Sample records for operating environment coe

  1. Information Operations Team Training & Information Operations Training Aid, Information Warfare Effectiveness (IWE) Program, Delivery Order 8

    DTIC Science & Technology

    2010-03-01

    submenus and toolbar with icon buttons 4. The IFOTA shall conform to Defense Information Infrastructure Common Operating Environment ( DII COE) and...him my business card , but it might come in the package we request via AFRL). PSYOP Instructor IWST is now called IWT (??) SME MD MD Instructor...Engineering and Software Engineering CTA Cognitive Task Analysis DII COE Defense Information Infrastructure Common Operating Environment EJB Enterprise Java

  2. Photogrammetric point cloud compression for tactical networks

    NASA Astrophysics Data System (ADS)

    Madison, Andrew C.; Massaro, Richard D.; Wayant, Clayton D.; Anderson, John E.; Smith, Clint B.

    2017-05-01

    We report progress toward the development of a compression schema suitable for use in the Army's Common Operating Environment (COE) tactical network. The COE facilitates the dissemination of information across all Warfighter echelons through the establishment of data standards and networking methods that coordinate the readout and control of a multitude of sensors in a common operating environment. When integrated with a robust geospatial mapping functionality, the COE enables force tracking, remote surveillance, and heightened situational awareness to Soldiers at the tactical level. Our work establishes a point cloud compression algorithm through image-based deconstruction and photogrammetric reconstruction of three-dimensional (3D) data that is suitable for dissimination within the COE. An open source visualization toolkit was used to deconstruct 3D point cloud models based on ground mobile light detection and ranging (LiDAR) into a series of images and associated metadata that can be easily transmitted on a tactical network. Stereo photogrammetric reconstruction is then conducted on the received image stream to reveal the transmitted 3D model. The reported method boasts nominal compression ratios typically on the order of 250 while retaining tactical information and accurate georegistration. Our work advances the scope of persistent intelligence, surveillance, and reconnaissance through the development of 3D visualization and data compression techniques relevant to the tactical operations environment.

  3. 32 CFR 536.9 - Responsibilities and operations of area claims offices.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... construction activities, the Chief Counsel, COE, may require that a COE ACO forward claims through COE channels... 32 National Defense 3 2014-07-01 2014-07-01 false Responsibilities and operations of area claims... CLAIMS AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES The Army Claims System § 536.9 Responsibilities and...

  4. 32 CFR 536.9 - Responsibilities and operations of area claims offices.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... construction activities, the Chief Counsel, COE, may require that a COE ACO forward claims through COE channels... 32 National Defense 3 2010-07-01 2010-07-01 true Responsibilities and operations of area claims... CLAIMS AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES The Army Claims System § 536.9 Responsibilities and...

  5. 32 CFR 536.9 - Responsibilities and operations of area claims offices.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... construction activities, the Chief Counsel, COE, may require that a COE ACO forward claims through COE channels... 32 National Defense 3 2013-07-01 2013-07-01 false Responsibilities and operations of area claims... CLAIMS AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES The Army Claims System § 536.9 Responsibilities and...

  6. 32 CFR 536.9 - Responsibilities and operations of area claims offices.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... construction activities, the Chief Counsel, COE, may require that a COE ACO forward claims through COE channels... 32 National Defense 3 2011-07-01 2009-07-01 true Responsibilities and operations of area claims... CLAIMS AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES The Army Claims System § 536.9 Responsibilities and...

  7. 32 CFR 536.9 - Responsibilities and operations of area claims offices.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... construction activities, the Chief Counsel, COE, may require that a COE ACO forward claims through COE channels... 32 National Defense 3 2012-07-01 2009-07-01 true Responsibilities and operations of area claims... CLAIMS AND ACCOUNTS CLAIMS AGAINST THE UNITED STATES The Army Claims System § 536.9 Responsibilities and...

  8. Systemic Operational Design: An Alternative to Estimate Planning

    DTIC Science & Technology

    2009-05-04

    relationships found in the COE. Framing and campaign design, with emphasis on systems theory , have therefore made their way to the forefront of doctrinal...short explanation of the systems theory behind SOD, examines how the SOD process happens, and compares SOD with the time proven “Commander’s Estimate... Theory , Campaign planning, Contemporary Operating Environment, Commander’s Estimate Process, Operational design 16. SECURITY CLASSIFICATION OF

  9. A Space Surveillance Ontology: Captured in an XML Schema

    DTIC Science & Technology

    2000-10-01

    characterization in a way most appropriate to a sub- domain. 6. The commercial market is embracing XML, and the military can take advantage of this significant...the space surveillance ontology effort to two key efforts: the Defense Information Infrastructure Common Operating Environment (DII COE) XML...strongly believe XML schemas will supplant them. Some of the advantages that XML schemas provide over DTDs include: • Strong data typing: The XML Schema

  10. Policy recommendations for rare disease centres of expertise.

    PubMed

    Syed, Ahmed M; Camp, Rob; Mischorr-Boch, Christina; Houÿez, Francois; Aro, Arja R

    2015-10-01

    Rare diseases are a serious public health concern and are a priority in the EU. This study aims to develop policy recommendations for rare disease centres of expertise (CoEs) in order to improve standards and quality of care. A modified 3-round Delphi technique was used. Participants included rare diseases patients, carers, patient representatives and healthcare professionals (HCPs) from CoEs in two countries-Denmark and the UK. The results suggest the need to make improvements within current CoE environments, access to CoEs and the need for coordination and cooperation of services within and outside CoEs. It is recommended that CoEs are not overly 'medicalised', while at the same time they should be established as research facilities. The importance of including patient representatives in CoE performance management was also highlighted. Raising awareness and provision of appropriate training amongst non-specialist HCPs is seen as a priority for early and correct diagnosis and ensuring high quality care. Similarly, provision of targeted information about patients' illness and care was considered essential along with access to social assistance within CoEs. Policy recommendations were developed in areas previously recognised as having gaps. Their implementation is expected to strengthen and improve current care provision for rare disease patients. In member states where national plans and strategies are being developed, it is recommended to replicate the methodological approach used in this study as it has proven to be a helpful tool in rare disease centres of expertise policy development. Copyright © 2015 Elsevier Ltd. All rights reserved.

  11. Center of Excellence to build nursing scholarship and improve health care in Italy.

    PubMed

    Rocco, Gennaro; Affonso, Dyanne; Mayberry, Linda; Sasso, Loredana; Stievano, Alessandro; Alvaro, Rosaria

    2015-03-01

    This article profiles the establishment and initial phase (2010-2014) of a Center of Excellence (CoE) as an instrument to strengthen nursing scholarship and improve health care in Italy. This CoE is unique as a non-university-based center. The National Regulatory Board of Registered Nurses, Health Visitors, and Pediatric Nurses (IPASVI) designated substantial administrative and funding support to the CoE for advancing nursing education, clinical practice, research development, and research training. Boyer's Model of Scholarship underpinned the CoE's conceptual framework, and its operational infrastructure was adapted from the U.S. National Institutes of Health P20 program award mechanism. Diverse methods included sponsoring research studies by nurse-led teams, research training courses, nursing education longitudinal studies, evidence-based practice training, and related pilot studies. Multiple collaborative projects were conducted via the CoE in conjunction with the successful launch of an expansive digital library and communication system accessible to nurses. The introduction of English proficiency courses was also a unique contribution. The CoE concept is a potential instrument to strengthen nursing scholarship in Italy with potential scalability considerations to other global settings. An overlapping focus on research, education, and practice under the umbrella of nursing scholarship within a CoE while engaging all levels of nursing is important to impact healthcare changes. © 2015 Sigma Theta Tau International.

  12. A Framework for Evaluating Common Operating Environments: Piloting, Lessons Learned, and Opportunities

    DTIC Science & Technology

    2011-02-01

    run a Microsoft OS. Apple iTunes Online sales and distribution of streaming and stored entertain- ment content www.itunes.com Apple provides the...Apple iTunes Online sales and distribu- tion of streaming and stored entertainment con- tent PodCast Creator Podcast Creator provides integrated...Commercial examples of software system COEs include Cisco WebEx, Microsoft NetMeet- CMU/SEI-2010-SR-025 | 16 ing, and Apple iTunes . Example Problem Space

  13. Changing the Army’s Weapon Training Strategies to Meet Operational Requirements More Efficiently and Effectively

    DTIC Science & Technology

    2014-01-01

    System Maneuver COe M4/16 Rifle M9 pistol M2 , MK19, and M240B Machine Guns , M249 Squad Automatic Rifle Bradley Fighting Vehicle Abrams Tank Fires COe 155mm...27 Rifle, Machine Gun , and SAW Training...are called desig- nated weapons. For example, a maintenance company may have some machine guns authorized for self-protection that are manned by

  14. Why Not Airdrop? The Utility of Preplanned Airdrop to Resupply Land Forces in the Contemporary Operating Environment

    DTIC Science & Technology

    2006-05-25

    AMLOs ). ALOs and AMLOs are rated United States Air Force pilots or navigators former from the fighter and or bomber community and the latter from the...the final ground--air link in close air support. For airdrop, AMLOs have the expertise to assist Army units with planning and coordination.139 Given...the dispersed nature of the COE, however, the one or two AMLOs assigned to each rce to be tapped into is the ETACs. These Airmen not only “speak

  15. Assessing engineering students' demonstration of workplace competencies in experiential learning environments through internships and cooperative work experiences

    NASA Astrophysics Data System (ADS)

    Laingen, Mark A.

    This study investigates the relationships between supervisor assessments and internship students' self-assessments for 15 workplace competencies, demonstrated in an internship or cooperative work environment. The 15 workplace competencies were developed by Iowa State University in collaboration with over 200 constituents comprised of Iowa State University COE alumni, engineering employers, COE faculty, partnering international faculty, and COE students, to provide clear, independent, and assessable measures for the eleven learning outcomes identified in the ABET Criterion 3 (a-k) outcomes. The study investigated workplace competency assessment data collected over ten years, commencing with the fall 2001 internship assessment term and concluding with the fall 2011 assessment term. The study used three separate methodologies to analyze workplace competency assessments in the COE. Part 1 analyzed data across the fifteen workplace competencies, and across ten programs in the College of Engineering, that have been involved with the workplace competency assessment of internship and cooperative students from the beginning of data collection in 2001. Supervisor assessment ratings were compared to internship student self-assessment ratings across the ten-year span from 2001-11using the non-parametric equivalent of the paired t-test; the Wilcoxon singed rank test for paired data. Part 2 of the study investigated the relationship between supervisor and student self-assessment data across assessment terms related to the 2001-05 and 2006-11 ABET accreditation cycles. The third part investigated how data tracking workplace competency strengths and weaknesses and ABET outcomes achievement percentages have changed between the assessment terms across accreditation cycles. Part 3 included an on-line survey sent to program curriculum committee members involved with workplace competency assessment data that investigated how the engineering programs are utilizing this data in support of continuous improvement of the program curricula. Results of the analysis demonstrate how paired supervisor assessment and student self-assessment ratings for assessment of the internship students' demonstration of workplace competencies can be useful in evaluating student demonstration of competency in COE learning outcomes through the experiential learning environment, and support continuous improvement practices for program curriculum development.

  16. Oral Delivery of Probiotics Expressing Dendritic Cell-Targeting Peptide Fused with Porcine Epidemic Diarrhea Virus COE Antigen: A Promising Vaccine Strategy against PEDV.

    PubMed

    Wang, Xiaona; Wang, Li; Huang, Xuewei; Ma, Sunting; Yu, Meiling; Shi, Wen; Qiao, Xinyuan; Tang, Lijie; Xu, Yigang; Li, Yijing

    2017-10-25

    Porcine epidemic diarrhea virus (PEDV), an enteric coronavirus, is the causative agent of porcine epidemic diarrhea (PED) that damages intestinal epithelial cells and results in severe diarrhea and dehydration in neonatal suckling pigs with up to 100% mortality. The oral vaccine route is reported as a promising approach for inducing protective immunity against PEDV invasion. Furthermore, dendritic cells (DCs), professional antigen-presenting cells, link humoral and cellular immune responses for homeostasis of the intestinal immune environment. In this study, in order to explore an efficient oral vaccine against PEDV infection, a mucosal DC-targeting oral vaccine was developed using Lactobacillus casei to deliver the DC-targeting peptide (DCpep) fused with the PEDV core neutralizing epitope (COE) antigen. This probiotic vaccine could efficiently elicit secretory immunoglobulin A (SIgA)-based mucosal and immunoglobulin G (IgG)-based humoral immune responses via oral vaccination in vivo. Significant differences ( p < 0.05) in the immune response levels were observed between probiotics expressing the COE-DCpep fusion protein and COE antigen alone, suggesting better immune efficiency of the probiotics vaccine expressing the DC-targeting peptide fused with PEDV COE antigen. This mucosal DC-targeting oral vaccine delivery effectively enhances vaccine antigen delivery efficiency, providing a useful strategy to induce efficient immune responses against PEDV infection.

  17. Department of Defense Joint Technical Architecture Version 2.0

    DTIC Science & Technology

    1998-05-26

    Mandates 2.1-5 2.1.4.1 Year 2000 (Y2K) Compliance 2.1-5 2.1.4.2 Defense Information Infrastructure Common Operating Environment (DU COE) 2.1-5 2.1.5...2.2.2.2.1.6 Communications Services 2.2-11 2.2.2.2.1.7 Operating System Services 2.2-11 2.2.2.2.2 Application Platform Cross-Area Services 2.2- 12 ...2.2.2.2.2.1 Internationalization Services 2.2- 12 2.2.2.2.2.2 Security Services 2.2- 12 2.2.2.2.2.3 System Management Services 2.2- 12 2.2.2.2.2.4

  18. The new emergency structure of the Istituto Nazionale di Geofisica e Vulcanologia during the L’Aquila 2009 seismic sequence: the contribution of the COES (Seismological Emergency Operation Center - Centro Operativo Emergenza Sismica)

    NASA Astrophysics Data System (ADS)

    Moretti, M.; Govoni, A.; Nostro, C.; La Longa, F.; Crescimbene, M.; Pignone, M.; Selvaggi, G.; Working Group, C.

    2009-12-01

    The Centro Nazionale Terremoti (CNT - National Earthquake Center), departement of Istituto Nazionale di Geofisica e Vulcanologia (INGV), has designed and setup a rapid response emergency structure to face the occurrence of strong earthquakes. This structure is composed by a real time satellite telemetered temporary seismic network (see Abruzzese et al., 2009 Fall AGU) used to improve the hypocentral locations of the INGV National Seismic Network, a stand alone temporary seismic network whose goal is primarily the high dynamic/high resolution data acquisition in the epicentral area and a mobile operational center, the COES (Centro Operativo Emergenza Sismica, Seismological Emergency Operational Center). The COES structure is a sort of mobile office equipped with satellite internet communication that can be rapidly installed in the disaster area to support all the INGV staff operative needs and to cooperate with the Civil Protection department (DPC) aggregating all the scientific information available on the seismic sequence and providing updated information to Civil Protection for the decision making stage during the emergency. The structure is equipped with a heavy load trolley that carries a 6x6 inflatable tent, a satellite router, an UPS, computers, monitors and furniture. The facility can be installed in a couple of hours in the epicentral area and provides a full featured office with dedicated internet connection and VPN access to the INGV data management center in Rome. Just after the April 6 2009 Mw 6.3 earthquake in L’Aquila (Central Italy) the COES has been installed upon request of the Italian Civil Protection (DPC) in the DICOMAC (Directorate of Command and Control - which is the central structure of the DPC that coordinates the emergency activities in the areas affected by the earthquake) located in the Guardia di Finanza headquarters in Coppito nearby L'Aquila (the same location that hosted the G8 meeting). The COES produces real time reports on the seismic sequence evolution constituted by a detailed sequence map, histograms showing the evolution of the magnitude and the number of earthquakes in time and a daily event list. Moreover, it is possible to see the real time hypocentral locations using “SISMAP” (Doumaz et al., 2008), the same tool used in the Seismic Monitoring Center in Rome. During the emergency the COES has been also a reference information point for all people involved in the crisis management and has provided also psychological support to the rescuers and to the earthquake affected population. This education and outreach activity has proved to be extremely effective. References Abruzzese L. et al., AGU Fall Meeting 2009. Doumaz F. et al., Geomedia, speciale geologia, pp. 10-13, 2008.

  19. M and S supporting unmanned autonomous systems (UAxS) concept development and experimentation

    NASA Astrophysics Data System (ADS)

    Biagini, Marco; Scaccianoce, Alfio; Corona, Fabio; Forconi, Sonia; Byrum, Frank; Fowler, Olivia; Sidoran, James L.

    2017-05-01

    The development of the next generation of multi-domain unmanned semi and fully autonomous C4ISR systems involves a multitude of security concerns and interoperability challenges. Conceptual solutions to capability shortfalls and gaps can be identified through Concept Development and Experimentation (CD and E) cycles. Modelling and Simulation (M and S) is a key tool in supporting unmanned autonomous systems (UAxS) CD and E activities and addressing associated security challenges. This paper serves to illustrate the application of M and S to UAxS development and highlight initiatives made by the North Atlantic Treaty Organization (NATO) M and S Centre of Excellence (CoE) to facilitate interoperability. The NATO M and S CoE collaborates with other NATO and Nations bodies in order to develop UAxS projects such as the Allied Command for Transformation Counter Unmanned Autonomous Systems (CUAxS) project or the work of Science and Technology Organization (STO) panels. Some initiatives, such as Simulated Interactive Robotics Initiative (SIRI) made the baseline for further developments and to study emerging technologies in M and S and robotics fields. Artificial Intelligence algorithm modelling, Robot Operating Systems (ROS), network operations, cyber security, interoperable languages and related data models are some of the main aspects considered in this paper. In particular, the implementation of interoperable languages like C-BML and NIEM MilOps are discussed in relation to a Command and Control - Simulation Interoperability (C2SIM) paradigm. All these technologies are used to build a conceptual architecture to support UAxS CD and E.In addition, other projects that the NATO M and S CoE is involved in, such as the NATO Urbanization Project could provide credible future operational environments and benefit UAxS project development, as dual application of UAxS technology in large urbanized areas.In conclusion, this paper contains a detailed overview regarding how applying Modelling and Simulation to support CD and E activities is a valid approach to develop and validate future capabilities requirements in general and next generation UAxS.

  20. COE loss-of-function analysis reveals a genetic program underlying maintenance and regeneration of the nervous system in planarians.

    PubMed

    Cowles, Martis W; Omuro, Kerilyn C; Stanley, Brianna N; Quintanilla, Carlo G; Zayas, Ricardo M

    2014-10-01

    Members of the COE family of transcription factors are required for central nervous system (CNS) development. However, the function of COE in the post-embryonic CNS remains largely unknown. An excellent model for investigating gene function in the adult CNS is the freshwater planarian. This animal is capable of regenerating neurons from an adult pluripotent stem cell population and regaining normal function. We previously showed that planarian coe is expressed in differentiating and mature neurons and that its function is required for proper CNS regeneration. Here, we show that coe is essential to maintain nervous system architecture and patterning in intact (uninjured) planarians. We took advantage of the robust phenotype in intact animals to investigate the genetic programs coe regulates in the CNS. We compared the transcriptional profiles of control and coe RNAi planarians using RNA sequencing and identified approximately 900 differentially expressed genes in coe knockdown animals, including 397 downregulated genes that were enriched for nervous system functional annotations. Next, we validated a subset of the downregulated transcripts by analyzing their expression in coe-deficient planarians and testing if the mRNAs could be detected in coe+ cells. These experiments revealed novel candidate targets of coe in the CNS such as ion channel, neuropeptide, and neurotransmitter genes. Finally, to determine if loss of any of the validated transcripts underscores the coe knockdown phenotype, we knocked down their expression by RNAi and uncovered a set of coe-regulated genes implicated in CNS regeneration and patterning, including orthologs of sodium channel alpha-subunit and pou4. Our study broadens the knowledge of gene expression programs regulated by COE that are required for maintenance of neural subtypes and nervous system architecture in adult animals.

  1. Stresses and pressures at the quartz-coesite transition in shear experiments

    NASA Astrophysics Data System (ADS)

    Richter, B.; Stunitz, H.; Heilbronner, R.

    2015-12-01

    Experiments on quartz (qtz) gouge were performed in a Griggs-type deformation apparatus at displacement rates of ~1.3 x 10-5 mms-1 or ~1.3 x 10-4 mms-1, at Pc= 1.0 GPa or 1.5 GPa and T = 600°C to 800°C. The starting material is a natural hydrothermally grown single crystal that was crushed to a powder with grain size d < 100 µm. Coesite (coe) is found if the maximum principle stress (σ1) is in the coe stability field. In general Pc and the mean stress (Pm) of these samples are below the quartz-coesite phase transition (QCT). Coe is not found if σ1 is below the QCT. At T = 600 °C, σ1is always in the coe stability field. But coe is only present in the high strain experiment, indicating slow transformation kinetics. In one sample we observed that σ1crosses the QCT during the loading part and after progressive weakening crosses the QCT back into the qtz stability field. The microstructure of this sample shows the formation of coe and the reverse transformation from coe to qtz. The coe growth penetrates the sample and coe grows around and in between larger qtz clasts. At high stresses, where Pm is also above the QCT, coe often forms radiating aggregates. At lower stresses, where only σ1 lies in the stability field of coe, and at low strain the coe grains have a preferred orientation of the b-axes (sub-) parallel to σ1. With increasing strain, the rigid coe grains rotate and align with the preferred qtz fabric. For coe to be found, it is sufficient that σ1 reaches values above the transformation pressure. If σ1 drops back into the qtz stability field during an experiment, a back-reaction from coe to qtz is observed. It appears therefore that the pressure that defines the QCT is not Pc or Pm, but σ1.

  2. ADA Integrated Environment III. System Specification.

    DTIC Science & Technology

    1981-12-01

    different from Report) Same ’S. SUPPLEMENTARY NOTES RADC Project Engineer: Elizabeth S. Kean (COES) 19. KEY WORDS (Cortinue an reverse s,do if...is a (ollection of programs associated with the Ada Integrated Environment instead of a particular user. When the AlE is bru (Jht tip on a machine, the

  3. Stanford/NASA-Ames Center of Excellence in model-based human performance

    NASA Technical Reports Server (NTRS)

    Wandell, Brian A.

    1990-01-01

    The human operator plays a critical role in many aeronautic and astronautic missions. The Stanford/NASA-Ames Center of Excellence in Model-Based Human Performance (COE) was initiated in 1985 to further our understanding of the performance capabilities and performance limits of the human component of aeronautic and astronautic projects. Support from the COE is devoted to those areas of experimental and theoretical work designed to summarize and explain human performance by developing computable performance models. The ultimate goal is to make these computable models available to other scientists for use in design and evaluation of aeronautic and astronautic instrumentation. Within vision science, two topics have received particular attention. First, researchers did extensive work analyzing the human ability to recognize object color relatively independent of the spectral power distribution of the ambient lighting (color constancy). The COE has supported a number of research papers in this area, as well as the development of a substantial data base of surface reflectance functions, ambient illumination functions, and an associated software package for rendering and analyzing image data with respect to these spectral functions. Second, the COE supported new empirical studies on the problem of selecting colors for visual display equipment to enhance human performance in discrimination and recognition tasks.

  4. 77 FR 59667 - NIJ Evaluation of Through-Wall Sensor Devices

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-09-28

    ..., Surveillance, and Biometric Technologies Center of Excellence (SSBT CoE). The evaluation is focused on field operation in civilian law enforcement scenarios. Supplied through-wall sensor devices must be fully certified by the Federal Communications Commission for domestic civilian law enforcement operation...

  5. Navy MANTECH 2008 Project Book

    DTIC Science & Technology

    2008-01-01

    work center. The project team kept statistics on the actual operations in that work center and assessed the fidelity of those operations with...base, a power- ful analytic and predictive capability, and a database of validated industry best practices. The BMPCOE- developed Collaborative Work ...Today, the EMPF operates as a national electronics manufacturing COE focused on the development , application and

  6. The importance of consumption of the epidermis in malignant melanoma and correlation with clinicopathological prognostic parameters.

    PubMed

    Seçkin, Selda; Ozgũn, Elmas

    2011-01-01

    The aim of the study was to investigate the importance of consumption of the epidermis as an additional diagnostic criteria for malignant melanoma and to evaluate its relationship to clinicopathological findings. The age, gender, localization of the lesion and the histopathological parameters such as tumor type, Breslow thickness, ulceration, Clark's level, mitosis/mm2, lymphocytic infiltration were noted in 40 malignant melanoma cases. Consumption of the epidermis was evaluated in tumor sections. Consumption of the epidermis (COE) due to thinning of the epidermis and loss of rete ridges was noted as (+) or (-). Furthermore, COE was compared with clinical and histopathological parameters. The Shapiro Wilk and Logistic Regression tests were used for statistical analysis. The results were accepted as significant if the p value was < 0.05. COE was detected in 60% (24/40) of malignant melanoma cases. A positive correlation was present between COE and head and neck localization (p = 0,698), superficial spreading melanoma (p = 0,341), ulceration (p = 0,097) and brisk lymphocytic infiltration (p = 0,200) but the results were not statistically significant. COE was frequently detected in males but the difference was not statistically significant (p = 0.796). There was no correlation or significant statistical association between COE and age, Breslow thickness, Clark's level or the mitotic index. The detection of COE in most of the patients suggests that COE could be a histopathological criterion in the diagnosis of malignant melanoma. The frequent association between COE and the presence of ulceration could also direct attention to COE as regards prognostic importance.

  7. Chemically Functionalized Conjugated Oligoelectrolyte Nanoparticles for Enhancement of Current Generation in Microbial Fuel Cells.

    PubMed

    Zhao, Cui-e; Chen, Jia; Ding, Yuanzhao; Wang, Victor Bochuan; Bao, Biqing; Kjelleberg, Staffan; Cao, Bin; Loo, Say Chye Joachim; Wang, Lianhui; Huang, Wei; Zhang, Qichun

    2015-07-08

    Water-soluble conjugated oligoelectrolyte nanoparticles (COE NPs), consisting of a cage-like polyhedral oligomeric silsesquioxanes (POSS) core equipped at each end with pendant groups (oligo(p-phenylenevinylene) electrolyte, OPVE), have been designed and demonstrated as an efficient strategy in increasing the current generation in Escherichia coli microbial fuel cells (MFCs). The as-prepared COE NPs take advantage of the structure of POSS and the optical properties of the pendant groups, OPVE. Confocal laser scanning microscopy showed strong photoluminescence of the stained cells, indicating spontaneous accumulation of COE NPs within cell membranes. Moreover, the electrochemical performance of the COE NPs is superior to that of an established membrane intercommunicating COE, DSSN+ in increasing current generation, suggesting that these COE NPs thus hold great potential to boost the performance of MFCs.

  8. Benefits of Two Turbine Rotor Diameters and Hub Heights in the Same Wind Farm

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dykes, Katherine L; Stanley, Andrew P. J.; Ning, Andrew

    Significant turbine-wake interactions greatly reduce power output in a wind farm. If different turbine hub heights and rotor diameters are included in the same wind farm, the wake interference in the farm will be reduced, resulting in a lower cost of energy (COE) than a farm with identical turbines. In this paper, we present a method to model wind farm COE in farms with hub heights and rotor diameters that vary across the wind farm. We also demonstrate how to optimize these wind farms to minimize COE. The results show that COE can be greatly reduced in wind farms withmore » non-homogeneous turbines, especially when the turbines are spaced close together. For a unidirectional wind rose, including different turbine design in the wind farm has a similar decrease in COE to spreading the wind turbines farther apart. When the rotor diameter and hub height of the wind turbines in a farm are optimized uniformly, a COE decrease of 4% to 13% (depending on the grid spacing and wind shear exponent) is achieved compared to the baseline. When the rotor diameter and turbine heights are optimized non-uniformly, with two different diameters and heights throughout the farm, there is a COE decrease of 22% to 41% compared to the baseline. For a more spread wind rose with a dominant probability from the west, there is a COE decrease between 3% and 10% for uniformly optimized rotor diameter and height compared to the baseline. With two optimized rotor diameters and heights through the farm, a COE decrease of 3% to 19% is achieved. For a similar wind rose shifted such that the dominant wind direction is from the northwest, a COE decrease between 3% and 10% results from uniformly optimized wind turbines compared to the baseline. A COE decrease of 3% to 17% compared to the baseline occurs with two different turbines are optimized throughout the wind farm.« less

  9. Increased risk of chronic obstructive pulmonary diseases in coke oven workers: interaction between occupational exposure and smoking

    PubMed Central

    Hu, Y; Chen, B; Yin, Z; Jia, L; Zhou, Y; Jin, T

    2006-01-01

    Background Coke oven workers are regularly exposed to coke oven emissions (COE) and may be at risk of developing lung diseases. There is limited evidence for the link between exposure to COE and chronic obstructive pulmonary diseases (COPD). The aim of this study was to explore the dose‐response relationship between COE exposure and COPD and to assess the interaction with cigarette smoking. Methods Seven hundred and twelve coke oven workers and 211 controls were investigated in southern China. Benzene soluble fraction (BSF) concentrations as a surrogate of COE were measured in representative personal samples and the individual cumulative COE exposure level was quantitatively estimated. Detailed information on smoking habits and respiratory symptoms was collected and spirometric tests were performed. Results The mean BSF levels at the top of two coking plants were 743.8 and 190.5 μg/m3, respectively, which exceed the OSHA standard (150 μg/m3). After adjusting for cigarette smoking and other risk factors, there was a significant dose‐dependent reduction in lung function and increased risks of chronic cough/phlegm and COPD in coke oven workers. The odds ratio for COPD was 5.80 (95% confidence interval 3.13 to 10.76) for high level cumulative COE exposure (⩾1714.0 μg/m3‐years) compared with controls. The interaction between COE exposure and smoking in COPD was significant. The risk of COPD in those with the highest cumulative exposure to COE and cigarette smoking was 58‐fold compared with non‐smokers not exposed to COE. Conclusion Long term exposure to COE increases the risk of an interaction between COPD and cigarette smoking. PMID:16467069

  10. COE inhibits vasculogenic mimicry in hepatocellular carcinoma via suppressing Notch1 signaling.

    PubMed

    Jue, Chen; Min, Zhao; Zhisheng, Zhang; Lin, Cui; Yayun, Qian; Xuanyi, Wang; Feng, Jin; Haibo, Wang; Youyang, Shi; Tadashi, Hisamitsu; Shintaro, Ishikawa; Shiyu, Guo; Yanqing, Liu

    2017-08-17

    Vasculogenic mimicry (VM) has been suggested to be present in various malignant tumors and associated with tumor nutrition supply and metastasis, leading to poor prognosis of patients. Notch1 has been demonstrated to contribute to VM formation in hepathocellular carcinoma (HCC). Celastrus orbiculatus extract (COE), a mixture of 11 terpenoids isolated from the Chinese Herb Celastrus orbiculatus Vine, has been suggested to be effective in cancer treatment. In the current study, experiments were carried out to examine the effect of COE on VM formation and HCC tumor growth both in vitro and in vivo. CCK-8 assay and Nikon live-work station were used to observe the viability of malignant cells treated with COE. Cell invasion was examined using Transwell. Matrigel was used to establish a 3-D culture condition for VM formation. Changes of mRNA and protein expression were examined by RT-PCR and Western Blot respectively. Tumor growth in vivo was monitored using in vivo fluorescence imaging device. PAS-CD34 dual staining and electron microscopy were used to observe VM formation. Immunohistochemical staining (IHC) was used to examine Notch1 and Hes1 expression in tumor tissues. Results showed that COE can inhibit HCC cells proliferation and invasion in a concentration-dependent manner. VM formation induced by TGF-β1 was blocked by COE. In mouse xenograft model, COE inhibited tumor growth and VM formation. Both in vitro and in vivo studies showed that COE can downregulate expression of Notch1 and Hes1. The current results indicate that COE can inhibit VM formation and HCC tumor growth by downregulating Notch1 signaling. This study demonstrates that COE is superior to other anti-angiogenesis agents and can be considered as a promising candidate in HCC treatment. Copyright © 2017 Elsevier Ireland Ltd. All rights reserved.

  11. The National Children's Study: Recruitment Outcomes Using an Enhanced Household-Based Approach.

    PubMed

    Blaisdell, Laura L; Zellner, Jennifer A; King, Alison A; Faustman, Elaine; Wilhelm, Mari; Hudak, Mark L; Annett, Robert D

    2016-06-01

    Ten National Children's Study (NCS) study locations with diverse demographic characteristics used an enhanced household-based recruitment (EHBR) approach to enroll preconceptional and pregnant women. Study centers used different types and dosages of community outreach and engagement (COE) activities and supplemental strategies. The goal of the study was to determine whether variability in enumeration and recruitment outcomes correlated with study location characteristics or types and dosages of COE activities (number of COE events, number of advance household mailings, total media expenditures, and total COE expenditures). Each of the sites provided data on COE activities, protocol implementation, supplemental recruitment activities, location demographic characteristics, and enumeration/recruitment outcomes. COE activities varied across sites in breadth and scope. Numerous strategies were used, including media advertising, social media, participation in community-wide events, presentations to stakeholders, and creation of advisory boards. Some sites included supplemental recruitment efforts. EHBR sites enrolled 1404 women at the initial pregnancy screening. No significant relationships were found between study location demographic characteristics or between the types and dosages of COE activities and recruitment outcomes. Probability sampling for a long-term study requires a positive image with stakeholders and within communities; this requirement may be especially true for door-to-door recruitment. EHBR sites successfully recruited a representative sample of preconceptional and pregnant women. Sites reported implementing similar COE activities but with varying dosage and cost; however, analyses did not support a benefit of COE strategies on study recruitment. Copyright © 2016 by the American Academy of Pediatrics.

  12. Joint Improvised Explosive Device Defeat Organization, FY 2009

    DTIC Science & Technology

    2010-01-01

    per incident, IEDs were 14 percent more effective in FY 2009 over FY 2008. Coupled with the significant corresponding increase in IED incidents...Development Testing and Evaluation (RDT&E), procurement, and sustainment of 69 systems. Detect Air Detect Air systems enable the warfighter to detect...Service-oriented centers of excellence (COE): the Army COE at Fort Irwin; the Navy COE at Indian Head, Maryland; the Air Force COE at Lackland Air

  13. ERATOSTHENES: excellence research Centre for Earth surveillance and space-based monitoring of the environment, the EXCELSIOR Horizon 2020 teaming project

    NASA Astrophysics Data System (ADS)

    Hadjimitsis, Diofantos G.; Kontoes, Haris; Schreier, Gunter; Ansmann, Albert; Komodromos, George; Themistocleous, Kyriacos; Mamouri, Rodanthi; Michaelides, Silas; Nisantzi, Argyro; Papoutsa, Christiana; Neocleous, Kyriacos; Mettas, Christodoulos; Tzouvaras, Marios; Evagorou, Evagoras; Christofe, Andreas; Melillos, George; Papoutsis, Ioannis

    2017-10-01

    The aim of this paper is to present the strategy and vision to upgrade the existing ERATOSTHENES Research Centre (ERC) established within the Cyprus University of Technology (CUT) into a sustainable, viable and autonomous Centre of Excellence (CoE) for Earth Surveillance and Space-Based Monitoring of the Environment, which will provide the highest quality of related services on the National, European and International levels. EXCELSIOR is a Horizon 2020 Teaming project which addresses a specific challenge defined by the work program, namely, the reduction of substantial disparities in the European Union by supporting research and innovation activities and systems in low performing countries. It also aims at establishing long-term and strategic partnerships between the Teaming partners, thus reducing internal research and innovation disparities within European Research and Innovation landscape. The proposed CoE envisions the upgrading of the existing ERC into an inspiring environment for conducting basic and applied research and innovation in the areas of the integrated use of remote sensing and space-based techniques for monitoring the environment. Environment has been recognized by the Smart Specialization Strategy of Cyprus as the first horizontal priority for future growth of the island. The foreseen upgrade will regard the expansion of this vision to systematic monitoring of the environment using Earth Observation, space and ground based integrated technologies. Such an approach will lead to the systematic monitoring of all three domains of the Environment (Air, Land, Water). Five partners have united to upgrade the existing ERC into a CoE, with the common vision to become a world-class innovation, research and education centre, actively contributing to the European Research Area (ERA). More specifically, the Teaming project is a team effort between the Cyprus University of Technology (CUT, acting as the coordinator), the German Aerospace Centre (DLR), the National Observatory of Athens (NOA), the German Leibniz Institute for Tropospheric Research (TROPOS) and the Cyprus Department of Electronic Communications of the Ministry of Transport, Communications and Works (DEC-MTCW).

  14. Joint Improved Explosive Device Defeat Organization. Annual Report FY 2009

    DTIC Science & Technology

    2009-01-01

    incident, IEDs were 14 percent more effective in FY 2009 over FY 2008. Coupled with the significant corresponding increase in IED incidents, this...Testing and Evaluation (RDT&E), procurement, and sustainment of 69 systems. Detect Air Detect Air systems enable the warfighter to detect insurgent...oriented centers of excellence (COE): the Army COE at Fort Irwin; the Navy COE at Indian Head, Maryland; the Air Force COE at Lackland Air Force

  15. Experience With Direct-to-Patient Recruitment for Enrollment Into a Clinical Trial in a Rare Disease: A Web-Based Study

    PubMed Central

    2017-01-01

    Background The target sample size for clinical trials often necessitates a multicenter (center of excellence, CoE) approach with associated added complexity, cost, and regulatory requirements. Alternative recruitment strategies need to be tested against this standard model. Objectives The aim of our study was to test whether a Web-based direct recruitment approach (patient-centric, PC) using social marketing strategies provides a viable option to the CoE recruitment method. Methods PC recruitment and Web-based informed consent was compared with CoE recruitment for a randomized controlled trial (RCT) of continuing versus stopping low-dose prednisone for maintenance of remission of patients with granulomatosis with polyangiitis (GPA). Results The PC approach was not as successful as the CoE approach. Enrollment of those confirmed eligible by their physician was 10 of 13 (77%) and 49 of 51 (96%) in the PC and CoE arms, respectively (P=.05). The two approaches were not significantly different in terms of eligibility with 34% of potential participants in the CoE found to be ineligible as compared with 22% in the PC arm (P=.11) nor in provider acceptance, 22% versus 26% (P=.78). There was no difference in the understanding of the trial as reflected in the knowledge surveys of individuals in the PC and CoE arms. Conclusions PC recruitment was substantially less successful than that achieved by the CoE approach. However, the PC approach was good at confirming eligibility and was as acceptable to providers and as understandable to patients as the CoE approach. The PC approach should be evaluated in other clinical settings to get a better sense of its potential. PMID:28246067

  16. Fluorescence and confocal imaging of mammalian cells using conjugated oligoelectrolytes with phenylenevinylene core

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Milczarek, Justyna; Pawlowska, Roza; Zurawinski, Remigiusz

    Over the last few years, considerable efforts are taken, in order to find a molecular fluorescent probe fulfilling their applicability requirements. Due to a good optical properties and affinity to biological structures conjugated oligoelectrolytes (COEs) can be considered as a promising dyes for application in fluorescence-based bioimaging. In this work, we synthetized COEs with phenylenevinylene core (PV-COEs) and applied as fluorescent membranous-specific probes. Cytotoxicity effects of each COE were probed on cancerous and non-cancerous cell types and little to no toxicity effects were observed at the high range of concentrations. The intensity of cell fluorescence following the COE staining wasmore » determined by the photoluminescence analysis and fluorescence activated cell sorting method (FACS). Intercalation of tested COEs into mammalian cell membranes was revealed by fluorescent and confocal microscopy colocalization with commercial dyes specific for cellular structures including mitochondria, Golgi apparatus and endoplasmic reticulum. The phenylenevinylene conjugated oligoelectrolytes have been found to be suitable for fluorescent bioimaging of mammalian cells and membrane-rich organelles. Due to their water solubility coupled with spontaneous intercalation into cells, favorable photophysical features, ease of cell staining, low cytotoxicity and selectivity for membranous structures, PV-COEs can be applied as markers for fluorescence imaging of a variety of cell types.« less

  17. PREFACE: International Conference on Advanced Structural and Functional Materials Design 2008

    NASA Astrophysics Data System (ADS)

    Kakeshita, Tomoyuki

    2009-07-01

    The Ministry of Education, Culture, Sports, Science and Technology of Japan started the Priority Assistance for the Formation of Worldwide Renowned Centers of Research - Global COE Program. This program is based on the competitive principle where a third party evaluation decides which program to support and to give priority support to the formation of world-class centers of research. Our program Center of Excellence for Advanced Structural and Functional Materials Design was selected as one of 13 programs in the field of Chemistry and Materials Science. This center is composed of two materials-related Departments in the Graduate School of Engineering: Materials and Manufacturing Science and Adaptive Machine Systems, and 4 Research Institutes: Center for Atomic and Molecular Technologies, Welding and Joining Research Institute, Institute of Scientific and Industrial Research and Research Center for Ultra-High Voltage Electron Microscopy. Recently, materials research, particularly that of metallic materials, has specialized only in individual elemental characteristics and narrow specialty fields, and there is a feeling that the original role of materials research has been forgotten. The 6 educational and research organizations which make up the COE program cooperatively try to develop new advanced structural and functional materials and achieve technological breakthrough for their fabrication processes from electronic, atomic, microstructural and morphological standpoints, focusing on their design and application: development of high performance structural materials such as space plane and turbine blades operating under a severe environment, new fabrication and assembling methods for electronic devices, development of evaluation technique for materials reliability, and development of new biomaterials for regeneration of biological hard tissues. The aim of this international conference was to report the scientific progress in our Global COE program and also to discuss related research topics. The organizing committee gratefully thanks participants for presenting their recent results and for discussions with our COE members and international attendees. November 2008 Professor Tomoyuki Kakeshita Chairman of the Conference Vice Dean, Graduate School of Engineering, Osaka University, Division of Materials and Manufacturing Science, Graduate School of Engineering Leader of Global COE Program, Osaka University, ''Center of Excellence for Advanced Structural and Functional Materials Design'' Organization Chairman: T Kakeshita (Osaka University) Advisory Board:H Mehrer (University Münster, Germany), E K H Salje (University of Cambridge, United Kingdom), H-E Schaefer (University of Stuttgart, Germany), P Veyssiere (CNRS-ONERA, France) Organizing Committee: T Kakeshita, H Araki, H Fujii, S Fujimoto, Y Fujiwara, A Hirose, S Kirihara, M Mochizuki, H Mori, T Nagase, H Nakajima, T Nakano, R Nakatani, K Nogi, Y Setsuhara, Y Shiratsuchi, T Tanaka, T Terai, H Tsuchiya, N Tsuji, H Utsunomiya, H Yasuda, H Yasuda (Osaka University) Executive Committee: T Kakeshita, S Fujimoto, Y Fujiwara, A Hirose, T Tanaka, H Yasuda (Osaka University) Conference Secretariat: Y Fujiwara (Osaka University) Proceedings Editors: T Kakeshita and Y Fujiwara (Osaka University) Conference photograph

  18. Injury and illness in college outdoor education.

    PubMed

    Gaudio, Flavio G; Greenwald, Peter W; Holton, Mark

    2010-12-01

    Many colleges offer outdoor education courses such as rock climbing, kayaking, and mountain biking. Since these sports may be perceived as dangerous, we describe the prevalence of injuries and illnesses in a large, university-based outdoor education program. We also compare composite incident rates from this outdoor program to those of traditional college sports. Cohort of college students participating in either Cornell Outdoor Education (COE) or National Collegiate Athletic Association (NCAA) sports and comparison of incident rates. COE data were prospectively collected in the field; and NCAA data were prospectively collected through the Association's Injury Surveillance System. By definition, a COE injury or illness required follow-up care, prescription medication, or limited course participation. Similarly, a NCAA injury limited further practice or play. Incident rates were calculated as injuries and illnesses per 1000 participant-days (COE) or injuries per 1000 athlete-exposures (NCAA). Included COE courses during 2002-2007 totaled 74 005 participant-days. There were 111 injuries and illnesses, rate = 1.50/1000 participant-days (95% CI 1.24-1.81). The NCAA reported 32 646 899 athlete-exposures during 1988-2004 and 181 476 injuries, rate = 5.56/1000 athlete-exposures (95% CI 5.53-5.58). Compared to COE, the relative risk of injury in NCAA sports was 3.7 (95% CI 3.1-4.5) overall and 3.3 (95% CI 2.8-4.0) after excluding the high-contact sports of football, ice hockey, and wrestling. For COE, mountain biking had the highest incident rate (7.5/1000), which was significantly lower than game injury rates in NCAA football and soccer. The most common injuries for both NCAA and COE were soft-tissue injuries such as sprains and strains. Outdoor education at this university-sponsored program was at least as safe as traditional college sports. Overall, college students were less likely to be injured while participating in COE courses than while participating in NCAA sports, even after excluding high-contact sports from the comparison. Copyright © 2010. Published by Elsevier Inc.

  19. Annotation and expression of carboxylesterases in the silkworm, Bombyx mori.

    PubMed

    Yu, Quan-You; Lu, Cheng; Li, Wen-Le; Xiang, Zhong-Huai; Zhang, Ze

    2009-11-24

    Carboxylesterase is a multifunctional superfamily and ubiquitous in all living organisms, including animals, plants, insects, and microbes. It plays important roles in xenobiotic detoxification, and pheromone degradation, neurogenesis and regulating development. Previous studies mainly used Dipteran Drosophila and mosquitoes as model organisms to investigate the roles of the insect COEs in insecticide resistance. However, genome-wide characterization of COEs in phytophagous insects and comparative analysis remain to be performed. Based on the newly assembled genome sequence, 76 putative COEs were identified in Bombyx mori. Relative to other Dipteran and Hymenopteran insects, alpha-esterases were significantly expanded in the silkworm. Genomics analysis suggested that BmCOEs showed chromosome preferable distribution and 55% of which were tandem arranged. Sixty-one BmCOEs were transcribed based on cDNA/ESTs and microarray data. Generally, most of the COEs showed tissue specific expressions and expression level between male and female did not display obvious differences. Three main patterns could be classified, i.e. midgut-, head and integument-, and silk gland-specific expressions. Midgut is the first barrier of xenobiotics peroral toxicity, in which COEs may be involved in eliminating secondary metabolites of mulberry leaves and contaminants of insecticides in diet. For head and integument-class, most of the members were homologous to odorant-degrading enzyme (ODE) and antennal esterase. RT-PCR verified that the ODE-like esterases were also highly expressed in larvae antenna and maxilla, and thus they may play important roles in degradation of plant volatiles or other xenobiotics. B. mori has the largest number of insect COE genes characterized to date. Comparative genomic analysis suggested that the gene expansion mainly occurred in silkworm alpha-esterases. Expression evidence indicated that the expanded genes were specifically expressed in midgut, integument and head, implying that these genes may have important roles in detoxifying secondary metabolites of mulberry leaves, contaminants in diet, and odorants. Our results provide some new insights into functions and evolutionary characteristics of COEs in phytophagous insects.

  20. Annotation and expression of carboxylesterases in the silkworm, Bombyx mori

    PubMed Central

    2009-01-01

    Background Carboxylesterase is a multifunctional superfamily and ubiquitous in all living organisms, including animals, plants, insects, and microbes. It plays important roles in xenobiotic detoxification, and pheromone degradation, neurogenesis and regulating development. Previous studies mainly used Dipteran Drosophila and mosquitoes as model organisms to investigate the roles of the insect COEs in insecticide resistance. However, genome-wide characterization of COEs in phytophagous insects and comparative analysis remain to be performed. Results Based on the newly assembled genome sequence, 76 putative COEs were identified in Bombyx mori. Relative to other Dipteran and Hymenopteran insects, alpha-esterases were significantly expanded in the silkworm. Genomics analysis suggested that BmCOEs showed chromosome preferable distribution and 55% of which were tandem arranged. Sixty-one BmCOEs were transcribed based on cDNA/ESTs and microarray data. Generally, most of the COEs showed tissue specific expressions and expression level between male and female did not display obvious differences. Three main patterns could be classified, i.e. midgut-, head and integument-, and silk gland-specific expressions. Midgut is the first barrier of xenobiotics peroral toxicity, in which COEs may be involved in eliminating secondary metabolites of mulberry leaves and contaminants of insecticides in diet. For head and integument-class, most of the members were homologous to odorant-degrading enzyme (ODE) and antennal esterase. RT-PCR verified that the ODE-like esterases were also highly expressed in larvae antenna and maxilla, and thus they may play important roles in degradation of plant volatiles or other xenobiotics. Conclusion B. mori has the largest number of insect COE genes characterized to date. Comparative genomic analysis suggested that the gene expansion mainly occurred in silkworm alpha-esterases. Expression evidence indicated that the expanded genes were specifically expressed in midgut, integument and head, implying that these genes may have important roles in detoxifying secondary metabolites of mulberry leaves, contaminants in diet, and odorants. Our results provide some new insights into functions and evolutionary characteristics of COEs in phytophagous insects. PMID:19930670

  1. 32 CFR 643.4 - Responsibilities of the Chief of Engineers (COE).

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 32 National Defense 4 2011-07-01 2011-07-01 false Responsibilities of the Chief of Engineers (COE... (CONTINUED) REAL PROPERTY REAL ESTATE General § 643.4 Responsibilities of the Chief of Engineers (COE). (a... estate will be delegated, to the extent feasible, to U.S. Army Division and District Engineers (DE). (e...

  2. 32 CFR 643.4 - Responsibilities of the Chief of Engineers (COE).

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 32 National Defense 4 2014-07-01 2013-07-01 true Responsibilities of the Chief of Engineers (COE... (CONTINUED) REAL PROPERTY REAL ESTATE General § 643.4 Responsibilities of the Chief of Engineers (COE). (a... estate will be delegated, to the extent feasible, to U.S. Army Division and District Engineers (DE). (e...

  3. 32 CFR 643.4 - Responsibilities of the Chief of Engineers (COE).

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 32 National Defense 4 2013-07-01 2013-07-01 false Responsibilities of the Chief of Engineers (COE... (CONTINUED) REAL PROPERTY REAL ESTATE General § 643.4 Responsibilities of the Chief of Engineers (COE). (a... estate will be delegated, to the extent feasible, to U.S. Army Division and District Engineers (DE). (e...

  4. 32 CFR 643.4 - Responsibilities of the Chief of Engineers (COE).

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 32 National Defense 4 2012-07-01 2011-07-01 true Responsibilities of the Chief of Engineers (COE... (CONTINUED) REAL PROPERTY REAL ESTATE General § 643.4 Responsibilities of the Chief of Engineers (COE). (a... estate will be delegated, to the extent feasible, to U.S. Army Division and District Engineers (DE). (e...

  5. 32 CFR 643.4 - Responsibilities of the Chief of Engineers (COE).

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Responsibilities of the Chief of Engineers (COE... (CONTINUED) REAL PROPERTY REAL ESTATE General § 643.4 Responsibilities of the Chief of Engineers (COE). (a... estate will be delegated, to the extent feasible, to U.S. Army Division and District Engineers (DE). (e...

  6. Experience With Direct-to-Patient Recruitment for Enrollment Into a Clinical Trial in a Rare Disease: A Web-Based Study.

    PubMed

    Krischer, Jeffrey; Cronholm, Peter F; Burroughs, Cristina; McAlear, Carol A; Borchin, Renee; Easley, Ebony; Davis, Trocon; Kullman, Joyce; Carette, Simon; Khalidi, Nader; Koening, Curry; Langford, Carol A; Monach, Paul; Moreland, Larry; Pagnoux, Christian; Specks, Ulrich; Sreih, Antoine G; Ytterberg, Steven; Merkel, Peter A

    2017-02-28

    The target sample size for clinical trials often necessitates a multicenter (center of excellence, CoE) approach with associated added complexity, cost, and regulatory requirements. Alternative recruitment strategies need to be tested against this standard model. The aim of our study was to test whether a Web-based direct recruitment approach (patient-centric, PC) using social marketing strategies provides a viable option to the CoE recruitment method. PC recruitment and Web-based informed consent was compared with CoE recruitment for a randomized controlled trial (RCT) of continuing versus stopping low-dose prednisone for maintenance of remission of patients with granulomatosis with polyangiitis (GPA). The PC approach was not as successful as the CoE approach. Enrollment of those confirmed eligible by their physician was 10 of 13 (77%) and 49 of 51 (96%) in the PC and CoE arms, respectively (P=.05). The two approaches were not significantly different in terms of eligibility with 34% of potential participants in the CoE found to be ineligible as compared with 22% in the PC arm (P=.11) nor in provider acceptance, 22% versus 26% (P=.78). There was no difference in the understanding of the trial as reflected in the knowledge surveys of individuals in the PC and CoE arms. PC recruitment was substantially less successful than that achieved by the CoE approach. However, the PC approach was good at confirming eligibility and was as acceptable to providers and as understandable to patients as the CoE approach. The PC approach should be evaluated in other clinical settings to get a better sense of its potential. ©Jeffrey Krischer, Peter F Cronholm, Cristina Burroughs, Carol A McAlear, Renee Borchin, Ebony Easley, Trocon Davis, Joyce Kullman, Simon Carette, Nader Khalidi, Curry Koening, Carol A Langford, Paul Monach, Larry Moreland, Christian Pagnoux, Ulrich Specks, Antoine G Sreih, Steven Ytterberg, Peter A Merkel, Vasculitis Clinical Research Consortium. Originally published in the Journal of Medical Internet Research (http://www.jmir.org), 28.02.2017.

  7. A system-level cost-of-energy wind farm layout optimization with landowner modeling

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Chen, Le; MacDonald, Erin

    This work applies an enhanced levelized wind farm cost model, including landowner remittance fees, to determine optimal turbine placements under three landowner participation scenarios and two land-plot shapes. Instead of assuming a continuous piece of land is available for the wind farm construction, as in most layout optimizations, the problem formulation represents landowner participation scenarios as a binary string variable, along with the number of turbines. The cost parameters and model are a combination of models from the National Renewable Energy Laboratory (NREL), Lawrence Berkeley National Laboratory, and Windustiy. The system-level cost-of-energy (COE) optimization model is also tested under twomore » land-plot shapes: equally-sized square land plots and unequal rectangle land plots. The optimal COEs results are compared to actual COE data and found to be realistic. The results show that landowner remittances account for approximately 10% of farm operating costs across all cases. Irregular land-plot shapes are easily handled by the model. We find that larger land plots do not necessarily receive higher remittance fees. The model can help site developers identify the most crucial land plots for project success and the optimal positions of turbines, with realistic estimates of costs and profitability. (C) 2013 Elsevier Ltd. All rights reserved.« less

  8. Organic extracts of coke oven emissions can induce genetic damage in metabolically competent HepG2 cells.

    PubMed

    Xin, Lili; Wang, Jianshu; Guo, Sifan; Wu, Yanhu; Li, Xiaohai; Deng, Huaxin; Kuang, Dan; Xiao, Wei; Wu, Tangchun; Guo, Huan

    2014-05-01

    Coke oven emissions (COEs) containing various carcinogenic polycyclic aromatic hydrocarbons (PAHs) represent the coal-burning pollution in the air. Organic pollutants in the aerosol and particulate matter of COEs were collected from the bottom, side, and top of a coke oven. The Comet assay and cytokinesis-block micronucleus cytome assay were conducted to analyze the genetic damage of extractable organic matter (EOM) of COEs on HepG2 cells. All the three EOMs could induce significant dose-dependent increases in Olive tail moment, tail DNA, and tail length, micronuclei, nucleoplasmic bridges, and nuclear buds frequencies, which were mostly positively correlated with the total PAHs concentration in each EOM. In conclusion, EOMs of COEs in the three typical working places of coke oven can induce DNA strand breaks and genomic instability in the metabolically competent HepG2 cells. The PAHs in EOMs may be important causative agents for the genotoxic effects of COEs. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Instructional Design Briefing A Brief Overview in Relation to the China COE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Osburn, Laura Ann; Glasco, Bethany Lynn

    This introduction provides a roadmap and guidance for the work that will be done by SMEs to prepare NDA course material to be transitioned from LANL to the China COE. It will cover the definition of instructional design; why instructional design is important; role of instructional designer vs an instructor and how they work together; and how this relates to our work in the China COE project.

  10. Center of Excellence in Model-Based Human Performance

    NASA Technical Reports Server (NTRS)

    Wandell, Brian A.

    1997-01-01

    The Center of Excellence (COE) was created in 1984 to facilitate active collaboration between the scientists at Ames Research Center and the Stanford Psychology Department. As this document will review, over that period of time, the COE served its function well. Funds from the Center supported a large number of projects over the last ten years. Many of the people who were supported by the Center have gone on to distinguished research careers in government, industry and university. In fact, several of the people currently working at NASA Ames were initially funded by the Center mechanism, which served as a useful vehicle for attracting top quality candidates and supporting their research efforts. We are grateful for NASA's support over the years. As we reviewed in the reports for each year, the COE budget generally provided a portion of the true costs of the individual research projects. Hence, the funds from the COE were leveraged with funds from industry and other government agencies. In this way, we feel that all parties benefitted greatly from the collaborative spirit and interactive aspects of the COE. The portion of the support from NASA was particularly important in helping members of the COE to set aside the time to publish papers and communicate advances in our understanding of human performance in NASA-related missions.

  11. Center of Excellence in Model-Based Human Performance

    NASA Technical Reports Server (NTRS)

    Wandell, Brian A.

    1997-01-01

    The Center of Excellence (COE) was created in 1984 to facilitate active collaboration between the scientists at Ames Research Center and the Stanford Psychology Department. As this document will review, over that period of time, the COE served its function well. Funds from the Center supported a large number of projects over the last ten years. Many of the people who were supported by the Center Have gone on to distinguished research careers in government, industry and university. In fact, several of the people currently working at NASA Ames were initially funded by the Center mechanism, which served as a useful vehicle for attracting top quality candidates and supporting their research efforts. We are grateful for NASA's support over the years. As we reviewed in the reports for each year, the COE budget generally provided a portion of the true costs of the individual research project. Hence, the funds from the COE were leveraged with funds from industry and other government agencies. In this way, we feel that all parties benefitted greatly from the collaborative spirit and interactive aspects of the COE. The portion of the support from NASA was particularly important in helping members of the COE to set aside the time to publish papers and communicate advances in our understanding of human performance in NASA-related missions.

  12. Science Outreach for the Thousands: Coe College's Playground of Science

    NASA Astrophysics Data System (ADS)

    Watson, D. E.; Franke, M.; Affatigato, M.; Feller, S.

    2011-12-01

    Coe College is a private liberal arts college nestled in the northeast quadrant of Cedar Rapids, IA. Coe takes pride in the outreach it does in the local community. The sciences at Coe find enjoyment in educating the children and families of this community through a diverse set of venues; from performing science demonstrations for children at Cedar Rapids' Fourth of July Freedom Festival to hosting summer forums and talks to invigorate the minds of its more mature audiences. Among these events, the signature event of the year is the Coe Playground of Science. On the last Thursday of October, before Halloween, the science departments at Coe invite nearly two thousand children from pre elementary to high school ages, along with their parents to participate in a night filled with science demos, haunted halls, and trick-or-treating for more than just candy. The demonstrations are performed by professors and students alike from a raft of cooperative departments including physics, chemistry, biology, math, computer science, nursing, ROTC, and psychology. This event greatly strengthens the relationships between institution members and community members. The sciences at Coe understand the importance of imparting the thrill and hunger for exploration and discovery into the future generations. More importantly they recognize that this cannot start and end at the collegiate level, but the American public must be reached at younger ages and continue to be encouraged beyond the college experience. The Playground of Science unites these two groups under the common goal of elevating scientific interest in the American people.

  13. 50 CFR 635.31 - Restrictions on sale and purchase.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... permit for shark if that vessel fishes exclusively in state waters. Dealers may purchase a sandbar shark... Certificate of Eligibility (COE) form, obtained from NMFS, or its equivalent that documents that the fish was... buying and selling. (c) Shark. (1) Persons that own or operate a vessel that possesses a shark from the...

  14. 50 CFR 635.31 - Restrictions on sale and purchase.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... permit for shark if that vessel fishes exclusively in state waters. Dealers may purchase a sandbar shark... Certificate of Eligibility (COE) form, obtained from NMFS, or its equivalent that documents that the fish was... buying and selling. (c) Shark. (1) Persons that own or operate a vessel that possesses a shark from the...

  15. Aquatic Biological Inventory, Hillview Drainage and Levee District, Greene and Scott Counties, Illinois.

    DTIC Science & Technology

    1982-01-11

    generally influence taxa more or less uniformly. Rotifers are more adaptable to lotic environments, whereas cladocerans and copepods are more prolific in...organisms adapted to soft substrate environments, such as oligochaetes, were not present in the samples. Macroinvertebrate diversity values ranged from...Cr% 44 In-O In-O .CC c~ UU Cuu -A (N 057 COE-IIAS-S. /bSC4. 14 1/10/82 collections at this site were composed of epibenthic forms adapted to riffle

  16. Training the Neglected Core of Army Leadership- Troop-Leading Procedures

    DTIC Science & Technology

    2007-06-01

    tactical operations center ( TOC ) to reconnoiter, using the MDMP to complete their plans, etc. TLP are considered procedures, and the Army’s previous...and establishing an effective and responsive Prevention of Sexual Haras- sment (POSH)/Equal Opportunity (EO) program. Since dedicated citizen...8. One unit posted signs all over its TOC that read, “Who else needs to know!” 03A - COE/Full-Spectrum Operations/Why We Fight 03C - Perform Cultural

  17. [Using the stable HSPA1A promoter-driven luciferase reporter HepG2 cells to assess the overall toxicity of coke oven emissions].

