino, Masayuki

    2000-08-01

    The recent progress of high power diode laser is opening new fields of laser and its application. We are developing high average power diode pumped solid state laser DPSSL for laser fusion power plant, for space propulsion and for various applications in industry. The common features or requirements of our High Average-power Laser for Nuclear-fusion Application (HALNA) are large pulse energy with relatively low repetition of few tens Hz, good beam quality of order of diffraction limit and high efficiency more than 10%. We constructed HALNA 10 (10J X 10 Hz) and tested the performance to clarify the scalability to higher power system. We have obtained in a preliminary experiment a 8.5 J output energy at 0.5 Hz with beam quality of 2 times diffraction limited far-field pattern.

  15. Composite turbine blade design options for Claude (open) cycle OTEC power systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Penney, T R

    1985-11-01

    Small-scale turbine rotors made from composites offer several technical advantages for a Claude (open) cycle ocean thermal energy conversion (OTEC) power system. Westinghouse Electric Corporation has designed a composite turbine rotor/disk using state-of-the-art analysis methods for large-scale (100-MW/sub e/) open cycle OTEC applications. Near-term demonstrations using conventional low-pressure turbine blade shapes with composite material would achieve feasibility and modern credibility of the open cycle OTEC power system. Application of composite blades for low-pressure turbo-machinery potentially improves the reliability of conventional metal blades affected by stress corrosion.

  16. Toward Enhancing OpenMP's Work-Sharing Directives

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chapman, B M; Huang, L; Jin, H

    2006-05-17

    OpenMP provides a portable programming interface for shared memory parallel computers (SMPs). Although this interface has proven successful for small SMPs, it requires greater flexibility in light of the steadily growing size of individual SMPs and the recent advent of multithreaded chips. In this paper, we describe two application development experiences that exposed these expressivity problems in the current OpenMP specification. We then propose mechanisms to overcome these limitations, including thread subteams and thread topologies. Thus, we identify language features that improve OpenMP application performance on emerging and large-scale platforms while preserving ease of programming.

  17. Investigating the Feasibility and Utility of Bedside Balance Technology Acutely After Pediatric Concussion: A Pilot Study.

    PubMed

    Rhine, Tara D; Byczkowski, Terri L; Clark, Ross A; Babcock, Lynn

    2016-05-01

    To examine postural instability in children acutely after concussion, using the Wii Balance Board (WBB). We hypothesized that children with traumatic brain injury would have significantly worse balance relative to children without brain injury. Prospective case-control pilot study. Emergency department of a tertiary urban pediatric hospital. Cases were a convenience sample 11-16 years old who presented within 6 hours of sustaining concussion. Two controls, matched on gender, height, and age, were enrolled for each case that completed study procedures. Controls were children who presented for a minor complaint that was unlikely to affect balance. Not applicable. The participant's postural sway expressed as the displacement in centimeters of the center of pressure during a timed balance task. Balance testing was performed using 4 stances (single or double limb, eyes open or closed). Three of the 17 (17.6%) cases were too dizzy to complete testing. One stance, double limbs eyes open, was significantly higher in cases versus controls (85.6 vs 64.3 cm, P = 0.04). A simple test on the WBB consisting of a 2-legged standing balance task with eyes open discriminated children with concussion from non-head-injured controls. The low cost and feasibility of this device make it a potentially viable tool for assessing postural stability in children with concussion for both longitudinal research studies and clinical care. These pilot data suggest that the WBB is an inexpensive tool that can be used on the sideline or in the outpatient setting to objectively identify and quantify postural instability.

  18. Bio-Inspired Controller on an FPGA Applied to Closed-Loop Diaphragmatic Stimulation

    PubMed Central

    Zbrzeski, Adeline; Bornat, Yannick; Hillen, Brian; Siu, Ricardo; Abbas, James; Jung, Ranu; Renaud, Sylvie

    2016-01-01

    Cervical spinal cord injury can disrupt connections between the brain respiratory network and the respiratory muscles which can lead to partial or complete loss of ventilatory control and require ventilatory assistance. Unlike current open-loop technology, a closed-loop diaphragmatic pacing system could overcome the drawbacks of manual titration as well as respond to changing ventilation requirements. We present an original bio-inspired assistive technology for real-time ventilation assistance, implemented in a digital configurable Field Programmable Gate Array (FPGA). The bio-inspired controller, which is a spiking neural network (SNN) inspired by the medullary respiratory network, is as robust as a classic controller while having a flexible, low-power and low-cost hardware design. The system was simulated in MATLAB with FPGA-specific constraints and tested with a computational model of rat breathing; the model reproduced experimentally collected respiratory data in eupneic animals. The open-loop version of the bio-inspired controller was implemented on the FPGA. Electrical test bench characterizations confirmed the system functionality. Open and closed-loop paradigm simulations were simulated to test the FPGA system real-time behavior using the rat computational model. The closed-loop system monitors breathing and changes in respiratory demands to drive diaphragmatic stimulation. The simulated results inform future acute animal experiments and constitute the first step toward the development of a neuromorphic, adaptive, compact, low-power, implantable device. The bio-inspired hardware design optimizes the FPGA resource and time costs while harnessing the computational power of spike-based neuromorphic hardware. Its real-time feature makes it suitable for in vivo applications. PMID:27378844

  19. Scaling law in free walking of mice in circular open fields of various diameters.

    PubMed

    Shoji, Hiroto

    2016-03-01

    Open-field tests are routinely used to study locomotor activity in rodents. I studied the effects of apparatus size on rodent locomotor activity, specifically with respect to how resting and walking periods are interwoven. I explored the open-field behavior of mice utilizing circular open fields of various diameters. When the diameter of the test apparatus was greater than 75 cm, the durations of the resting and moving periods of free walking behavior obeyed bounded power-law distribution functions. I found that the properties of the scaling exponents and model selection became similar for test apparatus diameters greater than 75 cm. These results can provide a guide for the selection of the size of the test apparatus for use in the study of the open-field behavior of rodents.

  20. Reliability and engineering sciences area. Materials research: Single junction thin film

    NASA Technical Reports Server (NTRS)

    1986-01-01

    A test bench was designed and fabricated for the purpose of improving control of hot-spot test accuracy. Electrochemical corrosion research focused on corrosion mechanisms to which both crystalline and a-Si modules may be subjected in central station applications. A variety of cells and several designs were subjected to accelerated stress tests. Humiditiy degradation rates were determined and key electrochemical failure mechanisms were identified. Software was developed for the prediction of power loss resulting from open circuits in an array field of a-Si modules. Failure analysis was continued on the four ARCO Solar Genesis modules. The interactions of water on the silicon module was examined. An autocatalytic photooxidation model was proposed. The reliability and durability of bonding materials and electrical insulation were also studied.

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