    PubMed

    Xin, Li-li; Li, Xiao-hai; Deng, Hua-xin; Kuang, Dan; Dai, Xia-yun; Huang, Su-Li; Wang, Feng; He, Mei-an; Currie, R William; Wu, Tang-chun

    2012-12-01

    Using the stable HSPA1A (HSP70-1) promoter-driven luciferase reporter HepG2 cells (HepG2/HSPA1A cells) to assess the overall toxicity of coke oven emissions. The stable HepG2/HSPA1A cells were treated with different concentrations of coke oven emissions (COEs) collected from the top, side, and bottom of a coke oven battery for 24 h. After the treatments, luciferase activity, cell viability, malondialdehyde (MDA) concentration, Olive tail moment, and micronuclei frequency were determined, respectively. The bottom COEs induced significant increases (P < 0.01) in relative luciferase activity up to 1.4 times the control level at 0.15 µg/L. The low dose of side COEs (0.02 µg/L) led to a significant increase (P < 0.01) in relative luciferase activity that progressively increased to 2.1 times the control level at 65.4 µg/L. The top COEs produced a strong dose-dependent induction of relative luciferase activity up to over 5 times the control level at the highest concentration tested (202 µg/L). In HepG2/HSPA1A cells treated with the bottom COEs, relative luciferase activity was positively correlated with MDA concentration (r = 0.404, P < 0.05). For the three COEs samples, positive correlations were observed between relative luciferase activity and Olive tail moment and micronuclei frequency. The relative luciferase activity in HepG2/HSPA1A cells can sensitively reflect the overall toxicity of COEs. The stable HepG2/HSPA1A cells can be used for rapid screening of the overall toxicity of complex air pollutants in the workplace.

  18. Implementation Plan for the NASA Center of Excellence for Structures and Materials

    NASA Technical Reports Server (NTRS)

    Harris, Charles E. (Editor)

    1998-01-01

    This report presents the implementation plans of the Center of Excellence (COE) for Structures and Materials. The plan documented herein is the result of an Agencywide planning activity led by the Office of the Center of Excellence for Structures and Materials at Langley Research Center (LaRC). The COE Leadership Team, with a representative from each NASA Field Center, was established to assist LaRC in fulfilling the responsibilities of the COE. The Leadership Team developed the plan presented in this report.

  19. Offshore wind farm layout optimization

    NASA Astrophysics Data System (ADS)

    Elkinton, Christopher Neil

    Offshore wind energy technology is maturing in Europe and is poised to make a significant contribution to the U.S. energy production portfolio. Building on the knowledge the wind industry has gained to date, this dissertation investigates the influences of different site conditions on offshore wind farm micrositing---the layout of individual turbines within the boundaries of a wind farm. For offshore wind farms, these conditions include, among others, the wind and wave climates, water depths, and soil conditions at the site. An analysis tool has been developed that is capable of estimating the cost of energy (COE) from offshore wind farms. For this analysis, the COE has been divided into several modeled components: major costs (e.g. turbines, electrical interconnection, maintenance, etc.), energy production, and energy losses. By treating these component models as functions of site-dependent parameters, the analysis tool can investigate the influence of these parameters on the COE. Some parameters result in simultaneous increases of both energy and cost. In these cases, the analysis tool was used to determine the value of the parameter that yielded the lowest COE and, thus, the best balance of cost and energy. The models have been validated and generally compare favorably with existing offshore wind farm data. The analysis technique was then paired with optimization algorithms to form a tool with which to design offshore wind farm layouts for which the COE was minimized. Greedy heuristic and genetic optimization algorithms have been tuned and implemented. The use of these two algorithms in series has been shown to produce the best, most consistent solutions. The influences of site conditions on the COE have been studied further by applying the analysis and optimization tools to the initial design of a small offshore wind farm near the town of Hull, Massachusetts. The results of an initial full-site analysis and optimization were used to constrain the boundaries of the farm. A more thorough optimization highlighted the features of the area that would result in a minimized COE. The results showed reasonable layout designs and COE estimates that are consistent with existing offshore wind farms.

  20. 32 CFR Appendix C to Part 651 - Mitigation and Monitoring

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ..., COE research laboratories, COE districts and divisions, and DoD Regional Support Centers. State... technical parameters used must be measurable; for example, the monitoring program must be quantitative and...

  1. 32 CFR Appendix C to Part 651 - Mitigation and Monitoring

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ..., COE research laboratories, COE districts and divisions, and DoD Regional Support Centers. State... technical parameters used must be measurable; for example, the monitoring program must be quantitative and...

  2. 32 CFR Appendix C to Part 651 - Mitigation and Monitoring

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ..., COE research laboratories, COE districts and divisions, and DoD Regional Support Centers. State... technical parameters used must be measurable; for example, the monitoring program must be quantitative and...

  3. 32 CFR Appendix C to Part 651 - Mitigation and Monitoring

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., COE research laboratories, COE districts and divisions, and DoD Regional Support Centers. State... technical parameters used must be measurable; for example, the monitoring program must be quantitative and...

  4. 32 CFR Appendix C to Part 651 - Mitigation and Monitoring

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ..., COE research laboratories, COE districts and divisions, and DoD Regional Support Centers. State... technical parameters used must be measurable; for example, the monitoring program must be quantitative and...

  5. Geriatric core competencies for family medicine curriculum and enhanced skills: care of elderly.

    PubMed

    Charles, Lesley; Triscott, Jean A C; Dobbs, Bonnie M; McKay, Rhianne

    2014-06-01

    There is a growing mandate for Family Medicine residency programs to directly assess residents' clinical competence in Care of the Elderly (COE). The objectives of this paper are to describe the development and implementation of incremental core competencies for Postgraduate Year (PGY)-I Integrated Geriatrics Family Medicine, PGY-II Geriatrics Rotation Family Medicine, and PGY-III Enhanced Skills COE for COE Diploma residents at a Canadian University. Iterative expert panel process for the development of the core competencies, with a pre-defined process for implementation of the core competencies. Eighty-five core competencies were selected overall by the Working Group, with 57 core competencies selected for the PGY-I/II Family Medicine residents and an additional 28 selected for the PGY-III COE residents. The core competencies follow the CanMEDS Family Medicine roles. Both sets of core competencies are based on consensus. Due to demographic changes, it is essential that Family Physicians have the required skills and knowledge to care for the frail elderly. The core competencies described were developed for PGY-I/II Family Medicine residents and PGY-III Enhanced Skills COE, with a focus on the development of geriatric expertise for those patients that would most benefit.

  6. ENVIRONMENTAL STATISTICS INITIATIVE

    EPA Science Inventory

    EPA's Center of Excellence (COE) for Environmental Computational Science is intended to integrate cutting-edge science and emerging information technology (IT) solutions for input to the decision-making process. Complementing the research goals of EPA's COE, the NERL has initiat...

  7. Facile Preparation of Drug-Loaded Tristearin Encapsulated Superparamagnetic Iron Oxide Nanoparticles Using Coaxial Electrospray Processing.

    PubMed

    Rasekh, Manoochehr; Ahmad, Zeeshan; Cross, Richard; Hernández-Gil, Javier; Wilton-Ely, James D E T; Miller, Philip W

    2017-06-05

    Naturally occurring polymers are promising biocompatible materials that have many applications for emerging therapies, drug delivery systems, and diagnostic agents. The handling and processing of such materials still constitutes a major challenge, which can limit the full exploitation of their properties. This study explores an ambient environment processing technique: coaxial electrospray (CO-ES) to encapsulate genistein (an isoflavonoid and model drug), superparamagnetic iron oxide nanoparticles (SPIONs, 10-15 nm), and a fluorophore (BODIPY) into a layered (triglyceride tristearin shell) particulate system, with a view to constructing a theranostic agent. Mode mapping of CO-ES led to an optimized atomization engineering window for stable jetting, leading to encapsulation of SPIONs within particles of diameter 0.65-1.2 μm and drug encapsulation efficiencies of around 92%. Electron microscopy was used to image the encapsulated SPIONs and confirm core-shell triglyceride encapsulation in addition to further physicochemical characterization (AFM, FTIR, DSC, and TGA). Cell viability assays (MTT, HeLa cells) were used to determine optimal SPION loaded particles (∼1 mg/mL), while in vitro release profile experiments (PBS, pH = 7.4) demonstrate a triphasic release profile. Further cell studies confirmed cell uptake and internalization at selected time points (t = 1, 2, and 4 h). The results suggest potential for using the CO-ES technique as an efficient way to encapsulate SPIONs together with sensitive drugs for the development of multimodal particles that have potential application for combined imaging and therapy.

  8. A summary of the ECAS MHD power plant results

    NASA Technical Reports Server (NTRS)

    Seikel, G. R.; Harris, L. P.

    1976-01-01

    The performance and the cost of electricity (COE) for MHD systems utilizing coal or coal derived fuels are summarized along with a conceptual open cycle MHD plant design. The results show that open cycle coal fired recuperatively preheated MHD systems have potentially one of the highest coal-pile-to-bus bar efficiencies (48.3%) and also one of the lowest COE of the systems studied. Closed cycle, inert gas systems do not appear to have the potential of exceeding the efficiency of or competing with the COE of advanced steam plants.

  9. Revised Final Environmental Review for the Construction of a New Base Exchange at Kadena Air Base, Okinawa, Japan

    DTIC Science & Technology

    2007-05-01

    factors depending on the corresponding years. Year 2005 through 2009: VOCE = .016 * Trips NOxE = .015 * Trips PM10E = .0022 * Trips COE = .262...Trips Year 2010 and beyond: VOCE = .012 * Trips NOxE = .013 * Trips PM10E = .0022 * Trips COE = .262 * Trips To convert from pounds per day to...tons per year: VOC (tons/yr) = VOCE * DPYII/2000 Nox (tons/yr) = NOxE * DPYII/2000 PM10(tons/yr) = PM10E * DPYII/2000 CO (tons/yr) = COE * DPYII

  10. Navy Explosive Ordnance Disposal School Master Development Plan for Test Area D-51, Eglin Air Force Base, Florida

    DTIC Science & Technology

    2008-01-25

    depending on the corresponding years. Year 2005 through 2009: VOCE = .016 * Trips NOxE = .015 * Trips PM10E = .0022 * Trips COE = .262 * Trips Year...2010 and beyond: VOCE = .012 * Trips NOxE = .013 * Trips PM10E = .0022 * Trips COE = .262 * Trips To convert from pounds per day to tons per year...VOC (tons/yr) = VOCE * DPYII/2000 NOx (tons/yr) = NOxE * DPYII/2000 PM10 (tons/yr) = PM10E * DPYII/2000 CO (tons/yr) = COE * DPYII/2000

  11. Genetic damage induced by organic extract of coke oven emissions on human bronchial epithelial cells.

    PubMed

    Zhai, Qingfeng; Duan, Huawei; Wang, Yadong; Huang, Chuanfeng; Niu, Yong; Dai, Yufei; Bin, Ping; Liu, Qingjun; Chen, Wen; Ma, Junxiang; Zheng, Yuxin

    2012-08-01

    Coke oven emissions are known as human carcinogen, which is a complex mixture of polycyclic aromatic hydrocarbon. In this study, we aimed to clarify the mechanism of action of coke oven emissions induced carcinogenesis and to identify biomarkers of early biological effects in a human bronchial epithelial cell line with CYP1A1 activity (HBE-CYP1A1). Particulate matter was collected in the oven area on glass filter, extracted and analyzed by GC/MS. DNA breaks and oxidative damage were evaluated by alkaline and endonucleases (FPG, hOGG1 and ENDO III)-modified comet assays. Cytotoxicity and chromosomal damage were assessed by the cytokinesis-block micronucleus cytome (CBMN-Cyt) assay. The cells were treated with organic extract of coke oven emissions (OE-COE) representing 5, 10, 20, 40μg/mL extract for 24h. We found that there was a dose-effect relationship between the OE-COE and the direct DNA damage presented by tail length, tail intensity and Olive tail moment in the comet assay. The presence of lesion-specific endonucleases in the assays increased DNA migration after OE-COE treatment when compared to those without enzymes, which indicated that OE-COE produced oxidative damage at the level of pyrimidine and purine bases. The dose-dependent increase of micronuclei, nucleoplasmic bridges and nuclear buds in exposed cells was significant, indicating chromosomal and genomic damage induced by OE-COE. Based on the cytotoxic biomarkers in CBMN-Cyt assay, OE-COE may inhibit nuclear division, interfere with apoptosis, or induce cell necrosis. This study indicates that OE-COE exposure can induce DNA breaks/oxidative damage and genomic instability in HBE-CYP1A1 cells. The FPG-comet assay appears more specific for detecting oxidative DNA damage induced by complex mixtures of genotoxic substances. Copyright © 2012 Elsevier Ltd. All rights reserved.

  12. Antithrombotic effects of ethanol extract of Crataegus orientalis in the carrageenan-induced mice tail thrombosis model.

    PubMed

    Arslan, Rana; Bor, Zeynep; Bektas, Nurcan; Meriçli, Ali Hikmet; Ozturk, Yusuf

    2011-03-01

    Crataegus species (common name is Hawthorn) are medicinal plants, which have flavonoids, triterpene acids, proanthocyanidins, and organic acids as main constituents, used in the treatment of cardiovascular diseases. One of the main causes of multiple cardiovascular diseases is intravascular thrombosis and current agents, which are used for the treatment and prevention of thrombosis, have some side effects. Therefore, new antithrombotic and thrombolytic agents are still needed. Antithrombotic function of ethanol extract of Crataegus orientalis (COE) leaves was investigated in carrageenan-induced mice tail thrombosis model. Mice were injected with 40 μl (1%) carrageenan (Type I) dissolved in physiological saline by intraplantar administration in the right hind paw. After carrageenan injection, the extract was administered at the doses of 100, 200, and 300 mg/kg. Heparin was used as a positive control (10 and 100 IU). The length of tail-thrombosis was measured at 24th, 48th, and 72nd hours. 100mg/kg COE and 10IU heparin were not significant when compared to control groups at the time interval (24-72 h) that results was obtained. At 24th hour, both 200 and 300 mg/kg of COE showed a significant antithrombotic activity (p<0.05 and p<0.01, respectively). However, 200 mg/kg COE lost its significance and there was a decrease in the significance values of 300 mg/kg COE (p<0.05) at 48 and 72 h. From these results, it was concluded that COE significantly inhibited carrageenan-induced mice tail thrombosis in vivo. Copyright © 2010. Published by Elsevier Ltd.

  13. Survey of animal welfare, animal behavior, and animal ethics courses in the curricula of AVMA Council on Education-accredited veterinary colleges and schools.

    PubMed

    Shivley, Chelsey B; Garry, Franklyn B; Kogan, Lori R; Grandin, Temple

    2016-05-15

    OBJECTIVE To explore the extent to which veterinary colleges and schools accredited by the AVMA Council on Education (COE) have incorporated specific courses related to animal welfare, behavior, and ethics. DESIGN Survey and curriculum review. SAMPLE All 49 AVMA COE-accredited veterinary colleges and schools (institutions). PROCEDURES The study consisted of 2 parts. In part 1, a survey regarding animal welfare, behavior, and ethics was emailed to the associate dean of academic affairs at all 49 AVMA COE-accredited institutions. In part 2, the curricula for the 30 AVMA COE-accredited institutions in the United States were reviewed for courses on animal behavior, ethics, and welfare. RESULTS Seventeen of 49 (35%) institutions responded to the survey of part 1, of which 10 offered a formal animal welfare course, 9 offered a formal animal behavior course, 8 offered a formal animal ethics course, and 5 offered a combined animal welfare, behavior, and ethics course. The frequency with which courses on animal welfare, behavior, and ethics were offered differed between international and US institutions. Review of the curricula for the 30 AVMA COE-accredited US institutions revealed that 6 offered a formal course on animal welfare, 22 offered a formal course on animal behavior, and 18 offered a formal course on animal ethics. CONCLUSIONS AND CLINICAL RELEVANCE Results suggested that AVMA COE-accredited institutions need to provide more formal education on animal welfare, behavior, and ethics so veterinarians can be advocates for animals and assist with behavioral challenges.

  14. A method to quantify the "cone of economy".

    PubMed

    Haddas, Ram; Lieberman, Isador H

    2018-05-01

    A non-randomized, prospective, concurrent control cohort study. The purpose of this study is to develop and evaluate a method to quantify the dimensions of the cone of economy (COE) and the energy expenditure associated with maintaining a balanced posture within the COE, scoliosis patients and compare them to matched non-scoliotic controls in a group of adult degenerative. Balance is defined as the ability of the human body to maintain its center of mass (COM) within the base of support with minimal postural sway. The cone of economy refers to the stable region of upright standing posture. The underlying assumption is that deviating outside one's individual cone challenges the balance mechanisms. Adult degenerative scoliosis (ADS) patients exhibit a variety of postural changes within their COE, involving the spine, pelvis and lower extremities, in their effort to compensate for the altered posture. Ten ADS patients and ten non-scoliotic volunteers performed a series of functional balance tests. The dimensions of the COE and the energy expenditure related to maintaining balance within the COE were measured using a human motion video capture system and dynamic surface electromyography. ADS patients presented more COM sway in the sagittal (ADS: 1.59 cm vs. H: 0.61 cm; p = 0.049) and coronal (ADS: 2.84 cm vs. H: 1.72 cm; p = 0.046) directions in comparison to the non-scoliotic control. ADS patients presented with more COM (ADS: 33.30 cm vs. H: 19.13 cm; p = 0.039) and head (ADS: 31.06 cm vs. H: 19.13 cm; p = 0.013) displacements in comparison to the non-scoliotic controls. Scoliosis patients expended more muscle activity to maintain static standing, as manifest by increased muscle activity in their erector spinae (ADS: 37.16 mV vs. H: 20.31 mV; p = 0.050), and gluteus maximus (ADS: 33.12 mV vs. H: 12.09 mV; p = 0.001) muscles. We were able to develop and evaluate a method that quantifies the COE boundaries, COM displacement, and amount of sway within the COE along with the energy expenditure for a specific patient. This method of COE measurement will enable spine care practitioners to objectively evaluate their patients in an effort to determine the most appropriate treatment options, and in objectively documenting the effectiveness of their intervention.

  15. LLNL Center of Excellence Work Items for Q9-Q10 period

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Neely, J. R.

    This work plan encompasses a slice of effort going on within the ASC program, and for projects utilizing COE vendor resources, describes work that will be performed by both LLNL staff and COE vendor staff collaboratively.

  16. Geriatric Core Competencies for Family Medicine Curriculum and Enhanced Skills: Care of Elderly

    PubMed Central

    Charles, Lesley; Triscott, Jean A.C.; Dobbs, Bonnie M.; McKay, Rhianne

    2014-01-01

    Background There is a growing mandate for Family Medicine residency programs to directly assess residents’ clinical competence in Care of the Elderly (COE). The objectives of this paper are to describe the development and implementation of incremental core competencies for Postgraduate Year (PGY)-I Integrated Geriatrics Family Medicine, PGY-II Geriatrics Rotation Family Medicine, and PGY-III Enhanced Skills COE for COE Diploma residents at a Canadian University. Methods Iterative expert panel process for the development of the core competencies, with a pre-defined process for implementation of the core competencies. Results Eighty-five core competencies were selected overall by the Working Group, with 57 core competencies selected for the PGY-I/II Family Medicine residents and an additional 28 selected for the PGY-III COE residents. The core competencies follow the CanMEDS Family Medicine roles. Both sets of core competencies are based on consensus. Conclusions Due to demographic changes, it is essential that Family Physicians have the required skills and knowledge to care for the frail elderly. The core competencies described were developed for PGY-I/II Family Medicine residents and PGY-III Enhanced Skills COE, with a focus on the development of geriatric expertise for those patients that would most benefit. PMID:24883163

  17. North American International Society for Microbial Electrochemical Technologies Meeting (Abstracts)

    DTIC Science & Technology

    2016-04-18

    systems. Unlike the well-studied case of dissolved oxygen (D.O.) effects on the facultative metabolic shift between aerobic respiration and nitrate...The Pt catalyst can effectively catalyze oxygen reduction and ensure a healthy operation of bioelectrochemical systems but its high cost limits the... effect of COEs on other species in bioelectrochemical systems. Effects of additional electron acceptors in bio-anodic processes: oxygen and sulfate

  18. Protective effect of Calendula officinalis Linn. flowers against 3-nitropropionic acid induced experimental Huntington's disease in rats.

    PubMed

    Shivasharan, B D; Nagakannan, Pandian; Thippeswamy, Boreddy Shivanandappa; Veerapur, Veeresh Prabakar; Bansal, Punit; Unnikrishnan, Mazhuvancherry K

    2013-10-01

    Oxidative stress (OS) and nitric oxide mechanisms have been recently proposed in 3-nitropropionic acid (3-NP)-induced neurotoxicity. The compounds, having antioxidant, anti-inflammatory and estrogenic effects, have been suggested for neuroprotection in different experimental models. Calendula officinalis Linn. flower extract (COE) is known for its potent antioxidant, anti-inflammatory, estrogenic and neuroprotective activities. Hence, the present study was designed to evaluate the neuroprotective effect of COE on 3-NP-induced neurotoxicity in rats by observing behavioral changes, OS and striatal damage in rat brain. Adult female Wistar rats were pretreated with vehicle or COE (100 and 200 mg/kg) for 7 days, followed by cotreatment with 3-NP (15 mg/kg, intraperitoneally) for the next 7 days. At the end of the treatment schedule, rats were evaluated for alterations in sensory motor functions and short-term memory. Animals were sacrificed and brain homogenates were used for the estimation of lipid peroxidation (LPO), glutathione, total thiols, glutathione S-transferase, catalase and nitrite. A set of brain slices was used for the evaluation of neuronal damage in the striatal region of the brain. 3-NP caused significant alterations in animal behavior, oxidative defense system evidenced by raised levels of LPO and nitrite concentration, and depletion of antioxidant levels. It also produced a loss of neuronal cells in the striatal region. Treatment with COE significantly attenuated behavioral alterations, oxidative damage and striatal neuronal loss in 3-NP-treated animals. The present study shows that COE is protective against 3-NP-induced neurotoxicity in rats. The antioxidant, anti-inflammatory and estrogenic properties of COE may be responsible for its neuroprotective action.

  19. Questioning the accuracy of greenhouse gas accounting from agricultural waste: a case study.

    PubMed

    Chung, Matthew L; Shilton, Andrew N; Guieysse, Benoit; Pratt, Chris

    2013-01-01

    The New Zealand Greenhouse Gas Inventory (the NZ Inventory) uses country-specific data to quantify CH emissions from anaerobic ponds treating dairy farm effluent (315 Gg CO equivalent [CO-e] in 2009). In this study, we used literature data to: (i) evaluate the accuracy of the NZ Inventory's parameters used to quantify these CH emissions; and (ii) determine whether the NZ Inventory's scope is capturing the full spectrum of sources with bio-CH potential entering anaerobic ponds. The research indicated that the current NZ Inventory methodology is underestimating CH emissions from anaerobic ponds across New Zealand by 264 to 603 Gg CO-e annually. Moreover, the NZ Inventory is currently not accounting for (i) manure from supplementary feed pads and stand-off pads (annual CH emissions = 207-330 Gg CO-e); (ii) waste milk (153-280 Gg CO-e); and (iii) supplementary feed waste (90-216 Gg CO-e). Annual CH emissions from anaerobic ponds on dairy farms across New Zealand are thus more likely to be 1029 to 1744 Gg CO-e, indicating that the NZ Inventory is reporting as little as 18% of actual CH emissions produced by this sector. These additional wastes are not accounted for in the methodology prescribed by the Intergovernmental Panel on Climate Change for estimating CH emissions from dairy manure. Consequently, other significant dairying nations will also probably be underestimating their waste CH emissions. Our research highlights that, if governments attempt to include country-specific emission factors in their greenhouse gas inventories, these factors must be based on an assessment of the full spectrum of sources contributing to greenhouse gas emissions within any given sector. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  20. U.S. Corps of Engineers (COE) Letters to California, Texas and Illinois Regarding Munitions on Closed Military Ranges

    EPA Pesticide Factsheets

    This memorandum responds to three letters sent by the U.S. Army Corps of Engineers (COE) representatives to the States of Texas, California, and Illinois involving interpretations of the Military Munitions Rule and state authority.

  1. Care of the elderly program at the University of Alberta

    PubMed Central

    Charles, Lesley; Dobbs, Bonnie; Triscott, Jean; McKay, Rhianne

    2014-01-01

    Abstract Problem addressed The population is aging rapidly and there are implications for health care delivery in the face of few physicians specializing in care of the elderly (COE). Objective of program To train physicians wishing to provide COE services. Program description The COE program at the University of Alberta in Edmonton is an enhanced skills diploma program lasting 6 months to 1 year, with core program requirements including geriatric inpatient care, geriatric psychiatry, ambulatory care, continuing care, and outreach. There is a longitudinal clinic component and a research project requirement. The program is designed to cover the 85 core competencies in the CanMEDS– Family Medicine roles. Conclusion There is a need for COE physicians to provide clinical care as well as fill educational, administrative, and research roles to meet the health care needs of medically complex seniors. These physicians require alternative funding and a departmental home within a university if they are to provide an academic service. PMID:25551143

  2. Gradient-Based Optimization of Wind Farms with Different Turbine Heights: Preprint

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stanley, Andrew P. J.; Thomas, Jared; Ning, Andrew

    Turbine wakes reduce power production in a wind farm. Current wind farms are generally built with turbines that are all the same height, but if wind farms included turbines with different tower heights, the cost of energy (COE) may be reduced. We used gradient-based optimization to demonstrate a method to optimize wind farms with varied hub heights. Our study includes a modified version of the FLORIS wake model that accommodates three-dimensional wakes integrated with a tower structural model. Our purpose was to design a process to minimize the COE of a wind farm through layout optimization and varying turbine hubmore » heights. Results indicate that when a farm is optimized for layout and height with two separate height groups, COE can be lowered by as much as 5%-9%, compared to a similar layout and height optimization where all the towers are the same. The COE has the best improvement in farms with high turbine density and a low wind shear exponent.« less

  3. Gradient-Based Optimization of Wind Farms with Different Turbine Heights

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Stanley, Andrew P. J.; Thomas, Jared; Ning, Andrew

    Turbine wakes reduce power production in a wind farm. Current wind farms are generally built with turbines that are all the same height, but if wind farms included turbines with different tower heights, the cost of energy (COE) may be reduced. We used gradient-based optimization to demonstrate a method to optimize wind farms with varied hub heights. Our study includes a modified version of the FLORIS wake model that accommodates three-dimensional wakes integrated with a tower structural model. Our purpose was to design a process to minimize the COE of a wind farm through layout optimization and varying turbine hubmore » heights. Results indicate that when a farm is optimized for layout and height with two separate height groups, COE can be lowered by as much as 5%-9%, compared to a similar layout and height optimization where all the towers are the same. The COE has the best improvement in farms with high turbine density and a low wind shear exponent.« less

  4. Hurricane Resilient Wind Plant Concept Study Final Report

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Dibra, Besart; Finucane, Zachary; Foley, Benjamin

    Hurricanes occur over much of the U.S. Atlantic and Gulf coasts, from Long Island to the U.S.-Mexico border, encompassing much of the nation's primary offshore wind resource. Category 5 hurricanes have made landfall as far north as North Carolina, with Category 3 hurricanes reaching New York with some frequency. Along the US West coast, typhoons strike with similar frequency and severity. At present, offshore wind turbine design practices do not fully consider the severe operating conditions imposed by hurricanes. Although universally applied to most turbine designs, International Electrotechnical Commission (IEC) standards do not sufficiently address the duration, directionality, magnitude, ormore » character of hurricanes. To assess advanced design features that could mitigate hurricane loading in various ways, this Hurricane-Resilient Wind Plant Concept Study considered a concept design study of a 500-megawatt (MW) wind power plant consisting of 10-MW wind turbines deployed in 25-meter (m) water depths in the Western Gulf of Mexico. This location was selected because hurricane frequency and severity provided a unique set of design challenges that would enable assessment of hurricane risk and projection of cost of energy (COE) changes, all in response to specific U.S. Department of Energy (DOE) objectives. Notably, the concept study pursued a holistic approach that incorporated multiple advanced system elements at the wind turbine and wind power plant levels to meet objectives for system performance and reduced COE. Principal turbine system elements included a 10-MW rotor with structurally efficient, low-solidity blades; a lightweight, permanent-magnet, direct-drive generator, and an innovative fixed substructure. At the wind power plant level, turbines were arrayed in a large-scale wind power plant in a manner aimed at balancing energy production against capital, installation, and operation and maintenance (O&M) costs to achieve significant overall reductions in COE.« less

  5. Wind turbines for electric utilities: Development status and economics

    NASA Technical Reports Server (NTRS)

    Ramler, J. R.; Donovan, R. M.

    1979-01-01

    The technology and economics of the large, horizontal-axis wind turbines currently in the Federal Wind Energy Program are presented. Wind turbine technology advancements made in the last several years are discussed. It is shown that, based on current projections of the costs of these machines when produced in quantity, they should be attractive for utility application. The cost of electricity (COE) produced at the busbar is shown to be a strong function of the mean wind speed at the installation site. The breakeven COE as a fuel saver is discussed and the COE range that would be generally attractive to utilities is indicated.

  6. Wind turbines for electric utilities - Development status and economics

    NASA Technical Reports Server (NTRS)

    Ramler, J. R.; Donovan, R. M.

    1979-01-01

    The technology and economics of the large, horizontal-axis wind turbines currently in the Federal Wind Energy Program are presented. Wind turbine technology advancements made in the last several years are discussed. It is shown that, based on current projections of the costs of these machines when produced in quantity, they should be attractive for utility application. The cost of electricity (COE) produced at the busbar is shown to be a strong function of the mean wind speed at the installation site. The breakeven COE as a 'fuel saver' is discussed and the COE range that would be generally attractive to utilities is indicated.

  7. A summary of the ECAS performance and cost results for MHD systems

    NASA Technical Reports Server (NTRS)

    Seikel, G. R.; Sovie, R. J.; Burns, R. K.; Barna, G. J.; Burkhart, J. A.; Nainiger, J. J.; Smith, J. M.

    1976-01-01

    The potential is examined of various advanced power plant concepts using coal and coal-derived fuel. The results indicate that open cycle coal fired direct preheat MHD systems have potentially one of the highest coal-pile-to-bus-bar efficiencies and also one of the lowest costs of electricity (COE) of the systems studied. Closed cycle MHD systems may have the potential to approach the efficiency and COE of open cycle MHD. The 1200-1500 F liquid metal MHD systems studied do not appear to have the potential of exceeding the efficiency or competing with the COE of advanced steam plants.

  8. 47 CFR 54.301 - Local switching support.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... requirement by summing the components listed in this paragraph. (1) Return on Investment attributable to COE... investment by the authorized interstate rate of return. Projected unseparated local switching net investment... paragraph (c) of this section: [Return on Investment attributable to COE Category 3—Included in Account 7300...

  9. 47 CFR 69.306 - Central office equipment (COE).

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... exchange carrier's signalling transfer point and the database shall be assigned to the Line Information Database subelement at § 69.120(a). All other COE Category 2 shall be assigned to the interexchange... requirement. Non-price cap local exchange carriers may use thirty percent of the interstate Local Switching...

  10. Assessing Outcomes in Optometric Education: A Commentary by the Council on Optometric Education.

    ERIC Educational Resources Information Center

    Optometric Education, 1998

    1998-01-01

    A statement of the Council for Optometric Education (COE) defines and characterizes educational outcomes, outcomes assessment, and outcomes data, and explains the reasons for outcomes assessment, its relationship to curricular design, and its function in accreditation of optometry programs. Stated COE standards and expectations of optometry…

  11. A Study of the Perceptions of Roles, Responsibilities, and Problem Areas during Facility Transition in the Military Construction Program.

    DTIC Science & Technology

    1987-09-01

    priority based on the r sul-s of the rank order analysis of the combined USAF/COE Sa a jrouo n1 or :v.e USA’ dana qrouo. The COE data group sablisn...between the Resident Engineer and the DEEC is needed. O&M Manuals. The USAF conmnents anI concerns a bo,1t -ie &M M4ani’L3 4ere: 1. Som etnes g-ttinj the...teR-2sidJent Engineer- .ini tn- Chieff oDf Contract Man age-!n-enit ( DEEC is needed. Along the same line , onie COE comnmen t statedI that thne

  12. Baker & Taylor's George Coe

    ERIC Educational Resources Information Center

    Fialkoff, Francine

    2009-01-01

    In his 30 years as a library wholesaler, first as VP and general manager of Brodart Books, Library, and School Automation divisions and since 2000 as president of the Library & Education division of Baker & Taylor (B&T), George Coe has been instrumental in a whole host of innovations. They go way beyond the selection, processing, and delivery of…

  13. A Proposed Multimedia Cone of Abstraction: Updating a Classic Instructional Design Theory

    ERIC Educational Resources Information Center

    Baukal, Charles E.; Ausburn, Floyd B.; Ausburn, Lynna J.

    2013-01-01

    Advanced multimedia techniques offer significant learning potential for students. Dale (1946, 1954, 1969) developed a Cone of Experience (CoE) which is a hierarchy of learning experiences ranging from direct participation to abstract symbolic expression. This paper updates the CoE for today's technology and learning context, specifically focused…

  14. Iridium Cyclooctene Complex That Forms a Hyperpolarization Transfer Catalyst before Converting to a Binuclear C-H Bond Activation Product Responsible for Hydrogen Isotope Exchange.

    PubMed

    Iali, Wissam; Green, Gary G R; Hart, Sam J; Whitwood, Adrian C; Duckett, Simon B

    2016-11-21

    [IrCl(COE) 2 ] 2 (1) reacts with pyridine (py) and H 2 to form crystallographically characterized IrCl(H) 2 (COE)(py) 2 (2). 2 undergoes py loss to form 16-electron IrCl(H) 2 (COE)(py) (3), with equivalent hydride ligands. When this reaction is studied with parahydrogen, 1 efficiently achieves hyperpolarization of free py (and nicotinamide, nicotine, 5-aminopyrimidine, and 3,5-lutudine) via signal amplification by reversible exchange (SABRE) and hence reflects a simple and readily available precatayst for this process. 2 reacts further over 48 h at 298 K to form crystallographically characterized (Cl)(H)(py)(μ-Cl)(μ-H)(κ-μ-NC 5 H 4 )Ir(H)(py) 2 (4). This dimer is active in the hydrogen isotope exchange process that is used in radiopharmaceutical preparations. Furthermore, while [Ir(H) 2 (COE)(py) 3 ]PF 6 (6) forms upon the addition of AgPF 6 to 2, its stability precludes its efficient involvement in SABRE.

  15. Enabling Ethical Code Embeddedness in Construction Organizations: A Review of Process Assessment Approach.

    PubMed

    Oladinrin, Olugbenga Timo; Ho, Christabel Man-Fong

    2016-08-01

    Several researchers have identified codes of ethics (CoEs) as tools that stimulate positive ethical behavior by shaping the organisational decision-making process, but few have considered the information needed for code implementation. Beyond being a legal and moral responsibility, ethical behavior needs to become an organisational priority, which requires an alignment process that integrates employee behavior with the organisation's ethical standards. This paper discusses processes for the responsible implementation of CoEs based on an extensive review of the literature. The internationally recognized European Foundation for Quality Management Excellence Model (EFQM model) is proposed as a suitable framework for assessing an organisation's ethical performance, including CoE embeddedness. The findings presented herein have both practical and research implications. They will encourage construction practitioners to shift their attention from ethical policies to possible enablers of CoE implementation and serve as a foundation for further research on ethical performance evaluation using the EFQM model. This is the first paper to discuss the model's use in the context of ethics in construction practice.

  16. Simulating the impacts of chronic ozone exposure on plant conductance and photosynthesis, and on the regional hydroclimate using WRF/Chem

    NASA Astrophysics Data System (ADS)

    Li, Jialun; Mahalov, Alex; Hyde, Peter

    2016-11-01

    The Noah-Multiparameterization land surface model in the Weather Research and Forecasting (WRF) with Chemistry (WRF/Chem) is modified to include the effects of chronic ozone exposure (COE) on plant conductance and photosynthesis (PCP) found from field experiments. Based on the modified WRF/Chem, the effects of COE on regional hydroclimate have been investigated over the continental United States. Our results indicate that the model with/without modification in its current configuration can reproduce the rainfall and temperature patterns of the observations and reanalysis data, although it underestimates rainfall in the central Great Plains and overestimates it in the eastern coast states. The experimental tests on the effects of COE include setting different thresholds of ambient ozone concentrations ([O3]) and using different linear regressions to quantify PCP against the COE. Compared with the WRF/Chem control run (i.e., without considering the effects of COE), the modified model at different experiment setups improves the simulated estimates of rainfall and temperatures in Texas and regions to the immediate north. The simulations in June, July and August of 2007-2012 show that surface [O3] decrease latent heat fluxes (LH) by 10-27 W m-2, increase surface air temperatures (T 2) by 0.6 °C-2.0 °C, decrease rainfall by 0.9-1.4 mm d-1, and decrease runoff by 0.1-0.17 mm d-1 in Texas and surrounding areas, all of which highly depends on the precise experiment setup, especially the [O3] threshold. The mechanism producing these results is that COE decreases the LH and increases sensible heat fluxes, which in turn increases the Bowen ratios and air temperatures. This lowering of the LH also results in the decrease of convective potential and finally decreases convective rainfall. Employing this modified WRF/Chem model in any high [O3] region can improve the understanding of the interactions of vegetation, meteorology, chemistry/emissions, and crop productivity.

  17. Evaluation of the interferon-γ assay on blood collected at exsanguination of cattle under field conditions for surveillance of bovine tuberculosis.

    PubMed

    Okafor, C C; Grooms, D L; Bolin, S R; Averill, J J; Kaneene, J B

    2014-12-01

    Development of point of concentration (POC) surveillance strategies for bovine tuberculosis (bTB) would facilitate global efforts to eradicate bTB. The interferon-gamma (IFNγ) assay can detect IFNγ responses to Mycobacterium bovis in blood collected at commencement of exsanguination (COE) of experimentally challenged cattle but has not been evaluated under field conditions. The current study was aimed at determining (i) whether blood collected at COE of cattle at slaughter, under field conditions, is practical to obtain and useful for identifying cattle as IFNγ positive for bTB, (ii) whether the results of the IFNγ assay obtained at COE reliably compare with results obtained from live animals in the field, and (iii) whether the identified animal(s) originated from bTB-infected or bTB-exposed herds. Cattle from three risk groups were used: the highest risk group consisted of 49 cattle from 3 bTB-infected herds; the medium risk group consisted of 24 cattle from a potentially exposed herd; and the lowest risk group consisted of 60 cattle from herds with no known history of bTB exposure. The IFNγ assay was performed on blood collected both before stunning and at COE of cattle at slaughter. An enhanced slaughter inspection for gross lesions consistent with bTB was performed on all cattle. In addition, lymph nodes were cultured for M. bovis for cattle that tested positive for bTB via the IFNγ assay and for most cattle that tested negative for bTB. Cattle, both with and without lesions consistent with bTB, were identified as positive for bTB by the IFNγ assay using blood collected at COE, but none of the positive cattle originated from the lowest risk group. The current study demonstrates that blood collected at COE of cattle is both a practical and moderately reliable sample for accessing bTB infection using the IFNγ assay. © 2013 Blackwell Verlag GmbH.

  18. A Knowledge-Base for Rehabilitation of Airfield Concrete Pavements

    DTIC Science & Technology

    1991-01-01

    pavement engineer is located at a Major Command which oversees the operation of several Air Force bases. The five largest commands are the Strategic Air... Strategic Air Command (SAC) pavement engineer at Offutt AFB, NE 1980 - 1982: COE Materials & Concrete Division (MRD) Laboratory engineer 1976 - 1980...LaFrenz TITLE OR POSITION: Strategic Air Command Pavement Engineer PHONE: MAIL ADDRESS: HQ SAC/DEM Offutt AFB, NE YEARS IN CURRENT ASSIGNMENT: 2 EXPERIENCE

  19. Student-Organized College of Education "Educational Research Exchanges" from the Student and Former Student Perspective.

    ERIC Educational Resources Information Center

    Henson, Robin K.; Guthrie, Abbie

    2001-01-01

    Discusses how some colleges of education (COEs) attempt to develop academic climate and facilitate graduate student research activity, addressing the role of student-organized internal research conferences in the transformation of student to social scientist and explicating the benefits of these internal conferences to students, faculty, and COEs.…

  20. Conceptual design of the 6 MW Mod-5A wind turbine generator

    NASA Technical Reports Server (NTRS)

    Barton, R. S.; Lucas, W. C.

    1982-01-01

    The General Electric Company, Advanced Energy Programs Department, is designing under DOE/NASA sponsorship the MOD-5A wind turbine system which must generate electricity for 3.75 cent/KWH (1980) or less. During the Conceptual Design Phase, completed in March, 1981, the MOD-5A WTG system size and features were established as a result of tradeoff and optimization studies driven by minimizing the system cost of energy (COE). This led to a 400' rotor diameter size. The MOD-5A system which resulted is defined in this paper along with the operational and environmental factors that drive various portions of the design. Development of weight and cost estimating relationships (WCER's) and their use in optimizing the MOD-5A are discussed. The results of major tradeoff studies are also presented. Subsystem COE contributions for the 100th unit are shown along with the method of computation. Detailed descriptions of the major subsystems are given, in order that the results of the various trade and optimization studies can be more readily visualized.

  1. Final Environmental Assessment: To Relocate Air Force Explosive Ordnance Disposal Administrative Complex at Eglin Air Force Base

    DTIC Science & Technology

    2006-10-01

    Trips PM10E = .0022 * Trips COE = .262 * Trips Year 2010 and beyond: VOCE = .012 * Trips NOxE = .013 * Trips PM10E = .0022 * Trips COE...Air Force Base, Florida To convert from pounds per day to tons per year: VOC (tons/yr) = VOCE * DPYII/2000 NOx (tons/yr) = NOxE * DPYII/2000

  2. Navy Explosive Ordnance Disposal School Master Development Plan for Test Area D-51 Final Environmental Assessment

    DTIC Science & Technology

    2008-01-01

    Year 2005 through 2009: VOCE = .016 * Trips NOxE = .015 * Trips PM10E = .0022 * Trips COE = .262 * Trips Year 2010 and beyond: VOCE = .012 * Trips...NOxE = .013 * Trips PM10E = .0022 * Trips COE = .262 * Trips To convert from pounds per day to tons per year: VOC (tons/yr) = VOCE * DPYII

  3. Preliminary design and economic investigations of Diffuser-Augmented Wind Turbines (DAWT). Executive summary

    NASA Astrophysics Data System (ADS)

    Foreman, K. M.

    1981-12-01

    A preferred design and configuration approach for the diffuser augmented wind turbine (DAWT) innovative wind energy conversion system is suggested. A preliminary economic assessment is made for limited production rates of units between 5 and 150 kW rated outputs. Nine point designs are used to arrive at the conclusions regarding best construction material for the diffuser and busbar cost of electricity (COE). It is estimated that for farm and cooperative end users, the COE can range between 2 and 3.5 cents pr kWh for sites with annual average wind speeds of 16 and 12 mph (25.7 and 19.3 km/h) respectively, and 150 kW rated units. No tax credits are included in these COE figures. For commercial end users of these 150 kW units, the COE ranges between 4.0 and 6.5 cents per kWh for 16 and 12 mph sites. These estimates in 1971 dollars are lower than department of energy goals set in 1978 for the rating size and end applications. Recommendations are made for future activities to maintain steady, systematic progress toward mature development of the DAWT.

  4. Tenured and Non-Tenured College of Education Faculty Motivators and Barriers in Grant Writing: A Public University in the South

    ERIC Educational Resources Information Center

    Walden, Patrick R.; Bryan, Valerie C.

    2010-01-01

    The purpose of this investigation was to identify College of Education (COE) faculty members' perceptions of motivators and barriers to grant writing at a public university in the South, to compare the university's COE faculty perceptions to previously published survey results of Colleges of Education at Research I institutions, and to compare…

  5. Roles for County Offices of Education to Support College and Career Readiness: Bridging California's Vision with Local Implementation Needs. Policy Brief

    ERIC Educational Resources Information Center

    Lewis, Jodi; Nodine, Thad; Venezia, Andrea

    2017-01-01

    This brief focuses on the potential role of County Offices of Education (COEs) in bridging the state's vision for college and career readiness with the implementation needs of local districts and schools. After summarizing the work of 10 COEs that are known for supporting districts in increasing college and career readiness, the brief raises…

  6. Final Environmental Assessment to Implement the Defense Base Closure and Realignment Commission Recommendations for Shaw Air Force Base, South Carolina

    DTIC Science & Technology

    2007-07-01

    corresponding years. Year 2005 through 2009: VOCE = .016 * Trips NOxE = .015 * Trips PM10E = .0022 * Trips COE = .262 * Trips Year 2010 and beyond: VOCE ... VOCE * DPYII/2000 Nox (tons/yr) = NOxE * DPYII/2000 PM10(tons/yr) = PM10E * DPYII/2000 CO (tons/yr) = COE * DPYII/2000 Where: Commercial

  7. Studies of breakeven prices and electricity supply potentials of nuclear fusion by a long-term world energy and environment model

    NASA Astrophysics Data System (ADS)

    Tokimatsu, K.; Asaoka, Y.; Konishi, S.; Fujino, J.; Ogawa, Y.; Okano, K.; Nishio, S.; Yoshida, T.; Hiwatari, R.; Yamaji, K.

    2002-11-01

    In response to social demand, this paper investigates the breakeven price (BP) and potential electricity supply of nuclear fusion energy in the 21st century by means of a world energy and environment model. We set the following objectives in this paper: (i) to reveal the economics of the introduction conditions of nuclear fusion; (ii) to know when tokamak-type nuclear fusion reactors are expected to be introduced cost-effectively into future energy systems; (iii) to estimate the share in 2100 of electricity produced by the presently designed reactors that could be economically selected in the year. The model can give in detail the energy and environment technologies and price-induced energy saving, and can illustrate optimal energy supply structures by minimizing the costs of total discounted energy systems at a discount rate of 5%. The following parameters of nuclear fusion were considered: cost of electricity (COE) in the nuclear fusion introduction year, annual COE reduction rates, regional introduction year, and regional nuclear fusion capacity projection. The investigations are carried out for three nuclear fusion projections one of which includes tritium breeding constraints, four future CO2 concentration constraints, and technological assumptions on fossil fuels, nuclear fission, CO2 sequestration, and anonymous innovative technologies. It is concluded that: (1) the BPs are from 65 to 125 mill kW-1 h-1 depending on the introduction year of nuclear fusion under the 550 ppmv CO2 concentration constraints; those of a business-as-usual (BAU) case are from 51 to 68 mill kW-1h-1. Uncertainties resulting from the CO2 concentration constraints and the technological options influenced the BPs by plus/minus some 10 30 mill kW-1h-1, (2) tokamak-type nuclear fusion reactors (as presently designed, with a COE range around 70 130 mill kW-1h-1) would be favourably introduced into energy systems after 2060 based on the economic criteria under the 450 and 550 ppmv CO2 concentration constraint, but not selected under the BAU case and 650 ppmv CO2 concentration constraint, and (3) the share of electricity in 2100 produced by the presently designed tokamak-type nuclear fusion reactors (introduced after 2060) is well below 30%. It should be noted that these conclusions are based upon varieties of uncertainties in scenarios and data assumptions on nuclear fusion as well as technological options.

  8. A novel oral delivery system consisting in "drug-in cyclodextrin-in nanostructured lipid carriers" for poorly water-soluble drug: vinpocetine.

    PubMed

    Lin, Congcong; Chen, Fen; Ye, Tiantian; Zhang, Lina; Zhang, Wenji; Liu, Dandan; Xiong, Wei; Yang, Xinggang; Pan, Weisan

    2014-04-25

    The purpose of this study was to develop a new delivery system based on drug cyclodextrin (CD) complexation and loading into nanostructured lipid carriers (NLC) to improve the oral bioavailability of vinpocetine (VP). Three different CDs and three different methods to obtain solid vinpocetine-cyclodextrin-tartaric acid complexes (VP-CD-TA) were contrasted. The co-evaporation vinpocetine-β-cyclodextrin-tartaric acid loaded NLC (VP-β-CD-TA COE-loaded NLC) was obtained by emulsification ultrasonic dispersion method. VP-β-CD-TA COE-loaded NLC was suitably characterized for particle size, polydispersity index, zeta potential, entrapment efficiency and the morphology. The crystallization of drug in VP-CD-TA and NLC was investigated by differential scanning calorimetry (DSC). The in vitro release study was carried out at pH 1.2, pH 6.8 and pH 7.4 medium. New Zealand rabbits were applied to investigate the pharmacokinetic behavior in vivo. The VP-β-CD-TA COE-loaded NLC presented a superior physicochemical property and selected to further study. In the in vitro release study, VP-β-CD-TA COE-loaded NLC exhibited a higher dissolution rate in the pH 6.8 and pH 7.4 medium than VP suspension and VP-NLC. The relative bioavailability of VP-β-CD-TA COE-loaded NLC was 592% compared with VP suspension and 92% higher than VP-NLC. In conclusion, the new formulation significantly improved bioavailability of VP for oral delivery, demonstrated a perspective way for oral delivery of poorly water-soluble drugs. Copyright © 2014 Elsevier B.V. All rights reserved.

  9. Immediate increase of cardiac output after percutaneous mitral valve repair (PMVR) determined by echocardiographic and invasive parameters: Patzelt: Increase of cardiac output after PMVR.

    PubMed

    Patzelt, Johannes; Zhang, Yingying; Magunia, Harry; Jorbenadze, Rezo; Droppa, Michal; Ulrich, Miriam; Cai, Shanglang; Lausberg, Henning; Walker, Tobias; Wengenmayer, Tobias; Rosenberger, Peter; Schreieck, Juergen; Seizer, Peter; Gawaz, Meinrad; Langer, Harald F

    2017-06-01

    Successful percutaneous mitral valve repair (PMVR) in patients with severe mitral regurgitation (MR) causes changes in hemodynamics. Echocardiographic calculation of cardiac output (CO) has not been evaluated in the setting of PMVR, so far. Here we evaluated hemodynamics before and after PMVR with the MitraClip system using pulmonary artery catheterization, transthoracic (TTE) and transesophageal (TEE) echocardiography. 101 patients with severe MR not eligible for conventional surgery underwent PMVR. Hemodynamic parameters were determined during and after the intervention. We evaluated changes in CO and pulmonary artery systolic pressure before and after PMVR. CO was determined with invasive parameters using the Fick method (COi) and by a combination of TTE and TEE (COe). All patients had successful clip implantation, which was associated with increased COi (from 4.6±1.4l/min to 5.4±1.6l/min, p<0.001). Furthermore, pulmonary artery systolic pressure (PASP) showed a significant decrease after PMVR (47.6±16.1 before, 44.7±15.5mmHg after, p=0.01). In accordance with invasive measurements, COe increased significantly (COe from 4.3±1.7l/min to 4.8±1.7l/min, p=0.003). Comparing both methods to calculate CO, we observed good agreement between COi and COe using Bland Altman plots. CO increased significantly after PMVR as determined by echocardiography based and invasive calculation of hemodynamics during PMVR. COe shows good agreement with COi before and after the intervention and, thus, represents a potential non-invasive method to determine CO in patients with MR not accessible by conventional surgery. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. Visualization of Flow Alternatives, Lower Missouri River

    USGS Publications Warehouse

    Jacobson, Robert B.; Heuser, Jeanne

    2002-01-01

    Background The U.S. Army Corps of Engineers (COE) 'Missouri River Master Water Control Manual' (Master Manual) review has resulted in consideration of many flow alternatives for managing the water in the river (COE, 2001; 1998a). The purpose of this report is to present flow-management alternative model results in a way that can be easily visualized and understood. This report was updated in October 2001 to focus on the specific flow-management alternatives presented by the COE in the 'Master Manual Revised Draft Environmental Impact Statement' (RDEIS; COE, 2001). The original version (February 2000) is available by clicking here. The COE, U.S. Fish and Wildlife Service (FWS), Missouri River states, and Missouri River basin tribes have been participating in discussions concerning water management of the Missouri River mainstem reservoir system (MRMRS), the Missouri River Bank Stabilization and Navigation Project, and the Kansas River reservoir system since 1986. These discussions include general input to the revision of the Master Manual as well as formal consultation under Section 7 of the Endangered Species Act. In 2000, the FWS issued a Biological Opinion that prescribed changes to reservoir management on the Missouri River that were believed to be necessary to preclude jeopardy to three endangered species, the pallid sturgeon, piping plover, and interior least tern (USFWS, 2000). The combined Missouri River system is large and complex, including many reservoirs, control structures, and free-flowing reaches extending over a broad region. The ability to assess future impacts of altered management scenarios necessarily involves complex, computational models that attempt to integrate physical, chemical, biological, and economic effects. Graphical visualization of the model output is intended to improve understanding of the differences among flow-management alternatives.

  11. An Interactive Activation Model of the Effect of Context in Perception. Part 2

    DTIC Science & Technology

    1980-07-15

    nonword strings are often seen with letters transposed if the transposition will produce legal strings (Estes, 1975a; c.f. experiment by Stevens reported...Activation Model Rumelhart & McClelland Part II 90 References Anderson, J. A. Neural models with cognitive implications. In D. LaBerge & S. J. Samuels...Washington, DC 20372 Coe391 Dr. Gory PoockNavy Personnel R&D Center Operations Research Department LT Steven D. Harris. MSC, USN San Diego, CA 92152 Code

  12. A summary of the ECAS performance and cost results for MHD system. [Energy Conversion Alternatives Study

    NASA Technical Reports Server (NTRS)

    Seikel, G. R.; Sovie, R. J.; Burns, R. K.; Barna, G. J.; Burkhart, J. A.; Nainiger, J. J.; Smith, J. M.

    1976-01-01

    The interagency-funded, NASA-coordinated Energy Conversion Alternatives Study (ECAS) has studied the potential of various advanced power plant concepts using coal and coal-derived fuel. Principle studies were conducted through prime contracts with the General Electric Company and the Westinghouse Electric Corporation. The results indicate that open-cycle coal-fired direct-preheat MHD systems have potentially one of the highest coal-pile-to-bus-bar efficiencies and also one of the lowest costs of electricity (COE) of the systems studied. Closed-cycle MHD systems may have the potential to approach the efficiency and COE of open-cycle MHD. The 1200-1500 F liquid-metal MHD systems studied do not appear to have the potential of exceeding the efficiency or competing with the COE of advanced steam plants.

  13. Preliminary design and economic investigations of Diffuser Augmented Wind Turbines (DAWT)

    NASA Astrophysics Data System (ADS)

    Foreman, K. M.

    1981-12-01

    A preferred design and configuration approach for the diffuser augmented wind turbines (DAWT) innovative wind energy conversion system is proposed. A preliminary economic assessment for limited production rates of units between 5 and 150 kw rated output was made. It is estimated that for farm and REA cooperative end users, the COE can range between 2 and 3.5 cents/kWh for sites with annual average wind speeds of 16 and 12 mph respectively and 150 kW rated units. No tax credits are included in these COE figures. For commercial end users of these 150 kW units the COE ranges between 4.0 and 6.5 cents/kWh for 16 and 12 mph sites. These estimates in 1979 dollars are lower than DOE goals set in 1978 for the rating size and end applications.

  14. Test Excavations at 3CT219 and 3CT220: Archaeological Assessment of Two Sites Along the Big Creek Channel Enlargement, Item 2, Crittenden County, Arkansas.

    DTIC Science & Technology

    1986-06-01

    Big Creek, Item 1 Memphis COE Survey & LeeDecker (1979c) (Sta 0+00-50+60) Testing 1978 Blackfish Bayou, Memphis COE Survey & LeeDecker (1979a) Items 2...the Blackfish Bayou channel enlarRement project, items 2 and 3, St. Francis and Crittenden counties, Arkansas. Iroquois Research Institute. Fairfax

  15. Marine Search, Rescue and Emergency Preparedness Study.

    DTIC Science & Technology

    1975-09-01

    Stampede, Boca, and Prosser Creek Reservoirs:) U. S. Forest Svc - Troy Kurth, Recreation Officer ,, erville District, Clair Engle and Lewiston Reservoirs: U...COE - Olin M. Taylor, Jr., Resource Mgr. IDAHO Central Snake Projects Office: B/R - Robert J. Brown, Superintendent INDIAN Carlyle Lake: COE - Wayne L...department U/W: U. S. Coast Guard HOSPITAL Tahoe Forest Hosp., Truckee 587-3541 (18 mi.) WEAVERVILLE DISTRICT, CLAIR ENGLE AND LEWISTON RESERVOIRS U.S

  16. Syllabus of Dental Materials

    DTIC Science & Technology

    1984-07-01

    Rubberloid Van R Dental Prod. Surgident Lactona Corp. Alginates Coe Alginate Coe Labs o Jeltrate L.D. Caulk Kerr Alginate Kerr/Sybron Alginate S.S. White Co...Surgident- Alginate Lactona Corp. Unijel II Unitek Corp. O Combination Agar/a ig inate Colloid 80 U.S. Shiza Corp. Dentloid Denterials, Ltd...66061 (215) 277-3800 (913) 782-2200 Shofu Dental Corp. Lactona Corp. (subsidary of 4025 Bohannon Dr. Warner-Lambert Co.) Menlo Park, CA 94025 . Academy

  17. Final Environmental Assessment: For Construction of an Addition to the Joint Strike Fighter Reprogramming Facility, Building 614, on Eglin Air Force Base, Florida

    DTIC Science & Technology

    2007-01-01

    VOCE = .016 * Trips NOxE = .015 * Trips PM10E = .0022 * Trips COE = .262 * Trips Year 2010 and beyond: VOCE = .012 * Trips NOxE = .013...Trips PM10E = .0022 * Trips COE = .262 * Trips E = emissions To convert from pounds per day to tons per year: VOC (tons/yr) = VOCE * DPYII/2000 lbs

  18. Identifying the Priority Topics for the Assessment of Competence in Care of the Elderly

    PubMed Central

    Frank, Chris C.; Allen, Tim; Lozanovska, Tatjana; Arcand, Marcel; Feldman, Sidney; Lam, Robert E.; Mehta, Pravinsagar G.; Mangal, Nadia Y.

    2018-01-01

    Background With Canada’s senior population increasing, there is greater demand for family physicians with enhanced skills in Care of the Elderly (COE). The College of Family Physicians Canada (CFPC) has introduced Certificates of Added Competence (CACs), one being in COE. Our objective is to summarize the process used to determine the Priority Topics for the assessment of competence in COE. Methods A modified Delphi technique was used, with online surveys and face-to-face meetings. The Working Group (WG) of six physicians acted as the nominal group, and a larger group of randomly selected practitioners from across Canada acted as the Validation Group (VG). The WG, and then the VG, completed electronic write-in surveys that asked them to identify the Priority Topics. Responses were compiled, coded, and tabulated to identify the topics and to calculate the frequencies of their selection. The WG used face-to-face meetings and iterative discussion to decide on the final topic names. Results The correlation between the initial Priority Topic list identified by the VG and that identified by the WG is 0.6793. The final list has 18 Priority Topics. Conclusion Defining the required competencies is a first step to establishing national standards in COE. PMID:29581816

  19. Size, Accumulation and Performance for Research Grants: Examining the Role of Size for Centres of Excellence

    PubMed Central

    Bloch, Carter; Schneider, Jesper W.; Sinkjær, Thomas

    2016-01-01

    The present paper examines the relation between size, accumulation and performance for research grants, where we examine the relation between grant size for Centres of Excellence (CoE) funded by the Danish National Research Foundation (DNRF) and various ex post research performance measures, including impact and shares of highly cited articles. We examine both the relation between size and performance and also how performance for CoEs evolves over the course of grant periods. In terms of dynamics, it appears that performance over the grant period (i.e. 10 years) is falling for the largest CoEs, while it is increasing for those among the smallest half. Overall, multivariate econometric analysis finds evidence that performance is increasing in grant size and over time. In both cases, the relation appears to be non-linear, suggesting that there is a point at which performance peaks. The CoEs have also been very successful in securing additional funding, which can be viewed as a ‘cumulative effect’ of center grants. In terms of new personnel, the far majority of additional funding is spent on early career researchers, hence, this accumulation would appear to have a ‘generational’ dimension, allowing for scientific expertise to be passed on to an increasing number of younger researchers. PMID:26862907

  20. Optimising Regionalisation Techniques: Identifying Centres of Endemism in the Extraordinarily Endemic-Rich Cape Floristic Region

    PubMed Central

    Bradshaw, Peter L.; Colville, Jonathan F.; Linder, H. Peter

    2015-01-01

    We used a very large dataset (>40% of all species) from the endemic-rich Cape Floristic Region (CFR) to explore the impact of different weighting techniques, coefficients to calculate similarity among the cells, and clustering approaches on biogeographical regionalisation. The results were used to revise the biogeographical subdivision of the CFR. We show that weighted data (down-weighting widespread species), similarity calculated using Kulczinsky’s second measure, and clustering using UPGMA resulted in the optimal classification. This maximized the number of endemic species, the number of centres recognized, and operational geographic units assigned to centres of endemism (CoEs). We developed a dendrogram branch order cut-off (BOC) method to locate the optimal cut-off points on the dendrogram to define candidate clusters. Kulczinsky’s second measure dendrograms were combined using consensus, identifying areas of conflict which could be due to biotic element overlap or transitional areas. Post-clustering GIS manipulation substantially enhanced the endemic composition and geographic size of candidate CoEs. Although there was broad spatial congruence with previous phytogeographic studies, our techniques allowed for the recovery of additional phytogeographic detail not previously described for the CFR. PMID:26147438

  1. Lake Holloman Recreational Area Development Environmental Assessment

    DTIC Science & Technology

    2009-08-01

    facilities Total daily trips are applied to the following factors depending on the corresponding years. Year 2005 through 2009: VOCE = .016...Trips NOxE = .015 * Trips PM10E = .0022 * Trips COE = .262 * Trips Year 2010 and beyond: VOCE = .012 * Trips NOxE = .013 * Trips PM10E = .0022...Trips COE = .262 * Trips To convert from pounds per day to tons per year: VOC (tons/yr) = VOCE * DPYII/2000 NOx (tons/yr) = NOxE * DPYII/2000

  2. Final Environmental Assessment for the Military Family Housing Privatization Initiative

    DTIC Science & Technology

    2006-09-01

    Year 2005 through 2009: VOCE = .016 * Trips NOxE = .015 * Trips PM10E = .0022 * Trips COE = .262 * Trips Appendix A Additional Materials Final...Environmental Assessment Page A-39 Military Family Housing Privatization Initiative Robins Air Force Base, Georgia Year 2010 and beyond: VOCE ...yr) = VOCE * DPYII/2000 NOx (tons/yr) = NOxE * DPYII/2000 PM10 (tons/yr) = PM10E * DPYII/2000 CO (tons/yr) = COE * DPYII/2000 Where: Area of

  3. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Crolley, R.; Thompson, M.

    There has been a need for a faster and cheaper deployment model for information technology (IT) solutions to address waste management needs at US Department of Energy (DOE) complex sites for years. Budget constraints, challenges in deploying new technologies, frequent travel, and increased job demands for existing employees have prevented IT organizations from staying abreast of new technologies or deploying them quickly. Despite such challenges, IT organizations have added significant value to waste management handling through better worker safety, tracking, characterization, and disposition at DOE complex sites. Systems developed for site-specific missions have broad applicability to waste management challenges andmore » in many cases have been expanded to meet other waste missions. Radio frequency identification (RFID) and global positioning satellite (GPS)-enabled solutions have reduced the risk of radiation exposure and safety risks. New web-based and mobile applications have enabled precision characterization and control of nuclear materials. These solutions have also improved operational efficiencies and shortened schedules, reduced cost, and improved regulatory compliance. Collaboration between US Department of Energy (DOE) complex sites is improving time to delivery and cost efficiencies for waste management missions with new information technologies (IT) such as wireless computing, global positioning satellite (GPS), and radio frequency identification (RFID). Integrated solutions developed at separate DOE complex sites by new technology Centers of Excellence (CoE) have increased material control and accountability, worker safety, and environmental sustainability. CoEs offer other DOE sister sites significant cost and time savings by leveraging their technology expertise in project scoping, implementation, and ongoing operations.« less

  4. Shaw Air Force Base Infrastructure Project Environmental Assessment

    DTIC Science & Technology

    2008-09-01

    are the applied to the following factors depending on the corresponding years. Year 2009: VOCE = .016 * Trips NOXE = .015 * Trips PM10E...0022 * Trips COE = .262 * Trips Year 2010 and beyond: VOCE = .012 * Trips NOXE = .013 * Trips PM10E = .0022 * Trips COE = .262 * Trips To...convert from pounds per day to tons per year: VOC (tons/yr) = VOCE * DPYII/2000 Nox (tons/yr) = NOxE * DPYII/2000 PM10(tons/yr) = PM10E

  5. Effects of coke oven emissions and benzo[a]pyrene on blood pressure and electrocardiogram in coke oven workers.

    PubMed

    Yang, Kai; Jiang, Xuejun; Cheng, Shuqun; Chen, Chengzhi; Cao, Xianqing; Tu, Baijie

    2017-01-24

    To evaluate the effects of occupational exposures to coke oven emissions (COEs) and benzo[a]pyrene (B[a]P) on the prevalence of hypertension and abnormal electrocardiogram (ECG) in coke oven workers. We included 880 coke oven workers and 710 oxygen employees in the exposed and control groups, respectively. Blood pressure (BP), ECG, blood lipid levels, and glucose levels of all subjects were measured. COE and B[a]P concentrations at the bottom, side, and top of the oven and control plants were estimated by weighing and high-performance liquid chromatography. The COE concentration at the top and side was higher than that at the bottom (P < 0.05). The levels of B[a]P at the top and side significantly exceeded the limit value. Abnormal BP, ECG, the detection ratio of hypertension and left ventricular high voltage were significantly greater in the exposed group than in the control group (P < 0.05). The logistic regression analysis results revealed that age and B[a]P exposure were risk factors for hypertension in coke oven workers (P < 0.05) and both were risk factors for abnormal ECG (P < 0.05). Moreover, B[a]P exposure, age, and gender were risk factors for impaired fasting glucose in coke oven workers (P < 0.05). B[a]P and COE exposures are risk factors for hypertension and abnormal ECG in coke oven workers.

  6. Effectiveness of a Core-Competency-based Program on Residents' Learning and Experience.

    PubMed

    Charles, Lesley; Triscott, Jean; Dobbs, Bonnie; Tian, Peter George; Babenko, Oksana

    2016-06-01

    The Care of the Elderly (COE) Diploma Program is a six-to-twelve-month enhanced skills program taken after two years of core residency training in Family Medicine. In 2010, we developed and implemented a core-competency-based COE Diploma program (CC), in lieu of one based on learning objectives (LO). This study assessed the effectiveness of the core-competency-based program on residents' learning and their training experience as compared to residents trained using learning objectives. The data from the 2007-2013 COE residents were used in the study, with nine and eight residents trained in the LO and CC programs, respectively. Residents' learning was measured using preceptors' evaluations of residents' skills/abilities throughout the program (118 evaluations in total). Residents' rating of training experience was measured using the Graduate's Questionnaire which residents completed after graduation. For residents' learning, overall, there was no significant difference between the two programs. However, when examined as a function of the four CanMEDS roles, there were significant increases in the CC residents' scores for two of the CanMEDS roles: Communicator/Collaborator/Manager and Scholar compared to residents in the LO program. With respect to residents' training experience, seven out of ten program components were rated by the CC residents higher than by the LO residents. The implementation of a COE CC program appears to facilitate resident learning and training experience.

  7. Association between plasma BPDE‐Alb adduct concentrations and DNA damage of peripheral blood lymphocytes among coke oven workers

    PubMed Central

    Wang, Hong; Chen, Weihong; Zheng, Hongyan; Guo, Liang; Liang, Huashan; Yang, Xiaobo; Bai, Yun; Sun, Jianya; Su, Yougong; Chen, Yongwen; Yuan, Jing; Bi, Yongyi; Wei, Qingyi; Wu, Tangchun

    2007-01-01

    Objectives Coke oven emissions (COE) containing polycyclic aromatic hydrocarbons (PAHs) can induce both benzo[a]pyrene‐r‐7, t‐8, t‐9,c‐10‐tetrahydotetrol‐albumin (BPDE‐Alb) adducts and DNA damage. However, the relation between these biomarkers for early biological effects is not well documented in coke oven workers. Methods In this study, the authors recruited 207 male workers exposed to COE and 102 controls not exposed to COE in the same steel plant in northern China. They measured BPDE‐Alb adduct concentrations in plasma with reverse‐phase high performance liquid chromatography and DNA damage in peripheral blood lymphocytes with alkaline comet assay. Results The results showed that the median concentration of BPDE‐Alb adducts in the exposed group (34.36 fmol/mg albumin) was significantly higher than that in the control group (21.90 fmol/mg albumin, p = 0.012). The mean Olive tail moment (Olive TM) of DNA damage in the exposed and control groups were 1.20 and 0.63, respectively (p = 0.000). Multivariate logistic regression analysis revealed that the odds ratio (OR) for BPDE‐Alb adduct and Olive TM associated with the exposure were 1.72 (95% CI 1.06 to 2.81) and 1.96 (95% CI 1.20 to 3.19), respectively. These results show significant correlations between the concentrations of BPDE‐Alb adduct and Olive TM levels in exposed group (r = 0.235, p = 0.001) but not in control group (r = 0.093, p = 0.353). Conclusion The results suggest that occupational exposure to COE may induce both BPDE–Alb adducts and DNA damage in the lymphocytes of coke oven workers and that these two markers are useful for monitoring exposure to COE in the workplace. PMID:17449561

  8. Final Environmental Assessment for the Military Family Housing Privatization Initiative Columbus Air Force Base, Mississippi

    DTIC Science & Technology

    2005-05-03

    daily trips are applied to the following factors depending on the corresponding years. Year 2005 through 2009: VOCE = .016 * Trips NOxE = .015...Trips PM10E = .0022 * Trips COE = .262 * Trips Year 2010 and beyond: VOCE = .012 * Trips NOxE = .013 * Trips PM10E = .0022 * Trips COE...262 * Trips To convert from pounds per day to tons per year: VOC (tons/yr) = VOCE * DPYII/2000 NOx (tons/yr) = NOxE * DPYII/2000 PM10 (tons/yr

  9. Environmental Assessment for the Construction of a Three-Bay Multi-Aircraft Hangar Tinker Air Force Base, Oklahoma

    DTIC Science & Technology

    2008-01-01

    Years 2005 through 2009: VOCE = .016 * Trips NOxE = .015 * Trips PM10E = .0022 * Trips COE = .262 * Trips Appendix A: Air Quality January 2008...Final EA for the Construction of a Three-Bay Multi-Aircraft Hangar Page A-9 Tinker Air Force Base, Oklahoma Years 2010 and beyond: VOCE = .012...Trips NOxE = .013 * Trips PM10E = .0022 * Trips COE = .262 * Trips To convert from pounds per day to tons per year: VOC (tons/year) = VOCE

  10. Final Environmental Assessment for the Okaloosa Regional Airport Expansion at Eglin Air Force Base, FL

    DTIC Science & Technology

    2006-06-01

    construction Total daily trips are then applied to the following factors depending on the corresponding years. Year 2005 through 2009: VOCE ...016 * Trips NOxE = .015 * Trips PM10E = .0022 * Trips COE = .262 * Trips Year 2010 and beyond: VOCE = .012 * Trips NOxE = .013 * Trips PM10E...0022 * Trips COE = .262 * Trips To convert from pounds per day to tons per year: VOC (tons/yr) = VOCE * DPYII/2000 Nox (tons/yr) = NOxE

  11. PREFACE: The Third 21COE Symposium: Astrophysics as Interdisciplinary Science

    NASA Astrophysics Data System (ADS)

    Maeda, Kei-ichi; Yamada, Shoichi; Daishido, Tsuneaki

    2006-03-01

    In the last decade, we have seen a remarkable progress in observations by air-borne and satellite-loaded detectors as well as large ground-based telescopes. Cosmological parameters have been precisely determined. For example, the age of the Universe is about 14 Gyrs and the curvature of our 3-space is almost zero. We have also recognized that most of the matter content of the Universe is unknown, the mystery of Dark Energy and Dark Matter. When we look at compact objects in the Universe, recent observations of supernovae and gamma ray bursts (up to cosmological distances) have revealed a variety of high energy astrophysical phenomena much beyond our expectations. Also found are quite exotic astrophysical objects such as magnetars and probably quark stars. Now we have a lot of new observational data. The present theoretical understanding, on the other hand, is far behind such observational advances. We may need new ideas to solve such problems. In the late 20th century, astrophysicists have learned much from particle physics and nuclear physics, resulting in the deeper understanding of how the big bang universe expands and stars evolve. Then we would like to extend this practice in different directions. This volume contains lectures and contributed papers presented at ``The Third 21COE Symposium: Astrophysics as Interdisciplinary Science'', which was held at Waseda University, Tokyo, Japan, on September 1 3, 2005. The aim of the symposium is to obtain new insights into the important themes mentioned above by bringing together the latest ideas from various fields. In the symposium, we have discussed not only such mysterious and important astrophysical or cosmological objects but also some subjects closely related with other fields such as nonlinear dynamics, statistical physics and condensed matter physics. Hence the main topics in the symposium have included formations of large-scale structures, galaxies, stellar clusters as well as the nature of condensed matter in high energy compact objects, and that of dark matter and dark energy of the universe. This is in accord with the purpose of The 21st century COE program, "Holistic Research and Education Center for Physics of Self-organization Systems". We hope that the symposium and the discussions therein will be the first step for the productive collaborations in the 21st century. The symposium was sponsored by the Waseda University Grant for International Conference Operation and the 21st century COE program of Waseda University, "the Holistic Research and Education Center for Physics of Self-organization Systems". Tokyo, January, 2006

  12. Effects of coke oven emissions and benzo[a]pyrene on blood pressure and electrocardiogram in coke oven workers

    PubMed Central

    Yang, Kai; Jiang, Xuejun; Cheng, Shuqun; Chen, Chengzhi; Cao, Xianqing; Tu, Baijie

    2016-01-01

    Objective: To evaluate the effects of occupational exposures to coke oven emissions (COEs) and benzo[a]pyrene (B[a]P) on the prevalence of hypertension and abnormal electrocardiogram (ECG) in coke oven workers. Methods: We included 880 coke oven workers and 710 oxygen employees in the exposed and control groups, respectively. Blood pressure (BP), ECG, blood lipid levels, and glucose levels of all subjects were measured. COE and B[a]P concentrations at the bottom, side, and top of the oven and control plants were estimated by weighing and high-performance liquid chromatography. Results: The COE concentration at the top and side was higher than that at the bottom (P < 0.05). The levels of B[a]P at the top and side significantly exceeded the limit value. Abnormal BP, ECG, the detection ratio of hypertension and left ventricular high voltage were significantly greater in the exposed group than in the control group (P < 0.05). The logistic regression analysis results revealed that age and B[a]P exposure were risk factors for hypertension in coke oven workers (P < 0.05) and both were risk factors for abnormal ECG (P < 0.05). Moreover, B[a]P exposure, age, and gender were risk factors for impaired fasting glucose in coke oven workers (P < 0.05). Conclusions: B[a]P and COE exposures are risk factors for hypertension and abnormal ECG in coke oven workers. PMID:27885241

  13. Drug-in-cyclodextrin-in-liposomes: A novel drug delivery system for flurbiprofen.

    PubMed

    Zhang, Lina; Zhang, Qi; Wang, Xin; Zhang, Wenji; Lin, Congcong; Chen, Fen; Yang, Xinggang; Pan, Weisan

    2015-08-15

    A novel delivery system based on drug-cyclodextrin (CD) complexation and liposomes has been developed to improve therapeutic effect. Three different means, i.e., co-evaporation (COE), co-ground (GR) and co-lyophilization (COL) and three different CDs (β-CD, HP-β-CD and SBE-β-CD) were contrasted to investigate the characteristics of the end products. FP/FP-CD loaded liposomes were obtained by thin layer evaporation technique. Size, zeta potential and encapsulation efficiency were investigated by light scattering analysis and minicolumn centrifugation. Differential scanning calorimetry (DSC) and transmission electron microscopy (TEM) showed the amorphous form of complexes and spherical morphology of FP-HP-β-CD COE loaded liposomes. The pH 7.4 phosphate buffer solution (PBS) was selected as the medium for the in vitro release. Wistar rats were put into use to study the pharmacokinetic behavior in vivo. FP-HP-β-CD COE loaded liposomes showed the better physicochemical characters that followed the average particle size, polydispersity index, zeta potential and mean encapsulation efficiency 158±10 nm, 0.19±0.1, -12.4±0.1 mW and 56.1±0.5%, separately. The relative bioavailability of FP-HP-β-CD COE loaded liposomes was 420%, 201% and 402% compared with FP solution, FP-HP-β-CD and FP-liposomes, respectively. In conclusion, the novel delivery system improved the relative bioavailability of FP significantly and provided a perspective way for delivery of insoluble drugs. Copyright © 2015 Elsevier B.V. All rights reserved.

  14. Effectiveness of a Core-Competency–based Program on Residents’ Learning and Experience

    PubMed Central

    Charles, Lesley; Triscott, Jean; Dobbs, Bonnie; Tian, Peter George; Babenko, Oksana

    2016-01-01

    Background The Care of the Elderly (COE) Diploma Program is a six-to-twelve-month enhanced skills program taken after two years of core residency training in Family Medicine. In 2010, we developed and implemented a core-competency–based COE Diploma program (CC), in lieu of one based on learning objectives (LO). This study assessed the effectiveness of the core-competency–based program on residents’ learning and their training experience as compared to residents trained using learning objectives. Methods The data from the 2007–2013 COE residents were used in the study, with nine and eight residents trained in the LO and CC programs, respectively. Residents’ learning was measured using preceptors’ evaluations of residents’ skills/abilities throughout the program (118 evaluations in total). Residents’ rating of training experience was measured using the Graduate’s Questionnaire which residents completed after graduation. Results For residents’ learning, overall, there was no significant difference between the two programs. However, when examined as a function of the four CanMEDS roles, there were significant increases in the CC residents’ scores for two of the CanMEDS roles: Communicator/Collaborator/Manager and Scholar compared to residents in the LO program. With respect to residents’ training experience, seven out of ten program components were rated by the CC residents higher than by the LO residents. Conclusion The implementation of a COE CC program appears to facilitate resident learning and training experience. PMID:27403213

  15. Techno Economical Study of PV-Diesel Power System for a Remote Island in Indonesia : A Case Study of Miangas Island

    NASA Astrophysics Data System (ADS)

    Rumbayan, M.; Nagasaka, K.

    2018-05-01

    The purpose of this study is to conduct the techno economical study of PC-Diesel power system based on renewable energy available locally in a remote island. This research is a case study for Miangas island which is the border island between Indonesia and Philipines. It is located in Talaud Island regency of North Sulawesi province of Indonesia. The monthly average daily radiation in Miangas island is 5.52 kWh/m2.The research methods used are data collection and data analysis using software HOMER. Based on the simulation result, the techno economic study of PV-Diesel power plant system based on energy demand in Miangas island can be obtained. The Cost of Energy (COE), Net Present Cost (NPC) and operating cost for proposed hybrid PV-Diesel power generation can be assessed for the design power systems uses Canadian solar Max Power C56x-325P of 150 KW PV, 18 string of Surette 6CS25P, Diesel Generator 50 kW and converter Magnum MS4448PAE 25 kW. The annual electricity production from the PV Diesel system for Miangas island is 309.589 kWh in which 80.7% electricity comes from PV, 19.3% electricity comes from diesel with the 109.063 kWh excess electricity. The cost of generating electrical energy in the term of cost of energy (COE), Net Present Cost (NPC) and operating cost are 0.318 US/kWh, 719.673 US and 36.857 US respectively.

  16. Chemical contamination in aquatic ecosystems.

    PubMed

    Iwata, Hisato; Kim, Eun-Young; Yamauchi, Masanobu; Inoue, Suguru; Agusa, Tetsuro; Tanabe, Shinsuke

    2007-03-01

    The 21st Century's Center of Excellence (COE) Program "Coastal Marine Environmental Research" in Ehime University, funded by the Ministry of Education, Culture, Sports, Science and Technology, Government of Japan, started its activities in October 2002. One of the core projects of the COE Program in Ehime University is "studies on environmental behavior of hazardous chemicals and their toxic effects on wildlife". This core project deals with studies of the local and global distribution of environmental contaminants in aquatic ecosystems, retrospective analysis of such chemicals, their toxicokinetics in humans and wildlife, molecular mechanisms to determine species-specific reactions, and sensitivity of chemically induced effects, and with the development of methodology for risk assessment for the conservation of ecological and species diversity. This presentation describes our recent achievements of this project, including research on contamination by arsenic and organohalogen pollutants in the Mekong River basin and molecular mechanisms of morphologic deformities in dioxin-exposed red seabream (Pagrus major) embryos. We established the Environmental Specimen Bank (es-BANK) in Ehime University in 2004, archiving approximately 100000 cryogenic samples containing tissues of wildlife and humans that have been collected for the past 40 years. The CMES homepage offers details of samples through online database retrieval. The es-BANK facility was in operation by the end of 2005.

  17. Investigations of the Origin of the Magnetic Remanence in Late Pleistocene Lacustrine Sediments in the Mono Basin, CA

    NASA Astrophysics Data System (ADS)

    Vasquez, N.; Corley, A. D.

    2015-12-01

    In the Mono Basin, CA, fine sand, silt, and volcanic ash deposited in Pleistocene Lake Russell is exposed on the margin of Mono Lake, and on Paoha Island in the lake. The silt records the Mono Lake Excursion (MLE: Denham and Cox, 1971) and several tens of thousands of years of paleomagnetic secular variation (PSV: Denham and Cox, 1971; Liddicoat, 1976; Lund et al., 1988). The sediment is believed to be an accurate recorder of PSV because the MLE has the same signal at widely separated localities in the basin (Denham, 1974; Liddicoat and Coe, 1979; Liddicoat, 1992) with the exception at wave-cut cliffs on the southeast side of the lake (Coe and Liddicoat, 1994). Magnetite, titanomagnetite, and titanomaghemite are present in the sediment (Denham and Cox, 1971; Liddicoat, 1976; Liddicoat and Coe, 1979), which is glacial flour from the adjacent Sierra Nevada (Lajoie, 1968). X-rays of the sediment and lineation measurements show patterns of normal bedding with layers aligned such that the minimum axes are within 5-10 degrees of normal bedding, with 10 percent foliation and 1 percent lineation (Coe and Liddicoat, 1994). We explore reasons for the difference in part of the PSV record at the wave-cut cliffs beyond the interpretation of Coe and Liddicoat (1994) that paleomagnetic field strength is a controlling factor. Possibilities include the sedimentation rate - at localities on the margin of Mono Lake the rate is about 60 percent less than at the wave-cut cliffs - and lithology of the sediment. At Mill Creek on the northwest side of Mono Lake, the non-magnetic sediment fraction is coarser-grained than at the wave-cut cliffs by a factor of about two, and there is a similar difference in the total inorganic carbon (TIC) percentage by weight for the two localities. (Spokowski et al., 2011) Studies of the sediment at two localities in the basin where the Hilina Pali Excursion (Teanby et al., 2002) might be recorded (Wilson Creek and South Shore Cliffs; Liddicoat and Coe, 2013) and at an extension of the PSV record of Lund et al. (1988) show a similar pattern to the grain size distribution and TIC percentage described above. Additional measurements of the TIC in the sediments from both sides of Mono Lake for the intervals recording the possible HPE and PSV extension of Lund et al. (1988) are in progress and will be presented.

  18. Final Environmental Assessment for Construction of a Precision Measurement Equipment Laboratory Facility on Eglin Air Force Base, FL

    DTIC Science & Technology

    2006-10-01

    daily trips are then applied to the following factors depending on the corresponding years. Year 2005 through 2009: VOCE = .016 * Trips NOxE...015 * Trips PM10E = .0022 * Trips COE = .262 * Trips Year 2010 and beyond: VOCE = .012 * Trips NOxE = .013 * Trips PM10E = .0022 * Trips COE...262 * Trips E = emissions To convert from pounds per day to tons per year: VOC (tons/yr) = VOCE * DPYII/2000 lbs/ton NOx (tons/yr) = NOxE * DPYII

  19. Low-Energy Solvents For Carbon Dioxide Capture Enabled By A Combination Of Enzymes And Vacuum Regeneration

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Salmon, Sonja; House, Alan; Liu, Kun

    An integrated bench-scale system combining the attributes of the bio-renewable enzyme carbonic anhydrase (CA) with low-enthalpy CO2 absorption solvents and vacuum regeneration was designed, built and operated for 500 hours using simulated flue gas. The objective was to develop a CO2 capture process with improved efficiency and sustainability when compared to NETL Case 10 monoethanolamine (MEA) scrubbing technology. The use of CA accelerates inter-conversion between dissolved CO2 and bicarbonate ion to enhance CO2 absorption, and the use of low enthalpy CO2 absorption solvents makes it possible to regenerate the solvent at lower temperatures relative to the reference MEA-based solvent. Themore » vacuum regeneration-based integrated bench-scale system operated successfully for an accumulated 500 hours using aqueous 23.5 wt% K2CO3-based solvent containing 2.5 g/L enzyme to deliver an average 84% CO2 capture when operated with a 20% enzyme replenishment rate per ~7 hour steady-state run period. The total inlet gas flow was 30 standard liters per minute with 15% CO2 and 85% N2. The absorber temperature was 40°C and the stripper operated under 35 kPa pressure with an approximate 77°C stripper bottom temperature. Tests with a 30°C absorber temperature delivered >90% capture. On- and off-line operational measurements provided a full process data set, with recirculating enzyme, that allowed for enzyme replenishment and absorption/desorption kinetic parameter calculations. Dissolved enzyme replenishment and conventional process controls were demonstrated as straightforward approaches to maintain system performance. Preliminary evaluation of a novel flow-through ultrasonically enhanced regeneration system was also conducted, yet resulted in CO2 release within the range of temperature-dependent release, and further work would be needed to validate the benefits of ultrasonic enhanced stripping. A full technology assessment was completed in which four techno-economic cases for enzyme-enhanced aqueous K2CO3 solvent with vacuum stripping were considered and a corresponding set of sensitivity studies were developed. The cases were evaluated using bench-scale and laboratory-based observations, AspenPlus® process simulation and modeling, AspenTech’s CCE® Parametric Software, current vendor quotations, and project partners’ know-how of unit operations. Overall, the DOE target of 90% CO2 capture could be met using the benign enzyme-enhanced aqueous K2CO3-based alternative to NETL Case 10. The model-predicted plant COE performance, scaled to 550 MWe net output, was 9% higher than NETL Case 10 for an enzyme-activated case with minimized technical risk and highest confidence in physical system performance utilizing commercially available equipment. A COE improvement of 2.8% versus NETL Case 10 was predicted when favorable features of improved enzyme longevity and additional power output from a very low pressure (VLP) turbine were combined, wherein corresponding high capital and operational costs limited the level of COE benefit. The environmental, health and safety (EH&S) profile of the system was found to be favorable and was compliant with the Federal EH&S legislation reviewed. Further work on a larger scale test unit is recommended to reduce the level of uncertainty inherent in extrapolating findings from a bench-scale unit to a full scale PCC plant, and to further investigate several identified opportunities for improvement. Production feasibility and suitability of carbonic anhydrases for scale-up testing was confirmed both through the current project and through parallel efforts.« less

  20. Engineering innovation to reduce wind power COE

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ammerman, Curtt Nelson

    There are enough wind resources in the US to provide 10 times the electric power we currently use, however wind power only accounts for 2% of our total electricity production. One of the main limitations to wind use is cost. Wind power currently costs 5-to-8 cents per kilowatt-hour, which is more than twice the cost of electricity generated by burning coal. Our Intelligent Wind Turbine LDRD Project is applying LANL's leading-edge engineering expertise in modeling and simulation, experimental validation, and advanced sensing technologies to challenges faced in the design and operation of modern wind turbines.

  1. Some IR features of SiO4 and OH in coesite, and its amorphization and dehydration at ambient pressure

    NASA Astrophysics Data System (ADS)

    Liu, Xi; Ma, Yunlu; He, Qiang; He, Mingyue

    2017-10-01

    Coesite (Coe) with grain size in the range of 30-80 μm has been synthesized at 5 GPa and 1600 °C for 12 h by using a cubic press. Its unpolarized single-crystal absorption infrared (IR) spectra show 14 IR bands in the range of ∼1200-650 cm-1, five of which have high intensity (at ∼1161, 1109, 1063, 1028 and 994 cm-1) and are preliminarily assigned to the SiO4 asymmetric stretching (ν3). In addition, three sharp but relatively weak bands at ∼838, 814 and 796 cm-1 are tentatively attributed to the SiO4 asymmetric bending (ν4). The IR data also show six OH peaks in the range of 3700-3300 cm-1, with an estimated H2O content of ∼30(4) wt ppm. Following previous studies, we have assigned the peaks at ∼3464 (#7), 3421 (#8), 3406 (#9) and 3377 cm-1 (#10) to the Type-II hydrogarnet substitution, and the peaks at ∼3500 (#6a) and 3534 cm-1 (#6b) to the B-based defects, with the latter aroused by possible B contamination in the synthesizing experiments. Annealing experiments conducted consecutively at ∼200, 400, 600, 800, 1000 and 1200 °C, with every heating step lasting for 24 h, demonstrate that water diffuses quickly out of Coe at T as low as ∼600 °C. The material annealed at 1200 °C is completely dehydrated and amorphous. A quick response of the water content in Coe to the changes of P, T and composition is thus possible, which may be critical to the preservation of natural Coe in relevant geological processes. It further implies that water in Coe, and possibly in other nominally anhydrous minerals (NAMs), may behave distinctively different from the water located in the hydrous phases such as amphibole and mica, and potentially makes significant contribution to the subduction zone-related fluids.

  2. Novel Supercritical Carbon Dioxide Power Cycle Utilizing Pressured Oxy-combustion in Conjunction with Cryogenic Compression

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brun, Klaus; McClung, Aaron; Davis, John

    2014-03-31

    The team of Southwest Research Institute® (SwRI) and Thar Energy LLC (Thar) applied technology engineering and economic analysis to evaluate two advanced oxy-combustion power cycles, the Cryogenic Pressurized Oxy-combustion Cycle (CPOC), and the Supercritical Oxy-combustion Cycle. This assessment evaluated the performance and economic cost of the two proposed cycles with carbon capture, and included a technology gap analysis of the proposed technologies to determine the technology readiness level of the cycle and the cycle components. The results of the engineering and economic analysis and the technology gap analysis were used to identify the next steps along the technology development roadmapmore » for the selected cycle. The project objectives, as outlined in the FOA, were 90% CO{sub 2} removal at no more than a 35% increase in cost of electricity (COE) as compared to a Supercritical Pulverized Coal Plant without CO{sub 2} capture. The supercritical oxy-combustion power cycle with 99% carbon capture achieves a COE of $121/MWe. This revised COE represents a 21% reduction in cost as compared to supercritical steam with 90% carbon capture ($137/MWe). However, this represents a 49% increase in the COE over supercritical steam without carbon capture ($80.95/MWe), exceeding the 35% target. The supercritical oxy-combustion cycle with 99% carbon capture achieved a 37.9% HHV plant efficiency (39.3% LHV plant efficiency), when coupling a supercritical oxy-combustion thermal loop to an indirect supercritical CO{sub 2} (sCO{sub 2}) power block. In this configuration, the power block achieved 48% thermal efficiency for turbine inlet conditions of 650°C and 290 atm. Power block efficiencies near 60% are feasible with higher turbine inlet temperatures, however a design tradeoff to limit firing temperature to 650°C was made in order to use austenitic stainless steels for the high temperature pressure vessels and piping and to minimize the need for advanced turbomachinery features such as blade cooling. The overall technical readiness of the supercritical oxy-combustion cycle is TRL 2, Technology Concept, due to the maturity level of the supercritical oxy-combustor for solid fuels, and several critical supporting components, as identified in the Technical Gap Analysis. The supercritical oxycombustor for solid fuels operating at pressures near 100 atm is a unique component of the supercritical oxy-combustion cycle. In addition to the low TRL supercritical oxy-combustor, secondary systems were identified that would require adaptation for use with the supercritical oxycombustion cycle. These secondary systems include the high pressure pulverized coal feed, high temperature cyclone, removal of post-combustion particulates from the high pressure cyclone underflow stream, and micro-channel heat exchangers tolerant of particulate loading. Bench scale testing was utilized to measure coal combustion properties at elevated pressures in a CO{sub 2} environment. This testing included coal slurry preparation, visualization of coal injection into a high pressure fluid, and modification of existing test equipment to facilitate the combustion properties testing. Additional bench scale testing evaluated the effectiveness of a rotary atomizer for injecting a coal-water slurry into a fluid with similar densities, as opposed to the typical application where the high density fluid is injected into a low density fluid. The swirl type supercritical oxy-combustor was developed from initial concept to an advanced design stage through numerical simulation using FLUENT and Chemkin to model the flow through the combustor and provide initial assessment of the coal combustion reactions in the flow path. This effort enabled the initial combustor mechanical layout, initial pressure vessel design, and the conceptual layout of a pilot scale test loop. A pilot scale demonstration of the supercritical oxy-combustion cycle is proposed as the next step in the technology development. This demonstration would advance the supercritical oxy-combustion cycle and the supercritical oxy-combustor from a current TRL of 2, Technology Concept, to TRL 6, Pilot Scale System Demonstrated in a Relevant Environment, and enable the evaluation and continued refinement of the supercritical oxy-combustor and critical secondary systems.« less

  3. Self-association of short-chain nonionic amphiphiles in binary and ternary systems: comparison between the cleavable ethylene glycol monobutyrate and its ether counterparts.

    PubMed

    Zhu, Ying; Fournial, Anne-Gaëlle; Molinier, Valérie; Azaroual, Nathalie; Vermeersch, Gaston; Aubry, Jean-Marie

    2009-01-20

    In the context of environmental concerns for the production of surface active species, the introduction of a carbonyl function into the skeleton of ethyleneglycol-derived solvo-surfactants is a way to access cleavable compounds with presumed enhanced biodegradability. Ethylene glycol monobutyrate (C(3)COE(1)) was synthesized and compared to its ether counterparts, ethylene glycol monopropyl (C(3)E(1)) and monobutyl ethers (C(4)E(1)), to assess the effect of the insertion of a carbonyl function in the skeleton of short-chain ethoxylated amphiphilic compounds. In aqueous solutions, the ester has intermediate behavior between that of the two ethers with regard to surface tension, solubilization of Me-naphtalene in water, and self-diffusion by PGSE NMR. In ternary systems, C(3)COE(1) and C(3)E(1) have the same optimal oil (EACN = 2.8), which is much more polar than that of C(4)E(1) (EACN = 8.5). With regard to the ability to form structured systems, the behavior in water does not differ significantly for the three compounds, and the transition between nonassociating solvents and amphiphilic solvents, sometimes called solvo-surfactants, is gradual. In ternary systems, however, only C(4)E(1) and C(3)COE(1) form a third phase near the optimal formulation, which tends to show that C(3)COE(1) possesses the minimum amphiphilicity to get a structuration. Self-diffusion NMR studies of the one-phase domains do not, however, allow us to distinguish between different degrees of organization in the three systems.

  4. Genome-wide analysis of the bHLH gene family in planarians identifies factors required for adult neurogenesis and neuronal regeneration.

    PubMed

    Cowles, Martis W; Brown, David D R; Nisperos, Sean V; Stanley, Brianna N; Pearson, Bret J; Zayas, Ricardo M

    2013-12-01

    In contrast to most well-studied model organisms, planarians have a remarkable ability to completely regenerate a functional nervous system from a pluripotent stem cell population. Thus, planarians provide a powerful model to identify genes required for adult neurogenesis in vivo. We analyzed the basic helix-loop-helix (bHLH) family of transcription factors, many of which are crucial for nervous system development and have been implicated in human diseases. However, their potential roles in adult neurogenesis or central nervous system (CNS) function are not well understood. We identified 44 planarian bHLH homologs, determined their patterns of expression in the animal and assessed their functions using RNAi. We found nine bHLHs expressed in stem cells and neurons that are required for CNS regeneration. Our analyses revealed that homologs of coe, hes (hesl-3) and sim label progenitors in intact planarians, and following amputation we observed an enrichment of coe(+) and sim(+) progenitors near the wound site. RNAi knockdown of coe, hesl-3 or sim led to defects in CNS regeneration, including failure of the cephalic ganglia to properly pattern and a loss of expression of distinct neuronal subtype markers. Together, these data indicate that coe, hesl-3 and sim label neural progenitor cells, which serve to generate new neurons in uninjured or regenerating animals. Our study demonstrates that this model will be useful to investigate how stem cells interpret and respond to genetic and environmental cues in the CNS and to examine the role of bHLH transcription factors in adult tissue regeneration.

  5. Including carrier-mediated transport in oral uptake prediction of nutrients and pharmaceuticals in humans.

    PubMed

    O'Connor, Isabel A; Veltman, Karin; Huijbregts, Mark A J; Ragas, Ad M J; Russel, Frans G M; Hendriks, A Jan

    2014-11-01

    Most toxicokinetic models consider passive diffusion as the only mechanism when modeling the oral uptake of chemicals. However, the overall uptake of nutrients and xenobiotics, such as pharmaceuticals and environmental pollutants, can be increased by influx transport proteins. We incorporated carrier-mediated transport into a one-compartment toxicokinetic model originally developed for passive diffusion only. The predictions were compared with measured oral uptake efficiencies of nutrients and pharmaceuticals, i.e. the fraction of the chemical reaching systemic circulation. Including carrier-mediated uptake improved model predictions for hydrophilic nutrients (RMSE=10% vs. 56%, Coefficient of Efficiency CoE=0.5 vs. -9.6) and for pharmaceuticals (RMSE=21% vs. 28% and CoE=-0.4 vs. -1.1). However, the negative CoE for pharmaceuticals indicates that further improvements are needed. Most important in this respect is a more accurate estimation of vMAX and KM as well as the determination of the amount of expressed and functional transport proteins both in vivo and in vitro. Copyright © 2014 Elsevier B.V. All rights reserved.

  6. Address on the Occasion of the State of Hawai'i's Recognition of the Doctor of Education Program at the University of Hawai'i at Manoa by Governor Neil Abercrombie and Lieutenant Governor Shan S. Tsutsui, at the State Capitol Executive Chambers, Honolulu on November 20, 2014

    ERIC Educational Resources Information Center

    McEwan, Hunter

    2017-01-01

    This short address by Hunter McEwan provides a background to what a professional practice degree is and discusses some of the accomplishments of the very first group of graduates of the new EdD--the Doctorate in Professional Educational Practice--at the College of Education (COE) at the University of Hawai'i. The COE aimed at building a…

  7. Combined Pressure, Temperature Contrast and Surface-Enhanced Separation of Carbon Dioxide for Post-Combustion Carbon Capture

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wang, Zhen; Wong, Michael; Gupta, Mayank

    The Rice University research team developed a hybrid carbon dioxide (CO 2) absorption process combining absorber and stripper columns using a high surface area ceramic foam gas-liquid contactor for enhanced mass transfer and utilizing waste heat for regeneration. This integrated absorber/desorber arrangement will reduce space requirements, an important factor for retrofitting existing coal-fired power plants with CO 2 capture technology. Described in this report, we performed an initial analysis to estimate the technical and economic feasibility of the process. A one-dimensional (1D) CO 2 absorption column was fabricated to measure the hydrodynamic and mass transfer characteristics of the ceramic foam.more » A bench-scale prototype was constructed to implement the complete CO 2 separation process and tested to study various aspects of fluid flow in the process. A model was developed to simulate the two-dimensional (2D) fluid flow and optimize the CO 2 capture process. Test results were used to develop a final technoeconomic analysis and identify the most appropriate absorbent as well as optimum operating conditions to minimize capital and operating costs. Finally, a technoeconomic study was performed to assess the feasibility of integrating the process into a 600 megawatt electric (MWe) coal-fired power plant. With process optimization, $82/MWh of COE can be achieved using our integrated absorber/desorber CO 2 capture technology, which is very close to DOE's target that no more than a 35% increase in COE with CCS. An environmental, health, and safety (EH&S) assessment of the capture process indicated no significant concern in terms of EH&S effects or legislative compliance.« less

  8. Conceptual design study of the moderate size superconducting spherical tokamak power plant

    NASA Astrophysics Data System (ADS)

    Gi, Keii; Ono, Yasushi; Nakamura, Makoto; Someya, Youji; Utoh, Hiroyasu; Tobita, Kenji; Ono, Masayuki

    2015-06-01

    A new conceptual design of the superconducting spherical tokamak (ST) power plant was proposed as an attractive choice for tokamak fusion reactors. We reassessed a possibility of the ST as a power plant using the conservative reactor engineering constraints often used for the conventional tokamak reactor design. An extensive parameters scan which covers all ranges of feasible superconducting ST reactors was completed, and five constraints which include already achieved plasma magnetohydrodynamic (MHD) and confinement parameters in ST experiments were established for the purpose of choosing the optimum operation point. Based on comparison with the estimated future energy costs of electricity (COEs) in Japan, cost-effective ST reactors can be designed if their COEs are smaller than 120 mills kW-1 h-1 (2013). We selected the optimized design point: A = 2.0 and Rp = 5.4 m after considering the maintenance scheme and TF ripple. A self-consistent free-boundary MHD equilibrium and poloidal field coil configuration of the ST reactor were designed by modifying the neutral beam injection system and plasma profiles. The MHD stability of the equilibrium was analysed and a ramp-up scenario was considered for ensuring the new ST design. The optimized moderate-size ST power plant conceptual design realizes realistic plasma and fusion engineering parameters keeping its economic competitiveness against existing energy sources in Japan.

  9. The Dose–Response Decrease in Heart Rate Variability: Any Association with the Metabolites of Polycyclic Aromatic Hydrocarbons in Coke Oven Workers?

    PubMed Central

    Deng, Huaxin; Zhang, Wangzhen; Kuang, Dan; Deng, Qifei; Dai, Xiayun; Lin, Dafeng; Huang, Suli; Xin, Lili; He, Yunfeng; Huang, Kun; He, Meian; Guo, Huan; Zhang, Xiaomin; Wu, Tangchun

    2012-01-01

    Background Air pollution has been associated with an increased risk of cardiopulmonary mortality and decreased heart rate variability (HRV). However, it is unclear whether coke oven emissions (COEs) and polycyclic aromatic hydrocarbons (PAHs) are associated with HRV. Objectives Our goal in the present study was to investigate the association of exposure to COEs and the urinary metabolite profiles of PAHs with HRV of coke oven workers. Methods We measured benzene soluble matter, carbon monoxide, sulfur dioxide, particulate matters, and PAHs at different workplaces of a coke oven plant. We determined 10 urinary PAH metabolites and HRV indices of 1333 workers using gas chromatography–mass spectrometry and a 3-channel digital Holter monitor, respectively. Results Our results showed that there was a significant COEs-related dose-dependent decrease in HRV, and an inverse relationship between the quartiles of urinary 2-hydroxynaphthalene and five HRV indices (p trend<0.01 for all). After adjustment for potential confounders, elevation per interquartile range (IQR) (1.81 µg/mmol creatinine) of urinary 2-hydroxynaphthalene was associated with a 5.46% (95% CI, 2.50–8.32) decrease in standard deviation of NN intervals (SDNN). As workers worked more years, SDNN gradually declined in the same quartiles of 2-hydroxynaphthalene levels (p trend = 1.40×10−4), especially in workers with the highest levels of 2-hydroxynaphthalene. Conclusions Occupational exposure to COEs is associated with a dose-response decrease in HRV. In particular, increased exposure to 2-hydroxynaphthalene is associated with significantly decreased HRV. Increase of working years and exposure levels has resulted in a gradual decline of HRV. PMID:23024753

  10. The dose-response decrease in heart rate variability: any association with the metabolites of polycyclic aromatic hydrocarbons in coke oven workers?

    PubMed

    Li, Xiaohai; Feng, Yingying; Deng, Huaxin; Zhang, Wangzhen; Kuang, Dan; Deng, Qifei; Dai, Xiayun; Lin, Dafeng; Huang, Suli; Xin, Lili; He, Yunfeng; Huang, Kun; He, Meian; Guo, Huan; Zhang, Xiaomin; Wu, Tangchun

    2012-01-01

    Air pollution has been associated with an increased risk of cardiopulmonary mortality and decreased heart rate variability (HRV). However, it is unclear whether coke oven emissions (COEs) and polycyclic aromatic hydrocarbons (PAHs) are associated with HRV. Our goal in the present study was to investigate the association of exposure to COEs and the urinary metabolite profiles of PAHs with HRV of coke oven workers. We measured benzene soluble matter, carbon monoxide, sulfur dioxide, particulate matters, and PAHs at different workplaces of a coke oven plant. We determined 10 urinary PAH metabolites and HRV indices of 1333 workers using gas chromatography-mass spectrometry and a 3-channel digital Holter monitor, respectively. Our results showed that there was a significant COEs-related dose-dependent decrease in HRV, and an inverse relationship between the quartiles of urinary 2-hydroxynaphthalene and five HRV indices (p(trend)<0.01 for all). After adjustment for potential confounders, elevation per interquartile range (IQR) (1.81 µg/mmol creatinine) of urinary 2-hydroxynaphthalene was associated with a 5.46% (95% CI, 2.50-8.32) decrease in standard deviation of NN intervals (SDNN). As workers worked more years, SDNN gradually declined in the same quartiles of 2-hydroxynaphthalene levels (p(trend) = 1.40×10(-4)), especially in workers with the highest levels of 2-hydroxynaphthalene. Occupational exposure to COEs is associated with a dose-response decrease in HRV. In particular, increased exposure to 2-hydroxynaphthalene is associated with significantly decreased HRV. Increase of working years and exposure levels has resulted in a gradual decline of HRV.

  11. System study of a diode-pumped solid-state-laser driver for inertial fusion energy

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Orth, C.D.; Payne, S.A.

    The present a conceptual design of a diode-pumped solid-state-laser (DPSSL) driver for an inertial fusion energy (IFE) power plant based on the maximized cost of electricity (COE) as determined in a comprehensive systems study. This study contained extensive detail for all significant DPSSL physics and costs, plus published scaling relationships for the costs of the target chamber and the balance of plant (BOP). Our DPSSL design offers low development cost because it is modular, can be fully tested functionally at reduced scale, and is based on mature solid-state-laser technology. Most of the parameter values that we used are being verifiedmore » by experiments now in progress. Future experiments will address the few issues that remain. As a consequence, the economic and technical risk of our DPSSL driver concept is becoming rather low. Baseline performance at 1 GW{sub e} using a new gain medium [Yb{sup 3+}-doped Sr{sub 5}(PO{sub 4}){sub 3}F or Yb:S-FAP] includes a product of laser efficiency and target gain of {eta}G = 7, and a COE of 8.6 cents/kW{center_dot}h, although values of {eta}G {ge} 11 and COEs {le}6.6 cents/kW{center_dot}h are possible at double the assumed target gain of 76 at 3.7 MJ. We present a summary of our results, discuss why other more-common types of laser media do not perform as well as Yb:S-FAP, and present a simple model that shows where DPSSL development should proceed to reduce projected COEs.« less

  12. A program-management plan with critical-path definition for Combustion Augmentation with Thermionic Energy Conversion (CATEC)

    NASA Technical Reports Server (NTRS)

    Morris, J. F.; Merrill, O. S.; Reddy, H. K.

    1981-01-01

    Thermionic energy conversion (TEC) is discussed. In recent TEC-topping analyses, overall plant efficiency (OPE) and cost of electricity (COE) improved slightly with current capabilities and substantially with fully matured technologies. Enhanced credibility derives from proven hot-corrosion protection for TEC by silicon-carbide clads in fossil fuel combustion products. Combustion augmentation with TEC (CATEC) affords minimal cost and plant perturbation, but with smaller OPE and COE improvements than more conventional topping applications. Risk minimization as well as comparative simplicity and convenience, favor CATEC for early market penetration. A program-management plan is proposed. Inputs, characteristics, outputs and capabilities are discussed.

  13. A program-management plan with critical-path definition for Combustion Augmentation with Thermionic Energy Conversion (CATEC)

    NASA Astrophysics Data System (ADS)

    Morris, J. F.; Merrill, O. S.; Reddy, H. K.

    Thermionic energy conversion (TEC) is discussed. In recent TEC-topping analyses, overall plant efficiency (OPE) and cost of electricity (COE) improved slightly with current capabilities and substantially with fully matured technologies. Enhanced credibility derives from proven hot-corrosion protection for TEC by silicon-carbide clads in fossil fuel combustion products. Combustion augmentation with TEC (CATEC) affords minimal cost and plant perturbation, but with smaller OPE and COE improvements than more conventional topping applications. Risk minimization as well as comparative simplicity and convenience, favor CATEC for early market penetration. A program-management plan is proposed. Inputs, characteristics, outputs and capabilities are discussed.

  14. ECAS Phase I fuel cell results. [Energy Conservation Alternatives Study

    NASA Technical Reports Server (NTRS)

    Warshay, M.

    1978-01-01

    This paper summarizes and discusses the fuel cell system results of Phase I of the Energy Conversion Alternatives Study (ECAS). Ten advanced electric powerplant systems for central-station baseload generation using coal were studied by NASA in ECAS. Three types of low-temperature fuel cells (solid polymer electrolyte, SPE, aqueous alkaline, and phosphoric acid) and two types of high-temperature fuel cells (molten carbonate, MC, and zirconia solid electrolyte, SE) were studied. The results indicate that (1) overall efficiency increases with fuel cell temperature, and (2) scale-up in powerplant size can produce a significant reduction in cost of electricity (COE) only when it is accompanied by utilization of waste fuel cell heat through a steam bottoming cycle and/or integration with a gasifier. For low-temperature fuel cell systems, the use of hydrogen results in the highest efficiency and lowest COE. In spite of higher efficiencies, because of higher fuel cell replacement costs integrated SE systems have higher projected COEs than do integrated MC systems. Present data indicate that life can be projected to over 30,000 hr for MC fuel cells, but data are not yet sufficient for similarly projecting SE fuel cell life expectancy.

  15. Parametric study of prospective early commercial MHD power plants (PSPEC). General Electric Company, task 1: Parametric analysis

    NASA Technical Reports Server (NTRS)

    Marston, C. H.; Alyea, F. N.; Bender, D. J.; Davis, L. K.; Dellinger, T. C.; Hnat, J. G.; Komito, E. H.; Peterson, C. A.; Rogers, D. A.; Roman, A. J.

    1980-01-01

    The performance and cost of moderate technology coal-fired open cycle MHD/steam power plant designs which can be expected to require a shorter development time and have a lower development cost than previously considered mature OCMHD/steam plants were determined. Three base cases were considered: an indirectly-fired high temperature air heater (HTAH) subsystem delivering air at 2700 F, fired by a state of the art atmospheric pressure gasifier, and the HTAH subsystem was deleted and oxygen enrichment was used to obtain requisite MHD combustion temperature. Coal pile to bus bar efficiencies in ease case 1 ranged from 41.4% to 42.9%, and cost of electricity (COE) was highest of the three base cases. For base case 2 the efficiency range was 42.0% to 45.6%, and COE was lowest. For base case 3 the efficiency range was 42.9% to 44.4%, and COE was intermediate. The best parametric cases in bases cases 2 and 3 are recommended for conceptual design. Eventual choice between these approaches is dependent on further evaluation of the tradeoffs among HTAH development risk, O2 plant integration, and further refinements of comparative costs.

  16. Prospect of solar-PV/biogas/diesel generator hybrid energy system of an off-grid area in Bangladesh

    NASA Astrophysics Data System (ADS)

    Mandal, Soumya; Yasmin, Hosna; Sarker, M. R. I.; Beg, M. R. A.

    2017-12-01

    The study presents an analysis and suggests about how renewable sources of energy can be an alternative option to produce electricity in an off-grid area. A case study is done by surveying 235 households in an off-grid area. Techno-economic analysis of the hybrid energy system is employed by using Hybrid Optimization of Multiple Energy Resources (HOMER) software. Four solar-PV modules (each of 1kW), two biogas generators (each of 3kW), three diesel generators (each of 5kW), five batteries (each of 160 Ah) and 5kW converter is found to be the best configuration in terms of Cost of Energy (COE), environmental conditions and Renewable Fraction (RF). The Cost of Energy (COE), Net Present Cost (NPC), capital cost of this configuration is found BDT15.382, BDT10007224, and BDT2582433 respectively. The renewable fraction of this system is found 75% which indicates a lower emission compared with thegrid based system and stand-alone diesel system. Although the COE is higher than grid electricity, this system offers a cheaper option than using kerosene oil and solar home systems (SHSs).

  17. Aircraft Cabin Environmental Quality Sensors

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gundel, Lara; Kirchstetter, Thomas; Spears, Michael

    2010-05-06

    The Indoor Environment Department at Lawrence Berkeley National Laboratory (LBNL) teamed with seven universities to participate in a Federal Aviation Administration (FAA) Center of Excellence (COE) for research on environmental quality in aircraft. This report describes research performed at LBNL on selecting and evaluating sensors for monitoring environmental quality in aircraft cabins, as part of Project 7 of the FAA's COE for Airliner Cabin Environmental Research (ACER)1 effort. This part of Project 7 links to the ozone, pesticide, and incident projects for data collection and monitoring and is a component of a broader research effort on sensors by ACER. Resultsmore » from UCB and LBNL's concurrent research on ozone (ACER Project 1) are found in Weschler et al., 2007; Bhangar et al. 2008; Coleman et al., 2008 and Strom-Tejsen et al., 2008. LBNL's research on pesticides (ACER Project 2) in airliner cabins is described in Maddalena and McKone (2008). This report focused on the sensors needed for normal contaminants and conditions in aircraft. The results are intended to complement and coordinate with results from other ACER members who concentrated primarily on (a) sensors for chemical and biological pollutants that might be released intentionally in aircraft; (b) integration of sensor systems; and (c) optimal location of sensors within aircraft. The parameters and sensors were selected primarily to satisfy routine monitoring needs for contaminants and conditions that commonly occur in aircraft. However, such sensor systems can also be incorporated into research programs on environmental quality in aircraft cabins.« less

  18. Reassessing the Efficiency Penalty from Carbon Capture in Coal-Fired Power Plants.

    PubMed

    Supekar, Sarang D; Skerlos, Steven J

    2015-10-20

    This paper examines thermal efficiency penalties and greenhouse gas as well as other pollutant emissions associated with pulverized coal (PC) power plants equipped with postcombustion CO2 capture for carbon sequestration. We find that, depending on the source of heat used to meet the steam requirements in the capture unit, retrofitting a PC power plant that maintains its gross power output (compared to a PC power plant without a capture unit) can cause a drop in plant thermal efficiency of 11.3-22.9%-points. This estimate for efficiency penalty is significantly higher than literature values and corresponds to an increase of about 5.3-7.7 US¢/kWh in the levelized cost of electricity (COE) over the 8.4 US¢/kWh COE value for PC plants without CO2 capture. The results follow from the inclusion of mass and energy feedbacks in PC power plants with CO2 capture into previous analyses, as well as including potential quality considerations for safe and reliable transportation and sequestration of CO2. We conclude that PC power plants with CO2 capture are likely to remain less competitive than natural gas combined cycle (without CO2 capture) and on-shore wind power plants, both from a levelized and marginal COE point of view.

  19. Bench-Scale Silicone Process for Low-Cost CO{sub 2} Capture

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wood, Benjamin; Genovese, Sarah; Perry, Robert

    2013-12-31

    A bench-scale system was designed and built to test an aminosilicone-based solvent. A model was built of the bench-scale system and this model was scaled up to model the performance of a carbon capture unit, using aminosilicones, for CO{sub 2} capture and sequestration (CCS) for a pulverized coal (PC) boiler at 550 MW. System and economic analysis for the carbon capture unit demonstrates that the aminosilicone solvent has significant advantages relative to a monoethanol amine (MEA)-based system. The CCS energy penalty for MEA is 35.9% and the energy penalty for aminosilicone solvent is 30.4% using a steam temperature of 395more » °C (743 °F). If the steam temperature is lowered to 204 °C (400 °F), the energy penalty for the aminosilicone solvent is reduced to 29%. The increase in cost of electricity (COE) over the non-capture case for MEA is ~109% and increase in COE for aminosilicone solvent is ~98 to 103% depending on the solvent cost at a steam temperature of 395 °C (743 °F). If the steam temperature is lowered to 204 °C (400 °F), the increase in COE for the aminosilicone solvent is reduced to ~95-100%.« less

  20. Coke workers' exposure to volatile organic compounds in northern China: a case study in Shanxi Province.

    PubMed

    He, Qiusheng; Yan, Yulong; Zhang, Yanli; Wang, Xinming; Wang, Yuhang

    2015-06-01

    China is the largest coke producer and exporter in the world, and it has been a major concern that large populations of coke workers are exposed to the associated air pollutants such as volatile organic compounds (VOCs). This study aimed to preliminarily quantify the potential exposure to VOCs emitted from two representative coking plants and assess the potential health risks. Air samples from various stages of coking were collected from the topside of coke ovens and various plant areas and then analyzed for benzene, toluene, ethylbenzene, and xylene (BTEX). The time-weighted average (TWA) concentrations were used to quantify the coke oven emission (COE). The TWA concentrations for benzene were 705.6 and 290.4 μg m(-3) in plant A and plant B, respectively, which showed a higher exposure level than those reported in other countries. COE varied on the topside of coke ovens during charging and pushing processes, from 268.3 to 1197.7 μg m(-3) in plant A and 85.4-489.7 μg m(-3) in plant B. Our results indicate that benzene exposure from the diffusion of tar distillation also exerts significant health risks and thus should also be concerned. Charging and pushing activities accounted for nearly 70 % of benzene dose at the topside, and the benzene exposure risks to the coke oven workers in China were higher than those reported by US EPA. Compared to the reported emission sources, the weight-based ratios of average benzene to toluene, ethylbenzene, and xylene in different COE air samples showed unique characteristic profiles. Based on the B/T ratios from this work and from literatures on several major cities in northern China, it was evident that COE contributes significantly to the severe pollution of VOCs in the air of northern China. Future more rigorous studies are warranted to characterize VOC emission profiles in the stack gas of the coking processes in China.

  1. Elevated Levels of Urinary 8-Hydroxy-2′-deoxyguanosine, Lymphocytic Micronuclei, and Serum Glutathione S-Transferase in Workers Exposed to Coke Oven Emissions

    PubMed Central

    Liu, Ai-Lin; Lu, Wen-Qing; Wang, Zeng-Zhen; Chen, Wei-Hong; Lu, Wen-Hong; Yuan, Jing; Nan, Pei-Hong; Sun, Jian-Ya; Zou, Ya-Lin; Zhou, Li-Hong; Zhang, Chi; Wu, Tang-Chun

    2006-01-01

    To investigate associations among occupational exposure to coke oven emissions (COEs), oxidative stress, cytogenotoxic effects, change in the metabolizing enzyme glutathione S-transferase (GST), and internal levels of polycyclic aromatic hydrocarbons (PAHs) in coke oven workers, we recruited 47 male coke oven workers and 31 male control subjects from a coke oven plant in northern China. We measured the levels of 1-hydroxypyrene (1-OHP) and 8-hydroxy-2′-deoxyguanosine (8-OHdG) in urine, micronucleated binucleated cells (BNMNs) in peripheral blood lymphocyte, and GST in serum. Our results showed that the group exposed to COEs had significantly increased levels of 1-OHP [median 5.7; interquartile range (IQR), 1.4–12.0 μmol/mol creatinine] compared with the control group (3; 0.5–6.4 μmol/mol creatinine). In addition, the median levels (IQR) of 8-OHdG, BNMNs, and GST were markedly increased in the exposed [1.9 (1.4–15.4) μmol/mol creatinine; 6 (2–8) per thousand; 22.1 (14.9–31.2) U/L, respectively] compared with controls [1.3 (1.0–4.0) μmol/mol creatinine, 2 (0–4) per thousand; and 13.1 (9.5–16.7) U/L, respectively]. These results appeared to be modified by smoking. However, multivariate logistic regression analysis revealed that exposure to COEs had the highest odds ratio among variables analyzed and that smoking was not a significant confounder of the levels of studied biomarkers. Overall, the present findings suggest that COE exposure led to increased internal PAH burden, genetic damage, oxidative stress, and GST activity. The consequences of the changes in these biomarkers, such as risk of cancer, warrant further investigations. PMID:16675419

  2. Experimental Study of Quantum Graphs with Microwave Networks

    NASA Astrophysics Data System (ADS)

    Fu, Ziyuan; Koch, Trystan; Antonsen, Thomas; Ott, Edward; Anlage, Steven; Wave Chaos Team

    An experimental setup consisting of microwave networks is used to simulate quantum graphs. The networks are constructed from coaxial cables connected by T junctions. The networks are built for operation both at room temperature and superconducting versions that operate at cryogenic temperatures. In the experiments, a phase shifter is connected to one of the network bonds to generate an ensemble of quantum graphs by varying the phase delay. The eigenvalue spectrum is found from S-parameter measurements on one-port graphs. With the experimental data, the nearest-neighbor spacing statistics and the impedance statistics of the graphs are examined. It is also demonstrated that time-reversal invariance for microwave propagation in the graphs can be broken without increasing dissipation significantly by making nodes with circulators. Random matrix theory (RMT) successfully describes universal statistical properties of the system. We acknowledge support under contract AFOSR COE Grant FA9550-15-1-0171.

  3. INTEGRAL observations of GRO J1008-57 in outburst

    NASA Astrophysics Data System (ADS)

    Leyder, J.-C.; Ferrigno, C.; Tuerler, M.; Walter, R.

    2009-03-01

    The Be X-ray binary GRO J1008-57 is known to display regular outburts, with a period of 248 days (ATel #940; Coe et al. 2007, MNRAS 378, 1427). In the past, it has been detected by INTEGRAL at a level of 30 mCrab in October 2005 (ATel #647; in the 18-45 keV energy range), but also in June 2004 (Coe et al. 2007). Swift/BAT detected a brighter than usual flare in November 2007 (ATel #1298), with a level of 100 mCrab up to 400 mCrab (in the 15-50 keV energy range; see the Swift/BAT lightcurve).

  4. New records of ribbon worms (Nemertea) from Ceará, Northeast Brazil.

    PubMed

    Mendes, Cecili B; Matthews-Cascon, Helena; Norenburg, Jon L

    2016-01-05

    Of 45 species of nemerteans reported for the Brazilian coast, only two were recorded from Brazil's Northeast coast. Here we report seven new records for the state of Ceará, in Northeast Brazil: Tubulanus rhabdotus Côrrea, 1954, Carinomella cf. lactea Coe, 1905, Baseodiscus delineatus (Delle-Chiaje 1825), Cerebratulus cf. lineolatus Coe, 1905, Cerebratulus sp. 1, Cerebratulus sp. 2 and Lineidae sp. 1. Specimens were collected at the following beaches: Praia dos Dois Coqueiros, Praia do Pacheco, Pecém harbor, Praia da Pedra Rachada and Praia do Guajiru. T. rhabdotus is a new record for Northeast Brazil, Carinomella cf. lactea and Cerebratulus cf. lineolatus are new records for the South Atlantic Ocean and both genera are new records for Brazil.

  5. Overview of research in progress at the Center of Excellence

    NASA Technical Reports Server (NTRS)

    Wandell, Brian A.

    1993-01-01

    The Center of Excellence (COE) was created nine years ago to facilitate active collaboration between the scientists at Ames Research Center and the Stanford Psychology Department. Significant interchange of ideas and personnel continues between Stanford and participating groups at NASA-Ames; the COE serves its function well. This progress report is organized into sections divided by project. Each section contains a list of investigators, a background statement, progress report, and a proposal for work during the coming year. The projects are: Algorithms for development and calibration of visual systems, Visually optimized image compression, Evaluation of advanced piloting displays, Spectral representations of color, Perception of motion in man and machine, Automation and decision making, and Motion information used for navigation and control.

  6. The patterning center of excellence (CoE): an evolving lithographic enablement model

    NASA Astrophysics Data System (ADS)

    Montgomery, Warren; Chun, Jun Sung; Liehr, Michael; Tittnich, Michael

    2015-03-01

    As EUV lithography moves toward high-volume manufacturing (HVM), a key need for the lithography materials makers is access to EUV photons and imaging. The SEMATECH Resist Materials Development Center (RMDC) provided a solution path by enabling the Resist and Materials companies to work together (using SUNY Polytechnic Institute's Colleges of Nanoscale Science and Engineering (SUNY Poly CNSE) -based exposure systems), in a consortium fashion, in order to address the need for EUV photons. Thousands of wafers have been processed by the RMDC (leveraging the SUNY Poly CNSE/SEMATECH MET, SUNY Poly CNSE Alpha Demo Tool (ADT) and the SEMATECH Lawrence Berkeley MET) allowing many of the questions associated with EUV materials development to be answered. In this regard the activities associated with the RMDC are continuing. As the major Integrated Device Manufacturers (IDMs) have continued to purchase EUV scanners, Materials companies must now provide scanner based test data that characterizes the lithography materials they are producing. SUNY Poly CNSE and SEMATECH have partnered to evolve the RMDC into "The Patterning Center of Excellence (CoE)". The new CoE leverages the capability of the SUNY Poly CNSE-based full field ASML 3300 EUV scanner and combines that capability with EUV Microexposure (MET) systems resident in the SEMATECH RMDC to create an integrated lithography model which will allow materials companies to advance materials development in ways not previously possible.

  7. 49 CFR 399.203 - Applicability.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... STANDARDS Step, Handhold, and Deck Requirements for Commercial Motor Vehicles § 399.203 Applicability. This subpart applies to all trucks and truck-tractors, having a high profile cab-over-engine (COE...

  8. Preface

    NASA Astrophysics Data System (ADS)

    Makabe, Toshiaki; Samukawa, Seiji

    2007-06-01

    Twenty-first century will be the era of the design technology on a firm basis of physics and chemistry under circumstances of a prospective high-speed computing along the line of environmentally friendly and economically saving society. The 4th International Workshop on Basic Aspects of Nonequilibrium Plasmas Interacting with Surfaces (BANPIS); Negative ions, their function & designability, and the 4th EU-Japan Joint Symposium on Plasma Processes (JSPP) were held at Hotel Highland Resort close to Mt. Fuji in Japan on January 30 - February 1, 2006. The joint conference was organized by the 21st century Center of Excellence (COE) for ;Optical & Electronic Device Technology for Access Networks; in Keio University, and co-operated by the Center for ;Atomic and Molecular Engineering,; in Open University, and by The Japan Society of Applied Physics.

  9. Novel Solvent System for Post Combustion CO{sub 2} Capture

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Brown, Alfred; Brown, Nathan

    2013-09-30

    The purpose of this project was to evaluate the performance of ION’s lead solvent and determine if ION’s solvent candidate could potentially meet DOE’s target of achieving 90% CO{sub 2} Capture from a 550 MWe Pulverized Coal Plant without resulting in an increase in COE greater than 35%. In this project, ION’s lead solvent demonstrated a 65% reduction in regeneration energy and a simultaneous 35% reduction in liquid to gas ratio (L/G) in comparison to aqMEA at 90% CO{sub 2} capture using actual flue gas at 0.2 MWe. Results have clearly demonstrated that the ION technology is in line withmore » DOE performance expectations and has the potential to meet DOE’s performance targets in larger scale testing environments.« less

  10. Cost analysis of DAWT innovative wind energy systems

    NASA Astrophysics Data System (ADS)

    Foreman, K. M.

    The results of a diffuser augmented wind turbine (DAWT) preliminary design study of three constructional material approaches and cost analysis of DAWT electrical energy generation are presented. Costs are estimated assuming a limited production run (100 to 500 units) of factory-built subassemblies and on-site final assembly and erection within 200 miles of regional production centers. It is concluded that with the DAWT the (busbar) cost of electricity (COE) can range between 2.0 and 3.5 cents/kW-hr for farm and REA cooperative end users, for sites with annual average wind speeds of 16 and 12 mph respectively, and 150 kW rated units. No tax credit incentives are included in these figures. For commercial end users of the same units and site characteristics, the COE ranges between 4.0 and 6.5 cents/kW-hr.

  11. Combined Cycle Power Generation Employing Pressure Gain Combustion

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Holley, Adam

    The Phase I program assessed the potential benefit of applying pressure gain combustion (PGC) technology to a natural gas combined cycle power plant. A conceptual design of the PGC integrated gas turbine was generated which was simulated in a detailed system modeling tool. The PGC integrated system was 1.93% more efficient, produced 3.09% more power, and reduced COE by 0.58%. Since the PGC system used had the same fuel flow rate as the baseline system, it also reduced CO 2 emissions by 3.09%. The PGC system did produce more NOx than standard systems, but even with the performanceand cost penaltiesmore » associated with the cleanup system it is better in every measure. This technology benefits all of DOE’s stated program goals to improve plant efficiency, reduce CO 2 production, and reduce COE.« less

  12. De novo variants in EBF3 are associated with hypotonia, developmental delay, intellectual disability, and autism

    PubMed Central

    Tanaka, Akemi J.; Cho, Megan T.; Willaert, Rebecca; Retterer, Kyle; Zarate, Yuri A.; Bosanko, Katie; Stefans, Vikki; Oishi, Kimihiko; Williamson, Amy; Wilson, Golder N.; Basinger, Alice; Barbaro-Dieber, Tina; Ortega, Lucia; Sorrentino, Susanna; Gabriel, Melissa K.; Anderson, Ilse J.; Sacoto, Maria J. Guillen; Schnur, Rhonda E.; Chung, Wendy K.

    2017-01-01

    Using whole-exome sequencing, we identified seven unrelated individuals with global developmental delay, hypotonia, dysmorphic facial features, and an increased frequency of short stature, ataxia, and autism with de novo heterozygous frameshift, nonsense, splice, and missense variants in the Early B-cell Transcription Factor Family Member 3 (EBF3) gene. EBF3 is a member of the collier/olfactory-1/early B-cell factor (COE) family of proteins, which are required for central nervous system (CNS) development. COE proteins are highly evolutionarily conserved and regulate neuronal specification, migration, axon guidance, and dendritogenesis during development and are essential for maintaining neuronal identity in adult neurons. Haploinsufficiency of EBF3 may affect brain development and function, resulting in developmental delay, intellectual disability, and behavioral differences observed in individuals with a deleterious variant in EBF3. PMID:29162653

  13. Mechanical characterization of proanthocyanidin-dentin matrix interaction

    PubMed Central

    Castellan, Carina Strano; Pereira, Patricia Nobrega; Grande, Rosa Helena Miranda; Bedran-Russo, Ana Karina

    2010-01-01

    Objectives To characterize the properties of dentin matrix treated with two proanthocyanidin rich cross-linking agents and their effect on dentin bonded interfaces. Methods Sound human molars were cut into 0.5 mm thick dentin slabs, demineralized and either treated with one of two cross-linking agents (grape seed - GSE and cocoa seed - COE extracts) or left untreated. The modulus of elasticity of demineralized dentin was assessed after 10 or 60 min and the swelling ratio after 60 min treatment. Bacterial collagenase was also used to assess resistance to enzymatic degradation of samples subjected to ultimate tensile strength. The effect of GSE or COE on the resin-dentin bond strength was evaluated after 10 or 60 min of exposure time. Data were statistically analyzed at a 95% confidence interval. Results Both cross-linkers increased the elastic modulus of demineralized dentin as exposure time increased. Swelling ratio was lower for treated samples when compared to control groups. No statistically significant changes to the UTS indicate that collagenase had no effect on dentin matrix treated with either GSE or COE. Dentin-resin bonds significantly increased following treatment with GSE regardless of the application time or adhesive system used. Significance Increased mechanical properties and stability of dentin matrix can be achieved by the use of PA-rich collagen cross-linkers most likely due to the formation of a PA-collagen complex. The short term dentin-resin bonds can be improved after 10 minutes dentin treatment. PMID:20650510

  14. Development of a Microchannel High Temperature Recuperator for Fuel Cell Systems

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Lukas, Michael

    This report summarizes the progress made in development of microchannel recuperators for high temperature fuel cell/turbine hybrid systems for generation of clean power at very high efficiencies. Both Solid Oxide Fuel Cell/Turbine (SOFC/T) and Direct FuelCell/Turbine (DFC/T) systems employ an indirectly heated Turbine Generator to supplement fuel cell generated power. The concept extends the high efficiency of the fuel cell by utilizing the fuel cell’s byproduct heat in a Brayton cycle. Features of the SOFC/T and DFC/T systems include: electrical efficiencies of up to 65% on natural gas, minimal emissions, reduced carbon dioxide release to the environment, simplicity in design,more » and potential cost competitiveness with existing combined cycle power plants. Project work consisted of candidate material selection from FuelCell Energy (FCE) and Pacific Northwest National Laboratory (PNNL) institutional databases as well as from industrial and academic literature. Candidate materials were then downselected and actual samples were tested under representative environmental conditions resulting in further downselection. A microchannel thermal-mechanical model was developed to calculate overall device cost to be later used in developing a final Tier 1 material candidate list. Specifications and operating conditions were developed for both SOFC/T and DFC/T systems. This development included system conceptualization and progression to process flow diagrams (PFD’s) including all major equipment. Material and energy balances were then developed for the two types of systems which were then used for extensive sensitivity studies that used high temperature recuperator (HTR) design parameters (e.g., operating temperature) as inputs and calculated overall system parameters (e.g., system efficiency). The results of the sensitivity studies determined the final HTR design temperatures, pressure drops, and gas compositions. The results also established operating conditions and specifications for all equipment in the SOFC/T and DFC/T systems. Capital cost and Cost of Electricity (COE) sensitivity analyses have been completed for MW-scale SOFC/T and DFC/T systems. Environmental testing consisted of 1000-hour and 2000-hour dry air oxidation testing on leading candidate materials, used to rank order and, in part, develop a final Tier 1 material candidate list. A thermal-mechanical model was subsequently used to provide material and manufacturing cost estimations for microchannel HTR’s to further refine the Tier 1 candidates. A capital cost and 20-year levelized cost of electricity (COE) was developed for a MW-scale version of the SOFC/T system concept as well as for a MW-scale version of the DFC/T system concept. Test frameworks were established for subsequent long-term materials stability testing, including oxidation resistance and mechanical strength. Mechanical strength testing was then carried out by a third-party test laboratory. Technology demonstration vehicles (TDV’s) were designed and fabricated. Several iterations of TDV’s were fabricated, each improved over the previous build as far as fabrication techniques. Two of three fabricated TDV’s were integrated with the TDV Test Facility for hot-testing at simulated operating conditions. The second of these two was successfully hot-tested for over 1000 hours at simulated temperature and pressure. Post-test leakdown assessment showed negligible leakage at benchtop conditions of 30 psig, a considerable improvement over the previous TDV’s.« less

  15. 47 CFR 69.401 - Direct expenses.

    Code of Federal Regulations, 2010 CFR

    2010-10-01

    ... elements in the same proportions as the combined investment in COE, IOT, and C&WF apportioned to each... shall be deemed to be associated with § 69.303(b) IOT investment for purposes of the apportionment...

  16. 77 FR 6805 - Eligibility Criteria for the Centers of Excellence Program in Health Professions Education for...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-09

    ...: allopathic and osteopathic medicine; pharmacy; dentistry; and behavioral or mental health. Individual schools... = 1.0 percent. ``Other'' COE graduation rate eligibility threshold = 14.1 percent. DENTISTRY (Doctors...

  17. 47 CFR 69.401 - Direct expenses.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... elements in the same proportions as the combined investment in COE, IOT, and C&WF apportioned to each... shall be deemed to be associated with § 69.303(b) IOT investment for purposes of the apportionment...

  18. 47 CFR 69.401 - Direct expenses.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... elements in the same proportions as the combined investment in COE, IOT, and C&WF apportioned to each... shall be deemed to be associated with § 69.303(b) IOT investment for purposes of the apportionment...

  19. 47 CFR 69.401 - Direct expenses.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... elements in the same proportions as the combined investment in COE, IOT, and C&WF apportioned to each... shall be deemed to be associated with § 69.303(b) IOT investment for purposes of the apportionment...

  20. 47 CFR 69.401 - Direct expenses.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... elements in the same proportions as the combined investment in COE, IOT, and C&WF apportioned to each... shall be deemed to be associated with § 69.303(b) IOT investment for purposes of the apportionment...

  1. Centers of excellence: an assessment tool for cardiovascular and orthopedic programs.

    PubMed

    Ronning, P L; Meyer, J W

    1996-10-01

    As payers place more weight on contracting with hospital/health system programs that can differentiate themselves in the market as a "true" center of excellence (COE), it becomes imperative that hospitals/health systems understand the payer perspective about those programmatic attributes that can truly differentiate them from other programs. This report describes an evaluation and rating methodology for hospital/health system subspecialty programs, particularly cardiovascular and orthopedic programs, that can be used as a self-assessment tool. Using as its core a Rating Scale and Ranking Taxonomy, the evaluation and rating methodology presented here allow cardiovascular and orthopedic programs to do the following: Understand the differentiating characteristic of COE. Rate itself against detailed criteria that are being used by payers. Compare aspects of its program to premier or benchmark programs. Interpret the results to assist with strategic and operational direction. Allocate scarce resources to implement a subspecialty program that will attract payers. The Rating Scale and Ranking Taxonomy has 20 criteria for assessing cardiovascular programs and 18 criteria for orthopedic programs. The assessment process is designed to produce two important results: dialogue and action. The underpinnings of any action is a solid business plan that clarifies the program's vision, values, and mission. They are important because most programs will ultimately pursue very similar strategies and tactics; however, the most successful subspecialty programs and practices will be the ones that can execute the strategies and tactics quickly and effectively. In addition, the changes that are engendered by this targeted yet comprehensive assessment process can lead to improved clinical and functional outcomes for patients, as well as systemic improvements in the delivery of care.

  2. DOE Office of Scientific and Technical Information (OSTI.GOV)

    Johnson, Gary E.; Thom, Ronald M.; Whiting, Allan H.

    The Bonneville Power Administration (BPA), in coordination with the U. S. Army Corps of Engineers (COE) and NOAA Fisheries, originated this project (BPA Project No. 2002-076; Contract No. DE-AC06-76RL01830, Release No. 652-24). Their intent was to develop a useful habitat restoration plan for the lower Columbia River and estuary to help guide restoration efforts and fulfill Reasonable and Prudent Alternative Action 159 of the 2000 National Marine Fisheries Service Biological Opinion on operation of the Federal Columbia River Power System. This document focuses on salmon habitat, although its ecosystem-based approach necessarily affects other species as well. Salmon habitat restoration ismore » best undertaken within the context of other biota and physical processes using an ecosystem perspective. The anticipated audience for the plan includes entities responsible for, interested in, or affected by habitat restoration in the lower Columbia River and estuary. Timeframes to apply this plan extend from the immediate (2003-2004) to the near-term (2005-2006) to the long-term (2007 and beyond). We anticipate and encourage that the plan be revised as new knowledge and experience are attained. A team comprised of the Columbia River Estuary Study Taskforce (CREST), the Lower Columbia River Estuary Partnership (Estuary Partnership), and Pacific Northwest National Laboratory (PNNL) wrote this document. The BPA and the COE, as the responsible Action Agencies, provided technical oversight. The Estuary Partnership's Science Work Group, NOAA Fisheries Habitat Conservation Division, Northwest Power Planning Council (NPPC) staff, and state and tribal fisheries management agencies reviewed drafts. The Independent Scientific Advisory Board of the NPPC reviewed and commented on the 90% draft. Revisions were incorporated into the final draft document subsequently released for public review. Extensive efforts were made to ensure a sound technical and policy basis and to solicit input from all interested parties.« less

  3. Further details on the applicability of Thellier paleointensity method: The effect of magnitude of laboratory field

    NASA Astrophysics Data System (ADS)

    Morales, Juan; Goguitchaichvili, Avto; Alva-Valdivia, Luis M.; Urrutia-Fucugauchi, Jaime

    2006-06-01

    Twenty years after Tanaka and Kono's pioneering contribution (Tanaka and Kono, 1984), we give some new details on the effect of applied field strength during Thellier paleointensity experiments. Special attention is paid to the relation of magnitude of laboratory field and Coe's quality factors (Coe et al., 1978). Full thermoremanent magnetizations were imparted on natural samples containing low-Ti titanomagnetites of pseudo-single domain structure in a 40-μT magnetic field from 600 °C to room temperature. The samples were subjected to the routine Thellier procedure using a wide range of applied laboratory fields. Results indicate that values of laboratory fields may be accurately reproduced within 2% of standard error. The quality factors, however, decrease when the magnitude of 'ancient' field does not match to applied laboratory fields. To cite this article: J. Morales et al., C. R. Geoscience 338 (2006).

  4. Transport properties of cubic crystalline Ge 2Sb 2Te 5: a potential low-temperature thermoelectric material.

    DOE PAGES

    Sun, Jifeng; Mukhopadhyay, Saikat; Subedi, Alaska; ...

    2015-03-26

    Ge 2Sb 2Te 5 (GST) has been widely used as a popular phase change material. In this study, we show that it exhibits high Seebeck coe cients 200 - 300 μV/K in its cubic crystalline phase (c-GST) at remarkably high p-type doping levels of 1 10 19 - 6 10 19 cm -3 at room temperature. More importantly, at low temperature (T = 200 K), the Seebeck coe cient was found to exceed 200 μV/K for a doping range 1 10 19 - 3.5 10 19 cm -3. Given that the lattice thermal conductivity in this phase has already beenmore » measured to be extremely low ( 0.7 W/m-K at 300 K), our results suggest the possibility of using c-GST as a low-temperature thermoelectric material.« less

  5. De novo variants in EBF3 are associated with hypotonia, developmental delay, intellectual disability, and autism.

    PubMed

    Tanaka, Akemi J; Cho, Megan T; Willaert, Rebecca; Retterer, Kyle; Zarate, Yuri A; Bosanko, Katie; Stefans, Vikki; Oishi, Kimihiko; Williamson, Amy; Wilson, Golder N; Basinger, Alice; Barbaro-Dieber, Tina; Ortega, Lucia; Sorrentino, Susanna; Gabriel, Melissa K; Anderson, Ilse J; Sacoto, Maria J Guillen; Schnur, Rhonda E; Chung, Wendy K

    2017-11-01

    Using whole-exome sequencing, we identified seven unrelated individuals with global developmental delay, hypotonia, dysmorphic facial features, and an increased frequency of short stature, ataxia, and autism with de novo heterozygous frameshift, nonsense, splice, and missense variants in the Early B-cell Transcription Factor Family Member 3 ( EBF3 ) gene. EBF3 is a member of the collier/olfactory-1/early B-cell factor (COE) family of proteins, which are required for central nervous system (CNS) development. COE proteins are highly evolutionarily conserved and regulate neuronal specification, migration, axon guidance, and dendritogenesis during development and are essential for maintaining neuronal identity in adult neurons. Haploinsufficiency of EBF3 may affect brain development and function, resulting in developmental delay, intellectual disability, and behavioral differences observed in individuals with a deleterious variant in EBF3 . © 2017 Tanaka et al.; Published by Cold Spring Harbor Laboratory Press.

  6. Assessment of oral mucosal lesions with autofluorescence imaging and reflectance spectroscopy.

    PubMed

    Lalla, Yastira; Matias, Marie Anne T; Farah, Camile S

    2016-08-01

    The aim of this prospective study was to evaluate the efficacy of a new form of autofluorescence imaging and tissue reflectance spectroscopy (Identafi, DentalEZ) in examining patients with oral mucosal lesions. The authors examined 88 patients with 231 oral mucosal lesions by conventional oral examination (COE) using white-light illumination and ×2.5 magnification loupes, followed by examination using Identafi. The authors noted fluorescence visualization loss, the presence of blanching, and diffuseness of vasculature. They performed incisional biopsies to provide definitive histopathologic diagnosis. Identafi's white light produced lesion visibility and border distinctness equivalent to COE. Identafi's violet light displayed a sensitivity of 12.5% and specificity of 85.4% for detection of oral epithelial dysplasia (OED). The authors noted visible vasculature using the green-amber light in 40.9% of lesions. Identafi's intraoral white light provided detailed visualization of oral mucosal lesions comparable with examination using an extraoral white-light source with magnification. A high level of clinical experience is required to interpret the results of autofluorescence examination as the violet light displayed low sensitivity for detection of OED. The green-amber light provided additional clinical information in relation to underlying vasculature and inflammation of lesions. Examination using Identafi can provide clinicians with more clinical data than a standard COE with yellow incandescent light, but the clinical and optical findings should be interpreted as a whole and not in isolation. Clinicians should use the light features of Identafi in a sequential and differential manner. Copyright © 2016 American Dental Association. Published by Elsevier Inc. All rights reserved.

  7. Lemongrass-Incorporated Tissue Conditioner Against Candida albicans Culture

    PubMed Central

    Amornvit, Pokpong; Srithavaj, Theerathavaj

    2014-01-01

    Background: Tissue conditioner is applied popularly with dental prosthesis during wound healing process but it becomes a reservoir of oral microbiota, especially Candida species after long-term usage. Several antifungal drugs have been mixed with this material to control fungal level. In this study, lemongrass essential oil was added into COE-COMFORT tissue conditioner before being determined for anti-Candida efficacy. Materials and Methods: Lemongrass (Cymbopogon citratus) essential oil was primarily determined for antifungal activity against C. albicans American type culture collection (ATCC) 10231 and MIC (minimum inhibitory concentration) value by agar disk diffusion and broth microdilution methods, respectively. COE-COMFORT tissue conditioner was prepared as recommended by the manufacturer after a fixed volume of the oil at its MIC or higher concentrations were mixed thoroughly in its liquid part. Antifungal efficacy of the tissue conditioner with/without herb was finally analyzed. Results: Lemongrass essential oil displayed potent antifungal activity against C. albicans ATCC 10231and its MIC value was 0.06% (v/v). Dissimilarly, the tissue conditioner containing the oil at MIC level did not cease the growth of the tested fungus. Both reference and clinical isolates of C. albicans were completely inhibited after exposed to the tissue conditioner containing at least 0.25% (v/v) of the oil (approximately 4-time MIC). The tissue conditioner without herb or with nystatin was employed as negative or positive control, respectively. Conclusion: COE-COMFORT tissue conditioner supplemented with lemongrass essential oil obviously demonstrated another desirable property as in vitro anti-Candida efficacy to minimize the risk of getting Candidal infection. PMID:25177638

  8. Quantitative In Vitro Assessment of Liposome Stability and Drug Transfer Employing Asymmetrical Flow Field-Flow Fractionation (AF4).

    PubMed

    Holzschuh, Stephan; Kaeß, Kathrin; Fahr, Alfred; Decker, Christiane

    2016-04-01

    In the present study we introduce an efficient approach for a size-based separation of liposomes from plasma proteins employing AF4. We investigated vesicle stability and release behavior of the strongly lipophilic drug temoporfin from liposomes in human plasma for various incubation times at 37°C. We used the radioactive tracer cholesteryl oleyl ether (COE) or dipalmitoyl-phosphocholine (DPPC) as lipid markers and (14)C-labeled temoporfin. First, both lipid labels were examined for their suitability as liposome markers. Furthermore, the influence of plasma origin on liposome stability and drug transfer was investigated. The effect of membrane fluidity and PEGylation on vesicle stability and drug release characteristics was also analyzed. Surprisingly, we observed an enzymatic transfer of (3)H-COE to lipoproteins due to the cholesterol ester transfer protein (CETP) in human plasma in dependence on membrane rigidity and were able to inhibit this transfer by plasma preincubation with the CETP inhibitor torcetrapib. This effect was not seen when liposomes were incubated in rat plasma. DPPC labels suffered from hydrolysis effects during preparation and/or storage. Fluid liposomes were less stable in human plasma than their PEGylated analogues or a rigid formulation. In contrast, the transfer of the incorporated drug to lipoproteins was higher for the rigid formulations. The observed effects render COE-labels questionable for in vivo studies using CEPT-rich species. Here, choline labelled (14)C-DPPC was found to be the most promising alternative. Bilayer composition has a high influence on stability and drug release of a liposomal formulation in human plasma.

  9. NK4 Antagonizes Tbx1/10 to Promote Cardiac versus Pharyngeal Muscle Fate in the Ascidian Second Heart Field

    PubMed Central

    Wang, Wei; Razy-Krajka, Florian; Siu, Eric; Ketcham, Alexandra; Christiaen, Lionel

    2013-01-01

    The heart and head muscles share common developmental origins and genetic underpinnings in vertebrates, including humans. Parts of the heart and cranio-facial musculature derive from common mesodermal progenitors that express NKX2-5, ISL1, and TBX1. This ontogenetic kinship is dramatically reflected in the DiGeorge/Cardio-Velo-Facial syndrome (DGS/CVFS), where mutations of TBX1 cause malformations in the pharyngeal apparatus and cardiac outflow tract. Cardiac progenitors of the first heart field (FHF) do not require TBX1 and segregate precociously from common progenitors of the second heart field (SHF) and pharyngeal muscles. However, the cellular and molecular mechanisms that govern heart versus pharyngeal muscle specification within this lineage remain elusive. Here, we harness the simplicity of the ascidian larva to show that, following asymmetric cell division of common progenitors, NK4/NKX2-5 promotes GATAa/GATA4/5/6 expression and cardiac specification in the second heart precursors by antagonizing Tbx1/10-mediated inhibition of GATAa and activation of Collier/Olf/EBF (COE), the determinant of atrial siphon muscle (ASM) specification. Our results uncover essential regulatory connections between the conserved cardio-pharyngeal factor Tbx1/10 and muscle determinant COE, as well as a mutual antagonism between NK4 and Tbx1/10 activities upstream of GATAa and COE. The latter cross-antagonism underlies a fundamental heart versus pharyngeal muscle fate choice that occurs in a conserved lineage of cardio-pharyngeal progenitors. We propose that this basic ontogenetic motif underlies cardiac and pharyngeal muscle development and evolution in chordates. PMID:24311985

  10. 77 FR 7245 - Federal Property Suitable as Facilities To Assist the Homeless

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-02-10

    ...; COE: Mr. Scott Whiteford, Army Corps of Engineers, Real Estate, CEMP-CR, 441 G Street NW., Washington... 21005 Status: Unutilized Comments: 44,352 sq. ft., needs rehab, most recent use--chemistry lab, off-site...

  11. 75 FR 11882 - Environmental Impact Statements and Regulations; Availability of EPA Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-12

    ... Status, Implementation, United States. Summary: EPA does not object to the proposed project. Rating LO.... Rating LO. EIS No. 20100010, ERP No. D-COE-E39079-NC, Surf City and North Topsail Beach Project, To...

  12. Graduate student recruiting into critical transportation infrastructure areas of interest.

    DOT National Transportation Integrated Search

    2013-01-01

    This report presents the results of a three-year, intensive recruiting and mentoring program in : the University of Oklahomas (OU) College of Engineering (CoE). Highly qualified and diverse : graduate students were sought to pursue degrees in tran...

  13. Field guide to the Mesozoic arc and accretionary complex of South-Central Alaska, Indian to Hatcher Pass

    USGS Publications Warehouse

    Karl, Susan M.; Oswald, P.J.; Hults, Chad P.

    2015-01-01

    This field trip traverses exposures of a multi-generation Mesozoic magmatic arc and subduction-accretion complex that had a complicated history of magmatic activity and experienced variations in composition and deformational style in response to changes in the tectonic environment. This Mesozoic arc formed at an unknown latitude to the south, was accreted to North America, and was subsequently transported along faults to its present location (Plafker and others, 1989; Hillhouse and Coe, 1994). Some of these faults are still active. Similar tectonic, igneous, and sedimentary processes to those that formed the Mesozoic arc complex persist today in southern Alaska, building on, and deforming the Mesozoic arc. The rocks we will see on this field trip provide insights on the three-dimensional composition of the modern arc, and the processes involved in the evolution of an arc and its companion accretionary complex.

  14. Using Lymphocyte and Plasma Hsp70 as Biomarkers for Assessing Coke Oven Exposure among Steel Workers

    PubMed Central

    Yang, Xiaobo; Zheng, Jinping; Bai, Yun; Tian, Fengjie; Yuan, Jing; Sun, Jianya; Liang, Huashan; Guo, Liang; Tan, Hao; Chen, Weihong; Tanguay, Robert M.; Wu, Tangchun

    2007-01-01

    Background Hsp70, an early-response protein induced when organisms are confronted with simple or complicated environmental stresses, can act as either a cellular protector or a danger signal. Objectives The goal of this study was to evaluate levels of lymphocyte and/or plasma Hsp70 as biomarkers for assessing exposure response to complex coke oven emissions (COEs). Methods We recruited 101 coke oven workers and determined levels of polycyclic aromatic hydrocarbon (PAH) exposure, urinary 1-hydroxypyrene (1-OHP), genotoxic damage by comet assay and micronuclei test, and other markers of damage, including plasma malondialdehyde (MDA) and lactate dehydrogenase (LDH). These were compared to levels of lymphocyte (intra-cellular) and plasma (extracellular) Hsp70 using Western blots and enzyme-linked immunosorbent assays (ELISA), respectively. Results We observed a COEs-related dose-dependent increase in levels of DNA damage, micronuclei rate, MDA concentration, and LDH activity. Lymphocyte Hsp70 levels increased in the intermediate-exposure group (1.39 ± 0.88) but decreased in the high-exposure group (1.10 ± 0.55), compared with the low-exposure group. In contrast, plasma Hsp70 levels progressively increased as the dose of exposure increased. Negative correlations were seen between lymphocyte Hsp70 levels and olive tail moment and LDH activity in the intermediate- and high-exposure groups. However, we observed positive correlations between plasma Hsp70 levels and LDH activity in the low and intermediate groups. Conclusions In workers exposed to COEs, high lymphocyte Hsp70 levels may provide protection and high plasma Hsp70 levels may serve as a danger marker. Larger validation studies are needed to establish the utility of Hsp70 as a response marker. PMID:18007987

  15. Production and cross-sectional characterization of aligned co-electrospun hollow microfibrous bulk assemblies

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Zhou, Feng-Lei; The School of Materials, The University of Manchester, Manchester M13 9PL; CRUK-EPSRC Cancer Imaging Centre in Cambridge and Manchester

    2015-11-15

    The development of co-electrospun (co-ES) hollow microfibrous assemblies of an appreciable thickness is critical for many practical applications, including filtration membranes and tissue-mimicking scaffolds. In this study, thick uniaxially aligned hollow microfibrous assemblies forming fiber bundles and strips were prepared by co-ES of polycaprolactone (PCL) and polyethylene oxide (PEO) as shell and core materials, respectively. Hollow microfiber bundles were deposited on a fixed rotating disc, which resulted in non-controllable cross-sectional shapes on a macroscopic scale. In comparison, fiber strips were produced with tuneable thickness and width by additionally employing an x–y translation stage in co-ES. Scanning electron microscopy (SEM) imagesmore » of cross-sections of fiber assemblies were analyzed to investigate the effects of production time (from 0.5 h to 12 h), core flow rate (from 0.8 mL/h to 2.0 mL/h) and/or translation speed (from 0.2 mm/s to 5 mm/s) on the pores and porosity. We observed significant changes in pore size and shape with core flow rate but the influence of production time varied; five strips produced under the same conditions had reasonably good size and porosity reproducibility; pore sizes didn't vary significantly from strip bottom to surface, although the porosity gradually decreased and then returned to the initial level. - Highlights: • Hollow microfibrous assemblies based on co-electrospinning are demonstrated. • The thickness and width of co-electrospun strips were controllable. • Cross-sections of fibres had non-normally distributed pore sizes and shapes. • Cross-sections were significantly influenced by production time and flow rate. • Co-electrospun strips had reasonably good reproducible cross-sections.« less

  16. SITE DEMONSTRATION OF THE BASIC EXTRACTIVE SLUDGE TREATMENT PROCESS

    EPA Science Inventory

    The Superfund Innovative Technology Evaluation (SITE) Program, in cooperation with EPA Region 5, the Great Lakes National Program Office (GLNPO), and the U.S. Army Corps of Engineers (COE) planned and executed a pilot-scla e evaluation of the Basic Extyractive Sludge Treatment (B...

  17. 32 CFR Appendix F to Part 516 - Glossary

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC... Regulations COE: United States Army Corps of Engineers DA: Department of the Army DFARS: Defense Federal Acquisition Regulation Supplement DOD: Department of Defense DOJ: Department of Justice. In this regulation...

  18. Bench-Scale Silicone Process for Low-Cost CO{sub 2} Capture

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Vipperla, Ravikumar; Yee, Michael; Steele, Ray

    This report presents system and economic analysis for a carbon capture unit which uses an amino-silicone solvent for CO{sub 2} capture and sequestration (CCS) in a pulverized coal (PC) boiler. The amino-silicone solvent is based on GAP-1 with tri-ethylene glycol (TEG) as a co-solvent. For comparison purposes, the report also shows results for a CCS unit based on a conventional approach using mono-ethanol amine (MEA). At a steam temperature of 395 °C (743 °F), the CCS energy penalty for amino-silicone solvent is only 30.4% which compares to a 35.9% energy penalty for MEA. The increase in COE for the amino-siliconemore » solvent relative to the non-capture case is between 98% and 103% (depending on the solvent cost) which compares to an ~109% COE cost increase for MEA. In summary, the amino-silicone solvent has significant advantages over conventional systems using MEA.« less

  19. Analysis of pan-African Centres of excellence in health innovation highlights opportunities and challenges for local innovation and financing in the continent.

    PubMed

    Nwaka, Solomon; Ochem, Alexander; Besson, Dominique; Ramirez, Bernadette; Fakorede, Foluke; Botros, Sanaa; Inyang, Uford; Mgone, Charles; Adae-Mensah, Ivan; Konde, Victor; Nyasse, Barthelemy; Okole, Blessed; Guantai, Anastasia; Loots, Glaudina; Atadja, Peter; Ndumbe, Peter; Sanou, Issa; Olesen, Ole; Ridley, Robert; Ilunga, Tshinko

    2012-07-27

    A pool of 38 pan-African Centres of Excellence (CoEs) in health innovation has been selected and recognized by the African Network for Drugs and Diagnostics Innovation (ANDI), through a competitive criteria based process. The process identified a number of opportunities and challenges for health R&D and innovation in the continent: i) it provides a direct evidence for the existence of innovation capability that can be leveraged to fill specific gaps in the continent; ii) it revealed a research and financing pattern that is largely fragmented and uncoordinated, and iii) it highlights the most frequent funders of health research in the continent. The CoEs are envisioned as an innovative network of public and private institutions with a critical mass of expertise and resources to support projects and a variety of activities for capacity building and scientific exchange, including hosting fellows, trainees, scientists on sabbaticals and exchange with other African and non-African institutions.

  20. Analysis of pan-African Centres of excellence in health innovation highlights opportunities and challenges for local innovation and financing in the continent

    PubMed Central

    2012-01-01

    A pool of 38 pan-African Centres of Excellence (CoEs) in health innovation has been selected and recognized by the African Network for Drugs and Diagnostics Innovation (ANDI), through a competitive criteria based process. The process identified a number of opportunities and challenges for health R&D and innovation in the continent: i) it provides a direct evidence for the existence of innovation capability that can be leveraged to fill specific gaps in the continent; ii) it revealed a research and financing pattern that is largely fragmented and uncoordinated, and iii) it highlights the most frequent funders of health research in the continent. The CoEs are envisioned as an innovative network of public and private institutions with a critical mass of expertise and resources to support projects and a variety of activities for capacity building and scientific exchange, including hosting fellows, trainees, scientists on sabbaticals and exchange with other African and non-African institutions. PMID:22838941

  1. Potentialities of TEC topping: A simplified view of parametric effects

    NASA Technical Reports Server (NTRS)

    Morris, J. F.

    1980-01-01

    An examination of the benefits of thermionic-energy-conversion (TEC)-topped power plants and methods of increasing conversion efficiency are discussed. Reductions in the cost of TEC modules yield direct decreases in the cost of electricity (COE) from TEC-topped central station power plants. Simplified COE, overall-efficiency charts presented illustrate this trend. Additional capital-cost diminution results from designing more compact furnaces with considerably increased heat transfer rates allowable and desirable for high temperature TEC and heat pipes. Such improvements can evolve of the protection from hot corrosion and slag as well as the thermal expansion compatibilities offered by silicon-carbide clads on TEC-heating surfaces. Greater efficiencies and far fewer modules are possible with high-temperature, high-power-density TEC: This decreases capital and fuel costs much more and substantially increases electric power outputs for fixed fuel inputs. In addition to more electricity, less pollution, and lower costs, TEC topping used directly in coal-combustion products contributes balance-of-payment gains.

  2. Conceptual design of the 7 megawatt Mod-5B wind turbine generator

    NASA Technical Reports Server (NTRS)

    Douglas, R. R.

    1982-01-01

    Similar to MOD-2, the MOD-5B wind turbine generator system is designed for the sole purpose of providing electrical power for distribution by a major utility network. The objectives of the MOD-2 and MOD-5B programs are essentially identical with one important exception; the cost-of-electricity (COE) target is reduced from 4 cent/Kwhr on MOD-2 to 3 cent/Kwhr on MOD-5B, based on mid 1977 dollars and large quantity production. The MOD-5B concept studies and eventual concept selection confirmed that the program COE targets could not only be achieved but substantially bettered. Starting from the established MOD-2 technology as a base, this achievement resulted from a combination of concept changes, size changes, and design refinements. The result of this effort is a wind turbine system that can compete with conventional power generation over significant geographical areas, increasing commercial market potential by an order of magnitude.

  3. 75 FR 10347 - Federal Property Suitable as Facilities To Assist the Homeless

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-05

    ... plan, existing sanitary facilities, exact street address), providers should contact the appropriate... story stone structure, no sanitary or heating facilities, Natl Register of Historic Places Bldg. 10 VA..., State Hwy 52 Celina Co: Clay TN 38551 Landholding Agency: COE Property Number: 31199140006 Status...

  4. Phomopsis bougainvilleicola prepatellar bursitis in a renal transplant recipient

    USDA-ARS?s Scientific Manuscript database

    Pre-patellar bursitis is typically a monomicrobial bacterial infection. Rarely is a fungal cause identified. We describe a 61 year-old man who had received a renal transplant 21 months prior to presentation whose synovial fluid and surgical specimens grew Phomopsis bougainvilleicola, a pycnidial coe...

  5. 76 FR 59122 - Notice of Availability of a Draft Environmental Impact Statement in Cooperation With the North...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-09-23

    ... the north by the Northeast Cape Fear River, Holly Shelter Game Lands to the east, and Market Street... document online can contact the COE project manager or the NCDOT project manager for a CD copy of the...

  6. Phase Equilibria Modeling of Coesite Eclogite from the Sulu Belt, Eastern China

    NASA Astrophysics Data System (ADS)

    Xia, B.; Brown, M.; Wang, L.; Wang, S.; Piccoli, P. M.

    2016-12-01

    Modeling of phase equilibria and tectonic processes are essential components to understand controls on P-T paths of UHPM rocks. However, diffusion at higher temperatures (> 700 °C), and issues with determination of Fe3+ in minerals and estimating H2O contents limit our ability to determine prograde, peak P and retrograde P-T data. Also, the lack of an appropriate activity-composition model for melt in basic rocks has limited the application of phase equilibria modeling to understand partial melting associated with exhumation. Here we apply phase equilibria modeling to coesite eclogite from Yangkou to assess the influence of Fe3+ and fluid during metamorphism, monitor reactions and phase relations in eclogite during deep subduction and exhumation and investigate partial melting at HP conditions. The modeling used the THERMOCALC software and the new internally consistent thermodynamic dataset for basic rocks (http://www.metamorph.geo.uni-mainz.de/thermocalc/dataset6/index.html). Here we investigate bimineralic (gt+omp+coe/qz+ru/ilm), phengite-bearing (gt+omp+phen (2 samples, <5 vol% and >5 vol%) +coe/qz+ru/ilm) and kyanite-bearing (gt+omp+phen+ky+coe/qz+ru/ilm) eclogites. Coesite in the matrix is the hallmark of the Yangkou eclogite. For each sample, we use an iterative process to estimate the H2O and O content in the bulk composition, and then calculate a P-T pseudosection. The results suggest that some prograde information (670-770 °C, > 3.0 GPa) is retained in large garnet cores in bimineralic and phengite-bearing eclogite. The peak P-T conditions are a challenge because in the field of gt+omp+coe/qz±phen+H2O at T > 750 °C and P > 3.5 GPa mode and compositional changes are small. However, isopleths of Si in phengite suggest that the peak P could have been > 5-6 GPa. Re-equilibration of garnet and omphacite compositions occurred during exhumation, yielding P-T conditions of 700-790 °C at 3.1-2.0 GPa. Amphibolite facies metamorphism occurred at 630-710 °C, 1.3-1.2 GPa. The retrograde P-T path passes through the suprasolidus field; however, the melt produced is very low (< 5 mol%). Our work provides new quantitative P-T data for UHP eclogite in the Sulu belt and contributes to further understanding of the processes that affect deeply subducted continental crust.

  7. The ESA standard for telemetry and telecommand packet utilisation: PUS

    NASA Technical Reports Server (NTRS)

    Kaufeler, Jean-Francois

    1994-01-01

    ESA has developed standards for packet telemetry and telecommand, which are derived from the recommendations of the Inter-Agency Consultative Committee for Space Data Systems (CCSDS). These standards are now mandatory for future ESA programs as well as for many programs currently under development. However, while these packet standards address the end-to-end transfer of telemetry and telecommand data between applications on the ground and Application Processes on-board, they leave open the internal structure or content of the packets. This paper presents the ESA Packet Utilization Standard (PUS) which addresses this very subject and, as such, serves to extend and complement the ESA packet standards. The goal of the PUS is to be applicable to future ESA missions in all application areas (Telecommunications, Science, Earth Resources, microgravity, etc.). The production of the PUS falls under the responsibility of the ESA Committee for Operations and EGSE Standards (COES).

  8. Dialog: Should Faculty Merit Raises Be Linked to Enrollment Increases?

    ERIC Educational Resources Information Center

    Change, 1978

    1978-01-01

    The issue of linking faculty merit raises to enrollment increases (and therefore to student recruitment) is addressed by Mary-Anne Vetterling of Northeastern University, William E. Spellman of Coe College, Suzanne E. Lindenau of the University of Georgia, and James J. Bess of Teachers College. (LBH)

  9. Conversations with Today's Montessorians

    ERIC Educational Resources Information Center

    Montessori Life: A Publication of the American Montessori Society, 2007

    2007-01-01

    This article presents an interview with Montessorians, namely Judi Bauerlein, Jack Blessington, Dr. John Chattin-McNichols, Dr. Betsy Coe, Amy Henderson, Dr. Michele Monson, Anna P. Perry, and Bretta Weiss Wolff. In an interview, these Montessorians discuss their personal Montessori journeys and their insights on Montessori as a movement over the…

  10. 77 FR 66184 - Federal Property Suitable as Facilities To Assist the Homeless

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-11-02

    ....; bathroom; poor to fair conditions; significant deterioration on interior wood frame in several places... removal only; 36 sf.; pump house; fair conditions; access road is gated; unlocked by Ft. Gibson Lake... Project 33573 N. Shore Rd. Chamberlin SD 57325 Landholding Agency: COE Property Number: 31201240001 Status...

  11. The Human Rights Approach to Education in International Organisations

    ERIC Educational Resources Information Center

    Hufner, Klaus

    2011-01-01

    In this article, the work of three international governmental organisations (IGOs) dealing with human rights will be discussed, namely the United Nations Educational, Scientific and Cultural Organization (UNESCO), the United Nations Children's Fund (UNICEF) and the Council of Europe (CoE). In the first section, the main characteristics of the…

  12. 75 FR 52821 - Federal Property Suitable as Facilities To Assist the Homeless

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-08-27

    ... plan, existing sanitary facilities, exact street address), providers should contact the appropriate... Property Number: 97199230006 Status: Excess Comments: 310 sq. ft., 1 story stone structure, no sanitary or... Project Canoe Ridge, State Hwy 52 Celina Co: Clay TN 38551 Landholding Agency: COE Property Number...

  13. On the Causes of Effects

    ERIC Educational Resources Information Center

    Dawid, A. Philip; Faigman, David L.; Fienberg, Stephen E.

    2015-01-01

    We welcome Professor Pearl's comment on our original article, Dawid et al. Our focus there on the distinction between the "Effects of Causes" (EoC) and the "Causes of Effects" (CoE) concerned two fundamental problems, one a theoretical challenge in statistics and the other a practical challenge for trial courts. In this…

  14. The Practical Value of ASBO's COE Program.

    ERIC Educational Resources Information Center

    Larkin, Richard P.

    1997-01-01

    School business officials should realize that achieving the Government Finance Officers Association's Certificate of Excellence in Financial Reporting will not always result in a high rating. Washington, D.C. has received this award for several years while flirting with bankruptcy. This article reviews the workings of financial markets for…

  15. 77 FR 47861 - Federal Property Suitable as Facilities To Assist the Homeless

    Federal Register 2010, 2011, 2012, 2013, 2014

    2012-08-10

    ... Notice to identify Federal buildings and other real property that HUD has reviewed for suitability for... landholding agencies regarding unutilized and underutilized buildings and real property controlled by such... landholding agencies at the following addresses: COE: Mr. Scott Whiteford, Army Corps of Engineers, Real...

  16. Using GIS Tools and Environmental Scanning to Forecast Industry Workforce Needs

    ERIC Educational Resources Information Center

    Gaertner, Elaine; Fleming, Kevin; Marquez, Michelle

    2009-01-01

    The Centers of Excellence (COE) provide regional workforce data on high growth, high demand industries and occupations for use by community colleges in program planning and resource enhancement. This article discusses the environmental scanning research methodology and its application to data-driven decision making in community college program…

  17. 76 FR 68770 - Proposed Eligibility Criteria for the Centers of Excellence Program in Health Professions...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-11-07

    ... schools to recruit, train, and retain URM faculty. The COE program facilitates faculty and student...' graduates relating to minority health issues. Training students to provide health services to a significant... significant number of URM students enrolled, including individuals accepted for enrollment; (2) have been...

  18. Safe and Participatory Public Schools. Research Brief

    ERIC Educational Resources Information Center

    Rogers, John

    2010-01-01

    The California State Assembly is presently considering AB 2034 which would prohibit school districts, county offices of education (COEs), or charter schools that elect to fingerprint volunteers from allowing individuals who have been convicted of specific sex, drug or violent offenses to volunteer in schools. This policy brief aims to inform…

  19. 44 CFR 65.10 - Mapping of areas protected by levee systems.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... compaction, penetrations, other design factors affecting seepage (such as drainage layers), and other design..., compressibility of embankment soils, compressibility of foundation soils, age of the levee system, and... described in the COE manual, “Soil Mechanics Design—Settlement Analysis” (EM 1100-2-1904) must be submitted...

  20. 44 CFR 65.10 - Mapping of areas protected by levee systems.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... compaction, penetrations, other design factors affecting seepage (such as drainage layers), and other design..., compressibility of embankment soils, compressibility of foundation soils, age of the levee system, and... described in the COE manual, “Soil Mechanics Design—Settlement Analysis” (EM 1100-2-1904) must be submitted...

  1. 44 CFR 65.10 - Mapping of areas protected by levee systems.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... compaction, penetrations, other design factors affecting seepage (such as drainage layers), and other design..., compressibility of embankment soils, compressibility of foundation soils, age of the levee system, and... described in the COE manual, “Soil Mechanics Design—Settlement Analysis” (EM 1100-2-1904) must be submitted...

  2. 44 CFR 65.10 - Mapping of areas protected by levee systems.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... compaction, penetrations, other design factors affecting seepage (such as drainage layers), and other design..., compressibility of embankment soils, compressibility of foundation soils, age of the levee system, and... described in the COE manual, “Soil Mechanics Design—Settlement Analysis” (EM 1100-2-1904) must be submitted...

  3. The Effect of Cooperative Learning Techniques on College Students' Reading Comprehension

    ERIC Educational Resources Information Center

    Jalilifar, Alireza

    2010-01-01

    This study investigated the impact of Student Team Achievement Divisions (STAD) and Group Investigation (GI), which are two techniques of Cooperative Learning, on students' reading comprehension achievement of English as a Foreign Language (EFL). After administering an English Language Proficiency test (Fowler and Coe, 1976), 90 homogeneous…

  4. Examining Student Evaluations of Black College Faculty: Does Race Matter?

    ERIC Educational Resources Information Center

    Smith, Bettye P.; Hawkins, Billy

    2011-01-01

    The purpose of this study was twofold. First, to describe the undergraduate student ratings of teaching effectiveness based on the traditional 36-item end-of-course evaluation form used in the College of Education (COE) at a southeastern Research Extensive predominantly White institution. Second, using critical race theory (CRT) to compare the…

  5. Functions in Contemporary Secondary Mathematics Textbook Series in the United States

    ERIC Educational Resources Information Center

    Ross, Daniel J.

    2011-01-01

    Textbooks play a central role in US mathematics classrooms (Stein, Remillard, & Smith, 2007) and functions are a key topic in secondary mathematics (Carlson, Jacobs, Coe, Larsen, & Hsu, 2002). This study presents results from an analysis of this essential topic in the latest editions of three textbook series: the Glencoe Mathematics…

  6. Knowledge Wisdom and Networks: A Project Management Centre of Excellence Example

    ERIC Educational Resources Information Center

    Walker, Derek H. T.; Christenson, Dale

    2005-01-01

    Purpose: This conceptual paper aims to explain how "project management centres of excellence (CoEs)", a particular class of knowledge network, can be viewed as providing great potential for assisting project management (PM) teams to make wise decisions. Design/methodology/approach: The paper presents a range of knowledge network types and…

  7. 76 FR 40354 - Environmental Impacts Statements; Notice of Availability

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-07-08

    .... 20110216, Final EIS, FHWA, UT, Hyde Park/North Logan Corridor Project, Proposed 200 East Transportation Corridor between North Logan City and Hyde Park, Funding, Right-of-Way Acquisitions and US Army COE Section 404 Permit, Cache County, UT, Review Period Ends: 08/08/2011, Contact: Paul C. Ziman 801-955-3525...

  8. Faculty Instructional Computer Use Model: Differentiating Instructional and Mainstream Computer Uses

    ERIC Educational Resources Information Center

    Sahin, Ismail

    2008-01-01

    The purpose of this research study was to explore predictor variables for faculty instructional computer use. Analysis of data collected from 198 college of education (COE) faculty members indicated that instructional computer use and mainstream computer use form two strong and distinct variables. This study also proposes a faculty instructional…

  9. Implementing Wireless Mobile Instructional Labs: Planning Issues and Case Study

    ERIC Educational Resources Information Center

    McKimmy, Paul B.

    2005-01-01

    In April 2002, the Technology Advisory Committee of the University of Hawaii-Manoa College of Education (COE) prioritized the upgrade of existing instructional computer labs. Following several weeks of research and discussion, a decision was made to support wireless and mobile technologies during the upgrade. In June 2002, the first of three…

  10. Secondary Science Teachers, the Internet, and Curriculum Development: A Community of Explorers.

    ERIC Educational Resources Information Center

    Saferstein, Barry; Souviney, Randall

    1998-01-01

    In the Community of Explorers Project (CoE) high school teachers and students engaged in scientific problem solving using advanced network technology and innovative pedagogy. Analysis of e-mail indicated the important effects of organizational and occupational cultures on the application of technology in classrooms and on the development of a…

  11. 75 FR 10253 - Environmental Impact Statements and Regulations; Availability of EPA Comments

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-03-05

    ... concerns about storage, transportation and disposal of hazardous waste and radioactive wastes. EPA... wastes will need to be addressed as the project progresses. Rating EC2. EIS No. 20090378, ERP No. D-COE.... EIS No. 20100008, ERP No. D-GSA-F65079-00, International Falls Land Port of Entry Improvements Study...

  12. Cyclometalated products of [(COE)(2)RhCl](2) and 1,3-(RSCH(2))(2)C(6)H(4) (R = (t)Bu, (i)Pr) Are Dimeric. Synthesis, molecular structures, and solution dynamics of [mu-ClRh(H)(RSCH(2))(2)C(6)H(3)-2,6](2).

    PubMed

    Evans, Daniel R; Huang, Mingsheng; Seganish, W Michael; Chege, Esther W; Lam, Yiu-Fai; Fettinger, James C; Williams, Tracie L

    2002-05-20

    Two tridentate thioether pincer ligands, 1,3-(RSCH(2))(2)C(6)H(4) (R = (t)()Bu, 1a; R = (i)()Pr, 1b) underwent cyclometalation using [(COE)(2)RhCl](2) in air/moisture-free benzene at room temperature. The resultant complexes, [mu-ClRh(H)(RSCH(2))(2)C(6)H(3)-2,6](2) (R = (t)Bu, 2a; R = (i)Pr, 2b) are dimeric both in the solid state and in solution. A battery of variable-temperature one- and two-dimensional (1)H NMR experiments showed conclusively that both complexes undergo dynamic exchange in solution. Exchange between two dimeric diastereomers of 2a in solution occurred via rotation about the Rh-C(ipso) bond. The dynamic exchange of 2b was significantly more complex as an additional exchange mechanism, sulfur inversion, occurred, which resulted in the exchange between several diastereomers in solution.

  13. Digitizing Medicines for Remote Capture of Oral Medication Adherence Using Co‐encapsulation

    PubMed Central

    Peloquin, C; Santillo, F; Haubrich, R; Muttera, L; Moser, K; Savage, GM; Benson, CA; Blaschke, TF

    2017-01-01

    High‐resolution measurement of medication adherence is essential to personalized drug therapy. A US Food and Drug Administration (FDA)‐cleared device, using an edible ingestion sensor (IS), external wearable patch, and paired mobile device can detect and record ingestion events. Oral medications must be combined with an IS to generate precise “digitized‐medication” ingestion records. We developed a Good Manufacturing Practice protocol to repackage oral medications with the IS within certified Capsugel capsules, termed co‐encapsulation (CoE). A randomized bioequivalence study of CoE‐IS‐Rifamate (Isoniazid/Rifampin 150/300 mg) vs. native‐Rifamate was conducted in 12 patients with active Mycobacterium tuberculosis and demonstrated bioequivalence using the population method ratio test (95% confidence interval). Subsequently, CoE‐IS‐medications across all biopharmaceutical classes underwent in vitro dissolution testing utilizing USP and FDA guidelines. CoE‐IS medications tested met USP dissolution specifications and were equivalent to their native formulations. CoE combines oral medications with the IS without altering the quality of the native formulation, generating “digitized” medications for remote capture of dosing histories. PMID:28597911

  14. Establishing a regional network of academic centers to support decision making for new vaccine introduction in Latin America and the Caribbean: the ProVac experience.

    PubMed

    Toscano, C M; Jauregui, B; Janusz, C B; Sinha, A; Clark, A D; Sanderson, C; Resch, S; Ruiz Matus, C; Andrus, J K

    2013-07-02

    The Pan American Health Organization's ProVac Initiative, designed to strengthen national decision making regarding the introduction of new vaccines, was initiated in 2004. Central to realizing ProVac's vision of regional capacity building, the ProVac Network of Centers of Excellence (CoEs) was established in 2010 to provide research support to the ProVac Initiative, leveraging existing capacity at Latin American and Caribbean (LAC) universities. We describe the process of establishing the ProVac Network of CoEs and its initial outcomes and challenges. A survey was sent to academic, not-for-profit institutions in LAC that had recently published work in the areas of clinical decision sciences and health economic analysis. Centers invited to join the Network were selected by an international committee on the basis of the survey results. Selection criteria included academic productivity in immunization-related work, team size and expertise, successful collaboration with governmental agencies and international organizations, and experience in training and education. The Network currently includes five academic institutions across LAC. Through open dialog and negotiation, specific projects were assigned to centers according to their areas of expertise. Collaboration among centers was highly encouraged. Faculty from ProVac's technical partners were assigned as focal points for each project. The resulting work led to the development and piloting of tools, methodological guides, and training materials that support countries in assessing existing evidence and generating new evidence on vaccine introduction. The evidence generated is shared with country-level decision makers and the scientific community. As the ProVac Initiative expands to other regions of the world with support from immunization and public health partners, the establishment of other regional and global networks of CoEs will be critical. The experience of LAC in creating the current network could benefit the formation of similar structures that support evidence-based decisions regarding new public health interventions. Copyright © 2013 Elsevier Ltd. All rights reserved.

  15. Correlation of prefrontal cortical activation with changing vehicle speeds in actual driving: a vector-based functional near-infrared spectroscopy study

    PubMed Central

    Yoshino, Kayoko; Oka, Noriyuki; Yamamoto, Kouji; Takahashi, Hideki; Kato, Toshinori

    2013-01-01

    Traffic accidents occur more frequently during deceleration than during acceleration. However, little is known about the relationship between brain activation and vehicle acceleration because it has been difficult to measure the brain activation of drivers while they drive. In this study, we measured brain activation during actual driving using vector-based functional near-infrared spectroscopy. Subjects decelerated from 100 to 50 km/h (speed reduction task) and accelerated from 50 to 100 km/h (speed increase task) while driving on an expressway, in the daytime and at night. We examined correlations between average vehicle acceleration in each task and five hemodynamic indices: changes in oxygenated hemoglobin (ΔoxyHb), deoxygenated hemoglobin (ΔdeoxyHb), cerebral blood volume (ΔCBV), and cerebral oxygen exchange (ΔCOE); and the phase angle k (degrees) derived from the other hemoglobin (Hb) indices. ΔoxyHb and ΔCBV reflect changes in cerebral blood flow, whereas ΔdeoxyHb, ΔCOE, and k are related to variations in cerebral oxygen metabolism. Most of the resulting correlations with specific brain sites, for all the indices, appeared during deceleration rather than during acceleration. Faster deceleration resulted in greater increases in ΔdeoxyHb, ΔCOE, and k in the prefrontal cortex (r < −0.5, p < 0.01), in particular, in the frontal eye field, and at night, it also resulted in greater decreases in ΔoxyHb and ΔCBV in the prefrontal cortex and in the parietal lobe (r > 0.4, p < 0.01), suggesting oxygen metabolism associated with transient ischemic changes. Our results suggest that vehicle deceleration requires more brain activation, focused in the prefrontal cortex, than does acceleration. From the standpoint of the indices used, we found that simultaneous analysis of multiple hemodynamic indices was able to detect not only the blood flow components of hemodynamic responses, but also more localized frontal lobe activation involving oxygen metabolism. PMID:24399953

  16. Improving NGDC Track-line Data Quality Control

    NASA Astrophysics Data System (ADS)

    Chandler, M. T.; Wessel, P.

    2004-12-01

    Ship-board gravity, magnetic and bathymetry data archived at the National Geophysical Data Center (NGDC) represent decades of seagoing research, containing over 4,500 cruises. Cruise data remain relevent despite the prominence of satellite altimetry-derived global grids because many geologic processes remain resolvable by oceanographic research alone. Due to the tremendous investment put forth by scientists and taxpayers to compile this vast archive and the significant errors found within it, additional quality assessment and corrections are warranted. These can best be accomplished by adding to existing quality control measures at NGDC. We are currently developing open source software to provide additional quality control. Along with NGDC's current sanity checking, new data at NGDC will also be subjected to an along-track ``sniffer'' which will detect and flag suspicious data for later graphical inspection using a visual editor. If new data pass these tests, they will undergo further scrutinization using a crossover error (COE) calculator which will compare new data values to existing values at points of intersection within the archive. Data passing these tests will be deemed ``quality data`` and suitable for permanent addition to the archive, while data that fail will be returned to the source institution for correction. Crossover errors will be stored and an online COE database will be available. The COE database will allow users to apply corrections to the NGDC track-line database to produce corrected data files. At no time will the archived data itself be modified. An attempt will also be made to reduce navigational errors for pre-GPS navigated cruises. Upon completion these programs will be used to explore and model systematic errors within the archive, generate correction tables for all cruises, and to quantify the error budget in marine geophysical observations. Software will be released and these procedures will be implemented in cooperation with NGDC staff.

  17. Design of Stand-Alone Hybrid Power Generation System at Brumbun Beach Tulungagung East Java

    NASA Astrophysics Data System (ADS)

    Rahmat, A. N.; Hidayat, M. N.; Ronilaya, F.; Setiawan, A.

    2018-04-01

    Indonesian government insists to optimize the use of renewable energy resources in electricity generation. One of the efforts is launching Independent Energy Village plan. This program aims to fulfill the need of electricity for isolated or remote villages in Indonesia. In order to support the penetration of renewable energy resources in electricity generation, a hybrid power generation system is developed. The simulation in this research is based on the availability of renewable energy resources in Brumbun beach, Tulungagung, East Java. Initially, the electricity was supplied through stand-alone electricity generations which are installed at each house. Hence, the use of electricity between 5 p.m. – 9 p.m. requires high operational costs. Based on the problem above, this research is conducted to design a stand-alone hybrid electricity generation system, which may consist of diesel, wind, and photovoltaic. The design is done by using HOMER software to optimize the use of electricity from renewable resources and to reduce the operation of diesel generation. The combination of renewable energy resources in electricity generation resulted in NPC of 44.680, COE of 0,268, and CO2 emissions of 0,038 % much lower than the use of diesel generator only.

  18. Increasing the Variety of Foods Consumed by a Picky Eater: Generalization of Effects across Caregivers and Settings

    ERIC Educational Resources Information Center

    Valdimarsdottir, Hildur; Halldorsdottir, Lilja Yr; Sigurdardottir, Zuilma Gabriela

    2010-01-01

    A multiple baseline across settings was used to evaluate the effects of differential reinforcement of alternative behavior, nonremoval of the fork (Hoch, Babbitt, Coe, Krell, & Hackbert, 1994), and stimulus fading on consumption of food rejected previously. The study was conducted in two separate settings, and caregivers were trained in the…

  19. Introduction of Automation for the Production of Bilingual, Parallel-Aligned Text

    DTIC Science & Technology

    2011-10-01

    Eril~ , .. !m, lwMJI.te: :o~JSt.’pJ~’f.IJ~tJ’.J15;11t. IISpe .:c~:oe ’(1JWU’t:O’.Se ’l’tlt"S."\\Ie$11eter.e$’d~tlelow:!Milew.s ’!’ll.wll’t:Q~Ksamtj

  20. 2012 Year End Report

    DTIC Science & Technology

    2012-01-01

    introduced 2008 - Virtual classroom introduced - Established the DSTC - Received first eLearning award 2003 - Received initial COE...correspondence courses 2009 - Instructor-led courses transitioned to eLearning curriculum 2005 - First eLearning course launched 2011 - SPēD...Managing Risk” from January 9 through May 4, 2012. This eLearning course also included resident sessions at CDSE. Based on feedback from students

  1. Effects of Gas Plasma Treatments on Surface Properties of Commercial Polymer Films

    DTIC Science & Technology

    1991-04-01

    Proving Ground , MD 21005 Comander, AMC ATTN: A•COE-SC 5001 Eisenhower Ave. 001 Alexandria, VA 22333-0001 Coumander, LMCBCO ATTN: AMSLC-CG, CO, CS (In...Two coptes for OTIC will Alexandria, VA 22304-6145 b et fra $TINFO Office.) Director US Amy Material Systems Analysis Actv ATTN: DRXSY-MP 001 Aberden

  2. Issues in Performance Measurement for Military Aviation with Applications to Air Combat Maneuvering

    DTIC Science & Technology

    1986-04-04

    Systems Center 6c. ADDRESS (City, State, and ZIP Co*e) 7b. ADDRESS (City. State, and ZIP Code) 1040 Woodcock Road, Suite 227 Orlando, FL 32813-7100...NTSC TR-86-008 Vreuls, D., Obermayer, R. W., Goldstein, I. & Lauber, J. K. (1973). Measurement of trainee performance in a captive rotary- wing device

  3. Educating with Prezi: A New Presentation Paradigm for Teaching, Learning, and Leading in the Digital Age

    ERIC Educational Resources Information Center

    Safar, Ammar H.

    2015-01-01

    This longitudinal descriptive qualitative evaluation action research case study explored the reflections/experiences (i.e., their perceptions, attitudes, and feelings) of 450 pre-service teachers in the College of Education (COE) at Kuwait University (KU) over three academic years regarding the use of Prezi as a facilitative storytelling…

  4. Making Whites from the Dark Side: Teaching Whiteness Studies at San Francisco State University

    ERIC Educational Resources Information Center

    Sueyoshi, Amy

    2013-01-01

    While whiteness studies at most institutions aims to expose the persistence of white supremacy to a disbelieving audience, whiteness studies within the College of Ethnic Studies (COES) at San Francisco State University (SFSU) begins with the assumption that racism still exists. The course then traces how whiteness is constructed and fortified to…

  5. Probing Nanoscale Ferroelectricity by Ultraviolet Raman Spectroscopy

    DTIC Science & Technology

    2006-09-15

    Breaking the Maya Code (Thames & Hudson, London, rev. ed., 1999), p. 13. 11. S. D. Houston, M. D. Coe, Mexicon 25, 151 (2004). 12. K. A. Taube...in Olmec Art and Archaeology in Mesoamerica, J. E. Clark, M. E. Pye, Eds. (Yale Univ. Press, New Haven, CT, 2000), pp. 75–93. 19. K. H. Basso, N

  6. EOD and Engineers Close the Gap

    DTIC Science & Technology

    2005-03-01

    Engineers ’ Close the Gap ’ 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT...action to accomplish missions effectively in the COE. However, tomorrow’s construct will not only “ close the gap ” between EOD and engineers, it will close

  7. Colleges of Education Librarians in Nigeria: An Investigation into the Self-Perception of ICT-Related Information Literacy Skills

    ERIC Educational Resources Information Center

    Baro, Ebikabowei Emmanuel; Eze, Monica Eberechukwu

    2015-01-01

    The authors of this paper investigated the level of information communication technology-related (ICT) information literacy (IL) skills of librarians in Nigerian Colleges of Education (COE) in order to discover the challenges they face in acquiring these skills. A descriptive survey method was adopted using a questionnaire. Study participants…

  8. Intersection of Re-Designated National League for Nursing Centers of Excellence(TM) and Quality in Nursing Education

    ERIC Educational Resources Information Center

    Merriam, Deborah

    2013-01-01

    Nursing education is challenged to meet a growing demand for nurses, while substantiating the quality of the educational experience as well as the achievement of desired student outcomes. The National League for Nursing (NLN) Centers of Excellence (COE) in Nursing Education(TM) program represents high performing nursing schools which utilize…

  9. Thematization in EFL Students' Composition Writing and Its Relation to Academic Experience

    ERIC Educational Resources Information Center

    Jalilifar, Alireza

    2010-01-01

    This study made frequency and functional analysis of thematization in English students' compositions in Shahid Chamran University. Ninety students were selected and divided into three groups, followed by a homogeneity test (Fowler and Coe, 1976). An educated native speaker was also used as a criterion measure. Then, they were asked to narrate…

  10. Energy potential and early operational experience for large wind turbines

    NASA Technical Reports Server (NTRS)

    Robbins, W. H.; Thomas, R. L.

    1980-01-01

    Projections for the total potential output of large wind turbines in the U.S. are reviewed. NASA has developed nine large windpowered generators, of 100 kW, 200 kW, 2 MW, and 2.5 MW capacities, with rotors 100-300 ft in diameter, and all with horizontal axes. Approximately 214,000 sq miles of the U.S. have been determined as having substantial wind regimes and terrain suitable for large wind turbine siting. This translates into 340,000 Mod 2 (2.5 MW) wind turbines producing 4.9 quads of electricity annually, equivalent to saving 2.5 billion barrels of oil/yr. The cost of electricity is seen as the critical factor in utility acceptance of large wind turbines, and the Mod 2 machines are noted to achieve the 2-4 cents/kWh (1977 dollars) COE which is necessary. Problems such as pollution, including visual, auditory, EM, and land use difficulties are considered, and solutions are indicated.

  11. Analysis and implementation of PM sampling methodology protocols to aid in the development of an ARP (aerospace recommended practice) for aircraft non-volatile PM measurements

    NASA Astrophysics Data System (ADS)

    Catron, Brian Lowell

    Due to the growing concerns that particulate matter (PM) have on health and the environment, there is a need to include mass and number non-volatile PM measurements to current jet engine certification. This thesis looks at the necessary work required to help produce recommendations and perform background research to aid in the creation of an improved Aerospace Recommended Practice (ARP) (by the SAE E-31 Committee). This work addressed the following issues. The investigation began in the Missouri S&T Center of Excellence for Aerospace Particulate Emissions Reduction Research (COE) laboratory with an examination of the jet engine surrogate used, the miniCAST, as well as integrating it into the COE's PM measurement system. A clean PM sample line was aged by running a PM source through it until a steady state signal was measured by the instruments in order to make a recommended procedure for line conditioning as well as reconditioning. Several eductors were studied for their performance characteristics and compared against desired characteristics, which suggested a need to include a pressure relief valve to cap the sample pressure at the eductor entrance. A volatile particle remover (VPR) was studied for penetration and ability to remove volatile material. A prototype E-31 system was setup at the second alternative aviation fuel experiment (AAFEX II), which provided a direct comparison of probe tip dilution and downstream dilution and found comparable results when line loss was taken into account. Also performed at AAFEX II was a study that compared measured sample line penetration with theoretical calculations finding that theoretical calculations were an accurate alternative of measuring line loss. Two PM sampling systems were setup at an ARP demonstration and both system had similar results for both number and mass measurement. An instrument comparison was also performed that included an examination of condensation particle counter (CPC) cutoff size. It was also determined that a VPR was necessary to ensure that number instrument devices were only measuring non-volatile PM.

  12. Trajectory Optimization for Spacecraft Collision Avoidance

    DTIC Science & Technology

    2013-09-01

    Modified Set of Equinoctial Orbit Elements . AAS/AIAA 91-524," in Astrodynamics Specialist Conference, Durango, CO, 1991. [18] D. E. Kirk...these singularities, the COE are not necessarily the best set of states for numerical analysis. 2.3.3 Equinoctial Orbital Elements A third method of...completely defining an orbit is by the use of the Equinoctial Orbital Elements . This element set maintains the

  13. Recovery of Riparian Vegetation on an Intermittent Stream Following Removal of Cattle

    Treesearch

    Jerry J. Smith

    1989-01-01

    In 1984 – 1987 the recovery of riparian willows (Salix spp.) and sycamores (Platanus racemosa) was studied on two short, intermittent stream sections in a newly acquired portion of Henry W. Coe State Park in central California. Prior to removal of cattle in 1983, the plots contained mature sycamores, one young sycamore, and five...

  14. Organizational Effectiveness Information System (OEIS) User’s Manual

    DTIC Science & Technology

    1986-09-01

    SUBJECT CODES B-l C. LISTING OF VALID RESOURCE SYSTEM CODES C-l »TflerÄ*w»fi*%f*fc**v.nft; ^’.A/.V. A y.A/.AAA«•.*-A/. AAV ...the valid codes used la the Implementation and Design System. MACOM 01 COE 02 DARCOM 03 EUSA 04 FORSCOM 05 HSC 06 HQDA 07 INSCOM 08 MDW 09

  15. Colleges of Education Lecturers Attitude towards the Use of Information and Communication Technology in Nigeria

    ERIC Educational Resources Information Center

    Olafare, Festus Oladimeji; Adeyanju, Lawrence Olugbade; Fakorede, S. O. A.

    2017-01-01

    Information and Communication Technology (ICT) has transformed the global education system in the areas of teaching and learning to achieve the Sustainable Development Goals (SDGs). Lecturers in College of Education (COE) are not only supposed to use ICT towards the achievement, they are to model good use of ICT for pre-service teachers. This…

  16. 75 FR 54378 - Draft Environmental Impact Statement; Stehekin River Corridor Implementation Plan; Lake Chelan...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2010-09-07

    .... While the COE failed to secure funds to do a detailed five-year study, its emergency management team recommended extensive bank hardening with rock, and dredging of the river channel. Estimated one-time cost is... floods. Until now, the NPS has addressed problems on a case-by-case basis throughout the valley with the...

  17. The Impact of a Geographic Technologies Professional Development Institute on Middle Eastern and North African Teachers

    ERIC Educational Resources Information Center

    Benimmas, Aicha; Kerski, Joseph; Solis, Patricia

    2011-01-01

    Basic education in the Middle East and North Africa (MENA) seems to be characterized by lecture methods of instruction, a lack of interdisciplinary approaches and a disconnection with local community problems. During 2008, a "My Community, Our Earth" (MyCOE) workshop was organized in the MENA region and involved teachers of geography,…

  18. Hearing the Difference: "Mockingbird" Novel Inspires Student-Led Anti-Racism Video Project

    ERIC Educational Resources Information Center

    Coe, Cindy A.

    2017-01-01

    In this article, Cindy Coe describes how after wrapping up her eighth grade "To Kill a Mockingbird" unit, one of her students came to her about derogatory terms being used around school and expressed that she wanted to do something about it in light of their recent unit. In a meeting with the principal, the student shared her frustration…

  19. A Professional Development School in Action: Meeting the Needs of Military-Connected Students and Families

    ERIC Educational Resources Information Center

    Risberg, Sandy; Curtis, Laurie; Shivers, Lucas

    2014-01-01

    In the fall of 2011, an undergraduate student who is also a military spouse and mother of school-aged children, shared with the College of Education (COE) at Kansas State University faculty her concerns about the necessity of intentional preparation of teachers and counselors regarding the unique needs of military-connected children. From that…

  20. Annotated Bibliography of Bioassays Related to Sediment Toxicity Testing in Washington State

    DTIC Science & Technology

    1990-10-01

    effects of sediments contaminated with heavy metals, petroleum hydrocarbons , synthetic organic compounds and radionuclides. It also provides an... molluscs (adults only), echinoderm larvae and fish), and bioassay procedures with selected toxicants (metals, petrochemicals, pesticides, contaminated...reference sediment + 15 mm test sediment. Bioaccumulation tests (with same organisms) are a’so discussed. EPA/COE (U.S. Environmental Protection Agency

  1. Cultural Capital and Transnational Parenting: The Case of Ghanaian Migrants in the United States

    ERIC Educational Resources Information Center

    Coe, Cati; Shani, Serah

    2015-01-01

    What does cultural capital mean in a transnational context? In this article, Cati Coe and Serah Shani illustrate through the case of Ghanaian immigrants to the United States that the concept of cultural capital offers many insights into immigrants' parenting strategies, but that it also needs to be refined in several ways to account for the…

  2. Scoping Studies to Evaluate the Benefits of an Advanced Dry Feed System on the Use of Low-Rank Coal

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rader, Jeff; Aguilar, Kelly; Aldred, Derek

    2012-03-30

    The purpose of this project was to evaluate the ability of advanced low rank coal gasification technology to cause a significant reduction in the COE for IGCC power plants with 90% carbon capture and sequestration compared with the COE for similarly configured IGCC plants using conventional low rank coal gasification technology. GE’s advanced low rank coal gasification technology uses the Posimetric Feed System, a new dry coal feed system based on GE’s proprietary Posimetric Feeder. In order to demonstrate the performance and economic benefits of the Posimetric Feeder in lowering the cost of low rank coal-fired IGCC power with carbonmore » capture, two case studies were completed. In the Base Case, the gasifier was fed a dilute slurry of Montana Rosebud PRB coal using GE’s conventional slurry feed system. In the Advanced Technology Case, the slurry feed system was replaced with the Posimetric Feed system. The process configurations of both cases were kept the same, to the extent possible, in order to highlight the benefit of substituting the Posimetric Feed System for the slurry feed system.« less

  3. Experimental and numerical simulation of the acquisition of chemical remanent magnetization and the Thellier procedure

    NASA Astrophysics Data System (ADS)

    Shcherbakov, V. P.; Sycheva, N. K.; Gribov, S. K.

    2017-09-01

    The results of the Thellier-Coe experiments on paleointensity determination on the samples which contain chemical remanent magnetization (CRM) created by thermal annealing of titanomagnetites are reported. The results of the experiments are compared with the theoretical notions. For this purpose, Monte Carlo simulation of the process of CRM acquisition in the system of single-domain interacting particles was carried out; the paleointensity determination method based on the Thellier-Coe procedure was modeled; and the degree of paleointensity underestimation was quantitatively estimated based on the experimental data and on the numerical results. Both the experimental investigations and computer modeling suggest the following main conclusion: all the Arai-Nagata diagrams for CRM in the high-temperature area (in some cases up to the Curie temperature T c) contain a relatively long quasi-linear interval on which it is possible to estimate the slope coefficient k and, therefore, the paleointensity. Hence, if chemical magnetization (or remagnetization) took place in the course of the magnetomineralogical transformations of titanomagnetite- bearing igneous rocks during long-lasting cooling or during repeated heatings, it can lead to incorrect results in determining the intensity of the geomagnetic field in the geological past.

  4. Absolute geomagnetic intensity data from preclassic Guatemalan pottery

    NASA Astrophysics Data System (ADS)

    Alva-Valdivia, L. M.; Morales, J.; Goguitchaichvili, A.; Popenoe de Hatch, M.; Hernandez-Bernal, M. S.; Mariano-Matías, F.

    2010-05-01

    Archaeointensity results from 10 pottery fragments from the Kaminaljuyu area (14°37'N, 90°32'W)—Guatemala, whose ages range from 100 to 900 B.C., were determined in order to contribute to the incipient intensity secular variation curve for the preclassic period in Mesoamerica. Magnetic experiments including hysteresis loops, IRM-DIRM and Curie temperature analysis indicate that pseudo-single-domain magnetite and/or titanium poor titanomagnetites are responsible for the remanence. Pottery fragments were analyzed using the Coe version of the Thellier and Thellier paleointensity method. Although not numerous, our results meet with high standard, commonly accepted strict selection and acceptance criteria as attested by reasonably high Coe quality factors. The fragment mean archaeointensities range from 15 to 43 μT, and corresponding virtual axial dipole moments range from 3.6 ± 0.7 to 10.3 ± 0.9 × 10 22 Am 2. This corresponds to a mean VADM value of (7.5 ± 2.5) × 10 22 Am 2, which is close to the present day field strength. The new results obtained in this study together with those of ArcheoInt data compilation, are analyzed in context of CALS3k and ARCH3K model predictions.

  5. Efficient Dual-Site Carbon Monoxide Electro-Catalysts via Interfacial Nano-Engineering.

    PubMed

    Liu, Zhen; Huang, Zhongyuan; Cheng, Feifei; Guo, Zhanhu; Wang, Guangdi; Chen, Xu; Wang, Zhe

    2016-09-21

    Durable, highly efficient, and economic sound electrocatalysts for CO electrooxidation (COE) are the emerging key for wide variety of energy solutions, especially fuel cells and rechargeable metal-air batteries. Herein, we report the novel system of nickel-aluminum double layered hydroxide (NiAl-LDH) nanoplates on carbon nanotubes (CNTs) network. The formulation of such complexes system was to be induced through the assistance of gold nanoparticles in order to form dual-metal active sites so as to create a extended Au/NiO two phase zone. Bis (trifluoromethylsulfonyl)imide (NTf2) anion of ionic liquid electrolyte was selected to enhance the CO/O2 adsorption and to facilitate electro-catalyzed oxidation of Ni (OH)2 to NiOOH by increasing the electrophilicity of catalytic interface. The resulting neutral catalytic system exhibited ultra-high electrocatalytic activity and stability for CO electrooxidation than commercial and other reported precious metal catalysts. The turnover frequency (TOF) of the LDH-Au/CNTs COE catalyst was much higher than the previous reported other similar electrocatalysts, even close to the activity of solid-gas chemical catalysts at high temperature. Moreover, in the long-term durability testing, the negligible variation of current density remains exsisting after 1000 electrochemistry cycles.

  6. Efficient Dual-Site Carbon Monoxide Electro-Catalysts via Interfacial Nano-Engineering

    PubMed Central

    Liu, Zhen; Huang, Zhongyuan; Cheng, Feifei; Guo, Zhanhu; Wang, Guangdi; Chen, Xu; Wang, Zhe

    2016-01-01

    Durable, highly efficient, and economic sound electrocatalysts for CO electrooxidation (COE) are the emerging key for wide variety of energy solutions, especially fuel cells and rechargeable metal−air batteries. Herein, we report the novel system of nickel−aluminum double layered hydroxide (NiAl-LDH) nanoplates on carbon nanotubes (CNTs) network. The formulation of such complexes system was to be induced through the assistance of gold nanoparticles in order to form dual-metal active sites so as to create a extended Au/NiO two phase zone. Bis (trifluoromethylsulfonyl)imide (NTf2) anion of ionic liquid electrolyte was selected to enhance the CO/O2 adsorption and to facilitate electro-catalyzed oxidation of Ni (OH)2 to NiOOH by increasing the electrophilicity of catalytic interface. The resulting neutral catalytic system exhibited ultra-high electrocatalytic activity and stability for CO electrooxidation than commercial and other reported precious metal catalysts. The turnover frequency (TOF) of the LDH-Au/CNTs COE catalyst was much higher than the previous reported other similar electrocatalysts, even close to the activity of solid-gas chemical catalysts at high temperature. Moreover, in the long-term durability testing, the negligible variation of current density remains exsisting after 1000 electrochemistry cycles. PMID:27650532

  7. Efficient Dual-Site Carbon Monoxide Electro-Catalysts via Interfacial Nano-Engineering

    NASA Astrophysics Data System (ADS)

    Liu, Zhen; Huang, Zhongyuan; Cheng, Feifei; Guo, Zhanhu; Wang, Guangdi; Chen, Xu; Wang, Zhe

    2016-09-01

    Durable, highly efficient, and economic sound electrocatalysts for CO electrooxidation (COE) are the emerging key for wide variety of energy solutions, especially fuel cells and rechargeable metal-air batteries. Herein, we report the novel system of nickel-aluminum double layered hydroxide (NiAl-LDH) nanoplates on carbon nanotubes (CNTs) network. The formulation of such complexes system was to be induced through the assistance of gold nanoparticles in order to form dual-metal active sites so as to create a extended Au/NiO two phase zone. Bis (trifluoromethylsulfonyl)imide (NTf2) anion of ionic liquid electrolyte was selected to enhance the CO/O2 adsorption and to facilitate electro-catalyzed oxidation of Ni (OH)2 to NiOOH by increasing the electrophilicity of catalytic interface. The resulting neutral catalytic system exhibited ultra-high electrocatalytic activity and stability for CO electrooxidation than commercial and other reported precious metal catalysts. The turnover frequency (TOF) of the LDH-Au/CNTs COE catalyst was much higher than the previous reported other similar electrocatalysts, even close to the activity of solid-gas chemical catalysts at high temperature. Moreover, in the long-term durability testing, the negligible variation of current density remains exsisting after 1000 electrochemistry cycles.

  8. Relative sea-level rise as indicated by gage data along the Mississippi and Alabama Gulf Coasts

    USGS Publications Warehouse

    Van Wilson, K.

    2004-01-01

    Global warming, or the increasing of earth's temperatures, leads to rising sea level as polar ice caps and mountain glaciers melt and ocean water undergoes thermal expansion. Tidal records collected by the U.S. Army Corps of Engineers (COE), Mobile District, at Gulfport, Biloxi, and Pascagoula, Mississippi, and at Mobile, Alabama, indicate trends of water-surface elevations increasing with time (relative sea-level rise). The trends indicated by the COE data were compared to relative sea-level trends indicated by the National Ocean Survey gages in the Gulf of Mexico. The average global rate of sea level rise has been suggested to approach about 2 mm/yr (0.007 ft/yr). Some leading scientists have suggested rates of sea level rise that are greater than 2 mm/yr, when accounting for effects of greenhouse gas emissions. As the sea level rises and inundates the coastal plain, structures along the existing coast and structures located in the back bays of estuaries will be even more adversely affected by future flooding. Also, if the land surface adjacent to the water also sinks due to soil compaction and other geologic processes (collectively call subsidence), additional land will be inundated. Copyright ASCE 2004.

  9. Techno-Economic and dynamic analysis of low velocity wind turbines for rural electrification in agricultural area of Ratchaburi Province, Thailand

    NASA Astrophysics Data System (ADS)

    Lipirodjanapong, Sumate; Namboonruang, Weerapol

    2017-07-01

    This paper presents the analysis of potential wind speed of electrical power generating using for agriculture in Ratchaburi province, Thailand. The total area is 1,900 square kilometers. First of all, the agriculture electrical load (AEL) data was investigated from all farming districts in Ratchaburi. Subsequently, the load data was analyzed and classified by the load power and energy consumption at individual district. The wind turbine generator (WTG) at capacity rate of 200w, 500w, 1,000w, and 2,000w were adopted to implement for the AEL in each area at wind speed range of 3 to 6 m/s. This paper shows the approach based on the wind speed at individual district to determine the capacity of WTG using the capacitor factor (CF) and the cost of energy (COE) in baht per unit under different WTG value rates. Ten locations for wind station installations are practical investigated. Results show that for instance, the Damnoen Sa-duak (DN-04) one of WTG candidate site is identically significant for economic investment of installing rated WTG. The results of COE are important to determine whether a wind site is good or not.

  10. Final Techno-Economic Analysis of 550 MWe Supercritical PC Power Plant CO 2 Capture with Linde-BASF Advanced PCC Technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Bostick, Devin; Stoffregen, Torsten; Rigby, Sean

    This topical report presents the techno-economic evaluation of a 550 MWe supercritical pulverized coal (PC) power plant utilizing Illinois No. 6 coal as fuel, integrated with 1) a previously presented (for a subcritical PC plant) Linde-BASF post-combustion CO 2 capture (PCC) plant incorporating BASF’s OASE® blue aqueous amine-based solvent (LB1) [Ref. 6] and 2) a new Linde-BASF PCC plant incorporating the same BASF OASE® blue solvent that features an advanced stripper interstage heater design (SIH) to optimize heat recovery in the PCC process. The process simulation and modeling for this report is performed using Aspen Plus V8.8. Technical information frommore » the PCC plant is determined using BASF’s proprietary thermodynamic and process simulation models. The simulations developed and resulting cost estimates are first validated by reproducing the results of DOE/NETL Case 12 representing a 550 MWe supercritical PC-fired power plant with PCC incorporating a monoethanolamine (MEA) solvent as used in the DOE/NETL Case 12 reference [Ref. 2]. The results of the techno-economic assessment are shown comparing two specific options utilizing the BASF OASE® blue solvent technology (LB1 and SIH) to the DOE/NETL Case 12 reference. The results are shown comparing the energy demand for PCC, the incremental fuel requirement, and the net higher heating value (HHV) efficiency of the PC power plant integrated with the PCC plant. A comparison of the capital costs for each PCC plant configuration corresponding to a net 550 MWe power generation is also presented. Lastly, a cost of electricity (COE) and cost of CO 2 captured assessment is shown illustrating the substantial cost reductions achieved with the Linde-BASF PCC plant utilizing the advanced SIH configuration in combination with BASF’s OASE® blue solvent technology as compared to the DOE/NETL Case 12 reference. The key factors contributing to the reduction of COE and the cost of CO 2 captured, along with quantification of the magnitude of the reductions achieved by each of these factors, are also discussed. Additionally, a high-level techno-economic analysis of one more highly advanced Linde-BASF PCC configuration case (LB1-CREB) is also presented to demonstrate the significant impact of innovative PCC plant process design improvements on further reducing COE and cost of CO 2 captured for overall plant cost and performance comparison purposes. Overall, the net efficiency of the integrated 550 MWe supercritical PC power plant with CO 2 capture is increased from 28.4% with the DOE/NETL Case 12 reference to 30.9% with the Linde-BASF PCC plant previously presented utilizing the BASF OASE® blue solvent [Ref. 6], and is further increased to 31.4% using Linde-BASF PCC plant with BASF OASE® blue solvent and an advanced SIH configuration. The Linde-BASF PCC plant incorporating the BASF OASE® blue solvent also results in significantly lower overall capital costs, thereby reducing the COE and cost of CO 2 captured from $147.25/MWh and $56.49/MT CO 2, respectively, for the reference DOE/NETL Case 12 plant, to $128.49/MWh and $41.85/MT CO 2 for process case LB1, respectively, and $126.65/MWh and $40.66/MT CO 2 for process case SIH, respectively. With additional innovative Linde-BASF PCC process configuration improvements, the COE and cost of CO2 captured can be further reduced to $125.51/MWh and $39.90/MT CO 2 for LB1-CREB. Most notably, the Linde-BASF process options presented here have already demonstrated the potential to lower the cost of CO2 captured below the DOE target of $40/MT CO 2 at the 550 MWe scale for second generation PCC technologies.« less

  11. Intelligence, mapping, and geospatial exploitation system (IMAGES)

    NASA Astrophysics Data System (ADS)

    Moellman, Dennis E.; Cain, Joel M.

    1998-08-01

    This paper provides further detail to one facet of the battlespace visualization concept described in last year's paper Battlespace Situation Awareness for Force XXI. It focuses on the National Imagery and Mapping Agency (NIMA) goal to 'provide customers seamless access to tailorable imagery, imagery intelligence, and geospatial information.' This paper describes Intelligence, Mapping, and Geospatial Exploitation System (IMAGES), an exploitation element capable of CONUS baseplant operations or field deployment to provide NIMA geospatial information collaboratively into a reconnaissance, surveillance, and target acquisition (RSTA) environment through the United States Imagery and Geospatial Information System (USIGS). In a baseplant CONUS setting IMAGES could be used to produce foundation data to support mission planning. In the field it could be directly associated with a tactical sensor receiver or ground station (e.g. UAV or UGV) to provide near real-time and mission specific RSTA to support mission execution. This paper provides IMAGES functional level design; describes the technologies, their interactions and interdependencies; and presents a notional operational scenario to illustrate the system flexibility. Using as a system backbone an intelligent software agent technology, called Open Agent ArchitectureTM (OAATM), IMAGES combines multimodal data entry, natural language understanding, and perceptual and evidential reasoning for system management. Configured to be DII COE compliant, it would utilize, to the extent possible, COTS applications software for data management, processing, fusion, exploitation, and reporting. It would also be modular, scaleable, and reconfigurable. This paper describes how the OAATM achieves data synchronization and enables the necessary level of information to be rapidly available to various command echelons for making informed decisions. The reasoning component will provide for the best information to be developed in the timeline available and it will also provide statistical pedigree data. This pedigree data provides both uncertainties associated with the information and an audit trail cataloging the raw data sources and the processing/exploitation applied to derive the final product. Collaboration provides for a close union between the information producer(s)/exploiter(s) and the information user(s) as well as between local and remote producer(s)/exploiter(s). From a military operational perspective, IMAGES is a step toward further uniting NIMA with its customers and further blurring the dividing line between operational command and control (C2) and its supporting intelligence activities. IMAGES also provides a foundation for reachback to remote data sources, data stores, application software, and computational resources for achieving 'just-in- time' information delivery -- all of which is transparent to the analyst or operator employing the system.

  12. National Environmental Change Information System Case Study

    NASA Technical Reports Server (NTRS)

    Goodman, S. J.; Ritschard, R.; Estes, M. G., Jr.; Hatch, U.

    2001-01-01

    The Global Hydrology and Climate Center and NASA's Marshall Space Flight Center conducted a fact-finding case study for the Data Management Working Group (DMWG), now referred to as the Data and Information Working Group (DIWG), of the U.S. Global Change Research Program (USGCRP) to determine the feasibility of an interagency National Environmental Change Information System (NECIS). In order to better understand the data and information needs of policy and decision makers at the national, state, and local level, the DIWG asked the case study team to choose a regional water resources issue in the southeastern United States that had an impact on a diverse group of stakeholders. The southeastern United States was also of interest because the region experiences interannual climatic variations and impacts due to El Nino and La Nina. Jointly, with input from the DIWG, a focus on future water resources planning in the Apalachicola-Chattahoochee-Flint (ACF) River basins of Alabama, Georgia, and Florida was selected. A tristate compact and water allocation formula is currently being negotiated between the states and U.S. Army Corps of Engineers (COE) that will affect the availability of water among competing uses within the ACF River basin. All major reservoirs on the ACF are federally owned and operated by the U.S. Army COE. A similar two-state negotiation is ongoing that addresses the water allocations in the adjacent Alabama-Coosa-Tallapoosa (ACT) River basin, which extends from northwest Georgia to Mobile Bay. The ACF and ACT basins are the subject of a comprehensive river basin study involving many stakeholders. The key objectives of this case study were to identify specific data and information needs of key stakeholders in the ACF region, determine what capabilities are needed to provide the most practical response to these user requests, and to identify any limitations in the use of federal data and information. The NECIS case study followed the terms of reference developed by the interagency DIWG. The case study "lessons learned" and "key findings" offer guidelines and considerations to the DMWG for the development and implementation of a NECIS that would support the data and information needs of policy and decision makers at the national, state, and local level.

  13. The European Charter for Regional or Minority Languages: A "Magnum Opus" or an Incomplete "Modus Vivendi?"

    ERIC Educational Resources Information Center

    Soldat-Jaffe, Tatjana

    2015-01-01

    This article investigates to what extent the European Union (EU) has the means to protect minority and regional languages in the EU, looking at the ways three different bodies of the EU, the European Parliament (EP), the Council of Europe (CoE) and the European Charter for Regional or Minority Languages (ECRML) differ in handling language…

  14. Students' Perspectives of the Impact of Online Streaming Media on Teaching and Learning at the College of Education at Kuwait University

    ERIC Educational Resources Information Center

    Safar, Ammar; Alkhezzi, Fahad

    2016-01-01

    The objective of this study was to investigate the perspectives of pre-service and in-service teachers in the College of Education (COE) at Kuwait University (KU) on the use of online streaming media services as a facilitative and innovative tool for teaching, learning, professional development, and teacher preparation. Five research questions…

  15. Applications of Nonlinear Control Using the State-Dependent Riccati Equation.

    DTIC Science & Technology

    1995-12-01

    method, and do not address noise rejection or robustness issues. xi Applications of Nonlinear Control Using the State-Dependent Riccati Equation I...construct a stabilizing nonlinear feedback controller. This method will be referred to as nonlinear quadratic regulation (NQR). The original intention...involves nding a state-dependent coe- cient (SDC) linear structure for which a stabilizing nonlinear feedback controller can be constructed. The

  16. Career Skills Enhancement Program (CSEP). A National Workplace Literacy Program, Final Report To Cover Activities April 1, 1990-September 30, 1991.

    ERIC Educational Resources Information Center

    Gray, Brenda

    The Career Skills Enhancement Program (CSEP) was a National Workplace Literacy Program offered to Santa Clara County (California) Office of Education (COE) employees. A job skills study involved personal interviews, job shadowing, and examination of job descriptions and materials used by employees. Based on the study and initial needs assessment,…

  17. Integrated active fire retrievals and biomass burning emissions using complementary near-coincident ground, airborne and spaceborne sensor data

    Treesearch

    Wilfrid Schroeder; Evan Ellicott; Charles Ichoku; Luke Ellison; Matthew B. Dickinson; Roger D. Ottmar; Craig Clements; Dianne Hall; Vincent Ambrosia; Robert Kremens

    2013-01-01

    Ground, airborne and spaceborne data were collected for a 450 ha prescribed fire implemented on 18 October 2011 at the Henry W. Coe State Park in California. The integration of various data elements allowed near-coincident active fire retrievals to be estimated. The Autonomous Modular Sensor-Wildfire (AMS) airborne multispectral imaging system was used as a bridge...

  18. Teacher Learning in Changing Professional Contexts: Bhutanese Teacher Educators and the Educating for GNH Initiative

    ERIC Educational Resources Information Center

    Gyamtso, Deki C.; Sherab, Kezang; Maxwell, T. W.

    2017-01-01

    This study was conducted in the two teacher education colleges (CoEs) of the Royal University of Bhutan. It was intended to fill the knowledge gap of teacher educators' reactions to the Educating for Gross National Happiness (EdGNH) policy introduced in Bhutan in 2010. EdGNH is recognized as one of the most critical and comprehensive attempts to…

  19. Adaptive Interfaces

    DTIC Science & Technology

    1991-03-01

    Project Engineer: Sharon M. Walter/COES/(315) 330-7650 Prime Contractor: lIT Research Institute (IITRI) 12a. DISTRIBUTION/AVAILABIUTY STATEMENT 12b...F30602- 87-D-0094. This contract is with IIT Research Institute (IITRI) and is sponsored by the Rome Air Development Center. The work was performed by... Research Institute (IITRI) and Rome Air Development Center (RADC) this Final Report for Project 7288, Adaptive Interfaces, Task A. This report is

  20. Cross-sectional study of variables associated with length of stay and ICU need in open Roux-En-Y gastric bypass surgery for morbid obese patients: an exploratory analysis based on the Public Health System administrative database (Datasus) in Brazil.

    PubMed

    Asano, Elio Fernando; Rasera, Irineu; Shiraga, Elisabete Cristina

    2012-12-01

    This is an exploratory analysis of potential variables associated with open Roux-en-Y gastric bypass (RYGB) surgery hospitalization resource use pattern. Cross-sectional study based on an administrative database (DATASUS) records. Inclusion criteria were adult patients undergoing RYGB between Jan/2008 and Jun/2011. Dependent variables were length of stay (LoS) and ICU need. Independent variables were: gender, age, region, hospital volume, surgery at certified center of excellence (CoE) by the Surgical Review Corporation (SRC), teaching hospital, and year of hospitalization. Univariate and multivariate analysis (logistic regression for ICU need and linear regression for length of stay) were performed. Data from 13,069 surgeries were analyzed. In crude analysis, hospital volume was the most impactful variable associated with log-transformed LoS (1.312 ± 0.302 high volume vs. 1.670 ± 0.581 low volume, p < 0.001), whereas for ICU need it was certified CoE (odds ratio (OR), 0.016; 95% confidence interval (CI), 0.010-0.026). After adjustment by logistic regression, certified CoE remained as the strongest predictor of ICU need (OR, 0.011; 95% CI, 0.007-0.018), followed by hospital volume (OR, 3.096; 95% CI, 2.861-3.350). Age group, male gender, and teaching hospital were also significantly associated (p < 0.001). For log-transformed LoS, final model includes hospital volume (coefficient, -0.223; 95% CI, -0.250 to -0.196) and teaching hospital (coefficient, 0.375; 95% CI, 0.351-0.398). Region of Brazil was not associated with any of the outcomes. High-volume hospital was the strongest predictor for shorter LoS, whereas SRC certification was the strongest predictor of lower ICU need. Public health policies targeting an increase of efficiency and patient access to the procedure should take into account these results.

  1. Matuyama/Brunhes Polarity Transition in Owens Lake, CA, Sediment

    NASA Astrophysics Data System (ADS)

    Liddicoat, Joseph; Kravchinsky, Vadim

    2014-05-01

    The complexity of the Matuyama/Brunhes (M/B) polarity transition is becoming better understood from investigations of volcanic rocks (Coe et al., 2004), loess (Jin et al., 2012; Evans et al., 2011; Kravchinsky, 2013), and marine (Clement and Opdyke, 1982; Hartl and Tauxe, 1996; Macri et al., 2010) and lacustrine (Valet et al., 1988; Sagnotti et al., 2013) sediments. The transition appears to include a brief interval of normal polarity prior to the entry into the Brunhes Normal Chron (Coe et al., 2004; Jin et al., 2012; Evans et al., 2011), and the transition has Virtual Geomagnetic Poles rapidly moving from the Southern Hemisphere to the Northern Hemisphere (Coe et al., 2004; Jin et al., 2012; Evans et al., 2011; Sagnotti et al., 2013). The M/B polarity transition is recorded in exposed Pleistocene lake sediments near Bishop, CA, where the brief interval of normal polarity noted above is present and the change from full reverse to full normal polarity occurs rapidly. The brief interval of normal polarity is recorded at two sites separated laterally by about 150 m and is in single hand samples measured at vertical spacing of 2.0-2.5 cm using six samples per measured level and alternating field demagnetization at 20 mT (Liddicoat, 1993, Table 1 and Fig. 8). The siltstone is unweathered glacial flour from the Sierra Nevada that borders the western side of Owens Valley where the sediments were deposited in Owens Lake. In the siltstone, the majority of the samples have a percentage of about 60 percent where the grain diameter is less than 63 micrometres, and in those samples there is about a five percent fraction when the diameter is two micrometres or less. The Total Inorganic Carbon in most samples is about 0.25 percent (Bergeron, 2013), and magnetite is the dominant carrier of the magnetization (Liddicoat, 1993). The palaeomagnetic directions recording the terminus of the full M/B transition, which occurs before the field intensity is completely recovered, spans no more than 35 cm of siltstone at each of two localities about a km apart. We will present the results of a continuing palaeomagnetic investigation of the M/B transition at this locality.

  2. Investigation of carbon dioxide emission in China by primary component analysis.

    PubMed

    Zhang, Jing; Wang, Cheng-Ming; Liu, Lian; Guo, Hang; Liu, Guo-Dong; Li, Yuan-Wei; Deng, Shi-Huai

    2014-02-15

    Principal component analysis (PCA) is employed to investigate the relationship between CO2 emissions (COEs) stemming from fossil fuel burning and cement manufacturing and their affecting factors. Eight affecting factors, namely, Population (P), Urban Population (UP); the Output Values of Primary Industry (PIOV), Secondary Industry (SIOV), and Tertiary Industry (TIOV); and the Proportions of Primary Industry's Output Value (PPIOV), Secondary Industry's Output Value (PSIOV), and Tertiary Industry's Output Value (PTIOV), are chosen. PCA is employed to eliminate the multicollinearity of the affecting factors. Two principal components, which can explain 92.86% of the variance of the eight affecting factors, are chosen as variables in the regression analysis. Ordinary least square regression is used to estimate multiple linear regression models, in which COEs and the principal components serve as dependent and independent variables, respectively. The results are given in the following. (1) Theoretically, the carbon intensities of PIOV, SIOV, and TIOV are 2573.4693, 552.7036, and 606.0791 kt per one billion $, respectively. The incomplete statistical data, the different statistical standards, and the ideology of self sufficiency and peasantry appear to show that the carbon intensity of PIOV is higher than those of SIOV and TIOV in China. (2) PPIOV, PSIOV, and PTIOV influence the fluctuations of COE. The parameters of PPIOV, PSIOV, and PTIOV are -2706946.7564, 2557300.5450, and 3924767.9807 kt, respectively. As the economic structure of China is strongly tied to technology level, the period when PIOV plays the leading position is characterized by lagging technology and economic developing. Thus, the influence of PPIOV has a negative value. As the increase of PSIOV and PTIOV is always followed by technological innovation and economic development, PSIOV and PTIOV have the opposite influence. (3) The carbon intensities of P and UP are 1.1029 and 1.7862 kt per thousand people, respectively. The carbon intensity of the rural population can be inferred to be lower than 1.1029 kt per thousand people. The characteristics of poverty and the use of bio-energy in rural areas result in a carbon intensity of the rural population that is lower than that of P. Copyright © 2013 Elsevier B.V. All rights reserved.

  3. Comparison Of Intake Gate Closure Methods At Lower Granite, Little Goose, Lower Monumental, And Mcnary Dams Using Risk-Based Analysis

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gore, Bryan F.; Blackburn, Tyrone R.; Heasler, Patrick G.

    2001-01-19

    The objective of this report is to compare the benefits and costs of modifications proposed for intake gate closure systems at four hydroelectric stations on the Lower Snake and Upper Columbia Rivers in the Walla Walla District that are unable to meet the COE 10-minute closure rule due to the installation of fish screens. The primary benefit of the proposed modifications is to reduce the risk of damage to the station and environs when emergency intake gate closure is required. Consequently, this report presents the results and methodology of an extensive risk analysis performed to assess the reliability of powerhousemore » systems and the costs and timing of potential damages resulting from events requiring emergency intake gate closure. As part of this analysis, the level of protection provided by the nitrogen emergency closure system was also evaluated. The nitrogen system was the basis for the original recommendation to partially disable the intake gate systems. The risk analysis quantifies this protection level.« less

  4. Hurricane Andrew: Impact on hazardous waste management

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Kastury, S.N.

    1993-03-01

    On August 24, 1992, Hurricane Andrew struck the eastern coast of South Florida with winds of 140 mph approximately and a storm surge of 15 ft. The Florida Department of Environmental Regulation finds that the Hurricane Andrew caused a widespread damage throughout Dade and Collier County as well as in Broward and Monroe County and has also greatly harmed the environment. The Department has issued an emergency final order No. 92-1476 on August 26, 1992 to address the environmental cleanup and prevent any further spills of contaminants within the emergency area. The order authorizes the local government officials to designatemore » certain locations in areas remote from habitation for the open burning in air certain incinerators of hurricane generated yard trash and construction and demolition debris. The Department staff has assisted the county and FEMA staff in establishing procedures for Hazardous Waste Management, Waste Segregation and disposal and emergency responses. Local governments have issued these burn permits to public agencies including FDOT and Corps of Engineering (COE). Several case studies will be discussed on the Hazardous Waste Management at this presentation.« less

  5. Automated Design of a High-Velocity Channel

    DTIC Science & Technology

    2006-05-01

    using Newton’s method. 2.2.2 Groundwater Applications Optimization methods are also very useful for solving groundwater problems. Townley et al... Townley 85] apply present computational algorithms to steady and transient models for groundwater °ow. The aquifer storage coe±cients, transmissivities...Reliability Analysis", Water Resources Research, Vol. 28, No. 12, December 1992, pp. 3269-3280. [ Townley 85] Townley , L. R. and Wilson, J. L

  6. State of Washington Aquatic Plant Management Program. Supplement

    DTIC Science & Technology

    1991-03-01

    which are sticky fluids such as inverting oils and polymers, or fibers, which enhance clinging to submersed vegetation (Getsinger and Westerdahl , 1988...primarily by photolysis, by biodegradation, and least significantly by volatilization ( Westerdahl and Getsinger 1988). Thus, there is no reason for... Westerdahl . 1988. Hiscellaneous-Paper A-88-1, Waterways Experimental Station, COE, Vicksburg, MS, 24 pp. Gibbons, M.V., H.L. Gibbons, and R. Pine:. 1987. 1986

  7. RELICS Discovery of a Probable Lens-magnified SN behind Galaxy Cluster Abell 1763

    NASA Astrophysics Data System (ADS)

    Rodney, S.; Coe, D.; Bradley, L.; Strolger, L.; Brammer, G.; Avila, R.; Ryan, R.; Ogaz, S.; Riess, A.; Sharon, K.; Johnson, T.; Paterno-Mahler, R.; Molino, A.; Graham, M.; Kelly, P.; Filippenko, A.; Frye, B.; Foley, R.; Schmidt, K.; Umetsu, K.; Czakon, N.; Weiner, B.; Stark, D.; Mainali, R.; Zitrin, A.; Sendra, I.; Graur, O.; Grillo, C.; Hjorth, J.; Selsing, J.; Christensen, L.; Rosati, P.; Nonino, M.; Balestra, I.; Vulcani, B.; McCully, C.; Dawson, W.; Bouwens, R.; Lam, D.; Trenti, M.; Nunez, D. Carrasco; Matheson, T.; Merten, J.; Jha, S.; Jones, C.; Andrade-Santos, F.; Salmon, B.; Bradac, M.; Hoag, A.; Huang, K.; Wang, X.; Oesch, P.

    2016-07-01

    We report the discovery of a likely supernova (SN) in the background field of the galaxy cluster Abell 1763 (a.k.a. RXC J1335.3+4059, ZwCl 1333.7+4117). The SN candidate was detected in Hubble Space Telescope (HST) observations collected on June 17, 2016 as part of the Reionization Lensing Cluster Survey (RELICS, HST program ID: 14096, PI: D.Coe).

  8. An Evaluation of an Attitudinal Model to Measure the Potential for Combat Effectiveness of U.S. Air Force Organizations.

    DTIC Science & Technology

    1982-09-01

    Fight Combat Effectiveness Organizational Assessment Package Morale Combat Effectiveness Model Cohesion Leadership 20. AIISTRACT (COe/Mie do ,eae aide If...of combat readiness. The major psychosocial dimensions which contribute to combat effectiveness of a military unit (morale leadership , cohesion, and...psychosocial dimensions in the combat effectiveness model (morale, leadership , and cohesion) in addition to training, logistics, alienation, and work group

  9. Recombinant infectious hematopoietic necrosis virus expressing infectious pancreatic necrosis virus VP2 protein induces immunity against both pathogens.

    PubMed

    Guo, Mengting; Shi, Wen; Wang, Yanxue; Wang, Yuting; Chen, Yaping; Li, Dechuan; Ren, Xuanyu; Hua, Xiaojing; Tang, Lijie; Li, Yijing; Liu, Min

    2018-04-21

    Infectious hematopoietic necrosis virus (IHNV) and infectious pancreatic necrosis virus (IPNV) are typical pathogens of rainbow trout. Their co-infection is also common, which causes great economic loss in juvenile salmon species. Although vaccines against IHNV and IPNV have been commercialized in many countries, the prevalence of IHNV and IPNV is still widespread in modern aquaculture. In the present study, two IHNV recombinant viruses displaying IPNV VP2 protein (rIHNV-IPNV VP2 and rIHNV-IPNV VP2COE) were generated using the RNA polymerase Ⅱ system to explore the immunogenicity of IHNV and IPNV. The recombinant IHNV viruses were stable, which was confirmed by sequencing, indirect immunofluorescence assay, western blotting, transmission electron microscopy and viral growth curve assay. IHNV and IPNV challenge showed that the recombinant viruses had high protection rates against IHNV and IPNV with approximately 65% relative percent survival rates. Rainbow trout (mean weight 20 g) vaccinated with these two recombinant viruses showed a high level of antibodies against IHNV and IPNV infection. Taken together, our findings demonstrate that rIHNV-IPNV VP2 and rIHNV-IPNV VP2COE might be promising vaccine candidates against IHNV and IPNV. Copyright © 2018. Published by Elsevier Ltd.

  10. DOE/NETL's phase II mercury control technology field testing program: preliminary economic analysis of activated carbon injection.

    PubMed

    Jones, Andrew P; Hoffmann, Jeffrey W; Smith, Dennis N; Feeley, Thomas J; Murphy, James T

    2007-02-15

    Based on results of field testing conducted by the U.S. Department of Energy's National Energy Technology Laboratory (DOE/NETL), this article provides preliminary costs for mercury control via conventional activated carbon injection (ACI), brominated ACI, and conventional ACI coupled with the application of a sorbent enhancement additive (SEA) to coal prior to combustion. The economic analyses are reported on a plant-specific basis in terms of the cost required to achieve low (50%), mid (70%), and high (90%) levels of mercury removal "above and beyond" the baseline mercury removal achieved by existing emission control equipment. In other words, the levels of mercury control are directly attributable to ACI. Mercury control costs via ACI have been amortized on a current dollar basis. Using a 20-year book life, levelized costs for the incremental increase in cost of electricity (COE), expressed in mills per kilowatt-hour (mills/kWh), and the incremental cost of mercury control, expressed in dollars per pound of mercury removed ($/lb Hg removed), have been calculated for each level of ACI mercury control. For this analysis, the increase in COE varied from 0.14 mills/kWh to 3.92 mills/kWh. Meanwhile, the incremental cost of mercury control ranged from $3810/lb Hg removed to $166000/lb Hg removed.

  11. Conjugated Oligoelectrolytes Increase Current Response and Organic Containment Removal in Wastewater Microbial Fuel Cells

    DTIC Science & Technology

    2012-01-01

    certain COEs have been demonstrated to sponta- neously insert into liposomes and within the membranes of yeast .14 The driving force for this...ofDSSN+ and a cartoon illustration of its incorporation into a cell membrane. Introduction of yeast modified withDSSN+ into microbial fuel cells (MFCs...leads to an increase of generated current, compared to unmodified yeast , which suggests improved interaction with the charge-collecting electrode.14

  12. Evaluating and Mitigating Software Supply Chain Security Risks

    DTIC Science & Technology

    2010-05-01

    is returned for all employees. The risk associated with this defect is high; variants of it have been used in attacks that caused credit card data to...via Common Access Card (CAC) readers). 29 | CMU/SEI-2010-TN-016 4.2.1 Supplier Capability Because the project is already in development, the...ClearCase, Windows, Linux and Solaris, network administration, TCP/IP, X/Motif, DII COE, Simple Net- work Management Protocol (SNMP), Agent Technology

  13. Neuro-Triggered Training.

    DTIC Science & Technology

    1992-04-30

    Avnalabiliy Co~e ’Dst Special The views and conclusions in this document am those of the aunots and should not be intepreted as necesnuily repesenmg the...accuracy and the adaptive error tolerance. We have set up a small new recording room for this project and cleared it of 60-Hz electromagnetic noise...stimuli sounded alike. In the semantic condition, subjects were required to decide if the high frequency, open-class monosyllabic words were opposite or not

  14. Software Support Measurement and Estimating for Oracle Database Applications Using Mark II Function Points

    DTIC Science & Technology

    1992-12-01

    36 V.33. Coe ncint of De minstioi ........................ 37 V3A. F-Raio .................................... 37 V3.5... de ations. Instructions ae defined as lines of code or card images. Thus, a line containin two or mome souce statements counts as one instruction; a...understand the productivity paradox, recall de concept of virtual machines. When a higher level machine groups ogether many instructm of a lower level

  15. Updated (BP3) Technical and Economic Feasibility Study - Electrochemical Membrane for Carbon Dioxide Capture and Power Generation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ghezel-Ayagh, Hossein

    This topical report summarizes the results of an updated Technical & Economic Feasibility Study (T&EFS) which was conducted in Budget Period 3 of the project to evaluate the performance and cost of the Electrochemical Membrane (ECM)-based CO 2 capture system. The ECM technology is derived from commercially available inorganic membranes; the same used in FuelCell Energy’s commercial fuel cell power plants and sold under the trade name Direct FuelCell® (DFC®). The ECM stacks are utilized in the Combined Electric Power (generation) And Carbon dioxide Separation (CEPACS) systems which can be deployed as add-ons to conventional power plants (Pulverized Coal, Combinedmore » Cycle, etc.) or industrial facilities to simultaneously produce power while capturing >90% of the CO 2 from the flue gas. In this study, an ECM-based CEPACS plant was designed to capture and compress >90% of the CO 2 (for sequestration or beneficial use) from the flue gas of a reference 550 MW (nominal, net AC) Pulverized Coal (PC) Rankine Cycle (Subcritical steam) power plant. ECM performance was updated based on bench scale ECM stack test results. The system process simulations were performed to generate the CEPACS plant performance estimates. The performance assessment included estimation of the parasitic power consumption for CO 2 capture and compression, and the efficiency impact on the PC plant. While the ECM-based CEPACS system for the 550 MW PC plant captures 90% of CO 2 from the flue gas, it generates additional (net AC) power after compensating for the auxiliary power requirements of CO 2 capture and compression. An equipment list, ECM stacks packaging design, and CEPACS plant layout were developed to facilitate the economic analysis. Vendor quotes were also solicited. The economic feasibility study included estimation of CEPACS plant capital cost, cost of electricity (COE) analyses and estimation of cost per ton of CO 2 captured. The incremental COE for the ECM-based CO 2 capture is expected to meet U.S. DOE’s target of 35%. This study has indicated that CEPACS systems offer significant benefits with respect to cost, performance, water consumption and emissions to environment. The realization of these benefits will provide a single solution to carbon dioxide capture in addition to meeting the increasing demand for electricity.« less

  16. Updated (BP3) Technical and Economic Feasibility Study - Electrochemical Membrane for Carbon Dioxide Capture and Power Generation

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Ghezel-Ayagh, Hossein

    This topical report summarizes the results of an updated Technical & Economic Feasibility Study (T&EFS) which was conducted in Budget Period 3 of the project to evaluate the performance and cost of the Electrochemical Membrane (ECM)-based CO2 capture system. The ECM technology is derived from commercially available inorganic membranes; the same used in FuelCell Energy’s commercial fuel cell power plants and sold under the trade name Direct FuelCell® (DFC®). The ECM stacks are utilized in the Combined Electric Power (generation) And Carbon dioxide Separation (CEPACS) systems which can be deployed as add-ons to conventional power plants (Pulverized Coal, Combined Cycle,more » etc.) or industrial facilities to simultaneously produce power while capturing >90% of the CO2 from the flue gas. In this study, an ECM-based CEPACS plant was designed to capture and compress >90% of the CO2 (for sequestration or beneficial use) from the flue gas of a reference 550 MW (nominal, net AC) Pulverized Coal (PC) Rankine Cycle (Subcritical steam) power plant. ECM performance was updated based on bench scale ECM stack test results. The system process simulations were performed to generate the CEPACS plant performance estimates. The performance assessment included estimation of the parasitic power consumption for CO2 capture and compression, and the efficiency impact on the PC plant. While the ECM-based CEPACS system for the 550 MW PC plant captures 90% of CO2 from the flue gas, it generates additional (net AC) power after compensating for the auxiliary power requirements of CO2 capture and compression. An equipment list, ECM stacks packaging design, and CEPACS plant layout were developed to facilitate the economic analysis. Vendor quotes were also solicited. The economic feasibility study included estimation of CEPACS plant capital cost, cost of electricity (COE) analyses and estimation of cost per ton of CO2 captured. The incremental COE for the ECM-based CO2 capture is expected to meet U.S. DOE’s target of 35%. This study has indicated that CEPACS systems offer significant benefits with respect to cost, performance, water consumption and emissions to environment. The realization of these benefits will provide a single solution to carbon dioxide capture in addition to meeting the increasing demand for electricity.« less

  17. Determinants and processes of HIV status disclosure to HIV--infected children aged 4 to 17 years receiving HIV care services at Baylor College of Medicine Children's Foundation Tanzania, Centre of Excellence (COE) in Mbeya: a cross-sectional study.

    PubMed

    Nzota, Mary S; Matovu, Joseph K B; Draper, Heather R; Kisa, Rose; Kiwanuka, Suzanne N

    2015-07-15

    Disclosure of HIV sero-status to HIV-infected children is associated with reduced risk of death and better adherence to antiretroviral drugs. However, caregivers find it difficult to determine when and how they should disclose the HIV sero-positive status to HIV-infected children. In this study, we assessed the determinants and processes of HIV status disclosure to HIV-infected children aged 4 to 17 years receiving HIV care services at the Baylor College of Medicine Children's Foundation Tanzania, Centre of Excellence (COE) in Mbeya. This was a cross-sectional study conducted among 334 caregivers of HIV positive children attending the Baylor COE in Mbeya, Tanzania. Data were collected using quantitative and qualitative research methods. Quantitative data were collected on socio-demographic characteristics of children and caregivers using an interviewer-administered questionnaire. Data were entered into Epi-Info version 3.5.1 and analyzed using STATA version 10. Univariable and multivariable logistic regression analyses were conducted to obtain odds ratios (OR) and 95% confidence intervals (95% CI) associated with disclosing HIV positive status to HIV-infected children. Qualitative data were collected on the processes used in accomplishing the HIV status disclosure event using case histories and key informant interviews and analyzed manually using latent analysis techniques. About one-third of the caregivers (32.6%) disclosed the children's HIV sero-positive status to them. Disclosure was more likely among children 10 years or older (adjusted OR [AOR] = 8.8; 95% CI: 4.7, 16.5), caregivers with knowledge about HIV disclosure (AOR = 5.7; 95% CI: 2.3, 13.7) and those earning more than Tsh 99,999 (US $62.5) per month (AOR = 2.4; 95% CI: 1.3, 4.5). Qualitative findings showed that caregivers used a diversity of approaches to complete the HIV status disclosure event including direct, third-party, event-driven and use of drawings. Our study shows that disclosure is common among older children and is largely driven by the caregivers' knowledge about HIV status disclosure and monthly earnings. HIV status disclosure was accomplished through a variety of approaches. These findings suggest a need to provide caregivers with knowledge about HIV status disclosure approaches to improve HIV status disclosure to HIV-infected children.

  18. Decentralized Algorithms for Optimization of Single Commodity Flows

    DTIC Science & Technology

    1980-06-01

    Offiachstssiue of Navallog Researche o T1 LaoayfrInformation Sytm rgadDcso yt~ NCd SifyiEDN.04-8 Coe47II. CNRLIGOFCAEADADES1. ftoftT ADPIAIO100WORAI Arlington...requirements for the degree of Master of Science at the Massachusetts Institute of Technology, May 1980. The research was conducted at the M.I.T...this thesis topic. His interest and suggestions made the research rewarding. The research was carried out at the M.I.T. Laboratory for Information

  19. A Cultural Resources Reconnaissance of Five Projects in Puerto Rico.

    DTIC Science & Technology

    1980-01-01

    Puerto Rico, Archeology, History, Ethnohistory, Prehistory, COE projects, Rio Puerto Nuevo , Rio Grande de Loiza, Rio Tallaboa, Rio Guanajibo, Rio...results of a 2 week cultural resources reconnaissance of Corps of Engineers projects in Puerto Ricoh Rio Puerto Nuevo , Rio Grande de Loi2a Rio...of Capara a title search of one of the Rio Puerto Nuevo projectO and’informatioI m pson the projects available in the US Army Corps of Engineers San

  20. Proceedings of the U.S. Army Corps of Engineers Surveying Conference Held at Jacksonville, Florida on 4-8 February 1985,

    DTIC Science & Technology

    1985-02-01

    Institute of Technology. He spent many years at Woods Hole, and his primary interests are in the application of signal processing to the problems of...steel caisson island to perform conventional bathymetry surveys, a special system was required. This system which was contructed and used during the...National Ecological Research Areas. o USGS anticipates contacting COE for assistance in updating energy transportation maps, and maps showing port

  1. Recommended Practices in Thrust Measurements

    DTIC Science & Technology

    2013-10-01

    Turin.5,38 This stand consists of two BeCu plates which hang from flexible BeCu mounts on a rigid block of Zerodur c, a material with a very low coe...2013 Figure 4. Example of a state-of-the-art hanging pendulum thrust stand. 38 Two spherical mirrors mounted on the plates form an optical cavity for...the Zerodur frame. Temperature control and careful choice of materials were used to minimize and correct for thermal drift. 2. Thrust Stand Performance

  2. Air Conditioning and Refrigeration. Volume XXVI. 1975 Edition of Course of Study Outlines. Middlesex County Vocational and Technical High Schools and Middlesex County Adult Technical Schools.

    ERIC Educational Resources Information Center

    Capizzi, James

    The two courses of study described and outlined here are offered at Burr D. Coe Vocational and Technical High School in East Brunswick, New Jersey, for students wishing to prepare for a career in air conditioning and refrigeration. Section 1 deals with a 4-year high school course, Section 2 with a 1-year course for those who have completed high…

  3. The Seebeck Coefficient and Phonon Drag in Silicon

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Mahan, Gerald; Lindsay, Lucas R.; Broido, David

    2014-12-29

    We present a theory of the phonon-drag Seebeck coe cient in nondegenerate semiconductors, and apply it to silicon for temperatures 30 < T < 300K. Our calculation uses only parameters from the literature, and previous calculations of the phonon lifetime. We nd excellent agreement with the measurements of Geballe and Hull [Phys.Rev. 98, 940 (1955)]. The phonon-drag term dominates at low temperature, and shows an important dependence on the dimensions of the experimental sample.

  4. The Center of Excellence in High Power Gas Phase Electric and Hybrid Lasers

    DTIC Science & Technology

    2010-10-31

    experimental side, undergraduate Vanessa Salas is working at the COE and is interested in pursuing a PhD in physics. Josh Shapiro is working on data...base quickly and should be able to start collecting data in a few weeks as his experiment is ready to go. Vanessa Salas is working on examining the...CHRISTY ERIC MARTINEZ TANNER OAKES JAKE SMITH KENDRICK WALTER VANESSA SALAS Students from UNM Graduate Student: NATE ZAMEROSKI (PhD

  5. FDTD Modeling and Counteraction to Scintillation Effects in the lonosphere

    DTIC Science & Technology

    2014-04-05

    collection of information if it does not display a currently valid OMB control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. 1. REPORT...for vectorial diffraction calculations and its numerical implementation,” J. Opt. Soc. Am. A, 23 (3), pp. 713-722, 2006. [21] Coe, R. L. and E. J...Seibel, “Improved near-field calculations using vectorial diffraction integrals in the finite-difference time-domain method,” J. Opt. Soc. Am. A, 28

  6. Women in the Army: A Selected Bibliography,

    DTIC Science & Technology

    1982-02-01

    U.S. Naval Postgraduate School , 1976. (V325 U5 Th C38) (Examines the impact that the all-volunteer force, declining number of youths, and political...first woman to attend the field artillery school for officers at Fort Sill, Oklahoma.) *10. Chaze, William. "Academy Women: Ready to Take Command." U.S...experiment in integratior can benefit everyone.) 12. Coe, Gary. "A Cost-Effective Enlistment Supply of Women for the Ar ’ Defense Management Journal, Vol. 15

  7. Methodology for Prioritization of Investments to Support the Army Energy Strategy for Installations

    DTIC Science & Technology

    2012-07-01

    kind of energy source onto its own footprint. Whether this is a solar, wind, biomass, geothermal , or any other kind of renewable energy source, it...more common. Right now extortion and disgruntled employers are the attacked and not sophisticated enemies such as China . Our current nation power...users to: • Estimate the NPV cost of energy (COE) and levelized cost of energy (LCOE) from a range of solar, wind and geothermal electricity generation

  8. Reclamation of abandoned mined lands along th Upper Illinois Waterway using dredged material

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Van Luik, A; Harrison, W

    1982-01-01

    Sediments were sampled and characterized from 28 actual or proposed maintenance-dredging locations in the Upper Illinois Waterway, that is, the Calumet-Sag Channel, the Des Plaines River downstream of its confluence with the Calumet-Sag Channel, and the Illinois River from the confluence of the Kankakee and Des Plaines rivers to Havana, Illinois. Sufficient data on chemical constituents and physical sediments were obtained to allow the classification of these sediments by currently applicable criteria of the Illinois Environmental Protection Agency for the identification of hazardous, persistent, and potentially hazardous wastes. By these criteria, the potential dredged materials studied were not hazardous, persistent,more » or potentially hazardous; they are a suitable topsoil/ reclamation medium. A study of problem abandoned surface-mined land sites (problem lands are defined as being acidic and/or sparsely vegetated) along the Illinois River showed that three sites were particularly well suited to the needs of the Corps of Engineers (COE) for a dredged material disposal/reclamation site. Thes sites were a pair of municipally owned sites in Morris, Illinois, and a small corporately owned site east of Ottawa, Illinois, and adjacent to the Illinois River. Other sites were also ranked as to suitability for COE involvement in their reclamation. Reclamation disposal was found to be an economically competitive alternative to near-source confined disposal for Upper Illinois Waterway dredged material.« less

  9. Age-related differences in reliance behavior attributable to costs within a human-decision aid system.

    PubMed

    Ezer, Neta; Fisk, Arthur D; Rogers, Wendy A

    2008-12-01

    An empirical investigation was done to determine if there are age-related differences attributable to costs in reliance on a decision aid. Costs of reliance on a decision aid may affect reliance on the aid. Older and younger adults may not perceive and respond to a dynamic cost structure equally or objectively. Sixteen older adults (65-74 years) and 16 younger adults (18-28 years) performed a counting task with an imperfect decision aid. Two types of costs were manipulated: (a) cost of error (CoE) and (b) cost of verification (CoV). The percentage of trials in which participants agreed with the decision aid and did not perform the task manually was recorded as reliance. Participants decreased their reliance as the CoE increased and increased their reliance with a lower CoV; however, they tended to underrely on the decision aid. Younger adults tended to change their reliance behavior more than older adults did with the changing cost structure. Older and younger adults appear to interpret costs differently, with older adults being less responsive to changes in costs. Older adults may have been less able to monitor the changing costs and hence not adapt to them as well as younger adults. Designers of decision aids should consider explicitly stating costs associated with reliance on the aid, as individuals may differ in how they interpret and respond to changing costs.

  10. Probiotics and the Microbiome in Celiac Disease: A Randomised Controlled Trial

    PubMed Central

    Myers, Stephen P.; Rolfe, Margaret

    2016-01-01

    Background. There is limited research investigating the composition of the gastrointestinal microbiota in individuals with celiac disease (CoeD) reporting only partial symptom improvement despite adherence to a strict gluten-free diet (GFD). The aim of this research was to determine if the gastrointestinal microbiota could be altered by probiotic bacteria and provide a potential new therapy for this subgroup. Methods. A multicentre RCT was conducted between January and August 2011 in Australia. Participants included 45 people with CoeD reporting only partial symptom improvement despite adherence to a strict GFD for a minimum of 12 months. Participants took 5 g of VSL#™ probiotic formulation (n = 23) or 5 g placebo (n = 22) orally twice daily for 12 weeks. The main outcome measured was the efficacy of the probiotic formula in altering faecal microbiota counts between baseline and week 12. Safety was determined by safety blood and monitoring adverse events. Results. SPSS™ multivariate repeated measures analysis (95th confidence level) revealed no statistically significant changes between the groups in the faecal microbiota counts or blood safety measures over the course of the study. Conclusion. The probiotic formula when taken orally over the 12-week period did not significantly alter the microbiota measured in this population. The trial was registered with Australian and New Zealand Clinical Trials Register ACTRN12610000630011. PMID:27525027

  11. An Assessment of Three Different In Situ Oxygen Sensors for Monitoring Silage Production and Storage.

    PubMed

    Shan, Guilin; Sun, Yurui; Li, Menghua; Jungbluth, Kerstin H; Maack, Christian; Buescher, Wolfgang; Schütt, Kai-Benjamin; Boeker, Peter; Lammers, Peter Schulze; Zhou, Haiyang; Cheng, Qiang; Ma, Daokun

    2016-01-14

    Oxygen (O₂) concentration inside the substrate is an important measurement for silage-research and-practical management. In the laboratory gas chromatography is commonly employed for O₂ measurement. Among sensor-based techniques, accurate and reliable in situ measurement is rare because of high levels of carbon dioxide (CO₂) generated by the introduction of O₂ in the silage. The presented study focused on assessing three types of commercial O₂ sensors, including Clark oxygen electrodes (COE), galvanic oxygen cell (GOC) sensors and the Dräger chip measurement system (DCMS). Laboratory cross calibration of O₂ versus CO₂ (each 0-15 vol.%) was made for the COE and the GOC sensors. All calibration results verified that O₂ measurements for both sensors were insensitive to CO₂. For the O₂ in situ measurement in silage, all O₂ sensors were first tested in two sealed barrels (diameter 35.7 cm; height: 60 cm) to monitor the O₂ depletion with respect to the ensiling process (Test-A). The second test (Test-B) simulated the silage unloading process by recording the O₂ penetration dynamics in three additional barrels, two covered by dry ice (0.6 kg or 1.2 kg of each) on the top surface and one without. Based on a general comparison of the experimental data, we conclude that each of these in situ sensor monitoring techniques for O₂ concentration in silage exhibit individual advantages and limitations.

  12. Applications of the Sensor Fish Technology

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Deng, Zhiqun; Carlson, Thomas J.; Duncan, Joanne P.

    2007-08-28

    The Sensor Fish is an autonomous device developed at Pacific Northwest National Laboratory for U.S. Department of Energy (DOE) and Army Corps of Engineers (COE) to better understand the physical conditions fish experience during passage through hydro-turbines and other dam bypass alternatives. Since its initial development in 1997, the Sensor Fish has undergone several design changes to improve its function and extend the range of its use. The most recent Sensor Fish design, the six-degree-of-freedom (6DOF) device, has been deployed successfully to characterize the environment fish experience when they pass through several hydroelectric projects along main stem Columbia and Snakemore » Rivers in the Pacific Northwest. Just as information gathered from crash test dummies can affect automobile design with the installation of protective designs to lessen or prevent human injury, having sensor fish data to quantify accelerations, rotations, and pressure changes, helps identify fish injury mechanisms such as strike, turbulent shear, pressure, and inertial effects, including non-lethal ones such as stunning or signs of vestibular disruption that expose fish to a higher risk of predation by birds and piscivorous fish downstream following passage.« less

  13. C-band radar observes water level change in swamp forests

    USGS Publications Warehouse

    Lu, Zhong; Crane, Mike; Kwoun, Oh-Ig; Wells, Christopher J.; Rykhus, Russ

    2005-01-01

    Wetlands cover more than 4% of the Earth's land surface and interact with hydrologic, biogeochemical, and sediment transport processes that are fundamental in understanding ecological and climatic changes [Alsdorf et al, 2003; Prigent et al., 2001 ; Melack and Forsberg, 2000;Dunne et al., 1998]. Measurement of water level changes in wetlands, and consequently of changes in water storage capacity, provides a required input for hydrologic models, and is required to comprehensively assess flood hazards [e.g., Coe, 1998].

  14. 16-Inch Gun-Launched Anti-Satellite Weapon

    DTIC Science & Technology

    1982-06-01

    Boulevard Arlington, va 22209 2 06.82 09 1 6 004, NAVAL POSTGRADUATE SCHOOL Monterey, California Rear Admiral J. J. Ekelund David Schrady...Monterey, California 93940 92 IS. M ON IWO *GMC’V MNAM 6 A---SMI dxlfma ftgI CoeMIM Offee) 1 . S6CMURInV CLASS. tog Woa F .ON) Defense Advanced Research...distribution unlimited D? ISNIOUFI@N STATEMENIT M .ue d 4008004H #A DIVIN 20. It AEfftmmU OW ROOMat) .4 1 . SUPLEMo.$Eim[NANY tMOVWS Gun-Launched, ASAT

  15. A Physics-Based Heterojunction Bipolar Transistor Model for Integrated Circuit Simulation

    DTIC Science & Technology

    1993-12-01

    Laverghetta, Practical Microwaves, IN, Howard W. Sams & Co., 1984. [56] C. R . Selvakumar , "A New Minority Carrier Lifetime Model for Heavily Doped GaAs...transistor common-emitter output conductance (S). gm Small-signal transconductance (S). r Reflection coefficient of a transmission line. ’Y Emitter...material and geometry parameters to equivalent circuit element values. Typically, the first step in 6 C RC Re + VWc- +B B ,a W’ COE ’IIc I R E Figure 1.7

  16. The Coast Artillery Journal. Volume 71, Number 1, July 1929

    DTIC Science & Technology

    1929-07-01

    the answer in a study of the behaviour of insects and spiders. Major Hingston has spent many years in collecting data and in the end he concludes that...H ere’s to the R. A . R., by gosh, and its little- n F. W. COE, . Major General, Chief of Coast Artillery. HEADQUARTERS RAILWAY ARTILLERY RESERVE...same, and to keep the Army Artillery commander advised thereof. (c) To maintain a continuing study of the possibilities for the use of Railway Artillery

  17. High Angular Resolution Microwave Sensing with Large, Sparse, Random Arrays.

    DTIC Science & Technology

    1982-12-01

    corner reflectors that setdf the requirements de - To satsf the first condition the radar ros section of the scie above. adpiebeamformer must exceed the...eTetv patc weeveidth& oh Combninwhee xpressian’ons adst Ta rhecneiremea- To confine the mepne of the filter to echoes from the de - upon beacon power: ired...the mean2 sq weeho srength of the scatterers. Thus, the de control olaefor the Phone shifter is proportional to coe*0. Since the SUMMARY loop drive this

  18. Comprehensive Reproductive System Care Program - Clinical Breast Care Project (CRSCP-CBCP)

    DTIC Science & Technology

    2011-03-01

    or breast surgery at WRAMC, WMC, AAMC, and our affiliated hospitals, who consent to participate in BC-COE IRB- approved protocols. • Collect and...collect data on all female patients 18 and older who present to the General Surgery Clinic at Walter Reed Army Medical Center and are found to be at an...edge breast center. They have added 4 additional exam rooms, a bariatric exam room with a two procedure rooms, a counselor’s office, conference room

  19. Environmental Impact Statement/Environmental Impact Report for the Disposal and Reuse of Mare Island Naval Shipyard Vallejo, California. Volume 1.

    DTIC Science & Technology

    1998-04-01

    Valley (Kroeber & Heizer 1970). In 1972, the Bureau of Indian Affairs listed only 11 individuals claiming Patwin ancestry in the entire territory...facility from the dredge disposal area to the upland open space scenic resource area would render this facility visible from viewpoints with . high...take. The COE probably would not issue a permit unless the USFWS rendered a "non-jeopardy" Biological Opinion, which would incorporate mitigations for

  20. Minutes of the Explosives Safety Seminar (25th) Held in Anaheim, California on 18-20 August 1992. Volume 3

    DTIC Science & Technology

    1992-08-20

    the potential health and safety effects posed by the hazardous waste and ordnance at the site. When the COE began our studies, the media began to...all with the contamination can still be affected through the food chain. This is not true for OEW. The population at risk is effectively limited to...a serious health hazard. The effects of ordnance and explosive waste exposures are much more immediate, and easier to measure. Most of the time

  1. Intelligent Multi-Media Integrated Interface Project

    DTIC Science & Technology

    1990-06-01

    RADC (COES) Griffiss AFB NY 13441-5700. This will assist us in main- taining a current mailing list. Do not return copies of this report unless...contractual obligations or notices on a specific document require that it be returned. INTELLIGENT MULTI-MEDIA INTEGRATED INTERFACE PROJECT J. G. Neal J. M...lure ag. A = W qMN 1. AGENCY USE ONLY AM BW 2. REPORT DATE R,,PE AND DATES COYERED June 1990 Final Oct 87 to Oct 89 4. TTLE AND SUIlllLE S. FUNDING

  2. Applying design principles to fusion reactor configurations for propulsion in space

    NASA Technical Reports Server (NTRS)

    Carpenter, Scott A.; Deveny, Marc E.; Schulze, Norman R.

    1993-01-01

    The application of fusion power to space propulsion requires rethinking the engineering-design solution to controlled-fusion energy. Whereas the unit cost of electricity (COE) drives the engineering-design solution for utility-based fusion reactor configurations; initial mass to low earth orbit (IMLEO), specific jet power (kW(thrust)/kg(engine)), and reusability drive the engineering-design solution for successful application of fusion power to space propulsion. We applied three design principles (DP's) to adapt and optimize three candidate-terrestrial-fusion-reactor configurations for propulsion in space. The three design principles are: provide maximum direct access to space for waste radiation, operate components as passive radiators to minimize cooling-system mass, and optimize the plasma fuel, fuel mix, and temperature for best specific jet power. The three candidate terrestrial fusion reactor configurations are: the thermal barrier tandem mirror (TBTM), field reversed mirror (FRM), and levitated dipole field (LDF). The resulting three candidate space fusion propulsion systems have their IMLEO minimized and their specific jet power and reusability maximized. We performed a preliminary rating of these configurations and concluded that the leading engineering-design solution to space fusion propulsion is a modified TBTM that we call the Mirror Fusion Propulsion System (MFPS).

  3. Software IV and V Research Priorities and Applied Program Accomplishments Within NASA

    NASA Technical Reports Server (NTRS)

    Blazy, Louis J.

    2000-01-01

    The mission of this research is to be world-class creators and facilitators of innovative, intelligent, high performance, reliable information technologies that enable NASA missions to (1) increase software safety and quality through error avoidance, early detection and resolution of errors, by utilizing and applying empirically based software engineering best practices; (2) ensure customer software risks are identified and/or that requirements are met and/or exceeded; (3) research, develop, apply, verify, and publish software technologies for competitive advantage and the advancement of science; and (4) facilitate the transfer of science and engineering data, methods, and practices to NASA, educational institutions, state agencies, and commercial organizations. The goals are to become a national Center Of Excellence (COE) in software and system independent verification and validation, and to become an international leading force in the field of software engineering for improving the safety, quality, reliability, and cost performance of software systems. This project addresses the following problems: Ensure safety of NASA missions, ensure requirements are met, minimize programmatic and technological risks of software development and operations, improve software quality, reduce costs and time to delivery, and improve the science of software engineering

  4. Gearbox Reliability Collaborative Phase 3 Gearbox 2 Test Plan

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Link, H.; Keller, J.; Guo, Y.

    2013-04-01

    Gearboxes in wind turbines have not been achieving their expected design life even though they commonly meet or exceed the design criteria specified in current design standards. One of the basic premises of the National Renewable Energy Laboratory (NREL) Gearbox Reliability Collaborative (GRC) is that the low gearbox reliability results from the absence of critical elements in the design process or insufficient design tools. Key goals of the GRC are to improve design approaches and analysis tools and to recommend practices and test methods resulting in improved design standards for wind turbine gearboxes that lower the cost of energy (COE)more » through improved reliability. The GRC uses a combined gearbox testing, modeling and analysis approach, along with a database of information from gearbox failures collected from overhauls and investigation of gearbox condition monitoring techniques to improve wind turbine operations and maintenance practices. Testing of Gearbox 2 (GB2) using the two-speed turbine controller that has been used in prior testing. This test series will investigate non-torque loads, high-speed shaft misalignment, and reproduction of field conditions in the dynamometer. This test series will also include vibration testing using an eddy-current brake on the gearbox's high speed shaft.« less

  5. Uncovering the Minor Contribution of Land-Cover Change in Upland Forests to the Net Carbon Footprint of a Boreal Hydroelectric Reservoir.

    PubMed

    Dessureault, Pierre-Luc; Boucher, Jean-François; Tremblay, Pascal; Bouchard, Sylvie; Villeneuve, Claude

    2015-07-01

    Hydropower in boreal conditions is generally considered the energy source emitting the least greenhouse gas per kilowatt-hour during its life cycle. The purpose of this study was to assess the relative contribution of the land-use change on the modification of the carbon sinks and sources following the flooding of upland forested territories to create the Eastmain-1 hydroelectric reservoir in Quebec's boreal forest using Carbon Budget Model of the Canadian Forest Sector. Results suggest a carbon sink loss after 100 yr of 300,000 ± 100,000 Mg CO equivalents (COe). A wildfire sensitivity analysis revealed that the ecosystem would have acted as a carbon sink as long as <75% of the territory had burned over the 100-yr-long period. Our long-term net carbon flux estimate resulted in emissions of 4 ± 2 g COe kWh as a contribution to the carbon footprint calculation, one-eighth what was obtained in a recent study that used less precise and less sensitive estimates. Consequently, this study significantly reduces the reported net carbon footprint of this reservoir and reveals how negligible the relative contribution of the land-use change in upland forests to the total net carbon footprint of a hydroelectric reservoir in the boreal zone can be. Copyright © by the American Society of Agronomy, Crop Science Society of America, and Soil Science Society of America, Inc.

  6. Low Wind Speed Turbine Project Phase II: The Application of Medium-Voltage Electrical Apparatus to the Class of Variable Speed Multi-Megawatt Low Wind Speed Turbines; 15 June 2004--30 April 2005

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Erdman, W.; Behnke, M.

    2005-11-01

    Kilowatt ratings of modern wind turbines have progressed rapidly from 50 kW to 1,800 kW over the past 25 years, with 3.0- to 7.5-MW turbines expected in the next 5 years. The premise of this study is simple: The rapid growth of wind turbine power ratings and the corresponding growth in turbine electrical generation systems and associated controls are quickly making low-voltage (LV) electrical design approaches cost-ineffective. This report provides design detail and compares the cost of energy (COE) between commercial LV-class wind power machines and emerging medium-voltage (MV)-class multi-megawatt wind technology. The key finding is that a 2.5% reductionmore » in the COE can be achieved by moving from LV to MV systems. This is a conservative estimate, with a 3% to 3.5% reduction believed to be attainable once purchase orders to support a 250-turbine/year production level are placed. This evaluation considers capital costs as well as installation, maintenance, and training requirements for wind turbine maintenance personnel. Subsystems investigated include the generator, pendant cables, variable-speed converter, and padmount transformer with switchgear. Both current-source and voltage-source converter/inverter MV topologies are compared against their low-voltage, voltage-source counterparts at the 3.0-, 5.0-, and 7.5-MW levels.« less

  7. An Assessment of Three Different In Situ Oxygen Sensors for Monitoring Silage Production and Storage

    PubMed Central

    Shan, Guilin; Sun, Yurui; Li, Menghua; Jungbluth, Kerstin H.; Maack, Christian; Buescher, Wolfgang; Schütt, Kai-Benjamin; Boeker, Peter; Schulze Lammers, Peter; Zhou, Haiyang; Cheng, Qiang; Ma, Daokun

    2016-01-01

    Oxygen (O2) concentration inside the substrate is an important measurement for silage-research and-practical management. In the laboratory gas chromatography is commonly employed for O2 measurement. Among sensor-based techniques, accurate and reliable in situ measurement is rare because of high levels of carbon dioxide (CO2) generated by the introduction of O2 in the silage. The presented study focused on assessing three types of commercial O2 sensors, including Clark oxygen electrodes (COE), galvanic oxygen cell (GOC) sensors and the Dräger chip measurement system (DCMS). Laboratory cross calibration of O2 versus CO2 (each 0–15 vol.%) was made for the COE and the GOC sensors. All calibration results verified that O2 measurements for both sensors were insensitive to CO2. For the O2 in situ measurement in silage, all O2 sensors were first tested in two sealed barrels (diameter 35.7 cm; height: 60 cm) to monitor the O2 depletion with respect to the ensiling process (Test-A). The second test (Test-B) simulated the silage unloading process by recording the O2 penetration dynamics in three additional barrels, two covered by dry ice (0.6 kg or 1.2 kg of each) on the top surface and one without. Based on a general comparison of the experimental data, we conclude that each of these in situ sensor monitoring techniques for O2 concentration in silage exhibit individual advantages and limitations. PMID:26784194

  8. Cretin Memory Flow on Sierra

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Langer, S. H.; Scott, H. A.

    2016-08-05

    The Cretin iCOE project has a goal of enabling the efficient generation of Non-LTE opacities for use in radiation-hydrodynamic simulation codes using the Nvidia boards on LLNL’s upcoming Sierra system. Achieving the desired level of accuracy for some simulations require the use of a vary large number of atomic configurations (a configuration includes the atomic level for all electrons and how they are coupled together). The NLTE rate matrix needs to be solved separately in each zone. Calculating NLTE opacities can consume more time than all other physics packages used in a simulation.

  9. The Lilongwe Central Hospital Patient Management Information System: A Success in Computer-Based Order Entry Where One Might Least Expect It

    PubMed Central

    GP, Douglas; RA, Deula; SE, Connor

    2003-01-01

    Computer-based order entry is a powerful tool for enhancing patient care. A pilot project in the pediatric department of the Lilongwe Central Hospital (LCH) in Malawi, Africa has demonstrated that computer-based order entry (COE): 1) can be successfully deployed and adopted in resource-poor settings, 2) can be built, deployed and sustained at relatively low cost and with local resources, and 3) has a greater potential to improve patient care in developing than in developed countries. PMID:14728338

  10. Environmental Analysis of the Upper Susitna River Basin using Landsat Imagery

    DTIC Science & Technology

    1980-01-01

    CourseslData Measuring Sites (SCS) 0 Snow Cover Measurement Location 4 C R RE /N OAA) j HŔ River Gauging Station (UISGS, COE) tI’ql with Water...large-scale map that can be used in selection of moved westward across the area (Kachadoorian drilling sites, provide a basis for estimating 1974...A033500 petrology and structure of the Maclaren, Ruby Range McKim, H L, L W Gatto, C I Merry, and R K Haugen (1976b) and Coast Range Belts implications

  11. Using Commercial Practices in DoD Acquisition: A Page from Industry’s Playbook

    DTIC Science & Technology

    1989-12-01

    IMPLfTLO COUTRACT FORM ADAPrED SSCEDLE E• MAPS - P4 ESUPClS TO "OLD .SCHeOUL QUICK RE[SPO • TO FIELD F .XPtPW FNCE /TORY•FO MA C _GREATLY _ _•O...hyrqieacmrhniemngmndemL) This epureation the gates ineor d paca - system to integrate the efforts uf many people,dem ic exposure to the latest in...line. The -- With extremely tight temperature and ;•c.1’ U~.Coe’ required much higher performanc,, humidity control, compressed air and special pro

  12. Simulation of the Dropping Mercury Electrode by Orthogonal Collocation.

    DTIC Science & Technology

    1982-08-18

    Electro byOtoyI =111. - e 15,, "A’Al,.rt arp t2g? ____________ ;f f-1e of Navel Rehnar..h .905 Chemistry Program - Chemitry CO&e 41? Unkclass ified Pe . nI...transport to a dropping mercury electrode lomr.i. Accurate values for’ the concentration profiles and current are obtained with minimal computational effort...offered by COMPUTATIONAL ASP’ECTS KOutecky (14) which is corrected for spherical dittusion Results accurate to 0.4 0 of Koutecky’s calculated values I 08 n

  13. A Three-Dimensional Transonic, Potential Flow Computer Program, Its Conversion to IBM Fortran and Utilization

    DTIC Science & Technology

    1983-12-01

    MAIN OEG=NFGVB1.3266P //COPY PEOC EILE=, MEM = // EXEC PGM=IEBGENEB //SISPRINT DD SYSOUT=A //SYSIN DC DÖMMY //SYS0T1 DD...COE*,FILE=1, MEM =FL027 // EXEC COPY,FILE=2,HEM=A411IN // EXEC COEY,FILE=3, MEM =VWIN // EXEC COPY,FILE = 4, MEM =A411A01...EXEC C0EY,FILE=5,MEä=INTERE // EXEC COPY,FILE=6, MEM =A411PS // EXEC COEY,FILE=7, MEM =A411P1 // EXEC COPY,FILE

  14. Effect of ZrO2 Source Variations on PbZrO3 - PbTiO3 Piezoelectric Properties.

    DTIC Science & Technology

    1980-01-15

    wfatevalatediohryand wetbnde led/1cn Dipatont aod blNdigohvrywssontoyedP- aeilwt Coe 71 Wsingtongq D roC., e 20390 dnit Z-T ID 5,RM 1473 EDITION OF CAIO NOVGADN...PZ-PT 19 D . Coprecipitation of PZ-PT 26 IV SUMMARY AND CONCLUSIONS 33 V ACKNOWLEDGEMENTS 34 46 0 I 347602V ! _ _ A List of Illustrations Figure Page 1...chloride solution may be processed further to give high-purity zirconium (or zirconyl) compounds, such as the oxide, fluoride, nitrate , sulfate and

  15. Final Technical Report Power through Policy: "Best Practices" for Cost-Effective Distributed Wind

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Rhoads-Weaver, Heather; Gagne, Matthew; Sahl, Kurt

    2012-02-28

    Power through Policy: 'Best Practices' for Cost-Effective Distributed Wind is a U.S. Department of Energy (DOE)-funded project to identify distributed wind technology policy best practices and to help policymakers, utilities, advocates, and consumers examine their effectiveness using a pro forma model. Incorporating a customized feed from the Database of State Incentives for Renewables and Efficiency (DSIRE), the Web-based Distributed Wind Policy Comparison Tool (Policy Tool) is designed to assist state, local, and utility officials in understanding the financial impacts of different policy options to help reduce the cost of distributed wind technologies. The project's final products include the Distributed Windmore » Policy Comparison Tool, found at www.windpolicytool.org, and its accompanying documentation: Distributed Wind Policy Comparison Tool Guidebook: User Instructions, Assumptions, and Case Studies. With only two initial user inputs required, the Policy Tool allows users to adjust and test a wide range of policy-related variables through a user-friendly dashboard interface with slider bars. The Policy Tool is populated with a variety of financial variables, including turbine costs, electricity rates, policies, and financial incentives; economic variables including discount and escalation rates; as well as technical variables that impact electricity production, such as turbine power curves and wind speed. The Policy Tool allows users to change many of the variables, including the policies, to gauge the expected impacts that various policy combinations could have on the cost of energy (COE), net present value (NPV), internal rate of return (IRR), and the simple payback of distributed wind projects ranging in size from 2.4 kilowatts (kW) to 100 kW. The project conducted case studies to demonstrate how the Policy Tool can provide insights into 'what if' scenarios and also allow the current status of incentives to be examined or defended when necessary. The ranking of distributed wind state policy and economic environments summarized in the attached report, based on the Policy Tool's default COE results, highlights favorable market opportunities for distributed wind growth as well as market conditions ripe for improvement. Best practices for distributed wind state policies are identified through an evaluation of their effect on improving the bottom line of project investments. The case studies and state rankings were based on incentives, power curves, and turbine pricing as of 2010, and may not match the current results from the Policy Tool. The Policy Tool can be used to evaluate the ways that a variety of federal and state policies and incentives impact the economics of distributed wind (and subsequently its expected market growth). It also allows policymakers to determine the impact of policy options, addressing market challenges identified in the U.S. DOE's '20% Wind Energy by 2030' report and helping to meet COE targets. In providing a simple and easy-to-use policy comparison tool that estimates financial performance, the Policy Tool and guidebook are expected to enhance market expansion by the small wind industry by increasing and refining the understanding of distributed wind costs, policy best practices, and key market opportunities in all 50 states. This comprehensive overview and customized software to quickly calculate and compare policy scenarios represent a fundamental step in allowing policymakers to see how their decisions impact the bottom line for distributed wind consumers, while estimating the relative advantages of different options available in their policy toolboxes. Interested stakeholders have suggested numerous ways to enhance and expand the initial effort to develop an even more user-friendly Policy Tool and guidebook, including the enhancement and expansion of the current tool, and conducting further analysis. The report and the project's Guidebook include further details on possible next steps. NREL Report No. BK-5500-53127; DOE/GO-102011-3453.« less

  16. Molecular characterization of the spike gene of the porcine epidemic diarrhea virus in Mexico, 2013-2016.

    PubMed

    Lara-Romero, Rocío; Gómez-Núñez, Luis; Cerriteño-Sánchez, José Luis; Márquez-Valdelamar, Laura; Mendoza-Elvira, Susana; Ramírez-Mendoza, Humberto; Rivera-Benítez, José Francisco

    2018-04-01

    In Mexico, the first outbreaks suggestive of the circulation of the porcine epidemic diarrhea virus (PEDV) were identified at the beginning of July 2013. To identify the molecular characteristics of the PEDV Spike (S) gene in Mexico, 116 samples of the intestine and diarrhea of piglets with clinical signs of porcine epidemic diarrhea (PED) were obtained. Samples were collected from 14 farms located in six states of Mexico (Jalisco, Puebla, Sonora, Veracruz, Guanajuato, and Michoacán) from 2013 to 2016. To identify PEDV, we used real-time RT-PCR to discriminate between non-INDEL and INDEL strains. We chose samples according to state and year to characterize the S gene. After amplification of the S gene, the obtained products were sequenced and assembled. The complete amino acid sequences of the spike protein were used to perform an epitope analysis, which was used to determine null mutations in regions SS2, SS6, and 2C10 compared to the sequences of G2. A phylogenetic analysis determined the circulation of G2b and INDEL strains in Mexico. However, several mutations were recorded in the collagenase equivalent (COE) region that were related to the change in polarity and charge of the amino acid residues. The PEDV strain circulating in Jalisco in 2016 has an insertion of three amino acids ( 232 LGL 234 ) and one change in the antigenic site of the COE region, and strains from the years 2015 and 2016 changed the index of the surface probability, which could be related to the re-emergence of disease outbreaks.

  17. Wind Generator & Biomass No-draft Gasification Hybrid

    NASA Astrophysics Data System (ADS)

    Hein, Matthew R.

    The premise of this research is that underutilized but vast intermittent renewable energy resources, such as wind, can become more market competitive by coupling with storable renewable energy sources, like biomass; thereby creating a firm capacity resource. Specifically, the Midwest state of South Dakota has immense wind energy potential that is not used because of economic and logistic barriers of electrical transmission or storage. Coupling the state's intermittent wind resource with another of the state's energy resources, cellulosic non-food biomass, by using a wind generator and no-draft biomass gasification hybrid system will result in a energy source that is both firm and storable. The average energy content of common biomass feedstock was determined, 14.8 MJ/kg (7.153 Btu/lb), along with the assumed typical biomass conversion efficiency of the no-draft gasifier, 65%, so that an average electrical energy round trip efficiency (RTE) of 214% can be expected (i.e. One unit of wind electrical energy can produce 2.14 kWh of electrical energy stored as syngas.) from a wind generator and no-draft biomass gasification system. Wind characteristics are site specific so this analysis utilizes a synthetic wind resource to represent a statistically sound gross representation of South Dakota's wind regime based on data from the Wind Resource Assessment Network (WRAN) locations. A synthetic wind turbine generated from common wind turbine power curves and scaled to 1-MW rated capacity was utilized for this analysis in order to remove equipment bias from the results. A standard 8,760-hour BIN Analysis model was constructed within HOMER, powerful simulation software developed by the National Renewable Energy Laboratory (NREL) to model the performance of renewable power systems. It was found that the optimum configuration on a per-megawatt-transmitted basis required a wind generator (wind farm) rated capacity of 3-MW with an anticipated annual biomass feedstock of 26,132 GJ or an anticipated 1,766 tonnes of biomass. The levelized cost of electricity (COE) ranged from 65.6/GJ (236/MWh) to 208.9/GJ (752/MWh) with the price of generated electricity being most sensitive to the biomass feedstock cost and the levelized COE being significantly impacted by the high cost of compressed storage. The resulting electrical energy available to the grid has an approximate wholesale value of 13.5/GJ (48.6/MWh) based on year 2007 Midwest Reliability Organization (MRO) regional averages [1]. Therefore, the annual average wholesale value of the generated electricity is lower than the cost to produce the electricity. A significant deficiency of this simple comparison is that it does not consider the fact that the proposed wind and biomass gasification hybrid is now a dispatchable source of electricity with a near net-zero lifetime carbon footprint and storage capability. Dispatchable power can profit from market fluctuations that dramatically increase the value of available electricity so that in addition to providing base power the hybrid facility can store energy during low price points in the market and generate at full capacity during points of high prices. Any financial incentive for energy generated from reduced carbon technologies will also increase the value of electricity produced. Also, alternative operational parameters that do not require the costly storage of synthetic natural gas (SNG) will likely result in a more competitive levelized COE. Additional benefits of the system are in the flexibility of transporting wind and biomass energy produced as well as the end use of the energy. Instead of high-voltage electrical transmission a gas line can now be used to transport energy produced by the wind. Syngas can also be further processed into higher energy density liquefied syngas. Liquid fuels can then be transported via commercial freight on existing road infrastructure.

  18. Common object request broker architecture (CORBA)-based security services for the virtual radiology environment.

    PubMed

    Martinez, R; Cole, C; Rozenblit, J; Cook, J F; Chacko, A K

    2000-05-01

    The US Army Great Plains Regional Medical Command (GPRMC) has a requirement to conform to Department of Defense (DoD) and Army security policies for the Virtual Radiology Environment (VRE) Project. Within the DoD, security policy is defined as the set of laws, rules, and practices that regulate how an organization manages, protects, and distributes sensitive information. Security policy in the DoD is described by the Trusted Computer System Evaluation Criteria (TCSEC), Army Regulation (AR) 380-19, Defense Information Infrastructure Common Operating Environment (DII COE), Military Health Services System Automated Information Systems Security Policy Manual, and National Computer Security Center-TG-005, "Trusted Network Interpretation." These documents were used to develop a security policy that defines information protection requirements that are made with respect to those laws, rules, and practices that are required to protect the information stored and processed in the VRE Project. The goal of the security policy is to provide for a C2-level of information protection while also satisfying the functional needs of the GPRMC's user community. This report summarizes the security policy for the VRE and defines the CORBA security services that satisfy the policy. In the VRE, the information to be protected is embedded into three major information components: (1) Patient information consists of Digital Imaging and Communications in Medicine (DICOM)-formatted fields. The patient information resides in the digital imaging network picture archiving and communication system (DIN-PACS) networks in the database archive systems and includes (a) patient demographics; (b) patient images from x-ray, computed tomography (CT), magnetic resonance imaging (MRI), and ultrasound (US); and (c) prior patient images and related patient history. (2) Meta-Manager information to be protected consists of several data objects. This information is distributed to the Meta-Manager nodes and includes (a) radiologist schedules; (b) modality worklists; (c) routed case information; (d) DIN-PACS and Composite Health Care system (CHCS) messages, and Meta-Manager administrative and security information; and (e) patient case information. (3) Access control and communications security is required in the VRE to control who uses the VRE and Meta-Manager facilities and to secure the messages between VRE components. The CORBA Security Service Specification version 1.5 is designed to allow up to TCSEC's B2-level security for distributed objects. The CORBA Security Service Specification defines the functionality of several security features: identification and authentication, authorization and access control, security auditing, communication security, nonrepudiation, and security administration. This report describes the enhanced security features for the VRE and their implementation using commercial CORBA Security Service software products.

  19. Patoka Lake Foundation Report. Book 4. Appendix D. Contractor Drill Logs.

    DTIC Science & Technology

    1983-04-01

    IJK1 f°- ..... . .0 e". a I’e ~ .1 , 34.. 411 go-- t.__ 4p//, /, -.z fr FNC PORN 1836 PREVIOUS EDITIONS ARE OBSOLETE PROJECT HOLE NO. MAR71 t...AE OSOLTS. PROECT 4OL NO BEEI 71 /A*I .. ~ ~ ISO LOCATIONIO (C.U4.i. N, TII~ .3____________________________ 1. -ROJET IA. siOTAND NTMPER orE BOi E S...IN ~ .. d N.1 K. SGAUEOINPO. R I.*.R. f.4~k . T Od OF HOLELVTO LEGEN ", UIIC , CL •% COE ,p JNP LIt ./" /yIf/ -z- 8MNG PORN # 18 36 PREVIOUS EDI

  20. M≡E and M=E Complexes of Iron and Cobalt that Emphasize Three-fold Symmetry (E = O, N, NR)

    PubMed Central

    Saouma, Caroline T.; Peters, Jonas C.

    2011-01-01

    Mid-to-late transition metal complexes that feature terminal, multiply bonded ligands such as oxos, imides, and nitrides have been invoked as intermediates in several catalytic transformations of synthetic and biological significance. Until about ten years ago, isolable examples of such species were virtually unknown. Over the past decade or so, numerous chemically well-defined examples of such species have been discovered. In this context, the presentreview summarizes the development of 4- and 5-coordinate Fe(E) and Co(E) species under local three-fold symmetry. PMID:21625302

  1. RECOVERY, A Mathematical Model to Predict the Temporal Response of Surface Water to Contaminated Sediments.

    DTIC Science & Technology

    1994-11-01

    NewEngl d U.S. Art RAYo WAERAYaEPRIENCSATO Incudebilio grapicr•efe "M ( p prgam) 3dCOeTt L -E nv i Eroa BORpR of E. Nw Y ri.ARm E er Wter...constant = 8.206 x 10.5 atm m3/(gmole-kelvins) T = absolute temperature, kelvins. A temperature of 298K (25 °C) is assumed in the model. The parameter...bottom sediment material are shown in Table 3. Table 2 Concentrations of DDE and Lindane In Water Column Sampling Day DDE, ppt, X ± SD Undane, ppt, X

  2. Cerebral Oxygen Saturation in Children With Congenital Heart Disease and Chronic Hypoxemia.

    PubMed

    Kussman, Barry D; Laussen, Peter C; Benni, Paul B; McGowan, Francis X; McElhinney, Doff B

    2017-07-01

    Increased hemoglobin (Hb) concentration accompanying hypoxemia is a compensatory response to maintain tissue oxygen delivery. Near infrared spectroscopy (NIRS) is used clinically to detect abnormalities in the balance of cerebral tissue oxygen delivery and consumption, including in children with congenital heart disease (CHD). Although NIRS-measured cerebral tissue O2 saturation (ScO2) correlates with arterial oxygen saturation (SaO2), jugular bulb O2 saturation (SjbO2), and Hb, little data exist on the interplay between these factors and cerebral O2 extraction (COE). This study investigated the associations of ScO2 and ΔSaO2-ScO2 with SaO2 and Hb and verified the normal range of ScO2 in children with CHD. Children undergoing cardiac catheterization for CHD were enrolled in a calibration and validation study of the FORE-SIGHT NIRS monitor. Two pairs of simultaneous arterial and jugular bulb samples were drawn for co-oximetry, calculation of a reference ScO2 (REF CX), and estimation of COE. Pearson correlation and linear regression were used to determine relationships between O2 saturation parameters and Hb. Data were also analyzed according to diagnostic group defined as acyanotic (SaO2 ≥ 90%) and cyanotic (SaO2 < 90%). Of 65 children studied, acceptable jugular bulb samples (SjbO2 absolute difference between samples ≤10%) were obtained in 57 (88%). The ΔSaO2-SjbO2, ΔSaO2-ScO2, and ΔSaO2-REF CX were positively correlated with SaO2 and negatively correlated with Hb (all P < .001). Although by diagnostic group ScO2 differed statistically (P = .002), values in the cyanotic patients were within the range considered normal (69% ± 6%). COE estimated by the difference between arterial and jugular bulb O2 content (ΔCaO2-CjbO2, mL O2/100 mL) was not different for cyanotic and acyanotic patients (P = .10), but estimates using ΔSaO2-SjbO2, ΔSaO2-ScO2, or ΔSaO2-ScO2/SaO2 were significantly different between the cyanotic and acyanotic children (P < .001). Children with adequately compensated chronic hypoxemia appear to have ScO2 values within the normal range. The ΔSaO2-ScO2 is inversely related to Hb, with the implication that in the presence of reduced Hb, particularly if coupled with a decreased cardiac output, the ScO2 can fall to values associated with brain injury in laboratory studies.

  3. Genome-Wide Mapping of Collier In Vivo Binding Sites Highlights Its Hierarchical Position in Different Transcription Regulatory Networks

    PubMed Central

    Dubois, Laurence; Bataillé, Laetitia; Painset, Anaïs; Le Gras, Stéphanie; Jost, Bernard; Crozatier, Michèle; Vincent, Alain

    2015-01-01

    Collier, the single Drosophila COE (Collier/EBF/Olf-1) transcription factor, is required in several developmental processes, including head patterning and specification of muscle and neuron identity during embryogenesis. To identify direct Collier (Col) targets in different cell types, we used ChIP-seq to map Col binding sites throughout the genome, at mid-embryogenesis. In vivo Col binding peaks were associated to 415 potential direct target genes. Gene Ontology analysis revealed a strong enrichment in proteins with DNA binding and/or transcription-regulatory properties. Characterization of a selection of candidates, using transgenic CRM-reporter assays, identified direct Col targets in dorso-lateral somatic muscles and specific neuron types in the central nervous system. These data brought new evidence that Col direct control of the expression of the transcription regulators apterous and eyes-absent (eya) is critical to specifying neuronal identities. They also showed that cross-regulation between col and eya in muscle progenitor cells is required for specification of muscle identity, revealing a new parallel between the myogenic regulatory networks operating in Drosophila and vertebrates. Col regulation of eya, both in specific muscle and neuronal lineages, may illustrate one mechanism behind the evolutionary diversification of Col biological roles. PMID:26204530

  4. Evaluation of the fish passage effectiveness of the Bonneville I prototype surface collector using three-dimensional ultrasonic fish tracking - Final Report

    USGS Publications Warehouse

    Faber, D.M; Weiland, M.A.; Moursund, R.A.; Carlson, T.J.; Adams, N.; Rondorf, D.

    2001-01-01

    This report describes tests conducted at Bonneville Dam on the Columbia River in the spring of 2000. The studies used three-dimensional (3D) acoustic telemetry and computational fluid dynamics (CFD) hydraulic modeling techniques to evaluate the response of outmigrating juvenile steelhead (Oncorhynchus mykiss) and yearling chinook (O. tshawytscha) to the Prototype Surface Collector (PSC) installed at Powerhouse I of Bonneville Dam in 1998 to test the concept of using a deep-slot surface bypass collector to divert downstream migrating salmon from turbines. The study was conducted by Pacific Northwest National Laboratory (PNNL), the Waterways Experiment Station of the U.S. Army Corp of Engineers (COE), Asci Corporation, and the U.S. Geological Survey (USGS), and was sponsored by COE’s Portland District. The goal of the study was to observe the three-dimensional behavior of tagged fish (fish bearing ultrasonic micro-transmitters) within 100 meters (m) of the surface flow bypass structure to test hypotheses about the response of migrants to flow stimuli generated by the presence of the surface flow bypass prototype and its operation. Research was done in parallel with radio telemetry studies conducted by USGS and hydroacoustic studies conducted by WES & Asci to evaluate the prototype surface collector.

  5. Nonlinear Wave Chaos and the Random Coupling Model

    NASA Astrophysics Data System (ADS)

    Zhou, Min; Ott, Edward; Antonsen, Thomas M.; Anlage, Steven

    The Random Coupling Model (RCM) has been shown to successfully predict the statistical properties of linear wave chaotic cavities in the highly over-moded regime. It is of interest to extend the RCM to strongly nonlinear systems. To introduce nonlinearity, an active nonlinear circuit is connected to two ports of the wave chaotic 1/4-bowtie cavity. The active nonlinear circuit consists of a frequency multiplier, an amplifier and several passive filters. It acts to double the input frequency in the range from 3.5 GHz to 5 GHz, and operates for microwaves going in only one direction. Measurements are taken between two additional ports of the cavity and we measure the statistics of the second harmonic voltage over an ensemble of realizations of the scattering system. We developed an RCM-based model of this system as two chaotic cavities coupled by means of a nonlinear transfer function. The harmonics received at the output are predicted to be the product of three statistical quantities that describe the three elements correspondingly. Statistical results from simulation, RCM-based modeling, and direct experimental measurements will be compared. ONR under Grant No. N000141512134, AFOSR under COE Grant FA9550-15-1-0171,0 and the Maryland Center for Nanophysics and Advanced Materials.

  6. Coastal monitoring of the May 2005 dredge disposal offshore of Ocean Beach, San Francisco, Calif.

    USGS Publications Warehouse

    Barnard, Patrick L.; Hanes, Daniel M.

    2006-01-01

    Ocean Beach, California, contains an erosion hot spot in the shadow of the San Francisco ebb tidal delta south of Sloat Boulevard that threatens valuable public infrastructure as well as the safe recreational use of the beach. In an effort to reduce the erosion at this location and avoid hazardous navigation conditions at the current disposal site (SF-8), a new plan for the management of sediment dredged annually from the main shipping channel at the mouth of Francisco Bay was implemented in May 2005 by the United States Army Corps of Engineers, San Francisco District (COE). The objective for COE was to perform a test dredge disposal of ~230,000 m3 (300,000 yd3) of sand just offshore of the erosion hot spot, in depths between approximately 9 and 14 m. This disposal site was chosen because it is in a location where the strong tidal currents associated with the mouth of San Francisco Bay and waves can potentially feed sediment toward the littoral zone in the reach of the beach that is experiencing critical erosion. The onshore migration of sediment from the target disposal location might feed the primary longshore bar or the nearshore zone, and provide a buffer to erosion that peaks during winter months when large waves impact the region. The U.S. Geological Survey (USGS), in collaboration with the Sea Floor Mapping Lab (SFML) of California State University, Monterey Bay, monitored the initial bathymetric evolution of the test dredge disposal site and the adjacent coastal region from May 2005 to November 2005. This paper reports on this monitoring effort and assesses the short-term coastal response.

  7. End-of-Life Decision Making in Palliative Care and Recommendations of the Council of Europe: Qualitative Secondary Analysis of Interviews and Observation Field Notes.

    PubMed

    Martins Pereira, Sandra; Fradique, Emília; Hernández-Marrero, Pablo

    2018-05-01

    End-of-life decisions (ELDs) are embedded in clinical, sociocultural, political, economic, and ethical concerns. In 2014, the Council of Europe (CoE) through its Committee on Bioethics launched the "Guide on the decision-making process regarding medical treatment in end-of-life situations," aiming at improving decision-making processes and empowering professionals in making ELDs. To analyze if end-of-life decision making in palliative care (PC) is consistent with this Guide and to identify if disputed/controversial issues are part of current ELDs. Qualitative secondary analysis. Four qualitative datasets, including 44 interviews and 9 team observation field notes from previous studies with PC teams/professionals in Portugal. An analysis grid based on the abovementioned guide was created considering three dimensions: ethical and legal frameworks, decision-making process, and disputed/controversial issues. The majority of the professionals considered the ethical principle of autonomy paramount in end-of-life decision making. Justice and beneficence/nonmaleficence were also valued. Although not mentioned in the Guide, the professionals also considered other ethical principles when making ELDs, namely, responsibility, integrity, and dignity. Most of the interviewees and field notes referred to the collective interprofessional dimension of the decision-making process. Palliative sedation and the wish to hasten death were the most mentioned disputed/controversial issues. The nature, limitations, and benefits of qualitative secondary analysis are discussed. End-of-life decision-making processes made by Portuguese PC teams seem to be consistent with the guidelines of the CoE. Further research is needed about disputed/controversial issues and the actual use, effectiveness, and impact of ethical guidelines for end-of-life decision making on professionals' empowerment and for all parties involved.

  8. A comparison of Thellier-type and multispecimen paleointensity determinations on Pleistocene and historical lava flows from Lanzarote (Canary Islands, Spain)

    NASA Astrophysics Data System (ADS)

    Calvo-Rathert, Manuel; Morales-Contreras, Juan; Carrancho, Ángel; Goguitchaichvili, Avto

    2016-09-01

    Sixteen Miocene, Pleistocene, and historic lava flows have been sampled in Lanzarote (Canary Islands) for paleointensity analysis with both the Coe and multispecimen methods. Besides obtaining new data, the main goal of the study was the comparison of paleointensity results determined with two different techniques. Characteristic Remanent Magnetization (ChRM) directions were obtained in 15 flows, and 12 were chosen for paleointensity determination. In Thellier-type experiments, a selection of reliable paleointensity determinations (43 of 78 studied samples) was performed using sets of criteria of different stringency, trying to relate the quality of results to the strictness of the chosen criteria. Uncorrected and fraction and domain-state corrected multispecimen paleointensity results were obtained in all flows. Results with the Coe method on historical flows either agree with the expected values or show moderately lower ones, but multispecimen determinations display a large deviation from the expected result in one case. No relation can be detected between correct or anomalous results and paleointensity determination quality or rock-magnetic properties. However, results on historical flows suggest that agreement between both methods could be a good indicator of correct determinations. Comparison of results obtained with both methods on seven Pleistocene flows yields an excellent agreement in four and disagreements in three cases. Pleistocene determinations were only accepted if either results from both methods agreed or a result was based on a sufficiently large number (n > 4) of individual Thellier-type determinations. In most Pleistocene flows, a VADM around 5 × 1022 Am2 was observed, although two flows displayed higher values around 9 × 1022 Am2.

  9. [The dose response decrease of lung function associated with the urinary polycyclic aromatic hydrocarbons metabolites in coke oven workers].

    PubMed

    Hu, Die; Deng, Qi-fei; Huang, Su-li; He, Yun-feng; Guo, Huan; Wu, Tang-chun

    2012-12-01

    To analyze the relationship between metabolites of polycyclic aromatic hydrocarbons (PAHs) and lung function in coke oven workers, and to provide scientific basis for further exploring the potential mechanism and developing the preventing strategies of the workers' early lung damage. We measured carbon monoxide, sulfur dioxide, benzene soluble matter, particulate matters, and PAHs at different workplaces of a coke oven plant. Detailed information on demography and occupational health condition of 912 workers were collected. We divided these workers into control group and coke oven group according to their workplaces and the different concentrations of COEs in the environment. We detected 10 urinary PAH metabolites and lung function using gas chromatography-mass spectrometry and spirometric tests, respectively. FEV(1.0) (91.12 ± 13.31) and FEV(1.0)/FVC (108.61 ± 20.37) of the coke oven group is significantly lower than the control group (94.16 ± 15.57, 113.45 ± 19.70). In the coke oven group, the hydroxyphenanthrene and 1-hydroxypyrene are negatively correlated with FEV(1.0)/FVC (β = -0.136, β = -0.100), Ptrend < 0.05 for all. The dose response decrease of lung function is associated with the urinary PAH metabolites in coke oven workers. Indicated that the long exposure to PAHs may cause the early lung damage in coke oven workers, phenanthrene and pyrene may be the main factors.

  10. Blueprint for Change. Report of the Process Action Team on Military Specifications and Standards

    DTIC Science & Technology

    1994-03-01

    and Standards 6. AlfT"OR( S ) DoD Process Action Team N/A 7. PRFORP-INQ ORGAN-AT!,N NA t( S ) ANO II PERFORAM NG ORGANI/AHIUN HQ, U.S. Army Materiel Command...AGENCY NANI,: , S ) AND ADIPESSES) 10. SPONSORiNG, MONITORING Deputy Under Secretary of Defense for Acquisition Reform AGEN4CY REPORT NUMBER Ms. Colleen...special markings in all capitals (e.g. Jan SB). u’t coe at Ioo’J tht- yearj NC)FORN, REL, ITAR). Blck3.1 V1, -)" -Z". f It- Ir r -D It S Cov T --,D OD

  11. National Dam Inspection Program. Ingham Creek (Aquetong Lake) Dam (NDI ID PA 00224, PA DER 9-49) Delaware River Basin, Ingham Creek, Pennsylvania. Phase I Inspection Report,

    DTIC Science & Technology

    1981-04-01

    Delaware River Basing Ingham Justif icaticn--- L Creek, Pennsylvania. Phase I Inspection Do DEL-AWARE RIVER BASIN Availabilit T Co~es Avail and/or D...about 1.5H:IV and an unknown upstream slope below the water surface. The dam impounds a reservoir with a normal pool surface area of 12.4 acres and a...deep. It was once used to direct water to a mill downstream of the dam and is now in poor condition. The spillway Design Flood (SDF) chosen for this

  12. Disease management as a performance improvement strategy.

    PubMed

    McClatchey, S

    2001-11-01

    Disease management is a strategy of organizing care and services for a patient population across the continuum. It is characterized by a population database, interdisciplinary and interagency collaboration, and evidence-based clinical information. The effectiveness of a disease management program has been measured by a combination of clinical, financial, and quality of life outcomes. In early 1997, driven by a strategic planning process that established three Centers of Excellence (COE), we implemented disease management as the foundation for a new approach to performance improvement utilizing five key strategies. The five implementation strategies are outlined, in addition to a review of the key elements in outcome achievement.

  13. Electric Power Generation from Low to Intermediate Temperature Resourcces

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gosnold, William; Mann, Michael; Salehfar, Hossein

    The UND-CLR Binary Geothermal Power Plant was a collaborative effort of the U.S. Department of Energy (DOE), Continental Resources, Inc. (CRL), Slope Electric Cooperative (SEC), Access Energy, LLC (AE), Basin Electric Cooperative (BEC), Olson Construction, the North Dakota Industrial Commission Renewable Energy Council (NDIC-REC), the North Dakota Department of Commerce Centers of Excellence Program (NDDC-COE), and the University of North Dakota (UND). The primary objective of project was to demonstrate/test the technical and economic feasibility of generating electricity from non-conventional, low-temperature (90 ºC to 150 °C) geothermal resources using binary technology. CLR provided the access to 98 ºC water flowingmore » at 51 l s-1 at the Davis Water Injection Plan in Bowman County, ND. Funding for the project was from DOE –GTO, NDIC-REC, NDD-COE, and BEC. Logistics, on-site construction, and power grid access were facilitated by Slope Electric Cooperative and Olson Construction. Access Energy supplied prototype organic Rankine Cycle engines for the project. The potential power output from this project is 250 kW at a cost of $3,400 per kW. A key factor in the economics of this project is a significant advance in binary power technology by Access Energy, LLC. Other commercially available ORC engines have efficiencies 8 to 10 percent and produce 50 to 250 kW per unit. The AE ORC units are designed to generate 125 kW with efficiencies up to 14 percent and they can be installed in arrays of tens of units to produce several MW of power where geothermal waters are available. This demonstration project is small but the potential for large-scale development in deeper, hotter formations is promising. The UND team’s analysis of the entire Williston Basin using data on porosity, formation thicknesses, and fluid temperatures reveals that 4.0 x 1019 Joules of energy is available and that 1.36 x 109 MWh of power could be produced using ORC binary power plants. Much of the infrastructure necessary to develop extensive geothermal power in the Williston Basin exists as abandoned oil and gas wells. Re-completing wells for water production could provide local power throughout the basin thus reducing power loss through transmission over long distances. Water production in normal oil and gas operations is relatively low by design, but it could be one to two orders of magnitude greater in wells completed and pumped for water production. A promising method for geothermal power production recognized in this project is drilling horizontal open-hole wells in the permeable carbonate aquifers. Horizontal drilling in the aquifers increases borehole exposure to the resource and consequently increases the capacity for fluid production by up to an order of magnitude.« less

  14. CO 2 capture from IGCC gas streams using the AC-ABC process

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Nagar, Anoop; McLaughlin, Elisabeth; Hornbostel, Marc

    The objective of this project was to develop a novel, low-cost CO 2 capture process from pre-combustion gas streams. The bench-scale work was conducted at the SRI International. A 0.15-MWe integrated pilot plant was constructed and operated for over 700 hours at the National Carbon Capture Center, Wilsonville, AL. The AC-ABC (ammonium carbonate-ammonium bicarbonate) process for capture of CO 2 and H 2S from the pre-combustion gas stream offers many advantages over Selexol-based technology. The process relies on the simple chemistry of the NH 3-CO 2-H 2O-H 2S system and on the ability of the aqueous ammoniated solution to absorbmore » CO 2 at near ambient temperatures and to release it as a high-purity, high-pressure gas at a moderately elevated regeneration temperature. It is estimated the increase in cost of electricity (COE) with the AC-ABC process will be ~ 30%, and the cost of CO 2 captured is projected to be less than $27/metric ton of CO 2 while meeting 90% CO 2 capture goal. The Bechtel Pressure Swing Claus (BPSC) is a complementary technology offered by Bechtel Hydrocarbon Technology Solutions, Inc. BPSC is a high-pressure, sub-dew-point Claus process that allows for nearly complete removal of H 2S from a gas stream. It operates at gasifier pressures and moderate temperatures and does not affect CO 2 content. When coupled with AC-ABC, the combined technologies allow a nearly pure CO 2 stream to be captured at high pressure, something which Selexol and other solvent-based technologies cannot achieve.« less

  15. Habitat Evaluation Procedures (HEP) Report; Steigerwald Lake National Wildlife Refuge, Technical Report 2000-2001.

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Allard, Donna

    2001-09-01

    Steigenvald Lake National Wildlife Refuge (NWR, refuge) was established as a result of the U. S. Army Corps of Engineers (COE) transferring ownership of the Stevenson tract located in the historic Steigerwald Lake site to the U.S. Fish and Wildlife Service (FWS, Service) for the mitigation of the fish and wildlife losses associated with the construction of a second powerhouse at the Bonneville Dam on the Columbia River and relocation of the town of North Bonneville (Public Law 98-396). The construction project was completed in 1983 and resulted in the loss of approximately 577 acres of habitat on the Washingtonmore » shore of the Columbia River (USFWS, 1982). The COE determined that acquisition and development of the Steigenvald Lake area, along with other on-site project management actions, would meet their legal obligation to mitigate for these impacts (USCOE, 1985). Mitigation requirements included restoration and enhancement of this property to increase overall habitat diversity and productivity. From 1994 to 1999, 317 acres of additional lands, consisting of four tracts of contiguous land, were added to the original refuge with Bonneville Power Administration (BPA) funds provided through the Washington Wildlife Mitigation Agreement. These tracts comprised Straub (191 acres), James (90 acres), Burlington Northern (27 acres), and Bliss (9 acres). Refer to Figure 1. Under this Agreement, BPA budgeted $2,730,000 to the Service for 'the protection, mitigation, and enhancement of wildlife and wildlife habitat that was adversely affected by the construction of Federal hydroelectric dams on the Columbia River or its tributaries' in the state of Washington (BPA, 1993). Lands acquired for mitigation resulting from BPA actions are evaluated using the habitat evaluation procedures (HEP) methodology, which quantifies how many Habitat Units (HUs) are to be credited to BPA. HUs or credits gained lessen BPA's debt, which was formally tabulated in the Federal Columbia River Power System Loss Assessments and adopted as part of the Northwest Power Planning Council's Fish and Wildlife Program as a BPA obligation (BPA, 1994). Steigenvald Lake NWR is located in southwest Washington (Clark County), within the Columbia River Gorge National Scenic Area. Historically part of the Columbia River flood plain, the refuge area was disconnected from the river by a series of dikes constructed by the COE for flood control in 1966. An aerial photograph from 1948 portrays this area as an exceedingly complex mosaic of open water, wetlands, sloughs, willow and cottonwood stands, wet meadows, upland pastures, and agricultural fields, which once supported a large assemblage of fish and wildlife populations. Eliminating the threat of periodic inundation by the Columbia River allowed landowners to more completely convert the area into upland pasture and farmland through channelization and removal of standing water. Native pastures were 'improved' for grazing by the introduction of non-native fescues, orchard grass, ryegrass, and numerous clovers. Although efforts to drain the lake were not entirely successful, wetland values were still significantly reduced.« less

  16. Development of Novel Carbon Sorbents for CO{sub 2} Capture

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Krishnan, Gopala; Hornbostel, Marc; Bao, Jianer

    2013-11-30

    An innovative, low-cost, and low-energy-consuming carbon dioxide (CO{sub 2}) capture technology was developed, based on CO{sub 2}adsorption on a high-capacity and durable carbon sorbent. This report describes the (1) performance of the concept on a bench-scale system; (2) results of parametric tests to determine the optimum operating conditions; (3) results of the testing with a flue gas from coal-fired boilers; and (4) evaluation of the technical and economic viability of the technology. The process uses a falling bed of carbon sorbent microbeads to separate the flue gas into two streams: a CO{sub 2} -lean flue gas stream from which >more » 90% of the CP{sub 2} is removed and a pure stream of CO{sub 2} that is ready for compression and sequestration. The carbo sorbent microbeads have several unique properties such as high CO{sub 2} capacity, low heat of adsorption and desorption (25 to 28 kJ/mole), mechanically robust, and rapid adsorption and desorption rates. The capture of CO{sub 2} from the flue gas is performed at near ambient temperatures in whic the sorbent microbeads flow down by gravity counter-current with the up-flow of the flue gas. The adsorbed CO{sub 2} is stripped by heating the CO{sub 2}-loaded sorbent to - 100°C, in contact with low-pressure (- 5 psig) steam in a section at the bottom of the adsorber. The regenerated sorben is dehydrated of adsorbed moisture, cooled, and lifted back to the adsorber. The CO{sub 2} from the desorber is essentially pure and can be dehydrated, compressed, and transported to a sequestration site. Bench-scale tests using a simulated flue gas showed that the integrated system can be operated to provide > 90% CO{sub 2} capture from a 15% CO{sub 2} stream in the adsorber and produce > 98% CO{sub 2} at the outlet of the stripper. Long-term tests ( 1,000 cycles) showed that the system can be operated reliably without sorbent agglomeration or attrition. The bench-scale reactor was also operated using a flue gas stream from a coal-fired boil at the University of Toledo campus for about 135 h, comprising 7,000 cycles of adsorption and desorption using the desulfurized flue gas that contained only 4.5% v/v CO{sub 2}. A capture efficiency of 85 to 95% CO{sub 2} was achieved under steady-state conditi ons. The CO{sub 2} adsorption capacity did not change significantly during the field test, as determined from the CO{sub 2} adsorptio isotherms of fresh and used sorbents. The process is also being tested using the flue gas from a PC-fired power plant at the National Carbon Capture Center (NCCC), Wilsonville, AL. The cost of electricity was calculated for CO{sub 2} capture using the carbon sorbent and compared with the no-CO{sub 2} capture and CO{sub 2} capture with an amine-based system. The increase i the levelized cost of electricity (L-COE) is about 37% for CO{sub 2} capture using the carbon sorbent in comparison to 80% for an amine-based system, demonstrating the economic advantage of C capture using the carbon sorbent. The 37% increase in the L-COE corresponds to a cost of capture of $30/ton of CO{sub 2}, including compression costs, capital cost for the capture system, and increased plant operating and capital costs to make up for reduced plant efficiency. Preliminary sensitivity analyses showed capital costs, pressure drops in the adsorber, and steam requirement for the regenerator are the major variables in determining the cost of CO{sub 2} capture. The results indicate that further long-term testing with a flue gas from a pulverized coal­ fired boiler should be performed to obtain additional data relating to the effects of flue gas contaminants, the ability to reduce pressure drop by using alternate structural packing , and the use of low-cost construction materials.« less

  17. Three-dimensional modelling and three-dimensional printing in pediatric and congenital cardiac surgery.

    PubMed

    Kiraly, Laszlo

    2018-04-01

    Three-dimensional (3D) modelling and printing methods greatly support advances in individualized medicine and surgery. In pediatric and congenital cardiac surgery, personalized imaging and 3D modelling presents with a range of advantages, e.g., better understanding of complex anatomy, interactivity and hands-on approach, possibility for preoperative surgical planning and virtual surgery, ability to assess expected results, and improved communication within the multidisciplinary team and with patients. 3D virtual and printed models often add important new anatomical findings and prompt alternative operative scenarios. For the lack of critical mass of evidence, controlled randomized trials, however, most of these general benefits remain anecdotal. For an individual surgical case-scenario, prior knowledge, preparedness and possibility of emulation are indispensable in raising patient-safety. It is advocated that added value of 3D printing in healthcare could be raised by establishment of a multidisciplinary centre of excellence (COE). Policymakers, research scientists, clinicians, as well as health care financers and local entrepreneurs should cooperate and communicate along a legal framework and established scientific guidelines for the clinical benefit of patients, and towards financial sustainability. It is expected that besides the proven utility of 3D printed patient-specific anatomical models, 3D printing will have a major role in pediatric and congenital cardiac surgery by providing individually customized implants and prostheses, especially in combination with evolving techniques of bioprinting.

  18. Three-dimensional modelling and three-dimensional printing in pediatric and congenital cardiac surgery

    PubMed Central

    2018-01-01

    Three-dimensional (3D) modelling and printing methods greatly support advances in individualized medicine and surgery. In pediatric and congenital cardiac surgery, personalized imaging and 3D modelling presents with a range of advantages, e.g., better understanding of complex anatomy, interactivity and hands-on approach, possibility for preoperative surgical planning and virtual surgery, ability to assess expected results, and improved communication within the multidisciplinary team and with patients. 3D virtual and printed models often add important new anatomical findings and prompt alternative operative scenarios. For the lack of critical mass of evidence, controlled randomized trials, however, most of these general benefits remain anecdotal. For an individual surgical case-scenario, prior knowledge, preparedness and possibility of emulation are indispensable in raising patient-safety. It is advocated that added value of 3D printing in healthcare could be raised by establishment of a multidisciplinary centre of excellence (COE). Policymakers, research scientists, clinicians, as well as health care financers and local entrepreneurs should cooperate and communicate along a legal framework and established scientific guidelines for the clinical benefit of patients, and towards financial sustainability. It is expected that besides the proven utility of 3D printed patient-specific anatomical models, 3D printing will have a major role in pediatric and congenital cardiac surgery by providing individually customized implants and prostheses, especially in combination with evolving techniques of bioprinting. PMID:29770294

  19. A Probablistic Diagram to Guide Chemical Design with ...

    EPA Pesticide Factsheets

    Toxicity is a concern with many chemicals currently in commerce, and with new chemicals that are introduced each year. The standard approach to testing chemicals is to run studies in laboratory animals (e.g. rats, mice, dogs), but because of the expense of these studies and concerns for animal welfare, few chemicals besides pharmaceuticals and pesticides are fully tested. Over the last decade there have been significant developments in the field of computational toxicology which combines in vitro tests and computational models. The ultimate goal of this ?field is to test all chemicals in a rapid, cost effective manner with minimal use of animals. One of the simplest measures of toxicity is provided by high-throughput in vitro cytotoxicity assays, which measure the concentration of a chemical that kills particular types of cells. Chemicals that are cytotoxic at low concentrations tend to be more toxic to animals than chemicals that are less cytotoxic. We employed molecular characteristics derived from density functional theory (DFT) and predicted values of log(octanol-water partition coe?fficient) (logP)to construct a design variable space, and built a predictive model for cytotoxicity using a Naive Bayesian algorithm. External evaluation showed that the area under the curve (AUC) for the receiver operating characteristic (ROC) of the model to be 0.81. Using this model, we provide design rules to help synthetic chemists minimize the chance that a newly synthesize

  20. Apparatus and method for modifying the operation of a robotic vehicle in a real environment, to emulate the operation of the robotic vehicle operating in a mixed reality environment

    DOEpatents

    Garretson, Justin R [Albuquerque, NM; Parker, Eric P [Albuquerque, NM; Gladwell, T Scott [Albuquerque, NM; Rigdon, J Brian [Edgewood, NM; Oppel, III, Fred J.

    2012-05-29

    Apparatus and methods for modifying the operation of a robotic vehicle in a real environment to emulate the operation of the robotic vehicle in a mixed reality environment include a vehicle sensing system having a communications module attached to the robotic vehicle for communicating operating parameters related to the robotic vehicle in a real environment to a simulation controller for simulating the operation of the robotic vehicle in a mixed (live, virtual and constructive) environment wherein the affects of virtual and constructive entities on the operation of the robotic vehicle (and vice versa) are simulated. These effects are communicated to the vehicle sensing system which generates a modified control command for the robotic vehicle including the effects of virtual and constructive entities, causing the robot in the real environment to behave as if virtual and constructive entities existed in the real environment.

  1. Evaporation Rates of Chemical Warfare Agents Using 5 cm Wind Tunnels, IV. VX From Glass

    DTIC Science & Technology

    2010-06-01

    J »- o 3? a? j5 d £ * fi SC s? s? s s CO 00 ^ StSRRKf 8 tD Irt « 6 « « »§ ooopooooo WWUJfjJUJUJLULJJlJJ i-0)rtNO)NNT-(p OT...go? * • 8. E • g T5 ti w 5> w 3 ’ flj £ g> A. ft. ft. 3 *° ro (U (U « IB t_> < < < I 8...SCOCOCOCpCOeOCiCDCOCO OOlOOi-rWWnO ! K f^-" r^ I--• K r^ i^ • tD OJ CO S o> c O OJ CM CM (%) 6uiu!etuou juo6v

  2. Recent Development of SOFC Metallic Interconnect

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Wu JW, Liu XB

    2010-04-01

    Interest in solid oxide fuel cells (SOFC) stems from their higher e±ciencies and lower levels of emitted pollu- tants, compared to traditional power production methods. Interconnects are a critical part in SOFC stacks, which connect cells in series electrically, and also separate air or oxygen at the cathode side from fuel at the anode side. Therefore, the requirements of interconnects are the most demanding, i:e:, to maintain high elec- trical conductivity, good stability in both reducing and oxidizing atmospheres, and close coe±cient of thermal expansion (CTE) match and good compatibility with other SOFC ceramic components. The paper reviewed the interconnectmore » materials, and coatings for metallic interconnect materials.« less

  3. Effects of flood control alternatives on fish and wildlife resources of the Malheur-Harney lakes basin

    USGS Publications Warehouse

    Hamilton, David B.; Auble, Gregor T.; Ellison, Richard A.; Roelle, James E.

    1985-01-01

    Malheur Lake is the largest freshwater marsh in the western contiguous United States and is one of the main management units of the Malheur National Wildlife Refuge in southeastern Oregon. The marsh provides excellent waterfowl production habitat as well as vital migration habitats for birds in the Pacific flyway. Water shortages have typically been a problem in this semiarid area; however, record snowfalls and cool summers have recently caused Malheur Lake to rise to its highest level in recorded history. This has resulted in the loss of approximately 57,000 acres of important wildlife habitat as well as extensive flooding of local ranches, roads, and railroad lines. Because of the importance of the Refuge, any water management plan for the Malheur-Harney Lakes Basin needs to consider the impact of management alternatives on the hydrology of Malheur Lake. The facilitated modeling workshop described in this report was conducted January 14-18, 1985, under the joint sponsorship of the Portland Ecological Services Field Office and the Malheur National Wildlife Refuge, Region 1, U.S. Fish and Wildlife Service (FWS). The Portland Field Office is responsible for FWS reporting requirements on Federal water resource projects while the Refuge staff has management responsibility for much of the land affected by high water levels in the Malheur-Harney Lakes Basin. The primary objective of the workshop was to begin gathering and analyzing information concerning potential fish and wildlife impacts, needs, and opportunities associated with proposed U.S. Army Corps of Engineers (COE) flood control alternatives for Malheur Lake. The workshop was structured around the formulation of a computer model that would simulate the hydrologic effects of the various alternatives and any concommitant changes in vegetation communities and wildlife use patterns. The simulation model is composed of three connected submodels. The Hydrology submodel calculates changes in lake volume, elevation, and surface area, as well as changes in water quality, that result from the proposed water management projects (upstream storage, upstream diversions, drainage canals) and the no action alternative. The Vegetation submodel determines associated changes in the areal extent of wetland and upland vegetation communities. Finally, the Wildlife submodel calculates indices of abundance or habitat suitability for colonial nesting birds (great egret, double-crested cormorant, white-faced ibis), greater sandhill crane, diving ducks, tundra swan, dabbling ducks, and Canada goose based on hydrologic and vegetation conditions. The model represents the Malheur-Harney Lakes Basin, but provides water quantity and quality indicators associated with additional flows that might occur in the Malheur River Basin. Several management scenarios, representing various flood control alternatives and assumptions concerning future runoff, were run to analyze model behavior. Scenario results are not intended as an analysis of all potential management actions or assumptions concerning future runoff. Rather, they demonstrate the type of analysis that could be conducted if the model was sufficiently refined and tested. Early in a model development project, the process of building the model is usually of greater benefit than the model itself. The model building process stimulates interaction among agencies, assists in integrating existing information, and helps identify research needs. These benefits usually accrue even in the absence of real predictive power in the resulting model. This workshop initiated interaction among the primary State and Federal resource and development agencies in a nonadversarial forum. The exchange of information and expertise among agencies provided the FWS with the best information currently available for use in the Planning Aid Letter it will develop at the Reconnaissance state of the COE study. If the COE subsequently initiates a Feasability Study, this information will be refined further and will aid the FWS in preparing its Coordination Act Report on any flood control alternative proposed by the COE. The model building and testing process also helped identify model limitations and more general information needs that should be evaluated for further study prior to preparation of an FWS Coordination Act Report. Major needs associated with the Hydrology submodel include a more detailed representation of hydrologic units (separately consider Harney Lake, Mud Lake, and Malheur Lake or the three hydrological units within Malheur Lake, rather than a combined lake system) and explicitly representation of groundwater storage and discharge in water budget calculations. A better representation of the hydrological units will require more detailed topographic data for the basin, capacity-elevation and elevation-surface area curves for each unit, and better water flow data between the units. Additional water quality parameters and constraints on proposed canal operation due to conditions in the Malheur River might also be added. Key Vegetation submodel needs include fine-tuning existing vegetation relationships in the model and adding relationships to address the influence of historical conditions on vegetation development, effects of very rapid changes in lake level, effects of wildlife populations (e.g., carp, muskrat), responses of vegetation to habitat management actions (e.g, haying, grazing, burning), and better representation of sago pondweed dynamics. A complementary geographic information system might also be developed for spatial analyses. Major needs that should be evaluated for the Wildlife submodel include addition of other wildlife species that have important effects on habitat on the Refuge (e.g., carp, muskrat) and consideration of additional life-cycle requisites and controlling variable for species presently in the model. Some of these limitations could perhaps be overcome if historical data on habitat conditions were developed to use with historical data on wildlife populations.

  4. Numerical Ergonomics Analysis in Operation Environment of CNC Machine

    NASA Astrophysics Data System (ADS)

    Wong, S. F.; Yang, Z. X.

    2010-05-01

    The performance of operator will be affected by different operation environments [1]. Moreover, poor operation environment may cause health problems of the operator [2]. Physical and psychological considerations are two main factors that will affect the performance of operator under different conditions of operation environment. In this paper, applying scientific and systematic methods find out the pivot elements in the field of physical and psychological factors. There are five main factors including light, temperature, noise, air flow and space that are analyzed. A numerical ergonomics model has been built up regarding the analysis results which can support to advance the design of operation environment. Moreover, the output of numerical ergonomic model can provide the safe, comfortable, more productive conditions for the operator.

  5. Theoretical Modeling for the X-ray Spectroscopy of Iron-bearing MgSiO3 under High Pressure

    NASA Astrophysics Data System (ADS)

    Wang, X.; Tsuchiya, T.

    2012-12-01

    The behaviors of iron (Fe) in MgSiO3 perovskite, including valence state, spin state, and chemical environments, at high pressures are of fundamental importance for more detailed understanding the properties of the Earth's lower mantle. The pressure induced spin transition of Fe-bearing MgO and MgSiO3 are detected often by using high-resolution K-edge X-ray emission spectroscopy (XES) [1,2,3] and confirmed by theoretical simulations. [4,5] Since the Fe K-edge XES is associated to the 3p orbital, which is far from the valence orbitals (3d and 4s), it provides no information about its coordination environments. However, the Fe L-edge XES and X-ray absorption spectroscopy (XAS) can directly present the distribution and intensity of Fe-3d character. To identify both the spin states and the coordination environments of iron-bearing MgSiO3, we systematically investigate the L-edge XAS, XES and X-ray photoelectron (XPS) spectroscopy of Fe2+- and Fe3+-bearing MgSiO3 under high pressure by using the first-principles density functional method combined with the slater-transition method. Our results show that Fe2+ and Fe3+ can be distinguished easily by taking the XPS spectra. The spin transition of Fe2+ and Fe3+ can also be clearly certified by XAS and XES. Interestingly, the broadness of L-edge XES of Fe changes depending on the iron position, meaning that its coordination environment might also be distinguishable by using high-resolution XES measurements. Research supported by the Ehime University G-COE program and KAKENHI. [1] James Badro, Guillaume Fiquet, FranÇois Guyot, Jean-Pascal Rueff, Viktor V. Struzhkin, György VankÓ, and Giulio Monaco. Science 300, 789 (2003), [2] James Badro, Jean-Pascal Rueff, György VankÓ, Giulio Monaco, Guillaume Fiquet, and FranÇois Guyot, Science 305, 383 (2004), [3] Jung-Fu Lin, Viktor V. Struzhkin, Steven D. Jacobsen, Michael Y. Hu, Paul Chow, Jennifer Kung, Haozhe Liu, Ho-kwang Mao, and Gussell J. Hemley, Nature 436, 377 (2005). [4] Taku Tsuchiya, Renata M. Wentzcovitch, Cesar R.S. da Silva, and Stefano de Gironcoli, Phys. Rev. Lett. 96, 198501 (2006). [4] Han Hsu, Peter Blaha, Matteo Cococcioni, and Renata M. Wentzcovitch, Phys. Rev. Lett. 106, 118501 (2011).

  6. Environmental Resources of Selected Areas of Hawaii: Ecological Resources (DRAFT)

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Trettin, C.C.; Tolbert, V.R.; Jones, A.T.

    1994-06-01

    This report has been prepared to make available and archive the background scientific data and related information collected on ecological resources during the preparation of the environmental impact statement (EIS) for Phases 3 and 4 of the Hawaii Geothermal Project (HGP) as defined by the state of Hawaii in its April 1989 proposal to Congress. The U.S. Department of Energy (COE) published a notice in the Federal Register on May 17, 1994 (Fed. Regist. 5925638) withdrawing its Notice of Intent (Fed. Regst. 575433) of February 14, 1992, to prepare the HGP-EIS. Since the state of Hawaii is no longer pursuingmore » or planning to pursue the HGP, DOE considers the project to be terminated. The background scientific data and related information presented in this report focus on several areas of Hawaii County, including the southeastern coast, a potential development corridor along the Saddle Road between Hilo and the North Kohala District on the northwestern coast, and on the southeastern coast of Maui. In this report, reference is made to these areas as study areas rather than as areas where proposed or alternative facilities of the HGP would be located. The resource areas addressed herein include terrestrial ecology, aquatic ecology, and marine ecology. The scientific background data and related information is being made available for future research in these areas. This report describes the environmental resources present in the areas studied (i.e., the affected environment) and does not represent an assessment of environmental impacts.« less

  7. Design and optimization of smart grid system based on renewable energy in Nyamuk Island, Karimunjawa district, Central Java

    NASA Astrophysics Data System (ADS)

    Novitasari, D.; Indartono, Y. S.; Rachmidha, T. D.; Reksowardojo, I. K.; Irsyad, M.

    2017-03-01

    Nyamuk Island in Karimunjawa District is one of the regions in Java that has no access to electricity grid. The electricity in Nyamuk Island relies on diesel engine which is managed by local government and only operated for 6 hours per day. It occurs as a consequence of high fuel cost. A study on smart micro grid system based on renewable energy was conducted in Combustion Engine and Propulsion System Laboratory of Institut Teknologi Bandung by using 1 kWp solar panels and a 3 kW bio based diesel engine. The fuels used to run the bio based diesel engine were diesel, virgin coconut oil and pure palm oil. The results show that the smart grid system run well at varying load and also with different fuel. Based on the experiments, average inverter efficiency was about 87%. This experiments proved that the use of biofuels had no effects to the overall system performance. Based on the results of prototype experiments, this paper will focus on design and optimization of smart micro grid system using HOMER software for Nyamuk Island. The design consists of (1) a diesel engine existing in Nyamuk Island whose fuel was diesel, (2) a lister engine whose fuel was from vegetable oil from Callophyllum inophyllum, (3) solar panels, (4) batteries and (5) converter. In this simulation, the existing diesel engine was set to operate 2 hours per day, while operating time of the lister engine has been varied with several scenarios. In scenario I, the lister engine was operated 5 hours per day, in scenario II the lister engine was operated 24 hours per day and in scenario III the lister engine was operated 8 hours per week in the weekend. In addition, a design using a modified diesel engine was conducted as well with an assumption that the modified cost was about 10% of new diesel engine cost. By modifying the diesel engine, the system will not need a lister engine. Assessments has been done to evaluate the designs, and the result shows that the optimal value obtains by the lister engine being operated for 24 hours a day in which the capacity of each component was 27 kWp PV, 7 kW lister engine, 26 kVA existing diesel engine, 40 kW converter and 128 batteries. The result is based on the lowest value of Net Present Cost (NPC) of 542.682 and Cost Of Electricity (COE) of 0.49.

  8. Critical operations capabilities in a high cost environment: a multiple case study

    NASA Astrophysics Data System (ADS)

    Sansone, C.; Hilletofth, P.; Eriksson, D.

    2018-04-01

    Operations capabilities have been a popular research area for many years and several frameworks have been proposed in the literature. The current frameworks do not take specific contexts into consideration, for instance a high cost environment. This research gap is of particular interest since a manufacturing relocation process has been ongoing the last decades, leading to a huge amount of manufacturing being moved from high to low cost environments. The purpose of this study is to identify critical operations capabilities in a high cost environment. The two research questions were: What are the critical operations capabilities dimensions in a high cost environment? What are the critical operations capabilities in a high cost environment? A multiple case study was conducted and three Swedish manufacturing firms were selected. The study was based on the investigation of an existing framework of operations capabilities. The main dimensions of operations capabilities included in the framework were: cost, quality, delivery, flexibility, service, innovation and environment. Each of the dimensions included two or more operations capabilities. The findings confirmed the validity of the framework and its usefulness in a high cost environment and a new operations capability was revealed (employee flexibility).

  9. Pulse Wave Transit Time Measurements of Cardiac Output in Septic Shock Patients: A Comparison of the Estimated Continuous Cardiac Output System with Transthoracic Echocardiography.

    PubMed

    Feissel, Marc; Aho, Ludwig Serge; Georgiev, Stefan; Tapponnier, Romain; Badie, Julio; Bruyère, Rémi; Quenot, Jean-Pierre

    2015-01-01

    We determined reliability of cardiac output (CO) measured by pulse wave transit time cardiac output system (esCCO system; COesCCO) vs transthoracic echocardiography (COTTE) in mechanically ventilated patients in the early phase of septic shock. A secondary objective was to assess ability of esCCO to detect change in CO after fluid infusion. Mechanically ventilated patients admitted to the ICU, aged >18 years, in sinus rhythm, in the early phase of septic shock were prospectively included. We performed fluid infusion of 500 ml of crystalloid solution over 20 minutes and recorded CO by EsCCO and TTE immediately before (T0) and 5 minutes after (T1) fluid administration. Patients were divided into 2 groups (responders and non-responders) according to a threshold of 15% increase in COTTE in response to volume expansion. In total, 25 patients were included, average 64±15 years, 15 (60%) were men. Average SAPSII and SOFA scores were 55±21.3 and 13±2, respectively. ICU mortality was 36%. Mean cardiac output at T0 was 5.8±1.35 L/min by esCCO and 5.27±1.17 L/min by COTTE. At T1, respective values were 6.63 ± 1.57 L/min for esCCO and 6.10±1.29 L/min for COTTE. Overall, 12 patients were classified as responders, 13 as non-responders by the reference method. A threshold of 11% increase in COesCCO was found to discriminate responders from non-responders with a sensitivity of 83% (95% CI, 0.52-0.98) and a specificity of 77% (95% CI, 0.46-0.95). We show strong correlation esCCO and echocardiography for measuring CO, and change in CO after fluid infusion in ICU patients.

  10. Further studies on the problems of geomagnetic field intensity determination from archaeological baked clay materials

    NASA Astrophysics Data System (ADS)

    Kostadinova-Avramova, M.; Kovacheva, M.

    2015-10-01

    Archaeological baked clay remains provide valuable information about the geomagnetic field in historical past, but determination of the geomagnetic field characteristics, especially intensity, is often a difficult task. This study was undertaken to elucidate the reasons for unsuccessful intensity determination experiments obtained from two different Bulgarian archaeological sites (Nessebar - Early Byzantine period and Malenovo - Early Iron Age). With this aim, artificial clay samples were formed in the laboratory and investigated. The clay used for the artificial samples preparation differs according to its initial state. Nessebar clay was baked in the antiquity, but Malenovo clay was raw, taken from the clay deposit near the site. The obtained artificial samples were repeatedly heated eight times in known magnetic field to 700 °C. X-ray diffraction analyses and rock-magnetic experiments were performed to obtain information about the mineralogical content and magnetic properties of the initial and laboratory heated clays. Two different protocols were applied for the intensity determination-Coe version of Thellier and Thellier method and multispecimen parallel differential pTRM protocol. Various combinations of laboratory fields and mutual positions of the directions of laboratory field and carried thermoremanence were used in the performed Coe experiment. The obtained results indicate that the failure of this experiment is probably related to unfavourable grain sizes of the prevailing magnetic carriers combined with the chosen experimental conditions. The multispecimen parallel differential pTRM protocol in its original form gives excellent results for the artificial samples, but failed for the real samples (samples coming from previously studied kilns of Nessebar and Malenovo sites). Obviously the strong dependence of this method on the homogeneity of the used subsamples hinders its implementation in its original form for archaeomaterials. The latter are often heterogeneous due to variable heating conditions in the different parts of the archaeological structures. The study draws attention to the importance of multiple heating for the stabilization of grain size distribution in baked clay materials and the need of elucidation of this question.

  11. Reduced serum club cell protein as a pulmonary damage marker for chronic fine particulate matter exposure in Chinese population.

    PubMed

    Wang, Yanhua; Duan, Huawei; Meng, Tao; Shen, Meili; Ji, Qianpeng; Xing, Jie; Wang, Qingrong; Wang, Ting; Niu, Yong; Yu, Tao; Liu, Zhong; Jia, Hongbing; Zhan, Yuliang; Chen, Wen; Zhang, Zhihu; Su, Wenge; Dai, Yufei; Zhang, Xuchun; Zheng, Yuxin

    2018-03-01

    Exposure to fine particulate matter (PM 2.5 ) pollution is associated with increased morbidity and mortality from respiratory diseases. However, few population-based studies have been conducted to assess the alterations in circulating pulmonary proteins due to long-term PM 2.5 exposure. We designed a two-stage study. In the first stage (training set), we assessed the associations between PM 2.5 exposure and levels of pulmonary damage markers (CC16, SP-A and SP-D) and lung function in a coke oven emission (COE) cohort with 558 coke plant workers and 210 controls. In the second stage (validation set), significant initial findings were validated by an independent diesel engine exhaust (DEE) cohort with 50 DEE exposed workers and 50 controls. Serum CC16 levels decreased in a dose response manner in association with both external and internal PM 2.5 exposures in the two cohorts. In the training set, serum CC16 levels decreased with increasing duration of occupational PM 2.5 exposure history. An interquartile range (IQR) (122.0μg/m 3 ) increase in PM 2.5 was associated with a 5.76% decrease in serum CC16 levels, whereas an IQR (1.06μmol/mol creatinine) increase in urinary 1-hydroxypyrene (1-OHP) concentration was associated with a 5.36% decrease in serum CC16 levels in the COE cohort. In the validation set, the concentration of serum CC16 in the PM 2.5 exposed group was 22.42% lower than that of the controls and an IQR (1.24μmol/mol creatinine) increase in urinary 1-OHP concentration was associated with a 12.24% decrease in serum CC16 levels in the DEE cohort. Serum CC16 levels may be a sensitive marker for pulmonary damage in populations with high PM 2.5 exposure. Copyright © 2017 Elsevier Ltd. All rights reserved.

  12. Hydraulic design of a re-circulating water cooling system of a combined cycle power plant in Thailand

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Sarkar, C.K.; Pandit, D.R.; Kwon, S.G.

    The paper describes the hydraulic design and hydraulic transient analysis of the re-circulating water cooling system of the combined cyclo Sipco power cogeneration plant in Thailand. The power plant of 450 MW total capacity is proposed to be built in two stages. Stage one will produce 300 MW of power and will consist of two gas turbine generators (GTG) and one steam turbine generator (STG). Stage two will produce 150 MW of power and will consist of one GTG and one STG. The cooling system will consist of one GTG and one STG. The cooling system will consist of coolingmore » towers, a combined collecting basin and pump intake sump, pumps and motors, and separate conveyance systems and condensers for the generator units in the two stages. In a re-circulating water cooling system, cold water is pumped from the pump intake sump to the condensers through the conveyance system and hot water from the condensers is carried through the returning pipeline system to the cooling towers, whence the water after cooling is drained into the sump at the base of the towers. Total cooling water requirement for the system in stage one is estimated to be 112,000 gallons per minute (GPM), and that in stage two, 56,000 GPM. The sump is designed using the computer program HEC-2, developed by the US Army Corps of Engineers (COE) and the pump intake basin, following the recommendations of the Hydraulic Institute. The pumps were sized by computing the head loss in the system, and, the steady state and transient performances (during pump start-up and shut-down procedures and due to possible power or mechanical failure of one or all pumps) of the system were analyzed by mathematically modeling the system using the computer program WHAMO (Water Hammer nd Mass Oscillations), also developed by the COE.« less

  13. Fractional ultrabasic-basic evolution of upper-mantle magmatism: Evidence from xenoliths in kimberlites, inclusions in diamonds and experiments

    NASA Astrophysics Data System (ADS)

    Litvin, Yuriy; Kuzyura, Anastasia

    2017-04-01

    Ultrabasic peridotites and pyroxenites together with basic eclogites are the upper-mantle in situ rocks among xenoliths in kimberlites. Occasionally their diamond-bearing varieties have revealed within the xenoliths. Therewith the compositions of rock-forming minerals demonstrate features characteristic for primary diamond-included minerals of peridotite and eclogite parageneses (the elevated contents of Cr-component in peridotitic garnets and Na-jadeitic component in eclogitic clinopyroxenes). High-pressure experimental study of melting equilibria on the multicomponent peridotie-pyroxenite system olivine Ol - orthopyroxene Opx - clinopyroxene Cpx - garnet Grt showed that Opx disappeared in the peritectic reaction Opx+L→Cpx (Litvin, 1991). As a result, the invariant peritectic equilibrium Ol+Opx+Cpx+Grt+L of the ultrabasic system was found to transform into the univariant cotectic assemblage Ol+Cpx+Grt+L. Further experimental investigation showed that olivine reacts with jadeitic component (Jd) with formation of garnet at higher 4.5 GPa (Gasparik, Litvin, 1997). Study of melting relations in the multicomponent system Ol - Cpx - Jd permits to discover the peritectic point Ol+Omph+Grt+L (where Omph - omphacitic clinopyroxene) at concentration 3-4 wt.% Jd-component in the system. The reactionary loss of Opx and Ol makes it possible to transform the 4-phase garnet lherzolite ultrabasic association into the bimineral eclogite assemblage. The regime of fractional Ol, Cpx and Grt crystallization must be accompanied by increasing content of jadeitic component in residual melts that causes the complete "garnetization of olivine". In the subsequent evolution, the melts would have to fractionate for basic SiO2-saturated compositions responsible for petrogenesis of eclogite varieties marked with accessory corundum Crn, kyanite Ky and coesite Coe. Both the peritectic mechanisms occur in regime of fractional crystallization. The sequence of the upper-mantle fractional ultrabasic-basic magmatic evolution and petrogenesis may be controlled by the following melting relations: from Ol, Opx, L field to cotectic curve Ol, Opx, Cpx, L, peritectic point Ol, Opx, Cpx, Grt, L (loss of Opx), cotectic curve Ol, (Cpx+Jd), Grt, L, peritectic point Ol, (Cpx→Omph), Grt, L (loss of Ol), divariant field Omph,Grt,L, cotectic curve Ky, Omph, Grt, L, eutectic point Ky,Coe,Omph, Grt,L, subsolidus assemblage Ky,Coe,Omph, Grt. The fractional ultrabasic-basic evolution of the upper-mantle silicate-carbonate-carbon melts-solutions, which are responsible for genesis of diamond-and-inclusions associations and diamond-bearing peridotites and eclogites, follows the similar physico-chemical mechanisms (Litvin et al., 2016). This is illustrated by fractional syngenesis diagram for diamonds and associated minerals which construction is based on evidence from high pressure experiments. References Gasparik T., Litvin Yu.A (1997). Stability of Na2Mg2Si2O7 and melting relations on the forsterite - jadeite join at pressures up to 22 GPa. Eur, J. Mineral. 9(2), 311-326. Litvin Yu.A. (1991). Physico-Chemical Study of Melting of Materials from the Deep Earth. Moscow: Nauka. 312 p. Litvin Yu.A., Spivak A.V., Kuzyura A.V. (2016). Fundamentals of the mantle-carbonatite concept of diamond genesis, Geochemistry Internat. 34(10), 839-857.

  14. Integrated underground gas storage of CO2 and CH4 to decarbonize the "power-to-gas-to-gas-to-power" technology

    NASA Astrophysics Data System (ADS)

    Kühn, Michael; Streibel, Martin; Nakaten, Natalie; Kempka, Thomas

    2014-05-01

    Massive roll-out of renewable energy production units (wind turbines and solar panels) leads to date to excess energy which cannot be consumed at the time of production. So far, long-term storage is proposed via the so called 'power-to-gas' technology. Energy is transferred to methane gas and subsequently combusted for power production - 'power-to-gas-to-power' (PGP) - when needed. PGP profits from the existing infrastructure of the gas market and could be deployed immediately. However, major shortcoming is the production of carbon dioxide (CO2) from renewables and its emission into the atmosphere. We present an innovative idea which is a decarbonised extension of the PGP technology. The concept is based on a closed carbon cycle: (1) Hydrogen (H2) is generated from renewable energy by electrolysis and (2) transformed into methane (CH4) with CO2 taken from an underground geological storage. (3) CH4 produced is stored in a second storage underground until needed and (4) combusted in a combined-cycled power plant on site. (5) CO2 is separated during energy production and re-injected into the storage formation. We studied a show case for the cities Potsdam and Brandenburg/Havel in the Federal State of Brandenburg in Germany to determine the energy demand of the entire process chain and the costs of electricity (COE) using an integrated techno-economic modelling approach (Nakaten et al. 2014). Taking all of the individual process steps into account, the calculation shows an overall efficiency of 27.7 % (Streibel et al. 2013) with total COE of 20.43 euro-cents/kWh (Kühn et al. 2013). Although the level of efficiency is lower than for pump and compressed air storage, the resulting costs are similar in magnitude, and thus competitive on the energy storage market. The great advantage of the concept proposed here is that, in contrast to previous PGP approaches, this process is climate-neutral due to CO2 utilisation. For that purpose, process CO2 is temporally stored in an underground reservoir. If existing locations in Europe, where natural gas storage in porous formations is performed, were to be extended by CO2 storage sites, a significant quantity of wind and solar energy produced could be stored as methane. The overall process chain is in this case carbon neutral. Kühn M., Nakaten N., Streibel M., Kempka T. (2013) Klimaneutrale Flexibilisierung regenerativer Überschussenergie mit Untergrundspeichern. ERDÖL ERDGAS KOHLE 129(10), 348-352. Nakaten, N., Schlüter, R., Azzam, R., Kempka, T. (2014) Development of a techno-economic model for dynamic calculation of COE, energy demand and CO2 emissions of an integrated UCG-CCS process, Energy (in press). doi: 10.1016/j.energy.2014.01.014 Streibel M., Nakaten N., Kempka T., Kühn M. (2013) Analysis of an integrated carbon cycle for storage of renewables. Energy Procedia 40, 202-211. doi: 10.1016/j.egypro.2013.08.024.

  15. 76 FR 17145 - Agency Information Collection Activities: Business Transformation-Automated Integrated Operating...

    Federal Register 2010, 2011, 2012, 2013, 2014

    2011-03-28

    ... Collection Activities: Business Transformation--Automated Integrated Operating Environment (IOE), New... Transformation--Integrated Operating Environment (IOE); OMB Control No. 1615-NEW. SUMMARY: USCIS is developing an automated Integrated Operating Environment (IOE) to process benefit applications. The IOE will collect...

  16. Early chordate origins of the vertebrate second heart field.

    PubMed

    Stolfi, Alberto; Gainous, T Blair; Young, John J; Mori, Alessandro; Levine, Michael; Christiaen, Lionel

    2010-07-30

    The vertebrate heart is formed from diverse embryonic territories, including the first and second heart fields. The second heart field (SHF) gives rise to the right ventricle and outflow tract, yet its evolutionary origins are unclear. We found that heart progenitor cells of the simple chordate Ciona intestinalis also generate precursors of the atrial siphon muscles (ASMs). These precursors express Islet and Tbx1/10, evocative of the splanchnic mesoderm that produces the lower jaw muscles and SHF of vertebrates. Evidence is presented that the transcription factor COE is a critical determinant of ASM fate. We propose that the last common ancestor of tunicates and vertebrates possessed multipotent cardiopharyngeal muscle precursors, and that their reallocation might have contributed to the emergence of the SHF.

  17. Methods of reducing energy consumption of the oxidant supply system for MHD/steam power plants

    NASA Technical Reports Server (NTRS)

    Juhasz, A. J.

    1983-01-01

    An in-depth study was conducted to identify possible improvements to the oxidant supply system for combined cycle MHD power plants which would lead to higher thermal efficiency and reduction in the cost of electricity, COE. Results showed that the oxidant system energy consumption could be minimized when the process was designed to deliver a product O2 concentration of 70 mole percent. The study also led to the development of a new air separation process, referred to as liquid pumping and internal compression. MHD system performance calculations show that the new process would permit an increase in plant thermal efficiency of 0.6 percent while allowing more favorable tradeoffs between magnetic energy and oxidant system capacity requirements.

  18. Methods of reducing energy consumption of the oxidant supply system for MHD/steam power plants

    NASA Technical Reports Server (NTRS)

    Juhasz, A. J.

    1983-01-01

    An in-depth study was conducted to identify possible improvements to the oxidant supply system for combined cycle MHD power plants which would lead to higher thermal efficiency and reduction in the cost of electricity, COE. Results showed that the oxidant system energy consumption could be minimized when the process was designed to deliver a product O2 concentration of 70 mole percent. The study also led to the development of a new air separation process, referred to as 'liquid pumping and internal compression'. MHD system performance calculations show that the new process would permit an increase in plant thermal efficiency of 0.6 percent while allowing more favorable tradeoffs between magnetic energy and oxidant system capacity requirements.

  19. Honors

    NASA Astrophysics Data System (ADS)

    2013-11-01

    The recently released list of 2013-2014 Fulbright Scholars includes 9 AGU members working on diverse topics. They include Michael Coe, senior scientist/coordinator of the Amazon group at the Woods Hole Research Center, whose topic is "Agricultural expansion in the Brazilian Cerrado and consequences for the water cycle"; Benjamin Crosby, associate professor, Department of Geosciences, Idaho State University, on the topic "Taking the pulse of Chilean rivers: Enhancing educational and academic opportunities in a time of rapid change"; David Fitzjarrald, senior research associate, Atmospheric Sciences Research Center, State University of New York at Albany, on the topic "Landscape heterogeneity and Amazonian mesoclimate: Fostering critical understanding of observations and model output"; and Syed Hasan, professor of geology, Department of Geosciences, University of Missouri-Kansas City, who will be teaching courses in waste management.

  20. Cellular senescence in the Penna model of aging

    NASA Astrophysics Data System (ADS)

    Periwal, Avikar

    2013-11-01

    Cellular senescence is thought to play a major role in age-related diseases, which cause nearly 67% of all human deaths worldwide. Recent research in mice showed that exercising mice had higher levels of telomerase, an enzyme that helps maintain telomere length, than nonexercising mice. A commonly used model for biological aging was proposed by Penna. I propose a modification of the Penna model that incorporates cellular senescence and find an analytical steady-state solution following Coe, Mao, and Cates [Phys. Rev. Lett.PRLTAO0031-900710.1103/PhysRevLett.89.288103 89, 288103 (2002)]. I find that models corresponding to delayed cellular senescence have younger populations that live longer. I fit the model to the United Kingdom's death distribution, which the original Penna model cannot do.

  1. Turbulence Spectral Widths View Angle Independence as Observed by Doppler Radar

    DTIC Science & Technology

    1989-10-01

    t, 1*+ 0 1T t+ ( 10) 2.+ 1I+. 3 3 1 9 Z1 9 1 1 21 S I 10 30 .. 1 11 30 49 3 D. 10 33 !’~3 . 02 2. F6 ’ -36 6 3 6 5 so 6 6 31 If., 68r t+.+ I’. . . .I... ACCA . .. AbA Co. CA•,A~ ... . ... C . .* CC~ CC C .... AC ... C . AC... CC CC . . . .. AAA C A 52CCC.CCCC A C AC. 51. CC 37. A. CACC C Cb...coeCcients b t e. and CCC ’l C. ..... .. o. oCA . .... °AACAA CC * C ... C 12.)0 35. 39. ’.. ’.5. A.. 37. 51 . 18. A• ACCA CCCCCCCCCCCCCCCCCCCCCC

  2. Multidisciplinary Design Optimization for Glass-Fiber Epoxy-Matrix Composite 5 MW Horizontal-Axis Wind-Turbine Blades

    NASA Astrophysics Data System (ADS)

    Grujicic, M.; Arakere, G.; Pandurangan, B.; Sellappan, V.; Vallejo, A.; Ozen, M.

    2010-11-01

    A multi-disciplinary design-optimization procedure has been introduced and used for the development of cost-effective glass-fiber reinforced epoxy-matrix composite 5 MW horizontal-axis wind-turbine (HAWT) blades. The turbine-blade cost-effectiveness has been defined using the cost of energy (CoE), i.e., a ratio of the three-blade HAWT rotor development/fabrication cost and the associated annual energy production. To assess the annual energy production as a function of the blade design and operating conditions, an aerodynamics-based computational analysis had to be employed. As far as the turbine blade cost is concerned, it is assessed for a given aerodynamic design by separately computing the blade mass and the associated blade-mass/size-dependent production cost. For each aerodynamic design analyzed, a structural finite element-based and a post-processing life-cycle assessment analyses were employed in order to determine a minimal blade mass which ensures that the functional requirements pertaining to the quasi-static strength of the blade, fatigue-controlled blade durability and blade stiffness are satisfied. To determine the turbine-blade production cost (for the currently prevailing fabrication process, the wet lay-up) available data regarding the industry manufacturing experience were combined with the attendant blade mass, surface area, and the duration of the assumed production run. The work clearly revealed the challenges associated with simultaneously satisfying the strength, durability and stiffness requirements while maintaining a high level of wind-energy capture efficiency and a lower production cost.

  3. Performance Analysis of Solar-Wind-Diesel-Battery Hybrid Energy System for KLIA Sepang Station of Malaysia

    NASA Astrophysics Data System (ADS)

    Shezan, S. K. A.; Saidur, R.; Hossain, A.; Chong, W. T.; Kibria, M. A.

    2015-09-01

    A large number of populations of the world live in rural or remote areas those are geographically isolated. Power supply and uninterrupted fuel transportation to produce electrical power for these remote areas poses a great challenge. Using renewable energy in hybrid energy system might be a pathway to solve this problem. Malaysia is a large hilly land with the gift of renewable energy resources. There is a good chance to utilize these renewable resources to produce electrical power and to limit the dependency on the fossil fuel as well as reduce the carbon emissions. In this perspective, a research is carried out to analyze the performance of a solar-wind-diesel-battery hybrid energy system for a remote area named “KLIA Sepang station” in the state of Selangor, Malaysia. In this study, a 56 kW hybrid energy system has been proposed that is capable to support more than 50 households and 6 shops in that area. Real time field data of solar radiation and wind speed is used for the simulation and optimization of operations using “Homer” renewable energy software. The proposed system can reduce CO2 emission by about 16 tons per year compared to diesel generator only. In the same time the Cost of energy (COE) of the optimized system is USD 5.126/kWh.The proposed hybrid energy system might be applicable for other parts of the world where the climate conditions are similar.

  4. Measuring Command Post Operations in a Decisive Action Training Environment

    DTIC Science & Technology

    2017-05-01

    Research Report 2001 Measuring Command Post Operations in a Decisive Action Training Environment Michelle N...September 2014 - September 2015 4. TITLE AND SUBTITLE Measuring Command Post Operations in a Decisive Action Training Environment 5a...Readiness Training Center Warrior Leadership Council, we explored whether a guide on Command Post (CP) Operations could improve performance during

  5. A review of the Fukushima nuclear reactor accident: radiation effects on the thyroid and strategies for prevention.

    PubMed

    Nagataki, Shigenobu; Takamura, Noboru

    2014-10-01

    This is a summary of the nuclear accident at the Tokyo Electric Power Company Fukushima Daiichi Nuclear Power Stations (FDNPS) on 11 March 2011 to be used as a review of the radiation effects to the thyroid and strategies of prevention. The amount of radioiodine released to the environment following the Fukushima accident was 120 Peta Becquerel, which is approximately one-tenth of that in the Chernobyl accident. Residents near the FDNPS were evacuated within a few days and foodstuffs were controlled within 1 or 2 weeks. Therefore, thyroid radiation doses were less than 100 mSv (intervention levels for stable iodine administration) in the majority of children, including less than 1 year olds, living in the evacuation areas. Because the incidence of childhood thyroid cancer increased in those residing near the site following the Chernobyl accident, thyroid screening of all children (0-18 years old) in the Fukushima Prefecture was started. To date, screening of more than 280 000 children has resulted in the diagnosis of thyroid cancer in 90 children (approximate incidence, 313 per million). Thus, although the dose of radiation was much lower, the incidence of thyroid cancer appears to be much higher than that following the Chernobyl accident. A comparison of the thyroidal consequences following the Fukushima and Chernobyl nuclear reactor accidents is discussed. We also summarize the recent increased incidence in thyroid cancer in the Fukushima area following the accident in relation to increased thyroid ultrasound screening and the use of advanced ultrasound techniques. http://links.lww.com/COE/A8.

  6. Principles of a clean operating room environment.

    PubMed

    Howard, James L; Hanssen, Arlen D

    2007-10-01

    Optimizing the operating room environment is necessary to minimize the prevalence of arthroplasty infection. Reduction of bacterial contamination in the operating room should be a primary focus of all members of the operating room team. However, in recent years, there has been a decline in the emphasis of the basic principles of antisepsis in many operating rooms. The purpose of this review is to highlight important considerations for optimizing the operating room environment. These principles should be actively promoted by orthopedic surgeons in their operating rooms as part of a comprehensive approach to minimizing arthroplasty infection.

  7. Human Machine Interfaces for Teleoperators and Virtual Environments Conference

    NASA Technical Reports Server (NTRS)

    1990-01-01

    In a teleoperator system the human operator senses, moves within, and operates upon a remote or hazardous environment by means of a slave mechanism (a mechanism often referred to as a teleoperator). In a virtual environment system the interactive human machine interface is retained but the slave mechanism and its environment are replaced by a computer simulation. Video is replaced by computer graphics. The auditory and force sensations imparted to the human operator are similarly computer generated. In contrast to a teleoperator system, where the purpose is to extend the operator's sensorimotor system in a manner that facilitates exploration and manipulation of the physical environment, in a virtual environment system, the purpose is to train, inform, alter, or study the human operator to modify the state of the computer and the information environment. A major application in which the human operator is the target is that of flight simulation. Although flight simulators have been around for more than a decade, they had little impact outside aviation presumably because the application was so specialized and so expensive.

  8. Analysis of wind energy potential for agriculture pump in mountain area Aceh Besar

    NASA Astrophysics Data System (ADS)

    Syuhada, Ahmad; Maulana, Muhammad Ilham; Fuadi, Zahrul

    2017-06-01

    In this study, the potential of wind power for agricultural pump driver in Saree mountainous area of Aceh Besar is analyzed. It is found that the average usable wind speed is 6.41 m/s, which is potential to produce 893.96 Watt of electricity with the wind turbine rotor diameter of 3 m. This energy can be used to drive up to 614 Watt of water pump with static head of 20 m to irrigate 19 hectare of land, 7 hours a day. HOMER analysis indicated the lowest simulated NPC value of USD 10.028 with CoE of USD 0.717 kWh. It is also indicated that the wind has potential to produce 3452 kWh/year with lifetime of 15 years.

  9. European regulations and their impact on tissue banking.

    PubMed

    Tatarenko, Alina

    2006-01-01

    Extensive CoE-EU cooperation ensures coherence and complementarities between the principles of the CoE guides which can be regarded as recommendations on best practice, and the technical requirements of the EU directives which set out legally binding requirements. This means that the same standards now exist throughout European continent. Having a common set of standards facilitates cooperation between different healthcare systems, especially in cases of emergencies, and the export-import issues. Adoption of the same quality management and traceability systems helps to minimise the risks and prevent disease transmissions. It reassures patients who undergo treatments outside of their countries. The tissue establishments need to introduce technical and structural changes to adhere to the new regulations which ultimately results in saving and improving of lives of many patients.

  10. Wave drag reduction with a self-aligning aerodisk on a missile configuration

    NASA Astrophysics Data System (ADS)

    Schnepf, C.; Wysocki, O.; Schülein, E.

    2017-06-01

    A self-aligning aerodisk to reduce the wave drag on a pitching missile is numerically investigated. The motion and the Mach number were chosen to match a maneuver flight of an actual missile: pitching frequency f = 7.5 Hz, Mach number M = 2.2, and range of angle of attack 0° < < 21° . The self-alignment was realized with a coupling of the §ow solver with a 6DoF (6 degrees of freedom) tool. In the entire range of angle of attack, the drag could be reduced with the self-aligning aerodisk. A comparison with experimental data showed in parts a quite good agreement in the aerodynamic coe©cients, in the shock structure, and in the alignment of the aerodisk.

  11. The Data Base for the May 1979 Marine Surface Layer Micrometeorological Experiment at San Nicolas Island, California.

    DTIC Science & Technology

    1982-05-07

    ATIO VE LOC I TY HUMIDITY TEMP. L ENGTH ClIFF. 72% 7TO 160 4% 53% IS 5% A8t RZ lit 492 29% 23% END Of DATA RIiM 29 MARINE SURFACE LAYER...DRAG NO.AT GMM AlTOIM FL UX FLUX FLUX FL UX FLU X RTATIO VK LOC ITTY HUtMIDITY TEMP. LEN4GTH COE. 160% 161% 116% 167% 128% 9% 124% 295% s8% 109% 71...SCC PSI 90951!4 DRAG; NT, VT "MXT ’tI TIM ELS L X H Sy I 1(09rU F LT PtX ATIO VE LOC ITY ((IIDITIY TE MP. L EM!.TIH ItF 11% (1, .14% Il 195 Tx 5% 2A

  12. Concept of Operations for Commercial and Business Aircraft Synthetic Vision Systems. 1.0

    NASA Technical Reports Server (NTRS)

    Williams Daniel M.; Waller, Marvin C.; Koelling, John H.; Burdette, Daniel W.; Capron, William R.; Barry, John S.; Gifford, Richard B.; Doyle, Thomas M.

    2001-01-01

    A concept of operations (CONOPS) for the Commercial and Business (CaB) aircraft synthetic vision systems (SVS) is described. The CaB SVS is expected to provide increased safety and operational benefits in normal and low visibility conditions. Providing operational benefits will promote SVS implementation in the Net, improve aviation safety, and assist in meeting the national aviation safety goal. SVS will enhance safety and enable consistent gate-to-gate aircraft operations in normal and low visibility conditions. The goal for developing SVS is to support operational minima as low as Category 3b in a variety of environments. For departure and ground operations, the SVS goal is to enable operations with a runway visual range of 300 feet. The system is an integrated display concept that provides a virtual visual environment. The SVS virtual visual environment is composed of three components: an enhanced intuitive view of the flight environment, hazard and obstacle defection and display, and precision navigation guidance. The virtual visual environment will support enhanced operations procedures during all phases of flight - ground operations, departure, en route, and arrival. The applications selected for emphasis in this document include low visibility departures and arrivals including parallel runway operations, and low visibility airport surface operations. These particular applications were selected because of significant potential benefits afforded by SVS.

  13. Detachment 101 and North Burma: Historical Conditions for Future Unconventional Warfare Operations

    DTIC Science & Technology

    2016-05-26

    s area of operations and one of the most austere and unforgiving environments, delivers numerous examples of how the physical environment can create...achieve success under challenging conditions, with limited resources.15 As one of the most austere and unforgiving operational environments, north Burma

  14. Admissions to hospital with exacerbations of chronic obstructive pulmonary disease: Effect of age related factors and service organisation.

    PubMed

    Connolly, M J; Lowe, D; Anstey, K; Hosker, H S R; Pearson, M G; Roberts, C M

    2006-10-01

    Exacerbations of chronic obstructive pulmonary disease (COPD) have a high rate of mortality which gets worse with advancing age. It is unknown whether this is due to age related deficiencies in process of care. A study was undertaken in patients with COPD exacerbations admitted to UK hospitals to assess whether there were age related differences in the process of care that might affect outcome, and whether different models of care affected process and outcome. 247 hospital units audited activity and outcomes (inpatient death, death within 90 days, length of stay (LOS), readmission within 90 days) for 40 consecutive COPD exacerbation admissions in autumn 2003. Logistic regression methods were used to assess relationships between process and outcome at p < 0.001. 7514 patients (36% aged > or = 75 years) were included. Patients aged > or = 75 years were less likely to have blood gases documented, to have FEV1 recorded, or to be given systemic corticosteroids. Those admitted under care of the elderly (CoE) physicians were less likely to enter early discharge schemes or to receive non-invasive ventilation when acidotic. Overall inpatient and 90 day mortality was 7.4% and 15.3%, respectively. Inpatient and 90 day adjusted odds mortality rates for those aged > or = 85 years (versus < or = 65 years) were 3.25 and 2.54, respectively. Mortality was unaffected by admitting physician (CoE v general v respiratory). Age predicted LOS but not readmission. Age related deficiencies in process of care did not predict inpatient or 90 day mortality, readmission, or LOS. Management of COPD exacerbations varies with age in UK hospitals. Inpatient and 90 day mortality is approximately three times higher in very elderly patients with a COPD exacerbation than in younger patients. Age related deficiencies in the process of care were not associated with mortality, but it is likely that they represent poorer quality of care and patient experience. Recommended standards of care should be applied equally to elderly patients with an exacerbation of COPD.

  15. Mission Planning for Heterogeneous UxVs Operating in a Post-Disaster Urban Environment

    DTIC Science & Technology

    2017-09-01

    FOR HETEROGENEOUS UxVs OPERATING IN A POST -DISASTER URBAN ENVIRONMENT by Choon Seng Leon Mark Tan September 2017 Thesis Advisor: Oleg...September 2017 3. REPORT TYPE AND DATES COVERED Master’s thesis 4. TITLE AND SUBTITLE MISSION PLANNING FOR HETEROGENEOUS UxVs OPERATING IN A POST ...UxVs OPERATING IN A POST -DISASTER URBAN ENVIRONMENT Choon Seng Leon Mark Tan Civilian Engineer, ST Aerospace Ltd., Singapore B. Eng (Hons

  16. PREFACE: First International Workshop on Nonequilibrium Processes in Plasma Physics and Studies of Environment

    NASA Astrophysics Data System (ADS)

    Petrović, Z. Lj; Malović, G.; Tasić, M.; Nikitović, Ž.

    2007-06-01

    This volume is a collection of papers associated with a series of invited lectures presented at the First Workshop on Nonequilibrium processes in Plasma Physics and studies of Environment that was held at Mt Kopaonik in August 2006. The workshop originated as a part of the FP6 COE 026328 which had the basic aim of promoting centers of excellence in Western Balkan countries, to facilitate dissemination of their results and to help them establish themselves in the broader arena of European and international science. So the best way to achieve all those goals was to prepare a workshop associated with the local conference SPIG (Symposium on Physics of Ionized Gases) where the participants could attend sessions in which the host Laboratory presented progress reports and papers and thereby gain a full perspective of our results. At the same time this allowed participants in the COE the opportunity to compare their results with the results of external speakers and to gain new perspectives and knowledge. The program of the workshop was augmented by inviting some of our colleagues who visited the COE in recent years or have an active collaboration with a participating member. In that respect this volume is not only a proceedings of the workshop but a collection of papers related to the topic of the workshop: Non-equilibrium phenomena in plasmas and in the science of our environment. The idea is to offer review articles either summarizing a broader area of published or about to be published work or to give overviews showing preliminary results of the works in progress. The refereeing of the papers consisted of two parts, first in selection of the invitees and second in checking the submitted manuscripts. The papers were refereed to the standard of the Journal. As the program of the COE covers a wide area of topics from application of plasmas in nano- electronics to monitoring and removal of pollutants in the atmosphere, so the program of the workshop covered an even broader range of topics with the common thread of non- equilibrium phenomena playing a major part in the basic physics and also in the technological applications. The universal symbol of non-equilibrium phenomena is Maxwell's demon and it was selected, as designed by Professor Rastko Ćirić (of Belgrade's University for Fine Arts), to be the symbol of the conference. In plasma physics, the field is usually divided between equilibrium and non-equilibrium plasmas. The advantage of studying plasmas in thermal equilibrium is that they may be described by universal laws, such as Saha and Boltzmann equations. The only problem is that, apart from the very early stages in the development of the universe, such plasmas do not exist, although there are plasmas that come very close and at least satisfy the thermal laws locally. Non-equilibrium plasmas have laws unique to each situation and studies of their idiosyncrasies continue to provide a lot of food for thought for scientists, possibilities for applications and job opportunities. Or as Tolstoy wrote, `Happy families are all alike; every unhappy family is unhappy in its own way?'. So, while making analogy of the non-equilibrium with the lack of happiness may sound discouraging, the scientists who try to observe these phenomena (like psychologists in the case of families) have plenty to study and are, therefore, likely to be happy. At the same time non-equilibrium phenomena in plasmas and in the atmosphere are extremely important. A fact we should be aware of every time we use an integrated circuit manufactured after the late 1970s or whenever weather changes, wind blows and pollution is carried in from some distant locations. This volume starts with a paper by D Batani (Milano, Italy) on shock waves, an example of plasmas that may be locally thermal but display very strong gradients, M Pinheiro (Lisboa, Portugal) contributed an article on anomalous diffusion in magnetized plasmas, a problem that has been addressed in the literature from many different standpoints. A special case of non-equilibrium is that of non-neutral plasmas, i.e. plasmas devoid of ions, as described in the lecture and paper by J Marler (Appleton, USA). Physics of swarms (the low space charge limit of ionized gases) is similar to the previous study in the fact that we may have only one group of charged particles electrons (or ions). But the difference is that the latter has a much higher pressure and therefore number of collisions. In the lecture on one aspect of the application of swarm data (transport coefficients) to determine the electron scattering cross sections R White (Townsville, Australia) addresses a long standing controversy in the vibrational excitation of H2 of an unacceptable discrepancy between swarm results and binary collision experiments and theories, (a problem that has been of particular importance to the host Laboratory). The lecture of N Dyatko (Troitsk, Russian Federation) tackles one of the most interesting recent problems in the transport theory of ionized gases, that of the negative absolute conductivity and attempts to translate it to solid state physics where the stakes are much higher. The swarm studies were always based on excellent experimental data and the leading experimental group today is that of J de Urquijo (Cuernavaca, Mexico) who presents a review of a wide range of transport data that his group obtained in fluorinated gases. The gas breakdown in dc and high frequency fields was addressed by M Radmilović-Rađenović (Belgrade, Serbia) by applying a detailed secondary electron production model in Particle in Cell (PIC) code and comparing the results to a broad range of experimental data. The hybrid (fluid-Monte Carlo) model has been applied in the study by Z Donko and K Kutasi (Budapest, Hungary) of low pressure obstructed glow discharges to decribe the effect of fast neutrals on gas discharges. A study of kinetics of negative ions of hydrogen in glow discharges with positive column and in hollow cathode dicharges is presented by R Djulgerova (Sofia, Boulgaria). Modelling and experimental results for surface plasmas with an aim to study the kinetics of dissociation are given by V Guerra (Lisboa, Portugal). L Campbell (Adelaide, Australia) describes modelling of a similar kinetics, albeit for a significantly larger ionized gas in his study of electron induced processes in the upper atmosphere. Atmospheric pressure discharges is also the topic of the work of T Gans (Belfast, Northern Ireland andBochum, Germany) but his experiments with atmospheric plasma jet are carried out at sea level and therefore the pressures are significantly higher than those for usual non-equilibrium plasmas. Higher still are the densities in plasmas generated in liquids (for medical purposes) as described in the paper of W Graham (Belfast, Northern Ireland). Another very applied aspect of non-equilibrium plasma is highlighted in a comprehensive review given by S Radovanov (Gloucester, USA) of the basic physics of the non-equilibrium plasma source for implantation of boron (for doping in the manufacture of integrated circuits) . A topical review of diagnostics of dusty particles in rf plasmas is given by I Stefanović, J Winter and colleagues (Bochum, Germany) and includes implications for plasma processing, nanotechnologies and all the way to astrophysics. Transport of particles of similar sizes in the atmosphere and its influence on the pollution of the human environment is presented in the paper by M Tasić (Belgrade, Serbia). Finally a paper that connects both aspects of the workshop, plasma physics and environment, is the review of M Radetić (Belgrade, Serbia) which covers application of low pressure non-equilibrium plasmas in treatment of textiles, not only to reduce the cost and environmental impact of the technology but also to produce filters to purify waters used in the process and in general. The broad range of topics indicates that modern plasma physics is driven not only by the need to further understand the fundamental principles but with an eye towards applications. Consequently in addition to furthering the cause of physics, we strive to improve increasingly complex technologies or develop new technologies. The non-equilibrium nature of plasmas that are the subject of our studies allows us to control properties that are critical and to design optimum conditions for these varied applications. We hope that this volume will serve as a useful source of information for experienced researchers, as a textbook for postgraduate students and as a reminder, for all who attended the workshop, of the wonderful time (http://www.euj07.phy.bg.ac.yu/index.php?page=p04) we had on top of the mountain Kopaonik, even though we were subjected to freezing temperatures in the middle of summer. Organization of this workshop was supported by INCO EU FP6 026328 project (Reinforcing Experimental Center for Non-equilibrium studies with Application in Nano-technologies, Etching of Integrated Circuits and Environmental Research), by the Ministry of Science and Environment of Serbia (project 141025) and also, to a great extend, by the individual funding of the participants some of whom traveled from remote continents in order to participate. Z Lj Petrović, G Malović, M Tasić and Ž Nikitović Editors

  17. Contaminant ions and waves in the space station environment

    NASA Technical Reports Server (NTRS)

    Murphy, G. B.

    1988-01-01

    The probable plasma (ions and electrons) and plasma wave environment that will exist in the vicinity of the Space Station and how this environment may affect the operation of proposed experiments are discussed. Differences between quiescent operational periods and non-operational periods are also addressed. Areas which need further work are identified and a course of action suggested.

  18. The 1980 Aircraft Safety and Operating Problems, part 1

    NASA Technical Reports Server (NTRS)

    Stickle, J. W. (Compiler)

    1981-01-01

    It is difficult to categorize aircraft operating problems, human factors and safety. Much of NASA's research involves all three and considers the important inter-relationships between man, the machine and the environment, whether the environment be man-made or natural. Topics covered in 20 papers include terminal-area operations; avionics and human factors; and the atmospheric environment.

  19. Overpopulated, Underdeveloped Urban Agglomerations: Tomorrow’s Unstable Operating Environment

    DTIC Science & Technology

    2012-05-08

    DATES COVERED (From - To) 4. TITLE AND SUBTITLE Overpopulated , Underdeveloped Urban Agglomerations: Tomorrow’s 5a. CONTRACT NUMBER...ABSTRACT This paper asserts that a unique future operational environment is developing: overpopulated , underdeveloped urban agglomerations. A...proposed definition for this operating environment is (or would be) an overpopulated urban area which is located within a developing or underdeveloped

  20. An evaluation of grease type ball bearing lubricants operating in various environments

    NASA Technical Reports Server (NTRS)

    Mcmurtrey, E. L.

    1981-01-01

    Because many future spacecraft or space stations will require mechanisms to operate for long periods of time in environments which are adverse to most bearing lubricants, a series of tests is continuing to evaluate 38 grease type lubricants in R-4 size bearings in five different environments for a 1 year period. Four repetitions of each test are made to provide statistical samples. These tests were used to select four lubricants for 5 year tests in selected environments with five repetitions of each test for statistical samples. At the present time, 100 test sets are completed and 22 test sets are underway. Three 5 year tests were started in (1) continuous operation and (2) start-stop operation, with both in vacuum at ambient temperatures, and (3) continuous operation at 93.3 C. In the 1 year tests the best results to date in all environments were obtained with a high viscosity index perfluoroalkylpolyether (PFPE) grease.

  1. Artificial intelligence in a mission operations and satellite test environment

    NASA Technical Reports Server (NTRS)

    Busse, Carl

    1988-01-01

    A Generic Mission Operations System using Expert System technology to demonstrate the potential of Artificial Intelligence (AI) automated monitor and control functions in a Mission Operations and Satellite Test environment will be developed at the National Aeronautics and Space Administration (NASA) Jet Propulsion Laboratory (JPL). Expert system techniques in a real time operation environment are being studied and applied to science and engineering data processing. Advanced decommutation schemes and intelligent display technology will be examined to develop imaginative improvements in rapid interpretation and distribution of information. The Generic Payload Operations Control Center (GPOCC) will demonstrate improved data handling accuracy, flexibility, and responsiveness in a complex mission environment. The ultimate goal is to automate repetitious mission operations, instrument, and satellite test functions by the applications of expert system technology and artificial intelligence resources and to enhance the level of man-machine sophistication.

  2. Space Environments and Effects Concept: Transitioning Research to Operations and Applications

    NASA Technical Reports Server (NTRS)

    Edwards, David L.; Spann, James; Burns, Howard D.; Schumacher, Dan

    2012-01-01

    The National Aeronautics and Space Administration (NASA) is embarking on a course to expand human presence beyond Low Earth Orbit (LEO) while expanding its mission to explore the solar system. Destinations such as Near Earth Asteroids (NEA), Mars and its moons, and the outer planets are but a few of the mission targets. NASA has established numerous offices specializing in specific space environments disciplines that will serve to enable these missions. To complement these existing discipline offices, a concept focusing on the development of space environment and effects application is presented. This includes space climate, space weather, and natural and induced space environments. This space environment and effects application is composed of 4 topic areas; characterization and modeling, engineering effects, prediction and operation, and mitigation and avoidance. These topic areas are briefly described below. Characterization and modeling of space environments will primarily focus on utilization during Program mission concept, planning, and design phases. Engineering effects includes materials testing and flight experiments producing data to be used in mission planning and design phases. Prediction and operation pulls data from existing sources into decision-making tools and empirical data sets to be used during the operational phase of a mission. Mitigation and avoidance will develop techniques and strategies used in the design and operations phases of the mission. The goal of this space environment and effects application is to develop decision-making tools and engineering products to support the mission phases of mission concept through operations by focusing on transitioning research to operations. Products generated by this space environments and effects application are suitable for use in anomaly investigations. This paper will outline the four topic areas, describe the need, and discuss an organizational structure for this space environments and effects application.

  3. 45 CFR 153.700 - Distributed data environment.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 45 Public Welfare 1 2013-10-01 2013-10-01 false Distributed data environment. 153.700 Section 153... Distributed Data Collection for HHS-Operated Programs § 153.700 Distributed data environment. (a) Dedicated distributed data environments. For each benefit year in which HHS operates the risk adjustment or reinsurance...

  4. 45 CFR 153.700 - Distributed data environment.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 45 Public Welfare 1 2014-10-01 2014-10-01 false Distributed data environment. 153.700 Section 153... Distributed Data Collection for HHS-Operated Programs § 153.700 Distributed data environment. (a) Dedicated distributed data environments. For each benefit year in which HHS operates the risk adjustment or reinsurance...

  5. Paleointensity determination on Neoarchaean dikes within the Vodlozerskii terrane of the Karelian craton

    NASA Astrophysics Data System (ADS)

    Shcherbakova, V. V.; Lubnina, N. V.; Shcherbakov, V. P.; Zhidkov, G. V.; Tsel'movich, V. A.

    2017-09-01

    The results of paleomagnetic studies and paleointensity determinations from two Neoarchaean Shala dikes with an age of 2504 Ma, located within the Vodlozerskii terrane of the Karelian craton, are presented. The characteristic components of primary magnetization with shallow inclinations I = -5.7 and 1.9 are revealed; the reliability of the determinations is supported by two contact tests. High paleointensity values are obtained by the Thellier-Coe and Wilson techniques. The calculated values of the virtual dipole moment (11.5 and 13.8) × 1022 A m2 are noticeably higher than the present value of 7.8 × 1022 A m2. Our results, in combination with the previous data presented in the world database, support the hypothesized existence of a period of high paleointensity in the Late Archaean-Early Proterozoic.

  6. Updated archaeointensity dataset from the SW Pacific

    NASA Astrophysics Data System (ADS)

    Hill, Mimi; Nilsson, Andreas; Holme, Richard; Hurst, Elliot; Turner, Gillian; Herries, Andy; Sheppard, Peter

    2016-04-01

    It is well known that there are far more archaeomagnetic data from the Northern Hemisphere than from the Southern. Here we present a compilation of archaeointensity data from the SW Pacific region covering the past 3000 years. The results have primarily been obtained from a collection of ceramics from the SW Pacific Islands including Fiji, Tonga, Papua New Guinea, New Caledonia and Vanuatu. In addition we present results obtained from heated clay balls from Australia. The microwave method has predominantly been used with a variety of experimental protocols including IZZI and Coe variants. Standard Thellier archaeointensity experiments using the IZZI protocol have also been carried out on selected samples. The dataset is compared to regional predictions from current global geomagnetic field models, and the influence of the new data on constraining the pfm9k family of global geomagnetic field models is explored.

  7. Economic challenges of hybrid microgrid: An analysis and approaches for rural electrification

    NASA Astrophysics Data System (ADS)

    Habibullah, Mohammad; Mahmud, Khizir; Koçar, Günnur; Islam, A. K. M. Sadrul; Salehin, Sayedus

    2017-06-01

    This paper focuses on the integration of three renewable resources: biogas, wind energy and solar energy, utilizing solar PV panels, a biogas generator, and a wind turbine, respectively, to analyze the technical and economic challenges of a hybrid micro-gird. The integration of these sources has been analyzed and optimized based on realistic data for a real location. Different combinations of these sources have been analyzed to find out the optimized combination based on the efficiency and the minimum cost of electricity (COE). Wind and solar energy are considered as the primary sources of power generation during off-peak hours, and any excess power is used to charge a battery bank. During peak hours, biogas generators produce power to support the additional demand. A business strategy to implement the integrated optimized system in rural areas is discussed.

  8. Relative Advantages of Direct and Indirect Drive for an Inertial Fusion Energy Power Plant Driven by a Diode-Pumped Solid-State Laser

    NASA Astrophysics Data System (ADS)

    Orth, C. D.

    2001-03-01

    This paper reviews our current understanding of the relative advantages of direct drive (DD) and indirect drive (ID) for a 1 GWe inertial fusion energy (IFE) power plant driven by a diode-pumped solid-state laser (DPSSL). This comparison is motivated by a recent study (1) that shows that the projected cost of electricity (COE) for DD is actually about the same as that for ID even though the target gain for DD can be much larger. We can therefore no longer assume that DD is the ultimate targeting scenario for IFE, and must begin a more rigorous comparison of these two drive options. The comparison begun here shows that ID may actually end up being preferred, but the uncertainties are still rather large.

  9. 40 CFR 265.254 - Design and operating requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 26 2011-07-01 2011-07-01 false Design and operating requirements. 265.254 Section 265.254 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES... DISPOSAL FACILITIES Waste Piles § 265.254 Design and operating requirements. The owner or operator of each...

  10. 40 CFR 64.7 - Operation of approved monitoring.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Operation of approved monitoring. 64.7 Section 64.7 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) COMPLIANCE ASSURANCE MONITORING § 64.7 Operation of approved monitoring. (a) Commencement of operation. The...

  11. Investigating the Feasibility of Conducting Human Tracking and Following in an Indoor Environment Using a Microsoft Kinect and the Robot Operating System

    DTIC Science & Technology

    2017-06-01

    implement human following on a mobile robot in an indoor environment . B. FUTURE WORK Future work that could be conducted in the realm of this thesis...FEASIBILITY OF CONDUCTING HUMAN TRACKING AND FOLLOWING IN AN INDOOR ENVIRONMENT USING A MICROSOFT KINECT AND THE ROBOT OPERATING SYSTEM by...FEASIBILITY OF CONDUCTING HUMAN TRACKING AND FOLLOWING IN AN INDOOR ENVIRONMENT USING A MICROSOFT KINECT AND THE ROBOT OPERATING SYSTEM 5. FUNDING NUMBERS

  12. Future Naval Training Environments

    DTIC Science & Technology

    2002-11-01

    as essential for creating a realistic training environment and for emotional conditioning of sailors and Marines. As our Senior Study Group observed...specific responsibilities, and the aspects of the real-world operational environment that required emotional condi- tioning. Assess support of training...of current training environments as compared to the actual operational environments . We will then explore the concept of emotional conditioning and how

  13. 17 CFR 240.17Ad-21T - Operational capability in a Year 2000 environment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Operational capability in a Year 2000 environment. 240.17Ad-21T Section 240.17Ad-21T Commodity and Securities Exchanges SECURITIES... Company Rules § 240.17Ad-21T Operational capability in a Year 2000 environment. (a) This section applies...

  14. Infantry Small-Unit Mountain Operations

    DTIC Science & Technology

    2011-02-01

    expended to traverse it.  Unique sustainment solutions. Sustainment in a mountain environment is a challenging and time-consuming process . Terrain...a particular environment during the intelligence preparation of the battlefield (IPB) process and provide the analysis to the company. The IPB...consists of a four-step process that includes—  Defining the operational environment.  Describing environmental effects on operations.  Evaluating the

  15. An evaluation of grease type ball bearing lubricants operating in various environments

    NASA Technical Reports Server (NTRS)

    Mcmurtrey, E. L.

    1979-01-01

    Grease type lubricants in bearings were evaluated in five different adverse environments for a one year period. Four repetitions of each test were made to provide statistical samples. These tests were then used to select four lubricants for five year tests in selected environments with five repetitions of each test for statistical samples. Three five year tests were started in (1) continuous operation; (2) start-stop operation, with both in vacuum at ambient temperatures; and (3) continuous operation at 93.3 C. To date, in the one year tests, the best results in all environments were obtained with a high viscosity index perfluoroalkylpolyether grease.

  16. 40 CFR 60.2944 - What operating parameter monitoring equipment must I install, and what operating parameters must...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 6 2011-07-01 2011-07-01 false What operating parameter monitoring equipment must I install, and what operating parameters must I monitor? 60.2944 Section 60.2944 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Operator...

  17. Scientific Hybrid Realtiy Environments (SHyRE): Bringing Field Work into the Laboratory

    NASA Technical Reports Server (NTRS)

    Miller, M. J.; Graff, T.; Young, K.; Coan, D.; Whelley, P.; Richardson, J.; Knudson, C.; Bleacher, J.; Garry, W. B.; Delgado, F.; hide

    2018-01-01

    The use of analog environments in preparing for future planetary surface exploration is key in ensuring we both understand the processes shaping other planetary surfaces as well as develop the technology, systems, and concepts of operations necessary to operate in these geologic environments. While conducting fieldwork and testing technology in relevant terrestrial field environments is crucial in this development, it is often the case that operational testing requires a time-intensive iterative process that is hampered by the rigorous conditions (e.g. terrain, weather, location, etc.) found in most field environments. Additionally, field deployments can be costly and must be scheduled months in advance, therefore limiting the testing opportunities required to investigate and compare science operational concepts to only once or twice per year.

  18. Multiple operating system rotation environment moving target defense

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Evans, Nathaniel; Thompson, Michael

    Systems and methods for providing a multiple operating system rotation environment ("MORE") moving target defense ("MTD") computing system are described. The MORE-MTD system provides enhanced computer system security through a rotation of multiple operating systems. The MORE-MTD system increases attacker uncertainty, increases the cost of attacking the system, reduces the likelihood of an attacker locating a vulnerability, and reduces the exposure time of any located vulnerability. The MORE-MTD environment is effectuated by rotation of the operating systems at a given interval. The rotating operating systems create a consistently changing attack surface for remote attackers.

  19. Food quality regulates the metabolism and reproduction of Temora longicornis

    NASA Astrophysics Data System (ADS)

    Nobili, R.; Robinson, C.; Buitenhuis, E.; Castellani, C.

    2013-02-01

    A laboratory study was undertaken to determine the effect of food quality on feeding, respiration, reproduction and the resulting carbon budget of Temora longicornis. The stoichiometric ratios N : P, C : N and C : P of Rhodomonas salina were used as indicators of food quality. R. salina was grown in media with different inorganic nutrient concentrations to produce food for T. longicornis with particulate organic N : P ratios ranging from 10 : 1 to 23 : 1. Feeding rate was not affected by food quality. Maximum respiration (R), egg production rate (EPR), assimilation efficiency (AE), gross growth efficiency (GGE) and metabolic increment (MI) occurred when T. longicornis was fed on phytoplankton with a food quality of 16N : 1P. EPR, GGE and AE also decreased with decreasing C : N ratio and the energy required to produce eggs (CoE) decreased with decreasing N : P ratio, indicative of nitrogen-dependent production. These data suggest that an algal composition of 16N : 1P defines the Threshold Elemental Ratio (TER) and is the optimum diet for T. longicornis. The variations in metabolic rates and the resulting carbon budget are proportional to the quality of food ingested. GGE was negatively affected at dietary ratios above and below 16N : 1P, which in the natural environment could lead to a decline in species biomass with detrimental consequences for fisheries and carbon export. Field data show that phytoplankton organic N : P ratios can change on decadal timescales, and that an increase in the food N : P ratio can co-occur with a shift to smaller sized zooplankton and a change in species abundance. Further research is required to assess how much of the change in zooplankton community structure and activity can be attributed to changes in food quality, rather than to changes in temperature and food quantity.

  20. 17 CFR 240.15b7-3T - Operational capability in a Year 2000 environment.

    Code of Federal Regulations, 2012 CFR

    2012-04-01

    ... 17 Commodity and Securities Exchanges 3 2012-04-01 2012-04-01 false Operational capability in a Year 2000 environment. 240.15b7-3T Section 240.15b7-3T Commodity and Securities Exchanges SECURITIES... § 240.15b7-3T Operational capability in a Year 2000 environment. (a) This section applies to every...

  1. 17 CFR 240.15b7-3T - Operational capability in a Year 2000 environment.

    Code of Federal Regulations, 2011 CFR

    2011-04-01

    ... 17 Commodity and Securities Exchanges 3 2011-04-01 2011-04-01 false Operational capability in a Year 2000 environment. 240.15b7-3T Section 240.15b7-3T Commodity and Securities Exchanges SECURITIES... § 240.15b7-3T Operational capability in a Year 2000 environment. (a) This section applies to every...

  2. 17 CFR 240.15b7-3T - Operational capability in a Year 2000 environment.

    Code of Federal Regulations, 2013 CFR

    2013-04-01

    ... 17 Commodity and Securities Exchanges 3 2013-04-01 2013-04-01 false Operational capability in a Year 2000 environment. 240.15b7-3T Section 240.15b7-3T Commodity and Securities Exchanges SECURITIES... § 240.15b7-3T Operational capability in a Year 2000 environment. (a) This section applies to every...

  3. 17 CFR 240.15b7-3T - Operational capability in a Year 2000 environment.

    Code of Federal Regulations, 2014 CFR

    2014-04-01

    ... 17 Commodity and Securities Exchanges 4 2014-04-01 2014-04-01 false Operational capability in a Year 2000 environment. 240.15b7-3T Section 240.15b7-3T Commodity and Securities Exchanges SECURITIES... § 240.15b7-3T Operational capability in a Year 2000 environment. (a) This section applies to every...

  4. 17 CFR 240.15b7-3T - Operational capability in a Year 2000 environment.

    Code of Federal Regulations, 2010 CFR

    2010-04-01

    ... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Operational capability in a Year 2000 environment. 240.15b7-3T Section 240.15b7-3T Commodity and Securities Exchanges SECURITIES... § 240.15b7-3T Operational capability in a Year 2000 environment. (a) This section applies to every...

  5. Global Estimates of Errors in Quantum Computation by the Feynman-Vernon Formalism

    NASA Astrophysics Data System (ADS)

    Aurell, Erik

    2018-06-01

    The operation of a quantum computer is considered as a general quantum operation on a mixed state on many qubits followed by a measurement. The general quantum operation is further represented as a Feynman-Vernon double path integral over the histories of the qubits and of an environment, and afterward tracing out the environment. The qubit histories are taken to be paths on the two-sphere S^2 as in Klauder's coherent-state path integral of spin, and the environment is assumed to consist of harmonic oscillators initially in thermal equilibrium, and linearly coupled to to qubit operators \\hat{S}_z. The environment can then be integrated out to give a Feynman-Vernon influence action coupling the forward and backward histories of the qubits. This representation allows to derive in a simple way estimates that the total error of operation of a quantum computer without error correction scales linearly with the number of qubits and the time of operation. It also allows to discuss Kitaev's toric code interacting with an environment in the same manner.

  6. Global Estimates of Errors in Quantum Computation by the Feynman-Vernon Formalism

    NASA Astrophysics Data System (ADS)

    Aurell, Erik

    2018-04-01

    The operation of a quantum computer is considered as a general quantum operation on a mixed state on many qubits followed by a measurement. The general quantum operation is further represented as a Feynman-Vernon double path integral over the histories of the qubits and of an environment, and afterward tracing out the environment. The qubit histories are taken to be paths on the two-sphere S^2 as in Klauder's coherent-state path integral of spin, and the environment is assumed to consist of harmonic oscillators initially in thermal equilibrium, and linearly coupled to to qubit operators \\hat{S}_z . The environment can then be integrated out to give a Feynman-Vernon influence action coupling the forward and backward histories of the qubits. This representation allows to derive in a simple way estimates that the total error of operation of a quantum computer without error correction scales linearly with the number of qubits and the time of operation. It also allows to discuss Kitaev's toric code interacting with an environment in the same manner.

  7. Usability of Operational Performance Support Tools - Findings from Sea Test II

    NASA Technical Reports Server (NTRS)

    Byrne, Vicky; Litaker, Harry; McGuire, Kerry

    2014-01-01

    Sea Test II, aka NASA Extreme Environment Mission Operations 17(NEEMO 17) took place in the Florida Aquarius undersea habitat. This confined underwater environment provides a excellent analog for space habitation providing similarities to space habitation such as hostile environment, difficult logistics, autonomous operations, and remote communications. This study collected subjective feedback on the usability of two performance support tools during the Sea Test II mission, Sept 10-14, 2013; Google Glass and iPAD. The two main objectives: - Assess the overall functionality and usability of each performance support tool in a mission analog environment. - Assess the advantages and disadvantages of each tool when performing operational procedures and Just-In-Time-Training (JITT).

  8. 40 CFR 267.198 - What are the general operating requirements for my tank systems?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... FACILITIES OPERATING UNDER A STANDARDIZED PERMIT Tank Systems § 267.198 What are the general operating... 40 Protection of Environment 28 2012-07-01 2012-07-01 false What are the general operating requirements for my tank systems? 267.198 Section 267.198 Protection of Environment ENVIRONMENTAL PROTECTION...

  9. 40 CFR 267.198 - What are the general operating requirements for my tank systems?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... FACILITIES OPERATING UNDER A STANDARDIZED PERMIT Tank Systems § 267.198 What are the general operating... 40 Protection of Environment 27 2011-07-01 2011-07-01 false What are the general operating requirements for my tank systems? 267.198 Section 267.198 Protection of Environment ENVIRONMENTAL PROTECTION...

  10. 40 CFR 267.198 - What are the general operating requirements for my tank systems?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... FACILITIES OPERATING UNDER A STANDARDIZED PERMIT Tank Systems § 267.198 What are the general operating... 40 Protection of Environment 27 2014-07-01 2014-07-01 false What are the general operating requirements for my tank systems? 267.198 Section 267.198 Protection of Environment ENVIRONMENTAL PROTECTION...

  11. 40 CFR 267.198 - What are the general operating requirements for my tank systems?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... FACILITIES OPERATING UNDER A STANDARDIZED PERMIT Tank Systems § 267.198 What are the general operating... 40 Protection of Environment 28 2013-07-01 2013-07-01 false What are the general operating requirements for my tank systems? 267.198 Section 267.198 Protection of Environment ENVIRONMENTAL PROTECTION...

  12. 40 CFR 267.198 - What are the general operating requirements for my tank systems?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... FACILITIES OPERATING UNDER A STANDARDIZED PERMIT Tank Systems § 267.198 What are the general operating... 40 Protection of Environment 26 2010-07-01 2010-07-01 false What are the general operating requirements for my tank systems? 267.198 Section 267.198 Protection of Environment ENVIRONMENTAL PROTECTION...

  13. Apparatus for providing vibrotactile sensory substitution of force feedback

    NASA Technical Reports Server (NTRS)

    Massimino, Michael J. (Inventor); Sheridan, Thomas B. (Inventor); Patrick, Nicholas J. M. (Inventor)

    1997-01-01

    A feedback apparatus for an operator to control an effector that is remote from the operator to interact with a remote environment has a local input device to be manipulated by the operator. Sensors in the effector's environment are capable of sensing the amplitude of forces arising between the effector and its environment, the direction of application of such forces, or both amplitude and direction. A feedback signal corresponding to such a component of the force, is generated and transmitted to the environment of the operator. The signal is transduced into a vibrotactile sensory substitution signal to which the operator is sensitive. Vibration producing apparatus present the vibrotactile signal to the operator. The full range of the force amplitude may be represented by a single, mechanical vibrator. Vibrotactile display elements can be located on the operator's limbs, such as on the hand, fingers, arms, legs, feet, etc. The location of the application of the force may also be specified by the location of a vibrotactile display on the operator's body. Alternatively, the location may be specified by the frequency of a vibrotactile signal.

  14. An evaluation of grease type ball bearing lubricants operating in various environments

    NASA Technical Reports Server (NTRS)

    Mcmurtrey, E. L.

    1984-01-01

    Because many future spacecraft or space stations will require mechanisms to operate for long periods of time in environments which are adverse to most bearing lubricants, a series of tests has been completed to evaluate 38 grease type lubricants in R-4 size bearings in five different environments for a 1 year period. Four repetitions of each test were made to provide statistical samples. These tests were also used to select four lubricants for 5 year tests in selected environments with five repetitions of each test for statistical samples. In this completed program, 172 test sets have been completed. The three 5 year tests in: (1) continuous operation and (2) start stop operation, with both in vacuum at ambient temperatures, and (3) continuous vacuum operation at 93.3 C have been completed. In both the 1 year and 5 year tests, the best results in all environments have been obtained with a high viscosity index perfluoroalkylpolyether (PFPE) grease.

  15. An evaluation of grease-type ball bearing lubricants operation in various environments

    NASA Technical Reports Server (NTRS)

    Mcmurtrey, E. L.

    1983-01-01

    Because many future spacecraft or space stations will require mechanisms to operate for long periods of time in environments which are adverse to most bearing lubricants, a series of tests is continuing to evaluate 38 grease type lubricants in R-4 size bearings in five different environments for a 1 year period. Four repetitions of each test are made to provide statistical samples. These tests have also been used to select four lubricants for 5 year tests in selected environments with five repetitions of each test for statistical samples. At the present time, 142 test sets have been completed and 30 test sets are underway. The three 5 year tests in (1) continuous operation and (2) start stop operation, with both in vacuum at ambient temperatures, and (3) continuous vacuum operation at 93.3 C are now completed. To date, in both the 1 year and 5 year tests, the best results in all environments have been obtained with a high viscosity index perfluoroalkylpolyether (PFPE) grease.

  16. Advanced Satellite Workstation - An integrated workstation environment for operational support of satellite system planning and analysis

    NASA Astrophysics Data System (ADS)

    Hamilton, Marvin J.; Sutton, Stewart A.

    A prototype integrated environment, the Advanced Satellite Workstation (ASW), which was developed and delivered for evaluation and operator feedback in an operational satellite control center, is described. The current ASW hardware consists of a Sun Workstation and Macintosh II Workstation connected via an ethernet Network Hardware and Software, Laser Disk System, Optical Storage System, and Telemetry Data File Interface. The central objective of ASW is to provide an intelligent decision support and training environment for operator/analysis of complex systems such as satellites. Compared to the many recent workstation implementations that incorporate graphical telemetry displays and expert systems, ASW provides a considerably broader look at intelligent, integrated environments for decision support, based on the premise that the central features of such an environment are intelligent data access and integrated toolsets.

  17. 40 CFR 160.49 - Laboratory operation areas.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 23 2010-07-01 2010-07-01 false Laboratory operation areas. 160.49 Section 160.49 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS GOOD LABORATORY PRACTICE STANDARDS Facilities § 160.49 Laboratory operation areas. Separate laboratory...

  18. 40 CFR 52.272 - Research operations exemptions.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 3 2011-07-01 2011-07-01 false Research operations exemptions. 52.272 Section 52.272 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.272 Research operations...

  19. 40 CFR 52.272 - Research operations exemptions.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 3 2014-07-01 2014-07-01 false Research operations exemptions. 52.272 Section 52.272 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.272 Research operations...

  20. 40 CFR 52.272 - Research operations exemptions.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 3 2012-07-01 2012-07-01 false Research operations exemptions. 52.272 Section 52.272 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS California § 52.272 Research operations...

  1. 40 CFR 190.11 - Variances for unusual operations.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 26 2013-07-01 2013-07-01 false Variances for unusual operations. 190.11 Section 190.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR NUCLEAR POWER OPERATIONS Environmental...

  2. 40 CFR 190.11 - Variances for unusual operations.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 25 2011-07-01 2011-07-01 false Variances for unusual operations. 190.11 Section 190.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR NUCLEAR POWER OPERATIONS Environmental...

  3. 40 CFR 190.10 - Standards for normal operations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Standards for normal operations. 190.10 Section 190.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR NUCLEAR POWER OPERATIONS Environmental...

  4. 40 CFR 190.11 - Variances for unusual operations.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 25 2014-07-01 2014-07-01 false Variances for unusual operations. 190.11 Section 190.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR NUCLEAR POWER OPERATIONS Environmental...

  5. 40 CFR 190.11 - Variances for unusual operations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Variances for unusual operations. 190.11 Section 190.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR NUCLEAR POWER OPERATIONS Environmental...

  6. 40 CFR 190.10 - Standards for normal operations.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 26 2012-07-01 2011-07-01 true Standards for normal operations. 190.10 Section 190.10 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR NUCLEAR POWER OPERATIONS Environmental Standards...

  7. 40 CFR 190.11 - Variances for unusual operations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Variances for unusual operations. 190.11 Section 190.11 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) RADIATION PROTECTION PROGRAMS ENVIRONMENTAL RADIATION PROTECTION STANDARDS FOR NUCLEAR POWER OPERATIONS Environmental...

  8. 40 CFR 160.49 - Laboratory operation areas.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 24 2011-07-01 2011-07-01 false Laboratory operation areas. 160.49 Section 160.49 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) PESTICIDE PROGRAMS GOOD LABORATORY PRACTICE STANDARDS Facilities § 160.49 Laboratory operation areas. Separate laboratory...

  9. AERIS - applications for the environment : real-time information synthesis : eco-lanes operational scenario modeling report.

    DOT National Transportation Integrated Search

    2014-12-01

    This report constitutes the detailed modeling and evaluation results of the Eco-Lanes Operational Scenario defined by the Applications for the Environment: Real-Time Information Synthesis (AERIS) Program. The Operational Scenario constitutes six appl...

  10. Exploration of Force Transition in Stability Operations Using Multi-Agent Simulation

    DTIC Science & Technology

    2006-09-01

    risk, mission failure risk, and time in the context of the operational threat environment. The Pythagoras Multi-Agent Simulation and Data Farming...NUMBER OF PAGES 173 14. SUBJECT TERMS Stability Operations, Peace Operations, Data Farming, Pythagoras , Agent- Based Model, Multi-Agent Simulation...the operational threat environment. The Pythagoras Multi-Agent Simulation and Data Farming techniques are used to investigate force-level

  11. An Expert System for Developing a Full Scale Development Statement of Work

    DTIC Science & Technology

    1989-09-01

    Transportability: 3.5.1.3* Specialty Engineering System Safety: Aerospace Meteorlogical Environment: Preservation, Packaging, and Packing... METEORLOGICAL ENVIRONMENT:’,tn). area is ’AEROSPACE METEORLOGICAL ENVIRONMENT’ ASK ( ’The system will require operation, non-operation, transport, and/or

  12. 40 CFR 265.31 - Maintenance and operation of facility.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ..., soil, or surface water which could threaten human health or the -environment. ... 40 Protection of Environment 25 2010-07-01 2010-07-01 false Maintenance and operation of facility. 265.31 Section 265.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID...

  13. 43 CFR 3162.5 - Environment and safety.

    Code of Federal Regulations, 2014 CFR

    2014-10-01

    ... 43 Public Lands: Interior 2 2014-10-01 2014-10-01 false Environment and safety. 3162.5 Section 3162.5 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND... for Operating Rights Owners and Operators § 3162.5 Environment and safety. ...

  14. 43 CFR 3162.5 - Environment and safety.

    Code of Federal Regulations, 2012 CFR

    2012-10-01

    ... 43 Public Lands: Interior 2 2012-10-01 2012-10-01 false Environment and safety. 3162.5 Section 3162.5 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND... for Operating Rights Owners and Operators § 3162.5 Environment and safety. ...

  15. 43 CFR 3162.5 - Environment and safety.

    Code of Federal Regulations, 2013 CFR

    2013-10-01

    ... 43 Public Lands: Interior 2 2013-10-01 2013-10-01 false Environment and safety. 3162.5 Section 3162.5 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND... for Operating Rights Owners and Operators § 3162.5 Environment and safety. ...

  16. 43 CFR 3162.5 - Environment and safety.

    Code of Federal Regulations, 2011 CFR

    2011-10-01

    ... 43 Public Lands: Interior 2 2011-10-01 2011-10-01 false Environment and safety. 3162.5 Section 3162.5 Public Lands: Interior Regulations Relating to Public Lands (Continued) BUREAU OF LAND... for Operating Rights Owners and Operators § 3162.5 Environment and safety. ...

  17. 40 CFR 792.49 - Laboratory operation areas.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 31 2010-07-01 2010-07-01 true Laboratory operation areas. 792.49 Section 792.49 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT (CONTINUED) GOOD LABORATORY PRACTICE STANDARDS Facilities § 792.49 Laboratory operation areas...

  18. 40 CFR 281.32 - General operating requirements.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... constantly; (b) Where equipped with cathodic protection, be operated and maintained by a person with... 40 Protection of Environment 26 2010-07-01 2010-07-01 false General operating requirements. 281.32 Section 281.32 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES...

  19. 40 CFR 281.32 - General operating requirements.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... constantly; (b) Where equipped with cathodic protection, be operated and maintained by a person with... 40 Protection of Environment 27 2011-07-01 2011-07-01 false General operating requirements. 281.32 Section 281.32 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES...

  20. A Virtual Mission Operations Center: Collaborative Environment

    NASA Technical Reports Server (NTRS)

    Medina, Barbara; Bussman, Marie; Obenschain, Arthur F. (Technical Monitor)

    2002-01-01

    The Virtual Mission Operations Center - Collaborative Environment (VMOC-CE) intent is to have a central access point for all the resources used in a collaborative mission operations environment to assist mission operators in communicating on-site and off-site in the investigation and resolution of anomalies. It is a framework that as a minimum incorporates online chat, realtime file sharing and remote application sharing components in one central location. The use of a collaborative environment in mission operations opens up the possibilities for a central framework for other project members to access and interact with mission operations staff remotely. The goal of the Virtual Mission Operations Center (VMOC) Project is to identify, develop, and infuse technology to enable mission control by on-call personnel in geographically dispersed locations. In order to achieve this goal, the following capabilities are needed: Autonomous mission control systems Automated systems to contact on-call personnel Synthesis and presentation of mission control status and history information Desktop tools for data and situation analysis Secure mechanism for remote collaboration commanding Collaborative environment for remote cooperative work The VMOC-CE is a collaborative environment that facilitates remote cooperative work. It is an application instance of the Virtual System Design Environment (VSDE), developed by NASA Goddard Space Flight Center's (GSFC) Systems Engineering Services & Advanced Concepts (SESAC) Branch. The VSDE is a web-based portal that includes a knowledge repository and collaborative environment to serve science and engineering teams in product development. It is a "one stop shop" for product design, providing users real-time access to product development data, engineering and management tools, and relevant design specifications and resources through the Internet. The initial focus of the VSDE has been to serve teams working in the early portion of the system/product lifecycle - concept development, proposal preparation, and formulation. The VMOC-CE expands the application of the VSDE into the operations portion of the system lifecycle. It will enable meaningful and real-time collaboration regardless of the geographical distribution of project team members. Team members will be able to interact in satellite operations, specifically for resolving anomalies, through access to a desktop computer and the Internet. Mission Operations Management will be able to participate and monitor up to the minute status of anomalies or other mission operations issues. In this paper we present the VMOC-CE project, system capabilities, and technologies.

  1. 40 CFR 60.3043 - What operating parameter monitoring equipment must I install, and what operating parameters must...

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 6 2011-07-01 2011-07-01 false What operating parameter monitoring equipment must I install, and what operating parameters must I monitor? 60.3043 Section 60.3043 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) STANDARDS OF PERFORMANCE FOR NEW STATIONARY SOURCES Emission...

  2. Human Performance Issues of Lunar-Sited Teleoperations

    NASA Technical Reports Server (NTRS)

    Kaiser, Mary K.; Null, Cynthia H. (Technical Monitor)

    1995-01-01

    Teleoperations in terrestrial environments present a number of challenges to system operators and designers. Transmission lags, restricted visual fields, and reduced or distorted tactile/kinesthetic feedback can compromise performance, especially for innerloop control tasks (e.g., vehicle or manipulator control). These problems are likely to be exacerbated in lunar operations, since teleoperation may occur across large distances. Further, the lunar environment will introduce unique concerns. For example, the teleoperated systems will reflect the reduced gravity of the moon. In addition to the novelty of these dynamics, operators will often have to cope with them while physically located in a terrestrial or microgravity environment. Similarly, the optical characteristics of the lunar environment differ from our usual experience (e.g., lack of atmospheric attenuation) in ways that may impact normative depth, distance, and motion perception. These human factors issues are related to the question of humans adapting to a lunar environment. However, teleoperations requires the operator to maintain functionality in both the control station and end-effector environments, defeating more straightforward environmental adaptation strategies.

  3. Analyzing the Impacts of Natural Environments on Launch and Landing Availability for NASA's Eploration Systems Development Programs

    NASA Technical Reports Server (NTRS)

    Altino, Karen M.; Burns, K. Lee; Barbre, Robert E.; Leahy, Frank B.

    2014-01-01

    NASA is developing new capabilities for human and scientific exploration beyond Earth orbit. Natural environments information is an important asset for NASA's development of the next generation space transportation system as part of the Exploration Systems Development Program, which includes the Space Launch System (SLS) and MultiPurpose Crew Vehicle (MPCV) Programs. Natural terrestrial environment conditions - such as wind, lightning and sea states - can affect vehicle safety and performance during multiple mission phases ranging from prelaunch ground processing to landing and recovery operations, including all potential abort scenarios. Space vehicles are particularly sensitive to these environments during the launch/ascent and the entry/landing phases of mission operations. The Marshall Space Flight Center (MSFC) Natural Environments Branch provides engineering design support for NASA space vehicle projects and programs by providing design engineers and mission planners with natural environments definitions as well as performing custom analyses to help characterize the impacts the natural environment may have on vehicle performance. One such analysis involves assessing the impact of natural environments to operational availability. Climatological time series of operational surface weather observations are used to calculate probabilities of meeting or exceeding various sets of hypothetical vehicle-specific parametric constraint thresholds.

  4. Operation of commercial R3000 processors in the low earth orbit (LEO) space environment

    NASA Astrophysics Data System (ADS)

    Kaschmitter, J. L.; Shaeffer, D. L.; Colella, N. J.; McKnett, C. L.; Coakley, P. G.

    1991-12-01

    Spacecraft processors must operate with minimal degradation of performance in the LEO radiation environment, which includes the effects of total accumulated ionizing dose and single event phenomena (SEP) caused by protons and cosmic rays. Commercially available microprocessors can offer a number of advantages relative to radiation-hardened devices but are not normally designed to tolerate effects induced by the LEO environment. Extensive testing of the MIPS R3000 Reduced Instruction Set Computer (RISC) microprocessor family for operation in LEO environments is reported. The authors have characterized total dose and SEP effects for altitudes and inclinations of interest to systems operating in LEO, and they postulate techniques for detection and alleviation of SEP effects based on experimental results.

  5. An Operating Environment for the Jellybean Machine

    DTIC Science & Technology

    1988-05-01

    MODEL 48 5.4.4 Restarting a Context The operating system provides one primitive message (RESTART-CONTEXT) and two system calls (XFERID and XFER.ADDR) to...efficient, powerful services is reqired to support this "stem. To provide this supportive operating environment, I developed an operating system kernel that...serves many of the initial needs of our machine. This Jellybean Operating System Software provides an object- based storage model, where typed

  6. Immersive Environment Technologies for Mars Exploration

    NASA Technical Reports Server (NTRS)

    Wright, John R.; Hartman, Frank

    2000-01-01

    JPL's charter includes the unmanned exploration of the Solar System. One of the tools for exploring other planets is the rover as exemplified by Sojourner on the Mars Pathfinder mission. The light speed turnaround time between Earth and the outer planets precludes the use of teleoperated rovers so autonomous operations are built in to the current and upcoming generation devices. As the level of autonomy increases, the mode of operations shifts from low-level specification of activities to a higher-level specification of goals. To support this higher-level activity, it is necessary to provide the operator with an effective understanding of the in-situ environment and also the tools needed to specify the higher-level goals. Immersive environments provide the needed sense of presence to achieve this goal. Use of immersive environments at JPL has two main thrusts that will be discussed in this talk. One is the generation of 3D models of the in-situ environment, in particular the merging of models from different sensors, different modes (orbital, descent, and lander), and even different missions. The other is the use of various tools to visualize the environment within which the rover will be operating to maximize the understanding by the operator. A suite of tools is under development which provide an integrated view into the environment while providing a variety of modes of visualization. This allows the operator to smoothly switch from one mode to another depending on the information and presentation desired.

  7. 40 CFR 63.126 - Transfer operations provisions-reference control technology.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 9 2011-07-01 2011-07-01 false Transfer operations provisions-reference control technology. 63.126 Section 63.126 Protection of Environment ENVIRONMENTAL PROTECTION... Wastewater § 63.126 Transfer operations provisions—reference control technology. (a) For each Group 1...

  8. 40 CFR 63.126 - Transfer operations provisions-reference control technology.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 10 2012-07-01 2012-07-01 false Transfer operations provisions-reference control technology. 63.126 Section 63.126 Protection of Environment ENVIRONMENTAL PROTECTION... Wastewater § 63.126 Transfer operations provisions—reference control technology. (a) For each Group 1...

  9. 40 CFR 63.126 - Transfer operations provisions-reference control technology.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 10 2013-07-01 2013-07-01 false Transfer operations provisions-reference control technology. 63.126 Section 63.126 Protection of Environment ENVIRONMENTAL PROTECTION... Wastewater § 63.126 Transfer operations provisions—reference control technology. (a) For each Group 1...

  10. 40 CFR 63.126 - Transfer operations provisions-reference control technology.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 9 2010-07-01 2010-07-01 false Transfer operations provisions-reference control technology. 63.126 Section 63.126 Protection of Environment ENVIRONMENTAL PROTECTION... Wastewater § 63.126 Transfer operations provisions—reference control technology. (a) For each Group 1...

  11. Cost-benefit analysis and emission reduction of energy efficient lighting at the Universiti Tenaga Nasional.

    PubMed

    Ganandran, G S B; Mahlia, T M I; Ong, Hwai Chyuan; Rismanchi, B; Chong, W T

    2014-01-01

    This paper reports the result of an investigation on the potential energy saving of the lighting systems at selected buildings of the Universiti Tenaga Nasional. The scope of this project includes evaluation of the lighting system in the Library, Admin Building, College of Engineering, College of Information Technology, Apartments, and COE Food court of the university. The main objectives of this project are to design the proper retrofit scenario and to calculate the potential electricity saving, the payback period, and the potential environmental benefits. In this survey the policy for retrofitting the old lighting system with the new energy saving LEDs starts with 10% for the first year and continues constantly for 10 years until all the lighting systems have been replaced. The result of the life cycle analysis reveals that after four years, the selected buildings will bring profit for the investment.

  12. The 2003 and 2007 wildfires in southern California: Chapter 5 in Natural Disasters and Adaptation to Climate Change

    USGS Publications Warehouse

    Keeley, Jon E.; Syphard, Alexandra D.; Fotheringham, C.J.; Boulter, Sarah; Palutikof, Jean; Karoly, David John; Guitart, Daniela

    2013-01-01

    Although many residents of southern California have long recognised that wildfires in the region are an ongoing, constant risk to lives and property, the enormity of the regional fire hazard caught the world’s attention during the southern California firestorms of 2003 (Figure 5.1). Beginning on 21 October, a series of fourteen wildfires broke out across the five-county region under severe Santa Ana winds, and within two weeks, more than 300,000 ha had burned (Keeley et al., 2004). The event was one of the costliest in the state’s history, with more than 3,600 homes damaged or destroyed and twenty-four fatalities. Suppression costs for the 12,000 firefighters have been estimated at US$120 million, and the total response and damage cost has been estimated at more than US$3 billion (COES, 2004). [Excerpt

  13. Fuel prices, emission standards, and generation costs for coal vs natural gas power plants.

    PubMed

    Pratson, Lincoln F; Haerer, Drew; Patiño-Echeverri, Dalia

    2013-05-07

    Low natural gas prices and stricter, federal emission regulations are promoting a shift away from coal power plants and toward natural gas plants as the lowest-cost means of generating electricity in the United States. By estimating the cost of electricity generation (COE) for 304 coal and 358 natural gas plants, we show that the economic viability of 9% of current coal capacity is challenged by low natural gas prices, while another 56% would be challenged by the stricter emission regulations. Under the current regulations, coal plants would again become the dominant least-cost generation option should the ratio of average natural gas to coal prices (NG2CP) rise to 1.8 (it was 1.42 in February 2012). If the more stringent emission standards are enforced, however, natural gas plants would remain cost competitive with a majority of coal plants for NG2CPs up to 4.3.

  14. Optimal damping profile ratios for stabilization of perfectly matched layers in general anisotropic media

    DOE PAGES

    Gao, Kai; Huang, Lianjie

    2017-11-13

    Conventional perfectly matched layers (PML) can be unstable for certain kinds of anisotropic media. Multi-axial PML removes such instability using nonzero damping coe cients in the directions tangential with the PML interface. While using non-zero damping pro le ratios can stabilize PML, it is important to obtain the smallest possible damping pro le ratios to minimize arti cial re ections caused by these non-zero ratios, particularly for 3D general anisotropic media. Using the eigenvectors of the PML system matrix, we develop a straightforward and e cient numerical algorithm to determine the optimal damping pro le ratios to stabilize PML inmore » 2D and 3D general anisotropic media. Numerical examples show that our algorithm provides optimal damping pro le ratios to ensure the stability of PML and complex-frequency-shifted PML for elastic-wave modeling in 2D and 3D general anisotropic media.« less

  15. Cost-Benefit Analysis and Emission Reduction of Energy Efficient Lighting at the Universiti Tenaga Nasional

    PubMed Central

    Ganandran, G. S. B.; Mahlia, T. M. I.; Ong, Hwai Chyuan; Rismanchi, B.; Chong, W. T.

    2014-01-01

    This paper reports the result of an investigation on the potential energy saving of the lighting systems at selected buildings of the Universiti Tenaga Nasional. The scope of this project includes evaluation of the lighting system in the Library, Admin Building, College of Engineering, College of Information Technology, Apartments, and COE Food court of the university. The main objectives of this project are to design the proper retrofit scenario and to calculate the potential electricity saving, the payback period, and the potential environmental benefits. In this survey the policy for retrofitting the old lighting system with the new energy saving LEDs starts with 10% for the first year and continues constantly for 10 years until all the lighting systems have been replaced. The result of the life cycle analysis reveals that after four years, the selected buildings will bring profit for the investment. PMID:25133258

  16. Optimal damping profile ratios for stabilization of perfectly matched layers in general anisotropic media

    DOE Office of Scientific and Technical Information (OSTI.GOV)

    Gao, Kai; Huang, Lianjie

    Conventional perfectly matched layers (PML) can be unstable for certain kinds of anisotropic media. Multi-axial PML removes such instability using nonzero damping coe cients in the directions tangential with the PML interface. While using non-zero damping pro le ratios can stabilize PML, it is important to obtain the smallest possible damping pro le ratios to minimize arti cial re ections caused by these non-zero ratios, particularly for 3D general anisotropic media. Using the eigenvectors of the PML system matrix, we develop a straightforward and e cient numerical algorithm to determine the optimal damping pro le ratios to stabilize PML inmore » 2D and 3D general anisotropic media. Numerical examples show that our algorithm provides optimal damping pro le ratios to ensure the stability of PML and complex-frequency-shifted PML for elastic-wave modeling in 2D and 3D general anisotropic media.« less

  17. A short introduction to the status and motivation for reversed field pinch and compact toroid research

    NASA Astrophysics Data System (ADS)

    Dreicer, H.

    1987-09-01

    Potential commercial fusion power systems must be acceptable from a safety and environmental standpoint. They must also promise to be competitive with other sources of energy (i.e., fossil, fission, etc.) when considered from the standpoint of the cost of electricity (COE) and the unit direct cost (UDC) in dollars/kWe. These costs are affected by a host of factors including recirculating power, plant availability, construction time, capital cost, etc., and are influenced by technological complexity. In an attempt to meet these requirements, the emphasis of fusion research in the United States has been moving toward smaller, lower-cost systems. There is increased interest in higher beta tokamaks and stellarators, and in compact alternate concepts such as the Reversed Field Pinch (RFP) and the Compact Toroids (CTs) which are, in part, the subject of this paper.

  18. The genesis of neurosurgery and the evolution of the neurosurgical operative environment: part I-prehistory to 2003.

    PubMed

    Liu, Charles Y; Apuzzo, Michael L J

    2003-01-01

    Despite its singular importance, little attention has been given to the neurosurgical operative environment in the scientific and medical literature. This article focuses attention on the development of neurosurgery and the parallel emergence of its operative setting. The operative environment has, to a large extent, defined the "state of the art and science" of neurosurgery, which is now undergoing rapid reinvention. During the course of its initial invention, major milestones in the development of neurosurgery have included the definition of anatomy, consolidation of a scientific basis, and incorporation of the practicalities of anesthesia and antisepsis and later operative technical adjuvants for further refinement of action and minimalism. The progress, previously long and laborious in emergence, is currently undergoing rapid evolution. Throughout its evolution, the discipline has assimilated the most effective tools of modernity into the operative environment, leading eventually to the entity known as the operating room. In the decades leading to the present, progressive minimalization of manipulation and the emergence of more refined operative definition with increasing precision are evident, with concurrent miniaturization of attendant computerized support systems, sensors, robotic interfaces, and imaging devices. These developments over time have led to the invention of neurosurgery and the establishment of the current state-of-the-art neurosurgical operating room as we understand it, and indeed, to a broader definition of the entity itself. To remain current, each neurosurgeon should periodically reconsider his or her personal operative environment and its functional design with reference to modernity of practice as currently defined.

  19. The Joint Master Operational Planner

    DTIC Science & Technology

    2016-04-04

    Operational Planner Program, that will produce planners that are able to understand the strategic- operational environment, properly advise commanders, and...Planner Program, that will produce planners that are able to understand the strategic-operational environment, properly advise commanders, and devise...states struggle to exercise even nominal power within their borders, and the people see the government as an entity that seeks only to keep itself in

  20. 40 CFR 267.201 - What must I do when I stop operating the tank system?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... OPERATING UNDER A STANDARDIZED PERMIT Tank Systems § 267.201 What must I do when I stop operating the tank... 40 Protection of Environment 28 2012-07-01 2012-07-01 false What must I do when I stop operating the tank system? 267.201 Section 267.201 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...

  1. 40 CFR 267.201 - What must I do when I stop operating the tank system?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... OPERATING UNDER A STANDARDIZED PERMIT Tank Systems § 267.201 What must I do when I stop operating the tank... 40 Protection of Environment 28 2013-07-01 2013-07-01 false What must I do when I stop operating the tank system? 267.201 Section 267.201 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...

  2. 40 CFR 267.201 - What must I do when I stop operating the tank system?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... OPERATING UNDER A STANDARDIZED PERMIT Tank Systems § 267.201 What must I do when I stop operating the tank... 40 Protection of Environment 26 2010-07-01 2010-07-01 false What must I do when I stop operating the tank system? 267.201 Section 267.201 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...

  3. 40 CFR 267.201 - What must I do when I stop operating the tank system?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... OPERATING UNDER A STANDARDIZED PERMIT Tank Systems § 267.201 What must I do when I stop operating the tank... 40 Protection of Environment 27 2011-07-01 2011-07-01 false What must I do when I stop operating the tank system? 267.201 Section 267.201 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...

  4. 40 CFR 267.201 - What must I do when I stop operating the tank system?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... OPERATING UNDER A STANDARDIZED PERMIT Tank Systems § 267.201 What must I do when I stop operating the tank... 40 Protection of Environment 27 2014-07-01 2014-07-01 false What must I do when I stop operating the tank system? 267.201 Section 267.201 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY...

  5. Challenges and Opportunities of Operation Enduring Freedom/Operation Iraqi Freedom Veterans with Disabilities Transitioning into Learning and Workplace Environments

    ERIC Educational Resources Information Center

    Ostovary, Fariba; Dapprich, Janet

    2011-01-01

    This article presents issues related to disabled military servicemen and women who are transitioning to civilian life. The emphasis is on the experience of veterans serving in the Operation Enduring Freedom (OEF) and Operation Iraqi Freedom (OIF) as they reintegrate into civilian workplace and learning environments. The authors begin with an…

  6. 40 CFR 60.373 - Monitoring of emissions and operations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 6 2010-07-01 2010-07-01 false Monitoring of emissions and operations. 60.373 Section 60.373 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR...-Acid Battery Manufacturing Plants § 60.373 Monitoring of emissions and operations. The owner or...

  7. 40 CFR 52.1834 - Minor source permit to operate program.

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 4 2014-07-01 2014-07-01 false Minor source permit to operate program. 52.1834 Section 52.1834 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Minor source permit to operate program. Emission limitations and related provisions, which, in...

  8. 40 CFR 52.1834 - Minor source permit to operate program.

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 4 2012-07-01 2012-07-01 false Minor source permit to operate program. 52.1834 Section 52.1834 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Minor source permit to operate program. Emission limitations and related provisions, which, in...

  9. 40 CFR 52.1834 - Minor source permit to operate program.

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 4 2013-07-01 2013-07-01 false Minor source permit to operate program. 52.1834 Section 52.1834 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR... Minor source permit to operate program. Emission limitations and related provisions, which, in...

  10. 40 CFR 190.10 - Standards for normal operations.

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... Standards for the Uranium Fuel Cycle § 190.10 Standards for normal operations. Operations covered by this... radioactive materials, radon and its daughters excepted, to the general environment from uranium fuel cycle... the general environment from the entire uranium fuel cycle, per gigawatt-year of electrical energy...

  11. 30 CFR 250.199 - Paperwork Reduction Act statements-information collection.

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... be safe and protect the human, marine, and coastal environment, and will result in diligent..., marine, and coastal environment. (5) Subpart E, Oil and Gas Well-Completion Operations (1010-0067) To... that well-completion operations are safe and protect the human, marine, and coastal environment. (6...

  12. Ada Run Time Support Environments and a common APSE Interface Set. [Ada Programming Support Environment

    NASA Technical Reports Server (NTRS)

    Mckay, C. W.; Bown, R. L.

    1985-01-01

    The paper discusses the importance of linking Ada Run Time Support Environments to the Common Ada Programming Support Environment (APSE) Interface Set (CAIS). A non-stop network operating systems scenario is presented to serve as a forum for identifying the important issues. The network operating system exemplifies the issues involved in the NASA Space Station data management system.

  13. Continued Optical Sensor Operations in a Laser Environment

    DTIC Science & Technology

    2012-10-01

    Power (W) Aperture (mm) Intensity at target (W/m2) Gain of laser to desired signal handheld 532 0.5 1.5 1120 @ 25 km 5.6 × 1024 Industrial diode ...AIR UNIVERSITY AIR WAR COLLEGE Continued Optical Sensor Operations in a Laser Environment WILLIAM J. DIEHL Commander, USN...COVERED 00-00-2012 to 00-00-2012 4. TITLE AND SUBTITLE Continued Optical Sensor Operations in a Laser Environment 5a. CONTRACT NUMBER 5b. GRANT

  14. STOL Traffic environment and operational procedures

    NASA Technical Reports Server (NTRS)

    Schlundt, R. W.; Dewolf, R. W.; Ausrotas, R. A.; Curry, R. E.; Demaio, D.; Keene, D. W.; Speyer, J. L.; Weinreich, M.; Zeldin, S.

    1972-01-01

    The expected traffic environment for an intercity STOL transportation system is examined, and operational procedures are discussed in order to identify problem areas which impact STOL avionics requirements. Factors considered include: traffic densities, STOL/CTOL/VTOL traffic mix, the expect ATC environment, aircraft noise models and community noise models and community noise impact, flight paths for noise abatement, wind considerations affecting landing, approach and landing considerations, STOLport site selection, runway capacity, and STOL operations at jetports, suburban airports, and separate STOLports.

  15. Space station operations management

    NASA Technical Reports Server (NTRS)

    Cannon, Kathleen V.

    1989-01-01

    Space Station Freedom operations management concepts must be responsive to the unique challenges presented by the permanently manned international laboratory. Space Station Freedom will be assembled over a three year period where the operational environment will change as significant capability plateaus are reached. First Element Launch, Man-Tended Capability, and Permanent Manned Capability, represent milestones in operational capability that is increasing toward mature operations capability. Operations management concepts are being developed to accomodate the varying operational capabilities during assembly, as well as the mature operational environment. This paper describes operations management concepts designed to accomodate the uniqueness of Space Station Freedoom, utilizing tools and processes that seek to control operations costs.

  16. 40 CFR 63.7945 - What are my monitoring installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2011 CFR

    2011-07-01

    ... 40 Protection of Environment 13 2011-07-01 2011-07-01 false What are my monitoring installation, operation, and maintenance requirements? 63.7945 Section 63.7945 Protection of Environment ENVIRONMENTAL... Remediation Continuous Monitoring Systems § 63.7945 What are my monitoring installation, operation, and...

  17. 40 CFR 63.7945 - What are my monitoring installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2012 CFR

    2012-07-01

    ... 40 Protection of Environment 14 2012-07-01 2011-07-01 true What are my monitoring installation, operation, and maintenance requirements? 63.7945 Section 63.7945 Protection of Environment ENVIRONMENTAL... Remediation Continuous Monitoring Systems § 63.7945 What are my monitoring installation, operation, and...

  18. 40 CFR 63.7945 - What are my monitoring installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2014 CFR

    2014-07-01

    ... 40 Protection of Environment 14 2014-07-01 2014-07-01 false What are my monitoring installation, operation, and maintenance requirements? 63.7945 Section 63.7945 Protection of Environment ENVIRONMENTAL... Remediation Continuous Monitoring Systems § 63.7945 What are my monitoring installation, operation, and...

  19. 40 CFR 63.7945 - What are my monitoring installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2010 CFR

    2010-07-01

    ... 40 Protection of Environment 13 2010-07-01 2010-07-01 false What are my monitoring installation, operation, and maintenance requirements? 63.7945 Section 63.7945 Protection of Environment ENVIRONMENTAL... Remediation Continuous Monitoring Systems § 63.7945 What are my monitoring installation, operation, and...

  20. 40 CFR 63.7945 - What are my monitoring installation, operation, and maintenance requirements?

    Code of Federal Regulations, 2013 CFR

    2013-07-01

    ... 40 Protection of Environment 14 2013-07-01 2013-07-01 false What are my monitoring installation, operation, and maintenance requirements? 63.7945 Section 63.7945 Protection of Environment ENVIRONMENTAL... Remediation Continuous Monitoring Systems § 63.7945 What are my monitoring installation, operation, and...

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